{"text_format":"3","workbook":"xlsx","n_sheets":1,"sheets":["Sheet1"],"bounds":{"halvings":1},"cells_cut":76,"read":"whole","date_system":"1900"}

{"sheet":"Sheet1","index":0,"n_rows":3649,"n_cols":26,"rows_kept":2250,"cut":true,"bounds":{"rows_first":1000,"rows_last":250,"rows_between":1000,"halvings":1}}
["Protein accession","Protein description","Gene name","MW [kDa]","Score","Coverage [%]","Peptides","PSMs","Unique peptides","con_1","con_2","con_3","pso_1","pso_2","pso_3","pso/con Ratio","pso/con P value","Subcellular localization\r","Biological Process","Cellular Component","Molecular Function","KEGG KO No.","KEGG Gene","KEGG pathway","IPR ID","Domain description\r"]
["A0A075B6H9","Immunoglobulin lambda variable 4-69 OS=Homo sapiens OX=9606 GN=IGLV4-69","IGLV4-69",12.773,3.6372,14.3,2,2,2,1.07,1.015,1.015,0.972,0.839,1.101,0.939,0.443,"extracellular\r","GO:0002376 immune system process; GO:0002377 immunoglobulin production; GO:0002440 production of molecular mediator of immune response; GO:0006955 immune response; GO:0050896 response to stimulus; GO:0002250 adaptive immune response; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0071944 cell periphery; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; ","GO:0005515 protein binding; GO:0003823 antigen binding; GO:0005488 binding; ",{"$nulls":3},"IPR007110; IPR013783; IPR013106; IPR003599; ","Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin V-set domain; Immunoglobulin subtype; \r"]
["A0A075B6I0","Immunoglobulin lambda variable 8-61 OS=Homo sapiens OX=9606 GN=IGLV8-61","IGLV8-61",12.814,2.9092,14.8,2,4,2,1.071,0.948,0.995,0.984,1,1.016,0.995,0.929,"extracellular\r","GO:0002376 immune system process; GO:0002377 immunoglobulin production; GO:0002440 production of molecular mediator of immune response; GO:0006955 immune response; GO:0050896 response to stimulus; GO:0002250 adaptive immune response; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0071944 cell periphery; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; ","GO:0005515 protein binding; GO:0003823 antigen binding; GO:0005488 binding; ",{"$nulls":3},"IPR007110; IPR013783; IPR003599; IPR013106; ","Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin subtype; Immunoglobulin V-set domain; \r"]
["A0A075B6I9","Immunoglobulin lambda variable 7-46 OS=Homo sapiens OX=9606 GN=IGLV7-46","IGLV7-46",12.468,3.0942,13.7,2,4,2,null,0.777,0.685,1.707,1.206,0.609,1.606,0.394,"extracellular\r","GO:0002376 immune system process; GO:0002377 immunoglobulin production; GO:0002440 production of molecular mediator of immune response; GO:0006955 immune response; GO:0050896 response to stimulus; GO:0002250 adaptive immune response; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0071944 cell periphery; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; ","GO:0005515 protein binding; GO:0003823 antigen binding; GO:0005488 binding; ",{"$nulls":3},"IPR007110; IPR013783; IPR003599; IPR013106; ","Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin subtype; Immunoglobulin V-set domain; \r"]
["A0A075B6K0","Immunoglobulin lambda variable 3-16 OS=Homo sapiens OX=9606 GN=IGLV3-16","IGLV3-16",12.466,2.6879,18.3,2,3,1,0.816,0.84,0.793,1.146,1.136,1.254,1.444,0.000503,"extracellular\r","GO:0002376 immune system process; GO:0002377 immunoglobulin production; GO:0002440 production of molecular mediator of immune response; GO:0006955 immune response; GO:0050896 response to stimulus; GO:0002250 adaptive immune response; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0071944 cell periphery; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; ","GO:0005515 protein binding; GO:0003823 antigen binding; GO:0005488 binding; ",{"$nulls":3},"IPR007110; IPR013783; IPR003599; IPR013106; ","Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin subtype; Immunoglobulin V-set domain; \r"]
["A0A075B6K4","Immunoglobulin lambda variable 3-10 OS=Homo sapiens OX=9606 GN=IGLV3-10","IGLV3-10",12.441,5.0803,15.7,2,3,1,0.833,0.91,0.84,0.961,1.165,1.273,1.316,0.0375,"extracellular\r","GO:0002376 immune system process; GO:0002377 immunoglobulin production; GO:0002440 production of molecular mediator of immune response; GO:0006955 immune response; GO:0050896 response to stimulus; GO:0002250 adaptive immune response; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0071944 cell periphery; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; ","GO:0005515 protein binding; GO:0003823 antigen binding; GO:0005488 binding; ",{"$nulls":3},"IPR007110; IPR013783; IPR003599; IPR013106; ","Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin subtype; Immunoglobulin V-set domain; \r"]
["A0A075B6K5","Immunoglobulin lambda variable 3-9 OS=Homo sapiens OX=9606 GN=IGLV3-9","IGLV3-9",12.332,38.793,23.5,2,3,2,0.885,0.989,0.912,1.034,1.086,1.045,1.136,0.0242,"extracellular\r","GO:0002376 immune system process; GO:0006955 immune response; GO:0050896 response to stimulus; GO:0002377 immunoglobulin production; GO:0002440 production of molecular mediator of immune response; ","GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005576 extracellular region; ","GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR007110; IPR013783; IPR013106; IPR003599; ","Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin V-set domain; Immunoglobulin subtype; \r"]
["A0A0A0MS15","Immunoglobulin heavy variable 3-49 OS=Homo sapiens OX=9606 GN=IGHV3-49","IGHV3-49",13.056,2.8532,7.6,1,1,1,0.957,0.968,0.947,1.05,0.983,1.099,1.091,0.0603,"extracellular\r","GO:0044700 single organism signaling; GO:0002694 regulation of leukocyte activation; GO:0016064 immunoglobulin mediated immune response; GO:0007166 cell surface receptor signaling pathway; GO:0098542 defense response to other organism; GO:0044699 single-organism process; GO:0051249 regulation of lymphocyte activation; GO:0009607 response to biotic stimulus; GO:0051234 establishment of localization; GO:0006909 phagocytosis; GO:0006956 complement activation; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0002250 adaptive immune response; GO:0006958 complement activation, classical pathway; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0050851 antigen receptor-mediated signaling pathway; GO:0044765 single-organism transport; GO:0051716 cellular response to stimulus; GO:0006911 phagocytosis, engulfment; GO:0002443 leukocyte mediated immunity; GO:0006910 phagocytosis, recognition; GO:0050864 regulation of B cell activation; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0051251 positive regulation of lymphocyte activation; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0050853 B cell receptor signaling pathway; GO:0006810 transport; GO:0050865 regulation of cell activation; GO:0050789 regulation of biological process; GO:0048583 regulation of response to stimulus; GO:0002682 regulation of immune system process; GO:0006952 defense response; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0002252 immune effector process; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0010324 membrane invagination; GO:0006959 humoral immune response; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0008037 cell recognition; GO:0051707 response to other organism; GO:0045087 innate immune response; GO:0071704 organic substance metabolic process; GO:0019724 B cell mediated immunity; GO:0099024 plasma membrane invagination; GO:0050867 positive regulation of cell activation; GO:1902578 single-organism localization; GO:0050871 positive regulation of B cell activation; GO:0002757 immune response-activating signal transduction; GO:0002449 lymphocyte mediated immunity; GO:0009987 cellular process; GO:0050778 positive regulation of immune response; GO:0009617 response to bacterium; GO:0002253 activation of immune response; GO:0006950 response to stress; GO:0042742 defense response to bacterium; GO:0016192 vesicle-mediated transport; GO:0072376 protein activation cascade; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0002696 positive regulation of leukocyte activation; GO:0061024 membrane organization; GO:0002684 positive regulation of immune system process; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0006955 immune response; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005615 extracellular space; GO:0009897 external side of plasma membrane; GO:0071944 cell periphery; GO:0042571 immunoglobulin complex, circulating; GO:0019814 immunoglobulin complex; GO:0032991 macromolecular complex; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0072562 blood microparticle; GO:0044459 plasma membrane part; GO:0044464 cell part; GO:0044425 membrane part; GO:0009986 cell surface; GO:0043234 protein complex; GO:0098552 side of membrane; ","GO:0034987 immunoglobulin receptor binding; GO:0005515 protein binding; GO:0005102 receptor binding; GO:0003823 antigen binding; GO:0005488 binding; ",{"$nulls":3},"IPR007110; IPR013783; IPR013106; ","Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin V-set domain; \r"]
["A0A0B4J1U7","Immunoglobulin heavy variable 6-1 OS=Homo sapiens OX=9606 GN=IGHV6-1","IGHV6-1",13.481,3.3402,13.2,2,4,2,0.925,0.921,0.9,1.095,1.034,1.125,1.185,0.003,"extracellular\r","GO:0044700 single organism signaling; GO:0002694 regulation of leukocyte activation; GO:0016064 immunoglobulin mediated immune response; GO:0007166 cell surface receptor signaling pathway; GO:0098542 defense response to other organism; GO:0044699 single-organism process; GO:0051249 regulation of lymphocyte activation; GO:0009607 response to biotic stimulus; GO:0051234 establishment of localization; GO:0006909 phagocytosis; GO:0009605 response to external stimulus; GO:0006956 complement activation; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0007154 cell communication; GO:0002250 adaptive immune response; GO:0006958 complement activation, classical pathway; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0050851 antigen receptor-mediated signaling pathway; GO:0044765 single-organism transport; GO:0051716 cellular response to stimulus; GO:0006911 phagocytosis, engulfment; GO:0006910 phagocytosis, recognition; GO:0002443 leukocyte mediated immunity; GO:0050864 regulation of B cell activation; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0051251 positive regulation of lymphocyte activation; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0051704 multi-organism process; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0050776 regulation of immune response; GO:0050853 B cell receptor signaling pathway; GO:0006810 transport; GO:0050865 regulation of cell activation; GO:0050789 regulation of biological process; GO:0048583 regulation of response to stimulus; GO:0002682 regulation of immune system process; GO:0006952 defense response; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0002252 immune effector process; GO:0010324 membrane invagination; GO:0006959 humoral immune response; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0008037 cell recognition; GO:0051707 response to other organism; GO:0045087 innate immune response; GO:0019724 B cell mediated immunity; GO:0071704 organic substance metabolic process; GO:0099024 plasma membrane invagination; GO:0050867 positive regulation of cell activation; GO:1902578 single-organism localization; GO:0050871 positive regulation of B cell activation; GO:0002757 immune response-activating signal transduction; GO:0002449 lymphocyte mediated immunity; GO:0009987 cellular process; GO:0050778 positive regulation of immune response; GO:0009617 response to bacterium; GO:0002253 activation of immune response; GO:0006950 response to stress; GO:0042742 defense response to bacterium; GO:0016192 vesicle-mediated transport; GO:0072376 protein activation cascade; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0002696 positive regulation of leukocyte activation; GO:0061024 membrane organization; GO:0002684 positive regulation of immune system process; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0006955 immune response; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005615 extracellular space; GO:0009897 external side of plasma membrane; GO:0071944 cell periphery; GO:0042571 immunoglobulin complex, circulating; GO:0019814 immunoglobulin complex; GO:0032991 macromolecular complex; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0072562 blood microparticle; GO:0044459 plasma membrane part; GO:0044464 cell part; GO:0044425 membrane part; GO:0009986 cell surface; GO:0043234 protein complex; GO:0098552 side of membrane; ","GO:0034987 immunoglobulin receptor binding; GO:0005515 protein binding; GO:0005102 receptor binding; GO:0003823 antigen binding; GO:0005488 binding; ",{"$nulls":3},"IPR007110; IPR013783; IPR013106; ","Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin V-set domain; \r"]
["A0A0B4J1V2","Immunoglobulin heavy variable 2-26 OS=Homo sapiens OX=9606 GN=IGHV2-26","IGHV2-26",13.182,9.5666,11.8,1,1,1,1.141,0.949,1.214,0.932,1.008,0.773,0.821,0.141,"extracellular\r","GO:0044700 single organism signaling; GO:0002694 regulation of leukocyte activation; GO:0016064 immunoglobulin mediated immune response; GO:0007166 cell surface receptor signaling pathway; GO:0098542 defense response to other organism; GO:0044699 single-organism process; GO:0051249 regulation of lymphocyte activation; GO:0009607 response to biotic stimulus; GO:0051234 establishment of localization; GO:0006909 phagocytosis; GO:0006956 complement activation; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0002250 adaptive immune response; GO:0006958 complement activation, classical pathway; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0050851 antigen receptor-mediated signaling pathway; GO:0044765 single-organism transport; GO:0051716 cellular response to stimulus; GO:0006911 phagocytosis, engulfment; GO:0002443 leukocyte mediated immunity; GO:0006910 phagocytosis, recognition; GO:0050864 regulation of B cell activation; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0051251 positive regulation of lymphocyte activation; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0050853 B cell receptor signaling pathway; GO:0006810 transport; GO:0050865 regulation of cell activation; GO:0050789 regulation of biological process; GO:0048583 regulation of response to stimulus; GO:0002682 regulation of immune system process; GO:0006952 defense response; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0002252 immune effector process; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0010324 membrane invagination; GO:0006959 humoral immune response; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0008037 cell recognition; GO:0051707 response to other organism; GO:0045087 innate immune response; GO:0071704 organic substance metabolic process; GO:0019724 B cell mediated immunity; GO:0099024 plasma membrane invagination; GO:0050867 positive regulation of cell activation; GO:1902578 single-organism localization; GO:0050871 positive regulation of B cell activation; GO:0002757 immune response-activating signal transduction; GO:0002449 lymphocyte mediated immunity; GO:0009987 cellular process; GO:0050778 positive regulation of immune response; GO:0009617 response to bacterium; GO:0002253 activation of immune response; GO:0006950 response to stress; GO:0042742 defense response to bacterium; GO:0016192 vesicle-mediated transport; GO:0072376 protein activation cascade; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0002696 positive regulation of leukocyte activation; GO:0061024 membrane organization; GO:0002684 positive regulation of immune system process; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0006955 immune response; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005615 extracellular space; GO:0009897 external side of plasma membrane; GO:0071944 cell periphery; GO:0042571 immunoglobulin complex, circulating; GO:0019814 immunoglobulin complex; GO:0032991 macromolecular complex; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0072562 blood microparticle; GO:0044459 plasma membrane part; GO:0044464 cell part; GO:0044425 membrane part; GO:0009986 cell surface; GO:0043234 protein complex; GO:0098552 side of membrane; ","GO:0034987 immunoglobulin receptor binding; GO:0005515 protein binding; GO:0005102 receptor binding; GO:0003823 antigen binding; GO:0005488 binding; ",{"$nulls":3},"IPR007110; IPR013783; IPR013106; ","Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin V-set domain; \r"]
["A0A0C4DH25","Immunoglobulin kappa variable 3D-20 OS=Homo sapiens OX=9606 GN=IGKV3D-20","IGKV3D-20",12.515,43.788,27.6,3,8,1,1.029,0.952,0.937,1.075,0.939,1.076,1.059,0.355,"extracellular\r","GO:0044700 single organism signaling; GO:0016064 immunoglobulin mediated immune response; GO:0051674 localization of cell; GO:0007166 cell surface receptor signaling pathway; GO:0038094 Fc-gamma receptor signaling pathway; GO:0044699 single-organism process; GO:0006909 phagocytosis; GO:0051234 establishment of localization; GO:0006956 complement activation; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0007154 cell communication; GO:0002250 adaptive immune response; GO:0006958 complement activation, classical pathway; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0044765 single-organism transport; GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0044763 single-organism cellular process; GO:0048870 cell motility; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0050900 leukocyte migration; GO:0002440 production of molecular mediator of immune response; GO:0048583 regulation of response to stimulus; GO:0002682 regulation of immune system process; GO:0002431 Fc receptor mediated stimulatory signaling pathway; GO:0040011 locomotion; GO:0050794 regulation of cellular process; GO:0016477 cell migration; GO:0002252 immune effector process; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0006959 humoral immune response; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0019724 B cell mediated immunity; GO:1902578 single-organism localization; GO:0002757 immune response-activating signal transduction; GO:0006508 proteolysis; GO:0006898 receptor-mediated endocytosis; GO:0002449 lymphocyte mediated immunity; GO:0038093 Fc receptor signaling pathway; GO:0050778 positive regulation of immune response; GO:0009987 cellular process; GO:0002253 activation of immune response; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0072376 protein activation cascade; GO:0044238 primary metabolic process; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0002377 immunoglobulin production; GO:0002684 positive regulation of immune system process; GO:0038095 Fc-epsilon receptor signaling pathway; GO:0006928 movement of cell or subcellular component; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis; GO:0051179 localization; GO:0006955 immune response; GO:0048584 positive regulation of response to stimulus; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0071944 cell periphery; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; ","GO:0004252 serine-type endopeptidase activity; GO:0004175 endopeptidase activity; GO:0008233 peptidase activity; GO:0003824 catalytic activity; GO:0017171 serine hydrolase activity; GO:0005488 binding; GO:0008236 serine-type peptidase activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0003823 antigen binding; ",{"$nulls":3},"IPR007110; IPR013783; IPR013106; IPR003599; ","Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin V-set domain; Immunoglobulin subtype; \r"]
["A0A0C4DH29","Immunoglobulin heavy variable 1-3 OS=Homo sapiens OX=9606 GN=IGHV1-3","IGHV1-3",13.008,7.8788,22.2,2,4,1,0.994,0.952,1.005,0.992,1.065,0.996,1.035,0.3,"extracellular\r","GO:0044700 single organism signaling; GO:0002694 regulation of leukocyte activation; GO:0016064 immunoglobulin mediated immune response; GO:0007166 cell surface receptor signaling pathway; GO:0098542 defense response to other organism; GO:0044699 single-organism process; GO:0051249 regulation of lymphocyte activation; GO:0009607 response to biotic stimulus; GO:0051234 establishment of localization; GO:0006909 phagocytosis; GO:0006956 complement activation; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0002250 adaptive immune response; GO:0006958 complement activation, classical pathway; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0050851 antigen receptor-mediated signaling pathway; GO:0044765 single-organism transport; GO:0051716 cellular response to stimulus; GO:0006911 phagocytosis, engulfment; GO:0002443 leukocyte mediated immunity; GO:0006910 phagocytosis, recognition; GO:0050864 regulation of B cell activation; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0051251 positive regulation of lymphocyte activation; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0050853 B cell receptor signaling pathway; GO:0006810 transport; GO:0050865 regulation of cell activation; GO:0050789 regulation of biological process; GO:0048583 regulation of response to stimulus; GO:0002682 regulation of immune system process; GO:0006952 defense response; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0002252 immune effector process; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0010324 membrane invagination; GO:0006959 humoral immune response; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0008037 cell recognition; GO:0051707 response to other organism; GO:0045087 innate immune response; GO:0071704 organic substance metabolic process; GO:0019724 B cell mediated immunity; GO:0099024 plasma membrane invagination; GO:0050867 positive regulation of cell activation; GO:1902578 single-organism localization; GO:0050871 positive regulation of B cell activation; GO:0002757 immune response-activating signal transduction; GO:0002449 lymphocyte mediated immunity; GO:0009987 cellular process; GO:0050778 positive regulation of immune response; GO:0009617 response to bacterium; GO:0002253 activation of immune response; GO:0006950 response to stress; GO:0042742 defense response to bacterium; GO:0016192 vesicle-mediated transport; GO:0072376 protein activation cascade; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0002696 positive regulation of leukocyte activation; GO:0061024 membrane organization; GO:0002684 positive regulation of immune system process; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0006955 immune response; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005615 extracellular space; GO:0009897 external side of plasma membrane; GO:0071944 cell periphery; GO:0042571 immunoglobulin complex, circulating; GO:0019814 immunoglobulin complex; GO:0032991 macromolecular complex; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0072562 blood microparticle; GO:0044459 plasma membrane part; GO:0044464 cell part; GO:0044425 membrane part; GO:0009986 cell surface; GO:0043234 protein complex; GO:0098552 side of membrane; ","GO:0034987 immunoglobulin receptor binding; GO:0005515 protein binding; GO:0005102 receptor binding; GO:0003823 antigen binding; GO:0005488 binding; ",{"$nulls":3},"IPR007110; IPR013783; IPR013106; ","Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin V-set domain; \r"]
["A0A0C4DH34","Immunoglobulin heavy variable 4-28 OS=Homo sapiens OX=9606 GN=IGHV4-28","IGHV4-28",13.124,2.5471,7.7,1,2,1,0.924,0.986,1.014,0.998,1.095,0.986,1.053,0.299,"extracellular\r","GO:0044700 single organism signaling; GO:0002694 regulation of leukocyte activation; GO:0016064 immunoglobulin mediated immune response; GO:0007166 cell surface receptor signaling pathway; GO:0098542 defense response to other organism; GO:0044699 single-organism process; GO:0051249 regulation of lymphocyte activation; GO:0009607 response to biotic stimulus; GO:0051234 establishment of localization; GO:0006909 phagocytosis; GO:0009605 response to external stimulus; GO:0006956 complement activation; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0007154 cell communication; GO:0002250 adaptive immune response; GO:0006958 complement activation, classical pathway; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0050851 antigen receptor-mediated signaling pathway; GO:0044765 single-organism transport; GO:0051716 cellular response to stimulus; GO:0006911 phagocytosis, engulfment; GO:0006910 phagocytosis, recognition; GO:0002443 leukocyte mediated immunity; GO:0050864 regulation of B cell activation; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0051251 positive regulation of lymphocyte activation; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0051704 multi-organism process; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0050776 regulation of immune response; GO:0050853 B cell receptor signaling pathway; GO:0006810 transport; GO:0050865 regulation of cell activation; GO:0050789 regulation of biological process; GO:0048583 regulation of response to stimulus; GO:0002682 regulation of immune system process; GO:0006952 defense response; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0002252 immune effector process; GO:0010324 membrane invagination; GO:0006959 humoral immune response; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0008037 cell recognition; GO:0051707 response to other organism; GO:0045087 innate immune response; GO:0019724 B cell mediated immunity; GO:0071704 organic substance metabolic process; GO:0099024 plasma membrane invagination; GO:0050867 positive regulation of cell activation; GO:1902578 single-organism localization; GO:0050871 positive regulation of B cell activation; GO:0002757 immune response-activating signal transduction; GO:0002449 lymphocyte mediated immunity; GO:0009987 cellular process; GO:0050778 positive regulation of immune response; GO:0009617 response to bacterium; GO:0002253 activation of immune response; GO:0006950 response to stress; GO:0042742 defense response to bacterium; GO:0016192 vesicle-mediated transport; GO:0072376 protein activation cascade; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0002696 positive regulation of leukocyte activation; GO:0061024 membrane organization; GO:0002684 positive regulation of immune system process; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0006955 immune response; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005615 extracellular space; GO:0009897 external side of plasma membrane; GO:0071944 cell periphery; GO:0042571 immunoglobulin complex, circulating; GO:0019814 immunoglobulin complex; GO:0032991 macromolecular complex; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0072562 blood microparticle; GO:0044459 plasma membrane part; GO:0044464 cell part; GO:0044425 membrane part; GO:0009986 cell surface; GO:0043234 protein complex; GO:0098552 side of membrane; ","GO:0034987 immunoglobulin receptor binding; GO:0005515 protein binding; GO:0005102 receptor binding; GO:0003823 antigen binding; GO:0005488 binding; ","K06856","IGH; immunoglobulin heavy chain","hsa05330 Allograft rejection - Homo sapiens (human); hsa05322 Systemic lupus erythematosus - Homo sapiens (human); hsa04672 Intestinal immune network for IgA production - Homo sapiens (human); hsa04072 Phospholipase D signaling pathway - Homo sapiens (human); hsa05152 Tuberculosis - Homo sapiens (human); hsa05150 Staphylococcus aureus infection - Homo sapiens (human); hsa04650 Natural killer cell mediated cytotoxicity - Homo sapiens (human); hsa05323 Rheumatoid arthritis - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); hsa04662 B cell receptor signaling pathway - Homo sapiens (human); hsa05140 Leishmaniasis - Homo sapiens (human); hsa04640 Hematopoietic cell lineage - Homo sapiens (human); hsa04020 Calcium signaling pathway - Homo sapiens (human); hsa05162 Measles - Homo sapiens (human); hsa05340 Primary immunodeficiency - Homo sapiens (human); hsa05320 Autoimmune thyroid disease - Homo sapiens (human); hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human); hsa04666 Fc gamma R-mediated phagocytosis - Homo sapiens (human); hsa04664 Fc epsilon RI signaling pathway - Homo sapiens (human); hsa05414 Dilated cardiomyopathy (DCM) - Homo sapiens (human); hsa05310 Asthma - Homo sapiens (human); hsa05416 Viral myocarditis - Homo sapiens (human); hsa05146 Amoebiasis - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); hsa05143 African trypanosomiasis - Homo sapiens (human); hsa04064 NF-kappa B signaling pathway - Homo sapiens (human); ","IPR007110; IPR013783; IPR013106; ","Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin V-set domain; \r"]
["A0A0C4DH38","Immunoglobulin heavy variable 5-51 OS=Homo sapiens OX=9606 GN=IGHV5-51","IGHV5-51",12.674,31.542,35.9,3,4,2,0.749,1.066,0.774,1.302,1.098,1.016,1.319,0.101,"extracellular\r","GO:0044700 single organism signaling; GO:0002694 regulation of leukocyte activation; GO:0016064 immunoglobulin mediated immune response; GO:0007166 cell surface receptor signaling pathway; GO:0098542 defense response to other organism; GO:0044699 single-organism process; GO:0051249 regulation of lymphocyte activation; GO:0009607 response to biotic stimulus; GO:0051234 establishment of localization; GO:0006909 phagocytosis; GO:0009605 response to external stimulus; GO:0006956 complement activation; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0007154 cell communication; GO:0002250 adaptive immune response; GO:0006958 complement activation, classical pathway; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0050851 antigen receptor-mediated signaling pathway; GO:0044765 single-organism transport; GO:0051716 cellular response to stimulus; GO:0006911 phagocytosis, engulfment; GO:0006910 phagocytosis, recognition; GO:0002443 leukocyte mediated immunity; GO:0050864 regulation of B cell activation; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0051251 positive regulation of lymphocyte activation; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0051704 multi-organism process; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0050776 regulation of immune response; GO:0050853 B cell receptor signaling pathway; GO:0006810 transport; GO:0050865 regulation of cell activation; GO:0050789 regulation of biological process; GO:0048583 regulation of response to stimulus; GO:0002682 regulation of immune system process; GO:0006952 defense response; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0002252 immune effector process; GO:0010324 membrane invagination; GO:0006959 humoral immune response; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0008037 cell recognition; GO:0051707 response to other organism; GO:0045087 innate immune response; GO:0019724 B cell mediated immunity; GO:0071704 organic substance metabolic process; GO:0099024 plasma membrane invagination; GO:0050867 positive regulation of cell activation; GO:1902578 single-organism localization; GO:0050871 positive regulation of B cell activation; GO:0002757 immune response-activating signal transduction; GO:0002449 lymphocyte mediated immunity; GO:0009987 cellular process; GO:0050778 positive regulation of immune response; GO:0009617 response to bacterium; GO:0002253 activation of immune response; GO:0006950 response to stress; GO:0042742 defense response to bacterium; GO:0016192 vesicle-mediated transport; GO:0072376 protein activation cascade; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0002696 positive regulation of leukocyte activation; GO:0061024 membrane organization; GO:0002684 positive regulation of immune system process; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0006955 immune response; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005615 extracellular space; GO:0009897 external side of plasma membrane; GO:0071944 cell periphery; GO:0042571 immunoglobulin complex, circulating; GO:0019814 immunoglobulin complex; GO:0032991 macromolecular complex; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0072562 blood microparticle; GO:0044459 plasma membrane part; GO:0044464 cell part; GO:0044425 membrane part; GO:0009986 cell surface; GO:0043234 protein complex; GO:0098552 side of membrane; ","GO:0034987 immunoglobulin receptor binding; GO:0005515 protein binding; GO:0005102 receptor binding; GO:0003823 antigen binding; GO:0005488 binding; ",{"$nulls":3},"IPR007110; IPR013783; IPR013106; ","Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin V-set domain; \r"]
["A0A0C4DH72","Immunoglobulin kappa variable 1-6 OS=Homo sapiens OX=9606 GN=IGKV1-6","IGKV1-6",12.697,7.1136,10.3,1,2,1,1.078,1.033,1.086,0.892,0.928,0.996,0.881,0.0235,"extracellular\r","GO:0002376 immune system process; GO:0002377 immunoglobulin production; GO:0002440 production of molecular mediator of immune response; GO:0006955 immune response; GO:0050896 response to stimulus; GO:0002250 adaptive immune response; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0071944 cell periphery; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; ","GO:0005515 protein binding; GO:0003823 antigen binding; GO:0005488 binding; ",{"$nulls":3},"IPR007110; IPR013783; IPR003599; IPR013106; ","Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin subtype; Immunoglobulin V-set domain; \r"]
["A0AVT1","Ubiquitin-like modifier-activating enzyme 6 OS=Homo sapiens OX=9606 GN=UBA6","UBA6",117.97,53.93,14,12,12,12,0.97,0.971,1.032,1.009,1.021,1.021,1.026,0.276,"nucleus\r","GO:0021766 hippocampus development; GO:0007420 brain development; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0021764 amygdala development; GO:0021761 limbic system development; GO:0044237 cellular metabolic process; GO:0050877 neurological system process; GO:0007610 behavior; GO:0021537 telencephalon development; GO:0008152 metabolic process; GO:0060322 head development; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0032501 multicellular organismal process; GO:1901575 organic substance catabolic process; GO:0048513 animal organ development; GO:0007612 learning; GO:0030030 cell projection organization; GO:0030163 protein catabolic process; GO:0007417 central nervous system development; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0044708 single-organism behavior; GO:0021543 pallium development; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0016358 dendrite development; GO:0044257 cellular protein catabolic process; GO:0044267 cellular protein metabolic process; GO:0048468 cell development; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0050890 cognition; GO:0044248 cellular catabolic process; GO:0030900 forebrain development; GO:0006508 proteolysis; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0043632 modification-dependent macromolecule catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0003008 system process; GO:0016567 protein ubiquitination; GO:0019941 modification-dependent protein catabolic process; GO:0048731 system development; GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0044238 primary metabolic process; GO:0031175 neuron projection development; GO:0007611 learning or memory; GO:0030182 neuron differentiation; GO:0032446 protein modification by small protein conjugation; GO:0060996 dendritic spine development; GO:0044767 single-organism developmental process; GO:0009057 macromolecule catabolic process; GO:0007626 locomotory behavior; GO:0043412 macromolecule modification; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0044444 cytoplasmic part; ","GO:0008641 small protein activating enzyme activity; GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0004839 ubiquitin activating enzyme activity; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016874 ligase activity; GO:0005515 protein binding; GO:0016877 ligase activity, forming carbon-sulfur bonds; GO:0019780 FAT10 activating enzyme activity; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K10699","UBE1L2; ubiquitin-activating enzyme E1-like protein 2 [EC:6.2.1.45]","hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human); ","IPR019572; IPR032418; IPR000594; IPR016040; IPR032420; IPR018965; ","\"Ubiquitin-activating enzyme, catalytic cysteine domain; Ubiquitin-activating enzyme E1, FCCH domain; THIF-type NAD/FAD binding fold; NAD(P)-binding domain; Ubiquitin-activating enzyme E1, four-helix bundle; Ubiquitin-activating enzyme E1, C-terminal; \"\r"]
["A0FGR8","Extended synaptotagmin-2 OS=Homo sapiens OX=9606 GN=ESYT2","ESYT2",102.36,77.064,19,13,18,13,1.027,1.067,1.063,0.964,0.967,0.931,0.907,0.00466,"nucleus\r","GO:1903509 liposaccharide metabolic process; GO:0006869 lipid transport; GO:0006643 membrane lipid metabolic process; GO:0016192 vesicle-mediated transport; GO:0006687 glycosphingolipid metabolic process; GO:0006664 glycolipid metabolic process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0010876 lipid localization; GO:0071702 organic substance transport; GO:0006897 endocytosis; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0051234 establishment of localization; GO:0006810 transport; GO:0008152 metabolic process; GO:1902578 single-organism localization; GO:0044710 single-organism metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0006665 sphingolipid metabolic process; GO:0051179 localization; GO:0033036 macromolecule localization; GO:0009987 cellular process; GO:0006629 lipid metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0044765 single-organism transport; ","GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0019898 extrinsic component of membrane; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0031234 extrinsic component of cytoplasmic side of plasma membrane; GO:0005623 cell; GO:0009898 cytoplasmic side of plasma membrane; GO:0098562 cytoplasmic side of membrane; GO:0044422 organelle part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0031227 intrinsic component of endoplasmic reticulum membrane; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044232 organelle membrane contact site; GO:0098552 side of membrane; GO:0043229 intracellular organelle; GO:0031226 intrinsic component of plasma membrane; GO:0044446 intracellular organelle part; GO:0019897 extrinsic component of plasma membrane; GO:0012505 endomembrane system; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044459 plasma membrane part; GO:0044432 endoplasmic reticulum part; GO:0044444 cytoplasmic part; ","GO:0005544 calcium-dependent phospholipid binding; GO:0070405 ammonium ion binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0031210 phosphatidylcholine binding; GO:0050839 cell adhesion molecule binding; GO:0050997 quaternary ammonium group binding; GO:0042802 identical protein binding; GO:0005488 binding; GO:0005543 phospholipid binding; GO:0045296 cadherin binding; GO:0035091 phosphatidylinositol binding; GO:0008289 lipid binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0008429 phosphatidylethanolamine binding; GO:0005509 calcium ion binding; ",{"$nulls":3},"IPR031468; IPR000008; ","Synaptotagmin-like mitochondrial-lipid-binding domain; C2 domain; \r"]
["A0MZ66","Shootin-1 OS=Homo sapiens OX=9606 GN=SHTN1","SHTN1",71.639,37.472,20.3,13,15,13,0.879,0.966,0.939,1.058,1.081,1.064,1.151,0.00798,"nucleus\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0030335 positive regulation of cell migration; GO:0065008 regulation of biological quality; GO:0007166 cell surface receptor signaling pathway; GO:0032989 cellular component morphogenesis; GO:0045927 positive regulation of growth; GO:0001558 regulation of cell growth; GO:0060327 cytoplasmic actin-based contraction involved in cell motility; GO:0030036 actin cytoskeleton organization; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0032535 regulation of cellular component size; GO:0006930 substrate-dependent cell migration, cell extension; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0030307 positive regulation of cell growth; GO:0031346 positive regulation of cell projection organization; GO:0048699 generation of neurons; GO:0045773 positive regulation of axon extension; GO:0044763 single-organism cellular process; GO:0048812 neuron projection morphogenesis; GO:0051272 positive regulation of cellular component movement; GO:0007264 small GTPase mediated signal transduction; GO:0007163 establishment or maintenance of cell polarity; GO:0048870 cell motility; GO:0032501 multicellular organismal process; GO:0000902 cell morphogenesis; GO:2000114 regulation of establishment of cell polarity; GO:0051094 positive regulation of developmental process; GO:0097435 supramolecular fiber organization; GO:0010975 regulation of neuron projection development; GO:0070650 actin filament bundle distribution; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:2000147 positive regulation of cell motility; GO:0051239 regulation of multicellular organismal process; GO:0045597 positive regulation of cell differentiation; GO:0009653 anatomical structure morphogenesis; GO:0050772 positive regulation of axonogenesis; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:2000145 regulation of cell motility; GO:0007409 axonogenesis; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0051960 regulation of nervous system development; GO:0060284 regulation of cell development; GO:0030334 regulation of cell migration; GO:0050770 regulation of axonogenesis; GO:0030031 cell projection assembly; GO:0061572 actin filament bundle organization; GO:0030182 neuron differentiation; GO:0030516 regulation of axon extension; GO:0010976 positive regulation of neuron projection development; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0061387 regulation of extent of cell growth; GO:0006928 movement of cell or subcellular component; GO:2001222 regulation of neuron migration; GO:0050769 positive regulation of neurogenesis; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:2001224 positive regulation of neuron migration; GO:0030048 actin filament-based movement; GO:0010256 endomembrane system organization; GO:0070252 actin-mediated cell contraction; GO:0045666 positive regulation of neuron differentiation; GO:0051674 localization of cell; GO:0040017 positive regulation of locomotion; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0051130 positive regulation of cellular component organization; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0032990 cell part morphogenesis; GO:0022607 cellular component assembly; GO:0048858 cell projection morphogenesis; GO:0007266 Rho protein signal transduction; GO:0006929 substrate-dependent cell migration; GO:0010720 positive regulation of cell development; GO:0032502 developmental process; GO:0048639 positive regulation of developmental growth; GO:0032878 regulation of establishment or maintenance of cell polarity; GO:0051962 positive regulation of nervous system development; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0038007 netrin-activated signaling pathway; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0030030 cell projection organization; GO:0045664 regulation of neuron differentiation; GO:0040011 locomotion; GO:0048856 anatomical structure development; GO:0007265 Ras protein signal transduction; GO:0007029 endoplasmic reticulum organization; GO:2000026 regulation of multicellular organismal development; GO:0016477 cell migration; GO:0016043 cellular component organization; GO:0061163 endoplasmic reticulum polarization; GO:0040008 regulation of growth; GO:0007015 actin filament organization; GO:0010770 positive regulation of cell morphogenesis involved in differentiation; GO:0031344 regulation of cell projection organization; GO:0048638 regulation of developmental growth; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0000904 cell morphogenesis involved in differentiation; GO:0030154 cell differentiation; GO:0008361 regulation of cell size; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0061573 actin filament bundle retrograde transport; GO:0035556 intracellular signal transduction; GO:0031175 neuron projection development; GO:0048518 positive regulation of biological process; GO:0032488 Cdc42 protein signal transduction; GO:0061564 axon development; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0090066 regulation of anatomical structure size; GO:0051128 regulation of cellular component organization; GO:0040012 regulation of locomotion; GO:0022604 regulation of cell morphogenesis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:0050767 regulation of neurogenesis; ","GO:0005874 microtubule; GO:0005737 cytoplasm; GO:0043025 neuronal cell body; GO:0032991 macromolecular complex; GO:0030426 growth cone; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0098858 actin-based cell projection; GO:0005623 cell; GO:0099080 supramolecular complex; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0030027 lamellipodium; GO:0030175 filopodium; GO:0048471 perinuclear region of cytoplasm; GO:0043005 neuron projection; GO:0097458 neuron part; GO:0043229 intracellular organelle; GO:0031252 cell leading edge; GO:0099513 polymeric cytoskeletal fiber; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0005875 microtubule associated complex; GO:0030427 site of polarized growth; GO:0044463 cell projection part; GO:0033267 axon part; GO:0099081 supramolecular polymer; GO:0030424 axon; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0044295 axonal growth cone; GO:0043204 perikaryon; GO:0044297 cell body; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0051015 actin filament binding; GO:0050839 cell adhesion molecule binding; GO:0008092 cytoskeletal protein binding; GO:0019894 kinesin binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0044877 macromolecular complex binding; GO:0003779 actin binding; GO:0005515 protein binding; GO:0032403 protein complex binding; "]
["A1IGU5","Rho guanine nucleotide exchange factor 37 OS=Homo sapiens OX=9606 GN=ARHGEF37","ARHGEF37",76.277,2.2304,1.3,1,1,1,1.139,1.191,0.813,0.836,0.913,1.125,0.914,0.606,"cyto_nucl\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0051716 cellular response to stimulus; GO:1902531 regulation of intracellular signal transduction; GO:0043547 positive regulation of GTPase activity; GO:0035556 intracellular signal transduction; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0046578 regulation of Ras protein signal transduction; GO:0007264 small GTPase mediated signal transduction; GO:0023052 signaling; GO:0050896 response to stimulus; GO:0043085 positive regulation of catalytic activity; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0050789 regulation of biological process; GO:0007154 cell communication; GO:0051336 regulation of hydrolase activity; GO:0051345 positive regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0044093 positive regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0065009 regulation of molecular function; GO:0009966 regulation of signal transduction; GO:0035023 regulation of Rho protein signal transduction; GO:0009987 cellular process; GO:0051056 regulation of small GTPase mediated signal transduction; GO:0065007 biological regulation; ","GO:0044424 intracellular part; GO:0005623 cell; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; ","GO:0005088 Ras guanyl-nucleotide exchange factor activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0005085 guanyl-nucleotide exchange factor activity; GO:0005488 binding; GO:0005089 Rho guanyl-nucleotide exchange factor activity; ","K20710",null,null,"IPR011511; IPR001452; IPR027267; IPR004148; IPR000219; ","Variant SH3 domain; SH3 domain; Arfaptin homology (AH) domain/BAR domain; BAR domain; Dbl homology (DH) domain; \r"]
["A1L0T0","Acetolactate synthase-like protein OS=Homo sapiens OX=9606 GN=ILVBL","ILVBL",67.867,80.297,18.7,8,12,8,0.971,0.998,0.969,1.04,0.989,1.102,1.066,0.127,"endoplasmic reticulum\r",null,"GO:0031224 intrinsic component of membrane; GO:0016020 membrane; GO:0016021 integral component of membrane; GO:0044425 membrane part; ","GO:0000287 magnesium ion binding; GO:0019842 vitamin binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0048037 cofactor binding; GO:1901681 sulfur compound binding; GO:0030976 thiamine pyrophosphate binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0043168 anion binding; GO:0016740 transferase activity; GO:0036094 small molecule binding; GO:0050662 coenzyme binding; ","K11259",null,null,"IPR012000; IPR029035; IPR029061; IPR011766; IPR012001; ","\"Thiamine pyrophosphate enzyme, central domain; DHS-like NAD/FAD-binding domain; Thiamin diphosphate-binding fold; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; \"\r"]
["A1L4H1","Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D OS=Homo sapiens OX=9606 GN=SSC5D","SSC5D",165.74,80.429,11.4,12,16,12,1.184,1.182,1.172,0.849,0.828,0.788,0.697,0.00372,"extracellular\r","GO:0009593 detection of chemical stimulus; GO:0098542 defense response to other organism; GO:0044699 single-organism process; GO:0051241 negative regulation of multicellular organismal process; GO:0051046 regulation of secretion; GO:0098581 detection of external biotic stimulus; GO:0001818 negative regulation of cytokine production; GO:0050710 negative regulation of cytokine secretion; GO:0051234 establishment of localization; GO:0009607 response to biotic stimulus; GO:0009605 response to external stimulus; GO:2000483 negative regulation of interleukin-8 secretion; GO:0032879 regulation of localization; GO:0051606 detection of stimulus; GO:0032502 developmental process; GO:0051051 negative regulation of transport; GO:0050709 negative regulation of protein secretion; GO:0050829 defense response to Gram-negative bacterium; GO:0002237 response to molecule of bacterial origin; GO:1903531 negative regulation of secretion by cell; GO:0016045 detection of bacterium; GO:0050707 regulation of cytokine secretion; GO:1903530 regulation of secretion by cell; GO:0032501 multicellular organismal process; GO:0050830 defense response to Gram-positive bacterium; GO:0051704 multi-organism process; GO:0006810 transport; GO:2000482 regulation of interleukin-8 secretion; GO:0051048 negative regulation of secretion; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0051223 regulation of protein transport; GO:0006952 defense response; GO:0048856 anatomical structure development; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0032677 regulation of interleukin-8 production; GO:0043207 response to external biotic stimulus; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0045087 innate immune response; GO:0070201 regulation of establishment of protein localization; GO:0051239 regulation of multicellular organismal process; GO:0032490 detection of molecule of bacterial origin; GO:0032493 response to bacterial lipoprotein; GO:0007275 multicellular organism development; GO:0032880 regulation of protein localization; GO:0006898 receptor-mediated endocytosis; GO:0050708 regulation of protein secretion; GO:0032717 negative regulation of interleukin-8 production; GO:0009617 response to bacterium; GO:0006950 response to stress; GO:0042742 defense response to bacterium; GO:0051224 negative regulation of protein transport; GO:0051049 regulation of transport; GO:0016192 vesicle-mediated transport; GO:0009595 detection of biotic stimulus; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0006897 endocytosis; GO:0042494 detection of bacterial lipoprotein; GO:0098543 detection of other organism; GO:0044767 single-organism developmental process; GO:0001817 regulation of cytokine production; GO:1904950 negative regulation of establishment of protein localization; GO:0006955 immune response; GO:0051179 localization; GO:0065007 biological regulation; ","GO:0031012 extracellular matrix; GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; ","GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0001968 fibronectin binding; GO:0043236 laminin binding; GO:0005488 binding; GO:0038024 cargo receptor activity; GO:0005515 protein binding; GO:0005044 scavenger receptor activity; GO:0050840 extracellular matrix binding; ",{"$nulls":3},"IPR001190; IPR017448; ","SRCR domain; SRCR-like domain; \r"]
["A1X283","SH3 and PX domain-containing protein 2B OS=Homo sapiens OX=9606 GN=SH3PXD2B","SH3PXD2B",101.58,13.538,7.9,5,5,5,0.914,0.941,0.99,1.093,0.989,1.074,1.109,0.0556,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:0006801 superoxide metabolic process; GO:0001649 osteoblast differentiation; GO:0065008 regulation of biological quality; GO:0022414 reproductive process; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0045927 positive regulation of growth; GO:0051130 positive regulation of cellular component organization; GO:0008152 metabolic process; GO:0007507 heart development; GO:0022607 cellular component assembly; GO:0051240 positive regulation of multicellular organismal process; GO:0009893 positive regulation of metabolic process; GO:0065003 macromolecular complex assembly; GO:0044093 positive regulation of molecular function; GO:0044706 multi-multicellular organism process; GO:0022617 extracellular matrix disassembly; GO:0051493 regulation of cytoskeleton organization; GO:0061448 connective tissue development; GO:0030198 extracellular matrix organization; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0040014 regulation of multicellular organism growth; GO:0048639 positive regulation of developmental growth; GO:0009888 tissue development; GO:0071822 protein complex subunit organization; GO:0072657 protein localization to membrane; GO:0001503 ossification; GO:0055114 oxidation-reduction process; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0071800 podosome assembly; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0010638 positive regulation of organelle organization; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0009887 animal organ morphogenesis; GO:0065009 regulation of molecular function; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:1902905 positive regulation of supramolecular fiber organization; GO:0032233 positive regulation of actin filament bundle assembly; GO:0070271 protein complex biogenesis; GO:0051094 positive regulation of developmental process; GO:0048609 multicellular organismal reproductive process; GO:0048856 anatomical structure development; GO:0001501 skeletal system development; GO:1902903 regulation of supramolecular fiber organization; GO:2000026 regulation of multicellular organismal development; GO:0000003 reproduction; GO:0072359 circulatory system development; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0040008 regulation of growth; GO:0032956 regulation of actin cytoskeleton organization; GO:0060255 regulation of macromolecule metabolic process; GO:0060378 regulation of brood size; GO:0044087 regulation of cellular component biogenesis; GO:0048638 regulation of developmental growth; GO:0051239 regulation of multicellular organismal process; GO:0045597 positive regulation of cell differentiation; GO:0009653 anatomical structure morphogenesis; GO:0001654 eye development; GO:0030154 cell differentiation; GO:0045600 positive regulation of fat cell differentiation; GO:0070925 organelle assembly; GO:0072593 reactive oxygen species metabolic process; GO:0010628 positive regulation of gene expression; GO:0043062 extracellular structure organization; GO:1904888 cranial skeletal system development; GO:1904177 regulation of adipose tissue development; GO:0007275 multicellular organism development; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0045595 regulation of cell differentiation; GO:0051495 positive regulation of cytoskeleton organization; GO:0032231 regulation of actin filament bundle assembly; GO:0048731 system development; GO:0033043 regulation of organelle organization; GO:0032970 regulation of actin filament-based process; GO:0048518 positive regulation of biological process; GO:0051492 regulation of stress fiber assembly; GO:0043933 macromolecular complex subunit organization; GO:0048705 skeletal system morphogenesis; GO:0043085 positive regulation of catalytic activity; GO:0051641 cellular localization; GO:0045165 cell fate commitment; GO:1904179 positive regulation of adipose tissue development; GO:0060348 bone development; GO:0032504 multicellular organism reproduction; GO:0045598 regulation of fat cell differentiation; GO:0070727 cellular macromolecule localization; GO:0060612 adipose tissue development; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0044703 multi-organism reproductive process; GO:0051496 positive regulation of stress fiber assembly; GO:0002051 osteoblast fate commitment; GO:0022411 cellular component disassembly; GO:0051128 regulation of cellular component organization; GO:0040018 positive regulation of multicellular organism growth; GO:0007423 sensory organ development; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0044089 positive regulation of cellular component biogenesis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0030054 cell junction; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0002102 podosome; GO:0005623 cell; GO:0015629 actin cytoskeleton; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0043226 organelle; GO:0005622 intracellular; GO:0044464 cell part; GO:0043234 protein complex; ","GO:1901981 phosphatidylinositol phosphate binding; GO:0043167 ion binding; GO:0080025 phosphatidylinositol-3,5-bisphosphate binding; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:1902936 phosphatidylinositol bisphosphate binding; GO:0030234 enzyme regulator activity; GO:0032266 phosphatidylinositol-3-phosphate binding; GO:0005488 binding; GO:0010314 phosphatidylinositol-5-phosphate binding; GO:0042169 SH2 domain binding; GO:0035091 phosphatidylinositol binding; GO:0005543 phospholipid binding; GO:0008289 lipid binding; GO:0016176 superoxide-generating NADPH oxidase activator activity; GO:0043168 anion binding; GO:0019904 protein domain specific binding; GO:0070273 phosphatidylinositol-4-phosphate binding; GO:0008047 enzyme activator activity; ",{"$nulls":3},"IPR011511; IPR001452; IPR001683; ","Variant SH3 domain; SH3 domain; Phox homologous domain; \r"]
["A1Z1Q3","O-acetyl-ADP-ribose deacetylase MACROD2 OS=Homo sapiens OX=9606 GN=MACROD2","MACROD2",50.05,3.4817,2.7,1,1,1,1,1.067,1.004,1.001,1.081,0.861,0.958,0.543,"nucleus\r","GO:0033554 cellular response to stress; GO:0044707 single-multicellular organism process; GO:0042278 purine nucleoside metabolic process; GO:0009116 nucleoside metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0007420 brain development; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0051725 protein de-ADP-ribosylation; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0060322 head development; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0006950 response to stress; GO:0048731 system development; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0072521 purine-containing compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:0032501 multicellular organismal process; GO:0006974 cellular response to DNA damage stimulus; GO:0048513 animal organ development; GO:0044767 single-organism developmental process; GO:0007417 central nervous system development; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:1901657 glycosyl compound metabolic process; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:0048856 anatomical structure development; GO:1901564 organonitrogen compound metabolic process; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005730 nucleolus; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005856 cytoskeleton; GO:0005815 microtubule organizing center; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0005813 centrosome; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0019213 deacetylase activity; GO:0016787 hydrolase activity; GO:0003824 catalytic activity; GO:0016798 hydrolase activity, acting on glycosyl bonds; ",{"$nulls":3},"IPR002589; ","Macro domain; \r"]
["A2RRP1","Neuroblastoma-amplified sequence OS=Homo sapiens OX=9606 GN=NBAS","NBAS",268.57,5.6378,1.2,3,3,3,0.971,0.972,1.153,0.961,1.036,0.915,0.941,0.43,"nucleus\r","GO:2000623 negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0044237 cellular metabolic process; GO:0051253 negative regulation of RNA metabolic process; GO:1903312 negative regulation of mRNA metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0009893 positive regulation of metabolic process; GO:1901361 organic cyclic compound catabolic process; GO:0043170 macromolecule metabolic process; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0010468 regulation of gene expression; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0016070 RNA metabolic process; GO:0006401 RNA catabolic process; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0016071 mRNA metabolic process; GO:0050794 regulation of cellular process; GO:1902369 negative regulation of RNA catabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0048193 Golgi vesicle transport; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0071704 organic substance metabolic process; GO:1902373 negative regulation of mRNA catabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0010628 positive regulation of gene expression; GO:0051171 regulation of nitrogen compound metabolic process; GO:0044248 cellular catabolic process; GO:0009895 negative regulation of catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0061013 regulation of mRNA catabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0016192 vesicle-mediated transport; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0045184 establishment of protein localization; GO:0031330 negative regulation of cellular catabolic process; GO:1903311 regulation of mRNA metabolic process; GO:0006890 retrograde vesicle-mediated transport, Golgi to ER; GO:0009057 macromolecule catabolic process; GO:0051179 localization; GO:0009056 catabolic process; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044432 endoplasmic reticulum part; GO:0044425 membrane part; GO:0070939 Dsl1/NZR complex; GO:0005622 intracellular; GO:0044464 cell part; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; GO:0099023 tethering complex; ","GO:0000149 SNARE binding; GO:0005515 protein binding; GO:0005488 binding; ","K20473",null,null,"IPR015943; IPR011044; IPR013244; IPR029145; ","\"WD40/YVTN repeat-like-containing domain; Quinoprotein amine dehydrogenase, beta chain-like; Sec39 domain; Neuroblastoma-amplified sequence, N-terminal; \"\r"]
["A3KMH1","von Willebrand factor A domain-containing protein 8 OS=Homo sapiens OX=9606 GN=VWA8","VWA8",214.82,14.26,2.3,4,4,4,1.062,0.907,0.85,0.85,1.04,1.283,1.126,0.469,"mitochondria\r",null,"GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0044444 cytoplasmic part; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0016887 ATPase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ",{"$nulls":3},"IPR003593; IPR011704; IPR027417; IPR002035; ","\"AAA+ ATPase domain; ATPase, dynein-related, AAA domain; P-loop containing nucleoside triphosphate hydrolase; von Willebrand factor, type A; \"\r"]
["A4D1P6","WD repeat-containing protein 91 OS=Homo sapiens OX=9606 GN=WDR91","WDR91",83.343,13.132,8.8,5,6,5,1.033,0.892,0.937,1.085,0.999,1.057,1.097,0.13,"nucleus\r",null,null,"GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR017986; IPR015943; ","WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain; \r"]
["A5YKK6","CCR4-NOT transcription complex subunit 1 OS=Homo sapiens OX=9606 GN=CNOT1","CNOT1",266.94,47,6.6,14,14,14,0.912,1.048,1.12,0.969,1.032,0.984,0.969,0.681,"cytoplasm\r","GO:0044700 single organism signaling; GO:1902807 negative regulation of cell cycle G1/S phase transition; GO:0097659 nucleic acid-templated transcription; GO:0010608 posttranscriptional regulation of gene expression; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0072431 signal transduction involved in mitotic G1 DNA damage checkpoint; GO:1902403 signal transduction involved in mitotic DNA integrity checkpoint; GO:0008152 metabolic process; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0043170 macromolecule metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0090068 positive regulation of cell cycle process; GO:0051716 cellular response to stimulus; GO:0000278 mitotic cell cycle; GO:0018130 heterocycle biosynthetic process; GO:0044773 mitotic DNA damage checkpoint; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:2000134 negative regulation of G1/S transition of mitotic cell cycle; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0000122 negative regulation of transcription from RNA polymerase II promoter; GO:0034249 negative regulation of cellular amide metabolic process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0010948 negative regulation of cell cycle process; GO:0072413 signal transduction involved in mitotic cell cycle checkpoint; GO:0031047 gene silencing by RNA; GO:1902400 intracellular signal transduction involved in G1 DNA damage checkpoint; GO:0032269 negative regulation of cellular protein metabolic process; GO:0048583 regulation of response to stimulus; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0090305 nucleic acid phosphodiester bond hydrolysis; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0044707 single-multicellular organism process; GO:0007346 regulation of mitotic cell cycle; GO:0017148 negative regulation of translation; GO:0033144 negative regulation of intracellular steroid hormone receptor signaling pathway; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic; GO:1903047 mitotic cell cycle process; GO:0051239 regulation of multicellular organismal process; GO:0030330 DNA damage response, signal transduction by p53 class mediator; GO:0045892 negative regulation of transcription, DNA-templated; GO:0044270 cellular nitrogen compound catabolic process; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1902402 signal transduction involved in mitotic DNA damage checkpoint; GO:1901987 regulation of cell cycle phase transition; GO:0009889 regulation of biosynthetic process; GO:0044819 mitotic G1/S transition checkpoint; GO:0009896 positive regulation of catabolic process; GO:0007093 mitotic cell cycle checkpoint; GO:0044248 cellular catabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0007275 multicellular organism development; GO:0061013 regulation of mRNA catabolic process; GO:0009966 regulation of signal transduction; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0045787 positive regulation of cell cycle; GO:0051254 positive regulation of RNA metabolic process; GO:0006950 response to stress; GO:0072331 signal transduction by p53 class mediator; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0006974 cellular response to DNA damage stimulus; GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway; GO:0034248 regulation of cellular amide metabolic process; GO:1903311 regulation of mRNA metabolic process; GO:0009890 negative regulation of biosynthetic process; GO:0031325 positive regulation of cellular metabolic process; GO:0048387 negative regulation of retinoic acid receptor signaling pathway; GO:0035195 gene silencing by miRNA; GO:0050793 regulation of developmental process; GO:2000045 regulation of G1/S transition of mitotic cell cycle; GO:0048385 regulation of retinoic acid receptor signaling pathway; GO:0009968 negative regulation of signal transduction; GO:0031331 positive regulation of cellular catabolic process; GO:0023051 regulation of signaling; GO:0035194 posttranscriptional gene silencing by RNA; GO:0044783 G1 DNA damage checkpoint; GO:2000036 regulation of stem cell population maintenance; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0051253 negative regulation of RNA metabolic process; GO:1902115 regulation of organelle assembly; GO:0051130 positive regulation of cellular component organization; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0045930 negative regulation of mitotic cell cycle; GO:0000077 DNA damage checkpoint; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0044774 mitotic DNA integrity checkpoint; GO:1901991 negative regulation of mitotic cell cycle phase transition; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:1902806 regulation of cell cycle G1/S phase transition; GO:0000075 cell cycle checkpoint; GO:1901361 organic cyclic compound catabolic process; GO:0051726 regulation of cell cycle; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0031571 mitotic G1 DNA damage checkpoint; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0031570 DNA integrity checkpoint; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:1903313 positive regulation of mRNA metabolic process; GO:0016070 RNA metabolic process; GO:0006401 RNA catabolic process; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0090304 nucleic acid metabolic process; GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; GO:0006351 transcription, DNA-templated; GO:0010638 positive regulation of organelle organization; GO:1902117 positive regulation of organelle assembly; GO:1902679 negative regulation of RNA biosynthetic process; GO:0019222 regulation of metabolic process; GO:0033143 regulation of intracellular steroid hormone receptor signaling pathway; GO:0048856 anatomical structure development; GO:0072401 signal transduction involved in DNA integrity checkpoint; GO:0045786 negative regulation of cell cycle; GO:0072395 signal transduction involved in cell cycle checkpoint; GO:0006725 cellular aromatic compound metabolic process; GO:0010603 regulation of cytoplasmic mRNA processing body assembly; GO:1901988 negative regulation of cell cycle phase transition; GO:1900153 positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044087 regulation of cellular component biogenesis; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening; GO:0061014 positive regulation of mRNA catabolic process; GO:1900151 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; GO:0042770 signal transduction in response to DNA damage; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0071156 regulation of cell cycle arrest; GO:0044265 cellular macromolecule catabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0072422 signal transduction involved in DNA damage checkpoint; GO:0035556 intracellular signal transduction; GO:0010629 negative regulation of gene expression; GO:0016441 posttranscriptional gene silencing; GO:0006807 nitrogen compound metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0033043 regulation of organelle organization; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening; GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly; GO:0048585 negative regulation of response to stimulus; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0040029 regulation of gene expression, epigenetic; GO:0016458 gene silencing; GO:0090501 RNA phosphodiester bond hydrolysis; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0033146 regulation of intracellular estrogen receptor signaling pathway; GO:0006417 regulation of translation; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0009057 macromolecule catabolic process; GO:0071158 positive regulation of cell cycle arrest; GO:0051248 negative regulation of protein metabolic process; GO:0010467 gene expression; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0022402 cell cycle process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0051128 regulation of cellular component organization; GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening; GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0044089 positive regulation of cellular component biogenesis; GO:0065007 biological regulation; GO:0046700 heterocycle catabolic process; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0000932 P-body; GO:0005737 cytoplasm; GO:0044438 microbody part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0005778 peroxisomal membrane; GO:0043228 non-membrane-bounded organelle; GO:0005622 intracellular; GO:0044464 cell part; GO:0042579 microbody; GO:0098805 whole membrane; GO:0030015 CCR4-NOT core complex; GO:0030014 CCR4-NOT complex; GO:0043227 membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0031903 microbody membrane; GO:0044439 peroxisomal part; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005777 peroxisome; GO:0044446 intracellular organelle part; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0035770 ribonucleoprotein granule; GO:1990904 ribonucleoprotein complex; GO:0043234 protein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0044444 cytoplasmic part; ","GO:0030331 estrogen receptor binding; GO:0003723 RNA binding; GO:0070016 armadillo repeat domain binding; GO:0005102 receptor binding; GO:0005515 protein binding; GO:0051427 hormone receptor binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032947 protein complex scaffold; GO:0042974 retinoic acid receptor binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0035258 steroid hormone receptor binding; GO:0035257 nuclear hormone receptor binding; GO:0019904 protein domain specific binding; GO:0005198 structural molecule activity; GO:0008134 transcription factor binding; ","K12604","CNOT1; CCR4-NOT transcription complex subunit 1","hsa03018 RNA degradation - Homo sapiens (human); ","IPR032193; IPR032191; IPR007196; IPR032194; IPR024557; ","\"CCR4-NOT transcription complex subunit 1, TTP binding domain; CCR4-NOT transcription complex subunit 1, CAF1-binding domain; CCR4-Not complex component, Not1, C-terminal; CCR4-NOT transcription complex subunit 1, HEAT repeat; CCR4-Not complex, Not1 subunit, domain of unknown function DUF3819; \"\r"]
["A5YM69","Rho guanine nucleotide exchange factor 35 OS=Homo sapiens OX=9606 GN=ARHGEF35","ARHGEF35",53.286,8.1861,4.8,2,2,2,1.159,1.049,0.943,0.951,0.947,0.969,0.91,0.269,"nucleus\r",{"$nulls":6},"IPR029212; ","\"Rho guanine nucleotide exchange factor 5/35, N-terminal; \"\r"]
["A6NDG6","Glycerol-3-phosphate phosphatase OS=Homo sapiens OX=9606 GN=PGP","PGP",34.006,6.4547,6.5,2,2,2,0.885,0.903,1.051,1.139,1.007,1.016,1.114,0.18,"extracellular\r","GO:0046486 glycerolipid metabolic process; GO:0006066 alcohol metabolic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0008152 metabolic process; GO:0044262 cellular carbohydrate metabolic process; GO:0006650 glycerophospholipid metabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0034637 cellular carbohydrate biosynthetic process; GO:0006629 lipid metabolic process; GO:0010677 negative regulation of cellular carbohydrate metabolic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0019401 alditol biosynthetic process; GO:0010675 regulation of cellular carbohydrate metabolic process; GO:0045721 negative regulation of gluconeogenesis; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901617 organic hydroxy compound biosynthetic process; GO:0005975 carbohydrate metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0050789 regulation of biological process; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006464 cellular protein modification process; GO:0036211 protein modification process; GO:0050794 regulation of cellular process; GO:0043255 regulation of carbohydrate biosynthetic process; GO:0016051 carbohydrate biosynthetic process; GO:0006111 regulation of gluconeogenesis; GO:1901615 organic hydroxy compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0006071 glycerol metabolic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0010906 regulation of glucose metabolic process; GO:0006114 glycerol biosynthetic process; GO:0071704 organic substance metabolic process; GO:0009889 regulation of biosynthetic process; GO:0009987 cellular process; GO:0019400 alditol metabolic process; GO:0035335 peptidyl-tyrosine dephosphorylation; GO:0044711 single-organism biosynthetic process; GO:0046165 alcohol biosynthetic process; GO:0006109 regulation of carbohydrate metabolic process; GO:0044238 primary metabolic process; GO:0006470 protein dephosphorylation; GO:0009892 negative regulation of metabolic process; GO:0016311 dephosphorylation; GO:1901576 organic substance biosynthetic process; GO:0019751 polyol metabolic process; GO:0044249 cellular biosynthetic process; GO:0009890 negative regulation of biosynthetic process; GO:0045912 negative regulation of carbohydrate metabolic process; GO:0006793 phosphorus metabolic process; GO:0044283 small molecule biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0046173 polyol biosynthetic process; GO:0006644 phospholipid metabolic process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0043412 macromolecule modification; GO:0065007 biological regulation; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:0000287 magnesium ion binding; GO:0043136 glycerol-3-phosphatase activity; GO:0016791 phosphatase activity; GO:0043167 ion binding; GO:0000121 glycerol-1-phosphatase activity; GO:0016787 hydrolase activity; GO:0004721 phosphoprotein phosphatase activity; GO:0042578 phosphoric ester hydrolase activity; GO:0003824 catalytic activity; GO:0004725 protein tyrosine phosphatase activity; GO:0005488 binding; GO:0098519 nucleotide phosphatase activity, acting on free nucleotides; GO:0016788 hydrolase activity, acting on ester bonds; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0008967 phosphoglycolate phosphatase activity; ","K19269","PGP; phosphoglycolate phosphatase [EC:3.1.3.18 3.1.3.48]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); hsa00630 Glyoxylate and dicarboxylate metabolism - Homo sapiens (human); ","IPR023215; IPR023214; ","Nitrophenylphosphatase-like  domain; HAD-like domain; \r"]
["A6NDU8","UPF0600 protein C5orf51 OS=Homo sapiens OX=9606 GN=C5orf51","C5orf51",33.62,14.074,4.8,1,1,1,0.805,1.018,1.103,0.982,1.067,1.024,1.05,0.589,"extracellular\r",null,"GO:0043229 intracellular organelle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; "]
["A6NHR9","Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1","SMCHD1",226.37,3.6194,0.5,1,1,1,1.028,0.815,0.883,1.096,1.123,1.052,1.2,0.0576,"cytoplasm\r","GO:0010468 regulation of gene expression; GO:0040029 regulation of gene expression, epigenetic; GO:0016043 cellular component organization; GO:0050789 regulation of biological process; GO:0051276 chromosome organization; GO:0009048 dosage compensation by inactivation of X chromosome; GO:0007549 dosage compensation; GO:0060255 regulation of macromolecule metabolic process; GO:0006996 organelle organization; GO:0019222 regulation of metabolic process; GO:0009987 cellular process; GO:0060821 inactivation of X chromosome by DNA methylation; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0001740 Barr body; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0000805 X chromosome; GO:0044446 intracellular organelle part; GO:0000803 sex chromosome; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0005694 chromosome; GO:0000228 nuclear chromosome; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ",{"$nulls":3},"IPR010935; IPR003594; ","\"SMCs flexible hinge; Histidine kinase-like ATPase, C-terminal domain; \"\r"]
["A6NMZ7","Collagen alpha-6(VI) chain OS=Homo sapiens OX=9606 GN=COL6A6","COL6A6",247.17,170.11,12.4,24,36,22,1.144,1.115,1.17,0.819,0.879,0.873,0.75,0.000402,"endoplasmic reticulum\r","GO:0044707 single-multicellular organism process; GO:0044712 single-organism catabolic process; GO:0044236 multicellular organism metabolic process; GO:0044699 single-organism process; GO:0032501 multicellular organismal process; GO:0071704 organic substance metabolic process; GO:0022610 biological adhesion; GO:0044243 multicellular organismal catabolic process; GO:0008152 metabolic process; GO:0044710 single-organism metabolic process; GO:0032963 collagen metabolic process; GO:0007155 cell adhesion; GO:0043170 macromolecule metabolic process; GO:0009056 catabolic process; GO:0044259 multicellular organismal macromolecule metabolic process; GO:0030574 collagen catabolic process; ","GO:0031012 extracellular matrix; GO:0032991 macromolecular complex; GO:0044421 extracellular region part; GO:0043234 protein complex; GO:0005576 extracellular region; GO:0005581 collagen trimer; GO:0005578 proteinaceous extracellular matrix; ",null,"K06238","COL6A; collagen, type VI, alpha","hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa04512 ECM-receptor interaction - Homo sapiens (human); hsa04974 Protein digestion and absorption - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); ","IPR002035; ","\"von Willebrand factor, type A; \"\r"]
["A8K2U0","Alpha-2-macroglobulin-like protein 1 OS=Homo sapiens OX=9606 GN=A2ML1","A2ML1",161.1,210.5,22.8,31,67,31,0.684,0.702,0.744,1.262,1.281,1.295,1.802,2.11e-05,"extracellular\r","GO:0050794 regulation of cellular process; GO:0052548 regulation of endopeptidase activity; GO:0010951 negative regulation of endopeptidase activity; GO:0045861 negative regulation of proteolysis; GO:0080090 regulation of primary metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0030162 regulation of proteolysis; GO:0031323 regulation of cellular metabolic process; GO:0043086 negative regulation of catalytic activity; GO:0009892 negative regulation of metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051346 negative regulation of hydrolase activity; GO:0010466 negative regulation of peptidase activity; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0051246 regulation of protein metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0052547 regulation of peptidase activity; GO:0065007 biological regulation; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:0004867 serine-type endopeptidase inhibitor activity; GO:0030234 enzyme regulator activity; GO:0030414 peptidase inhibitor activity; GO:0061134 peptidase regulator activity; GO:0061135 endopeptidase regulator activity; GO:0098772 molecular function regulator; GO:0004857 enzyme inhibitor activity; GO:0004866 endopeptidase inhibitor activity; ",{"$nulls":3},"IPR002890; IPR011625; IPR009048; IPR014756; IPR001599; IPR008930; IPR019565; IPR011626; ","\"Alpha-2-macroglobulin, N-terminal; Alpha-2-macroglobulin, N-terminal 2; Alpha-macroglobulin, receptor-binding; Immunoglobulin E-set; Alpha-2-macroglobulin; Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid; Alpha-2-macroglobulin, thiol-ester bond-forming; Alpha-macroglobulin complement component; \"\r"]
["A8TX70","Collagen alpha-5(VI) chain OS=Homo sapiens OX=9606 GN=COL6A5","COL6A5",289.92,21.505,3.6,10,15,8,1.085,1.142,1.116,0.916,0.903,0.891,0.811,0.000239,"endoplasmic reticulum\r","GO:0044707 single-multicellular organism process; GO:0044712 single-organism catabolic process; GO:0044236 multicellular organism metabolic process; GO:0044699 single-organism process; GO:0032501 multicellular organismal process; GO:0071704 organic substance metabolic process; GO:0022610 biological adhesion; GO:0044243 multicellular organismal catabolic process; GO:0008152 metabolic process; GO:0044710 single-organism metabolic process; GO:0032963 collagen metabolic process; GO:0007155 cell adhesion; GO:0043170 macromolecule metabolic process; GO:0009056 catabolic process; GO:0044259 multicellular organismal macromolecule metabolic process; GO:0030574 collagen catabolic process; ","GO:0031012 extracellular matrix; GO:0032991 macromolecular complex; GO:0044421 extracellular region part; GO:0043234 protein complex; GO:0005576 extracellular region; GO:0005581 collagen trimer; GO:0005578 proteinaceous extracellular matrix; ","GO:0005515 protein binding; GO:0005488 binding; ","K06238","COL6A; collagen, type VI, alpha","hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa04512 ECM-receptor interaction - Homo sapiens (human); hsa04974 Protein digestion and absorption - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); ","IPR002035; ","\"von Willebrand factor, type A; \"\r"]
["B0I1T2","Unconventional myosin-Ig OS=Homo sapiens OX=9606 GN=MYO1G","MYO1G",116.44,34.879,8.8,8,9,8,0.884,1.009,0.904,1.077,1.065,1.033,1.135,0.0398,"cyto_nucl\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0016477 cell migration; GO:0072678 T cell migration; GO:0051674 localization of cell; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0007166 cell surface receptor signaling pathway; GO:0002252 immune effector process; GO:0038094 Fc-gamma receptor signaling pathway; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0051234 establishment of localization; GO:0006909 phagocytosis; GO:0022610 biological adhesion; GO:0007165 signal transduction; GO:0007154 cell communication; GO:1902578 single-organism localization; GO:0002250 adaptive immune response; GO:0002757 immune response-activating signal transduction; GO:0007155 cell adhesion; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0038093 Fc receptor signaling pathway; GO:0071976 cell gliding; GO:0002449 lymphocyte mediated immunity; GO:0050778 positive regulation of immune response; GO:0009987 cellular process; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis; GO:0051716 cellular response to stimulus; GO:0002253 activation of immune response; GO:0002443 leukocyte mediated immunity; GO:0002456 T cell mediated immunity; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0002376 immune system process; GO:0048870 cell motility; GO:0023052 signaling; GO:0002764 immune response-regulating signaling pathway; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0072676 lymphocyte migration; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0050900 leukocyte migration; GO:0031589 cell-substrate adhesion; GO:0032940 secretion by cell; GO:0002684 positive regulation of immune system process; GO:0048583 regulation of response to stimulus; GO:0006928 movement of cell or subcellular component; GO:0002682 regulation of immune system process; GO:0002431 Fc receptor mediated stimulatory signaling pathway; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0040011 locomotion; GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0006955 immune response; GO:0006887 exocytosis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0098858 actin-based cell projection; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0031256 leading edge membrane; GO:0005622 intracellular; GO:0044425 membrane part; GO:0044464 cell part; GO:0001891 phagocytic cup; GO:0030027 lamellipodium; GO:1903561 extracellular vesicle; GO:0030175 filopodium; GO:0016459 myosin complex; GO:0043227 membrane-bounded organelle; GO:0031252 cell leading edge; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0005576 extracellular region; GO:0015629 actin cytoskeleton; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0005902 microvillus; GO:0043234 protein complex; GO:0043230 extracellular organelle; ","GO:0003774 motor activity; GO:1901265 nucleoside phosphate binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:1902936 phosphatidylinositol bisphosphate binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0008092 cytoskeletal protein binding; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005546 phosphatidylinositol-4,5-bisphosphate binding; GO:0005488 binding; GO:0035091 phosphatidylinositol binding; GO:0032550 purine ribonucleoside binding; GO:0008289 lipid binding; GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:1901981 phosphatidylinositol phosphate binding; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0005516 calmodulin binding; GO:0043325 phosphatidylinositol-3,4-bisphosphate binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0005543 phospholipid binding; GO:0003779 actin binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; ","K10356",null,null,"IPR010926; IPR027417; IPR001609; ","\"Class I myosin tail homology domain; P-loop containing nucleoside triphosphate hydrolase; Myosin head, motor domain; \"\r"]
["C4AMC7","Putative WAS protein family homolog 3 OS=Homo sapiens OX=9606 GN=WASH3P","WASH3P",49.994,13.835,8.2,3,4,3,1.01,0.969,0.955,1,1.058,1.065,1.064,0.0753,"cyto_nucl\r","GO:0030833 regulation of actin filament polymerization; GO:0010256 endomembrane system organization; GO:0034314 Arp2/3 complex-mediated actin nucleation; GO:0065008 regulation of biological quality; GO:0072594 establishment of protein localization to organelle; GO:0032273 positive regulation of protein polymerization; GO:0044699 single-organism process; GO:0006623 protein targeting to vacuole; GO:0030832 regulation of actin filament length; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0098927 vesicle-mediated transport between endosomal compartments; GO:0006605 protein targeting; GO:0051130 positive regulation of cellular component organization; GO:0030036 actin cytoskeleton organization; GO:0051649 establishment of localization in cell; GO:0072666 establishment of protein localization to vacuole; GO:0032535 regulation of cellular component size; GO:0045010 actin nucleation; GO:0032271 regulation of protein polymerization; GO:0031334 positive regulation of protein complex assembly; GO:0033365 protein localization to organelle; GO:0051493 regulation of cytoskeleton organization; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0061462 protein localization to lysosome; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0072665 protein localization to vacuole; GO:0006810 transport; GO:0016197 endosomal transport; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0043254 regulation of protein complex assembly; GO:0042147 retrograde transport, endosome to Golgi; GO:0010638 positive regulation of organelle organization; GO:1902905 positive regulation of supramolecular fiber organization; GO:0097435 supramolecular fiber organization; GO:1902903 regulation of supramolecular fiber organization; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0032956 regulation of actin cytoskeleton organization; GO:0007015 actin filament organization; GO:0044087 regulation of cellular component biogenesis; GO:0006622 protein targeting to lysosome; GO:0006886 intracellular protein transport; GO:0034613 cellular protein localization; GO:0016482 cytosolic transport; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0045022 early endosome to late endosome transport; GO:0007041 lysosomal transport; GO:0051495 positive regulation of cytoskeleton organization; GO:0016192 vesicle-mediated transport; GO:0016050 vesicle organization; GO:0033043 regulation of organelle organization; GO:0032970 regulation of actin filament-based process; GO:0071702 organic substance transport; GO:0048518 positive regulation of biological process; GO:0030838 positive regulation of actin filament polymerization; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0008064 regulation of actin polymerization or depolymerization; GO:0070727 cellular macromolecule localization; GO:0006996 organelle organization; GO:0007034 vacuolar transport; GO:0030029 actin filament-based process; GO:0090066 regulation of anatomical structure size; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0007032 endosome organization; GO:0044089 positive regulation of cellular component biogenesis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044450 microtubule organizing center part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0055038 recycling endosome membrane; GO:0044424 intracellular part; GO:0098858 actin-based cell projection; GO:0005623 cell; GO:0044422 organelle part; GO:0005776 autophagosome; GO:0005769 early endosome; GO:0055037 recycling endosome; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0005815 microtubule organizing center; GO:0015630 microtubule cytoskeleton; GO:0044464 cell part; GO:0005622 intracellular; GO:0098805 whole membrane; GO:0030027 lamellipodium; GO:0030175 filopodium; GO:0005768 endosome; GO:0031901 early endosome membrane; GO:0043227 membrane-bounded organelle; GO:0031252 cell leading edge; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0010008 endosome membrane; GO:0042995 cell projection; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0071203 WASH complex; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0005829 cytosol; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005813 centrosome; GO:0005773 vacuole; GO:0005814 centriole; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0003779 actin binding; GO:0015631 tubulin binding; GO:0005515 protein binding; GO:0043014 alpha-tubulin binding; GO:0008092 cytoskeletal protein binding; GO:0005488 binding; ","K18461","WASH1; WAS protein family homolog 1","hsa04144 Endocytosis - Homo sapiens (human); ","IPR021854; IPR003124; ","\"WASH1, WAHD domain; WH2 domain; \"\r"]
["L0R6Q1","SLC35A4 upstream open reading frame protein OS=Homo sapiens OX=9606 GN=SLC35A4","SLC35A4",11.133,4.4762,22.3,3,3,3,0.893,1.116,0.975,1.05,1.03,0.948,1.015,0.816,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0032270 positive regulation of cellular protein metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0010608 posttranscriptional regulation of gene expression; GO:0009891 positive regulation of biosynthetic process; GO:0043555 regulation of translation in response to stress; GO:0032056 positive regulation of translation in response to stress; GO:0050896 response to stimulus; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0009987 cellular process; GO:0010468 regulation of gene expression; GO:0051716 cellular response to stimulus; GO:0031326 regulation of cellular biosynthetic process; GO:0006950 response to stress; GO:0080090 regulation of primary metabolic process; GO:0045727 positive regulation of translation; GO:0048522 positive regulation of cellular process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0048518 positive regulation of biological process; GO:0034248 regulation of cellular amide metabolic process; GO:0051247 positive regulation of protein metabolic process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0051246 regulation of protein metabolic process; GO:0006417 regulation of translation; GO:0031325 positive regulation of cellular metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0034250 positive regulation of cellular amide metabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0065007 biological regulation; "]
["O00115","Deoxyribonuclease-2-alpha OS=Homo sapiens OX=9606 GN=DNASE2","DNASE2",39.58,4.9961,5.3,2,2,2,1.008,1.169,1.083,0.9,0.968,0.892,0.847,0.0298,"extracellular\r","GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0065008 regulation of biological quality; GO:0006308 DNA catabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0002262 myeloid cell homeostasis; GO:0006259 DNA metabolic process; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006309 apoptotic DNA fragmentation; GO:0071704 organic substance metabolic process; GO:0034101 erythrocyte homeostasis; GO:0042592 homeostatic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0030154 cell differentiation; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0030262 apoptotic nuclear changes; GO:0006139 nucleobase-containing compound metabolic process; GO:0006915 apoptotic process; GO:0044248 cellular catabolic process; GO:1901361 organic cyclic compound catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0043170 macromolecule metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0009987 cellular process; GO:0032502 developmental process; GO:0044265 cellular macromolecule catabolic process; GO:0030099 myeloid cell differentiation; GO:0048731 system development; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0002376 immune system process; GO:0002520 immune system development; GO:0006921 cellular component disassembly involved in execution phase of apoptosis; GO:0044238 primary metabolic process; GO:0000737 DNA catabolic process, endonucleolytic; GO:0032501 multicellular organismal process; GO:0048534 hematopoietic or lymphoid organ development; GO:0030097 hemopoiesis; GO:0048872 homeostasis of number of cells; GO:0019439 aromatic compound catabolic process; GO:1901575 organic substance catabolic process; GO:0048513 animal organ development; GO:0090304 nucleic acid metabolic process; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0030218 erythrocyte differentiation; GO:0009057 macromolecule catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0022411 cellular component disassembly; GO:0097194 execution phase of apoptosis; GO:0012501 programmed cell death; GO:0090305 nucleic acid phosphodiester bond hydrolysis; GO:0048856 anatomical structure development; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:0046700 heterocycle catabolic process; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0005773 vacuole; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0000323 lytic vacuole; ","GO:0003677 DNA binding; GO:0004536 deoxyribonuclease activity; GO:0004520 endodeoxyribonuclease activity; GO:0016787 hydrolase activity; GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters; GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0004518 nuclease activity; GO:0004531 deoxyribonuclease II activity; GO:0004519 endonuclease activity; ","K01158","DNASE2; deoxyribonuclease II [EC:3.1.22.1]","hsa04142 Lysosome - Homo sapiens (human); "]
["O00116","Alkyldihydroxyacetonephosphate synthase, peroxisomal OS=Homo sapiens OX=9606 GN=AGPS","AGPS",72.911,36.005,8.7,4,4,4,0.982,0.994,0.879,0.99,0.985,1.172,1.102,0.24,"cytoplasm\r","GO:0008611 ether lipid biosynthetic process; GO:0044711 single-organism biosynthetic process; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0046504 glycerol ether biosynthetic process; GO:0044763 single-organism cellular process; GO:0046485 ether lipid metabolic process; GO:0044699 single-organism process; GO:0018904 ether metabolic process; GO:0044255 cellular lipid metabolic process; GO:0009058 biosynthetic process; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0071704 organic substance metabolic process; GO:0008610 lipid biosynthetic process; GO:0008152 metabolic process; GO:0044710 single-organism metabolic process; GO:0006662 glycerol ether metabolic process; GO:0009987 cellular process; GO:1901503 ether biosynthetic process; GO:0006629 lipid metabolic process; GO:0097384 cellular lipid biosynthetic process; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044438 microbody part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005778 peroxisomal membrane; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0005782 peroxisomal matrix; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0042579 microbody; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0031903 microbody membrane; GO:0044439 peroxisomal part; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005777 peroxisome; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0031907 microbody lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0050660 flavin adenine dinucleotide binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0048037 cofactor binding; GO:0016491 oxidoreductase activity; GO:0071949 FAD binding; GO:0016614 oxidoreductase activity, acting on CH-OH group of donors; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0008609 alkylglycerone-phosphate synthase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups; GO:0043168 anion binding; GO:0016740 transferase activity; GO:0050662 coenzyme binding; GO:0036094 small molecule binding; ","K00803","AGPS; alkyldihydroxyacetonephosphate synthase [EC:2.5.1.26]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00565 Ether lipid metabolism - Homo sapiens (human); hsa04146 Peroxisome - Homo sapiens (human); ","IPR016166; IPR004113; IPR016169; IPR016164; IPR016167; IPR006094; ","\"FAD-binding, type 2; FAD-linked oxidase, C-terminal; CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2; FAD-linked oxidase-like, C-terminal; FAD-binding, type 2, subdomain 1; FAD linked oxidase, N-terminal; \"\r"]
["O00142","Thymidine kinase 2, mitochondrial OS=Homo sapiens OX=9606 GN=TK2","TK2",31.004,4.4383,6.8,2,2,2,1.091,1.204,1.223,0.861,0.864,0.788,0.714,1.98E-3,"mitochondria\r","GO:0009116 nucleoside metabolic process; GO:0046125 pyrimidine deoxyribonucleoside metabolic process; GO:0009117 nucleotide metabolic process; GO:0009157 deoxyribonucleoside monophosphate biosynthetic process; GO:0044699 single-organism process; GO:0009163 nucleoside biosynthetic process; GO:0009058 biosynthetic process; GO:0043174 nucleoside salvage; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0009162 deoxyribonucleoside monophosphate metabolic process; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0046134 pyrimidine nucleoside biosynthetic process; GO:0006213 pyrimidine nucleoside metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0072527 pyrimidine-containing compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0018130 heterocycle biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0090407 organophosphate biosynthetic process; GO:0090304 nucleic acid metabolic process; GO:0043094 cellular metabolic compound salvage; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:1901657 glycosyl compound metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0046104 thymidine metabolic process; GO:0016310 phosphorylation; GO:0009165 nucleotide biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0006259 DNA metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0072528 pyrimidine-containing compound biosynthetic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0071897 DNA biosynthetic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0009124 nucleoside monophosphate biosynthetic process; GO:0044711 single-organism biosynthetic process; GO:0043097 pyrimidine nucleoside salvage; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0009120 deoxyribonucleoside metabolic process; GO:0046092 deoxycytidine metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0008655 pyrimidine-containing compound salvage; GO:0034645 cellular macromolecule biosynthetic process; GO:0006793 phosphorus metabolic process; GO:1901659 glycosyl compound biosynthetic process; GO:0019637 organophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0009123 nucleoside monophosphate metabolic process; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0005524 ATP binding; GO:0019206 nucleoside kinase activity; GO:1901265 nucleoside phosphate binding; GO:0004137 deoxycytidine kinase activity; GO:0019205 nucleobase-containing compound kinase activity; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0000166 nucleotide binding; GO:0004797 thymidine kinase activity; GO:0019136 deoxynucleoside kinase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016301 kinase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0016740 transferase activity; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K00857","tdk; thymidine kinase [EC:2.7.1.21]","hsa00983 Drug metabolism - other enzymes - Homo sapiens (human); hsa00240 Pyrimidine metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR027417; IPR031314; ","P-loop containing nucleoside triphosphate hydrolase; Deoxynucleoside kinase domain; \r"]
["O00148","ATP-dependent RNA helicase DDX39A OS=Homo sapiens OX=9606 GN=DDX39A","DDX39A",49.129,21.493,24.4,11,15,5,0.756,0.786,0.762,1.297,1.263,1.12,1.597,5.62E-4,"cytoplasm\r","GO:0050658 RNA transport; GO:0097659 nucleic acid-templated transcription; GO:0009058 biosynthetic process; GO:0051168 nuclear export; GO:0051169 nuclear transport; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006353 DNA-templated transcription, termination; GO:0071427 mRNA-containing ribonucleoprotein complex export from nucleus; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0050657 nucleic acid transport; GO:0015931 nucleobase-containing compound transport; GO:0043170 macromolecule metabolic process; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0006396 RNA processing; GO:0051716 cellular response to stimulus; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0006611 protein export from nucleus; GO:0071166 ribonucleoprotein complex localization; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006913 nucleocytoplasmic transport; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0031123 RNA 3'-end processing; GO:0033554 cellular response to stress; GO:0046907 intracellular transport; GO:0006725 cellular aromatic compound metabolic process; GO:0031124 mRNA 3'-end processing; GO:0060255 regulation of macromolecule metabolic process; GO:0051028 mRNA transport; GO:0050896 response to stimulus; GO:0051236 establishment of RNA localization; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0006886 intracellular protein transport; GO:0034641 cellular nitrogen compound metabolic process; GO:0034613 cellular protein localization; GO:0009059 macromolecule biosynthetic process; GO:0010501 RNA secondary structure unwinding; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0006406 mRNA export from nucleus; GO:0006950 response to stress; GO:0006369 termination of RNA polymerase II transcription; GO:0006403 RNA localization; GO:0006405 RNA export from nucleus; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0006974 cellular response to DNA damage stimulus; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0071426 ribonucleoprotein complex export from nucleus; GO:0006366 transcription from RNA polymerase II promoter; GO:0010467 gene expression; GO:0051179 localization; GO:0071705 nitrogen compound transport; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005681 spliceosomal complex; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0005622 intracellular; GO:0044464 cell part; GO:1990904 ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0030529 intracellular ribonucleoprotein complex; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0008026 ATP-dependent helicase activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0016887 ATPase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0042802 identical protein binding; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0004004 ATP-dependent RNA helicase activity; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003723 RNA binding; GO:0070035 purine NTP-dependent helicase activity; GO:0005524 ATP binding; GO:0004386 helicase activity; GO:0008186 RNA-dependent ATPase activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003724 RNA helicase activity; GO:0042623 ATPase activity, coupled; GO:0003676 nucleic acid binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; ","K13182",null,null,"IPR014014; IPR011545; IPR027417; IPR014001; IPR001650; ","\"RNA helicase, DEAD-box type, Q motif; DEAD/DEAH box helicase domain; P-loop containing nucleoside triphosphate hydrolase; Helicase superfamily 1/2, ATP-binding domain; Helicase, C-terminal; \"\r"]
["O00151","PDZ and LIM domain protein 1 OS=Homo sapiens OX=9606 GN=PDLIM1","PDLIM1",36.071,89.141,47.4,12,17,12,0.903,0.841,0.882,1.072,1.191,1.128,1.291,2.3E-3,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0010468 regulation of gene expression; GO:0006355 regulation of transcription, DNA-templated; GO:0006950 response to stress; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0009628 response to abiotic stimulus; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0098609 cell-cell adhesion; GO:0010556 regulation of macromolecule biosynthetic process; GO:0050896 response to stimulus; GO:0031323 regulation of cellular metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0022610 biological adhesion; GO:2001141 regulation of RNA biosynthetic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0009889 regulation of biosynthetic process; GO:0001666 response to hypoxia; GO:0006979 response to oxidative stress; GO:0070482 response to oxygen levels; GO:0007155 cell adhesion; GO:0019222 regulation of metabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0036293 response to decreased oxygen levels; GO:0065007 biological regulation; GO:2000112 regulation of cellular macromolecule biosynthetic process; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0070161 anchoring junction; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005913 cell-cell adherens junction; GO:0005667 transcription factor complex; GO:0005911 cell-cell junction; GO:0005623 cell; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0005856 cytoskeleton; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:0030055 cell-substrate junction; GO:0043234 protein complex; GO:0005924 cell-substrate adherens junction; ","GO:0043167 ion binding; GO:0005515 protein binding; GO:0008270 zinc ion binding; GO:0003712 transcription cofactor activity; GO:0098632 protein binding involved in cell-cell adhesion; GO:0050839 cell adhesion molecule binding; GO:0098641 cadherin binding involved in cell-cell adhesion; GO:0098631 protein binding involved in cell adhesion; GO:0046914 transition metal ion binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0003713 transcription coactivator activity; GO:0000988 transcription factor activity, protein binding; ",{"$nulls":3},"IPR001781; IPR006643; IPR001478; IPR031847; ","\"Zinc finger, LIM-type; Zasp-like motif; PDZ domain; Domain of unknown function DUF4749; \"\r"]
["O00154","Cytosolic acyl coenzyme A thioester hydrolase OS=Homo sapiens OX=9606 GN=ACOT7","ACOT7",41.796,14.86,19.5,6,7,6,0.829,0.881,0.848,1.101,1.212,1.117,1.341,0.0011,"mitochondria\r","GO:0051188 cofactor biosynthetic process; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0016053 organic acid biosynthetic process; GO:0009117 nucleotide metabolic process; GO:0035337 fatty-acyl-CoA metabolic process; GO:0044699 single-organism process; GO:0009163 nucleoside biosynthetic process; GO:0046129 purine ribonucleoside biosynthetic process; GO:0044255 cellular lipid metabolic process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0035384 thioester biosynthetic process; GO:0044272 sulfur compound biosynthetic process; GO:0008610 lipid biosynthetic process; GO:0046390 ribose phosphate biosynthetic process; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0051187 cofactor catabolic process; GO:0034032 purine nucleoside bisphosphate metabolic process; GO:0036114 medium-chain fatty-acyl-CoA catabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0034033 purine nucleoside bisphosphate biosynthetic process; GO:0032787 monocarboxylic acid metabolic process; GO:0009108 coenzyme biosynthetic process; GO:0006629 lipid metabolic process; GO:0006790 sulfur compound metabolic process; GO:0018130 heterocycle biosynthetic process; GO:0071616 acyl-CoA biosynthetic process; GO:0044281 small molecule metabolic process; GO:0036115 fatty-acyl-CoA catabolic process; GO:0044763 single-organism cellular process; GO:0072521 purine-containing compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0035336 long-chain fatty-acyl-CoA metabolic process; GO:0006732 coenzyme metabolic process; GO:0006633 fatty acid biosynthetic process; GO:0035338 long-chain fatty-acyl-CoA biosynthetic process; GO:0042451 purine nucleoside biosynthetic process; GO:0051186 cofactor metabolic process; GO:0090407 organophosphate biosynthetic process; GO:1901575 organic substance catabolic process; GO:0046394 carboxylic acid biosynthetic process; GO:0072522 purine-containing compound biosynthetic process; GO:0044710 single-organism metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0044273 sulfur compound catabolic process; GO:0006164 purine nucleotide biosynthetic process; GO:0006082 organic acid metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0043436 oxoacid metabolic process; GO:0009165 nucleotide biosynthetic process; GO:0046949 fatty-acyl-CoA biosynthetic process; GO:0042759 long-chain fatty acid biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:1900533 palmitic acid metabolic process; GO:0009259 ribonucleotide metabolic process; GO:0033866 nucleoside bisphosphate biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0036116 long-chain fatty-acyl-CoA catabolic process; GO:0071704 organic substance metabolic process; GO:1900535 palmitic acid biosynthetic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0015937 coenzyme A biosynthetic process; GO:1901135 carbohydrate derivative metabolic process; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034030 ribonucleoside bisphosphate biosynthetic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0051791 medium-chain fatty acid metabolic process; GO:0009119 ribonucleoside metabolic process; GO:0009987 cellular process; GO:0033865 nucleoside bisphosphate metabolic process; GO:0015936 coenzyme A metabolic process; GO:0044711 single-organism biosynthetic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0035383 thioester metabolic process; GO:0033875 ribonucleoside bisphosphate metabolic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0006631 fatty acid metabolic process; GO:0042455 ribonucleoside biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0006163 purine nucleotide metabolic process; GO:0006637 acyl-CoA metabolic process; GO:0044249 cellular biosynthetic process; GO:0036112 medium-chain fatty-acyl-CoA metabolic process; GO:0046128 purine ribonucleoside metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0009152 purine ribonucleotide biosynthetic process; GO:0006793 phosphorus metabolic process; GO:1901659 glycosyl compound biosynthetic process; GO:0001676 long-chain fatty acid metabolic process; GO:0009260 ribonucleotide biosynthetic process; GO:0044283 small molecule biosynthetic process; GO:0019752 carboxylic acid metabolic process; GO:0051792 medium-chain fatty acid biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0009109 coenzyme catabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0009056 catabolic process; GO:0072330 monocarboxylic acid biosynthetic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0052689 carboxylic ester hydrolase activity; GO:0046983 protein dimerization activity; GO:0043167 ion binding; GO:0036042 long-chain fatty acyl-CoA binding; GO:0047617 acyl-CoA hydrolase activity; GO:0005515 protein binding; GO:0016289 CoA hydrolase activity; GO:0016787 hydrolase activity; GO:0016790 thiolester hydrolase activity; GO:0016290 palmitoyl-CoA hydrolase activity; GO:0048037 cofactor binding; GO:1901681 sulfur compound binding; GO:0102991 myristoyl-CoA hydrolase activity; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0000062 fatty-acyl-CoA binding; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0043168 anion binding; GO:0050662 coenzyme binding; ","K17360","ACOT7; acyl-coenzyme A thioesterase 7 [EC:3.1.2.2]","hsa01040 Biosynthesis of unsaturated fatty acids - Homo sapiens (human); hsa00062 Fatty acid elongation - Homo sapiens (human); ","IPR006683; IPR029069; IPR033120; ","Thioesterase domain; HotDog domain; Hotdog acyl-CoA thioesterase (ACOT)-type domain; \r"]
["O00159","Unconventional myosin-Ic OS=Homo sapiens OX=9606 GN=MYO1C","MYO1C",121.68,205.49,28.9,27,45,27,1.076,1.071,1.04,0.943,0.955,0.938,0.89,0.000615,"cytoplasm\r","GO:0044700 single organism signaling; GO:0050658 RNA transport; GO:0065008 regulation of biological quality; GO:0030335 positive regulation of cell migration; GO:0007166 cell surface receptor signaling pathway; GO:1903533 regulation of protein targeting; GO:0030832 regulation of actin filament length; GO:0015031 protein transport; GO:0015931 nucleobase-containing compound transport; GO:0032879 regulation of localization; GO:0032535 regulation of cellular component size; GO:0070848 response to growth factor; GO:0051493 regulation of cytoskeleton organization; GO:0008104 protein localization; GO:0090314 positive regulation of protein targeting to membrane; GO:0044765 single-organism transport; GO:0051716 cellular response to stimulus; GO:0045815 positive regulation of gene expression, epigenetic; GO:2000810 regulation of bicellular tight junction assembly; GO:0072657 protein localization to membrane; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0090287 regulation of cellular response to growth factor stimulus; GO:0051272 positive regulation of cellular component movement; GO:1901888 regulation of cell junction assembly; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0048583 regulation of response to stimulus; GO:0010604 positive regulation of macromolecule metabolic process; GO:0002682 regulation of immune system process; GO:1902905 positive regulation of supramolecular fiber organization; GO:0051223 regulation of protein transport; GO:1902903 regulation of supramolecular fiber organization; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0032956 regulation of actin cytoskeleton organization; GO:0051028 mRNA transport; GO:2000147 positive regulation of cell motility; GO:1905477 positive regulation of protein localization to membrane; GO:0051236 establishment of RNA localization; GO:0038084 vascular endothelial growth factor signaling pathway; GO:0060341 regulation of cellular localization; GO:1902578 single-organism localization; GO:2000145 regulation of cell motility; GO:0010628 positive regulation of gene expression; GO:0032880 regulation of protein localization; GO:0038093 Fc receptor signaling pathway; GO:0034613 cellular protein localization; GO:0050778 positive regulation of immune response; GO:0009966 regulation of signal transduction; GO:0090150 establishment of protein localization to membrane; GO:0002253 activation of immune response; GO:0051495 positive regulation of cytoskeleton organization; GO:0051270 regulation of cellular component movement; GO:0006403 RNA localization; GO:0016192 vesicle-mediated transport; GO:0038089 positive regulation of cell migration by vascular endothelial growth factor signaling pathway; GO:0002376 immune system process; GO:0032970 regulation of actin filament-based process; GO:0071702 organic substance transport; GO:0030334 regulation of cell migration; GO:0010033 response to organic substance; GO:0030838 positive regulation of actin filament polymerization; GO:0045184 establishment of protein localization; GO:0008064 regulation of actin polymerization or depolymerization; GO:1902547 regulation of cellular response to vascular endothelial growth factor stimulus; GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway; GO:1904951 positive regulation of establishment of protein localization; GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0090313 regulation of protein targeting to membrane; GO:1903827 regulation of cellular protein localization; GO:0030833 regulation of actin filament polymerization; GO:0032273 positive regulation of protein polymerization; GO:0040017 positive regulation of locomotion; GO:0038094 Fc-gamma receptor signaling pathway; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0071363 cellular response to growth factor stimulus; GO:0006909 phagocytosis; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0051130 positive regulation of cellular component organization; GO:0006612 protein targeting to membrane; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0050657 nucleic acid transport; GO:0009893 positive regulation of metabolic process; GO:0032271 regulation of protein polymerization; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0031334 positive regulation of protein complex assembly; GO:0033036 macromolecule localization; GO:0070887 cellular response to chemical stimulus; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis; GO:0010468 regulation of gene expression; GO:0048522 positive regulation of cellular process; GO:0032386 regulation of intracellular transport; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:1900746 regulation of vascular endothelial growth factor signaling pathway; GO:0051050 positive regulation of transport; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0043254 regulation of protein complex assembly; GO:0010638 positive regulation of organelle organization; GO:0019222 regulation of metabolic process; GO:0002431 Fc receptor mediated stimulatory signaling pathway; GO:0051222 positive regulation of protein transport; GO:0016043 cellular component organization; GO:0090316 positive regulation of intracellular protein transport; GO:0002252 immune effector process; GO:1903829 positive regulation of cellular protein localization; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0044087 regulation of cellular component biogenesis; GO:1900076 regulation of cellular response to insulin stimulus; GO:0050896 response to stimulus; GO:0070201 regulation of establishment of protein localization; GO:1905475 regulation of protein localization to membrane; GO:0023056 positive regulation of signaling; GO:0006886 intracellular protein transport; GO:0002757 immune response-activating signal transduction; GO:0010647 positive regulation of cell communication; GO:0033157 regulation of intracellular protein transport; GO:0009987 cellular process; GO:0035924 cellular response to vascular endothelial growth factor stimulus; GO:0051049 regulation of transport; GO:0032388 positive regulation of intracellular transport; GO:0033043 regulation of organelle organization; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:1900078 positive regulation of cellular response to insulin stimulus; GO:0040029 regulation of gene expression, epigenetic; GO:0070727 cellular macromolecule localization; GO:0002684 positive regulation of immune system process; GO:0090066 regulation of anatomical structure size; GO:0051128 regulation of cellular component organization; GO:0009967 positive regulation of signal transduction; GO:0040012 regulation of locomotion; GO:0071705 nitrogen compound transport; GO:0044089 positive regulation of cellular component biogenesis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0098862 cluster of actin-based cell projections; GO:0098857 membrane microdomain; GO:0032587 ruffle membrane; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0098858 actin-based cell projection; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0098590 plasma membrane region; GO:0031256 leading edge membrane; GO:0005622 intracellular; GO:0098589 membrane region; GO:0016459 myosin complex; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0031941 filamentous actin; GO:0031252 cell leading edge; GO:0005643 nuclear pore; GO:0099513 polymeric cytoskeletal fiber; GO:0042995 cell projection; GO:0044430 cytoskeletal part; GO:0031967 organelle envelope; GO:0031981 nuclear lumen; GO:0032421 stereocilium bundle; GO:0005730 nucleolus; GO:0032420 stereocilium; GO:0005576 extracellular region; GO:0016328 lateral plasma membrane; GO:0045160 myosin I complex; GO:0016461 unconventional myosin complex; GO:0099081 supramolecular polymer; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0031975 envelope; GO:0005902 microvillus; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0016323 basolateral plasma membrane; GO:0005903 brush border; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0099512 supramolecular fiber; GO:0016604 nuclear body; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0005884 actin filament; GO:0045121 membrane raft; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0005635 nuclear envelope; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0015629 actin cytoskeleton; GO:0043226 organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0060171 stereocilium membrane; GO:0009925 basal plasma membrane; GO:0001726 ruffle; GO:0031253 cell projection membrane; GO:0044444 cytoplasmic part; GO:0045178 basal part of cell; GO:0044428 nuclear part; ","GO:0051015 actin filament binding; GO:1901265 nucleoside phosphate binding; GO:0003774 motor activity; GO:0005102 receptor binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0017160 Ral GTPase binding; GO:0016887 ATPase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0008092 cytoskeletal protein binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0017016 Ras GTPase binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0008022 protein C-terminus binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0000146 microfilament motor activity; GO:0051020 GTPase binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0030898 actin-dependent ATPase activity; GO:0031267 small GTPase binding; GO:0005524 ATP binding; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0005516 calmodulin binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0042623 ATPase activity, coupled; GO:0003779 actin binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019899 enzyme binding; GO:0036094 small molecule binding; GO:0032403 protein complex binding; ","K10356",null,null,"IPR010926; IPR027417; IPR001609; ","\"Class I myosin tail homology domain; P-loop containing nucleoside triphosphate hydrolase; Myosin head, motor domain; \"\r"]
["O00161","Synaptosomal-associated protein 23 OS=Homo sapiens OX=9606 GN=SNAP23","SNAP23",23.354,61.24,41.7,6,9,6,1.003,1.026,0.984,1.023,0.989,0.964,0.988,0.584,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0002279 mast cell activation involved in immune response; GO:0009914 hormone transport; GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0007269 neurotransmitter secretion; GO:0015031 protein transport; GO:0099003 vesicle-mediated transport in synapse; GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane; GO:0002532 production of molecular mediator involved in inflammatory response; GO:0065003 macromolecular complex assembly; GO:0044801 single-organism membrane fusion; GO:0008104 protein localization; GO:0099500 vesicle fusion to plasma membrane; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0048489 synaptic vesicle transport; GO:0002443 leukocyte mediated immunity; GO:0015696 ammonium transport; GO:0044763 single-organism cellular process; GO:0061025 membrane fusion; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0007267 cell-cell signaling; GO:0016082 synaptic vesicle priming; GO:0010817 regulation of hormone levels; GO:0006906 vesicle fusion; GO:0002441 histamine secretion involved in inflammatory response; GO:0045026 plasma membrane fusion; GO:0099643 signal release from synapse; GO:0051640 organelle localization; GO:0044707 single-multicellular organism process; GO:0046907 intracellular transport; GO:0090174 organelle membrane fusion; GO:0002283 neutrophil activation involved in immune response; GO:0051608 histamine transport; GO:0043303 mast cell degranulation; GO:0045117 azole transport; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:1902580 single-organism cellular localization; GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; GO:0006461 protein complex assembly; GO:0006950 response to stress; GO:0016192 vesicle-mediated transport; GO:0016079 synaptic vesicle exocytosis; GO:0048284 organelle fusion; GO:0023061 signal release; GO:0002376 immune system process; GO:0071702 organic substance transport; GO:0051656 establishment of organelle localization; GO:0002263 cell activation involved in immune response; GO:0097480 establishment of synaptic vesicle localization; GO:0045184 establishment of protein localization; GO:0045055 regulated exocytosis; GO:0099536 synaptic signaling; GO:0006811 ion transport; GO:0006996 organelle organization; GO:0097479 synaptic vesicle localization; GO:0061024 membrane organization; GO:0001775 cell activation; GO:0006892 post-Golgi vesicle-mediated transport; GO:0007268 chemical synaptic transmission; GO:0051179 localization; GO:0006955 immune response; GO:0006887 exocytosis; GO:0001505 regulation of neurotransmitter levels; GO:0002349 histamine production involved in inflammatory response; GO:0044699 single-organism process; GO:0045576 mast cell activation; GO:0099504 synaptic vesicle cycle; GO:0051234 establishment of localization; GO:0046879 hormone secretion; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I; GO:0098916 anterograde trans-synaptic signaling; GO:0033036 macromolecule localization; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0002274 myeloid leukocyte activation; GO:0051650 establishment of vesicle localization; GO:0071822 protein complex subunit organization; GO:0002446 neutrophil mediated immunity; GO:0048002 antigen processing and presentation of peptide antigen; GO:0023052 signaling; GO:0002444 myeloid leukocyte mediated immunity; GO:1902582 single-organism intracellular transport; GO:1902589 single-organism organelle organization; GO:0002553 histamine secretion by mast cell; GO:0032940 secretion by cell; GO:0006954 inflammatory response; GO:0043299 leukocyte degranulation; GO:0006952 defense response; GO:0070271 protein complex biogenesis; GO:0016043 cellular component organization; GO:0002252 immune effector process; GO:0048193 Golgi vesicle transport; GO:0099531 presynaptic process involved in chemical synaptic transmission; GO:0006903 vesicle targeting; GO:0050896 response to stimulus; GO:0006812 cation transport; GO:0051648 vesicle localization; GO:0002448 mast cell mediated immunity; GO:0099537 trans-synaptic signaling; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0032418 lysosome localization; GO:0043623 cellular protein complex assembly; GO:0034622 cellular macromolecular complex assembly; GO:0017156 calcium ion regulated exocytosis; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:0016050 vesicle organization; GO:0044802 single-organism membrane organization; GO:0043312 neutrophil degranulation; GO:0051641 cellular localization; GO:0043933 macromolecular complex subunit organization; GO:0002366 leukocyte activation involved in immune response; GO:0019882 antigen processing and presentation; GO:0042119 neutrophil activation; GO:0001821 histamine secretion; GO:0006836 neurotransmitter transport; GO:0071705 nitrogen compound transport; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0005913 cell-cell adherens junction; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:0043005 neuron projection; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0031201 SNARE complex; GO:0097458 neuron part; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0042995 cell projection; GO:0030666 endocytic vesicle membrane; GO:0070161 anchoring junction; GO:0031981 nuclear lumen; GO:0012506 vesicle membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0042582 azurophil granule; GO:0043231 intracellular membrane-bounded organelle; GO:0030667 secretory granule membrane; GO:0005766 primary lysosome; GO:0005773 vacuole; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0031410 cytoplasmic vesicle; GO:0098796 membrane protein complex; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005911 cell-cell junction; GO:0070821 tertiary granule membrane; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0044464 cell part; GO:0098793 presynapse; GO:0098805 whole membrane; GO:0030670 phagocytic vesicle membrane; GO:0042629 mast cell granule; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0030139 endocytic vesicle; GO:0035579 specific granule membrane; GO:0044456 synapse part; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0070820 tertiary granule; GO:0012505 endomembrane system; GO:0045335 phagocytic vesicle; GO:0045202 synapse; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0005634 nucleus; GO:0042581 specific granule; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0000149 SNARE binding; GO:0005484 SNAP receptor activity; GO:0005515 protein binding; GO:0019905 syntaxin binding; GO:0005488 binding; ","K08508","SNAP23; synaptosomal-associated protein 23","hsa04611 Platelet activation - Homo sapiens (human); hsa04130 SNARE interactions in vesicular transport - Homo sapiens (human); ","IPR000928; IPR000727; ","SNAP-25; Target SNARE coiled-coil homology domain; \r"]
["O00170","AH receptor-interacting protein OS=Homo sapiens OX=9606 GN=AIP","AIP",37.636,34.977,31.8,9,11,9,1.02,0.963,1.037,1.049,0.981,0.95,0.987,0.729,"cytoplasm\r","GO:0044700 single organism signaling; GO:0072594 establishment of protein localization to organelle; GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity; GO:0006839 mitochondrial transport; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006457 protein folding; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0007005 mitochondrion organization; GO:0033365 protein localization to organelle; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0070887 cellular response to chemical stimulus; GO:0051716 cellular response to stimulus; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0043086 negative regulation of catalytic activity; GO:0023052 signaling; GO:0031323 regulation of cellular metabolic process; GO:0006810 transport; GO:1903506 regulation of nucleic acid-templated transcription; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0072655 establishment of protein localization to mitochondrion; GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity; GO:0050794 regulation of cellular process; GO:0071466 cellular response to xenobiotic stimulus; GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0050896 response to stimulus; GO:0051346 negative regulation of hydrolase activity; GO:0071704 organic substance metabolic process; GO:0009410 response to xenobiotic stimulus; GO:0006805 xenobiotic metabolic process; GO:0009889 regulation of biosynthetic process; GO:0006886 intracellular protein transport; GO:0051171 regulation of nitrogen compound metabolic process; GO:0006626 protein targeting to mitochondrion; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0009966 regulation of signal transduction; GO:1902531 regulation of intracellular signal transduction; GO:0022417 protein maturation by protein folding; GO:0010556 regulation of macromolecule biosynthetic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0070585 protein localization to mitochondrion; GO:0051252 regulation of RNA metabolic process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0010738 regulation of protein kinase A signaling; GO:0070727 cellular macromolecule localization; GO:0006996 organelle organization; GO:0010467 gene expression; GO:0051179 localization; GO:0051604 protein maturation; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0043235 receptor complex; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0034751 aryl hydrocarbon receptor complex; GO:0044428 nuclear part; ","GO:0005102 receptor binding; GO:0017162 aryl hydrocarbon receptor binding; GO:0005488 binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0003713 transcription coactivator activity; GO:0019904 protein domain specific binding; GO:0005515 protein binding; GO:0051082 unfolded protein binding; GO:0003712 transcription cofactor activity; GO:0004871 signal transducer activity; GO:0000988 transcription factor activity, protein binding; GO:0036004 GAF domain binding; GO:0008134 transcription factor binding; ","K17767","AIP; AH receptor-interacting protein","hsa04934 Cushing's syndrome - Homo sapiens (human); ","IPR011990; IPR013026; IPR001179; ","Tetratricopeptide-like helical domain; Tetratricopeptide repeat-containing domain; FKBP-type peptidyl-prolyl cis-trans isomerase domain; \r"]
["O00182","Galectin-9 OS=Homo sapiens OX=9606 GN=LGALS9","LGALS9",39.518,5.4418,3.7,1,1,1,0.854,0.897,0.87,1.166,1.189,1.017,1.287,0.00816,"nucleus\r",{"$cut":{"chars":23298,"head":"GO:0044700 single organism signaling; GO:0050672 negative regulation of lymphocyte proliferation; GO:0002694 regulation of leukocyte activation; GO:0010941 regulation of cell death; GO:0032680 regulation of tumor necrosis factor production; GO:0022414 reproductive process; GO:0032656 regulation of interleukin-13 production; GO:0002698 negative regulation of immune effector process; GO:1903306 negative regulation of regulated secretory pathway; GO:0070555 response to interleukin-1; GO:0031347 regulation of defense response; GO:2000665 regulation of interleukin-13 secretion; GO:0044237 cellular metabolic process; GO:0009607 response to biotic stimulus; GO:0032732 positive regulation of interleukin-1 production; GO:0008152 metabolic process; GO:0032673 regulation of interleukin-4 production; GO:0070664 negative regulation of leukocyte proliferation; GO:0032946 positive regulation of mononuclear cell proliferation; GO:0002519 natural killer cell tolerance induction; GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling; GO:0070239 regulation of activated T cell autonomous cell death; GO:0044093 positive regulation of molecular function; GO:1904469 positive regulation of tumor necrosis factor secretion; GO:0044706 multi-multicellular organism process; GO:2000515 negative regulation of CD4-positive, alpha-beta T cell activation; GO:0043370 regulation of CD4-positive, alpha-beta T cell differentiation; GO:0045621 positive regulation of lymphocyte differentiation; GO:0052548 regulation of endopeptidase activity; GO:0051051 negative regulation of transport; GO:0042325 regulation of phosphorylation; GO:0046636 negative regulation of alpha-beta T cell activation; GO:0051716 cellular response to stimulus; GO:0010950 positive regulation of endopeptidase activity; GO:0080090 regulation of primary metabolic process; GO:1903038 negative regulation of leukocyte cell-cell adhesion; GO:1903531 negative regulation of secretion by cell; GO:0044763 single-organism cellular process; GO:0046006 regulation of activated T cell proliferation; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0002520 immune system development; GO:0006935 chemotaxis; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0000165 MAPK cascade; GO:0051092 positive regulation of NF-kappaB transcription factor activity; GO:0032832 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0051223 regulation of protein transport; GO:0032736 positive regulation of interleukin-13 production; GO:0048609 multicellular organismal reproductive process; GO:0002687 positive regulation of leukocyte migration; GO:0042307 positive regulation of protein import into nucleus; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0045589 regulation of regulatory T cell differentiation; GO:0000003 reproduction; GO:0032677 regulation of interleukin-8 production; GO:0044707 single-multicellular organism process; GO:0016310 phosphorylation; GO:0060135 maternal process involved in female pregnancy; GO:2001056 positive regulation of cysteine-type endopeptidase activity; GO:0045580 regulation of T cell differentiation; GO:0001819 positive regulation of cytokine production; GO:0070230 positive regulation of lymphocyte apoptotic process; GO:1901700 response to oxygen-containing compound; GO:0022408 negative regulation of cell-cell adhesion; GO:0017157 regulation of exocytosis; GO:0002715 regulation of natural killer cell mediated immunity; GO:0048519 negative regulation of biological process; GO:0042990 regulation of transcription factor import into nucleus; GO:1903706 regulation of hemopoiesis; GO:2000778 positive regulation of interleukin-6 secretion; GO:0070234 positive regulation of T cell apoptotic process; GO:0050867 positive regulation of cell activation; GO:005"}},"GO:0043229 intracellular organelle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005534 galactose binding; GO:0005488 binding; GO:0070492 oligosaccharide binding; GO:0030246 carbohydrate binding; GO:0005515 protein binding; GO:0048030 disaccharide binding; GO:0048029 monosaccharide binding; GO:0004871 signal transducer activity; GO:0019899 enzyme binding; GO:0036094 small molecule binding; ","K10093",null,null,"IPR001079; IPR013320; ","\"Galectin, carbohydrate recognition domain; Concanavalin A-like lectin/glucanase domain; \"\r"]
["O00186","Syntaxin-binding protein 3 OS=Homo sapiens OX=9606 GN=STXBP3","STXBP3",67.764,44.789,22.1,13,14,13,0.942,0.984,1.027,0.986,1.026,1.034,1.031,0.339,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0060627 regulation of vesicle-mediated transport; GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0009914 hormone transport; GO:0045321 leukocyte activation; GO:0007420 brain development; GO:1903306 negative regulation of regulated secretory pathway; GO:0044699 single-organism process; GO:0051046 regulation of secretion; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0009611 response to wounding; GO:0046879 hormone secretion; GO:0022610 biological adhesion; GO:0016337 single organismal cell-cell adhesion; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0032879 regulation of localization; GO:0007155 cell adhesion; GO:0015758 glucose transport; GO:0009719 response to endogenous stimulus; GO:0009306 protein secretion; GO:0060322 head development; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0042886 amide transport; GO:1901652 response to peptide; GO:0002274 myeloid leukocyte activation; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0051051 negative regulation of transport; GO:0002443 leukocyte mediated immunity; GO:0071822 protein complex subunit organization; GO:0006904 vesicle docking involved in exocytosis; GO:0030168 platelet activation; GO:0002446 neutrophil mediated immunity; GO:0002790 peptide secretion; GO:0098609 cell-cell adhesion; GO:1903531 negative regulation of secretion by cell; GO:0044763 single-organism cellular process; GO:0023052 signaling; GO:1903530 regulation of secretion by cell; GO:0032501 multicellular organismal process; GO:0002444 myeloid leukocyte mediated immunity; GO:0051291 protein heterooligomerization; GO:0006810 transport; GO:0030072 peptide hormone secretion; GO:0010243 response to organonitrogen compound; GO:0048513 animal organ development; GO:0051048 negative regulation of secretion; GO:0032868 response to insulin; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0043434 response to peptide hormone; GO:0007267 cell-cell signaling; GO:0008645 hexose transport; GO:0007417 central nervous system development; GO:0032940 secretion by cell; GO:0098602 single organism cell adhesion; GO:1901698 response to nitrogen compound; GO:0010817 regulation of hormone levels; GO:0050817 coagulation; GO:0043299 leukocyte degranulation; GO:0070271 protein complex biogenesis; GO:0048856 anatomical structure development; GO:0015833 peptide transport; GO:0070527 platelet aggregation; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0045920 negative regulation of exocytosis; GO:0044707 single-multicellular organism process; GO:0002283 neutrophil activation involved in immune response; GO:0015749 monosaccharide transport; GO:0002252 immune effector process; GO:0030073 insulin secretion; GO:1901700 response to oxygen-containing compound; GO:0017157 regulation of exocytosis; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0034109 homotypic cell-cell adhesion; GO:0022406 membrane docking; GO:0007599 hemostasis; GO:0051259 protein oligomerization; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0008643 carbohydrate transport; GO:0036230 granulocyte activation; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0045955 negative regulation of calcium ion-dependent exocytosis; GO:0050878 regulation of body fluid levels; GO:0006950 response to stress; GO:0051049 regulation of transport; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0022615 protein to membrane docking; GO:0002376 immune system process; GO:0023061 signal release; GO:0071702 organic substance transport; GO:0010033 response to organic substance; GO:0043312 neutrophil degranulation; GO:0048278 vesicle docking; GO:1903305 regulation of regulated secretory pathway; GO:0002263 cell activation involved in immune response; GO:0043933 macromolecular complex subunit organization; GO:0002366 leukocyte activation involved in immune response; GO:0045184 establishment of protein localization; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:0042060 wound healing; GO:0044767 single-organism developmental process; GO:0001775 cell activation; GO:0009725 response to hormone; GO:0006955 immune response; GO:0051179 localization; GO:0017158 regulation of calcium ion-dependent exocytosis; GO:0071705 nitrogen compound transport; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:0006887 exocytosis; ","GO:0016323 basolateral plasma membrane; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0016324 apical plasma membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0070062 extracellular exosome; GO:0098590 plasma membrane region; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0045177 apical part of cell; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0070820 tertiary granule; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0042581 specific granule; GO:0031091 platelet alpha granule; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0017075 syntaxin-1 binding; GO:0000149 SNARE binding; GO:0005515 protein binding; GO:0019905 syntaxin binding; GO:0005488 binding; ","K15301",null,null,"IPR027482; ","\"Sec1-like, domain 2; \"\r"]
["O00193","Small acidic protein OS=Homo sapiens OX=9606 GN=SMAP","SMAP",20.332,21.22,16.9,3,7,3,0.775,0.862,0.751,1.244,1.112,1.196,1.487,0.0017,"nucleus\r",{"$nulls":6},"IPR028124; ","Small acidic protein-like domain; \r"]
["O00194","Ras-related protein Rab-27B OS=Homo sapiens OX=9606 GN=RAB27B","RAB27B",24.608,10.583,17,4,6,4,1.025,1.025,1.015,1.035,0.932,0.967,0.957,0.285,"cytoplasm\r","GO:0051640 organelle localization; GO:0044700 single organism signaling; GO:0050794 regulation of cellular process; GO:0060627 regulation of vesicle-mediated transport; GO:0046907 intracellular transport; GO:0002576 platelet degranulation; GO:0044699 single-organism process; GO:0051046 regulation of secretion; GO:0017157 regulation of exocytosis; GO:0050896 response to stimulus; GO:0051234 establishment of localization; GO:0051875 pigment granule localization; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:1902578 single-organism localization; GO:0051905 establishment of pigment granule localization; GO:0071985 multivesicular body sorting pathway; GO:0032879 regulation of localization; GO:0032400 melanosome localization; GO:0051648 vesicle localization; GO:0032402 melanosome transport; GO:1902580 single-organism cellular localization; GO:0051904 pigment granule transport; GO:0009987 cellular process; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0051650 establishment of vesicle localization; GO:0051716 cellular response to stimulus; GO:0035556 intracellular signal transduction; GO:0045921 positive regulation of exocytosis; GO:0051049 regulation of transport; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0007264 small GTPase mediated signal transduction; GO:0051656 establishment of organelle localization; GO:0023052 signaling; GO:1903530 regulation of secretion by cell; GO:0048518 positive regulation of biological process; GO:1902582 single-organism intracellular transport; GO:0051641 cellular localization; GO:0051050 positive regulation of transport; GO:0006810 transport; GO:0045055 regulated exocytosis; GO:0050789 regulation of biological process; GO:1903532 positive regulation of secretion by cell; GO:0032940 secretion by cell; GO:0032401 establishment of melanosome localization; GO:0043473 pigmentation; GO:0051179 localization; GO:0033059 cellular pigmentation; GO:0051047 positive regulation of secretion; GO:0065007 biological regulation; GO:0006887 exocytosis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0042827 platelet dense granule; GO:0016324 apical plasma membrane; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0042588 zymogen granule; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0031088 platelet dense granule membrane; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0048770 pigment granule; GO:0070062 extracellular exosome; GO:0030140 trans-Golgi network transport vesicle; GO:0098590 plasma membrane region; GO:0030136 clathrin-coated vesicle; GO:0031902 late endosome membrane; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0098805 whole membrane; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0098791 Golgi subcompartment; GO:0044431 Golgi apparatus part; GO:0042589 zymogen granule membrane; GO:0005768 endosome; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0005771 multivesicular body; GO:0045177 apical part of cell; GO:0010008 endosome membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0005770 late endosome; GO:0098588 bounding membrane of organelle; GO:0042470 melanosome; GO:0044446 intracellular organelle part; GO:0044440 endosomal part; GO:0005795 Golgi stack; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0005798 Golgi-associated vesicle; GO:0030135 coated vesicle; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0030667 secretory granule membrane; GO:0044459 plasma membrane part; GO:0032585 multivesicular body membrane; GO:0030133 transport vesicle; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0031984 organelle subcompartment; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0031489 myosin V binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0008092 cytoskeletal protein binding; GO:0019003 GDP binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0003924 GTPase activity; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0017076 purine nucleotide binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032555 purine ribonucleotide binding; GO:0019904 protein domain specific binding; GO:0001883 purine nucleoside binding; GO:0032561 guanyl ribonucleotide binding; GO:0017022 myosin binding; GO:0036094 small molecule binding; ","K07886","RAB27B; Ras-related protein Rab-27B","hsa04972 Pancreatic secretion - Homo sapiens (human); ","IPR005225; IPR027417; ","Small GTP-binding protein domain; P-loop containing nucleoside triphosphate hydrolase; \r"]
["O00203","AP-3 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP3B1","AP3B1",121.32,40.222,10.8,10,12,10,0.988,1.047,0.978,0.988,1.054,1.032,1.02,0.519,"cytoplasm\r","GO:0050863 regulation of T cell activation; GO:0002694 regulation of leukocyte activation; GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0072594 establishment of protein localization to organelle; GO:0044699 single-organism process; GO:0006623 protein targeting to vacuole; GO:0051249 regulation of lymphocyte activation; GO:0046635 positive regulation of alpha-beta T cell activation; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0009611 response to wounding; GO:0099003 vesicle-mediated transport in synapse; GO:1902107 positive regulation of leukocyte differentiation; GO:0010970 transport along microtubule; GO:0051649 establishment of localization in cell; GO:0051240 positive regulation of multicellular organismal process; GO:0072666 establishment of protein localization to vacuole; GO:0099517 synaptic vesicle transport along microtubule; GO:0033365 protein localization to organelle; GO:0045621 positive regulation of lymphocyte differentiation; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0008089 anterograde axonal transport; GO:0032438 melanosome organization; GO:0044765 single-organism transport; GO:0051650 establishment of vesicle localization; GO:0061462 protein localization to lysosome; GO:0048489 synaptic vesicle transport; GO:0048007 antigen processing and presentation, exogenous lipid antigen via MHC class Ib; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0051251 positive regulation of lymphocyte activation; GO:0032501 multicellular organismal process; GO:1902582 single-organism intracellular transport; GO:0072665 protein localization to vacuole; GO:0006810 transport; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0099518 vesicle cytoskeletal trafficking; GO:0008088 axo-dendritic transport; GO:0050789 regulation of biological process; GO:0050865 regulation of cell activation; GO:1902105 regulation of leukocyte differentiation; GO:0046634 regulation of alpha-beta T cell activation; GO:0002682 regulation of immune system process; GO:0050817 coagulation; GO:0051094 positive regulation of developmental process; GO:2000026 regulation of multicellular organismal development; GO:0050794 regulation of cellular process; GO:0051640 organelle localization; GO:0072384 organelle transport along microtubule; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0046907 intracellular transport; GO:0099514 synaptic vesicle cytoskeletal transport; GO:0045580 regulation of T cell differentiation; GO:0048490 anterograde synaptic vesicle transport; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:0045597 positive regulation of cell differentiation; GO:0007599 hemostasis; GO:0099111 microtubule-based transport; GO:0030705 cytoskeleton-dependent intracellular transport; GO:1903706 regulation of hemopoiesis; GO:0051136 regulation of NK T cell differentiation; GO:0006622 protein targeting to lysosome; GO:0050867 positive regulation of cell activation; GO:1902578 single-organism localization; GO:0002475 antigen processing and presentation via MHC class Ib; GO:0051648 vesicle localization; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:0006886 intracellular protein transport; GO:1902580 single-organism cellular localization; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0007041 lysosomal transport; GO:1903708 positive regulation of hemopoiesis; GO:0048753 pigment granule organization; GO:0050878 regulation of body fluid levels; GO:0045785 positive regulation of cell adhesion; GO:0006950 response to stress; GO:0022409 positive regulation of cell-cell adhesion; GO:0046637 regulation of alpha-beta T cell differentiation; GO:0016192 vesicle-mediated transport; GO:0098930 axonal transport; GO:0016050 vesicle organization; GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib; GO:0002376 immune system process; GO:0071702 organic substance transport; GO:0045582 positive regulation of T cell differentiation; GO:0051656 establishment of organelle localization; GO:0048518 positive regulation of biological process; GO:1903039 positive regulation of leukocyte cell-cell adhesion; GO:0007017 microtubule-based process; GO:0022407 regulation of cell-cell adhesion; GO:0030155 regulation of cell adhesion; GO:0045619 regulation of lymphocyte differentiation; GO:0097480 establishment of synaptic vesicle localization; GO:0051641 cellular localization; GO:0047496 vesicle transport along microtubule; GO:0045184 establishment of protein localization; GO:0002696 positive regulation of leukocyte activation; GO:0019882 antigen processing and presentation; GO:0007018 microtubule-based movement; GO:0070727 cellular macromolecule localization; GO:0042060 wound healing; GO:0006996 organelle organization; GO:0046638 positive regulation of alpha-beta T cell differentiation; GO:0050870 positive regulation of T cell activation; GO:0007034 vacuolar transport; GO:0097479 synaptic vesicle localization; GO:0002684 positive regulation of immune system process; GO:0043473 pigmentation; GO:0006928 movement of cell or subcellular component; GO:0051138 positive regulation of NK T cell differentiation; GO:0051179 localization; GO:0033059 cellular pigmentation; GO:0050793 regulation of developmental process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0030119 AP-type membrane coat adaptor complex; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0098796 membrane protein complex; GO:0099568 cytoplasmic region; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0032838 cell projection cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0030123 AP-3 adaptor complex; GO:0044422 organelle part; GO:0030662 coated vesicle membrane; GO:0005765 lysosomal membrane; GO:0030136 clathrin-coated vesicle; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005764 lysosome; GO:0098805 whole membrane; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0042995 cell projection; GO:0098588 bounding membrane of organelle; GO:0048475 coated membrane; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0044463 cell projection part; GO:0030135 coated vesicle; GO:0030665 clathrin-coated vesicle membrane; GO:0033267 axon part; GO:0098852 lytic vacuole membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0030424 axon; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:1904115 axon cytoplasm; GO:0030131 clathrin adaptor complex; GO:0044437 vacuolar part; GO:0030118 clathrin coat; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0030117 membrane coat; GO:0005794 Golgi apparatus; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0019902 phosphatase binding; GO:0019903 protein phosphatase binding; GO:0030742 GTP-dependent protein binding; GO:0019899 enzyme binding; GO:0005488 binding; ","K12397","AP3B; AP-3 complex subunit beta","hsa04142 Lysosome - Homo sapiens (human); ","IPR015151; IPR011989; IPR029394; IPR016024; IPR029390; IPR002553; ","\"Beta-adaptin appendage, C-terminal subdomain; Armadillo-like helical; AP-3 complex subunit beta 1, serine-rich domain; Armadillo-type fold; AP-3 complex subunit beta, C-terminal domain; Clathrin/coatomer adaptor, adaptin-like, N-terminal; \"\r"]
["O00204","Sulfotransferase family cytosolic 2B member 1 OS=Homo sapiens OX=9606 GN=SULT2B1","SULT2B1",41.307,18.708,13.2,4,5,4,0.866,0.816,0.917,1.143,1.094,1.147,1.302,2E-3,"cyto_nucl\r","GO:0000103 sulfate assimilation; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0009259 ribonucleotide metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0034032 purine nucleoside bisphosphate metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0019693 ribose phosphate metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009119 ribonucleoside metabolic process; GO:0009987 cellular process; GO:0006629 lipid metabolic process; GO:0006790 sulfur compound metabolic process; GO:0033865 nucleoside bisphosphate metabolic process; GO:0044281 small molecule metabolic process; GO:0008202 steroid metabolic process; GO:0044763 single-organism cellular process; GO:0033875 ribonucleoside bisphosphate metabolic process; GO:0072521 purine-containing compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:0006163 purine nucleotide metabolic process; GO:0046128 purine ribonucleoside metabolic process; GO:0006793 phosphorus metabolic process; GO:0034035 purine ribonucleoside bisphosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0006082 organic acid metabolic process; GO:0043436 oxoacid metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process; ","GO:0043229 intracellular organelle; GO:0005783 endoplasmic reticulum; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0050294 steroid sulfotransferase activity; GO:0008146 sulfotransferase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0004027 alcohol sulfotransferase activity; GO:0005515 protein binding; GO:0016782 transferase activity, transferring sulfur-containing groups; GO:0016740 transferase activity; ","K01015","SULT2B1; alcohol sulfotransferase [EC:2.8.2.2]","hsa00140 Steroid hormone biosynthesis - Homo sapiens (human); ","IPR000863; IPR027417; ","Sulfotransferase domain; P-loop containing nucleoside triphosphate hydrolase; \r"]
["O00214","Galectin-8 OS=Homo sapiens OX=9606 GN=LGALS8","LGALS8",35.808,2.6246,2.8,1,1,1,1.065,0.666,1.08,0.813,1.14,1.218,1.128,0.558,"cytoplasm\r","GO:0006950 response to stress; GO:0098542 defense response to other organism; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0044764 multi-organism cellular process; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0006914 autophagy; GO:0051707 response to other organism; GO:0044237 cellular metabolic process; GO:0051704 multi-organism process; GO:0009607 response to biotic stimulus; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0016032 viral process; GO:0044248 cellular catabolic process; GO:0098792 xenophagy; GO:0006952 defense response; GO:0044419 interspecies interaction between organisms; GO:0098586 cellular response to virus; GO:0009056 catabolic process; GO:0009987 cellular process; GO:0009615 response to virus; GO:0016236 macroautophagy; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0030246 carbohydrate binding; GO:0005515 protein binding; GO:0005488 binding; ","K06832",null,null,"IPR001079; IPR013320; ","\"Galectin, carbohydrate recognition domain; Concanavalin A-like lectin/glucanase domain; \"\r"]
["O00217","NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS8","NDUFS8",23.705,9.9744,19,4,6,4,1.041,1.042,1.093,1.014,0.828,0.999,0.895,0.161,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0006753 nucleoside phosphate metabolic process; GO:0007005 mitochondrion organization; GO:0006979 response to oxidative stress; GO:0019693 ribose phosphate metabolic process; GO:0071822 protein complex subunit organization; GO:0010257 NADH dehydrogenase complex assembly; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006119 oxidative phosphorylation; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0006120 mitochondrial electron transport, NADH to ubiquinone; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0097031 mitochondrial respiratory chain complex I biogenesis; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0022900 electron transport chain; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0070271 protein complex biogenesis; GO:0033108 mitochondrial respiratory chain complex assembly; GO:0016310 phosphorylation; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0042773 ATP synthesis coupled electron transport; GO:0009259 ribonucleotide metabolic process; GO:0022904 respiratory electron transport chain; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0032981 mitochondrial respiratory chain complex I assembly; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009119 ribonucleoside metabolic process; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0043623 cellular protein complex assembly; GO:0046034 ATP metabolic process; GO:0034622 cellular macromolecular complex assembly; GO:0006950 response to stress; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0045333 cellular respiration; GO:0006163 purine nucleotide metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0046128 purine ribonucleoside metabolic process; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:0071840 cellular component organization or biogenesis; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0045271 respiratory chain complex I; GO:0032991 macromolecular complex; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0005747 mitochondrial respiratory chain complex I; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0098803 respiratory chain complex; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005759 mitochondrial matrix; GO:0044429 mitochondrial part; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0005739 mitochondrion; GO:0005746 mitochondrial respiratory chain; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0030964 NADH dehydrogenase complex; GO:0031975 envelope; GO:1990204 oxidoreductase complex; GO:0043234 protein complex; GO:0031966 mitochondrial membrane; GO:0070469 respiratory chain; GO:0044444 cytoplasmic part; ","GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:0003954 NADH dehydrogenase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0051536 iron-sulfur cluster binding; GO:0043167 ion binding; GO:0050136 NADH dehydrogenase (quinone) activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0051539 4 iron, 4 sulfur cluster binding; GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; GO:0008137 NADH dehydrogenase (ubiquinone) activity; GO:0016491 oxidoreductase activity; GO:0051540 metal cluster binding; ","K03941","NDUFS8; NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:1.6.5.3 1.6.99.3]","hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); ","IPR017896; ","\"4Fe-4S ferredoxin-type, iron-sulphur binding domain; \"\r"]
["O00231","26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11","PSMD11",47.463,102.27,42.2,15,24,15,0.898,0.885,0.94,1.116,1.103,1.101,1.219,0.00044,"cytoplasm\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0010608 posttranscriptional regulation of gene expression; GO:0051443 positive regulation of ubiquitin-protein transferase activity; GO:0031347 regulation of defense response; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:1903364 positive regulation of cellular protein catabolic process; GO:0008152 metabolic process; GO:0065003 macromolecular complex assembly; GO:0044093 positive regulation of molecular function; GO:0090263 positive regulation of canonical Wnt signaling pathway; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0016055 Wnt signaling pathway; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0006521 regulation of cellular amino acid metabolic process; GO:0080090 regulation of primary metabolic process; GO:0010972 negative regulation of G2/M transition of mitotic cell cycle; GO:0044763 single-organism cellular process; GO:0060828 regulation of canonical Wnt signaling pathway; GO:0043086 negative regulation of catalytic activity; GO:0033209 tumor necrosis factor-mediated signaling pathway; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0000165 MAPK cascade; GO:1901575 organic substance catabolic process; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0007267 cell-cell signaling; GO:0002223 stimulatory C-type lectin receptor signaling pathway; GO:0030163 protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0060071 Wnt signaling pathway, planar cell polarity pathway; GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0016310 phosphorylation; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0043487 regulation of RNA stability; GO:0000209 protein polyubiquitination; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0009889 regulation of biosynthetic process; GO:0009896 positive regulation of catabolic process; GO:0043620 regulation of DNA-templated transcription in response to stress; GO:0070482 response to oxygen levels; GO:0044248 cellular catabolic process; GO:0042176 regulation of protein catabolic process; GO:0038093 Fc receptor signaling pathway; GO:0050778 positive regulation of immune response; GO:0023014 signal transduction by protein phosphorylation; GO:0006950 response to stress; GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; GO:0016567 protein ubiquitination; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0002263 cell activation involved in immune response; GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress; GO:1903321 negative regulation of protein modification by small protein conjugation or removal; GO:0045055 regulated exocytosis; GO:0031398 positive regulation of protein ubiquitination; GO:0032446 protein modification by small protein conjugation; GO:0031325 positive regulation of cellular metabolic process; GO:0048863 stem cell differentiation; GO:0030177 positive regulation of Wnt signaling pathway; GO:1904668 positive regulation of ubiquitin protein ligase activity; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0006955 immune response; GO:0043412 macromolecule modification; GO:0070646 protein modification by small protein removal; GO:0009968 negative regulation of signal transduction; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:0031331 positive regulation of cellular catabolic process; GO:0044699 single-organism process; GO:0031400 negative regulation of protein modification process; GO:0006796 phosphate-containing compound metabolic process; GO:0031396 regulation of protein ubiquitination; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0045930 negative regulation of mitotic cell cycle; GO:0009893 positive regulation of metabolic process; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0034612 response to tumor necrosis factor; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0051726 regulation of cell cycle; GO:0034097 response to cytokine; GO:0031326 regulation of cellular biosynthetic process; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0198738 cell-cell signaling by wnt; GO:0010565 regulation of cellular ketone metabolic process; GO:0032940 secretion by cell; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0070271 protein complex biogenesis; GO:0036211 protein modification process; GO:0090175 regulation of establishment of planar polarity; GO:0016043 cellular component organization; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0045786 negative regulation of cell cycle; GO:0044257 cellular protein catabolic process; GO:1901988 negative regulation of cell cycle phase transition; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0010498 proteasomal protein catabolic process; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0045862 positive regulation of proteolysis; GO:2000027 regulation of organ morphogenesis; GO:0006468 protein phosphorylation; GO:0023056 positive regulation of signaling; GO:0001666 response to hypoxia; GO:0002757 immune response-activating signal transduction; GO:0010647 positive regulation of cell communication; GO:0071453 cellular response to oxygen levels; GO:0019221 cytokine-mediated signaling pathway; GO:0043623 cellular protein complex assembly; GO:0031397 negative regulation of protein ubiquitination; GO:0034622 cellular macromolecular complex assembly; GO:0006355 regulation of transcription, DNA-templated; GO:0035556 intracellular signal transduction; GO:0019941 modification-dependent protein catabolic process; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia; GO:1902749 regulation of cell cycle G2/M phase transition; GO:0043488 regulation of mRNA stability; GO:0043085 positive regulation of catalytic activity; GO:0043933 macromolecular complex subunit organization; GO:0002366 leukocyte activation involved in immune response; GO:0019882 antigen processing and presentation; GO:0042119 neutrophil activation; GO:0050852 T cell receptor signaling pathway; GO:0002684 positive regulation of immune system process; GO:0038095 Fc-epsilon receptor signaling pathway; GO:0051248 negative regulation of protein metabolic process; GO:0022402 cell cycle process; GO:1902750 negative regulation of cell cycle G2/M phase transition; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0045321 leukocyte activation; GO:0002220 innate immune response activating cell surface receptor signaling pathway; GO:0007166 cell surface receptor signaling pathway; GO:0071345 cellular response to cytokine stimulus; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0051347 positive regulation of transferase activity; GO:1903362 regulation of cellular protein catabolic process; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0002443 leukocyte mediated immunity; GO:0002758 innate immune response-activating signal transduction; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0031323 regulation of cellular metabolic process; GO:2000058 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0010948 negative regulation of cell cycle process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0002682 regulation of immune system process; GO:0031145 anaphase-promoting complex-dependent catabolic process; GO:0050794 regulation of cellular process; GO:0043248 proteasome assembly; GO:0033554 cellular response to stress; GO:0007346 regulation of mitotic cell cycle; GO:0002283 neutrophil activation involved in immune response; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:0051239 regulation of multicellular organismal process; GO:0031349 positive regulation of defense response; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:1901987 regulation of cell cycle phase transition; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0010389 regulation of G2/M transition of mitotic cell cycle; GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; GO:0009966 regulation of signal transduction; GO:0006461 protein complex assembly; GO:0038061 NIK/NF-kappaB signaling; GO:0071456 cellular response to hypoxia; GO:0002253 activation of immune response; GO:0016192 vesicle-mediated transport; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1904666 regulation of ubiquitin protein ligase activity; GO:0055085 transmembrane transport; GO:0051247 positive regulation of protein metabolic process; GO:0051438 regulation of ubiquitin-protein transferase activity; GO:0030111 regulation of Wnt signaling pathway; GO:0006793 phosphorus metabolic process; GO:0001775 cell activation; GO:0036293 response to decreased oxygen levels; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process; GO:0006887 exocytosis; GO:0051444 negative regulation of ubiquitin-protein transferase activity; GO:0090090 negative regulation of canonical Wnt signaling pathway; GO:0051234 establishment of localization; GO:0035567 non-canonical Wnt signaling pathway; GO:1905330 regulation of morphogenesis of an epithelium; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:1901991 negative regulation of mitotic cell cycle phase transition; GO:0022607 cellular component assembly; GO:0045088 regulation of innate immune response; GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I; GO:0070887 cellular response to chemical stimulus; GO:0002274 myeloid leukocyte activation; GO:0050851 antigen receptor-mediated signaling pathway; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0071822 protein complex subunit organization; GO:0030178 negative regulation of Wnt signaling pathway; GO:0048002 antigen processing and presentation of peptide antigen; GO:0002446 neutrophil mediated immunity; GO:0048522 positive regulation of cellular process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0051348 negative regulation of transferase activity; GO:0070647 protein modification by small protein conjugation or removal; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0042221 response to chemical; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0019222 regulation of metabolic process; GO:0043299 leukocyte degranulation; GO:2000026 regulation of multicellular organismal development; GO:1904667 negative regulation of ubiquitin protein ligase activity; GO:0002218 activation of innate immune response; GO:0002252 immune effector process; GO:0071356 cellular response to tumor necrosis factor; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0016579 protein deubiquitination; GO:1903322 positive regulation of protein modification by small protein conjugation or removal; GO:0006508 proteolysis; GO:0036230 granulocyte activation; GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:0009987 cellular process; GO:0033238 regulation of cellular amine metabolic process; GO:0043632 modification-dependent macromolecule catabolic process; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0045089 positive regulation of innate immune response; GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition; GO:0031401 positive regulation of protein modification process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0009057 macromolecule catabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0009967 positive regulation of signal transduction; GO:0045732 positive regulation of protein catabolic process; GO:0036294 cellular response to decreased oxygen levels; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0034774 secretory granule lumen; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005838 proteasome regulatory particle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:1905369 endopeptidase complex; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:1902494 catalytic complex; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0022624 proteasome accessory complex; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:1905368 peptidase complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0008541 proteasome regulatory particle, lid subcomplex; GO:0000502 proteasome complex; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0005198 structural molecule activity; GO:0005488 binding; ","K03036","PSMD11; 26S proteasome regulatory subunit N6","hsa03050 Proteasome - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); ","IPR000717; IPR011991; IPR011990; ","Proteasome component (PCI) domain; Winged helix-turn-helix DNA-binding domain; Tetratricopeptide-like helical domain; \r"]
["O00232","26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12","PSMD12",52.904,104.41,39.9,16,26,16,0.9,0.913,0.912,1.085,1.067,1.056,1.177,5.89e-05,"cytoplasm\r","GO:0044700 single organism signaling; GO:0010608 posttranscriptional regulation of gene expression; GO:0051443 positive regulation of ubiquitin-protein transferase activity; GO:0031347 regulation of defense response; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:1903364 positive regulation of cellular protein catabolic process; GO:0008152 metabolic process; GO:0044093 positive regulation of molecular function; GO:0090263 positive regulation of canonical Wnt signaling pathway; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0016055 Wnt signaling pathway; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0006521 regulation of cellular amino acid metabolic process; GO:0080090 regulation of primary metabolic process; GO:0010972 negative regulation of G2/M transition of mitotic cell cycle; GO:0044763 single-organism cellular process; GO:0060828 regulation of canonical Wnt signaling pathway; GO:0043086 negative regulation of catalytic activity; GO:0033209 tumor necrosis factor-mediated signaling pathway; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0000165 MAPK cascade; GO:1901575 organic substance catabolic process; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0007267 cell-cell signaling; GO:0002223 stimulatory C-type lectin receptor signaling pathway; GO:0030163 protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0060071 Wnt signaling pathway, planar cell polarity pathway; GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0016310 phosphorylation; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0043487 regulation of RNA stability; GO:0000209 protein polyubiquitination; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0009889 regulation of biosynthetic process; GO:0009896 positive regulation of catabolic process; GO:0043620 regulation of DNA-templated transcription in response to stress; GO:0070482 response to oxygen levels; GO:0044248 cellular catabolic process; GO:0042176 regulation of protein catabolic process; GO:0038093 Fc receptor signaling pathway; GO:0050778 positive regulation of immune response; GO:0023014 signal transduction by protein phosphorylation; GO:0006950 response to stress; GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; GO:0016567 protein ubiquitination; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress; GO:0002263 cell activation involved in immune response; GO:1903321 negative regulation of protein modification by small protein conjugation or removal; GO:0045055 regulated exocytosis; GO:0031398 positive regulation of protein ubiquitination; GO:0032446 protein modification by small protein conjugation; GO:0031325 positive regulation of cellular metabolic process; GO:0030177 positive regulation of Wnt signaling pathway; GO:1904668 positive regulation of ubiquitin protein ligase activity; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0006955 immune response; GO:0043412 macromolecule modification; GO:0070646 protein modification by small protein removal; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0031331 positive regulation of cellular catabolic process; GO:0044699 single-organism process; GO:0031400 negative regulation of protein modification process; GO:0006796 phosphate-containing compound metabolic process; GO:0031396 regulation of protein ubiquitination; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0045930 negative regulation of mitotic cell cycle; GO:0009893 positive regulation of metabolic process; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0034612 response to tumor necrosis factor; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0051726 regulation of cell cycle; GO:0034097 response to cytokine; GO:0031326 regulation of cellular biosynthetic process; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0198738 cell-cell signaling by wnt; GO:0010565 regulation of cellular ketone metabolic process; GO:0032940 secretion by cell; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0036211 protein modification process; GO:0090175 regulation of establishment of planar polarity; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0045786 negative regulation of cell cycle; GO:0044257 cellular protein catabolic process; GO:1901988 negative regulation of cell cycle phase transition; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0010498 proteasomal protein catabolic process; GO:0071704 organic substance metabolic process; GO:0045862 positive regulation of proteolysis; GO:2000027 regulation of organ morphogenesis; GO:0006468 protein phosphorylation; GO:0023056 positive regulation of signaling; GO:0001666 response to hypoxia; GO:0002757 immune response-activating signal transduction; GO:0010647 positive regulation of cell communication; GO:0071453 cellular response to oxygen levels; GO:0019221 cytokine-mediated signaling pathway; GO:0031397 negative regulation of protein ubiquitination; GO:0006355 regulation of transcription, DNA-templated; GO:0035556 intracellular signal transduction; GO:0019941 modification-dependent protein catabolic process; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia; GO:1902749 regulation of cell cycle G2/M phase transition; GO:0043488 regulation of mRNA stability; GO:0043085 positive regulation of catalytic activity; GO:0002366 leukocyte activation involved in immune response; GO:0019882 antigen processing and presentation; GO:0042119 neutrophil activation; GO:0050852 T cell receptor signaling pathway; GO:0002684 positive regulation of immune system process; GO:0038095 Fc-epsilon receptor signaling pathway; GO:0051248 negative regulation of protein metabolic process; GO:0022402 cell cycle process; GO:1902750 negative regulation of cell cycle G2/M phase transition; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0045321 leukocyte activation; GO:0002220 innate immune response activating cell surface receptor signaling pathway; GO:0007166 cell surface receptor signaling pathway; GO:0071345 cellular response to cytokine stimulus; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0051347 positive regulation of transferase activity; GO:1903362 regulation of cellular protein catabolic process; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0002443 leukocyte mediated immunity; GO:0002758 innate immune response-activating signal transduction; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0031323 regulation of cellular metabolic process; GO:2000058 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0010948 negative regulation of cell cycle process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0002682 regulation of immune system process; GO:0031145 anaphase-promoting complex-dependent catabolic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0007346 regulation of mitotic cell cycle; GO:0002283 neutrophil activation involved in immune response; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:0051239 regulation of multicellular organismal process; GO:0031349 positive regulation of defense response; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:1901987 regulation of cell cycle phase transition; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0010389 regulation of G2/M transition of mitotic cell cycle; GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; GO:0009966 regulation of signal transduction; GO:0038061 NIK/NF-kappaB signaling; GO:0071456 cellular response to hypoxia; GO:0002253 activation of immune response; GO:0016192 vesicle-mediated transport; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1904666 regulation of ubiquitin protein ligase activity; GO:0055085 transmembrane transport; GO:0051247 positive regulation of protein metabolic process; GO:0051438 regulation of ubiquitin-protein transferase activity; GO:0030111 regulation of Wnt signaling pathway; GO:0006793 phosphorus metabolic process; GO:0001775 cell activation; GO:0036293 response to decreased oxygen levels; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process; GO:0006887 exocytosis; GO:0051444 negative regulation of ubiquitin-protein transferase activity; GO:0090090 negative regulation of canonical Wnt signaling pathway; GO:0051234 establishment of localization; GO:0035567 non-canonical Wnt signaling pathway; GO:1905330 regulation of morphogenesis of an epithelium; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:1901991 negative regulation of mitotic cell cycle phase transition; GO:0045088 regulation of innate immune response; GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I; GO:0070887 cellular response to chemical stimulus; GO:0002274 myeloid leukocyte activation; GO:0050851 antigen receptor-mediated signaling pathway; GO:0010468 regulation of gene expression; GO:0030178 negative regulation of Wnt signaling pathway; GO:0048002 antigen processing and presentation of peptide antigen; GO:0002446 neutrophil mediated immunity; GO:0048522 positive regulation of cellular process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0051348 negative regulation of transferase activity; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0019222 regulation of metabolic process; GO:0043299 leukocyte degranulation; GO:2000026 regulation of multicellular organismal development; GO:0002218 activation of innate immune response; GO:1904667 negative regulation of ubiquitin protein ligase activity; GO:0002252 immune effector process; GO:0071356 cellular response to tumor necrosis factor; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0016579 protein deubiquitination; GO:0050896 response to stimulus; GO:1903322 positive regulation of protein modification by small protein conjugation or removal; GO:0006508 proteolysis; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:0033238 regulation of cellular amine metabolic process; GO:0043632 modification-dependent macromolecule catabolic process; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0045089 positive regulation of innate immune response; GO:0031401 positive regulation of protein modification process; GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0051246 regulation of protein metabolic process; GO:0009057 macromolecule catabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0009967 positive regulation of signal transduction; GO:0045732 positive regulation of protein catabolic process; GO:0036294 cellular response to decreased oxygen levels; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0034774 secretory granule lumen; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005838 proteasome regulatory particle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:1905369 endopeptidase complex; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:1902494 catalytic complex; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0022624 proteasome accessory complex; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:1905368 peptidase complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0008541 proteasome regulatory particle, lid subcomplex; GO:0000502 proteasome complex; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0031595 nuclear proteasome complex; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0005488 binding; ","K03035","PSMD12; 26S proteasome regulatory subunit N5","hsa03050 Proteasome - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); ","IPR011991; IPR000717; ","Winged helix-turn-helix DNA-binding domain; Proteasome component (PCI) domain; \r"]
["O00233","26S proteasome non-ATPase regulatory subunit 9 OS=Homo sapiens OX=9606 GN=PSMD9","PSMD9",24.682,25.162,35.4,7,9,7,0.942,0.977,0.964,1.107,1.037,1.024,1.099,0.0237,"cytoskeleton\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0010608 posttranscriptional regulation of gene expression; GO:0051443 positive regulation of ubiquitin-protein transferase activity; GO:0050796 regulation of insulin secretion; GO:0009891 positive regulation of biosynthetic process; GO:0002793 positive regulation of peptide secretion; GO:0031347 regulation of defense response; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:1903364 positive regulation of cellular protein catabolic process; GO:0008152 metabolic process; GO:0065003 macromolecular complex assembly; GO:0044093 positive regulation of molecular function; GO:0090263 positive regulation of canonical Wnt signaling pathway; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0016055 Wnt signaling pathway; GO:0051051 negative regulation of transport; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0050709 negative regulation of protein secretion; GO:0006521 regulation of cellular amino acid metabolic process; GO:0080090 regulation of primary metabolic process; GO:0010972 negative regulation of G2/M transition of mitotic cell cycle; GO:1903531 negative regulation of secretion by cell; GO:0044763 single-organism cellular process; GO:0060828 regulation of canonical Wnt signaling pathway; GO:0043086 negative regulation of catalytic activity; GO:0033209 tumor necrosis factor-mediated signaling pathway; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0000165 MAPK cascade; GO:1901575 organic substance catabolic process; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0007267 cell-cell signaling; GO:0002223 stimulatory C-type lectin receptor signaling pathway; GO:0030163 protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0060071 Wnt signaling pathway, planar cell polarity pathway; GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:0051223 regulation of protein transport; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0016310 phosphorylation; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0090277 positive regulation of peptide hormone secretion; GO:0043487 regulation of RNA stability; GO:0000209 protein polyubiquitination; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0009889 regulation of biosynthetic process; GO:0009896 positive regulation of catabolic process; GO:0043620 regulation of DNA-templated transcription in response to stress; GO:0070482 response to oxygen levels; GO:0044248 cellular catabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0042176 regulation of protein catabolic process; GO:0038093 Fc receptor signaling pathway; GO:0050778 positive regulation of immune response; GO:0023014 signal transduction by protein phosphorylation; GO:0006950 response to stress; GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; GO:0016567 protein ubiquitination; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:1903321 negative regulation of protein modification by small protein conjugation or removal; GO:0046888 negative regulation of hormone secretion; GO:0031398 positive regulation of protein ubiquitination; GO:0032446 protein modification by small protein conjugation; GO:0031325 positive regulation of cellular metabolic process; GO:0030177 positive regulation of Wnt signaling pathway; GO:1904668 positive regulation of ubiquitin protein ligase activity; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0043412 macromolecule modification; GO:0070646 protein modification by small protein removal; GO:0009968 negative regulation of signal transduction; GO:0031331 positive regulation of cellular catabolic process; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0051046 regulation of secretion; GO:0031400 negative regulation of protein modification process; GO:0006796 phosphate-containing compound metabolic process; GO:0031396 regulation of protein ubiquitination; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0045930 negative regulation of mitotic cell cycle; GO:0090278 negative regulation of peptide hormone secretion; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0034612 response to tumor necrosis factor; GO:0051726 regulation of cell cycle; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0034097 response to cytokine; GO:0031326 regulation of cellular biosynthetic process; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:1903530 regulation of secretion by cell; GO:0010605 negative regulation of macromolecule metabolic process; GO:0198738 cell-cell signaling by wnt; GO:0010565 regulation of cellular ketone metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0036211 protein modification process; GO:0070271 protein complex biogenesis; GO:0051222 positive regulation of protein transport; GO:0090175 regulation of establishment of planar polarity; GO:0016043 cellular component organization; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0045786 negative regulation of cell cycle; GO:0044257 cellular protein catabolic process; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:1901988 negative regulation of cell cycle phase transition; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0010498 proteasomal protein catabolic process; GO:0071704 organic substance metabolic process; GO:0045862 positive regulation of proteolysis; GO:2000027 regulation of organ morphogenesis; GO:0006468 protein phosphorylation; GO:0023056 positive regulation of signaling; GO:0001666 response to hypoxia; GO:0002757 immune response-activating signal transduction; GO:0010647 positive regulation of cell communication; GO:0071453 cellular response to oxygen levels; GO:0019221 cytokine-mediated signaling pathway; GO:0043623 cellular protein complex assembly; GO:0031397 negative regulation of protein ubiquitination; GO:0034622 cellular macromolecular complex assembly; GO:0032024 positive regulation of insulin secretion; GO:0006355 regulation of transcription, DNA-templated; GO:0035556 intracellular signal transduction; GO:0019941 modification-dependent protein catabolic process; GO:0051049 regulation of transport; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia; GO:1902749 regulation of cell cycle G2/M phase transition; GO:0043488 regulation of mRNA stability; GO:0043085 positive regulation of catalytic activity; GO:0043933 macromolecular complex subunit organization; GO:0019882 antigen processing and presentation; GO:0050852 T cell receptor signaling pathway; GO:0002684 positive regulation of immune system process; GO:0038095 Fc-epsilon receptor signaling pathway; GO:0051248 negative regulation of protein metabolic process; GO:1904950 negative regulation of establishment of protein localization; GO:0022402 cell cycle process; GO:1902750 negative regulation of cell cycle G2/M phase transition; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0002220 innate immune response activating cell surface receptor signaling pathway; GO:0007166 cell surface receptor signaling pathway; GO:0071345 cellular response to cytokine stimulus; GO:0032879 regulation of localization; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0051347 positive regulation of transferase activity; GO:1903362 regulation of cellular protein catabolic process; GO:0002758 innate immune response-activating signal transduction; GO:0031329 regulation of cellular catabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0009894 regulation of catabolic process; GO:0031323 regulation of cellular metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:2000058 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0046883 regulation of hormone secretion; GO:0010948 negative regulation of cell cycle process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0050714 positive regulation of protein secretion; GO:0010817 regulation of hormone levels; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0002682 regulation of immune system process; GO:0031145 anaphase-promoting complex-dependent catabolic process; GO:0051047 positive regulation of secretion; GO:0050794 regulation of cellular process; GO:0043248 proteasome assembly; GO:0033554 cellular response to stress; GO:0007346 regulation of mitotic cell cycle; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:0051239 regulation of multicellular organismal process; GO:0031349 positive regulation of defense response; GO:1901987 regulation of cell cycle phase transition; GO:0010628 positive regulation of gene expression; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0010389 regulation of G2/M transition of mitotic cell cycle; GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; GO:0032880 regulation of protein localization; GO:0009966 regulation of signal transduction; GO:0006461 protein complex assembly; GO:0070682 proteasome regulatory particle assembly; GO:0038061 NIK/NF-kappaB signaling; GO:0071456 cellular response to hypoxia; GO:0090087 regulation of peptide transport; GO:0002253 activation of immune response; GO:0051254 positive regulation of RNA metabolic process; GO:0051224 negative regulation of protein transport; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1904666 regulation of ubiquitin protein ligase activity; GO:0055085 transmembrane transport; GO:0051247 positive regulation of protein metabolic process; GO:1904951 positive regulation of establishment of protein localization; GO:0051438 regulation of ubiquitin-protein transferase activity; GO:0030111 regulation of Wnt signaling pathway; GO:0006793 phosphorus metabolic process; GO:0046887 positive regulation of hormone secretion; GO:0036293 response to decreased oxygen levels; GO:0048584 positive regulation of response to stimulus; GO:0031328 positive regulation of cellular biosynthetic process; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process; GO:0051444 negative regulation of ubiquitin-protein transferase activity; GO:0090090 negative regulation of canonical Wnt signaling pathway; GO:0051234 establishment of localization; GO:0035567 non-canonical Wnt signaling pathway; GO:1905330 regulation of morphogenesis of an epithelium; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:1901991 negative regulation of mitotic cell cycle phase transition; GO:0045088 regulation of innate immune response; GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I; GO:0070887 cellular response to chemical stimulus; GO:0050851 antigen receptor-mediated signaling pathway; GO:0010468 regulation of gene expression; GO:0071822 protein complex subunit organization; GO:0030178 negative regulation of Wnt signaling pathway; GO:0048002 antigen processing and presentation of peptide antigen; GO:0048522 positive regulation of cellular process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0051348 negative regulation of transferase activity; GO:0070647 protein modification by small protein conjugation or removal; GO:0002792 negative regulation of peptide secretion; GO:0051050 positive regulation of transport; GO:0051048 negative regulation of secretion; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0042221 response to chemical; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:1903532 positive regulation of secretion by cell; GO:0019222 regulation of metabolic process; GO:2000026 regulation of multicellular organismal development; GO:1904667 negative regulation of ubiquitin protein ligase activity; GO:0002218 activation of innate immune response; GO:0071356 cellular response to tumor necrosis factor; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0016579 protein deubiquitination; GO:0070201 regulation of establishment of protein localization; GO:0002791 regulation of peptide secretion; GO:1903322 positive regulation of protein modification by small protein conjugation or removal; GO:0006508 proteolysis; GO:0050708 regulation of protein secretion; GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:0009987 cellular process; GO:0033238 regulation of cellular amine metabolic process; GO:0043632 modification-dependent macromolecule catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0045089 positive regulation of innate immune response; GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition; GO:0031401 positive regulation of protein modification process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0051246 regulation of protein metabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0009057 macromolecule catabolic process; GO:0090276 regulation of peptide hormone secretion; GO:0046676 negative regulation of insulin secretion; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0009967 positive regulation of signal transduction; GO:0045732 positive regulation of protein catabolic process; GO:0036294 cellular response to decreased oxygen levels; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0000502 proteasome complex; GO:0005838 proteasome regulatory particle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:1905369 endopeptidase complex; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0022624 proteasome accessory complex; GO:0005622 intracellular; GO:0044464 cell part; GO:1905368 peptidase complex; GO:0043227 membrane-bounded organelle; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0000989 transcription factor activity, transcription factor binding; GO:0003713 transcription coactivator activity; GO:0043425 bHLH transcription factor binding; GO:0005515 protein binding; GO:0003712 transcription cofactor activity; GO:0000988 transcription factor activity, protein binding; GO:0008134 transcription factor binding; GO:0005488 binding; ","K06693",null,null,"IPR001478; ","PDZ domain; \r"]
["O00244","Copper transport protein ATOX1 OS=Homo sapiens OX=9606 GN=ATOX1","ATOX1",7.4016,13.065,38.2,2,2,2,0.937,0.921,0.923,1.096,1.127,0.997,1.158,0.0606,"extracellular\r","GO:0046907 intracellular transport; GO:0065008 regulation of biological quality; GO:0034220 ion transmembrane transport; GO:0055076 transition metal ion homeostasis; GO:0030001 metal ion transport; GO:0030003 cellular cation homeostasis; GO:0035434 copper ion transmembrane transport; GO:0044699 single-organism process; GO:0006959 humoral immune response; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0055082 cellular chemical homeostasis; GO:0009607 response to biotic stimulus; GO:0051234 establishment of localization; GO:0000041 transition metal ion transport; GO:0009605 response to external stimulus; GO:0042592 homeostatic process; GO:0051649 establishment of localization in cell; GO:0006812 cation transport; GO:0055080 cation homeostasis; GO:0006979 response to oxidative stress; GO:0055065 metal ion homeostasis; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0006878 cellular copper ion homeostasis; GO:0098655 cation transmembrane transport; GO:0006950 response to stress; GO:0050801 ion homeostasis; GO:0098660 inorganic ion transmembrane transport; GO:0019730 antimicrobial humoral response; GO:0006825 copper ion transport; GO:0044763 single-organism cellular process; GO:0098771 inorganic ion homeostasis; GO:0019725 cellular homeostasis; GO:0002376 immune system process; GO:0051704 multi-organism process; GO:0051641 cellular localization; GO:0046916 cellular transition metal ion homeostasis; GO:0055070 copper ion homeostasis; GO:0006810 transport; GO:0055085 transmembrane transport; GO:0015680 intracellular copper ion transport; GO:0006873 cellular ion homeostasis; GO:0006811 ion transport; GO:0006875 cellular metal ion homeostasis; GO:0051179 localization; GO:0006955 immune response; GO:0098662 inorganic cation transmembrane transport; GO:0065007 biological regulation; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:0015075 ion transmembrane transporter activity; GO:0005375 copper ion transmembrane transporter activity; GO:0051117 ATPase binding; GO:0043167 ion binding; GO:0046915 transition metal ion transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0016530 metallochaperone activity; GO:0005515 protein binding; GO:0005507 copper ion binding; GO:0022891 substrate-specific transmembrane transporter activity; GO:0046873 metal ion transmembrane transporter activity; GO:0046914 transition metal ion binding; GO:0005488 binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0032767 copper-dependent protein binding; GO:0022890 inorganic cation transmembrane transporter activity; GO:0016531 copper chaperone activity; GO:0019899 enzyme binding; GO:0008324 cation transmembrane transporter activity; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; ","K07213","ATOX1; copper chaperone","hsa04978 Mineral absorption - Homo sapiens (human); ","IPR006121; ","\"Heavy metal-associated domain, HMA; \"\r"]
["O00264","Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1","PGRMC1",21.671,43.524,35.9,7,10,6,1.161,1.173,1.024,0.874,0.905,0.945,0.811,0.0134,"nucleus\r","GO:0045321 leukocyte activation; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0051234 establishment of localization; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0002274 myeloid leukocyte activation; GO:0002443 leukocyte mediated immunity; GO:0016192 vesicle-mediated transport; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0002376 immune system process; GO:0043312 neutrophil degranulation; GO:0002263 cell activation involved in immune response; GO:0002444 myeloid leukocyte mediated immunity; GO:0002366 leukocyte activation involved in immune response; GO:0006810 transport; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0032940 secretion by cell; GO:0001775 cell activation; GO:0043299 leukocyte degranulation; GO:0006955 immune response; GO:0051179 localization; GO:0006887 exocytosis; ","GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0035579 specific granule membrane; GO:0005789 endoplasmic reticulum membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0030667 secretory granule membrane; GO:0044432 endoplasmic reticulum part; GO:0042581 specific granule; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0020037 heme binding; GO:0005488 binding; GO:0008289 lipid binding; GO:0005515 protein binding; GO:0046906 tetrapyrrole binding; GO:0005496 steroid binding; ","K17278",null,null,"IPR001199; ","Cytochrome b5-like heme/steroid binding domain; \r"]
["O00267","Transcription elongation factor SPT5 OS=Homo sapiens OX=9606 GN=SUPT5H","SUPT5H",121,3.5922,1.6,2,3,2,0.892,0.99,0.884,1.092,1.038,1.105,1.17,0.0185,"nucleus\r","GO:0019079 viral genome replication; GO:0097659 nucleic acid-templated transcription; GO:0009891 positive regulation of biosynthetic process; GO:0050686 negative regulation of mRNA processing; GO:0006354 DNA-templated transcription, elongation; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0031440 regulation of mRNA 3'-end processing; GO:0032784 regulation of DNA-templated transcription, elongation; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0006396 RNA processing; GO:0018130 heterocycle biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044763 single-organism cellular process; GO:0000122 negative regulation of transcription from RNA polymerase II promoter; GO:0032786 positive regulation of DNA-templated transcription, elongation; GO:0050684 regulation of mRNA processing; GO:0032774 RNA biosynthetic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0031323 regulation of cellular metabolic process; GO:0010506 regulation of autophagy; GO:0051704 multi-organism process; GO:0016241 regulation of macroautophagy; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050434 positive regulation of viral transcription; GO:0010508 positive regulation of autophagy; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0016239 positive regulation of macroautophagy; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0039694 viral RNA genome replication; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0006338 chromatin remodeling; GO:0006259 DNA metabolic process; GO:0039692 single stranded viral RNA replication via double stranded DNA intermediate; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0045892 negative regulation of transcription, DNA-templated; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0009896 positive regulation of catabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0051254 positive regulation of RNA metabolic process; GO:0006370 7-methylguanosine mRNA capping; GO:1900363 regulation of mRNA polyadenylation; GO:0043900 regulation of multi-organism process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006368 transcription elongation from RNA polymerase II promoter; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:1903311 regulation of mRNA metabolic process; GO:0046782 regulation of viral transcription; GO:0009890 negative regulation of biosynthetic process; GO:0032785 negative regulation of DNA-templated transcription, elongation; GO:0051276 chromosome organization; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0031331 positive regulation of cellular catabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:1903312 negative regulation of mRNA metabolic process; GO:0051253 negative regulation of RNA metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0039703 RNA replication; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0010468 regulation of gene expression; GO:1903902 positive regulation of viral life cycle; GO:0036260 RNA capping; GO:0043902 positive regulation of multi-organism process; GO:0031326 regulation of cellular biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:1902679 negative regulation of RNA biosynthetic process; GO:0019222 regulation of metabolic process; GO:1900364 negative regulation of mRNA polyadenylation; GO:0006325 chromatin organization; GO:0031441 negative regulation of mRNA 3'-end processing; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0009452 7-methylguanosine RNA capping; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0016032 viral process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0050792 regulation of viral process; GO:0006807 nitrogen compound metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0048524 positive regulation of viral process; GO:0006366 transcription from RNA polymerase II promoter; GO:0010467 gene expression; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0031327 negative regulation of cellular biosynthetic process; GO:1903900 regulation of viral life cycle; GO:0007049 cell cycle; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0032044 DSIF complex; GO:0043226 organelle; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0008023 transcription elongation factor complex; GO:0043227 membrane-bounded organelle; GO:0043234 protein complex; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0046982 protein heterodimerization activity; GO:0005488 binding; GO:0046983 protein dimerization activity; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0003682 chromatin binding; GO:0019899 enzyme binding; ","K15172",null,null,"IPR008991; IPR006645; IPR024945; IPR014722; IPR005824; IPR005100; IPR022581; ","\"Translation protein SH3-like domain; NusG, N-terminal; Spt5 C-terminal domain; Ribosomal protein L2 domain 2; KOW; Transcription elongation factor Spt5, NGN domain; Spt5 transcription elongation factor, N-terminal; \"\r"]
["O00273","DNA fragmentation factor subunit alpha OS=Homo sapiens OX=9606 GN=DFFA","DFFA",36.521,23.892,19.6,5,5,5,0.946,1.093,1.078,1.012,0.957,0.929,0.93,0.245,"nucleus\r","GO:0010941 regulation of cell death; GO:0006308 DNA catabolic process; GO:0051129 negative regulation of cellular component organization; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0030262 apoptotic nuclear changes; GO:0006915 apoptotic process; GO:1901361 organic cyclic compound catabolic process; GO:1902511 negative regulation of apoptotic DNA fragmentation; GO:0043170 macromolecule metabolic process; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:1900117 regulation of execution phase of apoptosis; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0010942 positive regulation of cell death; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0051052 regulation of DNA metabolic process; GO:0051053 negative regulation of DNA metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0097194 execution phase of apoptosis; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0090305 nucleic acid phosphodiester bond hydrolysis; GO:0060548 negative regulation of cell death; GO:0043068 positive regulation of programmed cell death; GO:0050794 regulation of cellular process; GO:0071887 leukocyte apoptotic process; GO:0016043 cellular component organization; GO:0043069 negative regulation of programmed cell death; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0006259 DNA metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0043067 regulation of programmed cell death; GO:0043065 positive regulation of apoptotic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0070231 T cell apoptotic process; GO:0006309 apoptotic DNA fragmentation; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0043066 negative regulation of apoptotic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0044248 cellular catabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009895 negative regulation of catabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0009987 cellular process; GO:0044265 cellular macromolecule catabolic process; GO:0070242 thymocyte apoptotic process; GO:0070227 lymphocyte apoptotic process; GO:1902510 regulation of apoptotic DNA fragmentation; GO:0006807 nitrogen compound metabolic process; GO:0006921 cellular component disassembly involved in execution phase of apoptosis; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0044238 primary metabolic process; GO:0000737 DNA catabolic process, endonucleolytic; GO:0048518 positive regulation of biological process; GO:0009892 negative regulation of metabolic process; GO:0031330 negative regulation of cellular catabolic process; GO:1900118 negative regulation of execution phase of apoptosis; GO:1903624 regulation of DNA catabolic process; GO:0008219 cell death; GO:0009057 macromolecule catabolic process; GO:0022411 cellular component disassembly; GO:0012501 programmed cell death; GO:0051128 regulation of cellular component organization; GO:1903625 negative regulation of DNA catabolic process; GO:0009056 catabolic process; GO:0042981 regulation of apoptotic process; GO:0046700 heterocycle catabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0005886 plasma membrane; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0000785 chromatin; GO:0044454 nuclear chromosome part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005694 chromosome; GO:0000790 nuclear chromatin; GO:0000228 nuclear chromosome; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0005488 binding; ","K02310","DFFA; DNA fragmentation factor, 45 kD, alpha subunit","hsa04210 Apoptosis - Homo sapiens (human); ","IPR027296; IPR015121; IPR003508; ","\"DNA fragmentation factor 45kDa C-terminal domain; DNA fragmentation factor 45kDa, middle domain; CIDE-N domain; \"\r"]
["O00291","Huntingtin-interacting protein 1 OS=Homo sapiens OX=9606 GN=HIP1","HIP1",116.22,23.444,6.8,6,6,6,0.981,1.029,0.983,1.011,1.084,0.921,1.008,0.915,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0060627 regulation of vesicle-mediated transport; GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0010941 regulation of cell death; GO:0032270 positive regulation of cellular protein metabolic process; GO:0051896 regulation of protein kinase B signaling; GO:0097659 nucleic acid-templated transcription; GO:0044237 cellular metabolic process; GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway; GO:0015031 protein transport; GO:0008152 metabolic process; GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway; GO:0065003 macromolecular complex assembly; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0043170 macromolecule metabolic process; GO:0008104 protein localization; GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0052548 regulation of endopeptidase activity; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0048259 regulation of receptor-mediated endocytosis; GO:0010950 positive regulation of endopeptidase activity; GO:0080090 regulation of primary metabolic process; GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway; GO:0044763 single-organism cellular process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0006810 transport; GO:1903506 regulation of nucleic acid-templated transcription; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0010952 positive regulation of peptidase activity; GO:0043068 positive regulation of programmed cell death; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0097190 apoptotic signaling pathway; GO:2001056 positive regulation of cysteine-type endopeptidase activity; GO:0043067 regulation of programmed cell death; GO:0099637 neurotransmitter receptor transport; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0051345 positive regulation of hydrolase activity; GO:0009889 regulation of biosynthetic process; GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway; GO:0051171 regulation of nitrogen compound metabolic process; GO:0006898 receptor-mediated endocytosis; GO:0007010 cytoskeleton organization; GO:0009966 regulation of signal transduction; GO:0006461 protein complex assembly; GO:0030100 regulation of endocytosis; GO:1902531 regulation of intracellular signal transduction; GO:0016192 vesicle-mediated transport; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0071702 organic substance transport; GO:0048268 clathrin coat assembly; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0045184 establishment of protein localization; GO:0051247 positive regulation of protein metabolic process; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0031325 positive regulation of cellular metabolic process; GO:0031647 regulation of protein stability; GO:0012501 programmed cell death; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0050821 protein stabilization; GO:0023051 regulation of signaling; GO:0048869 cellular developmental process; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0022607 cellular component assembly; GO:0006915 apoptotic process; GO:0033036 macromolecule localization; GO:2000586 regulation of platelet-derived growth factor receptor-beta signaling pathway; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0071822 protein complex subunit organization; GO:0031326 regulation of cellular biosynthetic process; GO:2000116 regulation of cysteine-type endopeptidase activity; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0023052 signaling; GO:0051050 positive regulation of transport; GO:0010942 positive regulation of cell death; GO:0016070 RNA metabolic process; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0052547 regulation of peptidase activity; GO:0070271 protein complex biogenesis; GO:0048260 positive regulation of receptor-mediated endocytosis; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0045807 positive regulation of endocytosis; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0043065 positive regulation of apoptotic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0045862 positive regulation of proteolysis; GO:0072583 clathrin-dependent endocytosis; GO:1901184 regulation of ERBB signaling pathway; GO:0023056 positive regulation of signaling; GO:0034641 cellular nitrogen compound metabolic process; GO:0010647 positive regulation of cell communication; GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0043623 cellular protein complex assembly; GO:0051897 positive regulation of protein kinase B signaling; GO:0034622 cellular macromolecular complex assembly; GO:1901186 positive regulation of ERBB signaling pathway; GO:0006355 regulation of transcription, DNA-templated; GO:0051049 regulation of transport; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0043085 positive regulation of catalytic activity; GO:0043933 macromolecular complex subunit organization; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0010467 gene expression; GO:0009967 positive regulation of signal transduction; GO:0042058 regulation of epidermal growth factor receptor signaling pathway; GO:0051128 regulation of cellular component organization; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0019898 extrinsic component of membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0031234 extrinsic component of cytoplasmic side of plasma membrane; GO:0098888 extrinsic component of presynaptic membrane; GO:0005623 cell; GO:0009898 cytoplasmic side of plasma membrane; GO:0098562 cytoplasmic side of membrane; GO:0042734 presynaptic membrane; GO:0044422 organelle part; GO:0030662 coated vesicle membrane; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0098590 plasma membrane region; GO:0030136 clathrin-coated vesicle; GO:0044425 membrane part; GO:0098793 presynapse; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0097060 synaptic membrane; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0044456 synapse part; GO:0098552 side of membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0019897 extrinsic component of plasma membrane; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0030665 clathrin-coated vesicle membrane; GO:0030135 coated vesicle; GO:0045202 synapse; GO:0005886 plasma membrane; GO:0045211 postsynaptic membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0098794 postsynapse; GO:0044459 plasma membrane part; GO:0005794 Golgi apparatus; GO:0098890 extrinsic component of postsynaptic membrane; GO:0044444 cytoplasmic part; ","GO:0035612 AP-2 adaptor complex binding; GO:0051015 actin filament binding; GO:0098748 endocytic adaptor activity; GO:0005102 receptor binding; GO:0046983 protein dimerization activity; GO:0080025 phosphatidylinositol-3,5-bisphosphate binding; GO:0005515 protein binding; GO:0032051 clathrin light chain binding; GO:1902936 phosphatidylinositol bisphosphate binding; GO:0030276 clathrin binding; GO:0042802 identical protein binding; GO:0008092 cytoskeletal protein binding; GO:0005488 binding; GO:0035091 phosphatidylinositol binding; GO:0008289 lipid binding; GO:0043168 anion binding; GO:1901981 phosphatidylinositol phosphate binding; GO:0030674 protein binding, bridging; GO:0046982 protein heterodimerization activity; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0070851 growth factor receptor binding; GO:0035615 clathrin adaptor activity; GO:0043325 phosphatidylinositol-3,4-bisphosphate binding; GO:0035254 glutamate receptor binding; GO:0032266 phosphatidylinositol-3-phosphate binding; GO:0005200 structural constituent of cytoskeleton; GO:0005154 epidermal growth factor receptor binding; GO:0042803 protein homodimerization activity; GO:0005543 phospholipid binding; GO:0003779 actin binding; GO:0060090 binding, bridging; GO:0005198 structural molecule activity; GO:0032403 protein complex binding; ","K04559","HIP1; huntingtin interacting protein 1","hsa05016 Huntington's disease - Homo sapiens (human); ","IPR002558; IPR032422; IPR013809; IPR011417; IPR008942; ","\"I/LWEQ domain; Huntingtin-interacting protein 1, clathrin-binding domain; ENTH  domain; AP180 N-terminal homology (ANTH) domain; ENTH/VHS; \"\r"]
["O00299","Chloride intracellular channel protein 1 OS=Homo sapiens OX=9606 GN=CLIC1","CLIC1",26.922,269.38,68.5,12,30,12,1.001,0.941,0.926,1.051,1.041,1.067,1.101,0.0173,"cytoplasm\r","GO:0044700 single organism signaling; GO:0098661 inorganic anion transmembrane transport; GO:0065008 regulation of biological quality; GO:0007596 blood coagulation; GO:0044699 single-organism process; GO:0051234 establishment of localization; GO:0009611 response to wounding; GO:0022610 biological adhesion; GO:0016337 single organismal cell-cell adhesion; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0007155 cell adhesion; GO:0051726 regulation of cell cycle; GO:0045667 regulation of osteoblast differentiation; GO:0051716 cellular response to stimulus; GO:0030168 platelet activation; GO:0098609 cell-cell adhesion; GO:0044763 single-organism cellular process; GO:0043269 regulation of ion transport; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0042391 regulation of membrane potential; GO:0006810 transport; GO:0034762 regulation of transmembrane transport; GO:0050789 regulation of biological process; GO:0045669 positive regulation of osteoblast differentiation; GO:0098602 single organism cell adhesion; GO:0050817 coagulation; GO:0051094 positive regulation of developmental process; GO:0070527 platelet aggregation; GO:0015698 inorganic anion transport; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0034220 ion transmembrane transport; GO:0045778 positive regulation of ossification; GO:0006821 chloride transport; GO:0050896 response to stimulus; GO:0034109 homotypic cell-cell adhesion; GO:0098656 anion transmembrane transport; GO:0051239 regulation of multicellular organismal process; GO:0045597 positive regulation of cell differentiation; GO:0007599 hemostasis; GO:1902476 chloride transmembrane transport; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0050878 regulation of body fluid levels; GO:0006950 response to stress; GO:0098660 inorganic ion transmembrane transport; GO:0051049 regulation of transport; GO:0048518 positive regulation of biological process; GO:0006820 anion transport; GO:0055085 transmembrane transport; GO:0034765 regulation of ion transmembrane transport; GO:0042060 wound healing; GO:0006811 ion transport; GO:0030278 regulation of ossification; GO:0001775 cell activation; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0051881 regulation of mitochondrial membrane potential; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0098862 cluster of actin-based cell projections; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005903 brush border; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0031965 nuclear membrane; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0034702 ion channel complex; GO:1990351 transporter complex; GO:0043227 membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005635 nuclear envelope; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0012505 endomembrane system; GO:1902495 transmembrane transporter complex; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0072562 blood microparticle; GO:0005634 nucleus; GO:0034707 chloride channel complex; GO:0031975 envelope; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0015075 ion transmembrane transporter activity; GO:0022803 passive transmembrane transporter activity; GO:0005253 anion channel activity; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0005254 chloride channel activity; GO:0015267 channel activity; GO:0015103 inorganic anion transmembrane transporter activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0015108 chloride transmembrane transporter activity; GO:0050839 cell adhesion molecule binding; GO:0005244 voltage-gated ion channel activity; GO:0022838 substrate-specific channel activity; GO:0005488 binding; GO:0045296 cadherin binding; GO:0022836 gated channel activity; GO:0005216 ion channel activity; GO:0022832 voltage-gated channel activity; GO:0008509 anion transmembrane transporter activity; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; ","K05021",null,null,"IPR010987; IPR004045; IPR012336; ","\"Glutathione S-transferase, C-terminal-like; Glutathione S-transferase, N-terminal; Thioredoxin-like fold; \"\r"]
["O00303","Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F","EIF3F",37.563,53.049,25.5,7,18,7,0.899,0.885,0.886,1.095,1.148,1.147,1.27,1.35E-4,"mitochondria\r","GO:0070646 protein modification by small protein removal; GO:0075522 IRES-dependent viral translational initiation; GO:0006518 peptide metabolic process; GO:0019081 viral translation; GO:0019058 viral life cycle; GO:0044267 cellular protein metabolic process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0016579 protein deubiquitination; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0002181 cytoplasmic translation; GO:0016032 viral process; GO:0006413 translational initiation; GO:0019080 viral gene expression; GO:0002190 cap-independent translational initiation; GO:0006508 proteolysis; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006412 translation; GO:0009059 macromolecule biosynthetic process; GO:0044419 interspecies interaction between organisms; GO:0009987 cellular process; GO:0002183 cytoplasmic translational initiation; GO:0002192 IRES-dependent translational initiation; GO:0043043 peptide biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0070647 protein modification by small protein conjugation or removal; GO:0043603 cellular amide metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0051704 multi-organism process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0043234 protein complex; GO:0005623 cell; GO:0044444 cytoplasmic part; GO:0005852 eukaryotic translation initiation factor 3 complex; ","GO:0003723 RNA binding; GO:0004843 thiol-dependent ubiquitin-specific protease activity; GO:0008233 peptidase activity; GO:0003743 translation initiation factor activity; GO:0019783 ubiquitin-like protein-specific protease activity; GO:0005515 protein binding; GO:0008234 cysteine-type peptidase activity; GO:0016787 hydrolase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0008135 translation factor activity, RNA binding; GO:0036459 thiol-dependent ubiquitinyl hydrolase activity; GO:0003824 catalytic activity; GO:0031369 translation initiation factor binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0101005 ubiquitinyl hydrolase activity; ","K03249","EIF3F; translation initiation factor 3 subunit F","hsa03013 RNA transport - Homo sapiens (human); ","IPR000555; IPR024969; ","\"JAB1/MPN/MOV34 metalloenzyme domain; Rpn11/EIF3F, C-terminal; \"\r"]
["O00308","NEDD4-like E3 ubiquitin-protein ligase WWP2 OS=Homo sapiens OX=9606 GN=WWP2","WWP2",98.911,2.9544,2.2,2,2,2,0.971,1.05,0.925,1.069,1.017,0.979,1.04,0.42,"mitochondria\r","GO:0044409 entry into host; GO:0065008 regulation of biological quality; GO:0097659 nucleic acid-templated transcription; GO:0009891 positive regulation of biosynthetic process; GO:0051865 protein autoubiquitination; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0032879 regulation of localization; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0046718 viral entry into host cell; GO:0051051 negative regulation of transport; GO:0018130 heterocycle biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0043269 regulation of ion transport; GO:0000122 negative regulation of transcription from RNA polymerase II promoter; GO:0032774 RNA biosynthetic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0031323 regulation of cellular metabolic process; GO:0051704 multi-organism process; GO:0034762 regulation of transmembrane transport; GO:1901575 organic substance catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0030163 protein catabolic process; GO:0051090 regulation of sequence-specific DNA binding transcription factor activity; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051223 regulation of protein transport; GO:0006464 cellular protein modification process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0032412 regulation of ion transmembrane transporter activity; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0051806 entry into cell of other organism involved in symbiotic interaction; GO:0044267 cellular protein metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0000209 protein polyubiquitination; GO:0045892 negative regulation of transcription, DNA-templated; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0044248 cellular catabolic process; GO:0010959 regulation of metal ion transport; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0032880 regulation of protein localization; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:1904062 regulation of cation transmembrane transport; GO:0032409 regulation of transporter activity; GO:0051254 positive regulation of RNA metabolic process; GO:0016567 protein ubiquitination; GO:0051224 negative regulation of protein transport; GO:1901379 regulation of potassium ion transmembrane transport; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0009890 negative regulation of biosynthetic process; GO:0032446 protein modification by small protein conjugation; GO:0031325 positive regulation of cellular metabolic process; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0043412 macromolecule modification; GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0051253 negative regulation of RNA metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0043266 regulation of potassium ion transport; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0022898 regulation of transmembrane transporter activity; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0010605 negative regulation of macromolecule metabolic process; GO:0042391 regulation of membrane potential; GO:0016070 RNA metabolic process; GO:0030260 entry into host cell; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0051828 entry into other organism involved in symbiotic interaction; GO:1902679 negative regulation of RNA biosynthetic process; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:1901016 regulation of potassium ion transmembrane transporter activity; GO:0044092 negative regulation of molecular function; GO:0036211 protein modification process; GO:0070534 protein K63-linked ubiquitination; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0070201 regulation of establishment of protein localization; GO:0010498 proteasomal protein catabolic process; GO:0071704 organic substance metabolic process; GO:0016032 viral process; GO:0032410 negative regulation of transporter activity; GO:0034641 cellular nitrogen compound metabolic process; GO:0006508 proteolysis; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0043632 modification-dependent macromolecule catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0019941 modification-dependent protein catabolic process; GO:0051049 regulation of transport; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0051701 interaction with host; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0034765 regulation of ion transmembrane transport; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0006366 transcription from RNA polymerase II promoter; GO:0009057 macromolecule catabolic process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:1904950 negative regulation of establishment of protein localization; GO:0010467 gene expression; GO:0031327 negative regulation of cellular biosynthetic process; GO:0009056 catabolic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:1990234 transferase complex; GO:0005623 cell; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:1902494 catalytic complex; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0000151 ubiquitin ligase complex; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0019787 ubiquitin-like protein transferase activity; GO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding; GO:0005515 protein binding; GO:0061659 ubiquitin-like protein ligase activity; GO:0061630 ubiquitin protein ligase activity; GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0001085 RNA polymerase II transcription factor binding; GO:0004842 ubiquitin-protein transferase activity; GO:0000989 transcription factor activity, transcription factor binding; GO:0098811 transcriptional repressor activity, RNA polymerase II activating transcription factor binding; GO:0000988 transcription factor activity, protein binding; GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding; GO:0016740 transferase activity; GO:0008134 transcription factor binding; ","K05630","WWP2; NEDD4-like E3 ubiquitin-protein ligase WWP2 [EC:2.3.2.26]","hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human); ","IPR001202; IPR000569; IPR000008; ","WW domain; HECT domain; C2 domain; \r"]
["O00330","Pyruvate dehydrogenase protein X component, mitochondrial OS=Homo sapiens OX=9606 GN=PDHX","PDHX",54.122,26.953,11.6,5,5,5,1.01,1.046,1.104,1.017,0.991,0.849,0.904,0.171,"mitochondria\r","GO:0051188 cofactor biosynthetic process; GO:0019362 pyridine nucleotide metabolic process; GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0019216 regulation of lipid metabolic process; GO:0072524 pyridine-containing compound metabolic process; GO:0044237 cellular metabolic process; GO:0035384 thioester biosynthetic process; GO:0044272 sulfur compound biosynthetic process; GO:0006796 phosphate-containing compound metabolic process; GO:0006085 acetyl-CoA biosynthetic process; GO:0051196 regulation of coenzyme metabolic process; GO:0008152 metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0009108 coenzyme biosynthetic process; GO:0046487 glyoxylate metabolic process; GO:0006790 sulfur compound metabolic process; GO:0051193 regulation of cofactor metabolic process; GO:0051174 regulation of phosphorus metabolic process; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0071616 acyl-CoA biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006081 cellular aldehyde metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0006732 coenzyme metabolic process; GO:0006084 acetyl-CoA metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0051186 cofactor metabolic process; GO:0010565 regulation of cellular ketone metabolic process; GO:0050789 regulation of biological process; GO:0044710 single-organism metabolic process; GO:0019222 regulation of metabolic process; GO:0006082 organic acid metabolic process; GO:0042762 regulation of sulfur metabolic process; GO:0043436 oxoacid metabolic process; GO:0050794 regulation of cellular process; GO:0006725 cellular aromatic compound metabolic process; GO:0046496 nicotinamide nucleotide metabolic process; GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate; GO:0071704 organic substance metabolic process; GO:0006090 pyruvate metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0050812 regulation of acyl-CoA biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0044711 single-organism biosynthetic process; GO:0035383 thioester metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0006637 acyl-CoA metabolic process; GO:0044249 cellular biosynthetic process; GO:0019217 regulation of fatty acid metabolic process; GO:0006793 phosphorus metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0019637 organophosphate metabolic process; GO:0006086 acetyl-CoA biosynthetic process from pyruvate; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0045254 pyruvate dehydrogenase complex; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:1990204 oxidoreductase complex; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0005515 protein binding; GO:0016746 transferase activity, transferring acyl groups; GO:0003824 catalytic activity; GO:0016740 transferase activity; GO:0005488 binding; ","K13997","PDHX; dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex","hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR004167; IPR001078; IPR011053; IPR000089; IPR023213; ","\"E3-binding domain; 2-oxoacid dehydrogenase acyltransferase, catalytic domain; Single hybrid motif; Biotin/lipoyl attachment; Chloramphenicol acetyltransferase-like domain; \"\r"]
["O00339","Matrilin-2 OS=Homo sapiens OX=9606 GN=MATN2","MATN2",106.84,32.82,7.3,5,5,5,1.145,1.053,1.034,0.873,0.93,0.929,0.845,0.0113,"extracellular\r","GO:0033554 cellular response to stress; GO:0016043 cellular component organization; GO:0016477 cell migration; GO:0044707 single-multicellular organism process; GO:0016358 dendrite development; GO:0051674 localization of cell; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0032989 cellular component morphogenesis; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0050896 response to stimulus; GO:0007411 axon guidance; GO:0048468 cell development; GO:0000904 cell morphogenesis involved in differentiation; GO:0009611 response to wounding; GO:0009605 response to external stimulus; GO:0009653 anatomical structure morphogenesis; GO:0030154 cell differentiation; GO:0032990 cell part morphogenesis; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0007409 axonogenesis; GO:0048858 cell projection morphogenesis; GO:0001764 neuron migration; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0006950 response to stress; GO:0048731 system development; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0048812 neuron projection morphogenesis; GO:0008347 glial cell migration; GO:0031102 neuron projection regeneration; GO:0048870 cell motility; GO:0031175 neuron projection development; GO:0006935 chemotaxis; GO:0032501 multicellular organismal process; GO:0000902 cell morphogenesis; GO:0061564 axon development; GO:0030182 neuron differentiation; GO:0042221 response to chemical; GO:0042063 gliogenesis; GO:0048678 response to axon injury; GO:0097485 neuron projection guidance; GO:0030030 cell projection organization; GO:0044767 single-organism developmental process; GO:0006928 movement of cell or subcellular component; GO:0042330 taxis; GO:0040011 locomotion; GO:0031099 regeneration; GO:0051179 localization; GO:0048856 anatomical structure development; GO:0031104 dendrite regeneration; GO:0071840 cellular component organization or biogenesis; ","GO:0031012 extracellular matrix; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005578 proteinaceous extracellular matrix; GO:0005576 extracellular region; GO:0044420 extracellular matrix component; GO:0005604 basement membrane; ","GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0005509 calcium ion binding; GO:0005488 binding; GO:0043167 ion binding; ",{"$nulls":3},"IPR026823; IPR019466; IPR001881; IPR000742; IPR009030; IPR002035; ","\"Complement Clr-like EGF domain; Matrilin, coiled-coil trimerisation domain; EGF-like calcium-binding domain; EGF-like domain; Growth factor receptor cysteine-rich domain; von Willebrand factor, type A; \"\r"]
["O00391","Sulfhydryl oxidase 1 OS=Homo sapiens OX=9606 GN=QSOX1","QSOX1",82.577,17.307,7.2,4,4,4,0.957,1.013,0.903,1.125,1.018,0.992,1.091,0.162,"Golgi apparatus\r","GO:0050794 regulation of cellular process; GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0045454 cell redox homeostasis; GO:0002576 platelet degranulation; GO:0044699 single-organism process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:0051234 establishment of localization; GO:0042592 homeostatic process; GO:0008152 metabolic process; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0009895 negative regulation of catabolic process; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0002443 leukocyte mediated immunity; GO:0031329 regulation of cellular catabolic process; GO:0055114 oxidation-reduction process; GO:0009894 regulation of catabolic process; GO:0002446 neutrophil mediated immunity; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0019725 cellular homeostasis; GO:0002376 immune system process; GO:0031323 regulation of cellular metabolic process; GO:0043312 neutrophil degranulation; GO:0010506 regulation of autophagy; GO:0009892 negative regulation of metabolic process; GO:0002263 cell activation involved in immune response; GO:0002444 myeloid leukocyte mediated immunity; GO:0016241 regulation of macroautophagy; GO:0002366 leukocyte activation involved in immune response; GO:0006810 transport; GO:0031330 negative regulation of cellular catabolic process; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0050789 regulation of biological process; GO:0044710 single-organism metabolic process; GO:0032940 secretion by cell; GO:0019222 regulation of metabolic process; GO:0001775 cell activation; GO:0010507 negative regulation of autophagy; GO:0043299 leukocyte degranulation; GO:0006955 immune response; GO:0051179 localization; GO:0016242 negative regulation of macroautophagy; GO:0065007 biological regulation; GO:0006887 exocytosis; ","GO:0034774 secretory granule lumen; GO:0016020 membrane; GO:1904724 tertiary granule lumen; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0030173 integral component of Golgi membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0031301 integral component of organelle membrane; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0070820 tertiary granule; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0031228 intrinsic component of Golgi membrane; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0035580 specific granule lumen; GO:0042581 specific granule; GO:0031093 platelet alpha granule lumen; GO:0045171 intercellular bridge; GO:0031091 platelet alpha granule; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0031300 intrinsic component of organelle membrane; GO:0044444 cytoplasmic part; ","GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds; GO:0016853 isomerase activity; GO:0003824 catalytic activity; GO:0016972 thiol oxidase activity; GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor; GO:0016667 oxidoreductase activity, acting on a sulfur group of donors; GO:0016860 intramolecular oxidoreductase activity; GO:0003756 protein disulfide isomerase activity; GO:0016971 flavin-linked sulfhydryl oxidase activity; GO:0016491 oxidoreductase activity; ","K10758",null,null,"IPR017905; IPR013766; IPR012336; ","ERV/ALR sulfhydryl oxidase domain; Thioredoxin domain; Thioredoxin-like fold; \r"]
["O00401","Neural Wiskott-Aldrich syndrome protein OS=Homo sapiens OX=9606 GN=WASL","WASL",54.826,6.1003,7.9,4,5,4,1.007,1.088,1.101,0.942,0.927,0.95,0.882,0.0124,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0060627 regulation of vesicle-mediated transport; GO:0065008 regulation of biological quality; GO:0060491 regulation of cell projection assembly; GO:0007166 cell surface receptor signaling pathway; GO:0097659 nucleic acid-templated transcription; GO:0060997 dendritic spine morphogenesis; GO:0032989 cellular component morphogenesis; GO:0030832 regulation of actin filament length; GO:0044237 cellular metabolic process; GO:0009607 response to biotic stimulus; GO:1903729 regulation of plasma membrane organization; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0030036 actin cytoskeleton organization; GO:0065003 macromolecular complex assembly; GO:0032879 regulation of localization; GO:0032535 regulation of cellular component size; GO:0043170 macromolecule metabolic process; GO:0051493 regulation of cytoskeleton organization; GO:0008104 protein localization; GO:0030050 vesicle transport along actin filament; GO:0044765 single-organism transport; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0000278 mitotic cell cycle; GO:0018130 heterocycle biosynthetic process; GO:0048259 regulation of receptor-mediated endocytosis; GO:0080090 regulation of primary metabolic process; GO:0031346 positive regulation of cell projection organization; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0008154 actin polymerization or depolymerization; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0032774 RNA biosynthetic process; GO:0048812 neuron projection morphogenesis; GO:0031323 regulation of cellular metabolic process; GO:2000146 negative regulation of cell motility; GO:0032501 multicellular organismal process; GO:0051341 regulation of oxidoreductase activity; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0000902 cell morphogenesis; GO:1903506 regulation of nucleic acid-templated transcription; GO:0032768 regulation of monooxygenase activity; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0002682 regulation of immune system process; GO:1902905 positive regulation of supramolecular fiber organization; GO:0051301 cell division; GO:0002685 regulation of leukocyte migration; GO:0097435 supramolecular fiber organization; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:1902903 regulation of supramolecular fiber organization; GO:0050794 regulation of cellular process; GO:0051640 organelle localization; GO:0046907 intracellular transport; GO:0044707 single-multicellular organism process; GO:0097061 dendritic spine organization; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0032956 regulation of actin cytoskeleton organization; GO:2000370 positive regulation of clathrin-dependent endocytosis; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation; GO:1903047 mitotic cell cycle process; GO:0030705 cytoskeleton-dependent intracellular transport; GO:1903525 regulation of membrane tubulation; GO:0009653 anatomical structure morphogenesis; GO:0046483 heterocycle metabolic process; GO:1902578 single-organism localization; GO:0034629 cellular protein complex localization; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0009889 regulation of biosynthetic process; GO:2000145 regulation of cell motility; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902580 single-organism cellular localization; GO:0032880 regulation of protein localization; GO:0007275 multicellular organism development; GO:0038093 Fc receptor signaling pathway; GO:0034613 cellular protein localization; GO:0007010 cytoskeleton organization; GO:0050778 positive regulation of immune response; GO:0006461 protein complex assembly; GO:0009617 response to bacterium; GO:0002253 activation of immune response; GO:0030100 regulation of endocytosis; GO:0051495 positive regulation of cytoskeleton organization; GO:0051270 regulation of cellular component movement; GO:0051125 regulation of actin nucleation; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0002376 immune system process; GO:0030334 regulation of cell migration; GO:0032970 regulation of actin filament-based process; GO:0044238 primary metabolic process; GO:0051656 establishment of organelle localization; GO:1901576 organic substance biosynthetic process; GO:0008064 regulation of actin polymerization or depolymerization; GO:0030182 neuron differentiation; GO:0051491 positive regulation of filopodium assembly; GO:0060996 dendritic spine development; GO:0030336 negative regulation of cell migration; GO:0006996 organelle organization; GO:0006900 membrane budding; GO:0061024 membrane organization; GO:0030029 actin filament-based process; GO:0006928 movement of cell or subcellular component; GO:0000280 nuclear division; GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0051127 positive regulation of actin nucleation; GO:0030048 actin filament-based movement; GO:0030833 regulation of actin filament polymerization; GO:0038094 Fc-gamma receptor signaling pathway; GO:0051129 negative regulation of cellular component organization; GO:0007067 mitotic nuclear division; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation; GO:0009058 biosynthetic process; GO:0006909 phagocytosis; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0040013 negative regulation of locomotion; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0032990 cell part morphogenesis; GO:0048858 cell projection morphogenesis; GO:0032271 regulation of protein polymerization; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0099515 actin filament-based transport; GO:0033036 macromolecule localization; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0032502 developmental process; GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis; GO:0010468 regulation of gene expression; GO:0051650 establishment of vesicle localization; GO:0071822 protein complex subunit organization; GO:0031326 regulation of cellular biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:1902582 single-organism intracellular transport; GO:0051050 positive regulation of transport; GO:0016070 RNA metabolic process; GO:0002683 negative regulation of immune system process; GO:1902589 single-organism organelle organization; GO:0099518 vesicle cytoskeletal trafficking; GO:0050789 regulation of biological process; GO:0043254 regulation of protein complex assembly; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0030030 cell projection organization; GO:0010638 positive regulation of organelle organization; GO:0048813 dendrite morphogenesis; GO:1903526 negative regulation of membrane tubulation; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0002431 Fc receptor mediated stimulatory signaling pathway; GO:0070271 protein complex biogenesis; GO:2000369 regulation of clathrin-dependent endocytosis; GO:0050999 regulation of nitric-oxide synthase activity; GO:0048856 anatomical structure development; GO:0048260 positive regulation of receptor-mediated endocytosis; GO:0031503 protein complex localization; GO:0051271 negative regulation of cellular component movement; GO:0002686 negative regulation of leukocyte migration; GO:0016043 cellular component organization; GO:0016358 dendrite development; GO:0006725 cellular aromatic compound metabolic process; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0045807 positive regulation of endocytosis; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0048285 organelle fission; GO:0051653 spindle localization; GO:0007015 actin filament organization; GO:0031344 regulation of cell projection organization; GO:0044087 regulation of cellular component biogenesis; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0048468 cell development; GO:0071704 organic substance metabolic process; GO:0051489 regulation of filopodium assembly; GO:0000904 cell morphogenesis involved in differentiation; GO:0030154 cell differentiation; GO:0048013 ephrin receptor signaling pathway; GO:0051648 vesicle localization; GO:0002757 immune response-activating signal transduction; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:2000402 negative regulation of lymphocyte migration; GO:0006355 regulation of transcription, DNA-templated; GO:0051049 regulation of transport; GO:0006807 nitrogen compound metabolic process; GO:0016050 vesicle organization; GO:0033043 regulation of organelle organization; GO:0010556 regulation of macromolecule biosynthetic process; GO:0006897 endocytosis; GO:0031175 neuron projection development; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0051641 cellular localization; GO:0070727 cellular macromolecule localization; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:2000401 regulation of lymphocyte migration; GO:0044767 single-organism developmental process; GO:0002684 positive regulation of immune system process; GO:0090066 regulation of anatomical structure size; GO:0010467 gene expression; GO:0051128 regulation of cellular component organization; GO:0022402 cell cycle process; GO:0040012 regulation of locomotion; GO:0044089 positive regulation of cellular component biogenesis; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005938 cell cortex; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0099568 cytoplasmic region; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0030863 cortical cytoskeleton; GO:0030864 cortical actin cytoskeleton; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0030027 lamellipodium; GO:1903561 extracellular vesicle; GO:0030139 endocytic vesicle; GO:0043227 membrane-bounded organelle; GO:0030478 actin cap; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0031252 cell leading edge; GO:0042995 cell projection; GO:0098588 bounding membrane of organelle; GO:0030666 endocytic vesicle membrane; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0012506 vesicle membrane; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0015629 actin cytoskeleton; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0044448 cell cortex part; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0008092 cytoskeletal protein binding; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0030695 GTPase regulator activity; GO:0003779 actin binding; GO:0005515 protein binding; GO:0098772 molecular function regulator; ","K05747","WAS; Wiskott-Aldrich syndrome protein","hsa05100 Bacterial invasion of epithelial cells - Homo sapiens (human); hsa05132 Salmonella infection - Homo sapiens (human); hsa04666 Fc gamma R-mediated phagocytosis - Homo sapiens (human); hsa05231 Choline metabolism in cancer - Homo sapiens (human); hsa04530 Tight junction - Homo sapiens (human); hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa04520 Adherens junction - Homo sapiens (human); hsa04144 Endocytosis - Homo sapiens (human); hsa05131 Shigellosis - Homo sapiens (human); hsa04062 Chemokine signaling pathway - Homo sapiens (human); ","IPR033927; IPR003124; IPR011993; IPR000095; IPR011026; IPR000697; ","\"WASP family, EVH1 domain; WH2 domain; PH domain-like; CRIB domain; Wiscott-Aldrich syndrome protein, C-terminal; WH1/EVH1 domain; \"\r"]
["O00410","Importin-5 OS=Homo sapiens OX=9606 GN=IPO5","IPO5",123.63,208.24,26.5,24,37,22,0.918,0.934,0.951,1.07,1.023,1.065,1.127,0.00244,"cytoplasm\r","GO:0001101 response to acid chemical; GO:0006607 NLS-bearing protein import into nucleus; GO:0072594 establishment of protein localization to organelle; GO:1903533 regulation of protein targeting; GO:0017038 protein import; GO:0044699 single-organism process; GO:0051169 nuclear transport; GO:0044764 multi-organism cellular process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0042306 regulation of protein import into nucleus; GO:0051649 establishment of localization in cell; GO:0032879 regulation of localization; GO:0046824 positive regulation of nucleocytoplasmic transport; GO:0009719 response to endogenous stimulus; GO:0033365 protein localization to organelle; GO:0044419 interspecies interaction between organisms; GO:0006606 protein import into nucleus; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0034260 negative regulation of GTPase activity; GO:0070887 cellular response to chemical stimulus; GO:0044765 single-organism transport; GO:0043200 response to amino acid; GO:0051716 cellular response to stimulus; GO:0032386 regulation of intracellular transport; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0006610 ribosomal protein import into nucleus; GO:0043086 negative regulation of catalytic activity; GO:0051704 multi-organism process; GO:1902582 single-organism intracellular transport; GO:0051050 positive regulation of transport; GO:0071417 cellular response to organonitrogen compound; GO:0006810 transport; GO:0010243 response to organonitrogen compound; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0051336 regulation of hydrolase activity; GO:1901699 cellular response to nitrogen compound; GO:0050790 regulation of catalytic activity; GO:0071230 cellular response to amino acid stimulus; GO:1900180 regulation of protein localization to nucleus; GO:1901698 response to nitrogen compound; GO:0043087 regulation of GTPase activity; GO:0065009 regulation of molecular function; GO:0051223 regulation of protein transport; GO:0044092 negative regulation of molecular function; GO:0006913 nucleocytoplasmic transport; GO:0051222 positive regulation of protein transport; GO:0042307 positive regulation of protein import into nucleus; GO:0046907 intracellular transport; GO:0090316 positive regulation of intracellular protein transport; GO:0000060 protein import into nucleus, translocation; GO:1903829 positive regulation of cellular protein localization; GO:1902593 single-organism nuclear import; GO:0071310 cellular response to organic substance; GO:1901700 response to oxygen-containing compound; GO:1904589 regulation of protein import; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0070201 regulation of establishment of protein localization; GO:0051346 negative regulation of hydrolase activity; GO:0060341 regulation of cellular localization; GO:1902578 single-organism localization; GO:0071229 cellular response to acid chemical; GO:0016032 viral process; GO:0006886 intracellular protein transport; GO:0044744 protein targeting to nucleus; GO:1902580 single-organism cellular localization; GO:0032880 regulation of protein localization; GO:0034613 cellular protein localization; GO:0033157 regulation of intracellular protein transport; GO:0009987 cellular process; GO:0051049 regulation of transport; GO:0032388 positive regulation of intracellular transport; GO:0071702 organic substance transport; GO:0010033 response to organic substance; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:1900182 positive regulation of protein localization to nucleus; GO:0070727 cellular macromolecule localization; GO:1901701 cellular response to oxygen-containing compound; GO:0046822 regulation of nucleocytoplasmic transport; GO:1904951 positive regulation of establishment of protein localization; GO:0051170 nuclear import; GO:0071495 cellular response to endogenous stimulus; GO:0051179 localization; GO:0034504 protein localization to nucleus; GO:1903827 regulation of cellular protein localization; GO:1904591 positive regulation of protein import; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005643 nuclear pore; GO:0031090 organelle membrane; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005635 nuclear envelope; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005730 nucleolus; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031965 nuclear membrane; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0031975 envelope; GO:0034399 nuclear periphery; GO:0043227 membrane-bounded organelle; GO:0043234 protein complex; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0031267 small GTPase binding; GO:0003723 RNA binding; GO:0008565 protein transporter activity; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0030695 GTPase regulator activity; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0033218 amide binding; GO:0005095 GTPase inhibitor activity; GO:0098772 molecular function regulator; GO:0004857 enzyme inhibitor activity; GO:0005048 signal sequence binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0030234 enzyme regulator activity; GO:0017016 Ras GTPase binding; GO:0042277 peptide binding; GO:0005488 binding; GO:0008139 nuclear localization sequence binding; GO:0003676 nucleic acid binding; GO:0008536 Ran GTPase binding; GO:0051020 GTPase binding; GO:0019899 enzyme binding; GO:0005215 transporter activity; ","K20222",null,null,"IPR001494; IPR034085; IPR011989; IPR016024; ","\"Importin-beta, N-terminal domain; TOG domain; Armadillo-like helical; Armadillo-type fold; \"\r"]
["O00418","Eukaryotic elongation factor 2 kinase OS=Homo sapiens OX=9606 GN=EEF2K","EEF2K",82.143,9.2325,7.6,5,5,5,1.045,0.924,0.951,1.099,0.982,1.007,1.058,0.328,"cyto_nucl\r","GO:0060627 regulation of vesicle-mediated transport; GO:0010941 regulation of cell death; GO:0065008 regulation of biological quality; GO:0006518 peptide metabolic process; GO:0051965 positive regulation of synapse assembly; GO:0046683 response to organophosphorus; GO:0044237 cellular metabolic process; GO:0050807 regulation of synapse organization; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0009719 response to endogenous stimulus; GO:0070848 response to growth factor; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:1901652 response to peptide; GO:0007399 nervous system development; GO:0042325 regulation of phosphorylation; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0031346 positive regulation of cell projection organization; GO:0044763 single-organism cellular process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0010243 response to organonitrogen compound; GO:0051591 response to cAMP; GO:0032869 cellular response to insulin stimulus; GO:0044260 cellular macromolecule metabolic process; GO:1901698 response to nitrogen compound; GO:0060999 positive regulation of dendritic spine development; GO:0006464 cellular protein modification process; GO:0060548 negative regulation of cell death; GO:0051094 positive regulation of developmental process; GO:0010975 regulation of neuron projection development; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0033554 cellular response to stress; GO:0016310 phosphorylation; GO:0034059 response to anoxia; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0043067 regulation of programmed cell death; GO:1901700 response to oxygen-containing compound; GO:0044267 cellular protein metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0045597 positive regulation of cell differentiation; GO:0048814 regulation of dendrite morphogenesis; GO:0051239 regulation of multicellular organismal process; GO:1900006 positive regulation of dendrite development; GO:0014074 response to purine-containing compound; GO:0070482 response to oxygen levels; GO:0007275 multicellular organism development; GO:1990089 response to nerve growth factor; GO:0030100 regulation of endocytosis; GO:0006950 response to stress; GO:0006414 translational elongation; GO:0048731 system development; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0071407 cellular response to organic cyclic compound; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0010976 positive regulation of neuron projection development; GO:0006793 phosphorus metabolic process; GO:0050769 positive regulation of neurogenesis; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:0036293 response to decreased oxygen levels; GO:0043412 macromolecule modification; GO:0071248 cellular response to metal ion; GO:0050793 regulation of developmental process; GO:1901564 organonitrogen compound metabolic process; GO:0045666 positive regulation of neuron differentiation; GO:0048869 cellular developmental process; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0071363 cellular response to growth factor stimulus; GO:0006796 phosphate-containing compound metabolic process; GO:0051130 positive regulation of cellular component organization; GO:0002931 response to ischemia; GO:1901653 cellular response to peptide; GO:0071454 cellular response to anoxia; GO:0046777 protein autophosphorylation; GO:0010035 response to inorganic substance; GO:0010720 positive regulation of cell development; GO:0006412 translation; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:1990637 response to prolactin; GO:0060998 regulation of dendritic spine development; GO:0043043 peptide biosynthetic process; GO:0051963 regulation of synapse assembly; GO:0051962 positive regulation of nervous system development; GO:0048522 positive regulation of cellular process; GO:0043603 cellular amide metabolic process; GO:1990416 cellular response to brain-derived neurotrophic factor stimulus; GO:0010038 response to metal ion; GO:0051050 positive regulation of transport; GO:0071417 cellular response to organonitrogen compound; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0032868 response to insulin; GO:0043434 response to peptide hormone; GO:0045664 regulation of neuron differentiation; GO:1901699 cellular response to nitrogen compound; GO:0032870 cellular response to hormone stimulus; GO:0071241 cellular response to inorganic substance; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0061001 regulation of dendritic spine morphogenesis; GO:0043069 negative regulation of programmed cell death; GO:0045807 positive regulation of endocytosis; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0010770 positive regulation of cell morphogenesis involved in differentiation; GO:0031344 regulation of cell projection organization; GO:0044087 regulation of cellular component biogenesis; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0006468 protein phosphorylation; GO:0043066 negative regulation of apoptotic process; GO:0071375 cellular response to peptide hormone stimulus; GO:0051592 response to calcium ion; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0071453 cellular response to oxygen levels; GO:0009987 cellular process; GO:0061003 positive regulation of dendritic spine morphogenesis; GO:0045595 regulation of cell differentiation; GO:0050803 regulation of synapse structure or activity; GO:0071320 cellular response to cAMP; GO:0051049 regulation of transport; GO:1990090 cellular response to nerve growth factor stimulus; GO:0001932 regulation of protein phosphorylation; GO:0006807 nitrogen compound metabolic process; GO:0071277 cellular response to calcium ion; GO:0031952 regulation of protein autophosphorylation; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0050775 positive regulation of dendrite morphogenesis; GO:1901701 cellular response to oxygen-containing compound; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044767 single-organism developmental process; GO:0071495 cellular response to endogenous stimulus; GO:0051246 regulation of protein metabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0050773 regulation of dendrite development; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0051128 regulation of cellular component organization; GO:0009725 response to hormone; GO:0022604 regulation of cell morphogenesis; GO:0044089 positive regulation of cellular component biogenesis; GO:0042981 regulation of apoptotic process; GO:0036294 cellular response to decreased oxygen levels; GO:0050767 regulation of neurogenesis; GO:0065007 biological regulation; ","GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0032279 asymmetric synapse; GO:0045202 synapse; GO:0043226 organelle; GO:0098794 postsynapse; GO:0005622 intracellular; GO:0044464 cell part; GO:0014069 postsynaptic density; GO:0099572 postsynaptic specialization; GO:0098984 neuron to neuron synapse; GO:0044444 cytoplasmic part; GO:0044456 synapse part; ","GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0005515 protein binding; GO:0004672 protein kinase activity; GO:0004683 calmodulin-dependent protein kinase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0016301 kinase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0004686 elongation factor-2 kinase activity; GO:0003723 RNA binding; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0005516 calmodulin binding; GO:0008135 translation factor activity, RNA binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003676 nucleic acid binding; GO:0046872 metal ion binding; GO:0004674 protein serine/threonine kinase activity; GO:0032555 purine ribonucleotide binding; GO:0005509 calcium ion binding; GO:0001883 purine nucleoside binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0036094 small molecule binding; ","K08292","EEF2K; elongation factor 2 kinase [EC:2.7.11.20]","hsa04921 Oxytocin signaling pathway - Homo sapiens (human); hsa04152 AMPK signaling pathway - Homo sapiens (human); ","IPR011990; IPR004166; IPR011009; ","Tetratricopeptide-like helical domain; MHCK/EF2 kinase; Protein kinase-like domain; \r"]
["O00422","Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18","SAP18",17.561,1.9325,5.9,1,1,1,1.029,0.987,0.973,0.993,1.129,0.897,1.01,0.936,"nucleus\r","GO:0010941 regulation of cell death; GO:0000381 regulation of alternative mRNA splicing, via spliceosome; GO:0097659 nucleic acid-templated transcription; GO:0050686 negative regulation of mRNA processing; GO:0009058 biosynthetic process; GO:0051253 negative regulation of RNA metabolic process; GO:1903312 negative regulation of mRNA metabolic process; GO:0044237 cellular metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0098732 macromolecule deacylation; GO:0048024 regulation of mRNA splicing, via spliceosome; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0006476 protein deacetylation; GO:0006396 RNA processing; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0032774 RNA biosynthetic process; GO:0050684 regulation of mRNA processing; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0010942 positive regulation of cell death; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0035601 protein deacylation; GO:0006351 transcription, DNA-templated; GO:1902679 negative regulation of RNA biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0033119 negative regulation of RNA splicing; GO:0019222 regulation of metabolic process; GO:0006464 cellular protein modification process; GO:0006325 chromatin organization; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0036211 protein modification process; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0043068 positive regulation of programmed cell death; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0016570 histone modification; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0043067 regulation of programmed cell death; GO:0043065 positive regulation of apoptotic process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0048523 negative regulation of cellular process; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0016569 covalent chromatin modification; GO:0009059 macromolecule biosynthetic process; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0016575 histone deacetylation; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0043484 regulation of RNA splicing; GO:0009890 negative regulation of biosynthetic process; GO:1903311 regulation of mRNA metabolic process; GO:0051276 chromosome organization; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0006996 organelle organization; GO:0010467 gene expression; GO:0031327 negative regulation of cellular biosynthetic process; GO:0043412 macromolecule modification; GO:0048025 negative regulation of mRNA splicing, via spliceosome; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0016604 nuclear body; GO:0005623 cell; GO:0000118 histone deacetylase complex; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:1902494 catalytic complex; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0061574 ASAP complex; GO:0005622 intracellular; GO:0044464 cell part; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0003723 RNA binding; GO:0003714 transcription corepressor activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0003712 transcription cofactor activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0004407 histone deacetylase activity; GO:0033558 protein deacetylase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0019213 deacetylase activity; GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; GO:0000988 transcription factor activity, protein binding; GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; ","K14324","SAP18; histone deacetylase complex subunit SAP18","hsa03015 mRNA surveillance pathway - Homo sapiens (human); hsa03013 RNA transport - Homo sapiens (human); "]
["O00429","Dynamin-1-like protein OS=Homo sapiens OX=9606 GN=DNM1L","DNM1L",81.876,39.478,14.8,11,15,11,0.972,0.997,1.002,0.961,1.08,0.98,1.017,0.7,"cytoplasm\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0010941 regulation of cell death; GO:0032989 cellular component morphogenesis; GO:0032459 regulation of protein oligomerization; GO:0010821 regulation of mitochondrion organization; GO:0009605 response to external stimulus; GO:1905395 response to flavonoid; GO:1990910 response to hypobaric hypoxia; GO:0051240 positive regulation of multicellular organismal process; GO:0065003 macromolecular complex assembly; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0033365 protein localization to organelle; GO:0008104 protein localization; GO:0090140 regulation of mitochondrial fission; GO:0016559 peroxisome fission; GO:0007399 nervous system development; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0048699 generation of neurons; GO:0031346 positive regulation of cell projection organization; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0061025 membrane fusion; GO:0031323 regulation of cellular metabolic process; GO:0010506 regulation of autophagy; GO:0032501 multicellular organismal process; GO:0071396 cellular response to lipid; GO:0006810 transport; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0050714 positive regulation of protein secretion; GO:0060999 positive regulation of dendritic spine development; GO:0097194 execution phase of apoptosis; GO:2001244 positive regulation of intrinsic apoptotic signaling pathway; GO:0051223 regulation of protein transport; GO:0003015 heart process; GO:0003013 circulatory system process; GO:0051094 positive regulation of developmental process; GO:0006140 regulation of nucleotide metabolic process; GO:0010975 regulation of neuron projection development; GO:0043068 positive regulation of programmed cell death; GO:0051047 positive regulation of secretion; GO:0051640 organelle localization; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0097190 apoptotic signaling pathway; GO:0051260 protein homooligomerization; GO:0009628 response to abiotic stimulus; GO:1901700 response to oxygen-containing compound; GO:0043067 regulation of programmed cell death; GO:0090148 membrane fission; GO:0070584 mitochondrion morphogenesis; GO:0045597 positive regulation of cell differentiation; GO:0048814 regulation of dendrite morphogenesis; GO:0051239 regulation of multicellular organismal process; GO:0051259 protein oligomerization; GO:0007031 peroxisome organization; GO:1900006 positive regulation of dendrite development; GO:0009653 anatomical structure morphogenesis; GO:0051646 mitochondrion localization; GO:0051345 positive regulation of hydrolase activity; GO:0003374 dynamin family protein polymerization involved in mitochondrial fission; GO:0070482 response to oxygen levels; GO:0051171 regulation of nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0032880 regulation of protein localization; GO:0034613 cellular protein localization; GO:0009966 regulation of signal transduction; GO:0043653 mitochondrial fragmentation involved in apoptotic process; GO:0006461 protein complex assembly; GO:1902531 regulation of intracellular signal transduction; GO:0006950 response to stress; GO:0043547 positive regulation of GTPase activity; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0051960 regulation of nervous system development; GO:0060284 regulation of cell development; GO:1900063 regulation of peroxisome organization; GO:0071496 cellular response to external stimulus; GO:0071407 cellular response to organic cyclic compound; GO:0097300 programmed necrotic cell death; GO:0010033 response to organic substance; GO:0031668 cellular response to extracellular stimulus; GO:1904578 response to thapsigargin; GO:0090649 response to oxygen-glucose deprivation; GO:1904951 positive regulation of establishment of protein localization; GO:0010976 positive regulation of neuron projection development; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0050769 positive regulation of neurogenesis; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:0012501 programmed cell death; GO:0036293 response to decreased oxygen levels; GO:0070266 necroptotic process; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:0050793 regulation of developmental process; GO:0048312 intracellular distribution of mitochondria; GO:0045666 positive regulation of neuron differentiation; GO:0090199 regulation of release of cytochrome c from mitochondria; GO:0023051 regulation of signaling; GO:0048869 cellular developmental process; GO:1902533 positive regulation of intracellular signal transduction; GO:0022008 neurogenesis; GO:0051046 regulation of secretion; GO:0044699 single-organism process; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:2001233 regulation of apoptotic signaling pathway; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0032990 cell part morphogenesis; GO:0051262 protein tetramerization; GO:0007005 mitochondrion organization; GO:0006915 apoptotic process; GO:0033036 macromolecule localization; GO:0010720 positive regulation of cell development; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0071822 protein complex subunit organization; GO:0060998 regulation of dendritic spine development; GO:0070265 necrotic cell death; GO:0051962 positive regulation of nervous system development; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:1903530 regulation of secretion by cell; GO:0051050 positive regulation of transport; GO:0010942 positive regulation of cell death; GO:0090141 positive regulation of mitochondrial fission; GO:1902589 single-organism organelle organization; GO:0043254 regulation of protein complex assembly; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0045664 regulation of neuron differentiation; GO:0010638 positive regulation of organelle organization; GO:1903532 positive regulation of secretion by cell; GO:0051258 protein polymerization; GO:0043087 regulation of GTPase activity; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0090200 positive regulation of release of cytochrome c from mitochondria; GO:0070271 protein complex biogenesis; GO:0048856 anatomical structure development; GO:0051222 positive regulation of protein transport; GO:2000026 regulation of multicellular organismal development; GO:0016043 cellular component organization; GO:0061001 regulation of dendritic spine morphogenesis; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0071310 cellular response to organic substance; GO:0048285 organelle fission; GO:0009118 regulation of nucleoside metabolic process; GO:0010770 positive regulation of cell morphogenesis involved in differentiation; GO:0043065 positive regulation of apoptotic process; GO:0031344 regulation of cell projection organization; GO:0044087 regulation of cellular component biogenesis; GO:0050896 response to stimulus; GO:0070201 regulation of establishment of protein localization; GO:0031669 cellular response to nutrient levels; GO:1904579 cellular response to thapsigargin; GO:0033993 response to lipid; GO:0090650 cellular response to oxygen-glucose deprivation; GO:0009991 response to extracellular stimulus; GO:0030154 cell differentiation; GO:0051289 protein homotetramerization; GO:0048311 mitochondrion distribution; GO:0003373 dynamin family protein polymerization involved in membrane fission; GO:0023056 positive regulation of signaling; GO:0001666 response to hypoxia; GO:0008015 blood circulation; GO:2001235 positive regulation of apoptotic signaling pathway; GO:0010647 positive regulation of cell communication; GO:0060047 heart contraction; GO:0050708 regulation of protein secretion; GO:0071453 cellular response to oxygen levels; GO:0009987 cellular process; GO:0061003 positive regulation of dendritic spine morphogenesis; GO:0045595 regulation of cell differentiation; GO:0043623 cellular protein complex assembly; GO:1903578 regulation of ATP metabolic process; GO:0034622 cellular macromolecular complex assembly; GO:0003008 system process; GO:0008637 apoptotic mitochondrial changes; GO:0051049 regulation of transport; GO:0033043 regulation of organelle organization; GO:0044802 single-organism membrane organization; GO:0070585 protein localization to mitochondrion; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0001836 release of cytochrome c from mitochondria; GO:0000266 mitochondrial fission; GO:0051641 cellular localization; GO:0043085 positive regulation of catalytic activity; GO:0010822 positive regulation of mitochondrion organization; GO:0043933 macromolecular complex subunit organization; GO:1900542 regulation of purine nucleotide metabolic process; GO:0050775 positive regulation of dendrite morphogenesis; GO:0070727 cellular macromolecule localization; GO:1901701 cellular response to oxygen-containing compound; GO:1903146 regulation of mitophagy; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:2001242 regulation of intrinsic apoptotic signaling pathway; GO:0050773 regulation of dendrite development; GO:0051128 regulation of cellular component organization; GO:0009967 positive regulation of signal transduction; GO:0031667 response to nutrient levels; GO:0090149 mitochondrial membrane fission; GO:0022604 regulation of cell morphogenesis; GO:0042981 regulation of apoptotic process; GO:0036294 cellular response to decreased oxygen levels; GO:0050767 regulation of neurogenesis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0019867 outer membrane; GO:0098862 cluster of actin-based cell projections; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070382 exocytic vesicle; GO:0008021 synaptic vesicle; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0098589 membrane region; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0005789 endoplasmic reticulum membrane; GO:0099513 polymeric cytoskeletal fiber; GO:0044430 cytoskeletal part; GO:0031967 organelle envelope; GO:0012506 vesicle membrane; GO:0030672 synaptic vesicle membrane; GO:0005739 mitochondrion; GO:0099081 supramolecular polymer; GO:0043231 intracellular membrane-bounded organelle; GO:0031975 envelope; GO:0005905 clathrin-coated pit; GO:0043234 protein complex; GO:0030133 transport vesicle; GO:0031966 mitochondrial membrane; GO:0030658 transport vesicle membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0005874 microtubule; GO:0005903 brush border; GO:0031410 cytoplasmic vesicle; GO:0030054 cell junction; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0099512 supramolecular fiber; GO:0099501 exocytic vesicle membrane; GO:0005740 mitochondrial envelope; GO:0005856 cytoskeleton; GO:0015630 microtubule cytoskeleton; GO:0044464 cell part; GO:0044425 membrane part; GO:0098793 presynapse; GO:0098805 whole membrane; GO:0042579 microbody; GO:0044431 Golgi apparatus part; GO:0048471 perinuclear region of cytoplasm; GO:0031968 organelle outer membrane; GO:0044456 synapse part; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0044429 mitochondrial part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005777 peroxisome; GO:0005741 mitochondrial outer membrane; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0045202 synapse; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0044432 endoplasmic reticulum part; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0031625 ubiquitin protein ligase binding; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0030695 GTPase regulator activity; GO:0046983 protein dimerization activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0017137 Rab GTPase binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0008092 cytoskeletal protein binding; GO:0042802 identical protein binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0017016 Ras GTPase binding; GO:0003824 catalytic activity; GO:0008017 microtubule binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0003924 GTPase activity; GO:0008289 lipid binding; GO:0043168 anion binding; GO:0019001 guanyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0051020 GTPase binding; GO:0005525 GTP binding; GO:0008047 enzyme activator activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0031267 small GTPase binding; GO:0030742 GTP-dependent protein binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0015631 tubulin binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0030234 enzyme regulator activity; GO:0042803 protein homodimerization activity; GO:0032555 purine ribonucleotide binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0019899 enzyme binding; GO:0036094 small molecule binding; GO:0005096 GTPase activator activity; ","K17065","DNM1L; dynamin 1-like protein [EC:3.6.5.5]","hsa04668 TNF signaling pathway - Homo sapiens (human); hsa04217 Necroptosis - Homo sapiens (human); hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human); ","IPR030381; IPR003130; IPR001401; IPR027417; IPR020850; IPR000375; ","\"Dynamin-type guanine nucleotide-binding (G) domain; Dynamin GTPase effector; Dynamin, GTPase domain; P-loop containing nucleoside triphosphate hydrolase; GTPase effector domain; Dynamin central domain; \"\r"]
["O00461","Golgi integral membrane protein 4 OS=Homo sapiens OX=9606 GN=GOLIM4","GOLIM4",81.879,12.124,6.3,4,4,4,1.067,1.065,1.108,0.939,0.856,0.983,0.857,0.022,"extracellular\r","GO:0006810 transport; GO:0051179 localization; GO:0051234 establishment of localization; ","GO:0016020 membrane; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0005801 cis-Golgi network; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0098791 Golgi subcompartment; GO:0044431 Golgi apparatus part; GO:0005768 endosome; GO:0030139 endocytic vesicle; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0010008 endosome membrane; GO:0098588 bounding membrane of organelle; GO:0032580 Golgi cisterna membrane; GO:0044446 intracellular organelle part; GO:0005796 Golgi lumen; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0005795 Golgi stack; GO:0016021 integral component of membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0030133 transport vesicle; GO:0005794 Golgi apparatus; GO:0031985 Golgi cisterna; GO:0044444 cytoplasmic part; GO:0031984 organelle subcompartment; "]
["O00468","Agrin OS=Homo sapiens OX=9606 GN=AGRN","AGRN",217.23,47.413,6.1,10,11,10,1.107,1.014,1.07,0.927,0.858,0.986,0.868,0.0407,"extracellular\r","GO:0044700 single organism signaling; GO:0021700 developmental maturation; GO:0065008 regulation of biological quality; GO:0060491 regulation of cell projection assembly; GO:1904398 positive regulation of neuromuscular junction development; GO:0051965 positive regulation of synapse assembly; GO:0009891 positive regulation of biosynthetic process; GO:0044255 cellular lipid metabolic process; GO:0045161 neuronal ion channel clustering; GO:0008582 regulation of synaptic growth at neuromuscular junction; GO:0044237 cellular metabolic process; GO:0050807 regulation of synapse organization; GO:0045927 positive regulation of growth; GO:0030203 glycosaminoglycan metabolic process; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0051240 positive regulation of multicellular organismal process; GO:0044093 positive regulation of molecular function; GO:0043170 macromolecule metabolic process; GO:0008104 protein localization; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0072657 protein localization to membrane; GO:0080090 regulation of primary metabolic process; GO:0060359 response to ammonium ion; GO:0048699 generation of neurons; GO:0031346 positive regulation of cell projection organization; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044763 single-organism cellular process; GO:0031323 regulation of cellular metabolic process; GO:0071242 cellular response to ammonium ion; GO:0032501 multicellular organismal process; GO:0006027 glycosaminoglycan catabolic process; GO:0043113 receptor clustering; GO:1901575 organic substance catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:1901698 response to nitrogen compound; GO:0010604 positive regulation of macromolecule metabolic process; GO:0016101 diterpenoid metabolic process; GO:0051094 positive regulation of developmental process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:1905144 response to acetylcholine; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:1901700 response to oxygen-containing compound; GO:0051239 regulation of multicellular organismal process; GO:0051345 positive regulation of hydrolase activity; GO:0043062 extracellular structure organization; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0007275 multicellular organism development; GO:0034613 cellular protein localization; GO:0007010 cytoskeleton organization; GO:0045887 positive regulation of synaptic growth at neuromuscular junction; GO:0051254 positive regulation of RNA metabolic process; GO:0006720 isoprenoid metabolic process; GO:0006023 aminoglycan biosynthetic process; GO:0043547 positive regulation of GTPase activity; GO:0048731 system development; GO:0051960 regulation of nervous system development; GO:1901136 carbohydrate derivative catabolic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0050808 synapse organization; GO:1901576 organic substance biosynthetic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0007186 G-protein coupled receptor signaling pathway; GO:0030182 neuron differentiation; GO:0051491 positive regulation of filopodium assembly; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0031325 positive regulation of cellular metabolic process; GO:0095500 acetylcholine receptor signaling pathway; GO:0051179 localization; GO:0031328 positive regulation of cellular biosynthetic process; GO:0050793 regulation of developmental process; GO:1901564 organonitrogen compound metabolic process; GO:0006024 glycosaminoglycan biosynthetic process; GO:0048666 neuron development; GO:0006026 aminoglycan catabolic process; GO:0048869 cellular developmental process; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0051668 localization within membrane; GO:0051130 positive regulation of cellular component organization; GO:0007213 G-protein coupled acetylcholine receptor signaling pathway; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0048469 cell maturation; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0030198 extracellular matrix organization; GO:0033036 macromolecule localization; GO:0070887 cellular response to chemical stimulus; GO:0006629 lipid metabolic process; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0048639 positive regulation of developmental growth; GO:0031326 regulation of cellular biosynthetic process; GO:0051963 regulation of synapse assembly; GO:0051962 positive regulation of nervous system development; GO:0048522 positive regulation of cellular process; GO:1905145 cellular response to acetylcholine; GO:0023052 signaling; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:1901699 cellular response to nitrogen compound; GO:0043087 regulation of GTPase activity; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:1903831 signal transduction involved in cellular response to ammonium ion; GO:0042551 neuron maturation; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0016043 cellular component organization; GO:0040008 regulation of growth; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031344 regulation of cell projection organization; GO:0044087 regulation of cellular component biogenesis; GO:0050896 response to stimulus; GO:1901566 organonitrogen compound biosynthetic process; GO:0048638 regulation of developmental growth; GO:0048468 cell development; GO:0051489 regulation of filopodium assembly; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0001523 retinoid metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006022 aminoglycan metabolic process; GO:0050803 regulation of synapse structure or activity; GO:0006355 regulation of transcription, DNA-templated; GO:1904396 regulation of neuromuscular junction development; GO:0044802 single-organism membrane organization; GO:0006807 nitrogen compound metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0043085 positive regulation of catalytic activity; GO:0070727 cellular macromolecule localization; GO:1901565 organonitrogen compound catabolic process; GO:1901701 cellular response to oxygen-containing compound; GO:0045162 clustering of voltage-gated sodium channels; GO:0044767 single-organism developmental process; GO:0009057 macromolecule catabolic process; GO:0006721 terpenoid metabolic process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0051128 regulation of cellular component organization; GO:0009056 catabolic process; GO:0044089 positive regulation of cellular component biogenesis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044420 extracellular matrix component; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0005604 basement membrane; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0005605 basal lamina; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0005796 Golgi lumen; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0043202 lysosomal lumen; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0045202 synapse; GO:0005886 plasma membrane; GO:0031012 extracellular matrix; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005578 proteinaceous extracellular matrix; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0033691 sialic acid binding; GO:0035374 chondroitin sulfate binding; GO:0002162 dystroglycan binding; GO:0043394 proteoglycan binding; GO:0043167 ion binding; GO:0043395 heparan sulfate proteoglycan binding; GO:0043177 organic acid binding; GO:0005515 protein binding; GO:1901681 sulfur compound binding; GO:0050840 extracellular matrix binding; GO:0097367 carbohydrate derivative binding; GO:0031406 carboxylic acid binding; GO:0043236 laminin binding; GO:0005200 structural constituent of cytoskeleton; GO:0005488 binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0043168 anion binding; GO:0005509 calcium ion binding; GO:0005539 glycosaminoglycan binding; GO:0001948 glycoprotein binding; GO:0005198 structural molecule activity; GO:0036094 small molecule binding; ","K06254","AGRN; agrin","hsa04512 ECM-receptor interaction - Homo sapiens (human); ","IPR008993; IPR002350; IPR001881; IPR000082; IPR000742; IPR001791; IPR013320; IPR003884; IPR002049; IPR004850; IPR003645; ","\"Tissue inhibitor of metalloproteinases-like, OB-fold; Kazal domain; EGF-like calcium-binding domain; SEA domain; EGF-like domain; Laminin G domain; Concanavalin A-like lectin/glucanase domain; Factor I / membrane attack complex; Laminin EGF domain; NtA (N-terminal agrin) domain; Follistatin-like, N-terminal; \"\r"]
["O00471","Exocyst complex component 5 OS=Homo sapiens OX=9606 GN=EXOC5","EXOC5",81.852,18.193,11.4,9,10,8,1.031,0.945,0.971,0.972,0.993,1.017,1.012,0.692,"cytoplasm\r","GO:0098876 vesicle-mediated transport to the plasma membrane; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0048193 Golgi vesicle transport; GO:0071702 organic substance transport; GO:0048278 vesicle docking; GO:0022406 membrane docking; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006810 transport; GO:0045184 establishment of protein localization; GO:1902578 single-organism localization; GO:0032940 secretion by cell; GO:0006893 Golgi to plasma membrane transport; GO:0008104 protein localization; GO:0006892 post-Golgi vesicle-mediated transport; GO:0051179 localization; GO:0033036 macromolecule localization; GO:0009987 cellular process; GO:0006887 exocytosis; GO:0044765 single-organism transport; GO:0046903 secretion; ","GO:0005938 cell cortex; GO:0071944 cell periphery; GO:0099568 cytoplasmic region; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0000145 exocyst; GO:0005829 cytosol; GO:0005623 cell; GO:0005622 intracellular; GO:0044464 cell part; GO:0044448 cell cortex part; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0099023 tethering complex; ","GO:0031267 small GTPase binding; GO:0047485 protein N-terminus binding; GO:0017016 Ras GTPase binding; GO:0005488 binding; GO:0005515 protein binding; GO:0051020 GTPase binding; GO:0017160 Ral GTPase binding; GO:0019899 enzyme binding; ","K19984"]
["O00483","Cytochrome c oxidase subunit NDUFA4 OS=Homo sapiens OX=9606 GN=NDUFA4","NDUFA4",9.3697,19.218,55.6,5,10,5,0.925,0.898,1.07,1.019,1.029,1.046,1.069,0.329,"mitochondria\r","GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0006123 mitochondrial electron transport, cytochrome c to oxygen; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0006753 nucleoside phosphate metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0044765 single-organism transport; GO:0098655 cation transmembrane transport; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006119 oxidative phosphorylation; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0006120 mitochondrial electron transport, NADH to ubiquinone; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0006810 transport; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0022900 electron transport chain; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0098662 inorganic cation transmembrane transport; GO:0016310 phosphorylation; GO:0034220 ion transmembrane transport; GO:0006725 cellular aromatic compound metabolic process; GO:0042773 ATP synthesis coupled electron transport; GO:0009259 ribonucleotide metabolic process; GO:0022904 respiratory electron transport chain; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:1902578 single-organism localization; GO:0006812 cation transport; GO:0006139 nucleobase-containing compound metabolic process; GO:1902600 hydrogen ion transmembrane transport; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009119 ribonucleoside metabolic process; GO:0009987 cellular process; GO:0046034 ATP metabolic process; GO:0098660 inorganic ion transmembrane transport; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0045333 cellular respiration; GO:0006163 purine nucleotide metabolic process; GO:0006818 hydrogen transport; GO:0015992 proton transport; GO:0046128 purine ribonucleoside metabolic process; GO:0055085 transmembrane transport; GO:0006793 phosphorus metabolic process; GO:0006811 ion transport; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0051179 localization; GO:0015672 monovalent inorganic cation transport; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0045271 respiratory chain complex I; GO:0044424 intracellular part; GO:0098798 mitochondrial protein complex; GO:0005747 mitochondrial respiratory chain complex I; GO:0005623 cell; GO:0044455 mitochondrial membrane part; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0005740 mitochondrial envelope; GO:1902494 catalytic complex; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0098803 respiratory chain complex; GO:0005751 mitochondrial respiratory chain complex IV; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0070069 cytochrome complex; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005746 mitochondrial respiratory chain; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0045277 respiratory chain complex IV; GO:0030964 NADH dehydrogenase complex; GO:1990204 oxidoreductase complex; GO:0031975 envelope; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0031966 mitochondrial membrane; GO:0070469 respiratory chain; GO:0044444 cytoplasmic part; ","GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:0003954 NADH dehydrogenase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0050136 NADH dehydrogenase (quinone) activity; GO:0005515 protein binding; GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; GO:0008137 NADH dehydrogenase (ubiquinone) activity; GO:0032403 protein complex binding; GO:0016491 oxidoreductase activity; ","K03948","NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4","hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); "]
["O00487","26S proteasome non-ATPase regulatory subunit 14 OS=Homo sapiens OX=9606 GN=PSMD14","PSMD14",34.577,39.413,18.4,6,10,6,0.923,0.882,0.979,1.072,1.064,1.015,1.132,0.0231,"cytoplasm\r","GO:0044700 single organism signaling; GO:0010608 posttranscriptional regulation of gene expression; GO:0051443 positive regulation of ubiquitin-protein transferase activity; GO:0031347 regulation of defense response; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0070536 protein K63-linked deubiquitination; GO:1903364 positive regulation of cellular protein catabolic process; GO:0008152 metabolic process; GO:0044093 positive regulation of molecular function; GO:0090263 positive regulation of canonical Wnt signaling pathway; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0016055 Wnt signaling pathway; GO:0052548 regulation of endopeptidase activity; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0010950 positive regulation of endopeptidase activity; GO:0006521 regulation of cellular amino acid metabolic process; GO:0080090 regulation of primary metabolic process; GO:0010972 negative regulation of G2/M transition of mitotic cell cycle; GO:0044763 single-organism cellular process; GO:0060828 regulation of canonical Wnt signaling pathway; GO:0043086 negative regulation of catalytic activity; GO:0033209 tumor necrosis factor-mediated signaling pathway; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0000165 MAPK cascade; GO:1901575 organic substance catabolic process; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0007267 cell-cell signaling; GO:0002223 stimulatory C-type lectin receptor signaling pathway; GO:0030163 protein catabolic process; GO:0061136 regulation of proteasomal protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0060071 Wnt signaling pathway, planar cell polarity pathway; GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0016310 phosphorylation; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0006259 DNA metabolic process; GO:1901700 response to oxygen-containing compound; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0043487 regulation of RNA stability; GO:0000209 protein polyubiquitination; GO:0023057 negative regulation of signaling; GO:0046483 heterocycle metabolic process; GO:0010648 negative regulation of cell communication; GO:0051345 positive regulation of hydrolase activity; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0009896 positive regulation of catabolic process; GO:0043620 regulation of DNA-templated transcription in response to stress; GO:0070482 response to oxygen levels; GO:0044248 cellular catabolic process; GO:0042176 regulation of protein catabolic process; GO:0038093 Fc receptor signaling pathway; GO:0050778 positive regulation of immune response; GO:0023014 signal transduction by protein phosphorylation; GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; GO:0016567 protein ubiquitination; GO:0006950 response to stress; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0002263 cell activation involved in immune response; GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress; GO:0006974 cellular response to DNA damage stimulus; GO:1903321 negative regulation of protein modification by small protein conjugation or removal; GO:0045055 regulated exocytosis; GO:0000725 recombinational repair; GO:0031398 positive regulation of protein ubiquitination; GO:0032446 protein modification by small protein conjugation; GO:0031325 positive regulation of cellular metabolic process; GO:0030177 positive regulation of Wnt signaling pathway; GO:1904668 positive regulation of ubiquitin protein ligase activity; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0006955 immune response; GO:0043412 macromolecule modification; GO:0070646 protein modification by small protein removal; GO:0009968 negative regulation of signal transduction; GO:0031331 positive regulation of cellular catabolic process; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0031400 negative regulation of protein modification process; GO:0006796 phosphate-containing compound metabolic process; GO:0031396 regulation of protein ubiquitination; GO:2001141 regulation of RNA biosynthetic process; GO:0045930 negative regulation of mitotic cell cycle; GO:0007165 signal transduction; GO:0009893 positive regulation of metabolic process; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0034612 response to tumor necrosis factor; GO:0051726 regulation of cell cycle; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0006310 DNA recombination; GO:0034097 response to cytokine; GO:0031326 regulation of cellular biosynthetic process; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0198738 cell-cell signaling by wnt; GO:0010565 regulation of cellular ketone metabolic process; GO:0032940 secretion by cell; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0036211 protein modification process; GO:0090175 regulation of establishment of planar polarity; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0045786 negative regulation of cell cycle; GO:0044257 cellular protein catabolic process; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:1901988 negative regulation of cell cycle phase transition; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0006302 double-strand break repair; GO:0010498 proteasomal protein catabolic process; GO:0071704 organic substance metabolic process; GO:0045862 positive regulation of proteolysis; GO:2000027 regulation of organ morphogenesis; GO:0006468 protein phosphorylation; GO:0023056 positive regulation of signaling; GO:0001666 response to hypoxia; GO:0002757 immune response-activating signal transduction; GO:0034641 cellular nitrogen compound metabolic process; GO:0010647 positive regulation of cell communication; GO:0071453 cellular response to oxygen levels; GO:0019221 cytokine-mediated signaling pathway; GO:0031397 negative regulation of protein ubiquitination; GO:0006355 regulation of transcription, DNA-templated; GO:0035556 intracellular signal transduction; GO:0019941 modification-dependent protein catabolic process; GO:0000726 non-recombinational repair; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia; GO:1902749 regulation of cell cycle G2/M phase transition; GO:0043488 regulation of mRNA stability; GO:0043085 positive regulation of catalytic activity; GO:0002366 leukocyte activation involved in immune response; GO:0019882 antigen processing and presentation; GO:0042119 neutrophil activation; GO:0006281 DNA repair; GO:0050852 T cell receptor signaling pathway; GO:0002684 positive regulation of immune system process; GO:0038095 Fc-epsilon receptor signaling pathway; GO:0051248 negative regulation of protein metabolic process; GO:0022402 cell cycle process; GO:1902750 negative regulation of cell cycle G2/M phase transition; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0045321 leukocyte activation; GO:0002220 innate immune response activating cell surface receptor signaling pathway; GO:0007166 cell surface receptor signaling pathway; GO:0071345 cellular response to cytokine stimulus; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0051347 positive regulation of transferase activity; GO:1903362 regulation of cellular protein catabolic process; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0002443 leukocyte mediated immunity; GO:0002758 innate immune response-activating signal transduction; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0031323 regulation of cellular metabolic process; GO:2000058 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0010948 negative regulation of cell cycle process; GO:0051336 regulation of hydrolase activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0002682 regulation of immune system process; GO:0031145 anaphase-promoting complex-dependent catabolic process; GO:0010952 positive regulation of peptidase activity; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0007346 regulation of mitotic cell cycle; GO:0002283 neutrophil activation involved in immune response; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:0051239 regulation of multicellular organismal process; GO:0031349 positive regulation of defense response; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:1901987 regulation of cell cycle phase transition; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0010389 regulation of G2/M transition of mitotic cell cycle; GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; GO:0009966 regulation of signal transduction; GO:0038061 NIK/NF-kappaB signaling; GO:0071456 cellular response to hypoxia; GO:0002253 activation of immune response; GO:0016192 vesicle-mediated transport; GO:0097305 response to alcohol; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1904666 regulation of ubiquitin protein ligase activity; GO:0055085 transmembrane transport; GO:0051247 positive regulation of protein metabolic process; GO:0051438 regulation of ubiquitin-protein transferase activity; GO:0030111 regulation of Wnt signaling pathway; GO:0006793 phosphorus metabolic process; GO:0001775 cell activation; GO:0036293 response to decreased oxygen levels; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process; GO:0006887 exocytosis; GO:0051444 negative regulation of ubiquitin-protein transferase activity; GO:0090090 negative regulation of canonical Wnt signaling pathway; GO:0051234 establishment of localization; GO:0035567 non-canonical Wnt signaling pathway; GO:1905330 regulation of morphogenesis of an epithelium; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:1901991 negative regulation of mitotic cell cycle phase transition; GO:0045088 regulation of innate immune response; GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I; GO:0070887 cellular response to chemical stimulus; GO:0002274 myeloid leukocyte activation; GO:0050851 antigen receptor-mediated signaling pathway; GO:0010468 regulation of gene expression; GO:0030178 negative regulation of Wnt signaling pathway; GO:0048002 antigen processing and presentation of peptide antigen; GO:0002446 neutrophil mediated immunity; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0051348 negative regulation of transferase activity; GO:0070647 protein modification by small protein conjugation or removal; GO:0032268 regulation of cellular protein metabolic process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0090304 nucleic acid metabolic process; GO:0019222 regulation of metabolic process; GO:0043299 leukocyte degranulation; GO:0052547 regulation of peptidase activity; GO:0006303 double-strand break repair via nonhomologous end joining; GO:2000026 regulation of multicellular organismal development; GO:1904667 negative regulation of ubiquitin protein ligase activity; GO:0002218 activation of innate immune response; GO:0006725 cellular aromatic compound metabolic process; GO:0002252 immune effector process; GO:0071356 cellular response to tumor necrosis factor; GO:0045471 response to ethanol; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0016579 protein deubiquitination; GO:1903322 positive regulation of protein modification by small protein conjugation or removal; GO:0006508 proteolysis; GO:0036230 granulocyte activation; GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:0000724 double-strand break repair via homologous recombination; GO:0009987 cellular process; GO:0033238 regulation of cellular amine metabolic process; GO:0043632 modification-dependent macromolecule catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0045089 positive regulation of innate immune response; GO:0006807 nitrogen compound metabolic process; GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition; GO:0031401 positive regulation of protein modification process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0051246 regulation of protein metabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0009057 macromolecule catabolic process; GO:0009967 positive regulation of signal transduction; GO:0045732 positive regulation of protein catabolic process; GO:0036294 cellular response to decreased oxygen levels; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005838 proteasome regulatory particle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:1905369 endopeptidase complex; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0022624 proteasome accessory complex; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0044445 cytosolic part; GO:0030141 secretory granule; GO:1905368 peptidase complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0008541 proteasome regulatory particle, lid subcomplex; GO:0000502 proteasome complex; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0031597 cytosolic proteasome complex; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0008233 peptidase activity; GO:0043167 ion binding; GO:0061134 peptidase regulator activity; GO:0044877 macromolecular complex binding; GO:0016504 peptidase activator activity; GO:0008237 metallopeptidase activity; GO:0061133 endopeptidase activator activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0070628 proteasome binding; GO:0030234 enzyme regulator activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0061578 Lys63-specific deubiquitinase activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0101005 ubiquitinyl hydrolase activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0061135 endopeptidase regulator activity; GO:0008047 enzyme activator activity; GO:0032403 protein complex binding; ","K03030","PSMD14; 26S proteasome regulatory subunit N11","hsa03050 Proteasome - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); ","IPR000555; IPR024969; ","\"JAB1/MPN/MOV34 metalloenzyme domain; Rpn11/EIF3F, C-terminal; \"\r"]
["O00499","Myc box-dependent-interacting protein 1 OS=Homo sapiens OX=9606 GN=BIN1","BIN1",64.699,30.715,10.3,5,6,5,1.073,1.083,1.156,0.885,0.873,0.936,0.813,0.00286,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0060627 regulation of vesicle-mediated transport; GO:0010941 regulation of cell death; GO:0014013 regulation of gliogenesis; GO:0048869 cellular developmental process; GO:0051647 nucleus localization; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0010564 regulation of cell cycle process; GO:0048710 regulation of astrocyte differentiation; GO:0051234 establishment of localization; GO:0045687 positive regulation of glial cell differentiation; GO:0051240 positive regulation of multicellular organismal process; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0032879 regulation of localization; GO:0071825 protein-lipid complex subunit organization; GO:0010720 positive regulation of cell development; GO:0044419 interspecies interaction between organisms; GO:0051726 regulation of cell cycle; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0048699 generation of neurons; GO:0051962 positive regulation of nervous system development; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0060988 lipid tube assembly; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0010942 positive regulation of cell death; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0045664 regulation of neuron differentiation; GO:0065005 protein-lipid complex assembly; GO:0048711 positive regulation of astrocyte differentiation; GO:0051094 positive regulation of developmental process; GO:0048856 anatomical structure development; GO:0043068 positive regulation of programmed cell death; GO:2000026 regulation of multicellular organismal development; GO:0051640 organelle localization; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0006997 nucleus organization; GO:0044707 single-multicellular organism process; GO:0043067 regulation of programmed cell death; GO:0043065 positive regulation of apoptotic process; GO:0045597 positive regulation of cell differentiation; GO:0051239 regulation of multicellular organismal process; GO:0030154 cell differentiation; GO:0016032 viral process; GO:0061061 muscle structure development; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0034622 cellular macromolecular complex assembly; GO:0071156 regulation of cell cycle arrest; GO:0030100 regulation of endocytosis; GO:0051049 regulation of transport; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0008283 cell proliferation; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0045685 regulation of glial cell differentiation; GO:0051641 cellular localization; GO:0043933 macromolecular complex subunit organization; GO:0014015 positive regulation of gliogenesis; GO:0044767 single-organism developmental process; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0042692 muscle cell differentiation; GO:0050769 positive regulation of neurogenesis; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0042981 regulation of apoptotic process; GO:0050767 regulation of neurogenesis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0071944 cell periphery; GO:0030016 myofibril; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0030018 Z disc; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0031674 I band; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0030315 T-tubule; GO:0032994 protein-lipid complex; GO:0044304 main axon; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0043292 contractile fiber; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0043194 axon initial segment; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005635 nuclear envelope; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0015629 actin cytoskeleton; GO:0033267 axon part; GO:0099081 supramolecular polymer; GO:0005886 plasma membrane; GO:0030424 axon; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0060987 lipid tube; GO:0031975 envelope; GO:0030017 sarcomere; GO:0044449 contractile fiber part; GO:0042383 sarcolemma; GO:0033268 node of Ranvier; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0051015 actin filament binding; GO:0042802 identical protein binding; GO:0008092 cytoskeletal protein binding; GO:0005488 binding; GO:0048156 tau protein binding; GO:0044877 macromolecular complex binding; GO:0003779 actin binding; GO:0005515 protein binding; GO:0070063 RNA polymerase binding; GO:0019899 enzyme binding; GO:0032403 protein complex binding; ","K12562","AMPH; amphiphysin","hsa04666 Fc gamma R-mediated phagocytosis - Homo sapiens (human); hsa04144 Endocytosis - Homo sapiens (human); ","IPR001452; IPR027267; IPR004148; ","SH3 domain; Arfaptin homology (AH) domain/BAR domain; BAR domain; \r"]
["O00505","Importin subunit alpha-4 OS=Homo sapiens OX=9606 GN=KPNA3","KPNA3",57.81,15.656,5.2,3,6,1,0.98,0.902,0.953,1.124,1.06,1.025,1.132,0.0271,"cytoplasm\r","GO:0044409 entry into host; GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0006607 NLS-bearing protein import into nucleus; GO:1902594 multi-organism nuclear import; GO:0072594 establishment of protein localization to organelle; GO:0017038 protein import; GO:0044699 single-organism process; GO:1902581 multi-organism cellular localization; GO:0051169 nuclear transport; GO:0044764 multi-organism cellular process; GO:0035821 modification of morphology or physiology of other organism; GO:0015031 protein transport; GO:0044068 modulation by symbiont of host cellular process; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:1902583 multi-organism intracellular transport; GO:0051649 establishment of localization in cell; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0044003 modification by symbiont of host morphology or physiology; GO:0033365 protein localization to organelle; GO:0044419 interspecies interaction between organisms; GO:0075733 intracellular transport of virus; GO:0006606 protein import into nucleus; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0046718 viral entry into host cell; GO:0044765 single-organism transport; GO:0071822 protein complex subunit organization; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0051704 multi-organism process; GO:1902582 single-organism intracellular transport; GO:0006810 transport; GO:0030260 entry into host cell; GO:0050789 regulation of biological process; GO:0051828 entry into other organism involved in symbiotic interaction; GO:0019054 modulation by virus of host process; GO:0006913 nucleocytoplasmic transport; GO:0070271 protein complex biogenesis; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:1902579 multi-organism localization; GO:0016043 cellular component organization; GO:0051806 entry into cell of other organism involved in symbiotic interaction; GO:1902593 single-organism nuclear import; GO:0019058 viral life cycle; GO:0075732 viral penetration into host nucleus; GO:0051817 modification of morphology or physiology of other organism involved in symbiotic interaction; GO:1902578 single-organism localization; GO:0016032 viral process; GO:0006886 intracellular protein transport; GO:0044744 protein targeting to nucleus; GO:1902580 single-organism cellular localization; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0046794 transport of virus; GO:0071702 organic substance transport; GO:0051701 interaction with host; GO:0043933 macromolecular complex subunit organization; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0044766 multi-organism transport; GO:0070727 cellular macromolecule localization; GO:0051170 nuclear import; GO:0051179 localization; GO:0034504 protein localization to nucleus; GO:0019048 modulation by virus of host morphology or physiology; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0005643 nuclear pore; GO:0005635 nuclear envelope; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0031975 envelope; GO:0043227 membrane-bounded organelle; GO:0043234 protein complex; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005048 signal sequence binding; GO:0008565 protein transporter activity; GO:0042277 peptide binding; GO:0005488 binding; GO:0008139 nuclear localization sequence binding; GO:0022892 substrate-specific transporter activity; GO:0008022 protein C-terminus binding; GO:0005515 protein binding; GO:0033218 amide binding; GO:0005215 transporter activity; ",{"$nulls":3},"IPR002652; IPR011989; IPR016024; ","\"Importin-alpha, importin-beta-binding domain; Armadillo-like helical; Armadillo-type fold; \"\r"]
["O00515","Ladinin-1 OS=Homo sapiens OX=9606 GN=LAD1","LAD1",57.13,68.636,23.4,11,14,11,0.769,0.762,0.814,1.251,1.143,1.226,1.544,2.22E-4,"nucleus\r",null,"GO:0031012 extracellular matrix; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0005578 proteinaceous extracellular matrix; GO:0043227 membrane-bounded organelle; GO:0044420 extracellular matrix component; GO:0005576 extracellular region; GO:0043230 extracellular organelle; GO:0005604 basement membrane; ","GO:0050839 cell adhesion molecule binding; GO:0005515 protein binding; GO:0005198 structural molecule activity; GO:0005488 binding; GO:0045296 cadherin binding; "]
["O00534","von Willebrand factor A domain-containing protein 5A OS=Homo sapiens OX=9606 GN=VWA5A","VWA5A",86.488,68.2,22.4,14,17,14,1.092,1.029,0.996,0.971,0.97,0.986,0.939,0.0862,"nucleus\r",{"$nulls":6},"IPR013694; IPR002035; ","\"VIT domain; von Willebrand factor, type A; \"\r"]
["O00560","Syntenin-1 OS=Homo sapiens OX=9606 GN=SDCBP","SDCBP",32.444,2.4804,3.4,1,1,1,1.029,1.062,0.907,1.027,1.003,0.985,1.006,0.883,"cytoskeleton\r","GO:0060627 regulation of vesicle-mediated transport; GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0030335 positive regulation of cell migration; GO:0032872 regulation of stress-activated MAPK cascade; GO:0010717 regulation of epithelial to mesenchymal transition; GO:0045321 leukocyte activation; GO:0032270 positive regulation of cellular protein metabolic process; GO:0007166 cell surface receptor signaling pathway; GO:0015031 protein transport; GO:0045927 positive regulation of growth; GO:0001558 regulation of cell growth; GO:0090100 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0030036 actin cytoskeleton organization; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0010562 positive regulation of phosphorus metabolic process; GO:0042327 positive regulation of phosphorylation; GO:0008104 protein localization; GO:1903362 regulation of cellular protein catabolic process; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0006930 substrate-dependent cell migration, cell extension; GO:0051051 negative regulation of transport; GO:1903543 positive regulation of exosomal secretion; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0002443 leukocyte mediated immunity; GO:0051174 regulation of phosphorus metabolic process; GO:0048259 regulation of receptor-mediated endocytosis; GO:0072657 protein localization to membrane; GO:0030307 positive regulation of cell growth; GO:0045921 positive regulation of exocytosis; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0090287 regulation of cellular response to growth factor stimulus; GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation; GO:0048870 cell motility; GO:0051272 positive regulation of cellular component movement; GO:0031323 regulation of cellular metabolic process; GO:0006810 transport; GO:0048261 negative regulation of receptor-mediated endocytosis; GO:0007267 cell-cell signaling; GO:0080135 regulation of cellular response to stress; GO:0032874 positive regulation of stress-activated MAPK cascade; GO:0032269 negative regulation of cellular protein metabolic process; GO:0061136 regulation of proteasomal protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051094 positive regulation of developmental process; GO:0002091 negative regulation of receptor internalization; GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0051047 positive regulation of secretion; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0007346 regulation of mitotic cell cycle; GO:0002283 neutrophil activation involved in immune response; GO:0042127 regulation of cell proliferation; GO:1903051 negative regulation of proteolysis involved in cellular protein catabolic process; GO:0031399 regulation of protein modification process; GO:0017157 regulation of exocytosis; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:2000147 positive regulation of cell motility; GO:1903541 regulation of exosomal secretion; GO:1901799 negative regulation of proteasomal protein catabolic process; GO:0051239 regulation of multicellular organismal process; GO:0045597 positive regulation of cell differentiation; GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0045806 negative regulation of endocytosis; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:2000145 regulation of cell motility; GO:0042176 regulation of protein catabolic process; GO:0007010 cytoskeleton organization; GO:0034613 cellular protein localization; GO:0090150 establishment of protein localization to membrane; GO:0009966 regulation of signal transduction; GO:0045861 negative regulation of proteolysis; GO:0030100 regulation of endocytosis; GO:1902531 regulation of intracellular signal transduction; GO:0051270 regulation of cellular component movement; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0030334 regulation of cell migration; GO:0071702 organic substance transport; GO:0030162 regulation of proteolysis; GO:0009892 negative regulation of metabolic process; GO:0002263 cell activation involved in immune response; GO:0030031 cell projection assembly; GO:0045184 establishment of protein localization; GO:0031330 negative regulation of cellular catabolic process; GO:0045055 regulated exocytosis; GO:0051247 positive regulation of protein metabolic process; GO:0099536 synaptic signaling; GO:0010718 positive regulation of epithelial to mesenchymal transition; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0031325 positive regulation of cellular metabolic process; GO:0001775 cell activation; GO:0006928 movement of cell or subcellular component; GO:0007268 chemical synaptic transmission; GO:0006955 immune response; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:0050793 regulation of developmental process; GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway; GO:0008284 positive regulation of cell proliferation; GO:0006887 exocytosis; GO:0046330 positive regulation of JNK cascade; GO:0051674 localization of cell; GO:0040017 positive regulation of locomotion; GO:0051129 negative regulation of cellular component organization; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0051046 regulation of secretion; GO:1902115 regulation of organelle assembly; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0051130 positive regulation of cellular component organization; GO:0006612 protein targeting to membrane; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0070302 regulation of stress-activated protein kinase signaling cascade; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0022607 cellular component assembly; GO:0070304 positive regulation of stress-activated protein kinase signaling cascade; GO:0098916 anterograde trans-synaptic signaling; GO:0033036 macromolecule localization; GO:0006929 substrate-dependent cell migration; GO:0051726 regulation of cell cycle; GO:0046328 regulation of JNK cascade; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0002274 myeloid leukocyte activation; GO:0045937 positive regulation of phosphate metabolic process; GO:1903846 positive regulation of cellular response to transforming growth factor beta stimulus; GO:0002446 neutrophil mediated immunity; GO:0048522 positive regulation of cellular process; GO:1903363 negative regulation of cellular protein catabolic process; GO:0023052 signaling; GO:1903530 regulation of secretion by cell; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0051050 positive regulation of transport; GO:1902589 single-organism organelle organization; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0010638 positive regulation of organelle organization; GO:0030030 cell projection organization; GO:1903532 positive regulation of secretion by cell; GO:0032940 secretion by cell; GO:1902117 positive regulation of organelle assembly; GO:0019222 regulation of metabolic process; GO:0043299 leukocyte degranulation; GO:0019220 regulation of phosphate metabolic process; GO:0040011 locomotion; GO:2000026 regulation of multicellular organismal development; GO:0016043 cellular component organization; GO:0016477 cell migration; GO:0040008 regulation of growth; GO:0042177 negative regulation of protein catabolic process; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0017015 regulation of transforming growth factor beta receptor signaling pathway; GO:0044087 regulation of cellular component biogenesis; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0048013 ephrin receptor signaling pathway; GO:0060393 regulation of pathway-restricted SMAD protein phosphorylation; GO:0043408 regulation of MAPK cascade; GO:0023056 positive regulation of signaling; GO:0006886 intracellular protein transport; GO:0099537 trans-synaptic signaling; GO:0009895 negative regulation of catabolic process; GO:0036230 granulocyte activation; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:0002090 regulation of receptor internalization; GO:0045595 regulation of cell differentiation; GO:1903553 positive regulation of extracellular exosome assembly; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:1903551 regulation of extracellular exosome assembly; GO:0035556 intracellular signal transduction; GO:0051049 regulation of transport; GO:0001932 regulation of protein phosphorylation; GO:0031401 positive regulation of protein modification process; GO:0033043 regulation of organelle organization; GO:0043312 neutrophil degranulation; GO:0001934 positive regulation of protein phosphorylation; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0002366 leukocyte activation involved in immune response; GO:1903844 regulation of cellular response to transforming growth factor beta stimulus; GO:0042119 neutrophil activation; GO:0070727 cellular macromolecule localization; GO:0051246 regulation of protein metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0009967 positive regulation of signal transduction; GO:0051128 regulation of cellular component organization; GO:0040012 regulation of locomotion; GO:0043410 positive regulation of MAPK cascade; GO:0044089 positive regulation of cellular component biogenesis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0098857 membrane microdomain; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0035578 azurophil granule lumen; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0031965 nuclear membrane; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:0098589 membrane region; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0031226 intrinsic component of plasma membrane; GO:0031967 organelle envelope; GO:0098802 plasma membrane receptor complex; GO:0070161 anchoring junction; GO:0043235 receptor complex; GO:0031981 nuclear lumen; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0042582 azurophil granule; GO:0043231 intracellular membrane-bounded organelle; GO:0005766 primary lysosome; GO:0031975 envelope; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043230 extracellular organelle; GO:0034774 secretory granule lumen; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0005615 extracellular space; GO:0031410 cytoplasmic vesicle; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005895 interleukin-5 receptor complex; GO:0048770 pigment granule; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0045121 membrane raft; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005635 nuclear envelope; GO:0042470 melanosome; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0016021 integral component of membrane; GO:0043226 organelle; GO:0072562 blood microparticle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0060205 cytoplasmic vesicle lumen; GO:0044432 endoplasmic reticulum part; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:1901981 phosphatidylinositol phosphate binding; GO:0005137 interleukin-5 receptor binding; GO:0030674 protein binding, bridging; GO:0047485 protein N-terminus binding; GO:0046982 protein heterodimerization activity; GO:0005102 receptor binding; GO:0043394 proteoglycan binding; GO:0046983 protein dimerization activity; GO:0043167 ion binding; GO:0005109 frizzled binding; GO:0005126 cytokine receptor binding; GO:0070851 growth factor receptor binding; GO:0005515 protein binding; GO:1902936 phosphatidylinositol bisphosphate binding; GO:0050839 cell adhesion molecule binding; GO:0045545 syndecan binding; GO:0097367 carbohydrate derivative binding; GO:0008092 cytoskeletal protein binding; GO:0042802 identical protein binding; GO:0008093 cytoskeletal adaptor activity; GO:0005488 binding; GO:0005546 phosphatidylinositol-4,5-bisphosphate binding; GO:0045296 cadherin binding; GO:0035091 phosphatidylinositol binding; GO:0005543 phospholipid binding; GO:0008289 lipid binding; GO:0060090 binding, bridging; GO:0043168 anion binding; GO:0001664 G-protein coupled receptor binding; GO:0001948 glycoprotein binding; ","K17254",null,null,"IPR001478; ","PDZ domain; \r"]
["O00567","Nucleolar protein 56 OS=Homo sapiens OX=9606 GN=NOP56","NOP56",66.049,61.755,17,8,10,8,0.843,0.927,1.065,1.03,1.07,1.043,1.109,0.193,"nucleus\r","GO:0016072 rRNA metabolic process; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0006725 cellular aromatic compound metabolic process; GO:0000154 rRNA modification; GO:0006807 nitrogen compound metabolic process; GO:0042254 ribosome biogenesis; GO:1901360 organic cyclic compound metabolic process; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0009451 RNA modification; GO:0071704 organic substance metabolic process; GO:0016070 RNA metabolic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0090304 nucleic acid metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0006364 rRNA processing; GO:0044260 cellular macromolecule metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0010467 gene expression; GO:0043170 macromolecule metabolic process; GO:0043412 macromolecule modification; GO:0009987 cellular process; GO:0034660 ncRNA metabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0030684 preribosome; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0032040 small-subunit processome; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044452 nucleolar part; GO:0005730 nucleolus; GO:0001650 fibrillar center; GO:0070761 pre-snoRNP complex; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0005732 small nucleolar ribonucleoprotein complex; GO:0031428 box C/D snoRNP complex; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0044428 nuclear part; ","GO:0030515 snoRNA binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0050839 cell adhesion molecule binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0003676 nucleic acid binding; GO:1990226 histone methyltransferase binding; GO:0005515 protein binding; GO:0019899 enzyme binding; ","K14564","NOP56; nucleolar protein 56","hsa03008 Ribosome biogenesis in eukaryotes - Homo sapiens (human); ","IPR002687; IPR012974; IPR012976; ","\"Nop domain; NOP5, N-terminal; NOSIC; \"\r"]
["O00571","ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X","DDX3X",73.243,82.994,32.9,19,29,18,0.893,0.876,0.861,1.073,1.124,1.058,1.238,0.000541,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0010608 posttranscriptional regulation of gene expression; GO:0009891 positive regulation of biosynthetic process; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0009607 response to biotic stimulus; GO:0045927 positive regulation of growth; GO:0001558 regulation of cell growth; GO:0010466 negative regulation of peptidase activity; GO:0008152 metabolic process; GO:0065003 macromolecular complex assembly; GO:0044093 positive regulation of molecular function; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0090068 positive regulation of cell cycle process; GO:0016055 Wnt signaling pathway; GO:0031333 negative regulation of protein complex assembly; GO:0052548 regulation of endopeptidase activity; GO:0051716 cellular response to stimulus; GO:0007059 chromosome segregation; GO:0071214 cellular response to abiotic stimulus; GO:0010950 positive regulation of endopeptidase activity; GO:0030307 positive regulation of cell growth; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0034249 negative regulation of cellular amide metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0043086 negative regulation of catalytic activity; GO:0042256 mature ribosome assembly; GO:0051704 multi-organism process; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0006810 transport; GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0045931 positive regulation of mitotic cell cycle; GO:0007267 cell-cell signaling; GO:1902532 negative regulation of intracellular signal transduction; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0060548 negative regulation of cell death; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0097190 apoptotic signaling pathway; GO:2001056 positive regulation of cysteine-type endopeptidase activity; GO:0001819 positive regulation of cytokine production; GO:0048519 negative regulation of biological process; GO:1901989 positive regulation of cell cycle phase transition; GO:0023057 negative regulation of signaling; GO:0046483 heterocycle metabolic process; GO:0010648 negative regulation of cell communication; GO:0006139 nucleobase-containing compound metabolic process; GO:0051345 positive regulation of hydrolase activity; GO:0009889 regulation of biosynthetic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0034613 cellular protein localization; GO:0010501 RNA secondary structure unwinding; GO:0045861 negative regulation of proteolysis; GO:0071243 cellular response to arsenic-containing substance; GO:0006950 response to stress; GO:0032648 regulation of interferon-beta production; GO:0002376 immune system process; GO:0002263 cell activation involved in immune response; GO:1901576 organic substance biosynthetic process; GO:0034248 regulation of cellular amide metabolic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0045055 regulated exocytosis; GO:0009890 negative regulation of biosynthetic process; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0006955 immune response; GO:2000045 regulation of G1/S transition of mitotic cell cycle; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0032392 DNA geometric change; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0009893 positive regulation of metabolic process; GO:0032642 regulation of chemokine production; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:1902806 regulation of cell cycle G1/S phase transition; GO:0006915 apoptotic process; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0033036 macromolecule localization; GO:0051726 regulation of cell cycle; GO:1903902 positive regulation of viral life cycle; GO:0045926 negative regulation of growth; GO:0043902 positive regulation of multi-organism process; GO:0006970 response to osmotic stress; GO:0031326 regulation of cellular biosynthetic process; GO:2000116 regulation of cysteine-type endopeptidase activity; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0010942 positive regulation of cell death; GO:0198738 cell-cell signaling by wnt; GO:0006351 transcription, DNA-templated; GO:0032940 secretion by cell; GO:0071649 regulation of chemokine (C-C motif) ligand 5 production; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0006952 defense response; GO:0032722 positive regulation of chemokine production; GO:0009615 response to virus; GO:0016043 cellular component organization; GO:0032479 regulation of type I interferon production; GO:0043069 negative regulation of programmed cell death; GO:0040008 regulation of growth; GO:0060255 regulation of macromolecule metabolic process; GO:0043065 positive regulation of apoptotic process; GO:0097193 intrinsic apoptotic signaling pathway; GO:0051707 response to other organism; GO:0045087 innate immune response; GO:0051346 negative regulation of hydrolase activity; GO:0071704 organic substance metabolic process; GO:0045862 positive regulation of proteolysis; GO:0043066 negative regulation of apoptotic process; GO:0070925 organelle assembly; GO:0016032 viral process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0045070 positive regulation of viral genome replication; GO:0034622 cellular macromolecular complex assembly; GO:0006355 regulation of transcription, DNA-templated; GO:0035556 intracellular signal transduction; GO:0010629 negative regulation of gene expression; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0043085 positive regulation of catalytic activity; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0048524 positive regulation of viral process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0008219 cell death; GO:0001817 regulation of cytokine production; GO:0051248 negative regulation of protein metabolic process; GO:0010467 gene expression; GO:0031327 negative regulation of cellular biosynthetic process; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0032481 positive regulation of type I interferon production; GO:0022613 ribonucleoprotein complex biogenesis; GO:1903608 protein localization to cytoplasmic stress granule; GO:0032270 positive regulation of cellular protein metabolic process; GO:0045321 leukocyte activation; GO:0022618 ribonucleoprotein complex assembly; GO:0007166 cell surface receptor signaling pathway; GO:0097659 nucleic acid-templated transcription; GO:0046685 response to arsenic-containing substance; GO:0009605 response to external stimulus; GO:0051240 positive regulation of multicellular organismal process; GO:0033365 protein localization to organelle; GO:0043170 macromolecule metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0008104 protein localization; GO:0044419 interspecies interaction between organisms; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0018130 heterocycle biosynthetic process; GO:0002443 leukocyte mediated immunity; GO:0045893 positive regulation of transcription, DNA-templated; GO:0042254 ribosome biogenesis; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0071470 cellular response to osmotic stress; GO:0043068 positive regulation of programmed cell death; GO:0010952 positive regulation of peptidase activity; GO:1901362 organic cyclic compound biosynthetic process; GO:0050794 regulation of cellular process; GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0033554 cellular response to stress; GO:0007346 regulation of mitotic cell cycle; GO:0010951 negative regulation of endopeptidase activity; GO:0097191 extrinsic apoptotic signaling pathway; GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors; GO:0002283 neutrophil activation involved in immune response; GO:0009628 response to abiotic stimulus; GO:0043067 regulation of programmed cell death; GO:0017148 negative regulation of translation; GO:0048523 negative regulation of cellular process; GO:0051239 regulation of multicellular organismal process; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0019438 aromatic compound biosynthetic process; GO:1901987 regulation of cell cycle phase transition; GO:0010628 positive regulation of gene expression; GO:0051171 regulation of nitrogen compound metabolic process; GO:0009966 regulation of signal transduction; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0045787 positive regulation of cell cycle; GO:0051254 positive regulation of RNA metabolic process; GO:1902531 regulation of intracellular signal transduction; GO:0043900 regulation of multi-organism process; GO:0016192 vesicle-mediated transport; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0042255 ribosome assembly; GO:1900087 positive regulation of G1/S transition of mitotic cell cycle; GO:0034063 stress granule assembly; GO:0051247 positive regulation of protein metabolic process; GO:0051276 chromosome organization; GO:0001775 cell activation; GO:0012501 programmed cell death; GO:0051179 localization; GO:0031328 positive regulation of cellular biosynthetic process; GO:0006887 exocytosis; GO:0051129 negative regulation of cellular component organization; GO:0044764 multi-organism cellular process; GO:0051234 establishment of localization; GO:2001233 regulation of apoptotic signaling pathway; GO:0010646 regulation of cell communication; GO:0071826 ribonucleoprotein complex subunit organization; GO:0007154 cell communication; GO:2001243 negative regulation of intrinsic apoptotic signaling pathway; GO:0022607 cellular component assembly; GO:0070887 cellular response to chemical stimulus; GO:0071103 DNA conformation change; GO:0002274 myeloid leukocyte activation; GO:0010468 regulation of gene expression; GO:0045727 positive regulation of translation; GO:0002446 neutrophil mediated immunity; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0045069 regulation of viral genome replication; GO:0030308 negative regulation of cell growth; GO:0016070 RNA metabolic process; GO:0032268 regulation of cellular protein metabolic process; GO:0043254 regulation of protein complex assembly; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0090304 nucleic acid metabolic process; GO:0019222 regulation of metabolic process; GO:0043299 leukocyte degranulation; GO:1902808 positive regulation of cell cycle G1/S phase transition; GO:0052547 regulation of peptidase activity; GO:0006725 cellular aromatic compound metabolic process; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0002252 immune effector process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044087 regulation of cellular component biogenesis; GO:0043207 response to external biotic stimulus; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production; GO:2000117 negative regulation of cysteine-type endopeptidase activity; GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0032508 DNA duplex unwinding; GO:0045948 positive regulation of translational initiation; GO:0050792 regulation of viral process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0043312 neutrophil degranulation; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0032728 positive regulation of interferon-beta production; GO:0070727 cellular macromolecule localization; GO:0006417 regulation of translation; GO:0051246 regulation of protein metabolic process; GO:2001242 regulation of intrinsic apoptotic signaling pathway; GO:0034250 positive regulation of cellular amide metabolic process; GO:0006446 regulation of translational initiation; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0051128 regulation of cellular component organization; GO:1903900 regulation of viral life cycle; GO:1901992 positive regulation of mitotic cell cycle phase transition; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0016020 membrane; GO:0019867 outer membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005740 mitochondrial envelope; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0101002 ficolin-1-rich granule; GO:0031983 vesicle lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0031968 organelle outer membrane; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0010494 cytoplasmic stress granule; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005741 mitochondrial outer membrane; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0031975 envelope; GO:0035770 ribonucleoprotein granule; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0031966 mitochondrial membrane; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0048027 mRNA 5'-UTR binding; GO:1901265 nucleoside phosphate binding; GO:0008026 ATP-dependent helicase activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0043273 CTPase activity; GO:0016887 ATPase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0003729 mRNA binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0043024 ribosomal small subunit binding; GO:0031369 translation initiation factor binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0032550 purine ribonucleoside binding; GO:0004003 ATP-dependent DNA helicase activity; GO:0003924 GTPase activity; GO:0008190 eukaryotic initiation factor 4E binding; GO:0004004 ATP-dependent RNA helicase activity; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0008094 DNA-dependent ATPase activity; GO:0003678 DNA helicase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0008143 poly(A) binding; GO:0003723 RNA binding; GO:0003677 DNA binding; GO:0035613 RNA stem-loop binding; GO:0070035 purine NTP-dependent helicase activity; GO:0005524 ATP binding; GO:0004386 helicase activity; GO:0008186 RNA-dependent ATPase activity; GO:0001882 nucleoside binding; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0070717 poly-purine tract binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0003727 single-stranded RNA binding; GO:0050839 cell adhesion molecule binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003724 RNA helicase activity; GO:0003676 nucleic acid binding; GO:0042623 ATPase activity, coupled; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0008134 transcription factor binding; GO:0043021 ribonucleoprotein complex binding; GO:0036094 small molecule binding; ","K11594","DDX3X; ATP-dependent RNA helicase DDX3X [EC:3.6.4.13]","hsa04622 RIG-I-like receptor signaling pathway - Homo sapiens (human); hsa05161 Hepatitis B - Homo sapiens (human); hsa05203 Viral carcinogenesis - Homo sapiens (human); ","IPR014014; IPR011545; IPR014001; IPR027417; IPR001650; ","\"RNA helicase, DEAD-box type, Q motif; DEAD/DEAH box helicase domain; Helicase superfamily 1/2, ATP-binding domain; P-loop containing nucleoside triphosphate hydrolase; Helicase, C-terminal; \"\r"]
["O00584","Ribonuclease T2 OS=Homo sapiens OX=9606 GN=RNASET2","RNASET2",29.48,8.492,9,2,3,2,1.102,1.035,1.043,0.994,0.953,0.893,0.893,0.0369,"extracellular\r","GO:0045321 leukocyte activation; GO:0002283 neutrophil activation involved in immune response; GO:0006725 cellular aromatic compound metabolic process; GO:0002252 immune effector process; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0051234 establishment of localization; GO:0044270 cellular nitrogen compound catabolic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0006139 nucleobase-containing compound metabolic process; GO:0044248 cellular catabolic process; GO:1901361 organic cyclic compound catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0002274 myeloid leukocyte activation; GO:0044265 cellular macromolecule catabolic process; GO:0002443 leukocyte mediated immunity; GO:0016192 vesicle-mediated transport; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:0043312 neutrophil degranulation; GO:0002263 cell activation involved in immune response; GO:0002444 myeloid leukocyte mediated immunity; GO:0016070 RNA metabolic process; GO:0006401 RNA catabolic process; GO:0002366 leukocyte activation involved in immune response; GO:0006810 transport; GO:0019439 aromatic compound catabolic process; GO:1901575 organic substance catabolic process; GO:0090501 RNA phosphodiester bond hydrolysis; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0090304 nucleic acid metabolic process; GO:0032940 secretion by cell; GO:0009057 macromolecule catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0001775 cell activation; GO:0043299 leukocyte degranulation; GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic; GO:0090305 nucleic acid phosphodiester bond hydrolysis; GO:0006955 immune response; GO:0051179 localization; GO:0009056 catabolic process; GO:0046700 heterocycle catabolic process; GO:0006887 exocytosis; ","GO:0034774 secretory granule lumen; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0005788 endoplasmic reticulum lumen; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0043202 lysosomal lumen; GO:0005576 extracellular region; GO:0042582 azurophil granule; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0044432 endoplasmic reticulum part; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0003723 RNA binding; GO:0004521 endoribonuclease activity; GO:0016787 hydrolase activity; GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0003824 catalytic activity; GO:0033897 ribonuclease T2 activity; GO:0005488 binding; GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters; GO:0003676 nucleic acid binding; GO:0004518 nuclease activity; GO:0016788 hydrolase activity, acting on ester bonds; GO:0004540 ribonuclease activity; GO:0004519 endonuclease activity; ","K01166"]
["O00585","C-C motif chemokine 21 OS=Homo sapiens OX=9606 GN=CCL21","CCL21",14.646,5.1891,9.7,1,1,1,0.867,0.73,0.816,1.209,1.156,1.205,1.479,0.00168,"extracellular\r",{"$cut":{"chars":16924,"head":"GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0002694 regulation of leukocyte activation; GO:0010941 regulation of cell death; GO:0021700 developmental maturation; GO:0032872 regulation of stress-activated MAPK cascade; GO:0097026 dendritic cell dendrite assembly; GO:0009891 positive regulation of biosynthetic process; GO:0070555 response to interleukin-1; GO:0035759 mesangial cell-matrix adhesion; GO:0042110 T cell activation; GO:0048247 lymphocyte chemotaxis; GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling; GO:0032535 regulation of cellular component size; GO:0044093 positive regulation of molecular function; GO:0055065 metal ion homeostasis; GO:0007160 cell-matrix adhesion; GO:0051493 regulation of cytoskeleton organization; GO:0090022 regulation of neutrophil chemotaxis; GO:0001954 positive regulation of cell-matrix adhesion; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0048259 regulation of receptor-mediated endocytosis; GO:0080090 regulation of primary metabolic process; GO:1903038 negative regulation of leukocyte cell-cell adhesion; GO:0044763 single-organism cellular process; GO:0048870 cell motility; GO:0006935 chemotaxis; GO:0010811 positive regulation of cell-substrate adhesion; GO:0006874 cellular calcium ion homeostasis; GO:0006810 transport; GO:0007267 cell-cell signaling; GO:0080135 regulation of cellular response to stress; GO:0031274 positive regulation of pseudopodium assembly; GO:0032874 positive regulation of stress-activated MAPK cascade; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:1902905 positive regulation of supramolecular fiber organization; GO:0060548 negative regulation of cell death; GO:0098662 inorganic cation transmembrane transport; GO:0002687 positive regulation of leukocyte migration; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0034220 ion transmembrane transport; GO:0030001 metal ion transport; GO:1901700 response to oxygen-containing compound; GO:0009988 cell-cell recognition; GO:0022408 negative regulation of cell-cell adhesion; GO:0048519 negative regulation of biological process; GO:0002579 positive regulation of antigen processing and presentation; GO:0050867 positive regulation of cell activation; GO:0051345 positive regulation of hydrolase activity; GO:0009889 regulation of biosynthetic process; GO:2000145 regulation of cell motility; GO:0031345 negative regulation of cell projection organization; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:2000403 positive regulation of lymphocyte migration; GO:0002604 regulation of dendritic cell antigen processing and presentation; GO:0048878 chemical homeostasis; GO:0070588 calcium ion transmembrane transport; GO:0036336 dendritic cell migration; GO:0030100 regulation of endocytosis; GO:0051282 regulation of sequestering of calcium ion; GO:0045785 positive regulation of cell adhesion; GO:0006950 response to stress; GO:0051270 regulation of cellular component movement; GO:0034694 response to prostaglandin; GO:1903018 regulation of glycoprotein metabolic process; GO:0032970 regulation of actin filament-based process; GO:1902656 calcium ion import into cytosol; GO:0032101 regulation of response to external stimulus; GO:0002376 immune system process; GO:2000529 positive regulation of myeloid dendritic cell chemotaxis; GO:0010033 response to organic substance; GO:0002548 monocyte chemotaxis; GO:1903039 positive regulation of leukocyte cell-cell adhesion; GO:0007186 G-protein coupled receptor signaling pathway; GO:0071674 mononuclear cell migration; GO:0002696 positive regulation of leukocyte activation; GO:0051491 positive regulation of filopodium assembly; GO:0030336 negative regulation of cell migration; GO:0001767 establishment of lymphocyte polarity; GO:0031325 positive regulation of cellular metabolic process; GO:1903727 positive regulation of phospholipid metabolic process; GO:0006955 immune response; GO:2000107 negative regulation of"}},"GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005623 cell; GO:0005576 extracellular region; ","GO:0031732 CCR7 chemokine receptor binding; GO:0005125 cytokine activity; GO:0048020 CCR chemokine receptor binding; GO:0005102 receptor binding; GO:0005488 binding; GO:0042379 chemokine receptor binding; GO:0005126 cytokine receptor binding; GO:0001664 G-protein coupled receptor binding; GO:0005515 protein binding; GO:0008009 chemokine activity; ","K16062","CCL21; C-C motif chemokine 21","hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human); hsa04064 NF-kappa B signaling pathway - Homo sapiens (human); hsa04062 Chemokine signaling pathway - Homo sapiens (human); ","IPR034133; IPR001811; ","\"Chemokine CC, DCCL motif-cointaining domain; Chemokine interleukin-8-like domain; \"\r"]
["O00629","Importin subunit alpha-3 OS=Homo sapiens OX=9606 GN=KPNA4","KPNA4",57.886,45.622,12.5,5,6,3,0.844,0.934,1.092,0.973,1.021,1.13,1.089,0.366,"cytoplasm\r","GO:0065008 regulation of biological quality; GO:0006607 NLS-bearing protein import into nucleus; GO:0072594 establishment of protein localization to organelle; GO:0017038 protein import; GO:0044699 single-organism process; GO:1902581 multi-organism cellular localization; GO:0051169 nuclear transport; GO:0044764 multi-organism cellular process; GO:0035821 modification of morphology or physiology of other organism; GO:0015031 protein transport; GO:0044068 modulation by symbiont of host cellular process; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:1902583 multi-organism intracellular transport; GO:0051649 establishment of localization in cell; GO:0044003 modification by symbiont of host morphology or physiology; GO:0006979 response to oxidative stress; GO:0010035 response to inorganic substance; GO:0033365 protein localization to organelle; GO:0075733 intracellular transport of virus; GO:0044419 interspecies interaction between organisms; GO:0006606 protein import into nucleus; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0044765 single-organism transport; GO:0000302 response to reactive oxygen species; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0051704 multi-organism process; GO:1902582 single-organism intracellular transport; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0019054 modulation by virus of host process; GO:0006913 nucleocytoplasmic transport; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:1902579 multi-organism localization; GO:1902593 single-organism nuclear import; GO:0019058 viral life cycle; GO:1901700 response to oxygen-containing compound; GO:0050896 response to stimulus; GO:0051817 modification of morphology or physiology of other organism involved in symbiotic interaction; GO:1902578 single-organism localization; GO:0016032 viral process; GO:0006886 intracellular protein transport; GO:0044744 protein targeting to nucleus; GO:1902580 single-organism cellular localization; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0006950 response to stress; GO:0046794 transport of virus; GO:0071702 organic substance transport; GO:0051701 interaction with host; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0044766 multi-organism transport; GO:0070727 cellular macromolecule localization; GO:0051170 nuclear import; GO:0042542 response to hydrogen peroxide; GO:0051179 localization; GO:0034504 protein localization to nucleus; GO:0019048 modulation by virus of host morphology or physiology; GO:0065007 biological regulation; ","GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005643 nuclear pore; GO:0005635 nuclear envelope; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0031975 envelope; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005048 signal sequence binding; GO:0008565 protein transporter activity; GO:0042277 peptide binding; GO:0005488 binding; GO:0008139 nuclear localization sequence binding; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0033218 amide binding; GO:0005215 transporter activity; ",{"$nulls":3},"IPR002652; IPR011989; IPR016024; ","\"Importin-alpha, importin-beta-binding domain; Armadillo-like helical; Armadillo-type fold; \"\r"]
["O00743","Serine/threonine-protein phosphatase 6 catalytic subunit OS=Homo sapiens OX=9606 GN=PPP6C","PPP6C",35.144,7.0818,9.8,3,4,3,1.011,0.81,1.063,1.167,0.904,1.049,1.082,0.513,"extracellular\r","GO:0044085 cellular component biogenesis; GO:0051640 organelle localization; GO:0016043 cellular component organization; GO:0006901 vesicle coating; GO:0046907 intracellular transport; GO:0048207 vesicle targeting, rough ER to cis-Golgi; GO:0048208 COPII vesicle coating; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0048193 Golgi vesicle transport; GO:0006903 vesicle targeting; GO:0044237 cellular metabolic process; GO:1903047 mitotic cell cycle process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0051648 vesicle localization; GO:0048199 vesicle targeting, to, from or within Golgi; GO:0044770 cell cycle phase transition; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0000082 G1/S transition of mitotic cell cycle; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0044772 mitotic cell cycle phase transition; GO:0000278 mitotic cell cycle; GO:0051650 establishment of vesicle localization; GO:0071822 protein complex subunit organization; GO:0044843 cell cycle G1/S phase transition; GO:0090114 COPII-coated vesicle budding; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0016050 vesicle organization; GO:0006470 protein dephosphorylation; GO:0044238 primary metabolic process; GO:0051656 establishment of organelle localization; GO:0016311 dephosphorylation; GO:0043933 macromolecular complex subunit organization; GO:0051641 cellular localization; GO:0006810 transport; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0006900 membrane budding; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0022402 cell cycle process; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:0051179 localization; GO:0070271 protein complex biogenesis; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0098588 bounding membrane of organelle; GO:0031090 organelle membrane; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005622 intracellular; GO:0044464 cell part; GO:0044431 Golgi apparatus part; GO:0005794 Golgi apparatus; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0003824 catalytic activity; GO:0042578 phosphoric ester hydrolase activity; GO:0005488 binding; GO:0004722 protein serine/threonine phosphatase activity; GO:0016791 phosphatase activity; GO:0043167 ion binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0004721 phosphoprotein phosphatase activity; ","K15498",null,null,"IPR029052; IPR004843; IPR006186; ","\"Metallo-dependent phosphatase-like; Calcineurin-like phosphoesterase domain, ApaH type; Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase; \"\r"]
["O00754","Lysosomal alpha-mannosidase OS=Homo sapiens OX=9606 GN=MAN2B1","MAN2B1",113.74,38.685,9.5,7,10,7,0.97,1.087,0.923,0.994,0.98,1.06,1.018,0.734,"extracellular\r","GO:0045321 leukocyte activation; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0006517 protein deglycosylation; GO:0009313 oligosaccharide catabolic process; GO:0044267 cellular protein metabolic process; GO:0006013 mannose metabolic process; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0005996 monosaccharide metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0036230 granulocyte activation; GO:0009311 oligosaccharide metabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0009987 cellular process; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0002443 leukocyte mediated immunity; GO:0044724 single-organism carbohydrate catabolic process; GO:0044712 single-organism catabolic process; GO:0002446 neutrophil mediated immunity; GO:0016192 vesicle-mediated transport; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0009100 glycoprotein metabolic process; GO:0002376 immune system process; GO:0043312 neutrophil degranulation; GO:0044238 primary metabolic process; GO:0005975 carbohydrate metabolic process; GO:0002263 cell activation involved in immune response; GO:0002444 myeloid leukocyte mediated immunity; GO:0016052 carbohydrate catabolic process; GO:0006810 transport; GO:0002366 leukocyte activation involved in immune response; GO:0044723 single-organism carbohydrate metabolic process; GO:1901575 organic substance catabolic process; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:0032940 secretion by cell; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0001775 cell activation; GO:0006464 cellular protein modification process; GO:0043299 leukocyte degranulation; GO:0051179 localization; GO:0006955 immune response; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:0009056 catabolic process; GO:0006887 exocytosis; GO:0019318 hexose metabolic process; ","GO:0034774 secretory granule lumen; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0043202 lysosomal lumen; GO:0005576 extracellular region; GO:0042582 azurophil granule; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0015923 mannosidase activity; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0004559 alpha-mannosidase activity; GO:0016798 hydrolase activity, acting on glycosyl bonds; GO:0030246 carbohydrate binding; GO:0043169 cation binding; GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds; GO:0046872 metal ion binding; GO:0016787 hydrolase activity; GO:0008270 zinc ion binding; ","K12311","MAN2B1; lysosomal alpha-mannosidase [EC:3.2.1.24]","hsa04142 Lysosome - Homo sapiens (human); hsa00511 Other glycan degradation - Homo sapiens (human); ","IPR027291; IPR028995; IPR011682; IPR000602; IPR015341; IPR011013; IPR011330; IPR013780; ","\"Glycoside hydrolase 38/57, N-terminal domain; Glycoside hydrolase families 57/38, central domain; Glycosyl hydrolase family 38, C-terminal; Glycoside hydrolase family 38, N-terminal domain; Glycoside hydrolase family 38, central domain; Galactose mutarotase-like domain; Glycoside hydrolase/deacetylase, beta/alpha-barrel; Glycosyl hydrolase, all-beta; \"\r"]
["O00764","Pyridoxal kinase OS=Homo sapiens OX=9606 GN=PDXK","PDXK",35.102,17.515,12.2,5,8,5,1.207,1.403,1.335,0.728,0.707,0.67,0.534,2.41E-4,"cytoplasm\r","GO:0051188 cofactor biosynthetic process; GO:0045321 leukocyte activation; GO:0042822 pyridoxal phosphate metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0072524 pyridine-containing compound metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0072525 pyridine-containing compound biosynthetic process; GO:0008152 metabolic process; GO:0009108 coenzyme biosynthetic process; GO:0042823 pyridoxal phosphate biosynthetic process; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0002443 leukocyte mediated immunity; GO:0018130 heterocycle biosynthetic process; GO:0009443 pyridoxal 5'-phosphate salvage; GO:0002446 neutrophil mediated immunity; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006081 cellular aldehyde metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0006732 coenzyme metabolic process; GO:1901617 organic hydroxy compound biosynthetic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0051186 cofactor metabolic process; GO:0006810 transport; GO:0090407 organophosphate biosynthetic process; GO:0032940 secretion by cell; GO:0043094 cellular metabolic compound salvage; GO:0044710 single-organism metabolic process; GO:0043299 leukocyte degranulation; GO:1901362 organic cyclic compound biosynthetic process; GO:0016310 phosphorylation; GO:0002283 neutrophil activation involved in immune response; GO:1901615 organic hydroxy compound metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0002252 immune effector process; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0006766 vitamin metabolic process; GO:0046483 heterocycle metabolic process; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0019438 aromatic compound biosynthetic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0046184 aldehyde biosynthetic process; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0006767 water-soluble vitamin metabolic process; GO:0042816 vitamin B6 metabolic process; GO:0044711 single-organism biosynthetic process; GO:0016192 vesicle-mediated transport; GO:0006807 nitrogen compound metabolic process; GO:0008283 cell proliferation; GO:0002376 immune system process; GO:0043312 neutrophil degranulation; GO:1901576 organic substance biosynthetic process; GO:0002263 cell activation involved in immune response; GO:0044249 cellular biosynthetic process; GO:0002366 leukocyte activation involved in immune response; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0001775 cell activation; GO:0019637 organophosphate metabolic process; GO:0051179 localization; GO:0006955 immune response; GO:0006887 exocytosis; GO:1901564 organonitrogen compound metabolic process; ","GO:0034774 secretory granule lumen; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0035580 specific granule lumen; GO:0042581 specific granule; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0008478 pyridoxal kinase activity; GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0031402 sodium ion binding; GO:0046983 protein dimerization activity; GO:0030955 potassium ion binding; GO:0005515 protein binding; GO:0030170 pyridoxal phosphate binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0042802 identical protein binding; GO:0016301 kinase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0031420 alkali metal ion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0000287 magnesium ion binding; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0008270 zinc ion binding; GO:0048037 cofactor binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0046914 transition metal ion binding; GO:0031403 lithium ion binding; GO:0042803 protein homodimerization activity; GO:0046872 metal ion binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0036094 small molecule binding; ","K00868","pdxK; pyridoxine kinase [EC:2.7.1.35]","hsa00750 Vitamin B6 metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR013749; IPR029056; ","Pyridoxamine kinase/Phosphomethylpyrimidine kinase; Ribokinase-like; \r"]
["O14498","Immunoglobulin superfamily containing leucine-rich repeat protein OS=Homo sapiens OX=9606 GN=ISLR","ISLR",45.997,15.113,8.6,3,4,3,0.984,1.127,1.016,1.031,0.931,0.929,0.925,0.218,"extracellular\r","GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0002576 platelet degranulation; GO:0044699 single-organism process; GO:0051234 establishment of localization; GO:0006810 transport; GO:0022610 biological adhesion; GO:0045055 regulated exocytosis; GO:1902578 single-organism localization; GO:0032940 secretion by cell; GO:0007155 cell adhesion; GO:0051179 localization; GO:0009987 cellular process; GO:0006887 exocytosis; GO:0046903 secretion; GO:0044765 single-organism transport; ","GO:0034774 secretory granule lumen; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0043226 organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0031093 platelet alpha granule lumen; GO:0031091 platelet alpha granule; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR003598; IPR007110; IPR000483; IPR013783; IPR032675; IPR013098; ","\"Immunoglobulin subtype 2; Immunoglobulin-like domain; Cysteine-rich flanking region, C-terminal; Immunoglobulin-like fold; Leucine-rich repeat domain, L domain-like; Immunoglobulin I-set; \"\r"]
["O14524","Nuclear envelope integral membrane protein 1 OS=Homo sapiens OX=9606 GN=NEMP1","NEMP1",50.639,1.73,1.6,1,1,1,1.015,0.997,1.146,1,0.917,0.938,0.904,0.122,"plasma membrane\r",null,"GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0031090 organelle membrane; GO:0005635 nuclear envelope; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031965 nuclear membrane; GO:0005634 nucleus; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0031975 envelope; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005637 nuclear inner membrane; GO:0044428 nuclear part; "]
["O14545","TRAF-type zinc finger domain-containing protein 1 OS=Homo sapiens OX=9606 GN=TRAFD1","TRAFD1",64.84,9.3602,5.3,3,4,3,0.861,0.862,0.959,1.059,0.9,1.072,1.13,0.145,"nucleus\r","GO:0045824 negative regulation of innate immune response; GO:0002683 negative regulation of immune system process; GO:0050789 regulation of biological process; GO:0045088 regulation of innate immune response; GO:0048583 regulation of response to stimulus; GO:0050777 negative regulation of immune response; GO:0002682 regulation of immune system process; GO:0080134 regulation of response to stress; GO:0048519 negative regulation of biological process; GO:0048585 negative regulation of response to stimulus; GO:0031347 regulation of defense response; GO:0031348 negative regulation of defense response; GO:0065007 biological regulation; GO:0050776 regulation of immune response; ",null,"GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0005488 binding; GO:0043167 ion binding; "]
["O14548","Cytochrome c oxidase subunit 7A-related protein, mitochondrial OS=Homo sapiens OX=9606 GN=COX7A2L","COX7A2L",12.615,3.2425,14.9,2,3,2,1.036,0.792,0.889,1.03,1.056,1.191,1.206,0.0999,"cytoplasm\r","GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0006123 mitochondrial electron transport, cytochrome c to oxygen; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0006753 nucleoside phosphate metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0044765 single-organism transport; GO:0098655 cation transmembrane transport; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006119 oxidative phosphorylation; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0006810 transport; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0022900 electron transport chain; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0098662 inorganic cation transmembrane transport; GO:0016310 phosphorylation; GO:0034220 ion transmembrane transport; GO:0006725 cellular aromatic compound metabolic process; GO:0042773 ATP synthesis coupled electron transport; GO:0009259 ribonucleotide metabolic process; GO:0022904 respiratory electron transport chain; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:1902578 single-organism localization; GO:0006139 nucleobase-containing compound metabolic process; GO:0006812 cation transport; GO:1902600 hydrogen ion transmembrane transport; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009119 ribonucleoside metabolic process; GO:0009987 cellular process; GO:0046034 ATP metabolic process; GO:0098660 inorganic ion transmembrane transport; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0045333 cellular respiration; GO:0006163 purine nucleotide metabolic process; GO:0006818 hydrogen transport; GO:0015992 proton transport; GO:0046128 purine ribonucleoside metabolic process; GO:0055085 transmembrane transport; GO:0006793 phosphorus metabolic process; GO:0006811 ion transport; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0051179 localization; GO:0015672 monovalent inorganic cation transport; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005739 mitochondrion; GO:0005746 mitochondrial respiratory chain; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0031975 envelope; GO:0070469 respiratory chain; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0015075 ion transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0015077 monovalent inorganic cation transmembrane transporter activity; GO:0016676 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor; GO:0016675 oxidoreductase activity, acting on a heme group of donors; GO:0015078 hydrogen ion transmembrane transporter activity; GO:0015002 heme-copper terminal oxidase activity; GO:0016491 oxidoreductase activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0009055 electron carrier activity; GO:0004129 cytochrome-c oxidase activity; GO:0003824 catalytic activity; GO:0022890 inorganic cation transmembrane transporter activity; GO:0008324 cation transmembrane transporter activity; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; ","K02270","COX7A; cytochrome c oxidase subunit 7a","hsa04260 Cardiac muscle contraction - Homo sapiens (human); hsa05010 Alzheimer's disease - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); "]
["O14558","Heat shock protein beta-6 OS=Homo sapiens OX=9606 GN=HSPB6","HSPB6",17.135,15.664,29.4,4,10,4,1.14,1.156,1.034,0.991,0.719,0.888,0.78,0.0636,"cyto_nucl\r","GO:0050794 regulation of cellular process; GO:0010667 negative regulation of cardiac muscle cell apoptotic process; GO:0010941 regulation of cell death; GO:0043069 negative regulation of programmed cell death; GO:0061077 chaperone-mediated protein folding; GO:0043067 regulation of programmed cell death; GO:0048519 negative regulation of biological process; GO:0010665 regulation of cardiac muscle cell apoptotic process; GO:0048523 negative regulation of cellular process; GO:0045766 positive regulation of angiogenesis; GO:0051239 regulation of multicellular organismal process; GO:0006457 protein folding; GO:0051240 positive regulation of multicellular organismal process; GO:0043066 negative regulation of apoptotic process; GO:1904018 positive regulation of vasculature development; GO:0044057 regulation of system process; GO:0009987 cellular process; GO:0010664 negative regulation of striated muscle cell apoptotic process; GO:0006937 regulation of muscle contraction; GO:1901342 regulation of vasculature development; GO:0090257 regulation of muscle system process; GO:0048518 positive regulation of biological process; GO:0010656 negative regulation of muscle cell apoptotic process; GO:0010660 regulation of muscle cell apoptotic process; GO:0050789 regulation of biological process; GO:0010662 regulation of striated muscle cell apoptotic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0045765 regulation of angiogenesis; GO:0050793 regulation of developmental process; GO:0060548 negative regulation of cell death; GO:0051094 positive regulation of developmental process; GO:0042981 regulation of apoptotic process; GO:2000026 regulation of multicellular organismal development; GO:0065007 biological regulation; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0005576 extracellular region; ","GO:0005212 structural constituent of eye lens; GO:0042802 identical protein binding; GO:0051087 chaperone binding; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:0051082 unfolded protein binding; GO:0005198 structural molecule activity; ","K09545",null,null,"IPR002068; IPR003090; IPR008978; ","\"Alpha crystallin/Hsp20 domain; Alpha-crystallin, N-terminal; HSP20-like chaperone; \"\r"]
["O14561","Acyl carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFAB1","NDUFAB1",17.417,15.226,15.4,3,7,3,0.981,0.989,0.996,1.011,0.987,1.007,1.013,0.206,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:0009116 nucleoside metabolic process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0008610 lipid biosynthetic process; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0006091 generation of precursor metabolites and energy; GO:0065003 macromolecular complex assembly; GO:0030258 lipid modification; GO:0019693 ribose phosphate metabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0046487 glyoxylate metabolic process; GO:0010257 NADH dehydrogenase complex assembly; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006081 cellular aldehyde metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0072329 monocarboxylic acid catabolic process; GO:0005975 carbohydrate metabolic process; GO:0046493 lipid A metabolic process; GO:0090407 organophosphate biosynthetic process; GO:0046395 carboxylic acid catabolic process; GO:1901269 lipooligosaccharide metabolic process; GO:1901575 organic substance catabolic process; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0022900 electron transport chain; GO:0006464 cellular protein modification process; GO:0009126 purine nucleoside monophosphate metabolic process; GO:0009062 fatty acid catabolic process; GO:0043436 oxoacid metabolic process; GO:0016310 phosphorylation; GO:0009259 ribonucleotide metabolic process; GO:0044267 cellular protein metabolic process; GO:0009249 protein lipoylation; GO:0018065 protein-cofactor linkage; GO:0032981 mitochondrial respiratory chain complex I assembly; GO:0046483 heterocycle metabolic process; GO:1901271 lipooligosaccharide biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0044248 cellular catabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0009119 ribonucleoside metabolic process; GO:0006461 protein complex assembly; GO:0016042 lipid catabolic process; GO:0044711 single-organism biosynthetic process; GO:0006635 fatty acid beta-oxidation; GO:0009141 nucleoside triphosphate metabolic process; GO:0009312 oligosaccharide biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0006163 purine nucleotide metabolic process; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0044283 small molecule biosynthetic process; GO:0016054 organic acid catabolic process; GO:0019637 organophosphate metabolic process; GO:0044242 cellular lipid catabolic process; GO:0006644 phospholipid metabolic process; GO:0043412 macromolecule modification; GO:0072330 monocarboxylic acid biosynthetic process; GO:1901564 organonitrogen compound metabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0016053 organic acid biosynthetic process; GO:0006643 membrane lipid metabolic process; GO:0009117 nucleotide metabolic process; GO:0008654 phospholipid biosynthetic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0006796 phosphate-containing compound metabolic process; GO:0022607 cellular component assembly; GO:0006753 nucleoside phosphate metabolic process; GO:0007005 mitochondrion organization; GO:0006629 lipid metabolic process; GO:0019395 fatty acid oxidation; GO:0071822 protein complex subunit organization; GO:0055114 oxidation-reduction process; GO:0006119 oxidative phosphorylation; GO:0006664 glycolipid metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0006120 mitochondrial electron transport, NADH to ubiquinone; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0006633 fatty acid biosynthetic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0046394 carboxylic acid biosynthetic process; GO:0097031 mitochondrial respiratory chain complex I biogenesis; GO:0009245 lipid A biosynthetic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:1901657 glycosyl compound metabolic process; GO:0006082 organic acid metabolic process; GO:0036211 protein modification process; GO:0070271 protein complex biogenesis; GO:0033108 mitochondrial respiratory chain complex assembly; GO:0034440 lipid oxidation; GO:0016043 cellular component organization; GO:0009247 glycolipid biosynthetic process; GO:0016051 carbohydrate biosynthetic process; GO:1903509 liposaccharide metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0042773 ATP synthesis coupled electron transport; GO:0022904 respiratory electron transport chain; GO:0071704 organic substance metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009311 oligosaccharide metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0009987 cellular process; GO:0046467 membrane lipid biosynthetic process; GO:0043623 cellular protein complex assembly; GO:0046034 ATP metabolic process; GO:0034622 cellular macromolecular complex assembly; GO:0044712 single-organism catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044282 small molecule catabolic process; GO:0006631 fatty acid metabolic process; GO:0045333 cellular respiration; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0046128 purine ribonucleoside metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0009056 catabolic process; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0045271 respiratory chain complex I; GO:0032991 macromolecular complex; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0005747 mitochondrial respiratory chain complex I; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0098803 respiratory chain complex; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005759 mitochondrial matrix; GO:0044429 mitochondrial part; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005739 mitochondrion; GO:0005746 mitochondrial respiratory chain; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0030964 NADH dehydrogenase complex; GO:0031975 envelope; GO:1990204 oxidoreductase complex; GO:0043234 protein complex; GO:0031966 mitochondrial membrane; GO:0070469 respiratory chain; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:0031177 phosphopantetheine binding; GO:0019842 vitamin binding; GO:0043167 ion binding; GO:0043177 organic acid binding; GO:0050136 NADH dehydrogenase (quinone) activity; GO:0044620 ACP phosphopantetheine attachment site binding; GO:0005515 protein binding; GO:0033218 amide binding; GO:0033293 monocarboxylic acid binding; GO:0048037 cofactor binding; GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; GO:0008137 NADH dehydrogenase (ubiquinone) activity; GO:0016491 oxidoreductase activity; GO:0000035 acyl binding; GO:0003954 NADH dehydrogenase activity; GO:0031406 carboxylic acid binding; GO:0072341 modified amino acid binding; GO:0051192 prosthetic group binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0008289 lipid binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0043168 anion binding; GO:0005509 calcium ion binding; GO:0005504 fatty acid binding; GO:0000036 ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process; GO:0036094 small molecule binding; ","K03955","NDUFAB1; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1","hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); ","IPR009081; ","Phosphopantetheine binding ACP domain; \r"]
["O14579","Coatomer subunit epsilon OS=Homo sapiens OX=9606 GN=COPE","COPE",34.482,13.778,12,3,4,3,0.87,0.875,0.894,1.19,1.141,1.026,1.272,0.006,"cytoplasm\r","GO:0046907 intracellular transport; GO:0006891 intra-Golgi vesicle-mediated transport; GO:0016192 vesicle-mediated transport; GO:0048193 Golgi vesicle transport; GO:0071702 organic substance transport; GO:0015031 protein transport; GO:0051641 cellular localization; GO:0051234 establishment of localization; GO:0006810 transport; GO:0045184 establishment of protein localization; GO:0051649 establishment of localization in cell; GO:0006890 retrograde vesicle-mediated transport, Golgi to ER; GO:0051179 localization; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0006888 ER to Golgi vesicle-mediated transport; ","GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0098796 membrane protein complex; GO:0030137 COPI-coated vesicle; GO:0030660 Golgi-associated vesicle membrane; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0030120 vesicle coat; GO:0030663 COPI-coated vesicle membrane; GO:0005623 cell; GO:0030662 coated vesicle membrane; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0030126 COPI vesicle coat; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0044431 Golgi apparatus part; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0048475 coated membrane; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0005829 cytosol; GO:0030135 coated vesicle; GO:0005798 Golgi-associated vesicle; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044432 endoplasmic reticulum part; GO:0030117 membrane coat; GO:0030133 transport vesicle; GO:0043234 protein complex; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0005198 structural molecule activity; GO:0005488 binding; ","K17268",null,null,"IPR011990; ","Tetratricopeptide-like helical domain; \r"]
["O14617","AP-3 complex subunit delta-1 OS=Homo sapiens OX=9606 GN=AP3D1","AP3D1",130.16,17.832,4.6,5,5,5,0.972,0.967,0.87,1.097,1.006,0.994,1.103,0.109,"cytoplasm\r","GO:0002694 regulation of leukocyte activation; GO:0021700 developmental maturation; GO:0065008 regulation of biological quality; GO:0015031 protein transport; GO:0009605 response to external stimulus; GO:0099003 vesicle-mediated transport in synapse; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0099517 synaptic vesicle transport along microtubule; GO:0033365 protein localization to organelle; GO:0045621 positive regulation of lymphocyte differentiation; GO:0008104 protein localization; GO:0008089 anterograde axonal transport; GO:0044765 single-organism transport; GO:0016182 synaptic vesicle budding from endosome; GO:0051716 cellular response to stimulus; GO:0061462 protein localization to lysosome; GO:0048489 synaptic vesicle transport; GO:0072657 protein localization to membrane; GO:0044763 single-organism cellular process; GO:0072665 protein localization to vacuole; GO:0006810 transport; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0048499 synaptic vesicle membrane organization; GO:0044710 single-organism metabolic process; GO:0048069 eye pigmentation; GO:0046634 regulation of alpha-beta T cell activation; GO:0002682 regulation of immune system process; GO:0051094 positive regulation of developmental process; GO:0051640 organelle localization; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0099514 synaptic vesicle cytoskeletal transport; GO:0045580 regulation of T cell differentiation; GO:0032844 regulation of homeostatic process; GO:0051239 regulation of multicellular organismal process; GO:0045597 positive regulation of cell differentiation; GO:0099532 synaptic vesicle endosomal processing; GO:0030705 cytoskeleton-dependent intracellular transport; GO:0099637 neurotransmitter receptor transport; GO:1903706 regulation of hemopoiesis; GO:0050867 positive regulation of cell activation; GO:1902578 single-organism localization; GO:0002475 antigen processing and presentation via MHC class Ib; GO:0061088 regulation of sequestering of zinc ion; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:1902580 single-organism cellular localization; GO:0006726 eye pigment biosynthetic process; GO:0034613 cellular protein localization; GO:0036465 synaptic vesicle recycling; GO:0045785 positive regulation of cell adhesion; GO:0036466 synaptic vesicle recycling via endosome; GO:0098930 axonal transport; GO:0016192 vesicle-mediated transport; GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib; GO:0002376 immune system process; GO:0071702 organic substance transport; GO:0045582 positive regulation of T cell differentiation; GO:0051656 establishment of organelle localization; GO:1903039 positive regulation of leukocyte cell-cell adhesion; GO:0007017 microtubule-based process; GO:0030155 regulation of cell adhesion; GO:0097480 establishment of synaptic vesicle localization; GO:0045184 establishment of protein localization; GO:0002696 positive regulation of leukocyte activation; GO:0050870 positive regulation of T cell activation; GO:0006996 organelle organization; GO:0097479 synaptic vesicle localization; GO:0006900 membrane budding; GO:0061024 membrane organization; GO:0006928 movement of cell or subcellular component; GO:0043473 pigmentation; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0033059 cellular pigmentation; GO:0043482 cellular pigment accumulation; GO:0050863 regulation of T cell activation; GO:0046148 pigment biosynthetic process; GO:0010256 endomembrane system organization; GO:0072594 establishment of protein localization to organelle; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0051249 regulation of lymphocyte activation; GO:0099504 synaptic vesicle cycle; GO:0046635 positive regulation of alpha-beta T cell activation; GO:0051234 establishment of localization; GO:0010970 transport along microtubule; GO:1902107 positive regulation of leukocyte differentiation; GO:0051649 establishment of localization in cell; GO:0072666 establishment of protein localization to vacuole; GO:0042441 eye pigment metabolic process; GO:0033036 macromolecule localization; GO:0043324 pigment metabolic process involved in developmental pigmentation; GO:0032438 melanosome organization; GO:0032502 developmental process; GO:0051650 establishment of vesicle localization; GO:0043476 pigment accumulation; GO:0048007 antigen processing and presentation, exogenous lipid antigen via MHC class Ib; GO:0048757 pigment granule maturation; GO:0048522 positive regulation of cellular process; GO:0051251 positive regulation of lymphocyte activation; GO:1902582 single-organism intracellular transport; GO:0016197 endosomal transport; GO:0008088 axo-dendritic transport; GO:0099518 vesicle cytoskeletal trafficking; GO:0050865 regulation of cell activation; GO:0050789 regulation of biological process; GO:1902105 regulation of leukocyte differentiation; GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome; GO:2000026 regulation of multicellular organismal development; GO:0072384 organelle transport along microtubule; GO:0016043 cellular component organization; GO:2000021 regulation of ion homeostasis; GO:0043485 endosome to pigment granule transport; GO:0048066 developmental pigmentation; GO:0048490 anterograde synaptic vesicle transport; GO:0050931 pigment cell differentiation; GO:0050896 response to stimulus; GO:0099111 microtubule-based transport; GO:0051136 regulation of NK T cell differentiation; GO:0030154 cell differentiation; GO:0051648 vesicle localization; GO:0006886 intracellular protein transport; GO:0043474 pigment metabolic process involved in pigmentation; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0007041 lysosomal transport; GO:1903708 positive regulation of hemopoiesis; GO:0048753 pigment granule organization; GO:0042440 pigment metabolic process; GO:0046637 regulation of alpha-beta T cell differentiation; GO:0022409 positive regulation of cell-cell adhesion; GO:0016050 vesicle organization; GO:0044802 single-organism membrane organization; GO:0048518 positive regulation of biological process; GO:0022407 regulation of cell-cell adhesion; GO:0035646 endosome to melanosome transport; GO:0045619 regulation of lymphocyte differentiation; GO:0051641 cellular localization; GO:0047496 vesicle transport along microtubule; GO:0007018 microtubule-based movement; GO:0070142 synaptic vesicle budding; GO:0019882 antigen processing and presentation; GO:0070727 cellular macromolecule localization; GO:0007034 vacuolar transport; GO:0046638 positive regulation of alpha-beta T cell differentiation; GO:0044767 single-organism developmental process; GO:0002684 positive regulation of immune system process; GO:0051138 positive regulation of NK T cell differentiation; GO:0032456 endocytic recycling; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0030119 AP-type membrane coat adaptor complex; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0098796 membrane protein complex; GO:0098830 presynaptic endosome; GO:0099568 cytoplasmic region; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0032838 cell projection cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0043679 axon terminus; GO:0044422 organelle part; GO:0030123 AP-3 adaptor complex; GO:0005765 lysosomal membrane; GO:0044425 membrane part; GO:0098793 presynapse; GO:0044464 cell part; GO:0005622 intracellular; GO:0098805 whole membrane; GO:0005764 lysosome; GO:0043005 neuron projection; GO:0044431 Golgi apparatus part; GO:0005768 endosome; GO:0044306 neuron projection terminus; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0044456 synapse part; GO:0000323 lytic vacuole; GO:0010008 endosome membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0042995 cell projection; GO:0098588 bounding membrane of organelle; GO:0048475 coated membrane; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0044440 endosomal part; GO:0012505 endomembrane system; GO:0044463 cell projection part; GO:0033267 axon part; GO:0045202 synapse; GO:0098852 lytic vacuole membrane; GO:0030424 axon; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:1904115 axon cytoplasm; GO:0044437 vacuolar part; GO:0043195 terminal bouton; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0030117 membrane coat; GO:0005794 Golgi apparatus; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0005488 binding; GO:0005215 transporter activity; ","K12396","AP3D; AP-3 complex subunit delta","hsa04142 Lysosome - Homo sapiens (human); ","IPR011989; IPR016024; IPR002553; ","\"Armadillo-like helical; Armadillo-type fold; Clathrin/coatomer adaptor, adaptin-like, N-terminal; \"\r"]
["O14639","Actin-binding LIM protein 1 OS=Homo sapiens OX=9606 GN=ABLIM1","ABLIM1",87.687,20.821,10.9,8,11,8,0.935,0.973,1.004,1.087,0.959,1.056,1.065,0.223,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0097581 lamellipodium organization; GO:0007601 visual perception; GO:0060271 cilium assembly; GO:0044699 single-organism process; GO:0044782 cilium organization; GO:0050877 neurological system process; GO:0009653 anatomical structure morphogenesis; GO:0070925 organelle assembly; GO:0022607 cellular component assembly; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0030032 lamellipodium assembly; GO:0032502 developmental process; GO:0007600 sensory perception; GO:0003008 system process; GO:0048731 system development; GO:0044763 single-organism cellular process; GO:0050953 sensory perception of light stimulus; GO:0032501 multicellular organismal process; GO:0030031 cell projection assembly; GO:1902589 single-organism organelle organization; GO:0048513 animal organ development; GO:0030030 cell projection organization; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0009887 animal organ morphogenesis; GO:0048856 anatomical structure development; GO:0071840 cellular component organization or biogenesis; ","GO:0031252 cell leading edge; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0097517 contractile actin filament bundle; GO:0044424 intracellular part; GO:0005623 cell; GO:0015629 actin cytoskeleton; GO:0044422 organelle part; GO:0032432 actin filament bundle; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0005856 cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0030027 lamellipodium; GO:0001725 stress fiber; GO:0042641 actomyosin; ","GO:0008092 cytoskeletal protein binding; GO:0046914 transition metal ion binding; GO:0005488 binding; GO:0043167 ion binding; GO:0003779 actin binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0008270 zinc ion binding; ","K07520","ABLIM; actin-binding LIM protein","hsa04360 Axon guidance - Homo sapiens (human); ","IPR001781; IPR003128; IPR032402; ","\"Zinc finger, LIM-type; Villin headpiece; Putative adherens-junction anchoring domain; \"\r"]
["O14683","Tumor protein p53-inducible protein 11 OS=Homo sapiens OX=9606 GN=TP53I11","TP53I11",21.054,2.3163,5.3,1,2,1,1.087,1.106,0.985,0.965,0.933,0.943,0.894,0.0414,"plasma membrane\r","GO:0050794 regulation of cellular process; GO:0050789 regulation of biological process; GO:0042127 regulation of cell proliferation; GO:0006950 response to stress; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:0065007 biological regulation; GO:0008285 negative regulation of cell proliferation; ","GO:0031224 intrinsic component of membrane; GO:0016020 membrane; GO:0016021 integral component of membrane; GO:0044425 membrane part; "]
["O14684","Prostaglandin E synthase OS=Homo sapiens OX=9606 GN=PTGES","PTGES",17.102,5.102,16.4,3,3,3,0.974,1.014,1.086,0.952,0.966,1.016,0.954,0.286,"extracellular\r","GO:0044700 single organism signaling; GO:0001101 response to acid chemical; GO:0016053 organic acid biosynthetic process; GO:1901568 fatty acid derivative metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0008285 negative regulation of cell proliferation; GO:0009607 response to biotic stimulus; GO:0008610 lipid biosynthetic process; GO:0009605 response to external stimulus; GO:0007165 signal transduction; GO:0046456 icosanoid biosynthetic process; GO:0008152 metabolic process; GO:0007154 cell communication; GO:0032787 monocarboxylic acid metabolic process; GO:0002544 chronic inflammatory response; GO:0010035 response to inorganic substance; GO:0006690 icosanoid metabolic process; GO:0006629 lipid metabolic process; GO:0051716 cellular response to stimulus; GO:0014070 response to organic cyclic compound; GO:0034097 response to cytokine; GO:0002237 response to molecule of bacterial origin; GO:0046457 prostanoid biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006636 unsaturated fatty acid biosynthetic process; GO:0023052 signaling; GO:0006633 fatty acid biosynthetic process; GO:0010038 response to metal ion; GO:0051704 multi-organism process; GO:0046394 carboxylic acid biosynthetic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0002526 acute inflammatory response; GO:0032526 response to retinoic acid; GO:0044710 single-organism metabolic process; GO:0006954 inflammatory response; GO:0006693 prostaglandin metabolic process; GO:0006952 defense response; GO:0006082 organic acid metabolic process; GO:0043436 oxoacid metabolic process; GO:0033559 unsaturated fatty acid metabolic process; GO:0019371 cyclooxygenase pathway; GO:0050794 regulation of cellular process; GO:0019369 arachidonic acid metabolic process; GO:0042127 regulation of cell proliferation; GO:1901700 response to oxygen-containing compound; GO:0043207 response to external biotic stimulus; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0001516 prostaglandin biosynthetic process; GO:0071704 organic substance metabolic process; GO:0033993 response to lipid; GO:0051592 response to calcium ion; GO:0009987 cellular process; GO:0009617 response to bacterium; GO:0006950 response to stress; GO:0044711 single-organism biosynthetic process; GO:0032496 response to lipopolysaccharide; GO:0006692 prostanoid metabolic process; GO:1901570 fatty acid derivative biosynthetic process; GO:0006631 fatty acid metabolic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0001676 long-chain fatty acid metabolic process; GO:0044283 small molecule biosynthetic process; GO:0019752 carboxylic acid metabolic process; GO:0072330 monocarboxylic acid biosynthetic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005635 nuclear envelope; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0005737 cytoplasm; GO:0012505 endomembrane system; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0005641 nuclear envelope lumen; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0031970 organelle envelope lumen; GO:0044432 endoplasmic reticulum part; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0031975 envelope; GO:0048471 perinuclear region of cytoplasm; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0016853 isomerase activity; GO:0072341 modified amino acid binding; GO:0003824 catalytic activity; GO:0042277 peptide binding; GO:0005488 binding; GO:0043167 ion binding; GO:0043168 anion binding; GO:0016860 intramolecular oxidoreductase activity; GO:0043295 glutathione binding; GO:0033218 amide binding; GO:1900750 oligopeptide binding; GO:1901681 sulfur compound binding; GO:0050220 prostaglandin-E synthase activity; ","K15729","PTGES; microsomal prostaglandin-E synthase 1 [EC:5.3.99.3]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00590 Arachidonic acid metabolism - Homo sapiens (human); ","IPR023352; ","Membrane associated eicosanoid/glutathione metabolism-like domain; \r"]
["O14732","Inositol monophosphatase 2 OS=Homo sapiens OX=9606 GN=IMPA2","IMPA2",31.321,18.614,21.5,6,9,6,0.85,0.965,1.07,1.034,0.99,0.997,1.047,0.5,"cytoskeleton\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0016310 phosphorylation; GO:0016051 carbohydrate biosynthetic process; GO:0046486 glycerolipid metabolic process; GO:1901615 organic hydroxy compound metabolic process; GO:0046434 organophosphate catabolic process; GO:0006020 inositol metabolic process; GO:0006066 alcohol metabolic process; GO:0046854 phosphatidylinositol phosphorylation; GO:0006021 inositol biosynthetic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044255 cellular lipid metabolic process; GO:0046164 alcohol catabolic process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:1901616 organic hydroxy compound catabolic process; GO:0007154 cell communication; GO:0044262 cellular carbohydrate metabolic process; GO:0030258 lipid modification; GO:0006650 glycerophospholipid metabolic process; GO:0046855 inositol phosphate dephosphorylation; GO:0046488 phosphatidylinositol metabolic process; GO:0034637 cellular carbohydrate biosynthetic process; GO:0009987 cellular process; GO:0006629 lipid metabolic process; GO:0051716 cellular response to stimulus; GO:0044711 single-organism biosynthetic process; GO:0071545 inositol phosphate catabolic process; GO:0044712 single-organism catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0046165 alcohol biosynthetic process; GO:0044282 small molecule catabolic process; GO:1901617 organic hydroxy compound biosynthetic process; GO:0023052 signaling; GO:0005975 carbohydrate metabolic process; GO:0044238 primary metabolic process; GO:0016311 dephosphorylation; GO:1901576 organic substance biosynthetic process; GO:0019751 polyol metabolic process; GO:0044249 cellular biosynthetic process; GO:0046834 lipid phosphorylation; GO:1901575 organic substance catabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0050789 regulation of biological process; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0046838 phosphorylated carbohydrate dephosphorylation; GO:0044283 small molecule biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0043647 inositol phosphate metabolic process; GO:0046173 polyol biosynthetic process; GO:0006644 phospholipid metabolic process; GO:0009056 catabolic process; GO:0046174 polyol catabolic process; GO:0065007 biological regulation; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0044444 cytoplasmic part; ","GO:0016791 phosphatase activity; GO:0043167 ion binding; GO:0046983 protein dimerization activity; GO:0052833 inositol monophosphate 4-phosphatase activity; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0052832 inositol monophosphate 3-phosphatase activity; GO:0052745 inositol phosphate phosphatase activity; GO:0052834 inositol monophosphate phosphatase activity; GO:0042802 identical protein binding; GO:0042578 phosphoric ester hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0042803 protein homodimerization activity; GO:0016788 hydrolase activity, acting on ester bonds; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0008934 inositol monophosphate 1-phosphatase activity; ","K01092","E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]","hsa00562 Inositol phosphate metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa04070 Phosphatidylinositol signaling system - Homo sapiens (human); "]
["O14735","CDP-diacylglycerol--inositol 3-phosphatidyltransferase OS=Homo sapiens OX=9606 GN=CDIPT","CDIPT",23.539,5.6567,9.9,2,2,2,1.149,1.163,0.986,0.917,0.86,0.95,0.827,0.036,"plasma membrane\r","GO:0046486 glycerolipid metabolic process; GO:0044711 single-organism biosynthetic process; GO:0006661 phosphatidylinositol biosynthetic process; GO:0008654 phospholipid biosynthetic process; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044255 cellular lipid metabolic process; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:1901576 organic substance biosynthetic process; GO:0006796 phosphate-containing compound metabolic process; GO:0044249 cellular biosynthetic process; GO:0071704 organic substance metabolic process; GO:0008610 lipid biosynthetic process; GO:0045017 glycerolipid biosynthetic process; GO:0090407 organophosphate biosynthetic process; GO:0008152 metabolic process; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0046474 glycerophospholipid biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0006650 glycerophospholipid metabolic process; GO:0046488 phosphatidylinositol metabolic process; GO:0046341 CDP-diacylglycerol metabolic process; GO:0006644 phospholipid metabolic process; GO:0009987 cellular process; GO:0006629 lipid metabolic process; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0098588 bounding membrane of organelle; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0000139 Golgi membrane; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044432 endoplasmic reticulum part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0044431 Golgi apparatus part; GO:0005794 Golgi apparatus; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; ","GO:0043167 ion binding; GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity; GO:0005515 protein binding; GO:0016780 phosphotransferase activity, for other substituted phosphate groups; GO:0030145 manganese ion binding; GO:0046914 transition metal ion binding; GO:0017169 CDP-alcohol phosphatidyltransferase activity; GO:0003824 catalytic activity; GO:0019992 diacylglycerol binding; GO:0043178 alcohol binding; GO:0005488 binding; GO:0008289 lipid binding; GO:0030246 carbohydrate binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0016740 transferase activity; GO:0036094 small molecule binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K00999","CDIPT; CDP-diacylglycerol--inositol 3-phosphatidyltransferase [EC:2.7.8.11]","hsa00562 Inositol phosphate metabolism - Homo sapiens (human); hsa00564 Glycerophospholipid metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa04070 Phosphatidylinositol signaling system - Homo sapiens (human); "]
["O14737","Programmed cell death protein 5 OS=Homo sapiens OX=9606 GN=PDCD5","PDCD5",14.285,22.374,44,5,10,5,1.027,1.003,0.915,1.081,0.969,1.041,1.05,0.365,"cytoplasm\r","GO:0010941 regulation of cell death; GO:1903955 positive regulation of protein targeting to mitochondrion; GO:0032270 positive regulation of cellular protein metabolic process; GO:0090199 regulation of release of cytochrome c from mitochondria; GO:1903533 regulation of protein targeting; GO:0023051 regulation of signaling; GO:0071560 cellular response to transforming growth factor beta stimulus; GO:1903644 regulation of chaperone-mediated protein folding; GO:0044699 single-organism process; GO:0071363 cellular response to growth factor stimulus; GO:0010821 regulation of mitochondrion organization; GO:1903749 positive regulation of establishment of protein localization to mitochondrion; GO:0008285 negative regulation of cell proliferation; GO:0051130 positive regulation of cellular component organization; GO:2001233 regulation of apoptotic signaling pathway; GO:0010646 regulation of cell communication; GO:0009893 positive regulation of metabolic process; GO:0032879 regulation of localization; GO:1903747 regulation of establishment of protein localization to mitochondrion; GO:0006915 apoptotic process; GO:0044093 positive regulation of molecular function; GO:0009719 response to endogenous stimulus; GO:0070848 response to growth factor; GO:0070887 cellular response to chemical stimulus; GO:0052548 regulation of endopeptidase activity; GO:0010468 regulation of gene expression; GO:0051716 cellular response to stimulus; GO:1903636 regulation of protein import into mitochondrial outer membrane; GO:0010950 positive regulation of endopeptidase activity; GO:0080090 regulation of primary metabolic process; GO:2000116 regulation of cysteine-type endopeptidase activity; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0032386 regulation of intracellular transport; GO:0031323 regulation of cellular metabolic process; GO:0071559 response to transforming growth factor beta; GO:0051050 positive regulation of transport; GO:0010942 positive regulation of cell death; GO:0034762 regulation of transmembrane transport; GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0051336 regulation of hydrolase activity; GO:0010638 positive regulation of organelle organization; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:1903645 negative regulation of chaperone-mediated protein folding; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051223 regulation of protein transport; GO:0090200 positive regulation of release of cytochrome c from mitochondria; GO:0052547 regulation of peptidase activity; GO:1903638 positive regulation of protein import into mitochondrial outer membrane; GO:0051222 positive regulation of protein transport; GO:0010952 positive regulation of peptidase activity; GO:0043068 positive regulation of programmed cell death; GO:1903332 regulation of protein folding; GO:0050794 regulation of cellular process; GO:0034764 positive regulation of transmembrane transport; GO:0090316 positive regulation of intracellular protein transport; GO:0042127 regulation of cell proliferation; GO:2001056 positive regulation of cysteine-type endopeptidase activity; GO:1903829 positive regulation of cellular protein localization; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0043067 regulation of programmed cell death; GO:0043065 positive regulation of apoptotic process; GO:1904589 regulation of protein import; GO:1903333 negative regulation of protein folding; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:1905477 positive regulation of protein localization to membrane; GO:0070201 regulation of establishment of protein localization; GO:0060341 regulation of cellular localization; GO:1905475 regulation of protein localization to membrane; GO:0045862 positive regulation of proteolysis; GO:0051345 positive regulation of hydrolase activity; GO:0023056 positive regulation of signaling; GO:0010628 positive regulation of gene expression; GO:2001235 positive regulation of apoptotic signaling pathway; GO:0032880 regulation of protein localization; GO:0010647 positive regulation of cell communication; GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0033157 regulation of intracellular protein transport; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:0051049 regulation of transport; GO:0032388 positive regulation of intracellular transport; GO:0033043 regulation of organelle organization; GO:1903214 regulation of protein targeting to mitochondrion; GO:0010033 response to organic substance; GO:0030162 regulation of proteolysis; GO:0048518 positive regulation of biological process; GO:0010822 positive regulation of mitochondrion organization; GO:0043085 positive regulation of catalytic activity; GO:0051247 positive regulation of protein metabolic process; GO:1904951 positive regulation of establishment of protein localization; GO:0008219 cell death; GO:0071495 cellular response to endogenous stimulus; GO:0051246 regulation of protein metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0051128 regulation of cellular component organization; GO:0009967 positive regulation of signal transduction; GO:0012501 programmed cell death; GO:0048584 positive regulation of response to stimulus; GO:1903827 regulation of cellular protein localization; GO:1904591 positive regulation of protein import; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0003677 DNA binding; GO:0043167 ion binding; GO:0015631 tubulin binding; GO:0005515 protein binding; GO:0048487 beta-tubulin binding; GO:0098772 molecular function regulator; GO:0008201 heparin binding; GO:1901681 sulfur compound binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0010698 acetyltransferase activator activity; GO:0097367 carbohydrate derivative binding; GO:0008092 cytoskeletal protein binding; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0043168 anion binding; GO:0005539 glycosaminoglycan binding; GO:0008047 enzyme activator activity; ","K06875"]
["O14744","Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5","PRMT5",72.683,10.463,7.1,4,4,4,0.981,1.034,0.917,0.997,1.047,1.031,1.049,0.266,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0048732 gland development; GO:0022618 ribonucleoprotein complex assembly; GO:0035247 peptidyl-arginine omega-N-methylation; GO:0014013 regulation of gliogenesis; GO:0097659 nucleic acid-templated transcription; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0008213 protein alkylation; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0065003 macromolecular complex assembly; GO:0043985 histone H4-R3 methylation; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006396 RNA processing; GO:0007399 nervous system development; GO:0042325 regulation of phosphorylation; GO:0048713 regulation of oligodendrocyte differentiation; GO:0051174 regulation of phosphorus metabolic process; GO:0018130 heterocycle biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0007088 regulation of mitotic nuclear division; GO:0044763 single-organism cellular process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0007030 Golgi organization; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0034969 histone arginine methylation; GO:0016071 mRNA metabolic process; GO:0051094 positive regulation of developmental process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0007346 regulation of mitotic cell cycle; GO:0060161 positive regulation of dopamine receptor signaling pathway; GO:0016570 histone modification; GO:0031399 regulation of protein modification process; GO:0018216 peptidyl-arginine methylation; GO:0044267 cellular protein metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0044030 regulation of DNA methylation; GO:0045597 positive regulation of cell differentiation; GO:0051239 regulation of multicellular organismal process; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0070372 regulation of ERK1 and ERK2 cascade; GO:0046483 heterocycle metabolic process; GO:0006479 protein methylation; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0051171 regulation of nitrogen compound metabolic process; GO:0061008 hepaticobiliary system development; GO:0016569 covalent chromatin modification; GO:0007275 multicellular organism development; GO:0008380 RNA splicing; GO:0009966 regulation of signal transduction; GO:1902531 regulation of intracellular signal transduction; GO:1904992 positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway; GO:0048731 system development; GO:0051960 regulation of nervous system development; GO:0060284 regulation of cell development; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0008283 cell proliferation; GO:0044238 primary metabolic process; GO:0032922 circadian regulation of gene expression; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0045685 regulation of glial cell differentiation; GO:0009890 negative regulation of biosynthetic process; GO:0001889 liver development; GO:0051276 chromosome organization; GO:0006996 organelle organization; GO:0043414 macromolecule methylation; GO:0001775 cell activation; GO:0050769 positive regulation of neurogenesis; GO:0048584 positive regulation of response to stimulus; GO:0043412 macromolecule modification; GO:0050793 regulation of developmental process; GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine; GO:0000387 spliceosomal snRNP assembly; GO:0031100 animal organ regeneration; GO:0051093 negative regulation of developmental process; GO:0010256 endomembrane system organization; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0009058 biosynthetic process; GO:0051253 negative regulation of RNA metabolic process; GO:0018195 peptidyl-arginine modification; GO:0032259 methylation; GO:0006353 DNA-templated transcription, termination; GO:2001141 regulation of RNA biosynthetic process; GO:0051783 regulation of nuclear division; GO:0045687 positive regulation of glial cell differentiation; GO:0010646 regulation of cell communication; GO:0071826 ribonucleoprotein complex subunit organization; GO:0035246 peptidyl-arginine N-methylation; GO:0022607 cellular component assembly; GO:0045596 negative regulation of cell differentiation; GO:0010720 positive regulation of cell development; GO:0051726 regulation of cell cycle; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0051962 positive regulation of nervous system development; GO:0008277 regulation of G-protein coupled receptor protein signaling pathway; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0006397 mRNA processing; GO:0007623 circadian rhythm; GO:0016070 RNA metabolic process; GO:0060159 regulation of dopamine receptor signaling pathway; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0051052 regulation of DNA metabolic process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:1902679 negative regulation of RNA biosynthetic process; GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0006325 chromatin organization; GO:0042118 endothelial cell activation; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:1904990 regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway; GO:2000026 regulation of multicellular organismal development; GO:0016571 histone methylation; GO:0016043 cellular component organization; GO:0097421 liver regeneration; GO:0048714 positive regulation of oligodendrocyte differentiation; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0090161 Golgi ribbon formation; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0030154 cell differentiation; GO:0043408 regulation of MAPK cascade; GO:0023056 positive regulation of signaling; GO:1901796 regulation of signal transduction by p53 class mediator; GO:0034641 cellular nitrogen compound metabolic process; GO:0010647 positive regulation of cell communication; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0034622 cellular macromolecular complex assembly; GO:0006355 regulation of transcription, DNA-templated; GO:0001932 regulation of protein phosphorylation; GO:0033043 regulation of organelle organization; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0018193 peptidyl-amino acid modification; GO:0014015 positive regulation of gliogenesis; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0048511 rhythmic process; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0010467 gene expression; GO:0051128 regulation of cellular component organization; GO:0009967 positive regulation of signal transduction; GO:0031327 negative regulation of cellular biosynthetic process; GO:0031099 regeneration; GO:0050767 regulation of neurogenesis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0012505 endomembrane system; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0035097 histone methyltransferase complex; GO:0044424 intracellular part; GO:1990234 transferase complex; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0034708 methyltransferase complex; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0034709 methylosome; GO:0005622 intracellular; GO:0044464 cell part; GO:0005794 Golgi apparatus; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0008757 S-adenosylmethionine-dependent methyltransferase activity; GO:1901265 nucleoside phosphate binding; GO:0008168 methyltransferase activity; GO:0003690 double-stranded DNA binding; GO:0008327 methyl-CpG binding; GO:0016274 protein-arginine N-methyltransferase activity; GO:0046983 protein dimerization activity; GO:0044020 histone methyltransferase activity (H4-R3 specific); GO:0005515 protein binding; GO:0001047 core promoter binding; GO:0000975 regulatory region DNA binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0001046 core promoter sequence-specific DNA binding; GO:0008276 protein methyltransferase activity; GO:0042054 histone methyltransferase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0016740 transferase activity; GO:0035243 protein-arginine omega-N symmetric methyltransferase activity; GO:0003677 DNA binding; GO:0003714 transcription corepressor activity; GO:0046982 protein heterodimerization activity; GO:0000976 transcription regulatory region sequence-specific DNA binding; GO:0044877 macromolecular complex binding; GO:1990837 sequence-specific double-stranded DNA binding; GO:0016741 transferase activity, transferring one-carbon groups; GO:0000166 nucleotide binding; GO:0043565 sequence-specific DNA binding; GO:0003712 transcription cofactor activity; GO:0008469 histone-arginine N-methyltransferase activity; GO:0001067 regulatory region nucleic acid binding; GO:0016273 arginine N-methyltransferase activity; GO:0044212 transcription regulatory region DNA binding; GO:0003676 nucleic acid binding; GO:0008170 N-methyltransferase activity; GO:0000988 transcription factor activity, protein binding; GO:0043021 ribonucleoprotein complex binding; GO:0032403 protein complex binding; GO:0036094 small molecule binding; ","K02516","PRMT5; type II protein arginine methyltransferase [EC:2.1.1.320]","hsa03013 RNA transport - Homo sapiens (human); ","IPR029063; ","S-adenosyl-L-methionine-dependent methyltransferase; \r"]
["O14745","Na(+)/H(+) exchange regulatory cofactor NHE-RF1 OS=Homo sapiens OX=9606 GN=SLC9A3R1","SLC9A3R1",38.868,42.365,30.4,9,13,9,0.993,1.036,1.018,0.958,0.936,0.989,0.946,0.0513,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0048732 gland development; GO:0072502 cellular trivalent inorganic anion homeostasis; GO:0055062 phosphate ion homeostasis; GO:0090317 negative regulation of intracellular protein transport; GO:0030320 cellular monovalent inorganic anion homeostasis; GO:0034635 glutathione transport; GO:0035315 hair cell differentiation; GO:0009913 epidermal cell differentiation; GO:0015718 monocarboxylic acid transport; GO:0003096 renal sodium ion transport; GO:0065003 macromolecular complex assembly; GO:0008360 regulation of cell shape; GO:0032535 regulation of cellular component size; GO:0044057 regulation of system process; GO:0008544 epidermis development; GO:0009790 embryo development; GO:1900181 negative regulation of protein localization to nucleus; GO:0016055 Wnt signaling pathway; GO:0042886 amide transport; GO:0048598 embryonic morphogenesis; GO:0090596 sensory organ morphogenesis; GO:0051051 negative regulation of transport; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0002064 epithelial cell development; GO:0072505 divalent inorganic anion homeostasis; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0007212 dopamine receptor signaling pathway; GO:0044763 single-organism cellular process; GO:0019932 second-messenger-mediated signaling; GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway; GO:0051683 establishment of Golgi localization; GO:0006810 transport; GO:1902532 negative regulation of intracellular signal transduction; GO:0007267 cell-cell signaling; GO:0032416 negative regulation of sodium:proton antiporter activity; GO:0048583 regulation of response to stimulus; GO:0051223 regulation of protein transport; GO:0032412 regulation of ion transmembrane transporter activity; GO:0030855 epithelial cell differentiation; GO:0051640 organelle localization; GO:0044707 single-multicellular organism process; GO:0002009 morphogenesis of an epithelium; GO:0002028 regulation of sodium ion transport; GO:0030001 metal ion transport; GO:0072506 trivalent inorganic anion homeostasis; GO:0097291 renal phosphate ion absorption; GO:0048519 negative regulation of biological process; GO:2000650 negative regulation of sodium ion transmembrane transporter activity; GO:0051898 negative regulation of protein kinase B signaling; GO:0009653 anatomical structure morphogenesis; GO:0072501 cellular divalent inorganic anion homeostasis; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:2000145 regulation of cell motility; GO:0010959 regulation of metal ion transport; GO:0035414 negative regulation of catenin import into nucleus; GO:1902580 single-organism cellular localization; GO:0061245 establishment or maintenance of bipolar cell polarity; GO:0034613 cellular protein localization; GO:0090150 establishment of protein localization to membrane; GO:0048878 chemical homeostasis; GO:0032409 regulation of transporter activity; GO:0034763 negative regulation of transmembrane transport; GO:0072348 sulfur compound transport; GO:0060088 auditory receptor cell stereocilium organization; GO:0051270 regulation of cellular component movement; GO:0003014 renal system process; GO:0044062 regulation of excretion; GO:0010876 lipid localization; GO:0055083 monovalent inorganic anion homeostasis; GO:0048839 inner ear development; GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway; GO:0060117 auditory receptor cell development; GO:0015849 organic acid transport; GO:0034766 negative regulation of ion transmembrane transport; GO:0007186 G-protein coupled receptor signaling pathway; GO:0072659 protein localization to plasma membrane; GO:0030336 negative regulation of cell migration; GO:0006996 organelle organization; GO:0007423 sensory organ development; GO:1903827 regulation of cellular protein localization; GO:0045936 negative regulation of phosphate metabolic process; GO:0046717 acid secretion; GO:0015850 organic hydroxy compound transport; GO:0010256 endomembrane system organization; GO:0060113 inner ear receptor cell differentiation; GO:0009968 negative regulation of signal transduction; GO:0061162 establishment of monopolar cell polarity; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:0051046 regulation of secretion; GO:0044699 single-organism process; GO:0042472 inner ear morphogenesis; GO:0031400 negative regulation of protein modification process; GO:0040013 negative regulation of locomotion; GO:0035412 regulation of catenin import into nucleus; GO:0042306 regulation of protein import into nucleus; GO:0048729 tissue morphogenesis; GO:0045930 negative regulation of mitotic cell cycle; GO:0007165 signal transduction; GO:0019933 cAMP-mediated signaling; GO:0032413 negative regulation of ion transmembrane transporter activity; GO:0033036 macromolecule localization; GO:0051726 regulation of cell cycle; GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway; GO:0098771 inorganic ion homeostasis; GO:0055081 anion homeostasis; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0010942 positive regulation of cell death; GO:0198738 cell-cell signaling by wnt; GO:1900180 regulation of protein localization to nucleus; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0061339 establishment or maintenance of monopolar cell polarity; GO:0070271 protein complex biogenesis; GO:0043549 regulation of kinase activity; GO:0016043 cellular component organization; GO:0045786 negative regulation of cell cycle; GO:0015721 bile acid and bile salt transport; GO:0060255 regulation of macromolecule metabolic process; GO:0043065 positive regulation of apoptotic process; GO:1904589 regulation of protein import; GO:1904590 negative regulation of protein import; GO:0000904 cell morphogenesis involved in differentiation; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:0008361 regulation of cell size; GO:0043408 regulation of MAPK cascade; GO:0023056 positive regulation of signaling; GO:0030033 microvillus assembly; GO:0032410 negative regulation of transporter activity; GO:2001235 positive regulation of apoptotic signaling pathway; GO:0030010 establishment of cell polarity; GO:0010647 positive regulation of cell communication; GO:0035556 intracellular signal transduction; GO:0051049 regulation of transport; GO:0042490 mechanoreceptor differentiation; GO:0001932 regulation of protein phosphorylation; GO:0044802 single-organism membrane organization; GO:0043933 macromolecular complex subunit organization; GO:0034765 regulation of ion transmembrane transport; GO:0010563 negative regulation of phosphorus metabolic process; GO:0042471 ear morphogenesis; GO:0051248 negative regulation of protein metabolic process; GO:1904950 negative regulation of establishment of protein localization; GO:0060119 inner ear receptor cell development; GO:0042981 regulation of apoptotic process; GO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; GO:0060563 neuroepithelial cell differentiation; GO:0071840 cellular component organization or biogenesis; GO:0001738 morphogenesis of a polarized epithelium; GO:0072337 modified amino acid transport; GO:0065008 regulation of biological quality; GO:0051896 regulation of protein kinase B signaling; GO:0070293 renal absorption; GO:0007166 cell surface receptor signaling pathway; GO:1903533 regulation of protein targeting; GO:0035088 establishment or maintenance of apical/basal cell polarity; GO:0051647 nucleus localization; GO:0032989 cellular component morphogenesis; GO:0090002 establishment of protein localization to plasma membrane; GO:0010766 negative regulation of sodium ion transport; GO:1902306 negative regulation of sodium ion transmembrane transport; GO:0050877 neurological system process; GO:0008285 negative regulation of cell proliferation; GO:0030036 actin cytoskeleton organization; GO:0048562 embryonic organ morphogenesis; GO:0032879 regulation of localization; GO:0032528 microvillus organization; GO:0032387 negative regulation of intracellular transport; GO:0008104 protein localization; GO:0046823 negative regulation of nucleocytoplasmic transport; GO:0044765 single-organism transport; GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity; GO:0046903 secretion; GO:0007399 nervous system development; GO:0051174 regulation of phosphorus metabolic process; GO:0006869 lipid transport; GO:0072657 protein localization to membrane; GO:0043269 regulation of ion transport; GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway; GO:2000649 regulation of sodium ion transmembrane transporter activity; GO:0007009 plasma membrane organization; GO:0007163 establishment or maintenance of cell polarity; GO:2000146 negative regulation of cell motility; GO:0031323 regulation of cellular metabolic process; GO:0046942 carboxylic acid transport; GO:0032501 multicellular organismal process; GO:0006814 sodium ion transport; GO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway; GO:0000902 cell morphogenesis; GO:0034762 regulation of transmembrane transport; GO:0048513 animal organ development; GO:0045198 establishment of epithelial cell apical/basal polarity; GO:0043583 ear development; GO:0060158 phospholipase C-activating dopamine receptor signaling pathway; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0009887 animal organ morphogenesis; GO:2001244 positive regulation of intrinsic apoptotic signaling pathway; GO:0043068 positive regulation of programmed cell death; GO:0050794 regulation of cellular process; GO:0007346 regulation of mitotic cell cycle; GO:0042127 regulation of cell proliferation; GO:0031399 regulation of protein modification process; GO:0030859 polarized epithelial cell differentiation; GO:0043067 regulation of programmed cell death; GO:0048523 negative regulation of cellular process; GO:0051239 regulation of multicellular organismal process; GO:1990778 protein localization to cell periphery; GO:0060341 regulation of cellular localization; GO:0042939 tripeptide transport; GO:0030002 cellular anion homeostasis; GO:0014066 regulation of phosphatidylinositol 3-kinase signaling; GO:0070372 regulation of ERK1 and ERK2 cascade; GO:1902578 single-organism localization; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0051338 regulation of transferase activity; GO:0070373 negative regulation of ERK1 and ERK2 cascade; GO:0042491 auditory receptor cell differentiation; GO:0006857 oligopeptide transport; GO:0001933 negative regulation of protein phosphorylation; GO:0007275 multicellular organism development; GO:0032880 regulation of protein localization; GO:0007010 cytoskeleton organization; GO:0035089 establishment of apical/basal cell polarity; GO:0009966 regulation of signal transduction; GO:0006461 protein complex assembly; GO:1904062 regulation of cation transmembrane transport; GO:1902531 regulation of intracellular signal transduction; GO:0051224 negative regulation of protein transport; GO:0048731 system development; GO:0030334 regulation of cell migration; GO:0071702 organic substance transport; GO:0051656 establishment of organelle localization; GO:0009892 negative regulation of metabolic process; GO:0030031 cell projection assembly; GO:0045184 establishment of protein localization; GO:0030182 neuron differentiation; GO:0032415 regulation of sodium:proton antiporter activity; GO:0046822 regulation of nucleocytoplasmic transport; GO:0006873 cellular ion homeostasis; GO:0006811 ion transport; GO:0061024 membrane organization; GO:0030029 actin filament-based process; GO:0043409 negative regulation of MAPK cascade; GO:0007605 sensory perception of sound; GO:1902305 regulation of sodium ion transmembrane transport; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:0015672 monovalent inorganic cation transport; GO:0050793 regulation of developmental process; GO:1902533 positive regulation of intracellular signal transduction; GO:0022008 neurogenesis; GO:0040023 establishment of nucleus localization; GO:0042308 negative regulation of protein import into nucleus; GO:0051234 establishment of localization; GO:2001233 regulation of apoptotic signaling pathway; GO:0010646 regulation of cell communication; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0007600 sensory perception; GO:1903828 negative regulation of cellular protein localization; GO:0071822 protein complex subunit organization; GO:0009888 tissue development; GO:0050801 ion homeostasis; GO:0090162 establishment of epithelial cell polarity; GO:0048522 positive regulation of cellular process; GO:0019725 cellular homeostasis; GO:0032386 regulation of intracellular transport; GO:0022898 regulation of transmembrane transporter activity; GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway; GO:0010155 regulation of proton transport; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0030030 cell projection organization; GO:0002065 columnar/cuboidal epithelial cell differentiation; GO:0060122 inner ear receptor stereocilium organization; GO:0051645 Golgi localization; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0015833 peptide transport; GO:0048856 anatomical structure development; GO:0050954 sensory perception of mechanical stimulus; GO:0051271 negative regulation of cellular component movement; GO:0045859 regulation of protein kinase activity; GO:0030643 cellular phosphate ion homeostasis; GO:0048568 embryonic organ development; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0070201 regulation of establishment of protein localization; GO:0055082 cellular chemical homeostasis; GO:0032782 bile acid secretion; GO:0006812 cation transport; GO:0042326 negative regulation of phosphorylation; GO:0033157 regulation of intracellular protein transport; GO:0009987 cellular process; GO:0019935 cyclic-nucleotide-mediated signaling; GO:0003008 system process; GO:0043271 negative regulation of ion transport; GO:0002066 columnar/cuboidal epithelial cell development; GO:0048585 negative regulation of response to stimulus; GO:0002093 auditory receptor cell morphogenesis; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0006820 anion transport; GO:1904063 negative regulation of cation transmembrane transport; GO:0070727 cellular macromolecule localization; GO:0015711 organic anion transport; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:2001242 regulation of intrinsic apoptotic signaling pathway; GO:0090066 regulation of anatomical structure size; GO:0051128 regulation of cellular component organization; GO:0009967 positive regulation of signal transduction; GO:0040012 regulation of locomotion; GO:0022604 regulation of cell morphogenesis; GO:0071705 nitrogen compound transport; GO:0022612 gland morphogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0098862 cluster of actin-based cell projections; GO:0044421 extracellular region part; GO:0016324 apical plasma membrane; GO:0005903 brush border; GO:0098857 membrane microdomain; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0036126 sperm flagellum; GO:0097729 9+2 motile cilium; GO:0044424 intracellular part; GO:0098858 actin-based cell projection; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0098590 plasma membrane region; GO:0044441 ciliary part; GO:0044425 membrane part; GO:0032426 stereocilium tip; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0098589 membrane region; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0030175 filopodium; GO:0045121 membrane raft; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0031528 microvillus membrane; GO:0045177 apical part of cell; GO:0005929 cilium; GO:0031252 cell leading edge; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0031526 brush border membrane; GO:0012505 endomembrane system; GO:0032421 stereocilium bundle; GO:0031514 motile cilium; GO:0044463 cell projection part; GO:0015629 actin cytoskeleton; GO:0005576 extracellular region; GO:0032420 stereocilium; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0005902 microvillus; GO:0001726 ruffle; GO:0031253 cell projection membrane; GO:0097223 sperm part; GO:0097225 sperm midpiece; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0043621 protein self-association; GO:0005102 receptor binding; GO:0044877 macromolecular complex binding; GO:0070851 growth factor receptor binding; GO:0005515 protein binding; GO:0031698 beta-2 adrenergic receptor binding; GO:0098772 molecular function regulator; GO:0030165 PDZ domain binding; GO:0050780 dopamine receptor binding; GO:0032947 protein complex scaffold; GO:0016247 channel regulator activity; GO:0005488 binding; GO:0031690 adrenergic receptor binding; GO:0001664 G-protein coupled receptor binding; GO:0019904 protein domain specific binding; GO:0019902 phosphatase binding; GO:0005198 structural molecule activity; GO:0019899 enzyme binding; GO:0032403 protein complex binding; GO:0017081 chloride channel regulator activity; GO:0008013 beta-catenin binding; ","K13365","SLC9A3R1; Na(+)/H(+) exchange regulatory cofactor NHE-RF1","hsa04530 Tight junction - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa04928 Parathyroid hormone synthesis, secretion and action - Homo sapiens (human); ","IPR015098; IPR001478; ","\"EBP50, C-terminal; PDZ domain; \"\r"]
["O14773","Tripeptidyl-peptidase 1 OS=Homo sapiens OX=9606 GN=TPP1","TPP1",61.247,35.153,12.4,6,10,6,0.913,0.954,1.039,1.065,1.047,1.065,1.093,0.142,"extracellular\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0006518 peptide metabolic process; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0050877 neurological system process; GO:0048871 multicellular organismal homeostasis; GO:0030968 endoplasmic reticulum unfolded protein response; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0035966 response to topologically incorrect protein; GO:0007154 cell communication; GO:0043171 peptide catabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0007033 vacuole organization; GO:0070887 cellular response to chemical stimulus; GO:0006629 lipid metabolic process; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0060429 epithelium development; GO:0051716 cellular response to stimulus; GO:0009888 tissue development; GO:0044763 single-organism cellular process; GO:0043603 cellular amide metabolic process; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0007040 lysosome organization; GO:1901575 organic substance catabolic process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0044710 single-organism metabolic process; GO:0030163 protein catabolic process; GO:0007417 central nervous system development; GO:0001894 tissue homeostasis; GO:0048856 anatomical structure development; GO:0030855 epithelial cell differentiation; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0033554 cellular response to stress; GO:0016043 cellular component organization; GO:0035967 cellular response to topologically incorrect protein; GO:0034976 response to endoplasmic reticulum stress; GO:0071310 cellular response to organic substance; GO:0036498 IRE1-mediated unfolded protein response; GO:0050896 response to stimulus; GO:0060249 anatomical structure homeostasis; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:0044248 cellular catabolic process; GO:0006508 proteolysis; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0050885 neuromuscular process controlling balance; GO:0009987 cellular process; GO:0048771 tissue remodeling; GO:0006986 response to unfolded protein; GO:0003008 system process; GO:0006950 response to stress; GO:0034620 cellular response to unfolded protein; GO:0048731 system development; GO:0006807 nitrogen compound metabolic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0045453 bone resorption; GO:1901565 organonitrogen compound catabolic process; GO:0044767 single-organism developmental process; GO:0006996 organelle organization; GO:0009057 macromolecule catabolic process; GO:0080171 lytic vacuole organization; GO:0050905 neuromuscular process; GO:0046849 bone remodeling; GO:0009056 catabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; GO:1901564 organonitrogen compound metabolic process; ","GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0042470 melanosome; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0043202 lysosomal lumen; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0048770 pigment granule; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0044437 vacuolar part; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0005773 vacuole; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0000323 lytic vacuole; ","GO:0008238 exopeptidase activity; GO:0008233 peptidase activity; GO:0043167 ion binding; GO:0008236 serine-type peptidase activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0033218 amide binding; GO:0004175 endopeptidase activity; GO:0004252 serine-type endopeptidase activity; GO:0003824 catalytic activity; GO:0017171 serine hydrolase activity; GO:0042277 peptide binding; GO:0008240 tripeptidyl-peptidase activity; GO:0005488 binding; GO:0046872 metal ion binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0043169 cation binding; ","K01279","TPP1; tripeptidyl-peptidase I [EC:3.4.14.9]","hsa04142 Lysosome - Homo sapiens (human); ","IPR009020; IPR030400; IPR000209; IPR015366; ","\"Proteinase propeptide inhibitor; Sedolisin domain; Peptidase S8/S53 domain; Peptidase S53, activation domain; \"\r"]
["O14776","Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1","TCERG1",123.9,31.828,10.4,9,9,9,0.977,0.925,0.976,1.036,1.013,1.042,1.074,0.0232,"nucleus\r","GO:0097659 nucleic acid-templated transcription; GO:0009058 biosynthetic process; GO:0051253 negative regulation of RNA metabolic process; GO:0044237 cellular metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0043170 macromolecule metabolic process; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0000122 negative regulation of transcription from RNA polymerase II promoter; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:1902679 negative regulation of RNA biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0071704 organic substance metabolic process; GO:0045892 negative regulation of transcription, DNA-templated; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0009892 negative regulation of metabolic process; GO:0044249 cellular biosynthetic process; GO:0009890 negative regulation of biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0006366 transcription from RNA polymerase II promoter; GO:0010467 gene expression; GO:0031327 negative regulation of cellular biosynthetic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0003723 RNA binding; GO:0003714 transcription corepressor activity; GO:0001103 RNA polymerase II repressing transcription factor binding; GO:0005515 protein binding; GO:0003712 transcription cofactor activity; GO:0070064 proline-rich region binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0001104 RNA polymerase II transcription cofactor activity; GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding; GO:0070491 repressing transcription factor binding; GO:0005488 binding; GO:0001085 RNA polymerase II transcription factor binding; GO:0003676 nucleic acid binding; GO:0001106 RNA polymerase II transcription corepressor activity; GO:0000989 transcription factor activity, transcription factor binding; GO:0003713 transcription coactivator activity; GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding; GO:0000988 transcription factor activity, protein binding; GO:0008134 transcription factor binding; ","K12824","TCERG1; transcription elongation regulator 1","hsa03040 Spliceosome - Homo sapiens (human); ","IPR002713; IPR001202; ","FF domain; WW domain; \r"]
["O14786","Neuropilin-1 OS=Homo sapiens OX=9606 GN=NRP1","NRP1",103.13,45.395,9.2,8,8,8,1.057,1.146,1.07,0.893,0.932,0.951,0.848,0.00626,"endoplasmic reticulum\r",{"$cut":{"chars":20004,"head":"GO:0044700 single organism signaling; GO:0060839 endothelial cell fate commitment; GO:0010941 regulation of cell death; GO:0090130 tissue migration; GO:0048008 platelet-derived growth factor receptor signaling pathway; GO:0048732 gland development; GO:0035282 segmentation; GO:0043523 regulation of neuron apoptotic process; GO:0010594 regulation of endothelial cell migration; GO:0048754 branching morphogenesis of an epithelial tube; GO:0045927 positive regulation of growth; GO:0001558 regulation of cell growth; GO:0001525 angiogenesis; GO:0044093 positive regulation of molecular function; GO:1905040 otic placode development; GO:0032535 regulation of cellular component size; GO:0009790 embryo development; GO:0051099 positive regulation of binding; GO:0001569 branching involved in blood vessel morphogenesis; GO:0060445 branching involved in salivary gland morphogenesis; GO:0042325 regulation of phosphorylation; GO:0048485 sympathetic nervous system development; GO:0051716 cellular response to stimulus; GO:0035767 endothelial cell chemotaxis; GO:0080090 regulation of primary metabolic process; GO:0030307 positive regulation of cell growth; GO:0048699 generation of neurons; GO:0035239 tube morphogenesis; GO:0001763 morphogenesis of a branching structure; GO:0044763 single-organism cellular process; GO:0048870 cell motility; GO:0006935 chemotaxis; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0060976 coronary vasculature development; GO:0006810 transport; GO:0060384 innervation; GO:0007267 cell-cell signaling; GO:0048583 regulation of response to stimulus; GO:0045665 negative regulation of neuron differentiation; GO:0021675 nerve development; GO:0048844 artery morphogenesis; GO:0048010 vascular endothelial growth factor receptor signaling pathway; GO:0010721 negative regulation of cell development; GO:0060548 negative regulation of cell death; GO:0097101 blood vessel endothelial cell fate specification; GO:0010975 regulation of neuron projection development; GO:0061552 ganglion morphogenesis; GO:0030855 epithelial cell differentiation; GO:0072359 circulatory system development; GO:0090259 regulation of retinal ganglion cell axon guidance; GO:0002009 morphogenesis of an epithelium; GO:0044707 single-multicellular organism process; GO:0021979 hypothalamus cell differentiation; GO:0021785 branchiomotor neuron axon guidance; GO:0060847 endothelial cell fate specification; GO:0060978 angiogenesis involved in coronary vascular morphogenesis; GO:0007389 pattern specification process; GO:1990138 neuron projection extension; GO:0048519 negative regulation of biological process; GO:0021953 central nervous system neuron differentiation; GO:0038084 vascular endothelial growth factor signaling pathway; GO:0036010 protein localization to endosome; GO:0009653 anatomical structure morphogenesis; GO:0001654 eye development; GO:0021879 forebrain neuron differentiation; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0043524 negative regulation of neuron apoptotic process; GO:0050772 positive regulation of axonogenesis; GO:2000145 regulation of cell motility; GO:0021604 cranial nerve structural organization; GO:0031345 negative regulation of cell projection organization; GO:0021602 cranial nerve morphogenesis; GO:0001936 regulation of endothelial cell proliferation; GO:0034613 cellular protein localization; GO:0048646 anatomical structure formation involved in morphogenesis; GO:1901215 negative regulation of neuron death; GO:0061438 renal system vasculature morphogenesis; GO:0001822 kidney development; GO:0010771 negative regulation of cell morphogenesis involved in differentiation; GO:0060562 epithelial tube morphogenesis; GO:0097491 sympathetic neuron projection guidance; GO:0006950 response to stress; GO:0051270 regulation of cellular component movement; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0010977 negative regulation of neuron projection development; GO:0032101 regulation of response to external stimulus; GO"}},"GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0043025 neuronal cell body; GO:0031224 intrinsic component of membrane; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0030426 growth cone; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0005925 focal adhesion; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:0043005 neuron projection; GO:0005768 endosome; GO:0030055 cell-substrate junction; GO:0005883 neurofilament; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0005924 cell-substrate adherens junction; GO:0002116 semaphorin receptor complex; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0099513 polymeric cytoskeletal fiber; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0043235 receptor complex; GO:0012505 endomembrane system; GO:0097443 sorting endosome; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0030427 site of polarized growth; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0099081 supramolecular polymer; GO:0005886 plasma membrane; GO:0030424 axon; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0045111 intermediate filament cytoskeleton; GO:0005882 intermediate filament; GO:0009986 cell surface; GO:0044297 cell body; GO:0044444 cytoplasmic part; ","GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0019838 growth factor binding; GO:0015026 coreceptor activity; GO:0017154 semaphorin receptor activity; GO:0004713 protein tyrosine kinase activity; GO:0005515 protein binding; GO:0004672 protein kinase activity; GO:0004888 transmembrane signaling receptor activity; GO:0008201 heparin binding; GO:0004871 signal transducer activity; GO:0004714 transmembrane receptor protein tyrosine kinase activity; GO:0016301 kinase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0005539 glycosaminoglycan binding; GO:0016740 transferase activity; GO:0038023 signaling receptor activity; GO:0038085 vascular endothelial growth factor binding; GO:0043167 ion binding; GO:1901681 sulfur compound binding; GO:0019955 cytokine binding; GO:0019199 transmembrane receptor protein kinase activity; GO:0060089 molecular transducer activity; GO:0097367 carbohydrate derivative binding; GO:0004872 receptor activity; GO:0005021 vascular endothelial growth factor-activated receptor activity; GO:0046872 metal ion binding; GO:0099600 transmembrane receptor activity; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K06724","NRP1; neuropilin 1","hsa05166 HTLV-I infection - Homo sapiens (human); hsa04360 Axon guidance - Homo sapiens (human); ","IPR000421; IPR000859; IPR000998; IPR013320; IPR022579; IPR008979; ","\"Coagulation factor 5/8 C-terminal domain; CUB domain; MAM domain; Concanavalin A-like lectin/glucanase domain; Neuropilin, C-terminal; Galactose-binding domain-like; \"\r"]
["O14787","Transportin-2 OS=Homo sapiens OX=9606 GN=TNPO2","TNPO2",101.39,29.355,12.4,9,11,6,1.22,1.057,0.965,0.911,0.894,0.974,0.857,0.109,"cytoplasm\r","GO:0046907 intracellular transport; GO:0006607 NLS-bearing protein import into nucleus; GO:0072594 establishment of protein localization to organelle; GO:0000060 protein import into nucleus, translocation; GO:0017038 protein import; GO:1902593 single-organism nuclear import; GO:0044699 single-organism process; GO:0071702 organic substance transport; GO:0051169 nuclear transport; GO:0006610 ribosomal protein import into nucleus; GO:0015031 protein transport; GO:1902582 single-organism intracellular transport; GO:0051641 cellular localization; GO:0051234 establishment of localization; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:0006605 protein targeting; GO:0070727 cellular macromolecule localization; GO:0051649 establishment of localization in cell; GO:1902578 single-organism localization; GO:0051170 nuclear import; GO:0006886 intracellular protein transport; GO:0044744 protein targeting to nucleus; GO:0006913 nucleocytoplasmic transport; GO:1902580 single-organism cellular localization; GO:0033365 protein localization to organelle; GO:0034613 cellular protein localization; GO:0006606 protein import into nucleus; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0051179 localization; GO:0034504 protein localization to nucleus; GO:0044765 single-organism transport; ","GO:0016020 membrane; GO:0043229 intracellular organelle; GO:0031090 organelle membrane; GO:0005635 nuclear envelope; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031965 nuclear membrane; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0031975 envelope; GO:0034399 nuclear periphery; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0031267 small GTPase binding; GO:0005048 signal sequence binding; GO:0008565 protein transporter activity; GO:0017016 Ras GTPase binding; GO:0042277 peptide binding; GO:0005488 binding; GO:0008139 nuclear localization sequence binding; GO:0022892 substrate-specific transporter activity; GO:0008536 Ran GTPase binding; GO:0005515 protein binding; GO:0033218 amide binding; GO:0051020 GTPase binding; GO:0019899 enzyme binding; GO:0005215 transporter activity; ","K18727",null,null,"IPR001494; IPR011989; IPR016024; ","\"Importin-beta, N-terminal domain; Armadillo-like helical; Armadillo-type fold; \"\r"]
["O14791","Apolipoprotein L1 OS=Homo sapiens OX=9606 GN=APOL1","APOL1",43.974,10.936,13.6,6,12,6,0.987,0.962,0.939,1.06,1.028,1.042,1.084,0.00886,"endoplasmic reticulum\r","GO:0098661 inorganic anion transmembrane transport; GO:0065008 regulation of biological quality; GO:0019835 cytolysis; GO:0034220 ion transmembrane transport; GO:1901615 organic hydroxy compound metabolic process; GO:1902652 secondary alcohol metabolic process; GO:0006066 alcohol metabolic process; GO:0044699 single-organism process; GO:0006821 chloride transport; GO:0035821 modification of morphology or physiology of other organism; GO:0050896 response to stimulus; GO:0016125 sterol metabolic process; GO:0098656 anion transmembrane transport; GO:0042157 lipoprotein metabolic process; GO:0045087 innate immune response; GO:1902476 chloride transmembrane transport; GO:0051234 establishment of localization; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:1902578 single-organism localization; GO:0031640 killing of cells of other organism; GO:0006898 receptor-mediated endocytosis; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0033036 macromolecule localization; GO:0001906 cell killing; GO:0009987 cellular process; GO:0044765 single-organism transport; GO:0006629 lipid metabolic process; GO:0008203 cholesterol metabolic process; GO:0006869 lipid transport; GO:0006950 response to stress; GO:0098660 inorganic ion transmembrane transport; GO:0016192 vesicle-mediated transport; GO:0044281 small molecule metabolic process; GO:0008202 steroid metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0010876 lipid localization; GO:0071702 organic substance transport; GO:0002376 immune system process; GO:0006897 endocytosis; GO:0044238 primary metabolic process; GO:0051704 multi-organism process; GO:0006820 anion transport; GO:0006810 transport; GO:0055085 transmembrane transport; GO:0006811 ion transport; GO:0044710 single-organism metabolic process; GO:0044364 disruption of cells of other organism; GO:0006952 defense response; GO:0051179 localization; GO:0006955 immune response; GO:0015698 inorganic anion transport; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0072562 blood microparticle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0032994 protein-lipid complex; GO:0044425 membrane part; GO:1990777 lipoprotein particle; GO:0034358 plasma lipoprotein particle; GO:0034385 triglyceride-rich plasma lipoprotein particle; GO:0031224 intrinsic component of membrane; GO:0032991 macromolecular complex; GO:0034364 high-density lipoprotein particle; GO:0034361 very-low-density lipoprotein particle; GO:0005576 extracellular region; ","GO:0015075 ion transmembrane transporter activity; GO:0022803 passive transmembrane transporter activity; GO:0005253 anion channel activity; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0005254 chloride channel activity; GO:0015267 channel activity; GO:0015103 inorganic anion transmembrane transporter activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0015108 chloride transmembrane transporter activity; GO:0022838 substrate-specific channel activity; GO:0005488 binding; GO:0008289 lipid binding; GO:0005216 ion channel activity; GO:0008509 anion transmembrane transporter activity; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; ","K14480","APOL; apolipoprotein L","hsa05143 African trypanosomiasis - Homo sapiens (human); "]
["O14807","Ras-related protein M-Ras OS=Homo sapiens OX=9606 GN=MRAS","MRAS",23.846,2.4492,7.2,2,2,2,1.151,1.062,1.419,0.938,0.814,0.649,0.661,0.0387,"cyto_nucl\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0030036 actin cytoskeleton organization; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0061061 muscle structure development; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0035556 intracellular signal transduction; GO:0048731 system development; GO:0044763 single-organism cellular process; GO:0007264 small GTPase mediated signal transduction; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:1902589 single-organism organelle organization; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0007517 muscle organ development; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0030029 actin filament-based process; GO:0048856 anatomical structure development; GO:0007265 Ras protein signal transduction; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0005622 intracellular; GO:0044464 cell part; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; GO:0005886 plasma membrane; ","GO:1901265 nucleoside phosphate binding; GO:0030742 GTP-dependent protein binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0003924 GTPase activity; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019001 guanyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0036094 small molecule binding; ","K07831","MRAS; Ras-related protein M-Ras","hsa04072 Phospholipase D signaling pathway - Homo sapiens (human); hsa04015 Rap1 signaling pathway - Homo sapiens (human); hsa04218 Cellular senescence - Homo sapiens (human); hsa04625 C-type lectin receptor signaling pathway - Homo sapiens (human); hsa04371 Apelin signaling pathway - Homo sapiens (human); hsa04137 Mitophagy - animal - Homo sapiens (human); hsa04014 Ras signaling pathway - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa04010 MAPK signaling pathway - Homo sapiens (human); hsa05166 HTLV-I infection - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa04140 Autophagy - animal - Homo sapiens (human); ","IPR005225; IPR027417; ","Small GTP-binding protein domain; P-loop containing nucleoside triphosphate hydrolase; \r"]
["O14818","Proteasome subunit alpha type-7 OS=Homo sapiens OX=9606 GN=PSMA7","PSMA7",27.887,66.727,41.1,10,21,10,0.974,0.975,0.936,1.007,1.078,1.05,1.087,0.0258,"cytoplasm\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0002220 innate immune response activating cell surface receptor signaling pathway; GO:0007166 cell surface receptor signaling pathway; GO:0010608 posttranscriptional regulation of gene expression; GO:0051443 positive regulation of ubiquitin-protein transferase activity; GO:0031347 regulation of defense response; GO:0071345 cellular response to cytokine stimulus; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:1903364 positive regulation of cellular protein catabolic process; GO:0008152 metabolic process; GO:0044093 positive regulation of molecular function; GO:0090263 positive regulation of canonical Wnt signaling pathway; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0051347 positive regulation of transferase activity; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0016055 Wnt signaling pathway; GO:0044419 interspecies interaction between organisms; GO:1903362 regulation of cellular protein catabolic process; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0006521 regulation of cellular amino acid metabolic process; GO:0002758 innate immune response-activating signal transduction; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0010972 negative regulation of G2/M transition of mitotic cell cycle; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0060828 regulation of canonical Wnt signaling pathway; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0033209 tumor necrosis factor-mediated signaling pathway; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0000165 MAPK cascade; GO:1903506 regulation of nucleic acid-templated transcription; GO:2000058 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0019884 antigen processing and presentation of exogenous antigen; GO:1901575 organic substance catabolic process; GO:0010948 negative regulation of cell cycle process; GO:0007267 cell-cell signaling; GO:0002223 stimulatory C-type lectin receptor signaling pathway; GO:0032269 negative regulation of cellular protein metabolic process; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0030163 protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0060071 Wnt signaling pathway, planar cell polarity pathway; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:0002682 regulation of immune system process; GO:0006464 cellular protein modification process; GO:0031145 anaphase-promoting complex-dependent catabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016310 phosphorylation; GO:0033554 cellular response to stress; GO:0007346 regulation of mitotic cell cycle; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0051239 regulation of multicellular organismal process; GO:0043487 regulation of RNA stability; GO:0000209 protein polyubiquitination; GO:0031349 positive regulation of defense response; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0009889 regulation of biosynthetic process; GO:1901987 regulation of cell cycle phase transition; GO:0009896 positive regulation of catabolic process; GO:0043620 regulation of DNA-templated transcription in response to stress; GO:0070482 response to oxygen levels; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0044248 cellular catabolic process; GO:0010389 regulation of G2/M transition of mitotic cell cycle; GO:0042176 regulation of protein catabolic process; GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; GO:0038093 Fc receptor signaling pathway; GO:0050778 positive regulation of immune response; GO:0009966 regulation of signal transduction; GO:0023014 signal transduction by protein phosphorylation; GO:0071456 cellular response to hypoxia; GO:0038061 NIK/NF-kappaB signaling; GO:0002253 activation of immune response; GO:0006950 response to stress; GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; GO:0016567 protein ubiquitination; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress; GO:1904666 regulation of ubiquitin protein ligase activity; GO:1903321 negative regulation of protein modification by small protein conjugation or removal; GO:0055085 transmembrane transport; GO:0051247 positive regulation of protein metabolic process; GO:0051438 regulation of ubiquitin-protein transferase activity; GO:0031398 positive regulation of protein ubiquitination; GO:0032446 protein modification by small protein conjugation; GO:0006793 phosphorus metabolic process; GO:0030111 regulation of Wnt signaling pathway; GO:0031325 positive regulation of cellular metabolic process; GO:0030177 positive regulation of Wnt signaling pathway; GO:1904668 positive regulation of ubiquitin protein ligase activity; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0036293 response to decreased oxygen levels; GO:0051179 localization; GO:0043412 macromolecule modification; GO:0048584 positive regulation of response to stimulus; GO:0050793 regulation of developmental process; GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process; GO:0051444 negative regulation of ubiquitin-protein transferase activity; GO:0070646 protein modification by small protein removal; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0031331 positive regulation of cellular catabolic process; GO:0090090 negative regulation of canonical Wnt signaling pathway; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0031400 negative regulation of protein modification process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0035567 non-canonical Wnt signaling pathway; GO:0031396 regulation of protein ubiquitination; GO:1905330 regulation of morphogenesis of an epithelium; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0045930 negative regulation of mitotic cell cycle; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0045088 regulation of innate immune response; GO:1901991 negative regulation of mitotic cell cycle phase transition; GO:0009893 positive regulation of metabolic process; GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0034612 response to tumor necrosis factor; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0051726 regulation of cell cycle; GO:0070887 cellular response to chemical stimulus; GO:0050851 antigen receptor-mediated signaling pathway; GO:0010468 regulation of gene expression; GO:0030178 negative regulation of Wnt signaling pathway; GO:0034097 response to cytokine; GO:0031326 regulation of cellular biosynthetic process; GO:0048002 antigen processing and presentation of peptide antigen; GO:0048522 positive regulation of cellular process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0051348 negative regulation of transferase activity; GO:0070647 protein modification by small protein conjugation or removal; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0198738 cell-cell signaling by wnt; GO:0010565 regulation of cellular ketone metabolic process; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0036211 protein modification process; GO:2000026 regulation of multicellular organismal development; GO:0090175 regulation of establishment of planar polarity; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0045786 negative regulation of cell cycle; GO:1904667 negative regulation of ubiquitin protein ligase activity; GO:0002218 activation of innate immune response; GO:0044257 cellular protein catabolic process; GO:0071356 cellular response to tumor necrosis factor; GO:1901988 negative regulation of cell cycle phase transition; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0016579 protein deubiquitination; GO:0050896 response to stimulus; GO:0010498 proteasomal protein catabolic process; GO:0071704 organic substance metabolic process; GO:1903322 positive regulation of protein modification by small protein conjugation or removal; GO:0045862 positive regulation of proteolysis; GO:2000027 regulation of organ morphogenesis; GO:0006468 protein phosphorylation; GO:0023056 positive regulation of signaling; GO:0016032 viral process; GO:0001666 response to hypoxia; GO:0002757 immune response-activating signal transduction; GO:0006508 proteolysis; GO:0010647 positive regulation of cell communication; GO:0071453 cellular response to oxygen levels; GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:0019221 cytokine-mediated signaling pathway; GO:0009987 cellular process; GO:0033238 regulation of cellular amine metabolic process; GO:0031397 negative regulation of protein ubiquitination; GO:0043632 modification-dependent macromolecule catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0045089 positive regulation of innate immune response; GO:0006355 regulation of transcription, DNA-templated; GO:0035556 intracellular signal transduction; GO:0019941 modification-dependent protein catabolic process; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition; GO:0031401 positive regulation of protein modification process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia; GO:1902749 regulation of cell cycle G2/M phase transition; GO:0043488 regulation of mRNA stability; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0019882 antigen processing and presentation; GO:0050852 T cell receptor signaling pathway; GO:0051246 regulation of protein metabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0002684 positive regulation of immune system process; GO:0009057 macromolecule catabolic process; GO:0038095 Fc-epsilon receptor signaling pathway; GO:0051248 negative regulation of protein metabolic process; GO:0022402 cell cycle process; GO:0045732 positive regulation of protein catabolic process; GO:0009967 positive regulation of signal transduction; GO:1902750 negative regulation of cell cycle G2/M phase transition; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0036294 cellular response to decreased oxygen levels; GO:0065007 biological regulation; ","GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:1905369 endopeptidase complex; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:1905368 peptidase complex; GO:0043227 membrane-bounded organelle; GO:0044456 synapse part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0019773 proteasome core complex, alpha-subunit complex; GO:0000502 proteasome complex; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0045202 synapse; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0098794 postsynapse; GO:0005839 proteasome core complex; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0004175 endopeptidase activity; GO:0004298 threonine-type endopeptidase activity; GO:0008233 peptidase activity; GO:0042802 identical protein binding; GO:0070003 threonine-type peptidase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0016787 hydrolase activity; GO:0005515 protein binding; ","K02731","PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]","hsa03050 Proteasome - Homo sapiens (human); ","IPR029055; IPR000426; ","\"Nucleophile aminohydrolases, N-terminal; Proteasome alpha-subunit, N-terminal domain; \"\r"]
["O14828","Secretory carrier-associated membrane protein 3 OS=Homo sapiens OX=9606 GN=SCAMP3","SCAMP3",38.287,8.9931,4.6,1,2,1,1,1.054,1.047,0.837,1.081,0.988,0.937,0.412,"plasma membrane\r","GO:0001101 response to acid chemical; GO:0016192 vesicle-mediated transport; GO:1901700 response to oxygen-containing compound; GO:0048193 Golgi vesicle transport; GO:0071702 organic substance transport; GO:0010033 response to organic substance; GO:0050896 response to stimulus; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006810 transport; GO:0045184 establishment of protein localization; GO:0033993 response to lipid; GO:0042221 response to chemical; GO:0032526 response to retinoic acid; GO:0008104 protein localization; GO:0051179 localization; GO:0006892 post-Golgi vesicle-mediated transport; GO:0033036 macromolecule localization; ","GO:0016020 membrane; GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0098588 bounding membrane of organelle; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0000139 Golgi membrane; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0005794 Golgi apparatus; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0031625 ubiquitin protein ligase binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0005488 binding; GO:0019899 enzyme binding; ","K19995"]
["O14841","5-oxoprolinase OS=Homo sapiens OX=9606 GN=OPLAH","OPLAH",137.46,24.806,6.4,7,8,7,0.962,0.97,1.048,1.021,0.979,1.013,1.011,0.72,"cytoplasm\r","GO:0006790 sulfur compound metabolic process; GO:0006518 peptide metabolic process; GO:0043043 peptide biosynthetic process; GO:0042398 cellular modified amino acid biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0009058 biosynthetic process; GO:0043603 cellular amide metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:1901576 organic substance biosynthetic process; GO:0044237 cellular metabolic process; GO:0044249 cellular biosynthetic process; GO:0044272 sulfur compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006575 cellular modified amino acid metabolic process; GO:0006749 glutathione metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043604 amide biosynthetic process; GO:0009987 cellular process; GO:0019184 nonribosomal peptide biosynthetic process; GO:0006750 glutathione biosynthetic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0017168 5-oxoprolinase (ATP-hydrolyzing) activity; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides; GO:0016787 hydrolase activity; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K01469","OPLAH; 5-oxoprolinase (ATP-hydrolysing) [EC:3.5.2.9]","hsa00480 Glutathione metabolism - Homo sapiens (human); ","IPR008040; ","\"Hydantoinaseoxoprolinase, N-terminal; \"\r"]
["O14880","Microsomal glutathione S-transferase 3 OS=Homo sapiens OX=9606 GN=MGST3","MGST3",16.516,4.7099,19.7,2,4,2,1.113,1.088,1.062,0.95,0.939,0.915,0.859,0.00098,"extracellular\r","GO:0071466 cellular response to xenobiotic stimulus; GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0050896 response to stimulus; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:0044272 sulfur compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0007165 signal transduction; GO:1901685 glutathione derivative metabolic process; GO:0008152 metabolic process; GO:1990748 cellular detoxification; GO:0006805 xenobiotic metabolic process; GO:0009410 response to xenobiotic stimulus; GO:0007154 cell communication; GO:0009719 response to endogenous stimulus; GO:0098869 cellular oxidant detoxification; GO:0009987 cellular process; GO:0070887 cellular response to chemical stimulus; GO:0006629 lipid metabolic process; GO:0006790 sulfur compound metabolic process; GO:0051716 cellular response to stimulus; GO:0044711 single-organism biosynthetic process; GO:0009636 response to toxic substance; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0023052 signaling; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:1901687 glutathione derivative biosynthetic process; GO:0010243 response to organonitrogen compound; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0044710 single-organism metabolic process; GO:1901698 response to nitrogen compound; GO:0098754 detoxification; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043229 intracellular organelle; GO:0005635 nuclear envelope; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0012505 endomembrane system; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044432 endoplasmic reticulum part; GO:0031975 envelope; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0004364 glutathione transferase activity; GO:0004602 glutathione peroxidase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016209 antioxidant activity; GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups; GO:0005515 protein binding; GO:0004601 peroxidase activity; GO:0016740 transferase activity; GO:0016684 oxidoreductase activity, acting on peroxide as acceptor; GO:0016491 oxidoreductase activity; ","K00799","GST; glutathione S-transferase [EC:2.5.1.18]","hsa01524 Platinum drug resistance - Homo sapiens (human); hsa00480 Glutathione metabolism - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa05204 Chemical carcinogenesis - Homo sapiens (human); hsa00980 Metabolism of xenobiotics by cytochrome P450 - Homo sapiens (human); hsa05225 Hepatocellular carcinoma - Homo sapiens (human); hsa00983 Drug metabolism - other enzymes - Homo sapiens (human); hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human); hsa00982 Drug metabolism - cytochrome P450 - Homo sapiens (human); hsa05215 Prostate cancer - Homo sapiens (human); ","IPR023352; ","Membrane associated eicosanoid/glutathione metabolism-like domain; \r"]
["O14896","Interferon regulatory factor 6 OS=Homo sapiens OX=9606 GN=IRF6","IRF6",53.129,9.0971,14.3,5,6,5,0.977,1.063,0.927,1.036,0.96,1.048,1.026,0.614,"mitochondria\r","GO:0044700 single organism signaling; GO:0043616 keratinocyte proliferation; GO:0048732 gland development; GO:0007166 cell surface receptor signaling pathway; GO:0097659 nucleic acid-templated transcription; GO:0048869 cellular developmental process; GO:0071346 cellular response to interferon-gamma; GO:0009891 positive regulation of biosynthetic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0071345 cellular response to cytokine stimulus; GO:0008285 negative regulation of cell proliferation; GO:0060333 interferon-gamma-mediated signaling pathway; GO:0061180 mammary gland epithelium development; GO:2001141 regulation of RNA biosynthetic process; GO:0009913 epidermal cell differentiation; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0008544 epidermis development; GO:0060644 mammary gland epithelial cell differentiation; GO:0043170 macromolecule metabolic process; GO:0051726 regulation of cell cycle; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0060429 epithelium development; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0043588 skin development; GO:0030216 keratinocyte differentiation; GO:0009888 tissue development; GO:0031326 regulation of cellular biosynthetic process; GO:0034097 response to cytokine; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0034340 response to type I interferon; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0016070 RNA metabolic process; GO:0050673 epithelial cell proliferation; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006952 defense response; GO:0048856 anatomical structure development; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0030855 epithelial cell differentiation; GO:0050794 regulation of cellular process; GO:0060337 type I interferon signaling pathway; GO:0044707 single-multicellular organism process; GO:0045786 negative regulation of cell cycle; GO:0006725 cellular aromatic compound metabolic process; GO:0042127 regulation of cell proliferation; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0045087 innate immune response; GO:0030879 mammary gland development; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0071357 cellular response to type I interferon; GO:0007275 multicellular organism development; GO:0009059 macromolecule biosynthetic process; GO:0019221 cytokine-mediated signaling pathway; GO:0009987 cellular process; GO:0051254 positive regulation of RNA metabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0006950 response to stress; GO:0007050 cell cycle arrest; GO:0048731 system development; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0008283 cell proliferation; GO:0002376 immune system process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0034341 response to interferon-gamma; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0044767 single-organism developmental process; GO:0031325 positive regulation of cellular metabolic process; GO:0010467 gene expression; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0022402 cell cycle process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0006955 immune response; GO:0007049 cell cycle; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0000975 regulatory region DNA binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003677 DNA binding; GO:0001067 regulatory region nucleic acid binding; GO:0005488 binding; GO:0001071 nucleic acid binding transcription factor activity; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0003700 transcription factor activity, sequence-specific DNA binding; ","K10154",null,null,"IPR017855; IPR011991; IPR001346; IPR008984; IPR019471; ","SMAD domain-like; Winged helix-turn-helix DNA-binding domain; Interferon regulatory factor DNA-binding domain; SMAD/FHA domain; Interferon regulatory factor-3; \r"]
["O14907","Tax1-binding protein 3 OS=Homo sapiens OX=9606 GN=TAX1BP3","TAX1BP3",13.735,12.893,25.8,3,4,3,1.079,0.791,1.047,1.088,0.915,1.084,1.058,0.611,"cytoplasm\r","GO:0044700 single organism signaling; GO:0050794 regulation of cellular process; GO:0042127 regulation of cell proliferation; GO:0009968 negative regulation of signal transduction; GO:0007166 cell surface receptor signaling pathway; GO:0023051 regulation of signaling; GO:2000008 regulation of protein localization to cell surface; GO:0044699 single-organism process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:0060341 regulation of cellular localization; GO:0008285 negative regulation of cell proliferation; GO:0090630 activation of GTPase activity; GO:0007165 signal transduction; GO:0023057 negative regulation of signaling; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0010648 negative regulation of cell communication; GO:0051345 positive regulation of hydrolase activity; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0007266 Rho protein signal transduction; GO:0032880 regulation of protein localization; GO:0016055 Wnt signaling pathway; GO:0009987 cellular process; GO:0009966 regulation of signal transduction; GO:0051716 cellular response to stimulus; GO:1903828 negative regulation of cellular protein localization; GO:0030178 negative regulation of Wnt signaling pathway; GO:0035556 intracellular signal transduction; GO:0043547 positive regulation of GTPase activity; GO:0044763 single-organism cellular process; GO:0007264 small GTPase mediated signal transduction; GO:0048585 negative regulation of response to stimulus; GO:0023052 signaling; GO:0198738 cell-cell signaling by wnt; GO:0043085 positive regulation of catalytic activity; GO:2000009 negative regulation of protein localization to cell surface; GO:0050789 regulation of biological process; GO:0007267 cell-cell signaling; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0051336 regulation of hydrolase activity; GO:0030111 regulation of Wnt signaling pathway; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0065009 regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0007265 Ras protein signal transduction; GO:1903827 regulation of cellular protein localization; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044452 nucleolar part; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0015629 actin cytoskeleton; GO:0001650 fibrillar center; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0008022 protein C-terminus binding; GO:0005515 protein binding; GO:0005488 binding; GO:0008013 beta-catenin binding; ",{"$nulls":3},"IPR001478; ","PDZ domain; \r"]
["O14908","PDZ domain-containing protein GIPC1 OS=Homo sapiens OX=9606 GN=GIPC1","GIPC1",36.049,30.883,16.5,5,5,5,0.835,0.928,0.818,1.045,1.125,1.176,1.296,0.00754,"nucleus\r","GO:0044700 single organism signaling; GO:0046717 acid secretion; GO:0065008 regulation of biological quality; GO:0090130 tissue migration; GO:0051674 localization of cell; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0010564 regulation of cell cycle process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0090100 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0043542 endothelial cell migration; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0098916 anterograde trans-synaptic signaling; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0090068 positive regulation of cell cycle process; GO:0051726 regulation of cell cycle; GO:1903362 regulation of cellular protein catabolic process; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:1903846 positive regulation of cellular response to transforming growth factor beta stimulus; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0090287 regulation of cellular response to growth factor stimulus; GO:0048870 cell motility; GO:0046942 carboxylic acid transport; GO:1903363 negative regulation of cellular protein catabolic process; GO:0031323 regulation of cellular metabolic process; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0051302 regulation of cell division; GO:0007267 cell-cell signaling; GO:0010631 epithelial cell migration; GO:0032940 secretion by cell; GO:0032269 negative regulation of cellular protein metabolic process; GO:0048583 regulation of response to stimulus; GO:0061136 regulation of proteasomal protein catabolic process; GO:0001667 ameboidal-type cell migration; GO:0019222 regulation of metabolic process; GO:0040011 locomotion; GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0014047 glutamate secretion; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0044707 single-multicellular organism process; GO:0016477 cell migration; GO:0042177 negative regulation of protein catabolic process; GO:1903051 negative regulation of proteolysis involved in cellular protein catabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0017015 regulation of transforming growth factor beta receptor signaling pathway; GO:0090132 epithelium migration; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0032465 regulation of cytokinesis; GO:1901799 negative regulation of proteasomal protein catabolic process; GO:0032467 positive regulation of cytokinesis; GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:1902578 single-organism localization; GO:0023056 positive regulation of signaling; GO:0006886 intracellular protein transport; GO:0006865 amino acid transport; GO:0099537 trans-synaptic signaling; GO:0009895 negative regulation of catabolic process; GO:0010647 positive regulation of cell communication; GO:0042176 regulation of protein catabolic process; GO:0034613 cellular protein localization; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:0048167 regulation of synaptic plasticity; GO:0045787 positive regulation of cell cycle; GO:0045861 negative regulation of proteolysis; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0051781 positive regulation of cell division; GO:0050804 modulation of synaptic transmission; GO:0071702 organic substance transport; GO:0030162 regulation of proteolysis; GO:0015849 organic acid transport; GO:0009892 negative regulation of metabolic process; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0006820 anion transport; GO:0007186 G-protein coupled receptor signaling pathway; GO:0045184 establishment of protein localization; GO:1903844 regulation of cellular response to transforming growth factor beta stimulus; GO:0031330 negative regulation of cellular catabolic process; GO:0015711 organic anion transport; GO:0070727 cellular macromolecule localization; GO:0099536 synaptic signaling; GO:0006811 ion transport; GO:0051246 regulation of protein metabolic process; GO:0006835 dicarboxylic acid transport; GO:0051248 negative regulation of protein metabolic process; GO:0006928 movement of cell or subcellular component; GO:0009967 positive regulation of signal transduction; GO:0031647 regulation of protein stability; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0007268 chemical synaptic transmission; GO:0071705 nitrogen compound transport; GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway; GO:0065007 biological regulation; ","GO:0030425 dendrite; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0098862 cluster of actin-based cell projections; GO:0005903 brush border; GO:0005938 cell cortex; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0099568 cytoplasmic region; GO:0044424 intracellular part; GO:0005623 cell; GO:0043197 dendritic spine; GO:0044422 organelle part; GO:0070382 exocytic vesicle; GO:0070062 extracellular exosome; GO:0044309 neuron spine; GO:0008021 synaptic vesicle; GO:0098793 presynapse; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0030139 endocytic vesicle; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0044456 synapse part; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0042995 cell projection; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0005576 extracellular region; GO:0045202 synapse; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0098794 postsynapse; GO:0043198 dendritic shaft; GO:0030133 transport vesicle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0050839 cell adhesion molecule binding; GO:0008092 cytoskeletal protein binding; GO:0042802 identical protein binding; GO:0005102 receptor binding; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0045296 cadherin binding; GO:0046983 protein dimerization activity; GO:0003779 actin binding; GO:0005515 protein binding; GO:0019904 protein domain specific binding; GO:0017022 myosin binding; GO:0030165 PDZ domain binding; ","K20056",null,null,"IPR001478; ","PDZ domain; \r"]
["O14933","Ubiquitin/ISG15-conjugating enzyme E2 L6 OS=Homo sapiens OX=9606 GN=UBE2L6","UBE2L6",17.769,11.126,9.8,1,3,1,0.852,0.826,0.93,1.272,1.024,1.092,1.299,0.0244,"cytoplasm\r","GO:0033554 cellular response to stress; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0032479 regulation of type I interferon production; GO:0044257 cellular protein catabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0006259 DNA metabolic process; GO:0044267 cellular protein metabolic process; GO:0051241 negative regulation of multicellular organismal process; GO:0000731 DNA synthesis involved in DNA repair; GO:0009058 biosynthetic process; GO:0048519 negative regulation of biological process; GO:0001818 negative regulation of cytokine production; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0051239 regulation of multicellular organismal process; GO:0006301 postreplication repair; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0019985 translesion synthesis; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0071897 DNA biosynthetic process; GO:0006508 proteolysis; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0043632 modification-dependent macromolecule catabolic process; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0044265 cellular macromolecule catabolic process; GO:0006950 response to stress; GO:0016567 protein ubiquitination; GO:0019941 modification-dependent protein catabolic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0006974 cellular response to DNA damage stimulus; GO:1901575 organic substance catabolic process; GO:0006281 DNA repair; GO:0050789 regulation of biological process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0090304 nucleic acid metabolic process; GO:0032446 protein modification by small protein conjugation; GO:0030163 protein catabolic process; GO:0009057 macromolecule catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0001817 regulation of cytokine production; GO:0032020 ISG15-protein conjugation; GO:0006464 cellular protein modification process; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:0032480 negative regulation of type I interferon production; GO:0009056 catabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0042296 ISG15 transferase activity; GO:0019787 ubiquitin-like protein transferase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0004842 ubiquitin-protein transferase activity; GO:0043130 ubiquitin binding; GO:0005515 protein binding; GO:0016740 transferase activity; GO:0032182 ubiquitin-like protein binding; ","K04553","UBE2L6; ubiquitin-conjugating enzyme E2 L6 [EC:2.3.2.23]","hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); ","IPR016135; IPR000608; ","Ubiquitin-conjugating enzyme/RWD-like; Ubiquitin-conjugating enzyme E2; \r"]
["O14936","Peripheral plasma membrane protein CASK OS=Homo sapiens OX=9606 GN=CASK","CASK",105.12,14.604,6.5,6,8,6,1.001,1.056,0.951,1.05,0.921,1.007,0.99,0.84,"cytoplasm\r","GO:0044700 single organism signaling; GO:0046710 GDP metabolic process; GO:0065008 regulation of biological quality; GO:0009116 nucleoside metabolic process; GO:0010837 regulation of keratinocyte proliferation; GO:0009891 positive regulation of biosynthetic process; GO:0007269 neurotransmitter secretion; GO:0009185 ribonucleoside diphosphate metabolic process; GO:0044237 cellular metabolic process; GO:0008285 negative regulation of cell proliferation; GO:0022610 biological adhesion; GO:0008152 metabolic process; GO:1901068 guanosine-containing compound metabolic process; GO:0032879 regulation of localization; GO:0050678 regulation of epithelial cell proliferation; GO:0032102 negative regulation of response to external stimulus; GO:0007155 cell adhesion; GO:0019693 ribose phosphate metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0009179 purine ribonucleoside diphosphate metabolic process; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044281 small molecule metabolic process; GO:0043269 regulation of ion transport; GO:0044763 single-organism cellular process; GO:0072521 purine-containing compound metabolic process; GO:0090287 regulation of cellular response to growth factor stimulus; GO:0031323 regulation of cellular metabolic process; GO:0006810 transport; GO:1903506 regulation of nucleic acid-templated transcription; GO:0007267 cell-cell signaling; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0009126 purine nucleoside monophosphate metabolic process; GO:0099643 signal release from synapse; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0001952 regulation of cell-matrix adhesion; GO:0016310 phosphorylation; GO:0007162 negative regulation of cell adhesion; GO:0042127 regulation of cell proliferation; GO:0030001 metal ion transport; GO:0009259 ribonucleotide metabolic process; GO:0044267 cellular protein metabolic process; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0010959 regulation of metal ion transport; GO:0051171 regulation of nitrogen compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0001953 negative regulation of cell-matrix adhesion; GO:0009119 ribonucleoside metabolic process; GO:0051928 positive regulation of calcium ion transport; GO:0051254 positive regulation of RNA metabolic process; GO:0051924 regulation of calcium ion transport; GO:0032101 regulation of response to external stimulus; GO:0023061 signal release; GO:0044238 primary metabolic process; GO:0030155 regulation of cell adhesion; GO:0006163 purine nucleotide metabolic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0043270 positive regulation of ion transport; GO:0061041 regulation of wound healing; GO:0099536 synaptic signaling; GO:0006793 phosphorus metabolic process; GO:0006811 ion transport; GO:0031325 positive regulation of cellular metabolic process; GO:0019637 organophosphate metabolic process; GO:0010810 regulation of cell-substrate adhesion; GO:0031328 positive regulation of cellular biosynthetic process; GO:0043412 macromolecule modification; GO:0051179 localization; GO:0007268 chemical synaptic transmission; GO:1903034 regulation of response to wounding; GO:0070838 divalent metal ion transport; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0001505 regulation of neurotransmitter levels; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009135 purine nucleoside diphosphate metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:2001141 regulation of RNA biosynthetic process; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0098916 anterograde trans-synaptic signaling; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0046037 GMP metabolic process; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0090280 positive regulation of calcium ion import; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:1903035 negative regulation of response to wounding; GO:0051050 positive regulation of transport; GO:0050789 regulation of biological process; GO:0032940 secretion by cell; GO:0019222 regulation of metabolic process; GO:0070509 calcium ion import; GO:1901657 glycosyl compound metabolic process; GO:0050680 negative regulation of epithelial cell proliferation; GO:0036211 protein modification process; GO:0010812 negative regulation of cell-substrate adhesion; GO:0010839 negative regulation of keratinocyte proliferation; GO:0072511 divalent inorganic cation transport; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0099531 presynaptic process involved in chemical synaptic transmission; GO:0071704 organic substance metabolic process; GO:0006468 protein phosphorylation; GO:0006812 cation transport; GO:0006816 calcium ion transport; GO:0090288 negative regulation of cellular response to growth factor stimulus; GO:0099537 trans-synaptic signaling; GO:0034641 cellular nitrogen compound metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0009132 nucleoside diphosphate metabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0051049 regulation of transport; GO:0090279 regulation of calcium ion import; GO:0006807 nitrogen compound metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0061045 negative regulation of wound healing; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0046128 purine ribonucleoside metabolic process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0006836 neurotransmitter transport; GO:0065007 biological regulation; ","GO:0016323 basolateral plasma membrane; GO:0060170 ciliary membrane; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005911 cell-cell junction; GO:0005623 cell; GO:0044420 extracellular matrix component; GO:0042734 presynaptic membrane; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005604 basement membrane; GO:0005856 cytoskeleton; GO:0031974 membrane-enclosed lumen; GO:0005652 nuclear lamina; GO:0005925 focal adhesion; GO:0070013 intracellular organelle lumen; GO:0098590 plasma membrane region; GO:0044441 ciliary part; GO:0098793 presynapse; GO:0005622 intracellular; GO:0044425 membrane part; GO:0044464 cell part; GO:0005912 adherens junction; GO:0097060 synaptic membrane; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0044456 synapse part; GO:0043229 intracellular organelle; GO:0005929 cilium; GO:0042995 cell projection; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0015629 actin cytoskeleton; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0045202 synapse; GO:0043231 intracellular membrane-bounded organelle; GO:0031012 extracellular matrix; GO:0043226 organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0016363 nuclear matrix; GO:0005578 proteinaceous extracellular matrix; GO:0031253 cell projection membrane; GO:0034399 nuclear periphery; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0042043 neurexin family protein binding; GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0005102 receptor binding; GO:0019205 nucleobase-containing compound kinase activity; GO:0005515 protein binding; GO:0004672 protein kinase activity; GO:0016776 phosphotransferase activity, phosphate group as acceptor; GO:0019201 nucleotide kinase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016301 kinase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0005516 calmodulin binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0004385 guanylate kinase activity; GO:0004674 protein serine/threonine kinase activity; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0036094 small molecule binding; ","K06103",null,null,"IPR011511; IPR008144; IPR027417; IPR008145; IPR001478; IPR011009; IPR014775; IPR001452; IPR000719; IPR004172; ","\"Variant SH3 domain; Guanylate kinase-like domain; P-loop containing nucleoside triphosphate hydrolase; Guanylate kinase/L-type calcium channel beta subunit; PDZ domain; Protein kinase-like domain; L27 domain, C-terminal; SH3 domain; Protein kinase domain; L27 domain; \"\r"]
["O14939","Phospholipase D2 OS=Homo sapiens OX=9606 GN=PLD2","PLD2",105.99,1.9819,0.8,1,1,1,0.997,1.243,1.083,0.803,0.899,0.994,0.811,0.0791,"nucleus\r","GO:0044700 single organism signaling; GO:0046486 glycerolipid metabolic process; GO:0051674 localization of cell; GO:0007166 cell surface receptor signaling pathway; GO:0038094 Fc-gamma receptor signaling pathway; GO:0006654 phosphatidic acid biosynthetic process; GO:0008654 phospholipid biosynthetic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0099504 synaptic vesicle cycle; GO:0006909 phagocytosis; GO:0008610 lipid biosynthetic process; GO:0051234 establishment of localization; GO:0048017 inositol lipid-mediated signaling; GO:0099003 vesicle-mediated transport in synapse; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0006650 glycerophospholipid metabolic process; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0006629 lipid metabolic process; GO:0044765 single-organism transport; GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis; GO:0051716 cellular response to stimulus; GO:0051650 establishment of vesicle localization; GO:0048489 synaptic vesicle transport; GO:0044763 single-organism cellular process; GO:0007264 small GTPase mediated signal transduction; GO:0048870 cell motility; GO:0046473 phosphatidic acid metabolic process; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:1902582 single-organism intracellular transport; GO:0050776 regulation of immune response; GO:0090407 organophosphate biosynthetic process; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0050789 regulation of biological process; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:0046474 glycerophospholipid biosynthetic process; GO:0002682 regulation of immune system process; GO:0002431 Fc receptor mediated stimulatory signaling pathway; GO:0040011 locomotion; GO:0051640 organelle localization; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0002252 immune effector process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:1902578 single-organism localization; GO:0051648 vesicle localization; GO:0002757 immune response-activating signal transduction; GO:1902580 single-organism cellular localization; GO:0038093 Fc receptor signaling pathway; GO:0007010 cytoskeleton organization; GO:0050778 positive regulation of immune response; GO:0009987 cellular process; GO:0036465 synaptic vesicle recycling; GO:0002253 activation of immune response; GO:0016042 lipid catabolic process; GO:0044711 single-organism biosynthetic process; GO:0035556 intracellular signal transduction; GO:0044712 single-organism catabolic process; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0006897 endocytosis; GO:0044238 primary metabolic process; GO:0051656 establishment of organelle localization; GO:0048518 positive regulation of biological process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0097480 establishment of synaptic vesicle localization; GO:0051641 cellular localization; GO:0045017 glycerolipid biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0097479 synaptic vesicle localization; GO:0002684 positive regulation of immune system process; GO:0019637 organophosphate metabolic process; GO:0006928 movement of cell or subcellular component; GO:0006644 phospholipid metabolic process; GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0071944 cell periphery; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0045202 synapse; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044432 endoplasmic reticulum part; GO:0044425 membrane part; GO:0044464 cell part; GO:0098793 presynapse; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0005794 Golgi apparatus; GO:0097458 neuron part; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; GO:0044456 synapse part; ","GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity; GO:0043167 ion binding; GO:0004630 phospholipase D activity; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0016298 lipase activity; GO:0042578 phosphoric ester hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0035091 phosphatidylinositol binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0005543 phospholipid binding; GO:0004620 phospholipase activity; GO:0008289 lipid binding; GO:0008081 phosphoric diester hydrolase activity; GO:0043168 anion binding; ","K01115","PLD1_2; phospholipase D1/2 [EC:3.1.4.4]","hsa04666 Fc gamma R-mediated phagocytosis - Homo sapiens (human); hsa05231 Choline metabolism in cancer - Homo sapiens (human); hsa04072 Phospholipase D signaling pathway - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa04912 GnRH signaling pathway - Homo sapiens (human); hsa04071 Sphingolipid signaling pathway - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa04014 Ras signaling pathway - Homo sapiens (human); hsa04024 cAMP signaling pathway - Homo sapiens (human); hsa00564 Glycerophospholipid metabolism - Homo sapiens (human); hsa04144 Endocytosis - Homo sapiens (human); hsa04928 Parathyroid hormone synthesis, secretion and action - Homo sapiens (human); hsa04724 Glutamatergic synapse - Homo sapiens (human); hsa05212 Pancreatic cancer - Homo sapiens (human); hsa00565 Ether lipid metabolism - Homo sapiens (human); ","IPR011993; IPR025202; IPR001736; IPR001683; IPR001849; ","PH domain-like; Phospholipase D-like domain; Phospholipase D/Transphosphatidylase; Phox homologous domain; Pleckstrin homology domain; \r"]
["O14949","Cytochrome b-c1 complex subunit 8 OS=Homo sapiens OX=9606 GN=UQCRQ","UQCRQ",9.9062,10.423,40.2,5,5,5,0.929,1.015,0.958,1.028,0.953,1.068,1.051,0.312,"mitochondria\r","GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0021766 hippocampus development; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0007420 brain development; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0009117 nucleotide metabolic process; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0021761 limbic system development; GO:0021884 forebrain neuron development; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c; GO:0021537 telencephalon development; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0006753 nucleoside phosphate metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0060322 head development; GO:0044765 single-organism transport; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0030901 midbrain development; GO:0098655 cation transmembrane transport; GO:0048699 generation of neurons; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0006119 oxidative phosphorylation; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:0021549 cerebellum development; GO:0021680 cerebellar Purkinje cell layer development; GO:0048513 animal organ development; GO:0021860 pyramidal neuron development; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0007417 central nervous system development; GO:0021536 diencephalon development; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0022900 electron transport chain; GO:0022037 metencephalon development; GO:0021695 cerebellar cortex development; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0048856 anatomical structure development; GO:0098662 inorganic cation transmembrane transport; GO:0021543 pallium development; GO:0044707 single-multicellular organism process; GO:0016310 phosphorylation; GO:0034220 ion transmembrane transport; GO:0021539 subthalamus development; GO:0006725 cellular aromatic compound metabolic process; GO:0021854 hypothalamus development; GO:0042773 ATP synthesis coupled electron transport; GO:0009259 ribonucleotide metabolic process; GO:0022904 respiratory electron transport chain; GO:0021794 thalamus development; GO:0021548 pons development; GO:0048468 cell development; GO:0021953 central nervous system neuron differentiation; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0021879 forebrain neuron differentiation; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0006812 cation transport; GO:0006139 nucleobase-containing compound metabolic process; GO:1902600 hydrogen ion transmembrane transport; GO:1901135 carbohydrate derivative metabolic process; GO:0030900 forebrain development; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009119 ribonucleoside metabolic process; GO:0009987 cellular process; GO:0030902 hindbrain development; GO:0046034 ATP metabolic process; GO:0021859 pyramidal neuron differentiation; GO:0098660 inorganic ion transmembrane transport; GO:0048731 system development; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0045333 cellular respiration; GO:0015992 proton transport; GO:0006818 hydrogen transport; GO:0006163 purine nucleotide metabolic process; GO:0055085 transmembrane transport; GO:0030182 neuron differentiation; GO:0046128 purine ribonucleoside metabolic process; GO:0021954 central nervous system neuron development; GO:0006793 phosphorus metabolic process; GO:0006811 ion transport; GO:0044767 single-organism developmental process; GO:0021872 forebrain generation of neurons; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0051179 localization; GO:0015672 monovalent inorganic cation transport; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:1901564 organonitrogen compound metabolic process; GO:0009123 nucleoside monophosphate metabolic process; ","GO:0016020 membrane; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:1902494 catalytic complex; GO:0044425 membrane part; GO:0005750 mitochondrial respiratory chain complex III; GO:0005622 intracellular; GO:0044464 cell part; GO:0019866 organelle inner membrane; GO:1990351 transporter complex; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0098803 respiratory chain complex; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0070069 cytochrome complex; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:1902495 transmembrane transporter complex; GO:0016021 integral component of membrane; GO:0045275 respiratory chain complex III; GO:0005739 mitochondrion; GO:0005746 mitochondrial respiratory chain; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:1990204 oxidoreductase complex; GO:0031975 envelope; GO:0043234 protein complex; GO:0070469 respiratory chain; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0008121 ubiquinol-cytochrome-c reductase activity; GO:0015075 ion transmembrane transporter activity; GO:0016679 oxidoreductase activity, acting on diphenols and related substances as donors; GO:0003824 catalytic activity; GO:0022892 substrate-specific transporter activity; GO:0015077 monovalent inorganic cation transmembrane transporter activity; GO:0022890 inorganic cation transmembrane transporter activity; GO:0015078 hydrogen ion transmembrane transporter activity; GO:0008324 cation transmembrane transporter activity; GO:0016681 oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor; GO:0022891 substrate-specific transmembrane transporter activity; GO:0022857 transmembrane transporter activity; GO:0005215 transporter activity; GO:0016491 oxidoreductase activity; ","K00418","QCR8; ubiquinol-cytochrome c reductase subunit 8","hsa04260 Cardiac muscle contraction - Homo sapiens (human); hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); "]
["O14964","Hepatocyte growth factor-regulated tyrosine kinase substrate OS=Homo sapiens OX=9606 GN=HGS","HGS",86.191,20.239,8.9,7,8,7,0.955,0.929,1.008,1.042,0.994,1.074,1.075,0.0914,"nucleus\r","GO:0060627 regulation of vesicle-mediated transport; GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:1901185 negative regulation of ERBB signaling pathway; GO:0006623 protein targeting to vacuole; GO:0006914 autophagy; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0008285 negative regulation of cell proliferation; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0008152 metabolic process; GO:0032879 regulation of localization; GO:0036258 multivesicular body assembly; GO:0033365 protein localization to organelle; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0008104 protein localization; GO:1903543 positive regulation of exosomal secretion; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0061462 protein localization to lysosome; GO:0051174 regulation of phosphorus metabolic process; GO:0072657 protein localization to membrane; GO:0045921 positive regulation of exocytosis; GO:0080090 regulation of primary metabolic process; GO:0009894 regulation of catabolic process; GO:0031323 regulation of cellular metabolic process; GO:0072665 protein localization to vacuole; GO:0006810 transport; GO:1902532 negative regulation of intracellular signal transduction; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0051047 positive regulation of secretion; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0042127 regulation of cell proliferation; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0017157 regulation of exocytosis; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:1903541 regulation of exosomal secretion; GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway; GO:0023057 negative regulation of signaling; GO:0046426 negative regulation of JAK-STAT cascade; GO:0010648 negative regulation of cell communication; GO:0010628 positive regulation of gene expression; GO:0051338 regulation of transferase activity; GO:0044248 cellular catabolic process; GO:0042176 regulation of protein catabolic process; GO:0034613 cellular protein localization; GO:0009966 regulation of signal transduction; GO:1904892 regulation of STAT cascade; GO:1902531 regulation of intracellular signal transduction; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0045184 establishment of protein localization; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0043412 macromolecule modification; GO:0051179 localization; GO:0070646 protein modification by small protein removal; GO:0010256 endomembrane system organization; GO:0072594 establishment of protein localization to organelle; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0051046 regulation of secretion; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0072666 establishment of protein localization to vacuole; GO:0009893 positive regulation of metabolic process; GO:0022607 cellular component assembly; GO:0033036 macromolecule localization; GO:0016236 macroautophagy; GO:0010468 regulation of gene expression; GO:0048522 positive regulation of cellular process; GO:0036257 multivesicular body organization; GO:0070647 protein modification by small protein conjugation or removal; GO:0023052 signaling; GO:1903530 regulation of secretion by cell; GO:0051050 positive regulation of transport; GO:0016197 endosomal transport; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:1903532 positive regulation of secretion by cell; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0036211 protein modification process; GO:0043549 regulation of kinase activity; GO:0045859 regulation of protein kinase activity; GO:0046425 regulation of JAK-STAT cascade; GO:0016043 cellular component organization; GO:0043405 regulation of MAP kinase activity; GO:0060255 regulation of macromolecule metabolic process; GO:0010324 membrane invagination; GO:0044087 regulation of cellular component biogenesis; GO:0016579 protein deubiquitination; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0006622 protein targeting to lysosome; GO:0043408 regulation of MAPK cascade; GO:1901184 regulation of ERBB signaling pathway; GO:1904893 negative regulation of STAT cascade; GO:0070925 organelle assembly; GO:0006886 intracellular protein transport; GO:0006508 proteolysis; GO:0009987 cellular process; GO:0007041 lysosomal transport; GO:0051049 regulation of transport; GO:0001932 regulation of protein phosphorylation; GO:0016050 vesicle organization; GO:0048585 negative regulation of response to stimulus; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0070727 cellular macromolecule localization; GO:0051246 regulation of protein metabolic process; GO:0007034 vacuolar transport; GO:0042058 regulation of epidermal growth factor receptor signaling pathway; GO:0007032 endosome organization; GO:0009056 catabolic process; GO:0044089 positive regulation of cellular component biogenesis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0070062 extracellular exosome; GO:0036452 ESCRT complex; GO:0031902 late endosome membrane; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0031901 early endosome membrane; GO:0043227 membrane-bounded organelle; GO:0005771 multivesicular body; GO:0033565 ESCRT-0 complex; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0010008 endosome membrane; GO:0005770 late endosome; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0032585 multivesicular body membrane; GO:0005773 vacuole; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0019904 protein domain specific binding; GO:0005515 protein binding; GO:0005488 binding; GO:0043167 ion binding; ","K12182","HGS; hepatocyte growth factor-regulated tyrosine kinase substrate","hsa04144 Endocytosis - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); ","IPR002014; IPR000306; IPR017455; IPR013083; IPR011011; IPR024641; IPR008942; ","\"VHS domain; FYVE zinc finger; Zinc finger, FYVE-related; Zinc finger, RING/FYVE/PHD-type; Zinc finger, FYVE/PHD-type; Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain; ENTH/VHS; \"\r"]
["O14972","Down syndrome critical region protein 3 OS=Homo sapiens OX=9606 GN=DSCR3","DSCR3",33.01,21.297,10.4,2,3,2,1.128,1.068,1.113,0.826,0.889,0.994,0.819,0.0227,"cytoplasm\r","GO:0045184 establishment of protein localization; GO:0006810 transport; GO:0046907 intracellular transport; GO:0070727 cellular macromolecule localization; GO:0051649 establishment of localization in cell; GO:0006886 intracellular protein transport; GO:0071702 organic substance transport; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0034613 cellular protein localization; GO:0051179 localization; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0051641 cellular localization; ","GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0022892 substrate-specific transporter activity; GO:0008565 protein transporter activity; GO:0005215 transporter activity; ",{"$nulls":3},"IPR014756; ","Immunoglobulin E-set; \r"]
["O14974","Protein phosphatase 1 regulatory subunit 12A OS=Homo sapiens OX=9606 GN=PPP1R12A","PPP1R12A",115.28,49.569,10.7,10,14,10,0.971,1.009,0.914,1.07,1.063,0.999,1.082,0.0931,"nucleus\r","GO:0044700 single organism signaling; GO:0032270 positive regulation of cellular protein metabolic process; GO:0007067 mitotic nuclear division; GO:0009891 positive regulation of biosynthetic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0035303 regulation of dephosphorylation; GO:0044770 cell cycle phase transition; GO:0010562 positive regulation of phosphorus metabolic process; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0070887 cellular response to chemical stimulus; GO:0010468 regulation of gene expression; GO:0051716 cellular response to stimulus; GO:0000278 mitotic cell cycle; GO:0051174 regulation of phosphorus metabolic process; GO:0045937 positive regulation of phosphate metabolic process; GO:0031326 regulation of cellular biosynthetic process; GO:0035507 regulation of myosin-light-chain-phosphatase activity; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0032386 regulation of intracellular transport; GO:0023052 signaling; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0000226 microtubule cytoskeleton organization; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0035306 positive regulation of dephosphorylation; GO:0032516 positive regulation of phosphoprotein phosphatase activity; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0035304 regulation of protein dephosphorylation; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0006464 cellular protein modification process; GO:0044092 negative regulation of molecular function; GO:0035508 positive regulation of myosin-light-chain-phosphatase activity; GO:0019220 regulation of phosphate metabolic process; GO:0036211 protein modification process; GO:0000086 G2/M transition of mitotic cell cycle; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0035690 cellular response to drug; GO:0043666 regulation of phosphoprotein phosphatase activity; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031399 regulation of protein modification process; GO:0048285 organelle fission; GO:0051297 centrosome organization; GO:0044267 cellular protein metabolic process; GO:0050896 response to stimulus; GO:1903047 mitotic cell cycle process; GO:0060341 regulation of cellular localization; GO:0071704 organic substance metabolic process; GO:0010922 positive regulation of phosphatase activity; GO:0042493 response to drug; GO:0051345 positive regulation of hydrolase activity; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0044772 mitotic cell cycle phase transition; GO:0051254 positive regulation of RNA metabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0035307 positive regulation of protein dephosphorylation; GO:0010921 regulation of phosphatase activity; GO:0051049 regulation of transport; GO:0031401 positive regulation of protein modification process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:0006470 protein dephosphorylation; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0007017 microtubule-based process; GO:0016311 dephosphorylation; GO:0030155 regulation of cell adhesion; GO:0043085 positive regulation of catalytic activity; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0051247 positive regulation of protein metabolic process; GO:0046822 regulation of nucleocytoplasmic transport; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0051246 regulation of protein metabolic process; GO:0031023 microtubule organizing center organization; GO:0031325 positive regulation of cellular metabolic process; GO:0000280 nuclear division; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0044839 cell cycle G2/M phase transition; GO:0022402 cell cycle process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0043412 macromolecule modification; GO:0007049 cell cycle; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0030054 cell junction; GO:0030016 myofibril; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0008287 protein serine/threonine phosphatase complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0030018 Z disc; GO:0072357 PTW/PP1 phosphatase complex; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0031674 I band; GO:1903293 phosphatase complex; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0005815 microtubule organizing center; GO:0005654 nucleoplasm; GO:1902494 catalytic complex; GO:0005925 focal adhesion; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0005912 adherens junction; GO:0043292 contractile fiber; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0000776 kinetochore; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0015629 actin cytoskeleton; GO:0099081 supramolecular polymer; GO:0098687 chromosomal region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005813 centrosome; GO:0031672 A band; GO:0000775 chromosome, centromeric region; GO:0030017 sarcomere; GO:0044449 contractile fiber part; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0030234 enzyme regulator activity; GO:0019208 phosphatase regulator activity; GO:0005488 binding; GO:0019901 protein kinase binding; GO:0071889 14-3-3 protein binding; GO:0005515 protein binding; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0019900 kinase binding; GO:0004871 signal transducer activity; GO:0019899 enzyme binding; ","K06270","PPP1R12A; protein phosphatase 1 regulatory subunit 12A","hsa04611 Platelet activation - Homo sapiens (human); hsa04921 Oxytocin signaling pathway - Homo sapiens (human); hsa04024 cAMP signaling pathway - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa04270 Vascular smooth muscle contraction - Homo sapiens (human); ","IPR020683; IPR031775; ","\"Ankyrin repeat-containing domain; cGMP-dependent protein kinase, interacting domain; \"\r"]
["O14976","Cyclin-G-associated kinase OS=Homo sapiens OX=9606 GN=GAK","GAK",143.19,12.726,4.8,7,7,7,1.02,1.068,0.955,1.073,0.948,0.953,0.977,0.673,"plasma membrane\r","GO:0044085 cellular component biogenesis; GO:0090002 establishment of protein localization to plasma membrane; GO:0044237 cellular metabolic process; GO:0099003 vesicle-mediated transport in synapse; GO:0006458 'de novo' protein folding; GO:0008152 metabolic process; GO:0033365 protein localization to organelle; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0008104 protein localization; GO:0044765 single-organism transport; GO:0007399 nervous system development; GO:0048489 synaptic vesicle transport; GO:0072657 protein localization to membrane; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0072319 vesicle uncoating; GO:0007009 plasma membrane organization; GO:0032501 multicellular organismal process; GO:0050768 negative regulation of neurogenesis; GO:0006810 transport; GO:0007030 Golgi organization; GO:0045665 negative regulation of neuron differentiation; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0010721 negative regulation of cell development; GO:0010975 regulation of neuron projection development; GO:0051640 organelle localization; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0016310 phosphorylation; GO:0046907 intracellular transport; GO:0090160 Golgi to lysosome transport; GO:0044267 cellular protein metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0051239 regulation of multicellular organismal process; GO:1990778 protein localization to cell periphery; GO:1902578 single-organism localization; GO:0031345 negative regulation of cell projection organization; GO:0043624 cellular protein complex disassembly; GO:1902580 single-organism cellular localization; GO:0007275 multicellular organism development; GO:0006898 receptor-mediated endocytosis; GO:0034613 cellular protein localization; GO:0090150 establishment of protein localization to membrane; GO:0036465 synaptic vesicle recycling; GO:0006896 Golgi to vacuole transport; GO:0051084 'de novo' posttranslational protein folding; GO:0048731 system development; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0016192 vesicle-mediated transport; GO:0071709 membrane assembly; GO:0032984 macromolecular complex disassembly; GO:0010977 negative regulation of neuron projection development; GO:0051656 establishment of organelle localization; GO:0044238 primary metabolic process; GO:0044091 membrane biogenesis; GO:0097480 establishment of synaptic vesicle localization; GO:0045184 establishment of protein localization; GO:0016191 synaptic vesicle uncoating; GO:0072659 protein localization to plasma membrane; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0097479 synaptic vesicle localization; GO:0061024 membrane organization; GO:0043412 macromolecule modification; GO:0006892 post-Golgi vesicle-mediated transport; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0051093 negative regulation of developmental process; GO:0010256 endomembrane system organization; GO:0072594 establishment of protein localization to organelle; GO:0061077 chaperone-mediated protein folding; GO:0051129 negative regulation of cellular component organization; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0051241 negative regulation of multicellular organismal process; GO:0022008 neurogenesis; GO:0006796 phosphate-containing compound metabolic process; GO:0099504 synaptic vesicle cycle; GO:0051234 establishment of localization; GO:0043241 protein complex disassembly; GO:0006457 protein folding; GO:0051649 establishment of localization in cell; GO:0022607 cellular component assembly; GO:0033036 macromolecule localization; GO:0045596 negative regulation of cell differentiation; GO:0032502 developmental process; GO:0051650 establishment of vesicle localization; GO:0071822 protein complex subunit organization; GO:1902582 single-organism intracellular transport; GO:0050789 regulation of biological process; GO:0045664 regulation of neuron differentiation; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0007029 endoplasmic reticulum organization; GO:2000026 regulation of multicellular organismal development; GO:0016043 cellular component organization; GO:1905224 clathrin-coated pit assembly; GO:0048193 Golgi vesicle transport; GO:0031344 regulation of cell projection organization; GO:0072318 clathrin coat disassembly; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0072583 clathrin-dependent endocytosis; GO:0006468 protein phosphorylation; GO:0051961 negative regulation of nervous system development; GO:0051648 vesicle localization; GO:0016482 cytosolic transport; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0051261 protein depolymerization; GO:0007041 lysosomal transport; GO:0034067 protein localization to Golgi apparatus; GO:0051085 chaperone mediated protein folding requiring cofactor; GO:0072600 establishment of protein localization to Golgi; GO:0044802 single-organism membrane organization; GO:0006897 endocytosis; GO:0043933 macromolecular complex subunit organization; GO:0051641 cellular localization; GO:0048488 synaptic vesicle endocytosis; GO:0070727 cellular macromolecule localization; GO:0007034 vacuolar transport; GO:0044767 single-organism developmental process; GO:0022411 cellular component disassembly; GO:0051128 regulation of cellular component organization; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0050767 regulation of neurogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0070161 anchoring junction; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0045202 synapse; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:0048471 perinuclear region of cytoplasm; GO:0030055 cell-substrate junction; GO:0005794 Golgi apparatus; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0005924 cell-substrate adherens junction; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0051087 chaperone binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0004672 protein kinase activity; GO:0030332 cyclin binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016301 kinase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0004674 protein serine/threonine kinase activity; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K08855",null,null,"IPR029021; IPR029023; IPR000719; IPR014020; IPR001623; IPR000008; IPR011009; ","\"Protein-tyrosine phosphatase-like; Tensin phosphatase, lipid phosphatase domain; Protein kinase domain; Tensin phosphatase, C2 domain; DnaJ domain; C2 domain; Protein kinase-like domain; \"\r"]
["O14979","Heterogeneous nuclear ribonucleoprotein D-like OS=Homo sapiens OX=9606 GN=HNRNPDL","HNRNPDL",46.437,46.22,19.3,9,19,8,0.881,0.93,0.905,1.064,1.043,1.106,1.183,0.00194,"nucleus\r","GO:0050794 regulation of cellular process; GO:0006725 cellular aromatic compound metabolic process; GO:0097659 nucleic acid-templated transcription; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006396 RNA processing; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0006355 regulation of transcription, DNA-templated; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:0031323 regulation of cellular metabolic process; GO:1901576 organic substance biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0010467 gene expression; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005681 spliceosomal complex; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:1990904 ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0030529 intracellular ribonucleoprotein complex; GO:0043230 extracellular organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0008143 poly(A) binding; GO:0003677 DNA binding; GO:0003723 RNA binding; GO:1901265 nucleoside phosphate binding; GO:0003690 double-stranded DNA binding; GO:0003697 single-stranded DNA binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0070717 poly-purine tract binding; GO:0003727 single-stranded RNA binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0034046 poly(G) binding; GO:0036094 small molecule binding; ","K13044",null,null,"IPR000504; IPR012677; ","RNA recognition motif domain; Nucleotide-binding alpha-beta plait domain; \r"]
["O14980","Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1","XPO1",123.38,169.01,25.5,22,31,22,0.968,0.943,1.008,1.017,1.032,1.015,1.05,0.0719,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0050658 RNA transport; GO:0065008 regulation of biological quality; GO:0022613 ribonucleoprotein complex biogenesis; GO:0010608 posttranscriptional regulation of gene expression; GO:0051169 nuclear transport; GO:0071428 rRNA-containing ribonucleoprotein complex export from nucleus; GO:0010564 regulation of cell cycle process; GO:0015031 protein transport; GO:1902583 multi-organism intracellular transport; GO:0032879 regulation of localization; GO:0010824 regulation of centrosome duplication; GO:0015931 nucleobase-containing compound transport; GO:0033365 protein localization to organelle; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0051493 regulation of cytoskeleton organization; GO:0075733 intracellular transport of virus; GO:0044419 interspecies interaction between organisms; GO:0008104 protein localization; GO:0007059 chromosome segregation; GO:0080090 regulation of primary metabolic process; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0000122 negative regulation of transcription from RNA polymerase II promoter; GO:0042254 ribosome biogenesis; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0031323 regulation of cellular metabolic process; GO:0006611 protein export from nucleus; GO:0051704 multi-organism process; GO:0032886 regulation of microtubule-based process; GO:0006810 transport; GO:1903506 regulation of nucleic acid-templated transcription; GO:0046825 regulation of protein export from nucleus; GO:0051223 regulation of protein transport; GO:0006913 nucleocytoplasmic transport; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0046605 regulation of centrosome cycle; GO:0051640 organelle localization; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0033750 ribosome localization; GO:0051028 mRNA transport; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0051236 establishment of RNA localization; GO:0060341 regulation of cellular localization; GO:0043487 regulation of RNA stability; GO:0045892 negative regulation of transcription, DNA-templated; GO:0042493 response to drug; GO:0000056 ribosomal small subunit export from nucleus; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0032880 regulation of protein localization; GO:0042176 regulation of protein catabolic process; GO:0034613 cellular protein localization; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0046794 transport of virus; GO:0006403 RNA localization; GO:0006405 RNA export from nucleus; GO:0071702 organic substance transport; GO:0051656 establishment of organelle localization; GO:0009892 negative regulation of metabolic process; GO:0044766 multi-organism transport; GO:0045184 establishment of protein localization; GO:0009890 negative regulation of biosynthetic process; GO:0051276 chromosome organization; GO:0046822 regulation of nucleocytoplasmic transport; GO:0006996 organelle organization; GO:0098813 nuclear chromosome segregation; GO:0007062 sister chromatid cohesion; GO:0051179 localization; GO:1903827 regulation of cellular protein localization; GO:0000055 ribosomal large subunit export from nucleus; GO:0033753 establishment of ribosome localization; GO:0044699 single-organism process; GO:0051168 nuclear export; GO:1902581 multi-organism cellular localization; GO:0044764 multi-organism cellular process; GO:0051253 negative regulation of RNA metabolic process; GO:0051234 establishment of localization; GO:2001141 regulation of RNA biosynthetic process; GO:0000819 sister chromatid segregation; GO:0051649 establishment of localization in cell; GO:0050657 nucleic acid transport; GO:0033036 macromolecule localization; GO:0051726 regulation of cell cycle; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0032386 regulation of intracellular transport; GO:0010605 negative regulation of macromolecule metabolic process; GO:0071166 ribonucleoprotein complex localization; GO:1902589 single-organism organelle organization; GO:0000054 ribosomal subunit export from nucleus; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:1902679 negative regulation of RNA biosynthetic process; GO:0019222 regulation of metabolic process; GO:1902579 multi-organism localization; GO:0016043 cellular component organization; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0070201 regulation of establishment of protein localization; GO:0016032 viral process; GO:0006886 intracellular protein transport; GO:0009987 cellular process; GO:0033157 regulation of intracellular protein transport; GO:0070507 regulation of microtubule cytoskeleton organization; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0051049 regulation of transport; GO:0033043 regulation of organelle organization; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0043488 regulation of mRNA stability; GO:0051641 cellular localization; GO:0070727 cellular macromolecule localization; GO:0071426 ribonucleoprotein complex export from nucleus; GO:0051246 regulation of protein metabolic process; GO:0022402 cell cycle process; GO:0051128 regulation of cellular component organization; GO:0031327 negative regulation of cellular biosynthetic process; GO:0034504 protein localization to nucleus; GO:0007049 cell cycle; GO:0071705 nitrogen compound transport; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0015030 Cajal body; GO:0043228 non-membrane-bounded organelle; GO:0044427 chromosomal part; GO:0031974 membrane-enclosed lumen; GO:0031965 nuclear membrane; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005642 annulate lamellae; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0098805 whole membrane; GO:0098589 membrane region; GO:0043227 membrane-bounded organelle; GO:0000776 kinetochore; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005635 nuclear envelope; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0098687 chromosomal region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0031975 envelope; GO:0000775 chromosome, centromeric region; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0031267 small GTPase binding; GO:0003723 RNA binding; GO:0005487 nucleocytoplasmic transporter activity; GO:0008565 protein transporter activity; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0005049 nuclear export signal receptor activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0017016 Ras GTPase binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0008536 Ran GTPase binding; GO:0019904 protein domain specific binding; GO:0051020 GTPase binding; GO:0019899 enzyme binding; GO:0005215 transporter activity; ","K14290","XPO1; exportin-1","hsa05166 HTLV-I infection - Homo sapiens (human); hsa03008 Ribosome biogenesis in eukaryotes - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); hsa03013 RNA transport - Homo sapiens (human); hsa05164 Influenza A - Homo sapiens (human); ","IPR001494; IPR014877; IPR013598; IPR011989; IPR016024; ","\"Importin-beta, N-terminal domain; CRM1 C-terminal domain; Exportin-1/Importin-beta-like; Armadillo-like helical; Armadillo-type fold; \"\r"]
["O14981","TATA-binding protein-associated factor 172 OS=Homo sapiens OX=9606 GN=BTAF1","BTAF1",206.89,2.2359,0.5,1,1,1,1.08,0.95,0.912,1.14,0.967,0.965,1.044,0.6,"plasma membrane\r","GO:0050794 regulation of cellular process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0051253 negative regulation of RNA metabolic process; GO:0045892 negative regulation of transcription, DNA-templated; GO:2001141 regulation of RNA biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0035562 negative regulation of chromatin binding; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0010468 regulation of gene expression; GO:0006355 regulation of transcription, DNA-templated; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0010629 negative regulation of gene expression; GO:0051098 regulation of binding; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0009892 negative regulation of metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0035561 regulation of chromatin binding; GO:0009890 negative regulation of biosynthetic process; GO:0050789 regulation of biological process; GO:0051100 negative regulation of binding; GO:1902679 negative regulation of RNA biosynthetic process; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0031327 negative regulation of cellular biosynthetic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0065007 biological regulation; ","GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0044422 organelle part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0003700 transcription factor activity, sequence-specific DNA binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0001071 nucleic acid binding transcription factor activity; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003677 DNA binding; GO:0005524 ATP binding; GO:0004386 helicase activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003676 nucleic acid binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; ","K15192",null,null,"IPR011989; IPR014001; IPR027417; IPR001650; IPR016024; IPR022707; IPR000330; ","\"Armadillo-like helical; Helicase superfamily 1/2, ATP-binding domain; P-loop containing nucleoside triphosphate hydrolase; Helicase, C-terminal; Armadillo-type fold; Domain of unknown function DUF3535; SNF2-related, N-terminal domain; \"\r"]
["O15020","Spectrin beta chain, non-erythrocytic 2 OS=Homo sapiens OX=9606 GN=SPTBN2","SPTBN2",271.32,250.8,21.9,47,68,37,1.027,1.02,0.996,1.002,1.006,0.984,0.983,0.217,"cytoplasm\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0007420 brain development; GO:0032989 cellular component morphogenesis; GO:0030832 regulation of actin filament length; GO:0044237 cellular metabolic process; GO:0007610 behavior; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0032535 regulation of cellular component size; GO:0044093 positive regulation of molecular function; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0051493 regulation of cytoskeleton organization; GO:0031333 negative regulation of protein complex assembly; GO:0021587 cerebellum morphogenesis; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0021575 hindbrain morphogenesis; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0048812 neuron projection morphogenesis; GO:0006935 chemotaxis; GO:0032501 multicellular organismal process; GO:0021549 cerebellum development; GO:0000902 cell morphogenesis; GO:0006810 transport; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0000165 MAPK cascade; GO:0048513 animal organ development; GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; GO:0051336 regulation of hydrolase activity; GO:0007417 central nervous system development; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0021696 cerebellar cortex morphogenesis; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0030837 negative regulation of actin filament polymerization; GO:0042330 taxis; GO:0021695 cerebellar cortex development; GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II; GO:0030834 regulation of actin filament depolymerization; GO:0044708 single-organism behavior; GO:1902903 regulation of supramolecular fiber organization; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0016310 phosphorylation; GO:0044707 single-multicellular organism process; GO:0032956 regulation of actin cytoskeleton organization; GO:0044267 cellular protein metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0009653 anatomical structure morphogenesis; GO:0051345 positive regulation of hydrolase activity; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0007409 axonogenesis; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0030534 adult behavior; GO:0030902 hindbrain development; GO:0023014 signal transduction by protein phosphorylation; GO:0043547 positive regulation of GTPase activity; GO:0048731 system development; GO:1901879 regulation of protein depolymerization; GO:0016192 vesicle-mediated transport; GO:0007416 synapse assembly; GO:0002376 immune system process; GO:0032970 regulation of actin filament-based process; GO:0044238 primary metabolic process; GO:0050808 synapse organization; GO:0008064 regulation of actin polymerization or depolymerization; GO:0030182 neuron differentiation; GO:0006793 phosphorus metabolic process; GO:0097485 neuron projection guidance; GO:0006996 organelle organization; GO:0006928 movement of cell or subcellular component; GO:0048589 developmental growth; GO:0043412 macromolecule modification; GO:0051179 localization; GO:0040007 growth; GO:0030833 regulation of actin filament polymerization; GO:0030835 negative regulation of actin filament depolymerization; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0051129 negative regulation of cellular component organization; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0051693 actin filament capping; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0032990 cell part morphogenesis; GO:0048858 cell projection morphogenesis; GO:0032271 regulation of protein polymerization; GO:0060322 head development; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0032502 developmental process; GO:0051494 negative regulation of cytoskeleton organization; GO:0048002 antigen processing and presentation of peptide antigen; GO:0023052 signaling; GO:0002495 antigen processing and presentation of peptide antigen via MHC class II; GO:0021680 cerebellar Purkinje cell layer development; GO:0010639 negative regulation of organelle organization; GO:0042221 response to chemical; GO:0043254 regulation of protein complex assembly; GO:0050789 regulation of biological process; GO:0030030 cell projection organization; GO:0043242 negative regulation of protein complex disassembly; GO:1902904 negative regulation of supramolecular fiber organization; GO:0043087 regulation of GTPase activity; GO:0065009 regulation of molecular function; GO:0022037 metencephalon development; GO:0040011 locomotion; GO:0043244 regulation of protein complex disassembly; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0016043 cellular component organization; GO:0048193 Golgi vesicle transport; GO:0044087 regulation of cellular component biogenesis; GO:0050896 response to stimulus; GO:0007411 axon guidance; GO:0048468 cell development; GO:0000904 cell morphogenesis involved in differentiation; GO:0071704 organic substance metabolic process; GO:1901880 negative regulation of protein depolymerization; GO:0030154 cell differentiation; GO:0006468 protein phosphorylation; GO:0035264 multicellular organism growth; GO:0021692 cerebellar Purkinje cell layer morphogenesis; GO:0009987 cellular process; GO:0035556 intracellular signal transduction; GO:0033043 regulation of organelle organization; GO:0031175 neuron projection development; GO:0051641 cellular localization; GO:0043085 positive regulation of catalytic activity; GO:0061564 axon development; GO:0019882 antigen processing and presentation; GO:0044767 single-organism developmental process; GO:0090066 regulation of anatomical structure size; GO:0051128 regulation of cellular component organization; GO:0032272 negative regulation of protein polymerization; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005938 cell cortex; GO:0016324 apical plasma membrane; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0099568 cytoplasmic region; GO:0030863 cortical cytoskeleton; GO:0043025 neuronal cell body; GO:0030864 cortical actin cytoskeleton; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0098590 plasma membrane region; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0008091 spectrin; GO:0097458 neuron part; GO:0045177 apical part of cell; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0005829 cytosol; GO:0015629 actin cytoskeleton; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0044459 plasma membrane part; GO:0044448 cell cortex part; GO:0044297 cell body; GO:0044444 cytoplasmic part; ","GO:0005085 guanyl-nucleotide exchange factor activity; GO:0043167 ion binding; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0050839 cell adhesion molecule binding; GO:0008092 cytoskeletal protein binding; GO:0005200 structural constituent of cytoskeleton; GO:0005488 binding; GO:0045296 cadherin binding; GO:0005543 phospholipid binding; GO:0008289 lipid binding; GO:0003779 actin binding; GO:0043168 anion binding; GO:0005088 Ras guanyl-nucleotide exchange factor activity; GO:0005198 structural molecule activity; ","K06115",null,null,"IPR001605; IPR011993; IPR001715; IPR001849; ","\"Pleckstrin homology domain, spectrin-type; PH domain-like; Calponin homology domain; Pleckstrin homology domain; \"\r"]
["O15027","Protein transport protein Sec16A OS=Homo sapiens OX=9606 GN=SEC16A","SEC16A",233.51,3.2332,1,2,2,2,0.924,1.059,0.954,0.919,1.043,1.104,1.044,0.572,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0051640 organelle localization; GO:0016043 cellular component organization; GO:0006901 vesicle coating; GO:0046907 intracellular transport; GO:0044707 single-multicellular organism process; GO:0010256 endomembrane system organization; GO:0048207 vesicle targeting, rough ER to cis-Golgi; GO:0048208 COPII vesicle coating; GO:0007420 brain development; GO:0048193 Golgi vesicle transport; GO:0044699 single-organism process; GO:0006903 vesicle targeting; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0048857 neural nucleus development; GO:0021762 substantia nigra development; GO:0051649 establishment of localization in cell; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0048199 vesicle targeting, to, from or within Golgi; GO:0051648 vesicle localization; GO:0060322 head development; GO:0007275 multicellular organism development; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0051650 establishment of vesicle localization; GO:0030901 midbrain development; GO:0071822 protein complex subunit organization; GO:0090114 COPII-coated vesicle budding; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0016050 vesicle organization; GO:0071702 organic substance transport; GO:0051656 establishment of organelle localization; GO:0032501 multicellular organismal process; GO:0051641 cellular localization; GO:0043933 macromolecular complex subunit organization; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:0048513 animal organ development; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0007417 central nervous system development; GO:0006900 membrane budding; GO:0061024 membrane organization; GO:0070271 protein complex biogenesis; GO:0051179 localization; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0048856 anatomical structure development; GO:0007029 endoplasmic reticulum organization; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0098588 bounding membrane of organelle; GO:0031090 organelle membrane; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044432 endoplasmic reticulum part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0044431 Golgi apparatus part; GO:0005794 Golgi apparatus; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ","K20353",null,null,"IPR024340; IPR024298; ","\"Sec16, central conserved domain; Ancestral coatomer element 1, Sec16/Sec31; \"\r"]
["O15031","Plexin-B2 OS=Homo sapiens OX=9606 GN=PLXNB2","PLXNB2",205.12,27.359,5,8,10,8,0.971,1.016,0.999,0.95,1.046,1.038,1.016,0.675,"plasma membrane\r","GO:0001841 neural tube formation; GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0045666 positive regulation of neuron differentiation; GO:0007166 cell surface receptor signaling pathway; GO:0035148 tube formation; GO:0043009 chordate embryonic development; GO:0007420 brain development; GO:0048869 cellular developmental process; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0051130 positive regulation of cellular component organization; GO:0022610 biological adhesion; GO:0061351 neural precursor cell proliferation; GO:0048729 tissue morphogenesis; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0008360 regulation of cell shape; GO:0007155 cell adhesion; GO:0060322 head development; GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules; GO:0009790 embryo development; GO:0010720 positive regulation of cell development; GO:0048598 embryonic morphogenesis; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0035295 tube development; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0009888 tissue development; GO:0080090 regulation of primary metabolic process; GO:0031346 positive regulation of cell projection organization; GO:0048699 generation of neurons; GO:0035239 tube morphogenesis; GO:0098609 cell-cell adhesion; GO:0051962 positive regulation of nervous system development; GO:0007405 neuroblast proliferation; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0048513 animal organ development; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:0045664 regulation of neuron differentiation; GO:0050790 regulation of catalytic activity; GO:0007417 central nervous system development; GO:0043087 regulation of GTPase activity; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0051094 positive regulation of developmental process; GO:0048856 anatomical structure development; GO:0010975 regulation of neuron projection development; GO:2000026 regulation of multicellular organismal development; GO:0050794 regulation of cellular process; GO:0002009 morphogenesis of an epithelium; GO:0044707 single-multicellular organism process; GO:0007162 negative regulation of cell adhesion; GO:0060255 regulation of macromolecule metabolic process; GO:0031399 regulation of protein modification process; GO:0010770 positive regulation of cell morphogenesis involved in differentiation; GO:0031344 regulation of cell projection organization; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0021915 neural tube development; GO:0050896 response to stimulus; GO:0072089 stem cell proliferation; GO:0051239 regulation of multicellular organismal process; GO:0045597 positive regulation of cell differentiation; GO:0072175 epithelial tube formation; GO:0009653 anatomical structure morphogenesis; GO:0060606 tube closure; GO:0030154 cell differentiation; GO:0050772 positive regulation of axonogenesis; GO:2000145 regulation of cell motility; GO:0016331 morphogenesis of embryonic epithelium; GO:0007275 multicellular organism development; GO:0001843 neural tube closure; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0060562 epithelial tube morphogenesis; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0009792 embryo development ending in birth or egg hatching; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0001932 regulation of protein phosphorylation; GO:0030334 regulation of cell migration; GO:0008283 cell proliferation; GO:0048518 positive regulation of biological process; GO:0050770 regulation of axonogenesis; GO:0030155 regulation of cell adhesion; GO:0014020 primary neural tube formation; GO:0001838 embryonic epithelial tube formation; GO:0010976 positive regulation of neuron projection development; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:2001222 regulation of neuron migration; GO:0050769 positive regulation of neurogenesis; GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules; GO:0051128 regulation of cellular component organization; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:0040012 regulation of locomotion; GO:0050793 regulation of developmental process; GO:0022604 regulation of cell morphogenesis; GO:0071526 semaphorin-plexin signaling pathway; GO:0050767 regulation of neurogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031226 intrinsic component of plasma membrane; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0044459 plasma membrane part; GO:0044464 cell part; GO:0044425 membrane part; GO:1903561 extracellular vesicle; GO:0009986 cell surface; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0038023 signaling receptor activity; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0005488 binding; GO:0017154 semaphorin receptor activity; GO:0005515 protein binding; GO:0004888 transmembrane signaling receptor activity; GO:0004871 signal transducer activity; GO:0099600 transmembrane receptor activity; ","K06821","PLXNB; plexin B","hsa04360 Axon guidance - Homo sapiens (human); ","IPR013548; IPR001936; IPR013783; IPR014756; IPR015943; IPR016201; IPR002909; IPR008936; IPR001627; ","\"Plexin, cytoplasmic RasGAP domain; Ras GTPase-activating protein; Immunoglobulin-like fold; Immunoglobulin E-set; WD40/YVTN repeat-like-containing domain; PSI domain; IPT domain; Rho GTPase activation protein; Sema domain; \"\r"]
["O15061","Synemin OS=Homo sapiens OX=9606 GN=SYNM","SYNM",172.77,45.571,9.7,15,17,15,1.071,1.029,1.047,0.912,0.92,0.928,0.877,0.000483,"nucleus\r","GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0003012 muscle system process; GO:0003008 system process; GO:0045104 intermediate filament cytoskeleton organization; GO:0045103 intermediate filament-based process; GO:0050879 multicellular organismal movement; GO:0044763 single-organism cellular process; GO:0006941 striated muscle contraction; GO:0044699 single-organism process; GO:0032501 multicellular organismal process; GO:0003010 voluntary skeletal muscle contraction; GO:0003009 skeletal muscle contraction; GO:1902589 single-organism organelle organization; GO:0006936 muscle contraction; GO:0006996 organelle organization; GO:0031443 fast-twitch skeletal muscle fiber contraction; GO:0050881 musculoskeletal movement; GO:0014721 twitch skeletal muscle contraction; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0030016 myofibril; GO:0005737 cytoplasm; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:0043292 contractile fiber; GO:0097458 neuron part; GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0060053 neurofilament cytoskeleton; GO:0005886 plasma membrane; GO:0099081 supramolecular polymer; GO:0043226 organelle; GO:0045111 intermediate filament cytoskeleton; GO:0043034 costamere; GO:0005882 intermediate filament; GO:0044449 contractile fiber part; GO:0042383 sarcolemma; GO:0044444 cytoplasmic part; ","GO:0008092 cytoskeletal protein binding; GO:0019215 intermediate filament binding; GO:0005200 structural constituent of cytoskeleton; GO:0017166 vinculin binding; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0005515 protein binding; GO:0005198 structural molecule activity; GO:0008307 structural constituent of muscle; GO:0032403 protein complex binding; ","K10376"]
["O15075","Serine/threonine-protein kinase DCLK1 OS=Homo sapiens OX=9606 GN=DCLK1","DCLK1",82.223,78.426,14.6,9,12,9,1.117,1.11,1.106,0.918,0.873,0.88,0.801,1.56E-4,"cytoplasm\r","GO:0044700 single organism signaling; GO:0051674 localization of cell; GO:0018209 peptidyl-serine modification; GO:0007420 brain development; GO:0048869 cellular developmental process; GO:0048666 neuron development; GO:0032989 cellular component morphogenesis; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0009607 response to biotic stimulus; GO:0051234 establishment of localization; GO:0009605 response to external stimulus; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0007154 cell communication; GO:0032990 cell part morphogenesis; GO:0032879 regulation of localization; GO:0048858 cell projection morphogenesis; GO:0001764 neuron migration; GO:0018105 peptidyl-serine phosphorylation; GO:0060322 head development; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0044419 interspecies interaction between organisms; GO:1900181 negative regulation of protein localization to nucleus; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0048675 axon extension; GO:1903828 negative regulation of cellular protein localization; GO:0016049 cell growth; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0048812 neuron projection morphogenesis; GO:0048870 cell motility; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0016197 endosomal transport; GO:0006810 transport; GO:0000902 cell morphogenesis; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0030030 cell projection organization; GO:0007417 central nervous system development; GO:0048813 dendrite morphogenesis; GO:1900180 regulation of protein localization to nucleus; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0040011 locomotion; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0009615 response to virus; GO:0050794 regulation of cellular process; GO:0016477 cell migration; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0016310 phosphorylation; GO:0016358 dendrite development; GO:0018210 peptidyl-threonine modification; GO:0044267 cellular protein metabolic process; GO:1990138 neuron projection extension; GO:0043207 response to external biotic stimulus; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0021953 central nervous system neuron differentiation; GO:0048468 cell development; GO:0060341 regulation of cellular localization; GO:0071704 organic substance metabolic process; GO:0000904 cell morphogenesis involved in differentiation; GO:0021955 central nervous system neuron axonogenesis; GO:0009653 anatomical structure morphogenesis; GO:0030154 cell differentiation; GO:0006468 protein phosphorylation; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0016032 viral process; GO:0007409 axonogenesis; GO:0018107 peptidyl-threonine phosphorylation; GO:0030900 forebrain development; GO:0032880 regulation of protein localization; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0035556 intracellular signal transduction; GO:0048731 system development; GO:0060560 developmental growth involved in morphogenesis; GO:0031175 neuron projection development; GO:0044238 primary metabolic process; GO:0018193 peptidyl-amino acid modification; GO:0061564 axon development; GO:0030182 neuron differentiation; GO:0021954 central nervous system neuron development; GO:0006793 phosphorus metabolic process; GO:0044767 single-organism developmental process; GO:0048588 developmental cell growth; GO:0006928 movement of cell or subcellular component; GO:0021952 central nervous system projection neuron axonogenesis; GO:0043412 macromolecule modification; GO:0048589 developmental growth; GO:0051179 localization; GO:0040007 growth; GO:1903827 regulation of cellular protein localization; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0031226 intrinsic component of plasma membrane; GO:0071944 cell periphery; GO:0031224 intrinsic component of membrane; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0032279 asymmetric synapse; GO:0045202 synapse; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0098794 postsynapse; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0014069 postsynaptic density; GO:0099572 postsynaptic specialization; GO:0098984 neuron to neuron synapse; GO:0044456 synapse part; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0004672 protein kinase activity; GO:0000166 nucleotide binding; GO:0004871 signal transducer activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0005057 signal transducer activity, downstream of receptor; GO:0097367 carbohydrate derivative binding; GO:0016301 kinase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0004674 protein serine/threonine kinase activity; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0016740 transferase activity; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K08805",null,null,"IPR000719; IPR003533; IPR011009; ","Protein kinase domain; Doublecortin domain; Protein kinase-like domain; \r"]
["O15085","Rho guanine nucleotide exchange factor 11 OS=Homo sapiens OX=9606 GN=ARHGEF11","ARHGEF11",167.7,2.8533,0.6,1,2,1,0.909,1.063,0.999,0.972,1.102,0.961,1.022,0.752,"nucleus\r","GO:0044700 single organism signaling; GO:0003012 muscle system process; GO:0010941 regulation of cell death; GO:0023051 regulation of signaling; GO:0009891 positive regulation of biosynthetic process; GO:0044699 single-organism process; GO:0001558 regulation of cell growth; GO:2001141 regulation of RNA biosynthetic process; GO:0030036 actin cytoskeleton organization; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0044093 positive regulation of molecular function; GO:0007266 Rho protein signal transduction; GO:0051056 regulation of small GTPase mediated signal transduction; GO:0051716 cellular response to stimulus; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044763 single-organism cellular process; GO:0006941 striated muscle contraction; GO:0048522 positive regulation of cellular process; GO:0007264 small GTPase mediated signal transduction; GO:0007163 establishment or maintenance of cell polarity; GO:0023052 signaling; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0010942 positive regulation of cell death; GO:1902589 single-organism organelle organization; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0051301 cell division; GO:0007265 Ras protein signal transduction; GO:0043068 positive regulation of programmed cell death; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0040008 regulation of growth; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0043067 regulation of programmed cell death; GO:0043065 positive regulation of apoptotic process; GO:0046578 regulation of Ras protein signal transduction; GO:0050896 response to stimulus; GO:0006936 muscle contraction; GO:0000910 cytokinesis; GO:0051345 positive regulation of hydrolase activity; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0030010 establishment of cell polarity; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0007010 cytoskeleton organization; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:0051254 positive regulation of RNA metabolic process; GO:1902531 regulation of intracellular signal transduction; GO:0006355 regulation of transcription, DNA-templated; GO:0003008 system process; GO:0035556 intracellular signal transduction; GO:0043547 positive regulation of GTPase activity; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0043085 positive regulation of catalytic activity; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0007186 G-protein coupled receptor signaling pathway; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0031325 positive regulation of cellular metabolic process; GO:0006928 movement of cell or subcellular component; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0022402 cell cycle process; GO:0051128 regulation of cellular component organization; GO:0031328 positive regulation of cellular biosynthetic process; GO:0035023 regulation of Rho protein signal transduction; GO:0007049 cell cycle; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0044444 cytoplasmic part; ","GO:0030234 enzyme regulator activity; GO:0005102 receptor binding; GO:0005085 guanyl-nucleotide exchange factor activity; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0005488 binding; GO:0030695 GTPase regulator activity; GO:0005088 Ras guanyl-nucleotide exchange factor activity; GO:0005515 protein binding; GO:0001664 G-protein coupled receptor binding; GO:0098772 molecular function regulator; GO:0008047 enzyme activator activity; GO:0005089 Rho guanyl-nucleotide exchange factor activity; GO:0005096 GTPase activator activity; ","K12331","ARHGEF11; Rho guanine nucleotide exchange factor 11","hsa05200 Pathways in cancer - Homo sapiens (human); hsa04928 Parathyroid hormone synthesis, secretion and action - Homo sapiens (human); hsa04270 Vascular smooth muscle contraction - Homo sapiens (human); ","IPR016137; IPR015212; IPR011993; IPR001478; IPR000219; IPR001849; ","RGS domain; Regulator of G protein signalling-like domain; PH domain-like; PDZ domain; Dbl homology (DH) domain; Pleckstrin homology domain; \r"]
["O15116","U6 snRNA-associated Sm-like protein LSm1 OS=Homo sapiens OX=9606 GN=LSM1","LSM1",15.179,9.513,12,1,1,1,0.54,1.397,2.628,0.54,0.466,0.464,0.322,0.178,"cytoplasm\r","GO:0051093 negative regulation of developmental process; GO:0048869 cellular developmental process; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0051241 negative regulation of multicellular organismal process; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA; GO:1901361 organic cyclic compound catabolic process; GO:0043170 macromolecule metabolic process; GO:0045596 negative regulation of cell differentiation; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0006396 RNA processing; GO:0008334 histone mRNA metabolic process; GO:0010468 regulation of gene expression; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic; GO:0071044 histone mRNA catabolic process; GO:0032501 multicellular organismal process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0050768 negative regulation of neurogenesis; GO:0006397 mRNA processing; GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; GO:0006401 RNA catabolic process; GO:0016070 RNA metabolic process; GO:0019439 aromatic compound catabolic process; GO:1901575 organic substance catabolic process; GO:0050789 regulation of biological process; GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; GO:0090304 nucleic acid metabolic process; GO:0045664 regulation of neuron differentiation; GO:0006402 mRNA catabolic process; GO:0098727 maintenance of cell number; GO:0045665 negative regulation of neuron differentiation; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0010721 negative regulation of cell development; GO:0048856 anatomical structure development; GO:0016071 mRNA metabolic process; GO:2000026 regulation of multicellular organismal development; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0051239 regulation of multicellular organismal process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0030154 cell differentiation; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0051961 negative regulation of nervous system development; GO:0000375 RNA splicing, via transesterification reactions; GO:0044248 cellular catabolic process; GO:0019827 stem cell population maintenance; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0008380 RNA splicing; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0045595 regulation of cell differentiation; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0048731 system development; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0044767 single-organism developmental process; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0050793 regulation of developmental process; GO:0009056 catabolic process; GO:0050767 regulation of neurogenesis; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0030425 dendrite; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0000932 P-body; GO:0005737 cytoplasm; GO:0043025 neuronal cell body; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0043228 non-membrane-bounded organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0030424 axon; GO:0043226 organelle; GO:0005634 nucleus; GO:0036477 somatodendritic compartment; GO:0044464 cell part; GO:0005622 intracellular; GO:0035770 ribonucleoprotein granule; GO:0043005 neuron projection; GO:0044297 cell body; GO:1990904 ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0030529 intracellular ribonucleoprotein complex; GO:0097458 neuron part; GO:1990124 messenger ribonucleoprotein complex; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003729 mRNA binding; GO:0003723 RNA binding; GO:0000339 RNA cap binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0036002 pre-mRNA binding; GO:0005515 protein binding; ","K12620","LSM1; U6 snRNA-associated Sm-like protein LSm1","hsa03018 RNA degradation - Homo sapiens (human); ","IPR001163; IPR034104; IPR010920; ","\"LSM domain, eukaryotic/archaea-type; Sm-like protein Lsm1; LSM domain; \"\r"]
["O15118","NPC intracellular cholesterol transporter 1 OS=Homo sapiens OX=9606 GN=NPC1","NPC1",142.17,6.9383,2.9,3,3,3,1.074,1.181,0.937,0.93,1.005,0.896,0.887,0.196,"plasma membrane\r","GO:0044409 entry into host; GO:0044700 single organism signaling; GO:0043413 macromolecule glycosylation; GO:0010941 regulation of cell death; GO:0065008 regulation of biological quality; GO:0006066 alcohol metabolic process; GO:0006914 autophagy; GO:0044237 cellular metabolic process; GO:0007610 behavior; GO:0055098 response to low-density lipoprotein particle; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0048545 response to steroid hormone; GO:0032787 monocarboxylic acid metabolic process; GO:0009719 response to endogenous stimulus; GO:0055094 response to lipoprotein particle; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0008104 protein localization; GO:0044419 interspecies interaction between organisms; GO:0055088 lipid homeostasis; GO:0008206 bile acid metabolic process; GO:0046718 viral entry into host cell; GO:0044765 single-organism transport; GO:0006486 protein glycosylation; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0006869 lipid transport; GO:0072657 protein localization to membrane; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0044281 small molecule metabolic process; GO:0008202 steroid metabolic process; GO:0044763 single-organism cellular process; GO:0009100 glycoprotein metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0031323 regulation of cellular metabolic process; GO:2000189 positive regulation of cholesterol homeostasis; GO:0010506 regulation of autophagy; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0071396 cellular response to lipid; GO:0016241 regulation of macroautophagy; GO:0006810 transport; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0060548 negative regulation of cell death; GO:0043436 oxoacid metabolic process; GO:0044708 single-organism behavior; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:1901615 organic hydroxy compound metabolic process; GO:0051806 entry into cell of other organism involved in symbiotic interaction; GO:0044267 cellular protein metabolic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0032844 regulation of homeostatic process; GO:0016125 sterol metabolic process; GO:0042493 response to drug; GO:1902578 single-organism localization; GO:1901135 carbohydrate derivative metabolic process; GO:0044248 cellular catabolic process; GO:0006898 receptor-mediated endocytosis; GO:0034613 cellular protein localization; GO:0031579 membrane raft organization; GO:0030534 adult behavior; GO:0090150 establishment of protein localization to membrane; GO:0048878 chemical homeostasis; GO:2000188 regulation of cholesterol homeostasis; GO:0008203 cholesterol metabolic process; GO:0016192 vesicle-mediated transport; GO:0071407 cellular response to organic cyclic compound; GO:0071702 organic substance transport; GO:0010876 lipid localization; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0045184 establishment of protein localization; GO:0031330 negative regulation of cellular catabolic process; GO:0061024 membrane organization; GO:0043412 macromolecule modification; GO:0051179 localization; GO:0015850 organic hydroxy compound transport; GO:0030301 cholesterol transport; GO:0033344 cholesterol efflux; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0071383 cellular response to steroid hormone stimulus; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0032846 positive regulation of homeostatic process; GO:0046686 response to cadmium ion; GO:0010035 response to inorganic substance; GO:0007628 adult walking behavior; GO:0033036 macromolecule localization; GO:0070887 cellular response to chemical stimulus; GO:0006629 lipid metabolic process; GO:0009101 glycoprotein biosynthetic process; GO:0071402 cellular response to lipoprotein particle stimulus; GO:1901360 organic cyclic compound metabolic process; GO:0023052 signaling; GO:0010038 response to metal ion; GO:0030260 entry into host cell; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032870 cellular response to hormone stimulus; GO:0051828 entry into other organism involved in symbiotic interaction; GO:0019222 regulation of metabolic process; GO:0010507 negative regulation of autophagy; GO:0090659 walking behavior; GO:0006082 organic acid metabolic process; GO:0036211 protein modification process; GO:0016242 negative regulation of macroautophagy; GO:0015918 sterol transport; GO:0016043 cellular component organization; GO:0008344 adult locomotory behavior; GO:1902652 secondary alcohol metabolic process; GO:0071310 cellular response to organic substance; GO:0019058 viral life cycle; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0033993 response to lipid; GO:0016032 viral process; GO:0009895 negative regulation of catabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0070085 glycosylation; GO:0007041 lysosomal transport; GO:0071404 cellular response to low-density lipoprotein particle stimulus; GO:0044802 single-organism membrane organization; GO:0042632 cholesterol homeostasis; GO:0006897 endocytosis; GO:0051701 interaction with host; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0070727 cellular macromolecule localization; GO:0034645 cellular macromolecule biosynthetic process; GO:0071495 cellular response to endogenous stimulus; GO:0007034 vacuolar transport; GO:0055092 sterol homeostasis; GO:0019752 carboxylic acid metabolic process; GO:0007626 locomotory behavior; GO:0009725 response to hormone; GO:0009056 catabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0098857 membrane microdomain; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0005765 lysosomal membrane; GO:0070062 extracellular exosome; GO:0031902 late endosome membrane; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005764 lysosome; GO:0098589 membrane region; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0005768 endosome; GO:0045121 membrane raft; GO:0043227 membrane-bounded organelle; GO:0000323 lytic vacuole; GO:0010008 endosome membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0031226 intrinsic component of plasma membrane; GO:0005770 late endosome; GO:0098588 bounding membrane of organelle; GO:0005635 nuclear envelope; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0044440 endosomal part; GO:0012505 endomembrane system; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0031975 envelope; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0038023 signaling receptor activity; GO:0015485 cholesterol binding; GO:0032934 sterol binding; GO:0005319 lipid transporter activity; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0004888 transmembrane signaling receptor activity; GO:0004871 signal transducer activity; GO:0001618 virus receptor activity; GO:0005496 steroid binding; GO:0097159 organic cyclic compound binding; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0043178 alcohol binding; GO:0005488 binding; GO:0008289 lipid binding; GO:0015248 sterol transporter activity; GO:0036094 small molecule binding; GO:0005215 transporter activity; GO:0099600 transmembrane receptor activity; ","K12385","NPC1; Niemann-Pick C1 protein","hsa04142 Lysosome - Homo sapiens (human); hsa04979 Cholesterol metabolism - Homo sapiens (human); ","IPR032190; IPR000731; ","\"Niemann-Pick C1, N-terminal; Sterol-sensing domain; \"\r"]
["O15126","Secretory carrier-associated membrane protein 1 OS=Homo sapiens OX=9606 GN=SCAMP1","SCAMP1",37.92,5.3399,5.6,2,3,2,1.096,1.06,1.003,0.949,0.944,0.964,0.904,0.0199,"plasma membrane\r","GO:0045321 leukocyte activation; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0048193 Golgi vesicle transport; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0036230 granulocyte activation; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0009987 cellular process; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0002274 myeloid leukocyte activation; GO:0002443 leukocyte mediated immunity; GO:0016192 vesicle-mediated transport; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0071702 organic substance transport; GO:0002376 immune system process; GO:0043312 neutrophil degranulation; GO:0002263 cell activation involved in immune response; GO:0002444 myeloid leukocyte mediated immunity; GO:0045184 establishment of protein localization; GO:0002366 leukocyte activation involved in immune response; GO:0006810 transport; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0032940 secretion by cell; GO:0001775 cell activation; GO:0043299 leukocyte degranulation; GO:0006892 post-Golgi vesicle-mediated transport; GO:0006955 immune response; GO:0051179 localization; GO:0006887 exocytosis; ","GO:0030658 transport vesicle membrane; GO:0016020 membrane; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0042588 zymogen granule; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0055038 recycling endosome membrane; GO:0099501 exocytic vesicle membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0055037 recycling endosome; GO:0070382 exocytic vesicle; GO:0030136 clathrin-coated vesicle; GO:0008021 synaptic vesicle; GO:0044425 membrane part; GO:0098793 presynapse; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0098805 whole membrane; GO:0098791 Golgi subcompartment; GO:0044431 Golgi apparatus part; GO:0042589 zymogen granule membrane; GO:0005768 endosome; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0035579 specific granule membrane; GO:0097458 neuron part; GO:0044456 synapse part; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0010008 endosome membrane; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0030672 synaptic vesicle membrane; GO:0030135 coated vesicle; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0045202 synapse; GO:0030659 cytoplasmic vesicle membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0030667 secretory granule membrane; GO:0042581 specific granule; GO:0005802 trans-Golgi network; GO:0005794 Golgi apparatus; GO:0030133 transport vesicle; GO:0031984 organelle subcompartment; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ","K19995"]
["O15127","Secretory carrier-associated membrane protein 2 OS=Homo sapiens OX=9606 GN=SCAMP2","SCAMP2",36.648,35.376,13.7,3,3,3,0.906,0.962,1.068,1.145,0.898,1.029,1.046,0.643,"plasma membrane\r","GO:0045184 establishment of protein localization; GO:0006810 transport; GO:0016192 vesicle-mediated transport; GO:0048193 Golgi vesicle transport; GO:0071702 organic substance transport; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0051179 localization; GO:0006892 post-Golgi vesicle-mediated transport; GO:0015031 protein transport; GO:0051234 establishment of localization; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0031224 intrinsic component of membrane; GO:0032588 trans-Golgi network membrane; GO:0055038 recycling endosome membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0055037 recycling endosome; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0098791 Golgi subcompartment; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0010008 endosome membrane; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005802 trans-Golgi network; GO:0030133 transport vesicle; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0031984 organelle subcompartment; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ","K19995"]
["O15143","Actin-related protein 2/3 complex subunit 1B OS=Homo sapiens OX=9606 GN=ARPC1B","ARPC1B",40.949,74.09,33.6,10,13,9,1.009,0.971,0.966,1.007,1.016,1.009,1.029,0.107,"cytoplasm\r","GO:0044700 single organism signaling; GO:0030833 regulation of actin filament polymerization; GO:0034314 Arp2/3 complex-mediated actin nucleation; GO:0065008 regulation of biological quality; GO:0032273 positive regulation of protein polymerization; GO:0007166 cell surface receptor signaling pathway; GO:0043627 response to estrogen; GO:0038094 Fc-gamma receptor signaling pathway; GO:0044699 single-organism process; GO:0030832 regulation of actin filament length; GO:0051234 establishment of localization; GO:0006909 phagocytosis; GO:0051130 positive regulation of cellular component organization; GO:0007165 signal transduction; GO:0030036 actin cytoskeleton organization; GO:0007154 cell communication; GO:0045010 actin nucleation; GO:0032535 regulation of cellular component size; GO:0032271 regulation of protein polymerization; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0031334 positive regulation of protein complex assembly; GO:0051493 regulation of cytoskeleton organization; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0044765 single-organism transport; GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis; GO:0051716 cellular response to stimulus; GO:0014070 response to organic cyclic compound; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0048522 positive regulation of cellular process; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0050776 regulation of immune response; GO:0006810 transport; GO:1902589 single-organism organelle organization; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0043254 regulation of protein complex assembly; GO:0010638 positive regulation of organelle organization; GO:0048583 regulation of response to stimulus; GO:0002682 regulation of immune system process; GO:1902905 positive regulation of supramolecular fiber organization; GO:0002431 Fc receptor mediated stimulatory signaling pathway; GO:0097435 supramolecular fiber organization; GO:1902903 regulation of supramolecular fiber organization; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0002252 immune effector process; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0032956 regulation of actin cytoskeleton organization; GO:1901700 response to oxygen-containing compound; GO:0007015 actin filament organization; GO:0044087 regulation of cellular component biogenesis; GO:0032355 response to estradiol; GO:0050896 response to stimulus; GO:0033993 response to lipid; GO:1902578 single-organism localization; GO:0048013 ephrin receptor signaling pathway; GO:0002757 immune response-activating signal transduction; GO:0038093 Fc receptor signaling pathway; GO:0007010 cytoskeleton organization; GO:0050778 positive regulation of immune response; GO:0009987 cellular process; GO:0002253 activation of immune response; GO:0051495 positive regulation of cytoskeleton organization; GO:0016192 vesicle-mediated transport; GO:0033043 regulation of organelle organization; GO:0002376 immune system process; GO:0032970 regulation of actin filament-based process; GO:0010033 response to organic substance; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0030838 positive regulation of actin filament polymerization; GO:0008064 regulation of actin polymerization or depolymerization; GO:0006996 organelle organization; GO:0002684 positive regulation of immune system process; GO:0030029 actin filament-based process; GO:0090066 regulation of anatomical structure size; GO:0006928 movement of cell or subcellular component; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis; GO:0048584 positive regulation of response to stimulus; GO:0044089 positive regulation of cellular component biogenesis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0044421 extracellular region part; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0005885 Arp2/3 protein complex; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0036284 tubulobulbar complex; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0005829 cytosol; GO:0015629 actin cytoskeleton; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0008092 cytoskeletal protein binding; GO:0005200 structural constituent of cytoskeleton; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0003779 actin binding; GO:0005515 protein binding; GO:0005198 structural molecule activity; GO:0032403 protein complex binding; ","K05757","ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B","hsa05100 Bacterial invasion of epithelial cells - Homo sapiens (human); hsa05132 Salmonella infection - Homo sapiens (human); hsa04666 Fc gamma R-mediated phagocytosis - Homo sapiens (human); hsa04144 Endocytosis - Homo sapiens (human); hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human); hsa05131 Shigellosis - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); ","IPR017986; IPR015943; ","WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain; \r"]
["O15144","Actin-related protein 2/3 complex subunit 2 OS=Homo sapiens OX=9606 GN=ARPC2","ARPC2",34.333,45.275,35,12,30,12,0.953,0.932,0.953,1.025,1.096,1.003,1.101,0.0262,"cytoplasm\r","GO:0044700 single organism signaling; GO:0030833 regulation of actin filament polymerization; GO:0034314 Arp2/3 complex-mediated actin nucleation; GO:0065008 regulation of biological quality; GO:0032273 positive regulation of protein polymerization; GO:0060491 regulation of cell projection assembly; GO:0007166 cell surface receptor signaling pathway; GO:0038094 Fc-gamma receptor signaling pathway; GO:0044699 single-organism process; GO:0030832 regulation of actin filament length; GO:0051234 establishment of localization; GO:0006909 phagocytosis; GO:0051130 positive regulation of cellular component organization; GO:0007165 signal transduction; GO:0030036 actin cytoskeleton organization; GO:0007154 cell communication; GO:0045010 actin nucleation; GO:0032535 regulation of cellular component size; GO:0032271 regulation of protein polymerization; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0031334 positive regulation of protein complex assembly; GO:0051493 regulation of cytoskeleton organization; GO:0010720 positive regulation of cell development; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0044765 single-organism transport; GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis; GO:0051716 cellular response to stimulus; GO:0031346 positive regulation of cell projection organization; GO:1900026 positive regulation of substrate adhesion-dependent cell spreading; GO:0010591 regulation of lamellipodium assembly; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0048522 positive regulation of cellular process; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0010811 positive regulation of cell-substrate adhesion; GO:0050776 regulation of immune response; GO:0006810 transport; GO:1902745 positive regulation of lamellipodium organization; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0043254 regulation of protein complex assembly; GO:0010638 positive regulation of organelle organization; GO:0048583 regulation of response to stimulus; GO:0002682 regulation of immune system process; GO:1902905 positive regulation of supramolecular fiber organization; GO:0002431 Fc receptor mediated stimulatory signaling pathway; GO:0051094 positive regulation of developmental process; GO:0097435 supramolecular fiber organization; GO:1902903 regulation of supramolecular fiber organization; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0002252 immune effector process; GO:0032956 regulation of actin cytoskeleton organization; GO:0007015 actin filament organization; GO:0010770 positive regulation of cell morphogenesis involved in differentiation; GO:0031344 regulation of cell projection organization; GO:0044087 regulation of cellular component biogenesis; GO:0050896 response to stimulus; GO:0045597 positive regulation of cell differentiation; GO:1902578 single-organism localization; GO:1902743 regulation of lamellipodium organization; GO:0048013 ephrin receptor signaling pathway; GO:1900024 regulation of substrate adhesion-dependent cell spreading; GO:0002757 immune response-activating signal transduction; GO:0010592 positive regulation of lamellipodium assembly; GO:0038093 Fc receptor signaling pathway; GO:0007010 cytoskeleton organization; GO:0050778 positive regulation of immune response; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0002253 activation of immune response; GO:0051495 positive regulation of cytoskeleton organization; GO:0045785 positive regulation of cell adhesion; GO:0016192 vesicle-mediated transport; GO:0060284 regulation of cell development; GO:0033043 regulation of organelle organization; GO:0002376 immune system process; GO:0032970 regulation of actin filament-based process; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0030838 positive regulation of actin filament polymerization; GO:0030155 regulation of cell adhesion; GO:0008064 regulation of actin polymerization or depolymerization; GO:0006996 organelle organization; GO:0002684 positive regulation of immune system process; GO:0061024 membrane organization; GO:0030029 actin filament-based process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0006928 movement of cell or subcellular component; GO:0090066 regulation of anatomical structure size; GO:0051128 regulation of cellular component organization; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:0051179 localization; GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis; GO:0048584 positive regulation of response to stimulus; GO:0010810 regulation of cell-substrate adhesion; GO:0050793 regulation of developmental process; GO:0022604 regulation of cell morphogenesis; GO:0044089 positive regulation of cellular component biogenesis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0036195 muscle cell projection membrane; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005856 cytoskeleton; GO:0005885 Arp2/3 protein complex; GO:0005925 focal adhesion; GO:0098590 plasma membrane region; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0005768 endosome; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0005924 cell-substrate adherens junction; GO:0097708 intracellular vesicle; GO:0031252 cell leading edge; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0012505 endomembrane system; GO:0044463 cell projection part; GO:0005829 cytosol; GO:0015629 actin cytoskeleton; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0045202 synapse; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0031253 cell projection membrane; GO:0043234 protein complex; GO:0036194 muscle cell projection; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0003779 actin binding; GO:0005515 protein binding; GO:0008092 cytoskeletal protein binding; GO:0005200 structural constituent of cytoskeleton; GO:0005198 structural molecule activity; GO:0005488 binding; ","K05758","ARPC2; actin related protein 2/3 complex, subunit 2","hsa05100 Bacterial invasion of epithelial cells - Homo sapiens (human); hsa05132 Salmonella infection - Homo sapiens (human); hsa04666 Fc gamma R-mediated phagocytosis - Homo sapiens (human); hsa04144 Endocytosis - Homo sapiens (human); hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human); hsa05131 Shigellosis - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); "]
["O15145","Actin-related protein 2/3 complex subunit 3 OS=Homo sapiens OX=9606 GN=ARPC3","ARPC3",20.546,25.829,25.3,5,12,5,0.953,0.948,0.998,1.094,1.019,1.033,1.085,0.04,"cytoplasm\r","GO:0044700 single organism signaling; GO:0030833 regulation of actin filament polymerization; GO:0034314 Arp2/3 complex-mediated actin nucleation; GO:0065008 regulation of biological quality; GO:0032273 positive regulation of protein polymerization; GO:0007166 cell surface receptor signaling pathway; GO:0038094 Fc-gamma receptor signaling pathway; GO:0044699 single-organism process; GO:0071363 cellular response to growth factor stimulus; GO:0030832 regulation of actin filament length; GO:0051234 establishment of localization; GO:0006909 phagocytosis; GO:0051130 positive regulation of cellular component organization; GO:0007165 signal transduction; GO:0030036 actin cytoskeleton organization; GO:0007154 cell communication; GO:0045010 actin nucleation; GO:0032535 regulation of cellular component size; GO:0009719 response to endogenous stimulus; GO:0032271 regulation of protein polymerization; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0070848 response to growth factor; GO:0031334 positive regulation of protein complex assembly; GO:0051493 regulation of cytoskeleton organization; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0070887 cellular response to chemical stimulus; GO:0044765 single-organism transport; GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis; GO:0051716 cellular response to stimulus; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0048522 positive regulation of cellular process; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0050776 regulation of immune response; GO:0006810 transport; GO:1902589 single-organism organelle organization; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0043254 regulation of protein complex assembly; GO:0010638 positive regulation of organelle organization; GO:0048583 regulation of response to stimulus; GO:0002682 regulation of immune system process; GO:1902905 positive regulation of supramolecular fiber organization; GO:0002431 Fc receptor mediated stimulatory signaling pathway; GO:0097435 supramolecular fiber organization; GO:1902903 regulation of supramolecular fiber organization; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0002252 immune effector process; GO:0032956 regulation of actin cytoskeleton organization; GO:0071310 cellular response to organic substance; GO:0007015 actin filament organization; GO:0044087 regulation of cellular component biogenesis; GO:0050896 response to stimulus; GO:1902578 single-organism localization; GO:0048013 ephrin receptor signaling pathway; GO:0002757 immune response-activating signal transduction; GO:0038093 Fc receptor signaling pathway; GO:0007010 cytoskeleton organization; GO:0050778 positive regulation of immune response; GO:0009987 cellular process; GO:0002253 activation of immune response; GO:1990089 response to nerve growth factor; GO:0051495 positive regulation of cytoskeleton organization; GO:1990090 cellular response to nerve growth factor stimulus; GO:0016192 vesicle-mediated transport; GO:0033043 regulation of organelle organization; GO:0002376 immune system process; GO:0032970 regulation of actin filament-based process; GO:0010033 response to organic substance; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0030838 positive regulation of actin filament polymerization; GO:0008064 regulation of actin polymerization or depolymerization; GO:0006996 organelle organization; GO:0071495 cellular response to endogenous stimulus; GO:0002684 positive regulation of immune system process; GO:0030029 actin filament-based process; GO:0061024 membrane organization; GO:0006928 movement of cell or subcellular component; GO:0090066 regulation of anatomical structure size; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis; GO:0048584 positive regulation of response to stimulus; GO:0044089 positive regulation of cellular component biogenesis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0030426 growth cone; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005856 cytoskeleton; GO:0005885 Arp2/3 protein complex; GO:0005925 focal adhesion; GO:0044464 cell part; GO:0005622 intracellular; GO:0030027 lamellipodium; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0005884 actin filament; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0005924 cell-substrate adherens junction; GO:0031941 filamentous actin; GO:0031252 cell leading edge; GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0030427 site of polarized growth; GO:0044463 cell projection part; GO:0005829 cytosol; GO:0015629 actin cytoskeleton; GO:0005576 extracellular region; GO:0099081 supramolecular polymer; GO:0043226 organelle; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0003779 actin binding; GO:0005515 protein binding; GO:0008092 cytoskeletal protein binding; GO:0005200 structural constituent of cytoskeleton; GO:0005198 structural molecule activity; GO:0005488 binding; ","K05756","ARPC3; actin related protein 2/3 complex, subunit 3","hsa05100 Bacterial invasion of epithelial cells - Homo sapiens (human); hsa05132 Salmonella infection - Homo sapiens (human); hsa04666 Fc gamma R-mediated phagocytosis - Homo sapiens (human); hsa04144 Endocytosis - Homo sapiens (human); hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human); hsa05131 Shigellosis - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); "]
["O15155","BET1 homolog OS=Homo sapiens OX=9606 GN=BET1","BET1",13.289,3.8581,9.3,1,1,1,1.034,0.971,1.052,1.055,0.985,0.915,0.967,0.504,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0051640 organelle localization; GO:0090174 organelle membrane fusion; GO:0016043 cellular component organization; GO:0006901 vesicle coating; GO:0046907 intracellular transport; GO:0048207 vesicle targeting, rough ER to cis-Golgi; GO:0048208 COPII vesicle coating; GO:0044699 single-organism process; GO:0048193 Golgi vesicle transport; GO:0048280 vesicle fusion with Golgi apparatus; GO:0006903 vesicle targeting; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0051649 establishment of localization in cell; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0051648 vesicle localization; GO:0048199 vesicle targeting, to, from or within Golgi; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0044801 single-organism membrane fusion; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0051650 establishment of vesicle localization; GO:0071822 protein complex subunit organization; GO:0090114 COPII-coated vesicle budding; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0044802 single-organism membrane organization; GO:0061025 membrane fusion; GO:0016050 vesicle organization; GO:0071702 organic substance transport; GO:0048284 organelle fusion; GO:0051656 establishment of organelle localization; GO:0043933 macromolecular complex subunit organization; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:1902589 single-organism organelle organization; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0006900 membrane budding; GO:0006906 vesicle fusion; GO:0051179 localization; GO:0070271 protein complex biogenesis; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0005801 cis-Golgi network; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098791 Golgi subcompartment; GO:0044431 Golgi apparatus part; GO:0043227 membrane-bounded organelle; GO:0031201 SNARE complex; GO:0005789 endoplasmic reticulum membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0005795 Golgi stack; GO:0012505 endomembrane system; GO:0016021 integral component of membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044432 endoplasmic reticulum part; GO:0005793 endoplasmic reticulum-Golgi intermediate compartment; GO:0043234 protein complex; GO:0005794 Golgi apparatus; GO:0030133 transport vesicle; GO:0031985 Golgi cisterna; GO:0031984 organelle subcompartment; GO:0044444 cytoplasmic part; ","GO:0000149 SNARE binding; GO:0005515 protein binding; GO:0019905 syntaxin binding; GO:0005488 binding; ","K08504","BET1; blocked early in transport 1","hsa04130 SNARE interactions in vesicular transport - Homo sapiens (human); ","IPR000727; ","Target SNARE coiled-coil homology domain; \r"]
["O15173","Membrane-associated progesterone receptor component 2 OS=Homo sapiens OX=9606 GN=PGRMC2","PGRMC2",23.818,48.947,25.6,5,10,4,1.095,1.099,1.087,0.92,0.914,0.935,0.844,2.12E-5,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0051716 cellular response to stimulus; GO:0014070 response to organic cyclic compound; GO:0071310 cellular response to organic substance; GO:0044699 single-organism process; GO:0071407 cellular response to organic cyclic compound; GO:0010033 response to organic substance; GO:0050896 response to stimulus; GO:0023052 signaling; GO:0071383 cellular response to steroid hormone stimulus; GO:0009755 hormone-mediated signaling pathway; GO:0071396 cellular response to lipid; GO:0033993 response to lipid; GO:0007165 signal transduction; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0007154 cell communication; GO:0032870 cellular response to hormone stimulus; GO:0071495 cellular response to endogenous stimulus; GO:0048545 response to steroid hormone; GO:0009719 response to endogenous stimulus; GO:0009725 response to hormone; GO:0043401 steroid hormone mediated signaling pathway; GO:0009987 cellular process; GO:0070887 cellular response to chemical stimulus; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005635 nuclear envelope; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0031975 envelope; GO:0043227 membrane-bounded organelle; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003707 steroid hormone receptor activity; GO:0038023 signaling receptor activity; GO:0020037 heme binding; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0005488 binding; GO:0008289 lipid binding; GO:0005515 protein binding; GO:0046906 tetrapyrrole binding; GO:0004871 signal transducer activity; GO:0005496 steroid binding; ","K17278",null,null,"IPR001199; ","Cytochrome b5-like heme/steroid binding domain; \r"]
["O15212","Prefoldin subunit 6 OS=Homo sapiens OX=9606 GN=PFDN6","PFDN6",14.582,20.196,20.2,2,5,2,1.011,1.01,0.947,1.004,1.016,1.02,1.024,0.332,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0006457 protein folding; GO:0016043 cellular component organization; GO:0034622 cellular macromolecular complex assembly; GO:0071822 protein complex subunit organization; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0051131 chaperone-mediated protein complex assembly; GO:0070271 protein complex biogenesis; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0071840 cellular component organization or biogenesis; GO:0043623 cellular protein complex assembly; GO:0043933 macromolecular complex subunit organization; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0016272 prefoldin complex; GO:0044424 intracellular part; GO:0043234 protein complex; GO:0005623 cell; ","GO:0005515 protein binding; GO:0051082 unfolded protein binding; GO:0051087 chaperone binding; GO:0005488 binding; ","K04798"]
["O15217","Glutathione S-transferase A4 OS=Homo sapiens OX=9606 GN=GSTA4","GSTA4",25.704,18.427,16.7,3,5,3,0.852,0.855,0.957,1.105,1.11,1.111,1.248,0.028,"cytoplasm\r","GO:0006790 sulfur compound metabolic process; GO:0071466 cellular response to xenobiotic stimulus; GO:0051716 cellular response to stimulus; GO:0006518 peptide metabolic process; GO:0044711 single-organism biosynthetic process; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0006807 nitrogen compound metabolic process; GO:0009058 biosynthetic process; GO:0043603 cellular amide metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:1901576 organic substance biosynthetic process; GO:0044237 cellular metabolic process; GO:0044272 sulfur compound biosynthetic process; GO:0044249 cellular biosynthetic process; GO:1901687 glutathione derivative biosynthetic process; GO:0071704 organic substance metabolic process; GO:1901685 glutathione derivative metabolic process; GO:0008152 metabolic process; GO:0042221 response to chemical; GO:0009410 response to xenobiotic stimulus; GO:0006805 xenobiotic metabolic process; GO:0006575 cellular modified amino acid metabolic process; GO:0044710 single-organism metabolic process; GO:0006749 glutathione metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009987 cellular process; GO:0070887 cellular response to chemical stimulus; GO:1901564 organonitrogen compound metabolic process; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0044444 cytoplasmic part; ","GO:0004364 glutathione transferase activity; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0046983 protein dimerization activity; GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups; GO:0005515 protein binding; GO:0016740 transferase activity; ","K00799","GST; glutathione S-transferase [EC:2.5.1.18]","hsa01524 Platinum drug resistance - Homo sapiens (human); hsa00480 Glutathione metabolism - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa05204 Chemical carcinogenesis - Homo sapiens (human); hsa00980 Metabolism of xenobiotics by cytochrome P450 - Homo sapiens (human); hsa05225 Hepatocellular carcinoma - Homo sapiens (human); hsa00983 Drug metabolism - other enzymes - Homo sapiens (human); hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human); hsa00982 Drug metabolism - cytochrome P450 - Homo sapiens (human); hsa05215 Prostate cancer - Homo sapiens (human); ","IPR004046; IPR010987; IPR012336; IPR004045; ","\"Glutathione S-transferase, C-terminal; Glutathione S-transferase, C-terminal-like; Thioredoxin-like fold; Glutathione S-transferase, N-terminal; \"\r"]
["O15230","Laminin subunit alpha-5 OS=Homo sapiens OX=9606 GN=LAMA5","LAMA5",399.73,30.017,3.5,10,10,10,1.014,1.065,1.16,0.879,0.904,0.992,0.857,0.0451,"extracellular\r","GO:0044700 single organism signaling; GO:0072028 nephron morphogenesis; GO:0044085 cellular component biogenesis; GO:0001738 morphogenesis of a polarized epithelium; GO:0048732 gland development; GO:0061333 renal tubule morphogenesis; GO:0007166 cell surface receptor signaling pathway; GO:0072080 nephron tubule development; GO:0030323 respiratory tube development; GO:0032989 cellular component morphogenesis; GO:0060271 cilium assembly; GO:0090002 establishment of protein localization to plasma membrane; GO:0044782 cilium organization; GO:0048754 branching morphogenesis of an epithelial tube; GO:0022610 biological adhesion; GO:0001755 neural crest cell migration; GO:0001525 angiogenesis; GO:0034446 substrate adhesion-dependent cell spreading; GO:0032879 regulation of localization; GO:0007160 cell-matrix adhesion; GO:0008544 epidermis development; GO:0034332 adherens junction organization; GO:0007155 cell adhesion; GO:0009790 embryo development; GO:0008104 protein localization; GO:0048598 embryonic morphogenesis; GO:0060445 branching involved in salivary gland morphogenesis; GO:0051716 cellular response to stimulus; GO:0043588 skin development; GO:0072657 protein localization to membrane; GO:0001763 morphogenesis of a branching structure; GO:0035239 tube morphogenesis; GO:0044763 single-organism cellular process; GO:0048870 cell motility; GO:0007009 plasma membrane organization; GO:0032501 multicellular organismal process; GO:0048041 focal adhesion assembly; GO:0000902 cell morphogenesis; GO:0098773 skin epidermis development; GO:0048513 animal organ development; GO:0098602 single organism cell adhesion; GO:0009887 animal organ morphogenesis; GO:0001942 hair follicle development; GO:0030855 epithelial cell differentiation; GO:0072359 circulatory system development; GO:0050794 regulation of cellular process; GO:0002009 morphogenesis of an epithelium; GO:0044707 single-multicellular organism process; GO:0042127 regulation of cell proliferation; GO:0042303 molting cycle; GO:0051239 regulation of multicellular organismal process; GO:1990778 protein localization to cell periphery; GO:0009653 anatomical structure morphogenesis; GO:1902578 single-organism localization; GO:2000145 regulation of cell motility; GO:0060541 respiratory system development; GO:0043062 extracellular structure organization; GO:0061061 muscle structure development; GO:1902580 single-organism cellular localization; GO:0016331 morphogenesis of embryonic epithelium; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0034613 cellular protein localization; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0090150 establishment of protein localization to membrane; GO:0072009 nephron epithelium development; GO:0001822 kidney development; GO:0060562 epithelial tube morphogenesis; GO:0051270 regulation of cellular component movement; GO:0060485 mesenchyme development; GO:0048731 system development; GO:0030334 regulation of cell migration; GO:0008283 cell proliferation; GO:0072358 cardiovascular system development; GO:0022405 hair cycle process; GO:0061326 renal tubule development; GO:0042633 hair cycle; GO:0030155 regulation of cell adhesion; GO:0003158 endothelium development; GO:0030031 cell projection assembly; GO:0045184 establishment of protein localization; GO:0014032 neural crest cell development; GO:0072659 protein localization to plasma membrane; GO:0061138 morphogenesis of a branching epithelium; GO:0014033 neural crest cell differentiation; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0048863 stem cell differentiation; GO:0006928 movement of cell or subcellular component; GO:0072073 kidney epithelium development; GO:0007435 salivary gland morphogenesis; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0001657 ureteric bud development; GO:0010256 endomembrane system organization; GO:0051674 localization of cell; GO:0001568 blood vessel development; GO:0048869 cellular developmental process; GO:0045216 cell-cell junction organization; GO:0044699 single-organism process; GO:0060675 ureteric bud morphogenesis; GO:0045446 endothelial cell differentiation; GO:0051234 establishment of localization; GO:0001823 mesonephros development; GO:0007165 signal transduction; GO:0048729 tissue morphogenesis; GO:0022404 molting cycle process; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0042475 odontogenesis of dentin-containing tooth; GO:0007045 cell-substrate adherens junction assembly; GO:0048514 blood vessel morphogenesis; GO:0030198 extracellular matrix organization; GO:0033036 macromolecule localization; GO:0030324 lung development; GO:0032502 developmental process; GO:0007044 cell-substrate junction assembly; GO:0060429 epithelium development; GO:0035295 tube development; GO:0009888 tissue development; GO:0001944 vasculature development; GO:0007229 integrin-mediated signaling pathway; GO:0023052 signaling; GO:0072171 mesonephric tubule morphogenesis; GO:0042476 odontogenesis; GO:1902589 single-organism organelle organization; GO:0001655 urogenital system development; GO:0050789 regulation of biological process; GO:0007517 muscle organ development; GO:0030030 cell projection organization; GO:0001667 ameboidal-type cell migration; GO:0034333 adherens junction assembly; GO:0040011 locomotion; GO:0072163 mesonephric epithelium development; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0034329 cell junction assembly; GO:0016043 cellular component organization; GO:0016477 cell migration; GO:0072078 nephron tubule morphogenesis; GO:0014031 mesenchymal cell development; GO:0001658 branching involved in ureteric bud morphogenesis; GO:0007431 salivary gland development; GO:0072001 renal system development; GO:0048864 stem cell development; GO:0050896 response to stimulus; GO:0008037 cell recognition; GO:0072088 nephron epithelium morphogenesis; GO:0048468 cell development; GO:0000904 cell morphogenesis involved in differentiation; GO:0030154 cell differentiation; GO:0070925 organelle assembly; GO:0072006 nephron development; GO:0060993 kidney morphogenesis; GO:0009987 cellular process; GO:0035272 exocrine system development; GO:0072164 mesonephric tubule development; GO:0044802 single-organism membrane organization; GO:0051641 cellular localization; GO:0070727 cellular macromolecule localization; GO:0045995 regulation of embryonic development; GO:0034330 cell junction organization; GO:0031589 cell-substrate adhesion; GO:0044767 single-organism developmental process; GO:0040012 regulation of locomotion; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:0048762 mesenchymal cell differentiation; GO:0022612 gland morphogenesis; ","GO:0043229 intracellular organelle; GO:0043260 laminin-11 complex; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0044420 extracellular matrix component; GO:0043083 synaptic cleft; GO:0045202 synapse; GO:0043256 laminin complex; GO:0005604 basement membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0031012 extracellular matrix; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005605 basal lamina; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0005578 proteinaceous extracellular matrix; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0043259 laminin-10 complex; GO:0005610 laminin-5 complex; GO:0043230 extracellular organelle; GO:0044456 synapse part; ","GO:0050839 cell adhesion molecule binding; GO:0005102 receptor binding; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0005515 protein binding; GO:0005178 integrin binding; GO:0005198 structural molecule activity; GO:0032403 protein complex binding; ","K06240","LAMA3_5; laminin, alpha 3/5","hsa05200 Pathways in cancer - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa05146 Amoebiasis - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa05222 Small cell lung cancer - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa04512 ECM-receptor interaction - Homo sapiens (human); hsa05145 Toxoplasmosis - Homo sapiens (human); ","IPR001368; IPR000034; IPR000742; IPR008211; IPR001791; IPR013320; IPR009254; IPR002049; IPR010307; ","\"TNFR/NGFR cysteine-rich region; Laminin IV; EGF-like domain; Laminin, N-terminal; Laminin G domain; Concanavalin A-like lectin/glucanase domain; Laminin alpha, domain I; Laminin EGF domain; Laminin domain II; \"\r"]
["O15231","Zinc finger protein 185 OS=Homo sapiens OX=9606 GN=ZNF185","ZNF185",73.525,109.21,26.1,16,22,16,0.92,0.91,0.928,1.082,1.088,1.011,1.153,0.00424,"cyto_nucl\r",null,"GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0070161 anchoring junction; GO:0044424 intracellular part; GO:0005623 cell; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0005856 cytoskeleton; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:0030055 cell-substrate junction; GO:0005924 cell-substrate adherens junction; ","GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0008270 zinc ion binding; GO:0046914 transition metal ion binding; GO:0005488 binding; GO:0043167 ion binding; ",{"$nulls":3},"IPR001781; ","\"Zinc finger, LIM-type; \"\r"]
["O15247","Chloride intracellular channel protein 2 OS=Homo sapiens OX=9606 GN=CLIC2","CLIC2",28.356,51.283,27.5,4,5,4,0.941,1.07,0.965,0.946,0.949,0.999,0.972,0.569,"cytoplasm\r","GO:0098661 inorganic anion transmembrane transport; GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling; GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:1903170 negative regulation of calcium ion transmembrane transport; GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity; GO:0010469 regulation of receptor activity; GO:0051234 establishment of localization; GO:0090281 negative regulation of calcium ion import; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0055117 regulation of cardiac muscle contraction; GO:1901019 regulation of calcium ion transmembrane transporter activity; GO:0032879 regulation of localization; GO:0032846 positive regulation of homeostatic process; GO:0044093 positive regulation of molecular function; GO:0044057 regulation of system process; GO:2001258 negative regulation of cation channel activity; GO:0098869 cellular oxidant detoxification; GO:0032413 negative regulation of ion transmembrane transporter activity; GO:0051099 positive regulation of binding; GO:1901020 negative regulation of calcium ion transmembrane transporter activity; GO:0051051 negative regulation of transport; GO:0051716 cellular response to stimulus; GO:0051284 positive regulation of sequestering of calcium ion; GO:0051279 regulation of release of sequestered calcium ion into cytosol; GO:0009636 response to toxic substance; GO:0051098 regulation of binding; GO:0043269 regulation of ion transport; GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; GO:0048522 positive regulation of cellular process; GO:0022898 regulation of transmembrane transporter activity; GO:0019932 second-messenger-mediated signaling; GO:0090257 regulation of muscle system process; GO:0023052 signaling; GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; GO:0006942 regulation of striated muscle contraction; GO:0034762 regulation of transmembrane transport; GO:0006810 transport; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:1902532 negative regulation of intracellular signal transduction; GO:0048583 regulation of response to stimulus; GO:2001257 regulation of cation channel activity; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0032412 regulation of ion transmembrane transporter activity; GO:0098754 detoxification; GO:0015698 inorganic anion transport; GO:0050794 regulation of cellular process; GO:0034220 ion transmembrane transport; GO:2000021 regulation of ion homeostasis; GO:1903522 regulation of blood circulation; GO:0006821 chloride transport; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0008016 regulation of heart contraction; GO:0032844 regulation of homeostatic process; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:0098656 anion transmembrane transport; GO:0060341 regulation of cellular localization; GO:1902476 chloride transmembrane transport; GO:0023057 negative regulation of signaling; GO:1990748 cellular detoxification; GO:0010648 negative regulation of cell communication; GO:0019722 calcium-mediated signaling; GO:0032410 negative regulation of transporter activity; GO:1903169 regulation of calcium ion transmembrane transport; GO:0010959 regulation of metal ion transport; GO:0050848 regulation of calcium-mediated signaling; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:0032409 regulation of transporter activity; GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity; GO:1904062 regulation of cation transmembrane transport; GO:0034763 negative regulation of transmembrane transport; GO:0043271 negative regulation of ion transport; GO:1902531 regulation of intracellular signal transduction; GO:0051282 regulation of sequestering of calcium ion; GO:0035556 intracellular signal transduction; GO:0098660 inorganic ion transmembrane transport; GO:0051926 negative regulation of calcium ion transport; GO:0051049 regulation of transport; GO:0090279 regulation of calcium ion import; GO:0006937 regulation of muscle contraction; GO:0010523 negative regulation of calcium ion transport into cytosol; GO:0051924 regulation of calcium ion transport; GO:2000272 negative regulation of receptor activity; GO:0048585 negative regulation of response to stimulus; GO:0032845 negative regulation of homeostatic process; GO:0048518 positive regulation of biological process; GO:0034766 negative regulation of ion transmembrane transport; GO:0050849 negative regulation of calcium-mediated signaling; GO:0006820 anion transport; GO:1904063 negative regulation of cation transmembrane transport; GO:0055085 transmembrane transport; GO:0034765 regulation of ion transmembrane transport; GO:0006811 ion transport; GO:0051280 negative regulation of release of sequestered calcium ion into cytosol; GO:0010522 regulation of calcium ion transport into cytosol; GO:0051179 localization; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:1902495 transmembrane transporter complex; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0034707 chloride channel complex; GO:0034702 ion channel complex; GO:1990351 transporter complex; GO:0043227 membrane-bounded organelle; ","GO:0015075 ion transmembrane transporter activity; GO:0004602 glutathione peroxidase activity; GO:0022803 passive transmembrane transporter activity; GO:0005253 anion channel activity; GO:0016209 antioxidant activity; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0005254 chloride channel activity; GO:0015267 channel activity; GO:0015103 inorganic anion transmembrane transporter activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0016491 oxidoreductase activity; GO:0015108 chloride transmembrane transporter activity; GO:0005244 voltage-gated ion channel activity; GO:0022838 substrate-specific channel activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0022836 gated channel activity; GO:0005216 ion channel activity; GO:0004601 peroxidase activity; GO:0022832 voltage-gated channel activity; GO:0022857 transmembrane transporter activity; GO:0005215 transporter activity; GO:0008509 anion transmembrane transporter activity; GO:0016684 oxidoreductase activity, acting on peroxide as acceptor; ","K05022",null,null,"IPR010987; IPR004045; IPR012336; ","\"Glutathione S-transferase, C-terminal-like; Glutathione S-transferase, N-terminal; Thioredoxin-like fold; \"\r"]
["O15254","Peroxisomal acyl-coenzyme A oxidase 3 OS=Homo sapiens OX=9606 GN=ACOX3","ACOX3",77.628,17.481,9.7,5,6,5,1.001,0.937,1.054,1.035,0.999,0.982,1.008,0.824,"cytoplasm\r","GO:0034440 lipid oxidation; GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0030258 lipid modification; GO:0044248 cellular catabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0009987 cellular process; GO:0006629 lipid metabolic process; GO:0016042 lipid catabolic process; GO:0019395 fatty acid oxidation; GO:0055114 oxidation-reduction process; GO:0044712 single-organism catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006635 fatty acid beta-oxidation; GO:0072329 monocarboxylic acid catabolic process; GO:0044282 small molecule catabolic process; GO:0006631 fatty acid metabolic process; GO:0044238 primary metabolic process; GO:0046395 carboxylic acid catabolic process; GO:1901575 organic substance catabolic process; GO:0044710 single-organism metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0016054 organic acid catabolic process; GO:0044242 cellular lipid catabolic process; GO:0006082 organic acid metabolic process; GO:0009056 catabolic process; GO:0009062 fatty acid catabolic process; GO:0043436 oxoacid metabolic process; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044439 peroxisomal part; GO:0005777 peroxisome; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0044438 microbody part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031907 microbody lumen; GO:0070013 intracellular organelle lumen; GO:0005782 peroxisomal matrix; GO:0005622 intracellular; GO:0044464 cell part; GO:0042579 microbody; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; ","GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor; GO:1901265 nucleoside phosphate binding; GO:0050660 flavin adenine dinucleotide binding; GO:0005102 receptor binding; GO:0043167 ion binding; GO:0003997 acyl-CoA oxidase activity; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0048037 cofactor binding; GO:0016491 oxidoreductase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors; GO:0016402 pristanoyl-CoA oxidase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043168 anion binding; GO:0003995 acyl-CoA dehydrogenase activity; GO:0050662 coenzyme binding; GO:0036094 small molecule binding; ","K00232","E1.3.3.6; acyl-CoA oxidase [EC:1.3.3.6]","hsa03320 PPAR signaling pathway - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa01212 Fatty acid metabolism - Homo sapiens (human); hsa00592 alpha-Linolenic acid metabolism - Homo sapiens (human); hsa04146 Peroxisome - Homo sapiens (human); hsa04024 cAMP signaling pathway - Homo sapiens (human); hsa00071 Fatty acid degradation - Homo sapiens (human); hsa01040 Biosynthesis of unsaturated fatty acids - Homo sapiens (human); ","IPR009100; IPR006091; IPR002655; IPR009075; ","\"Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain; Acyl-CoA oxidase/dehydrogenase, central domain; Acyl-CoA oxidase, C-terminal; Acyl-CoA dehydrogenase/oxidase C-terminal; \"\r"]
["O15258","Protein RER1 OS=Homo sapiens OX=9606 GN=RER1","RER1",22.958,6.5448,5.6,1,2,1,0.935,0.995,0.911,1.059,1.097,1.007,1.113,0.0408,"plasma membrane\r","GO:0050794 regulation of cellular process; GO:0007528 neuromuscular junction development; GO:0016043 cellular component organization; GO:1903829 positive regulation of cellular protein localization; GO:1903076 regulation of protein localization to plasma membrane; GO:0048193 Golgi vesicle transport; GO:0044699 single-organism process; GO:0051668 localization within membrane; GO:1903078 positive regulation of protein localization to plasma membrane; GO:1905477 positive regulation of protein localization to membrane; GO:0070201 regulation of establishment of protein localization; GO:0051234 establishment of localization; GO:0060341 regulation of cellular localization; GO:0051130 positive regulation of cellular component organization; GO:1903729 regulation of plasma membrane organization; GO:0090004 positive regulation of establishment of protein localization to plasma membrane; GO:1905475 regulation of protein localization to membrane; GO:1904375 regulation of protein localization to cell periphery; GO:0032879 regulation of localization; GO:0032880 regulation of protein localization; GO:0034613 cellular protein localization; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0090003 regulation of establishment of protein localization to plasma membrane; GO:0009987 cellular process; GO:1904377 positive regulation of protein localization to cell periphery; GO:0072657 protein localization to membrane; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0044802 single-organism membrane organization; GO:0048522 positive regulation of cellular process; GO:0071340 skeletal muscle acetylcholine-gated channel clustering; GO:0050808 synapse organization; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0006810 transport; GO:0043113 receptor clustering; GO:0070727 cellular macromolecule localization; GO:0050789 regulation of biological process; GO:1904951 positive regulation of establishment of protein localization; GO:0006890 retrograde vesicle-mediated transport, Golgi to ER; GO:0061024 membrane organization; GO:0001941 postsynaptic membrane organization; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:1903827 regulation of cellular protein localization; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0098588 bounding membrane of organelle; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0000139 Golgi membrane; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0030173 integral component of Golgi membrane; GO:0005623 cell; GO:0031228 intrinsic component of Golgi membrane; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031301 integral component of organelle membrane; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005793 endoplasmic reticulum-Golgi intermediate compartment; GO:0044431 Golgi apparatus part; GO:0009986 cell surface; GO:0005794 Golgi apparatus; GO:0043227 membrane-bounded organelle; GO:0031300 intrinsic component of organelle membrane; GO:0044444 cytoplasmic part; ","GO:0033130 acetylcholine receptor binding; GO:0005515 protein binding; GO:0005102 receptor binding; GO:0005488 binding; "]
["O15260","Surfeit locus protein 4 OS=Homo sapiens OX=9606 GN=SURF4","SURF4",30.394,13.775,14.9,4,10,4,0.988,0.966,0.95,1.03,1.004,1.004,1.046,0.0335,"plasma membrane\r","GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0010256 endomembrane system organization; GO:0045321 leukocyte activation; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0048193 Golgi vesicle transport; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0002274 myeloid leukocyte activation; GO:0002443 leukocyte mediated immunity; GO:0016192 vesicle-mediated transport; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0033043 regulation of organelle organization; GO:0048522 positive regulation of cellular process; GO:0002376 immune system process; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0002263 cell activation involved in immune response; GO:0002444 myeloid leukocyte mediated immunity; GO:0002366 leukocyte activation involved in immune response; GO:0006810 transport; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0050789 regulation of biological process; GO:0010638 positive regulation of organelle organization; GO:0007030 Golgi organization; GO:0006890 retrograde vesicle-mediated transport, Golgi to ER; GO:0006996 organelle organization; GO:0032940 secretion by cell; GO:0001775 cell activation; GO:0051128 regulation of cellular component organization; GO:0043299 leukocyte degranulation; GO:0006955 immune response; GO:0051179 localization; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; GO:0006887 exocytosis; ","GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005765 lysosomal membrane; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:0044431 Golgi apparatus part; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0035577 azurophil granule membrane; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0098852 lytic vacuole membrane; GO:0042582 azurophil granule; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0030667 secretory granule membrane; GO:0044432 endoplasmic reticulum part; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005793 endoplasmic reticulum-Golgi intermediate compartment; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0030133 transport vesicle; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ","K20369"]
["O15264","Mitogen-activated protein kinase 13 OS=Homo sapiens OX=9606 GN=MAPK13","MAPK13",42.089,16.812,13.4,4,4,4,0.887,0.839,0.887,1.198,1.123,1.022,1.279,0.00794,"cytoplasm\r","GO:0044700 single organism signaling; GO:0007166 cell surface receptor signaling pathway; GO:0018209 peptidyl-serine modification; GO:0097659 nucleic acid-templated transcription; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0031347 regulation of defense response; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0007154 cell communication; GO:0051240 positive regulation of multicellular organismal process; GO:0032103 positive regulation of response to external stimulus; GO:0018105 peptidyl-serine phosphorylation; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0051716 cellular response to stimulus; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0006970 response to osmotic stress; GO:0031326 regulation of cellular biosynthetic process; GO:0050729 positive regulation of inflammatory response; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0023052 signaling; GO:0031323 regulation of cellular metabolic process; GO:0016070 RNA metabolic process; GO:0000165 MAPK cascade; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006464 cellular protein modification process; GO:0048010 vascular endothelial growth factor receptor signaling pathway; GO:0036211 protein modification process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016310 phosphorylation; GO:0006725 cellular aromatic compound metabolic process; GO:0001819 positive regulation of cytokine production; GO:0060255 regulation of macromolecule metabolic process; GO:0009628 response to abiotic stimulus; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0080134 regulation of response to stress; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:0071704 organic substance metabolic process; GO:0031349 positive regulation of defense response; GO:0046483 heterocycle metabolic process; GO:0006468 protein phosphorylation; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0023014 signal transduction by protein phosphorylation; GO:0032755 positive regulation of interleukin-6 production; GO:0006355 regulation of transcription, DNA-templated; GO:0006950 response to stress; GO:0035556 intracellular signal transduction; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0032675 regulation of interleukin-6 production; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0032101 regulation of response to external stimulus; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0018193 peptidyl-amino acid modification; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0050727 regulation of inflammatory response; GO:0001817 regulation of cytokine production; GO:0010467 gene expression; GO:0043412 macromolecule modification; GO:0048584 positive regulation of response to stimulus; GO:0007049 cell cycle; GO:0065007 biological regulation; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0005829 cytosol; GO:0044444 cytoplasmic part; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0004672 protein kinase activity; GO:0000166 nucleotide binding; GO:0004702 signal transducer, downstream of receptor, with serine/threonine kinase activity; GO:0004871 signal transducer activity; GO:0004707 MAP kinase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0005057 signal transducer activity, downstream of receptor; GO:0097367 carbohydrate derivative binding; GO:0016301 kinase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0004674 protein serine/threonine kinase activity; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0016740 transferase activity; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K04441","P38; p38 MAP kinase [EC:2.7.11.24]","hsa05152 Tuberculosis - Homo sapiens (human); hsa04015 Rap1 signaling pathway - Homo sapiens (human); hsa04625 C-type lectin receptor signaling pathway - Homo sapiens (human); hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa05131 Shigellosis - Homo sapiens (human); hsa05145 Toxoplasmosis - Homo sapiens (human); hsa04114 Oocyte meiosis - Homo sapiens (human); hsa05164 Influenza A - Homo sapiens (human); hsa04380 Osteoclast differentiation - Homo sapiens (human); hsa04071 Sphingolipid signaling pathway - Homo sapiens (human); hsa04933 AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human); hsa04659 Th17 cell differentiation - Homo sapiens (human); hsa05014 Amyotrophic lateral sclerosis (ALS) - Homo sapiens (human); hsa04611 Platelet activation - Homo sapiens (human); hsa04917 Prolactin signaling pathway - Homo sapiens (human); hsa01522 Endocrine resistance - Homo sapiens (human); hsa04914 Progesterone-mediated oocyte maturation - Homo sapiens (human); hsa05120 Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human); hsa05142 Chagas disease (American trypanosomiasis) - Homo sapiens (human); hsa05132 Salmonella infection - Homo sapiens (human); hsa04218 Cellular senescence - Homo sapiens (human); hsa04728 Dopaminergic synapse - Homo sapiens (human); hsa04620 Toll-like receptor signaling pathway - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); hsa04722 Neurotrophin signaling pathway - Homo sapiens (human); hsa04370 VEGF signaling pathway - Homo sapiens (human); hsa05160 Hepatitis C - Homo sapiens (human); hsa05140 Leishmaniasis - Homo sapiens (human); hsa05167 Kaposi's sarcoma-associated herpesvirus infection - Homo sapiens (human); hsa04010 MAPK signaling pathway - Homo sapiens (human); hsa04670 Leukocyte transendothelial migration - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human); hsa04660 T cell receptor signaling pathway - Homo sapiens (human); hsa04750 Inflammatory mediator regulation of TRP channels - Homo sapiens (human); hsa04658 Th1 and Th2 cell differentiation - Homo sapiens (human); hsa04664 Fc epsilon RI signaling pathway - Homo sapiens (human); hsa04657 IL-17 signaling pathway - Homo sapiens (human); hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human); hsa04912 GnRH signaling pathway - Homo sapiens (human); hsa04668 TNF signaling pathway - Homo sapiens (human); hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human); hsa04068 FoxO signaling pathway - Homo sapiens (human); hsa05133 Pertussis - Homo sapiens (human); hsa04622 RIG-I-like receptor signaling pathway - Homo sapiens (human); hsa04926 Relaxin signaling pathway - Homo sapiens (human); hsa04550 Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human); ","IPR000719; IPR011009; ","Protein kinase domain; Protein kinase-like domain; \r"]
["O15269","Serine palmitoyltransferase 1 OS=Homo sapiens OX=9606 GN=SPTLC1","SPTLC1",52.743,17.361,8.5,5,6,5,0.929,1.114,0.925,1.124,0.928,0.996,1.027,0.759,"cytoplasm\r","GO:0006667 sphinganine metabolic process; GO:0034311 diol metabolic process; GO:0006066 alcohol metabolic process; GO:0006643 membrane lipid metabolic process; GO:0006672 ceramide metabolic process; GO:0031331 positive regulation of cellular catabolic process; GO:0008654 phospholipid biosynthetic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0009058 biosynthetic process; GO:0019216 regulation of lipid metabolic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0008610 lipid biosynthetic process; GO:0008152 metabolic process; GO:0030148 sphingolipid biosynthetic process; GO:0009893 positive regulation of metabolic process; GO:0046511 sphinganine biosynthetic process; GO:0050996 positive regulation of lipid catabolic process; GO:0006665 sphingolipid metabolic process; GO:0006629 lipid metabolic process; GO:0006670 sphingosine metabolic process; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0044281 small molecule metabolic process; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:1901617 organic hydroxy compound biosynthetic process; GO:0043603 cellular amide metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0010506 regulation of autophagy; GO:0090407 organophosphate biosynthetic process; GO:0016241 regulation of macroautophagy; GO:0050789 regulation of biological process; GO:0006686 sphingomyelin biosynthetic process; GO:0044710 single-organism metabolic process; GO:0010508 positive regulation of autophagy; GO:0019222 regulation of metabolic process; GO:0016239 positive regulation of macroautophagy; GO:0050994 regulation of lipid catabolic process; GO:0050794 regulation of cellular process; GO:1901615 organic hydroxy compound metabolic process; GO:0097164 ammonium ion metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0046520 sphingoid biosynthetic process; GO:0009896 positive regulation of catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:1904502 regulation of lipophagy; GO:0009987 cellular process; GO:0046467 membrane lipid biosynthetic process; GO:0046519 sphingoid metabolic process; GO:0034312 diol biosynthetic process; GO:0044711 single-organism biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0046165 alcohol biosynthetic process; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0019751 polyol metabolic process; GO:1901576 organic substance biosynthetic process; GO:0045834 positive regulation of lipid metabolic process; GO:0044249 cellular biosynthetic process; GO:0006684 sphingomyelin metabolic process; GO:1904504 positive regulation of lipophagy; GO:0046512 sphingosine biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0044283 small molecule biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0046173 polyol biosynthetic process; GO:0006644 phospholipid metabolic process; GO:0043604 amide biosynthetic process; GO:0046513 ceramide biosynthetic process; GO:0065007 biological regulation; GO:1901564 organonitrogen compound metabolic process; ","GO:0002178 palmitoyltransferase complex; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:1990234 transferase complex; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:1902494 catalytic complex; GO:0035339 SPOTS complex; GO:0031211 endoplasmic reticulum palmitoyltransferase complex; GO:0044432 endoplasmic reticulum part; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0017059 serine C-palmitoyltransferase complex; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; ","GO:0043167 ion binding; GO:0005515 protein binding; GO:0004758 serine C-palmitoyltransferase activity; GO:0016409 palmitoyltransferase activity; GO:0048037 cofactor binding; GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups; GO:0030170 pyridoxal phosphate binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016746 transferase activity, transferring acyl groups; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043168 anion binding; GO:0016408 C-acyltransferase activity; GO:0016454 C-palmitoyltransferase activity; GO:0016740 transferase activity; ","K00654","SPT; serine palmitoyltransferase [EC:2.3.1.50]","hsa04071 Sphingolipid signaling pathway - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00600 Sphingolipid metabolism - Homo sapiens (human); ","IPR004839; IPR015424; IPR015422; IPR015421; ","\"Aminotransferase, class I/classII; Pyridoxal phosphate-dependent transferase; Pyridoxal phosphate-dependent transferase, major region, subdomain 2; Pyridoxal phosphate-dependent transferase, major region, subdomain 1; \"\r"]
["O15296","Arachidonate 15-lipoxygenase B OS=Homo sapiens OX=9606 GN=ALOX15B","ALOX15B",75.856,81.061,16,9,15,9,1.295,1.263,1.183,0.764,0.769,0.737,0.607,7.84e-05,"nucleus\r","GO:0010744 positive regulation of macrophage derived foam cell differentiation; GO:0048732 gland development; GO:0022414 reproductive process; GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway; GO:0035358 regulation of peroxisome proliferator activated receptor signaling pathway; GO:0044255 cellular lipid metabolic process; GO:0030858 positive regulation of epithelial cell differentiation; GO:0044237 cellular metabolic process; GO:0008610 lipid biosynthetic process; GO:0008285 negative regulation of cell proliferation; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0045682 regulation of epidermis development; GO:0032879 regulation of localization; GO:0044702 single organism reproductive process; GO:0032787 monocarboxylic acid metabolic process; GO:0006690 icosanoid metabolic process; GO:0003006 developmental process involved in reproduction; GO:0043651 linoleic acid metabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0050707 regulation of cytokine secretion; GO:2000146 negative regulation of cell motility; GO:0032501 multicellular organismal process; GO:0030856 regulation of epithelial cell differentiation; GO:0048513 animal organ development; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:0050714 positive regulation of protein secretion; GO:0051223 regulation of protein transport; GO:0051094 positive regulation of developmental process; GO:0043436 oxoacid metabolic process; GO:0051047 positive regulation of secretion; GO:0050794 regulation of cellular process; GO:0033559 unsaturated fatty acid metabolic process; GO:0000003 reproduction; GO:0044707 single-multicellular organism process; GO:0019369 arachidonic acid metabolic process; GO:0042759 long-chain fatty acid biosynthetic process; GO:0042127 regulation of cell proliferation; GO:0001819 positive regulation of cytokine production; GO:0030850 prostate gland development; GO:0045604 regulation of epidermal cell differentiation; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0051239 regulation of multicellular organismal process; GO:0045597 positive regulation of cell differentiation; GO:2000145 regulation of cell motility; GO:0032880 regulation of protein localization; GO:0090196 regulation of chemokine secretion; GO:0007275 multicellular organism development; GO:0061458 reproductive system development; GO:0009966 regulation of signal transduction; GO:0044711 single-organism biosynthetic process; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0030334 regulation of cell migration; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0045606 positive regulation of epidermal cell differentiation; GO:0045618 positive regulation of keratinocyte differentiation; GO:1904951 positive regulation of establishment of protein localization; GO:0030336 negative regulation of cell migration; GO:0001676 long-chain fatty acid metabolic process; GO:0044283 small molecule biosynthetic process; GO:0012501 programmed cell death; GO:0048584 positive regulation of response to stimulus; GO:0072330 monocarboxylic acid biosynthetic process; GO:0050793 regulation of developmental process; GO:0051122 hepoxilin biosynthetic process; GO:0016053 organic acid biosynthetic process; GO:0023051 regulation of signaling; GO:1901568 fatty acid derivative metabolic process; GO:0044699 single-organism process; GO:0051046 regulation of secretion; GO:0009058 biosynthetic process; GO:0040013 negative regulation of locomotion; GO:0010646 regulation of cell communication; GO:0032642 regulation of chemokine production; GO:0006915 apoptotic process; GO:0019372 lipoxygenase pathway; GO:0051726 regulation of cell cycle; GO:0006629 lipid metabolic process; GO:0032502 developmental process; GO:0045926 negative regulation of growth; GO:0010743 regulation of macrophage derived foam cell differentiation; GO:0055114 oxidation-reduction process; GO:0048608 reproductive structure development; GO:0048522 positive regulation of cellular process; GO:0006636 unsaturated fatty acid biosynthetic process; GO:1903530 regulation of secretion by cell; GO:0006633 fatty acid biosynthetic process; GO:0051050 positive regulation of transport; GO:0001655 urogenital system development; GO:0046394 carboxylic acid biosynthetic process; GO:0050789 regulation of biological process; GO:1903532 positive regulation of secretion by cell; GO:0045616 regulation of keratinocyte differentiation; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:0050715 positive regulation of cytokine secretion; GO:0051222 positive regulation of protein transport; GO:0032722 positive regulation of chemokine production; GO:2000026 regulation of multicellular organismal development; GO:0051271 negative regulation of cellular component movement; GO:0045786 negative regulation of cell cycle; GO:0045684 positive regulation of epidermis development; GO:0040008 regulation of growth; GO:0070201 regulation of establishment of protein localization; GO:0071704 organic substance metabolic process; GO:0023056 positive regulation of signaling; GO:0010647 positive regulation of cell communication; GO:0050708 regulation of protein secretion; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0090197 positive regulation of chemokine secretion; GO:0051049 regulation of transport; GO:0006631 fatty acid metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0051121 hepoxilin metabolic process; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0019752 carboxylic acid metabolic process; GO:0001817 regulation of cytokine production; GO:0009967 positive regulation of signal transduction; GO:0040012 regulation of locomotion; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0019898 extrinsic component of membrane; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043228 non-membrane-bounded organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005634 nucleus; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005506 iron ion binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0016165 linoleate 13S-lipoxygenase activity; GO:0016491 oxidoreductase activity; GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; GO:0036403 arachidonate 8(S)-lipoxygenase activity; GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0051213 dioxygenase activity; GO:0008289 lipid binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005509 calcium ion binding; GO:0050473 arachidonate 15-lipoxygenase activity; ","K08022","ALOX15B; arachidonate 15-lipoxygenase (second type) / 8-lipoxygenase (S-type) [EC:1.13.11.33 1.13.11.-]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa04726 Serotonergic synapse - Homo sapiens (human); hsa00590 Arachidonic acid metabolism - Homo sapiens (human); ","IPR001024; IPR013819; ","\"PLAT/LH2 domain; Lipoxygenase, C-terminal; \"\r"]
["O15305","Phosphomannomutase 2 OS=Homo sapiens OX=9606 GN=PMM2","PMM2",28.082,9.2449,20.7,5,7,5,0.906,0.961,0.979,1.091,1.035,1.018,1.105,0.0335,"cytoplasm\r","GO:0009226 nucleotide-sugar biosynthetic process; GO:0043413 macromolecule glycosylation; GO:0072594 establishment of protein localization to organelle; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:1901137 carbohydrate derivative biosynthetic process; GO:0070972 protein localization to endoplasmic reticulum; GO:0009298 GDP-mannose biosynthetic process; GO:0033365 protein localization to organelle; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006487 protein N-linked glycosylation; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0006486 protein glycosylation; GO:0009101 glycoprotein biosynthetic process; GO:0018130 heterocycle biosynthetic process; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0009100 glycoprotein metabolic process; GO:0045047 protein targeting to ER; GO:0005975 carbohydrate metabolic process; GO:0006810 transport; GO:0044723 single-organism carbohydrate metabolic process; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0036211 protein modification process; GO:1901362 organic cyclic compound biosynthetic process; GO:0046907 intracellular transport; GO:0006725 cellular aromatic compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0006013 mannose metabolic process; GO:0071704 organic substance metabolic process; GO:0019673 GDP-mannose metabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0005996 monosaccharide metabolic process; GO:0006886 intracellular protein transport; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034613 cellular protein localization; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0070085 glycosylation; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0009225 nucleotide-sugar metabolic process; GO:0051179 localization; GO:0043412 macromolecule modification; GO:0019318 hexose metabolic process; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0043025 neuronal cell body; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0036477 somatodendritic compartment; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0044297 cell body; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0004615 phosphomannomutase activity; GO:0016853 isomerase activity; GO:0016866 intramolecular transferase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016868 intramolecular transferase activity, phosphotransferases; ","K17497","PMM; phosphomannomutase [EC:5.4.2.8]","hsa00051 Fructose and mannose metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00520 Amino sugar and nucleotide sugar metabolism - Homo sapiens (human); ","IPR023214; ","HAD-like domain; \r"]
["O15321","Transmembrane 9 superfamily member 1 OS=Homo sapiens OX=9606 GN=TM9SF1","TM9SF1",68.86,1.8636,1.3,1,1,1,1.25,0.791,0.766,1.046,1.055,1.096,1.139,0.429,"plasma membrane\r","GO:0044248 cellular catabolic process; GO:0008152 metabolic process; GO:0006914 autophagy; GO:0009056 catabolic process; GO:0044237 cellular metabolic process; GO:0009987 cellular process; ","GO:0016020 membrane; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005776 autophagosome; GO:0005765 lysosomal membrane; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0098805 whole membrane; GO:0005764 lysosome; GO:0043227 membrane-bounded organelle; GO:0000421 autophagosome membrane; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0016021 integral component of membrane; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0044444 cytoplasmic part; ",null,"K17085"]
["O15355","Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G","PPM1G",59.271,24.879,12.1,6,9,6,0.935,0.918,0.882,1.101,1.187,1.032,1.214,0.0119,"nucleus\r","GO:0050794 regulation of cellular process; GO:0045786 negative regulation of cell cycle; GO:0007050 cell cycle arrest; GO:0044267 cellular protein metabolic process; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0035970 peptidyl-threonine dephosphorylation; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0006470 protein dephosphorylation; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0016311 dephosphorylation; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0050789 regulation of biological process; GO:0006793 phosphorus metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0022402 cell cycle process; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:0051726 regulation of cell cycle; GO:0009987 cellular process; GO:0007049 cell cycle; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0042578 phosphoric ester hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0004722 protein serine/threonine phosphatase activity; GO:0016791 phosphatase activity; GO:0043167 ion binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0004721 phosphoprotein phosphatase activity; ","K17499",null,null,"IPR001932; ","PPM-type phosphatase domain; \r"]
["O15371","Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D","EIF3D",63.972,79.116,30.1,11,13,11,0.931,0.896,1.04,1.079,1.078,1.053,1.12,0.0645,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0075522 IRES-dependent viral translational initiation; GO:0022613 ribonucleoprotein complex biogenesis; GO:1905216 positive regulation of RNA binding; GO:0075525 viral translational termination-reinitiation; GO:0032270 positive regulation of cellular protein metabolic process; GO:0006518 peptide metabolic process; GO:0022618 ribonucleoprotein complex assembly; GO:0010608 posttranscriptional regulation of gene expression; GO:0009891 positive regulation of biosynthetic process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0071826 ribonucleoprotein complex subunit organization; GO:0002181 cytoplasmic translation; GO:0022607 cellular component assembly; GO:0009893 positive regulation of metabolic process; GO:0065003 macromolecular complex assembly; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0044093 positive regulation of molecular function; GO:0006413 translational initiation; GO:0002190 cap-independent translational initiation; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006412 translation; GO:0044419 interspecies interaction between organisms; GO:0051099 positive regulation of binding; GO:0002183 cytoplasmic translational initiation; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0045727 positive regulation of translation; GO:0043043 peptide biosynthetic process; GO:0051098 regulation of binding; GO:0048522 positive regulation of cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0043603 cellular amide metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0051704 multi-organism process; GO:1902415 regulation of mRNA binding; GO:0002191 cap-dependent translational initiation; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0065009 regulation of molecular function; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:1905214 regulation of RNA binding; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0019081 viral translation; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0044267 cellular protein metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:1902416 positive regulation of mRNA binding; GO:0071704 organic substance metabolic process; GO:0016032 viral process; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0019080 viral gene expression; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0034622 cellular macromolecular complex assembly; GO:0002192 IRES-dependent translational initiation; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0034248 regulation of cellular amide metabolic process; GO:0051247 positive regulation of protein metabolic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006417 regulation of translation; GO:0051246 regulation of protein metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0034250 positive regulation of cellular amide metabolic process; GO:0001732 formation of cytoplasmic translation initiation complex; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0043234 protein complex; GO:0005623 cell; GO:0044444 cytoplasmic part; GO:0005852 eukaryotic translation initiation factor 3 complex; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0008135 translation factor activity, RNA binding; GO:0098808 mRNA cap binding; GO:0003723 RNA binding; GO:0003729 mRNA binding; GO:0000339 RNA cap binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0003743 translation initiation factor activity; GO:0005515 protein binding; ","K03251","EIF3D; translation initiation factor 3 subunit D","hsa03013 RNA transport - Homo sapiens (human); "]
["O15372","Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H","EIF3H",39.93,45.633,28.7,9,14,9,0.901,0.916,0.962,1.099,1.097,1.073,1.176,0.00152,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0006518 peptide metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0010608 posttranscriptional regulation of gene expression; GO:0044267 cellular protein metabolic process; GO:0009058 biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0009889 regulation of biosynthetic process; GO:0006413 translational initiation; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006412 translation; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0043043 peptide biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0043603 cellular amide metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0034248 regulation of cellular amide metabolic process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0051246 regulation of protein metabolic process; GO:0006417 regulation of translation; GO:0044260 cellular macromolecule metabolic process; GO:0006446 regulation of translational initiation; GO:0019222 regulation of metabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0065007 biological regulation; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0005852 eukaryotic translation initiation factor 3 complex; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0008135 translation factor activity, RNA binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0003743 translation initiation factor activity; GO:0005515 protein binding; ","K03247","EIF3H; translation initiation factor 3 subunit H","hsa05162 Measles - Homo sapiens (human); hsa03013 RNA transport - Homo sapiens (human); ","IPR000555; ","JAB1/MPN/MOV34 metalloenzyme domain; \r"]
["O15382","Branched-chain-amino-acid aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=BCAT2","BCAT2",44.287,56.541,16.3,5,6,5,1.129,1.031,1.062,1.132,0.834,0.869,0.88,0.241,"mitochondria\r","GO:1901606 alpha-amino acid catabolic process; GO:0065008 regulation of biological quality; GO:0016053 organic acid biosynthetic process; GO:0009082 branched-chain amino acid biosynthetic process; GO:0009098 leucine biosynthetic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:0006573 valine metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:1901607 alpha-amino acid biosynthetic process; GO:0044248 cellular catabolic process; GO:0009081 branched-chain amino acid metabolic process; GO:0009987 cellular process; GO:0008652 cellular amino acid biosynthetic process; GO:0044711 single-organism biosynthetic process; GO:0044712 single-organism catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0009099 valine biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0044282 small molecule catabolic process; GO:0044238 primary metabolic process; GO:1901605 alpha-amino acid metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0046395 carboxylic acid catabolic process; GO:0009083 branched-chain amino acid catabolic process; GO:1901575 organic substance catabolic process; GO:0046394 carboxylic acid biosynthetic process; GO:1901565 organonitrogen compound catabolic process; GO:0006551 leucine metabolic process; GO:0006549 isoleucine metabolic process; GO:0044710 single-organism metabolic process; GO:0016054 organic acid catabolic process; GO:0044283 small molecule biosynthetic process; GO:0019752 carboxylic acid metabolic process; GO:0010817 regulation of hormone levels; GO:0009063 cellular amino acid catabolic process; GO:0006082 organic acid metabolic process; GO:0009056 catabolic process; GO:0043436 oxoacid metabolic process; GO:0006550 isoleucine catabolic process; GO:0065007 biological regulation; GO:1901564 organonitrogen compound metabolic process; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0052654 L-leucine transaminase activity; GO:0016769 transferase activity, transferring nitrogenous groups; GO:0003824 catalytic activity; GO:0052655 L-valine transaminase activity; GO:0004084 branched-chain-amino-acid transaminase activity; GO:0052656 L-isoleucine transaminase activity; GO:0008483 transaminase activity; GO:0016740 transferase activity; ","K00826","E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]","hsa01210 2-Oxocarboxylic acid metabolism - Homo sapiens (human); hsa00280 Valine, leucine and isoleucine degradation - Homo sapiens (human); hsa00290 Valine, leucine and isoleucine biosynthesis - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00270 Cysteine and methionine metabolism - Homo sapiens (human); hsa00770 Pantothenate and CoA biosynthesis - Homo sapiens (human); hsa01230 Biosynthesis of amino acids - Homo sapiens (human); "]
["O15397","Importin-8 OS=Homo sapiens OX=9606 GN=IPO8","IPO8",119.94,7.6506,1.4,1,1,1,0.887,0.958,1.081,0.975,1.055,1.044,1.051,0.453,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0046907 intracellular transport; GO:0060255 regulation of macromolecule metabolic process; GO:0044699 single-organism process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0006886 intracellular protein transport; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0051716 cellular response to stimulus; GO:0010468 regulation of gene expression; GO:0010629 negative regulation of gene expression; GO:0044763 single-organism cellular process; GO:0071702 organic substance transport; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0009892 negative regulation of metabolic process; GO:0051641 cellular localization; GO:0006810 transport; GO:0045184 establishment of protein localization; GO:0016458 gene silencing; GO:0070727 cellular macromolecule localization; GO:0050789 regulation of biological process; GO:0031047 gene silencing by RNA; GO:0019222 regulation of metabolic process; GO:0051179 localization; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0031267 small GTPase binding; GO:0017016 Ras GTPase binding; GO:0005488 binding; GO:0005515 protein binding; GO:0008536 Ran GTPase binding; GO:0051020 GTPase binding; GO:0019899 enzyme binding; ","K18755",null,null,"IPR001494; IPR011989; IPR016024; IPR013713; ","\"Importin-beta, N-terminal domain; Armadillo-like helical; Armadillo-type fold; Exportin/Importin, Cse1-like; \"\r"]
["O15400","Syntaxin-7 OS=Homo sapiens OX=9606 GN=STX7","STX7",29.815,32.57,33.7,7,8,7,1.04,1.024,1.036,0.945,1.007,0.931,0.93,0.0406,"plasma membrane\r","GO:0044085 cellular component biogenesis; GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0044699 single-organism process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0031343 positive regulation of cell killing; GO:1903729 regulation of plasma membrane organization; GO:1904375 regulation of protein localization to cell periphery; GO:0051649 establishment of localization in cell; GO:0022607 cellular component assembly; GO:0032879 regulation of localization; GO:0002819 regulation of adaptive immune response; GO:1902683 regulation of receptor localization to synapse; GO:0044801 single-organism membrane fusion; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0002697 regulation of immune effector process; GO:0002708 positive regulation of lymphocyte mediated immunity; GO:0002709 regulation of T cell mediated immunity; GO:0044763 single-organism cellular process; GO:0061025 membrane fusion; GO:0050776 regulation of immune response; GO:0006810 transport; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0002705 positive regulation of leukocyte mediated immunity; GO:0048583 regulation of response to stimulus; GO:0065009 regulation of molecular function; GO:0006906 vesicle fusion; GO:0002682 regulation of immune system process; GO:0002821 positive regulation of adaptive immune response; GO:0051640 organelle localization; GO:0050794 regulation of cellular process; GO:0090174 organelle membrane fusion; GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0031341 regulation of cell killing; GO:1903076 regulation of protein localization to plasma membrane; GO:0002706 regulation of lymphocyte mediated immunity; GO:0022406 membrane docking; GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0001912 positive regulation of leukocyte mediated cytotoxicity; GO:0060341 regulation of cellular localization; GO:1905475 regulation of protein localization to membrane; GO:0070925 organelle assembly; GO:0001914 regulation of T cell mediated cytotoxicity; GO:0006886 intracellular protein transport; GO:0032880 regulation of protein localization; GO:1902685 positive regulation of receptor localization to synapse; GO:0034613 cellular protein localization; GO:0001916 positive regulation of T cell mediated cytotoxicity; GO:0009987 cellular process; GO:0050778 positive regulation of immune response; GO:0001910 regulation of leukocyte mediated cytotoxicity; GO:0002699 positive regulation of immune effector process; GO:0016192 vesicle-mediated transport; GO:0044802 single-organism membrane organization; GO:0016050 vesicle organization; GO:0048284 organelle fusion; GO:0071702 organic substance transport; GO:0048278 vesicle docking; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0002703 regulation of leukocyte mediated immunity; GO:0070727 cellular macromolecule localization; GO:0002711 positive regulation of T cell mediated immunity; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0002684 positive regulation of immune system process; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:1903827 regulation of cellular protein localization; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0031224 intrinsic component of membrane; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0055037 recycling endosome; GO:0005765 lysosomal membrane; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0098805 whole membrane; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0005768 endosome; GO:0030141 secretory granule; GO:0031901 early endosome membrane; GO:0030139 endocytic vesicle; GO:0043227 membrane-bounded organelle; GO:0031201 SNARE complex; GO:0000323 lytic vacuole; GO:0010008 endosome membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0005770 late endosome; GO:0098588 bounding membrane of organelle; GO:0070820 tertiary granule; GO:0044446 intracellular organelle part; GO:0044440 endosomal part; GO:0012505 endomembrane system; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0042582 azurophil granule; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044459 plasma membrane part; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0001772 immunological synapse; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005484 SNAP receptor activity; GO:0000149 SNARE binding; GO:0008200 ion channel inhibitor activity; GO:0016247 channel regulator activity; GO:0005488 binding; GO:0099106 ion channel regulator activity; GO:0005515 protein binding; GO:0019869 chloride channel inhibitor activity; GO:0098772 molecular function regulator; GO:0019905 syntaxin binding; GO:0016248 channel inhibitor activity; GO:0017081 chloride channel regulator activity; ","K08488","STX7; syntaxin 7","hsa04130 SNARE interactions in vesicular transport - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); ","IPR000727; IPR010989; IPR006011; ","\"Target SNARE coiled-coil homology domain; SNARE; Syntaxin, N-terminal domain; \"\r"]
["O15431","High affinity copper uptake protein 1 OS=Homo sapiens OX=9606 GN=SLC31A1","SLC31A1",21.09,2.7635,5.8,1,1,1,0.923,0.843,1.143,1.05,0.997,1.042,1.062,0.499,"plasma membrane\r","GO:0065008 regulation of biological quality; GO:0034220 ion transmembrane transport; GO:0055076 transition metal ion homeostasis; GO:0072718 response to cisplatin; GO:0030001 metal ion transport; GO:0030003 cellular cation homeostasis; GO:0035434 copper ion transmembrane transport; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:1902861 copper ion import into cell; GO:0055082 cellular chemical homeostasis; GO:0051234 establishment of localization; GO:0042493 response to drug; GO:0000041 transition metal ion transport; GO:0042592 homeostatic process; GO:1902578 single-organism localization; GO:0006812 cation transport; GO:0055080 cation homeostasis; GO:0098659 inorganic cation import into cell; GO:0055065 metal ion homeostasis; GO:0072719 cellular response to cisplatin; GO:0015677 copper ion import; GO:0009987 cellular process; GO:0070887 cellular response to chemical stimulus; GO:0048878 chemical homeostasis; GO:0044765 single-organism transport; GO:0006855 drug transmembrane transport; GO:0051716 cellular response to stimulus; GO:0099587 inorganic ion import into cell; GO:0006878 cellular copper ion homeostasis; GO:0098655 cation transmembrane transport; GO:0050801 ion homeostasis; GO:0098660 inorganic ion transmembrane transport; GO:0006825 copper ion transport; GO:0044763 single-organism cellular process; GO:0098771 inorganic ion homeostasis; GO:0019725 cellular homeostasis; GO:0098657 import into cell; GO:0046916 cellular transition metal ion homeostasis; GO:0055070 copper ion homeostasis; GO:0006810 transport; GO:0055085 transmembrane transport; GO:0042221 response to chemical; GO:0006873 cellular ion homeostasis; GO:0006811 ion transport; GO:0015893 drug transport; GO:0006875 cellular metal ion homeostasis; GO:0051179 localization; GO:0098662 inorganic cation transmembrane transport; GO:0065007 biological regulation; ","GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0031226 intrinsic component of plasma membrane; GO:0005770 late endosome; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0043025 neuronal cell body; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0055037 recycling endosome; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0044459 plasma membrane part; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005768 endosome; GO:0044297 cell body; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0044444 cytoplasmic part; ","GO:0046873 metal ion transmembrane transporter activity; GO:0015075 ion transmembrane transporter activity; GO:0015088 copper uptake transmembrane transporter activity; GO:0005375 copper ion transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0046915 transition metal ion transmembrane transporter activity; GO:0022890 inorganic cation transmembrane transporter activity; GO:0008324 cation transmembrane transporter activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0022857 transmembrane transporter activity; GO:0005215 transporter activity; ","K14686","SLC31A1; solute carrier family 31 (copper transporter), member 1","hsa01524 Platinum drug resistance - Homo sapiens (human); hsa04978 Mineral absorption - Homo sapiens (human); "]
["O15460","Prolyl 4-hydroxylase subunit alpha-2 OS=Homo sapiens OX=9606 GN=P4HA2","P4HA2",60.901,3.8552,4.5,2,2,2,1.229,1.087,1.211,0.86,0.791,0.851,0.709,0.00186,"extracellular\r","GO:0019511 peptidyl-proline hydroxylation; GO:0055114 oxidation-reduction process; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0018208 peptidyl-proline modification; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0018193 peptidyl-amino acid modification; GO:0008152 metabolic process; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:0009987 cellular process; GO:0018126 protein hydroxylation; ","GO:0005788 endoplasmic reticulum lumen; GO:0043229 intracellular organelle; GO:0005783 endoplasmic reticulum; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044432 endoplasmic reticulum part; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0019842 vitamin binding; GO:0005506 iron ion binding; GO:0031418 L-ascorbic acid binding; GO:0031543 peptidyl-proline dioxygenase activity; GO:0043167 ion binding; GO:0043177 organic acid binding; GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; GO:0005515 protein binding; GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; GO:0004656 procollagen-proline 4-dioxygenase activity; GO:0048029 monosaccharide binding; GO:0016491 oxidoreductase activity; GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; GO:0009055 electron carrier activity; GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen; GO:0031406 carboxylic acid binding; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0019798 procollagen-proline dioxygenase activity; GO:0051213 dioxygenase activity; GO:0005488 binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0030246 carbohydrate binding; GO:0043168 anion binding; GO:0031545 peptidyl-proline 4-dioxygenase activity; GO:0036094 small molecule binding; ","K00472","P4HA; prolyl 4-hydroxylase [EC:1.14.11.2]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00330 Arginine and proline metabolism - Homo sapiens (human); ","IPR006620; IPR011990; IPR005123; IPR013547; IPR013026; ","\"Prolyl 4-hydroxylase, alpha subunit; Tetratricopeptide-like helical domain; Oxoglutarate/iron-dependent dioxygenase; Prolyl 4-hydroxylase alpha-subunit, N-terminal; Tetratricopeptide repeat-containing domain; \"\r"]
["O15498","Synaptobrevin homolog YKT6 OS=Homo sapiens OX=9606 GN=YKT6","YKT6",22.417,23.016,23.7,4,8,4,1.021,1.033,0.962,1.032,0.993,0.97,0.993,0.822,"cytoplasm\r","GO:0051640 organelle localization; GO:0016043 cellular component organization; GO:0090174 organelle membrane fusion; GO:0046907 intracellular transport; GO:0048193 Golgi vesicle transport; GO:0044699 single-organism process; GO:0006903 vesicle targeting; GO:0022406 membrane docking; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0051649 establishment of localization in cell; GO:1902578 single-organism localization; GO:0051648 vesicle localization; GO:0044801 single-organism membrane fusion; GO:0016482 cytosolic transport; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0009987 cellular process; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0051650 establishment of vesicle localization; GO:0006904 vesicle docking involved in exocytosis; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0044802 single-organism membrane organization; GO:0016050 vesicle organization; GO:0061025 membrane fusion; GO:0048284 organelle fusion; GO:0071702 organic substance transport; GO:0051656 establishment of organelle localization; GO:0048278 vesicle docking; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:0016197 endosomal transport; GO:1902589 single-organism organelle organization; GO:0042147 retrograde transport, endosome to Golgi; GO:0006996 organelle organization; GO:0032940 secretion by cell; GO:0061024 membrane organization; GO:0006906 vesicle fusion; GO:0051179 localization; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0071840 cellular component organization or biogenesis; GO:0006887 exocytosis; ","GO:0030425 dendrite; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0098796 membrane protein complex; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0043025 neuronal cell body; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0043005 neuron projection; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0031201 SNARE complex; GO:0097458 neuron part; GO:0097441 basilar dendrite; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0042995 cell projection; GO:0031226 intrinsic component of plasma membrane; GO:0098588 bounding membrane of organelle; GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0036477 somatodendritic compartment; GO:0044459 plasma membrane part; GO:0097440 apical dendrite; GO:0005793 endoplasmic reticulum-Golgi intermediate compartment; GO:0044297 cell body; GO:0030133 transport vesicle; GO:0005794 Golgi apparatus; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016417 S-acyltransferase activity; GO:0005484 SNAP receptor activity; GO:0000149 SNARE binding; GO:0050839 cell adhesion molecule binding; GO:0016746 transferase activity, transferring acyl groups; GO:0003824 catalytic activity; GO:0019706 protein-cysteine S-palmitoyltransferase activity; GO:0005488 binding; GO:0045296 cadherin binding; GO:0019707 protein-cysteine S-acyltransferase activity; GO:0005515 protein binding; GO:0016409 palmitoyltransferase activity; GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups; GO:0016740 transferase activity; ","K08516","YKT6; synaptobrevin homolog YKT6","hsa04130 SNARE interactions in vesicular transport - Homo sapiens (human); ","IPR010908; IPR011012; IPR001388; ","Longin domain; Longin-like domain; Synaptobrevin; \r"]
["O15511","Actin-related protein 2/3 complex subunit 5 OS=Homo sapiens OX=9606 GN=ARPC5","ARPC5",16.32,60.565,47,7,10,7,0.965,0.94,0.911,0.987,1.113,1.061,1.123,0.0414,"cytoplasm\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0007166 cell surface receptor signaling pathway; GO:0007420 brain development; GO:0030832 regulation of actin filament length; GO:0030036 actin cytoskeleton organization; GO:0032535 regulation of cellular component size; GO:0051493 regulation of cytoskeleton organization; GO:0021769 orbitofrontal cortex development; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0007163 establishment or maintenance of cell polarity; GO:0048870 cell motility; GO:0032501 multicellular organismal process; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0000226 microtubule cytoskeleton organization; GO:0048513 animal organ development; GO:0007417 central nervous system development; GO:0048583 regulation of response to stimulus; GO:0002682 regulation of immune system process; GO:1902905 positive regulation of supramolecular fiber organization; GO:0097435 supramolecular fiber organization; GO:1902903 regulation of supramolecular fiber organization; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0002283 neutrophil activation involved in immune response; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0032956 regulation of actin cytoskeleton organization; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0030900 forebrain development; GO:0007275 multicellular organism development; GO:0038093 Fc receptor signaling pathway; GO:0007010 cytoskeleton organization; GO:0050778 positive regulation of immune response; GO:0002253 activation of immune response; GO:0051495 positive regulation of cytoskeleton organization; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0032970 regulation of actin filament-based process; GO:0007017 microtubule-based process; GO:0002263 cell activation involved in immune response; GO:0030838 positive regulation of actin filament polymerization; GO:0008064 regulation of actin polymerization or depolymerization; GO:0045055 regulated exocytosis; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0030029 actin filament-based process; GO:0001775 cell activation; GO:0006928 movement of cell or subcellular component; GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis; GO:0048584 positive regulation of response to stimulus; GO:0006955 immune response; GO:0051179 localization; GO:0006887 exocytosis; GO:0030833 regulation of actin filament polymerization; GO:0097581 lamellipodium organization; GO:0034314 Arp2/3 complex-mediated actin nucleation; GO:0032273 positive regulation of protein polymerization; GO:0051674 localization of cell; GO:0038094 Fc-gamma receptor signaling pathway; GO:0044699 single-organism process; GO:0021761 limbic system development; GO:0051234 establishment of localization; GO:0006909 phagocytosis; GO:0051130 positive regulation of cellular component organization; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0045010 actin nucleation; GO:0032271 regulation of protein polymerization; GO:0031334 positive regulation of protein complex assembly; GO:0060322 head development; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0030011 maintenance of cell polarity; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis; GO:0002446 neutrophil mediated immunity; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0002764 immune response-regulating signaling pathway; GO:0002444 myeloid leukocyte mediated immunity; GO:1902589 single-organism organelle organization; GO:0043254 regulation of protein complex assembly; GO:0050789 regulation of biological process; GO:0030030 cell projection organization; GO:0010638 positive regulation of organelle organization; GO:0032940 secretion by cell; GO:0040011 locomotion; GO:0043299 leukocyte degranulation; GO:0002431 Fc receptor mediated stimulatory signaling pathway; GO:0048856 anatomical structure development; GO:0016477 cell migration; GO:0016043 cellular component organization; GO:0014909 smooth muscle cell migration; GO:0002252 immune effector process; GO:0007015 actin filament organization; GO:0044087 regulation of cellular component biogenesis; GO:0050896 response to stimulus; GO:0048013 ephrin receptor signaling pathway; GO:0002757 immune response-activating signal transduction; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0033043 regulation of organelle organization; GO:0043312 neutrophil degranulation; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0002366 leukocyte activation involved in immune response; GO:0051639 actin filament network formation; GO:0042119 neutrophil activation; GO:0044767 single-organism developmental process; GO:0031023 microtubule organizing center organization; GO:0002684 positive regulation of immune system process; GO:0090066 regulation of anatomical structure size; GO:0014812 muscle cell migration; GO:0051128 regulation of cellular component organization; GO:0044089 positive regulation of cellular component biogenesis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0030426 growth cone; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0005885 Arp2/3 protein complex; GO:0031983 vesicle lumen; GO:0005925 focal adhesion; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0030027 lamellipodium; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0005768 endosome; GO:0030055 cell-substrate junction; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0031252 cell leading edge; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0030427 site of polarized growth; GO:0044463 cell projection part; GO:0015629 actin cytoskeleton; GO:0005576 extracellular region; GO:0043226 organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0003779 actin binding; GO:0005515 protein binding; GO:0008092 cytoskeletal protein binding; GO:0005200 structural constituent of cytoskeleton; GO:0005198 structural molecule activity; GO:0005488 binding; ","K05754","ARPC5; actin related protein 2/3 complex, subunit 5","hsa05100 Bacterial invasion of epithelial cells - Homo sapiens (human); hsa05132 Salmonella infection - Homo sapiens (human); hsa04666 Fc gamma R-mediated phagocytosis - Homo sapiens (human); hsa04144 Endocytosis - Homo sapiens (human); hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human); hsa05131 Shigellosis - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); "]
["O15533","Tapasin OS=Homo sapiens OX=9606 GN=TAPBP","TAPBP",47.625,4.7125,4.7,2,2,2,0.846,1,0.829,1.168,1.049,1.109,1.243,0.0302,"plasma membrane\r","GO:0044085 cellular component biogenesis; GO:1990668 vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane; GO:0016043 cellular component organization; GO:0090174 organelle membrane fusion; GO:0065008 regulation of biological quality; GO:0006518 peptide metabolic process; GO:0050822 peptide stabilization; GO:0060255 regulation of macromolecule metabolic process; GO:0048193 Golgi vesicle transport; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0051234 establishment of localization; GO:0019883 antigen processing and presentation of endogenous antigen; GO:0008152 metabolic process; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I; GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I; GO:0034641 cellular nitrogen compound metabolic process; GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; GO:0044801 single-organism membrane fusion; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0010468 regulation of gene expression; GO:0071822 protein complex subunit organization; GO:0050823 peptide antigen stabilization; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:0016192 vesicle-mediated transport; GO:0048002 antigen processing and presentation of peptide antigen; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:0044802 single-organism membrane organization; GO:0061025 membrane fusion; GO:0016050 vesicle organization; GO:0002376 immune system process; GO:0048284 organelle fusion; GO:0043603 cellular amide metabolic process; GO:0061635 regulation of protein complex stability; GO:0043933 macromolecular complex subunit organization; GO:0006810 transport; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0055085 transmembrane transport; GO:1902589 single-organism organelle organization; GO:0019882 antigen processing and presentation; GO:0050789 regulation of biological process; GO:0006890 retrograde vesicle-mediated transport, Golgi to ER; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0006906 vesicle fusion; GO:0019222 regulation of metabolic process; GO:0002483 antigen processing and presentation of endogenous peptide antigen; GO:0070271 protein complex biogenesis; GO:0006955 immune response; GO:0051179 localization; GO:1901564 organonitrogen compound metabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0030670 phagocytic vesicle membrane; GO:0098805 whole membrane; GO:0031227 intrinsic component of endoplasmic reticulum membrane; GO:0044431 Golgi apparatus part; GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane; GO:0030139 endocytic vesicle; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0042824 MHC class I peptide loading complex; GO:0098552 side of membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0030666 endocytic vesicle membrane; GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0045335 phagocytic vesicle; GO:0016021 integral component of membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044432 endoplasmic reticulum part; GO:0098553 lumenal side of endoplasmic reticulum membrane; GO:0005793 endoplasmic reticulum-Golgi intermediate compartment; GO:0043234 protein complex; GO:0030176 integral component of endoplasmic reticulum membrane; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:0022804 active transmembrane transporter activity; GO:0046978 TAP1 binding; GO:0046977 TAP binding; GO:0005102 receptor binding; GO:0015399 primary active transmembrane transporter activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0033218 amide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0042288 MHC class I protein binding; GO:0046979 TAP2 binding; GO:0003823 antigen binding; GO:0016887 ATPase activity; GO:0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity; GO:0016462 pyrophosphatase activity; GO:0042626 ATPase activity, coupled to transmembrane movement of substances; GO:0042277 peptide binding; GO:0003824 catalytic activity; GO:0043492 ATPase activity, coupled to movement of substances; GO:0005488 binding; GO:0042623 ATPase activity, coupled; GO:0042287 MHC protein binding; GO:0015433 peptide antigen-transporting ATPase activity; GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; GO:0015440 peptide-transporting ATPase activity; GO:0042605 peptide antigen binding; GO:0051082 unfolded protein binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; ","K08058","TAPBP; TAP binding protein (tapasin)","hsa04612 Antigen processing and presentation - Homo sapiens (human); ","IPR007110; IPR013783; IPR003597; ","Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin C1-set; \r"]
["O15540","Fatty acid-binding protein, brain OS=Homo sapiens OX=9606 GN=FABP7","FABP7",14.889,22.621,15.9,2,5,2,1.346,1.329,1.303,0.633,0.727,0.71,0.52,1.18E-4,"cytoplasm\r","GO:0046486 glycerolipid metabolic process; GO:0007420 brain development; GO:0048869 cellular developmental process; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0050877 neurological system process; GO:0051234 establishment of localization; GO:0008285 negative regulation of cell proliferation; GO:0061351 neural precursor cell proliferation; GO:0009605 response to external stimulus; GO:0046461 neutral lipid catabolic process; GO:0008152 metabolic process; GO:0032102 negative regulation of response to external stimulus; GO:0006639 acylglycerol metabolic process; GO:0060322 head development; GO:0006629 lipid metabolic process; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0044763 single-organism cellular process; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:0050673 epithelial cell proliferation; GO:1901575 organic substance catabolic process; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0007417 central nervous system development; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:0021846 cell proliferation in forebrain; GO:0048856 anatomical structure development; GO:0046503 glycerolipid catabolic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0042127 regulation of cell proliferation; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:0046464 acylglycerol catabolic process; GO:0071704 organic substance metabolic process; GO:0001964 startle response; GO:0030154 cell differentiation; GO:0044248 cellular catabolic process; GO:0030900 forebrain development; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0019433 triglyceride catabolic process; GO:0006638 neutral lipid metabolic process; GO:0016042 lipid catabolic process; GO:0003008 system process; GO:0048731 system development; GO:0044712 single-organism catabolic process; GO:0008283 cell proliferation; GO:0032101 regulation of response to external stimulus; GO:0048585 negative regulation of response to stimulus; GO:0044238 primary metabolic process; GO:0006641 triglyceride metabolic process; GO:0044767 single-organism developmental process; GO:0060134 prepulse inhibition; GO:0044242 cellular lipid catabolic process; GO:0051179 localization; GO:0009056 catabolic process; GO:0050905 neuromuscular process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0043025 neuronal cell body; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005911 cell-cell junction; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0036477 somatodendritic compartment; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0044297 cell body; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0008289 lipid binding; GO:0005488 binding; GO:0005215 transporter activity; ","K08756","FABP7; fatty acid-binding protein 7, brain","hsa03320 PPAR signaling pathway - Homo sapiens (human); ","IPR000463; IPR000566; IPR012674; IPR011038; ","Cytosolic fatty-acid binding; Lipocalin/cytosolic fatty-acid binding domain; Calycin; Calycin-like; \r"]
["O43143","Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15","DHX15",90.932,46.57,17.9,14,17,14,0.966,0.957,0.925,1.06,1.018,1.058,1.101,0.00666,"nucleus\r","GO:0006725 cellular aromatic compound metabolic process; GO:0043279 response to alkaloid; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0008152 metabolic process; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0009719 response to endogenous stimulus; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0006396 RNA processing; GO:0009636 response to toxic substance; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:0010243 response to organonitrogen compound; GO:0042221 response to chemical; GO:0090304 nucleic acid metabolic process; GO:1901698 response to nitrogen compound; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0016071 mRNA metabolic process; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005681 spliceosomal complex; GO:0005730 nucleolus; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0005622 intracellular; GO:0044464 cell part; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0005689 U12-type spliceosomal complex; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0008026 ATP-dependent helicase activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0016887 ATPase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0004004 ATP-dependent RNA helicase activity; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003723 RNA binding; GO:0005524 ATP binding; GO:0070035 purine NTP-dependent helicase activity; GO:0004386 helicase activity; GO:0003725 double-stranded RNA binding; GO:0008186 RNA-dependent ATPase activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003724 RNA helicase activity; GO:0042623 ATPase activity, coupled; GO:0003676 nucleic acid binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; ","K12820","DHX15; pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15/PRP43 [EC:3.6.4.13]","hsa03040 Spliceosome - Homo sapiens (human); ","IPR007502; IPR011545; IPR011709; IPR027417; IPR014001; IPR001650; ","\"Helicase-associated domain; DEAD/DEAH box helicase domain; Domain of unknown function DUF1605; P-loop containing nucleoside triphosphate hydrolase; Helicase superfamily 1/2, ATP-binding domain; Helicase, C-terminal; \"\r"]
["O43148","mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT","RNMT",54.843,8.8548,8.2,4,6,4,0.948,1.027,0.979,1.089,0.945,1.023,1.035,0.521,"nucleus\r","GO:0006725 cellular aromatic compound metabolic process; GO:0097659 nucleic acid-templated transcription; GO:0009058 biosynthetic process; GO:0009452 7-methylguanosine RNA capping; GO:0009451 RNA modification; GO:0044237 cellular metabolic process; GO:0032259 methylation; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006396 RNA processing; GO:0036260 RNA capping; GO:0018130 heterocycle biosynthetic process; GO:0006370 7-methylguanosine mRNA capping; GO:0036265 RNA (guanine-N7)-methylation; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0043414 macromolecule methylation; GO:0006366 transcription from RNA polymerase II promoter; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0001510 RNA methylation; GO:0043412 macromolecule modification; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0043235 receptor complex; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044452 nucleolar part; GO:0044424 intracellular part; GO:0005730 nucleolus; GO:0034518 RNA cap binding complex; GO:0005623 cell; GO:0001650 fibrillar center; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0005845 mRNA cap binding complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0008757 S-adenosylmethionine-dependent methyltransferase activity; GO:0003723 RNA binding; GO:0008168 methyltransferase activity; GO:0008173 RNA methyltransferase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0016741 transferase activity, transferring one-carbon groups; GO:0008174 mRNA methyltransferase activity; GO:0005515 protein binding; GO:0004482 mRNA (guanine-N7-)-methyltransferase activity; GO:0008170 N-methyltransferase activity; GO:0016740 transferase activity; ","K00565","RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]","hsa03015 mRNA surveillance pathway - Homo sapiens (human); ","IPR029063; IPR004971; ","S-adenosyl-L-methionine-dependent methyltransferase; mRNA (guanine-N(7))-methyltransferase domain; \r"]
["O43149","Zinc finger ZZ-type and EF-hand domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ZZEF1","ZZEF1",331.07,12.194,1.7,5,5,5,1.126,1.072,0.922,0.806,0.921,1.163,0.926,0.529,"plasma membrane\r",null,null,"GO:0046914 transition metal ion binding; GO:0005488 binding; GO:0043167 ion binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005509 calcium ion binding; GO:0008270 zinc ion binding; ",{"$nulls":3},"IPR000859; IPR004939; IPR002048; IPR011992; IPR000433; IPR008979; ","\"CUB domain; APC10/DOC domain; EF-hand domain; EF-hand domain pair; Zinc finger, ZZ-type; Galactose-binding domain-like; \"\r"]
["O43169","Cytochrome b5 type B OS=Homo sapiens OX=9606 GN=CYB5B","CYB5B",16.332,24.552,19.2,3,4,3,1.036,0.952,0.92,0.998,1.151,1.017,1.089,0.213,"peroxisome\r","GO:0071466 cellular response to xenobiotic stimulus; GO:0051716 cellular response to stimulus; GO:0008152 metabolic process; GO:0042221 response to chemical; GO:0006805 xenobiotic metabolic process; GO:0009410 response to xenobiotic stimulus; GO:0055114 oxidation-reduction process; GO:0044710 single-organism metabolic process; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0009987 cellular process; GO:0070887 cellular response to chemical stimulus; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0019867 outer membrane; GO:0044429 mitochondrial part; GO:0098588 bounding membrane of organelle; GO:0031090 organelle membrane; GO:0005741 mitochondrial outer membrane; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005740 mitochondrial envelope; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0031975 envelope; GO:0098805 whole membrane; GO:0031968 organelle outer membrane; GO:0043227 membrane-bounded organelle; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0020037 heme binding; GO:0005488 binding; GO:0043167 ion binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0046906 tetrapyrrole binding; ",{"$nulls":3},"IPR023271; IPR001199; ","Aquaporin-like; Cytochrome b5-like heme/steroid binding domain; \r"]
["O43172","U4/U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4","PRPF4",58.449,7.762,6.5,3,3,3,1.241,0.919,1.064,0.979,0.837,0.98,0.867,0.246,"nucleus\r","GO:0006396 RNA processing; GO:0006725 cellular aromatic compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0008152 metabolic process; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0090304 nucleic acid metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0008380 RNA splicing; GO:0016071 mRNA metabolic process; GO:0009987 cellular process; ","GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0046540 U4/U6 x U5 tri-snRNP complex; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005681 spliceosomal complex; GO:0016604 nuclear body; GO:0005623 cell; GO:0015030 Cajal body; GO:0044422 organelle part; GO:0097525 spliceosomal snRNP complex; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0097526 spliceosomal tri-snRNP complex; GO:0043226 organelle; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0044464 cell part; GO:0005622 intracellular; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0030532 small nuclear ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0071001 U4/U6 snRNP; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0017070 U6 snRNA binding; GO:0005488 binding; GO:0030621 U4 snRNA binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0017069 snRNA binding; ","K12662","PRPF4; U4/U6 small nuclear ribonucleoprotein PRP4","hsa03040 Spliceosome - Homo sapiens (human); ","IPR017986; IPR015943; IPR014906; ","WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain; Pre-mRNA processing factor 4 (PRP4)-like; \r"]
["O43175","D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH","PHGDH",56.65,136.5,39.2,18,36,18,1.005,1.028,1.03,0.975,0.983,0.957,0.952,0.0114,"cytoplasm\r","GO:0016053 organic acid biosynthetic process; GO:0043009 chordate embryonic development; GO:0007420 brain development; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0006544 glycine metabolic process; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:1901607 alpha-amino acid biosynthetic process; GO:0032787 monocarboxylic acid metabolic process; GO:0060322 head development; GO:0019694 alkanesulfonate metabolic process; GO:0009790 embryo development; GO:0006790 sulfur compound metabolic process; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0035295 tube development; GO:0060429 epithelium development; GO:0010468 regulation of gene expression; GO:0009888 tissue development; GO:0021510 spinal cord development; GO:0048699 generation of neurons; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0032501 multicellular organismal process; GO:0019530 taurine metabolic process; GO:0048513 animal organ development; GO:0046394 carboxylic acid biosynthetic process; GO:0042063 gliogenesis; GO:0050789 regulation of biological process; GO:0009069 serine family amino acid metabolic process; GO:0030030 cell projection organization; GO:0006566 threonine metabolic process; GO:0007417 central nervous system development; GO:0044710 single-organism metabolic process; GO:0006563 L-serine metabolic process; GO:0021782 glial cell development; GO:0019222 regulation of metabolic process; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:0043436 oxoacid metabolic process; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0060255 regulation of macromolecule metabolic process; GO:0070314 G1 to G0 transition; GO:0009066 aspartate family amino acid metabolic process; GO:0006541 glutamine metabolic process; GO:0021915 neural tube development; GO:1901566 organonitrogen compound biosynthetic process; GO:0006564 L-serine biosynthetic process; GO:0048468 cell development; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0009448 gamma-aminobutyric acid metabolic process; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0009070 serine family amino acid biosynthetic process; GO:0009064 glutamine family amino acid metabolic process; GO:0008652 cellular amino acid biosynthetic process; GO:0044711 single-organism biosynthetic process; GO:0048731 system development; GO:0009792 embryo development ending in birth or egg hatching; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:1901605 alpha-amino acid metabolic process; GO:0031175 neuron projection development; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0010001 glial cell differentiation; GO:0030182 neuron differentiation; GO:0044767 single-organism developmental process; GO:0019752 carboxylic acid metabolic process; GO:0044283 small molecule biosynthetic process; GO:0022402 cell cycle process; GO:0007049 cell cycle; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043209 myelin sheath; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0016614 oxidoreductase activity, acting on CH-OH group of donors; GO:0009055 electron carrier activity; GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; GO:1901265 nucleoside phosphate binding; GO:0051287 NAD binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0004617 phosphoglycerate dehydrogenase activity; GO:0000166 nucleotide binding; GO:0048037 cofactor binding; GO:0036094 small molecule binding; GO:0050662 coenzyme binding; GO:0016491 oxidoreductase activity; ","K00058","serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00260 Glycine, serine and threonine metabolism - Homo sapiens (human); hsa01230 Biosynthesis of amino acids - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); ","IPR006139; IPR006140; IPR029009; IPR016040; ","\"D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain; Allosteric substrate binding domain; NAD(P)-binding domain; \"\r"]
["O43181","NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS4","NDUFS4",20.108,25.586,25.7,4,10,4,1.05,1.131,1.016,0.927,0.871,0.976,0.868,0.036,"mitochondria\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0007420 brain development; GO:0009117 nucleotide metabolic process; GO:0046683 response to organophosphorus; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0048145 regulation of fibroblast proliferation; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0007154 cell communication; GO:0048146 positive regulation of fibroblast proliferation; GO:0006091 generation of precursor metabolites and energy; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0006753 nucleoside phosphate metabolic process; GO:0019933 cAMP-mediated signaling; GO:0007005 mitochondrion organization; GO:0009719 response to endogenous stimulus; GO:0019693 ribose phosphate metabolic process; GO:0060322 head development; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0014070 response to organic cyclic compound; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0071822 protein complex subunit organization; GO:0010257 NADH dehydrogenase complex assembly; GO:0080090 regulation of primary metabolic process; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0006119 oxidative phosphorylation; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0019932 second-messenger-mediated signaling; GO:0006120 mitochondrial electron transport, NADH to ubiquinone; GO:0023052 signaling; GO:0031323 regulation of cellular metabolic process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0032501 multicellular organismal process; GO:0010243 response to organonitrogen compound; GO:0048513 animal organ development; GO:0042221 response to chemical; GO:0097031 mitochondrial respiratory chain complex I biogenesis; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0051591 response to cAMP; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0007417 central nervous system development; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:1901698 response to nitrogen compound; GO:0022900 electron transport chain; GO:0019222 regulation of metabolic process; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0070271 protein complex biogenesis; GO:0048856 anatomical structure development; GO:0033108 mitochondrial respiratory chain complex assembly; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0016310 phosphorylation; GO:0042127 regulation of cell proliferation; GO:0006725 cellular aromatic compound metabolic process; GO:0042773 ATP synthesis coupled electron transport; GO:0060255 regulation of macromolecule metabolic process; GO:0009259 ribonucleotide metabolic process; GO:0031399 regulation of protein modification process; GO:1901700 response to oxygen-containing compound; GO:0022904 respiratory electron transport chain; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0032981 mitochondrial respiratory chain complex I assembly; GO:0046483 heterocycle metabolic process; GO:0072593 reactive oxygen species metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0014074 response to purine-containing compound; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009119 ribonucleoside metabolic process; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0043623 cellular protein complex assembly; GO:0019935 cyclic-nucleotide-mediated signaling; GO:0046034 ATP metabolic process; GO:0034622 cellular macromolecular complex assembly; GO:0035556 intracellular signal transduction; GO:0048731 system development; GO:0001932 regulation of protein phosphorylation; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0045333 cellular respiration; GO:0006163 purine nucleotide metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0046128 purine ribonucleoside metabolic process; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:0008284 positive regulation of cell proliferation; GO:0071840 cellular component organization or biogenesis; GO:1901564 organonitrogen compound metabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0045271 respiratory chain complex I; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0098798 mitochondrial protein complex; GO:0005747 mitochondrial respiratory chain complex I; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:1902494 catalytic complex; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0098803 respiratory chain complex; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005739 mitochondrion; GO:0005746 mitochondrial respiratory chain; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0030964 NADH dehydrogenase complex; GO:0031975 envelope; GO:1990204 oxidoreductase complex; GO:0043234 protein complex; GO:0031966 mitochondrial membrane; GO:0070469 respiratory chain; GO:0044444 cytoplasmic part; ","GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:0003954 NADH dehydrogenase activity; GO:0003824 catalytic activity; GO:0050136 NADH dehydrogenase (quinone) activity; GO:0008137 NADH dehydrogenase (ubiquinone) activity; GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; GO:0016491 oxidoreductase activity; ","K03937","NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4","hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); "]
["O43237","Cytoplasmic dynein 1 light intermediate chain 2 OS=Homo sapiens OX=9606 GN=DYNC1LI2","DYNC1LI2",54.099,15.124,11.6,5,6,5,0.838,1.043,0.844,1.111,1.07,1.095,1.202,0.121,"cytoplasm\r","GO:0051640 organelle localization; GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0048193 Golgi vesicle transport; GO:0044699 single-organism process; GO:0051234 establishment of localization; GO:0051649 establishment of localization in cell; GO:0007010 cytoskeleton organization; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0009987 cellular process; GO:0061842 microtubule organizing center localization; GO:0048002 antigen processing and presentation of peptide antigen; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0051642 centrosome localization; GO:0002376 immune system process; GO:0007017 microtubule-based process; GO:0002495 antigen processing and presentation of peptide antigen via MHC class II; GO:0051641 cellular localization; GO:0006810 transport; GO:0000226 microtubule cytoskeleton organization; GO:0007018 microtubule-based movement; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0019882 antigen processing and presentation; GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; GO:0006996 organelle organization; GO:0006928 movement of cell or subcellular component; GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II; GO:0051179 localization; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0099513 polymeric cytoskeletal fiber; GO:0005874 microtubule; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0099512 supramolecular fiber; GO:0005875 microtubule associated complex; GO:0030286 dynein complex; GO:0005829 cytosol; GO:0005868 cytoplasmic dynein complex; GO:0005623 cell; GO:0099080 supramolecular complex; GO:0044422 organelle part; GO:0099081 supramolecular polymer; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0043226 organelle; GO:0005815 microtubule organizing center; GO:1902494 catalytic complex; GO:0015630 microtubule cytoskeleton; GO:0005813 centrosome; GO:0005622 intracellular; GO:0044464 cell part; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0005524 ATP binding; GO:0003774 motor activity; GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0003777 microtubule motor activity; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0045504 dynein heavy chain binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K10416","DYNC1LI; dynein light intermediate chain 1, cytosolic","hsa05132 Salmonella infection - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); hsa04962 Vasopressin-regulated water reabsorption - Homo sapiens (human); ","IPR027417; ","P-loop containing nucleoside triphosphate hydrolase; \r"]
["O43242","26S proteasome non-ATPase regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PSMD3","PSMD3",60.977,92.557,34.5,19,31,19,0.954,0.936,0.966,1.047,1.063,1.033,1.1,1.48E-3,"cytoplasm\r","GO:0044700 single organism signaling; GO:0010608 posttranscriptional regulation of gene expression; GO:0051443 positive regulation of ubiquitin-protein transferase activity; GO:0031347 regulation of defense response; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:1903364 positive regulation of cellular protein catabolic process; GO:0008152 metabolic process; GO:0044093 positive regulation of molecular function; GO:0090263 positive regulation of canonical Wnt signaling pathway; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0016055 Wnt signaling pathway; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0006521 regulation of cellular amino acid metabolic process; GO:0080090 regulation of primary metabolic process; GO:0010972 negative regulation of G2/M transition of mitotic cell cycle; GO:0044763 single-organism cellular process; GO:0060828 regulation of canonical Wnt signaling pathway; GO:0043086 negative regulation of catalytic activity; GO:0033209 tumor necrosis factor-mediated signaling pathway; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0000165 MAPK cascade; GO:1901575 organic substance catabolic process; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0007267 cell-cell signaling; GO:0002223 stimulatory C-type lectin receptor signaling pathway; GO:0030163 protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0060071 Wnt signaling pathway, planar cell polarity pathway; GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0016310 phosphorylation; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0043487 regulation of RNA stability; GO:0000209 protein polyubiquitination; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0009889 regulation of biosynthetic process; GO:0009896 positive regulation of catabolic process; GO:0043620 regulation of DNA-templated transcription in response to stress; GO:0070482 response to oxygen levels; GO:0044248 cellular catabolic process; GO:0042176 regulation of protein catabolic process; GO:0038093 Fc receptor signaling pathway; GO:0050778 positive regulation of immune response; GO:0023014 signal transduction by protein phosphorylation; GO:0006950 response to stress; GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; GO:0016567 protein ubiquitination; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0002263 cell activation involved in immune response; GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress; GO:1903321 negative regulation of protein modification by small protein conjugation or removal; GO:0045055 regulated exocytosis; GO:0031398 positive regulation of protein ubiquitination; GO:0032446 protein modification by small protein conjugation; GO:0031325 positive regulation of cellular metabolic process; GO:0030177 positive regulation of Wnt signaling pathway; GO:1904668 positive regulation of ubiquitin protein ligase activity; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0006955 immune response; GO:0043412 macromolecule modification; GO:0070646 protein modification by small protein removal; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0031331 positive regulation of cellular catabolic process; GO:0044699 single-organism process; GO:0031400 negative regulation of protein modification process; GO:0006796 phosphate-containing compound metabolic process; GO:0031396 regulation of protein ubiquitination; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0045930 negative regulation of mitotic cell cycle; GO:0009893 positive regulation of metabolic process; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0034612 response to tumor necrosis factor; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0051726 regulation of cell cycle; GO:0034097 response to cytokine; GO:0031326 regulation of cellular biosynthetic process; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0198738 cell-cell signaling by wnt; GO:0010565 regulation of cellular ketone metabolic process; GO:0032940 secretion by cell; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0036211 protein modification process; GO:0090175 regulation of establishment of planar polarity; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0045786 negative regulation of cell cycle; GO:0044257 cellular protein catabolic process; GO:1901988 negative regulation of cell cycle phase transition; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0010498 proteasomal protein catabolic process; GO:0071704 organic substance metabolic process; GO:0045862 positive regulation of proteolysis; GO:2000027 regulation of organ morphogenesis; GO:0006468 protein phosphorylation; GO:0023056 positive regulation of signaling; GO:0001666 response to hypoxia; GO:0002757 immune response-activating signal transduction; GO:0010647 positive regulation of cell communication; GO:0071453 cellular response to oxygen levels; GO:0019221 cytokine-mediated signaling pathway; GO:0031397 negative regulation of protein ubiquitination; GO:0006355 regulation of transcription, DNA-templated; GO:0035556 intracellular signal transduction; GO:0019941 modification-dependent protein catabolic process; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia; GO:1902749 regulation of cell cycle G2/M phase transition; GO:0043488 regulation of mRNA stability; GO:0043085 positive regulation of catalytic activity; GO:0002366 leukocyte activation involved in immune response; GO:0019882 antigen processing and presentation; GO:0042119 neutrophil activation; GO:0050852 T cell receptor signaling pathway; GO:0002684 positive regulation of immune system process; GO:0038095 Fc-epsilon receptor signaling pathway; GO:0051248 negative regulation of protein metabolic process; GO:0022402 cell cycle process; GO:1902750 negative regulation of cell cycle G2/M phase transition; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0045321 leukocyte activation; GO:0002220 innate immune response activating cell surface receptor signaling pathway; GO:0007166 cell surface receptor signaling pathway; GO:0071345 cellular response to cytokine stimulus; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0051347 positive regulation of transferase activity; GO:1903362 regulation of cellular protein catabolic process; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0002443 leukocyte mediated immunity; GO:0002758 innate immune response-activating signal transduction; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0031323 regulation of cellular metabolic process; GO:2000058 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0010948 negative regulation of cell cycle process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0002682 regulation of immune system process; GO:0031145 anaphase-promoting complex-dependent catabolic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0007346 regulation of mitotic cell cycle; GO:0002283 neutrophil activation involved in immune response; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:0051239 regulation of multicellular organismal process; GO:0031349 positive regulation of defense response; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:1901987 regulation of cell cycle phase transition; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0010389 regulation of G2/M transition of mitotic cell cycle; GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; GO:0009966 regulation of signal transduction; GO:0038061 NIK/NF-kappaB signaling; GO:0071456 cellular response to hypoxia; GO:0002253 activation of immune response; GO:0016192 vesicle-mediated transport; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1904666 regulation of ubiquitin protein ligase activity; GO:0055085 transmembrane transport; GO:0051247 positive regulation of protein metabolic process; GO:0051438 regulation of ubiquitin-protein transferase activity; GO:0030111 regulation of Wnt signaling pathway; GO:0006793 phosphorus metabolic process; GO:0001775 cell activation; GO:0036293 response to decreased oxygen levels; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process; GO:0006887 exocytosis; GO:0051444 negative regulation of ubiquitin-protein transferase activity; GO:0090090 negative regulation of canonical Wnt signaling pathway; GO:0051234 establishment of localization; GO:0035567 non-canonical Wnt signaling pathway; GO:1905330 regulation of morphogenesis of an epithelium; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:1901991 negative regulation of mitotic cell cycle phase transition; GO:0045088 regulation of innate immune response; GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I; GO:0070887 cellular response to chemical stimulus; GO:0002274 myeloid leukocyte activation; GO:0050851 antigen receptor-mediated signaling pathway; GO:0010468 regulation of gene expression; GO:0030178 negative regulation of Wnt signaling pathway; GO:0048002 antigen processing and presentation of peptide antigen; GO:0002446 neutrophil mediated immunity; GO:0048522 positive regulation of cellular process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0051348 negative regulation of transferase activity; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0019222 regulation of metabolic process; GO:0043299 leukocyte degranulation; GO:2000026 regulation of multicellular organismal development; GO:0002218 activation of innate immune response; GO:1904667 negative regulation of ubiquitin protein ligase activity; GO:0002252 immune effector process; GO:0071356 cellular response to tumor necrosis factor; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0016579 protein deubiquitination; GO:1903322 positive regulation of protein modification by small protein conjugation or removal; GO:0006508 proteolysis; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:0033238 regulation of cellular amine metabolic process; GO:0043632 modification-dependent macromolecule catabolic process; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0045089 positive regulation of innate immune response; GO:0031401 positive regulation of protein modification process; GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0051246 regulation of protein metabolic process; GO:0009057 macromolecule catabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0009967 positive regulation of signal transduction; GO:0045732 positive regulation of protein catabolic process; GO:0036294 cellular response to decreased oxygen levels; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0034774 secretory granule lumen; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005838 proteasome regulatory particle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:1905369 endopeptidase complex; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:1902494 catalytic complex; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0022624 proteasome accessory complex; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:1905368 peptidase complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0008541 proteasome regulatory particle, lid subcomplex; GO:0000502 proteasome complex; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0030234 enzyme regulator activity; GO:0098772 molecular function regulator; GO:0005488 binding; ","K03033","PSMD3; 26S proteasome regulatory subunit N3","hsa03050 Proteasome - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); ","IPR011991; IPR000717; IPR011990; IPR013586; ","\"Winged helix-turn-helix DNA-binding domain; Proteasome component (PCI) domain; Tetratricopeptide-like helical domain; 26S proteasome regulatory subunit, C-terminal; \"\r"]
["O43251","RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2","RBFOX2",41.373,12.788,6.4,2,3,2,0.939,1.06,1.068,1.089,0.912,0.946,0.961,0.579,"nucleus\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0000381 regulation of alternative mRNA splicing, via spliceosome; GO:0007166 cell surface receptor signaling pathway; GO:0007420 brain development; GO:0032989 cellular component morphogenesis; GO:0044237 cellular metabolic process; GO:0050877 neurological system process; GO:0021932 hindbrain radial glia guided cell migration; GO:0008152 metabolic process; GO:0030522 intracellular receptor signaling pathway; GO:0048545 response to steroid hormone; GO:0009719 response to endogenous stimulus; GO:0070848 response to growth factor; GO:0043170 macromolecule metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0030518 intracellular steroid hormone receptor signaling pathway; GO:0006396 RNA processing; GO:0007399 nervous system development; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0048812 neuron projection morphogenesis; GO:0050684 regulation of mRNA processing; GO:0048870 cell motility; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0071396 cellular response to lipid; GO:0000902 cell morphogenesis; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0045646 regulation of erythrocyte differentiation; GO:0007417 central nervous system development; GO:0044260 cellular macromolecule metabolic process; GO:0002682 regulation of immune system process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0016071 mRNA metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0042127 regulation of cell proliferation; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0032844 regulation of homeostatic process; GO:0051239 regulation of multicellular organismal process; GO:1903706 regulation of hemopoiesis; GO:0045892 negative regulation of transcription, DNA-templated; GO:0009653 anatomical structure morphogenesis; GO:0046483 heterocycle metabolic process; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0071774 response to fibroblast growth factor; GO:0051171 regulation of nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0008380 RNA splicing; GO:0050885 neuromuscular process controlling balance; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0030902 hindbrain development; GO:0048731 system development; GO:0071407 cellular response to organic cyclic compound; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0043484 regulation of RNA splicing; GO:0030182 neuron differentiation; GO:0009890 negative regulation of biosynthetic process; GO:1903311 regulation of mRNA metabolic process; GO:0006928 movement of cell or subcellular component; GO:0051179 localization; GO:0050905 neuromuscular process; GO:0050793 regulation of developmental process; GO:0051674 localization of cell; GO:0045637 regulation of myeloid cell differentiation; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0071363 cellular response to growth factor stimulus; GO:0008543 fibroblast growth factor receptor signaling pathway; GO:0051253 negative regulation of RNA metabolic process; GO:0071383 cellular response to steroid hormone stimulus; GO:0030520 intracellular estrogen receptor signaling pathway; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0032990 cell part morphogenesis; GO:0048858 cell projection morphogenesis; GO:0060322 head development; GO:0048024 regulation of mRNA splicing, via spliceosome; GO:0070887 cellular response to chemical stimulus; GO:0007167 enzyme linked receptor protein signaling pathway; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0090304 nucleic acid metabolic process; GO:0030030 cell projection organization; GO:0032870 cellular response to hormone stimulus; GO:0048813 dendrite morphogenesis; GO:1902679 negative regulation of RNA biosynthetic process; GO:0019222 regulation of metabolic process; GO:0040011 locomotion; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0016477 cell migration; GO:0016043 cellular component organization; GO:0016358 dendrite development; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0071704 organic substance metabolic process; GO:0000904 cell morphogenesis involved in differentiation; GO:0033993 response to lipid; GO:0030154 cell differentiation; GO:0021535 cell migration in hindbrain; GO:0034641 cellular nitrogen compound metabolic process; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0003008 system process; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0031175 neuron projection development; GO:0051252 regulation of RNA metabolic process; GO:0009755 hormone-mediated signaling pathway; GO:0010724 regulation of definitive erythrocyte differentiation; GO:0071495 cellular response to endogenous stimulus; GO:0044767 single-organism developmental process; GO:0021942 radial glia guided migration of Purkinje cell; GO:0044344 cellular response to fibroblast growth factor stimulus; GO:0010467 gene expression; GO:0031327 negative regulation of cellular biosynthetic process; GO:0009725 response to hormone; GO:0043401 steroid hormone mediated signaling pathway; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003729 mRNA binding; GO:0003723 RNA binding; GO:0003714 transcription corepressor activity; GO:1901265 nucleoside phosphate binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0003712 transcription cofactor activity; GO:0000988 transcription factor activity, protein binding; GO:0008134 transcription factor binding; GO:0036094 small molecule binding; ","K14946",null,null,"IPR034237; IPR025670; IPR000504; IPR012677; ","\"FOX1, RNA recognition motif; Fox-1 C-terminal domain; RNA recognition motif domain; Nucleotide-binding alpha-beta plait domain; \"\r"]
["O43252","Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 OS=Homo sapiens OX=9606 GN=PAPSS1","PAPSS1",70.832,7.1397,4.8,3,3,3,0.873,0.922,0.876,1.048,1.134,1.139,1.243,0.00254,"nucleus\r","GO:0000103 sulfate assimilation; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0009163 nucleoside biosynthetic process; GO:0046129 purine ribonucleoside biosynthetic process; GO:0044237 cellular metabolic process; GO:0044272 sulfur compound biosynthetic process; GO:0006796 phosphate-containing compound metabolic process; GO:0046390 ribose phosphate biosynthetic process; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0034032 purine nucleoside bisphosphate metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0034033 purine nucleoside bisphosphate biosynthetic process; GO:0034036 purine ribonucleoside bisphosphate biosynthetic process; GO:0032502 developmental process; GO:0006790 sulfur compound metabolic process; GO:0018130 heterocycle biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0032501 multicellular organismal process; GO:0042451 purine nucleoside biosynthetic process; GO:0090407 organophosphate biosynthetic process; GO:0044710 single-organism metabolic process; GO:0072522 purine-containing compound biosynthetic process; GO:1901657 glycosyl compound metabolic process; GO:0006164 purine nucleotide biosynthetic process; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:0001501 skeletal system development; GO:1901362 organic cyclic compound biosynthetic process; GO:0043436 oxoacid metabolic process; GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process; GO:0044707 single-multicellular organism process; GO:0016310 phosphorylation; GO:0009165 nucleotide biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0009259 ribonucleotide metabolic process; GO:0050428 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0033866 nucleoside bisphosphate biosynthetic process; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0034030 ribonucleoside bisphosphate biosynthetic process; GO:0009987 cellular process; GO:0009119 ribonucleoside metabolic process; GO:0033865 nucleoside bisphosphate metabolic process; GO:0044711 single-organism biosynthetic process; GO:0048731 system development; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0033875 ribonucleoside bisphosphate metabolic process; GO:0042455 ribonucleoside biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0006163 purine nucleotide metabolic process; GO:0046128 purine ribonucleoside metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0009152 purine ribonucleotide biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0044767 single-organism developmental process; GO:0034035 purine ribonucleoside bisphosphate metabolic process; GO:1901659 glycosyl compound biosynthetic process; GO:0009260 ribonucleotide biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0042802 identical protein binding; GO:0016301 kinase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0004781 sulfate adenylyltransferase (ATP) activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0004779 sulfate adenylyltransferase activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0070566 adenylyltransferase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016779 nucleotidyltransferase activity; GO:0004020 adenylylsulfate kinase activity; GO:0042803 protein homodimerization activity; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K13811","PAPSS; 3'-phosphoadenosine 5'-phosphosulfate synthase [EC:2.7.7.4 2.7.1.25]","hsa00230 Purine metabolism - Homo sapiens (human); hsa00920 Sulfur metabolism - Homo sapiens (human); hsa00450 Selenocompound metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR014729; IPR015947; IPR027417; IPR025980; IPR024951; IPR002650; ","Rossmann-like alpha/beta/alpha sandwich fold; PUA-like domain; P-loop containing nucleoside triphosphate hydrolase; ATP-sulfurylase PUA-like domain; Sulphate adenylyltransferase catalytic domain; Sulphate adenylyltransferase; \r"]
["O43264","Centromere/kinetochore protein zw10 homolog OS=Homo sapiens OX=9606 GN=ZW10","ZW10",88.828,23.031,7.6,5,6,5,0.927,0.944,1.058,1.05,0.993,1.032,1.05,0.324,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0000132 establishment of mitotic spindle orientation; GO:0010256 endomembrane system organization; GO:0022414 reproductive process; GO:0051129 negative regulation of cellular component organization; GO:0007067 mitotic nuclear division; GO:0044699 single-organism process; GO:0030071 regulation of mitotic metaphase/anaphase transition; GO:0010564 regulation of cell cycle process; GO:1902100 negative regulation of metaphase/anaphase transition of cell cycle; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0033048 negative regulation of mitotic sister chromatid segregation; GO:0051783 regulation of nuclear division; GO:0045930 negative regulation of mitotic cell cycle; GO:0050000 chromosome localization; GO:0000819 sister chromatid segregation; GO:0031577 spindle checkpoint; GO:0051649 establishment of localization in cell; GO:1901991 negative regulation of mitotic cell cycle phase transition; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0044702 single organism reproductive process; GO:0051784 negative regulation of nuclear division; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0000075 cell cycle checkpoint; GO:0033365 protein localization to organelle; GO:0007096 regulation of exit from mitosis; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0051726 regulation of cell cycle; GO:0000278 mitotic cell cycle; GO:0033045 regulation of sister chromatid segregation; GO:0007059 chromosome segregation; GO:0071822 protein complex subunit organization; GO:0007094 mitotic spindle assembly checkpoint; GO:1905818 regulation of chromosome separation; GO:0033047 regulation of mitotic sister chromatid segregation; GO:0007088 regulation of mitotic nuclear division; GO:0044763 single-organism cellular process; GO:0051294 establishment of spindle orientation; GO:0034501 protein localization to kinetochore; GO:0045841 negative regulation of mitotic metaphase/anaphase transition; GO:0051985 negative regulation of chromosome segregation; GO:0051321 meiotic cell cycle; GO:0007163 establishment or maintenance of cell polarity; GO:0006810 transport; GO:0010639 negative regulation of organelle organization; GO:1902589 single-organism organelle organization; GO:0000226 microtubule cytoskeleton organization; GO:0010948 negative regulation of cell cycle process; GO:1905819 negative regulation of chromosome separation; GO:0050789 regulation of biological process; GO:0007030 Golgi organization; GO:0051301 cell division; GO:0045839 negative regulation of mitotic nuclear division; GO:0070271 protein complex biogenesis; GO:0000003 reproduction; GO:0034502 protein localization to chromosome; GO:0051640 organelle localization; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0071459 protein localization to chromosome, centromeric region; GO:0007346 regulation of mitotic cell cycle; GO:0045786 negative regulation of cell cycle; GO:1903046 meiotic cell cycle process; GO:1901988 negative regulation of cell cycle phase transition; GO:0051653 spindle localization; GO:0048285 organelle fission; GO:0048193 Golgi vesicle transport; GO:0007080 mitotic metaphase plate congression; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0051310 metaphase plate congression; GO:2000816 negative regulation of mitotic sister chromatid separation; GO:1903047 mitotic cell cycle process; GO:0071174 mitotic spindle checkpoint; GO:1901987 regulation of cell cycle phase transition; GO:0030010 establishment of cell polarity; GO:0007093 mitotic cell cycle checkpoint; GO:0034613 cellular protein localization; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0051293 establishment of spindle localization; GO:0051983 regulation of chromosome segregation; GO:0071173 spindle assembly checkpoint; GO:0051303 establishment of chromosome localization; GO:0016192 vesicle-mediated transport; GO:1902099 regulation of metaphase/anaphase transition of cell cycle; GO:0000070 mitotic sister chromatid segregation; GO:0033043 regulation of organelle organization; GO:0071702 organic substance transport; GO:0051656 establishment of organelle localization; GO:0007017 microtubule-based process; GO:0033044 regulation of chromosome organization; GO:0043933 macromolecular complex subunit organization; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0033046 negative regulation of sister chromatid segregation; GO:0070727 cellular macromolecule localization; GO:2001251 negative regulation of chromosome organization; GO:0010965 regulation of mitotic sister chromatid separation; GO:0051276 chromosome organization; GO:0006890 retrograde vesicle-mediated transport, Golgi to ER; GO:0006996 organelle organization; GO:0098813 nuclear chromosome segregation; GO:0000280 nuclear division; GO:0007126 meiotic nuclear division; GO:0007062 sister chromatid cohesion; GO:0022402 cell cycle process; GO:0040001 establishment of mitotic spindle localization; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0005874 microtubule; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0000777 condensed chromosome kinetochore; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0044427 chromosomal part; GO:0005856 cytoskeleton; GO:0000793 condensed chromosome; GO:0015630 microtubule cytoskeleton; GO:0044425 membrane part; GO:0070939 Dsl1/NZR complex; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0005828 kinetochore microtubule; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0000776 kinetochore; GO:0099023 tethering complex; GO:0043229 intracellular organelle; GO:0000922 spindle pole; GO:0099513 polymeric cytoskeletal fiber; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0000779 condensed chromosome, centromeric region; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005819 spindle; GO:0099081 supramolecular polymer; GO:0005876 spindle microtubule; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0098687 chromosomal region; GO:0005634 nucleus; GO:0044432 endoplasmic reticulum part; GO:0000775 chromosome, centromeric region; GO:1990423 RZZ complex; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003677 DNA binding; GO:0019237 centromeric DNA binding; GO:0003690 double-stranded DNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:1990837 sequence-specific double-stranded DNA binding; GO:0005515 protein binding; GO:0043565 sequence-specific DNA binding; ","K11578"]
["O43278","Kunitz-type protease inhibitor 1 OS=Homo sapiens OX=9606 GN=SPINT1","SPINT1",58.397,18.659,11.7,6,8,6,1.07,1.073,0.865,0.954,1.103,0.947,0.999,0.99,"plasma membrane\r","GO:0052548 regulation of endopeptidase activity; GO:0050794 regulation of cellular process; GO:0010951 negative regulation of endopeptidase activity; GO:0045861 negative regulation of proteolysis; GO:0080090 regulation of primary metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0030162 regulation of proteolysis; GO:0031323 regulation of cellular metabolic process; GO:0043086 negative regulation of catalytic activity; GO:0009892 negative regulation of metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051346 negative regulation of hydrolase activity; GO:0010466 negative regulation of peptidase activity; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0051246 regulation of protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0019222 regulation of metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0052547 regulation of peptidase activity; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:0004867 serine-type endopeptidase inhibitor activity; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0030414 peptidase inhibitor activity; GO:0061134 peptidase regulator activity; GO:0005515 protein binding; GO:0061135 endopeptidase regulator activity; GO:0098772 molecular function regulator; GO:0004857 enzyme inhibitor activity; GO:0004866 endopeptidase inhibitor activity; ","K15619","SPINT1; Kunitz-type protease inhibitor 1","hsa05215 Prostate cancer - Homo sapiens (human); hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human); ","IPR011106; IPR013980; IPR002223; ","\"Seven cysteines, N-terminal; MANSC domain; Pancreatic trypsin inhibitor Kunitz domain; \"\r"]
["O43294","Transforming growth factor beta-1-induced transcript 1 protein OS=Homo sapiens OX=9606 GN=TGFB1I1","TGFB1I1",49.814,32.788,11.1,4,6,4,0.923,0.923,1.041,1.036,1.054,1.023,1.078,0.134,"nucleus\r","GO:0044700 single organism signaling; GO:0010717 regulation of epithelial to mesenchymal transition; GO:0007166 cell surface receptor signaling pathway; GO:0097659 nucleic acid-templated transcription; GO:0009891 positive regulation of biosynthetic process; GO:1903845 negative regulation of cellular response to transforming growth factor beta stimulus; GO:0044237 cellular metabolic process; GO:0008285 negative regulation of cell proliferation; GO:0022610 biological adhesion; GO:0090100 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0008152 metabolic process; GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0051240 positive regulation of multicellular organismal process; GO:0045599 negative regulation of fat cell differentiation; GO:0009408 response to heat; GO:0030522 intracellular receptor signaling pathway; GO:0048545 response to steroid hormone; GO:0007155 cell adhesion; GO:0009719 response to endogenous stimulus; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0016055 Wnt signaling pathway; GO:0009790 embryo development; GO:0048598 embryonic morphogenesis; GO:0030518 intracellular steroid hormone receptor signaling pathway; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044763 single-organism cellular process; GO:0032774 RNA biosynthetic process; GO:0090287 regulation of cellular response to growth factor stimulus; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0071396 cellular response to lipid; GO:1901575 organic substance catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0007267 cell-cell signaling; GO:0030163 protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051094 positive regulation of developmental process; GO:1901362 organic cyclic compound biosynthetic process; GO:0030855 epithelial cell differentiation; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0002009 morphogenesis of an epithelium; GO:0044707 single-multicellular organism process; GO:0042127 regulation of cell proliferation; GO:0009628 response to abiotic stimulus; GO:0044267 cellular protein metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0051239 regulation of multicellular organismal process; GO:0045597 positive regulation of cell differentiation; GO:0009653 anatomical structure morphogenesis; GO:0023057 negative regulation of signaling; GO:0046483 heterocycle metabolic process; GO:0010648 negative regulation of cell communication; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0044248 cellular catabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0016331 morphogenesis of embryonic epithelium; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:0051254 positive regulation of RNA metabolic process; GO:0006950 response to stress; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0071407 cellular response to organic cyclic compound; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0045165 cell fate commitment; GO:0010718 positive regulation of epithelial to mesenchymal transition; GO:0031325 positive regulation of cellular metabolic process; GO:0048584 positive regulation of response to stimulus; GO:0031328 positive regulation of cellular biosynthetic process; GO:0050793 regulation of developmental process; GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway; GO:0051093 negative regulation of developmental process; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0071383 cellular response to steroid hormone stimulus; GO:2001141 regulation of RNA biosynthetic process; GO:0048729 tissue morphogenesis; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0045596 negative regulation of cell differentiation; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0010468 regulation of gene expression; GO:0009888 tissue development; GO:0031326 regulation of cellular biosynthetic process; GO:0030521 androgen receptor signaling pathway; GO:1903846 positive regulation of cellular response to transforming growth factor beta stimulus; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0023052 signaling; GO:0198738 cell-cell signaling by wnt; GO:0016070 RNA metabolic process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0032870 cellular response to hormone stimulus; GO:0019222 regulation of metabolic process; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0017015 regulation of transforming growth factor beta receptor signaling pathway; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0071310 cellular response to organic substance; GO:0050896 response to stimulus; GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0071704 organic substance metabolic process; GO:0033993 response to lipid; GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0030154 cell differentiation; GO:0023056 positive regulation of signaling; GO:0090288 negative regulation of cellular response to growth factor stimulus; GO:0009266 response to temperature stimulus; GO:0006508 proteolysis; GO:0034641 cellular nitrogen compound metabolic process; GO:0010647 positive regulation of cell communication; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0043632 modification-dependent macromolecule catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0019941 modification-dependent protein catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0009755 hormone-mediated signaling pathway; GO:0044249 cellular biosynthetic process; GO:1903844 regulation of cellular response to transforming growth factor beta stimulus; GO:0045598 regulation of fat cell differentiation; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0071495 cellular response to endogenous stimulus; GO:0044767 single-organism developmental process; GO:0009057 macromolecule catabolic process; GO:0006366 transcription from RNA polymerase II promoter; GO:0030579 ubiquitin-dependent SMAD protein catabolic process; GO:0010467 gene expression; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0009967 positive regulation of signal transduction; GO:0009725 response to hormone; GO:0009056 catabolic process; GO:0043401 steroid hormone mediated signaling pathway; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0030054 cell junction; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0070161 anchoring junction; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0005856 cytoskeleton; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0044464 cell part; GO:0016363 nuclear matrix; GO:0005912 adherens junction; GO:0030055 cell-substrate junction; GO:0034399 nuclear periphery; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0005924 cell-substrate adherens junction; GO:0044428 nuclear part; ","GO:0048495 Roundabout binding; GO:0005102 receptor binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0050681 androgen receptor binding; GO:0051427 hormone receptor binding; GO:0003712 transcription cofactor activity; GO:0008270 zinc ion binding; GO:0046914 transition metal ion binding; GO:0005488 binding; GO:0035258 steroid hormone receptor binding; GO:0035257 nuclear hormone receptor binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0003713 transcription coactivator activity; GO:0070411 I-SMAD binding; GO:0046332 SMAD binding; GO:0000988 transcription factor activity, protein binding; ",{"$nulls":3},"IPR001781; ","\"Zinc finger, LIM-type; \"\r"]
["O43301","Heat shock 70 kDa protein 12A OS=Homo sapiens OX=9606 GN=HSPA12A","HSPA12A",74.977,36.142,12.9,7,13,7,1.105,1.207,1.131,0.917,0.791,0.857,0.745,0.00418,"cytoplasm\r",null,"GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; "]
["O43324","Eukaryotic translation elongation factor 1 epsilon-1 OS=Homo sapiens OX=9606 GN=EEF1E1","EEF1E1",19.81,4.9496,16.1,3,3,3,0.918,0.925,0.962,1.078,1.041,1.076,1.139,0.0021,"cytoplasm\r","GO:0010941 regulation of cell death; GO:0006518 peptide metabolic process; GO:0090342 regulation of cell aging; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0008285 negative regulation of cell proliferation; GO:0008152 metabolic process; GO:0010646 regulation of cell communication; GO:0006520 cellular amino acid metabolic process; GO:0006418 tRNA aminoacylation for protein translation; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006412 translation; GO:2000772 regulation of cellular senescence; GO:2001022 positive regulation of response to DNA damage stimulus; GO:0043043 peptide biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0043603 cellular amide metabolic process; GO:0010942 positive regulation of cell death; GO:0016070 RNA metabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0080135 regulation of cellular response to stress; GO:1901798 positive regulation of signal transduction by p53 class mediator; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:2000774 positive regulation of cellular senescence; GO:0006082 organic acid metabolic process; GO:0051094 positive regulation of developmental process; GO:0043436 oxoacid metabolic process; GO:0043068 positive regulation of programmed cell death; GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator; GO:0050794 regulation of cellular process; GO:0042127 regulation of cell proliferation; GO:0006725 cellular aromatic compound metabolic process; GO:2001020 regulation of response to DNA damage stimulus; GO:0043067 regulation of programmed cell death; GO:0044267 cellular protein metabolic process; GO:0043065 positive regulation of apoptotic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0080134 regulation of response to stress; GO:1901566 organonitrogen compound biosynthetic process; GO:0043039 tRNA aminoacylation; GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0023056 positive regulation of signaling; GO:1901796 regulation of signal transduction by p53 class mediator; GO:0034641 cellular nitrogen compound metabolic process; GO:0010647 positive regulation of cell communication; GO:0009059 macromolecule biosynthetic process; GO:0009966 regulation of signal transduction; GO:0090343 positive regulation of cell aging; GO:0009987 cellular process; GO:1902531 regulation of intracellular signal transduction; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0006399 tRNA metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0019752 carboxylic acid metabolic process; GO:0043038 amino acid activation; GO:0010467 gene expression; GO:0009967 positive regulation of signal transduction; GO:0043604 amide biosynthetic process; GO:0048584 positive regulation of response to stimulus; GO:0050793 regulation of developmental process; GO:0034660 ncRNA metabolic process; GO:0042981 regulation of apoptotic process; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0005488 binding; ","K15439",null,null,"IPR004046; IPR010987; IPR012336; ","\"Glutathione S-transferase, C-terminal; Glutathione S-transferase, C-terminal-like; Thioredoxin-like fold; \"\r"]
["O43353","Receptor-interacting serine/threonine-protein kinase 2 OS=Homo sapiens OX=9606 GN=RIPK2","RIPK2",61.194,2.6797,3.1,2,2,2,1.086,1.122,1.102,0.973,0.862,0.88,0.82,0.00664,"cytoplasm\r",{"$cut":{"chars":18510,"head":"GO:0044700 single organism signaling; GO:0002694 regulation of leukocyte activation; GO:0010941 regulation of cell death; GO:0032872 regulation of stress-activated MAPK cascade; GO:0032680 regulation of tumor necrosis factor production; GO:0098542 defense response to other organism; GO:0009891 positive regulation of biosynthetic process; GO:0018212 peptidyl-tyrosine modification; GO:0035872 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; GO:0070555 response to interleukin-1; GO:0031347 regulation of defense response; GO:0044237 cellular metabolic process; GO:0009607 response to biotic stimulus; GO:0042110 T cell activation; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0008152 metabolic process; GO:0032946 positive regulation of mononuclear cell proliferation; GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling; GO:0044093 positive regulation of molecular function; GO:0030522 intracellular receptor signaling pathway; GO:0043370 regulation of CD4-positive, alpha-beta T cell differentiation; GO:0045621 positive regulation of lymphocyte differentiation; GO:0033138 positive regulation of peptidyl-serine phosphorylation; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0080090 regulation of primary metabolic process; GO:0060760 positive regulation of response to cytokine stimulus; GO:0044763 single-organism cellular process; GO:0010506 regulation of autophagy; GO:0071396 cellular response to lipid; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0016241 regulation of macroautophagy; GO:0000165 MAPK cascade; GO:0010243 response to organonitrogen compound; GO:0051092 positive regulation of NF-kappaB transcription factor activity; GO:0080135 regulation of cellular response to stress; GO:0032874 positive regulation of stress-activated MAPK cascade; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0016239 positive regulation of macroautophagy; GO:0060548 negative regulation of cell death; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0016310 phosphorylation; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0045580 regulation of T cell differentiation; GO:0001819 positive regulation of cytokine production; GO:1901700 response to oxygen-containing compound; GO:0048519 negative regulation of biological process; GO:1903706 regulation of hemopoiesis; GO:0050867 positive regulation of cell activation; GO:0009889 regulation of biosynthetic process; GO:0009896 positive regulation of catabolic process; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:1902680 positive regulation of RNA biosynthetic process; GO:2000516 positive regulation of CD4-positive, alpha-beta T cell activation; GO:0050778 positive regulation of immune response; GO:0023014 signal transduction by protein phosphorylation; GO:0006950 response to stress; GO:0045785 positive regulation of cell adhesion; GO:0032648 regulation of interferon-beta production; GO:0032496 response to lipopolysaccharide; GO:0071225 cellular response to muramyl dipeptide; GO:0001961 positive regulation of cytokine-mediated signaling pathway; GO:0032743 positive regulation of interleukin-2 production; GO:0008283 cell proliferation; GO:0032101 regulation of response to external stimulus; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:1903039 positive regulation of leukocyte cell-cell adhesion; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0002696 positive regulation of leukocyte activation; GO:0032727 positive regulation of interferon-alpha production; GO:0031398 positive regulation of protein ubiquitination; GO:0031325 positive regulation of cellular metabolic process; GO:0071219 cellular response to molecule of bacterial origin; GO:0043412 macromolecule modification; GO"}},"GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0005856 cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0005102 receptor binding; GO:0046983 protein dimerization activity; GO:0050700 CARD domain binding; GO:0004713 protein tyrosine kinase activity; GO:0030274 LIM domain binding; GO:0005515 protein binding; GO:0004672 protein kinase activity; GO:0004871 signal transducer activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016301 kinase activity; GO:0042802 identical protein binding; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0032549 ribonucleoside binding; GO:0004715 non-membrane spanning protein tyrosine kinase activity; GO:0097367 carbohydrate derivative binding; GO:0042803 protein homodimerization activity; GO:0004674 protein serine/threonine kinase activity; GO:0019904 protein domain specific binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0036094 small molecule binding; ","K08846","RIPK2; receptor-interacting serine/threonine-protein kinase 2 [EC:2.7.11.1]","hsa05152 Tuberculosis - Homo sapiens (human); hsa04722 Neurotrophin signaling pathway - Homo sapiens (human); hsa05131 Shigellosis - Homo sapiens (human); hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human); ","IPR000719; IPR001245; IPR011029; IPR011009; IPR001315; ","Protein kinase domain; Serine-threonine/tyrosine-protein kinase catalytic domain; Death-like domain; Protein kinase-like domain; CARD domain; \r"]
["O43390","Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR","HNRNPR",70.942,84.13,27,17,30,11,0.955,0.96,0.966,1.005,1.041,0.987,1.053,0.0329,"nucleus\r","GO:0065008 regulation of biological quality; GO:0010608 posttranscriptional regulation of gene expression; GO:0031331 positive regulation of cellular catabolic process; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0006396 RNA processing; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0034249 negative regulation of cellular amide metabolic process; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:1903313 positive regulation of mRNA metabolic process; GO:0007623 circadian rhythm; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0090304 nucleic acid metabolic process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0016071 mRNA metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050779 RNA destabilization; GO:0050794 regulation of cellular process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0017148 negative regulation of translation; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0043487 regulation of RNA stability; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0061014 positive regulation of mRNA catabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0009896 positive regulation of catabolic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0061013 regulation of mRNA catabolic process; GO:0008380 RNA splicing; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0009987 cellular process; GO:0051254 positive regulation of RNA metabolic process; GO:0010629 negative regulation of gene expression; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0009892 negative regulation of metabolic process; GO:0043488 regulation of mRNA stability; GO:0061157 mRNA destabilization; GO:0034248 regulation of cellular amide metabolic process; GO:1903311 regulation of mRNA metabolic process; GO:0009890 negative regulation of biosynthetic process; GO:0051246 regulation of protein metabolic process; GO:0006417 regulation of translation; GO:0048511 rhythmic process; GO:0031325 positive regulation of cellular metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0010467 gene expression; GO:0031327 negative regulation of cellular biosynthetic process; GO:0065007 biological regulation; ","GO:0030425 dendrite; GO:0005783 endoplasmic reticulum; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0030426 growth cone; GO:0044424 intracellular part; GO:0005623 cell; GO:0043679 axon terminus; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0098793 presynapse; GO:0044464 cell part; GO:0005622 intracellular; GO:0043005 neuron projection; GO:0044306 neuron projection terminus; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043233 organelle lumen; GO:0044456 synapse part; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0005681 spliceosomal complex; GO:0030427 site of polarized growth; GO:0044463 cell projection part; GO:0045202 synapse; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0036477 somatodendritic compartment; GO:0005634 nucleus; GO:0071013 catalytic step 2 spliceosome; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003729 mRNA binding; GO:0003723 RNA binding; GO:1901265 nucleoside phosphate binding; GO:0003730 mRNA 3'-UTR binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0036094 small molecule binding; ","K13161",null,null,"IPR000504; IPR012677; ","RNA recognition motif domain; Nucleotide-binding alpha-beta plait domain; \r"]
["O43395","U4/U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3","PRPF3",77.528,7.0552,5.4,4,4,4,0.918,1.004,0.895,1.23,0.991,0.973,1.134,0.218,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0016043 cellular component organization; GO:0022613 ribonucleoprotein complex biogenesis; GO:0022618 ribonucleoprotein complex assembly; GO:0006725 cellular aromatic compound metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0008152 metabolic process; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0071826 ribonucleoprotein complex subunit organization; GO:0046483 heterocycle metabolic process; GO:0022607 cellular component assembly; GO:0006139 nucleobase-containing compound metabolic process; GO:0065003 macromolecular complex assembly; GO:0000375 RNA splicing, via transesterification reactions; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0006396 RNA processing; GO:0034622 cellular macromolecular complex assembly; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0044238 primary metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:0000244 spliceosomal tri-snRNP complex assembly; GO:0090304 nucleic acid metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0016071 mRNA metabolic process; GO:0071840 cellular component organization or biogenesis; GO:0000387 spliceosomal snRNP assembly; ","GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0015030 Cajal body; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0097526 spliceosomal tri-snRNP complex; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0046540 U4/U6 x U5 tri-snRNP complex; GO:0031981 nuclear lumen; GO:0005681 spliceosomal complex; GO:0005829 cytosol; GO:0097525 spliceosomal snRNP complex; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:1990904 ribonucleoprotein complex; GO:0043234 protein complex; GO:0030532 small nuclear ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005515 protein binding; GO:0042802 identical protein binding; GO:0005488 binding; GO:0003676 nucleic acid binding; ","K12843","PRPF3; U4/U6 small nuclear ribonucleoprotein PRP3","hsa03040 Spliceosome - Homo sapiens (human); ","IPR013881; IPR002483; IPR010541; ","Pre-mRNA-splicing factor 3; PWI domain; Domain of unknown function DUF1115; \r"]
["O43396","Thioredoxin-like protein 1 OS=Homo sapiens OX=9606 GN=TXNL1","TXNL1",32.251,110.06,50.9,9,12,9,0.971,0.906,0.91,1.025,1.051,1.055,1.123,0.00842,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0051716 cellular response to stimulus; GO:0065008 regulation of biological quality; GO:0006950 response to stress; GO:0055114 oxidation-reduction process; GO:0009636 response to toxic substance; GO:0045454 cell redox homeostasis; GO:0044763 single-organism cellular process; GO:0019725 cellular homeostasis; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0042592 homeostatic process; GO:0008152 metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:1990748 cellular detoxification; GO:0044710 single-organism metabolic process; GO:0006979 response to oxidative stress; GO:0034599 cellular response to oxidative stress; GO:0098869 cellular oxidant detoxification; GO:0098754 detoxification; GO:0009987 cellular process; GO:0070887 cellular response to chemical stimulus; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0000502 proteasome complex; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:1905369 endopeptidase complex; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:1902494 catalytic complex; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:1905368 peptidase complex; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0015035 protein disulfide oxidoreductase activity; GO:0015036 disulfide oxidoreductase activity; GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:0003824 catalytic activity; GO:0004791 thioredoxin-disulfide reductase activity; GO:0047134 protein-disulfide reductase activity; GO:0016209 antioxidant activity; GO:0016667 oxidoreductase activity, acting on a sulfur group of donors; GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor; GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor; GO:0016491 oxidoreductase activity; ",{"$nulls":3},"IPR012336; IPR013766; IPR008979; IPR010400; ","Thioredoxin-like fold; Thioredoxin domain; Galactose-binding domain-like; PITH domain; \r"]
["O43399","Tumor protein D54 OS=Homo sapiens OX=9606 GN=TPD52L2","TPD52L2",22.237,45.701,30.6,5,9,5,0.996,0.921,0.957,1.016,1.094,1.031,1.093,0.0499,"cyto_nucl\r","GO:0050794 regulation of cellular process; GO:0050789 regulation of biological process; GO:0042127 regulation of cell proliferation; GO:0065007 biological regulation; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0048471 perinuclear region of cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0042802 identical protein binding; GO:0046982 protein heterodimerization activity; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0046983 protein dimerization activity; GO:0003676 nucleic acid binding; GO:0005515 protein binding; "]
["O43405","Cochlin OS=Homo sapiens OX=9606 GN=COCH","COCH",59.482,11.029,4,2,3,2,1.059,1.11,1.01,1.001,0.891,0.95,0.894,0.0603,"extracellular\r","GO:0050794 regulation of cellular process; GO:0065008 regulation of biological quality; GO:0098542 defense response to other organism; GO:0043207 response to external biotic stimulus; GO:0080134 regulation of response to stress; GO:0050896 response to stimulus; GO:0031347 regulation of defense response; GO:0051707 response to other organism; GO:0050877 neurological system process; GO:0009607 response to biotic stimulus; GO:0009605 response to external stimulus; GO:0031349 positive regulation of defense response; GO:0045088 regulation of innate immune response; GO:0008360 regulation of cell shape; GO:0050778 positive regulation of immune response; GO:0009617 response to bacterium; GO:0007600 sensory perception; GO:0003008 system process; GO:0045089 positive regulation of innate immune response; GO:0006950 response to stress; GO:0042742 defense response to bacterium; GO:0032501 multicellular organismal process; GO:0048518 positive regulation of biological process; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0050789 regulation of biological process; GO:0048583 regulation of response to stimulus; GO:0002684 positive regulation of immune system process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0002682 regulation of immune system process; GO:0007605 sensory perception of sound; GO:0006952 defense response; GO:0051128 regulation of cellular component organization; GO:0048584 positive regulation of response to stimulus; GO:0022604 regulation of cell morphogenesis; GO:0050793 regulation of developmental process; GO:0050954 sensory perception of mechanical stimulus; GO:0065007 biological regulation; ","GO:0031012 extracellular matrix; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0005578 proteinaceous extracellular matrix; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:0005518 collagen binding; GO:0005515 protein binding; GO:0005488 binding; GO:0032403 protein complex binding; GO:0044877 macromolecular complex binding; ",{"$nulls":3},"IPR004043; IPR002035; ","\"LCCL domain; von Willebrand factor, type A; \"\r"]
["O43414","ERI1 exoribonuclease 3 OS=Homo sapiens OX=9606 GN=ERI3","ERI3",37.238,22.038,11.3,3,3,3,0.97,1.017,0.952,0.946,1.039,0.955,1,0.996,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0031123 RNA 3'-end processing; GO:0022613 ribonucleoprotein complex biogenesis; GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); GO:0006725 cellular aromatic compound metabolic process; GO:0000467 exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); GO:0000460 maturation of 5.8S rRNA; GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0043628 ncRNA 3'-end processing; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0006364 rRNA processing; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0009987 cellular process; GO:0016072 rRNA metabolic process; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0031125 rRNA 3'-end processing; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0042254 ribosome biogenesis; GO:0044238 primary metabolic process; GO:0016070 RNA metabolic process; GO:0090501 RNA phosphodiester bond hydrolysis; GO:0000469 cleavage involved in rRNA processing; GO:0090304 nucleic acid metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0000459 exonucleolytic trimming involved in rRNA processing; GO:0090305 nucleic acid phosphodiester bond hydrolysis; GO:0034660 ncRNA metabolic process; GO:0071840 cellular component organization or biogenesis; ",null,"GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0004518 nuclease activity; GO:0043167 ion binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0004527 exonuclease activity; GO:0016787 hydrolase activity; ","K18418",null,null,"IPR012337; IPR013520; ","\"Ribonuclease H-like domain; Exonuclease, RNase T/DNA polymerase III; \"\r"]
["O43427","Acidic fibroblast growth factor intracellular-binding protein OS=Homo sapiens OX=9606 GN=FIBP","FIBP",41.878,5.0789,4.4,2,3,2,0.982,0.935,0.92,1.125,0.996,1.048,1.117,0.0531,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0044707 single-multicellular organism process; GO:0065008 regulation of biological quality; GO:0007596 blood coagulation; GO:0007166 cell surface receptor signaling pathway; GO:0071310 cellular response to organic substance; GO:0044699 single-organism process; GO:0071363 cellular response to growth factor stimulus; GO:0050896 response to stimulus; GO:0034109 homotypic cell-cell adhesion; GO:0008543 fibroblast growth factor receptor signaling pathway; GO:0007599 hemostasis; GO:0009611 response to wounding; GO:0022610 biological adhesion; GO:0016337 single organismal cell-cell adhesion; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0071774 response to fibroblast growth factor; GO:0007155 cell adhesion; GO:0009719 response to endogenous stimulus; GO:0070848 response to growth factor; GO:0009987 cellular process; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0070887 cellular response to chemical stimulus; GO:0051716 cellular response to stimulus; GO:0050878 regulation of body fluid levels; GO:0006950 response to stress; GO:0030168 platelet activation; GO:0098609 cell-cell adhesion; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0010033 response to organic substance; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0042060 wound healing; GO:0071495 cellular response to endogenous stimulus; GO:0044344 cellular response to fibroblast growth factor stimulus; GO:0098602 single organism cell adhesion; GO:0001775 cell activation; GO:0050817 coagulation; GO:0070527 platelet aggregation; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0017134 fibroblast growth factor binding; GO:0019838 growth factor binding; GO:0005488 binding; "]
["O43432","Eukaryotic translation initiation factor 4 gamma 3 OS=Homo sapiens OX=9606 GN=EIF4G3","EIF4G3",176.65,7.9232,5.4,8,9,2,0.873,0.893,1.047,1.157,1.022,1.008,1.133,0.155,"nucleus\r","GO:0050794 regulation of cellular process; GO:0006518 peptide metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0010608 posttranscriptional regulation of gene expression; GO:0044267 cellular protein metabolic process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0009889 regulation of biosynthetic process; GO:0016032 viral process; GO:0006413 translational initiation; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006412 translation; GO:0009059 macromolecule biosynthetic process; GO:0044419 interspecies interaction between organisms; GO:0009987 cellular process; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0043043 peptide biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0010556 regulation of macromolecule biosynthetic process; GO:0043603 cellular amide metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0051704 multi-organism process; GO:0034248 regulation of cellular amide metabolic process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006417 regulation of translation; GO:0051246 regulation of protein metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006446 regulation of translational initiation; GO:0019222 regulation of metabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:1901564 organonitrogen compound metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0065007 biological regulation; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0043234 protein complex; GO:0005829 cytosol; GO:0005623 cell; GO:0044444 cytoplasmic part; GO:0016281 eukaryotic translation initiation factor 4F complex; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0008135 translation factor activity, RNA binding; GO:0003723 RNA binding; GO:0000339 RNA cap binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0003743 translation initiation factor activity; GO:0005515 protein binding; ","K03260","EIF4G; translation initiation factor 4G","hsa03013 RNA transport - Homo sapiens (human); hsa05416 Viral myocarditis - Homo sapiens (human); ","IPR003307; IPR003891; IPR016024; IPR003890; IPR016021; ","\"W2 domain; Initiation factor eIF-4 gamma, MA3; Armadillo-type fold; MIF4G-like, type 3; MIF4G-like domain; \"\r"]
["O43447","Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH","PPIH",19.208,6.1773,15.3,3,5,3,0.845,0.899,0.883,1.19,1.088,1.09,1.282,0.00206,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0006725 cellular aromatic compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0006457 protein folding; GO:0000398 mRNA splicing, via spliceosome; GO:0008152 metabolic process; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0022607 cellular component assembly; GO:0006139 nucleobase-containing compound metabolic process; GO:0065003 macromolecular complex assembly; GO:0000375 RNA splicing, via transesterification reactions; GO:0034641 cellular nitrogen compound metabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0045070 positive regulation of viral genome replication; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0006396 RNA processing; GO:1903902 positive regulation of viral life cycle; GO:0043902 positive regulation of multi-organism process; GO:0071822 protein complex subunit organization; GO:0043900 regulation of multi-organism process; GO:0050792 regulation of viral process; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0045069 regulation of viral genome replication; GO:0000413 protein peptidyl-prolyl isomerization; GO:0018208 peptidyl-proline modification; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0043933 macromolecular complex subunit organization; GO:0018193 peptidyl-amino acid modification; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:0050789 regulation of biological process; GO:0048524 positive regulation of viral process; GO:0090304 nucleic acid metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0010467 gene expression; GO:0070271 protein complex biogenesis; GO:1903900 regulation of viral life cycle; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:0016071 mRNA metabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0046540 U4/U6 x U5 tri-snRNP complex; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005681 spliceosomal complex; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0097525 spliceosomal snRNP complex; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0097526 spliceosomal tri-snRNP complex; GO:0043226 organelle; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0005622 intracellular; GO:0044464 cell part; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0030532 small nuclear ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0071001 U4/U6 snRNP; GO:0044428 nuclear part; ","GO:0003755 peptidyl-prolyl cis-trans isomerase activity; GO:0016853 isomerase activity; GO:0042277 peptide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0005515 protein binding; GO:0008144 drug binding; GO:0033218 amide binding; GO:0016018 cyclosporin A binding; GO:0016859 cis-trans isomerase activity; GO:0043021 ribonucleoprotein complex binding; ","K09567","PPIH; peptidyl-prolyl isomerase H (cyclophilin H) [EC:5.2.1.8]","hsa03040 Spliceosome - Homo sapiens (human); ","IPR002130; IPR029000; ","Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain; Cyclophilin-like domain; \r"]
["O43488","Aflatoxin B1 aldehyde reductase member 2 OS=Homo sapiens OX=9606 GN=AKR7A2","AKR7A2",39.589,40.829,21.4,7,13,7,1.179,1.121,1.007,0.917,0.959,0.855,0.826,0.0292,"mitochondria\r","GO:0071466 cellular response to xenobiotic stimulus; GO:0006725 cellular aromatic compound metabolic process; GO:0097164 ammonium ion metabolic process; GO:0044699 single-organism process; GO:0030638 polyketide metabolic process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0006805 xenobiotic metabolic process; GO:0009410 response to xenobiotic stimulus; GO:0042180 cellular ketone metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0016137 glycoside metabolic process; GO:0009987 cellular process; GO:0070887 cellular response to chemical stimulus; GO:0019748 secondary metabolic process; GO:0051716 cellular response to stimulus; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:1901661 quinone metabolic process; GO:0044597 daunorubicin metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0006081 cellular aldehyde metabolic process; GO:0030647 aminoglycoside antibiotic metabolic process; GO:0044238 primary metabolic process; GO:0005975 carbohydrate metabolic process; GO:0051186 cofactor metabolic process; GO:0044598 doxorubicin metabolic process; GO:0042221 response to chemical; GO:0044710 single-organism metabolic process; GO:1901657 glycosyl compound metabolic process; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0005794 Golgi apparatus; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0004032 alditol:NADP+ 1-oxidoreductase activity; GO:0016801 hydrolase activity, acting on ether bonds; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0019119 phenanthrene-9,10-epoxide hydrolase activity; GO:0016491 oxidoreductase activity; GO:0009055 electron carrier activity; GO:0016614 oxidoreductase activity, acting on CH-OH group of donors; GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; GO:0003824 catalytic activity; GO:0004301 epoxide hydrolase activity; GO:0008106 alcohol dehydrogenase (NADP+) activity; GO:0005488 binding; GO:0004033 aldo-keto reductase (NADP) activity; GO:0019118 phenanthrene-epoxide hydrolase activity; GO:0016803 ether hydrolase activity; ","K15303","AKR7; aflatoxin B1 aldehyde reductase","hsa00980 Metabolism of xenobiotics by cytochrome P450 - Homo sapiens (human); ","IPR023210; ","NADP-dependent oxidoreductase domain; \r"]
["O43491","Band 4.1-like protein 2 OS=Homo sapiens OX=9606 GN=EPB41L2","EPB41L2",112.59,135.41,26,24,33,21,1.061,1.05,1.096,0.956,0.904,0.941,0.873,0.003,"nucleus\r","GO:0031032 actomyosin structure organization; GO:0016043 cellular component organization; GO:1902589 single-organism organelle organization; GO:0030036 actin cytoskeleton organization; GO:0030866 cortical actin cytoskeleton organization; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0030865 cortical cytoskeleton organization; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005938 cell cortex; GO:0019898 extrinsic component of membrane; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0099568 cytoplasmic region; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0030863 cortical cytoskeleton; GO:0030864 cortical actin cytoskeleton; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0005925 focal adhesion; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0008091 spectrin; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0015629 actin cytoskeleton; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044448 cell cortex part; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0008092 cytoskeletal protein binding; GO:0005200 structural constituent of cytoskeleton; GO:0042731 PH domain binding; GO:0005488 binding; GO:0003779 actin binding; GO:0005515 protein binding; GO:0019904 protein domain specific binding; GO:0005198 structural molecule activity; GO:0030507 spectrin binding; ","K06107",null,null,"IPR019748; IPR018980; IPR019749; IPR018979; IPR008379; IPR029071; IPR011993; IPR007477; IPR014847; IPR000299; IPR014352; ","\"FERM central domain; FERM, C-terminal PH-like domain; Band 4.1 domain; FERM, N-terminal; Band 4.1, C-terminal; Ubiquitin-related domain; PH domain-like; SAB domain; FERM adjacent (FA); FERM domain; FERM/acyl-CoA-binding protein, 3-helical bundle; \"\r"]
["O43493","Trans-Golgi network integral membrane protein 2 OS=Homo sapiens OX=9606 GN=TGOLN2","TGOLN2",51.018,8.688,5.8,3,5,3,0.987,0.994,1.058,1.094,1.027,0.932,1.005,0.957,"extracellular\r","GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0006895 Golgi to endosome transport; GO:0016192 vesicle-mediated transport; GO:0048193 Golgi vesicle transport; GO:0051234 establishment of localization; GO:0051641 cellular localization; GO:0016197 endosomal transport; GO:0006810 transport; GO:0051649 establishment of localization in cell; GO:0061024 membrane organization; GO:0051179 localization; GO:0016482 cytosolic transport; GO:0006892 post-Golgi vesicle-mediated transport; GO:0009987 cellular process; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0030662 coated vesicle membrane; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0030140 trans-Golgi network transport vesicle; GO:0070013 intracellular organelle lumen; GO:0030136 clathrin-coated vesicle; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0098791 Golgi subcompartment; GO:0044431 Golgi apparatus part; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0016021 integral component of membrane; GO:0030665 clathrin-coated vesicle membrane; GO:0030135 coated vesicle; GO:0005798 Golgi-associated vesicle; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005802 trans-Golgi network; GO:0030133 transport vesicle; GO:0005794 Golgi apparatus; GO:0031984 organelle subcompartment; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0005488 binding; "]
["O43504","Ragulator complex protein LAMTOR5 OS=Homo sapiens OX=9606 GN=LAMTOR5","LAMTOR5",9.6138,31.365,54.9,3,3,3,0.98,1.035,0.943,0.997,1.014,1.04,1.031,0.348,"cytoskeleton\r","GO:0001101 response to acid chemical; GO:0065008 regulation of biological quality; GO:0019079 viral genome replication; GO:0010941 regulation of cell death; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0006914 autophagy; GO:0044237 cellular metabolic process; GO:0009607 response to biotic stimulus; GO:0009605 response to external stimulus; GO:0010466 negative regulation of peptidase activity; GO:0008152 metabolic process; GO:0010646 regulation of cell communication; GO:0032535 regulation of cellular component size; GO:0044093 positive regulation of molecular function; GO:0009719 response to endogenous stimulus; GO:0033365 protein localization to organelle; GO:0044419 interspecies interaction between organisms; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0051726 regulation of cell cycle; GO:0070887 cellular response to chemical stimulus; GO:0016236 macroautophagy; GO:0052548 regulation of endopeptidase activity; GO:0043200 response to amino acid; GO:0051716 cellular response to stimulus; GO:0061462 protein localization to lysosome; GO:2000116 regulation of cysteine-type endopeptidase activity; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051704 multi-organism process; GO:0071417 cellular response to organonitrogen compound; GO:0072665 protein localization to vacuole; GO:0010243 response to organonitrogen compound; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:1901699 cellular response to nitrogen compound; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0071230 cellular response to amino acid stimulus; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0043087 regulation of GTPase activity; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0052547 regulation of peptidase activity; GO:0060548 negative regulation of cell death; GO:0009615 response to virus; GO:0050794 regulation of cellular process; GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0016043 cellular component organization; GO:0045786 negative regulation of cell cycle; GO:0010951 negative regulation of endopeptidase activity; GO:0043069 negative regulation of programmed cell death; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0019058 viral life cycle; GO:1901700 response to oxygen-containing compound; GO:0043067 regulation of programmed cell death; GO:0043207 response to external biotic stimulus; GO:0031324 negative regulation of cellular metabolic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0051346 negative regulation of hydrolase activity; GO:0032006 regulation of TOR signaling; GO:0008361 regulation of cell size; GO:0071229 cellular response to acid chemical; GO:0043066 negative regulation of apoptotic process; GO:0051345 positive regulation of hydrolase activity; GO:0023056 positive regulation of signaling; GO:0016032 viral process; GO:2000117 negative regulation of cysteine-type endopeptidase activity; GO:0044248 cellular catabolic process; GO:0010647 positive regulation of cell communication; GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0034613 cellular protein localization; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:0045861 negative regulation of proteolysis; GO:1902531 regulation of intracellular signal transduction; GO:0043547 positive regulation of GTPase activity; GO:0007050 cell cycle arrest; GO:0032008 positive regulation of TOR signaling; GO:0010033 response to organic substance; GO:0030162 regulation of proteolysis; GO:0048518 positive regulation of biological process; GO:0009892 negative regulation of metabolic process; GO:0051641 cellular localization; GO:0043085 positive regulation of catalytic activity; GO:0070727 cellular macromolecule localization; GO:1901701 cellular response to oxygen-containing compound; GO:0071495 cellular response to endogenous stimulus; GO:0051246 regulation of protein metabolic process; GO:0090066 regulation of anatomical structure size; GO:0051248 negative regulation of protein metabolic process; GO:0022402 cell cycle process; GO:0009967 positive regulation of signal transduction; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0098857 membrane microdomain; GO:0071986 Ragulator complex; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005765 lysosomal membrane; GO:0005622 intracellular; GO:0031902 late endosome membrane; GO:0044425 membrane part; GO:0044464 cell part; GO:0005764 lysosome; GO:0098805 whole membrane; GO:0098589 membrane region; GO:0005768 endosome; GO:0045121 membrane raft; GO:0043227 membrane-bounded organelle; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0010008 endosome membrane; GO:0098588 bounding membrane of organelle; GO:0005770 late endosome; GO:0044446 intracellular organelle part; GO:0044440 endosomal part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0098852 lytic vacuole membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ","K16344","LAMTOR5; ragulator complex protein LAMTOR5","hsa05161 Hepatitis B - Homo sapiens (human); hsa04150 mTOR signaling pathway - Homo sapiens (human); "]
["O43583","Density-regulated protein OS=Homo sapiens OX=9606 GN=DENR","DENR",22.092,1.8868,4,1,2,1,0.898,1.054,0.859,1.015,1.146,1.031,1.136,0.15,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0016043 cellular component organization; GO:0022613 ribonucleoprotein complex biogenesis; GO:0006518 peptide metabolic process; GO:0022618 ribonucleoprotein complex assembly; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:1903008 organelle disassembly; GO:0002188 translation reinitiation; GO:0009058 biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:0032790 ribosome disassembly; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0071826 ribonucleoprotein complex subunit organization; GO:0002181 cytoplasmic translation; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0006413 translational initiation; GO:0002190 cap-independent translational initiation; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006412 translation; GO:0009059 macromolecule biosynthetic process; GO:0002183 cytoplasmic translational initiation; GO:0009987 cellular process; GO:0034622 cellular macromolecular complex assembly; GO:0002192 IRES-dependent translational initiation; GO:0043043 peptide biosynthetic process; GO:0044763 single-organism cellular process; GO:0032984 macromolecular complex disassembly; GO:0006807 nitrogen compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:1902589 single-organism organelle organization; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0006996 organelle organization; GO:0001731 formation of translation preinitiation complex; GO:0044260 cellular macromolecule metabolic process; GO:0022411 cellular component disassembly; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0032988 ribonucleoprotein complex disassembly; GO:0071840 cellular component organization or biogenesis; GO:1901564 organonitrogen compound metabolic process; ","GO:0070992 translation initiation complex; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:1990904 ribonucleoprotein complex; GO:0005623 cell; GO:0030529 intracellular ribonucleoprotein complex; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0043022 ribosome binding; GO:0008135 translation factor activity, RNA binding; GO:0003729 mRNA binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0044877 macromolecular complex binding; GO:0003743 translation initiation factor activity; GO:0005515 protein binding; GO:0043021 ribonucleoprotein complex binding; ",{"$nulls":3},"IPR001950; ","SUI1 domain; \r"]
["O43592","Exportin-T OS=Homo sapiens OX=9606 GN=XPOT","XPOT",109.96,40.449,8.2,7,13,7,0.949,0.997,0.94,1.054,0.989,1.052,1.072,0.0656,"cytoplasm\r","GO:0050658 RNA transport; GO:0046907 intracellular transport; GO:0044699 single-organism process; GO:0051168 nuclear export; GO:0051169 nuclear transport; GO:0071528 tRNA re-export from nucleus; GO:0015031 protein transport; GO:0051236 establishment of RNA localization; GO:0051234 establishment of localization; GO:0071431 tRNA-containing ribonucleoprotein complex export from nucleus; GO:0051649 establishment of localization in cell; GO:1902578 single-organism localization; GO:0050657 nucleic acid transport; GO:0015931 nucleobase-containing compound transport; GO:0006886 intracellular protein transport; GO:1902580 single-organism cellular localization; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0034613 cellular protein localization; GO:0044765 single-organism transport; GO:0051031 tRNA transport; GO:0006403 RNA localization; GO:0006405 RNA export from nucleus; GO:0071702 organic substance transport; GO:0006611 protein export from nucleus; GO:0071166 ribonucleoprotein complex localization; GO:1902582 single-organism intracellular transport; GO:0051641 cellular localization; GO:0006810 transport; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0071426 ribonucleoprotein complex export from nucleus; GO:0006409 tRNA export from nucleus; GO:0006913 nucleocytoplasmic transport; GO:0051179 localization; GO:0071705 nitrogen compound transport; ","GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0016363 nuclear matrix; GO:0034399 nuclear periphery; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0031267 small GTPase binding; GO:0003723 RNA binding; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0015932 nucleobase-containing compound transmembrane transporter activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0000049 tRNA binding; GO:0017016 Ras GTPase binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0008536 Ran GTPase binding; GO:0051020 GTPase binding; GO:0019899 enzyme binding; GO:0022857 transmembrane transporter activity; GO:0005215 transporter activity; ","K14288","XPOT; exportin-T","hsa03013 RNA transport - Homo sapiens (human); ","IPR001494; IPR011989; IPR013598; IPR016024; ","\"Importin-beta, N-terminal domain; Armadillo-like helical; Exportin-1/Importin-beta-like; Armadillo-type fold; \"\r"]
["O43598","2'-deoxynucleoside 5'-phosphate N-hydrolase 1 OS=Homo sapiens OX=9606 GN=DNPH1","DNPH1",19.108,14.383,25.3,3,3,3,0.988,1.045,1.028,0.953,0.965,1.032,0.964,0.279,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0040008 regulation of growth; GO:0006725 cellular aromatic compound metabolic process; GO:0046434 organophosphate catabolic process; GO:0048869 cellular developmental process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0045927 positive regulation of growth; GO:0071704 organic substance metabolic process; GO:0001558 regulation of cell growth; GO:0044270 cellular nitrogen compound catabolic process; GO:0030154 cell differentiation; GO:0009162 deoxyribonucleoside monophosphate metabolic process; GO:0008152 metabolic process; GO:1901292 nucleoside phosphate catabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:1901361 organic cyclic compound catabolic process; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0009159 deoxyribonucleoside monophosphate catabolic process; GO:0009888 tissue development; GO:0030307 positive regulation of cell growth; GO:0044712 single-organism catabolic process; GO:0009125 nucleoside monophosphate catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0008283 cell proliferation; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0050789 regulation of biological process; GO:0006793 phosphorus metabolic process; GO:0044767 single-organism developmental process; GO:0044710 single-organism metabolic process; GO:0019637 organophosphate metabolic process; GO:0051128 regulation of cellular component organization; GO:0048856 anatomical structure development; GO:0009056 catabolic process; GO:0030855 epithelial cell differentiation; GO:0065007 biological regulation; GO:0046700 heterocycle catabolic process; GO:0009123 nucleoside monophosphate metabolic process; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0016763 transferase activity, transferring pentosyl groups; GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0016798 hydrolase activity, acting on glycosyl bonds; GO:0046983 protein dimerization activity; GO:0070694 deoxyribonucleoside 5'-monophosphate N-glycosidase activity; GO:0016757 transferase activity, transferring glycosyl groups; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0050144 nucleoside deoxyribosyltransferase activity; GO:0016740 transferase activity; "]
["O43615","Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44","TIMM44",51.355,60.886,20.8,8,11,8,0.879,0.997,1.051,1.104,0.971,1.026,1.059,0.413,"mitochondria\r","GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0072594 establishment of protein localization to organelle; GO:0017038 protein import; GO:0006839 mitochondrial transport; GO:0044699 single-organism process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0051649 establishment of localization in cell; GO:1902578 single-organism localization; GO:1990542 mitochondrial transmembrane transport; GO:0007005 mitochondrion organization; GO:0065002 intracellular protein transmembrane transport; GO:0006886 intracellular protein transport; GO:0006626 protein targeting to mitochondrion; GO:1902580 single-organism cellular localization; GO:0033365 protein localization to organelle; GO:0044743 protein transmembrane import into intracellular organelle; GO:0034613 cellular protein localization; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0009987 cellular process; GO:0044765 single-organism transport; GO:0030150 protein import into mitochondrial matrix; GO:0071806 protein transmembrane transport; GO:0071702 organic substance transport; GO:0070585 protein localization to mitochondrion; GO:1902582 single-organism intracellular transport; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:0055085 transmembrane transport; GO:0070727 cellular macromolecule localization; GO:0006996 organelle organization; GO:0051179 localization; GO:0072655 establishment of protein localization to mitochondrion; GO:0071840 cellular component organization or biogenesis; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044429 mitochondrial part; GO:0031090 organelle membrane; GO:0031967 organelle envelope; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0031975 envelope; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0051087 chaperone binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K17804",null,null,"IPR007379; IPR032710; ","Tim44-like domain; NTF2-like domain; \r"]
["O43633","Charged multivesicular body protein 2a OS=Homo sapiens OX=9606 GN=CHMP2A","CHMP2A",25.104,17.554,8.6,1,1,1,0.828,1.064,0.891,1.215,1.063,0.947,1.159,0.227,"cytoplasm\r","GO:0060627 regulation of vesicle-mediated transport; GO:0044085 cellular component biogenesis; GO:0010941 regulation of cell death; GO:1902116 negative regulation of organelle assembly; GO:0006914 autophagy; GO:0044237 cellular metabolic process; GO:0010564 regulation of cell cycle process; GO:0015031 protein transport; GO:0008152 metabolic process; GO:0032879 regulation of localization; GO:0010824 regulation of centrosome duplication; GO:0065003 macromolecular complex assembly; GO:0036258 multivesicular body assembly; GO:0044770 cell cycle phase transition; GO:0010458 exit from mitosis; GO:0051493 regulation of cytoskeleton organization; GO:0008104 protein localization; GO:0044419 interspecies interaction between organisms; GO:0031468 nuclear envelope reassembly; GO:1903543 positive regulation of exosomal secretion; GO:0000278 mitotic cell cycle; GO:0007059 chromosome segregation; GO:1901673 regulation of mitotic spindle assembly; GO:0045921 positive regulation of exocytosis; GO:0007088 regulation of mitotic nuclear division; GO:0039702 viral budding via host ESCRT complex; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0051704 multi-organism process; GO:0051291 protein heterooligomerization; GO:0032886 regulation of microtubule-based process; GO:0006810 transport; GO:0010948 negative regulation of cell cycle process; GO:0051301 cell division; GO:0060548 negative regulation of cell death; GO:0051047 positive regulation of secretion; GO:0046605 regulation of centrosome cycle; GO:0051640 organelle localization; GO:0050794 regulation of cellular process; GO:0007346 regulation of mitotic cell cycle; GO:0051260 protein homooligomerization; GO:0017157 regulation of exocytosis; GO:0000920 cell separation after cytokinesis; GO:0007080 mitotic metaphase plate congression; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:1903541 regulation of exosomal secretion; GO:1903047 mitotic cell cycle process; GO:0051259 protein oligomerization; GO:0044248 cellular catabolic process; GO:0006461 protein complex assembly; GO:0044772 mitotic cell cycle phase transition; GO:0010826 negative regulation of centrosome duplication; GO:0043900 regulation of multi-organism process; GO:0016192 vesicle-mediated transport; GO:0032984 macromolecular complex disassembly; GO:1902188 positive regulation of viral release from host cell; GO:0071702 organic substance transport; GO:0051656 establishment of organelle localization; GO:0045184 establishment of protein localization; GO:1902186 regulation of viral release from host cell; GO:0090224 regulation of spindle organization; GO:1903722 regulation of centriole elongation; GO:0051276 chromosome organization; GO:0006996 organelle organization; GO:0098813 nuclear chromosome segregation; GO:0006900 membrane budding; GO:0061024 membrane organization; GO:0000280 nuclear division; GO:0051179 localization; GO:0010256 endomembrane system organization; GO:0040017 positive regulation of locomotion; GO:0007067 mitotic nuclear division; GO:0051129 negative regulation of cellular component organization; GO:0044699 single-organism process; GO:0051046 regulation of secretion; GO:0044764 multi-organism cellular process; GO:0060236 regulation of mitotic spindle organization; GO:1902115 regulation of organelle assembly; GO:0043241 protein complex disassembly; GO:0046599 regulation of centriole replication; GO:0051234 establishment of localization; GO:0000819 sister chromatid segregation; GO:0050000 chromosome localization; GO:0051783 regulation of nuclear division; GO:0051649 establishment of localization in cell; GO:1904896 ESCRT complex disassembly; GO:0022607 cellular component assembly; GO:0033036 macromolecule localization; GO:0051726 regulation of cell cycle; GO:0016236 macroautophagy; GO:1903902 positive regulation of viral life cycle; GO:0043902 positive regulation of multi-organism process; GO:0071822 protein complex subunit organization; GO:0051494 negative regulation of cytoskeleton organization; GO:0048522 positive regulation of cellular process; GO:0036257 multivesicular body organization; GO:1903530 regulation of secretion by cell; GO:0051050 positive regulation of transport; GO:0016197 endosomal transport; GO:0010639 negative regulation of organelle organization; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:1903532 positive regulation of secretion by cell; GO:0051258 protein polymerization; GO:0046606 negative regulation of centrosome cycle; GO:0070271 protein complex biogenesis; GO:0006997 nucleus organization; GO:0016043 cellular component organization; GO:0045786 negative regulation of cell cycle; GO:0019068 virion assembly; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0048285 organelle fission; GO:0019058 viral life cycle; GO:0010324 membrane invagination; GO:0044087 regulation of cellular component biogenesis; GO:1902592 multi-organism membrane budding; GO:0051310 metaphase plate congression; GO:0006998 nuclear envelope organization; GO:0070925 organelle assembly; GO:0016032 viral process; GO:0046600 negative regulation of centriole replication; GO:0009987 cellular process; GO:0043623 cellular protein complex assembly; GO:0034622 cellular macromolecular complex assembly; GO:0070507 regulation of microtubule cytoskeleton organization; GO:0051303 establishment of chromosome localization; GO:0044803 multi-organism membrane organization; GO:0051049 regulation of transport; GO:0050792 regulation of viral process; GO:0033043 regulation of organelle organization; GO:0000070 mitotic sister chromatid segregation; GO:0016050 vesicle organization; GO:0044802 single-organism membrane organization; GO:1903723 negative regulation of centriole elongation; GO:0048518 positive regulation of biological process; GO:1902590 multi-organism organelle organization; GO:0051641 cellular localization; GO:0043933 macromolecular complex subunit organization; GO:0090169 regulation of spindle assembly; GO:0048524 positive regulation of viral process; GO:0046755 viral budding; GO:0007034 vacuolar transport; GO:1904903 ESCRT III complex disassembly; GO:0022411 cellular component disassembly; GO:0051128 regulation of cellular component organization; GO:0022402 cell cycle process; GO:1903900 regulation of viral life cycle; GO:0040012 regulation of locomotion; GO:0007032 endosome organization; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0044089 positive regulation of cellular component biogenesis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0036452 ESCRT complex; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0031902 late endosome membrane; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0000815 ESCRT III complex; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0010008 endosome membrane; GO:0005770 late endosome; GO:0098588 bounding membrane of organelle; GO:0005635 nuclear envelope; GO:0048475 coated membrane; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0031975 envelope; GO:0030117 membrane coat; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0031210 phosphatidylcholine binding; GO:0050997 quaternary ammonium group binding; GO:0070405 ammonium ion binding; GO:0005488 binding; GO:0005543 phospholipid binding; GO:0043167 ion binding; GO:0008289 lipid binding; GO:0043169 cation binding; GO:0019904 protein domain specific binding; GO:0043168 anion binding; GO:0005515 protein binding; ","K12191","CHMP2A; charged multivesicular body protein 2A","hsa04144 Endocytosis - Homo sapiens (human); hsa04217 Necroptosis - Homo sapiens (human); "]
["O43660","Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1","PLRG1",57.193,4.8798,4.7,3,3,3,0.842,0.811,0.919,1.07,1.155,1.186,1.326,0.00422,"nucleus\r","GO:0050794 regulation of cellular process; GO:2000045 regulation of G1/S transition of mitotic cell cycle; GO:0007346 regulation of mitotic cell cycle; GO:0006725 cellular aromatic compound metabolic process; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:1901989 positive regulation of cell cycle phase transition; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0008152 metabolic process; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901987 regulation of cell cycle phase transition; GO:0000375 RNA splicing, via transesterification reactions; GO:1902806 regulation of cell cycle G1/S phase transition; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0034641 cellular nitrogen compound metabolic process; GO:0033365 protein localization to organelle; GO:0043170 macromolecule metabolic process; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0034613 cellular protein localization; GO:0090068 positive regulation of cell cycle process; GO:0008380 RNA splicing; GO:0051726 regulation of cell cycle; GO:0009987 cellular process; GO:0045787 positive regulation of cell cycle; GO:0006396 RNA processing; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:1900087 positive regulation of G1/S transition of mitotic cell cycle; GO:0070727 cellular macromolecule localization; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0045931 positive regulation of mitotic cell cycle; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0051179 localization; GO:1902808 positive regulation of cell cycle G1/S phase transition; GO:0034504 protein localization to nucleus; GO:1901992 positive regulation of mitotic cell cycle phase transition; GO:0016071 mRNA metabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0080008 Cul4-RING E3 ubiquitin ligase complex; GO:0031090 organelle membrane; GO:0000974 Prp19 complex; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0071011 precatalytic spliceosome; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0031965 nuclear membrane; GO:0005654 nucleoplasm; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0000151 ubiquitin ligase complex; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005635 nuclear envelope; GO:0043232 intracellular non-membrane-bounded organelle; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0031461 cullin-RING ubiquitin ligase complex; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0044452 nucleolar part; GO:1990234 transferase complex; GO:0005681 spliceosomal complex; GO:0005730 nucleolus; GO:0001650 fibrillar center; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0031975 envelope; GO:0071013 catalytic step 2 spliceosome; GO:1990904 ribonucleoprotein complex; GO:0043234 protein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0005488 binding; ","K12862","PLRG1; pleiotropic regulator 1","hsa03040 Spliceosome - Homo sapiens (human); ","IPR017986; IPR015943; ","WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain; \r"]
["O43670","BUB3-interacting and GLEBS motif-containing protein ZNF207 OS=Homo sapiens OX=9606 GN=ZNF207","ZNF207",50.75,13.621,6.9,3,4,3,0.968,0.873,0.963,1.004,1.098,1.089,1.138,0.0424,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0031109 microtubule polymerization or depolymerization; GO:0007067 mitotic nuclear division; GO:0051129 negative regulation of cellular component organization; GO:0044699 single-organism process; GO:0030071 regulation of mitotic metaphase/anaphase transition; GO:0010564 regulation of cell cycle process; GO:1902100 negative regulation of metaphase/anaphase transition of cell cycle; GO:0033048 negative regulation of mitotic sister chromatid segregation; GO:2001141 regulation of RNA biosynthetic process; GO:0000819 sister chromatid segregation; GO:0045930 negative regulation of mitotic cell cycle; GO:0051783 regulation of nuclear division; GO:0051225 spindle assembly; GO:0031577 spindle checkpoint; GO:0022607 cellular component assembly; GO:1901991 negative regulation of mitotic cell cycle phase transition; GO:0065003 macromolecular complex assembly; GO:0008608 attachment of spindle microtubules to kinetochore; GO:0051784 negative regulation of nuclear division; GO:0000075 cell cycle checkpoint; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0051726 regulation of cell cycle; GO:0000278 mitotic cell cycle; GO:0010468 regulation of gene expression; GO:0033045 regulation of sister chromatid segregation; GO:0007059 chromosome segregation; GO:0071822 protein complex subunit organization; GO:0031326 regulation of cellular biosynthetic process; GO:0007094 mitotic spindle assembly checkpoint; GO:1905818 regulation of chromosome separation; GO:0080090 regulation of primary metabolic process; GO:0033047 regulation of mitotic sister chromatid segregation; GO:0007088 regulation of mitotic nuclear division; GO:0044763 single-organism cellular process; GO:0045841 negative regulation of mitotic metaphase/anaphase transition; GO:0051985 negative regulation of chromosome segregation; GO:0031323 regulation of cellular metabolic process; GO:0000226 microtubule cytoskeleton organization; GO:1902589 single-organism organelle organization; GO:0010639 negative regulation of organelle organization; GO:1903506 regulation of nucleic acid-templated transcription; GO:0010948 negative regulation of cell cycle process; GO:1905819 negative regulation of chromosome separation; GO:0050789 regulation of biological process; GO:0051258 protein polymerization; GO:0019222 regulation of metabolic process; GO:1902850 microtubule cytoskeleton organization involved in mitosis; GO:0090307 mitotic spindle assembly; GO:0051301 cell division; GO:0046785 microtubule polymerization; GO:0070271 protein complex biogenesis; GO:0045839 negative regulation of mitotic nuclear division; GO:0097435 supramolecular fiber organization; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0007346 regulation of mitotic cell cycle; GO:0045786 negative regulation of cell cycle; GO:1901988 negative regulation of cell cycle phase transition; GO:0060255 regulation of macromolecule metabolic process; GO:0048285 organelle fission; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0007051 spindle organization; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:2000816 negative regulation of mitotic sister chromatid separation; GO:1903047 mitotic cell cycle process; GO:0071174 mitotic spindle checkpoint; GO:0070925 organelle assembly; GO:0009889 regulation of biosynthetic process; GO:1901987 regulation of cell cycle phase transition; GO:0007093 mitotic cell cycle checkpoint; GO:0051171 regulation of nitrogen compound metabolic process; GO:0007052 mitotic spindle organization; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0043623 cellular protein complex assembly; GO:0034622 cellular macromolecular complex assembly; GO:0051983 regulation of chromosome segregation; GO:0006355 regulation of transcription, DNA-templated; GO:0071173 spindle assembly checkpoint; GO:0000070 mitotic sister chromatid segregation; GO:1902099 regulation of metaphase/anaphase transition of cell cycle; GO:0033043 regulation of organelle organization; GO:0010556 regulation of macromolecule biosynthetic process; GO:0007017 microtubule-based process; GO:0051252 regulation of RNA metabolic process; GO:0033044 regulation of chromosome organization; GO:0043933 macromolecular complex subunit organization; GO:0033046 negative regulation of sister chromatid segregation; GO:2001251 negative regulation of chromosome organization; GO:0051276 chromosome organization; GO:0010965 regulation of mitotic sister chromatid separation; GO:0098813 nuclear chromosome segregation; GO:0006996 organelle organization; GO:0000280 nuclear division; GO:0031647 regulation of protein stability; GO:0051128 regulation of cellular component organization; GO:0022402 cell cycle process; GO:0001578 microtubule bundle formation; GO:0050821 protein stabilization; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0005874 microtubule; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0005623 cell; GO:0099080 supramolecular complex; GO:0000777 condensed chromosome kinetochore; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0000793 condensed chromosome; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:1990047 spindle matrix; GO:0043227 membrane-bounded organelle; GO:0000776 kinetochore; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0000779 condensed chromosome, centromeric region; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005819 spindle; GO:0099081 supramolecular polymer; GO:0098687 chromosomal region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0000775 chromosome, centromeric region; GO:0043234 protein complex; GO:0044428 nuclear part; ","GO:0003677 DNA binding; GO:0003723 RNA binding; GO:0043167 ion binding; GO:0015631 tubulin binding; GO:0005515 protein binding; GO:0008201 heparin binding; GO:0008270 zinc ion binding; GO:1901681 sulfur compound binding; GO:0003700 transcription factor activity, sequence-specific DNA binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0097367 carbohydrate derivative binding; GO:0008092 cytoskeletal protein binding; GO:0046914 transition metal ion binding; GO:0008017 microtubule binding; GO:0005488 binding; GO:0001071 nucleic acid binding transcription factor activity; GO:0003676 nucleic acid binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0005539 glycosaminoglycan binding; ",{"$nulls":3},"IPR015880; IPR007087; ","\"Zinc finger, C2H2-like; Zinc finger, C2H2; \"\r"]
["O43676","NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 OS=Homo sapiens OX=9606 GN=NDUFB3","NDUFB3",11.402,8.7279,21.4,2,4,2,0.925,1.096,0.963,1.086,1.01,0.966,1.026,0.68,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0022607 cellular component assembly; GO:0006753 nucleoside phosphate metabolic process; GO:0065003 macromolecular complex assembly; GO:0007005 mitochondrion organization; GO:0019693 ribose phosphate metabolic process; GO:0071822 protein complex subunit organization; GO:0010257 NADH dehydrogenase complex assembly; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0006119 oxidative phosphorylation; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0006120 mitochondrial electron transport, NADH to ubiquinone; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0097031 mitochondrial respiratory chain complex I biogenesis; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0022900 electron transport chain; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0070271 protein complex biogenesis; GO:0033108 mitochondrial respiratory chain complex assembly; GO:0016043 cellular component organization; GO:0016310 phosphorylation; GO:0006725 cellular aromatic compound metabolic process; GO:0042773 ATP synthesis coupled electron transport; GO:0009259 ribonucleotide metabolic process; GO:0022904 respiratory electron transport chain; GO:0071704 organic substance metabolic process; GO:0032981 mitochondrial respiratory chain complex I assembly; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0009119 ribonucleoside metabolic process; GO:0006461 protein complex assembly; GO:0043623 cellular protein complex assembly; GO:0046034 ATP metabolic process; GO:0034622 cellular macromolecular complex assembly; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0045333 cellular respiration; GO:0006163 purine nucleotide metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0046128 purine ribonucleoside metabolic process; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:1901564 organonitrogen compound metabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0045271 respiratory chain complex I; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0098798 mitochondrial protein complex; GO:0005747 mitochondrial respiratory chain complex I; GO:0005623 cell; GO:0044455 mitochondrial membrane part; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0070062 extracellular exosome; GO:1902494 catalytic complex; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0019866 organelle inner membrane; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0098803 respiratory chain complex; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005746 mitochondrial respiratory chain; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0030964 NADH dehydrogenase complex; GO:0031975 envelope; GO:1990204 oxidoreductase complex; GO:0043234 protein complex; GO:0031966 mitochondrial membrane; GO:0070469 respiratory chain; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0050136 NADH dehydrogenase (quinone) activity; GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:0003954 NADH dehydrogenase activity; GO:0003824 catalytic activity; GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; GO:0008137 NADH dehydrogenase (ubiquinone) activity; GO:0016491 oxidoreductase activity; ","K03959","NDUFB3; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3","hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); "]
["O43678","NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 OS=Homo sapiens OX=9606 GN=NDUFA2","NDUFA2",10.921,16.75,47.5,4,6,4,1.011,0.986,0.996,1.013,1.032,0.973,1.008,0.69,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0022607 cellular component assembly; GO:0006753 nucleoside phosphate metabolic process; GO:0065003 macromolecular complex assembly; GO:0007005 mitochondrion organization; GO:0019693 ribose phosphate metabolic process; GO:0071822 protein complex subunit organization; GO:0010257 NADH dehydrogenase complex assembly; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0006119 oxidative phosphorylation; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0006120 mitochondrial electron transport, NADH to ubiquinone; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0097031 mitochondrial respiratory chain complex I biogenesis; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0022900 electron transport chain; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0070271 protein complex biogenesis; GO:0033108 mitochondrial respiratory chain complex assembly; GO:0016043 cellular component organization; GO:0016310 phosphorylation; GO:0006725 cellular aromatic compound metabolic process; GO:0042773 ATP synthesis coupled electron transport; GO:0009259 ribonucleotide metabolic process; GO:0022904 respiratory electron transport chain; GO:0071704 organic substance metabolic process; GO:0032981 mitochondrial respiratory chain complex I assembly; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0009119 ribonucleoside metabolic process; GO:0006461 protein complex assembly; GO:0043623 cellular protein complex assembly; GO:0046034 ATP metabolic process; GO:0034622 cellular macromolecular complex assembly; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0045333 cellular respiration; GO:0006163 purine nucleotide metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0046128 purine ribonucleoside metabolic process; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:1901564 organonitrogen compound metabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0045271 respiratory chain complex I; GO:0044424 intracellular part; GO:0098798 mitochondrial protein complex; GO:0005747 mitochondrial respiratory chain complex I; GO:0005623 cell; GO:0044455 mitochondrial membrane part; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:1902494 catalytic complex; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0098803 respiratory chain complex; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005739 mitochondrion; GO:0005746 mitochondrial respiratory chain; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0030964 NADH dehydrogenase complex; GO:1990204 oxidoreductase complex; GO:0031975 envelope; GO:0043234 protein complex; GO:0031966 mitochondrial membrane; GO:0070469 respiratory chain; GO:0044444 cytoplasmic part; ","GO:0050136 NADH dehydrogenase (quinone) activity; GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:0003954 NADH dehydrogenase activity; GO:0003824 catalytic activity; GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; GO:0008137 NADH dehydrogenase (ubiquinone) activity; GO:0016491 oxidoreductase activity; ","K03946","NDUFA2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2","hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); ","IPR007741; IPR012336; ","Ribosomal protein/NADH dehydrogenase domain; Thioredoxin-like fold; \r"]
["O43679","LIM domain-binding protein 2 OS=Homo sapiens OX=9606 GN=LDB2","LDB2",42.793,7.0305,3.8,1,2,1,1.02,0.977,0.881,1.019,1.146,0.963,1.087,0.287,"nucleus\r","GO:0065008 regulation of biological quality; GO:0009891 positive regulation of biosynthetic process; GO:0044699 single-organism process; GO:0048871 multicellular organismal homeostasis; GO:2001141 regulation of RNA biosynthetic process; GO:0022404 molting cycle process; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0032879 regulation of localization; GO:0008544 epidermis development; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0032502 developmental process; GO:0042325 regulation of phosphorylation; GO:0060429 epithelium development; GO:0010468 regulation of gene expression; GO:0051174 regulation of phosphorus metabolic process; GO:0043588 skin development; GO:0009888 tissue development; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0048522 positive regulation of cellular process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0098773 skin epidermis development; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0050790 regulation of catalytic activity; GO:0001894 tissue homeostasis; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0098727 maintenance of cell number; GO:0065009 regulation of molecular function; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0048856 anatomical structure development; GO:0043549 regulation of kinase activity; GO:0001942 hair follicle development; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0035019 somatic stem cell population maintenance; GO:0060255 regulation of macromolecule metabolic process; GO:0042303 molting cycle; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044087 regulation of cellular component biogenesis; GO:0060249 anatomical structure homeostasis; GO:0042592 homeostatic process; GO:0009889 regulation of biosynthetic process; GO:2000145 regulation of cell motility; GO:0010628 positive regulation of gene expression; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0019827 stem cell population maintenance; GO:1902680 positive regulation of RNA biosynthetic process; GO:0007275 multicellular organism development; GO:0010669 epithelial structure maintenance; GO:0051254 positive regulation of RNA metabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0030334 regulation of cell migration; GO:0010556 regulation of macromolecule biosynthetic process; GO:0022405 hair cycle process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0042633 hair cycle; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0044767 single-organism developmental process; GO:0031325 positive regulation of cellular metabolic process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0040012 regulation of locomotion; GO:0031328 positive regulation of cellular biosynthetic process; GO:0044089 positive regulation of cellular component biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0043229 intracellular organelle; GO:0031252 cell leading edge; GO:0043232 intracellular non-membrane-bounded organelle; GO:0071944 cell periphery; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005730 nucleolus; GO:0005667 transcription factor complex; GO:0005623 cell; GO:0044422 organelle part; GO:0005886 plasma membrane; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0005488 binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0030274 LIM domain binding; GO:0019904 protein domain specific binding; GO:0005515 protein binding; GO:0003712 transcription cofactor activity; GO:0000988 transcription factor activity, protein binding; GO:0019899 enzyme binding; "]
["O43681","ATPase ASNA1 OS=Homo sapiens OX=9606 GN=ASNA1","ASNA1",38.792,18.857,19,6,9,6,0.987,0.995,0.996,0.956,1.017,1.009,1.001,0.965,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0051716 cellular response to stimulus; GO:0033554 cellular response to stress; GO:0006986 response to unfolded protein; GO:0006950 response to stress; GO:0034976 response to endoplasmic reticulum stress; GO:0034620 cellular response to unfolded protein; GO:0035967 cellular response to topologically incorrect protein; GO:0071310 cellular response to organic substance; GO:0044699 single-organism process; GO:0036498 IRE1-mediated unfolded protein response; GO:0010033 response to organic substance; GO:0023052 signaling; GO:0050896 response to stimulus; GO:0030968 endoplasmic reticulum unfolded protein response; GO:0051234 establishment of localization; GO:0006820 anion transport; GO:0006810 transport; GO:0007165 signal transduction; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0035966 response to topologically incorrect protein; GO:0007154 cell communication; GO:0006811 ion transport; GO:0051179 localization; GO:0009987 cellular process; GO:0015698 inorganic anion transport; GO:0070887 cellular response to chemical stimulus; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044432 endoplasmic reticulum part; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0022892 substrate-specific transporter activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0015103 inorganic anion transmembrane transporter activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0016887 ATPase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0043492 ATPase activity, coupled to movement of substances; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005215 transporter activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0015075 ion transmembrane transporter activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0015105 arsenite transmembrane transporter activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0042623 ATPase activity, coupled; GO:0046872 metal ion binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0022857 transmembrane transporter activity; GO:0036094 small molecule binding; GO:0008509 anion transmembrane transporter activity; ","K01551",null,null,"IPR027417; IPR025723; ","P-loop containing nucleoside triphosphate hydrolase; Anion-transporting ATPase-like domain; \r"]
["O43684","Mitotic checkpoint protein BUB3 OS=Homo sapiens OX=9606 GN=BUB3","BUB3",37.154,16.344,20.4,6,8,6,0.865,1.017,0.84,1.124,1.072,1.069,1.199,0.0398,"nucleus\r","GO:0032270 positive regulation of cellular protein metabolic process; GO:0022414 reproductive process; GO:0051443 positive regulation of ubiquitin-protein transferase activity; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:1903364 positive regulation of cellular protein catabolic process; GO:0008152 metabolic process; GO:0031577 spindle checkpoint; GO:0008608 attachment of spindle microtubules to kinetochore; GO:0044702 single organism reproductive process; GO:0044093 positive regulation of molecular function; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0051347 positive regulation of transferase activity; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:1903362 regulation of cellular protein catabolic process; GO:0000278 mitotic cell cycle; GO:0007059 chromosome segregation; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:2000058 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:1901575 organic substance catabolic process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0030163 protein catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:0006464 cellular protein modification process; GO:0031145 anaphase-promoting complex-dependent catabolic process; GO:0051301 cell division; GO:0000003 reproduction; GO:0050794 regulation of cellular process; GO:0007346 regulation of mitotic cell cycle; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:1901987 regulation of cell cycle phase transition; GO:0009896 positive regulation of catabolic process; GO:0051338 regulation of transferase activity; GO:0044248 cellular catabolic process; GO:0042176 regulation of protein catabolic process; GO:0071173 spindle assembly checkpoint; GO:0016567 protein ubiquitination; GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1904666 regulation of ubiquitin protein ligase activity; GO:1903321 negative regulation of protein modification by small protein conjugation or removal; GO:0051247 positive regulation of protein metabolic process; GO:0051276 chromosome organization; GO:0051438 regulation of ubiquitin-protein transferase activity; GO:0031398 positive regulation of protein ubiquitination; GO:0032446 protein modification by small protein conjugation; GO:0098813 nuclear chromosome segregation; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:1904668 positive regulation of ubiquitin protein ligase activity; GO:0000280 nuclear division; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0007062 sister chromatid cohesion; GO:0043412 macromolecule modification; GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process; GO:0051444 negative regulation of ubiquitin-protein transferase activity; GO:0007067 mitotic nuclear division; GO:0031331 positive regulation of cellular catabolic process; GO:0044699 single-organism process; GO:0031400 negative regulation of protein modification process; GO:0031396 regulation of protein ubiquitination; GO:0000819 sister chromatid segregation; GO:0009893 positive regulation of metabolic process; GO:0000075 cell cycle checkpoint; GO:0051726 regulation of cell cycle; GO:0048522 positive regulation of cellular process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0051321 meiotic cell cycle; GO:0051348 negative regulation of transferase activity; GO:0010605 negative regulation of macromolecule metabolic process; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0036211 protein modification process; GO:0016043 cellular component organization; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0045786 negative regulation of cell cycle; GO:0044257 cellular protein catabolic process; GO:1904667 negative regulation of ubiquitin protein ligase activity; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:0060255 regulation of macromolecule metabolic process; GO:0048285 organelle fission; GO:0031324 negative regulation of cellular metabolic process; GO:0010498 proteasomal protein catabolic process; GO:0071704 organic substance metabolic process; GO:1903322 positive regulation of protein modification by small protein conjugation or removal; GO:0045862 positive regulation of proteolysis; GO:0006508 proteolysis; GO:0009987 cellular process; GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:0043632 modification-dependent macromolecule catabolic process; GO:0031397 negative regulation of protein ubiquitination; GO:0051983 regulation of chromosome segregation; GO:0044265 cellular macromolecule catabolic process; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0019941 modification-dependent protein catabolic process; GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition; GO:0031401 positive regulation of protein modification process; GO:0000070 mitotic sister chromatid segregation; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0051246 regulation of protein metabolic process; GO:0009057 macromolecule catabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0022402 cell cycle process; GO:0045732 positive regulation of protein catabolic process; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0000777 condensed chromosome kinetochore; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0044427 chromosomal part; GO:0031974 membrane-enclosed lumen; GO:0000793 condensed chromosome; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0043227 membrane-bounded organelle; GO:0000776 kinetochore; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0000779 condensed chromosome, centromeric region; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0098687 chromosomal region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0000775 chromosome, centromeric region; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0005488 binding; ","K02180","BUB3; cell cycle arrest protein BUB3","hsa04110 Cell cycle - Homo sapiens (human); hsa05166 HTLV-I infection - Homo sapiens (human); ","IPR017986; IPR015943; ","WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain; \r"]
["O43707","Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4","ACTN4",104.85,323.31,66.2,56,148,37,1.029,1.005,1.012,0.982,0.989,0.993,0.973,0.0243,"cytoplasm\r","GO:0060627 regulation of vesicle-mediated transport; GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0030335 positive regulation of cell migration; GO:1901224 positive regulation of NIK/NF-kappaB signaling; GO:0015031 protein transport; GO:0048549 positive regulation of pinocytosis; GO:0030036 actin cytoskeleton organization; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0030522 intracellular receptor signaling pathway; GO:0032414 positive regulation of ion transmembrane transporter activity; GO:0008104 protein localization; GO:0030050 vesicle transport along actin filament; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0043269 regulation of ion transport; GO:0044763 single-organism cellular process; GO:2000649 regulation of sodium ion transmembrane transporter activity; GO:0051272 positive regulation of cellular component movement; GO:0031323 regulation of cellular metabolic process; GO:0034762 regulation of transmembrane transport; GO:0006810 transport; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048384 retinoic acid receptor signaling pathway; GO:0048583 regulation of response to stimulus; GO:0032412 regulation of ion transmembrane transporter activity; GO:0010721 negative regulation of cell development; GO:0097435 supramolecular fiber organization; GO:0051640 organelle localization; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0002028 regulation of sodium ion transport; GO:0034764 positive regulation of transmembrane transport; GO:0007162 negative regulation of cell adhesion; GO:0009628 response to abiotic stimulus; GO:0043067 regulation of programmed cell death; GO:0002576 platelet degranulation; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:2000147 positive regulation of cell motility; GO:0030705 cytoskeleton-dependent intracellular transport; GO:1902578 single-organism localization; GO:0009889 regulation of biosynthetic process; GO:2000145 regulation of cell motility; GO:0070482 response to oxygen levels; GO:1900024 regulation of substrate adhesion-dependent cell spreading; GO:0051171 regulation of nitrogen compound metabolic process; GO:0010959 regulation of metal ion transport; GO:1902580 single-organism cellular localization; GO:0007010 cytoskeleton organization; GO:0009966 regulation of signal transduction; GO:0032409 regulation of transporter activity; GO:1904062 regulation of cation transmembrane transport; GO:0043297 apical junction assembly; GO:0010771 negative regulation of cell morphogenesis involved in differentiation; GO:0030100 regulation of endocytosis; GO:1902531 regulation of intracellular signal transduction; GO:0006950 response to stress; GO:1901222 regulation of NIK/NF-kappaB signaling; GO:0051270 regulation of cellular component movement; GO:0060284 regulation of cell development; GO:0016192 vesicle-mediated transport; GO:0030334 regulation of cell migration; GO:0071702 organic substance transport; GO:0051656 establishment of organelle localization; GO:0030155 regulation of cell adhesion; GO:0061572 actin filament bundle organization; GO:0045184 establishment of protein localization; GO:0043270 positive regulation of ion transport; GO:0045055 regulated exocytosis; GO:0032415 regulation of sodium:proton antiporter activity; GO:1904064 positive regulation of cation transmembrane transport; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0006928 movement of cell or subcellular component; GO:1902305 regulation of sodium ion transmembrane transport; GO:0036293 response to decreased oxygen levels; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:0010810 regulation of cell-substrate adhesion; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:0050793 regulation of developmental process; GO:0006887 exocytosis; GO:0030048 actin filament-based movement; GO:0051093 negative regulation of developmental process; GO:0040017 positive regulation of locomotion; GO:0023051 regulation of signaling; GO:0051129 negative regulation of cellular component organization; GO:1902533 positive regulation of intracellular signal transduction; GO:0045216 cell-cell junction organization; GO:0044699 single-organism process; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:1900025 negative regulation of substrate adhesion-dependent cell spreading; GO:0051649 establishment of localization in cell; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0010765 positive regulation of sodium ion transport; GO:0099515 actin filament-based transport; GO:0033036 macromolecule localization; GO:0045596 negative regulation of cell differentiation; GO:0051650 establishment of vesicle localization; GO:0031326 regulation of cellular biosynthetic process; GO:0048522 positive regulation of cellular process; GO:0022898 regulation of transmembrane transporter activity; GO:0023052 signaling; GO:1902582 single-organism intracellular transport; GO:0051050 positive regulation of transport; GO:0010155 regulation of proton transport; GO:1902589 single-organism organelle organization; GO:0099518 vesicle cytoskeletal trafficking; GO:0050789 regulation of biological process; GO:0034767 positive regulation of ion transmembrane transport; GO:0032940 secretion by cell; GO:2000651 positive regulation of sodium ion transmembrane transporter activity; GO:1902396 protein localization to bicellular tight junction; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0048548 regulation of pinocytosis; GO:0010812 negative regulation of cell-substrate adhesion; GO:0051271 negative regulation of cellular component movement; GO:0016043 cellular component organization; GO:0034329 cell junction assembly; GO:0032411 positive regulation of transporter activity; GO:0060255 regulation of macromolecule metabolic process; GO:0045807 positive regulation of endocytosis; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0007015 actin filament organization; GO:0035357 peroxisome proliferator activated receptor signaling pathway; GO:0051017 actin filament bundle assembly; GO:0050896 response to stimulus; GO:0023056 positive regulation of signaling; GO:0051648 vesicle localization; GO:0001666 response to hypoxia; GO:0070830 bicellular tight junction assembly; GO:0010647 positive regulation of cell communication; GO:0032417 positive regulation of sodium:proton antiporter activity; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0007043 cell-cell junction assembly; GO:0051049 regulation of transport; GO:0010556 regulation of macromolecule biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0034330 cell junction organization; GO:0034765 regulation of ion transmembrane transport; GO:0022603 regulation of anatomical structure morphogenesis; GO:1902414 protein localization to cell junction; GO:0009967 positive regulation of signal transduction; GO:0051128 regulation of cellular component organization; GO:1902307 positive regulation of sodium ion transmembrane transport; GO:0040012 regulation of locomotion; GO:0022604 regulation of cell morphogenesis; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0098862 cluster of actin-based cell projections; GO:0044421 extracellular region part; GO:0099568 cytoplasmic region; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0031674 I band; GO:0031143 pseudopodium; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0043005 neuron projection; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0042641 actomyosin; GO:0097458 neuron part; GO:0044451 nucleoplasm part; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0042995 cell projection; GO:0044430 cytoskeletal part; GO:0070161 anchoring junction; GO:0031981 nuclear lumen; GO:0005576 extracellular region; GO:0099081 supramolecular polymer; GO:0043231 intracellular membrane-bounded organelle; GO:0044449 contractile fiber part; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0034774 secretory granule lumen; GO:0005615 extracellular space; GO:0005903 brush border; GO:0005938 cell cortex; GO:0031410 cytoplasmic vesicle; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0030016 myofibril; GO:0031982 vesicle; GO:0030863 cortical cytoskeleton; GO:0044424 intracellular part; GO:0099512 supramolecular fiber; GO:0030018 Z disc; GO:0016604 nuclear body; GO:0005911 cell-cell junction; GO:0032432 actin filament bundle; GO:0005856 cytoskeleton; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0043292 contractile fiber; GO:1903561 extracellular vesicle; GO:0005912 adherens junction; GO:0048471 perinuclear region of cytoplasm; GO:0030141 secretory granule; GO:0001725 stress fiber; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0097517 contractile actin filament bundle; GO:0005829 cytosol; GO:0015629 actin cytoskeleton; GO:0043226 organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0044448 cell cortex part; GO:0030017 sarcomere; GO:0031093 platelet alpha granule lumen; GO:0031091 platelet alpha granule; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0051015 actin filament binding; GO:0047485 protein N-terminus binding; GO:0031490 chromatin DNA binding; GO:0005102 receptor binding; GO:0003690 double-stranded DNA binding; GO:0046983 protein dimerization activity; GO:0005178 integrin binding; GO:0005515 protein binding; GO:0051427 hormone receptor binding; GO:0003682 chromatin binding; GO:0000975 regulatory region DNA binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0042974 retinoic acid receptor binding; GO:0042802 identical protein binding; GO:0008092 cytoskeletal protein binding; GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity; GO:0005488 binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0043169 cation binding; GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding; GO:0003723 RNA binding; GO:0003677 DNA binding; GO:0000976 transcription regulatory region sequence-specific DNA binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:1990837 sequence-specific double-stranded DNA binding; GO:0001012 RNA polymerase II regulatory region DNA binding; GO:0044877 macromolecular complex binding; GO:0043565 sequence-specific DNA binding; GO:0003712 transcription cofactor activity; GO:0050839 cell adhesion molecule binding; GO:0097367 carbohydrate derivative binding; GO:0001067 regulatory region nucleic acid binding; GO:0042803 protein homodimerization activity; GO:0044212 transcription regulatory region DNA binding; GO:0003676 nucleic acid binding; GO:0003779 actin binding; GO:0035257 nuclear hormone receptor binding; GO:0044325 ion channel binding; GO:0046872 metal ion binding; GO:0003713 transcription coactivator activity; GO:0005509 calcium ion binding; GO:0000988 transcription factor activity, protein binding; GO:0008134 transcription factor binding; GO:0036094 small molecule binding; GO:0032403 protein complex binding; ","K05699","ACTN1_4; actinin alpha 1/4","hsa05322 Systemic lupus erythematosus - Homo sapiens (human); hsa04530 Tight junction - Homo sapiens (human); hsa05146 Amoebiasis - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa05203 Viral carcinogenesis - Homo sapiens (human); hsa04670 Leukocyte transendothelial migration - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa04520 Adherens junction - Homo sapiens (human); ","IPR014837; IPR002048; IPR001715; IPR011992; ","\"EF-hand, Ca insensitive; EF-hand domain; Calponin homology domain; EF-hand domain pair; \"\r"]
["O43716","Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial OS=Homo sapiens OX=9606 GN=GATC","GATC",15.086,6.8149,14.7,2,3,2,0.808,0.994,1.045,1.022,1.049,1.094,1.112,0.241,"mitochondria\r","GO:0065008 regulation of biological quality; GO:0006518 peptide metabolic process; GO:0010608 posttranscriptional regulation of gene expression; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006412 translation; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0043043 peptide biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0016070 RNA metabolic process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006082 organic acid metabolic process; GO:0043436 oxoacid metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0044267 cellular protein metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0043039 tRNA aminoacylation; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006448 regulation of translational elongation; GO:0006450 regulation of translational fidelity; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0032543 mitochondrial translation; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation; GO:0044249 cellular biosynthetic process; GO:0034248 regulation of cellular amide metabolic process; GO:0006399 tRNA metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0051246 regulation of protein metabolic process; GO:0006417 regulation of translation; GO:0043038 amino acid activation; GO:0019752 carboxylic acid metabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0034660 ncRNA metabolic process; GO:0065007 biological regulation; GO:1901564 organonitrogen compound metabolic process; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0043234 protein complex; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044444 cytoplasmic part; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0016874 ligase activity; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor; GO:0016879 ligase activity, forming carbon-nitrogen bonds; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K02435","gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00970 Aminoacyl-tRNA biosynthesis - Homo sapiens (human); "]
["O43747","AP-1 complex subunit gamma-1 OS=Homo sapiens OX=9606 GN=AP1G1","AP1G1",91.35,100.65,12.3,11,15,11,1.006,0.918,0.948,1.051,1.013,1.011,1.071,0.0808,"mitochondria\r","GO:0060627 regulation of vesicle-mediated transport; GO:0002694 regulation of leukocyte activation; GO:0021700 developmental maturation; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0051046 regulation of secretion; GO:0051249 regulation of lymphocyte activation; GO:0031347 regulation of defense response; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0009605 response to external stimulus; GO:0031343 positive regulation of cell killing; GO:0051649 establishment of localization in cell; GO:0050690 regulation of defense response to virus by virus; GO:1903307 positive regulation of regulated secretory pathway; GO:0045088 regulation of innate immune response; GO:0032879 regulation of localization; GO:0043321 regulation of natural killer cell degranulation; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0002697 regulation of immune effector process; GO:0002708 positive regulation of lymphocyte mediated immunity; GO:0032438 melanosome organization; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0043476 pigment accumulation; GO:0045921 positive regulation of exocytosis; GO:0048002 antigen processing and presentation of peptide antigen; GO:0044763 single-organism cellular process; GO:0048757 pigment granule maturation; GO:0048522 positive regulation of cellular process; GO:0051251 positive regulation of lymphocyte activation; GO:1903530 regulation of secretion by cell; GO:0002495 antigen processing and presentation of peptide antigen via MHC class II; GO:0045954 positive regulation of natural killer cell mediated cytotoxicity; GO:0002717 positive regulation of natural killer cell mediated immunity; GO:0051050 positive regulation of transport; GO:0050776 regulation of immune response; GO:0016197 endosomal transport; GO:0006810 transport; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0050865 regulation of cell activation; GO:0050789 regulation of biological process; GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; GO:1903532 positive regulation of secretion by cell; GO:0002705 positive regulation of leukocyte mediated immunity; GO:0048583 regulation of response to stimulus; GO:0042269 regulation of natural killer cell mediated cytotoxicity; GO:0002682 regulation of immune system process; GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II; GO:0051047 positive regulation of secretion; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0032814 regulation of natural killer cell activation; GO:0090160 Golgi to lysosome transport; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0002831 regulation of response to biotic stimulus; GO:0043302 positive regulation of leukocyte degranulation; GO:0031341 regulation of cell killing; GO:0043485 endosome to pigment granule transport; GO:0048066 developmental pigmentation; GO:0048193 Golgi vesicle transport; GO:0017157 regulation of exocytosis; GO:0002715 regulation of natural killer cell mediated immunity; GO:0032816 positive regulation of natural killer cell activation; GO:0080134 regulation of response to stress; GO:0050896 response to stimulus; GO:0050931 pigment cell differentiation; GO:0002706 regulation of lymphocyte mediated immunity; GO:0001912 positive regulation of leukocyte mediated cytotoxicity; GO:0030154 cell differentiation; GO:0050688 regulation of defense response to virus; GO:0050867 positive regulation of cell activation; GO:0031349 positive regulation of defense response; GO:0006886 intracellular protein transport; GO:0043300 regulation of leukocyte degranulation; GO:0043323 positive regulation of natural killer cell degranulation; GO:0016482 cytosolic transport; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0050778 positive regulation of immune response; GO:0006896 Golgi to vacuole transport; GO:0007041 lysosomal transport; GO:0048753 pigment granule organization; GO:0045089 positive regulation of innate immune response; GO:0001910 regulation of leukocyte mediated cytotoxicity; GO:0051049 regulation of transport; GO:0043900 regulation of multi-organism process; GO:0016192 vesicle-mediated transport; GO:0002699 positive regulation of immune effector process; GO:0050792 regulation of viral process; GO:0016050 vesicle organization; GO:0002376 immune system process; GO:0032101 regulation of response to external stimulus; GO:0071702 organic substance transport; GO:1903305 regulation of regulated secretory pathway; GO:0048518 positive regulation of biological process; GO:0035646 endosome to melanosome transport; GO:0051641 cellular localization; GO:0002703 regulation of leukocyte mediated immunity; GO:0045184 establishment of protein localization; GO:0019882 antigen processing and presentation; GO:0002696 positive regulation of leukocyte activation; GO:0070727 cellular macromolecule localization; GO:0044767 single-organism developmental process; GO:0006996 organelle organization; GO:0007034 vacuolar transport; GO:0002684 positive regulation of immune system process; GO:0043473 pigmentation; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0006892 post-Golgi vesicle-mediated transport; GO:0033059 cellular pigmentation; GO:0043482 cellular pigment accumulation; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0030119 AP-type membrane coat adaptor complex; GO:0031090 organelle membrane; GO:0045334 clathrin-coated endocytic vesicle; GO:0031410 cytoplasmic vesicle; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0030669 clathrin-coated endocytic vesicle membrane; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0032588 trans-Golgi network membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0030662 coated vesicle membrane; GO:0055037 recycling endosome; GO:0005765 lysosomal membrane; GO:0030136 clathrin-coated vesicle; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005764 lysosome; GO:0098805 whole membrane; GO:0098791 Golgi subcompartment; GO:0044431 Golgi apparatus part; GO:0005768 endosome; GO:0030139 endocytic vesicle; GO:0043227 membrane-bounded organelle; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0030666 endocytic vesicle membrane; GO:0048475 coated membrane; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0005829 cytosol; GO:0030135 coated vesicle; GO:0030665 clathrin-coated vesicle membrane; GO:0098852 lytic vacuole membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0030131 clathrin adaptor complex; GO:0044437 vacuolar part; GO:0005802 trans-Golgi network; GO:0030118 clathrin coat; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0030117 membrane coat; GO:0005794 Golgi apparatus; GO:0043234 protein complex; GO:0031984 organelle subcompartment; GO:0044444 cytoplasmic part; ","GO:0031267 small GTPase binding; GO:0008092 cytoskeletal protein binding; GO:0008565 protein transporter activity; GO:0030742 GTP-dependent protein binding; GO:0019894 kinesin binding; GO:0017016 Ras GTPase binding; GO:0005488 binding; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0051020 GTPase binding; GO:0019899 enzyme binding; GO:0017137 Rab GTPase binding; GO:0005215 transporter activity; ","K12391","AP1G1; AP-1 complex subunit gamma-1","hsa04142 Lysosome - Homo sapiens (human); ","IPR008152; IPR011989; IPR016024; IPR008153; IPR013041; IPR002553; ","\"Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain; Armadillo-like helical; Armadillo-type fold; Clathrin adaptor, gamma-adaptin, appendage; Coatomer/clathrin adaptor appendage, Ig-like subdomain; Clathrin/coatomer adaptor, adaptin-like, N-terminal; \"\r"]
["O43759","Synaptogyrin-1 OS=Homo sapiens OX=9606 GN=SYNGR1","SYNGR1",25.455,2.9494,5.2,1,1,1,1.106,1.184,1.033,0.857,0.878,0.966,0.813,0.0182,"plasma membrane\r","GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0048172 regulation of short-term neuronal synaptic plasticity; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0051649 establishment of localization in cell; GO:0010646 regulation of cell communication; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0006886 intracellular protein transport; GO:0036230 granulocyte activation; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0048167 regulation of synaptic plasticity; GO:0002443 leukocyte mediated immunity; GO:0050804 modulation of synaptic transmission; GO:0016192 vesicle-mediated transport; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0071702 organic substance transport; GO:0002376 immune system process; GO:0048168 regulation of neuronal synaptic plasticity; GO:0043312 neutrophil degranulation; GO:0002263 cell activation involved in immune response; GO:0002444 myeloid leukocyte mediated immunity; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0002366 leukocyte activation involved in immune response; GO:0006810 transport; GO:0070727 cellular macromolecule localization; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:0050789 regulation of biological process; GO:0032940 secretion by cell; GO:0001775 cell activation; GO:0043299 leukocyte degranulation; GO:0051179 localization; GO:0006955 immune response; GO:0048169 regulation of long-term neuronal synaptic plasticity; GO:0006887 exocytosis; GO:0065007 biological regulation; ","GO:0030658 transport vesicle membrane; GO:0016020 membrane; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0099501 exocytic vesicle membrane; GO:0005623 cell; GO:0043679 axon terminus; GO:0044422 organelle part; GO:0048770 pigment granule; GO:0070382 exocytic vesicle; GO:0005765 lysosomal membrane; GO:0008021 synaptic vesicle; GO:0044425 membrane part; GO:0098793 presynapse; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:0043005 neuron projection; GO:0030141 secretory granule; GO:0044306 neuron projection terminus; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0044456 synapse part; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0042995 cell projection; GO:0098588 bounding membrane of organelle; GO:0031594 neuromuscular junction; GO:0042470 melanosome; GO:0044446 intracellular organelle part; GO:0035577 azurophil granule membrane; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0044463 cell projection part; GO:0030672 synaptic vesicle membrane; GO:0016021 integral component of membrane; GO:0033267 axon part; GO:0005886 plasma membrane; GO:0045202 synapse; GO:0030659 cytoplasmic vesicle membrane; GO:0098852 lytic vacuole membrane; GO:0042582 azurophil granule; GO:0030424 axon; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0030667 secretory granule membrane; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0043195 terminal bouton; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0030133 transport vesicle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR008253; ","Marvel domain; \r"]
["O43765","Small glutamine-rich tetratricopeptide repeat-containing protein alpha OS=Homo sapiens OX=9606 GN=SGTA","SGTA",34.063,14.645,8,2,2,2,0.979,0.955,0.921,0.999,1.059,1.087,1.102,0.0345,"cyto_nucl\r","GO:0032270 positive regulation of cellular protein metabolic process; GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0031331 positive regulation of cellular catabolic process; GO:0044699 single-organism process; GO:0036503 ERAD pathway; GO:0044764 multi-organism cellular process; GO:1905897 regulation of response to endoplasmic reticulum stress; GO:0044237 cellular metabolic process; GO:0031400 negative regulation of protein modification process; GO:1904293 negative regulation of ERAD pathway; GO:0031396 regulation of protein ubiquitination; GO:1903364 positive regulation of cellular protein catabolic process; GO:0008152 metabolic process; GO:0030433 ubiquitin-dependent ERAD pathway; GO:0009893 positive regulation of metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0044419 interspecies interaction between organisms; GO:1903362 regulation of cellular protein catabolic process; GO:1905898 positive regulation of response to endoplasmic reticulum stress; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0031323 regulation of cellular metabolic process; GO:1903363 negative regulation of cellular protein catabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051704 multi-organism process; GO:2000058 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:1901575 organic substance catabolic process; GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0080135 regulation of cellular response to stress; GO:0032269 negative regulation of cellular protein metabolic process; GO:0030163 protein catabolic process; GO:0044710 single-organism metabolic process; GO:0061136 regulation of proteasomal protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0034976 response to endoplasmic reticulum stress; GO:0042177 negative regulation of protein catabolic process; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:1903051 negative regulation of proteolysis involved in cellular protein catabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0010498 proteasomal protein catabolic process; GO:1901799 negative regulation of proteasomal protein catabolic process; GO:0071704 organic substance metabolic process; GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0045862 positive regulation of proteolysis; GO:0016032 viral process; GO:0009896 positive regulation of catabolic process; GO:0044248 cellular catabolic process; GO:0006508 proteolysis; GO:0009895 negative regulation of catabolic process; GO:0042176 regulation of protein catabolic process; GO:0009987 cellular process; GO:0031397 negative regulation of protein ubiquitination; GO:0043632 modification-dependent macromolecule catabolic process; GO:1904292 regulation of ERAD pathway; GO:0044265 cellular macromolecule catabolic process; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0045861 negative regulation of proteolysis; GO:0006950 response to stress; GO:0019941 modification-dependent protein catabolic process; GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process; GO:0044712 single-organism catabolic process; GO:1901800 positive regulation of proteasomal protein catabolic process; GO:0010033 response to organic substance; GO:0048585 negative regulation of response to stimulus; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0009892 negative regulation of metabolic process; GO:1903573 negative regulation of response to endoplasmic reticulum stress; GO:1903321 negative regulation of protein modification by small protein conjugation or removal; GO:0031330 negative regulation of cellular catabolic process; GO:0051247 positive regulation of protein metabolic process; GO:0051246 regulation of protein metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0009057 macromolecule catabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0045732 positive regulation of protein catabolic process; GO:1904294 positive regulation of ERAD pathway; GO:0048584 positive regulation of response to stimulus; GO:0009056 catabolic process; GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process; GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process; GO:0065007 biological regulation; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:1904288 BAT3 complex binding; GO:0005515 protein binding; GO:0043621 protein self-association; GO:0005488 binding; GO:0032403 protein complex binding; GO:0044877 macromolecular complex binding; ","K16365",null,null,"IPR011990; IPR032374; IPR013026; ","\"Tetratricopeptide-like helical domain; SGTA, homodimerisation domain; Tetratricopeptide repeat-containing domain; \"\r"]
["O43772","Mitochondrial carnitine/acylcarnitine carrier protein OS=Homo sapiens OX=9606 GN=SLC25A20","SLC25A20",32.943,4.7666,8.6,3,4,3,0.936,1.223,1.092,0.874,1.1,0.794,0.851,0.255,"plasma membrane\r","GO:0046907 intracellular transport; GO:0034220 ion transmembrane transport; GO:0006839 mitochondrial transport; GO:0044699 single-organism process; GO:0072488 ammonium transmembrane transport; GO:0015838 amino-acid betaine transport; GO:0098656 anion transmembrane transport; GO:0051234 establishment of localization; GO:1902603 carnitine transmembrane transport; GO:0015908 fatty acid transport; GO:0032365 intracellular lipid transport; GO:0051649 establishment of localization in cell; GO:1902578 single-organism localization; GO:0015718 monocarboxylic acid transport; GO:1903825 organic acid transmembrane transport; GO:0006812 cation transport; GO:1990542 mitochondrial transmembrane transport; GO:0006844 acyl carnitine transport; GO:1902580 single-organism cellular localization; GO:0033036 macromolecule localization; GO:0015879 carnitine transport; GO:1905039 carboxylic acid transmembrane transport; GO:0044765 single-organism transport; GO:0006869 lipid transport; GO:0098655 cation transmembrane transport; GO:1902001 fatty acid transmembrane transport; GO:0015696 ammonium transport; GO:0051181 cofactor transport; GO:0010876 lipid localization; GO:0071702 organic substance transport; GO:0046942 carboxylic acid transport; GO:0015849 organic acid transport; GO:1902616 acyl carnitine transmembrane transport; GO:1902582 single-organism intracellular transport; GO:0051641 cellular localization; GO:0015909 long-chain fatty acid transport; GO:0006820 anion transport; GO:0006810 transport; GO:0055085 transmembrane transport; GO:0015711 organic anion transport; GO:0006811 ion transport; GO:0015697 quaternary ammonium group transport; GO:0051179 localization; GO:0071705 nitrogen compound transport; GO:0006853 carnitine shuttle; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044429 mitochondrial part; GO:0031090 organelle membrane; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005740 mitochondrial envelope; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0031975 envelope; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0022804 active transmembrane transporter activity; GO:0015291 secondary active transmembrane transporter activity; GO:0008519 ammonium transmembrane transporter activity; GO:0015226 carnitine transmembrane transporter activity; GO:0015075 ion transmembrane transporter activity; GO:0015199 amino-acid betaine transmembrane transporter activity; GO:0005476 carnitine:acyl carnitine antiporter activity; GO:0022892 substrate-specific transporter activity; GO:0015101 organic cation transmembrane transporter activity; GO:0015297 antiporter activity; GO:0015651 quaternary ammonium group transmembrane transporter activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0072349 modified amino acid transmembrane transporter activity; GO:0015227 acyl carnitine transmembrane transporter activity; GO:0008324 cation transmembrane transporter activity; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; ","K15109","SLC25A20_29; solute carrier family 25 (mitochondrial carnitine/acylcarnitine transporter), member 20/29","hsa04714 Thermogenesis - Homo sapiens (human); ","IPR023395; ","Mitochondrial carrier domain; \r"]
["O43776","Asparagine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=NARS","NARS",62.942,79.82,20.6,11,18,11,0.949,0.968,0.983,1.039,1.051,1.087,1.096,0.00578,"cytoplasm\r","GO:0006518 peptide metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0006421 asparaginyl-tRNA aminoacylation; GO:1901566 organonitrogen compound biosynthetic process; GO:0043039 tRNA aminoacylation; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0006418 tRNA aminoacylation for protein translation; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0006412 translation; GO:0009987 cellular process; GO:0043043 peptide biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0016070 RNA metabolic process; GO:0006399 tRNA metabolic process; GO:0090304 nucleic acid metabolic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0044710 single-organism metabolic process; GO:0043038 amino acid activation; GO:0019752 carboxylic acid metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0006082 organic acid metabolic process; GO:0034660 ncRNA metabolic process; GO:0043436 oxoacid metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds; GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0016875 ligase activity, forming carbon-oxygen bonds; GO:0016874 ligase activity; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0004816 asparagine-tRNA ligase activity; GO:0004812 aminoacyl-tRNA ligase activity; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K01893","NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]","hsa00970 Aminoacyl-tRNA biosynthesis - Homo sapiens (human); ","IPR004364; IPR012340; IPR004365; IPR006195; ","\"Aminoacyl-tRNA synthetase, class II (D/K/N); Nucleic acid-binding, OB-fold; OB-fold nucleic acid binding domain, AA-tRNA synthetase-type; Aminoacyl-tRNA synthetase, class II; \"\r"]
["O43795","Unconventional myosin-Ib OS=Homo sapiens OX=9606 GN=MYO1B","MYO1B",131.98,31.533,8.4,8,9,7,1.018,1.071,1.054,0.953,0.904,1.026,0.917,0.092,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0030048 actin filament-based movement; GO:0016043 cellular component organization; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0048193 Golgi vesicle transport; GO:0007015 actin filament organization; GO:0044699 single-organism process; GO:0051017 actin filament bundle assembly; GO:0051234 establishment of localization; GO:0061572 actin filament bundle organization; GO:0006810 transport; GO:1902589 single-organism organelle organization; GO:0030036 actin cytoskeleton organization; GO:0022607 cellular component assembly; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0006928 movement of cell or subcellular component; GO:0006892 post-Golgi vesicle-mediated transport; GO:0051179 localization; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0097435 supramolecular fiber organization; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0098862 cluster of actin-based cell projections; GO:0005903 brush border; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0098858 actin-based cell projection; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0030175 filopodium; GO:0048471 perinuclear region of cytoplasm; GO:0005884 actin filament; GO:0005768 endosome; GO:0016459 myosin complex; GO:0043227 membrane-bounded organelle; GO:0045177 apical part of cell; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0010008 endosome membrane; GO:0099513 polymeric cytoskeletal fiber; GO:0042995 cell projection; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0015629 actin cytoskeleton; GO:0005576 extracellular region; GO:0099081 supramolecular polymer; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0051015 actin filament binding; GO:0003774 motor activity; GO:1901265 nucleoside phosphate binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0016887 ATPase activity; GO:1902936 phosphatidylinositol bisphosphate binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0008092 cytoskeletal protein binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005546 phosphatidylinositol-4,5-bisphosphate binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0035091 phosphatidylinositol binding; GO:0032550 purine ribonucleoside binding; GO:0008289 lipid binding; GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0000146 microfilament motor activity; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0030898 actin-dependent ATPase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:1901981 phosphatidylinositol phosphate binding; GO:0005524 ATP binding; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0005516 calmodulin binding; GO:0050839 cell adhesion molecule binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0042623 ATPase activity, coupled; GO:0005543 phospholipid binding; GO:0003779 actin binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0032403 protein complex binding; GO:0036094 small molecule binding; ","K10356",null,null,"IPR010926; IPR027417; IPR001609; ","\"Class I myosin tail homology domain; P-loop containing nucleoside triphosphate hydrolase; Myosin head, motor domain; \"\r"]
["O43809","Cleavage and polyadenylation specificity factor subunit 5 OS=Homo sapiens OX=9606 GN=NUDT21","NUDT21",26.227,30.827,24.2,6,7,6,0.895,0.913,0.878,1.12,1.117,1.05,1.224,1.08E-3,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:0031123 RNA 3'-end processing; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0031124 mRNA 3'-end processing; GO:0006378 mRNA polyadenylation; GO:0097659 nucleic acid-templated transcription; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0051259 protein oligomerization; GO:0071704 organic substance metabolic process; GO:0006353 DNA-templated transcription, termination; GO:0000398 mRNA splicing, via spliceosome; GO:0008152 metabolic process; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0051262 protein tetramerization; GO:0022607 cellular component assembly; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0065003 macromolecular complex assembly; GO:0000375 RNA splicing, via transesterification reactions; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0006396 RNA processing; GO:0018130 heterocycle biosynthetic process; GO:0071822 protein complex subunit organization; GO:0043631 RNA polyadenylation; GO:0006369 termination of RNA polymerase II transcription; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0006366 transcription from RNA polymerase II promoter; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0070271 protein complex biogenesis; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0042382 paraspeckles; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0016604 nuclear body; GO:0044422 organelle part; GO:0005849 mRNA cleavage factor complex; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005815 microtubule organizing center; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0005813 centrosome; GO:0044464 cell part; GO:0005622 intracellular; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0003723 RNA binding; GO:0017091 AU-rich element binding; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0003729 mRNA binding; GO:0042826 histone deacetylase binding; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0042803 protein homodimerization activity; GO:0003676 nucleic acid binding; GO:0019899 enzyme binding; ","K14397","NUDT21; cleavage and polyadenylation specificity factor subunit 5","hsa03015 mRNA surveillance pathway - Homo sapiens (human); ","IPR015797; IPR000086; ","NUDIX hydrolase domain-like; NUDIX hydrolase domain; \r"]
["O43813","LanC-like protein 1 OS=Homo sapiens OX=9606 GN=LANCL1","LANCL1",45.283,37.924,21.3,7,9,7,1.088,1.094,1.119,0.907,0.856,0.933,0.817,0.00162,"cytoplasm\r","GO:0007186 G-protein coupled receptor signaling pathway; GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0051716 cellular response to stimulus; GO:0007165 signal transduction; GO:0050789 regulation of biological process; GO:0007154 cell communication; GO:0044699 single-organism process; GO:0023052 signaling; GO:0050896 response to stimulus; GO:0009987 cellular process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0031226 intrinsic component of plasma membrane; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0044459 plasma membrane part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0038023 signaling receptor activity; GO:0005102 receptor binding; GO:0043167 ion binding; GO:0004930 G-protein coupled receptor activity; GO:0005515 protein binding; GO:0033218 amide binding; GO:0043295 glutathione binding; GO:0008270 zinc ion binding; GO:1900750 oligopeptide binding; GO:0004888 transmembrane signaling receptor activity; GO:0017124 SH3 domain binding; GO:1901681 sulfur compound binding; GO:0004871 signal transducer activity; GO:0070325 lipoprotein particle receptor binding; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0072341 modified amino acid binding; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0042277 peptide binding; GO:0005488 binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0019904 protein domain specific binding; GO:0043168 anion binding; GO:0050750 low-density lipoprotein particle receptor binding; GO:0099600 transmembrane receptor activity; ",{"$nulls":3},"IPR012341; ","Six-hairpin glycosidase; \r"]
["O43815","Striatin OS=Homo sapiens OX=9606 GN=STRN","STRN",86.131,43.694,6.9,6,7,6,0.958,0.926,0.975,1.018,1.06,1.079,1.104,0.0124,"nucleus\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0050794 regulation of cellular process; GO:0034329 cell junction assembly; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0016358 dendrite development; GO:0042127 regulation of cell proliferation; GO:0007166 cell surface receptor signaling pathway; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0045216 cell-cell junction organization; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0008285 negative regulation of cell proliferation; GO:0007610 behavior; GO:0007165 signal transduction; GO:0030154 cell differentiation; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0070830 bicellular tight junction assembly; GO:0007275 multicellular organism development; GO:0016055 Wnt signaling pathway; GO:0009987 cellular process; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0043297 apical junction assembly; GO:0051716 cellular response to stimulus; GO:0007043 cell-cell junction assembly; GO:0048731 system development; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0023052 signaling; GO:0031175 neuron projection development; GO:0032501 multicellular organismal process; GO:0198738 cell-cell signaling by wnt; GO:0030182 neuron differentiation; GO:0050789 regulation of biological process; GO:0007267 cell-cell signaling; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0034330 cell junction organization; GO:0030030 cell projection organization; GO:0044767 single-organism developmental process; GO:0007626 locomotory behavior; GO:0048856 anatomical structure development; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0030425 dendrite; GO:0016020 membrane; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0043025 neuronal cell body; GO:0044424 intracellular part; GO:0005911 cell-cell junction; GO:0005623 cell; GO:0032279 asymmetric synapse; GO:0043197 dendritic spine; GO:0070160 occluding junction; GO:0098590 plasma membrane region; GO:0044309 neuron spine; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0014069 postsynaptic density; GO:0097060 synaptic membrane; GO:0043005 neuron projection; GO:0097458 neuron part; GO:0098984 neuron to neuron synapse; GO:0044456 synapse part; GO:0042995 cell projection; GO:0044463 cell projection part; GO:0005923 bicellular tight junction; GO:0043296 apical junction complex; GO:0045202 synapse; GO:0005886 plasma membrane; GO:0045211 postsynaptic membrane; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0098794 postsynapse; GO:0044459 plasma membrane part; GO:0044297 cell body; GO:0099572 postsynaptic specialization; ","GO:0030331 estrogen receptor binding; GO:0070016 armadillo repeat domain binding; GO:0019903 protein phosphatase binding; GO:0005102 receptor binding; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0035257 nuclear hormone receptor binding; GO:0035258 steroid hormone receptor binding; GO:0005515 protein binding; GO:0019904 protein domain specific binding; GO:0019902 phosphatase binding; GO:0051427 hormone receptor binding; GO:0005516 calmodulin binding; GO:0051721 protein phosphatase 2A binding; GO:0019899 enzyme binding; GO:0032403 protein complex binding; ","K17608",null,null,"IPR017986; IPR013258; IPR015943; ","\"WD40-repeat-containing domain; Striatin, N-terminal; WD40/YVTN repeat-like-containing domain; \"\r"]
["O43837","Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=IDH3B","IDH3B",42.183,70.34,28.8,10,15,10,0.92,0.962,0.974,1.001,1.037,1.057,1.084,0.0269,"mitochondria\r","GO:0072350 tricarboxylic acid metabolic process; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006099 tricarboxylic acid cycle; GO:0044699 single-organism process; GO:0006102 isocitrate metabolic process; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0045333 cellular respiration; GO:0071704 organic substance metabolic process; GO:0006101 citrate metabolic process; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0044710 single-organism metabolic process; GO:0009060 aerobic respiration; GO:0015980 energy derivation by oxidation of organic compounds; GO:0019752 carboxylic acid metabolic process; GO:0006082 organic acid metabolic process; GO:0009987 cellular process; GO:0043436 oxoacid metabolic process; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0000287 magnesium ion binding; GO:1901265 nucleoside phosphate binding; GO:0043167 ion binding; GO:0004448 isocitrate dehydrogenase activity; GO:0000166 nucleotide binding; GO:0048037 cofactor binding; GO:0016491 oxidoreductase activity; GO:0009055 electron carrier activity; GO:0016614 oxidoreductase activity, acting on CH-OH group of donors; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; GO:0003824 catalytic activity; GO:0051287 NAD binding; GO:0005488 binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0004449 isocitrate dehydrogenase (NAD+) activity; GO:0036094 small molecule binding; GO:0050662 coenzyme binding; ","K00030","IDH3; isocitrate dehydrogenase (NAD+) [EC:1.1.1.41]","hsa01210 2-Oxocarboxylic acid metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00020 Citrate cycle (TCA cycle) - Homo sapiens (human); hsa01230 Biosynthesis of amino acids - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); ","IPR024084; ","Isopropylmalate dehydrogenase-like domain; \r"]
["O43847","Nardilysin OS=Homo sapiens OX=9606 GN=NRDC","NRDC",131.57,29.019,7,8,11,8,0.888,0.868,0.882,1.19,1.136,1.095,1.297,4.84E-4,"mitochondria\r","GO:0050794 regulation of cellular process; GO:0007528 neuromuscular junction development; GO:0016477 cell migration; GO:0016043 cellular component organization; GO:0032270 positive regulation of cellular protein metabolic process; GO:0051674 localization of cell; GO:0060255 regulation of macromolecule metabolic process; GO:0031331 positive regulation of cellular catabolic process; GO:0044699 single-organism process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0045862 positive regulation of proteolysis; GO:0051044 positive regulation of membrane protein ectodomain proteolysis; GO:0009893 positive regulation of metabolic process; GO:0051043 regulation of membrane protein ectodomain proteolysis; GO:0009896 positive regulation of catabolic process; GO:0006508 proteolysis; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0042176 regulation of protein catabolic process; GO:0009987 cellular process; GO:0052548 regulation of endopeptidase activity; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0008283 cell proliferation; GO:0030162 regulation of proteolysis; GO:0048870 cell motility; GO:0044238 primary metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0048518 positive regulation of biological process; GO:0050808 synapse organization; GO:0051247 positive regulation of protein metabolic process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:0051246 regulation of protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0031325 positive regulation of cellular metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0006928 movement of cell or subcellular component; GO:0045732 positive regulation of protein catabolic process; GO:0040011 locomotion; GO:0052547 regulation of peptidase activity; GO:0051179 localization; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0009986 cell surface; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:0004175 endopeptidase activity; GO:0004222 metalloendopeptidase activity; GO:0008233 peptidase activity; GO:0048408 epidermal growth factor binding; GO:0003824 catalytic activity; GO:0019838 growth factor binding; GO:0042562 hormone binding; GO:0005488 binding; GO:0043167 ion binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0008237 metallopeptidase activity; GO:0005515 protein binding; GO:0016787 hydrolase activity; ","K01411",null,null,"IPR007863; IPR032632; IPR011765; IPR011249; IPR011237; ","\"Peptidase M16, C-terminal; Peptidase M16, middle/third domain; Peptidase M16, N-terminal; Metalloenzyme, LuxS/M16 peptidase-like; Peptidase M16 domain; \"\r"]
["O43852","Calumenin OS=Homo sapiens OX=9606 GN=CALU","CALU",37.106,87.252,38.7,12,21,12,1.069,1.082,1.046,0.955,0.922,0.97,0.891,2.96E-3,"extracellular\r",null,"GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0033018 sarcoplasmic reticulum lumen; GO:0016528 sarcoplasm; GO:0005623 cell; GO:0044422 organelle part; GO:0048770 pigment granule; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0005788 endoplasmic reticulum lumen; GO:0042470 melanosome; GO:0044446 intracellular organelle part; GO:0016529 sarcoplasmic reticulum; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044432 endoplasmic reticulum part; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0005509 calcium ion binding; GO:0005488 binding; GO:0043167 ion binding; ",{"$nulls":3},"IPR011992; IPR002048; ","EF-hand domain pair; EF-hand domain; \r"]
["O43865","S-adenosylhomocysteine hydrolase-like protein 1 OS=Homo sapiens OX=9606 GN=AHCYL1","AHCYL1",58.951,49.144,19.4,10,13,3,1.038,1.071,1.036,0.962,0.936,0.972,0.913,0.0042,"cytoplasm\r","GO:0044700 single organism signaling; GO:0009116 nucleoside metabolic process; GO:1904385 cellular response to angiotensin; GO:0051169 nuclear transport; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0042044 fluid transport; GO:0008152 metabolic process; GO:0046130 purine ribonucleoside catabolic process; GO:0032879 regulation of localization; GO:0031440 regulation of mRNA 3'-end processing; GO:0044057 regulation of system process; GO:0009719 response to endogenous stimulus; GO:0006555 methionine metabolic process; GO:0043170 macromolecule metabolic process; GO:0008104 protein localization; GO:1901652 response to peptide; GO:0044765 single-organism transport; GO:0006790 sulfur compound metabolic process; GO:0006396 RNA processing; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0043269 regulation of ion transport; GO:0072521 purine-containing compound metabolic process; GO:0050684 regulation of mRNA processing; GO:0006732 coenzyme metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0006611 protein export from nucleus; GO:0034762 regulation of transmembrane transport; GO:0046395 carboxylic acid catabolic process; GO:1903779 regulation of cardiac conduction; GO:0006810 transport; GO:0019439 aromatic compound catabolic process; GO:1901575 organic substance catabolic process; GO:0010243 response to organonitrogen compound; GO:0006152 purine nucleoside catabolic process; GO:0044710 single-organism metabolic process; GO:1901698 response to nitrogen compound; GO:0044260 cellular macromolecule metabolic process; GO:0009063 cellular amino acid catabolic process; GO:0006913 nucleocytoplasmic transport; GO:0032412 regulation of ion transmembrane transporter activity; GO:0016071 mRNA metabolic process; GO:0043436 oxoacid metabolic process; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0002028 regulation of sodium ion transport; GO:0006378 mRNA polyadenylation; GO:1901700 response to oxygen-containing compound; GO:0009066 aspartate family amino acid metabolic process; GO:0072523 purine-containing compound catabolic process; GO:0051239 regulation of multicellular organismal process; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:1902578 single-organism localization; GO:0006139 nucleobase-containing compound metabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0010959 regulation of metal ion transport; GO:0044248 cellular catabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0034613 cellular protein localization; GO:0009119 ribonucleoside metabolic process; GO:0032409 regulation of transporter activity; GO:1901658 glycosyl compound catabolic process; GO:1901136 carbohydrate derivative catabolic process; GO:0042045 epithelial fluid transport; GO:0071702 organic substance transport; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901605 alpha-amino acid metabolic process; GO:0046439 L-cysteine metabolic process; GO:0045184 establishment of protein localization; GO:0007186 G-protein coupled receptor signaling pathway; GO:0043270 positive regulation of ion transport; GO:1903311 regulation of mRNA metabolic process; GO:0016054 organic acid catabolic process; GO:0009164 nucleoside catabolic process; GO:0051179 localization; GO:1901564 organonitrogen compound metabolic process; GO:1901606 alpha-amino acid catabolic process; GO:0042278 purine nucleoside metabolic process; GO:0046498 S-adenosylhomocysteine metabolic process; GO:0044070 regulation of anion transport; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0051168 nuclear export; GO:0000096 sulfur amino acid metabolic process; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:0006520 cellular amino acid metabolic process; GO:0051649 establishment of localization in cell; GO:1901653 cellular response to peptide; GO:0007154 cell communication; GO:0070633 transepithelial transport; GO:0010765 positive regulation of sodium ion transport; GO:0006534 cysteine metabolic process; GO:1901361 organic cyclic compound catabolic process; GO:0010035 response to inorganic substance; GO:0033036 macromolecule localization; GO:0070887 cellular response to chemical stimulus; GO:0010468 regulation of gene expression; GO:0043631 RNA polyadenylation; GO:0046500 S-adenosylmethionine metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0038166 angiotensin-activated signaling pathway; GO:0022898 regulation of transmembrane transporter activity; GO:0023052 signaling; GO:0010038 response to metal ion; GO:0051050 positive regulation of transport; GO:0051186 cofactor metabolic process; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:0071417 cellular response to organonitrogen compound; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0090304 nucleic acid metabolic process; GO:0009069 serine family amino acid metabolic process; GO:0043434 response to peptide hormone; GO:1901699 cellular response to nitrogen compound; GO:0032870 cellular response to hormone stimulus; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0044273 sulfur compound catabolic process; GO:1901657 glycosyl compound metabolic process; GO:0006082 organic acid metabolic process; GO:0031123 RNA 3'-end processing; GO:0006725 cellular aromatic compound metabolic process; GO:0031124 mRNA 3'-end processing; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0071310 cellular response to organic substance; GO:1903522 regulation of blood circulation; GO:0033353 S-adenosylmethionine cycle; GO:0008016 regulation of heart contraction; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0042454 ribonucleoside catabolic process; GO:0006730 one-carbon metabolic process; GO:0071375 cellular response to peptide hormone stimulus; GO:0006886 intracellular protein transport; GO:0051592 response to calcium ion; GO:0034641 cellular nitrogen compound metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0051049 regulation of transport; GO:0044712 single-organism catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044282 small molecule catabolic process; GO:1990776 response to angiotensin; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0019510 S-adenosylhomocysteine catabolic process; GO:0046128 purine ribonucleoside metabolic process; GO:0070727 cellular macromolecule localization; GO:1901565 organonitrogen compound catabolic process; GO:1901701 cellular response to oxygen-containing compound; GO:0034765 regulation of ion transmembrane transport; GO:0071495 cellular response to endogenous stimulus; GO:0019752 carboxylic acid metabolic process; GO:0010467 gene expression; GO:0009725 response to hormone; GO:0009056 catabolic process; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0016324 apical plasma membrane; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0098590 plasma membrane region; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0045177 apical part of cell; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044459 plasma membrane part; GO:0044432 endoplasmic reticulum part; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0003723 RNA binding; GO:0016801 hydrolase activity, acting on ether bonds; GO:1901265 nucleoside phosphate binding; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0048037 cofactor binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0004013 adenosylhomocysteinase activity; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0051287 NAD binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0016802 trialkylsulfonium hydrolase activity; GO:0036094 small molecule binding; GO:0050662 coenzyme binding; ","K01251","E3.3.1.1; adenosylhomocysteinase [EC:3.3.1.1]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00270 Cysteine and methionine metabolism - Homo sapiens (human); ","IPR016040; IPR015878; ","\"NAD(P)-binding domain; S-adenosyl-L-homocysteine hydrolase, NAD binding domain; \"\r"]
["O43866","CD5 antigen-like OS=Homo sapiens OX=9606 GN=CD5L","CD5L",38.087,82.323,45.2,10,12,10,1.066,1.042,1.012,0.905,0.958,0.915,0.89,7.26E-3,"extracellular\r","GO:0006950 response to stress; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0002376 immune system process; GO:0006897 endocytosis; GO:0050896 response to stimulus; GO:0051234 establishment of localization; GO:0006810 transport; GO:0008219 cell death; GO:0006968 cellular defense response; GO:0006954 inflammatory response; GO:0006915 apoptotic process; GO:0012501 programmed cell death; GO:0006952 defense response; GO:0006898 receptor-mediated endocytosis; GO:0051179 localization; GO:0009987 cellular process; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0072562 blood microparticle; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0038024 cargo receptor activity; GO:0005044 scavenger receptor activity; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; ",{"$nulls":3},"IPR001190; IPR017448; ","SRCR domain; SRCR-like domain; \r"]
["O43920","NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 OS=Homo sapiens OX=9606 GN=NDUFS5","NDUFS5",12.517,24.026,45.3,5,7,5,1.018,1.01,1.069,1.017,0.883,0.995,0.935,0.219,"extracellular\r","GO:0044085 cellular component biogenesis; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0022607 cellular component assembly; GO:0006753 nucleoside phosphate metabolic process; GO:0065003 macromolecular complex assembly; GO:0007005 mitochondrion organization; GO:0019693 ribose phosphate metabolic process; GO:0071822 protein complex subunit organization; GO:0010257 NADH dehydrogenase complex assembly; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0006119 oxidative phosphorylation; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0006120 mitochondrial electron transport, NADH to ubiquinone; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0097031 mitochondrial respiratory chain complex I biogenesis; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0022900 electron transport chain; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0070271 protein complex biogenesis; GO:0033108 mitochondrial respiratory chain complex assembly; GO:0016043 cellular component organization; GO:0016310 phosphorylation; GO:0006725 cellular aromatic compound metabolic process; GO:0042773 ATP synthesis coupled electron transport; GO:0009259 ribonucleotide metabolic process; GO:0022904 respiratory electron transport chain; GO:0071704 organic substance metabolic process; GO:0032981 mitochondrial respiratory chain complex I assembly; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0009119 ribonucleoside metabolic process; GO:0006461 protein complex assembly; GO:0043623 cellular protein complex assembly; GO:0046034 ATP metabolic process; GO:0034622 cellular macromolecular complex assembly; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0045333 cellular respiration; GO:0006163 purine nucleotide metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0046128 purine ribonucleoside metabolic process; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:1901564 organonitrogen compound metabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0045271 respiratory chain complex I; GO:0032991 macromolecular complex; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0005747 mitochondrial respiratory chain complex I; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0031970 organelle envelope lumen; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0098803 respiratory chain complex; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005739 mitochondrion; GO:0005746 mitochondrial respiratory chain; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0030964 NADH dehydrogenase complex; GO:0005758 mitochondrial intermembrane space; GO:1990204 oxidoreductase complex; GO:0031975 envelope; GO:0043234 protein complex; GO:0031966 mitochondrial membrane; GO:0070469 respiratory chain; GO:0044444 cytoplasmic part; ","GO:0050136 NADH dehydrogenase (quinone) activity; GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:0003954 NADH dehydrogenase activity; GO:0003824 catalytic activity; GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; GO:0008137 NADH dehydrogenase (ubiquinone) activity; GO:0016491 oxidoreductase activity; ","K03938","NDUFS5; NADH dehydrogenase (ubiquinone) Fe-S protein 5","hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); "]
["O60216","Double-strand-break repair protein rad21 homolog OS=Homo sapiens OX=9606 GN=RAD21","RAD21",71.689,9.9779,6,4,4,4,0.877,0.909,0.979,1.091,1.039,1.101,1.169,0.0135,"cytoplasm\r","GO:0022414 reproductive process; GO:0097659 nucleic acid-templated transcription; GO:0007067 mitotic nuclear division; GO:0009891 positive regulation of biosynthetic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0007131 reciprocal meiotic recombination; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0051130 positive regulation of cellular component organization; GO:2001141 regulation of RNA biosynthetic process; GO:0000819 sister chromatid segregation; GO:0008152 metabolic process; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0006915 apoptotic process; GO:0044702 single organism reproductive process; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0033365 protein localization to organelle; GO:0043170 macromolecule metabolic process; GO:0090068 positive regulation of cell cycle process; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0051726 regulation of cell cycle; GO:0006310 DNA recombination; GO:0010468 regulation of gene expression; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0033045 regulation of sister chromatid segregation; GO:0018130 heterocycle biosynthetic process; GO:0007059 chromosome segregation; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0051321 meiotic cell cycle; GO:0035825 reciprocal DNA recombination; GO:0031323 regulation of cellular metabolic process; GO:0016070 RNA metabolic process; GO:1902589 single-organism organelle organization; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0010638 positive regulation of organelle organization; GO:0006351 transcription, DNA-templated; GO:2001252 positive regulation of chromosome organization; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0051301 cell division; GO:0045876 positive regulation of sister chromatid cohesion; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0034502 protein localization to chromosome; GO:0050794 regulation of cellular process; GO:0000003 reproduction; GO:0016043 cellular component organization; GO:0033554 cellular response to stress; GO:1903046 meiotic cell cycle process; GO:0006725 cellular aromatic compound metabolic process; GO:0006259 DNA metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0048285 organelle fission; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0006302 double-strand break repair; GO:0050896 response to stimulus; GO:1903047 mitotic cell cycle process; GO:0071704 organic substance metabolic process; GO:0007127 meiosis I; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0051984 positive regulation of chromosome segregation; GO:0009059 macromolecule biosynthetic process; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0045787 positive regulation of cell cycle; GO:0051983 regulation of chromosome segregation; GO:0051254 positive regulation of RNA metabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0006950 response to stress; GO:0007063 regulation of sister chromatid cohesion; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0033043 regulation of organelle organization; GO:0006807 nitrogen compound metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:1901576 organic substance biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0033044 regulation of chromosome organization; GO:0044249 cellular biosynthetic process; GO:0006974 cellular response to DNA damage stimulus; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0051641 cellular localization; GO:0071168 protein localization to chromatin; GO:0070727 cellular macromolecule localization; GO:0006281 DNA repair; GO:0051276 chromosome organization; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0008219 cell death; GO:0098813 nuclear chromosome segregation; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0006366 transcription from RNA polymerase II promoter; GO:0000280 nuclear division; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0010467 gene expression; GO:0007126 meiotic nuclear division; GO:0051128 regulation of cellular component organization; GO:0007062 sister chromatid cohesion; GO:0012501 programmed cell death; GO:0022402 cell cycle process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0051179 localization; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0000793 condensed chromosome; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0044454 nuclear chromosome part; GO:0005694 chromosome; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0000798 nuclear cohesin complex; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0008278 cohesin complex; GO:0098687 chromosomal region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0000785 chromatin; GO:0000775 chromosome, centromeric region; GO:0000228 nuclear chromosome; GO:0000794 condensed nuclear chromosome; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding; GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding; GO:0005515 protein binding; GO:0003682 chromatin binding; GO:0005488 binding; GO:0003700 transcription factor activity, sequence-specific DNA binding; GO:0001071 nucleic acid binding transcription factor activity; ","K06670","SCC1; cohesin complex subunit SCC1","hsa04110 Cell cycle - Homo sapiens (human); ","IPR006909; IPR011991; IPR023093; IPR006910; ","\"Rad21/Rec8-like protein, C-terminal, eukaryotic; Winged helix-turn-helix DNA-binding domain; Rad21/Rec8-like protein, C-terminal; Rad21/Rec8-like protein, N-terminal; \"\r"]
["O60218","Aldo-keto reductase family 1 member B10 OS=Homo sapiens OX=9606 GN=AKR1B10","AKR1B10",36.019,76.037,33.2,10,14,8,0.615,0.664,0.623,1.344,1.423,1.33,2.154,1.86e-05,"cytoplasm\r","GO:0044707 single-multicellular organism process; GO:0007586 digestion; GO:1901615 organic hydroxy compound metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0006066 alcohol metabolic process; GO:0016095 polyprenol catabolic process; GO:0097164 ammonium ion metabolic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0016107 sesquiterpenoid catabolic process; GO:0046164 alcohol catabolic process; GO:0016115 terpenoid catabolic process; GO:0030638 polyketide metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:1901616 organic hydroxy compound catabolic process; GO:0016488 farnesol catabolic process; GO:0006714 sesquiterpenoid metabolic process; GO:0042180 cellular ketone metabolic process; GO:0001523 retinoid metabolic process; GO:0044248 cellular catabolic process; GO:0016487 farnesol metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0008300 isoprenoid catabolic process; GO:0034308 primary alcohol metabolic process; GO:0016137 glycoside metabolic process; GO:0009987 cellular process; GO:0006629 lipid metabolic process; GO:0019748 secondary metabolic process; GO:0016042 lipid catabolic process; GO:0006720 isoprenoid metabolic process; GO:0044712 single-organism catabolic process; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:1901661 quinone metabolic process; GO:0044597 daunorubicin metabolic process; GO:0044763 single-organism cellular process; GO:0008202 steroid metabolic process; GO:0034310 primary alcohol catabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0006081 cellular aldehyde metabolic process; GO:0044282 small molecule catabolic process; GO:0030647 aminoglycoside antibiotic metabolic process; GO:0044238 primary metabolic process; GO:0032501 multicellular organismal process; GO:0051186 cofactor metabolic process; GO:0016093 polyprenol metabolic process; GO:1901575 organic substance catabolic process; GO:0044598 doxorubicin metabolic process; GO:0044710 single-organism metabolic process; GO:0044242 cellular lipid catabolic process; GO:0016101 diterpenoid metabolic process; GO:0006721 terpenoid metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0009056 catabolic process; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0005773 vacuole; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0000323 lytic vacuole; ","GO:0016614 oxidoreductase activity, acting on CH-OH group of donors; GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors; GO:0047718 indanol dehydrogenase activity; GO:0005515 protein binding; GO:0001758 retinal dehydrogenase activity; GO:0004033 aldo-keto reductase (NADP) activity; GO:0045550 geranylgeranyl reductase activity; GO:0016491 oxidoreductase activity; ","K00011","AKR1B; aldehyde reductase [EC:1.1.1.21]","hsa00051 Fructose and mannose metabolism - Homo sapiens (human); hsa00790 Folate biosynthesis - Homo sapiens (human); hsa00040 Pentose and glucuronate interconversions - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00052 Galactose metabolism - Homo sapiens (human); hsa00561 Glycerolipid metabolism - Homo sapiens (human); ","IPR023210; ","NADP-dependent oxidoreductase domain; \r"]
["O60220","Mitochondrial import inner membrane translocase subunit Tim8 A OS=Homo sapiens OX=9606 GN=TIMM8A","TIMM8A",10.998,28.87,38.1,3,5,3,1.036,1.112,0.874,1.087,0.986,0.996,1.016,0.815,"extracellular\r","GO:0007399 nervous system development; GO:0032502 developmental process; GO:0044707 single-multicellular organism process; GO:0048731 system development; GO:0044699 single-organism process; GO:0071702 organic substance transport; GO:0032501 multicellular organismal process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006810 transport; GO:0045184 establishment of protein localization; GO:1902578 single-organism localization; GO:0044767 single-organism developmental process; GO:0007275 multicellular organism development; GO:0008104 protein localization; GO:0051179 localization; GO:0033036 macromolecule localization; GO:0048856 anatomical structure development; GO:0072321 chaperone-mediated protein transport; GO:0044765 single-organism transport; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044429 mitochondrial part; GO:0031090 organelle membrane; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0031970 organelle envelope lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0005758 mitochondrial intermembrane space; GO:0031975 envelope; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0031966 mitochondrial membrane; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; ","GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0005488 binding; GO:0043167 ion binding; ","K17780",null,null,"IPR004217; ","Tim10/DDP family zinc finger; \r"]
["O60240","Perilipin-1 OS=Homo sapiens OX=9606 GN=PLIN1","PLIN1",55.99,279.88,54,22,46,22,1.106,1.078,1.115,0.907,0.866,0.886,0.806,0.000216,"nucleus\r","GO:0016042 lipid catabolic process; GO:1901575 organic substance catabolic process; GO:0008152 metabolic process; GO:0044710 single-organism metabolic process; GO:0044712 single-organism catabolic process; GO:0044699 single-organism process; GO:0044238 primary metabolic process; GO:0009056 catabolic process; GO:0071704 organic substance metabolic process; GO:0006629 lipid metabolic process; ","GO:0043229 intracellular organelle; GO:0005783 endoplasmic reticulum; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005737 cytoplasm; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0043228 non-membrane-bounded organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0005811 lipid particle; GO:0044444 cytoplasmic part; ","GO:0008289 lipid binding; GO:0005488 binding; ","K08768","PLIN1; perilipin-1","hsa04923 Regulation of lipolysis in adipocytes - Homo sapiens (human); hsa03320 PPAR signaling pathway - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa04371 Apelin signaling pathway - Homo sapiens (human); "]
["O60245","Protocadherin-7 OS=Homo sapiens OX=9606 GN=PCDH7","PCDH7",116.07,4.0463,1.5,1,1,1,0.891,0.903,0.937,1.117,1.087,1.062,1.196,0.00104,"plasma membrane\r","GO:0016192 vesicle-mediated transport; GO:0098609 cell-cell adhesion; GO:0044763 single-organism cellular process; GO:0002576 platelet degranulation; GO:0044699 single-organism process; GO:0051234 establishment of localization; GO:0006810 transport; GO:0022610 biological adhesion; GO:0045055 regulated exocytosis; GO:1902578 single-organism localization; GO:0032940 secretion by cell; GO:0007155 cell adhesion; GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules; GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules; GO:0051179 localization; GO:0009987 cellular process; GO:0006887 exocytosis; GO:0046903 secretion; GO:0044765 single-organism transport; ","GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0016020 membrane; GO:0031226 intrinsic component of plasma membrane; GO:0098588 bounding membrane of organelle; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044433 cytoplasmic vesicle part; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0030667 secretory granule membrane; GO:0044459 plasma membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0099503 secretory vesicle; GO:0030141 secretory granule; GO:0031091 platelet alpha granule; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0031092 platelet alpha granule membrane; ","GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005509 calcium ion binding; GO:0005488 binding; GO:0043167 ion binding; ","K16498",null,null,"IPR015919; IPR013164; IPR013585; IPR002126; ","\"Cadherin-like; Cadherin, N-terminal; Protocadherin; Cadherin; \"\r"]
["O60259","Kallikrein-8 OS=Homo sapiens OX=9606 GN=KLK8","KLK8",28.048,2.1112,5,1,1,1,0.881,0.924,0.843,1.248,0.996,1.109,1.266,0.0297,"extracellular\r","GO:0051093 negative regulation of developmental process; GO:0065008 regulation of biological quality; GO:0043616 keratinocyte proliferation; GO:0031424 keratinization; GO:0051129 negative regulation of cellular component organization; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0051241 negative regulation of multicellular organismal process; GO:0032989 cellular component morphogenesis; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0050877 neurological system process; GO:0050807 regulation of synapse organization; GO:0007610 behavior; GO:0009611 response to wounding; GO:0009913 epidermal cell differentiation; GO:0008152 metabolic process; GO:0032990 cell part morphogenesis; GO:0032102 negative regulation of response to external stimulus; GO:0031644 regulation of neurological system process; GO:0044057 regulation of system process; GO:0048858 cell projection morphogenesis; GO:0008544 epidermis development; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0045596 negative regulation of cell differentiation; GO:0070570 regulation of neuron projection regeneration; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0060429 epithelium development; GO:0043588 skin development; GO:0009888 tissue development; GO:0030216 keratinocyte differentiation; GO:0048699 generation of neurons; GO:0070268 cornification; GO:0044763 single-organism cellular process; GO:0048812 neuron projection morphogenesis; GO:0032501 multicellular organismal process; GO:1903035 negative regulation of response to wounding; GO:0031642 negative regulation of myelination; GO:0050768 negative regulation of neurogenesis; GO:0000902 cell morphogenesis; GO:0050673 epithelial cell proliferation; GO:0048681 negative regulation of axon regeneration; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0080135 regulation of cellular response to stress; GO:0045664 regulation of neuron differentiation; GO:0030030 cell projection organization; GO:0048583 regulation of response to stimulus; GO:0045665 negative regulation of neuron differentiation; GO:0007613 memory; GO:0010721 negative regulation of cell development; GO:0048856 anatomical structure development; GO:0044708 single-organism behavior; GO:0010975 regulation of neuron projection development; GO:2000026 regulation of multicellular organismal development; GO:0030855 epithelial cell differentiation; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0031641 regulation of myelination; GO:0031344 regulation of cell projection organization; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0051239 regulation of multicellular organismal process; GO:0071704 organic substance metabolic process; GO:0070571 negative regulation of neuron projection regeneration; GO:0009653 anatomical structure morphogenesis; GO:0030154 cell differentiation; GO:0051961 negative regulation of nervous system development; GO:0050890 cognition; GO:0031345 negative regulation of cell projection organization; GO:0006508 proteolysis; GO:0007275 multicellular organism development; GO:0048679 regulation of axon regeneration; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0050803 regulation of synapse structure or activity; GO:0003008 system process; GO:0006950 response to stress; GO:0048731 system development; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0032101 regulation of response to external stimulus; GO:0010977 negative regulation of neuron projection development; GO:0008283 cell proliferation; GO:0048585 negative regulation of response to stimulus; GO:0044238 primary metabolic process; GO:0031175 neuron projection development; GO:0050808 synapse organization; GO:0007611 learning or memory; GO:0030182 neuron differentiation; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0031645 negative regulation of neurological system process; GO:0051128 regulation of cellular component organization; GO:0012501 programmed cell death; GO:1903034 regulation of response to wounding; GO:0050793 regulation of developmental process; GO:0050767 regulation of neurogenesis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; ","GO:0004252 serine-type endopeptidase activity; GO:0004175 endopeptidase activity; GO:0008233 peptidase activity; GO:0017171 serine hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0008236 serine-type peptidase activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0016787 hydrolase activity; GO:0005515 protein binding; ","K08650",null,null,"IPR009003; IPR001254; ","\"Peptidase S1, PA clan; Serine proteases, trypsin domain; \"\r"]
["O60271","C-Jun-amino-terminal kinase-interacting protein 4 OS=Homo sapiens OX=9606 GN=SPAG9","SPAG9",146.2,85.747,10.4,11,12,11,0.998,0.998,1.017,0.982,1.034,0.989,0.997,0.876,"endoplasmic reticulum\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0032872 regulation of stress-activated MAPK cascade; GO:0030335 positive regulation of cell migration; GO:0032270 positive regulation of cellular protein metabolic process; GO:0022414 reproductive process; GO:0043506 regulation of JUN kinase activity; GO:0032091 negative regulation of protein binding; GO:0044237 cellular metabolic process; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0065003 macromolecular complex assembly; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0044702 single organism reproductive process; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0051347 positive regulation of transferase activity; GO:0051147 regulation of muscle cell differentiation; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0019953 sexual reproduction; GO:0044763 single-organism cellular process; GO:0051272 positive regulation of cellular component movement; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0000165 MAPK cascade; GO:0080135 regulation of cellular response to stress; GO:0042147 retrograde transport, endosome to Golgi; GO:0032874 positive regulation of stress-activated MAPK cascade; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0051149 positive regulation of muscle cell differentiation; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0048609 multicellular organismal reproductive process; GO:0051094 positive regulation of developmental process; GO:0050794 regulation of cellular process; GO:0000003 reproduction; GO:0016310 phosphorylation; GO:0033554 cellular response to stress; GO:0046907 intracellular transport; GO:0044707 single-multicellular organism process; GO:0051260 protein homooligomerization; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0080134 regulation of response to stress; GO:0071902 positive regulation of protein serine/threonine kinase activity; GO:2000147 positive regulation of cell motility; GO:0045597 positive regulation of cell differentiation; GO:0051239 regulation of multicellular organismal process; GO:0051259 protein oligomerization; GO:0032147 activation of protein kinase activity; GO:2000145 regulation of cell motility; GO:0051338 regulation of transferase activity; GO:0061061 muscle structure development; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:0006461 protein complex assembly; GO:0023014 signal transduction by protein phosphorylation; GO:1902531 regulation of intracellular signal transduction; GO:0006950 response to stress; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0007283 spermatogenesis; GO:0016192 vesicle-mediated transport; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0030334 regulation of cell migration; GO:0043496 regulation of protein homodimerization activity; GO:0044238 primary metabolic process; GO:0051247 positive regulation of protein metabolic process; GO:0043406 positive regulation of MAP kinase activity; GO:0006793 phosphorus metabolic process; GO:0090074 negative regulation of protein homodimerization activity; GO:0031325 positive regulation of cellular metabolic process; GO:0050769 positive regulation of neurogenesis; GO:0043412 macromolecule modification; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:0050793 regulation of developmental process; GO:0046330 positive regulation of JNK cascade; GO:0045666 positive regulation of neuron differentiation; GO:0040017 positive regulation of locomotion; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0006796 phosphate-containing compound metabolic process; GO:0031098 stress-activated protein kinase signaling cascade; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:0070302 regulation of stress-activated protein kinase signaling cascade; GO:0010646 regulation of cell communication; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0009893 positive regulation of metabolic process; GO:0070304 positive regulation of stress-activated protein kinase signaling cascade; GO:0010720 positive regulation of cell development; GO:0033674 positive regulation of kinase activity; GO:0046328 regulation of JNK cascade; GO:0032502 developmental process; GO:0071822 protein complex subunit organization; GO:0045937 positive regulation of phosphate metabolic process; GO:0051098 regulation of binding; GO:0051962 positive regulation of nervous system development; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0016197 endosomal transport; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0051100 negative regulation of binding; GO:0045664 regulation of neuron differentiation; GO:0043507 positive regulation of JUN kinase activity; GO:0007254 JNK cascade; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0036211 protein modification process; GO:0070271 protein complex biogenesis; GO:0048856 anatomical structure development; GO:0043549 regulation of kinase activity; GO:2000026 regulation of multicellular organismal development; GO:0045859 regulation of protein kinase activity; GO:0016043 cellular component organization; GO:0043405 regulation of MAP kinase activity; GO:0060255 regulation of macromolecule metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0043393 regulation of protein binding; GO:0030154 cell differentiation; GO:0006468 protein phosphorylation; GO:0043408 regulation of MAPK cascade; GO:0023056 positive regulation of signaling; GO:0007257 activation of JUN kinase activity; GO:0010647 positive regulation of cell communication; GO:0016482 cytosolic transport; GO:0009987 cellular process; GO:0051403 stress-activated MAPK cascade; GO:0045595 regulation of cell differentiation; GO:0051146 striated muscle cell differentiation; GO:0048232 male gamete generation; GO:0035556 intracellular signal transduction; GO:0001932 regulation of protein phosphorylation; GO:0031401 positive regulation of protein modification process; GO:0001934 positive regulation of protein phosphorylation; GO:0045860 positive regulation of protein kinase activity; GO:0048518 positive regulation of biological process; GO:0007276 gamete generation; GO:0043933 macromolecular complex subunit organization; GO:0043085 positive regulation of catalytic activity; GO:0051641 cellular localization; GO:0032504 multicellular organism reproduction; GO:0000187 activation of MAPK activity; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0044703 multi-organism reproductive process; GO:0042692 muscle cell differentiation; GO:0009967 positive regulation of signal transduction; GO:0040012 regulation of locomotion; GO:0043410 positive regulation of MAPK cascade; GO:0071840 cellular component organization or biogenesis; GO:0050767 regulation of neurogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0005815 microtubule organizing center; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0043226 organelle; GO:0001669 acrosomal vesicle; GO:0097223 sperm part; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005078 MAP-kinase scaffold activity; GO:0019901 protein kinase binding; GO:0051019 mitogen-activated protein kinase binding; GO:0005515 protein binding; GO:0019900 kinase binding; GO:0032947 protein complex scaffold; GO:0008092 cytoskeletal protein binding; GO:0035591 signaling adaptor activity; GO:0008432 JUN kinase binding; GO:0019894 kinesin binding; GO:0005488 binding; GO:0048273 mitogen-activated protein kinase p38 binding; GO:0030159 receptor signaling complex scaffold activity; GO:0060090 binding, bridging; GO:0005198 structural molecule activity; GO:0019899 enzyme binding; ","K20317",null,null,"IPR019143; IPR032486; IPR017986; IPR015943; ","\"JNK/Rab-associated protein-1, N-terminal; JNK-interacting protein, leucine zipper II; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain; \"\r"]
["O60313","Dynamin-like 120 kDa protein, mitochondrial OS=Homo sapiens OX=9606 GN=OPA1","OPA1",111.63,98.49,22.5,19,29,19,0.994,1.037,1.008,0.971,0.963,0.997,0.964,0.0905,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:0010941 regulation of cell death; GO:0007601 visual perception; GO:0090201 negative regulation of release of cytochrome c from mitochondria; GO:0032989 cellular component morphogenesis; GO:1905897 regulation of response to endoplasmic reticulum stress; GO:0010821 regulation of mitochondrion organization; GO:0050877 neurological system process; GO:0010636 positive regulation of mitochondrial fusion; GO:0051240 positive regulation of multicellular organismal process; GO:0065003 macromolecular complex assembly; GO:0044801 single-organism membrane fusion; GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway; GO:0044765 single-organism transport; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0048699 generation of neurons; GO:0031346 positive regulation of cell projection organization; GO:0044763 single-organism cellular process; GO:0061025 membrane fusion; GO:0090398 cellular senescence; GO:0032501 multicellular organismal process; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0007007 inner mitochondrial membrane organization; GO:0006810 transport; GO:0034643 establishment of mitochondrion localization, microtubule-mediated; GO:0007569 cell aging; GO:1902532 negative regulation of intracellular signal transduction; GO:0080135 regulation of cellular response to stress; GO:0048583 regulation of response to stimulus; GO:0060999 positive regulation of dendritic spine development; GO:0051094 positive regulation of developmental process; GO:0060548 negative regulation of cell death; GO:0010975 regulation of neuron projection development; GO:0051640 organelle localization; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0046907 intracellular transport; GO:0044707 single-multicellular organism process; GO:0007006 mitochondrial membrane organization; GO:1903431 positive regulation of cell maturation; GO:0043067 regulation of programmed cell death; GO:0090148 membrane fission; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0070584 mitochondrion morphogenesis; GO:0030705 cytoskeleton-dependent intracellular transport; GO:0048814 regulation of dendrite morphogenesis; GO:0045597 positive regulation of cell differentiation; GO:0051239 regulation of multicellular organismal process; GO:0009653 anatomical structure morphogenesis; GO:1900006 positive regulation of dendrite development; GO:0051646 mitochondrion localization; GO:0023057 negative regulation of signaling; GO:1902578 single-organism localization; GO:0010648 negative regulation of cell communication; GO:0051654 establishment of mitochondrion localization; GO:0003374 dynamin family protein polymerization involved in mitochondrial fission; GO:1902580 single-organism cellular localization; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:0006461 protein complex assembly; GO:0010635 regulation of mitochondrial fusion; GO:0010823 negative regulation of mitochondrion organization; GO:1902531 regulation of intracellular signal transduction; GO:0006950 response to stress; GO:0048731 system development; GO:0098930 axonal transport; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0048284 organelle fusion; GO:0051656 establishment of organelle localization; GO:0007017 microtubule-based process; GO:0014041 regulation of neuron maturation; GO:1903573 negative regulation of response to endoplasmic reticulum stress; GO:0010976 positive regulation of neuron projection development; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0006928 movement of cell or subcellular component; GO:0050769 positive regulation of neurogenesis; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:0012501 programmed cell death; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0048312 intracellular distribution of mitochondria; GO:0045666 positive regulation of neuron differentiation; GO:0009968 negative regulation of signal transduction; GO:0090199 regulation of release of cytochrome c from mitochondria; GO:0023051 regulation of signaling; GO:0051129 negative regulation of cellular component organization; GO:0048869 cellular developmental process; GO:1903429 regulation of cell maturation; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:2001233 regulation of apoptotic signaling pathway; GO:0010970 transport along microtubule; GO:0047497 mitochondrion transport along microtubule; GO:0051649 establishment of localization in cell; GO:0010646 regulation of cell communication; GO:2001243 negative regulation of intrinsic apoptotic signaling pathway; GO:0032990 cell part morphogenesis; GO:0022607 cellular component assembly; GO:0007005 mitochondrion organization; GO:0006915 apoptotic process; GO:0010720 positive regulation of cell development; GO:0019896 axonal transport of mitochondrion; GO:0032502 developmental process; GO:0007600 sensory perception; GO:0071822 protein complex subunit organization; GO:0060998 regulation of dendritic spine development; GO:0051962 positive regulation of nervous system development; GO:0048522 positive regulation of cellular process; GO:1902582 single-organism intracellular transport; GO:0010639 negative regulation of organelle organization; GO:1902589 single-organism organelle organization; GO:0008088 axo-dendritic transport; GO:0050789 regulation of biological process; GO:0045664 regulation of neuron differentiation; GO:0010638 positive regulation of organelle organization; GO:0007568 aging; GO:0051258 protein polymerization; GO:0070271 protein complex biogenesis; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0072384 organelle transport along microtubule; GO:0016043 cellular component organization; GO:0043069 negative regulation of programmed cell death; GO:0061001 regulation of dendritic spine morphogenesis; GO:0048285 organelle fission; GO:0010770 positive regulation of cell morphogenesis involved in differentiation; GO:0031344 regulation of cell projection organization; GO:0050896 response to stimulus; GO:0099111 microtubule-based transport; GO:0030154 cell differentiation; GO:0048311 mitochondrion distribution; GO:0003373 dynamin family protein polymerization involved in membrane fission; GO:0043066 negative regulation of apoptotic process; GO:0008053 mitochondrial fusion; GO:1902235 regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway; GO:0000002 mitochondrial genome maintenance; GO:0009987 cellular process; GO:0061003 positive regulation of dendritic spine morphogenesis; GO:0045595 regulation of cell differentiation; GO:0043623 cellular protein complex assembly; GO:0034622 cellular macromolecular complex assembly; GO:0003008 system process; GO:0033043 regulation of organelle organization; GO:0044802 single-organism membrane organization; GO:0014042 positive regulation of neuron maturation; GO:0050953 sensory perception of light stimulus; GO:0048585 negative regulation of response to stimulus; GO:0048518 positive regulation of biological process; GO:0000266 mitochondrial fission; GO:0051641 cellular localization; GO:0010822 positive regulation of mitochondrion organization; GO:0043933 macromolecular complex subunit organization; GO:0007018 microtubule-based movement; GO:0050775 positive regulation of dendrite morphogenesis; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:2001242 regulation of intrinsic apoptotic signaling pathway; GO:0022603 regulation of anatomical structure morphogenesis; GO:0050773 regulation of dendrite development; GO:0051128 regulation of cellular component organization; GO:0022604 regulation of cell morphogenesis; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:0050767 regulation of neurogenesis; ","GO:0016020 membrane; GO:0030425 dendrite; GO:0019867 outer membrane; GO:0019898 extrinsic component of membrane; GO:0031090 organelle membrane; GO:0099568 cytoplasmic region; GO:0005737 cytoplasm; GO:0032838 cell projection cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0031970 organelle envelope lumen; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0019866 organelle inner membrane; GO:0043005 neuron projection; GO:0031968 organelle outer membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0097458 neuron part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0098588 bounding membrane of organelle; GO:0044429 mitochondrial part; GO:0031314 extrinsic component of mitochondrial inner membrane; GO:0005741 mitochondrial outer membrane; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0031981 nuclear lumen; GO:0044463 cell projection part; GO:0005829 cytosol; GO:0016021 integral component of membrane; GO:0033267 axon part; GO:0005739 mitochondrion; GO:0030424 axon; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:1904115 axon cytoplasm; GO:0036477 somatodendritic compartment; GO:0005634 nucleus; GO:0005758 mitochondrial intermembrane space; GO:0030061 mitochondrial crista; GO:0031975 envelope; GO:0031312 extrinsic component of organelle membrane; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0008092 cytoskeletal protein binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0008017 microtubule binding; GO:0032550 purine ribonucleoside binding; GO:0003924 GTPase activity; GO:0043169 cation binding; GO:0043168 anion binding; GO:0019001 guanyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0000287 magnesium ion binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0015631 tubulin binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0046872 metal ion binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0032561 guanyl ribonucleotide binding; GO:0036094 small molecule binding; ","K17079",null,null,"IPR030381; IPR001401; IPR027417; ","\"Dynamin-type guanine nucleotide-binding (G) domain; Dynamin, GTPase domain; P-loop containing nucleoside triphosphate hydrolase; \"\r"]
["O60341","Lysine-specific histone demethylase 1A OS=Homo sapiens OX=9606 GN=KDM1A","KDM1A",92.902,6.567,3.6,3,5,3,0.92,1.009,0.979,1.034,0.908,1.154,1.065,0.475,"extracellular\r",{"$cut":{"chars":18862,"head":"GO:0021700 developmental maturation; GO:0010941 regulation of cell death; GO:0048732 gland development; GO:0043009 chordate embryonic development; GO:0016577 histone demethylation; GO:0009891 positive regulation of biosynthetic process; GO:0046683 response to organophosphorus; GO:0032091 negative regulation of protein binding; GO:0044237 cellular metabolic process; GO:1905269 positive regulation of chromatin organization; GO:0008152 metabolic process; GO:1902165 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; GO:0044093 positive regulation of molecular function; GO:0032535 regulation of cellular component size; GO:0009790 embryo development; GO:0051099 positive regulation of binding; GO:0000018 regulation of DNA recombination; GO:0006396 RNA processing; GO:0051716 cellular response to stimulus; GO:0071214 cellular response to abiotic stimulus; GO:0045654 positive regulation of megakaryocyte differentiation; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0002520 immune system development; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0010243 response to organonitrogen compound; GO:0033182 regulation of histone ubiquitination; GO:0051591 response to cAMP; GO:1902532 negative regulation of intracellular signal transduction; GO:0080135 regulation of cellular response to stress; GO:0071480 cellular response to gamma radiation; GO:1902253 regulation of intrinsic apoptotic signaling pathway by p53 class mediator; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:2000179 positive regulation of neural precursor cell proliferation; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0009112 nucleobase metabolic process; GO:0031060 regulation of histone methylation; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0010721 negative regulation of cell development; GO:0016071 mRNA metabolic process; GO:0060548 negative regulation of cell death; GO:0010975 regulation of neuron projection development; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator; GO:0055001 muscle cell development; GO:0044707 single-multicellular organism process; GO:0072091 regulation of stem cell proliferation; GO:0016570 histone modification; GO:1901700 response to oxygen-containing compound; GO:1990138 neuron projection extension; GO:0048519 negative regulation of biological process; GO:1903706 regulation of hemopoiesis; GO:0045892 negative regulation of transcription, DNA-templated; GO:0009653 anatomical structure morphogenesis; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0061061 muscle structure development; GO:1902680 positive regulation of RNA biosynthetic process; GO:1901797 negative regulation of signal transduction by p53 class mediator; GO:0009416 response to light stimulus; GO:0006950 response to stress; GO:0051960 regulation of nervous system development; GO:0060284 regulation of cell development; GO:0008283 cell proliferation; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0006144 purine nucleobase metabolic process; GO:1901576 organic substance biosynthetic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0009890 negative regulation of biosynthetic process; GO:0051569 regulation of histone H3-K4 methylation; GO:2001251 negative regulation of chromosome organization; GO:0031398 positive regulation of protein ubiquitination; GO:0006996 organelle organization; GO:0031325 positive regula"}},"GO:0000784 nuclear chromosome, telomeric region; GO:0000781 chromosome, telomeric region; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044454 nuclear chromosome part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005694 chromosome; GO:0000790 nuclear chromatin; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:1990391 DNA repair complex; GO:0005667 transcription factor complex; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0098687 chromosomal region; GO:0005634 nucleus; GO:0000785 chromatin; GO:0000228 nuclear chromosome; GO:0043234 protein complex; GO:0044428 nuclear part; ","GO:0032453 histone demethylase activity (H3-K4 specific); GO:1901265 nucleoside phosphate binding; GO:0050660 flavin adenine dinucleotide binding; GO:0005102 receptor binding; GO:0042162 telomeric DNA binding; GO:0016787 hydrolase activity; GO:0050681 androgen receptor binding; GO:0005515 protein binding; GO:0003682 chromatin binding; GO:0051427 hormone receptor binding; GO:0003700 transcription factor activity, sequence-specific DNA binding; GO:0000975 regulatory region DNA binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0061752 telomeric repeat-containing RNA binding; GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0001085 RNA polymerase II transcription factor binding; GO:0001071 nucleic acid binding transcription factor activity; GO:0000989 transcription factor activity, transcription factor binding; GO:0035258 steroid hormone receptor binding; GO:0043425 bHLH transcription factor binding; GO:0043168 anion binding; GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; GO:0032454 histone demethylase activity (H3-K9 specific); GO:0003723 RNA binding; GO:0003677 DNA binding; GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific); GO:0043167 ion binding; GO:0000166 nucleotide binding; GO:0003712 transcription cofactor activity; GO:0043565 sequence-specific DNA binding; GO:0048037 cofactor binding; GO:0032451 demethylase activity; GO:0016491 oxidoreductase activity; GO:0004407 histone deacetylase activity; GO:0001067 regulatory region nucleic acid binding; GO:0002039 p53 binding; GO:0033558 protein deacetylase activity; GO:0032452 histone demethylase activity; GO:0044212 transcription regulatory region DNA binding; GO:0003676 nucleic acid binding; GO:0035257 nuclear hormone receptor binding; GO:0019213 deacetylase activity; GO:0003713 transcription coactivator activity; GO:0000988 transcription factor activity, protein binding; GO:0019899 enzyme binding; GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; GO:0008134 transcription factor binding; GO:0043426 MRF binding; GO:0050662 coenzyme binding; GO:0036094 small molecule binding; ","K11450","KDM1A; lysine-specific histone demethylase 1A [EC:1.-.-.-]","hsa04714 Thermogenesis - Homo sapiens (human); ","IPR002937; IPR011991; IPR009057; IPR007526; IPR023753; ","Amine oxidase; Winged helix-turn-helix DNA-binding domain; Homeobox domain-like; SWIRM domain; FAD/NAD(P)-binding domain; \r"]
["O60361","Putative nucleoside diphosphate kinase OS=Homo sapiens OX=9606 GN=NME2P1","NME2P1",15.529,2.4257,66.4,9,20,1,0.985,1.054,0.87,1.029,0.986,1.085,1.066,0.352,"cytoplasm\r","GO:0042278 purine nucleoside metabolic process; GO:0009116 nucleoside metabolic process; GO:0046132 pyrimidine ribonucleoside biosynthetic process; GO:0006165 nucleoside diphosphate phosphorylation; GO:0009147 pyrimidine nucleoside triphosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0046129 purine ribonucleoside biosynthetic process; GO:0009058 biosynthetic process; GO:0009163 nucleoside biosynthetic process; GO:0046939 nucleotide phosphorylation; GO:0046036 CTP metabolic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0046390 ribose phosphate biosynthetic process; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0006213 pyrimidine nucleoside metabolic process; GO:0046134 pyrimidine nucleoside biosynthetic process; GO:1901068 guanosine-containing compound metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:1901070 guanosine-containing compound biosynthetic process; GO:0072527 pyrimidine-containing compound metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0006183 GTP biosynthetic process; GO:0009145 purine nucleoside triphosphate biosynthetic process; GO:0018130 heterocycle biosynthetic process; GO:0009206 purine ribonucleoside triphosphate biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0046051 UTP metabolic process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0046131 pyrimidine ribonucleoside metabolic process; GO:0042451 purine nucleoside biosynthetic process; GO:0090407 organophosphate biosynthetic process; GO:0072522 purine-containing compound biosynthetic process; GO:0044710 single-organism metabolic process; GO:0006228 UTP biosynthetic process; GO:1901657 glycosyl compound metabolic process; GO:0006164 purine nucleotide biosynthetic process; GO:0046039 GTP metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0009201 ribonucleoside triphosphate biosynthetic process; GO:0016310 phosphorylation; GO:0009165 nucleotide biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0009208 pyrimidine ribonucleoside triphosphate metabolic process; GO:0009259 ribonucleotide metabolic process; GO:0009142 nucleoside triphosphate biosynthetic process; GO:0006221 pyrimidine nucleotide biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0072528 pyrimidine-containing compound biosynthetic process; GO:0006241 CTP biosynthetic process; GO:0046483 heterocycle metabolic process; GO:0009220 pyrimidine ribonucleotide biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0009119 ribonucleoside metabolic process; GO:0009132 nucleoside diphosphate metabolic process; GO:0009218 pyrimidine ribonucleotide metabolic process; GO:0044711 single-organism biosynthetic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0009148 pyrimidine nucleoside triphosphate biosynthetic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0042455 ribonucleoside biosynthetic process; GO:1901576 organic substance biosynthetic process; GO:0006163 purine nucleotide metabolic process; GO:0044249 cellular biosynthetic process; GO:0046128 purine ribonucleoside metabolic process; GO:0006220 pyrimidine nucleotide metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0009152 purine ribonucleotide biosynthetic process; GO:0006793 phosphorus metabolic process; GO:1901659 glycosyl compound biosynthetic process; GO:0009260 ribonucleotide biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0009209 pyrimidine ribonucleoside triphosphate biosynthetic process; GO:0009150 purine ribonucleotide metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0004550 nucleoside diphosphate kinase activity; GO:0019205 nucleobase-containing compound kinase activity; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0000166 nucleotide binding; GO:0016776 phosphotransferase activity, phosphate group as acceptor; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016301 kinase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0016740 transferase activity; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; "]
["O60437","Periplakin OS=Homo sapiens OX=9606 GN=PPL","PPL",204.74,323.31,51.6,90,146,90,1.013,1.024,1.006,0.989,1.014,0.98,0.98,0.155,"nucleus\r","GO:0032502 developmental process; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0060429 epithelium development; GO:0043588 skin development; GO:0030216 keratinocyte differentiation; GO:0009888 tissue development; GO:0031424 keratinization; GO:0048731 system development; GO:0070268 cornification; GO:0048869 cellular developmental process; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0032501 multicellular organismal process; GO:0009913 epidermal cell differentiation; GO:0048513 animal organ development; GO:0030154 cell differentiation; GO:0008219 cell death; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0008544 epidermis development; GO:0012501 programmed cell death; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0048856 anatomical structure development; GO:0009987 cellular process; GO:0071840 cellular component organization or biogenesis; GO:0030855 epithelial cell differentiation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0070161 anchoring junction; GO:0044424 intracellular part; GO:0005911 cell-cell junction; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0043228 non-membrane-bounded organelle; GO:0030057 desmosome; GO:0070062 extracellular exosome; GO:0005856 cytoskeleton; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0001533 cornified envelope; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0050839 cell adhesion molecule binding; GO:0005515 protein binding; GO:0005200 structural constituent of cytoskeleton; GO:0005198 structural molecule activity; GO:0005488 binding; GO:0045296 cadherin binding; ","K10386"]
["O60476","Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB OS=Homo sapiens OX=9606 GN=MAN1A2","MAN1A2",73.003,6.8157,2.7,1,1,1,0.922,0.984,0.874,1.087,1.098,1.037,1.159,0.0183,"mitochondria\r","GO:0036508 protein alpha-1,2-demannosylation; GO:0044707 single-multicellular organism process; GO:0043413 macromolecule glycosylation; GO:0030323 respiratory tube development; GO:0006517 protein deglycosylation; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0060541 respiratory system development; GO:1901135 carbohydrate derivative metabolic process; GO:0007275 multicellular organism development; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0070085 glycosylation; GO:0032502 developmental process; GO:0030324 lung development; GO:0035295 tube development; GO:0006486 protein glycosylation; GO:0009101 glycoprotein biosynthetic process; GO:0036507 protein demannosylation; GO:0048731 system development; GO:0044763 single-organism cellular process; GO:0009100 glycoprotein metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0032501 multicellular organismal process; GO:0044249 cellular biosynthetic process; GO:0007585 respiratory gaseous exchange; GO:0048513 animal organ development; GO:0034645 cellular macromolecule biosynthetic process; GO:0044767 single-organism developmental process; GO:0044710 single-organism metabolic process; GO:0006491 N-glycan processing; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:0048856 anatomical structure development; GO:0048286 lung alveolus development; GO:1904381 Golgi apparatus mannose trimming; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0098588 bounding membrane of organelle; GO:0031090 organelle membrane; GO:0031982 vesicle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0000139 Golgi membrane; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0005794 Golgi apparatus; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0015923 mannosidase activity; GO:0015924 mannosyl-oligosaccharide mannosidase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0004559 alpha-mannosidase activity; GO:0043167 ion binding; GO:0016798 hydrolase activity, acting on glycosyl bonds; GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0016787 hydrolase activity; GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; GO:0005509 calcium ion binding; ","K01230","MAN1; mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00510 N-Glycan biosynthesis - Homo sapiens (human); hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); "]
["O60488","Long-chain-fatty-acid--CoA ligase 4 OS=Homo sapiens OX=9606 GN=ACSL4","ACSL4",79.187,52.615,11.1,6,8,5,0.915,0.999,0.969,1.043,1.04,1.019,1.076,0.051,"endoplasmic reticulum\r","GO:0051188 cofactor biosynthetic process; GO:0046486 glycerolipid metabolic process; GO:0022414 reproductive process; GO:0032890 regulation of organic acid transport; GO:0044070 regulation of anion transport; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0035337 fatty-acyl-CoA metabolic process; GO:0051046 regulation of secretion; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0035384 thioester biosynthetic process; GO:0044272 sulfur compound biosynthetic process; GO:0045927 positive regulation of growth; GO:0051234 establishment of localization; GO:0008610 lipid biosynthetic process; GO:0001558 regulation of cell growth; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0015718 monocarboxylic acid transport; GO:0032879 regulation of localization; GO:0006639 acylglycerol metabolic process; GO:0044706 multi-multicellular organism process; GO:0044702 single organism reproductive process; GO:0032306 regulation of prostaglandin secretion; GO:0032787 monocarboxylic acid metabolic process; GO:0009108 coenzyme biosynthetic process; GO:0032891 negative regulation of organic acid transport; GO:0009790 embryo development; GO:0033036 macromolecule localization; GO:0044765 single-organism transport; GO:0006629 lipid metabolic process; GO:0051051 negative regulation of transport; GO:0007399 nervous system development; GO:0006790 sulfur compound metabolic process; GO:0032502 developmental process; GO:0006869 lipid transport; GO:0032369 negative regulation of lipid transport; GO:0034097 response to cytokine; GO:0030307 positive regulation of cell growth; GO:0048699 generation of neurons; GO:0071616 acyl-CoA biosynthetic process; GO:0044281 small molecule metabolic process; GO:0043269 regulation of ion transport; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0006732 coenzyme metabolic process; GO:0035336 long-chain fatty-acyl-CoA metabolic process; GO:0060136 embryonic process involved in female pregnancy; GO:0046942 carboxylic acid transport; GO:0035338 long-chain fatty-acyl-CoA biosynthetic process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0051186 cofactor metabolic process; GO:0032303 regulation of icosanoid secretion; GO:0006810 transport; GO:0051048 negative regulation of secretion; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032304 negative regulation of icosanoid secretion; GO:0030030 cell projection organization; GO:2000192 negative regulation of fatty acid transport; GO:0044710 single-organism metabolic process; GO:0070672 response to interleukin-15; GO:0006082 organic acid metabolic process; GO:0048609 multicellular organismal reproductive process; GO:0048856 anatomical structure development; GO:0043436 oxoacid metabolic process; GO:0050794 regulation of cellular process; GO:0000003 reproduction; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0016358 dendrite development; GO:0046949 fatty-acyl-CoA biosynthetic process; GO:0040008 regulation of growth; GO:0032368 regulation of lipid transport; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0071704 organic substance metabolic process; GO:0007565 female pregnancy; GO:0009991 response to extracellular stimulus; GO:0030154 cell differentiation; GO:0015908 fatty acid transport; GO:1902578 single-organism localization; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0006638 neutral lipid metabolic process; GO:2000191 regulation of fatty acid transport; GO:1903792 negative regulation of anion transport; GO:0043271 negative regulation of ion transport; GO:0044711 single-organism biosynthetic process; GO:0051049 regulation of transport; GO:0048731 system development; GO:0009792 embryo development ending in birth or egg hatching; GO:0035383 thioester metabolic process; GO:0071702 organic substance transport; GO:0010876 lipid localization; GO:0010033 response to organic substance; GO:0006631 fatty acid metabolic process; GO:0031175 neuron projection development; GO:0007584 response to nutrient; GO:0044238 primary metabolic process; GO:0015849 organic acid transport; GO:1901576 organic substance biosynthetic process; GO:0048518 positive regulation of biological process; GO:0006637 acyl-CoA metabolic process; GO:0044249 cellular biosynthetic process; GO:0006820 anion transport; GO:0032504 multicellular organism reproduction; GO:0030182 neuron differentiation; GO:0015711 organic anion transport; GO:0006641 triglyceride metabolic process; GO:0060996 dendritic spine development; GO:0006793 phosphorus metabolic process; GO:0001676 long-chain fatty acid metabolic process; GO:0006811 ion transport; GO:0044767 single-organism developmental process; GO:0044703 multi-organism reproductive process; GO:0019752 carboxylic acid metabolic process; GO:0032307 negative regulation of prostaglandin secretion; GO:0031667 response to nutrient levels; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0019867 outer membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0043025 neuronal cell body; GO:0031224 intrinsic component of membrane; GO:0044438 microbody part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005778 peroxisomal membrane; GO:0005740 mitochondrial envelope; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0042579 microbody; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0031968 organelle outer membrane; GO:0005811 lipid particle; GO:0044233 ER-mitochondrion membrane contact site; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0005789 endoplasmic reticulum membrane; GO:0044232 organelle membrane contact site; GO:0043229 intracellular organelle; GO:0031903 microbody membrane; GO:0044429 mitochondrial part; GO:0044439 peroxisomal part; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005741 mitochondrial outer membrane; GO:0005777 peroxisome; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0036477 somatodendritic compartment; GO:0044432 endoplasmic reticulum part; GO:0031975 envelope; GO:0044297 cell body; GO:0031966 mitochondrial membrane; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0004467 long-chain fatty acid-CoA ligase activity; GO:0047676 arachidonate-CoA ligase activity; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016874 ligase activity; GO:0016877 ligase activity, forming carbon-sulfur bonds; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0015645 fatty acid ligase activity; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0102391 decanoate--CoA ligase activity; GO:0031957 very long-chain fatty acid-CoA ligase activity; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0016878 acid-thiol ligase activity; ","K01897","ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]","hsa00061 Fatty acid biosynthesis - Homo sapiens (human); hsa04920 Adipocytokine signaling pathway - Homo sapiens (human); hsa03320 PPAR signaling pathway - Homo sapiens (human); hsa00071 Fatty acid degradation - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa01212 Fatty acid metabolism - Homo sapiens (human); hsa04216 Ferroptosis - Homo sapiens (human); hsa04146 Peroxisome - Homo sapiens (human); ","IPR000873; ","AMP-dependent synthetase/ligase; \r"]
["O60493","Sorting nexin-3 OS=Homo sapiens OX=9606 GN=SNX3","SNX3",18.762,36.254,39.5,8,15,7,1.047,1.023,0.953,0.988,1.003,1.008,0.992,0.815,"cytoplasm\r","GO:0044700 single organism signaling; GO:0060627 regulation of vesicle-mediated transport; GO:0007166 cell surface receptor signaling pathway; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0009607 response to biotic stimulus; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0032387 negative regulation of intracellular transport; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0016055 Wnt signaling pathway; GO:0008104 protein localization; GO:0007399 nervous system development; GO:0051051 negative regulation of transport; GO:0051716 cellular response to stimulus; GO:0046597 negative regulation of viral entry into host cell; GO:0080090 regulation of primary metabolic process; GO:0031346 positive regulation of cell projection organization; GO:0048699 generation of neurons; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0007267 cell-cell signaling; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0051223 regulation of protein transport; GO:0006464 cellular protein modification process; GO:2000642 negative regulation of early endosome to late endosome transport; GO:0051094 positive regulation of developmental process; GO:0010975 regulation of neuron projection development; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0044267 cellular protein metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0051239 regulation of multicellular organismal process; GO:0045597 positive regulation of cell differentiation; GO:0060341 regulation of cellular localization; GO:1903901 negative regulation of viral life cycle; GO:0045806 negative regulation of endocytosis; GO:0070676 intralumenal vesicle formation; GO:2000641 regulation of early endosome to late endosome transport; GO:0007275 multicellular organism development; GO:0032880 regulation of protein localization; GO:0042176 regulation of protein catabolic process; GO:0009966 regulation of signal transduction; GO:0009617 response to bacterium; GO:0030100 regulation of endocytosis; GO:0051224 negative regulation of protein transport; GO:0048731 system development; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0043900 regulation of multi-organism process; GO:0016192 vesicle-mediated transport; GO:0022615 protein to membrane docking; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0045184 establishment of protein localization; GO:0030111 regulation of Wnt signaling pathway; GO:0010976 positive regulation of neuron projection development; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0006900 membrane budding; GO:0050769 positive regulation of neurogenesis; GO:0043412 macromolecule modification; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0070646 protein modification by small protein removal; GO:0010256 endomembrane system organization; GO:0045666 positive regulation of neuron differentiation; GO:0023051 regulation of signaling; GO:0051129 negative regulation of cellular component organization; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0046596 regulation of viral entry into host cell; GO:0033036 macromolecule localization; GO:0010720 positive regulation of cell development; GO:0050764 regulation of phagocytosis; GO:0048525 negative regulation of viral process; GO:0032502 developmental process; GO:1903649 regulation of cytoplasmic transport; GO:0051962 positive regulation of nervous system development; GO:0048522 positive regulation of cellular process; GO:0032386 regulation of intracellular transport; GO:0070647 protein modification by small protein conjugation or removal; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0198738 cell-cell signaling by wnt; GO:0050789 regulation of biological process; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0045664 regulation of neuron differentiation; GO:0019222 regulation of metabolic process; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0016043 cellular component organization; GO:0042177 negative regulation of protein catabolic process; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0060255 regulation of macromolecule metabolic process; GO:0010324 membrane invagination; GO:0031344 regulation of cell projection organization; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0016579 protein deubiquitination; GO:0050765 negative regulation of phagocytosis; GO:0051707 response to other organism; GO:0022406 membrane docking; GO:0070201 regulation of establishment of protein localization; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0006508 proteolysis; GO:0009895 negative regulation of catabolic process; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0051049 regulation of transport; GO:0050792 regulation of viral process; GO:0016050 vesicle organization; GO:0048518 positive regulation of biological process; GO:1903650 negative regulation of cytoplasmic transport; GO:0043901 negative regulation of multi-organism process; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0051248 negative regulation of protein metabolic process; GO:1904950 negative regulation of establishment of protein localization; GO:0051128 regulation of cellular component organization; GO:1903900 regulation of viral life cycle; GO:0007032 endosome organization; GO:0050767 regulation of neurogenesis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0019898 extrinsic component of membrane; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0070062 extracellular exosome; GO:0030136 clathrin-coated vesicle; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0031901 early endosome membrane; GO:0030139 endocytic vesicle; GO:0043227 membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0010008 endosome membrane; GO:0098588 bounding membrane of organelle; GO:0032009 early phagosome; GO:0044446 intracellular organelle part; GO:0045335 phagocytic vesicle; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0030135 coated vesicle; GO:0043226 organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901981 phosphatidylinositol phosphate binding; GO:0019903 protein phosphatase binding; GO:0043167 ion binding; GO:0080025 phosphatidylinositol-3,5-bisphosphate binding; GO:0005515 protein binding; GO:1902936 phosphatidylinositol bisphosphate binding; GO:0032266 phosphatidylinositol-3-phosphate binding; GO:0005488 binding; GO:0010314 phosphatidylinositol-5-phosphate binding; GO:0035091 phosphatidylinositol binding; GO:0005543 phospholipid binding; GO:0008289 lipid binding; GO:0043168 anion binding; GO:0019902 phosphatase binding; GO:0070273 phosphatidylinositol-4-phosphate binding; GO:0019899 enzyme binding; ","K17918","SNX3_12; sorting nexin-3/12","hsa04144 Endocytosis - Homo sapiens (human); ","IPR001683; ","Phox homologous domain; \r"]
["O60496","Docking protein 2 OS=Homo sapiens OX=9606 GN=DOK2","DOK2",45.378,4.8052,2.7,1,1,1,0.936,0.934,0.967,1.07,1.077,1.018,1.116,0.00656,"nucleus\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0016477 cell migration; GO:0051674 localization of cell; GO:0007166 cell surface receptor signaling pathway; GO:0048869 cellular developmental process; GO:0048666 neuron development; GO:0032989 cellular component morphogenesis; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0007411 axon guidance; GO:0048468 cell development; GO:0000904 cell morphogenesis involved in differentiation; GO:0009605 response to external stimulus; GO:0009653 anatomical structure morphogenesis; GO:0030154 cell differentiation; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0032990 cell part morphogenesis; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0007409 axonogenesis; GO:0048858 cell projection morphogenesis; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0035556 intracellular signal transduction; GO:0048699 generation of neurons; GO:0048731 system development; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0048812 neuron projection morphogenesis; GO:0002376 immune system process; GO:0048870 cell motility; GO:0007264 small GTPase mediated signal transduction; GO:0031175 neuron projection development; GO:0023052 signaling; GO:0006935 chemotaxis; GO:0032501 multicellular organismal process; GO:0000902 cell morphogenesis; GO:0030182 neuron differentiation; GO:0061564 axon development; GO:0042221 response to chemical; GO:0050900 leukocyte migration; GO:0050789 regulation of biological process; GO:0097485 neuron projection guidance; GO:0030030 cell projection organization; GO:0044767 single-organism developmental process; GO:0006928 movement of cell or subcellular component; GO:0042330 taxis; GO:0040011 locomotion; GO:0051179 localization; GO:0048856 anatomical structure development; GO:0007265 Ras protein signal transduction; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:0030674 protein binding, bridging; GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity; GO:1990782 protein tyrosine kinase binding; GO:0005102 receptor binding; GO:0044877 macromolecular complex binding; GO:0019901 protein kinase binding; GO:0005515 protein binding; GO:0019900 kinase binding; GO:0004871 signal transducer activity; GO:0005158 insulin receptor binding; GO:0005057 signal transducer activity, downstream of receptor; GO:0035591 signaling adaptor activity; GO:0030971 receptor tyrosine kinase binding; GO:0005488 binding; GO:0060090 binding, bridging; GO:0019899 enzyme binding; GO:0032403 protein complex binding; ","K20234",null,null,"IPR011993; IPR002404; IPR001849; ","PH domain-like; IRS-type PTB domain; Pleckstrin homology domain; \r"]
["O60502","Protein O-GlcNAcase OS=Homo sapiens OX=9606 GN=MGEA5","MGEA5",102.91,15.105,6.3,5,6,5,0.904,0.963,1.054,1.104,0.881,1.099,1.056,0.589,"cytoplasm\r","GO:0043413 macromolecule glycosylation; GO:1901071 glucosamine-containing compound metabolic process; GO:0006517 protein deglycosylation; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:1901135 carbohydrate derivative metabolic process; GO:0044248 cellular catabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0070085 glycosylation; GO:0006486 protein glycosylation; GO:0044265 cellular macromolecule catabolic process; GO:0009101 glycoprotein biosynthetic process; GO:0006516 glycoprotein catabolic process; GO:0044763 single-organism cellular process; GO:1901136 carbohydrate derivative catabolic process; GO:0009100 glycoprotein metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:1901575 organic substance catabolic process; GO:0006044 N-acetylglucosamine metabolic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044710 single-organism metabolic process; GO:0030163 protein catabolic process; GO:0009057 macromolecule catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006040 amino sugar metabolic process; GO:0006464 cellular protein modification process; GO:0006493 protein O-linked glycosylation; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:0009056 catabolic process; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:0003824 catalytic activity; GO:0004415 hyalurononglucosaminidase activity; GO:0016798 hydrolase activity, acting on glycosyl bonds; GO:0004563 beta-N-acetylhexosaminidase activity; GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds; GO:0016231 beta-N-acetylglucosaminidase activity; GO:0016787 hydrolase activity; GO:0015929 hexosaminidase activity; ","K15719","NCOAT; protein O-GlcNAcase / histone acetyltransferase [EC:3.2.1.169 2.3.1.48]","hsa04931 Insulin resistance - Homo sapiens (human); ","IPR017853; IPR016181; ","Glycoside hydrolase superfamily; Acyl-CoA N-acyltransferase; \r"]
["O60504","Vinexin OS=Homo sapiens OX=9606 GN=SORBS3","SORBS3",75.34,24.955,14,7,9,7,1.101,1.211,0.994,0.909,0.918,0.877,0.818,0.028,"nucleus\r","GO:0003012 muscle system process; GO:0032270 positive regulation of cellular protein metabolic process; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0051253 negative regulation of RNA metabolic process; GO:0051130 positive regulation of cellular component organization; GO:0022610 biological adhesion; GO:2001141 regulation of RNA biosynthetic process; GO:0030036 actin cytoskeleton organization; GO:0010646 regulation of cell communication; GO:0009893 positive regulation of metabolic process; GO:0007155 cell adhesion; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0051493 regulation of cytoskeleton organization; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0042325 regulation of phosphorylation; GO:0010468 regulation of gene expression; GO:0051174 regulation of phosphorus metabolic process; GO:0045937 positive regulation of phosphate metabolic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0000122 negative regulation of transcription from RNA polymerase II promoter; GO:0048522 positive regulation of cellular process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0010605 negative regulation of macromolecule metabolic process; GO:1902589 single-organism organelle organization; GO:1903506 regulation of nucleic acid-templated transcription; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0010638 positive regulation of organelle organization; GO:0048583 regulation of response to stimulus; GO:1902679 negative regulation of RNA biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:1902905 positive regulation of supramolecular fiber organization; GO:0019220 regulation of phosphate metabolic process; GO:0032233 positive regulation of actin filament bundle assembly; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0097435 supramolecular fiber organization; GO:1902903 regulation of supramolecular fiber organization; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0032956 regulation of actin cytoskeleton organization; GO:0060255 regulation of macromolecule metabolic process; GO:0031399 regulation of protein modification process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0007015 actin filament organization; GO:0044087 regulation of cellular component biogenesis; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0045892 negative regulation of transcription, DNA-templated; GO:0006936 muscle contraction; GO:0043408 regulation of MAPK cascade; GO:0023056 positive regulation of signaling; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0010647 positive regulation of cell communication; GO:0007010 cytoskeleton organization; GO:0009966 regulation of signal transduction; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0009987 cellular process; GO:1902531 regulation of intracellular signal transduction; GO:0006355 regulation of transcription, DNA-templated; GO:0003008 system process; GO:0051495 positive regulation of cytoskeleton organization; GO:0010629 negative regulation of gene expression; GO:0032231 regulation of actin filament bundle assembly; GO:0001932 regulation of protein phosphorylation; GO:0031401 positive regulation of protein modification process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0033043 regulation of organelle organization; GO:0032970 regulation of actin filament-based process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0001934 positive regulation of protein phosphorylation; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0009892 negative regulation of metabolic process; GO:0051492 regulation of stress fiber assembly; GO:0009890 negative regulation of biosynthetic process; GO:0051247 positive regulation of protein metabolic process; GO:0031589 cell-substrate adhesion; GO:0051246 regulation of protein metabolic process; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0030029 actin filament-based process; GO:0051496 positive regulation of stress fiber assembly; GO:0009967 positive regulation of signal transduction; GO:0051128 regulation of cellular component organization; GO:0031327 negative regulation of cellular biosynthetic process; GO:0043410 positive regulation of MAPK cascade; GO:0048584 positive regulation of response to stimulus; GO:0044089 positive regulation of cellular component biogenesis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0070161 anchoring junction; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0005856 cytoskeleton; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0044444 cytoplasmic part; ","GO:0008092 cytoskeletal protein binding; GO:0005200 structural constituent of cytoskeleton; GO:0017166 vinculin binding; GO:0005488 binding; GO:0005515 protein binding; GO:0005198 structural molecule activity; GO:0008134 transcription factor binding; ",{"$nulls":3},"IPR001452; IPR003127; ","SH3 domain; SoHo domain; \r"]
["O60506","Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP","SYNCRIP",69.602,208.84,34.2,21,41,15,0.911,0.92,0.899,1.126,1.122,1.063,1.213,0.000622,"nucleus\r","GO:0001649 osteoblast differentiation; GO:0065008 regulation of biological quality; GO:0043489 RNA stabilization; GO:0010608 posttranscriptional regulation of gene expression; GO:0048869 cellular developmental process; GO:0071346 cellular response to interferon-gamma; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0071345 cellular response to cytokine stimulus; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0070887 cellular response to chemical stimulus; GO:0006396 RNA processing; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0051716 cellular response to stimulus; GO:0031326 regulation of cellular biosynthetic process; GO:0034097 response to cytokine; GO:0080090 regulation of primary metabolic process; GO:0001503 ossification; GO:0044763 single-organism cellular process; GO:0034249 negative regulation of cellular amide metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0042221 response to chemical; GO:0090304 nucleic acid metabolic process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0006952 defense response; GO:0016071 mRNA metabolic process; GO:0048255 mRNA stabilization; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0017148 negative regulation of translation; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0045087 innate immune response; GO:0043487 regulation of RNA stability; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0030154 cell differentiation; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0016032 viral process; GO:0009889 regulation of biosynthetic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0070934 CRD-mediated mRNA stabilization; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0006950 response to stress; GO:0010629 negative regulation of gene expression; GO:0006807 nitrogen compound metabolic process; GO:0002376 immune system process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0010033 response to organic substance; GO:0034341 response to interferon-gamma; GO:0044238 primary metabolic process; GO:0043488 regulation of mRNA stability; GO:0009892 negative regulation of metabolic process; GO:0034248 regulation of cellular amide metabolic process; GO:0009890 negative regulation of biosynthetic process; GO:0006417 regulation of translation; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0051248 negative regulation of protein metabolic process; GO:0010467 gene expression; GO:0031327 negative regulation of cellular biosynthetic process; GO:0006955 immune response; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0097452 GAIT complex; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0070937 CRD-mediated mRNA stability complex; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0071204 histone pre-mRNA 3'end processing complex; GO:0031981 nuclear lumen; GO:0005681 spliceosomal complex; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0071013 catalytic step 2 spliceosome; GO:1990904 ribonucleoprotein complex; GO:0043234 protein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0008143 poly(A) binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:1901265 nucleoside phosphate binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0070717 poly-purine tract binding; GO:0036094 small molecule binding; GO:0003727 single-stranded RNA binding; ","K13160",null,null,"IPR000504; IPR012677; ","RNA recognition motif domain; Nucleotide-binding alpha-beta plait domain; \r"]
["O60508","Pre-mRNA-processing factor 17 OS=Homo sapiens OX=9606 GN=CDC40","CDC40",65.521,2.8313,3.1,2,2,2,0.804,0.817,0.846,1.102,1.205,1.208,1.425,0.000465,"nucleus\r","GO:0050658 RNA transport; GO:0097659 nucleic acid-templated transcription; GO:0009058 biosynthetic process; GO:0051168 nuclear export; GO:0051169 nuclear transport; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006353 DNA-templated transcription, termination; GO:0071427 mRNA-containing ribonucleoprotein complex export from nucleus; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0050657 nucleic acid transport; GO:0015931 nucleobase-containing compound transport; GO:0043170 macromolecule metabolic process; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0006396 RNA processing; GO:0018130 heterocycle biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0006611 protein export from nucleus; GO:0071166 ribonucleoprotein complex localization; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:0006810 transport; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0044260 cellular macromolecule metabolic process; GO:0006913 nucleocytoplasmic transport; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0031123 RNA 3'-end processing; GO:0046907 intracellular transport; GO:0006725 cellular aromatic compound metabolic process; GO:0031124 mRNA 3'-end processing; GO:0051028 mRNA transport; GO:0051236 establishment of RNA localization; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0006886 intracellular protein transport; GO:0034641 cellular nitrogen compound metabolic process; GO:0034613 cellular protein localization; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0008380 RNA splicing; GO:0006406 mRNA export from nucleus; GO:0006369 termination of RNA polymerase II transcription; GO:0006403 RNA localization; GO:0006405 RNA export from nucleus; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0071426 ribonucleoprotein complex export from nucleus; GO:0006366 transcription from RNA polymerase II promoter; GO:0010467 gene expression; GO:0051179 localization; GO:0071705 nitrogen compound transport; ","GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005681 spliceosomal complex; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0071013 catalytic step 2 spliceosome; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005515 protein binding; GO:0005488 binding; GO:0003676 nucleic acid binding; ","K12816","CDC40; pre-mRNA-processing factor 17","hsa03040 Spliceosome - Homo sapiens (human); ","IPR017986; IPR015943; ","WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain; \r"]
["O60547","GDP-mannose 4,6 dehydratase OS=Homo sapiens OX=9606 GN=GMDS","GMDS",41.949,10.288,11.3,4,4,4,1.059,1.181,1.18,0.947,0.83,0.832,0.763,0.00872,"mitochondria\r","GO:0009226 nucleotide-sugar biosynthetic process; GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0006725 cellular aromatic compound metabolic process; GO:0007166 cell surface receptor signaling pathway; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0007154 cell communication; GO:0046483 heterocycle metabolic process; GO:0019673 GDP-mannose metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0007219 Notch signaling pathway; GO:0009987 cellular process; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0046368 GDP-L-fucose metabolic process; GO:0044238 primary metabolic process; GO:0023052 signaling; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0050789 regulation of biological process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0042350 GDP-L-fucose biosynthetic process; GO:0009225 nucleotide-sugar metabolic process; GO:0042351 'de novo' GDP-L-fucose biosynthetic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0065007 biological regulation; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0043167 ion binding; GO:0016829 lyase activity; GO:0016836 hydro-lyase activity; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0048037 cofactor binding; GO:0016835 carbon-oxygen lyase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0050661 NADP binding; GO:0043168 anion binding; GO:0008446 GDP-mannose 4,6-dehydratase activity; GO:0070401 NADP+ binding; GO:0050662 coenzyme binding; GO:0036094 small molecule binding; ","K01711","gmd; GDPmannose 4,6-dehydratase [EC:4.2.1.47]","hsa00051 Fructose and mannose metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00520 Amino sugar and nucleotide sugar metabolism - Homo sapiens (human); ","IPR016040; ","NAD(P)-binding domain; \r"]
["O60565","Gremlin-1 OS=Homo sapiens OX=9606 GN=GREM1","GREM1",20.697,4.1386,14.1,2,2,2,1.101,1.103,1.01,0.985,0.879,0.945,0.874,0.0378,"extracellular\r",{"$cut":{"chars":22442,"head":"GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0090130 tissue migration; GO:0061333 renal tubule morphogenesis; GO:0030199 collagen fibril organization; GO:0035148 tube formation; GO:0009891 positive regulation of biosynthetic process; GO:0045445 myoblast differentiation; GO:0010469 regulation of receptor activity; GO:0048754 branching morphogenesis of an epithelial tube; GO:0001558 regulation of cell growth; GO:0009953 dorsal/ventral pattern formation; GO:0001525 angiogenesis; GO:0070664 negative regulation of leukocyte proliferation; GO:0065003 macromolecular complex assembly; GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling; GO:0044093 positive regulation of molecular function; GO:1904018 positive regulation of vasculature development; GO:0009790 embryo development; GO:0048598 embryonic morphogenesis; GO:0051147 regulation of muscle cell differentiation; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:1900155 negative regulation of bone trabecula formation; GO:0055025 positive regulation of cardiac muscle tissue development; GO:0048259 regulation of receptor-mediated endocytosis; GO:0051054 positive regulation of DNA metabolic process; GO:0080090 regulation of primary metabolic process; GO:0001763 morphogenesis of a branching structure; GO:0035239 tube morphogenesis; GO:0044763 single-organism cellular process; GO:0060828 regulation of canonical Wnt signaling pathway; GO:0090287 regulation of cellular response to growth factor stimulus; GO:0048870 cell motility; GO:0001656 metanephros development; GO:0051092 positive regulation of NF-kappaB transcription factor activity; GO:0007267 cell-cell signaling; GO:0048583 regulation of response to stimulus; GO:0033689 negative regulation of osteoblast proliferation; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0048263 determination of dorsal identity; GO:0051149 positive regulation of muscle cell differentiation; GO:0051223 regulation of protein transport; GO:0060231 mesenchymal to epithelial transition; GO:0072172 mesonephric tubule formation; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0071675 regulation of mononuclear cell migration; GO:1901863 positive regulation of muscle tissue development; GO:0060548 negative regulation of cell death; GO:0042307 positive regulation of protein import into nucleus; GO:0030855 epithelial cell differentiation; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0072359 circulatory system development; GO:0002009 morphogenesis of an epithelium; GO:0044707 single-multicellular organism process; GO:0003257 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation; GO:0007389 pattern specification process; GO:0048519 negative regulation of biological process; GO:0042990 regulation of transcription factor import into nucleus; GO:0060688 regulation of morphogenesis of a branching structure; GO:0045892 negative regulation of transcription, DNA-templated; GO:0009653 anatomical structure morphogenesis; GO:0023057 negative regulation of signaling; GO:0061098 positive regulation of protein tyrosine kinase activity; GO:0010648 negative regulation of cell communication; GO:2000145 regulation of cell motility; GO:0009889 regulation of biosynthetic process; GO:0043062 extracellular structure organization; GO:0061061 muscle structure development; GO:1902680 positive regulation of RNA biosynthetic process; GO:0061037 negative regulation of cartilage development; GO:0016331 morphogenesis of embryonic epithelium; GO:0072283 metanephric renal vesicle morphogenesis; GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation; GO:0048646 anatomical structure formation involved in morphogenesis; GO:1900086 positive regulation of peptidyl-tyrosine autophosphorylation; GO:0001822 kidney development; GO:0060562 epithelial tube morphogenesis; GO:0030502 negative regulation of bone mi"}},"GO:0009986 cell surface; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005623 cell; GO:0044464 cell part; GO:0005576 extracellular region; ","GO:0030546 receptor activator activity; GO:0030297 transmembrane receptor protein tyrosine kinase activator activity; GO:0048018 receptor agonist activity; GO:0030295 protein kinase activator activity; GO:0005102 receptor binding; GO:0005126 cytokine receptor binding; GO:0016015 morphogen activity; GO:0030296 protein tyrosine kinase activator activity; GO:0070851 growth factor receptor binding; GO:0005172 vascular endothelial growth factor receptor binding; GO:0005515 protein binding; GO:0019207 kinase regulator activity; GO:0019887 protein kinase regulator activity; GO:0098772 molecular function regulator; GO:0004871 signal transducer activity; GO:0019955 cytokine binding; GO:0019209 kinase activator activity; GO:0005125 cytokine activity; GO:0030545 receptor regulator activity; GO:0030234 enzyme regulator activity; GO:0043184 vascular endothelial growth factor receptor 2 binding; GO:0005488 binding; GO:0036122 BMP binding; GO:0008047 enzyme activator activity; ",{"$nulls":3},"IPR004133; IPR006207; ","\"DAN; Cystine knot, C-terminal; \"\r"]
["O60568","Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 OS=Homo sapiens OX=9606 GN=PLOD3","PLOD3",84.784,9.6923,6.9,5,6,5,1.019,1.111,1.136,0.86,0.959,0.932,0.842,0.021,"extracellular\r","GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0030199 collagen fibril organization; GO:0043009 chordate embryonic development; GO:0030323 respiratory tube development; GO:0048869 cellular developmental process; GO:0032989 cellular component morphogenesis; GO:0044699 single-organism process; GO:0045446 endothelial cell differentiation; GO:0097746 regulation of blood vessel diameter; GO:0071711 basement membrane organization; GO:0048729 tissue morphogenesis; GO:0008152 metabolic process; GO:0022607 cellular component assembly; GO:0009719 response to endogenous stimulus; GO:0008544 epidermis development; GO:0030198 extracellular matrix organization; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0009790 embryo development; GO:0070887 cellular response to chemical stimulus; GO:0007399 nervous system development; GO:0030324 lung development; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0035295 tube development; GO:0060429 epithelium development; GO:0002064 epithelial cell development; GO:0009888 tissue development; GO:0071822 protein complex subunit organization; GO:0055114 oxidation-reduction process; GO:0070831 basement membrane assembly; GO:0044763 single-organism cellular process; GO:0032501 multicellular organismal process; GO:0035296 regulation of tube diameter; GO:0000902 cell morphogenesis; GO:0048513 animal organ development; GO:0042221 response to chemical; GO:0001701 in utero embryonic development; GO:0032870 cellular response to hormone stimulus; GO:0044710 single-organism metabolic process; GO:0009887 animal organ morphogenesis; GO:0003013 circulatory system process; GO:0048856 anatomical structure development; GO:0097435 supramolecular fiber organization; GO:0030855 epithelial cell differentiation; GO:0044707 single-multicellular organism process; GO:0060425 lung morphogenesis; GO:0016043 cellular component organization; GO:0002009 morphogenesis of an epithelium; GO:0050880 regulation of blood vessel size; GO:0071310 cellular response to organic substance; GO:0048730 epidermis morphogenesis; GO:0003018 vascular process in circulatory system; GO:0050896 response to stimulus; GO:0021915 neural tube development; GO:0048468 cell development; GO:0000904 cell morphogenesis involved in differentiation; GO:0009653 anatomical structure morphogenesis; GO:0030154 cell differentiation; GO:0060541 respiratory system development; GO:0043062 extracellular structure organization; GO:0008015 blood circulation; GO:0007275 multicellular organism development; GO:0035150 regulation of tube size; GO:0009987 cellular process; GO:0003008 system process; GO:0097755 positive regulation of blood vessel diameter; GO:0048731 system development; GO:0009792 embryo development ending in birth or egg hatching; GO:0010033 response to organic substance; GO:0085029 extracellular matrix assembly; GO:0003158 endothelium development; GO:0043933 macromolecular complex subunit organization; GO:0042311 vasodilation; GO:0001886 endothelial cell morphogenesis; GO:0003382 epithelial cell morphogenesis; GO:0071495 cellular response to endogenous stimulus; GO:0001885 endothelial cell development; GO:0044767 single-organism developmental process; GO:0090066 regulation of anatomical structure size; GO:0051179 localization; GO:0009725 response to hormone; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0030867 rough endoplasmic reticulum membrane; GO:0098588 bounding membrane of organelle; GO:0031090 organelle membrane; GO:0005791 rough endoplasmic reticulum; GO:0031982 vesicle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044432 endoplasmic reticulum part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; ","GO:0019842 vitamin binding; GO:0005506 iron ion binding; GO:0016758 transferase activity, transferring hexosyl groups; GO:0070815 peptidyl-lysine 5-dioxygenase activity; GO:0008378 galactosyltransferase activity; GO:0031418 L-ascorbic acid binding; GO:0043167 ion binding; GO:0043177 organic acid binding; GO:0046527 glucosyltransferase activity; GO:0008194 UDP-glycosyltransferase activity; GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; GO:0005515 protein binding; GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; GO:0048029 monosaccharide binding; GO:0050211 procollagen galactosyltransferase activity; GO:0016491 oxidoreductase activity; GO:0035250 UDP-galactosyltransferase activity; GO:0031406 carboxylic acid binding; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0008475 procollagen-lysine 5-dioxygenase activity; GO:0051213 dioxygenase activity; GO:0005488 binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0030246 carbohydrate binding; GO:0016757 transferase activity, transferring glycosyl groups; GO:0043168 anion binding; GO:0033823 procollagen glucosyltransferase activity; GO:0016740 transferase activity; GO:0036094 small molecule binding; ","K13646","PLOD3; lysyl hydroxylase/galactosyltransferase/glucosyltransferase [EC:1.14.11.4 2.4.1.50 2.4.1.66]","hsa00514 Other types of O-glycan biosynthesis - Homo sapiens (human); hsa00310 Lysine degradation - Homo sapiens (human); ","IPR006620; IPR005123; IPR029044; ","\"Prolyl 4-hydroxylase, alpha subunit; Oxoglutarate/iron-dependent dioxygenase; Nucleotide-diphospho-sugar transferases; \"\r"]
["O60609","GDNF family receptor alpha-3 OS=Homo sapiens OX=9606 GN=GFRA3","GFRA3",44.51,4.6791,3.2,1,1,1,1.191,1.291,1.024,0.879,0.867,0.787,0.722,0.0135,"extracellular\r","GO:0044700 single organism signaling; GO:0051674 localization of cell; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0032989 cellular component morphogenesis; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0048483 autonomic nervous system development; GO:0007154 cell communication; GO:0032990 cell part morphogenesis; GO:0044093 positive regulation of molecular function; GO:0048858 cell projection morphogenesis; GO:0001764 neuron migration; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0007422 peripheral nervous system development; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0048485 sympathetic nervous system development; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0048812 neuron projection morphogenesis; GO:0048870 cell motility; GO:0023052 signaling; GO:0006935 chemotaxis; GO:0032501 multicellular organismal process; GO:0000902 cell morphogenesis; GO:0000165 MAPK cascade; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0051336 regulation of hydrolase activity; GO:0030030 cell projection organization; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0044260 cellular macromolecule metabolic process; GO:0065009 regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0006464 cellular protein modification process; GO:0042330 taxis; GO:0040011 locomotion; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0050794 regulation of cellular process; GO:0016477 cell migration; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0016310 phosphorylation; GO:0044267 cellular protein metabolic process; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0007411 axon guidance; GO:0071704 organic substance metabolic process; GO:0000904 cell morphogenesis involved in differentiation; GO:0009653 anatomical structure morphogenesis; GO:0030154 cell differentiation; GO:0006468 protein phosphorylation; GO:0051345 positive regulation of hydrolase activity; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0007409 axonogenesis; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0023014 signal transduction by protein phosphorylation; GO:0043547 positive regulation of GTPase activity; GO:0035556 intracellular signal transduction; GO:0048731 system development; GO:0031175 neuron projection development; GO:0044238 primary metabolic process; GO:0043085 positive regulation of catalytic activity; GO:0030182 neuron differentiation; GO:0061564 axon development; GO:0006793 phosphorus metabolic process; GO:0097485 neuron projection guidance; GO:0044767 single-organism developmental process; GO:0006928 movement of cell or subcellular component; GO:0051179 localization; GO:0043412 macromolecule modification; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0009897 external side of plasma membrane; GO:0019898 extrinsic component of membrane; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031225 anchored component of membrane; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005886 plasma membrane; GO:0044459 plasma membrane part; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0009986 cell surface; GO:0044444 cytoplasmic part; GO:0098552 side of membrane; ","GO:0038023 signaling receptor activity; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0005085 guanyl-nucleotide exchange factor activity; GO:0008046 axon guidance receptor activity; GO:0005102 receptor binding; GO:0005488 binding; GO:0005088 Ras guanyl-nucleotide exchange factor activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0004888 transmembrane signaling receptor activity; GO:0004871 signal transducer activity; GO:0099600 transmembrane receptor activity; ",{"$nulls":3},"IPR016017; ","GDNF/GAS1; \r"]
["O60610","Protein diaphanous homolog 1 OS=Homo sapiens OX=9606 GN=DIAPH1","DIAPH1",141.35,75.408,14.5,16,19,16,0.854,0.878,0.893,1.112,1.021,1.123,1.24,0.00286,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0030335 positive regulation of cell migration; GO:0045321 leukocyte activation; GO:0040017 positive regulation of locomotion; GO:0044699 single-organism process; GO:0050877 neurological system process; GO:0030041 actin filament polymerization; GO:0051234 establishment of localization; GO:0030036 actin cytoskeleton organization; GO:0022607 cellular component assembly; GO:0008360 regulation of cell shape; GO:0065003 macromolecular complex assembly; GO:0032879 regulation of localization; GO:0009719 response to endogenous stimulus; GO:0033365 protein localization to organelle; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0070887 cellular response to chemical stimulus; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0007600 sensory perception; GO:0002443 leukocyte mediated immunity; GO:0071822 protein complex subunit organization; GO:0051279 regulation of release of sequestered calcium ion into cytosol; GO:0060359 response to ammonium ion; GO:0002446 neutrophil mediated immunity; GO:0043269 regulation of ion transport; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0008154 actin polymerization or depolymerization; GO:0051272 positive regulation of cellular component movement; GO:0071242 cellular response to ammonium ion; GO:0032501 multicellular organismal process; GO:0002444 myeloid leukocyte mediated immunity; GO:0034776 response to histamine; GO:0032886 regulation of microtubule-based process; GO:0071417 cellular response to organonitrogen compound; GO:0006810 transport; GO:0034762 regulation of transmembrane transport; GO:1902589 single-organism organelle organization; GO:0010243 response to organonitrogen compound; GO:0044380 protein localization to cytoskeleton; GO:0072698 protein localization to microtubule cytoskeleton; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:1901699 cellular response to nitrogen compound; GO:0032940 secretion by cell; GO:1901698 response to nitrogen compound; GO:0051258 protein polymerization; GO:0043299 leukocyte degranulation; GO:0070271 protein complex biogenesis; GO:0097435 supramolecular fiber organization; GO:0050954 sensory perception of mechanical stimulus; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0002283 neutrophil activation involved in immune response; GO:2000021 regulation of ion homeostasis; GO:0002252 immune effector process; GO:0071310 cellular response to organic substance; GO:0007015 actin filament organization; GO:2000147 positive regulation of cell motility; GO:0032844 regulation of homeostatic process; GO:0050896 response to stimulus; GO:0060341 regulation of cellular localization; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:2000145 regulation of cell motility; GO:1903169 regulation of calcium ion transmembrane transport; GO:0010959 regulation of metal ion transport; GO:0036230 granulocyte activation; GO:0034613 cellular protein localization; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:1904062 regulation of cation transmembrane transport; GO:0043623 cellular protein complex assembly; GO:0034622 cellular macromolecular complex assembly; GO:0003008 system process; GO:0051282 regulation of sequestering of calcium ion; GO:0051270 regulation of cellular component movement; GO:0051049 regulation of transport; GO:0016192 vesicle-mediated transport; GO:0090279 regulation of calcium ion import; GO:0051924 regulation of calcium ion transport; GO:0071407 cellular response to organic cyclic compound; GO:0002376 immune system process; GO:0030334 regulation of cell migration; GO:0010033 response to organic substance; GO:0071420 cellular response to histamine; GO:0043312 neutrophil degranulation; GO:0035372 protein localization to microtubule; GO:0002263 cell activation involved in immune response; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0043933 macromolecular complex subunit organization; GO:0002366 leukocyte activation involved in immune response; GO:0070727 cellular macromolecule localization; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:0034765 regulation of ion transmembrane transport; GO:0071495 cellular response to endogenous stimulus; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0010522 regulation of calcium ion transport into cytosol; GO:0001775 cell activation; GO:0007605 sensory perception of sound; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0006955 immune response; GO:0040012 regulation of locomotion; GO:0050793 regulation of developmental process; GO:0022604 regulation of cell morphogenesis; GO:0006887 exocytosis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0032587 ruffle membrane; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0072686 mitotic spindle; GO:0005815 microtubule organizing center; GO:0098590 plasma membrane region; GO:0015630 microtubule cytoskeleton; GO:0031256 leading edge membrane; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0099503 secretory vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0097708 intracellular vesicle; GO:0031252 cell leading edge; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0070820 tertiary granule; GO:0044446 intracellular organelle part; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0044463 cell projection part; GO:0005829 cytosol; GO:0005819 spindle; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0030667 secretory granule membrane; GO:0044459 plasma membrane part; GO:0101003 ficolin-1-rich granule membrane; GO:0001726 ruffle; GO:0031253 cell projection membrane; GO:0044444 cytoplasmic part; ","GO:0031267 small GTPase binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0017048 Rho GTPase binding; GO:0003723 RNA binding; GO:0008092 cytoskeletal protein binding; GO:0017016 Ras GTPase binding; GO:0005102 receptor binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0003779 actin binding; GO:0044325 ion channel binding; GO:0005515 protein binding; GO:0051020 GTPase binding; GO:0019899 enzyme binding; ","K05740","DIAPH1; diaphanous 1","hsa04510 Focal adhesion - Homo sapiens (human); hsa04933 AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human); hsa05131 Shigellosis - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); ","IPR010473; IPR010472; IPR015425; IPR010465; IPR014767; IPR014768; IPR016024; IPR009408; ","\"Formin, GTPase-binding domain; Formin, FH3 domain; Formin, FH2 domain; DRF autoregulatory; Diaphanous autoregulatory (DAD) domain; Rho GTPase-binding/formin homology 3 (GBD/FH3) domain; Armadillo-type fold; Formin Homology 1; \"\r"]
["O60613","Selenoprotein F OS=Homo sapiens OX=9606 GN=SELENOF","SELENOF",18.092,20.84,24.8,3,5,3,1.039,1.036,0.984,0.971,0.98,1.001,0.965,0.149,"extracellular\r","GO:0006457 protein folding; GO:0006458 'de novo' protein folding; GO:0051084 'de novo' posttranslational protein folding; GO:0009987 cellular process; ","GO:0005788 endoplasmic reticulum lumen; GO:0043229 intracellular organelle; GO:0005783 endoplasmic reticulum; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0070013 intracellular organelle lumen; GO:0044432 endoplasmic reticulum part; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0008430 selenium binding; GO:0005488 binding; ",{"$nulls":3},"IPR012336; ","Thioredoxin-like fold; \r"]
["O60664","Perilipin-3 OS=Homo sapiens OX=9606 GN=PLIN3","PLIN3",47.074,205.07,54.1,17,31,17,1,0.993,1.013,1.011,1.026,0.989,1.007,0.619,"cytoplasm\r","GO:0006810 transport; GO:0051179 localization; GO:0016192 vesicle-mediated transport; GO:0051234 establishment of localization; ","GO:0010008 endosome membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0016020 membrane; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044440 endosomal part; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005768 endosome; GO:0005811 lipid particle; GO:0005794 Golgi apparatus; GO:0030133 transport vesicle; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0050839 cell adhesion molecule binding; GO:0005515 protein binding; GO:0005488 binding; GO:0045296 cadherin binding; ","K20287"]
["O60669","Monocarboxylate transporter 2 OS=Homo sapiens OX=9606 GN=SLC16A7","SLC16A7",52.2,8.4574,7.3,4,4,4,1.223,1.134,1.1,0.875,0.909,0.79,0.745,0.00486,"plasma membrane\r","GO:0015850 organic hydroxy compound transport; GO:0034220 ion transmembrane transport; GO:0044699 single-organism process; GO:0071702 organic substance transport; GO:0046942 carboxylic acid transport; GO:0015727 lactate transport; GO:0015849 organic acid transport; GO:0098656 anion transmembrane transport; GO:0051234 establishment of localization; GO:0006810 transport; GO:0006820 anion transport; GO:0055085 transmembrane transport; GO:0015711 organic anion transport; GO:1902578 single-organism localization; GO:1903825 organic acid transmembrane transport; GO:0015718 monocarboxylic acid transport; GO:0006811 ion transport; GO:0035873 lactate transmembrane transport; GO:1901475 pyruvate transmembrane transport; GO:0051179 localization; GO:0006848 pyruvate transport; GO:1905039 carboxylic acid transmembrane transport; GO:0044765 single-organism transport; ","GO:0016020 membrane; GO:0031226 intrinsic component of plasma membrane; GO:0044459 plasma membrane part; GO:0044425 membrane part; GO:0044464 cell part; GO:0071944 cell periphery; GO:0031224 intrinsic component of membrane; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; ","GO:0022804 active transmembrane transporter activity; GO:0015291 secondary active transmembrane transporter activity; GO:0005342 organic acid transmembrane transporter activity; GO:0015075 ion transmembrane transporter activity; GO:0015293 symporter activity; GO:1901618 organic hydroxy compound transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0015129 lactate transmembrane transporter activity; GO:0008028 monocarboxylic acid transmembrane transporter activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0005477 pyruvate secondary active transmembrane transporter activity; GO:0050833 pyruvate transmembrane transporter activity; GO:0008514 organic anion transmembrane transporter activity; GO:0008509 anion transmembrane transporter activity; GO:0046943 carboxylic acid transmembrane transporter activity; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; ","K08184",null,null,"IPR020846; ","Major facilitator superfamily domain; \r"]
["O60684","Importin subunit alpha-7 OS=Homo sapiens OX=9606 GN=KPNA6","KPNA6",60.029,37.494,17.2,8,9,8,0.857,0.899,0.983,1.085,1.051,1.119,1.188,0.0169,"cyto_nucl\r","GO:0006607 NLS-bearing protein import into nucleus; GO:0072594 establishment of protein localization to organelle; GO:0022414 reproductive process; GO:0017038 protein import; GO:0009891 positive regulation of biosynthetic process; GO:0044699 single-organism process; GO:0051169 nuclear transport; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:2001141 regulation of RNA biosynthetic process; GO:0051649 establishment of localization in cell; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0044706 multi-multicellular organism process; GO:0044702 single organism reproductive process; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0033365 protein localization to organelle; GO:0006606 protein import into nucleus; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0044765 single-organism transport; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0048522 positive regulation of cellular process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:1902582 single-organism intracellular transport; GO:0006810 transport; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006913 nucleocytoplasmic transport; GO:0048609 multicellular organismal reproductive process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0000003 reproduction; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0060135 maternal process involved in female pregnancy; GO:0060255 regulation of macromolecule metabolic process; GO:1902593 single-organism nuclear import; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0007565 female pregnancy; GO:1902578 single-organism localization; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0006886 intracellular protein transport; GO:0044744 protein targeting to nucleus; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902580 single-organism cellular localization; GO:1902680 positive regulation of RNA biosynthetic process; GO:0034613 cellular protein localization; GO:0051254 positive regulation of RNA metabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0071702 organic substance transport; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0032504 multicellular organism reproduction; GO:0070727 cellular macromolecule localization; GO:0051170 nuclear import; GO:0031325 positive regulation of cellular metabolic process; GO:0044703 multi-organism reproductive process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0051179 localization; GO:0034504 protein localization to nucleus; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005643 nuclear pore; GO:0005635 nuclear envelope; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0031975 envelope; GO:0043227 membrane-bounded organelle; GO:0043234 protein complex; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005048 signal sequence binding; GO:0008565 protein transporter activity; GO:0042277 peptide binding; GO:0005488 binding; GO:0008139 nuclear localization sequence binding; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0033218 amide binding; GO:0005215 transporter activity; ",{"$nulls":3},"IPR002652; IPR011989; IPR016024; ","\"Importin-alpha, importin-beta-binding domain; Armadillo-like helical; Armadillo-type fold; \"\r"]
["O60701","UDP-glucose 6-dehydrogenase OS=Homo sapiens OX=9606 GN=UGDH","UGDH",55.023,88.275,30,12,15,12,0.985,1.015,0.957,1.017,1.001,1.041,1.034,0.171,"cytoplasm\r","GO:0009226 nucleotide-sugar biosynthetic process; GO:0044707 single-multicellular organism process; GO:0016053 organic acid biosynthetic process; GO:0046398 UDP-glucuronate metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0006024 glycosaminoglycan biosynthetic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:0030203 glycosaminoglycan metabolic process; GO:0071704 organic substance metabolic process; GO:0007369 gastrulation; GO:0009653 anatomical structure morphogenesis; GO:0001702 gastrulation with mouth forming second; GO:0008152 metabolic process; GO:0006011 UDP-glucose metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0007275 multicellular organism development; GO:0009059 macromolecule biosynthetic process; GO:0009790 embryo development; GO:0006022 aminoglycan metabolic process; GO:0009987 cellular process; GO:0048598 embryonic morphogenesis; GO:0032502 developmental process; GO:0018130 heterocycle biosynthetic process; GO:0006023 aminoglycan biosynthetic process; GO:0006065 UDP-glucuronate biosynthetic process; GO:0044711 single-organism biosynthetic process; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0032501 multicellular organismal process; GO:0044249 cellular biosynthetic process; GO:0046394 carboxylic acid biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0044767 single-organism developmental process; GO:0044283 small molecule biosynthetic process; GO:0019752 carboxylic acid metabolic process; GO:0009225 nucleotide-sugar metabolic process; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:1901362 organic cyclic compound biosynthetic process; GO:0043436 oxoacid metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0000166 nucleotide binding; GO:0048037 cofactor binding; GO:0016491 oxidoreductase activity; GO:0009055 electron carrier activity; GO:0016614 oxidoreductase activity, acting on CH-OH group of donors; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; GO:0003979 UDP-glucose 6-dehydrogenase activity; GO:0003824 catalytic activity; GO:0051287 NAD binding; GO:0005488 binding; GO:0050662 coenzyme binding; GO:0036094 small molecule binding; ","K00012","UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]","hsa00053 Ascorbate and aldarate metabolism - Homo sapiens (human); hsa00040 Pentose and glucuronate interconversions - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00520 Amino sugar and nucleotide sugar metabolism - Homo sapiens (human); ","IPR001732; IPR008927; IPR016040; IPR014027; IPR014026; ","\"UDP-glucose/GDP-mannose dehydrogenase, N-terminal; 6-phosphogluconate dehydrogenase C-terminal domain-like; NAD(P)-binding domain; UDP-glucose/GDP-mannose dehydrogenase, C-terminal; UDP-glucose/GDP-mannose dehydrogenase, dimerisation; \"\r"]
["O60711","Leupaxin OS=Homo sapiens OX=9606 GN=LPXN","LPXN",43.332,2.5796,3.4,1,1,1,0.963,0.909,1.015,0.894,1.196,1.018,1.077,0.494,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0009968 negative regulation of signal transduction; GO:0097659 nucleic acid-templated transcription; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0050858 negative regulation of antigen receptor-mediated signaling pathway; GO:0050855 regulation of B cell receptor signaling pathway; GO:0044237 cellular metabolic process; GO:0022610 biological adhesion; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0007155 cell adhesion; GO:0043170 macromolecule metabolic process; GO:0010468 regulation of gene expression; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0071822 protein complex subunit organization; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0023052 signaling; GO:0050776 regulation of immune response; GO:0002683 negative regulation of immune system process; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0002682 regulation of immune system process; GO:0070271 protein complex biogenesis; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0007162 negative regulation of cell adhesion; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0050854 regulation of antigen receptor-mediated signaling pathway; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0050859 negative regulation of B cell receptor signaling pathway; GO:0009059 macromolecule biosynthetic process; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0006355 regulation of transcription, DNA-templated; GO:0033628 regulation of cell adhesion mediated by integrin; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0044238 primary metabolic process; GO:0051252 regulation of RNA metabolic process; GO:1901576 organic substance biosynthetic process; GO:0030155 regulation of cell adhesion; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0010467 gene expression; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005925 focal adhesion; GO:0016607 nuclear speck; GO:0044464 cell part; GO:0005622 intracellular; GO:0005912 adherens junction; GO:0048471 perinuclear region of cytoplasm; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0005924 cell-substrate adherens junction; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0031981 nuclear lumen; GO:0002102 podosome; GO:0005829 cytosol; GO:0015629 actin cytoskeleton; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0046914 transition metal ion binding; GO:0005488 binding; GO:0043167 ion binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0003712 transcription cofactor activity; GO:0008270 zinc ion binding; GO:0000988 transcription factor activity, protein binding; ",{"$nulls":3},"IPR001781; ","\"Zinc finger, LIM-type; \"\r"]
["O60716","Catenin delta-1 OS=Homo sapiens OX=9606 GN=CTNND1","CTNND1",108.17,119.47,25.1,21,27,21,0.92,0.984,0.91,1.045,1.072,1.04,1.122,0.0116,"nucleus\r","GO:0044700 single organism signaling; GO:0044409 entry into host; GO:0009968 negative regulation of signal transduction; GO:0007166 cell surface receptor signaling pathway; GO:0097659 nucleic acid-templated transcription; GO:0007420 brain development; GO:0023051 regulation of signaling; GO:0045216 cell-cell junction organization; GO:0090090 negative regulation of canonical Wnt signaling pathway; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0022610 biological adhesion; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0016337 single organismal cell-cell adhesion; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0034332 adherens junction organization; GO:0007155 cell adhesion; GO:0060322 head development; GO:0043170 macromolecule metabolic process; GO:0016055 Wnt signaling pathway; GO:0044419 interspecies interaction between organisms; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0030178 negative regulation of Wnt signaling pathway; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0098609 cell-cell adhesion; GO:1901360 organic cyclic compound metabolic process; GO:0060828 regulation of canonical Wnt signaling pathway; GO:0032774 RNA biosynthetic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0023052 signaling; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0198738 cell-cell signaling by wnt; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0030260 entry into host cell; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0007267 cell-cell signaling; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0007417 central nervous system development; GO:0051828 entry into other organism involved in symbiotic interaction; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0098602 single organism cell adhesion; GO:0019222 regulation of metabolic process; GO:0048856 anatomical structure development; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0051806 entry into cell of other organism involved in symbiotic interaction; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0023057 negative regulation of signaling; GO:0035635 entry of bacterium into host cell; GO:0046483 heterocycle metabolic process; GO:0010648 negative regulation of cell communication; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0009966 regulation of signal transduction; GO:0006355 regulation of transcription, DNA-templated; GO:0048731 system development; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0044238 primary metabolic process; GO:0051701 interaction with host; GO:1901576 organic substance biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0034330 cell junction organization; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0030111 regulation of Wnt signaling pathway; GO:0044767 single-organism developmental process; GO:0010467 gene expression; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0030425 dendrite; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0030426 growth cone; GO:0044424 intracellular part; GO:0005913 cell-cell adherens junction; GO:0005911 cell-cell junction; GO:0005623 cell; GO:0043197 dendritic spine; GO:0070062 extracellular exosome; GO:0044309 neuron spine; GO:0005622 intracellular; GO:0044464 cell part; GO:0030027 lamellipodium; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0044456 synapse part; GO:0031252 cell leading edge; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0070161 anchoring junction; GO:0030496 midbody; GO:0030427 site of polarized growth; GO:0044463 cell projection part; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043296 apical junction complex; GO:0045202 synapse; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0036477 somatodendritic compartment; GO:0098794 postsynapse; GO:0005915 zonula adherens; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0050839 cell adhesion molecule binding; GO:0005102 receptor binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0019901 protein kinase binding; GO:0005515 protein binding; GO:0019900 kinase binding; GO:0019899 enzyme binding; ","K05690","CTNND1; catenin (cadherin-associated protein), delta 1","hsa04670 Leukocyte transendothelial migration - Homo sapiens (human); hsa04015 Rap1 signaling pathway - Homo sapiens (human); hsa04520 Adherens junction - Homo sapiens (human); ","IPR011989; IPR016024; ","Armadillo-like helical; Armadillo-type fold; \r"]
["O60749","Sorting nexin-2 OS=Homo sapiens OX=9606 GN=SNX2","SNX2",58.47,42.936,20.6,11,17,9,1.008,1.074,1.043,0.982,0.947,0.93,0.915,0.0217,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0097581 lamellipodium organization; GO:0048869 cellular developmental process; GO:0048193 Golgi vesicle transport; GO:0032989 cellular component morphogenesis; GO:0044699 single-organism process; GO:0015031 protein transport; GO:0072673 lamellipodium morphogenesis; GO:0051259 protein oligomerization; GO:0051234 establishment of localization; GO:0009653 anatomical structure morphogenesis; GO:0051649 establishment of localization in cell; GO:0022607 cellular component assembly; GO:0032990 cell part morphogenesis; GO:0065003 macromolecular complex assembly; GO:0006886 intracellular protein transport; GO:0048858 cell projection morphogenesis; GO:0016482 cytosolic transport; GO:0034613 cellular protein localization; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0032502 developmental process; GO:0071822 protein complex subunit organization; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0016050 vesicle organization; GO:0071702 organic substance transport; GO:0006897 endocytosis; GO:0051641 cellular localization; GO:0043933 macromolecular complex subunit organization; GO:0016197 endosomal transport; GO:0000902 cell morphogenesis; GO:0006810 transport; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0034498 early endosome to Golgi transport; GO:0042147 retrograde transport, endosome to Golgi; GO:0030030 cell projection organization; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0051179 localization; GO:0070271 protein complex biogenesis; GO:0048856 anatomical structure development; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0030904 retromer complex; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0019898 extrinsic component of membrane; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0098805 whole membrane; GO:0005764 lysosome; GO:0030027 lamellipodium; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0031901 early endosome membrane; GO:0043227 membrane-bounded organelle; GO:0000323 lytic vacuole; GO:0010008 endosome membrane; GO:0043229 intracellular organelle; GO:0031252 cell leading edge; GO:0097708 intracellular vesicle; GO:0042995 cell projection; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0044440 endosomal part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005773 vacuole; GO:0030905 retromer, tubulation complex; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0046982 protein heterodimerization activity; GO:0005102 receptor binding; GO:0046983 protein dimerization activity; GO:0043167 ion binding; GO:0044877 macromolecular complex binding; GO:0070851 growth factor receptor binding; GO:0005515 protein binding; GO:1990460 leptin receptor binding; GO:0005158 insulin receptor binding; GO:0050839 cell adhesion molecule binding; GO:0042802 identical protein binding; GO:0005154 epidermal growth factor receptor binding; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0045296 cadherin binding; GO:0005543 phospholipid binding; GO:0035091 phosphatidylinositol binding; GO:0008289 lipid binding; GO:0043168 anion binding; GO:1990459 transferrin receptor binding; GO:0032403 protein complex binding; ","K17917","SNX1_2; sorting nexin-1/2","hsa04144 Endocytosis - Homo sapiens (human); ","IPR015404; IPR005329; IPR001683; ","\"Sorting nexin Vps5-like, C-terminal; Sorting nexin, N-terminal; Phox homologous domain; \"\r"]
["O60762","Dolichol-phosphate mannosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=DPM1","DPM1",29.634,5.7603,10,3,5,3,1.13,1.037,1.082,0.956,0.919,0.896,0.853,0.00698,"nucleus\r","GO:0043413 macromolecule glycosylation; GO:0046486 glycerolipid metabolic process; GO:0006066 alcohol metabolic process; GO:0006643 membrane lipid metabolic process; GO:0008654 phospholipid biosynthetic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044255 cellular lipid metabolic process; GO:0018196 peptidyl-asparagine modification; GO:0044237 cellular metabolic process; GO:0042157 lipoprotein metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0008610 lipid biosynthetic process; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0006650 glycerophospholipid metabolic process; GO:0046488 phosphatidylinositol metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006487 protein N-linked glycosylation; GO:0042158 lipoprotein biosynthetic process; GO:0006629 lipid metabolic process; GO:0006486 protein glycosylation; GO:0009101 glycoprotein biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006664 glycolipid metabolic process; GO:0009100 glycoprotein metabolic process; GO:0090407 organophosphate biosynthetic process; GO:0044710 single-organism metabolic process; GO:0046474 glycerophospholipid biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0006497 protein lipidation; GO:0006493 protein O-linked glycosylation; GO:0036211 protein modification process; GO:0006506 GPI anchor biosynthetic process; GO:0009247 glycolipid biosynthetic process; GO:1903509 liposaccharide metabolic process; GO:1901615 organic hydroxy compound metabolic process; GO:0006661 phosphatidylinositol biosynthetic process; GO:0044267 cellular protein metabolic process; GO:0071704 organic substance metabolic process; GO:0035268 protein mannosylation; GO:0006505 GPI anchor metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0035269 protein O-linked mannosylation; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0046467 membrane lipid biosynthetic process; GO:0070085 glycosylation; GO:0097502 mannosylation; GO:0006720 isoprenoid metabolic process; GO:0044711 single-organism biosynthetic process; GO:0019348 dolichol metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0045017 glycerolipid biosynthetic process; GO:0016093 polyprenol metabolic process; GO:0018193 peptidyl-amino acid modification; GO:0018279 protein N-linked glycosylation via asparagine; GO:0034645 cellular macromolecule biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0019637 organophosphate metabolic process; GO:0006644 phospholipid metabolic process; GO:0043412 macromolecule modification; ","GO:0031501 mannosyltransferase complex; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:1990234 transferase complex; GO:0005623 cell; GO:0033185 dolichol-phosphate-mannose synthase complex; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:1902494 catalytic complex; GO:0005634 nucleus; GO:0044432 endoplasmic reticulum part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; ","GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity; GO:0016758 transferase activity, transferring hexosyl groups; GO:0000030 mannosyltransferase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity; GO:0016757 transferase activity, transferring glycosyl groups; GO:0005515 protein binding; GO:0016740 transferase activity; ","K00721","DPM1; dolichol-phosphate mannosyltransferase [EC:2.4.1.83]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00510 N-Glycan biosynthesis - Homo sapiens (human); ","IPR029044; IPR001173; ","Nucleotide-diphospho-sugar transferases; Glycosyltransferase 2-like; \r"]
["O60763","General vesicular transport factor p115 OS=Homo sapiens OX=9606 GN=USO1","USO1",107.89,117.55,22.5,18,26,18,1.026,0.985,1.034,0.997,0.968,0.972,0.965,0.111,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0051640 organelle localization; GO:0090174 organelle membrane fusion; GO:0016043 cellular component organization; GO:0006901 vesicle coating; GO:0046907 intracellular transport; GO:0010256 endomembrane system organization; GO:0048207 vesicle targeting, rough ER to cis-Golgi; GO:0048208 COPII vesicle coating; GO:0044699 single-organism process; GO:0048193 Golgi vesicle transport; GO:0048280 vesicle fusion with Golgi apparatus; GO:0006903 vesicle targeting; GO:0022406 membrane docking; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0051649 establishment of localization in cell; GO:1902578 single-organism localization; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0051648 vesicle localization; GO:0048199 vesicle targeting, to, from or within Golgi; GO:0006886 intracellular protein transport; GO:0034613 cellular protein localization; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0044801 single-organism membrane fusion; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0044765 single-organism transport; GO:0051650 establishment of vesicle localization; GO:0071822 protein complex subunit organization; GO:0090114 COPII-coated vesicle budding; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0044802 single-organism membrane organization; GO:0061025 membrane fusion; GO:0016050 vesicle organization; GO:0071702 organic substance transport; GO:0048284 organelle fusion; GO:0048278 vesicle docking; GO:0051656 establishment of organelle localization; GO:0043933 macromolecular complex subunit organization; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:1902589 single-organism organelle organization; GO:0070727 cellular macromolecule localization; GO:0048211 Golgi vesicle docking; GO:0007030 Golgi organization; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0006900 membrane budding; GO:0006906 vesicle fusion; GO:0051179 localization; GO:0070271 protein complex biogenesis; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0045056 transcytosis; GO:0071840 cellular component organization or biogenesis; ","GO:0030658 transport vesicle membrane; GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0030662 coated vesicle membrane; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0098791 Golgi subcompartment; GO:0048471 perinuclear region of cytoplasm; GO:0044431 Golgi apparatus part; GO:0043227 membrane-bounded organelle; GO:0012507 ER to Golgi transport vesicle membrane; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012506 vesicle membrane; GO:0030134 ER to Golgi transport vesicle; GO:0012505 endomembrane system; GO:0005795 Golgi stack; GO:0031981 nuclear lumen; GO:0044452 nucleolar part; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0030135 coated vesicle; GO:0001650 fibrillar center; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0030133 transport vesicle; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; GO:0031984 organelle subcompartment; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0050839 cell adhesion molecule binding; GO:0003723 RNA binding; GO:0008565 protein transporter activity; GO:0005488 binding; GO:0045296 cadherin binding; GO:0003676 nucleic acid binding; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0005215 transporter activity; ",{"$nulls":3},"IPR006955; IPR016024; IPR006953; ","\"Uso1/p115-like vesicle tethering protein, C-terminal; Armadillo-type fold; Vesicle tethering protein Uso1/P115-like , head domain; \"\r"]
["O60784","Target of Myb protein 1 OS=Homo sapiens OX=9606 GN=TOM1","TOM1",53.818,41.1,18.7,6,9,6,0.943,1.034,1.001,0.994,0.934,1.071,1.007,0.904,"cytoplasm\r","GO:0046907 intracellular transport; GO:0045321 leukocyte activation; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0051649 establishment of localization in cell; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0006886 intracellular protein transport; GO:0036230 granulocyte activation; GO:0034613 cellular protein localization; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0009987 cellular process; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0002274 myeloid leukocyte activation; GO:0002443 leukocyte mediated immunity; GO:0016192 vesicle-mediated transport; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0071702 organic substance transport; GO:0002376 immune system process; GO:0006897 endocytosis; GO:0043312 neutrophil degranulation; GO:0002263 cell activation involved in immune response; GO:0002444 myeloid leukocyte mediated immunity; GO:0051641 cellular localization; GO:0016197 endosomal transport; GO:0045184 establishment of protein localization; GO:0002366 leukocyte activation involved in immune response; GO:0006810 transport; GO:0070727 cellular macromolecule localization; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0032940 secretion by cell; GO:0001775 cell activation; GO:0043299 leukocyte degranulation; GO:0006955 immune response; GO:0051179 localization; GO:0006887 exocytosis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0070062 extracellular exosome; GO:0005765 lysosomal membrane; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0035579 specific granule membrane; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0035577 azurophil granule membrane; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0042582 azurophil granule; GO:0098852 lytic vacuole membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0030667 secretory granule membrane; GO:0005766 primary lysosome; GO:0042581 specific granule; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0030276 clathrin binding; GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR002014; IPR004152; IPR008942; ","VHS domain; GAT domain; ENTH/VHS; \r"]
["O60826","Coiled-coil domain-containing protein 22 OS=Homo sapiens OX=9606 GN=CCDC22","CCDC22",70.755,43.514,15.2,8,9,8,0.952,1.059,0.96,1.014,1.004,1.041,1.03,0.446,"cytoplasm\r","GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0009968 negative regulation of signal transduction; GO:1903533 regulation of protein targeting; GO:0031331 positive regulation of cellular catabolic process; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0090317 negative regulation of intracellular protein transport; GO:0044699 single-organism process; GO:0015031 protein transport; GO:0042308 negative regulation of protein import into nucleus; GO:0051234 establishment of localization; GO:0031396 regulation of protein ubiquitination; GO:1903364 positive regulation of cellular protein catabolic process; GO:0042306 regulation of protein import into nucleus; GO:0010646 regulation of cell communication; GO:0009893 positive regulation of metabolic process; GO:0032879 regulation of localization; GO:0006893 Golgi to plasma membrane transport; GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling; GO:0055065 metal ion homeostasis; GO:0032387 negative regulation of intracellular transport; GO:1900181 negative regulation of protein localization to nucleus; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0051651 maintenance of location in cell; GO:1903362 regulation of cellular protein catabolic process; GO:0046823 negative regulation of nucleocytoplasmic transport; GO:0051051 negative regulation of transport; GO:0051220 cytoplasmic sequestering of protein; GO:0042994 cytoplasmic sequestering of transcription factor; GO:1903828 negative regulation of cellular protein localization; GO:0006878 cellular copper ion homeostasis; GO:0032507 maintenance of protein location in cell; GO:0042992 negative regulation of transcription factor import into nucleus; GO:0050801 ion homeostasis; GO:0080090 regulation of primary metabolic process; GO:0042345 regulation of NF-kappaB import into nucleus; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0098771 inorganic ion homeostasis; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0019725 cellular homeostasis; GO:0032386 regulation of intracellular transport; GO:0031323 regulation of cellular metabolic process; GO:0046916 cellular transition metal ion homeostasis; GO:0006810 transport; GO:2000058 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:1902532 negative regulation of intracellular signal transduction; GO:0048583 regulation of response to stimulus; GO:1900180 regulation of protein localization to nucleus; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0051223 regulation of protein transport; GO:0042347 negative regulation of NF-kappaB import into nucleus; GO:0050794 regulation of cellular process; GO:0055076 transition metal ion homeostasis; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:0060255 regulation of macromolecule metabolic process; GO:0007253 cytoplasmic sequestering of NF-kappaB; GO:0031399 regulation of protein modification process; GO:0030003 cellular cation homeostasis; GO:0048193 Golgi vesicle transport; GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:1904589 regulation of protein import; GO:1904590 negative regulation of protein import; GO:0055082 cellular chemical homeostasis; GO:0070201 regulation of establishment of protein localization; GO:0060341 regulation of cellular localization; GO:0042990 regulation of transcription factor import into nucleus; GO:0042592 homeostatic process; GO:1903322 positive regulation of protein modification by small protein conjugation or removal; GO:0045862 positive regulation of proteolysis; GO:0023057 negative regulation of signaling; GO:1902578 single-organism localization; GO:0010648 negative regulation of cell communication; GO:0055080 cation homeostasis; GO:0023056 positive regulation of signaling; GO:0009896 positive regulation of catabolic process; GO:0042176 regulation of protein catabolic process; GO:0010647 positive regulation of cell communication; GO:0051235 maintenance of location; GO:0032880 regulation of protein localization; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0009966 regulation of signal transduction; GO:0033157 regulation of intracellular protein transport; GO:0048878 chemical homeostasis; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:1902531 regulation of intracellular signal transduction; GO:0098876 vesicle-mediated transport to the plasma membrane; GO:0045185 maintenance of protein location; GO:0051224 negative regulation of protein transport; GO:0051049 regulation of transport; GO:0016192 vesicle-mediated transport; GO:0031401 positive regulation of protein modification process; GO:0071702 organic substance transport; GO:0030162 regulation of proteolysis; GO:0048585 negative regulation of response to stimulus; GO:0048518 positive regulation of biological process; GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0055070 copper ion homeostasis; GO:0070727 cellular macromolecule localization; GO:0051247 positive regulation of protein metabolic process; GO:0031398 positive regulation of protein ubiquitination; GO:0046822 regulation of nucleocytoplasmic transport; GO:0006873 cellular ion homeostasis; GO:0051246 regulation of protein metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling; GO:1904950 negative regulation of establishment of protein localization; GO:0006875 cellular metal ion homeostasis; GO:0045732 positive regulation of protein catabolic process; GO:0009967 positive regulation of signal transduction; GO:0048584 positive regulation of response to stimulus; GO:0006892 post-Golgi vesicle-mediated transport; GO:0051179 localization; GO:1903827 regulation of cellular protein localization; GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process; GO:0065007 biological regulation; ","GO:0043226 organelle; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0031410 cytoplasmic vesicle; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0005768 endosome; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0097602 cullin family protein binding; GO:0005488 binding; "]
["O60830","Mitochondrial import inner membrane translocase subunit Tim17-B OS=Homo sapiens OX=9606 GN=TIMM17B","TIMM17B",18.273,35.758,12.8,1,1,1,1.044,0.952,0.963,1.072,0.932,1.048,1.031,0.597,"plasma membrane\r","GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0072594 establishment of protein localization to organelle; GO:0017038 protein import; GO:0006839 mitochondrial transport; GO:0044699 single-organism process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0051649 establishment of localization in cell; GO:1902578 single-organism localization; GO:1990542 mitochondrial transmembrane transport; GO:0007005 mitochondrion organization; GO:0065002 intracellular protein transmembrane transport; GO:0006886 intracellular protein transport; GO:0006626 protein targeting to mitochondrion; GO:1902580 single-organism cellular localization; GO:0033365 protein localization to organelle; GO:0044743 protein transmembrane import into intracellular organelle; GO:0034613 cellular protein localization; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0009987 cellular process; GO:0044765 single-organism transport; GO:0030150 protein import into mitochondrial matrix; GO:0071806 protein transmembrane transport; GO:0071702 organic substance transport; GO:0070585 protein localization to mitochondrion; GO:1902582 single-organism intracellular transport; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:0055085 transmembrane transport; GO:0070727 cellular macromolecule localization; GO:0006996 organelle organization; GO:0051179 localization; GO:0072655 establishment of protein localization to mitochondrion; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0031305 integral component of mitochondrial inner membrane; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0005744 mitochondrial inner membrane presequence translocase complex; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0031304 intrinsic component of mitochondrial inner membrane; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0031301 integral component of organelle membrane; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0043229 intracellular organelle; GO:0098573 intrinsic component of mitochondrial membrane; GO:0044429 mitochondrial part; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0016021 integral component of membrane; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031975 envelope; GO:0032592 integral component of mitochondrial membrane; GO:0043234 protein complex; GO:0031966 mitochondrial membrane; GO:0031300 intrinsic component of organelle membrane; GO:0044444 cytoplasmic part; ","GO:0022804 active transmembrane transporter activity; GO:0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity; GO:0008565 protein transporter activity; GO:0022884 macromolecule transmembrane transporter activity; GO:0015399 primary active transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0008320 protein transmembrane transporter activity; GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0022857 transmembrane transporter activity; GO:0005215 transporter activity; ","K17795"]
["O60832","H/ACA ribonucleoprotein complex subunit 4 OS=Homo sapiens OX=9606 GN=DKC1","DKC1",57.673,13.001,7,3,4,3,0.919,0.991,0.948,1.045,1.059,1.04,1.1,0.0132,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0022613 ribonucleoprotein complex biogenesis; GO:0051973 positive regulation of telomerase activity; GO:0010608 posttranscriptional regulation of gene expression; GO:0043489 RNA stabilization; GO:0009891 positive regulation of biosynthetic process; GO:1904816 positive regulation of protein localization to chromosome, telomeric region; GO:0032204 regulation of telomere maintenance; GO:0009451 RNA modification; GO:0044237 cellular metabolic process; GO:0043628 ncRNA 3'-end processing; GO:1904851 positive regulation of establishment of protein localization to telomere; GO:0008152 metabolic process; GO:0006364 rRNA processing; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:1904874 positive regulation of telomerase RNA localization to Cajal body; GO:0043170 macromolecule metabolic process; GO:0051347 positive regulation of transferase activity; GO:0031118 rRNA pseudouridine synthesis; GO:0006396 RNA processing; GO:0018130 heterocycle biosynthetic process; GO:0051054 positive regulation of DNA metabolic process; GO:0080090 regulation of primary metabolic process; GO:0042254 ribosome biogenesis; GO:0090669 telomerase RNA stabilization; GO:0031323 regulation of cellular metabolic process; GO:0050790 regulation of catalytic activity; GO:2001252 positive regulation of chromosome organization; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0032200 telomere organization; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0006259 DNA metabolic process; GO:0000154 rRNA modification; GO:0032844 regulation of homeostatic process; GO:0060249 anatomical structure homeostasis; GO:0043487 regulation of RNA stability; GO:0060341 regulation of cellular localization; GO:1904356 regulation of telomere maintenance via telomere lengthening; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0016073 snRNA metabolic process; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0032880 regulation of protein localization; GO:1904872 regulation of telomerase RNA localization to Cajal body; GO:0001522 pseudouridine synthesis; GO:1904814 regulation of protein localization to chromosome, telomeric region; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0008283 cell proliferation; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:2000278 regulation of DNA biosynthetic process; GO:0033044 regulation of chromosome organization; GO:0043144 snoRNA processing; GO:0051276 chromosome organization; GO:1904951 positive regulation of establishment of protein localization; GO:0006996 organelle organization; GO:0032206 positive regulation of telomere maintenance; GO:0031325 positive regulation of cellular metabolic process; GO:0051972 regulation of telomerase activity; GO:0031120 snRNA pseudouridine synthesis; GO:0043412 macromolecule modification; GO:0031328 positive regulation of cellular biosynthetic process; GO:1903827 regulation of cellular protein localization; GO:0000723 telomere maintenance; GO:0044699 single-organism process; GO:0010833 telomere maintenance via telomere lengthening; GO:0009058 biosynthetic process; GO:0051130 positive regulation of cellular component organization; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0032846 positive regulation of homeostatic process; GO:0034470 ncRNA processing; GO:0016072 rRNA metabolic process; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0032212 positive regulation of telomere maintenance via telomerase; GO:0016070 RNA metabolic process; GO:0040031 snRNA modification; GO:0050789 regulation of biological process; GO:0051052 regulation of DNA metabolic process; GO:0090304 nucleic acid metabolic process; GO:0010638 positive regulation of organelle organization; GO:1990481 mRNA pseudouridine synthesis; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0033979 box H/ACA snoRNA metabolic process; GO:0070202 regulation of establishment of protein localization to chromosome; GO:0031123 RNA 3'-end processing; GO:0032210 regulation of telomere maintenance via telomerase; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:1903829 positive regulation of cellular protein localization; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0000495 box H/ACA snoRNA 3'-end processing; GO:0070201 regulation of establishment of protein localization; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0034964 box H/ACA snoRNA processing; GO:0034641 cellular nitrogen compound metabolic process; GO:0071897 DNA biosynthetic process; GO:0031126 snoRNA 3'-end processing; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0016556 mRNA modification; GO:1904358 positive regulation of telomere maintenance via telomere lengthening; GO:0006807 nitrogen compound metabolic process; GO:0033043 regulation of organelle organization; GO:0010556 regulation of macromolecule biosynthetic process; GO:0007004 telomere maintenance via telomerase; GO:0016074 snoRNA metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0043085 positive regulation of catalytic activity; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0070203 regulation of establishment of protein localization to telomere; GO:0010467 gene expression; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0051128 regulation of cellular component organization; GO:0034660 ncRNA metabolic process; GO:2000573 positive regulation of DNA biosynthetic process; GO:0006278 RNA-dependent DNA biosynthetic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0005737 cytoplasm; GO:0031429 box H/ACA snoRNP complex; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0015030 Cajal body; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0072588 box H/ACA RNP complex; GO:0043227 membrane-bounded organelle; GO:0005697 telomerase holoenzyme complex; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044452 nucleolar part; GO:0005730 nucleolus; GO:0001650 fibrillar center; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0072589 box H/ACA scaRNP complex; GO:0005732 small nucleolar ribonucleoprotein complex; GO:0090661 box H/ACA telomerase RNP complex; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0044428 nuclear part; ","GO:0003723 RNA binding; GO:0003720 telomerase activity; GO:0003964 RNA-directed DNA polymerase activity; GO:0005515 protein binding; GO:0009982 pseudouridine synthase activity; GO:0070034 telomerase RNA binding; GO:1901363 heterocyclic compound binding; GO:0030515 snoRNA binding; GO:0097159 organic cyclic compound binding; GO:0016853 isomerase activity; GO:0016779 nucleotidyltransferase activity; GO:0003824 catalytic activity; GO:0034513 box H/ACA snoRNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0034061 DNA polymerase activity; GO:0016740 transferase activity; GO:0016866 intramolecular transferase activity; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K11131","DKC1; H/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]","hsa03008 Ribosome biogenesis in eukaryotes - Homo sapiens (human); ","IPR020103; IPR015947; IPR002478; IPR032819; IPR004521; IPR012960; IPR002501; ","\"Pseudouridine synthase, catalytic domain; PUA-like domain; PUA domain; tRNA pseudouridylate synthase B, C-terminal; Uncharacterised domain CHP00451; Dyskerin-like; Pseudouridine synthase II, N-terminal; \"\r"]
["O60841","Eukaryotic translation initiation factor 5B OS=Homo sapiens OX=9606 GN=EIF5B","EIF5B",138.83,22.095,5.2,7,8,7,0.886,0.911,0.906,1.083,1.086,1.1,1.209,4.05e-05,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0006518 peptide metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0010608 posttranscriptional regulation of gene expression; GO:0044267 cellular protein metabolic process; GO:0009058 biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0009889 regulation of biosynthetic process; GO:0006413 translational initiation; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006412 translation; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0043043 peptide biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0043603 cellular amide metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0034248 regulation of cellular amide metabolic process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0051246 regulation of protein metabolic process; GO:0006417 regulation of translation; GO:0044260 cellular macromolecule metabolic process; GO:0006446 regulation of translational initiation; GO:0019222 regulation of metabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0065007 biological regulation; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0003743 translation initiation factor activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0003924 GTPase activity; GO:0043169 cation binding; GO:0043168 anion binding; GO:0019001 guanyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003723 RNA binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0008135 translation factor activity, RNA binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003676 nucleic acid binding; GO:0046872 metal ion binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0032561 guanyl ribonucleotide binding; GO:0036094 small molecule binding; ","K03243","EIF5B; translation initiation factor 5B","hsa03013 RNA transport - Homo sapiens (human); ","IPR023115; IPR005225; IPR004161; IPR027417; IPR000795; IPR009000; ","\"Translation initiation factor IF- 2, domain 3; Small GTP-binding protein domain; Translation elongation factor EFTu-like, domain 2; P-loop containing nucleoside triphosphate hydrolase; Transcription factor, GTP-binding domain; Translation protein, beta-barrel domain; \"\r"]
["O60861","Growth arrest-specific protein 7 OS=Homo sapiens OX=9606 GN=GAS7","GAS7",54.371,7.0717,6.9,3,3,3,0.945,1.017,0.947,1.037,1.082,0.979,1.065,0.172,"nucleus\r","GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0045786 negative regulation of cell cycle; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:2001141 regulation of RNA biosynthetic process; GO:0030154 cell differentiation; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0051726 regulation of cell cycle; GO:0009987 cellular process; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0010468 regulation of gene expression; GO:0006355 regulation of transcription, DNA-templated; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0007050 cell cycle arrest; GO:0048731 system development; GO:0044763 single-organism cellular process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0051252 regulation of RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0044767 single-organism developmental process; GO:0019222 regulation of metabolic process; GO:0022402 cell cycle process; GO:0048856 anatomical structure development; GO:0007049 cell cycle; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0065007 biological regulation; ","GO:0044424 intracellular part; GO:0005623 cell; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; ","GO:0005515 protein binding; GO:0003700 transcription factor activity, sequence-specific DNA binding; GO:0005488 binding; GO:0001071 nucleic acid binding transcription factor activity; ","K18618",null,null,"IPR001452; IPR031160; IPR001202; IPR001060; ","SH3 domain; F-BAR domain; WW domain; FCH domain; \r"]
["O60879","Protein diaphanous homolog 2 OS=Homo sapiens OX=9606 GN=DIAPH2","DIAPH2",125.57,6.1042,3.2,4,4,4,1.12,0.939,1.025,0.943,1.044,0.939,0.949,0.452,"nucleus\r","GO:0000003 reproduction; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0022414 reproductive process; GO:0007292 female gamete generation; GO:0048869 cellular developmental process; GO:0007015 actin filament organization; GO:0044699 single-organism process; GO:0048468 cell development; GO:0030036 actin cytoskeleton organization; GO:0030154 cell differentiation; GO:0000910 cytokinesis; GO:0044702 single organism reproductive process; GO:0007281 germ cell development; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0032502 developmental process; GO:0003006 developmental process involved in reproduction; GO:0048477 oogenesis; GO:0019953 sexual reproduction; GO:0044763 single-organism cellular process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0007276 gamete generation; GO:0032504 multicellular organism reproduction; GO:1902589 single-organism organelle organization; GO:0044767 single-organism developmental process; GO:0006996 organelle organization; GO:0044703 multi-organism reproductive process; GO:0022412 cellular process involved in reproduction in multicellular organism; GO:0030029 actin filament-based process; GO:0051301 cell division; GO:0022402 cell cycle process; GO:0097435 supramolecular fiber organization; GO:0048609 multicellular organismal reproductive process; GO:0048856 anatomical structure development; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; ","GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0031982 vesicle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0031267 small GTPase binding; GO:0017048 Rho GTPase binding; GO:0008092 cytoskeletal protein binding; GO:0005102 receptor binding; GO:0017016 Ras GTPase binding; GO:0005488 binding; GO:0003779 actin binding; GO:0005515 protein binding; GO:0051020 GTPase binding; GO:0019899 enzyme binding; ","K05741","DIAPH2; diaphanous 2","hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); ","IPR014767; IPR010473; IPR010472; IPR014768; IPR015425; IPR016024; IPR010465; ","\"Diaphanous autoregulatory (DAD) domain; Formin, GTPase-binding domain; Formin, FH3 domain; Rho GTPase-binding/formin homology 3 (GBD/FH3) domain; Formin, FH2 domain; Armadillo-type fold; DRF autoregulatory; \"\r"]
["O60884","DnaJ homolog subfamily A member 2 OS=Homo sapiens OX=9606 GN=DNAJA2","DNAJA2",45.745,29.144,16.5,6,9,6,0.874,0.904,0.889,1.165,1.125,1.04,1.249,0.0032,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0042127 regulation of cell proliferation; GO:0006950 response to stress; GO:0009628 response to abiotic stimulus; GO:0048522 positive regulation of cellular process; GO:0050896 response to stimulus; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0006457 protein folding; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:0051345 positive regulation of hydrolase activity; GO:0043462 regulation of ATPase activity; GO:0009408 response to heat; GO:0050790 regulation of catalytic activity; GO:0009266 response to temperature stimulus; GO:0044093 positive regulation of molecular function; GO:0065009 regulation of molecular function; GO:0032781 positive regulation of ATPase activity; GO:0009987 cellular process; GO:0042026 protein refolding; GO:0008284 positive regulation of cell proliferation; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0008047 enzyme activator activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0031072 heat shock protein binding; GO:0051087 chaperone binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0001671 ATPase activator activity; GO:0030234 enzyme regulator activity; GO:0046872 metal ion binding; GO:0032555 purine ribonucleotide binding; GO:0051082 unfolded protein binding; GO:0001883 purine nucleoside binding; GO:0060590 ATPase regulator activity; GO:0036094 small molecule binding; ","K09503","DNAJA2; DnaJ homolog subfamily A member 2","hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); ","IPR008971; IPR002939; IPR001623; IPR001305; ","\"HSP40/DnaJ peptide-binding; Chaperone DnaJ, C-terminal; DnaJ domain; Heat shock protein DnaJ, cysteine-rich domain; \"\r"]
["O60888","Protein CutA OS=Homo sapiens OX=9606 GN=CUTA","CUTA",19.116,10.5,15.6,2,3,2,1.096,1.029,1.044,0.975,0.932,0.941,0.899,0.0105,"extracellular\r","GO:0042221 response to chemical; GO:0010035 response to inorganic substance; GO:0033036 macromolecule localization; GO:0051179 localization; GO:0008104 protein localization; GO:0050896 response to stimulus; GO:0010038 response to metal ion; ","GO:0016020 membrane; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:0046914 transition metal ion binding; GO:0005488 binding; GO:0043167 ion binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0005507 copper ion binding; GO:0019899 enzyme binding; ","K03926",null,null,"IPR011322; ","\"Nitrogen regulatory PII-like, alpha/beta; \"\r"]
["O60911","Cathepsin L2 OS=Homo sapiens OX=9606 GN=CTSV","CTSV",37.329,9.8466,9.3,3,6,3,0.91,0.893,1.011,0.958,1.126,1.094,1.129,0.128,"extracellular\r","GO:0010837 regulation of keratinocyte proliferation; GO:0022414 reproductive process; GO:0008584 male gonad development; GO:0009749 response to glucose; GO:0044237 cellular metabolic process; GO:0008285 negative regulation of cell proliferation; GO:0046697 decidualization; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0050678 regulation of epithelial cell proliferation; GO:0044706 multi-multicellular organism process; GO:0044702 single organism reproductive process; GO:0048545 response to steroid hormone; GO:0008544 epidermis development; GO:0009719 response to endogenous stimulus; GO:0051493 regulation of cytoskeleton organization; GO:0009743 response to carbohydrate; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0007399 nervous system development; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0043588 skin development; GO:0003006 developmental process involved in reproduction; GO:0019953 sexual reproduction; GO:0044763 single-organism cellular process; GO:0060008 Sertoli cell differentiation; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0098773 skin epidermis development; GO:1901575 organic substance catabolic process; GO:0048513 animal organ development; GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; GO:0030163 protein catabolic process; GO:0034284 response to monosaccharide; GO:0044260 cellular macromolecule metabolic process; GO:0021675 nerve development; GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II; GO:0048609 multicellular organismal reproductive process; GO:0001942 hair follicle development; GO:0030855 epithelial cell differentiation; GO:0050794 regulation of cellular process; GO:0000003 reproduction; GO:0002009 morphogenesis of an epithelium; GO:0033554 cellular response to stress; GO:0044707 single-multicellular organism process; GO:0060135 maternal process involved in female pregnancy; GO:0009267 cellular response to starvation; GO:0042127 regulation of cell proliferation; GO:0001890 placenta development; GO:0042303 molting cycle; GO:0032956 regulation of actin cytoskeleton organization; GO:1990834 response to odorant; GO:1901700 response to oxygen-containing compound; GO:0044267 cellular protein metabolic process; GO:0008406 gonad development; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0009653 anatomical structure morphogenesis; GO:0007565 female pregnancy; GO:0043062 extracellular structure organization; GO:0044248 cellular catabolic process; GO:0007548 sex differentiation; GO:0007275 multicellular organism development; GO:0061458 reproductive system development; GO:0006950 response to stress; GO:0007283 spermatogenesis; GO:0048731 system development; GO:0002376 immune system process; GO:0032970 regulation of actin filament-based process; GO:0071496 cellular response to external stimulus; GO:0022405 hair cycle process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0042633 hair cycle; GO:0048102 autophagic cell death; GO:0031668 cellular response to extracellular stimulus; GO:0012501 programmed cell death; GO:0046546 development of primary male sexual characteristics; GO:0009746 response to hexose; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0016485 protein processing; GO:0001893 maternal placenta development; GO:0048729 tissue morphogenesis; GO:0007154 cell communication; GO:0022404 molting cycle process; GO:0022617 extracellular matrix disassembly; GO:0030198 extracellular matrix organization; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0032502 developmental process; GO:0010259 multicellular organism aging; GO:0060429 epithelium development; GO:0009888 tissue development; GO:0048002 antigen processing and presentation of peptide antigen; GO:0048608 reproductive structure development; GO:0002495 antigen processing and presentation of peptide antigen via MHC class II; GO:0051384 response to glucocorticoid; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0007568 aging; GO:0050680 negative regulation of epithelial cell proliferation; GO:0048856 anatomical structure development; GO:0010839 negative regulation of keratinocyte proliferation; GO:0016043 cellular component organization; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0046661 male sex differentiation; GO:0048730 epidermis morphogenesis; GO:0050896 response to stimulus; GO:0031669 cellular response to nutrient levels; GO:0071704 organic substance metabolic process; GO:0034698 response to gonadotropin; GO:0009991 response to extracellular stimulus; GO:0016540 protein autoprocessing; GO:0033993 response to lipid; GO:0030154 cell differentiation; GO:2000249 regulation of actin cytoskeleton reorganization; GO:0031960 response to corticosteroid; GO:0006508 proteolysis; GO:0031069 hair follicle morphogenesis; GO:0009987 cellular process; GO:0045137 development of primary sexual characteristics; GO:0044265 cellular macromolecule catabolic process; GO:0048232 male gamete generation; GO:0033043 regulation of organelle organization; GO:0007276 gamete generation; GO:0032504 multicellular organism reproduction; GO:0019882 antigen processing and presentation; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0009057 macromolecule catabolic process; GO:0044703 multi-organism reproductive process; GO:0022411 cellular component disassembly; GO:0042594 response to starvation; GO:0010467 gene expression; GO:0031667 response to nutrient levels; GO:0051128 regulation of cellular component organization; GO:0051604 protein maturation; GO:0009725 response to hormone; GO:0009056 catabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0009897 external side of plasma membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0043025 neuronal cell body; GO:0044424 intracellular part; GO:0098858 actin-based cell projection; GO:0005623 cell; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0045177 apical part of cell; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0098552 side of membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0005730 nucleolus; GO:0043202 lysosomal lumen; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0036477 somatodendritic compartment; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0044437 vacuolar part; GO:0005902 microvillus; GO:0043204 perikaryon; GO:0005773 vacuole; GO:0044297 cell body; GO:0009986 cell surface; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0004180 carboxypeptidase activity; GO:0042393 histone binding; GO:0008238 exopeptidase activity; GO:0008233 peptidase activity; GO:0044877 macromolecular complex binding; GO:0008236 serine-type peptidase activity; GO:0004177 aminopeptidase activity; GO:0016787 hydrolase activity; GO:0008234 cysteine-type peptidase activity; GO:0005515 protein binding; GO:0033218 amide binding; GO:0004252 serine-type endopeptidase activity; GO:0004175 endopeptidase activity; GO:0017171 serine hydrolase activity; GO:0003824 catalytic activity; GO:0042277 peptide binding; GO:0005488 binding; GO:0030984 kininogen binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0016807 cysteine-type carboxypeptidase activity; GO:0004197 cysteine-type endopeptidase activity; GO:0070004 cysteine-type exopeptidase activity; GO:0032403 protein complex binding; ","K01375","CTSL2; cathepsin V [EC:3.4.22.43]","hsa04142 Lysosome - Homo sapiens (human); hsa04210 Apoptosis - Homo sapiens (human); ","IPR013201; IPR000668; ","\"Cathepsin propeptide inhibitor domain (I29); Peptidase C1A, papain C-terminal; \"\r"]
["O60925","Prefoldin subunit 1 OS=Homo sapiens OX=9606 GN=PFDN1","PFDN1",14.21,8.2572,23,3,6,3,1.003,0.973,1.023,0.982,1.002,1.023,1.003,0.891,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0010468 regulation of gene expression; GO:0006355 regulation of transcription, DNA-templated; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0006457 protein folding; GO:2001141 regulation of RNA biosynthetic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0019222 regulation of metabolic process; GO:0009987 cellular process; GO:0007049 cell cycle; GO:0065007 biological regulation; GO:2000112 regulation of cellular macromolecule biosynthetic process; ","GO:0016272 prefoldin complex; GO:0032991 macromolecular complex; GO:0043234 protein complex; ","GO:0005515 protein binding; GO:0051082 unfolded protein binding; GO:0003700 transcription factor activity, sequence-specific DNA binding; GO:0044183 protein binding involved in protein folding; GO:0005488 binding; GO:0001071 nucleic acid binding transcription factor activity; ","K09548"]
["O60936","Nucleolar protein 3 OS=Homo sapiens OX=9606 GN=NOL3","NOL3",22.629,7.9334,9.1,1,1,1,0.904,0.96,1.067,1.079,0.984,1.01,1.048,0.429,"cyto_nucl\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0010941 regulation of cell death; GO:0022613 ribonucleoprotein complex biogenesis; GO:0014745 negative regulation of muscle adaptation; GO:0022618 ribonucleoprotein complex assembly; GO:1903533 regulation of protein targeting; GO:0090201 negative regulation of release of cytochrome c from mitochondria; GO:1903318 negative regulation of protein maturation; GO:0010821 regulation of mitochondrion organization; GO:0044237 cellular metabolic process; GO:0010466 negative regulation of peptidase activity; GO:0008152 metabolic process; GO:0032879 regulation of localization; GO:0065003 macromolecular complex assembly; GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling; GO:0010658 striated muscle cell apoptotic process; GO:0060402 calcium ion transport into cytosol; GO:0055065 metal ion homeostasis; GO:0044057 regulation of system process; GO:0090559 regulation of membrane permeability; GO:0043170 macromolecule metabolic process; GO:0044765 single-organism transport; GO:0052548 regulation of endopeptidase activity; GO:0014808 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; GO:0006396 RNA processing; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0031323 regulation of cellular metabolic process; GO:0043086 negative regulation of catalytic activity; GO:0032501 multicellular organismal process; GO:0006874 cellular calcium ion homeostasis; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0006810 transport; GO:0010660 regulation of muscle cell apoptotic process; GO:1902532 negative regulation of intracellular signal transduction; GO:0080135 regulation of cellular response to stress; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0060759 regulation of response to cytokine stimulus; GO:0048583 regulation of response to stimulus; GO:1903202 negative regulation of oxidative stress-induced cell death; GO:0044260 cellular macromolecule metabolic process; GO:0051223 regulation of protein transport; GO:1903317 regulation of protein maturation; GO:0060548 negative regulation of cell death; GO:0016071 mRNA metabolic process; GO:0098662 inorganic cation transmembrane transport; GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0010951 negative regulation of endopeptidase activity; GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway; GO:0034220 ion transmembrane transport; GO:0097190 apoptotic signaling pathway; GO:0007006 mitochondrial membrane organization; GO:0030001 metal ion transport; GO:0009628 response to abiotic stimulus; GO:0010955 negative regulation of protein processing; GO:0043067 regulation of programmed cell death; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0010665 regulation of cardiac muscle cell apoptotic process; GO:0032844 regulation of homeostatic process; GO:0051239 regulation of multicellular organismal process; GO:0042990 regulation of transcription factor import into nucleus; GO:0060341 regulation of cellular localization; GO:0051259 protein oligomerization; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0023057 negative regulation of signaling; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0010648 negative regulation of cell communication; GO:0006139 nucleobase-containing compound metabolic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0001974 blood vessel remodeling; GO:0070482 response to oxygen levels; GO:0032880 regulation of protein localization; GO:0008380 RNA splicing; GO:0009966 regulation of signal transduction; GO:0051209 release of sequestered calcium ion into cytosol; GO:0048878 chemical homeostasis; GO:0006461 protein complex assembly; GO:0070588 calcium ion transmembrane transport; GO:0045861 negative regulation of proteolysis; GO:0010823 negative regulation of mitochondrion organization; GO:1902531 regulation of intracellular signal transduction; GO:0051282 regulation of sequestering of calcium ion; GO:0006950 response to stress; GO:2001237 negative regulation of extrinsic apoptotic signaling pathway; GO:1902656 calcium ion import into cytosol; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0014735 regulation of muscle atrophy; GO:1900408 negative regulation of cellular response to oxidative stress; GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process; GO:0055085 transmembrane transport; GO:0060761 negative regulation of response to cytokine stimulus; GO:0043502 regulation of muscle adaptation; GO:0046822 regulation of nucleocytoplasmic transport; GO:0006873 cellular ion homeostasis; GO:0006811 ion transport; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0070613 regulation of protein processing; GO:1902882 regulation of response to oxidative stress; GO:0036293 response to decreased oxygen levels; GO:0012501 programmed cell death; GO:0007204 positive regulation of cytosolic calcium ion concentration; GO:0051179 localization; GO:0000245 spliceosomal complex assembly; GO:1903827 regulation of cellular protein localization; GO:0097340 inhibition of cysteine-type endopeptidase activity; GO:0070838 divalent metal ion transport; GO:0014874 response to stimulus involved in regulation of muscle adaptation; GO:0010659 cardiac muscle cell apoptotic process; GO:0072503 cellular divalent inorganic cation homeostasis; GO:0009968 negative regulation of signal transduction; GO:0090199 regulation of release of cytochrome c from mitochondria; GO:0023051 regulation of signaling; GO:0051129 negative regulation of cellular component organization; GO:0006839 mitochondrial transport; GO:0044699 single-organism process; GO:0051241 negative regulation of multicellular organismal process; GO:0010657 muscle cell apoptotic process; GO:0051234 establishment of localization; GO:0009611 response to wounding; GO:0002931 response to ischemia; GO:2001233 regulation of apoptotic signaling pathway; GO:0042306 regulation of protein import into nucleus; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0010646 regulation of cell communication; GO:2001243 negative regulation of intrinsic apoptotic signaling pathway; GO:0071826 ribonucleoprotein complex subunit organization; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0006915 apoptotic process; GO:0007005 mitochondrion organization; GO:0014736 negative regulation of muscle atrophy; GO:0060401 cytosolic calcium ion transport; GO:0010468 regulation of gene expression; GO:0098655 cation transmembrane transport; GO:0097553 calcium ion transmembrane import into cytosol; GO:0071822 protein complex subunit organization; GO:0050801 ion homeostasis; GO:2000116 regulation of cysteine-type endopeptidase activity; GO:0042345 regulation of NF-kappaB import into nucleus; GO:0055074 calcium ion homeostasis; GO:0014876 response to injury involved in regulation of muscle adaptation; GO:0060547 negative regulation of necrotic cell death; GO:0098771 inorganic ion homeostasis; GO:0019725 cellular homeostasis; GO:1901360 organic cyclic compound metabolic process; GO:0032386 regulation of intracellular transport; GO:0090257 regulation of muscle system process; GO:0023052 signaling; GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:0010639 negative regulation of organelle organization; GO:1902589 single-organism organelle organization; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:1902883 negative regulation of response to oxidative stress; GO:0090304 nucleic acid metabolic process; GO:2001236 regulation of extrinsic apoptotic signaling pathway; GO:1900180 regulation of protein localization to nucleus; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0070509 calcium ion import; GO:0052547 regulation of peptidase activity; GO:0070271 protein complex biogenesis; GO:0072507 divalent inorganic cation homeostasis; GO:0006376 mRNA splice site selection; GO:0016043 cellular component organization; GO:0010667 negative regulation of cardiac muscle cell apoptotic process; GO:0072511 divalent inorganic cation transport; GO:0043069 negative regulation of programmed cell death; GO:2000021 regulation of ion homeostasis; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway; GO:0030003 cellular cation homeostasis; GO:0051480 regulation of cytosolic calcium ion concentration; GO:0001959 regulation of cytokine-mediated signaling pathway; GO:1903201 regulation of oxidative stress-induced cell death; GO:0031324 negative regulation of cellular metabolic process; GO:1904589 regulation of protein import; GO:0050896 response to stimulus; GO:0097193 intrinsic apoptotic signaling pathway; GO:0051346 negative regulation of hydrolase activity; GO:0070201 regulation of establishment of protein localization; GO:0055082 cellular chemical homeostasis; GO:0001960 negative regulation of cytokine-mediated signaling pathway; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0000398 mRNA splicing, via spliceosome; GO:0046902 regulation of mitochondrial membrane permeability; GO:0006812 cation transport; GO:0006816 calcium ion transport; GO:0055080 cation homeostasis; GO:0043066 negative regulation of apoptotic process; GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process; GO:0001666 response to hypoxia; GO:2000117 negative regulation of cysteine-type endopeptidase activity; GO:0070296 sarcoplasmic reticulum calcium ion transport; GO:0034641 cellular nitrogen compound metabolic process; GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0033157 regulation of intracellular protein transport; GO:0009987 cellular process; GO:0010939 regulation of necrotic cell death; GO:0048771 tissue remodeling; GO:0034622 cellular macromolecular complex assembly; GO:0035795 negative regulation of mitochondrial membrane permeability; GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway; GO:0008637 apoptotic mitochondrial changes; GO:0010629 negative regulation of gene expression; GO:0098660 inorganic ion transmembrane transport; GO:0035556 intracellular signal transduction; GO:0051049 regulation of transport; GO:0010664 negative regulation of striated muscle cell apoptotic process; GO:0006807 nitrogen compound metabolic process; GO:0033043 regulation of organelle organization; GO:0044802 single-organism membrane organization; GO:0032845 negative regulation of homeostatic process; GO:0048585 negative regulation of response to stimulus; GO:0051283 negative regulation of sequestering of calcium ion; GO:0010656 negative regulation of muscle cell apoptotic process; GO:0051641 cellular localization; GO:0043933 macromolecular complex subunit organization; GO:1902176 negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway; GO:0010662 regulation of striated muscle cell apoptotic process; GO:1900407 regulation of cellular response to oxidative stress; GO:0008219 cell death; GO:0051246 regulation of protein metabolic process; GO:1903514 calcium ion transport from endoplasmic reticulum to cytosol; GO:1905709 negative regulation of membrane permeability; GO:2001242 regulation of intrinsic apoptotic signaling pathway; GO:0051248 negative regulation of protein metabolic process; GO:0006875 cellular metal ion homeostasis; GO:0010467 gene expression; GO:0051128 regulation of cellular component organization; GO:0097341 zymogen inhibition; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0016529 sarcoplasmic reticulum; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0005623 cell; GO:0016528 sarcoplasm; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0003723 RNA binding; GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process; GO:0032813 tumor necrosis factor receptor superfamily binding; GO:0005102 receptor binding; GO:0005126 cytokine receptor binding; GO:0043167 ion binding; GO:0061134 peptidase regulator activity; GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process; GO:0005515 protein binding; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0004866 endopeptidase inhibitor activity; GO:0004869 cysteine-type endopeptidase inhibitor activity; GO:0035877 death effector domain binding; GO:0002020 protease binding; GO:0089720 caspase binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0042802 identical protein binding; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0030414 peptidase inhibitor activity; GO:0003676 nucleic acid binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0061135 endopeptidase regulator activity; GO:0019904 protein domain specific binding; GO:0005509 calcium ion binding; GO:0005123 death receptor binding; GO:0019899 enzyme binding; ",{"$nulls":3},"IPR011029; IPR001315; ","Death-like domain; CARD domain; \r"]
["O75027","ATP-binding cassette sub-family B member 7, mitochondrial OS=Homo sapiens OX=9606 GN=ABCB7","ABCB7",82.64,3.0056,1.3,1,1,1,1.109,0.878,0.938,0.93,1.149,0.998,1.052,0.609,"plasma membrane\r","GO:0006879 cellular iron ion homeostasis; GO:0065008 regulation of biological quality; GO:0055076 transition metal ion homeostasis; GO:0030003 cellular cation homeostasis; GO:0055072 iron ion homeostasis; GO:0044699 single-organism process; GO:0055082 cellular chemical homeostasis; GO:0051234 establishment of localization; GO:0042592 homeostatic process; GO:1902578 single-organism localization; GO:0015886 heme transport; GO:0055080 cation homeostasis; GO:0055065 metal ion homeostasis; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0044765 single-organism transport; GO:0050801 ion homeostasis; GO:0051181 cofactor transport; GO:0044763 single-organism cellular process; GO:0098771 inorganic ion homeostasis; GO:0019725 cellular homeostasis; GO:0071702 organic substance transport; GO:0046916 cellular transition metal ion homeostasis; GO:0006810 transport; GO:0055085 transmembrane transport; GO:0006873 cellular ion homeostasis; GO:0006875 cellular metal ion homeostasis; GO:1901678 iron coordination entity transport; GO:0051179 localization; GO:0071705 nitrogen compound transport; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044429 mitochondrial part; GO:0031090 organelle membrane; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005740 mitochondrial envelope; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0031975 envelope; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0015232 heme transporter activity; GO:1901265 nucleoside phosphate binding; GO:0015399 primary active transmembrane transporter activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0051184 cofactor transporter activity; GO:0016887 ATPase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0043492 ATPase activity, coupled to movement of substances; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005215 transporter activity; GO:0022804 active transmembrane transporter activity; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity; GO:0042626 ATPase activity, coupled to transmembrane movement of substances; GO:0042623 ATPase activity, coupled; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0022857 transmembrane transporter activity; GO:0036094 small molecule binding; ","K05662","ABCB7; ATP-binding cassette, subfamily B (MDR/TAP), member 7","hsa02010 ABC transporters - Homo sapiens (human); ","IPR003593; IPR003439; IPR027417; IPR011527; ","\"AAA+ ATPase domain; ABC transporter-like; P-loop containing nucleoside triphosphate hydrolase; ABC transporter type 1, transmembrane domain; \"\r"]
["O75044","SLIT-ROBO Rho GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=SRGAP2","SRGAP2",120.87,11.459,4,4,4,4,0.99,1.116,0.987,0.979,0.874,1.068,0.944,0.452,"nucleus\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0046847 filopodium assembly; GO:0007420 brain development; GO:0032989 cellular component morphogenesis; GO:0021987 cerebral cortex development; GO:0021537 telencephalon development; GO:0022610 biological adhesion; GO:0034446 substrate adhesion-dependent cell spreading; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0021885 forebrain cell migration; GO:0021815 modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration; GO:0007155 cell adhesion; GO:0051056 regulation of small GTPase mediated signal transduction; GO:0007399 nervous system development; GO:0030032 lamellipodium assembly; GO:0051716 cellular response to stimulus; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0008347 glial cell migration; GO:0048812 neuron projection morphogenesis; GO:0048870 cell motility; GO:2000146 negative regulation of cell motility; GO:0032501 multicellular organismal process; GO:0050768 negative regulation of neurogenesis; GO:0000902 cell morphogenesis; GO:0000226 microtubule cytoskeleton organization; GO:0048513 animal organ development; GO:0022029 telencephalon cell migration; GO:0042063 gliogenesis; GO:0051336 regulation of hydrolase activity; GO:0007417 central nervous system development; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0098602 single organism cell adhesion; GO:0010721 negative regulation of cell development; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0031268 pseudopodium organization; GO:0051239 regulation of multicellular organismal process; GO:0009653 anatomical structure morphogenesis; GO:0051345 positive regulation of hydrolase activity; GO:2000145 regulation of cell motility; GO:0030900 forebrain development; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0009966 regulation of signal transduction; GO:1902531 regulation of intracellular signal transduction; GO:0051270 regulation of cellular component movement; GO:0021801 cerebral cortex radial glia guided migration; GO:0043547 positive regulation of GTPase activity; GO:0048731 system development; GO:0051960 regulation of nervous system development; GO:0060284 regulation of cell development; GO:0030334 regulation of cell migration; GO:0007017 microtubule-based process; GO:0030031 cell projection assembly; GO:0030182 neuron differentiation; GO:0060996 dendritic spine development; GO:0030336 negative regulation of cell migration; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0006928 movement of cell or subcellular component; GO:2001222 regulation of neuron migration; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0097581 lamellipodium organization; GO:0051093 negative regulation of developmental process; GO:0051674 localization of cell; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:0048666 neuron development; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0051241 negative regulation of multicellular organismal process; GO:0040013 negative regulation of locomotion; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0032990 cell part morphogenesis; GO:0048858 cell projection morphogenesis; GO:0060322 head development; GO:0045596 negative regulation of cell differentiation; GO:0032502 developmental process; GO:0023052 signaling; GO:0031269 pseudopodium assembly; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0030030 cell projection organization; GO:0001667 ameboidal-type cell migration; GO:0065009 regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0040011 locomotion; GO:0048856 anatomical structure development; GO:0051271 negative regulation of cellular component movement; GO:2000026 regulation of multicellular organismal development; GO:0021543 pallium development; GO:0016477 cell migration; GO:0016043 cellular component organization; GO:0021799 cerebral cortex radially oriented cell migration; GO:0016358 dendrite development; GO:0021795 cerebral cortex cell migration; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0000904 cell morphogenesis involved in differentiation; GO:0030154 cell differentiation; GO:0051961 negative regulation of nervous system development; GO:0003363 lamellipodium assembly involved in ameboidal cell migration; GO:0009987 cellular process; GO:0051014 actin filament severing; GO:0045595 regulation of cell differentiation; GO:0021814 cell motility involved in cerebral cortex radial glia guided migration; GO:0031175 neuron projection development; GO:0021816 extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration; GO:0043085 positive regulation of catalytic activity; GO:0031589 cell-substrate adhesion; GO:0044767 single-organism developmental process; GO:2001223 negative regulation of neuron migration; GO:0040012 regulation of locomotion; GO:0022030 telencephalon glial cell migration; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:0050767 regulation of neurogenesis; ","GO:0030425 dendrite; GO:0016020 membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0032279 asymmetric synapse; GO:0043197 dendritic spine; GO:0098590 plasma membrane region; GO:0044309 neuron spine; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0030027 lamellipodium; GO:0014069 postsynaptic density; GO:0097060 synaptic membrane; GO:0043005 neuron projection; GO:0030139 endocytic vesicle; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0098984 neuron to neuron synapse; GO:0044456 synapse part; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0031252 cell leading edge; GO:0042995 cell projection; GO:0045335 phagocytic vesicle; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0005886 plasma membrane; GO:0045202 synapse; GO:0045211 postsynaptic membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0036477 somatodendritic compartment; GO:0044459 plasma membrane part; GO:0098794 postsynapse; GO:0044327 dendritic spine head; GO:0099572 postsynaptic specialization; GO:0044444 cytoplasmic part; ","GO:0031267 small GTPase binding; GO:0017048 Rho GTPase binding; GO:0048365 Rac GTPase binding; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0030695 GTPase regulator activity; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0042802 identical protein binding; GO:0030234 enzyme regulator activity; GO:0017016 Ras GTPase binding; GO:0005488 binding; GO:0042803 protein homodimerization activity; GO:0051020 GTPase binding; GO:0019899 enzyme binding; GO:0008047 enzyme activator activity; GO:0005096 GTPase activator activity; ","K07526","SRGAP; SLIT-ROBO Rho GTPase activating protein","hsa04360 Axon guidance - Homo sapiens (human); ","IPR001452; IPR031160; IPR001060; IPR008936; IPR000198; ","SH3 domain; F-BAR domain; FCH domain; Rho GTPase activation protein; Rho GTPase-activating protein domain; \r"]
["O75083","WD repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=WDR1","WDR1",66.193,164.22,34.8,19,40,19,1.013,0.989,1.016,1.006,1.041,0.993,1.007,0.687,"cytoplasm\r","GO:0001738 morphogenesis of a polarized epithelium; GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0014013 regulation of gliogenesis; GO:0043243 positive regulation of protein complex disassembly; GO:0035088 establishment or maintenance of apical/basal cell polarity; GO:0032989 cellular component morphogenesis; GO:0030832 regulation of actin filament length; GO:0050877 neurological system process; GO:0030036 actin cytoskeleton organization; GO:0008360 regulation of cell shape; GO:0032879 regulation of localization; GO:0032535 regulation of cellular component size; GO:0030043 actin filament fragmentation; GO:0051493 regulation of cytoskeleton organization; GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0007399 nervous system development; GO:0048713 regulation of oligodendrocyte differentiation; GO:0002443 leukocyte mediated immunity; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0043269 regulation of ion transport; GO:0008154 actin polymerization or depolymerization; GO:0002520 immune system development; GO:0042247 establishment of planar polarity of follicular epithelium; GO:0007163 establishment or maintenance of cell polarity; GO:0048870 cell motility; GO:0007164 establishment of tissue polarity; GO:0032501 multicellular organismal process; GO:1901881 positive regulation of protein depolymerization; GO:0016333 morphogenesis of follicular epithelium; GO:0000902 cell morphogenesis; GO:0006810 transport; GO:0034762 regulation of transmembrane transport; GO:0048513 animal organ development; GO:0050900 leukocyte migration; GO:0055002 striated muscle cell development; GO:1902905 positive regulation of supramolecular fiber organization; GO:0035090 maintenance of apical/basal cell polarity; GO:0030834 regulation of actin filament depolymerization; GO:0097435 supramolecular fiber organization; GO:0045199 maintenance of epithelial cell apical/basal polarity; GO:1902903 regulation of supramolecular fiber organization; GO:0055001 muscle cell development; GO:0050794 regulation of cellular process; GO:0002009 morphogenesis of an epithelium; GO:0044707 single-multicellular organism process; GO:0032956 regulation of actin cytoskeleton organization; GO:0002576 platelet degranulation; GO:0051239 regulation of multicellular organismal process; GO:0009653 anatomical structure morphogenesis; GO:0097530 granulocyte migration; GO:1902578 single-organism localization; GO:0030239 myofibril assembly; GO:0061061 muscle structure development; GO:0043624 cellular protein complex disassembly; GO:0007275 multicellular organism development; GO:0061245 establishment or maintenance of bipolar cell polarity; GO:0007010 cytoskeleton organization; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0043297 apical junction assembly; GO:0051495 positive regulation of cytoskeleton organization; GO:0048731 system development; GO:0051960 regulation of nervous system development; GO:0060284 regulation of cell development; GO:1901879 regulation of protein depolymerization; GO:0016192 vesicle-mediated transport; GO:0010927 cellular component assembly involved in morphogenesis; GO:0032984 macromolecular complex disassembly; GO:0032970 regulation of actin filament-based process; GO:0002376 immune system process; GO:0045685 regulation of glial cell differentiation; GO:0008064 regulation of actin polymerization or depolymerization; GO:0045055 regulated exocytosis; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0006928 movement of cell or subcellular component; GO:0007605 sensory perception of sound; GO:0001736 establishment of planar polarity; GO:0060306 regulation of membrane repolarization; GO:0051179 localization; GO:0016334 establishment or maintenance of polarity of follicular epithelium; GO:0050793 regulation of developmental process; GO:0006887 exocytosis; GO:0051674 localization of cell; GO:0048869 cellular developmental process; GO:0045216 cell-cell junction organization; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0051234 establishment of localization; GO:0043241 protein complex disassembly; GO:1990266 neutrophil migration; GO:0051130 positive regulation of cellular component organization; GO:0048729 tissue morphogenesis; GO:0097529 myeloid leukocyte migration; GO:0022607 cellular component assembly; GO:0030011 maintenance of cell polarity; GO:0032502 developmental process; GO:0031032 actomyosin structure organization; GO:0030836 positive regulation of actin filament depolymerization; GO:0060429 epithelium development; GO:0007600 sensory perception; GO:0071822 protein complex subunit organization; GO:0009888 tissue development; GO:0002446 neutrophil mediated immunity; GO:0048522 positive regulation of cellular process; GO:0030220 platelet formation; GO:0030042 actin filament depolymerization; GO:0002444 myeloid leukocyte mediated immunity; GO:0042391 regulation of membrane potential; GO:1902589 single-organism organelle organization; GO:0045214 sarcomere organization; GO:0050789 regulation of biological process; GO:0010638 positive regulation of organelle organization; GO:0032940 secretion by cell; GO:0099623 regulation of cardiac muscle cell membrane repolarization; GO:0040011 locomotion; GO:0043244 regulation of protein complex disassembly; GO:0048856 anatomical structure development; GO:0050954 sensory perception of mechanical stimulus; GO:2000026 regulation of multicellular organismal development; GO:0016477 cell migration; GO:0016043 cellular component organization; GO:0034329 cell junction assembly; GO:0002252 immune effector process; GO:0007015 actin filament organization; GO:0030865 cortical cytoskeleton organization; GO:0048468 cell development; GO:0000904 cell morphogenesis involved in differentiation; GO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization; GO:0030154 cell differentiation; GO:0070925 organelle assembly; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0051261 protein depolymerization; GO:0051146 striated muscle cell differentiation; GO:0007043 cell-cell junction assembly; GO:0003008 system process; GO:0030099 myeloid cell differentiation; GO:0051049 regulation of transport; GO:0036344 platelet morphogenesis; GO:0033043 regulation of organelle organization; GO:0048518 positive regulation of biological process; GO:0048534 hematopoietic or lymphoid organ development; GO:0030097 hemopoiesis; GO:0043933 macromolecular complex subunit organization; GO:0034765 regulation of ion transmembrane transport; GO:0034330 cell junction organization; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0042692 muscle cell differentiation; GO:0022411 cellular component disassembly; GO:0090066 regulation of anatomical structure size; GO:0051128 regulation of cellular component organization; GO:0022604 regulation of cell morphogenesis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:0050767 regulation of neurogenesis; ","GO:0044421 extracellular region part; GO:0005938 cell cortex; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0031982 vesicle; GO:0099568 cytoplasmic region; GO:0005737 cytoplasm; GO:0030863 cortical cytoskeleton; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0030864 cortical actin cytoskeleton; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0005911 cell-cell junction; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005856 cytoskeleton; GO:0043209 myelin sheath; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0005884 actin filament; GO:0043227 membrane-bounded organelle; GO:0042641 actomyosin; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0099513 polymeric cytoskeletal fiber; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0042643 actomyosin, actin portion; GO:0002102 podosome; GO:0005829 cytosol; GO:0015629 actin cytoskeleton; GO:0005576 extracellular region; GO:0099081 supramolecular polymer; GO:0043226 organelle; GO:0044448 cell cortex part; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0051015 actin filament binding; GO:0008092 cytoskeletal protein binding; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0003779 actin binding; GO:0005515 protein binding; GO:0032403 protein complex binding; ",{"$nulls":3},"IPR017986; IPR015943; IPR011045; ","\"WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain; Nitrous oxide reductase, N-terminal; \"\r"]
["O75094","Slit homolog 3 protein OS=Homo sapiens OX=9606 GN=SLIT3","SLIT3",167.71,9.7047,2.6,4,4,4,0.972,1.105,1.128,0.936,0.887,0.987,0.877,0.0799,"extracellular\r","GO:0044700 single organism signaling; GO:0022414 reproductive process; GO:0007166 cell surface receptor signaling pathway; GO:0032989 cellular component morphogenesis; GO:0008285 negative regulation of cell proliferation; GO:0001558 regulation of cell growth; GO:0009605 response to external stimulus; GO:0051414 response to cortisol; GO:0044702 single organism reproductive process; GO:0048545 response to steroid hormone; GO:0009719 response to endogenous stimulus; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0014070 response to organic cyclic compound; GO:0003006 developmental process involved in reproduction; GO:0016049 cell growth; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0048812 neuron projection morphogenesis; GO:0006935 chemotaxis; GO:0032501 multicellular organismal process; GO:0000902 cell morphogenesis; GO:0048846 axon extension involved in axon guidance; GO:0048513 animal organ development; GO:0035385 Roundabout signaling pathway; GO:0060759 regulation of response to cytokine stimulus; GO:0048583 regulation of response to stimulus; GO:0008585 female gonad development; GO:0009887 animal organ morphogenesis; GO:0042330 taxis; GO:0048609 multicellular organismal reproductive process; GO:0000003 reproduction; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0070100 negative regulation of chemokine-mediated signaling pathway; GO:0042127 regulation of cell proliferation; GO:0008406 gonad development; GO:1901700 response to oxygen-containing compound; GO:1990138 neuron projection extension; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0042698 ovulation cycle; GO:0022602 ovulation cycle process; GO:0046545 development of primary female sexual characteristics; GO:0009653 anatomical structure morphogenesis; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0007409 axonogenesis; GO:0007548 sex differentiation; GO:0007275 multicellular organism development; GO:0061458 reproductive system development; GO:0009966 regulation of signal transduction; GO:0050919 negative chemotaxis; GO:0048731 system development; GO:0060560 developmental growth involved in morphogenesis; GO:0010033 response to organic substance; GO:0009892 negative regulation of metabolic process; GO:0060761 negative regulation of response to cytokine stimulus; GO:0030182 neuron differentiation; GO:0097485 neuron projection guidance; GO:1902742 apoptotic process involved in development; GO:0006928 movement of cell or subcellular component; GO:0012501 programmed cell death; GO:0048589 developmental growth; GO:0040007 growth; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0046660 female sex differentiation; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0032990 cell part morphogenesis; GO:0006915 apoptotic process; GO:0048858 cell projection morphogenesis; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0045926 negative regulation of growth; GO:0048675 axon extension; GO:0048608 reproductive structure development; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051384 response to glucocorticoid; GO:0030308 negative regulation of cell growth; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0030030 cell projection organization; GO:0032870 cellular response to hormone stimulus; GO:0022412 cellular process involved in reproduction in multicellular organism; GO:0019222 regulation of metabolic process; GO:0040011 locomotion; GO:1902284 neuron projection extension involved in neuron projection guidance; GO:0048856 anatomical structure development; GO:0016043 cellular component organization; GO:0040008 regulation of growth; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0001959 regulation of cytokine-mediated signaling pathway; GO:0050896 response to stimulus; GO:0007411 axon guidance; GO:0048468 cell development; GO:0000904 cell morphogenesis involved in differentiation; GO:0001960 negative regulation of cytokine-mediated signaling pathway; GO:0033993 response to lipid; GO:0030154 cell differentiation; GO:0031960 response to corticosteroid; GO:0061364 apoptotic process involved in luteolysis; GO:0009987 cellular process; GO:0045137 development of primary sexual characteristics; GO:0001554 luteolysis; GO:0010629 negative regulation of gene expression; GO:0070099 regulation of chemokine-mediated signaling pathway; GO:0048585 negative regulation of response to stimulus; GO:0031175 neuron projection development; GO:0032504 multicellular organism reproduction; GO:0061564 axon development; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0048588 developmental cell growth; GO:0071495 cellular response to endogenous stimulus; GO:0048511 rhythmic process; GO:0051128 regulation of cellular component organization; GO:0009725 response to hormone; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; GO:1901654 response to ketone; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0044444 cytoplasmic part; ","GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0005509 calcium ion binding; GO:0048495 Roundabout binding; GO:0005102 receptor binding; GO:0005488 binding; GO:0043167 ion binding; ","K06850","SLIT3; slit 3","hsa04360 Axon guidance - Homo sapiens (human); ","IPR000483; IPR000372; IPR001881; IPR000742; IPR032675; IPR009030; IPR001791; IPR013320; IPR006207; ","\"Cysteine-rich flanking region, C-terminal; Leucine-rich repeat N-terminal domain; EGF-like calcium-binding domain; EGF-like domain; Leucine-rich repeat domain, L domain-like; Growth factor receptor cysteine-rich domain; Laminin G domain; Concanavalin A-like lectin/glucanase domain; Cystine knot, C-terminal; \"\r"]
["O75112","LIM domain-binding protein 3 OS=Homo sapiens OX=9606 GN=LDB3","LDB3",77.134,17.289,5.6,3,3,3,0.853,1.029,0.995,1.104,1.019,1.004,1.087,0.257,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0055001 muscle cell development; GO:0016043 cellular component organization; GO:0048869 cellular developmental process; GO:0032989 cellular component morphogenesis; GO:0044699 single-organism process; GO:0048468 cell development; GO:0009653 anatomical structure morphogenesis; GO:0030154 cell differentiation; GO:0030036 actin cytoskeleton organization; GO:0070925 organelle assembly; GO:0022607 cellular component assembly; GO:0030239 myofibril assembly; GO:0061061 muscle structure development; GO:0007010 cytoskeleton organization; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0009987 cellular process; GO:0032502 developmental process; GO:0051146 striated muscle cell differentiation; GO:0031032 actomyosin structure organization; GO:0044763 single-organism cellular process; GO:0010927 cellular component assembly involved in morphogenesis; GO:1902589 single-organism organelle organization; GO:0045214 sarcomere organization; GO:0055002 striated muscle cell development; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0030029 actin filament-based process; GO:0042692 muscle cell differentiation; GO:0048856 anatomical structure development; GO:0097435 supramolecular fiber organization; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0030016 myofibril; GO:0005737 cytoplasm; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0030018 Z disc; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0031674 I band; GO:0031143 pseudopodium; GO:0044422 organelle part; GO:0099081 supramolecular polymer; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0005856 cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0043292 contractile fiber; GO:0030017 sarcomere; GO:0048471 perinuclear region of cytoplasm; GO:0044449 contractile fiber part; GO:0044444 cytoplasmic part; ","GO:0019901 protein kinase binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0008270 zinc ion binding; GO:0019900 kinase binding; GO:0051371 muscle alpha-actinin binding; GO:0008092 cytoskeletal protein binding; GO:0046914 transition metal ion binding; GO:0005488 binding; GO:0042805 actinin binding; GO:0005080 protein kinase C binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0051393 alpha-actinin binding; GO:0019899 enzyme binding; ","K19867",null,null,"IPR001781; IPR006643; IPR001478; IPR031847; ","\"Zinc finger, LIM-type; Zasp-like motif; PDZ domain; Domain of unknown function DUF4749; \"\r"]
["O75113","NEDD4-binding protein 1 OS=Homo sapiens OX=9606 GN=N4BP1","N4BP1",100.38,2.8855,1.7,2,2,2,0.967,1.068,0.96,1.112,0.95,0.957,1.008,0.921,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0042177 negative regulation of protein catabolic process; GO:1903051 negative regulation of proteolysis involved in cellular protein catabolic process; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:0060255 regulation of macromolecule metabolic process; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0034644 cellular response to UV; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:1901799 negative regulation of proteasomal protein catabolic process; GO:0031400 negative regulation of protein modification process; GO:0031396 regulation of protein ubiquitination; GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0009895 negative regulation of catabolic process; GO:0009314 response to radiation; GO:0042176 regulation of protein catabolic process; GO:0009987 cellular process; GO:0071478 cellular response to radiation; GO:1903362 regulation of cellular protein catabolic process; GO:0031397 negative regulation of protein ubiquitination; GO:0051716 cellular response to stimulus; GO:0045861 negative regulation of proteolysis; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0071214 cellular response to abiotic stimulus; GO:0009416 response to light stimulus; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0030162 regulation of proteolysis; GO:1903363 negative regulation of cellular protein catabolic process; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0009892 negative regulation of metabolic process; GO:0071482 cellular response to light stimulus; GO:1903321 negative regulation of protein modification by small protein conjugation or removal; GO:0031330 negative regulation of cellular catabolic process; GO:0009411 response to UV; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0051246 regulation of protein metabolic process; GO:0061136 regulation of proteasomal protein catabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0019222 regulation of metabolic process; GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005730 nucleolus; GO:0005623 cell; GO:0016604 nuclear body; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005654 nucleoplasm; GO:0016605 PML body; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR021869; ","\"Ribonuclease Zc3h12a-like, NYN domain; \"\r"]
["O75116","Rho-associated protein kinase 2 OS=Homo sapiens OX=9606 GN=ROCK2","ROCK2",160.9,69.537,14,20,20,19,1.13,1.086,1.057,0.963,0.882,0.874,0.831,0.007,"nucleus\r","GO:0044700 single organism signaling; GO:0019079 viral genome replication; GO:0030335 positive regulation of cell migration; GO:0032270 positive regulation of cellular protein metabolic process; GO:0007166 cell surface receptor signaling pathway; GO:0090002 establishment of protein localization to plasma membrane; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0010594 regulation of endothelial cell migration; GO:0030036 actin cytoskeleton organization; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0045682 regulation of epidermis development; GO:0010824 regulation of centrosome duplication; GO:0032879 regulation of localization; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0051493 regulation of cytoskeleton organization; GO:0044419 interspecies interaction between organisms; GO:0090068 positive regulation of cell cycle process; GO:0008104 protein localization; GO:0014070 response to organic cyclic compound; GO:0035305 negative regulation of dephosphorylation; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0051174 regulation of phosphorus metabolic process; GO:0035507 regulation of myosin-light-chain-phosphatase activity; GO:2000810 regulation of bicellular tight junction assembly; GO:0072657 protein localization to membrane; GO:0010632 regulation of epithelial cell migration; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0007264 small GTPase mediated signal transduction; GO:0007009 plasma membrane organization; GO:0051272 positive regulation of cellular component movement; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:1901888 regulation of cell junction assembly; GO:0032501 multicellular organismal process; GO:1901343 negative regulation of vasculature development; GO:0051704 multi-organism process; GO:0071396 cellular response to lipid; GO:0032886 regulation of microtubule-based process; GO:0000226 microtubule cytoskeleton organization; GO:0030856 regulation of epithelial cell differentiation; GO:0006939 smooth muscle contraction; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0035304 regulation of protein dephosphorylation; GO:0044260 cellular macromolecule metabolic process; GO:2000114 regulation of establishment of cell polarity; GO:0010604 positive regulation of macromolecule metabolic process; GO:0045765 regulation of angiogenesis; GO:0006464 cellular protein modification process; GO:0039694 viral RNA genome replication; GO:0051301 cell division; GO:0048010 vascular endothelial growth factor receptor signaling pathway; GO:1902903 regulation of supramolecular fiber organization; GO:0046605 regulation of centrosome cycle; GO:0050794 regulation of cellular process; GO:0016310 phosphorylation; GO:0001952 regulation of cell-matrix adhesion; GO:0032515 negative regulation of phosphoprotein phosphatase activity; GO:0032956 regulation of actin cytoskeleton organization; GO:0031399 regulation of protein modification process; GO:1901700 response to oxygen-containing compound; GO:0051297 centrosome organization; GO:1901889 negative regulation of cell junction assembly; GO:0044267 cellular protein metabolic process; GO:0045604 regulation of epidermal cell differentiation; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:2000147 positive regulation of cell motility; GO:0051239 regulation of multicellular organismal process; GO:1990778 protein localization to cell periphery; GO:0046483 heterocycle metabolic process; GO:0000910 cytokinesis; GO:1902578 single-organism localization; GO:0006139 nucleobase-containing compound metabolic process; GO:0010628 positive regulation of gene expression; GO:2000145 regulation of cell motility; GO:0035308 negative regulation of protein dephosphorylation; GO:1902580 single-organism cellular localization; GO:1903347 negative regulation of bicellular tight junction assembly; GO:0007010 cytoskeleton organization; GO:0034613 cellular protein localization; GO:0090150 establishment of protein localization to membrane; GO:1901550 regulation of endothelial cell development; GO:0045787 positive regulation of cell cycle; GO:1901655 cellular response to ketone; GO:0051495 positive regulation of cytoskeleton organization; GO:0051270 regulation of cellular component movement; GO:0032231 regulation of actin filament bundle assembly; GO:0060284 regulation of cell development; GO:0071407 cellular response to organic cyclic compound; GO:0032970 regulation of actin filament-based process; GO:0030334 regulation of cell migration; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0007017 microtubule-based process; GO:0030155 regulation of cell adhesion; GO:0051492 regulation of stress fiber assembly; GO:0045184 establishment of protein localization; GO:0072659 protein localization to plasma membrane; GO:0051247 positive regulation of protein metabolic process; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0030029 actin filament-based process; GO:0061024 membrane organization; GO:0007249 I-kappaB kinase/NF-kappaB signaling; GO:0043412 macromolecule modification; GO:0051179 localization; GO:0010810 regulation of cell-substrate adhesion; GO:0050793 regulation of developmental process; GO:0045936 negative regulation of phosphate metabolic process; GO:0051093 negative regulation of developmental process; GO:0003012 muscle system process; GO:0010256 endomembrane system organization; GO:0007098 centrosome cycle; GO:1903391 regulation of adherens junction organization; GO:0040017 positive regulation of locomotion; GO:0051129 negative regulation of cellular component organization; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0090109 regulation of cell-substrate junction assembly; GO:0044764 multi-organism cellular process; GO:0010923 negative regulation of phosphatase activity; GO:0031400 negative regulation of protein modification process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0042752 regulation of circadian rhythm; GO:0035303 regulation of dephosphorylation; GO:0007266 Rho protein signal transduction; GO:0039703 RNA replication; GO:0010825 positive regulation of centrosome duplication; GO:0033036 macromolecule localization; GO:0051726 regulation of cell cycle; GO:0070887 cellular response to chemical stimulus; GO:0007167 enzyme linked receptor protein signaling pathway; GO:2000181 negative regulation of blood vessel morphogenesis; GO:0010468 regulation of gene expression; GO:0032878 regulation of establishment or maintenance of cell polarity; GO:0045937 positive regulation of phosphate metabolic process; GO:0051298 centrosome duplication; GO:0030866 cortical actin cytoskeleton organization; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0033574 response to testosterone; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0035509 negative regulation of myosin-light-chain-phosphatase activity; GO:0016070 RNA metabolic process; GO:1902589 single-organism organelle organization; GO:0016525 negative regulation of angiogenesis; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0010638 positive regulation of organelle organization; GO:0045616 regulation of keratinocyte differentiation; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0036211 protein modification process; GO:0007265 Ras protein signal transduction; GO:2000026 regulation of multicellular organismal development; GO:0016043 cellular component organization; GO:0043666 regulation of phosphoprotein phosphatase activity; GO:0006725 cellular aromatic compound metabolic process; GO:0010595 positive regulation of endothelial cell migration; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0071310 cellular response to organic substance; GO:0051893 regulation of focal adhesion assembly; GO:0044087 regulation of cellular component biogenesis; GO:0031324 negative regulation of cellular metabolic process; GO:0030865 cortical cytoskeleton organization; GO:0050896 response to stimulus; GO:0051346 negative regulation of hydrolase activity; GO:0071704 organic substance metabolic process; GO:0033993 response to lipid; GO:0006936 muscle contraction; GO:0048013 ephrin receptor signaling pathway; GO:0006468 protein phosphorylation; GO:0016032 viral process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0070507 regulation of microtubule cytoskeleton organization; GO:0003008 system process; GO:0010921 regulation of phosphatase activity; GO:0035556 intracellular signal transduction; GO:0046607 positive regulation of centrosome cycle; GO:1901342 regulation of vasculature development; GO:0001932 regulation of protein phosphorylation; GO:0006807 nitrogen compound metabolic process; GO:0031401 positive regulation of protein modification process; GO:0044802 single-organism membrane organization; GO:0033043 regulation of organelle organization; GO:0010634 positive regulation of epithelial cell migration; GO:0001934 positive regulation of protein phosphorylation; GO:0045601 regulation of endothelial cell differentiation; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0071394 cellular response to testosterone stimulus; GO:0070727 cellular macromolecule localization; GO:1901701 cellular response to oxygen-containing compound; GO:0048511 rhythmic process; GO:0051246 regulation of protein metabolic process; GO:0031023 microtubule organizing center organization; GO:0022603 regulation of anatomical structure morphogenesis; GO:0010563 negative regulation of phosphorus metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0051128 regulation of cellular component organization; GO:0022402 cell cycle process; GO:0040012 regulation of locomotion; GO:1903140 regulation of establishment of endothelial barrier; GO:0007049 cell cycle; GO:1901654 response to ketone; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0043232 intracellular non-membrane-bounded organelle; GO:0071944 cell periphery; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0005886 plasma membrane; GO:0043228 non-membrane-bounded organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0043226 organelle; GO:0005634 nucleus; GO:0005815 microtubule organizing center; GO:0015630 microtubule cytoskeleton; GO:0005813 centrosome; GO:0005622 intracellular; GO:0044464 cell part; GO:0035770 ribonucleoprotein granule; GO:1990904 ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0030529 intracellular ribonucleoprotein complex; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0005515 protein binding; GO:0004672 protein kinase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016301 kinase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0017016 Ras GTPase binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0051020 GTPase binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0031267 small GTPase binding; GO:0003723 RNA binding; GO:0017048 Rho GTPase binding; GO:0005524 ATP binding; GO:0072518 Rho-dependent protein serine/threonine kinase activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003676 nucleic acid binding; GO:0046872 metal ion binding; GO:0004674 protein serine/threonine kinase activity; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0005198 structural molecule activity; GO:0019899 enzyme binding; GO:0036094 small molecule binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K17388","ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]","hsa04921 Oxytocin signaling pathway - Homo sapiens (human); hsa05132 Salmonella infection - Homo sapiens (human); hsa04530 Tight junction - Homo sapiens (human); hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human); hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human); hsa04270 Vascular smooth muscle contraction - Homo sapiens (human); hsa04024 cAMP signaling pathway - Homo sapiens (human); hsa04670 Leukocyte transendothelial migration - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa05131 Shigellosis - Homo sapiens (human); hsa04062 Chemokine signaling pathway - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa04071 Sphingolipid signaling pathway - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa04611 Platelet activation - Homo sapiens (human); hsa04360 Axon guidance - Homo sapiens (human); hsa04310 Wnt signaling pathway - Homo sapiens (human); ","IPR002219; IPR015008; IPR000719; IPR011993; IPR011009; IPR000961; IPR001849; ","\"Protein kinase C-like, phorbol ester/diacylglycerol-binding domain; Rho binding domain; Protein kinase domain; PH domain-like; Protein kinase-like domain; AGC-kinase, C-terminal; Pleckstrin homology domain; \"\r"]
["O75122","CLIP-associating protein 2 OS=Homo sapiens OX=9606 GN=CLASP2","CLASP2",141.13,6.0771,3.3,5,5,3,1.06,0.987,0.978,0.963,0.924,1.097,0.986,0.799,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0060627 regulation of vesicle-mediated transport; GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0030335 positive regulation of cell migration; GO:0048008 platelet-derived growth factor receptor signaling pathway; GO:0010717 regulation of epithelial to mesenchymal transition; GO:0031109 microtubule polymerization or depolymerization; GO:0031111 negative regulation of microtubule polymerization or depolymerization; GO:0007166 cell surface receptor signaling pathway; GO:0034453 microtubule anchoring; GO:0090002 establishment of protein localization to plasma membrane; GO:1904261 positive regulation of basement membrane assembly involved in embryonic body morphogenesis; GO:0001558 regulation of cell growth; GO:0051240 positive regulation of multicellular organismal process; GO:0065003 macromolecular complex assembly; GO:0032879 regulation of localization; GO:0032535 regulation of cellular component size; GO:0032102 negative regulation of response to external stimulus; GO:0044770 cell cycle phase transition; GO:0010458 exit from mitosis; GO:0051493 regulation of cytoskeleton organization; GO:0008104 protein localization; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0000278 mitotic cell cycle; GO:0007059 chromosome segregation; GO:0010632 regulation of epithelial cell migration; GO:0072657 protein localization to membrane; GO:0045921 positive regulation of exocytosis; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:1903392 negative regulation of adherens junction organization; GO:0007163 establishment or maintenance of cell polarity; GO:0051272 positive regulation of cellular component movement; GO:0007009 plasma membrane organization; GO:1901888 regulation of cell junction assembly; GO:0007026 negative regulation of microtubule depolymerization; GO:2000146 negative regulation of cell motility; GO:0032501 multicellular organismal process; GO:0031114 regulation of microtubule depolymerization; GO:0006810 transport; GO:0032886 regulation of microtubule-based process; GO:0000226 microtubule cytoskeleton organization; GO:0007030 Golgi organization; GO:0090091 positive regulation of extracellular matrix disassembly; GO:0007020 microtubule nucleation; GO:0048583 regulation of response to stimulus; GO:0051301 cell division; GO:0097435 supramolecular fiber organization; GO:0051094 positive regulation of developmental process; GO:0010975 regulation of neuron projection development; GO:1902903 regulation of supramolecular fiber organization; GO:0051047 positive regulation of secretion; GO:0051640 organelle localization; GO:0050794 regulation of cellular process; GO:0001952 regulation of cell-matrix adhesion; GO:0044707 single-multicellular organism process; GO:0007162 negative regulation of cell adhesion; GO:1903690 negative regulation of wound healing, spreading of epidermal cells; GO:0032956 regulation of actin cytoskeleton organization; GO:1901889 negative regulation of cell junction assembly; GO:0017157 regulation of exocytosis; GO:0007051 spindle organization; GO:2000147 positive regulation of cell motility; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0051239 regulation of multicellular organismal process; GO:1990778 protein localization to cell periphery; GO:1904259 regulation of basement membrane assembly involved in embryonic body morphogenesis; GO:0010715 regulation of extracellular matrix disassembly; GO:0010470 regulation of gastrulation; GO:1902578 single-organism localization; GO:2000145 regulation of cell motility; GO:1902580 single-organism cellular localization; GO:0007275 multicellular organism development; GO:0001953 negative regulation of cell-matrix adhesion; GO:0035791 platelet-derived growth factor receptor-beta signaling pathway; GO:0034613 cellular protein localization; GO:0007010 cytoskeleton organization; GO:0090150 establishment of protein localization to membrane; GO:0006461 protein complex assembly; GO:0044772 mitotic cell cycle phase transition; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0032231 regulation of actin filament bundle assembly; GO:0051960 regulation of nervous system development; GO:0060284 regulation of cell development; GO:1901879 regulation of protein depolymerization; GO:0016192 vesicle-mediated transport; GO:0032101 regulation of response to external stimulus; GO:0030334 regulation of cell migration; GO:0032970 regulation of actin filament-based process; GO:0051656 establishment of organelle localization; GO:0007017 microtubule-based process; GO:0030155 regulation of cell adhesion; GO:0050770 regulation of axonogenesis; GO:0051492 regulation of stress fiber assembly; GO:0045184 establishment of protein localization; GO:0072659 protein localization to plasma membrane; GO:0051276 chromosome organization; GO:0061041 regulation of wound healing; GO:0030516 regulation of axon extension; GO:0030336 negative regulation of cell migration; GO:0098813 nuclear chromosome segregation; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0061387 regulation of extent of cell growth; GO:0000280 nuclear division; GO:0007062 sister chromatid cohesion; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:0010810 regulation of cell-substrate adhesion; GO:0051179 localization; GO:1903034 regulation of response to wounding; GO:0050793 regulation of developmental process; GO:1905331 negative regulation of morphogenesis of an epithelium; GO:0051093 negative regulation of developmental process; GO:0010256 endomembrane system organization; GO:1903391 regulation of adherens junction organization; GO:0040017 positive regulation of locomotion; GO:0048869 cellular developmental process; GO:0051129 negative regulation of cellular component organization; GO:0007067 mitotic nuclear division; GO:0090109 regulation of cell-substrate junction assembly; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0051046 regulation of secretion; GO:0031110 regulation of microtubule polymerization or depolymerization; GO:0051234 establishment of localization; GO:0040013 negative regulation of locomotion; GO:0051130 positive regulation of cellular component organization; GO:1905330 regulation of morphogenesis of an epithelium; GO:0000819 sister chromatid segregation; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0032271 regulation of protein polymerization; GO:0033036 macromolecule localization; GO:1903689 regulation of wound healing, spreading of epidermal cells; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0032502 developmental process; GO:0051650 establishment of vesicle localization; GO:0071822 protein complex subunit organization; GO:0051494 negative regulation of cytoskeleton organization; GO:0048522 positive regulation of cellular process; GO:0031113 regulation of microtubule polymerization; GO:0023052 signaling; GO:1903530 regulation of secretion by cell; GO:1901203 positive regulation of extracellular matrix assembly; GO:1903035 negative regulation of response to wounding; GO:0051050 positive regulation of transport; GO:1902589 single-organism organelle organization; GO:0010639 negative regulation of organelle organization; GO:0043254 regulation of protein complex assembly; GO:0050789 regulation of biological process; GO:0045664 regulation of neuron differentiation; GO:1903532 positive regulation of secretion by cell; GO:0051895 negative regulation of focal adhesion assembly; GO:0043242 negative regulation of protein complex disassembly; GO:0051258 protein polymerization; GO:1902904 negative regulation of supramolecular fiber organization; GO:1902850 microtubule cytoskeleton organization involved in mitosis; GO:0043244 regulation of protein complex disassembly; GO:0046785 microtubule polymerization; GO:0070271 protein complex biogenesis; GO:0010812 negative regulation of cell-substrate adhesion; GO:0048856 anatomical structure development; GO:0032232 negative regulation of actin filament bundle assembly; GO:0051271 negative regulation of cellular component movement; GO:2000026 regulation of multicellular organismal development; GO:0040019 positive regulation of embryonic development; GO:0016043 cellular component organization; GO:0040008 regulation of growth; GO:0048285 organelle fission; GO:0051893 regulation of focal adhesion assembly; GO:0031344 regulation of cell projection organization; GO:0044087 regulation of cellular component biogenesis; GO:0006903 vesicle targeting; GO:0048638 regulation of developmental growth; GO:0050896 response to stimulus; GO:1901880 negative regulation of protein depolymerization; GO:0030154 cell differentiation; GO:0008361 regulation of cell size; GO:0051648 vesicle localization; GO:0007052 mitotic spindle organization; GO:0009987 cellular process; GO:0043623 cellular protein complex assembly; GO:0045595 regulation of cell differentiation; GO:1901201 regulation of extracellular matrix assembly; GO:0034622 cellular macromolecular complex assembly; GO:0070507 regulation of microtubule cytoskeleton organization; GO:0051049 regulation of transport; GO:1903053 regulation of extracellular matrix organization; GO:0051497 negative regulation of stress fiber assembly; GO:0044802 single-organism membrane organization; GO:0033043 regulation of organelle organization; GO:0010634 positive regulation of epithelial cell migration; GO:0048585 negative regulation of response to stimulus; GO:0061045 negative regulation of wound healing; GO:0048518 positive regulation of biological process; GO:1903055 positive regulation of extracellular matrix organization; GO:0043933 macromolecular complex subunit organization; GO:0051641 cellular localization; GO:0070727 cellular macromolecule localization; GO:0045995 regulation of embryonic development; GO:0031023 microtubule organizing center organization; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0090066 regulation of anatomical structure size; GO:0022402 cell cycle process; GO:0051128 regulation of cellular component organization; GO:0040012 regulation of locomotion; GO:0022604 regulation of cell morphogenesis; GO:0007049 cell cycle; GO:0044089 positive regulation of cellular component biogenesis; GO:0050767 regulation of neurogenesis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0035371 microtubule plus-end; GO:0032587 ruffle membrane; GO:0045180 basal cortex; GO:0005737 cytoplasm; GO:0099568 cytoplasmic region; GO:0032991 macromolecular complex; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0000793 condensed chromosome; GO:0055028 cortical microtubule; GO:0098590 plasma membrane region; GO:0099738 cell cortex region; GO:0031256 leading edge membrane; GO:0005622 intracellular; GO:0098791 Golgi subcompartment; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0000776 kinetochore; GO:0031252 cell leading edge; GO:0099513 polymeric cytoskeletal fiber; GO:0042995 cell projection; GO:0000779 condensed chromosome, centromeric region; GO:0044430 cytoskeletal part; GO:0030427 site of polarized growth; GO:0033267 axon part; GO:0099081 supramolecular polymer; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0030424 axon; GO:0044295 axonal growth cone; GO:0043234 protein complex; GO:1904511 cytoplasmic microtubule plus-end; GO:0005938 cell cortex; GO:0005874 microtubule; GO:0005881 cytoplasmic microtubule; GO:0071944 cell periphery; GO:0030863 cortical cytoskeleton; GO:0030426 growth cone; GO:0044424 intracellular part; GO:0099512 supramolecular fiber; GO:1990752 microtubule end; GO:0000777 condensed chromosome kinetochore; GO:0044427 chromosomal part; GO:0005856 cytoskeleton; GO:0005815 microtubule organizing center; GO:0015630 microtubule cytoskeleton; GO:0044464 cell part; GO:0044425 membrane part; GO:0005694 chromosome; GO:0030981 cortical microtubule cytoskeleton; GO:0044431 Golgi apparatus part; GO:0005828 kinetochore microtubule; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044463 cell projection part; GO:0005829 cytosol; GO:0005819 spindle; GO:1903754 cortical microtubule plus-end; GO:0005876 spindle microtubule; GO:0043226 organelle; GO:0098687 chromosomal region; GO:0044459 plasma membrane part; GO:0044448 cell cortex part; GO:0005802 trans-Golgi network; GO:0000775 chromosome, centromeric region; GO:0031253 cell projection membrane; GO:0001726 ruffle; GO:0005794 Golgi apparatus; GO:0031984 organelle subcompartment; GO:0044444 cytoplasmic part; GO:0045178 basal part of cell; ","GO:0051015 actin filament binding; GO:1990782 protein tyrosine kinase binding; GO:0002162 dystroglycan binding; GO:0019901 protein kinase binding; GO:0044877 macromolecular complex binding; GO:0015631 tubulin binding; GO:0005515 protein binding; GO:0051010 microtubule plus-end binding; GO:0019900 kinase binding; GO:0097367 carbohydrate derivative binding; GO:0008092 cytoskeletal protein binding; GO:0008017 microtubule binding; GO:0005488 binding; GO:0003779 actin binding; GO:0001948 glycoprotein binding; GO:0019899 enzyme binding; GO:0032403 protein complex binding; ","K16578",null,null,"IPR034085; IPR011989; IPR024395; IPR016024; ","TOG domain; Armadillo-like helical; CLASP N-terminal domain; Armadillo-type fold; \r"]
["O75131","Copine-3 OS=Homo sapiens OX=9606 GN=CPNE3","CPNE3",60.13,80.634,33.3,16,25,15,0.973,1.023,1.004,0.977,1.002,1.019,0.999,0.976,"extracellular\r","GO:0044700 single organism signaling; GO:0030335 positive regulation of cell migration; GO:0046486 glycerolipid metabolic process; GO:0045321 leukocyte activation; GO:0007166 cell surface receptor signaling pathway; GO:0040017 positive regulation of locomotion; GO:0008654 phospholipid biosynthetic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0009058 biosynthetic process; GO:0071363 cellular response to growth factor stimulus; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0008610 lipid biosynthetic process; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0032879 regulation of localization; GO:0006650 glycerophospholipid metabolic process; GO:0038127 ERBB signaling pathway; GO:0070848 response to growth factor; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0010035 response to inorganic substance; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0070887 cellular response to chemical stimulus; GO:0006629 lipid metabolic process; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0048522 positive regulation of cellular process; GO:0051272 positive regulation of cellular component movement; GO:0023052 signaling; GO:0002444 myeloid leukocyte mediated immunity; GO:0010038 response to metal ion; GO:0090407 organophosphate biosynthetic process; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0044710 single-organism metabolic process; GO:0032940 secretion by cell; GO:0046474 glycerophospholipid biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0071241 cellular response to inorganic substance; GO:0006464 cellular protein modification process; GO:0043299 leukocyte degranulation; GO:0036211 protein modification process; GO:0050794 regulation of cellular process; GO:0016310 phosphorylation; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0071310 cellular response to organic substance; GO:0044267 cellular protein metabolic process; GO:2000147 positive regulation of cell motility; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0006468 protein phosphorylation; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:2000145 regulation of cell motility; GO:0051592 response to calcium ion; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0044711 single-organism biosynthetic process; GO:0051270 regulation of cellular component movement; GO:0016192 vesicle-mediated transport; GO:0071277 cellular response to calcium ion; GO:0030334 regulation of cell migration; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0043312 neutrophil degranulation; GO:1901576 organic substance biosynthetic process; GO:0048518 positive regulation of biological process; GO:0002263 cell activation involved in immune response; GO:0044249 cellular biosynthetic process; GO:0045017 glycerolipid biosynthetic process; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0038128 ERBB2 signaling pathway; GO:0006793 phosphorus metabolic process; GO:0019637 organophosphate metabolic process; GO:0001775 cell activation; GO:0006644 phospholipid metabolic process; GO:0043412 macromolecule modification; GO:0071248 cellular response to metal ion; GO:0051179 localization; GO:0040012 regulation of locomotion; GO:0006955 immune response; GO:0065007 biological regulation; GO:0006887 exocytosis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0005765 lysosomal membrane; GO:0005925 focal adhesion; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030055 cell-substrate junction; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0035577 azurophil granule membrane; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0042582 azurophil granule; GO:0098852 lytic vacuole membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0030667 secretory granule membrane; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0003723 RNA binding; GO:0005544 calcium-dependent phospholipid binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:1990782 protein tyrosine kinase binding; GO:0005102 receptor binding; GO:0019901 protein kinase binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0004672 protein kinase activity; GO:0019900 kinase binding; GO:0048306 calcium-dependent protein binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016301 kinase activity; GO:0030971 receptor tyrosine kinase binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0005543 phospholipid binding; GO:0003676 nucleic acid binding; GO:0008289 lipid binding; GO:0004674 protein serine/threonine kinase activity; GO:0043168 anion binding; GO:0016740 transferase activity; GO:0019899 enzyme binding; GO:0005215 transporter activity; GO:0016772 transferase activity, transferring phosphorus-containing groups; ",{"$nulls":3},"IPR010734; IPR000008; IPR002035; ","\"Copine; C2 domain; von Willebrand factor, type A; \"\r"]
["O75146","Huntingtin-interacting protein 1-related protein OS=Homo sapiens OX=9606 GN=HIP1R","HIP1R",119.39,16.662,7.1,8,8,8,0.848,0.969,0.872,1.131,1.061,1.119,1.231,0.00977,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:0060627 regulation of vesicle-mediated transport; GO:0065008 regulation of biological quality; GO:0010941 regulation of cell death; GO:0032270 positive regulation of cellular protein metabolic process; GO:0030832 regulation of actin filament length; GO:0010821 regulation of mitochondrion organization; GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway; GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway; GO:1901028 regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; GO:0065003 macromolecular complex assembly; GO:0032879 regulation of localization; GO:0032535 regulation of cellular component size; GO:0044093 positive regulation of molecular function; GO:0044057 regulation of system process; GO:0090559 regulation of membrane permeability; GO:0051493 regulation of cytoskeleton organization; GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0051099 positive regulation of binding; GO:0031333 negative regulation of protein complex assembly; GO:0052548 regulation of endopeptidase activity; GO:0048259 regulation of receptor-mediated endocytosis; GO:0010950 positive regulation of endopeptidase activity; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0006810 transport; GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0010604 positive regulation of macromolecule metabolic process; GO:0030837 negative regulation of actin filament polymerization; GO:0060548 negative regulation of cell death; GO:0010952 positive regulation of peptidase activity; GO:0043068 positive regulation of programmed cell death; GO:1902903 regulation of supramolecular fiber organization; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:2001056 positive regulation of cysteine-type endopeptidase activity; GO:0007006 mitochondrial membrane organization; GO:0032956 regulation of actin cytoskeleton organization; GO:0043067 regulation of programmed cell death; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0051239 regulation of multicellular organismal process; GO:0051345 positive regulation of hydrolase activity; GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway; GO:1901030 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; GO:0007275 multicellular organism development; GO:0006898 receptor-mediated endocytosis; GO:0009966 regulation of signal transduction; GO:0006461 protein complex assembly; GO:0030100 regulation of endocytosis; GO:0051125 regulation of actin nucleation; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0055123 digestive system development; GO:0032970 regulation of actin filament-based process; GO:0048268 clathrin coat assembly; GO:0030162 regulation of proteolysis; GO:0008064 regulation of actin polymerization or depolymerization; GO:0051247 positive regulation of protein metabolic process; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0061024 membrane organization; GO:0031647 regulation of protein stability; GO:0012501 programmed cell death; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0050821 protein stabilization; GO:1905445 positive regulation of clathrin coat assembly; GO:0030833 regulation of actin filament polymerization; GO:0051129 negative regulation of cellular component organization; GO:0032092 positive regulation of protein binding; GO:0023051 regulation of signaling; GO:0006839 mitochondrial transport; GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation; GO:0044699 single-organism process; GO:0051046 regulation of secretion; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:2001233 regulation of apoptotic signaling pathway; GO:0010646 regulation of cell communication; GO:0009893 positive regulation of metabolic process; GO:0022607 cellular component assembly; GO:0006915 apoptotic process; GO:0007005 mitochondrion organization; GO:0032271 regulation of protein polymerization; GO:0031334 positive regulation of protein complex assembly; GO:2000586 regulation of platelet-derived growth factor receptor-beta signaling pathway; GO:0032502 developmental process; GO:0071822 protein complex subunit organization; GO:2000116 regulation of cysteine-type endopeptidase activity; GO:0051494 negative regulation of cytoskeleton organization; GO:0051098 regulation of binding; GO:0048522 positive regulation of cellular process; GO:0060453 regulation of gastric acid secretion; GO:0010942 positive regulation of cell death; GO:0051050 positive regulation of transport; GO:0010639 negative regulation of organelle organization; GO:1902589 single-organism organelle organization; GO:0043254 regulation of protein complex assembly; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0010638 positive regulation of organelle organization; GO:1902904 negative regulation of supramolecular fiber organization; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:2000369 regulation of clathrin-dependent endocytosis; GO:0052547 regulation of peptidase activity; GO:0070271 protein complex biogenesis; GO:0048856 anatomical structure development; GO:0016043 cellular component organization; GO:0043069 negative regulation of programmed cell death; GO:0060255 regulation of macromolecule metabolic process; GO:0043065 positive regulation of apoptotic process; GO:0044087 regulation of cellular component biogenesis; GO:0044058 regulation of digestive system process; GO:0043393 regulation of protein binding; GO:0072583 clathrin-dependent endocytosis; GO:0045862 positive regulation of proteolysis; GO:0046902 regulation of mitochondrial membrane permeability; GO:0043066 negative regulation of apoptotic process; GO:1901184 regulation of ERBB signaling pathway; GO:0023056 positive regulation of signaling; GO:2001235 positive regulation of apoptotic signaling pathway; GO:0010647 positive regulation of cell communication; GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0009987 cellular process; GO:0043623 cellular protein complex assembly; GO:0034622 cellular macromolecular complex assembly; GO:1901186 positive regulation of ERBB signaling pathway; GO:0051049 regulation of transport; GO:0051126 negative regulation of actin nucleation; GO:0033043 regulation of organelle organization; GO:0044802 single-organism membrane organization; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0010822 positive regulation of mitochondrion organization; GO:0043085 positive regulation of catalytic activity; GO:0043933 macromolecular complex subunit organization; GO:1905443 regulation of clathrin coat assembly; GO:0008219 cell death; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0090066 regulation of anatomical structure size; GO:0051128 regulation of cellular component organization; GO:0009967 positive regulation of signal transduction; GO:0042058 regulation of epidermal growth factor receptor signaling pathway; GO:0032272 negative regulation of protein polymerization; GO:0044089 positive regulation of cellular component biogenesis; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0030425 dendrite; GO:0016020 membrane; GO:0031090 organelle membrane; GO:0032587 ruffle membrane; GO:0005737 cytoplasm; GO:0099568 cytoplasmic region; GO:0044433 cytoplasmic vesicle part; GO:0032838 cell projection cytoplasm; GO:0043025 neuronal cell body; GO:0005623 cell; GO:0044422 organelle part; GO:0043197 dendritic spine; GO:0043228 non-membrane-bounded organelle; GO:0032839 dendrite cytoplasm; GO:0098590 plasma membrane region; GO:0030136 clathrin-coated vesicle; GO:0031256 leading edge membrane; GO:0005622 intracellular; GO:0098589 membrane region; GO:0014069 postsynaptic density; GO:0097060 synaptic membrane; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0045177 apical part of cell; GO:0031252 cell leading edge; GO:0042995 cell projection; GO:0012506 vesicle membrane; GO:0030135 coated vesicle; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0098794 postsynapse; GO:0005905 clathrin-coated pit; GO:0099572 postsynaptic specialization; GO:0016324 apical plasma membrane; GO:0005938 cell cortex; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0032279 asymmetric synapse; GO:0030662 coated vesicle membrane; GO:0005856 cytoskeleton; GO:0044309 neuron spine; GO:0044425 membrane part; GO:0044464 cell part; GO:0098805 whole membrane; GO:0048471 perinuclear region of cytoplasm; GO:0098984 neuron to neuron synapse; GO:0044456 synapse part; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044463 cell projection part; GO:0005829 cytosol; GO:0030665 clathrin-coated vesicle membrane; GO:0045202 synapse; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0044459 plasma membrane part; GO:0001726 ruffle; GO:0031253 cell projection membrane; GO:0044297 cell body; GO:0044444 cytoplasmic part; ","GO:0051015 actin filament binding; GO:0098748 endocytic adaptor activity; GO:1901981 phosphatidylinositol phosphate binding; GO:0030674 protein binding, bridging; GO:0046982 protein heterodimerization activity; GO:0046983 protein dimerization activity; GO:0043167 ion binding; GO:0044877 macromolecular complex binding; GO:0080025 phosphatidylinositol-3,5-bisphosphate binding; GO:0005515 protein binding; GO:0035615 clathrin adaptor activity; GO:0017124 SH3 domain binding; GO:0043325 phosphatidylinositol-3,4-bisphosphate binding; GO:0032051 clathrin light chain binding; GO:1902936 phosphatidylinositol bisphosphate binding; GO:0030276 clathrin binding; GO:0042802 identical protein binding; GO:0008092 cytoskeletal protein binding; GO:0042803 protein homodimerization activity; GO:0005546 phosphatidylinositol-4,5-bisphosphate binding; GO:0005488 binding; GO:0035091 phosphatidylinositol binding; GO:0005543 phospholipid binding; GO:0003779 actin binding; GO:0008289 lipid binding; GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding; GO:0019904 protein domain specific binding; GO:0060090 binding, bridging; GO:0043168 anion binding; GO:0032403 protein complex binding; ","K20040",null,null,"IPR002558; IPR013809; IPR032422; IPR011417; IPR008942; ","\"I/LWEQ domain; ENTH  domain; Huntingtin-interacting protein 1, clathrin-binding domain; AP180 N-terminal homology (ANTH) domain; ENTH/VHS; \"\r"]
["O75153","Clustered mitochondria protein homolog OS=Homo sapiens OX=9606 GN=CLUH","CLUH",146.67,33.146,10.3,14,16,14,0.84,0.945,0.76,1.151,1.226,1.134,1.38,0.00848,"nucleus\r","GO:0051640 organelle localization; GO:0016043 cellular component organization; GO:0051646 mitochondrion localization; GO:0048311 mitochondrion distribution; GO:0006996 organelle organization; GO:0007005 mitochondrion organization; GO:0051179 localization; GO:0009987 cellular process; GO:0071840 cellular component organization or biogenesis; GO:0048312 intracellular distribution of mitochondria; GO:0051641 cellular localization; ","GO:0044424 intracellular part; GO:0005623 cell; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003729 mRNA binding; GO:0003723 RNA binding; GO:0005515 protein binding; GO:0005488 binding; GO:0003676 nucleic acid binding; ","K03255",null,null,"IPR023231; IPR025697; IPR011990; IPR033646; IPR028275; ","\"GSKIP domain; CLU domain; Tetratricopeptide-like helical domain; CLU central domain; Clustered mitochondria protein, N-terminal; \"\r"]
["O75165","DnaJ homolog subfamily C member 13 OS=Homo sapiens OX=9606 GN=DNAJC13","DNAJC13",254.41,54.671,6,12,14,12,0.88,1.069,0.973,0.751,1.199,1.013,1.014,0.994,"plasma membrane\r","GO:0050794 regulation of cellular process; GO:0060627 regulation of vesicle-mediated transport; GO:0016043 cellular component organization; GO:0001649 osteoblast differentiation; GO:0044707 single-multicellular organism process; GO:0010256 endomembrane system organization; GO:0045321 leukocyte activation; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0015031 protein transport; GO:0060341 regulation of cellular localization; GO:0051234 establishment of localization; GO:0030154 cell differentiation; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0032879 regulation of localization; GO:2000641 regulation of early endosome to late endosome transport; GO:0036230 granulocyte activation; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0009987 cellular process; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0032502 developmental process; GO:0002443 leukocyte mediated immunity; GO:0051049 regulation of transport; GO:0001503 ossification; GO:1903649 regulation of cytoplasmic transport; GO:0016192 vesicle-mediated transport; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0016050 vesicle organization; GO:0071702 organic substance transport; GO:0032386 regulation of intracellular transport; GO:0002376 immune system process; GO:0043312 neutrophil degranulation; GO:1902954 regulation of early endosome to recycling endosome transport; GO:0032501 multicellular organismal process; GO:0002263 cell activation involved in immune response; GO:0002444 myeloid leukocyte mediated immunity; GO:0045184 establishment of protein localization; GO:0002366 leukocyte activation involved in immune response; GO:0006810 transport; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:0050789 regulation of biological process; GO:0006996 organelle organization; GO:0032940 secretion by cell; GO:0044767 single-organism developmental process; GO:0001775 cell activation; GO:0043299 leukocyte degranulation; GO:0051179 localization; GO:0006955 immune response; GO:0007032 endosome organization; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:0006887 exocytosis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0070062 extracellular exosome; GO:0005765 lysosomal membrane; GO:0005622 intracellular; GO:0044464 cell part; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0031901 early endosome membrane; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0000323 lytic vacuole; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0010008 endosome membrane; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0035577 azurophil granule membrane; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0012506 vesicle membrane; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0042582 azurophil granule; GO:0098852 lytic vacuole membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0030667 secretory granule membrane; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ","K09533",null,null,"IPR011989; IPR001623; IPR016024; IPR025640; IPR003169; ","Armadillo-like helical; DnaJ domain; Armadillo-type fold; Domain of unknown function DUF4339; GYF domain; \r"]
["O75175","CCR4-NOT transcription complex subunit 3 OS=Homo sapiens OX=9606 GN=CNOT3","CNOT3",81.871,6.3031,2.5,2,2,2,0.931,1.144,0.951,0.987,1.028,0.972,0.987,0.902,"nucleus\r","GO:0044700 single organism signaling; GO:1902807 negative regulation of cell cycle G1/S phase transition; GO:0097659 nucleic acid-templated transcription; GO:0010608 posttranscriptional regulation of gene expression; GO:0043009 chordate embryonic development; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0072431 signal transduction involved in mitotic G1 DNA damage checkpoint; GO:1902403 signal transduction involved in mitotic DNA integrity checkpoint; GO:0008152 metabolic process; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0043170 macromolecule metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0090068 positive regulation of cell cycle process; GO:0009790 embryo development; GO:0051716 cellular response to stimulus; GO:0000278 mitotic cell cycle; GO:0018130 heterocycle biosynthetic process; GO:0044773 mitotic DNA damage checkpoint; GO:0080090 regulation of primary metabolic process; GO:2000134 negative regulation of G1/S transition of mitotic cell cycle; GO:0044763 single-organism cellular process; GO:0034249 negative regulation of cellular amide metabolic process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0010948 negative regulation of cell cycle process; GO:0072413 signal transduction involved in mitotic cell cycle checkpoint; GO:0031047 gene silencing by RNA; GO:0001701 in utero embryonic development; GO:1902400 intracellular signal transduction involved in G1 DNA damage checkpoint; GO:0032269 negative regulation of cellular protein metabolic process; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0044707 single-multicellular organism process; GO:0007346 regulation of mitotic cell cycle; GO:0001829 trophectodermal cell differentiation; GO:0017148 negative regulation of translation; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0001825 blastocyst formation; GO:0051239 regulation of multicellular organismal process; GO:0030330 DNA damage response, signal transduction by p53 class mediator; GO:0044270 cellular nitrogen compound catabolic process; GO:0009653 anatomical structure morphogenesis; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1902402 signal transduction involved in mitotic DNA damage checkpoint; GO:1901987 regulation of cell cycle phase transition; GO:0009889 regulation of biosynthetic process; GO:0044819 mitotic G1/S transition checkpoint; GO:0007093 mitotic cell cycle checkpoint; GO:0044248 cellular catabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0007275 multicellular organism development; GO:0048646 anatomical structure formation involved in morphogenesis; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0045787 positive regulation of cell cycle; GO:0006950 response to stress; GO:0072331 signal transduction by p53 class mediator; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0001824 blastocyst development; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0006974 cellular response to DNA damage stimulus; GO:0034248 regulation of cellular amide metabolic process; GO:0009890 negative regulation of biosynthetic process; GO:0050793 regulation of developmental process; GO:2000045 regulation of G1/S transition of mitotic cell cycle; GO:0048869 cellular developmental process; GO:0044783 G1 DNA damage checkpoint; GO:0044699 single-organism process; GO:2000036 regulation of stem cell population maintenance; GO:0009058 biosynthetic process; GO:2001141 regulation of RNA biosynthetic process; GO:0045930 negative regulation of mitotic cell cycle; GO:0007165 signal transduction; GO:0000077 DNA damage checkpoint; GO:0044774 mitotic DNA integrity checkpoint; GO:0007154 cell communication; GO:1901991 negative regulation of mitotic cell cycle phase transition; GO:1902806 regulation of cell cycle G1/S phase transition; GO:0000075 cell cycle checkpoint; GO:1901361 organic cyclic compound catabolic process; GO:0051726 regulation of cell cycle; GO:0032502 developmental process; GO:0031571 mitotic G1 DNA damage checkpoint; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0031570 DNA integrity checkpoint; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0006401 RNA catabolic process; GO:0016070 RNA metabolic process; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0019222 regulation of metabolic process; GO:0048856 anatomical structure development; GO:0072401 signal transduction involved in DNA integrity checkpoint; GO:0045786 negative regulation of cell cycle; GO:0072395 signal transduction involved in cell cycle checkpoint; GO:0006725 cellular aromatic compound metabolic process; GO:1901988 negative regulation of cell cycle phase transition; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0042770 signal transduction in response to DNA damage; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0071156 regulation of cell cycle arrest; GO:0044265 cellular macromolecule catabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0072422 signal transduction involved in DNA damage checkpoint; GO:0035556 intracellular signal transduction; GO:0010629 negative regulation of gene expression; GO:0009792 embryo development ending in birth or egg hatching; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0016458 gene silencing; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0006417 regulation of translation; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0009057 macromolecule catabolic process; GO:0071158 positive regulation of cell cycle arrest; GO:0051248 negative regulation of protein metabolic process; GO:0010467 gene expression; GO:0022402 cell cycle process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0065007 biological regulation; GO:0046700 heterocycle catabolic process; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0000932 P-body; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0043228 non-membrane-bounded organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:0035770 ribonucleoprotein granule; GO:0030015 CCR4-NOT core complex; GO:0030014 CCR4-NOT complex; GO:1990904 ribonucleoprotein complex; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0030529 intracellular ribonucleoprotein complex; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ","K12580","CNOT3; CCR4-NOT transcription complex subunit 3","hsa03018 RNA degradation - Homo sapiens (human); ","IPR007282; IPR007207; ","\"NOT2/NOT3/NOT5; CCR4-Not complex component, Not N-terminal domain; \"\r"]
["O75208","Ubiquinone biosynthesis protein COQ9, mitochondrial OS=Homo sapiens OX=9606 GN=COQ9","COQ9",35.509,23.756,17.9,5,9,5,0.36,0.358,1.601,1.353,1.193,1.138,1.589,0.283,"mitochondria\r","GO:0051188 cofactor biosynthetic process; GO:0042181 ketone biosynthetic process; GO:1901663 quinone biosynthetic process; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0042180 cellular ketone metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0009108 coenzyme biosynthetic process; GO:0006743 ubiquinone metabolic process; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0055114 oxidation-reduction process; GO:1901661 quinone metabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006119 oxidative phosphorylation; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0006732 coenzyme metabolic process; GO:0006120 mitochondrial electron transport, NADH to ubiquinone; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0051186 cofactor metabolic process; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0022900 electron transport chain; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0016310 phosphorylation; GO:0006725 cellular aromatic compound metabolic process; GO:0042773 ATP synthesis coupled electron transport; GO:0009259 ribonucleotide metabolic process; GO:0022904 respiratory electron transport chain; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009119 ribonucleoside metabolic process; GO:0009987 cellular process; GO:0046034 ATP metabolic process; GO:0044711 single-organism biosynthetic process; GO:0006744 ubiquinone biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0045333 cellular respiration; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0006163 purine nucleotide metabolic process; GO:0046128 purine ribonucleoside metabolic process; GO:0006793 phosphorus metabolic process; GO:0044283 small molecule biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0031090 organelle membrane; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0005740 mitochondrial envelope; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0031975 envelope; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0008289 lipid binding; GO:0005515 protein binding; GO:0042802 identical protein binding; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0046983 protein dimerization activity; ","K18587",null,null,"IPR013718; ","COQ9; \r"]
["O75223","Gamma-glutamylcyclotransferase OS=Homo sapiens OX=9606 GN=GGCT","GGCT",21.007,30.194,34,6,10,6,0.909,0.899,0.899,1.102,1.08,1.133,1.225,1.44E-4,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0016043 cellular component organization; GO:0097190 apoptotic signaling pathway; GO:0006518 peptide metabolic process; GO:0044699 single-organism process; GO:0042398 cellular modified amino acid biosynthetic process; GO:0009058 biosynthetic process; GO:0050896 response to stimulus; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:0044272 sulfur compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0007154 cell communication; GO:0006575 cellular modified amino acid metabolic process; GO:0006915 apoptotic process; GO:0007005 mitochondrion organization; GO:0006749 glutathione metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009987 cellular process; GO:0006790 sulfur compound metabolic process; GO:0051716 cellular response to stimulus; GO:0008637 apoptotic mitochondrial changes; GO:0043043 peptide biosynthetic process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0023052 signaling; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0001836 release of cytochrome c from mitochondria; GO:0050789 regulation of biological process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0008219 cell death; GO:0006996 organelle organization; GO:0012501 programmed cell death; GO:0043604 amide biosynthetic process; GO:0006750 glutathione biosynthetic process; GO:0019184 nonribosomal peptide biosynthetic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; GO:1901564 organonitrogen compound metabolic process; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016746 transferase activity, transferring acyl groups; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0046983 protein dimerization activity; GO:0003839 gamma-glutamylcyclotransferase activity; GO:0005515 protein binding; GO:0016740 transferase activity; GO:0016755 transferase activity, transferring amino-acyl groups; ","K00682","GGCT; gamma-glutamylcyclotransferase [EC:4.3.2.9]","hsa00480 Glutathione metabolism - Homo sapiens (human); ","IPR013024; ","Gamma-glutamyl cyclotransferase-like; \r"]
["O75306","NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2","NDUFS2",52.545,40.258,26.1,11,14,11,1.035,1.071,1.041,0.86,1.034,1.022,0.927,0.259,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0006753 nucleoside phosphate metabolic process; GO:0007005 mitochondrion organization; GO:0006979 response to oxidative stress; GO:0019693 ribose phosphate metabolic process; GO:0071822 protein complex subunit organization; GO:0010257 NADH dehydrogenase complex assembly; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006119 oxidative phosphorylation; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0006120 mitochondrial electron transport, NADH to ubiquinone; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0097031 mitochondrial respiratory chain complex I biogenesis; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0022900 electron transport chain; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0070271 protein complex biogenesis; GO:0033108 mitochondrial respiratory chain complex assembly; GO:0016310 phosphorylation; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0042773 ATP synthesis coupled electron transport; GO:0009259 ribonucleotide metabolic process; GO:0022904 respiratory electron transport chain; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0032981 mitochondrial respiratory chain complex I assembly; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009119 ribonucleoside metabolic process; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0043623 cellular protein complex assembly; GO:0046034 ATP metabolic process; GO:0034622 cellular macromolecular complex assembly; GO:0006950 response to stress; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0045333 cellular respiration; GO:0006163 purine nucleotide metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0046128 purine ribonucleoside metabolic process; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:0071840 cellular component organization or biogenesis; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0045271 respiratory chain complex I; GO:0032991 macromolecular complex; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0005747 mitochondrial respiratory chain complex I; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0098803 respiratory chain complex; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005759 mitochondrial matrix; GO:0044429 mitochondrial part; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0031981 nuclear lumen; GO:0005739 mitochondrion; GO:0005746 mitochondrial respiratory chain; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0030964 NADH dehydrogenase complex; GO:0031975 envelope; GO:1990204 oxidoreductase complex; GO:0043234 protein complex; GO:0031966 mitochondrial membrane; GO:0070469 respiratory chain; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:1901265 nucleoside phosphate binding; GO:0031625 ubiquitin protein ligase binding; GO:0043167 ion binding; GO:0050136 NADH dehydrogenase (quinone) activity; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0051539 4 iron, 4 sulfur cluster binding; GO:0048037 cofactor binding; GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; GO:0008137 NADH dehydrogenase (ubiquinone) activity; GO:0016491 oxidoreductase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0009055 electron carrier activity; GO:0003954 NADH dehydrogenase activity; GO:0051287 NAD binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0051536 iron-sulfur cluster binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0048038 quinone binding; GO:0019899 enzyme binding; GO:0036094 small molecule binding; GO:0050662 coenzyme binding; GO:0051540 metal cluster binding; ","K03935","NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:1.6.5.3 1.6.99.3]","hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); ","IPR029014; IPR001135; ","\"NiFe hydrogenase-like; NADH-quinone oxidoreductase, subunit D; \"\r"]
["O75312","Zinc finger protein ZPR1 OS=Homo sapiens OX=9606 GN=ZPR1","ZPR1",50.925,8.3803,10,4,4,4,0.854,0.953,0.876,1.131,1.227,0.957,1.236,0.0612,"cytoplasm\r","GO:0044700 single organism signaling; GO:0071931 positive regulation of transcription involved in G1/S transition of mitotic cell cycle; GO:0010941 regulation of cell death; GO:0042023 DNA endoreduplication; GO:1903533 regulation of protein targeting; GO:0043009 chordate embryonic development; GO:0043523 regulation of neuron apoptotic process; GO:0009891 positive regulation of biosynthetic process; GO:0044237 cellular metabolic process; GO:0045927 positive regulation of growth; GO:0008152 metabolic process; GO:0032879 regulation of localization; GO:0009719 response to endogenous stimulus; GO:0070848 response to growth factor; GO:0044770 cell cycle phase transition; GO:0043170 macromolecule metabolic process; GO:0009790 embryo development; GO:0007399 nervous system development; GO:0006396 RNA processing; GO:0051716 cellular response to stimulus; GO:0000278 mitotic cell cycle; GO:0030575 nuclear body organization; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0001834 trophectodermal cell proliferation; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044763 single-organism cellular process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0000226 microtubule cytoskeleton organization; GO:0019439 aromatic compound catabolic process; GO:1901575 organic substance catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0001701 in utero embryonic development; GO:0071364 cellular response to epidermal growth factor stimulus; GO:0007417 central nervous system development; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051223 regulation of protein transport; GO:0060548 negative regulation of cell death; GO:0016071 mRNA metabolic process; GO:0001832 blastocyst growth; GO:0042307 positive regulation of protein import into nucleus; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0033120 positive regulation of RNA splicing; GO:0044707 single-multicellular organism process; GO:0006260 DNA replication; GO:0006259 DNA metabolic process; GO:0043067 regulation of programmed cell death; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:1903047 mitotic cell cycle process; GO:0051239 regulation of multicellular organismal process; GO:0060341 regulation of cellular localization; GO:0044270 cellular nitrogen compound catabolic process; GO:2000671 regulation of motor neuron apoptotic process; GO:0043524 negative regulation of neuron apoptotic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1990261 pre-mRNA catabolic process; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0044248 cellular catabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0032880 regulation of protein localization; GO:0007275 multicellular organism development; GO:0034655 nucleobase-containing compound catabolic process; GO:0007010 cytoskeleton organization; GO:0008380 RNA splicing; GO:0044772 mitotic cell cycle phase transition; GO:1901215 negative regulation of neuron death; GO:0051254 positive regulation of RNA metabolic process; GO:0048731 system development; GO:0051960 regulation of nervous system development; GO:0001824 blastocyst development; GO:0008283 cell proliferation; GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0007017 microtubule-based process; GO:1901576 organic substance biosynthetic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0043484 regulation of RNA splicing; GO:1900182 positive regulation of protein localization to nucleus; GO:0030182 neuron differentiation; GO:0046822 regulation of nucleocytoplasmic transport; GO:1904951 positive regulation of establishment of protein localization; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:1902742 apoptotic process involved in development; GO:0012501 programmed cell death; GO:0048589 developmental growth; GO:0031328 positive regulation of cellular biosynthetic process; GO:0040007 growth; GO:0050793 regulation of developmental process; GO:1903827 regulation of cellular protein localization; GO:1904591 positive regulation of protein import; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0071363 cellular response to growth factor stimulus; GO:2001141 regulation of RNA biosynthetic process; GO:0042306 regulation of protein import into nucleus; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0006915 apoptotic process; GO:0046824 positive regulation of nucleocytoplasmic transport; GO:1901361 organic cyclic compound catabolic process; GO:0001833 inner cell mass cell proliferation; GO:0006261 DNA-dependent DNA replication; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0021510 spinal cord development; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0032386 regulation of intracellular transport; GO:0023052 signaling; GO:0051050 positive regulation of transport; GO:0016070 RNA metabolic process; GO:0006401 RNA catabolic process; GO:0006397 mRNA processing; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0030030 cell projection organization; GO:0030576 Cajal body organization; GO:2000672 negative regulation of motor neuron apoptotic process; GO:1900180 regulation of protein localization to nucleus; GO:0019222 regulation of metabolic process; GO:0048856 anatomical structure development; GO:0051222 positive regulation of protein transport; GO:2000026 regulation of multicellular organismal development; GO:0006997 nucleus organization; GO:0016043 cellular component organization; GO:0043069 negative regulation of programmed cell death; GO:0031641 regulation of myelination; GO:0040008 regulation of growth; GO:0090316 positive regulation of intracellular protein transport; GO:0006725 cellular aromatic compound metabolic process; GO:1903829 positive regulation of cellular protein localization; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:1904589 regulation of protein import; GO:0050896 response to stimulus; GO:0070201 regulation of establishment of protein localization; GO:0048468 cell development; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0043066 negative regulation of apoptotic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0000082 G1/S transition of mitotic cell cycle; GO:0009059 macromolecule biosynthetic process; GO:0033157 regulation of intracellular protein transport; GO:0009987 cellular process; GO:1901214 regulation of neuron death; GO:0044786 cell cycle DNA replication; GO:0044265 cellular macromolecule catabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0070849 response to epidermal growth factor; GO:0044843 cell cycle G1/S phase transition; GO:0051049 regulation of transport; GO:0032388 positive regulation of intracellular transport; GO:0009792 embryo development ending in birth or egg hatching; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0031175 neuron projection development; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0061564 axon development; GO:0034645 cellular macromolecule biosynthetic process; GO:0008219 cell death; GO:0071495 cellular response to endogenous stimulus; GO:0044767 single-organism developmental process; GO:0009057 macromolecule catabolic process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0010467 gene expression; GO:0022402 cell cycle process; GO:0009056 catabolic process; GO:0042981 regulation of apoptotic process; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:0046700 heterocycle catabolic process; ","GO:0005737 cytoplasm; GO:0043025 neuronal cell body; GO:0032991 macromolecular complex; GO:0030426 growth cone; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0015030 Cajal body; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0048471 perinuclear region of cytoplasm; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0032797 SMN complex; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0030427 site of polarized growth; GO:0044463 cell projection part; GO:0030424 axon; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0036477 somatodendritic compartment; GO:0005634 nucleus; GO:0043204 perikaryon; GO:0044297 cell body; GO:0097504 Gemini of coiled bodies; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0030971 receptor tyrosine kinase binding; GO:1990782 protein tyrosine kinase binding; GO:0046914 transition metal ion binding; GO:0005102 receptor binding; GO:0031369 translation initiation factor binding; GO:0005488 binding; GO:0019901 protein kinase binding; GO:0043167 ion binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0019900 kinase binding; GO:0008270 zinc ion binding; GO:0019899 enzyme binding; ","K06874",null,null,"IPR004457; ","\"Zinc finger, ZPR1-type; \"\r"]
["O75323","Protein NipSnap homolog 2 OS=Homo sapiens OX=9606 GN=NIPSNAP2","NIPSNAP2",33.742,28.541,14.3,5,7,5,1.246,1.062,1.164,0.925,0.858,0.776,0.737,0.0113,"mitochondria\r","GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0009163 nucleoside biosynthetic process; GO:0046129 purine ribonucleoside biosynthetic process; GO:0009156 ribonucleoside monophosphate biosynthetic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0046390 ribose phosphate biosynthetic process; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:1901137 carbohydrate derivative biosynthetic process; GO:0006753 nucleoside phosphate metabolic process; GO:0019693 ribose phosphate metabolic process; GO:2000983 regulation of ATP citrate synthase activity; GO:0009145 purine nucleoside triphosphate biosynthetic process; GO:2000984 negative regulation of ATP citrate synthase activity; GO:0018130 heterocycle biosynthetic process; GO:0009206 purine ribonucleoside triphosphate biosynthetic process; GO:0044281 small molecule metabolic process; GO:0006119 oxidative phosphorylation; GO:0006754 ATP biosynthetic process; GO:0044763 single-organism cellular process; GO:0072521 purine-containing compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0051348 negative regulation of transferase activity; GO:0043086 negative regulation of catalytic activity; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0009168 purine ribonucleoside monophosphate biosynthetic process; GO:0042451 purine nucleoside biosynthetic process; GO:0090407 organophosphate biosynthetic process; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0072522 purine-containing compound biosynthetic process; GO:0050790 regulation of catalytic activity; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0006164 purine nucleotide biosynthetic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0009201 ribonucleoside triphosphate biosynthetic process; GO:0016310 phosphorylation; GO:0009165 nucleotide biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0009259 ribonucleotide metabolic process; GO:0009142 nucleoside triphosphate biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0051338 regulation of transferase activity; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0009119 ribonucleoside metabolic process; GO:0009987 cellular process; GO:0046034 ATP metabolic process; GO:0009124 nucleoside monophosphate biosynthetic process; GO:0044711 single-organism biosynthetic process; GO:0009127 purine nucleoside monophosphate biosynthetic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0042455 ribonucleoside biosynthetic process; GO:1901576 organic substance biosynthetic process; GO:0006163 purine nucleotide metabolic process; GO:0044249 cellular biosynthetic process; GO:0046128 purine ribonucleoside metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0009152 purine ribonucleotide biosynthetic process; GO:0006793 phosphorus metabolic process; GO:1901659 glycosyl compound biosynthetic process; GO:0009260 ribonucleotide biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0031226 intrinsic component of plasma membrane; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR012577; IPR011008; ","NIPSNAP; Dimeric alpha-beta barrel; \r"]
["O75340","Programmed cell death protein 6 OS=Homo sapiens OX=9606 GN=PDCD6","PDCD6",21.868,67.153,35.6,5,7,5,1.014,0.998,1.025,0.875,1.041,0.956,0.946,0.369,"cyto_nucl\r","GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0030335 positive regulation of cell migration; GO:0032270 positive regulation of cellular protein metabolic process; GO:0051896 regulation of protein kinase B signaling; GO:0007166 cell surface receptor signaling pathway; GO:0015031 protein transport; GO:0010594 regulation of endothelial cell migration; GO:0008152 metabolic process; GO:0001525 angiogenesis; GO:0051240 positive regulation of multicellular organismal process; GO:0009408 response to heat; GO:0050678 regulation of epithelial cell proliferation; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:1904018 positive regulation of vasculature development; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0008104 protein localization; GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0052548 regulation of endopeptidase activity; GO:0051716 cellular response to stimulus; GO:0010950 positive regulation of endopeptidase activity; GO:0010632 regulation of epithelial cell migration; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0090287 regulation of cellular response to growth factor stimulus; GO:0051272 positive regulation of cellular component movement; GO:0031323 regulation of cellular metabolic process; GO:0001938 positive regulation of endothelial cell proliferation; GO:0032501 multicellular organismal process; GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0006810 transport; GO:0051336 regulation of hydrolase activity; GO:1902532 negative regulation of intracellular signal transduction; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0010604 positive regulation of macromolecule metabolic process; GO:0045765 regulation of angiogenesis; GO:0048010 vascular endothelial growth factor receptor signaling pathway; GO:0051094 positive regulation of developmental process; GO:0010952 positive regulation of peptidase activity; GO:0043068 positive regulation of programmed cell death; GO:0050794 regulation of cellular process; GO:0072359 circulatory system development; GO:0033554 cellular response to stress; GO:0046907 intracellular transport; GO:0044707 single-multicellular organism process; GO:0097190 apoptotic signaling pathway; GO:0042127 regulation of cell proliferation; GO:2001056 positive regulation of cysteine-type endopeptidase activity; GO:0009628 response to abiotic stimulus; GO:0043067 regulation of programmed cell death; GO:2000147 positive regulation of cell motility; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0051239 regulation of multicellular organismal process; GO:0051898 negative regulation of protein kinase B signaling; GO:0009653 anatomical structure morphogenesis; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0051345 positive regulation of hydrolase activity; GO:2000145 regulation of cell motility; GO:0001936 regulation of endothelial cell proliferation; GO:0007275 multicellular organism development; GO:0034613 cellular protein localization; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0009966 regulation of signal transduction; GO:1902531 regulation of intracellular signal transduction; GO:0006950 response to stress; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway; GO:0071702 organic substance transport; GO:0072358 cardiovascular system development; GO:0030334 regulation of cell migration; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0045184 establishment of protein localization; GO:0051247 positive regulation of protein metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0012501 programmed cell death; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0008284 positive regulation of cell proliferation; GO:0009968 negative regulation of signal transduction; GO:0001568 blood vessel development; GO:0040017 positive regulation of locomotion; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0006915 apoptotic process; GO:0048514 blood vessel morphogenesis; GO:0010035 response to inorganic substance; GO:0033036 macromolecule localization; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0032007 negative regulation of TOR signaling; GO:0032502 developmental process; GO:2000116 regulation of cysteine-type endopeptidase activity; GO:0048522 positive regulation of cellular process; GO:0001944 vasculature development; GO:0023052 signaling; GO:0010038 response to metal ion; GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway; GO:0010942 positive regulation of cell death; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0034605 cellular response to heat; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0052547 regulation of peptidase activity; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0010595 positive regulation of endothelial cell migration; GO:0060255 regulation of macromolecule metabolic process; GO:0043065 positive regulation of apoptotic process; GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway; GO:0050896 response to stimulus; GO:0045766 positive regulation of angiogenesis; GO:0071704 organic substance metabolic process; GO:0032006 regulation of TOR signaling; GO:0045862 positive regulation of proteolysis; GO:0009266 response to temperature stimulus; GO:0090288 negative regulation of cellular response to growth factor stimulus; GO:0006886 intracellular protein transport; GO:0051592 response to calcium ion; GO:0006508 proteolysis; GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0009987 cellular process; GO:1901342 regulation of vasculature development; GO:0010634 positive regulation of epithelial cell migration; GO:0048585 negative regulation of response to stimulus; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0043085 positive regulation of catalytic activity; GO:0070727 cellular macromolecule localization; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0040012 regulation of locomotion; GO:0042981 regulation of apoptotic process; GO:0050679 positive regulation of epithelial cell proliferation; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0031965 nuclear membrane; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0005635 nuclear envelope; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0070971 endoplasmic reticulum exit site; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044432 endoplasmic reticulum part; GO:0031975 envelope; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0004198 calcium-dependent cysteine-type endopeptidase activity; GO:0008233 peptidase activity; GO:0043167 ion binding; GO:0046983 protein dimerization activity; GO:0008234 cysteine-type peptidase activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0048306 calcium-dependent protein binding; GO:0004175 endopeptidase activity; GO:0043495 protein anchor; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0042803 protein homodimerization activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0060090 binding, bridging; GO:0005509 calcium ion binding; GO:0004197 cysteine-type endopeptidase activity; ",{"$nulls":3},"IPR011992; IPR002048; ","EF-hand domain pair; EF-hand domain; \r"]
["O75342","Arachidonate 12-lipoxygenase, 12R-type OS=Homo sapiens OX=9606 GN=ALOX12B","ALOX12B",80.355,13.468,5.7,3,3,3,0.897,0.631,0.663,1.287,1.255,1.243,1.728,0.0369,"cytoplasm\r","GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0006672 ceramide metabolic process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0042157 lipoprotein metabolic process; GO:0008610 lipid biosynthetic process; GO:0008152 metabolic process; GO:0030148 sphingolipid biosynthetic process; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0032787 monocarboxylic acid metabolic process; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006690 icosanoid metabolic process; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0043588 skin development; GO:0070257 positive regulation of mucus secretion; GO:0080090 regulation of primary metabolic process; GO:0043651 linoleic acid metabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0048513 animal organ development; GO:0030104 water homeostasis; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006497 protein lipidation; GO:0006464 cellular protein modification process; GO:0043436 oxoacid metabolic process; GO:0051047 positive regulation of secretion; GO:0050794 regulation of cellular process; GO:0033559 unsaturated fatty acid metabolic process; GO:0044707 single-multicellular organism process; GO:0019369 arachidonic acid metabolic process; GO:0042759 long-chain fatty acid biosynthetic process; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0051239 regulation of multicellular organismal process; GO:0010628 positive regulation of gene expression; GO:0061436 establishment of skin barrier; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:0048878 chemical homeostasis; GO:1902531 regulation of intracellular signal transduction; GO:0044711 single-organism biosynthetic process; GO:0048731 system development; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0051247 positive regulation of protein metabolic process; GO:0050891 multicellular organismal water homeostasis; GO:0001676 long-chain fatty acid metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0044283 small molecule biosynthetic process; GO:0070255 regulation of mucus secretion; GO:0048584 positive regulation of response to stimulus; GO:0043412 macromolecule modification; GO:0072330 monocarboxylic acid biosynthetic process; GO:0051122 hepoxilin biosynthetic process; GO:0046513 ceramide biosynthetic process; GO:1901564 organonitrogen compound metabolic process; GO:0016053 organic acid biosynthetic process; GO:0006643 membrane lipid metabolic process; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0051046 regulation of secretion; GO:1901568 fatty acid derivative metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0048871 multicellular organismal homeostasis; GO:0010646 regulation of cell communication; GO:0009893 positive regulation of metabolic process; GO:0006665 sphingolipid metabolic process; GO:0019372 lipoxygenase pathway; GO:0042158 lipoprotein biosynthetic process; GO:0006629 lipid metabolic process; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0045937 positive regulation of phosphate metabolic process; GO:0055114 oxidation-reduction process; GO:0048522 positive regulation of cellular process; GO:0006636 unsaturated fatty acid biosynthetic process; GO:0043603 cellular amide metabolic process; GO:0006633 fatty acid biosynthetic process; GO:0051050 positive regulation of transport; GO:0046394 carboxylic acid biosynthetic process; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0006082 organic acid metabolic process; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0060255 regulation of macromolecule metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0043408 regulation of MAPK cascade; GO:0023056 positive regulation of signaling; GO:0034641 cellular nitrogen compound metabolic process; GO:0010647 positive regulation of cell communication; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0046467 membrane lipid biosynthetic process; GO:0050878 regulation of body fluid levels; GO:0051049 regulation of transport; GO:0001932 regulation of protein phosphorylation; GO:0006807 nitrogen compound metabolic process; GO:0031401 positive regulation of protein modification process; GO:0006631 fatty acid metabolic process; GO:0001934 positive regulation of protein phosphorylation; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0051121 hepoxilin metabolic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0033561 regulation of water loss via skin; GO:0009967 positive regulation of signal transduction; GO:0043604 amide biosynthetic process; GO:0043410 positive regulation of MAPK cascade; GO:0065007 biological regulation; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0044444 cytoplasmic part; ","GO:0004052 arachidonate 12-lipoxygenase activity; GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; GO:1990136 linoleate 9S-lipoxygenase activity; GO:0005506 iron ion binding; GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0051213 dioxygenase activity; GO:0043167 ion binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0016491 oxidoreductase activity; ","K08021","ALOX12B; arachidonate 12-lipoxygenase (R-type) [EC:1.13.11.-]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa04726 Serotonergic synapse - Homo sapiens (human); hsa00590 Arachidonic acid metabolism - Homo sapiens (human); ","IPR001024; IPR013819; ","\"PLAT/LH2 domain; Lipoxygenase, C-terminal; \"\r"]
["O75347","Tubulin-specific chaperone A OS=Homo sapiens OX=9606 GN=TBCA","TBCA",12.855,32.821,48.1,6,8,6,1.029,0.94,0.963,1.021,0.985,1.006,1.027,0.396,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:0016043 cellular component organization; GO:0034622 cellular macromolecular complex assembly; GO:0071822 protein complex subunit organization; GO:0007021 tubulin complex assembly; GO:0043933 macromolecular complex subunit organization; GO:0006457 protein folding; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0070271 protein complex biogenesis; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0007023 post-chaperonin tubulin folding pathway; GO:0043623 cellular protein complex assembly; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0044421 extracellular region part; GO:0005874 microtubule; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0031981 nuclear lumen; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0005730 nucleolus; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0099081 supramolecular polymer; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005856 cytoskeleton; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0008092 cytoskeletal protein binding; GO:0051087 chaperone binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0015631 tubulin binding; GO:0048487 beta-tubulin binding; GO:0005515 protein binding; ","K17292"]
["O75348","V-type proton ATPase subunit G 1 OS=Homo sapiens OX=9606 GN=ATP6V1G1","ATP6V1G1",13.757,25.863,21.2,3,5,3,0.901,0.867,0.866,1.015,1.131,1.12,1.24,0.0044,"nucleus\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0008286 insulin receptor signaling pathway; GO:0007166 cell surface receptor signaling pathway; GO:0030641 regulation of cellular pH; GO:0030004 cellular monovalent inorganic cation homeostasis; GO:0044699 single-organism process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0000041 transition metal ion transport; GO:0007165 signal transduction; GO:1901653 cellular response to peptide; GO:0007154 cell communication; GO:0009719 response to endogenous stimulus; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:1901652 response to peptide; GO:0070887 cellular response to chemical stimulus; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0044765 single-organism transport; GO:0051716 cellular response to stimulus; GO:0098655 cation transmembrane transport; GO:0050801 ion homeostasis; GO:0015682 ferric iron transport; GO:0090383 phagosome acidification; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0098771 inorganic ion homeostasis; GO:0044763 single-organism cellular process; GO:0019725 cellular homeostasis; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0031323 regulation of cellular metabolic process; GO:0033572 transferrin transport; GO:0023052 signaling; GO:0010506 regulation of autophagy; GO:0016241 regulation of macroautophagy; GO:0006810 transport; GO:0071417 cellular response to organonitrogen compound; GO:0010243 response to organonitrogen compound; GO:0050789 regulation of biological process; GO:0032868 response to insulin; GO:0042221 response to chemical; GO:0043434 response to peptide hormone; GO:1901699 cellular response to nitrogen compound; GO:0032870 cellular response to hormone stimulus; GO:1901698 response to nitrogen compound; GO:0032869 cellular response to insulin stimulus; GO:0019222 regulation of metabolic process; GO:0098662 inorganic cation transmembrane transport; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0034220 ion transmembrane transport; GO:0045851 pH reduction; GO:0006885 regulation of pH; GO:0030001 metal ion transport; GO:0071310 cellular response to organic substance; GO:0030003 cellular cation homeostasis; GO:1901700 response to oxygen-containing compound; GO:0006826 iron ion transport; GO:0050896 response to stimulus; GO:0055082 cellular chemical homeostasis; GO:0042592 homeostatic process; GO:1902578 single-organism localization; GO:0006812 cation transport; GO:0055080 cation homeostasis; GO:0071375 cellular response to peptide hormone stimulus; GO:1902600 hydrogen ion transmembrane transport; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0090382 phagosome maturation; GO:0055067 monovalent inorganic cation homeostasis; GO:0098660 inorganic ion transmembrane transport; GO:0071702 organic substance transport; GO:0010033 response to organic substance; GO:0006818 hydrogen transport; GO:0015992 proton transport; GO:0045184 establishment of protein localization; GO:0072512 trivalent inorganic cation transport; GO:0055085 transmembrane transport; GO:1901701 cellular response to oxygen-containing compound; GO:0051453 regulation of intracellular pH; GO:0006873 cellular ion homeostasis; GO:0071495 cellular response to endogenous stimulus; GO:0006811 ion transport; GO:0006996 organelle organization; GO:0051452 intracellular pH reduction; GO:0009725 response to hormone; GO:0051179 localization; GO:0015672 monovalent inorganic cation transport; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0033176 proton-transporting V-type ATPase complex; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0005765 lysosomal membrane; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005764 lysosome; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0016471 vacuolar proton-transporting V-type ATPase complex; GO:0005886 plasma membrane; GO:0098852 lytic vacuole membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0016469 proton-transporting two-sector ATPase complex; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0042625 ATPase coupled ion transmembrane transporter activity; GO:0015399 primary active transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0015077 monovalent inorganic cation transmembrane transporter activity; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0015078 hydrogen ion transmembrane transporter activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0016887 ATPase activity; GO:0019829 cation-transporting ATPase activity; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0043492 ATPase activity, coupled to movement of substances; GO:0005488 binding; GO:0036442 hydrogen-exporting ATPase activity; GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; GO:0022890 inorganic cation transmembrane transporter activity; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism; GO:0005215 transporter activity; GO:0022804 active transmembrane transporter activity; GO:0015075 ion transmembrane transporter activity; GO:0051117 ATPase binding; GO:0022853 active ion transmembrane transporter activity; GO:0017111 nucleoside-triphosphatase activity; GO:0015662 ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism; GO:0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity; GO:0042626 ATPase activity, coupled to transmembrane movement of substances; GO:0042623 ATPase activity, coupled; GO:0008324 cation transmembrane transporter activity; GO:0019899 enzyme binding; GO:0022857 transmembrane transporter activity; ","K02152","ATPeV1G; V-type H+-transporting ATPase subunit G","hsa05120 Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human); hsa04966 Collecting duct acid secretion - Homo sapiens (human); hsa05323 Rheumatoid arthritis - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa04150 mTOR signaling pathway - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05110 Vibrio cholerae infection - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); hsa04721 Synaptic vesicle cycle - Homo sapiens (human); "]
["O75351","Vacuolar protein sorting-associated protein 4B OS=Homo sapiens OX=9606 GN=VPS4B","VPS4B",49.301,33.356,25.7,10,16,6,0.889,1.112,0.858,0.97,1.089,1.062,1.092,0.351,"cytoplasm\r","GO:0060627 regulation of vesicle-mediated transport; GO:0044085 cellular component biogenesis; GO:0010941 regulation of cell death; GO:0052192 movement in environment of other organism involved in symbiotic interaction; GO:0006914 autophagy; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0008152 metabolic process; GO:0032879 regulation of localization; GO:0010824 regulation of centrosome duplication; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0036258 multivesicular body assembly; GO:0051493 regulation of cytoskeleton organization; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0090068 positive regulation of cell cycle process; GO:0008104 protein localization; GO:0044419 interspecies interaction between organisms; GO:0044765 single-organism transport; GO:1903543 positive regulation of exosomal secretion; GO:0051051 negative regulation of transport; GO:0000278 mitotic cell cycle; GO:0007059 chromosome segregation; GO:0006869 lipid transport; GO:1901673 regulation of mitotic spindle assembly; GO:0045921 positive regulation of exocytosis; GO:0007088 regulation of mitotic nuclear division; GO:0039702 viral budding via host ESCRT complex; GO:1903531 negative regulation of secretion by cell; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:1902751 positive regulation of cell cycle G2/M phase transition; GO:0008333 endosome to lysosome transport; GO:0051704 multi-organism process; GO:0032886 regulation of microtubule-based process; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0045931 positive regulation of mitotic cell cycle; GO:0030163 protein catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0051301 cell division; GO:0060548 negative regulation of cell death; GO:0051047 positive regulation of secretion; GO:0046605 regulation of centrosome cycle; GO:0050794 regulation of cellular process; GO:0051640 organelle localization; GO:0046907 intracellular transport; GO:0045920 negative regulation of exocytosis; GO:0007346 regulation of mitotic cell cycle; GO:0030001 metal ion transport; GO:0032509 endosome transport via multivesicular body sorting pathway; GO:0044267 cellular protein metabolic process; GO:0017157 regulation of exocytosis; GO:0007080 mitotic metaphase plate congression; GO:0000920 cell separation after cytokinesis; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:1903541 regulation of exosomal secretion; GO:1903047 mitotic cell cycle process; GO:1901989 positive regulation of cell cycle phase transition; GO:0052126 movement in host environment; GO:1903724 positive regulation of centriole elongation; GO:1902578 single-organism localization; GO:1901987 regulation of cell cycle phase transition; GO:0043624 cellular protein complex disassembly; GO:0044248 cellular catabolic process; GO:0010389 regulation of G2/M transition of mitotic cell cycle; GO:0045787 positive regulation of cell cycle; GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway; GO:0051495 positive regulation of cytoskeleton organization; GO:0016192 vesicle-mediated transport; GO:0043900 regulation of multi-organism process; GO:0032984 macromolecular complex disassembly; GO:1902188 positive regulation of viral release from host cell; GO:0071702 organic substance transport; GO:0010876 lipid localization; GO:0010033 response to organic substance; GO:0051656 establishment of organelle localization; GO:0044238 primary metabolic process; GO:0045184 establishment of protein localization; GO:1902186 regulation of viral release from host cell; GO:0019076 viral release from host cell; GO:0035890 exit from host; GO:0090224 regulation of spindle organization; GO:1903722 regulation of centriole elongation; GO:0051276 chromosome organization; GO:0006811 ion transport; GO:0006996 organelle organization; GO:0098813 nuclear chromosome segregation; GO:0061024 membrane organization; GO:0006900 membrane budding; GO:0000280 nuclear division; GO:0051179 localization; GO:0015672 monovalent inorganic cation transport; GO:0015850 organic hydroxy compound transport; GO:0010256 endomembrane system organization; GO:0040017 positive regulation of locomotion; GO:0030301 cholesterol transport; GO:0007067 mitotic nuclear division; GO:0044699 single-organism process; GO:0051046 regulation of secretion; GO:0044764 multi-organism cellular process; GO:0060236 regulation of mitotic spindle organization; GO:1902115 regulation of organelle assembly; GO:0043241 protein complex disassembly; GO:0051234 establishment of localization; GO:0046599 regulation of centriole replication; GO:0051130 positive regulation of cellular component organization; GO:0006813 potassium ion transport; GO:0051783 regulation of nuclear division; GO:0000819 sister chromatid segregation; GO:0050000 chromosome localization; GO:0051649 establishment of localization in cell; GO:1904896 ESCRT complex disassembly; GO:0022607 cellular component assembly; GO:0010825 positive regulation of centrosome duplication; GO:0007033 vacuole organization; GO:0033036 macromolecule localization; GO:1903542 negative regulation of exosomal secretion; GO:0051726 regulation of cell cycle; GO:0016236 macroautophagy; GO:1903902 positive regulation of viral life cycle; GO:0043902 positive regulation of multi-organism process; GO:0071822 protein complex subunit organization; GO:0048522 positive regulation of cellular process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0036257 multivesicular body organization; GO:1903530 regulation of secretion by cell; GO:0051050 positive regulation of transport; GO:0016197 endosomal transport; GO:1902589 single-organism organelle organization; GO:0051048 negative regulation of secretion; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:1903532 positive regulation of secretion by cell; GO:0010638 positive regulation of organelle organization; GO:1902117 positive regulation of organelle assembly; GO:0040011 locomotion; GO:0015918 sterol transport; GO:0006997 nucleus organization; GO:0016043 cellular component organization; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0019068 virion assembly; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0048285 organelle fission; GO:0019058 viral life cycle; GO:1902592 multi-organism membrane budding; GO:0044087 regulation of cellular component biogenesis; GO:0046601 positive regulation of centriole replication; GO:0051310 metaphase plate congression; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway; GO:0033993 response to lipid; GO:0006812 cation transport; GO:0070925 organelle assembly; GO:0016032 viral process; GO:0006508 proteolysis; GO:0009987 cellular process; GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; GO:0061738 late endosomal microautophagy; GO:0035891 exit from host cell; GO:0007041 lysosomal transport; GO:0051261 protein depolymerization; GO:0043632 modification-dependent macromolecule catabolic process; GO:0070507 regulation of microtubule cytoskeleton organization; GO:0044265 cellular macromolecule catabolic process; GO:0044803 multi-organism membrane organization; GO:0019941 modification-dependent protein catabolic process; GO:0051303 establishment of chromosome localization; GO:0046607 positive regulation of centrosome cycle; GO:0051049 regulation of transport; GO:0050792 regulation of viral process; GO:0000070 mitotic sister chromatid segregation; GO:0033043 regulation of organelle organization; GO:0016050 vesicle organization; GO:1902749 regulation of cell cycle G2/M phase transition; GO:0051701 interaction with host; GO:1902590 multi-organism organelle organization; GO:0048518 positive regulation of biological process; GO:0043933 macromolecular complex subunit organization; GO:0051641 cellular localization; GO:0090169 regulation of spindle assembly; GO:0048524 positive regulation of viral process; GO:0046755 viral budding; GO:0007034 vacuolar transport; GO:0009057 macromolecule catabolic process; GO:1904903 ESCRT III complex disassembly; GO:0022411 cellular component disassembly; GO:0022402 cell cycle process; GO:0051128 regulation of cellular component organization; GO:0010971 positive regulation of G2/M transition of mitotic cell cycle; GO:0040012 regulation of locomotion; GO:1903900 regulation of viral life cycle; GO:1901992 positive regulation of mitotic cell cycle phase transition; GO:0009056 catabolic process; GO:0007032 endosome organization; GO:0007049 cell cycle; GO:0044089 positive regulation of cellular component biogenesis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0005815 microtubule organizing center; GO:0015630 microtubule cytoskeleton; GO:0031902 late endosome membrane; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0090543 Flemming body; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0010008 endosome membrane; GO:0000922 spindle pole; GO:0005770 late endosome; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0030496 midbody; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0005829 cytosol; GO:0005819 spindle; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0005813 centrosome; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0046983 protein dimerization activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0016887 ATPase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0042802 identical protein binding; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0008022 protein C-terminus binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0042803 protein homodimerization activity; GO:0042623 ATPase activity, coupled; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; ","K12196","VPS4; vacuolar protein-sorting-associated protein 4","hsa04144 Endocytosis - Homo sapiens (human); hsa04217 Necroptosis - Homo sapiens (human); ","IPR003959; IPR003593; IPR015415; IPR027417; IPR007330; ","\"ATPase, AAA-type, core; AAA+ ATPase domain; Vps4 oligomerisation, C-terminal; P-loop containing nucleoside triphosphate hydrolase; MIT; \"\r"]
["O75367","Core histone macro-H2A.1 OS=Homo sapiens OX=9606 GN=H2AFY","H2AFY",39.617,32.856,15.9,6,10,6,1.035,1.058,1.065,0.934,0.951,0.946,0.896,0.000422,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:0034093 positive regulation of maintenance of sister chromatid cohesion; GO:0030858 positive regulation of epithelial cell differentiation; GO:0019216 regulation of lipid metabolic process; GO:0010564 regulation of cell cycle process; GO:0033127 regulation of histone phosphorylation; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0008152 metabolic process; GO:0006334 nucleosome assembly; GO:0051240 positive regulation of multicellular organismal process; GO:0045682 regulation of epidermis development; GO:0032879 regulation of localization; GO:0065003 macromolecular complex assembly; GO:0033365 protein localization to organelle; GO:0043170 macromolecule metabolic process; GO:0033128 negative regulation of histone phosphorylation; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0090068 positive regulation of cell cycle process; GO:0008104 protein localization; GO:0045815 positive regulation of gene expression, epigenetic; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0061085 regulation of histone H3-K27 methylation; GO:0080090 regulation of primary metabolic process; GO:0007088 regulation of mitotic nuclear division; GO:0000122 negative regulation of transcription from RNA polymerase II promoter; GO:0044763 single-organism cellular process; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0045840 positive regulation of mitotic nuclear division; GO:0071169 establishment of protein localization to chromatin; GO:0034091 regulation of maintenance of sister chromatid cohesion; GO:0065004 protein-DNA complex assembly; GO:1903506 regulation of nucleic acid-templated transcription; GO:0030856 regulation of epithelial cell differentiation; GO:0010948 negative regulation of cell cycle process; GO:0045931 positive regulation of mitotic cell cycle; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0048583 regulation of response to stimulus; GO:2001252 positive regulation of chromosome organization; GO:0010604 positive regulation of macromolecule metabolic process; GO:0031060 regulation of histone methylation; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0051094 positive regulation of developmental process; GO:0045876 positive regulation of sister chromatid cohesion; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0034502 protein localization to chromosome; GO:0050794 regulation of cellular process; GO:0034728 nucleosome organization; GO:0007346 regulation of mitotic cell cycle; GO:0031399 regulation of protein modification process; GO:0045604 regulation of epidermal cell differentiation; GO:0080134 regulation of response to stress; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0051239 regulation of multicellular organismal process; GO:0045597 positive regulation of cell differentiation; GO:0060341 regulation of cellular localization; GO:0045892 negative regulation of transcription, DNA-templated; GO:0006323 DNA packaging; GO:1902884 positive regulation of response to oxidative stress; GO:1901987 regulation of cell cycle phase transition; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0001933 negative regulation of protein phosphorylation; GO:0032880 regulation of protein localization; GO:0016569 covalent chromatin modification; GO:0051984 positive regulation of chromosome segregation; GO:0034613 cellular protein localization; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0045787 positive regulation of cell cycle; GO:1904814 regulation of protein localization to chromosome, telomeric region; GO:1902275 regulation of chromatin organization; GO:0034182 regulation of maintenance of mitotic sister chromatid cohesion; GO:0009892 negative regulation of metabolic process; GO:0033044 regulation of chromosome organization; GO:0031057 negative regulation of histone modification; GO:0045184 establishment of protein localization; GO:0045606 positive regulation of epidermal cell differentiation; GO:0071168 protein localization to chromatin; GO:0009890 negative regulation of biosynthetic process; GO:0051569 regulation of histone H3-K4 methylation; GO:2001251 negative regulation of chromosome organization; GO:0045618 positive regulation of keratinocyte differentiation; GO:0051276 chromosome organization; GO:0006996 organelle organization; GO:1902882 regulation of response to oxidative stress; GO:0051179 localization; GO:0043412 macromolecule modification; GO:0048584 positive regulation of response to stimulus; GO:0050793 regulation of developmental process; GO:0016479 negative regulation of transcription from RNA polymerase I promoter; GO:1903827 regulation of cellular protein localization; GO:0045936 negative regulation of phosphate metabolic process; GO:0072594 establishment of protein localization to organelle; GO:0051129 negative regulation of cellular component organization; GO:0051785 positive regulation of nuclear division; GO:0044699 single-organism process; GO:1901836 regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter; GO:0051253 negative regulation of RNA metabolic process; GO:0031400 negative regulation of protein modification process; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:2001141 regulation of RNA biosynthetic process; GO:0051783 regulation of nuclear division; GO:0071901 negative regulation of protein serine/threonine kinase activity; GO:0022607 cellular component assembly; GO:0009893 positive regulation of metabolic process; GO:0033673 negative regulation of kinase activity; GO:0033036 macromolecule localization; GO:0051726 regulation of cell cycle; GO:0031497 chromatin assembly; GO:0031061 negative regulation of histone methylation; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0071103 DNA conformation change; GO:0071824 protein-DNA complex subunit organization; GO:0010468 regulation of gene expression; GO:0006333 chromatin assembly or disassembly; GO:0033045 regulation of sister chromatid segregation; GO:1903828 negative regulation of cellular protein localization; GO:0031326 regulation of cellular biosynthetic process; GO:0033047 regulation of mitotic sister chromatid segregation; GO:0070199 establishment of protein localization to chromosome; GO:0048522 positive regulation of cellular process; GO:0061086 negative regulation of histone H3-K27 methylation; GO:0051348 negative regulation of transferase activity; GO:0010605 negative regulation of macromolecule metabolic process; GO:0034184 positive regulation of maintenance of mitotic sister chromatid cohesion; GO:0010639 negative regulation of organelle organization; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:1902883 negative regulation of response to oxidative stress; GO:0010638 positive regulation of organelle organization; GO:0006356 regulation of transcription from RNA polymerase I promoter; GO:1902679 negative regulation of RNA biosynthetic process; GO:0045616 regulation of keratinocyte differentiation; GO:0019222 regulation of metabolic process; GO:0006469 negative regulation of protein kinase activity; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0006325 chromatin organization; GO:0045814 negative regulation of gene expression, epigenetic; GO:0019220 regulation of phosphate metabolic process; GO:1905268 negative regulation of chromatin organization; GO:0043549 regulation of kinase activity; GO:2000026 regulation of multicellular organismal development; GO:0031056 regulation of histone modification; GO:0045859 regulation of protein kinase activity; GO:0016043 cellular component organization; GO:0045786 negative regulation of cell cycle; GO:0045684 positive regulation of epidermis development; GO:1901988 negative regulation of cell cycle phase transition; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0051572 negative regulation of histone H3-K4 methylation; GO:0071704 organic substance metabolic process; GO:0006342 chromatin silencing; GO:0007549 dosage compensation; GO:0042326 negative regulation of phosphorylation; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0051983 regulation of chromosome segregation; GO:0034622 cellular macromolecular complex assembly; GO:0006355 regulation of transcription, DNA-templated; GO:1904815 negative regulation of protein localization to chromosome, telomeric region; GO:0010629 negative regulation of gene expression; GO:0007063 regulation of sister chromatid cohesion; GO:0001932 regulation of protein phosphorylation; GO:0033043 regulation of organelle organization; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:1902749 regulation of cell cycle G2/M phase transition; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0043933 macromolecular complex subunit organization; GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter; GO:0040029 regulation of gene expression, epigenetic; GO:0070727 cellular macromolecule localization; GO:0016458 gene silencing; GO:0051246 regulation of protein metabolic process; GO:0010563 negative regulation of phosphorus metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:1902750 negative regulation of cell cycle G2/M phase transition; GO:0031327 negative regulation of cellular biosynthetic process; GO:0051128 regulation of cellular component organization; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0001740 Barr body; GO:0044421 extracellular region part; GO:0000784 nuclear chromosome, telomeric region; GO:0000781 chromosome, telomeric region; GO:0031982 vesicle; GO:0000803 sex chromosome; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0000792 heterochromatin; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0000793 condensed chromosome; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044454 nuclear chromosome part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005694 chromosome; GO:0000790 nuclear chromatin; GO:1903561 extracellular vesicle; GO:0005721 pericentric heterochromatin; GO:0043227 membrane-bounded organelle; GO:0044815 DNA packaging complex; GO:0032993 protein-DNA complex; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0001739 sex chromatin; GO:0000805 X chromosome; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005576 extracellular region; GO:0000786 nucleosome; GO:0005720 nuclear heterochromatin; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0098687 chromosomal region; GO:0005634 nucleus; GO:0000785 chromatin; GO:0000775 chromosome, centromeric region; GO:0000228 nuclear chromosome; GO:0043230 extracellular organelle; GO:0044428 nuclear part; ","GO:0030291 protein serine/threonine kinase inhibitor activity; GO:0000182 rDNA binding; GO:0031490 chromatin DNA binding; GO:0003690 double-stranded DNA binding; GO:0046983 protein dimerization activity; GO:0019901 protein kinase binding; GO:0005515 protein binding; GO:0004860 protein kinase inhibitor activity; GO:0003682 chromatin binding; GO:0019207 kinase regulator activity; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0001047 core promoter binding; GO:0000975 regulatory region DNA binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0001046 core promoter sequence-specific DNA binding; GO:0005488 binding; GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding; GO:0003677 DNA binding; GO:0010385 double-stranded methylated DNA binding; GO:0046982 protein heterodimerization activity; GO:0000976 transcription regulatory region sequence-specific DNA binding; GO:0044877 macromolecular complex binding; GO:1990837 sequence-specific double-stranded DNA binding; GO:0001012 RNA polymerase II regulatory region DNA binding; GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding; GO:0019887 protein kinase regulator activity; GO:0043565 sequence-specific DNA binding; GO:0019900 kinase binding; GO:0001067 regulatory region nucleic acid binding; GO:0030234 enzyme regulator activity; GO:0019210 kinase inhibitor activity; GO:0044212 transcription regulatory region DNA binding; GO:0003676 nucleic acid binding; GO:0031491 nucleosome binding; GO:0019899 enzyme binding; GO:0031492 nucleosomal DNA binding; ","K11251","H2A; histone H2A","hsa05322 Systemic lupus erythematosus - Homo sapiens (human); hsa05034 Alcoholism - Homo sapiens (human); hsa04217 Necroptosis - Homo sapiens (human); ","IPR002589; IPR032454; IPR009072; IPR007125; ","\"Macro domain; Histone H2A, C-terminal domain; Histone-fold; Histone H2A/H2B/H3; \"\r"]
["O75368","SH3 domain-binding glutamic acid-rich-like protein OS=Homo sapiens OX=9606 GN=SH3BGRL","SH3BGRL",12.774,86.696,85.1,10,20,10,1.049,1.104,1.076,0.911,0.961,0.947,0.873,0.00334,"mitochondria\r","GO:0050794 regulation of cellular process; GO:0050789 regulation of biological process; GO:0010646 regulation of cell communication; GO:0023056 positive regulation of signaling; GO:0023051 regulation of signaling; GO:0048583 regulation of response to stimulus; GO:0048522 positive regulation of cellular process; GO:0009967 positive regulation of signal transduction; GO:0010647 positive regulation of cell communication; GO:0048584 positive regulation of response to stimulus; GO:0009966 regulation of signal transduction; GO:0048518 positive regulation of biological process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0005070 SH3/SH2 adaptor activity; GO:0030674 protein binding, bridging; GO:0035591 signaling adaptor activity; GO:0005488 binding; GO:0060090 binding, bridging; GO:0005515 protein binding; GO:0019904 protein domain specific binding; GO:0017124 SH3 domain binding; ",{"$nulls":3},"IPR012336; ","Thioredoxin-like fold; \r"]
["O75369","Filamin-B OS=Homo sapiens OX=9606 GN=FLNB","FLNB",278.16,323.31,40.3,89,162,77,1.045,1.072,1.06,0.953,0.939,0.933,0.889,2.63E-4,"cyto_nucl\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0048869 cellular developmental process; GO:0032989 cellular component morphogenesis; GO:0044699 single-organism process; GO:0009913 epidermal cell differentiation; GO:0007165 signal transduction; GO:0030036 actin cytoskeleton organization; GO:0007154 cell communication; GO:0008544 epidermis development; GO:0051651 maintenance of location in cell; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0007519 skeletal muscle tissue development; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0060429 epithelium development; GO:0043588 skin development; GO:0002064 epithelial cell development; GO:0032507 maintenance of protein location in cell; GO:0030216 keratinocyte differentiation; GO:0009888 tissue development; GO:0060537 muscle tissue development; GO:0044763 single-organism cellular process; GO:0023052 signaling; GO:0060538 skeletal muscle organ development; GO:0032501 multicellular organismal process; GO:0000902 cell morphogenesis; GO:1902589 single-organism organelle organization; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0007517 muscle organ development; GO:0048856 anatomical structure development; GO:0030855 epithelial cell differentiation; GO:0050794 regulation of cellular process; GO:0014706 striated muscle tissue development; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0007016 cytoskeletal anchoring at plasma membrane; GO:0003334 keratinocyte development; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0000904 cell morphogenesis involved in differentiation; GO:0009653 anatomical structure morphogenesis; GO:0030154 cell differentiation; GO:1902578 single-organism localization; GO:0061061 muscle structure development; GO:0051235 maintenance of location; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0045185 maintenance of protein location; GO:0048731 system development; GO:0051641 cellular localization; GO:0070727 cellular macromolecule localization; GO:0003382 epithelial cell morphogenesis; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0030029 actin filament-based process; GO:0051179 localization; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0098862 cluster of actin-based cell projections; GO:0005903 brush border; GO:0005938 cell cortex; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0030016 myofibril; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0099568 cytoplasmic region; GO:0031224 intrinsic component of membrane; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0030018 Z disc; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0031674 I band; GO:0032432 actin filament bundle; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005856 cytoskeleton; GO:0005925 focal adhesion; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0043292 contractile fiber; GO:0001725 stress fiber; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0042641 actomyosin; GO:0005924 cell-substrate adherens junction; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0097517 contractile actin filament bundle; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0015629 actin cytoskeleton; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0099081 supramolecular polymer; GO:0031012 extracellular matrix; GO:0043226 organelle; GO:0030017 sarcomere; GO:0044449 contractile fiber part; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0050839 cell adhesion molecule binding; GO:0003723 RNA binding; GO:0008092 cytoskeletal protein binding; GO:0042802 identical protein binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0003676 nucleic acid binding; GO:0003779 actin binding; GO:0005515 protein binding; ","K04437","FLNA; filamin","hsa05132 Salmonella infection - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa04010 MAPK signaling pathway - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); ","IPR013783; IPR014756; IPR001715; ","Immunoglobulin-like fold; Immunoglobulin E-set; Calponin homology domain; \r"]
["O75380","NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS6","NDUFS6",13.711,8.1014,23.4,2,2,2,0.923,0.882,1.187,0.77,1.242,0.986,1.002,0.963,"extracellular\r","GO:0044085 cellular component biogenesis; GO:0003012 muscle system process; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0048869 cellular developmental process; GO:0009117 nucleotide metabolic process; GO:0032989 cellular component morphogenesis; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0022607 cellular component assembly; GO:0032990 cell part morphogenesis; GO:0065003 macromolecular complex assembly; GO:0006753 nucleoside phosphate metabolic process; GO:0007005 mitochondrion organization; GO:0032787 monocarboxylic acid metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0006629 lipid metabolic process; GO:0032502 developmental process; GO:0010259 multicellular organism aging; GO:0071822 protein complex subunit organization; GO:0010257 NADH dehydrogenase complex assembly; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0006119 oxidative phosphorylation; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0006120 mitochondrial electron transport, NADH to ubiquinone; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0032501 multicellular organismal process; GO:1902589 single-organism organelle organization; GO:0097031 mitochondrial respiratory chain complex I biogenesis; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0007568 aging; GO:0022900 electron transport chain; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0070271 protein complex biogenesis; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:0033108 mitochondrial respiratory chain complex assembly; GO:0043436 oxoacid metabolic process; GO:0072359 circulatory system development; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0016310 phosphorylation; GO:0006725 cellular aromatic compound metabolic process; GO:0042773 ATP synthesis coupled electron transport; GO:0009259 ribonucleotide metabolic process; GO:0022904 respiratory electron transport chain; GO:0070584 mitochondrion morphogenesis; GO:0071704 organic substance metabolic process; GO:0032981 mitochondrial respiratory chain complex I assembly; GO:0009653 anatomical structure morphogenesis; GO:0006936 muscle contraction; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0035264 multicellular organism growth; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0061458 reproductive system development; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0009119 ribonucleoside metabolic process; GO:0006461 protein complex assembly; GO:0043623 cellular protein complex assembly; GO:0046034 ATP metabolic process; GO:0034622 cellular macromolecular complex assembly; GO:0003008 system process; GO:0048731 system development; GO:0006807 nitrogen compound metabolic process; GO:0072358 cardiovascular system development; GO:0009141 nucleoside triphosphate metabolic process; GO:0006631 fatty acid metabolic process; GO:0044238 primary metabolic process; GO:0045333 cellular respiration; GO:0006163 purine nucleotide metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0046128 purine ribonucleoside metabolic process; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0019752 carboxylic acid metabolic process; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0048589 developmental growth; GO:0040007 growth; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:0071840 cellular component organization or biogenesis; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0045271 respiratory chain complex I; GO:0044424 intracellular part; GO:0098798 mitochondrial protein complex; GO:0005747 mitochondrial respiratory chain complex I; GO:0005623 cell; GO:0044455 mitochondrial membrane part; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:1902494 catalytic complex; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0098803 respiratory chain complex; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005739 mitochondrion; GO:0005746 mitochondrial respiratory chain; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0030964 NADH dehydrogenase complex; GO:1990204 oxidoreductase complex; GO:0031975 envelope; GO:0043234 protein complex; GO:0031966 mitochondrial membrane; GO:0070469 respiratory chain; GO:0044444 cytoplasmic part; ","GO:0009055 electron carrier activity; GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:0003954 NADH dehydrogenase activity; GO:0003824 catalytic activity; GO:0050136 NADH dehydrogenase (quinone) activity; GO:0008137 NADH dehydrogenase (ubiquinone) activity; GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; GO:0016491 oxidoreductase activity; ","K03939","NDUFS6; NADH dehydrogenase (ubiquinone) Fe-S protein 6","hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); ","IPR019401; ","\"Zinc finger, CHCC-type; \"\r"]
["O75390","Citrate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=CS","CS",51.712,66.253,29.2,13,38,13,1.055,1.032,1.029,0.974,0.961,0.98,0.935,0.00242,"mitochondria\r","GO:0072350 tricarboxylic acid metabolic process; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0006099 tricarboxylic acid cycle; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0005975 carbohydrate metabolic process; GO:0044238 primary metabolic process; GO:0045333 cellular respiration; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0006101 citrate metabolic process; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0009060 aerobic respiration; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0019752 carboxylic acid metabolic process; GO:0006082 organic acid metabolic process; GO:0009987 cellular process; GO:0043436 oxoacid metabolic process; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0036440 citrate synthase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0016746 transferase activity, transferring acyl groups; GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer; GO:0003824 catalytic activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0016740 transferase activity; GO:0004108 citrate (Si)-synthase activity; ","K01647","CS; citrate synthase [EC:2.3.3.1]","hsa01210 2-Oxocarboxylic acid metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00020 Citrate cycle (TCA cycle) - Homo sapiens (human); hsa01230 Biosynthesis of amino acids - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); hsa00630 Glyoxylate and dicarboxylate metabolism - Homo sapiens (human); ","IPR016142; ","\"Citrate synthase-like, large alpha subdomain; \"\r"]
["O75396","Vesicle-trafficking protein SEC22b OS=Homo sapiens OX=9606 GN=SEC22B","SEC22B",24.593,59.549,39.1,9,16,9,1.069,1.085,1.069,0.976,0.931,0.917,0.876,0.00242,"E.R._mito\r","GO:0044085 cellular component biogenesis; GO:1990668 vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane; GO:0006901 vesicle coating; GO:0048207 vesicle targeting, rough ER to cis-Golgi; GO:0048208 COPII vesicle coating; GO:0044699 single-organism process; GO:0048280 vesicle fusion with Golgi apparatus; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0051649 establishment of localization in cell; GO:0009893 positive regulation of metabolic process; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0048199 vesicle targeting, to, from or within Golgi; GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0044801 single-organism membrane fusion; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0051650 establishment of vesicle localization; GO:0071822 protein complex subunit organization; GO:0080090 regulation of primary metabolic process; GO:0048002 antigen processing and presentation of peptide antigen; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0061025 membrane fusion; GO:0006810 transport; GO:0019884 antigen processing and presentation of exogenous antigen; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0019222 regulation of metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006906 vesicle fusion; GO:0070271 protein complex biogenesis; GO:0051640 organelle localization; GO:0050794 regulation of cellular process; GO:0090174 organelle membrane fusion; GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0060255 regulation of macromolecule metabolic process; GO:0048193 Golgi vesicle transport; GO:0006903 vesicle targeting; GO:0051648 vesicle localization; GO:0009896 positive regulation of catabolic process; GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; GO:0042176 regulation of protein catabolic process; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0090114 COPII-coated vesicle budding; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:0016192 vesicle-mediated transport; GO:0016050 vesicle organization; GO:0044802 single-organism membrane organization; GO:0033043 regulation of organelle organization; GO:0002376 immune system process; GO:0048284 organelle fusion; GO:0071702 organic substance transport; GO:0051656 establishment of organelle localization; GO:0048518 positive regulation of biological process; GO:0043933 macromolecular complex subunit organization; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0019882 antigen processing and presentation; GO:0051247 positive regulation of protein metabolic process; GO:0006890 retrograde vesicle-mediated transport, Golgi to ER; GO:0006996 organelle organization; GO:0051246 regulation of protein metabolic process; GO:0061024 membrane organization; GO:0006900 membrane budding; GO:0045732 positive regulation of protein catabolic process; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0030658 transport vesicle membrane; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0030662 coated vesicle membrane; GO:0044422 organelle part; GO:0048770 pigment granule; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0030670 phagocytic vesicle membrane; GO:0098805 whole membrane; GO:0044431 Golgi apparatus part; GO:0030139 endocytic vesicle; GO:0043227 membrane-bounded organelle; GO:0031201 SNARE complex; GO:0005789 endoplasmic reticulum membrane; GO:0012507 ER to Golgi transport vesicle membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0030666 endocytic vesicle membrane; GO:0042470 melanosome; GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0030134 ER to Golgi transport vesicle; GO:0012506 vesicle membrane; GO:0045335 phagocytic vesicle; GO:0012505 endomembrane system; GO:0030135 coated vesicle; GO:0016021 integral component of membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044432 endoplasmic reticulum part; GO:0005793 endoplasmic reticulum-Golgi intermediate compartment; GO:0043234 protein complex; GO:0030133 transport vesicle; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:0000149 SNARE binding; GO:0005484 SNAP receptor activity; GO:0005515 protein binding; GO:0019905 syntaxin binding; GO:0005488 binding; ","K08517","SEC22; vesicle transport protein SEC22","hsa05134 Legionellosis - Homo sapiens (human); hsa04130 SNARE interactions in vesicular transport - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); ","IPR010908; IPR011012; IPR001388; ","Longin domain; Longin-like domain; Synaptobrevin; \r"]
["O75400","Pre-mRNA-processing factor 40 homolog A OS=Homo sapiens OX=9606 GN=PRPF40A","PRPF40A",108.8,17.93,7.6,7,8,7,0.894,0.886,0.903,1.143,1.055,1.111,1.233,0.000964,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0016477 cell migration; GO:0065008 regulation of biological quality; GO:0006725 cellular aromatic compound metabolic process; GO:0051674 localization of cell; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0010564 regulation of cell cycle process; GO:0032465 regulation of cytokinesis; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0008152 metabolic process; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0008360 regulation of cell shape; GO:0000375 RNA splicing, via transesterification reactions; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0007010 cytoskeleton organization; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0051726 regulation of cell cycle; GO:0006396 RNA processing; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0048870 cell motility; GO:0044238 primary metabolic process; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:0050789 regulation of biological process; GO:0051302 regulation of cell division; GO:0090304 nucleic acid metabolic process; GO:0006996 organelle organization; GO:0022603 regulation of anatomical structure morphogenesis; GO:0044260 cellular macromolecule metabolic process; GO:0006928 movement of cell or subcellular component; GO:0010467 gene expression; GO:0051301 cell division; GO:0051128 regulation of cellular component organization; GO:0040011 locomotion; GO:0051179 localization; GO:0022604 regulation of cell morphogenesis; GO:0050793 regulation of developmental process; GO:0016071 mRNA metabolic process; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0005685 U1 snRNP; GO:0016020 membrane; GO:0005737 cytoplasm; GO:0005684 U2-type spliceosomal complex; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0044464 cell part; GO:0005622 intracellular; GO:0071004 U2-type prespliceosome; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005681 spliceosomal complex; GO:0005829 cytosol; GO:0097525 spliceosomal snRNP complex; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0016363 nuclear matrix; GO:0071010 prespliceosome; GO:1990904 ribonucleoprotein complex; GO:0034399 nuclear periphery; GO:0030532 small nuclear ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0070064 proline-rich region binding; ","K12821","PRPF40; pre-mRNA-processing factor 40","hsa03040 Spliceosome - Homo sapiens (human); ","IPR002713; IPR001202; ","FF domain; WW domain; \r"]
["O75436","Vacuolar protein sorting-associated protein 26A OS=Homo sapiens OX=9606 GN=VPS26A","VPS26A",38.169,57.673,28.1,9,12,8,0.963,0.896,0.974,1.044,1.023,0.976,1.074,0.0944,"cytoplasm\r","GO:0044700 single organism signaling; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0007166 cell surface receptor signaling pathway; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0006886 intracellular protein transport; GO:1990126 retrograde transport, endosome to plasma membrane; GO:0016055 Wnt signaling pathway; GO:0034613 cellular protein localization; GO:0016482 cytosolic transport; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0009987 cellular process; GO:0051716 cellular response to stimulus; GO:0098876 vesicle-mediated transport to the plasma membrane; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0071702 organic substance transport; GO:0023052 signaling; GO:0031323 regulation of cellular metabolic process; GO:0010506 regulation of autophagy; GO:0198738 cell-cell signaling by wnt; GO:0051641 cellular localization; GO:0016241 regulation of macroautophagy; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:0016197 endosomal transport; GO:0070727 cellular macromolecule localization; GO:0050789 regulation of biological process; GO:0007267 cell-cell signaling; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0042147 retrograde transport, endosome to Golgi; GO:0019222 regulation of metabolic process; GO:0051179 localization; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0030904 retromer complex; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0030906 retromer, cargo-selective complex; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005764 lysosome; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0000323 lytic vacuole; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0010008 endosome membrane; GO:0097422 tubular endosome; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005773 vacuole; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0008565 protein transporter activity; GO:0005488 binding; GO:0005215 transporter activity; ","K18466","VPS26; vacuolar protein sorting-associated protein 26","hsa04144 Endocytosis - Homo sapiens (human); "]
["O75438","NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 OS=Homo sapiens OX=9606 GN=NDUFB1","NDUFB1",6.9611,9.6761,32.8,2,4,2,1.072,1.014,1.06,0.969,0.965,0.971,0.923,0.0433,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0022607 cellular component assembly; GO:0006753 nucleoside phosphate metabolic process; GO:0065003 macromolecular complex assembly; GO:0007005 mitochondrion organization; GO:0019693 ribose phosphate metabolic process; GO:0071822 protein complex subunit organization; GO:0010257 NADH dehydrogenase complex assembly; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0006119 oxidative phosphorylation; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0006120 mitochondrial electron transport, NADH to ubiquinone; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0097031 mitochondrial respiratory chain complex I biogenesis; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0022900 electron transport chain; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0070271 protein complex biogenesis; GO:0033108 mitochondrial respiratory chain complex assembly; GO:0016043 cellular component organization; GO:0016310 phosphorylation; GO:0006725 cellular aromatic compound metabolic process; GO:0042773 ATP synthesis coupled electron transport; GO:0009259 ribonucleotide metabolic process; GO:0022904 respiratory electron transport chain; GO:0071704 organic substance metabolic process; GO:0032981 mitochondrial respiratory chain complex I assembly; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0009119 ribonucleoside metabolic process; GO:0006461 protein complex assembly; GO:0043623 cellular protein complex assembly; GO:0046034 ATP metabolic process; GO:0034622 cellular macromolecular complex assembly; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0045333 cellular respiration; GO:0006163 purine nucleotide metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0046128 purine ribonucleoside metabolic process; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:1901564 organonitrogen compound metabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0045271 respiratory chain complex I; GO:0032991 macromolecular complex; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0005747 mitochondrial respiratory chain complex I; GO:0044455 mitochondrial membrane part; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0016607 nuclear speck; GO:0019866 organelle inner membrane; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0098803 respiratory chain complex; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005746 mitochondrial respiratory chain; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0030964 NADH dehydrogenase complex; GO:0031975 envelope; GO:1990204 oxidoreductase complex; GO:0043234 protein complex; GO:0031966 mitochondrial membrane; GO:0070469 respiratory chain; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:0003954 NADH dehydrogenase activity; GO:0003824 catalytic activity; GO:0050136 NADH dehydrogenase (quinone) activity; GO:0008137 NADH dehydrogenase (ubiquinone) activity; GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; GO:0016491 oxidoreductase activity; ","K03957","NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1","hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); "]
["O75439","Mitochondrial-processing peptidase subunit beta OS=Homo sapiens OX=9606 GN=PMPCB","PMPCB",54.366,11.751,7.8,4,5,3,1.029,1.076,0.893,1.009,0.959,1.055,1.008,0.873,"mitochondria\r","GO:0016310 phosphorylation; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0042773 ATP synthesis coupled electron transport; GO:0009259 ribonucleotide metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0022904 respiratory electron transport chain; GO:0016485 protein processing; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0006139 nucleobase-containing compound metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0019693 ribose phosphate metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0006508 proteolysis; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0009119 ribonucleoside metabolic process; GO:0009987 cellular process; GO:0046034 ATP metabolic process; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0006119 oxidative phosphorylation; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0045333 cellular respiration; GO:0006163 purine nucleotide metabolic process; GO:0046128 purine ribonucleoside metabolic process; GO:0006793 phosphorus metabolic process; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0009060 aerobic respiration; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0019637 organophosphate metabolic process; GO:0022900 electron transport chain; GO:0010467 gene expression; GO:0009150 purine ribonucleotide metabolic process; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0051604 protein maturation; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:1901564 organonitrogen compound metabolic process; GO:0009123 nucleoside monophosphate metabolic process; ","GO:0016020 membrane; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0005750 mitochondrial respiratory chain complex III; GO:0044464 cell part; GO:0005622 intracellular; GO:0019866 organelle inner membrane; GO:1990351 transporter complex; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0098803 respiratory chain complex; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005759 mitochondrial matrix; GO:0044429 mitochondrial part; GO:0070069 cytochrome complex; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:1902495 transmembrane transporter complex; GO:0016021 integral component of membrane; GO:0045275 respiratory chain complex III; GO:0005739 mitochondrion; GO:0005746 mitochondrial respiratory chain; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:1990204 oxidoreductase complex; GO:0031975 envelope; GO:0043234 protein complex; GO:0070469 respiratory chain; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0004175 endopeptidase activity; GO:0004222 metalloendopeptidase activity; GO:0008233 peptidase activity; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0016787 hydrolase activity; GO:0008237 metallopeptidase activity; GO:0008270 zinc ion binding; ","K17732",null,null,"IPR007863; IPR011765; IPR011249; IPR011237; ","\"Peptidase M16, C-terminal; Peptidase M16, N-terminal; Metalloenzyme, LuxS/M16 peptidase-like; Peptidase M16 domain; \"\r"]
["O75475","PC4 and SFRS1-interacting protein OS=Homo sapiens OX=9606 GN=PSIP1","PSIP1",60.103,23.203,18.1,9,11,8,1.05,1,1.008,0.94,0.986,1.021,0.964,0.258,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0022618 ribonucleoprotein complex assembly; GO:0019043 establishment of viral latency; GO:0097659 nucleic acid-templated transcription; GO:0009891 positive regulation of biosynthetic process; GO:0009058 biosynthetic process; GO:0051169 nuclear transport; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0071826 ribonucleoprotein complex subunit organization; GO:0000395 mRNA 5'-splice site recognition; GO:0009893 positive regulation of metabolic process; GO:0022607 cellular component assembly; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0009408 response to heat; GO:0065003 macromolecular complex assembly; GO:0006979 response to oxidative stress; GO:0019042 viral latency; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0006396 RNA processing; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0075713 establishment of integrated proviral latency; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0031323 regulation of cellular metabolic process; GO:0051704 multi-organism process; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:0006810 transport; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0006376 mRNA splice site selection; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0045292 mRNA cis splicing, via spliceosome; GO:0009628 response to abiotic stimulus; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0010628 positive regulation of gene expression; GO:0016032 viral process; GO:0009889 regulation of biosynthetic process; GO:0009266 response to temperature stimulus; GO:0000375 RNA splicing, via transesterification reactions; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0008380 RNA splicing; GO:0034622 cellular macromolecular complex assembly; GO:0051254 positive regulation of RNA metabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0006950 response to stress; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:1901576 organic substance biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0051641 cellular localization; GO:0043933 macromolecular complex subunit organization; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0031325 positive regulation of cellular metabolic process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0010467 gene expression; GO:0031328 positive regulation of cellular biosynthetic process; GO:0051179 localization; GO:0000245 spliceosomal complex assembly; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0000792 heterochromatin; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044454 nuclear chromosome part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0000790 nuclear chromatin; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005720 nuclear heterochromatin; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0000785 chromatin; GO:0035327 transcriptionally active chromatin; GO:0000228 nuclear chromosome; GO:0034399 nuclear periphery; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0003677 DNA binding; GO:0003723 RNA binding; GO:0003690 double-stranded DNA binding; GO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding; GO:0005515 protein binding; GO:0003682 chromatin binding; GO:0003712 transcription cofactor activity; GO:0033613 activating transcription factor binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0001104 RNA polymerase II transcription cofactor activity; GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding; GO:0001105 RNA polymerase II transcription coactivator activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0098811 transcriptional repressor activity, RNA polymerase II activating transcription factor binding; GO:0003713 transcription coactivator activity; GO:0097100 supercoiled DNA binding; GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding; GO:0000988 transcription factor activity, protein binding; GO:0008134 transcription factor binding; ",{"$nulls":3},"IPR000313; ","PWWP domain; \r"]
["O75477","Erlin-1 OS=Homo sapiens OX=9606 GN=ERLIN1","ERLIN1",38.925,19.775,23.1,7,12,4,0.941,1.032,0.982,1.01,0.971,1.07,1.032,0.457,"extracellular\r","GO:0044700 single organism signaling; GO:0006066 alcohol metabolic process; GO:0009891 positive regulation of biosynthetic process; GO:0044699 single-organism process; GO:0036503 ERAD pathway; GO:0019216 regulation of lipid metabolic process; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0090206 negative regulation of cholesterol metabolic process; GO:0030433 ubiquitin-dependent ERAD pathway; GO:0007154 cell communication; GO:0050810 regulation of steroid biosynthetic process; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:1902931 negative regulation of alcohol biosynthetic process; GO:0090181 regulation of cholesterol metabolic process; GO:0045922 negative regulation of fatty acid metabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0006629 lipid metabolic process; GO:0045833 negative regulation of lipid metabolic process; GO:0051055 negative regulation of lipid biosynthetic process; GO:0010468 regulation of gene expression; GO:0051716 cellular response to stimulus; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0008202 steroid metabolic process; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0031323 regulation of cellular metabolic process; GO:0023052 signaling; GO:0010565 regulation of cellular ketone metabolic process; GO:0006810 transport; GO:0045939 negative regulation of steroid metabolic process; GO:1901575 organic substance catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0030163 protein catabolic process; GO:0044710 single-organism metabolic process; GO:0046890 regulation of lipid biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0042304 regulation of fatty acid biosynthetic process; GO:0019222 regulation of metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0034976 response to endoplasmic reticulum stress; GO:1901615 organic hydroxy compound metabolic process; GO:1902652 secondary alcohol metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0032933 SREBP signaling pathway; GO:0044267 cellular protein metabolic process; GO:0019218 regulation of steroid metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:1902930 regulation of alcohol biosynthetic process; GO:0050896 response to stimulus; GO:0016125 sterol metabolic process; GO:0010498 proteasomal protein catabolic process; GO:0071704 organic substance metabolic process; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0044248 cellular catabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0006508 proteolysis; GO:1902680 positive regulation of RNA biosynthetic process; GO:0009987 cellular process; GO:0043632 modification-dependent macromolecule catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0008203 cholesterol metabolic process; GO:0051254 positive regulation of RNA metabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0006950 response to stress; GO:0019941 modification-dependent protein catabolic process; GO:0044712 single-organism catabolic process; GO:0045540 regulation of cholesterol biosynthetic process; GO:0071501 cellular response to sterol depletion; GO:0006991 response to sterol depletion; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0006984 ER-nucleus signaling pathway; GO:0009892 negative regulation of metabolic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0019217 regulation of fatty acid metabolic process; GO:0055085 transmembrane transport; GO:0009890 negative regulation of biosynthetic process; GO:0010894 negative regulation of steroid biosynthetic process; GO:0009057 macromolecule catabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0045541 negative regulation of cholesterol biosynthetic process; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0045717 negative regulation of fatty acid biosynthetic process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0051179 localization; GO:0031328 positive regulation of cellular biosynthetic process; GO:0009056 catabolic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044432 endoplasmic reticulum part; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:0015485 cholesterol binding; GO:0032934 sterol binding; GO:0031625 ubiquitin protein ligase binding; GO:0005488 binding; GO:0043178 alcohol binding; GO:0008289 lipid binding; GO:0005515 protein binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0019899 enzyme binding; GO:0005496 steroid binding; GO:0036094 small molecule binding; ",{"$nulls":3},"IPR001107; ","Band 7 domain; \r"]
["O75489","NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS3","NDUFS3",30.241,68.983,40.9,10,15,10,1.031,1.049,0.978,1.018,1.004,0.987,0.984,0.528,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:0010941 regulation of cell death; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009968 negative regulation of signal transduction; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0007420 brain development; GO:0023051 regulation of signaling; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0048857 neural nucleus development; GO:0001558 regulation of cell growth; GO:2001233 regulation of apoptotic signaling pathway; GO:0021762 substantia nigra development; GO:0008152 metabolic process; GO:0010646 regulation of cell communication; GO:2001243 negative regulation of intrinsic apoptotic signaling pathway; GO:0006091 generation of precursor metabolites and energy; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0006753 nucleoside phosphate metabolic process; GO:0007005 mitochondrion organization; GO:0019693 ribose phosphate metabolic process; GO:0060322 head development; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0045926 negative regulation of growth; GO:0030901 midbrain development; GO:0071822 protein complex subunit organization; GO:0010257 NADH dehydrogenase complex assembly; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006119 oxidative phosphorylation; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0006120 mitochondrial electron transport, NADH to ubiquinone; GO:0032501 multicellular organismal process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0030308 negative regulation of cell growth; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0097031 mitochondrial respiratory chain complex I biogenesis; GO:1902532 negative regulation of intracellular signal transduction; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0007417 central nervous system development; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:0015980 energy derivation by oxidation of organic compounds; GO:0022900 electron transport chain; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0070271 protein complex biogenesis; GO:0060548 negative regulation of cell death; GO:0048856 anatomical structure development; GO:0033108 mitochondrial respiratory chain complex assembly; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0016310 phosphorylation; GO:0016043 cellular component organization; GO:0043069 negative regulation of programmed cell death; GO:0040008 regulation of growth; GO:0006725 cellular aromatic compound metabolic process; GO:0042773 ATP synthesis coupled electron transport; GO:0009259 ribonucleotide metabolic process; GO:0043067 regulation of programmed cell death; GO:0022904 respiratory electron transport chain; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0071704 organic substance metabolic process; GO:0032981 mitochondrial respiratory chain complex I assembly; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0046483 heterocycle metabolic process; GO:0072593 reactive oxygen species metabolic process; GO:0043066 negative regulation of apoptotic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009966 regulation of signal transduction; GO:0009119 ribonucleoside metabolic process; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0043623 cellular protein complex assembly; GO:0046034 ATP metabolic process; GO:0034622 cellular macromolecular complex assembly; GO:1902531 regulation of intracellular signal transduction; GO:0048731 system development; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0048585 negative regulation of response to stimulus; GO:0044238 primary metabolic process; GO:0045333 cellular respiration; GO:0006163 purine nucleotide metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0046128 purine ribonucleoside metabolic process; GO:0006793 phosphorus metabolic process; GO:0044767 single-organism developmental process; GO:0006996 organelle organization; GO:2001242 regulation of intrinsic apoptotic signaling pathway; GO:0019637 organophosphate metabolic process; GO:0051128 regulation of cellular component organization; GO:0009150 purine ribonucleotide metabolic process; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0045271 respiratory chain complex I; GO:0032991 macromolecular complex; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0005747 mitochondrial respiratory chain complex I; GO:0016604 nuclear body; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0043209 myelin sheath; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0044451 nucleoplasm part; GO:0098803 respiratory chain complex; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005759 mitochondrial matrix; GO:0044429 mitochondrial part; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0031981 nuclear lumen; GO:0005739 mitochondrion; GO:0005746 mitochondrial respiratory chain; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0030964 NADH dehydrogenase complex; GO:0031975 envelope; GO:1990204 oxidoreductase complex; GO:0043234 protein complex; GO:0031966 mitochondrial membrane; GO:0070469 respiratory chain; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0009055 electron carrier activity; GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:0003954 NADH dehydrogenase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0050136 NADH dehydrogenase (quinone) activity; GO:0005515 protein binding; GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; GO:0008137 NADH dehydrogenase (ubiquinone) activity; GO:0016491 oxidoreductase activity; ","K03936","NDUFS3; NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:1.6.5.3 1.6.99.3]","hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); ","IPR001268; ","\"NADH:ubiquinone oxidoreductase, 30kDa subunit; \"\r"]
["O75503","Ceroid-lipofuscinosis neuronal protein 5 OS=Homo sapiens OX=9606 GN=CLN5","CLN5",41.496,3.1136,2.5,1,1,1,0.966,1.208,0.91,0.954,1.031,0.948,0.951,0.656,"cytoplasm\r","GO:0021700 developmental maturation; GO:0065008 regulation of biological quality; GO:0035751 regulation of lysosomal lumen pH; GO:0006518 peptide metabolic process; GO:0007420 brain development; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0006465 signal peptide processing; GO:0030641 regulation of cellular pH; GO:0030004 cellular monovalent inorganic cation homeostasis; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0016485 protein processing; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0044093 positive regulation of molecular function; GO:0048469 cell maturation; GO:0060322 head development; GO:0007033 vacuole organization; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0051099 positive regulation of binding; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0050801 ion homeostasis; GO:0048699 generation of neurons; GO:1904424 regulation of GTP binding; GO:0098771 inorganic ion homeostasis; GO:0051098 regulation of binding; GO:0044763 single-organism cellular process; GO:0019725 cellular homeostasis; GO:0043603 cellular amide metabolic process; GO:0032501 multicellular organismal process; GO:0007040 lysosome organization; GO:0006810 transport; GO:0016197 endosomal transport; GO:1901575 organic substance catabolic process; GO:0048513 animal organ development; GO:0042147 retrograde transport, endosome to Golgi; GO:0044710 single-organism metabolic process; GO:0030163 protein catabolic process; GO:0007417 central nervous system development; GO:0044260 cellular macromolecule metabolic process; GO:0065009 regulation of molecular function; GO:0042551 neuron maturation; GO:0048856 anatomical structure development; GO:0044707 single-multicellular organism process; GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0045851 pH reduction; GO:0006885 regulation of pH; GO:0007035 vacuolar acidification; GO:0030003 cellular cation homeostasis; GO:0044267 cellular protein metabolic process; GO:0048468 cell development; GO:0055082 cellular chemical homeostasis; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:1904426 positive regulation of GTP binding; GO:0030154 cell differentiation; GO:0055080 cation homeostasis; GO:0034641 cellular nitrogen compound metabolic process; GO:0006508 proteolysis; GO:0007042 lysosomal lumen acidification; GO:0007275 multicellular organism development; GO:0016482 cytosolic transport; GO:0009987 cellular process; GO:0070085 glycosylation; GO:0048878 chemical homeostasis; GO:0055067 monovalent inorganic cation homeostasis; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:0051641 cellular localization; GO:0030182 neuron differentiation; GO:0051453 regulation of intracellular pH; GO:0006873 cellular ion homeostasis; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0009057 macromolecule catabolic process; GO:0080171 lytic vacuole organization; GO:0010467 gene expression; GO:0051452 intracellular pH reduction; GO:0051604 protein maturation; GO:0051179 localization; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005765 lysosomal membrane; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0043227 membrane-bounded organelle; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0030246 carbohydrate binding; GO:0005515 protein binding; GO:0048029 monosaccharide binding; GO:0005488 binding; GO:0005537 mannose binding; GO:0036094 small molecule binding; ","K12390","CLN5; ceroid-lipofuscinosis neuronal protein 5","hsa04142 Lysosome - Homo sapiens (human); "]
["O75521","Enoyl-CoA delta isomerase 2, mitochondrial OS=Homo sapiens OX=9606 GN=ECI2","ECI2",43.585,38.444,25.6,8,13,8,1.105,1.042,1.068,0.961,0.893,0.95,0.872,0.00854,"mitochondria\r","GO:0034440 lipid oxidation; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0030258 lipid modification; GO:0044248 cellular catabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0009987 cellular process; GO:0006629 lipid metabolic process; GO:0016042 lipid catabolic process; GO:0019395 fatty acid oxidation; GO:0055114 oxidation-reduction process; GO:0044712 single-organism catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006635 fatty acid beta-oxidation; GO:0072329 monocarboxylic acid catabolic process; GO:0044282 small molecule catabolic process; GO:0006631 fatty acid metabolic process; GO:0044238 primary metabolic process; GO:0046395 carboxylic acid catabolic process; GO:1901575 organic substance catabolic process; GO:0044710 single-organism metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0016054 organic acid catabolic process; GO:0044242 cellular lipid catabolic process; GO:0006082 organic acid metabolic process; GO:0009062 fatty acid catabolic process; GO:0009056 catabolic process; GO:0043436 oxoacid metabolic process; ","GO:0016020 membrane; GO:0043229 intracellular organelle; GO:0044439 peroxisomal part; GO:0005777 peroxisome; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044438 microbody part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0031907 microbody lumen; GO:0070013 intracellular organelle lumen; GO:0005782 peroxisomal matrix; GO:0005622 intracellular; GO:0044464 cell part; GO:0042579 microbody; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0016853 isomerase activity; GO:0000062 fatty-acyl-CoA binding; GO:0005102 receptor binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0043168 anion binding; GO:0016860 intramolecular oxidoreductase activity; GO:0004165 dodecenoyl-CoA delta-isomerase activity; GO:1901681 sulfur compound binding; GO:0048037 cofactor binding; GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds; GO:0050662 coenzyme binding; ","K13239","ECI2; Delta3-Delta2-enoyl-CoA isomerase [EC:5.3.3.8]","hsa00071 Fatty acid degradation - Homo sapiens (human); hsa04146 Peroxisome - Homo sapiens (human); ","IPR029045; IPR000582; IPR014352; ","\"ClpP/crotonase-like domain; Acyl-CoA-binding protein, ACBP; FERM/acyl-CoA-binding protein, 3-helical bundle; \"\r"]
["O75531","Barrier-to-autointegration factor OS=Homo sapiens OX=9606 GN=BANF1","BANF1",10.058,4.3298,20.2,3,3,3,1.052,0.963,1.017,0.954,1.072,0.949,0.981,0.696,"extracellular\r","GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0006997 nucleus organization; GO:0010256 endomembrane system organization; GO:0019043 establishment of viral latency; GO:0006725 cellular aromatic compound metabolic process; GO:0006259 DNA metabolic process; GO:0044699 single-organism process; GO:0051169 nuclear transport; GO:0043207 response to external biotic stimulus; GO:0044764 multi-organism cellular process; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:1903047 mitotic cell cycle process; GO:0044237 cellular metabolic process; GO:0009607 response to biotic stimulus; GO:0051234 establishment of localization; GO:0006998 nuclear envelope organization; GO:0071704 organic substance metabolic process; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0046483 heterocycle metabolic process; GO:0051081 nuclear envelope disassembly; GO:0006139 nucleobase-containing compound metabolic process; GO:0016032 viral process; GO:0007084 mitotic nuclear envelope reassembly; GO:0019042 viral latency; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0009987 cellular process; GO:0031468 nuclear envelope reassembly; GO:0015074 DNA integration; GO:0007077 mitotic nuclear envelope disassembly; GO:0000278 mitotic cell cycle; GO:0075713 establishment of integrated proviral latency; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0044802 single-organism membrane organization; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0044238 primary metabolic process; GO:0051704 multi-organism process; GO:0051641 cellular localization; GO:0006810 transport; GO:0030397 membrane disassembly; GO:0090304 nucleic acid metabolic process; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0044260 cellular macromolecule metabolic process; GO:0022411 cellular component disassembly; GO:0022402 cell cycle process; GO:0051179 localization; GO:0009615 response to virus; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0000793 condensed chromosome; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003677 DNA binding; GO:0042802 identical protein binding; GO:0047485 protein N-terminus binding; GO:0097726 LEM domain binding; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0046983 protein dimerization activity; GO:0003676 nucleic acid binding; GO:0008022 protein C-terminus binding; GO:0005515 protein binding; GO:0019904 protein domain specific binding; GO:0019899 enzyme binding; "]
["O75533","Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1","SF3B1",145.83,78.544,11.1,11,15,11,0.927,0.888,0.94,1.056,1.15,1.097,1.199,3.8E-3,"plasma membrane\r","GO:0044085 cellular component biogenesis; GO:0016043 cellular component organization; GO:0022613 ribonucleoprotein complex biogenesis; GO:0022618 ribonucleoprotein complex assembly; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0008152 metabolic process; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0071826 ribonucleoprotein complex subunit organization; GO:0046483 heterocycle metabolic process; GO:0022607 cellular component assembly; GO:0006139 nucleobase-containing compound metabolic process; GO:0009893 positive regulation of metabolic process; GO:0065003 macromolecular complex assembly; GO:0010628 positive regulation of gene expression; GO:0000375 RNA splicing, via transesterification reactions; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0006396 RNA processing; GO:0034622 cellular macromolecular complex assembly; GO:0010468 regulation of gene expression; GO:0045815 positive regulation of gene expression, epigenetic; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0043933 macromolecular complex subunit organization; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:0040029 regulation of gene expression, epigenetic; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0010467 gene expression; GO:0000245 spliceosomal complex assembly; GO:0016071 mRNA metabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0005686 U2 snRNP; GO:0005684 U2-type spliceosomal complex; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0044464 cell part; GO:0005622 intracellular; GO:0071004 U2-type prespliceosome; GO:0043227 membrane-bounded organelle; GO:0005689 U12-type spliceosomal complex; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005681 spliceosomal complex; GO:0034693 U11/U12 snRNP; GO:0097525 spliceosomal snRNP complex; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0071013 catalytic step 2 spliceosome; GO:0071010 prespliceosome; GO:1990904 ribonucleoprotein complex; GO:0030532 small nuclear ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003729 mRNA binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; ","K12828","SF3B1; splicing factor 3B subunit 1","hsa03040 Spliceosome - Homo sapiens (human); ","IPR011989; IPR015016; IPR016024; ","Armadillo-like helical; Splicing factor 3B subunit 1; Armadillo-type fold; \r"]
["O75534","Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1","CSDE1",88.884,53.849,19.7,15,18,15,0.858,0.88,0.892,1.13,1.133,1.146,1.296,2.43e-05,"nucleus\r","GO:0022414 reproductive process; GO:0008584 male gonad development; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0044702 single organism reproductive process; GO:1901361 organic cyclic compound catabolic process; GO:0043170 macromolecule metabolic process; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0003006 developmental process involved in reproduction; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0048608 reproductive structure development; GO:1901360 organic cyclic compound metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0006401 RNA catabolic process; GO:0016070 RNA metabolic process; GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay; GO:1903506 regulation of nucleic acid-templated transcription; GO:0019439 aromatic compound catabolic process; GO:1901575 organic substance catabolic process; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0048856 anatomical structure development; GO:0016071 mRNA metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0000003 reproduction; GO:0044707 single-multicellular organism process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0046661 male sex differentiation; GO:0008406 gonad development; GO:0048519 negative regulation of biological process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0007548 sex differentiation; GO:0044248 cellular catabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0034655 nucleobase-containing compound catabolic process; GO:0061458 reproductive system development; GO:0009987 cellular process; GO:0045137 development of primary sexual characteristics; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0048731 system development; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0044767 single-organism developmental process; GO:0009057 macromolecule catabolic process; GO:0046546 development of primary male sexual characteristics; GO:0009056 catabolic process; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0070937 CRD-mediated mRNA stability complex; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0012505 endomembrane system; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0005740 mitochondrial envelope; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005622 intracellular; GO:0044464 cell part; GO:0031975 envelope; GO:0019866 organelle inner membrane; GO:0043234 protein complex; GO:0005794 Golgi apparatus; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003677 DNA binding; GO:0003723 RNA binding; GO:0005515 protein binding; GO:0005488 binding; GO:0003676 nucleic acid binding; ",{"$nulls":3},"IPR024642; IPR011129; IPR012340; IPR002059; ","\"SUZ-C domain; Cold shock domain; Nucleic acid-binding, OB-fold; Cold-shock protein, DNA-binding; \"\r"]
["O75569","Interferon-inducible double-stranded RNA-dependent protein kinase activator A OS=Homo sapiens OX=9606 GN=PRKRA","PRKRA",34.404,62.435,24.6,6,7,6,1.065,0.919,0.961,1.007,0.952,1.076,1.031,0.613,"cytoplasm\r","GO:0010941 regulation of cell death; GO:0010608 posttranscriptional regulation of gene expression; GO:0042474 middle ear morphogenesis; GO:0044237 cellular metabolic process; GO:0009607 response to biotic stimulus; GO:0008285 negative regulation of cell proliferation; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0048562 embryonic organ morphogenesis; GO:0044093 positive regulation of molecular function; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0044419 interspecies interaction between organisms; GO:0009790 embryo development; GO:0048598 embryonic morphogenesis; GO:0090596 sensory organ morphogenesis; GO:0006396 RNA processing; GO:0051716 cellular response to stimulus; GO:0014070 response to organic cyclic compound; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0034249 negative regulation of cellular amide metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0048513 animal organ development; GO:0043583 ear development; GO:0031047 gene silencing by RNA; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0044260 cellular macromolecule metabolic process; GO:0009887 animal organ morphogenesis; GO:2001244 positive regulation of intrinsic apoptotic signaling pathway; GO:0006464 cellular protein modification process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0043068 positive regulation of programmed cell death; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0016310 phosphorylation; GO:0044707 single-multicellular organism process; GO:0042127 regulation of cell proliferation; GO:0043067 regulation of programmed cell death; GO:0044267 cellular protein metabolic process; GO:0017148 negative regulation of translation; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0009653 anatomical structure morphogenesis; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0071359 cellular response to dsRNA; GO:1902531 regulation of intracellular signal transduction; GO:0006950 response to stress; GO:0048731 system development; GO:0002376 immune system process; GO:0071407 cellular response to organic cyclic compound; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0034248 regulation of cellular amide metabolic process; GO:0048705 skeletal system morphogenesis; GO:0016246 RNA interference; GO:0009890 negative regulation of biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0006955 immune response; GO:0048584 positive regulation of response to stimulus; GO:0043412 macromolecule modification; GO:0007423 sensory organ development; GO:0035195 gene silencing by miRNA; GO:0023051 regulation of signaling; GO:0035194 posttranscriptional gene silencing by RNA; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0006796 phosphate-containing compound metabolic process; GO:2001233 regulation of apoptotic signaling pathway; GO:0010646 regulation of cell communication; GO:0030422 production of siRNA involved in RNA interference; GO:0006979 response to oxidative stress; GO:0034599 cellular response to oxidative stress; GO:0070887 cellular response to chemical stimulus; GO:0031054 pre-miRNA processing; GO:0034470 ncRNA processing; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0043331 response to dsRNA; GO:0048522 positive regulation of cellular process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0010942 positive regulation of cell death; GO:0016070 RNA metabolic process; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0042221 response to chemical; GO:0090304 nucleic acid metabolic process; GO:1901699 cellular response to nitrogen compound; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0070918 production of small RNA involved in gene silencing by RNA; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0009615 response to virus; GO:0001501 skeletal system development; GO:0006725 cellular aromatic compound metabolic process; GO:0048568 embryonic organ development; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0043065 positive regulation of apoptotic process; GO:0043207 response to external biotic stimulus; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0071704 organic substance metabolic process; GO:0006468 protein phosphorylation; GO:0016032 viral process; GO:0023056 positive regulation of signaling; GO:2001235 positive regulation of apoptotic signaling pathway; GO:0034641 cellular nitrogen compound metabolic process; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:0010629 negative regulation of gene expression; GO:0016441 posttranscriptional gene silencing; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0040029 regulation of gene expression, epigenetic; GO:0035196 production of miRNAs involved in gene silencing by miRNA; GO:0016458 gene silencing; GO:0044767 single-organism developmental process; GO:0006417 regulation of translation; GO:0051246 regulation of protein metabolic process; GO:0031050 dsRNA fragmentation; GO:0042473 outer ear morphogenesis; GO:2001242 regulation of intrinsic apoptotic signaling pathway; GO:0042471 ear morphogenesis; GO:0051248 negative regulation of protein metabolic process; GO:0010467 gene expression; GO:0009967 positive regulation of signal transduction; GO:0031327 negative regulation of cellular biosynthetic process; GO:0034660 ncRNA metabolic process; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0048471 perinuclear region of cytoplasm; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0042802 identical protein binding; GO:0030234 enzyme regulator activity; GO:0042803 protein homodimerization activity; GO:0003725 double-stranded RNA binding; GO:0005488 binding; GO:0046983 protein dimerization activity; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0019899 enzyme binding; GO:0008047 enzyme activator activity; ",{"$nulls":3},"IPR014720; IPR032478; ","\"Double-stranded RNA-binding domain; Staufen, C-terminal; \"\r"]
["O75592","E3 ubiquitin-protein ligase MYCBP2 OS=Homo sapiens OX=9606 GN=MYCBP2","MYCBP2",510.08,13.996,1.3,5,6,5,0.933,1,0.949,1.022,1.036,1.092,1.093,0.0376,"nucleus\r","GO:0050794 regulation of cellular process; GO:0006725 cellular aromatic compound metabolic process; GO:0097659 nucleic acid-templated transcription; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0006355 regulation of transcription, DNA-templated; GO:0031326 regulation of cellular biosynthetic process; GO:0016567 protein ubiquitination; GO:0080090 regulation of primary metabolic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0031323 regulation of cellular metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0034645 cellular macromolecule biosynthetic process; GO:0090304 nucleic acid metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0032446 protein modification by small protein conjugation; GO:0006351 transcription, DNA-templated; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0010467 gene expression; GO:0006464 cellular protein modification process; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0065007 biological regulation; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; ","GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0008270 zinc ion binding; GO:0016740 transferase activity; ","K10693",null,null,"IPR003646; IPR009091; IPR004939; IPR001841; IPR013783; IPR013083; IPR014756; IPR008979; IPR012983; ","\"SH3-like domain, bacterial-type; Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II; APC10/DOC domain; Zinc finger, RING-type; Immunoglobulin-like fold; Zinc finger, RING/FYVE/PHD-type; Immunoglobulin E-set; Galactose-binding domain-like; PHR; \"\r"]
["O75608","Acyl-protein thioesterase 1 OS=Homo sapiens OX=9606 GN=LYPLA1","LYPLA1",24.669,39.641,34.3,6,10,6,0.9,0.869,1.049,1.059,1.075,1.041,1.127,0.104,"cytoplasm\r","GO:0060627 regulation of vesicle-mediated transport; GO:0090005 negative regulation of establishment of protein localization to plasma membrane; GO:0051129 negative regulation of cellular component organization; GO:0044699 single-organism process; GO:0098734 macromolecule depalmitoylation; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0042157 lipoprotein metabolic process; GO:1903729 regulation of plasma membrane organization; GO:0008152 metabolic process; GO:1904375 regulation of protein localization to cell periphery; GO:0032879 regulation of localization; GO:0032787 monocarboxylic acid metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0042159 lipoprotein catabolic process; GO:0098732 macromolecule deacylation; GO:0006629 lipid metabolic process; GO:0051051 negative regulation of transport; GO:1905476 negative regulation of protein localization to membrane; GO:1903828 negative regulation of cellular protein localization; GO:0002084 protein depalmitoylation; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0051341 regulation of oxidoreductase activity; GO:1901575 organic substance catabolic process; GO:0050789 regulation of biological process; GO:0035601 protein deacylation; GO:0032768 regulation of monooxygenase activity; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0030163 protein catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0006464 cellular protein modification process; GO:0042996 regulation of Golgi to plasma membrane protein transport; GO:0051223 regulation of protein transport; GO:0006082 organic acid metabolic process; GO:0036211 protein modification process; GO:0050999 regulation of nitric-oxide synthase activity; GO:0043436 oxoacid metabolic process; GO:0050794 regulation of cellular process; GO:1903076 regulation of protein localization to plasma membrane; GO:0044267 cellular protein metabolic process; GO:1904376 negative regulation of protein localization to cell periphery; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0070201 regulation of establishment of protein localization; GO:0060341 regulation of cellular localization; GO:0071704 organic substance metabolic process; GO:1903077 negative regulation of protein localization to plasma membrane; GO:1905475 regulation of protein localization to membrane; GO:0032880 regulation of protein localization; GO:0090003 regulation of establishment of protein localization to plasma membrane; GO:0009987 cellular process; GO:0051224 negative regulation of protein transport; GO:0051049 regulation of transport; GO:0006631 fatty acid metabolic process; GO:0044238 primary metabolic process; GO:0042997 negative regulation of Golgi to plasma membrane protein transport; GO:0009057 macromolecule catabolic process; GO:0019752 carboxylic acid metabolic process; GO:1904950 negative regulation of establishment of protein localization; GO:0051128 regulation of cellular component organization; GO:0043412 macromolecule modification; GO:0009056 catabolic process; GO:1903827 regulation of cellular protein localization; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0098599 palmitoyl hydrolase activity; GO:0052689 carboxylic ester hydrolase activity; GO:0003824 catalytic activity; GO:0016788 hydrolase activity, acting on ester bonds; GO:0004620 phospholipase activity; GO:0004622 lysophospholipase activity; GO:0016787 hydrolase activity; GO:0008474 palmitoyl-(protein) hydrolase activity; GO:0016790 thiolester hydrolase activity; GO:0016298 lipase activity; ","K06128","LYPLA1; lysophospholipase I [EC:3.1.1.5]","hsa05231 Choline metabolism in cancer - Homo sapiens (human); hsa00564 Glycerophospholipid metabolism - Homo sapiens (human); ","IPR029058; IPR003140; ","Alpha/Beta hydrolase fold; Phospholipase/carboxylesterase/thioesterase; \r"]
["O75635","Serpin B7 OS=Homo sapiens OX=9606 GN=SERPINB7","SERPINB7",42.904,45.042,31.3,10,12,10,0.885,0.921,0.859,1.077,1.12,1.111,1.241,0.000763,"cytoplasm\r","GO:0072124 regulation of glomerular mesangial cell proliferation; GO:0044246 regulation of multicellular organismal metabolic process; GO:0009891 positive regulation of biosynthetic process; GO:0032914 positive regulation of transforming growth factor beta1 production; GO:0010466 negative regulation of peptidase activity; GO:0009893 positive regulation of metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:1901722 regulation of cell proliferation involved in kidney development; GO:1904018 positive regulation of vasculature development; GO:0052548 regulation of endopeptidase activity; GO:0090192 regulation of glomerulus development; GO:0090193 positive regulation of glomerulus development; GO:0080090 regulation of primary metabolic process; GO:0048522 positive regulation of cellular process; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0051336 regulation of hydrolase activity; GO:0010714 positive regulation of collagen metabolic process; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0032908 regulation of transforming growth factor beta1 production; GO:0010604 positive regulation of macromolecule metabolic process; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0052547 regulation of peptidase activity; GO:0051094 positive regulation of developmental process; GO:2000026 regulation of multicellular organismal development; GO:0050794 regulation of cellular process; GO:0090184 positive regulation of kidney development; GO:0010951 negative regulation of endopeptidase activity; GO:0042127 regulation of cell proliferation; GO:0060255 regulation of macromolecule metabolic process; GO:0032967 positive regulation of collagen biosynthetic process; GO:0001819 positive regulation of cytokine production; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0051346 negative regulation of hydrolase activity; GO:0051239 regulation of multicellular organismal process; GO:0009889 regulation of biosynthetic process; GO:0072126 positive regulation of glomerular mesangial cell proliferation; GO:0044253 positive regulation of multicellular organismal metabolic process; GO:0090361 regulation of platelet-derived growth factor production; GO:0090362 positive regulation of platelet-derived growth factor production; GO:0045861 negative regulation of proteolysis; GO:0071634 regulation of transforming growth factor beta production; GO:1901724 positive regulation of cell proliferation involved in kidney development; GO:1901342 regulation of vasculature development; GO:0010556 regulation of macromolecule biosynthetic process; GO:0030162 regulation of proteolysis; GO:0048518 positive regulation of biological process; GO:0009892 negative regulation of metabolic process; GO:0032965 regulation of collagen biosynthetic process; GO:0051246 regulation of protein metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0001817 regulation of cytokine production; GO:0090183 regulation of kidney development; GO:0071636 positive regulation of transforming growth factor beta production; GO:0010712 regulation of collagen metabolic process; GO:0050793 regulation of developmental process; GO:0065007 biological regulation; GO:0008284 positive regulation of cell proliferation; ","GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; ","GO:0004867 serine-type endopeptidase inhibitor activity; GO:0030234 enzyme regulator activity; GO:0030414 peptidase inhibitor activity; GO:0061134 peptidase regulator activity; GO:0061135 endopeptidase regulator activity; GO:0098772 molecular function regulator; GO:0004857 enzyme inhibitor activity; GO:0004866 endopeptidase inhibitor activity; ","K13964",null,null,"IPR023796; ","Serpin domain; \r"]
["O75643","U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200","SNRNP200",244.5,94.596,10.5,23,28,23,0.93,0.914,0.973,1.053,1.036,1.061,1.118,0.00492,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0016043 cellular component organization; GO:0001649 osteoblast differentiation; GO:0044707 single-multicellular organism process; GO:0022613 ribonucleoprotein complex biogenesis; GO:0022618 ribonucleoprotein complex assembly; GO:0006725 cellular aromatic compound metabolic process; GO:0045292 mRNA cis splicing, via spliceosome; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0030154 cell differentiation; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0071826 ribonucleoprotein complex subunit organization; GO:0046483 heterocycle metabolic process; GO:0022607 cellular component assembly; GO:0006139 nucleobase-containing compound metabolic process; GO:0065003 macromolecular complex assembly; GO:0000375 RNA splicing, via transesterification reactions; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0006396 RNA processing; GO:0032502 developmental process; GO:0034622 cellular macromolecular complex assembly; GO:0000354 cis assembly of pre-catalytic spliceosome; GO:0001503 ossification; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0044238 primary metabolic process; GO:0032501 multicellular organismal process; GO:0043933 macromolecular complex subunit organization; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:0090304 nucleic acid metabolic process; GO:0044767 single-organism developmental process; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0000245 spliceosomal complex assembly; GO:0016071 mRNA metabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005681 spliceosomal complex; GO:0005623 cell; GO:0044422 organelle part; GO:0097525 spliceosomal snRNP complex; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0071013 catalytic step 2 spliceosome; GO:1990904 ribonucleoprotein complex; GO:0030532 small nuclear ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0030529 intracellular ribonucleoprotein complex; GO:0005682 U5 snRNP; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0008026 ATP-dependent helicase activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0016887 ATPase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0042802 identical protein binding; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0004004 ATP-dependent RNA helicase activity; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003723 RNA binding; GO:0005524 ATP binding; GO:0070035 purine NTP-dependent helicase activity; GO:0004386 helicase activity; GO:0008186 RNA-dependent ATPase activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003724 RNA helicase activity; GO:0003676 nucleic acid binding; GO:0042623 ATPase activity, coupled; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; ","K12854","SNRNP200; pre-mRNA-splicing helicase BRR2 [EC:3.6.4.13]","hsa03040 Spliceosome - Homo sapiens (human); ","IPR011991; IPR011545; IPR004179; IPR014756; IPR027417; IPR014001; IPR001650; IPR000008; ","\"Winged helix-turn-helix DNA-binding domain; DEAD/DEAH box helicase domain; Sec63 domain; Immunoglobulin E-set; P-loop containing nucleoside triphosphate hydrolase; Helicase superfamily 1/2, ATP-binding domain; Helicase, C-terminal; C2 domain; \"\r"]
["O75663","TIP41-like protein OS=Homo sapiens OX=9606 GN=TIPRL","TIPRL",31.444,17.772,15.8,4,5,4,0.95,0.949,1.009,1.029,1.037,1.075,1.08,0.0336,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0045786 negative regulation of cell cycle; GO:0032515 negative regulation of phosphoprotein phosphatase activity; GO:0043666 regulation of phosphoprotein phosphatase activity; GO:0060255 regulation of macromolecule metabolic process; GO:0031399 regulation of protein modification process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0010923 negative regulation of phosphatase activity; GO:0051346 negative regulation of hydrolase activity; GO:0031400 negative regulation of protein modification process; GO:0000077 DNA damage checkpoint; GO:0000075 cell cycle checkpoint; GO:0035308 negative regulation of protein dephosphorylation; GO:0035303 regulation of dephosphorylation; GO:0051726 regulation of cell cycle; GO:0009987 cellular process; GO:0051716 cellular response to stimulus; GO:0035305 negative regulation of dephosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0006950 response to stress; GO:0010921 regulation of phosphatase activity; GO:0080090 regulation of primary metabolic process; GO:0031570 DNA integrity checkpoint; GO:0031323 regulation of cellular metabolic process; GO:0043086 negative regulation of catalytic activity; GO:0010605 negative regulation of macromolecule metabolic process; GO:0009892 negative regulation of metabolic process; GO:0006974 cellular response to DNA damage stimulus; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0051246 regulation of protein metabolic process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0035304 regulation of protein dephosphorylation; GO:0010563 negative regulation of phosphorus metabolic process; GO:0019222 regulation of metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0045936 negative regulation of phosphate metabolic process; GO:0065007 biological regulation; ","GO:0044424 intracellular part; GO:0005623 cell; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; ","GO:0005515 protein binding; GO:0005488 binding; ","K17607"]
["O75688","Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B","PPM1B",52.642,23.63,9.6,3,3,3,0.915,1.157,1.265,0.758,0.94,0.976,0.801,0.155,"cytoplasm\r","GO:0009968 negative regulation of signal transduction; GO:1903533 regulation of protein targeting; GO:0023051 regulation of signaling; GO:0090317 negative regulation of intracellular protein transport; GO:0002698 negative regulation of immune effector process; GO:0051241 negative regulation of multicellular organismal process; GO:0009058 biosynthetic process; GO:0001818 negative regulation of cytokine production; GO:0031347 regulation of defense response; GO:0044237 cellular metabolic process; GO:0042157 lipoprotein metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0042308 negative regulation of protein import into nucleus; GO:0042306 regulation of protein import into nucleus; GO:0008152 metabolic process; GO:0006499 N-terminal protein myristoylation; GO:0010646 regulation of cell communication; GO:0032879 regulation of localization; GO:0043543 protein acylation; GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling; GO:0032102 negative regulation of response to external stimulus; GO:0032387 negative regulation of intracellular transport; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:1900181 negative regulation of protein localization to nucleus; GO:0042158 lipoprotein biosynthetic process; GO:0002697 regulation of immune effector process; GO:0046823 negative regulation of nucleocytoplasmic transport; GO:0018377 protein myristoylation; GO:0051051 negative regulation of transport; GO:0048525 negative regulation of viral process; GO:1903828 negative regulation of cellular protein localization; GO:0002832 negative regulation of response to biotic stimulus; GO:0042992 negative regulation of transcription factor import into nucleus; GO:0042345 regulation of NF-kappaB import into nucleus; GO:0050687 negative regulation of defense response to virus; GO:0032386 regulation of intracellular transport; GO:0002683 negative regulation of immune system process; GO:0050789 regulation of biological process; GO:1902532 negative regulation of intracellular signal transduction; GO:0048583 regulation of response to stimulus; GO:1900180 regulation of protein localization to nucleus; GO:0044260 cellular macromolecule metabolic process; GO:0051223 regulation of protein transport; GO:0042347 negative regulation of NF-kappaB import into nucleus; GO:0006497 protein lipidation; GO:0006464 cellular protein modification process; GO:0002682 regulation of immune system process; GO:0036211 protein modification process; GO:0050794 regulation of cellular process; GO:0032479 regulation of type I interferon production; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0002831 regulation of response to biotic stimulus; GO:0044267 cellular protein metabolic process; GO:1904589 regulation of protein import; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:0048519 negative regulation of biological process; GO:1904590 negative regulation of protein import; GO:0051239 regulation of multicellular organismal process; GO:0070201 regulation of establishment of protein localization; GO:0042990 regulation of transcription factor import into nucleus; GO:0060341 regulation of cellular localization; GO:0071704 organic substance metabolic process; GO:0050688 regulation of defense response to virus; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0032880 regulation of protein localization; GO:0009059 macromolecule biosynthetic process; GO:0033157 regulation of intracellular protein transport; GO:0009987 cellular process; GO:0009966 regulation of signal transduction; GO:0031348 negative regulation of defense response; GO:1902531 regulation of intracellular signal transduction; GO:0032648 regulation of interferon-beta production; GO:0051224 negative regulation of protein transport; GO:0051049 regulation of transport; GO:0043900 regulation of multi-organism process; GO:0050792 regulation of viral process; GO:0035970 peptidyl-threonine dephosphorylation; GO:0032101 regulation of response to external stimulus; GO:0048585 negative regulation of response to stimulus; GO:0006470 protein dephosphorylation; GO:0044238 primary metabolic process; GO:0006498 N-terminal protein lipidation; GO:0016311 dephosphorylation; GO:1901576 organic substance biosynthetic process; GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling; GO:0044249 cellular biosynthetic process; GO:0043901 negative regulation of multi-organism process; GO:0046822 regulation of nucleocytoplasmic transport; GO:0034645 cellular macromolecule biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0031365 N-terminal protein amino acid modification; GO:0001817 regulation of cytokine production; GO:1904950 negative regulation of establishment of protein localization; GO:0043412 macromolecule modification; GO:0032480 negative regulation of type I interferon production; GO:0032688 negative regulation of interferon-beta production; GO:1903827 regulation of cellular protein localization; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0000287 magnesium ion binding; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0042578 phosphoric ester hydrolase activity; GO:0004722 protein serine/threonine phosphatase activity; GO:0016791 phosphatase activity; GO:0005488 binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0043167 ion binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0004721 phosphoprotein phosphatase activity; GO:0030145 manganese ion binding; ","K04461","PPM1B; protein phosphatase 1B [EC:3.1.3.16]","hsa04010 MAPK signaling pathway - Homo sapiens (human); ","IPR001932; IPR012911; ","\"PPM-type phosphatase domain; Protein serine/threonine phosphatase 2C, C-terminal; \"\r"]
["O75694","Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155","NUP155",155.2,25.978,5.9,7,10,7,1.009,0.926,0.991,1.016,0.969,1.052,1.038,0.35,"cytoplasm\r","GO:0044700 single organism signaling; GO:0050658 RNA transport; GO:0065008 regulation of biological quality; GO:0051169 nuclear transport; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:1902583 multi-organism intracellular transport; GO:0061337 cardiac conduction; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0032879 regulation of localization; GO:0015931 nucleobase-containing compound transport; GO:0044057 regulation of system process; GO:0033365 protein localization to organelle; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0006606 protein import into nucleus; GO:0075733 intracellular transport of virus; GO:0044419 interspecies interaction between organisms; GO:0008104 protein localization; GO:0044765 single-organism transport; GO:0051031 tRNA transport; GO:0007077 mitotic nuclear envelope disassembly; GO:0000278 mitotic cell cycle; GO:0018130 heterocycle biosynthetic process; GO:0072657 protein localization to membrane; GO:0044763 single-organism cellular process; GO:0006941 striated muscle contraction; GO:0032774 RNA biosynthetic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032501 multicellular organismal process; GO:0006611 protein export from nucleus; GO:0051704 multi-organism process; GO:0006810 transport; GO:0007267 cell-cell signaling; GO:0080135 regulation of cellular response to stress; GO:0031047 gene silencing by RNA; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0006913 nucleocytoplasmic transport; GO:0003015 heart process; GO:0086014 atrial cardiac muscle cell action potential; GO:0003013 circulatory system process; GO:1901362 organic cyclic compound biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0046907 intracellular transport; GO:0016925 protein sumoylation; GO:0086066 atrial cardiac muscle cell to AV node cell communication; GO:1902593 single-organism nuclear import; GO:0051028 mRNA transport; GO:0044267 cellular protein metabolic process; GO:0080134 regulation of response to stress; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0051239 regulation of multicellular organismal process; GO:0051236 establishment of RNA localization; GO:0046483 heterocycle metabolic process; GO:0086003 cardiac muscle cell contraction; GO:1902578 single-organism localization; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0051081 nuclear envelope disassembly; GO:0044744 protein targeting to nucleus; GO:1902580 single-organism cellular localization; GO:0034613 cellular protein localization; GO:0090150 establishment of protein localization to membrane; GO:0046794 transport of virus; GO:0006403 RNA localization; GO:0006405 RNA export from nucleus; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0044766 multi-organism transport; GO:0045184 establishment of protein localization; GO:0006409 tRNA export from nucleus; GO:0051276 chromosome organization; GO:0032446 protein modification by small protein conjugation; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0061024 membrane organization; GO:0036228 protein targeting to nuclear inner membrane; GO:0006928 movement of cell or subcellular component; GO:0043412 macromolecule modification; GO:0051179 localization; GO:0030048 actin filament-based movement; GO:0010256 endomembrane system organization; GO:0003012 muscle system process; GO:0070252 actin-mediated cell contraction; GO:0072594 establishment of protein localization to organelle; GO:0017038 protein import; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:1902581 multi-organism cellular localization; GO:0051168 nuclear export; GO:0044764 multi-organism cellular process; GO:0051234 establishment of localization; GO:0071431 tRNA-containing ribonucleoprotein complex export from nucleus; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0071427 mRNA-containing ribonucleoprotein complex export from nucleus; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0050657 nucleic acid transport; GO:0001508 action potential; GO:0010827 regulation of glucose transport; GO:0033036 macromolecule localization; GO:0010468 regulation of gene expression; GO:0086026 atrial cardiac muscle cell to AV node cell signaling; GO:0035637 multicellular organismal signaling; GO:1901360 organic cyclic compound metabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0071166 ribonucleoprotein complex localization; GO:1902582 single-organism intracellular transport; GO:0042391 regulation of membrane potential; GO:0016070 RNA metabolic process; GO:0086001 cardiac muscle cell action potential; GO:0030397 membrane disassembly; GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0019222 regulation of metabolic process; GO:1900034 regulation of cellular response to heat; GO:0019083 viral transcription; GO:0036211 protein modification process; GO:1902579 multi-organism localization; GO:0016043 cellular component organization; GO:0006997 nucleus organization; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:1903522 regulation of blood circulation; GO:0008016 regulation of heart contraction; GO:0060048 cardiac muscle contraction; GO:0071704 organic substance metabolic process; GO:0006998 nuclear envelope organization; GO:0018205 peptidyl-lysine modification; GO:0006936 muscle contraction; GO:0016032 viral process; GO:0019080 viral gene expression; GO:0006886 intracellular protein transport; GO:0008015 blood circulation; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0060047 heart contraction; GO:0009987 cellular process; GO:0006406 mRNA export from nucleus; GO:0003008 system process; GO:0010629 negative regulation of gene expression; GO:0051049 regulation of transport; GO:0006807 nitrogen compound metabolic process; GO:0044802 single-organism membrane organization; GO:0044249 cellular biosynthetic process; GO:0086019 cell-cell signaling involved in cardiac conduction; GO:0051641 cellular localization; GO:0018193 peptidyl-amino acid modification; GO:0070727 cellular macromolecule localization; GO:0016458 gene silencing; GO:0051170 nuclear import; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0071426 ribonucleoprotein complex export from nucleus; GO:0086002 cardiac muscle cell action potential involved in contraction; GO:0022411 cellular component disassembly; GO:0010467 gene expression; GO:0022402 cell cycle process; GO:0034504 protein localization to nucleus; GO:0071705 nitrogen compound transport; GO:0007049 cell cycle; GO:0090435 protein localization to nuclear envelope; GO:0086065 cell communication involved in cardiac conduction; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005643 nuclear pore; GO:0031090 organelle membrane; GO:0044611 nuclear pore inner ring; GO:0005635 nuclear envelope; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0032991 macromolecular complex; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031965 nuclear membrane; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0031975 envelope; GO:0043227 membrane-bounded organelle; GO:0043234 protein complex; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0017056 structural constituent of nuclear pore; GO:0005198 structural molecule activity; GO:0005488 binding; GO:0005215 transporter activity; ","K14312","NUP155; nuclear pore complex protein Nup155","hsa03013 RNA transport - Homo sapiens (human); ","IPR014908; IPR007187; ","\"Nucleoporin, Nup133/Nup155-like, N-terminal; Nucleoporin, Nup133/Nup155-like, C-terminal; \"\r"]
["O75695","Protein XRP2 OS=Homo sapiens OX=9606 GN=RP2","RP2",39.641,10.355,11.1,4,6,4,0.942,1.019,0.929,1.038,1.064,0.985,1.068,0.145,"cyto_nucl\r","GO:0016043 cellular component organization; GO:0007601 visual perception; GO:0048869 cellular developmental process; GO:0048193 Golgi vesicle transport; GO:0032989 cellular component morphogenesis; GO:0044699 single-organism process; GO:0015031 protein transport; GO:0050877 neurological system process; GO:0051234 establishment of localization; GO:0006457 protein folding; GO:0009653 anatomical structure morphogenesis; GO:0051345 positive regulation of hydrolase activity; GO:0044093 positive regulation of molecular function; GO:0007010 cytoskeleton organization; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0009987 cellular process; GO:0032502 developmental process; GO:0007600 sensory perception; GO:0003008 system process; GO:0043547 positive regulation of GTPase activity; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0071702 organic substance transport; GO:0050953 sensory perception of light stimulus; GO:0032501 multicellular organismal process; GO:0043085 positive regulation of catalytic activity; GO:0006810 transport; GO:0045184 establishment of protein localization; GO:0000902 cell morphogenesis; GO:0051336 regulation of hydrolase activity; GO:0006996 organelle organization; GO:0050790 regulation of catalytic activity; GO:0044767 single-organism developmental process; GO:0065009 regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0006892 post-Golgi vesicle-mediated transport; GO:0051179 localization; GO:0048856 anatomical structure development; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0044450 microtubule organizing center part; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:1990075 periciliary membrane compartment; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0005654 nucleoplasm; GO:0005815 microtubule organizing center; GO:0070013 intracellular organelle lumen; GO:0098590 plasma membrane region; GO:0015630 microtubule cytoskeleton; GO:0044441 ciliary part; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0005929 cilium; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0036064 ciliary basal body; GO:0044463 cell projection part; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0005813 centrosome; GO:0005814 centriole; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0030695 GTPase regulator activity; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0098772 molecular function regulator; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0008092 cytoskeletal protein binding; GO:0030234 enzyme regulator activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0003779 actin binding; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0051082 unfolded protein binding; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0008047 enzyme activator activity; GO:0005096 GTPase activator activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0036094 small molecule binding; ","K18272",null,null,"IPR006599; IPR016098; IPR017901; IPR013912; IPR012945; ","\"CARP motif; Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal; C-CAP/cofactor C-like domain; Adenylate cyclase-associated CAP, C-terminal; Tubulin binding cofactor C-like domain; \"\r"]
["O75718","Cartilage-associated protein OS=Homo sapiens OX=9606 GN=CRTAP","CRTAP",46.561,7.3114,7.2,3,3,3,1.205,1.167,1.148,0.814,0.817,0.879,0.713,2.99E-4,"extracellular\r","GO:0065008 regulation of biological quality; GO:0018400 peptidyl-proline hydroxylation to 3-hydroxy-L-proline; GO:0022414 reproductive process; GO:0061077 chaperone-mediated protein folding; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0031400 negative regulation of protein modification process; GO:0006457 protein folding; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:1901874 negative regulation of post-translational protein modification; GO:0044702 single organism reproductive process; GO:1901873 regulation of post-translational protein modification; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0080090 regulation of primary metabolic process; GO:0044281 small molecule metabolic process; GO:0019953 sexual reproduction; GO:0044763 single-organism cellular process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051704 multi-organism process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006464 cellular protein modification process; GO:0006082 organic acid metabolic process; GO:0036211 protein modification process; GO:0048609 multicellular organismal reproductive process; GO:0043436 oxoacid metabolic process; GO:0050794 regulation of cellular process; GO:0000003 reproduction; GO:0060255 regulation of macromolecule metabolic process; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0006575 cellular modified amino acid metabolic process; GO:0009987 cellular process; GO:0018126 protein hydroxylation; GO:0019511 peptidyl-proline hydroxylation; GO:0048232 male gamete generation; GO:0007283 spermatogenesis; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:1901605 alpha-amino acid metabolic process; GO:0018208 peptidyl-proline modification; GO:0009892 negative regulation of metabolic process; GO:0007276 gamete generation; GO:0018193 peptidyl-amino acid modification; GO:0032504 multicellular organism reproduction; GO:0051246 regulation of protein metabolic process; GO:0044703 multi-organism reproductive process; GO:0019752 carboxylic acid metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0031647 regulation of protein stability; GO:0043412 macromolecule modification; GO:0050821 protein stabilization; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0005788 endoplasmic reticulum lumen; GO:0043229 intracellular organelle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0031012 extracellular matrix; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044432 endoplasmic reticulum part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005578 proteinaceous extracellular matrix; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0005515 protein binding; GO:0005488 binding; GO:0032403 protein complex binding; GO:0044877 macromolecular complex binding; ","K19606",null,null,"IPR011990; ","Tetratricopeptide-like helical domain; \r"]
["O75746","Calcium-binding mitochondrial carrier protein Aralar1 OS=Homo sapiens OX=9606 GN=SLC25A12","SLC25A12",74.761,54.537,16.8,11,17,8,1.097,1.017,1.098,0.971,0.99,0.947,0.905,0.0254,"cytoplasm\r","GO:0016051 carbohydrate biosynthetic process; GO:0034220 ion transmembrane transport; GO:0019319 hexose biosynthetic process; GO:0006839 mitochondrial transport; GO:0015807 L-amino acid transport; GO:0044699 single-organism process; GO:0046364 monosaccharide biosynthetic process; GO:0009058 biosynthetic process; GO:0070778 L-aspartate transport; GO:0022904 respiratory electron transport chain; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0098656 anion transmembrane transport; GO:0071704 organic substance metabolic process; GO:0051234 establishment of localization; GO:0006006 glucose metabolic process; GO:1902475 L-alpha-amino acid transmembrane transport; GO:0008152 metabolic process; GO:0006094 gluconeogenesis; GO:1902578 single-organism localization; GO:0006091 generation of precursor metabolites and energy; GO:1903825 organic acid transmembrane transport; GO:0005996 monosaccharide metabolic process; GO:0051592 response to calcium ion; GO:0006865 amino acid transport; GO:0010035 response to inorganic substance; GO:0009987 cellular process; GO:1905039 carboxylic acid transmembrane transport; GO:0044765 single-organism transport; GO:0044711 single-organism biosynthetic process; GO:0043490 malate-aspartate shuttle; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0015810 aspartate transport; GO:0089712 L-aspartate transmembrane transport; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0005975 carbohydrate metabolic process; GO:0015813 L-glutamate transport; GO:0003333 amino acid transmembrane transport; GO:0046942 carboxylic acid transport; GO:1901576 organic substance biosynthetic process; GO:0045333 cellular respiration; GO:0015849 organic acid transport; GO:0010038 response to metal ion; GO:0015800 acidic amino acid transport; GO:0006810 transport; GO:0006820 anion transport; GO:0044723 single-organism carbohydrate metabolic process; GO:0089711 L-glutamate transmembrane transport; GO:0055085 transmembrane transport; GO:0015711 organic anion transport; GO:0042221 response to chemical; GO:0015740 C4-dicarboxylate transport; GO:0044710 single-organism metabolic process; GO:0006811 ion transport; GO:0015980 energy derivation by oxidation of organic compounds; GO:0044283 small molecule biosynthetic process; GO:0022900 electron transport chain; GO:0006835 dicarboxylic acid transport; GO:0051179 localization; GO:0071705 nitrogen compound transport; GO:0019318 hexose metabolic process; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044429 mitochondrial part; GO:0031090 organelle membrane; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0005740 mitochondrial envelope; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0043209 myelin sheath; GO:0031975 envelope; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0005310 dicarboxylic acid transmembrane transporter activity; GO:0005342 organic acid transmembrane transporter activity; GO:0015179 L-amino acid transmembrane transporter activity; GO:0015075 ion transmembrane transporter activity; GO:0043167 ion binding; GO:0015556 C4-dicarboxylate transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0015172 acidic amino acid transmembrane transporter activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0005313 L-glutamate transmembrane transporter activity; GO:0015183 L-aspartate transmembrane transporter activity; GO:0005488 binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005509 calcium ion binding; GO:0008514 organic anion transmembrane transporter activity; GO:0005215 transporter activity; GO:0008509 anion transmembrane transporter activity; GO:0022857 transmembrane transporter activity; GO:0046943 carboxylic acid transmembrane transporter activity; GO:0015171 amino acid transmembrane transporter activity; ","K15105",null,null,"IPR023395; IPR002048; IPR011992; ","Mitochondrial carrier domain; EF-hand domain; EF-hand domain pair; \r"]
["O75781","Paralemmin-1 OS=Homo sapiens OX=9606 GN=PALM","PALM",42.075,84.43,34.9,13,15,12,1.211,1.123,1.167,0.839,0.837,0.844,0.72,0.00442,"nucleus\r","GO:0021700 developmental maturation; GO:0065008 regulation of biological quality; GO:0030815 negative regulation of cAMP metabolic process; GO:0060491 regulation of cell projection assembly; GO:0045980 negative regulation of nucleotide metabolic process; GO:0090002 establishment of protein localization to plasma membrane; GO:0015031 protein transport; GO:0008360 regulation of cell shape; GO:0008104 protein localization; GO:0044765 single-organism transport; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0051174 regulation of phosphorus metabolic process; GO:0071214 cellular response to abiotic stimulus; GO:0072657 protein localization to membrane; GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway; GO:0080090 regulation of primary metabolic process; GO:0031346 positive regulation of cell projection organization; GO:0044763 single-organism cellular process; GO:0007009 plasma membrane organization; GO:0031323 regulation of cellular metabolic process; GO:0043086 negative regulation of catalytic activity; GO:0032501 multicellular organismal process; GO:0051339 regulation of lyase activity; GO:0006810 transport; GO:0031279 regulation of cyclase activity; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0030809 negative regulation of nucleotide biosynthetic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0006140 regulation of nucleotide metabolic process; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0044707 single-multicellular organism process; GO:0072661 protein targeting to plasma membrane; GO:0009628 response to abiotic stimulus; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:1990778 protein localization to cell periphery; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0045761 regulation of adenylate cyclase activity; GO:1902578 single-organism localization; GO:0009889 regulation of biosynthetic process; GO:0030817 regulation of cAMP biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902580 single-organism cellular localization; GO:0007275 multicellular organism development; GO:0034613 cellular protein localization; GO:0007010 cytoskeleton organization; GO:0009966 regulation of signal transduction; GO:0090150 establishment of protein localization to membrane; GO:0031280 negative regulation of cyclase activity; GO:0060074 synapse maturation; GO:0048731 system development; GO:0051350 negative regulation of lyase activity; GO:0051602 response to electrical stimulus; GO:0071702 organic substance transport; GO:0007194 negative regulation of adenylate cyclase activity; GO:0060160 negative regulation of dopamine receptor signaling pathway; GO:0009892 negative regulation of metabolic process; GO:0030799 regulation of cyclic nucleotide metabolic process; GO:0050808 synapse organization; GO:0045184 establishment of protein localization; GO:0051491 positive regulation of filopodium assembly; GO:0009890 negative regulation of biosynthetic process; GO:0072659 protein localization to plasma membrane; GO:0006996 organelle organization; GO:1900543 negative regulation of purine nucleotide metabolic process; GO:0061024 membrane organization; GO:0006928 movement of cell or subcellular component; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0045936 negative regulation of phosphate metabolic process; GO:0010256 endomembrane system organization; GO:1900372 negative regulation of purine nucleotide biosynthetic process; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0051130 positive regulation of cellular component organization; GO:0006612 protein targeting to membrane; GO:0071257 cellular response to electrical stimulus; GO:0051649 establishment of localization in cell; GO:0010646 regulation of cell communication; GO:0030814 regulation of cAMP metabolic process; GO:0033036 macromolecule localization; GO:0030808 regulation of nucleotide biosynthetic process; GO:0032502 developmental process; GO:0030802 regulation of cyclic nucleotide biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0008277 regulation of G-protein coupled receptor protein signaling pathway; GO:0048522 positive regulation of cellular process; GO:1902582 single-organism intracellular transport; GO:0060159 regulation of dopamine receptor signaling pathway; GO:0050789 regulation of biological process; GO:1900371 regulation of purine nucleotide biosynthetic process; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0048856 anatomical structure development; GO:0016043 cellular component organization; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044087 regulation of cellular component biogenesis; GO:0031344 regulation of cell projection organization; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0030803 negative regulation of cyclic nucleotide biosynthetic process; GO:0051489 regulation of filopodium assembly; GO:0006886 intracellular protein transport; GO:0009987 cellular process; GO:0044802 single-organism membrane organization; GO:0030800 negative regulation of cyclic nucleotide metabolic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0048585 negative regulation of response to stimulus; GO:0048518 positive regulation of biological process; GO:0030818 negative regulation of cAMP biosynthetic process; GO:0051641 cellular localization; GO:1900542 regulation of purine nucleotide metabolic process; GO:0070727 cellular macromolecule localization; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0010563 negative regulation of phosphorus metabolic process; GO:0051128 regulation of cellular component organization; GO:0031327 negative regulation of cellular biosynthetic process; GO:0022604 regulation of cell morphogenesis; GO:0044089 positive regulation of cellular component biogenesis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016323 basolateral plasma membrane; GO:0016020 membrane; GO:0030425 dendrite; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0098858 actin-based cell projection; GO:0005623 cell; GO:0032279 asymmetric synapse; GO:0043197 dendritic spine; GO:0032589 neuron projection membrane; GO:0016327 apicolateral plasma membrane; GO:0044309 neuron spine; GO:0098590 plasma membrane region; GO:0031256 leading edge membrane; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0014069 postsynaptic density; GO:0097060 synaptic membrane; GO:0030175 filopodium; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0098984 neuron to neuron synapse; GO:0044456 synapse part; GO:0031252 cell leading edge; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0042995 cell projection; GO:0031226 intrinsic component of plasma membrane; GO:0044463 cell projection part; GO:0016021 integral component of membrane; GO:0031527 filopodium membrane; GO:0045202 synapse; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0030424 axon; GO:0043226 organelle; GO:0005634 nucleus; GO:0036477 somatodendritic compartment; GO:0044459 plasma membrane part; GO:0098794 postsynapse; GO:0031253 cell projection membrane; GO:0032590 dendrite membrane; GO:0099572 postsynaptic specialization; GO:0044444 cytoplasmic part; GO:0032591 dendritic spine membrane; ","GO:0031750 D3 dopamine receptor binding; GO:0005515 protein binding; GO:0001664 G-protein coupled receptor binding; GO:0005102 receptor binding; GO:0005488 binding; GO:0050780 dopamine receptor binding; ","K16519"]
["O75821","Eukaryotic translation initiation factor 3 subunit G OS=Homo sapiens OX=9606 GN=EIF3G","EIF3G",35.611,23.951,24.4,7,10,7,0.916,0.908,0.956,1.061,1.13,1.071,1.173,0.0032,"nucleus\r","GO:0075525 viral translational termination-reinitiation; GO:0019081 viral translation; GO:0006518 peptide metabolic process; GO:0019058 viral life cycle; GO:0044267 cellular protein metabolic process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0016032 viral process; GO:0006413 translational initiation; GO:0019080 viral gene expression; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006412 translation; GO:0009059 macromolecule biosynthetic process; GO:0044419 interspecies interaction between organisms; GO:0009987 cellular process; GO:0043043 peptide biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0043603 cellular amide metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0051704 multi-organism process; GO:0044249 cellular biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0048471 perinuclear region of cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0043234 protein complex; GO:0005829 cytosol; GO:0005623 cell; GO:0005852 eukaryotic translation initiation factor 3 complex; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0008135 translation factor activity, RNA binding; GO:0003723 RNA binding; GO:1901265 nucleoside phosphate binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0003743 translation initiation factor activity; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0036094 small molecule binding; ","K03248","EIF3G; translation initiation factor 3 subunit G","hsa03013 RNA transport - Homo sapiens (human); ","IPR000504; IPR024675; IPR012677; IPR034240; ","\"RNA recognition motif domain; Eukaryotic translation initiation factor 3 subunit G, N-terminal; Nucleotide-binding alpha-beta plait domain; eIF3G, RNA recognition motif; \"\r"]
["O75822","Eukaryotic translation initiation factor 3 subunit J OS=Homo sapiens OX=9606 GN=EIF3J","EIF3J",29.062,27.007,20.9,6,8,6,0.824,0.875,0.834,1.13,1.132,1.165,1.353,1.35E-4,"nucleus\r","GO:0006518 peptide metabolic process; GO:0043043 peptide biosynthetic process; GO:0044267 cellular protein metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0009058 biosynthetic process; GO:0043603 cellular amide metabolic process; GO:0044238 primary metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0006413 translational initiation; GO:0034641 cellular nitrogen compound metabolic process; GO:0010467 gene expression; GO:0043170 macromolecule metabolic process; GO:0043604 amide biosynthetic process; GO:0019538 protein metabolic process; GO:0006412 translation; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:1901564 organonitrogen compound metabolic process; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0043234 protein complex; GO:0005829 cytosol; GO:0005623 cell; GO:0005852 eukaryotic translation initiation factor 3 complex; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0008135 translation factor activity, RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0003743 translation initiation factor activity; GO:0005515 protein binding; ","K03245","EIF3J; translation initiation factor 3 subunit J","hsa03013 RNA transport - Homo sapiens (human); ","IPR023194; ","Eukaryotic translation initiation factor 3-like domain; \r"]
["O75828","Carbonyl reductase [NADPH] 3 OS=Homo sapiens OX=9606 GN=CBR3","CBR3",30.85,62.479,54.5,11,22,9,0.963,0.949,0.978,1.112,1.006,1.09,1.11,0.0313,"mitochondria\r","GO:0071466 cellular response to xenobiotic stimulus; GO:0042182 ketone catabolic process; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0050877 neurological system process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0051187 cofactor catabolic process; GO:0009410 response to xenobiotic stimulus; GO:0006805 xenobiotic metabolic process; GO:0042180 cellular ketone metabolic process; GO:0050890 cognition; GO:0044248 cellular catabolic process; GO:1901662 quinone catabolic process; GO:0009987 cellular process; GO:0070887 cellular response to chemical stimulus; GO:0051716 cellular response to stimulus; GO:0003008 system process; GO:0055114 oxidation-reduction process; GO:0044712 single-organism catabolic process; GO:0044281 small molecule metabolic process; GO:1901661 quinone metabolic process; GO:0044763 single-organism cellular process; GO:0042376 phylloquinone catabolic process; GO:0044282 small molecule catabolic process; GO:0006732 coenzyme metabolic process; GO:0032501 multicellular organismal process; GO:0042374 phylloquinone metabolic process; GO:0051186 cofactor metabolic process; GO:1901575 organic substance catabolic process; GO:0042221 response to chemical; GO:0044710 single-organism metabolic process; GO:0009109 coenzyme catabolic process; GO:0009056 catabolic process; ","GO:0043229 intracellular organelle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0070402 NADPH binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0048037 cofactor binding; GO:0016491 oxidoreductase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016614 oxidoreductase activity, acting on CH-OH group of donors; GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; GO:0003824 catalytic activity; GO:0005488 binding; GO:0000253 3-keto sterol reductase activity; GO:0004090 carbonyl reductase (NADPH) activity; GO:0050661 NADP binding; GO:0043168 anion binding; GO:0050662 coenzyme binding; GO:0036094 small molecule binding; ","K00084","CBR3; carbonyl reductase 3 [EC:1.1.1.184]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00980 Metabolism of xenobiotics by cytochrome P450 - Homo sapiens (human); hsa00590 Arachidonic acid metabolism - Homo sapiens (human); ","IPR016040; ","NAD(P)-binding domain; \r"]
["O75832","26S proteasome non-ATPase regulatory subunit 10 OS=Homo sapiens OX=9606 GN=PSMD10","PSMD10",24.428,76.245,23.9,4,4,4,1.015,1.061,0.988,1.042,0.959,1.017,0.985,0.66,"cytoplasm\r",{"$cut":{"chars":20572,"head":"GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0010941 regulation of cell death; GO:0010608 posttranscriptional regulation of gene expression; GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0051443 positive regulation of ubiquitin-protein transferase activity; GO:0090201 negative regulation of release of cytochrome c from mitochondria; GO:0090317 negative regulation of intracellular protein transport; GO:0031347 regulation of defense response; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0010821 regulation of mitochondrion organization; GO:0032088 negative regulation of NF-kappaB transcription factor activity; GO:0045927 positive regulation of growth; GO:0001558 regulation of cell growth; GO:0071900 regulation of protein serine/threonine kinase activity; GO:1903364 positive regulation of cellular protein catabolic process; GO:0008152 metabolic process; GO:0065003 macromolecular complex assembly; GO:0044093 positive regulation of molecular function; GO:0090263 positive regulation of canonical Wnt signaling pathway; GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0016055 Wnt signaling pathway; GO:1900181 negative regulation of protein localization to nucleus; GO:0051051 negative regulation of transport; GO:0051220 cytoplasmic sequestering of protein; GO:0000278 mitotic cell cycle; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0006521 regulation of cellular amino acid metabolic process; GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity; GO:0030307 positive regulation of cell growth; GO:0080090 regulation of primary metabolic process; GO:0010972 negative regulation of G2/M transition of mitotic cell cycle; GO:0044763 single-organism cellular process; GO:0060828 regulation of canonical Wnt signaling pathway; GO:0043086 negative regulation of catalytic activity; GO:0033209 tumor necrosis factor-mediated signaling pathway; GO:0050776 regulation of immune response; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0006810 transport; GO:0000165 MAPK cascade; GO:1901575 organic substance catabolic process; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0007267 cell-cell signaling; GO:0002223 stimulatory C-type lectin receptor signaling pathway; GO:0080135 regulation of cellular response to stress; GO:1902532 negative regulation of intracellular signal transduction; GO:0030163 protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0061136 regulation of proteasomal protein catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0060071 Wnt signaling pathway, planar cell polarity pathway; GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:0051223 regulation of protein transport; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0060548 negative regulation of cell death; GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator; GO:0016310 phosphorylation; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0043487 regulation of RNA stability; GO:0000209 protein polyubiquitination; GO:0042990 regulation of transcription factor import into nucleus; GO:0045892 negative regulation of transcription, DNA-templated; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0009889 regulation of biosynthetic process; GO:0009896 positive regulation of catabolic process; GO:0043620 regulation of DNA-templated transcription in response to stress; GO:0070482 resp"}},"GO:0005838 proteasome regulatory particle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:1905369 endopeptidase complex; GO:0005856 cytoskeleton; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0022624 proteasome accessory complex; GO:0005622 intracellular; GO:0044464 cell part; GO:1905368 peptidase complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0000502 proteasome complex; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0045111 intermediate filament cytoskeleton; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0008134 transcription factor binding; GO:0005488 binding; ","K06694",null,null,"IPR020683; ","Ankyrin repeat-containing domain; \r"]
["O75844","CAAX prenyl protease 1 homolog OS=Homo sapiens OX=9606 GN=ZMPSTE24","ZMPSTE24",54.812,18.078,11.4,5,6,5,0.975,0.922,0.974,1.065,1.031,1.005,1.08,0.0365,"plasma membrane\r","GO:0016043 cellular component organization; GO:0006997 nucleus organization; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0010256 endomembrane system organization; GO:0044257 cellular protein catabolic process; GO:0071586 CAAX-box protein processing; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0016485 protein processing; GO:0044237 cellular metabolic process; GO:0006998 nuclear envelope organization; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0044248 cellular catabolic process; GO:0006508 proteolysis; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0009987 cellular process; GO:0043632 modification-dependent macromolecule catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0019941 modification-dependent protein catabolic process; GO:0044763 single-organism cellular process; GO:0044802 single-organism membrane organization; GO:0044238 primary metabolic process; GO:1901575 organic substance catabolic process; GO:0030327 prenylated protein catabolic process; GO:0006996 organelle organization; GO:0030163 protein catabolic process; GO:0009057 macromolecule catabolic process; GO:0061024 membrane organization; GO:0044260 cellular macromolecule metabolic process; GO:0080120 CAAX-box protein maturation; GO:0010467 gene expression; GO:0051604 protein maturation; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0031965 nuclear membrane; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0019866 organelle inner membrane; GO:1903561 extracellular vesicle; GO:0031227 intrinsic component of endoplasmic reticulum membrane; GO:0043227 membrane-bounded organelle; GO:0005637 nuclear inner membrane; GO:0005789 endoplasmic reticulum membrane; GO:0043229 intracellular organelle; GO:0005635 nuclear envelope; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044432 endoplasmic reticulum part; GO:0031975 envelope; GO:0030176 integral component of endoplasmic reticulum membrane; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0004175 endopeptidase activity; GO:0008238 exopeptidase activity; GO:0004222 metalloendopeptidase activity; GO:0008233 peptidase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0008235 metalloexopeptidase activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0016787 hydrolase activity; GO:0008237 metallopeptidase activity; ","K06013","STE24; STE24 endopeptidase [EC:3.4.24.84]","hsa00900 Terpenoid backbone biosynthesis - Homo sapiens (human); ","IPR001915; IPR032456; ","\"Peptidase M48; CAAX prenyl protease 1, N-terminal; \"\r"]
["O75874","Isocitrate dehydrogenase [NADP] cytoplasmic OS=Homo sapiens OX=9606 GN=IDH1","IDH1",46.659,128.81,48.6,21,48,20,1.077,1.087,1.071,0.907,0.944,0.918,0.856,0.000244,"cytoplasm\r","GO:0019362 pyridine nucleotide metabolic process; GO:0045321 leukocyte activation; GO:0006518 peptide metabolic process; GO:0022414 reproductive process; GO:0019216 regulation of lipid metabolic process; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0044262 cellular carbohydrate metabolic process; GO:0044702 single organism reproductive process; GO:0048545 response to steroid hormone; GO:0009719 response to endogenous stimulus; GO:0032787 monocarboxylic acid metabolic process; GO:0046487 glyoxylate metabolic process; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0006790 sulfur compound metabolic process; GO:0072350 tricarboxylic acid metabolic process; GO:0014070 response to organic cyclic compound; GO:0003006 developmental process involved in reproduction; GO:0002443 leukocyte mediated immunity; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0060696 regulation of phospholipid catabolic process; GO:0009894 regulation of catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006081 cellular aldehyde metabolic process; GO:0006732 coenzyme metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0005975 carbohydrate metabolic process; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:0048513 animal organ development; GO:0044710 single-organism metabolic process; GO:0046890 regulation of lipid biosynthetic process; GO:0008585 female gonad development; GO:0050994 regulation of lipid catabolic process; GO:0043436 oxoacid metabolic process; GO:0000003 reproduction; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0006097 glyoxylate cycle; GO:0002283 neutrophil activation involved in immune response; GO:0046496 nicotinamide nucleotide metabolic process; GO:1903725 regulation of phospholipid metabolic process; GO:0008406 gonad development; GO:0046545 development of primary female sexual characteristics; GO:0046483 heterocycle metabolic process; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0007548 sex differentiation; GO:0007275 multicellular organism development; GO:0061458 reproductive system development; GO:0006950 response to stress; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0006099 tricarboxylic acid cycle; GO:0002376 immune system process; GO:0006102 isocitrate metabolic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0002263 cell activation involved in immune response; GO:0045055 regulated exocytosis; GO:0006793 phosphorus metabolic process; GO:0019637 organophosphate metabolic process; GO:0001775 cell activation; GO:0051179 localization; GO:0006955 immune response; GO:0006887 exocytosis; GO:1901564 organonitrogen compound metabolic process; GO:0006739 NADP metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0072524 pyridine-containing compound metabolic process; GO:0046660 female sex differentiation; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0071071 regulation of phospholipid biosynthetic process; GO:0006753 nucleoside phosphate metabolic process; GO:0006979 response to oxidative stress; GO:0006749 glutathione metabolic process; GO:0006103 2-oxoglutarate metabolic process; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:0031326 regulation of cellular biosynthetic process; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0055114 oxidation-reduction process; GO:0002446 neutrophil mediated immunity; GO:0048608 reproductive structure development; GO:1901360 organic cyclic compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0051186 cofactor metabolic process; GO:0006101 citrate metabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0006740 NADPH regeneration; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0032940 secretion by cell; GO:0015980 energy derivation by oxidation of organic compounds; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0043299 leukocyte degranulation; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:0043648 dicarboxylic acid metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0002252 immune effector process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0033993 response to lipid; GO:0006575 cellular modified amino acid metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0036230 granulocyte activation; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0045137 development of primary sexual characteristics; GO:0006807 nitrogen compound metabolic process; GO:0043312 neutrophil degranulation; GO:0045333 cellular respiration; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0009060 aerobic respiration; GO:0044767 single-organism developmental process; GO:0019752 carboxylic acid metabolic process; GO:0009725 response to hormone; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:1904724 tertiary granule lumen; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044438 microbody part; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005782 peroxisomal matrix; GO:0005622 intracellular; GO:0044464 cell part; GO:0042579 microbody; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0044439 peroxisomal part; GO:0005777 peroxisome; GO:0070820 tertiary granule; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031907 microbody lumen; GO:0060205 cytoplasmic vesicle lumen; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0000287 magnesium ion binding; GO:1901265 nucleoside phosphate binding; GO:0005102 receptor binding; GO:0046983 protein dimerization activity; GO:0043167 ion binding; GO:0004448 isocitrate dehydrogenase activity; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0048037 cofactor binding; GO:0016491 oxidoreductase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0016614 oxidoreductase activity, acting on CH-OH group of donors; GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; GO:0050839 cell adhesion molecule binding; GO:0042802 identical protein binding; GO:0051990 (R)-2-hydroxyglutarate dehydrogenase activity; GO:0051287 NAD binding; GO:0003824 catalytic activity; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0045296 cadherin binding; GO:0050661 NADP binding; GO:0004450 isocitrate dehydrogenase (NADP+) activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0036094 small molecule binding; GO:0050662 coenzyme binding; ","K00031","IDH1; isocitrate dehydrogenase [EC:1.1.1.42]","hsa01210 2-Oxocarboxylic acid metabolism - Homo sapiens (human); hsa00480 Glutathione metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00020 Citrate cycle (TCA cycle) - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); hsa05230 Central carbon metabolism in cancer - Homo sapiens (human); hsa04146 Peroxisome - Homo sapiens (human); hsa01230 Biosynthesis of amino acids - Homo sapiens (human); ","IPR024084; ","Isopropylmalate dehydrogenase-like domain; \r"]
["O75882","Attractin OS=Homo sapiens OX=9606 GN=ATRN","ATRN",158.54,7.4148,1.6,2,3,2,1.036,1.088,0.908,0.972,0.965,1.044,0.983,0.817,"plasma membrane\r","GO:0044707 single-multicellular organism process; GO:0040008 regulation of growth; GO:0007272 ensheathment of neurons; GO:0007420 brain development; GO:0008366 axon ensheathment; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0048638 regulation of developmental growth; GO:0051239 regulation of multicellular organismal process; GO:0006979 response to oxidative stress; GO:0060322 head development; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0030902 hindbrain development; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0040014 regulation of multicellular organism growth; GO:0006950 response to stress; GO:0048731 system development; GO:0044763 single-organism cellular process; GO:0032501 multicellular organismal process; GO:0021549 cerebellum development; GO:0042552 myelination; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0044767 single-organism developmental process; GO:0007417 central nervous system development; GO:0006954 inflammatory response; GO:0043473 pigmentation; GO:0022037 metencephalon development; GO:0006952 defense response; GO:0050793 regulation of developmental process; GO:0048856 anatomical structure development; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0031226 intrinsic component of plasma membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0030246 carbohydrate binding; GO:0060089 molecular transducer activity; GO:0005515 protein binding; GO:0004872 receptor activity; GO:0005488 binding; ",{"$nulls":3},"IPR034011; IPR000859; IPR011043; IPR016187; IPR000742; IPR016201; IPR016186; IPR001304; IPR002049; IPR015915; ","\"Attractin-like, C-type lectin-like domain; CUB domain; Galactose oxidase/kelch, beta-propeller; C-type lectin fold; EGF-like domain; PSI domain; C-type lectin-like/link domain; C-type lectin-like; Laminin EGF domain; Kelch-type beta propeller; \"\r"]
["O75884","Putative hydrolase RBBP9 OS=Homo sapiens OX=9606 GN=RBBP9","RBBP9",21,54.963,31.2,4,6,4,0.957,0.961,1.056,1.05,1.025,1.033,1.045,0.243,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0050789 regulation of biological process; GO:0042127 regulation of cell proliferation; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; ","K07002",null,null,"IPR029058; ","Alpha/Beta hydrolase fold; \r"]
["O75886","Signal transducing adapter molecule 2 OS=Homo sapiens OX=9606 GN=STAM2","STAM2",58.164,8.1219,11,5,5,3,1.13,1.011,1.011,0.979,0.926,0.959,0.909,0.0795,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0070646 protein modification by small protein removal; GO:0010256 endomembrane system organization; GO:0009968 negative regulation of signal transduction; GO:1901185 negative regulation of ERBB signaling pathway; GO:0023051 regulation of signaling; GO:0006914 autophagy; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0010646 regulation of cell communication; GO:0022607 cellular component assembly; GO:0036258 multivesicular body assembly; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0016236 macroautophagy; GO:0036257 multivesicular body organization; GO:0070647 protein modification by small protein conjugation or removal; GO:0006810 transport; GO:0016197 endosomal transport; GO:0050789 regulation of biological process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0036211 protein modification process; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0044267 cellular protein metabolic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0016579 protein deubiquitination; GO:0071704 organic substance metabolic process; GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:1901184 regulation of ERBB signaling pathway; GO:0070925 organelle assembly; GO:0006886 intracellular protein transport; GO:0044248 cellular catabolic process; GO:0006508 proteolysis; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0009966 regulation of signal transduction; GO:0016050 vesicle organization; GO:0071702 organic substance transport; GO:0048585 negative regulation of response to stimulus; GO:0044238 primary metabolic process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0042058 regulation of epidermal growth factor receptor signaling pathway; GO:0051179 localization; GO:0043412 macromolecule modification; GO:0007032 endosome organization; GO:0009056 catabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0031974 membrane-enclosed lumen; GO:0036452 ESCRT complex; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005768 endosome; GO:0031901 early endosome membrane; GO:0043227 membrane-bounded organelle; GO:0033565 ESCRT-0 complex; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0010008 endosome membrane; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0005829 cytosol; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0005488 binding; ","K04705","STAM; signal transducing adaptor molecule","hsa04144 Endocytosis - Homo sapiens (human); hsa04630 Jak-STAT signaling pathway - Homo sapiens (human); ","IPR002014; IPR001452; IPR008942; ","VHS domain; SH3 domain; ENTH/VHS; \r"]
["O75891","Cytosolic 10-formyltetrahydrofolate dehydrogenase OS=Homo sapiens OX=9606 GN=ALDH1L1","ALDH1L1",98.828,16.153,8.5,7,9,4,1.146,1.117,1.155,0.973,0.789,0.851,0.764,0.0118,"cytoplasm\r","GO:0043648 dicarboxylic acid metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0009258 10-formyltetrahydrofolate catabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0046655 folic acid metabolic process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0006766 vitamin metabolic process; GO:0008152 metabolic process; GO:0043649 dicarboxylic acid catabolic process; GO:0006730 one-carbon metabolic process; GO:0051187 cofactor catabolic process; GO:0046483 heterocycle metabolic process; GO:0006575 cellular modified amino acid metabolic process; GO:1901361 organic cyclic compound catabolic process; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009987 cellular process; GO:0006767 water-soluble vitamin metabolic process; GO:0042560 pteridine-containing compound catabolic process; GO:0046653 tetrahydrofolate metabolic process; GO:0055114 oxidation-reduction process; GO:0044712 single-organism catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0044282 small molecule catabolic process; GO:0006732 coenzyme metabolic process; GO:0043603 cellular amide metabolic process; GO:0042558 pteridine-containing compound metabolic process; GO:0051186 cofactor metabolic process; GO:0046395 carboxylic acid catabolic process; GO:0019439 aromatic compound catabolic process; GO:1901575 organic substance catabolic process; GO:1901565 organonitrogen compound catabolic process; GO:0042219 cellular modified amino acid catabolic process; GO:0044710 single-organism metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0016054 organic acid catabolic process; GO:0009109 coenzyme catabolic process; GO:0009256 10-formyltetrahydrofolate metabolic process; GO:0006082 organic acid metabolic process; GO:0006760 folic acid-containing compound metabolic process; GO:0009056 catabolic process; GO:0009397 folic acid-containing compound catabolic process; GO:0043436 oxoacid metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0046700 heterocycle catabolic process; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors; GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor; GO:0003824 catalytic activity; GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors; GO:0016741 transferase activity, transferring one-carbon groups; GO:0016742 hydroxymethyl-, formyl- and related transferase activity; GO:0016155 formyltetrahydrofolate dehydrogenase activity; GO:0016740 transferase activity; GO:0016491 oxidoreductase activity; GO:0004029 aldehyde dehydrogenase (NAD) activity; ","K00289","ALDH1L; formyltetrahydrofolate dehydrogenase [EC:1.5.1.6]","hsa00670 One carbon pool by folate - Homo sapiens (human); ","IPR005793; IPR016161; IPR015590; IPR016162; IPR009081; IPR016163; IPR011034; IPR002376; ","\"Formyl transferase, C-terminal; Aldehyde/histidinol dehydrogenase; Aldehyde dehydrogenase domain; Aldehyde dehydrogenase N-terminal domain; Phosphopantetheine binding ACP domain; Aldehyde dehydrogenase, C-terminal; Formyl transferase, C-terminal-like; Formyl transferase, N-terminal; \"\r"]
["O75915","PRA1 family protein 3 OS=Homo sapiens OX=9606 GN=ARL6IP5","ARL6IP5",21.614,70.711,27.7,6,15,6,1.032,1.045,0.916,0.989,0.999,1,0.998,0.999,"plasma membrane\r","GO:0044700 single organism signaling; GO:0032872 regulation of stress-activated MAPK cascade; GO:0065008 regulation of biological quality; GO:0010941 regulation of cell death; GO:0032270 positive regulation of cellular protein metabolic process; GO:0002036 regulation of L-glutamate transport; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0032891 negative regulation of organic acid transport; GO:0044765 single-organism transport; GO:0051051 negative regulation of transport; GO:0051953 negative regulation of amine transport; GO:0052548 regulation of endopeptidase activity; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0051174 regulation of phosphorus metabolic process; GO:0010950 positive regulation of endopeptidase activity; GO:0051956 negative regulation of amino acid transport; GO:0080090 regulation of primary metabolic process; GO:0043269 regulation of ion transport; GO:0044763 single-organism cellular process; GO:0031323 regulation of cellular metabolic process; GO:0046942 carboxylic acid transport; GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0006810 transport; GO:0080135 regulation of cellular response to stress; GO:0051336 regulation of hydrolase activity; GO:0032874 positive regulation of stress-activated MAPK cascade; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0010604 positive regulation of macromolecule metabolic process; GO:0010952 positive regulation of peptidase activity; GO:0043068 positive regulation of programmed cell death; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0097190 apoptotic signaling pathway; GO:2001056 positive regulation of cysteine-type endopeptidase activity; GO:0031399 regulation of protein modification process; GO:0043067 regulation of programmed cell death; GO:0015807 L-amino acid transport; GO:0080134 regulation of response to stress; GO:0048519 negative regulation of biological process; GO:0010917 negative regulation of mitochondrial membrane potential; GO:1902578 single-organism localization; GO:0051345 positive regulation of hydrolase activity; GO:0006865 amino acid transport; GO:0009966 regulation of signal transduction; GO:1902531 regulation of intracellular signal transduction; GO:0006950 response to stress; GO:0036473 cell death in response to oxidative stress; GO:0071702 organic substance transport; GO:0030162 regulation of proteolysis; GO:0015849 organic acid transport; GO:0051955 regulation of amino acid transport; GO:0051247 positive regulation of protein metabolic process; GO:0006811 ion transport; GO:0031325 positive regulation of cellular metabolic process; GO:0006835 dicarboxylic acid transport; GO:0012501 programmed cell death; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0032890 regulation of organic acid transport; GO:0044070 regulation of anion transport; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:0070302 regulation of stress-activated protein kinase signaling cascade; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0006915 apoptotic process; GO:0070304 positive regulation of stress-activated protein kinase signaling cascade; GO:0006979 response to oxidative stress; GO:0034599 cellular response to oxidative stress; GO:0070887 cellular response to chemical stimulus; GO:0045937 positive regulation of phosphate metabolic process; GO:2000116 regulation of cysteine-type endopeptidase activity; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0015800 acidic amino acid transport; GO:0042391 regulation of membrane potential; GO:0010942 positive regulation of cell death; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0042221 response to chemical; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0052547 regulation of peptidase activity; GO:0060255 regulation of macromolecule metabolic process; GO:0043065 positive regulation of apoptotic process; GO:0050896 response to stimulus; GO:0097193 intrinsic apoptotic signaling pathway; GO:0045862 positive regulation of proteolysis; GO:0051952 regulation of amine transport; GO:0043408 regulation of MAPK cascade; GO:0023056 positive regulation of signaling; GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:1903792 negative regulation of anion transport; GO:0043271 negative regulation of ion transport; GO:0035556 intracellular signal transduction; GO:0051049 regulation of transport; GO:0001932 regulation of protein phosphorylation; GO:0031401 positive regulation of protein modification process; GO:0015813 L-glutamate transport; GO:0001934 positive regulation of protein phosphorylation; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0006820 anion transport; GO:0015711 organic anion transport; GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress; GO:0002037 negative regulation of L-glutamate transport; GO:0008219 cell death; GO:0051246 regulation of protein metabolic process; GO:0045837 negative regulation of membrane potential; GO:0009967 positive regulation of signal transduction; GO:0043410 positive regulation of MAPK cascade; GO:0071705 nitrogen compound transport; GO:0051881 regulation of mitochondrial membrane potential; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044432 endoplasmic reticulum part; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ","K20393"]
["O75923","Dysferlin OS=Homo sapiens OX=9606 GN=DYSF","DYSF",237.29,21.644,5,9,11,8,1.03,0.98,0.963,1.028,0.971,1.001,1.009,0.742,"cytoplasm\r","GO:0090174 organelle membrane fusion; GO:0016043 cellular component organization; GO:0003012 muscle system process; GO:0010256 endomembrane system organization; GO:0003008 system process; GO:0006950 response to stress; GO:0016192 vesicle-mediated transport; GO:0001778 plasma membrane repair; GO:0044763 single-organism cellular process; GO:0016050 vesicle organization; GO:0061025 membrane fusion; GO:0044699 single-organism process; GO:0044802 single-organism membrane organization; GO:0048284 organelle fusion; GO:0007009 plasma membrane organization; GO:0050896 response to stimulus; GO:0032501 multicellular organismal process; GO:0051234 establishment of localization; GO:0006810 transport; GO:0009611 response to wounding; GO:1902589 single-organism organelle organization; GO:0006936 muscle contraction; GO:0042060 wound healing; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0006906 vesicle fusion; GO:0044801 single-organism membrane fusion; GO:0051179 localization; GO:0009987 cellular process; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0030315 T-tubule; GO:0070062 extracellular exosome; GO:0005815 microtubule organizing center; GO:0015630 microtubule cytoskeleton; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0030027 lamellipodium; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0030139 endocytic vesicle; GO:0043227 membrane-bounded organelle; GO:0031252 cell leading edge; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0042995 cell projection; GO:0005770 late endosome; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0042383 sarcolemma; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005544 calcium-dependent phospholipid binding; GO:0005488 binding; GO:0005543 phospholipid binding; GO:0043167 ion binding; GO:0008289 lipid binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0005515 protein binding; GO:0005509 calcium ion binding; ","K18261",null,null,"IPR012561; IPR006614; IPR012560; IPR012968; IPR032362; IPR000008; ","\"Ferlin B-domain; Peroxin/Ferlin domain; Ferlin A-domain; FerIin domain; Ferlin, C-terminal domain; C2 domain; \"\r"]
["O75935","Dynactin subunit 3 OS=Homo sapiens OX=9606 GN=DCTN3","DCTN3",21.119,8.3618,17.7,4,8,4,1.059,1.036,1.073,0.974,1.008,0.986,0.937,0.0104,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0007067 mitotic nuclear division; GO:0048285 organelle fission; GO:0048193 Golgi vesicle transport; GO:0060271 cilium assembly; GO:0044699 single-organism process; GO:0097711 ciliary basal body docking; GO:0022406 membrane docking; GO:1903047 mitotic cell cycle process; GO:0044782 cilium organization; GO:0051234 establishment of localization; GO:0051649 establishment of localization in cell; GO:0000910 cytokinesis; GO:0022607 cellular component assembly; GO:0070925 organelle assembly; GO:0044770 cell cycle phase transition; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0009987 cellular process; GO:0044772 mitotic cell cycle phase transition; GO:0000278 mitotic cell cycle; GO:0016192 vesicle-mediated transport; GO:0048002 antigen processing and presentation of peptide antigen; GO:0044763 single-organism cellular process; GO:0002376 immune system process; GO:0002495 antigen processing and presentation of peptide antigen via MHC class II; GO:0007017 microtubule-based process; GO:0030031 cell projection assembly; GO:0051641 cellular localization; GO:0006810 transport; GO:1902589 single-organism organelle organization; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0019882 antigen processing and presentation; GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; GO:0030030 cell projection organization; GO:0006996 organelle organization; GO:0000280 nuclear division; GO:0044839 cell cycle G2/M phase transition; GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II; GO:0022402 cell cycle process; GO:0051301 cell division; GO:0051179 localization; GO:0000086 G2/M transition of mitotic cell cycle; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; ","GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0005869 dynactin complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0032155 cell division site part; GO:0000777 condensed chromosome kinetochore; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0000793 condensed chromosome; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0005815 microtubule organizing center; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0048471 perinuclear region of cytoplasm; GO:0032154 cleavage furrow; GO:0043227 membrane-bounded organelle; GO:0000776 kinetochore; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0097610 cell surface furrow; GO:0043232 intracellular non-membrane-bounded organelle; GO:0000779 condensed chromosome, centromeric region; GO:0044430 cytoskeletal part; GO:0032153 cell division site; GO:0044446 intracellular organelle part; GO:0030496 midbody; GO:0031981 nuclear lumen; GO:0005875 microtubule associated complex; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0005819 spindle; GO:0015629 actin cytoskeleton; GO:0098687 chromosomal region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005813 centrosome; GO:0000775 chromosome, centromeric region; GO:0009986 cell surface; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0005198 structural molecule activity; GO:0005488 binding; ","K10425"]
["O75936","Gamma-butyrobetaine dioxygenase OS=Homo sapiens OX=9606 GN=BBOX1","BBOX1",44.714,13.681,15,5,5,5,1.075,1.035,1.057,0.948,0.963,0.937,0.899,1.42E-3,"cytoplasm\r","GO:0055114 oxidation-reduction process; GO:0044699 single-organism process; GO:0097164 ammonium ion metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0006578 amino-acid betaine biosynthetic process; GO:0009058 biosynthetic process; GO:0045329 carnitine biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:0006577 amino-acid betaine metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0044710 single-organism metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009437 carnitine metabolic process; GO:0009987 cellular process; GO:1901564 organonitrogen compound metabolic process; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005506 iron ion binding; GO:0042802 identical protein binding; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0051213 dioxygenase activity; GO:0005488 binding; GO:0043167 ion binding; GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; GO:0008270 zinc ion binding; GO:0008336 gamma-butyrobetaine dioxygenase activity; GO:0016491 oxidoreductase activity; ","K00471","E1.14.11.1; gamma-butyrobetaine dioxygenase [EC:1.14.11.1]","hsa00310 Lysine degradation - Homo sapiens (human); ","IPR010376; IPR003819; ","Domain of unknown function DUF971; TauD/TfdA-like domain; \r"]
["O75937","DnaJ homolog subfamily C member 8 OS=Homo sapiens OX=9606 GN=DNAJC8","DNAJC8",29.841,29.599,35.6,10,11,10,0.979,0.964,1.013,1.064,0.972,1.002,1.028,0.426,"nucleus\r","GO:0006396 RNA processing; GO:0006725 cellular aromatic compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0008152 metabolic process; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0090304 nucleic acid metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0009987 cellular process; GO:0008380 RNA splicing; GO:0016071 mRNA metabolic process; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0045171 intercellular bridge; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ",null,"K09528",null,null,"IPR001623; ","DnaJ domain; \r"]
["O75947","ATP synthase subunit d, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5H","ATP5H",18.491,58.281,69.6,10,17,10,1.036,0.992,1.064,0.944,0.985,1,0.947,0.113,"cytoplasm\r","GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0090662 ATP hydrolysis coupled transmembrane transport; GO:0009117 nucleotide metabolic process; GO:0006839 mitochondrial transport; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0046129 purine ribonucleoside biosynthetic process; GO:0009163 nucleoside biosynthetic process; GO:0009156 ribonucleoside monophosphate biosynthetic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0046390 ribose phosphate biosynthetic process; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:1901137 carbohydrate derivative biosynthetic process; GO:0006753 nucleoside phosphate metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0009145 purine nucleoside triphosphate biosynthetic process; GO:0044765 single-organism transport; GO:0018130 heterocycle biosynthetic process; GO:0098655 cation transmembrane transport; GO:0009206 purine ribonucleoside triphosphate biosynthetic process; GO:0044281 small molecule metabolic process; GO:0006754 ATP biosynthetic process; GO:0044763 single-organism cellular process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0015985 energy coupled proton transport, down electrochemical gradient; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0009168 purine ribonucleoside monophosphate biosynthetic process; GO:1902582 single-organism intracellular transport; GO:0042451 purine nucleoside biosynthetic process; GO:0090407 organophosphate biosynthetic process; GO:0006810 transport; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0072522 purine-containing compound biosynthetic process; GO:0015986 ATP synthesis coupled proton transport; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0006164 purine nucleotide biosynthetic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0098662 inorganic cation transmembrane transport; GO:0009201 ribonucleoside triphosphate biosynthetic process; GO:0046907 intracellular transport; GO:0034220 ion transmembrane transport; GO:0009165 nucleotide biosynthetic process; GO:0042776 mitochondrial ATP synthesis coupled proton transport; GO:0006725 cellular aromatic compound metabolic process; GO:0009259 ribonucleotide metabolic process; GO:0009142 nucleoside triphosphate biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0006812 cation transport; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:1990542 mitochondrial transmembrane transport; GO:1901135 carbohydrate derivative metabolic process; GO:1902600 hydrogen ion transmembrane transport; GO:0034641 cellular nitrogen compound metabolic process; GO:1902580 single-organism cellular localization; GO:0099132 ATP hydrolysis coupled cation transmembrane transport; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0099131 ATP hydrolysis coupled ion transmembrane transport; GO:0009987 cellular process; GO:0009119 ribonucleoside metabolic process; GO:0046034 ATP metabolic process; GO:0009124 nucleoside monophosphate biosynthetic process; GO:0044711 single-organism biosynthetic process; GO:0098660 inorganic ion transmembrane transport; GO:0009127 purine nucleoside monophosphate biosynthetic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0042455 ribonucleoside biosynthetic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0006163 purine nucleotide metabolic process; GO:0006818 hydrogen transport; GO:0015992 proton transport; GO:0051641 cellular localization; GO:0046128 purine ribonucleoside metabolic process; GO:0055085 transmembrane transport; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0009152 purine ribonucleotide biosynthetic process; GO:0006793 phosphorus metabolic process; GO:1901659 glycosyl compound biosynthetic process; GO:0006811 ion transport; GO:0009260 ribonucleotide biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0051179 localization; GO:0015672 monovalent inorganic cation transport; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044455 mitochondrial membrane part; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0005740 mitochondrial envelope; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0019866 organelle inner membrane; GO:0000274 mitochondrial proton-transporting ATP synthase, stator stalk; GO:0043227 membrane-bounded organelle; GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain; GO:0005743 mitochondrial inner membrane; GO:0045265 proton-transporting ATP synthase, stator stalk; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0031981 nuclear lumen; GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o); GO:0005829 cytosol; GO:0005576 extracellular region; GO:0045259 proton-transporting ATP synthase complex; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005753 mitochondrial proton-transporting ATP synthase complex; GO:0016469 proton-transporting two-sector ATPase complex; GO:0031975 envelope; GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o); GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0015075 ion transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0015077 monovalent inorganic cation transmembrane transporter activity; GO:0022890 inorganic cation transmembrane transporter activity; GO:0015078 hydrogen ion transmembrane transporter activity; GO:0008324 cation transmembrane transporter activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; ","K02138","ATPeF0D; F-type H+-transporting ATPase subunit d","hsa05010 Alzheimer's disease - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); "]
["O75954","Tetraspanin-9 OS=Homo sapiens OX=9606 GN=TSPAN9","TSPAN9",26.779,8.1928,4.6,1,2,1,0.997,0.939,1.039,0.93,1.016,1.081,1.017,0.772,"plasma membrane\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0051716 cellular response to stimulus; GO:0007165 signal transduction; GO:0050789 regulation of biological process; GO:0007154 cell communication; GO:0007166 cell surface receptor signaling pathway; GO:0044699 single-organism process; GO:0023052 signaling; GO:0050896 response to stimulus; GO:0009987 cellular process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0031226 intrinsic component of plasma membrane; GO:0097197 tetraspanin-enriched microdomain; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0070161 anchoring junction; GO:0031224 intrinsic component of membrane; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0005925 focal adhesion; GO:0044459 plasma membrane part; GO:0044464 cell part; GO:0044425 membrane part; GO:0005912 adherens junction; GO:0030055 cell-substrate junction; GO:0005924 cell-substrate adherens junction; ",null,"K17350",null,null,"IPR008952; ","\"Tetraspanin, EC2 domain; \"\r"]
["O75955","Flotillin-1 OS=Homo sapiens OX=9606 GN=FLOT1","FLOT1",47.355,26.127,13.3,5,6,5,0.99,0.953,0.973,1.067,1.004,0.932,1.03,0.529,"cytoplasm\r","GO:0050658 RNA transport; GO:0044700 single organism signaling; GO:0060627 regulation of vesicle-mediated transport; GO:0044085 cellular component biogenesis; GO:0032481 positive regulation of type I interferon production; GO:0032270 positive regulation of cellular protein metabolic process; GO:0060142 regulation of syncytium formation by plasma membrane fusion; GO:0032989 cellular component morphogenesis; GO:0090002 establishment of protein localization to plasma membrane; GO:0031347 regulation of defense response; GO:0051240 positive regulation of multicellular organismal process; GO:0015931 nucleobase-containing compound transport; GO:0044854 plasma membrane raft assembly; GO:0032879 regulation of localization; GO:0065003 macromolecular complex assembly; GO:0060353 regulation of cell adhesion molecule production; GO:0033227 dsRNA transport; GO:0044093 positive regulation of molecular function; GO:2000047 regulation of cell-cell adhesion mediated by cadherin; GO:0010830 regulation of myotube differentiation; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0008104 protein localization; GO:0051099 positive regulation of binding; GO:0051056 regulation of small GTPase mediated signal transduction; GO:0051147 regulation of muscle cell differentiation; GO:0044765 single-organism transport; GO:0007399 nervous system development; GO:0014070 response to organic cyclic compound; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0051174 regulation of phosphorus metabolic process; GO:0048259 regulation of receptor-mediated endocytosis; GO:0072657 protein localization to membrane; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0048812 neuron projection morphogenesis; GO:0007009 plasma membrane organization; GO:1901888 regulation of cell junction assembly; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0050776 regulation of immune response; GO:0000902 cell morphogenesis; GO:0006810 transport; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051149 positive regulation of muscle cell differentiation; GO:0002682 regulation of immune system process; GO:1901863 positive regulation of muscle tissue development; GO:0051094 positive regulation of developmental process; GO:0048641 regulation of skeletal muscle tissue development; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0033554 cellular response to stress; GO:0034976 response to endoplasmic reticulum stress; GO:0051260 protein homooligomerization; GO:0001819 positive regulation of cytokine production; GO:0031399 regulation of protein modification process; GO:0080134 regulation of response to stress; GO:0051236 establishment of RNA localization; GO:0045597 positive regulation of cell differentiation; GO:0051239 regulation of multicellular organismal process; GO:1990778 protein localization to cell periphery; GO:0051259 protein oligomerization; GO:0009653 anatomical structure morphogenesis; GO:1902578 single-organism localization; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0043062 extracellular structure organization; GO:0007409 axonogenesis; GO:0045844 positive regulation of striated muscle tissue development; GO:1902580 single-organism cellular localization; GO:0007275 multicellular organism development; GO:0031579 membrane raft organization; GO:0034613 cellular protein localization; GO:0009966 regulation of signal transduction; GO:0090150 establishment of protein localization to membrane; GO:0006461 protein complex assembly; GO:0071359 cellular response to dsRNA; GO:1902531 regulation of intracellular signal transduction; GO:0030100 regulation of endocytosis; GO:0045785 positive regulation of cell adhesion; GO:0006950 response to stress; GO:0032648 regulation of interferon-beta production; GO:0048731 system development; GO:0006403 RNA localization; GO:1901739 regulation of myoblast fusion; GO:0050804 modulation of synaptic transmission; GO:0071709 membrane assembly; GO:0071407 cellular response to organic cyclic compound; GO:0071702 organic substance transport; GO:0010033 response to organic substance; GO:0001765 membrane raft assembly; GO:0044091 membrane biogenesis; GO:0030155 regulation of cell adhesion; GO:0045184 establishment of protein localization; GO:0030182 neuron differentiation; GO:0072659 protein localization to plasma membrane; GO:0051247 positive regulation of protein metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0061024 membrane organization; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0035023 regulation of Rho protein signal transduction; GO:0050793 regulation of developmental process; GO:0060355 positive regulation of cell adhesion molecule production; GO:0010256 endomembrane system organization; GO:0048634 regulation of muscle organ development; GO:0048869 cellular developmental process; GO:0048666 neuron development; GO:0023051 regulation of signaling; GO:0032092 positive regulation of protein binding; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:1901741 positive regulation of myoblast fusion; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0050806 positive regulation of synaptic transmission; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0032990 cell part morphogenesis; GO:0022607 cellular component assembly; GO:0045088 regulation of innate immune response; GO:0034141 positive regulation of toll-like receptor 3 signaling pathway; GO:0050657 nucleic acid transport; GO:0022617 extracellular matrix disassembly; GO:0048858 cell projection morphogenesis; GO:0030198 extracellular matrix organization; GO:0033036 macromolecule localization; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0034121 regulation of toll-like receptor signaling pathway; GO:0045937 positive regulation of phosphate metabolic process; GO:0071822 protein complex subunit organization; GO:0051098 regulation of binding; GO:0043331 response to dsRNA; GO:0048522 positive regulation of cellular process; GO:1901890 positive regulation of cell junction assembly; GO:0048636 positive regulation of muscle organ development; GO:0023052 signaling; GO:0051050 positive regulation of transport; GO:0016202 regulation of striated muscle tissue development; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:1901699 cellular response to nitrogen compound; GO:0030030 cell projection organization; GO:0034114 regulation of heterotypic cell-cell adhesion; GO:0032225 regulation of synaptic transmission, dopaminergic; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0048643 positive regulation of skeletal muscle tissue development; GO:0019220 regulation of phosphate metabolic process; GO:0070271 protein complex biogenesis; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0016043 cellular component organization; GO:0051155 positive regulation of striated muscle cell differentiation; GO:0032479 regulation of type I interferon production; GO:0032226 positive regulation of synaptic transmission, dopaminergic; GO:0034123 positive regulation of toll-like receptor signaling pathway; GO:0060255 regulation of macromolecule metabolic process; GO:0045807 positive regulation of endocytosis; GO:0071310 cellular response to organic substance; GO:0046578 regulation of Ras protein signal transduction; GO:0044087 regulation of cellular component biogenesis; GO:1903044 protein localization to membrane raft; GO:0050896 response to stimulus; GO:0060143 positive regulation of syncytium formation by plasma membrane fusion; GO:0048468 cell development; GO:0000904 cell morphogenesis involved in differentiation; GO:0034116 positive regulation of heterotypic cell-cell adhesion; GO:0043393 regulation of protein binding; GO:0030154 cell differentiation; GO:0070528 protein kinase C signaling; GO:0023056 positive regulation of signaling; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:0002090 regulation of receptor internalization; GO:0045595 regulation of cell differentiation; GO:0043330 response to exogenous dsRNA; GO:0022409 positive regulation of cell-cell adhesion; GO:0035556 intracellular signal transduction; GO:0051049 regulation of transport; GO:1901861 regulation of muscle tissue development; GO:0010831 positive regulation of myotube differentiation; GO:0001932 regulation of protein phosphorylation; GO:0031401 positive regulation of protein modification process; GO:0044802 single-organism membrane organization; GO:0001934 positive regulation of protein phosphorylation; GO:0031175 neuron projection development; GO:0048518 positive regulation of biological process; GO:0044857 plasma membrane raft organization; GO:0022407 regulation of cell-cell adhesion; GO:0051641 cellular localization; GO:0043933 macromolecular complex subunit organization; GO:0051153 regulation of striated muscle cell differentiation; GO:0061564 axon development; GO:0032728 positive regulation of interferon-beta production; GO:0070727 cellular macromolecule localization; GO:0071360 cellular response to exogenous dsRNA; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin; GO:0022603 regulation of anatomical structure morphogenesis; GO:0002684 positive regulation of immune system process; GO:0022411 cellular component disassembly; GO:0001817 regulation of cytokine production; GO:0051128 regulation of cellular component organization; GO:0034139 regulation of toll-like receptor 3 signaling pathway; GO:0009967 positive regulation of signal transduction; GO:0044089 positive regulation of cellular component biogenesis; GO:0071705 nitrogen compound transport; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0044450 microtubule organizing center part; GO:0031090 organelle membrane; GO:0098857 membrane microdomain; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0005913 cell-cell adherens junction; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0043228 non-membrane-bounded organelle; GO:0005765 lysosomal membrane; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0098590 plasma membrane region; GO:0005622 intracellular; GO:0005764 lysosome; GO:0098589 membrane region; GO:0030027 lamellipodium; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0016600 flotillin complex; GO:0005924 cell-substrate adherens junction; GO:0000323 lytic vacuole; GO:0031252 cell leading edge; GO:0042995 cell projection; GO:0044430 cytoskeletal part; GO:0098797 plasma membrane protein complex; GO:0070161 anchoring junction; GO:0005901 caveola; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043234 protein complex; GO:0042383 sarcolemma; GO:0043230 extracellular organelle; GO:0016323 basolateral plasma membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0044291 cell-cell contact zone; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005911 cell-cell junction; GO:0048770 pigment granule; GO:0005856 cytoskeleton; GO:0005815 microtubule organizing center; GO:0015630 microtubule cytoskeleton; GO:0044425 membrane part; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0045121 membrane raft; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0001931 uropod; GO:0042470 melanosome; GO:0034451 centriolar satellite; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0031254 cell trailing edge; GO:0016021 integral component of membrane; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0005813 centrosome; GO:0044853 plasma membrane raft; GO:0005774 vacuolar membrane; GO:0044444 cytoplasmic part; ","GO:0002020 protease binding; GO:0035254 glutamate receptor binding; GO:0046982 protein heterodimerization activity; GO:0005102 receptor binding; GO:0005488 binding; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:0035255 ionotropic glutamate receptor binding; GO:0019899 enzyme binding; ","K07192","FLOT; flotillin","hsa04910 Insulin signaling pathway - Homo sapiens (human); ","IPR031905; IPR001107; ","\"Flotillin, C-terminal domain; Band 7 domain; \"\r"]
["O75964","ATP synthase subunit g, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5L","ATP5L",11.428,18.449,43.7,5,8,5,1.015,1.038,1.134,0.995,0.94,0.984,0.916,0.0842,"cytoplasm\r","GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0090662 ATP hydrolysis coupled transmembrane transport; GO:0009117 nucleotide metabolic process; GO:0006839 mitochondrial transport; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0046129 purine ribonucleoside biosynthetic process; GO:0009163 nucleoside biosynthetic process; GO:0009156 ribonucleoside monophosphate biosynthetic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0046390 ribose phosphate biosynthetic process; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:1901137 carbohydrate derivative biosynthetic process; GO:0006753 nucleoside phosphate metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0009145 purine nucleoside triphosphate biosynthetic process; GO:0044765 single-organism transport; GO:0018130 heterocycle biosynthetic process; GO:0098655 cation transmembrane transport; GO:0009206 purine ribonucleoside triphosphate biosynthetic process; GO:0044281 small molecule metabolic process; GO:0006754 ATP biosynthetic process; GO:0044763 single-organism cellular process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0015985 energy coupled proton transport, down electrochemical gradient; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0009168 purine ribonucleoside monophosphate biosynthetic process; GO:1902582 single-organism intracellular transport; GO:0042451 purine nucleoside biosynthetic process; GO:0090407 organophosphate biosynthetic process; GO:0006810 transport; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0072522 purine-containing compound biosynthetic process; GO:0015986 ATP synthesis coupled proton transport; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0006164 purine nucleotide biosynthetic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0098662 inorganic cation transmembrane transport; GO:0009201 ribonucleoside triphosphate biosynthetic process; GO:0046907 intracellular transport; GO:0034220 ion transmembrane transport; GO:0009165 nucleotide biosynthetic process; GO:0042776 mitochondrial ATP synthesis coupled proton transport; GO:0006725 cellular aromatic compound metabolic process; GO:0009259 ribonucleotide metabolic process; GO:0009142 nucleoside triphosphate biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0006812 cation transport; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:1990542 mitochondrial transmembrane transport; GO:1901135 carbohydrate derivative metabolic process; GO:1902600 hydrogen ion transmembrane transport; GO:0034641 cellular nitrogen compound metabolic process; GO:1902580 single-organism cellular localization; GO:0099132 ATP hydrolysis coupled cation transmembrane transport; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0099131 ATP hydrolysis coupled ion transmembrane transport; GO:0009987 cellular process; GO:0009119 ribonucleoside metabolic process; GO:0046034 ATP metabolic process; GO:0009124 nucleoside monophosphate biosynthetic process; GO:0044711 single-organism biosynthetic process; GO:0098660 inorganic ion transmembrane transport; GO:0009127 purine nucleoside monophosphate biosynthetic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0042455 ribonucleoside biosynthetic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0006163 purine nucleotide metabolic process; GO:0006818 hydrogen transport; GO:0015992 proton transport; GO:0051641 cellular localization; GO:0046128 purine ribonucleoside metabolic process; GO:0055085 transmembrane transport; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0009152 purine ribonucleotide biosynthetic process; GO:0006793 phosphorus metabolic process; GO:1901659 glycosyl compound biosynthetic process; GO:0006811 ion transport; GO:0009260 ribonucleotide biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0051179 localization; GO:0015672 monovalent inorganic cation transport; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044455 mitochondrial membrane part; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0005740 mitochondrial envelope; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain; GO:0005743 mitochondrial inner membrane; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o); GO:0005576 extracellular region; GO:0045259 proton-transporting ATP synthase complex; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005753 mitochondrial proton-transporting ATP synthase complex; GO:0016469 proton-transporting two-sector ATPase complex; GO:0031975 envelope; GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o); GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0015075 ion transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0015077 monovalent inorganic cation transmembrane transporter activity; GO:0022890 inorganic cation transmembrane transporter activity; GO:0015078 hydrogen ion transmembrane transporter activity; GO:0008324 cation transmembrane transporter activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; ","K02140","ATPeFG; F-type H+-transporting ATPase subunit g","hsa04714 Thermogenesis - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); "]
["O75976","Carboxypeptidase D OS=Homo sapiens OX=9606 GN=CPD","CPD",152.93,3.8842,1.5,3,3,3,0.957,0.992,0.892,1.094,1.067,1.003,1.114,0.056,"plasma membrane\r","GO:0006518 peptide metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0016485 protein processing; GO:0043603 cellular amide metabolic process; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0010467 gene expression; GO:0006508 proteolysis; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0051604 protein maturation; GO:0009987 cellular process; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0005623 cell; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0004180 carboxypeptidase activity; GO:0008233 peptidase activity; GO:0008238 exopeptidase activity; GO:0008236 serine-type peptidase activity; GO:0008235 metalloexopeptidase activity; GO:0043167 ion binding; GO:0016787 hydrolase activity; GO:0008237 metallopeptidase activity; GO:0070008 serine-type exopeptidase activity; GO:0008270 zinc ion binding; GO:0046914 transition metal ion binding; GO:0004181 metallocarboxypeptidase activity; GO:0017171 serine hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0004185 serine-type carboxypeptidase activity; ","K07752",null,null,"IPR008969; IPR000834; IPR034241; IPR014766; IPR034224; IPR033848; ","\"Carboxypeptidase-like, regulatory domain; Peptidase M14, carboxypeptidase A; Carboxypeptidase D,  carboxypeptidase-like domain 1; Carboxypeptidase, regulatory domain; Carboxypeptidase D,  carboxypeptidase-like domain 2; Carboxypeptidase D, carboxypeptidase-like domain 3; \"\r"]
["O76003","Glutaredoxin-3 OS=Homo sapiens OX=9606 GN=GLRX3","GLRX3",37.432,27.92,23,7,15,7,0.81,0.881,0.83,1.122,1.21,1.179,1.393,0.000579,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0044085 cellular component biogenesis; GO:0051188 cofactor biosynthetic process; GO:0016043 cellular component organization; GO:0065008 regulation of biological quality; GO:1903522 regulation of blood circulation; GO:0045454 cell redox homeostasis; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0008016 regulation of heart contraction; GO:0048519 negative regulation of biological process; GO:0044237 cellular metabolic process; GO:0051239 regulation of multicellular organismal process; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0008152 metabolic process; GO:0031163 metallo-sulfur cluster assembly; GO:0014743 regulation of muscle hypertrophy; GO:0022607 cellular component assembly; GO:0044057 regulation of system process; GO:0016226 iron-sulfur cluster assembly; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0009987 cellular process; GO:0006790 sulfur compound metabolic process; GO:0044571 [2Fe-2S] cluster assembly; GO:0055114 oxidation-reduction process; GO:0044763 single-organism cellular process; GO:0019725 cellular homeostasis; GO:0090257 regulation of muscle system process; GO:0014741 negative regulation of muscle hypertrophy; GO:0044238 primary metabolic process; GO:0044249 cellular biosynthetic process; GO:0010611 regulation of cardiac muscle hypertrophy; GO:0051186 cofactor metabolic process; GO:0097428 protein maturation by iron-sulfur cluster transfer; GO:0043502 regulation of muscle adaptation; GO:0050789 regulation of biological process; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:0010614 negative regulation of cardiac muscle hypertrophy; GO:0002026 regulation of the force of heart contraction; GO:0010467 gene expression; GO:0051604 protein maturation; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0030425 dendrite; GO:0044421 extracellular region part; GO:0005938 cell cortex; GO:0071944 cell periphery; GO:0030016 myofibril; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0099568 cytoplasmic region; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0030018 Z disc; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0031674 I band; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0043292 contractile fiber; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005576 extracellular region; GO:0099081 supramolecular polymer; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0036477 somatodendritic compartment; GO:0030017 sarcomere; GO:0044449 contractile fiber part; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0015035 protein disulfide oxidoreductase activity; GO:0003723 RNA binding; GO:0043167 ion binding; GO:0019901 protein kinase binding; GO:0005515 protein binding; GO:0019900 kinase binding; GO:0016491 oxidoreductase activity; GO:0015036 disulfide oxidoreductase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0009055 electron carrier activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0051536 iron-sulfur cluster binding; GO:0003676 nucleic acid binding; GO:0016667 oxidoreductase activity, acting on a sulfur group of donors; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005080 protein kinase C binding; GO:0019899 enzyme binding; GO:0051540 metal cluster binding; ",{"$nulls":3},"IPR002109; IPR033658; IPR013766; IPR012336; ","\"Glutaredoxin; Glutaredoxin, PICOT-like; Thioredoxin domain; Thioredoxin-like fold; \"\r"]
["O76021","Ribosomal L1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RSL1D1","RSL1D1",54.972,37.342,11.2,6,7,6,0.79,0.816,0.817,1.132,1.217,1.232,1.478,1.64E-4,"nucleus\r","GO:0050794 regulation of cellular process; GO:0044085 cellular component biogenesis; GO:0001649 osteoblast differentiation; GO:0044707 single-multicellular organism process; GO:0010941 regulation of cell death; GO:0022613 ribonucleoprotein complex biogenesis; GO:0006725 cellular aromatic compound metabolic process; GO:0090342 regulation of cell aging; GO:0048869 cellular developmental process; GO:0043067 regulation of programmed cell death; GO:0044699 single-organism process; GO:0080134 regulation of response to stress; GO:0044237 cellular metabolic process; GO:0042273 ribosomal large subunit biogenesis; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0032879 regulation of localization; GO:0006364 rRNA processing; GO:0000470 maturation of LSU-rRNA; GO:0034641 cellular nitrogen compound metabolic process; GO:0032880 regulation of protein localization; GO:0043170 macromolecule metabolic process; GO:2000772 regulation of cellular senescence; GO:0009987 cellular process; GO:0034470 ncRNA processing; GO:0006396 RNA processing; GO:0016072 rRNA metabolic process; GO:0032502 developmental process; GO:0001503 ossification; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0042254 ribosome biogenesis; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:0032501 multicellular organismal process; GO:0016070 RNA metabolic process; GO:0050789 regulation of biological process; GO:0080135 regulation of cellular response to stress; GO:0090304 nucleic acid metabolic process; GO:0044767 single-organism developmental process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0050793 regulation of developmental process; GO:0034660 ncRNA metabolic process; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005730 nucleolus; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0030684 preribosome; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0030686 90S preribosome; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0050839 cell adhesion molecule binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; ","K14775",null,null,"IPR023674; IPR016094; ","\"Ribosomal protein L1-like; Ribosomal protein L1, 2-layer alpha/beta-sandwich; \"\r"]
["O76024","Wolframin OS=Homo sapiens OX=9606 GN=WFS1","WFS1",100.29,9.6065,4.9,4,5,4,1.04,1.146,1.196,0.887,0.971,0.943,0.828,0.0189,"plasma membrane\r","GO:0044700 single organism signaling; GO:0051349 positive regulation of lyase activity; GO:0065008 regulation of biological quality; GO:0010941 regulation of cell death; GO:0032270 positive regulation of cellular protein metabolic process; GO:0007601 visual perception; GO:0042593 glucose homeostasis; GO:0009891 positive regulation of biosynthetic process; GO:0043523 regulation of neuron apoptotic process; GO:0036503 ERAD pathway; GO:0007635 chemosensory behavior; GO:1905897 regulation of response to endoplasmic reticulum stress; GO:0044237 cellular metabolic process; GO:0050877 neurological system process; GO:1904036 negative regulation of epithelial cell apoptotic process; GO:0009607 response to biotic stimulus; GO:0045927 positive regulation of growth; GO:0007610 behavior; GO:0030810 positive regulation of nucleotide biosynthetic process; GO:0008152 metabolic process; GO:0035966 response to topologically incorrect protein; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0055065 metal ion homeostasis; GO:0010562 positive regulation of phosphorus metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0042048 olfactory behavior; GO:1900373 positive regulation of purine nucleotide biosynthetic process; GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway; GO:0051716 cellular response to stimulus; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:0000122 negative regulation of transcription from RNA polymerase II promoter; GO:0043269 regulation of ion transport; GO:0044763 single-organism cellular process; GO:1900102 negative regulation of endoplasmic reticulum unfolded protein response; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0006874 cellular calcium ion homeostasis; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0051339 regulation of lyase activity; GO:0031279 regulation of cyclase activity; GO:1901575 organic substance catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:2000674 regulation of type B pancreatic cell apoptotic process; GO:0030104 water homeostasis; GO:1902532 negative regulation of intracellular signal transduction; GO:0080135 regulation of cellular response to stress; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0030163 protein catabolic process; GO:0051090 regulation of sequence-specific DNA binding transcription factor activity; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0045981 positive regulation of nucleotide metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0060548 negative regulation of cell death; GO:2000675 negative regulation of type B pancreatic cell apoptotic process; GO:0006140 regulation of nucleotide metabolic process; GO:0044708 single-organism behavior; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0033554 cellular response to stress; GO:0034976 response to endoplasmic reticulum stress; GO:0030801 positive regulation of cyclic nucleotide metabolic process; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0043067 regulation of programmed cell death; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:0045892 negative regulation of transcription, DNA-templated; GO:1900101 regulation of endoplasmic reticulum unfolded protein response; GO:0023057 negative regulation of signaling; GO:0045761 regulation of adenylate cyclase activity; GO:0043524 negative regulation of neuron apoptotic process; GO:0010648 negative regulation of cell communication; GO:0009889 regulation of biosynthetic process; GO:1903891 regulation of ATF6-mediated unfolded protein response; GO:0030817 regulation of cAMP biosynthetic process; GO:0010959 regulation of metal ion transport; GO:0044248 cellular catabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0033500 carbohydrate homeostasis; GO:0007275 multicellular organism development; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0009966 regulation of signal transduction; GO:0006983 ER overload response; GO:0048878 chemical homeostasis; GO:1904035 regulation of epithelial cell apoptotic process; GO:0051928 positive regulation of calcium ion transport; GO:1901215 negative regulation of neuron death; GO:0006986 response to unfolded protein; GO:0001822 kidney development; GO:1902531 regulation of intracellular signal transduction; GO:0006950 response to stress; GO:0048731 system development; GO:0003014 renal system process; GO:0051924 regulation of calcium ion transport; GO:0010033 response to organic substance; GO:0006984 ER-nucleus signaling pathway; GO:0044238 primary metabolic process; GO:0030799 regulation of cyclic nucleotide metabolic process; GO:0009892 negative regulation of metabolic process; GO:1903573 negative regulation of response to endoplasmic reticulum stress; GO:0043270 positive regulation of ion transport; GO:0009890 negative regulation of biosynthetic process; GO:0051247 positive regulation of protein metabolic process; GO:0031398 positive regulation of protein ubiquitination; GO:0006873 cellular ion homeostasis; GO:0050891 multicellular organismal water homeostasis; GO:0031325 positive regulation of cellular metabolic process; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0031647 regulation of protein stability; GO:0032469 endoplasmic reticulum calcium ion homeostasis; GO:0007605 sensory perception of sound; GO:0031328 positive regulation of cellular biosynthetic process; GO:0050821 protein stabilization; GO:0072503 cellular divalent inorganic cation homeostasis; GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0051253 negative regulation of RNA metabolic process; GO:0030819 positive regulation of cAMP biosynthetic process; GO:0048871 multicellular organismal homeostasis; GO:0030968 endoplasmic reticulum unfolded protein response; GO:0031396 regulation of protein ubiquitination; GO:0006457 protein folding; GO:2001141 regulation of RNA biosynthetic process; GO:2001233 regulation of apoptotic signaling pathway; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0030433 ubiquitin-dependent ERAD pathway; GO:2001243 negative regulation of intrinsic apoptotic signaling pathway; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0030814 regulation of cAMP metabolic process; GO:0070887 cellular response to chemical stimulus; GO:0030808 regulation of nucleotide biosynthetic process; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0003091 renal water homeostasis; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0007600 sensory perception; GO:0030802 regulation of cyclic nucleotide biosynthetic process; GO:0045937 positive regulation of phosphate metabolic process; GO:0050801 ion homeostasis; GO:0031326 regulation of cellular biosynthetic process; GO:0055074 calcium ion homeostasis; GO:0030816 positive regulation of cAMP metabolic process; GO:0098771 inorganic ion homeostasis; GO:0019725 cellular homeostasis; GO:0048522 positive regulation of cellular process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051050 positive regulation of transport; GO:0001655 urogenital system development; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:1900371 regulation of purine nucleotide biosynthetic process; GO:0045762 positive regulation of adenylate cyclase activity; GO:1902679 negative regulation of RNA biosynthetic process; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0030804 positive regulation of cyclic nucleotide biosynthetic process; GO:0072507 divalent inorganic cation homeostasis; GO:0048856 anatomical structure development; GO:0050954 sensory perception of mechanical stimulus; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0043069 negative regulation of programmed cell death; GO:0040008 regulation of growth; GO:0044257 cellular protein catabolic process; GO:0035967 cellular response to topologically incorrect protein; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:1903892 negative regulation of ATF6-mediated unfolded protein response; GO:0060255 regulation of macromolecule metabolic process; GO:0030003 cellular cation homeostasis; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0071310 cellular response to organic substance; GO:0072001 renal system development; GO:0036498 IRE1-mediated unfolded protein response; GO:1900544 positive regulation of purine nucleotide metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0055082 cellular chemical homeostasis; GO:0010498 proteasomal protein catabolic process; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:1903322 positive regulation of protein modification by small protein conjugation or removal; GO:0071216 cellular response to biotic stimulus; GO:0055080 cation homeostasis; GO:0043066 negative regulation of apoptotic process; GO:0006508 proteolysis; GO:1902235 regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway; GO:0009987 cellular process; GO:1901214 regulation of neuron death; GO:0043632 modification-dependent macromolecule catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0050878 regulation of body fluid levels; GO:0003008 system process; GO:0006355 regulation of transcription, DNA-templated; GO:0034620 cellular response to unfolded protein; GO:0010629 negative regulation of gene expression; GO:0022417 protein maturation by protein folding; GO:0019941 modification-dependent protein catabolic process; GO:0051049 regulation of transport; GO:0044712 single-organism catabolic process; GO:0031401 positive regulation of protein modification process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0050953 sensory perception of light stimulus; GO:0048585 negative regulation of response to stimulus; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:1900542 regulation of purine nucleotide metabolic process; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0031281 positive regulation of cyclase activity; GO:2001242 regulation of intrinsic apoptotic signaling pathway; GO:0009057 macromolecule catabolic process; GO:0031016 pancreas development; GO:0006875 cellular metal ion homeostasis; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0010467 gene expression; GO:0031327 negative regulation of cellular biosynthetic process; GO:0051604 protein maturation; GO:0009056 catabolic process; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0030425 dendrite; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:1905369 endopeptidase complex; GO:1902494 catalytic complex; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0031227 intrinsic component of endoplasmic reticulum membrane; GO:0043005 neuron projection; GO:1905368 peptidase complex; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0005789 endoplasmic reticulum membrane; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0000502 proteasome complex; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0016021 integral component of membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0036477 somatodendritic compartment; GO:0044432 endoplasmic reticulum part; GO:0030176 integral component of endoplasmic reticulum membrane; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0031625 ubiquitin protein ligase binding; GO:0051117 ATPase binding; GO:0005488 binding; GO:0005515 protein binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0005516 calmodulin binding; GO:0048306 calcium-dependent protein binding; GO:0033613 activating transcription factor binding; GO:0019899 enzyme binding; GO:0008134 transcription factor binding; ","K14020","WFS1; wolfamin","hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); ","IPR011990; ","Tetratricopeptide-like helical domain; \r"]
["O76041","Nebulette OS=Homo sapiens OX=9606 GN=NEBL","NEBL",116.45,4.678,2.2,2,4,2,1.294,1.136,1.03,0.833,0.818,0.92,0.743,0.0176,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0055001 muscle cell development; GO:0072359 circulatory system development; GO:0014706 striated muscle tissue development; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0055006 cardiac cell development; GO:0071691 cardiac muscle thin filament assembly; GO:0048738 cardiac muscle tissue development; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0007015 actin filament organization; GO:0032989 cellular component morphogenesis; GO:0048468 cell development; GO:0055007 cardiac muscle cell differentiation; GO:0009653 anatomical structure morphogenesis; GO:0030036 actin cytoskeleton organization; GO:0030154 cell differentiation; GO:0007507 heart development; GO:0022607 cellular component assembly; GO:0070925 organelle assembly; GO:0030239 myofibril assembly; GO:0061061 muscle structure development; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0055013 cardiac muscle cell development; GO:0055003 cardiac myofibril assembly; GO:0032502 developmental process; GO:0031032 actomyosin structure organization; GO:0051146 striated muscle cell differentiation; GO:0035051 cardiocyte differentiation; GO:0009888 tissue development; GO:0048731 system development; GO:0060537 muscle tissue development; GO:0010927 cellular component assembly involved in morphogenesis; GO:0044763 single-organism cellular process; GO:0032501 multicellular organismal process; GO:1902589 single-organism organelle organization; GO:0048513 animal organ development; GO:0055002 striated muscle cell development; GO:0044767 single-organism developmental process; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0042692 muscle cell differentiation; GO:0048856 anatomical structure development; GO:0097435 supramolecular fiber organization; GO:0071840 cellular component organization or biogenesis; ","GO:0044421 extracellular region part; GO:0030016 myofibril; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0030018 Z disc; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0031674 I band; GO:0044422 organelle part; GO:0032432 actin filament bundle; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:0043292 contractile fiber; GO:1903561 extracellular vesicle; GO:0001725 stress fiber; GO:0043227 membrane-bounded organelle; GO:0042641 actomyosin; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0097517 contractile actin filament bundle; GO:0005576 extracellular region; GO:0015629 actin cytoskeleton; GO:0099081 supramolecular polymer; GO:0043226 organelle; GO:0030017 sarcomere; GO:0044449 contractile fiber part; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0051015 actin filament binding; GO:0008092 cytoskeletal protein binding; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0003779 actin binding; GO:0005523 tropomyosin binding; GO:0005515 protein binding; GO:0008307 structural constituent of muscle; GO:0005198 structural molecule activity; GO:0031005 filamin binding; GO:0032403 protein complex binding; ",{"$nulls":3},"IPR001452; ","SH3 domain; \r"]
["O76070","Gamma-synuclein OS=Homo sapiens OX=9606 GN=SNCG","SNCG",13.331,50.774,63.8,6,8,6,1.115,1.122,1.211,0.923,0.827,0.928,0.777,5.28E-3,"cytoplasm\r","GO:0044700 single organism signaling; GO:0050794 regulation of cellular process; GO:0001505 regulation of neurotransmitter levels; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0065008 regulation of biological quality; GO:0008344 adult locomotory behavior; GO:0014059 regulation of dopamine secretion; GO:0023051 regulation of signaling; GO:0051046 regulation of secretion; GO:0044699 single-organism process; GO:0015031 protein transport; GO:0060341 regulation of cellular localization; GO:0051234 establishment of localization; GO:0007610 behavior; GO:0050433 regulation of catecholamine secretion; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:1902578 single-organism localization; GO:0051952 regulation of amine transport; GO:0032879 regulation of localization; GO:0099537 trans-synaptic signaling; GO:0009306 protein secretion; GO:0098916 anterograde trans-synaptic signaling; GO:0051588 regulation of neurotransmitter transport; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0030534 adult behavior; GO:0009987 cellular process; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0051049 regulation of transport; GO:0050804 modulation of synaptic transmission; GO:0043269 regulation of ion transport; GO:0044763 single-organism cellular process; GO:0071702 organic substance transport; GO:0023052 signaling; GO:1903530 regulation of secretion by cell; GO:0046928 regulation of neurotransmitter secretion; GO:0050808 synapse organization; GO:0032501 multicellular organismal process; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0007267 cell-cell signaling; GO:0099536 synaptic signaling; GO:0032940 secretion by cell; GO:0007626 locomotory behavior; GO:0007268 chemical synaptic transmission; GO:0051179 localization; GO:0044708 single-organism behavior; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0043025 neuronal cell body; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0005815 microtubule organizing center; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0005576 extracellular region; GO:0005819 spindle; GO:0030424 axon; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0044297 cell body; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; "]
["O76071","Probable cytosolic iron-sulfur protein assembly protein CIAO1 OS=Homo sapiens OX=9606 GN=CIAO1","CIAO1",37.84,39.073,8,2,3,2,1.114,1.003,1.009,0.966,1.01,0.915,0.925,0.155,"nucleus\r","GO:0050794 regulation of cellular process; GO:0044085 cellular component biogenesis; GO:0051188 cofactor biosynthetic process; GO:0016043 cellular component organization; GO:0042127 regulation of cell proliferation; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0031163 metallo-sulfur cluster assembly; GO:0008152 metabolic process; GO:0022607 cellular component assembly; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0016226 iron-sulfur cluster assembly; GO:0009987 cellular process; GO:0006790 sulfur compound metabolic process; GO:0010468 regulation of gene expression; GO:0007059 chromosome segregation; GO:0006355 regulation of transcription, DNA-templated; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0051186 cofactor metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0019222 regulation of metabolic process; GO:0008284 positive regulation of cell proliferation; GO:0065007 biological regulation; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005819 spindle; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0005856 cytoskeleton; GO:0015630 microtubule cytoskeleton; GO:0044464 cell part; GO:0005622 intracellular; GO:0044445 cytosolic part; GO:0071817 MMXD complex; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0097361 CIA complex; ","GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR017986; IPR015943; ","WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain; \r"]
["O76076","WNT1-inducible-signaling pathway protein 2 OS=Homo sapiens OX=9606 GN=WISP2","WISP2",26.825,32.317,15.6,2,2,2,1.18,1.04,1.059,0.879,0.988,0.873,0.836,0.0332,"extracellular\r","GO:0044700 single organism signaling; GO:0050794 regulation of cellular process; GO:0051716 cellular response to stimulus; GO:0040008 regulation of growth; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0023052 signaling; GO:0050896 response to stimulus; GO:0001558 regulation of cell growth; GO:0022610 biological adhesion; GO:0007165 signal transduction; GO:0050789 regulation of biological process; GO:0007154 cell communication; GO:0007267 cell-cell signaling; GO:0007155 cell adhesion; GO:0051128 regulation of cellular component organization; GO:0009987 cellular process; GO:0065007 biological regulation; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:0005520 insulin-like growth factor binding; GO:0005515 protein binding; GO:0019838 growth factor binding; GO:0005488 binding; ",{"$nulls":3},"IPR001007; IPR000867; IPR009030; ","\"VWFC domain; Insulin-like growth factor-binding protein, IGFBP; Growth factor receptor cysteine-rich domain; \"\r"]
["O76094","Signal recognition particle subunit SRP72 OS=Homo sapiens OX=9606 GN=SRP72","SRP72",74.605,61.825,18.2,11,15,11,0.875,0.911,0.952,1.102,1.062,1.092,1.189,0.0029,"cyto_nucl\r","GO:0046907 intracellular transport; GO:0072594 establishment of protein localization to organelle; GO:0006613 cotranslational protein targeting to membrane; GO:0050896 response to stimulus; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0042493 response to drug; GO:0051649 establishment of localization in cell; GO:0070972 protein localization to endoplasmic reticulum; GO:0065002 intracellular protein transmembrane transport; GO:0006886 intracellular protein transport; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0033365 protein localization to organelle; GO:0034613 cellular protein localization; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0090150 establishment of protein localization to membrane; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation; GO:0072657 protein localization to membrane; GO:0071806 protein transmembrane transport; GO:0045047 protein targeting to ER; GO:0071702 organic substance transport; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:0055085 transmembrane transport; GO:0070727 cellular macromolecule localization; GO:0042221 response to chemical; GO:0051179 localization; ","GO:0043229 intracellular organelle; GO:0005783 endoplasmic reticulum; GO:0048500 signal recognition particle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005786 signal recognition particle, endoplasmic reticulum targeting; GO:0005622 intracellular; GO:0044464 cell part; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005047 signal recognition particle binding; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0043021 ribonucleoprotein complex binding; GO:0008312 7S RNA binding; ","K03108","SRP72; signal recognition particle subunit SRP72","hsa03060 Protein export - Homo sapiens (human); ","IPR011990; IPR013699; IPR013026; ","\"Tetratricopeptide-like helical domain; Signal recognition particle, SRP72 subunit, RNA-binding; Tetratricopeptide repeat-containing domain; \"\r"]
["O94760","N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 OS=Homo sapiens OX=9606 GN=DDAH1","DDAH1",31.121,33.401,29.1,8,12,7,1.013,1.058,1.131,1.03,0.891,0.895,0.879,0.0866,"cytoplasm\r","GO:0044700 single organism signaling; GO:1901606 alpha-amino acid catabolic process; GO:0065008 regulation of biological quality; GO:0045428 regulation of nitric oxide biosynthetic process; GO:0009891 positive regulation of biosynthetic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0006520 cellular amino acid metabolic process; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:1904018 positive regulation of vasculature development; GO:0003073 regulation of systemic arterial blood pressure; GO:0045429 positive regulation of nitric oxide biosynthetic process; GO:0051716 cellular response to stimulus; GO:0031326 regulation of cellular biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006525 arginine metabolic process; GO:0048522 positive regulation of cellular process; GO:0019932 second-messenger-mediated signaling; GO:0031323 regulation of cellular metabolic process; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0051341 regulation of oxidoreductase activity; GO:0046395 carboxylic acid catabolic process; GO:1901575 organic substance catabolic process; GO:0050789 regulation of biological process; GO:0032768 regulation of monooxygenase activity; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0009065 glutamine family amino acid catabolic process; GO:1904407 positive regulation of nitric oxide metabolic process; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0009063 cellular amino acid catabolic process; GO:0045765 regulation of angiogenesis; GO:0006082 organic acid metabolic process; GO:0003013 circulatory system process; GO:2000377 regulation of reactive oxygen species metabolic process; GO:0051094 positive regulation of developmental process; GO:0050999 regulation of nitric-oxide synthase activity; GO:0000052 citrulline metabolic process; GO:0043436 oxoacid metabolic process; GO:2000026 regulation of multicellular organismal development; GO:0050794 regulation of cellular process; GO:0008217 regulation of blood pressure; GO:1903428 positive regulation of reactive oxygen species biosynthetic process; GO:0007263 nitric oxide mediated signal transduction; GO:0050896 response to stimulus; GO:0045766 positive regulation of angiogenesis; GO:0051239 regulation of multicellular organismal process; GO:0071704 organic substance metabolic process; GO:0009889 regulation of biosynthetic process; GO:0008015 blood circulation; GO:0044248 cellular catabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0009987 cellular process; GO:0009064 glutamine family amino acid metabolic process; GO:0003008 system process; GO:0035556 intracellular signal transduction; GO:0044712 single-organism catabolic process; GO:1903426 regulation of reactive oxygen species biosynthetic process; GO:1901342 regulation of vasculature development; GO:0006807 nitrogen compound metabolic process; GO:0044282 small molecule catabolic process; GO:1901605 alpha-amino acid metabolic process; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:2000379 positive regulation of reactive oxygen species metabolic process; GO:1901565 organonitrogen compound catabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0016054 organic acid catabolic process; GO:0019752 carboxylic acid metabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0009056 catabolic process; GO:0050793 regulation of developmental process; GO:0006527 arginine catabolic process; GO:0065007 biological regulation; GO:1901564 organonitrogen compound metabolic process; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016597 amino acid binding; GO:0031406 carboxylic acid binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines; GO:0043167 ion binding; GO:0043177 organic acid binding; GO:0016403 dimethylargininase activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0016787 hydrolase activity; GO:0043168 anion binding; GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; GO:0036094 small molecule binding; ","K01482"]
["O94776","Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2","MTA2",75.022,18.269,12.6,8,8,7,0.959,0.961,0.947,1.11,0.981,1.095,1.111,0.118,"cytoplasm\r","GO:0010762 regulation of fibroblast migration; GO:0023051 regulation of signaling; GO:0009891 positive regulation of biosynthetic process; GO:0044237 cellular metabolic process; GO:0051253 negative regulation of RNA metabolic process; GO:0032259 methylation; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0010646 regulation of cell communication; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0032879 regulation of localization; GO:0019538 protein metabolic process; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0043170 macromolecule metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0098732 macromolecule deacylation; GO:0006476 protein deacetylation; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0006333 chromatin assembly or disassembly; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0000122 negative regulation of transcription from RNA polymerase II promoter; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0043044 ATP-dependent chromatin remodeling; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0035601 protein deacylation; GO:0006306 DNA methylation; GO:0048583 regulation of response to stimulus; GO:1902679 negative regulation of RNA biosynthetic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006464 cellular protein modification process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0006325 chromatin organization; GO:0036211 protein modification process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0006305 DNA alkylation; GO:0006338 chromatin remodeling; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0006259 DNA metabolic process; GO:0016570 histone modification; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0071704 organic substance metabolic process; GO:0045892 negative regulation of transcription, DNA-templated; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:2000145 regulation of cell motility; GO:1901796 regulation of signal transduction by p53 class mediator; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0016569 covalent chromatin modification; GO:0009966 regulation of signal transduction; GO:0006304 DNA modification; GO:0009987 cellular process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0016575 histone deacetylation; GO:0051254 positive regulation of RNA metabolic process; GO:1902531 regulation of intracellular signal transduction; GO:0006355 regulation of transcription, DNA-templated; GO:0051270 regulation of cellular component movement; GO:0010629 negative regulation of gene expression; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0006807 nitrogen compound metabolic process; GO:0030334 regulation of cell migration; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0009892 negative regulation of metabolic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0009890 negative regulation of biosynthetic process; GO:0051276 chromosome organization; GO:0006996 organelle organization; GO:0043414 macromolecule methylation; GO:0031325 positive regulation of cellular metabolic process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0043412 macromolecule modification; GO:0040012 regulation of locomotion; GO:0044728 DNA methylation or demethylation; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0032991 macromolecular complex; GO:0017053 transcriptional repressor complex; GO:0044424 intracellular part; GO:0070603 SWI/SNF superfamily-type complex; GO:0005623 cell; GO:0044422 organelle part; GO:0000118 histone deacetylase complex; GO:0090568 nuclear transcriptional repressor complex; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0044454 nuclear chromosome part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0090545 CHD-type complex; GO:0000790 nuclear chromatin; GO:0016581 NuRD complex; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005667 transcription factor complex; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0000785 chromatin; GO:0000228 nuclear chromosome; GO:0043234 protein complex; GO:0044428 nuclear part; ","GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0003682 chromatin binding; GO:0003700 transcription factor activity, sequence-specific DNA binding; GO:0000975 regulatory region DNA binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0042826 histone deacetylase binding; GO:0070491 repressing transcription factor binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0001085 RNA polymerase II transcription factor binding; GO:0001071 nucleic acid binding transcription factor activity; GO:0000989 transcription factor activity, transcription factor binding; GO:0043169 cation binding; GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; GO:0003677 DNA binding; GO:0001103 RNA polymerase II repressing transcription factor binding; GO:0043167 ion binding; GO:0043565 sequence-specific DNA binding; GO:0008270 zinc ion binding; GO:0004407 histone deacetylase activity; GO:0001067 regulatory region nucleic acid binding; GO:0046914 transition metal ion binding; GO:0033558 protein deacetylase activity; GO:0044212 transcription regulatory region DNA binding; GO:0003676 nucleic acid binding; GO:0046872 metal ion binding; GO:0019213 deacetylase activity; GO:0000988 transcription factor activity, protein binding; GO:0008134 transcription factor binding; GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; GO:0019899 enzyme binding; ","K11660",null,null,"IPR001005; IPR000949; IPR009057; IPR001025; IPR017884; IPR000679; ","\"SANT/Myb domain; ELM2 domain; Homeobox domain-like; Bromo adjacent homology (BAH) domain; SANT domain; Zinc finger, GATA-type; \"\r"]
["O94811","Tubulin polymerization-promoting protein OS=Homo sapiens OX=9606 GN=TPPP","TPPP",23.693,5.0656,11.9,3,3,3,1.01,1.097,0.951,0.998,1.096,0.863,0.967,0.674,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0032273 positive regulation of protein polymerization; GO:0031109 microtubule polymerization or depolymerization; GO:0044699 single-organism process; GO:0044087 regulation of cellular component biogenesis; GO:0051130 positive regulation of cellular component organization; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0032271 regulation of protein polymerization; GO:0031334 positive regulation of protein complex assembly; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0043623 cellular protein complex assembly; GO:0034622 cellular macromolecular complex assembly; GO:0071822 protein complex subunit organization; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0048518 positive regulation of biological process; GO:0007017 microtubule-based process; GO:0043933 macromolecular complex subunit organization; GO:1902589 single-organism organelle organization; GO:0000226 microtubule cytoskeleton organization; GO:0050789 regulation of biological process; GO:0043254 regulation of protein complex assembly; GO:0006996 organelle organization; GO:0051258 protein polymerization; GO:0051128 regulation of cellular component organization; GO:0070271 protein complex biogenesis; GO:0046785 microtubule polymerization; GO:0097435 supramolecular fiber organization; GO:0001578 microtubule bundle formation; GO:0044089 positive regulation of cellular component biogenesis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0005874 microtubule; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0099081 supramolecular polymer; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0005856 cytoskeleton; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0015630 microtubule cytoskeleton; GO:0043209 myelin sheath; GO:0005622 intracellular; GO:0044464 cell part; GO:0048471 perinuclear region of cytoplasm; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0015631 tubulin binding; GO:0005515 protein binding; GO:0008092 cytoskeletal protein binding; GO:0008017 microtubule binding; GO:0005488 binding; ",{"$nulls":3},"IPR011992; ","EF-hand domain pair; \r"]
["O94826","Mitochondrial import receptor subunit TOM70 OS=Homo sapiens OX=9606 GN=TOMM70","TOMM70",67.454,65.893,24.2,15,20,15,0.917,0.99,0.91,1.033,1.083,1.012,1.11,0.0352,"E.R._mito\r","GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0072594 establishment of protein localization to organelle; GO:0006839 mitochondrial transport; GO:0006914 autophagy; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0007005 mitochondrion organization; GO:0006886 intracellular protein transport; GO:0044248 cellular catabolic process; GO:0006626 protein targeting to mitochondrion; GO:0033365 protein localization to organelle; GO:0034613 cellular protein localization; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0009987 cellular process; GO:0016236 macroautophagy; GO:0071806 protein transmembrane transport; GO:0071702 organic substance transport; GO:0070585 protein localization to mitochondrion; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:0055085 transmembrane transport; GO:0070727 cellular macromolecule localization; GO:0006996 organelle organization; GO:0051179 localization; GO:0009056 catabolic process; GO:0072655 establishment of protein localization to mitochondrion; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0019867 outer membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0032991 macromolecular complex; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0031968 organelle outer membrane; GO:0005742 mitochondrial outer membrane translocase complex; GO:0043227 membrane-bounded organelle; GO:0098799 outer mitochondrial membrane protein complex; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0044429 mitochondrial part; GO:0005741 mitochondrial outer membrane; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031975 envelope; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0008565 protein transporter activity; GO:0022884 macromolecule transmembrane transporter activity; GO:0005488 binding; GO:0022892 substrate-specific transporter activity; GO:0008320 protein transmembrane transporter activity; GO:0005515 protein binding; GO:0022891 substrate-specific transmembrane transporter activity; GO:0022857 transmembrane transporter activity; GO:0005215 transporter activity; ","K17768",null,null,"IPR011990; IPR013026; ","Tetratricopeptide-like helical domain; Tetratricopeptide repeat-containing domain; \r"]
["O94832","Unconventional myosin-Id OS=Homo sapiens OX=9606 GN=MYO1D","MYO1D",116.2,115.32,22.6,22,28,22,0.992,1.02,0.985,1.027,1.021,1.007,1.019,0.188,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0046907 intracellular transport; GO:0007420 brain development; GO:0044699 single-organism process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0010923 negative regulation of phosphatase activity; GO:0051346 negative regulation of hydrolase activity; GO:0051234 establishment of localization; GO:0098927 vesicle-mediated transport between endosomal compartments; GO:0051649 establishment of localization in cell; GO:0035303 regulation of dephosphorylation; GO:0030900 forebrain development; GO:0060322 head development; GO:0007275 multicellular organism development; GO:0016482 cytosolic transport; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0061502 early endosome to recycling endosome transport; GO:0035305 negative regulation of dephosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0010921 regulation of phosphatase activity; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0009892 negative regulation of metabolic process; GO:0051641 cellular localization; GO:0006810 transport; GO:0016197 endosomal transport; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:0044767 single-organism developmental process; GO:0007417 central nervous system development; GO:0050790 regulation of catalytic activity; GO:0010563 negative regulation of phosphorus metabolic process; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0051179 localization; GO:0048856 anatomical structure development; GO:0045936 negative regulation of phosphate metabolic process; GO:0065007 biological regulation; ","GO:0030425 dendrite; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0098862 cluster of actin-based cell projections; GO:0098857 membrane microdomain; GO:0005737 cytoplasm; GO:0043025 neuronal cell body; GO:0032991 macromolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0032589 neuron projection membrane; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0098590 plasma membrane region; GO:0031256 leading edge membrane; GO:0043209 myelin sheath; GO:0005622 intracellular; GO:0030673 axolemma; GO:0098589 membrane region; GO:0043005 neuron projection; GO:0016459 myosin complex; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0031252 cell leading edge; GO:0042995 cell projection; GO:0044430 cytoskeletal part; GO:0005576 extracellular region; GO:0033267 axon part; GO:0005886 plasma membrane; GO:0030424 axon; GO:0043231 intracellular membrane-bounded organelle; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0016323 basolateral plasma membrane; GO:0005790 smooth endoplasmic reticulum; GO:0005783 endoplasmic reticulum; GO:0005903 brush border; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005856 cytoskeleton; GO:0044425 membrane part; GO:0044464 cell part; GO:0044304 main axon; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0045121 membrane raft; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0015629 actin cytoskeleton; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0044459 plasma membrane part; GO:0044853 plasma membrane raft; GO:0097440 apical dendrite; GO:0031253 cell projection membrane; GO:0044297 cell body; GO:0044444 cytoplasmic part; ","GO:0051015 actin filament binding; GO:0003774 motor activity; GO:1901265 nucleoside phosphate binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0048306 calcium-dependent protein binding; GO:0016887 ATPase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0008092 cytoskeletal protein binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0000146 microfilament motor activity; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0030898 actin-dependent ATPase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0005516 calmodulin binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0042623 ATPase activity, coupled; GO:0003779 actin binding; GO:0019904 protein domain specific binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0032403 protein complex binding; GO:0036094 small molecule binding; ","K10356",null,null,"IPR010926; IPR027417; IPR001609; ","\"Class I myosin tail homology domain; P-loop containing nucleoside triphosphate hydrolase; Myosin head, motor domain; \"\r"]
["O94855","Protein transport protein Sec24D OS=Homo sapiens OX=9606 GN=SEC24D","SEC24D",113.01,23.647,6.8,6,6,5,1.151,1.132,1.149,0.884,0.816,0.826,0.736,0.000275,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0051640 organelle localization; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0006901 vesicle coating; GO:0046907 intracellular transport; GO:0048207 vesicle targeting, rough ER to cis-Golgi; GO:0048208 COPII vesicle coating; GO:0043009 chordate embryonic development; GO:0044699 single-organism process; GO:0048193 Golgi vesicle transport; GO:0006903 vesicle targeting; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0051649 establishment of localization in cell; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0051648 vesicle localization; GO:0048199 vesicle targeting, to, from or within Golgi; GO:0006886 intracellular protein transport; GO:0007275 multicellular organism development; GO:0034613 cellular protein localization; GO:0009790 embryo development; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0032502 developmental process; GO:0051650 establishment of vesicle localization; GO:0071822 protein complex subunit organization; GO:0090114 COPII-coated vesicle budding; GO:0009792 embryo development ending in birth or egg hatching; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:0048002 antigen processing and presentation of peptide antigen; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0016050 vesicle organization; GO:0071702 organic substance transport; GO:0002376 immune system process; GO:0051656 establishment of organelle localization; GO:0002495 antigen processing and presentation of peptide antigen via MHC class II; GO:0032501 multicellular organismal process; GO:0043933 macromolecular complex subunit organization; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0019882 antigen processing and presentation; GO:0070727 cellular macromolecule localization; GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; GO:0001701 in utero embryonic development; GO:0044767 single-organism developmental process; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0006900 membrane budding; GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II; GO:0051179 localization; GO:0070271 protein complex biogenesis; GO:0048856 anatomical structure development; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0071840 cellular component organization or biogenesis; ","GO:0030658 transport vesicle membrane; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0030120 vesicle coat; GO:0005623 cell; GO:0030662 coated vesicle membrane; GO:0044422 organelle part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0048471 perinuclear region of cytoplasm; GO:0044431 Golgi apparatus part; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0012507 ER to Golgi transport vesicle membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0048475 coated membrane; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012506 vesicle membrane; GO:0030134 ER to Golgi transport vesicle; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0030135 coated vesicle; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044432 endoplasmic reticulum part; GO:0030117 membrane coat; GO:0030127 COPII vesicle coat; GO:0043234 protein complex; GO:0030133 transport vesicle; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0008270 zinc ion binding; GO:0046914 transition metal ion binding; GO:0005488 binding; GO:0043167 ion binding; ","K14007","SEC24; protein transport protein SEC24","hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); ","IPR006900; IPR012990; IPR006896; IPR006895; IPR029006; IPR007123; IPR002035; ","\"Sec23/Sec24, helical domain; Sec23/Sec24 beta-sandwich; Sec23/Sec24, trunk domain; Zinc finger, Sec23/Sec24-type; ADF-H/Gelsolin-like domain; Gelsolin-like domain; von Willebrand factor, type A; \"\r"]
["O94874","E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1","UFL1",89.594,43.535,12.2,9,9,9,0.967,1.002,0.993,0.991,1.02,1.026,1.025,0.174,"nucleus\r","GO:0001649 osteoblast differentiation; GO:0010941 regulation of cell death; GO:0014013 regulation of gliogenesis; GO:0044237 cellular metabolic process; GO:0032088 negative regulation of NF-kappaB transcription factor activity; GO:0008152 metabolic process; GO:0071569 protein ufmylation; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0009719 response to endogenous stimulus; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:1903362 regulation of cellular protein catabolic process; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0001503 ossification; GO:0048699 generation of neurons; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0010243 response to organonitrogen compound; GO:0060251 regulation of glial cell proliferation; GO:0051090 regulation of sequence-specific DNA binding transcription factor activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0048583 regulation of response to stimulus; GO:0061136 regulation of proteasomal protein catabolic process; GO:1901698 response to nitrogen compound; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0060548 negative regulation of cell death; GO:0051094 positive regulation of developmental process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0033554 cellular response to stress; GO:0034976 response to endoplasmic reticulum stress; GO:0042127 regulation of cell proliferation; GO:0031399 regulation of protein modification process; GO:0043067 regulation of programmed cell death; GO:1901700 response to oxygen-containing compound; GO:0044267 cellular protein metabolic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0045597 positive regulation of cell differentiation; GO:0051239 regulation of multicellular organismal process; GO:1990592 protein K69-linked ufmylation; GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0032880 regulation of protein localization; GO:0042176 regulation of protein catabolic process; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:0006950 response to stress; GO:0048731 system development; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0010033 response to organic substance; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1903321 negative regulation of protein modification by small protein conjugation or removal; GO:0032446 protein modification by small protein conjugation; GO:0050769 positive regulation of neurogenesis; GO:0043412 macromolecule modification; GO:0050793 regulation of developmental process; GO:0008284 positive regulation of cell proliferation; GO:0001101 response to acid chemical; GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0031400 negative regulation of protein modification process; GO:0031396 regulation of protein ubiquitination; GO:2001141 regulation of RNA biosynthetic process; GO:0010646 regulation of cell communication; GO:0010720 positive regulation of cell development; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0043200 response to amino acid; GO:0031326 regulation of cellular biosynthetic process; GO:0051962 positive regulation of nervous system development; GO:0048522 positive regulation of cellular process; GO:0070647 protein modification by small protein conjugation or removal; GO:0010605 negative regulation of macromolecule metabolic process; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0042221 response to chemical; GO:1902065 response to L-glutamate; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0036211 protein modification process; GO:0033143 regulation of intracellular steroid hormone receptor signaling pathway; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0060252 positive regulation of glial cell proliferation; GO:0043069 negative regulation of programmed cell death; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0043066 negative regulation of apoptotic process; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0031397 negative regulation of protein ubiquitination; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0014015 positive regulation of gliogenesis; GO:0033146 regulation of intracellular estrogen receptor signaling pathway; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:1990564 protein polyufmylation; GO:0051248 negative regulation of protein metabolic process; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; GO:0050767 regulation of neurogenesis; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0042995 cell projection; GO:0005783 endoplasmic reticulum; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044432 endoplasmic reticulum part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0043005 neuron projection; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0071568 UFM1 transferase activity; GO:0019787 ubiquitin-like protein transferase activity; GO:0016740 transferase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016874 ligase activity; "]
["O94875","Sorbin and SH3 domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SORBS2","SORBS2",124.11,53.172,7.3,6,9,6,1.126,1.257,1.095,0.936,0.92,0.736,0.745,0.0277,"nucleus\r","GO:0014706 striated muscle tissue development; GO:0072359 circulatory system development; GO:0055001 muscle cell development; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0016477 cell migration; GO:0003012 muscle system process; GO:0055006 cardiac cell development; GO:0048738 cardiac muscle tissue development; GO:0051674 localization of cell; GO:0048869 cellular developmental process; GO:0007015 actin filament organization; GO:0044699 single-organism process; GO:0048468 cell development; GO:0035265 organ growth; GO:0022610 biological adhesion; GO:0055007 cardiac muscle cell differentiation; GO:0030154 cell differentiation; GO:0030036 actin cytoskeleton organization; GO:0007507 heart development; GO:0003298 physiological muscle hypertrophy; GO:0003300 cardiac muscle hypertrophy; GO:0007155 cell adhesion; GO:0061061 muscle structure development; GO:0007275 multicellular organism development; GO:0055017 cardiac muscle tissue growth; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0055013 cardiac muscle cell development; GO:0032502 developmental process; GO:0051146 striated muscle cell differentiation; GO:0009888 tissue development; GO:0003008 system process; GO:0035051 cardiocyte differentiation; GO:0048731 system development; GO:0060537 muscle tissue development; GO:0016049 cell growth; GO:0044763 single-organism cellular process; GO:0048870 cell motility; GO:0032501 multicellular organismal process; GO:1902589 single-organism organelle organization; GO:0048513 animal organ development; GO:0014896 muscle hypertrophy; GO:0055002 striated muscle cell development; GO:0048588 developmental cell growth; GO:0044767 single-organism developmental process; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0061049 cell growth involved in cardiac muscle cell development; GO:0042692 muscle cell differentiation; GO:0006928 movement of cell or subcellular component; GO:0003301 physiological cardiac muscle hypertrophy; GO:0040011 locomotion; GO:0048589 developmental growth; GO:0051179 localization; GO:0040007 growth; GO:0048856 anatomical structure development; GO:0097435 supramolecular fiber organization; GO:0014897 striated muscle hypertrophy; GO:0060419 heart growth; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0016324 apical plasma membrane; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0030016 myofibril; GO:0005737 cytoplasm; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0030018 Z disc; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0031674 I band; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0005925 focal adhesion; GO:0098590 plasma membrane region; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0030027 lamellipodium; GO:0005912 adherens junction; GO:0043292 contractile fiber; GO:0048471 perinuclear region of cytoplasm; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0045177 apical part of cell; GO:0005924 cell-substrate adherens junction; GO:0031252 cell leading edge; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0070161 anchoring junction; GO:0015629 actin cytoskeleton; GO:0005886 plasma membrane; GO:0099081 supramolecular polymer; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0030017 sarcomere; GO:0044449 contractile fiber part; GO:0044444 cytoplasmic part; ","GO:0003723 RNA binding; GO:0030674 protein binding, bridging; GO:0043167 ion binding; GO:0005515 protein binding; GO:0008307 structural constituent of muscle; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0008092 cytoskeletal protein binding; GO:0005200 structural constituent of cytoskeleton; GO:0005488 binding; GO:0008093 cytoskeletal adaptor activity; GO:0003676 nucleic acid binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0060090 binding, bridging; GO:0005198 structural molecule activity; ",{"$nulls":3},"IPR001452; IPR003127; IPR007087; ","\"SH3 domain; SoHo domain; Zinc finger, C2H2; \"\r"]
["O94888","UBX domain-containing protein 7 OS=Homo sapiens OX=9606 GN=UBXN7","UBXN7",54.862,4.2881,2,1,1,1,0.916,0.947,0.927,1.09,1.05,1.07,1.151,0.000643,"nucleus\r",null,"GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0005789 endoplasmic reticulum membrane; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0044432 endoplasmic reticulum part; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0031625 ubiquitin protein ligase binding; GO:0005488 binding; GO:0043130 ubiquitin binding; GO:0005515 protein binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0008134 transcription factor binding; GO:0019899 enzyme binding; GO:0032182 ubiquitin-like protein binding; ",{"$nulls":3},"IPR006577; IPR001012; IPR029071; IPR012336; IPR009060; ","UAS; UBX domain; Ubiquitin-related domain; Thioredoxin-like fold; UBA-like; \r"]
["O94901","SUN domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SUN1","SUN1",90.063,45.625,8.7,6,7,6,1.033,1.152,1.115,0.939,0.92,0.919,0.842,6.62E-3,"cytoplasm\r","GO:0065008 regulation of biological quality; GO:0022414 reproductive process; GO:0007420 brain development; GO:0051647 nucleus localization; GO:0097240 chromosome attachment to the nuclear envelope; GO:0021987 cerebral cortex development; GO:0007097 nuclear migration; GO:0021537 telencephalon development; GO:0007129 synapsis; GO:0072595 maintenance of protein localization in organelle; GO:0009605 response to external stimulus; GO:0044702 single organism reproductive process; GO:0021885 forebrain cell migration; GO:0021815 modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration; GO:0033365 protein localization to organelle; GO:0051651 maintenance of location in cell; GO:0008104 protein localization; GO:0090292 nuclear matrix anchoring at nuclear membrane; GO:0044765 single-organism transport; GO:0007399 nervous system development; GO:0007059 chromosome segregation; GO:0032507 maintenance of protein location in cell; GO:0001503 ossification; GO:0061842 microtubule organizing center localization; GO:0045141 meiotic telomere clustering; GO:0019953 sexual reproduction; GO:0044763 single-organism cellular process; GO:0008347 glial cell migration; GO:0048870 cell motility; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0000226 microtubule cytoskeleton organization; GO:0022029 telencephalon cell migration; GO:0048513 animal organ development; GO:0042063 gliogenesis; GO:0007417 central nervous system development; GO:0070192 chromosome organization involved in meiotic cell cycle; GO:0048609 multicellular organismal reproductive process; GO:0000003 reproduction; GO:0051640 organelle localization; GO:0046907 intracellular transport; GO:0044707 single-multicellular organism process; GO:0009628 response to abiotic stimulus; GO:0043578 nuclear matrix organization; GO:0090220 chromosome localization to nuclear envelope involved in homologous chromosome segregation; GO:0030705 cytoskeleton-dependent intracellular transport; GO:0034398 telomere tethering at nuclear periphery; GO:0045143 homologous chromosome segregation; GO:1902578 single-organism localization; GO:0030900 forebrain development; GO:1902580 single-organism cellular localization; GO:0007275 multicellular organism development; GO:0034613 cellular protein localization; GO:0007010 cytoskeleton organization; GO:0021801 cerebral cortex radial glia guided migration; GO:0048731 system development; GO:0007283 spermatogenesis; GO:0051642 centrosome localization; GO:0070197 meiotic attachment of telomere to nuclear envelope; GO:0051656 establishment of organelle localization; GO:0007017 microtubule-based process; GO:0051276 chromosome organization; GO:0021817 nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration; GO:0098813 nuclear chromosome segregation; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0006928 movement of cell or subcellular component; GO:0000280 nuclear division; GO:0051179 localization; GO:0010256 endomembrane system organization; GO:0051674 localization of cell; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0040023 establishment of nucleus localization; GO:0051234 establishment of localization; GO:0051457 maintenance of protein location in nucleus; GO:0050000 chromosome localization; GO:0010970 transport along microtubule; GO:0051649 establishment of localization in cell; GO:0060322 head development; GO:0033036 macromolecule localization; GO:0045132 meiotic chromosome segregation; GO:0032502 developmental process; GO:0030473 nuclear migration along microtubule; GO:0051321 meiotic cell cycle; GO:1902582 single-organism intracellular transport; GO:1902589 single-organism organelle organization; GO:0040011 locomotion; GO:0048856 anatomical structure development; GO:0072384 organelle transport along microtubule; GO:0021543 pallium development; GO:0006997 nucleus organization; GO:0016043 cellular component organization; GO:0016477 cell migration; GO:0021799 cerebral cortex radially oriented cell migration; GO:1903046 meiotic cell cycle process; GO:0048285 organelle fission; GO:0021795 cerebral cortex cell migration; GO:0050896 response to stimulus; GO:0099111 microtubule-based transport; GO:0006998 nuclear envelope organization; GO:0009612 response to mechanical stimulus; GO:0007127 meiosis I; GO:0030154 cell differentiation; GO:0051235 maintenance of location; GO:0044821 meiotic telomere tethering at nuclear periphery; GO:0009987 cellular process; GO:0048232 male gamete generation; GO:0045185 maintenance of protein location; GO:0051303 establishment of chromosome localization; GO:0034397 telomere localization; GO:0044802 single-organism membrane organization; GO:0021814 cell motility involved in cerebral cortex radial glia guided migration; GO:0007276 gamete generation; GO:0051641 cellular localization; GO:0032504 multicellular organism reproduction; GO:0007018 microtubule-based movement; GO:0070727 cellular macromolecule localization; GO:0044767 single-organism developmental process; GO:0044703 multi-organism reproductive process; GO:0007126 meiotic nuclear division; GO:0022402 cell cycle process; GO:0090286 cytoskeletal anchoring at nuclear membrane; GO:0034504 protein localization to nucleus; GO:0022030 telencephalon glial cell migration; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0031224 intrinsic component of membrane; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031965 nuclear membrane; GO:0031229 intrinsic component of nuclear inner membrane; GO:0031301 integral component of organelle membrane; GO:0044425 membrane part; GO:0005622 intracellular; GO:0034992 microtubule organizing center attachment site; GO:0044464 cell part; GO:0005639 integral component of nuclear inner membrane; GO:0098805 whole membrane; GO:0099503 secretory vesicle; GO:0019866 organelle inner membrane; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0005637 nuclear inner membrane; GO:0043229 intracellular organelle; GO:0034993 LINC complex; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0005635 nuclear envelope; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0016021 integral component of membrane; GO:0002080 acrosomal membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0030667 secretory granule membrane; GO:0005634 nucleus; GO:0001669 acrosomal vesicle; GO:0031975 envelope; GO:0044453 nuclear membrane part; GO:0097223 sperm part; GO:0043234 protein complex; GO:0031300 intrinsic component of organelle membrane; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0005521 lamin binding; GO:0005488 binding; ","K19347",null,null,"IPR012919; IPR032680; ","\"SUN domain; SUN domain-containing protein 1, N-terminal; \"\r"]
["O94903","Pyridoxal phosphate homeostasis protein OS=Homo sapiens OX=9606 GN=PLPBP","PLPBP",30.344,36.587,25.1,6,7,6,0.995,1.161,1.134,0.882,0.918,0.93,0.83,0.0218,"cytoplasm\r",null,"GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0005488 binding; GO:0043167 ion binding; GO:0043168 anion binding; GO:0048037 cofactor binding; GO:0030170 pyridoxal phosphate binding; ","K06997",null,null,"IPR029066; IPR001608; ","\"PLP-binding barrel; Alanine racemase, N-terminal; \"\r"]
["O94905","Erlin-2 OS=Homo sapiens OX=9606 GN=ERLIN2","ERLIN2",37.839,46.005,25.4,7,10,4,0.98,1.103,1.16,0.866,0.957,0.948,0.854,0.0582,"extracellular\r","GO:0044700 single organism signaling; GO:0006066 alcohol metabolic process; GO:0009891 positive regulation of biosynthetic process; GO:0018212 peptidyl-tyrosine modification; GO:0036503 ERAD pathway; GO:0019216 regulation of lipid metabolic process; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:1902931 negative regulation of alcohol biosynthetic process; GO:0090181 regulation of cholesterol metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0008202 steroid metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0030163 protein catabolic process; GO:0044710 single-organism metabolic process; GO:0046890 regulation of lipid biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0042304 regulation of fatty acid biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0016310 phosphorylation; GO:0034976 response to endoplasmic reticulum stress; GO:1901615 organic hydroxy compound metabolic process; GO:0032933 SREBP signaling pathway; GO:0044267 cellular protein metabolic process; GO:0019218 regulation of steroid metabolic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:1902930 regulation of alcohol biosynthetic process; GO:0016125 sterol metabolic process; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0044248 cellular catabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0008203 cholesterol metabolic process; GO:0051254 positive regulation of RNA metabolic process; GO:0006950 response to stress; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0006984 ER-nucleus signaling pathway; GO:0009892 negative regulation of metabolic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0019217 regulation of fatty acid metabolic process; GO:0055085 transmembrane transport; GO:0009890 negative regulation of biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0045541 negative regulation of cholesterol biosynthetic process; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0045717 negative regulation of fatty acid biosynthetic process; GO:0051179 localization; GO:0043412 macromolecule modification; GO:0031328 positive regulation of cellular biosynthetic process; GO:0044699 single-organism process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0030433 ubiquitin-dependent ERAD pathway; GO:0090206 negative regulation of cholesterol metabolic process; GO:0009893 positive regulation of metabolic process; GO:0050810 regulation of steroid biosynthetic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0045922 negative regulation of fatty acid metabolic process; GO:0006629 lipid metabolic process; GO:0010468 regulation of gene expression; GO:0051055 negative regulation of lipid biosynthetic process; GO:0045833 negative regulation of lipid metabolic process; GO:0031326 regulation of cellular biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0023052 signaling; GO:0018108 peptidyl-tyrosine phosphorylation; GO:0010565 regulation of cellular ketone metabolic process; GO:0045939 negative regulation of steroid metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0019222 regulation of metabolic process; GO:0036211 protein modification process; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:1902652 secondary alcohol metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0010498 proteasomal protein catabolic process; GO:0071704 organic substance metabolic process; GO:0006468 protein phosphorylation; GO:0006508 proteolysis; GO:0009987 cellular process; GO:0043632 modification-dependent macromolecule catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0019941 modification-dependent protein catabolic process; GO:0044712 single-organism catabolic process; GO:0071501 cellular response to sterol depletion; GO:0045540 regulation of cholesterol biosynthetic process; GO:0006991 response to sterol depletion; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0018193 peptidyl-amino acid modification; GO:0010894 negative regulation of steroid biosynthetic process; GO:0009057 macromolecule catabolic process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0009056 catabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0098857 membrane microdomain; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0098589 membrane region; GO:1903561 extracellular vesicle; GO:0045121 membrane raft; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044432 endoplasmic reticulum part; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0015485 cholesterol binding; GO:0032934 sterol binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0031625 ubiquitin protein ligase binding; GO:0004713 protein tyrosine kinase activity; GO:0005515 protein binding; GO:0004672 protein kinase activity; GO:0005496 steroid binding; GO:0097159 organic cyclic compound binding; GO:0016301 kinase activity; GO:0003824 catalytic activity; GO:0043178 alcohol binding; GO:0005488 binding; GO:0008289 lipid binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0016740 transferase activity; GO:0019899 enzyme binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0036094 small molecule binding; ",{"$nulls":3},"IPR001107; ","Band 7 domain; \r"]
["O94906","Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6","PRPF6",106.92,16.682,6.4,6,6,6,0.952,0.912,0.982,1.174,0.932,1.053,1.11,0.225,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0022618 ribonucleoprotein complex assembly; GO:0009891 positive regulation of biosynthetic process; GO:0044237 cellular metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0071826 ribonucleoprotein complex subunit organization; GO:0009893 positive regulation of metabolic process; GO:0022607 cellular component assembly; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0065003 macromolecular complex assembly; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0043170 macromolecule metabolic process; GO:0033036 macromolecule localization; GO:0006396 RNA processing; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0016071 mRNA metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0009987 cellular process; GO:0008380 RNA splicing; GO:0034622 cellular macromolecular complex assembly; GO:0051254 positive regulation of RNA metabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0006403 RNA localization; GO:0006807 nitrogen compound metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0043933 macromolecular complex subunit organization; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0000244 spliceosomal tri-snRNP complex assembly; GO:0031325 positive regulation of cellular metabolic process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0010467 gene expression; GO:0031328 positive regulation of cellular biosynthetic process; GO:0051179 localization; GO:0000245 spliceosomal complex assembly; GO:0065007 biological regulation; GO:0000387 spliceosomal snRNP assembly; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044446 intracellular organelle part; GO:0046540 U4/U6 x U5 tri-snRNP complex; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005681 spliceosomal complex; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0097525 spliceosomal snRNP complex; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0097526 spliceosomal tri-snRNP complex; GO:0043226 organelle; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0044464 cell part; GO:0005622 intracellular; GO:0071013 catalytic step 2 spliceosome; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0030532 small nuclear ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0005682 U5 snRNP; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0003723 RNA binding; GO:0005102 receptor binding; GO:0044877 macromolecular complex binding; GO:0005515 protein binding; GO:0050681 androgen receptor binding; GO:0051427 hormone receptor binding; GO:0003712 transcription cofactor activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0035257 nuclear hormone receptor binding; GO:0035258 steroid hormone receptor binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0003713 transcription coactivator activity; GO:0000988 transcription factor activity, protein binding; GO:0043021 ribonucleoprotein complex binding; ","K12855","PRPF6; pre-mRNA-processing factor 6","hsa03040 Spliceosome - Homo sapiens (human); ","IPR010491; IPR011990; IPR013026; ","\"PRP1 splicing factor, N-terminal; Tetratricopeptide-like helical domain; Tetratricopeptide repeat-containing domain; \"\r"]
["O94911","ATP-binding cassette sub-family A member 8 OS=Homo sapiens OX=9606 GN=ABCA8","ABCA8",179.24,44.567,6.6,8,9,8,1.006,1.052,1.091,0.899,0.865,0.986,0.873,0.0397,"plasma membrane\r","GO:0006869 lipid transport; GO:0044699 single-organism process; GO:0071702 organic substance transport; GO:0010876 lipid localization; GO:0050896 response to stimulus; GO:0051234 establishment of localization; GO:0006810 transport; GO:0055085 transmembrane transport; GO:0042493 response to drug; GO:0042221 response to chemical; GO:1902578 single-organism localization; GO:0015893 drug transport; GO:0051179 localization; GO:0033036 macromolecule localization; GO:0042908 xenobiotic transport; GO:0006855 drug transmembrane transport; GO:0044765 single-organism transport; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044429 mitochondrial part; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005740 mitochondrial envelope; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0031975 envelope; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0015399 primary active transmembrane transporter activity; GO:0042910 xenobiotic transporter activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0016887 ATPase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0043492 ATPase activity, coupled to movement of substances; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0008559 xenobiotic-transporting ATPase activity; GO:0090484 drug transporter activity; GO:0005215 transporter activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0022804 active transmembrane transporter activity; GO:0005524 ATP binding; GO:0015238 drug transmembrane transporter activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity; GO:0042626 ATPase activity, coupled to transmembrane movement of substances; GO:0042623 ATPase activity, coupled; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0022857 transmembrane transporter activity; GO:0036094 small molecule binding; ","K05650","ABCA8; ATP-binding cassette, subfamily A (ABC1), member 8","hsa02010 ABC transporters - Homo sapiens (human); ","IPR003593; IPR003439; IPR027417; ","AAA+ ATPase domain; ABC transporter-like; P-loop containing nucleoside triphosphate hydrolase; \r"]
["O94919","Endonuclease domain-containing 1 protein OS=Homo sapiens OX=9606 GN=ENDOD1","ENDOD1",55.016,82.407,24,8,11,8,1.029,0.98,1.068,0.976,0.989,0.963,0.952,0.133,"plasma membrane\r","GO:0006725 cellular aromatic compound metabolic process; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0044699 single-organism process; GO:0002576 platelet degranulation; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0051234 establishment of localization; GO:0006810 transport; GO:0045055 regulated exocytosis; GO:0008152 metabolic process; GO:0090304 nucleic acid metabolic process; GO:0046483 heterocycle metabolic process; GO:1902578 single-organism localization; GO:0006139 nucleobase-containing compound metabolic process; GO:0032940 secretion by cell; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0090305 nucleic acid phosphodiester bond hydrolysis; GO:0051179 localization; GO:0009987 cellular process; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0006887 exocytosis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0003676 nucleic acid binding; GO:0004518 nuclease activity; GO:0016788 hydrolase activity, acting on ester bonds; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0016787 hydrolase activity; GO:0004519 endonuclease activity; ","K15049",null,null,"IPR020821; IPR001604; ","\"Extracellular Endonuclease, subunit A; DNA/RNA non-specific endonuclease; \"\r"]
["O94973","AP-2 complex subunit alpha-2 OS=Homo sapiens OX=9606 GN=AP2A2","AP2A2",103.96,165.81,27.3,23,30,15,1.029,1.025,1.018,0.962,0.938,0.966,0.933,0.00202,"cytoplasm\r","GO:0044700 single organism signaling; GO:0045321 leukocyte activation; GO:0007166 cell surface receptor signaling pathway; GO:0044699 single-organism process; GO:0031347 regulation of defense response; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0035567 non-canonical Wnt signaling pathway; GO:1905330 regulation of morphogenesis of an epithelium; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0050690 regulation of defense response to virus by virus; GO:0016055 Wnt signaling pathway; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0002697 regulation of immune effector process; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0048002 antigen processing and presentation of peptide antigen; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0023052 signaling; GO:0002495 antigen processing and presentation of peptide antigen via MHC class II; GO:0002444 myeloid leukocyte mediated immunity; GO:0198738 cell-cell signaling by wnt; GO:0006810 transport; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0050789 regulation of biological process; GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0007267 cell-cell signaling; GO:0032940 secretion by cell; GO:0048583 regulation of response to stimulus; GO:0060071 Wnt signaling pathway, planar cell polarity pathway; GO:0002682 regulation of immune system process; GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II; GO:0043299 leukocyte degranulation; GO:2000026 regulation of multicellular organismal development; GO:0050794 regulation of cellular process; GO:0090175 regulation of establishment of planar polarity; GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0002283 neutrophil activation involved in immune response; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0002831 regulation of response to biotic stimulus; GO:0002252 immune effector process; GO:0080134 regulation of response to stress; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:0050688 regulation of defense response to virus; GO:0072583 clathrin-dependent endocytosis; GO:2000027 regulation of organ morphogenesis; GO:0048013 ephrin receptor signaling pathway; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0006886 intracellular protein transport; GO:0006898 receptor-mediated endocytosis; GO:0036230 granulocyte activation; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0043900 regulation of multi-organism process; GO:0016192 vesicle-mediated transport; GO:0050792 regulation of viral process; GO:0032101 regulation of response to external stimulus; GO:0071702 organic substance transport; GO:0002376 immune system process; GO:0006897 endocytosis; GO:0043312 neutrophil degranulation; GO:0007017 microtubule-based process; GO:0002263 cell activation involved in immune response; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0002366 leukocyte activation involved in immune response; GO:0019882 antigen processing and presentation; GO:0007018 microtubule-based movement; GO:0045055 regulated exocytosis; GO:0070727 cellular macromolecule localization; GO:0042119 neutrophil activation; GO:0022603 regulation of anatomical structure morphogenesis; GO:0061024 membrane organization; GO:0006928 movement of cell or subcellular component; GO:0001775 cell activation; GO:0006955 immune response; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0071840 cellular component organization or biogenesis; GO:0006887 exocytosis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0030119 AP-type membrane coat adaptor complex; GO:0031090 organelle membrane; GO:0045334 clathrin-coated endocytic vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0036019 endolysosome; GO:0005623 cell; GO:0044422 organelle part; GO:0005765 lysosomal membrane; GO:0030136 clathrin-coated vesicle; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:0098589 membrane region; GO:0043227 membrane-bounded organelle; GO:0000323 lytic vacuole; GO:0010008 endosome membrane; GO:0030666 endocytic vesicle membrane; GO:0048475 coated membrane; GO:0036020 endolysosome membrane; GO:0098797 plasma membrane protein complex; GO:0044440 endosomal part; GO:0012506 vesicle membrane; GO:0030135 coated vesicle; GO:0005886 plasma membrane; GO:0030125 clathrin vesicle coat; GO:0043231 intracellular membrane-bounded organelle; GO:0030667 secretory granule membrane; GO:0101003 ficolin-1-rich granule membrane; GO:0030122 AP-2 adaptor complex; GO:0030131 clathrin adaptor complex; GO:0044437 vacuolar part; GO:0030118 clathrin coat; GO:0005773 vacuole; GO:0030117 membrane coat; GO:0043234 protein complex; GO:0005905 clathrin-coated pit; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0030669 clathrin-coated endocytic vesicle membrane; GO:0044424 intracellular part; GO:0030120 vesicle coat; GO:0030662 coated vesicle membrane; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0005768 endosome; GO:0030141 secretory granule; GO:0030132 clathrin coat of coated pit; GO:0030139 endocytic vesicle; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0070820 tertiary granule; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0030665 clathrin-coated vesicle membrane; GO:0030128 clathrin coat of endocytic vesicle; GO:0030659 cytoplasmic vesicle membrane; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0005774 vacuolar membrane; GO:0044444 cytoplasmic part; ","GO:0008565 protein transporter activity; GO:0005488 binding; GO:0019901 protein kinase binding; GO:0008289 lipid binding; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0019900 kinase binding; GO:0019899 enzyme binding; GO:0005215 transporter activity; ","K11824","AP2A; AP-2 complex subunit alpha","hsa05016 Huntington's disease - Homo sapiens (human); hsa04144 Endocytosis - Homo sapiens (human); hsa04961 Endocrine and other factor-regulated calcium reabsorption - Homo sapiens (human); hsa04721 Synaptic vesicle cycle - Homo sapiens (human); ","IPR008152; IPR011989; IPR013038; IPR002553; IPR003164; IPR016024; IPR009028; IPR015873; IPR013041; ","\"Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain; Armadillo-like helical; Clathrin adaptor, alpha-adaptin, appendage, Ig-like subdomain; Clathrin/coatomer adaptor, adaptin-like, N-terminal; Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain; Armadillo-type fold; Coatomer/calthrin adaptor appendage, C-terminal subdomain; Clathrin alpha-adaptin/coatomer adaptor, appendage, C-terminal subdomain; Coatomer/clathrin adaptor appendage, Ig-like subdomain; \"\r"]
["O94979","Protein transport protein Sec31A OS=Homo sapiens OX=9606 GN=SEC31A","SEC31A",133.01,81.352,12.5,15,21,15,1.086,1.037,1.042,0.982,0.969,0.955,0.918,0.007,"nucleus\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0006901 vesicle coating; GO:0048207 vesicle targeting, rough ER to cis-Golgi; GO:0048208 COPII vesicle coating; GO:0044699 single-organism process; GO:0015031 protein transport; GO:0030968 endoplasmic reticulum unfolded protein response; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:0035966 response to topologically incorrect protein; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0048199 vesicle targeting, to, from or within Golgi; GO:0010035 response to inorganic substance; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0070887 cellular response to chemical stimulus; GO:0051716 cellular response to stimulus; GO:0051650 establishment of vesicle localization; GO:0071822 protein complex subunit organization; GO:0048002 antigen processing and presentation of peptide antigen; GO:0044763 single-organism cellular process; GO:0023052 signaling; GO:0002495 antigen processing and presentation of peptide antigen via MHC class II; GO:0010038 response to metal ion; GO:0006810 transport; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II; GO:0070271 protein complex biogenesis; GO:0051640 organelle localization; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0033554 cellular response to stress; GO:0035967 cellular response to topologically incorrect protein; GO:0034976 response to endoplasmic reticulum stress; GO:0071310 cellular response to organic substance; GO:0048193 Golgi vesicle transport; GO:0036498 IRE1-mediated unfolded protein response; GO:0006903 vesicle targeting; GO:0050896 response to stimulus; GO:0051648 vesicle localization; GO:0051592 response to calcium ion; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0006986 response to unfolded protein; GO:0034620 cellular response to unfolded protein; GO:0006950 response to stress; GO:0090114 COPII-coated vesicle budding; GO:0016192 vesicle-mediated transport; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:0016050 vesicle organization; GO:0002376 immune system process; GO:0071702 organic substance transport; GO:0010033 response to organic substance; GO:0051656 establishment of organelle localization; GO:0051641 cellular localization; GO:0043933 macromolecular complex subunit organization; GO:0045184 establishment of protein localization; GO:0019882 antigen processing and presentation; GO:0006996 organelle organization; GO:0006900 membrane budding; GO:0061024 membrane organization; GO:0051179 localization; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0030658 transport vesicle membrane; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0030120 vesicle coat; GO:0005623 cell; GO:0030662 coated vesicle membrane; GO:0044422 organelle part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0048471 perinuclear region of cytoplasm; GO:0044431 Golgi apparatus part; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0012507 ER to Golgi transport vesicle membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0048475 coated membrane; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0030134 ER to Golgi transport vesicle; GO:0012506 vesicle membrane; GO:0005829 cytosol; GO:0030135 coated vesicle; GO:0030659 cytoplasmic vesicle membrane; GO:0070971 endoplasmic reticulum exit site; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044432 endoplasmic reticulum part; GO:0030117 membrane coat; GO:0030127 COPII vesicle coat; GO:0043234 protein complex; GO:0005794 Golgi apparatus; GO:0030133 transport vesicle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0048306 calcium-dependent protein binding; GO:0005488 binding; ","K14005","SEC31; protein transport protein SEC31","hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); ","IPR017986; IPR015943; IPR024298; ","\"WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain; Ancestral coatomer element 1, Sec16/Sec31; \"\r"]
["O94992","Protein HEXIM1 OS=Homo sapiens OX=9606 GN=HEXIM1","HEXIM1",40.623,2.7363,3.9,2,2,2,0.836,0.803,0.927,1.232,1.072,1.12,1.334,0.00824,"nucleus\r","GO:0097659 nucleic acid-templated transcription; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0051253 negative regulation of RNA metabolic process; GO:0031400 negative regulation of protein modification process; GO:0071900 regulation of protein serine/threonine kinase activity; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0010646 regulation of cell communication; GO:0007507 heart development; GO:0071901 negative regulation of protein serine/threonine kinase activity; GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity; GO:0033673 negative regulation of kinase activity; GO:0043170 macromolecule metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0051726 regulation of cell cycle; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0032502 developmental process; GO:0042325 regulation of phosphorylation; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0051174 regulation of phosphorus metabolic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0000122 negative regulation of transcription from RNA polymerase II promoter; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0032774 RNA biosynthetic process; GO:0051348 negative regulation of transferase activity; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0032268 regulation of cellular protein metabolic process; GO:1904030 negative regulation of cyclin-dependent protein kinase activity; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:1901798 positive regulation of signal transduction by p53 class mediator; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0048583 regulation of response to stimulus; GO:1902679 negative regulation of RNA biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0006469 negative regulation of protein kinase activity; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0048856 anatomical structure development; GO:1901362 organic cyclic compound biosynthetic process; GO:0043549 regulation of kinase activity; GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0072359 circulatory system development; GO:0045859 regulation of protein kinase activity; GO:0044707 single-multicellular organism process; GO:0045786 negative regulation of cell cycle; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031399 regulation of protein modification process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0048523 negative regulation of cellular process; GO:1904029 regulation of cyclin-dependent protein kinase activity; GO:0071704 organic substance metabolic process; GO:0045892 negative regulation of transcription, DNA-templated; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0042326 negative regulation of phosphorylation; GO:0009889 regulation of biosynthetic process; GO:0023056 positive regulation of signaling; GO:0051338 regulation of transferase activity; GO:1901796 regulation of signal transduction by p53 class mediator; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0001933 negative regulation of protein phosphorylation; GO:0007275 multicellular organism development; GO:0010647 positive regulation of cell communication; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0009966 regulation of signal transduction; GO:0006355 regulation of transcription, DNA-templated; GO:1902531 regulation of intracellular signal transduction; GO:0010629 negative regulation of gene expression; GO:0048731 system development; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0001932 regulation of protein phosphorylation; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0009890 negative regulation of biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0010563 negative regulation of phosphorus metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0010467 gene expression; GO:0031327 negative regulation of cellular biosynthetic process; GO:0009967 positive regulation of signal transduction; GO:0048584 positive regulation of response to stimulus; GO:0045936 negative regulation of phosphate metabolic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0030291 protein serine/threonine kinase inhibitor activity; GO:0003723 RNA binding; GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity; GO:0005515 protein binding; GO:0004860 protein kinase inhibitor activity; GO:0019887 protein kinase regulator activity; GO:0019207 kinase regulator activity; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0097322 7SK snRNA binding; GO:0030234 enzyme regulator activity; GO:0019210 kinase inhibitor activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity; GO:0017069 snRNA binding; ","K15189"]
["O95081","Arf-GAP domain and FG repeat-containing protein 2 OS=Homo sapiens OX=9606 GN=AGFG2","AGFG2",48.962,6.0772,5.4,2,2,2,1.05,0.959,1.286,0.832,1.066,0.817,0.824,0.188,"nucleus\r","GO:0051336 regulation of hydrolase activity; GO:0043547 positive regulation of GTPase activity; GO:0051345 positive regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0044093 positive regulation of molecular function; GO:0065009 regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0065007 biological regulation; GO:0043085 positive regulation of catalytic activity; ","GO:0016020 membrane; ","GO:0030234 enzyme regulator activity; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0005488 binding; GO:0030695 GTPase regulator activity; GO:0043167 ion binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0098772 molecular function regulator; GO:0008047 enzyme activator activity; GO:0005096 GTPase activator activity; "]
["O95136","Sphingosine 1-phosphate receptor 2 OS=Homo sapiens OX=9606 GN=S1PR2","S1PR2",38.867,1.7467,3.1,1,1,1,1.12,1.164,1.11,0.904,0.864,0.866,0.776,0.000258,"plasma membrane\r","GO:0044700 single organism signaling; GO:0090520 sphingolipid mediated signaling pathway; GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0046847 filopodium assembly; GO:0032270 positive regulation of cellular protein metabolic process; GO:0009968 negative regulation of signal transduction; GO:0098815 modulation of excitatory postsynaptic potential; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0030858 positive regulation of epithelial cell differentiation; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0030036 actin cytoskeleton organization; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0022607 cellular component assembly; GO:0044093 positive regulation of molecular function; GO:0010800 positive regulation of peptidyl-threonine phosphorylation; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0051347 positive regulation of transferase activity; GO:0033674 positive regulation of kinase activity; GO:0010720 positive regulation of cell development; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0051174 regulation of phosphorus metabolic process; GO:0050805 negative regulation of synaptic transmission; GO:0045937 positive regulation of phosphate metabolic process; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0031323 regulation of cellular metabolic process; GO:0023052 signaling; GO:0042391 regulation of membrane potential; GO:0031532 actin cytoskeleton reorganization; GO:1902589 single-organism organelle organization; GO:0030856 regulation of epithelial cell differentiation; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0030030 cell projection organization; GO:0050790 regulation of catalytic activity; GO:0045603 positive regulation of endothelial cell differentiation; GO:0048583 regulation of response to stimulus; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0051094 positive regulation of developmental process; GO:0043549 regulation of kinase activity; GO:2000026 regulation of multicellular organismal development; GO:0050794 regulation of cellular process; GO:0045859 regulation of protein kinase activity; GO:0016043 cellular component organization; GO:0042127 regulation of cell proliferation; GO:0010799 regulation of peptidyl-threonine phosphorylation; GO:0043405 regulation of MAP kinase activity; GO:0060255 regulation of macromolecule metabolic process; GO:0031399 regulation of protein modification process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0071902 positive regulation of protein serine/threonine kinase activity; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:0045597 positive regulation of cell differentiation; GO:0003376 sphingosine-1-phosphate signaling pathway; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0032147 activation of protein kinase activity; GO:0043408 regulation of MAPK cascade; GO:0023056 positive regulation of signaling; GO:0051338 regulation of transferase activity; GO:0090394 negative regulation of excitatory postsynaptic potential; GO:0010647 positive regulation of cell communication; GO:0007010 cytoskeleton organization; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:1901550 regulation of endothelial cell development; GO:0045595 regulation of cell differentiation; GO:1902531 regulation of intracellular signal transduction; GO:0050804 modulation of synaptic transmission; GO:0060284 regulation of cell development; GO:0001932 regulation of protein phosphorylation; GO:0031401 positive regulation of protein modification process; GO:0048585 negative regulation of response to stimulus; GO:0045860 positive regulation of protein kinase activity; GO:0001934 positive regulation of protein phosphorylation; GO:0048518 positive regulation of biological process; GO:0045601 regulation of endothelial cell differentiation; GO:1903142 positive regulation of establishment of endothelial barrier; GO:0030031 cell projection assembly; GO:0043085 positive regulation of catalytic activity; GO:0007186 G-protein coupled receptor signaling pathway; GO:0000187 activation of MAPK activity; GO:0051247 positive regulation of protein metabolic process; GO:0043406 positive regulation of MAP kinase activity; GO:1901552 positive regulation of endothelial cell development; GO:0051246 regulation of protein metabolic process; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0030029 actin filament-based process; GO:0009967 positive regulation of signal transduction; GO:0043410 positive regulation of MAPK cascade; GO:0048584 positive regulation of response to stimulus; GO:0050793 regulation of developmental process; GO:1903140 regulation of establishment of endothelial barrier; GO:0008284 positive regulation of cell proliferation; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044464 cell part; GO:0071944 cell periphery; GO:0044425 membrane part; GO:0031224 intrinsic component of membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; ","GO:0038023 signaling receptor activity; GO:0005102 receptor binding; GO:0038036 sphingosine-1-phosphate receptor activity; GO:0044877 macromolecular complex binding; GO:0004930 G-protein coupled receptor activity; GO:0005178 integrin binding; GO:0005515 protein binding; GO:0004888 transmembrane signaling receptor activity; GO:0004871 signal transducer activity; GO:0045125 bioactive lipid receptor activity; GO:0050839 cell adhesion molecule binding; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0005488 binding; GO:0008289 lipid binding; GO:0001664 G-protein coupled receptor binding; GO:0032403 protein complex binding; GO:0099600 transmembrane receptor activity; ","K04292","S1PR2; sphingosine 1-phosphate receptor 2","hsa04071 Sphingolipid signaling pathway - Homo sapiens (human); hsa04080 Neuroactive ligand-receptor interaction - Homo sapiens (human); ","IPR017452; ","\"GPCR, rhodopsin-like, 7TM; \"\r"]
["O95139","NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 OS=Homo sapiens OX=9606 GN=NDUFB6","NDUFB6",15.489,17.726,26.6,3,5,3,1.012,1.047,1.029,0.984,0.936,1.016,0.951,0.12,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0022607 cellular component assembly; GO:0006753 nucleoside phosphate metabolic process; GO:0065003 macromolecular complex assembly; GO:0007005 mitochondrion organization; GO:0019693 ribose phosphate metabolic process; GO:0071822 protein complex subunit organization; GO:0010257 NADH dehydrogenase complex assembly; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0006119 oxidative phosphorylation; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0006120 mitochondrial electron transport, NADH to ubiquinone; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0097031 mitochondrial respiratory chain complex I biogenesis; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0022900 electron transport chain; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0070271 protein complex biogenesis; GO:0033108 mitochondrial respiratory chain complex assembly; GO:0016043 cellular component organization; GO:0016310 phosphorylation; GO:0006725 cellular aromatic compound metabolic process; GO:0042773 ATP synthesis coupled electron transport; GO:0009259 ribonucleotide metabolic process; GO:0022904 respiratory electron transport chain; GO:0071704 organic substance metabolic process; GO:0032981 mitochondrial respiratory chain complex I assembly; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0009119 ribonucleoside metabolic process; GO:0006461 protein complex assembly; GO:0043623 cellular protein complex assembly; GO:0046034 ATP metabolic process; GO:0034622 cellular macromolecular complex assembly; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0045333 cellular respiration; GO:0006163 purine nucleotide metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0046128 purine ribonucleoside metabolic process; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:1901564 organonitrogen compound metabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0045271 respiratory chain complex I; GO:0032991 macromolecular complex; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0005747 mitochondrial respiratory chain complex I; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0098803 respiratory chain complex; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0031981 nuclear lumen; GO:0016021 integral component of membrane; GO:0005739 mitochondrion; GO:0005746 mitochondrial respiratory chain; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0030964 NADH dehydrogenase complex; GO:0031975 envelope; GO:1990204 oxidoreductase complex; GO:0043234 protein complex; GO:0031966 mitochondrial membrane; GO:0070469 respiratory chain; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0050136 NADH dehydrogenase (quinone) activity; GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:0003954 NADH dehydrogenase activity; GO:0003824 catalytic activity; GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; GO:0008137 NADH dehydrogenase (ubiquinone) activity; GO:0016491 oxidoreductase activity; ","K03962","NDUFB6; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6","hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); "]
["O95155","Ubiquitin conjugation factor E4 B OS=Homo sapiens OX=9606 GN=UBE4B","UBE4B",146.18,6.3056,3.2,4,4,4,0.974,1.015,0.902,1.067,1.034,1.016,1.078,0.111,"cyto_nucl\r","GO:0044700 single organism signaling; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0060415 muscle tissue morphogenesis; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0036503 ERAD pathway; GO:0051865 protein autoubiquitination; GO:0044237 cellular metabolic process; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0048729 tissue morphogenesis; GO:0007507 heart development; GO:0030433 ubiquitin-dependent ERAD pathway; GO:0007154 cell communication; GO:0006915 apoptotic process; GO:0003208 cardiac ventricle morphogenesis; GO:0009314 response to radiation; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0009888 tissue development; GO:0048699 generation of neurons; GO:0060537 muscle tissue development; GO:0055008 cardiac muscle tissue morphogenesis; GO:0003007 heart morphogenesis; GO:0044763 single-organism cellular process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0023052 signaling; GO:0061383 trabecula morphogenesis; GO:0032501 multicellular organismal process; GO:1901575 organic substance catabolic process; GO:0048513 animal organ development; GO:0042221 response to chemical; GO:0006513 protein monoubiquitination; GO:0050789 regulation of biological process; GO:0003229 ventricular cardiac muscle tissue development; GO:0030030 cell projection organization; GO:0007517 muscle organ development; GO:0044710 single-organism metabolic process; GO:0030163 protein catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0048644 muscle organ morphogenesis; GO:0009887 animal organ morphogenesis; GO:0006464 cellular protein modification process; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0050794 regulation of cellular process; GO:0014706 striated muscle tissue development; GO:0072359 circulatory system development; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0033554 cellular response to stress; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0097190 apoptotic signaling pathway; GO:0044257 cellular protein catabolic process; GO:0048738 cardiac muscle tissue development; GO:0034976 response to endoplasmic reticulum stress; GO:0009628 response to abiotic stimulus; GO:0008626 granzyme-mediated apoptotic signaling pathway; GO:0044267 cellular protein metabolic process; GO:0050896 response to stimulus; GO:0010498 proteasomal protein catabolic process; GO:0048468 cell development; GO:0000209 protein polyubiquitination; GO:0071704 organic substance metabolic process; GO:0061384 heart trabecula morphogenesis; GO:0009653 anatomical structure morphogenesis; GO:0030154 cell differentiation; GO:0055010 ventricular cardiac muscle tissue morphogenesis; GO:0061061 muscle structure development; GO:0044248 cellular catabolic process; GO:0006508 proteolysis; GO:0007275 multicellular organism development; GO:0003231 cardiac ventricle development; GO:0009987 cellular process; GO:0003222 ventricular trabecula myocardium morphogenesis; GO:0043632 modification-dependent macromolecule catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0009416 response to light stimulus; GO:0006950 response to stress; GO:0016567 protein ubiquitination; GO:0019941 modification-dependent protein catabolic process; GO:0044712 single-organism catabolic process; GO:0048731 system development; GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0010033 response to organic substance; GO:0031175 neuron projection development; GO:0003206 cardiac chamber morphogenesis; GO:0044238 primary metabolic process; GO:0003205 cardiac chamber development; GO:0030182 neuron differentiation; GO:0009411 response to UV; GO:0032446 protein modification by small protein conjugation; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0009057 macromolecule catabolic process; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0012501 programmed cell death; GO:0043412 macromolecule modification; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:1902494 catalytic complex; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:1990234 transferase complex; GO:0000151 ubiquitin ligase complex; GO:0043227 membrane-bounded organelle; GO:0005623 cell; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0019787 ubiquitin-like protein transferase activity; GO:0051117 ATPase binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0034450 ubiquitin-ubiquitin ligase activity; GO:0005515 protein binding; GO:0061659 ubiquitin-like protein ligase activity; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0061630 ubiquitin protein ligase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0004842 ubiquitin-protein transferase activity; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0016740 transferase activity; GO:0019899 enzyme binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K10597","UBE4B; ubiquitin conjugation factor E4 B [EC:2.3.2.27]","hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human); hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); ","IPR019474; IPR003613; IPR013083; ","\"Ubiquitin conjugation factor E4, core; U box domain; Zinc finger, RING/FYVE/PHD-type; \"\r"]
["O95159","Zinc finger protein-like 1 OS=Homo sapiens OX=9606 GN=ZFPL1","ZFPL1",34.114,10.548,7.7,2,2,2,0.979,1.067,0.952,0.919,1.013,1.076,1.003,0.968,"nucleus\r","GO:0050794 regulation of cellular process; GO:0010468 regulation of gene expression; GO:0006355 regulation of transcription, DNA-templated; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0016192 vesicle-mediated transport; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0051234 establishment of localization; GO:0006810 transport; GO:2001141 regulation of RNA biosynthetic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0019222 regulation of metabolic process; GO:0051179 localization; GO:0065007 biological regulation; GO:2000112 regulation of cellular macromolecule biosynthetic process; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003677 DNA binding; GO:0046914 transition metal ion binding; GO:0005488 binding; GO:0043167 ion binding; GO:0003676 nucleic acid binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0008270 zinc ion binding; ",{"$nulls":3},"IPR013083; ","\"Zinc finger, RING/FYVE/PHD-type; \"\r"]
["O95163","Elongator complex protein 1 OS=Homo sapiens OX=9606 GN=ELP1","ELP1",150.25,10.534,2.6,2,2,2,0.907,1.107,1.145,1.004,0.951,0.901,0.904,0.289,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0030335 positive regulation of cell migration; GO:0097659 nucleic acid-templated transcription; GO:0040017 positive regulation of locomotion; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0006354 DNA-templated transcription, elongation; GO:0009451 RNA modification; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0032879 regulation of localization; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0051174 regulation of phosphorus metabolic process; GO:0071822 protein complex subunit organization; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0032774 RNA biosynthetic process; GO:0051272 positive regulation of cellular component movement; GO:0023052 signaling; GO:0031323 regulation of cellular metabolic process; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0050790 regulation of catalytic activity; GO:0008033 tRNA processing; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0006464 cellular protein modification process; GO:0019220 regulation of phosphate metabolic process; GO:0070271 protein complex biogenesis; GO:0036211 protein modification process; GO:1901362 organic cyclic compound biosynthetic process; GO:0043549 regulation of kinase activity; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0045859 regulation of protein kinase activity; GO:0016043 cellular component organization; GO:0016310 phosphorylation; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0031399 regulation of protein modification process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044267 cellular protein metabolic process; GO:2000147 positive regulation of cell motility; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0002098 tRNA wobble uridine modification; GO:0006468 protein phosphorylation; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:2000145 regulation of cell motility; GO:0009889 regulation of biosynthetic process; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0006400 tRNA modification; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0006355 regulation of transcription, DNA-templated; GO:0051270 regulation of cellular component movement; GO:0001932 regulation of protein phosphorylation; GO:0006368 transcription elongation from RNA polymerase II promoter; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0006807 nitrogen compound metabolic process; GO:0002376 immune system process; GO:0030334 regulation of cell migration; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0006399 tRNA metabolic process; GO:0002097 tRNA wobble base modification; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0051246 regulation of protein metabolic process; GO:0006366 transcription from RNA polymerase II promoter; GO:0010467 gene expression; GO:0006955 immune response; GO:0043412 macromolecule modification; GO:0040012 regulation of locomotion; GO:0034660 ncRNA metabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0000123 histone acetyltransferase complex; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0031248 protein acetyltransferase complex; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:1902493 acetyltransferase complex; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:1990234 transferase complex; GO:0005829 cytosol; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0008023 transcription elongation factor complex; GO:0043234 protein complex; GO:0033588 Elongator holoenzyme complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0005515 protein binding; GO:0019887 protein kinase regulator activity; GO:0019207 kinase regulator activity; GO:0098772 molecular function regulator; GO:0008607 phosphorylase kinase regulator activity; GO:0004871 signal transducer activity; ","K11373",null,null,"IPR011042; ","\"Six-bladed beta-propeller, TolB-like; \"\r"]
["O95168","NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 OS=Homo sapiens OX=9606 GN=NDUFB4","NDUFB4",15.208,26.566,14,1,1,1,1.037,0.959,1.046,0.976,1.031,0.959,0.975,0.516,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0022607 cellular component assembly; GO:0006753 nucleoside phosphate metabolic process; GO:0065003 macromolecular complex assembly; GO:0007005 mitochondrion organization; GO:0006979 response to oxidative stress; GO:0019693 ribose phosphate metabolic process; GO:0071822 protein complex subunit organization; GO:0010257 NADH dehydrogenase complex assembly; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0006119 oxidative phosphorylation; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0006120 mitochondrial electron transport, NADH to ubiquinone; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0097031 mitochondrial respiratory chain complex I biogenesis; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0022900 electron transport chain; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0070271 protein complex biogenesis; GO:0033108 mitochondrial respiratory chain complex assembly; GO:0016043 cellular component organization; GO:0016310 phosphorylation; GO:0006725 cellular aromatic compound metabolic process; GO:0042773 ATP synthesis coupled electron transport; GO:0009259 ribonucleotide metabolic process; GO:0022904 respiratory electron transport chain; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0032981 mitochondrial respiratory chain complex I assembly; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0009119 ribonucleoside metabolic process; GO:0006461 protein complex assembly; GO:0043623 cellular protein complex assembly; GO:0046034 ATP metabolic process; GO:0034622 cellular macromolecular complex assembly; GO:0006950 response to stress; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0045333 cellular respiration; GO:0006163 purine nucleotide metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0046128 purine ribonucleoside metabolic process; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:1901564 organonitrogen compound metabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0045271 respiratory chain complex I; GO:0032991 macromolecular complex; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0005747 mitochondrial respiratory chain complex I; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0070062 extracellular exosome; GO:1902494 catalytic complex; GO:0031965 nuclear membrane; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0019866 organelle inner membrane; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0098803 respiratory chain complex; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0005635 nuclear envelope; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005746 mitochondrial respiratory chain; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0030964 NADH dehydrogenase complex; GO:1990204 oxidoreductase complex; GO:0031975 envelope; GO:0043234 protein complex; GO:0031966 mitochondrial membrane; GO:0070469 respiratory chain; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0050136 NADH dehydrogenase (quinone) activity; GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:0003954 NADH dehydrogenase activity; GO:0003824 catalytic activity; GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; GO:0008137 NADH dehydrogenase (ubiquinone) activity; GO:0016491 oxidoreductase activity; ","K03960","NDUFB4; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4","hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); "]
["O95169","NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFB8","NDUFB8",21.766,2.4121,11.8,2,2,2,1.01,0.97,1.027,1.007,0.984,1.011,0.998,0.943,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0022607 cellular component assembly; GO:0006753 nucleoside phosphate metabolic process; GO:0065003 macromolecular complex assembly; GO:0007005 mitochondrion organization; GO:0019693 ribose phosphate metabolic process; GO:0071822 protein complex subunit organization; GO:0010257 NADH dehydrogenase complex assembly; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0006119 oxidative phosphorylation; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0006120 mitochondrial electron transport, NADH to ubiquinone; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0097031 mitochondrial respiratory chain complex I biogenesis; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0022900 electron transport chain; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0070271 protein complex biogenesis; GO:0033108 mitochondrial respiratory chain complex assembly; GO:0016043 cellular component organization; GO:0016310 phosphorylation; GO:0006725 cellular aromatic compound metabolic process; GO:0042773 ATP synthesis coupled electron transport; GO:0009259 ribonucleotide metabolic process; GO:0022904 respiratory electron transport chain; GO:0071704 organic substance metabolic process; GO:0032981 mitochondrial respiratory chain complex I assembly; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0009119 ribonucleoside metabolic process; GO:0006461 protein complex assembly; GO:0043623 cellular protein complex assembly; GO:0046034 ATP metabolic process; GO:0034622 cellular macromolecular complex assembly; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0045333 cellular respiration; GO:0006163 purine nucleotide metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0046128 purine ribonucleoside metabolic process; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:1901564 organonitrogen compound metabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0045271 respiratory chain complex I; GO:0032991 macromolecular complex; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0005747 mitochondrial respiratory chain complex I; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:1902494 catalytic complex; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0098803 respiratory chain complex; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0016021 integral component of membrane; GO:0005739 mitochondrion; GO:0005746 mitochondrial respiratory chain; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0030964 NADH dehydrogenase complex; GO:0031975 envelope; GO:1990204 oxidoreductase complex; GO:0043234 protein complex; GO:0031966 mitochondrial membrane; GO:0070469 respiratory chain; GO:0044444 cytoplasmic part; ","GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:0003954 NADH dehydrogenase activity; GO:0003824 catalytic activity; GO:0050136 NADH dehydrogenase (quinone) activity; GO:0008137 NADH dehydrogenase (ubiquinone) activity; GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; GO:0016491 oxidoreductase activity; ","K03964","NDUFB8; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8","hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); "]
["O95171","Sciellin OS=Homo sapiens OX=9606 GN=SCEL","SCEL",77.551,29.541,17.3,12,14,12,1.036,1.008,1.018,0.973,0.967,1.008,0.963,0.0667,"nucleus\r","GO:0032502 developmental process; GO:0060429 epithelium development; GO:0044707 single-multicellular organism process; GO:0043588 skin development; GO:0030216 keratinocyte differentiation; GO:0009888 tissue development; GO:0048731 system development; GO:0048869 cellular developmental process; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0032501 multicellular organismal process; GO:0009913 epidermal cell differentiation; GO:0030154 cell differentiation; GO:0048513 animal organ development; GO:0044767 single-organism developmental process; GO:0008544 epidermis development; GO:0007275 multicellular organism development; GO:0009790 embryo development; GO:0048856 anatomical structure development; GO:0009987 cellular process; GO:0030855 epithelial cell differentiation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0001533 cornified envelope; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0046914 transition metal ion binding; GO:0005488 binding; GO:0043167 ion binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0008270 zinc ion binding; ",{"$nulls":3},"IPR001781; ","\"Zinc finger, LIM-type; \"\r"]
["O95197","Reticulon-3 OS=Homo sapiens OX=9606 GN=RTN3","RTN3",112.61,2.7659,1.1,1,2,1,1.016,1.04,1.041,0.832,1.016,1.061,0.939,0.462,"plasma membrane\r","GO:0044085 cellular component biogenesis; GO:0016043 cellular component organization; GO:0010256 endomembrane system organization; GO:0071787 endoplasmic reticulum tubular network formation; GO:0016192 vesicle-mediated transport; GO:0071786 endoplasmic reticulum tubular network organization; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0044764 multi-organism cellular process; GO:0051704 multi-organism process; GO:0051234 establishment of localization; GO:0006810 transport; GO:0008219 cell death; GO:0022607 cellular component assembly; GO:0016032 viral process; GO:0006996 organelle organization; GO:0006915 apoptotic process; GO:0012501 programmed cell death; GO:0051179 localization; GO:0044419 interspecies interaction between organisms; GO:0009987 cellular process; GO:0007029 endoplasmic reticulum organization; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005615 extracellular space; GO:0005783 endoplasmic reticulum; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044432 endoplasmic reticulum part; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ","K20723","RTN3; reticulon-3","hsa05010 Alzheimer's disease - Homo sapiens (human); ","IPR003388; ","Reticulon; \r"]
["O95202","Mitochondrial proton/calcium exchanger protein OS=Homo sapiens OX=9606 GN=LETM1","LETM1",83.353,82.664,17.9,10,15,10,0.97,0.92,0.914,1.108,1.057,1.071,1.154,3.64E-3,"mitochondria\r","GO:0042407 cristae formation; GO:0016043 cellular component organization; GO:0065008 regulation of biological quality; GO:0050801 ion homeostasis; GO:0007006 mitochondrial membrane organization; GO:0030003 cellular cation homeostasis; GO:0098771 inorganic ion homeostasis; GO:0044763 single-organism cellular process; GO:0019725 cellular homeostasis; GO:0044802 single-organism membrane organization; GO:0044699 single-organism process; GO:0055082 cellular chemical homeostasis; GO:0007007 inner mitochondrial membrane organization; GO:0042592 homeostatic process; GO:1902589 single-organism organelle organization; GO:0055080 cation homeostasis; GO:0006873 cellular ion homeostasis; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0007005 mitochondrion organization; GO:0055065 metal ion homeostasis; GO:0006875 cellular metal ion homeostasis; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044429 mitochondrial part; GO:0031090 organelle membrane; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0005740 mitochondrial envelope; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0031975 envelope; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0043022 ribosome binding; GO:0005488 binding; GO:0043167 ion binding; GO:0044877 macromolecular complex binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0005509 calcium ion binding; GO:0043021 ribonucleoprotein complex binding; ","K17800",null,null,"IPR033122; IPR011992; IPR002048; IPR011685; ","Letm1 ribosome-binding domain; EF-hand domain pair; EF-hand domain; LETM1-like; \r"]
["O95208","Epsin-2 OS=Homo sapiens OX=9606 GN=EPN2","EPN2",68.481,4.2717,4.5,3,3,3,1.055,0.981,0.992,1.025,1.063,0.896,0.985,0.782,"nucleus\r","GO:0006810 transport; GO:0016043 cellular component organization; GO:0016192 vesicle-mediated transport; GO:0061024 membrane organization; GO:0051179 localization; GO:0006897 endocytosis; GO:0009987 cellular process; GO:0051234 establishment of localization; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0045334 clathrin-coated endocytic vesicle; GO:0031410 cytoplasmic vesicle; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0030669 clathrin-coated endocytic vesicle membrane; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0030120 vesicle coat; GO:0005623 cell; GO:0044422 organelle part; GO:0030662 coated vesicle membrane; GO:0030136 clathrin-coated vesicle; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0030139 endocytic vesicle; GO:0043227 membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0030666 endocytic vesicle membrane; GO:0048475 coated membrane; GO:0044446 intracellular organelle part; GO:0012506 vesicle membrane; GO:0005829 cytosol; GO:0030665 clathrin-coated vesicle membrane; GO:0030135 coated vesicle; GO:0030128 clathrin coat of endocytic vesicle; GO:0030659 cytoplasmic vesicle membrane; GO:0030125 clathrin vesicle coat; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0030118 clathrin coat; GO:0030117 membrane coat; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0008289 lipid binding; GO:0050839 cell adhesion molecule binding; GO:0005515 protein binding; GO:0005488 binding; GO:0045296 cadherin binding; ","K12471","EPN; epsin","hsa04144 Endocytosis - Homo sapiens (human); ","IPR013809; IPR008942; ","ENTH  domain; ENTH/VHS; \r"]
["O95218","Zinc finger Ran-binding domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ZRANB2","ZRANB2",37.404,3.1674,3.3,1,1,1,0.915,0.958,0.878,1.135,1.01,1.105,1.181,0.0186,"nucleus\r","GO:0050794 regulation of cellular process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0006396 RNA processing; GO:0010468 regulation of gene expression; GO:0006355 regulation of transcription, DNA-templated; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0010467 gene expression; GO:0016071 mRNA metabolic process; GO:0065007 biological regulation; GO:2000112 regulation of cellular macromolecule biosynthetic process; ","GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0046914 transition metal ion binding; GO:0005488 binding; GO:0001071 nucleic acid binding transcription factor activity; GO:0043167 ion binding; GO:0003676 nucleic acid binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0008270 zinc ion binding; GO:0003700 transcription factor activity, sequence-specific DNA binding; ",{"$nulls":3},"IPR001876; ","\"Zinc finger, RanBP2-type; \"\r"]
["O95232","Luc7-like protein 3 OS=Homo sapiens OX=9606 GN=LUC7L3","LUC7L3",51.466,6.3857,4.4,2,3,2,1.034,0.981,1.001,0.968,1.011,1.013,0.992,0.727,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0006376 mRNA splice site selection; GO:0016043 cellular component organization; GO:0022613 ribonucleoprotein complex biogenesis; GO:0022618 ribonucleoprotein complex assembly; GO:0006725 cellular aromatic compound metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0008152 metabolic process; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0071826 ribonucleoprotein complex subunit organization; GO:0046483 heterocycle metabolic process; GO:0022607 cellular component assembly; GO:0006139 nucleobase-containing compound metabolic process; GO:0065003 macromolecular complex assembly; GO:0000375 RNA splicing, via transesterification reactions; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0006396 RNA processing; GO:0034622 cellular macromolecular complex assembly; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0044238 primary metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:0090304 nucleic acid metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0000245 spliceosomal complex assembly; GO:0016071 mRNA metabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0005685 U1 snRNP; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0005684 U2-type spliceosomal complex; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005681 spliceosomal complex; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0097525 spliceosomal snRNP complex; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0044464 cell part; GO:0005622 intracellular; GO:0071010 prespliceosome; GO:0071004 U2-type prespliceosome; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0030532 small nuclear ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003677 DNA binding; GO:0003729 mRNA binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; "]
["O95248","Myotubularin-related protein 5 OS=Homo sapiens OX=9606 GN=SBF1","SBF1",208.44,20.387,3.3,6,6,6,0.969,1.069,0.948,0.959,0.999,1.006,0.993,0.883,"nucleus\r","GO:0000003 reproduction; GO:0016043 cellular component organization; GO:0022414 reproductive process; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0051345 positive regulation of hydrolase activity; GO:0044702 single organism reproductive process; GO:0044093 positive regulation of molecular function; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009987 cellular process; GO:0048232 male gamete generation; GO:0043547 positive regulation of GTPase activity; GO:0007283 spermatogenesis; GO:0019953 sexual reproduction; GO:0044238 primary metabolic process; GO:0006470 protein dephosphorylation; GO:0032501 multicellular organismal process; GO:0016311 dephosphorylation; GO:0051704 multi-organism process; GO:0007276 gamete generation; GO:0043085 positive regulation of catalytic activity; GO:0032504 multicellular organism reproduction; GO:0051336 regulation of hydrolase activity; GO:0006793 phosphorus metabolic process; GO:0050790 regulation of catalytic activity; GO:0044703 multi-organism reproductive process; GO:0061024 membrane organization; GO:0044260 cellular macromolecule metabolic process; GO:0065009 regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0006464 cellular protein modification process; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:0048609 multicellular organismal reproductive process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0043229 intracellular organelle; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0030234 enzyme regulator activity; GO:0003824 catalytic activity; GO:0042578 phosphoric ester hydrolase activity; GO:0017112 Rab guanyl-nucleotide exchange factor activity; GO:0005085 guanyl-nucleotide exchange factor activity; GO:0016791 phosphatase activity; GO:0019208 phosphatase regulator activity; GO:0016788 hydrolase activity, acting on ester bonds; GO:0016787 hydrolase activity; GO:0005088 Ras guanyl-nucleotide exchange factor activity; GO:0004721 phosphoprotein phosphatase activity; GO:0008138 protein tyrosine/serine/threonine phosphatase activity; GO:0098772 molecular function regulator; ","K18061",null,null,"IPR022096; IPR005112; IPR010569; IPR001849; IPR029021; IPR005113; IPR001194; IPR011993; IPR004182; ","SBF1/SBF2 domain; dDENN domain; Myotubularin-like phosphatase domain; Pleckstrin homology domain; Protein-tyrosine phosphatase-like; uDENN domain; DENN domain; PH domain-like; GRAM domain; \r"]
["O95260","Arginyl-tRNA--protein transferase 1 OS=Homo sapiens OX=9606 GN=ATE1","ATE1",59.09,14.814,6.8,2,3,2,0.996,1.005,1.008,1.032,0.97,0.998,0.997,0.865,"cytoplasm\r","GO:0016598 protein arginylation; GO:0043632 modification-dependent macromolecule catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0019941 modification-dependent protein catabolic process; GO:0044267 cellular protein metabolic process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:1901575 organic substance catabolic process; GO:0008152 metabolic process; GO:0030163 protein catabolic process; GO:0009057 macromolecule catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0044248 cellular catabolic process; GO:0006464 cellular protein modification process; GO:0006508 proteolysis; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:0009987 cellular process; GO:0009056 catabolic process; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; ","GO:0016746 transferase activity, transferring acyl groups; GO:0003824 catalytic activity; GO:0005488 binding; GO:0005515 protein binding; GO:0016740 transferase activity; GO:0016755 transferase activity, transferring amino-acyl groups; GO:0004057 arginyltransferase activity; ","K00685",null,null,"IPR007471; IPR016181; IPR007472; ","\"Arginine-tRNA-protein transferase, N-terminal; Acyl-CoA N-acyltransferase; Arginine-tRNA-protein transferase, C-terminal; \"\r"]
["O95274","Ly6/PLAUR domain-containing protein 3 OS=Homo sapiens OX=9606 GN=LYPD3","LYPD3",35.97,22.598,19.4,6,8,6,0.798,0.832,0.698,1.297,1.158,1.203,1.571,1.92E-3,"extracellular\r","GO:0043687 post-translational protein modification; GO:0006501 C-terminal protein lipidation; GO:0044267 cellular protein metabolic process; GO:0009058 biosynthetic process; GO:0018410 C-terminal protein amino acid modification; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044237 cellular metabolic process; GO:0044249 cellular biosynthetic process; GO:0042157 lipoprotein metabolic process; GO:0071704 organic substance metabolic process; GO:0022610 biological adhesion; GO:0008152 metabolic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0031589 cell-substrate adhesion; GO:0007160 cell-matrix adhesion; GO:0044260 cellular macromolecule metabolic process; GO:0007155 cell adhesion; GO:0006464 cellular protein modification process; GO:0006497 protein lipidation; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:0009987 cellular process; GO:0042158 lipoprotein biosynthetic process; ","GO:0016020 membrane; GO:0031226 intrinsic component of plasma membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0044459 plasma membrane part; GO:0044464 cell part; GO:0071944 cell periphery; GO:0044425 membrane part; GO:0031225 anchored component of membrane; GO:0031224 intrinsic component of membrane; GO:0005623 cell; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0046658 anchored component of plasma membrane; GO:0005886 plasma membrane; ","GO:0005515 protein binding; GO:0043236 laminin binding; GO:0005488 binding; GO:0050840 extracellular matrix binding; ",{"$nulls":3},"IPR016054; ","Ly-6 antigen/uPA receptor-like; \r"]
["O95292","Vesicle-associated membrane protein-associated protein B/C OS=Homo sapiens OX=9606 GN=VAPB","VAPB",27.228,19.728,22.6,6,10,5,1.018,1.053,1.064,0.962,0.957,0.977,0.924,0.00578,"cytoplasm\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0044827 modulation by host of viral genome replication; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0008610 lipid biosynthetic process; GO:0008152 metabolic process; GO:0035966 response to topologically incorrect protein; GO:0030148 sphingolipid biosynthetic process; GO:0044093 positive regulation of molecular function; GO:0044003 modification by symbiont of host morphology or physiology; GO:0055065 metal ion homeostasis; GO:0044789 modulation by host of viral release from host cell; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0051347 positive regulation of transferase activity; GO:0044419 interspecies interaction between organisms; GO:0042325 regulation of phosphorylation; GO:0044794 positive regulation by host of viral process; GO:0051716 cellular response to stimulus; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0031323 regulation of cellular metabolic process; GO:0006874 cellular calcium ion homeostasis; GO:0051704 multi-organism process; GO:0006810 transport; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0033554 cellular response to stress; GO:0034976 response to endoplasmic reticulum stress; GO:0044793 negative regulation by host of viral process; GO:0031399 regulation of protein modification process; GO:0032075 positive regulation of nuclease activity; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0051817 modification of morphology or physiology of other organism involved in symbiotic interaction; GO:1903901 negative regulation of viral life cycle; GO:0032069 regulation of nuclease activity; GO:0051345 positive regulation of hydrolase activity; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0051702 interaction with symbiont; GO:0048878 chemical homeostasis; GO:0006986 response to unfolded protein; GO:0006950 response to stress; GO:0044711 single-organism biosynthetic process; GO:0090114 COPII-coated vesicle budding; GO:0016192 vesicle-mediated transport; GO:0043900 regulation of multi-organism process; GO:1902188 positive regulation of viral release from host cell; GO:0045071 negative regulation of viral genome replication; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:1902186 regulation of viral release from host cell; GO:0051247 positive regulation of protein metabolic process; GO:0006873 cellular ion homeostasis; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0061024 membrane organization; GO:0006900 membrane budding; GO:0046719 regulation by virus of viral protein levels in host cell; GO:0051179 localization; GO:1901564 organonitrogen compound metabolic process; GO:0010256 endomembrane system organization; GO:0072503 cellular divalent inorganic cation homeostasis; GO:0040017 positive regulation of locomotion; GO:0006643 membrane lipid metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044830 modulation by host of viral RNA genome replication; GO:0044764 multi-organism cellular process; GO:0035821 modification of morphology or physiology of other organism; GO:0046725 negative regulation by virus of viral protein levels in host cell; GO:0030968 endoplasmic reticulum unfolded protein response; GO:0044068 modulation by symbiont of host cellular process; GO:0051234 establishment of localization; GO:0040013 negative regulation of locomotion; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0006665 sphingolipid metabolic process; GO:0033674 positive regulation of kinase activity; GO:0070887 cellular response to chemical stimulus; GO:0006629 lipid metabolic process; GO:0048525 negative regulation of viral process; GO:1903902 positive regulation of viral life cycle; GO:0043902 positive regulation of multi-organism process; GO:0045937 positive regulation of phosphate metabolic process; GO:0050801 ion homeostasis; GO:0055074 calcium ion homeostasis; GO:0098771 inorganic ion homeostasis; GO:0019725 cellular homeostasis; GO:0048522 positive regulation of cellular process; GO:0045069 regulation of viral genome replication; GO:0023052 signaling; GO:0044788 modulation by host of viral process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0019054 modulation by virus of host process; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044791 positive regulation by host of viral release from host cell; GO:0019220 regulation of phosphate metabolic process; GO:0072507 divalent inorganic cation homeostasis; GO:0051851 modification by host of symbiont morphology or physiology; GO:0043549 regulation of kinase activity; GO:0007029 endoplasmic reticulum organization; GO:0045859 regulation of protein kinase activity; GO:0016043 cellular component organization; GO:0035967 cellular response to topologically incorrect protein; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0060255 regulation of macromolecule metabolic process; GO:0030003 cellular cation homeostasis; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0048193 Golgi vesicle transport; GO:0050896 response to stimulus; GO:1901566 organonitrogen compound biosynthetic process; GO:0055082 cellular chemical homeostasis; GO:0044790 negative regulation by host of viral release from host cell; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0055080 cation homeostasis; GO:0016032 viral process; GO:0009987 cellular process; GO:0045070 positive regulation of viral genome replication; GO:0046467 membrane lipid biosynthetic process; GO:0034620 cellular response to unfolded protein; GO:0001932 regulation of protein phosphorylation; GO:0050792 regulation of viral process; GO:0031401 positive regulation of protein modification process; GO:0006807 nitrogen compound metabolic process; GO:0016050 vesicle organization; GO:0044829 positive regulation by host of viral genome replication; GO:0051701 interaction with host; GO:0006987 activation of signaling protein activity involved in unfolded protein response; GO:0001934 positive regulation of protein phosphorylation; GO:0045860 positive regulation of protein kinase activity; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0043085 positive regulation of catalytic activity; GO:0043901 negative regulation of multi-organism process; GO:0051641 cellular localization; GO:0044828 negative regulation by host of viral genome replication; GO:0048524 positive regulation of viral process; GO:1902187 negative regulation of viral release from host cell; GO:0051246 regulation of protein metabolic process; GO:0006875 cellular metal ion homeostasis; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0040012 regulation of locomotion; GO:1903900 regulation of viral life cycle; GO:0019048 modulation by virus of host morphology or physiology; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0098588 bounding membrane of organelle; GO:0031090 organelle membrane; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0000139 Golgi membrane; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044432 endoplasmic reticulum part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0044431 Golgi apparatus part; GO:0005794 Golgi apparatus; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; ","GO:0050839 cell adhesion molecule binding; GO:0042802 identical protein binding; GO:0008092 cytoskeletal protein binding; GO:0046982 protein heterodimerization activity; GO:0042803 protein homodimerization activity; GO:0008017 microtubule binding; GO:0005488 binding; GO:0033149 FFAT motif binding; GO:0046983 protein dimerization activity; GO:0045296 cadherin binding; GO:0015631 tubulin binding; GO:0019904 protein domain specific binding; GO:0005515 protein binding; GO:0048487 beta-tubulin binding; GO:0019899 enzyme binding; ","K10707","VAPB; vesicle-associated membrane protein-associated protein B","hsa04979 Cholesterol metabolism - Homo sapiens (human); ","IPR008962; IPR000535; ","PapD-like; Major sperm protein (MSP) domain; \r"]
["O95294","RasGAP-activating-like protein 1 OS=Homo sapiens OX=9606 GN=RASAL1","RASAL1",90.015,5.8479,2.5,2,2,2,0.975,1.079,1.015,1.084,0.96,0.904,0.961,0.527,"nucleus\r","GO:0044700 single organism signaling; GO:0045666 positive regulation of neuron differentiation; GO:0009968 negative regulation of signal transduction; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0045927 positive regulation of growth; GO:0051130 positive regulation of cellular component organization; GO:0001558 regulation of cell growth; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0051240 positive regulation of multicellular organismal process; GO:0044093 positive regulation of molecular function; GO:1903861 positive regulation of dendrite extension; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0010720 positive regulation of cell development; GO:0051056 regulation of small GTPase mediated signal transduction; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0048639 positive regulation of developmental growth; GO:0030307 positive regulation of cell growth; GO:0048699 generation of neurons; GO:0031346 positive regulation of cell projection organization; GO:0051962 positive regulation of nervous system development; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0000165 MAPK cascade; GO:1903859 regulation of dendrite extension; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:1902532 negative regulation of intracellular signal transduction; GO:0045664 regulation of neuron differentiation; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0043087 regulation of GTPase activity; GO:0065009 regulation of molecular function; GO:0006464 cellular protein modification process; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0051094 positive regulation of developmental process; GO:0010975 regulation of neuron projection development; GO:2000026 regulation of multicellular organismal development; GO:0050794 regulation of cellular process; GO:0016310 phosphorylation; GO:0044707 single-multicellular organism process; GO:0040008 regulation of growth; GO:0044267 cellular protein metabolic process; GO:0031344 regulation of cell projection organization; GO:0046578 regulation of Ras protein signal transduction; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0048638 regulation of developmental growth; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:0045597 positive regulation of cell differentiation; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0006468 protein phosphorylation; GO:0051345 positive regulation of hydrolase activity; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0023014 signal transduction by protein phosphorylation; GO:0046580 negative regulation of Ras protein signal transduction; GO:1902531 regulation of intracellular signal transduction; GO:0035556 intracellular signal transduction; GO:0043547 positive regulation of GTPase activity; GO:0048731 system development; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0048585 negative regulation of response to stimulus; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0010976 positive regulation of neuron projection development; GO:0006793 phosphorus metabolic process; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0050769 positive regulation of neurogenesis; GO:0051128 regulation of cellular component organization; GO:0043412 macromolecule modification; GO:0050793 regulation of developmental process; GO:0022604 regulation of cell morphogenesis; GO:0051058 negative regulation of small GTPase mediated signal transduction; GO:0050767 regulation of neurogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0031226 intrinsic component of plasma membrane; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0009898 cytoplasmic side of plasma membrane; GO:0098562 cytoplasmic side of membrane; GO:0005886 plasma membrane; GO:0044459 plasma membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane; GO:0044444 cytoplasmic part; GO:0098552 side of membrane; ","GO:0030234 enzyme regulator activity; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0005488 binding; GO:0030695 GTPase regulator activity; GO:0005543 phospholipid binding; GO:0043167 ion binding; GO:0008289 lipid binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0043168 anion binding; GO:0098772 molecular function regulator; GO:0008047 enzyme activator activity; GO:0005096 GTPase activator activity; ","K17632","RASAL1; RAS protein activator-like 1","hsa04014 Ras signaling pathway - Homo sapiens (human); ","IPR001936; IPR011993; IPR008936; IPR000008; IPR001849; ","Ras GTPase-activating protein; PH domain-like; Rho GTPase activation protein; C2 domain; Pleckstrin homology domain; \r"]
["O95295","SNARE-associated protein Snapin OS=Homo sapiens OX=9606 GN=SNAPIN","SNAPIN",14.874,21.718,26.5,3,4,3,1.027,1.063,0.918,1.008,1.026,0.971,0.999,0.989,"cytoplasm\r","GO:0044700 single organism signaling; GO:0021700 developmental maturation; GO:0065008 regulation of biological quality; GO:0030641 regulation of cellular pH; GO:0030004 cellular monovalent inorganic cation homeostasis; GO:0007269 neurotransmitter secretion; GO:0008090 retrograde axonal transport; GO:0006914 autophagy; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0099003 vesicle-mediated transport in synapse; GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane; GO:0008152 metabolic process; GO:0032879 regulation of localization; GO:0099517 synaptic vesicle transport along microtubule; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0008104 protein localization; GO:0044801 single-organism membrane fusion; GO:0008089 anterograde axonal transport; GO:0099500 vesicle fusion to plasma membrane; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0007399 nervous system development; GO:0048489 synaptic vesicle transport; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0061025 membrane fusion; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0016188 synaptic vesicle maturation; GO:0008333 endosome to lysosome transport; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0050768 negative regulation of neurogenesis; GO:0006810 transport; GO:0007267 cell-cell signaling; GO:0045665 negative regulation of neuron differentiation; GO:0006906 vesicle fusion; GO:0045026 plasma membrane fusion; GO:0010721 negative regulation of cell development; GO:0010975 regulation of neuron projection development; GO:0099643 signal release from synapse; GO:0050794 regulation of cellular process; GO:0051640 organelle localization; GO:0044707 single-multicellular organism process; GO:0090174 organelle membrane fusion; GO:0046907 intracellular transport; GO:0006885 regulation of pH; GO:0099514 synaptic vesicle cytoskeletal transport; GO:0007035 vacuolar acidification; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0051239 regulation of multicellular organismal process; GO:0030705 cytoskeleton-dependent intracellular transport; GO:1903335 regulation of vacuolar transport; GO:0034629 cellular protein complex localization; GO:1902578 single-organism localization; GO:0031345 negative regulation of cell projection organization; GO:0044248 cellular catabolic process; GO:1902580 single-organism cellular localization; GO:0007275 multicellular organism development; GO:0007042 lysosomal lumen acidification; GO:0034613 cellular protein localization; GO:0048878 chemical homeostasis; GO:0048731 system development; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0016192 vesicle-mediated transport; GO:0098930 axonal transport; GO:0016079 synaptic vesicle exocytosis; GO:0010977 negative regulation of neuron projection development; GO:0071702 organic substance transport; GO:0023061 signal release; GO:0048284 organelle fusion; GO:1902824 positive regulation of late endosome to lysosome transport; GO:0044238 primary metabolic process; GO:0051656 establishment of organelle localization; GO:0050808 synapse organization; GO:0007017 microtubule-based process; GO:0097480 establishment of synaptic vesicle localization; GO:0045184 establishment of protein localization; GO:0030182 neuron differentiation; GO:0045055 regulated exocytosis; GO:0099536 synaptic signaling; GO:0051453 regulation of intracellular pH; GO:0006873 cellular ion homeostasis; GO:0097576 vacuole fusion; GO:0097479 synaptic vesicle localization; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0043473 pigmentation; GO:0080171 lytic vacuole organization; GO:0006928 movement of cell or subcellular component; GO:0007268 chemical synaptic transmission; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0033059 cellular pigmentation; GO:0006887 exocytosis; GO:0051093 negative regulation of developmental process; GO:0001505 regulation of neurotransmitter levels; GO:0035751 regulation of lysosomal lumen pH; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0051129 negative regulation of cellular component organization; GO:0022008 neurogenesis; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0099504 synaptic vesicle cycle; GO:0051234 establishment of localization; GO:0010970 transport along microtubule; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0007033 vacuole organization; GO:0098916 anterograde trans-synaptic signaling; GO:0045596 negative regulation of cell differentiation; GO:0033036 macromolecule localization; GO:0032438 melanosome organization; GO:0072553 terminal button organization; GO:0016236 macroautophagy; GO:0032502 developmental process; GO:0051650 establishment of vesicle localization; GO:0050801 ion homeostasis; GO:0051098 regulation of binding; GO:0098771 inorganic ion homeostasis; GO:0019725 cellular homeostasis; GO:0023052 signaling; GO:1902582 single-organism intracellular transport; GO:0051050 positive regulation of transport; GO:0007040 lysosome organization; GO:0016197 endosomal transport; GO:1902589 single-organism organelle organization; GO:0008088 axo-dendritic transport; GO:0099518 vesicle cytoskeletal trafficking; GO:0050789 regulation of biological process; GO:0030030 cell projection organization; GO:0045664 regulation of neuron differentiation; GO:0032940 secretion by cell; GO:1902822 regulation of late endosome to lysosome transport; GO:0065009 regulation of molecular function; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0031503 protein complex localization; GO:0072384 organelle transport along microtubule; GO:1903337 positive regulation of vacuolar transport; GO:0016043 cellular component organization; GO:0045851 pH reduction; GO:0030003 cellular cation homeostasis; GO:0097352 autophagosome maturation; GO:0031344 regulation of cell projection organization; GO:0048490 anterograde synaptic vesicle transport; GO:0099531 presynaptic process involved in chemical synaptic transmission; GO:1902774 late endosome to lysosome transport; GO:0048468 cell development; GO:0099111 microtubule-based transport; GO:0055082 cellular chemical homeostasis; GO:0071704 organic substance metabolic process; GO:0043393 regulation of protein binding; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:0051961 negative regulation of nervous system development; GO:0055080 cation homeostasis; GO:0045324 late endosome to vacuole transport; GO:0016032 viral process; GO:0051648 vesicle localization; GO:0006886 intracellular protein transport; GO:0099537 trans-synaptic signaling; GO:0009987 cellular process; GO:0032418 lysosome localization; GO:0045595 regulation of cell differentiation; GO:0007041 lysosomal transport; GO:0055067 monovalent inorganic cation homeostasis; GO:0048753 pigment granule organization; GO:0051049 regulation of transport; GO:0017156 calcium ion regulated exocytosis; GO:0016050 vesicle organization; GO:0044802 single-organism membrane organization; GO:0031175 neuron projection development; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0047496 vesicle transport along microtubule; GO:0007018 microtubule-based movement; GO:0070727 cellular macromolecule localization; GO:0044767 single-organism developmental process; GO:0007034 vacuolar transport; GO:0010467 gene expression; GO:0051128 regulation of cellular component organization; GO:0051452 intracellular pH reduction; GO:0051604 protein maturation; GO:0009056 catabolic process; GO:0006836 neurotransmitter transport; GO:0050767 regulation of neurogenesis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0030658 transport vesicle membrane; GO:0016020 membrane; GO:0031082 BLOC complex; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0030054 cell junction; GO:0099568 cytoplasmic region; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0032838 cell projection cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0099501 exocytic vesicle membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0070382 exocytic vesicle; GO:0005765 lysosomal membrane; GO:0008021 synaptic vesicle; GO:0098793 presynapse; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0098805 whole membrane; GO:0005764 lysosome; GO:0043005 neuron projection; GO:0044431 Golgi apparatus part; GO:0048471 perinuclear region of cytoplasm; GO:0044445 cytosolic part; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0044456 synapse part; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0042995 cell projection; GO:0099078 BORC complex; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0044463 cell projection part; GO:0030672 synaptic vesicle membrane; GO:0005829 cytosol; GO:0033267 axon part; GO:0045202 synapse; GO:0030659 cytoplasmic vesicle membrane; GO:0098852 lytic vacuole membrane; GO:0030424 axon; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031083 BLOC-1 complex; GO:1904115 axon cytoplasm; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0005794 Golgi apparatus; GO:0043234 protein complex; GO:0030133 transport vesicle; GO:0044444 cytoplasmic part; ","GO:0000149 SNARE binding; GO:0005515 protein binding; GO:0005488 binding; ","K20002"]
["O95298","NADH dehydrogenase [ubiquinone] 1 subunit C2 OS=Homo sapiens OX=9606 GN=NDUFC2","NDUFC2",14.187,5.8538,16.8,2,2,2,1.113,0.974,1.069,0.946,0.947,0.963,0.905,0.133,"cyto_nucl\r","GO:0044085 cellular component biogenesis; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0045321 leukocyte activation; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0022607 cellular component assembly; GO:0006753 nucleoside phosphate metabolic process; GO:0065003 macromolecular complex assembly; GO:0007005 mitochondrion organization; GO:0019693 ribose phosphate metabolic process; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0002443 leukocyte mediated immunity; GO:0071822 protein complex subunit organization; GO:0010257 NADH dehydrogenase complex assembly; GO:0055114 oxidation-reduction process; GO:0002446 neutrophil mediated immunity; GO:0044281 small molecule metabolic process; GO:0006119 oxidative phosphorylation; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0006120 mitochondrial electron transport, NADH to ubiquinone; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0006810 transport; GO:0097031 mitochondrial respiratory chain complex I biogenesis; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0032940 secretion by cell; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0022900 electron transport chain; GO:0043299 leukocyte degranulation; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0070271 protein complex biogenesis; GO:0033108 mitochondrial respiratory chain complex assembly; GO:0016043 cellular component organization; GO:0016310 phosphorylation; GO:0002283 neutrophil activation involved in immune response; GO:0006725 cellular aromatic compound metabolic process; GO:0002252 immune effector process; GO:0042773 ATP synthesis coupled electron transport; GO:0009259 ribonucleotide metabolic process; GO:0022904 respiratory electron transport chain; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0032981 mitochondrial respiratory chain complex I assembly; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0036230 granulocyte activation; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0009119 ribonucleoside metabolic process; GO:0006461 protein complex assembly; GO:0043623 cellular protein complex assembly; GO:0046034 ATP metabolic process; GO:0034622 cellular macromolecular complex assembly; GO:0016192 vesicle-mediated transport; GO:0006807 nitrogen compound metabolic process; GO:0002376 immune system process; GO:0009141 nucleoside triphosphate metabolic process; GO:0043312 neutrophil degranulation; GO:0044238 primary metabolic process; GO:0002263 cell activation involved in immune response; GO:0045333 cellular respiration; GO:0006163 purine nucleotide metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0002366 leukocyte activation involved in immune response; GO:0046128 purine ribonucleoside metabolic process; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0001775 cell activation; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0051179 localization; GO:0006955 immune response; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:0006887 exocytosis; GO:1901564 organonitrogen compound metabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0031224 intrinsic component of membrane; GO:0045271 respiratory chain complex I; GO:0032991 macromolecular complex; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0005747 mitochondrial respiratory chain complex I; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0005765 lysosomal membrane; GO:1902494 catalytic complex; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:0098805 whole membrane; GO:0019866 organelle inner membrane; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0098803 respiratory chain complex; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0044429 mitochondrial part; GO:0098588 bounding membrane of organelle; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0035577 azurophil granule membrane; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0016021 integral component of membrane; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0005746 mitochondrial respiratory chain; GO:0042582 azurophil granule; GO:0098852 lytic vacuole membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0030667 secretory granule membrane; GO:0030964 NADH dehydrogenase complex; GO:0005766 primary lysosome; GO:0031975 envelope; GO:1990204 oxidoreductase complex; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0043234 protein complex; GO:0031966 mitochondrial membrane; GO:0070469 respiratory chain; GO:0044444 cytoplasmic part; ","GO:0050136 NADH dehydrogenase (quinone) activity; GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:0003954 NADH dehydrogenase activity; GO:0003824 catalytic activity; GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; GO:0008137 NADH dehydrogenase (ubiquinone) activity; GO:0016491 oxidoreductase activity; ","K03968","NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2","hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); "]
["O95299","NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFA10","NDUFA10",40.75,10.158,10.4,4,8,4,1.008,1.052,0.979,0.968,0.968,1.021,0.973,0.377,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0022607 cellular component assembly; GO:0006753 nucleoside phosphate metabolic process; GO:0065003 macromolecular complex assembly; GO:0007005 mitochondrion organization; GO:0019693 ribose phosphate metabolic process; GO:0071822 protein complex subunit organization; GO:0010257 NADH dehydrogenase complex assembly; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0006119 oxidative phosphorylation; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0006120 mitochondrial electron transport, NADH to ubiquinone; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0097031 mitochondrial respiratory chain complex I biogenesis; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0022900 electron transport chain; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0070271 protein complex biogenesis; GO:0033108 mitochondrial respiratory chain complex assembly; GO:0016043 cellular component organization; GO:0016310 phosphorylation; GO:0006725 cellular aromatic compound metabolic process; GO:0042773 ATP synthesis coupled electron transport; GO:0009259 ribonucleotide metabolic process; GO:0022904 respiratory electron transport chain; GO:0071704 organic substance metabolic process; GO:0032981 mitochondrial respiratory chain complex I assembly; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0009119 ribonucleoside metabolic process; GO:0006461 protein complex assembly; GO:0043623 cellular protein complex assembly; GO:0046034 ATP metabolic process; GO:0034622 cellular macromolecular complex assembly; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0045333 cellular respiration; GO:0006163 purine nucleotide metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0046128 purine ribonucleoside metabolic process; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:1901564 organonitrogen compound metabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0045271 respiratory chain complex I; GO:0032991 macromolecular complex; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0005747 mitochondrial respiratory chain complex I; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0043209 myelin sheath; GO:0044464 cell part; GO:0005622 intracellular; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0098803 respiratory chain complex; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005759 mitochondrial matrix; GO:0044429 mitochondrial part; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005739 mitochondrion; GO:0005746 mitochondrial respiratory chain; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0030964 NADH dehydrogenase complex; GO:0031975 envelope; GO:1990204 oxidoreductase complex; GO:0043234 protein complex; GO:0031966 mitochondrial membrane; GO:0070469 respiratory chain; GO:0044444 cytoplasmic part; ","GO:0050136 NADH dehydrogenase (quinone) activity; GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:0003954 NADH dehydrogenase activity; GO:0003824 catalytic activity; GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; GO:0008137 NADH dehydrogenase (ubiquinone) activity; GO:0016491 oxidoreductase activity; ","K03954","NDUFA10; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10","hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); ","IPR027417; IPR031314; ","P-loop containing nucleoside triphosphate hydrolase; Deoxynucleoside kinase domain; \r"]
["O95302","Peptidyl-prolyl cis-trans isomerase FKBP9 OS=Homo sapiens OX=9606 GN=FKBP9","FKBP9",63.083,52.348,21.4,12,19,11,1.154,1.107,1.107,0.861,0.889,0.858,0.774,0.000139,"extracellular\r","GO:0061077 chaperone-mediated protein folding; GO:0044267 cellular protein metabolic process; GO:0044238 primary metabolic process; GO:0018208 peptidyl-proline modification; GO:0000413 protein peptidyl-prolyl isomerization; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0006457 protein folding; GO:0018193 peptidyl-amino acid modification; GO:0008152 metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:0009987 cellular process; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005783 endoplasmic reticulum; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003755 peptidyl-prolyl cis-trans isomerase activity; GO:0016853 isomerase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0008144 drug binding; GO:0005509 calcium ion binding; GO:0005528 FK506 binding; GO:0005527 macrolide binding; GO:0016859 cis-trans isomerase activity; ","K09575",null,null,"IPR011992; IPR002048; IPR001179; ","EF-hand domain pair; EF-hand domain; FKBP-type peptidyl-prolyl cis-trans isomerase domain; \r"]
["O95336","6-phosphogluconolactonase OS=Homo sapiens OX=9606 GN=PGLS","PGLS",27.547,34.798,35.3,8,19,8,1.018,0.996,0.976,0.991,1.016,1.018,1.012,0.477,"extracellular\r","GO:0006739 NADP metabolic process; GO:0019362 pyridine nucleotide metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0046496 nicotinamide nucleotide metabolic process; GO:0009051 pentose-phosphate shunt, oxidative branch; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0072524 pyridine-containing compound metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0051156 glucose 6-phosphate metabolic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0019682 glyceraldehyde-3-phosphate metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0006098 pentose-phosphate shunt; GO:0019693 ribose phosphate metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006081 cellular aldehyde metabolic process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0006732 coenzyme metabolic process; GO:0005975 carbohydrate metabolic process; GO:0044238 primary metabolic process; GO:0051186 cofactor metabolic process; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0019637 organophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0017057 6-phosphogluconolactonase activity; GO:0016787 hydrolase activity; GO:0052689 carboxylic ester hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016788 hydrolase activity, acting on ester bonds; ","K01057","PGLS; 6-phosphogluconolactonase [EC:3.1.1.31]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00030 Pentose phosphate pathway - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); ","IPR006148; IPR005900; ","\"Glucosamine/galactosamine-6-phosphate isomerase; 6-phosphogluconolactonase, DevB-type; \"\r"]
["O95347","Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2","SMC2",135.65,5.6794,3.2,3,3,3,0.754,0.746,0.764,1.17,1.221,1.318,1.638,0.000158,"cytoplasm\r","GO:0000003 reproduction; GO:0016043 cellular component organization; GO:1903046 meiotic cell cycle process; GO:0022414 reproductive process; GO:0048285 organelle fission; GO:0007067 mitotic nuclear division; GO:0044699 single-organism process; GO:1903047 mitotic cell cycle process; GO:0030261 chromosome condensation; GO:0000819 sister chromatid segregation; GO:0006323 DNA packaging; GO:0010032 meiotic chromosome condensation; GO:0044702 single organism reproductive process; GO:0009987 cellular process; GO:0045132 meiotic chromosome segregation; GO:0071103 DNA conformation change; GO:0000278 mitotic cell cycle; GO:0007059 chromosome segregation; GO:0071822 protein complex subunit organization; GO:0007076 mitotic chromosome condensation; GO:0044763 single-organism cellular process; GO:0000070 mitotic sister chromatid segregation; GO:0051321 meiotic cell cycle; GO:0043933 macromolecular complex subunit organization; GO:1902589 single-organism organelle organization; GO:0051276 chromosome organization; GO:0006996 organelle organization; GO:0098813 nuclear chromosome segregation; GO:0000280 nuclear division; GO:0070192 chromosome organization involved in meiotic cell cycle; GO:0007126 meiotic nuclear division; GO:0022402 cell cycle process; GO:0051301 cell division; GO:0051383 kinetochore organization; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; ","GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0000793 condensed chromosome; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0000796 condensin complex; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0044815 DNA packaging complex; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0000228 nuclear chromosome; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0046982 protein heterodimerization activity; GO:0046983 protein dimerization activity; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K06674",null,null,"IPR010935; IPR027417; IPR003395; ","\"SMCs flexible hinge; P-loop containing nucleoside triphosphate hydrolase; RecF/RecN/SMC, N-terminal; \"\r"]
["O95352","Ubiquitin-like modifier-activating enzyme ATG7 OS=Homo sapiens OX=9606 GN=ATG7","ATG7",77.959,8.3378,3.4,2,5,2,0.959,0.928,0.944,1.146,1.049,0.979,1.121,0.0733,"cytoplasm\r","GO:0010941 regulation of cell death; GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0032270 positive regulation of cellular protein metabolic process; GO:1901859 negative regulation of mitochondrial DNA metabolic process; GO:0039521 suppression by virus of host autophagy; GO:0098542 defense response to other organism; GO:0039519 modulation by virus of host autophagy; GO:0090329 regulation of DNA-dependent DNA replication; GO:0009749 response to glucose; GO:0006914 autophagy; GO:0010821 regulation of mitochondrion organization; GO:0044237 cellular metabolic process; GO:0042157 lipoprotein metabolic process; GO:0015031 protein transport; GO:0009607 response to biotic stimulus; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0014072 response to isoquinoline alkaloid; GO:0044003 modification by symbiont of host morphology or physiology; GO:0009719 response to endogenous stimulus; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009743 response to carbohydrate; GO:0008104 protein localization; GO:0044419 interspecies interaction between organisms; GO:0044765 single-organism transport; GO:0046903 secretion; GO:1903203 regulation of oxidative stress-induced neuron death; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0060359 response to ammonium ion; GO:0071317 cellular response to isoquinoline alkaloid; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0061025 membrane fusion; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0071242 cellular response to ammonium ion; GO:0031323 regulation of cellular metabolic process; GO:0010506 regulation of autophagy; GO:0051704 multi-organism process; GO:0006810 transport; GO:0010243 response to organonitrogen compound; GO:0080135 regulation of cellular response to stress; GO:0051053 negative regulation of DNA metabolic process; GO:0010508 positive regulation of autophagy; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:0034284 response to monosaccharide; GO:1901698 response to nitrogen compound; GO:0044260 cellular macromolecule metabolic process; GO:1903202 negative regulation of oxidative stress-induced cell death; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006497 protein lipidation; GO:0006464 cellular protein modification process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0060548 negative regulation of cell death; GO:0071312 cellular response to alkaloid; GO:0043068 positive regulation of programmed cell death; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:2000104 negative regulation of DNA-dependent DNA replication; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0009267 cellular response to starvation; GO:0002283 neutrophil activation involved in immune response; GO:0006275 regulation of DNA replication; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:1901700 response to oxygen-containing compound; GO:0043067 regulation of programmed cell death; GO:0043279 response to alkaloid; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0051817 modification of morphology or physiology of other organism involved in symbiotic interaction; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0009889 regulation of biosynthetic process; GO:0009896 positive regulation of catabolic process; GO:0070482 response to oxygen levels; GO:0051171 regulation of nitrogen compound metabolic process; GO:0044248 cellular catabolic process; GO:0042176 regulation of protein catabolic process; GO:0071455 cellular response to hyperoxia; GO:0055093 response to hyperoxia; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:1901215 negative regulation of neuron death; GO:0010823 negative regulation of mitochondrion organization; GO:0016567 protein ubiquitination; GO:0006950 response to stress; GO:0016192 vesicle-mediated transport; GO:0071407 cellular response to organic cyclic compound; GO:0002376 immune system process; GO:0071702 organic substance transport; GO:0071496 cellular response to external stimulus; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0002263 cell activation involved in immune response; GO:0009892 negative regulation of metabolic process; GO:1902617 response to fluoride; GO:1900408 negative regulation of cellular response to oxidative stress; GO:0031668 cellular response to extracellular stimulus; GO:0045184 establishment of protein localization; GO:0031330 negative regulation of cellular catabolic process; GO:0009890 negative regulation of biosynthetic process; GO:0045055 regulated exocytosis; GO:0051247 positive regulation of protein metabolic process; GO:0032446 protein modification by small protein conjugation; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0031325 positive regulation of cellular metabolic process; GO:0001775 cell activation; GO:1902882 regulation of response to oxidative stress; GO:0006955 immune response; GO:0043412 macromolecule modification; GO:0051179 localization; GO:0006887 exocytosis; GO:0001101 response to acid chemical; GO:0009746 response to hexose; GO:0051129 negative regulation of cellular component organization; GO:0031331 positive regulation of cellular catabolic process; GO:0000422 mitophagy; GO:1903008 organelle disassembly; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0035821 modification of morphology or physiology of other organism; GO:0044068 modulation by symbiont of host cellular process; GO:0051234 establishment of localization; GO:1903204 negative regulation of oxidative stress-induced neuron death; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0090296 regulation of mitochondrial DNA replication; GO:0007005 mitochondrion organization; GO:0010035 response to inorganic substance; GO:0033036 macromolecule localization; GO:0042158 lipoprotein biosynthetic process; GO:0070887 cellular response to chemical stimulus; GO:0002274 myeloid leukocyte activation; GO:0016236 macroautophagy; GO:0032502 developmental process; GO:0031326 regulation of cellular biosynthetic process; GO:0043278 response to morphine; GO:0002446 neutrophil mediated immunity; GO:0048522 positive regulation of cellular process; GO:0070647 protein modification by small protein conjugation or removal; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0008156 negative regulation of DNA replication; GO:0010942 positive regulation of cell death; GO:0071417 cellular response to organonitrogen compound; GO:0036296 response to increased oxygen levels; GO:0010639 negative regulation of organelle organization; GO:1902589 single-organism organelle organization; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0051052 regulation of DNA metabolic process; GO:0051607 defense response to virus; GO:1902883 negative regulation of response to oxidative stress; GO:1901699 cellular response to nitrogen compound; GO:0032940 secretion by cell; GO:0007568 aging; GO:0019222 regulation of metabolic process; GO:0019054 modulation by virus of host process; GO:0006952 defense response; GO:0043299 leukocyte degranulation; GO:0010507 negative regulation of autophagy; GO:0036211 protein modification process; GO:0009615 response to virus; GO:0016043 cellular component organization; GO:0036295 cellular response to increased oxygen levels; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0071310 cellular response to organic substance; GO:0043065 positive regulation of apoptotic process; GO:1903201 regulation of oxidative stress-induced cell death; GO:0043207 response to external biotic stimulus; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0031669 cellular response to nutrient levels; GO:0071704 organic substance metabolic process; GO:0009991 response to extracellular stimulus; GO:1901858 regulation of mitochondrial DNA metabolic process; GO:0016032 viral process; GO:0009895 negative regulation of catabolic process; GO:0036230 granulocyte activation; GO:0009059 macromolecule biosynthetic process; GO:0071453 cellular response to oxygen levels; GO:0009987 cellular process; GO:1901214 regulation of neuron death; GO:0044712 single-organism catabolic process; GO:0033043 regulation of organelle organization; GO:0031401 positive regulation of protein modification process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0048585 negative regulation of response to stimulus; GO:0043312 neutrophil degranulation; GO:0051701 interaction with host; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0071315 cellular response to morphine; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0061726 mitochondrion disassembly; GO:0034645 cellular macromolecule biosynthetic process; GO:1900407 regulation of cellular response to oxidative stress; GO:0044767 single-organism developmental process; GO:0071495 cellular response to endogenous stimulus; GO:0051246 regulation of protein metabolic process; GO:0022411 cellular component disassembly; GO:0042594 response to starvation; GO:0051128 regulation of cellular component organization; GO:0031327 negative regulation of cellular biosynthetic process; GO:0045732 positive regulation of protein catabolic process; GO:0031667 response to nutrient levels; GO:0009056 catabolic process; GO:0019048 modulation by virus of host morphology or physiology; GO:0042981 regulation of apoptotic process; GO:0090298 negative regulation of mitochondrial DNA replication; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0044441 ciliary part; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0043005 neuron projection; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0000407 pre-autophagosomal structure; GO:0005930 axoneme; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0005929 cilium; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0097014 ciliary plasm; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0005576 extracellular region; GO:0030424 axon; GO:0043226 organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0044444 cytoplasmic part; ","GO:0008641 small protein activating enzyme activity; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0046983 protein dimerization activity; GO:0004839 ubiquitin activating enzyme activity; GO:0016874 ligase activity; GO:0016877 ligase activity, forming carbon-sulfur bonds; GO:0005515 protein binding; GO:0008134 transcription factor binding; GO:0019778 Atg12 activating enzyme activity; ","K08337","ATG7; ubiquitin-like modifier-activating enzyme ATG7","hsa04216 Ferroptosis - Homo sapiens (human); hsa04136 Autophagy - other - Homo sapiens (human); hsa04140 Autophagy - animal - Homo sapiens (human); ","IPR000594; IPR016040; IPR032197; ","\"THIF-type NAD/FAD binding fold; NAD(P)-binding domain; Ubiquitin-like modifier-activating enzyme Atg7, N-terminal; \"\r"]
["O95359","Transforming acidic coiled-coil-containing protein 2 OS=Homo sapiens OX=9606 GN=TACC2","TACC2",309.42,41.077,5.1,13,16,13,1.004,1.003,0.955,1.01,0.998,1.01,1.019,0.326,"nucleus\r","GO:0032502 developmental process; GO:0021543 pallium development; GO:0007399 nervous system development; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0007420 brain development; GO:0048731 system development; GO:0044699 single-organism process; GO:0008283 cell proliferation; GO:0021987 cerebral cortex development; GO:0032501 multicellular organismal process; GO:0007017 microtubule-based process; GO:0021537 telencephalon development; GO:0000226 microtubule cytoskeleton organization; GO:0048513 animal organ development; GO:0007417 central nervous system development; GO:0044767 single-organism developmental process; GO:0006996 organelle organization; GO:0030900 forebrain development; GO:0060322 head development; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0048856 anatomical structure development; GO:0009987 cellular process; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0071944 cell periphery; GO:0044430 cytoskeletal part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0005886 plasma membrane; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0005856 cytoskeleton; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0005815 microtubule organizing center; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0035257 nuclear hormone receptor binding; GO:0005515 protein binding; GO:0051427 hormone receptor binding; GO:0005102 receptor binding; GO:0005488 binding; ","K14282"]
["O95372","Acyl-protein thioesterase 2 OS=Homo sapiens OX=9606 GN=LYPLA2","LYPLA2",24.737,3.4774,6.9,2,3,2,1.006,0.922,1.017,0.963,1.106,0.987,1.038,0.531,"cyto_nucl\r","GO:0048869 cellular developmental process; GO:0048666 neuron development; GO:0032989 cellular component morphogenesis; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0098734 macromolecule depalmitoylation; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0042157 lipoprotein metabolic process; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0032990 cell part morphogenesis; GO:0048858 cell projection morphogenesis; GO:0032787 monocarboxylic acid metabolic process; GO:0043170 macromolecule metabolic process; GO:0042159 lipoprotein catabolic process; GO:0019538 protein metabolic process; GO:0098732 macromolecule deacylation; GO:0006629 lipid metabolic process; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0002084 protein depalmitoylation; GO:0048699 generation of neurons; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0048812 neuron projection morphogenesis; GO:0006935 chemotaxis; GO:0032501 multicellular organismal process; GO:0000902 cell morphogenesis; GO:1901575 organic substance catabolic process; GO:0042221 response to chemical; GO:0030030 cell projection organization; GO:0035601 protein deacylation; GO:0030163 protein catabolic process; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0042330 taxis; GO:0006464 cellular protein modification process; GO:0040011 locomotion; GO:0036211 protein modification process; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:0043436 oxoacid metabolic process; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0044267 cellular protein metabolic process; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0007411 axon guidance; GO:0071704 organic substance metabolic process; GO:0000904 cell morphogenesis involved in differentiation; GO:0009653 anatomical structure morphogenesis; GO:0030154 cell differentiation; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0007409 axonogenesis; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0048731 system development; GO:0006631 fatty acid metabolic process; GO:0044238 primary metabolic process; GO:0031175 neuron projection development; GO:0061564 axon development; GO:0030182 neuron differentiation; GO:0097485 neuron projection guidance; GO:0044767 single-organism developmental process; GO:0009057 macromolecule catabolic process; GO:0019752 carboxylic acid metabolic process; GO:0006928 movement of cell or subcellular component; GO:0043412 macromolecule modification; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0050839 cell adhesion molecule binding; GO:0098599 palmitoyl hydrolase activity; GO:0052689 carboxylic ester hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0045296 cadherin binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0008474 palmitoyl-(protein) hydrolase activity; GO:0016790 thiolester hydrolase activity; ","K06130","LYPLA2; lysophospholipase II [EC:3.1.1.5]","hsa00564 Glycerophospholipid metabolism - Homo sapiens (human); ","IPR029058; IPR003140; ","Alpha/Beta hydrolase fold; Phospholipase/carboxylesterase/thioesterase; \r"]
["O95373","Importin-7 OS=Homo sapiens OX=9606 GN=IPO7","IPO7",119.52,86.94,11.2,8,13,8,0.891,0.923,0.961,1.102,1.032,1.065,1.153,7.92E-3,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0046907 intracellular transport; GO:0072594 establishment of protein localization to organelle; GO:0017038 protein import; GO:1902593 single-organism nuclear import; GO:0044699 single-organism process; GO:0051169 nuclear transport; GO:0044764 multi-organism cellular process; GO:0050896 response to stimulus; GO:0015031 protein transport; GO:0045087 innate immune response; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:1902578 single-organism localization; GO:0007154 cell communication; GO:0016032 viral process; GO:0006886 intracellular protein transport; GO:0044744 protein targeting to nucleus; GO:1902580 single-organism cellular localization; GO:0033365 protein localization to organelle; GO:0006606 protein import into nucleus; GO:0034613 cellular protein localization; GO:0044419 interspecies interaction between organisms; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0009987 cellular process; GO:0044765 single-organism transport; GO:0051716 cellular response to stimulus; GO:0006950 response to stress; GO:0002376 immune system process; GO:0071702 organic substance transport; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0023052 signaling; GO:1902582 single-organism intracellular transport; GO:0051704 multi-organism process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:0070727 cellular macromolecule localization; GO:0050789 regulation of biological process; GO:0051170 nuclear import; GO:0050790 regulation of catalytic activity; GO:0065009 regulation of molecular function; GO:0006913 nucleocytoplasmic transport; GO:0006952 defense response; GO:0051179 localization; GO:0006955 immune response; GO:0034504 protein localization to nucleus; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005643 nuclear pore; GO:0005635 nuclear envelope; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0031975 envelope; GO:0043227 membrane-bounded organelle; GO:0043234 protein complex; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0031267 small GTPase binding; GO:0042393 histone binding; GO:0030234 enzyme regulator activity; GO:0017016 Ras GTPase binding; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0005488 binding; GO:0030695 GTPase regulator activity; GO:0008536 Ran GTPase binding; GO:0005515 protein binding; GO:0051020 GTPase binding; GO:0098772 molecular function regulator; GO:0046332 SMAD binding; GO:0019899 enzyme binding; GO:0005215 transporter activity; ","K20223",null,null,"IPR001494; IPR011989; IPR016024; IPR013713; ","\"Importin-beta, N-terminal domain; Armadillo-like helical; Armadillo-type fold; Exportin/Importin, Cse1-like; \"\r"]
["O95379","Tumor necrosis factor alpha-induced protein 8 OS=Homo sapiens OX=9606 GN=TNFAIP8","TNFAIP8",23.003,2.8244,4.5,1,1,1,0.988,1.139,0.945,0.891,0.911,1.137,0.957,0.649,"cytoplasm\r","GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0050794 regulation of cellular process; GO:0010941 regulation of cell death; GO:0010951 negative regulation of endopeptidase activity; GO:0043069 negative regulation of programmed cell death; GO:0060255 regulation of macromolecule metabolic process; GO:0043067 regulation of programmed cell death; GO:0044699 single-organism process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0051346 negative regulation of hydrolase activity; GO:0010466 negative regulation of peptidase activity; GO:0043066 negative regulation of apoptotic process; GO:0006915 apoptotic process; GO:2000117 negative regulation of cysteine-type endopeptidase activity; GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0009987 cellular process; GO:0052548 regulation of endopeptidase activity; GO:0045861 negative regulation of proteolysis; GO:2000116 regulation of cysteine-type endopeptidase activity; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0030162 regulation of proteolysis; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0009892 negative regulation of metabolic process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:0008219 cell death; GO:0051246 regulation of protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0065009 regulation of molecular function; GO:0051248 negative regulation of protein metabolic process; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0012501 programmed cell death; GO:0052547 regulation of peptidase activity; GO:0060548 negative regulation of cell death; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0044424 intracellular part; GO:0005623 cell; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; ","GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0030414 peptidase inhibitor activity; GO:0061134 peptidase regulator activity; GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process; GO:0005515 protein binding; GO:0061135 endopeptidase regulator activity; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0004866 endopeptidase inhibitor activity; GO:0004869 cysteine-type endopeptidase inhibitor activity; "]
["O95394","Phosphoacetylglucosamine mutase OS=Homo sapiens OX=9606 GN=PGM3","PGM3",59.851,19.201,13.8,7,9,7,1.037,1.138,0.973,0.991,0.915,1.008,0.926,0.235,"cytoplasm\r","GO:0009226 nucleotide-sugar biosynthetic process; GO:0043413 macromolecule glycosylation; GO:0022414 reproductive process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0044702 single organism reproductive process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006487 protein N-linked glycosylation; GO:0032502 developmental process; GO:0006047 UDP-N-acetylglucosamine metabolic process; GO:0006486 protein glycosylation; GO:0018130 heterocycle biosynthetic process; GO:0009101 glycoprotein biosynthetic process; GO:0019953 sexual reproduction; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0009100 glycoprotein metabolic process; GO:0002520 immune system development; GO:0006048 UDP-N-acetylglucosamine biosynthetic process; GO:0005975 carbohydrate metabolic process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0048513 animal organ development; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0006493 protein O-linked glycosylation; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0048609 multicellular organismal reproductive process; GO:1901362 organic cyclic compound biosynthetic process; GO:0000003 reproduction; GO:0044707 single-multicellular organism process; GO:1901071 glucosamine-containing compound metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0019255 glucose 1-phosphate metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0070085 glycosylation; GO:0048232 male gamete generation; GO:0048731 system development; GO:0007283 spermatogenesis; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0048534 hematopoietic or lymphoid organ development; GO:0030097 hemopoiesis; GO:0007276 gamete generation; GO:0044249 cellular biosynthetic process; GO:0006041 glucosamine metabolic process; GO:0032504 multicellular organism reproduction; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0044767 single-organism developmental process; GO:0044703 multi-organism reproductive process; GO:0019637 organophosphate metabolic process; GO:0006040 amino sugar metabolic process; GO:0009225 nucleotide-sugar metabolic process; GO:0043412 macromolecule modification; GO:0046349 amino sugar biosynthetic process; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:0000287 magnesium ion binding; GO:0016853 isomerase activity; GO:0004610 phosphoacetylglucosamine mutase activity; GO:0003824 catalytic activity; GO:0004614 phosphoglucomutase activity; GO:0005488 binding; GO:0016868 intramolecular transferase activity, phosphotransferases; GO:0043167 ion binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0016866 intramolecular transferase activity; ","K01836","PGM3; phosphoacetylglucosamine mutase [EC:5.4.2.3]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00520 Amino sugar and nucleotide sugar metabolism - Homo sapiens (human); ","IPR005843; IPR016055; IPR005844; ","\"Alpha-D-phosphohexomutase, C-terminal; Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III; Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; \"\r"]
["O95425","Supervillin OS=Homo sapiens OX=9606 GN=SVIL","SVIL",247.74,69.304,5.9,10,10,10,1.054,1.092,0.989,0.968,0.939,0.975,0.919,0.0555,"nucleus\r","GO:0014706 striated muscle tissue development; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0044699 single-organism process; GO:0032465 regulation of cytokinesis; GO:0010564 regulation of cell cycle process; GO:0032467 positive regulation of cytokinesis; GO:0061061 muscle structure development; GO:0007275 multicellular organism development; GO:0090068 positive regulation of cell cycle process; GO:0007010 cytoskeleton organization; GO:0007519 skeletal muscle tissue development; GO:0009987 cellular process; GO:0051726 regulation of cell cycle; GO:0045787 positive regulation of cell cycle; GO:0032502 developmental process; GO:0009888 tissue development; GO:0051781 positive regulation of cell division; GO:0048731 system development; GO:0060537 muscle tissue development; GO:0048522 positive regulation of cellular process; GO:0048518 positive regulation of biological process; GO:0032501 multicellular organismal process; GO:0060538 skeletal muscle organ development; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0051302 regulation of cell division; GO:0007517 muscle organ development; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0048856 anatomical structure development; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0036449 microtubule minus-end; GO:0005874 microtubule; GO:0071437 invadopodium; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0030016 myofibril; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:1990752 microtubule end; GO:0044424 intracellular part; GO:0099512 supramolecular fiber; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0032155 cell division site part; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0005925 focal adhesion; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0043292 contractile fiber; GO:0005912 adherens junction; GO:0030055 cell-substrate junction; GO:0032154 cleavage furrow; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0099513 polymeric cytoskeletal fiber; GO:0097610 cell surface furrow; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0032153 cell division site; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0030496 midbody; GO:0002102 podosome; GO:0005829 cytosol; GO:0015629 actin cytoskeleton; GO:0005886 plasma membrane; GO:0099081 supramolecular polymer; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0043034 costamere; GO:0044449 contractile fiber part; GO:0009986 cell surface; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0051015 actin filament binding; GO:0008092 cytoskeletal protein binding; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0003779 actin binding; GO:0005515 protein binding; GO:0032403 protein complex binding; ","K10369",null,null,"IPR003128; IPR029006; IPR007123; ","Villin headpiece; ADF-H/Gelsolin-like domain; Gelsolin-like domain; \r"]
["O95433","Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Homo sapiens OX=9606 GN=AHSA1","AHSA1",38.274,86.087,31.1,8,10,8,0.905,0.965,0.973,1.081,1.028,1.043,1.109,0.0194,"cytoplasm\r","GO:0006950 response to stress; GO:0051336 regulation of hydrolase activity; GO:0043462 regulation of ATPase activity; GO:0051345 positive regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0044093 positive regulation of molecular function; GO:0065009 regulation of molecular function; GO:0032781 positive regulation of ATPase activity; GO:0050896 response to stimulus; GO:0065007 biological regulation; GO:0043085 positive regulation of catalytic activity; ","GO:0043229 intracellular organelle; GO:0005783 endoplasmic reticulum; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0050839 cell adhesion molecule binding; GO:0001671 ATPase activator activity; GO:0030234 enzyme regulator activity; GO:0051087 chaperone binding; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0005488 binding; GO:0045296 cadherin binding; GO:0005515 protein binding; GO:0060590 ATPase regulator activity; GO:0098772 molecular function regulator; GO:0008047 enzyme activator activity; ",{"$nulls":3},"IPR015310; IPR023393; ","\"Activator of Hsp90 ATPase, N-terminal; START-like domain; \"\r"]
["O95445","Apolipoprotein M OS=Homo sapiens OX=9606 GN=APOM","APOM",21.253,7.1775,14.4,3,3,3,0.975,0.907,1.033,1.079,1.033,0.977,1.06,0.284,"extracellular\r","GO:0034367 macromolecular complex remodeling; GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0015850 organic hydroxy compound transport; GO:0009746 response to hexose; GO:0033344 cholesterol efflux; GO:0030301 cholesterol transport; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0034442 regulation of lipoprotein oxidation; GO:0009749 response to glucose; GO:0044237 cellular metabolic process; GO:0042157 lipoprotein metabolic process; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0071825 protein-lipid complex subunit organization; GO:0098869 cellular oxidant detoxification; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009743 response to carbohydrate; GO:0033036 macromolecule localization; GO:0043691 reverse cholesterol transport; GO:0055088 lipid homeostasis; GO:0006629 lipid metabolic process; GO:0044765 single-organism transport; GO:0071827 plasma lipoprotein particle organization; GO:0006869 lipid transport; GO:0080090 regulation of primary metabolic process; GO:0009636 response to toxic substance; GO:0044763 single-organism cellular process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0006810 transport; GO:0034443 negative regulation of lipoprotein oxidation; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0034377 plasma lipoprotein particle assembly; GO:0034384 high-density lipoprotein particle clearance; GO:0044710 single-organism metabolic process; GO:0034284 response to monosaccharide; GO:0019222 regulation of metabolic process; GO:0016101 diterpenoid metabolic process; GO:0065005 protein-lipid complex assembly; GO:0034444 regulation of plasma lipoprotein particle oxidation; GO:0098754 detoxification; GO:0015918 sterol transport; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0060255 regulation of macromolecule metabolic process; GO:1901700 response to oxygen-containing compound; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0034445 negative regulation of plasma lipoprotein particle oxidation; GO:0097006 regulation of plasma lipoprotein particle levels; GO:0042592 homeostatic process; GO:1990748 cellular detoxification; GO:1902578 single-organism localization; GO:0034369 plasma lipoprotein particle remodeling; GO:0001523 retinoid metabolic process; GO:0050748 negative regulation of lipoprotein metabolic process; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0050746 regulation of lipoprotein metabolic process; GO:0006720 isoprenoid metabolic process; GO:0010876 lipid localization; GO:0071702 organic substance transport; GO:0010033 response to organic substance; GO:0034381 plasma lipoprotein particle clearance; GO:0042632 cholesterol homeostasis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0051246 regulation of protein metabolic process; GO:0034380 high-density lipoprotein particle assembly; GO:0055092 sterol homeostasis; GO:0051248 negative regulation of protein metabolic process; GO:0006721 terpenoid metabolic process; GO:0034375 high-density lipoprotein particle remodeling; GO:0034368 protein-lipid complex remodeling; GO:0051179 localization; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0031226 intrinsic component of plasma membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0034362 low-density lipoprotein particle; GO:0031982 vesicle; GO:0034358 plasma lipoprotein particle; GO:0034385 triglyceride-rich plasma lipoprotein particle; GO:0031224 intrinsic component of membrane; GO:0032991 macromolecular complex; GO:0005887 integral component of plasma membrane; GO:0034364 high-density lipoprotein particle; GO:0005623 cell; GO:0034361 very-low-density lipoprotein particle; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0034365 discoidal high-density lipoprotein particle; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0032994 protein-lipid complex; GO:0044464 cell part; GO:0044425 membrane part; GO:0034366 spherical high-density lipoprotein particle; GO:1990777 lipoprotein particle; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0005488 binding; GO:0005543 phospholipid binding; GO:0043167 ion binding; GO:0016209 antioxidant activity; GO:0005319 lipid transporter activity; GO:0008289 lipid binding; GO:0022892 substrate-specific transporter activity; GO:0043168 anion binding; GO:0005215 transporter activity; ",{"$nulls":3},"IPR011038; ","Calycin-like; \r"]
["O95460","Matrilin-4 OS=Homo sapiens OX=9606 GN=MATN4","MATN4",68.486,9.4482,5.5,3,4,3,1.211,1.199,1.22,0.744,0.86,0.798,0.662,0.0102,"extracellular\r","GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0016043 cellular component organization; GO:0030198 extracellular matrix organization; GO:0009987 cellular process; GO:0043062 extracellular structure organization; GO:0071840 cellular component organization or biogenesis; ","GO:0005576 extracellular region; ","GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0005509 calcium ion binding; GO:0005488 binding; GO:0043167 ion binding; ",{"$nulls":3},"IPR026823; IPR019466; IPR001881; IPR000742; IPR009030; IPR002035; ","\"Complement Clr-like EGF domain; Matrilin, coiled-coil trimerisation domain; EGF-like calcium-binding domain; EGF-like domain; Growth factor receptor cysteine-rich domain; von Willebrand factor, type A; \"\r"]
["O95466","Formin-like protein 1 OS=Homo sapiens OX=9606 GN=FMNL1","FMNL1",121.85,30.132,6,5,5,5,0.986,0.992,0.974,1.017,0.986,1.052,1.035,0.156,"nucleus\r","GO:0050794 regulation of cellular process; GO:0016477 cell migration; GO:0016043 cellular component organization; GO:0065008 regulation of biological quality; GO:0051674 localization of cell; GO:0030866 cortical actin cytoskeleton organization; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0048870 cell motility; GO:0030865 cortical cytoskeleton organization; GO:1902589 single-organism organelle organization; GO:0030036 actin cytoskeleton organization; GO:0050789 regulation of biological process; GO:0006996 organelle organization; GO:0008360 regulation of cell shape; GO:0022603 regulation of anatomical structure morphogenesis; GO:0030029 actin filament-based process; GO:0006928 movement of cell or subcellular component; GO:0040011 locomotion; GO:0051128 regulation of cellular component organization; GO:0006929 substrate-dependent cell migration; GO:0051179 localization; GO:0007010 cytoskeleton organization; GO:0022604 regulation of cell morphogenesis; GO:0050793 regulation of developmental process; GO:0009987 cellular process; GO:0051014 actin filament severing; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0042995 cell projection; GO:0005938 cell cortex; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0099568 cytoplasmic region; GO:0045335 phagocytic vesicle; GO:0044424 intracellular part; GO:0032059 bleb; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0030139 endocytic vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0031267 small GTPase binding; GO:0051015 actin filament binding; GO:0017048 Rho GTPase binding; GO:0048365 Rac GTPase binding; GO:0008092 cytoskeletal protein binding; GO:0017016 Ras GTPase binding; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0003779 actin binding; GO:0005522 profilin binding; GO:0005515 protein binding; GO:0051020 GTPase binding; GO:0019899 enzyme binding; GO:0032794 GTPase activating protein binding; GO:0032403 protein complex binding; ",{"$nulls":3},"IPR010473; IPR014767; IPR010472; IPR014768; IPR015425; IPR016024; ","\"Formin, GTPase-binding domain; Diaphanous autoregulatory (DAD) domain; Formin, FH3 domain; Rho GTPase-binding/formin homology 3 (GBD/FH3) domain; Formin, FH2 domain; Armadillo-type fold; \"\r"]
["O95479","GDH/6PGL endoplasmic bifunctional protein OS=Homo sapiens OX=9606 GN=H6PD","H6PD",88.892,63.749,16.9,10,17,10,1.003,1.079,1.069,0.917,0.96,0.924,0.889,0.0121,"extracellular\r","GO:0006739 NADP metabolic process; GO:0019362 pyridine nucleotide metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0046496 nicotinamide nucleotide metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0072524 pyridine-containing compound metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0006006 glucose metabolic process; GO:0051156 glucose 6-phosphate metabolic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019682 glyceraldehyde-3-phosphate metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0005996 monosaccharide metabolic process; GO:0006098 pentose-phosphate shunt; GO:1901135 carbohydrate derivative metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006081 cellular aldehyde metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0006732 coenzyme metabolic process; GO:0005975 carbohydrate metabolic process; GO:0044238 primary metabolic process; GO:0051186 cofactor metabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0019637 organophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0019318 hexose metabolic process; ","GO:0005788 endoplasmic reticulum lumen; GO:0043229 intracellular organelle; GO:0005783 endoplasmic reticulum; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044432 endoplasmic reticulum part; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0017057 6-phosphogluconolactonase activity; GO:1901265 nucleoside phosphate binding; GO:0052689 carboxylic ester hydrolase activity; GO:0016787 hydrolase activity; GO:0000166 nucleotide binding; GO:0048037 cofactor binding; GO:0016491 oxidoreductase activity; GO:0016614 oxidoreductase activity, acting on CH-OH group of donors; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0004345 glucose-6-phosphate dehydrogenase activity; GO:0050661 NADP binding; GO:0047936 glucose 1-dehydrogenase [NAD(P)] activity; GO:0036094 small molecule binding; GO:0050662 coenzyme binding; ","K13937","H6PD; hexose-6-phosphate dehydrogenase [EC:1.1.1.47 3.1.1.31]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00030 Pentose phosphate pathway - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); ","IPR022675; IPR006148; IPR016040; IPR005900; IPR022674; ","\"Glucose-6-phosphate dehydrogenase, C-terminal; Glucosamine/galactosamine-6-phosphate isomerase; NAD(P)-binding domain; 6-phosphogluconolactonase, DevB-type; Glucose-6-phosphate dehydrogenase, NAD-binding; \"\r"]
["O95487","Protein transport protein Sec24B OS=Homo sapiens OX=9606 GN=SEC24B","SEC24B",137.42,3.3554,0.8,1,1,1,0.978,0.993,0.972,1.037,1.028,0.999,1.041,0.036,"nucleus\r","GO:0060627 regulation of vesicle-mediated transport; GO:0044085 cellular component biogenesis; GO:0048208 COPII vesicle coating; GO:0035148 tube formation; GO:0043009 chordate embryonic development; GO:0007420 brain development; GO:0060463 lung lobe morphogenesis; GO:0030323 respiratory tube development; GO:0032989 cellular component morphogenesis; GO:0015031 protein transport; GO:0035315 hair cell differentiation; GO:0048857 neural nucleus development; GO:0009913 epidermal cell differentiation; GO:0060462 lung lobe development; GO:0007507 heart development; GO:0048562 embryonic organ morphogenesis; GO:0032879 regulation of localization; GO:0003151 outflow tract morphogenesis; GO:0065003 macromolecular complex assembly; GO:0048199 vesicle targeting, to, from or within Golgi; GO:0008544 epidermis development; GO:0009790 embryo development; GO:0008104 protein localization; GO:0090596 sensory organ morphogenesis; GO:0048598 embryonic morphogenesis; GO:0007399 nervous system development; GO:0002064 epithelial cell development; GO:0048699 generation of neurons; GO:0035239 tube morphogenesis; GO:0044763 single-organism cellular process; GO:0032501 multicellular organismal process; GO:0060976 coronary vasculature development; GO:0000902 cell morphogenesis; GO:0006810 transport; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0060982 coronary artery morphogenesis; GO:0048513 animal organ development; GO:0043583 ear development; GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; GO:0007417 central nervous system development; GO:0009887 animal organ morphogenesis; GO:0048844 artery morphogenesis; GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II; GO:0030855 epithelial cell differentiation; GO:0050794 regulation of cellular process; GO:0072359 circulatory system development; GO:0051640 organelle localization; GO:0002009 morphogenesis of an epithelium; GO:0044707 single-multicellular organism process; GO:0046907 intracellular transport; GO:0060977 coronary vasculature morphogenesis; GO:0051239 regulation of multicellular organismal process; GO:0060341 regulation of cellular localization; GO:0009653 anatomical structure morphogenesis; GO:0060606 tube closure; GO:0021747 cochlear nucleus development; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0060541 respiratory system development; GO:1901301 regulation of cargo loading into COPII-coated vesicle; GO:0042491 auditory receptor cell differentiation; GO:0016331 morphogenesis of embryonic epithelium; GO:0007275 multicellular organism development; GO:0034613 cellular protein localization; GO:0001843 neural tube closure; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0006461 protein complex assembly; GO:0030902 hindbrain development; GO:0060088 auditory receptor cell stereocilium organization; GO:0060562 epithelial tube morphogenesis; GO:0090114 COPII-coated vesicle budding; GO:0048731 system development; GO:0051960 regulation of nervous system development; GO:0035909 aorta morphogenesis; GO:0016192 vesicle-mediated transport; GO:0072358 cardiovascular system development; GO:0002376 immune system process; GO:0071702 organic substance transport; GO:0048839 inner ear development; GO:0051656 establishment of organelle localization; GO:0060117 auditory receptor cell development; GO:0045184 establishment of protein localization; GO:0030182 neuron differentiation; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0006900 membrane budding; GO:0007423 sensory organ development; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0001841 neural tube formation; GO:0006901 vesicle coating; GO:0048207 vesicle targeting, rough ER to cis-Golgi; GO:0060113 inner ear receptor cell differentiation; GO:0001568 blood vessel development; GO:0048869 cellular developmental process; GO:0048666 neuron development; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0042472 inner ear morphogenesis; GO:0051234 establishment of localization; GO:1905330 regulation of morphogenesis of an epithelium; GO:0048729 tissue morphogenesis; GO:0051649 establishment of localization in cell; GO:0022607 cellular component assembly; GO:0060628 regulation of ER to Golgi vesicle-mediated transport; GO:0060322 head development; GO:1905276 regulation of epithelial tube formation; GO:0048514 blood vessel morphogenesis; GO:0033036 macromolecule localization; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0032502 developmental process; GO:0030324 lung development; GO:0035295 tube development; GO:0051650 establishment of vesicle localization; GO:0060429 epithelium development; GO:0071822 protein complex subunit organization; GO:0009888 tissue development; GO:0048002 antigen processing and presentation of peptide antigen; GO:0003007 heart morphogenesis; GO:0001944 vasculature development; GO:0032386 regulation of intracellular transport; GO:0002495 antigen processing and presentation of peptide antigen via MHC class II; GO:0035904 aorta development; GO:0050789 regulation of biological process; GO:0030030 cell projection organization; GO:0060840 artery development; GO:0002065 columnar/cuboidal epithelial cell differentiation; GO:0060122 inner ear receptor stereocilium organization; GO:0022037 metencephalon development; GO:0070271 protein complex biogenesis; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0090175 regulation of establishment of planar polarity; GO:0016043 cellular component organization; GO:0060425 lung morphogenesis; GO:0048568 embryonic organ development; GO:0048193 Golgi vesicle transport; GO:0044087 regulation of cellular component biogenesis; GO:0006903 vesicle targeting; GO:0021548 pons development; GO:0021915 neural tube development; GO:0048468 cell development; GO:0000904 cell morphogenesis involved in differentiation; GO:0072175 epithelial tube formation; GO:0030154 cell differentiation; GO:2000027 regulation of organ morphogenesis; GO:0051648 vesicle localization; GO:0006886 intracellular protein transport; GO:0009987 cellular process; GO:0051049 regulation of transport; GO:0061156 pulmonary artery morphogenesis; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:0009792 embryo development ending in birth or egg hatching; GO:0042490 mechanoreceptor differentiation; GO:0016050 vesicle organization; GO:0033043 regulation of organelle organization; GO:0002066 columnar/cuboidal epithelial cell development; GO:0002093 auditory receptor cell morphogenesis; GO:0051641 cellular localization; GO:0043933 macromolecular complex subunit organization; GO:0001838 embryonic epithelial tube formation; GO:0014020 primary neural tube formation; GO:0019882 antigen processing and presentation; GO:0070727 cellular macromolecule localization; GO:0045995 regulation of embryonic development; GO:0044767 single-organism developmental process; GO:0090178 regulation of establishment of planar polarity involved in neural tube closure; GO:0022603 regulation of anatomical structure morphogenesis; GO:0042471 ear morphogenesis; GO:0060119 inner ear receptor cell development; GO:0051128 regulation of cellular component organization; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0060563 neuroepithelial cell differentiation; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0030658 transport vesicle membrane; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0030120 vesicle coat; GO:0005623 cell; GO:0030662 coated vesicle membrane; GO:0044422 organelle part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0044431 Golgi apparatus part; GO:0048471 perinuclear region of cytoplasm; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0012507 ER to Golgi transport vesicle membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0048475 coated membrane; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0030134 ER to Golgi transport vesicle; GO:0012506 vesicle membrane; GO:0005829 cytosol; GO:0030135 coated vesicle; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044432 endoplasmic reticulum part; GO:0030117 membrane coat; GO:0030127 COPII vesicle coat; GO:0043234 protein complex; GO:0005794 Golgi apparatus; GO:0030133 transport vesicle; GO:0044444 cytoplasmic part; ","GO:0046914 transition metal ion binding; GO:0005488 binding; GO:0043167 ion binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0008270 zinc ion binding; GO:0005215 transporter activity; ","K14007","SEC24; protein transport protein SEC24","hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); ","IPR006900; IPR012990; IPR006896; IPR029006; IPR006895; IPR007123; IPR002035; ","\"Sec23/Sec24, helical domain; Sec23/Sec24 beta-sandwich; Sec23/Sec24, trunk domain; ADF-H/Gelsolin-like domain; Zinc finger, Sec23/Sec24-type; Gelsolin-like domain; von Willebrand factor, type A; \"\r"]
["O95563","Mitochondrial pyruvate carrier 2 OS=Homo sapiens OX=9606 GN=MPC2","MPC2",14.279,6.6857,14.2,2,5,2,1.028,0.965,1.09,0.983,1.028,0.943,0.958,0.384,"mitochondria\r","GO:0051188 cofactor biosynthetic process; GO:0065008 regulation of biological quality; GO:0019362 pyridine nucleotide metabolic process; GO:0009117 nucleotide metabolic process; GO:0006839 mitochondrial transport; GO:0050796 regulation of insulin secretion; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0051046 regulation of secretion; GO:0009058 biosynthetic process; GO:0002793 positive regulation of peptide secretion; GO:0044237 cellular metabolic process; GO:0072524 pyridine-containing compound metabolic process; GO:0035384 thioester biosynthetic process; GO:0044272 sulfur compound biosynthetic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0006085 acetyl-CoA biosynthetic process; GO:0008152 metabolic process; GO:0010646 regulation of cell communication; GO:0015718 monocarboxylic acid transport; GO:0006753 nucleoside phosphate metabolic process; GO:0032879 regulation of localization; GO:0032846 positive regulation of homeostatic process; GO:0032787 monocarboxylic acid metabolic process; GO:0009108 coenzyme biosynthetic process; GO:1905039 carboxylic acid transmembrane transport; GO:0044765 single-organism transport; GO:0006790 sulfur compound metabolic process; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0071616 acyl-CoA biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0006732 coenzyme metabolic process; GO:0006084 acetyl-CoA metabolic process; GO:0046942 carboxylic acid transport; GO:1903530 regulation of secretion by cell; GO:1902361 mitochondrial pyruvate transmembrane transport; GO:0051186 cofactor metabolic process; GO:0051050 positive regulation of transport; GO:0006810 transport; GO:0046883 regulation of hormone secretion; GO:0050789 regulation of biological process; GO:1903532 positive regulation of secretion by cell; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:0050714 positive regulation of protein secretion; GO:0010817 regulation of hormone levels; GO:0051223 regulation of protein transport; GO:0006082 organic acid metabolic process; GO:0043436 oxoacid metabolic process; GO:0051222 positive regulation of protein transport; GO:0051047 positive regulation of secretion; GO:0050794 regulation of cellular process; GO:0034220 ion transmembrane transport; GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus; GO:0006725 cellular aromatic compound metabolic process; GO:0046496 nicotinamide nucleotide metabolic process; GO:0032844 regulation of homeostatic process; GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate; GO:0098656 anion transmembrane transport; GO:0090277 positive regulation of peptide hormone secretion; GO:0070201 regulation of establishment of protein localization; GO:0071704 organic substance metabolic process; GO:0060341 regulation of cellular localization; GO:0006090 pyruvate metabolic process; GO:0002791 regulation of peptide secretion; GO:0046483 heterocycle metabolic process; GO:1902578 single-organism localization; GO:1903825 organic acid transmembrane transport; GO:0006139 nucleobase-containing compound metabolic process; GO:0023056 positive regulation of signaling; GO:1990542 mitochondrial transmembrane transport; GO:0006850 mitochondrial pyruvate transport; GO:0034641 cellular nitrogen compound metabolic process; GO:0010647 positive regulation of cell communication; GO:0032880 regulation of protein localization; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0050708 regulation of protein secretion; GO:0009987 cellular process; GO:0090087 regulation of peptide transport; GO:0032024 positive regulation of insulin secretion; GO:0044711 single-organism biosynthetic process; GO:0051049 regulation of transport; GO:0035383 thioester metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0048518 positive regulation of biological process; GO:0015849 organic acid transport; GO:0044249 cellular biosynthetic process; GO:0006637 acyl-CoA metabolic process; GO:0006820 anion transport; GO:0055085 transmembrane transport; GO:0015711 organic anion transport; GO:1904951 positive regulation of establishment of protein localization; GO:0006793 phosphorus metabolic process; GO:0006811 ion transport; GO:0019752 carboxylic acid metabolic process; GO:0046887 positive regulation of hormone secretion; GO:0090276 regulation of peptide hormone secretion; GO:1901475 pyruvate transmembrane transport; GO:0019637 organophosphate metabolic process; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:0006848 pyruvate transport; GO:0006086 acetyl-CoA biosynthetic process from pyruvate; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0031305 integral component of mitochondrial inner membrane; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0031304 intrinsic component of mitochondrial inner membrane; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0031301 integral component of organelle membrane; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0043229 intracellular organelle; GO:0098573 intrinsic component of mitochondrial membrane; GO:0044429 mitochondrial part; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0016021 integral component of membrane; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0031975 envelope; GO:0032592 integral component of mitochondrial membrane; GO:0031966 mitochondrial membrane; GO:0031300 intrinsic component of organelle membrane; GO:0044444 cytoplasmic part; ","GO:0005342 organic acid transmembrane transporter activity; GO:0015075 ion transmembrane transporter activity; GO:0050833 pyruvate transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0008028 monocarboxylic acid transmembrane transporter activity; GO:0008514 organic anion transmembrane transporter activity; GO:0046943 carboxylic acid transmembrane transporter activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0022857 transmembrane transporter activity; GO:0008509 anion transmembrane transporter activity; GO:0005215 transporter activity; "]
["O95571","Persulfide dioxygenase ETHE1, mitochondrial OS=Homo sapiens OX=9606 GN=ETHE1","ETHE1",27.873,27.04,24.4,5,9,5,0.962,1.005,0.993,1.063,0.965,1.001,1.023,0.511,"mitochondria\r","GO:0006790 sulfur compound metabolic process; GO:0006518 peptide metabolic process; GO:0070221 sulfide oxidation, using sulfide:quinone oxidoreductase; GO:0055114 oxidation-reduction process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:0044699 single-organism process; GO:0043603 cellular amide metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0019418 sulfide oxidation; GO:0006575 cellular modified amino acid metabolic process; GO:0044710 single-organism metabolic process; GO:0006749 glutathione metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009987 cellular process; GO:0070813 hydrogen sulfide metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen; GO:0005506 iron ion binding; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0051213 dioxygenase activity; GO:0005488 binding; GO:0043167 ion binding; GO:0050313 sulfur dioxygenase activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0016491 oxidoreductase activity; ","K17725","ETHE1; sulfur dioxygenase [EC:1.13.11.18]","hsa00920 Sulfur metabolism - Homo sapiens (human); ","IPR001279; ","Metallo-beta-lactamase; \r"]
["O95573","Long-chain-fatty-acid--CoA ligase 3 OS=Homo sapiens OX=9606 GN=ACSL3","ACSL3",80.419,18.305,6.9,3,4,2,1.055,0.976,1.011,0.961,1.037,0.97,0.976,0.494,"extracellular\r","GO:0060627 regulation of vesicle-mediated transport; GO:0044085 cellular component biogenesis; GO:0007420 brain development; GO:0035337 fatty-acyl-CoA metabolic process; GO:0009891 positive regulation of biosynthetic process; GO:0034379 very-low-density lipoprotein particle assembly; GO:0044255 cellular lipid metabolic process; GO:0019216 regulation of lipid metabolic process; GO:0044237 cellular metabolic process; GO:0044272 sulfur compound biosynthetic process; GO:0008610 lipid biosynthetic process; GO:0009605 response to external stimulus; GO:1903729 regulation of plasma membrane organization; GO:0008152 metabolic process; GO:0015718 monocarboxylic acid transport; GO:0032879 regulation of localization; GO:0065003 macromolecular complex assembly; GO:0071825 protein-lipid complex subunit organization; GO:0032787 monocarboxylic acid metabolic process; GO:0009108 coenzyme biosynthetic process; GO:0010562 positive regulation of phosphorus metabolic process; GO:0044765 single-organism transport; GO:0046889 positive regulation of lipid biosynthetic process; GO:0006790 sulfur compound metabolic process; GO:0007399 nervous system development; GO:0014070 response to organic cyclic compound; GO:0051174 regulation of phosphorus metabolic process; GO:0006869 lipid transport; GO:0042998 positive regulation of Golgi to plasma membrane protein transport; GO:0080090 regulation of primary metabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006732 coenzyme metabolic process; GO:0046942 carboxylic acid transport; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:0048513 animal organ development; GO:0034377 plasma lipoprotein particle assembly; GO:0044710 single-organism metabolic process; GO:0007417 central nervous system development; GO:0046890 regulation of lipid biosynthetic process; GO:0051223 regulation of protein transport; GO:0042996 regulation of Golgi to plasma membrane protein transport; GO:0043436 oxoacid metabolic process; GO:0051047 positive regulation of secretion; GO:2001245 regulation of phosphatidylcholine biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:1903076 regulation of protein localization to plasma membrane; GO:1903725 regulation of phospholipid metabolic process; GO:1903078 positive regulation of protein localization to plasma membrane; GO:1905477 positive regulation of protein localization to membrane; GO:0060341 regulation of cellular localization; GO:1902578 single-organism localization; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0032880 regulation of protein localization; GO:0007275 multicellular organism development; GO:0090003 regulation of establishment of protein localization to plasma membrane; GO:1904377 positive regulation of protein localization to cell periphery; GO:0044711 single-organism biosynthetic process; GO:0048731 system development; GO:0035383 thioester metabolic process; GO:0071702 organic substance transport; GO:0010876 lipid localization; GO:0010033 response to organic substance; GO:0007584 response to nutrient; GO:0044238 primary metabolic process; GO:0015849 organic acid transport; GO:1901576 organic substance biosynthetic process; GO:0015909 long-chain fatty acid transport; GO:1904951 positive regulation of establishment of protein localization; GO:0006793 phosphorus metabolic process; GO:0001676 long-chain fatty acid metabolic process; GO:0006811 ion transport; GO:0071073 positive regulation of phospholipid biosynthetic process; GO:0031325 positive regulation of cellular metabolic process; GO:0044283 small molecule biosynthetic process; GO:0051179 localization; GO:1903727 positive regulation of phospholipid metabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0072330 monocarboxylic acid biosynthetic process; GO:1903827 regulation of cellular protein localization; GO:0051188 cofactor biosynthetic process; GO:0016053 organic acid biosynthetic process; GO:0051046 regulation of secretion; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0035384 thioester biosynthetic process; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:1904375 regulation of protein localization to cell periphery; GO:0022607 cellular component assembly; GO:0071071 regulation of phospholipid biosynthetic process; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0060322 head development; GO:0033036 macromolecule localization; GO:0006629 lipid metabolic process; GO:0071827 plasma lipoprotein particle organization; GO:0032502 developmental process; GO:0045937 positive regulation of phosphate metabolic process; GO:0031326 regulation of cellular biosynthetic process; GO:0071616 acyl-CoA biosynthetic process; GO:0048522 positive regulation of cellular process; GO:0035336 long-chain fatty-acyl-CoA metabolic process; GO:0006633 fatty acid biosynthetic process; GO:0035338 long-chain fatty-acyl-CoA biosynthetic process; GO:0051050 positive regulation of transport; GO:0051186 cofactor metabolic process; GO:0046394 carboxylic acid biosynthetic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0019222 regulation of metabolic process; GO:0065005 protein-lipid complex assembly; GO:0019220 regulation of phosphate metabolic process; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:0051222 positive regulation of protein transport; GO:0016043 cellular component organization; GO:0046949 fatty-acyl-CoA biosynthetic process; GO:1903829 positive regulation of cellular protein localization; GO:0050896 response to stimulus; GO:0070201 regulation of establishment of protein localization; GO:0071704 organic substance metabolic process; GO:0097006 regulation of plasma lipoprotein particle levels; GO:0090004 positive regulation of establishment of protein localization to plasma membrane; GO:0009991 response to extracellular stimulus; GO:0015908 fatty acid transport; GO:1905475 regulation of protein localization to membrane; GO:2001247 positive regulation of phosphatidylcholine biosynthetic process; GO:0009987 cellular process; GO:0051049 regulation of transport; GO:0006631 fatty acid metabolic process; GO:0048518 positive regulation of biological process; GO:0045834 positive regulation of lipid metabolic process; GO:0044249 cellular biosynthetic process; GO:0006637 acyl-CoA metabolic process; GO:0044539 long-chain fatty acid import; GO:0043933 macromolecular complex subunit organization; GO:0006820 anion transport; GO:0015711 organic anion transport; GO:0044767 single-organism developmental process; GO:0019752 carboxylic acid metabolic process; GO:0051128 regulation of cellular component organization; GO:0031667 response to nutrient levels; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0019867 outer membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044438 microbody part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005778 peroxisomal membrane; GO:0005740 mitochondrial envelope; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0042579 microbody; GO:0098805 whole membrane; GO:0048471 perinuclear region of cytoplasm; GO:0031968 organelle outer membrane; GO:0005811 lipid particle; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043229 intracellular organelle; GO:0031903 microbody membrane; GO:0044429 mitochondrial part; GO:0044439 peroxisomal part; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005741 mitochondrial outer membrane; GO:0005777 peroxisome; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0016021 integral component of membrane; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044432 endoplasmic reticulum part; GO:0031975 envelope; GO:0005794 Golgi apparatus; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0016874 ligase activity; GO:0019901 protein kinase binding; GO:0016877 ligase activity, forming carbon-sulfur bonds; GO:0005515 protein binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0015645 fatty acid ligase activity; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0102391 decanoate--CoA ligase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0004467 long-chain fatty acid-CoA ligase activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0019900 kinase binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032555 purine ribonucleotide binding; GO:0019904 protein domain specific binding; GO:0001883 purine nucleoside binding; GO:0019899 enzyme binding; GO:0016878 acid-thiol ligase activity; GO:0036094 small molecule binding; ","K01897","ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]","hsa00061 Fatty acid biosynthesis - Homo sapiens (human); hsa04920 Adipocytokine signaling pathway - Homo sapiens (human); hsa03320 PPAR signaling pathway - Homo sapiens (human); hsa00071 Fatty acid degradation - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa01212 Fatty acid metabolism - Homo sapiens (human); hsa04216 Ferroptosis - Homo sapiens (human); hsa04146 Peroxisome - Homo sapiens (human); ","IPR000873; ","AMP-dependent synthetase/ligase; \r"]
["O95630","STAM-binding protein OS=Homo sapiens OX=9606 GN=STAMBP","STAMBP",48.076,3.8754,4.2,2,2,2,0.942,0.879,1.064,1.073,1.036,1.008,1.08,0.244,"cyto_nucl\r","GO:0044700 single organism signaling; GO:0070646 protein modification by small protein removal; GO:0010941 regulation of cell death; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0043523 regulation of neuron apoptotic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling; GO:0051056 regulation of small GTPase mediated signal transduction; GO:0051716 cellular response to stimulus; GO:0000278 mitotic cell cycle; GO:0097696 STAT cascade; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0070647 protein modification by small protein conjugation or removal; GO:0023052 signaling; GO:0050789 regulation of biological process; GO:1902532 negative regulation of intracellular signal transduction; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0051301 cell division; GO:0036211 protein modification process; GO:0060548 negative regulation of cell death; GO:0050794 regulation of cellular process; GO:0007259 JAK-STAT cascade; GO:0043069 negative regulation of programmed cell death; GO:0042127 regulation of cell proliferation; GO:0044267 cellular protein metabolic process; GO:0043067 regulation of programmed cell death; GO:0046578 regulation of Ras protein signal transduction; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0016579 protein deubiquitination; GO:1903047 mitotic cell cycle process; GO:0071704 organic substance metabolic process; GO:0014066 regulation of phosphatidylinositol 3-kinase signaling; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0000910 cytokinesis; GO:0043524 negative regulation of neuron apoptotic process; GO:0043066 negative regulation of apoptotic process; GO:0006508 proteolysis; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:1901214 regulation of neuron death; GO:1901215 negative regulation of neuron death; GO:0046580 negative regulation of Ras protein signal transduction; GO:1902531 regulation of intracellular signal transduction; GO:0035556 intracellular signal transduction; GO:0000281 mitotic cytokinesis; GO:0048585 negative regulation of response to stimulus; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0061640 cytoskeleton-dependent cytokinesis; GO:0022402 cell cycle process; GO:0043412 macromolecule modification; GO:0051058 negative regulation of small GTPase mediated signal transduction; GO:0007049 cell cycle; GO:0042981 regulation of apoptotic process; GO:0008284 positive regulation of cell proliferation; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0032155 cell division site part; GO:0044422 organelle part; GO:0005769 early endosome; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0032154 cleavage furrow; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0097610 cell surface furrow; GO:0032153 cell division site; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0009986 cell surface; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0004843 thiol-dependent ubiquitin-specific protease activity; GO:0008233 peptidase activity; GO:0043167 ion binding; GO:0019783 ubiquitin-like protein-specific protease activity; GO:0005515 protein binding; GO:0008237 metallopeptidase activity; GO:0008234 cysteine-type peptidase activity; GO:0016787 hydrolase activity; GO:0036459 thiol-dependent ubiquitinyl hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0101005 ubiquitinyl hydrolase activity; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0019904 protein domain specific binding; ","K11866","STAMBP; STAM-binding protein [EC:3.4.19.12]","hsa04144 Endocytosis - Homo sapiens (human); ","IPR015063; IPR000555; IPR007330; ","USP8 dimerisation domain; JAB1/MPN/MOV34 metalloenzyme domain; MIT; \r"]
["O95631","Netrin-1 OS=Homo sapiens OX=9606 GN=NTN1","NTN1",67.748,8.3998,2.5,1,1,1,1.173,0.945,0.951,1.233,0.872,0.85,0.963,0.75,"extracellular\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0048732 gland development; GO:0051647 nucleus localization; GO:0032989 cellular component morphogenesis; GO:0045927 positive regulation of growth; GO:0001558 regulation of cell growth; GO:0022610 biological adhesion; GO:0009605 response to external stimulus; GO:0048562 embryonic organ morphogenesis; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0032535 regulation of cellular component size; GO:0007155 cell adhesion; GO:0009790 embryo development; GO:0048598 embryonic morphogenesis; GO:0090596 sensory organ morphogenesis; GO:0006930 substrate-dependent cell migration, cell extension; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0030307 positive regulation of cell growth; GO:0031346 positive regulation of cell projection organization; GO:0048699 generation of neurons; GO:0035239 tube morphogenesis; GO:0045773 positive regulation of axon extension; GO:0044763 single-organism cellular process; GO:0048812 neuron projection morphogenesis; GO:0048870 cell motility; GO:0007264 small GTPase mediated signal transduction; GO:0051272 positive regulation of cellular component movement; GO:0032501 multicellular organismal process; GO:0006935 chemotaxis; GO:0050768 negative regulation of neurogenesis; GO:0000902 cell morphogenesis; GO:0048513 animal organ development; GO:0043583 ear development; GO:0098602 single organism cell adhesion; GO:0045665 negative regulation of neuron differentiation; GO:0009887 animal organ morphogenesis; GO:0042330 taxis; GO:0060603 mammary gland duct morphogenesis; GO:0010721 negative regulation of cell development; GO:0051094 positive regulation of developmental process; GO:0010975 regulation of neuron projection development; GO:0051640 organelle localization; GO:0050794 regulation of cellular process; GO:0002009 morphogenesis of an epithelium; GO:0044707 single-multicellular organism process; GO:0042127 regulation of cell proliferation; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:2000147 positive regulation of cell motility; GO:0045597 positive regulation of cell differentiation; GO:0051239 regulation of multicellular organismal process; GO:0030879 mammary gland development; GO:0009653 anatomical structure morphogenesis; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0050772 positive regulation of axonogenesis; GO:2000145 regulation of cell motility; GO:0007409 axonogenesis; GO:0031345 negative regulation of cell projection organization; GO:0060443 mammary gland morphogenesis; GO:0007275 multicellular organism development; GO:0060562 epithelial tube morphogenesis; GO:0010771 negative regulation of cell morphogenesis involved in differentiation; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0051960 regulation of nervous system development; GO:0060284 regulation of cell development; GO:0010977 negative regulation of neuron projection development; GO:0030334 regulation of cell migration; GO:0051656 establishment of organelle localization; GO:0048839 inner ear development; GO:0030031 cell projection assembly; GO:0050770 regulation of axonogenesis; GO:0030182 neuron differentiation; GO:0030516 regulation of axon extension; GO:0010976 positive regulation of neuron projection development; GO:0097485 neuron projection guidance; GO:0061387 regulation of extent of cell growth; GO:0006928 movement of cell or subcellular component; GO:0050769 positive regulation of neurogenesis; GO:0012501 programmed cell death; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:0051179 localization; GO:0007423 sensory organ development; GO:0050793 regulation of developmental process; GO:0008284 positive regulation of cell proliferation; GO:0051093 negative regulation of developmental process; GO:0045666 positive regulation of neuron differentiation; GO:0051674 localization of cell; GO:0048640 negative regulation of developmental growth; GO:0040017 positive regulation of locomotion; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0051129 negative regulation of cellular component organization; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0051241 negative regulation of multicellular organismal process; GO:0042472 inner ear morphogenesis; GO:0040023 establishment of nucleus localization; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0061180 mammary gland epithelium development; GO:0048729 tissue morphogenesis; GO:0016337 single organismal cell-cell adhesion; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0032990 cell part morphogenesis; GO:0006915 apoptotic process; GO:0007266 Rho protein signal transduction; GO:0048858 cell projection morphogenesis; GO:0001764 neuron migration; GO:0006929 substrate-dependent cell migration; GO:0010720 positive regulation of cell development; GO:0050771 negative regulation of axonogenesis; GO:0045596 negative regulation of cell differentiation; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0035295 tube development; GO:0045926 negative regulation of growth; GO:0009888 tissue development; GO:0048639 positive regulation of developmental growth; GO:0098609 cell-cell adhesion; GO:0051962 positive regulation of nervous system development; GO:0048522 positive regulation of cellular process; GO:0030517 negative regulation of axon extension; GO:0023052 signaling; GO:0030308 negative regulation of cell growth; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0030030 cell projection organization; GO:0045664 regulation of neuron differentiation; GO:0040011 locomotion; GO:0048856 anatomical structure development; GO:0007265 Ras protein signal transduction; GO:2000026 regulation of multicellular organismal development; GO:0016477 cell migration; GO:0016043 cellular component organization; GO:0033564 anterior/posterior axon guidance; GO:0040008 regulation of growth; GO:0048568 embryonic organ development; GO:0010770 positive regulation of cell morphogenesis involved in differentiation; GO:0031344 regulation of cell projection organization; GO:0048638 regulation of developmental growth; GO:0050896 response to stimulus; GO:0007411 axon guidance; GO:0048468 cell development; GO:0000904 cell morphogenesis involved in differentiation; GO:0030154 cell differentiation; GO:0008361 regulation of cell size; GO:0051961 negative regulation of nervous system development; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0035556 intracellular signal transduction; GO:0031175 neuron projection development; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0032488 Cdc42 protein signal transduction; GO:0061564 axon development; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0042471 ear morphogenesis; GO:0090066 regulation of anatomical structure size; GO:0051128 regulation of cellular component organization; GO:0040012 regulation of locomotion; GO:0022604 regulation of cell morphogenesis; GO:0022612 gland morphogenesis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:0050767 regulation of neurogenesis; ","GO:0031012 extracellular matrix; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0005578 proteinaceous extracellular matrix; GO:0044424 intracellular part; GO:0005623 cell; GO:0044420 extracellular matrix component; GO:0005576 extracellular region; GO:0005604 basement membrane; ","GO:0005515 protein binding; GO:0005488 binding; ","K06843","NTN1; netrin 1","hsa04360 Axon guidance - Homo sapiens (human); ","IPR008993; IPR001134; IPR002049; IPR008211; IPR018933; IPR008979; ","\"Tissue inhibitor of metalloproteinases-like, OB-fold; Netrin domain; Laminin EGF domain; Laminin, N-terminal; Netrin module, non-TIMP type; Galactose-binding domain-like; \"\r"]
["O95671","N-acetylserotonin O-methyltransferase-like protein OS=Homo sapiens OX=9606 GN=ASMTL","ASMTL",68.856,42.27,14,7,8,7,1.013,1.05,1.023,1.025,0.978,0.948,0.956,0.146,"mitochondria\r","GO:0008152 metabolic process; GO:0032259 methylation; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:0016462 pyrophosphatase activity; GO:0008168 methyltransferase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0047429 nucleoside-triphosphate diphosphatase activity; GO:0016741 transferase activity, transferring one-carbon groups; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0008171 O-methyltransferase activity; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0016740 transferase activity; ",{"$nulls":3},"IPR011991; IPR029063; IPR031725; IPR001077; ","\"Winged helix-turn-helix DNA-binding domain; S-adenosyl-L-methionine-dependent methyltransferase; Acetylserotonin O-methyltransferase, dimerisation domain; O-methyltransferase, family 2; \"\r"]
["O95674","Phosphatidate cytidylyltransferase 2 OS=Homo sapiens OX=9606 GN=CDS2","CDS2",51.417,14.176,7,2,2,2,1.04,1.174,1.199,0.876,0.857,0.877,0.765,0.00406,"plasma membrane\r","GO:0046486 glycerolipid metabolic process; GO:0044711 single-organism biosynthetic process; GO:0008654 phospholipid biosynthetic process; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044255 cellular lipid metabolic process; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:1901576 organic substance biosynthetic process; GO:0006796 phosphate-containing compound metabolic process; GO:0044249 cellular biosynthetic process; GO:0071704 organic substance metabolic process; GO:0008610 lipid biosynthetic process; GO:0045017 glycerolipid biosynthetic process; GO:0090407 organophosphate biosynthetic process; GO:0046471 phosphatidylglycerol metabolic process; GO:0008152 metabolic process; GO:0006793 phosphorus metabolic process; GO:0016024 CDP-diacylglycerol biosynthetic process; GO:0044710 single-organism metabolic process; GO:0046474 glycerophospholipid biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0006650 glycerophospholipid metabolic process; GO:0006655 phosphatidylglycerol biosynthetic process; GO:0006644 phospholipid metabolic process; GO:0046341 CDP-diacylglycerol metabolic process; GO:0009987 cellular process; GO:0006629 lipid metabolic process; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0044429 mitochondrial part; GO:0031090 organelle membrane; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0005740 mitochondrial envelope; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044432 endoplasmic reticulum part; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0031975 envelope; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0005789 endoplasmic reticulum membrane; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0070567 cytidylyltransferase activity; GO:0004605 phosphatidate cytidylyltransferase activity; GO:0016779 nucleotidyltransferase activity; GO:0003824 catalytic activity; GO:0016740 transferase activity; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K00981","E2.7.7.41; phosphatidate cytidylyltransferase [EC:2.7.7.41]","hsa00564 Glycerophospholipid metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa04070 Phosphatidylinositol signaling system - Homo sapiens (human); "]
["O95685","Protein phosphatase 1 regulatory subunit 3D OS=Homo sapiens OX=9606 GN=PPP1R3D","PPP1R3D",32.559,3.8608,5.4,1,1,1,0.954,0.996,0.962,1.027,1.036,1.03,1.062,0.0108,"mitochondria\r","GO:0050794 regulation of cellular process; GO:0043467 regulation of generation of precursor metabolites and energy; GO:0043255 regulation of carbohydrate biosynthetic process; GO:0005981 regulation of glycogen catabolic process; GO:0032885 regulation of polysaccharide biosynthetic process; GO:0060255 regulation of macromolecule metabolic process; GO:0044042 glucan metabolic process; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0006112 energy reserve metabolic process; GO:0010906 regulation of glucose metabolic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0044264 cellular polysaccharide metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0010962 regulation of glucan biosynthetic process; GO:0006091 generation of precursor metabolites and energy; GO:0044262 cellular carbohydrate metabolic process; GO:0009889 regulation of biosynthetic process; GO:0005976 polysaccharide metabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0009987 cellular process; GO:0043471 regulation of cellular carbohydrate catabolic process; GO:0031326 regulation of cellular biosynthetic process; GO:0006073 cellular glucan metabolic process; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0010675 regulation of cellular carbohydrate metabolic process; GO:0055114 oxidation-reduction process; GO:0009894 regulation of catabolic process; GO:0043470 regulation of carbohydrate catabolic process; GO:0044763 single-organism cellular process; GO:0005977 glycogen metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0006470 protein dephosphorylation; GO:0032881 regulation of polysaccharide metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0006109 regulation of carbohydrate metabolic process; GO:0044238 primary metabolic process; GO:0005975 carbohydrate metabolic process; GO:0016311 dephosphorylation; GO:0044723 single-organism carbohydrate metabolic process; GO:0050789 regulation of biological process; GO:0006793 phosphorus metabolic process; GO:0070873 regulation of glycogen metabolic process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006464 cellular protein modification process; GO:0005979 regulation of glycogen biosynthetic process; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0065007 biological regulation; ","GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0043229 intracellular organelle; GO:0042587 glycogen granule; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:0003824 catalytic activity; GO:0042578 phosphoric ester hydrolase activity; GO:0005488 binding; GO:0004722 protein serine/threonine phosphatase activity; GO:0016791 phosphatase activity; GO:0016788 hydrolase activity, acting on ester bonds; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0004721 phosphoprotein phosphatase activity; GO:0019899 enzyme binding; ","K07189","PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E","hsa04910 Insulin signaling pathway - Homo sapiens (human); hsa04931 Insulin resistance - Homo sapiens (human); ","IPR005036; ","CBM21 (carbohydrate binding type-21) domain; \r"]
["O95715","C-X-C motif chemokine 14 OS=Homo sapiens OX=9606 GN=CXCL14","CXCL14",13.077,2.5169,14.4,2,2,2,0.884,0.817,0.81,1.038,1.22,1.215,1.383,0.0058,"extracellular\r","GO:0044700 single organism signaling; GO:0051093 negative regulation of developmental process; GO:0030335 positive regulation of cell migration; GO:0051674 localization of cell; GO:0040017 positive regulation of locomotion; GO:0044699 single-organism process; GO:0009605 response to external stimulus; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0045661 regulation of myoblast differentiation; GO:0032879 regulation of localization; GO:0032103 positive regulation of response to external stimulus; GO:0045662 negative regulation of myoblast differentiation; GO:0050921 positive regulation of chemotaxis; GO:0045596 negative regulation of cell differentiation; GO:0070887 cellular response to chemical stimulus; GO:0051147 regulation of muscle cell differentiation; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0044763 single-organism cellular process; GO:2000501 regulation of natural killer cell chemotaxis; GO:0048522 positive regulation of cellular process; GO:0002688 regulation of leukocyte chemotaxis; GO:0048870 cell motility; GO:0051272 positive regulation of cellular component movement; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0006935 chemotaxis; GO:0048513 animal organ development; GO:0043583 ear development; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0007267 cell-cell signaling; GO:1901623 regulation of lymphocyte chemotaxis; GO:0048583 regulation of response to stimulus; GO:0042330 taxis; GO:0051148 negative regulation of muscle cell differentiation; GO:0002682 regulation of immune system process; GO:0040011 locomotion; GO:0002685 regulation of leukocyte migration; GO:0048856 anatomical structure development; GO:0002687 positive regulation of leukocyte migration; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0016477 cell migration; GO:2000147 positive regulation of cell motility; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0060326 cell chemotaxis; GO:0050896 response to stimulus; GO:0002690 positive regulation of leukocyte chemotaxis; GO:2000145 regulation of cell motility; GO:2000403 positive regulation of lymphocyte migration; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0002376 immune system process; GO:0030334 regulation of cell migration; GO:0032101 regulation of response to external stimulus; GO:0048839 inner ear development; GO:0050920 regulation of chemotaxis; GO:0048518 positive regulation of biological process; GO:2000503 positive regulation of natural killer cell chemotaxis; GO:2000401 regulation of lymphocyte migration; GO:0044767 single-organism developmental process; GO:0002684 positive regulation of immune system process; GO:0006928 movement of cell or subcellular component; GO:0006955 immune response; GO:0007423 sensory organ development; GO:0040012 regulation of locomotion; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0065007 biological regulation; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0005794 Golgi apparatus; GO:0005576 extracellular region; GO:0044444 cytoplasmic part; ","GO:0005125 cytokine activity; GO:0005102 receptor binding; GO:0005488 binding; GO:0042379 chemokine receptor binding; GO:0005126 cytokine receptor binding; GO:0005515 protein binding; GO:0001664 G-protein coupled receptor binding; GO:0008009 chemokine activity; ","K10033","CXCL14; C-X-C motif chemokine 14","hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human); hsa04062 Chemokine signaling pathway - Homo sapiens (human); ","IPR001811; ","Chemokine interleukin-8-like domain; \r"]
["O95716","Ras-related protein Rab-3D OS=Homo sapiens OX=9606 GN=RAB3D","RAB3D",24.267,15.771,15.5,3,7,2,0.869,0.882,0.862,1.135,1.109,1.135,1.293,1.75e-05,"cytoplasm\r","GO:0044700 single organism signaling; GO:0060627 regulation of vesicle-mediated transport; GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0044699 single-organism process; GO:0051046 regulation of secretion; GO:0044237 cellular metabolic process; GO:0032259 methylation; GO:0048871 multicellular organismal homeostasis; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0008213 protein alkylation; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:1903307 positive regulation of regulated secretory pathway; GO:0032879 regulation of localization; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0045921 positive regulation of exocytosis; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0007264 small GTPase mediated signal transduction; GO:1903530 regulation of secretion by cell; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0002444 myeloid leukocyte mediated immunity; GO:0051050 positive regulation of transport; GO:0006810 transport; GO:0050789 regulation of biological process; GO:1903532 positive regulation of secretion by cell; GO:0018198 peptidyl-cysteine modification; GO:0032940 secretion by cell; GO:0001894 tissue homeostasis; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0043299 leukocyte degranulation; GO:0036211 protein modification process; GO:0051047 positive regulation of secretion; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0044267 cellular protein metabolic process; GO:0017157 regulation of exocytosis; GO:0050896 response to stimulus; GO:0060249 anatomical structure homeostasis; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0006479 protein methylation; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0048771 tissue remodeling; GO:0035556 intracellular signal transduction; GO:0051049 regulation of transport; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:1903305 regulation of regulated secretory pathway; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0002263 cell activation involved in immune response; GO:0018193 peptidyl-amino acid modification; GO:0002366 leukocyte activation involved in immune response; GO:0045184 establishment of protein localization; GO:0045453 bone resorption; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0043414 macromolecule methylation; GO:0018125 peptidyl-cysteine methylation; GO:0001775 cell activation; GO:0043412 macromolecule modification; GO:0006955 immune response; GO:0051179 localization; GO:0046849 bone remodeling; GO:0065007 biological regulation; GO:0006887 exocytosis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005874 microtubule; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0005881 cytoplasmic microtubule; GO:0071944 cell periphery; GO:0042588 zymogen granule; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0099512 supramolecular fiber; GO:0005623 cell; GO:0099080 supramolecular complex; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005765 lysosomal membrane; GO:0005856 cytoskeleton; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0099513 polymeric cytoskeletal fiber; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0035577 azurophil granule membrane; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0099081 supramolecular polymer; GO:0030659 cytoplasmic vesicle membrane; GO:0098852 lytic vacuole membrane; GO:0042582 azurophil granule; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0030667 secretory granule membrane; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0030133 transport vesicle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0031489 myosin V binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0008092 cytoskeletal protein binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0003924 GTPase activity; GO:0043168 anion binding; GO:0019001 guanyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0030742 GTP-dependent protein binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0032561 guanyl ribonucleotide binding; GO:0017022 myosin binding; GO:0036094 small molecule binding; ","K07884","RAB3D; Ras-related protein Rab-3D","hsa04972 Pancreatic secretion - Homo sapiens (human); ","IPR005225; IPR027417; ","Small GTP-binding protein domain; P-loop containing nucleoside triphosphate hydrolase; \r"]
["O95721","Synaptosomal-associated protein 29 OS=Homo sapiens OX=9606 GN=SNAP29","SNAP29",28.97,5.4749,8.5,2,3,2,0.991,0.968,0.895,1.071,1.054,1.026,1.104,0.0399,"cytoplasm\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0001505 regulation of neurotransmitter levels; GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0007269 neurotransmitter secretion; GO:0060271 cilium assembly; GO:0044699 single-organism process; GO:0006914 autophagy; GO:0044237 cellular metabolic process; GO:0099504 synaptic vesicle cycle; GO:0015031 protein transport; GO:0044782 cilium organization; GO:0051234 establishment of localization; GO:0099003 vesicle-mediated transport in synapse; GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0098916 anterograde trans-synaptic signaling; GO:0007033 vacuole organization; GO:0044801 single-organism membrane fusion; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0002274 myeloid leukocyte activation; GO:0099500 vesicle fusion to plasma membrane; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0016236 macroautophagy; GO:0051650 establishment of vesicle localization; GO:0002443 leukocyte mediated immunity; GO:0048489 synaptic vesicle transport; GO:0071822 protein complex subunit organization; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0061025 membrane fusion; GO:0023052 signaling; GO:0002444 myeloid leukocyte mediated immunity; GO:1902582 single-organism intracellular transport; GO:0006810 transport; GO:1902589 single-organism organelle organization; GO:0007267 cell-cell signaling; GO:0030030 cell projection organization; GO:0032940 secretion by cell; GO:0016082 synaptic vesicle priming; GO:0006906 vesicle fusion; GO:0043299 leukocyte degranulation; GO:0045026 plasma membrane fusion; GO:0070271 protein complex biogenesis; GO:0099643 signal release from synapse; GO:0051640 organelle localization; GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0090174 organelle membrane fusion; GO:0002283 neutrophil activation involved in immune response; GO:0016240 autophagosome docking; GO:0002252 immune effector process; GO:0097352 autophagosome maturation; GO:0099531 presynaptic process involved in chemical synaptic transmission; GO:0006903 vesicle targeting; GO:0050896 response to stimulus; GO:0022406 membrane docking; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0070925 organelle assembly; GO:0051648 vesicle localization; GO:0044248 cellular catabolic process; GO:0099537 trans-synaptic signaling; GO:1902580 single-organism cellular localization; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0043623 cellular protein complex assembly; GO:0034622 cellular macromolecular complex assembly; GO:0017156 calcium ion regulated exocytosis; GO:0016192 vesicle-mediated transport; GO:0044802 single-organism membrane organization; GO:0016079 synaptic vesicle exocytosis; GO:0016050 vesicle organization; GO:0002376 immune system process; GO:0023061 signal release; GO:0048284 organelle fusion; GO:0071702 organic substance transport; GO:0043312 neutrophil degranulation; GO:0051656 establishment of organelle localization; GO:0002263 cell activation involved in immune response; GO:0030031 cell projection assembly; GO:0043933 macromolecular complex subunit organization; GO:0097480 establishment of synaptic vesicle localization; GO:0051641 cellular localization; GO:0002366 leukocyte activation involved in immune response; GO:0045184 establishment of protein localization; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0099536 synaptic signaling; GO:0097576 vacuole fusion; GO:0097479 synaptic vesicle localization; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0001775 cell activation; GO:0006955 immune response; GO:0007268 chemical synaptic transmission; GO:0051179 localization; GO:0009056 catabolic process; GO:0006836 neurotransmitter transport; GO:0006887 exocytosis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005765 lysosomal membrane; GO:0005654 nucleoplasm; GO:0098590 plasma membrane region; GO:0005622 intracellular; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:0043227 membrane-bounded organelle; GO:0020016 ciliary pocket; GO:0031201 SNARE complex; GO:0097458 neuron part; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0005929 cilium; GO:0042995 cell projection; GO:0044430 cytoskeletal part; GO:0035577 azurophil granule membrane; GO:0012506 vesicle membrane; GO:0031981 nuclear lumen; GO:0005886 plasma membrane; GO:0042582 azurophil granule; GO:0043231 intracellular membrane-bounded organelle; GO:0030667 secretory granule membrane; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043234 protein complex; GO:0060170 ciliary membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005776 autophagosome; GO:0005856 cytoskeleton; GO:0031974 membrane-enclosed lumen; GO:0005815 microtubule organizing center; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0044441 ciliary part; GO:0044464 cell part; GO:0044425 membrane part; GO:0098793 presynapse; GO:0098805 whole membrane; GO:0044431 Golgi apparatus part; GO:0030141 secretory granule; GO:0044456 synapse part; GO:0000421 autophagosome membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0045202 synapse; GO:0030659 cytoplasmic vesicle membrane; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0005813 centrosome; GO:0031253 cell projection membrane; GO:0005774 vacuolar membrane; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; GO:0020018 ciliary pocket membrane; GO:0044428 nuclear part; ","GO:0000149 SNARE binding; GO:0005484 SNAP receptor activity; GO:0005515 protein binding; GO:0019905 syntaxin binding; GO:0005488 binding; ","K08509","SNAP29; synaptosomal-associated protein 29","hsa04130 SNARE interactions in vesicular transport - Homo sapiens (human); hsa04140 Autophagy - animal - Homo sapiens (human); ","IPR000727; ","Target SNARE coiled-coil homology domain; \r"]
["O95747","Serine/threonine-protein kinase OSR1 OS=Homo sapiens OX=9606 GN=OXSR1","OXSR1",58.022,38.368,13.9,7,9,5,0.997,0.952,0.897,1.074,0.986,1.053,1.094,0.088,"cytoplasm\r","GO:0044700 single organism signaling; GO:2000681 negative regulation of rubidium ion transport; GO:1901017 negative regulation of potassium ion transmembrane transporter activity; GO:0044699 single-organism process; GO:0006971 hypotonic response; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0043266 regulation of potassium ion transport; GO:0007154 cell communication; GO:0032879 regulation of localization; GO:0006979 response to oxidative stress; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0032413 negative regulation of ion transmembrane transporter activity; GO:0051051 negative regulation of transport; GO:0051716 cellular response to stimulus; GO:0006970 response to osmotic stress; GO:0071214 cellular response to abiotic stimulus; GO:0043269 regulation of ion transport; GO:0044763 single-organism cellular process; GO:0022898 regulation of transmembrane transporter activity; GO:0023052 signaling; GO:0034762 regulation of transmembrane transport; GO:0050789 regulation of biological process; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0071470 cellular response to osmotic stress; GO:0065009 regulation of molecular function; GO:1901016 regulation of potassium ion transmembrane transporter activity; GO:0044092 negative regulation of molecular function; GO:0006464 cellular protein modification process; GO:0032412 regulation of ion transmembrane transporter activity; GO:0036211 protein modification process; GO:0050794 regulation of cellular process; GO:0016310 phosphorylation; GO:0043267 negative regulation of potassium ion transport; GO:0033554 cellular response to stress; GO:2000680 regulation of rubidium ion transport; GO:1901380 negative regulation of potassium ion transmembrane transport; GO:0018210 peptidyl-threonine modification; GO:0009628 response to abiotic stimulus; GO:0044267 cellular protein metabolic process; GO:2000686 regulation of rubidium ion transmembrane transporter activity; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0006468 protein phosphorylation; GO:0032410 negative regulation of transporter activity; GO:0018107 peptidyl-threonine phosphorylation; GO:0010959 regulation of metal ion transport; GO:0009987 cellular process; GO:1904062 regulation of cation transmembrane transport; GO:0032409 regulation of transporter activity; GO:0023014 signal transduction by protein phosphorylation; GO:0034763 negative regulation of transmembrane transport; GO:0043271 negative regulation of ion transport; GO:0006950 response to stress; GO:0035556 intracellular signal transduction; GO:0051049 regulation of transport; GO:1901379 regulation of potassium ion transmembrane transport; GO:0071476 cellular hypotonic response; GO:0044238 primary metabolic process; GO:0034766 negative regulation of ion transmembrane transport; GO:0018193 peptidyl-amino acid modification; GO:1904063 negative regulation of cation transmembrane transport; GO:2000687 negative regulation of rubidium ion transmembrane transporter activity; GO:0034765 regulation of ion transmembrane transport; GO:0006793 phosphorus metabolic process; GO:0043412 macromolecule modification; GO:0065007 biological regulation; ","GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0005515 protein binding; GO:0004672 protein kinase activity; GO:0004702 signal transducer, downstream of receptor, with serine/threonine kinase activity; GO:0004871 signal transducer activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0016301 kinase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0000287 magnesium ion binding; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0005057 signal transducer activity, downstream of receptor; GO:0046872 metal ion binding; GO:0004674 protein serine/threonine kinase activity; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K08835",null,null,"IPR000719; IPR024678; IPR011009; ","\"Protein kinase domain; Serine/threonine-protein kinase OSR1/WNK, CCT domain; Protein kinase-like domain; \"\r"]
["O95749","Geranylgeranyl pyrophosphate synthase OS=Homo sapiens OX=9606 GN=GGPS1","GGPS1",34.87,5.2613,9.3,3,4,3,1.107,1.103,1.064,0.905,0.895,0.946,0.839,1.14E-3,"cytoplasm\r","GO:0033385 geranylgeranyl diphosphate metabolic process; GO:1901615 organic hydroxy compound metabolic process; GO:0033384 geranyl diphosphate biosynthetic process; GO:1902652 secondary alcohol metabolic process; GO:0006066 alcohol metabolic process; GO:1902653 secondary alcohol biosynthetic process; GO:0008654 phospholipid biosynthetic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044255 cellular lipid metabolic process; GO:0016125 sterol metabolic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0008610 lipid biosynthetic process; GO:0008299 isoprenoid biosynthetic process; GO:0016126 sterol biosynthetic process; GO:0008152 metabolic process; GO:0006695 cholesterol biosynthetic process; GO:0016114 terpenoid biosynthetic process; GO:0009987 cellular process; GO:0045338 farnesyl diphosphate metabolic process; GO:0033386 geranylgeranyl diphosphate biosynthetic process; GO:0006629 lipid metabolic process; GO:0006720 isoprenoid metabolic process; GO:0045337 farnesyl diphosphate biosynthetic process; GO:0008203 cholesterol metabolic process; GO:0044711 single-organism biosynthetic process; GO:0044281 small molecule metabolic process; GO:0008202 steroid metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0046165 alcohol biosynthetic process; GO:1901617 organic hydroxy compound biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0006694 steroid biosynthetic process; GO:0090407 organophosphate biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0044283 small molecule biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0006721 terpenoid metabolic process; GO:0006644 phospholipid metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0033383 geranyl diphosphate metabolic process; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0044444 cytoplasmic part; ","GO:0004337 geranyltranstransferase activity; GO:0004659 prenyltransferase activity; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0004311 farnesyltranstransferase activity; GO:0005515 protein binding; GO:0004161 dimethylallyltranstransferase activity; GO:0016740 transferase activity; ","K00804","GGPS1; geranylgeranyl diphosphate synthase, type III [EC:2.5.1.1 2.5.1.10 2.5.1.29]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00900 Terpenoid backbone biosynthesis - Homo sapiens (human); ","IPR008949; ","Isoprenoid synthase domain; \r"]
["O95757","Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L","HSPA4L",94.511,51.427,20.4,13,18,10,0.807,0.892,0.807,1.134,1.232,1.065,1.369,0.00432,"cytoplasm\r","GO:0006457 protein folding; GO:0006986 response to unfolded protein; GO:0035966 response to topologically incorrect protein; GO:0042221 response to chemical; GO:0006950 response to stress; GO:0010033 response to organic substance; GO:0050896 response to stimulus; GO:0009987 cellular process; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K09485","HSP110; heat shock protein 110kDa","hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); ","IPR029048; IPR029047; ","\"Heat shock protein 70kD, C-terminal domain; Heat shock protein 70kD, peptide-binding domain; \"\r"]
["O95760","Interleukin-33 OS=Homo sapiens OX=9606 GN=IL33","IL33",30.759,2.9432,6.3,2,2,2,0.997,1.37,0.979,0.872,1.028,0.785,0.802,0.187,"nucleus\r","GO:0044700 single organism signaling; GO:0002694 regulation of leukocyte activation; GO:0045321 leukocyte activation; GO:0032270 positive regulation of cellular protein metabolic process; GO:0007166 cell surface receptor signaling pathway; GO:0097659 nucleic acid-templated transcription; GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0032656 regulation of interleukin-13 production; GO:0098542 defense response to other organism; GO:0009891 positive regulation of biosynthetic process; GO:0002698 negative regulation of immune effector process; GO:0032754 positive regulation of interleukin-5 production; GO:0031347 regulation of defense response; GO:0044237 cellular metabolic process; GO:0009607 response to biotic stimulus; GO:0009605 response to external stimulus; GO:1903364 positive regulation of cellular protein catabolic process; GO:0008152 metabolic process; GO:0042116 macrophage activation; GO:0032673 regulation of interleukin-4 production; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0044419 interspecies interaction between organisms; GO:1903362 regulation of cellular protein catabolic process; GO:0051051 negative regulation of transport; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0050709 negative regulation of protein secretion; GO:0050729 positive regulation of inflammatory response; GO:0080090 regulation of primary metabolic process; GO:0002639 positive regulation of immunoglobulin production; GO:0031329 regulation of cellular catabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0009894 regulation of catabolic process; GO:1903531 negative regulation of secretion by cell; GO:0044763 single-organism cellular process; GO:0050707 regulation of cytokine secretion; GO:0032774 RNA biosynthetic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0031323 regulation of cellular metabolic process; GO:2000146 negative regulation of cell motility; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0002701 negative regulation of production of molecular mediator of immune response; GO:0050776 regulation of immune response; GO:1903506 regulation of nucleic acid-templated transcription; GO:0042063 gliogenesis; GO:0048583 regulation of response to stimulus; GO:0061517 macrophage proliferation; GO:0061136 regulation of proteasomal protein catabolic process; GO:0050714 positive regulation of protein secretion; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051223 regulation of protein transport; GO:0006464 cellular protein modification process; GO:0002682 regulation of immune system process; GO:0002685 regulation of leukocyte migration; GO:0032736 positive regulation of interleukin-13 production; GO:0051023 regulation of immunoglobulin secretion; GO:1901362 organic cyclic compound biosynthetic process; GO:0051047 positive regulation of secretion; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0097191 extrinsic apoptotic signaling pathway; GO:0097190 apoptotic signaling pathway; GO:0001819 positive regulation of cytokine production; GO:0044267 cellular protein metabolic process; GO:0080134 regulation of response to stress; GO:0061518 microglial cell proliferation; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0051239 regulation of multicellular organismal process; GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0050867 positive regulation of cell activation; GO:0031349 positive regulation of defense response; GO:0046483 heterocycle metabolic process; GO:0002275 myeloid cell activation involved in immune response; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:2000145 regulation of cell motility; GO:0009896 positive regulation of catabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0090196 regulation of chemokine secretion; GO:0032880 regulation of protein localization; GO:0007275 multicellular organism development; GO:0042176 regulation of protein catabolic process; GO:0050778 positive regulation of immune response; GO:0051254 positive regulation of RNA metabolic process; GO:0006950 response to stress; GO:0051224 negative regulation of protein transport; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0032675 regulation of interleukin-6 production; GO:0032101 regulation of response to external stimulus; GO:0002376 immune system process; GO:0008283 cell proliferation; GO:0030334 regulation of cell migration; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0002263 cell activation involved in immune response; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0002696 positive regulation of leukocyte activation; GO:0002638 negative regulation of immunoglobulin production; GO:0051247 positive regulation of protein metabolic process; GO:1904951 positive regulation of establishment of protein localization; GO:0030336 negative regulation of cell migration; GO:0031325 positive regulation of cellular metabolic process; GO:0002828 regulation of type 2 immune response; GO:0001775 cell activation; GO:0012501 programmed cell death; GO:0048584 positive regulation of response to stimulus; GO:0006955 immune response; GO:0031328 positive regulation of cellular biosynthetic process; GO:0043412 macromolecule modification; GO:0032689 negative regulation of interferon-gamma production; GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process; GO:0002702 positive regulation of production of molecular mediator of immune response; GO:0070646 protein modification by small protein removal; GO:0043030 regulation of macrophage activation; GO:0031331 positive regulation of cellular catabolic process; GO:0048869 cellular developmental process; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0051046 regulation of secretion; GO:0009058 biosynthetic process; GO:0002825 regulation of T-helper 1 type immune response; GO:0044764 multi-organism cellular process; GO:0001818 negative regulation of cytokine production; GO:0032753 positive regulation of interleukin-4 production; GO:0040013 negative regulation of locomotion; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0032674 regulation of interleukin-5 production; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0032642 regulation of chemokine production; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0002819 regulation of adaptive immune response; GO:0032103 positive regulation of response to external stimulus; GO:0006915 apoptotic process; GO:0051025 negative regulation of immunoglobulin secretion; GO:0050777 negative regulation of immune response; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0002697 regulation of immune effector process; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0051024 positive regulation of immunoglobulin secretion; GO:0002700 regulation of production of molecular mediator of immune response; GO:0070647 protein modification by small protein conjugation or removal; GO:0023052 signaling; GO:1903530 regulation of secretion by cell; GO:0051050 positive regulation of transport; GO:0016070 RNA metabolic process; GO:0002826 negative regulation of T-helper 1 type immune response; GO:0002683 negative regulation of immune system process; GO:0002820 negative regulation of adaptive immune response; GO:0051048 negative regulation of secretion; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0050865 regulation of cell activation; GO:0090304 nucleic acid metabolic process; GO:0051607 defense response to virus; GO:0006351 transcription, DNA-templated; GO:1903532 positive regulation of secretion by cell; GO:0070661 leukocyte proliferation; GO:0019222 regulation of metabolic process; GO:0002830 positive regulation of type 2 immune response; GO:0006952 defense response; GO:0014009 glial cell proliferation; GO:0036211 protein modification process; GO:0050715 positive regulation of cytokine secretion; GO:0048856 anatomical structure development; GO:0009615 response to virus; GO:0032722 positive regulation of chemokine production; GO:0051222 positive regulation of protein transport; GO:0051271 negative regulation of cellular component movement; GO:0002686 negative regulation of leukocyte migration; GO:0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0006725 cellular aromatic compound metabolic process; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0016579 protein deubiquitination; GO:0001774 microglial cell activation; GO:0051707 response to other organism; GO:0070201 regulation of establishment of protein localization; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0043032 positive regulation of macrophage activation; GO:0045862 positive regulation of proteolysis; GO:0016032 viral process; GO:0034641 cellular nitrogen compound metabolic process; GO:0006508 proteolysis; GO:0009059 macromolecule biosynthetic process; GO:0050708 regulation of protein secretion; GO:0009987 cellular process; GO:0032649 regulation of interferon-gamma production; GO:0032755 positive regulation of interleukin-6 production; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0042092 type 2 immune response; GO:0090197 positive regulation of chemokine secretion; GO:0051049 regulation of transport; GO:0002699 positive regulation of immune effector process; GO:1901800 positive regulation of proteasomal protein catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0002281 macrophage activation involved in immune response; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0002366 leukocyte activation involved in immune response; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0008219 cell death; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0002684 positive regulation of immune system process; GO:0002637 regulation of immunoglobulin production; GO:0050727 regulation of inflammatory response; GO:0001817 regulation of cytokine production; GO:0010467 gene expression; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:1904950 negative regulation of establishment of protein localization; GO:0045732 positive regulation of protein catabolic process; GO:0040012 regulation of locomotion; GO:0002282 microglial cell activation involved in immune response; GO:0065007 biological regulation; ","GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0030133 transport vesicle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005125 cytokine activity; GO:0005515 protein binding; GO:0005102 receptor binding; GO:0005488 binding; ","K12967","IL33; interleukin 33","hsa04623 Cytosolic DNA-sensing pathway - Homo sapiens (human); hsa04217 Necroptosis - Homo sapiens (human); hsa05164 Influenza A - Homo sapiens (human); "]
["O95777","U6 snRNA-associated Sm-like protein LSm8 OS=Homo sapiens OX=9606 GN=LSM8","LSM8",10.403,16.605,27.1,2,3,2,1.202,1.05,1.096,0.984,0.855,0.841,0.8,0.0249,"cytoplasm\r","GO:0006396 RNA processing; GO:0006725 cellular aromatic compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0008152 metabolic process; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0090304 nucleic acid metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0016071 mRNA metabolic process; ","GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0046540 U4/U6 x U5 tri-snRNP complex; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005681 spliceosomal complex; GO:0005623 cell; GO:0044422 organelle part; GO:0097525 spliceosomal snRNP complex; GO:0097526 spliceosomal tri-snRNP complex; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:1990904 ribonucleoprotein complex; GO:0005688 U6 snRNP; GO:0030529 intracellular ribonucleoprotein complex; GO:0030532 small nuclear ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0017070 U6 snRNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0017069 snRNA binding; ","K12627","LSM8; U6 snRNA-associated Sm-like protein LSm8","hsa03018 RNA degradation - Homo sapiens (human); hsa03040 Spliceosome - Homo sapiens (human); ","IPR001163; IPR034103; IPR010920; ","\"LSM domain, eukaryotic/archaea-type; Sm-like protein Lsm8; LSM domain; \"\r"]
["O95782","AP-2 complex subunit alpha-1 OS=Homo sapiens OX=9606 GN=AP2A1","AP2A1",107.54,57.878,24.6,21,33,13,1.009,1.004,1.031,0.98,1.005,0.972,0.971,0.0881,"cytoplasm\r","GO:0044700 single organism signaling; GO:0032885 regulation of polysaccharide biosynthetic process; GO:0007166 cell surface receptor signaling pathway; GO:0044699 single-organism process; GO:0031347 regulation of defense response; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0035567 non-canonical Wnt signaling pathway; GO:1900126 negative regulation of hyaluronan biosynthetic process; GO:1905330 regulation of morphogenesis of an epithelium; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0050690 regulation of defense response to virus by virus; GO:1900125 regulation of hyaluronan biosynthetic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0016055 Wnt signaling pathway; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0002697 regulation of immune effector process; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0051716 cellular response to stimulus; GO:0006895 Golgi to endosome transport; GO:0080090 regulation of primary metabolic process; GO:0048002 antigen processing and presentation of peptide antigen; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0023052 signaling; GO:0002495 antigen processing and presentation of peptide antigen via MHC class II; GO:0010605 negative regulation of macromolecule metabolic process; GO:0198738 cell-cell signaling by wnt; GO:0016197 endosomal transport; GO:0006810 transport; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0050789 regulation of biological process; GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0007267 cell-cell signaling; GO:0048583 regulation of response to stimulus; GO:0060071 Wnt signaling pathway, planar cell polarity pathway; GO:0019222 regulation of metabolic process; GO:0002682 regulation of immune system process; GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:2000026 regulation of multicellular organismal development; GO:0050794 regulation of cellular process; GO:0090175 regulation of establishment of planar polarity; GO:0016043 cellular component organization; GO:0043255 regulation of carbohydrate biosynthetic process; GO:0046907 intracellular transport; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0002831 regulation of response to biotic stimulus; GO:0060255 regulation of macromolecule metabolic process; GO:0048193 Golgi vesicle transport; GO:0048519 negative regulation of biological process; GO:0080134 regulation of response to stress; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:0050688 regulation of defense response to virus; GO:0072583 clathrin-dependent endocytosis; GO:2000027 regulation of organ morphogenesis; GO:0048013 ephrin receptor signaling pathway; GO:0009889 regulation of biosynthetic process; GO:0006886 intracellular protein transport; GO:0051171 regulation of nitrogen compound metabolic process; GO:0006898 receptor-mediated endocytosis; GO:0016482 cytosolic transport; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0016192 vesicle-mediated transport; GO:0043900 regulation of multi-organism process; GO:0050792 regulation of viral process; GO:0002376 immune system process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0071702 organic substance transport; GO:0032101 regulation of response to external stimulus; GO:0006109 regulation of carbohydrate metabolic process; GO:0032881 regulation of polysaccharide metabolic process; GO:0006897 endocytosis; GO:0007017 microtubule-based process; GO:0009892 negative regulation of metabolic process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0019882 antigen processing and presentation; GO:0007018 microtubule-based movement; GO:0009890 negative regulation of biosynthetic process; GO:0070727 cellular macromolecule localization; GO:0045912 negative regulation of carbohydrate metabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0061024 membrane organization; GO:0006928 movement of cell or subcellular component; GO:0006892 post-Golgi vesicle-mediated transport; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0030119 AP-type membrane coat adaptor complex; GO:0045334 clathrin-coated endocytic vesicle; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0036019 endolysosome; GO:0098858 actin-based cell projection; GO:0005623 cell; GO:0044422 organelle part; GO:0005765 lysosomal membrane; GO:0098590 plasma membrane region; GO:0030136 clathrin-coated vesicle; GO:0005622 intracellular; GO:0005764 lysosome; GO:0098589 membrane region; GO:0030175 filopodium; GO:0012510 trans-Golgi network transport vesicle membrane; GO:0043227 membrane-bounded organelle; GO:0045177 apical part of cell; GO:0000323 lytic vacuole; GO:0010008 endosome membrane; GO:0042995 cell projection; GO:0030666 endocytic vesicle membrane; GO:0036020 endolysosome membrane; GO:0048475 coated membrane; GO:0098797 plasma membrane protein complex; GO:0032433 filopodium tip; GO:0044440 endosomal part; GO:0012506 vesicle membrane; GO:0030135 coated vesicle; GO:0005798 Golgi-associated vesicle; GO:0005886 plasma membrane; GO:0030125 clathrin vesicle coat; GO:0043231 intracellular membrane-bounded organelle; GO:0030122 AP-2 adaptor complex; GO:0030131 clathrin adaptor complex; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0030118 clathrin coat; GO:0030117 membrane coat; GO:0005905 clathrin-coated pit; GO:0043234 protein complex; GO:0030133 transport vesicle; GO:0016323 basolateral plasma membrane; GO:0030658 transport vesicle membrane; GO:0030130 clathrin coat of trans-Golgi network vesicle; GO:0016324 apical plasma membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0030660 Golgi-associated vesicle membrane; GO:0031982 vesicle; GO:0030669 clathrin-coated endocytic vesicle membrane; GO:0044424 intracellular part; GO:0030120 vesicle coat; GO:0030662 coated vesicle membrane; GO:0030140 trans-Golgi network transport vesicle; GO:0044425 membrane part; GO:0044464 cell part; GO:0098805 whole membrane; GO:0044431 Golgi apparatus part; GO:0005768 endosome; GO:0030132 clathrin coat of coated pit; GO:0030139 endocytic vesicle; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0030665 clathrin-coated vesicle membrane; GO:0030128 clathrin coat of endocytic vesicle; GO:0098852 lytic vacuole membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0005774 vacuolar membrane; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:0008565 protein transporter activity; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0019901 protein kinase binding; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0008022 protein C-terminus binding; GO:0019900 kinase binding; GO:0019899 enzyme binding; GO:0032403 protein complex binding; GO:0005215 transporter activity; ","K11824","AP2A; AP-2 complex subunit alpha","hsa05016 Huntington's disease - Homo sapiens (human); hsa04144 Endocytosis - Homo sapiens (human); hsa04961 Endocrine and other factor-regulated calcium reabsorption - Homo sapiens (human); hsa04721 Synaptic vesicle cycle - Homo sapiens (human); ","IPR008152; IPR011989; IPR013038; IPR002553; IPR003164; IPR016024; IPR015873; IPR009028; IPR013041; ","\"Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain; Armadillo-like helical; Clathrin adaptor, alpha-adaptin, appendage, Ig-like subdomain; Clathrin/coatomer adaptor, adaptin-like, N-terminal; Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain; Armadillo-type fold; Clathrin alpha-adaptin/coatomer adaptor, appendage, C-terminal subdomain; Coatomer/calthrin adaptor appendage, C-terminal subdomain; Coatomer/clathrin adaptor appendage, Ig-like subdomain; \"\r"]
["O95786","Probable ATP-dependent RNA helicase DDX58 OS=Homo sapiens OX=9606 GN=DDX58","DDX58",106.6,20.866,8.6,8,10,8,0.897,0.842,0.869,1.056,1.084,1.168,1.268,0.00256,"cytoplasm\r","GO:0044700 single organism signaling; GO:0032481 positive regulation of type I interferon production; GO:1903533 regulation of protein targeting; GO:0032647 regulation of interferon-alpha production; GO:0009891 positive regulation of biosynthetic process; GO:0098542 defense response to other organism; GO:0031347 regulation of defense response; GO:0044237 cellular metabolic process; GO:0009607 response to biotic stimulus; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0030522 intracellular receptor signaling pathway; GO:0039529 RIG-I signaling pathway; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0002758 innate immune response-activating signal transduction; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0031323 regulation of cellular metabolic process; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:1903506 regulation of nucleic acid-templated transcription; GO:0051090 regulation of sequence-specific DNA binding transcription factor activity; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051223 regulation of protein transport; GO:0002682 regulation of immune system process; GO:0006464 cellular protein modification process; GO:0042307 positive regulation of protein import into nucleus; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0032677 regulation of interleukin-8 production; GO:0002753 cytoplasmic pattern recognition receptor signaling pathway; GO:0001819 positive regulation of cytokine production; GO:0044267 cellular protein metabolic process; GO:0048519 negative regulation of biological process; GO:0080134 regulation of response to stress; GO:0051239 regulation of multicellular organismal process; GO:0060341 regulation of cellular localization; GO:0042990 regulation of transcription factor import into nucleus; GO:0050688 regulation of defense response to virus; GO:0031349 positive regulation of defense response; GO:2000145 regulation of cell motility; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0051171 regulation of nitrogen compound metabolic process; GO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production; GO:1902680 positive regulation of RNA biosynthetic process; GO:0032880 regulation of protein localization; GO:0050778 positive regulation of immune response; GO:0002253 activation of immune response; GO:0051254 positive regulation of RNA metabolic process; GO:0006950 response to stress; GO:0032648 regulation of interferon-beta production; GO:0051270 regulation of cellular component movement; GO:0043900 regulation of multi-organism process; GO:0032675 regulation of interleukin-6 production; GO:0032101 regulation of response to external stimulus; GO:0030334 regulation of cell migration; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:1900182 positive regulation of protein localization to nucleus; GO:0032727 positive regulation of interferon-alpha production; GO:0046822 regulation of nucleocytoplasmic transport; GO:1904951 positive regulation of establishment of protein localization; GO:0031325 positive regulation of cellular metabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0048584 positive regulation of response to stimulus; GO:0006955 immune response; GO:0043412 macromolecule modification; GO:0002230 positive regulation of defense response to virus by host; GO:1903827 regulation of cellular protein localization; GO:1904591 positive regulation of protein import; GO:0070646 protein modification by small protein removal; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0001818 negative regulation of cytokine production; GO:0039528 cytoplasmic pattern recognition receptor signaling pathway in response to virus; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0042306 regulation of protein import into nucleus; GO:0007154 cell communication; GO:0045088 regulation of innate immune response; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0046824 positive regulation of nucleocytoplasmic transport; GO:0002221 pattern recognition receptor signaling pathway; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0050691 regulation of defense response to virus by host; GO:0002697 regulation of immune effector process; GO:0098586 cellular response to virus; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0043331 response to dsRNA; GO:0048522 positive regulation of cellular process; GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity; GO:0032386 regulation of intracellular transport; GO:0070647 protein modification by small protein conjugation or removal; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0051050 positive regulation of transport; GO:0009597 detection of virus; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0051607 defense response to virus; GO:1900180 regulation of protein localization to nucleus; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0006952 defense response; GO:0036211 protein modification process; GO:0051222 positive regulation of protein transport; GO:0009615 response to virus; GO:0032479 regulation of type I interferon production; GO:0002218 activation of innate immune response; GO:0002831 regulation of response to biotic stimulus; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0090316 positive regulation of intracellular protein transport; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:1903829 positive regulation of cellular protein localization; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0043207 response to external biotic stimulus; GO:1904589 regulation of protein import; GO:0050896 response to stimulus; GO:0016579 protein deubiquitination; GO:0051707 response to other organism; GO:0045087 innate immune response; GO:0070201 regulation of establishment of protein localization; GO:0071704 organic substance metabolic process; GO:0032757 positive regulation of interleukin-8 production; GO:0016032 viral process; GO:0034344 regulation of type III interferon production; GO:0002757 immune response-activating signal transduction; GO:0006508 proteolysis; GO:0033157 regulation of intracellular protein transport; GO:0009987 cellular process; GO:0042993 positive regulation of transcription factor import into nucleus; GO:0032755 positive regulation of interleukin-6 production; GO:0032645 regulation of granulocyte macrophage colony-stimulating factor production; GO:0045089 positive regulation of innate immune response; GO:0006355 regulation of transcription, DNA-templated; GO:0043330 response to exogenous dsRNA; GO:0035556 intracellular signal transduction; GO:0032388 positive regulation of intracellular transport; GO:0051049 regulation of transport; GO:0050792 regulation of viral process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0032728 positive regulation of interferon-beta production; GO:0002684 positive regulation of immune system process; GO:0001817 regulation of cytokine production; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0040012 regulation of locomotion; GO:0032480 negative regulation of type I interferon production; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0032587 ruffle membrane; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005911 cell-cell junction; GO:0005623 cell; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070160 occluding junction; GO:0098590 plasma membrane region; GO:0031256 leading edge membrane; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0031252 cell leading edge; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044463 cell projection part; GO:0005829 cytosol; GO:0005923 bicellular tight junction; GO:0015629 actin cytoskeleton; GO:0043296 apical junction complex; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0001726 ruffle; GO:0031253 cell projection membrane; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0031625 ubiquitin protein ligase binding; GO:0003690 double-stranded DNA binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0042802 identical protein binding; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003677 DNA binding; GO:0003723 RNA binding; GO:0005524 ATP binding; GO:0004386 helicase activity; GO:0003725 double-stranded RNA binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0008270 zinc ion binding; GO:0017111 nucleoside-triphosphatase activity; GO:0003727 single-stranded RNA binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0046914 transition metal ion binding; GO:0003676 nucleic acid binding; GO:0046872 metal ion binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0019899 enzyme binding; GO:0036094 small molecule binding; ","K12646","DDX58; ATP-dependent RNA helicase DDX58 [EC:3.6.3.14]","hsa05168 Herpes simplex infection - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); hsa05160 Hepatitis C - Homo sapiens (human); hsa04623 Cytosolic DNA-sensing pathway - Homo sapiens (human); hsa05162 Measles - Homo sapiens (human); hsa05161 Hepatitis B - Homo sapiens (human); hsa04622 RIG-I-like receptor signaling pathway - Homo sapiens (human); hsa05164 Influenza A - Homo sapiens (human); hsa04064 NF-kappa B signaling pathway - Homo sapiens (human); ","IPR031964; IPR011545; IPR021673; IPR014001; IPR027417; IPR011029; IPR001650; ","\"Caspase recruitment domain; DEAD/DEAH box helicase domain; C-terminal domain of RIG-I; Helicase superfamily 1/2, ATP-binding domain; P-loop containing nucleoside triphosphate hydrolase; Death-like domain; Helicase, C-terminal; \"\r"]
["O95793","Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1","STAU1",63.182,12.534,2.3,1,2,1,0.922,0.875,0.877,1.096,1.022,1.202,1.242,0.0127,"nucleus\r","GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:1900271 regulation of long-term synaptic potentiation; GO:0065008 regulation of biological quality; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0023051 regulation of signaling; GO:0050896 response to stimulus; GO:0042592 homeostatic process; GO:0010646 regulation of cell communication; GO:0006979 response to oxidative stress; GO:0034599 cellular response to oxidative stress; GO:0046726 positive regulation by virus of viral protein levels in host cell; GO:0045070 positive regulation of viral genome replication; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0070887 cellular response to chemical stimulus; GO:0048167 regulation of synaptic plasticity; GO:0051716 cellular response to stimulus; GO:1903902 positive regulation of viral life cycle; GO:0043902 positive regulation of multi-organism process; GO:0006950 response to stress; GO:0050804 modulation of synaptic transmission; GO:0043900 regulation of multi-organism process; GO:0050792 regulation of viral process; GO:0048522 positive regulation of cellular process; GO:0045069 regulation of viral genome replication; GO:0048518 positive regulation of biological process; GO:1900273 positive regulation of long-term synaptic potentiation; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0048524 positive regulation of viral process; GO:0046719 regulation by virus of viral protein levels in host cell; GO:1903900 regulation of viral life cycle; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0030425 dendrite; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0043025 neuronal cell body; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005856 cytoskeleton; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043229 intracellular organelle; GO:0010494 cytoplasmic stress granule; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005791 rough endoplasmic reticulum; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005875 microtubule associated complex; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0036477 somatodendritic compartment; GO:0035770 ribonucleoprotein granule; GO:0044297 cell body; GO:1990904 ribonucleoprotein complex; GO:0043234 protein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0019903 protein phosphatase binding; GO:0003725 double-stranded RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0019902 phosphatase binding; GO:0019899 enzyme binding; GO:0008157 protein phosphatase 1 binding; ","K17597",null,null,"IPR014720; IPR032478; ","\"Double-stranded RNA-binding domain; Staufen, C-terminal; \"\r"]
["O95810","Caveolae-associated protein 2 OS=Homo sapiens OX=9606 GN=CAVIN2","CAVIN2",47.173,69.869,25.9,10,14,10,1.183,1.109,1.153,0.878,0.884,0.818,0.749,0.000742,"cytoplasm\r",null,"GO:0016020 membrane; GO:0098857 membrane microdomain; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0005901 caveola; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005886 plasma membrane; GO:0044459 plasma membrane part; GO:0098590 plasma membrane region; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0044853 plasma membrane raft; GO:0098805 whole membrane; GO:0098589 membrane region; GO:0045121 membrane raft; GO:0044444 cytoplasmic part; ","GO:0072341 modified amino acid binding; GO:0005488 binding; GO:0019901 protein kinase binding; GO:0005543 phospholipid binding; GO:0043167 ion binding; GO:0008289 lipid binding; GO:0005080 protein kinase C binding; GO:0043168 anion binding; GO:0005515 protein binding; GO:0019900 kinase binding; GO:0001786 phosphatidylserine binding; GO:0019899 enzyme binding; "]
["O95816","BAG family molecular chaperone regulator 2 OS=Homo sapiens OX=9606 GN=BAG2","BAG2",23.772,20.053,25.1,5,7,5,1.225,1.239,1.202,0.778,0.785,0.807,0.646,3.27E-6,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0080134 regulation of response to stress; GO:0044238 primary metabolic process; GO:0071704 organic substance metabolic process; GO:0006457 protein folding; GO:0008152 metabolic process; GO:0050789 regulation of biological process; GO:0080135 regulation of cellular response to stress; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0065009 regulation of molecular function; GO:1900034 regulation of cellular response to heat; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009987 cellular process; GO:0065007 biological regulation; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0051087 chaperone binding; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0098772 molecular function regulator; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0042802 identical protein binding; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0030554 adenyl nucleotide binding; GO:0060590 ATPase regulator activity; GO:0000774 adenyl-nucleotide exchange factor activity; GO:0036094 small molecule binding; GO:0017076 purine nucleotide binding; ","K09556","BAG2; BCL2-associated athanogene 2","hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); ","IPR003103; ","BAG domain; \r"]
["O95817","BAG family molecular chaperone regulator 3 OS=Homo sapiens OX=9606 GN=BAG3","BAG3",61.594,27.67,11.1,6,12,6,0.954,0.925,0.953,1.098,1.066,1.081,1.146,0.000502,"nucleus\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0010941 regulation of cell death; GO:0007166 cell surface receptor signaling pathway; GO:1903533 regulation of protein targeting; GO:0007420 brain development; GO:0009605 response to external stimulus; GO:0009408 response to heat; GO:0032879 regulation of localization; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand; GO:0071214 cellular response to abiotic stimulus; GO:0080090 regulation of primary metabolic process; GO:0000122 negative regulation of transcription from RNA polymerase II promoter; GO:0044763 single-organism cellular process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0010660 regulation of muscle cell apoptotic process; GO:0080135 regulation of cellular response to stress; GO:0046825 regulation of protein export from nucleus; GO:0050790 regulation of catalytic activity; GO:0007417 central nervous system development; GO:0048583 regulation of response to stimulus; GO:0051223 regulation of protein transport; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0060548 negative regulation of cell death; GO:0042307 positive regulation of protein import into nucleus; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0033554 cellular response to stress; GO:0097191 extrinsic apoptotic signaling pathway; GO:0097190 apoptotic signaling pathway; GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors; GO:0009628 response to abiotic stimulus; GO:0043067 regulation of programmed cell death; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0042990 regulation of transcription factor import into nucleus; GO:0060341 regulation of cellular localization; GO:0045892 negative regulation of transcription, DNA-templated; GO:0009889 regulation of biosynthetic process; GO:0043620 regulation of DNA-templated transcription in response to stress; GO:0051171 regulation of nitrogen compound metabolic process; GO:0032880 regulation of protein localization; GO:0007275 multicellular organism development; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0006950 response to stress; GO:0048731 system development; GO:0071496 cellular response to external stimulus; GO:0009892 negative regulation of metabolic process; GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress; GO:1900182 positive regulation of protein localization to nucleus; GO:0009890 negative regulation of biosynthetic process; GO:0046822 regulation of nucleocytoplasmic transport; GO:1904951 positive regulation of establishment of protein localization; GO:0031647 regulation of protein stability; GO:0012501 programmed cell death; GO:1904591 positive regulation of protein import; GO:0050821 protein stabilization; GO:1903827 regulation of cellular protein localization; GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress; GO:0044699 single-organism process; GO:0051253 negative regulation of RNA metabolic process; GO:0006457 protein folding; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0042306 regulation of protein import into nucleus; GO:0007154 cell communication; GO:0006915 apoptotic process; GO:0046824 positive regulation of nucleocytoplasmic transport; GO:0060322 head development; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0021510 spinal cord development; GO:0031326 regulation of cellular biosynthetic process; GO:0032386 regulation of intracellular transport; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051050 positive regulation of transport; GO:0050789 regulation of biological process; GO:0034605 cellular response to heat; GO:1902679 negative regulation of RNA biosynthetic process; GO:1900180 regulation of protein localization to nucleus; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:1900034 regulation of cellular response to heat; GO:0048856 anatomical structure development; GO:0051222 positive regulation of protein transport; GO:0038034 signal transduction in absence of ligand; GO:0071260 cellular response to mechanical stimulus; GO:0043069 negative regulation of programmed cell death; GO:0090316 positive regulation of intracellular protein transport; GO:0060255 regulation of macromolecule metabolic process; GO:1903829 positive regulation of cellular protein localization; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:1904589 regulation of protein import; GO:0050896 response to stimulus; GO:0070201 regulation of establishment of protein localization; GO:0009612 response to mechanical stimulus; GO:0043066 negative regulation of apoptotic process; GO:0009266 response to temperature stimulus; GO:0009987 cellular process; GO:0033157 regulation of intracellular protein transport; GO:0042993 positive regulation of transcription factor import into nucleus; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0032388 positive regulation of intracellular transport; GO:0051049 regulation of transport; GO:0010664 negative regulation of striated muscle cell apoptotic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0010656 negative regulation of muscle cell apoptotic process; GO:0046827 positive regulation of protein export from nucleus; GO:0010662 regulation of striated muscle cell apoptotic process; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0071944 cell periphery; GO:0030016 myofibril; GO:0005737 cytoplasm; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0030018 Z disc; GO:0005829 cytosol; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0031674 I band; GO:0044422 organelle part; GO:0005886 plasma membrane; GO:0099081 supramolecular polymer; GO:0043228 non-membrane-bounded organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:0043292 contractile fiber; GO:0030017 sarcomere; GO:0043005 neuron projection; GO:0044449 contractile fiber part; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0051087 chaperone binding; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0044877 macromolecular complex binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0098772 molecular function regulator; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0050839 cell adhesion molecule binding; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0045296 cadherin binding; GO:0030554 adenyl nucleotide binding; GO:0060590 ATPase regulator activity; GO:0000774 adenyl-nucleotide exchange factor activity; GO:0032403 protein complex binding; GO:0036094 small molecule binding; GO:0017076 purine nucleotide binding; ","K09557",null,null,"IPR003103; IPR001202; ","BAG domain; WW domain; \r"]
["O95831","Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1","AIFM1",66.9,58.6,20.7,10,18,10,1.058,1.067,1.065,0.932,0.924,0.955,0.881,2.42E-4,"mitochondria\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0010941 regulation of cell death; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0070997 neuron death; GO:0043523 regulation of neuron apoptotic process; GO:0071384 cellular response to corticosteroid stimulus; GO:0051385 response to mineralocorticoid; GO:1904045 cellular response to aldosterone; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0065003 macromolecular complex assembly; GO:0044093 positive regulation of molecular function; GO:0048545 response to steroid hormone; GO:0009719 response to endogenous stimulus; GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0007399 nervous system development; GO:0052548 regulation of endopeptidase activity; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0010950 positive regulation of endopeptidase activity; GO:0080090 regulation of primary metabolic process; GO:0010257 NADH dehydrogenase complex assembly; GO:0048699 generation of neurons; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0000302 response to reactive oxygen species; GO:0044763 single-organism cellular process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0071396 cellular response to lipid; GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0043525 positive regulation of neuron apoptotic process; GO:0010243 response to organonitrogen compound; GO:0071731 response to nitric oxide; GO:0051336 regulation of hydrolase activity; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:1901698 response to nitrogen compound; GO:0010604 positive regulation of macromolecule metabolic process; GO:0010952 positive regulation of peptidase activity; GO:0043068 positive regulation of programmed cell death; GO:0071392 cellular response to estradiol stimulus; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0033554 cellular response to stress; GO:0097190 apoptotic signaling pathway; GO:2001056 positive regulation of cysteine-type endopeptidase activity; GO:0034976 response to endoplasmic reticulum stress; GO:0009628 response to abiotic stimulus; GO:0045454 cell redox homeostasis; GO:0043067 regulation of programmed cell death; GO:1901700 response to oxygen-containing compound; GO:0032355 response to estradiol; GO:0032981 mitochondrial respiratory chain complex I assembly; GO:0030261 chromosome condensation; GO:0006323 DNA packaging; GO:0051345 positive regulation of hydrolase activity; GO:0070482 response to oxygen levels; GO:0051171 regulation of nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0006461 protein complex assembly; GO:1901655 cellular response to ketone; GO:0006950 response to stress; GO:0048731 system development; GO:1902510 regulation of apoptotic DNA fragmentation; GO:0071496 cellular response to external stimulus; GO:0071407 cellular response to organic cyclic compound; GO:0030162 regulation of proteolysis; GO:0010033 response to organic substance; GO:0031668 cellular response to extracellular stimulus; GO:0030182 neuron differentiation; GO:0051247 positive regulation of protein metabolic process; GO:0090649 response to oxygen-glucose deprivation; GO:0051276 chromosome organization; GO:0042542 response to hydrogen peroxide; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0012501 programmed cell death; GO:0036293 response to decreased oxygen levels; GO:0001101 response to acid chemical; GO:0048869 cellular developmental process; GO:1904044 response to aldosterone; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0071383 cellular response to steroid hormone stimulus; GO:0002931 response to ischemia; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0009893 positive regulation of metabolic process; GO:0007005 mitochondrion organization; GO:0006915 apoptotic process; GO:0006979 response to oxidative stress; GO:0034599 cellular response to oxidative stress; GO:0010035 response to inorganic substance; GO:0070887 cellular response to chemical stimulus; GO:0071103 DNA conformation change; GO:0032502 developmental process; GO:0043200 response to amino acid; GO:0051402 neuron apoptotic process; GO:0034614 cellular response to reactive oxygen species; GO:0071822 protein complex subunit organization; GO:2000116 regulation of cysteine-type endopeptidase activity; GO:1900117 regulation of execution phase of apoptosis; GO:0055114 oxidation-reduction process; GO:0009636 response to toxic substance; GO:0048522 positive regulation of cellular process; GO:0019725 cellular homeostasis; GO:0023052 signaling; GO:0010942 positive regulation of cell death; GO:0071732 cellular response to nitric oxide; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0097031 mitochondrial respiratory chain complex I biogenesis; GO:0032268 regulation of cellular protein metabolic process; GO:0051052 regulation of DNA metabolic process; GO:1902065 response to L-glutamate; GO:1901699 cellular response to nitrogen compound; GO:0032870 cellular response to hormone stimulus; GO:0071241 cellular response to inorganic substance; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0070271 protein complex biogenesis; GO:0052547 regulation of peptidase activity; GO:0048856 anatomical structure development; GO:0033108 mitochondrial respiratory chain complex assembly; GO:0016043 cellular component organization; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0071310 cellular response to organic substance; GO:0043065 positive regulation of apoptotic process; GO:0050896 response to stimulus; GO:0097193 intrinsic apoptotic signaling pathway; GO:0031669 cellular response to nutrient levels; GO:0070301 cellular response to hydrogen peroxide; GO:0033993 response to lipid; GO:0042592 homeostatic process; GO:0090650 cellular response to oxygen-glucose deprivation; GO:0009991 response to extracellular stimulus; GO:0030154 cell differentiation; GO:0045862 positive regulation of proteolysis; GO:1901216 positive regulation of neuron death; GO:0031960 response to corticosteroid; GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0071453 cellular response to oxygen levels; GO:0071389 cellular response to mineralocorticoid stimulus; GO:0009987 cellular process; GO:1901214 regulation of neuron death; GO:0043623 cellular protein complex assembly; GO:0034622 cellular macromolecular complex assembly; GO:0035556 intracellular signal transduction; GO:0048518 positive regulation of biological process; GO:0043933 macromolecular complex subunit organization; GO:0043085 positive regulation of catalytic activity; GO:1901701 cellular response to oxygen-containing compound; GO:1903624 regulation of DNA catabolic process; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0071495 cellular response to endogenous stimulus; GO:0051246 regulation of protein metabolic process; GO:1902170 cellular response to reactive nitrogen species; GO:0051128 regulation of cellular component organization; GO:0031667 response to nutrient levels; GO:0009725 response to hormone; GO:0042981 regulation of apoptotic process; GO:0036294 cellular response to decreased oxygen levels; GO:1901654 response to ketone; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044429 mitochondrial part; GO:0031090 organelle membrane; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005740 mitochondrial envelope; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0031970 organelle envelope lumen; GO:0005758 mitochondrial intermembrane space; GO:0005622 intracellular; GO:0044464 cell part; GO:0031975 envelope; GO:0019866 organelle inner membrane; GO:0048471 perinuclear region of cytoplasm; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0031966 mitochondrial membrane; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; ","GO:0016174 NAD(P)H oxidase activity; GO:0003677 DNA binding; GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:1901265 nucleoside phosphate binding; GO:0050660 flavin adenine dinucleotide binding; GO:0046983 protein dimerization activity; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0048037 cofactor binding; GO:0071949 FAD binding; GO:0016491 oxidoreductase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0043168 anion binding; GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor; GO:0050662 coenzyme binding; GO:0036094 small molecule binding; ","K04727","PDCD8; programmed cell death 8 (apoptosis-inducing factor) [EC:1.-.-.-]","hsa04210 Apoptosis - Homo sapiens (human); hsa04217 Necroptosis - Homo sapiens (human); ","IPR016156; IPR029324; IPR004099; IPR023753; ","\"FAD/NAD-linked reductase, dimerisation domain; Mitochondrial apoptosis-inducing factor, C-terminal domain; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; FAD/NAD(P)-binding domain; \"\r"]
["O95832","Claudin-1 OS=Homo sapiens OX=9606 GN=CLDN1","CLDN1",22.744,2.6552,8.5,2,2,2,0.968,1.054,0.924,0.997,0.991,1.074,1.039,0.443,"plasma membrane\r","GO:0044409 entry into host; GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0048732 gland development; GO:0071345 cellular response to cytokine stimulus; GO:0009607 response to biotic stimulus; GO:0022610 biological adhesion; GO:0009605 response to external stimulus; GO:0065003 macromolecular complex assembly; GO:0048545 response to steroid hormone; GO:0007155 cell adhesion; GO:0009719 response to endogenous stimulus; GO:0070848 response to growth factor; GO:0044419 interspecies interaction between organisms; GO:0007422 peripheral nervous system development; GO:0044765 single-organism transport; GO:0046718 viral entry into host cell; GO:0007399 nervous system development; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0043588 skin development; GO:0002064 epithelial cell development; GO:2000810 regulation of bicellular tight junction assembly; GO:0071398 cellular response to fatty acid; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:1901888 regulation of cell junction assembly; GO:0071559 response to transforming growth factor beta; GO:0032501 multicellular organismal process; GO:0071396 cellular response to lipid; GO:0051704 multi-organism process; GO:0006810 transport; GO:0051291 protein heterooligomerization; GO:0048513 animal organ development; GO:0030104 water homeostasis; GO:0030855 epithelial cell differentiation; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:1903544 response to butyrate; GO:0051260 protein homooligomerization; GO:0009628 response to abiotic stimulus; GO:0051806 entry into cell of other organism involved in symbiotic interaction; GO:1901700 response to oxygen-containing compound; GO:0051259 protein oligomerization; GO:0042493 response to drug; GO:1902578 single-organism localization; GO:0071229 cellular response to acid chemical; GO:0061008 hepaticobiliary system development; GO:0061436 establishment of skin barrier; GO:0007275 multicellular organism development; GO:0070542 response to fatty acid; GO:0009617 response to bacterium; GO:0048878 chemical homeostasis; GO:0006461 protein complex assembly; GO:0043297 apical junction assembly; GO:0006950 response to stress; GO:0032496 response to lipopolysaccharide; GO:0048731 system development; GO:0097305 response to alcohol; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0003158 endothelium development; GO:0090557 establishment of endothelial intestinal barrier; GO:0001889 liver development; GO:0050891 multicellular organismal water homeostasis; GO:0001885 endothelial cell development; GO:0071284 cellular response to lead ion; GO:0015893 drug transport; GO:0061772 drug transport across blood-nerve barrier; GO:0051179 localization; GO:0071248 cellular response to metal ion; GO:0006955 immune response; GO:0031100 animal organ regeneration; GO:0001101 response to acid chemical; GO:0048869 cellular developmental process; GO:0071560 cellular response to transforming growth factor beta stimulus; GO:0071346 cellular response to interferon-gamma; GO:0045216 cell-cell junction organization; GO:0044699 single-organism process; GO:0071363 cellular response to growth factor stimulus; GO:0044764 multi-organism cellular process; GO:0045446 endothelial cell differentiation; GO:0048871 multicellular organismal homeostasis; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0022607 cellular component assembly; GO:0010035 response to inorganic substance; GO:0034612 response to tumor necrosis factor; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0006970 response to osmotic stress; GO:0009888 tissue development; GO:0071822 protein complex subunit organization; GO:0034097 response to cytokine; GO:0002237 response to molecule of bacterial origin; GO:0009636 response to toxic substance; GO:0098609 cell-cell adhesion; GO:0048522 positive regulation of cellular process; GO:1901890 positive regulation of cell junction assembly; GO:0009651 response to salt stress; GO:0010038 response to metal ion; GO:0051384 response to glucocorticoid; GO:0030260 entry into host cell; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0007568 aging; GO:0051828 entry into other organism involved in symbiotic interaction; GO:1903348 positive regulation of bicellular tight junction assembly; GO:0071241 cellular response to inorganic substance; GO:0010288 response to lead ion; GO:0006952 defense response; GO:0070271 protein complex biogenesis; GO:0048856 anatomical structure development; GO:0016043 cellular component organization; GO:0034329 cell junction assembly; GO:0008065 establishment of blood-nerve barrier; GO:0097421 liver regeneration; GO:0071356 cellular response to tumor necrosis factor; GO:0045471 response to ethanol; GO:0071310 cellular response to organic substance; GO:0019058 viral life cycle; GO:0044087 regulation of cellular component biogenesis; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0048468 cell development; GO:0045087 innate immune response; GO:0042592 homeostatic process; GO:0033993 response to lipid; GO:0030154 cell differentiation; GO:0016032 viral process; GO:0031960 response to corticosteroid; GO:0070830 bicellular tight junction assembly; GO:0061028 establishment of endothelial barrier; GO:0009987 cellular process; GO:1903545 cellular response to butyrate; GO:0007043 cell-cell junction assembly; GO:0050878 regulation of body fluid levels; GO:0006972 hyperosmotic response; GO:0070673 response to interleukin-18; GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules; GO:0034341 response to interferon-gamma; GO:0051701 interaction with host; GO:0048518 positive regulation of biological process; GO:0043933 macromolecular complex subunit organization; GO:0071548 response to dexamethasone; GO:1901701 cellular response to oxygen-containing compound; GO:0034330 cell junction organization; GO:0042538 hyperosmotic salinity response; GO:0071495 cellular response to endogenous stimulus; GO:0044767 single-organism developmental process; GO:0051128 regulation of cellular component organization; GO:0033561 regulation of water loss via skin; GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules; GO:0031099 regeneration; GO:0009725 response to hormone; GO:0044089 positive regulation of cellular component biogenesis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:1901654 response to ketone; ","GO:0016020 membrane; GO:0031226 intrinsic component of plasma membrane; GO:0016324 apical plasma membrane; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005911 cell-cell junction; GO:0005623 cell; GO:0005923 bicellular tight junction; GO:0016021 integral component of membrane; GO:0016328 lateral plasma membrane; GO:0043296 apical junction complex; GO:0005886 plasma membrane; GO:0070160 occluding junction; GO:0044459 plasma membrane part; GO:0098590 plasma membrane region; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0045177 apical part of cell; ","GO:0060089 molecular transducer activity; GO:0005515 protein binding; GO:0004872 receptor activity; GO:0042802 identical protein binding; GO:0005198 structural molecule activity; GO:0001618 virus receptor activity; GO:0005488 binding; ","K06087","CLDN; claudin","hsa04670 Leukocyte transendothelial migration - Homo sapiens (human); hsa04530 Tight junction - Homo sapiens (human); hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human); hsa05160 Hepatitis C - Homo sapiens (human); hsa04514 Cell adhesion molecules (CAMs) - Homo sapiens (human); "]
["O95833","Chloride intracellular channel protein 3 OS=Homo sapiens OX=9606 GN=CLIC3","CLIC3",26.648,41.987,34.3,6,7,6,0.874,0.976,1.029,1.111,0.998,1.016,1.085,0.228,"plasma membrane\r","GO:0098661 inorganic anion transmembrane transport; GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0051716 cellular response to stimulus; GO:0034220 ion transmembrane transport; GO:0098660 inorganic ion transmembrane transport; GO:0051049 regulation of transport; GO:0043269 regulation of ion transport; GO:0044699 single-organism process; GO:0006821 chloride transport; GO:0023052 signaling; GO:0050896 response to stimulus; GO:0098656 anion transmembrane transport; GO:1902476 chloride transmembrane transport; GO:0051234 establishment of localization; GO:0006820 anion transport; GO:0006810 transport; GO:0034762 regulation of transmembrane transport; GO:0055085 transmembrane transport; GO:0007165 signal transduction; GO:0050789 regulation of biological process; GO:0034765 regulation of ion transmembrane transport; GO:0007154 cell communication; GO:0006811 ion transport; GO:0032879 regulation of localization; GO:0051179 localization; GO:0009987 cellular process; GO:0015698 inorganic anion transport; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0034702 ion channel complex; GO:1990351 transporter complex; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:1902495 transmembrane transporter complex; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0034707 chloride channel complex; GO:0043230 extracellular organelle; GO:0044428 nuclear part; ","GO:0015075 ion transmembrane transporter activity; GO:0022803 passive transmembrane transporter activity; GO:0005253 anion channel activity; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0005254 chloride channel activity; GO:0015103 inorganic anion transmembrane transporter activity; GO:0015267 channel activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0015108 chloride transmembrane transporter activity; GO:0005244 voltage-gated ion channel activity; GO:0022838 substrate-specific channel activity; GO:0005488 binding; GO:0005216 ion channel activity; GO:0022836 gated channel activity; GO:0022832 voltage-gated channel activity; GO:0008509 anion transmembrane transporter activity; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; ","K05023",null,null,"IPR010987; IPR004045; IPR012336; ","\"Glutathione S-transferase, C-terminal-like; Glutathione S-transferase, N-terminal; Thioredoxin-like fold; \"\r"]
["O95834","Echinoderm microtubule-associated protein-like 2 OS=Homo sapiens OX=9606 GN=EML2","EML2",70.678,60.486,18.8,11,16,11,1.014,1.099,1.147,0.913,0.926,0.926,0.848,0.0463,"plasma membrane\r","GO:0050794 regulation of cellular process; GO:0031111 negative regulation of microtubule polymerization or depolymerization; GO:0007601 visual perception; GO:0051129 negative regulation of cellular component organization; GO:0044087 regulation of cellular component biogenesis; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0031110 regulation of microtubule polymerization or depolymerization; GO:0050877 neurological system process; GO:0031115 negative regulation of microtubule polymerization; GO:0032271 regulation of protein polymerization; GO:0051493 regulation of cytoskeleton organization; GO:0031333 negative regulation of protein complex assembly; GO:0070507 regulation of microtubule cytoskeleton organization; GO:0007600 sensory perception; GO:0003008 system process; GO:0051494 negative regulation of cytoskeleton organization; GO:0033043 regulation of organelle organization; GO:0031113 regulation of microtubule polymerization; GO:0050953 sensory perception of light stimulus; GO:0032501 multicellular organismal process; GO:0032886 regulation of microtubule-based process; GO:0010639 negative regulation of organelle organization; GO:0043254 regulation of protein complex assembly; GO:0050789 regulation of biological process; GO:1902904 negative regulation of supramolecular fiber organization; GO:0010968 regulation of microtubule nucleation; GO:0051128 regulation of cellular component organization; GO:0007605 sensory perception of sound; GO:0032272 negative regulation of protein polymerization; GO:0065007 biological regulation; GO:1902903 regulation of supramolecular fiber organization; GO:0050954 sensory perception of mechanical stimulus; ","GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0005874 microtubule; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0005875 microtubule associated complex; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0005819 spindle; GO:0044422 organelle part; GO:0099081 supramolecular polymer; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0005856 cytoskeleton; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0043234 protein complex; ","GO:0008092 cytoskeletal protein binding; GO:0005102 receptor binding; GO:0008017 microtubule binding; GO:0005488 binding; GO:0015631 tubulin binding; GO:0005515 protein binding; GO:0008022 protein C-terminus binding; ","K18595",null,null,"IPR005108; IPR017986; IPR015943; IPR011047; ","HELP; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain; Quinoprotein alcohol dehydrogenase-like superfamily; \r"]
["O95861","3'(2'),5'-bisphosphate nucleotidase 1 OS=Homo sapiens OX=9606 GN=BPNT1","BPNT1",33.392,21.359,22.7,8,13,8,1.082,0.989,1.049,0.943,1.053,0.915,0.933,0.233,"mitochondria\r","GO:0016310 phosphorylation; GO:0044707 single-multicellular organism process; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0046486 glycerolipid metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0009259 ribonucleotide metabolic process; GO:0009117 nucleotide metabolic process; GO:0046854 phosphatidylinositol phosphorylation; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0034032 purine nucleoside bisphosphate metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0030258 lipid modification; GO:0019693 ribose phosphate metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0006650 glycerophospholipid metabolic process; GO:0046488 phosphatidylinositol metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009119 ribonucleoside metabolic process; GO:0009987 cellular process; GO:0006629 lipid metabolic process; GO:0006790 sulfur compound metabolic process; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0033865 nucleoside bisphosphate metabolic process; GO:0048731 system development; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0033875 ribonucleoside bisphosphate metabolic process; GO:0072521 purine-containing compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:0016311 dephosphorylation; GO:0032501 multicellular organismal process; GO:0006163 purine nucleotide metabolic process; GO:0046834 lipid phosphorylation; GO:0046128 purine ribonucleoside metabolic process; GO:0006793 phosphorus metabolic process; GO:0034035 purine ribonucleoside bisphosphate metabolic process; GO:0044767 single-organism developmental process; GO:0044710 single-organism metabolic process; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0006644 phospholipid metabolic process; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:0043436 oxoacid metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0003824 catalytic activity; GO:0042578 phosphoric ester hydrolase activity; GO:0005488 binding; GO:0016791 phosphatase activity; GO:0008252 nucleotidase activity; GO:0043167 ion binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0046872 metal ion binding; GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity; GO:0043169 cation binding; GO:0016787 hydrolase activity; ","K01082","cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]","hsa00920 Sulfur metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); "]
["O95864","Fatty acid desaturase 2 OS=Homo sapiens OX=9606 GN=FADS2","FADS2",52.259,34.559,19.1,8,14,8,1.339,1.32,1.364,0.603,0.648,0.673,0.478,2.26E-5,"plasma membrane\r","GO:0033559 unsaturated fatty acid metabolic process; GO:0016053 organic acid biosynthetic process; GO:0036109 alpha-linolenic acid metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0008610 lipid biosynthetic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0009987 cellular process; GO:0006629 lipid metabolic process; GO:0044711 single-organism biosynthetic process; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0043651 linoleic acid metabolic process; GO:0044763 single-organism cellular process; GO:0006636 unsaturated fatty acid biosynthetic process; GO:0006631 fatty acid metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0006633 fatty acid biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0046394 carboxylic acid biosynthetic process; GO:0001676 long-chain fatty acid metabolic process; GO:0044710 single-organism metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0044283 small molecule biosynthetic process; GO:0006082 organic acid metabolic process; GO:0072330 monocarboxylic acid biosynthetic process; GO:0043436 oxoacid metabolic process; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0031226 intrinsic component of plasma membrane; GO:0005783 endoplasmic reticulum; GO:0071944 cell periphery; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0044432 endoplasmic reticulum part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; ","GO:0016213 linoleoyl-CoA desaturase activity; GO:0004768 stearoyl-CoA 9-desaturase activity; GO:0003824 catalytic activity; GO:0016215 acyl-CoA desaturase activity; GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water; GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; GO:0016491 oxidoreductase activity; ","K10226","FADS2; acyl-CoA 6-desaturase (Delta-6 desaturase) [EC:1.14.19.3]","hsa03320 PPAR signaling pathway - Homo sapiens (human); hsa01040 Biosynthesis of unsaturated fatty acids - Homo sapiens (human); hsa01212 Fatty acid metabolism - Homo sapiens (human); hsa00592 alpha-Linolenic acid metabolism - Homo sapiens (human); ","IPR005804; IPR001199; ","Fatty acid desaturase domain; Cytochrome b5-like heme/steroid binding domain; \r"]
["O95865","N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 OS=Homo sapiens OX=9606 GN=DDAH2","DDAH2",29.644,74.011,46.7,12,22,11,1.106,1.135,1.112,0.837,0.934,0.849,0.781,0.00218,"cyto_nucl\r","GO:0044700 single organism signaling; GO:1901606 alpha-amino acid catabolic process; GO:0010941 regulation of cell death; GO:0045428 regulation of nitric oxide biosynthetic process; GO:0009891 positive regulation of biosynthetic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0006520 cellular amino acid metabolic process; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0045429 positive regulation of nitric oxide biosynthetic process; GO:0051716 cellular response to stimulus; GO:0031326 regulation of cellular biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006525 arginine metabolic process; GO:0048522 positive regulation of cellular process; GO:0019932 second-messenger-mediated signaling; GO:0031323 regulation of cellular metabolic process; GO:0023052 signaling; GO:0051341 regulation of oxidoreductase activity; GO:0046395 carboxylic acid catabolic process; GO:1901575 organic substance catabolic process; GO:0050789 regulation of biological process; GO:0032768 regulation of monooxygenase activity; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0009065 glutamine family amino acid catabolic process; GO:1904407 positive regulation of nitric oxide metabolic process; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0009063 cellular amino acid catabolic process; GO:0006082 organic acid metabolic process; GO:2000377 regulation of reactive oxygen species metabolic process; GO:0050999 regulation of nitric-oxide synthase activity; GO:0060548 negative regulation of cell death; GO:0000052 citrulline metabolic process; GO:0043436 oxoacid metabolic process; GO:0050794 regulation of cellular process; GO:0043069 negative regulation of programmed cell death; GO:1903428 positive regulation of reactive oxygen species biosynthetic process; GO:0007263 nitric oxide mediated signal transduction; GO:0043067 regulation of programmed cell death; GO:0046209 nitric oxide metabolic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0072593 reactive oxygen species metabolic process; GO:0043066 negative regulation of apoptotic process; GO:0009889 regulation of biosynthetic process; GO:0044248 cellular catabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:2001057 reactive nitrogen species metabolic process; GO:0009987 cellular process; GO:0009064 glutamine family amino acid metabolic process; GO:1903409 reactive oxygen species biosynthetic process; GO:0035556 intracellular signal transduction; GO:0044712 single-organism catabolic process; GO:1903426 regulation of reactive oxygen species biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0044282 small molecule catabolic process; GO:1901605 alpha-amino acid metabolic process; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:2000379 positive regulation of reactive oxygen species metabolic process; GO:1901565 organonitrogen compound catabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0031325 positive regulation of cellular metabolic process; GO:0016054 organic acid catabolic process; GO:0019752 carboxylic acid metabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0009056 catabolic process; GO:0006809 nitric oxide biosynthetic process; GO:0042981 regulation of apoptotic process; GO:0006527 arginine catabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005815 microtubule organizing center; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016597 amino acid binding; GO:0031406 carboxylic acid binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines; GO:0043167 ion binding; GO:0043177 organic acid binding; GO:0016403 dimethylargininase activity; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0043168 anion binding; GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; GO:0036094 small molecule binding; ","K01482"]
["O95867","Lymphocyte antigen 6 complex locus protein G6c OS=Homo sapiens OX=9606 GN=LY6G6C","LY6G6C",13.821,24.918,22.4,3,3,3,0.79,1.007,0.89,1.159,1.051,1.103,1.233,0.0475,"extracellular\r","GO:0043687 post-translational protein modification; GO:0006501 C-terminal protein lipidation; GO:0044267 cellular protein metabolic process; GO:0009058 biosynthetic process; GO:0018410 C-terminal protein amino acid modification; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044237 cellular metabolic process; GO:0044249 cellular biosynthetic process; GO:0042157 lipoprotein metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0006497 protein lipidation; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:0009987 cellular process; GO:0042158 lipoprotein biosynthetic process; ","GO:0016020 membrane; GO:0044464 cell part; GO:0071944 cell periphery; GO:0044425 membrane part; GO:0031225 anchored component of membrane; GO:0031224 intrinsic component of membrane; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; ",null,"K06846"]
["O95881","Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12","TXNDC12",19.206,28.34,27.9,4,7,4,0.742,0.844,0.961,1.094,1.153,1.188,1.349,0.0179,"extracellular\r","GO:0050794 regulation of cellular process; GO:0010941 regulation of cell death; GO:0065008 regulation of biological quality; GO:0043069 negative regulation of programmed cell death; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0045454 cell redox homeostasis; GO:0048869 cellular developmental process; GO:0043067 regulation of programmed cell death; GO:0044699 single-organism process; GO:0080134 regulation of response to stress; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:1905897 regulation of response to endoplasmic reticulum stress; GO:2001233 regulation of apoptotic signaling pathway; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:0008152 metabolic process; GO:0010646 regulation of cell communication; GO:0023057 negative regulation of signaling; GO:2001243 negative regulation of intrinsic apoptotic signaling pathway; GO:0010648 negative regulation of cell communication; GO:0043066 negative regulation of apoptotic process; GO:1902235 regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway; GO:0032502 developmental process; GO:1902531 regulation of intracellular signal transduction; GO:0055114 oxidation-reduction process; GO:0044763 single-organism cellular process; GO:0019725 cellular homeostasis; GO:0048585 negative regulation of response to stimulus; GO:1903573 negative regulation of response to endoplasmic reticulum stress; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0050789 regulation of biological process; GO:1902532 negative regulation of intracellular signal transduction; GO:0080135 regulation of cellular response to stress; GO:0044710 single-organism metabolic process; GO:0044767 single-organism developmental process; GO:0048583 regulation of response to stimulus; GO:2001242 regulation of intrinsic apoptotic signaling pathway; GO:0060548 negative regulation of cell death; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0005788 endoplasmic reticulum lumen; GO:0043229 intracellular organelle; GO:0005783 endoplasmic reticulum; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044432 endoplasmic reticulum part; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0015036 disulfide oxidoreductase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016667 oxidoreductase activity, acting on a sulfur group of donors; GO:0005515 protein binding; GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor; GO:0019153 protein-disulfide reductase (glutathione) activity; GO:0015037 peptide disulfide oxidoreductase activity; GO:0016491 oxidoreductase activity; ","K05360","TXNDC12; protein-disulfide reductase (glutathione) [EC:1.8.4.2]","hsa00480 Glutathione metabolism - Homo sapiens (human); ","IPR013766; IPR012336; ","Thioredoxin domain; Thioredoxin-like fold; \r"]
["O95965","Integrin beta-like protein 1 OS=Homo sapiens OX=9606 GN=ITGBL1","ITGBL1",53.921,12.694,9.7,3,3,3,1.04,1.289,1.017,0.939,0.887,0.858,0.802,0.0546,"extracellular\r","GO:0007155 cell adhesion; GO:0022610 biological adhesion; ","GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005576 extracellular region; ","GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR013111; IPR000742; ","\"EGF-like domain, extracellular; EGF-like domain; \"\r"]
["O95967","EGF-containing fibulin-like extracellular matrix protein 2 OS=Homo sapiens OX=9606 GN=EFEMP2","EFEMP2",49.405,26.739,11.5,4,7,4,1.159,1.213,1.131,0.819,0.816,0.821,0.701,0.00336,"extracellular\r",null,"GO:0031012 extracellular matrix; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0005578 proteinaceous extracellular matrix; GO:0043227 membrane-bounded organelle; GO:0044420 extracellular matrix component; GO:0005576 extracellular region; GO:0043230 extracellular organelle; GO:0005604 basement membrane; ","GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005201 extracellular matrix structural constituent; GO:0005515 protein binding; GO:0005509 calcium ion binding; GO:0005198 structural molecule activity; GO:0005488 binding; GO:0043167 ion binding; ","K19866",null,null,"IPR026823; IPR001881; IPR000742; IPR009030; ","Complement Clr-like EGF domain; EGF-like calcium-binding domain; EGF-like domain; Growth factor receptor cysteine-rich domain; \r"]
["O95980","Reversion-inducing cysteine-rich protein with Kazal motifs OS=Homo sapiens OX=9606 GN=RECK","RECK",106.46,25.308,7.6,6,6,6,1.175,1.124,1.168,0.856,0.859,0.925,0.761,0.000698,"extracellular\r","GO:0021700 developmental maturation; GO:0001568 blood vessel development; GO:0022414 reproductive process; GO:0007566 embryo implantation; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0042157 lipoprotein metabolic process; GO:0040013 negative regulation of locomotion; GO:0010466 negative regulation of peptidase activity; GO:0008152 metabolic process; GO:0035107 appendage morphogenesis; GO:0032879 regulation of localization; GO:0044706 multi-multicellular organism process; GO:0044702 single organism reproductive process; GO:0060173 limb development; GO:0030198 extracellular matrix organization; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009790 embryo development; GO:0042158 lipoprotein biosynthetic process; GO:0035113 embryonic appendage morphogenesis; GO:0048598 embryonic morphogenesis; GO:0052548 regulation of endopeptidase activity; GO:0032502 developmental process; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0001944 vasculature development; GO:2000146 negative regulation of cell motility; GO:0031323 regulation of cellular metabolic process; GO:0043086 negative regulation of catalytic activity; GO:0010605 negative regulation of macromolecule metabolic process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:1904684 negative regulation of metalloendopeptidase activity; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0051336 regulation of hydrolase activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0035115 embryonic forelimb morphogenesis; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0006497 protein lipidation; GO:0006464 cellular protein modification process; GO:0052547 regulation of peptidase activity; GO:0036211 protein modification process; GO:1905048 regulation of metallopeptidase activity; GO:0048856 anatomical structure development; GO:0071695 anatomical structure maturation; GO:0051271 negative regulation of cellular component movement; GO:0072359 circulatory system development; GO:0043687 post-translational protein modification; GO:0000003 reproduction; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0010951 negative regulation of endopeptidase activity; GO:0060255 regulation of macromolecule metabolic process; GO:0044267 cellular protein metabolic process; GO:1905049 negative regulation of metallopeptidase activity; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0051346 negative regulation of hydrolase activity; GO:0071704 organic substance metabolic process; GO:0009653 anatomical structure morphogenesis; GO:0007565 female pregnancy; GO:0043062 extracellular structure organization; GO:2000145 regulation of cell motility; GO:0007275 multicellular organism development; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:1904683 regulation of metalloendopeptidase activity; GO:0006501 C-terminal protein lipidation; GO:0045861 negative regulation of proteolysis; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0072358 cardiovascular system development; GO:0030334 regulation of cell migration; GO:0030162 regulation of proteolysis; GO:0018410 C-terminal protein amino acid modification; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0044249 cellular biosynthetic process; GO:0048736 appendage development; GO:0034645 cellular macromolecule biosynthetic process; GO:0030336 negative regulation of cell migration; GO:0030326 embryonic limb morphogenesis; GO:0035108 limb morphogenesis; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0001955 blood vessel maturation; GO:0044703 multi-organism reproductive process; GO:0035136 forelimb morphogenesis; GO:0051248 negative regulation of protein metabolic process; GO:0040012 regulation of locomotion; GO:0043412 macromolecule modification; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044464 cell part; GO:0071944 cell periphery; GO:0044425 membrane part; GO:0031225 anchored component of membrane; GO:0031224 intrinsic component of membrane; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; ","GO:0004867 serine-type endopeptidase inhibitor activity; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0030414 peptidase inhibitor activity; GO:0061134 peptidase regulator activity; GO:0008191 metalloendopeptidase inhibitor activity; GO:0005515 protein binding; GO:0061135 endopeptidase regulator activity; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0004866 endopeptidase inhibitor activity; ","K17461","RECK; reversion-inducing-cysteine-rich protein with kazal motifs","hsa05206 MicroRNAs in cancer - Homo sapiens (human); ","IPR002350; ","Kazal domain; \r"]
["O95989","Diphosphoinositol polyphosphate phosphohydrolase 1 OS=Homo sapiens OX=9606 GN=NUDT3","NUDT3",19.471,8.7071,14,2,2,2,0.946,1.018,1.097,1.016,0.97,0.962,0.963,0.477,"nucleus\r","GO:0044700 single organism signaling; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0015961 diadenosine polyphosphate catabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:1901910 adenosine 5'-(hexahydrogen pentaphosphate) metabolic process; GO:0006066 alcohol metabolic process; GO:1901911 adenosine 5'-(hexahydrogen pentaphosphate) catabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071543 diphosphoinositol polyphosphate metabolic process; GO:0008152 metabolic process; GO:1901292 nucleoside phosphate catabolic process; GO:0007154 cell communication; GO:0006195 purine nucleotide catabolic process; GO:0046130 purine ribonucleoside catabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0019693 ribose phosphate metabolic process; GO:1901361 organic cyclic compound catabolic process; GO:1901907 diadenosine pentaphosphate catabolic process; GO:0009125 nucleoside monophosphate catabolic process; GO:0009158 ribonucleoside monophosphate catabolic process; GO:0009166 nucleotide catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0072521 purine-containing compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0023052 signaling; GO:0071544 diphosphoinositol polyphosphate catabolic process; GO:0009154 purine ribonucleotide catabolic process; GO:1901908 diadenosine hexaphosphate metabolic process; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0006152 purine nucleoside catabolic process; GO:0007267 cell-cell signaling; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0015959 diadenosine polyphosphate metabolic process; GO:1901615 organic hydroxy compound metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:1901906 diadenosine pentaphosphate metabolic process; GO:0046434 organophosphate catabolic process; GO:0009259 ribonucleotide metabolic process; GO:1901909 diadenosine hexaphosphate catabolic process; GO:0009169 purine ribonucleoside monophosphate catabolic process; GO:0046164 alcohol catabolic process; GO:0072523 purine-containing compound catabolic process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0042454 ribonucleoside catabolic process; GO:1901616 organic hydroxy compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0009128 purine nucleoside monophosphate catabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0044248 cellular catabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0009119 ribonucleoside metabolic process; GO:0071545 inositol phosphate catabolic process; GO:0044712 single-organism catabolic process; GO:1901658 glycosyl compound catabolic process; GO:0006807 nitrogen compound metabolic process; GO:1901136 carbohydrate derivative catabolic process; GO:0044282 small molecule catabolic process; GO:0044238 primary metabolic process; GO:0019751 polyol metabolic process; GO:0009261 ribonucleotide catabolic process; GO:0006163 purine nucleotide metabolic process; GO:0046128 purine ribonucleoside metabolic process; GO:1901565 organonitrogen compound catabolic process; GO:0006793 phosphorus metabolic process; GO:0019637 organophosphate metabolic process; GO:0043647 inositol phosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0009164 nucleoside catabolic process; GO:0009056 catabolic process; GO:0046174 polyol catabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0046700 heterocycle catabolic process; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0004551 nucleotide diphosphatase activity; GO:0000287 magnesium ion binding; GO:0052841 inositol bisdiphosphate tetrakisphosphate diphosphatase activity; GO:0050072 m7G(5')pppN diphosphatase activity; GO:0052844 inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity; GO:0034431 bis(5'-adenosyl)-hexaphosphatase activity; GO:0043167 ion binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity; GO:0016787 hydrolase activity; GO:0052842 inositol diphosphate pentakisphosphate diphosphatase activity; GO:0052843 inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity; GO:0052845 inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0052848 inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity; GO:0052846 inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0034432 bis(5'-adenosyl)-pentaphosphatase activity; GO:0000298 endopolyphosphatase activity; GO:0052847 inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity; GO:0052840 inositol diphosphate tetrakisphosphate diphosphatase activity; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; ","K07766",null,null,"IPR015797; IPR000086; ","NUDIX hydrolase domain-like; NUDIX hydrolase domain; \r"]
["O95999","B-cell lymphoma/leukemia 10 OS=Homo sapiens OX=9606 GN=BCL10","BCL10",26.251,8.5629,15.9,4,4,4,0.962,0.905,0.795,1.124,1.087,1.096,1.242,0.0183,"cytoplasm\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0002694 regulation of leukocyte activation; GO:0010941 regulation of cell death; GO:0035148 tube formation; GO:0043009 chordate embryonic development; GO:0009891 positive regulation of biosynthetic process; GO:0031347 regulation of defense response; GO:0044237 cellular metabolic process; GO:0009607 response to biotic stimulus; GO:0008152 metabolic process; GO:0065003 macromolecular complex assembly; GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling; GO:0044093 positive regulation of molecular function; GO:0071706 tumor necrosis factor superfamily cytokine production; GO:0009790 embryo development; GO:0048598 embryonic morphogenesis; GO:0052548 regulation of endopeptidase activity; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0071214 cellular response to abiotic stimulus; GO:0010950 positive regulation of endopeptidase activity; GO:0080090 regulation of primary metabolic process; GO:0035239 tube morphogenesis; GO:0002905 regulation of mature B cell apoptotic process; GO:0044763 single-organism cellular process; GO:0070229 negative regulation of lymphocyte apoptotic process; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0051291 protein heterooligomerization; GO:0051092 positive regulation of NF-kappaB transcription factor activity; GO:0002223 stimulatory C-type lectin receptor signaling pathway; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0032765 positive regulation of mast cell cytokine production; GO:0060548 negative regulation of cell death; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0002009 morphogenesis of an epithelium; GO:0044707 single-multicellular organism process; GO:0032677 regulation of interleukin-8 production; GO:0002718 regulation of cytokine production involved in immune response; GO:2001056 positive regulation of cysteine-type endopeptidase activity; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0001819 positive regulation of cytokine production; GO:0048519 negative regulation of biological process; GO:0019724 B cell mediated immunity; GO:0009653 anatomical structure morphogenesis; GO:0001783 B cell apoptotic process; GO:0050867 positive regulation of cell activation; GO:0051345 positive regulation of hydrolase activity; GO:0009889 regulation of biosynthetic process; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:1902680 positive regulation of RNA biosynthetic process; GO:0016331 morphogenesis of embryonic epithelium; GO:0038093 Fc receptor signaling pathway; GO:0042089 cytokine biosynthetic process; GO:0002449 lymphocyte mediated immunity; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0050778 positive regulation of immune response; GO:0060562 epithelial tube morphogenesis; GO:0045785 positive regulation of cell adhesion; GO:0016567 protein ubiquitination; GO:0006950 response to stress; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:1903039 positive regulation of leukocyte cell-cell adhesion; GO:1901576 organic substance biosynthetic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0002696 positive regulation of leukocyte activation; GO:0032641 lymphotoxin A production; GO:0031398 positive regulation of protein ubiquitination; GO:0032446 protein modification by small protein conjugation; GO:0001816 cytokine production; GO:0031325 positive regulation of cellular metabolic process; GO:0043412 macromolecule modification; GO:0006955 immune response; GO:2000107 negative regulation of leukocyte apoptotic process; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response; GO:0031396 regulation of protein ubiquitination; GO:2001141 regulation of RNA biosynthetic process; GO:0048729 tissue morphogenesis; GO:0007165 signal transduction; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0006915 apoptotic process; GO:0002221 pattern recognition receptor signaling pathway; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0042035 regulation of cytokine biosynthetic process; GO:0045937 positive regulation of phosphate metabolic process; GO:0031326 regulation of cellular biosynthetic process; GO:2000116 regulation of cysteine-type endopeptidase activity; GO:0002237 response to molecule of bacterial origin; GO:0002700 regulation of production of molecular mediator of immune response; GO:0023052 signaling; GO:0002764 immune response-regulating signaling pathway; GO:0010942 positive regulation of cell death; GO:0050856 regulation of T cell receptor signaling pathway; GO:2001236 regulation of extrinsic apoptotic signaling pathway; GO:0065009 regulation of molecular function; GO:0006952 defense response; GO:0036211 protein modification process; GO:0070271 protein complex biogenesis; GO:0070228 regulation of lymphocyte apoptotic process; GO:0016043 cellular component organization; GO:0071260 cellular response to mechanical stimulus; GO:0043069 negative regulation of programmed cell death; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:0042109 lymphotoxin A biosynthetic process; GO:0060255 regulation of macromolecule metabolic process; GO:0043065 positive regulation of apoptotic process; GO:0070231 T cell apoptotic process; GO:0051707 response to other organism; GO:0045087 innate immune response; GO:0071704 organic substance metabolic process; GO:0072175 epithelial tube formation; GO:0009612 response to mechanical stimulus; GO:0045862 positive regulation of proteolysis; GO:0032757 positive regulation of interleukin-8 production; GO:0043066 negative regulation of apoptotic process; GO:0023056 positive regulation of signaling; GO:2001235 positive regulation of apoptotic signaling pathway; GO:0002757 immune response-activating signal transduction; GO:0010647 positive regulation of cell communication; GO:0009059 macromolecule biosynthetic process; GO:0006355 regulation of transcription, DNA-templated; GO:0035556 intracellular signal transduction; GO:0009792 embryo development ending in birth or egg hatching; GO:0002699 positive regulation of immune effector process; GO:0045414 regulation of interleukin-8 biosynthetic process; GO:0022407 regulation of cell-cell adhesion; GO:0043933 macromolecular complex subunit organization; GO:0043085 positive regulation of catalytic activity; GO:0014020 primary neural tube formation; GO:0002720 positive regulation of cytokine production involved in immune response; GO:2000106 regulation of leukocyte apoptotic process; GO:0050852 T cell receptor signaling pathway; GO:0008219 cell death; GO:0002684 positive regulation of immune system process; GO:0038095 Fc-epsilon receptor signaling pathway; GO:0001817 regulation of cytokine production; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0016064 immunoglobulin mediated immune response; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0002220 innate immune response activating cell surface receptor signaling pathway; GO:0007166 cell surface receptor signaling pathway; GO:0042108 positive regulation of cytokine biosynthetic process; GO:0002903 negative regulation of B cell apoptotic process; GO:0009605 response to external stimulus; GO:0051240 positive regulation of multicellular organismal process; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0007399 nervous system development; GO:0002443 leukocyte mediated immunity; GO:0051174 regulation of phosphorus metabolic process; GO:0009620 response to fungus; GO:0002758 innate immune response-activating signal transduction; GO:0045893 positive regulation of transcription, DNA-templated; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0051090 regulation of sequence-specific DNA binding transcription factor activity; GO:0010604 positive regulation of macromolecule metabolic process; GO:0002682 regulation of immune system process; GO:0006464 cellular protein modification process; GO:0043068 positive regulation of programmed cell death; GO:0010952 positive regulation of peptidase activity; GO:0045416 positive regulation of interleukin-8 biosynthetic process; GO:0050794 regulation of cellular process; GO:0051260 protein homooligomerization; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0043067 regulation of programmed cell death; GO:0044267 cellular protein metabolic process; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:0032844 regulation of homeostatic process; GO:0051239 regulation of multicellular organismal process; GO:0051259 protein oligomerization; GO:0060606 tube closure; GO:0031349 positive regulation of defense response; GO:0010628 positive regulation of gene expression; GO:0051171 regulation of nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:0001843 neural tube closure; GO:0009617 response to bacterium; GO:0006461 protein complex assembly; GO:0002253 activation of immune response; GO:0051254 positive regulation of RNA metabolic process; GO:1902531 regulation of intracellular signal transduction; GO:0032094 response to food; GO:0070227 lymphocyte apoptotic process; GO:0048731 system development; GO:0071496 cellular response to external stimulus; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0030155 regulation of cell adhesion; GO:0051247 positive regulation of protein metabolic process; GO:0050870 positive regulation of T cell activation; GO:0007249 I-kappaB kinase/NF-kappaB signaling; GO:0012501 programmed cell death; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0048584 positive regulation of response to stimulus; GO:0031328 positive regulation of cellular biosynthetic process; GO:0050863 regulation of T cell activation; GO:0001841 neural tube formation; GO:0002702 positive regulation of production of molecular mediator of immune response; GO:1902533 positive regulation of intracellular signal transduction; GO:0051249 regulation of lymphocyte activation; GO:2001238 positive regulation of extrinsic apoptotic signaling pathway; GO:0002906 negative regulation of mature B cell apoptotic process; GO:2001233 regulation of apoptotic signaling pathway; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0045088 regulation of innate immune response; GO:0002250 adaptive immune response; GO:0032763 regulation of mast cell cytokine production; GO:0042107 cytokine metabolic process; GO:0002902 regulation of B cell apoptotic process; GO:0002697 regulation of immune effector process; GO:0050851 antigen receptor-mediated signaling pathway; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0035295 tube development; GO:0060429 epithelium development; GO:0071822 protein complex subunit organization; GO:0009888 tissue development; GO:0048522 positive regulation of cellular process; GO:0051251 positive regulation of lymphocyte activation; GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity; GO:0070647 protein modification by small protein conjugation or removal; GO:0002683 negative regulation of immune system process; GO:0050865 regulation of cell activation; GO:0032268 regulation of cellular protein metabolic process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0002224 toll-like receptor signaling pathway; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0052547 regulation of peptidase activity; GO:0048856 anatomical structure development; GO:0071887 leukocyte apoptotic process; GO:0002218 activation of innate immune response; GO:0002252 immune effector process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0021915 neural tube development; GO:0009991 response to extracellular stimulus; GO:1903322 positive regulation of protein modification by small protein conjugation or removal; GO:0050854 regulation of antigen receptor-mediated signaling pathway; GO:0042226 interleukin-6 biosynthetic process; GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0009987 cellular process; GO:0045089 positive regulation of innate immune response; GO:0022409 positive regulation of cell-cell adhesion; GO:0031401 positive regulation of protein modification process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0032845 negative regulation of homeostatic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0001838 embryonic epithelial tube formation; GO:0006968 cellular defense response; GO:0051246 regulation of protein metabolic process; GO:0032635 interleukin-6 production; GO:0044767 single-organism developmental process; GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0009967 positive regulation of signal transduction; GO:0031667 response to nutrient levels; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005874 microtubule; GO:0005881 cytoplasmic microtubule; GO:0098857 membrane microdomain; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0015630 microtubule cytoskeleton; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005764 lysosome; GO:0098589 membrane region; GO:0048471 perinuclear region of cytoplasm; GO:0045121 membrane raft; GO:0043227 membrane-bounded organelle; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0005829 cytosol; GO:0005886 plasma membrane; GO:0099081 supramolecular polymer; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0001772 immunological synapse; GO:0005773 vacuole; GO:0043234 protein complex; GO:0032449 CBM complex; GO:0044444 cytoplasmic part; ","GO:0031625 ubiquitin protein ligase binding; GO:0043621 protein self-association; GO:0019901 protein kinase binding; GO:0005515 protein binding; GO:0003712 transcription cofactor activity; GO:0019900 kinase binding; GO:0032182 ubiquitin-like protein binding; GO:0043422 protein kinase B binding; GO:0002020 protease binding; GO:0042802 identical protein binding; GO:0005488 binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0043130 ubiquitin binding; GO:0051059 NF-kappaB binding; GO:0003713 transcription coactivator activity; GO:0008022 protein C-terminus binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0000988 transcription factor activity, protein binding; GO:0019899 enzyme binding; GO:0008134 transcription factor binding; ","K07368","BCL10; B-cell CLL/lymphoma 10","hsa05152 Tuberculosis - Homo sapiens (human); hsa04660 T cell receptor signaling pathway - Homo sapiens (human); hsa04625 C-type lectin receptor signaling pathway - Homo sapiens (human); hsa04662 B cell receptor signaling pathway - Homo sapiens (human); hsa04064 NF-kappa B signaling pathway - Homo sapiens (human); ","IPR011029; IPR001315; ","Death-like domain; CARD domain; \r"]
["O96000","NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 OS=Homo sapiens OX=9606 GN=NDUFB10","NDUFB10",20.776,18.216,37.2,6,6,6,1.103,1.024,1.069,0.942,1.034,0.845,0.883,0.109,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0022607 cellular component assembly; GO:0006753 nucleoside phosphate metabolic process; GO:0065003 macromolecular complex assembly; GO:0007005 mitochondrion organization; GO:0019693 ribose phosphate metabolic process; GO:0071822 protein complex subunit organization; GO:0010257 NADH dehydrogenase complex assembly; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0006119 oxidative phosphorylation; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0006120 mitochondrial electron transport, NADH to ubiquinone; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0097031 mitochondrial respiratory chain complex I biogenesis; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0022900 electron transport chain; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0070271 protein complex biogenesis; GO:0033108 mitochondrial respiratory chain complex assembly; GO:0016043 cellular component organization; GO:0016310 phosphorylation; GO:0006725 cellular aromatic compound metabolic process; GO:0042773 ATP synthesis coupled electron transport; GO:0009259 ribonucleotide metabolic process; GO:0022904 respiratory electron transport chain; GO:0071704 organic substance metabolic process; GO:0032981 mitochondrial respiratory chain complex I assembly; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0009119 ribonucleoside metabolic process; GO:0006461 protein complex assembly; GO:0043623 cellular protein complex assembly; GO:0046034 ATP metabolic process; GO:0034622 cellular macromolecular complex assembly; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0045333 cellular respiration; GO:0006163 purine nucleotide metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0046128 purine ribonucleoside metabolic process; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:1901564 organonitrogen compound metabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0045271 respiratory chain complex I; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0098798 mitochondrial protein complex; GO:0005747 mitochondrial respiratory chain complex I; GO:0005623 cell; GO:0044455 mitochondrial membrane part; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0070062 extracellular exosome; GO:1902494 catalytic complex; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0019866 organelle inner membrane; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0098803 respiratory chain complex; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005746 mitochondrial respiratory chain; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0030964 NADH dehydrogenase complex; GO:0031975 envelope; GO:1990204 oxidoreductase complex; GO:0043234 protein complex; GO:0031966 mitochondrial membrane; GO:0070469 respiratory chain; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:0003954 NADH dehydrogenase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0050136 NADH dehydrogenase (quinone) activity; GO:0005515 protein binding; GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; GO:0008137 NADH dehydrogenase (ubiquinone) activity; GO:0016491 oxidoreductase activity; ","K03966","NDUFB10; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10","hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); "]
["O96008","Mitochondrial import receptor subunit TOM40 homolog OS=Homo sapiens OX=9606 GN=TOMM40","TOMM40",37.893,10.837,8.6,3,5,3,0.896,0.953,0.857,1.144,1.125,1.026,1.218,0.0126,"nucleus\r","GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0072594 establishment of protein localization to organelle; GO:0017038 protein import; GO:0006839 mitochondrial transport; GO:0044699 single-organism process; GO:0006914 autophagy; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:1902578 single-organism localization; GO:1990542 mitochondrial transmembrane transport; GO:0007005 mitochondrion organization; GO:0065002 intracellular protein transmembrane transport; GO:0006886 intracellular protein transport; GO:0044248 cellular catabolic process; GO:0006626 protein targeting to mitochondrion; GO:1902580 single-organism cellular localization; GO:0033365 protein localization to organelle; GO:0044743 protein transmembrane import into intracellular organelle; GO:0034613 cellular protein localization; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0009987 cellular process; GO:0044765 single-organism transport; GO:0030150 protein import into mitochondrial matrix; GO:0016236 macroautophagy; GO:0071806 protein transmembrane transport; GO:0071702 organic substance transport; GO:0070585 protein localization to mitochondrion; GO:1902582 single-organism intracellular transport; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:0055085 transmembrane transport; GO:0070727 cellular macromolecule localization; GO:0006811 ion transport; GO:0006996 organelle organization; GO:0051179 localization; GO:0009056 catabolic process; GO:0072655 establishment of protein localization to mitochondrion; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0019867 outer membrane; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0031306 intrinsic component of mitochondrial outer membrane; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0005740 mitochondrial envelope; GO:0031301 integral component of organelle membrane; GO:0031307 integral component of mitochondrial outer membrane; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0031968 organelle outer membrane; GO:0005742 mitochondrial outer membrane translocase complex; GO:0043227 membrane-bounded organelle; GO:0098799 outer mitochondrial membrane protein complex; GO:0098573 intrinsic component of mitochondrial membrane; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0044429 mitochondrial part; GO:0046930 pore complex; GO:0005741 mitochondrial outer membrane; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031975 envelope; GO:0032592 integral component of mitochondrial membrane; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0031966 mitochondrial membrane; GO:0031300 intrinsic component of organelle membrane; GO:0044444 cytoplasmic part; ","GO:0022829 wide pore channel activity; GO:0008565 protein transporter activity; GO:0022884 macromolecule transmembrane transporter activity; GO:0005488 binding; GO:0022803 passive transmembrane transporter activity; GO:0015288 porin activity; GO:0015266 protein channel activity; GO:0022892 substrate-specific transporter activity; GO:0008320 protein transmembrane transporter activity; GO:0005515 protein binding; GO:0015267 channel activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0022857 transmembrane transporter activity; GO:0005215 transporter activity; ","K11518","TOM40; mitochondrial import receptor subunit TOM40","hsa05014 Amyotrophic lateral sclerosis (ALS) - Homo sapiens (human); ","IPR023614; ","Porin domain; \r"]
["O96011","Peroxisomal membrane protein 11B OS=Homo sapiens OX=9606 GN=PEX11B","PEX11B",28.431,3.7273,4.2,1,1,1,0.753,1.05,1.064,1.078,1.103,0.953,1.093,0.461,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0016043 cellular component organization; GO:0065008 regulation of biological quality; GO:0044375 regulation of peroxisome size; GO:0051260 protein homooligomerization; GO:0048285 organelle fission; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0051259 protein oligomerization; GO:0007031 peroxisome organization; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0032535 regulation of cellular component size; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0016559 peroxisome fission; GO:0051716 cellular response to stimulus; GO:0071822 protein complex subunit organization; GO:0044763 single-organism cellular process; GO:0023052 signaling; GO:0043933 macromolecular complex subunit organization; GO:0050789 regulation of biological process; GO:0006996 organelle organization; GO:0090066 regulation of anatomical structure size; GO:0070271 protein complex biogenesis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0044438 microbody part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005778 peroxisomal membrane; GO:0070062 extracellular exosome; GO:0031301 integral component of organelle membrane; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0042579 microbody; GO:1903561 extracellular vesicle; GO:0005779 integral component of peroxisomal membrane; GO:0043227 membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0031903 microbody membrane; GO:0031231 intrinsic component of peroxisomal membrane; GO:0098588 bounding membrane of organelle; GO:0044439 peroxisomal part; GO:0005777 peroxisome; GO:0044446 intracellular organelle part; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0031300 intrinsic component of organelle membrane; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0042802 identical protein binding; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0046983 protein dimerization activity; ","K13352","PEX11B; peroxin-11B","hsa04146 Peroxisome - Homo sapiens (human); "]
["O96019","Actin-like protein 6A OS=Homo sapiens OX=9606 GN=ACTL6A","ACTL6A",47.46,10.801,13.1,5,6,5,0.955,0.889,0.87,1.083,1.094,1.106,1.21,0.00268,"cytoplasm\r","GO:0044700 single organism signaling; GO:1903955 positive regulation of protein targeting to mitochondrion; GO:0097659 nucleic acid-templated transcription; GO:1903533 regulation of protein targeting; GO:0003407 neural retina development; GO:0044237 cellular metabolic process; GO:0010821 regulation of mitochondrion organization; GO:0008152 metabolic process; GO:0032879 regulation of localization; GO:1903747 regulation of establishment of protein localization to mitochondrion; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0032774 RNA biosynthetic process; GO:0043044 ATP-dependent chromatin remodeling; GO:0031323 regulation of cellular metabolic process; GO:0010506 regulation of autophagy; GO:0032501 multicellular organismal process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0007417 central nervous system development; GO:0006473 protein acetylation; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0051223 regulation of protein transport; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0044707 single-multicellular organism process; GO:0006338 chromatin remodeling; GO:0006259 DNA metabolic process; GO:0016570 histone modification; GO:0044267 cellular protein metabolic process; GO:0060341 regulation of cellular localization; GO:0001654 eye development; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0032880 regulation of protein localization; GO:0016569 covalent chromatin modification; GO:0006950 response to stress; GO:0048731 system development; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0006974 cellular response to DNA damage stimulus; GO:1904951 positive regulation of establishment of protein localization; GO:0051276 chromosome organization; GO:0006996 organelle organization; GO:0007423 sensory organ development; GO:0043412 macromolecule modification; GO:1903827 regulation of cellular protein localization; GO:0070646 protein modification by small protein removal; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:1903749 positive regulation of establishment of protein localization to mitochondrion; GO:0051130 positive regulation of cellular component organization; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0043543 protein acylation; GO:0006310 DNA recombination; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0021510 spinal cord development; GO:0018394 peptidyl-lysine acetylation; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0032386 regulation of intracellular transport; GO:0043967 histone H4 acetylation; GO:0070647 protein modification by small protein conjugation or removal; GO:0023052 signaling; GO:0051050 positive regulation of transport; GO:0016070 RNA metabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0010638 positive regulation of organelle organization; GO:0016573 histone acetylation; GO:0019222 regulation of metabolic process; GO:0006325 chromatin organization; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0051222 positive regulation of protein transport; GO:0018393 internal peptidyl-lysine acetylation; GO:0016043 cellular component organization; GO:0043010 camera-type eye development; GO:0040008 regulation of growth; GO:0043968 histone H2A acetylation; GO:0090316 positive regulation of intracellular protein transport; GO:0006725 cellular aromatic compound metabolic process; GO:1903829 positive regulation of cellular protein localization; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0016579 protein deubiquitination; GO:0050896 response to stimulus; GO:0070201 regulation of establishment of protein localization; GO:0071704 organic substance metabolic process; GO:0018205 peptidyl-lysine modification; GO:0006508 proteolysis; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0033157 regulation of intracellular protein transport; GO:0009987 cellular process; GO:0060041 retina development in camera-type eye; GO:0006475 internal protein amino acid acetylation; GO:0006355 regulation of transcription, DNA-templated; GO:0051049 regulation of transport; GO:0032388 positive regulation of intracellular transport; GO:0033043 regulation of organelle organization; GO:0006807 nitrogen compound metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:1903214 regulation of protein targeting to mitochondrion; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0010822 positive regulation of mitochondrion organization; GO:0018193 peptidyl-amino acid modification; GO:0006281 DNA repair; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:1903146 regulation of mitophagy; GO:0044767 single-organism developmental process; GO:0010467 gene expression; GO:0051128 regulation of cellular component organization; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0071944 cell periphery; GO:0097346 INO80-type complex; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0070603 SWI/SNF superfamily-type complex; GO:0005623 cell; GO:0043189 H4/H2A histone acetyltransferase complex; GO:0044422 organelle part; GO:0000123 histone acetyltransferase complex; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0035267 NuA4 histone acetyltransferase complex; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0031248 protein acetyltransferase complex; GO:0070013 intracellular organelle lumen; GO:0044454 nuclear chromosome part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0000790 nuclear chromatin; GO:0071564 npBAF complex; GO:0043227 membrane-bounded organelle; GO:1902493 acetyltransferase complex; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0033202 DNA helicase complex; GO:0043232 intracellular non-membrane-bounded organelle; GO:0031011 Ino80 complex; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:1902562 H4 histone acetyltransferase complex; GO:1990234 transferase complex; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0000785 chromatin; GO:0000228 nuclear chromosome; GO:0043234 protein complex; GO:0090544 BAF-type complex; GO:0016514 SWI/SNF complex; GO:0044428 nuclear part; ","GO:0000989 transcription factor activity, transcription factor binding; GO:0003713 transcription coactivator activity; GO:0005515 protein binding; GO:0003682 chromatin binding; GO:0003712 transcription cofactor activity; GO:0000988 transcription factor activity, protein binding; GO:0005488 binding; ","K11340","ACTL6A; actin-like protein 6A","hsa05225 Hepatocellular carcinoma - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); "]
["P00167","Cytochrome b5 OS=Homo sapiens OX=9606 GN=CYB5A","CYB5A",15.33,75.801,49.3,5,11,5,1.156,1.099,1.136,0.884,0.889,0.89,0.785,3.82E-3,"cytoplasm\r","GO:0034220 ion transmembrane transport; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0006766 vitamin metabolic process; GO:1902578 single-organism localization; GO:0006812 cation transport; GO:0005996 monosaccharide metabolic process; GO:0046686 response to cadmium ion; GO:1902600 hydrogen ion transmembrane transport; GO:0010035 response to inorganic substance; GO:0009987 cellular process; GO:0006767 water-soluble vitamin metabolic process; GO:0044765 single-organism transport; GO:0019852 L-ascorbic acid metabolic process; GO:0098655 cation transmembrane transport; GO:0098660 inorganic ion transmembrane transport; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0005975 carbohydrate metabolic process; GO:0044238 primary metabolic process; GO:0010038 response to metal ion; GO:0006818 hydrogen transport; GO:0015992 proton transport; GO:0006810 transport; GO:0044723 single-organism carbohydrate metabolic process; GO:0055085 transmembrane transport; GO:0042221 response to chemical; GO:0044710 single-organism metabolic process; GO:0006811 ion transport; GO:0019752 carboxylic acid metabolic process; GO:0006082 organic acid metabolic process; GO:0051179 localization; GO:0015672 monovalent inorganic cation transport; GO:0098662 inorganic cation transmembrane transport; GO:0043436 oxoacid metabolic process; ","GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0044421 extracellular region part; GO:0019867 outer membrane; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0005740 mitochondrial envelope; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0031968 organelle outer membrane; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0044429 mitochondrial part; GO:0005741 mitochondrial outer membrane; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044432 endoplasmic reticulum part; GO:0031975 envelope; GO:0043230 extracellular organelle; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0015075 ion transmembrane transporter activity; GO:0043167 ion binding; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0015077 monovalent inorganic cation transmembrane transporter activity; GO:0016676 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor; GO:0016675 oxidoreductase activity, acting on a heme group of donors; GO:0015002 heme-copper terminal oxidase activity; GO:0015078 hydrogen ion transmembrane transporter activity; GO:0016491 oxidoreductase activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0016614 oxidoreductase activity, acting on CH-OH group of donors; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0009055 electron carrier activity; GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; GO:0020037 heme binding; GO:0004129 cytochrome-c oxidase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0004033 aldo-keto reductase (NADP) activity; GO:0022890 inorganic cation transmembrane transporter activity; GO:0046906 tetrapyrrole binding; GO:0019899 enzyme binding; GO:0008324 cation transmembrane transporter activity; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; ",{"$nulls":3},"IPR001199; ","Cytochrome b5-like heme/steroid binding domain; \r"]
["P00325","Alcohol dehydrogenase 1B OS=Homo sapiens OX=9606 GN=ADH1B","ADH1B",39.854,144.06,50.9,19,55,19,1.098,1.059,1.089,0.945,0.901,0.914,0.85,0.000818,"cytoplasm\r","GO:0006069 ethanol oxidation; GO:0008152 metabolic process; GO:1901615 organic hydroxy compound metabolic process; GO:0044710 single-organism metabolic process; GO:0006066 alcohol metabolic process; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0006067 ethanol metabolic process; GO:0044699 single-organism process; GO:0034308 primary alcohol metabolic process; GO:0071704 organic substance metabolic process; ","GO:0016020 membrane; GO:0043229 intracellular organelle; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0016614 oxidoreductase activity, acting on CH-OH group of donors; GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0004022 alcohol dehydrogenase (NAD) activity; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0008270 zinc ion binding; GO:0004024 alcohol dehydrogenase activity, zinc-dependent; GO:0016491 oxidoreductase activity; ","K13951","ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]","hsa05204 Chemical carcinogenesis - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00980 Metabolism of xenobiotics by cytochrome P450 - Homo sapiens (human); hsa00071 Fatty acid degradation - Homo sapiens (human); hsa00982 Drug metabolism - cytochrome P450 - Homo sapiens (human); hsa00350 Tyrosine metabolism - Homo sapiens (human); hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human); hsa00830 Retinol metabolism - Homo sapiens (human); ","IPR011032; IPR020843; IPR016040; IPR013154; IPR013149; ","\"GroES-like; Polyketide synthase, enoylreductase domain; NAD(P)-binding domain; Alcohol dehydrogenase, N-terminal; Alcohol dehydrogenase, C-terminal; \"\r"]
["P00338","L-lactate dehydrogenase A chain OS=Homo sapiens OX=9606 GN=LDHA","LDHA",36.688,91.622,38.6,14,56,13,0.939,0.929,0.933,1.048,1.085,1.05,1.136,0.000399,"cytoplasm\r","GO:0048569 post-embryonic animal organ development; GO:0010941 regulation of cell death; GO:0009116 nucleoside metabolic process; GO:0006165 nucleoside diphosphate phosphorylation; GO:0019362 pyridine nucleotide metabolic process; GO:0006096 glycolytic process; GO:0007420 brain development; GO:0046683 response to organophosphorus; GO:0009185 ribonucleoside diphosphate metabolic process; GO:0009749 response to glucose; GO:0044237 cellular metabolic process; GO:0048857 neural nucleus development; GO:0009605 response to external stimulus; GO:0021762 substantia nigra development; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0009719 response to endogenous stimulus; GO:0032787 monocarboxylic acid metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0009743 response to carbohydrate; GO:0007399 nervous system development; GO:0014070 response to organic cyclic compound; GO:0006089 lactate metabolic process; GO:0030901 midbrain development; GO:0009179 purine ribonucleoside diphosphate metabolic process; GO:0000302 response to reactive oxygen species; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0006732 coenzyme metabolic process; GO:0005975 carbohydrate metabolic process; GO:0032501 multicellular organismal process; GO:1901575 organic substance catabolic process; GO:0010243 response to organonitrogen compound; GO:0048513 animal organ development; GO:0051591 response to cAMP; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0019674 NAD metabolic process; GO:0007417 central nervous system development; GO:0044710 single-organism metabolic process; GO:0034284 response to monosaccharide; GO:1901698 response to nitrogen compound; GO:0009126 purine nucleoside monophosphate metabolic process; GO:0043068 positive regulation of programmed cell death; GO:0043436 oxoacid metabolic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0016310 phosphorylation; GO:1901615 organic hydroxy compound metabolic process; GO:0046496 nicotinamide nucleotide metabolic process; GO:0009628 response to abiotic stimulus; GO:0009259 ribonucleotide metabolic process; GO:1901700 response to oxygen-containing compound; GO:0043067 regulation of programmed cell death; GO:0042493 response to drug; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0014074 response to purine-containing compound; GO:0070482 response to oxygen levels; GO:1901135 carbohydrate derivative metabolic process; GO:0007275 multicellular organism development; GO:0009119 ribonucleoside metabolic process; GO:0006950 response to stress; GO:0048731 system development; GO:0009141 nucleoside triphosphate metabolic process; GO:0010033 response to organic substance; GO:0007584 response to nutrient; GO:0044238 primary metabolic process; GO:0006163 purine nucleotide metabolic process; GO:0006793 phosphorus metabolic process; GO:0042542 response to hydrogen peroxide; GO:0019637 organophosphate metabolic process; GO:0036293 response to decreased oxygen levels; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0006757 ATP generation from ADP; GO:0042278 purine nucleoside metabolic process; GO:0046031 ADP metabolic process; GO:0009746 response to hexose; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0043627 response to estrogen; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0046939 nucleotide phosphorylation; GO:0009135 purine nucleoside diphosphate metabolic process; GO:0072524 pyridine-containing compound metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0006979 response to oxidative stress; GO:0060322 head development; GO:0010035 response to inorganic substance; GO:0032502 developmental process; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0055114 oxidation-reduction process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0051186 cofactor metabolic process; GO:0016052 carbohydrate catabolic process; GO:0010942 positive regulation of cell death; GO:0044723 single-organism carbohydrate metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:1901657 glycosyl compound metabolic process; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:0006725 cellular aromatic compound metabolic process; GO:0043065 positive regulation of apoptotic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0009991 response to extracellular stimulus; GO:0006090 pyruvate metabolic process; GO:0001666 response to hypoxia; GO:0034641 cellular nitrogen compound metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0009132 nucleoside diphosphate metabolic process; GO:0046034 ATP metabolic process; GO:0044724 single-organism carbohydrate catabolic process; GO:0044712 single-organism catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0048518 positive regulation of biological process; GO:0046128 purine ribonucleoside metabolic process; GO:0044767 single-organism developmental process; GO:0019752 carboxylic acid metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0031667 response to nutrient levels; GO:0009056 catabolic process; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0019900 kinase binding; GO:0048037 cofactor binding; GO:0016491 oxidoreductase activity; GO:0016614 oxidoreductase activity, acting on CH-OH group of donors; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; GO:0050839 cell adhesion molecule binding; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0051287 NAD binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0004457 lactate dehydrogenase activity; GO:0004459 L-lactate dehydrogenase activity; GO:0019899 enzyme binding; GO:0036094 small molecule binding; GO:0050662 coenzyme binding; ","K00016","LDH; L-lactate dehydrogenase [EC:1.1.1.27]","hsa00640 Propanoate metabolism - Homo sapiens (human); hsa00620 Pyruvate metabolism - Homo sapiens (human); hsa04066 HIF-1 signaling pathway - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00270 Cysteine and methionine metabolism - Homo sapiens (human); hsa04922 Glucagon signaling pathway - Homo sapiens (human); hsa05230 Central carbon metabolism in cancer - Homo sapiens (human); hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human); ","IPR022383; IPR016040; IPR001236; IPR015955; ","\"Lactate/malate dehydrogenase, C-terminal; NAD(P)-binding domain; Lactate/malate dehydrogenase, N-terminal; Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal; \"\r"]
["P00352","Retinal dehydrogenase 1 OS=Homo sapiens OX=9606 GN=ALDH1A1","ALDH1A1",54.861,190.86,30.5,15,22,12,1.066,1.136,1.111,0.895,0.902,0.9,0.814,8.26E-3,"cytoplasm\r","GO:0046365 monosaccharide catabolic process; GO:0065008 regulation of biological quality; GO:0006069 ethanol oxidation; GO:1901615 organic hydroxy compound metabolic process; GO:0006066 alcohol metabolic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0061624 fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0019682 glyceraldehyde-3-phosphate metabolic process; GO:0051345 positive regulation of hydrolase activity; GO:0044093 positive regulation of molecular function; GO:0005996 monosaccharide metabolic process; GO:0006067 ethanol metabolic process; GO:0001523 retinoid metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034308 primary alcohol metabolic process; GO:0009987 cellular process; GO:0006629 lipid metabolic process; GO:0006720 isoprenoid metabolic process; GO:0042445 hormone metabolic process; GO:0044724 single-organism carbohydrate catabolic process; GO:0043547 positive regulation of GTPase activity; GO:0055114 oxidation-reduction process; GO:0044712 single-organism catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006081 cellular aldehyde metabolic process; GO:0044282 small molecule catabolic process; GO:0005975 carbohydrate metabolic process; GO:0044238 primary metabolic process; GO:0034754 cellular hormone metabolic process; GO:0016052 carbohydrate catabolic process; GO:0043085 positive regulation of catalytic activity; GO:0044723 single-organism carbohydrate metabolic process; GO:1901575 organic substance catabolic process; GO:0042572 retinol metabolic process; GO:0006000 fructose metabolic process; GO:0051336 regulation of hydrolase activity; GO:0006793 phosphorus metabolic process; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0010817 regulation of hormone levels; GO:0019637 organophosphate metabolic process; GO:0065009 regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0016101 diterpenoid metabolic process; GO:0006721 terpenoid metabolic process; GO:0019320 hexose catabolic process; GO:0006001 fructose catabolic process; GO:0009056 catabolic process; GO:0019318 hexose metabolic process; GO:0065007 biological regulation; ","GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0018479 benzaldehyde dehydrogenase (NAD+) activity; GO:0042562 hormone binding; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0030695 GTPase regulator activity; GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors; GO:0001758 retinal dehydrogenase activity; GO:0000166 nucleotide binding; GO:0098772 molecular function regulator; GO:0004029 aldehyde dehydrogenase (NAD) activity; GO:0016491 oxidoreductase activity; GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0005497 androgen binding; GO:0030234 enzyme regulator activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0008047 enzyme activator activity; GO:0005096 GTPase activator activity; GO:0036094 small molecule binding; ","K07249","ALDH1A; retinal dehydrogenase [EC:1.2.1.36]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00830 Retinol metabolism - Homo sapiens (human); ","IPR016161; IPR015590; IPR016162; IPR016163; ","\"Aldehyde/histidinol dehydrogenase; Aldehyde dehydrogenase domain; Aldehyde dehydrogenase N-terminal domain; Aldehyde dehydrogenase, C-terminal; \"\r"]
["P00367","Glutamate dehydrogenase 1, mitochondrial OS=Homo sapiens OX=9606 GN=GLUD1","GLUD1",61.397,205.41,45.5,24,47,24,1.086,1.055,1.078,0.924,0.948,0.928,0.87,0.000285,"mitochondria\r","GO:1901606 alpha-amino acid catabolic process; GO:0065008 regulation of biological quality; GO:0016053 organic acid biosynthetic process; GO:0007420 brain development; GO:0050796 regulation of insulin secretion; GO:0023051 regulation of signaling; GO:0051046 regulation of secretion; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0002793 positive regulation of peptide secretion; GO:0044237 cellular metabolic process; GO:0009084 glutamine family amino acid biosynthetic process; GO:0048857 neural nucleus development; GO:0021762 substantia nigra development; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0010646 regulation of cell communication; GO:0032879 regulation of localization; GO:1901607 alpha-amino acid biosynthetic process; GO:0060322 head development; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0072350 tricarboxylic acid metabolic process; GO:0030901 midbrain development; GO:0006537 glutamate biosynthetic process; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:1903530 regulation of secretion by cell; GO:0032501 multicellular organismal process; GO:0051050 positive regulation of transport; GO:0046395 carboxylic acid catabolic process; GO:1901575 organic substance catabolic process; GO:0043650 dicarboxylic acid biosynthetic process; GO:0048513 animal organ development; GO:0046394 carboxylic acid biosynthetic process; GO:0046883 regulation of hormone secretion; GO:0050789 regulation of biological process; GO:1903532 positive regulation of secretion by cell; GO:0007417 central nervous system development; GO:0044710 single-organism metabolic process; GO:0009065 glutamine family amino acid catabolic process; GO:0050714 positive regulation of protein secretion; GO:0010817 regulation of hormone levels; GO:0009063 cellular amino acid catabolic process; GO:0051223 regulation of protein transport; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:0051222 positive regulation of protein transport; GO:0043436 oxoacid metabolic process; GO:0051047 positive regulation of secretion; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0043648 dicarboxylic acid metabolic process; GO:0006541 glutamine metabolic process; GO:0006538 glutamate catabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0090277 positive regulation of peptide hormone secretion; GO:0070201 regulation of establishment of protein localization; GO:0071704 organic substance metabolic process; GO:0002791 regulation of peptide secretion; GO:0043649 dicarboxylic acid catabolic process; GO:0023056 positive regulation of signaling; GO:0006536 glutamate metabolic process; GO:0044248 cellular catabolic process; GO:0007275 multicellular organism development; GO:0010647 positive regulation of cell communication; GO:0032880 regulation of protein localization; GO:0050708 regulation of protein secretion; GO:0009987 cellular process; GO:0009064 glutamine family amino acid metabolic process; GO:0090087 regulation of peptide transport; GO:0032024 positive regulation of insulin secretion; GO:0008652 cellular amino acid biosynthetic process; GO:0044711 single-organism biosynthetic process; GO:0048731 system development; GO:0044712 single-organism catabolic process; GO:0051049 regulation of transport; GO:0006807 nitrogen compound metabolic process; GO:0044282 small molecule catabolic process; GO:1901605 alpha-amino acid metabolic process; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:1901565 organonitrogen compound catabolic process; GO:1904951 positive regulation of establishment of protein localization; GO:0044767 single-organism developmental process; GO:0016054 organic acid catabolic process; GO:0019752 carboxylic acid metabolic process; GO:0046887 positive regulation of hormone secretion; GO:0090276 regulation of peptide hormone secretion; GO:0044283 small molecule biosynthetic process; GO:0009056 catabolic process; GO:0065007 biological regulation; GO:1901564 organonitrogen compound metabolic process; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0016597 amino acid binding; GO:1901265 nucleoside phosphate binding; GO:0005515 protein binding; GO:0070403 NAD+ binding; GO:0070728 leucine binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0042802 identical protein binding; GO:0031406 carboxylic acid binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043531 ADP binding; GO:0043169 cation binding; GO:0004353 glutamate dehydrogenase [NAD(P)+] activity; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0043177 organic acid binding; GO:0000166 nucleotide binding; GO:0004352 glutamate dehydrogenase (NAD+) activity; GO:0048037 cofactor binding; GO:0016491 oxidoreductase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0051287 NAD binding; GO:0032555 purine ribonucleotide binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors; GO:0036094 small molecule binding; GO:0050662 coenzyme binding; ","K00261","GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa04964 Proximal tubule bicarbonate reclamation - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); hsa04217 Necroptosis - Homo sapiens (human); hsa00220 Arginine biosynthesis - Homo sapiens (human); hsa00910 Nitrogen metabolism - Homo sapiens (human); hsa00250 Alanine, aspartate and glutamate metabolism - Homo sapiens (human); hsa00471 D-Glutamine and D-glutamate metabolism - Homo sapiens (human); ","IPR006096; IPR016040; IPR033922; IPR006097; ","\"Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal; NAD(P)-binding domain; NAD(P) binding domain of glutamate dehydrogenase; Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain; \"\r"]
["P00387","NADH-cytochrome b5 reductase 3 OS=Homo sapiens OX=9606 GN=CYB5R3","CYB5R3",34.234,236.72,64.8,15,38,15,1.133,1.1,1.127,0.895,0.837,0.881,0.778,0.000342,"extracellular\r","GO:0045321 leukocyte activation; GO:0006066 alcohol metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0008610 lipid biosynthetic process; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0070887 cellular response to chemical stimulus; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0006629 lipid metabolic process; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0055114 oxidation-reduction process; GO:0002446 neutrophil mediated immunity; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0008202 steroid metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:1901617 organic hydroxy compound biosynthetic process; GO:0005975 carbohydrate metabolic process; GO:0032501 multicellular organismal process; GO:0002444 myeloid leukocyte mediated immunity; GO:0006810 transport; GO:0044723 single-organism carbohydrate metabolic process; GO:0042221 response to chemical; GO:0032940 secretion by cell; GO:0044710 single-organism metabolic process; GO:0043299 leukocyte degranulation; GO:0003013 circulatory system process; GO:0006082 organic acid metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0043436 oxoacid metabolic process; GO:0071466 cellular response to xenobiotic stimulus; GO:0002283 neutrophil activation involved in immune response; GO:1901615 organic hydroxy compound metabolic process; GO:1902652 secondary alcohol metabolic process; GO:0002252 immune effector process; GO:1902653 secondary alcohol biosynthetic process; GO:0050896 response to stimulus; GO:0016125 sterol metabolic process; GO:0071704 organic substance metabolic process; GO:0016126 sterol biosynthetic process; GO:0006766 vitamin metabolic process; GO:0006805 xenobiotic metabolic process; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0009410 response to xenobiotic stimulus; GO:0006695 cholesterol biosynthetic process; GO:0008015 blood circulation; GO:0005996 monosaccharide metabolic process; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0006767 water-soluble vitamin metabolic process; GO:0019852 L-ascorbic acid metabolic process; GO:0008203 cholesterol metabolic process; GO:0003008 system process; GO:0044711 single-organism biosynthetic process; GO:0016192 vesicle-mediated transport; GO:0046165 alcohol biosynthetic process; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:0043312 neutrophil degranulation; GO:0002263 cell activation involved in immune response; GO:1901576 organic substance biosynthetic process; GO:0002366 leukocyte activation involved in immune response; GO:0006694 steroid biosynthetic process; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0044283 small molecule biosynthetic process; GO:0019752 carboxylic acid metabolic process; GO:0001775 cell activation; GO:0006955 immune response; GO:0051179 localization; GO:0006887 exocytosis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0019867 outer membrane; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0005789 endoplasmic reticulum membrane; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0031967 organelle envelope; GO:0005833 hemoglobin complex; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0042582 azurophil granule; GO:0043231 intracellular membrane-bounded organelle; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0031975 envelope; GO:0005773 vacuole; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0031966 mitochondrial membrane; GO:0034774 secretory granule lumen; GO:0005783 endoplasmic reticulum; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0044464 cell part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0019866 organelle inner membrane; GO:0031968 organelle outer membrane; GO:0044445 cytosolic part; GO:0030141 secretory granule; GO:0005811 lipid particle; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0044429 mitochondrial part; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005741 mitochondrial outer membrane; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0043226 organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0044432 endoplasmic reticulum part; GO:0044444 cytoplasmic part; ","GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:1901265 nucleoside phosphate binding; GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor; GO:0050660 flavin adenine dinucleotide binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0000166 nucleotide binding; GO:0048037 cofactor binding; GO:0016491 oxidoreductase activity; GO:0071949 FAD binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016208 AMP binding; GO:0051287 NAD binding; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H; GO:0032550 purine ribonucleoside binding; GO:0043531 ADP binding; GO:0043169 cation binding; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0017076 purine nucleotide binding; GO:0050662 coenzyme binding; GO:0036094 small molecule binding; ","K00326","E1.6.2.2; cytochrome-b5 reductase [EC:1.6.2.2]","hsa00520 Amino sugar and nucleotide sugar metabolism - Homo sapiens (human); ","IPR017927; IPR001433; IPR008333; IPR017938; IPR001709; ","\"Ferredoxin reductase-type FAD-binding domain; Oxidoreductase FAD/NAD(P)-binding; Oxidoreductase, FAD-binding domain; Riboflavin synthase-like beta-barrel; Flavoprotein pyridine nucleotide cytochrome reductase; \"\r"]
["P00390","Glutathione reductase, mitochondrial OS=Homo sapiens OX=9606 GN=GSR","GSR",56.256,40.767,16.7,7,11,7,1.057,1.101,1.025,0.947,0.963,0.898,0.882,0.0132,"mitochondria\r","GO:0050794 regulation of cellular process; GO:0065008 regulation of biological quality; GO:0006518 peptide metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0015949 nucleobase-containing small molecule interconversion; GO:0045454 cell redox homeostasis; GO:1901700 response to oxygen-containing compound; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0008152 metabolic process; GO:1990748 cellular detoxification; GO:0006575 cellular modified amino acid metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0006979 response to oxidative stress; GO:0006749 glutathione metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0098869 cellular oxidant detoxification; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0006790 sulfur compound metabolic process; GO:0006950 response to stress; GO:0055114 oxidation-reduction process; GO:0009636 response to toxic substance; GO:0044281 small molecule metabolic process; GO:0000302 response to reactive oxygen species; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0019725 cellular homeostasis; GO:0043603 cellular amide metabolic process; GO:0044238 primary metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0044710 single-organism metabolic process; GO:0098754 detoxification; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0009897 external side of plasma membrane; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0098552 side of membrane; GO:0043229 intracellular organelle; GO:0005759 mitochondrial matrix; GO:0044429 mitochondrial part; GO:0044446 intracellular organelle part; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0009986 cell surface; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:1901265 nucleoside phosphate binding; GO:0050660 flavin adenine dinucleotide binding; GO:0043167 ion binding; GO:0016209 antioxidant activity; GO:0000166 nucleotide binding; GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor; GO:0048037 cofactor binding; GO:0004362 glutathione-disulfide reductase activity; GO:0016491 oxidoreductase activity; GO:0009055 electron carrier activity; GO:0015036 disulfide oxidoreductase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0050661 NADP binding; GO:0016667 oxidoreductase activity, acting on a sulfur group of donors; GO:0015038 glutathione disulfide oxidoreductase activity; GO:0043168 anion binding; GO:0015037 peptide disulfide oxidoreductase activity; GO:0050662 coenzyme binding; GO:0036094 small molecule binding; ","K00383","GSR; glutathione reductase (NADPH) [EC:1.8.1.7]","hsa00480 Glutathione metabolism - Homo sapiens (human); hsa04918 Thyroid hormone synthesis - Homo sapiens (human); ","IPR016156; IPR004099; IPR023753; ","\"FAD/NAD-linked reductase, dimerisation domain; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; FAD/NAD(P)-binding domain; \"\r"]
["P00403","Cytochrome c oxidase subunit 2 OS=Homo sapiens OX=9606 GN=MT-CO2","MT-CO2",25.565,51.669,27.8,5,11,5,1.051,1.08,1.047,0.964,0.955,0.935,0.898,0.00128,"plasma membrane\r","GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0065008 regulation of biological quality; GO:0006123 mitochondrial electron transport, cytochrome c to oxygen; GO:0048732 gland development; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0006753 nucleoside phosphate metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0032502 developmental process; GO:0007595 lactation; GO:0098655 cation transmembrane transport; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0006119 oxidative phosphorylation; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:0048513 animal organ development; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0022900 electron transport chain; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0048856 anatomical structure development; GO:0098662 inorganic cation transmembrane transport; GO:0044707 single-multicellular organism process; GO:0016310 phosphorylation; GO:0034220 ion transmembrane transport; GO:0006725 cellular aromatic compound metabolic process; GO:0042773 ATP synthesis coupled electron transport; GO:0009628 response to abiotic stimulus; GO:0009259 ribonucleotide metabolic process; GO:0022904 respiratory electron transport chain; GO:0050896 response to stimulus; GO:0030879 mammary gland development; GO:0071704 organic substance metabolic process; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0006812 cation transport; GO:0006139 nucleobase-containing compound metabolic process; GO:0009266 response to temperature stimulus; GO:1902600 hydrogen ion transmembrane transport; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009119 ribonucleoside metabolic process; GO:0009987 cellular process; GO:0046034 ATP metabolic process; GO:0007589 body fluid secretion; GO:0050878 regulation of body fluid levels; GO:0006950 response to stress; GO:0098660 inorganic ion transmembrane transport; GO:0048731 system development; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0045333 cellular respiration; GO:0015992 proton transport; GO:0006818 hydrogen transport; GO:0006163 purine nucleotide metabolic process; GO:0055085 transmembrane transport; GO:0046128 purine ribonucleoside metabolic process; GO:0009409 response to cold; GO:0006793 phosphorus metabolic process; GO:0006811 ion transport; GO:0044767 single-organism developmental process; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0051179 localization; GO:0015672 monovalent inorganic cation transport; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:1901564 organonitrogen compound metabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0019866 organelle inner membrane; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0098803 respiratory chain complex; GO:0005751 mitochondrial respiratory chain complex IV; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0070069 cytochrome complex; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005746 mitochondrial respiratory chain; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0045277 respiratory chain complex IV; GO:0031975 envelope; GO:0043234 protein complex; GO:0031966 mitochondrial membrane; GO:0043230 extracellular organelle; GO:0070469 respiratory chain; GO:0044444 cytoplasmic part; ","GO:0015075 ion transmembrane transporter activity; GO:0043167 ion binding; GO:0022892 substrate-specific transporter activity; GO:0015077 monovalent inorganic cation transmembrane transporter activity; GO:0005515 protein binding; GO:0016676 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor; GO:0005507 copper ion binding; GO:0016675 oxidoreductase activity, acting on a heme group of donors; GO:0015002 heme-copper terminal oxidase activity; GO:0015078 hydrogen ion transmembrane transporter activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0016491 oxidoreductase activity; GO:0009055 electron carrier activity; GO:0004129 cytochrome-c oxidase activity; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0022890 inorganic cation transmembrane transporter activity; GO:0008324 cation transmembrane transporter activity; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; ","K02261","COX2; cytochrome c oxidase subunit 2","hsa04260 Cardiac muscle contraction - Homo sapiens (human); hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); ","IPR002429; IPR034210; IPR008972; IPR014222; IPR011759; ","\"Cytochrome c oxidase subunit II-like C-terminal; Cytochrome c oxidase subunit 2, C-terminal; Cupredoxin; Cytochrome c oxidase, subunit II; Cytochrome C oxidase subunit II, transmembrane domain; \"\r"]
["P00441","Superoxide dismutase [Cu-Zn] OS=Homo sapiens OX=9606 GN=SOD1","SOD1",15.936,113.41,80.5,10,18,10,1.077,0.987,1.056,0.93,0.969,0.976,0.921,0.0556,"cytoplasm\r",{"$cut":{"chars":18705,"head":"GO:0044700 single organism signaling; GO:0002694 regulation of leukocyte activation; GO:0010941 regulation of cell death; GO:0048732 gland development; GO:0007272 ensheathment of neurons; GO:0022414 reproductive process; GO:0097332 response to antipsychotic drug; GO:0043523 regulation of neuron apoptotic process; GO:0046683 response to organophosphorus; GO:0044237 cellular metabolic process; GO:0014044 Schwann cell development; GO:0035315 hair cell differentiation; GO:0019430 removal of superoxide radicals; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0009913 epidermal cell differentiation; GO:0008152 metabolic process; GO:0044093 positive regulation of molecular function; GO:0044706 multi-multicellular organism process; GO:0055065 metal ion homeostasis; GO:0008544 epidermis development; GO:0044057 regulation of system process; GO:0090181 regulation of cholesterol metabolic process; GO:0098869 cellular oxidant detoxification; GO:0009790 embryo development; GO:0007422 peripheral nervous system development; GO:0008089 anterograde axonal transport; GO:0048598 embryonic morphogenesis; GO:0090596 sensory organ morphogenesis; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0002064 epithelial cell development; GO:0040014 regulation of multicellular organism growth; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0032287 peripheral nervous system myelin maintenance; GO:0044763 single-organism cellular process; GO:0002520 immune system development; GO:0051704 multi-organism process; GO:0035296 regulation of tube diameter; GO:0006810 transport; GO:0010243 response to organonitrogen compound; GO:0042063 gliogenesis; GO:0080135 regulation of cellular response to stress; GO:0046890 regulation of lipid biosynthetic process; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0048609 multicellular organismal reproductive process; GO:0060548 negative regulation of cell death; GO:0050665 hydrogen peroxide biosynthetic process; GO:0030855 epithelial cell differentiation; GO:0000003 reproduction; GO:0044707 single-multicellular organism process; GO:0045580 regulation of T cell differentiation; GO:0050880 regulation of blood vessel size; GO:0001819 positive regulation of cytokine production; GO:1901700 response to oxygen-containing compound; GO:0002576 platelet degranulation; GO:0003018 vascular process in circulatory system; GO:0048519 negative regulation of biological process; GO:0035865 cellular response to potassium ion; GO:0030705 cytoskeleton-dependent intracellular transport; GO:1903706 regulation of hemopoiesis; GO:0046545 development of primary female sexual characteristics; GO:0009653 anatomical structure morphogenesis; GO:0042493 response to drug; GO:1902884 positive regulation of response to oxidative stress; GO:0042743 hydrogen peroxide metabolic process; GO:1990748 cellular detoxification; GO:0043524 negative regulation of neuron apoptotic process; GO:0009889 regulation of biosynthetic process; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:1902580 single-organism cellular localization; GO:0061458 reproductive system development; GO:0035150 regulation of tube size; GO:0048878 chemical homeostasis; GO:1901215 negative regulation of neuron death; GO:0060088 auditory receptor cell stereocilium organization; GO:1903409 reactive oxygen species biosynthetic process; GO:0045104 intermediate filament cytoskeleton organization; GO:0006950 response to stress; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0048839 inner ear development; GO:0060117 auditory receptor cell development; GO:0009890 negative regulation of biosynthetic process; GO:0045055 regulated exocytosis; GO:0042542 response to hydrogen peroxide; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0045541 negative regulation of cholesterol biosynthetic process; GO:0007423 sensory organ development; GO:0032930 positive regulation of superoxid"}},"GO:0030425 dendrite; GO:0044421 extracellular region part; GO:0099568 cytoplasmic region; GO:0005737 cytoplasm; GO:0032838 cell projection cytoplasm; GO:0043025 neuronal cell body; GO:0032991 macromolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0032839 dendrite cytoplasm; GO:0043209 myelin sheath; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0005759 mitochondrial matrix; GO:0042995 cell projection; GO:0031967 organelle envelope; GO:0031981 nuclear lumen; GO:0005576 extracellular region; GO:0033267 axon part; GO:0005739 mitochondrion; GO:0030424 axon; GO:0031012 extracellular matrix; GO:0043231 intracellular membrane-bounded organelle; GO:1904115 axon cytoplasm; GO:0005758 mitochondrial intermembrane space; GO:0031975 envelope; GO:0005773 vacuole; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0005615 extracellular space; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0031974 membrane-enclosed lumen; GO:0005740 mitochondrial envelope; GO:0070013 intracellular organelle lumen; GO:0031970 organelle envelope lumen; GO:0044464 cell part; GO:0042579 microbody; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0044429 mitochondrial part; GO:0005777 peroxisome; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044463 cell projection part; GO:0005829 cytosol; GO:0031045 dense core granule; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0005634 nucleus; GO:0044297 cell body; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0004784 superoxide dismutase activity; GO:0031267 small GTPase binding; GO:0017048 Rho GTPase binding; GO:0048365 Rac GTPase binding; GO:0019903 protein phosphatase binding; GO:0016721 oxidoreductase activity, acting on superoxide radicals as acceptor; GO:0051087 chaperone binding; GO:0043167 ion binding; GO:0046983 protein dimerization activity; GO:0016209 antioxidant activity; GO:0005515 protein binding; GO:0005507 copper ion binding; GO:0008270 zinc ion binding; GO:0016491 oxidoreductase activity; GO:0042802 identical protein binding; GO:0046914 transition metal ion binding; GO:0017016 Ras GTPase binding; GO:0003824 catalytic activity; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0019902 phosphatase binding; GO:0030346 protein phosphatase 2B binding; GO:0051020 GTPase binding; GO:0019899 enzyme binding; ","K04565","SOD1; superoxide dismutase, Cu-Zn family [EC:1.15.1.1]","hsa05016 Huntington's disease - Homo sapiens (human); hsa04213 Longevity regulating pathway - multiple species - Homo sapiens (human); hsa05014 Amyotrophic lateral sclerosis (ALS) - Homo sapiens (human); hsa05020 Prion diseases - Homo sapiens (human); hsa04146 Peroxisome - Homo sapiens (human); ","IPR001424; ","\"Superoxide dismutase, copper/zinc binding domain; \"\r"]
["P00450","Ceruloplasmin OS=Homo sapiens OX=9606 GN=CP","CP",122.2,323.31,29.4,29,67,29,1.008,1.01,0.987,0.991,1.003,1.007,0.999,0.89,"endoplasmic reticulum\r","GO:0006879 cellular iron ion homeostasis; GO:0065008 regulation of biological quality; GO:0055076 transition metal ion homeostasis; GO:0030001 metal ion transport; GO:0030003 cellular cation homeostasis; GO:0055072 iron ion homeostasis; GO:0044699 single-organism process; GO:0055082 cellular chemical homeostasis; GO:0051234 establishment of localization; GO:0000041 transition metal ion transport; GO:0042592 homeostatic process; GO:0008152 metabolic process; GO:0006812 cation transport; GO:0055080 cation homeostasis; GO:0055065 metal ion homeostasis; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0050801 ion homeostasis; GO:0055114 oxidation-reduction process; GO:0006825 copper ion transport; GO:0044763 single-organism cellular process; GO:0098771 inorganic ion homeostasis; GO:0019725 cellular homeostasis; GO:0046916 cellular transition metal ion homeostasis; GO:0006810 transport; GO:0006873 cellular ion homeostasis; GO:0044710 single-organism metabolic process; GO:0006811 ion transport; GO:0006875 cellular metal ion homeostasis; GO:0051179 localization; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0098588 bounding membrane of organelle; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0098852 lytic vacuole membrane; GO:0005765 lysosomal membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0072562 blood microparticle; GO:0005622 intracellular; GO:0044464 cell part; GO:0044437 vacuolar part; GO:0098805 whole membrane; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0000323 lytic vacuole; ","GO:0016722 oxidoreductase activity, oxidizing metal ions; GO:0046914 transition metal ion binding; GO:0016724 oxidoreductase activity, oxidizing metal ions, oxygen as acceptor; GO:0003824 catalytic activity; GO:0051087 chaperone binding; GO:0005488 binding; GO:0043167 ion binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0005507 copper ion binding; GO:0004322 ferroxidase activity; GO:0016491 oxidoreductase activity; ","K13624","CP; ceruloplasmin [EC:1.16.3.1]","hsa04216 Ferroptosis - Homo sapiens (human); hsa00860 Porphyrin and chlorophyll metabolism - Homo sapiens (human); ","IPR011707; IPR011706; IPR008972; IPR001117; ","\"Multicopper oxidase, type 3; Multicopper oxidase, type 2; Cupredoxin; Multicopper oxidase, type 1; \"\r"]
["P00488","Coagulation factor XIII A chain OS=Homo sapiens OX=9606 GN=F13A1","F13A1",83.266,233.88,32.9,23,61,23,1.041,1.034,1.04,0.994,0.974,0.965,0.942,0.00258,"cytoplasm\r","GO:0044707 single-multicellular organism process; GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0018149 peptide cross-linking; GO:0044267 cellular protein metabolic process; GO:0002576 platelet degranulation; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0007599 hemostasis; GO:0051234 establishment of localization; GO:0071704 organic substance metabolic process; GO:0009611 response to wounding; GO:0008152 metabolic process; GO:1902578 single-organism localization; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0009987 cellular process; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0050878 regulation of body fluid levels; GO:0006950 response to stress; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0072376 protein activation cascade; GO:0044238 primary metabolic process; GO:0072378 blood coagulation, fibrin clot formation; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:0045055 regulated exocytosis; GO:0042060 wound healing; GO:0032940 secretion by cell; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0050817 coagulation; GO:0051179 localization; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:0006887 exocytosis; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0044421 extracellular region part; GO:0005615 extracellular space; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0043226 organelle; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0072562 blood microparticle; GO:0060205 cytoplasmic vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0031093 platelet alpha granule lumen; GO:0030141 secretory granule; GO:0031091 platelet alpha granule; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0016746 transferase activity, transferring acyl groups; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0016740 transferase activity; GO:0003810 protein-glutamine gamma-glutamyltransferase activity; GO:0016755 transferase activity, transferring amino-acyl groups; ","K03917","F13A1; coagulation factor XIII A1 polypeptide [EC:2.3.2.13]","hsa04610 Complement and coagulation cascades - Homo sapiens (human); ","IPR008958; IPR013783; IPR002931; IPR014756; IPR001102; ","\"Transglutaminase, C-terminal; Immunoglobulin-like fold; Transglutaminase-like; Immunoglobulin E-set; Transglutaminase, N-terminal; \"\r"]
["P00491","Purine nucleoside phosphorylase OS=Homo sapiens OX=9606 GN=PNP","PNP",32.118,59.308,42.2,10,15,10,0.841,0.834,0.837,1.108,1.143,1.161,1.358,2.28e-05,"cytoplasm\r","GO:0002694 regulation of leukocyte activation; GO:0009116 nucleoside metabolic process; GO:0045321 leukocyte activation; GO:0019362 pyridine nucleotide metabolic process; GO:0032944 regulation of mononuclear cell proliferation; GO:0034418 urate biosynthetic process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0072525 pyridine-containing compound biosynthetic process; GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway; GO:0008152 metabolic process; GO:0032946 positive regulation of mononuclear cell proliferation; GO:0051240 positive regulation of multicellular organismal process; GO:0006195 purine nucleotide catabolic process; GO:0046130 purine ribonucleoside catabolic process; GO:0009306 protein secretion; GO:0009108 coenzyme biosynthetic process; GO:0045621 positive regulation of lymphocyte differentiation; GO:0008104 protein localization; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0006738 nicotinamide riboside catabolic process; GO:0002443 leukocyte mediated immunity; GO:0018130 heterocycle biosynthetic process; GO:0009166 nucleotide catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0072521 purine-containing compound metabolic process; GO:0006732 coenzyme metabolic process; GO:0019359 nicotinamide nucleotide biosynthetic process; GO:0050670 regulation of lymphocyte proliferation; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:0090407 organophosphate biosynthetic process; GO:0019439 aromatic compound catabolic process; GO:1901575 organic substance catabolic process; GO:0006152 purine nucleoside catabolic process; GO:0019674 NAD metabolic process; GO:0044710 single-organism metabolic process; GO:0046634 regulation of alpha-beta T cell activation; GO:0002682 regulation of immune system process; GO:0051094 positive regulation of developmental process; GO:1901362 organic cyclic compound biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0002283 neutrophil activation involved in immune response; GO:0042127 regulation of cell proliferation; GO:0045580 regulation of T cell differentiation; GO:0046496 nicotinamide nucleotide metabolic process; GO:0072523 purine-containing compound catabolic process; GO:0051239 regulation of multicellular organismal process; GO:0045597 positive regulation of cell differentiation; GO:0070637 pyridine nucleoside metabolic process; GO:1903706 regulation of hemopoiesis; GO:0044270 cellular nitrogen compound catabolic process; GO:0042493 response to drug; GO:0050867 positive regulation of cell activation; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:0044248 cellular catabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0009119 ribonucleoside metabolic process; GO:0050663 cytokine secretion; GO:0045785 positive regulation of cell adhesion; GO:0044711 single-organism biosynthetic process; GO:0016192 vesicle-mediated transport; GO:1901658 glycosyl compound catabolic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901136 carbohydrate derivative catabolic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0071702 organic substance transport; GO:0002376 immune system process; GO:0045582 positive regulation of T cell differentiation; GO:0044238 primary metabolic process; GO:0002263 cell activation involved in immune response; GO:1903039 positive regulation of leukocyte cell-cell adhesion; GO:1901576 organic substance biosynthetic process; GO:0032623 interleukin-2 production; GO:0006163 purine nucleotide metabolic process; GO:0030155 regulation of cell adhesion; GO:0009435 NAD biosynthetic process; GO:0045184 establishment of protein localization; GO:0002696 positive regulation of leukocyte activation; GO:0045055 regulated exocytosis; GO:0006793 phosphorus metabolic process; GO:0001816 cytokine production; GO:0050870 positive regulation of T cell activation; GO:0046495 nicotinamide riboside metabolic process; GO:0044283 small molecule biosynthetic process; GO:0001775 cell activation; GO:0019637 organophosphate metabolic process; GO:0051179 localization; GO:0006955 immune response; GO:0009164 nucleoside catabolic process; GO:0050793 regulation of developmental process; GO:0006887 exocytosis; GO:1901564 organonitrogen compound metabolic process; GO:0008284 positive regulation of cell proliferation; GO:0050863 regulation of T cell activation; GO:0051188 cofactor biosynthetic process; GO:0042278 purine nucleoside metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0019363 pyridine nucleotide biosynthetic process; GO:0051249 regulation of lymphocyte activation; GO:0072524 pyridine-containing compound metabolic process; GO:0046635 positive regulation of alpha-beta T cell activation; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:1902107 positive regulation of leukocyte differentiation; GO:0050671 positive regulation of lymphocyte proliferation; GO:1901292 nucleoside phosphate catabolic process; GO:0046102 inosine metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0070663 regulation of leukocyte proliferation; GO:1901361 organic cyclic compound catabolic process; GO:0033036 macromolecule localization; GO:0002274 myeloid leukocyte activation; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0002446 neutrophil mediated immunity; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0051251 positive regulation of lymphocyte activation; GO:0072526 pyridine-containing compound catabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0051186 cofactor metabolic process; GO:0050865 regulation of cell activation; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0070970 interleukin-2 secretion; GO:0043094 cellular metabolic compound salvage; GO:0032940 secretion by cell; GO:0072522 purine-containing compound biosynthetic process; GO:1902105 regulation of leukocyte differentiation; GO:0043299 leukocyte degranulation; GO:1901657 glycosyl compound metabolic process; GO:0006082 organic acid metabolic process; GO:2000026 regulation of multicellular organismal development; GO:0009165 nucleotide biosynthetic process; GO:0042102 positive regulation of T cell proliferation; GO:0006725 cellular aromatic compound metabolic process; GO:0046434 organophosphate catabolic process; GO:0002252 immune effector process; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:0046415 urate metabolic process; GO:0071704 organic substance metabolic process; GO:0042454 ribonucleoside catabolic process; GO:0006148 inosine catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0036230 granulocyte activation; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:1903708 positive regulation of hemopoiesis; GO:0046637 regulation of alpha-beta T cell differentiation; GO:0022409 positive regulation of cell-cell adhesion; GO:0044712 single-organism catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0042129 regulation of T cell proliferation; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0022407 regulation of cell-cell adhesion; GO:0045619 regulation of lymphocyte differentiation; GO:0002366 leukocyte activation involved in immune response; GO:0046128 purine ribonucleoside metabolic process; GO:0042119 neutrophil activation; GO:0070665 positive regulation of leukocyte proliferation; GO:1901565 organonitrogen compound catabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0046638 positive regulation of alpha-beta T cell differentiation; GO:0002684 positive regulation of immune system process; GO:0070638 pyridine nucleoside catabolic process; GO:0043101 purine-containing compound salvage; GO:0009056 catabolic process; GO:0065007 biological regulation; GO:0046700 heterocycle catabolic process; ","GO:0034774 secretory granule lumen; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016763 transferase activity, transferring pentosyl groups; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0042301 phosphate ion binding; GO:0004731 purine-nucleoside phosphorylase activity; GO:0008144 drug binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0002054 nucleobase binding; GO:0097367 carbohydrate derivative binding; GO:0002060 purine nucleobase binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016757 transferase activity, transferring glycosyl groups; GO:0043168 anion binding; GO:0016740 transferase activity; GO:0036094 small molecule binding; ","K03783","punA; purine-nucleoside phosphorylase [EC:2.4.2.1]","hsa00760 Nicotinate and nicotinamide metabolism - Homo sapiens (human); hsa00230 Purine metabolism - Homo sapiens (human); hsa00240 Pyrimidine metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR000845; ","Nucleoside phosphorylase domain; \r"]
["P00492","Hypoxanthine-guanine phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=HPRT1","HPRT1",24.579,36.601,42.2,8,15,8,0.906,0.934,1.01,1.128,1.064,1,1.12,0.0758,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0046083 adenine metabolic process; GO:0009116 nucleoside metabolic process; GO:0045321 leukocyte activation; GO:0007420 brain development; GO:0032989 cellular component morphogenesis; GO:0009163 nucleoside biosynthetic process; GO:0046129 purine ribonucleoside biosynthetic process; GO:0043174 nucleoside salvage; GO:0007625 grooming behavior; GO:0044237 cellular metabolic process; GO:0021537 telencephalon development; GO:0007610 behavior; GO:0046390 ribose phosphate biosynthetic process; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0006195 purine nucleotide catabolic process; GO:1901068 guanosine-containing compound metabolic process; GO:0046130 purine ribonucleoside catabolic process; GO:0065003 macromolecular complex assembly; GO:0046112 nucleobase biosynthetic process; GO:0009719 response to endogenous stimulus; GO:0019693 ribose phosphate metabolic process; GO:0046099 guanine biosynthetic process; GO:0007399 nervous system development; GO:0046101 hypoxanthine biosynthetic process; GO:0042069 regulation of catecholamine metabolic process; GO:0018130 heterocycle biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0009166 nucleotide catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0072521 purine-containing compound metabolic process; GO:0048812 neuron projection morphogenesis; GO:0009712 catechol-containing compound metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0009168 purine ribonucleoside monophosphate biosynthetic process; GO:0000902 cell morphogenesis; GO:0090407 organophosphate biosynthetic process; GO:0019439 aromatic compound catabolic process; GO:1901575 organic substance catabolic process; GO:0010243 response to organonitrogen compound; GO:0048513 animal organ development; GO:0006152 purine nucleoside catabolic process; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0018958 phenol-containing compound metabolic process; GO:0007417 central nervous system development; GO:0044710 single-organism metabolic process; GO:1901698 response to nitrogen compound; GO:0009112 nucleobase metabolic process; GO:0009126 purine nucleoside monophosphate metabolic process; GO:0006164 purine nucleotide biosynthetic process; GO:0044708 single-organism behavior; GO:1901362 organic cyclic compound biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0019835 cytolysis; GO:1901615 organic hydroxy compound metabolic process; GO:0043103 hypoxanthine salvage; GO:0051260 protein homooligomerization; GO:0009259 ribonucleotide metabolic process; GO:0009169 purine ribonucleoside monophosphate catabolic process; GO:0097164 ammonium ion metabolic process; GO:0072523 purine-containing compound catabolic process; GO:0021953 central nervous system neuron differentiation; GO:0051259 protein oligomerization; GO:0009653 anatomical structure morphogenesis; GO:0044270 cellular nitrogen compound catabolic process; GO:0032264 IMP salvage; GO:0009128 purine nucleoside monophosphate catabolic process; GO:0046483 heterocycle metabolic process; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0044248 cellular catabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0030900 forebrain development; GO:0034655 nucleobase-containing compound catabolic process; GO:0007275 multicellular organism development; GO:0009119 ribonucleoside metabolic process; GO:0006461 protein complex assembly; GO:0044711 single-organism biosynthetic process; GO:0048731 system development; GO:1901658 glycosyl compound catabolic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901136 carbohydrate derivative catabolic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0002376 immune system process; GO:0008283 cell proliferation; GO:0010033 response to organic substance; GO:0042455 ribonucleoside biosynthetic process; GO:0006144 purine nucleobase metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0006163 purine nucleotide metabolic process; GO:0030182 neuron differentiation; GO:0021954 central nervous system neuron development; GO:0006793 phosphorus metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0009260 ribonucleotide biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0001775 cell activation; GO:0009164 nucleoside catabolic process; GO:0021544 subpallium development; GO:1901069 guanosine-containing compound catabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0046148 pigment biosynthetic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0042053 regulation of dopamine metabolic process; GO:0048666 neuron development; GO:0009117 nucleotide metabolic process; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0046098 guanine metabolic process; GO:0009058 biosynthetic process; GO:0046084 adenine biosynthetic process; GO:0045915 positive regulation of catecholamine metabolic process; GO:0009156 ribonucleoside monophosphate biosynthetic process; GO:0046040 IMP metabolic process; GO:0043096 purine nucleobase salvage; GO:0006796 phosphate-containing compound metabolic process; GO:0014075 response to amine; GO:1901292 nucleoside phosphate catabolic process; GO:0009893 positive regulation of metabolic process; GO:0032990 cell part morphogenesis; GO:0051262 protein tetramerization; GO:0022607 cellular component assembly; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0048858 cell projection morphogenesis; GO:1901361 organic cyclic compound catabolic process; GO:0001975 response to amphetamine; GO:0060322 head development; GO:0032943 mononuclear cell proliferation; GO:0032502 developmental process; GO:0046037 GMP metabolic process; GO:0071822 protein complex subunit organization; GO:0009113 purine nucleobase biosynthetic process; GO:0009125 nucleoside monophosphate catabolic process; GO:0033240 positive regulation of cellular amine metabolic process; GO:0009158 ribonucleoside monophosphate catabolic process; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0009154 purine ribonucleotide catabolic process; GO:0006584 catecholamine metabolic process; GO:0042451 purine nucleoside biosynthetic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0030030 cell projection organization; GO:0043094 cellular metabolic compound salvage; GO:0072522 purine-containing compound biosynthetic process; GO:0048813 dendrite morphogenesis; GO:0045964 positive regulation of dopamine metabolic process; GO:0070661 leukocyte proliferation; GO:0019222 regulation of metabolic process; GO:0006168 adenine salvage; GO:0006188 IMP biosynthetic process; GO:1901657 glycosyl compound metabolic process; GO:0070271 protein complex biogenesis; GO:0048856 anatomical structure development; GO:0016043 cellular component organization; GO:0043173 nucleotide salvage; GO:0016358 dendrite development; GO:0009165 nucleotide biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0046434 organophosphate catabolic process; GO:0046651 lymphocyte proliferation; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0000904 cell morphogenesis involved in differentiation; GO:0071704 organic substance metabolic process; GO:0042454 ribonucleoside catabolic process; GO:0046100 hypoxanthine metabolic process; GO:0051289 protein homotetramerization; GO:0030154 cell differentiation; GO:0021895 cerebral cortex neuron differentiation; GO:0034641 cellular nitrogen compound metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0033238 regulation of cellular amine metabolic process; GO:0009124 nucleoside monophosphate biosynthetic process; GO:0006166 purine ribonucleoside salvage; GO:0042440 pigment metabolic process; GO:0044712 single-organism catabolic process; GO:0009127 purine nucleoside monophosphate biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0046649 lymphocyte activation; GO:0032261 purine nucleotide salvage; GO:0042417 dopamine metabolic process; GO:0031175 neuron projection development; GO:0048518 positive regulation of biological process; GO:0009261 ribonucleotide catabolic process; GO:0006178 guanine salvage; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0046128 purine ribonucleoside metabolic process; GO:0046038 GMP catabolic process; GO:1901565 organonitrogen compound catabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0009152 purine ribonucleotide biosynthetic process; GO:1901659 glycosyl compound biosynthetic process; GO:0044767 single-organism developmental process; GO:0007626 locomotory behavior; GO:0009150 purine ribonucleotide metabolic process; GO:0021756 striatum development; GO:0009056 catabolic process; GO:0043101 purine-containing compound salvage; GO:0065007 biological regulation; GO:0046700 heterocycle catabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0005576 extracellular region; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0000287 magnesium ion binding; GO:0016763 transferase activity, transferring pentosyl groups; GO:0052657 guanine phosphoribosyltransferase activity; GO:1901265 nucleoside phosphate binding; GO:0046983 protein dimerization activity; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0004422 hypoxanthine phosphoribosyltransferase activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0016757 transferase activity, transferring glycosyl groups; GO:0016740 transferase activity; GO:0036094 small molecule binding; ","K00760","hprT; hypoxanthine phosphoribosyltransferase [EC:2.4.2.8]","hsa00230 Purine metabolism - Homo sapiens (human); hsa00983 Drug metabolism - other enzymes - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR000836; IPR029057; ","Phosphoribosyltransferase domain; Phosphoribosyltransferase-like; \r"]
["P00505","Aspartate aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=GOT2","GOT2",47.517,119.56,40.2,15,34,15,0.941,0.943,1.031,1.034,1.051,0.998,1.058,0.168,"mitochondria\r","GO:0019550 glutamate catabolic process to aspartate; GO:1901606 alpha-amino acid catabolic process; GO:0019319 hexose biosynthetic process; GO:0019470 4-hydroxyproline catabolic process; GO:0016053 organic acid biosynthetic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:0006006 glucose metabolic process; GO:0008152 metabolic process; GO:0006094 gluconeogenesis; GO:0006520 cellular amino acid metabolic process; GO:0042180 cellular ketone metabolic process; GO:0015718 monocarboxylic acid transport; GO:1901607 alpha-amino acid biosynthetic process; GO:0019471 4-hydroxyproline metabolic process; GO:0006103 2-oxoglutarate metabolic process; GO:0033036 macromolecule localization; GO:0006106 fumarate metabolic process; GO:0044765 single-organism transport; GO:0006869 lipid transport; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0006107 oxaloacetate metabolic process; GO:0005975 carbohydrate metabolic process; GO:0046942 carboxylic acid transport; GO:0006810 transport; GO:0046395 carboxylic acid catabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0043650 dicarboxylic acid biosynthetic process; GO:1901575 organic substance catabolic process; GO:0009068 aspartate family amino acid catabolic process; GO:0046394 carboxylic acid biosynthetic process; GO:0042221 response to chemical; GO:0044710 single-organism metabolic process; GO:0009065 glutamine family amino acid catabolic process; GO:0009063 cellular amino acid catabolic process; GO:0006082 organic acid metabolic process; GO:0043436 oxoacid metabolic process; GO:0043648 dicarboxylic acid metabolic process; GO:0016051 carbohydrate biosynthetic process; GO:0006532 aspartate biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0045471 response to ethanol; GO:0009066 aspartate family amino acid metabolic process; GO:1901700 response to oxygen-containing compound; GO:0046364 monosaccharide biosynthetic process; GO:0006538 glutamate catabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0015908 fatty acid transport; GO:0043649 dicarboxylic acid catabolic process; GO:1902578 single-organism localization; GO:0006575 cellular modified amino acid metabolic process; GO:0005996 monosaccharide metabolic process; GO:0006536 glutamate metabolic process; GO:0044248 cellular catabolic process; GO:0009987 cellular process; GO:0009064 glutamine family amino acid metabolic process; GO:0009067 aspartate family amino acid biosynthetic process; GO:0008652 cellular amino acid biosynthetic process; GO:0042537 benzene-containing compound metabolic process; GO:0044711 single-organism biosynthetic process; GO:0044712 single-organism catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0097052 L-kynurenine metabolic process; GO:0044282 small molecule catabolic process; GO:0097305 response to alcohol; GO:0010876 lipid localization; GO:0071702 organic substance transport; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901605 alpha-amino acid metabolic process; GO:1901576 organic substance biosynthetic process; GO:0015849 organic acid transport; GO:0044249 cellular biosynthetic process; GO:0006820 anion transport; GO:0015711 organic anion transport; GO:0006531 aspartate metabolic process; GO:1901565 organonitrogen compound catabolic process; GO:0042219 cellular modified amino acid catabolic process; GO:0019551 glutamate catabolic process to 2-oxoglutarate; GO:0070189 kynurenine metabolic process; GO:0006811 ion transport; GO:0006533 aspartate catabolic process; GO:0016054 organic acid catabolic process; GO:0019752 carboxylic acid metabolic process; GO:0044283 small molecule biosynthetic process; GO:0051179 localization; GO:0009056 catabolic process; GO:0019318 hexose metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0043025 neuronal cell body; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0005740 mitochondrial envelope; GO:0070062 extracellular exosome; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0043209 myelin sheath; GO:0019866 organelle inner membrane; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0005743 mitochondrial inner membrane; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005759 mitochondrial matrix; GO:0044429 mitochondrial part; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0036477 somatodendritic compartment; GO:0031975 envelope; GO:0043204 perikaryon; GO:0009986 cell surface; GO:0044297 cell body; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0003723 RNA binding; GO:0016769 transferase activity, transferring nitrogenous groups; GO:0016597 amino acid binding; GO:0046983 protein dimerization activity; GO:0043167 ion binding; GO:0043177 organic acid binding; GO:0005515 protein binding; GO:0048037 cofactor binding; GO:0030170 pyridoxal phosphate binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0042802 identical protein binding; GO:0031406 carboxylic acid binding; GO:0016212 kynurenine-oxoglutarate transaminase activity; GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity; GO:0003824 catalytic activity; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0005543 phospholipid binding; GO:0003676 nucleic acid binding; GO:0008289 lipid binding; GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity; GO:0043168 anion binding; GO:0036137 kynurenine aminotransferase activity; GO:0070546 L-phenylalanine aminotransferase activity; GO:0008483 transaminase activity; GO:0016740 transferase activity; GO:0019899 enzyme binding; GO:0036094 small molecule binding; ","K14455","GOT2; aspartate aminotransferase, mitochondrial [EC:2.6.1.1]","hsa01210 2-Oxocarboxylic acid metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00270 Cysteine and methionine metabolism - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); hsa00330 Arginine and proline metabolism - Homo sapiens (human); hsa00220 Arginine biosynthesis - Homo sapiens (human); hsa04975 Fat digestion and absorption - Homo sapiens (human); hsa00400 Phenylalanine, tyrosine and tryptophan biosynthesis - Homo sapiens (human); hsa00360 Phenylalanine metabolism - Homo sapiens (human); hsa00350 Tyrosine metabolism - Homo sapiens (human); hsa01230 Biosynthesis of amino acids - Homo sapiens (human); hsa00250 Alanine, aspartate and glutamate metabolism - Homo sapiens (human); ","IPR004839; IPR015424; IPR015421; ","\"Aminotransferase, class I/classII; Pyridoxal phosphate-dependent transferase; Pyridoxal phosphate-dependent transferase, major region, subdomain 1; \"\r"]
["P00533","Epidermal growth factor receptor OS=Homo sapiens OX=9606 GN=EGFR","EGFR",134.28,98.573,16.2,16,18,16,1.002,0.952,1.092,0.997,0.984,1.034,0.99,0.846,"extracellular\r",{"$cut":{"chars":27013,"head":"GO:0044700 single organism signaling; GO:0048732 gland development; GO:0022414 reproductive process; GO:0010608 posttranscriptional regulation of gene expression; GO:1901185 negative regulation of ERBB signaling pathway; GO:0071384 cellular response to corticosteroid stimulus; GO:0018212 peptidyl-tyrosine modification; GO:0044255 cellular lipid metabolic process; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0001558 regulation of cell growth; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0071549 cellular response to dexamethasone stimulus; GO:0055065 metal ion homeostasis; GO:0044057 regulation of system process; GO:0008544 epidermis development; GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA; GO:0009790 embryo development; GO:1900274 regulation of phospholipase C activity; GO:0043588 skin development; GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity; GO:0051054 positive regulation of DNA metabolic process; GO:0080090 regulation of primary metabolic process; GO:0060148 positive regulation of posttranscriptional gene silencing; GO:0048870 cell motility; GO:0035296 regulation of tube diameter; GO:1900019 regulation of protein kinase C activity; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0060548 negative regulation of cell death; GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity; GO:0071392 cellular response to estradiol stimulus; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0002009 morphogenesis of an epithelium; GO:0044707 single-multicellular organism process; GO:0016310 phosphorylation; GO:0042303 molting cycle; GO:0090277 positive regulation of peptide hormone secretion; GO:0009653 anatomical structure morphogenesis; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0071229 cellular response to acid chemical; GO:0009889 regulation of biosynthetic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0035150 regulation of tube size; GO:0061458 reproductive system development; GO:0048015 phosphatidylinositol-mediated signaling; GO:0048878 chemical homeostasis; GO:0023014 signal transduction by protein phosphorylation; GO:0009416 response to light stimulus; GO:0048546 digestive tract morphogenesis; GO:0050804 modulation of synaptic transmission; GO:0008283 cell proliferation; GO:0032101 regulation of response to external stimulus; GO:0010033 response to organic substance; GO:0042633 hair cycle; GO:1900182 positive regulation of protein localization to nucleus; GO:0001889 liver development; GO:0006644 phospholipid metabolic process; GO:0043412 macromolecule modification; GO:0008284 positive regulation of cell proliferation; GO:0031100 animal organ regeneration; GO:2000045 regulation of G1/S transition of mitotic cell cycle; GO:0032930 positive regulation of superoxide anion generation; GO:0051093 negative regulation of developmental process; GO:0070920 regulation of production of small RNA involved in gene silencing by RNA; GO:0048869 cellular developmental process; GO:0048666 neuron development; GO:0051046 regulation of secretion; GO:0071383 cellular response to steroid hormone stimulus; GO:0006796 phosphate-containing compound metabolic process; GO:0009611 response to wounding; GO:0097746 regulation of blood vessel diameter; GO:0048017 inositol lipid-mediated signaling; GO:0045930 negative regulation of mitotic cell cycle; GO:0016337 single organismal cell-cell adhesion; GO:0048729 tissue morphogenesis; GO:0007165 signal transduction; GO:0032990 cell part morphogenesis; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:1902806 regulation of cell cycle G1/S phase transition; GO:0046777 protein autophosphorylation; GO:0048858 cell projection morphogenesis; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0033036 macromolecule localization; GO:0051726 regulat"}},"GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0098857 membrane microdomain; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0031965 nuclear membrane; GO:0005925 focal adhesion; GO:0098590 plasma membrane region; GO:0030136 clathrin-coated vesicle; GO:0005622 intracellular; GO:0098589 membrane region; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005771 multivesicular body; GO:0005789 endoplasmic reticulum membrane; GO:0045177 apical part of cell; GO:0043233 organelle lumen; GO:0005924 cell-substrate adherens junction; GO:0010008 endosome membrane; GO:0005770 late endosome; GO:0098797 plasma membrane protein complex; GO:0031967 organelle envelope; GO:0043235 receptor complex; GO:0070161 anchoring junction; GO:0012506 vesicle membrane; GO:0044440 endosomal part; GO:0030135 coated vesicle; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0031975 envelope; GO:0043234 protein complex; GO:0016323 basolateral plasma membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0005615 extracellular space; GO:0016324 apical plasma membrane; GO:0031410 cytoplasmic vesicle; GO:0098796 membrane protein complex; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0030662 coated vesicle membrane; GO:0097489 multivesicular body, internal vesicle lumen; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0005912 adherens junction; GO:0044431 Golgi apparatus part; GO:0048471 perinuclear region of cytoplasm; GO:0005768 endosome; GO:0031901 early endosome membrane; GO:0045121 membrane raft; GO:0030139 endocytic vesicle; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0005635 nuclear envelope; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0030665 clathrin-coated vesicle membrane; GO:0016021 integral component of membrane; GO:0045202 synapse; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0044432 endoplasmic reticulum part; GO:0070435 Shc-EGFR complex; GO:0097487 multivesicular body, internal vesicle; GO:0009986 cell surface; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0051015 actin filament binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0019903 protein phosphatase binding; GO:0031625 ubiquitin protein ligase binding; GO:0019838 growth factor binding; GO:0042562 hormone binding; GO:0005085 guanyl-nucleotide exchange factor activity; GO:0005178 integrin binding; GO:0004672 protein kinase activity; GO:0004702 signal transducer, downstream of receptor, with serine/threonine kinase activity; GO:0004871 signal transducer activity; GO:0097159 organic cyclic compound binding; GO:0042802 identical protein binding; GO:0008092 cytoskeletal protein binding; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003677 DNA binding; GO:0005524 ATP binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0005516 calmodulin binding; GO:0004709 MAP kinase kinase kinase activity; GO:0004872 receptor activity; GO:0052813 phosphatidylinositol bisphosphate kinase activity; GO:0003676 nucleic acid binding; GO:0003779 actin binding; GO:0005088 Ras guanyl-nucleotide exchange factor activity; GO:0004674 protein serine/threonine kinase activity; GO:0099600 transmembrane receptor activity; GO:0048408 epidermal growth factor binding; GO:1901265 nucleoside phosphate binding; GO:0005102 receptor binding; GO:0004716 signal transducer, downstream of receptor, with protein tyrosine kinase activity; GO:0003690 double-stranded DNA binding; GO:0046983 protein dimerization activity; GO:0019901 protein kinase binding; GO:0004713 protein tyrosine kinase activity; GO:0005515 protein binding; GO:0003682 chromatin binding; GO:0098772 molecular function regulator; GO:0004888 transmembrane signaling receptor activity; GO:0004714 transmembrane receptor protein tyrosine kinase activity; GO:1901363 heterocyclic compound binding; GO:0016301 kinase activity; GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity; GO:0045296 cadherin binding; GO:0019902 phosphatase binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0038023 signaling receptor activity; GO:0046982 protein heterodimerization activity; GO:0043167 ion binding; GO:0044877 macromolecular complex binding; GO:0019900 kinase binding; GO:0035004 phosphatidylinositol 3-kinase activity; GO:0032549 ribonucleoside binding; GO:0019199 transmembrane receptor protein kinase activity; GO:0050839 cell adhesion molecule binding; GO:0097367 carbohydrate derivative binding; GO:0005057 signal transducer activity, downstream of receptor; GO:0060089 molecular transducer activity; GO:0005006 epidermal growth factor-activated receptor activity; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0001948 glycoprotein binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0019899 enzyme binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0032403 protein complex binding; GO:0036094 small molecule binding; ","K04361","EGFR; epidermal growth factor receptor [EC:2.7.10.1]","hsa04072 Phospholipase D signaling pathway - Homo sapiens (human); hsa04015 Rap1 signaling pathway - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa04014 Ras signaling pathway - Homo sapiens (human); hsa05230 Central carbon metabolism in cancer - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa05206 MicroRNAs in cancer - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa04934 Cushing's syndrome - Homo sapiens (human); hsa05213 Endometrial cancer - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa05224 Breast cancer - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa04520 Adherens junction - Homo sapiens (human); hsa01522 Endocrine resistance - Homo sapiens (human); hsa05215 Prostate cancer - Homo sapiens (human); hsa01521 EGFR tyrosine kinase inhibitor resistance - Homo sapiens (human); hsa05210 Colorectal cancer - Homo sapiens (human); hsa04915 Estrogen signaling pathway - Homo sapiens (human); hsa04630 Jak-STAT signaling pathway - Homo sapiens (human); hsa05120 Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human); hsa04921 Oxytocin signaling pathway - Homo sapiens (human); hsa05231 Choline metabolism in cancer - Homo sapiens (human); hsa05160 Hepatitis C - Homo sapiens (human); hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human); hsa04020 Calcium signaling pathway - Homo sapiens (human); hsa05225 Hepatocellular carcinoma - Homo sapiens (human); hsa04010 MAPK signaling pathway - Homo sapiens (human); hsa04144 Endocytosis - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa05223 Non-small cell lung cancer - Homo sapiens (human); hsa05219 Bladder cancer - Homo sapiens (human); hsa04066 HIF-1 signaling pathway - Homo sapiens (human); hsa04912 GnRH signaling pathway - Homo sapiens (human); hsa04540 Gap junction - Homo sapiens (human); hsa05214 Glioma - Homo sapiens (human); hsa04068 FoxO signaling pathway - Homo sapiens (human); hsa04012 ErbB signaling pathway - Homo sapiens (human); hsa05226 Gastric cancer - Homo sapiens (human); hsa04926 Relaxin signaling pathway - Homo sapiens (human); hsa04928 Parathyroid hormone synthesis, secretion and action - Homo sapiens (human); hsa05218 Melanoma - Homo sapiens (human); hsa05212 Pancreatic cancer - Homo sapiens (human); ","IPR000494; IPR001245; IPR032675; IPR009030; IPR011009; IPR000719; IPR006211; IPR020635; IPR032778; ","\"Receptor L-domain; Serine-threonine/tyrosine-protein kinase catalytic domain; Leucine-rich repeat domain, L domain-like; Growth factor receptor cysteine-rich domain; Protein kinase-like domain; Protein kinase domain; Furin-like cysteine-rich domain; Tyrosine-protein kinase, catalytic domain; Growth factor receptor domain 4; \"\r"]
["P00558","Phosphoglycerate kinase 1 OS=Homo sapiens OX=9606 GN=PGK1","PGK1",44.614,323.31,72.2,29,81,24,0.985,1.006,1.002,0.993,1.022,0.996,1.006,0.623,"cytoplasm\r","GO:0046365 monosaccharide catabolic process; GO:0006757 ATP generation from ADP; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0006165 nucleoside diphosphate phosphorylation; GO:0046031 ADP metabolic process; GO:0019362 pyridine nucleotide metabolic process; GO:0019319 hexose biosynthetic process; GO:0006096 glycolytic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0048869 cellular developmental process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0009185 ribonucleoside diphosphate metabolic process; GO:0046939 nucleotide phosphorylation; GO:0009135 purine nucleoside diphosphate metabolic process; GO:0072524 pyridine-containing compound metabolic process; GO:0044237 cellular metabolic process; GO:0061615 glycolytic process through fructose-6-phosphate; GO:0006796 phosphate-containing compound metabolic process; GO:0006006 glucose metabolic process; GO:0008152 metabolic process; GO:0006094 gluconeogenesis; GO:0006091 generation of precursor metabolites and energy; GO:0006753 nucleoside phosphate metabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0009179 purine ribonucleoside diphosphate metabolic process; GO:0009888 tissue development; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0061620 glycolytic process through glucose-6-phosphate; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0072521 purine-containing compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0006732 coenzyme metabolic process; GO:0005975 carbohydrate metabolic process; GO:0061718 glucose catabolic process to pyruvate; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0016052 carbohydrate catabolic process; GO:0051186 cofactor metabolic process; GO:1901575 organic substance catabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0019674 NAD metabolic process; GO:0044710 single-organism metabolic process; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:0043436 oxoacid metabolic process; GO:0030855 epithelial cell differentiation; GO:0016310 phosphorylation; GO:0016051 carbohydrate biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0046496 nicotinamide nucleotide metabolic process; GO:0009259 ribonucleotide metabolic process; GO:0006734 NADH metabolic process; GO:0046364 monosaccharide biosynthetic process; GO:0006735 NADH regeneration; GO:0071704 organic substance metabolic process; GO:0061621 canonical glycolysis; GO:0030154 cell differentiation; GO:0006090 pyruvate metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0005996 monosaccharide metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0009987 cellular process; GO:0009119 ribonucleoside metabolic process; GO:0009132 nucleoside diphosphate metabolic process; GO:0046034 ATP metabolic process; GO:0044724 single-organism carbohydrate catabolic process; GO:0044711 single-organism biosynthetic process; GO:0044712 single-organism catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044282 small molecule catabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0006163 purine nucleotide metabolic process; GO:0046128 purine ribonucleoside metabolic process; GO:0006007 glucose catabolic process; GO:0006793 phosphorus metabolic process; GO:0044767 single-organism developmental process; GO:0044283 small molecule biosynthetic process; GO:0019752 carboxylic acid metabolic process; GO:0019637 organophosphate metabolic process; GO:0019320 hexose catabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0009056 catabolic process; GO:0019318 hexose metabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0098857 membrane microdomain; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0098589 membrane region; GO:1903561 extracellular vesicle; GO:0045121 membrane raft; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0016774 phosphotransferase activity, carboxyl group as acceptor; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016301 kinase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0004618 phosphoglycerate kinase activity; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0016740 transferase activity; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K00927","PGK; phosphoglycerate kinase [EC:2.7.2.3]","hsa04066 HIF-1 signaling pathway - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human); hsa01230 Biosynthesis of amino acids - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); ","IPR015824; IPR015901; ","\"Phosphoglycerate kinase, N-terminal; Phosphoglycerate kinase, C-terminal; \"\r"]
["P00568","Adenylate kinase isoenzyme 1 OS=Homo sapiens OX=9606 GN=AK1","AK1",21.635,52.218,50.5,10,15,10,1.072,1.079,1.109,0.903,0.898,0.913,0.833,9.51e-05,"cytoplasm\r","GO:0016310 phosphorylation; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0006165 nucleoside diphosphate phosphorylation; GO:0006725 cellular aromatic compound metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0015949 nucleobase-containing small molecule interconversion; GO:0009259 ribonucleotide metabolic process; GO:0009142 nucleoside triphosphate biosynthetic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0046939 nucleotide phosphorylation; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0009987 cellular process; GO:0009119 ribonucleoside metabolic process; GO:0009132 nucleoside diphosphate metabolic process; GO:0046034 ATP metabolic process; GO:0018130 heterocycle biosynthetic process; GO:0044711 single-organism biosynthetic process; GO:0044281 small molecule metabolic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0044763 single-organism cellular process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0044249 cellular biosynthetic process; GO:0006163 purine nucleotide metabolic process; GO:0090407 organophosphate biosynthetic process; GO:0046128 purine ribonucleoside metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0019637 organophosphate metabolic process; GO:0009126 purine nucleoside monophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:1901657 glycosyl compound metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0004017 adenylate kinase activity; GO:0004550 nucleoside diphosphate kinase activity; GO:0019205 nucleobase-containing compound kinase activity; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0000166 nucleotide binding; GO:0019201 nucleotide kinase activity; GO:0016776 phosphotransferase activity, phosphate group as acceptor; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016301 kinase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0016740 transferase activity; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K00939","adk; adenylate kinase [EC:2.7.4.3]","hsa00730 Thiamine metabolism - Homo sapiens (human); hsa00230 Purine metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR027417; ","P-loop containing nucleoside triphosphate hydrolase; \r"]
["P00734","Prothrombin OS=Homo sapiens OX=9606 GN=F2","F2",70.036,254.59,46.1,24,45,24,0.969,0.974,0.992,1.037,1.044,1.017,1.056,0.007,"extracellular\r","GO:0044700 single organism signaling; GO:0014013 regulation of gliogenesis; GO:0009891 positive regulation of biosynthetic process; GO:0044237 cellular metabolic process; GO:0045927 positive regulation of growth; GO:0048710 regulation of astrocyte differentiation; GO:0001558 regulation of cell growth; GO:0042730 fibrinolysis; GO:0008152 metabolic process; GO:0008360 regulation of cell shape; GO:0044093 positive regulation of molecular function; GO:0055065 metal ion homeostasis; GO:0030194 positive regulation of blood coagulation; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0030307 positive regulation of cell growth; GO:0030168 platelet activation; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0048870 cell motility; GO:0006874 cellular calcium ion homeostasis; GO:0006810 transport; GO:0006953 acute-phase response; GO:1900048 positive regulation of hemostasis; GO:0002526 acute inflammatory response; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010721 negative regulation of cell development; GO:0044707 single-multicellular organism process; GO:0010543 regulation of platelet activation; GO:0048519 negative regulation of biological process; GO:0009889 regulation of biosynthetic process; GO:0010959 regulation of metal ion transport; GO:0048878 chemical homeostasis; GO:0051928 positive regulation of calcium ion transport; GO:0018214 protein carboxylation; GO:0045861 negative regulation of proteolysis; GO:0051282 regulation of sequestering of calcium ion; GO:0006950 response to stress; GO:0051917 regulation of fibrinolysis; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0051924 regulation of calcium ion transport; GO:0002376 immune system process; GO:0032101 regulation of response to external stimulus; GO:0072378 blood coagulation, fibrin clot formation; GO:1900182 positive regulation of protein localization to nucleus; GO:0030195 negative regulation of blood coagulation; GO:0061041 regulation of wound healing; GO:1904064 positive regulation of cation transmembrane transport; GO:0031325 positive regulation of cellular metabolic process; GO:0043412 macromolecule modification; GO:1903034 regulation of response to wounding; GO:1903827 regulation of cellular protein localization; GO:0050819 negative regulation of coagulation; GO:0008284 positive regulation of cell proliferation; GO:0051093 negative regulation of developmental process; GO:0051674 localization of cell; GO:0044246 regulation of multicellular organismal metabolic process; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0016485 protein processing; GO:0009611 response to wounding; GO:0007165 signal transduction; GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling; GO:0009893 positive regulation of metabolic process; GO:0032846 positive regulation of homeostatic process; GO:1900046 regulation of hemostasis; GO:0033674 positive regulation of kinase activity; GO:0045937 positive regulation of phosphate metabolic process; GO:0051279 regulation of release of sequestered calcium ion into cytosol; GO:0007597 blood coagulation, intrinsic pathway; GO:0098771 inorganic ion homeostasis; GO:0090280 positive regulation of calcium ion import; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:1903035 negative regulation of response to wounding; GO:0006954 inflammatory response; GO:1900180 regulation of protein localization to nucleus; GO:0065009 regulation of molecular function; GO:0090218 positive regulation of lipid kinase activity; GO:0006952 defense response; GO:0036211 protein modification process; GO:2000377 regulation of reactive oxygen species metabolic process; GO:0043549 regulation of kinase activity; GO:0016477 cell migration; GO:0040008 regulation of growth; GO:2000021 regulation of ion homeostasis; GO:1903829 positive regulation of cellular protein localization; GO:0032967 positive regulation of collagen biosynthetic process; GO:0060255 regulation of macromolecule metabolic process; GO:0048193 Golgi vesicle transport; GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:0051961 negative regulation of nervous system development; GO:0055080 cation homeostasis; GO:0023056 positive regulation of signaling; GO:0034641 cellular nitrogen compound metabolic process; GO:0010647 positive regulation of cell communication; GO:0045595 regulation of cell differentiation; GO:0050878 regulation of body fluid levels; GO:0051049 regulation of transport; GO:0090279 regulation of calcium ion import; GO:0045686 negative regulation of glial cell differentiation; GO:0001932 regulation of protein phosphorylation; GO:0010544 negative regulation of platelet activation; GO:0050820 positive regulation of coagulation; GO:0001934 positive regulation of protein phosphorylation; GO:0043085 positive regulation of catalytic activity; GO:0018193 peptidyl-amino acid modification; GO:0034765 regulation of ion transmembrane transport; GO:0051248 negative regulation of protein metabolic process; GO:0010467 gene expression; GO:0050767 regulation of neurogenesis; GO:0065008 regulation of biological quality; GO:0007596 blood coagulation; GO:0006518 peptide metabolic process; GO:0032270 positive regulation of cellular protein metabolic process; GO:0007166 cell surface receptor signaling pathway; GO:0019216 regulation of lipid metabolic process; GO:1904427 positive regulation of calcium ion transmembrane transport; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0032102 negative regulation of response to external stimulus; GO:0090303 positive regulation of wound healing; GO:0010562 positive regulation of phosphorus metabolic process; GO:0042327 positive regulation of phosphorylation; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0051347 positive regulation of transferase activity; GO:0017187 peptidyl-glutamic acid carboxylation; GO:0007399 nervous system development; GO:0051174 regulation of phosphorus metabolic process; GO:0043269 regulation of ion transport; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0050768 negative regulation of neurogenesis; GO:0034762 regulation of transmembrane transport; GO:0050900 leukocyte migration; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0010604 positive regulation of macromolecule metabolic process; GO:0018200 peptidyl-glutamic acid modification; GO:0006464 cellular protein modification process; GO:0050817 coagulation; GO:1903036 positive regulation of response to wounding; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0034764 positive regulation of transmembrane transport; GO:0042127 regulation of cell proliferation; GO:0031399 regulation of protein modification process; GO:0030193 regulation of blood coagulation; GO:0044267 cellular protein metabolic process; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:0032844 regulation of homeostatic process; GO:0051239 regulation of multicellular organismal process; GO:0060341 regulation of cellular localization; GO:1900047 negative regulation of hemostasis; GO:0050866 negative regulation of cell activation; GO:0014066 regulation of phosphatidylinositol 3-kinase signaling; GO:0051338 regulation of transferase activity; GO:0044253 positive regulation of multicellular organismal metabolic process; GO:0007275 multicellular organism development; GO:0032880 regulation of protein localization; GO:0009966 regulation of signal transduction; GO:1904062 regulation of cation transmembrane transport; GO:1902531 regulation of intracellular signal transduction; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0072376 protein activation cascade; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0045685 regulation of glial cell differentiation; GO:0032965 regulation of collagen biosynthetic process; GO:0043270 positive regulation of ion transport; GO:0051247 positive regulation of protein metabolic process; GO:0006873 cellular ion homeostasis; GO:0001775 cell activation; GO:0006928 movement of cell or subcellular component; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0010712 regulation of collagen metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0043550 regulation of lipid kinase activity; GO:0072503 cellular divalent inorganic cation homeostasis; GO:0006465 signal peptide processing; GO:1902533 positive regulation of intracellular signal transduction; GO:0022008 neurogenesis; GO:0051241 negative regulation of multicellular organismal process; GO:0051234 establishment of localization; GO:0010646 regulation of cell communication; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0032103 positive regulation of response to external stimulus; GO:0045596 negative regulation of cell differentiation; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0050801 ion homeostasis; GO:1900736 regulation of phospholipase C-activating G-protein coupled receptor signaling pathway; GO:0055074 calcium ion homeostasis; GO:0008277 regulation of G-protein coupled receptor protein signaling pathway; GO:0048522 positive regulation of cellular process; GO:0019725 cellular homeostasis; GO:0043603 cellular amide metabolic process; GO:0051050 positive regulation of transport; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0050865 regulation of cell activation; GO:0034767 positive regulation of ion transmembrane transport; GO:0010714 positive regulation of collagen metabolic process; GO:0019222 regulation of metabolic process; GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway; GO:0019220 regulation of phosphate metabolic process; GO:0040011 locomotion; GO:0072507 divalent inorganic cation homeostasis; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0048712 negative regulation of astrocyte differentiation; GO:0051480 regulation of cytosolic calcium ion concentration; GO:0030003 cellular cation homeostasis; GO:0051918 negative regulation of fibrinolysis; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0055082 cellular chemical homeostasis; GO:0007599 hemostasis; GO:1903169 regulation of calcium ion transmembrane transport; GO:0006508 proteolysis; GO:0010524 positive regulation of calcium ion transport into cytosol; GO:0009987 cellular process; GO:0006807 nitrogen compound metabolic process; GO:0031401 positive regulation of protein modification process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0048518 positive regulation of biological process; GO:0061045 negative regulation of wound healing; GO:0045834 positive regulation of lipid metabolic process; GO:0051641 cellular localization; GO:0050818 regulation of coagulation; GO:0014014 negative regulation of gliogenesis; GO:2000379 positive regulation of reactive oxygen species metabolic process; GO:0042060 wound healing; GO:0051281 positive regulation of release of sequestered calcium ion into cytosol; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0010522 regulation of calcium ion transport into cytosol; GO:0006875 cellular metal ion homeostasis; GO:0009967 positive regulation of signal transduction; GO:0051128 regulation of cellular component organization; GO:0051604 protein maturation; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0022604 regulation of cell morphogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005788 endoplasmic reticulum lumen; GO:0043229 intracellular organelle; GO:0005783 endoplasmic reticulum; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0005796 Golgi lumen; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0005886 plasma membrane; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0072562 blood microparticle; GO:0070013 intracellular organelle lumen; GO:0044432 endoplasmic reticulum part; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0005794 Golgi apparatus; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0038023 signaling receptor activity; GO:0008083 growth factor activity; GO:0008233 peptidase activity; GO:0005102 receptor binding; GO:0043167 ion binding; GO:0008236 serine-type peptidase activity; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0004871 signal transducer activity; GO:0004252 serine-type endopeptidase activity; GO:0004175 endopeptidase activity; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0003824 catalytic activity; GO:0017171 serine hydrolase activity; GO:0070053 thrombospondin receptor activity; GO:0005488 binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0005509 calcium ion binding; ","K01313","F2; coagulation factor II (thrombin) [EC:3.4.21.5]","hsa04610 Complement and coagulation cascades - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa04080 Neuroactive ligand-receptor interaction - Homo sapiens (human); ","IPR009003; IPR017857; IPR000294; IPR000001; IPR001254; IPR018992; IPR013806; ","\"Peptidase S1, PA clan; Coagulation factor, subgroup, Gla domain; Gamma-carboxyglutamic acid-rich (GLA) domain; Kringle; Serine proteases, trypsin domain; Thrombin light chain; Kringle-like fold; \"\r"]
["P00736","Complement C1r subcomponent OS=Homo sapiens OX=9606 GN=C1R","C1R",80.118,117.6,25.4,14,26,14,0.996,1.042,1.048,1.025,0.976,1.021,0.979,0.405,"extracellular\r","GO:0016064 immunoglobulin mediated immune response; GO:0002252 immune effector process; GO:0006959 humoral immune response; GO:0050896 response to stimulus; GO:0045087 innate immune response; GO:0019724 B cell mediated immunity; GO:0071704 organic substance metabolic process; GO:0006956 complement activation; GO:0008152 metabolic process; GO:0002250 adaptive immune response; GO:0006958 complement activation, classical pathway; GO:0006508 proteolysis; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0002449 lymphocyte mediated immunity; GO:0050778 positive regulation of immune response; GO:0002253 activation of immune response; GO:0002443 leukocyte mediated immunity; GO:0006950 response to stress; GO:0002376 immune system process; GO:0072376 protein activation cascade; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0050776 regulation of immune response; GO:0050789 regulation of biological process; GO:0048583 regulation of response to stimulus; GO:0002684 positive regulation of immune system process; GO:0002682 regulation of immune system process; GO:0006952 defense response; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0048584 positive regulation of response to stimulus; GO:0006955 immune response; GO:0065007 biological regulation; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0072562 blood microparticle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:0004252 serine-type endopeptidase activity; GO:0004175 endopeptidase activity; GO:0008233 peptidase activity; GO:0003824 catalytic activity; GO:0017171 serine hydrolase activity; GO:0005488 binding; GO:0043167 ion binding; GO:0008236 serine-type peptidase activity; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0005509 calcium ion binding; ","K01330","C1R; complement component 1, r subcomponent [EC:3.4.21.41]","hsa05322 Systemic lupus erythematosus - Homo sapiens (human); hsa05133 Pertussis - Homo sapiens (human); hsa04610 Complement and coagulation cascades - Homo sapiens (human); hsa05150 Staphylococcus aureus infection - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); ","IPR009003; IPR000859; IPR000436; IPR001254; IPR001881; IPR000742; ","\"Peptidase S1, PA clan; CUB domain; Sushi/SCR/CCP domain; Serine proteases, trypsin domain; EGF-like calcium-binding domain; EGF-like domain; \"\r"]
["P00738","Haptoglobin OS=Homo sapiens OX=9606 GN=HP","HP",45.205,304.39,50.7,27,103,11,0.91,0.917,0.901,1.09,1.099,1.108,1.209,1.54e-05,"extracellular\r","GO:0010941 regulation of cell death; GO:0045321 leukocyte activation; GO:0098542 defense response to other organism; GO:0044699 single-organism process; GO:0051234 establishment of localization; GO:0009607 response to biotic stimulus; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0006979 response to oxidative stress; GO:0098869 cellular oxidant detoxification; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0010035 response to inorganic substance; GO:2000296 negative regulation of hydrogen peroxide catabolic process; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0002443 leukocyte mediated immunity; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0009636 response to toxic substance; GO:0000302 response to reactive oxygen species; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0031323 regulation of cellular metabolic process; GO:0043086 negative regulation of catalytic activity; GO:0051341 regulation of oxidoreductase activity; GO:0051704 multi-organism process; GO:0002444 myeloid leukocyte mediated immunity; GO:0010942 positive regulation of cell death; GO:0006810 transport; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0006953 acute-phase response; GO:0050790 regulation of catalytic activity; GO:0002526 acute inflammatory response; GO:0032940 secretion by cell; GO:0006954 inflammatory response; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0043299 leukocyte degranulation; GO:0006952 defense response; GO:2000377 regulation of reactive oxygen species metabolic process; GO:0098754 detoxification; GO:0050794 regulation of cellular process; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:1901700 response to oxygen-containing compound; GO:0010310 regulation of hydrogen peroxide metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0048523 negative regulation of cellular process; GO:0043207 response to external biotic stimulus; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0010727 negative regulation of hydrogen peroxide metabolic process; GO:0071704 organic substance metabolic process; GO:1990748 cellular detoxification; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0051354 negative regulation of oxidoreductase activity; GO:0009895 negative regulation of catabolic process; GO:0006508 proteolysis; GO:2000378 negative regulation of reactive oxygen species metabolic process; GO:0006898 receptor-mediated endocytosis; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0009617 response to bacterium; GO:2000295 regulation of hydrogen peroxide catabolic process; GO:0006950 response to stress; GO:0042742 defense response to bacterium; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0006897 endocytosis; GO:0044238 primary metabolic process; GO:0043312 neutrophil degranulation; GO:0002263 cell activation involved in immune response; GO:0048518 positive regulation of biological process; GO:0009892 negative regulation of metabolic process; GO:0002366 leukocyte activation involved in immune response; GO:0031330 negative regulation of cellular catabolic process; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0042542 response to hydrogen peroxide; GO:0001775 cell activation; GO:0006955 immune response; GO:0051179 localization; GO:0006887 exocytosis; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:1904724 tertiary granule lumen; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0030139 endocytic vesicle; GO:0031838 haptoglobin-hemoglobin complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0070820 tertiary granule; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0043226 organelle; GO:0072562 blood microparticle; GO:0060205 cytoplasmic vesicle lumen; GO:0035580 specific granule lumen; GO:0042581 specific granule; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0071682 endocytic vesicle lumen; ","GO:0004252 serine-type endopeptidase activity; GO:0004175 endopeptidase activity; GO:0008233 peptidase activity; GO:0003824 catalytic activity; GO:0017171 serine hydrolase activity; GO:0005488 binding; GO:0008236 serine-type peptidase activity; GO:0016209 antioxidant activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0030492 hemoglobin binding; GO:0016787 hydrolase activity; GO:0005515 protein binding; ","K16142",null,null,"IPR009003; IPR000436; IPR001254; ","\"Peptidase S1, PA clan; Sushi/SCR/CCP domain; Serine proteases, trypsin domain; \"\r"]
["P00739","Haptoglobin-related protein OS=Homo sapiens OX=9606 GN=HPR","HPR",39.029,31.769,33.9,17,56,1,0.955,0.827,0.87,1.188,1.112,1.045,1.261,0.0143,"mitochondria\r","GO:0006810 transport; GO:0008152 metabolic process; GO:0016192 vesicle-mediated transport; GO:0006508 proteolysis; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0006898 receptor-mediated endocytosis; GO:0051179 localization; GO:0006897 endocytosis; GO:0044238 primary metabolic process; GO:0051234 establishment of localization; GO:0071704 organic substance metabolic process; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0072562 blood microparticle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0032994 protein-lipid complex; GO:0034366 spherical high-density lipoprotein particle; GO:1990777 lipoprotein particle; GO:0034358 plasma lipoprotein particle; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0032991 macromolecular complex; GO:0034364 high-density lipoprotein particle; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:0004252 serine-type endopeptidase activity; GO:0004175 endopeptidase activity; GO:0008233 peptidase activity; GO:0003824 catalytic activity; GO:0017171 serine hydrolase activity; GO:0005488 binding; GO:0008236 serine-type peptidase activity; GO:0030492 hemoglobin binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0005515 protein binding; GO:0016787 hydrolase activity; ","K14477","HPR; haptoglobin-related protein","hsa05143 African trypanosomiasis - Homo sapiens (human); ","IPR009003; IPR000436; IPR001254; ","\"Peptidase S1, PA clan; Sushi/SCR/CCP domain; Serine proteases, trypsin domain; \"\r"]
["P00740","Coagulation factor IX OS=Homo sapiens OX=9606 GN=F9","F9",51.778,38.924,15.8,7,10,7,1.048,1.018,1.056,0.947,0.931,0.979,0.915,0.00866,"extracellular\r","GO:0046907 intracellular transport; GO:0044707 single-multicellular organism process; GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0006518 peptide metabolic process; GO:0007598 blood coagulation, extrinsic pathway; GO:0006465 signal peptide processing; GO:0044267 cellular protein metabolic process; GO:0048193 Golgi vesicle transport; GO:0044699 single-organism process; GO:0016485 protein processing; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0007599 hemostasis; GO:0051234 establishment of localization; GO:0071704 organic substance metabolic process; GO:0009611 response to wounding; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0006508 proteolysis; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009987 cellular process; GO:0031638 zymogen activation; GO:0017187 peptidyl-glutamic acid carboxylation; GO:0018214 protein carboxylation; GO:0050878 regulation of body fluid levels; GO:0006950 response to stress; GO:0007597 blood coagulation, intrinsic pathway; GO:0016192 vesicle-mediated transport; GO:0006807 nitrogen compound metabolic process; GO:0072376 protein activation cascade; GO:0043603 cellular amide metabolic process; GO:0044238 primary metabolic process; GO:0032501 multicellular organismal process; GO:0072378 blood coagulation, fibrin clot formation; GO:0051641 cellular localization; GO:0018193 peptidyl-amino acid modification; GO:0006810 transport; GO:0042060 wound healing; GO:0044260 cellular macromolecule metabolic process; GO:0018200 peptidyl-glutamic acid modification; GO:0006464 cellular protein modification process; GO:0010467 gene expression; GO:0050817 coagulation; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:0051179 localization; GO:0051604 protein maturation; GO:0006888 ER to Golgi vesicle-mediated transport; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005788 endoplasmic reticulum lumen; GO:0044446 intracellular organelle part; GO:0005796 Golgi lumen; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044432 endoplasmic reticulum part; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0004252 serine-type endopeptidase activity; GO:0004175 endopeptidase activity; GO:0008233 peptidase activity; GO:0017171 serine hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0008236 serine-type peptidase activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0005509 calcium ion binding; ","K01321","F9; coagulation factor IX (Christmas factor) [EC:3.4.21.22]","hsa04610 Complement and coagulation cascades - Homo sapiens (human); ","IPR009003; IPR017857; IPR000294; IPR001254; IPR001881; IPR000742; ","\"Peptidase S1, PA clan; Coagulation factor, subgroup, Gla domain; Gamma-carboxyglutamic acid-rich (GLA) domain; Serine proteases, trypsin domain; EGF-like calcium-binding domain; EGF-like domain; \"\r"]
["P00742","Coagulation factor X OS=Homo sapiens OX=9606 GN=F10","F10",54.731,75.661,12.1,4,4,4,1.125,1.055,1.019,0.96,0.921,0.925,0.877,0.0149,"extracellular\r","GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0030335 positive regulation of cell migration; GO:0006518 peptide metabolic process; GO:0051896 regulation of protein kinase B signaling; GO:0007598 blood coagulation, extrinsic pathway; GO:0040017 positive regulation of locomotion; GO:0006465 signal peptide processing; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0016485 protein processing; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:0009611 response to wounding; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0010646 regulation of cell communication; GO:0032879 regulation of localization; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0017187 peptidyl-glutamic acid carboxylation; GO:0007597 blood coagulation, intrinsic pathway; GO:0048522 positive regulation of cellular process; GO:0043603 cellular amide metabolic process; GO:0051272 positive regulation of cellular component movement; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0018200 peptidyl-glutamic acid modification; GO:0006464 cellular protein modification process; GO:0050817 coagulation; GO:0036211 protein modification process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0046907 intracellular transport; GO:0044267 cellular protein metabolic process; GO:0048193 Golgi vesicle transport; GO:2000147 positive regulation of cell motility; GO:0050896 response to stimulus; GO:0007599 hemostasis; GO:0071704 organic substance metabolic process; GO:0023056 positive regulation of signaling; GO:2000145 regulation of cell motility; GO:0034641 cellular nitrogen compound metabolic process; GO:0006508 proteolysis; GO:0010647 positive regulation of cell communication; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:0018214 protein carboxylation; GO:0051897 positive regulation of protein kinase B signaling; GO:0050878 regulation of body fluid levels; GO:1902531 regulation of intracellular signal transduction; GO:0006950 response to stress; GO:0051270 regulation of cellular component movement; GO:0016192 vesicle-mediated transport; GO:0006807 nitrogen compound metabolic process; GO:0030334 regulation of cell migration; GO:0072376 protein activation cascade; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0072378 blood coagulation, fibrin clot formation; GO:0051641 cellular localization; GO:0018193 peptidyl-amino acid modification; GO:0042060 wound healing; GO:0010467 gene expression; GO:0009967 positive regulation of signal transduction; GO:0043412 macromolecule modification; GO:0051179 localization; GO:0040012 regulation of locomotion; GO:0048584 positive regulation of response to stimulus; GO:0051604 protein maturation; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0065007 biological regulation; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0009897 external side of plasma membrane; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0044431 Golgi apparatus part; GO:0043227 membrane-bounded organelle; GO:0031233 intrinsic component of external side of plasma membrane; GO:0043233 organelle lumen; GO:0098552 side of membrane; GO:0043229 intracellular organelle; GO:0005788 endoplasmic reticulum lumen; GO:0031226 intrinsic component of plasma membrane; GO:0044446 intracellular organelle part; GO:0005796 Golgi lumen; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0044432 endoplasmic reticulum part; GO:0009986 cell surface; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:0008233 peptidase activity; GO:0043167 ion binding; GO:0008236 serine-type peptidase activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0004175 endopeptidase activity; GO:0004252 serine-type endopeptidase activity; GO:0003824 catalytic activity; GO:0017171 serine hydrolase activity; GO:0005488 binding; GO:0005543 phospholipid binding; GO:0008289 lipid binding; GO:0043169 cation binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0046872 metal ion binding; GO:0043168 anion binding; GO:0005509 calcium ion binding; ","K01314","F10; coagulation factor X [EC:3.4.21.6]","hsa04610 Complement and coagulation cascades - Homo sapiens (human); ","IPR009003; IPR017857; IPR000294; IPR001254; IPR001881; IPR000742; ","\"Peptidase S1, PA clan; Coagulation factor, subgroup, Gla domain; Gamma-carboxyglutamic acid-rich (GLA) domain; Serine proteases, trypsin domain; EGF-like calcium-binding domain; EGF-like domain; \"\r"]
["P00746","Complement factor D OS=Homo sapiens OX=9606 GN=CFD","CFD",27.033,246.81,53,12,23,12,1.151,1.137,1.156,0.795,0.877,0.857,0.734,0.0005,"extracellular\r","GO:0045321 leukocyte activation; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0044699 single-organism process; GO:0002576 platelet degranulation; GO:0006959 humoral immune response; GO:0050896 response to stimulus; GO:0045087 innate immune response; GO:0071704 organic substance metabolic process; GO:0051234 establishment of localization; GO:0006956 complement activation; GO:0008152 metabolic process; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0006508 proteolysis; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0036230 granulocyte activation; GO:0050778 positive regulation of immune response; GO:0009987 cellular process; GO:0002274 myeloid leukocyte activation; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0002253 activation of immune response; GO:0002443 leukocyte mediated immunity; GO:0006950 response to stress; GO:0016192 vesicle-mediated transport; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0072376 protein activation cascade; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0002263 cell activation involved in immune response; GO:0002444 myeloid leukocyte mediated immunity; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0002366 leukocyte activation involved in immune response; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:0050789 regulation of biological process; GO:0006957 complement activation, alternative pathway; GO:0032940 secretion by cell; GO:0048583 regulation of response to stimulus; GO:0002684 positive regulation of immune system process; GO:0001775 cell activation; GO:0002682 regulation of immune system process; GO:0006952 defense response; GO:0043299 leukocyte degranulation; GO:0048584 positive regulation of response to stimulus; GO:0006955 immune response; GO:0051179 localization; GO:0065007 biological regulation; GO:0006887 exocytosis; ","GO:0034774 secretory granule lumen; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044433 cytoplasmic vesicle part; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0060205 cytoplasmic vesicle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0031093 platelet alpha granule lumen; GO:0030141 secretory granule; GO:0031091 platelet alpha granule; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0004252 serine-type endopeptidase activity; GO:0004175 endopeptidase activity; GO:0008233 peptidase activity; GO:0017171 serine hydrolase activity; GO:0003824 catalytic activity; GO:0008236 serine-type peptidase activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0016787 hydrolase activity; ","K01334","CFD; component factor D [EC:3.4.21.46]","hsa04610 Complement and coagulation cascades - Homo sapiens (human); hsa05150 Staphylococcus aureus infection - Homo sapiens (human); ","IPR009003; IPR001254; ","\"Peptidase S1, PA clan; Serine proteases, trypsin domain; \"\r"]
["P00747","Plasminogen OS=Homo sapiens OX=9606 GN=PLG","PLG",90.568,242.32,43.5,30,49,30,0.965,0.965,0.951,1.049,1.055,1.037,1.09,0.000255,"extracellular\r","GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0008285 negative regulation of cell proliferation; GO:0051234 establishment of localization; GO:0042730 fibrinolysis; GO:0009611 response to wounding; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0032102 negative regulation of response to external stimulus; GO:0032103 positive regulation of response to external stimulus; GO:2000047 regulation of cell-cell adhesion mediated by cadherin; GO:0022617 extracellular matrix disassembly; GO:1900046 regulation of hemostasis; GO:0090303 positive regulation of wound healing; GO:0030198 extracellular matrix organization; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0030194 positive regulation of blood coagulation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0044763 single-organism cellular process; GO:0032501 multicellular organismal process; GO:1903035 negative regulation of response to wounding; GO:0006810 transport; GO:0050789 regulation of biological process; GO:1900048 positive regulation of hemostasis; GO:0032940 secretion by cell; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0050817 coagulation; GO:0010812 negative regulation of cell-substrate adhesion; GO:1903036 positive regulation of response to wounding; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0007162 negative regulation of cell adhesion; GO:0042127 regulation of cell proliferation; GO:0051918 negative regulation of fibrinolysis; GO:0030193 regulation of blood coagulation; GO:0044267 cellular protein metabolic process; GO:0022408 negative regulation of cell-cell adhesion; GO:0002576 platelet degranulation; GO:0048519 negative regulation of biological process; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:0007599 hemostasis; GO:0051239 regulation of multicellular organismal process; GO:0071704 organic substance metabolic process; GO:1900047 negative regulation of hemostasis; GO:1902578 single-organism localization; GO:0043062 extracellular structure organization; GO:0006508 proteolysis; GO:0051919 positive regulation of fibrinolysis; GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin; GO:0009987 cellular process; GO:0048771 tissue remodeling; GO:0050878 regulation of body fluid levels; GO:0006950 response to stress; GO:0051917 regulation of fibrinolysis; GO:0016192 vesicle-mediated transport; GO:0032101 regulation of response to external stimulus; GO:0050820 positive regulation of coagulation; GO:0048585 negative regulation of response to stimulus; GO:0044238 primary metabolic process; GO:0061045 negative regulation of wound healing; GO:0048518 positive regulation of biological process; GO:0022407 regulation of cell-cell adhesion; GO:0030155 regulation of cell adhesion; GO:0050818 regulation of coagulation; GO:0030195 negative regulation of blood coagulation; GO:0045055 regulated exocytosis; GO:0061041 regulation of wound healing; GO:0042060 wound healing; GO:0022411 cellular component disassembly; GO:0010810 regulation of cell-substrate adhesion; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:1903034 regulation of response to wounding; GO:0050819 negative regulation of coagulation; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:0006887 exocytosis; ","GO:0034774 secretory granule lumen; GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0009897 external side of plasma membrane; GO:0031410 cytoplasmic vesicle; GO:0019898 extrinsic component of membrane; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0098552 side of membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0031232 extrinsic component of external side of plasma membrane; GO:0044446 intracellular organelle part; GO:0019897 extrinsic component of plasma membrane; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0072562 blood microparticle; GO:0060205 cytoplasmic vesicle lumen; GO:0044459 plasma membrane part; GO:0031093 platelet alpha granule lumen; GO:0009986 cell surface; GO:0031091 platelet alpha granule; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0004252 serine-type endopeptidase activity; GO:0004175 endopeptidase activity; GO:0008233 peptidase activity; GO:0034185 apolipoprotein binding; GO:0017171 serine hydrolase activity; GO:0005102 receptor binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0008236 serine-type peptidase activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0019904 protein domain specific binding; GO:0016787 hydrolase activity; GO:0005515 protein binding; ","K01315","PLG; plasminogen [EC:3.4.21.7]","hsa04610 Complement and coagulation cascades - Homo sapiens (human); hsa05150 Staphylococcus aureus infection - Homo sapiens (human); hsa05164 Influenza A - Homo sapiens (human); hsa04080 Neuroactive ligand-receptor interaction - Homo sapiens (human); ","IPR009003; IPR003609; IPR000001; IPR001254; IPR013806; ","\"Peptidase S1, PA clan; PAN/Apple domain; Kringle; Serine proteases, trypsin domain; Kringle-like fold; \"\r"]
["P00748","Coagulation factor XII OS=Homo sapiens OX=9606 GN=F12","F12",67.791,47.795,18,8,10,8,1.04,1.057,1.013,0.966,0.983,1.002,0.949,0.0323,"extracellular\r","GO:0002675 positive regulation of acute inflammatory response; GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0016485 protein processing; GO:0031347 regulation of defense response; GO:0042730 fibrinolysis; GO:0009611 response to wounding; GO:0008152 metabolic process; GO:0035966 response to topologically incorrect protein; GO:0051240 positive regulation of multicellular organismal process; GO:0009893 positive regulation of metabolic process; GO:0032102 negative regulation of response to external stimulus; GO:0032103 positive regulation of response to external stimulus; GO:1900046 regulation of hemostasis; GO:0090303 positive regulation of wound healing; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0030194 positive regulation of blood coagulation; GO:0031638 zymogen activation; GO:0010468 regulation of gene expression; GO:0007597 blood coagulation, intrinsic pathway; GO:0050729 positive regulation of inflammatory response; GO:0080090 regulation of primary metabolic process; GO:0048522 positive regulation of cellular process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:1903035 negative regulation of response to wounding; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:1900048 positive regulation of hemostasis; GO:0002526 acute inflammatory response; GO:0048583 regulation of response to stimulus; GO:0006954 inflammatory response; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0050817 coagulation; GO:1903317 regulation of protein maturation; GO:0006952 defense response; GO:0010755 regulation of plasminogen activation; GO:1903036 positive regulation of response to wounding; GO:0002353 plasma kallikrein-kinin cascade; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0002254 kinin cascade; GO:1903319 positive regulation of protein maturation; GO:0060255 regulation of macromolecule metabolic process; GO:0030193 regulation of blood coagulation; GO:0002673 regulation of acute inflammatory response; GO:0048519 negative regulation of biological process; GO:0080134 regulation of response to stress; GO:0050896 response to stimulus; GO:0045087 innate immune response; GO:0051239 regulation of multicellular organismal process; GO:0007599 hemostasis; GO:0071704 organic substance metabolic process; GO:1900047 negative regulation of hemostasis; GO:0016540 protein autoprocessing; GO:0031349 positive regulation of defense response; GO:0045862 positive regulation of proteolysis; GO:0010628 positive regulation of gene expression; GO:0006508 proteolysis; GO:0051919 positive regulation of fibrinolysis; GO:0002542 Factor XII activation; GO:0050878 regulation of body fluid levels; GO:0006950 response to stress; GO:0051788 response to misfolded protein; GO:0051917 regulation of fibrinolysis; GO:0002376 immune system process; GO:0032101 regulation of response to external stimulus; GO:0072376 protein activation cascade; GO:0050820 positive regulation of coagulation; GO:0048585 negative regulation of response to stimulus; GO:0030162 regulation of proteolysis; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0061045 negative regulation of wound healing; GO:0048518 positive regulation of biological process; GO:0072378 blood coagulation, fibrin clot formation; GO:0050818 regulation of coagulation; GO:0030195 negative regulation of blood coagulation; GO:0010954 positive regulation of protein processing; GO:0051247 positive regulation of protein metabolic process; GO:0061041 regulation of wound healing; GO:0042060 wound healing; GO:0051246 regulation of protein metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0070613 regulation of protein processing; GO:0050727 regulation of inflammatory response; GO:0010467 gene expression; GO:0006955 immune response; GO:0051604 protein maturation; GO:0048584 positive regulation of response to stimulus; GO:1903034 regulation of response to wounding; GO:0010756 positive regulation of plasminogen activation; GO:0050819 negative regulation of coagulation; GO:0065007 biological regulation; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0071944 cell periphery; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0005576 extracellular region; GO:0043230 extracellular organelle; GO:0005886 plasma membrane; ","GO:0008233 peptidase activity; GO:0043167 ion binding; GO:0008236 serine-type peptidase activity; GO:0051787 misfolded protein binding; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0004175 endopeptidase activity; GO:0004252 serine-type endopeptidase activity; GO:0003824 catalytic activity; GO:0017171 serine hydrolase activity; GO:0005488 binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005509 calcium ion binding; ","K01328","F12; coagulation factor XII (Hageman factor) [EC:3.4.21.38]","hsa04610 Complement and coagulation cascades - Homo sapiens (human); ","IPR000083; IPR000001; IPR001881; IPR000742; IPR013806; IPR000562; IPR009003; IPR001254; ","\"Fibronectin, type I; Kringle; EGF-like calcium-binding domain; EGF-like domain; Kringle-like fold; Fibronectin, type II, collagen-binding; Peptidase S1, PA clan; Serine proteases, trypsin domain; \"\r"]
["P00751","Complement factor B OS=Homo sapiens OX=9606 GN=CFB","CFB",85.532,157.66,35.5,26,51,26,1.029,1.008,0.994,0.998,0.97,0.99,0.976,0.138,"extracellular\r","GO:0030449 regulation of complement activation; GO:2000257 regulation of protein activation cascade; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0002920 regulation of humoral immune response; GO:0002673 regulation of acute inflammatory response; GO:0006959 humoral immune response; GO:0080134 regulation of response to stress; GO:0050896 response to stimulus; GO:0031347 regulation of defense response; GO:0045087 innate immune response; GO:0071704 organic substance metabolic process; GO:0006956 complement activation; GO:0008152 metabolic process; GO:0006508 proteolysis; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0050778 positive regulation of immune response; GO:0002697 regulation of immune effector process; GO:0010468 regulation of gene expression; GO:0002253 activation of immune response; GO:0006950 response to stress; GO:0080090 regulation of primary metabolic process; GO:0032101 regulation of response to external stimulus; GO:0002376 immune system process; GO:0072376 protein activation cascade; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0050776 regulation of immune response; GO:0050789 regulation of biological process; GO:0006957 complement activation, alternative pathway; GO:0051246 regulation of protein metabolic process; GO:0002684 positive regulation of immune system process; GO:0048583 regulation of response to stimulus; GO:0070613 regulation of protein processing; GO:0050727 regulation of inflammatory response; GO:0019222 regulation of metabolic process; GO:0002682 regulation of immune system process; GO:1903317 regulation of protein maturation; GO:0006952 defense response; GO:0048584 positive regulation of response to stimulus; GO:0006955 immune response; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0072562 blood microparticle; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0004252 serine-type endopeptidase activity; GO:0004175 endopeptidase activity; GO:0008233 peptidase activity; GO:0017171 serine hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0008236 serine-type peptidase activity; GO:0001848 complement binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0005515 protein binding; GO:0016787 hydrolase activity; ","K01335","CFB; component factor B [EC:3.4.21.47]","hsa04610 Complement and coagulation cascades - Homo sapiens (human); hsa05150 Staphylococcus aureus infection - Homo sapiens (human); ","IPR009003; IPR000436; IPR001254; IPR002035; ","\"Peptidase S1, PA clan; Sushi/SCR/CCP domain; Serine proteases, trypsin domain; von Willebrand factor, type A; \"\r"]
["P00813","Adenosine deaminase OS=Homo sapiens OX=9606 GN=ADA","ADA",40.764,32.815,14.3,4,6,4,1.3,1.326,1.372,0.664,0.674,0.675,0.504,1.02E-6,"cytoplasm\r",{"$cut":{"chars":19257,"head":"GO:0002694 regulation of leukocyte activation; GO:0010941 regulation of cell death; GO:0048732 gland development; GO:0022414 reproductive process; GO:0043009 chordate embryonic development; GO:0030323 respiratory tube development; GO:0031347 regulation of defense response; GO:0044237 cellular metabolic process; GO:0030888 regulation of B cell proliferation; GO:0042110 T cell activation; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0032946 positive regulation of mononuclear cell proliferation; GO:0045187 regulation of circadian sleep/wake cycle, sleep; GO:0014072 response to isoquinoline alkaloid; GO:0044057 regulation of system process; GO:0002314 germinal center B cell differentiation; GO:0045621 positive regulation of lymphocyte differentiation; GO:0009790 embryo development; GO:0051051 negative regulation of transport; GO:0046101 hypoxanthine biosynthetic process; GO:0046122 purine deoxyribonucleoside metabolic process; GO:0060359 response to ammonium ion; GO:0050864 regulation of B cell activation; GO:0009215 purine deoxyribonucleoside triphosphate metabolic process; GO:0002905 regulation of mature B cell apoptotic process; GO:0070229 negative regulation of lymphocyte apoptotic process; GO:0044763 single-organism cellular process; GO:0002335 mature B cell differentiation; GO:0002520 immune system development; GO:0009168 purine ribonucleoside monophosphate biosynthetic process; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0019439 aromatic compound catabolic process; GO:1901575 organic substance catabolic process; GO:0010243 response to organonitrogen compound; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0009112 nucleobase metabolic process; GO:0060548 negative regulation of cell death; GO:0000003 reproduction; GO:0042754 negative regulation of circadian rhythm; GO:0044707 single-multicellular organism process; GO:0001829 trophectodermal cell differentiation; GO:0051608 histamine transport; GO:0045580 regulation of T cell differentiation; GO:0050728 negative regulation of inflammatory response; GO:1901700 response to oxygen-containing compound; GO:0048519 negative regulation of biological process; GO:0001825 blastocyst formation; GO:1903706 regulation of hemopoiesis; GO:0030098 lymphocyte differentiation; GO:0042493 response to drug; GO:0009653 anatomical structure morphogenesis; GO:0044270 cellular nitrogen compound catabolic process; GO:0050867 positive regulation of cell activation; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:2000145 regulation of cell motility; GO:0060541 respiratory system development; GO:0070482 response to oxygen levels; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:0044248 cellular catabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0050848 regulation of calcium-mediated signaling; GO:0061458 reproductive system development; GO:0060167 regulation of adenosine receptor signaling pathway; GO:0050778 positive regulation of immune response; GO:0009151 purine deoxyribonucleotide metabolic process; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0045785 positive regulation of cell adhesion; GO:0006950 response to stress; GO:0044711 single-organism biosynthetic process; GO:0051270 regulation of cellular component movement; GO:0055123 digestive system development; GO:1901293 nucleoside phosphate biosynthetic process; GO:0032101 regulation of response to external stimulus; GO:0009141 nucleoside triphosphate metabolic process; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0006144 purine nucleobase metabolic process; GO:0007584 response to nutrient; GO:1903039 positive regulation of leukocyte cell-cell adhesion; GO:1901576 organic substance biosynthetic process; GO:0002263 cell "}},"GO:0030425 dendrite; GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0009897 external side of plasma membrane; GO:0031410 cytoplasmic vesicle; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0099568 cytoplasmic region; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032838 cell projection cytoplasm; GO:0043025 neuronal cell body; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0032839 dendrite cytoplasm; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0005764 lysosome; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0098552 side of membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0044446 intracellular organelle part; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0060205 cytoplasmic vesicle lumen; GO:0044459 plasma membrane part; GO:0005773 vacuole; GO:0044297 cell body; GO:0009986 cell surface; GO:0044444 cytoplasmic part; ","GO:0004000 adenosine deaminase activity; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0008270 zinc ion binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0097367 carbohydrate derivative binding; GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0019239 deaminase activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0001883 purine nucleoside binding; GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; GO:0036094 small molecule binding; ","K01488","add; adenosine deaminase [EC:3.5.4.4]","hsa00230 Purine metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa05340 Primary immunodeficiency - Homo sapiens (human); ","IPR001365; IPR032466; ","Adenosine/AMP deaminase domain; Metal-dependent hydrolase; \r"]
["P00846","ATP synthase subunit a OS=Homo sapiens OX=9606 GN=MT-ATP6","MT-ATP6",24.817,9.8542,8.4,2,3,2,1.057,1.095,1.138,0.882,0.896,0.95,0.829,3.8E-3,"plasma membrane\r","GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0006839 mitochondrial transport; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0046129 purine ribonucleoside biosynthetic process; GO:0009163 nucleoside biosynthetic process; GO:0009156 ribonucleoside monophosphate biosynthetic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0046390 ribose phosphate biosynthetic process; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:1901137 carbohydrate derivative biosynthetic process; GO:0006753 nucleoside phosphate metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0009145 purine nucleoside triphosphate biosynthetic process; GO:0044765 single-organism transport; GO:0032502 developmental process; GO:0018130 heterocycle biosynthetic process; GO:0098655 cation transmembrane transport; GO:0009206 purine ribonucleoside triphosphate biosynthetic process; GO:0044281 small molecule metabolic process; GO:0006754 ATP biosynthetic process; GO:0044763 single-organism cellular process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0015985 energy coupled proton transport, down electrochemical gradient; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0009168 purine ribonucleoside monophosphate biosynthetic process; GO:1902582 single-organism intracellular transport; GO:0042451 purine nucleoside biosynthetic process; GO:0036296 response to increased oxygen levels; GO:0090407 organophosphate biosynthetic process; GO:0006810 transport; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0072522 purine-containing compound biosynthetic process; GO:0007568 aging; GO:0015986 ATP synthesis coupled proton transport; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0006164 purine nucleotide biosynthetic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0098662 inorganic cation transmembrane transport; GO:0009201 ribonucleoside triphosphate biosynthetic process; GO:0046907 intracellular transport; GO:0034220 ion transmembrane transport; GO:0009165 nucleotide biosynthetic process; GO:0042776 mitochondrial ATP synthesis coupled proton transport; GO:0006725 cellular aromatic compound metabolic process; GO:0009628 response to abiotic stimulus; GO:0009259 ribonucleotide metabolic process; GO:0009142 nucleoside triphosphate biosynthetic process; GO:0050896 response to stimulus; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0006812 cation transport; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:1990542 mitochondrial transmembrane transport; GO:0070482 response to oxygen levels; GO:1901135 carbohydrate derivative metabolic process; GO:1902600 hydrogen ion transmembrane transport; GO:0034641 cellular nitrogen compound metabolic process; GO:1902580 single-organism cellular localization; GO:0055093 response to hyperoxia; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0009119 ribonucleoside metabolic process; GO:0046034 ATP metabolic process; GO:0009124 nucleoside monophosphate biosynthetic process; GO:0006950 response to stress; GO:0044711 single-organism biosynthetic process; GO:0098660 inorganic ion transmembrane transport; GO:0009127 purine nucleoside monophosphate biosynthetic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0042455 ribonucleoside biosynthetic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0006163 purine nucleotide metabolic process; GO:0006818 hydrogen transport; GO:0015992 proton transport; GO:0051641 cellular localization; GO:0046128 purine ribonucleoside metabolic process; GO:0055085 transmembrane transport; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0009152 purine ribonucleotide biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0044767 single-organism developmental process; GO:1901659 glycosyl compound biosynthetic process; GO:0006811 ion transport; GO:0009260 ribonucleotide biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0051179 localization; GO:0015672 monovalent inorganic cation transport; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0019866 organelle inner membrane; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain; GO:0005743 mitochondrial inner membrane; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0045259 proton-transporting ATP synthase complex; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005753 mitochondrial proton-transporting ATP synthase complex; GO:0016469 proton-transporting two-sector ATPase complex; GO:0031975 envelope; GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o); GO:0043234 protein complex; GO:0031966 mitochondrial membrane; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0015075 ion transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0015077 monovalent inorganic cation transmembrane transporter activity; GO:0022890 inorganic cation transmembrane transporter activity; GO:0015078 hydrogen ion transmembrane transporter activity; GO:0008324 cation transmembrane transporter activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; ","K02126","ATPeF0A; F-type H+-transporting ATPase subunit a","hsa05010 Alzheimer's disease - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); "]
["P00915","Carbonic anhydrase 1 OS=Homo sapiens OX=9606 GN=CA1","CA1",28.87,171.16,59.4,13,60,13,0.842,0.838,0.827,1.132,1.156,1.199,1.391,4.41e-05,"cytoplasm\r","GO:0006810 transport; GO:0006820 anion transport; GO:0015711 organic anion transport; GO:0008152 metabolic process; GO:0006730 one-carbon metabolic process; GO:0006811 ion transport; GO:0044710 single-organism metabolic process; GO:0044281 small molecule metabolic process; GO:0015701 bicarbonate transport; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0071702 organic substance transport; GO:0051179 localization; GO:0009987 cellular process; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0052689 carboxylic ester hydrolase activity; GO:0043167 ion binding; GO:0016829 lyase activity; GO:0016836 hydro-lyase activity; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0008270 zinc ion binding; GO:0004089 carbonate dehydratase activity; GO:0016835 carbon-oxygen lyase activity; GO:0004064 arylesterase activity; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0046872 metal ion binding; GO:0043169 cation binding; ","K01672","CA; carbonic anhydrase [EC:4.2.1.1]","hsa00910 Nitrogen metabolism - Homo sapiens (human); ","IPR001148; ","Alpha carbonic anhydrase; \r"]
["P00918","Carbonic anhydrase 2 OS=Homo sapiens OX=9606 GN=CA2","CA2",29.246,145.25,58.1,13,24,13,1.013,0.895,0.954,0.996,1.076,1.016,1.079,0.146,"cytoplasm\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:1904385 cellular response to angiotensin; GO:0030641 regulation of cellular pH; GO:0030004 cellular monovalent inorganic cation homeostasis; GO:0032847 regulation of cellular pH reduction; GO:0044237 cellular metabolic process; GO:0032228 regulation of synaptic transmission, GABAergic; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0048545 response to steroid hormone; GO:0009719 response to endogenous stimulus; GO:1901652 response to peptide; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0051716 cellular response to stimulus; GO:0014070 response to organic cyclic compound; GO:0071498 cellular response to fluid shear stress; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0043269 regulation of ion transport; GO:0032501 multicellular organismal process; GO:0034762 regulation of transmembrane transport; GO:0006810 transport; GO:0010243 response to organonitrogen compound; GO:0048513 animal organ development; GO:0044710 single-organism metabolic process; GO:0045780 positive regulation of bone resorption; GO:1901698 response to nitrogen compound; GO:0009887 animal organ morphogenesis; GO:0002682 regulation of immune system process; GO:0045670 regulation of osteoclast differentiation; GO:0051094 positive regulation of developmental process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:2000880 positive regulation of dipeptide transport; GO:0044707 single-multicellular organism process; GO:0002009 morphogenesis of an epithelium; GO:0034764 positive regulation of transmembrane transport; GO:0006885 regulation of pH; GO:0045672 positive regulation of osteoclast differentiation; GO:0009628 response to abiotic stimulus; GO:1901700 response to oxygen-containing compound; GO:0090089 regulation of dipeptide transport; GO:0032844 regulation of homeostatic process; GO:0046850 regulation of bone remodeling; GO:0045597 positive regulation of cell differentiation; GO:0051239 regulation of multicellular organismal process; GO:1903706 regulation of hemopoiesis; GO:0009653 anatomical structure morphogenesis; GO:1902578 single-organism localization; GO:0010043 response to zinc ion; GO:0007275 multicellular organism development; GO:2001150 positive regulation of dipeptide transmembrane transport; GO:0048878 chemical homeostasis; GO:0090087 regulation of peptide transport; GO:0001822 kidney development; GO:0006950 response to stress; GO:0048731 system development; GO:0050804 modulation of synaptic transmission; GO:0071702 organic substance transport; GO:0002763 positive regulation of myeloid leukocyte differentiation; GO:0010033 response to organic substance; GO:0007186 G-protein coupled receptor signaling pathway; GO:0019755 one-carbon compound transport; GO:0006873 cellular ion homeostasis; GO:0051453 regulation of intracellular pH; GO:0006811 ion transport; GO:0002761 regulation of myeloid leukocyte differentiation; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0043627 response to estrogen; GO:0045637 regulation of myeloid cell differentiation; GO:0044070 regulation of anion transport; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0034103 regulation of tissue remodeling; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:0048729 tissue morphogenesis; GO:1902107 positive regulation of leukocyte differentiation; GO:0050806 positive regulation of synaptic transmission; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:1901653 cellular response to peptide; GO:0032846 positive regulation of homeostatic process; GO:0042475 odontogenesis of dentin-containing tooth; GO:0010035 response to inorganic substance; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0009888 tissue development; GO:0050801 ion homeostasis; GO:0098771 inorganic ion homeostasis; GO:0038166 angiotensin-activated signaling pathway; GO:0048522 positive regulation of cellular process; GO:0019725 cellular homeostasis; GO:2001225 regulation of chloride transport; GO:0023052 signaling; GO:0010038 response to metal ion; GO:0042476 odontogenesis; GO:0051050 positive regulation of transport; GO:0071417 cellular response to organonitrogen compound; GO:0001655 urogenital system development; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0015670 carbon dioxide transport; GO:0043434 response to peptide hormone; GO:1901699 cellular response to nitrogen compound; GO:0032870 cellular response to hormone stimulus; GO:0045639 positive regulation of myeloid cell differentiation; GO:1902105 regulation of leukocyte differentiation; GO:2000878 positive regulation of oligopeptide transport; GO:2001148 regulation of dipeptide transmembrane transport; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0015669 gas transport; GO:2000021 regulation of ion homeostasis; GO:0030003 cellular cation homeostasis; GO:0071310 cellular response to organic substance; GO:0072001 renal system development; GO:0045124 regulation of bone resorption; GO:0050896 response to stimulus; GO:0055082 cellular chemical homeostasis; GO:0042592 homeostatic process; GO:0033993 response to lipid; GO:0009268 response to pH; GO:0006730 one-carbon metabolic process; GO:0032849 positive regulation of cellular pH reduction; GO:0055080 cation homeostasis; GO:0023056 positive regulation of signaling; GO:0071375 cellular response to peptide hormone stimulus; GO:0015701 bicarbonate transport; GO:0032230 positive regulation of synaptic transmission, GABAergic; GO:0010647 positive regulation of cell communication; GO:0034405 response to fluid shear stress; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0055067 monovalent inorganic cation homeostasis; GO:1903708 positive regulation of hemopoiesis; GO:0034105 positive regulation of tissue remodeling; GO:0051049 regulation of transport; GO:0046852 positive regulation of bone remodeling; GO:1990776 response to angiotensin; GO:0090088 regulation of oligopeptide transport; GO:0048518 positive regulation of biological process; GO:0006820 anion transport; GO:0015711 organic anion transport; GO:1901701 cellular response to oxygen-containing compound; GO:0071495 cellular response to endogenous stimulus; GO:0044767 single-organism developmental process; GO:0002684 positive regulation of immune system process; GO:0009725 response to hormone; GO:0065007 biological regulation; ","GO:0016323 basolateral plasma membrane; GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0098858 actin-based cell projection; GO:0005623 cell; GO:0070062 extracellular exosome; GO:0098590 plasma membrane region; GO:0043209 myelin sheath; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0045177 apical part of cell; GO:0042995 cell projection; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0030424 axon; GO:0044459 plasma membrane part; GO:0005902 microvillus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0052689 carboxylic ester hydrolase activity; GO:0043167 ion binding; GO:0016829 lyase activity; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0016836 hydro-lyase activity; GO:0008270 zinc ion binding; GO:0004089 carbonate dehydratase activity; GO:0016835 carbon-oxygen lyase activity; GO:0004064 arylesterase activity; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0046872 metal ion binding; GO:0043169 cation binding; ","K18245","CA2; carbonic anhydrase 2 [EC:4.2.1.1]","hsa04966 Collecting duct acid secretion - Homo sapiens (human); hsa04976 Bile secretion - Homo sapiens (human); hsa04972 Pancreatic secretion - Homo sapiens (human); hsa00910 Nitrogen metabolism - Homo sapiens (human); hsa04964 Proximal tubule bicarbonate reclamation - Homo sapiens (human); hsa04971 Gastric acid secretion - Homo sapiens (human); ","IPR001148; ","Alpha carbonic anhydrase; \r"]
["P00966","Argininosuccinate synthase OS=Homo sapiens OX=9606 GN=ASS1","ASS1",46.53,51.596,22.8,10,19,10,1.051,1.025,1.024,0.966,0.912,0.971,0.919,0.0178,"cytoplasm\r","GO:0045428 regulation of nitric oxide biosynthetic process; GO:0016053 organic acid biosynthetic process; GO:0009891 positive regulation of biosynthetic process; GO:0071499 cellular response to laminar fluid shear stress; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0009084 glutamine family amino acid biosynthetic process; GO:0071941 nitrogen cycle metabolic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:1901607 alpha-amino acid biosynthetic process; GO:0000050 urea cycle; GO:0045429 positive regulation of nitric oxide biosynthetic process; GO:0051716 cellular response to stimulus; GO:0072350 tricarboxylic acid metabolic process; GO:0071498 cellular response to fluid shear stress; GO:0031326 regulation of cellular biosynthetic process; GO:1903038 negative regulation of leukocyte cell-cell adhesion; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006525 arginine metabolic process; GO:0048522 positive regulation of cellular process; GO:0043603 cellular amide metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0034616 response to laminar fluid shear stress; GO:0046394 carboxylic acid biosynthetic process; GO:0050789 regulation of biological process; GO:0044710 single-organism metabolic process; GO:1904407 positive regulation of nitric oxide metabolic process; GO:0019222 regulation of metabolic process; GO:0006082 organic acid metabolic process; GO:2000377 regulation of reactive oxygen species metabolic process; GO:0000052 citrulline metabolic process; GO:0043436 oxoacid metabolic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0043648 dicarboxylic acid metabolic process; GO:0007162 negative regulation of cell adhesion; GO:1903428 positive regulation of reactive oxygen species biosynthetic process; GO:0006526 arginine biosynthetic process; GO:0000053 argininosuccinate metabolic process; GO:0009066 aspartate family amino acid metabolic process; GO:0022408 negative regulation of cell-cell adhesion; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0006575 cellular modified amino acid metabolic process; GO:0009889 regulation of biosynthetic process; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034405 response to fluid shear stress; GO:0009987 cellular process; GO:0009064 glutamine family amino acid metabolic process; GO:0008652 cellular amino acid biosynthetic process; GO:0019627 urea metabolic process; GO:0044711 single-organism biosynthetic process; GO:0006950 response to stress; GO:1903426 regulation of reactive oxygen species biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:1901605 alpha-amino acid metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0022407 regulation of cell-cell adhesion; GO:0030155 regulation of cell adhesion; GO:2000379 positive regulation of reactive oxygen species metabolic process; GO:0006531 aspartate metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0031325 positive regulation of cellular metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0044283 small molecule biosynthetic process; GO:0043604 amide biosynthetic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043209 myelin sheath; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016597 amino acid binding; GO:0004055 argininosuccinate synthase activity; GO:1901265 nucleoside phosphate binding; GO:0016874 ligase activity; GO:0005515 protein binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0042802 identical protein binding; GO:0031406 carboxylic acid binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003723 RNA binding; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0043177 organic acid binding; GO:0000166 nucleotide binding; GO:0016879 ligase activity, forming carbon-nitrogen bonds; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003676 nucleic acid binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; ","K01940","argG; argininosuccinate synthase [EC:6.3.4.5]","hsa00220 Arginine biosynthesis - Homo sapiens (human); hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00250 Alanine, aspartate and glutamate metabolism - Homo sapiens (human); hsa01230 Biosynthesis of amino acids - Homo sapiens (human); ","IPR014729; IPR024074; ","\"Rossmann-like alpha/beta/alpha sandwich fold; Argininosuccinate synthetase, catalytic/multimerisation domain body; \"\r"]
["P00973","2'-5'-oligoadenylate synthase 1 OS=Homo sapiens OX=9606 GN=OAS1","OAS1",46.028,4.2881,2.5,1,1,1,0.779,0.919,0.676,1.211,1.186,1.215,1.521,0.0408,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0007166 cell surface receptor signaling pathway; GO:0009117 nucleotide metabolic process; GO:0042593 glucose homeostasis; GO:0098542 defense response to other organism; GO:0071346 cellular response to interferon-gamma; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0071345 cellular response to cytokine stimulus; GO:0006796 phosphate-containing compound metabolic process; GO:0009607 response to biotic stimulus; GO:0006006 glucose metabolic process; GO:0060333 interferon-gamma-mediated signaling pathway; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0006753 nucleoside phosphate metabolic process; GO:0065003 macromolecular complex assembly; GO:0044419 interspecies interaction between organisms; GO:0070887 cellular response to chemical stimulus; GO:0048525 negative regulation of viral process; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0071822 protein complex subunit organization; GO:0034097 response to cytokine; GO:0080090 regulation of primary metabolic process; GO:0060700 regulation of ribonuclease activity; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0072521 purine-containing compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0034340 response to type I interferon; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0045069 regulation of viral genome replication; GO:0005975 carbohydrate metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0023052 signaling; GO:0051704 multi-organism process; GO:0090407 organophosphate biosynthetic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0051607 defense response to virus; GO:0051336 regulation of hydrolase activity; GO:0072522 purine-containing compound biosynthetic process; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0006952 defense response; GO:0006164 purine nucleotide biosynthetic process; GO:0070271 protein complex biogenesis; GO:1901362 organic cyclic compound biosynthetic process; GO:0009615 response to virus; GO:0050794 regulation of cellular process; GO:0060337 type I interferon signaling pathway; GO:0016043 cellular component organization; GO:0009165 nucleotide biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0043207 response to external biotic stimulus; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0045087 innate immune response; GO:0035457 cellular response to interferon-alpha; GO:0071704 organic substance metabolic process; GO:0051259 protein oligomerization; GO:1903901 negative regulation of viral life cycle; GO:0042592 homeostatic process; GO:0032069 regulation of nuclease activity; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0016032 viral process; GO:0005996 monosaccharide metabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0033500 carbohydrate homeostasis; GO:0034641 cellular nitrogen compound metabolic process; GO:0071357 cellular response to type I interferon; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0019221 cytokine-mediated signaling pathway; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0048878 chemical homeostasis; GO:0044711 single-organism biosynthetic process; GO:0006950 response to stress; GO:0043900 regulation of multi-organism process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0050792 regulation of viral process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0002376 immune system process; GO:0034341 response to interferon-gamma; GO:0010033 response to organic substance; GO:0045071 negative regulation of viral genome replication; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0006163 purine nucleotide metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0043901 negative regulation of multi-organism process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0019637 organophosphate metabolic process; GO:0035455 response to interferon-alpha; GO:0006955 immune response; GO:1903900 regulation of viral life cycle; GO:1901564 organonitrogen compound metabolic process; GO:0019318 hexose metabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0005783 endoplasmic reticulum; GO:0005737 cytoplasm; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0005515 protein binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003723 RNA binding; GO:0005524 ATP binding; GO:0003725 double-stranded RNA binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0008270 zinc ion binding; GO:0001730 2'-5'-oligoadenylate synthetase activity; GO:0070566 adenylyltransferase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0046914 transition metal ion binding; GO:0016779 nucleotidyltransferase activity; GO:0003676 nucleic acid binding; GO:0046872 metal ion binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0036094 small molecule binding; ","K14216","OAS; 2'-5'-oligoadenylate synthetase [EC:2.7.7.84]","hsa05162 Measles - Homo sapiens (human); hsa05168 Herpes simplex infection - Homo sapiens (human); hsa05160 Hepatitis C - Homo sapiens (human); hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human); hsa05164 Influenza A - Homo sapiens (human); ","IPR002934; IPR018952; IPR006116; ","\"Polymerase, nucleotidyl transferase domain; 2'-5'-oligoadenylate synthetase 1, domain 2/C-terminal; 2-5-oligoadenylate synthetase, N-terminal; \"\r"]
["P01008","Antithrombin-III OS=Homo sapiens OX=9606 GN=SERPINC1","SERPINC1",52.602,157.93,43.1,25,51,25,1.038,1.005,1.008,0.987,0.996,0.974,0.969,0.0624,"extracellular\r","GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0048732 gland development; GO:0044699 single-organism process; GO:0051234 establishment of localization; GO:0009611 response to wounding; GO:0009605 response to external stimulus; GO:0010466 negative regulation of peptidase activity; GO:1900046 regulation of hemostasis; GO:0002437 inflammatory response to antigenic stimulus; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0052548 regulation of endopeptidase activity; GO:2000266 regulation of blood coagulation, intrinsic pathway; GO:0032502 developmental process; GO:0007595 lactation; GO:0080090 regulation of primary metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0043086 negative regulation of catalytic activity; GO:0010605 negative regulation of macromolecule metabolic process; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:0048513 animal organ development; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:0002526 acute inflammatory response; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0006954 inflammatory response; GO:0048583 regulation of response to stimulus; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0006952 defense response; GO:0050817 coagulation; GO:0052547 regulation of peptidase activity; GO:0048856 anatomical structure development; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:2000257 regulation of protein activation cascade; GO:0010951 negative regulation of endopeptidase activity; GO:0060255 regulation of macromolecule metabolic process; GO:0030193 regulation of blood coagulation; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0007599 hemostasis; GO:0051239 regulation of multicellular organismal process; GO:0051346 negative regulation of hydrolase activity; GO:0030879 mammary gland development; GO:0009991 response to extracellular stimulus; GO:1902578 single-organism localization; GO:0007275 multicellular organism development; GO:0002438 acute inflammatory response to antigenic stimulus; GO:0007589 body fluid secretion; GO:0045861 negative regulation of proteolysis; GO:0050878 regulation of body fluid levels; GO:0006950 response to stress; GO:0048731 system development; GO:0002376 immune system process; GO:0032101 regulation of response to external stimulus; GO:0030162 regulation of proteolysis; GO:0007584 response to nutrient; GO:0009892 negative regulation of metabolic process; GO:0050818 regulation of coagulation; GO:0061041 regulation of wound healing; GO:0042060 wound healing; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0051248 negative regulation of protein metabolic process; GO:0031667 response to nutrient levels; GO:0006955 immune response; GO:0051179 localization; GO:1903034 regulation of response to wounding; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0072562 blood microparticle; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0061134 peptidase regulator activity; GO:0043167 ion binding; GO:0005515 protein binding; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0008201 heparin binding; GO:0004866 endopeptidase inhibitor activity; GO:1901681 sulfur compound binding; GO:0002020 protease binding; GO:0097367 carbohydrate derivative binding; GO:0004867 serine-type endopeptidase inhibitor activity; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0030414 peptidase inhibitor activity; GO:0043168 anion binding; GO:0061135 endopeptidase regulator activity; GO:0005539 glycosaminoglycan binding; GO:0019899 enzyme binding; ","K03911","SERPINC1; antithrombin III","hsa04610 Complement and coagulation cascades - Homo sapiens (human); ","IPR033829; IPR023796; ","Antithrombin serpin domain; Serpin domain; \r"]
["P01009","Alpha-1-antitrypsin OS=Homo sapiens OX=9606 GN=SERPINA1","SERPINA1",46.736,323.31,63.4,30,147,30,1.045,1.038,1.042,0.97,0.958,0.949,0.921,0.000239,"extracellular\r","GO:0044085 cellular component biogenesis; GO:0006901 vesicle coating; GO:0048207 vesicle targeting, rough ER to cis-Golgi; GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0048208 COPII vesicle coating; GO:0044699 single-organism process; GO:0051234 establishment of localization; GO:0009611 response to wounding; GO:0010466 negative regulation of peptidase activity; GO:0051649 establishment of localization in cell; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0048199 vesicle targeting, to, from or within Golgi; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0052548 regulation of endopeptidase activity; GO:0051650 establishment of vesicle localization; GO:0002443 leukocyte mediated immunity; GO:0071822 protein complex subunit organization; GO:0080090 regulation of primary metabolic process; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0006953 acute-phase response; GO:0051336 regulation of hydrolase activity; GO:0002526 acute inflammatory response; GO:0032940 secretion by cell; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0006954 inflammatory response; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0006952 defense response; GO:0043299 leukocyte degranulation; GO:0050817 coagulation; GO:0070271 protein complex biogenesis; GO:0052547 regulation of peptidase activity; GO:0050794 regulation of cellular process; GO:0051640 organelle localization; GO:0044707 single-multicellular organism process; GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0010951 negative regulation of endopeptidase activity; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0002576 platelet degranulation; GO:0048193 Golgi vesicle transport; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0006903 vesicle targeting; GO:0050896 response to stimulus; GO:0051346 negative regulation of hydrolase activity; GO:0007599 hemostasis; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0051648 vesicle localization; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0045861 negative regulation of proteolysis; GO:0050878 regulation of body fluid levels; GO:0006950 response to stress; GO:0090114 COPII-coated vesicle budding; GO:0016192 vesicle-mediated transport; GO:0016050 vesicle organization; GO:0002376 immune system process; GO:0030162 regulation of proteolysis; GO:0043312 neutrophil degranulation; GO:0051656 establishment of organelle localization; GO:0002263 cell activation involved in immune response; GO:0009892 negative regulation of metabolic process; GO:0051641 cellular localization; GO:0043933 macromolecular complex subunit organization; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0042060 wound healing; GO:0006996 organelle organization; GO:0051246 regulation of protein metabolic process; GO:0006900 membrane budding; GO:0061024 membrane organization; GO:0001775 cell activation; GO:0051248 negative regulation of protein metabolic process; GO:0006955 immune response; GO:0051179 localization; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0006887 exocytosis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005788 endoplasmic reticulum lumen; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0030134 ER to Golgi transport vesicle; GO:0012505 endomembrane system; GO:0030135 coated vesicle; GO:0005576 extracellular region; GO:0031012 extracellular matrix; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0044432 endoplasmic reticulum part; GO:0005793 endoplasmic reticulum-Golgi intermediate compartment; GO:0005578 proteinaceous extracellular matrix; GO:0031093 platelet alpha granule lumen; GO:0031091 platelet alpha granule; GO:0030133 transport vesicle; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0061134 peptidase regulator activity; GO:0005515 protein binding; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0004866 endopeptidase inhibitor activity; GO:0002020 protease binding; GO:0004867 serine-type endopeptidase inhibitor activity; GO:0097367 carbohydrate derivative binding; GO:0042802 identical protein binding; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0030414 peptidase inhibitor activity; GO:0061135 endopeptidase regulator activity; GO:0001948 glycoprotein binding; GO:0019899 enzyme binding; ","K03984","SERPINA1; alpha-1-antitrypsin","hsa04610 Complement and coagulation cascades - Homo sapiens (human); ","IPR023796; ","Serpin domain; \r"]
["P01011","Alpha-1-antichymotrypsin OS=Homo sapiens OX=9606 GN=SERPINA3","SERPINA3",47.65,183.52,32.2,13,37,13,1.006,0.982,0.969,0.998,1.05,1.01,1.034,0.15,"extracellular\r","GO:0065008 regulation of biological quality; GO:0007586 digestion; GO:0045321 leukocyte activation; GO:0044699 single-organism process; GO:0019216 regulation of lipid metabolic process; GO:0048871 multicellular organismal homeostasis; GO:0030277 maintenance of gastrointestinal epithelium; GO:0051234 establishment of localization; GO:0010466 negative regulation of peptidase activity; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0052548 regulation of endopeptidase activity; GO:0002443 leukocyte mediated immunity; GO:0080090 regulation of primary metabolic process; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0006953 acute-phase response; GO:0051336 regulation of hydrolase activity; GO:0002526 acute inflammatory response; GO:0032940 secretion by cell; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0006954 inflammatory response; GO:0001894 tissue homeostasis; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0006952 defense response; GO:0043299 leukocyte degranulation; GO:0052547 regulation of peptidase activity; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0010951 negative regulation of endopeptidase activity; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0002576 platelet degranulation; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0060249 anatomical structure homeostasis; GO:0051346 negative regulation of hydrolase activity; GO:0042592 homeostatic process; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0036230 granulocyte activation; GO:0010669 epithelial structure maintenance; GO:0009987 cellular process; GO:0045861 negative regulation of proteolysis; GO:0003008 system process; GO:0006950 response to stress; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0030162 regulation of proteolysis; GO:0043312 neutrophil degranulation; GO:0009892 negative regulation of metabolic process; GO:0002263 cell activation involved in immune response; GO:0002366 leukocyte activation involved in immune response; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:0051246 regulation of protein metabolic process; GO:0022600 digestive system process; GO:0051248 negative regulation of protein metabolic process; GO:0001775 cell activation; GO:0051179 localization; GO:0006955 immune response; GO:0065007 biological regulation; GO:0006887 exocytosis; ","GO:0034774 secretory granule lumen; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0042582 azurophil granule; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0072562 blood microparticle; GO:0060205 cytoplasmic vesicle lumen; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0031093 platelet alpha granule lumen; GO:0031091 platelet alpha granule; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003677 DNA binding; GO:0004867 serine-type endopeptidase inhibitor activity; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0030414 peptidase inhibitor activity; GO:0061134 peptidase regulator activity; GO:0003676 nucleic acid binding; GO:0061135 endopeptidase regulator activity; GO:0005515 protein binding; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0004866 endopeptidase inhibitor activity; ","K04525",null,null,"IPR023796; ","Serpin domain; \r"]
["P01019","Angiotensinogen OS=Homo sapiens OX=9606 GN=AGT","AGT",53.154,60.631,16.5,7,16,7,0.985,1.031,0.938,0.995,1.066,0.998,1.036,0.376,"extracellular\r",{"$cut":{"chars":29238,"head":"GO:0044700 single organism signaling; GO:0022414 reproductive process; GO:0014742 positive regulation of muscle hypertrophy; GO:0044237 cellular metabolic process; GO:0001558 regulation of cell growth; GO:0010536 positive regulation of activation of Janus kinase activity; GO:0035411 catenin import into nucleus; GO:0003298 physiological muscle hypertrophy; GO:0055065 metal ion homeostasis; GO:0044057 regulation of system process; GO:0006606 protein import into nucleus; GO:0055013 cardiac muscle cell development; GO:0046324 regulation of glucose import; GO:1900274 regulation of phospholipase C activity; GO:0052548 regulation of endopeptidase activity; GO:0080090 regulation of primary metabolic process; GO:0060537 muscle tissue development; GO:0090287 regulation of cellular response to growth factor stimulus; GO:0051353 positive regulation of oxidoreductase activity; GO:1901343 negative regulation of vasculature development; GO:0010666 positive regulation of cardiac muscle cell apoptotic process; GO:0035296 regulation of tube diameter; GO:0006810 transport; GO:0051092 positive regulation of NF-kappaB transcription factor activity; GO:0006939 smooth muscle contraction; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:1904752 regulation of vascular associated smooth muscle cell migration; GO:0032412 regulation of ion transmembrane transporter activity; GO:0048169 regulation of long-term neuronal synaptic plasticity; GO:0060419 heart growth; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0072359 circulatory system development; GO:0016310 phosphorylation; GO:0044707 single-multicellular organism process; GO:0051386 regulation of neurotrophin TRK receptor signaling pathway; GO:1904707 positive regulation of vascular smooth muscle cell proliferation; GO:2000650 negative regulation of sodium ion transmembrane transporter activity; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0009889 regulation of biosynthetic process; GO:0061061 muscle structure development; GO:0010959 regulation of metal ion transport; GO:0044744 protein targeting to nucleus; GO:1902680 positive regulation of RNA biosynthetic process; GO:0035150 regulation of tube size; GO:0032409 regulation of transporter activity; GO:0048878 chemical homeostasis; GO:0002018 renin-angiotensin regulation of aldosterone production; GO:0023014 signal transduction by protein phosphorylation; GO:0001822 kidney development; GO:1902826 regulation of L-arginine import into cell; GO:0042310 vasoconstriction; GO:0010872 regulation of cholesterol esterification; GO:0034104 negative regulation of tissue remodeling; GO:0050804 modulation of synaptic transmission; GO:0032101 regulation of response to external stimulus; GO:0008283 cell proliferation; GO:0044062 regulation of excretion; GO:0010033 response to organic substance; GO:0014911 positive regulation of smooth muscle cell migration; GO:0034766 negative regulation of ion transmembrane transport; GO:0048659 smooth muscle cell proliferation; GO:0001816 cytokine production; GO:0043412 macromolecule modification; GO:0003071 renal system process involved in regulation of systemic arterial blood pressure; GO:0003330 regulation of extracellular matrix constituent secretion; GO:0008284 positive regulation of cell proliferation; GO:0032930 positive regulation of superoxide anion generation; GO:0051093 negative regulation of developmental process; GO:0003012 muscle system process; GO:0072594 establishment of protein localization to organelle; GO:0032890 regulation of organic acid transport; GO:0017038 protein import; GO:0048869 cellular developmental process; GO:0051046 regulation of secretion; GO:0006796 phosphate-containing compound metabolic process; GO:0097746 regulation of blood vessel diameter; GO:0007165 signal transduction; GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger; GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling; GO:0051173 positive regulation of nitr"}},"GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0072562 blood microparticle; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0030546 receptor activator activity; GO:0008083 growth factor activity; GO:0048018 receptor agonist activity; GO:0005102 receptor binding; GO:0061134 peptidase regulator activity; GO:0005179 hormone activity; GO:0005515 protein binding; GO:0017080 sodium channel regulator activity; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0004871 signal transducer activity; GO:0004866 endopeptidase inhibitor activity; GO:0031703 type 2 angiotensin receptor binding; GO:0004867 serine-type endopeptidase inhibitor activity; GO:0030545 receptor regulator activity; GO:0030234 enzyme regulator activity; GO:0016247 channel regulator activity; GO:0005488 binding; GO:0030414 peptidase inhibitor activity; GO:0031702 type 1 angiotensin receptor binding; GO:0016176 superoxide-generating NADPH oxidase activator activity; GO:0061135 endopeptidase regulator activity; GO:0001664 G-protein coupled receptor binding; GO:0031701 angiotensin receptor binding; GO:0008047 enzyme activator activity; ","K09821","AGT; angiotensinogen","hsa04924 Renin secretion - Homo sapiens (human); hsa04614 Renin-angiotensin system - Homo sapiens (human); ","IPR033834; IPR023796; ","Angiotensinogen serpin domain; Serpin domain; \r"]
["P01023","Alpha-2-macroglobulin OS=Homo sapiens OX=9606 GN=A2M","A2M",163.29,323.31,44.5,53,159,49,0.885,0.902,0.869,1.079,1.101,1.12,1.242,0.00014,"extracellular\r","GO:0065008 regulation of biological quality; GO:0007596 blood coagulation; GO:0023051 regulation of signaling; GO:0048869 cellular developmental process; GO:0002698 negative regulation of immune effector process; GO:1903318 negative regulation of protein maturation; GO:0045916 negative regulation of complement activation; GO:0044699 single-organism process; GO:0031347 regulation of defense response; GO:0051234 establishment of localization; GO:0009611 response to wounding; GO:0010466 negative regulation of peptidase activity; GO:0008152 metabolic process; GO:0010646 regulation of cell communication; GO:0045088 regulation of innate immune response; GO:0044093 positive regulation of molecular function; GO:0022617 extracellular matrix disassembly; GO:0050777 negative regulation of immune response; GO:0030198 extracellular matrix organization; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0002697 regulation of immune effector process; GO:0051056 regulation of small GTPase mediated signal transduction; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0032502 developmental process; GO:0052548 regulation of endopeptidase activity; GO:0010468 regulation of gene expression; GO:0001868 regulation of complement activation, lectin pathway; GO:0007597 blood coagulation, intrinsic pathway; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0050776 regulation of immune response; GO:0002683 negative regulation of immune system process; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0051336 regulation of hydrolase activity; GO:0032940 secretion by cell; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0048583 regulation of response to stimulus; GO:0001869 negative regulation of complement activation, lectin pathway; GO:0043087 regulation of GTPase activity; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0002682 regulation of immune system process; GO:0044092 negative regulation of molecular function; GO:1903317 regulation of protein maturation; GO:0050817 coagulation; GO:0052547 regulation of peptidase activity; GO:0050794 regulation of cellular process; GO:0030449 regulation of complement activation; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:2000257 regulation of protein activation cascade; GO:0010951 negative regulation of endopeptidase activity; GO:0060255 regulation of macromolecule metabolic process; GO:0002920 regulation of humoral immune response; GO:0010955 negative regulation of protein processing; GO:0002673 regulation of acute inflammatory response; GO:0002576 platelet degranulation; GO:0080134 regulation of response to stress; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0002921 negative regulation of humoral immune response; GO:0050896 response to stimulus; GO:0051346 negative regulation of hydrolase activity; GO:0007599 hemostasis; GO:0071704 organic substance metabolic process; GO:2000258 negative regulation of protein activation cascade; GO:0030154 cell differentiation; GO:1902578 single-organism localization; GO:0051345 positive regulation of hydrolase activity; GO:0043062 extracellular structure organization; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:0031348 negative regulation of defense response; GO:0045861 negative regulation of proteolysis; GO:1902531 regulation of intracellular signal transduction; GO:0050878 regulation of body fluid levels; GO:0006950 response to stress; GO:0010629 negative regulation of gene expression; GO:0043547 positive regulation of GTPase activity; GO:0016192 vesicle-mediated transport; GO:0032101 regulation of response to external stimulus; GO:0072376 protein activation cascade; GO:0048585 negative regulation of response to stimulus; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0072378 blood coagulation, fibrin clot formation; GO:0043085 positive regulation of catalytic activity; GO:0045824 negative regulation of innate immune response; GO:0045055 regulated exocytosis; GO:0042060 wound healing; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0070613 regulation of protein processing; GO:0050727 regulation of inflammatory response; GO:0048863 stem cell differentiation; GO:0022411 cellular component disassembly; GO:0051248 negative regulation of protein metabolic process; GO:0051179 localization; GO:0071840 cellular component organization or biogenesis; GO:0006887 exocytosis; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0072562 blood microparticle; GO:0060205 cytoplasmic vesicle lumen; GO:0031093 platelet alpha granule lumen; GO:0031091 platelet alpha granule; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005102 receptor binding; GO:0019838 growth factor binding; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0019966 interleukin-1 binding; GO:0030695 GTPase regulator activity; GO:0061134 peptidase regulator activity; GO:0019958 C-X-C chemokine binding; GO:0005515 protein binding; GO:0019956 chemokine binding; GO:0098772 molecular function regulator; GO:0004857 enzyme inhibitor activity; GO:0004866 endopeptidase inhibitor activity; GO:0048306 calcium-dependent protein binding; GO:0002020 protease binding; GO:0019955 cytokine binding; GO:0004867 serine-type endopeptidase inhibitor activity; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0030414 peptidase inhibitor activity; GO:0043120 tumor necrosis factor binding; GO:0061135 endopeptidase regulator activity; GO:0008047 enzyme activator activity; GO:0019959 interleukin-8 binding; GO:0019899 enzyme binding; GO:0005096 GTPase activator activity; ","K03910","A2M; alpha-2-macroglobulin","hsa04610 Complement and coagulation cascades - Homo sapiens (human); ","IPR002890; IPR011625; IPR009048; IPR014756; IPR008930; IPR001599; IPR019565; IPR011626; ","\"Alpha-2-macroglobulin, N-terminal; Alpha-2-macroglobulin, N-terminal 2; Alpha-macroglobulin, receptor-binding; Immunoglobulin E-set; Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid; Alpha-2-macroglobulin; Alpha-2-macroglobulin, thiol-ester bond-forming; Alpha-macroglobulin complement component; \"\r"]
["P01024","Complement C3 OS=Homo sapiens OX=9606 GN=C3","C3",187.15,323.31,55.8,87,254,87,0.97,0.97,0.961,1.026,1.033,1.031,1.065,6.49e-05,"endoplasmic reticulum\r","GO:0044700 single organism signaling; GO:0060627 regulation of vesicle-mediated transport; GO:0065008 regulation of biological quality; GO:0016064 immunoglobulin mediated immune response; GO:0045321 leukocyte activation; GO:0032270 positive regulation of cellular protein metabolic process; GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:2000259 positive regulation of protein activation cascade; GO:0044255 cellular lipid metabolic process; GO:0019216 regulation of lipid metabolic process; GO:0031347 regulation of defense response; GO:0044237 cellular metabolic process; GO:0006956 complement activation; GO:0010466 negative regulation of peptidase activity; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0006958 complement activation, classical pathway; GO:1904018 positive regulation of vasculature development; GO:0032787 monocarboxylic acid metabolic process; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0002883 regulation of hypersensitivity; GO:0052548 regulation of endopeptidase activity; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0051174 regulation of phosphorus metabolic process; GO:0002443 leukocyte mediated immunity; GO:0050729 positive regulation of inflammatory response; GO:0080090 regulation of primary metabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0001969 regulation of activation of membrane attack complex; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0002889 regulation of immunoglobulin mediated immune response; GO:0051336 regulation of hydrolase activity; GO:0044710 single-organism metabolic process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0046890 regulation of lipid biosynthetic process; GO:0048583 regulation of response to stimulus; GO:0002892 regulation of type II hypersensitivity; GO:0010604 positive regulation of macromolecule metabolic process; GO:0045765 regulation of angiogenesis; GO:0002682 regulation of immune system process; GO:1903317 regulation of protein maturation; GO:0002821 positive regulation of adaptive immune response; GO:0051094 positive regulation of developmental process; GO:0043436 oxoacid metabolic process; GO:0050794 regulation of cellular process; GO:0030449 regulation of complement activation; GO:2000257 regulation of protein activation cascade; GO:0010951 negative regulation of endopeptidase activity; GO:0002283 neutrophil activation involved in immune response; GO:0001819 positive regulation of cytokine production; GO:0031399 regulation of protein modification process; GO:0002920 regulation of humoral immune response; GO:0001970 positive regulation of activation of membrane attack complex; GO:0002886 regulation of myeloid leukocyte mediated immunity; GO:2000427 positive regulation of apoptotic cell clearance; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0002894 positive regulation of type II hypersensitivity; GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0051239 regulation of multicellular organismal process; GO:0019724 B cell mediated immunity; GO:0031349 positive regulation of defense response; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0090207 regulation of triglyceride metabolic process; GO:0002449 lymphocyte mediated immunity; GO:0009966 regulation of signal transduction; GO:0050778 positive regulation of immune response; GO:0002253 activation of immune response; GO:0045861 negative regulation of proteolysis; GO:0010575 positive regulation of vascular endothelial growth factor production; GO:0030100 regulation of endocytosis; GO:0006950 response to stress; GO:0002864 regulation of acute inflammatory response to antigenic stimulus; GO:0010884 positive regulation of lipid storage; GO:0016192 vesicle-mediated transport; GO:0050766 positive regulation of phagocytosis; GO:0072376 protein activation cascade; GO:0002376 immune system process; GO:0032101 regulation of response to external stimulus; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0002263 cell activation involved in immune response; GO:0009892 negative regulation of metabolic process; GO:0007186 G-protein coupled receptor signaling pathway; GO:0045055 regulated exocytosis; GO:0051247 positive regulation of protein metabolic process; GO:0010883 regulation of lipid storage; GO:0006957 complement activation, alternative pathway; GO:0031325 positive regulation of cellular metabolic process; GO:0070613 regulation of protein processing; GO:0001775 cell activation; GO:0001798 positive regulation of type IIa hypersensitivity; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0010866 regulation of triglyceride biosynthetic process; GO:0051179 localization; GO:0006955 immune response; GO:0048584 positive regulation of response to stimulus; GO:0050793 regulation of developmental process; GO:0006887 exocytosis; GO:0002675 positive regulation of acute inflammatory response; GO:2000425 regulation of apoptotic cell clearance; GO:0002922 positive regulation of humoral immune response; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0010574 regulation of vascular endothelial growth factor production; GO:0051234 establishment of localization; GO:0002863 positive regulation of inflammatory response to antigenic stimulus; GO:0051130 positive regulation of cellular component organization; GO:0002888 positive regulation of myeloid leukocyte mediated immunity; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0002819 regulation of adaptive immune response; GO:0032103 positive regulation of response to external stimulus; GO:0002250 adaptive immune response; GO:0010827 regulation of glucose transport; GO:0002697 regulation of immune effector process; GO:0050764 regulation of phagocytosis; GO:0002708 positive regulation of lymphocyte mediated immunity; GO:0002274 myeloid leukocyte activation; GO:0006629 lipid metabolic process; GO:0010468 regulation of gene expression; GO:0045937 positive regulation of phosphate metabolic process; GO:0031326 regulation of cellular biosynthetic process; GO:0001796 regulation of type IIa hypersensitivity; GO:0002446 neutrophil mediated immunity; GO:0010828 positive regulation of glucose transport; GO:0008277 regulation of G-protein coupled receptor protein signaling pathway; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0051050 positive regulation of transport; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0002705 positive regulation of leukocyte mediated immunity; GO:0032940 secretion by cell; GO:0006954 inflammatory response; GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0043299 leukocyte degranulation; GO:0019220 regulation of phosphate metabolic process; GO:0045917 positive regulation of complement activation; GO:0006952 defense response; GO:0006082 organic acid metabolic process; GO:0052547 regulation of peptidase activity; GO:0002891 positive regulation of immunoglobulin mediated immune response; GO:2000026 regulation of multicellular organismal development; GO:1903319 positive regulation of protein maturation; GO:0002885 positive regulation of hypersensitivity; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0045807 positive regulation of endocytosis; GO:0002673 regulation of acute inflammatory response; GO:0006959 humoral immune response; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0002706 regulation of lymphocyte mediated immunity; GO:0045766 positive regulation of angiogenesis; GO:0051346 negative regulation of hydrolase activity; GO:0045087 innate immune response; GO:0071704 organic substance metabolic process; GO:0045862 positive regulation of proteolysis; GO:0023056 positive regulation of signaling; GO:0006508 proteolysis; GO:0010647 positive regulation of cell communication; GO:0036230 granulocyte activation; GO:0002714 positive regulation of B cell mediated immunity; GO:0009987 cellular process; GO:0051049 regulation of transport; GO:0002699 positive regulation of immune effector process; GO:0002712 regulation of B cell mediated immunity; GO:0001932 regulation of protein phosphorylation; GO:1901342 regulation of vasculature development; GO:0002866 positive regulation of acute inflammatory response to antigenic stimulus; GO:0031401 positive regulation of protein modification process; GO:0006631 fatty acid metabolic process; GO:0043312 neutrophil degranulation; GO:0001934 positive regulation of protein phosphorylation; GO:0048518 positive regulation of biological process; GO:0002703 regulation of leukocyte mediated immunity; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0010954 positive regulation of protein processing; GO:0051246 regulation of protein metabolic process; GO:0002684 positive regulation of immune system process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0019752 carboxylic acid metabolic process; GO:0050727 regulation of inflammatory response; GO:0051248 negative regulation of protein metabolic process; GO:0001817 regulation of cytokine production; GO:0009967 positive regulation of signal transduction; GO:0051128 regulation of cellular component organization; GO:0002861 regulation of inflammatory response to antigenic stimulus; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0034774 secretory granule lumen; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0042582 azurophil granule; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0072562 blood microparticle; GO:0060205 cytoplasmic vesicle lumen; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0008233 peptidase activity; GO:0005102 receptor binding; GO:0008236 serine-type peptidase activity; GO:0061134 peptidase regulator activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0004866 endopeptidase inhibitor activity; GO:0031715 C5L2 anaphylatoxin chemotactic receptor binding; GO:0031714 C5a anaphylatoxin chemotactic receptor binding; GO:0004175 endopeptidase activity; GO:0004252 serine-type endopeptidase activity; GO:0030234 enzyme regulator activity; GO:0003824 catalytic activity; GO:0017171 serine hydrolase activity; GO:0005488 binding; GO:0030414 peptidase inhibitor activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0061135 endopeptidase regulator activity; GO:0001664 G-protein coupled receptor binding; ","K03990","C3; complement component 3","hsa05142 Chagas disease (American trypanosomiasis) - Homo sapiens (human); hsa05322 Systemic lupus erythematosus - Homo sapiens (human); hsa05152 Tuberculosis - Homo sapiens (human); hsa05150 Staphylococcus aureus infection - Homo sapiens (human); hsa05168 Herpes simplex infection - Homo sapiens (human); hsa05140 Leishmaniasis - Homo sapiens (human); hsa05167 Kaposi's sarcoma-associated herpesvirus infection - Homo sapiens (human); hsa05203 Viral carcinogenesis - Homo sapiens (human); hsa05134 Legionellosis - Homo sapiens (human); hsa05133 Pertussis - Homo sapiens (human); hsa04610 Complement and coagulation cascades - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); ","IPR008993; IPR001599; IPR011626; IPR000020; IPR002890; IPR011625; IPR009048; IPR001134; IPR001840; IPR018933; IPR008930; IPR019565; IPR018081; ","\"Tissue inhibitor of metalloproteinases-like, OB-fold; Alpha-2-macroglobulin; Alpha-macroglobulin complement component; Anaphylatoxin/fibulin; Alpha-2-macroglobulin, N-terminal; Alpha-2-macroglobulin, N-terminal 2; Alpha-macroglobulin, receptor-binding; Netrin domain; Anaphylatoxin, complement system domain; Netrin module, non-TIMP type; Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid; Alpha-2-macroglobulin, thiol-ester bond-forming; Anaphylatoxin, complement system; \"\r"]
["P01031","Complement C5 OS=Homo sapiens OX=9606 GN=C5","C5",188.3,133.8,18.7,32,42,29,0.99,0.956,0.953,1.041,1.024,1.05,1.075,0.00724,"endoplasmic reticulum\r","GO:0044700 single organism signaling; GO:0016064 immunoglobulin mediated immune response; GO:0032270 positive regulation of cellular protein metabolic process; GO:0007166 cell surface receptor signaling pathway; GO:0043009 chordate embryonic development; GO:0031347 regulation of defense response; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0006956 complement activation; GO:0009605 response to external stimulus; GO:0010466 negative regulation of peptidase activity; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0032102 negative regulation of response to external stimulus; GO:0006958 complement activation, classical pathway; GO:1904018 positive regulation of vasculature development; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0051347 positive regulation of transferase activity; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009790 embryo development; GO:0052548 regulation of endopeptidase activity; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0050707 regulation of cytokine secretion; GO:0048870 cell motility; GO:0031323 regulation of cellular metabolic process; GO:0043086 negative regulation of catalytic activity; GO:2000146 negative regulation of cell motility; GO:0032501 multicellular organismal process; GO:0006935 chemotaxis; GO:0050776 regulation of immune response; GO:0051336 regulation of hydrolase activity; GO:0001701 in utero embryonic development; GO:0002689 negative regulation of leukocyte chemotaxis; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0050714 positive regulation of protein secretion; GO:0010604 positive regulation of macromolecule metabolic process; GO:0045765 regulation of angiogenesis; GO:0042330 taxis; GO:0051223 regulation of protein transport; GO:0002682 regulation of immune system process; GO:0002685 regulation of leukocyte migration; GO:1903317 regulation of protein maturation; GO:0051094 positive regulation of developmental process; GO:0051047 positive regulation of secretion; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0030449 regulation of complement activation; GO:2000257 regulation of protein activation cascade; GO:0019835 cytolysis; GO:0010951 negative regulation of endopeptidase activity; GO:0001819 positive regulation of cytokine production; GO:0031399 regulation of protein modification process; GO:0002920 regulation of humoral immune response; GO:0071902 positive regulation of protein serine/threonine kinase activity; GO:0060326 cell chemotaxis; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0051239 regulation of multicellular organismal process; GO:0019724 B cell mediated immunity; GO:0032147 activation of protein kinase activity; GO:2000145 regulation of cell motility; GO:0051338 regulation of transferase activity; GO:1905522 negative regulation of macrophage migration; GO:0007275 multicellular organism development; GO:0032880 regulation of protein localization; GO:0090196 regulation of chemokine secretion; GO:0002449 lymphocyte mediated immunity; GO:0009966 regulation of signal transduction; GO:0050778 positive regulation of immune response; GO:0002253 activation of immune response; GO:0045861 negative regulation of proteolysis; GO:1902531 regulation of intracellular signal transduction; GO:0010575 positive regulation of vascular endothelial growth factor production; GO:0006950 response to stress; GO:0051270 regulation of cellular component movement; GO:0072376 protein activation cascade; GO:0002376 immune system process; GO:0030334 regulation of cell migration; GO:0032101 regulation of response to external stimulus; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0007186 G-protein coupled receptor signaling pathway; GO:0051247 positive regulation of protein metabolic process; GO:0043406 positive regulation of MAP kinase activity; GO:1904951 positive regulation of establishment of protein localization; GO:0006957 complement activation, alternative pathway; GO:0030336 negative regulation of cell migration; GO:0031325 positive regulation of cellular metabolic process; GO:0070613 regulation of protein processing; GO:0006928 movement of cell or subcellular component; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0048584 positive regulation of response to stimulus; GO:0006955 immune response; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0010760 negative regulation of macrophage chemotaxis; GO:0051674 localization of cell; GO:0023051 regulation of signaling; GO:0050922 negative regulation of chemotaxis; GO:1902533 positive regulation of intracellular signal transduction; GO:0051046 regulation of secretion; GO:0044699 single-organism process; GO:0010574 regulation of vascular endothelial growth factor production; GO:0040013 negative regulation of locomotion; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0032642 regulation of chemokine production; GO:0002250 adaptive immune response; GO:0033674 positive regulation of kinase activity; GO:0002697 regulation of immune effector process; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0045937 positive regulation of phosphate metabolic process; GO:0002688 regulation of leukocyte chemotaxis; GO:0048522 positive regulation of cellular process; GO:1903530 regulation of secretion by cell; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0051050 positive regulation of transport; GO:0002683 negative regulation of immune system process; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0042221 response to chemical; GO:1903532 positive regulation of secretion by cell; GO:0006954 inflammatory response; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0040011 locomotion; GO:0006952 defense response; GO:0052547 regulation of peptidase activity; GO:0048856 anatomical structure development; GO:0050715 positive regulation of cytokine secretion; GO:0043549 regulation of kinase activity; GO:0051222 positive regulation of protein transport; GO:0032722 positive regulation of chemokine production; GO:0051271 negative regulation of cellular component movement; GO:2000026 regulation of multicellular organismal development; GO:0045859 regulation of protein kinase activity; GO:0002686 negative regulation of leukocyte migration; GO:0016477 cell migration; GO:0002252 immune effector process; GO:0043405 regulation of MAP kinase activity; GO:0060255 regulation of macromolecule metabolic process; GO:0002673 regulation of acute inflammatory response; GO:0006959 humoral immune response; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0045766 positive regulation of angiogenesis; GO:0045087 innate immune response; GO:0051346 negative regulation of hydrolase activity; GO:0070201 regulation of establishment of protein localization; GO:0071704 organic substance metabolic process; GO:0043408 regulation of MAPK cascade; GO:0023056 positive regulation of signaling; GO:0010647 positive regulation of cell communication; GO:0050708 regulation of protein secretion; GO:0009987 cellular process; GO:1905521 regulation of macrophage migration; GO:0090197 positive regulation of chemokine secretion; GO:0051049 regulation of transport; GO:0009792 embryo development ending in birth or egg hatching; GO:0001932 regulation of protein phosphorylation; GO:1901342 regulation of vasculature development; GO:0031401 positive regulation of protein modification process; GO:0048585 negative regulation of response to stimulus; GO:0045860 positive regulation of protein kinase activity; GO:0001934 positive regulation of protein phosphorylation; GO:0050920 regulation of chemotaxis; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0000187 activation of MAPK activity; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0002684 positive regulation of immune system process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0050727 regulation of inflammatory response; GO:0051248 negative regulation of protein metabolic process; GO:0001817 regulation of cytokine production; GO:0009967 positive regulation of signal transduction; GO:0010758 regulation of macrophage chemotaxis; GO:0043410 positive regulation of MAPK cascade; GO:0040012 regulation of locomotion; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0031226 intrinsic component of plasma membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0098796 membrane protein complex; GO:0071944 cell periphery; GO:0046930 pore complex; GO:0098797 plasma membrane protein complex; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0044459 plasma membrane part; GO:0044464 cell part; GO:0044425 membrane part; GO:1903561 extracellular vesicle; GO:0005579 membrane attack complex; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0005102 receptor binding; GO:0061134 peptidase regulator activity; GO:0005126 cytokine receptor binding; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0004857 enzyme inhibitor activity; GO:0004866 endopeptidase inhibitor activity; GO:0008009 chemokine activity; GO:0005125 cytokine activity; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0042379 chemokine receptor binding; GO:0030414 peptidase inhibitor activity; GO:0001664 G-protein coupled receptor binding; GO:0061135 endopeptidase regulator activity; ","K03994","C5; complement component 5","hsa05322 Systemic lupus erythematosus - Homo sapiens (human); hsa05133 Pertussis - Homo sapiens (human); hsa04610 Complement and coagulation cascades - Homo sapiens (human); hsa05150 Staphylococcus aureus infection - Homo sapiens (human); hsa05168 Herpes simplex infection - Homo sapiens (human); hsa05020 Prion diseases - Homo sapiens (human); ","IPR008993; IPR001599; IPR011626; IPR000020; IPR002890; IPR011625; IPR009048; IPR001134; IPR001840; IPR018933; IPR008930; IPR018081; ","\"Tissue inhibitor of metalloproteinases-like, OB-fold; Alpha-2-macroglobulin; Alpha-macroglobulin complement component; Anaphylatoxin/fibulin; Alpha-2-macroglobulin, N-terminal; Alpha-2-macroglobulin, N-terminal 2; Alpha-macroglobulin, receptor-binding; Netrin domain; Anaphylatoxin, complement system domain; Netrin module, non-TIMP type; Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid; Anaphylatoxin, complement system; \"\r"]
["P01033","Metalloproteinase inhibitor 1 OS=Homo sapiens OX=9606 GN=TIMP1","TIMP1",23.171,5.4516,9.7,2,2,2,1.089,0.974,0.99,1.029,0.893,1.037,0.969,0.617,"extracellular\r","GO:0051093 negative regulation of developmental process; GO:0010941 regulation of cell death; GO:0051216 cartilage development; GO:0023051 regulation of signaling; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:1901163 regulation of trophoblast cell migration; GO:0051234 establishment of localization; GO:0009611 response to wounding; GO:0040013 negative regulation of locomotion; GO:0010466 negative regulation of peptidase activity; GO:0010646 regulation of cell communication; GO:0032879 regulation of localization; GO:0022617 extracellular matrix disassembly; GO:0009719 response to endogenous stimulus; GO:0030198 extracellular matrix organization; GO:0061448 connective tissue development; GO:1901652 response to peptide; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0052548 regulation of endopeptidase activity; GO:0032502 developmental process; GO:0009888 tissue development; GO:0034097 response to cytokine; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:2000146 negative regulation of cell motility; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0006810 transport; GO:0010243 response to organonitrogen compound; GO:2000241 regulation of reproductive process; GO:0048513 animal organ development; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0043434 response to peptide hormone; GO:0051336 regulation of hydrolase activity; GO:0032940 secretion by cell; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0007568 aging; GO:0048583 regulation of response to stimulus; GO:2000242 negative regulation of reproductive process; GO:1901698 response to nitrogen compound; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0052547 regulation of peptidase activity; GO:0060548 negative regulation of cell death; GO:1905048 regulation of metallopeptidase activity; GO:0048856 anatomical structure development; GO:0001501 skeletal system development; GO:0051271 negative regulation of cellular component movement; GO:2000026 regulation of multicellular organismal development; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0010951 negative regulation of endopeptidase activity; GO:0043069 negative regulation of programmed cell death; GO:0042127 regulation of cell proliferation; GO:0042177 negative regulation of protein catabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:1901700 response to oxygen-containing compound; GO:0043067 regulation of programmed cell death; GO:1905049 negative regulation of metallopeptidase activity; GO:0002576 platelet degranulation; GO:1901164 negative regulation of trophoblast cell migration; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:0051346 negative regulation of hydrolase activity; GO:2001044 regulation of integrin-mediated signaling pathway; GO:1902578 single-organism localization; GO:0043066 negative regulation of apoptotic process; GO:0051043 regulation of membrane protein ectodomain proteolysis; GO:0043062 extracellular structure organization; GO:2000145 regulation of cell motility; GO:0009895 negative regulation of catabolic process; GO:0042176 regulation of protein catabolic process; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:0045861 negative regulation of proteolysis; GO:0006950 response to stress; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0043900 regulation of multi-organism process; GO:0030334 regulation of cell migration; GO:0010033 response to organic substance; GO:0030162 regulation of proteolysis; GO:0048518 positive regulation of biological process; GO:0009892 negative regulation of metabolic process; GO:0043901 negative regulation of multi-organism process; GO:0031330 negative regulation of cellular catabolic process; GO:0045055 regulated exocytosis; GO:0042060 wound healing; GO:0030336 negative regulation of cell migration; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0001775 cell activation; GO:0022411 cellular component disassembly; GO:0051248 negative regulation of protein metabolic process; GO:0009725 response to hormone; GO:0040012 regulation of locomotion; GO:0051179 localization; GO:0051045 negative regulation of membrane protein ectodomain proteolysis; GO:0050793 regulation of developmental process; GO:0042981 regulation of apoptotic process; GO:0008284 positive regulation of cell proliferation; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:0006887 exocytosis; ","GO:0034774 secretory granule lumen; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044420 extracellular matrix component; GO:0044422 organelle part; GO:0005604 basement membrane; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0043226 organelle; GO:0031012 extracellular matrix; GO:0060205 cytoplasmic vesicle lumen; GO:0005578 proteinaceous extracellular matrix; GO:0031093 platelet alpha granule lumen; GO:0031091 platelet alpha granule; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0008083 growth factor activity; GO:0005102 receptor binding; GO:0043167 ion binding; GO:0061134 peptidase regulator activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0004857 enzyme inhibitor activity; GO:0004866 endopeptidase inhibitor activity; GO:0002020 protease binding; GO:0005125 cytokine activity; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0030414 peptidase inhibitor activity; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0008191 metalloendopeptidase inhibitor activity; GO:0061135 endopeptidase regulator activity; GO:0019899 enzyme binding; ","K16451","TIMP1; metallopeptidase inhibitor 1","hsa04066 HIF-1 signaling pathway - Homo sapiens (human); ","IPR008993; IPR001134; IPR027465; ","\"Tissue inhibitor of metalloproteinases-like, OB-fold; Netrin domain; Proteinase inhibitor I35b (TIMP), C-terminal; \"\r"]
["P01034","Cystatin-C OS=Homo sapiens OX=9606 GN=CST3","CST3",15.799,48.355,36.3,4,6,4,1.002,1.059,1.01,1.032,0.982,0.967,0.971,0.318,"extracellular\r","GO:0010941 regulation of cell death; GO:0045321 leukocyte activation; GO:0048732 gland development; GO:0060311 negative regulation of elastin catabolic process; GO:0022414 reproductive process; GO:0007420 brain development; GO:0007566 embryo implantation; GO:0008584 male gonad development; GO:0009891 positive regulation of biosynthetic process; GO:0010713 negative regulation of collagen metabolic process; GO:0044237 cellular metabolic process; GO:0007622 rhythmic behavior; GO:0007610 behavior; GO:0009605 response to external stimulus; GO:1903054 negative regulation of extracellular matrix organization; GO:0010466 negative regulation of peptidase activity; GO:0008152 metabolic process; GO:0060313 negative regulation of blood vessel remodeling; GO:0044706 multi-multicellular organism process; GO:0044702 single organism reproductive process; GO:0010710 regulation of collagen catabolic process; GO:0009743 response to carbohydrate; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0007399 nervous system development; GO:0052548 regulation of endopeptidase activity; GO:0051716 cellular response to stimulus; GO:0014070 response to organic cyclic compound; GO:0002064 epithelial cell development; GO:0002443 leukocyte mediated immunity; GO:0003006 developmental process involved in reproduction; GO:0051054 positive regulation of DNA metabolic process; GO:0080090 regulation of primary metabolic process; GO:0010711 negative regulation of collagen catabolic process; GO:0031329 regulation of cellular catabolic process; GO:0000302 response to reactive oxygen species; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0060008 Sertoli cell differentiation; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0048513 animal organ development; GO:0051336 regulation of hydrolase activity; GO:0007417 central nervous system development; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0030431 sleep; GO:0060548 negative regulation of cell death; GO:0097435 supramolecular fiber organization; GO:0044708 single-organism behavior; GO:0030855 epithelial cell differentiation; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0000003 reproduction; GO:0033554 cellular response to stress; GO:0044707 single-multicellular organism process; GO:0010951 negative regulation of endopeptidase activity; GO:0002283 neutrophil activation involved in immune response; GO:0042127 regulation of cell proliferation; GO:0006275 regulation of DNA replication; GO:0009628 response to abiotic stimulus; GO:1901700 response to oxygen-containing compound; GO:0043067 regulation of programmed cell death; GO:0044267 cellular protein metabolic process; GO:0008406 gonad development; GO:0032355 response to estradiol; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0022410 circadian sleep/wake cycle process; GO:0051239 regulation of multicellular organismal process; GO:0042493 response to drug; GO:0007565 female pregnancy; GO:0001654 eye development; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0010715 regulation of extracellular matrix disassembly; GO:0009889 regulation of biosynthetic process; GO:0045740 positive regulation of DNA replication; GO:0070482 response to oxygen levels; GO:0051171 regulation of nitrogen compound metabolic process; GO:0007548 sex differentiation; GO:0042176 regulation of protein catabolic process; GO:0007275 multicellular organism development; GO:0061458 reproductive system development; GO:0050802 circadian sleep/wake cycle, sleep; GO:0060310 regulation of elastin catabolic process; GO:0045861 negative regulation of proteolysis; GO:0006950 response to stress; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0034104 negative regulation of tissue remodeling; GO:1903018 regulation of glycoprotein metabolic process; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0002263 cell activation involved in immune response; GO:0009892 negative regulation of metabolic process; GO:0031330 negative regulation of cellular catabolic process; GO:0045055 regulated exocytosis; GO:0048678 response to axon injury; GO:0042542 response to hydrogen peroxide; GO:0031325 positive regulation of cellular metabolic process; GO:0060312 regulation of blood vessel remodeling; GO:0001775 cell activation; GO:0012501 programmed cell death; GO:0036293 response to decreased oxygen levels; GO:0046546 development of primary male sexual characteristics; GO:0051179 localization; GO:0006955 immune response; GO:0031328 positive regulation of cellular biosynthetic process; GO:0007423 sensory organ development; GO:0010712 regulation of collagen metabolic process; GO:0050793 regulation of developmental process; GO:0008284 positive regulation of cell proliferation; GO:0006887 exocytosis; GO:0051093 negative regulation of developmental process; GO:0044246 regulation of multicellular organismal metabolic process; GO:0048869 cellular developmental process; GO:0051129 negative regulation of cellular component organization; GO:0044699 single-organism process; GO:0051241 negative regulation of multicellular organismal process; GO:0034103 regulation of tissue remodeling; GO:0010716 negative regulation of extracellular matrix disassembly; GO:0051234 establishment of localization; GO:0009611 response to wounding; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0006915 apoptotic process; GO:0006979 response to oxidative stress; GO:0060322 head development; GO:0034599 cellular response to oxidative stress; GO:0010035 response to inorganic substance; GO:0048512 circadian behavior; GO:1903019 negative regulation of glycoprotein metabolic process; GO:0070887 cellular response to chemical stimulus; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0034614 cellular response to reactive oxygen species; GO:0009888 tissue development; GO:0031326 regulation of cellular biosynthetic process; GO:0002446 neutrophil mediated immunity; GO:0009636 response to toxic substance; GO:0048608 reproductive structure development; GO:0048522 positive regulation of cellular process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0007623 circadian rhythm; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0051052 regulation of DNA metabolic process; GO:0032940 secretion by cell; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0006952 defense response; GO:0043299 leukocyte degranulation; GO:0052547 regulation of peptidase activity; GO:0048856 anatomical structure development; GO:0016043 cellular component organization; GO:0042177 negative regulation of protein catabolic process; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0046661 male sex differentiation; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044252 negative regulation of multicellular organismal metabolic process; GO:0007431 salivary gland development; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0051346 negative regulation of hydrolase activity; GO:0071704 organic substance metabolic process; GO:0070301 cellular response to hydrogen peroxide; GO:0009991 response to extracellular stimulus; GO:0033993 response to lipid; GO:0030154 cell differentiation; GO:0001666 response to hypoxia; GO:0042747 circadian sleep/wake cycle, REM sleep; GO:0009895 negative regulation of catabolic process; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0045137 development of primary sexual characteristics; GO:0042745 circadian sleep/wake cycle; GO:0035272 exocrine system development; GO:1903053 regulation of extracellular matrix organization; GO:0010556 regulation of macromolecule biosynthetic process; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:1901701 cellular response to oxygen-containing compound; GO:0008219 cell death; GO:0060009 Sertoli cell development; GO:0048511 rhythmic process; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0044703 multi-organism reproductive process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0051248 negative regulation of protein metabolic process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0031667 response to nutrient levels; GO:0051128 regulation of cellular component organization; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0043025 neuronal cell body; GO:0044433 cytoplasmic vesicle part; GO:0099080 supramolecular complex; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005604 basement membrane; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031965 nuclear membrane; GO:0005622 intracellular; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0005771 multivesicular body; GO:0097458 neuron part; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0042995 cell projection; GO:0005770 late endosome; GO:0031967 organelle envelope; GO:0005576 extracellular region; GO:0099081 supramolecular polymer; GO:0030424 axon; GO:0031012 extracellular matrix; GO:0043231 intracellular membrane-bounded organelle; GO:0031975 envelope; GO:0005773 vacuole; GO:0043230 extracellular organelle; GO:1904724 tertiary granule lumen; GO:0005783 endoplasmic reticulum; GO:0005615 extracellular space; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0099512 supramolecular fiber; GO:0044420 extracellular matrix component; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043292 contractile fiber; GO:0048471 perinuclear region of cytoplasm; GO:0005768 endosome; GO:0030141 secretory granule; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0005635 nuclear envelope; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0070820 tertiary granule; GO:0012505 endomembrane system; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0005634 nucleus; GO:0005578 proteinaceous extracellular matrix; GO:0044297 cell body; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0002020 protease binding; GO:0001540 beta-amyloid binding; GO:0042802 identical protein binding; GO:0030234 enzyme regulator activity; GO:0042277 peptide binding; GO:0005488 binding; GO:0030414 peptidase inhibitor activity; GO:0061134 peptidase regulator activity; GO:0005515 protein binding; GO:0061135 endopeptidase regulator activity; GO:0033218 amide binding; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0004866 endopeptidase inhibitor activity; GO:0019899 enzyme binding; GO:0004869 cysteine-type endopeptidase inhibitor activity; ","K13899","CST3; cystatin-C","hsa04970 Salivary secretion - Homo sapiens (human); ","IPR000010; ","Cystatin domain; \r"]
["P01040","Cystatin-A OS=Homo sapiens OX=9606 GN=CSTA","CSTA",11.006,60.564,59.2,5,11,5,0.779,0.748,0.806,1.189,1.212,1.24,1.561,5.81e-05,"cytoplasm\r","GO:0031424 keratinization; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0022610 biological adhesion; GO:0009913 epidermal cell differentiation; GO:0010466 negative regulation of peptidase activity; GO:0016337 single organismal cell-cell adhesion; GO:0008152 metabolic process; GO:0007155 cell adhesion; GO:0008544 epidermis development; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0052548 regulation of endopeptidase activity; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0043588 skin development; GO:0030216 keratinocyte differentiation; GO:0009888 tissue development; GO:0080090 regulation of primary metabolic process; GO:0070268 cornification; GO:0098609 cell-cell adhesion; GO:0044763 single-organism cellular process; GO:0031323 regulation of cellular metabolic process; GO:0043086 negative regulation of catalytic activity; GO:0032501 multicellular organismal process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0051336 regulation of hydrolase activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0098602 single organism cell adhesion; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0006464 cellular protein modification process; GO:0044092 negative regulation of molecular function; GO:0036211 protein modification process; GO:0052547 regulation of peptidase activity; GO:0048856 anatomical structure development; GO:0030855 epithelial cell differentiation; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0010951 negative regulation of endopeptidase activity; GO:0060255 regulation of macromolecule metabolic process; GO:0044267 cellular protein metabolic process; GO:0018149 peptide cross-linking; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0051346 negative regulation of hydrolase activity; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0045861 negative regulation of proteolysis; GO:0048731 system development; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0008219 cell death; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0051248 negative regulation of protein metabolic process; GO:0012501 programmed cell death; GO:0043412 macromolecule modification; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0031012 extracellular matrix; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0001533 cornified envelope; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0030674 protein binding, bridging; GO:0061134 peptidase regulator activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0004857 enzyme inhibitor activity; GO:0004866 endopeptidase inhibitor activity; GO:0004869 cysteine-type endopeptidase inhibitor activity; GO:0002020 protease binding; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0030414 peptidase inhibitor activity; GO:0061135 endopeptidase regulator activity; GO:0060090 binding, bridging; GO:0005198 structural molecule activity; GO:0019899 enzyme binding; ","K13907",null,null,"IPR000010; ","Cystatin domain; \r"]
["P01042","Kininogen-1 OS=Homo sapiens OX=9606 GN=KNG1","KNG1",71.957,164.97,31.4,22,51,22,1.027,1.038,1.017,1.003,0.957,0.99,0.957,0.0444,"extracellular\r","GO:0010941 regulation of cell death; GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0072503 cellular divalent inorganic cation homeostasis; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0051234 establishment of localization; GO:0097746 regulation of blood vessel diameter; GO:0009611 response to wounding; GO:0010466 negative regulation of peptidase activity; GO:0008152 metabolic process; GO:0032102 negative regulation of response to external stimulus; GO:0055065 metal ion homeostasis; GO:1900046 regulation of hemostasis; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0052548 regulation of endopeptidase activity; GO:0050801 ion homeostasis; GO:0007597 blood coagulation, intrinsic pathway; GO:0080090 regulation of primary metabolic process; GO:0055074 calcium ion homeostasis; GO:0098771 inorganic ion homeostasis; GO:0044763 single-organism cellular process; GO:0019725 cellular homeostasis; GO:0048522 positive regulation of cellular process; GO:0031323 regulation of cellular metabolic process; GO:0043086 negative regulation of catalytic activity; GO:0032501 multicellular organismal process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0006874 cellular calcium ion homeostasis; GO:1903035 negative regulation of response to wounding; GO:0035296 regulation of tube diameter; GO:0010942 positive regulation of cell death; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0051336 regulation of hydrolase activity; GO:0032940 secretion by cell; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0006954 inflammatory response; GO:0048583 regulation of response to stimulus; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0006952 defense response; GO:0050817 coagulation; GO:0003013 circulatory system process; GO:0052547 regulation of peptidase activity; GO:0072507 divalent inorganic cation homeostasis; GO:0043068 positive regulation of programmed cell death; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0010951 negative regulation of endopeptidase activity; GO:0007162 negative regulation of cell adhesion; GO:0050880 regulation of blood vessel size; GO:0060255 regulation of macromolecule metabolic process; GO:0030003 cellular cation homeostasis; GO:0051480 regulation of cytosolic calcium ion concentration; GO:0030193 regulation of blood coagulation; GO:0043067 regulation of programmed cell death; GO:0002576 platelet degranulation; GO:0043065 positive regulation of apoptotic process; GO:0003018 vascular process in circulatory system; GO:0080134 regulation of response to stress; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:0055082 cellular chemical homeostasis; GO:0051239 regulation of multicellular organismal process; GO:0051346 negative regulation of hydrolase activity; GO:0007599 hemostasis; GO:0071704 organic substance metabolic process; GO:1900047 negative regulation of hemostasis; GO:0042592 homeostatic process; GO:1902578 single-organism localization; GO:0055080 cation homeostasis; GO:0008015 blood circulation; GO:0035150 regulation of tube size; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0045861 negative regulation of proteolysis; GO:0097755 positive regulation of blood vessel diameter; GO:0050878 regulation of body fluid levels; GO:0003008 system process; GO:0006950 response to stress; GO:0016192 vesicle-mediated transport; GO:0032101 regulation of response to external stimulus; GO:0072376 protein activation cascade; GO:0048585 negative regulation of response to stimulus; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0061045 negative regulation of wound healing; GO:0009892 negative regulation of metabolic process; GO:0072378 blood coagulation, fibrin clot formation; GO:0048518 positive regulation of biological process; GO:0030155 regulation of cell adhesion; GO:0042311 vasodilation; GO:0050818 regulation of coagulation; GO:0030195 negative regulation of blood coagulation; GO:0045055 regulated exocytosis; GO:0061041 regulation of wound healing; GO:0042060 wound healing; GO:0006873 cellular ion homeostasis; GO:0051246 regulation of protein metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0090066 regulation of anatomical structure size; GO:0006875 cellular metal ion homeostasis; GO:0007204 positive regulation of cytosolic calcium ion concentration; GO:0051179 localization; GO:1903034 regulation of response to wounding; GO:0050819 negative regulation of coagulation; GO:0042981 regulation of apoptotic process; GO:0006887 exocytosis; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0072562 blood microparticle; GO:0060205 cytoplasmic vesicle lumen; GO:0031093 platelet alpha granule lumen; GO:0031091 platelet alpha granule; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005102 receptor binding; GO:0061134 peptidase regulator activity; GO:0043167 ion binding; GO:0005515 protein binding; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0008201 heparin binding; GO:0008270 zinc ion binding; GO:0004866 endopeptidase inhibitor activity; GO:1901681 sulfur compound binding; GO:0004869 cysteine-type endopeptidase inhibitor activity; GO:0097367 carbohydrate derivative binding; GO:0046914 transition metal ion binding; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0030414 peptidase inhibitor activity; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0061135 endopeptidase regulator activity; GO:0043168 anion binding; GO:0005539 glycosaminoglycan binding; ","K03898","KNG; kininogen","hsa04610 Complement and coagulation cascades - Homo sapiens (human); ","IPR000010; IPR027358; ","Cystatin domain; Kininogen-type cystatin domain; \r"]
["P01111","GTPase NRas OS=Homo sapiens OX=9606 GN=NRAS","NRAS",21.229,7.0256,18,3,5,3,1.053,1.039,0.943,1.03,0.897,1.057,0.983,0.781,"cytoplasm\r","GO:0044700 single organism signaling; GO:0045321 leukocyte activation; GO:0002220 innate immune response activating cell surface receptor signaling pathway; GO:0007166 cell surface receptor signaling pathway; GO:0032989 cellular component morphogenesis; GO:0031347 regulation of defense response; GO:0044237 cellular metabolic process; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0038127 ERBB signaling pathway; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0033365 protein localization to organelle; GO:0008104 protein localization; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0002758 innate immune response-activating signal transduction; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0048812 neuron projection morphogenesis; GO:0048870 cell motility; GO:0007264 small GTPase mediated signal transduction; GO:0006935 chemotaxis; GO:0032501 multicellular organismal process; GO:0050776 regulation of immune response; GO:0000902 cell morphogenesis; GO:0006810 transport; GO:0000165 MAPK cascade; GO:0050900 leukocyte migration; GO:0002223 stimulatory C-type lectin receptor signaling pathway; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0002682 regulation of immune system process; GO:0006464 cellular protein modification process; GO:0042330 taxis; GO:0050794 regulation of cellular process; GO:0016310 phosphorylation; GO:0044707 single-multicellular organism process; GO:0002283 neutrophil activation involved in immune response; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0044267 cellular protein metabolic process; GO:0080134 regulation of response to stress; GO:0007173 epidermal growth factor receptor signaling pathway; GO:0009653 anatomical structure morphogenesis; GO:0031349 positive regulation of defense response; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0007409 axonogenesis; GO:0007275 multicellular organism development; GO:0038093 Fc receptor signaling pathway; GO:0034613 cellular protein localization; GO:0050778 positive regulation of immune response; GO:0023014 signal transduction by protein phosphorylation; GO:0002253 activation of immune response; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:0002263 cell activation involved in immune response; GO:0045184 establishment of protein localization; GO:0030182 neuron differentiation; GO:0045055 regulated exocytosis; GO:0006793 phosphorus metabolic process; GO:0097485 neuron projection guidance; GO:0006928 movement of cell or subcellular component; GO:0001775 cell activation; GO:0048584 positive regulation of response to stimulus; GO:0043412 macromolecule modification; GO:0051179 localization; GO:0006955 immune response; GO:0006887 exocytosis; GO:0072594 establishment of protein localization to organelle; GO:0051674 localization of cell; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0032990 cell part morphogenesis; GO:0045088 regulation of innate immune response; GO:0048858 cell projection morphogenesis; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0033036 macromolecule localization; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:0002446 neutrophil mediated immunity; GO:0023052 signaling; GO:0002764 immune response-regulating signaling pathway; GO:0002444 myeloid leukocyte mediated immunity; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0030030 cell projection organization; GO:0032940 secretion by cell; GO:0043299 leukocyte degranulation; GO:0040011 locomotion; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0007265 Ras protein signal transduction; GO:0016043 cellular component organization; GO:0016477 cell migration; GO:0002218 activation of innate immune response; GO:0002252 immune effector process; GO:0050896 response to stimulus; GO:0007411 axon guidance; GO:0048468 cell development; GO:0000904 cell morphogenesis involved in differentiation; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0006468 protein phosphorylation; GO:0002757 immune response-activating signal transduction; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0034067 protein localization to Golgi apparatus; GO:0045089 positive regulation of innate immune response; GO:0035556 intracellular signal transduction; GO:0072600 establishment of protein localization to Golgi; GO:0043312 neutrophil degranulation; GO:0031175 neuron projection development; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0002366 leukocyte activation involved in immune response; GO:0061564 axon development; GO:0042119 neutrophil activation; GO:0070727 cellular macromolecule localization; GO:0038128 ERBB2 signaling pathway; GO:0044767 single-organism developmental process; GO:0002684 positive regulation of immune system process; GO:0038095 Fc-epsilon receptor signaling pathway; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070821 tertiary granule membrane; GO:0070062 extracellular exosome; GO:0044464 cell part; GO:0005622 intracellular; GO:0098805 whole membrane; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0070820 tertiary granule; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0030667 secretory granule membrane; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0044877 macromolecular complex binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0032403 protein complex binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0036094 small molecule binding; ","K07828","NRAS; GTPase NRas","hsa04662 B cell receptor signaling pathway - Homo sapiens (human); hsa05220 Chronic myeloid leukemia - Homo sapiens (human); hsa04014 Ras signaling pathway - Homo sapiens (human); hsa04150 mTOR signaling pathway - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa05206 MicroRNAs in cancer - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa04933 AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human); hsa04211 Longevity regulating pathway - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa04917 Prolactin signaling pathway - Homo sapiens (human); hsa05161 Hepatitis B - Homo sapiens (human); hsa05215 Prostate cancer - Homo sapiens (human); hsa01521 EGFR tyrosine kinase inhibitor resistance - Homo sapiens (human); hsa04725 Cholinergic synapse - Homo sapiens (human); hsa04921 Oxytocin signaling pathway - Homo sapiens (human); hsa04218 Cellular senescence - Homo sapiens (human); hsa04722 Neurotrophin signaling pathway - Homo sapiens (human); hsa04371 Apelin signaling pathway - Homo sapiens (human); hsa05160 Hepatitis C - Homo sapiens (human); hsa04916 Melanogenesis - Homo sapiens (human); hsa05167 Kaposi's sarcoma-associated herpesvirus infection - Homo sapiens (human); hsa04010 MAPK signaling pathway - Homo sapiens (human); hsa05219 Bladder cancer - Homo sapiens (human); hsa04664 Fc epsilon RI signaling pathway - Homo sapiens (human); hsa04540 Gap junction - Homo sapiens (human); hsa04912 GnRH signaling pathway - Homo sapiens (human); hsa05203 Viral carcinogenesis - Homo sapiens (human); hsa04730 Long-term depression - Homo sapiens (human); hsa05226 Gastric cancer - Homo sapiens (human); hsa04720 Long-term potentiation - Homo sapiens (human); hsa05218 Melanoma - Homo sapiens (human); hsa04550 Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human); hsa04015 Rap1 signaling pathway - Homo sapiens (human); hsa04072 Phospholipase D signaling pathway - Homo sapiens (human); hsa04650 Natural killer cell mediated cytotoxicity - Homo sapiens (human); hsa04625 C-type lectin receptor signaling pathway - Homo sapiens (human); hsa05221 Acute myeloid leukemia - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa05230 Central carbon metabolism in cancer - Homo sapiens (human); hsa05166 HTLV-I infection - Homo sapiens (human); hsa04140 Autophagy - animal - Homo sapiens (human); hsa04071 Sphingolipid signaling pathway - Homo sapiens (human); hsa05213 Endometrial cancer - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa05224 Breast cancer - Homo sapiens (human); hsa01522 Endocrine resistance - Homo sapiens (human); hsa05034 Alcoholism - Homo sapiens (human); hsa05210 Colorectal cancer - Homo sapiens (human); hsa04915 Estrogen signaling pathway - Homo sapiens (human); hsa05216 Thyroid cancer - Homo sapiens (human); hsa05231 Choline metabolism in cancer - Homo sapiens (human); hsa04210 Apoptosis - Homo sapiens (human); hsa04370 VEGF signaling pathway - Homo sapiens (human); hsa04137 Mitophagy - animal - Homo sapiens (human); hsa04910 Insulin signaling pathway - Homo sapiens (human); hsa05211 Renal cell carcinoma - Homo sapiens (human); hsa05225 Hepatocellular carcinoma - Homo sapiens (human); hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa04660 T cell receptor signaling pathway - Homo sapiens (human); hsa04726 Serotonergic synapse - Homo sapiens (human); hsa04213 Longevity regulating pathway - multiple species - Homo sapiens (human); hsa04062 Chemokine signaling pathway - Homo sapiens (human); hsa05223 Non-small cell lung cancer - Homo sapiens (human); hsa04068 FoxO signaling pathway - Homo sapiens (human); hsa05214 Glioma - Homo sapiens (human); hsa04012 ErbB signaling pathway - Homo sapiens (human); hsa04360 Axon guidance - Homo sapiens (human); hsa04926 Relaxin signaling pathway - Homo sapiens (human); ","IPR005225; IPR027417; ","Small GTP-binding protein domain; P-loop containing nucleoside triphosphate hydrolase; \r"]
["P01591","Immunoglobulin J chain OS=Homo sapiens OX=9606 GN=JCHAIN","JCHAIN",18.098,9.89,20.8,3,6,3,1.022,1.095,1.013,1.032,0.841,0.959,0.905,0.187,"extracellular\r","GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0016477 cell migration; GO:0065008 regulation of biological quality; GO:0051674 localization of cell; GO:0098542 defense response to other organism; GO:0044699 single-organism process; GO:0060263 regulation of respiratory burst; GO:0006959 humoral immune response; GO:0044087 regulation of cellular component biogenesis; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0032459 regulation of protein oligomerization; GO:0048871 multicellular organismal homeostasis; GO:0060249 anatomical structure homeostasis; GO:0045087 innate immune response; GO:0009607 response to biotic stimulus; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0009605 response to external stimulus; GO:0042592 homeostatic process; GO:0060267 positive regulation of respiratory burst; GO:0009893 positive regulation of metabolic process; GO:0002250 adaptive immune response; GO:0032461 positive regulation of protein oligomerization; GO:0031334 positive regulation of protein complex assembly; GO:0006898 receptor-mediated endocytosis; GO:0009987 cellular process; GO:0009617 response to bacterium; GO:0019731 antibacterial humoral response; GO:0003094 glomerular filtration; GO:0003008 system process; GO:0006950 response to stress; GO:0042742 defense response to bacterium; GO:0019730 antimicrobial humoral response; GO:0016192 vesicle-mediated transport; GO:0003014 renal system process; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0002376 immune system process; GO:0048870 cell motility; GO:0006897 endocytosis; GO:0032501 multicellular organismal process; GO:0048518 positive regulation of biological process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0043254 regulation of protein complex assembly; GO:0050789 regulation of biological process; GO:0050900 leukocyte migration; GO:0001895 retina homeostasis; GO:0001894 tissue homeostasis; GO:0019222 regulation of metabolic process; GO:0006928 movement of cell or subcellular component; GO:0051128 regulation of cellular component organization; GO:0006952 defense response; GO:0040011 locomotion; GO:0006955 immune response; GO:0051179 localization; GO:0044089 positive regulation of cellular component biogenesis; GO:0097205 renal filtration; GO:0065007 biological regulation; ","GO:0071756 pentameric IgM immunoglobulin complex; GO:0044421 extracellular region part; GO:0005615 extracellular space; GO:0042571 immunoglobulin complex, circulating; GO:0031982 vesicle; GO:0019814 immunoglobulin complex; GO:0032991 macromolecular complex; GO:0071746 IgA immunoglobulin complex, circulating; GO:0071745 IgA immunoglobulin complex; GO:0005576 extracellular region; GO:0071754 IgM immunoglobulin complex, circulating; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0071750 dimeric IgA immunoglobulin complex; GO:0072562 blood microparticle; GO:0071749 polymeric IgA immunoglobulin complex; GO:0071751 secretory IgA immunoglobulin complex; GO:0071752 secretory dimeric IgA immunoglobulin complex; GO:1903561 extracellular vesicle; GO:0071753 IgM immunoglobulin complex; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0071748 monomeric IgA immunoglobulin complex; GO:0043230 extracellular organelle; ","GO:0042802 identical protein binding; GO:0030674 protein binding, bridging; GO:0019862 IgA binding; GO:0019865 immunoglobulin binding; GO:0005102 receptor binding; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0046983 protein dimerization activity; GO:0044877 macromolecular complex binding; GO:0034987 immunoglobulin receptor binding; GO:0060090 binding, bridging; GO:0005515 protein binding; GO:0003823 antigen binding; GO:0032403 protein complex binding; "]
["P01594","Immunoglobulin kappa variable 1-33 OS=Homo sapiens OX=9606 GN=IGKV1-33","IGKV1-33",12.848,32.368,13.7,1,2,1,0.842,0.94,0.86,1.079,1.181,1.091,1.268,0.00572,"extracellular\r","GO:0044700 single organism signaling; GO:0016064 immunoglobulin mediated immune response; GO:0051674 localization of cell; GO:0007166 cell surface receptor signaling pathway; GO:0038094 Fc-gamma receptor signaling pathway; GO:0044699 single-organism process; GO:0006909 phagocytosis; GO:0051234 establishment of localization; GO:0006956 complement activation; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0007154 cell communication; GO:0002250 adaptive immune response; GO:0006958 complement activation, classical pathway; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0044765 single-organism transport; GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0044763 single-organism cellular process; GO:0048870 cell motility; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0050900 leukocyte migration; GO:0048583 regulation of response to stimulus; GO:0002682 regulation of immune system process; GO:0002431 Fc receptor mediated stimulatory signaling pathway; GO:0040011 locomotion; GO:0050794 regulation of cellular process; GO:0016477 cell migration; GO:0002252 immune effector process; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0006959 humoral immune response; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0019724 B cell mediated immunity; GO:1902578 single-organism localization; GO:0002757 immune response-activating signal transduction; GO:0006508 proteolysis; GO:0006898 receptor-mediated endocytosis; GO:0002449 lymphocyte mediated immunity; GO:0038093 Fc receptor signaling pathway; GO:0050778 positive regulation of immune response; GO:0009987 cellular process; GO:0002253 activation of immune response; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0072376 protein activation cascade; GO:0044238 primary metabolic process; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0002684 positive regulation of immune system process; GO:0038095 Fc-epsilon receptor signaling pathway; GO:0006928 movement of cell or subcellular component; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis; GO:0051179 localization; GO:0006955 immune response; GO:0048584 positive regulation of response to stimulus; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0072562 blood microparticle; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0004252 serine-type endopeptidase activity; GO:0004175 endopeptidase activity; GO:0008233 peptidase activity; GO:0003824 catalytic activity; GO:0017171 serine hydrolase activity; GO:0005488 binding; GO:0008236 serine-type peptidase activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0003823 antigen binding; ",{"$nulls":3},"IPR007110; IPR013783; IPR003599; IPR013106; ","Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin subtype; Immunoglobulin V-set domain; \r"]
["P01701","Immunoglobulin lambda variable 1-51 OS=Homo sapiens OX=9606 GN=IGLV1-51","IGLV1-51",12.249,4.0002,13.7,2,5,2,1.066,0.901,1.077,0.945,1.01,0.99,0.967,0.647,"extracellular\r","GO:0044700 single organism signaling; GO:0016064 immunoglobulin mediated immune response; GO:0051674 localization of cell; GO:0007166 cell surface receptor signaling pathway; GO:0038094 Fc-gamma receptor signaling pathway; GO:0044699 single-organism process; GO:0006909 phagocytosis; GO:0051234 establishment of localization; GO:0006956 complement activation; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0007154 cell communication; GO:0002250 adaptive immune response; GO:0006958 complement activation, classical pathway; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0044765 single-organism transport; GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0044763 single-organism cellular process; GO:0048870 cell motility; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0050900 leukocyte migration; GO:0048583 regulation of response to stimulus; GO:0002682 regulation of immune system process; GO:0002431 Fc receptor mediated stimulatory signaling pathway; GO:0040011 locomotion; GO:0050794 regulation of cellular process; GO:0016477 cell migration; GO:0002252 immune effector process; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0006959 humoral immune response; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0019724 B cell mediated immunity; GO:1902578 single-organism localization; GO:0002757 immune response-activating signal transduction; GO:0006508 proteolysis; GO:0006898 receptor-mediated endocytosis; GO:0002449 lymphocyte mediated immunity; GO:0038093 Fc receptor signaling pathway; GO:0050778 positive regulation of immune response; GO:0009987 cellular process; GO:0002253 activation of immune response; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0072376 protein activation cascade; GO:0044238 primary metabolic process; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0002684 positive regulation of immune system process; GO:0038095 Fc-epsilon receptor signaling pathway; GO:0006928 movement of cell or subcellular component; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis; GO:0051179 localization; GO:0006955 immune response; GO:0048584 positive regulation of response to stimulus; GO:0065007 biological regulation; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0071944 cell periphery; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0005576 extracellular region; GO:0043230 extracellular organelle; GO:0005886 plasma membrane; ","GO:0004252 serine-type endopeptidase activity; GO:0004175 endopeptidase activity; GO:0008233 peptidase activity; GO:0003824 catalytic activity; GO:0017171 serine hydrolase activity; GO:0005488 binding; GO:0008236 serine-type peptidase activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0003823 antigen binding; ",{"$nulls":3},"IPR007110; IPR013783; IPR003599; IPR013106; ","Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin subtype; Immunoglobulin V-set domain; \r"]
["P01714","Immunoglobulin lambda variable 3-19 OS=Homo sapiens OX=9606 GN=IGLV3-19","IGLV3-19",12.042,4.6119,17,2,2,2,1.083,1.24,1.306,0.785,0.898,0.719,0.662,0.00836,"extracellular\r","GO:0044700 single organism signaling; GO:0016064 immunoglobulin mediated immune response; GO:0051674 localization of cell; GO:0007166 cell surface receptor signaling pathway; GO:0038094 Fc-gamma receptor signaling pathway; GO:0044699 single-organism process; GO:0006909 phagocytosis; GO:0051234 establishment of localization; GO:0006956 complement activation; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0007154 cell communication; GO:0002250 adaptive immune response; GO:0006958 complement activation, classical pathway; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0044765 single-organism transport; GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0044763 single-organism cellular process; GO:0048870 cell motility; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0050900 leukocyte migration; GO:0048583 regulation of response to stimulus; GO:0002682 regulation of immune system process; GO:0002431 Fc receptor mediated stimulatory signaling pathway; GO:0040011 locomotion; GO:0050794 regulation of cellular process; GO:0016477 cell migration; GO:0002252 immune effector process; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0006959 humoral immune response; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0019724 B cell mediated immunity; GO:1902578 single-organism localization; GO:0002757 immune response-activating signal transduction; GO:0006508 proteolysis; GO:0006898 receptor-mediated endocytosis; GO:0002449 lymphocyte mediated immunity; GO:0038093 Fc receptor signaling pathway; GO:0050778 positive regulation of immune response; GO:0009987 cellular process; GO:0002253 activation of immune response; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0072376 protein activation cascade; GO:0044238 primary metabolic process; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0002684 positive regulation of immune system process; GO:0038095 Fc-epsilon receptor signaling pathway; GO:0006928 movement of cell or subcellular component; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis; GO:0051179 localization; GO:0006955 immune response; GO:0048584 positive regulation of response to stimulus; GO:0065007 biological regulation; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0071944 cell periphery; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0005576 extracellular region; GO:0043230 extracellular organelle; GO:0005886 plasma membrane; ","GO:0004252 serine-type endopeptidase activity; GO:0004175 endopeptidase activity; GO:0008233 peptidase activity; GO:0003824 catalytic activity; GO:0017171 serine hydrolase activity; GO:0005488 binding; GO:0008236 serine-type peptidase activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0003823 antigen binding; ",{"$nulls":3},"IPR007110; IPR013783; IPR003599; IPR013106; ","Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin subtype; Immunoglobulin V-set domain; \r"]
["P01742","Immunoglobulin heavy variable 1-69 OS=Homo sapiens OX=9606 GN=IGHV1-69","IGHV1-69",12.659,10.192,26.5,3,7,2,0.823,0.893,0.852,1.088,1.155,1.177,1.332,0.00102,"extracellular\r","GO:0044700 single organism signaling; GO:0016064 immunoglobulin mediated immune response; GO:0051674 localization of cell; GO:0007166 cell surface receptor signaling pathway; GO:0038094 Fc-gamma receptor signaling pathway; GO:0044699 single-organism process; GO:0006909 phagocytosis; GO:0051234 establishment of localization; GO:0006956 complement activation; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0007154 cell communication; GO:0002250 adaptive immune response; GO:0006958 complement activation, classical pathway; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0044765 single-organism transport; GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0044763 single-organism cellular process; GO:0048870 cell motility; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0050900 leukocyte migration; GO:0048583 regulation of response to stimulus; GO:0002682 regulation of immune system process; GO:0002431 Fc receptor mediated stimulatory signaling pathway; GO:0040011 locomotion; GO:0050794 regulation of cellular process; GO:0016477 cell migration; GO:0002252 immune effector process; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0006959 humoral immune response; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0019724 B cell mediated immunity; GO:1902578 single-organism localization; GO:0002757 immune response-activating signal transduction; GO:0006508 proteolysis; GO:0006898 receptor-mediated endocytosis; GO:0002449 lymphocyte mediated immunity; GO:0038093 Fc receptor signaling pathway; GO:0050778 positive regulation of immune response; GO:0009987 cellular process; GO:0002253 activation of immune response; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0072376 protein activation cascade; GO:0044238 primary metabolic process; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0002684 positive regulation of immune system process; GO:0038095 Fc-epsilon receptor signaling pathway; GO:0006928 movement of cell or subcellular component; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis; GO:0051179 localization; GO:0006955 immune response; GO:0048584 positive regulation of response to stimulus; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005623 cell; GO:0044464 cell part; GO:0071944 cell periphery; GO:0005576 extracellular region; GO:0005886 plasma membrane; ","GO:0004252 serine-type endopeptidase activity; GO:0004175 endopeptidase activity; GO:0008233 peptidase activity; GO:0003824 catalytic activity; GO:0017171 serine hydrolase activity; GO:0005488 binding; GO:0008236 serine-type peptidase activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0003823 antigen binding; ",{"$nulls":3},"IPR007110; IPR013783; IPR013106; ","Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin V-set domain; \r"]
["P01780","Immunoglobulin heavy variable 3-7 OS=Homo sapiens OX=9606 GN=IGHV3-7","IGHV3-7",12.943,5.5289,23.1,3,9,2,0.987,0.933,0.938,1.047,1.06,1.067,1.111,0.00498,"extracellular\r","GO:0044700 single organism signaling; GO:0016064 immunoglobulin mediated immune response; GO:0051674 localization of cell; GO:0007166 cell surface receptor signaling pathway; GO:0038094 Fc-gamma receptor signaling pathway; GO:0044699 single-organism process; GO:0006909 phagocytosis; GO:0051234 establishment of localization; GO:0006956 complement activation; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0007154 cell communication; GO:0002250 adaptive immune response; GO:0006958 complement activation, classical pathway; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0044765 single-organism transport; GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0044763 single-organism cellular process; GO:0048870 cell motility; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0050900 leukocyte migration; GO:0048583 regulation of response to stimulus; GO:0002682 regulation of immune system process; GO:0002431 Fc receptor mediated stimulatory signaling pathway; GO:0040011 locomotion; GO:0050794 regulation of cellular process; GO:0016477 cell migration; GO:0002252 immune effector process; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0006959 humoral immune response; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0019724 B cell mediated immunity; GO:1902578 single-organism localization; GO:0002757 immune response-activating signal transduction; GO:0006508 proteolysis; GO:0006898 receptor-mediated endocytosis; GO:0002449 lymphocyte mediated immunity; GO:0038093 Fc receptor signaling pathway; GO:0050778 positive regulation of immune response; GO:0009987 cellular process; GO:0002253 activation of immune response; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0072376 protein activation cascade; GO:0044238 primary metabolic process; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0002684 positive regulation of immune system process; GO:0038095 Fc-epsilon receptor signaling pathway; GO:0006928 movement of cell or subcellular component; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis; GO:0051179 localization; GO:0006955 immune response; GO:0048584 positive regulation of response to stimulus; GO:0065007 biological regulation; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0071944 cell periphery; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0005576 extracellular region; GO:0043230 extracellular organelle; GO:0005886 plasma membrane; ","GO:0004252 serine-type endopeptidase activity; GO:0004175 endopeptidase activity; GO:0008233 peptidase activity; GO:0003824 catalytic activity; GO:0017171 serine hydrolase activity; GO:0005488 binding; GO:0008236 serine-type peptidase activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0003823 antigen binding; ",{"$nulls":3},"IPR007110; IPR013783; IPR013106; ","Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin V-set domain; \r"]
["P01834","Immunoglobulin kappa constant OS=Homo sapiens OX=9606 GN=IGKC","IGKC",11.765,53.384,80.4,6,75,2,1,0.983,0.989,1.06,1.048,0.983,1.04,0.182,"extracellular\r","GO:0044700 single organism signaling; GO:0002694 regulation of leukocyte activation; GO:0016064 immunoglobulin mediated immune response; GO:0065008 regulation of biological quality; GO:0051674 localization of cell; GO:0007166 cell surface receptor signaling pathway; GO:0038094 Fc-gamma receptor signaling pathway; GO:0098542 defense response to other organism; GO:0044699 single-organism process; GO:0051249 regulation of lymphocyte activation; GO:0048871 multicellular organismal homeostasis; GO:0009607 response to biotic stimulus; GO:0051234 establishment of localization; GO:0006909 phagocytosis; GO:0006956 complement activation; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0002250 adaptive immune response; GO:0006958 complement activation, classical pathway; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0050851 antigen receptor-mediated signaling pathway; GO:0044765 single-organism transport; GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis; GO:0051716 cellular response to stimulus; GO:0006911 phagocytosis, engulfment; GO:0002443 leukocyte mediated immunity; GO:0006910 phagocytosis, recognition; GO:0050864 regulation of B cell activation; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0051251 positive regulation of lymphocyte activation; GO:0048870 cell motility; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0050853 B cell receptor signaling pathway; GO:0006810 transport; GO:0050865 regulation of cell activation; GO:0050900 leukocyte migration; GO:0050789 regulation of biological process; GO:0001895 retina homeostasis; GO:0001894 tissue homeostasis; GO:0048583 regulation of response to stimulus; GO:0002682 regulation of immune system process; GO:0002431 Fc receptor mediated stimulatory signaling pathway; GO:0040011 locomotion; GO:0006952 defense response; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0016477 cell migration; GO:0016043 cellular component organization; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0002252 immune effector process; GO:0010324 membrane invagination; GO:0006959 humoral immune response; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0008037 cell recognition; GO:0051707 response to other organism; GO:0060249 anatomical structure homeostasis; GO:0045087 innate immune response; GO:0019724 B cell mediated immunity; GO:0071704 organic substance metabolic process; GO:0099024 plasma membrane invagination; GO:0042592 homeostatic process; GO:0050867 positive regulation of cell activation; GO:1902578 single-organism localization; GO:0050871 positive regulation of B cell activation; GO:0002757 immune response-activating signal transduction; GO:0006508 proteolysis; GO:0006898 receptor-mediated endocytosis; GO:0038093 Fc receptor signaling pathway; GO:0002449 lymphocyte mediated immunity; GO:0009987 cellular process; GO:0050778 positive regulation of immune response; GO:0009617 response to bacterium; GO:0002253 activation of immune response; GO:0006950 response to stress; GO:0042742 defense response to bacterium; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0072376 protein activation cascade; GO:0006897 endocytosis; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0002696 positive regulation of leukocyte activation; GO:0061024 membrane organization; GO:0002684 positive regulation of immune system process; GO:0038095 Fc-epsilon receptor signaling pathway; GO:0006928 movement of cell or subcellular component; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis; GO:0006955 immune response; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0009897 external side of plasma membrane; GO:0071944 cell periphery; GO:0042571 immunoglobulin complex, circulating; GO:0031982 vesicle; GO:0019814 immunoglobulin complex; GO:0032991 macromolecular complex; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0072562 blood microparticle; GO:0044459 plasma membrane part; GO:0044464 cell part; GO:0044425 membrane part; GO:1903561 extracellular vesicle; GO:0009986 cell surface; GO:0043227 membrane-bounded organelle; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0098552 side of membrane; ","GO:0004252 serine-type endopeptidase activity; GO:0004175 endopeptidase activity; GO:0008233 peptidase activity; GO:0005102 receptor binding; GO:0003824 catalytic activity; GO:0017171 serine hydrolase activity; GO:0005488 binding; GO:0008236 serine-type peptidase activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0034987 immunoglobulin receptor binding; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0003823 antigen binding; ",{"$nulls":3},"IPR007110; IPR013783; IPR003597; ","Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin C1-set; \r"]
["P01859","Immunoglobulin heavy constant gamma 2 OS=Homo sapiens OX=9606 GN=IGHG2","IGHG2",35.9,146.81,48.8,13,89,6,1.017,0.997,0.986,1,0.989,0.994,0.994,0.59,"mitochondria\r","GO:0044700 single organism signaling; GO:0002694 regulation of leukocyte activation; GO:0016064 immunoglobulin mediated immune response; GO:0007166 cell surface receptor signaling pathway; GO:0038094 Fc-gamma receptor signaling pathway; GO:0098542 defense response to other organism; GO:0044699 single-organism process; GO:0051249 regulation of lymphocyte activation; GO:0009607 response to biotic stimulus; GO:0051234 establishment of localization; GO:0006909 phagocytosis; GO:0006956 complement activation; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0002250 adaptive immune response; GO:0006958 complement activation, classical pathway; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0050851 antigen receptor-mediated signaling pathway; GO:0044765 single-organism transport; GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis; GO:0051716 cellular response to stimulus; GO:0006911 phagocytosis, engulfment; GO:0002443 leukocyte mediated immunity; GO:0006910 phagocytosis, recognition; GO:0050864 regulation of B cell activation; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0051251 positive regulation of lymphocyte activation; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0050853 B cell receptor signaling pathway; GO:0006810 transport; GO:0050865 regulation of cell activation; GO:0050789 regulation of biological process; GO:0048583 regulation of response to stimulus; GO:0002682 regulation of immune system process; GO:0002431 Fc receptor mediated stimulatory signaling pathway; GO:0006952 defense response; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0002252 immune effector process; GO:0010324 membrane invagination; GO:0006959 humoral immune response; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0008037 cell recognition; GO:0051707 response to other organism; GO:0045087 innate immune response; GO:0019724 B cell mediated immunity; GO:0071704 organic substance metabolic process; GO:0099024 plasma membrane invagination; GO:0050867 positive regulation of cell activation; GO:1902578 single-organism localization; GO:0050871 positive regulation of B cell activation; GO:0002757 immune response-activating signal transduction; GO:0006508 proteolysis; GO:0038093 Fc receptor signaling pathway; GO:0002449 lymphocyte mediated immunity; GO:0009987 cellular process; GO:0050778 positive regulation of immune response; GO:0009617 response to bacterium; GO:0002253 activation of immune response; GO:0006950 response to stress; GO:0042742 defense response to bacterium; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0072376 protein activation cascade; GO:0006897 endocytosis; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0002696 positive regulation of leukocyte activation; GO:0061024 membrane organization; GO:0002684 positive regulation of immune system process; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis; GO:0006955 immune response; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0009897 external side of plasma membrane; GO:0071944 cell periphery; GO:0042571 immunoglobulin complex, circulating; GO:0031982 vesicle; GO:0019814 immunoglobulin complex; GO:0032991 macromolecular complex; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0072562 blood microparticle; GO:0044459 plasma membrane part; GO:0044464 cell part; GO:0044425 membrane part; GO:1903561 extracellular vesicle; GO:0009986 cell surface; GO:0043227 membrane-bounded organelle; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0098552 side of membrane; ","GO:0004252 serine-type endopeptidase activity; GO:0004175 endopeptidase activity; GO:0008233 peptidase activity; GO:0005102 receptor binding; GO:0003824 catalytic activity; GO:0017171 serine hydrolase activity; GO:0005488 binding; GO:0008236 serine-type peptidase activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0034987 immunoglobulin receptor binding; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0003823 antigen binding; ",{"$nulls":3},"IPR007110; IPR013783; IPR003597; ","Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin C1-set; \r"]
["P01860","Immunoglobulin heavy constant gamma 3 OS=Homo sapiens OX=9606 GN=IGHG3","IGHG3",41.287,159.92,46.9,13,95,5,0.833,0.822,0.832,1.203,1.155,1.145,1.409,2.35e-05,"extracellular\r","GO:0044700 single organism signaling; GO:0002694 regulation of leukocyte activation; GO:0016064 immunoglobulin mediated immune response; GO:0065008 regulation of biological quality; GO:0007166 cell surface receptor signaling pathway; GO:0038094 Fc-gamma receptor signaling pathway; GO:0098542 defense response to other organism; GO:0044699 single-organism process; GO:0051249 regulation of lymphocyte activation; GO:0048871 multicellular organismal homeostasis; GO:0009607 response to biotic stimulus; GO:0051234 establishment of localization; GO:0006909 phagocytosis; GO:0006956 complement activation; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0002250 adaptive immune response; GO:0006958 complement activation, classical pathway; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0050851 antigen receptor-mediated signaling pathway; GO:0044765 single-organism transport; GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis; GO:0051716 cellular response to stimulus; GO:0006911 phagocytosis, engulfment; GO:0002443 leukocyte mediated immunity; GO:0006910 phagocytosis, recognition; GO:0050864 regulation of B cell activation; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0051251 positive regulation of lymphocyte activation; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0050853 B cell receptor signaling pathway; GO:0006810 transport; GO:0050865 regulation of cell activation; GO:0050789 regulation of biological process; GO:0001895 retina homeostasis; GO:0001894 tissue homeostasis; GO:0048583 regulation of response to stimulus; GO:0002682 regulation of immune system process; GO:0002431 Fc receptor mediated stimulatory signaling pathway; GO:0006952 defense response; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0002252 immune effector process; GO:0010324 membrane invagination; GO:0006959 humoral immune response; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0008037 cell recognition; GO:0051707 response to other organism; GO:0060249 anatomical structure homeostasis; GO:0045087 innate immune response; GO:0019724 B cell mediated immunity; GO:0071704 organic substance metabolic process; GO:0099024 plasma membrane invagination; GO:0042592 homeostatic process; GO:0050867 positive regulation of cell activation; GO:1902578 single-organism localization; GO:0050871 positive regulation of B cell activation; GO:0002757 immune response-activating signal transduction; GO:0006508 proteolysis; GO:0038093 Fc receptor signaling pathway; GO:0002449 lymphocyte mediated immunity; GO:0009987 cellular process; GO:0050778 positive regulation of immune response; GO:0009617 response to bacterium; GO:0002253 activation of immune response; GO:0006950 response to stress; GO:0042742 defense response to bacterium; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0072376 protein activation cascade; GO:0006897 endocytosis; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0002696 positive regulation of leukocyte activation; GO:0061024 membrane organization; GO:0002684 positive regulation of immune system process; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis; GO:0006955 immune response; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0009897 external side of plasma membrane; GO:0071944 cell periphery; GO:0042571 immunoglobulin complex, circulating; GO:0031982 vesicle; GO:0019814 immunoglobulin complex; GO:0032991 macromolecular complex; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0072562 blood microparticle; GO:0044459 plasma membrane part; GO:0044464 cell part; GO:0044425 membrane part; GO:1903561 extracellular vesicle; GO:0009986 cell surface; GO:0043227 membrane-bounded organelle; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0098552 side of membrane; ","GO:0004252 serine-type endopeptidase activity; GO:0004175 endopeptidase activity; GO:0008233 peptidase activity; GO:0005102 receptor binding; GO:0003824 catalytic activity; GO:0017171 serine hydrolase activity; GO:0005488 binding; GO:0008236 serine-type peptidase activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0034987 immunoglobulin receptor binding; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0003823 antigen binding; ",{"$nulls":3},"IPR007110; IPR013783; IPR003597; ","Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin C1-set; \r"]
["P01861","Immunoglobulin heavy constant gamma 4 OS=Homo sapiens OX=9606 GN=IGHG4","IGHG4",35.94,72.601,49.8,11,60,5,0.801,0.824,0.806,1.176,1.16,1.191,1.451,2.7E-6,"mitochondria\r","GO:0044700 single organism signaling; GO:0002694 regulation of leukocyte activation; GO:0016064 immunoglobulin mediated immune response; GO:0007166 cell surface receptor signaling pathway; GO:0038094 Fc-gamma receptor signaling pathway; GO:0098542 defense response to other organism; GO:0044699 single-organism process; GO:0051249 regulation of lymphocyte activation; GO:0009607 response to biotic stimulus; GO:0051234 establishment of localization; GO:0006909 phagocytosis; GO:0006956 complement activation; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0002250 adaptive immune response; GO:0006958 complement activation, classical pathway; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0050851 antigen receptor-mediated signaling pathway; GO:0044765 single-organism transport; GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis; GO:0051716 cellular response to stimulus; GO:0006911 phagocytosis, engulfment; GO:0002443 leukocyte mediated immunity; GO:0006910 phagocytosis, recognition; GO:0050864 regulation of B cell activation; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0051251 positive regulation of lymphocyte activation; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0050853 B cell receptor signaling pathway; GO:0006810 transport; GO:0050865 regulation of cell activation; GO:0050789 regulation of biological process; GO:0048583 regulation of response to stimulus; GO:0002682 regulation of immune system process; GO:0002431 Fc receptor mediated stimulatory signaling pathway; GO:0006952 defense response; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0002252 immune effector process; GO:0010324 membrane invagination; GO:0006959 humoral immune response; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0008037 cell recognition; GO:0051707 response to other organism; GO:0045087 innate immune response; GO:0019724 B cell mediated immunity; GO:0071704 organic substance metabolic process; GO:0099024 plasma membrane invagination; GO:0050867 positive regulation of cell activation; GO:1902578 single-organism localization; GO:0050871 positive regulation of B cell activation; GO:0002757 immune response-activating signal transduction; GO:0006508 proteolysis; GO:0038093 Fc receptor signaling pathway; GO:0002449 lymphocyte mediated immunity; GO:0009987 cellular process; GO:0050778 positive regulation of immune response; GO:0009617 response to bacterium; GO:0002253 activation of immune response; GO:0006950 response to stress; GO:0042742 defense response to bacterium; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0072376 protein activation cascade; GO:0006897 endocytosis; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0002696 positive regulation of leukocyte activation; GO:0061024 membrane organization; GO:0002684 positive regulation of immune system process; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis; GO:0006955 immune response; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0009897 external side of plasma membrane; GO:0071944 cell periphery; GO:0042571 immunoglobulin complex, circulating; GO:0031982 vesicle; GO:0019814 immunoglobulin complex; GO:0032991 macromolecular complex; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0072562 blood microparticle; GO:0044459 plasma membrane part; GO:0044464 cell part; GO:0044425 membrane part; GO:1903561 extracellular vesicle; GO:0009986 cell surface; GO:0043227 membrane-bounded organelle; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0098552 side of membrane; ","GO:0004252 serine-type endopeptidase activity; GO:0004175 endopeptidase activity; GO:0008233 peptidase activity; GO:0005102 receptor binding; GO:0003824 catalytic activity; GO:0017171 serine hydrolase activity; GO:0005488 binding; GO:0008236 serine-type peptidase activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0034987 immunoglobulin receptor binding; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0003823 antigen binding; ",{"$nulls":3},"IPR007110; IPR013783; IPR003597; ","Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin C1-set; \r"]
["P01871","Immunoglobulin heavy constant mu OS=Homo sapiens OX=9606 GN=IGHM","IGHM",49.439,239.84,41.1,18,59,7,1.116,1.176,1.075,0.86,0.936,0.908,0.803,0.00366,"nucleus\r","GO:0044700 single organism signaling; GO:0002694 regulation of leukocyte activation; GO:0016064 immunoglobulin mediated immune response; GO:0051674 localization of cell; GO:0007166 cell surface receptor signaling pathway; GO:0098542 defense response to other organism; GO:0044699 single-organism process; GO:0051249 regulation of lymphocyte activation; GO:0009607 response to biotic stimulus; GO:0051234 establishment of localization; GO:0006909 phagocytosis; GO:0006956 complement activation; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0002250 adaptive immune response; GO:0006958 complement activation, classical pathway; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0019731 antibacterial humoral response; GO:0050851 antigen receptor-mediated signaling pathway; GO:0044765 single-organism transport; GO:0051716 cellular response to stimulus; GO:0006911 phagocytosis, engulfment; GO:0002443 leukocyte mediated immunity; GO:0050829 defense response to Gram-negative bacterium; GO:0006910 phagocytosis, recognition; GO:0019730 antimicrobial humoral response; GO:0050864 regulation of B cell activation; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0051251 positive regulation of lymphocyte activation; GO:0048870 cell motility; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0050853 B cell receptor signaling pathway; GO:0006810 transport; GO:0050865 regulation of cell activation; GO:0050900 leukocyte migration; GO:0050789 regulation of biological process; GO:0048583 regulation of response to stimulus; GO:0002682 regulation of immune system process; GO:0040011 locomotion; GO:0006952 defense response; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0016477 cell migration; GO:0002252 immune effector process; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0010324 membrane invagination; GO:0006959 humoral immune response; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0008037 cell recognition; GO:0045087 innate immune response; GO:0071704 organic substance metabolic process; GO:0019724 B cell mediated immunity; GO:0099024 plasma membrane invagination; GO:0050867 positive regulation of cell activation; GO:1902578 single-organism localization; GO:0050871 positive regulation of B cell activation; GO:0002757 immune response-activating signal transduction; GO:0002449 lymphocyte mediated immunity; GO:0009987 cellular process; GO:0050778 positive regulation of immune response; GO:0009617 response to bacterium; GO:0002253 activation of immune response; GO:0006950 response to stress; GO:0042742 defense response to bacterium; GO:0016192 vesicle-mediated transport; GO:0072376 protein activation cascade; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0002696 positive regulation of leukocyte activation; GO:0061024 membrane organization; GO:0002684 positive regulation of immune system process; GO:0006928 movement of cell or subcellular component; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0051179 localization; GO:0006955 immune response; GO:0048584 positive regulation of response to stimulus; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0071756 pentameric IgM immunoglobulin complex; GO:0044421 extracellular region part; GO:0005615 extracellular space; GO:0009897 external side of plasma membrane; GO:0071944 cell periphery; GO:0042571 immunoglobulin complex, circulating; GO:0031982 vesicle; GO:0019814 immunoglobulin complex; GO:0031224 intrinsic component of membrane; GO:0032991 macromolecular complex; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0071754 IgM immunoglobulin complex, circulating; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0072562 blood microparticle; GO:0044459 plasma membrane part; GO:0044425 membrane part; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0009986 cell surface; GO:0071757 hexameric IgM immunoglobulin complex; GO:0071753 IgM immunoglobulin complex; GO:0043227 membrane-bounded organelle; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0098552 side of membrane; ","GO:0005515 protein binding; GO:0003823 antigen binding; GO:0005488 binding; ",{"$nulls":3},"IPR007110; IPR013783; IPR003597; ","Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin C1-set; \r"]
["P01876","Immunoglobulin heavy constant alpha 1 OS=Homo sapiens OX=9606 GN=IGHA1","IGHA1",37.654,275.79,59.8,18,78,10,0.889,0.86,0.92,1.108,1.138,1.086,1.248,0.000722,"extracellular\r","GO:0044700 single organism signaling; GO:0002694 regulation of leukocyte activation; GO:0016064 immunoglobulin mediated immune response; GO:0065008 regulation of biological quality; GO:0051674 localization of cell; GO:0007166 cell surface receptor signaling pathway; GO:0098542 defense response to other organism; GO:0060263 regulation of respiratory burst; GO:0044699 single-organism process; GO:0051249 regulation of lymphocyte activation; GO:0044237 cellular metabolic process; GO:0048871 multicellular organismal homeostasis; GO:0009607 response to biotic stimulus; GO:0051234 establishment of localization; GO:0006909 phagocytosis; GO:0009605 response to external stimulus; GO:0006956 complement activation; GO:0008152 metabolic process; GO:0060267 positive regulation of respiratory burst; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0018298 protein-chromophore linkage; GO:0002250 adaptive immune response; GO:0006958 complement activation, classical pathway; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0019731 antibacterial humoral response; GO:0050851 antigen receptor-mediated signaling pathway; GO:0044765 single-organism transport; GO:0051716 cellular response to stimulus; GO:0006911 phagocytosis, engulfment; GO:0002443 leukocyte mediated immunity; GO:0006910 phagocytosis, recognition; GO:0003094 glomerular filtration; GO:0019730 antimicrobial humoral response; GO:0050864 regulation of B cell activation; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0051251 positive regulation of lymphocyte activation; GO:0048870 cell motility; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0050776 regulation of immune response; GO:0050853 B cell receptor signaling pathway; GO:0006810 transport; GO:0050865 regulation of cell activation; GO:0050900 leukocyte migration; GO:0050789 regulation of biological process; GO:0001895 retina homeostasis; GO:0001894 tissue homeostasis; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006464 cellular protein modification process; GO:0002682 regulation of immune system process; GO:0040011 locomotion; GO:0006952 defense response; GO:0036211 protein modification process; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0016477 cell migration; GO:0044707 single-multicellular organism process; GO:0002252 immune effector process; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0044267 cellular protein metabolic process; GO:0010324 membrane invagination; GO:0006959 humoral immune response; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0008037 cell recognition; GO:0060249 anatomical structure homeostasis; GO:0045087 innate immune response; GO:0019724 B cell mediated immunity; GO:0071704 organic substance metabolic process; GO:0099024 plasma membrane invagination; GO:0042592 homeostatic process; GO:0050867 positive regulation of cell activation; GO:1902578 single-organism localization; GO:0050871 positive regulation of B cell activation; GO:0002757 immune response-activating signal transduction; GO:0006898 receptor-mediated endocytosis; GO:0002449 lymphocyte mediated immunity; GO:0009987 cellular process; GO:0050778 positive regulation of immune response; GO:0009617 response to bacterium; GO:0002253 activation of immune response; GO:0003008 system process; GO:0006950 response to stress; GO:0042742 defense response to bacterium; GO:0003014 renal system process; GO:0016192 vesicle-mediated transport; GO:0072376 protein activation cascade; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0002696 positive regulation of leukocyte activation; GO:0061024 membrane organization; GO:0002684 positive regulation of immune system process; GO:0006928 movement of cell or subcellular component; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0043412 macromolecule modification; GO:0006955 immune response; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:0097205 renal filtration; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0009897 external side of plasma membrane; GO:0071944 cell periphery; GO:0042571 immunoglobulin complex, circulating; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0005623 cell; GO:0071746 IgA immunoglobulin complex, circulating; GO:0070062 extracellular exosome; GO:0071750 dimeric IgA immunoglobulin complex; GO:0044464 cell part; GO:0044425 membrane part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0098552 side of membrane; GO:0019814 immunoglobulin complex; GO:0005576 extracellular region; GO:0071745 IgA immunoglobulin complex; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0072562 blood microparticle; GO:0044459 plasma membrane part; GO:0071749 polymeric IgA immunoglobulin complex; GO:0071751 secretory IgA immunoglobulin complex; GO:0071752 secretory dimeric IgA immunoglobulin complex; GO:0009986 cell surface; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0071748 monomeric IgA immunoglobulin complex; ","GO:0005515 protein binding; GO:0003823 antigen binding; GO:0005488 binding; ",{"$nulls":3},"IPR007110; IPR013783; IPR003597; ","Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin C1-set; \r"]
["P01903","HLA class II histocompatibility antigen, DR alpha chain OS=Homo sapiens OX=9606 GN=HLA-DRA","HLA-DRA",28.607,77.089,32.3,6,12,6,0.97,0.918,0.891,1.054,1.052,1.072,1.144,0.00624,"extracellular\r","GO:0050863 regulation of T cell activation; GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0002694 regulation of leukocyte activation; GO:0007166 cell surface receptor signaling pathway; GO:0071346 cellular response to interferon-gamma; GO:0044699 single-organism process; GO:0031294 lymphocyte costimulation; GO:0044764 multi-organism cellular process; GO:0051249 regulation of lymphocyte activation; GO:0071345 cellular response to cytokine stimulus; GO:0050877 neurological system process; GO:0060333 interferon-gamma-mediated signaling pathway; GO:0071823 protein-carbohydrate complex subunit organization; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0002503 peptide antigen assembly with MHC class II protein complex; GO:0044419 interspecies interaction between organisms; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0070887 cellular response to chemical stimulus; GO:0050851 antigen receptor-mediated signaling pathway; GO:0051716 cellular response to stimulus; GO:0071822 protein complex subunit organization; GO:0034097 response to cytokine; GO:0048002 antigen processing and presentation of peptide antigen; GO:0048522 positive regulation of cellular process; GO:0051251 positive regulation of lymphocyte activation; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0002495 antigen processing and presentation of peptide antigen via MHC class II; GO:0032501 multicellular organismal process; GO:0002505 antigen processing and presentation of polysaccharide antigen via MHC class II; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0050865 regulation of cell activation; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; GO:0002506 polysaccharide assembly with MHC class II protein complex; GO:0048583 regulation of response to stimulus; GO:0002396 MHC protein complex assembly; GO:0002682 regulation of immune system process; GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II; GO:0006952 defense response; GO:0070271 protein complex biogenesis; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0071310 cellular response to organic substance; GO:0050896 response to stimulus; GO:0045087 innate immune response; GO:0050867 positive regulation of cell activation; GO:0016032 viral process; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:0050890 cognition; GO:0002757 immune response-activating signal transduction; GO:0050778 positive regulation of immune response; GO:0019221 cytokine-mediated signaling pathway; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0043623 cellular protein complex assembly; GO:0002501 peptide antigen assembly with MHC protein complex; GO:0002253 activation of immune response; GO:0034622 cellular macromolecular complex assembly; GO:0003008 system process; GO:0006950 response to stress; GO:0002399 MHC class II protein complex assembly; GO:0045785 positive regulation of cell adhesion; GO:0022409 positive regulation of cell-cell adhesion; GO:0031295 T cell costimulation; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0034341 response to interferon-gamma; GO:0048518 positive regulation of biological process; GO:1903039 positive regulation of leukocyte cell-cell adhesion; GO:0030155 regulation of cell adhesion; GO:0022407 regulation of cell-cell adhesion; GO:0065006 protein-carbohydrate complex assembly; GO:0043933 macromolecular complex subunit organization; GO:0002696 positive regulation of leukocyte activation; GO:0019882 antigen processing and presentation; GO:0050852 T cell receptor signaling pathway; GO:0050870 positive regulation of T cell activation; GO:0002684 positive regulation of immune system process; GO:0048584 positive regulation of response to stimulus; GO:0006955 immune response; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0045334 clathrin-coated endocytic vesicle; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0032588 trans-Golgi network membrane; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0005765 lysosomal membrane; GO:0070062 extracellular exosome; GO:0042613 MHC class II protein complex; GO:0030136 clathrin-coated vesicle; GO:0031902 late endosome membrane; GO:0005622 intracellular; GO:0005764 lysosome; GO:0098791 Golgi subcompartment; GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0098552 side of membrane; GO:0000323 lytic vacuole; GO:0010008 endosome membrane; GO:0031226 intrinsic component of plasma membrane; GO:0005770 late endosome; GO:0030666 endocytic vesicle membrane; GO:0098797 plasma membrane protein complex; GO:0044440 endosomal part; GO:0012506 vesicle membrane; GO:0005576 extracellular region; GO:0030135 coated vesicle; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0098553 lumenal side of endoplasmic reticulum membrane; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0030176 integral component of endoplasmic reticulum membrane; GO:0043234 protein complex; GO:0030133 transport vesicle; GO:0043230 extracellular organelle; GO:0030658 transport vesicle membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0042611 MHC protein complex; GO:0031982 vesicle; GO:0030669 clathrin-coated endocytic vesicle membrane; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0030662 coated vesicle membrane; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0031227 intrinsic component of endoplasmic reticulum membrane; GO:0044431 Golgi apparatus part; GO:0005768 endosome; GO:0030139 endocytic vesicle; GO:0012507 ER to Golgi transport vesicle membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0030134 ER to Golgi transport vesicle; GO:0012505 endomembrane system; GO:0030665 clathrin-coated vesicle membrane; GO:0016021 integral component of membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0044432 endoplasmic reticulum part; GO:0005802 trans-Golgi network; GO:0005774 vacuolar membrane; GO:0009986 cell surface; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; GO:0031984 organelle subcompartment; ","GO:0038023 signaling receptor activity; GO:0044877 macromolecular complex binding; GO:0005515 protein binding; GO:0033218 amide binding; GO:0004888 transmembrane signaling receptor activity; GO:0004871 signal transducer activity; GO:0032395 MHC class II receptor activity; GO:0003823 antigen binding; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0042277 peptide binding; GO:0005488 binding; GO:0023023 MHC protein complex binding; GO:0023026 MHC class II protein complex binding; GO:0042605 peptide antigen binding; GO:0099600 transmembrane receptor activity; GO:0032403 protein complex binding; ","K06752","MHC2; major histocompatibility complex, class II","hsa05330 Allograft rejection - Homo sapiens (human); hsa05322 Systemic lupus erythematosus - Homo sapiens (human); hsa04672 Intestinal immune network for IgA production - Homo sapiens (human); hsa05152 Tuberculosis - Homo sapiens (human); hsa05150 Staphylococcus aureus infection - Homo sapiens (human); hsa05323 Rheumatoid arthritis - Homo sapiens (human); hsa05168 Herpes simplex infection - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); hsa05140 Leishmaniasis - Homo sapiens (human); hsa04640 Hematopoietic cell lineage - Homo sapiens (human); hsa05166 HTLV-I infection - Homo sapiens (human); hsa04940 Type I diabetes mellitus - Homo sapiens (human); hsa04514 Cell adhesion molecules (CAMs) - Homo sapiens (human); hsa04658 Th1 and Th2 cell differentiation - Homo sapiens (human); hsa05320 Autoimmune thyroid disease - Homo sapiens (human); hsa05164 Influenza A - Homo sapiens (human); hsa05145 Toxoplasmosis - Homo sapiens (human); hsa05310 Asthma - Homo sapiens (human); hsa04659 Th17 cell differentiation - Homo sapiens (human); hsa05321 Inflammatory bowel disease (IBD) - Homo sapiens (human); hsa05416 Viral myocarditis - Homo sapiens (human); hsa04612 Antigen processing and presentation - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); hsa05332 Graft-versus-host disease - Homo sapiens (human); ","IPR001003; IPR007110; IPR013783; IPR014745; IPR011162; IPR032431; IPR003597; ","\"MHC class II, alpha chain, N-terminal; Immunoglobulin-like domain; Immunoglobulin-like fold; MHC class II, alpha/beta chain, N-terminal; MHC classes I/II-like antigen recognition protein; Immunoglobulin C1-set, C-terminal extension; Immunoglobulin C1-set; \"\r"]
["P01909","HLA class II histocompatibility antigen, DQ alpha 1 chain OS=Homo sapiens OX=9606 GN=HLA-DQA1","HLA-DQA1",27.805,9.3272,9.4,2,3,2,0.545,0.709,0.716,1.474,1.163,1.362,2.03,3.3E-3,"extracellular\r","GO:0044700 single organism signaling; GO:0050863 regulation of T cell activation; GO:0002694 regulation of leukocyte activation; GO:0007166 cell surface receptor signaling pathway; GO:0071346 cellular response to interferon-gamma; GO:0044699 single-organism process; GO:0031294 lymphocyte costimulation; GO:0051249 regulation of lymphocyte activation; GO:0071345 cellular response to cytokine stimulus; GO:0060333 interferon-gamma-mediated signaling pathway; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0070887 cellular response to chemical stimulus; GO:0050851 antigen receptor-mediated signaling pathway; GO:0051716 cellular response to stimulus; GO:0034097 response to cytokine; GO:0048002 antigen processing and presentation of peptide antigen; GO:0048522 positive regulation of cellular process; GO:0051251 positive regulation of lymphocyte activation; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0002495 antigen processing and presentation of peptide antigen via MHC class II; GO:0050776 regulation of immune response; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0050865 regulation of cell activation; GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; GO:0048583 regulation of response to stimulus; GO:0002682 regulation of immune system process; GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II; GO:0006952 defense response; GO:0050794 regulation of cellular process; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0071310 cellular response to organic substance; GO:0050896 response to stimulus; GO:0045087 innate immune response; GO:0050867 positive regulation of cell activation; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:0002757 immune response-activating signal transduction; GO:0019221 cytokine-mediated signaling pathway; GO:0009987 cellular process; GO:0050778 positive regulation of immune response; GO:0002253 activation of immune response; GO:0006950 response to stress; GO:0045785 positive regulation of cell adhesion; GO:0022409 positive regulation of cell-cell adhesion; GO:0031295 T cell costimulation; GO:0002376 immune system process; GO:0034341 response to interferon-gamma; GO:0010033 response to organic substance; GO:0048518 positive regulation of biological process; GO:1903039 positive regulation of leukocyte cell-cell adhesion; GO:0030155 regulation of cell adhesion; GO:0022407 regulation of cell-cell adhesion; GO:0002696 positive regulation of leukocyte activation; GO:0019882 antigen processing and presentation; GO:0050852 T cell receptor signaling pathway; GO:0050870 positive regulation of T cell activation; GO:0002684 positive regulation of immune system process; GO:0006955 immune response; GO:0048584 positive regulation of response to stimulus; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0045334 clathrin-coated endocytic vesicle; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0032588 trans-Golgi network membrane; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0005765 lysosomal membrane; GO:0042613 MHC class II protein complex; GO:0030136 clathrin-coated vesicle; GO:0005622 intracellular; GO:0005764 lysosome; GO:0098791 Golgi subcompartment; GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0098552 side of membrane; GO:0000323 lytic vacuole; GO:0010008 endosome membrane; GO:0031226 intrinsic component of plasma membrane; GO:0030666 endocytic vesicle membrane; GO:0098797 plasma membrane protein complex; GO:0012506 vesicle membrane; GO:0044440 endosomal part; GO:0030135 coated vesicle; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0098553 lumenal side of endoplasmic reticulum membrane; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0030176 integral component of endoplasmic reticulum membrane; GO:0043234 protein complex; GO:0030133 transport vesicle; GO:0030658 transport vesicle membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0042611 MHC protein complex; GO:0030669 clathrin-coated endocytic vesicle membrane; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0030662 coated vesicle membrane; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0031227 intrinsic component of endoplasmic reticulum membrane; GO:0044431 Golgi apparatus part; GO:0005768 endosome; GO:0030139 endocytic vesicle; GO:0012507 ER to Golgi transport vesicle membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0030134 ER to Golgi transport vesicle; GO:0012505 endomembrane system; GO:0030665 clathrin-coated vesicle membrane; GO:0016021 integral component of membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0044432 endoplasmic reticulum part; GO:0005802 trans-Golgi network; GO:0005774 vacuolar membrane; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; GO:0031984 organelle subcompartment; ","GO:0038023 signaling receptor activity; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0042277 peptide binding; GO:0005488 binding; GO:0005515 protein binding; GO:0042605 peptide antigen binding; GO:0033218 amide binding; GO:0004888 transmembrane signaling receptor activity; GO:0004871 signal transducer activity; GO:0032395 MHC class II receptor activity; GO:0003823 antigen binding; GO:0099600 transmembrane receptor activity; ","K06752","MHC2; major histocompatibility complex, class II","hsa05330 Allograft rejection - Homo sapiens (human); hsa05322 Systemic lupus erythematosus - Homo sapiens (human); hsa04672 Intestinal immune network for IgA production - Homo sapiens (human); hsa05152 Tuberculosis - Homo sapiens (human); hsa05150 Staphylococcus aureus infection - Homo sapiens (human); hsa05323 Rheumatoid arthritis - Homo sapiens (human); hsa05168 Herpes simplex infection - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); hsa05140 Leishmaniasis - Homo sapiens (human); hsa04640 Hematopoietic cell lineage - Homo sapiens (human); hsa05166 HTLV-I infection - Homo sapiens (human); hsa04940 Type I diabetes mellitus - Homo sapiens (human); hsa04514 Cell adhesion molecules (CAMs) - Homo sapiens (human); hsa04658 Th1 and Th2 cell differentiation - Homo sapiens (human); hsa05320 Autoimmune thyroid disease - Homo sapiens (human); hsa05164 Influenza A - Homo sapiens (human); hsa05145 Toxoplasmosis - Homo sapiens (human); hsa05310 Asthma - Homo sapiens (human); hsa04659 Th17 cell differentiation - Homo sapiens (human); hsa05321 Inflammatory bowel disease (IBD) - Homo sapiens (human); hsa05416 Viral myocarditis - Homo sapiens (human); hsa04612 Antigen processing and presentation - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); hsa05332 Graft-versus-host disease - Homo sapiens (human); ","IPR001003; IPR007110; IPR014745; IPR013783; IPR011162; IPR003597; IPR032431; ","\"MHC class II, alpha chain, N-terminal; Immunoglobulin-like domain; MHC class II, alpha/beta chain, N-terminal; Immunoglobulin-like fold; MHC classes I/II-like antigen recognition protein; Immunoglobulin C1-set; Immunoglobulin C1-set, C-terminal extension; \"\r"]
["P01920","HLA class II histocompatibility antigen, DQ beta 1 chain OS=Homo sapiens OX=9606 GN=HLA-DQB1","HLA-DQB1",29.991,27.139,9.6,2,2,2,0.929,0.891,0.963,1.097,1.016,1.103,1.156,0.0142,"mitochondria\r","GO:0044700 single organism signaling; GO:0050863 regulation of T cell activation; GO:0002694 regulation of leukocyte activation; GO:0016064 immunoglobulin mediated immune response; GO:0007166 cell surface receptor signaling pathway; GO:0071346 cellular response to interferon-gamma; GO:0044699 single-organism process; GO:0031294 lymphocyte costimulation; GO:0051249 regulation of lymphocyte activation; GO:0071345 cellular response to cytokine stimulus; GO:0060333 interferon-gamma-mediated signaling pathway; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0002250 adaptive immune response; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0070887 cellular response to chemical stimulus; GO:0050851 antigen receptor-mediated signaling pathway; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0034097 response to cytokine; GO:0048002 antigen processing and presentation of peptide antigen; GO:0048522 positive regulation of cellular process; GO:0051251 positive regulation of lymphocyte activation; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0002495 antigen processing and presentation of peptide antigen via MHC class II; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0050776 regulation of immune response; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0050865 regulation of cell activation; GO:0002440 production of molecular mediator of immune response; GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; GO:0048583 regulation of response to stimulus; GO:0002381 immunoglobulin production involved in immunoglobulin mediated immune response; GO:0002682 regulation of immune system process; GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II; GO:0006952 defense response; GO:0050794 regulation of cellular process; GO:0002252 immune effector process; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0071310 cellular response to organic substance; GO:0006959 humoral immune response; GO:0050896 response to stimulus; GO:0045087 innate immune response; GO:0019724 B cell mediated immunity; GO:0050867 positive regulation of cell activation; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:0002757 immune response-activating signal transduction; GO:0002449 lymphocyte mediated immunity; GO:0050778 positive regulation of immune response; GO:0019221 cytokine-mediated signaling pathway; GO:0009987 cellular process; GO:0002253 activation of immune response; GO:0045785 positive regulation of cell adhesion; GO:0006950 response to stress; GO:0022409 positive regulation of cell-cell adhesion; GO:0031295 T cell costimulation; GO:0002376 immune system process; GO:0034341 response to interferon-gamma; GO:0010033 response to organic substance; GO:0048518 positive regulation of biological process; GO:1903039 positive regulation of leukocyte cell-cell adhesion; GO:0030155 regulation of cell adhesion; GO:0022407 regulation of cell-cell adhesion; GO:0002696 positive regulation of leukocyte activation; GO:0019882 antigen processing and presentation; GO:0050852 T cell receptor signaling pathway; GO:0002377 immunoglobulin production; GO:0050870 positive regulation of T cell activation; GO:0002684 positive regulation of immune system process; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0048584 positive regulation of response to stimulus; GO:0006955 immune response; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0045334 clathrin-coated endocytic vesicle; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0032588 trans-Golgi network membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0005765 lysosomal membrane; GO:0042613 MHC class II protein complex; GO:0030136 clathrin-coated vesicle; GO:0005622 intracellular; GO:0005764 lysosome; GO:0098791 Golgi subcompartment; GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0098552 side of membrane; GO:0000323 lytic vacuole; GO:0010008 endosome membrane; GO:0030666 endocytic vesicle membrane; GO:0098797 plasma membrane protein complex; GO:0012506 vesicle membrane; GO:0044440 endosomal part; GO:0030135 coated vesicle; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0098553 lumenal side of endoplasmic reticulum membrane; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0030176 integral component of endoplasmic reticulum membrane; GO:0043234 protein complex; GO:0030133 transport vesicle; GO:0030658 transport vesicle membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0042611 MHC protein complex; GO:0030669 clathrin-coated endocytic vesicle membrane; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0030662 coated vesicle membrane; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0031227 intrinsic component of endoplasmic reticulum membrane; GO:0044431 Golgi apparatus part; GO:0005768 endosome; GO:0030139 endocytic vesicle; GO:0012507 ER to Golgi transport vesicle membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0030134 ER to Golgi transport vesicle; GO:0012505 endomembrane system; GO:0030665 clathrin-coated vesicle membrane; GO:0016021 integral component of membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0044432 endoplasmic reticulum part; GO:0005802 trans-Golgi network; GO:0005774 vacuolar membrane; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; GO:0031984 organelle subcompartment; ","GO:0038023 signaling receptor activity; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0042277 peptide binding; GO:0005488 binding; GO:0005515 protein binding; GO:0042605 peptide antigen binding; GO:0033218 amide binding; GO:0004888 transmembrane signaling receptor activity; GO:0004871 signal transducer activity; GO:0032395 MHC class II receptor activity; GO:0003823 antigen binding; GO:0099600 transmembrane receptor activity; ","K06752","MHC2; major histocompatibility complex, class II","hsa05330 Allograft rejection - Homo sapiens (human); hsa05322 Systemic lupus erythematosus - Homo sapiens (human); hsa04672 Intestinal immune network for IgA production - Homo sapiens (human); hsa05152 Tuberculosis - Homo sapiens (human); hsa05150 Staphylococcus aureus infection - Homo sapiens (human); hsa05323 Rheumatoid arthritis - Homo sapiens (human); hsa05168 Herpes simplex infection - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); hsa05140 Leishmaniasis - Homo sapiens (human); hsa04640 Hematopoietic cell lineage - Homo sapiens (human); hsa05166 HTLV-I infection - Homo sapiens (human); hsa04940 Type I diabetes mellitus - Homo sapiens (human); hsa04514 Cell adhesion molecules (CAMs) - Homo sapiens (human); hsa04658 Th1 and Th2 cell differentiation - Homo sapiens (human); hsa05320 Autoimmune thyroid disease - Homo sapiens (human); hsa05164 Influenza A - Homo sapiens (human); hsa05145 Toxoplasmosis - Homo sapiens (human); hsa05310 Asthma - Homo sapiens (human); hsa04659 Th17 cell differentiation - Homo sapiens (human); hsa05321 Inflammatory bowel disease (IBD) - Homo sapiens (human); hsa05416 Viral myocarditis - Homo sapiens (human); hsa04612 Antigen processing and presentation - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); hsa05332 Graft-versus-host disease - Homo sapiens (human); ","IPR007110; IPR013783; IPR014745; IPR011162; IPR003597; IPR000353; ","\"Immunoglobulin-like domain; Immunoglobulin-like fold; MHC class II, alpha/beta chain, N-terminal; MHC classes I/II-like antigen recognition protein; Immunoglobulin C1-set; MHC class II, beta chain, N-terminal; \"\r"]
["P02042","Hemoglobin subunit delta OS=Homo sapiens OX=9606 GN=HBD","HBD",16.055,110.33,86.4,13,140,7,0.836,0.827,0.787,1.157,1.218,1.161,1.443,1.22E-4,"cytoplasm\r","GO:0015671 oxygen transport; GO:0044707 single-multicellular organism process; GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0015669 gas transport; GO:0050878 regulation of body fluid levels; GO:0006950 response to stress; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0032501 multicellular organismal process; GO:0007599 hemostasis; GO:0051234 establishment of localization; GO:0006810 transport; GO:0009611 response to wounding; GO:1902578 single-organism localization; GO:0042060 wound healing; GO:0050817 coagulation; GO:0051179 localization; GO:0065007 biological regulation; GO:0044765 single-organism transport; ","GO:0072562 blood microparticle; GO:0044421 extracellular region part; GO:0005615 extracellular space; GO:0044464 cell part; GO:0005622 intracellular; GO:0005833 hemoglobin complex; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044445 cytosolic part; GO:0044424 intracellular part; GO:0043234 protein complex; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0020037 heme binding; GO:0005506 iron ion binding; GO:0046914 transition metal ion binding; GO:0019825 oxygen binding; GO:0005488 binding; GO:0043167 ion binding; GO:0022892 substrate-specific transporter activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0005344 oxygen transporter activity; GO:0046906 tetrapyrrole binding; GO:0005215 transporter activity; ","K16151",null,null,"IPR009050; IPR000971; IPR012292; ","Globin-like; Globin; Globin/Protoglobin; \r"]
["P02144","Myoglobin OS=Homo sapiens OX=9606 GN=MB","MB",17.184,11.638,15.6,2,2,2,0.356,0.286,1.443,1.442,1.229,1.189,1.851,0.224,"cytoplasm\r","GO:0072359 circulatory system development; GO:0015671 oxygen transport; GO:0044707 single-multicellular organism process; GO:0065008 regulation of biological quality; GO:0003012 muscle system process; GO:0015669 gas transport; GO:0002262 myeloid cell homeostasis; GO:0009628 response to abiotic stimulus; GO:0048869 cellular developmental process; GO:1901700 response to oxygen-containing compound; GO:0044699 single-organism process; GO:0043353 enucleate erythrocyte differentiation; GO:0050896 response to stimulus; GO:0051234 establishment of localization; GO:0034101 erythrocyte homeostasis; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:0006936 muscle contraction; GO:0007507 heart development; GO:1902578 single-organism localization; GO:0001666 response to hypoxia; GO:0050881 musculoskeletal movement; GO:0070482 response to oxygen levels; GO:0006979 response to oxidative stress; GO:0009719 response to endogenous stimulus; GO:0031444 slow-twitch skeletal muscle fiber contraction; GO:0010035 response to inorganic substance; GO:0007275 multicellular organism development; GO:0050873 brown fat cell differentiation; GO:0009987 cellular process; GO:0044765 single-organism transport; GO:0032502 developmental process; GO:0003008 system process; GO:0030099 myeloid cell differentiation; GO:0006950 response to stress; GO:0048731 system development; GO:0000302 response to reactive oxygen species; GO:0044763 single-organism cellular process; GO:0050879 multicellular organismal movement; GO:0006941 striated muscle contraction; GO:0002376 immune system process; GO:0002520 immune system development; GO:0010033 response to organic substance; GO:0003010 voluntary skeletal muscle contraction; GO:0032501 multicellular organismal process; GO:0048534 hematopoietic or lymphoid organ development; GO:0030097 hemopoiesis; GO:0003009 skeletal muscle contraction; GO:0048872 homeostasis of number of cells; GO:0006810 transport; GO:0048513 animal organ development; GO:0042221 response to chemical; GO:0044767 single-organism developmental process; GO:0042542 response to hydrogen peroxide; GO:0030218 erythrocyte differentiation; GO:0045444 fat cell differentiation; GO:0036293 response to decreased oxygen levels; GO:0009725 response to hormone; GO:0014721 twitch skeletal muscle contraction; GO:0051179 localization; GO:0048856 anatomical structure development; GO:0065007 biological regulation; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0020037 heme binding; GO:0019825 oxygen binding; GO:0005488 binding; GO:0043167 ion binding; GO:0022892 substrate-specific transporter activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005344 oxygen transporter activity; GO:0046906 tetrapyrrole binding; GO:0005215 transporter activity; ",{"$nulls":3},"IPR009050; IPR000971; IPR012292; ","Globin-like; Globin; Globin/Protoglobin; \r"]
["P02452","Collagen alpha-1(I) chain OS=Homo sapiens OX=9606 GN=COL1A1","COL1A1",138.94,323.31,38.6,47,123,45,1.142,1.103,1.114,0.869,0.886,0.904,0.792,1.05E-4,"extracellular\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0030199 collagen fibril organization; GO:0043009 chordate embryonic development; GO:0009891 positive regulation of biosynthetic process; GO:0046683 response to organophosphorus; GO:0008152 metabolic process; GO:0065003 macromolecular complex assembly; GO:0060343 trabecula formation; GO:0090263 positive regulation of canonical Wnt signaling pathway; GO:0009790 embryo development; GO:0051716 cellular response to stimulus; GO:0043588 skin development; GO:0071214 cellular response to abiotic stimulus; GO:0060350 endochondral bone morphogenesis; GO:0080090 regulation of primary metabolic process; GO:0030168 platelet activation; GO:0044763 single-organism cellular process; GO:0060828 regulation of canonical Wnt signaling pathway; GO:0038065 collagen-activated signaling pathway; GO:0048870 cell motility; GO:0071559 response to transforming growth factor beta; GO:0071396 cellular response to lipid; GO:0050776 regulation of immune response; GO:0051291 protein heterooligomerization; GO:0006810 transport; GO:0010243 response to organonitrogen compound; GO:0051591 response to cAMP; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0036075 replacement ossification; GO:0010171 body morphogenesis; GO:0060325 face morphogenesis; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0043589 skin morphogenesis; GO:0072359 circulatory system development; GO:0044707 single-multicellular organism process; GO:1901700 response to oxygen-containing compound; GO:0048519 negative regulation of biological process; GO:0042493 response to drug; GO:0009653 anatomical structure morphogenesis; GO:0071229 cellular response to acid chemical; GO:0009889 regulation of biosynthetic process; GO:2000145 regulation of cell motility; GO:0043062 extracellular structure organization; GO:0070482 response to oxygen levels; GO:1902680 positive regulation of RNA biosynthetic process; GO:0031214 biomineral tissue development; GO:0034613 cellular protein localization; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0044711 single-organism biosynthetic process; GO:0006950 response to stress; GO:0051270 regulation of cellular component movement; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0007584 response to nutrient; GO:1901576 organic substance biosynthetic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0034505 tooth mineralization; GO:0060348 bone development; GO:0010718 positive regulation of epithelial to mesenchymal transition; GO:0042542 response to hydrogen peroxide; GO:0031325 positive regulation of cellular metabolic process; GO:0030177 positive regulation of Wnt signaling pathway; GO:0032963 collagen metabolic process; GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway; GO:0051674 localization of cell; GO:0051216 cartilage development; GO:0001568 blood vessel development; GO:0040017 positive regulation of locomotion; GO:0071306 cellular response to vitamin E; GO:0048869 cellular developmental process; GO:0032964 collagen biosynthetic process; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0033197 response to vitamin E; GO:0009611 response to wounding; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0034612 response to tumor necrosis factor; GO:0030198 extracellular matrix organization; GO:0033036 macromolecule localization; GO:0033273 response to vitamin; GO:0043200 response to amino acid; GO:0034097 response to cytokine; GO:0031326 regulation of cellular biosynthetic process; GO:0001944 vasculature development; GO:0023052 signaling; GO:0042476 odontogenesis; GO:0036296 response to increased oxygen levels; GO:0071417 cellular response to organonitrogen compound; GO:0070271 protein complex biogenesis; GO:0016477 cell migration; GO:0016043 cellular component organization; GO:0071260 cellular response to mechanical stimulus; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0031669 cellular response to nutrient levels; GO:0071704 organic substance metabolic process; GO:0071295 cellular response to vitamin; GO:0009612 response to mechanical stimulus; GO:0033993 response to lipid; GO:0030154 cell differentiation; GO:0044243 multicellular organismal catabolic process; GO:0060349 bone morphogenesis; GO:0060323 head morphogenesis; GO:0023056 positive regulation of signaling; GO:0031960 response to corticosteroid; GO:0010647 positive regulation of cell communication; GO:0009059 macromolecule biosynthetic process; GO:0045595 regulation of cell differentiation; GO:0070206 protein trimerization; GO:0006355 regulation of transcription, DNA-templated; GO:0050878 regulation of body fluid levels; GO:0009792 embryo development ending in birth or egg hatching; GO:1902618 cellular response to fluoride; GO:0043933 macromolecular complex subunit organization; GO:1901701 cellular response to oxygen-containing compound; GO:0071495 cellular response to endogenous stimulus; GO:0034504 protein localization to nucleus; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; GO:0001649 osteoblast differentiation; GO:0030335 positive regulation of cell migration; GO:0065008 regulation of biological quality; GO:0007596 blood coagulation; GO:0010717 regulation of epithelial to mesenchymal transition; GO:0007166 cell surface receptor signaling pathway; GO:0007601 visual perception; GO:0071345 cellular response to cytokine stimulus; GO:0050877 neurological system process; GO:0015031 protein transport; GO:0009605 response to external stimulus; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0048545 response to steroid hormone; GO:0009719 response to endogenous stimulus; GO:0070848 response to growth factor; GO:0033365 protein localization to organelle; GO:0043170 macromolecule metabolic process; GO:0061448 connective tissue development; GO:0008104 protein localization; GO:0048706 embryonic skeletal system development; GO:0044259 multicellular organismal macromolecule metabolic process; GO:1901652 response to peptide; GO:0030574 collagen catabolic process; GO:0014070 response to organic cyclic compound; GO:0001503 ossification; GO:0000302 response to reactive oxygen species; GO:0045893 positive regulation of transcription, DNA-templated; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0051272 positive regulation of cellular component movement; GO:0060346 bone trabecula formation; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0061383 trabecula morphogenesis; GO:0001958 endochondral ossification; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0050900 leukocyte migration; GO:0044710 single-organism metabolic process; GO:0032526 response to retinoic acid; GO:0071364 cellular response to epidermal growth factor stimulus; GO:0071230 cellular response to amino acid stimulus; GO:0010604 positive regulation of macromolecule metabolic process; GO:0009887 animal organ morphogenesis; GO:0002682 regulation of immune system process; GO:0050817 coagulation; GO:0097435 supramolecular fiber organization; GO:0051094 positive regulation of developmental process; GO:0050794 regulation of cellular process; GO:0007162 negative regulation of cell adhesion; GO:0061430 bone trabecula morphogenesis; GO:0009628 response to abiotic stimulus; GO:0032355 response to estradiol; GO:2000147 positive regulation of cell motility; GO:0048523 negative regulation of cellular process; GO:0045597 positive regulation of cell differentiation; GO:0051239 regulation of multicellular organismal process; GO:0051259 protein oligomerization; GO:0010628 positive regulation of gene expression; GO:0014074 response to purine-containing compound; GO:0071774 response to fibroblast growth factor; GO:0051171 regulation of nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0055093 response to hyperoxia; GO:0009966 regulation of signal transduction; GO:0006461 protein complex assembly; GO:0051254 positive regulation of RNA metabolic process; GO:0048731 system development; GO:0071496 cellular response to external stimulus; GO:0071407 cellular response to organic cyclic compound; GO:0072358 cardiovascular system development; GO:0030334 regulation of cell migration; GO:0071702 organic substance transport; GO:0030155 regulation of cell adhesion; GO:0031668 cellular response to extracellular stimulus; GO:0048705 skeletal system morphogenesis; GO:1902617 response to fluoride; GO:0045184 establishment of protein localization; GO:0030111 regulation of Wnt signaling pathway; GO:0031670 cellular response to nutrient; GO:0001775 cell activation; GO:0006928 movement of cell or subcellular component; GO:0007605 sensory perception of sound; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:0031328 positive regulation of cellular biosynthetic process; GO:0010810 regulation of cell-substrate adhesion; GO:0050793 regulation of developmental process; GO:0001101 response to acid chemical; GO:0071560 cellular response to transforming growth factor beta stimulus; GO:0044236 multicellular organism metabolic process; GO:0071363 cellular response to growth factor stimulus; GO:0036072 direct ossification; GO:0051234 establishment of localization; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0006979 response to oxidative stress; GO:0071300 cellular response to retinoic acid; GO:0060322 head development; GO:0010035 response to inorganic substance; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0007600 sensory perception; GO:0071822 protein complex subunit organization; GO:0009888 tissue development; GO:0048522 positive regulation of cellular process; GO:0060351 cartilage development involved in endochondral bone morphogenesis; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0043434 response to peptide hormone; GO:0001957 intramembranous ossification; GO:1901699 cellular response to nitrogen compound; GO:0019222 regulation of metabolic process; GO:0040011 locomotion; GO:0010812 negative regulation of cell-substrate adhesion; GO:0048856 anatomical structure development; GO:0001501 skeletal system development; GO:0050954 sensory perception of mechanical stimulus; GO:2000026 regulation of multicellular organismal development; GO:0060324 face development; GO:0071356 cellular response to tumor necrosis factor; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0050896 response to stimulus; GO:0007599 hemostasis; GO:0009991 response to extracellular stimulus; GO:0044691 tooth eruption; GO:0009987 cellular process; GO:0003008 system process; GO:0070849 response to epidermal growth factor; GO:0044712 single-organism catabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0050953 sensory perception of light stimulus; GO:0070208 protein heterotrimerization; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0051641 cellular localization; GO:0070727 cellular macromolecule localization; GO:0042060 wound healing; GO:0044767 single-organism developmental process; GO:0044344 cellular response to fibroblast growth factor stimulus; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0009967 positive regulation of signal transduction; GO:0031667 response to nutrient levels; GO:0009725 response to hormone; GO:0040012 regulation of locomotion; GO:0065007 biological regulation; ","GO:0005584 collagen type I trimer; GO:0005783 endoplasmic reticulum; GO:0005615 extracellular space; GO:0098643 banded collagen fibril; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0005583 fibrillar collagen trimer; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0044420 extracellular matrix component; GO:0044422 organelle part; GO:0005581 collagen trimer; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0005788 endoplasmic reticulum lumen; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098644 complex of collagen trimers; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0099081 supramolecular polymer; GO:0031012 extracellular matrix; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044432 endoplasmic reticulum part; GO:0005578 proteinaceous extracellular matrix; GO:0005794 Golgi apparatus; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0005201 extracellular matrix structural constituent; GO:0042802 identical protein binding; GO:0019838 growth factor binding; GO:0005488 binding; GO:0043167 ion binding; GO:0048407 platelet-derived growth factor binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0005198 structural molecule activity; ","K06236","COL1A; collagen, type I, alpha","hsa04933 AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa05146 Amoebiasis - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa04611 Platelet activation - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa04512 ECM-receptor interaction - Homo sapiens (human); hsa04974 Protein digestion and absorption - Homo sapiens (human); hsa04926 Relaxin signaling pathway - Homo sapiens (human); ","IPR001007; IPR000885; ","\"VWFC domain; Fibrillar collagen, C-terminal; \"\r"]
["P02461","Collagen alpha-1(III) chain OS=Homo sapiens OX=9606 GN=COL3A1","COL3A1",138.56,164.06,20.2,26,46,17,1.081,1.066,1.112,0.926,0.935,0.912,0.851,0.00036,"extracellular\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0007596 blood coagulation; GO:0030199 collagen fibril organization; GO:0007166 cell surface receptor signaling pathway; GO:0007420 brain development; GO:0060415 muscle tissue morphogenesis; GO:0021987 cerebral cortex development; GO:0044237 cellular metabolic process; GO:0021537 telencephalon development; GO:0022610 biological adhesion; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0007507 heart development; GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0032879 regulation of localization; GO:0007160 cell-matrix adhesion; GO:0009719 response to endogenous stimulus; GO:0007155 cell adhesion; GO:0070848 response to growth factor; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044259 multicellular organismal macromolecule metabolic process; GO:0051056 regulation of small GTPase mediated signal transduction; GO:0030574 collagen catabolic process; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0043588 skin development; GO:0030168 platelet activation; GO:0048699 generation of neurons; GO:0060537 muscle tissue development; GO:0044763 single-organism cellular process; GO:2000146 negative regulation of cell motility; GO:0071559 response to transforming growth factor beta; GO:0032501 multicellular organismal process; GO:0050776 regulation of immune response; GO:0050768 negative regulation of neurogenesis; GO:0010243 response to organonitrogen compound; GO:0048513 animal organ development; GO:0044710 single-organism metabolic process; GO:0007417 central nervous system development; GO:0071230 cellular response to amino acid stimulus; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0048644 muscle organ morphogenesis; GO:0044260 cellular macromolecule metabolic process; GO:0009887 animal organ morphogenesis; GO:0048844 artery morphogenesis; GO:0002682 regulation of immune system process; GO:0006464 cellular protein modification process; GO:0050817 coagulation; GO:0010721 negative regulation of cell development; GO:0097435 supramolecular fiber organization; GO:0072359 circulatory system development; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0009628 response to abiotic stimulus; GO:1901700 response to oxygen-containing compound; GO:0044267 cellular protein metabolic process; GO:0018149 peptide cross-linking; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0051239 regulation of multicellular organismal process; GO:0009653 anatomical structure morphogenesis; GO:0071229 cellular response to acid chemical; GO:2000145 regulation of cell motility; GO:0043062 extracellular structure organization; GO:0061061 muscle structure development; GO:0030900 forebrain development; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:1902531 regulation of intracellular signal transduction; GO:0006950 response to stress; GO:0051270 regulation of cellular component movement; GO:0051057 positive regulation of small GTPase mediated signal transduction; GO:0048731 system development; GO:0051960 regulation of nervous system development; GO:0060284 regulation of cell development; GO:0035909 aorta morphogenesis; GO:0007179 transforming growth factor beta receptor signaling pathway; GO:0055123 digestive system development; GO:0030334 regulation of cell migration; GO:0072358 cardiovascular system development; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0030336 negative regulation of cell migration; GO:0048565 digestive tract development; GO:0032963 collagen metabolic process; GO:0001775 cell activation; GO:2001222 regulation of neuron migration; GO:0048584 positive regulation of response to stimulus; GO:0043412 macromolecule modification; GO:0050793 regulation of developmental process; GO:0035023 regulation of Rho protein signal transduction; GO:0051093 negative regulation of developmental process; GO:0001101 response to acid chemical; GO:0001568 blood vessel development; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0044236 multicellular organism metabolic process; GO:0071560 cellular response to transforming growth factor beta stimulus; GO:0022008 neurogenesis; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0071363 cellular response to growth factor stimulus; GO:0040013 negative regulation of locomotion; GO:0009611 response to wounding; GO:0048729 tissue morphogenesis; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0060322 head development; GO:0050777 negative regulation of immune response; GO:0009314 response to radiation; GO:0048514 blood vessel morphogenesis; GO:0030198 extracellular matrix organization; GO:0045596 negative regulation of cell differentiation; GO:0070887 cellular response to chemical stimulus; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0032502 developmental process; GO:0043200 response to amino acid; GO:0035295 tube development; GO:0071822 protein complex subunit organization; GO:0009888 tissue development; GO:0034097 response to cytokine; GO:0001944 vasculature development; GO:0048522 positive regulation of cellular process; GO:0046579 positive regulation of Ras protein signal transduction; GO:0023052 signaling; GO:0007229 integrin-mediated signaling pathway; GO:0035904 aorta development; GO:0071417 cellular response to organonitrogen compound; GO:0002683 negative regulation of immune system process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:1901699 cellular response to nitrogen compound; GO:0007517 muscle organ development; GO:0060840 artery development; GO:0007568 aging; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0001501 skeletal system development; GO:2000026 regulation of multicellular organismal development; GO:0051271 negative regulation of cellular component movement; GO:0021543 pallium development; GO:0016043 cellular component organization; GO:0071310 cellular response to organic substance; GO:0046578 regulation of Ras protein signal transduction; GO:0050896 response to stimulus; GO:0007599 hemostasis; GO:0071704 organic substance metabolic process; GO:0009612 response to mechanical stimulus; GO:0030154 cell differentiation; GO:0044243 multicellular organismal catabolic process; GO:0051961 negative regulation of nervous system development; GO:0023056 positive regulation of signaling; GO:0035025 positive regulation of Rho protein signal transduction; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0050878 regulation of body fluid levels; GO:0048745 smooth muscle tissue development; GO:0044712 single-organism catabolic process; GO:0048585 negative regulation of response to stimulus; GO:0048518 positive regulation of biological process; GO:0043933 macromolecular complex subunit organization; GO:1901701 cellular response to oxygen-containing compound; GO:0042060 wound healing; GO:0060414 aorta smooth muscle tissue morphogenesis; GO:0031589 cell-substrate adhesion; GO:0044767 single-organism developmental process; GO:0071495 cellular response to endogenous stimulus; GO:2001223 negative regulation of neuron migration; GO:0009967 positive regulation of signal transduction; GO:0040012 regulation of locomotion; GO:0009056 catabolic process; GO:0050767 regulation of neurogenesis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0098643 banded collagen fibril; GO:0005783 endoplasmic reticulum; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0005583 fibrillar collagen trimer; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0044420 extracellular matrix component; GO:0044422 organelle part; GO:0005581 collagen trimer; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005788 endoplasmic reticulum lumen; GO:0098644 complex of collagen trimers; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0099081 supramolecular polymer; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031012 extracellular matrix; GO:0044432 endoplasmic reticulum part; GO:0005578 proteinaceous extracellular matrix; GO:0043234 protein complex; GO:0005586 collagen type III trimer; GO:0044444 cytoplasmic part; ","GO:0005102 receptor binding; GO:0019838 growth factor binding; GO:0043167 ion binding; GO:0044877 macromolecular complex binding; GO:0048407 platelet-derived growth factor binding; GO:0005515 protein binding; GO:0005178 integrin binding; GO:0050839 cell adhesion molecule binding; GO:0005201 extracellular matrix structural constituent; GO:0005488 binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005198 structural molecule activity; GO:0046332 SMAD binding; GO:0032403 protein complex binding; ","K19720","COL3A; collagen, type III, alpha","hsa04611 Platelet activation - Homo sapiens (human); hsa04974 Protein digestion and absorption - Homo sapiens (human); hsa04933 AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human); hsa04926 Relaxin signaling pathway - Homo sapiens (human); hsa05146 Amoebiasis - Homo sapiens (human); ","IPR001007; IPR000885; ","\"VWFC domain; Fibrillar collagen, C-terminal; \"\r"]
["P02462","Collagen alpha-1(IV) chain OS=Homo sapiens OX=9606 GN=COL4A1","COL4A1",160.61,41.173,4,5,13,5,1.067,1.14,1.134,0.892,1.007,0.905,0.839,0.0157,"extracellular\r","GO:0044700 single organism signaling; GO:0007528 neuromuscular junction development; GO:0001101 response to acid chemical; GO:0061333 renal tubule morphogenesis; GO:0007166 cell surface receptor signaling pathway; GO:0001568 blood vessel development; GO:0007420 brain development; GO:0048869 cellular developmental process; GO:0044236 multicellular organism metabolic process; GO:0044699 single-organism process; GO:0048754 branching morphogenesis of an epithelial tube; GO:0071711 basement membrane organization; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0001525 angiogenesis; GO:0048729 tissue morphogenesis; GO:0007154 cell communication; GO:0009719 response to endogenous stimulus; GO:0060322 head development; GO:0043170 macromolecule metabolic process; GO:0030198 extracellular matrix organization; GO:0048514 blood vessel morphogenesis; GO:0044259 multicellular organismal macromolecule metabolic process; GO:0001569 branching involved in blood vessel morphogenesis; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0070887 cellular response to chemical stimulus; GO:0030574 collagen catabolic process; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0043200 response to amino acid; GO:0051716 cellular response to stimulus; GO:0035295 tube development; GO:0060429 epithelium development; GO:0009888 tissue development; GO:0001763 morphogenesis of a branching structure; GO:0035239 tube morphogenesis; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0001944 vasculature development; GO:0038065 collagen-activated signaling pathway; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0071417 cellular response to organonitrogen compound; GO:0010243 response to organonitrogen compound; GO:0048513 animal organ development; GO:0001655 urogenital system development; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:1901699 cellular response to nitrogen compound; GO:0044710 single-organism metabolic process; GO:0007417 central nervous system development; GO:0071230 cellular response to amino acid stimulus; GO:1901698 response to nitrogen compound; GO:0048856 anatomical structure development; GO:0030855 epithelial cell differentiation; GO:0050794 regulation of cellular process; GO:0072359 circulatory system development; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0002009 morphogenesis of an epithelium; GO:0043010 camera-type eye development; GO:0061304 retinal blood vessel morphogenesis; GO:0071310 cellular response to organic substance; GO:1901700 response to oxygen-containing compound; GO:0072001 renal system development; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0009653 anatomical structure morphogenesis; GO:0044243 multicellular organismal catabolic process; GO:0030154 cell differentiation; GO:0001654 eye development; GO:0071229 cellular response to acid chemical; GO:0043062 extracellular structure organization; GO:0061299 retina vasculature morphogenesis in camera-type eye; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0061298 retina vasculature development in camera-type eye; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0060041 retina development in camera-type eye; GO:0060562 epithelial tube morphogenesis; GO:0044712 single-organism catabolic process; GO:0048731 system development; GO:0072358 cardiovascular system development; GO:0010033 response to organic substance; GO:0061326 renal tubule development; GO:0050808 synapse organization; GO:0061138 morphogenesis of a branching epithelium; GO:1901701 cellular response to oxygen-containing compound; GO:0044767 single-organism developmental process; GO:0071495 cellular response to endogenous stimulus; GO:0032963 collagen metabolic process; GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway; GO:0007423 sensory organ development; GO:0009056 catabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0005587 collagen type IV trimer; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0044420 extracellular matrix component; GO:0005581 collagen trimer; GO:0044422 organelle part; GO:0005604 basement membrane; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005788 endoplasmic reticulum lumen; GO:0098644 complex of collagen trimers; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0099081 supramolecular polymer; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031012 extracellular matrix; GO:0044432 endoplasmic reticulum part; GO:0098651 basement membrane collagen trimer; GO:0005578 proteinaceous extracellular matrix; GO:0043234 protein complex; GO:0098645 collagen network; GO:0098642 network-forming collagen trimer; GO:0044444 cytoplasmic part; ","GO:0005201 extracellular matrix structural constituent; GO:0019838 growth factor binding; GO:0005488 binding; GO:0048407 platelet-derived growth factor binding; GO:0030023 extracellular matrix constituent conferring elasticity; GO:0005515 protein binding; GO:0005198 structural molecule activity; GO:0097493 structural molecule activity conferring elasticity; ","K06237","COL4A; collagen, type IV, alpha","hsa05200 Pathways in cancer - Homo sapiens (human); hsa04933 AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa05146 Amoebiasis - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa05222 Small cell lung cancer - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa04512 ECM-receptor interaction - Homo sapiens (human); hsa04974 Protein digestion and absorption - Homo sapiens (human); hsa04926 Relaxin signaling pathway - Homo sapiens (human); ","IPR016187; ","C-type lectin fold; \r"]
["P02511","Alpha-crystallin B chain OS=Homo sapiens OX=9606 GN=CRYAB","CRYAB",20.159,37.163,35.4,7,18,7,1.22,1.192,1.121,0.82,0.837,0.816,0.7,0.000178,"mitochondria\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0003012 muscle system process; GO:0010941 regulation of cell death; GO:0031109 microtubule polymerization or depolymerization; GO:0051129 negative regulation of cellular component organization; GO:0044699 single-organism process; GO:0032459 regulation of protein oligomerization; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0031098 stress-activated protein kinase signaling cascade; GO:0001558 regulation of cell growth; GO:0006457 protein folding; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0032879 regulation of localization; GO:0065003 macromolecular complex assembly; GO:0006979 response to oxidative stress; GO:0009314 response to radiation; GO:0010035 response to inorganic substance; GO:0071479 cellular response to ionizing radiation; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0032387 negative regulation of intracellular transport; GO:0031333 negative regulation of protein complex assembly; GO:0032502 developmental process; GO:0051051 negative regulation of transport; GO:0045926 negative regulation of growth; GO:0051716 cellular response to stimulus; GO:0014070 response to organic cyclic compound; GO:0071822 protein complex subunit organization; GO:0071214 cellular response to abiotic stimulus; GO:0032460 negative regulation of protein oligomerization; GO:0080090 regulation of primary metabolic process; GO:0000302 response to reactive oxygen species; GO:1905906 regulation of amyloid fibril formation; GO:0044763 single-organism cellular process; GO:0032386 regulation of intracellular transport; GO:0023052 signaling; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0032501 multicellular organismal process; GO:1905907 negative regulation of amyloid fibril formation; GO:0030308 negative regulation of cell growth; GO:0000165 MAPK cascade; GO:0000226 microtubule cytoskeleton organization; GO:0043254 regulation of protein complex assembly; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0080135 regulation of cellular response to stress; GO:0071480 cellular response to gamma radiation; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:0007568 aging; GO:1902904 negative regulation of supramolecular fiber organization; GO:0044260 cellular macromolecule metabolic process; GO:1900034 regulation of cellular response to heat; GO:0019222 regulation of metabolic process; GO:0006464 cellular protein modification process; GO:0036211 protein modification process; GO:0070271 protein complex biogenesis; GO:2000377 regulation of reactive oxygen species metabolic process; GO:0060548 negative regulation of cell death; GO:1902903 regulation of supramolecular fiber organization; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0033554 cellular response to stress; GO:0016310 phosphorylation; GO:0040008 regulation of growth; GO:0043069 negative regulation of programmed cell death; GO:0051260 protein homooligomerization; GO:0009628 response to abiotic stimulus; GO:0060255 regulation of macromolecule metabolic process; GO:0010332 response to gamma radiation; GO:1901700 response to oxygen-containing compound; GO:0043067 regulation of programmed cell death; GO:0044267 cellular protein metabolic process; GO:0044087 regulation of cellular component biogenesis; GO:0032355 response to estradiol; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0051259 protein oligomerization; GO:0060341 regulation of cellular localization; GO:0071704 organic substance metabolic process; GO:0033993 response to lipid; GO:0006936 muscle contraction; GO:0006468 protein phosphorylation; GO:0043066 negative regulation of apoptotic process; GO:2000378 negative regulation of reactive oxygen species metabolic process; GO:0007010 cytoskeleton organization; GO:0071478 cellular response to radiation; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0051403 stress-activated MAPK cascade; GO:0023014 signal transduction by protein phosphorylation; GO:0003008 system process; GO:0006950 response to stress; GO:0035556 intracellular signal transduction; GO:0051049 regulation of transport; GO:0032462 regulation of protein homooligomerization; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0007017 microtubule-based process; GO:0009892 negative regulation of metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0010212 response to ionizing radiation; GO:0006793 phosphorus metabolic process; GO:0044767 single-organism developmental process; GO:0042542 response to hydrogen peroxide; GO:0051246 regulation of protein metabolic process; GO:0006996 organelle organization; GO:0032463 negative regulation of protein homooligomerization; GO:0051248 negative regulation of protein metabolic process; GO:0051128 regulation of cellular component organization; GO:0043412 macromolecule modification; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0030425 dendrite; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0043025 neuronal cell body; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0031674 I band; GO:0043197 dendritic spine; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0098590 plasma membrane region; GO:0005622 intracellular; GO:0014069 postsynaptic density; GO:0097060 synaptic membrane; GO:0043005 neuron projection; GO:0031430 M band; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043233 organelle lumen; GO:0042995 cell projection; GO:0044430 cytoskeletal part; GO:0031981 nuclear lumen; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0099081 supramolecular polymer; GO:0030424 axon; GO:0043231 intracellular membrane-bounded organelle; GO:0098794 postsynapse; GO:0031672 A band; GO:0043204 perikaryon; GO:0044449 contractile fiber part; GO:0099572 postsynaptic specialization; GO:0043230 extracellular organelle; GO:0071944 cell periphery; GO:0030016 myofibril; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0099512 supramolecular fiber; GO:0032432 actin filament bundle; GO:0032279 asymmetric synapse; GO:0005856 cytoskeleton; GO:0031974 membrane-enclosed lumen; GO:0044309 neuron spine; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0044464 cell part; GO:0044425 membrane part; GO:0043292 contractile fiber; GO:1903561 extracellular vesicle; GO:0098984 neuron to neuron synapse; GO:0044456 synapse part; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0097512 cardiac myofibril; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044463 cell projection part; GO:0015629 actin cytoskeleton; GO:0045202 synapse; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0030017 sarcomere; GO:0009986 cell surface; GO:0044297 cell body; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005212 structural constituent of eye lens; GO:0008092 cytoskeletal protein binding; GO:0042802 identical protein binding; GO:0042803 protein homodimerization activity; GO:0008017 microtubule binding; GO:0005488 binding; GO:0043167 ion binding; GO:0046983 protein dimerization activity; GO:0015631 tubulin binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0051082 unfolded protein binding; GO:0005198 structural molecule activity; ","K09542","CRYAB; crystallin, alpha B","hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); hsa04213 Longevity regulating pathway - multiple species - Homo sapiens (human); ","IPR002068; IPR003090; IPR008978; ","\"Alpha crystallin/Hsp20 domain; Alpha-crystallin, N-terminal; HSP20-like chaperone; \"\r"]
["P02545","Prelamin-A/C OS=Homo sapiens OX=9606 GN=LMNA","LMNA",74.139,323.31,64.8,46,134,44,1.124,1.137,1.142,0.866,0.877,0.864,0.766,1.15E-6,"nucleus\r","GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0090342 regulation of cell aging; GO:0090201 negative regulation of release of cytochrome c from mitochondria; GO:0009891 positive regulation of biosynthetic process; GO:0051169 nuclear transport; GO:0010821 regulation of mitochondrion organization; GO:0015031 protein transport; GO:0008285 negative regulation of cell proliferation; GO:0007507 heart development; GO:0035966 response to topologically incorrect protein; GO:0032879 regulation of localization; GO:0033365 protein localization to organelle; GO:0006606 protein import into nucleus; GO:0008104 protein localization; GO:0055013 cardiac muscle cell development; GO:0031468 nuclear envelope reassembly; GO:0044765 single-organism transport; GO:0007077 mitotic nuclear envelope disassembly; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0060537 muscle tissue development; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044763 single-organism cellular process; GO:0007163 establishment or maintenance of cell polarity; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0006810 transport; GO:0000226 microtubule cytoskeleton organization; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0055002 striated muscle cell development; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006913 nucleocytoplasmic transport; GO:0051094 positive regulation of developmental process; GO:0060548 negative regulation of cell death; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0055001 muscle cell development; GO:0072359 circulatory system development; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0046907 intracellular transport; GO:0033554 cellular response to stress; GO:0055006 cardiac cell development; GO:0042127 regulation of cell proliferation; GO:0034976 response to endoplasmic reticulum stress; GO:0009628 response to abiotic stimulus; GO:0032933 SREBP signaling pathway; GO:1902593 single-organism nuclear import; GO:0043067 regulation of programmed cell death; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0060341 regulation of cellular localization; GO:0055007 cardiac muscle cell differentiation; GO:0023057 negative regulation of signaling; GO:1902578 single-organism localization; GO:0010648 negative regulation of cell communication; GO:0051081 nuclear envelope disassembly; GO:2000145 regulation of cell motility; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0070482 response to oxygen levels; GO:0061061 muscle structure development; GO:0051171 regulation of nitrogen compound metabolic process; GO:0044744 protein targeting to nucleus; GO:1902580 single-organism cellular localization; GO:1902680 positive regulation of RNA biosynthetic process; GO:0032880 regulation of protein localization; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0034613 cellular protein localization; GO:0090343 positive regulation of cell aging; GO:0009966 regulation of signal transduction; GO:0071456 cellular response to hypoxia; GO:0055015 ventricular cardiac muscle cell development; GO:0006986 response to unfolded protein; GO:0051254 positive regulation of RNA metabolic process; GO:0010823 negative regulation of mitochondrion organization; GO:0035051 cardiocyte differentiation; GO:0006950 response to stress; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:2001237 negative regulation of extrinsic apoptotic signaling pathway; GO:0030334 regulation of cell migration; GO:0071702 organic substance transport; GO:0010033 response to organic substance; GO:0006984 ER-nucleus signaling pathway; GO:0007017 microtubule-based process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0045184 establishment of protein localization; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0031325 positive regulation of cellular metabolic process; GO:0010464 regulation of mesenchymal cell proliferation; GO:0036293 response to decreased oxygen levels; GO:0030952 establishment or maintenance of cytoskeleton polarity; GO:0051179 localization; GO:0031328 positive regulation of cellular biosynthetic process; GO:0050793 regulation of developmental process; GO:1903827 regulation of cellular protein localization; GO:0055012 ventricular cardiac muscle cell differentiation; GO:0010256 endomembrane system organization; GO:0072594 establishment of protein localization to organelle; GO:0009968 negative regulation of signal transduction; GO:0090199 regulation of release of cytochrome c from mitochondria; GO:0017038 protein import; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:0051129 negative regulation of cellular component organization; GO:0044699 single-organism process; GO:0030968 endoplasmic reticulum unfolded protein response; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:2001233 regulation of apoptotic signaling pathway; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0051649 establishment of localization in cell; GO:0072201 negative regulation of mesenchymal cell proliferation; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0007084 mitotic nuclear envelope reassembly; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0033036 macromolecule localization; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0009888 tissue development; GO:0031326 regulation of cellular biosynthetic process; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:1902582 single-organism intracellular transport; GO:0010639 negative regulation of organelle organization; GO:1902589 single-organism organelle organization; GO:0030397 membrane disassembly; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0007517 muscle organ development; GO:1900180 regulation of protein localization to nucleus; GO:2001236 regulation of extrinsic apoptotic signaling pathway; GO:0019222 regulation of metabolic process; GO:0048856 anatomical structure development; GO:0014706 striated muscle tissue development; GO:0006997 nucleus organization; GO:0016043 cellular component organization; GO:0043069 negative regulation of programmed cell death; GO:0048738 cardiac muscle tissue development; GO:0035967 cellular response to topologically incorrect protein; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0071310 cellular response to organic substance; GO:0035105 sterol regulatory element binding protein import into nucleus; GO:0036498 IRE1-mediated unfolded protein response; GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0006998 nuclear envelope organization; GO:0030154 cell differentiation; GO:0043066 negative regulation of apoptotic process; GO:0001666 response to hypoxia; GO:0006886 intracellular protein transport; GO:0071453 cellular response to oxygen levels; GO:0009987 cellular process; GO:0051146 striated muscle cell differentiation; GO:0006355 regulation of transcription, DNA-templated; GO:0034620 cellular response to unfolded protein; GO:0071501 cellular response to sterol depletion; GO:0006991 response to sterol depletion; GO:0044802 single-organism membrane organization; GO:0033043 regulation of organelle organization; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0051641 cellular localization; GO:0070727 cellular macromolecule localization; GO:0051170 nuclear import; GO:0044767 single-organism developmental process; GO:0042692 muscle cell differentiation; GO:0022411 cellular component disassembly; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0022402 cell cycle process; GO:0051128 regulation of cellular component organization; GO:0040012 regulation of locomotion; GO:0034504 protein localization to nucleus; GO:0036294 cellular response to decreased oxygen levels; GO:0007049 cell cycle; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0005652 nuclear lamina; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0031965 nuclear membrane; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0044464 cell part; GO:0005622 intracellular; GO:0048471 perinuclear region of cytoplasm; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005635 nuclear envelope; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0099081 supramolecular polymer; GO:0031012 extracellular matrix; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0045111 intermediate filament cytoskeleton; GO:0005882 intermediate filament; GO:0031975 envelope; GO:0005638 lamin filament; GO:0034399 nuclear periphery; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0042802 identical protein binding; GO:0005198 structural molecule activity; GO:0005488 binding; ","K12641","LMNA; lamin A/C","hsa05414 Dilated cardiomyopathy (DCM) - Homo sapiens (human); hsa04210 Apoptosis - Homo sapiens (human); hsa05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human); hsa05410 Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human); ","IPR001322; ","Lamin Tail Domain; \r"]
["P02549","Spectrin alpha chain, erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTA1","SPTA1",280.01,323.31,33.2,72,94,72,0.868,0.872,0.877,1.138,1.142,1.11,1.295,1.52E-5,"cytoplasm\r","GO:0044700 single organism signaling; GO:0002694 regulation of leukocyte activation; GO:0065008 regulation of biological quality; GO:0032944 regulation of mononuclear cell proliferation; GO:0032989 cellular component morphogenesis; GO:0030832 regulation of actin filament length; GO:0044237 cellular metabolic process; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0030036 actin cytoskeleton organization; GO:0032946 positive regulation of mononuclear cell proliferation; GO:0008360 regulation of cell shape; GO:0032535 regulation of cellular component size; GO:0044093 positive regulation of molecular function; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0051493 regulation of cytoskeleton organization; GO:0051099 positive regulation of binding; GO:0031333 negative regulation of protein complex assembly; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0002520 immune system development; GO:0048812 neuron projection morphogenesis; GO:0050670 regulation of lymphocyte proliferation; GO:0007009 plasma membrane organization; GO:0006935 chemotaxis; GO:0032501 multicellular organismal process; GO:0048872 homeostasis of number of cells; GO:0006810 transport; GO:0000902 cell morphogenesis; GO:0000165 MAPK cascade; GO:0048513 animal organ development; GO:0051336 regulation of hydrolase activity; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0030837 negative regulation of actin filament polymerization; GO:0042330 taxis; GO:0002682 regulation of immune system process; GO:0030834 regulation of actin filament depolymerization; GO:0033014 tetrapyrrole biosynthetic process; GO:0002260 lymphocyte homeostasis; GO:0097435 supramolecular fiber organization; GO:1901362 organic cyclic compound biosynthetic process; GO:1902903 regulation of supramolecular fiber organization; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0016310 phosphorylation; GO:0044707 single-multicellular organism process; GO:0042127 regulation of cell proliferation; GO:0032956 regulation of actin cytoskeleton organization; GO:0044267 cellular protein metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0009653 anatomical structure morphogenesis; GO:0050867 positive regulation of cell activation; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0051345 positive regulation of hydrolase activity; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0007409 axonogenesis; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0023014 signal transduction by protein phosphorylation; GO:0045785 positive regulation of cell adhesion; GO:0043547 positive regulation of GTPase activity; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0006779 porphyrin-containing compound biosynthetic process; GO:1901879 regulation of protein depolymerization; GO:0002376 immune system process; GO:0032970 regulation of actin filament-based process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:1903039 positive regulation of leukocyte cell-cell adhesion; GO:0030155 regulation of cell adhesion; GO:0008064 regulation of actin polymerization or depolymerization; GO:0030182 neuron differentiation; GO:0002696 positive regulation of leukocyte activation; GO:0006793 phosphorus metabolic process; GO:0097485 neuron projection guidance; GO:0050870 positive regulation of T cell activation; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0030029 actin filament-based process; GO:0006928 movement of cell or subcellular component; GO:0051179 localization; GO:0043412 macromolecule modification; GO:0050793 regulation of developmental process; GO:1901564 organonitrogen compound metabolic process; GO:0008284 positive regulation of cell proliferation; GO:0050863 regulation of T cell activation; GO:0030833 regulation of actin filament polymerization; GO:0051188 cofactor biosynthetic process; GO:0010256 endomembrane system organization; GO:0030835 negative regulation of actin filament depolymerization; GO:0032092 positive regulation of protein binding; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0051129 negative regulation of cellular component organization; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0009058 biosynthetic process; GO:0051249 regulation of lymphocyte activation; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0051693 actin filament capping; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0050671 positive regulation of lymphocyte proliferation; GO:0007154 cell communication; GO:0032990 cell part morphogenesis; GO:0070663 regulation of leukocyte proliferation; GO:0048858 cell projection morphogenesis; GO:0032271 regulation of protein polymerization; GO:0032502 developmental process; GO:0051494 negative regulation of cytoskeleton organization; GO:0051098 regulation of binding; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0051251 positive regulation of lymphocyte activation; GO:0001776 leukocyte homeostasis; GO:0023052 signaling; GO:0051186 cofactor metabolic process; GO:1902589 single-organism organelle organization; GO:0010639 negative regulation of organelle organization; GO:0050789 regulation of biological process; GO:0050865 regulation of cell activation; GO:0042221 response to chemical; GO:0043254 regulation of protein complex assembly; GO:0030030 cell projection organization; GO:0043242 negative regulation of protein complex disassembly; GO:0033013 tetrapyrrole metabolic process; GO:1902904 negative regulation of supramolecular fiber organization; GO:0065009 regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0040011 locomotion; GO:0043244 regulation of protein complex disassembly; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0042102 positive regulation of T cell proliferation; GO:0048193 Golgi vesicle transport; GO:0007015 actin filament organization; GO:0044087 regulation of cellular component biogenesis; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:0007411 axon guidance; GO:0048468 cell development; GO:0071704 organic substance metabolic process; GO:0000904 cell morphogenesis involved in differentiation; GO:1901880 negative regulation of protein depolymerization; GO:0042592 homeostatic process; GO:0043393 regulation of protein binding; GO:0006778 porphyrin-containing compound metabolic process; GO:0030154 cell differentiation; GO:0006468 protein phosphorylation; GO:0034641 cellular nitrogen compound metabolic process; GO:0009987 cellular process; GO:0035556 intracellular signal transduction; GO:0022409 positive regulation of cell-cell adhesion; GO:0044802 single-organism membrane organization; GO:0006807 nitrogen compound metabolic process; GO:0033043 regulation of organelle organization; GO:0042129 regulation of T cell proliferation; GO:0031175 neuron projection development; GO:0048518 positive regulation of biological process; GO:0048534 hematopoietic or lymphoid organ development; GO:0030097 hemopoiesis; GO:0044249 cellular biosynthetic process; GO:0022407 regulation of cell-cell adhesion; GO:0051641 cellular localization; GO:0043085 positive regulation of catalytic activity; GO:0061564 axon development; GO:0070665 positive regulation of leukocyte proliferation; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0044767 single-organism developmental process; GO:0002684 positive regulation of immune system process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0090066 regulation of anatomical structure size; GO:0051128 regulation of cellular component organization; GO:0032272 negative regulation of protein polymerization; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0022604 regulation of cell morphogenesis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005938 cell cortex; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0099568 cytoplasmic region; GO:0030863 cortical cytoskeleton; GO:0031224 intrinsic component of membrane; GO:0030864 cortical actin cytoskeleton; GO:0044424 intracellular part; GO:0005623 cell; GO:0009898 cytoplasmic side of plasma membrane; GO:0098562 cytoplasmic side of membrane; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0043005 neuron projection; GO:0008091 spectrin; GO:0097458 neuron part; GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane; GO:0098552 side of membrane; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0031226 intrinsic component of plasma membrane; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0005829 cytosol; GO:0015629 actin cytoskeleton; GO:0005886 plasma membrane; GO:0030424 axon; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0044448 cell cortex part; GO:0014731 spectrin-associated cytoskeleton; GO:0032437 cuticular plate; GO:0044444 cytoplasmic part; ","GO:0051015 actin filament binding; GO:0046982 protein heterodimerization activity; GO:0005085 guanyl-nucleotide exchange factor activity; GO:0043167 ion binding; GO:0046983 protein dimerization activity; GO:0044877 macromolecular complex binding; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0008092 cytoskeletal protein binding; GO:0005200 structural constituent of cytoskeleton; GO:0005488 binding; GO:0003779 actin binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005088 Ras guanyl-nucleotide exchange factor activity; GO:0005509 calcium ion binding; GO:0005198 structural molecule activity; GO:0032403 protein complex binding; ","K06114","SPTA; spectrin alpha","hsa04210 Apoptosis - Homo sapiens (human); ","IPR013315; IPR014837; IPR001452; IPR002048; IPR011992; ","\"Spectrin alpha chain, SH3 domain; EF-hand, Ca insensitive; SH3 domain; EF-hand domain; EF-hand domain pair; \"\r"]
["P02647","Apolipoprotein A-I OS=Homo sapiens OX=9606 GN=APOA1","APOA1",30.777,284.28,75.3,29,119,29,0.989,0.982,0.989,1.001,1.02,1.004,1.022,0.0262,"extracellular\r",{"$cut":{"chars":19022,"head":"GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0090130 tissue migration; GO:0048732 gland development; GO:0032371 regulation of sterol transport; GO:0006066 alcohol metabolic process; GO:0009891 positive regulation of biosynthetic process; GO:0002698 negative regulation of immune effector process; GO:0044255 cellular lipid metabolic process; GO:0070328 triglyceride homeostasis; GO:0050711 negative regulation of interleukin-1 secretion; GO:0031347 regulation of defense response; GO:0044237 cellular metabolic process; GO:0008610 lipid biosynthetic process; GO:0046461 neutral lipid catabolic process; GO:0008152 metabolic process; GO:0065003 macromolecular complex assembly; GO:0050996 positive regulation of lipid catabolic process; GO:0006639 acylglycerol metabolic process; GO:0044093 positive regulation of molecular function; GO:0071825 protein-lipid complex subunit organization; GO:0044057 regulation of system process; GO:0051180 vitamin transport; GO:0051493 regulation of cytoskeleton organization; GO:0018158 protein oxidation; GO:0032489 regulation of Cdc42 protein signal transduction; GO:0046889 positive regulation of lipid biosynthetic process; GO:0051051 negative regulation of transport; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0050709 negative regulation of protein secretion; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0060191 regulation of lipase activity; GO:1900026 positive regulation of substrate adhesion-dependent cell spreading; GO:0008202 steroid metabolic process; GO:0044763 single-organism cellular process; GO:1903531 negative regulation of secretion by cell; GO:0032692 negative regulation of interleukin-1 production; GO:0048870 cell motility; GO:0043086 negative regulation of catalytic activity; GO:0002740 negative regulation of cytokine secretion involved in immune response; GO:0006935 chemotaxis; GO:0010811 positive regulation of cell-substrate adhesion; GO:0050776 regulation of immune response; GO:0050673 epithelial cell proliferation; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0034377 plasma lipoprotein particle assembly; GO:0046890 regulation of lipid biosynthetic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0042304 regulation of fatty acid biosynthetic process; GO:1902905 positive regulation of supramolecular fiber organization; GO:0016101 diterpenoid metabolic process; GO:0051223 regulation of protein transport; GO:0032233 positive regulation of actin filament bundle assembly; GO:0046503 glycerolipid catabolic process; GO:0044707 single-multicellular organism process; GO:0010896 regulation of triglyceride catabolic process; GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway; GO:0002718 regulation of cytokine production involved in immune response; GO:0050728 negative regulation of inflammatory response; GO:1902653 secondary alcohol biosynthetic process; GO:0022408 negative regulation of cell-cell adhesion; GO:0002576 platelet degranulation; GO:0048519 negative regulation of biological process; GO:0042493 response to drug; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0051345 positive regulation of hydrolase activity; GO:0061365 positive regulation of triglyceride lipase activity; GO:0009889 regulation of biosynthetic process; GO:0009896 positive regulation of catabolic process; GO:0034369 plasma lipoprotein particle remodeling; GO:0044248 cellular catabolic process; GO:0034115 negative regulation of heterotypic cell-cell adhesion; GO:0033700 phospholipid efflux; GO:0051006 positive regulation of lipoprotein lipase activity; GO:0048878 chemical homeostasis; GO:0060192 negative regulation of lipase activity; GO:0010898 positive regulation of triglyceride catabolic process; GO:0006638 neutral lipid metabolic process; GO:0006950 response to stress; GO:0045785 positive regulation of cell adhesion; G"}},"GO:0034774 secretory granule lumen; GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0044421 extracellular region part; GO:0005615 extracellular space; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0034358 plasma lipoprotein particle; GO:0044433 cytoplasmic vesicle part; GO:0034385 triglyceride-rich plasma lipoprotein particle; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0034361 very-low-density lipoprotein particle; GO:0044422 organelle part; GO:0005769 early endosome; GO:0034365 discoidal high-density lipoprotein particle; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0032994 protein-lipid complex; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1990777 lipoprotein particle; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0030141 secretory granule; GO:0030139 endocytic vesicle; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0005788 endoplasmic reticulum lumen; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0042627 chylomicron; GO:0034364 high-density lipoprotein particle; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0072562 blood microparticle; GO:0060205 cytoplasmic vesicle lumen; GO:0044432 endoplasmic reticulum part; GO:0034366 spherical high-density lipoprotein particle; GO:0009986 cell surface; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0071682 endocytic vesicle lumen; ","GO:0032934 sterol binding; GO:0070405 ammonium ion binding; GO:0005102 receptor binding; GO:0034191 apolipoprotein A-I receptor binding; GO:0005319 lipid transporter activity; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0005496 steroid binding; GO:0097159 organic cyclic compound binding; GO:0031210 phosphatidylcholine binding; GO:0050997 quaternary ammonium group binding; GO:0042802 identical protein binding; GO:0042277 peptide binding; GO:0008035 high-density lipoprotein particle binding; GO:0005488 binding; GO:0015248 sterol transporter activity; GO:0008289 lipid binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0045499 chemorepellent activity; GO:0008047 enzyme activator activity; GO:0005548 phospholipid transporter activity; GO:0005215 transporter activity; GO:0015485 cholesterol binding; GO:0055102 lipase inhibitor activity; GO:0070653 high-density lipoprotein particle receptor binding; GO:0034190 apolipoprotein receptor binding; GO:0043167 ion binding; GO:0044877 macromolecular complex binding; GO:0071813 lipoprotein particle binding; GO:0033218 amide binding; GO:0001540 beta-amyloid binding; GO:0070325 lipoprotein particle receptor binding; GO:0030234 enzyme regulator activity; GO:0017127 cholesterol transporter activity; GO:0043178 alcohol binding; GO:0005543 phospholipid binding; GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity; GO:0071814 protein-lipid complex binding; GO:0019899 enzyme binding; GO:0036094 small molecule binding; ","K08757","APOA1; apolipoprotein A-I","hsa04975 Fat digestion and absorption - Homo sapiens (human); hsa03320 PPAR signaling pathway - Homo sapiens (human); hsa04977 Vitamin digestion and absorption - Homo sapiens (human); hsa04979 Cholesterol metabolism - Homo sapiens (human); hsa05143 African trypanosomiasis - Homo sapiens (human); "]
["P02649","Apolipoprotein E OS=Homo sapiens OX=9606 GN=APOE","APOE",36.154,101.89,59.6,20,39,20,1.022,1.031,1.037,0.956,0.966,0.993,0.943,0.00846,"extracellular\r",{"$cut":{"chars":28468,"head":"GO:0044700 single organism signaling; GO:1902430 negative regulation of beta-amyloid formation; GO:0006066 alcohol metabolic process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0001558 regulation of cell growth; GO:0046461 neutral lipid catabolic process; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0055065 metal ion homeostasis; GO:0098869 cellular oxidant detoxification; GO:0032489 regulation of Cdc42 protein signal transduction; GO:0044794 positive regulation by host of viral process; GO:0080090 regulation of primary metabolic process; GO:0060828 regulation of canonical Wnt signaling pathway; GO:0051353 positive regulation of oxidoreductase activity; GO:0035296 regulation of tube diameter; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0032375 negative regulation of cholesterol transport; GO:0034377 plasma lipoprotein particle assembly; GO:1902532 negative regulation of intracellular signal transduction; GO:0046890 regulation of lipid biosynthetic process; GO:0048844 artery morphogenesis; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0010721 negative regulation of cell development; GO:0060548 negative regulation of cell death; GO:0046503 glycerolipid catabolic process; GO:1901627 negative regulation of postsynaptic membrane organization; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0072359 circulatory system development; GO:0044707 single-multicellular organism process; GO:0030801 positive regulation of cyclic nucleotide metabolic process; GO:0010543 regulation of platelet activation; GO:1902947 regulation of tau-protein kinase activity; GO:0030825 positive regulation of cGMP metabolic process; GO:0009653 anatomical structure morphogenesis; GO:0023057 negative regulation of signaling; GO:1901630 negative regulation of presynaptic membrane organization; GO:0010648 negative regulation of cell communication; GO:0009889 regulation of biosynthetic process; GO:0009896 positive regulation of catabolic process; GO:0031345 negative regulation of cell projection organization; GO:0044248 cellular catabolic process; GO:0051702 interaction with symbiont; GO:0001936 regulation of endothelial cell proliferation; GO:0033700 phospholipid efflux; GO:0035150 regulation of tube size; GO:0048878 chemical homeostasis; GO:0006638 neutral lipid metabolic process; GO:0010872 regulation of cholesterol esterification; GO:0060284 regulation of cell development; GO:0050804 modulation of synaptic transmission; GO:0010977 negative regulation of neuron projection development; GO:0032101 regulation of response to external stimulus; GO:0034381 plasma lipoprotein particle clearance; GO:0015849 organic acid transport; GO:0030195 negative regulation of blood coagulation; GO:0043535 regulation of blood vessel endothelial cell migration; GO:0099536 synaptic signaling; GO:0030826 regulation of cGMP biosynthetic process; GO:0030336 negative regulation of cell migration; GO:0045541 negative regulation of cholesterol biosynthetic process; GO:0007268 chemical synaptic transmission; GO:1903034 regulation of response to wounding; GO:0035023 regulation of Rho protein signal transduction; GO:0050819 negative regulation of coagulation; GO:0051093 negative regulation of developmental process; GO:0015850 organic hydroxy compound transport; GO:0001568 blood vessel development; GO:0030301 cholesterol transport; GO:0017038 protein import; GO:0031331 positive regulation of cellular catabolic process; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0097746 regulation of blood vessel diameter; GO:0040013 negative regulation of locomotion; GO:0007165 signal transduction; GO:0032376 positive regulation of cholesterol transport; GO:0050810 regulation of steroid biosynthetic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:1900046 regulation of hemostasis; GO:0042159 lipoprotein catabolic process; GO:0098916 anterograde trans-synaptic signaling; GO:0033036 macromolecu"}},"GO:0016020 membrane; GO:0030425 dendrite; GO:0005783 endoplasmic reticulum; GO:0044421 extracellular region part; GO:0005615 extracellular space; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0034362 low-density lipoprotein particle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0034358 plasma lipoprotein particle; GO:0044433 cytoplasmic vesicle part; GO:0043025 neuronal cell body; GO:0034385 triglyceride-rich plasma lipoprotein particle; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0034361 very-low-density lipoprotein particle; GO:0044422 organelle part; GO:0005769 early endosome; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0032994 protein-lipid complex; GO:0005622 intracellular; GO:0044464 cell part; GO:1990777 lipoprotein particle; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0005768 endosome; GO:0030139 endocytic vesicle; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0042995 cell projection; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0034363 intermediate-density lipoprotein particle; GO:0034364 high-density lipoprotein particle; GO:0042627 chylomicron; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0031012 extracellular matrix; GO:0043226 organelle; GO:0005634 nucleus; GO:0072562 blood microparticle; GO:0036477 somatodendritic compartment; GO:0060205 cytoplasmic vesicle lumen; GO:0044297 cell body; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0071682 endocytic vesicle lumen; ","GO:0032934 sterol binding; GO:0070326 very-low-density lipoprotein particle receptor binding; GO:0005102 receptor binding; GO:0046983 protein dimerization activity; GO:0005319 lipid transporter activity; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0008201 heparin binding; GO:0098772 molecular function regulator; GO:0005496 steroid binding; GO:0097159 organic cyclic compound binding; GO:0008092 cytoskeletal protein binding; GO:0042802 identical protein binding; GO:0042277 peptide binding; GO:0005488 binding; GO:0008289 lipid binding; GO:0015248 sterol transporter activity; GO:0043169 cation binding; GO:0043168 anion binding; GO:0005539 glycosaminoglycan binding; GO:0008047 enzyme activator activity; GO:0050750 low-density lipoprotein particle receptor binding; GO:0005215 transporter activity; GO:0015485 cholesterol binding; GO:0044877 macromolecular complex binding; GO:0048156 tau protein binding; GO:0043167 ion binding; GO:0016209 antioxidant activity; GO:0071813 lipoprotein particle binding; GO:0033218 amide binding; GO:1901681 sulfur compound binding; GO:0001540 beta-amyloid binding; GO:0070325 lipoprotein particle receptor binding; GO:0097367 carbohydrate derivative binding; GO:0030234 enzyme regulator activity; GO:0017127 cholesterol transporter activity; GO:0042803 protein homodimerization activity; GO:0043178 alcohol binding; GO:0005543 phospholipid binding; GO:0046872 metal ion binding; GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity; GO:0046911 metal chelating activity; GO:0071814 protein-lipid complex binding; GO:0036094 small molecule binding; ","K04524","APOE; apolipoprotein E","hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04979 Cholesterol metabolism - Homo sapiens (human); "]
["P02652","Apolipoprotein A-II OS=Homo sapiens OX=9606 GN=APOA2","APOA2",11.175,26.993,39,4,16,4,0.994,1,1.021,0.979,1.085,0.931,0.993,0.86,"extracellular\r","GO:0044085 cellular component biogenesis; GO:0032371 regulation of sterol transport; GO:0006066 alcohol metabolic process; GO:0009891 positive regulation of biosynthetic process; GO:0002698 negative regulation of immune effector process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0008610 lipid biosynthetic process; GO:0046461 neutral lipid catabolic process; GO:0008152 metabolic process; GO:0065003 macromolecular complex assembly; GO:0050996 positive regulation of lipid catabolic process; GO:0006639 acylglycerol metabolic process; GO:0044093 positive regulation of molecular function; GO:0071825 protein-lipid complex subunit organization; GO:0044057 regulation of system process; GO:0018158 protein oxidation; GO:0051051 negative regulation of transport; GO:0050709 negative regulation of protein secretion; GO:0060621 negative regulation of cholesterol import; GO:0080090 regulation of primary metabolic process; GO:0060191 regulation of lipase activity; GO:0008202 steroid metabolic process; GO:1903531 negative regulation of secretion by cell; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0043086 negative regulation of catalytic activity; GO:0002740 negative regulation of cytokine secretion involved in immune response; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0032375 negative regulation of cholesterol transport; GO:0034377 plasma lipoprotein particle assembly; GO:0002526 acute inflammatory response; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0016101 diterpenoid metabolic process; GO:0051223 regulation of protein transport; GO:0046503 glycerolipid catabolic process; GO:0032677 regulation of interleukin-8 production; GO:0044707 single-multicellular organism process; GO:0002718 regulation of cytokine production involved in immune response; GO:0001819 positive regulation of cytokine production; GO:1901700 response to oxygen-containing compound; GO:0048519 negative regulation of biological process; GO:0042493 response to drug; GO:0009889 regulation of biosynthetic process; GO:2000909 regulation of sterol import; GO:0009896 positive regulation of catabolic process; GO:0034369 plasma lipoprotein particle remodeling; GO:0044248 cellular catabolic process; GO:0033700 phospholipid efflux; GO:0048878 chemical homeostasis; GO:0032409 regulation of transporter activity; GO:0060192 negative regulation of lipase activity; GO:0006638 neutral lipid metabolic process; GO:0006950 response to stress; GO:0044711 single-organism biosynthetic process; GO:0010872 regulation of cholesterol esterification; GO:0010876 lipid localization; GO:0034381 plasma lipoprotein particle clearance; GO:0010033 response to organic substance; GO:1901576 organic substance biosynthetic process; GO:0046340 diacylglycerol catabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0019637 organophosphate metabolic process; GO:0031647 regulation of protein stability; GO:0006644 phospholipid metabolic process; GO:0043412 macromolecule modification; GO:0031100 animal organ regeneration; GO:0046470 phosphatidylcholine metabolic process; GO:0015850 organic hydroxy compound transport; GO:0009746 response to hexose; GO:0046486 glycerolipid metabolic process; GO:0032372 negative regulation of sterol transport; GO:0043627 response to estrogen; GO:0030301 cholesterol transport; GO:0008654 phospholipid biosynthetic process; GO:0044699 single-organism process; GO:0051046 regulation of secretion; GO:0009058 biosynthetic process; GO:0050710 negative regulation of cytokine secretion; GO:0006796 phosphate-containing compound metabolic process; GO:0009395 phospholipid catabolic process; GO:0009893 positive regulation of metabolic process; GO:0050777 negative regulation of immune response; GO:0033036 macromolecule localization; GO:0006629 lipid metabolic process; GO:0045833 negative regulation of lipid metabolic process; GO:0042035 regulation of cytokine biosynthetic process; GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling; GO:0031326 regulation of cellular biosynthetic process; GO:0055114 oxidation-reduction process; GO:0002700 regulation of production of molecular mediator of immune response; GO:1903530 regulation of secretion by cell; GO:0006954 inflammatory response; GO:0046474 glycerophospholipid biosynthetic process; GO:0065009 regulation of molecular function; GO:0065005 protein-lipid complex assembly; GO:0044092 negative regulation of molecular function; GO:0006952 defense response; GO:0036211 protein modification process; GO:0015918 sterol transport; GO:0016043 cellular component organization; GO:1902652 secondary alcohol metabolic process; GO:0046434 organophosphate catabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0032368 regulation of lipid transport; GO:1901566 organonitrogen compound biosynthetic process; GO:0046464 acylglycerol catabolic process; GO:0051346 negative regulation of hydrolase activity; GO:0044058 regulation of digestive system process; GO:0071704 organic substance metabolic process; GO:0097006 regulation of plasma lipoprotein particle levels; GO:0042592 homeostatic process; GO:0033993 response to lipid; GO:0002719 negative regulation of cytokine production involved in immune response; GO:0032757 positive regulation of interleukin-8 production; GO:0016032 viral process; GO:0032410 negative regulation of transporter activity; GO:1904729 regulation of intestinal lipid absorption; GO:0031960 response to corticosteroid; GO:0001523 retinoid metabolic process; GO:0009895 negative regulation of catabolic process; GO:0009059 macromolecule biosynthetic process; GO:2000910 negative regulation of sterol import; GO:0051049 regulation of transport; GO:0050995 negative regulation of lipid catabolic process; GO:0045414 regulation of interleukin-8 biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0043085 positive regulation of catalytic activity; GO:0043933 macromolecular complex subunit organization; GO:0045017 glycerolipid biosynthetic process; GO:0018193 peptidyl-amino acid modification; GO:0034645 cellular macromolecule biosynthetic process; GO:0055092 sterol homeostasis; GO:0001817 regulation of cytokine production; GO:1904950 negative regulation of establishment of protein localization; GO:0031099 regeneration; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065008 regulation of biological quality; GO:0042108 positive regulation of cytokine biosynthetic process; GO:0009749 response to glucose; GO:0019216 regulation of lipid metabolic process; GO:0060694 regulation of cholesterol transporter activity; GO:0042157 lipoprotein metabolic process; GO:0030300 regulation of intestinal cholesterol absorption; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0048545 response to steroid hormone; GO:0009719 response to endogenous stimulus; GO:0009743 response to carbohydrate; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0055088 lipid homeostasis; GO:0044765 single-organism transport; GO:0014070 response to organic cyclic compound; GO:0006869 lipid transport; GO:0009894 regulation of catabolic process; GO:0044281 small molecule metabolic process; GO:0050707 regulation of cytokine secretion; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0002701 negative regulation of production of molecular mediator of immune response; GO:0090407 organophosphate biosynthetic process; GO:0048513 animal organ development; GO:0051336 regulation of hydrolase activity; GO:0034384 high-density lipoprotein particle clearance; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0034284 response to monosaccharide; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0002682 regulation of immune system process; GO:0050994 regulation of lipid catabolic process; GO:0046339 diacylglycerol metabolic process; GO:0045416 positive regulation of interleukin-8 biosynthetic process; GO:0010873 positive regulation of cholesterol esterification; GO:0018206 peptidyl-methionine modification; GO:0050794 regulation of cellular process; GO:0060620 regulation of cholesterol import; GO:1901615 organic hydroxy compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0097164 ammonium ion metabolic process; GO:0019218 regulation of steroid metabolic process; GO:0048523 negative regulation of cellular process; GO:0045940 positive regulation of steroid metabolic process; GO:0016125 sterol metabolic process; GO:0051239 regulation of multicellular organismal process; GO:0034370 triglyceride-rich lipoprotein particle remodeling; GO:1902578 single-organism localization; GO:0007275 multicellular organism development; GO:0032880 regulation of protein localization; GO:0016042 lipid catabolic process; GO:0006720 isoprenoid metabolic process; GO:0008203 cholesterol metabolic process; GO:0051224 negative regulation of protein transport; GO:0048731 system development; GO:0071702 organic substance transport; GO:0015914 phospholipid transport; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0051247 positive regulation of protein metabolic process; GO:0006641 triglyceride metabolic process; GO:0006793 phosphorus metabolic process; GO:0006811 ion transport; GO:0044242 cellular lipid catabolic process; GO:0034375 high-density lipoprotein particle remodeling; GO:0051179 localization; GO:0031328 positive regulation of cellular biosynthetic process; GO:0010901 regulation of very-low-density lipoprotein particle remodeling; GO:1901564 organonitrogen compound metabolic process; GO:0034367 macromolecular complex remodeling; GO:0033344 cholesterol efflux; GO:0051129 negative regulation of cellular component organization; GO:0051241 negative regulation of multicellular organismal process; GO:1904478 regulation of intestinal absorption; GO:0044764 multi-organism cellular process; GO:0001818 negative regulation of cytokine production; GO:0051234 establishment of localization; GO:0022607 cellular component assembly; GO:0006650 glycerophospholipid metabolic process; GO:0042158 lipoprotein biosynthetic process; GO:0043691 reverse cholesterol transport; GO:0002697 regulation of immune effector process; GO:0006656 phosphatidylcholine biosynthetic process; GO:0032502 developmental process; GO:0071827 plasma lipoprotein particle organization; GO:0032369 negative regulation of lipid transport; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0032374 regulation of cholesterol transport; GO:0051384 response to glucocorticoid; GO:0002683 negative regulation of immune system process; GO:0015748 organophosphate ester transport; GO:0051048 negative regulation of secretion; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0019222 regulation of metabolic process; GO:0048856 anatomical structure development; GO:0034374 low-density lipoprotein particle remodeling; GO:0060695 negative regulation of cholesterol transporter activity; GO:0050896 response to stimulus; GO:0070201 regulation of establishment of protein localization; GO:0050708 regulation of protein secretion; GO:0002739 regulation of cytokine secretion involved in immune response; GO:0009987 cellular process; GO:0044712 single-organism catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0042632 cholesterol homeostasis; GO:0048518 positive regulation of biological process; GO:0045834 positive regulation of lipid metabolic process; GO:0006820 anion transport; GO:0015711 organic anion transport; GO:0034380 high-density lipoprotein particle assembly; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0006721 terpenoid metabolic process; GO:0051128 regulation of cellular component organization; GO:0009725 response to hormone; GO:0034368 protein-lipid complex remodeling; GO:0065007 biological regulation; ","GO:0005783 endoplasmic reticulum; GO:0044421 extracellular region part; GO:0005615 extracellular space; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0034358 plasma lipoprotein particle; GO:0034385 triglyceride-rich plasma lipoprotein particle; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0034361 very-low-density lipoprotein particle; GO:0044422 organelle part; GO:0005769 early endosome; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0070013 intracellular organelle lumen; GO:0032994 protein-lipid complex; GO:0005622 intracellular; GO:0044464 cell part; GO:1990777 lipoprotein particle; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0005788 endoplasmic reticulum lumen; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0042627 chylomicron; GO:0034364 high-density lipoprotein particle; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0072562 blood microparticle; GO:0044432 endoplasmic reticulum part; GO:0034366 spherical high-density lipoprotein particle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0032934 sterol binding; GO:0070405 ammonium ion binding; GO:0005102 receptor binding; GO:0046983 protein dimerization activity; GO:0005319 lipid transporter activity; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0005496 steroid binding; GO:0097159 organic cyclic compound binding; GO:0031210 phosphatidylcholine binding; GO:0050997 quaternary ammonium group binding; GO:0042802 identical protein binding; GO:0008035 high-density lipoprotein particle binding; GO:0005488 binding; GO:0015248 sterol transporter activity; GO:0008289 lipid binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0008047 enzyme activator activity; GO:0005215 transporter activity; GO:0055102 lipase inhibitor activity; GO:0015485 cholesterol binding; GO:0070653 high-density lipoprotein particle receptor binding; GO:0046982 protein heterodimerization activity; GO:0034190 apolipoprotein receptor binding; GO:0043167 ion binding; GO:0044877 macromolecular complex binding; GO:0071813 lipoprotein particle binding; GO:0070325 lipoprotein particle receptor binding; GO:0030234 enzyme regulator activity; GO:0017127 cholesterol transporter activity; GO:0043178 alcohol binding; GO:0042803 protein homodimerization activity; GO:0005543 phospholipid binding; GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity; GO:0071814 protein-lipid complex binding; GO:0036094 small molecule binding; ","K08758","APOA2; apolipoprotein A-II","hsa03320 PPAR signaling pathway - Homo sapiens (human); hsa04979 Cholesterol metabolism - Homo sapiens (human); "]
["P02654","Apolipoprotein C-I OS=Homo sapiens OX=9606 GN=APOC1","APOC1",9.3318,20.805,37.3,6,17,6,0.94,0.914,0.948,1.068,1.076,1.093,1.155,0.000375,"extracellular\r","GO:0060627 regulation of vesicle-mediated transport; GO:0044085 cellular component biogenesis; GO:0032371 regulation of sterol transport; GO:0006066 alcohol metabolic process; GO:0034379 very-low-density lipoprotein particle assembly; GO:0044255 cellular lipid metabolic process; GO:0019216 regulation of lipid metabolic process; GO:0044237 cellular metabolic process; GO:0042157 lipoprotein metabolic process; GO:0008152 metabolic process; GO:0032879 regulation of localization; GO:0065003 macromolecular complex assembly; GO:0006639 acylglycerol metabolic process; GO:0044093 positive regulation of molecular function; GO:0071825 protein-lipid complex subunit organization; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0044765 single-organism transport; GO:0051051 negative regulation of transport; GO:0051174 regulation of phosphorus metabolic process; GO:0010985 negative regulation of lipoprotein particle clearance; GO:0006869 lipid transport; GO:0048259 regulation of receptor-mediated endocytosis; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0044281 small molecule metabolic process; GO:0009894 regulation of catabolic process; GO:0060696 regulation of phospholipid catabolic process; GO:0060191 regulation of lipase activity; GO:0008202 steroid metabolic process; GO:0044763 single-organism cellular process; GO:0031323 regulation of cellular metabolic process; GO:0043086 negative regulation of catalytic activity; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:0032375 negative regulation of cholesterol transport; GO:0048261 negative regulation of receptor-mediated endocytosis; GO:0034377 plasma lipoprotein particle assembly; GO:0051336 regulation of hydrolase activity; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0046890 regulation of lipid biosynthetic process; GO:0042304 regulation of fatty acid biosynthetic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0050994 regulation of lipid catabolic process; GO:0010873 positive regulation of cholesterol esterification; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:1901615 organic hydroxy compound metabolic process; GO:1903725 regulation of phospholipid metabolic process; GO:0019218 regulation of steroid metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0045940 positive regulation of steroid metabolic process; GO:0016125 sterol metabolic process; GO:0051239 regulation of multicellular organismal process; GO:0045806 negative regulation of endocytosis; GO:1902578 single-organism localization; GO:0009889 regulation of biosynthetic process; GO:0051004 regulation of lipoprotein lipase activity; GO:0034369 plasma lipoprotein particle remodeling; GO:0051171 regulation of nitrogen compound metabolic process; GO:0033700 phospholipid efflux; GO:0060192 negative regulation of lipase activity; GO:0006638 neutral lipid metabolic process; GO:0008203 cholesterol metabolic process; GO:0030100 regulation of endocytosis; GO:0010872 regulation of cholesterol esterification; GO:0071702 organic substance transport; GO:0010876 lipid localization; GO:0015914 phospholipid transport; GO:0034381 plasma lipoprotein particle clearance; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0019217 regulation of fatty acid metabolic process; GO:0031330 negative regulation of cellular catabolic process; GO:0009890 negative regulation of biosynthetic process; GO:0006641 triglyceride metabolic process; GO:0006811 ion transport; GO:0031325 positive regulation of cellular metabolic process; GO:0045717 negative regulation of fatty acid biosynthetic process; GO:0034375 high-density lipoprotein particle remodeling; GO:0051179 localization; GO:0045936 negative regulation of phosphate metabolic process; GO:0034367 macromolecular complex remodeling; GO:0015850 organic hydroxy compound transport; GO:0032372 negative regulation of sterol transport; GO:0046486 glycerolipid metabolic process; GO:0030301 cholesterol transport; GO:0033344 cholesterol efflux; GO:0051129 negative regulation of cellular component organization; GO:0044699 single-organism process; GO:0051241 negative regulation of multicellular organismal process; GO:0051234 establishment of localization; GO:0010900 negative regulation of phosphatidylcholine catabolic process; GO:0009893 positive regulation of metabolic process; GO:0022607 cellular component assembly; GO:0045922 negative regulation of fatty acid metabolic process; GO:0033036 macromolecule localization; GO:0006629 lipid metabolic process; GO:0010915 regulation of very-low-density lipoprotein particle clearance; GO:0071827 plasma lipoprotein particle organization; GO:0051055 negative regulation of lipid biosynthetic process; GO:0045833 negative regulation of lipid metabolic process; GO:0031326 regulation of cellular biosynthetic process; GO:0032369 negative regulation of lipid transport; GO:0010899 regulation of phosphatidylcholine catabolic process; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0032374 regulation of cholesterol transport; GO:0010565 regulation of cellular ketone metabolic process; GO:0015748 organophosphate ester transport; GO:0050789 regulation of biological process; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0065005 protein-lipid complex assembly; GO:0019220 regulation of phosphate metabolic process; GO:0015918 sterol transport; GO:0016043 cellular component organization; GO:0051005 negative regulation of lipoprotein lipase activity; GO:1902652 secondary alcohol metabolic process; GO:0032368 regulation of lipid transport; GO:0031324 negative regulation of cellular metabolic process; GO:0034382 chylomicron remnant clearance; GO:0051346 negative regulation of hydrolase activity; GO:0071704 organic substance metabolic process; GO:0097006 regulation of plasma lipoprotein particle levels; GO:1903726 negative regulation of phospholipid metabolic process; GO:0009895 negative regulation of catabolic process; GO:0010984 regulation of lipoprotein particle clearance; GO:0009987 cellular process; GO:0010916 negative regulation of very-low-density lipoprotein particle clearance; GO:0051049 regulation of transport; GO:0050995 negative regulation of lipid catabolic process; GO:0048518 positive regulation of biological process; GO:0045834 positive regulation of lipid metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0043085 positive regulation of catalytic activity; GO:0006820 anion transport; GO:0015711 organic anion transport; GO:0010563 negative regulation of phosphorus metabolic process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0051128 regulation of cellular component organization; GO:0034447 very-low-density lipoprotein particle clearance; GO:0034368 protein-lipid complex remodeling; GO:0071830 triglyceride-rich lipoprotein particle clearance; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0005615 extracellular space; GO:0005783 endoplasmic reticulum; GO:0031982 vesicle; GO:0034358 plasma lipoprotein particle; GO:0005737 cytoplasm; GO:0034385 triglyceride-rich plasma lipoprotein particle; GO:0032991 macromolecular complex; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0042627 chylomicron; GO:0034364 high-density lipoprotein particle; GO:0005623 cell; GO:0005576 extracellular region; GO:0034361 very-low-density lipoprotein particle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0032994 protein-lipid complex; GO:0005622 intracellular; GO:0044464 cell part; GO:1990777 lipoprotein particle; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0070405 ammonium ion binding; GO:0055102 lipase inhibitor activity; GO:0043167 ion binding; GO:0043177 organic acid binding; GO:0004859 phospholipase inhibitor activity; GO:0033293 monocarboxylic acid binding; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0031210 phosphatidylcholine binding; GO:0050997 quaternary ammonium group binding; GO:0031406 carboxylic acid binding; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0005543 phospholipid binding; GO:0008289 lipid binding; GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity; GO:0043169 cation binding; GO:0043168 anion binding; GO:0005504 fatty acid binding; GO:0008047 enzyme activator activity; GO:0036094 small molecule binding; "]
["P02655","Apolipoprotein C-II OS=Homo sapiens OX=9606 GN=APOC2","APOC2",11.284,46.82,49.5,4,6,4,0.932,0.908,0.979,1.029,1.121,1.044,1.133,0.0224,"extracellular\r","GO:0060627 regulation of vesicle-mediated transport; GO:0065008 regulation of biological quality; GO:0032371 regulation of sterol transport; GO:0009891 positive regulation of biosynthetic process; GO:0044255 cellular lipid metabolic process; GO:0070328 triglyceride homeostasis; GO:0019216 regulation of lipid metabolic process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0042157 lipoprotein metabolic process; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0050996 positive regulation of lipid catabolic process; GO:0044093 positive regulation of molecular function; GO:0071825 protein-lipid complex subunit organization; GO:0010562 positive regulation of phosphorus metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0008104 protein localization; GO:0055088 lipid homeostasis; GO:0046889 positive regulation of lipid biosynthetic process; GO:0044765 single-organism transport; GO:0051051 negative regulation of transport; GO:0051174 regulation of phosphorus metabolic process; GO:0010985 negative regulation of lipoprotein particle clearance; GO:0006869 lipid transport; GO:0048259 regulation of receptor-mediated endocytosis; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0060191 regulation of lipase activity; GO:0009894 regulation of catabolic process; GO:0060696 regulation of phospholipid catabolic process; GO:0044763 single-organism cellular process; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0032375 negative regulation of cholesterol transport; GO:0048261 negative regulation of receptor-mediated endocytosis; GO:0051336 regulation of hydrolase activity; GO:0034384 high-density lipoprotein particle clearance; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0046890 regulation of lipid biosynthetic process; GO:0042304 regulation of fatty acid biosynthetic process; GO:0090208 positive regulation of triglyceride metabolic process; GO:0016101 diterpenoid metabolic process; GO:0050994 regulation of lipid catabolic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0010896 regulation of triglyceride catabolic process; GO:1903725 regulation of phospholipid metabolic process; GO:0034372 very-low-density lipoprotein particle remodeling; GO:0010517 regulation of phospholipase activity; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0051239 regulation of multicellular organismal process; GO:0042493 response to drug; GO:0034370 triglyceride-rich lipoprotein particle remodeling; GO:0060697 positive regulation of phospholipid catabolic process; GO:0045806 negative regulation of endocytosis; GO:1902578 single-organism localization; GO:0051345 positive regulation of hydrolase activity; GO:0009889 regulation of biosynthetic process; GO:0061365 positive regulation of triglyceride lipase activity; GO:0051004 regulation of lipoprotein lipase activity; GO:0009896 positive regulation of catabolic process; GO:0034369 plasma lipoprotein particle remodeling; GO:0010518 positive regulation of phospholipase activity; GO:0090207 regulation of triglyceride metabolic process; GO:0033700 phospholipid efflux; GO:0051006 positive regulation of lipoprotein lipase activity; GO:0048878 chemical homeostasis; GO:0016042 lipid catabolic process; GO:0010898 positive regulation of triglyceride catabolic process; GO:0006720 isoprenoid metabolic process; GO:0030100 regulation of endocytosis; GO:0071702 organic substance transport; GO:0010876 lipid localization; GO:0015914 phospholipid transport; GO:0034381 plasma lipoprotein particle clearance; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0019217 regulation of fatty acid metabolic process; GO:0045184 establishment of protein localization; GO:0006811 ion transport; GO:0031325 positive regulation of cellular metabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0051179 localization; GO:1903727 positive regulation of phospholipid metabolic process; GO:0045923 positive regulation of fatty acid metabolic process; GO:0010901 regulation of very-low-density lipoprotein particle remodeling; GO:0034367 macromolecular complex remodeling; GO:0015850 organic hydroxy compound transport; GO:0032372 negative regulation of sterol transport; GO:0030301 cholesterol transport; GO:0033344 cholesterol efflux; GO:0051129 negative regulation of cellular component organization; GO:0031331 positive regulation of cellular catabolic process; GO:0044699 single-organism process; GO:0051241 negative regulation of multicellular organismal process; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0044872 lipoprotein localization; GO:0009893 positive regulation of metabolic process; GO:0033036 macromolecule localization; GO:0043691 reverse cholesterol transport; GO:0006629 lipid metabolic process; GO:0010915 regulation of very-low-density lipoprotein particle clearance; GO:0071827 plasma lipoprotein particle organization; GO:0045833 negative regulation of lipid metabolic process; GO:0045937 positive regulation of phosphate metabolic process; GO:0031326 regulation of cellular biosynthetic process; GO:0032369 negative regulation of lipid transport; GO:0048522 positive regulation of cellular process; GO:0032374 regulation of cholesterol transport; GO:0010565 regulation of cellular ketone metabolic process; GO:0060193 positive regulation of lipase activity; GO:0015748 organophosphate ester transport; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0045723 positive regulation of fatty acid biosynthetic process; GO:0044092 negative regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0015918 sterol transport; GO:0016043 cellular component organization; GO:0032368 regulation of lipid transport; GO:0050896 response to stimulus; GO:0034382 chylomicron remnant clearance; GO:0071704 organic substance metabolic process; GO:0097006 regulation of plasma lipoprotein particle levels; GO:0042592 homeostatic process; GO:0001523 retinoid metabolic process; GO:0010984 regulation of lipoprotein particle clearance; GO:0009987 cellular process; GO:0034371 chylomicron remodeling; GO:0010916 negative regulation of very-low-density lipoprotein particle clearance; GO:0051049 regulation of transport; GO:0044712 single-organism catabolic process; GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling; GO:0042632 cholesterol homeostasis; GO:0042953 lipoprotein transport; GO:0048518 positive regulation of biological process; GO:0045834 positive regulation of lipid metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0043085 positive regulation of catalytic activity; GO:0006820 anion transport; GO:0015711 organic anion transport; GO:0055090 acylglycerol homeostasis; GO:0055092 sterol homeostasis; GO:0006721 terpenoid metabolic process; GO:0051128 regulation of cellular component organization; GO:0034368 protein-lipid complex remodeling; GO:0009056 catabolic process; GO:0071830 triglyceride-rich lipoprotein particle clearance; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0034362 low-density lipoprotein particle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0034358 plasma lipoprotein particle; GO:0034385 triglyceride-rich plasma lipoprotein particle; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0034361 very-low-density lipoprotein particle; GO:0005769 early endosome; GO:0070062 extracellular exosome; GO:0032994 protein-lipid complex; GO:0005622 intracellular; GO:0044464 cell part; GO:1990777 lipoprotein particle; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0012505 endomembrane system; GO:0034363 intermediate-density lipoprotein particle; GO:0034364 high-density lipoprotein particle; GO:0042627 chylomicron; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0034366 spherical high-density lipoprotein particle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0055102 lipase inhibitor activity; GO:0043274 phospholipase binding; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:0004857 enzyme inhibitor activity; GO:0016004 phospholipase activator activity; GO:0098772 molecular function regulator; GO:0042802 identical protein binding; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0042803 protein homodimerization activity; GO:0060229 lipase activator activity; GO:0008289 lipid binding; GO:0060230 lipoprotein lipase activator activity; GO:0019899 enzyme binding; GO:0008047 enzyme activator activity; ",{"$nulls":3},"IPR023121; ","ApoC-II domain; \r"]
["P02656","Apolipoprotein C-III OS=Homo sapiens OX=9606 GN=APOC3","APOC3",10.852,69.375,53.5,4,11,4,0.966,0.916,0.919,1.047,1.108,1.091,1.159,3.62E-3,"extracellular\r","GO:0060627 regulation of vesicle-mediated transport; GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0032371 regulation of sterol transport; GO:0034379 very-low-density lipoprotein particle assembly; GO:0044255 cellular lipid metabolic process; GO:0070328 triglyceride homeostasis; GO:0019216 regulation of lipid metabolic process; GO:0044237 cellular metabolic process; GO:0042157 lipoprotein metabolic process; GO:0046461 neutral lipid catabolic process; GO:0008152 metabolic process; GO:0032879 regulation of localization; GO:0065003 macromolecular complex assembly; GO:0006639 acylglycerol metabolic process; GO:0071825 protein-lipid complex subunit organization; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0032489 regulation of Cdc42 protein signal transduction; GO:0055088 lipid homeostasis; GO:0051056 regulation of small GTPase mediated signal transduction; GO:0044765 single-organism transport; GO:0051051 negative regulation of transport; GO:0051716 cellular response to stimulus; GO:0010985 negative regulation of lipoprotein particle clearance; GO:0006869 lipid transport; GO:0048259 regulation of receptor-mediated endocytosis; GO:0060621 negative regulation of cholesterol import; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0010988 regulation of low-density lipoprotein particle clearance; GO:0060191 regulation of lipase activity; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0032375 negative regulation of cholesterol transport; GO:0048261 negative regulation of receptor-mediated endocytosis; GO:0034377 plasma lipoprotein particle assembly; GO:0051336 regulation of hydrolase activity; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0046890 regulation of lipid biosynthetic process; GO:0048583 regulation of response to stimulus; GO:0042304 regulation of fatty acid biosynthetic process; GO:0016101 diterpenoid metabolic process; GO:0050994 regulation of lipid catabolic process; GO:0046503 glycerolipid catabolic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0060620 regulation of cholesterol import; GO:0010896 regulation of triglyceride catabolic process; GO:0010897 negative regulation of triglyceride catabolic process; GO:0010982 regulation of high-density lipoprotein particle clearance; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0051239 regulation of multicellular organismal process; GO:0045806 negative regulation of endocytosis; GO:1902578 single-organism localization; GO:0009889 regulation of biosynthetic process; GO:2000909 regulation of sterol import; GO:0051004 regulation of lipoprotein lipase activity; GO:0034369 plasma lipoprotein particle remodeling; GO:0044248 cellular catabolic process; GO:0033700 phospholipid efflux; GO:0090207 regulation of triglyceride metabolic process; GO:0009966 regulation of signal transduction; GO:0048878 chemical homeostasis; GO:0060192 negative regulation of lipase activity; GO:0006638 neutral lipid metabolic process; GO:0016042 lipid catabolic process; GO:0006720 isoprenoid metabolic process; GO:0030100 regulation of endocytosis; GO:1902531 regulation of intracellular signal transduction; GO:0010876 lipid localization; GO:0071702 organic substance transport; GO:0015914 phospholipid transport; GO:0034381 plasma lipoprotein particle clearance; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0019217 regulation of fatty acid metabolic process; GO:0007186 G-protein coupled receptor signaling pathway; GO:0031330 negative regulation of cellular catabolic process; GO:0009890 negative regulation of biosynthetic process; GO:0006641 triglyceride metabolic process; GO:0006811 ion transport; GO:0044242 cellular lipid catabolic process; GO:0034375 high-density lipoprotein particle remodeling; GO:0045717 negative regulation of fatty acid biosynthetic process; GO:0051179 localization; GO:0035023 regulation of Rho protein signal transduction; GO:0010901 regulation of very-low-density lipoprotein particle remodeling; GO:0034367 macromolecular complex remodeling; GO:0015850 organic hydroxy compound transport; GO:0032372 negative regulation of sterol transport; GO:0046486 glycerolipid metabolic process; GO:0030301 cholesterol transport; GO:0033344 cholesterol efflux; GO:0023051 regulation of signaling; GO:0051129 negative regulation of cellular component organization; GO:0044699 single-organism process; GO:0051241 negative regulation of multicellular organismal process; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0045922 negative regulation of fatty acid metabolic process; GO:0033036 macromolecule localization; GO:0043691 reverse cholesterol transport; GO:0006629 lipid metabolic process; GO:0010915 regulation of very-low-density lipoprotein particle clearance; GO:0071827 plasma lipoprotein particle organization; GO:0051055 negative regulation of lipid biosynthetic process; GO:0045833 negative regulation of lipid metabolic process; GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling; GO:0031326 regulation of cellular biosynthetic process; GO:0032369 negative regulation of lipid transport; GO:0023052 signaling; GO:0032374 regulation of cholesterol transport; GO:0010565 regulation of cellular ketone metabolic process; GO:0010989 negative regulation of low-density lipoprotein particle clearance; GO:0015748 organophosphate ester transport; GO:0050789 regulation of biological process; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0010987 negative regulation of high-density lipoprotein particle clearance; GO:0044092 negative regulation of molecular function; GO:0065005 protein-lipid complex assembly; GO:0015918 sterol transport; GO:0016043 cellular component organization; GO:0051005 negative regulation of lipoprotein lipase activity; GO:0032368 regulation of lipid transport; GO:0046578 regulation of Ras protein signal transduction; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0034382 chylomicron remnant clearance; GO:0051346 negative regulation of hydrolase activity; GO:0046464 acylglycerol catabolic process; GO:0071704 organic substance metabolic process; GO:0097006 regulation of plasma lipoprotein particle levels; GO:0042592 homeostatic process; GO:0001523 retinoid metabolic process; GO:0009895 negative regulation of catabolic process; GO:0010984 regulation of lipoprotein particle clearance; GO:0009987 cellular process; GO:0019433 triglyceride catabolic process; GO:0010916 negative regulation of very-low-density lipoprotein particle clearance; GO:2000910 negative regulation of sterol import; GO:0051049 regulation of transport; GO:0044712 single-organism catabolic process; GO:0050995 negative regulation of lipid catabolic process; GO:0042632 cholesterol homeostasis; GO:0043933 macromolecular complex subunit organization; GO:0006820 anion transport; GO:0015711 organic anion transport; GO:0055090 acylglycerol homeostasis; GO:0055092 sterol homeostasis; GO:0006721 terpenoid metabolic process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0090209 negative regulation of triglyceride metabolic process; GO:0051128 regulation of cellular component organization; GO:0034368 protein-lipid complex remodeling; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:0071830 triglyceride-rich lipoprotein particle clearance; ","GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0034358 plasma lipoprotein particle; GO:0034385 triglyceride-rich plasma lipoprotein particle; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0034361 very-low-density lipoprotein particle; GO:0005769 early endosome; GO:0070062 extracellular exosome; GO:0032994 protein-lipid complex; GO:0005622 intracellular; GO:0044464 cell part; GO:1990777 lipoprotein particle; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0012505 endomembrane system; GO:0034363 intermediate-density lipoprotein particle; GO:0042627 chylomicron; GO:0034364 high-density lipoprotein particle; GO:0005576 extracellular region; GO:0043226 organelle; GO:0034366 spherical high-density lipoprotein particle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0015485 cholesterol binding; GO:0032934 sterol binding; GO:0055102 lipase inhibitor activity; GO:0070653 high-density lipoprotein particle receptor binding; GO:0005102 receptor binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0004857 enzyme inhibitor activity; GO:0005496 steroid binding; GO:0097159 organic cyclic compound binding; GO:0070325 lipoprotein particle receptor binding; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0043178 alcohol binding; GO:0005543 phospholipid binding; GO:0008289 lipid binding; GO:0043168 anion binding; GO:0036094 small molecule binding; ","K08759","APOC3; apolipoprotein C-III","hsa03320 PPAR signaling pathway - Homo sapiens (human); hsa04979 Cholesterol metabolism - Homo sapiens (human); "]
["P02671","Fibrinogen alpha chain OS=Homo sapiens OX=9606 GN=FGA","FGA",94.972,323.31,49.9,42,116,42,0.913,0.875,0.872,1.118,1.138,1.091,1.258,0.000279,"extracellular\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0072377 blood coagulation, common pathway; GO:0098542 defense response to other organism; GO:0002793 positive regulation of peptide secretion; GO:0031347 regulation of defense response; GO:0043152 induction of bacterial agglutination; GO:0044237 cellular metabolic process; GO:0009607 response to biotic stimulus; GO:0042730 fibrinolysis; GO:0008152 metabolic process; GO:0065003 macromolecular complex assembly; GO:0007160 cell-matrix adhesion; GO:0044057 regulation of system process; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0019229 regulation of vasoconstriction; GO:0080090 regulation of primary metabolic process; GO:0030168 platelet activation; GO:1900026 positive regulation of substrate adhesion-dependent cell spreading; GO:0044763 single-organism cellular process; GO:0035296 regulation of tube diameter; GO:0010811 positive regulation of cell-substrate adhesion; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0006810 transport; GO:0048583 regulation of response to stimulus; GO:0098602 single organism cell adhesion; GO:0044260 cellular macromolecule metabolic process; GO:0051223 regulation of protein transport; GO:0060548 negative regulation of cell death; GO:0044707 single-multicellular organism process; GO:2000257 regulation of protein activation cascade; GO:0050880 regulation of blood vessel size; GO:0017157 regulation of exocytosis; GO:0002576 platelet degranulation; GO:0003018 vascular process in circulatory system; GO:0048519 negative regulation of biological process; GO:0090277 positive regulation of peptide hormone secretion; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0043062 extracellular structure organization; GO:0035150 regulation of tube size; GO:0050778 positive regulation of immune response; GO:0045785 positive regulation of cell adhesion; GO:0006950 response to stress; GO:0060284 regulation of cell development; GO:0032101 regulation of response to external stimulus; GO:0002376 immune system process; GO:0072378 blood coagulation, fibrin clot formation; GO:0030195 negative regulation of blood coagulation; GO:0045055 regulated exocytosis; GO:0061041 regulation of wound healing; GO:0031325 positive regulation of cellular metabolic process; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:0006955 immune response; GO:1903034 regulation of response to wounding; GO:0050819 negative regulation of coagulation; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0051046 regulation of secretion; GO:0016485 protein processing; GO:0097746 regulation of blood vessel diameter; GO:0009611 response to wounding; GO:0016337 single organismal cell-cell adhesion; GO:0007165 signal transduction; GO:0009893 positive regulation of metabolic process; GO:0031639 plasminogen activation; GO:1900046 regulation of hemostasis; GO:0002221 pattern recognition receptor signaling pathway; GO:0030198 extracellular matrix organization; GO:0019731 antibacterial humoral response; GO:0045937 positive regulation of phosphate metabolic process; GO:0098609 cell-cell adhesion; GO:0002764 immune response-regulating signaling pathway; GO:1903530 regulation of secretion by cell; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0010038 response to metal ion; GO:1903035 negative regulation of response to wounding; GO:0032940 secretion by cell; GO:2001236 regulation of extrinsic apoptotic signaling pathway; GO:0006952 defense response; GO:0070271 protein complex biogenesis; GO:0051222 positive regulation of protein transport; GO:0016043 cellular component organization; GO:0043069 negative regulation of programmed cell death; GO:0060255 regulation of macromolecule metabolic process; GO:1903522 regulation of blood circulation; GO:0010770 positive regulation of cell morphogenesis involved in differentiation; GO:0051707 response to other organism; GO:0045087 innate immune response; GO:0071704 organic substance metabolic process; GO:0034116 positive regulation of heterotypic cell-cell adhesion; GO:0043408 regulation of MAPK cascade; GO:0043066 negative regulation of apoptotic process; GO:0023056 positive regulation of signaling; GO:0008015 blood circulation; GO:0002757 immune response-activating signal transduction; GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors; GO:0051592 response to calcium ion; GO:0010647 positive regulation of cell communication; GO:0045595 regulation of cell differentiation; GO:0043623 cellular protein complex assembly; GO:0034622 cellular macromolecular complex assembly; GO:0050878 regulation of body fluid levels; GO:0042742 defense response to bacterium; GO:0051049 regulation of transport; GO:0001932 regulation of protein phosphorylation; GO:0045907 positive regulation of vasoconstriction; GO:0001934 positive regulation of protein phosphorylation; GO:0022407 regulation of cell-cell adhesion; GO:0043933 macromolecular complex subunit organization; GO:2000261 negative regulation of blood coagulation, common pathway; GO:0002684 positive regulation of immune system process; GO:0051248 negative regulation of protein metabolic process; GO:0010467 gene expression; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0060627 regulation of vesicle-mediated transport; GO:0065008 regulation of biological quality; GO:0007596 blood coagulation; GO:2000351 regulation of endothelial cell apoptotic process; GO:0032270 positive regulation of cellular protein metabolic process; GO:1904036 negative regulation of epithelial cell apoptotic process; GO:0009605 response to external stimulus; GO:0022610 biological adhesion; GO:2000260 regulation of blood coagulation, common pathway; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0032102 negative regulation of response to external stimulus; GO:0007155 cell adhesion; GO:0010562 positive regulation of phosphorus metabolic process; GO:0042327 positive regulation of phosphorylation; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0031638 zymogen activation; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0051174 regulation of phosphorus metabolic process; GO:0045921 positive regulation of exocytosis; GO:0002758 innate immune response-activating signal transduction; GO:0019730 antimicrobial humoral response; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0046883 regulation of hormone secretion; GO:0050714 positive regulation of protein secretion; GO:0010817 regulation of hormone levels; GO:0010604 positive regulation of macromolecule metabolic process; GO:0002682 regulation of immune system process; GO:0050817 coagulation; GO:0003013 circulatory system process; GO:0051094 positive regulation of developmental process; GO:0051047 positive regulation of secretion; GO:0050794 regulation of cellular process; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0030193 regulation of blood coagulation; GO:0043067 regulation of programmed cell death; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0034109 homotypic cell-cell adhesion; GO:0051239 regulation of multicellular organismal process; GO:0045597 positive regulation of cell differentiation; GO:1900047 negative regulation of hemostasis; GO:2000258 negative regulation of protein activation cascade; GO:0031349 positive regulation of defense response; GO:0070372 regulation of ERK1 and ERK2 cascade; GO:1902578 single-organism localization; GO:1900024 regulation of substrate adhesion-dependent cell spreading; GO:0032880 regulation of protein localization; GO:0009966 regulation of signal transduction; GO:0009617 response to bacterium; GO:0006461 protein complex assembly; GO:1904035 regulation of epithelial cell apoptotic process; GO:0090087 regulation of peptide transport; GO:0002253 activation of immune response; GO:1902531 regulation of intracellular signal transduction; GO:0016192 vesicle-mediated transport; GO:0072376 protein activation cascade; GO:2001237 negative regulation of extrinsic apoptotic signaling pathway; GO:0044238 primary metabolic process; GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; GO:0009892 negative regulation of metabolic process; GO:0030155 regulation of cell adhesion; GO:0051247 positive regulation of protein metabolic process; GO:1904951 positive regulation of establishment of protein localization; GO:0046887 positive regulation of hormone secretion; GO:0001775 cell activation; GO:0051179 localization; GO:0010810 regulation of cell-substrate adhesion; GO:0048584 positive regulation of response to stimulus; GO:0050793 regulation of developmental process; GO:0006887 exocytosis; GO:1902533 positive regulation of intracellular signal transduction; GO:0051241 negative regulation of multicellular organismal process; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:2001233 regulation of apoptotic signaling pathway; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0045088 regulation of innate immune response; GO:2000352 negative regulation of endothelial cell apoptotic process; GO:0002250 adaptive immune response; GO:0010035 response to inorganic substance; GO:0010720 positive regulation of cell development; GO:0071822 protein complex subunit organization; GO:0048522 positive regulation of cellular process; GO:0051050 positive regulation of transport; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0034114 regulation of heterotypic cell-cell adhesion; GO:1903532 positive regulation of secretion by cell; GO:0002224 toll-like receptor signaling pathway; GO:0051258 protein polymerization; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0070527 platelet aggregation; GO:0002218 activation of innate immune response; GO:0006959 humoral immune response; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0007599 hemostasis; GO:0070201 regulation of establishment of protein localization; GO:0002791 regulation of peptide secretion; GO:0006508 proteolysis; GO:1903524 positive regulation of blood circulation; GO:0050708 regulation of protein secretion; GO:0009987 cellular process; GO:0003008 system process; GO:0045089 positive regulation of innate immune response; GO:0022409 positive regulation of cell-cell adhesion; GO:0031401 positive regulation of protein modification process; GO:0048585 negative regulation of response to stimulus; GO:0061045 negative regulation of wound healing; GO:0048518 positive regulation of biological process; GO:0050818 regulation of coagulation; GO:0042060 wound healing; GO:0031589 cell-substrate adhesion; GO:0051246 regulation of protein metabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0090276 regulation of peptide hormone secretion; GO:0090066 regulation of anatomical structure size; GO:0051128 regulation of cellular component organization; GO:0009967 positive regulation of signal transduction; GO:0051604 protein maturation; GO:0043410 positive regulation of MAPK cascade; GO:0022604 regulation of cell morphogenesis; GO:0070374 positive regulation of ERK1 and ERK2 cascade; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005938 cell cortex; GO:0009897 external side of plasma membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0099568 cytoplasmic region; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0098552 side of membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0005577 fibrinogen complex; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0072562 blood microparticle; GO:0060205 cytoplasmic vesicle lumen; GO:0044459 plasma membrane part; GO:0031093 platelet alpha granule lumen; GO:0009986 cell surface; GO:0031091 platelet alpha granule; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0030674 protein binding, bridging; GO:0005102 receptor binding; GO:0005488 binding; GO:0043167 ion binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0060090 binding, bridging; GO:0005198 structural molecule activity; ","K03903","FGA; fibrinogen alpha chain","hsa04611 Platelet activation - Homo sapiens (human); hsa04610 Complement and coagulation cascades - Homo sapiens (human); ","IPR002181; IPR012290; IPR021996; IPR014716; IPR014715; ","\"Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain; Fibrinogen, alpha/beta/gamma chain, coiled coil domain; Fibrinogen alpha C domain; Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1; Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2; \"\r"]
["P02675","Fibrinogen beta chain OS=Homo sapiens OX=9606 GN=FGB","FGB",55.928,323.31,65.6,35,91,35,0.91,0.915,0.919,1.069,1.08,1.1,1.184,4.21E-5,"extracellular\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0098542 defense response to other organism; GO:0002793 positive regulation of peptide secretion; GO:0070555 response to interleukin-1; GO:0031347 regulation of defense response; GO:0043152 induction of bacterial agglutination; GO:0009607 response to biotic stimulus; GO:0042730 fibrinolysis; GO:0008152 metabolic process; GO:0065003 macromolecular complex assembly; GO:0007160 cell-matrix adhesion; GO:0044057 regulation of system process; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0019229 regulation of vasoconstriction; GO:0080090 regulation of primary metabolic process; GO:0030168 platelet activation; GO:1900026 positive regulation of substrate adhesion-dependent cell spreading; GO:0044763 single-organism cellular process; GO:0035296 regulation of tube diameter; GO:0010811 positive regulation of cell-substrate adhesion; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0006810 transport; GO:0048583 regulation of response to stimulus; GO:0098602 single organism cell adhesion; GO:0051223 regulation of protein transport; GO:0060548 negative regulation of cell death; GO:0044707 single-multicellular organism process; GO:0050880 regulation of blood vessel size; GO:0017157 regulation of exocytosis; GO:0002576 platelet degranulation; GO:0003018 vascular process in circulatory system; GO:0048519 negative regulation of biological process; GO:0090277 positive regulation of peptide hormone secretion; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0043062 extracellular structure organization; GO:0035150 regulation of tube size; GO:0050778 positive regulation of immune response; GO:0045785 positive regulation of cell adhesion; GO:0006950 response to stress; GO:0060284 regulation of cell development; GO:0032101 regulation of response to external stimulus; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0072378 blood coagulation, fibrin clot formation; GO:0030195 negative regulation of blood coagulation; GO:0045055 regulated exocytosis; GO:0061041 regulation of wound healing; GO:0031325 positive regulation of cellular metabolic process; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:0006955 immune response; GO:1903034 regulation of response to wounding; GO:0050819 negative regulation of coagulation; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0051046 regulation of secretion; GO:0016485 protein processing; GO:0097746 regulation of blood vessel diameter; GO:0009611 response to wounding; GO:0016337 single organismal cell-cell adhesion; GO:0007165 signal transduction; GO:0009893 positive regulation of metabolic process; GO:0031639 plasminogen activation; GO:1900046 regulation of hemostasis; GO:0002221 pattern recognition receptor signaling pathway; GO:0030198 extracellular matrix organization; GO:0019731 antibacterial humoral response; GO:0045937 positive regulation of phosphate metabolic process; GO:0034097 response to cytokine; GO:0098609 cell-cell adhesion; GO:0002764 immune response-regulating signaling pathway; GO:1903530 regulation of secretion by cell; GO:0023052 signaling; GO:0010038 response to metal ion; GO:1903035 negative regulation of response to wounding; GO:0032940 secretion by cell; GO:2001236 regulation of extrinsic apoptotic signaling pathway; GO:0006952 defense response; GO:0070271 protein complex biogenesis; GO:0051222 positive regulation of protein transport; GO:0016043 cellular component organization; GO:0043069 negative regulation of programmed cell death; GO:0060255 regulation of macromolecule metabolic process; GO:1903522 regulation of blood circulation; GO:0071310 cellular response to organic substance; GO:0010770 positive regulation of cell morphogenesis involved in differentiation; GO:0051707 response to other organism; GO:0045087 innate immune response; GO:0071704 organic substance metabolic process; GO:0034116 positive regulation of heterotypic cell-cell adhesion; GO:0043408 regulation of MAPK cascade; GO:0043066 negative regulation of apoptotic process; GO:0023056 positive regulation of signaling; GO:0008015 blood circulation; GO:0002757 immune response-activating signal transduction; GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors; GO:0051592 response to calcium ion; GO:0010647 positive regulation of cell communication; GO:0045595 regulation of cell differentiation; GO:0043623 cellular protein complex assembly; GO:0034622 cellular macromolecular complex assembly; GO:0050878 regulation of body fluid levels; GO:0042742 defense response to bacterium; GO:0051049 regulation of transport; GO:0001932 regulation of protein phosphorylation; GO:0045907 positive regulation of vasoconstriction; GO:0001934 positive regulation of protein phosphorylation; GO:0022407 regulation of cell-cell adhesion; GO:0043933 macromolecular complex subunit organization; GO:0071495 cellular response to endogenous stimulus; GO:0002684 positive regulation of immune system process; GO:0010467 gene expression; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0060627 regulation of vesicle-mediated transport; GO:0065008 regulation of biological quality; GO:0007596 blood coagulation; GO:2000351 regulation of endothelial cell apoptotic process; GO:0032270 positive regulation of cellular protein metabolic process; GO:0071345 cellular response to cytokine stimulus; GO:1904036 negative regulation of epithelial cell apoptotic process; GO:0009605 response to external stimulus; GO:0022610 biological adhesion; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0032102 negative regulation of response to external stimulus; GO:0007155 cell adhesion; GO:0009719 response to endogenous stimulus; GO:0010562 positive regulation of phosphorus metabolic process; GO:0042327 positive regulation of phosphorylation; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0031638 zymogen activation; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0051174 regulation of phosphorus metabolic process; GO:0045921 positive regulation of exocytosis; GO:0002758 innate immune response-activating signal transduction; GO:0019730 antimicrobial humoral response; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0046883 regulation of hormone secretion; GO:0050714 positive regulation of protein secretion; GO:0010817 regulation of hormone levels; GO:0010604 positive regulation of macromolecule metabolic process; GO:0002682 regulation of immune system process; GO:0050817 coagulation; GO:0003013 circulatory system process; GO:0051094 positive regulation of developmental process; GO:0051047 positive regulation of secretion; GO:0050794 regulation of cellular process; GO:0031399 regulation of protein modification process; GO:0030193 regulation of blood coagulation; GO:0043067 regulation of programmed cell death; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0034109 homotypic cell-cell adhesion; GO:0051239 regulation of multicellular organismal process; GO:0045597 positive regulation of cell differentiation; GO:1900047 negative regulation of hemostasis; GO:0031349 positive regulation of defense response; GO:0070372 regulation of ERK1 and ERK2 cascade; GO:1902578 single-organism localization; GO:1900024 regulation of substrate adhesion-dependent cell spreading; GO:0032880 regulation of protein localization; GO:0009966 regulation of signal transduction; GO:0009617 response to bacterium; GO:0006461 protein complex assembly; GO:1904035 regulation of epithelial cell apoptotic process; GO:0090087 regulation of peptide transport; GO:0002253 activation of immune response; GO:1902531 regulation of intracellular signal transduction; GO:0016192 vesicle-mediated transport; GO:2001237 negative regulation of extrinsic apoptotic signaling pathway; GO:0072376 protein activation cascade; GO:0044238 primary metabolic process; GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; GO:0044320 cellular response to leptin stimulus; GO:0030155 regulation of cell adhesion; GO:0051247 positive regulation of protein metabolic process; GO:1904951 positive regulation of establishment of protein localization; GO:0046887 positive regulation of hormone secretion; GO:0001775 cell activation; GO:0051179 localization; GO:0010810 regulation of cell-substrate adhesion; GO:0048584 positive regulation of response to stimulus; GO:0050793 regulation of developmental process; GO:0006887 exocytosis; GO:1902533 positive regulation of intracellular signal transduction; GO:0051241 negative regulation of multicellular organismal process; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:2001233 regulation of apoptotic signaling pathway; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0045088 regulation of innate immune response; GO:2000352 negative regulation of endothelial cell apoptotic process; GO:0002250 adaptive immune response; GO:0010035 response to inorganic substance; GO:0010720 positive regulation of cell development; GO:0070887 cellular response to chemical stimulus; GO:0071822 protein complex subunit organization; GO:0048522 positive regulation of cellular process; GO:0051050 positive regulation of transport; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0034114 regulation of heterotypic cell-cell adhesion; GO:1903532 positive regulation of secretion by cell; GO:0032870 cellular response to hormone stimulus; GO:0002224 toll-like receptor signaling pathway; GO:0051258 protein polymerization; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0070527 platelet aggregation; GO:0002218 activation of innate immune response; GO:0071347 cellular response to interleukin-1; GO:0006959 humoral immune response; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0007599 hemostasis; GO:0070201 regulation of establishment of protein localization; GO:0002791 regulation of peptide secretion; GO:0006508 proteolysis; GO:1903524 positive regulation of blood circulation; GO:0050708 regulation of protein secretion; GO:0009987 cellular process; GO:0003008 system process; GO:0045089 positive regulation of innate immune response; GO:0022409 positive regulation of cell-cell adhesion; GO:0031401 positive regulation of protein modification process; GO:0044321 response to leptin; GO:0048585 negative regulation of response to stimulus; GO:0061045 negative regulation of wound healing; GO:0048518 positive regulation of biological process; GO:0050818 regulation of coagulation; GO:0042060 wound healing; GO:0031589 cell-substrate adhesion; GO:0051246 regulation of protein metabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0090276 regulation of peptide hormone secretion; GO:0090066 regulation of anatomical structure size; GO:0051128 regulation of cellular component organization; GO:0009967 positive regulation of signal transduction; GO:0051604 protein maturation; GO:0009725 response to hormone; GO:0043410 positive regulation of MAPK cascade; GO:0022604 regulation of cell morphogenesis; GO:0070374 positive regulation of ERK1 and ERK2 cascade; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005938 cell cortex; GO:0009897 external side of plasma membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0099568 cytoplasmic region; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0098552 side of membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0005577 fibrinogen complex; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0072562 blood microparticle; GO:0060205 cytoplasmic vesicle lumen; GO:0044459 plasma membrane part; GO:0031093 platelet alpha granule lumen; GO:0009986 cell surface; GO:0031091 platelet alpha granule; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0030674 protein binding, bridging; GO:0051087 chaperone binding; GO:0005102 receptor binding; GO:0005488 binding; GO:0005515 protein binding; GO:0060090 binding, bridging; GO:0005198 structural molecule activity; ","K03904","FGB; fibrinogen beta chain","hsa04611 Platelet activation - Homo sapiens (human); hsa04610 Complement and coagulation cascades - Homo sapiens (human); ","IPR002181; IPR012290; IPR014716; IPR014715; ","\"Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain; Fibrinogen, alpha/beta/gamma chain, coiled coil domain; Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1; Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2; \"\r"]
["P02679","Fibrinogen gamma chain OS=Homo sapiens OX=9606 GN=FGG","FGG",51.511,225.65,49.7,22,63,22,0.936,0.892,0.91,1.091,1.079,1.065,1.182,0.000436,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0021700 developmental maturation; GO:0010941 regulation of cell death; GO:0002793 positive regulation of peptide secretion; GO:0070555 response to interleukin-1; GO:0031347 regulation of defense response; GO:0042730 fibrinolysis; GO:0008152 metabolic process; GO:0065003 macromolecular complex assembly; GO:0007160 cell-matrix adhesion; GO:0044057 regulation of system process; GO:0009306 protein secretion; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0019229 regulation of vasoconstriction; GO:0080090 regulation of primary metabolic process; GO:0030168 platelet activation; GO:1900026 positive regulation of substrate adhesion-dependent cell spreading; GO:0044763 single-organism cellular process; GO:0035296 regulation of tube diameter; GO:0010811 positive regulation of cell-substrate adhesion; GO:0050776 regulation of immune response; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0006810 transport; GO:0048583 regulation of response to stimulus; GO:0098602 single organism cell adhesion; GO:0051223 regulation of protein transport; GO:0060548 negative regulation of cell death; GO:0044707 single-multicellular organism process; GO:0050880 regulation of blood vessel size; GO:0010543 regulation of platelet activation; GO:0017157 regulation of exocytosis; GO:0022408 negative regulation of cell-cell adhesion; GO:0002576 platelet degranulation; GO:0003018 vascular process in circulatory system; GO:0071354 cellular response to interleukin-6; GO:0048519 negative regulation of biological process; GO:0090277 positive regulation of peptide hormone secretion; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0043062 extracellular structure organization; GO:0035150 regulation of tube size; GO:0050778 positive regulation of immune response; GO:0045785 positive regulation of cell adhesion; GO:0006950 response to stress; GO:0060284 regulation of cell development; GO:0002376 immune system process; GO:0032101 regulation of response to external stimulus; GO:0010033 response to organic substance; GO:0072378 blood coagulation, fibrin clot formation; GO:0034110 regulation of homotypic cell-cell adhesion; GO:0030195 negative regulation of blood coagulation; GO:0045055 regulated exocytosis; GO:0061041 regulation of wound healing; GO:0031325 positive regulation of cellular metabolic process; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:1903034 regulation of response to wounding; GO:0050819 negative regulation of coagulation; GO:0009968 negative regulation of signal transduction; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0051046 regulation of secretion; GO:0016485 protein processing; GO:0097746 regulation of blood vessel diameter; GO:0009611 response to wounding; GO:0016337 single organismal cell-cell adhesion; GO:0007165 signal transduction; GO:0009893 positive regulation of metabolic process; GO:0031639 plasminogen activation; GO:0048469 cell maturation; GO:1900046 regulation of hemostasis; GO:0002221 pattern recognition receptor signaling pathway; GO:0030198 extracellular matrix organization; GO:0033036 macromolecule localization; GO:0045937 positive regulation of phosphate metabolic process; GO:0034097 response to cytokine; GO:0098609 cell-cell adhesion; GO:0002764 immune response-regulating signaling pathway; GO:1903530 regulation of secretion by cell; GO:0023052 signaling; GO:0010038 response to metal ion; GO:1903035 negative regulation of response to wounding; GO:0032940 secretion by cell; GO:2001236 regulation of extrinsic apoptotic signaling pathway; GO:0070271 protein complex biogenesis; GO:0051222 positive regulation of protein transport; GO:0016043 cellular component organization; GO:0043069 negative regulation of programmed cell death; GO:0060255 regulation of macromolecule metabolic process; GO:1903522 regulation of blood circulation; GO:0071310 cellular response to organic substance; GO:0010770 positive regulation of cell morphogenesis involved in differentiation; GO:0090331 negative regulation of platelet aggregation; GO:0071704 organic substance metabolic process; GO:0034116 positive regulation of heterotypic cell-cell adhesion; GO:0030154 cell differentiation; GO:0043408 regulation of MAPK cascade; GO:0043066 negative regulation of apoptotic process; GO:0023056 positive regulation of signaling; GO:0008015 blood circulation; GO:0002757 immune response-activating signal transduction; GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors; GO:0051592 response to calcium ion; GO:0010647 positive regulation of cell communication; GO:0045595 regulation of cell differentiation; GO:0043623 cellular protein complex assembly; GO:0034622 cellular macromolecular complex assembly; GO:0050878 regulation of body fluid levels; GO:0051049 regulation of transport; GO:0001932 regulation of protein phosphorylation; GO:0010544 negative regulation of platelet activation; GO:0045907 positive regulation of vasoconstriction; GO:0001934 positive regulation of protein phosphorylation; GO:0022407 regulation of cell-cell adhesion; GO:0043933 macromolecular complex subunit organization; GO:0070741 response to interleukin-6; GO:0002684 positive regulation of immune system process; GO:0010467 gene expression; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0060627 regulation of vesicle-mediated transport; GO:0065008 regulation of biological quality; GO:0007596 blood coagulation; GO:2000351 regulation of endothelial cell apoptotic process; GO:0032270 positive regulation of cellular protein metabolic process; GO:0071345 cellular response to cytokine stimulus; GO:0015031 protein transport; GO:1904036 negative regulation of epithelial cell apoptotic process; GO:0022610 biological adhesion; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0032102 negative regulation of response to external stimulus; GO:0007155 cell adhesion; GO:0010562 positive regulation of phosphorus metabolic process; GO:0042327 positive regulation of phosphorylation; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0008104 protein localization; GO:0031638 zymogen activation; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0051174 regulation of phosphorus metabolic process; GO:0045921 positive regulation of exocytosis; GO:0002758 innate immune response-activating signal transduction; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0046883 regulation of hormone secretion; GO:0050714 positive regulation of protein secretion; GO:0010817 regulation of hormone levels; GO:0010604 positive regulation of macromolecule metabolic process; GO:0002682 regulation of immune system process; GO:0050817 coagulation; GO:0003013 circulatory system process; GO:0051094 positive regulation of developmental process; GO:0051047 positive regulation of secretion; GO:0050794 regulation of cellular process; GO:0007162 negative regulation of cell adhesion; GO:0031399 regulation of protein modification process; GO:0030193 regulation of blood coagulation; GO:0043067 regulation of programmed cell death; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:0034109 homotypic cell-cell adhesion; GO:0051239 regulation of multicellular organismal process; GO:0045597 positive regulation of cell differentiation; GO:0050866 negative regulation of cell activation; GO:1900047 negative regulation of hemostasis; GO:0031349 positive regulation of defense response; GO:0070372 regulation of ERK1 and ERK2 cascade; GO:1902578 single-organism localization; GO:1900024 regulation of substrate adhesion-dependent cell spreading; GO:0032880 regulation of protein localization; GO:0009966 regulation of signal transduction; GO:0006461 protein complex assembly; GO:1904035 regulation of epithelial cell apoptotic process; GO:0090087 regulation of peptide transport; GO:0002253 activation of immune response; GO:1902531 regulation of intracellular signal transduction; GO:0016192 vesicle-mediated transport; GO:0036345 platelet maturation; GO:0071702 organic substance transport; GO:2001237 negative regulation of extrinsic apoptotic signaling pathway; GO:0072376 protein activation cascade; GO:0044238 primary metabolic process; GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; GO:0030155 regulation of cell adhesion; GO:0045184 establishment of protein localization; GO:0051247 positive regulation of protein metabolic process; GO:1904951 positive regulation of establishment of protein localization; GO:0046887 positive regulation of hormone secretion; GO:0001775 cell activation; GO:0051179 localization; GO:0010810 regulation of cell-substrate adhesion; GO:0048584 positive regulation of response to stimulus; GO:0050793 regulation of developmental process; GO:0006887 exocytosis; GO:1902533 positive regulation of intracellular signal transduction; GO:0051241 negative regulation of multicellular organismal process; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:2001233 regulation of apoptotic signaling pathway; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0045088 regulation of innate immune response; GO:2000352 negative regulation of endothelial cell apoptotic process; GO:0010035 response to inorganic substance; GO:0010720 positive regulation of cell development; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0071822 protein complex subunit organization; GO:0048522 positive regulation of cellular process; GO:0051050 positive regulation of transport; GO:0050865 regulation of cell activation; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0034114 regulation of heterotypic cell-cell adhesion; GO:1903532 positive regulation of secretion by cell; GO:0002224 toll-like receptor signaling pathway; GO:0051258 protein polymerization; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0048856 anatomical structure development; GO:0070527 platelet aggregation; GO:0002218 activation of innate immune response; GO:0090330 regulation of platelet aggregation; GO:0071347 cellular response to interleukin-1; GO:0050896 response to stimulus; GO:0007599 hemostasis; GO:0048468 cell development; GO:0070201 regulation of establishment of protein localization; GO:0002791 regulation of peptide secretion; GO:0006508 proteolysis; GO:1903524 positive regulation of blood circulation; GO:0050708 regulation of protein secretion; GO:0009987 cellular process; GO:0003008 system process; GO:0045089 positive regulation of innate immune response; GO:0022409 positive regulation of cell-cell adhesion; GO:0031401 positive regulation of protein modification process; GO:0048585 negative regulation of response to stimulus; GO:0061045 negative regulation of wound healing; GO:0048518 positive regulation of biological process; GO:0050818 regulation of coagulation; GO:0042060 wound healing; GO:0031589 cell-substrate adhesion; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0034111 negative regulation of homotypic cell-cell adhesion; GO:0090276 regulation of peptide hormone secretion; GO:0090066 regulation of anatomical structure size; GO:0051128 regulation of cellular component organization; GO:0009967 positive regulation of signal transduction; GO:0051604 protein maturation; GO:0043410 positive regulation of MAPK cascade; GO:0070374 positive regulation of ERK1 and ERK2 cascade; GO:0022604 regulation of cell morphogenesis; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005938 cell cortex; GO:0009897 external side of plasma membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0099568 cytoplasmic region; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0098552 side of membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0005577 fibrinogen complex; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0072562 blood microparticle; GO:0060205 cytoplasmic vesicle lumen; GO:0044459 plasma membrane part; GO:0031093 platelet alpha granule lumen; GO:0009986 cell surface; GO:0031091 platelet alpha granule; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0050839 cell adhesion molecule binding; GO:0042802 identical protein binding; GO:0030674 protein binding, bridging; GO:0005102 receptor binding; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0043167 ion binding; GO:0046983 protein dimerization activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0060090 binding, bridging; GO:0005198 structural molecule activity; ","K03905","FGG; fibrinogen gamma chain","hsa04611 Platelet activation - Homo sapiens (human); hsa04610 Complement and coagulation cascades - Homo sapiens (human); hsa05150 Staphylococcus aureus infection - Homo sapiens (human); ","IPR002181; IPR012290; IPR014716; IPR014715; ","\"Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain; Fibrinogen, alpha/beta/gamma chain, coiled coil domain; Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1; Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2; \"\r"]
["P02724","Glycophorin-A OS=Homo sapiens OX=9606 GN=GYPA","GYPA",16.331,8.2588,20.7,2,3,2,0.762,1.034,0.848,1.159,1.159,1.036,1.269,0.0651,"plasma membrane\r","GO:0044409 entry into host; GO:0016477 cell migration; GO:0051674 localization of cell; GO:0051806 entry into cell of other organism involved in symbiotic interaction; GO:0019058 viral life cycle; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0002376 immune system process; GO:0044764 multi-organism cellular process; GO:0048870 cell motility; GO:0051701 interaction with host; GO:0051704 multi-organism process; GO:0030260 entry into host cell; GO:0050900 leukocyte migration; GO:0016032 viral process; GO:0051828 entry into other organism involved in symbiotic interaction; GO:0006928 movement of cell or subcellular component; GO:0040011 locomotion; GO:0051179 localization; GO:0044419 interspecies interaction between organisms; GO:0009987 cellular process; GO:0046718 viral entry into host cell; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0060089 molecular transducer activity; GO:0005515 protein binding; GO:0004872 receptor activity; GO:0042802 identical protein binding; GO:0001618 virus receptor activity; GO:0005488 binding; ","K06575","GYPA; glycophorin A","hsa05144 Malaria - Homo sapiens (human); hsa04640 Hematopoietic cell lineage - Homo sapiens (human); "]
["P02730","Band 3 anion transport protein OS=Homo sapiens OX=9606 GN=SLC4A1","SLC4A1",101.79,239.26,24.6,20,56,20,0.852,0.838,0.86,1.16,1.118,1.133,1.338,2.25e-05,"plasma membrane\r","GO:0098661 inorganic anion transmembrane transport; GO:0065008 regulation of biological quality; GO:0034220 ion transmembrane transport; GO:0006885 regulation of pH; GO:0030003 cellular cation homeostasis; GO:0030641 regulation of cellular pH; GO:0030004 cellular monovalent inorganic cation homeostasis; GO:0044699 single-organism process; GO:0006821 chloride transport; GO:0055082 cellular chemical homeostasis; GO:0098656 anion transmembrane transport; GO:1902476 chloride transmembrane transport; GO:0051234 establishment of localization; GO:0042592 homeostatic process; GO:0055080 cation homeostasis; GO:0015701 bicarbonate transport; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0055067 monovalent inorganic cation homeostasis; GO:0050801 ion homeostasis; GO:0098660 inorganic ion transmembrane transport; GO:0044763 single-organism cellular process; GO:0098771 inorganic ion homeostasis; GO:0019725 cellular homeostasis; GO:0071702 organic substance transport; GO:0006810 transport; GO:0006820 anion transport; GO:0055085 transmembrane transport; GO:0015711 organic anion transport; GO:0051453 regulation of intracellular pH; GO:0006873 cellular ion homeostasis; GO:0006811 ion transport; GO:0051179 localization; GO:0015698 inorganic anion transport; GO:0065007 biological regulation; ","GO:0016323 basolateral plasma membrane; GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005938 cell cortex; GO:0071944 cell periphery; GO:0030016 myofibril; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0099568 cytoplasmic region; GO:0030863 cortical cytoskeleton; GO:0031224 intrinsic component of membrane; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0030018 Z disc; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0031674 I band; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005856 cytoskeleton; GO:0098590 plasma membrane region; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:1903561 extracellular vesicle; GO:0043292 contractile fiber; GO:0043227 membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0031226 intrinsic component of plasma membrane; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0099081 supramolecular polymer; GO:0043226 organelle; GO:0072562 blood microparticle; GO:0044459 plasma membrane part; GO:0044448 cell cortex part; GO:0030017 sarcomere; GO:0044449 contractile fiber part; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0022804 active transmembrane transporter activity; GO:0015291 secondary active transmembrane transporter activity; GO:0005452 inorganic anion exchanger activity; GO:0015075 ion transmembrane transporter activity; GO:0046983 protein dimerization activity; GO:0015106 bicarbonate transmembrane transporter activity; GO:0015301 anion:anion antiporter activity; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0030506 ankyrin binding; GO:0015297 antiporter activity; GO:0015103 inorganic anion transmembrane transporter activity; GO:0099516 ion antiporter activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0015108 chloride transmembrane transporter activity; GO:0043495 protein anchor; GO:0042802 identical protein binding; GO:0008092 cytoskeletal protein binding; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0008514 organic anion transmembrane transporter activity; GO:0022857 transmembrane transporter activity; GO:0005215 transporter activity; GO:0008509 anion transmembrane transporter activity; ","K06573","SLC4A1; solute carrier family 4 (anion exchanger), member 1","hsa04966 Collecting duct acid secretion - Homo sapiens (human); ","IPR011531; IPR013769; IPR016152; ","\"Bicarbonate transporter, C-terminal; Band 3 cytoplasmic domain; Phosphotransferase/anion transporter; \"\r"]
["P02743","Serum amyloid P-component OS=Homo sapiens OX=9606 GN=APCS","APCS",25.387,58.824,39.9,9,20,9,1.036,0.975,0.977,0.951,1.041,1.003,1.002,0.953,"extracellular\r","GO:0044085 cellular component biogenesis; GO:0051093 negative regulation of developmental process; GO:0065008 regulation of biological quality; GO:0002762 negative regulation of myeloid leukocyte differentiation; GO:0045637 regulation of myeloid cell differentiation; GO:0044359 modulation of molecular function in other organism; GO:1903016 negative regulation of exo-alpha-sialidase activity; GO:0051241 negative regulation of multicellular organismal process; GO:0044866 modulation by host of viral exo-alpha-sialidase activity; GO:0035821 modification of morphology or physiology of other organism; GO:0031347 regulation of defense response; GO:0044362 negative regulation of molecular function in other organism; GO:0044237 cellular metabolic process; GO:0006457 protein folding; GO:0008152 metabolic process; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0032102 negative regulation of response to external stimulus; GO:0044003 modification by symbiont of host morphology or physiology; GO:0046596 regulation of viral entry into host cell; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0045596 negative regulation of cell differentiation; GO:0044419 interspecies interaction between organisms; GO:1903019 negative regulation of glycoprotein metabolic process; GO:0048525 negative regulation of viral process; GO:0052428 modification by host of symbiont molecular function; GO:0071822 protein complex subunit organization; GO:0044867 modulation by host of viral catalytic activity; GO:0045638 negative regulation of myeloid cell differentiation; GO:0080090 regulation of primary metabolic process; GO:0046597 negative regulation of viral entry into host cell; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0031323 regulation of cellular metabolic process; GO:0043086 negative regulation of catalytic activity; GO:0044788 modulation by host of viral process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051704 multi-organism process; GO:1903035 negative regulation of response to wounding; GO:0002683 negative regulation of immune system process; GO:0045655 regulation of monocyte differentiation; GO:0050789 regulation of biological process; GO:0052204 negative regulation of molecular function in other organism involved in symbiotic interaction; GO:0044871 negative regulation by host of viral glycoprotein metabolic process; GO:0006953 acute-phase response; GO:0051336 regulation of hydrolase activity; GO:0044869 negative regulation by host of viral exo-alpha-sialidase activity; GO:0002526 acute inflammatory response; GO:0050790 regulation of catalytic activity; GO:1902105 regulation of leukocyte differentiation; GO:0006954 inflammatory response; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0052203 modulation of catalytic activity in other organism involved in symbiotic interaction; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0002682 regulation of immune system process; GO:0044092 negative regulation of molecular function; GO:0006952 defense response; GO:0070271 protein complex biogenesis; GO:0051851 modification by host of symbiont morphology or physiology; GO:2000026 regulation of multicellular organismal development; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0044793 negative regulation by host of viral process; GO:0050728 negative regulation of inflammatory response; GO:0060255 regulation of macromolecule metabolic process; GO:0044267 cellular protein metabolic process; GO:0002673 regulation of acute inflammatory response; GO:0052422 modulation by host of symbiont catalytic activity; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0080134 regulation of response to stress; GO:0031324 negative regulation of cellular metabolic process; GO:0002674 negative regulation of acute inflammatory response; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:0051346 negative regulation of hydrolase activity; GO:0045087 innate immune response; GO:1903706 regulation of hemopoiesis; GO:1903901 negative regulation of viral life cycle; GO:0071704 organic substance metabolic process; GO:0051817 modification of morphology or physiology of other organism involved in symbiotic interaction; GO:0044868 modulation by host of viral molecular function; GO:0044870 modulation by host of viral glycoprotein metabolic process; GO:1903707 negative regulation of hemopoiesis; GO:0051702 interaction with symbiont; GO:0045656 negative regulation of monocyte differentiation; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0045595 regulation of cell differentiation; GO:0043623 cellular protein complex assembly; GO:0031348 negative regulation of defense response; GO:0034622 cellular macromolecular complex assembly; GO:0006950 response to stress; GO:0052403 negative regulation by host of symbiont catalytic activity; GO:0043900 regulation of multi-organism process; GO:0050792 regulation of viral process; GO:1903018 regulation of glycoprotein metabolic process; GO:0032101 regulation of response to external stimulus; GO:0002376 immune system process; GO:0048585 negative regulation of response to stimulus; GO:0051701 interaction with host; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0061045 negative regulation of wound healing; GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction; GO:0043933 macromolecular complex subunit organization; GO:1903015 regulation of exo-alpha-sialidase activity; GO:0043901 negative regulation of multi-organism process; GO:0052055 modulation by symbiont of host molecular function; GO:1902106 negative regulation of leukocyte differentiation; GO:0052205 modulation of molecular function in other organism involved in symbiotic interaction; GO:0052405 negative regulation by host of symbiont molecular function; GO:0061041 regulation of wound healing; GO:0051246 regulation of protein metabolic process; GO:0002761 regulation of myeloid leukocyte differentiation; GO:0050727 regulation of inflammatory response; GO:0051248 negative regulation of protein metabolic process; GO:0051131 chaperone-mediated protein complex assembly; GO:1903900 regulation of viral life cycle; GO:0006955 immune response; GO:0050793 regulation of developmental process; GO:1903034 regulation of response to wounding; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0072562 blood microparticle; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0001849 complement component C1q binding; GO:0001846 opsonin binding; GO:0005488 binding; GO:0043167 ion binding; GO:0001848 complement binding; GO:0030246 carbohydrate binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0005509 calcium ion binding; GO:0051082 unfolded protein binding; GO:0046790 virion binding; ",{"$nulls":3},"IPR013320; ","Concanavalin A-like lectin/glucanase domain; \r"]
["P02745","Complement C1q subcomponent subunit A OS=Homo sapiens OX=9606 GN=C1QA","C1QA",26.016,4.1227,4.1,1,2,1,1.098,1.107,0.929,0.984,1.005,0.897,0.921,0.296,"extracellular\r","GO:0044700 single organism signaling; GO:0016064 immunoglobulin mediated immune response; GO:0002252 immune effector process; GO:0044699 single-organism process; GO:0006959 humoral immune response; GO:0050896 response to stimulus; GO:0045087 innate immune response; GO:0019724 B cell mediated immunity; GO:0071704 organic substance metabolic process; GO:0006956 complement activation; GO:0008152 metabolic process; GO:0007154 cell communication; GO:0010039 response to iron ion; GO:0002250 adaptive immune response; GO:0006958 complement activation, classical pathway; GO:0006508 proteolysis; GO:0010035 response to inorganic substance; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0002449 lymphocyte mediated immunity; GO:0009987 cellular process; GO:0050778 positive regulation of immune response; GO:0002253 activation of immune response; GO:0002443 leukocyte mediated immunity; GO:0006950 response to stress; GO:0044763 single-organism cellular process; GO:0002376 immune system process; GO:0072376 protein activation cascade; GO:0044238 primary metabolic process; GO:0023052 signaling; GO:0048518 positive regulation of biological process; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0010038 response to metal ion; GO:0050776 regulation of immune response; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0007267 cell-cell signaling; GO:0048583 regulation of response to stimulus; GO:0002684 positive regulation of immune system process; GO:0002682 regulation of immune system process; GO:0006952 defense response; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0048584 positive regulation of response to stimulus; GO:0006955 immune response; GO:0065007 biological regulation; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0032991 macromolecular complex; GO:0005602 complement component C1 complex; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0005581 collagen trimer; GO:0043230 extracellular organelle; ","GO:0004252 serine-type endopeptidase activity; GO:0004175 endopeptidase activity; GO:0008233 peptidase activity; GO:0003824 catalytic activity; GO:0017171 serine hydrolase activity; GO:0005488 binding; GO:0008236 serine-type peptidase activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0005515 protein binding; GO:0016787 hydrolase activity; ","K03986","C1QA; complement C1q subcomponent subunit A","hsa05142 Chagas disease (American trypanosomiasis) - Homo sapiens (human); hsa05322 Systemic lupus erythematosus - Homo sapiens (human); hsa05133 Pertussis - Homo sapiens (human); hsa04610 Complement and coagulation cascades - Homo sapiens (human); hsa05150 Staphylococcus aureus infection - Homo sapiens (human); hsa05020 Prion diseases - Homo sapiens (human); ","IPR008983; IPR001073; ","Tumour necrosis factor-like domain; C1q domain; \r"]
["P02746","Complement C1q subcomponent subunit B OS=Homo sapiens OX=9606 GN=C1QB","C1QB",26.721,32.943,17.8,4,7,4,0.996,1.028,0.969,1.022,0.938,0.875,0.947,0.309,"extracellular\r","GO:0044707 single-multicellular organism process; GO:0016064 immunoglobulin mediated immune response; GO:0002252 immune effector process; GO:0044699 single-organism process; GO:0006959 humoral immune response; GO:0050896 response to stimulus; GO:0045087 innate immune response; GO:0019724 B cell mediated immunity; GO:0071704 organic substance metabolic process; GO:0006956 complement activation; GO:0008152 metabolic process; GO:0002250 adaptive immune response; GO:0006958 complement activation, classical pathway; GO:0006508 proteolysis; GO:0007275 multicellular organism development; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0002449 lymphocyte mediated immunity; GO:0050778 positive regulation of immune response; GO:0032502 developmental process; GO:0002253 activation of immune response; GO:0002443 leukocyte mediated immunity; GO:0006950 response to stress; GO:0048731 system development; GO:0002376 immune system process; GO:0072376 protein activation cascade; GO:0048839 inner ear development; GO:0044238 primary metabolic process; GO:0032501 multicellular organismal process; GO:0048518 positive regulation of biological process; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0050776 regulation of immune response; GO:0048513 animal organ development; GO:0043583 ear development; GO:0050789 regulation of biological process; GO:0044767 single-organism developmental process; GO:0048583 regulation of response to stimulus; GO:0002684 positive regulation of immune system process; GO:0002682 regulation of immune system process; GO:0006952 defense response; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0007423 sensory organ development; GO:0048584 positive regulation of response to stimulus; GO:0006955 immune response; GO:0048856 anatomical structure development; GO:0065007 biological regulation; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0072562 blood microparticle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0032991 macromolecular complex; GO:0005602 complement component C1 complex; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0005581 collagen trimer; GO:0043230 extracellular organelle; ","GO:0004252 serine-type endopeptidase activity; GO:0004175 endopeptidase activity; GO:0008233 peptidase activity; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0017171 serine hydrolase activity; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0046983 protein dimerization activity; GO:0008236 serine-type peptidase activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0005515 protein binding; GO:0016787 hydrolase activity; ","K03987","C1QB; complement C1q subcomponent subunit B","hsa05142 Chagas disease (American trypanosomiasis) - Homo sapiens (human); hsa05322 Systemic lupus erythematosus - Homo sapiens (human); hsa05133 Pertussis - Homo sapiens (human); hsa04610 Complement and coagulation cascades - Homo sapiens (human); hsa05150 Staphylococcus aureus infection - Homo sapiens (human); hsa05020 Prion diseases - Homo sapiens (human); ","IPR008983; IPR001073; ","Tumour necrosis factor-like domain; C1q domain; \r"]
["P02747","Complement C1q subcomponent subunit C OS=Homo sapiens OX=9606 GN=C1QC","C1QC",25.773,29.548,21.2,4,7,4,0.97,1.009,1.012,0.942,1.053,1.064,1.023,0.635,"extracellular\r","GO:0050794 regulation of cellular process; GO:0051093 negative regulation of developmental process; GO:0016064 immunoglobulin mediated immune response; GO:0002762 negative regulation of myeloid leukocyte differentiation; GO:0002252 immune effector process; GO:0045637 regulation of myeloid cell differentiation; GO:0030853 negative regulation of granulocyte differentiation; GO:0051241 negative regulation of multicellular organismal process; GO:0006959 humoral immune response; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:0045087 innate immune response; GO:0051239 regulation of multicellular organismal process; GO:0019724 B cell mediated immunity; GO:1903706 regulation of hemopoiesis; GO:0030852 regulation of granulocyte differentiation; GO:0071704 organic substance metabolic process; GO:0006956 complement activation; GO:0008152 metabolic process; GO:0002250 adaptive immune response; GO:0006958 complement activation, classical pathway; GO:0006508 proteolysis; GO:1903707 negative regulation of hemopoiesis; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0002449 lymphocyte mediated immunity; GO:0045596 negative regulation of cell differentiation; GO:0050778 positive regulation of immune response; GO:0045595 regulation of cell differentiation; GO:0002253 activation of immune response; GO:0002443 leukocyte mediated immunity; GO:0006950 response to stress; GO:0045638 negative regulation of myeloid cell differentiation; GO:0002376 immune system process; GO:0072376 protein activation cascade; GO:0045650 negative regulation of macrophage differentiation; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0050776 regulation of immune response; GO:0002683 negative regulation of immune system process; GO:1902106 negative regulation of leukocyte differentiation; GO:0050789 regulation of biological process; GO:1902105 regulation of leukocyte differentiation; GO:0002761 regulation of myeloid leukocyte differentiation; GO:0048583 regulation of response to stimulus; GO:0002684 positive regulation of immune system process; GO:0002682 regulation of immune system process; GO:0006952 defense response; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0048584 positive regulation of response to stimulus; GO:0006955 immune response; GO:0045649 regulation of macrophage differentiation; GO:0050793 regulation of developmental process; GO:2000026 regulation of multicellular organismal development; GO:0065007 biological regulation; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0072562 blood microparticle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0032991 macromolecular complex; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0005581 collagen trimer; GO:0043230 extracellular organelle; ","GO:0004252 serine-type endopeptidase activity; GO:0004175 endopeptidase activity; GO:0008233 peptidase activity; GO:0003824 catalytic activity; GO:0017171 serine hydrolase activity; GO:0005488 binding; GO:0008236 serine-type peptidase activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0005515 protein binding; GO:0016787 hydrolase activity; ","K03988","C1QG; complement C1q subcomponent subunit C","hsa05142 Chagas disease (American trypanosomiasis) - Homo sapiens (human); hsa05322 Systemic lupus erythematosus - Homo sapiens (human); hsa05133 Pertussis - Homo sapiens (human); hsa04610 Complement and coagulation cascades - Homo sapiens (human); hsa05150 Staphylococcus aureus infection - Homo sapiens (human); hsa05020 Prion diseases - Homo sapiens (human); ","IPR008983; IPR001073; ","Tumour necrosis factor-like domain; C1q domain; \r"]
["P02748","Complement component C9 OS=Homo sapiens OX=9606 GN=C9","C9",63.173,84.45,33.5,16,27,15,1.034,0.951,1.022,1.012,0.99,1.009,1.001,0.946,"extracellular\r","GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0016064 immunoglobulin mediated immune response; GO:0001907 killing by symbiont of host cells; GO:0044764 multi-organism cellular process; GO:0035821 modification of morphology or physiology of other organism; GO:0031347 regulation of defense response; GO:0044004 disruption by symbiont of host cell; GO:0006956 complement activation; GO:0008152 metabolic process; GO:0051883 killing of cells in other organism involved in symbiotic interaction; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0002250 adaptive immune response; GO:0044003 modification by symbiont of host morphology or physiology; GO:0006958 complement activation, classical pathway; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0044419 interspecies interaction between organisms; GO:0001906 cell killing; GO:0002697 regulation of immune effector process; GO:0001897 cytolysis by symbiont of host cells; GO:0010468 regulation of gene expression; GO:0002443 leukocyte mediated immunity; GO:0071822 protein complex subunit organization; GO:0080090 regulation of primary metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0051704 multi-organism process; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0050776 regulation of immune response; GO:0051715 cytolysis in other organism; GO:0050789 regulation of biological process; GO:0044179 hemolysis in other organism; GO:0048583 regulation of response to stimulus; GO:0019222 regulation of metabolic process; GO:0002682 regulation of immune system process; GO:0006952 defense response; GO:1903317 regulation of protein maturation; GO:0070271 protein complex biogenesis; GO:0030449 regulation of complement activation; GO:0016043 cellular component organization; GO:2000257 regulation of protein activation cascade; GO:0019835 cytolysis; GO:0051260 protein homooligomerization; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0002920 regulation of humoral immune response; GO:0002673 regulation of acute inflammatory response; GO:0006959 humoral immune response; GO:0080134 regulation of response to stress; GO:0050896 response to stimulus; GO:0045087 innate immune response; GO:0051817 modification of morphology or physiology of other organism involved in symbiotic interaction; GO:0051259 protein oligomerization; GO:0071704 organic substance metabolic process; GO:0019724 B cell mediated immunity; GO:0052331 hemolysis in other organism involved in symbiotic interaction; GO:0031640 killing of cells of other organism; GO:0002449 lymphocyte mediated immunity; GO:0009987 cellular process; GO:0050778 positive regulation of immune response; GO:0006461 protein complex assembly; GO:0051818 disruption of cells of other organism involved in symbiotic interaction; GO:0019836 hemolysis by symbiont of host erythrocytes; GO:0002253 activation of immune response; GO:0006950 response to stress; GO:0032101 regulation of response to external stimulus; GO:0002376 immune system process; GO:0072376 protein activation cascade; GO:0030162 regulation of proteolysis; GO:0051701 interaction with host; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0043933 macromolecular complex subunit organization; GO:0051801 cytolysis in other organism involved in symbiotic interaction; GO:0006957 complement activation, alternative pathway; GO:0051246 regulation of protein metabolic process; GO:0002684 positive regulation of immune system process; GO:0050727 regulation of inflammatory response; GO:0070613 regulation of protein processing; GO:0044364 disruption of cells of other organism; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0006955 immune response; GO:0048584 positive regulation of response to stimulus; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0098796 membrane protein complex; GO:0044216 other organism cell; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0070062 extracellular exosome; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0044215 other organism; GO:0044279 other organism membrane; GO:0043227 membrane-bounded organelle; GO:0031226 intrinsic component of plasma membrane; GO:0044217 other organism part; GO:0046930 pore complex; GO:0098797 plasma membrane protein complex; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0044218 other organism cell membrane; GO:0072562 blood microparticle; GO:0044459 plasma membrane part; GO:0005579 membrane attack complex; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ","K04000","C9; complement component 9","hsa05322 Systemic lupus erythematosus - Homo sapiens (human); hsa04610 Complement and coagulation cascades - Homo sapiens (human); hsa05146 Amoebiasis - Homo sapiens (human); hsa05020 Prion diseases - Homo sapiens (human); ","IPR020864; IPR009030; ","Membrane attack complex component/perforin (MACPF) domain; Growth factor receptor cysteine-rich domain; \r"]
["P02749","Beta-2-glycoprotein 1 OS=Homo sapiens OX=9606 GN=APOH","APOH",38.298,155.67,40.6,12,34,12,1.059,1.056,1.037,0.961,0.97,0.94,0.911,0.0012,"extracellular\r","GO:0065008 regulation of biological quality; GO:0007596 blood coagulation; GO:0010941 regulation of cell death; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0010594 regulation of endothelial cell migration; GO:0008285 negative regulation of cell proliferation; GO:0034391 regulation of smooth muscle cell apoptotic process; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0050678 regulation of epithelial cell proliferation; GO:0044093 positive regulation of molecular function; GO:0006639 acylglycerol metabolic process; GO:0032102 negative regulation of response to external stimulus; GO:0090303 positive regulation of wound healing; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0031638 zymogen activation; GO:0030194 positive regulation of blood coagulation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0006869 lipid transport; GO:0010632 regulation of epithelial cell migration; GO:0060191 regulation of lipase activity; GO:0044763 single-organism cellular process; GO:2000146 negative regulation of cell motility; GO:1901343 negative regulation of vasculature development; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:0010660 regulation of muscle cell apoptotic process; GO:0051336 regulation of hydrolase activity; GO:1900048 positive regulation of hemostasis; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:0045765 regulation of angiogenesis; GO:0050817 coagulation; GO:0060548 negative regulation of cell death; GO:1903036 positive regulation of response to wounding; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0042127 regulation of cell proliferation; GO:0043067 regulation of programmed cell death; GO:0030193 regulation of blood coagulation; GO:0002576 platelet degranulation; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:0051239 regulation of multicellular organismal process; GO:1900047 negative regulation of hemostasis; GO:1902578 single-organism localization; GO:0051345 positive regulation of hydrolase activity; GO:0061365 positive regulation of triglyceride lipase activity; GO:2000145 regulation of cell motility; GO:0051004 regulation of lipoprotein lipase activity; GO:0001936 regulation of endothelial cell proliferation; GO:0051006 positive regulation of lipoprotein lipase activity; GO:0006638 neutral lipid metabolic process; GO:0006950 response to stress; GO:0051270 regulation of cellular component movement; GO:0051917 regulation of fibrinolysis; GO:0016192 vesicle-mediated transport; GO:0030334 regulation of cell migration; GO:0071702 organic substance transport; GO:0010876 lipid localization; GO:0072376 protein activation cascade; GO:0032101 regulation of response to external stimulus; GO:0044238 primary metabolic process; GO:0033033 negative regulation of myeloid cell apoptotic process; GO:0072378 blood coagulation, fibrin clot formation; GO:0030195 negative regulation of blood coagulation; GO:0045055 regulated exocytosis; GO:0010596 negative regulation of endothelial cell migration; GO:0006641 triglyceride metabolic process; GO:0061041 regulation of wound healing; GO:0030336 negative regulation of cell migration; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:1903034 regulation of response to wounding; GO:0050819 negative regulation of coagulation; GO:0006887 exocytosis; GO:0051093 negative regulation of developmental process; GO:0046486 glycerolipid metabolic process; GO:0010633 negative regulation of epithelial cell migration; GO:0044699 single-organism process; GO:0051241 negative regulation of multicellular organismal process; GO:0033032 regulation of myeloid cell apoptotic process; GO:0016485 protein processing; GO:0051234 establishment of localization; GO:0009611 response to wounding; GO:0001937 negative regulation of endothelial cell proliferation; GO:0040013 negative regulation of locomotion; GO:0034197 triglyceride transport; GO:0032103 positive regulation of response to external stimulus; GO:0031639 plasminogen activation; GO:1900046 regulation of hemostasis; GO:0033036 macromolecule localization; GO:0006629 lipid metabolic process; GO:2000181 negative regulation of blood vessel morphogenesis; GO:0034392 negative regulation of smooth muscle cell apoptotic process; GO:0007597 blood coagulation, intrinsic pathway; GO:1903035 negative regulation of response to wounding; GO:0060193 positive regulation of lipase activity; GO:0050789 regulation of biological process; GO:0016525 negative regulation of angiogenesis; GO:0032940 secretion by cell; GO:0065009 regulation of molecular function; GO:0050680 negative regulation of epithelial cell proliferation; GO:0051271 negative regulation of cellular component movement; GO:2000026 regulation of multicellular organismal development; GO:0043069 negative regulation of programmed cell death; GO:0051918 negative regulation of fibrinolysis; GO:0050896 response to stimulus; GO:0007599 hemostasis; GO:0071704 organic substance metabolic process; GO:0043066 negative regulation of apoptotic process; GO:0006508 proteolysis; GO:0009987 cellular process; GO:0034196 acylglycerol transport; GO:0050878 regulation of body fluid levels; GO:1901342 regulation of vasculature development; GO:0050820 positive regulation of coagulation; GO:0048585 negative regulation of response to stimulus; GO:0048518 positive regulation of biological process; GO:0061045 negative regulation of wound healing; GO:0010656 negative regulation of muscle cell apoptotic process; GO:0043085 positive regulation of catalytic activity; GO:0050818 regulation of coagulation; GO:0042060 wound healing; GO:0022603 regulation of anatomical structure morphogenesis; GO:0010467 gene expression; GO:0040012 regulation of locomotion; GO:0051604 protein maturation; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0042827 platelet dense granule; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0034358 plasma lipoprotein particle; GO:0044433 cytoplasmic vesicle part; GO:0034385 triglyceride-rich plasma lipoprotein particle; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0034361 very-low-density lipoprotein particle; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0032994 protein-lipid complex; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1990777 lipoprotein particle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0042627 chylomicron; GO:0034364 high-density lipoprotein particle; GO:0005576 extracellular region; GO:0043226 organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0009986 cell surface; GO:0031089 platelet dense granule lumen; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0043167 ion binding; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0008201 heparin binding; GO:1901681 sulfur compound binding; GO:0097367 carbohydrate derivative binding; GO:0042802 identical protein binding; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0005543 phospholipid binding; GO:0008289 lipid binding; GO:0060229 lipase activator activity; GO:0043168 anion binding; GO:0001948 glycoprotein binding; GO:0005539 glycosaminoglycan binding; GO:0060230 lipoprotein lipase activator activity; GO:0008047 enzyme activator activity; ","K17305","APOH; beta-2-glycoprotein 1","hsa04979 Cholesterol metabolism - Homo sapiens (human); ","IPR000436; IPR015104; ","Sushi/SCR/CCP domain; Beta-2-glycoprotein-1 fifth domain; \r"]
["P02750","Leucine-rich alpha-2-glycoprotein OS=Homo sapiens OX=9606 GN=LRG1","LRG1",38.177,22.987,16.1,5,8,5,0.97,0.966,0.923,1.014,1.006,1.059,1.077,0.0302,"extracellular\r","GO:0045321 leukocyte activation; GO:0023051 regulation of signaling; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0051234 establishment of localization; GO:0090100 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0010646 regulation of cell communication; GO:0051240 positive regulation of multicellular organismal process; GO:0050678 regulation of epithelial cell proliferation; GO:1904018 positive regulation of vasculature development; GO:0050873 brown fat cell differentiation; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:0002443 leukocyte mediated immunity; GO:1903846 positive regulation of cellular response to transforming growth factor beta stimulus; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0090287 regulation of cellular response to growth factor stimulus; GO:0001938 positive regulation of endothelial cell proliferation; GO:0002444 myeloid leukocyte mediated immunity; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0032940 secretion by cell; GO:0048583 regulation of response to stimulus; GO:0045765 regulation of angiogenesis; GO:0045444 fat cell differentiation; GO:0043299 leukocyte degranulation; GO:0051094 positive regulation of developmental process; GO:2000026 regulation of multicellular organismal development; GO:0050794 regulation of cellular process; GO:0002283 neutrophil activation involved in immune response; GO:0042127 regulation of cell proliferation; GO:0002252 immune effector process; GO:0017015 regulation of transforming growth factor beta receptor signaling pathway; GO:0050896 response to stimulus; GO:0045766 positive regulation of angiogenesis; GO:0051239 regulation of multicellular organismal process; GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0030154 cell differentiation; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0023056 positive regulation of signaling; GO:0010647 positive regulation of cell communication; GO:0036230 granulocyte activation; GO:0001936 regulation of endothelial cell proliferation; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:0016192 vesicle-mediated transport; GO:1901342 regulation of vasculature development; GO:0002376 immune system process; GO:0043312 neutrophil degranulation; GO:0002263 cell activation involved in immune response; GO:0048518 positive regulation of biological process; GO:0002366 leukocyte activation involved in immune response; GO:1903844 regulation of cellular response to transforming growth factor beta stimulus; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0001775 cell activation; GO:0009967 positive regulation of signal transduction; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0006955 immune response; GO:0050793 regulation of developmental process; GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway; GO:0006887 exocytosis; GO:0065007 biological regulation; GO:0050679 positive regulation of epithelial cell proliferation; GO:0008284 positive regulation of cell proliferation; ","GO:0034774 secretory granule lumen; GO:0016020 membrane; GO:1904724 tertiary granule lumen; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0070820 tertiary granule; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0035580 specific granule lumen; GO:0042581 specific granule; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005102 receptor binding; GO:0005160 transforming growth factor beta receptor binding; GO:0005488 binding; GO:0005126 cytokine receptor binding; ",{"$nulls":3},"IPR000483; IPR032675; ","\"Cysteine-rich flanking region, C-terminal; Leucine-rich repeat domain, L domain-like; \"\r"]
["P02751","Fibronectin OS=Homo sapiens OX=9606 GN=FN1","FN1",262.62,323.31,30.1,54,90,54,1.021,0.972,1.018,1.008,1.014,0.991,1.001,0.962,"extracellular\r","GO:0044085 cellular component biogenesis; GO:0030335 positive regulation of cell migration; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0032989 cellular component morphogenesis; GO:0044237 cellular metabolic process; GO:0045927 positive regulation of growth; GO:0001558 regulation of cell growth; GO:0007492 endoderm development; GO:0048145 regulation of fibroblast proliferation; GO:0022610 biological adhesion; GO:0001525 angiogenesis; GO:0034446 substrate adhesion-dependent cell spreading; GO:0008152 metabolic process; GO:0048146 positive regulation of fibroblast proliferation; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0008360 regulation of cell shape; GO:0065003 macromolecular complex assembly; GO:0044093 positive regulation of molecular function; GO:0032535 regulation of cellular component size; GO:0007160 cell-matrix adhesion; GO:0007155 cell adhesion; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0009790 embryo development; GO:0048598 embryonic morphogenesis; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0051051 negative regulation of transport; GO:0007399 nervous system development; GO:0042325 regulation of phosphorylation; GO:0050709 negative regulation of protein secretion; GO:0051174 regulation of phosphorus metabolic process; GO:0030307 positive regulation of cell growth; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0031346 positive regulation of cell projection organization; GO:1903531 negative regulation of secretion by cell; GO:0045773 positive regulation of axon extension; GO:0044763 single-organism cellular process; GO:0050707 regulation of cytokine secretion; GO:0051272 positive regulation of cellular component movement; GO:0048870 cell motility; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0010811 positive regulation of cell-substrate adhesion; GO:0000902 cell morphogenesis; GO:0006810 transport; GO:0050900 leukocyte migration; GO:0051336 regulation of hydrolase activity; GO:0006953 acute-phase response; GO:2001202 negative regulation of transforming growth factor-beta secretion; GO:0050790 regulation of catalytic activity; GO:0002526 acute inflammatory response; GO:0048583 regulation of response to stimulus; GO:0098602 single organism cell adhesion; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051223 regulation of protein transport; GO:0006464 cellular protein modification process; GO:0051094 positive regulation of developmental process; GO:0010952 positive regulation of peptidase activity; GO:0010975 regulation of neuron projection development; GO:0050794 regulation of cellular process; GO:0072359 circulatory system development; GO:0044707 single-multicellular organism process; GO:0042127 regulation of cell proliferation; GO:0033622 integrin activation; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0018149 peptide cross-linking; GO:0002576 platelet degranulation; GO:2000147 positive regulation of cell motility; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0051239 regulation of multicellular organismal process; GO:0045597 positive regulation of cell differentiation; GO:0009653 anatomical structure morphogenesis; GO:0070372 regulation of ERK1 and ERK2 cascade; GO:1902578 single-organism localization; GO:0051345 positive regulation of hydrolase activity; GO:0050772 positive regulation of axonogenesis; GO:2000145 regulation of cell motility; GO:0043062 extracellular structure organization; GO:0010628 positive regulation of gene expression; GO:0032880 regulation of protein localization; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0006461 protein complex assembly; GO:1902531 regulation of intracellular signal transduction; GO:0045785 positive regulation of cell adhesion; GO:0006950 response to stress; GO:0051270 regulation of cellular component movement; GO:0051224 negative regulation of protein transport; GO:0048731 system development; GO:0051960 regulation of nervous system development; GO:0060284 regulation of cell development; GO:0016192 vesicle-mediated transport; GO:0030334 regulation of cell migration; GO:0002376 immune system process; GO:0072358 cardiovascular system development; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0030155 regulation of cell adhesion; GO:0050770 regulation of axonogenesis; GO:0045055 regulated exocytosis; GO:0051247 positive regulation of protein metabolic process; GO:0030516 regulation of axon extension; GO:0010976 positive regulation of neuron projection development; GO:0031325 positive regulation of cellular metabolic process; GO:0061387 regulation of extent of cell growth; GO:0006928 movement of cell or subcellular component; GO:0050769 positive regulation of neurogenesis; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:0010810 regulation of cell-substrate adhesion; GO:0043412 macromolecule modification; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0008284 positive regulation of cell proliferation; GO:0006887 exocytosis; GO:0045666 positive regulation of neuron differentiation; GO:0051674 localization of cell; GO:0001568 blood vessel development; GO:0040017 positive regulation of locomotion; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:0051241 negative regulation of multicellular organismal process; GO:0051046 regulation of secretion; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0001818 negative regulation of cytokine production; GO:0050710 negative regulation of cytokine secretion; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0009611 response to wounding; GO:0010646 regulation of cell communication; GO:0022607 cellular component assembly; GO:0009893 positive regulation of metabolic process; GO:0022617 extracellular matrix disassembly; GO:0048514 blood vessel morphogenesis; GO:0030198 extracellular matrix organization; GO:0010720 positive regulation of cell development; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0007044 cell-substrate junction assembly; GO:0048639 positive regulation of developmental growth; GO:0071822 protein complex subunit organization; GO:0009888 tissue development; GO:0001704 formation of primary germ layer; GO:2001201 regulation of transforming growth factor-beta secretion; GO:0051962 positive regulation of nervous system development; GO:0001944 vasculature development; GO:0048522 positive regulation of cellular process; GO:1903530 regulation of secretion by cell; GO:0051048 negative regulation of secretion; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0045664 regulation of neuron differentiation; GO:0032940 secretion by cell; GO:0006954 inflammatory response; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0006952 defense response; GO:0040011 locomotion; GO:0019220 regulation of phosphate metabolic process; GO:0052547 regulation of peptidase activity; GO:1904237 positive regulation of substrate-dependent cell migration, cell attachment to substrate; GO:0036211 protein modification process; GO:0070271 protein complex biogenesis; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0016477 cell migration; GO:0016043 cellular component organization; GO:0034329 cell junction assembly; GO:0040008 regulation of growth; GO:0060255 regulation of macromolecule metabolic process; GO:0010770 positive regulation of cell morphogenesis involved in differentiation; GO:0031344 regulation of cell projection organization; GO:0050896 response to stimulus; GO:0048638 regulation of developmental growth; GO:0070201 regulation of establishment of protein localization; GO:0048468 cell development; GO:0000904 cell morphogenesis involved in differentiation; GO:0071704 organic substance metabolic process; GO:0007369 gastrulation; GO:1904235 regulation of substrate-dependent cell migration, cell attachment to substrate; GO:0030154 cell differentiation; GO:0045862 positive regulation of proteolysis; GO:0008361 regulation of cell size; GO:0043408 regulation of MAPK cascade; GO:0050708 regulation of protein secretion; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0001706 endoderm formation; GO:0035987 endodermal cell differentiation; GO:0051049 regulation of transport; GO:0001932 regulation of protein phosphorylation; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0043933 macromolecular complex subunit organization; GO:0042060 wound healing; GO:0034330 cell junction organization; GO:0031589 cell-substrate adhesion; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0001817 regulation of cytokine production; GO:0090066 regulation of anatomical structure size; GO:0022411 cellular component disassembly; GO:1904950 negative regulation of establishment of protein localization; GO:0051128 regulation of cellular component organization; GO:0007161 calcium-independent cell-matrix adhesion; GO:0040012 regulation of locomotion; GO:0022604 regulation of cell morphogenesis; GO:0050767 regulation of neurogenesis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0016324 apical plasma membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044420 extracellular matrix component; GO:0044422 organelle part; GO:0005604 basement membrane; GO:0031974 membrane-enclosed lumen; GO:0005605 basal lamina; GO:0070062 extracellular exosome; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0098590 plasma membrane region; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0045177 apical part of cell; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0005577 fibrinogen complex; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0031012 extracellular matrix; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0072562 blood microparticle; GO:0060205 cytoplasmic vesicle lumen; GO:0044459 plasma membrane part; GO:0005793 endoplasmic reticulum-Golgi intermediate compartment; GO:0005578 proteinaceous extracellular matrix; GO:0031093 platelet alpha granule lumen; GO:0031091 platelet alpha granule; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005102 receptor binding; GO:0043167 ion binding; GO:0044877 macromolecular complex binding; GO:0061134 peptidase regulator activity; GO:0016504 peptidase activator activity; GO:0005515 protein binding; GO:0005178 integrin binding; GO:0008201 heparin binding; GO:0098772 molecular function regulator; GO:1901681 sulfur compound binding; GO:0002020 protease binding; GO:0050839 cell adhesion molecule binding; GO:0097367 carbohydrate derivative binding; GO:0042802 identical protein binding; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0005518 collagen binding; GO:0043168 anion binding; GO:0005539 glycosaminoglycan binding; GO:0019899 enzyme binding; GO:0008047 enzyme activator activity; GO:0032403 protein complex binding; ","K05717","FN1; fibronectin 1","hsa05100 Bacterial invasion of epithelial cells - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa04933 AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa05146 Amoebiasis - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa05222 Small cell lung cancer - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa04512 ECM-receptor interaction - Homo sapiens (human); ","IPR000083; IPR013783; IPR013806; IPR003961; IPR000562; ","\"Fibronectin, type I; Immunoglobulin-like fold; Kringle-like fold; Fibronectin type III; Fibronectin, type II, collagen-binding; \"\r"]
["P02753","Retinol-binding protein 4 OS=Homo sapiens OX=9606 GN=RBP4","RBP4",23.01,32.527,29.9,5,11,5,1.023,1.012,0.962,0.968,1.04,1.022,1.011,0.725,"extracellular\r","GO:0065008 regulation of biological quality; GO:0007586 digestion; GO:0060042 retina morphogenesis in camera-type eye; GO:0007601 visual perception; GO:0022414 reproductive process; GO:0006066 alcohol metabolic process; GO:0030323 respiratory tube development; GO:0043009 chordate embryonic development; GO:0050796 regulation of insulin secretion; GO:0042593 glucose homeostasis; GO:1901862 negative regulation of muscle tissue development; GO:0044255 cellular lipid metabolic process; GO:0002793 positive regulation of peptide secretion; GO:0044237 cellular metabolic process; GO:0050877 neurological system process; GO:0008285 negative regulation of cell proliferation; GO:0006006 glucose metabolic process; GO:0008152 metabolic process; GO:0006094 gluconeogenesis; GO:0007507 heart development; GO:0048562 embryonic organ morphogenesis; GO:0045843 negative regulation of striated muscle tissue development; GO:0032879 regulation of localization; GO:0060343 trabecula formation; GO:0044702 single organism reproductive process; GO:0048706 embryonic skeletal system development; GO:0009790 embryo development; GO:0090596 sensory organ morphogenesis; GO:0048598 embryonic morphogenesis; GO:0044765 single-organism transport; GO:0003006 developmental process involved in reproduction; GO:0060068 vagina development; GO:0006869 lipid transport; GO:0035112 genitalia morphogenesis; GO:0048592 eye morphogenesis; GO:0002639 positive regulation of immunoglobulin production; GO:0060537 muscle tissue development; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0005975 carbohydrate metabolic process; GO:0061383 trabecula morphogenesis; GO:0032501 multicellular organismal process; GO:0034754 cellular hormone metabolic process; GO:0048807 female genitalia morphogenesis; GO:0006810 transport; GO:0048635 negative regulation of muscle organ development; GO:0048513 animal organ development; GO:0046883 regulation of hormone secretion; GO:0032526 response to retinoic acid; GO:0044710 single-organism metabolic process; GO:0050714 positive regulation of protein secretion; GO:0010817 regulation of hormone levels; GO:0009887 animal organ morphogenesis; GO:0002682 regulation of immune system process; GO:0051223 regulation of protein transport; GO:0016101 diterpenoid metabolic process; GO:0051023 regulation of immunoglobulin secretion; GO:0051047 positive regulation of secretion; GO:0050794 regulation of cellular process; GO:0000003 reproduction; GO:0072359 circulatory system development; GO:0044707 single-multicellular organism process; GO:1901615 organic hydroxy compound metabolic process; GO:0042127 regulation of cell proliferation; GO:0034633 retinol transport; GO:1901700 response to oxygen-containing compound; GO:0046364 monosaccharide biosynthetic process; GO:0046864 isoprenoid transport; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0055022 negative regulation of cardiac muscle tissue growth; GO:0090277 positive regulation of peptide hormone secretion; GO:0060249 anatomical structure homeostasis; GO:0051239 regulation of multicellular organismal process; GO:0061384 heart trabecula morphogenesis; GO:0009653 anatomical structure morphogenesis; GO:0001654 eye development; GO:1902578 single-organism localization; GO:0060541 respiratory system development; GO:0007548 sex differentiation; GO:0033500 carbohydrate homeostasis; GO:0032880 regulation of protein localization; GO:0007275 multicellular organism development; GO:0048806 genitalia development; GO:0061458 reproductive system development; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0048878 chemical homeostasis; GO:0090087 regulation of peptide transport; GO:0006720 isoprenoid metabolic process; GO:0044711 single-organism biosynthetic process; GO:0048731 system development; GO:0071702 organic substance transport; GO:0010876 lipid localization; GO:0097305 response to alcohol; GO:0046621 negative regulation of organ growth; GO:0010033 response to organic substance; GO:0003206 cardiac chamber morphogenesis; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0060043 regulation of cardiac muscle cell proliferation; GO:1904951 positive regulation of establishment of protein localization; GO:0060059 embryonic retina morphogenesis in camera-type eye; GO:0046887 positive regulation of hormone secretion; GO:0044283 small molecule biosynthetic process; GO:0007423 sensory organ development; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0019318 hexose metabolic process; GO:0046620 regulation of organ growth; GO:0002702 positive regulation of production of molecular mediator of immune response; GO:0051093 negative regulation of developmental process; GO:0055021 regulation of cardiac muscle tissue growth; GO:0001101 response to acid chemical; GO:0015850 organic hydroxy compound transport; GO:0060065 uterus development; GO:0019319 hexose biosynthetic process; GO:0048640 negative regulation of developmental growth; GO:0060420 regulation of heart growth; GO:0023051 regulation of signaling; GO:0048634 regulation of muscle organ development; GO:0051046 regulation of secretion; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0046660 female sex differentiation; GO:0048871 multicellular organismal homeostasis; GO:0051234 establishment of localization; GO:0030277 maintenance of gastrointestinal epithelium; GO:0046865 terpenoid transport; GO:0010646 regulation of cell communication; GO:0034308 primary alcohol metabolic process; GO:0033036 macromolecule localization; GO:0002697 regulation of immune effector process; GO:0060157 urinary bladder development; GO:0006629 lipid metabolic process; GO:0030324 lung development; GO:0055024 regulation of cardiac muscle tissue development; GO:0032502 developmental process; GO:0035295 tube development; GO:0045926 negative regulation of growth; GO:0042445 hormone metabolic process; GO:0007600 sensory perception; GO:0009888 tissue development; GO:0003007 heart morphogenesis; GO:0048608 reproductive structure development; GO:0048522 positive regulation of cellular process; GO:0002700 regulation of production of molecular mediator of immune response; GO:0051024 positive regulation of immunoglobulin secretion; GO:1903530 regulation of secretion by cell; GO:0051050 positive regulation of transport; GO:0044723 single-organism carbohydrate metabolic process; GO:0001655 urogenital system development; GO:0016202 regulation of striated muscle tissue development; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0061117 negative regulation of heart growth; GO:1903532 positive regulation of secretion by cell; GO:0001894 tissue homeostasis; GO:0048856 anatomical structure development; GO:0051222 positive regulation of protein transport; GO:0001501 skeletal system development; GO:2000026 regulation of multicellular organismal development; GO:0030540 female genitalia development; GO:0014706 striated muscle tissue development; GO:0060044 negative regulation of cardiac muscle cell proliferation; GO:0043010 camera-type eye development; GO:0016051 carbohydrate biosynthetic process; GO:0040008 regulation of growth; GO:0048738 cardiac muscle tissue development; GO:0048568 embryonic organ development; GO:0045471 response to ethanol; GO:0072001 renal system development; GO:0048638 regulation of developmental growth; GO:0050896 response to stimulus; GO:0070201 regulation of establishment of protein localization; GO:0071704 organic substance metabolic process; GO:0033993 response to lipid; GO:0042592 homeostatic process; GO:0002791 regulation of peptide secretion; GO:0023056 positive regulation of signaling; GO:0005996 monosaccharide metabolic process; GO:0001523 retinoid metabolic process; GO:0010647 positive regulation of cell communication; GO:0050708 regulation of protein secretion; GO:0010669 epithelial structure maintenance; GO:0009987 cellular process; GO:0055026 negative regulation of cardiac muscle tissue development; GO:0060041 retina development in camera-type eye; GO:0032024 positive regulation of insulin secretion; GO:0003008 system process; GO:0051049 regulation of transport; GO:0002699 positive regulation of immune effector process; GO:1901861 regulation of muscle tissue development; GO:0009792 embryo development ending in birth or egg hatching; GO:0048593 camera-type eye morphogenesis; GO:0050953 sensory perception of light stimulus; GO:0048518 positive regulation of biological process; GO:0003205 cardiac chamber development; GO:0042572 retinol metabolic process; GO:0044767 single-organism developmental process; GO:0002684 positive regulation of immune system process; GO:0002637 regulation of immunoglobulin production; GO:0022600 digestive system process; GO:0090276 regulation of peptide hormone secretion; GO:0006721 terpenoid metabolic process; GO:0060347 heart trabecula formation; GO:0065007 biological regulation; ","GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0019842 vitamin binding; GO:0046982 protein heterodimerization activity; GO:0019841 retinol binding; GO:0046983 protein dimerization activity; GO:0005501 retinoid binding; GO:0005319 lipid transporter activity; GO:0022892 substrate-specific transporter activity; GO:0051183 vitamin transporter activity; GO:0005515 protein binding; GO:0019840 isoprenoid binding; GO:0034632 retinol transporter activity; GO:0005488 binding; GO:0043178 alcohol binding; GO:0008289 lipid binding; GO:0016918 retinal binding; GO:0036094 small molecule binding; GO:0005215 transporter activity; ","K18271",null,null,"IPR000566; IPR012674; IPR011038; ","Lipocalin/cytosolic fatty-acid binding domain; Calycin; Calycin-like; \r"]
["P02760","Protein AMBP OS=Homo sapiens OX=9606 GN=AMBP","AMBP",38.999,127.1,41.2,12,25,12,1.085,1.049,1.059,0.944,0.904,0.933,0.871,1.08E-3,"extracellular\r","GO:0032872 regulation of stress-activated MAPK cascade; GO:0009968 negative regulation of signal transduction; GO:0022414 reproductive process; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0031400 negative regulation of protein modification process; GO:0051234 establishment of localization; GO:0022610 biological adhesion; GO:0010466 negative regulation of peptidase activity; GO:0008152 metabolic process; GO:0010646 regulation of cell communication; GO:0070302 regulation of stress-activated protein kinase signaling cascade; GO:0051187 cofactor catabolic process; GO:0033015 tetrapyrrole catabolic process; GO:0018298 protein-chromophore linkage; GO:0044706 multi-multicellular organism process; GO:0032873 negative regulation of stress-activated MAPK cascade; GO:0070303 negative regulation of stress-activated protein kinase signaling cascade; GO:0007155 cell adhesion; GO:1901361 organic cyclic compound catabolic process; GO:0050777 negative regulation of immune response; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0046328 regulation of JNK cascade; GO:0052548 regulation of endopeptidase activity; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0046329 negative regulation of JNK cascade; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0051186 cofactor metabolic process; GO:0006810 transport; GO:0002683 negative regulation of immune system process; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0046149 pigment catabolic process; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0080135 regulation of cellular response to stress; GO:1902532 negative regulation of intracellular signal transduction; GO:0006787 porphyrin-containing compound catabolic process; GO:0051336 regulation of hydrolase activity; GO:0030163 protein catabolic process; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0033013 tetrapyrrole metabolic process; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0002682 regulation of immune system process; GO:0006464 cellular protein modification process; GO:0044092 negative regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0036211 protein modification process; GO:0052547 regulation of peptidase activity; GO:0000003 reproduction; GO:0050794 regulation of cellular process; GO:0010951 negative regulation of endopeptidase activity; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0042167 heme catabolic process; GO:0080134 regulation of response to stress; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0042168 heme metabolic process; GO:0051346 negative regulation of hydrolase activity; GO:0071704 organic substance metabolic process; GO:0007565 female pregnancy; GO:0044270 cellular nitrogen compound catabolic process; GO:0006778 porphyrin-containing compound metabolic process; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0046483 heterocycle metabolic process; GO:0043408 regulation of MAPK cascade; GO:0016032 viral process; GO:0042326 negative regulation of phosphorylation; GO:0044248 cellular catabolic process; GO:0001933 negative regulation of protein phosphorylation; GO:0034641 cellular nitrogen compound metabolic process; GO:0006898 receptor-mediated endocytosis; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:0045861 negative regulation of proteolysis; GO:1902531 regulation of intracellular signal transduction; GO:0042440 pigment metabolic process; GO:0044712 single-organism catabolic process; GO:0016192 vesicle-mediated transport; GO:0001932 regulation of protein phosphorylation; GO:0006807 nitrogen compound metabolic process; GO:0048585 negative regulation of response to stimulus; GO:0030162 regulation of proteolysis; GO:0006897 endocytosis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901565 organonitrogen compound catabolic process; GO:0051246 regulation of protein metabolic process; GO:0009057 macromolecule catabolic process; GO:0044703 multi-organism reproductive process; GO:0010563 negative regulation of phosphorus metabolic process; GO:0043409 negative regulation of MAPK cascade; GO:0051248 negative regulation of protein metabolic process; GO:0051179 localization; GO:0043412 macromolecule modification; GO:0009056 catabolic process; GO:0045936 negative regulation of phosphate metabolic process; GO:0065007 biological regulation; GO:1901564 organonitrogen compound metabolic process; GO:0046700 heterocycle catabolic process; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0072562 blood microparticle; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0009986 cell surface; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0008200 ion channel inhibitor activity; GO:0019865 immunoglobulin binding; GO:0046983 protein dimerization activity; GO:0044877 macromolecular complex binding; GO:0061134 peptidase regulator activity; GO:0046904 calcium oxalate binding; GO:0099106 ion channel regulator activity; GO:0005515 protein binding; GO:0005246 calcium channel regulator activity; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0004866 endopeptidase inhibitor activity; GO:0016248 channel inhibitor activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0020037 heme binding; GO:0019855 calcium channel inhibitor activity; GO:0004867 serine-type endopeptidase inhibitor activity; GO:0042802 identical protein binding; GO:0019862 IgA binding; GO:0030234 enzyme regulator activity; GO:0016247 channel regulator activity; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0030414 peptidase inhibitor activity; GO:0061135 endopeptidase regulator activity; GO:0046906 tetrapyrrole binding; GO:0036094 small molecule binding; GO:0032403 protein complex binding; ",{"$nulls":3},"IPR000566; IPR012674; IPR011038; IPR002223; ","Lipocalin/cytosolic fatty-acid binding domain; Calycin; Calycin-like; Pancreatic trypsin inhibitor Kunitz domain; \r"]
["P02763","Alpha-1-acid glycoprotein 1 OS=Homo sapiens OX=9606 GN=ORM1","ORM1",23.511,39.643,26.4,4,7,4,0.896,1.006,0.933,1.043,1.042,1.092,1.121,0.037,"extracellular\r","GO:1903555 regulation of tumor necrosis factor superfamily cytokine production; GO:0045321 leukocyte activation; GO:0002283 neutrophil activation involved in immune response; GO:0032715 negative regulation of interleukin-6 production; GO:0002252 immune effector process; GO:0032680 regulation of tumor necrosis factor production; GO:0002576 platelet degranulation; GO:0044699 single-organism process; GO:0051241 negative regulation of multicellular organismal process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0001818 negative regulation of cytokine production; GO:0051239 regulation of multicellular organismal process; GO:0051234 establishment of localization; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:1903556 negative regulation of tumor necrosis factor superfamily cytokine production; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0002443 leukocyte mediated immunity; GO:0006950 response to stress; GO:0032720 negative regulation of tumor necrosis factor production; GO:0002446 neutrophil mediated immunity; GO:0016192 vesicle-mediated transport; GO:0032675 regulation of interleukin-6 production; GO:0044763 single-organism cellular process; GO:0002376 immune system process; GO:0043312 neutrophil degranulation; GO:0002263 cell activation involved in immune response; GO:0002444 myeloid leukocyte mediated immunity; GO:0002366 leukocyte activation involved in immune response; GO:0006810 transport; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0050789 regulation of biological process; GO:0006953 acute-phase response; GO:0002526 acute inflammatory response; GO:0032940 secretion by cell; GO:0006954 inflammatory response; GO:0001775 cell activation; GO:0001817 regulation of cytokine production; GO:0002682 regulation of immune system process; GO:0006952 defense response; GO:0043299 leukocyte degranulation; GO:0006955 immune response; GO:0051179 localization; GO:0065007 biological regulation; GO:0006887 exocytosis; ","GO:0034774 secretory granule lumen; GO:1904724 tertiary granule lumen; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0070820 tertiary granule; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0043226 organelle; GO:0072562 blood microparticle; GO:0060205 cytoplasmic vesicle lumen; GO:0035580 specific granule lumen; GO:0042581 specific granule; GO:0031093 platelet alpha granule lumen; GO:0031091 platelet alpha granule; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ","K17308",null,null,"IPR000566; IPR012674; IPR011038; ","Lipocalin/cytosolic fatty-acid binding domain; Calycin; Calycin-like; \r"]
["P02765","Alpha-2-HS-glycoprotein OS=Homo sapiens OX=9606 GN=AHSG","AHSG",39.324,152.35,24.3,8,28,8,1.037,1.066,1.079,0.931,0.965,0.942,0.892,1.92E-3,"extracellular\r","GO:0060627 regulation of vesicle-mediated transport; GO:0051093 negative regulation of developmental process; GO:0045321 leukocyte activation; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0051241 negative regulation of multicellular organismal process; GO:0030500 regulation of bone mineralization; GO:0031347 regulation of defense response; GO:0070167 regulation of biomineral tissue development; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0010466 negative regulation of peptidase activity; GO:0010646 regulation of cell communication; GO:0032879 regulation of localization; GO:0050764 regulation of phagocytosis; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0032502 developmental process; GO:0052548 regulation of endopeptidase activity; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0002443 leukocyte mediated immunity; GO:0080090 regulation of primary metabolic process; GO:0001503 ossification; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0070168 negative regulation of biomineral tissue development; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0006907 pinocytosis; GO:0032501 multicellular organismal process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0051050 positive regulation of transport; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0006953 acute-phase response; GO:0051336 regulation of hydrolase activity; GO:0002526 acute inflammatory response; GO:0032940 secretion by cell; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0006954 inflammatory response; GO:0048583 regulation of response to stimulus; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0006952 defense response; GO:0043299 leukocyte degranulation; GO:0052547 regulation of peptidase activity; GO:0048856 anatomical structure development; GO:0001501 skeletal system development; GO:2000026 regulation of multicellular organismal development; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:1900077 negative regulation of cellular response to insulin stimulus; GO:0010951 negative regulation of endopeptidase activity; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0045807 positive regulation of endocytosis; GO:0002576 platelet degranulation; GO:0046627 negative regulation of insulin receptor signaling pathway; GO:1900076 regulation of cellular response to insulin stimulus; GO:0080134 regulation of response to stress; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0051346 negative regulation of hydrolase activity; GO:0051239 regulation of multicellular organismal process; GO:0023057 negative regulation of signaling; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0010648 negative regulation of cell communication; GO:0042326 negative regulation of phosphorylation; GO:0007275 multicellular organism development; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0009966 regulation of signal transduction; GO:0045861 negative regulation of proteolysis; GO:0030502 negative regulation of bone mineralization; GO:0030100 regulation of endocytosis; GO:0006950 response to stress; GO:0048731 system development; GO:0051049 regulation of transport; GO:0016192 vesicle-mediated transport; GO:0050766 positive regulation of phagocytosis; GO:0032101 regulation of response to external stimulus; GO:0002376 immune system process; GO:0030162 regulation of proteolysis; GO:0048585 negative regulation of response to stimulus; GO:0006897 endocytosis; GO:0043312 neutrophil degranulation; GO:0002263 cell activation involved in immune response; GO:0009892 negative regulation of metabolic process; GO:0048518 positive regulation of biological process; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0046626 regulation of insulin receptor signaling pathway; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0010563 negative regulation of phosphorus metabolic process; GO:0030278 regulation of ossification; GO:0050727 regulation of inflammatory response; GO:0001775 cell activation; GO:0051248 negative regulation of protein metabolic process; GO:0030279 negative regulation of ossification; GO:0051128 regulation of cellular component organization; GO:0006955 immune response; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0045936 negative regulation of phosphate metabolic process; GO:0006887 exocytosis; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031012 extracellular matrix; GO:0072562 blood microparticle; GO:0060205 cytoplasmic vesicle lumen; GO:0031093 platelet alpha granule lumen; GO:0031091 platelet alpha granule; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0030234 enzyme regulator activity; GO:0019210 kinase inhibitor activity; GO:0030414 peptidase inhibitor activity; GO:0061134 peptidase regulator activity; GO:0061135 endopeptidase regulator activity; GO:0019207 kinase regulator activity; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0004866 endopeptidase inhibitor activity; GO:0004869 cysteine-type endopeptidase inhibitor activity; ",{"$nulls":3},"IPR000010; IPR025760; ","Cystatin domain; Fetuin-A-type cystatin domain; \r"]
["P02766","Transthyretin OS=Homo sapiens OX=9606 GN=TTR","TTR",15.887,130.6,63.9,6,18,6,1.055,1.033,1.028,1.012,0.976,0.951,0.943,0.0407,"extracellular\r","GO:0065008 regulation of biological quality; GO:0009914 hormone transport; GO:0072337 modified amino acid transport; GO:0045321 leukocyte activation; GO:0006066 alcohol metabolic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0030198 extracellular matrix organization; GO:0034308 primary alcohol metabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0006629 lipid metabolic process; GO:0002274 myeloid leukocyte activation; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0042445 hormone metabolic process; GO:0002443 leukocyte mediated immunity; GO:0044281 small molecule metabolic process; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0070327 thyroid hormone transport; GO:0002444 myeloid leukocyte mediated immunity; GO:0034754 cellular hormone metabolic process; GO:0006810 transport; GO:0044710 single-organism metabolic process; GO:0032940 secretion by cell; GO:0044260 cellular macromolecule metabolic process; GO:0010817 regulation of hormone levels; GO:0016101 diterpenoid metabolic process; GO:0043299 leukocyte degranulation; GO:0016043 cellular component organization; GO:0002283 neutrophil activation involved in immune response; GO:1901615 organic hydroxy compound metabolic process; GO:0002252 immune effector process; GO:0044267 cellular protein metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0043062 extracellular structure organization; GO:0001523 retinoid metabolic process; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0006720 isoprenoid metabolic process; GO:0016192 vesicle-mediated transport; GO:0071702 organic substance transport; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:0043312 neutrophil degranulation; GO:0002263 cell activation involved in immune response; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0042572 retinol metabolic process; GO:0001775 cell activation; GO:0006721 terpenoid metabolic process; GO:0051179 localization; GO:0006955 immune response; GO:0071705 nitrogen compound transport; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:0006887 exocytosis; ","GO:0034774 secretory granule lumen; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0042582 azurophil granule; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0042802 identical protein binding; GO:0046982 protein heterodimerization activity; GO:0005102 receptor binding; GO:0042562 hormone binding; GO:0005488 binding; GO:0005179 hormone activity; GO:0046983 protein dimerization activity; GO:0070324 thyroid hormone binding; GO:0005515 protein binding; ","K20731","TTR; transthyretin","hsa04918 Thyroid hormone synthesis - Homo sapiens (human); ","IPR023416; ","\"Transthyretin/hydroxyisourate hydrolase, superfamily; \"\r"]
["P02774","Vitamin D-binding protein OS=Homo sapiens OX=9606 GN=GC","GC",52.963,323.31,58,27,71,27,1.076,1.059,1.092,0.927,0.926,0.938,0.865,1.2E-4,"extracellular\r","GO:1901615 organic hydroxy compound metabolic process; GO:0044281 small molecule metabolic process; GO:0008202 steroid metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0044699 single-organism process; GO:0044238 primary metabolic process; GO:0071704 organic substance metabolic process; GO:0051234 establishment of localization; GO:0006810 transport; GO:0006775 fat-soluble vitamin metabolic process; GO:0006766 vitamin metabolic process; GO:0008152 metabolic process; GO:1902578 single-organism localization; GO:0044710 single-organism metabolic process; GO:0051180 vitamin transport; GO:0051179 localization; GO:0042359 vitamin D metabolic process; GO:0006629 lipid metabolic process; GO:0044765 single-organism transport; ","GO:0043229 intracellular organelle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0043202 lysosomal lumen; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0072562 blood microparticle; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0044437 vacuolar part; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0005773 vacuole; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0000323 lytic vacuole; ","GO:0097159 organic cyclic compound binding; GO:1902118 calcidiol binding; GO:1902271 D3 vitamins binding; GO:0008092 cytoskeletal protein binding; GO:0019842 vitamin binding; GO:0005488 binding; GO:0003779 actin binding; GO:0008289 lipid binding; GO:0005499 vitamin D binding; GO:0051183 vitamin transporter activity; GO:0005515 protein binding; GO:0005496 steroid binding; GO:0005215 transporter activity; GO:0036094 small molecule binding; ","K12258",null,null,"IPR020858; IPR014760; IPR015247; ","\"Serum albumin-like; Serum albumin, N-terminal; Vitamin D binding protein, domain III; \"\r"]
["P02786","Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC","TFRC",84.87,34.651,13.6,9,11,9,0.925,1.011,0.897,1.037,1.09,1.052,1.122,0.0401,"plasma membrane\r","GO:0044409 entry into host; GO:0002694 regulation of leukocyte activation; GO:0045191 regulation of isotype switching; GO:0065008 regulation of biological quality; GO:0032944 regulation of mononuclear cell proliferation; GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0030888 regulation of B cell proliferation; GO:0000041 transition metal ion transport; GO:0008152 metabolic process; GO:0032946 positive regulation of mononuclear cell proliferation; GO:0051240 positive regulation of multicellular organismal process; GO:0055065 metal ion homeostasis; GO:0043170 macromolecule metabolic process; GO:0008104 protein localization; GO:0044419 interspecies interaction between organisms; GO:0000018 regulation of DNA recombination; GO:0046718 viral entry into host cell; GO:0044765 single-organism transport; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0051054 positive regulation of DNA metabolic process; GO:0002639 positive regulation of immunoglobulin production; GO:0050864 regulation of B cell activation; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0050670 regulation of lymphocyte proliferation; GO:0002520 immune system development; GO:0031323 regulation of cellular metabolic process; GO:0033572 transferrin transport; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0046916 cellular transition metal ion homeostasis; GO:0006810 transport; GO:0002889 regulation of immunoglobulin mediated immune response; GO:0048513 animal organ development; GO:0044710 single-organism metabolic process; GO:0045780 positive regulation of bone resorption; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0002682 regulation of immune system process; GO:0002821 positive regulation of adaptive immune response; GO:0051094 positive regulation of developmental process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0055076 transition metal ion homeostasis; GO:0030316 osteoclast differentiation; GO:0042127 regulation of cell proliferation; GO:0030001 metal ion transport; GO:0051806 entry into cell of other organism involved in symbiotic interaction; GO:0030890 positive regulation of B cell proliferation; GO:0055072 iron ion homeostasis; GO:0032844 regulation of homeostatic process; GO:0046850 regulation of bone remodeling; GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0051239 regulation of multicellular organismal process; GO:0042493 response to drug; GO:0050867 positive regulation of cell activation; GO:1902578 single-organism localization; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:0051171 regulation of nitrogen compound metabolic process; GO:0006898 receptor-mediated endocytosis; GO:0007275 multicellular organism development; GO:0050778 positive regulation of immune response; GO:0048878 chemical homeostasis; GO:0045785 positive regulation of cell adhesion; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0071702 organic substance transport; GO:0002376 immune system process; GO:1903039 positive regulation of leukocyte cell-cell adhesion; GO:0030155 regulation of cell adhesion; GO:0045184 establishment of protein localization; GO:0072512 trivalent inorganic cation transport; GO:0002696 positive regulation of leukocyte activation; GO:0006873 cellular ion homeostasis; GO:0006811 ion transport; GO:0050870 positive regulation of T cell activation; GO:0061024 membrane organization; GO:0031325 positive regulation of cellular metabolic process; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0008284 positive regulation of cell proliferation; GO:0050863 regulation of T cell activation; GO:0002702 positive regulation of production of molecular mediator of immune response; GO:0031623 receptor internalization; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0034103 regulation of tissue remodeling; GO:0044764 multi-organism cellular process; GO:0051249 regulation of lymphocyte activation; GO:0051234 establishment of localization; GO:0050671 positive regulation of lymphocyte proliferation; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0032846 positive regulation of homeostatic process; GO:0002819 regulation of adaptive immune response; GO:0070663 regulation of leukocyte proliferation; GO:0033036 macromolecule localization; GO:0002697 regulation of immune effector process; GO:0002708 positive regulation of lymphocyte mediated immunity; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0043112 receptor metabolic process; GO:0050801 ion homeostasis; GO:0015682 ferric iron transport; GO:0002521 leukocyte differentiation; GO:0098771 inorganic ion homeostasis; GO:0019725 cellular homeostasis; GO:0048522 positive regulation of cellular process; GO:0002700 regulation of production of molecular mediator of immune response; GO:0051251 positive regulation of lymphocyte activation; GO:0097286 iron ion import; GO:0030260 entry into host cell; GO:0042221 response to chemical; GO:0050865 regulation of cell activation; GO:0050789 regulation of biological process; GO:0051052 regulation of DNA metabolic process; GO:0002705 positive regulation of leukocyte mediated immunity; GO:0051828 entry into other organism involved in symbiotic interaction; GO:0019222 regulation of metabolic process; GO:0048856 anatomical structure development; GO:0002891 positive regulation of immunoglobulin mediated immune response; GO:2000026 regulation of multicellular organismal development; GO:0006879 cellular iron ion homeostasis; GO:0016043 cellular component organization; GO:0035690 cellular response to drug; GO:0042102 positive regulation of T cell proliferation; GO:0060255 regulation of macromolecule metabolic process; GO:0030003 cellular cation homeostasis; GO:0019058 viral life cycle; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0006826 iron ion transport; GO:0045124 regulation of bone resorption; GO:0050896 response to stimulus; GO:0002706 regulation of lymphocyte mediated immunity; GO:0055082 cellular chemical homeostasis; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:0055080 cation homeostasis; GO:0050871 positive regulation of B cell activation; GO:0006812 cation transport; GO:0016032 viral process; GO:0002714 positive regulation of B cell mediated immunity; GO:0009987 cellular process; GO:0034105 positive regulation of tissue remodeling; GO:0030099 myeloid cell differentiation; GO:0022409 positive regulation of cell-cell adhesion; GO:0002699 positive regulation of immune effector process; GO:0046852 positive regulation of bone remodeling; GO:0002712 regulation of B cell mediated immunity; GO:0042129 regulation of T cell proliferation; GO:0006897 endocytosis; GO:0051701 interaction with host; GO:0048518 positive regulation of biological process; GO:0048534 hematopoietic or lymphoid organ development; GO:0030097 hemopoiesis; GO:0022407 regulation of cell-cell adhesion; GO:0002703 regulation of leukocyte mediated immunity; GO:0070665 positive regulation of leukocyte proliferation; GO:0045830 positive regulation of isotype switching; GO:0044767 single-organism developmental process; GO:0002573 myeloid leukocyte differentiation; GO:0002637 regulation of immunoglobulin production; GO:0002684 positive regulation of immune system process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0006875 cellular metal ion homeostasis; GO:0045911 positive regulation of DNA recombination; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016323 basolateral plasma membrane; GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0009897 external side of plasma membrane; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0030662 coated vesicle membrane; GO:0048770 pigment granule; GO:0055037 recycling endosome; GO:0070062 extracellular exosome; GO:0098590 plasma membrane region; GO:0030136 clathrin-coated vesicle; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0098589 membrane region; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0098552 side of membrane; GO:1990712 HFE-transferrin receptor complex; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0031226 intrinsic component of plasma membrane; GO:0098588 bounding membrane of organelle; GO:0042470 melanosome; GO:0044446 intracellular organelle part; GO:0098802 plasma membrane receptor complex; GO:0043235 receptor complex; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0030665 clathrin-coated vesicle membrane; GO:0030135 coated vesicle; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0072562 blood microparticle; GO:0044459 plasma membrane part; GO:0009986 cell surface; GO:0005905 clathrin-coated pit; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0015399 primary active transmembrane transporter activity; GO:0046983 protein dimerization activity; GO:0022892 substrate-specific transporter activity; GO:0008320 protein transmembrane transporter activity; GO:0038024 cargo receptor activity; GO:0005515 protein binding; GO:0004998 transferrin receptor activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0046873 metal ion transmembrane transporter activity; GO:0042802 identical protein binding; GO:0005488 binding; GO:0022890 inorganic cation transmembrane transporter activity; GO:0005215 transporter activity; GO:0022804 active transmembrane transporter activity; GO:0033570 transferrin transmembrane transporter activity; GO:0003723 RNA binding; GO:0008565 protein transporter activity; GO:0015075 ion transmembrane transporter activity; GO:0022884 macromolecule transmembrane transporter activity; GO:0003725 double-stranded RNA binding; GO:0046915 transition metal ion transmembrane transporter activity; GO:0001618 virus receptor activity; GO:0072510 trivalent inorganic cation transmembrane transporter activity; GO:0015091 ferric iron transmembrane transporter activity; GO:0097367 carbohydrate derivative binding; GO:0060089 molecular transducer activity; GO:0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity; GO:0004872 receptor activity; GO:0042803 protein homodimerization activity; GO:0005381 iron ion transmembrane transporter activity; GO:0003676 nucleic acid binding; GO:0001948 glycoprotein binding; GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity; GO:0008324 cation transmembrane transporter activity; GO:0022857 transmembrane transporter activity; ","K06503","TFRC; transferrin receptor","hsa04144 Endocytosis - Homo sapiens (human); hsa04066 HIF-1 signaling pathway - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); hsa04640 Hematopoietic cell lineage - Homo sapiens (human); hsa04216 Ferroptosis - Homo sapiens (human); ","IPR003137; IPR007484; IPR007365; ","\"PA domain; Peptidase M28; Transferrin receptor-like, dimerisation domain; \"\r"]
["P02787","Serotransferrin OS=Homo sapiens OX=9606 GN=TF","TF",77.063,323.31,76.1,73,294,73,1.091,1.071,1.07,0.919,0.932,0.928,0.86,3.87e-05,"extracellular\r","GO:0060627 regulation of vesicle-mediated transport; GO:0065008 regulation of biological quality; GO:0044699 single-organism process; GO:0048871 multicellular organismal homeostasis; GO:0015031 protein transport; GO:0097459 iron ion import into cell; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0000041 transition metal ion transport; GO:0032879 regulation of localization; GO:0055065 metal ion homeostasis; GO:0010035 response to inorganic substance; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0070887 cellular response to chemical stimulus; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0051716 cellular response to stimulus; GO:0015684 ferrous iron transport; GO:0048259 regulation of receptor-mediated endocytosis; GO:0050801 ion homeostasis; GO:0015682 ferric iron transport; GO:0044763 single-organism cellular process; GO:0098771 inorganic ion homeostasis; GO:0048522 positive regulation of cellular process; GO:0019725 cellular homeostasis; GO:0033572 transferrin transport; GO:0032501 multicellular organismal process; GO:0098657 import into cell; GO:0097286 iron ion import; GO:0010038 response to metal ion; GO:0051050 positive regulation of transport; GO:0046916 cellular transition metal ion homeostasis; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0001895 retina homeostasis; GO:0032940 secretion by cell; GO:0071281 cellular response to iron ion; GO:0001894 tissue homeostasis; GO:0071241 cellular response to inorganic substance; GO:0048260 positive regulation of receptor-mediated endocytosis; GO:0050794 regulation of cellular process; GO:0006879 cellular iron ion homeostasis; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0055076 transition metal ion homeostasis; GO:0072511 divalent inorganic cation transport; GO:0097460 ferrous iron import into cell; GO:0045807 positive regulation of endocytosis; GO:0030001 metal ion transport; GO:0030003 cellular cation homeostasis; GO:0055072 iron ion homeostasis; GO:0002576 platelet degranulation; GO:0006826 iron ion transport; GO:0050896 response to stimulus; GO:0055082 cellular chemical homeostasis; GO:0060249 anatomical structure homeostasis; GO:0042592 homeostatic process; GO:1902578 single-organism localization; GO:0055080 cation homeostasis; GO:0006812 cation transport; GO:0010039 response to iron ion; GO:0098659 inorganic cation import into cell; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0099587 inorganic ion import into cell; GO:0030100 regulation of endocytosis; GO:0051049 regulation of transport; GO:0016192 vesicle-mediated transport; GO:0071702 organic substance transport; GO:0048518 positive regulation of biological process; GO:0072512 trivalent inorganic cation transport; GO:0045184 establishment of protein localization; GO:0070627 ferrous iron import; GO:0045055 regulated exocytosis; GO:0006873 cellular ion homeostasis; GO:0006811 ion transport; GO:0061024 membrane organization; GO:0006875 cellular metal ion homeostasis; GO:0051128 regulation of cellular component organization; GO:0031647 regulation of protein stability; GO:0071248 cellular response to metal ion; GO:0051179 localization; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:0070838 divalent metal ion transport; GO:0006887 exocytosis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0009897 external side of plasma membrane; GO:0019898 extrinsic component of membrane; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0070062 extracellular exosome; GO:0098590 plasma membrane region; GO:0030136 clathrin-coated vesicle; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0098589 membrane region; GO:0043227 membrane-bounded organelle; GO:0045177 apical part of cell; GO:0043233 organelle lumen; GO:0098552 side of membrane; GO:0010008 endosome membrane; GO:1990712 HFE-transferrin receptor complex; GO:0005770 late endosome; GO:0031232 extrinsic component of external side of plasma membrane; GO:0098802 plasma membrane receptor complex; GO:0019897 extrinsic component of plasma membrane; GO:0043235 receptor complex; GO:0012506 vesicle membrane; GO:0044440 endosomal part; GO:0030135 coated vesicle; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0005905 clathrin-coated pit; GO:0043230 extracellular organelle; GO:0016323 basolateral plasma membrane; GO:0034774 secretory granule lumen; GO:0005615 extracellular space; GO:0016324 apical plasma membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0030662 coated vesicle membrane; GO:0055037 recycling endosome; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0005768 endosome; GO:0030141 secretory granule; GO:0030139 endocytic vesicle; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0030665 clathrin-coated vesicle membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0072562 blood microparticle; GO:0044459 plasma membrane part; GO:0060205 cytoplasmic vesicle lumen; GO:0009925 basal plasma membrane; GO:0009986 cell surface; GO:0044444 cytoplasmic part; GO:0045178 basal part of cell; ","GO:0005506 iron ion binding; GO:0015075 ion transmembrane transporter activity; GO:0005102 receptor binding; GO:0043167 ion binding; GO:0046915 transition metal ion transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0022891 substrate-specific transmembrane transporter activity; GO:0072510 trivalent inorganic cation transmembrane transporter activity; GO:0046873 metal ion transmembrane transporter activity; GO:0015091 ferric iron transmembrane transporter activity; GO:0046914 transition metal ion binding; GO:0008199 ferric iron binding; GO:0005381 iron ion transmembrane transporter activity; GO:0005488 binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0022890 inorganic cation transmembrane transporter activity; GO:1990459 transferrin receptor binding; GO:0008324 cation transmembrane transporter activity; GO:0022857 transmembrane transporter activity; GO:0005215 transporter activity; GO:0008198 ferrous iron binding; ","K14736","TF; transferrin","hsa04978 Mineral absorption - Homo sapiens (human); hsa04066 HIF-1 signaling pathway - Homo sapiens (human); hsa04216 Ferroptosis - Homo sapiens (human); ","IPR001156; ","Transferrin-like domain; \r"]
["P02788","Lactotransferrin OS=Homo sapiens OX=9606 GN=LTF","LTF",78.181,142.03,37.2,25,43,25,0.591,0.594,0.576,1.397,1.401,1.382,2.374,6.26e-08,"extracellular\r","GO:0010941 regulation of cell death; GO:0032680 regulation of tumor necrosis factor production; GO:0098542 defense response to other organism; GO:0070169 positive regulation of biomineral tissue development; GO:0031347 regulation of defense response; GO:0044237 cellular metabolic process; GO:0009607 response to biotic stimulus; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0008152 metabolic process; GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling; GO:0044093 positive regulation of molecular function; GO:0055065 metal ion homeostasis; GO:0019732 antifungal humoral response; GO:0045667 regulation of osteoblast differentiation; GO:0033690 positive regulation of osteoblast proliferation; GO:1900190 regulation of single-species biofilm formation; GO:0042325 regulation of phosphorylation; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0043086 negative regulation of catalytic activity; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0002385 mucosal immune response; GO:0006810 transport; GO:0051092 positive regulation of NF-kappaB transcription factor activity; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0045670 regulation of osteoclast differentiation; GO:0010721 negative regulation of cell development; GO:0060548 negative regulation of cell death; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0044707 single-multicellular organism process; GO:0048519 negative regulation of biological process; GO:1903706 regulation of hemopoiesis; GO:0051817 modification of morphology or physiology of other organism involved in symbiotic interaction; GO:0009653 anatomical structure morphogenesis; GO:0023057 negative regulation of signaling; GO:0046483 heterocycle metabolic process; GO:0010648 negative regulation of cell communication; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:1900191 negative regulation of single-species biofilm formation; GO:0051702 interaction with symbiont; GO:0048878 chemical homeostasis; GO:1902732 positive regulation of chondrocyte proliferation; GO:0006950 response to stress; GO:0060284 regulation of cell development; GO:0032101 regulation of response to external stimulus; GO:0002376 immune system process; GO:1901576 organic substance biosynthetic process; GO:0002263 cell activation involved in immune response; GO:0060348 bone development; GO:1902106 negative regulation of leukocyte differentiation; GO:0045055 regulated exocytosis; GO:1903011 negative regulation of bone development; GO:0030278 regulation of ossification; GO:0031325 positive regulation of cellular metabolic process; GO:0002251 organ or tissue specific immune response; GO:0006955 immune response; GO:0033214 iron assimilation by chelation and transport; GO:0008284 positive regulation of cell proliferation; GO:0051093 negative regulation of developmental process; GO:0009968 negative regulation of signal transduction; GO:0045637 regulation of myeloid cell differentiation; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:2001141 regulation of RNA biosynthetic process; GO:0032780 negative regulation of ATPase activity; GO:0009893 positive regulation of metabolic process; GO:0033674 positive regulation of kinase activity; GO:0019731 antibacterial humoral response; GO:0034121 regulation of toll-like receptor signaling pathway; GO:0048525 negative regulation of viral process; GO:0002832 negative regulation of response to biotic stimulus; GO:0045937 positive regulation of phosphate metabolic process; GO:0031326 regulation of cellular biosynthetic process; GO:1903012 positive regulation of bone development; GO:0098771 inorganic ion homeostasis; GO:0044788 modulation by host of viral process; GO:0002444 myeloid leukocyte mediated immunity; GO:0006351 transcription, DNA-templated; GO:0032940 secretion by cell; GO:1902105 regulation of leukocyte differentiation; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0006952 defense response; GO:2001204 regulation of osteoclast development; GO:0051851 modification by host of symbiont morphology or physiology; GO:0043549 regulation of kinase activity; GO:0043069 negative regulation of programmed cell death; GO:0002831 regulation of response to biotic stimulus; GO:0060255 regulation of macromolecule metabolic process; GO:0051707 response to other organism; GO:0045087 innate immune response; GO:0051346 negative regulation of hydrolase activity; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0060349 bone morphogenesis; GO:0055080 cation homeostasis; GO:0043066 negative regulation of apoptotic process; GO:0023056 positive regulation of signaling; GO:0034641 cellular nitrogen compound metabolic process; GO:1903707 negative regulation of hemopoiesis; GO:0010647 positive regulation of cell communication; GO:0009059 macromolecule biosynthetic process; GO:0002227 innate immune response in mucosa; GO:0045595 regulation of cell differentiation; GO:0045671 negative regulation of osteoclast differentiation; GO:0006355 regulation of transcription, DNA-templated; GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway; GO:0042742 defense response to bacterium; GO:0001932 regulation of protein phosphorylation; GO:0001934 positive regulation of protein phosphorylation; GO:0044249 cellular biosynthetic process; GO:0043901 negative regulation of multi-organism process; GO:0043085 positive regulation of catalytic activity; GO:0002366 leukocyte activation involved in immune response; GO:0050832 defense response to fungus; GO:0042119 neutrophil activation; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0002684 positive regulation of immune system process; GO:0001817 regulation of cytokine production; GO:0010467 gene expression; GO:1900157 regulation of bone mineralization involved in bone maturation; GO:0042981 regulation of apoptotic process; GO:1900229 negative regulation of single-species biofilm formation in or on host organism; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0045321 leukocyte activation; GO:0002762 negative regulation of myeloid leukocyte differentiation; GO:0097659 nucleic acid-templated transcription; GO:0030500 regulation of bone mineralization; GO:0070167 regulation of biomineral tissue development; GO:0009605 response to external stimulus; GO:1903010 regulation of bone development; GO:0051240 positive regulation of multicellular organismal process; GO:0032102 negative regulation of response to external stimulus; GO:0010562 positive regulation of phosphorus metabolic process; GO:0042327 positive regulation of phosphorylation; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0051347 positive regulation of transferase activity; GO:0044419 interspecies interaction between organisms; GO:2000307 regulation of tumor necrosis factor (ligand) superfamily member 11 production; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0051174 regulation of phosphorus metabolic process; GO:0009620 response to fungus; GO:0002443 leukocyte mediated immunity; GO:0018130 heterocycle biosynthetic process; GO:0019730 antimicrobial humoral response; GO:0001503 ossification; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0046916 cellular transition metal ion homeostasis; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0051336 regulation of hydrolase activity; GO:0001895 retina homeostasis; GO:0045669 positive regulation of osteoblast differentiation; GO:0050790 regulation of catalytic activity; GO:0051090 regulation of sequence-specific DNA binding transcription factor activity; GO:0010604 positive regulation of macromolecule metabolic process; GO:0009887 animal organ morphogenesis; GO:0002682 regulation of immune system process; GO:0051094 positive regulation of developmental process; GO:1901362 organic cyclic compound biosynthetic process; GO:0050794 regulation of cellular process; GO:0055076 transition metal ion homeostasis; GO:0002283 neutrophil activation involved in immune response; GO:0044793 negative regulation by host of viral process; GO:0042127 regulation of cell proliferation; GO:0031399 regulation of protein modification process; GO:0045778 positive regulation of ossification; GO:0044267 cellular protein metabolic process; GO:0043067 regulation of programmed cell death; GO:0055072 iron ion homeostasis; GO:0071902 positive regulation of protein serine/threonine kinase activity; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:0045597 positive regulation of cell differentiation; GO:0051239 regulation of multicellular organismal process; GO:0060249 anatomical structure homeostasis; GO:1903901 negative regulation of viral life cycle; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0019438 aromatic compound biosynthetic process; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:0009617 response to bacterium; GO:1902531 regulation of intracellular signal transduction; GO:0048731 system development; GO:0043900 regulation of multi-organism process; GO:0016192 vesicle-mediated transport; GO:0034143 regulation of toll-like receptor 4 signaling pathway; GO:0034654 nucleobase-containing compound biosynthetic process; GO:2001205 negative regulation of osteoclast development; GO:0045071 negative regulation of viral genome replication; GO:0044238 primary metabolic process; GO:0048705 skeletal system morphogenesis; GO:0051247 positive regulation of protein metabolic process; GO:0006873 cellular ion homeostasis; GO:0006811 ion transport; GO:0002761 regulation of myeloid leukocyte differentiation; GO:0001775 cell activation; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0006887 exocytosis; GO:1903555 regulation of tumor necrosis factor superfamily cytokine production; GO:0033212 iron assimilation; GO:1902533 positive regulation of intracellular signal transduction; GO:0051241 negative regulation of multicellular organismal process; GO:0001818 negative regulation of cytokine production; GO:0035821 modification of morphology or physiology of other organism; GO:0048871 multicellular organismal homeostasis; GO:0033688 regulation of osteoblast proliferation; GO:0051234 establishment of localization; GO:2000308 negative regulation of tumor necrosis factor (ligand) superfamily member 11 production; GO:0010646 regulation of cell communication; GO:0045088 regulation of innate immune response; GO:0045596 negative regulation of cell differentiation; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0050801 ion homeostasis; GO:0045638 negative regulation of myeloid cell differentiation; GO:0002446 neutrophil mediated immunity; GO:0019725 cellular homeostasis; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity; GO:0045069 regulation of viral genome replication; GO:0016070 RNA metabolic process; GO:0002683 negative regulation of immune system process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0043462 regulation of ATPase activity; GO:1900159 positive regulation of bone mineralization involved in bone maturation; GO:0001894 tissue homeostasis; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0043299 leukocyte degranulation; GO:0048856 anatomical structure development; GO:0001501 skeletal system development; GO:2000026 regulation of multicellular organismal development; GO:0006879 cellular iron ion homeostasis; GO:0045859 regulation of protein kinase activity; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0006725 cellular aromatic compound metabolic process; GO:0034123 positive regulation of toll-like receptor signaling pathway; GO:0002252 immune effector process; GO:0030003 cellular cation homeostasis; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0006959 humoral immune response; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0055082 cellular chemical homeostasis; GO:1900228 regulation of single-species biofilm formation in or on host organism; GO:1903556 negative regulation of tumor necrosis factor superfamily cytokine production; GO:0006508 proteolysis; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0034145 positive regulation of toll-like receptor 4 signaling pathway; GO:0050792 regulation of viral process; GO:0006807 nitrogen compound metabolic process; GO:0031401 positive regulation of protein modification process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0045860 positive regulation of protein kinase activity; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling; GO:0030501 positive regulation of bone mineralization; GO:0006875 cellular metal ion homeostasis; GO:0009967 positive regulation of signal transduction; GO:1903900 regulation of viral life cycle; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:1904724 tertiary granule lumen; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0030139 endocytic vesicle; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0070820 tertiary granule; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0045335 phagocytic vesicle; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0097013 phagocytic vesicle lumen; GO:0035580 specific granule lumen; GO:0042581 specific granule; GO:0009986 cell surface; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0071682 endocytic vesicle lumen; ","GO:0008233 peptidase activity; GO:0008236 serine-type peptidase activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0019207 kinase regulator activity; GO:0098772 molecular function regulator; GO:0008201 heparin binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0019209 kinase activator activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0005539 glycosaminoglycan binding; GO:0008047 enzyme activator activity; GO:0003677 DNA binding; GO:0005506 iron ion binding; GO:0030295 protein kinase activator activity; GO:0043539 protein serine/threonine kinase activator activity; GO:0043167 ion binding; GO:0019887 protein kinase regulator activity; GO:1901681 sulfur compound binding; GO:0004252 serine-type endopeptidase activity; GO:0004175 endopeptidase activity; GO:0097367 carbohydrate derivative binding; GO:0046914 transition metal ion binding; GO:0030234 enzyme regulator activity; GO:0017171 serine hydrolase activity; GO:0003676 nucleic acid binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0046872 metal ion binding; ","K17283",null,null,"IPR001156; ","Transferrin-like domain; \r"]
["P02790","Hemopexin OS=Homo sapiens OX=9606 GN=HPX","HPX",51.676,232.75,47,19,71,19,1.041,1.045,1.029,0.958,0.973,0.943,0.923,0.00136,"extracellular\r","GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0060330 regulation of response to interferon-gamma; GO:0031347 regulation of defense response; GO:0060332 positive regulation of response to interferon-gamma; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0055065 metal ion homeostasis; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0044765 single-organism transport; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:0002639 positive regulation of immunoglobulin production; GO:0060760 positive regulation of response to cytokine stimulus; GO:0046427 positive regulation of JAK-STAT cascade; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0031323 regulation of cellular metabolic process; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0046916 cellular transition metal ion homeostasis; GO:0006810 transport; GO:0042510 regulation of tyrosine phosphorylation of Stat1 protein; GO:0002889 regulation of immunoglobulin mediated immune response; GO:0002923 regulation of humoral immune response mediated by circulating immunoglobulin; GO:0044710 single-organism metabolic process; GO:0060759 regulation of response to cytokine stimulus; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0002682 regulation of immune system process; GO:0002821 positive regulation of adaptive immune response; GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation; GO:0050794 regulation of cellular process; GO:0055076 transition metal ion homeostasis; GO:0042509 regulation of tyrosine phosphorylation of STAT protein; GO:0031399 regulation of protein modification process; GO:0002920 regulation of humoral immune response; GO:0055072 iron ion homeostasis; GO:0060334 regulation of interferon-gamma-mediated signaling pathway; GO:0080134 regulation of response to stress; GO:0042511 positive regulation of tyrosine phosphorylation of Stat1 protein; GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0031349 positive regulation of defense response; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0006898 receptor-mediated endocytosis; GO:0050778 positive regulation of immune response; GO:0009966 regulation of signal transduction; GO:0048878 chemical homeostasis; GO:1904892 regulation of STAT cascade; GO:1902531 regulation of intracellular signal transduction; GO:0016192 vesicle-mediated transport; GO:0001961 positive regulation of cytokine-mediated signaling pathway; GO:0071702 organic substance transport; GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein; GO:0044238 primary metabolic process; GO:0051247 positive regulation of protein metabolic process; GO:0006873 cellular ion homeostasis; GO:0031325 positive regulation of cellular metabolic process; GO:1901678 iron coordination entity transport; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:1901564 organonitrogen compound metabolic process; GO:0002702 positive regulation of production of molecular mediator of immune response; GO:0002922 positive regulation of humoral immune response; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:1904894 positive regulation of STAT cascade; GO:0051234 establishment of localization; GO:0010646 regulation of cell communication; GO:0045088 regulation of innate immune response; GO:0009893 positive regulation of metabolic process; GO:0015886 heme transport; GO:0002819 regulation of adaptive immune response; GO:0002697 regulation of immune effector process; GO:0002708 positive regulation of lymphocyte mediated immunity; GO:0045937 positive regulation of phosphate metabolic process; GO:0050801 ion homeostasis; GO:0051181 cofactor transport; GO:0098771 inorganic ion homeostasis; GO:0019725 cellular homeostasis; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0002700 regulation of production of molecular mediator of immune response; GO:0051186 cofactor metabolic process; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0002705 positive regulation of leukocyte mediated immunity; GO:0033013 tetrapyrrole metabolic process; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin; GO:0002891 positive regulation of immunoglobulin mediated immune response; GO:0006879 cellular iron ion homeostasis; GO:0020027 hemoglobin metabolic process; GO:0046425 regulation of JAK-STAT cascade; GO:0006725 cellular aromatic compound metabolic process; GO:0060335 positive regulation of interferon-gamma-mediated signaling pathway; GO:0050730 regulation of peptidyl-tyrosine phosphorylation; GO:0060255 regulation of macromolecule metabolic process; GO:0030003 cellular cation homeostasis; GO:0001959 regulation of cytokine-mediated signaling pathway; GO:0042168 heme metabolic process; GO:0002706 regulation of lymphocyte mediated immunity; GO:0055082 cellular chemical homeostasis; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0006778 porphyrin-containing compound metabolic process; GO:0055080 cation homeostasis; GO:0023056 positive regulation of signaling; GO:0016032 viral process; GO:0010647 positive regulation of cell communication; GO:0002714 positive regulation of B cell mediated immunity; GO:0009987 cellular process; GO:0045089 positive regulation of innate immune response; GO:0042440 pigment metabolic process; GO:0002699 positive regulation of immune effector process; GO:0002712 regulation of B cell mediated immunity; GO:0001932 regulation of protein phosphorylation; GO:0006807 nitrogen compound metabolic process; GO:0031401 positive regulation of protein modification process; GO:0001934 positive regulation of protein phosphorylation; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0002703 regulation of leukocyte mediated immunity; GO:0051246 regulation of protein metabolic process; GO:0002637 regulation of immunoglobulin production; GO:0002684 positive regulation of immune system process; GO:0006875 cellular metal ion homeostasis; GO:0009967 positive regulation of signal transduction; GO:0071705 nitrogen compound transport; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0031983 vesicle lumen; GO:0072562 blood microparticle; GO:0060205 cytoplasmic vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0030139 endocytic vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0071682 endocytic vesicle lumen; ","GO:0015232 heme transporter activity; GO:0005488 binding; GO:0043167 ion binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0051184 cofactor transporter activity; GO:0005215 transporter activity; ","K18977",null,null,"IPR000585; ","Hemopexin-like domain; \r"]
["P02792","Ferritin light chain OS=Homo sapiens OX=9606 GN=FTL","FTL",20.019,58.163,44.6,7,12,7,0.986,1.101,1.007,1.039,1.009,0.925,0.961,0.457,"cytoplasm\r","GO:0006879 cellular iron ion homeostasis; GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0002283 neutrophil activation involved in immune response; GO:0055076 transition metal ion homeostasis; GO:0002252 immune effector process; GO:0030001 metal ion transport; GO:0030003 cellular cation homeostasis; GO:0055072 iron ion homeostasis; GO:0044699 single-organism process; GO:0006826 iron ion transport; GO:0050896 response to stimulus; GO:0055082 cellular chemical homeostasis; GO:0051234 establishment of localization; GO:0000041 transition metal ion transport; GO:0042592 homeostatic process; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0006812 cation transport; GO:0055080 cation homeostasis; GO:0055065 metal ion homeostasis; GO:0051235 maintenance of location; GO:0036230 granulocyte activation; GO:0051651 maintenance of location in cell; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0002443 leukocyte mediated immunity; GO:0097577 sequestering of iron ion; GO:0050801 ion homeostasis; GO:0002446 neutrophil mediated immunity; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0098771 inorganic ion homeostasis; GO:0019725 cellular homeostasis; GO:0002376 immune system process; GO:0043312 neutrophil degranulation; GO:0002263 cell activation involved in immune response; GO:0002444 myeloid leukocyte mediated immunity; GO:0006880 intracellular sequestering of iron ion; GO:0051641 cellular localization; GO:0046916 cellular transition metal ion homeostasis; GO:0002366 leukocyte activation involved in immune response; GO:0006810 transport; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:0006873 cellular ion homeostasis; GO:0032940 secretion by cell; GO:0006811 ion transport; GO:0001775 cell activation; GO:0006875 cellular metal ion homeostasis; GO:0043299 leukocyte degranulation; GO:0006955 immune response; GO:0051179 localization; GO:0051238 sequestering of metal ion; GO:0006887 exocytosis; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044754 autolysosome; GO:0044424 intracellular part; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:0044422 organelle part; GO:0005776 autophagosome; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0005767 secondary lysosome; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0008043 intracellular ferritin complex; GO:0042582 azurophil granule; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0070288 ferritin complex; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0042802 identical protein binding; GO:0005506 iron ion binding; GO:0008199 ferric iron binding; GO:0046914 transition metal ion binding; GO:0005488 binding; GO:0043167 ion binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; ","K13625","FTL; ferritin light chain","hsa04978 Mineral absorption - Homo sapiens (human); hsa04216 Ferroptosis - Homo sapiens (human); hsa04217 Necroptosis - Homo sapiens (human); ","IPR012347; IPR009040; IPR009078; IPR008331; ","Ferritin-related; Ferritin-like diiron domain; Ferritin-like superfamily; Ferritin/DPS protein domain; \r"]
["P02794","Ferritin heavy chain OS=Homo sapiens OX=9606 GN=FTH1","FTH1",21.225,134.93,66.7,11,21,11,0.977,0.997,0.976,1.051,0.976,1.043,1.041,0.183,"cytoplasm\r","GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0044699 single-organism process; GO:0008285 negative regulation of cell proliferation; GO:0051234 establishment of localization; GO:0048145 regulation of fibroblast proliferation; GO:0000041 transition metal ion transport; GO:0008152 metabolic process; GO:0048147 negative regulation of fibroblast proliferation; GO:0055065 metal ion homeostasis; GO:0051651 maintenance of location in cell; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0002443 leukocyte mediated immunity; GO:0050801 ion homeostasis; GO:0055114 oxidation-reduction process; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0098771 inorganic ion homeostasis; GO:0019725 cellular homeostasis; GO:0097286 iron ion import; GO:0002444 myeloid leukocyte mediated immunity; GO:0006880 intracellular sequestering of iron ion; GO:0046916 cellular transition metal ion homeostasis; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0032940 secretion by cell; GO:0044710 single-organism metabolic process; GO:0043299 leukocyte degranulation; GO:0051238 sequestering of metal ion; GO:0006879 cellular iron ion homeostasis; GO:0050794 regulation of cellular process; GO:0055076 transition metal ion homeostasis; GO:0002283 neutrophil activation involved in immune response; GO:0042127 regulation of cell proliferation; GO:0002252 immune effector process; GO:0030001 metal ion transport; GO:0030003 cellular cation homeostasis; GO:0055072 iron ion homeostasis; GO:0006826 iron ion transport; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:0055082 cellular chemical homeostasis; GO:0042592 homeostatic process; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0055080 cation homeostasis; GO:0006812 cation transport; GO:0051235 maintenance of location; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0097577 sequestering of iron ion; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0043312 neutrophil degranulation; GO:0002263 cell activation involved in immune response; GO:0051641 cellular localization; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0006873 cellular ion homeostasis; GO:0006811 ion transport; GO:0001775 cell activation; GO:0006875 cellular metal ion homeostasis; GO:0051179 localization; GO:0006955 immune response; GO:0065007 biological regulation; GO:0006887 exocytosis; ","GO:1904724 tertiary granule lumen; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044754 autolysosome; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0005776 autophagosome; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0005767 secondary lysosome; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0070820 tertiary granule; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0008043 intracellular ferritin complex; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0070288 ferritin complex; GO:0005773 vacuole; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016722 oxidoreductase activity, oxidizing metal ions; GO:0005506 iron ion binding; GO:0016724 oxidoreductase activity, oxidizing metal ions, oxygen as acceptor; GO:0008199 ferric iron binding; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0004322 ferroxidase activity; GO:0016491 oxidoreductase activity; ","K00522","FTH1; ferritin heavy chain [EC:1.16.3.2]","hsa04978 Mineral absorption - Homo sapiens (human); hsa04216 Ferroptosis - Homo sapiens (human); hsa04217 Necroptosis - Homo sapiens (human); ","IPR012347; IPR009040; IPR009078; IPR008331; ","Ferritin-related; Ferritin-like diiron domain; Ferritin-like superfamily; Ferritin/DPS protein domain; \r"]
["P03923","NADH-ubiquinone oxidoreductase chain 6 OS=Homo sapiens OX=9606 GN=MT-ND6","MT-ND6",18.622,3.434,8,1,1,1,1.045,1.018,1.09,0.934,0.91,1.014,0.906,0.0608,"plasma membrane\r","GO:0044085 cellular component biogenesis; GO:0035094 response to nicotine; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0022607 cellular component assembly; GO:0006753 nucleoside phosphate metabolic process; GO:0065003 macromolecular complex assembly; GO:0007005 mitochondrion organization; GO:0006979 response to oxidative stress; GO:0019693 ribose phosphate metabolic process; GO:0009719 response to endogenous stimulus; GO:0010035 response to inorganic substance; GO:0014070 response to organic cyclic compound; GO:0071822 protein complex subunit organization; GO:0060359 response to ammonium ion; GO:0010257 NADH dehydrogenase complex assembly; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0000302 response to reactive oxygen species; GO:0006119 oxidative phosphorylation; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0006120 mitochondrial electron transport, NADH to ubiquinone; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0010243 response to organonitrogen compound; GO:0097031 mitochondrial respiratory chain complex I biogenesis; GO:0042221 response to chemical; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:1901698 response to nitrogen compound; GO:0022900 electron transport chain; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0070271 protein complex biogenesis; GO:0042220 response to cocaine; GO:0033108 mitochondrial respiratory chain complex assembly; GO:0016043 cellular component organization; GO:0016310 phosphorylation; GO:0006725 cellular aromatic compound metabolic process; GO:0042773 ATP synthesis coupled electron transport; GO:0009259 ribonucleotide metabolic process; GO:1901700 response to oxygen-containing compound; GO:0043279 response to alkaloid; GO:0022904 respiratory electron transport chain; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0032981 mitochondrial respiratory chain complex I assembly; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0009119 ribonucleoside metabolic process; GO:0006461 protein complex assembly; GO:0043623 cellular protein complex assembly; GO:0046034 ATP metabolic process; GO:0034622 cellular macromolecular complex assembly; GO:0006950 response to stress; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0045333 cellular respiration; GO:0006163 purine nucleotide metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0046128 purine ribonucleoside metabolic process; GO:0006793 phosphorus metabolic process; GO:0042542 response to hydrogen peroxide; GO:0006996 organelle organization; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:1901564 organonitrogen compound metabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044429 mitochondrial part; GO:0031090 organelle membrane; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0005740 mitochondrial envelope; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0031975 envelope; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0070469 respiratory chain; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0050136 NADH dehydrogenase (quinone) activity; GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:0003954 NADH dehydrogenase activity; GO:0003824 catalytic activity; GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; GO:0008137 NADH dehydrogenase (ubiquinone) activity; GO:0016491 oxidoreductase activity; ","K03884","ND6; NADH-ubiquinone oxidoreductase chain 6 [EC:1.6.5.3]","hsa04714 Thermogenesis - Homo sapiens (human); hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); "]
["P03928","ATP synthase protein 8 OS=Homo sapiens OX=9606 GN=MT-ATP8","MT-ATP8",7.9916,4.1462,29.4,2,2,2,0.921,0.945,0.82,1.1,1.046,1.165,1.233,0.0173,"extracellular\r","GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0006839 mitochondrial transport; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0046129 purine ribonucleoside biosynthetic process; GO:0009163 nucleoside biosynthetic process; GO:0009156 ribonucleoside monophosphate biosynthetic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0046390 ribose phosphate biosynthetic process; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:1901137 carbohydrate derivative biosynthetic process; GO:0006753 nucleoside phosphate metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0009145 purine nucleoside triphosphate biosynthetic process; GO:0044765 single-organism transport; GO:0018130 heterocycle biosynthetic process; GO:0098655 cation transmembrane transport; GO:0009206 purine ribonucleoside triphosphate biosynthetic process; GO:0044281 small molecule metabolic process; GO:0006754 ATP biosynthetic process; GO:0044763 single-organism cellular process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0015985 energy coupled proton transport, down electrochemical gradient; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0009168 purine ribonucleoside monophosphate biosynthetic process; GO:1902582 single-organism intracellular transport; GO:0042451 purine nucleoside biosynthetic process; GO:0036296 response to increased oxygen levels; GO:0090407 organophosphate biosynthetic process; GO:0006810 transport; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0072522 purine-containing compound biosynthetic process; GO:0015986 ATP synthesis coupled proton transport; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0006164 purine nucleotide biosynthetic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0098662 inorganic cation transmembrane transport; GO:0009201 ribonucleoside triphosphate biosynthetic process; GO:0046907 intracellular transport; GO:0034220 ion transmembrane transport; GO:0009165 nucleotide biosynthetic process; GO:0042776 mitochondrial ATP synthesis coupled proton transport; GO:0006725 cellular aromatic compound metabolic process; GO:0009628 response to abiotic stimulus; GO:0009259 ribonucleotide metabolic process; GO:0009142 nucleoside triphosphate biosynthetic process; GO:0050896 response to stimulus; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0006812 cation transport; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:1990542 mitochondrial transmembrane transport; GO:0070482 response to oxygen levels; GO:1901135 carbohydrate derivative metabolic process; GO:1902600 hydrogen ion transmembrane transport; GO:0034641 cellular nitrogen compound metabolic process; GO:1902580 single-organism cellular localization; GO:0055093 response to hyperoxia; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0009119 ribonucleoside metabolic process; GO:0046034 ATP metabolic process; GO:0009124 nucleoside monophosphate biosynthetic process; GO:0006950 response to stress; GO:0044711 single-organism biosynthetic process; GO:0098660 inorganic ion transmembrane transport; GO:0009127 purine nucleoside monophosphate biosynthetic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0042455 ribonucleoside biosynthetic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0006163 purine nucleotide metabolic process; GO:0006818 hydrogen transport; GO:0015992 proton transport; GO:0051641 cellular localization; GO:0046128 purine ribonucleoside metabolic process; GO:0055085 transmembrane transport; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0009152 purine ribonucleotide biosynthetic process; GO:0006793 phosphorus metabolic process; GO:1901659 glycosyl compound biosynthetic process; GO:0006811 ion transport; GO:0009260 ribonucleotide biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0051179 localization; GO:0015672 monovalent inorganic cation transport; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0032991 macromolecular complex; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044455 mitochondrial membrane part; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain; GO:0005743 mitochondrial inner membrane; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o); GO:0016021 integral component of membrane; GO:0045259 proton-transporting ATP synthase complex; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005753 mitochondrial proton-transporting ATP synthase complex; GO:0016469 proton-transporting two-sector ATPase complex; GO:0031975 envelope; GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o); GO:0043234 protein complex; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0015075 ion transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0015077 monovalent inorganic cation transmembrane transporter activity; GO:0022890 inorganic cation transmembrane transporter activity; GO:0015078 hydrogen ion transmembrane transporter activity; GO:0008324 cation transmembrane transporter activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; ","K02125","ATPeF08; F-type H+-transporting ATPase subunit 8","hsa05010 Alzheimer's disease - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); "]
["P03950","Angiogenin OS=Homo sapiens OX=9606 GN=ANG","ANG",16.55,34.781,51,7,11,7,0.952,1.055,1.199,1.005,0.91,0.919,0.884,0.18,"extracellular\r","GO:0044085 cellular component biogenesis; GO:0021700 developmental maturation; GO:0022414 reproductive process; GO:0010608 posttranscriptional regulation of gene expression; GO:0098542 defense response to other organism; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0001878 response to yeast; GO:0008610 lipid biosynthetic process; GO:0009607 response to biotic stimulus; GO:0008152 metabolic process; GO:0001525 angiogenesis; GO:0065003 macromolecular complex assembly; GO:0006639 acylglycerol metabolic process; GO:0044093 positive regulation of molecular function; GO:0034332 adherens junction organization; GO:0019732 antifungal humoral response; GO:1900274 regulation of phospholipase C activity; GO:0042325 regulation of phosphorylation; GO:0080090 regulation of primary metabolic process; GO:0060191 regulation of lipase activity; GO:0044763 single-organism cellular process; GO:0034249 negative regulation of cellular amide metabolic process; GO:0048870 cell motility; GO:0051704 multi-organism process; GO:0032430 positive regulation of phospholipase A2 activity; GO:0044260 cellular macromolecule metabolic process; GO:0051223 regulation of protein transport; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0090305 nucleic acid phosphodiester bond hydrolysis; GO:0048609 multicellular organismal reproductive process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0048599 oocyte development; GO:0072359 circulatory system development; GO:0000003 reproduction; GO:0044707 single-multicellular organism process; GO:0010517 regulation of phospholipase activity; GO:0048519 negative regulation of biological process; GO:0046545 development of primary female sexual characteristics; GO:0009653 anatomical structure morphogenesis; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0051345 positive regulation of hydrolase activity; GO:0009889 regulation of biosynthetic process; GO:0070482 response to oxygen levels; GO:0010518 positive regulation of phospholipase activity; GO:0001936 regulation of endothelial cell proliferation; GO:0061458 reproductive system development; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0006638 neutral lipid metabolic process; GO:0009994 oocyte differentiation; GO:0044711 single-organism biosynthetic process; GO:0006950 response to stress; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:1901576 organic substance biosynthetic process; GO:0034248 regulation of cellular amide metabolic process; GO:0009890 negative regulation of biosynthetic process; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0006955 immune response; GO:0008284 positive regulation of cell proliferation; GO:0046486 glycerolipid metabolic process; GO:0051674 localization of cell; GO:0001568 blood vessel development; GO:0048869 cellular developmental process; GO:0045216 cell-cell junction organization; GO:0051046 regulation of secretion; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0046460 neutral lipid biosynthetic process; GO:0009893 positive regulation of metabolic process; GO:0048469 cell maturation; GO:0033674 positive regulation of kinase activity; GO:0019731 antibacterial humoral response; GO:0006629 lipid metabolic process; GO:0016072 rRNA metabolic process; GO:0045937 positive regulation of phosphate metabolic process; GO:0048477 oogenesis; GO:0031326 regulation of cellular biosynthetic process; GO:0048608 reproductive structure development; GO:0001944 vasculature development; GO:1903530 regulation of secretion by cell; GO:0010605 negative regulation of macromolecule metabolic process; GO:0006351 transcription, DNA-templated; GO:0065009 regulation of molecular function; GO:0006952 defense response; GO:0070271 protein complex biogenesis; GO:0051222 positive regulation of protein transport; GO:0043549 regulation of kinase activity; GO:0016477 cell migration; GO:0016043 cellular component organization; GO:0060255 regulation of macromolecule metabolic process; GO:0007292 female gamete generation; GO:0032429 regulation of phospholipase A2 activity; GO:0051707 response to other organism; GO:0045087 innate immune response; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:0010863 positive regulation of phospholipase C activity; GO:0001666 response to hypoxia; GO:0034641 cellular nitrogen compound metabolic process; GO:0007202 activation of phospholipase C activity; GO:0009059 macromolecule biosynthetic process; GO:0045137 development of primary sexual characteristics; GO:0043623 cellular protein complex assembly; GO:0032148 activation of protein kinase B activity; GO:0034622 cellular macromolecular complex assembly; GO:0042742 defense response to bacterium; GO:0010629 negative regulation of gene expression; GO:0051049 regulation of transport; GO:0001932 regulation of protein phosphorylation; GO:0001934 positive regulation of protein phosphorylation; GO:0044249 cellular biosynthetic process; GO:0045017 glycerolipid biosynthetic process; GO:0043085 positive regulation of catalytic activity; GO:0043933 macromolecular complex subunit organization; GO:0048662 negative regulation of smooth muscle cell proliferation; GO:0050832 defense response to fungus; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044703 multi-organism reproductive process; GO:0051248 negative regulation of protein metabolic process; GO:0010467 gene expression; GO:0031327 negative regulation of cellular biosynthetic process; GO:0034660 ncRNA metabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0097659 nucleic acid-templated transcription; GO:0030041 actin filament polymerization; GO:0008285 negative regulation of cell proliferation; GO:0009605 response to external stimulus; GO:0030036 actin cytoskeleton organization; GO:0050678 regulation of epithelial cell proliferation; GO:0032879 regulation of localization; GO:0044702 single organism reproductive process; GO:0009719 response to endogenous stimulus; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0043170 macromolecule metabolic process; GO:0051347 positive regulation of transferase activity; GO:0003006 developmental process involved in reproduction; GO:0009620 response to fungus; GO:0051174 regulation of phosphorus metabolic process; GO:0018130 heterocycle biosynthetic process; GO:0019730 antimicrobial humoral response; GO:0019953 sexual reproduction; GO:0008154 actin polymerization or depolymerization; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0001938 positive regulation of endothelial cell proliferation; GO:0048513 animal organ development; GO:0051336 regulation of hydrolase activity; GO:0006651 diacylglycerol biosynthetic process; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0044710 single-organism metabolic process; GO:0008585 female gonad development; GO:0050714 positive regulation of protein secretion; GO:0010604 positive regulation of macromolecule metabolic process; GO:0097435 supramolecular fiber organization; GO:1901362 organic cyclic compound biosynthetic process; GO:0046339 diacylglycerol metabolic process; GO:0051047 positive regulation of secretion; GO:0050794 regulation of cellular process; GO:0042127 regulation of cell proliferation; GO:0001890 placenta development; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0008406 gonad development; GO:0017148 negative regulation of translation; GO:0048523 negative regulation of cellular process; GO:0042698 ovulation cycle; GO:0022602 ovulation cycle process; GO:0032147 activation of protein kinase activity; GO:0019438 aromatic compound biosynthetic process; GO:0001541 ovarian follicle development; GO:0098781 ncRNA transcription; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0007548 sex differentiation; GO:0007275 multicellular organism development; GO:0032880 regulation of protein localization; GO:0007010 cytoskeleton organization; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0006461 protein complex assembly; GO:0009617 response to bacterium; GO:0048731 system development; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0072358 cardiovascular system development; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0051247 positive regulation of protein metabolic process; GO:1904951 positive regulation of establishment of protein localization; GO:0030029 actin filament-based process; GO:0006928 movement of cell or subcellular component; GO:0036293 response to decreased oxygen levels; GO:0051179 localization; GO:0032431 activation of phospholipase A2 activity; GO:0046660 female sex differentiation; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0048514 blood vessel morphogenesis; GO:0009303 rRNA transcription; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0071822 protein complex subunit organization; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0050830 defense response to Gram-positive bacterium; GO:0051050 positive regulation of transport; GO:0060193 positive regulation of lipase activity; GO:0016070 RNA metabolic process; GO:1902589 single-organism organelle organization; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0090304 nucleic acid metabolic process; GO:1903532 positive regulation of secretion by cell; GO:0022412 cellular process involved in reproduction in multicellular organism; GO:0051258 protein polymerization; GO:0019222 regulation of metabolic process; GO:0040011 locomotion; GO:0019220 regulation of phosphate metabolic process; GO:0048856 anatomical structure development; GO:0045859 regulation of protein kinase activity; GO:0006725 cellular aromatic compound metabolic process; GO:0048660 regulation of smooth muscle cell proliferation; GO:0007015 actin filament organization; GO:0006959 humoral immune response; GO:0046463 acylglycerol biosynthetic process; GO:0043207 response to external biotic stimulus; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0070201 regulation of establishment of protein localization; GO:0001556 oocyte maturation; GO:0007281 germ cell development; GO:0050708 regulation of protein secretion; GO:0009987 cellular process; GO:0006807 nitrogen compound metabolic process; GO:0031401 positive regulation of protein modification process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045860 positive regulation of protein kinase activity; GO:0048518 positive regulation of biological process; GO:0007276 gamete generation; GO:0032504 multicellular organism reproduction; GO:0090501 RNA phosphodiester bond hydrolysis; GO:0034330 cell junction organization; GO:0006417 regulation of translation; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0048511 rhythmic process; GO:0009725 response to hormone; GO:0065007 biological regulation; GO:0050679 positive regulation of epithelial cell proliferation; ","GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0032311 angiogenin-PRI complex; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0043025 neuronal cell body; GO:0032991 macromolecular complex; GO:0030426 growth cone; GO:0044424 intracellular part; GO:0005623 cell; GO:0044420 extracellular matrix component; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005604 basement membrane; GO:0031974 membrane-enclosed lumen; GO:0005605 basal lamina; GO:0070062 extracellular exosome; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0030427 site of polarized growth; GO:0044463 cell projection part; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031012 extracellular matrix; GO:0005634 nucleus; GO:0036477 somatodendritic compartment; GO:0005578 proteinaceous extracellular matrix; GO:0044297 cell body; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005102 receptor binding; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0005507 copper ion binding; GO:0008201 heparin binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0008092 cytoskeletal protein binding; GO:0042802 identical protein binding; GO:0042277 peptide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0005539 glycosaminoglycan binding; GO:0004540 ribonuclease activity; GO:0004519 endonuclease activity; GO:0003677 DNA binding; GO:0003723 RNA binding; GO:0043167 ion binding; GO:0033218 amide binding; GO:1901681 sulfur compound binding; GO:0019843 rRNA binding; GO:0097367 carbohydrate derivative binding; GO:0046914 transition metal ion binding; GO:0042803 protein homodimerization activity; GO:0004518 nuclease activity; GO:0016788 hydrolase activity, acting on ester bonds; GO:0003676 nucleic acid binding; GO:0003779 actin binding; GO:0046872 metal ion binding; ","K16631",null,null,"IPR023412; ","Ribonuclease A-domain; \r"]
["P03951","Coagulation factor XI OS=Homo sapiens OX=9606 GN=F11","F11",70.108,5.5616,4.8,3,3,3,0.904,1.049,1.019,1.165,0.846,1.029,1.023,0.884,"extracellular\r","GO:0044707 single-multicellular organism process; GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0030193 regulation of blood coagulation; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0048519 negative regulation of biological process; GO:0016485 protein processing; GO:0080134 regulation of response to stress; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:0007599 hemostasis; GO:0071704 organic substance metabolic process; GO:1900047 negative regulation of hemostasis; GO:0009611 response to wounding; GO:0008152 metabolic process; GO:0032102 negative regulation of response to external stimulus; GO:0031639 plasminogen activation; GO:1900046 regulation of hemostasis; GO:0006508 proteolysis; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0051919 positive regulation of fibrinolysis; GO:0031638 zymogen activation; GO:0050878 regulation of body fluid levels; GO:0006950 response to stress; GO:0007597 blood coagulation, intrinsic pathway; GO:0051917 regulation of fibrinolysis; GO:0072376 protein activation cascade; GO:0032101 regulation of response to external stimulus; GO:0048585 negative regulation of response to stimulus; GO:0044238 primary metabolic process; GO:0061045 negative regulation of wound healing; GO:0048518 positive regulation of biological process; GO:0032501 multicellular organismal process; GO:0072378 blood coagulation, fibrin clot formation; GO:1903035 negative regulation of response to wounding; GO:0050818 regulation of coagulation; GO:0030195 negative regulation of blood coagulation; GO:0050789 regulation of biological process; GO:0042060 wound healing; GO:0061041 regulation of wound healing; GO:0048583 regulation of response to stimulus; GO:0010467 gene expression; GO:0050817 coagulation; GO:0051604 protein maturation; GO:1903034 regulation of response to wounding; GO:0050819 negative regulation of coagulation; GO:0065007 biological regulation; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0071944 cell periphery; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0005576 extracellular region; GO:0043230 extracellular organelle; GO:0005886 plasma membrane; ","GO:0008238 exopeptidase activity; GO:0008233 peptidase activity; GO:0043167 ion binding; GO:0008236 serine-type peptidase activity; GO:0004177 aminopeptidase activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0070008 serine-type exopeptidase activity; GO:0008201 heparin binding; GO:1901681 sulfur compound binding; GO:0070009 serine-type aminopeptidase activity; GO:0004252 serine-type endopeptidase activity; GO:0004175 endopeptidase activity; GO:0097367 carbohydrate derivative binding; GO:0003824 catalytic activity; GO:0017171 serine hydrolase activity; GO:0005488 binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0043168 anion binding; GO:0005539 glycosaminoglycan binding; ","K01323","F11; coagulation factor XI [EC:3.4.21.27]","hsa04610 Complement and coagulation cascades - Homo sapiens (human); ","IPR009003; IPR003609; IPR000177; IPR001254; ","\"Peptidase S1, PA clan; PAN/Apple domain; Apple domain; Serine proteases, trypsin domain; \"\r"]
["P03952","Plasma kallikrein OS=Homo sapiens OX=9606 GN=KLKB1","KLKB1",71.369,48.006,20.7,13,18,13,0.988,0.948,0.979,0.991,1,1.066,1.049,0.146,"extracellular\r","GO:0002675 positive regulation of acute inflammatory response; GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0016485 protein processing; GO:0031347 regulation of defense response; GO:0042730 fibrinolysis; GO:0009611 response to wounding; GO:0008152 metabolic process; GO:0009893 positive regulation of metabolic process; GO:0031639 plasminogen activation; GO:0032102 negative regulation of response to external stimulus; GO:0032103 positive regulation of response to external stimulus; GO:0022617 extracellular matrix disassembly; GO:1900046 regulation of hemostasis; GO:0030198 extracellular matrix organization; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0031638 zymogen activation; GO:0010468 regulation of gene expression; GO:0007597 blood coagulation, intrinsic pathway; GO:0050729 positive regulation of inflammatory response; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:1903035 negative regulation of response to wounding; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0002526 acute inflammatory response; GO:0048583 regulation of response to stimulus; GO:0006954 inflammatory response; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0050817 coagulation; GO:1903317 regulation of protein maturation; GO:0006952 defense response; GO:0002353 plasma kallikrein-kinin cascade; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0002254 kinin cascade; GO:1903319 positive regulation of protein maturation; GO:0060255 regulation of macromolecule metabolic process; GO:0030193 regulation of blood coagulation; GO:0002673 regulation of acute inflammatory response; GO:0048519 negative regulation of biological process; GO:0080134 regulation of response to stress; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:0007599 hemostasis; GO:0071704 organic substance metabolic process; GO:1900047 negative regulation of hemostasis; GO:0031349 positive regulation of defense response; GO:0045862 positive regulation of proteolysis; GO:0043062 extracellular structure organization; GO:0010628 positive regulation of gene expression; GO:0006508 proteolysis; GO:0051919 positive regulation of fibrinolysis; GO:0009987 cellular process; GO:0002542 Factor XII activation; GO:0050878 regulation of body fluid levels; GO:0006950 response to stress; GO:0051917 regulation of fibrinolysis; GO:0032101 regulation of response to external stimulus; GO:0072376 protein activation cascade; GO:0048585 negative regulation of response to stimulus; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0061045 negative regulation of wound healing; GO:0048518 positive regulation of biological process; GO:0072378 blood coagulation, fibrin clot formation; GO:0050818 regulation of coagulation; GO:0030195 negative regulation of blood coagulation; GO:0010954 positive regulation of protein processing; GO:0051247 positive regulation of protein metabolic process; GO:0061041 regulation of wound healing; GO:0042060 wound healing; GO:0051246 regulation of protein metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0070613 regulation of protein processing; GO:0050727 regulation of inflammatory response; GO:0022411 cellular component disassembly; GO:0010467 gene expression; GO:0051604 protein maturation; GO:0048584 positive regulation of response to stimulus; GO:1903034 regulation of response to wounding; GO:0050819 negative regulation of coagulation; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0071944 cell periphery; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0005576 extracellular region; GO:0043230 extracellular organelle; GO:0005886 plasma membrane; ","GO:0004252 serine-type endopeptidase activity; GO:0004175 endopeptidase activity; GO:0008233 peptidase activity; GO:0017171 serine hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0008236 serine-type peptidase activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0016787 hydrolase activity; GO:0005515 protein binding; ","K01324","KLKB1; plasma kallikrein [EC:3.4.21.34]","hsa04610 Complement and coagulation cascades - Homo sapiens (human); ","IPR009003; IPR000177; IPR003609; IPR001254; ","\"Peptidase S1, PA clan; Apple domain; PAN/Apple domain; Serine proteases, trypsin domain; \"\r"]
["P04003","C4b-binding protein alpha chain OS=Homo sapiens OX=9606 GN=C4BPA","C4BPA",67.033,75.916,30,17,28,17,0.872,0.882,0.913,1.071,1.067,1.102,1.215,0.000342,"plasma membrane\r","GO:0060627 regulation of vesicle-mediated transport; GO:0030450 regulation of complement activation, classical pathway; GO:0016064 immunoglobulin mediated immune response; GO:0002698 negative regulation of immune effector process; GO:1903318 negative regulation of protein maturation; GO:0045916 negative regulation of complement activation; GO:0031347 regulation of defense response; GO:0006956 complement activation; GO:0008152 metabolic process; GO:0002890 negative regulation of immunoglobulin mediated immune response; GO:0009893 positive regulation of metabolic process; GO:0032879 regulation of localization; GO:0002819 regulation of adaptive immune response; GO:0002250 adaptive immune response; GO:0006958 complement activation, classical pathway; GO:0050777 negative regulation of immune response; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0050764 regulation of phagocytosis; GO:0002697 regulation of immune effector process; GO:0010468 regulation of gene expression; GO:0002443 leukocyte mediated immunity; GO:0080090 regulation of primary metabolic process; GO:0009894 regulation of catabolic process; GO:0045959 negative regulation of complement activation, classical pathway; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0050776 regulation of immune response; GO:0002683 negative regulation of immune system process; GO:0002820 negative regulation of adaptive immune response; GO:0002889 regulation of immunoglobulin mediated immune response; GO:0002923 regulation of humoral immune response mediated by circulating immunoglobulin; GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0048583 regulation of response to stimulus; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0002682 regulation of immune system process; GO:0006952 defense response; GO:1903317 regulation of protein maturation; GO:0050794 regulation of cellular process; GO:0030449 regulation of complement activation; GO:2000257 regulation of protein activation cascade; GO:0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0002920 regulation of humoral immune response; GO:0010955 negative regulation of protein processing; GO:0002704 negative regulation of leukocyte mediated immunity; GO:0002673 regulation of acute inflammatory response; GO:0006959 humoral immune response; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0002921 negative regulation of humoral immune response; GO:0050896 response to stimulus; GO:0002706 regulation of lymphocyte mediated immunity; GO:0045087 innate immune response; GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0019724 B cell mediated immunity; GO:0071704 organic substance metabolic process; GO:2000258 negative regulation of protein activation cascade; GO:0009896 positive regulation of catabolic process; GO:0002707 negative regulation of lymphocyte mediated immunity; GO:0042176 regulation of protein catabolic process; GO:0002449 lymphocyte mediated immunity; GO:0050778 positive regulation of immune response; GO:0002253 activation of immune response; GO:0045861 negative regulation of proteolysis; GO:0030100 regulation of endocytosis; GO:0006950 response to stress; GO:0010629 negative regulation of gene expression; GO:0051049 regulation of transport; GO:0002712 regulation of B cell mediated immunity; GO:0032101 regulation of response to external stimulus; GO:0072376 protein activation cascade; GO:0002376 immune system process; GO:0048585 negative regulation of response to stimulus; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0048518 positive regulation of biological process; GO:0002703 regulation of leukocyte mediated immunity; GO:0051247 positive regulation of protein metabolic process; GO:1903027 regulation of opsonization; GO:0051246 regulation of protein metabolic process; GO:0002684 positive regulation of immune system process; GO:0050727 regulation of inflammatory response; GO:0070613 regulation of protein processing; GO:0051248 negative regulation of protein metabolic process; GO:0045732 positive regulation of protein catabolic process; GO:0051128 regulation of cellular component organization; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0048584 positive regulation of response to stimulus; GO:0006955 immune response; GO:0002713 negative regulation of B cell mediated immunity; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044217 other organism part; GO:0072562 blood microparticle; GO:0044421 extracellular region part; GO:0005615 extracellular space; GO:0044464 cell part; GO:0071944 cell periphery; GO:0044216 other organism cell; GO:0044215 other organism; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005515 protein binding; GO:0005488 binding; GO:0003676 nucleic acid binding; ","K04002","C4BPA; complement component 4 binding protein, alpha","hsa05133 Pertussis - Homo sapiens (human); hsa04610 Complement and coagulation cascades - Homo sapiens (human); ","IPR000436; ","Sushi/SCR/CCP domain; \r"]
["P04004","Vitronectin OS=Homo sapiens OX=9606 GN=VTN","VTN",54.305,42.291,18.4,7,19,7,0.997,1.011,0.957,0.995,0.952,1.032,1.005,0.884,"extracellular\r","GO:0060627 regulation of vesicle-mediated transport; GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0030335 positive regulation of cell migration; GO:0048732 gland development; GO:0032270 positive regulation of cellular protein metabolic process; GO:0031347 regulation of defense response; GO:0007492 endoderm development; GO:0022610 biological adhesion; GO:0010466 negative regulation of peptidase activity; GO:0048709 oligodendrocyte differentiation; GO:0065003 macromolecular complex assembly; GO:0032879 regulation of localization; GO:0032102 negative regulation of response to external stimulus; GO:0044093 positive regulation of molecular function; GO:0007160 cell-matrix adhesion; GO:0090303 positive regulation of wound healing; GO:0007155 cell adhesion; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0009790 embryo development; GO:0051099 positive regulation of binding; GO:0048598 embryonic morphogenesis; GO:0007399 nervous system development; GO:0052548 regulation of endopeptidase activity; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0048259 regulation of receptor-mediated endocytosis; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0090287 regulation of cellular response to growth factor stimulus; GO:0051272 positive regulation of cellular component movement; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0010811 positive regulation of cell-substrate adhesion; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0048513 animal organ development; GO:0042063 gliogenesis; GO:0051336 regulation of hydrolase activity; GO:0007417 central nervous system development; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0010604 positive regulation of macromolecule metabolic process; GO:0002682 regulation of immune system process; GO:1903317 regulation of protein maturation; GO:1903036 positive regulation of response to wounding; GO:0050794 regulation of cellular process; GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation; GO:0030449 regulation of complement activation; GO:0044707 single-multicellular organism process; GO:2000257 regulation of protein activation cascade; GO:0010951 negative regulation of endopeptidase activity; GO:0031399 regulation of protein modification process; GO:0030193 regulation of blood coagulation; GO:0002920 regulation of humoral immune response; GO:2000147 positive regulation of cell motility; GO:0048519 negative regulation of biological process; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0051239 regulation of multicellular organismal process; GO:1900047 negative regulation of hemostasis; GO:0009653 anatomical structure morphogenesis; GO:2000145 regulation of cell motility; GO:0043062 extracellular structure organization; GO:0061008 hepaticobiliary system development; GO:0006898 receptor-mediated endocytosis; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0006461 protein complex assembly; GO:0045861 negative regulation of proteolysis; GO:0030100 regulation of endocytosis; GO:0045785 positive regulation of cell adhesion; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0030334 regulation of cell migration; GO:0032101 regulation of response to external stimulus; GO:0030162 regulation of proteolysis; GO:0009892 negative regulation of metabolic process; GO:0030155 regulation of cell adhesion; GO:0014911 positive regulation of smooth muscle cell migration; GO:0030195 negative regulation of blood coagulation; GO:0001889 liver development; GO:0051247 positive regulation of protein metabolic process; GO:0061041 regulation of wound healing; GO:0031325 positive regulation of cellular metabolic process; GO:0070613 regulation of protein processing; GO:0006955 immune response; GO:0010810 regulation of cell-substrate adhesion; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:1903034 regulation of response to wounding; GO:0050819 negative regulation of coagulation; GO:0031100 animal organ regeneration; GO:0040017 positive regulation of locomotion; GO:0033627 cell adhesion mediated by integrin; GO:0023051 regulation of signaling; GO:0032092 positive regulation of protein binding; GO:0048869 cellular developmental process; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0010646 regulation of cell communication; GO:0022607 cellular component assembly; GO:0009893 positive regulation of metabolic process; GO:1900046 regulation of hemostasis; GO:0030198 extracellular matrix organization; GO:0002697 regulation of immune effector process; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0071822 protein complex subunit organization; GO:0045937 positive regulation of phosphate metabolic process; GO:0009888 tissue development; GO:0001704 formation of primary germ layer; GO:0051098 regulation of binding; GO:0048522 positive regulation of cellular process; GO:0010605 negative regulation of macromolecule metabolic process; GO:1903035 negative regulation of response to wounding; GO:0051050 positive regulation of transport; GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0051258 protein polymerization; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0070271 protein complex biogenesis; GO:0052547 regulation of peptidase activity; GO:0048856 anatomical structure development; GO:0048260 positive regulation of receptor-mediated endocytosis; GO:0016043 cellular component organization; GO:0097421 liver regeneration; GO:0050730 regulation of peptidyl-tyrosine phosphorylation; GO:0045807 positive regulation of endocytosis; GO:0060255 regulation of macromolecule metabolic process; GO:0002673 regulation of acute inflammatory response; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0051346 negative regulation of hydrolase activity; GO:0007369 gastrulation; GO:0043393 regulation of protein binding; GO:0030154 cell differentiation; GO:0023056 positive regulation of signaling; GO:0061302 smooth muscle cell-matrix adhesion; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:0043623 cellular protein complex assembly; GO:0034622 cellular macromolecular complex assembly; GO:0050878 regulation of body fluid levels; GO:0001706 endoderm formation; GO:0035987 endodermal cell differentiation; GO:0051049 regulation of transport; GO:0001932 regulation of protein phosphorylation; GO:0031401 positive regulation of protein modification process; GO:0048585 negative regulation of response to stimulus; GO:0001934 positive regulation of protein phosphorylation; GO:0006897 endocytosis; GO:0061045 negative regulation of wound healing; GO:0048518 positive regulation of biological process; GO:0043933 macromolecular complex subunit organization; GO:0050818 regulation of coagulation; GO:0010001 glial cell differentiation; GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway; GO:0031589 cell-substrate adhesion; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0050727 regulation of inflammatory response; GO:0051248 negative regulation of protein metabolic process; GO:0051128 regulation of cellular component organization; GO:0009967 positive regulation of signal transduction; GO:0040012 regulation of locomotion; GO:0031099 regeneration; GO:0014910 regulation of smooth muscle cell migration; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044420 extracellular matrix component; GO:0044422 organelle part; GO:0005604 basement membrane; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0043227 membrane-bounded organelle; GO:0048237 rough endoplasmic reticulum lumen; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005788 endoplasmic reticulum lumen; GO:0005791 rough endoplasmic reticulum; GO:0098797 plasma membrane protein complex; GO:0044446 intracellular organelle part; GO:0005796 Golgi lumen; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0031012 extracellular matrix; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0072562 blood microparticle; GO:0044459 plasma membrane part; GO:0044432 endoplasmic reticulum part; GO:0005578 proteinaceous extracellular matrix; GO:0043234 protein complex; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0071062 alphav-beta3 integrin-vitronectin complex; ","GO:0005102 receptor binding; GO:0043167 ion binding; GO:0044877 macromolecular complex binding; GO:0038024 cargo receptor activity; GO:0005044 scavenger receptor activity; GO:0005515 protein binding; GO:0005178 integrin binding; GO:0008201 heparin binding; GO:1901681 sulfur compound binding; GO:0050840 extracellular matrix binding; GO:0050839 cell adhesion molecule binding; GO:0060089 molecular transducer activity; GO:0097367 carbohydrate derivative binding; GO:0030247 polysaccharide binding; GO:0042802 identical protein binding; GO:0004872 receptor activity; GO:0005488 binding; GO:0030246 carbohydrate binding; GO:0005518 collagen binding; GO:0043168 anion binding; GO:0001871 pattern binding; GO:0005539 glycosaminoglycan binding; GO:0032403 protein complex binding; ","K06251","VTN; vitronectin","hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa04610 Complement and coagulation cascades - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa04512 ECM-receptor interaction - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); ","IPR000585; IPR020436; IPR001212; ","\"Hemopexin-like domain; Somatomedin B, chordata; Somatomedin B domain; \"\r"]
["P04040","Catalase OS=Homo sapiens OX=9606 GN=CAT","CAT",59.755,193.03,45.4,24,48,24,0.962,1.004,1.007,0.994,1.011,1.017,1.016,0.368,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0001649 osteoblast differentiation; GO:0010941 regulation of cell death; GO:0045321 leukocyte activation; GO:0006066 alcohol metabolic process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0032088 negative regulation of NF-kappaB transcription factor activity; GO:0033189 response to vitamin A; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0006195 purine nucleotide catabolic process; GO:0065003 macromolecular complex assembly; GO:0006639 acylglycerol metabolic process; GO:0044093 positive regulation of molecular function; GO:0009719 response to endogenous stimulus; GO:0070848 response to growth factor; GO:0009743 response to carbohydrate; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0098869 cellular oxidant detoxification; GO:1901652 response to peptide; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0051716 cellular response to stimulus; GO:0014070 response to organic cyclic compound; GO:0002443 leukocyte mediated immunity; GO:0080090 regulation of primary metabolic process; GO:0001503 ossification; GO:0000302 response to reactive oxygen species; GO:0009166 nucleotide catabolic process; GO:0044281 small molecule metabolic process; GO:0008202 steroid metabolic process; GO:0044763 single-organism cellular process; GO:0072521 purine-containing compound metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:0009650 UV protection; GO:0019439 aromatic compound catabolic process; GO:1901575 organic substance catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0010243 response to organonitrogen compound; GO:0014823 response to activity; GO:0051092 positive regulation of NF-kappaB transcription factor activity; GO:0044710 single-organism metabolic process; GO:0051090 regulation of sequence-specific DNA binding transcription factor activity; GO:0034284 response to monosaccharide; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:1901698 response to nitrogen compound; GO:0060548 negative regulation of cell death; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0002283 neutrophil activation involved in immune response; GO:1901615 organic hydroxy compound metabolic process; GO:0051260 protein homooligomerization; GO:0009628 response to abiotic stimulus; GO:0043067 regulation of programmed cell death; GO:1901700 response to oxygen-containing compound; GO:0032355 response to estradiol; GO:0048523 negative regulation of cellular process; GO:0072523 purine-containing compound catabolic process; GO:0048519 negative regulation of biological process; GO:0016125 sterol metabolic process; GO:0033591 response to L-ascorbic acid; GO:0051259 protein oligomerization; GO:0042493 response to drug; GO:0044270 cellular nitrogen compound catabolic process; GO:0042743 hydrogen peroxide metabolic process; GO:1990748 cellular detoxification; GO:0014066 regulation of phosphatidylinositol 3-kinase signaling; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0070482 response to oxygen levels; GO:0044248 cellular catabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0034655 nucleobase-containing compound catabolic process; GO:0055093 response to hyperoxia; GO:0042744 hydrogen peroxide catabolic process; GO:0070542 response to fatty acid; GO:0009966 regulation of signal transduction; GO:0006461 protein complex assembly; GO:0006638 neutral lipid metabolic process; GO:0001822 kidney development; GO:0008203 cholesterol metabolic process; GO:1902531 regulation of intracellular signal transduction; GO:0009416 response to light stimulus; GO:0006950 response to stress; GO:0051781 positive regulation of cell division; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0097305 response to alcohol; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0007584 response to nutrient; GO:0002263 cell activation involved in immune response; GO:0006163 purine nucleotide metabolic process; GO:0014854 response to inactivity; GO:0045055 regulated exocytosis; GO:0006641 triglyceride metabolic process; GO:0006793 phosphorus metabolic process; GO:0042542 response to hydrogen peroxide; GO:0001775 cell activation; GO:0019637 organophosphate metabolic process; GO:0072073 kidney epithelium development; GO:0036293 response to decreased oxygen levels; GO:0051179 localization; GO:0006955 immune response; GO:0048584 positive regulation of response to stimulus; GO:0001657 ureteric bud development; GO:0006887 exocytosis; GO:1901564 organonitrogen compound metabolic process; GO:0001101 response to acid chemical; GO:0046486 glycerolipid metabolic process; GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:0009117 nucleotide metabolic process; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0071363 cellular response to growth factor stimulus; GO:0033197 response to vitamin E; GO:0006796 phosphate-containing compound metabolic process; GO:0001823 mesonephros development; GO:0051234 establishment of localization; GO:2001141 regulation of RNA biosynthetic process; GO:0010646 regulation of cell communication; GO:1901292 nucleoside phosphate catabolic process; GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling; GO:0022607 cellular component assembly; GO:0051262 protein tetramerization; GO:0006753 nucleoside phosphate metabolic process; GO:0006979 response to oxidative stress; GO:1901361 organic cyclic compound catabolic process; GO:0046686 response to cadmium ion; GO:0009314 response to radiation; GO:0010035 response to inorganic substance; GO:0009642 response to light intensity; GO:0070887 cellular response to chemical stimulus; GO:0033273 response to vitamin; GO:0002274 myeloid leukocyte activation; GO:0006629 lipid metabolic process; GO:0032502 developmental process; GO:0035295 tube development; GO:0060429 epithelium development; GO:0010468 regulation of gene expression; GO:0009888 tissue development; GO:0071822 protein complex subunit organization; GO:0031326 regulation of cellular biosynthetic process; GO:0055114 oxidation-reduction process; GO:0002446 neutrophil mediated immunity; GO:0009636 response to toxic substance; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity; GO:0002444 myeloid leukocyte mediated immunity; GO:0010038 response to metal ion; GO:0036296 response to increased oxygen levels; GO:0001655 urogenital system development; GO:0051302 regulation of cell division; GO:0032868 response to insulin; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0043434 response to peptide hormone; GO:0032940 secretion by cell; GO:0015980 energy derivation by oxidation of organic compounds; GO:0007568 aging; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0010288 response to lead ion; GO:0044092 negative regulation of molecular function; GO:0043299 leukocyte degranulation; GO:0072163 mesonephric epithelium development; GO:0070271 protein complex biogenesis; GO:0048856 anatomical structure development; GO:0098754 detoxification; GO:0020027 hemoglobin metabolic process; GO:0016043 cellular component organization; GO:0043069 negative regulation of programmed cell death; GO:0006725 cellular aromatic compound metabolic process; GO:0002252 immune effector process; GO:1902652 secondary alcohol metabolic process; GO:0080184 response to phenylpropanoid; GO:0046434 organophosphate catabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0045471 response to ethanol; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0071310 cellular response to organic substance; GO:0072001 renal system development; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0033993 response to lipid; GO:0009991 response to extracellular stimulus; GO:0051289 protein homotetramerization; GO:0030154 cell differentiation; GO:0072593 reactive oxygen species metabolic process; GO:0043066 negative regulation of apoptotic process; GO:0023056 positive regulation of signaling; GO:0001666 response to hypoxia; GO:0034641 cellular nitrogen compound metabolic process; GO:0036230 granulocyte activation; GO:0010647 positive regulation of cell communication; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0006355 regulation of transcription, DNA-templated; GO:0072164 mesonephric tubule development; GO:0010193 response to ozone; GO:0044712 single-organism catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0043312 neutrophil degranulation; GO:0045333 cellular respiration; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0043933 macromolecular complex subunit organization; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0009411 response to UV; GO:1901565 organonitrogen compound catabolic process; GO:0009060 aerobic respiration; GO:0044767 single-organism developmental process; GO:0009967 positive regulation of signal transduction; GO:0031667 response to nutrient levels; GO:0009725 response to hormone; GO:0009056 catabolic process; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; GO:0046700 heterocycle catabolic process; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044438 microbody part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0005778 peroxisomal membrane; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0044439 peroxisomal part; GO:0031967 organelle envelope; GO:0070161 anchoring junction; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0005758 mitochondrial intermembrane space; GO:0031975 envelope; GO:0005773 vacuole; GO:0043230 extracellular organelle; GO:0034774 secretory granule lumen; GO:0005615 extracellular space; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0031974 membrane-enclosed lumen; GO:0005740 mitochondrial envelope; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0031970 organelle envelope lumen; GO:0005782 peroxisomal matrix; GO:0044464 cell part; GO:0098805 whole membrane; GO:0042579 microbody; GO:1903561 extracellular vesicle; GO:0005912 adherens junction; GO:0030141 secretory granule; GO:0031903 microbody membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0044429 mitochondrial part; GO:0005777 peroxisome; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0043226 organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0031907 microbody lumen; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0005102 receptor binding; GO:0043167 ion binding; GO:0046983 protein dimerization activity; GO:0016209 antioxidant activity; GO:0004096 catalase activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0004046 aminoacylase activity; GO:0048037 cofactor binding; GO:0016491 oxidoreductase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0020037 heme binding; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0042803 protein homodimerization activity; GO:0050661 NADP binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0004601 peroxidase activity; GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; GO:0046906 tetrapyrrole binding; GO:0019899 enzyme binding; GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; GO:0036094 small molecule binding; GO:0050662 coenzyme binding; GO:0016684 oxidoreductase activity, acting on peroxide as acceptor; ","K03781","katE; catalase [EC:1.11.1.6]","hsa05014 Amyotrophic lateral sclerosis (ALS) - Homo sapiens (human); hsa04211 Longevity regulating pathway - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); hsa00630 Glyoxylate and dicarboxylate metabolism - Homo sapiens (human); hsa04146 Peroxisome - Homo sapiens (human); hsa04068 FoxO signaling pathway - Homo sapiens (human); hsa00380 Tryptophan metabolism - Homo sapiens (human); hsa04213 Longevity regulating pathway - multiple species - Homo sapiens (human); ","IPR020835; IPR011614; IPR010582; ","Catalase-like domain; Catalase core domain; Catalase immune-responsive domain; \r"]
["P04062","Glucosylceramidase OS=Homo sapiens OX=9606 GN=GBA","GBA",59.716,21.963,16.6,10,13,10,1.015,1.112,0.852,1.042,0.95,1.043,1.019,0.792,"extracellular\r","GO:0051971 positive regulation of transmission of nerve impulse; GO:1905037 autophagosome organization; GO:0010941 regulation of cell death; GO:0006066 alcohol metabolic process; GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0006672 ceramide metabolic process; GO:0009891 positive regulation of biosynthetic process; GO:0044255 cellular lipid metabolic process; GO:0031347 regulation of defense response; GO:0006914 autophagy; GO:0010821 regulation of mitochondrion organization; GO:0044237 cellular metabolic process; GO:0008610 lipid biosynthetic process; GO:1903364 positive regulation of cellular protein catabolic process; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0008152 metabolic process; GO:0044057 regulation of system process; GO:0031333 negative regulation of protein complex assembly; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0043588 skin development; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0046514 ceramide catabolic process; GO:0005975 carbohydrate metabolic process; GO:0043086 negative regulation of catalytic activity; GO:0010506 regulation of autophagy; GO:0016241 regulation of macroautophagy; GO:1901575 organic substance catabolic process; GO:0030104 water homeostasis; GO:1902532 negative regulation of intracellular signal transduction; GO:0035304 regulation of protein dephosphorylation; GO:0061136 regulation of proteasomal protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0060548 negative regulation of cell death; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0043589 skin morphogenesis; GO:0044707 single-multicellular organism process; GO:0009267 cellular response to starvation; GO:0043407 negative regulation of MAP kinase activity; GO:0050728 negative regulation of inflammatory response; GO:1901700 response to oxygen-containing compound; GO:0048519 negative regulation of biological process; GO:0009653 anatomical structure morphogenesis; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0009889 regulation of biosynthetic process; GO:0009896 positive regulation of catabolic process; GO:0044248 cellular catabolic process; GO:0042176 regulation of protein catabolic process; GO:0048878 chemical homeostasis; GO:0050746 regulation of lipoprotein metabolic process; GO:1901215 negative regulation of neuron death; GO:0044711 single-organism biosynthetic process; GO:0034312 diol biosynthetic process; GO:0006950 response to stress; GO:0046165 alcohol biosynthetic process; GO:0032462 regulation of protein homooligomerization; GO:0032101 regulation of response to external stimulus; GO:0010033 response to organic substance; GO:1901576 organic substance biosynthetic process; GO:0019751 polyol metabolic process; GO:0050891 multicellular organismal water homeostasis; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0044283 small molecule biosynthetic process; GO:0045936 negative regulation of phosphate metabolic process; GO:0046513 ceramide biosynthetic process; GO:1905165 regulation of lysosomal protein catabolic process; GO:0034311 diol metabolic process; GO:0009968 negative regulation of signal transduction; GO:0043627 response to estrogen; GO:0023051 regulation of signaling; GO:0031331 positive regulation of cellular catabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0031400 negative regulation of protein modification process; GO:0009893 positive regulation of metabolic process; GO:0098908 regulation of neuronal action potential; GO:0031644 regulation of neurological system process; GO:0097066 response to thyroid hormone; GO:0006665 sphingolipid metabolic process; GO:0034612 response to tumor necrosis factor; GO:0006629 lipid metabolic process; GO:0016236 macroautophagy; GO:0006670 sphingosine metabolic process; GO:0006678 glucosylceramide metabolic process; GO:0045937 positive regulation of phosphate metabolic process; GO:0031326 regulation of cellular biosynthetic process; GO:0034097 response to cytokine; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051969 regulation of transmission of nerve impulse; GO:0010638 positive regulation of organelle organization; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0043549 regulation of kinase activity; GO:0016043 cellular component organization; GO:1903509 liposaccharide metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:1901566 organonitrogen compound biosynthetic process; GO:0031669 cellular response to nutrient levels; GO:0030149 sphingolipid catabolic process; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0033993 response to lipid; GO:0009268 response to pH; GO:0045862 positive regulation of proteolysis; GO:1904925 positive regulation of mitophagy in response to mitochondrial depolarization; GO:0043408 regulation of MAPK cascade; GO:0023056 positive regulation of signaling; GO:0045760 positive regulation of action potential; GO:0031960 response to corticosteroid; GO:0034641 cellular nitrogen compound metabolic process; GO:0010647 positive regulation of cell communication; GO:0046467 membrane lipid biosynthetic process; GO:0031348 negative regulation of defense response; GO:0050878 regulation of body fluid levels; GO:1901800 positive regulation of proteasomal protein catabolic process; GO:0001932 regulation of protein phosphorylation; GO:0033043 regulation of organelle organization; GO:0044249 cellular biosynthetic process; GO:0010822 positive regulation of mitochondrion organization; GO:1901565 organonitrogen compound catabolic process; GO:0046512 sphingosine biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0032463 negative regulation of protein homooligomerization; GO:0010563 negative regulation of phosphorus metabolic process; GO:0050727 regulation of inflammatory response; GO:0051248 negative regulation of protein metabolic process; GO:0001817 regulation of cytokine production; GO:0046173 polyol biosynthetic process; GO:0042594 response to starvation; GO:0043604 amide biosynthetic process; GO:0033561 regulation of water loss via skin; GO:0009056 catabolic process; GO:1901654 response to ketone; GO:0071840 cellular component organization or biogenesis; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0043243 positive regulation of protein complex disassembly; GO:0071345 cellular response to cytokine stimulus; GO:0032459 regulation of protein oligomerization; GO:0009605 response to external stimulus; GO:0098900 regulation of action potential; GO:0030148 sphingolipid biosynthetic process; GO:0051240 positive regulation of multicellular organismal process; GO:0032102 negative regulation of response to external stimulus; GO:0048545 response to steroid hormone; GO:0009719 response to endogenous stimulus; GO:0010562 positive regulation of phosphorus metabolic process; GO:1903362 regulation of cellular protein catabolic process; GO:0014070 response to organic cyclic compound; GO:0051174 regulation of phosphorus metabolic process; GO:1903599 positive regulation of mitophagy; GO:0032460 negative regulation of protein oligomerization; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0044281 small molecule metabolic process; GO:1904923 regulation of mitophagy in response to mitochondrial depolarization; GO:1901617 organic hydroxy compound biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0048513 animal organ development; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0044710 single-organism metabolic process; GO:0010508 positive regulation of autophagy; GO:0009887 animal organ morphogenesis; GO:0010604 positive regulation of macromolecule metabolic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:1901615 organic hydroxy compound metabolic process; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0097164 ammonium ion metabolic process; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:0006677 glycosylceramide metabolic process; GO:0051239 regulation of multicellular organismal process; GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0046520 sphingoid biosynthetic process; GO:0051338 regulation of transferase activity; GO:1901135 carbohydrate derivative metabolic process; GO:0001933 negative regulation of protein phosphorylation; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:0016042 lipid catabolic process; GO:1902531 regulation of intracellular signal transduction; GO:0048731 system development; GO:0032675 regulation of interleukin-6 production; GO:1901136 carbohydrate derivative catabolic process; GO:0071496 cellular response to external stimulus; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0031668 cellular response to extracellular stimulus; GO:0051247 positive regulation of protein metabolic process; GO:0043409 negative regulation of MAPK cascade; GO:0044242 cellular lipid catabolic process; GO:0046479 glycosphingolipid catabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0046477 glycosylceramide catabolic process; GO:0032715 negative regulation of interleukin-6 production; GO:0019377 glycolipid catabolic process; GO:0006643 membrane lipid metabolic process; GO:1903061 positive regulation of protein lipidation; GO:0051129 negative regulation of cellular component organization; GO:0051241 negative regulation of multicellular organismal process; GO:0001818 negative regulation of cytokine production; GO:0048871 multicellular organismal homeostasis; GO:0051130 positive regulation of cellular component organization; GO:1903059 regulation of protein lipidation; GO:0010646 regulation of cell communication; GO:0071901 negative regulation of protein serine/threonine kinase activity; GO:0007154 cell communication; GO:0033673 negative regulation of kinase activity; GO:0035303 regulation of dephosphorylation; GO:0007033 vacuole organization; GO:0050747 positive regulation of lipoprotein metabolic process; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0046466 membrane lipid catabolic process; GO:0006664 glycolipid metabolic process; GO:0048522 positive regulation of cellular process; GO:0023021 termination of signal transduction; GO:0033574 response to testosterone; GO:0043603 cellular amide metabolic process; GO:0051348 negative regulation of transferase activity; GO:0051384 response to glucocorticoid; GO:0042391 regulation of membrane potential; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0043254 regulation of protein complex assembly; GO:0035306 positive regulation of dephosphorylation; GO:0006469 negative regulation of protein kinase activity; GO:0019222 regulation of metabolic process; GO:0043244 regulation of protein complex disassembly; GO:0019220 regulation of phosphate metabolic process; GO:0006680 glucosylceramide catabolic process; GO:0048856 anatomical structure development; GO:0045859 regulation of protein kinase activity; GO:0071356 cellular response to tumor necrosis factor; GO:0043405 regulation of MAP kinase activity; GO:0006687 glycosphingolipid metabolic process; GO:0044087 regulation of cellular component biogenesis; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0009991 response to extracellular stimulus; GO:0042326 negative regulation of phosphorylation; GO:0009987 cellular process; GO:0098780 response to mitochondrial depolarisation; GO:1901214 regulation of neuron death; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0046519 sphingoid metabolic process; GO:0035307 positive regulation of protein dephosphorylation; GO:0044712 single-organism catabolic process; GO:0031401 positive regulation of protein modification process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0048518 positive regulation of biological process; GO:1904457 positive regulation of neuronal action potential; GO:1904350 regulation of protein catabolic process in the vacuole; GO:0031646 positive regulation of neurological system process; GO:1903146 regulation of mitophagy; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0051128 regulation of cellular component organization; GO:0031667 response to nutrient levels; GO:0045732 positive regulation of protein catabolic process; GO:0009725 response to hormone; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0031974 membrane-enclosed lumen; GO:0005765 lysosomal membrane; GO:0070062 extracellular exosome; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0005576 extracellular region; GO:0043202 lysosomal lumen; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0003824 catalytic activity; GO:0005102 receptor binding; GO:0005488 binding; GO:0016798 hydrolase activity, acting on glycosyl bonds; GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0004348 glucosylceramidase activity; ","K01201","GBA; glucosylceramidase [EC:3.2.1.45]","hsa04142 Lysosome - Homo sapiens (human); hsa00511 Other glycan degradation - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00600 Sphingolipid metabolism - Homo sapiens (human); ","IPR013780; IPR033453; IPR033452; IPR017853; IPR013781; ","\"Glycosyl hydrolase, all-beta; Glycosyl hydrolase family 30, TIM-barrel domain; Glycosyl hydrolase family 30, beta sandwich domain; Glycoside hydrolase superfamily; Glycoside hydrolase, catalytic domain; \"\r"]
["P04066","Tissue alpha-L-fucosidase OS=Homo sapiens OX=9606 GN=FUCA1","FUCA1",53.688,21.358,5.4,2,3,2,1.086,1.086,1.186,0.977,0.83,0.86,0.794,0.0157,"extracellular\r","GO:0045321 leukocyte activation; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0006026 aminoglycan catabolic process; GO:0044699 single-organism process; GO:0016139 glycoside catabolic process; GO:0050896 response to stimulus; GO:0030203 glycosaminoglycan metabolic process; GO:0051234 establishment of localization; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0005996 monosaccharide metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0043170 macromolecule metabolic process; GO:0036230 granulocyte activation; GO:0016137 glycoside metabolic process; GO:0006022 aminoglycan metabolic process; GO:0009987 cellular process; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0002443 leukocyte mediated immunity; GO:0044712 single-organism catabolic process; GO:0044281 small molecule metabolic process; GO:0016192 vesicle-mediated transport; GO:0002446 neutrophil mediated immunity; GO:1901658 glycosyl compound catabolic process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:1901136 carbohydrate derivative catabolic process; GO:0002376 immune system process; GO:0005975 carbohydrate metabolic process; GO:0044238 primary metabolic process; GO:0043312 neutrophil degranulation; GO:0006004 fucose metabolic process; GO:0002263 cell activation involved in immune response; GO:0006027 glycosaminoglycan catabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0006810 transport; GO:0002366 leukocyte activation involved in immune response; GO:0044723 single-organism carbohydrate metabolic process; GO:1901575 organic substance catabolic process; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:1901565 organonitrogen compound catabolic process; GO:0032940 secretion by cell; GO:0044710 single-organism metabolic process; GO:0009057 macromolecule catabolic process; GO:0001775 cell activation; GO:0043299 leukocyte degranulation; GO:1901657 glycosyl compound metabolic process; GO:0051179 localization; GO:0006955 immune response; GO:0009056 catabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0019318 hexose metabolic process; GO:0006887 exocytosis; ","GO:0034774 secretory granule lumen; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0043202 lysosomal lumen; GO:0005576 extracellular region; GO:0042582 azurophil granule; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds; GO:0016787 hydrolase activity; GO:0003824 catalytic activity; GO:0015928 fucosidase activity; GO:0004560 alpha-L-fucosidase activity; GO:0016798 hydrolase activity, acting on glycosyl bonds; ","K01206","FUCA; alpha-L-fucosidase [EC:3.2.1.51]","hsa04142 Lysosome - Homo sapiens (human); hsa00511 Other glycan degradation - Homo sapiens (human); ","IPR013780; IPR017853; IPR031919; IPR013781; ","\"Glycosyl hydrolase, all-beta; Glycoside hydrolase superfamily; Alpha-L-fucosidase, C-terminal; Glycoside hydrolase, catalytic domain; \"\r"]
["P04075","Fructose-bisphosphate aldolase A OS=Homo sapiens OX=9606 GN=ALDOA","ALDOA",39.42,288.8,71.7,25,70,19,0.962,0.96,0.949,1.016,1.066,1.013,1.078,0.0118,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0009116 nucleoside metabolic process; GO:0045321 leukocyte activation; GO:0006165 nucleoside diphosphate phosphorylation; GO:0019362 pyridine nucleotide metabolic process; GO:0006096 glycolytic process; GO:0009163 nucleoside biosynthetic process; GO:0046129 purine ribonucleoside biosynthetic process; GO:0009185 ribonucleoside diphosphate metabolic process; GO:0044237 cellular metabolic process; GO:0006006 glucose metabolic process; GO:0046390 ribose phosphate biosynthetic process; GO:0030036 actin cytoskeleton organization; GO:0008152 metabolic process; GO:0006094 gluconeogenesis; GO:1901137 carbohydrate derivative biosynthetic process; GO:0006091 generation of precursor metabolites and energy; GO:0008360 regulation of cell shape; GO:0065003 macromolecular complex assembly; GO:0032787 monocarboxylic acid metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0009145 purine nucleoside triphosphate biosynthetic process; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0002443 leukocyte mediated immunity; GO:0018130 heterocycle biosynthetic process; GO:0009179 purine ribonucleoside diphosphate metabolic process; GO:0009206 purine ribonucleoside triphosphate biosynthetic process; GO:0044281 small molecule metabolic process; GO:0006754 ATP biosynthetic process; GO:0044763 single-organism cellular process; GO:0006941 striated muscle contraction; GO:0061620 glycolytic process through glucose-6-phosphate; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0006732 coenzyme metabolic process; GO:0005975 carbohydrate metabolic process; GO:0032501 multicellular organismal process; GO:0061718 glucose catabolic process to pyruvate; GO:0009168 purine ribonucleoside monophosphate biosynthetic process; GO:0090407 organophosphate biosynthetic process; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0006000 fructose metabolic process; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0019674 NAD metabolic process; GO:0044710 single-organism metabolic process; GO:0046716 muscle cell cellular homeostasis; GO:0009126 purine nucleoside monophosphate metabolic process; GO:0006164 purine nucleotide biosynthetic process; GO:0097435 supramolecular fiber organization; GO:1901362 organic cyclic compound biosynthetic process; GO:0043436 oxoacid metabolic process; GO:0030388 fructose 1,6-bisphosphate metabolic process; GO:0009201 ribonucleoside triphosphate biosynthetic process; GO:0050794 regulation of cellular process; GO:0016310 phosphorylation; GO:0002283 neutrophil activation involved in immune response; GO:0051260 protein homooligomerization; GO:0046496 nicotinamide nucleotide metabolic process; GO:0009259 ribonucleotide metabolic process; GO:0002576 platelet degranulation; GO:0046364 monosaccharide biosynthetic process; GO:0006735 NADH regeneration; GO:0060249 anatomical structure homeostasis; GO:0051259 protein oligomerization; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0007010 cytoskeleton organization; GO:0009119 ribonucleoside metabolic process; GO:0006461 protein complex assembly; GO:0044711 single-organism biosynthetic process; GO:0016192 vesicle-mediated transport; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0002376 immune system process; GO:0009141 nucleoside triphosphate metabolic process; GO:0042455 ribonucleoside biosynthetic process; GO:0044238 primary metabolic process; GO:0002263 cell activation involved in immune response; GO:1901576 organic substance biosynthetic process; GO:0006163 purine nucleotide metabolic process; GO:0045055 regulated exocytosis; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0009260 ribonucleotide biosynthetic process; GO:0044283 small molecule biosynthetic process; GO:0001775 cell activation; GO:0019637 organophosphate metabolic process; GO:0019320 hexose catabolic process; GO:0006955 immune response; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0019318 hexose metabolic process; GO:0006887 exocytosis; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0006757 ATP generation from ADP; GO:0046365 monosaccharide catabolic process; GO:0003012 muscle system process; GO:0042278 purine nucleoside metabolic process; GO:0046031 ADP metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0019319 hexose biosynthetic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0046939 nucleotide phosphorylation; GO:0009156 ribonucleoside monophosphate biosynthetic process; GO:0009135 purine nucleoside diphosphate metabolic process; GO:0072524 pyridine-containing compound metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0061615 glycolytic process through fructose-6-phosphate; GO:0051234 establishment of localization; GO:0051262 protein tetramerization; GO:0022607 cellular component assembly; GO:0006753 nucleoside phosphate metabolic process; GO:0002274 myeloid leukocyte activation; GO:0071822 protein complex subunit organization; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0055114 oxidation-reduction process; GO:0002446 neutrophil mediated immunity; GO:0019725 cellular homeostasis; GO:1901360 organic cyclic compound metabolic process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0042451 purine nucleoside biosynthetic process; GO:0051186 cofactor metabolic process; GO:0016052 carbohydrate catabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0072522 purine-containing compound biosynthetic process; GO:0032940 secretion by cell; GO:0043299 leukocyte degranulation; GO:1901657 glycosyl compound metabolic process; GO:0006082 organic acid metabolic process; GO:0070271 protein complex biogenesis; GO:0016043 cellular component organization; GO:0016051 carbohydrate biosynthetic process; GO:0009165 nucleotide biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0002252 immune effector process; GO:0009142 nucleoside triphosphate biosynthetic process; GO:0006734 NADH metabolic process; GO:0007015 actin filament organization; GO:0050896 response to stimulus; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0061621 canonical glycolysis; GO:0042592 homeostatic process; GO:0006090 pyruvate metabolic process; GO:0051289 protein homotetramerization; GO:0006936 muscle contraction; GO:0005996 monosaccharide metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0036230 granulocyte activation; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0009132 nucleoside diphosphate metabolic process; GO:0046034 ATP metabolic process; GO:0009124 nucleoside monophosphate biosynthetic process; GO:0003008 system process; GO:0044724 single-organism carbohydrate catabolic process; GO:0044712 single-organism catabolic process; GO:0009127 purine nucleoside monophosphate biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0044282 small molecule catabolic process; GO:0043312 neutrophil degranulation; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0002366 leukocyte activation involved in immune response; GO:0046128 purine ribonucleoside metabolic process; GO:0042119 neutrophil activation; GO:0006007 glucose catabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0009152 purine ribonucleotide biosynthetic process; GO:1901659 glycosyl compound biosynthetic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0019752 carboxylic acid metabolic process; GO:0051128 regulation of cellular component organization; GO:0009150 purine ribonucleotide metabolic process; GO:0022604 regulation of cell morphogenesis; GO:0009056 catabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0034774 secretory granule lumen; GO:1904724 tertiary granule lumen; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0030016 myofibril; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0031674 I band; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0043292 contractile fiber; GO:0030141 secretory granule; GO:0031430 M band; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0070820 tertiary granule; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0015629 actin cytoskeleton; GO:0005576 extracellular region; GO:0099081 supramolecular polymer; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0031672 A band; GO:0030017 sarcomere; GO:0031093 platelet alpha granule lumen; GO:0044449 contractile fiber part; GO:0031091 platelet alpha granule; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0003723 RNA binding; GO:0015631 tubulin binding; GO:0016829 lyase activity; GO:0005515 protein binding; GO:0048029 monosaccharide binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0050839 cell adhesion molecule binding; GO:0042802 identical protein binding; GO:0008092 cytoskeletal protein binding; GO:0004332 fructose-bisphosphate aldolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016830 carbon-carbon lyase activity; GO:0003676 nucleic acid binding; GO:0045296 cadherin binding; GO:0003779 actin binding; GO:0070061 fructose binding; GO:0030246 carbohydrate binding; GO:0016832 aldehyde-lyase activity; GO:0036094 small molecule binding; ","K01623","ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]","hsa00051 Fructose and mannose metabolism - Homo sapiens (human); hsa04066 HIF-1 signaling pathway - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00030 Pentose phosphate pathway - Homo sapiens (human); hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human); hsa01230 Biosynthesis of amino acids - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); ","IPR013785; ","Aldolase-type TIM barrel; \r"]
["P04080","Cystatin-B OS=Homo sapiens OX=9606 GN=CSTB","CSTB",11.139,28.023,67.3,6,16,6,1.038,0.954,0.963,1.073,0.964,1.012,1.032,0.49,"cytoplasm\r","GO:0045321 leukocyte activation; GO:0044699 single-organism process; GO:0051234 establishment of localization; GO:0007610 behavior; GO:0010466 negative regulation of peptidase activity; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0052548 regulation of endopeptidase activity; GO:0002443 leukocyte mediated immunity; GO:0080090 regulation of primary metabolic process; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0031323 regulation of cellular metabolic process; GO:0043086 negative regulation of catalytic activity; GO:0032501 multicellular organismal process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0051336 regulation of hydrolase activity; GO:0032940 secretion by cell; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0043299 leukocyte degranulation; GO:0052547 regulation of peptidase activity; GO:0044708 single-organism behavior; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0010951 negative regulation of endopeptidase activity; GO:0002283 neutrophil activation involved in immune response; GO:0008344 adult locomotory behavior; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:0051346 negative regulation of hydrolase activity; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0036230 granulocyte activation; GO:0030534 adult behavior; GO:0009987 cellular process; GO:0045861 negative regulation of proteolysis; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0030162 regulation of proteolysis; GO:0043312 neutrophil degranulation; GO:0009892 negative regulation of metabolic process; GO:0002263 cell activation involved in immune response; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0051246 regulation of protein metabolic process; GO:0007626 locomotory behavior; GO:0051248 negative regulation of protein metabolic process; GO:0001775 cell activation; GO:0051179 localization; GO:0006955 immune response; GO:0006887 exocytosis; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:1904724 tertiary granule lumen; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0070820 tertiary granule; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0003723 RNA binding; GO:0061134 peptidase regulator activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0004857 enzyme inhibitor activity; GO:0004866 endopeptidase inhibitor activity; GO:0004869 cysteine-type endopeptidase inhibitor activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0002020 protease binding; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0030414 peptidase inhibitor activity; GO:0061135 endopeptidase regulator activity; GO:0019899 enzyme binding; ","K13907",null,null,"IPR000010; ","Cystatin domain; \r"]
["P04083","Annexin A1 OS=Homo sapiens OX=9606 GN=ANXA1","ANXA1",38.714,323.31,61,21,87,21,1.033,1.047,1.066,0.939,0.972,0.948,0.909,0.00224,"cytoplasm\r",{"$cut":{"chars":20708,"head":"GO:0044700 single organism signaling; GO:0002694 regulation of leukocyte activation; GO:0010941 regulation of cell death; GO:0048732 gland development; GO:0022414 reproductive process; GO:0002698 negative regulation of immune effector process; GO:0071384 cellular response to corticosteroid stimulus; GO:0009891 positive regulation of biosynthetic process; GO:0070555 response to interleukin-1; GO:0031347 regulation of defense response; GO:0031338 regulation of vesicle fusion; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0042110 T cell activation; GO:0009913 epidermal cell differentiation; GO:0008152 metabolic process; GO:0032946 positive regulation of mononuclear cell proliferation; GO:0015718 monocarboxylic acid transport; GO:0008360 regulation of cell shape; GO:1901990 regulation of mitotic cell cycle phase transition; GO:2000515 negative regulation of CD4-positive, alpha-beta T cell activation; GO:0043370 regulation of CD4-positive, alpha-beta T cell differentiation; GO:0009306 protein secretion; GO:0008544 epidermis development; GO:0045621 positive regulation of lymphocyte differentiation; GO:0090068 positive regulation of cell cycle process; GO:0042886 amide transport; GO:0046889 positive regulation of lipid biosynthetic process; GO:0051051 negative regulation of transport; GO:0046636 negative regulation of alpha-beta T cell activation; GO:0051716 cellular response to stimulus; GO:0043588 skin development; GO:0050709 negative regulation of protein secretion; GO:0080090 regulation of primary metabolic process; GO:1903038 negative regulation of leukocyte cell-cell adhesion; GO:0002790 peptide secretion; GO:0060191 regulation of lipase activity; GO:1903531 negative regulation of secretion by cell; GO:0044763 single-organism cellular process; GO:0002520 immune system development; GO:0048870 cell motility; GO:0043086 negative regulation of catalytic activity; GO:0006935 chemotaxis; GO:0071396 cellular response to lipid; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0030072 peptide hormone secretion; GO:0031532 actin cytoskeleton reorganization; GO:0071715 icosanoid transport; GO:0010243 response to organonitrogen compound; GO:0042063 gliogenesis; GO:0045931 positive regulation of mitotic cell cycle; GO:0007267 cell-cell signaling; GO:0046890 regulation of lipid biosynthetic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:1901698 response to nitrogen compound; GO:0042304 regulation of fatty acid biosynthetic process; GO:0051223 regulation of protein transport; GO:0060548 negative regulation of cell death; GO:0048609 multicellular organismal reproductive process; GO:0030855 epithelial cell differentiation; GO:0000003 reproduction; GO:0044707 single-multicellular organism process; GO:0032677 regulation of interleukin-8 production; GO:0000733 DNA strand renaturation; GO:0045580 regulation of T cell differentiation; GO:0001819 positive regulation of cytokine production; GO:0006259 DNA metabolic process; GO:0030850 prostate gland development; GO:0070459 prolactin secretion; GO:0018149 peptide cross-linking; GO:1901700 response to oxygen-containing compound; GO:0022408 negative regulation of cell-cell adhesion; GO:0017157 regulation of exocytosis; GO:0010517 regulation of phospholipase activity; GO:0048519 negative regulation of biological process; GO:1901989 positive regulation of cell cycle phase transition; GO:1903706 regulation of hemopoiesis; GO:0030098 lymphocyte differentiation; GO:0042493 response to drug; GO:0050867 positive regulation of cell activation; GO:0097530 granulocyte migration; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:2000145 regulation of cell motility; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:2000516 positive regulation of CD4-positive, alpha-beta T cell activation; GO:0061458 reproductive system development; GO:0050778 positive regulation of immune respons"}},"GO:0016020 membrane; GO:0044421 extracellular region part; GO:0009897 external side of plasma membrane; GO:0031090 organelle membrane; GO:0019898 extrinsic component of membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0005913 cell-cell adherens junction; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0098590 plasma membrane region; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0005764 lysosome; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0045177 apical part of cell; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0098552 side of membrane; GO:0005929 cilium; GO:0010008 endosome membrane; GO:0042995 cell projection; GO:0031232 extrinsic component of external side of plasma membrane; GO:0031967 organelle envelope; GO:0019897 extrinsic component of plasma membrane; GO:0070161 anchoring junction; GO:0012506 vesicle membrane; GO:0044440 endosomal part; GO:0031981 nuclear lumen; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0016328 lateral plasma membrane; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0031975 envelope; GO:0005773 vacuole; GO:0043234 protein complex; GO:0042383 sarcolemma; GO:0031966 mitochondrial membrane; GO:0043230 extracellular organelle; GO:0016323 basolateral plasma membrane; GO:0005615 extracellular space; GO:0016324 apical plasma membrane; GO:0031410 cytoplasmic vesicle; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005911 cell-cell junction; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0001891 phagocytic cup; GO:0042629 mast cell granule; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0031901 early endosome membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0044429 mitochondrial part; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0031514 motile cilium; GO:0005829 cytosol; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0001533 cornified envelope; GO:0031313 extrinsic component of endosome membrane; GO:0031312 extrinsic component of organelle membrane; GO:0009986 cell surface; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005102 receptor binding; GO:0046983 protein dimerization activity; GO:0004859 phospholipase inhibitor activity; GO:0003697 single-stranded DNA binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0048306 calcium-dependent protein binding; GO:0016887 ATPase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0098641 cadherin binding involved in cell-cell adhesion; GO:0042802 identical protein binding; GO:0016462 pyrophosphatase activity; GO:0033676 double-stranded DNA-dependent ATPase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0045296 cadherin binding; GO:0008289 lipid binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0008094 DNA-dependent ATPase activity; GO:0019834 phospholipase A2 inhibitor activity; GO:0003723 RNA binding; GO:0005544 calcium-dependent phospholipid binding; GO:0003677 DNA binding; GO:0030674 protein binding, bridging; GO:0055102 lipase inhibitor activity; GO:0097617 annealing activity; GO:0004386 helicase activity; GO:0043167 ion binding; GO:0036310 annealing helicase activity; GO:0098632 protein binding involved in cell-cell adhesion; GO:0017111 nucleoside-triphosphatase activity; GO:0003727 single-stranded RNA binding; GO:0050839 cell adhesion molecule binding; GO:0098631 protein binding involved in cell adhesion; GO:0030234 enzyme regulator activity; GO:0042803 protein homodimerization activity; GO:0042623 ATPase activity, coupled; GO:0003676 nucleic acid binding; GO:0005543 phospholipid binding; GO:0046872 metal ion binding; GO:0060090 binding, bridging; GO:0005509 calcium ion binding; GO:0005198 structural molecule activity; ","K17091"]
["P04114","Apolipoprotein B-100 OS=Homo sapiens OX=9606 GN=APOB","APOB",515.6,323.31,39.1,162,355,162,0.958,0.952,0.933,1.052,1.051,1.056,1.111,0.000201,"endoplasmic reticulum\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0010744 positive regulation of macrophage derived foam cell differentiation; GO:0065008 regulation of biological quality; GO:0022414 reproductive process; GO:0006066 alcohol metabolic process; GO:0043009 chordate embryonic development; GO:0034379 very-low-density lipoprotein particle assembly; GO:0044255 cellular lipid metabolic process; GO:0010886 positive regulation of cholesterol storage; GO:0019216 regulation of lipid metabolic process; GO:0031347 regulation of defense response; GO:0071345 cellular response to cytokine stimulus; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0042157 lipoprotein metabolic process; GO:0009607 response to biotic stimulus; GO:0046461 neutral lipid catabolic process; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0032879 regulation of localization; GO:0065003 macromolecular complex assembly; GO:0044702 single organism reproductive process; GO:0006639 acylglycerol metabolic process; GO:0071825 protein-lipid complex subunit organization; GO:0009719 response to endogenous stimulus; GO:0090181 regulation of cholesterol metabolic process; GO:0009743 response to carbohydrate; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0008104 protein localization; GO:0044419 interspecies interaction between organisms; GO:0009790 embryo development; GO:0055088 lipid homeostasis; GO:0044765 single-organism transport; GO:0007399 nervous system development; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0006869 lipid transport; GO:0080090 regulation of primary metabolic process; GO:0002758 innate immune response-activating signal transduction; GO:0071398 cellular response to fatty acid; GO:0044281 small molecule metabolic process; GO:0019953 sexual reproduction; GO:0008202 steroid metabolic process; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0048870 cell motility; GO:0032501 multicellular organismal process; GO:0071396 cellular response to lipid; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0050900 leukocyte migration; GO:0034377 plasma lipoprotein particle assembly; GO:0001701 in utero embryonic development; GO:0044710 single-organism metabolic process; GO:0030163 protein catabolic process; GO:0046890 regulation of lipid biosynthetic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0016101 diterpenoid metabolic process; GO:0048844 artery morphogenesis; GO:0002682 regulation of immune system process; GO:0048609 multicellular organismal reproductive process; GO:0051094 positive regulation of developmental process; GO:0046503 glycerolipid catabolic process; GO:0072359 circulatory system development; GO:0000003 reproduction; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:1901615 organic hydroxy compound metabolic process; GO:0044267 cellular protein metabolic process; GO:1901700 response to oxygen-containing compound; GO:0019218 regulation of steroid metabolic process; GO:0032355 response to estradiol; GO:0009791 post-embryonic development; GO:0080134 regulation of response to stress; GO:1902930 regulation of alcohol biosynthetic process; GO:0016125 sterol metabolic process; GO:0045597 positive regulation of cell differentiation; GO:0009653 anatomical structure morphogenesis; GO:0031349 positive regulation of defense response; GO:1902578 single-organism localization; GO:0071229 cellular response to acid chemical; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0034369 plasma lipoprotein particle remodeling; GO:0044248 cellular catabolic process; GO:0006898 receptor-mediated endocytosis; GO:0007275 multicellular organism development; GO:0070542 response to fatty acid; GO:0050778 positive regulation of immune response; GO:0048878 chemical homeostasis; GO:0009617 response to bacterium; GO:0016042 lipid catabolic process; GO:0002253 activation of immune response; GO:0006638 neutral lipid metabolic process; GO:0008203 cholesterol metabolic process; GO:0006720 isoprenoid metabolic process; GO:0032496 response to lipopolysaccharide; GO:0034694 response to prostaglandin; GO:0007283 spermatogenesis; GO:0048731 system development; GO:0010884 positive regulation of lipid storage; GO:0016192 vesicle-mediated transport; GO:0072358 cardiovascular system development; GO:0002376 immune system process; GO:0071702 organic substance transport; GO:0010876 lipid localization; GO:0034381 plasma lipoprotein particle clearance; GO:0010033 response to organic substance; GO:0010269 response to selenium ion; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0034383 low-density lipoprotein particle clearance; GO:0045184 establishment of protein localization; GO:0006641 triglyceride metabolic process; GO:0010883 regulation of lipid storage; GO:0061024 membrane organization; GO:0044242 cellular lipid catabolic process; GO:0006928 movement of cell or subcellular component; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0071379 cellular response to prostaglandin stimulus; GO:0034367 macromolecular complex remodeling; GO:0001101 response to acid chemical; GO:0015850 organic hydroxy compound transport; GO:0046486 glycerolipid metabolic process; GO:0051674 localization of cell; GO:0001568 blood vessel development; GO:0030301 cholesterol transport; GO:0033344 cholesterol efflux; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:0044872 lipoprotein localization; GO:0007154 cell communication; GO:0050810 regulation of steroid biosynthetic process; GO:0009893 positive regulation of metabolic process; GO:0022607 cellular component assembly; GO:0045088 regulation of innate immune response; GO:0002221 pattern recognition receptor signaling pathway; GO:0010035 response to inorganic substance; GO:0034612 response to tumor necrosis factor; GO:0048514 blood vessel morphogenesis; GO:0042159 lipoprotein catabolic process; GO:0033036 macromolecule localization; GO:0042158 lipoprotein biosynthetic process; GO:0070887 cellular response to chemical stimulus; GO:0006629 lipid metabolic process; GO:0071827 plasma lipoprotein particle organization; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0006642 triglyceride mobilization; GO:0034097 response to cytokine; GO:0002237 response to molecule of bacterial origin; GO:0010743 regulation of macrophage derived foam cell differentiation; GO:0001944 vasculature development; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0009566 fertilization; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0032870 cellular response to hormone stimulus; GO:0060840 artery development; GO:0002224 toll-like receptor signaling pathway; GO:0019222 regulation of metabolic process; GO:0065005 protein-lipid complex assembly; GO:0040011 locomotion; GO:0048856 anatomical structure development; GO:0009615 response to virus; GO:0015918 sterol transport; GO:0016043 cellular component organization; GO:0016477 cell migration; GO:0044257 cellular protein catabolic process; GO:0002218 activation of innate immune response; GO:0034374 low-density lipoprotein particle remodeling; GO:1902652 secondary alcohol metabolic process; GO:0071356 cellular response to tumor necrosis factor; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0046464 acylglycerol catabolic process; GO:0071704 organic substance metabolic process; GO:0097006 regulation of plasma lipoprotein particle levels; GO:0042592 homeostatic process; GO:0030317 flagellated sperm motility; GO:0033993 response to lipid; GO:0016032 viral process; GO:0001523 retinoid metabolic process; GO:0002757 immune response-activating signal transduction; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0019433 triglyceride catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0045089 positive regulation of innate immune response; GO:0048232 male gamete generation; GO:0097722 sperm motility; GO:0044712 single-organism catabolic process; GO:0045540 regulation of cholesterol biosynthetic process; GO:0009792 embryo development ending in birth or egg hatching; GO:0042632 cholesterol homeostasis; GO:0006897 endocytosis; GO:0042953 lipoprotein transport; GO:0048518 positive regulation of biological process; GO:0007276 gamete generation; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0032504 multicellular organism reproduction; GO:1901701 cellular response to oxygen-containing compound; GO:0010885 regulation of cholesterol storage; GO:0034645 cellular macromolecule biosynthetic process; GO:0071495 cellular response to endogenous stimulus; GO:0044767 single-organism developmental process; GO:0009057 macromolecule catabolic process; GO:0044703 multi-organism reproductive process; GO:0002684 positive regulation of immune system process; GO:0055092 sterol homeostasis; GO:0006721 terpenoid metabolic process; GO:0009725 response to hormone; GO:0034368 protein-lipid complex remodeling; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0045334 clathrin-coated endocytic vesicle; GO:0031090 organelle membrane; GO:0034362 low-density lipoprotein particle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0034385 triglyceride-rich plasma lipoprotein particle; GO:0043025 neuronal cell body; GO:0032991 macromolecular complex; GO:0005623 cell; GO:0034361 very-low-density lipoprotein particle; GO:0044422 organelle part; GO:0005769 early endosome; GO:0005775 vacuolar lumen; GO:0034360 chylomicron remnant; GO:0070062 extracellular exosome; GO:0030136 clathrin-coated vesicle; GO:0005622 intracellular; GO:0005764 lysosome; GO:1990777 lipoprotein particle; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0005789 endoplasmic reticulum membrane; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0010008 endosome membrane; GO:0030666 endocytic vesicle membrane; GO:0012506 vesicle membrane; GO:0044440 endosomal part; GO:0034363 intermediate-density lipoprotein particle; GO:0030135 coated vesicle; GO:0043202 lysosomal lumen; GO:0005576 extracellular region; GO:0031904 endosome lumen; GO:0005886 plasma membrane; GO:0070971 endoplasmic reticulum exit site; GO:0043231 intracellular membrane-bounded organelle; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043230 extracellular organelle; GO:0005790 smooth endoplasmic reticulum; GO:0005615 extracellular space; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0034358 plasma lipoprotein particle; GO:0031982 vesicle; GO:0030669 clathrin-coated endocytic vesicle membrane; GO:0044424 intracellular part; GO:0034359 mature chylomicron; GO:0030662 coated vesicle membrane; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0032994 protein-lipid complex; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0030139 endocytic vesicle; GO:0005788 endoplasmic reticulum lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0042627 chylomicron; GO:0005829 cytosol; GO:0030665 clathrin-coated vesicle membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0060205 cytoplasmic vesicle lumen; GO:0044432 endoplasmic reticulum part; GO:0044297 cell body; GO:0044444 cytoplasmic part; GO:0071682 endocytic vesicle lumen; ","GO:0035473 lipase binding; GO:0005102 receptor binding; GO:0043167 ion binding; GO:0005319 lipid transporter activity; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0008201 heparin binding; GO:1901681 sulfur compound binding; GO:0070325 lipoprotein particle receptor binding; GO:0097367 carbohydrate derivative binding; GO:0017127 cholesterol transporter activity; GO:0005488 binding; GO:0005543 phospholipid binding; GO:0015248 sterol transporter activity; GO:0008289 lipid binding; GO:0043168 anion binding; GO:0005539 glycosaminoglycan binding; GO:0050750 low-density lipoprotein particle receptor binding; GO:0019899 enzyme binding; GO:0005215 transporter activity; ","K14462","APOB; apolipoprotein B","hsa04975 Fat digestion and absorption - Homo sapiens (human); hsa04977 Vitamin digestion and absorption - Homo sapiens (human); hsa04979 Cholesterol metabolism - Homo sapiens (human); ","IPR011030; IPR015818; IPR015817; IPR001747; IPR022176; IPR015816; IPR015819; IPR016024; IPR015255; IPR009454; ","\"Vitellinogen, superhelical; Vitellinogen, open beta-sheet, subdomain 2; Vitellinogen, open beta-sheet, subdomain 1; Lipid transport protein, N-terminal; Apolipoprotein B100 C-terminal; Vitellinogen, beta-sheet N-terminal; Lipid transport protein, beta-sheet shell; Armadillo-type fold; Vitellinogen, open beta-sheet; Lipid transport, open beta-sheet; \"\r"]
["P04156","Major prion protein OS=Homo sapiens OX=9606 GN=PRNP","PRNP",27.661,5.0998,13,3,3,3,1.067,1.002,1.12,0.931,1.078,0.817,0.886,0.217,"extracellular\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:1900271 regulation of long-term synaptic potentiation; GO:0002694 regulation of leukocyte activation; GO:0050672 negative regulation of lymphocyte proliferation; GO:0065008 regulation of biological quality; GO:0010941 regulation of cell death; GO:0032944 regulation of mononuclear cell proliferation; GO:0032270 positive regulation of cellular protein metabolic process; GO:1903533 regulation of protein targeting; GO:1904645 response to beta-amyloid; GO:0050877 neurological system process; GO:0008285 negative regulation of cell proliferation; GO:0007610 behavior; GO:0008152 metabolic process; GO:0070664 negative regulation of leukocyte proliferation; GO:0032879 regulation of localization; GO:0065003 macromolecular complex assembly; GO:1905664 regulation of calcium ion import across plasma membrane; GO:0055065 metal ion homeostasis; GO:0009719 response to endogenous stimulus; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0090314 positive regulation of protein targeting to membrane; GO:1901652 response to peptide; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0006878 cellular copper ion homeostasis; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:1903038 negative regulation of leukocyte cell-cell adhesion; GO:0044763 single-organism cellular process; GO:0043269 regulation of ion transport; GO:0046006 regulation of activated T cell proliferation; GO:0050670 regulation of lymphocyte proliferation; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0046916 cellular transition metal ion homeostasis; GO:0050776 regulation of immune response; GO:0034762 regulation of transmembrane transport; GO:1903506 regulation of nucleic acid-templated transcription; GO:0010243 response to organonitrogen compound; GO:1902532 negative regulation of intracellular signal transduction; GO:0032269 negative regulation of cellular protein metabolic process; GO:0051090 regulation of sequence-specific DNA binding transcription factor activity; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0032700 negative regulation of interleukin-17 production; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051223 regulation of protein transport; GO:0002682 regulation of immune system process; GO:0060548 negative regulation of cell death; GO:0044708 single-organism behavior; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation; GO:0044707 single-multicellular organism process; GO:0055076 transition metal ion homeostasis; GO:0007162 negative regulation of cell adhesion; GO:0042127 regulation of cell proliferation; GO:0051260 protein homooligomerization; GO:0031399 regulation of protein modification process; GO:0043067 regulation of programmed cell death; GO:0050860 negative regulation of T cell receptor signaling pathway; GO:1901700 response to oxygen-containing compound; GO:0022408 negative regulation of cell-cell adhesion; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0032844 regulation of homeostatic process; GO:1905477 positive regulation of protein localization to membrane; GO:0051239 regulation of multicellular organismal process; GO:0060341 regulation of cellular localization; GO:0051259 protein oligomerization; GO:0050866 negative regulation of cell activation; GO:0042493 response to drug; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0071280 cellular response to copper ion; GO:0009889 regulation of biosynthetic process; GO:0031345 negative regulation of cell projection organization; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:0070885 negative regulation of calcineurin-NFAT signaling cascade; GO:0010959 regulation of metal ion transport; GO:0051171 regulation of nitrogen compound metabolic process; GO:0001933 negative regulation of protein phosphorylation; GO:0032880 regulation of protein localization; GO:0050848 regulation of calcium-mediated signaling; GO:0009966 regulation of signal transduction; GO:0048878 chemical homeostasis; GO:1904062 regulation of cation transmembrane transport; GO:0006461 protein complex assembly; GO:0048167 regulation of synaptic plasticity; GO:1902531 regulation of intracellular signal transduction; GO:0006950 response to stress; GO:0050804 modulation of synaptic transmission; GO:1901379 regulation of potassium ion transmembrane transport; GO:0051924 regulation of calcium ion transport; GO:0010033 response to organic substance; GO:0009892 negative regulation of metabolic process; GO:0030155 regulation of cell adhesion; GO:0050849 negative regulation of calcium-mediated signaling; GO:0055070 copper ion homeostasis; GO:0051247 positive regulation of protein metabolic process; GO:1904951 positive regulation of establishment of protein localization; GO:1902951 negative regulation of dendritic spine maintenance; GO:0006873 cellular ion homeostasis; GO:0031325 positive regulation of cellular metabolic process; GO:0071248 cellular response to metal ion; GO:1903827 regulation of cellular protein localization; GO:0090313 regulation of protein targeting to membrane; GO:0045936 negative regulation of phosphate metabolic process; GO:0032689 negative regulation of interferon-gamma production; GO:0050863 regulation of T cell activation; GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity; GO:0009968 negative regulation of signal transduction; GO:0051129 negative regulation of cellular component organization; GO:0023051 regulation of signaling; GO:0051241 negative regulation of multicellular organismal process; GO:0042130 negative regulation of T cell proliferation; GO:0044699 single-organism process; GO:0001818 negative regulation of cytokine production; GO:0051249 regulation of lymphocyte activation; GO:0050858 negative regulation of antigen receptor-mediated signaling pathway; GO:0031400 negative regulation of protein modification process; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0043266 regulation of potassium ion transport; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0022607 cellular component assembly; GO:0006979 response to oxidative stress; GO:0070663 regulation of leukocyte proliferation; GO:0046686 response to cadmium ion; GO:0010035 response to inorganic substance; GO:0002695 negative regulation of leukocyte activation; GO:0051726 regulation of cell cycle; GO:0070887 cellular response to chemical stimulus; GO:0010468 regulation of gene expression; GO:0045937 positive regulation of phosphate metabolic process; GO:0071822 protein complex subunit organization; GO:0050801 ion homeostasis; GO:0031326 regulation of cellular biosynthetic process; GO:0098771 inorganic ion homeostasis; GO:0032703 negative regulation of interleukin-2 production; GO:0019725 cellular homeostasis; GO:0048522 positive regulation of cellular process; GO:0032386 regulation of intracellular transport; GO:1900272 negative regulation of long-term synaptic potentiation; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0010038 response to metal ion; GO:0051050 positive regulation of transport; GO:0010942 positive regulation of cell death; GO:0002683 negative regulation of immune system process; GO:0050865 regulation of cell activation; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0046688 response to copper ion; GO:0050856 regulation of T cell receptor signaling pathway; GO:0007613 memory; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0071241 cellular response to inorganic substance; GO:0044092 negative regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0070271 protein complex biogenesis; GO:0050868 negative regulation of T cell activation; GO:0051222 positive regulation of protein transport; GO:0016043 cellular component organization; GO:0045786 negative regulation of cell cycle; GO:0035690 cellular response to drug; GO:0043069 negative regulation of programmed cell death; GO:0051250 negative regulation of lymphocyte activation; GO:0090316 positive regulation of intracellular protein transport; GO:2000021 regulation of ion homeostasis; GO:0050730 regulation of peptidyl-tyrosine phosphorylation; GO:1903829 positive regulation of cellular protein localization; GO:0060255 regulation of macromolecule metabolic process; GO:0030003 cellular cation homeostasis; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031344 regulation of cell projection organization; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0055082 cellular chemical homeostasis; GO:0070201 regulation of establishment of protein localization; GO:0070884 regulation of calcineurin-NFAT signaling cascade; GO:0042592 homeostatic process; GO:1905475 regulation of protein localization to membrane; GO:0050854 regulation of antigen receptor-mediated signaling pathway; GO:0055080 cation homeostasis; GO:1901216 positive regulation of neuron death; GO:0043066 negative regulation of apoptotic process; GO:0042326 negative regulation of phosphorylation; GO:1903169 regulation of calcium ion transmembrane transport; GO:0050890 cognition; GO:0033157 regulation of intracellular protein transport; GO:0009987 cellular process; GO:1902950 regulation of dendritic spine maintenance; GO:1901214 regulation of neuron death; GO:0032649 regulation of interferon-gamma production; GO:0046007 negative regulation of activated T cell proliferation; GO:0003008 system process; GO:0006355 regulation of transcription, DNA-templated; GO:0007050 cell cycle arrest; GO:0032388 positive regulation of intracellular transport; GO:0051049 regulation of transport; GO:0007616 long-term memory; GO:0090279 regulation of calcium ion import; GO:0001932 regulation of protein phosphorylation; GO:0031401 positive regulation of protein modification process; GO:0032945 negative regulation of mononuclear cell proliferation; GO:0042129 regulation of T cell proliferation; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0032660 regulation of interleukin-17 production; GO:0001934 positive regulation of protein phosphorylation; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0007611 learning or memory; GO:0022407 regulation of cell-cell adhesion; GO:0043933 macromolecular complex subunit organization; GO:0034765 regulation of ion transmembrane transport; GO:0032663 regulation of interleukin-2 production; GO:0051246 regulation of protein metabolic process; GO:0010563 negative regulation of phosphorus metabolic process; GO:0010522 regulation of calcium ion transport into cytosol; GO:0001817 regulation of cytokine production; GO:0051248 negative regulation of protein metabolic process; GO:0006875 cellular metal ion homeostasis; GO:0051128 regulation of cellular component organization; GO:0022402 cell cycle process; GO:0007049 cell cycle; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0030425 dendrite; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0019898 extrinsic component of membrane; GO:0071944 cell periphery; GO:0098857 membrane microdomain; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0032279 asymmetric synapse; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0031965 nuclear membrane; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0098805 whole membrane; GO:0098589 membrane region; GO:0014069 postsynaptic density; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0045121 membrane raft; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0098984 neuron to neuron synapse; GO:0044456 synapse part; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0005635 nuclear envelope; GO:0031225 anchored component of membrane; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0045202 synapse; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0036477 somatodendritic compartment; GO:0098794 postsynapse; GO:0031975 envelope; GO:0009986 cell surface; GO:0005794 Golgi apparatus; GO:0099572 postsynaptic specialization; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0043008 ATP-dependent protein binding; GO:0051087 chaperone binding; GO:0005521 lamin binding; GO:0043167 ion binding; GO:0015631 tubulin binding; GO:0005515 protein binding; GO:0033218 amide binding; GO:0005507 copper ion binding; GO:0004871 signal transducer activity; GO:0001540 beta-amyloid binding; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0042802 identical protein binding; GO:0008092 cytoskeletal protein binding; GO:0046914 transition metal ion binding; GO:0042277 peptide binding; GO:0005488 binding; GO:0008017 microtubule binding; GO:0044325 ion channel binding; GO:0043169 cation binding; GO:0046872 metal ion binding; ","K05634","PRNP; prion protein","hsa04216 Ferroptosis - Homo sapiens (human); hsa05020 Prion diseases - Homo sapiens (human); ","IPR022416; IPR025860; ","\"Prion/Doppel protein, beta-ribbon domain; Major prion protein N-terminal domain; \"\r"]
["P04179","Superoxide dismutase [Mn], mitochondrial OS=Homo sapiens OX=9606 GN=SOD2","SOD2",24.75,76.074,45.5,10,29,10,0.849,0.806,0.833,1.166,1.165,1.15,1.399,2.45e-05,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0006801 superoxide metabolic process; GO:0010941 regulation of cell death; GO:0065008 regulation of biological quality; GO:0043523 regulation of neuron apoptotic process; GO:0044237 cellular metabolic process; GO:0050877 neurological system process; GO:0008285 negative regulation of cell proliferation; GO:0019430 removal of superoxide radicals; GO:0003085 negative regulation of systemic arterial blood pressure; GO:0008152 metabolic process; GO:0065003 macromolecular complex assembly; GO:0098869 cellular oxidant detoxification; GO:0003044 regulation of systemic arterial blood pressure mediated by a chemical signal; GO:0051716 cellular response to stimulus; GO:0001976 neurological system process involved in regulation of systemic arterial blood pressure; GO:0080090 regulation of primary metabolic process; GO:0000302 response to reactive oxygen species; GO:0044763 single-organism cellular process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0035296 regulation of tube diameter; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0003068 regulation of systemic arterial blood pressure by acetylcholine; GO:1903506 regulation of nucleic acid-templated transcription; GO:1902532 negative regulation of intracellular signal transduction; GO:0080135 regulation of cellular response to stress; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:1903202 negative regulation of oxidative stress-induced cell death; GO:0003013 circulatory system process; GO:0060548 negative regulation of cell death; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0097190 apoptotic signaling pathway; GO:0042127 regulation of cell proliferation; GO:0050880 regulation of blood vessel size; GO:0051260 protein homooligomerization; GO:0045776 negative regulation of blood pressure; GO:0043067 regulation of programmed cell death; GO:1901700 response to oxygen-containing compound; GO:0003018 vascular process in circulatory system; GO:0080134 regulation of response to stress; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0051259 protein oligomerization; GO:1990748 cellular detoxification; GO:0023057 negative regulation of signaling; GO:0007571 age-dependent general metabolic decline; GO:0043524 negative regulation of neuron apoptotic process; GO:0010648 negative regulation of cell communication; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0001315 age-dependent response to reactive oxygen species; GO:0035150 regulation of tube size; GO:0009966 regulation of signal transduction; GO:0006461 protein complex assembly; GO:0048878 chemical homeostasis; GO:1901215 negative regulation of neuron death; GO:1902531 regulation of intracellular signal transduction; GO:0006950 response to stress; GO:1900408 negative regulation of cellular response to oxidative stress; GO:0006996 organelle organization; GO:1902882 regulation of response to oxidative stress; GO:0012501 programmed cell death; GO:0000303 response to superoxide; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0097746 regulation of blood vessel diameter; GO:2001141 regulation of RNA biosynthetic process; GO:2001233 regulation of apoptotic signaling pathway; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:2001243 negative regulation of intrinsic apoptotic signaling pathway; GO:0051262 protein tetramerization; GO:0022607 cellular component assembly; GO:0007005 mitochondrion organization; GO:0006915 apoptotic process; GO:0003073 regulation of systemic arterial blood pressure; GO:0006979 response to oxidative stress; GO:0010035 response to inorganic substance; GO:0034599 cellular response to oxidative stress; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0034614 cellular response to reactive oxygen species; GO:0071822 protein complex subunit organization; GO:0031326 regulation of cellular biosynthetic process; GO:0071450 cellular response to oxygen radical; GO:0055114 oxidation-reduction process; GO:0009636 response to toxic substance; GO:0032364 oxygen homeostasis; GO:0003070 regulation of systemic arterial blood pressure by neurotransmitter; GO:0023052 signaling; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:1902883 negative regulation of response to oxidative stress; GO:0007568 aging; GO:0000305 response to oxygen radical; GO:0019222 regulation of metabolic process; GO:0070271 protein complex biogenesis; GO:0098754 detoxification; GO:0003069 acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure; GO:0008217 regulation of blood pressure; GO:0016043 cellular component organization; GO:0043069 negative regulation of programmed cell death; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:1903201 regulation of oxidative stress-induced cell death; GO:0050896 response to stimulus; GO:0042592 homeostatic process; GO:0051289 protein homotetramerization; GO:0072593 reactive oxygen species metabolic process; GO:0043066 negative regulation of apoptotic process; GO:0008015 blood circulation; GO:0009987 cellular process; GO:1901214 regulation of neuron death; GO:0097755 positive regulation of blood vessel diameter; GO:0003008 system process; GO:0006355 regulation of transcription, DNA-templated; GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway; GO:0008637 apoptotic mitochondrial changes; GO:0071451 cellular response to superoxide; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0051252 regulation of RNA metabolic process; GO:0042311 vasodilation; GO:0001836 release of cytochrome c from mitochondria; GO:0043933 macromolecular complex subunit organization; GO:0033483 gas homeostasis; GO:1902176 negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway; GO:1901701 cellular response to oxygen-containing compound; GO:1900407 regulation of cellular response to oxidative stress; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:2001242 regulation of intrinsic apoptotic signaling pathway; GO:0090066 regulation of anatomical structure size; GO:0001306 age-dependent response to oxidative stress; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0044429 mitochondrial part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0004784 superoxide dismutase activity; GO:0042802 identical protein binding; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0016721 oxidoreductase activity, acting on superoxide radicals as acceptor; GO:0005488 binding; GO:0043167 ion binding; GO:0016209 antioxidant activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0030145 manganese ion binding; GO:0016491 oxidoreductase activity; ","K04564","SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]","hsa04068 FoxO signaling pathway - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04213 Longevity regulating pathway - multiple species - Homo sapiens (human); hsa04211 Longevity regulating pathway - Homo sapiens (human); hsa04146 Peroxisome - Homo sapiens (human); ","IPR019831; IPR019832; ","\"Manganese/iron superoxide dismutase, N-terminal; Manganese/iron superoxide dismutase, C-terminal; \"\r"]
["P04181","Ornithine aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=OAT","OAT",48.534,27.54,17.3,6,9,6,1.006,1.016,1.002,1.004,0.936,1.046,0.987,0.716,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:0016043 cellular component organization; GO:0055129 L-proline biosynthetic process; GO:0016053 organic acid biosynthetic process; GO:0007601 visual perception; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:0050877 neurological system process; GO:0009084 glutamine family amino acid biosynthetic process; GO:0051259 protein oligomerization; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0046483 heterocycle metabolic process; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:1901607 alpha-amino acid biosynthetic process; GO:0006560 proline metabolic process; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0009064 glutamine family amino acid metabolic process; GO:0006561 proline biosynthetic process; GO:0008652 cellular amino acid biosynthetic process; GO:0007600 sensory perception; GO:0018130 heterocycle biosynthetic process; GO:0071822 protein complex subunit organization; GO:0003008 system process; GO:0044711 single-organism biosynthetic process; GO:0034214 protein hexamerization; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0050953 sensory perception of light stimulus; GO:1901605 alpha-amino acid metabolic process; GO:0044238 primary metabolic process; GO:0032501 multicellular organismal process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0046394 carboxylic acid biosynthetic process; GO:0044710 single-organism metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0044283 small molecule biosynthetic process; GO:0070271 protein complex biogenesis; GO:0006082 organic acid metabolic process; GO:0043436 oxoacid metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0071840 cellular component organization or biogenesis; GO:1901564 organonitrogen compound metabolic process; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0016769 transferase activity, transferring nitrogenous groups; GO:0004587 ornithine-oxo-acid transaminase activity; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0043168 anion binding; GO:0005515 protein binding; GO:0008483 transaminase activity; GO:0048037 cofactor binding; GO:0016740 transferase activity; GO:0030170 pyridoxal phosphate binding; ","K00819","rocD; ornithine--oxo-acid transaminase [EC:2.6.1.13]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00330 Arginine and proline metabolism - Homo sapiens (human); ","IPR015424; IPR015422; IPR015421; ","\"Pyridoxal phosphate-dependent transferase; Pyridoxal phosphate-dependent transferase, major region, subdomain 2; Pyridoxal phosphate-dependent transferase, major region, subdomain 1; \"\r"]
["P04196","Histidine-rich glycoprotein OS=Homo sapiens OX=9606 GN=HRG","HRG",59.578,52.053,23.8,11,23,11,0.851,0.922,0.895,1.084,1.154,1.174,1.279,0.00188,"extracellular\r","GO:0010941 regulation of cell death; GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0060491 regulation of cell projection assembly; GO:0098542 defense response to other organism; GO:2001026 regulation of endothelial cell chemotaxis; GO:0010594 regulation of endothelial cell migration; GO:0009607 response to biotic stimulus; GO:0008285 negative regulation of cell proliferation; GO:0001558 regulation of cell growth; GO:0042730 fibrinolysis; GO:0009605 response to external stimulus; GO:0010466 negative regulation of peptidase activity; GO:0001525 angiogenesis; GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway; GO:0051894 positive regulation of focal adhesion assembly; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0032102 negative regulation of response to external stimulus; GO:0090303 positive regulation of wound healing; GO:0051493 regulation of cytoskeleton organization; GO:0030194 positive regulation of blood coagulation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0052548 regulation of endopeptidase activity; GO:0001954 positive regulation of cell-matrix adhesion; GO:0042325 regulation of phosphorylation; GO:0009620 response to fungus; GO:0051174 regulation of phosphorus metabolic process; GO:0010632 regulation of epithelial cell migration; GO:0030168 platelet activation; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0090287 regulation of cellular response to growth factor stimulus; GO:1901888 regulation of cell junction assembly; GO:2000146 negative regulation of cell motility; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:1901343 negative regulation of vasculature development; GO:0006935 chemotaxis; GO:1902548 negative regulation of cellular response to vascular endothelial growth factor stimulus; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0010811 positive regulation of cell-substrate adhesion; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0051336 regulation of hydrolase activity; GO:1900048 positive regulation of hemostasis; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0002833 positive regulation of response to biotic stimulus; GO:0045765 regulation of angiogenesis; GO:0042330 taxis; GO:0002682 regulation of immune system process; GO:0050817 coagulation; GO:0043537 negative regulation of blood vessel endothelial cell migration; GO:0043068 positive regulation of programmed cell death; GO:1903036 positive regulation of response to wounding; GO:0072359 circulatory system development; GO:0050794 regulation of cellular process; GO:0001952 regulation of cell-matrix adhesion; GO:0002839 positive regulation of immune response to tumor cell; GO:0044707 single-multicellular organism process; GO:0010951 negative regulation of endopeptidase activity; GO:1902744 negative regulation of lamellipodium organization; GO:0007162 negative regulation of cell adhesion; GO:0042127 regulation of cell proliferation; GO:0032956 regulation of actin cytoskeleton organization; GO:0010543 regulation of platelet activation; GO:0031399 regulation of protein modification process; GO:0043067 regulation of programmed cell death; GO:0030193 regulation of blood coagulation; GO:0002576 platelet degranulation; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0051239 regulation of multicellular organismal process; GO:1900047 negative regulation of hemostasis; GO:0009653 anatomical structure morphogenesis; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:1902578 single-organism localization; GO:0010593 negative regulation of lamellipodium assembly; GO:2000145 regulation of cell motility; GO:0031345 negative regulation of cell projection organization; GO:0007275 multicellular organism development; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0009966 regulation of signal transduction; GO:0050778 positive regulation of immune response; GO:0045861 negative regulation of proteolysis; GO:2000504 positive regulation of blood vessel remodeling; GO:0045785 positive regulation of cell adhesion; GO:0006950 response to stress; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0051917 regulation of fibrinolysis; GO:0071702 organic substance transport; GO:0030334 regulation of cell migration; GO:0072358 cardiovascular system development; GO:0032101 regulation of response to external stimulus; GO:0032970 regulation of actin filament-based process; GO:0030162 regulation of proteolysis; GO:0009892 negative regulation of metabolic process; GO:0030155 regulation of cell adhesion; GO:0030195 negative regulation of blood coagulation; GO:0043535 regulation of blood vessel endothelial cell migration; GO:0045055 regulated exocytosis; GO:0010596 negative regulation of endothelial cell migration; GO:1902547 regulation of cellular response to vascular endothelial growth factor stimulus; GO:0061041 regulation of wound healing; GO:0030336 negative regulation of cell migration; GO:0060312 regulation of blood vessel remodeling; GO:0001775 cell activation; GO:1901678 iron coordination entity transport; GO:0010810 regulation of cell-substrate adhesion; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:0050793 regulation of developmental process; GO:1903034 regulation of response to wounding; GO:0050819 negative regulation of coagulation; GO:0006887 exocytosis; GO:0051093 negative regulation of developmental process; GO:1903391 regulation of adherens junction organization; GO:0002836 positive regulation of response to tumor cell; GO:0009968 negative regulation of signal transduction; GO:0001568 blood vessel development; GO:0010633 negative regulation of epithelial cell migration; GO:0051129 negative regulation of cellular component organization; GO:0050922 negative regulation of chemotaxis; GO:0023051 regulation of signaling; GO:0090109 regulation of cell-substrate junction assembly; GO:0044699 single-organism process; GO:0051241 negative regulation of multicellular organismal process; GO:0034103 regulation of tissue remodeling; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0040013 negative regulation of locomotion; GO:0009611 response to wounding; GO:2001027 negative regulation of endothelial cell chemotaxis; GO:0010646 regulation of cell communication; GO:0015886 heme transport; GO:0032103 positive regulation of response to external stimulus; GO:1900046 regulation of hemostasis; GO:0002834 regulation of response to tumor cell; GO:0048514 blood vessel morphogenesis; GO:2000181 negative regulation of blood vessel morphogenesis; GO:0032502 developmental process; GO:0045926 negative regulation of growth; GO:0010468 regulation of gene expression; GO:0051181 cofactor transport; GO:0010591 regulation of lamellipodium assembly; GO:0001944 vasculature development; GO:0048522 positive regulation of cellular process; GO:1901890 positive regulation of cell junction assembly; GO:0010605 negative regulation of macromolecule metabolic process; GO:1900746 regulation of vascular endothelial growth factor signaling pathway; GO:1903035 negative regulation of response to wounding; GO:0010942 positive regulation of cell death; GO:0030308 negative regulation of cell growth; GO:1903393 positive regulation of adherens junction organization; GO:0033629 negative regulation of cell adhesion mediated by integrin; GO:0016525 negative regulation of angiogenesis; GO:0043254 regulation of protein complex assembly; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0050865 regulation of cell activation; GO:0032940 secretion by cell; GO:0002837 regulation of immune response to tumor cell; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0006952 defense response; GO:0040011 locomotion; GO:0019220 regulation of phosphate metabolic process; GO:0052547 regulation of peptidase activity; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0051271 negative regulation of cellular component movement; GO:0040008 regulation of growth; GO:0002831 regulation of response to biotic stimulus; GO:0050730 regulation of peptidyl-tyrosine phosphorylation; GO:0060255 regulation of macromolecule metabolic process; GO:0051918 negative regulation of fibrinolysis; GO:0051893 regulation of focal adhesion assembly; GO:0043065 positive regulation of apoptotic process; GO:0031344 regulation of cell projection organization; GO:0044087 regulation of cellular component biogenesis; GO:0043207 response to external biotic stimulus; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0007599 hemostasis; GO:0051346 negative regulation of hydrolase activity; GO:1902743 regulation of lamellipodium organization; GO:0090288 negative regulation of cellular response to growth factor stimulus; GO:0009987 cellular process; GO:0050878 regulation of body fluid levels; GO:0034105 positive regulation of tissue remodeling; GO:0033628 regulation of cell adhesion mediated by integrin; GO:1901342 regulation of vasculature development; GO:0001932 regulation of protein phosphorylation; GO:0033043 regulation of organelle organization; GO:0050820 positive regulation of coagulation; GO:0048585 negative regulation of response to stimulus; GO:0050920 regulation of chemotaxis; GO:0048518 positive regulation of biological process; GO:0061045 negative regulation of wound healing; GO:0050832 defense response to fungus; GO:0050818 regulation of coagulation; GO:0042060 wound healing; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0002684 positive regulation of immune system process; GO:0051248 negative regulation of protein metabolic process; GO:0051128 regulation of cellular component organization; GO:0040012 regulation of locomotion; GO:0071705 nitrogen compound transport; GO:0044089 positive regulation of cellular component biogenesis; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0036019 endolysosome; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0072562 blood microparticle; GO:0060205 cytoplasmic vesicle lumen; GO:0005773 vacuole; GO:0031093 platelet alpha granule lumen; GO:0031091 platelet alpha granule; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0019865 immunoglobulin binding; GO:0005102 receptor binding; GO:0061134 peptidase regulator activity; GO:0005515 protein binding; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0008201 heparin binding; GO:0004869 cysteine-type endopeptidase inhibitor activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0020037 heme binding; GO:0005488 binding; GO:0030414 peptidase inhibitor activity; GO:0043169 cation binding; GO:0061135 endopeptidase regulator activity; GO:0043168 anion binding; GO:0005539 glycosaminoglycan binding; GO:0046906 tetrapyrrole binding; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0043394 proteoglycan binding; GO:0043395 heparan sulfate proteoglycan binding; GO:0008270 zinc ion binding; GO:1901681 sulfur compound binding; GO:0004866 endopeptidase inhibitor activity; GO:0004867 serine-type endopeptidase inhibitor activity; GO:0097367 carbohydrate derivative binding; GO:0030234 enzyme regulator activity; GO:0046914 transition metal ion binding; GO:0046872 metal ion binding; GO:0001948 glycoprotein binding; GO:0032403 protein complex binding; ",{"$nulls":3},"IPR000010; ","Cystatin domain; \r"]
["P04216","Thy-1 membrane glycoprotein OS=Homo sapiens OX=9606 GN=THY1","THY1",17.935,14.894,18,2,4,2,0.995,1.148,1.197,1.109,0.775,0.775,0.796,0.143,"extracellular\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0002694 regulation of leukocyte activation; GO:0065008 regulation of biological quality; GO:0060042 retina morphogenesis in camera-type eye; GO:0007166 cell surface receptor signaling pathway; GO:0003407 neural retina development; GO:1904427 positive regulation of calcium ion transmembrane transport; GO:0044237 cellular metabolic process; GO:0042157 lipoprotein metabolic process; GO:0022610 biological adhesion; GO:0008152 metabolic process; GO:0001525 angiogenesis; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0007160 cell-matrix adhesion; GO:0034332 adherens junction organization; GO:0007155 cell adhesion; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0042462 eye photoreceptor cell development; GO:0090596 sensory organ morphogenesis; GO:0007399 nervous system development; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:0048592 eye morphogenesis; GO:0048699 generation of neurons; GO:0046530 photoreceptor cell differentiation; GO:0043269 regulation of ion transport; GO:0044763 single-organism cellular process; GO:0031323 regulation of cellular metabolic process; GO:0043086 negative regulation of catalytic activity; GO:2000146 negative regulation of cell motility; GO:0032501 multicellular organismal process; GO:0048041 focal adhesion assembly; GO:0050776 regulation of immune response; GO:0034762 regulation of transmembrane transport; GO:0050768 negative regulation of neurogenesis; GO:0048513 animal organ development; GO:0051336 regulation of hydrolase activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0045665 negative regulation of neuron differentiation; GO:0044260 cellular macromolecule metabolic process; GO:0098602 single organism cell adhesion; GO:0009887 animal organ morphogenesis; GO:0006497 protein lipidation; GO:0006464 cellular protein modification process; GO:0002682 regulation of immune system process; GO:0010721 negative regulation of cell development; GO:0042670 retinal cone cell differentiation; GO:0010975 regulation of neuron projection development; GO:0043687 post-translational protein modification; GO:0050794 regulation of cellular process; GO:0072359 circulatory system development; GO:0044707 single-multicellular organism process; GO:0016310 phosphorylation; GO:0034764 positive regulation of transmembrane transport; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0031399 regulation of protein modification process; GO:0050860 negative regulation of T cell receptor signaling pathway; GO:0044267 cellular protein metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0032844 regulation of homeostatic process; GO:0051239 regulation of multicellular organismal process; GO:0060341 regulation of cellular localization; GO:0009653 anatomical structure morphogenesis; GO:0001654 eye development; GO:0050867 positive regulation of cell activation; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0051345 positive regulation of hydrolase activity; GO:2000145 regulation of cell motility; GO:0051338 regulation of transferase activity; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:0031345 negative regulation of cell projection organization; GO:0010959 regulation of metal ion transport; GO:0001933 negative regulation of protein phosphorylation; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0050778 positive regulation of immune response; GO:0009966 regulation of signal transduction; GO:0048646 anatomical structure formation involved in morphogenesis; GO:1904062 regulation of cation transmembrane transport; GO:0060219 camera-type eye photoreceptor cell differentiation; GO:0051928 positive regulation of calcium ion transport; GO:0002253 activation of immune response; GO:0010771 negative regulation of cell morphogenesis involved in differentiation; GO:0051282 regulation of sequestering of calcium ion; GO:0045785 positive regulation of cell adhesion; GO:0001754 eye photoreceptor cell differentiation; GO:0051270 regulation of cellular component movement; GO:0043547 positive regulation of GTPase activity; GO:0048731 system development; GO:0051960 regulation of nervous system development; GO:0060284 regulation of cell development; GO:0051924 regulation of calcium ion transport; GO:0002376 immune system process; GO:0030334 regulation of cell migration; GO:0010977 negative regulation of neuron projection development; GO:0072358 cardiovascular system development; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1903039 positive regulation of leukocyte cell-cell adhesion; GO:1901576 organic substance biosynthetic process; GO:0030155 regulation of cell adhesion; GO:0050770 regulation of axonogenesis; GO:0030182 neuron differentiation; GO:0002696 positive regulation of leukocyte activation; GO:0043270 positive regulation of ion transport; GO:0030336 negative regulation of cell migration; GO:1904064 positive regulation of cation transmembrane transport; GO:0006793 phosphorus metabolic process; GO:0050870 positive regulation of T cell activation; GO:0006996 organelle organization; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:0007423 sensory organ development; GO:0048584 positive regulation of response to stimulus; GO:0043412 macromolecule modification; GO:0050793 regulation of developmental process; GO:0045936 negative regulation of phosphate metabolic process; GO:0050863 regulation of T cell activation; GO:0051093 negative regulation of developmental process; GO:0009968 negative regulation of signal transduction; GO:0001568 blood vessel development; GO:0048666 neuron development; GO:0023051 regulation of signaling; GO:0048869 cellular developmental process; GO:0051129 negative regulation of cellular component organization; GO:0045216 cell-cell junction organization; GO:0044699 single-organism process; GO:0051241 negative regulation of multicellular organismal process; GO:0022008 neurogenesis; GO:0009058 biosynthetic process; GO:0051249 regulation of lymphocyte activation; GO:0050858 negative regulation of antigen receptor-mediated signaling pathway; GO:0031400 negative regulation of protein modification process; GO:0006796 phosphate-containing compound metabolic process; GO:0040013 negative regulation of locomotion; GO:0007165 signal transduction; GO:0016337 single organismal cell-cell adhesion; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0033673 negative regulation of kinase activity; GO:0032846 positive regulation of homeostatic process; GO:0046777 protein autophosphorylation; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0007045 cell-substrate adherens junction assembly; GO:0042461 photoreceptor cell development; GO:0048514 blood vessel morphogenesis; GO:0045596 negative regulation of cell differentiation; GO:0050771 negative regulation of axonogenesis; GO:0042158 lipoprotein biosynthetic process; GO:0050851 antigen receptor-mediated signaling pathway; GO:0032502 developmental process; GO:0007044 cell-substrate junction assembly; GO:0051279 regulation of release of sequestered calcium ion into cytosol; GO:0098609 cell-cell adhesion; GO:0090280 positive regulation of calcium ion import; GO:0048522 positive regulation of cellular process; GO:0001944 vasculature development; GO:0051251 positive regulation of lymphocyte activation; GO:0051348 negative regulation of transferase activity; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051050 positive regulation of transport; GO:0002683 negative regulation of immune system process; GO:0032268 regulation of cellular protein metabolic process; GO:0050865 regulation of cell activation; GO:0050789 regulation of biological process; GO:0034767 positive regulation of ion transmembrane transport; GO:0045664 regulation of neuron differentiation; GO:0050856 regulation of T cell receptor signaling pathway; GO:0019222 regulation of metabolic process; GO:0006469 negative regulation of protein kinase activity; GO:0065009 regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0044092 negative regulation of molecular function; GO:0034333 adherens junction assembly; GO:0019220 regulation of phosphate metabolic process; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0046549 retinal cone cell development; GO:0043549 regulation of kinase activity; GO:0051271 negative regulation of cellular component movement; GO:2000026 regulation of multicellular organismal development; GO:0045859 regulation of protein kinase activity; GO:0016043 cellular component organization; GO:0034329 cell junction assembly; GO:0043010 camera-type eye development; GO:2000021 regulation of ion homeostasis; GO:0060255 regulation of macromolecule metabolic process; GO:0031344 regulation of cell projection organization; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0071704 organic substance metabolic process; GO:0050854 regulation of antigen receptor-mediated signaling pathway; GO:0030154 cell differentiation; GO:0006468 protein phosphorylation; GO:0051961 negative regulation of nervous system development; GO:0042326 negative regulation of phosphorylation; GO:1903169 regulation of calcium ion transmembrane transport; GO:0002757 immune response-activating signal transduction; GO:0010524 positive regulation of calcium ion transport into cytosol; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0060041 retina development in camera-type eye; GO:0006501 C-terminal protein lipidation; GO:0022409 positive regulation of cell-cell adhesion; GO:0051049 regulation of transport; GO:0090279 regulation of calcium ion import; GO:0048593 camera-type eye morphogenesis; GO:0001932 regulation of protein phosphorylation; GO:0048585 negative regulation of response to stimulus; GO:0018410 C-terminal protein amino acid modification; GO:0048518 positive regulation of biological process; GO:0022407 regulation of cell-cell adhesion; GO:0044249 cellular biosynthetic process; GO:0043085 positive regulation of catalytic activity; GO:0050852 T cell receptor signaling pathway; GO:0034765 regulation of ion transmembrane transport; GO:0034645 cellular macromolecule biosynthetic process; GO:0034330 cell junction organization; GO:0051281 positive regulation of release of sequestered calcium ion into cytosol; GO:0031589 cell-substrate adhesion; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0010563 negative regulation of phosphorus metabolic process; GO:0002684 positive regulation of immune system process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0010522 regulation of calcium ion transport into cytosol; GO:0051248 negative regulation of protein metabolic process; GO:0051128 regulation of cellular component organization; GO:0040012 regulation of locomotion; GO:0022604 regulation of cell morphogenesis; GO:0065007 biological regulation; GO:0050767 regulation of neurogenesis; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0030425 dendrite; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0009897 external side of plasma membrane; GO:0016324 apical plasma membrane; GO:0098857 membrane microdomain; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0030426 growth cone; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0098590 plasma membrane region; GO:0043209 myelin sheath; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0098805 whole membrane; GO:0098589 membrane region; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0030055 cell-substrate junction; GO:0045121 membrane raft; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0045177 apical part of cell; GO:0031233 intrinsic component of external side of plasma membrane; GO:0005924 cell-substrate adherens junction; GO:0098552 side of membrane; GO:0043229 intracellular organelle; GO:0031226 intrinsic component of plasma membrane; GO:0042995 cell projection; GO:0031225 anchored component of membrane; GO:0070161 anchoring junction; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0030427 site of polarized growth; GO:0044463 cell projection part; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0046658 anchored component of plasma membrane; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031362 anchored component of external side of plasma membrane; GO:0036477 somatodendritic compartment; GO:0044459 plasma membrane part; GO:0009986 cell surface; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005102 receptor binding; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0030695 GTPase regulator activity; GO:0043167 ion binding; GO:0044877 macromolecular complex binding; GO:0019901 protein kinase binding; GO:0005515 protein binding; GO:0005178 integrin binding; GO:0098772 molecular function regulator; GO:0019900 kinase binding; GO:0050839 cell adhesion molecule binding; GO:0097367 carbohydrate derivative binding; GO:0051861 glycolipid binding; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0034235 GPI anchor binding; GO:0035091 phosphatidylinositol binding; GO:0005543 phospholipid binding; GO:0008289 lipid binding; GO:0043168 anion binding; GO:0008047 enzyme activator activity; GO:0019899 enzyme binding; GO:0005096 GTPase activator activity; GO:0032403 protein complex binding; ","K06514","THY1; Thy-1 cell surface antigen","hsa04670 Leukocyte transendothelial migration - Homo sapiens (human); ","IPR007110; IPR013783; IPR013106; IPR013151; ","Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin V-set domain; Immunoglobulin; \r"]
["P04217","Alpha-1B-glycoprotein OS=Homo sapiens OX=9606 GN=A1BG","A1BG",54.253,71.848,26.9,9,24,9,0.926,0.973,0.961,1.068,1.053,1.015,1.097,0.0123,"extracellular\r","GO:0045321 leukocyte activation; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0044699 single-organism process; GO:0002576 platelet degranulation; GO:0050896 response to stimulus; GO:0051234 establishment of localization; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0002274 myeloid leukocyte activation; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0002443 leukocyte mediated immunity; GO:0016192 vesicle-mediated transport; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0002376 immune system process; GO:0043312 neutrophil degranulation; GO:0002263 cell activation involved in immune response; GO:0002444 myeloid leukocyte mediated immunity; GO:0006810 transport; GO:0002366 leukocyte activation involved in immune response; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:0032940 secretion by cell; GO:0001775 cell activation; GO:0043299 leukocyte degranulation; GO:0006955 immune response; GO:0051179 localization; GO:0006887 exocytosis; ","GO:0034774 secretory granule lumen; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0043226 organelle; GO:0072562 blood microparticle; GO:0060205 cytoplasmic vesicle lumen; GO:0031093 platelet alpha granule lumen; GO:0031091 platelet alpha granule; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR003598; IPR007110; IPR013783; IPR003599; ","Immunoglobulin subtype 2; Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin subtype; \r"]
["P04233","HLA class II histocompatibility antigen gamma chain OS=Homo sapiens OX=9606 GN=CD74","CD74",33.515,31.661,16.2,4,5,4,0.904,0.936,0.905,1.055,1.169,1.114,1.216,0.00358,"nucleus\r",{"$cut":{"chars":18045,"head":"GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0002694 regulation of leukocyte activation; GO:0010941 regulation of cell death; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0008610 lipid biosynthetic process; GO:0030888 regulation of B cell proliferation; GO:0042110 T cell activation; GO:0048145 regulation of fibroblast proliferation; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0008152 metabolic process; GO:0032946 positive regulation of mononuclear cell proliferation; GO:0048146 positive regulation of fibroblast proliferation; GO:1902165 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; GO:0065003 macromolecular complex assembly; GO:0044093 positive regulation of molecular function; GO:0045621 positive regulation of lymphocyte differentiation; GO:0090022 regulation of neutrophil chemotaxis; GO:0043383 negative T cell selection; GO:0051051 negative regulation of transport; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0046457 prostanoid biosynthetic process; GO:1903038 negative regulation of leukocyte cell-cell adhesion; GO:0050864 regulation of B cell activation; GO:0060760 positive regulation of response to cytokine stimulus; GO:0002905 regulation of mature B cell apoptotic process; GO:0044763 single-organism cellular process; GO:0070229 negative regulation of lymphocyte apoptotic process; GO:0002520 immune system development; GO:0048870 cell motility; GO:0050776 regulation of immune response; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0006810 transport; GO:0019884 antigen processing and presentation of exogenous antigen; GO:1902532 negative regulation of intracellular signal transduction; GO:0080135 regulation of cellular response to stress; GO:1902253 regulation of intrinsic apoptotic signaling pathway by p53 class mediator; GO:0048583 regulation of response to stimulus; GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production; GO:0060548 negative regulation of cell death; GO:0002687 positive regulation of leukocyte migration; GO:0043436 oxoacid metabolic process; GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator; GO:0033559 unsaturated fatty acid metabolic process; GO:0044707 single-multicellular organism process; GO:0002718 regulation of cytokine production involved in immune response; GO:0045580 regulation of T cell differentiation; GO:0001819 positive regulation of cytokine production; GO:0022408 negative regulation of cell-cell adhesion; GO:0048519 negative regulation of biological process; GO:0001516 prostaglandin biosynthetic process; GO:1903706 regulation of hemopoiesis; GO:0019724 B cell mediated immunity; GO:0002579 positive regulation of antigen processing and presentation; GO:0030098 lymphocyte differentiation; GO:0050867 positive regulation of cell activation; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:2000145 regulation of cell motility; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:0034613 cellular protein localization; GO:0002449 lymphocyte mediated immunity; GO:0030217 T cell differentiation; GO:0050778 positive regulation of immune response; GO:0002604 regulation of dendritic cell antigen processing and presentation; GO:1901797 negative regulation of signal transduction by p53 class mediator; GO:0045785 positive regulation of cell adhesion; GO:0051084 'de novo' posttranslational protein folding; GO:0044711 single-organism biosynthetic process; GO:0006950 response to stress; GO:0051270 regulation of cellular component movement; GO:0001961 positive regulation of cytokine-mediated signaling pathway; GO:0032101 regulation of response to external stimulus; GO:0008283 cell proliferation; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0060907 positive regulation of macrophage cytok"}},"GO:0016020 membrane; GO:0044421 extracellular region part; GO:0009897 external side of plasma membrane; GO:0045334 clathrin-coated endocytic vesicle; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0032588 trans-Golgi network membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0005765 lysosomal membrane; GO:0070062 extracellular exosome; GO:0042613 MHC class II protein complex; GO:0030136 clathrin-coated vesicle; GO:0005622 intracellular; GO:0005764 lysosome; GO:0098791 Golgi subcompartment; GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane; GO:0043227 membrane-bounded organelle; GO:0005771 multivesicular body; GO:0005789 endoplasmic reticulum membrane; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0098552 side of membrane; GO:0005770 late endosome; GO:0030666 endocytic vesicle membrane; GO:0098797 plasma membrane protein complex; GO:0043235 receptor complex; GO:0012506 vesicle membrane; GO:0030135 coated vesicle; GO:0043202 lysosomal lumen; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0098553 lumenal side of endoplasmic reticulum membrane; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0035692 macrophage migration inhibitory factor receptor complex; GO:0035693 NOS2-CD74 complex; GO:0030133 transport vesicle; GO:0030176 integral component of endoplasmic reticulum membrane; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0030658 transport vesicle membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0042611 MHC protein complex; GO:0030669 clathrin-coated endocytic vesicle membrane; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0030662 coated vesicle membrane; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0044464 cell part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0031227 intrinsic component of endoplasmic reticulum membrane; GO:0005768 endosome; GO:0030139 endocytic vesicle; GO:0012507 ER to Golgi transport vesicle membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0030134 ER to Golgi transport vesicle; GO:0012505 endomembrane system; GO:0030665 clathrin-coated vesicle membrane; GO:0016021 integral component of membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0044432 endoplasmic reticulum part; GO:0005802 trans-Golgi network; GO:0005774 vacuolar membrane; GO:0009986 cell surface; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; GO:0031984 organelle subcompartment; ","GO:0038023 signaling receptor activity; GO:0035718 macrophage migration inhibitory factor binding; GO:0004896 cytokine receptor activity; GO:0005102 receptor binding; GO:0044877 macromolecular complex binding; GO:0042289 MHC class II protein binding; GO:0050998 nitric-oxide synthase binding; GO:0005515 protein binding; GO:0033218 amide binding; GO:0004888 transmembrane signaling receptor activity; GO:0004871 signal transducer activity; GO:0003823 antigen binding; GO:0044183 protein binding involved in protein folding; GO:0001540 beta-amyloid binding; GO:0019955 cytokine binding; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0042802 identical protein binding; GO:0042277 peptide binding; GO:0042658 MHC class II protein binding, via antigen binding groove; GO:0023023 MHC protein complex binding; GO:0005488 binding; GO:0023026 MHC class II protein complex binding; GO:0042287 MHC protein binding; GO:0019899 enzyme binding; GO:0032403 protein complex binding; GO:0099600 transmembrane receptor activity; ","K06505","CD74; CD74 antigen","hsa05152 Tuberculosis - Homo sapiens (human); hsa04612 Antigen processing and presentation - Homo sapiens (human); hsa05168 Herpes simplex infection - Homo sapiens (human); ","IPR011988; IPR000716; IPR015386; ","\"MHC class II-associated invariant chain, trimerisation; Thyroglobulin type-1; MHC class II-associated invariant chain/CLIP, MHC II-interacting; \"\r"]
["P04264","Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1","KRT1",66.038,233.97,35.2,28,5,1,1.089,1.064,1.037,0.862,0.935,0.995,0.875,0.0372,"nucleus\r","GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0031424 keratinization; GO:0048869 cellular developmental process; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0031347 regulation of defense response; GO:0048871 multicellular organismal homeostasis; GO:0051234 establishment of localization; GO:0042730 fibrinolysis; GO:0006956 complement activation; GO:0009913 epidermal cell differentiation; GO:0008152 metabolic process; GO:0032102 negative regulation of response to external stimulus; GO:0006979 response to oxidative stress; GO:1900046 regulation of hemostasis; GO:0008544 epidermis development; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0002443 leukocyte mediated immunity; GO:0043588 skin development; GO:0009888 tissue development; GO:0030216 keratinocyte differentiation; GO:0002446 neutrophil mediated immunity; GO:0070268 cornification; GO:0044763 single-organism cellular process; GO:0032501 multicellular organismal process; GO:1903035 negative regulation of response to wounding; GO:0002444 myeloid leukocyte mediated immunity; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0030104 water homeostasis; GO:0001895 retina homeostasis; GO:0032940 secretion by cell; GO:0001894 tissue homeostasis; GO:0048583 regulation of response to stimulus; GO:0045765 regulation of angiogenesis; GO:0002682 regulation of immune system process; GO:0006952 defense response; GO:0043299 leukocyte degranulation; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0030855 epithelial cell differentiation; GO:0044707 single-multicellular organism process; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0050728 negative regulation of inflammatory response; GO:0030193 regulation of blood coagulation; GO:0006959 humoral immune response; GO:0048519 negative regulation of biological process; GO:0080134 regulation of response to stress; GO:0050896 response to stimulus; GO:0060249 anatomical structure homeostasis; GO:0045087 innate immune response; GO:0051239 regulation of multicellular organismal process; GO:0071704 organic substance metabolic process; GO:1900047 negative regulation of hemostasis; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:0001867 complement activation, lectin pathway; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0061436 establishment of skin barrier; GO:0007275 multicellular organism development; GO:0036230 granulocyte activation; GO:0050778 positive regulation of immune response; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0031348 negative regulation of defense response; GO:0002253 activation of immune response; GO:0050878 regulation of body fluid levels; GO:0006950 response to stress; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:1901342 regulation of vasculature development; GO:0072376 protein activation cascade; GO:0032101 regulation of response to external stimulus; GO:0002376 immune system process; GO:0048585 negative regulation of response to stimulus; GO:0044238 primary metabolic process; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0061045 negative regulation of wound healing; GO:0002263 cell activation involved in immune response; GO:0050818 regulation of coagulation; GO:0002366 leukocyte activation involved in immune response; GO:0030195 negative regulation of blood coagulation; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0061041 regulation of wound healing; GO:0008219 cell death; GO:0050891 multicellular organismal water homeostasis; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0002684 positive regulation of immune system process; GO:0050727 regulation of inflammatory response; GO:0001775 cell activation; GO:0033561 regulation of water loss via skin; GO:0012501 programmed cell death; GO:0048584 positive regulation of response to stimulus; GO:0006955 immune response; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:1903034 regulation of response to wounding; GO:0050819 negative regulation of coagulation; GO:0006887 exocytosis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005856 cytoskeleton; GO:0031974 membrane-enclosed lumen; GO:0101002 ficolin-1-rich granule; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0045095 keratin filament; GO:0005886 plasma membrane; GO:0099081 supramolecular polymer; GO:0043231 intracellular membrane-bounded organelle; GO:0031012 extracellular matrix; GO:0043226 organelle; GO:0005634 nucleus; GO:0072562 blood microparticle; GO:0045111 intermediate filament cytoskeleton; GO:0005882 intermediate filament; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0030246 carbohydrate binding; GO:0060089 molecular transducer activity; GO:0005515 protein binding; GO:0004872 receptor activity; GO:0005198 structural molecule activity; GO:0005488 binding; ","K07605",null,null,"IPR032449; IPR032444; ","\"Keratin type II cytoskeletal 1, tail; Keratin type II head; \"\r"]
["P04271","Protein S100-B OS=Homo sapiens OX=9606 GN=S100B","S100B",10.713,30.431,32.6,2,3,2,1.069,1.169,1.271,0.853,0.768,0.896,0.717,0.00798,"cytoplasm\r","GO:0051093 negative regulation of developmental process; GO:0065008 regulation of biological quality; GO:0010941 regulation of cell death; GO:0048869 cellular developmental process; GO:0048666 neuron development; GO:0023051 regulation of signaling; GO:2001015 negative regulation of skeletal muscle cell differentiation; GO:0048634 regulation of muscle organ development; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0032989 cellular component morphogenesis; GO:0022008 neurogenesis; GO:1901862 negative regulation of muscle tissue development; GO:0051241 negative regulation of multicellular organismal process; GO:2001014 regulation of skeletal muscle cell differentiation; GO:0050877 neurological system process; GO:0007610 behavior; GO:0050806 positive regulation of synaptic transmission; GO:0010646 regulation of cell communication; GO:0032990 cell part morphogenesis; GO:0045843 negative regulation of striated muscle tissue development; GO:0008360 regulation of cell shape; GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling; GO:0048545 response to steroid hormone; GO:0009719 response to endogenous stimulus; GO:0048858 cell projection morphogenesis; GO:0051597 response to methylmercury; GO:0045596 negative regulation of cell differentiation; GO:0070887 cellular response to chemical stimulus; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0048812 neuron projection morphogenesis; GO:0048168 regulation of neuronal synaptic plasticity; GO:0060291 long-term synaptic potentiation; GO:0032501 multicellular organismal process; GO:0051384 response to glucocorticoid; GO:0010942 positive regulation of cell death; GO:0000902 cell morphogenesis; GO:0048635 negative regulation of muscle organ development; GO:0016202 regulation of striated muscle tissue development; GO:0042063 gliogenesis; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0030030 cell projection organization; GO:0007417 central nervous system development; GO:0048583 regulation of response to stimulus; GO:0048708 astrocyte differentiation; GO:0007613 memory; GO:0006952 defense response; GO:0048856 anatomical structure development; GO:0044708 single-organism behavior; GO:0043068 positive regulation of programmed cell death; GO:2000026 regulation of multicellular organismal development; GO:0048641 regulation of skeletal muscle tissue development; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0042127 regulation of cell proliferation; GO:0009628 response to abiotic stimulus; GO:0043067 regulation of programmed cell death; GO:0043065 positive regulation of apoptotic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:0045087 innate immune response; GO:0048468 cell development; GO:0048642 negative regulation of skeletal muscle tissue development; GO:0000904 cell morphogenesis involved in differentiation; GO:0033993 response to lipid; GO:0009653 anatomical structure morphogenesis; GO:0030154 cell differentiation; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0023056 positive regulation of signaling; GO:0001666 response to hypoxia; GO:0007409 axonogenesis; GO:0031960 response to corticosteroid; GO:0050890 cognition; GO:0070482 response to oxygen levels; GO:0010647 positive regulation of cell communication; GO:0007275 multicellular organism development; GO:0071453 cellular response to oxygen levels; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:0048167 regulation of synaptic plasticity; GO:0045595 regulation of cell differentiation; GO:0071456 cellular response to hypoxia; GO:1902531 regulation of intracellular signal transduction; GO:0003008 system process; GO:0006950 response to stress; GO:0048731 system development; GO:1901861 regulation of muscle tissue development; GO:0050804 modulation of synaptic transmission; GO:0008283 cell proliferation; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0031175 neuron projection development; GO:0048518 positive regulation of biological process; GO:0007611 learning or memory; GO:0010001 glial cell differentiation; GO:0030182 neuron differentiation; GO:0061564 axon development; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling; GO:0009967 positive regulation of signal transduction; GO:0036293 response to decreased oxygen levels; GO:0051128 regulation of cellular component organization; GO:0048584 positive regulation of response to stimulus; GO:0009725 response to hormone; GO:0006955 immune response; GO:0050793 regulation of developmental process; GO:0022604 regulation of cell morphogenesis; GO:0036294 cellular response to decreased oxygen levels; GO:0042981 regulation of apoptotic process; GO:0008284 positive regulation of cell proliferation; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0031252 cell leading edge; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0043025 neuronal cell body; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0036477 somatodendritic compartment; GO:0005622 intracellular; GO:0044464 cell part; GO:0048471 perinuclear region of cytoplasm; GO:0001726 ruffle; GO:0044297 cell body; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0044444 cytoplasmic part; ","GO:0005102 receptor binding; GO:0046983 protein dimerization activity; GO:0043167 ion binding; GO:0048156 tau protein binding; GO:0005515 protein binding; GO:0008270 zinc ion binding; GO:0048306 calcium-dependent protein binding; GO:0050786 RAGE receptor binding; GO:0042802 identical protein binding; GO:0008092 cytoskeletal protein binding; GO:0046914 transition metal ion binding; GO:0005488 binding; GO:0042803 protein homodimerization activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0044548 S100 protein binding; GO:0005509 calcium ion binding; ",{"$nulls":3},"IPR002048; IPR011992; IPR013787; ","\"EF-hand domain; EF-hand domain pair; S100/CaBP-9k-type, calcium binding, subdomain; \"\r"]
["P04275","von Willebrand factor OS=Homo sapiens OX=9606 GN=VWF","VWF",309.26,171.14,18.2,44,51,44,1.045,1.04,1.057,0.955,0.952,0.957,0.912,5.59e-05,"extracellular\r","GO:0044085 cellular component biogenesis; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0051260 protein homooligomerization; GO:0002576 platelet degranulation; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0007599 hemostasis; GO:0051234 establishment of localization; GO:0051259 protein oligomerization; GO:0071704 organic substance metabolic process; GO:0009611 response to wounding; GO:0022610 biological adhesion; GO:0008152 metabolic process; GO:1902578 single-organism localization; GO:0022607 cellular component assembly; GO:0043062 extracellular structure organization; GO:0065003 macromolecular complex assembly; GO:0007155 cell adhesion; GO:0030198 extracellular matrix organization; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0050878 regulation of body fluid levels; GO:0071822 protein complex subunit organization; GO:0006950 response to stress; GO:0007597 blood coagulation, intrinsic pathway; GO:0030168 platelet activation; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0072376 protein activation cascade; GO:0044238 primary metabolic process; GO:0032501 multicellular organismal process; GO:0072378 blood coagulation, fibrin clot formation; GO:0043933 macromolecular complex subunit organization; GO:0006810 transport; GO:0045055 regulated exocytosis; GO:0042060 wound healing; GO:0031589 cell-substrate adhesion; GO:0032940 secretion by cell; GO:0001775 cell activation; GO:0050817 coagulation; GO:0051179 localization; GO:0070271 protein complex biogenesis; GO:0006887 exocytosis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0030136 clathrin-coated vesicle; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0033093 Weibel-Palade body; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0030135 coated vesicle; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031012 extracellular matrix; GO:0060205 cytoplasmic vesicle lumen; GO:0005578 proteinaceous extracellular matrix; GO:0031093 platelet alpha granule lumen; GO:0031091 platelet alpha granule; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0047485 protein N-terminus binding; GO:0019865 immunoglobulin binding; GO:0005102 receptor binding; GO:0051087 chaperone binding; GO:0046983 protein dimerization activity; GO:0044877 macromolecular complex binding; GO:0005515 protein binding; GO:0005178 integrin binding; GO:0002020 protease binding; GO:0050839 cell adhesion molecule binding; GO:0097367 carbohydrate derivative binding; GO:0042802 identical protein binding; GO:0005488 binding; GO:0042803 protein homodimerization activity; GO:0005518 collagen binding; GO:0001948 glycoprotein binding; GO:0019899 enzyme binding; GO:0032403 protein complex binding; ","K03900","VWF; von Willebrand factor","hsa04611 Platelet activation - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa04610 Complement and coagulation cascades - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa04512 ECM-receptor interaction - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); ","IPR032361; IPR014853; IPR002919; IPR001007; IPR001846; IPR006207; IPR002035; ","\"von Willebrand factor, VWA N-terminal domain; Uncharacterised domain, cysteine-rich; Trypsin Inhibitor-like, cysteine rich domain; VWFC domain; von Willebrand factor, type D domain; Cystine knot, C-terminal; von Willebrand factor, type A; \"\r"]
["P04350","Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A","TUBB4A",49.585,71.866,60.6,18,93,2,1.107,1.089,1.108,0.92,0.868,0.864,0.803,0.000463,"cyto_nucl\r","GO:0044085 cellular component biogenesis; GO:0000278 mitotic cell cycle; GO:0016043 cellular component organization; GO:0044763 single-organism cellular process; GO:0060271 cilium assembly; GO:0044699 single-organism process; GO:0097711 ciliary basal body docking; GO:1903047 mitotic cell cycle process; GO:0007017 microtubule-based process; GO:0022406 membrane docking; GO:0044782 cilium organization; GO:0030031 cell projection assembly; GO:1902589 single-organism organelle organization; GO:0070925 organelle assembly; GO:0022607 cellular component assembly; GO:0030030 cell projection organization; GO:0006996 organelle organization; GO:0044770 cell cycle phase transition; GO:0022402 cell cycle process; GO:0044839 cell cycle G2/M phase transition; GO:0007010 cytoskeleton organization; GO:0000086 G2/M transition of mitotic cell cycle; GO:0009987 cellular process; GO:0007049 cell cycle; GO:0044772 mitotic cell cycle phase transition; GO:0071840 cellular component organization or biogenesis; ","GO:0044421 extracellular region part; GO:0005874 microtubule; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0043025 neuronal cell body; GO:0044424 intracellular part; GO:0099512 supramolecular fiber; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005856 cytoskeleton; GO:0015630 microtubule cytoskeleton; GO:0043209 myelin sheath; GO:0044304 main axon; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0005929 cilium; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0099513 polymeric cytoskeletal fiber; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0033269 internode region of axon; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0005576 extracellular region; GO:0033267 axon part; GO:0099081 supramolecular polymer; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0030424 axon; GO:0005634 nucleus; GO:0036477 somatodendritic compartment; GO:0044297 cell body; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0005200 structural constituent of cytoskeleton; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0003924 GTPase activity; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019001 guanyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005525 GTP binding; GO:0005198 structural molecule activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0036094 small molecule binding; ","K07375","TUBB; tubulin beta","hsa04540 Gap junction - Homo sapiens (human); hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); ","IPR003008; IPR023123; IPR018316; IPR008280; ","\"Tubulin/FtsZ, GTPase domain; Tubulin, C-terminal; Tubulin/FtsZ, 2-layer sandwich domain; Tubulin/FtsZ, C-terminal; \"\r"]
["P04406","Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH","GAPDH",36.053,323.31,61.2,18,105,18,0.999,0.963,0.978,1.008,1.017,1.026,1.038,0.0346,"cytoplasm\r","GO:0065008 regulation of biological quality; GO:0009116 nucleoside metabolic process; GO:0006165 nucleoside diphosphate phosphorylation; GO:0019362 pyridine nucleotide metabolic process; GO:0070997 neuron death; GO:0006096 glycolytic process; GO:0010608 posttranscriptional regulation of gene expression; GO:0009185 ribonucleoside diphosphate metabolic process; GO:0071345 cellular response to cytokine stimulus; GO:0044237 cellular metabolic process; GO:0006006 glucose metabolic process; GO:0008152 metabolic process; GO:0006094 gluconeogenesis; GO:0006091 generation of precursor metabolites and energy; GO:0035606 peptidyl-cysteine S-trans-nitrosylation; GO:0032787 monocarboxylic acid metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0051716 cellular response to stimulus; GO:0009179 purine ribonucleoside diphosphate metabolic process; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0061620 glycolytic process through glucose-6-phosphate; GO:0034249 negative regulation of cellular amide metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0006732 coenzyme metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0005975 carbohydrate metabolic process; GO:0010506 regulation of autophagy; GO:0061718 glucose catabolic process to pyruvate; GO:0016241 regulation of macroautophagy; GO:0000226 microtubule cytoskeleton organization; GO:1901575 organic substance catabolic process; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0018198 peptidyl-cysteine modification; GO:0019674 NAD metabolic process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0009126 purine nucleoside monophosphate metabolic process; GO:0043436 oxoacid metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016310 phosphorylation; GO:0046496 nicotinamide nucleotide metabolic process; GO:0009259 ribonucleotide metabolic process; GO:0044267 cellular protein metabolic process; GO:0046364 monosaccharide biosynthetic process; GO:0017148 negative regulation of translation; GO:0006735 NADH regeneration; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0018119 peptidyl-cysteine S-nitrosylation; GO:0051171 regulation of nitrogen compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0007010 cytoskeleton organization; GO:0017014 protein nitrosylation; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0009119 ribonucleoside metabolic process; GO:0044711 single-organism biosynthetic process; GO:0006950 response to stress; GO:0002376 immune system process; GO:0009141 nucleoside triphosphate metabolic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0007017 microtubule-based process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0006163 purine nucleotide metabolic process; GO:0034248 regulation of cellular amide metabolic process; GO:0009890 negative regulation of biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0044283 small molecule biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0031647 regulation of protein stability; GO:0012501 programmed cell death; GO:0019320 hexose catabolic process; GO:0043412 macromolecule modification; GO:0006955 immune response; GO:0050821 protein stabilization; GO:0019318 hexose metabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0006757 ATP generation from ADP; GO:0046365 monosaccharide catabolic process; GO:0042278 purine nucleoside metabolic process; GO:0046031 ADP metabolic process; GO:0019319 hexose biosynthetic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0071346 cellular response to interferon-gamma; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0046939 nucleotide phosphorylation; GO:0009135 purine nucleoside diphosphate metabolic process; GO:0072524 pyridine-containing compound metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0061615 glycolytic process through fructose-6-phosphate; GO:0006753 nucleoside phosphate metabolic process; GO:0006915 apoptotic process; GO:0070887 cellular response to chemical stimulus; GO:0010468 regulation of gene expression; GO:0051402 neuron apoptotic process; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0034097 response to cytokine; GO:0031326 regulation of cellular biosynthetic process; GO:0055114 oxidation-reduction process; GO:1901360 organic cyclic compound metabolic process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051186 cofactor metabolic process; GO:0016052 carbohydrate catabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0019222 regulation of metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0006952 defense response; GO:0036211 protein modification process; GO:0006082 organic acid metabolic process; GO:0016043 cellular component organization; GO:0016051 carbohydrate biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0006734 NADH metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0045087 innate immune response; GO:0071704 organic substance metabolic process; GO:0061621 canonical glycolysis; GO:0006090 pyruvate metabolic process; GO:0005996 monosaccharide metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0009132 nucleoside diphosphate metabolic process; GO:0046034 ATP metabolic process; GO:0044724 single-organism carbohydrate catabolic process; GO:0010629 negative regulation of gene expression; GO:0044712 single-organism catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044282 small molecule catabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0034341 response to interferon-gamma; GO:0018193 peptidyl-amino acid modification; GO:0046128 purine ribonucleoside metabolic process; GO:0006007 glucose catabolic process; GO:0008219 cell death; GO:0051246 regulation of protein metabolic process; GO:0006417 regulation of translation; GO:0019752 carboxylic acid metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0097452 GAIT complex; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0031965 nuclear membrane; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0005811 lipid particle; GO:0043227 membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005635 nuclear envelope; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0031012 extracellular matrix; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0031975 envelope; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0016769 transferase activity, transferring nitrogenous groups; GO:1901265 nucleoside phosphate binding; GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors; GO:0015631 tubulin binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0048037 cofactor binding; GO:0016491 oxidoreductase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity; GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; GO:0042802 identical protein binding; GO:0008092 cytoskeletal protein binding; GO:0051287 NAD binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0008017 microtubule binding; GO:0050661 NADP binding; GO:0035605 peptidyl-cysteine S-nitrosylase activity; GO:0016740 transferase activity; GO:0036094 small molecule binding; GO:0050662 coenzyme binding; GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity; ","K00134","GAPDH; glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12]","hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04066 HIF-1 signaling pathway - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human); hsa01230 Biosynthesis of amino acids - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); ","IPR020829; IPR016040; IPR020828; ","\"Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; NAD(P)-binding domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; \"\r"]
["P04424","Argininosuccinate lyase OS=Homo sapiens OX=9606 GN=ASL","ASL",51.657,15.335,9.7,3,3,3,1.012,1.027,1.004,0.954,0.962,1.05,0.975,0.445,"cytoplasm\r","GO:0006526 arginine biosynthetic process; GO:0016053 organic acid biosynthetic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:0009084 glutamine family amino acid biosynthetic process; GO:0071704 organic substance metabolic process; GO:0071941 nitrogen cycle metabolic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:1901607 alpha-amino acid biosynthetic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0042450 arginine biosynthetic process via ornithine; GO:0000050 urea cycle; GO:0009987 cellular process; GO:0009064 glutamine family amino acid metabolic process; GO:0008652 cellular amino acid biosynthetic process; GO:0019627 urea metabolic process; GO:0044711 single-organism biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006525 arginine metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0044238 primary metabolic process; GO:1901605 alpha-amino acid metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0006591 ornithine metabolic process; GO:0046394 carboxylic acid biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0044710 single-organism metabolic process; GO:0044283 small molecule biosynthetic process; GO:0019752 carboxylic acid metabolic process; GO:0043604 amide biosynthetic process; GO:0006082 organic acid metabolic process; GO:0043436 oxoacid metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016840 carbon-nitrogen lyase activity; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016829 lyase activity; GO:0004056 argininosuccinate lyase activity; GO:0005515 protein binding; GO:0016842 amidine-lyase activity; ","K01755","argH; argininosuccinate lyase [EC:4.3.2.1]","hsa00220 Arginine biosynthesis - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00250 Alanine, aspartate and glutamate metabolism - Homo sapiens (human); hsa01230 Biosynthesis of amino acids - Homo sapiens (human); ","IPR029419; IPR024083; IPR008948; IPR022761; ","\"Argininosuccinate lyase, C-terminal; Fumarase/histidase, N-terminal; L-Aspartase-like; Fumarate lyase, N-terminal; \"\r"]
["P04632","Calpain small subunit 1 OS=Homo sapiens OX=9606 GN=CAPNS1","CAPNS1",28.315,66.871,23.9,5,12,4,1.085,1.118,1.004,0.944,0.951,0.964,0.891,0.0251,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0042127 regulation of cell proliferation; GO:0031424 keratinization; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0071704 organic substance metabolic process; GO:0009913 epidermal cell differentiation; GO:0008152 metabolic process; GO:0030154 cell differentiation; GO:0043062 extracellular structure organization; GO:0022617 extracellular matrix disassembly; GO:0008544 epidermis development; GO:0006508 proteolysis; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0030198 extracellular matrix organization; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0043588 skin development; GO:0009888 tissue development; GO:0030216 keratinocyte differentiation; GO:0031329 regulation of cellular catabolic process; GO:0048731 system development; GO:0009894 regulation of catabolic process; GO:0070268 cornification; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0044238 primary metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0048518 positive regulation of biological process; GO:0010506 regulation of autophagy; GO:0032501 multicellular organismal process; GO:0016241 regulation of macroautophagy; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0022411 cellular component disassembly; GO:0019222 regulation of metabolic process; GO:0012501 programmed cell death; GO:0048856 anatomical structure development; GO:0008284 positive regulation of cell proliferation; GO:0071840 cellular component organization or biogenesis; GO:0030855 epithelial cell differentiation; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0004175 endopeptidase activity; GO:0004198 calcium-dependent cysteine-type endopeptidase activity; GO:0008233 peptidase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0008234 cysteine-type peptidase activity; GO:0005509 calcium ion binding; GO:0004197 cysteine-type endopeptidase activity; ","K08583",null,null,"IPR011992; IPR002048; ","EF-hand domain pair; EF-hand domain; \r"]
["P04792","Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1","HSPB1",22.782,139.58,71.7,18,54,18,1.055,1.016,0.995,0.977,0.981,0.975,0.957,0.125,"nucleus\r","GO:0044700 single organism signaling; GO:0098840 protein transport along microtubule; GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0030335 positive regulation of cell migration; GO:0010941 regulation of cell death; GO:0032680 regulation of tumor necrosis factor production; GO:0042108 positive regulation of cytokine biosynthetic process; GO:0007166 cell surface receptor signaling pathway; GO:0010608 posttranscriptional regulation of gene expression; GO:0009891 positive regulation of biosynthetic process; GO:2001026 regulation of endothelial cell chemotaxis; GO:0032760 positive regulation of tumor necrosis factor production; GO:0032651 regulation of interleukin-1 beta production; GO:0015031 protein transport; GO:0010594 regulation of endothelial cell migration; GO:0009607 response to biotic stimulus; GO:0009605 response to external stimulus; GO:0022610 biological adhesion; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0032732 positive regulation of interleukin-1 production; GO:0035966 response to topologically incorrect protein; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling; GO:1904018 positive regulation of vasculature development; GO:0007155 cell adhesion; GO:1905383 protein localization to presynapse; GO:0070848 response to growth factor; GO:0050921 positive regulation of chemotaxis; GO:0044419 interspecies interaction between organisms; GO:0008104 protein localization; GO:0008089 anterograde axonal transport; GO:0044765 single-organism transport; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0010632 regulation of epithelial cell migration; GO:0030168 platelet activation; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0051272 positive regulation of cellular component movement; GO:0031323 regulation of cellular metabolic process; GO:0043086 negative regulation of catalytic activity; GO:0032501 multicellular organismal process; GO:0010506 regulation of autophagy; GO:0051704 multi-organism process; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0006810 transport; GO:0001895 retina homeostasis; GO:1902532 negative regulation of intracellular signal transduction; GO:0080135 regulation of cellular response to stress; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0098602 single organism cell adhesion; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:1903202 negative regulation of oxidative stress-induced cell death; GO:0010604 positive regulation of macromolecule metabolic process; GO:0045765 regulation of angiogenesis; GO:0050817 coagulation; GO:0048010 vascular endothelial growth factor receptor signaling pathway; GO:0060548 negative regulation of cell death; GO:0051094 positive regulation of developmental process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0046907 intracellular transport; GO:0001819 positive regulation of cytokine production; GO:0031399 regulation of protein modification process; GO:0043067 regulation of programmed cell death; GO:0080134 regulation of response to stress; GO:2000147 positive regulation of cell motility; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0034109 homotypic cell-cell adhesion; GO:0060249 anatomical structure homeostasis; GO:0030705 cytoskeleton-dependent intracellular transport; GO:0051239 regulation of multicellular organismal process; GO:0043487 regulation of RNA stability; GO:0038084 vascular endothelial growth factor signaling pathway; GO:0032731 positive regulation of interleukin-1 beta production; GO:0023057 negative regulation of signaling; GO:0099640 axo-dendritic protein transport; GO:0010648 negative regulation of cell communication; GO:1902578 single-organism localization; GO:0009889 regulation of biosynthetic process; GO:2000145 regulation of cell motility; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902580 single-organism cellular localization; GO:0001933 negative regulation of protein phosphorylation; GO:0034613 cellular protein localization; GO:0009966 regulation of signal transduction; GO:0006986 response to unfolded protein; GO:1902531 regulation of intracellular signal transduction; GO:0006950 response to stress; GO:0051270 regulation of cellular component movement; GO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway; GO:0098930 axonal transport; GO:0038089 positive regulation of cell migration by vascular endothelial growth factor signaling pathway; GO:1903557 positive regulation of tumor necrosis factor superfamily cytokine production; GO:0071702 organic substance transport; GO:0032101 regulation of response to external stimulus; GO:0030334 regulation of cell migration; GO:0010033 response to organic substance; GO:0007017 microtubule-based process; GO:0009892 negative regulation of metabolic process; GO:0034248 regulation of cellular amide metabolic process; GO:1900408 negative regulation of cellular response to oxidative stress; GO:0045184 establishment of protein localization; GO:0043535 regulation of blood vessel endothelial cell migration; GO:0051247 positive regulation of protein metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0001775 cell activation; GO:0006928 movement of cell or subcellular component; GO:1902882 regulation of response to oxidative stress; GO:0031328 positive regulation of cellular biosynthetic process; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:0050793 regulation of developmental process; GO:0045936 negative regulation of phosphate metabolic process; GO:1903555 regulation of tumor necrosis factor superfamily cytokine production; GO:0042534 regulation of tumor necrosis factor biosynthetic process; GO:0009968 negative regulation of signal transduction; GO:0040017 positive regulation of locomotion; GO:0061077 chaperone-mediated protein folding; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0071363 cellular response to growth factor stimulus; GO:0048871 multicellular organismal homeostasis; GO:0031400 negative regulation of protein modification process; GO:0051234 establishment of localization; GO:0009611 response to wounding; GO:0006457 protein folding; GO:2001233 regulation of apoptotic signaling pathway; GO:0016337 single organismal cell-cell adhesion; GO:0007165 signal transduction; GO:0010970 transport along microtubule; GO:0010646 regulation of cell communication; GO:0051649 establishment of localization in cell; GO:2001243 negative regulation of intrinsic apoptotic signaling pathway; GO:0007154 cell communication; GO:0071901 negative regulation of protein serine/threonine kinase activity; GO:0009893 positive regulation of metabolic process; GO:0033673 negative regulation of kinase activity; GO:0032103 positive regulation of response to external stimulus; GO:0033036 macromolecule localization; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0043536 positive regulation of blood vessel endothelial cell migration; GO:0070887 cellular response to chemical stimulus; GO:2001028 positive regulation of endothelial cell chemotaxis; GO:0042035 regulation of cytokine biosynthetic process; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0099641 anterograde axonal protein transport; GO:0098609 cell-cell adhesion; GO:0048522 positive regulation of cellular process; GO:0051348 negative regulation of transferase activity; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:1902582 single-organism intracellular transport; GO:0008088 axo-dendritic transport; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0042221 response to chemical; GO:1902883 negative regulation of response to oxidative stress; GO:0001894 tissue homeostasis; GO:0006469 negative regulation of protein kinase activity; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0099118 microtubule-based protein transport; GO:0019220 regulation of phosphate metabolic process; GO:0009615 response to virus; GO:0070527 platelet aggregation; GO:0043549 regulation of kinase activity; GO:2000026 regulation of multicellular organismal development; GO:0045859 regulation of protein kinase activity; GO:0043069 negative regulation of programmed cell death; GO:0035418 protein localization to synapse; GO:0010595 positive regulation of endothelial cell migration; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:1903201 regulation of oxidative stress-induced cell death; GO:0043207 response to external biotic stimulus; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0045766 positive regulation of angiogenesis; GO:0007599 hemostasis; GO:0099111 microtubule-based transport; GO:0042592 homeostatic process; GO:0043066 negative regulation of apoptotic process; GO:0016032 viral process; GO:0042326 negative regulation of phosphorylation; GO:0006886 intracellular protein transport; GO:0009987 cellular process; GO:0032652 regulation of interleukin-1 production; GO:0050878 regulation of body fluid levels; GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway; GO:0035924 cellular response to vascular endothelial growth factor stimulus; GO:0035556 intracellular signal transduction; GO:0001932 regulation of protein phosphorylation; GO:1901342 regulation of vasculature development; GO:0010556 regulation of macromolecule biosynthetic process; GO:0010634 positive regulation of epithelial cell migration; GO:0048585 negative regulation of response to stimulus; GO:0050920 regulation of chemotaxis; GO:0043488 regulation of mRNA stability; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:1902176 negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway; GO:0007018 microtubule-based movement; GO:0070727 cellular macromolecule localization; GO:0042060 wound healing; GO:1900407 regulation of cellular response to oxidative stress; GO:0006417 regulation of translation; GO:0051246 regulation of protein metabolic process; GO:2001242 regulation of intrinsic apoptotic signaling pathway; GO:0010563 negative regulation of phosphorus metabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0042535 positive regulation of tumor necrosis factor biosynthetic process; GO:0006446 regulation of translational initiation; GO:0051248 negative regulation of protein metabolic process; GO:0001817 regulation of cytokine production; GO:0040012 regulation of locomotion; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0030016 myofibril; GO:0099568 cytoplasmic region; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032838 cell projection cytoplasm; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0030018 Z disc; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0031674 I band; GO:0044422 organelle part; GO:1905369 endopeptidase complex; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:1902494 catalytic complex; GO:0005925 focal adhesion; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0043292 contractile fiber; GO:0043005 neuron projection; GO:0030055 cell-substrate junction; GO:1905368 peptidase complex; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0005924 cell-substrate adherens junction; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0000502 proteasome complex; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0044463 cell projection part; GO:0005829 cytosol; GO:0005819 spindle; GO:0005576 extracellular region; GO:0033267 axon part; GO:0005886 plasma membrane; GO:0099081 supramolecular polymer; GO:0043231 intracellular membrane-bounded organelle; GO:0030424 axon; GO:0031012 extracellular matrix; GO:0043226 organelle; GO:0005634 nucleus; GO:1904115 axon cytoplasm; GO:0030017 sarcomere; GO:0044449 contractile fiber part; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0030291 protein serine/threonine kinase inhibitor activity; GO:0003723 RNA binding; GO:0019901 protein kinase binding; GO:0004860 protein kinase inhibitor activity; GO:0008426 protein kinase C inhibitor activity; GO:0005515 protein binding; GO:0019207 kinase regulator activity; GO:0019887 protein kinase regulator activity; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0019900 kinase binding; GO:0032182 ubiquitin-like protein binding; GO:0044183 protein binding involved in protein folding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0042802 identical protein binding; GO:0030234 enzyme regulator activity; GO:0019210 kinase inhibitor activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0043130 ubiquitin binding; GO:0005080 protein kinase C binding; GO:0019899 enzyme binding; ","K04455","HSPB1; heat shock protein beta-1","hsa04010 MAPK signaling pathway - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); hsa04370 VEGF signaling pathway - Homo sapiens (human); hsa05146 Amoebiasis - Homo sapiens (human); ","IPR002068; IPR008978; ","Alpha crystallin/Hsp20 domain; HSP20-like chaperone; \r"]
["P04839","Cytochrome b-245 heavy chain OS=Homo sapiens OX=9606 GN=CYBB","CYBB",65.335,12.781,9.5,5,5,5,0.806,0.899,0.763,1.125,1.118,1.275,1.425,5.3E-3,"plasma membrane\r","GO:0044700 single organism signaling; GO:0006801 superoxide metabolic process; GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0007166 cell surface receptor signaling pathway; GO:0032680 regulation of tumor necrosis factor production; GO:0042108 positive regulation of cytokine biosynthetic process; GO:0009891 positive regulation of biosynthetic process; GO:0032760 positive regulation of tumor necrosis factor production; GO:0044237 cellular metabolic process; GO:0051385 response to mineralocorticoid; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:1904018 positive regulation of vasculature development; GO:0048545 response to steroid hormone; GO:0009719 response to endogenous stimulus; GO:1901652 response to peptide; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0080090 regulation of primary metabolic process; GO:0000302 response to reactive oxygen species; GO:0043269 regulation of ion transport; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0097306 cellular response to alcohol; GO:0031323 regulation of cellular metabolic process; GO:0034762 regulation of transmembrane transport; GO:0006810 transport; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0010243 response to organonitrogen compound; GO:0044710 single-organism metabolic process; GO:0071230 cellular response to amino acid stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:1901698 response to nitrogen compound; GO:0010604 positive regulation of macromolecule metabolic process; GO:0045765 regulation of angiogenesis; GO:0048010 vascular endothelial growth factor receptor signaling pathway; GO:0051094 positive regulation of developmental process; GO:0050665 hydrogen peroxide biosynthetic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0002283 neutrophil activation involved in immune response; GO:0001819 positive regulation of cytokine production; GO:0009628 response to abiotic stimulus; GO:0045454 cell redox homeostasis; GO:1901700 response to oxygen-containing compound; GO:0051239 regulation of multicellular organismal process; GO:0042493 response to drug; GO:0042743 hydrogen peroxide metabolic process; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0071229 cellular response to acid chemical; GO:0009889 regulation of biosynthetic process; GO:0070482 response to oxygen levels; GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; GO:0071456 cellular response to hypoxia; GO:1903409 reactive oxygen species biosynthetic process; GO:0006950 response to stress; GO:0016192 vesicle-mediated transport; GO:1903557 positive regulation of tumor necrosis factor superfamily cytokine production; GO:0097305 response to alcohol; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0007584 response to nutrient; GO:0002263 cell activation involved in immune response; GO:0045055 regulated exocytosis; GO:0051247 positive regulation of protein metabolic process; GO:0006811 ion transport; GO:0031325 positive regulation of cellular metabolic process; GO:0045730 respiratory burst; GO:0001775 cell activation; GO:0036293 response to decreased oxygen levels; GO:0031328 positive regulation of cellular biosynthetic process; GO:0051179 localization; GO:0006955 immune response; GO:0071248 cellular response to metal ion; GO:0050793 regulation of developmental process; GO:0006887 exocytosis; GO:1903555 regulation of tumor necrosis factor superfamily cytokine production; GO:0001101 response to acid chemical; GO:0042534 regulation of tumor necrosis factor biosynthetic process; GO:1904044 response to aldosterone; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0097411 hypoxia-inducible factor-1alpha signaling pathway; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I; GO:0006979 response to oxidative stress; GO:0046686 response to cadmium ion; GO:0010035 response to inorganic substance; GO:1904844 response to L-glutamine; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0070887 cellular response to chemical stimulus; GO:0002274 myeloid leukocyte activation; GO:0042035 regulation of cytokine biosynthetic process; GO:0043200 response to amino acid; GO:0031326 regulation of cellular biosynthetic process; GO:0055114 oxidation-reduction process; GO:0048002 antigen processing and presentation of peptide antigen; GO:0002446 neutrophil mediated immunity; GO:0048522 positive regulation of cellular process; GO:0019725 cellular homeostasis; GO:0023052 signaling; GO:0010038 response to metal ion; GO:0002444 myeloid leukocyte mediated immunity; GO:0071417 cellular response to organonitrogen compound; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0043434 response to peptide hormone; GO:1901699 cellular response to nitrogen compound; GO:0032940 secretion by cell; GO:0006954 inflammatory response; GO:0019222 regulation of metabolic process; GO:0071241 cellular response to inorganic substance; GO:0006952 defense response; GO:0043299 leukocyte degranulation; GO:2000026 regulation of multicellular organismal development; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0045471 response to ethanol; GO:0050896 response to stimulus; GO:0045766 positive regulation of angiogenesis; GO:1904845 cellular response to L-glutamine; GO:0071276 cellular response to cadmium ion; GO:0045087 innate immune response; GO:0071361 cellular response to ethanol; GO:0042592 homeostatic process; GO:0033993 response to lipid; GO:0009991 response to extracellular stimulus; GO:0072593 reactive oxygen species metabolic process; GO:0001666 response to hypoxia; GO:0031960 response to corticosteroid; GO:0036230 granulocyte activation; GO:0071453 cellular response to oxygen levels; GO:0009987 cellular process; GO:0051049 regulation of transport; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:1901342 regulation of vasculature development; GO:0010556 regulation of macromolecule biosynthetic process; GO:1990776 response to angiotensin; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0042554 superoxide anion generation; GO:0044249 cellular biosynthetic process; GO:0002366 leukocyte activation involved in immune response; GO:0019882 antigen processing and presentation; GO:0042119 neutrophil activation; GO:1901701 cellular response to oxygen-containing compound; GO:0034765 regulation of ion transmembrane transport; GO:0051246 regulation of protein metabolic process; GO:0071495 cellular response to endogenous stimulus; GO:0022603 regulation of anatomical structure morphogenesis; GO:0042535 positive regulation of tumor necrosis factor biosynthetic process; GO:0001817 regulation of cytokine production; GO:0031667 response to nutrient levels; GO:0009725 response to hormone; GO:0036294 cellular response to decreased oxygen levels; GO:1901654 response to ketone; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0030425 dendrite; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0043025 neuronal cell body; GO:0032991 macromolecular complex; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0043005 neuron projection; GO:0043020 NADPH oxidase complex; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0005789 endoplasmic reticulum membrane; GO:0042995 cell projection; GO:0031226 intrinsic component of plasma membrane; GO:0005791 rough endoplasmic reticulum; GO:0030666 endocytic vesicle membrane; GO:0031967 organelle envelope; GO:0012506 vesicle membrane; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0030667 secretory granule membrane; GO:0031975 envelope; GO:1990204 oxidoreductase complex; GO:0005783 endoplasmic reticulum; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0070821 tertiary granule membrane; GO:1902494 catalytic complex; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0030670 phagocytic vesicle membrane; GO:0048471 perinuclear region of cytoplasm; GO:0030141 secretory granule; GO:0030139 endocytic vesicle; GO:0035579 specific granule membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0005635 nuclear envelope; GO:0070820 tertiary granule; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0045335 phagocytic vesicle; GO:0016021 integral component of membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0044432 endoplasmic reticulum part; GO:0042581 specific granule; GO:0044297 cell body; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0050660 flavin adenine dinucleotide binding; GO:0022803 passive transmembrane transporter activity; GO:0046983 protein dimerization activity; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0015267 channel activity; GO:0016175 superoxide-generating NADPH oxidase activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0020037 heme binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043169 cation binding; GO:0005216 ion channel activity; GO:0043168 anion binding; GO:0046906 tetrapyrrole binding; GO:0005215 transporter activity; GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:0046982 protein heterodimerization activity; GO:0015075 ion transmembrane transporter activity; GO:0043167 ion binding; GO:0000166 nucleotide binding; GO:0048037 cofactor binding; GO:0016491 oxidoreductase activity; GO:0005244 voltage-gated ion channel activity; GO:0022838 substrate-specific channel activity; GO:0046872 metal ion binding; GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor; GO:0022836 gated channel activity; GO:0022832 voltage-gated channel activity; GO:0022857 transmembrane transporter activity; GO:0036094 small molecule binding; GO:0050662 coenzyme binding; ","K08008","NOX1; NADPH oxidase 1","hsa04380 Osteoclast differentiation - Homo sapiens (human); hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human); hsa04933 AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human); ","IPR017927; IPR013121; IPR013112; IPR017938; IPR013130; ","\"Ferredoxin reductase-type FAD-binding domain; Ferric reductase, NAD binding domain; FAD-binding 8; Riboflavin synthase-like beta-barrel; Ferric reductase transmembrane component-like domain; \"\r"]
["P04843","Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1","RPN1",68.569,120.95,42.8,26,52,26,1.05,1.039,1.056,0.964,0.936,0.95,0.906,0.000539,"endoplasmic reticulum\r","GO:0043413 macromolecule glycosylation; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0018196 peptidyl-asparagine modification; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:1901135 carbohydrate derivative metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006487 protein N-linked glycosylation; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0070085 glycosylation; GO:0006486 protein glycosylation; GO:0009101 glycoprotein biosynthetic process; GO:0044763 single-organism cellular process; GO:0009100 glycoprotein metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0018193 peptidyl-amino acid modification; GO:0018279 protein N-linked glycosylation via asparagine; GO:0034645 cellular macromolecule biosynthetic process; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0036211 protein modification process; GO:0043412 macromolecule modification; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0048770 pigment granule; GO:1902494 catalytic complex; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0005791 rough endoplasmic reticulum; GO:0042470 melanosome; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:1990234 transferase complex; GO:0008250 oligosaccharyltransferase complex; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0031012 extracellular matrix; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044432 endoplasmic reticulum part; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity; GO:0016758 transferase activity, transferring hexosyl groups; GO:0003824 catalytic activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0016757 transferase activity, transferring glycosyl groups; GO:0016740 transferase activity; GO:0004576 oligosaccharyl transferase activity; ","K12666","OST1; oligosaccharyltransferase complex subunit alpha (ribophorin I)","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00510 N-Glycan biosynthesis - Homo sapiens (human); hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); "]
["P04844","Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 OS=Homo sapiens OX=9606 GN=RPN2","RPN2",69.283,122.84,16,9,19,9,1.065,1.05,1.061,0.95,0.937,0.992,0.906,0.00512,"extracellular\r","GO:0043413 macromolecule glycosylation; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0018196 peptidyl-asparagine modification; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0042493 response to drug; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:1901135 carbohydrate derivative metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006487 protein N-linked glycosylation; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0070085 glycosylation; GO:0032502 developmental process; GO:0006486 protein glycosylation; GO:0009101 glycoprotein biosynthetic process; GO:0044763 single-organism cellular process; GO:0009100 glycoprotein metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0018193 peptidyl-amino acid modification; GO:0018279 protein N-linked glycosylation via asparagine; GO:0042221 response to chemical; GO:0034645 cellular macromolecule biosynthetic process; GO:0044767 single-organism developmental process; GO:0044710 single-organism metabolic process; GO:0007568 aging; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0036211 protein modification process; GO:0043412 macromolecule modification; ","GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005776 autophagosome; GO:1902494 catalytic complex; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0000421 autophagosome membrane; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0005791 rough endoplasmic reticulum; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:1990234 transferase complex; GO:0008250 oligosaccharyltransferase complex; GO:0016021 integral component of membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044432 endoplasmic reticulum part; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0044444 cytoplasmic part; ","GO:0043022 ribosome binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0005515 protein binding; GO:0016757 transferase activity, transferring glycosyl groups; GO:0016740 transferase activity; GO:0043021 ribonucleoprotein complex binding; ","K12667","SWP1; oligosaccharyltransferase complex subunit delta (ribophorin II)","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00510 N-Glycan biosynthesis - Homo sapiens (human); hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); "]
["P04899","Guanine nucleotide-binding protein G(i) subunit alpha-2 OS=Homo sapiens OX=9606 GN=GNAI2","GNAI2",40.45,158.02,54.4,15,32,8,1.019,1.052,1.059,0.96,0.956,0.962,0.919,0.02,"cytoplasm\r","GO:0044700 single organism signaling; GO:0030815 negative regulation of cAMP metabolic process; GO:0032270 positive regulation of cellular protein metabolic process; GO:0045980 negative regulation of nucleotide metabolic process; GO:0007166 cell surface receptor signaling pathway; GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; GO:0009605 response to external stimulus; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0051347 positive regulation of transferase activity; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0051174 regulation of phosphorus metabolic process; GO:0060359 response to ammonium ion; GO:0080090 regulation of primary metabolic process; GO:0035588 G-protein coupled purinergic receptor signaling pathway; GO:0044763 single-organism cellular process; GO:0043269 regulation of ion transport; GO:0043086 negative regulation of catalytic activity; GO:0071242 cellular response to ammonium ion; GO:0031323 regulation of cellular metabolic process; GO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway; GO:0051339 regulation of lyase activity; GO:0031279 regulation of cyclase activity; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0010604 positive regulation of macromolecule metabolic process; GO:0030809 negative regulation of nucleotide biosynthetic process; GO:0051301 cell division; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0006140 regulation of nucleotide metabolic process; GO:1905144 response to acetylcholine; GO:0050794 regulation of cellular process; GO:0042127 regulation of cell proliferation; GO:0031399 regulation of protein modification process; GO:1901700 response to oxygen-containing compound; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0023057 negative regulation of signaling; GO:0045761 regulation of adenylate cyclase activity; GO:0010648 negative regulation of cell communication; GO:0032147 activation of protein kinase activity; GO:0009889 regulation of biosynthetic process; GO:0030817 regulation of cAMP biosynthetic process; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0010959 regulation of metal ion transport; GO:0035587 purinergic receptor signaling pathway; GO:0009966 regulation of signal transduction; GO:0031280 negative regulation of cyclase activity; GO:1902531 regulation of intracellular signal transduction; GO:0051350 negative regulation of lyase activity; GO:0050804 modulation of synaptic transmission; GO:0051924 regulation of calcium ion transport; GO:0008283 cell proliferation; GO:0007194 negative regulation of adenylate cyclase activity; GO:0010033 response to organic substance; GO:0007584 response to nutrient; GO:0009892 negative regulation of metabolic process; GO:0030799 regulation of cyclic nucleotide metabolic process; GO:0007186 G-protein coupled receptor signaling pathway; GO:0009890 negative regulation of biosynthetic process; GO:0051247 positive regulation of protein metabolic process; GO:1900543 negative regulation of purine nucleotide metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0095500 acetylcholine receptor signaling pathway; GO:0048584 positive regulation of response to stimulus; GO:0045936 negative regulation of phosphate metabolic process; GO:0008284 positive regulation of cell proliferation; GO:1900372 negative regulation of purine nucleotide biosynthetic process; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0000186 activation of MAPKK activity; GO:0006457 protein folding; GO:0007213 G-protein coupled acetylcholine receptor signaling pathway; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0030814 regulation of cAMP metabolic process; GO:0033674 positive regulation of kinase activity; GO:0070887 cellular response to chemical stimulus; GO:0030808 regulation of nucleotide biosynthetic process; GO:0045937 positive regulation of phosphate metabolic process; GO:0050805 negative regulation of synaptic transmission; GO:0030802 regulation of cyclic nucleotide biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0048522 positive regulation of cellular process; GO:1905145 cellular response to acetylcholine; GO:0023052 signaling; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0042221 response to chemical; GO:1901699 cellular response to nitrogen compound; GO:1900371 regulation of purine nucleotide biosynthetic process; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:1903831 signal transduction involved in cellular response to ammonium ion; GO:0043549 regulation of kinase activity; GO:0045859 regulation of protein kinase activity; GO:0007214 gamma-aminobutyric acid signaling pathway; GO:0001973 adenosine receptor signaling pathway; GO:0060255 regulation of macromolecule metabolic process; GO:0043405 regulation of MAP kinase activity; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0030803 negative regulation of cyclic nucleotide biosynthetic process; GO:0009991 response to extracellular stimulus; GO:0043408 regulation of MAPK cascade; GO:0023056 positive regulation of signaling; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:0035556 intracellular signal transduction; GO:0051049 regulation of transport; GO:0001932 regulation of protein phosphorylation; GO:0031401 positive regulation of protein modification process; GO:0030800 negative regulation of cyclic nucleotide metabolic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0045860 positive regulation of protein kinase activity; GO:0001934 positive regulation of protein phosphorylation; GO:0048518 positive regulation of biological process; GO:0030818 negative regulation of cAMP biosynthetic process; GO:0043085 positive regulation of catalytic activity; GO:1900542 regulation of purine nucleotide metabolic process; GO:1901701 cellular response to oxygen-containing compound; GO:0051246 regulation of protein metabolic process; GO:0010563 negative regulation of phosphorus metabolic process; GO:0031667 response to nutrient levels; GO:0031327 negative regulation of cellular biosynthetic process; GO:0009967 positive regulation of signal transduction; GO:0043410 positive regulation of MAPK cascade; GO:0007049 cell cycle; GO:0065007 biological regulation; GO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; ","GO:0016020 membrane; GO:0030425 dendrite; GO:0044421 extracellular region part; GO:0019898 extrinsic component of membrane; GO:0098857 membrane microdomain; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0031234 extrinsic component of cytoplasmic side of plasma membrane; GO:0005623 cell; GO:0009898 cytoplasmic side of plasma membrane; GO:0098562 cytoplasmic side of membrane; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:1902494 catalytic complex; GO:0005815 microtubule organizing center; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005834 heterotrimeric G-protein complex; GO:0015630 microtubule cytoskeleton; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0098805 whole membrane; GO:0098589 membrane region; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0045121 membrane raft; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043233 organelle lumen; GO:0098552 side of membrane; GO:0043229 intracellular organelle; GO:1905360 GTPase complex; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0098797 plasma membrane protein complex; GO:0044446 intracellular organelle part; GO:0030496 midbody; GO:0019897 extrinsic component of plasma membrane; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0036477 somatodendritic compartment; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0005813 centrosome; GO:0044297 cell body; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0005102 receptor binding; GO:0031683 G-protein beta/gamma-subunit complex binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0004871 signal transducer activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0003924 GTPase activity; GO:0043169 cation binding; GO:0043168 anion binding; GO:0001664 G-protein coupled receptor binding; GO:0019001 guanyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005525 GTP binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0017076 purine nucleotide binding; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0046872 metal ion binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0032561 guanyl ribonucleotide binding; GO:0032403 protein complex binding; GO:0036094 small molecule binding; ","K04630","GNAI; guanine nucleotide-binding protein G(i) subunit alpha","hsa04015 Rap1 signaling pathway - Homo sapiens (human); hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human); hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human); hsa04924 Renin secretion - Homo sapiens (human); hsa04724 Glutamatergic synapse - Homo sapiens (human); hsa05145 Toxoplasmosis - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa04934 Cushing's syndrome - Homo sapiens (human); hsa04071 Sphingolipid signaling pathway - Homo sapiens (human); hsa04611 Platelet activation - Homo sapiens (human); hsa05034 Alcoholism - Homo sapiens (human); hsa04971 Gastric acid secretion - Homo sapiens (human); hsa04914 Progesterone-mediated oocyte maturation - Homo sapiens (human); hsa04915 Estrogen signaling pathway - Homo sapiens (human); hsa05032 Morphine addiction - Homo sapiens (human); hsa04725 Cholinergic synapse - Homo sapiens (human); hsa04921 Oxytocin signaling pathway - Homo sapiens (human); hsa05142 Chagas disease (American trypanosomiasis) - Homo sapiens (human); hsa04728 Dopaminergic synapse - Homo sapiens (human); hsa04371 Apelin signaling pathway - Homo sapiens (human); hsa04916 Melanogenesis - Homo sapiens (human); hsa04923 Regulation of lipolysis in adipocytes - Homo sapiens (human); hsa04024 cAMP signaling pathway - Homo sapiens (human); hsa04670 Leukocyte transendothelial migration - Homo sapiens (human); hsa05030 Cocaine addiction - Homo sapiens (human); hsa04726 Serotonergic synapse - Homo sapiens (human); hsa04062 Chemokine signaling pathway - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human); hsa04540 Gap junction - Homo sapiens (human); hsa04727 GABAergic synapse - Homo sapiens (human); hsa04730 Long-term depression - Homo sapiens (human); hsa05133 Pertussis - Homo sapiens (human); hsa04360 Axon guidance - Homo sapiens (human); hsa04926 Relaxin signaling pathway - Homo sapiens (human); hsa04928 Parathyroid hormone synthesis, secretion and action - Homo sapiens (human); hsa04713 Circadian entrainment - Homo sapiens (human); ","IPR027417; IPR011025; ","\"P-loop containing nucleoside triphosphate hydrolase; G protein alpha subunit, helical insertion; \"\r"]
["P04921","Glycophorin-C OS=Homo sapiens OX=9606 GN=GYPC","GYPC",13.81,21.087,27.3,2,3,2,0.846,0.844,0.944,1.056,1.145,1.076,1.244,0.00776,"plasma membrane\r","GO:0016477 cell migration; GO:0051674 localization of cell; GO:0098609 cell-cell adhesion; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0002376 immune system process; GO:0048870 cell motility; GO:0008037 cell recognition; GO:0022610 biological adhesion; GO:0050900 leukocyte migration; GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; GO:0006928 movement of cell or subcellular component; GO:0007155 cell adhesion; GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules; GO:0040011 locomotion; GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules; GO:0051179 localization; GO:0009987 cellular process; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0031226 intrinsic component of plasma membrane; GO:0005938 cell cortex; GO:0043232 intracellular non-membrane-bounded organelle; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0099568 cytoplasmic region; GO:0070161 anchoring junction; GO:0030863 cortical cytoskeleton; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005913 cell-cell adherens junction; GO:0005887 integral component of plasma membrane; GO:0005911 cell-cell junction; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0005856 cytoskeleton; GO:0044459 plasma membrane part; GO:0044425 membrane part; GO:0044448 cell cortex part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005912 adherens junction; GO:0044444 cytoplasmic part; ","GO:0050839 cell adhesion molecule binding; GO:0060089 molecular transducer activity; GO:0042802 identical protein binding; GO:0004872 receptor activity; GO:0005102 receptor binding; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0046983 protein dimerization activity; GO:0005515 protein binding; ","K06576","GYPC; glycophorin C","hsa05144 Malaria - Homo sapiens (human); ","IPR003585; ","Neurexin/syndecan/glycophorin C; \r"]
["P05023","Sodium/potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1","ATP1A1",112.89,318.42,38.3,39,91,39,1.108,1.057,1.107,0.918,0.912,0.928,0.843,0.000479,"plasma membrane\r","GO:0044700 single organism signaling; GO:0032353 negative regulation of hormone biosynthetic process; GO:0065008 regulation of biological quality; GO:0055075 potassium ion homeostasis; GO:0030004 cellular monovalent inorganic cation homeostasis; GO:0045933 positive regulation of muscle contraction; GO:0019216 regulation of lipid metabolic process; GO:0044237 cellular metabolic process; GO:0061337 cardiac conduction; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0010107 potassium ion import; GO:1903115 regulation of actin filament-based movement; GO:0055065 metal ion homeostasis; GO:0048545 response to steroid hormone; GO:0044057 regulation of system process; GO:0009719 response to endogenous stimulus; GO:0086011 membrane repolarization during action potential; GO:0055078 sodium ion homeostasis; GO:0010248 establishment or maintenance of transmembrane electrochemical gradient; GO:0044765 single-organism transport; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0071214 cellular response to abiotic stimulus; GO:0080090 regulation of primary metabolic process; GO:0043269 regulation of ion transport; GO:0044763 single-organism cellular process; GO:0006941 striated muscle contraction; GO:0031323 regulation of cellular metabolic process; GO:0098657 import into cell; GO:0032501 multicellular organismal process; GO:0006814 sodium ion transport; GO:0071396 cellular response to lipid; GO:1903779 regulation of cardiac conduction; GO:0006810 transport; GO:0046890 regulation of lipid biosynthetic process; GO:0098739 import across plasma membrane; GO:0010817 regulation of hormone levels; GO:0099622 cardiac muscle cell membrane repolarization; GO:0003015 heart process; GO:0003013 circulatory system process; GO:0098662 inorganic cation transmembrane transport; GO:0050794 regulation of cellular process; GO:0086013 membrane repolarization during cardiac muscle cell action potential; GO:0044707 single-multicellular organism process; GO:0002028 regulation of sodium ion transport; GO:0034220 ion transmembrane transport; GO:0009628 response to abiotic stimulus; GO:0030001 metal ion transport; GO:1903416 response to glycoside; GO:0071804 cellular potassium ion transport; GO:1901700 response to oxygen-containing compound; GO:0045822 negative regulation of heart contraction; GO:0019218 regulation of steroid metabolic process; GO:1903523 negative regulation of blood circulation; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0051239 regulation of multicellular organismal process; GO:0042493 response to drug; GO:0086003 cardiac muscle cell contraction; GO:1902578 single-organism localization; GO:0009889 regulation of biosynthetic process; GO:0010959 regulation of metal ion transport; GO:0031946 regulation of glucocorticoid biosynthetic process; GO:0048878 chemical homeostasis; GO:0010644 cell communication by electrical coupling; GO:0051270 regulation of cellular component movement; GO:0071436 sodium ion export; GO:0030007 cellular potassium ion homeostasis; GO:0032970 regulation of actin filament-based process; GO:0071496 cellular response to external stimulus; GO:0071407 cellular response to organic cyclic compound; GO:0086064 cell communication by electrical coupling involved in cardiac conduction; GO:0010033 response to organic substance; GO:0009892 negative regulation of metabolic process; GO:0055085 transmembrane transport; GO:0009890 negative regulation of biosynthetic process; GO:0031943 regulation of glucocorticoid metabolic process; GO:0006793 phosphorus metabolic process; GO:0006873 cellular ion homeostasis; GO:0006811 ion transport; GO:0030029 actin filament-based process; GO:0006928 movement of cell or subcellular component; GO:0090032 negative regulation of steroid hormone biosynthetic process; GO:0051179 localization; GO:0032351 negative regulation of hormone metabolic process; GO:0015672 monovalent inorganic cation transport; GO:0030048 actin filament-based movement; GO:0086009 membrane repolarization; GO:0070252 actin-mediated cell contraction; GO:0003012 muscle system process; GO:0090662 ATP hydrolysis coupled transmembrane transport; GO:0090030 regulation of steroid hormone biosynthetic process; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0051241 negative regulation of multicellular organismal process; GO:0055119 relaxation of cardiac muscle; GO:0071383 cellular response to steroid hormone stimulus; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0006813 potassium ion transport; GO:0007154 cell communication; GO:0050810 regulation of steroid biosynthetic process; GO:0055117 regulation of cardiac muscle contraction; GO:0001508 action potential; GO:0070887 cellular response to chemical stimulus; GO:0045833 negative regulation of lipid metabolic process; GO:0051055 negative regulation of lipid biosynthetic process; GO:0098655 cation transmembrane transport; GO:0031326 regulation of cellular biosynthetic process; GO:0050801 ion homeostasis; GO:0098771 inorganic ion homeostasis; GO:0035637 multicellular organismal signaling; GO:0019725 cellular homeostasis; GO:0090257 regulation of muscle system process; GO:0045989 positive regulation of striated muscle contraction; GO:0023052 signaling; GO:0006883 cellular sodium ion homeostasis; GO:0006942 regulation of striated muscle contraction; GO:0042391 regulation of membrane potential; GO:0045939 negative regulation of steroid metabolic process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0086001 cardiac muscle cell action potential; GO:0032870 cellular response to hormone stimulus; GO:0019222 regulation of metabolic process; GO:0071805 potassium ion transmembrane transport; GO:0008217 regulation of blood pressure; GO:0035725 sodium ion transmembrane transport; GO:0071260 cellular response to mechanical stimulus; GO:0030003 cellular cation homeostasis; GO:0071310 cellular response to organic substance; GO:1903522 regulation of blood circulation; GO:0060048 cardiac muscle contraction; GO:0031324 negative regulation of cellular metabolic process; GO:0008016 regulation of heart contraction; GO:0050896 response to stimulus; GO:0055082 cellular chemical homeostasis; GO:1990573 potassium ion import across plasma membrane; GO:0086004 regulation of cardiac muscle cell contraction; GO:0090075 relaxation of muscle; GO:0033993 response to lipid; GO:0042592 homeostatic process; GO:0009612 response to mechanical stimulus; GO:0046885 regulation of hormone biosynthetic process; GO:0006936 muscle contraction; GO:0006812 cation transport; GO:0055080 cation homeostasis; GO:0008015 blood circulation; GO:0060047 heart contraction; GO:1903524 positive regulation of blood circulation; GO:0009987 cellular process; GO:0032350 regulation of hormone metabolic process; GO:0055067 monovalent inorganic cation homeostasis; GO:0003008 system process; GO:0098660 inorganic ion transmembrane transport; GO:0051049 regulation of transport; GO:0006937 regulation of muscle contraction; GO:0031944 negative regulation of glucocorticoid metabolic process; GO:0016311 dephosphorylation; GO:0048518 positive regulation of biological process; GO:0036376 sodium ion export from cell; GO:0045823 positive regulation of heart contraction; GO:0010894 negative regulation of steroid biosynthetic process; GO:0031947 negative regulation of glucocorticoid biosynthetic process; GO:0086002 cardiac muscle cell action potential involved in contraction; GO:0071495 cellular response to endogenous stimulus; GO:0060081 membrane hyperpolarization; GO:0002026 regulation of the force of heart contraction; GO:0006875 cellular metal ion homeostasis; GO:0031327 negative regulation of cellular biosynthetic process; GO:0009725 response to hormone; GO:0065007 biological regulation; GO:0086065 cell communication involved in cardiac conduction; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0098857 membrane microdomain; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0090533 cation-transporting ATPase complex; GO:0014704 intercalated disc; GO:0070062 extracellular exosome; GO:0030315 T-tubule; GO:0098590 plasma membrane region; GO:0005622 intracellular; GO:0043209 myelin sheath; GO:0098589 membrane region; GO:0014069 postsynaptic density; GO:0043227 membrane-bounded organelle; GO:0045177 apical part of cell; GO:0031226 intrinsic component of plasma membrane; GO:0005901 caveola; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0098794 postsynapse; GO:0043234 protein complex; GO:0099572 postsynaptic specialization; GO:0042383 sarcolemma; GO:0043230 extracellular organelle; GO:0016323 basolateral plasma membrane; GO:0005783 endoplasmic reticulum; GO:0016324 apical plasma membrane; GO:0031410 cytoplasmic vesicle; GO:0044291 cell-cell contact zone; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005911 cell-cell junction; GO:0032279 asymmetric synapse; GO:0048770 pigment granule; GO:0098533 ATPase dependent transmembrane transport complex; GO:1902494 catalytic complex; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0045121 membrane raft; GO:1990351 transporter complex; GO:0098984 neuron to neuron synapse; GO:0044456 synapse part; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0042470 melanosome; GO:0012505 endomembrane system; GO:1902495 transmembrane transporter complex; GO:0016021 integral component of membrane; GO:0045202 synapse; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0044853 plasma membrane raft; GO:1904949 ATPase complex; GO:0005890 sodium:potassium-exchanging ATPase complex; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:0042625 ATPase coupled ion transmembrane transporter activity; GO:0042562 hormone binding; GO:0016791 phosphatase activity; GO:0031402 sodium ion binding; GO:0005391 sodium:potassium-exchanging ATPase activity; GO:0015077 monovalent inorganic cation transmembrane transporter activity; GO:0005496 steroid binding; GO:0022891 substrate-specific transmembrane transporter activity; GO:0097159 organic cyclic compound binding; GO:0008092 cytoskeletal protein binding; GO:0019829 cation-transporting ATPase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0043492 ATPase activity, coupled to movement of substances; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043531 ADP binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0031420 alkali metal ion binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:1990239 steroid hormone binding; GO:0005524 ATP binding; GO:0015075 ion transmembrane transporter activity; GO:0051087 chaperone binding; GO:0022853 active ion transmembrane transporter activity; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0043548 phosphatidylinositol 3-kinase binding; GO:0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity; GO:0042578 phosphoric ester hydrolase activity; GO:1901265 nucleoside phosphate binding; GO:0008556 potassium-transporting ATPase activity; GO:0015399 primary active transmembrane transporter activity; GO:0019901 protein kinase binding; GO:0030955 potassium ion binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0030506 ankyrin binding; GO:0016887 ATPase activity; GO:1901363 heterocyclic compound binding; GO:0046873 metal ion transmembrane transporter activity; GO:0016462 pyrophosphatase activity; GO:0008289 lipid binding; GO:0043169 cation binding; GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0022890 inorganic cation transmembrane transporter activity; GO:0015081 sodium ion transmembrane transporter activity; GO:0005215 transporter activity; GO:0017076 purine nucleotide binding; GO:0022804 active transmembrane transporter activity; GO:0043167 ion binding; GO:0019900 kinase binding; GO:0015079 potassium ion transmembrane transporter activity; GO:0032549 ribonucleoside binding; GO:0015662 ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism; GO:0097367 carbohydrate derivative binding; GO:0042626 ATPase activity, coupled to transmembrane movement of substances; GO:0016788 hydrolase activity, acting on ester bonds; GO:0042623 ATPase activity, coupled; GO:0046872 metal ion binding; GO:0019904 protein domain specific binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019899 enzyme binding; GO:0008324 cation transmembrane transporter activity; GO:0022857 transmembrane transporter activity; GO:0036094 small molecule binding; ","K01539","ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9]","hsa04260 Cardiac muscle contraction - Homo sapiens (human); hsa04978 Mineral absorption - Homo sapiens (human); hsa04964 Proximal tubule bicarbonate reclamation - Homo sapiens (human); hsa04973 Carbohydrate digestion and absorption - Homo sapiens (human); hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human); hsa04024 cAMP signaling pathway - Homo sapiens (human); hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human); hsa04976 Bile secretion - Homo sapiens (human); hsa04911 Insulin secretion - Homo sapiens (human); hsa04970 Salivary secretion - Homo sapiens (human); hsa04925 Aldosterone synthesis and secretion - Homo sapiens (human); hsa04960 Aldosterone-regulated sodium reabsorption - Homo sapiens (human); hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human); hsa04972 Pancreatic secretion - Homo sapiens (human); hsa04918 Thyroid hormone synthesis - Homo sapiens (human); hsa04974 Protein digestion and absorption - Homo sapiens (human); hsa04971 Gastric acid secretion - Homo sapiens (human); hsa04961 Endocrine and other factor-regulated calcium reabsorption - Homo sapiens (human); ","IPR023298; IPR004014; IPR008250; IPR023299; IPR006068; IPR023214; ","\"P-type ATPase,  transmembrane domain; Cation-transporting P-type ATPase, N-terminal; P-type ATPase, A  domain; P-type ATPase, cytoplasmic domain N; Cation-transporting P-type ATPase, C-terminal; HAD-like domain; \"\r"]
["P05026","Sodium/potassium-transporting ATPase subunit beta-1 OS=Homo sapiens OX=9606 GN=ATP1B1","ATP1B1",35.061,41.09,30.4,8,15,8,1.319,1.232,1.212,0.719,0.75,0.804,0.604,2.63E-4,"plasma membrane\r","GO:0044700 single organism signaling; GO:0009116 nucleoside metabolic process; GO:0065008 regulation of biological quality; GO:0055075 potassium ion homeostasis; GO:0030004 cellular monovalent inorganic cation homeostasis; GO:1904427 positive regulation of calcium ion transmembrane transport; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0061337 cardiac conduction; GO:0022610 biological adhesion; GO:0008152 metabolic process; GO:1901019 regulation of calcium ion transmembrane transporter activity; GO:0032879 regulation of localization; GO:0010107 potassium ion import; GO:0044093 positive regulation of molecular function; GO:0055065 metal ion homeostasis; GO:0019693 ribose phosphate metabolic process; GO:0007155 cell adhesion; GO:0032414 positive regulation of ion transmembrane transporter activity; GO:0044057 regulation of system process; GO:1903273 regulation of sodium ion export; GO:0008104 protein localization; GO:0086011 membrane repolarization during action potential; GO:0055078 sodium ion homeostasis; GO:0010248 establishment or maintenance of transmembrane electrochemical gradient; GO:0044765 single-organism transport; GO:0051716 cellular response to stimulus; GO:0072657 protein localization to membrane; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0043269 regulation of ion transport; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0006941 striated muscle contraction; GO:2000649 regulation of sodium ion transmembrane transporter activity; GO:0019932 second-messenger-mediated signaling; GO:0048870 cell motility; GO:0007009 plasma membrane organization; GO:0098657 import into cell; GO:0032501 multicellular organismal process; GO:0006874 cellular calcium ion homeostasis; GO:0006814 sodium ion transport; GO:1903779 regulation of cardiac conduction; GO:0034762 regulation of transmembrane transport; GO:0006810 transport; GO:0050900 leukocyte migration; GO:0051336 regulation of hydrolase activity; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0098739 import across plasma membrane; GO:0044860 protein localization to plasma membrane raft; GO:0032781 positive regulation of ATPase activity; GO:1901021 positive regulation of calcium ion transmembrane transporter activity; GO:0099622 cardiac muscle cell membrane repolarization; GO:0009126 purine nucleoside monophosphate metabolic process; GO:0003015 heart process; GO:0032412 regulation of ion transmembrane transporter activity; GO:0003013 circulatory system process; GO:0098662 inorganic cation transmembrane transport; GO:0086013 membrane repolarization during cardiac muscle cell action potential; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0046907 intracellular transport; GO:0002028 regulation of sodium ion transport; GO:0034220 ion transmembrane transport; GO:0034764 positive regulation of transmembrane transport; GO:0009259 ribonucleotide metabolic process; GO:0009628 response to abiotic stimulus; GO:0030001 metal ion transport; GO:0071804 cellular potassium ion transport; GO:1990778 protein localization to cell periphery; GO:0051239 regulation of multicellular organismal process; GO:0046483 heterocycle metabolic process; GO:1902578 single-organism localization; GO:0019722 calcium-mediated signaling; GO:0051345 positive regulation of hydrolase activity; GO:0006139 nucleobase-containing compound metabolic process; GO:0070482 response to oxygen levels; GO:1901135 carbohydrate derivative metabolic process; GO:0010959 regulation of metal ion transport; GO:1902580 single-organism cellular localization; GO:0034613 cellular protein localization; GO:0090150 establishment of protein localization to membrane; GO:0009119 ribonucleoside metabolic process; GO:0048878 chemical homeostasis; GO:0032409 regulation of transporter activity; GO:1904062 regulation of cation transmembrane transport; GO:0051928 positive regulation of calcium ion transport; GO:0010644 cell communication by electrical coupling; GO:1903281 positive regulation of calcium:sodium antiporter activity; GO:1901381 positive regulation of potassium ion transmembrane transport; GO:0006950 response to stress; GO:1901379 regulation of potassium ion transmembrane transport; GO:0071436 sodium ion export; GO:0051924 regulation of calcium ion transport; GO:0002376 immune system process; GO:1903275 positive regulation of sodium ion export; GO:0030007 cellular potassium ion homeostasis; GO:0071702 organic substance transport; GO:0009141 nucleoside triphosphate metabolic process; GO:0086064 cell communication by electrical coupling involved in cardiac conduction; GO:0044238 primary metabolic process; GO:0006163 purine nucleotide metabolic process; GO:0045184 establishment of protein localization; GO:0032594 protein transport within lipid bilayer; GO:0055085 transmembrane transport; GO:0043270 positive regulation of ion transport; GO:0072659 protein localization to plasma membrane; GO:1903278 positive regulation of sodium ion export from cell; GO:0006873 cellular ion homeostasis; GO:0006793 phosphorus metabolic process; GO:1904064 positive regulation of cation transmembrane transport; GO:0006811 ion transport; GO:0061024 membrane organization; GO:0006928 movement of cell or subcellular component; GO:0019637 organophosphate metabolic process; GO:0031647 regulation of protein stability; GO:1902305 regulation of sodium ion transmembrane transport; GO:0036293 response to decreased oxygen levels; GO:0051179 localization; GO:0015672 monovalent inorganic cation transport; GO:0050821 protein stabilization; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling; GO:0086009 membrane repolarization; GO:0010256 endomembrane system organization; GO:0003012 muscle system process; GO:0042278 purine nucleoside metabolic process; GO:0072503 cellular divalent inorganic cation homeostasis; GO:0051674 localization of cell; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0090662 ATP hydrolysis coupled transmembrane transport; GO:0023051 regulation of signaling; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0051668 localization within membrane; GO:1901018 positive regulation of potassium ion transmembrane transporter activity; GO:0055119 relaxation of cardiac muscle; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0006813 potassium ion transport; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0043266 regulation of potassium ion transport; GO:1903276 regulation of sodium ion export from cell; GO:1903279 regulation of calcium:sodium antiporter activity; GO:0007154 cell communication; GO:0055117 regulation of cardiac muscle contraction; GO:0010765 positive regulation of sodium ion transport; GO:1903286 regulation of potassium ion import; GO:0006753 nucleoside phosphate metabolic process; GO:0043268 positive regulation of potassium ion transport; GO:0001508 action potential; GO:0033036 macromolecule localization; GO:0010468 regulation of gene expression; GO:0098655 cation transmembrane transport; GO:0050801 ion homeostasis; GO:0055074 calcium ion homeostasis; GO:0035637 multicellular organismal signaling; GO:0098771 inorganic ion homeostasis; GO:0019725 cellular homeostasis; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0022898 regulation of transmembrane transporter activity; GO:0090257 regulation of muscle system process; GO:0023052 signaling; GO:0006883 cellular sodium ion homeostasis; GO:0009199 ribonucleoside triphosphate metabolic process; GO:1902582 single-organism intracellular transport; GO:0006942 regulation of striated muscle contraction; GO:0042391 regulation of membrane potential; GO:0051050 positive regulation of transport; GO:0050789 regulation of biological process; GO:0086001 cardiac muscle cell action potential; GO:0043462 regulation of ATPase activity; GO:0034767 positive regulation of ion transmembrane transport; GO:2000651 positive regulation of sodium ion transmembrane transporter activity; GO:0019222 regulation of metabolic process; GO:1901016 regulation of potassium ion transmembrane transporter activity; GO:0065009 regulation of molecular function; GO:0040011 locomotion; GO:1901657 glycosyl compound metabolic process; GO:0072507 divalent inorganic cation homeostasis; GO:0071805 potassium ion transmembrane transport; GO:0016477 cell migration; GO:0016043 cellular component organization; GO:0035725 sodium ion transmembrane transport; GO:0006725 cellular aromatic compound metabolic process; GO:0032411 positive regulation of transporter activity; GO:0060255 regulation of macromolecule metabolic process; GO:0030003 cellular cation homeostasis; GO:1903522 regulation of blood circulation; GO:1903044 protein localization to membrane raft; GO:1903288 positive regulation of potassium ion import; GO:0008016 regulation of heart contraction; GO:0060048 cardiac muscle contraction; GO:0050896 response to stimulus; GO:0055082 cellular chemical homeostasis; GO:1990573 potassium ion import across plasma membrane; GO:0071704 organic substance metabolic process; GO:0090075 relaxation of muscle; GO:0042592 homeostatic process; GO:0006936 muscle contraction; GO:0055080 cation homeostasis; GO:0006812 cation transport; GO:1903169 regulation of calcium ion transmembrane transport; GO:0001666 response to hypoxia; GO:0006886 intracellular protein transport; GO:0008015 blood circulation; GO:0034641 cellular nitrogen compound metabolic process; GO:0060047 heart contraction; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0046034 ATP metabolic process; GO:0055067 monovalent inorganic cation homeostasis; GO:0044861 protein transport into plasma membrane raft; GO:0003008 system process; GO:0035556 intracellular signal transduction; GO:0098660 inorganic ion transmembrane transport; GO:0051049 regulation of transport; GO:0006937 regulation of muscle contraction; GO:0044802 single-organism membrane organization; GO:0006807 nitrogen compound metabolic process; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0051641 cellular localization; GO:0046128 purine ribonucleoside metabolic process; GO:0070727 cellular macromolecule localization; GO:0036376 sodium ion export from cell; GO:0034765 regulation of ion transmembrane transport; GO:0032596 protein transport into membrane raft; GO:0006875 cellular metal ion homeostasis; GO:0009150 purine ribonucleotide metabolic process; GO:1902307 positive regulation of sodium ion transmembrane transport; GO:0086065 cell communication involved in cardiac conduction; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016323 basolateral plasma membrane; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0016324 apical plasma membrane; GO:0098857 membrane microdomain; GO:0030054 cell junction; GO:0044291 cell-cell contact zone; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0005887 integral component of plasma membrane; GO:0005911 cell-cell junction; GO:0005623 cell; GO:0090533 cation-transporting ATPase complex; GO:0014704 intercalated disc; GO:0098533 ATPase dependent transmembrane transport complex; GO:0070062 extracellular exosome; GO:1902494 catalytic complex; GO:0098590 plasma membrane region; GO:0005622 intracellular; GO:0043209 myelin sheath; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0098589 membrane region; GO:1903561 extracellular vesicle; GO:1990351 transporter complex; GO:0045121 membrane raft; GO:0043227 membrane-bounded organelle; GO:0045177 apical part of cell; GO:0031226 intrinsic component of plasma membrane; GO:0005901 caveola; GO:1902495 transmembrane transporter complex; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0044853 plasma membrane raft; GO:1904949 ATPase complex; GO:0005890 sodium:potassium-exchanging ATPase complex; GO:0042383 sarcolemma; GO:0043230 extracellular organelle; ","GO:0042625 ATPase coupled ion transmembrane transporter activity; GO:0008556 potassium-transporting ATPase activity; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0015399 primary active transmembrane transporter activity; GO:0019901 protein kinase binding; GO:0005391 sodium:potassium-exchanging ATPase activity; GO:0022892 substrate-specific transporter activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0015077 monovalent inorganic cation transmembrane transporter activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0003823 antigen binding; GO:0022891 substrate-specific transmembrane transporter activity; GO:0016887 ATPase activity; GO:0046873 metal ion transmembrane transporter activity; GO:0016462 pyrophosphatase activity; GO:0019829 cation-transporting ATPase activity; GO:0003824 catalytic activity; GO:0023023 MHC protein complex binding; GO:0043492 ATPase activity, coupled to movement of substances; GO:0005488 binding; GO:0023026 MHC class II protein complex binding; GO:0008022 protein C-terminus binding; GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; GO:0022890 inorganic cation transmembrane transporter activity; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0015081 sodium ion transmembrane transporter activity; GO:0008047 enzyme activator activity; GO:0005215 transporter activity; GO:0022804 active transmembrane transporter activity; GO:0015075 ion transmembrane transporter activity; GO:0051117 ATPase binding; GO:0022853 active ion transmembrane transporter activity; GO:0044877 macromolecular complex binding; GO:0019900 kinase binding; GO:0017111 nucleoside-triphosphatase activity; GO:0015079 potassium ion transmembrane transporter activity; GO:0001671 ATPase activator activity; GO:0015662 ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism; GO:0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity; GO:0030234 enzyme regulator activity; GO:0042626 ATPase activity, coupled to transmembrane movement of substances; GO:0042623 ATPase activity, coupled; GO:0060590 ATPase regulator activity; GO:0008324 cation transmembrane transporter activity; GO:0019899 enzyme binding; GO:0032403 protein complex binding; GO:0022857 transmembrane transporter activity; ","K01540","ATP1B; sodium/potassium-transporting ATPase subunit beta","hsa04260 Cardiac muscle contraction - Homo sapiens (human); hsa04978 Mineral absorption - Homo sapiens (human); hsa04964 Proximal tubule bicarbonate reclamation - Homo sapiens (human); hsa04973 Carbohydrate digestion and absorption - Homo sapiens (human); hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human); hsa04024 cAMP signaling pathway - Homo sapiens (human); hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human); hsa04976 Bile secretion - Homo sapiens (human); hsa04911 Insulin secretion - Homo sapiens (human); hsa04970 Salivary secretion - Homo sapiens (human); hsa04925 Aldosterone synthesis and secretion - Homo sapiens (human); hsa04960 Aldosterone-regulated sodium reabsorption - Homo sapiens (human); hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human); hsa04972 Pancreatic secretion - Homo sapiens (human); hsa04918 Thyroid hormone synthesis - Homo sapiens (human); hsa04974 Protein digestion and absorption - Homo sapiens (human); hsa04971 Gastric acid secretion - Homo sapiens (human); hsa04961 Endocrine and other factor-regulated calcium reabsorption - Homo sapiens (human); "]
["P05067","Amyloid-beta A4 protein OS=Homo sapiens OX=9606 GN=APP","APP",86.942,6.7212,4,3,3,3,1.172,1.119,1.108,0.824,0.874,0.927,0.772,0.00244,"extracellular\r",{"$cut":{"chars":20552,"head":"GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0021700 developmental maturation; GO:0010941 regulation of cell death; GO:0001967 suckling behavior; GO:0022414 reproductive process; GO:0010608 posttranscriptional regulation of gene expression; GO:0006066 alcohol metabolic process; GO:0009891 positive regulation of biosynthetic process; GO:0043523 regulation of neuron apoptotic process; GO:0098542 defense response to other organism; GO:0046683 response to organophosphorus; GO:1905897 regulation of response to endoplasmic reticulum stress; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0010469 regulation of receptor activity; GO:0001878 response to yeast; GO:0009607 response to biotic stimulus; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0010466 negative regulation of peptidase activity; GO:0008152 metabolic process; GO:0065003 macromolecular complex assembly; GO:0044093 positive regulation of molecular function; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0055065 metal ion homeostasis; GO:0019732 antifungal humoral response; GO:0090068 positive regulation of cell cycle process; GO:1905898 positive regulation of response to endoplasmic reticulum stress; GO:0006396 RNA processing; GO:0052548 regulation of endopeptidase activity; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0006878 cellular copper ion homeostasis; GO:0040014 regulation of multicellular organism growth; GO:0010950 positive regulation of endopeptidase activity; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0008202 steroid metabolic process; GO:0044763 single-organism cellular process; GO:1902751 positive regulation of cell cycle G2/M phase transition; GO:0043086 negative regulation of catalytic activity; GO:0006935 chemotaxis; GO:0051124 synaptic growth at neuromuscular junction; GO:0006874 cellular calcium ion homeostasis; GO:0051704 multi-organism process; GO:0006810 transport; GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0010243 response to organonitrogen compound; GO:0051591 response to cAMP; GO:0045931 positive regulation of mitotic cell cycle; GO:0080135 regulation of cellular response to stress; GO:0007612 learning; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:1901698 response to nitrogen compound; GO:0044260 cellular macromolecule metabolic process; GO:0045665 negative regulation of neuron differentiation; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0010721 negative regulation of cell development; GO:0048609 multicellular organismal reproductive process; GO:0016071 mRNA metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0000003 reproduction; GO:0016310 phosphorylation; GO:0044707 single-multicellular organism process; GO:2001056 positive regulation of cysteine-type endopeptidase activity; GO:1901700 response to oxygen-containing compound; GO:0002576 platelet degranulation; GO:0048519 negative regulation of biological process; GO:1901989 positive regulation of cell cycle phase transition; GO:0030705 cytoskeleton-dependent intracellular transport; GO:0048669 collateral sprouting in absence of injury; GO:0045892 negative regulation of transcription, DNA-templated; GO:0009653 anatomical structure morphogenesis; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0051345 positive regulation of hydrolase activity; GO:0043062 extracellular structure organization; GO:0009889 regulation of biosynthetic process; GO:1902580 single-organism cellular localization; GO:1902680 positive regulation of RNA biosynthetic process; GO:0007631 feeding behavior; GO:0030534 adult behavior; GO:0048878 chemical homeostasis; GO:1990089 response to nerve growth factor; GO:0007617 mating behavior; GO:0045861 negative regula"}},"GO:0030425 dendrite; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0051233 spindle midzone; GO:0031090 organelle membrane; GO:0098857 membrane microdomain; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0032588 trans-Golgi network membrane; GO:0005887 integral component of plasma membrane; GO:0098858 actin-based cell projection; GO:0005623 cell; GO:0043197 dendritic spine; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0098589 membrane region; GO:0030027 lamellipodium; GO:0098791 Golgi subcompartment; GO:0030175 filopodium; GO:0043005 neuron projection; GO:0044306 neuron projection terminus; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0045177 apical part of cell; GO:0043233 organelle lumen; GO:0005929 cilium; GO:0031252 cell leading edge; GO:0031226 intrinsic component of plasma membrane; GO:0042995 cell projection; GO:0005791 rough endoplasmic reticulum; GO:0044430 cytoskeletal part; GO:0031967 organelle envelope; GO:0043235 receptor complex; GO:0044440 endosomal part; GO:0030427 site of polarized growth; GO:0030135 coated vesicle; GO:0005576 extracellular region; GO:0033267 axon part; GO:0031904 endosome lumen; GO:0005886 plasma membrane; GO:0030424 axon; GO:0043231 intracellular membrane-bounded organelle; GO:0098794 postsynapse; GO:0031975 envelope; GO:0043195 terminal bouton; GO:0005905 clathrin-coated pit; GO:0030133 transport vesicle; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0034774 secretory granule lumen; GO:0005790 smooth endoplasmic reticulum; GO:0005615 extracellular space; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0030426 growth cone; GO:0005911 cell-cell junction; GO:0097386 glial cell projection; GO:0043679 axon terminus; GO:0005641 nuclear envelope lumen; GO:0005856 cytoskeleton; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0044309 neuron spine; GO:0070013 intracellular organelle lumen; GO:0031970 organelle envelope lumen; GO:0044441 ciliary part; GO:0015630 microtubule cytoskeleton; GO:0044304 main axon; GO:0098793 presynapse; GO:0044425 membrane part; GO:0044464 cell part; GO:1990761 growth cone lamellipodium; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0044431 Golgi apparatus part; GO:1990812 growth cone filopodium; GO:0005768 endosome; GO:0030141 secretory granule; GO:0045121 membrane raft; GO:0035253 ciliary rootlet; GO:0044456 synapse part; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005635 nuclear envelope; GO:0031594 neuromuscular junction; GO:0044446 intracellular organelle part; GO:0005796 Golgi lumen; GO:0000139 Golgi membrane; GO:0030134 ER to Golgi transport vesicle; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0005819 spindle; GO:0016021 integral component of membrane; GO:0097449 astrocyte projection; GO:0045202 synapse; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0060205 cytoplasmic vesicle lumen; GO:0005802 trans-Golgi network; GO:0043198 dendritic shaft; GO:0031093 platelet alpha granule lumen; GO:0009986 cell surface; GO:0031091 platelet alpha granule; GO:0005794 Golgi apparatus; GO:0090723 growth cone part; GO:0044444 cytoplasmic part; GO:0031984 organelle subcompartment; GO:0044428 nuclear part; ","GO:0005102 receptor binding; GO:0046983 protein dimerization activity; GO:0061134 peptidase regulator activity; GO:0033130 acetylcholine receptor binding; GO:0016504 peptidase activator activity; GO:0005515 protein binding; GO:0008201 heparin binding; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0042802 identical protein binding; GO:0005488 binding; GO:0030414 peptidase inhibitor activity; GO:0043169 cation binding; GO:0043168 anion binding; GO:0061135 endopeptidase regulator activity; GO:0005539 glycosaminoglycan binding; GO:0008047 enzyme activator activity; GO:0003677 DNA binding; GO:0043167 ion binding; GO:0070851 growth factor receptor binding; GO:0004866 endopeptidase inhibitor activity; GO:1901681 sulfur compound binding; GO:0051425 PTB domain binding; GO:0004867 serine-type endopeptidase inhibitor activity; GO:0097367 carbohydrate derivative binding; GO:0030234 enzyme regulator activity; GO:0046914 transition metal ion binding; GO:0042803 protein homodimerization activity; GO:0003676 nucleic acid binding; GO:0046872 metal ion binding; GO:0019904 protein domain specific binding; GO:0019899 enzyme binding; ","K04520","APP; amyloid beta A4 protein","hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04726 Serotonergic synapse - Homo sapiens (human); ","IPR024329; IPR008154; IPR019543; IPR011178; IPR013803; IPR015849; IPR002223; ","\"Amyloidogenic glycoprotein, E2 domain; Amyloidogenic glycoprotein, extracellular; Beta-amyloid precursor protein C-terminal; Amyloidogenic glycoprotein, copper-binding; Amyloidogenic glycoprotein, amyloid-beta peptide; Amyloidogenic glycoprotein, heparin-binding; Pancreatic trypsin inhibitor Kunitz domain; \"\r"]
["P05089","Arginase-1 OS=Homo sapiens OX=9606 GN=ARG1","ARG1",34.735,38.393,33.5,9,14,9,0.751,0.82,0.669,1.28,1.181,1.217,1.642,1.42E-3,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0048732 gland development; GO:0045321 leukocyte activation; GO:0022414 reproductive process; GO:0030323 respiratory tube development; GO:0071384 cellular response to corticosteroid stimulus; GO:0071345 cellular response to cytokine stimulus; GO:0044237 cellular metabolic process; GO:0033189 response to vitamin A; GO:0009607 response to biotic stimulus; GO:0071941 nitrogen cycle metabolic process; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0065003 macromolecular complex assembly; GO:0050678 regulation of epithelial cell proliferation; GO:0009635 response to herbicide; GO:0032879 regulation of localization; GO:0071549 cellular response to dexamethasone stimulus; GO:0044706 multi-multicellular organism process; GO:0044702 single organism reproductive process; GO:0019547 arginine catabolic process to ornithine; GO:0048545 response to steroid hormone; GO:0009719 response to endogenous stimulus; GO:0070848 response to growth factor; GO:0051597 response to methylmercury; GO:0043170 macromolecule metabolic process; GO:0000050 urea cycle; GO:1901652 response to peptide; GO:0044259 multicellular organismal macromolecule metabolic process; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0044281 small molecule metabolic process; GO:0000302 response to reactive oxygen species; GO:0044763 single-organism cellular process; GO:0006525 arginine metabolic process; GO:0043269 regulation of ion transport; GO:0071559 response to transforming growth factor beta; GO:0001938 positive regulation of endothelial cell proliferation; GO:0071353 cellular response to interleukin-4; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0071396 cellular response to lipid; GO:0006810 transport; GO:0046395 carboxylic acid catabolic process; GO:1901575 organic substance catabolic process; GO:0048513 animal organ development; GO:0010243 response to organonitrogen compound; GO:0044710 single-organism metabolic process; GO:1901698 response to nitrogen compound; GO:0009887 animal organ morphogenesis; GO:0009063 cellular amino acid catabolic process; GO:0048609 multicellular organismal reproductive process; GO:0043436 oxoacid metabolic process; GO:0050794 regulation of cellular process; GO:0000003 reproduction; GO:0033554 cellular response to stress; GO:0044707 single-multicellular organism process; GO:0060135 maternal process involved in female pregnancy; GO:0002283 neutrophil activation involved in immune response; GO:0042127 regulation of cell proliferation; GO:0051260 protein homooligomerization; GO:1901700 response to oxygen-containing compound; GO:0030879 mammary gland development; GO:0051259 protein oligomerization; GO:0009653 anatomical structure morphogenesis; GO:0042493 response to drug; GO:0007565 female pregnancy; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0010043 response to zinc ion; GO:0060541 respiratory system development; GO:0044248 cellular catabolic process; GO:0061008 hepaticobiliary system development; GO:0060443 mammary gland morphogenesis; GO:0001936 regulation of endothelial cell proliferation; GO:0007275 multicellular organism development; GO:0070670 response to interleukin-4; GO:0006461 protein complex assembly; GO:0009617 response to bacterium; GO:0019627 urea metabolic process; GO:1901655 cellular response to ketone; GO:0071385 cellular response to glucocorticoid stimulus; GO:0006950 response to stress; GO:0044711 single-organism biosynthetic process; GO:0032496 response to lipopolysaccharide; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0071407 cellular response to organic cyclic compound; GO:0010033 response to organic substance; GO:0010269 response to selenium ion; GO:0044238 primary metabolic process; GO:1901605 alpha-amino acid metabolic process; GO:0007584 response to nutrient; GO:0002263 cell activation involved in immune response; GO:1901576 organic substance biosynthetic process; GO:0070207 protein homotrimerization; GO:0001889 liver development; GO:0045055 regulated exocytosis; GO:0051955 regulation of amino acid transport; GO:0048678 response to axon injury; GO:0042542 response to hydrogen peroxide; GO:0016054 organic acid catabolic process; GO:0071219 cellular response to molecule of bacterial origin; GO:0032963 collagen metabolic process; GO:0001775 cell activation; GO:0033762 response to glucagon; GO:0051179 localization; GO:0006955 immune response; GO:0008284 positive regulation of cell proliferation; GO:0006887 exocytosis; GO:1901564 organonitrogen compound metabolic process; GO:0006527 arginine catabolic process; GO:1901606 alpha-amino acid catabolic process; GO:0001101 response to acid chemical; GO:0032890 regulation of organic acid transport; GO:0032964 collagen biosynthetic process; GO:0044070 regulation of anion transport; GO:0044236 multicellular organism metabolic process; GO:0071560 cellular response to transforming growth factor beta stimulus; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0071363 cellular response to growth factor stimulus; GO:0010963 regulation of L-arginine import; GO:0033197 response to vitamin E; GO:0071383 cellular response to steroid hormone stimulus; GO:0051234 establishment of localization; GO:0014075 response to amine; GO:0009611 response to wounding; GO:0006520 cellular amino acid metabolic process; GO:1901653 cellular response to peptide; GO:0022607 cellular component assembly; GO:0006979 response to oxidative stress; GO:0046686 response to cadmium ion; GO:0034599 cellular response to oxidative stress; GO:0010035 response to inorganic substance; GO:0070887 cellular response to chemical stimulus; GO:0033273 response to vitamin; GO:0002274 myeloid leukocyte activation; GO:0030324 lung development; GO:0032502 developmental process; GO:0043200 response to amino acid; GO:0035295 tube development; GO:0034614 cellular response to reactive oxygen species; GO:0071822 protein complex subunit organization; GO:0034097 response to cytokine; GO:0002237 response to molecule of bacterial origin; GO:0002446 neutrophil mediated immunity; GO:0009636 response to toxic substance; GO:0048522 positive regulation of cellular process; GO:0043603 cellular amide metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0010038 response to metal ion; GO:0051384 response to glucocorticoid; GO:0006591 ornithine metabolic process; GO:0060056 mammary gland involution; GO:0071417 cellular response to organonitrogen compound; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0043434 response to peptide hormone; GO:1901699 cellular response to nitrogen compound; GO:0032940 secretion by cell; GO:0032870 cellular response to hormone stimulus; GO:0007568 aging; GO:0009065 glutamine family amino acid catabolic process; GO:0043299 leukocyte degranulation; GO:0070271 protein complex biogenesis; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:0016043 cellular component organization; GO:0071222 cellular response to lipopolysaccharide; GO:0002252 immune effector process; GO:0071310 cellular response to organic substance; GO:0043207 response to external biotic stimulus; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0071704 organic substance metabolic process; GO:0070301 cellular response to hydrogen peroxide; GO:0009991 response to extracellular stimulus; GO:0033993 response to lipid; GO:0071377 cellular response to glucagon stimulus; GO:0010958 regulation of amino acid import; GO:0051952 regulation of amine transport; GO:0071216 cellular response to biotic stimulus; GO:0071375 cellular response to peptide hormone stimulus; GO:0031960 response to corticosteroid; GO:0010042 response to manganese ion; GO:0034641 cellular nitrogen compound metabolic process; GO:0036230 granulocyte activation; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0048771 tissue remodeling; GO:0009064 glutamine family amino acid metabolic process; GO:0070206 protein trimerization; GO:0051049 regulation of transport; GO:0044712 single-organism catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044282 small molecule catabolic process; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0071548 response to dexamethasone; GO:0002366 leukocyte activation involved in immune response; GO:0032504 multicellular organism reproduction; GO:0042119 neutrophil activation; GO:1901701 cellular response to oxygen-containing compound; GO:1901565 organonitrogen compound catabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0044767 single-organism developmental process; GO:0071495 cellular response to endogenous stimulus; GO:0044703 multi-organism reproductive process; GO:0019752 carboxylic acid metabolic process; GO:0043604 amide biosynthetic process; GO:0031667 response to nutrient levels; GO:0009725 response to hormone; GO:0009056 catabolic process; GO:0022612 gland morphogenesis; GO:0071840 cellular component organization or biogenesis; GO:0050679 positive regulation of epithelial cell proliferation; GO:0065007 biological regulation; GO:1901654 response to ketone; ","GO:0016020 membrane; GO:0034774 secretory granule lumen; GO:0019867 outer membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0043025 neuronal cell body; GO:0044424 intracellular part; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0005740 mitochondrial envelope; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0031968 organelle outer membrane; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0042995 cell projection; GO:0044429 mitochondrial part; GO:0098588 bounding membrane of organelle; GO:0005741 mitochondrial outer membrane; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0042582 azurophil granule; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0036477 somatodendritic compartment; GO:0060205 cytoplasmic vesicle lumen; GO:0035580 specific granule lumen; GO:0005766 primary lysosome; GO:0042581 specific granule; GO:0031975 envelope; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0044297 cell body; GO:0031966 mitochondrial membrane; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0046914 transition metal ion binding; GO:0004053 arginase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0016787 hydrolase activity; GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; GO:0030145 manganese ion binding; ","K01476","E3.5.3.1; arginase [EC:3.5.3.1]","hsa00220 Arginine biosynthesis - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa01230 Biosynthesis of amino acids - Homo sapiens (human); hsa05146 Amoebiasis - Homo sapiens (human); hsa00330 Arginine and proline metabolism - Homo sapiens (human); ","IPR023696; ","Ureohydrolase domain; \r"]
["P05090","Apolipoprotein D OS=Homo sapiens OX=9606 GN=APOD","APOD",21.275,37.63,26.5,5,14,5,0.974,0.996,1.064,1.014,0.984,0.991,0.985,0.637,"extracellular\r","GO:2000405 negative regulation of T cell migration; GO:1903533 regulation of protein targeting; GO:0007420 brain development; GO:0090317 negative regulation of intracellular protein transport; GO:0019216 regulation of lipid metabolic process; GO:0031347 regulation of defense response; GO:0008285 negative regulation of cell proliferation; GO:0006006 glucose metabolic process; GO:1900015 regulation of cytokine production involved in inflammatory response; GO:0001525 angiogenesis; GO:0008152 metabolic process; GO:0032879 regulation of localization; GO:0032102 negative regulation of response to external stimulus; GO:0032387 negative regulation of intracellular transport; GO:1900181 negative regulation of protein localization to nucleus; GO:0046823 negative regulation of nucleocytoplasmic transport; GO:0044765 single-organism transport; GO:0051051 negative regulation of transport; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0006869 lipid transport; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0000302 response to reactive oxygen species; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway; GO:1903392 negative regulation of adherens junction organization; GO:1901888 regulation of cell junction assembly; GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway; GO:0031323 regulation of cellular metabolic process; GO:0005975 carbohydrate metabolic process; GO:2000146 negative regulation of cell motility; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:0034443 negative regulation of lipoprotein oxidation; GO:0048513 animal organ development; GO:0071638 negative regulation of monocyte chemotactic protein-1 production; GO:0044710 single-organism metabolic process; GO:0007417 central nervous system development; GO:0048583 regulation of response to stimulus; GO:2000098 negative regulation of smooth muscle cell-matrix adhesion; GO:0051223 regulation of protein transport; GO:0002682 regulation of immune system process; GO:0002685 regulation of leukocyte migration; GO:0072359 circulatory system development; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0001952 regulation of cell-matrix adhesion; GO:0044707 single-multicellular organism process; GO:0007162 negative regulation of cell adhesion; GO:0042127 regulation of cell proliferation; GO:0050728 negative regulation of inflammatory response; GO:1901889 negative regulation of cell junction assembly; GO:1901700 response to oxygen-containing compound; GO:0080134 regulation of response to stress; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0051239 regulation of multicellular organismal process; GO:0060341 regulation of cellular localization; GO:0009653 anatomical structure morphogenesis; GO:0042493 response to drug; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:1902578 single-organism localization; GO:2000145 regulation of cell motility; GO:0050748 negative regulation of lipoprotein metabolic process; GO:0060588 negative regulation of lipoprotein lipid oxidation; GO:0007275 multicellular organism development; GO:0032880 regulation of protein localization; GO:0001953 negative regulation of cell-matrix adhesion; GO:0009966 regulation of signal transduction; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0050746 regulation of lipoprotein metabolic process; GO:0006950 response to stress; GO:0051270 regulation of cellular component movement; GO:0051224 negative regulation of protein transport; GO:0048731 system development; GO:0071702 organic substance transport; GO:0010876 lipid localization; GO:0032101 regulation of response to external stimulus; GO:0072358 cardiovascular system development; GO:0030334 regulation of cell migration; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0030155 regulation of cell adhesion; GO:0030182 neuron differentiation; GO:0048678 response to axon injury; GO:0046822 regulation of nucleocytoplasmic transport; GO:0030336 negative regulation of cell migration; GO:0071637 regulation of monocyte chemotactic protein-1 production; GO:0010810 regulation of cell-substrate adhesion; GO:0048589 developmental growth; GO:0051179 localization; GO:0040007 growth; GO:1903827 regulation of cellular protein localization; GO:0019318 hexose metabolic process; GO:1903391 regulation of adherens junction organization; GO:0009968 negative regulation of signal transduction; GO:0001568 blood vessel development; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0051129 negative regulation of cellular component organization; GO:0023051 regulation of signaling; GO:0022008 neurogenesis; GO:0090109 regulation of cell-substrate junction assembly; GO:0044699 single-organism process; GO:0051241 negative regulation of multicellular organismal process; GO:0001818 negative regulation of cytokine production; GO:0034442 regulation of lipoprotein oxidation; GO:0042308 negative regulation of protein import into nucleus; GO:0051234 establishment of localization; GO:0040013 negative regulation of locomotion; GO:0009611 response to wounding; GO:0042306 regulation of protein import into nucleus; GO:0010646 regulation of cell communication; GO:1900016 negative regulation of cytokine production involved in inflammatory response; GO:0032642 regulation of chemokine production; GO:2000404 regulation of T cell migration; GO:0006979 response to oxidative stress; GO:0060322 head development; GO:0048514 blood vessel morphogenesis; GO:0033036 macromolecule localization; GO:0006629 lipid metabolic process; GO:0032502 developmental process; GO:0045833 negative regulation of lipid metabolic process; GO:1903828 negative regulation of cellular protein localization; GO:0009888 tissue development; GO:0042246 tissue regeneration; GO:0001944 vasculature development; GO:0032386 regulation of intracellular transport; GO:0031102 neuron projection regeneration; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002683 negative regulation of immune system process; GO:0044723 single-organism carbohydrate metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0030030 cell projection organization; GO:0051895 negative regulation of focal adhesion assembly; GO:0032682 negative regulation of chemokine production; GO:0007568 aging; GO:1900180 regulation of protein localization to nucleus; GO:0019222 regulation of metabolic process; GO:0010812 negative regulation of cell-substrate adhesion; GO:0048856 anatomical structure development; GO:0051271 negative regulation of cellular component movement; GO:0002686 negative regulation of leukocyte migration; GO:0016043 cellular component organization; GO:0048660 regulation of smooth muscle cell proliferation; GO:0060255 regulation of macromolecule metabolic process; GO:0051893 regulation of focal adhesion assembly; GO:0044087 regulation of cellular component biogenesis; GO:1904589 regulation of protein import; GO:0031324 negative regulation of cellular metabolic process; GO:1904590 negative regulation of protein import; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0070201 regulation of establishment of protein localization; GO:0071704 organic substance metabolic process; GO:0060587 regulation of lipoprotein lipid oxidation; GO:0031103 axon regeneration; GO:0030154 cell differentiation; GO:0005996 monosaccharide metabolic process; GO:0009987 cellular process; GO:0033157 regulation of intracellular protein transport; GO:2000402 negative regulation of lymphocyte migration; GO:2000097 regulation of smooth muscle cell-matrix adhesion; GO:0031348 negative regulation of defense response; GO:0051049 regulation of transport; GO:0048585 negative regulation of response to stimulus; GO:0031175 neuron projection development; GO:0048662 negative regulation of smooth muscle cell proliferation; GO:0061564 axon development; GO:0042060 wound healing; GO:2000401 regulation of lymphocyte migration; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0050727 regulation of inflammatory response; GO:0001817 regulation of cytokine production; GO:0051248 negative regulation of protein metabolic process; GO:0014012 peripheral nervous system axon regeneration; GO:1904950 negative regulation of establishment of protein localization; GO:0051128 regulation of cellular component organization; GO:0031099 regeneration; GO:0040012 regulation of locomotion; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0030425 dendrite; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0043025 neuronal cell body; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0043005 neuron projection; GO:0044445 cytosolic part; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0022626 cytosolic ribosome; GO:0043229 intracellular organelle; GO:0005840 ribosome; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0036477 somatodendritic compartment; GO:0044297 cell body; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:0015485 cholesterol binding; GO:0032934 sterol binding; GO:0043178 alcohol binding; GO:0005488 binding; GO:0005319 lipid transporter activity; GO:0008289 lipid binding; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0005496 steroid binding; GO:0036094 small molecule binding; GO:0005215 transporter activity; ","K03098",null,null,"IPR012674; IPR000566; IPR011038; ","Calycin; Lipocalin/cytosolic fatty-acid binding domain; Calycin-like; \r"]
["P05091","Aldehyde dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH2","ALDH2",56.381,259.17,48.4,20,42,16,0.814,0.785,0.792,1.212,1.216,1.177,1.508,1.54e-05,"mitochondria\r","GO:0006069 ethanol oxidation; GO:1901615 organic hydroxy compound metabolic process; GO:0044712 single-organism catabolic process; GO:0006066 alcohol metabolic process; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0034310 primary alcohol catabolic process; GO:0044699 single-organism process; GO:0044282 small molecule catabolic process; GO:0046164 alcohol catabolic process; GO:0005975 carbohydrate metabolic process; GO:0044238 primary metabolic process; GO:0006068 ethanol catabolic process; GO:0071704 organic substance metabolic process; GO:1901575 organic substance catabolic process; GO:0008152 metabolic process; GO:1901616 organic hydroxy compound catabolic process; GO:0044710 single-organism metabolic process; GO:0006067 ethanol metabolic process; GO:0034308 primary alcohol metabolic process; GO:0009056 catabolic process; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0009055 electron carrier activity; GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; GO:0003824 catalytic activity; GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity; GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors; GO:0016491 oxidoreductase activity; GO:0004029 aldehyde dehydrogenase (NAD) activity; ","K00128","ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]","hsa00280 Valine, leucine and isoleucine degradation - Homo sapiens (human); hsa00310 Lysine degradation - Homo sapiens (human); hsa00053 Ascorbate and aldarate metabolism - Homo sapiens (human); hsa00620 Pyruvate metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00561 Glycerolipid metabolism - Homo sapiens (human); hsa00330 Arginine and proline metabolism - Homo sapiens (human); hsa00340 Histidine metabolism - Homo sapiens (human); hsa00071 Fatty acid degradation - Homo sapiens (human); hsa00410 beta-Alanine metabolism - Homo sapiens (human); hsa00380 Tryptophan metabolism - Homo sapiens (human); hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human); ","IPR016161; IPR015590; IPR016162; IPR016163; ","\"Aldehyde/histidinol dehydrogenase; Aldehyde dehydrogenase domain; Aldehyde dehydrogenase N-terminal domain; Aldehyde dehydrogenase, C-terminal; \"\r"]
["P05106","Integrin beta-3 OS=Homo sapiens OX=9606 GN=ITGB3","ITGB3",87.057,33.026,10,7,10,7,0.979,0.886,0.824,1.089,1.129,1.059,1.219,0.0199,"plasma membrane\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0044409 entry into host; GO:0030335 positive regulation of cell migration; GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0060055 angiogenesis involved in wound healing; GO:0007166 cell surface receptor signaling pathway; GO:0032989 cellular component morphogenesis; GO:0010594 regulation of endothelial cell migration; GO:0009605 response to external stimulus; GO:0022610 biological adhesion; GO:0034446 substrate adhesion-dependent cell spreading; GO:0001525 angiogenesis; GO:0051240 positive regulation of multicellular organismal process; GO:0050678 regulation of epithelial cell proliferation; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0007160 cell-matrix adhesion; GO:0007155 cell adhesion; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0051347 positive regulation of transferase activity; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0009790 embryo development; GO:0044419 interspecies interaction between organisms; GO:0048598 embryonic morphogenesis; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0046718 viral entry into host cell; GO:0051051 negative regulation of transport; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0051174 regulation of phosphorus metabolic process; GO:0010632 regulation of epithelial cell migration; GO:0080090 regulation of primary metabolic process; GO:0030168 platelet activation; GO:0016049 cell growth; GO:0001707 mesoderm formation; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0090287 regulation of cellular response to growth factor stimulus; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0051272 positive regulation of cellular component movement; GO:0048870 cell motility; GO:0031323 regulation of cellular metabolic process; GO:0006935 chemotaxis; GO:0001938 positive regulation of endothelial cell proliferation; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0007498 mesoderm development; GO:0006810 transport; GO:0000902 cell morphogenesis; GO:0050900 leukocyte migration; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0098602 single organism cell adhesion; GO:0010604 positive regulation of macromolecule metabolic process; GO:0042330 taxis; GO:0010871 negative regulation of receptor biosynthetic process; GO:0050817 coagulation; GO:0048010 vascular endothelial growth factor receptor signaling pathway; GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation; GO:0050794 regulation of cellular process; GO:0072359 circulatory system development; GO:0044707 single-multicellular organism process; GO:0042127 regulation of cell proliferation; GO:0031399 regulation of protein modification process; GO:0051806 entry into cell of other organism involved in symbiotic interaction; GO:0002576 platelet degranulation; GO:0045714 regulation of low-density lipoprotein particle receptor biosynthetic process; GO:2000147 positive regulation of cell motility; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0032844 regulation of homeostatic process; GO:0046850 regulation of bone remodeling; GO:0034109 homotypic cell-cell adhesion; GO:0051239 regulation of multicellular organismal process; GO:0009653 anatomical structure morphogenesis; GO:0032147 activation of protein kinase activity; GO:1902578 single-organism localization; GO:0009889 regulation of biosynthetic process; GO:2000145 regulation of cell motility; GO:0043062 extracellular structure organization; GO:0051338 regulation of transferase activity; GO:0038027 apolipoprotein A-I-mediated signaling pathway; GO:0050748 negative regulation of lipoprotein metabolic process; GO:0001936 regulation of endothelial cell proliferation; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0050746 regulation of lipoprotein metabolic process; GO:0006950 response to stress; GO:0050919 negative chemotaxis; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0030334 regulation of cell migration; GO:0002376 immune system process; GO:0072358 cardiovascular system development; GO:0009892 negative regulation of metabolic process; GO:0009890 negative regulation of biosynthetic process; GO:0045055 regulated exocytosis; GO:0051247 positive regulation of protein metabolic process; GO:0010883 regulation of lipid storage; GO:0031325 positive regulation of cellular metabolic process; GO:0006928 movement of cell or subcellular component; GO:0001775 cell activation; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0040007 growth; GO:0006887 exocytosis; GO:0008284 positive regulation of cell proliferation; GO:0051093 negative regulation of developmental process; GO:0051674 localization of cell; GO:0001568 blood vessel development; GO:0040017 positive regulation of locomotion; GO:0033627 cell adhesion mediated by integrin; GO:0023051 regulation of signaling; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0034103 regulation of tissue remodeling; GO:0044764 multi-organism cellular process; GO:0034113 heterotypic cell-cell adhesion; GO:0051234 establishment of localization; GO:0009611 response to wounding; GO:0048729 tissue morphogenesis; GO:0016337 single organismal cell-cell adhesion; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0022607 cellular component assembly; GO:0048514 blood vessel morphogenesis; GO:0030198 extracellular matrix organization; GO:0033674 positive regulation of kinase activity; GO:0045596 negative regulation of cell differentiation; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0032502 developmental process; GO:0035295 tube development; GO:0007044 cell-substrate junction assembly; GO:0009888 tissue development; GO:0045937 positive regulation of phosphate metabolic process; GO:0032369 negative regulation of lipid transport; GO:0001704 formation of primary germ layer; GO:0010743 regulation of macrophage derived foam cell differentiation; GO:0098609 cell-cell adhesion; GO:0001944 vasculature development; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0007229 integrin-mediated signaling pathway; GO:0010605 negative regulation of macromolecule metabolic process; GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway; GO:0030260 entry into host cell; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0032940 secretion by cell; GO:0051828 entry into other organism involved in symbiotic interaction; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0010745 negative regulation of macrophage derived foam cell differentiation; GO:0019220 regulation of phosphate metabolic process; GO:0040011 locomotion; GO:0048856 anatomical structure development; GO:0043549 regulation of kinase activity; GO:0070527 platelet aggregation; GO:0045859 regulation of protein kinase activity; GO:0016043 cellular component organization; GO:0034329 cell junction assembly; GO:0016477 cell migration; GO:0010869 regulation of receptor biosynthetic process; GO:0014909 smooth muscle cell migration; GO:0010595 positive regulation of endothelial cell migration; GO:0050730 regulation of peptidyl-tyrosine phosphorylation; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0032368 regulation of lipid transport; GO:0031324 negative regulation of cellular metabolic process; GO:0045124 regulation of bone resorption; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0007599 hemostasis; GO:0000904 cell morphogenesis involved in differentiation; GO:0007369 gastrulation; GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process; GO:0030154 cell differentiation; GO:0023056 positive regulation of signaling; GO:0016032 viral process; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:0010888 negative regulation of lipid storage; GO:0045595 regulation of cell differentiation; GO:0050878 regulation of body fluid levels; GO:0051049 regulation of transport; GO:0001932 regulation of protein phosphorylation; GO:0031401 positive regulation of protein modification process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0010634 positive regulation of epithelial cell migration; GO:0045860 positive regulation of protein kinase activity; GO:0051701 interaction with host; GO:0001934 positive regulation of protein phosphorylation; GO:0048333 mesodermal cell differentiation; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway; GO:0048332 mesoderm morphogenesis; GO:0042060 wound healing; GO:0034330 cell junction organization; GO:0031589 cell-substrate adhesion; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0051248 negative regulation of protein metabolic process; GO:0014812 muscle cell migration; GO:0009967 positive regulation of signal transduction; GO:0040012 regulation of locomotion; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:0050679 positive regulation of epithelial cell proliferation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0032587 ruffle membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0034683 integrin alphav-beta3 complex; GO:0005887 integral component of plasma membrane; GO:0098858 actin-based cell projection; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0098590 plasma membrane region; GO:0031256 leading edge membrane; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0030027 lamellipodium; GO:0030175 filopodium; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0031092 platelet alpha granule membrane; GO:0031252 cell leading edge; GO:0042995 cell projection; GO:0031226 intrinsic component of plasma membrane; GO:0098802 plasma membrane receptor complex; GO:0098797 plasma membrane protein complex; GO:0070161 anchoring junction; GO:0043235 receptor complex; GO:0012506 vesicle membrane; GO:0005576 extracellular region; GO:0031527 filopodium membrane; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0030667 secretory granule membrane; GO:0005902 microvillus; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0071062 alphav-beta3 integrin-vitronectin complex; GO:0098636 protein complex involved in cell adhesion; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0030054 cell junction; GO:0031982 vesicle; GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0048770 pigment granule; GO:0044425 membrane part; GO:0044464 cell part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0005912 adherens junction; GO:0030141 secretory granule; GO:0031528 microvillus membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0042470 melanosome; GO:0044446 intracellular organelle part; GO:0008305 integrin complex; GO:0012505 endomembrane system; GO:0044463 cell projection part; GO:0016021 integral component of membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0031258 lamellipodium membrane; GO:0031253 cell projection membrane; GO:0001726 ruffle; GO:0009986 cell surface; GO:0031091 platelet alpha granule; GO:0044444 cytoplasmic part; ","GO:0038023 signaling receptor activity; GO:0001968 fibronectin binding; GO:0005102 receptor binding; GO:0015026 coreceptor activity; GO:0005126 cytokine receptor binding; GO:0070851 growth factor receptor binding; GO:0005172 vascular endothelial growth factor receptor binding; GO:0005515 protein binding; GO:0003756 protein disulfide isomerase activity; GO:0004871 signal transducer activity; GO:0001618 virus receptor activity; GO:0050840 extracellular matrix binding; GO:0002020 protease binding; GO:0050839 cell adhesion molecule binding; GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds; GO:0005161 platelet-derived growth factor receptor binding; GO:0060089 molecular transducer activity; GO:0016853 isomerase activity; GO:0042802 identical protein binding; GO:0004872 receptor activity; GO:0003824 catalytic activity; GO:0043184 vascular endothelial growth factor receptor 2 binding; GO:0005488 binding; GO:0016860 intramolecular oxidoreductase activity; GO:0019899 enzyme binding; ","K06493","ITGB3; integrin beta 3","hsa04015 Rap1 signaling pathway - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa04640 Hematopoietic cell lineage - Homo sapiens (human); hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa05206 MicroRNAs in cancer - Homo sapiens (human); hsa04512 ECM-receptor interaction - Homo sapiens (human); hsa04380 Osteoclast differentiation - Homo sapiens (human); hsa05414 Dilated cardiomyopathy (DCM) - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa04611 Platelet activation - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); hsa05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human); hsa05410 Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human); ","IPR033760; IPR002369; IPR016201; IPR012896; IPR032695; IPR013111; IPR014836; IPR002035; ","\"Integrin beta N-terminal; Integrin beta subunit, VWA domain; PSI domain; Integrin beta subunit, tail; Integrin domain; EGF-like domain, extracellular; Integrin beta subunit, cytoplasmic domain; von Willebrand factor, type A; \"\r"]
["P05107","Integrin beta-2 OS=Homo sapiens OX=9606 GN=ITGB2","ITGB2",84.781,16.203,9,7,8,7,0.834,0.807,0.806,1.166,1.151,1.219,1.445,5.92e-05,"plasma membrane\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0090130 tissue migration; GO:0045321 leukocyte activation; GO:0045428 regulation of nitric oxide biosynthetic process; GO:0007166 cell surface receptor signaling pathway; GO:0009891 positive regulation of biosynthetic process; GO:0031347 regulation of defense response; GO:0044237 cellular metabolic process; GO:0007492 endoderm development; GO:0009605 response to external stimulus; GO:0055098 response to low-density lipoprotein particle; GO:0022610 biological adhesion; GO:0043542 endothelial cell migration; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0008360 regulation of cell shape; GO:0044093 positive regulation of molecular function; GO:0007160 cell-matrix adhesion; GO:1904018 positive regulation of vasculature development; GO:0009719 response to endogenous stimulus; GO:0030101 natural killer cell activation; GO:0007155 cell adhesion; GO:0055094 response to lipoprotein particle; GO:0043170 macromolecule metabolic process; GO:0008104 protein localization; GO:0009790 embryo development; GO:0048598 embryonic morphogenesis; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0002443 leukocyte mediated immunity; GO:0051174 regulation of phosphorus metabolic process; GO:0072657 protein localization to membrane; GO:0002758 innate immune response-activating signal transduction; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0048870 cell motility; GO:0031323 regulation of cellular metabolic process; GO:0006935 chemotaxis; GO:0032501 multicellular organismal process; GO:0050776 regulation of immune response; GO:0006810 transport; GO:1903506 regulation of nucleic acid-templated transcription; GO:0043113 receptor clustering; GO:0051092 positive regulation of NF-kappaB transcription factor activity; GO:0050900 leukocyte migration; GO:0007267 cell-cell signaling; GO:0010631 epithelial cell migration; GO:0051090 regulation of sequence-specific DNA binding transcription factor activity; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:1904407 positive regulation of nitric oxide metabolic process; GO:0098602 single organism cell adhesion; GO:0044260 cellular macromolecule metabolic process; GO:0042330 taxis; GO:0002682 regulation of immune system process; GO:0045765 regulation of angiogenesis; GO:0051094 positive regulation of developmental process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0002283 neutrophil activation involved in immune response; GO:0031399 regulation of protein modification process; GO:0060326 cell chemotaxis; GO:0080134 regulation of response to stress; GO:0090132 epithelium migration; GO:0051239 regulation of multicellular organismal process; GO:0009653 anatomical structure morphogenesis; GO:0097530 granulocyte migration; GO:0031349 positive regulation of defense response; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0009889 regulation of biosynthetic process; GO:0043062 extracellular structure organization; GO:0051171 regulation of nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0006898 receptor-mediated endocytosis; GO:0034613 cellular protein localization; GO:0050778 positive regulation of immune response; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0002253 activation of immune response; GO:0006950 response to stress; GO:0016192 vesicle-mediated transport; GO:0002523 leukocyte migration involved in inflammatory response; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0002263 cell activation involved in immune response; GO:0045055 regulated exocytosis; GO:0045123 cellular extravasation; GO:0031325 positive regulation of cellular metabolic process; GO:0001775 cell activation; GO:0006928 movement of cell or subcellular component; GO:0012501 programmed cell death; GO:0048584 positive regulation of response to stimulus; GO:0006955 immune response; GO:0031328 positive regulation of cellular biosynthetic process; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0006887 exocytosis; GO:0031623 receptor internalization; GO:0051674 localization of cell; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0051668 localization within membrane; GO:0034113 heterotypic cell-cell adhesion; GO:0051234 establishment of localization; GO:0006909 phagocytosis; GO:1990266 neutrophil migration; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0016337 single organismal cell-cell adhesion; GO:0071621 granulocyte chemotaxis; GO:0007154 cell communication; GO:0097529 myeloid leukocyte migration; GO:0045088 regulation of innate immune response; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0006915 apoptotic process; GO:0002221 pattern recognition receptor signaling pathway; GO:0030198 extracellular matrix organization; GO:0033036 macromolecule localization; GO:0045429 positive regulation of nitric oxide biosynthetic process; GO:0070887 cellular response to chemical stimulus; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0009888 tissue development; GO:0043112 receptor metabolic process; GO:0031326 regulation of cellular biosynthetic process; GO:0071402 cellular response to lipoprotein particle stimulus; GO:0001704 formation of primary germ layer; GO:0002446 neutrophil mediated immunity; GO:0098609 cell-cell adhesion; GO:0048522 positive regulation of cellular process; GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity; GO:0002764 immune response-regulating signaling pathway; GO:0007229 integrin-mediated signaling pathway; GO:0023052 signaling; GO:0002444 myeloid leukocyte mediated immunity; GO:0030593 neutrophil chemotaxis; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0042221 response to chemical; GO:0002224 toll-like receptor signaling pathway; GO:0032940 secretion by cell; GO:0007568 aging; GO:0006954 inflammatory response; GO:0001667 ameboidal-type cell migration; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0043299 leukocyte degranulation; GO:0006952 defense response; GO:0019220 regulation of phosphate metabolic process; GO:0040011 locomotion; GO:2000377 regulation of reactive oxygen species metabolic process; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0016477 cell migration; GO:0016043 cellular component organization; GO:0007159 leukocyte cell-cell adhesion; GO:0002218 activation of innate immune response; GO:1903428 positive regulation of reactive oxygen species biosynthetic process; GO:0002252 immune effector process; GO:0050730 regulation of peptidyl-tyrosine phosphorylation; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0071310 cellular response to organic substance; GO:0050896 response to stimulus; GO:0045766 positive regulation of angiogenesis; GO:0071704 organic substance metabolic process; GO:0007369 gastrulation; GO:0030154 cell differentiation; GO:0002757 immune response-activating signal transduction; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0071404 cellular response to low-density lipoprotein particle stimulus; GO:0006355 regulation of transcription, DNA-templated; GO:0045089 positive regulation of innate immune response; GO:0001706 endoderm formation; GO:0035987 endodermal cell differentiation; GO:1903426 regulation of reactive oxygen species biosynthetic process; GO:1901342 regulation of vasculature development; GO:0001932 regulation of protein phosphorylation; GO:0010556 regulation of macromolecule biosynthetic process; GO:0046649 lymphocyte activation; GO:0043312 neutrophil degranulation; GO:0006897 endocytosis; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0034142 toll-like receptor 4 signaling pathway; GO:0002366 leukocyte activation involved in immune response; GO:0070727 cellular macromolecule localization; GO:0042119 neutrophil activation; GO:2000379 positive regulation of reactive oxygen species metabolic process; GO:0030595 leukocyte chemotaxis; GO:0008219 cell death; GO:0031589 cell-substrate adhesion; GO:0051246 regulation of protein metabolic process; GO:0071495 cellular response to endogenous stimulus; GO:0044767 single-organism developmental process; GO:0002684 positive regulation of immune system process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0051128 regulation of cellular component organization; GO:0022604 regulation of cell morphogenesis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0034687 integrin alphaL-beta2 complex; GO:0098636 protein complex involved in cell adhesion; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0070821 tertiary granule membrane; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0035579 specific granule membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0031226 intrinsic component of plasma membrane; GO:0098588 bounding membrane of organelle; GO:0098802 plasma membrane receptor complex; GO:0098797 plasma membrane protein complex; GO:0070820 tertiary granule; GO:0044446 intracellular organelle part; GO:0043235 receptor complex; GO:0012506 vesicle membrane; GO:0008305 integrin complex; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0030667 secretory granule membrane; GO:0044459 plasma membrane part; GO:0101003 ficolin-1-rich granule membrane; GO:0042581 specific granule; GO:0009986 cell surface; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0038023 signaling receptor activity; GO:0046982 protein heterodimerization activity; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0046983 protein dimerization activity; GO:0019901 protein kinase binding; GO:0005515 protein binding; GO:0004888 transmembrane signaling receptor activity; GO:0019900 kinase binding; GO:0004871 signal transducer activity; GO:0050839 cell adhesion molecule binding; GO:0097367 carbohydrate derivative binding; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0005488 binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0001948 glycoprotein binding; GO:0019899 enzyme binding; GO:0032403 protein complex binding; GO:0030369 ICAM-3 receptor activity; GO:0099600 transmembrane receptor activity; ","K06464","ITGB2; integrin beta 2","hsa05144 Malaria - Homo sapiens (human); hsa05152 Tuberculosis - Homo sapiens (human); hsa04015 Rap1 signaling pathway - Homo sapiens (human); hsa05150 Staphylococcus aureus infection - Homo sapiens (human); hsa04650 Natural killer cell mediated cytotoxicity - Homo sapiens (human); hsa05323 Rheumatoid arthritis - Homo sapiens (human); hsa05140 Leishmaniasis - Homo sapiens (human); hsa05134 Legionellosis - Homo sapiens (human); hsa04610 Complement and coagulation cascades - Homo sapiens (human); hsa05166 HTLV-I infection - Homo sapiens (human); hsa04670 Leukocyte transendothelial migration - Homo sapiens (human); hsa04514 Cell adhesion molecules (CAMs) - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa05146 Amoebiasis - Homo sapiens (human); hsa05416 Viral myocarditis - Homo sapiens (human); hsa04390 Hippo signaling pathway - Homo sapiens (human); hsa05133 Pertussis - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); ","IPR032695; IPR033760; IPR002369; IPR016201; IPR012896; IPR002035; IPR014836; ","\"Integrin domain; Integrin beta N-terminal; Integrin beta subunit, VWA domain; PSI domain; Integrin beta subunit, tail; von Willebrand factor, type A; Integrin beta subunit, cytoplasmic domain; \"\r"]
["P05109","Protein S100-A8 OS=Homo sapiens OX=9606 GN=S100A8","S100A8",10.834,46.834,71,13,66,13,0.374,0.374,0.358,1.544,1.512,1.523,4.14,4.6e-08,"mitochondria\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0010941 regulation of cell death; GO:0045321 leukocyte activation; GO:0032270 positive regulation of cellular protein metabolic process; GO:0070486 leukocyte aggregation; GO:0098542 defense response to other organism; GO:0002793 positive regulation of peptide secretion; GO:0031347 regulation of defense response; GO:0006914 autophagy; GO:0044237 cellular metabolic process; GO:0045927 positive regulation of growth; GO:0009607 response to biotic stimulus; GO:0001558 regulation of cell growth; GO:0022610 biological adhesion; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0055065 metal ion homeostasis; GO:0007155 cell adhesion; GO:0002544 chronic inflammatory response; GO:0051493 regulation of cytoskeleton organization; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0052548 regulation of endopeptidase activity; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0009620 response to fungus; GO:0002443 leukocyte mediated immunity; GO:0010950 positive regulation of endopeptidase activity; GO:0002758 innate immune response-activating signal transduction; GO:0030307 positive regulation of cell growth; GO:0050729 positive regulation of inflammatory response; GO:0080090 regulation of primary metabolic process; GO:0019730 antimicrobial humoral response; GO:0044763 single-organism cellular process; GO:0048870 cell motility; GO:0031323 regulation of cellular metabolic process; GO:0006935 chemotaxis; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0046916 cellular transition metal ion homeostasis; GO:0006810 transport; GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0051092 positive regulation of NF-kappaB transcription factor activity; GO:0050900 leukocyte migration; GO:0042063 gliogenesis; GO:0051336 regulation of hydrolase activity; GO:0002526 acute inflammatory response; GO:0051090 regulation of sequence-specific DNA binding transcription factor activity; GO:0050790 regulation of catalytic activity; GO:0018198 peptidyl-cysteine modification; GO:0007417 central nervous system development; GO:0048583 regulation of response to stimulus; GO:0098602 single organism cell adhesion; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:2001244 positive regulation of intrinsic apoptotic signaling pathway; GO:0002682 regulation of immune system process; GO:0042330 taxis; GO:0006464 cellular protein modification process; GO:0010952 positive regulation of peptidase activity; GO:0043068 positive regulation of programmed cell death; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0051047 positive regulation of secretion; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0002283 neutrophil activation involved in immune response; GO:0055076 transition metal ion homeostasis; GO:2001056 positive regulation of cysteine-type endopeptidase activity; GO:0014002 astrocyte development; GO:0043067 regulation of programmed cell death; GO:1901700 response to oxygen-containing compound; GO:0044267 cellular protein metabolic process; GO:0060326 cell chemotaxis; GO:0080134 regulation of response to stress; GO:0097530 granulocyte migration; GO:0031349 positive regulation of defense response; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0051345 positive regulation of hydrolase activity; GO:0010043 response to zinc ion; GO:0009889 regulation of biosynthetic process; GO:0018119 peptidyl-cysteine S-nitrosylation; GO:0051171 regulation of nitrogen compound metabolic process; GO:0044248 cellular catabolic process; GO:0032602 chemokine production; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:0050778 positive regulation of immune response; GO:0017014 protein nitrosylation; GO:0048878 chemical homeostasis; GO:0009617 response to bacterium; GO:0002253 activation of immune response; GO:0090087 regulation of peptide transport; GO:1902531 regulation of intracellular signal transduction; GO:0006950 response to stress; GO:0032496 response to lipopolysaccharide; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0002523 leukocyte migration involved in inflammatory response; GO:0032101 regulation of response to external stimulus; GO:0097305 response to alcohol; GO:0002376 immune system process; GO:0030162 regulation of proteolysis; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0002263 cell activation involved in immune response; GO:0045055 regulated exocytosis; GO:0051247 positive regulation of protein metabolic process; GO:0006882 cellular zinc ion homeostasis; GO:0006873 cellular ion homeostasis; GO:0001816 cytokine production; GO:0031325 positive regulation of cellular metabolic process; GO:0001775 cell activation; GO:0006928 movement of cell or subcellular component; GO:0012501 programmed cell death; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:0006955 immune response; GO:0043412 macromolecule modification; GO:0070488 neutrophil aggregation; GO:0006887 exocytosis; GO:0072503 cellular divalent inorganic cation homeostasis; GO:0051674 localization of cell; GO:0023051 regulation of signaling; GO:0048869 cellular developmental process; GO:1902533 positive regulation of intracellular signal transduction; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0051046 regulation of secretion; GO:0055069 zinc ion homeostasis; GO:0051234 establishment of localization; GO:0009611 response to wounding; GO:1990266 neutrophil migration; GO:2001233 regulation of apoptotic signaling pathway; GO:2001141 regulation of RNA biosynthetic process; GO:0016337 single organismal cell-cell adhesion; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0071621 granulocyte chemotaxis; GO:0045088 regulation of innate immune response; GO:0097529 myeloid leukocyte migration; GO:0009893 positive regulation of metabolic process; GO:0006915 apoptotic process; GO:0032103 positive regulation of response to external stimulus; GO:0002221 pattern recognition receptor signaling pathway; GO:0010035 response to inorganic substance; GO:0070887 cellular response to chemical stimulus; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0050801 ion homeostasis; GO:2000116 regulation of cysteine-type endopeptidase activity; GO:0002237 response to molecule of bacterial origin; GO:0002446 neutrophil mediated immunity; GO:0098609 cell-cell adhesion; GO:0098771 inorganic ion homeostasis; GO:0019725 cellular homeostasis; GO:0048522 positive regulation of cellular process; GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity; GO:0023052 signaling; GO:0002764 immune response-regulating signaling pathway; GO:0002444 myeloid leukocyte mediated immunity; GO:0010038 response to metal ion; GO:0051050 positive regulation of transport; GO:0010942 positive regulation of cell death; GO:0030593 neutrophil chemotaxis; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0002224 toll-like receptor signaling pathway; GO:0032940 secretion by cell; GO:0006954 inflammatory response; GO:0021782 glial cell development; GO:0048708 astrocyte differentiation; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0043299 leukocyte degranulation; GO:0040011 locomotion; GO:0006952 defense response; GO:0036211 protein modification process; GO:0052547 regulation of peptidase activity; GO:0051238 sequestering of metal ion; GO:0072507 divalent inorganic cation homeostasis; GO:0048856 anatomical structure development; GO:0016477 cell migration; GO:0007159 leukocyte cell-cell adhesion; GO:0002218 activation of innate immune response; GO:0040008 regulation of growth; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0030003 cellular cation homeostasis; GO:0045471 response to ethanol; GO:0043065 positive regulation of apoptotic process; GO:0006959 humoral immune response; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0055082 cellular chemical homeostasis; GO:0045087 innate immune response; GO:0048468 cell development; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0033993 response to lipid; GO:0002791 regulation of peptide secretion; GO:0030154 cell differentiation; GO:0045862 positive regulation of proteolysis; GO:0055080 cation homeostasis; GO:0023056 positive regulation of signaling; GO:2001235 positive regulation of apoptotic signaling pathway; GO:0002757 immune response-activating signal transduction; GO:0010647 positive regulation of cell communication; GO:0036230 granulocyte activation; GO:0051235 maintenance of location; GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0009987 cellular process; GO:0045089 positive regulation of innate immune response; GO:0006355 regulation of transcription, DNA-templated; GO:0042742 defense response to bacterium; GO:0051049 regulation of transport; GO:0032119 sequestering of zinc ion; GO:0033043 regulation of organelle organization; GO:0010556 regulation of macromolecule biosynthetic process; GO:0043312 neutrophil degranulation; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0050832 defense response to fungus; GO:0002366 leukocyte activation involved in immune response; GO:0018193 peptidyl-amino acid modification; GO:0010001 glial cell differentiation; GO:0042119 neutrophil activation; GO:0042060 wound healing; GO:0030595 leukocyte chemotaxis; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:2001242 regulation of intrinsic apoptotic signaling pathway; GO:0002684 positive regulation of immune system process; GO:0050727 regulation of inflammatory response; GO:0006875 cellular metal ion homeostasis; GO:0009967 positive regulation of signal transduction; GO:0051128 regulation of cellular component organization; GO:0009056 catabolic process; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0034774 secretory granule lumen; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0045111 intermediate filament cytoskeleton; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0036041 long-chain fatty acid binding; GO:0005102 receptor binding; GO:0050544 arachidonic acid binding; GO:0043167 ion binding; GO:0050543 icosatetraenoic acid binding; GO:0035325 Toll-like receptor binding; GO:0015631 tubulin binding; GO:0043177 organic acid binding; GO:0005515 protein binding; GO:0008270 zinc ion binding; GO:0033293 monocarboxylic acid binding; GO:0008092 cytoskeletal protein binding; GO:0050786 RAGE receptor binding; GO:0031406 carboxylic acid binding; GO:0046914 transition metal ion binding; GO:0008017 microtubule binding; GO:0005488 binding; GO:0008289 lipid binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0043168 anion binding; GO:0005509 calcium ion binding; GO:0005504 fatty acid binding; GO:0050542 icosanoid binding; GO:0035662 Toll-like receptor 4 binding; GO:1901567 fatty acid derivative binding; GO:0036094 small molecule binding; ","K21127","S100A8; protein S100-A8","hsa04657 IL-17 signaling pathway - Homo sapiens (human); ","IPR002048; IPR011992; IPR013787; ","\"EF-hand domain; EF-hand domain pair; S100/CaBP-9k-type, calcium binding, subdomain; \"\r"]
["P05120","Plasminogen activator inhibitor 2 OS=Homo sapiens OX=9606 GN=SERPINB2","SERPINB2",46.596,32.229,18.8,6,7,6,0.992,1.11,1.008,1.019,0.945,0.943,0.935,0.198,"extracellular\r","GO:0050794 regulation of cellular process; GO:0010941 regulation of cell death; GO:0010951 negative regulation of endopeptidase activity; GO:0065008 regulation of biological quality; GO:0043069 negative regulation of programmed cell death; GO:0060255 regulation of macromolecule metabolic process; GO:0043067 regulation of programmed cell death; GO:0030193 regulation of blood coagulation; GO:0051241 negative regulation of multicellular organismal process; GO:0031324 negative regulation of cellular metabolic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0080134 regulation of response to stress; GO:0050896 response to stimulus; GO:0051346 negative regulation of hydrolase activity; GO:0051239 regulation of multicellular organismal process; GO:0009611 response to wounding; GO:1900047 negative regulation of hemostasis; GO:0042730 fibrinolysis; GO:0010466 negative regulation of peptidase activity; GO:0043066 negative regulation of apoptotic process; GO:0032102 negative regulation of response to external stimulus; GO:1900046 regulation of hemostasis; GO:0052548 regulation of endopeptidase activity; GO:0045861 negative regulation of proteolysis; GO:0050878 regulation of body fluid levels; GO:0006950 response to stress; GO:0080090 regulation of primary metabolic process; GO:0032101 regulation of response to external stimulus; GO:0048585 negative regulation of response to stimulus; GO:0030162 regulation of proteolysis; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0009892 negative regulation of metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0061045 negative regulation of wound healing; GO:1903035 negative regulation of response to wounding; GO:0050818 regulation of coagulation; GO:0030195 negative regulation of blood coagulation; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0042060 wound healing; GO:0051336 regulation of hydrolase activity; GO:0061041 regulation of wound healing; GO:0032269 negative regulation of cellular protein metabolic process; GO:0051246 regulation of protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0019222 regulation of metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0052547 regulation of peptidase activity; GO:0060548 negative regulation of cell death; GO:1903034 regulation of response to wounding; GO:0042981 regulation of apoptotic process; GO:0050819 negative regulation of coagulation; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; ","GO:0004867 serine-type endopeptidase inhibitor activity; GO:0030234 enzyme regulator activity; GO:0030414 peptidase inhibitor activity; GO:0061134 peptidase regulator activity; GO:0061135 endopeptidase regulator activity; GO:0098772 molecular function regulator; GO:0004857 enzyme inhibitor activity; GO:0004866 endopeptidase inhibitor activity; ","K19821","SERPINB2; plasminogen activator inhibitor 2","hsa04610 Complement and coagulation cascades - Homo sapiens (human); ","IPR023796; ","Serpin domain; \r"]
["P05141","ADP/ATP translocase 2 OS=Homo sapiens OX=9606 GN=SLC25A5","SLC25A5",32.852,85.885,38.3,13,38,4,0.839,0.819,1.014,1.129,1.149,1.079,1.256,0.0294,"cytoplasm\r","GO:0010941 regulation of cell death; GO:0065008 regulation of biological quality; GO:0009968 negative regulation of signal transduction; GO:0051129 negative regulation of cellular component organization; GO:0006839 mitochondrial transport; GO:0050796 regulation of insulin secretion; GO:0023051 regulation of signaling; GO:0051046 regulation of secretion; GO:0044699 single-organism process; GO:0015868 purine ribonucleotide transport; GO:0044764 multi-organism cellular process; GO:0010821 regulation of mitochondrion organization; GO:0051503 adenine nucleotide transport; GO:0051234 establishment of localization; GO:2001233 regulation of apoptotic signaling pathway; GO:0010646 regulation of cell communication; GO:1901028 regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; GO:0032879 regulation of localization; GO:0015931 nucleobase-containing compound transport; GO:0007005 mitochondrion organization; GO:0090559 regulation of membrane permeability; GO:0044419 interspecies interaction between organisms; GO:0044765 single-organism transport; GO:0051051 negative regulation of transport; GO:0007059 chromosome segregation; GO:0015851 nucleobase transport; GO:0006862 nucleotide transport; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:1903530 regulation of secretion by cell; GO:0051704 multi-organism process; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0015858 nucleoside transport; GO:0006810 transport; GO:1902589 single-organism organelle organization; GO:0010639 negative regulation of organelle organization; GO:0015748 organophosphate ester transport; GO:0050789 regulation of biological process; GO:0046883 regulation of hormone secretion; GO:0048583 regulation of response to stimulus; GO:0010817 regulation of hormone levels; GO:0051223 regulation of protein transport; GO:0060548 negative regulation of cell death; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0015867 ATP transport; GO:0043069 negative regulation of programmed cell death; GO:0042127 regulation of cell proliferation; GO:0007006 mitochondrial membrane organization; GO:0043067 regulation of programmed cell death; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0070201 regulation of establishment of protein localization; GO:0002791 regulation of peptide secretion; GO:0023057 negative regulation of signaling; GO:1902578 single-organism localization; GO:0010648 negative regulation of cell communication; GO:0046902 regulation of mitochondrial membrane permeability; GO:0043066 negative regulation of apoptotic process; GO:0016032 viral process; GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; GO:1901264 carbohydrate derivative transport; GO:0032880 regulation of protein localization; GO:0050708 regulation of protein secretion; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:0090087 regulation of peptide transport; GO:0010823 negative regulation of mitochondrion organization; GO:0051049 regulation of transport; GO:0015865 purine nucleotide transport; GO:0044802 single-organism membrane organization; GO:0033043 regulation of organelle organization; GO:0071702 organic substance transport; GO:0048585 negative regulation of response to stimulus; GO:0048518 positive regulation of biological process; GO:0006820 anion transport; GO:0055085 transmembrane transport; GO:0015711 organic anion transport; GO:0015853 adenine transport; GO:0006996 organelle organization; GO:0006811 ion transport; GO:0061024 membrane organization; GO:0090276 regulation of peptide hormone secretion; GO:0006863 purine nucleobase transport; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0015866 ADP transport; GO:0042981 regulation of apoptotic process; GO:0071705 nitrogen compound transport; GO:0008284 positive regulation of cell proliferation; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005740 mitochondrial envelope; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0043209 myelin sheath; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0019866 organelle inner membrane; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0043233 organelle lumen; GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0031226 intrinsic component of plasma membrane; GO:0044429 mitochondrial part; GO:0042645 mitochondrial nucleoid; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005819 spindle; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0031012 extracellular matrix; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0031975 envelope; GO:0071817 MMXD complex; GO:0043234 protein complex; GO:0031966 mitochondrial membrane; GO:0043230 extracellular organelle; GO:0009295 nucleoid; GO:0044444 cytoplasmic part; ","GO:0015216 purine nucleotide transmembrane transporter activity; GO:0005345 purine nucleobase transmembrane transporter activity; GO:0031625 ubiquitin protein ligase binding; GO:0000295 adenine nucleotide transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0005471 ATP:ADP antiporter activity; GO:0005515 protein binding; GO:0015297 antiporter activity; GO:0099516 ion antiporter activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0015205 nucleobase transmembrane transporter activity; GO:0015217 ADP transmembrane transporter activity; GO:0005346 purine ribonucleotide transmembrane transporter activity; GO:0015211 purine nucleoside transmembrane transporter activity; GO:0005488 binding; GO:0005347 ATP transmembrane transporter activity; GO:0005337 nucleoside transmembrane transporter activity; GO:0015605 organophosphate ester transmembrane transporter activity; GO:0005215 transporter activity; GO:0015291 secondary active transmembrane transporter activity; GO:0022804 active transmembrane transporter activity; GO:0003723 RNA binding; GO:1901505 carbohydrate derivative transporter activity; GO:0015207 adenine transmembrane transporter activity; GO:0015075 ion transmembrane transporter activity; GO:0015301 anion:anion antiporter activity; GO:0015932 nucleobase-containing compound transmembrane transporter activity; GO:0015215 nucleotide transmembrane transporter activity; GO:0003676 nucleic acid binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0008514 organic anion transmembrane transporter activity; GO:0019899 enzyme binding; GO:0008509 anion transmembrane transporter activity; GO:0022857 transmembrane transporter activity; ","K05863","SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31","hsa04218 Cellular senescence - Homo sapiens (human); hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human); hsa04217 Necroptosis - Homo sapiens (human); hsa04020 Calcium signaling pathway - Homo sapiens (human); hsa05166 HTLV-I infection - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa05164 Influenza A - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); ","IPR023395; ","Mitochondrial carrier domain; \r"]
["P05154","Plasma serine protease inhibitor OS=Homo sapiens OX=9606 GN=SERPINA5","SERPINA5",45.674,40.29,16.7,6,8,6,1.092,0.994,1.09,0.925,0.874,1.017,0.887,0.088,"extracellular\r","GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0048732 gland development; GO:0022414 reproductive process; GO:0061107 seminal vesicle development; GO:0044699 single-organism process; GO:0051234 establishment of localization; GO:0009611 response to wounding; GO:0010466 negative regulation of peptidase activity; GO:0007342 fusion of sperm to egg plasma membrane; GO:0044702 single organism reproductive process; GO:0033036 macromolecule localization; GO:0044801 single-organism membrane fusion; GO:0044765 single-organism transport; GO:0032502 developmental process; GO:0052548 regulation of endopeptidase activity; GO:0003006 developmental process involved in reproduction; GO:0006869 lipid transport; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0019953 sexual reproduction; GO:0048608 reproductive structure development; GO:0061025 membrane fusion; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0009566 fertilization; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0022412 cellular process involved in reproduction in multicellular organism; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0045026 plasma membrane fusion; GO:0050817 coagulation; GO:0052547 regulation of peptidase activity; GO:0048609 multicellular organismal reproductive process; GO:0048856 anatomical structure development; GO:0050794 regulation of cellular process; GO:0000003 reproduction; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0010951 negative regulation of endopeptidase activity; GO:0060255 regulation of macromolecule metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0051346 negative regulation of hydrolase activity; GO:0007599 hemostasis; GO:1902578 single-organism localization; GO:0007275 multicellular organism development; GO:0061458 reproductive system development; GO:0009987 cellular process; GO:0045861 negative regulation of proteolysis; GO:0050878 regulation of body fluid levels; GO:0048232 male gamete generation; GO:0006950 response to stress; GO:0007283 spermatogenesis; GO:0048731 system development; GO:0044802 single-organism membrane organization; GO:0071702 organic substance transport; GO:0010876 lipid localization; GO:0030162 regulation of proteolysis; GO:0007338 single fertilization; GO:0009892 negative regulation of metabolic process; GO:0007276 gamete generation; GO:0032504 multicellular organism reproduction; GO:0042060 wound healing; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0061024 membrane organization; GO:0044703 multi-organism reproductive process; GO:0051248 negative regulation of protein metabolic process; GO:0051179 localization; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0036029 protein C inhibitor-KLK3 complex; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0097181 protein C inhibitor-coagulation factor V complex; GO:0009897 external side of plasma membrane; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0097182 protein C inhibitor-coagulation factor Xa complex; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0036027 protein C inhibitor-PLAU complex; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0036024 protein C inhibitor-TMPRSS7 complex; GO:0036025 protein C inhibitor-TMPRSS11E complex; GO:0070062 extracellular exosome; GO:0036030 protein C inhibitor-plasma kallikrein complex; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0031094 platelet dense tubular network; GO:0097180 serine protease inhibitor complex; GO:0098552 side of membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0097183 protein C inhibitor-coagulation factor XI complex; GO:0044446 intracellular organelle part; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0002080 acrosomal membrane; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0036026 protein C inhibitor-PLAT complex; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0030667 secretory granule membrane; GO:0044459 plasma membrane part; GO:0001669 acrosomal vesicle; GO:0097179 protease inhibitor complex; GO:0009986 cell surface; GO:0031091 platelet alpha granule; GO:0036028 protein C inhibitor-thrombin complex; GO:0097223 sperm part; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0032190 acrosin binding; GO:0070405 ammonium ion binding; GO:0061134 peptidase regulator activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0004857 enzyme inhibitor activity; GO:0008201 heparin binding; GO:0031210 phosphatidylcholine binding; GO:0050997 quaternary ammonium group binding; GO:0031406 carboxylic acid binding; GO:0005488 binding; GO:0030414 peptidase inhibitor activity; GO:0008289 lipid binding; GO:0043169 cation binding; GO:0061135 endopeptidase regulator activity; GO:0043168 anion binding; GO:0005539 glycosaminoglycan binding; GO:0001972 retinoic acid binding; GO:0043167 ion binding; GO:0005501 retinoid binding; GO:0043177 organic acid binding; GO:0019840 isoprenoid binding; GO:0033293 monocarboxylic acid binding; GO:0004866 endopeptidase inhibitor activity; GO:1901681 sulfur compound binding; GO:0002020 protease binding; GO:0097367 carbohydrate derivative binding; GO:0004867 serine-type endopeptidase inhibitor activity; GO:0030234 enzyme regulator activity; GO:0005543 phospholipid binding; GO:0019899 enzyme binding; GO:0036094 small molecule binding; ","K03913","SERPINA5; protein C inhibitor","hsa04610 Complement and coagulation cascades - Homo sapiens (human); ","IPR023796; ","Serpin domain; \r"]
["P05155","Plasma protease C1 inhibitor OS=Homo sapiens OX=9606 GN=SERPING1","SERPING1",55.154,84.825,21.8,11,26,11,0.932,1.016,0.973,1.042,1.009,1.038,1.058,0.104,"extracellular\r","GO:0016064 immunoglobulin mediated immune response; GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0002698 negative regulation of immune effector process; GO:1903318 negative regulation of protein maturation; GO:0045916 negative regulation of complement activation; GO:0031347 regulation of defense response; GO:0042730 fibrinolysis; GO:0006956 complement activation; GO:0010466 negative regulation of peptidase activity; GO:0008152 metabolic process; GO:0032102 negative regulation of response to external stimulus; GO:0006958 complement activation, classical pathway; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0052548 regulation of endopeptidase activity; GO:0002443 leukocyte mediated immunity; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0048583 regulation of response to stimulus; GO:0002682 regulation of immune system process; GO:1903317 regulation of protein maturation; GO:0050817 coagulation; GO:0003013 circulatory system process; GO:0050794 regulation of cellular process; GO:0030449 regulation of complement activation; GO:0044707 single-multicellular organism process; GO:2000257 regulation of protein activation cascade; GO:0010951 negative regulation of endopeptidase activity; GO:0002920 regulation of humoral immune response; GO:0010955 negative regulation of protein processing; GO:0030193 regulation of blood coagulation; GO:0002576 platelet degranulation; GO:0080134 regulation of response to stress; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0051239 regulation of multicellular organismal process; GO:0019724 B cell mediated immunity; GO:1900047 negative regulation of hemostasis; GO:2000258 negative regulation of protein activation cascade; GO:1902578 single-organism localization; GO:0002449 lymphocyte mediated immunity; GO:0050778 positive regulation of immune response; GO:0002253 activation of immune response; GO:0045861 negative regulation of proteolysis; GO:0006950 response to stress; GO:0016192 vesicle-mediated transport; GO:0032101 regulation of response to external stimulus; GO:0072376 protein activation cascade; GO:0002376 immune system process; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0072378 blood coagulation, fibrin clot formation; GO:0030195 negative regulation of blood coagulation; GO:0045055 regulated exocytosis; GO:0061041 regulation of wound healing; GO:0070613 regulation of protein processing; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0048584 positive regulation of response to stimulus; GO:0006955 immune response; GO:0051179 localization; GO:1903034 regulation of response to wounding; GO:0050819 negative regulation of coagulation; GO:0006887 exocytosis; GO:0044699 single-organism process; GO:0051241 negative regulation of multicellular organismal process; GO:0051234 establishment of localization; GO:0009611 response to wounding; GO:0045088 regulation of innate immune response; GO:0002250 adaptive immune response; GO:1900046 regulation of hemostasis; GO:0050777 negative regulation of immune response; GO:0002697 regulation of immune effector process; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0007597 blood coagulation, intrinsic pathway; GO:0001868 regulation of complement activation, lectin pathway; GO:0010605 negative regulation of macromolecule metabolic process; GO:1903035 negative regulation of response to wounding; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0002683 negative regulation of immune system process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0032940 secretion by cell; GO:0007568 aging; GO:0001869 negative regulation of complement activation, lectin pathway; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0006952 defense response; GO:0052547 regulation of peptidase activity; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0002673 regulation of acute inflammatory response; GO:0006959 humoral immune response; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0002921 negative regulation of humoral immune response; GO:0007599 hemostasis; GO:0051346 negative regulation of hydrolase activity; GO:0045087 innate immune response; GO:0071704 organic substance metabolic process; GO:0008015 blood circulation; GO:0009987 cellular process; GO:0031348 negative regulation of defense response; GO:0003008 system process; GO:0050878 regulation of body fluid levels; GO:0010629 negative regulation of gene expression; GO:0048585 negative regulation of response to stimulus; GO:0061045 negative regulation of wound healing; GO:0048518 positive regulation of biological process; GO:0050818 regulation of coagulation; GO:0045824 negative regulation of innate immune response; GO:0042060 wound healing; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0002684 positive regulation of immune system process; GO:0050727 regulation of inflammatory response; GO:0051248 negative regulation of protein metabolic process; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0043226 organelle; GO:0072562 blood microparticle; GO:0060205 cytoplasmic vesicle lumen; GO:0031093 platelet alpha granule lumen; GO:0031091 platelet alpha granule; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0004867 serine-type endopeptidase inhibitor activity; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0030414 peptidase inhibitor activity; GO:0061134 peptidase regulator activity; GO:0005515 protein binding; GO:0061135 endopeptidase regulator activity; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0004866 endopeptidase inhibitor activity; ","K04001","SERPING1; C1 inhibitor","hsa05133 Pertussis - Homo sapiens (human); hsa04610 Complement and coagulation cascades - Homo sapiens (human); ","IPR023796; ","Serpin domain; \r"]
["P05156","Complement factor I OS=Homo sapiens OX=9606 GN=CFI","CFI",65.75,74.38,25,12,19,12,1.015,1.005,0.966,1.044,1,0.977,1.012,0.665,"extracellular\r","GO:0030449 regulation of complement activation; GO:0016064 immunoglobulin mediated immune response; GO:2000257 regulation of protein activation cascade; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0002920 regulation of humoral immune response; GO:0002673 regulation of acute inflammatory response; GO:0006959 humoral immune response; GO:0080134 regulation of response to stress; GO:0050896 response to stimulus; GO:0031347 regulation of defense response; GO:0045087 innate immune response; GO:0051234 establishment of localization; GO:0071704 organic substance metabolic process; GO:0019724 B cell mediated immunity; GO:0006956 complement activation; GO:0008152 metabolic process; GO:0002250 adaptive immune response; GO:0006958 complement activation, classical pathway; GO:0006508 proteolysis; GO:0006898 receptor-mediated endocytosis; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0002449 lymphocyte mediated immunity; GO:0050778 positive regulation of immune response; GO:0002697 regulation of immune effector process; GO:0010468 regulation of gene expression; GO:0002253 activation of immune response; GO:0002443 leukocyte mediated immunity; GO:0006950 response to stress; GO:0080090 regulation of primary metabolic process; GO:0016192 vesicle-mediated transport; GO:0072376 protein activation cascade; GO:0032101 regulation of response to external stimulus; GO:0002376 immune system process; GO:0030162 regulation of proteolysis; GO:0006897 endocytosis; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0051246 regulation of protein metabolic process; GO:0002684 positive regulation of immune system process; GO:0048583 regulation of response to stimulus; GO:0070613 regulation of protein processing; GO:0050727 regulation of inflammatory response; GO:0019222 regulation of metabolic process; GO:0002682 regulation of immune system process; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:1903317 regulation of protein maturation; GO:0006952 defense response; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:0006955 immune response; GO:0065007 biological regulation; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:0008233 peptidase activity; GO:0043167 ion binding; GO:0008236 serine-type peptidase activity; GO:0038024 cargo receptor activity; GO:0005515 protein binding; GO:0005044 scavenger receptor activity; GO:0016787 hydrolase activity; GO:0004175 endopeptidase activity; GO:0004252 serine-type endopeptidase activity; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0003824 catalytic activity; GO:0017171 serine hydrolase activity; GO:0005488 binding; GO:0046872 metal ion binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0043169 cation binding; ","K01333","CFI; complement factor I [EC:3.4.21.45]","hsa04610 Complement and coagulation cascades - Homo sapiens (human); hsa05150 Staphylococcus aureus infection - Homo sapiens (human); ","IPR009003; IPR001190; IPR017448; IPR002350; IPR003884; IPR001254; ","\"Peptidase S1, PA clan; SRCR domain; SRCR-like domain; Kazal domain; Factor I / membrane attack complex; Serine proteases, trypsin domain; \"\r"]
["P05164","Myeloperoxidase OS=Homo sapiens OX=9606 GN=MPO","MPO",83.868,35.924,16.2,10,13,9,0.603,0.736,0.595,1.306,1.328,1.316,2.042,0.00908,"extracellular\r","GO:0006801 superoxide metabolic process; GO:0010941 regulation of cell death; GO:0045321 leukocyte activation; GO:0098542 defense response to other organism; GO:0044237 cellular metabolic process; GO:0001878 response to yeast; GO:0009607 response to biotic stimulus; GO:0019430 removal of superoxide radicals; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0071825 protein-lipid complex subunit organization; GO:0098869 cellular oxidant detoxification; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0009620 response to fungus; GO:0000302 response to reactive oxygen species; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0044710 single-organism metabolic process; GO:0060548 negative regulation of cell death; GO:0043436 oxoacid metabolic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0033554 cellular response to stress; GO:0002283 neutrophil activation involved in immune response; GO:0044144 modulation of growth of symbiont involved in interaction with host; GO:0009628 response to abiotic stimulus; GO:0043067 regulation of programmed cell death; GO:1901700 response to oxygen-containing compound; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0044146 negative regulation of growth of symbiont involved in interaction with host; GO:0042743 hydrogen peroxide metabolic process; GO:1990748 cellular detoxification; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0002148 hypochlorous acid metabolic process; GO:0044248 cellular catabolic process; GO:0034369 plasma lipoprotein particle remodeling; GO:0042744 hydrogen peroxide catabolic process; GO:0009617 response to bacterium; GO:1903409 reactive oxygen species biosynthetic process; GO:0032094 response to food; GO:0044711 single-organism biosynthetic process; GO:0006950 response to stress; GO:0032496 response to lipopolysaccharide; GO:0016192 vesicle-mediated transport; GO:0043900 regulation of multi-organism process; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0002263 cell activation involved in immune response; GO:1990267 response to transition metal nanoparticle; GO:0045055 regulated exocytosis; GO:0045730 respiratory burst; GO:0044283 small molecule biosynthetic process; GO:0001775 cell activation; GO:0051179 localization; GO:0006955 immune response; GO:0006887 exocytosis; GO:0034367 macromolecular complex remodeling; GO:0000303 response to superoxide; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0051234 establishment of localization; GO:0044126 regulation of growth of symbiont in host; GO:0006979 response to oxidative stress; GO:0034599 cellular response to oxidative stress; GO:0010035 response to inorganic substance; GO:0070887 cellular response to chemical stimulus; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:0071827 plasma lipoprotein particle organization; GO:0045926 negative regulation of growth; GO:0034614 cellular response to reactive oxygen species; GO:0071450 cellular response to oxygen radical; GO:0002237 response to molecule of bacterial origin; GO:0055114 oxidation-reduction process; GO:0009636 response to toxic substance; GO:0002446 neutrophil mediated immunity; GO:0002444 myeloid leukocyte mediated immunity; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0032940 secretion by cell; GO:0007568 aging; GO:0000305 response to oxygen radical; GO:0006952 defense response; GO:0043299 leukocyte degranulation; GO:0006082 organic acid metabolic process; GO:0098754 detoxification; GO:0016043 cellular component organization; GO:0043069 negative regulation of programmed cell death; GO:0040008 regulation of growth; GO:0034374 low-density lipoprotein particle remodeling; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0002252 immune effector process; GO:0043207 response to external biotic stimulus; GO:0002149 hypochlorous acid biosynthetic process; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0071704 organic substance metabolic process; GO:0097006 regulation of plasma lipoprotein particle levels; GO:0009612 response to mechanical stimulus; GO:0009991 response to extracellular stimulus; GO:0033993 response to lipid; GO:0072593 reactive oxygen species metabolic process; GO:0043066 negative regulation of apoptotic process; GO:0044130 negative regulation of growth of symbiont in host; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0071451 cellular response to superoxide; GO:0042742 defense response to bacterium; GO:0043312 neutrophil degranulation; GO:1990268 response to gold nanoparticle; GO:0043933 macromolecular complex subunit organization; GO:0043901 negative regulation of multi-organism process; GO:0002366 leukocyte activation involved in immune response; GO:0050832 defense response to fungus; GO:0042119 neutrophil activation; GO:1901701 cellular response to oxygen-containing compound; GO:0044767 single-organism developmental process; GO:0002679 respiratory burst involved in defense response; GO:0031667 response to nutrient levels; GO:0034368 protein-lipid complex remodeling; GO:0009056 catabolic process; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0042582 azurophil granule; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0043167 ion binding; GO:0016209 antioxidant activity; GO:0003682 chromatin binding; GO:0008201 heparin binding; GO:1901681 sulfur compound binding; GO:0016491 oxidoreductase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0020037 heme binding; GO:0097367 carbohydrate derivative binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0043168 anion binding; GO:0004601 peroxidase activity; GO:0005539 glycosaminoglycan binding; GO:0046906 tetrapyrrole binding; GO:0016684 oxidoreductase activity, acting on peroxide as acceptor; ","K10789","MPO; myeloperoxidase [EC:1.11.2.2]","hsa00983 Drug metabolism - other enzymes - Homo sapiens (human); hsa05221 Acute myeloid leukemia - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human); "]
["P05165","Propionyl-CoA carboxylase alpha chain, mitochondrial OS=Homo sapiens OX=9606 GN=PCCA","PCCA",80.058,35.764,12.2,7,7,7,1.094,1.034,1.036,1.029,0.933,0.935,0.916,0.0753,"mitochondria\r","GO:0006768 biotin metabolic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0006766 vitamin metabolic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009987 cellular process; GO:0006767 water-soluble vitamin metabolic process; GO:0006629 lipid metabolic process; GO:0019626 short-chain fatty acid catabolic process; GO:0006790 sulfur compound metabolic process; GO:0016042 lipid catabolic process; GO:0044712 single-organism catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:0072329 monocarboxylic acid catabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0044282 small molecule catabolic process; GO:0043603 cellular amide metabolic process; GO:0006631 fatty acid metabolic process; GO:0044238 primary metabolic process; GO:0051186 cofactor metabolic process; GO:0046395 carboxylic acid catabolic process; GO:1901575 organic substance catabolic process; GO:0044710 single-organism metabolic process; GO:0016054 organic acid catabolic process; GO:0019752 carboxylic acid metabolic process; GO:0044242 cellular lipid catabolic process; GO:0046459 short-chain fatty acid metabolic process; GO:0006082 organic acid metabolic process; GO:0009056 catabolic process; GO:0009062 fatty acid catabolic process; GO:0043436 oxoacid metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0004658 propionyl-CoA carboxylase activity; GO:1901265 nucleoside phosphate binding; GO:0016885 ligase activity, forming carbon-carbon bonds; GO:0016874 ligase activity; GO:0005515 protein binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0031406 carboxylic acid binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0019842 vitamin binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0043177 organic acid binding; GO:0033218 amide binding; GO:0000166 nucleotide binding; GO:0033293 monocarboxylic acid binding; GO:1901681 sulfur compound binding; GO:0016879 ligase activity, forming carbon-nitrogen bonds; GO:0032549 ribonucleoside binding; GO:0004075 biotin carboxylase activity; GO:0097367 carbohydrate derivative binding; GO:0016421 CoA carboxylase activity; GO:0009374 biotin binding; GO:0046872 metal ion binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019899 enzyme binding; GO:0036094 small molecule binding; ","K01965","PCCA; propionyl-CoA carboxylase alpha chain [EC:6.4.1.3]","hsa00280 Valine, leucine and isoleucine degradation - Homo sapiens (human); hsa00640 Propanoate metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); hsa00630 Glyoxylate and dicarboxylate metabolism - Homo sapiens (human); ","IPR016185; IPR011764; IPR011053; IPR005482; IPR011761; IPR000089; IPR005481; IPR005479; IPR013816; IPR013815; IPR011054; ","\"Pre-ATP-grasp domain; Biotin carboxylation domain; Single hybrid motif; Biotin carboxylase, C-terminal; ATP-grasp fold; Biotin/lipoyl attachment; Biotin carboxylase-like, N-terminal domain; Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain; ATP-grasp fold, subdomain 2; ATP-grasp fold, subdomain 1; Rudiment single hybrid motif; \"\r"]
["P05166","Propionyl-CoA carboxylase beta chain, mitochondrial OS=Homo sapiens OX=9606 GN=PCCB","PCCB",58.215,40.155,15,7,9,7,1.036,0.935,1.196,1,1.05,0.92,0.938,0.497,"mitochondria\r","GO:0006768 biotin metabolic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0006766 vitamin metabolic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009987 cellular process; GO:0006767 water-soluble vitamin metabolic process; GO:0006629 lipid metabolic process; GO:0019626 short-chain fatty acid catabolic process; GO:0006790 sulfur compound metabolic process; GO:0016042 lipid catabolic process; GO:0044712 single-organism catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:0072329 monocarboxylic acid catabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0044282 small molecule catabolic process; GO:0043603 cellular amide metabolic process; GO:0006631 fatty acid metabolic process; GO:0044238 primary metabolic process; GO:0051186 cofactor metabolic process; GO:0046395 carboxylic acid catabolic process; GO:1901575 organic substance catabolic process; GO:0044710 single-organism metabolic process; GO:0016054 organic acid catabolic process; GO:0019752 carboxylic acid metabolic process; GO:0044242 cellular lipid catabolic process; GO:0046459 short-chain fatty acid metabolic process; GO:0006082 organic acid metabolic process; GO:0009056 catabolic process; GO:0009062 fatty acid catabolic process; GO:0043436 oxoacid metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0004658 propionyl-CoA carboxylase activity; GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0016885 ligase activity, forming carbon-carbon bonds; GO:0016874 ligase activity; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016421 CoA carboxylase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K01966","PCCB; propionyl-CoA carboxylase beta chain [EC:6.4.1.3 2.1.3.15]","hsa00280 Valine, leucine and isoleucine degradation - Homo sapiens (human); hsa00640 Propanoate metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); hsa00630 Glyoxylate and dicarboxylate metabolism - Homo sapiens (human); ","IPR011762; IPR000022; IPR029045; IPR011763; ","\"Acetyl-coenzyme A carboxyltransferase, N-terminal; Carboxyl transferase; ClpP/crotonase-like domain; Acetyl-coenzyme A carboxyltransferase, C-terminal; \"\r"]
["P05198","Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1","EIF2S1",36.112,81.463,32.7,12,14,12,0.882,0.854,0.851,1.09,1.123,1.125,1.29,7.82e-05,"cytoplasm\r","GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0006518 peptide metabolic process; GO:0010608 posttranscriptional regulation of gene expression; GO:0034644 cellular response to UV; GO:0043555 regulation of translation in response to stress; GO:0044237 cellular metabolic process; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0035966 response to topologically incorrect protein; GO:0009408 response to heat; GO:0044093 positive regulation of molecular function; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0051099 positive regulation of binding; GO:0051716 cellular response to stimulus; GO:0071214 cellular response to abiotic stimulus; GO:0080090 regulation of primary metabolic process; GO:0034249 negative regulation of cellular amide metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0006810 transport; GO:0071482 cellular response to light stimulus; GO:2000674 regulation of type B pancreatic cell apoptotic process; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0043068 positive regulation of programmed cell death; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016310 phosphorylation; GO:0033554 cellular response to stress; GO:0009267 cellular response to starvation; GO:0034976 response to endoplasmic reticulum stress; GO:0009628 response to abiotic stimulus; GO:0044267 cellular protein metabolic process; GO:0043067 regulation of programmed cell death; GO:0045947 negative regulation of translational initiation; GO:0043558 regulation of translational initiation in response to stress; GO:0017148 negative regulation of translation; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:1990737 response to manganese-induced endoplasmic reticulum stress; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:1904035 regulation of epithelial cell apoptotic process; GO:0006986 response to unfolded protein; GO:0006950 response to stress; GO:0009416 response to light stimulus; GO:0071496 cellular response to external stimulus; GO:0010033 response to organic substance; GO:0006984 ER-nucleus signaling pathway; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0031668 cellular response to extracellular stimulus; GO:0034248 regulation of cellular amide metabolic process; GO:0055085 transmembrane transport; GO:1905097 regulation of guanyl-nucleotide exchange factor activity; GO:0009890 negative regulation of biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0051179 localization; GO:0071248 cellular response to metal ion; GO:0043412 macromolecule modification; GO:0036499 PERK-mediated unfolded protein response; GO:1901564 organonitrogen compound metabolic process; GO:2000676 positive regulation of type B pancreatic cell apoptotic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0030968 endoplasmic reticulum unfolded protein response; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0032057 negative regulation of translational initiation in response to stress; GO:0071287 cellular response to manganese ion; GO:0046777 protein autophosphorylation; GO:0006413 translational initiation; GO:0009314 response to radiation; GO:0010035 response to inorganic substance; GO:0006412 translation; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0043043 peptide biosynthetic process; GO:0051098 regulation of binding; GO:0048522 positive regulation of cellular process; GO:0043603 cellular amide metabolic process; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0010038 response to metal ion; GO:0010942 positive regulation of cell death; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0042221 response to chemical; GO:0034605 cellular response to heat; GO:0007568 aging; GO:0065009 regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0019222 regulation of metabolic process; GO:0071241 cellular response to inorganic substance; GO:0044092 negative regulation of molecular function; GO:0036211 protein modification process; GO:0034198 cellular response to amino acid starvation; GO:0035967 cellular response to topologically incorrect protein; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0043065 positive regulation of apoptotic process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:1901566 organonitrogen compound biosynthetic process; GO:0031669 cellular response to nutrient levels; GO:0071704 organic substance metabolic process; GO:0009991 response to extracellular stimulus; GO:0006468 protein phosphorylation; GO:1901216 positive regulation of neuron death; GO:0009266 response to temperature stimulus; GO:0010042 response to manganese ion; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0071478 cellular response to radiation; GO:0009987 cellular process; GO:0032055 negative regulation of translation in response to stress; GO:1901214 regulation of neuron death; GO:0034620 cellular response to unfolded protein; GO:0010629 negative regulation of gene expression; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:1904037 positive regulation of epithelial cell apoptotic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0009411 response to UV; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0051246 regulation of protein metabolic process; GO:0006417 regulation of translation; GO:0044767 single-organism developmental process; GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity; GO:0006446 regulation of translational initiation; GO:0051248 negative regulation of protein metabolic process; GO:0042594 response to starvation; GO:0010467 gene expression; GO:0031667 response to nutrient levels; GO:0031327 negative regulation of cellular biosynthetic process; GO:0043604 amide biosynthetic process; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005850 eukaryotic translation initiation factor 2 complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044207 translation initiation ternary complex; GO:0097386 glial cell projection; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:0070993 translation preinitiation complex; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005840 ribosome; GO:0010494 cytoplasmic stress granule; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0097451 glial limiting end-foot; GO:0005829 cytosol; GO:0033290 eukaryotic 48S preinitiation complex; GO:0005576 extracellular region; GO:0097449 astrocyte projection; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0097450 astrocyte end-foot; GO:0005634 nucleus; GO:0035770 ribonucleoprotein granule; GO:0043614 multi-eIF complex; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0005844 polysome; ","GO:0043022 ribosome binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0008135 translation factor activity, RNA binding; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0003676 nucleic acid binding; GO:0003743 translation initiation factor activity; GO:0005515 protein binding; GO:0043021 ribonucleoprotein complex binding; ","K03237","EIF2S1; translation initiation factor 2 subunit 1","hsa04210 Apoptosis - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa05168 Herpes simplex infection - Homo sapiens (human); hsa05160 Hepatitis C - Homo sapiens (human); hsa03013 RNA transport - Homo sapiens (human); hsa05162 Measles - Homo sapiens (human); hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); hsa04140 Autophagy - animal - Homo sapiens (human); hsa05164 Influenza A - Homo sapiens (human); ","IPR024054; IPR012340; IPR003029; IPR022967; IPR024055; ","\"Translation initiation factor 2, alpha subunit, middle domain; Nucleic acid-binding, OB-fold; S1 domain; RNA-binding domain, S1; Translation initiation factor 2, alpha subunit, C-terminal; \"\r"]
["P05362","Intercellular adhesion molecule 1 OS=Homo sapiens OX=9606 GN=ICAM1","ICAM1",57.825,31.083,8.6,4,7,4,0.964,0.99,1.055,1.007,1.039,0.952,0.996,0.927,"extracellular\r",{"$cut":{"chars":18982,"head":"GO:0044409 entry into host; GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0022414 reproductive process; GO:0042593 glucose homeostasis; GO:0009891 positive regulation of biosynthetic process; GO:0071384 cellular response to corticosteroid stimulus; GO:0070555 response to interleukin-1; GO:0009607 response to biotic stimulus; GO:0042110 T cell activation; GO:0097368 establishment of Sertoli cell barrier; GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; GO:0008360 regulation of cell shape; GO:0032535 regulation of cellular component size; GO:0044093 positive regulation of molecular function; GO:0071549 cellular response to dexamethasone stimulus; GO:0044057 regulation of system process; GO:0071322 cellular response to carbohydrate stimulus; GO:0051493 regulation of cytoskeleton organization; GO:0046718 viral entry into host cell; GO:0051051 negative regulation of transport; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0019229 regulation of vasoconstriction; GO:0002064 epithelial cell development; GO:0080090 regulation of primary metabolic process; GO:0002456 T cell mediated immunity; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0048870 cell motility; GO:0035296 regulation of tube diameter; GO:0051704 multi-organism process; GO:0071396 cellular response to lipid; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0050776 regulation of immune response; GO:0010243 response to organonitrogen compound; GO:0051092 positive regulation of NF-kappaB transcription factor activity; GO:0002526 acute inflammatory response; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0098602 single organism cell adhesion; GO:1902905 positive regulation of supramolecular fiber organization; GO:0048609 multicellular organismal reproductive process; GO:0060548 negative regulation of cell death; GO:0002687 positive regulation of leukocyte migration; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0030855 epithelial cell differentiation; GO:0000003 reproduction; GO:0044707 single-multicellular organism process; GO:0050880 regulation of blood vessel size; GO:0051806 entry into cell of other organism involved in symbiotic interaction; GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell; GO:1901700 response to oxygen-containing compound; GO:0003018 vascular process in circulatory system; GO:0071354 cellular response to interleukin-6; GO:0048519 negative regulation of biological process; GO:0046545 development of primary female sexual characteristics; GO:0042493 response to drug; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0051345 positive regulation of hydrolase activity; GO:2000145 regulation of cell motility; GO:0009889 regulation of biosynthetic process; GO:0043062 extracellular structure organization; GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell; GO:0070482 response to oxygen levels; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:0010959 regulation of metal ion transport; GO:0033500 carbohydrate homeostasis; GO:0035150 regulation of tube size; GO:0002449 lymphocyte mediated immunity; GO:0061458 reproductive system development; GO:0002438 acute inflammatory response to antigenic stimulus; GO:0048878 chemical homeostasis; GO:1901655 cellular response to ketone; GO:0045785 positive regulation of cell adhesion; GO:0006950 response to stress; GO:0032496 response to lipopolysaccharide; GO:0051270 regulation of cellular component movement; GO:0051924 regulation of calcium ion transport; GO:0032970 regulation of actin filament-based process; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:1903039 positive regulation of leukocyte cell-cell adhesion; GO:0002263 cell activation involved in immune respons"}},"GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0009897 external side of plasma membrane; GO:0098857 membrane microdomain; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0098589 membrane region; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030055 cell-substrate junction; GO:0045121 membrane raft; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0098552 side of membrane; GO:0031226 intrinsic component of plasma membrane; GO:0070161 anchoring junction; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0001772 immunological synapse; GO:0009986 cell surface; GO:0043230 extracellular organelle; ","GO:0038023 signaling receptor activity; GO:0050839 cell adhesion molecule binding; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0005102 receptor binding; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0005515 protein binding; GO:0005178 integrin binding; GO:0004888 transmembrane signaling receptor activity; GO:0004871 signal transducer activity; GO:0001618 virus receptor activity; GO:0099600 transmembrane receptor activity; GO:0032403 protein complex binding; ","K06490","ICAM1; intercellular adhesion molecule 1","hsa05144 Malaria - Homo sapiens (human); hsa05150 Staphylococcus aureus infection - Homo sapiens (human); hsa04650 Natural killer cell mediated cytotoxicity - Homo sapiens (human); hsa05323 Rheumatoid arthritis - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); hsa05167 Kaposi's sarcoma-associated herpesvirus infection - Homo sapiens (human); hsa05166 HTLV-I infection - Homo sapiens (human); hsa04670 Leukocyte transendothelial migration - Homo sapiens (human); hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human); hsa04514 Cell adhesion molecules (CAMs) - Homo sapiens (human); hsa05164 Influenza A - Homo sapiens (human); hsa04933 AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human); hsa04668 TNF signaling pathway - Homo sapiens (human); hsa05416 Viral myocarditis - Homo sapiens (human); hsa04064 NF-kappa B signaling pathway - Homo sapiens (human); hsa05143 African trypanosomiasis - Homo sapiens (human); ","IPR013768; IPR007110; IPR013783; IPR003988; IPR003599; IPR003987; ","\"Intercellular adhesion molecule, N-terminal; Immunoglobulin-like domain; Immunoglobulin-like fold; Intercellular adhesion molecule; Immunoglobulin subtype; Intercellular adhesion molecule/vascular cell adhesion molecule, N-terminal; \"\r"]
["P05386","60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1","RPLP1",11.514,21.663,28.9,2,7,1,0.884,0.75,0.853,1.067,1.205,1.154,1.378,0.00632,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0032270 positive regulation of cellular protein metabolic process; GO:0006518 peptide metabolic process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0002181 cytoplasmic translation; GO:0070972 protein localization to endoplasmic reticulum; GO:0006364 rRNA processing; GO:0044093 positive regulation of molecular function; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0033365 protein localization to organelle; GO:0051347 positive regulation of transferase activity; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0044419 interspecies interaction between organisms; GO:0008104 protein localization; GO:0006396 RNA processing; GO:0042325 regulation of phosphorylation; GO:0018130 heterocycle biosynthetic process; GO:0051174 regulation of phosphorus metabolic process; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0072657 protein localization to membrane; GO:0080090 regulation of primary metabolic process; GO:0042254 ribosome biogenesis; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032774 RNA biosynthetic process; GO:0045047 protein targeting to ER; GO:0031323 regulation of cellular metabolic process; GO:0051704 multi-organism process; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0050790 regulation of catalytic activity; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0048519 negative regulation of biological process; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0032147 activation of protein kinase activity; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0051338 regulation of transferase activity; GO:0044248 cellular catabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0034613 cellular protein localization; GO:0090150 establishment of protein localization to membrane; GO:0006414 translational elongation; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0045184 establishment of protein localization; GO:0051247 positive regulation of protein metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0051179 localization; GO:1901564 organonitrogen compound metabolic process; GO:0072594 establishment of protein localization to organelle; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0051649 establishment of localization in cell; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0009893 positive regulation of metabolic process; GO:0006413 translational initiation; GO:1901361 organic cyclic compound catabolic process; GO:0006412 translation; GO:0033674 positive regulation of kinase activity; GO:0033036 macromolecule localization; GO:0034470 ncRNA processing; GO:0016072 rRNA metabolic process; GO:0010468 regulation of gene expression; GO:0045937 positive regulation of phosphate metabolic process; GO:0043043 peptide biosynthetic process; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0006401 RNA catabolic process; GO:0016070 RNA metabolic process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0019083 viral transcription; GO:0043549 regulation of kinase activity; GO:0045859 regulation of protein kinase activity; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0006613 cotranslational protein targeting to membrane; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0016032 viral process; GO:0019080 viral gene expression; GO:0006886 intracellular protein transport; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0001932 regulation of protein phosphorylation; GO:0031401 positive regulation of protein modification process; GO:0006807 nitrogen compound metabolic process; GO:0001934 positive regulation of protein phosphorylation; GO:0045860 positive regulation of protein kinase activity; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0043085 positive regulation of catalytic activity; GO:0051641 cellular localization; GO:0070727 cellular macromolecule localization; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0051246 regulation of protein metabolic process; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0009056 catabolic process; GO:0034660 ncRNA metabolic process; GO:0065007 biological regulation; GO:0046700 heterocycle catabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0044421 extracellular region part; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0044391 ribosomal subunit; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030055 cell-substrate junction; GO:0044445 cytosolic part; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0022626 cytosolic ribosome; GO:0043229 intracellular organelle; GO:0005840 ribosome; GO:0043232 intracellular non-membrane-bounded organelle; GO:0022625 cytosolic large ribosomal subunit; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0015934 large ribosomal subunit; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0019209 kinase activator activity; GO:0030295 protein kinase activator activity; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0005515 protein binding; GO:0019207 kinase regulator activity; GO:0019887 protein kinase regulator activity; GO:0098772 molecular function regulator; GO:0003735 structural constituent of ribosome; GO:0005198 structural molecule activity; GO:0008047 enzyme activator activity; ","K02942","RP-LP1; large subunit ribosomal protein LP1","hsa03010 Ribosome - Homo sapiens (human); "]
["P05387","60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2","RPLP2",11.665,115.75,92.2,8,23,7,0.913,0.839,0.847,1.098,1.126,1.129,1.29,0.00082,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0072594 establishment of protein localization to organelle; GO:0006518 peptide metabolic process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0051649 establishment of localization in cell; GO:0002181 cytoplasmic translation; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0070972 protein localization to endoplasmic reticulum; GO:0006364 rRNA processing; GO:0006413 translational initiation; GO:1901361 organic cyclic compound catabolic process; GO:0033365 protein localization to organelle; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0044419 interspecies interaction between organisms; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0006412 translation; GO:0016072 rRNA metabolic process; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0072657 protein localization to membrane; GO:0043043 peptide biosynthetic process; GO:0042254 ribosome biogenesis; GO:1901360 organic cyclic compound metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032774 RNA biosynthetic process; GO:0045047 protein targeting to ER; GO:0043603 cellular amide metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0016070 RNA metabolic process; GO:0006401 RNA catabolic process; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0019083 viral transcription; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0046907 intracellular transport; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0044267 cellular protein metabolic process; GO:0006613 cotranslational protein targeting to membrane; GO:0048519 negative regulation of biological process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0016032 viral process; GO:0019080 viral gene expression; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0006886 intracellular protein transport; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0034613 cellular protein localization; GO:0009059 macromolecule biosynthetic process; GO:0090150 establishment of protein localization to membrane; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0006414 translational elongation; GO:0010629 negative regulation of gene expression; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0051179 localization; GO:0034660 ncRNA metabolic process; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; GO:1901564 organonitrogen compound metabolic process; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0044391 ribosomal subunit; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030055 cell-substrate junction; GO:0044445 cytosolic part; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0022626 cytosolic ribosome; GO:0043229 intracellular organelle; GO:0005840 ribosome; GO:0043232 intracellular non-membrane-bounded organelle; GO:0022625 cytosolic large ribosomal subunit; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0015934 large ribosomal subunit; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0003735 structural constituent of ribosome; GO:0005198 structural molecule activity; GO:0005488 binding; ","K02943","RP-LP2; large subunit ribosomal protein LP2","hsa03010 Ribosome - Homo sapiens (human); "]
["P05388","60S acidic ribosomal protein P0 OS=Homo sapiens OX=9606 GN=RPLP0","RPLP0",34.273,62.652,30.9,10,24,2,1.155,1.018,0.962,1.037,0.926,0.923,0.921,0.287,"cyto_nucl\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0072594 establishment of protein localization to organelle; GO:0006518 peptide metabolic process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0071345 cellular response to cytokine stimulus; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0051649 establishment of localization in cell; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0070972 protein localization to endoplasmic reticulum; GO:0006364 rRNA processing; GO:0006413 translational initiation; GO:1901361 organic cyclic compound catabolic process; GO:0033365 protein localization to organelle; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0006412 translation; GO:0044419 interspecies interaction between organisms; GO:0070887 cellular response to chemical stimulus; GO:0016072 rRNA metabolic process; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0010468 regulation of gene expression; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0072657 protein localization to membrane; GO:0034097 response to cytokine; GO:0043043 peptide biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0042254 ribosome biogenesis; GO:0032774 RNA biosynthetic process; GO:0045047 protein targeting to ER; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0043603 cellular amide metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0071353 cellular response to interleukin-4; GO:0051704 multi-organism process; GO:0006810 transport; GO:0016070 RNA metabolic process; GO:0006401 RNA catabolic process; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0090304 nucleic acid metabolic process; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0019083 viral transcription; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0046907 intracellular transport; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0071310 cellular response to organic substance; GO:0044267 cellular protein metabolic process; GO:0006613 cotranslational protein targeting to membrane; GO:0048519 negative regulation of biological process; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0016032 viral process; GO:0019080 viral gene expression; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0006886 intracellular protein transport; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0034613 cellular protein localization; GO:0009059 macromolecule biosynthetic process; GO:0090150 establishment of protein localization to membrane; GO:0070670 response to interleukin-4; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0051179 localization; GO:0009056 catabolic process; GO:0034660 ncRNA metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0071840 cellular component organization or biogenesis; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0030425 dendrite; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0044391 ribosomal subunit; GO:0044464 cell part; GO:0005622 intracellular; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0030055 cell-substrate junction; GO:0044445 cytosolic part; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0005924 cell-substrate adherens junction; GO:0022626 cytosolic ribosome; GO:0043229 intracellular organelle; GO:0005840 ribosome; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0022625 cytosolic large ribosomal subunit; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0036477 somatodendritic compartment; GO:0015934 large ribosomal subunit; GO:0035770 ribonucleoprotein granule; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0005198 structural molecule activity; GO:0003735 structural constituent of ribosome; ","K02941","RP-LP0; large subunit ribosomal protein LP0","hsa03010 Ribosome - Homo sapiens (human); "]
["P05413","Fatty acid-binding protein, heart OS=Homo sapiens OX=9606 GN=FABP3","FABP3",14.858,2.108,12,2,3,1,1.06,1.101,0.982,0.896,0.992,0.983,0.913,0.125,"cytoplasm\r","GO:0001101 response to acid chemical; GO:0065008 regulation of biological quality; GO:0046486 glycerolipid metabolic process; GO:0009891 positive regulation of biosynthetic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0019216 regulation of lipid metabolic process; GO:0044237 cellular metabolic process; GO:0008285 negative regulation of cell proliferation; GO:0051234 establishment of localization; GO:0055091 phospholipid homeostasis; GO:0046461 neutral lipid catabolic process; GO:0008152 metabolic process; GO:0009893 positive regulation of metabolic process; GO:0015718 monocarboxylic acid transport; GO:0071071 regulation of phospholipid biosynthetic process; GO:0006639 acylglycerol metabolic process; GO:0009719 response to endogenous stimulus; GO:0032787 monocarboxylic acid metabolic process; GO:0010562 positive regulation of phosphorus metabolic process; GO:0033036 macromolecule localization; GO:1901652 response to peptide; GO:0055088 lipid homeostasis; GO:0046889 positive regulation of lipid biosynthetic process; GO:0044765 single-organism transport; GO:0006629 lipid metabolic process; GO:0051174 regulation of phosphorus metabolic process; GO:0045937 positive regulation of phosphate metabolic process; GO:0006869 lipid transport; GO:0050801 ion homeostasis; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0044281 small molecule metabolic process; GO:0046320 regulation of fatty acid oxidation; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0055081 anion homeostasis; GO:0046942 carboxylic acid transport; GO:0031323 regulation of cellular metabolic process; GO:0006810 transport; GO:0010565 regulation of cellular ketone metabolic process; GO:1901575 organic substance catabolic process; GO:0010243 response to organonitrogen compound; GO:0032868 response to insulin; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0043434 response to peptide hormone; GO:0044710 single-organism metabolic process; GO:0046890 regulation of lipid biosynthetic process; GO:1901698 response to nitrogen compound; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0006082 organic acid metabolic process; GO:0043436 oxoacid metabolic process; GO:0046503 glycerolipid catabolic process; GO:0050794 regulation of cellular process; GO:2001245 regulation of phosphatidylcholine biosynthetic process; GO:0042127 regulation of cell proliferation; GO:1903725 regulation of phospholipid metabolic process; GO:1901700 response to oxygen-containing compound; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0046464 acylglycerol catabolic process; GO:0071704 organic substance metabolic process; GO:0033993 response to lipid; GO:0042493 response to drug; GO:0042592 homeostatic process; GO:0015908 fatty acid transport; GO:1902578 single-organism localization; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0044248 cellular catabolic process; GO:0070542 response to fatty acid; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0019433 triglyceride catabolic process; GO:0006638 neutral lipid metabolic process; GO:0016042 lipid catabolic process; GO:0044712 single-organism catabolic process; GO:0010876 lipid localization; GO:0071702 organic substance transport; GO:0010033 response to organic substance; GO:0006631 fatty acid metabolic process; GO:0044238 primary metabolic process; GO:0042632 cholesterol homeostasis; GO:0048518 positive regulation of biological process; GO:0015849 organic acid transport; GO:0045834 positive regulation of lipid metabolic process; GO:0044539 long-chain fatty acid import; GO:0006820 anion transport; GO:0015909 long-chain fatty acid transport; GO:0019217 regulation of fatty acid metabolic process; GO:0015711 organic anion transport; GO:0006641 triglyceride metabolic process; GO:0071073 positive regulation of phospholipid biosynthetic process; GO:0006811 ion transport; GO:0031325 positive regulation of cellular metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0055092 sterol homeostasis; GO:0044242 cellular lipid catabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:1903727 positive regulation of phospholipid metabolic process; GO:0009725 response to hormone; GO:0051179 localization; GO:0009056 catabolic process; GO:0065007 biological regulation; ","GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0016528 sarcoplasm; GO:0005623 cell; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0036041 long-chain fatty acid binding; GO:0005324 long-chain fatty acid transporter activity; GO:0050543 icosatetraenoic acid binding; GO:0043167 ion binding; GO:0005319 lipid transporter activity; GO:0043177 organic acid binding; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0033293 monocarboxylic acid binding; GO:0008092 cytoskeletal protein binding; GO:0031406 carboxylic acid binding; GO:0070538 oleic acid binding; GO:0005488 binding; GO:0008289 lipid binding; GO:0015245 fatty acid transporter activity; GO:0043168 anion binding; GO:0005504 fatty acid binding; GO:0036094 small molecule binding; GO:0005215 transporter activity; ","K08752","FABP3; fatty acid-binding protein 3, muscle and heart","hsa03320 PPAR signaling pathway - Homo sapiens (human); ","IPR000463; IPR012674; IPR000566; IPR011038; ","Cytosolic fatty-acid binding; Calycin; Lipocalin/cytosolic fatty-acid binding domain; Calycin-like; \r"]
["P05452","Tetranectin OS=Homo sapiens OX=9606 GN=CLEC3B","CLEC3B",22.537,138.68,56.4,10,29,10,1.279,1.221,1.226,0.765,0.759,0.784,0.619,1.56E-5,"extracellular\r","GO:0032270 positive regulation of cellular protein metabolic process; GO:0071560 cellular response to transforming growth factor beta stimulus; GO:0044699 single-organism process; GO:0071363 cellular response to growth factor stimulus; GO:0051234 establishment of localization; GO:0009893 positive regulation of metabolic process; GO:0009719 response to endogenous stimulus; GO:0070848 response to growth factor; GO:0070887 cellular response to chemical stimulus; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0051716 cellular response to stimulus; GO:0009888 tissue development; GO:0080090 regulation of primary metabolic process; GO:0001503 ossification; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0031323 regulation of cellular metabolic process; GO:0071559 response to transforming growth factor beta; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:0030282 bone mineralization; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0042221 response to chemical; GO:0032940 secretion by cell; GO:0019222 regulation of metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:1903317 regulation of protein maturation; GO:0010755 regulation of plasminogen activation; GO:0048856 anatomical structure development; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:1903319 positive regulation of protein maturation; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0002576 platelet degranulation; GO:0050896 response to stimulus; GO:0045862 positive regulation of proteolysis; GO:1902578 single-organism localization; GO:0010628 positive regulation of gene expression; GO:0031214 biomineral tissue development; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0010033 response to organic substance; GO:0030162 regulation of proteolysis; GO:0048518 positive regulation of biological process; GO:0045055 regulated exocytosis; GO:0051247 positive regulation of protein metabolic process; GO:0010954 positive regulation of protein processing; GO:0071495 cellular response to endogenous stimulus; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0070613 regulation of protein processing; GO:0051179 localization; GO:0010756 positive regulation of plasminogen activation; GO:0006887 exocytosis; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0042827 platelet dense granule; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0001652 granular component; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0044452 nucleolar part; GO:0005730 nucleolus; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0031089 platelet dense granule lumen; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0036143 kringle domain binding; GO:0097367 carbohydrate derivative binding; GO:0005488 binding; GO:0043167 ion binding; GO:0030246 carbohydrate binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0019904 protein domain specific binding; GO:0005515 protein binding; GO:0005509 calcium ion binding; GO:0008201 heparin binding; GO:0005539 glycosaminoglycan binding; GO:1901681 sulfur compound binding; ","K17520",null,null,"IPR001304; IPR016187; IPR016186; ","C-type lectin-like; C-type lectin fold; C-type lectin-like/link domain; \r"]
["P05455","Lupus La protein OS=Homo sapiens OX=9606 GN=SSB","SSB",46.836,77.663,40,17,28,17,1.015,0.976,1.043,0.993,1.002,1.017,0.993,0.751,"nucleus\r","GO:0075522 IRES-dependent viral translational initiation; GO:1903608 protein localization to cytoplasmic stress granule; GO:0006518 peptide metabolic process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0009451 RNA modification; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0002181 cytoplasmic translation; GO:0006413 translational initiation; GO:0002190 cap-independent translational initiation; GO:0033365 protein localization to organelle; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0006412 translation; GO:0044419 interspecies interaction between organisms; GO:0002183 cytoplasmic translational initiation; GO:0034470 ncRNA processing; GO:0006396 RNA processing; GO:0008334 histone mRNA metabolic process; GO:0043043 peptide biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0043603 cellular amide metabolic process; GO:0051704 multi-organism process; GO:0016070 RNA metabolic process; GO:0090304 nucleic acid metabolic process; GO:0008033 tRNA processing; GO:0044260 cellular macromolecule metabolic process; GO:0016071 mRNA metabolic process; GO:0019081 viral translation; GO:0006725 cellular aromatic compound metabolic process; GO:0019058 viral life cycle; GO:0044267 cellular protein metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0016032 viral process; GO:0019080 viral gene expression; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0034613 cellular protein localization; GO:0006400 tRNA modification; GO:0009987 cellular process; GO:0002192 IRES-dependent translational initiation; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0070727 cellular macromolecule localization; GO:0006399 tRNA metabolic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0051179 localization; GO:0043412 macromolecule modification; GO:0034660 ncRNA metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0043229 intracellular organelle; GO:0000784 nuclear chromosome, telomeric region; GO:0000781 chromosome, telomeric region; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0098687 chromosomal region; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044454 nuclear chromosome part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0000228 nuclear chromosome; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003729 mRNA binding; GO:0003723 RNA binding; GO:1901265 nucleoside phosphate binding; GO:0000049 tRNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0036094 small molecule binding; ","K11090","LA; lupus La protein","hsa05322 Systemic lupus erythematosus - Homo sapiens (human); ","IPR011991; IPR006630; IPR000504; IPR012677; IPR014886; ","\"Winged helix-turn-helix DNA-binding domain; RNA-binding protein Lupus La; RNA recognition motif domain; Nucleotide-binding alpha-beta plait domain; La protein, RNA-binding domain; \"\r"]
["P05534","HLA class I histocompatibility antigen, A-24 alpha chain OS=Homo sapiens OX=9606 GN=HLA-A","HLA-A",40.688,-2,27.7,10,23,1,0.858,0.846,0.678,1.193,1.174,1.237,1.513,0.00572,"extracellular\r","GO:0044700 single organism signaling; GO:0007166 cell surface receptor signaling pathway; GO:0002698 negative regulation of immune effector process; GO:0071346 cellular response to interferon-gamma; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; GO:0031347 regulation of defense response; GO:0071345 cellular response to cytokine stimulus; GO:0060333 interferon-gamma-mediated signaling pathway; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0045088 regulation of innate immune response; GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I; GO:0050777 negative regulation of immune response; GO:0044419 interspecies interaction between organisms; GO:0002697 regulation of immune effector process; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0070887 cellular response to chemical stimulus; GO:0051716 cellular response to stimulus; GO:0034097 response to cytokine; GO:0048002 antigen processing and presentation of peptide antigen; GO:0034340 response to type I interferon; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0002716 negative regulation of natural killer cell mediated immunity; GO:0023052 signaling; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0002683 negative regulation of immune system process; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0048583 regulation of response to stimulus; GO:0042269 regulation of natural killer cell mediated cytotoxicity; GO:0002682 regulation of immune system process; GO:0006952 defense response; GO:0050794 regulation of cellular process; GO:0060337 type I interferon signaling pathway; GO:0031341 regulation of cell killing; GO:0071310 cellular response to organic substance; GO:0002704 negative regulation of leukocyte mediated immunity; GO:0002715 regulation of natural killer cell mediated immunity; GO:0080134 regulation of response to stress; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0002706 regulation of lymphocyte mediated immunity; GO:0045087 innate immune response; GO:0045953 negative regulation of natural killer cell mediated cytotoxicity; GO:0016032 viral process; GO:0002707 negative regulation of lymphocyte mediated immunity; GO:0071357 cellular response to type I interferon; GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; GO:0019221 cytokine-mediated signaling pathway; GO:0009987 cellular process; GO:0031348 negative regulation of defense response; GO:0001910 regulation of leukocyte mediated cytotoxicity; GO:0006950 response to stress; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:0031342 negative regulation of cell killing; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0034341 response to interferon-gamma; GO:0048585 negative regulation of response to stimulus; GO:0045824 negative regulation of innate immune response; GO:0002703 regulation of leukocyte mediated immunity; GO:0019882 antigen processing and presentation; GO:0042270 protection from natural killer cell mediated cytotoxicity; GO:0006955 immune response; GO:0001911 negative regulation of leukocyte mediated cytotoxicity; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0098552 side of membrane; GO:0010008 endosome membrane; GO:0030666 endocytic vesicle membrane; GO:0098797 plasma membrane protein complex; GO:0012506 vesicle membrane; GO:0044440 endosomal part; GO:0030135 coated vesicle; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0098553 lumenal side of endoplasmic reticulum membrane; GO:0042612 MHC class I protein complex; GO:0030133 transport vesicle; GO:0043234 protein complex; GO:0030176 integral component of endoplasmic reticulum membrane; GO:0043230 extracellular organelle; GO:0030658 transport vesicle membrane; GO:0005783 endoplasmic reticulum; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0042611 MHC protein complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0055038 recycling endosome membrane; GO:0030662 coated vesicle membrane; GO:0055037 recycling endosome; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0030670 phagocytic vesicle membrane; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0031227 intrinsic component of endoplasmic reticulum membrane; GO:0005768 endosome; GO:0031901 early endosome membrane; GO:0030139 endocytic vesicle; GO:0012507 ER to Golgi transport vesicle membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0030134 ER to Golgi transport vesicle; GO:0012505 endomembrane system; GO:0045335 phagocytic vesicle; GO:0016021 integral component of membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0044432 endoplasmic reticulum part; GO:0009986 cell surface; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:0030881 beta-2-microglobulin binding; GO:0046977 TAP binding; GO:0042277 peptide binding; GO:0005488 binding; GO:0005515 protein binding; GO:0033218 amide binding; GO:0042605 peptide antigen binding; GO:0003823 antigen binding; ",{"$nulls":3},"IPR007110; IPR013783; IPR010579; IPR011161; IPR001039; IPR011162; IPR003597; ","\"Immunoglobulin-like domain; Immunoglobulin-like fold; MHC class I, alpha chain, C-terminal; MHC class I-like antigen recognition-like; MHC class I alpha chain, alpha1 alpha2 domains; MHC classes I/II-like antigen recognition protein; Immunoglobulin C1-set; \"\r"]
["P05546","Heparin cofactor 2 OS=Homo sapiens OX=9606 GN=SERPIND1","SERPIND1",57.07,110.19,28.7,12,34,12,1.063,1.056,1.018,0.946,0.958,0.934,0.905,0.00284,"extracellular\r","GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0010951 negative regulation of endopeptidase activity; GO:0060255 regulation of macromolecule metabolic process; GO:0044699 single-organism process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0007599 hemostasis; GO:0051346 negative regulation of hydrolase activity; GO:0009611 response to wounding; GO:0009605 response to external stimulus; GO:0010466 negative regulation of peptidase activity; GO:0008152 metabolic process; GO:0009987 cellular process; GO:0052548 regulation of endopeptidase activity; GO:0045861 negative regulation of proteolysis; GO:0050878 regulation of body fluid levels; GO:0006950 response to stress; GO:0080090 regulation of primary metabolic process; GO:0030162 regulation of proteolysis; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0006935 chemotaxis; GO:0032501 multicellular organismal process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0009892 negative regulation of metabolic process; GO:0008218 bioluminescence; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0042060 wound healing; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0051246 regulation of protein metabolic process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0065009 regulation of molecular function; GO:0051248 negative regulation of protein metabolic process; GO:0019222 regulation of metabolic process; GO:0042330 taxis; GO:0044092 negative regulation of molecular function; GO:0040011 locomotion; GO:0050817 coagulation; GO:0052547 regulation of peptidase activity; GO:0065007 biological regulation; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:0043167 ion binding; GO:0061134 peptidase regulator activity; GO:0008201 heparin binding; GO:0098772 molecular function regulator; GO:0004857 enzyme inhibitor activity; GO:1901681 sulfur compound binding; GO:0004866 endopeptidase inhibitor activity; GO:0004867 serine-type endopeptidase inhibitor activity; GO:0097367 carbohydrate derivative binding; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0030414 peptidase inhibitor activity; GO:0061135 endopeptidase regulator activity; GO:0043168 anion binding; GO:0005539 glycosaminoglycan binding; ","K03912","SERPIND1; heparin cofactor II","hsa04610 Complement and coagulation cascades - Homo sapiens (human); ","IPR023796; IPR033831; ","Serpin domain; Heparin cofactor II; \r"]
["P05556","Integrin beta-1 OS=Homo sapiens OX=9606 GN=ITGB1","ITGB1",88.414,152.78,25.6,19,39,19,1.138,1.106,1.108,0.891,0.899,0.851,0.788,0.000244,"extracellular\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0044409 entry into host; GO:0090130 tissue migration; GO:0010941 regulation of cell death; GO:0022414 reproductive process; GO:0043009 chordate embryonic development; GO:0044237 cellular metabolic process; GO:0055098 response to low-density lipoprotein particle; GO:0021932 hindbrain radial glia guided cell migration; GO:0001525 angiogenesis; GO:0008152 metabolic process; GO:0044093 positive regulation of molecular function; GO:0007160 cell-matrix adhesion; GO:0055094 response to lipoprotein particle; GO:0044770 cell cycle phase transition; GO:0009790 embryo development; GO:0048598 embryonic morphogenesis; GO:0046718 viral entry into host cell; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0060537 muscle tissue development; GO:0050901 leukocyte tethering or rolling; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0002520 immune system development; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0048870 cell motility; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0006810 transport; GO:1902532 negative regulation of intracellular signal transduction; GO:0007612 learning; GO:0048583 regulation of response to stimulus; GO:0098602 single organism cell adhesion; GO:0044260 cellular macromolecule metabolic process; GO:0033631 cell-cell adhesion mediated by integrin; GO:0060548 negative regulation of cell death; GO:0048609 multicellular organismal reproductive process; GO:0072359 circulatory system development; GO:0055001 muscle cell development; GO:0000003 reproduction; GO:0044707 single-multicellular organism process; GO:1903076 regulation of protein localization to plasma membrane; GO:0051806 entry into cell of other organism involved in symbiotic interaction; GO:1990138 neuron projection extension; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0030098 lymphocyte differentiation; GO:0009653 anatomical structure morphogenesis; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0051345 positive regulation of hydrolase activity; GO:0043062 extracellular structure organization; GO:0061061 muscle structure development; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0030902 hindbrain development; GO:0046580 negative regulation of Ras protein signal transduction; GO:0006950 response to stress; GO:0009416 response to light stimulus; GO:0010927 cellular component assembly involved in morphogenesis; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0006996 organelle organization; GO:0048589 developmental growth; GO:0035023 regulation of Rho protein signal transduction; GO:0040007 growth; GO:1903827 regulation of cellular protein localization; GO:0008284 positive regulation of cell proliferation; GO:0051093 negative regulation of developmental process; GO:0031623 receptor internalization; GO:0009968 negative regulation of signal transduction; GO:0051674 localization of cell; GO:0044246 regulation of multicellular organismal metabolic process; GO:0001568 blood vessel development; GO:0033627 cell adhesion mediated by integrin; GO:0023051 regulation of signaling; GO:0048869 cellular developmental process; GO:0048666 neuron development; GO:0044699 single-organism process; GO:0048729 tissue morphogenesis; GO:1904375 regulation of protein localization to cell periphery; GO:0016337 single organismal cell-cell adhesion; GO:0007165 signal transduction; GO:0032990 cell part morphogenesis; GO:0048858 cell projection morphogenesis; GO:0030198 extracellular matrix organization; GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules; GO:0051726 regulation of cell cycle; GO:0048675 axon extension; GO:0071402 cellular response to lipoprotein particle stimulus; GO:0043112 receptor metabolic process; GO:0098609 cell-cell adhesion; GO:0001944 vasculature development; GO:0023052 signaling; GO:0007229 integrin-mediated signaling pathway; GO:0010942 positive regulation of cell death; GO:0001667 ameboidal-type cell migration; GO:2000811 negative regulation of anoikis; GO:0043087 regulation of GTPase activity; GO:0065009 regulation of molecular function; GO:0006952 defense response; GO:0014706 striated muscle tissue development; GO:0016043 cellular component organization; GO:0016477 cell migration; GO:0016358 dendrite development; GO:0043069 negative regulation of programmed cell death; GO:0048738 cardiac muscle tissue development; GO:0043534 blood vessel endothelial cell migration; GO:1903829 positive regulation of cellular protein localization; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0019058 viral life cycle; GO:0043065 positive regulation of apoptotic process; GO:0071704 organic substance metabolic process; GO:0000904 cell morphogenesis involved in differentiation; GO:0007369 gastrulation; GO:1905475 regulation of protein localization to membrane; GO:0030154 cell differentiation; GO:0043066 negative regulation of apoptotic process; GO:0070925 organelle assembly; GO:0016032 viral process; GO:0045595 regulation of cell differentiation; GO:0051146 striated muscle cell differentiation; GO:0009792 embryo development ending in birth or egg hatching; GO:0002042 cell migration involved in sprouting angiogenesis; GO:0007611 learning or memory; GO:0030097 hemopoiesis; GO:0043085 positive regulation of catalytic activity; GO:0048332 mesoderm morphogenesis; GO:0071495 cellular response to endogenous stimulus; GO:0044703 multi-organism reproductive process; GO:0042692 muscle cell differentiation; GO:0022402 cell cycle process; GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules; GO:0051058 negative regulation of small GTPase mediated signal transduction; GO:0007049 cell cycle; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0045321 leukocyte activation; GO:0007166 cell surface receptor signaling pathway; GO:0008354 germ cell migration; GO:0007420 brain development; GO:0032989 cellular component morphogenesis; GO:0050877 neurological system process; GO:0007610 behavior; GO:0022610 biological adhesion; GO:1903729 regulation of plasma membrane organization; GO:0043542 endothelial cell migration; GO:0030036 actin cytoskeleton organization; GO:0007507 heart development; GO:0032879 regulation of localization; GO:0044702 single organism reproductive process; GO:0007155 cell adhesion; GO:0010710 regulation of collagen catabolic process; GO:0009719 response to endogenous stimulus; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0051056 regulation of small GTPase mediated signal transduction; GO:0044765 single-organism transport; GO:0007399 nervous system development; GO:0016049 cell growth; GO:0009894 regulation of catabolic process; GO:0001707 mesoderm formation; GO:0019953 sexual reproduction; GO:0048812 neuron projection morphogenesis; GO:0032501 multicellular organismal process; GO:0030183 B cell differentiation; GO:0007498 mesoderm development; GO:0000902 cell morphogenesis; GO:0048513 animal organ development; GO:0050900 leukocyte migration; GO:0010631 epithelial cell migration; GO:0055002 striated muscle cell development; GO:0051336 regulation of hydrolase activity; GO:0001701 in utero embryonic development; GO:0044710 single-organism metabolic process; GO:0007417 central nervous system development; GO:0050790 regulation of catalytic activity; GO:0002682 regulation of immune system process; GO:0097435 supramolecular fiber organization; GO:0043068 positive regulation of programmed cell death; GO:0044708 single-organism behavior; GO:0050794 regulation of cellular process; GO:0042127 regulation of cell proliferation; GO:0009628 response to abiotic stimulus; GO:0043067 regulation of programmed cell death; GO:2000209 regulation of anoikis; GO:0048523 negative regulation of cellular process; GO:0090132 epithelium migration; GO:1903078 positive regulation of protein localization to plasma membrane; GO:1905477 positive regulation of protein localization to membrane; GO:0051239 regulation of multicellular organismal process; GO:0060341 regulation of cellular localization; GO:0055007 cardiac muscle cell differentiation; GO:1902578 single-organism localization; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0030239 myofibril assembly; GO:0007409 axonogenesis; GO:0006898 receptor-mediated endocytosis; GO:0007275 multicellular organism development; GO:0032880 regulation of protein localization; GO:0007010 cytoskeleton organization; GO:0090003 regulation of establishment of protein localization to plasma membrane; GO:0009966 regulation of signal transduction; GO:1904377 positive regulation of protein localization to cell periphery; GO:0044772 mitotic cell cycle phase transition; GO:0008542 visual learning; GO:1902531 regulation of intracellular signal transduction; GO:0035051 cardiocyte differentiation; GO:0043547 positive regulation of GTPase activity; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0061756 leukocyte adhesion to vascular endothelial cell; GO:0060560 developmental growth involved in morphogenesis; GO:0072358 cardiovascular system development; GO:0045165 cell fate commitment; GO:0030182 neuron differentiation; GO:1904951 positive regulation of establishment of protein localization; GO:0045123 cellular extravasation; GO:0030029 actin filament-based process; GO:0006928 movement of cell or subcellular component; GO:0001775 cell activation; GO:0051179 localization; GO:0010712 regulation of collagen metabolic process; GO:0050793 regulation of developmental process; GO:0035024 negative regulation of Rho protein signal transduction; GO:0022008 neurogenesis; GO:0044764 multi-organism cellular process; GO:0034113 heterotypic cell-cell adhesion; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0060322 head development; GO:0009314 response to radiation; GO:0048514 blood vessel morphogenesis; GO:0001708 cell fate specification; GO:0045596 negative regulation of cell differentiation; GO:0070887 cellular response to chemical stimulus; GO:0002040 sprouting angiogenesis; GO:0032502 developmental process; GO:0031032 actomyosin structure organization; GO:0009888 tissue development; GO:0001704 formation of primary germ layer; GO:0007632 visual behavior; GO:0002521 leukocyte differentiation; GO:0048522 positive regulation of cellular process; GO:1902589 single-organism organelle organization; GO:0030260 entry into host cell; GO:0050789 regulation of biological process; GO:0045214 sarcomere organization; GO:0042221 response to chemical; GO:0030030 cell projection organization; GO:0051828 entry into other organism involved in symbiotic interaction; GO:0022412 cellular process involved in reproduction in multicellular organism; GO:0048813 dendrite morphogenesis; GO:0021943 formation of radial glial scaffolds; GO:0019222 regulation of metabolic process; GO:0040011 locomotion; GO:0048856 anatomical structure development; GO:0007159 leukocyte cell-cell adhesion; GO:0046578 regulation of Ras protein signal transduction; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0070201 regulation of establishment of protein localization; GO:0090004 positive regulation of establishment of protein localization to plasma membrane; GO:0050890 cognition; GO:0021535 cell migration in hindbrain; GO:0000082 G1/S transition of mitotic cell cycle; GO:0009987 cellular process; GO:0042113 B cell activation; GO:0071404 cellular response to low-density lipoprotein particle stimulus; GO:0003008 system process; GO:0044843 cell cycle G1/S phase transition; GO:0046649 lymphocyte activation; GO:0048585 negative regulation of response to stimulus; GO:0031175 neuron projection development; GO:0051701 interaction with host; GO:0006897 endocytosis; GO:0048333 mesodermal cell differentiation; GO:0048518 positive regulation of biological process; GO:0007276 gamete generation; GO:0048534 hematopoietic or lymphoid organ development; GO:0032504 multicellular organism reproduction; GO:0061564 axon development; GO:0031589 cell-substrate adhesion; GO:0006968 cellular defense response; GO:0048588 developmental cell growth; GO:0044767 single-organism developmental process; GO:0051128 regulation of cellular component organization; GO:0008306 associative learning; GO:0007161 calcium-independent cell-matrix adhesion; GO:0065007 biological regulation; ","GO:0030425 dendrite; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0009897 external side of plasma membrane; GO:0071437 invadopodium; GO:0098857 membrane microdomain; GO:0032587 ruffle membrane; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0071438 invadopodium membrane; GO:0005887 integral component of plasma membrane; GO:0098858 actin-based cell projection; GO:0005623 cell; GO:0032155 cell division site part; GO:0014704 intercalated disc; GO:0043197 dendritic spine; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0098590 plasma membrane region; GO:0031256 leading edge membrane; GO:0043209 myelin sheath; GO:0005622 intracellular; GO:0098589 membrane region; GO:0030027 lamellipodium; GO:0030175 filopodium; GO:0097060 synaptic membrane; GO:0043005 neuron projection; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0034667 integrin alpha3-beta1 complex; GO:0005924 cell-substrate adherens junction; GO:0098552 side of membrane; GO:0031252 cell leading edge; GO:0031226 intrinsic component of plasma membrane; GO:0042995 cell projection; GO:0098797 plasma membrane protein complex; GO:0098802 plasma membrane receptor complex; GO:0043235 receptor complex; GO:0070161 anchoring junction; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0098794 postsynapse; GO:0043234 protein complex; GO:0042383 sarcolemma; GO:0043230 extracellular organelle; GO:0098636 protein complex involved in cell adhesion; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0044291 cell-cell contact zone; GO:0030054 cell junction; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0034665 integrin alpha1-beta1 complex; GO:0031224 intrinsic component of membrane; GO:0035748 myelin sheath abaxonal region; GO:0044424 intracellular part; GO:0005911 cell-cell junction; GO:0048770 pigment granule; GO:0055037 recycling endosome; GO:0044309 neuron spine; GO:0044425 membrane part; GO:0044464 cell part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0005912 adherens junction; GO:0048471 perinuclear region of cytoplasm; GO:0005768 endosome; GO:0032154 cleavage furrow; GO:0045121 membrane raft; GO:0044456 synapse part; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0097610 cell surface furrow; GO:0031594 neuromuscular junction; GO:0042470 melanosome; GO:0032153 cell division site; GO:0034666 integrin alpha2-beta1 complex; GO:0012505 endomembrane system; GO:0008305 integrin complex; GO:0044463 cell projection part; GO:0016021 integral component of membrane; GO:0045202 synapse; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0034678 integrin alpha8-beta1 complex; GO:0044459 plasma membrane part; GO:0001726 ruffle; GO:0031253 cell projection membrane; GO:0034681 integrin alpha11-beta1 complex; GO:0009986 cell surface; GO:0034677 integrin alpha7-beta1 complex; GO:0044444 cytoplasmic part; GO:0034680 integrin alpha10-beta1 complex; ","GO:0038023 signaling receptor activity; GO:0098639 collagen binding involved in cell-matrix adhesion; GO:0001968 fibronectin binding; GO:0046982 protein heterodimerization activity; GO:0005102 receptor binding; GO:0015026 coreceptor activity; GO:0043167 ion binding; GO:0046983 protein dimerization activity; GO:0044877 macromolecular complex binding; GO:0005515 protein binding; GO:0005178 integrin binding; GO:0004871 signal transducer activity; GO:0050840 extracellular matrix binding; GO:0001618 virus receptor activity; GO:0002020 protease binding; GO:0050839 cell adhesion molecule binding; GO:0060089 molecular transducer activity; GO:0008092 cytoskeletal protein binding; GO:0004872 receptor activity; GO:0098631 protein binding involved in cell adhesion; GO:0043236 laminin binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0003779 actin binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005518 collagen binding; GO:0019899 enzyme binding; GO:0098634 protein binding involved in cell-matrix adhesion; GO:0032403 protein complex binding; ","K05719","ITGB1; integrin beta 1","hsa05100 Bacterial invasion of epithelial cells - Homo sapiens (human); hsa04015 Rap1 signaling pathway - Homo sapiens (human); hsa04530 Tight junction - Homo sapiens (human); hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa05140 Leishmaniasis - Homo sapiens (human); hsa05222 Small cell lung cancer - Homo sapiens (human); hsa04670 Leukocyte transendothelial migration - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa04512 ECM-receptor interaction - Homo sapiens (human); hsa04514 Cell adhesion molecules (CAMs) - Homo sapiens (human); hsa05131 Shigellosis - Homo sapiens (human); hsa05145 Toxoplasmosis - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa05414 Dilated cardiomyopathy (DCM) - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa04611 Platelet activation - Homo sapiens (human); hsa05133 Pertussis - Homo sapiens (human); hsa04360 Axon guidance - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); hsa05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human); hsa05410 Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human); ","IPR033760; IPR002369; IPR012896; IPR016201; IPR013111; IPR032695; IPR002035; IPR014836; ","\"Integrin beta N-terminal; Integrin beta subunit, VWA domain; Integrin beta subunit, tail; PSI domain; EGF-like domain, extracellular; Integrin domain; von Willebrand factor, type A; Integrin beta subunit, cytoplasmic domain; \"\r"]
["P05783","Keratin, type I cytoskeletal 18 OS=Homo sapiens OX=9606 GN=KRT18","KRT18",48.057,45.95,33.3,17,21,8,1.062,1.063,1.222,0.823,0.934,0.857,0.781,0.0145,"mitochondria\r","GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0010256 endomembrane system organization; GO:0031424 keratinization; GO:0007166 cell surface receptor signaling pathway; GO:0048869 cellular developmental process; GO:0090002 establishment of protein localization to plasma membrane; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0071345 cellular response to cytokine stimulus; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0022610 biological adhesion; GO:0009913 epidermal cell differentiation; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0006893 Golgi to plasma membrane transport; GO:0006915 apoptotic process; GO:0007155 cell adhesion; GO:0008544 epidermis development; GO:0034612 response to tumor necrosis factor; GO:0044419 interspecies interaction between organisms; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:1904019 epithelial cell apoptotic process; GO:0070887 cellular response to chemical stimulus; GO:0044765 single-organism transport; GO:0097284 hepatocyte apoptotic process; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0060429 epithelium development; GO:0043588 skin development; GO:0030216 keratinocyte differentiation; GO:0009888 tissue development; GO:0072657 protein localization to membrane; GO:0034097 response to cytokine; GO:0070268 cornification; GO:0098609 cell-cell adhesion; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0007009 plasma membrane organization; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0033209 tumor necrosis factor-mediated signaling pathway; GO:0006810 transport; GO:1902589 single-organism organelle organization; GO:0048513 animal organ development; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0060548 negative regulation of cell death; GO:0048856 anatomical structure development; GO:0030855 epithelial cell differentiation; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0097191 extrinsic apoptotic signaling pathway; GO:0043069 negative regulation of programmed cell death; GO:0097190 apoptotic signaling pathway; GO:0071356 cellular response to tumor necrosis factor; GO:0071310 cellular response to organic substance; GO:0043067 regulation of programmed cell death; GO:0048193 Golgi vesicle transport; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:1990778 protein localization to cell periphery; GO:0043000 Golgi to plasma membrane CFTR protein transport; GO:0009653 anatomical structure morphogenesis; GO:0030154 cell differentiation; GO:1902578 single-organism localization; GO:0043066 negative regulation of apoptotic process; GO:0016032 viral process; GO:0043001 Golgi to plasma membrane protein transport; GO:1902580 single-organism cellular localization; GO:0007275 multicellular organism development; GO:0034613 cellular protein localization; GO:0007010 cytoskeleton organization; GO:0090150 establishment of protein localization to membrane; GO:0009987 cellular process; GO:0019221 cytokine-mediated signaling pathway; GO:0045104 intermediate filament cytoskeleton organization; GO:0098876 vesicle-mediated transport to the plasma membrane; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0045103 intermediate filament-based process; GO:0044802 single-organism membrane organization; GO:0071702 organic substance transport; GO:0010033 response to organic substance; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0072659 protein localization to plasma membrane; GO:0008219 cell death; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0061024 membrane organization; GO:0012501 programmed cell death; GO:0006892 post-Golgi vesicle-mediated transport; GO:0051179 localization; GO:0007049 cell cycle; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0044421 extracellular region part; GO:0044450 microtubule organizing center part; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0005913 cell-cell adherens junction; GO:0099080 supramolecular complex; GO:0005911 cell-cell junction; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0005815 microtubule organizing center; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0005912 adherens junction; GO:0048471 perinuclear region of cytoplasm; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0034451 centriolar satellite; GO:0070161 anchoring junction; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0045095 keratin filament; GO:0099081 supramolecular polymer; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0045111 intermediate filament cytoskeleton; GO:0005813 centrosome; GO:0005882 intermediate filament; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0098641 cadherin binding involved in cell-cell adhesion; GO:0050839 cell adhesion molecule binding; GO:0003723 RNA binding; GO:0098631 protein binding involved in cell adhesion; GO:0005488 binding; GO:0045296 cadherin binding; GO:0003676 nucleic acid binding; GO:0097110 scaffold protein binding; GO:0005515 protein binding; GO:0098632 protein binding involved in cell-cell adhesion; GO:0005198 structural molecule activity; ","K07604","KRT1; type I keratin, acidic","hsa05150 Staphylococcus aureus infection - Homo sapiens (human); hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human); hsa04915 Estrogen signaling pathway - Homo sapiens (human); "]
["P05997","Collagen alpha-2(V) chain OS=Homo sapiens OX=9606 GN=COL5A2","COL5A2",144.91,2.5505,1.3,2,2,2,1.131,1.095,1.136,0.875,0.912,0.873,0.791,0.000218,"endoplasmic reticulum\r","GO:0051093 negative regulation of developmental process; GO:0001101 response to acid chemical; GO:0030199 collagen fibril organization; GO:0044236 multicellular organism metabolic process; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0008152 metabolic process; GO:0009719 response to endogenous stimulus; GO:0043170 macromolecule metabolic process; GO:0030198 extracellular matrix organization; GO:0045596 negative regulation of cell differentiation; GO:0044259 multicellular organismal macromolecule metabolic process; GO:0070887 cellular response to chemical stimulus; GO:0090596 sensory organ morphogenesis; GO:0030574 collagen catabolic process; GO:0032502 developmental process; GO:0043200 response to amino acid; GO:0051716 cellular response to stimulus; GO:0043588 skin development; GO:0071822 protein complex subunit organization; GO:0048592 eye morphogenesis; GO:0001503 ossification; GO:0044763 single-organism cellular process; GO:0032501 multicellular organismal process; GO:0071417 cellular response to organonitrogen compound; GO:0010243 response to organonitrogen compound; GO:0048513 animal organ development; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:1901699 cellular response to nitrogen compound; GO:0044710 single-organism metabolic process; GO:0071230 cellular response to amino acid stimulus; GO:1901698 response to nitrogen compound; GO:0009887 animal organ morphogenesis; GO:0048856 anatomical structure development; GO:0097435 supramolecular fiber organization; GO:0001501 skeletal system development; GO:1903224 regulation of endodermal cell differentiation; GO:2000026 regulation of multicellular organismal development; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0071310 cellular response to organic substance; GO:1901700 response to oxygen-containing compound; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:0071704 organic substance metabolic process; GO:0009653 anatomical structure morphogenesis; GO:0044243 multicellular organismal catabolic process; GO:0001654 eye development; GO:0045992 negative regulation of embryonic development; GO:0010470 regulation of gastrulation; GO:0071229 cellular response to acid chemical; GO:0043062 extracellular structure organization; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0044712 single-organism catabolic process; GO:0048731 system development; GO:0010033 response to organic substance; GO:0043933 macromolecular complex subunit organization; GO:2000542 negative regulation of gastrulation; GO:1901701 cellular response to oxygen-containing compound; GO:0045995 regulation of embryonic development; GO:0044767 single-organism developmental process; GO:0071495 cellular response to endogenous stimulus; GO:1903225 negative regulation of endodermal cell differentiation; GO:0022603 regulation of anatomical structure morphogenesis; GO:0032963 collagen metabolic process; GO:0007423 sensory organ development; GO:0009056 catabolic process; GO:0050793 regulation of developmental process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0098643 banded collagen fibril; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0005737 cytoplasm; GO:0005583 fibrillar collagen trimer; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0044420 extracellular matrix component; GO:0005581 collagen trimer; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005788 endoplasmic reticulum lumen; GO:0098644 complex of collagen trimers; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0099081 supramolecular polymer; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031012 extracellular matrix; GO:0044432 endoplasmic reticulum part; GO:0005588 collagen type V trimer; GO:0005578 proteinaceous extracellular matrix; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0005201 extracellular matrix structural constituent; GO:0005488 binding; GO:0043167 ion binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0005198 structural molecule activity; GO:0046332 SMAD binding; ","K19721","COL5AS; collagen, type V/XI/XXIV/XXVII, alpha","hsa04974 Protein digestion and absorption - Homo sapiens (human); ","IPR001007; IPR000885; IPR014716; ","\"VWFC domain; Fibrillar collagen, C-terminal; Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1; \"\r"]
["P06132","Uroporphyrinogen decarboxylase OS=Homo sapiens OX=9606 GN=UROD","UROD",40.786,14.097,13.1,4,5,4,0.888,1.021,0.908,1.122,1.055,1.011,1.132,0.0775,"cytoplasm\r","GO:0051188 cofactor biosynthetic process; GO:0046148 pigment biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0006783 heme biosynthetic process; GO:0044699 single-organism process; GO:0046501 protoporphyrinogen IX metabolic process; GO:0009058 biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0042168 heme metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0006778 porphyrin-containing compound metabolic process; GO:0006782 protoporphyrinogen IX biosynthetic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009987 cellular process; GO:0018130 heterocycle biosynthetic process; GO:0044711 single-organism biosynthetic process; GO:0042440 pigment metabolic process; GO:0006779 porphyrin-containing compound biosynthetic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0051186 cofactor metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0044710 single-organism metabolic process; GO:0033013 tetrapyrrole metabolic process; GO:0033014 tetrapyrrole biosynthetic process; GO:1901362 organic cyclic compound biosynthetic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0043229 intracellular organelle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0003824 catalytic activity; GO:0005488 binding; GO:0016830 carbon-carbon lyase activity; GO:0016831 carboxy-lyase activity; GO:0016829 lyase activity; GO:0004853 uroporphyrinogen decarboxylase activity; GO:0005515 protein binding; ","K01599","hemE; uroporphyrinogen decarboxylase [EC:4.1.1.37]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00860 Porphyrin and chlorophyll metabolism - Homo sapiens (human); ","IPR000257; ","Uroporphyrinogen decarboxylase (URO-D); \r"]
["P06276","Cholinesterase OS=Homo sapiens OX=9606 GN=BCHE","BCHE",68.417,4.3791,3.2,2,3,2,0.893,0.975,1.357,0.755,1.089,0.93,0.86,0.431,"extracellular\r","GO:0001101 response to acid chemical; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0051593 response to folic acid; GO:0044237 cellular metabolic process; GO:0050877 neurological system process; GO:0008285 negative regulation of cell proliferation; GO:0007610 behavior; GO:0019695 choline metabolic process; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0010646 regulation of cell communication; GO:0048545 response to steroid hormone; GO:0009719 response to endogenous stimulus; GO:0033273 response to vitamin; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0014070 response to organic cyclic compound; GO:0050805 negative regulation of synaptic transmission; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0032501 multicellular organismal process; GO:0051384 response to glucocorticoid; GO:0010243 response to organonitrogen compound; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0007612 learning; GO:1901698 response to nitrogen compound; GO:0048856 anatomical structure development; GO:0044708 single-organism behavior; GO:0009820 alkaloid metabolic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0006725 cellular aromatic compound metabolic process; GO:0042127 regulation of cell proliferation; GO:1901700 response to oxygen-containing compound; GO:0043279 response to alkaloid; GO:0097164 ammonium ion metabolic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0042493 response to drug; GO:0009991 response to extracellular stimulus; GO:0033993 response to lipid; GO:0030154 cell differentiation; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0046483 heterocycle metabolic process; GO:0050890 cognition; GO:0031960 response to corticosteroid; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0003008 system process; GO:0014016 neuroblast differentiation; GO:0048731 system development; GO:0017144 drug metabolic process; GO:0050804 modulation of synaptic transmission; GO:0006807 nitrogen compound metabolic process; GO:0050783 cocaine metabolic process; GO:0010033 response to organic substance; GO:0007584 response to nutrient; GO:0007611 learning or memory; GO:0044767 single-organism developmental process; GO:0046448 tropane alkaloid metabolic process; GO:0048863 stem cell differentiation; GO:0031667 response to nutrient levels; GO:0009725 response to hormone; GO:0065007 biological regulation; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005641 nuclear envelope lumen; GO:0031974 membrane-enclosed lumen; GO:0031970 organelle envelope lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005788 endoplasmic reticulum lumen; GO:0005635 nuclear envelope; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0072562 blood microparticle; GO:0044432 endoplasmic reticulum part; GO:0031975 envelope; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0070405 ammonium ion binding; GO:0052689 carboxylic ester hydrolase activity; GO:0004104 cholinesterase activity; GO:0033265 choline binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0033218 amide binding; GO:0001540 beta-amyloid binding; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0042277 peptide binding; GO:0005488 binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0043169 cation binding; GO:0003990 acetylcholinesterase activity; GO:0019899 enzyme binding; ","K01050",null,null,"IPR014788; IPR029058; IPR002018; ","\"Acetylcholinesterase, tetramerisation domain; Alpha/Beta hydrolase fold; Carboxylesterase, type B; \"\r"]
["P06280","Alpha-galactosidase A OS=Homo sapiens OX=9606 GN=GLA","GLA",48.766,4.08,4,1,2,1,1.1,0.946,0.944,1.116,0.948,0.96,1.011,0.886,"extracellular\r","GO:0046477 glycosylceramide catabolic process; GO:0045321 leukocyte activation; GO:0045428 regulation of nitric oxide biosynthetic process; GO:0006643 membrane lipid metabolic process; GO:0019377 glycolipid catabolic process; GO:0006672 ceramide metabolic process; GO:0016139 glycoside catabolic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0051001 negative regulation of nitric-oxide synthase activity; GO:0006665 sphingolipid metabolic process; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0006629 lipid metabolic process; GO:0002443 leukocyte mediated immunity; GO:0046466 membrane lipid catabolic process; GO:0031326 regulation of cellular biosynthetic process; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0006664 glycolipid metabolic process; GO:0046514 ceramide catabolic process; GO:0032769 negative regulation of monooxygenase activity; GO:0043603 cellular amide metabolic process; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0005975 carbohydrate metabolic process; GO:0051341 regulation of oxidoreductase activity; GO:0002444 myeloid leukocyte mediated immunity; GO:0006810 transport; GO:0044723 single-organism carbohydrate metabolic process; GO:1901575 organic substance catabolic process; GO:0050789 regulation of biological process; GO:0050790 regulation of catalytic activity; GO:0032768 regulation of monooxygenase activity; GO:0032940 secretion by cell; GO:0044710 single-organism metabolic process; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0043299 leukocyte degranulation; GO:1901657 glycosyl compound metabolic process; GO:0050999 regulation of nitric-oxide synthase activity; GO:2000377 regulation of reactive oxygen species metabolic process; GO:0050794 regulation of cellular process; GO:1903509 liposaccharide metabolic process; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0006687 glycosphingolipid metabolic process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0048523 negative regulation of cellular process; GO:0006677 glycosylceramide metabolic process; GO:0050896 response to stimulus; GO:1904406 negative regulation of nitric oxide metabolic process; GO:0030149 sphingolipid catabolic process; GO:0071704 organic substance metabolic process; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0051354 negative regulation of oxidoreductase activity; GO:0045019 negative regulation of nitric oxide biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009311 oligosaccharide metabolic process; GO:2000378 negative regulation of reactive oxygen species metabolic process; GO:0036230 granulocyte activation; GO:0016137 glycoside metabolic process; GO:0009987 cellular process; GO:0016042 lipid catabolic process; GO:1903426 regulation of reactive oxygen species biosynthetic process; GO:0044712 single-organism catabolic process; GO:0016192 vesicle-mediated transport; GO:1901658 glycosyl compound catabolic process; GO:0006807 nitrogen compound metabolic process; GO:1901136 carbohydrate derivative catabolic process; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:0043312 neutrophil degranulation; GO:0009892 negative regulation of metabolic process; GO:0002263 cell activation involved in immune response; GO:0002366 leukocyte activation involved in immune response; GO:1903427 negative regulation of reactive oxygen species biosynthetic process; GO:0009890 negative regulation of biosynthetic process; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:1901565 organonitrogen compound catabolic process; GO:0001775 cell activation; GO:0044242 cellular lipid catabolic process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0051179 localization; GO:0006955 immune response; GO:0046479 glycosphingolipid catabolic process; GO:0009056 catabolic process; GO:0065007 biological regulation; GO:0006887 exocytosis; GO:1901564 organonitrogen compound metabolic process; ","GO:0034774 secretory granule lumen; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0043202 lysosomal lumen; GO:0042582 azurophil granule; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005102 receptor binding; GO:0046983 protein dimerization activity; GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0016936 galactoside binding; GO:0052692 raffinose alpha-galactosidase activity; GO:0097367 carbohydrate derivative binding; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0015925 galactosidase activity; GO:0005488 binding; GO:0042803 protein homodimerization activity; GO:0016798 hydrolase activity, acting on glycosyl bonds; GO:0004557 alpha-galactosidase activity; ","K01189","GLA; alpha-galactosidase [EC:3.2.1.22]","hsa04142 Lysosome - Homo sapiens (human); hsa00603 Glycosphingolipid biosynthesis - globo and isoglobo series - Homo sapiens (human); hsa00052 Galactose metabolism - Homo sapiens (human); hsa00600 Sphingolipid metabolism - Homo sapiens (human); hsa00561 Glycerolipid metabolism - Homo sapiens (human); ","IPR013785; IPR013780; IPR017853; ","\"Aldolase-type TIM barrel; Glycosyl hydrolase, all-beta; Glycoside hydrolase superfamily; \"\r"]
["P06310","Immunoglobulin kappa variable 2-30 OS=Homo sapiens OX=9606 GN=IGKV2-30","IGKV2-30",13.185,13.993,16.7,2,6,1,0.871,1.047,0.892,1.143,0.98,1.074,1.138,0.149,"extracellular\r","GO:0044700 single organism signaling; GO:0016064 immunoglobulin mediated immune response; GO:0051674 localization of cell; GO:0007166 cell surface receptor signaling pathway; GO:0038094 Fc-gamma receptor signaling pathway; GO:0044699 single-organism process; GO:0006909 phagocytosis; GO:0051234 establishment of localization; GO:0006956 complement activation; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0007154 cell communication; GO:0002250 adaptive immune response; GO:0006958 complement activation, classical pathway; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0044765 single-organism transport; GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0044763 single-organism cellular process; GO:0048870 cell motility; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0050900 leukocyte migration; GO:0048583 regulation of response to stimulus; GO:0002682 regulation of immune system process; GO:0002431 Fc receptor mediated stimulatory signaling pathway; GO:0040011 locomotion; GO:0050794 regulation of cellular process; GO:0016477 cell migration; GO:0002252 immune effector process; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0006959 humoral immune response; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0019724 B cell mediated immunity; GO:1902578 single-organism localization; GO:0002757 immune response-activating signal transduction; GO:0006508 proteolysis; GO:0006898 receptor-mediated endocytosis; GO:0002449 lymphocyte mediated immunity; GO:0038093 Fc receptor signaling pathway; GO:0050778 positive regulation of immune response; GO:0009987 cellular process; GO:0002253 activation of immune response; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0072376 protein activation cascade; GO:0044238 primary metabolic process; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0002684 positive regulation of immune system process; GO:0038095 Fc-epsilon receptor signaling pathway; GO:0006928 movement of cell or subcellular component; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis; GO:0051179 localization; GO:0006955 immune response; GO:0048584 positive regulation of response to stimulus; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0072562 blood microparticle; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0004252 serine-type endopeptidase activity; GO:0004175 endopeptidase activity; GO:0008233 peptidase activity; GO:0003824 catalytic activity; GO:0017171 serine hydrolase activity; GO:0005488 binding; GO:0008236 serine-type peptidase activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0003823 antigen binding; ",{"$nulls":3},"IPR007110; IPR013783; IPR013106; ","Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin V-set domain; \r"]
["P06312","Immunoglobulin kappa variable 4-1 OS=Homo sapiens OX=9606 GN=IGKV4-1","IGKV4-1",13.38,4.5495,12.4,1,1,1,1.097,1.114,0.906,0.892,0.967,1.039,0.93,0.427,"extracellular\r","GO:0044700 single organism signaling; GO:0016064 immunoglobulin mediated immune response; GO:0051674 localization of cell; GO:0007166 cell surface receptor signaling pathway; GO:0038094 Fc-gamma receptor signaling pathway; GO:0044699 single-organism process; GO:0006909 phagocytosis; GO:0051234 establishment of localization; GO:0006956 complement activation; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0007154 cell communication; GO:0002250 adaptive immune response; GO:0006958 complement activation, classical pathway; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0044765 single-organism transport; GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0044763 single-organism cellular process; GO:0048870 cell motility; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0050900 leukocyte migration; GO:0002440 production of molecular mediator of immune response; GO:0048583 regulation of response to stimulus; GO:0002682 regulation of immune system process; GO:0002431 Fc receptor mediated stimulatory signaling pathway; GO:0040011 locomotion; GO:0050794 regulation of cellular process; GO:0016477 cell migration; GO:0002252 immune effector process; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0006959 humoral immune response; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0019724 B cell mediated immunity; GO:1902578 single-organism localization; GO:0002757 immune response-activating signal transduction; GO:0006508 proteolysis; GO:0006898 receptor-mediated endocytosis; GO:0002449 lymphocyte mediated immunity; GO:0038093 Fc receptor signaling pathway; GO:0050778 positive regulation of immune response; GO:0009987 cellular process; GO:0002253 activation of immune response; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0072376 protein activation cascade; GO:0044238 primary metabolic process; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0002377 immunoglobulin production; GO:0002684 positive regulation of immune system process; GO:0038095 Fc-epsilon receptor signaling pathway; GO:0006928 movement of cell or subcellular component; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis; GO:0051179 localization; GO:0006955 immune response; GO:0048584 positive regulation of response to stimulus; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0072562 blood microparticle; GO:0044421 extracellular region part; GO:0005615 extracellular space; GO:0044464 cell part; GO:0071944 cell periphery; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; ","GO:0004252 serine-type endopeptidase activity; GO:0004175 endopeptidase activity; GO:0008233 peptidase activity; GO:0003824 catalytic activity; GO:0017171 serine hydrolase activity; GO:0005488 binding; GO:0008236 serine-type peptidase activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0003823 antigen binding; ",{"$nulls":3},"IPR007110; IPR013783; IPR003599; IPR013106; ","Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin subtype; Immunoglobulin V-set domain; \r"]
["P06454","Prothymosin alpha OS=Homo sapiens OX=9606 GN=PTMA","PTMA",12.203,13.735,12.6,1,3,1,0.854,0.846,0.86,1.114,1.171,1.128,1.333,5.64e-05,"cytoplasm\r","GO:0018130 heterocycle biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0097659 nucleic acid-templated transcription; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0009058 biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044237 cellular metabolic process; GO:0044249 cellular biosynthetic process; GO:0071704 organic substance metabolic process; GO:0016070 RNA metabolic process; GO:0008152 metabolic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0090304 nucleic acid metabolic process; GO:0046483 heterocycle metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006351 transcription, DNA-templated; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0010467 gene expression; GO:0043170 macromolecule metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:1901362 organic cyclic compound biosynthetic process; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0005488 binding; "]
["P06493","Cyclin-dependent kinase 1 OS=Homo sapiens OX=9606 GN=CDK1","CDK1",34.095,7.4024,10.4,3,4,2,0.746,0.756,0.809,1.331,1.151,1.19,1.589,0.0008,"cytoplasm\r",{"$cut":{"chars":22295,"head":"GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:1902807 negative regulation of cell cycle G1/S phase transition; GO:0010941 regulation of cell death; GO:0014013 regulation of gliogenesis; GO:0022414 reproductive process; GO:0051443 positive regulation of ubiquitin-protein transferase activity; GO:0009891 positive regulation of biosynthetic process; GO:0044237 cellular metabolic process; GO:0010564 regulation of cell cycle process; GO:0044782 cilium organization; GO:0045927 positive regulation of growth; GO:0072431 signal transduction involved in mitotic G1 DNA damage checkpoint; GO:1902403 signal transduction involved in mitotic DNA integrity checkpoint; GO:0071900 regulation of protein serine/threonine kinase activity; GO:1903364 positive regulation of cellular protein catabolic process; GO:0008152 metabolic process; GO:0065003 macromolecular complex assembly; GO:0048308 organelle inheritance; GO:0044093 positive regulation of molecular function; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0044770 cell cycle phase transition; GO:0090068 positive regulation of cell cycle process; GO:0055013 cardiac muscle cell development; GO:0007077 mitotic nuclear envelope disassembly; GO:0042325 regulation of phosphorylation; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0055025 positive regulation of cardiac muscle tissue development; GO:0044773 mitotic DNA damage checkpoint; GO:0051054 positive regulation of DNA metabolic process; GO:0080090 regulation of primary metabolic process; GO:0060537 muscle tissue development; GO:0048699 generation of neurons; GO:0010972 negative regulation of G2/M transition of mitotic cell cycle; GO:2000134 negative regulation of G1/S transition of mitotic cell cycle; GO:0044763 single-organism cellular process; GO:0048870 cell motility; GO:0043086 negative regulation of catalytic activity; GO:0051704 multi-organism process; GO:1901575 organic substance catabolic process; GO:0000226 microtubule cytoskeleton organization; GO:0010243 response to organonitrogen compound; GO:0014823 response to activity; GO:0045931 positive regulation of mitotic cell cycle; GO:0007030 Golgi organization; GO:1902400 intracellular signal transduction involved in G1 DNA damage checkpoint; GO:0030163 protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:1901698 response to nitrogen compound; GO:0044260 cellular macromolecule metabolic process; GO:0051223 regulation of protein transport; GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:0060548 negative regulation of cell death; GO:1901863 positive regulation of muscle tissue development; GO:0042307 positive regulation of protein import into nucleus; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0030855 epithelial cell differentiation; GO:0000003 reproduction; GO:0055001 muscle cell development; GO:0072359 circulatory system development; GO:0016310 phosphorylation; GO:0044707 single-multicellular organism process; GO:0006259 DNA metabolic process; GO:0016570 histone modification; GO:1901700 response to oxygen-containing compound; GO:0051297 centrosome organization; GO:0033158 regulation of protein import into nucleus, translocation; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0042493 response to drug; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0051081 nuclear envelope disassembly; GO:1902402 signal transduction involved in mitotic DNA damage checkpoint; GO:0009889 regulation of biosynthetic process; GO:0044819 mitotic G1/S transition checkpoint; GO:0009896 positive regulation of catabolic process; GO:0061061 muscle structure development; GO:0044248 cellular catabolic process; GO:0042176 regulation of protein catabolic process; GO:0034613 cellular protein localization; GO:0016567 protein ubiquitination; GO:0006950 "}},"GO:0016020 membrane; GO:0000784 nuclear chromosome, telomeric region; GO:0000781 chromosome, telomeric region; GO:0044421 extracellular region part; GO:0005874 microtubule; GO:0061695 transferase complex, transferring phosphorus-containing groups; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:1902554 serine/threonine protein kinase complex; GO:0099080 supramolecular complex; GO:0005623 cell; GO:1902911 protein kinase complex; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0072686 mitotic spindle; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:1902494 catalytic complex; GO:0005815 microtubule organizing center; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0044454 nuclear chromosome part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0030496 midbody; GO:0031981 nuclear lumen; GO:0000307 cyclin-dependent protein kinase holoenzyme complex; GO:1990234 transferase complex; GO:0005829 cytosol; GO:0005819 spindle; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0099081 supramolecular polymer; GO:0005876 spindle microtubule; GO:0098687 chromosomal region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005813 centrosome; GO:0000228 nuclear chromosome; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0005515 protein binding; GO:0004693 cyclin-dependent protein serine/threonine kinase activity; GO:0003682 chromatin binding; GO:0004672 protein kinase activity; GO:0030544 Hsp70 protein binding; GO:0030332 cyclin binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016301 kinase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0031072 heat shock protein binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity; GO:0035173 histone kinase activity; GO:0000166 nucleotide binding; GO:0097472 cyclin-dependent protein kinase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0004674 protein serine/threonine kinase activity; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K02087","CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]","hsa04218 Cellular senescence - Homo sapiens (human); hsa04540 Gap junction - Homo sapiens (human); hsa05168 Herpes simplex infection - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); hsa04115 p53 signaling pathway - Homo sapiens (human); hsa05203 Viral carcinogenesis - Homo sapiens (human); hsa04110 Cell cycle - Homo sapiens (human); hsa04914 Progesterone-mediated oocyte maturation - Homo sapiens (human); hsa04114 Oocyte meiosis - Homo sapiens (human); ","IPR000719; IPR011009; ","Protein kinase domain; Protein kinase-like domain; \r"]
["P06576","ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B","ATP5F1B",56.559,269.3,45.4,17,61,17,0.987,0.996,1.086,0.996,0.972,0.982,0.961,0.284,"mitochondria\r","GO:0001649 osteoblast differentiation; GO:0065008 regulation of biological quality; GO:0009116 nucleoside metabolic process; GO:0030641 regulation of cellular pH; GO:0030004 cellular monovalent inorganic cation homeostasis; GO:0009163 nucleoside biosynthetic process; GO:0046129 purine ribonucleoside biosynthetic process; GO:0044237 cellular metabolic process; GO:0046390 ribose phosphate biosynthetic process; GO:0001525 angiogenesis; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:1901137 carbohydrate derivative biosynthetic process; GO:0019693 ribose phosphate metabolic process; GO:0009145 purine nucleoside triphosphate biosynthetic process; GO:0044765 single-organism transport; GO:0018130 heterocycle biosynthetic process; GO:0009206 purine ribonucleoside triphosphate biosynthetic process; GO:0001503 ossification; GO:0044281 small molecule metabolic process; GO:0006754 ATP biosynthetic process; GO:0044763 single-organism cellular process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0048870 cell motility; GO:0032501 multicellular organismal process; GO:0009168 purine ribonucleoside monophosphate biosynthetic process; GO:0090407 organophosphate biosynthetic process; GO:0006810 transport; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0015986 ATP synthesis coupled proton transport; GO:0009126 purine nucleoside monophosphate metabolic process; GO:0006164 purine nucleotide biosynthetic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0098662 inorganic cation transmembrane transport; GO:0009201 ribonucleoside triphosphate biosynthetic process; GO:0050794 regulation of cellular process; GO:0072359 circulatory system development; GO:0044707 single-multicellular organism process; GO:0046907 intracellular transport; GO:0007162 negative regulation of cell adhesion; GO:0034220 ion transmembrane transport; GO:0006885 regulation of pH; GO:0042776 mitochondrial ATP synthesis coupled proton transport; GO:0009259 ribonucleotide metabolic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0009653 anatomical structure morphogenesis; GO:0046483 heterocycle metabolic process; GO:1902578 single-organism localization; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:1902580 single-organism cellular localization; GO:0007275 multicellular organism development; GO:0099131 ATP hydrolysis coupled ion transmembrane transport; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0009119 ribonucleoside metabolic process; GO:0048878 chemical homeostasis; GO:0044711 single-organism biosynthetic process; GO:0048731 system development; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0072358 cardiovascular system development; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0042455 ribonucleoside biosynthetic process; GO:1901576 organic substance biosynthetic process; GO:0030155 regulation of cell adhesion; GO:0006163 purine nucleotide metabolic process; GO:0055085 transmembrane transport; GO:0006873 cellular ion homeostasis; GO:0051453 regulation of intracellular pH; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0006811 ion transport; GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration; GO:0009260 ribonucleotide biosynthetic process; GO:0006928 movement of cell or subcellular component; GO:0019637 organophosphate metabolic process; GO:0051179 localization; GO:0015672 monovalent inorganic cation transport; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0051674 localization of cell; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0001568 blood vessel development; GO:0090662 ATP hydrolysis coupled transmembrane transport; GO:0048869 cellular developmental process; GO:0006839 mitochondrial transport; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0009156 ribonucleoside monophosphate biosynthetic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0051649 establishment of localization in cell; GO:0006753 nucleoside phosphate metabolic process; GO:0007005 mitochondrion organization; GO:0048514 blood vessel morphogenesis; GO:0006929 substrate-dependent cell migration; GO:0006629 lipid metabolic process; GO:0032502 developmental process; GO:0098655 cation transmembrane transport; GO:0050801 ion homeostasis; GO:0098771 inorganic ion homeostasis; GO:0019725 cellular homeostasis; GO:1901360 organic cyclic compound metabolic process; GO:0001944 vasculature development; GO:0015985 energy coupled proton transport, down electrochemical gradient; GO:0009199 ribonucleoside triphosphate metabolic process; GO:1902582 single-organism intracellular transport; GO:0042451 purine nucleoside biosynthetic process; GO:0050789 regulation of biological process; GO:0072522 purine-containing compound biosynthetic process; GO:0040011 locomotion; GO:1901657 glycosyl compound metabolic process; GO:0048856 anatomical structure development; GO:0016477 cell migration; GO:0016043 cellular component organization; GO:0009165 nucleotide biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0030003 cellular cation homeostasis; GO:0009142 nucleoside triphosphate biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0055082 cellular chemical homeostasis; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:0055080 cation homeostasis; GO:0006812 cation transport; GO:1990542 mitochondrial transmembrane transport; GO:1902600 hydrogen ion transmembrane transport; GO:0034641 cellular nitrogen compound metabolic process; GO:0099132 ATP hydrolysis coupled cation transmembrane transport; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0009987 cellular process; GO:0046034 ATP metabolic process; GO:0055067 monovalent inorganic cation homeostasis; GO:0009124 nucleoside monophosphate biosynthetic process; GO:0098660 inorganic ion transmembrane transport; GO:0009127 purine nucleoside monophosphate biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0015992 proton transport; GO:0006818 hydrogen transport; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0046128 purine ribonucleoside metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0009152 purine ribonucleotide biosynthetic process; GO:0044767 single-organism developmental process; GO:1901659 glycosyl compound biosynthetic process; GO:0009150 purine ribonucleotide metabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0005754 mitochondrial proton-transporting ATP synthase, catalytic core; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0098798 mitochondrial protein complex; GO:0005623 cell; GO:0044455 mitochondrial membrane part; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0005740 mitochondrial envelope; GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1); GO:0070013 intracellular organelle lumen; GO:0043209 myelin sheath; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0043233 organelle lumen; GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0042645 mitochondrial nucleoid; GO:0044429 mitochondrial part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0005576 extracellular region; GO:0045259 proton-transporting ATP synthase complex; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0031012 extracellular matrix; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005753 mitochondrial proton-transporting ATP synthase complex; GO:0031975 envelope; GO:0016469 proton-transporting two-sector ATPase complex; GO:0045267 proton-transporting ATP synthase, catalytic core; GO:0009986 cell surface; GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain; GO:0043234 protein complex; GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1); GO:0009295 nucleoid; GO:0043230 extracellular organelle; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0042625 ATPase coupled ion transmembrane transporter activity; GO:1901265 nucleoside phosphate binding; GO:0005102 receptor binding; GO:0015399 primary active transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism; GO:0015077 monovalent inorganic cation transmembrane transporter activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0015078 hydrogen ion transmembrane transporter activity; GO:0042288 MHC class I protein binding; GO:0022891 substrate-specific transmembrane transporter activity; GO:0046933 proton-transporting ATP synthase activity, rotational mechanism; GO:0016887 ATPase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0019829 cation-transporting ATPase activity; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0043492 ATPase activity, coupled to movement of substances; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0042287 MHC protein binding; GO:0036442 hydrogen-exporting ATPase activity; GO:0043168 anion binding; GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0022890 inorganic cation transmembrane transporter activity; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005215 transporter activity; GO:0022804 active transmembrane transporter activity; GO:0005524 ATP binding; GO:0015075 ion transmembrane transporter activity; GO:0022853 active ion transmembrane transporter activity; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0046961 proton-transporting ATPase activity, rotational mechanism; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity; GO:0042626 ATPase activity, coupled to transmembrane movement of substances; GO:0042623 ATPase activity, coupled; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0008324 cation transmembrane transporter activity; GO:0036094 small molecule binding; GO:0022857 transmembrane transporter activity; ","K02133","ATPeF1B; F-type H+-transporting ATPase subunit beta [EC:3.6.3.14]","hsa05010 Alzheimer's disease - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); ","IPR004100; IPR003593; IPR000194; IPR027417; IPR024034; ","\"ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain; AAA+ ATPase domain; ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain; P-loop containing nucleoside triphosphate hydrolase; ATPase, F1/V1 complex, beta subunit, C-terminal; \"\r"]
["P06681","Complement C2 OS=Homo sapiens OX=9606 GN=C2","C2",83.267,74.645,19.4,13,20,13,1.014,0.955,0.979,1.101,1.053,0.955,1.055,0.319,"extracellular\r","GO:0060627 regulation of vesicle-mediated transport; GO:2000425 regulation of apoptotic cell clearance; GO:0016064 immunoglobulin mediated immune response; GO:0031347 regulation of defense response; GO:0051130 positive regulation of cellular component organization; GO:0006956 complement activation; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0032879 regulation of localization; GO:0002250 adaptive immune response; GO:0006958 complement activation, classical pathway; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0050764 regulation of phagocytosis; GO:0002697 regulation of immune effector process; GO:0010468 regulation of gene expression; GO:0002443 leukocyte mediated immunity; GO:0080090 regulation of primary metabolic process; GO:0048522 positive regulation of cellular process; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0051050 positive regulation of transport; GO:0050776 regulation of immune response; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0048583 regulation of response to stimulus; GO:0019222 regulation of metabolic process; GO:0002682 regulation of immune system process; GO:0006952 defense response; GO:1903317 regulation of protein maturation; GO:0050794 regulation of cellular process; GO:0030449 regulation of complement activation; GO:2000257 regulation of protein activation cascade; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0045807 positive regulation of endocytosis; GO:0002920 regulation of humoral immune response; GO:0002673 regulation of acute inflammatory response; GO:0006959 humoral immune response; GO:0080134 regulation of response to stress; GO:2000427 positive regulation of apoptotic cell clearance; GO:0050896 response to stimulus; GO:0045087 innate immune response; GO:0071704 organic substance metabolic process; GO:0019724 B cell mediated immunity; GO:0009991 response to extracellular stimulus; GO:0006508 proteolysis; GO:0002449 lymphocyte mediated immunity; GO:0050778 positive regulation of immune response; GO:0002253 activation of immune response; GO:0030100 regulation of endocytosis; GO:0006950 response to stress; GO:0051049 regulation of transport; GO:0050766 positive regulation of phagocytosis; GO:0002376 immune system process; GO:0032101 regulation of response to external stimulus; GO:0072376 protein activation cascade; GO:0030162 regulation of proteolysis; GO:0007584 response to nutrient; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0051246 regulation of protein metabolic process; GO:0002684 positive regulation of immune system process; GO:0050727 regulation of inflammatory response; GO:0070613 regulation of protein processing; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0051128 regulation of cellular component organization; GO:0031667 response to nutrient levels; GO:0006955 immune response; GO:0048584 positive regulation of response to stimulus; GO:0065007 biological regulation; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:0004252 serine-type endopeptidase activity; GO:0004175 endopeptidase activity; GO:0008233 peptidase activity; GO:0017171 serine hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0008236 serine-type peptidase activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0016787 hydrolase activity; GO:0005515 protein binding; ","K01332","C2; complement component 2 [EC:3.4.21.43]","hsa05322 Systemic lupus erythematosus - Homo sapiens (human); hsa05133 Pertussis - Homo sapiens (human); hsa04610 Complement and coagulation cascades - Homo sapiens (human); hsa05150 Staphylococcus aureus infection - Homo sapiens (human); ","IPR009003; IPR000436; IPR001254; IPR002035; ","\"Peptidase S1, PA clan; Sushi/SCR/CCP domain; Serine proteases, trypsin domain; von Willebrand factor, type A; \"\r"]
["P06702","Protein S100-A9 OS=Homo sapiens OX=9606 GN=S100A9","S100A9",13.242,168.29,71.1,10,99,10,0.366,0.415,0.407,1.556,1.574,1.501,3.898,2.59e-06,"cytoplasm\r","GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0010608 posttranscriptional regulation of gene expression; GO:0098542 defense response to other organism; GO:0002793 positive regulation of peptide secretion; GO:0031347 regulation of defense response; GO:0006914 autophagy; GO:0044237 cellular metabolic process; GO:0045927 positive regulation of growth; GO:0009607 response to biotic stimulus; GO:0001558 regulation of cell growth; GO:0008152 metabolic process; GO:0044093 positive regulation of molecular function; GO:0055065 metal ion homeostasis; GO:0051493 regulation of cytoskeleton organization; GO:0098869 cellular oxidant detoxification; GO:0030194 positive regulation of blood coagulation; GO:0052548 regulation of endopeptidase activity; GO:0051716 cellular response to stimulus; GO:0010950 positive regulation of endopeptidase activity; GO:0030307 positive regulation of cell growth; GO:0050729 positive regulation of inflammatory response; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0048870 cell motility; GO:0006935 chemotaxis; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0031532 actin cytoskeleton reorganization; GO:0051092 positive regulation of NF-kappaB transcription factor activity; GO:0042063 gliogenesis; GO:0007267 cell-cell signaling; GO:1900048 positive regulation of hemostasis; GO:0048583 regulation of response to stimulus; GO:0098602 single organism cell adhesion; GO:0044260 cellular macromolecule metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0044707 single-multicellular organism process; GO:2001056 positive regulation of cysteine-type endopeptidase activity; GO:0097530 granulocyte migration; GO:1990748 cellular detoxification; GO:0051345 positive regulation of hydrolase activity; GO:0009889 regulation of biosynthetic process; GO:0018119 peptidyl-cysteine S-nitrosylation; GO:0044248 cellular catabolic process; GO:0032602 chemokine production; GO:0050778 positive regulation of immune response; GO:0048878 chemical homeostasis; GO:0006950 response to stress; GO:0032101 regulation of response to external stimulus; GO:0002376 immune system process; GO:0002263 cell activation involved in immune response; GO:0034248 regulation of cellular amide metabolic process; GO:0045055 regulated exocytosis; GO:0006882 cellular zinc ion homeostasis; GO:0061041 regulation of wound healing; GO:0006996 organelle organization; GO:0001816 cytokine production; GO:0031325 positive regulation of cellular metabolic process; GO:0006955 immune response; GO:0043412 macromolecule modification; GO:0070488 neutrophil aggregation; GO:1903034 regulation of response to wounding; GO:0051674 localization of cell; GO:0023051 regulation of signaling; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0051046 regulation of secretion; GO:2001141 regulation of RNA biosynthetic process; GO:0016337 single organismal cell-cell adhesion; GO:0007165 signal transduction; GO:0071621 granulocyte chemotaxis; GO:0009893 positive regulation of metabolic process; GO:0006915 apoptotic process; GO:1900046 regulation of hemostasis; GO:0002221 pattern recognition receptor signaling pathway; GO:0031326 regulation of cellular biosynthetic process; GO:2000116 regulation of cysteine-type endopeptidase activity; GO:0009636 response to toxic substance; GO:0098609 cell-cell adhesion; GO:0098771 inorganic ion homeostasis; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0002444 myeloid leukocyte mediated immunity; GO:0010942 positive regulation of cell death; GO:0030593 neutrophil chemotaxis; GO:0032940 secretion by cell; GO:0006954 inflammatory response; GO:0065009 regulation of molecular function; GO:0006952 defense response; GO:0036211 protein modification process; GO:0098754 detoxification; GO:0016043 cellular component organization; GO:0016477 cell migration; GO:0040008 regulation of growth; GO:0060255 regulation of macromolecule metabolic process; GO:0043065 positive regulation of apoptotic process; GO:0051707 response to other organism; GO:0045087 innate immune response; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:0045862 positive regulation of proteolysis; GO:0055080 cation homeostasis; GO:0023056 positive regulation of signaling; GO:2001235 positive regulation of apoptotic signaling pathway; GO:0002757 immune response-activating signal transduction; GO:0010647 positive regulation of cell communication; GO:0051235 maintenance of location; GO:0006355 regulation of transcription, DNA-templated; GO:0050878 regulation of body fluid levels; GO:0042742 defense response to bacterium; GO:0051049 regulation of transport; GO:0033043 regulation of organelle organization; GO:0050820 positive regulation of coagulation; GO:0043085 positive regulation of catalytic activity; GO:0050832 defense response to fungus; GO:0002366 leukocyte activation involved in immune response; GO:0018193 peptidyl-amino acid modification; GO:0010001 glial cell differentiation; GO:0042119 neutrophil activation; GO:0030595 leukocyte chemotaxis; GO:0008219 cell death; GO:0002684 positive regulation of immune system process; GO:0050727 regulation of inflammatory response; GO:0009056 catabolic process; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0045321 leukocyte activation; GO:0070486 leukocyte aggregation; GO:0022610 biological adhesion; GO:1903729 regulation of plasma membrane organization; GO:0009605 response to external stimulus; GO:0030036 actin cytoskeleton organization; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0007155 cell adhesion; GO:0035606 peptidyl-cysteine S-trans-nitrosylation; GO:0090303 positive regulation of wound healing; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0007399 nervous system development; GO:0002443 leukocyte mediated immunity; GO:0009620 response to fungus; GO:0002758 innate immune response-activating signal transduction; GO:0019730 antimicrobial humoral response; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0046916 cellular transition metal ion homeostasis; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050900 leukocyte migration; GO:0051336 regulation of hydrolase activity; GO:0007417 central nervous system development; GO:0018198 peptidyl-cysteine modification; GO:0050790 regulation of catalytic activity; GO:0051090 regulation of sequence-specific DNA binding transcription factor activity; GO:0010604 positive regulation of macromolecule metabolic process; GO:2001244 positive regulation of intrinsic apoptotic signaling pathway; GO:0006464 cellular protein modification process; GO:0042330 taxis; GO:0002682 regulation of immune system process; GO:0043068 positive regulation of programmed cell death; GO:0010952 positive regulation of peptidase activity; GO:0051047 positive regulation of secretion; GO:1903036 positive regulation of response to wounding; GO:0050794 regulation of cellular process; GO:0055076 transition metal ion homeostasis; GO:0002283 neutrophil activation involved in immune response; GO:0014002 astrocyte development; GO:0044267 cellular protein metabolic process; GO:0043067 regulation of programmed cell death; GO:0030193 regulation of blood coagulation; GO:0080134 regulation of response to stress; GO:0060326 cell chemotaxis; GO:0051239 regulation of multicellular organismal process; GO:0031349 positive regulation of defense response; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0051171 regulation of nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0009966 regulation of signal transduction; GO:0017014 protein nitrosylation; GO:0009617 response to bacterium; GO:0090087 regulation of peptide transport; GO:0002253 activation of immune response; GO:1902531 regulation of intracellular signal transduction; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0002523 leukocyte migration involved in inflammatory response; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0051247 positive regulation of protein metabolic process; GO:0006873 cellular ion homeostasis; GO:0030029 actin filament-based process; GO:0006928 movement of cell or subcellular component; GO:0001775 cell activation; GO:0012501 programmed cell death; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0006887 exocytosis; GO:0072503 cellular divalent inorganic cation homeostasis; GO:1902533 positive regulation of intracellular signal transduction; GO:0022008 neurogenesis; GO:0055069 zinc ion homeostasis; GO:0051234 establishment of localization; GO:1990266 neutrophil migration; GO:2001233 regulation of apoptotic signaling pathway; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0097529 myeloid leukocyte migration; GO:0045088 regulation of innate immune response; GO:0032103 positive regulation of response to external stimulus; GO:0045113 regulation of integrin biosynthetic process; GO:0070887 cellular response to chemical stimulus; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0050801 ion homeostasis; GO:0002446 neutrophil mediated immunity; GO:0048522 positive regulation of cellular process; GO:0019725 cellular homeostasis; GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity; GO:0051050 positive regulation of transport; GO:1902589 single-organism organelle organization; GO:0032268 regulation of cellular protein metabolic process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0002224 toll-like receptor signaling pathway; GO:0021782 glial cell development; GO:0019222 regulation of metabolic process; GO:0048708 astrocyte differentiation; GO:0040011 locomotion; GO:0043299 leukocyte degranulation; GO:0052547 regulation of peptidase activity; GO:0048856 anatomical structure development; GO:0072507 divalent inorganic cation homeostasis; GO:0051238 sequestering of metal ion; GO:0007159 leukocyte cell-cell adhesion; GO:0002218 activation of innate immune response; GO:0002252 immune effector process; GO:0030003 cellular cation homeostasis; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0006959 humoral immune response; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0055082 cellular chemical homeostasis; GO:0002791 regulation of peptide secretion; GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0045089 positive regulation of innate immune response; GO:0032119 sequestering of zinc ion; GO:0010556 regulation of macromolecule biosynthetic process; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0050818 regulation of coagulation; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0006417 regulation of translation; GO:2001242 regulation of intrinsic apoptotic signaling pathway; GO:0006875 cellular metal ion homeostasis; GO:0009967 positive regulation of signal transduction; GO:0051128 regulation of cellular component organization; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0034774 secretory granule lumen; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0031012 extracellular matrix; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0036041 long-chain fatty acid binding; GO:0005102 receptor binding; GO:0050544 arachidonic acid binding; GO:0043167 ion binding; GO:0050543 icosatetraenoic acid binding; GO:0016209 antioxidant activity; GO:0035325 Toll-like receptor binding; GO:0015631 tubulin binding; GO:0043177 organic acid binding; GO:0005515 protein binding; GO:0008270 zinc ion binding; GO:0033293 monocarboxylic acid binding; GO:0004871 signal transducer activity; GO:0008092 cytoskeletal protein binding; GO:0050786 RAGE receptor binding; GO:0031406 carboxylic acid binding; GO:0046914 transition metal ion binding; GO:0008017 microtubule binding; GO:0005488 binding; GO:0008289 lipid binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0043168 anion binding; GO:0005509 calcium ion binding; GO:0005504 fatty acid binding; GO:0050542 icosanoid binding; GO:0035662 Toll-like receptor 4 binding; GO:1901567 fatty acid derivative binding; GO:0036094 small molecule binding; ","K21128","S100A9; protein S100-A9","hsa04657 IL-17 signaling pathway - Homo sapiens (human); ","IPR002048; IPR011992; IPR013787; ","\"EF-hand domain; EF-hand domain pair; S100/CaBP-9k-type, calcium binding, subdomain; \"\r"]
["P06703","Protein S100-A6 OS=Homo sapiens OX=9606 GN=S100A6","S100A6",10.18,12.62,34.4,5,16,5,1.124,1.043,1.093,0.915,0.9,0.886,0.829,0.00138,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0034220 ion transmembrane transport; GO:0042127 regulation of cell proliferation; GO:0048869 cellular developmental process; GO:0048666 neuron development; GO:0032989 cellular component morphogenesis; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0000904 cell morphogenesis involved in differentiation; GO:0051234 establishment of localization; GO:0048145 regulation of fibroblast proliferation; GO:0009653 anatomical structure morphogenesis; GO:0030154 cell differentiation; GO:0007165 signal transduction; GO:0048146 positive regulation of fibroblast proliferation; GO:0007154 cell communication; GO:0032990 cell part morphogenesis; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0007409 axonogenesis; GO:0048858 cell projection morphogenesis; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0048731 system development; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0048812 neuron projection morphogenesis; GO:0031175 neuron projection development; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0048518 positive regulation of biological process; GO:0000902 cell morphogenesis; GO:0006810 transport; GO:0030182 neuron differentiation; GO:0061564 axon development; GO:0055085 transmembrane transport; GO:0050789 regulation of biological process; GO:0030030 cell projection organization; GO:0044767 single-organism developmental process; GO:0006811 ion transport; GO:0051179 localization; GO:0048856 anatomical structure development; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:0008284 positive regulation of cell proliferation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0019898 extrinsic component of membrane; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0031234 extrinsic component of cytoplasmic side of plasma membrane; GO:0005623 cell; GO:0009898 cytoplasmic side of plasma membrane; GO:0098562 cytoplasmic side of membrane; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0043227 membrane-bounded organelle; GO:0098552 side of membrane; GO:0031252 cell leading edge; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0005635 nuclear envelope; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0019897 extrinsic component of plasma membrane; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0031975 envelope; GO:0001726 ruffle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0015075 ion transmembrane transporter activity; GO:0046983 protein dimerization activity; GO:0043167 ion binding; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0005523 tropomyosin binding; GO:0008270 zinc ion binding; GO:0048306 calcium-dependent protein binding; GO:0022891 substrate-specific transmembrane transporter activity; GO:0008092 cytoskeletal protein binding; GO:0042802 identical protein binding; GO:0046914 transition metal ion binding; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0044548 S100 protein binding; GO:0005509 calcium ion binding; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; ",{"$nulls":3},"IPR002048; IPR011992; IPR013787; ","\"EF-hand domain; EF-hand domain pair; S100/CaBP-9k-type, calcium binding, subdomain; \"\r"]
["P06727","Apolipoprotein A-IV OS=Homo sapiens OX=9606 GN=APOA4","APOA4",45.398,202.99,62.4,25,47,25,1.028,1.073,1.003,0.961,0.943,0.983,0.93,0.0352,"extracellular\r","GO:0044085 cellular component biogenesis; GO:0006801 superoxide metabolic process; GO:0065008 regulation of biological quality; GO:0007586 digestion; GO:0032371 regulation of sterol transport; GO:0006066 alcohol metabolic process; GO:0009891 positive regulation of biosynthetic process; GO:0070328 triglyceride homeostasis; GO:0044255 cellular lipid metabolic process; GO:0019216 regulation of lipid metabolic process; GO:0044237 cellular metabolic process; GO:0042157 lipoprotein metabolic process; GO:0008610 lipid biosynthetic process; GO:0019430 removal of superoxide radicals; GO:0022610 biological adhesion; GO:0030300 regulation of intestinal cholesterol absorption; GO:0008152 metabolic process; GO:0065003 macromolecular complex assembly; GO:0050996 positive regulation of lipid catabolic process; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0071825 protein-lipid complex subunit organization; GO:0044057 regulation of system process; GO:0007155 cell adhesion; GO:0098869 cellular oxidant detoxification; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044240 multicellular organismal lipid catabolic process; GO:0055088 lipid homeostasis; GO:0046889 positive regulation of lipid biosynthetic process; GO:0044765 single-organism transport; GO:0007399 nervous system development; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0006869 lipid transport; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0060191 regulation of lipase activity; GO:0044281 small molecule metabolic process; GO:0000302 response to reactive oxygen species; GO:0008202 steroid metabolic process; GO:0044763 single-organism cellular process; GO:1901617 organic hydroxy compound biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0002385 mucosal immune response; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0034443 negative regulation of lipoprotein oxidation; GO:0035634 response to stilbenoid; GO:0034377 plasma lipoprotein particle assembly; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0046890 regulation of lipid biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0098602 single organism cell adhesion; GO:0042304 regulation of fatty acid biosynthetic process; GO:0090208 positive regulation of triglyceride metabolic process; GO:0016101 diterpenoid metabolic process; GO:0034444 regulation of plasma lipoprotein particle oxidation; GO:0050994 regulation of lipid catabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0010873 positive regulation of cholesterol esterification; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0044707 single-multicellular organism process; GO:0010896 regulation of triglyceride catabolic process; GO:1901615 organic hydroxy compound metabolic process; GO:1902653 secondary alcohol biosynthetic process; GO:1901700 response to oxygen-containing compound; GO:0044267 cellular protein metabolic process; GO:0034372 very-low-density lipoprotein particle remodeling; GO:0097164 ammonium ion metabolic process; GO:0019218 regulation of steroid metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0045940 positive regulation of steroid metabolic process; GO:0016125 sterol metabolic process; GO:0051239 regulation of multicellular organismal process; GO:0016126 sterol biosynthetic process; GO:0034370 triglyceride-rich lipoprotein particle remodeling; GO:0042743 hydrogen peroxide metabolic process; GO:1990748 cellular detoxification; GO:1902578 single-organism localization; GO:0051345 positive regulation of hydrolase activity; GO:0009889 regulation of biosynthetic process; GO:0061365 positive regulation of triglyceride lipase activity; GO:0009896 positive regulation of catabolic process; GO:0051004 regulation of lipoprotein lipase activity; GO:0044248 cellular catabolic process; GO:0034369 plasma lipoprotein particle remodeling; GO:0007275 multicellular organism development; GO:0090207 regulation of triglyceride metabolic process; GO:0033700 phospholipid efflux; GO:0050748 negative regulation of lipoprotein metabolic process; GO:0051006 positive regulation of lipoprotein lipase activity; GO:0042744 hydrogen peroxide catabolic process; GO:0050746 regulation of lipoprotein metabolic process; GO:0048878 chemical homeostasis; GO:0010898 positive regulation of triglyceride catabolic process; GO:0016042 lipid catabolic process; GO:0006720 isoprenoid metabolic process; GO:0008203 cholesterol metabolic process; GO:0044711 single-organism biosynthetic process; GO:0006950 response to stress; GO:0010872 regulation of cholesterol esterification; GO:0048731 system development; GO:0046165 alcohol biosynthetic process; GO:0002376 immune system process; GO:0010876 lipid localization; GO:0071702 organic substance transport; GO:0015914 phospholipid transport; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0019217 regulation of fatty acid metabolic process; GO:0006694 steroid biosynthetic process; GO:0030182 neuron differentiation; GO:0006793 phosphorus metabolic process; GO:0006811 ion transport; GO:0031325 positive regulation of cellular metabolic process; GO:0044283 small molecule biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0002251 organ or tissue specific immune response; GO:0034375 high-density lipoprotein particle remodeling; GO:0006644 phospholipid metabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0006955 immune response; GO:0051179 localization; GO:0034378 chylomicron assembly; GO:0045923 positive regulation of fatty acid metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0034367 macromolecular complex remodeling; GO:0046470 phosphatidylcholine metabolic process; GO:0015850 organic hydroxy compound transport; GO:0000303 response to superoxide; GO:0046486 glycerolipid metabolic process; GO:0033194 response to hydroperoxide; GO:0030301 cholesterol transport; GO:0033344 cholesterol efflux; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0031331 positive regulation of cellular catabolic process; GO:0044236 multicellular organism metabolic process; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:1904478 regulation of intestinal absorption; GO:0034442 regulation of lipoprotein oxidation; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0044241 lipid digestion; GO:0016337 single organismal cell-cell adhesion; GO:0022607 cellular component assembly; GO:0009893 positive regulation of metabolic process; GO:0006979 response to oxidative stress; GO:0006650 glycerophospholipid metabolic process; GO:0006982 response to lipid hydroperoxide; GO:0034599 cellular response to oxidative stress; GO:0010035 response to inorganic substance; GO:0033036 macromolecule localization; GO:0042158 lipoprotein biosynthetic process; GO:0043691 reverse cholesterol transport; GO:0070887 cellular response to chemical stimulus; GO:0006629 lipid metabolic process; GO:0032502 developmental process; GO:0071827 plasma lipoprotein particle organization; GO:0034614 cellular response to reactive oxygen species; GO:0031326 regulation of cellular biosynthetic process; GO:0071450 cellular response to oxygen radical; GO:0009636 response to toxic substance; GO:0098609 cell-cell adhesion; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0031102 neuron projection regeneration; GO:0010605 negative regulation of macromolecule metabolic process; GO:0032374 regulation of cholesterol transport; GO:0010565 regulation of cellular ketone metabolic process; GO:0060193 positive regulation of lipase activity; GO:0015748 organophosphate ester transport; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0030030 cell projection organization; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0000305 response to oxygen radical; GO:0045723 positive regulation of fatty acid biosynthetic process; GO:0065005 protein-lipid complex assembly; GO:0006952 defense response; GO:0048856 anatomical structure development; GO:0098754 detoxification; GO:0015918 sterol transport; GO:0016043 cellular component organization; GO:0007159 leukocyte cell-cell adhesion; GO:1902652 secondary alcohol metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0032368 regulation of lipid transport; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0045087 innate immune response; GO:0044058 regulation of digestive system process; GO:0071704 organic substance metabolic process; GO:0097006 regulation of plasma lipoprotein particle levels; GO:0034445 negative regulation of plasma lipoprotein particle oxidation; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:0044243 multicellular organismal catabolic process; GO:0006695 cholesterol biosynthetic process; GO:0072593 reactive oxygen species metabolic process; GO:1904729 regulation of intestinal lipid absorption; GO:0001523 retinoid metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0002227 innate immune response in mucosa; GO:0034371 chylomicron remodeling; GO:0071451 cellular response to superoxide; GO:0044712 single-organism catabolic process; GO:0051049 regulation of transport; GO:0006807 nitrogen compound metabolic process; GO:0042632 cholesterol homeostasis; GO:0031175 neuron projection development; GO:0048518 positive regulation of biological process; GO:0045834 positive regulation of lipid metabolic process; GO:0044249 cellular biosynthetic process; GO:0043085 positive regulation of catalytic activity; GO:0043933 macromolecular complex subunit organization; GO:0006820 anion transport; GO:0015711 organic anion transport; GO:1901701 cellular response to oxygen-containing compound; GO:0034645 cellular macromolecule biosynthetic process; GO:0055090 acylglycerol homeostasis; GO:0034380 high-density lipoprotein particle assembly; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0055092 sterol homeostasis; GO:0051248 negative regulation of protein metabolic process; GO:0006721 terpenoid metabolic process; GO:0031099 regeneration; GO:0034368 protein-lipid complex remodeling; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0005783 endoplasmic reticulum; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0034358 plasma lipoprotein particle; GO:0034385 triglyceride-rich plasma lipoprotein particle; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0034361 very-low-density lipoprotein particle; GO:0044422 organelle part; GO:0005769 early endosome; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0070013 intracellular organelle lumen; GO:0032994 protein-lipid complex; GO:0005622 intracellular; GO:0044464 cell part; GO:1990777 lipoprotein particle; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0005788 endoplasmic reticulum lumen; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0034364 high-density lipoprotein particle; GO:0042627 chylomicron; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0072562 blood microparticle; GO:0044432 endoplasmic reticulum part; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0015485 cholesterol binding; GO:0032934 sterol binding; GO:0070405 ammonium ion binding; GO:0046983 protein dimerization activity; GO:0043167 ion binding; GO:0016209 antioxidant activity; GO:0005319 lipid transporter activity; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0005507 copper ion binding; GO:0098772 molecular function regulator; GO:0005496 steroid binding; GO:0097159 organic cyclic compound binding; GO:0031210 phosphatidylcholine binding; GO:0050997 quaternary ammonium group binding; GO:0042802 identical protein binding; GO:0030234 enzyme regulator activity; GO:0046914 transition metal ion binding; GO:0017127 cholesterol transporter activity; GO:0042803 protein homodimerization activity; GO:0043178 alcohol binding; GO:0005488 binding; GO:0005543 phospholipid binding; GO:0015248 sterol transporter activity; GO:0008289 lipid binding; GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0043168 anion binding; GO:0008047 enzyme activator activity; GO:0036094 small molecule binding; GO:0005215 transporter activity; ","K08760","APOA4; apolipoprotein A-IV","hsa04975 Fat digestion and absorption - Homo sapiens (human); hsa04977 Vitamin digestion and absorption - Homo sapiens (human); hsa04979 Cholesterol metabolism - Homo sapiens (human); "]
["P06730","Eukaryotic translation initiation factor 4E OS=Homo sapiens OX=9606 GN=EIF4E","EIF4E",25.097,14.779,18.9,4,7,4,0.94,0.963,0.901,1.087,1.085,1.027,1.141,0.00808,"cytoplasm\r","GO:0050658 RNA transport; GO:0006518 peptide metabolic process; GO:0030323 respiratory tube development; GO:0010608 posttranscriptional regulation of gene expression; GO:0071384 cellular response to corticosteroid stimulus; GO:0051169 nuclear transport; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0007610 behavior; GO:0008152 metabolic process; GO:0015931 nucleobase-containing compound transport; GO:0071549 cellular response to dexamethasone stimulus; GO:0048545 response to steroid hormone; GO:0009719 response to endogenous stimulus; GO:0044770 cell cycle phase transition; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0008104 protein localization; GO:0044419 interspecies interaction between organisms; GO:0007399 nervous system development; GO:0000278 mitotic cell cycle; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0034249 negative regulation of cellular amide metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0031323 regulation of cellular metabolic process; GO:0006611 protein export from nucleus; GO:0032501 multicellular organismal process; GO:0071396 cellular response to lipid; GO:0051704 multi-organism process; GO:0050768 negative regulation of neurogenesis; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0048513 animal organ development; GO:0045931 positive regulation of mitotic cell cycle; GO:0032269 negative regulation of cellular protein metabolic process; GO:0006402 mRNA catabolic process; GO:0045665 negative regulation of neuron differentiation; GO:0044260 cellular macromolecule metabolic process; GO:0006913 nucleocytoplasmic transport; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0010721 negative regulation of cell development; GO:0016071 mRNA metabolic process; GO:0044708 single-organism behavior; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0044707 single-multicellular organism process; GO:0007346 regulation of mitotic cell cycle; GO:0051028 mRNA transport; GO:0044267 cellular protein metabolic process; GO:1901700 response to oxygen-containing compound; GO:0033555 multicellular organismal response to stress; GO:0017148 negative regulation of translation; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:1903047 mitotic cell cycle process; GO:0051239 regulation of multicellular organismal process; GO:0051236 establishment of RNA localization; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0060541 respiratory system development; GO:0009889 regulation of biosynthetic process; GO:0001662 behavioral fear response; GO:0044248 cellular catabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0007275 multicellular organism development; GO:0034613 cellular protein localization; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0045787 positive regulation of cell cycle; GO:0044772 mitotic cell cycle phase transition; GO:1901655 cellular response to ketone; GO:0006950 response to stress; GO:0071385 cellular response to glucocorticoid stimulus; GO:0048731 system development; GO:0006403 RNA localization; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0006405 RNA export from nucleus; GO:0071702 organic substance transport; GO:0071407 cellular response to organic cyclic compound; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0034248 regulation of cellular amide metabolic process; GO:0045184 establishment of protein localization; GO:0009890 negative regulation of biosynthetic process; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:1901564 organonitrogen compound metabolic process; GO:0051093 negative regulation of developmental process; GO:0048869 cellular developmental process; GO:0022008 neurogenesis; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0051168 nuclear export; GO:0044764 multi-organism cellular process; GO:0071383 cellular response to steroid hormone stimulus; GO:0051234 establishment of localization; GO:0071427 mRNA-containing ribonucleoprotein complex export from nucleus; GO:0051649 establishment of localization in cell; GO:0050657 nucleic acid transport; GO:0006413 translational initiation; GO:1901361 organic cyclic compound catabolic process; GO:0045596 negative regulation of cell differentiation; GO:0033036 macromolecule localization; GO:0006412 translation; GO:0051726 regulation of cell cycle; GO:0070887 cellular response to chemical stimulus; GO:0030324 lung development; GO:0032502 developmental process; GO:0035295 tube development; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0043043 peptide biosynthetic process; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0071166 ribonucleoprotein complex localization; GO:0051384 response to glucocorticoid; GO:0016070 RNA metabolic process; GO:0006401 RNA catabolic process; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0042221 response to chemical; GO:0090304 nucleic acid metabolic process; GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; GO:0045664 regulation of neuron differentiation; GO:0032870 cellular response to hormone stimulus; GO:0098727 maintenance of cell number; GO:0019222 regulation of metabolic process; GO:0006952 defense response; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0042596 fear response; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0033993 response to lipid; GO:0030154 cell differentiation; GO:0051961 negative regulation of nervous system development; GO:0016032 viral process; GO:0031960 response to corticosteroid; GO:0006886 intracellular protein transport; GO:0002209 behavioral defense response; GO:0034641 cellular nitrogen compound metabolic process; GO:0019827 stem cell population maintenance; GO:0009059 macromolecule biosynthetic process; GO:0000082 G1/S transition of mitotic cell cycle; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0006406 mRNA export from nucleus; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0044843 cell cycle G1/S phase transition; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0071548 response to dexamethasone; GO:0070727 cellular macromolecule localization; GO:1901701 cellular response to oxygen-containing compound; GO:0071426 ribonucleoprotein complex export from nucleus; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0071495 cellular response to endogenous stimulus; GO:0051246 regulation of protein metabolic process; GO:0006417 regulation of translation; GO:0044767 single-organism developmental process; GO:0009057 macromolecule catabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0010467 gene expression; GO:0031327 negative regulation of cellular biosynthetic process; GO:0043604 amide biosynthetic process; GO:0022402 cell cycle process; GO:0009725 response to hormone; GO:0009056 catabolic process; GO:0071705 nitrogen compound transport; GO:0007049 cell cycle; GO:0050767 regulation of neurogenesis; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; GO:1901654 response to ketone; ","GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0000932 P-body; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0034518 RNA cap binding complex; GO:0005623 cell; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0005845 mRNA cap binding complex; GO:0043227 membrane-bounded organelle; GO:0016281 eukaryotic translation initiation factor 4F complex; GO:0043229 intracellular organelle; GO:0010494 cytoplasmic stress granule; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0035770 ribonucleoprotein granule; GO:0031332 RNAi effector complex; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043234 protein complex; GO:0033391 chromatoid body; GO:0016442 RISC complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0003723 RNA binding; GO:0000339 RNA cap binding; GO:0000340 RNA 7-methylguanosine cap binding; GO:0003743 translation initiation factor activity; GO:0005515 protein binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0008135 translation factor activity, RNA binding; GO:0070491 repressing transcription factor binding; GO:0005488 binding; GO:0031369 translation initiation factor binding; GO:0003676 nucleic acid binding; GO:0031370 eukaryotic initiation factor 4G binding; GO:0008134 transcription factor binding; GO:0019899 enzyme binding; ","K03259","EIF4E; translation initiation factor 4E","hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa04066 HIF-1 signaling pathway - Homo sapiens (human); hsa01521 EGFR tyrosine kinase inhibitor resistance - Homo sapiens (human); hsa04910 Insulin signaling pathway - Homo sapiens (human); hsa03013 RNA transport - Homo sapiens (human); hsa04211 Longevity regulating pathway - Homo sapiens (human); hsa04150 mTOR signaling pathway - Homo sapiens (human); "]
["P06732","Creatine kinase M-type OS=Homo sapiens OX=9606 GN=CKM","CKM",43.101,27.273,13.4,4,5,4,0.342,0.318,1.351,1.437,1.278,1.215,1.954,0.195,"cytoplasm\r","GO:0016310 phosphorylation; GO:0044699 single-organism process; GO:0042398 cellular modified amino acid biosynthetic process; GO:0009058 biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0006575 cellular modified amino acid metabolic process; GO:0009987 cellular process; GO:0044281 small molecule metabolic process; GO:0046314 phosphocreatine biosynthetic process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:0006600 creatine metabolic process; GO:0044238 primary metabolic process; GO:1901605 alpha-amino acid metabolic process; GO:1901576 organic substance biosynthetic process; GO:0090407 organophosphate biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0019637 organophosphate metabolic process; GO:0042396 phosphagen biosynthetic process; GO:0006603 phosphocreatine metabolic process; GO:0006082 organic acid metabolic process; GO:0006599 phosphagen metabolic process; GO:0043436 oxoacid metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0044444 cytoplasmic part; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0004111 creatine kinase activity; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0016775 phosphotransferase activity, nitrogenous group as acceptor; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016301 kinase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0016740 transferase activity; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K00933","E2.7.3.2; creatine kinase [EC:2.7.3.2]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00330 Arginine and proline metabolism - Homo sapiens (human); ","IPR022413; IPR022414; IPR014746; ","\"ATP:guanido phosphotransferase, N-terminal; ATP:guanido phosphotransferase, catalytic domain; Glutamine synthetase/guanido kinase, catalytic domain; \"\r"]
["P06733","Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1","ENO1",47.168,323.31,49.8,21,107,20,0.961,0.935,0.953,1.043,1.066,1.043,1.106,0.000756,"cytoplasm\r","GO:0009116 nucleoside metabolic process; GO:0006165 nucleoside diphosphate phosphorylation; GO:0019362 pyridine nucleotide metabolic process; GO:0006096 glycolytic process; GO:0097659 nucleic acid-templated transcription; GO:0009185 ribonucleoside diphosphate metabolic process; GO:0044237 cellular metabolic process; GO:0009607 response to biotic stimulus; GO:0001558 regulation of cell growth; GO:0006006 glucose metabolic process; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0006094 gluconeogenesis; GO:0006091 generation of precursor metabolites and energy; GO:0032787 monocarboxylic acid metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0043170 macromolecule metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0044419 interspecies interaction between organisms; GO:0018130 heterocycle biosynthetic process; GO:0009179 purine ribonucleoside diphosphate metabolic process; GO:0080090 regulation of primary metabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0061620 glycolytic process through glucose-6-phosphate; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032774 RNA biosynthetic process; GO:0006732 coenzyme metabolic process; GO:0005975 carbohydrate metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0061718 glucose catabolic process to pyruvate; GO:0051704 multi-organism process; GO:1901575 organic substance catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0019674 NAD metabolic process; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0043436 oxoacid metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016310 phosphorylation; GO:0046496 nicotinamide nucleotide metabolic process; GO:0009259 ribonucleotide metabolic process; GO:0046364 monosaccharide biosynthetic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0006735 NADH regeneration; GO:0045892 negative regulation of transcription, DNA-templated; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:1901135 carbohydrate derivative metabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0009119 ribonucleoside metabolic process; GO:0044711 single-organism biosynthetic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0006163 purine nucleotide metabolic process; GO:0009890 negative regulation of biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0044283 small molecule biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0019320 hexose catabolic process; GO:0019318 hexose metabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0006757 ATP generation from ADP; GO:0046365 monosaccharide catabolic process; GO:0042278 purine nucleoside metabolic process; GO:0046031 ADP metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0019319 hexose biosynthetic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0046939 nucleotide phosphorylation; GO:0009135 purine nucleoside diphosphate metabolic process; GO:0072524 pyridine-containing compound metabolic process; GO:0051253 negative regulation of RNA metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0061615 glycolytic process through fructose-6-phosphate; GO:2001141 regulation of RNA biosynthetic process; GO:0006753 nucleoside phosphate metabolic process; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0010468 regulation of gene expression; GO:0045926 negative regulation of growth; GO:0031326 regulation of cellular biosynthetic process; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0055114 oxidation-reduction process; GO:1901360 organic cyclic compound metabolic process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051186 cofactor metabolic process; GO:0016052 carbohydrate catabolic process; GO:0016070 RNA metabolic process; GO:0030308 negative regulation of cell growth; GO:0044723 single-organism carbohydrate metabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:1902679 negative regulation of RNA biosynthetic process; GO:0019222 regulation of metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0006082 organic acid metabolic process; GO:0009615 response to virus; GO:0016051 carbohydrate biosynthetic process; GO:0040008 regulation of growth; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0006734 NADH metabolic process; GO:0043207 response to external biotic stimulus; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0071704 organic substance metabolic process; GO:0061621 canonical glycolysis; GO:0006090 pyruvate metabolic process; GO:0016032 viral process; GO:0005996 monosaccharide metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0009987 cellular process; GO:0009132 nucleoside diphosphate metabolic process; GO:0046034 ATP metabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0044724 single-organism carbohydrate catabolic process; GO:0010629 negative regulation of gene expression; GO:0044712 single-organism catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044282 small molecule catabolic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0046128 purine ribonucleoside metabolic process; GO:0006007 glucose catabolic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0019752 carboxylic acid metabolic process; GO:0010467 gene expression; GO:0009150 purine ribonucleotide metabolic process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0051128 regulation of cellular component organization; GO:0009056 catabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0030016 myofibril; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:1902494 catalytic complex; GO:0005622 intracellular; GO:0044464 cell part; GO:0043292 contractile fiber; GO:1903561 extracellular vesicle; GO:0044445 cytosolic part; GO:0031430 M band; GO:0043227 membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0099081 supramolecular polymer; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0031672 A band; GO:0030017 sarcomere; GO:0044449 contractile fiber part; GO:0000015 phosphopyruvate hydratase complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0000287 magnesium ion binding; GO:0003677 DNA binding; GO:0003723 RNA binding; GO:0004634 phosphopyruvate hydratase activity; GO:0043167 ion binding; GO:0016829 lyase activity; GO:0005515 protein binding; GO:0016836 hydro-lyase activity; GO:0016835 carbon-oxygen lyase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0050839 cell adhesion molecule binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0045296 cadherin binding; GO:0003676 nucleic acid binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0051020 GTPase binding; GO:0019899 enzyme binding; ","K01689","ENO; enolase [EC:4.2.1.11]","hsa03018 RNA degradation - Homo sapiens (human); hsa04066 HIF-1 signaling pathway - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human); hsa01230 Biosynthesis of amino acids - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); ","IPR029065; IPR029017; IPR020810; IPR020811; ","\"Enolase C-terminal domain-like; Enolase N-terminal domain-like; Enolase, C-terminal TIM barrel domain; Enolase, N-terminal; \"\r"]
["P06737","Glycogen phosphorylase, liver form OS=Homo sapiens OX=9606 GN=PYGL","PYGL",97.147,165.58,38.5,33,55,27,0.991,1.035,1.042,1,0.961,0.981,0.959,0.0982,"cytoplasm\r","GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0042593 glucose homeostasis; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0044264 cellular polysaccharide metabolic process; GO:0051234 establishment of localization; GO:0005980 glycogen catabolic process; GO:0046390 ribose phosphate biosynthetic process; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0006091 generation of precursor metabolites and energy; GO:0044262 cellular carbohydrate metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0043170 macromolecule metabolic process; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0002443 leukocyte mediated immunity; GO:0009251 glucan catabolic process; GO:0006073 cellular glucan metabolic process; GO:0055114 oxidation-reduction process; GO:0070265 necrotic cell death; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0005975 carbohydrate metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0016052 carbohydrate catabolic process; GO:0090407 organophosphate biosynthetic process; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0032940 secretion by cell; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0044260 cellular macromolecule metabolic process; GO:0043299 leukocyte degranulation; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0044275 cellular carbohydrate catabolic process; GO:0044042 glucan metabolic process; GO:0006112 energy reserve metabolic process; GO:0050896 response to stimulus; GO:0046391 5-phosphoribose 1-diphosphate metabolic process; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0005976 polysaccharide metabolic process; GO:0044248 cellular catabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0033500 carbohydrate homeostasis; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0044724 single-organism carbohydrate catabolic process; GO:0044712 single-organism catabolic process; GO:0044247 cellular polysaccharide catabolic process; GO:0016192 vesicle-mediated transport; GO:0005977 glycogen metabolic process; GO:0002376 immune system process; GO:0097300 programmed necrotic cell death; GO:0000272 polysaccharide catabolic process; GO:0044238 primary metabolic process; GO:0043312 neutrophil degranulation; GO:0002263 cell activation involved in immune response; GO:1901576 organic substance biosynthetic process; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0008219 cell death; GO:0006793 phosphorus metabolic process; GO:0009057 macromolecule catabolic process; GO:0019637 organophosphate metabolic process; GO:0001775 cell activation; GO:0012501 programmed cell death; GO:0070266 necroptotic process; GO:0006955 immune response; GO:0051179 localization; GO:0009056 catabolic process; GO:0065007 biological regulation; GO:0006887 exocytosis; ","GO:0034774 secretory granule lumen; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044433 cytoplasmic vesicle part; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0060205 cytoplasmic vesicle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:1901265 nucleoside phosphate binding; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:0048029 monosaccharide binding; GO:0005496 steroid binding; GO:0030170 pyridoxal phosphate binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0002054 nucleobase binding; GO:0042802 identical protein binding; GO:0016208 AMP binding; GO:0031406 carboxylic acid binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0008289 lipid binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0019842 vitamin binding; GO:0016758 transferase activity, transferring hexosyl groups; GO:0005536 glucose binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0043177 organic acid binding; GO:0000166 nucleotide binding; GO:0008144 drug binding; GO:0033293 monocarboxylic acid binding; GO:0048037 cofactor binding; GO:0032052 bile acid binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0002060 purine nucleobase binding; GO:0042803 protein homodimerization activity; GO:0004645 phosphorylase activity; GO:0030246 carbohydrate binding; GO:0016757 transferase activity, transferring glycosyl groups; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0008184 glycogen phosphorylase activity; GO:0036094 small molecule binding; ","K00688","PYG; glycogen phosphorylase [EC:2.4.1.1]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00500 Starch and sucrose metabolism - Homo sapiens (human); hsa04922 Glucagon signaling pathway - Homo sapiens (human); hsa04910 Insulin signaling pathway - Homo sapiens (human); hsa04217 Necroptosis - Homo sapiens (human); hsa04931 Insulin resistance - Homo sapiens (human); "]
["P06744","Glucose-6-phosphate isomerase OS=Homo sapiens OX=9606 GN=GPI","GPI",63.146,190.27,33,20,33,15,1.036,0.967,0.998,0.972,1.003,1.016,0.997,0.903,"cytoplasm\r","GO:0042181 ketone biosynthetic process; GO:0065008 regulation of biological quality; GO:0009116 nucleoside metabolic process; GO:0010941 regulation of cell death; GO:0045321 leukocyte activation; GO:0006165 nucleoside diphosphate phosphorylation; GO:0019362 pyridine nucleotide metabolic process; GO:0006096 glycolytic process; GO:0043009 chordate embryonic development; GO:0002262 myeloid cell homeostasis; GO:0042593 glucose homeostasis; GO:0043523 regulation of neuron apoptotic process; GO:0009185 ribonucleoside diphosphate metabolic process; GO:0044237 cellular metabolic process; GO:0050877 neurological system process; GO:0007610 behavior; GO:0006006 glucose metabolic process; GO:0009605 response to external stimulus; GO:0010466 negative regulation of peptidase activity; GO:0001525 angiogenesis; GO:0008152 metabolic process; GO:0006094 gluconeogenesis; GO:0006091 generation of precursor metabolites and energy; GO:0042180 cellular ketone metabolic process; GO:0014072 response to isoquinoline alkaloid; GO:0048545 response to steroid hormone; GO:0009719 response to endogenous stimulus; GO:0032787 monocarboxylic acid metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0009790 embryo development; GO:0048598 embryonic morphogenesis; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0052548 regulation of endopeptidase activity; GO:0014070 response to organic cyclic compound; GO:0002443 leukocyte mediated immunity; GO:0009179 purine ribonucleoside diphosphate metabolic process; GO:0060359 response to ammonium ion; GO:0080090 regulation of primary metabolic process; GO:0044281 small molecule metabolic process; GO:0001707 mesoderm formation; GO:0044763 single-organism cellular process; GO:0006081 cellular aldehyde metabolic process; GO:0061620 glycolytic process through glucose-6-phosphate; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0006732 coenzyme metabolic process; GO:0005975 carbohydrate metabolic process; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0061718 glucose catabolic process to pyruvate; GO:0006810 transport; GO:0007498 mesoderm development; GO:0048872 homeostasis of number of cells; GO:1901575 organic substance catabolic process; GO:0010243 response to organonitrogen compound; GO:0051336 regulation of hydrolase activity; GO:0001701 in utero embryonic development; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0019674 NAD metabolic process; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:1901698 response to nitrogen compound; GO:0009126 purine nucleoside monophosphate metabolic process; GO:0060548 negative regulation of cell death; GO:0044708 single-organism behavior; GO:0009438 methylglyoxal metabolic process; GO:0043436 oxoacid metabolic process; GO:0072359 circulatory system development; GO:0050794 regulation of cellular process; GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0044707 single-multicellular organism process; GO:0016310 phosphorylation; GO:0010951 negative regulation of endopeptidase activity; GO:0002283 neutrophil activation involved in immune response; GO:0046496 nicotinamide nucleotide metabolic process; GO:0009628 response to abiotic stimulus; GO:0009259 ribonucleotide metabolic process; GO:1901700 response to oxygen-containing compound; GO:0043067 regulation of programmed cell death; GO:0043279 response to alkaloid; GO:0046364 monosaccharide biosynthetic process; GO:0032355 response to estradiol; GO:0006735 NADH regeneration; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0035994 response to muscle stretch; GO:0009653 anatomical structure morphogenesis; GO:0051156 glucose 6-phosphate metabolic process; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0043524 negative regulation of neuron apoptotic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0035902 response to immobilization stress; GO:0044248 cellular catabolic process; GO:0033500 carbohydrate homeostasis; GO:1901135 carbohydrate derivative metabolic process; GO:0046184 aldehyde biosynthetic process; GO:0007275 multicellular organism development; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0009119 ribonucleoside metabolic process; GO:0048878 chemical homeostasis; GO:1901215 negative regulation of neuron death; GO:0045861 negative regulation of proteolysis; GO:0006950 response to stress; GO:0044711 single-organism biosynthetic process; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0072358 cardiovascular system development; GO:0002376 immune system process; GO:0009141 nucleoside triphosphate metabolic process; GO:0010033 response to organic substance; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0002263 cell activation involved in immune response; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0006163 purine nucleotide metabolic process; GO:0045055 regulated exocytosis; GO:0046185 aldehyde catabolic process; GO:0006793 phosphorus metabolic process; GO:0044283 small molecule biosynthetic process; GO:0001775 cell activation; GO:0019637 organophosphate metabolic process; GO:0019320 hexose catabolic process; GO:0051179 localization; GO:0006955 immune response; GO:0006887 exocytosis; GO:0019318 hexose metabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0046365 monosaccharide catabolic process; GO:0006757 ATP generation from ADP; GO:0042278 purine nucleoside metabolic process; GO:0046031 ADP metabolic process; GO:0019319 hexose biosynthetic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0001568 blood vessel development; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0046939 nucleotide phosphorylation; GO:0009135 purine nucleoside diphosphate metabolic process; GO:0072524 pyridine-containing compound metabolic process; GO:0061615 glycolytic process through fructose-6-phosphate; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0034101 erythrocyte homeostasis; GO:0048729 tissue morphogenesis; GO:0006753 nucleoside phosphate metabolic process; GO:0046686 response to cadmium ion; GO:0010035 response to inorganic substance; GO:0048514 blood vessel morphogenesis; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:0009888 tissue development; GO:0043278 response to morphine; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0001704 formation of primary germ layer; GO:2000116 regulation of cysteine-type endopeptidase activity; GO:0055114 oxidation-reduction process; GO:0002446 neutrophil mediated immunity; GO:0001944 vasculature development; GO:1901360 organic cyclic compound metabolic process; GO:0033574 response to testosterone; GO:0010605 negative regulation of macromolecule metabolic process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0010038 response to metal ion; GO:0051186 cofactor metabolic process; GO:0016052 carbohydrate catabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0042221 response to chemical; GO:0032940 secretion by cell; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0043299 leukocyte degranulation; GO:1901657 glycosyl compound metabolic process; GO:0052547 regulation of peptidase activity; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:0016051 carbohydrate biosynthetic process; GO:0043069 negative regulation of programmed cell death; GO:0006725 cellular aromatic compound metabolic process; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0032570 response to progesterone; GO:0006734 NADH metabolic process; GO:0006959 humoral immune response; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0007599 hemostasis; GO:0051346 negative regulation of hydrolase activity; GO:0071704 organic substance metabolic process; GO:0007369 gastrulation; GO:0061621 canonical glycolysis; GO:0009612 response to mechanical stimulus; GO:0033993 response to lipid; GO:0042592 homeostatic process; GO:0006090 pyruvate metabolic process; GO:0043066 negative regulation of apoptotic process; GO:0050890 cognition; GO:0005996 monosaccharide metabolic process; GO:2000117 negative regulation of cysteine-type endopeptidase activity; GO:0034641 cellular nitrogen compound metabolic process; GO:0036230 granulocyte activation; GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0009987 cellular process; GO:1901214 regulation of neuron death; GO:0009132 nucleoside diphosphate metabolic process; GO:0019242 methylglyoxal biosynthetic process; GO:0046034 ATP metabolic process; GO:0003008 system process; GO:0050878 regulation of body fluid levels; GO:0044724 single-organism carbohydrate catabolic process; GO:0044712 single-organism catabolic process; GO:0009792 embryo development ending in birth or egg hatching; GO:0006807 nitrogen compound metabolic process; GO:0044282 small molecule catabolic process; GO:0043312 neutrophil degranulation; GO:0007611 learning or memory; GO:0044249 cellular biosynthetic process; GO:0002366 leukocyte activation involved in immune response; GO:0046128 purine ribonucleoside metabolic process; GO:0042119 neutrophil activation; GO:0006007 glucose catabolic process; GO:0048332 mesoderm morphogenesis; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0009725 response to hormone; GO:0009056 catabolic process; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; GO:1901654 response to ketone; ","GO:0034774 secretory granule lumen; GO:0060170 ciliary membrane; GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0098590 plasma membrane region; GO:0044441 ciliary part; GO:0043209 myelin sheath; GO:0005622 intracellular; GO:0044425 membrane part; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043233 organelle lumen; GO:0005929 cilium; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0044459 plasma membrane part; GO:0031253 cell projection membrane; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0008083 growth factor activity; GO:0031625 ubiquitin protein ligase binding; GO:0005102 receptor binding; GO:0005515 protein binding; GO:0048029 monosaccharide binding; GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses; GO:0004347 glucose-6-phosphate isomerase activity; GO:0005125 cytokine activity; GO:0016853 isomerase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0030246 carbohydrate binding; GO:0016860 intramolecular oxidoreductase activity; GO:0044389 ubiquitin-like protein ligase binding; GO:0016866 intramolecular transferase activity; GO:0019899 enzyme binding; GO:0036094 small molecule binding; ","K01810","GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00500 Starch and sucrose metabolism - Homo sapiens (human); hsa00030 Pentose phosphate pathway - Homo sapiens (human); hsa00520 Amino sugar and nucleotide sugar metabolism - Homo sapiens (human); hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); ","IPR023096; ","\"Phosphoglucose isomerase, C-terminal; \"\r"]
["P06746","DNA polymerase beta OS=Homo sapiens OX=9606 GN=POLB","POLB",38.177,8.495,6,2,2,2,0.979,0.951,0.896,1.107,0.952,1.119,1.125,0.119,"cytoplasm\r","GO:0044700 single organism signaling; GO:0070646 protein modification by small protein removal; GO:0065008 regulation of biological quality; GO:0048732 gland development; GO:0006266 DNA ligation; GO:0070997 neuron death; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0098501 polynucleotide dephosphorylation; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0098502 DNA dephosphorylation; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0007154 cell communication; GO:0006915 apoptotic process; GO:0009314 response to radiation; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0006261 DNA-dependent DNA replication; GO:0006310 DNA recombination; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0051402 neuron apoptotic process; GO:0018130 heterocycle biosynthetic process; GO:0016446 somatic hypermutation of immunoglobulin genes; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0002520 immune system development; GO:0006288 base-excision repair, DNA ligation; GO:0048536 spleen development; GO:0070647 protein modification by small protein conjugation or removal; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0048872 homeostasis of number of cells; GO:0036296 response to increased oxygen levels; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0090304 nucleic acid metabolic process; GO:0002440 production of molecular mediator of immune response; GO:0048535 lymph node development; GO:0071707 immunoglobulin heavy chain V-D-J recombination; GO:0006287 base-excision repair, gap-filling; GO:0007568 aging; GO:0006954 inflammatory response; GO:0044260 cellular macromolecule metabolic process; GO:0009887 animal organ morphogenesis; GO:0006464 cellular protein modification process; GO:0006952 defense response; GO:0036211 protein modification process; GO:0006286 base-excision repair, base-free sugar-phosphate removal; GO:0048856 anatomical structure development; GO:1901362 organic cyclic compound biosynthetic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0044707 single-multicellular organism process; GO:0097190 apoptotic signaling pathway; GO:0006260 DNA replication; GO:0006725 cellular aromatic compound metabolic process; GO:0006259 DNA metabolic process; GO:0002200 somatic diversification of immune receptors; GO:0016445 somatic diversification of immunoglobulins; GO:0009628 response to abiotic stimulus; GO:0045471 response to ethanol; GO:0010332 response to gamma radiation; GO:1901700 response to oxygen-containing compound; GO:0044267 cellular protein metabolic process; GO:0007431 salivary gland development; GO:0050896 response to stimulus; GO:0016579 protein deubiquitination; GO:0002562 somatic diversification of immune receptors via germline recombination within a single locus; GO:0097193 intrinsic apoptotic signaling pathway; GO:0071704 organic substance metabolic process; GO:0009653 anatomical structure morphogenesis; GO:0042592 homeostatic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0033152 immunoglobulin V(D)J recombination; GO:0070482 response to oxygen levels; GO:0034641 cellular nitrogen compound metabolic process; GO:0006508 proteolysis; GO:0071897 DNA biosynthetic process; GO:0007275 multicellular organism development; GO:0055093 response to hyperoxia; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0035272 exocrine system development; GO:0006284 base-excision repair; GO:0016444 somatic cell DNA recombination; GO:0006950 response to stress; GO:0016447 somatic recombination of immunoglobulin gene segments; GO:0035556 intracellular signal transduction; GO:0048731 system development; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0033151 V(D)J recombination; GO:0002376 immune system process; GO:0097305 response to alcohol; GO:0051103 DNA ligation involved in DNA repair; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0016311 dephosphorylation; GO:1901576 organic substance biosynthetic process; GO:0048534 hematopoietic or lymphoid organ development; GO:0006974 cellular response to DNA damage stimulus; GO:0044249 cellular biosynthetic process; GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage; GO:0006281 DNA repair; GO:0010212 response to ionizing radiation; GO:0002377 immunoglobulin production; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0007435 salivary gland morphogenesis; GO:0012501 programmed cell death; GO:0043412 macromolecule modification; GO:0002566 somatic diversification of immune receptors via somatic mutation; GO:0006290 pyrimidine dimer repair; GO:0022612 gland morphogenesis; GO:0065007 biological regulation; ","GO:0005874 microtubule; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0005623 cell; GO:0099080 supramolecular complex; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005819 spindle; GO:0099081 supramolecular polymer; GO:0005876 spindle microtubule; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0043234 protein complex; GO:0044428 nuclear part; ","GO:0003677 DNA binding; GO:0004536 deoxyribonuclease activity; GO:0043167 ion binding; GO:0015631 tubulin binding; GO:0004520 endodeoxyribonuclease activity; GO:0016829 lyase activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0016835 carbon-oxygen lyase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity; GO:0008092 cytoskeletal protein binding; GO:0016779 nucleotidyltransferase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0008017 microtubule binding; GO:0003676 nucleic acid binding; GO:0004518 nuclease activity; GO:0016788 hydrolase activity, acting on ester bonds; GO:0034061 DNA polymerase activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0003887 DNA-directed DNA polymerase activity; GO:0003684 damaged DNA binding; GO:0016740 transferase activity; GO:0019899 enzyme binding; GO:0004519 endonuclease activity; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K02330","POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]","hsa05166 HTLV-I infection - Homo sapiens (human); hsa03410 Base excision repair - Homo sapiens (human); hsa05203 Viral carcinogenesis - Homo sapiens (human); ","IPR029398; IPR018944; IPR003583; IPR027420; IPR010996; IPR002054; IPR028207; ","\"DNA polymerase beta, thumb domain; DNA polymerase lambda, fingers domain; Helix-hairpin-helix DNA-binding motif, class 1; DNA polymerase beta, N-terminal domain; DNA polymerase beta-like, N-terminal domain; DNA-directed DNA polymerase X; DNA polymerase beta, palm domain; \"\r"]
["P06748","Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1","NPM1",32.575,120.25,41.8,11,39,11,0.862,0.852,0.866,1.181,1.155,1.125,1.341,3.93E-5,"nucleus\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:1902807 negative regulation of cell cycle G1/S phase transition; GO:0010941 regulation of cell death; GO:0010608 posttranscriptional regulation of gene expression; GO:0009891 positive regulation of biosynthetic process; GO:0044237 cellular metabolic process; GO:0010564 regulation of cell cycle process; GO:0072431 signal transduction involved in mitotic G1 DNA damage checkpoint; GO:1902403 signal transduction involved in mitotic DNA integrity checkpoint; GO:0008152 metabolic process; GO:0034724 DNA replication-independent nucleosome organization; GO:0065003 macromolecular complex assembly; GO:0044093 positive regulation of molecular function; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0051493 regulation of cytoskeleton organization; GO:0090068 positive regulation of cell cycle process; GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation; GO:0060735 regulation of eIF2 alpha phosphorylation by dsRNA; GO:0000278 mitotic cell cycle; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0044773 mitotic DNA damage checkpoint; GO:0080090 regulation of primary metabolic process; GO:2000134 negative regulation of G1/S transition of mitotic cell cycle; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:1902751 positive regulation of cell cycle G2/M phase transition; GO:0043086 negative regulation of catalytic activity; GO:0051704 multi-organism process; GO:0006810 transport; GO:0032886 regulation of microtubule-based process; GO:0000226 microtubule cytoskeleton organization; GO:0051092 positive regulation of NF-kappaB transcription factor activity; GO:0080135 regulation of cellular response to stress; GO:1902400 intracellular signal transduction involved in G1 DNA damage checkpoint; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:1901698 response to nitrogen compound; GO:0006913 nucleocytoplasmic transport; GO:0060548 negative regulation of cell death; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0034728 nucleosome organization; GO:0043486 histone exchange; GO:0006259 DNA metabolic process; GO:0051297 centrosome organization; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:1901989 positive regulation of cell cycle phase transition; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1902402 signal transduction involved in mitotic DNA damage checkpoint; GO:0009889 regulation of biosynthetic process; GO:0044819 mitotic G1/S transition checkpoint; GO:1902680 positive regulation of RNA biosynthetic process; GO:0034613 cellular protein localization; GO:0006336 DNA replication-independent nucleosome assembly; GO:0071359 cellular response to dsRNA; GO:0010826 negative regulation of centrosome duplication; GO:0006950 response to stress; GO:0072331 signal transduction by p53 class mediator; GO:0010033 response to organic substance; GO:0006974 cellular response to DNA damage stimulus; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0034248 regulation of cellular amide metabolic process; GO:0031055 chromatin remodeling at centromere; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0045936 negative regulation of phosphate metabolic process; GO:0008284 positive regulation of cell proliferation; GO:2000045 regulation of G1/S transition of mitotic cell cycle; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0031400 negative regulation of protein modification process; GO:0046599 regulation of centriole replication; GO:2001141 regulation of RNA biosynthetic process; GO:0045930 negative regulation of mitotic cell cycle; GO:0007165 signal transduction; GO:0000077 DNA damage checkpoint; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:1902806 regulation of cell cycle G1/S phase transition; GO:0033036 macromolecule localization; GO:0051726 regulation of cell cycle; GO:0071824 protein-DNA complex subunit organization; GO:0031571 mitotic G1 DNA damage checkpoint; GO:0031326 regulation of cellular biosynthetic process; GO:0051494 negative regulation of cytoskeleton organization; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0032071 regulation of endodeoxyribonuclease activity; GO:0051052 regulation of DNA metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0006325 chromatin organization; GO:0070271 protein complex biogenesis; GO:0072401 signal transduction involved in DNA integrity checkpoint; GO:0043549 regulation of kinase activity; GO:0016043 cellular component organization; GO:0072395 signal transduction involved in cell cycle checkpoint; GO:0045786 negative regulation of cell cycle; GO:0043069 negative regulation of programmed cell death; GO:1901988 negative regulation of cell cycle phase transition; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0071704 organic substance metabolic process; GO:0070925 organelle assembly; GO:0043066 negative regulation of apoptotic process; GO:0016032 viral process; GO:0006886 intracellular protein transport; GO:0034641 cellular nitrogen compound metabolic process; GO:0034622 cellular macromolecular complex assembly; GO:0006355 regulation of transcription, DNA-templated; GO:0072422 signal transduction involved in DNA damage checkpoint; GO:0035556 intracellular signal transduction; GO:0001932 regulation of protein phosphorylation; GO:0033043 regulation of organelle organization; GO:1902749 regulation of cell cycle G2/M phase transition; GO:0043933 macromolecular complex subunit organization; GO:0006281 DNA repair; GO:0031023 microtubule organizing center organization; GO:0010563 negative regulation of phosphorus metabolic process; GO:0071158 positive regulation of cell cycle arrest; GO:0051248 negative regulation of protein metabolic process; GO:0022402 cell cycle process; GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; GO:0042981 regulation of apoptotic process; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0032270 positive regulation of cellular protein metabolic process; GO:0022618 ribonucleoprotein complex assembly; GO:0051169 nuclear transport; GO:0015031 protein transport; GO:0008285 negative regulation of cell proliferation; GO:0006334 nucleosome assembly; GO:0010824 regulation of centrosome duplication; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0008104 protein localization; GO:0014070 response to organic cyclic compound; GO:0051174 regulation of phosphorus metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0034508 centromere complex assembly; GO:0042254 ribosome biogenesis; GO:0031323 regulation of cellular metabolic process; GO:0043044 ATP-dependent chromatin remodeling; GO:0065004 protein-DNA complex assembly; GO:1903506 regulation of nucleic acid-templated transcription; GO:0010948 negative regulation of cell cycle process; GO:0007569 cell aging; GO:0072413 signal transduction involved in mitotic cell cycle checkpoint; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0051090 regulation of sequence-specific DNA binding transcription factor activity; GO:0060699 regulation of endoribonuclease activity; GO:0010604 positive regulation of macromolecule metabolic process; GO:0034080 CENP-A containing nucleosome assembly; GO:0046605 regulation of centrosome cycle; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0033554 cellular response to stress; GO:0006338 chromatin remodeling; GO:0007346 regulation of mitotic cell cycle; GO:0042127 regulation of cell proliferation; GO:0031399 regulation of protein modification process; GO:0043067 regulation of programmed cell death; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:0051259 protein oligomerization; GO:0030330 DNA damage response, signal transduction by p53 class mediator; GO:0006323 DNA packaging; GO:0032069 regulation of nuclease activity; GO:0010628 positive regulation of gene expression; GO:1901987 regulation of cell cycle phase transition; GO:0051338 regulation of transferase activity; GO:0007093 mitotic cell cycle checkpoint; GO:0051171 regulation of nitrogen compound metabolic process; GO:0001933 negative regulation of protein phosphorylation; GO:0007010 cytoskeleton organization; GO:0006461 protein complex assembly; GO:0045787 positive regulation of cell cycle; GO:0051254 positive regulation of RNA metabolic process; GO:0071702 organic substance transport; GO:0071407 cellular response to organic cyclic compound; GO:0044238 primary metabolic process; GO:0007017 microtubule-based process; GO:0009892 negative regulation of metabolic process; GO:0042255 ribosome assembly; GO:0045184 establishment of protein localization; GO:0051247 positive regulation of protein metabolic process; GO:0051276 chromosome organization; GO:0051179 localization; GO:0031328 positive regulation of cellular biosynthetic process; GO:0007098 centrosome cycle; GO:0051129 negative regulation of cellular component organization; GO:0044783 G1 DNA damage checkpoint; GO:0044764 multi-organism cellular process; GO:1902115 regulation of organelle assembly; GO:0051234 establishment of localization; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0071826 ribonucleoprotein complex subunit organization; GO:0044774 mitotic DNA integrity checkpoint; GO:0022607 cellular component assembly; GO:1901991 negative regulation of mitotic cell cycle phase transition; GO:0033673 negative regulation of kinase activity; GO:0000075 cell cycle checkpoint; GO:0031497 chromatin assembly; GO:0070887 cellular response to chemical stimulus; GO:0071103 DNA conformation change; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0006333 chromatin assembly or disassembly; GO:0071822 protein complex subunit organization; GO:0045727 positive regulation of translation; GO:0060700 regulation of ribonuclease activity; GO:0031570 DNA integrity checkpoint; GO:0043331 response to dsRNA; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity; GO:0051348 negative regulation of transferase activity; GO:0010639 negative regulation of organelle organization; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:1901699 cellular response to nitrogen compound; GO:0007568 aging; GO:0019222 regulation of metabolic process; GO:0006469 negative regulation of protein kinase activity; GO:0046606 negative regulation of centrosome cycle; GO:0019220 regulation of phosphate metabolic process; GO:0045859 regulation of protein kinase activity; GO:0006725 cellular aromatic compound metabolic process; GO:0032070 regulation of deoxyribonuclease activity; GO:0061641 CENP-A containing chromatin organization; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044087 regulation of cellular component biogenesis; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0042326 negative regulation of phosphorylation; GO:0042770 signal transduction in response to DNA damage; GO:0009987 cellular process; GO:0070507 regulation of microtubule cytoskeleton organization; GO:0071156 regulation of cell cycle arrest; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0051641 cellular localization; GO:0070727 cellular macromolecule localization; GO:0006417 regulation of translation; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0006446 regulation of translational initiation; GO:0034250 positive regulation of cellular amide metabolic process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0051128 regulation of cellular component organization; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0005815 microtubule organizing center; GO:0005654 nucleoplasm; GO:0005925 focal adhesion; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0031616 spindle pole centrosome; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0000922 spindle pole; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0005819 spindle; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0005813 centrosome; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0046983 protein dimerization activity; GO:0019901 protein kinase binding; GO:0005515 protein binding; GO:0004860 protein kinase inhibitor activity; GO:0019207 kinase regulator activity; GO:0043023 ribosomal large subunit binding; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0042802 identical protein binding; GO:0043024 ribosomal small subunit binding; GO:0005488 binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0030957 Tat protein binding; GO:0042393 histone binding; GO:0003723 RNA binding; GO:0046982 protein heterodimerization activity; GO:0044877 macromolecular complex binding; GO:0019887 protein kinase regulator activity; GO:0019900 kinase binding; GO:0003712 transcription cofactor activity; GO:0030234 enzyme regulator activity; GO:0019210 kinase inhibitor activity; GO:0042803 protein homodimerization activity; GO:0003676 nucleic acid binding; GO:0051059 NF-kappaB binding; GO:0003713 transcription coactivator activity; GO:0051082 unfolded protein binding; GO:0000988 transcription factor activity, protein binding; GO:0043021 ribonucleoprotein complex binding; GO:0019899 enzyme binding; GO:0008134 transcription factor binding; ","K11276",null,null,"IPR024057; IPR032569; ","\"Nucleoplasmin core domain; Nucleophosmin, C-terminal; \"\r"]
["P06753","Tropomyosin alpha-3 chain OS=Homo sapiens OX=9606 GN=TPM3","TPM3",32.95,22.004,46.3,19,42,5,1.022,0.995,1.002,1.014,0.992,0.974,0.987,0.407,"cytoplasm\r","GO:0030048 actin filament-based movement; GO:0016043 cellular component organization; GO:0030049 muscle filament sliding; GO:0070252 actin-mediated cell contraction; GO:0003012 muscle system process; GO:0003008 system process; GO:0033275 actin-myosin filament sliding; GO:0044763 single-organism cellular process; GO:0007015 actin filament organization; GO:0044699 single-organism process; GO:0032501 multicellular organismal process; GO:1902589 single-organism organelle organization; GO:0030036 actin cytoskeleton organization; GO:0006936 muscle contraction; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0006928 movement of cell or subcellular component; GO:0007010 cytoskeleton organization; GO:0097435 supramolecular fiber organization; GO:0009987 cellular process; GO:0071840 cellular component organization or biogenesis; ","GO:0044421 extracellular region part; GO:0030016 myofibril; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0032432 actin filament bundle; GO:0044422 organelle part; GO:0005862 muscle thin filament tropomyosin; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005856 cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043292 contractile fiber; GO:0005884 actin filament; GO:0005865 striated muscle thin filament; GO:0001725 stress fiber; GO:0043227 membrane-bounded organelle; GO:0042641 actomyosin; GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0097517 contractile actin filament bundle; GO:0005829 cytosol; GO:0015629 actin cytoskeleton; GO:0005576 extracellular region; GO:0036379 myofilament; GO:0099081 supramolecular polymer; GO:0043226 organelle; GO:0030017 sarcomere; GO:0044449 contractile fiber part; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0051015 actin filament binding; GO:0008092 cytoskeletal protein binding; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0003779 actin binding; GO:0005515 protein binding; GO:0008307 structural constituent of muscle; GO:0005198 structural molecule activity; GO:0032403 protein complex binding; ","K09290","TPM3; tropomyosin 3","hsa04260 Cardiac muscle contraction - Homo sapiens (human); hsa05216 Thyroid cancer - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa05414 Dilated cardiomyopathy (DCM) - Homo sapiens (human); hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human); hsa05410 Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human); "]
["P06756","Integrin alpha-V OS=Homo sapiens OX=9606 GN=ITGAV","ITGAV",116.04,67.325,9,9,14,9,1.066,1.024,1.103,0.901,0.925,0.938,0.866,0.0042,"plasma membrane\r","GO:0044700 single organism signaling; GO:0044409 entry into host; GO:0010941 regulation of cell death; GO:0052370 entry of organism into cell of other organism by promotion of phagocytosis in other organism involved in symbiotic interaction; GO:0044237 cellular metabolic process; GO:0007492 endoderm development; GO:0008152 metabolic process; GO:0001525 angiogenesis; GO:0055065 metal ion homeostasis; GO:0007160 cell-matrix adhesion; GO:0009790 embryo development; GO:0048598 embryonic morphogenesis; GO:0033690 positive regulation of osteoblast proliferation; GO:0046718 viral entry into host cell; GO:0051051 negative regulation of transport; GO:0042325 regulation of phosphorylation; GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0048870 cell motility; GO:0006935 chemotaxis; GO:0006874 cellular calcium ion homeostasis; GO:0051704 multi-organism process; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0006810 transport; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0000165 MAPK cascade; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0098602 single organism cell adhesion; GO:0010871 negative regulation of receptor biosynthetic process; GO:0048010 vascular endothelial growth factor receptor signaling pathway; GO:0060548 negative regulation of cell death; GO:0098662 inorganic cation transmembrane transport; GO:0072359 circulatory system development; GO:0016310 phosphorylation; GO:0044707 single-multicellular organism process; GO:0034220 ion transmembrane transport; GO:0097190 apoptotic signaling pathway; GO:0030001 metal ion transport; GO:0051806 entry into cell of other organism involved in symbiotic interaction; GO:0045714 regulation of low-density lipoprotein particle receptor biosynthetic process; GO:0048519 negative regulation of biological process; GO:0001570 vasculogenesis; GO:0051817 modification of morphology or physiology of other organism involved in symbiotic interaction; GO:0009653 anatomical structure morphogenesis; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0009889 regulation of biosynthetic process; GO:2000145 regulation of cell motility; GO:0043062 extracellular structure organization; GO:0038027 apolipoprotein A-I-mediated signaling pathway; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0050746 regulation of lipoprotein metabolic process; GO:0048878 chemical homeostasis; GO:0070588 calcium ion transmembrane transport; GO:0023014 signal transduction by protein phosphorylation; GO:0052231 modulation of phagocytosis in other organism involved in symbiotic interaction; GO:0030100 regulation of endocytosis; GO:0045785 positive regulation of cell adhesion; GO:0050919 negative chemotaxis; GO:0051270 regulation of cellular component movement; GO:0050766 positive regulation of phagocytosis; GO:0002376 immune system process; GO:0002263 cell activation involved in immune response; GO:0045055 regulated exocytosis; GO:0009890 negative regulation of biosynthetic process; GO:0010883 regulation of lipid storage; GO:0031325 positive regulation of cellular metabolic process; GO:0006955 immune response; GO:0043412 macromolecule modification; GO:0040007 growth; GO:0070838 divalent metal ion transport; GO:0008284 positive regulation of cell proliferation; GO:0051093 negative regulation of developmental process; GO:0009968 negative regulation of signal transduction; GO:0051674 localization of cell; GO:0001568 blood vessel development; GO:0040017 positive regulation of locomotion; GO:0033627 cell adhesion mediated by integrin; GO:0023051 regulation of signaling; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0006796 phosphate-containing compound metabolic process; GO:0044068 modulation by symbiont of host cellular process; GO:0016337 single organismal cell-cell adhesion; GO:0007165 signal transduction; GO:0009893 positive regulation of metabolic process; GO:0006915 apoptotic process; GO:0030198 extracellular matrix organization; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0045937 positive regulation of phosphate metabolic process; GO:0098609 cell-cell adhesion; GO:0098771 inorganic ion homeostasis; GO:0001944 vasculature development; GO:0023052 signaling; GO:0007229 integrin-mediated signaling pathway; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0032940 secretion by cell; GO:2001236 regulation of extrinsic apoptotic signaling pathway; GO:0010745 negative regulation of macrophage derived foam cell differentiation; GO:0036211 protein modification process; GO:0016043 cellular component organization; GO:0016477 cell migration; GO:0043069 negative regulation of programmed cell death; GO:0072511 divalent inorganic cation transport; GO:0010869 regulation of receptor biosynthetic process; GO:0060255 regulation of macromolecule metabolic process; GO:0070371 ERK1 and ERK2 cascade; GO:0019058 viral life cycle; GO:0032368 regulation of lipid transport; GO:0071704 organic substance metabolic process; GO:0000904 cell morphogenesis involved in differentiation; GO:0007369 gastrulation; GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:0006468 protein phosphorylation; GO:0043408 regulation of MAPK cascade; GO:0043066 negative regulation of apoptotic process; GO:0055080 cation homeostasis; GO:0023056 positive regulation of signaling; GO:0043277 apoptotic cell clearance; GO:0016032 viral process; GO:0010647 positive regulation of cell communication; GO:0010888 negative regulation of lipid storage; GO:0045595 regulation of cell differentiation; GO:0052190 modulation by symbiont of host phagocytosis; GO:0001706 endoderm formation; GO:0035987 endodermal cell differentiation; GO:0035556 intracellular signal transduction; GO:0051049 regulation of transport; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:0001932 regulation of protein phosphorylation; GO:0001934 positive regulation of protein phosphorylation; GO:0043901 negative regulation of multi-organism process; GO:0002366 leukocyte activation involved in immune response; GO:0019882 antigen processing and presentation; GO:0042119 neutrophil activation; GO:0008219 cell death; GO:0051248 negative regulation of protein metabolic process; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0060627 regulation of vesicle-mediated transport; GO:0030335 positive regulation of cell migration; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0045321 leukocyte activation; GO:0007166 cell surface receptor signaling pathway; GO:0032989 cellular component morphogenesis; GO:0022610 biological adhesion; GO:0009605 response to external stimulus; GO:0034446 substrate adhesion-dependent cell spreading; GO:0032879 regulation of localization; GO:0044003 modification by symbiont of host morphology or physiology; GO:0007155 cell adhesion; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0044419 interspecies interaction between organisms; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0051174 regulation of phosphorus metabolic process; GO:0002443 leukocyte mediated immunity; GO:0016049 cell growth; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0051272 positive regulation of cellular component movement; GO:0052066 entry of symbiont into host cell by promotion of host phagocytosis; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0000902 cell morphogenesis; GO:0050900 leukocyte migration; GO:0044710 single-organism metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0042330 taxis; GO:0050794 regulation of cellular process; GO:2000535 regulation of entry of bacterium into host cell; GO:0097191 extrinsic apoptotic signaling pathway; GO:0002283 neutrophil activation involved in immune response; GO:0042127 regulation of cell proliferation; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0043067 regulation of programmed cell death; GO:2000147 positive regulation of cell motility; GO:0048523 negative regulation of cellular process; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0007275 multicellular organism development; GO:0050748 negative regulation of lipoprotein metabolic process; GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; GO:0009966 regulation of signal transduction; GO:1902531 regulation of intracellular signal transduction; GO:0048731 system development; GO:0043900 regulation of multi-organism process; GO:0016192 vesicle-mediated transport; GO:0030334 regulation of cell migration; GO:0072358 cardiovascular system development; GO:2001237 negative regulation of extrinsic apoptotic signaling pathway; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0030155 regulation of cell adhesion; GO:0055085 transmembrane transport; GO:0051247 positive regulation of protein metabolic process; GO:0006873 cellular ion homeostasis; GO:0006793 phosphorus metabolic process; GO:0006811 ion transport; GO:0001775 cell activation; GO:0006928 movement of cell or subcellular component; GO:0012501 programmed cell death; GO:0048584 positive regulation of response to stimulus; GO:0007204 positive regulation of cytosolic calcium ion concentration; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0006887 exocytosis; GO:2000425 regulation of apoptotic cell clearance; GO:0072503 cellular divalent inorganic cation homeostasis; GO:0052191 positive regulation by symbiont of host phagocytosis; GO:1902533 positive regulation of intracellular signal transduction; GO:0044764 multi-organism cellular process; GO:0035821 modification of morphology or physiology of other organism; GO:0034113 heterotypic cell-cell adhesion; GO:0033688 regulation of osteoblast proliferation; GO:0051234 establishment of localization; GO:0006909 phagocytosis; GO:0051130 positive regulation of cellular component organization; GO:2001233 regulation of apoptotic signaling pathway; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I; GO:0048514 blood vessel morphogenesis; GO:0045596 negative regulation of cell differentiation; GO:0050764 regulation of phagocytosis; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:0098655 cation transmembrane transport; GO:0009888 tissue development; GO:0050801 ion homeostasis; GO:0032369 negative regulation of lipid transport; GO:0001704 formation of primary germ layer; GO:0055074 calcium ion homeostasis; GO:0010743 regulation of macrophage derived foam cell differentiation; GO:0002446 neutrophil mediated immunity; GO:0048002 antigen processing and presentation of peptide antigen; GO:0019725 cellular homeostasis; GO:0048522 positive regulation of cellular process; GO:0051050 positive regulation of transport; GO:0030260 entry into host cell; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0051828 entry into other organism involved in symbiotic interaction; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0043299 leukocyte degranulation; GO:0052522 positive regulation by organism of phagocytosis in other organism involved in symbiotic interaction; GO:0040011 locomotion; GO:0072507 divalent inorganic cation homeostasis; GO:0048856 anatomical structure development; GO:0038034 signal transduction in absence of ligand; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:2000536 negative regulation of entry of bacterium into host cell; GO:0002252 immune effector process; GO:0045807 positive regulation of endocytosis; GO:0051480 regulation of cytosolic calcium ion concentration; GO:0030003 cellular cation homeostasis; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0055082 cellular chemical homeostasis; GO:0048468 cell development; GO:0006812 cation transport; GO:0006816 calcium ion transport; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0098660 inorganic ion transmembrane transport; GO:0031401 positive regulation of protein modification process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0043312 neutrophil degranulation; GO:0051701 interaction with host; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0031589 cell-substrate adhesion; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0006875 cellular metal ion homeostasis; GO:0009967 positive regulation of signal transduction; GO:0051128 regulation of cellular component organization; GO:0043410 positive regulation of MAPK cascade; GO:0040012 regulation of locomotion; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0009897 external side of plasma membrane; GO:0031090 organelle membrane; GO:0032587 ruffle membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0034683 integrin alphav-beta3 complex; GO:0005887 integral component of plasma membrane; GO:0098858 actin-based cell projection; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0098590 plasma membrane region; GO:0031256 leading edge membrane; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0030027 lamellipodium; GO:0030175 filopodium; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0098552 side of membrane; GO:0031252 cell leading edge; GO:0042995 cell projection; GO:0031226 intrinsic component of plasma membrane; GO:0098802 plasma membrane receptor complex; GO:0098797 plasma membrane protein complex; GO:0070161 anchoring junction; GO:0043235 receptor complex; GO:0012506 vesicle membrane; GO:0005576 extracellular region; GO:0031527 filopodium membrane; GO:0005886 plasma membrane; GO:0030667 secretory granule membrane; GO:0005902 microvillus; GO:0034684 integrin alphav-beta5 complex; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0098636 protein complex involved in cell adhesion; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0030054 cell junction; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex; GO:0044424 intracellular part; GO:0044425 membrane part; GO:0044464 cell part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0005912 adherens junction; GO:0030141 secretory granule; GO:0030139 endocytic vesicle; GO:0035579 specific granule membrane; GO:0031528 microvillus membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0045335 phagocytic vesicle; GO:0008305 integrin complex; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0016021 integral component of membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0042581 specific granule; GO:0031258 lamellipodium membrane; GO:0001726 ruffle; GO:0031253 cell projection membrane; GO:0009986 cell surface; GO:0034686 integrin alphav-beta8 complex; GO:0044444 cytoplasmic part; ","GO:0005102 receptor binding; GO:0019838 growth factor binding; GO:0001846 opsonin binding; GO:0015026 coreceptor activity; GO:0019901 protein kinase binding; GO:0022803 passive transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0004871 signal transducer activity; GO:0050840 extracellular matrix binding; GO:0015267 channel activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0046873 metal ion transmembrane transporter activity; GO:0042277 peptide binding; GO:0005488 binding; GO:0043169 cation binding; GO:0005216 ion channel activity; GO:0022890 inorganic cation transmembrane transporter activity; GO:0005215 transporter activity; GO:0038023 signaling receptor activity; GO:0001968 fibronectin binding; GO:0005245 voltage-gated calcium channel activity; GO:0015075 ion transmembrane transporter activity; GO:0043167 ion binding; GO:1990430 extracellular matrix protein binding; GO:0033218 amide binding; GO:0019900 kinase binding; GO:0001618 virus receptor activity; GO:0050431 transforming growth factor beta binding; GO:0002020 protease binding; GO:0005244 voltage-gated ion channel activity; GO:0019955 cytokine binding; GO:0060089 molecular transducer activity; GO:0072509 divalent inorganic cation transmembrane transporter activity; GO:0004872 receptor activity; GO:0022838 substrate-specific channel activity; GO:0022843 voltage-gated cation channel activity; GO:0005261 cation channel activity; GO:0046872 metal ion binding; GO:0015085 calcium ion transmembrane transporter activity; GO:0005080 protein kinase C binding; GO:0022836 gated channel activity; GO:0022832 voltage-gated channel activity; GO:0005262 calcium channel activity; GO:0008324 cation transmembrane transporter activity; GO:0019899 enzyme binding; GO:0022857 transmembrane transporter activity; ","K06487","ITGAV; integrin alpha V","hsa05200 Pathways in cancer - Homo sapiens (human); hsa05414 Dilated cardiomyopathy (DCM) - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa05222 Small cell lung cancer - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human); hsa04512 ECM-receptor interaction - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); hsa05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human); hsa04514 Cell adhesion molecules (CAMs) - Homo sapiens (human); hsa05410 Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human); ","IPR032695; IPR013649; ","Integrin domain; Integrin alpha-2; \r"]
["P06865","Beta-hexosaminidase subunit alpha OS=Homo sapiens OX=9606 GN=HEXA","HEXA",60.702,30.478,15.7,9,14,9,1.024,1.017,1.008,0.993,0.958,0.979,0.961,0.0248,"mitochondria\r","GO:1903509 liposaccharide metabolic process; GO:0006643 membrane lipid metabolic process; GO:0006024 glycosaminoglycan biosynthetic process; GO:0006687 glycosphingolipid metabolic process; GO:0006026 aminoglycan catabolic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0009058 biosynthetic process; GO:0042340 keratan sulfate catabolic process; GO:0030207 chondroitin sulfate catabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:0030204 chondroitin sulfate metabolic process; GO:0030203 glycosaminoglycan metabolic process; GO:0071704 organic substance metabolic process; GO:0042339 keratan sulfate metabolic process; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0050654 chondroitin sulfate proteoglycan metabolic process; GO:0044248 cellular catabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0006665 sphingolipid metabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006022 aminoglycan metabolic process; GO:0030212 hyaluronan metabolic process; GO:0006629 lipid metabolic process; GO:0006790 sulfur compound metabolic process; GO:1903510 mucopolysaccharide metabolic process; GO:0006023 aminoglycan biosynthetic process; GO:0030214 hyaluronan catabolic process; GO:0044712 single-organism catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006664 glycolipid metabolic process; GO:0009100 glycoprotein metabolic process; GO:0006807 nitrogen compound metabolic process; GO:1901136 carbohydrate derivative catabolic process; GO:0005975 carbohydrate metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0006027 glycosaminoglycan catabolic process; GO:1901575 organic substance catabolic process; GO:1901565 organonitrogen compound catabolic process; GO:0006029 proteoglycan metabolic process; GO:0044710 single-organism metabolic process; GO:0009057 macromolecule catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0044273 sulfur compound catabolic process; GO:0006082 organic acid metabolic process; GO:0009056 catabolic process; GO:0043436 oxoacid metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0043202 lysosomal lumen; GO:0042582 azurophil granule; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0008375 acetylglucosaminyltransferase activity; GO:0046982 protein heterodimerization activity; GO:0016758 transferase activity, transferring hexosyl groups; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016798 hydrolase activity, acting on glycosyl bonds; GO:0046983 protein dimerization activity; GO:0004563 beta-N-acetylhexosaminidase activity; GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds; GO:0008194 UDP-glycosyltransferase activity; GO:0016787 hydrolase activity; GO:0016757 transferase activity, transferring glycosyl groups; GO:0005515 protein binding; GO:0016740 transferase activity; GO:0015929 hexosaminidase activity; ","K12373","HEXA_B; hexosaminidase [EC:3.2.1.52]","hsa04142 Lysosome - Homo sapiens (human); hsa00511 Other glycan degradation - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00603 Glycosphingolipid biosynthesis - globo and isoglobo series - Homo sapiens (human); hsa00604 Glycosphingolipid biosynthesis - ganglio series - Homo sapiens (human); hsa00531 Glycosaminoglycan degradation - Homo sapiens (human); hsa00520 Amino sugar and nucleotide sugar metabolism - Homo sapiens (human); ","IPR029018; IPR015883; IPR029019; IPR017853; IPR013781; ","\"Chitobiase/beta-hexosaminidase domain 2-like; Glycoside hydrolase family 20, catalytic domain; Beta-hexosaminidase, eukaryotic type, N-terminal; Glycoside hydrolase superfamily; Glycoside hydrolase, catalytic domain; \"\r"]
["P07099","Epoxide hydrolase 1 OS=Homo sapiens OX=9606 GN=EPHX1","EPHX1",52.948,102.66,34.3,15,29,15,1.141,1.106,1.176,0.847,0.906,0.883,0.77,0.000584,"endoplasmic reticulum\r","GO:0071466 cellular response to xenobiotic stimulus; GO:0051716 cellular response to stimulus; GO:0014070 response to organic cyclic compound; GO:0006725 cellular aromatic compound metabolic process; GO:0009636 response to toxic substance; GO:0010033 response to organic substance; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0019439 aromatic compound catabolic process; GO:0008152 metabolic process; GO:0042221 response to chemical; GO:0009410 response to xenobiotic stimulus; GO:0006805 xenobiotic metabolic process; GO:0044248 cellular catabolic process; GO:0009056 catabolic process; GO:0009987 cellular process; GO:0070887 cellular response to chemical stimulus; ","GO:0016020 membrane; GO:0043229 intracellular organelle; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044432 endoplasmic reticulum part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; ","GO:0033961 cis-stilbene-oxide hydrolase activity; GO:0016787 hydrolase activity; GO:0016801 hydrolase activity, acting on ether bonds; GO:0004301 epoxide hydrolase activity; GO:0003824 catalytic activity; GO:0016803 ether hydrolase activity; ","K01253","EPHX1; microsomal epoxide hydrolase [EC:3.3.2.9]","hsa04976 Bile secretion - Homo sapiens (human); hsa05204 Chemical carcinogenesis - Homo sapiens (human); hsa00980 Metabolism of xenobiotics by cytochrome P450 - Homo sapiens (human); ","IPR010497; IPR029058; ","\"Epoxide hydrolase, N-terminal; Alpha/Beta hydrolase fold; \"\r"]
["P07108","Acyl-CoA-binding protein OS=Homo sapiens OX=9606 GN=DBI","DBI",10.044,47.98,64.4,7,21,7,1.004,0.976,0.985,1.044,1.005,0.998,1.028,0.171,"cytoplasm\r","GO:0051188 cofactor biosynthetic process; GO:0046470 phosphatidylcholine metabolic process; GO:0046949 fatty-acyl-CoA biosynthetic process; GO:0046486 glycerolipid metabolic process; GO:0035337 fatty-acyl-CoA metabolic process; GO:0044699 single-organism process; GO:0097164 ammonium ion metabolic process; GO:0009058 biosynthetic process; GO:0044255 cellular lipid metabolic process; GO:0036151 phosphatidylcholine acyl-chain remodeling; GO:0044237 cellular metabolic process; GO:0035384 thioester biosynthetic process; GO:0044272 sulfur compound biosynthetic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0006650 glycerophospholipid metabolic process; GO:0009108 coenzyme biosynthetic process; GO:0009987 cellular process; GO:0006629 lipid metabolic process; GO:0006790 sulfur compound metabolic process; GO:0071616 acyl-CoA biosynthetic process; GO:0044763 single-organism cellular process; GO:0035383 thioester metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0006732 coenzyme metabolic process; GO:0035336 long-chain fatty-acyl-CoA metabolic process; GO:0044238 primary metabolic process; GO:0035338 long-chain fatty-acyl-CoA biosynthetic process; GO:1901576 organic substance biosynthetic process; GO:0006637 acyl-CoA metabolic process; GO:0044249 cellular biosynthetic process; GO:0051186 cofactor metabolic process; GO:0006810 transport; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0019637 organophosphate metabolic process; GO:0006644 phospholipid metabolic process; GO:0051179 localization; GO:1901564 organonitrogen compound metabolic process; ","GO:0005788 endoplasmic reticulum lumen; GO:0043229 intracellular organelle; GO:0005783 endoplasmic reticulum; GO:0044421 extracellular region part; GO:0097038 perinuclear endoplasmic reticulum; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0070013 intracellular organelle lumen; GO:0044432 endoplasmic reticulum part; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0005794 Golgi apparatus; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0005102 receptor binding; GO:0000062 fatty-acyl-CoA binding; GO:0005488 binding; GO:0046983 protein dimerization activity; GO:0043167 ion binding; GO:0008289 lipid binding; GO:0036042 long-chain fatty acyl-CoA binding; GO:0005515 protein binding; GO:0043168 anion binding; GO:0030156 benzodiazepine receptor binding; GO:0048037 cofactor binding; GO:1901681 sulfur compound binding; GO:0050662 coenzyme binding; ","K08762","DBI; diazepam-binding inhibitor (GABA receptor modulator, acyl-CoA-binding protein)","hsa03320 PPAR signaling pathway - Homo sapiens (human); ","IPR000582; IPR014352; ","\"Acyl-CoA-binding protein, ACBP; FERM/acyl-CoA-binding protein, 3-helical bundle; \"\r"]
["P07195","L-lactate dehydrogenase B chain OS=Homo sapiens OX=9606 GN=LDHB","LDHB",36.638,106.04,36.8,12,37,11,1.059,1.052,1.071,0.925,0.974,0.971,0.902,0.00412,"cytoplasm\r","GO:0019362 pyridine nucleotide metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:1901615 organic hydroxy compound metabolic process; GO:0046496 nicotinamide nucleotide metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0072524 pyridine-containing compound metabolic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0006090 pyruvate metabolic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0006089 lactate metabolic process; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0006732 coenzyme metabolic process; GO:0044238 primary metabolic process; GO:0005975 carbohydrate metabolic process; GO:0051186 cofactor metabolic process; GO:0006793 phosphorus metabolic process; GO:0019674 NAD metabolic process; GO:0044710 single-organism metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0019637 organophosphate metabolic process; GO:0006082 organic acid metabolic process; GO:0043436 oxoacid metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0098857 membrane microdomain; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0043209 myelin sheath; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0098589 membrane region; GO:1903561 extracellular vesicle; GO:0045121 membrane raft; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0019900 kinase binding; GO:0048037 cofactor binding; GO:0016491 oxidoreductase activity; GO:0016614 oxidoreductase activity, acting on CH-OH group of donors; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0051287 NAD binding; GO:0005488 binding; GO:0004457 lactate dehydrogenase activity; GO:0004459 L-lactate dehydrogenase activity; GO:0019899 enzyme binding; GO:0036094 small molecule binding; GO:0050662 coenzyme binding; ","K00016","LDH; L-lactate dehydrogenase [EC:1.1.1.27]","hsa00640 Propanoate metabolism - Homo sapiens (human); hsa00620 Pyruvate metabolism - Homo sapiens (human); hsa04066 HIF-1 signaling pathway - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00270 Cysteine and methionine metabolism - Homo sapiens (human); hsa04922 Glucagon signaling pathway - Homo sapiens (human); hsa05230 Central carbon metabolism in cancer - Homo sapiens (human); hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human); ","IPR022383; IPR016040; IPR001236; IPR015955; ","\"Lactate/malate dehydrogenase, C-terminal; NAD(P)-binding domain; Lactate/malate dehydrogenase, N-terminal; Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal; \"\r"]
["P07196","Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL","NEFL",61.516,11.653,9.9,6,14,4,1.028,1.052,1.094,0.957,0.914,0.995,0.903,0.0285,"nucleus\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0010941 regulation of cell death; GO:0021766 hippocampus development; GO:0007420 brain development; GO:0043523 regulation of neuron apoptotic process; GO:0032989 cellular component morphogenesis; GO:0021987 cerebral cortex development; GO:0008090 retrograde axonal transport; GO:0046685 response to arsenic-containing substance; GO:0044237 cellular metabolic process; GO:0050877 neurological system process; GO:0051385 response to mineralocorticoid; GO:0021537 telencephalon development; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0065003 macromolecular complex assembly; GO:0044093 positive regulation of molecular function; GO:0032535 regulation of cellular component size; GO:0048545 response to steroid hormone; GO:0009719 response to endogenous stimulus; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:1901652 response to peptide; GO:0008089 anterograde axonal transport; GO:0051412 response to corticosterone; GO:0044765 single-organism transport; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0014070 response to organic cyclic compound; GO:0048699 generation of neurons; GO:0031346 positive regulation of cell projection organization; GO:0033693 neurofilament bundle assembly; GO:0044763 single-organism cellular process; GO:0048812 neuron projection morphogenesis; GO:0032501 multicellular organismal process; GO:0000902 cell morphogenesis; GO:0006810 transport; GO:0000165 MAPK cascade; GO:0000226 microtubule cytoskeleton organization; GO:0010243 response to organonitrogen compound; GO:0034643 establishment of mitochondrion localization, microtubule-mediated; GO:0048513 animal organ development; GO:0051336 regulation of hydrolase activity; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0007417 central nervous system development; GO:0044260 cellular macromolecule metabolic process; GO:1901698 response to nitrogen compound; GO:0006464 cellular protein modification process; GO:0051094 positive regulation of developmental process; GO:0060548 negative regulation of cell death; GO:0097435 supramolecular fiber organization; GO:0010975 regulation of neuron projection development; GO:0051640 organelle localization; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0016310 phosphorylation; GO:0044707 single-multicellular organism process; GO:0046907 intracellular transport; GO:1903935 response to sodium arsenite; GO:0044267 cellular protein metabolic process; GO:1901700 response to oxygen-containing compound; GO:0043067 regulation of programmed cell death; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0045597 positive regulation of cell differentiation; GO:0051239 regulation of multicellular organismal process; GO:0030705 cytoskeleton-dependent intracellular transport; GO:0009653 anatomical structure morphogenesis; GO:0051646 mitochondrion localization; GO:0043524 negative regulation of neuron apoptotic process; GO:1902578 single-organism localization; GO:0051345 positive regulation of hydrolase activity; GO:0051654 establishment of mitochondrion localization; GO:0050772 positive regulation of axonogenesis; GO:0030900 forebrain development; GO:1902580 single-organism cellular localization; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0050885 neuromuscular process controlling balance; GO:0006461 protein complex assembly; GO:0023014 signal transduction by protein phosphorylation; GO:1901215 negative regulation of neuron death; GO:0045104 intermediate filament cytoskeleton organization; GO:0006950 response to stress; GO:0043547 positive regulation of GTPase activity; GO:0048731 system development; GO:0051960 regulation of nervous system development; GO:0060284 regulation of cell development; GO:0045103 intermediate filament-based process; GO:0098930 axonal transport; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0051656 establishment of organelle localization; GO:0007017 microtubule-based process; GO:0050770 regulation of axonogenesis; GO:0030182 neuron differentiation; GO:0048678 response to axon injury; GO:0006793 phosphorus metabolic process; GO:0010976 positive regulation of neuron projection development; GO:0006996 organelle organization; GO:0006928 movement of cell or subcellular component; GO:0050769 positive regulation of neurogenesis; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:1902074 response to salt; GO:0043412 macromolecule modification; GO:0051179 localization; GO:0050905 neuromuscular process; GO:0050793 regulation of developmental process; GO:0045109 intermediate filament organization; GO:0045666 positive regulation of neuron differentiation; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0021761 limbic system development; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0009611 response to wounding; GO:0051130 positive regulation of cellular component organization; GO:0007165 signal transduction; GO:0010970 transport along microtubule; GO:0051649 establishment of localization in cell; GO:0047497 mitochondrion transport along microtubule; GO:0007154 cell communication; GO:0032990 cell part morphogenesis; GO:0022607 cellular component assembly; GO:0032536 regulation of cell projection size; GO:0048858 cell projection morphogenesis; GO:0060322 head development; GO:0010035 response to inorganic substance; GO:0010720 positive regulation of cell development; GO:0060052 neurofilament cytoskeleton organization; GO:0019896 axonal transport of mitochondrion; GO:0032502 developmental process; GO:0071822 protein complex subunit organization; GO:0021510 spinal cord development; GO:0009636 response to toxic substance; GO:0051962 positive regulation of nervous system development; GO:0048522 positive regulation of cellular process; GO:0031102 neuron projection regeneration; GO:0023052 signaling; GO:0051384 response to glucocorticoid; GO:1902582 single-organism intracellular transport; GO:1902589 single-organism organelle organization; GO:0008088 axo-dendritic transport; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0043434 response to peptide hormone; GO:0030030 cell projection organization; GO:0045664 regulation of neuron differentiation; GO:0051258 protein polymerization; GO:0043087 regulation of GTPase activity; GO:0065009 regulation of molecular function; GO:0040011 locomotion; GO:0070271 protein complex biogenesis; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0021543 pallium development; GO:0072384 organelle transport along microtubule; GO:0016043 cellular component organization; GO:0043069 negative regulation of programmed cell death; GO:0010770 positive regulation of cell morphogenesis involved in differentiation; GO:0031344 regulation of cell projection organization; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0099111 microtubule-based transport; GO:0071704 organic substance metabolic process; GO:0031103 axon regeneration; GO:0045110 intermediate filament bundle assembly; GO:0033993 response to lipid; GO:0030154 cell differentiation; GO:0006468 protein phosphorylation; GO:0043066 negative regulation of apoptotic process; GO:0031133 regulation of axon diameter; GO:0031960 response to corticosteroid; GO:0009987 cellular process; GO:1901214 regulation of neuron death; GO:0043623 cellular protein complex assembly; GO:0045595 regulation of cell differentiation; GO:0034622 cellular macromolecular complex assembly; GO:0003008 system process; GO:0035556 intracellular signal transduction; GO:1903937 response to acrylamide; GO:0045105 intermediate filament polymerization or depolymerization; GO:0031175 neuron projection development; GO:0048518 positive regulation of biological process; GO:0043933 macromolecular complex subunit organization; GO:0043085 positive regulation of catalytic activity; GO:0051641 cellular localization; GO:0061564 axon development; GO:0007018 microtubule-based movement; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0090066 regulation of anatomical structure size; GO:0014012 peripheral nervous system axon regeneration; GO:0051128 regulation of cellular component organization; GO:0031099 regeneration; GO:0009725 response to hormone; GO:0022604 regulation of cell morphogenesis; GO:0042981 regulation of apoptotic process; GO:1901654 response to ketone; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:0050767 regulation of neurogenesis; ","GO:0099568 cytoplasmic region; GO:0005737 cytoplasm; GO:0032838 cell projection cytoplasm; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0030426 growth cone; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0043209 myelin sheath; GO:0043005 neuron projection; GO:0005883 neurofilament; GO:0097458 neuron part; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0099513 polymeric cytoskeletal fiber; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0030427 site of polarized growth; GO:0044463 cell projection part; GO:0005829 cytosol; GO:0033267 axon part; GO:0099081 supramolecular polymer; GO:0043226 organelle; GO:0030424 axon; GO:1904115 axon cytoplasm; GO:0045111 intermediate filament cytoskeleton; GO:0005882 intermediate filament; GO:0044444 cytoplasmic part; ","GO:0030674 protein binding, bridging; GO:0046982 protein heterodimerization activity; GO:0043274 phospholipase binding; GO:0005085 guanyl-nucleotide exchange factor activity; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0042802 identical protein binding; GO:0005200 structural constituent of cytoskeleton; GO:0005488 binding; GO:0019904 protein domain specific binding; GO:0060090 binding, bridging; GO:0008022 protein C-terminus binding; GO:0005088 Ras guanyl-nucleotide exchange factor activity; GO:0005198 structural molecule activity; GO:0019899 enzyme binding; ","K04572","NEFL; neurofilament light polypeptide","hsa05014 Amyotrophic lateral sclerosis (ALS) - Homo sapiens (human); ","IPR006821; ","\"Intermediate filament head, DNA-binding domain; \"\r"]
["P07203","Glutathione peroxidase 1 OS=Homo sapiens OX=9606 GN=GPX1","GPX1",22.088,79.973,57.1,10,19,10,1.021,1.116,1.091,0.925,0.942,0.952,0.873,0.00854,"extracellular\r","GO:0044700 single organism signaling; GO:0090130 tissue migration; GO:0010941 regulation of cell death; GO:0090201 negative regulation of release of cytochrome c from mitochondria; GO:0043523 regulation of neuron apoptotic process; GO:0044255 cellular lipid metabolic process; GO:0031347 regulation of defense response; GO:0044237 cellular metabolic process; GO:0010821 regulation of mitochondrion organization; GO:0009607 response to biotic stimulus; GO:0010466 negative regulation of peptidase activity; GO:0008152 metabolic process; GO:0001525 angiogenesis; GO:0006639 acylglycerol metabolic process; GO:0098869 cellular oxidant detoxification; GO:0018158 protein oxidation; GO:0052548 regulation of endopeptidase activity; GO:0051716 cellular response to stimulus; GO:0002064 epithelial cell development; GO:0009609 response to symbiotic bacterium; GO:0080090 regulation of primary metabolic process; GO:0060537 muscle tissue development; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0048870 cell motility; GO:0043086 negative regulation of catalytic activity; GO:0035296 regulation of tube diameter; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0009650 UV protection; GO:0019439 aromatic compound catabolic process; GO:1901575 organic substance catabolic process; GO:1902532 negative regulation of intracellular signal transduction; GO:0080135 regulation of cellular response to stress; GO:0061136 regulation of proteasomal protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:1902905 positive regulation of supramolecular fiber organization; GO:0060548 negative regulation of cell death; GO:0043436 oxoacid metabolic process; GO:0030855 epithelial cell differentiation; GO:0055001 muscle cell development; GO:0072359 circulatory system development; GO:0044707 single-multicellular organism process; GO:0097190 apoptotic signaling pathway; GO:0050880 regulation of blood vessel size; GO:0050728 negative regulation of inflammatory response; GO:1901700 response to oxygen-containing compound; GO:0003018 vascular process in circulatory system; GO:0048519 negative regulation of biological process; GO:0044270 cellular nitrogen compound catabolic process; GO:0009653 anatomical structure morphogenesis; GO:0042743 hydrogen peroxide metabolic process; GO:1990748 cellular detoxification; GO:0023057 negative regulation of signaling; GO:0046483 heterocycle metabolic process; GO:0009410 response to xenobiotic stimulus; GO:0010648 negative regulation of cell communication; GO:0006139 nucleobase-containing compound metabolic process; GO:0044248 cellular catabolic process; GO:0061061 muscle structure development; GO:0051702 interaction with symbiont; GO:0042176 regulation of protein catabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0035150 regulation of tube size; GO:0042744 hydrogen peroxide catabolic process; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0006638 neutral lipid metabolic process; GO:0045861 negative regulation of proteolysis; GO:0033599 regulation of mammary gland epithelial cell proliferation; GO:0009416 response to light stimulus; GO:0006950 response to stress; GO:0032101 regulation of response to external stimulus; GO:0008283 cell proliferation; GO:0006163 purine nucleotide metabolic process; GO:1900408 negative regulation of cellular response to oxidative stress; GO:0042542 response to hydrogen peroxide; GO:0019637 organophosphate metabolic process; GO:0048589 developmental growth; GO:0043412 macromolecule modification; GO:0040007 growth; GO:0046486 glycerolipid metabolic process; GO:0048747 muscle fiber development; GO:0033194 response to hydroperoxide; GO:0051674 localization of cell; GO:0009968 negative regulation of signal transduction; GO:0001568 blood vessel development; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0045446 endothelial cell differentiation; GO:0006796 phosphate-containing compound metabolic process; GO:0097746 regulation of blood vessel diameter; GO:0009611 response to wounding; GO:0007165 signal transduction; GO:0006915 apoptotic process; GO:0050777 negative regulation of immune response; GO:0019372 lipoxygenase pathway; GO:0006629 lipid metabolic process; GO:2000116 regulation of cysteine-type endopeptidase activity; GO:0055114 oxidation-reduction process; GO:0009636 response to toxic substance; GO:0001944 vasculature development; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0007517 muscle organ development; GO:0001667 ameboidal-type cell migration; GO:2001236 regulation of extrinsic apoptotic signaling pathway; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0036211 protein modification process; GO:0098754 detoxification; GO:0014706 striated muscle tissue development; GO:0016477 cell migration; GO:0043069 negative regulation of programmed cell death; GO:0043534 blood vessel endothelial cell migration; GO:0046434 organophosphate catabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0010332 response to gamma radiation; GO:1903201 regulation of oxidative stress-induced cell death; GO:0097193 intrinsic apoptotic signaling pathway; GO:0051707 response to other organism; GO:0051346 negative regulation of hydrolase activity; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:0006575 cellular modified amino acid metabolic process; GO:0072593 reactive oxygen species metabolic process; GO:0043066 negative regulation of apoptotic process; GO:0023056 positive regulation of signaling; GO:0008015 blood circulation; GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors; GO:0034641 cellular nitrogen compound metabolic process; GO:0010647 positive regulation of cell communication; GO:0031348 negative regulation of defense response; GO:0051146 striated muscle cell differentiation; GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway; GO:0097755 positive regulation of blood vessel diameter; GO:0035556 intracellular signal transduction; GO:0014904 myotube cell development; GO:0033043 regulation of organelle organization; GO:0042311 vasodilation; GO:1902176 negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway; GO:0040029 regulation of gene expression, epigenetic; GO:0051450 myoblast proliferation; GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress; GO:1901565 organonitrogen compound catabolic process; GO:1900407 regulation of cellular response to oxidative stress; GO:0008219 cell death; GO:0050727 regulation of inflammatory response; GO:0019752 carboxylic acid metabolic process; GO:0042692 muscle cell differentiation; GO:0051248 negative regulation of protein metabolic process; GO:0031099 regeneration; GO:0009056 catabolic process; GO:0042981 regulation of apoptotic process; GO:0065008 regulation of biological quality; GO:0006518 peptide metabolic process; GO:0060055 angiogenesis involved in wound healing; GO:0051896 regulation of protein kinase B signaling; GO:0050877 neurological system process; GO:0009605 response to external stimulus; GO:0043542 endothelial cell migration; GO:0006195 purine nucleotide catabolic process; GO:0050678 regulation of epithelial cell proliferation; GO:0032102 negative regulation of response to external stimulus; GO:0032787 monocarboxylic acid metabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:1903362 regulation of cellular protein catabolic process; GO:0006690 icosanoid metabolic process; GO:0006790 sulfur compound metabolic process; GO:0001659 temperature homeostasis; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0044281 small molecule metabolic process; GO:0009166 nucleotide catabolic process; GO:0000302 response to reactive oxygen species; GO:0072521 purine-containing compound metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0060538 skeletal muscle organ development; GO:0032501 multicellular organismal process; GO:0048513 animal organ development; GO:0055002 striated muscle cell development; GO:0051336 regulation of hydrolase activity; GO:0010631 epithelial cell migration; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:1903202 negative regulation of oxidative stress-induced cell death; GO:0002682 regulation of immune system process; GO:0006464 cellular protein modification process; GO:0003015 heart process; GO:0003013 circulatory system process; GO:1902903 regulation of supramolecular fiber organization; GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0010951 negative regulation of endopeptidase activity; GO:0042127 regulation of cell proliferation; GO:0009628 response to abiotic stimulus; GO:0045454 cell redox homeostasis; GO:0043067 regulation of programmed cell death; GO:0044267 cellular protein metabolic process; GO:0048523 negative regulation of cellular process; GO:0090132 epithelium migration; GO:0072523 purine-containing compound catabolic process; GO:0080134 regulation of response to stress; GO:0051239 regulation of multicellular organismal process; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:0009617 response to bacterium; GO:0010823 negative regulation of mitochondrion organization; GO:1902531 regulation of intracellular signal transduction; GO:0048731 system development; GO:0036473 cell death in response to oxidative stress; GO:0072358 cardiovascular system development; GO:2001237 negative regulation of extrinsic apoptotic signaling pathway; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0010269 response to selenium ion; GO:0009892 negative regulation of metabolic process; GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; GO:0003158 endothelium development; GO:0006641 triglyceride metabolic process; GO:0006793 phosphorus metabolic process; GO:0001885 endothelial cell development; GO:0048741 skeletal muscle fiber development; GO:0002862 negative regulation of inflammatory response to antigenic stimulus; GO:0006928 movement of cell or subcellular component; GO:0007605 sensory perception of sound; GO:0012501 programmed cell death; GO:1902882 regulation of response to oxidative stress; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:0050793 regulation of developmental process; GO:1901564 organonitrogen compound metabolic process; GO:0014902 myotube differentiation; GO:0090199 regulation of release of cytochrome c from mitochondria; GO:0009117 nucleotide metabolic process; GO:0051129 negative regulation of cellular component organization; GO:1902533 positive regulation of intracellular signal transduction; GO:1901568 fatty acid derivative metabolic process; GO:0048871 multicellular organismal homeostasis; GO:0051130 positive regulation of cellular component organization; GO:2001233 regulation of apoptotic signaling pathway; GO:1901292 nucleoside phosphate catabolic process; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:2001243 negative regulation of intrinsic apoptotic signaling pathway; GO:0006753 nucleoside phosphate metabolic process; GO:0006979 response to oxidative stress; GO:1901361 organic cyclic compound catabolic process; GO:0006749 glutathione metabolic process; GO:0009314 response to radiation; GO:0048514 blood vessel morphogenesis; GO:0034599 cellular response to oxidative stress; GO:0010035 response to inorganic substance; GO:0007519 skeletal muscle tissue development; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0010468 regulation of gene expression; GO:0007600 sensory perception; GO:0009888 tissue development; GO:0009608 response to symbiont; GO:0042246 tissue regeneration; GO:0019725 cellular homeostasis; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0043603 cellular amide metabolic process; GO:0002683 negative regulation of immune system process; GO:0010639 negative regulation of organelle organization; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:1902883 negative regulation of response to oxidative stress; GO:0019222 regulation of metabolic process; GO:0045444 fat cell differentiation; GO:0040011 locomotion; GO:0052547 regulation of peptidase activity; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:0050954 sensory perception of mechanical stimulus; GO:2000026 regulation of multicellular organismal development; GO:0006725 cellular aromatic compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0048468 cell development; GO:2000117 negative regulation of cysteine-type endopeptidase activity; GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0060047 heart contraction; GO:0009987 cellular process; GO:1901214 regulation of neuron death; GO:0051897 positive regulation of protein kinase B signaling; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0043403 skeletal muscle tissue regeneration; GO:0003008 system process; GO:0044712 single-organism catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0048585 negative regulation of response to stimulus; GO:0006631 fatty acid metabolic process; GO:0048518 positive regulation of biological process; GO:0010212 response to ionizing radiation; GO:0009411 response to UV; GO:0042060 wound healing; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:2001242 regulation of intrinsic apoptotic signaling pathway; GO:0090066 regulation of anatomical structure size; GO:0051128 regulation of cellular component organization; GO:0009967 positive regulation of signal transduction; GO:0002861 regulation of inflammatory response to antigenic stimulus; GO:0065007 biological regulation; GO:0046700 heterocycle catabolic process; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0044429 mitochondrial part; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0004602 glutathione peroxidase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016209 antioxidant activity; GO:0019904 protein domain specific binding; GO:0005515 protein binding; GO:0004601 peroxidase activity; GO:0017124 SH3 domain binding; GO:0016684 oxidoreductase activity, acting on peroxide as acceptor; GO:0016491 oxidoreductase activity; ","K00432","gpx; glutathione peroxidase [EC:1.11.1.9]","hsa00480 Glutathione metabolism - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04918 Thyroid hormone synthesis - Homo sapiens (human); hsa05014 Amyotrophic lateral sclerosis (ALS) - Homo sapiens (human); hsa00590 Arachidonic acid metabolism - Homo sapiens (human); ","IPR012336; ","Thioredoxin-like fold; \r"]
["P07204","Thrombomodulin OS=Homo sapiens OX=9606 GN=THBD","THBD",60.329,5.4074,3.1,2,2,2,1.118,0.954,0.992,1.01,0.871,1.067,0.962,0.632,"plasma membrane\r","GO:0044700 single organism signaling; GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0051674 localization of cell; GO:0022414 reproductive process; GO:0046683 response to organophosphorus; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0009607 response to biotic stimulus; GO:0009611 response to wounding; GO:0009605 response to external stimulus; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0051240 positive regulation of multicellular organismal process; GO:0044706 multi-multicellular organism process; GO:0032102 negative regulation of response to external stimulus; GO:0032103 positive regulation of response to external stimulus; GO:1900046 regulation of hemostasis; GO:0009719 response to endogenous stimulus; GO:0090303 positive regulation of wound healing; GO:0009314 response to radiation; GO:0030194 positive regulation of blood coagulation; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0002237 response to molecule of bacterial origin; GO:0044763 single-organism cellular process; GO:0048870 cell motility; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:1903035 negative regulation of response to wounding; GO:0051704 multi-organism process; GO:0010243 response to organonitrogen compound; GO:0050900 leukocyte migration; GO:0050865 regulation of cell activation; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0051591 response to cAMP; GO:1900048 positive regulation of hemostasis; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0040011 locomotion; GO:0050817 coagulation; GO:1903036 positive regulation of response to wounding; GO:0050794 regulation of cellular process; GO:0000003 reproduction; GO:0016477 cell migration; GO:0044707 single-multicellular organism process; GO:0009628 response to abiotic stimulus; GO:0051918 negative regulation of fibrinolysis; GO:0010543 regulation of platelet activation; GO:1901700 response to oxygen-containing compound; GO:0030193 regulation of blood coagulation; GO:0043207 response to external biotic stimulus; GO:0048519 negative regulation of biological process; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0007599 hemostasis; GO:0051239 regulation of multicellular organismal process; GO:0050866 negative regulation of cell activation; GO:1900047 negative regulation of hemostasis; GO:0033993 response to lipid; GO:0007565 female pregnancy; GO:0014074 response to purine-containing compound; GO:0009987 cellular process; GO:0009617 response to bacterium; GO:0050878 regulation of body fluid levels; GO:0006950 response to stress; GO:0032496 response to lipopolysaccharide; GO:0051917 regulation of fibrinolysis; GO:0010544 negative regulation of platelet activation; GO:0002376 immune system process; GO:0032101 regulation of response to external stimulus; GO:0050820 positive regulation of coagulation; GO:0010033 response to organic substance; GO:0048585 negative regulation of response to stimulus; GO:0048518 positive regulation of biological process; GO:0061045 negative regulation of wound healing; GO:0050818 regulation of coagulation; GO:0030195 negative regulation of blood coagulation; GO:0010165 response to X-ray; GO:0010212 response to ionizing radiation; GO:0042060 wound healing; GO:0061041 regulation of wound healing; GO:0044703 multi-organism reproductive process; GO:0006928 movement of cell or subcellular component; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:1903034 regulation of response to wounding; GO:0050819 negative regulation of coagulation; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0031226 intrinsic component of plasma membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0098588 bounding membrane of organelle; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0016327 apicolateral plasma membrane; GO:0098590 plasma membrane region; GO:0044459 plasma membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0044437 vacuolar part; GO:0098805 whole membrane; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0009986 cell surface; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0038023 signaling receptor activity; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0005488 binding; GO:0043167 ion binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0005509 calcium ion binding; GO:0004888 transmembrane signaling receptor activity; GO:0004871 signal transducer activity; GO:0099600 transmembrane receptor activity; ","K03907","THBD; thrombomodulin","hsa04610 Complement and coagulation cascades - Homo sapiens (human); hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human); hsa04933 AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human); ","IPR015149; IPR016187; IPR001881; IPR000742; IPR009030; IPR016186; IPR001304; IPR026823; ","\"Thrombomodulin-like, EGF-like; C-type lectin fold; EGF-like calcium-binding domain; EGF-like domain; Growth factor receptor cysteine-rich domain; C-type lectin-like/link domain; C-type lectin-like; Complement Clr-like EGF domain; \"\r"]
["P07225","Vitamin K-dependent protein S OS=Homo sapiens OX=9606 GN=PROS1","PROS1",75.122,34.947,10.4,6,9,6,0.896,0.891,0.859,1.085,1.067,1.126,1.239,0.000496,"extracellular\r","GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0006518 peptide metabolic process; GO:0051674 localization of cell; GO:0006465 signal peptide processing; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0016485 protein processing; GO:0031347 regulation of defense response; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:0042730 fibrinolysis; GO:0009611 response to wounding; GO:0010466 negative regulation of peptidase activity; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0032102 negative regulation of response to external stimulus; GO:1900046 regulation of hemostasis; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0002697 regulation of immune effector process; GO:0017187 peptidyl-glutamic acid carboxylation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0052548 regulation of endopeptidase activity; GO:0010468 regulation of gene expression; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0048870 cell motility; GO:0043603 cellular amide metabolic process; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0010605 negative regulation of macromolecule metabolic process; GO:1903035 negative regulation of response to wounding; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0050900 leukocyte migration; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:0032940 secretion by cell; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0018200 peptidyl-glutamic acid modification; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0006464 cellular protein modification process; GO:0044092 negative regulation of molecular function; GO:0002682 regulation of immune system process; GO:0040011 locomotion; GO:0050817 coagulation; GO:1903317 regulation of protein maturation; GO:0036211 protein modification process; GO:0052547 regulation of peptidase activity; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0016477 cell migration; GO:0030449 regulation of complement activation; GO:0044707 single-multicellular organism process; GO:2000257 regulation of protein activation cascade; GO:0010951 negative regulation of endopeptidase activity; GO:0060255 regulation of macromolecule metabolic process; GO:0030193 regulation of blood coagulation; GO:0002920 regulation of humoral immune response; GO:0044267 cellular protein metabolic process; GO:0048193 Golgi vesicle transport; GO:0002576 platelet degranulation; GO:0002673 regulation of acute inflammatory response; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:0051346 negative regulation of hydrolase activity; GO:0007599 hemostasis; GO:0071704 organic substance metabolic process; GO:1900047 negative regulation of hemostasis; GO:1902578 single-organism localization; GO:0006508 proteolysis; GO:0034641 cellular nitrogen compound metabolic process; GO:0009987 cellular process; GO:0018214 protein carboxylation; GO:0045861 negative regulation of proteolysis; GO:0050878 regulation of body fluid levels; GO:0006950 response to stress; GO:0016192 vesicle-mediated transport; GO:0006807 nitrogen compound metabolic process; GO:0002376 immune system process; GO:0032101 regulation of response to external stimulus; GO:0048585 negative regulation of response to stimulus; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0061045 negative regulation of wound healing; GO:0009892 negative regulation of metabolic process; GO:0051641 cellular localization; GO:0018193 peptidyl-amino acid modification; GO:0050818 regulation of coagulation; GO:0030195 negative regulation of blood coagulation; GO:0045055 regulated exocytosis; GO:0061041 regulation of wound healing; GO:0042060 wound healing; GO:0051246 regulation of protein metabolic process; GO:0050727 regulation of inflammatory response; GO:0070613 regulation of protein processing; GO:0006928 movement of cell or subcellular component; GO:0051248 negative regulation of protein metabolic process; GO:0010467 gene expression; GO:0043412 macromolecule modification; GO:0051179 localization; GO:0051604 protein maturation; GO:0006888 ER to Golgi vesicle-mediated transport; GO:1903034 regulation of response to wounding; GO:0050819 negative regulation of coagulation; GO:0006887 exocytosis; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0005796 Golgi lumen; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0072562 blood microparticle; GO:0060205 cytoplasmic vesicle lumen; GO:0044432 endoplasmic reticulum part; GO:0031093 platelet alpha granule lumen; GO:0031091 platelet alpha granule; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0043167 ion binding; GO:0030414 peptidase inhibitor activity; GO:0061134 peptidase regulator activity; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0061135 endopeptidase regulator activity; GO:0005509 calcium ion binding; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0004866 endopeptidase inhibitor activity; ","K03908","PROS1; protein S","hsa04610 Complement and coagulation cascades - Homo sapiens (human); ","IPR017857; IPR000294; IPR001881; IPR000742; IPR009030; IPR013320; IPR001791; ","\"Coagulation factor, subgroup, Gla domain; Gamma-carboxyglutamic acid-rich (GLA) domain; EGF-like calcium-binding domain; EGF-like domain; Growth factor receptor cysteine-rich domain; Concanavalin A-like lectin/glucanase domain; Laminin G domain; \"\r"]
["P07237","Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB","P4HB",57.116,204.64,53.9,33,92,33,0.99,0.987,0.973,1.014,1.03,1.019,1.038,0.006,"extracellular\r","GO:0065008 regulation of biological quality; GO:0010941 regulation of cell death; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0042157 lipoprotein metabolic process; GO:0006457 protein folding; GO:2001233 regulation of apoptotic signaling pathway; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0010646 regulation of cell communication; GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline; GO:0006979 response to oxidative stress; GO:0046596 regulation of viral entry into host cell; GO:0019471 4-hydroxyproline metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0042158 lipoprotein biosynthetic process; GO:0070887 cellular response to chemical stimulus; GO:1903902 positive regulation of viral life cycle; GO:0051716 cellular response to stimulus; GO:0043902 positive regulation of multi-organism process; GO:0044281 small molecule metabolic process; GO:0000302 response to reactive oxygen species; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0019725 cellular homeostasis; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0080135 regulation of cellular response to stress; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0006082 organic acid metabolic process; GO:0036211 protein modification process; GO:0043436 oxoacid metabolic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0034976 response to endoplasmic reticulum stress; GO:0009628 response to abiotic stimulus; GO:0045454 cell redox homeostasis; GO:0043067 regulation of programmed cell death; GO:1901700 response to oxygen-containing compound; GO:0044267 cellular protein metabolic process; GO:1903201 regulation of oxidative stress-induced cell death; GO:0080134 regulation of response to stress; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0006575 cellular modified amino acid metabolic process; GO:0046598 positive regulation of viral entry into host cell; GO:0001666 response to hypoxia; GO:0070482 response to oxygen levels; GO:0009059 macromolecule biosynthetic process; GO:0071453 cellular response to oxygen levels; GO:0009987 cellular process; GO:0009966 regulation of signal transduction; GO:0018126 protein hydroxylation; GO:0071456 cellular response to hypoxia; GO:0019511 peptidyl-proline hydroxylation; GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway; GO:1902531 regulation of intracellular signal transduction; GO:0006950 response to stress; GO:0043900 regulation of multi-organism process; GO:0050792 regulation of viral process; GO:0006807 nitrogen compound metabolic process; GO:0018208 peptidyl-proline modification; GO:0044238 primary metabolic process; GO:1901605 alpha-amino acid metabolic process; GO:1901576 organic substance biosynthetic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0018193 peptidyl-amino acid modification; GO:0034645 cellular macromolecule biosynthetic process; GO:0048524 positive regulation of viral process; GO:1900407 regulation of cellular response to oxidative stress; GO:2001242 regulation of intrinsic apoptotic signaling pathway; GO:0019752 carboxylic acid metabolic process; GO:1902882 regulation of response to oxidative stress; GO:0036293 response to decreased oxygen levels; GO:1903900 regulation of viral life cycle; GO:0043412 macromolecule modification; GO:0036294 cellular response to decreased oxygen levels; GO:0042981 regulation of apoptotic process; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0009897 external side of plasma membrane; GO:0031410 cytoplasmic vesicle; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0048770 pigment granule; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0005925 focal adhesion; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0098552 side of membrane; GO:0043229 intracellular organelle; GO:0005788 endoplasmic reticulum lumen; GO:0097708 intracellular vesicle; GO:0042470 melanosome; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0012505 endomembrane system; GO:0034663 endoplasmic reticulum chaperone complex; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0031012 extracellular matrix; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0044432 endoplasmic reticulum part; GO:0016222 procollagen-proline 4-dioxygenase complex; GO:0005793 endoplasmic reticulum-Golgi intermediate compartment; GO:1990204 oxidoreductase complex; GO:0009986 cell surface; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0003723 RNA binding; GO:0046982 protein heterodimerization activity; GO:0005102 receptor binding; GO:0031543 peptidyl-proline dioxygenase activity; GO:0044877 macromolecular complex binding; GO:0046983 protein dimerization activity; GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; GO:0005178 integrin binding; GO:0005515 protein binding; GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; GO:0004656 procollagen-proline 4-dioxygenase activity; GO:0003756 protein disulfide isomerase activity; GO:0016491 oxidoreductase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds; GO:0050839 cell adhesion molecule binding; GO:0016853 isomerase activity; GO:0003824 catalytic activity; GO:0019798 procollagen-proline dioxygenase activity; GO:0005488 binding; GO:0051213 dioxygenase activity; GO:0003676 nucleic acid binding; GO:0016860 intramolecular oxidoreductase activity; GO:0031545 peptidyl-proline 4-dioxygenase activity; GO:0019899 enzyme binding; GO:0032403 protein complex binding; ","K09580","PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]","hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); ","IPR005788; IPR012336; IPR013766; ","Disulphide isomerase; Thioredoxin-like fold; Thioredoxin domain; \r"]
["P07305","Histone H1.0 OS=Homo sapiens OX=9606 GN=H1F0","H1F0",20.863,23.009,20.6,4,7,4,1.174,1.115,1.131,0.824,0.885,0.836,0.744,0.000378,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0016043 cellular component organization; GO:0034728 nucleosome organization; GO:0006308 DNA catabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0006259 DNA metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0006309 apoptotic DNA fragmentation; GO:0044270 cellular nitrogen compound catabolic process; GO:0008152 metabolic process; GO:0006323 DNA packaging; GO:0046483 heterocycle metabolic process; GO:0006334 nucleosome assembly; GO:0006139 nucleobase-containing compound metabolic process; GO:0030262 apoptotic nuclear changes; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0006915 apoptotic process; GO:0044248 cellular catabolic process; GO:1901361 organic cyclic compound catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0031497 chromatin assembly; GO:0009987 cellular process; GO:0071824 protein-DNA complex subunit organization; GO:0071103 DNA conformation change; GO:0006333 chromatin assembly or disassembly; GO:0034622 cellular macromolecular complex assembly; GO:0044265 cellular macromolecule catabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0006921 cellular component disassembly involved in execution phase of apoptosis; GO:0044238 primary metabolic process; GO:0000737 DNA catabolic process, endonucleolytic; GO:0043933 macromolecular complex subunit organization; GO:0065004 protein-DNA complex assembly; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0090304 nucleic acid metabolic process; GO:0051276 chromosome organization; GO:0008219 cell death; GO:0006996 organelle organization; GO:0009057 macromolecule catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0022411 cellular component disassembly; GO:0097194 execution phase of apoptosis; GO:0012501 programmed cell death; GO:0006325 chromatin organization; GO:0090305 nucleic acid phosphodiester bond hydrolysis; GO:0009056 catabolic process; GO:0046700 heterocycle catabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044454 nuclear chromosome part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005694 chromosome; GO:0000790 nuclear chromatin; GO:0043227 membrane-bounded organelle; GO:0044815 DNA packaging complex; GO:0032993 protein-DNA complex; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0000791 euchromatin; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0015629 actin cytoskeleton; GO:0000786 nucleosome; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0000785 chromatin; GO:0000228 nuclear chromosome; GO:0005794 Golgi apparatus; GO:0005719 nuclear euchromatin; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003677 DNA binding; GO:0003723 RNA binding; GO:0005515 protein binding; GO:0003682 chromatin binding; GO:0031490 chromatin DNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; ","K11275",null,null,"IPR011991; IPR005818; ","\"Winged helix-turn-helix DNA-binding domain; Linker histone H1/H5, domain H15; \"\r"]
["P07339","Cathepsin D OS=Homo sapiens OX=9606 GN=CTSD","CTSD",44.552,128.62,37.1,13,44,13,0.924,0.946,0.924,1.044,1.054,1.106,1.147,0.00218,"extracellular\r","GO:0044707 single-multicellular organism process; GO:0045321 leukocyte activation; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0044236 multicellular organism metabolic process; GO:0044699 single-organism process; GO:0006914 autophagy; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0051234 establishment of localization; GO:0044243 multicellular organismal catabolic process; GO:0008152 metabolic process; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0044248 cellular catabolic process; GO:0006508 proteolysis; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0036230 granulocyte activation; GO:0044259 multicellular organismal macromolecule metabolic process; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0009987 cellular process; GO:0030574 collagen catabolic process; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0002274 myeloid leukocyte activation; GO:0002443 leukocyte mediated immunity; GO:0044712 single-organism catabolic process; GO:0048002 antigen processing and presentation of peptide antigen; GO:0016192 vesicle-mediated transport; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:0043312 neutrophil degranulation; GO:0032501 multicellular organismal process; GO:0002495 antigen processing and presentation of peptide antigen via MHC class II; GO:0002263 cell activation involved in immune response; GO:0002444 myeloid leukocyte mediated immunity; GO:0002366 leukocyte activation involved in immune response; GO:0006810 transport; GO:0019882 antigen processing and presentation; GO:0019884 antigen processing and presentation of exogenous antigen; GO:1901575 organic substance catabolic process; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; GO:0044710 single-organism metabolic process; GO:0030163 protein catabolic process; GO:0032940 secretion by cell; GO:0009057 macromolecule catabolic process; GO:0032963 collagen metabolic process; GO:0001775 cell activation; GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II; GO:0043299 leukocyte degranulation; GO:0006955 immune response; GO:0051179 localization; GO:0009056 catabolic process; GO:0006887 exocytosis; ","GO:0016020 membrane; GO:0034774 secretory granule lumen; GO:1904724 tertiary granule lumen; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0098857 membrane microdomain; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0048770 pigment granule; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:0098589 membrane region; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0045121 membrane raft; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0042470 melanosome; GO:0070820 tertiary granule; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0043202 lysosomal lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0035580 specific granule lumen; GO:0042581 specific granule; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0004252 serine-type endopeptidase activity; GO:0004175 endopeptidase activity; GO:0008233 peptidase activity; GO:0017171 serine hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0004190 aspartic-type endopeptidase activity; GO:0008236 serine-type peptidase activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0008234 cysteine-type peptidase activity; GO:0070001 aspartic-type peptidase activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0004197 cysteine-type endopeptidase activity; ","K01379","CTSD; cathepsin D [EC:3.4.23.5]","hsa04142 Lysosome - Homo sapiens (human); hsa05152 Tuberculosis - Homo sapiens (human); hsa04071 Sphingolipid signaling pathway - Homo sapiens (human); hsa04210 Apoptosis - Homo sapiens (human); hsa04915 Estrogen signaling pathway - Homo sapiens (human); hsa04140 Autophagy - animal - Homo sapiens (human); ","IPR012848; IPR021109; IPR033121; ","\"Aspartic peptidase, N-terminal; Aspartic peptidase domain; Peptidase family A1 domain; \"\r"]
["P07355","Annexin A2 OS=Homo sapiens OX=9606 GN=ANXA2","ANXA2",38.604,323.31,72.3,31,191,31,1.096,1.107,1.084,0.905,0.912,0.901,0.827,1.55e-05,"cytoplasm\r","GO:0060627 regulation of vesicle-mediated transport; GO:2000273 positive regulation of receptor activity; GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0032270 positive regulation of cellular protein metabolic process; GO:0032371 regulation of sterol transport; GO:0030199 collagen fibril organization; GO:0090002 establishment of protein localization to plasma membrane; GO:0031338 regulation of vesicle fusion; GO:0015031 protein transport; GO:0010469 regulation of receptor activity; GO:0048145 regulation of fibroblast proliferation; GO:0042730 fibrinolysis; GO:0022610 biological adhesion; GO:0001525 angiogenesis; GO:0032379 positive regulation of intracellular lipid transport; GO:0048146 positive regulation of fibroblast proliferation; GO:0061515 myeloid cell development; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0065003 macromolecular complex assembly; GO:0044093 positive regulation of molecular function; GO:0032102 negative regulation of response to external stimulus; GO:1905600 regulation of receptor-mediated endocytosis involved in cholesterol transport; GO:0007155 cell adhesion; GO:0009719 response to endogenous stimulus; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0008104 protein localization; GO:0051099 positive regulation of binding; GO:1903362 regulation of cellular protein catabolic process; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0042325 regulation of phosphorylation; GO:0002443 leukocyte mediated immunity; GO:0051174 regulation of phosphorus metabolic process; GO:0072657 protein localization to membrane; GO:0048259 regulation of receptor-mediated endocytosis; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0032385 positive regulation of intracellular cholesterol transport; GO:0010988 regulation of low-density lipoprotein particle clearance; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0002520 immune system development; GO:0007009 plasma membrane organization; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:0051291 protein heterooligomerization; GO:0048513 animal organ development; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0048583 regulation of response to stimulus; GO:0010604 positive regulation of macromolecule metabolic process; GO:0097435 supramolecular fiber organization; GO:0072359 circulatory system development; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0044707 single-multicellular organism process; GO:0072661 protein targeting to plasma membrane; GO:0030316 osteoclast differentiation; GO:0002283 neutrophil activation involved in immune response; GO:0042127 regulation of cell proliferation; GO:0031399 regulation of protein modification process; GO:0030193 regulation of blood coagulation; GO:0032383 regulation of intracellular cholesterol transport; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0080134 regulation of response to stress; GO:1990778 protein localization to cell periphery; GO:0051239 regulation of multicellular organismal process; GO:0060341 regulation of cellular localization; GO:0051259 protein oligomerization; GO:1900047 negative regulation of hemostasis; GO:0009653 anatomical structure morphogenesis; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0043062 extracellular structure organization; GO:1902580 single-organism cellular localization; GO:0042176 regulation of protein catabolic process; GO:0007275 multicellular organism development; GO:0031579 membrane raft organization; GO:0034613 cellular protein localization; GO:0090150 establishment of protein localization to membrane; GO:0009966 regulation of signal transduction; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0006461 protein complex assembly; GO:0032382 positive regulation of intracellular sterol transport; GO:1905581 positive regulation of low-density lipoprotein particle clearance; GO:2000645 negative regulation of receptor catabolic process; GO:0030100 regulation of endocytosis; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0071709 membrane assembly; GO:0002376 immune system process; GO:0071702 organic substance transport; GO:0032101 regulation of response to external stimulus; GO:0072358 cardiovascular system development; GO:0098751 bone cell development; GO:0010033 response to organic substance; GO:0001765 membrane raft assembly; GO:1905602 positive regulation of receptor-mediated endocytosis involved in cholesterol transport; GO:0002263 cell activation involved in immune response; GO:0044091 membrane biogenesis; GO:0009892 negative regulation of metabolic process; GO:0060348 bone development; GO:0045184 establishment of protein localization; GO:0031330 negative regulation of cellular catabolic process; GO:0030195 negative regulation of blood coagulation; GO:0045055 regulated exocytosis; GO:0072659 protein localization to plasma membrane; GO:0051247 positive regulation of protein metabolic process; GO:0061041 regulation of wound healing; GO:0006996 organelle organization; GO:0006900 membrane budding; GO:0061024 membrane organization; GO:0031325 positive regulation of cellular metabolic process; GO:0001775 cell activation; GO:0006955 immune response; GO:0051179 localization; GO:1903034 regulation of response to wounding; GO:0050819 negative regulation of coagulation; GO:0006887 exocytosis; GO:0008284 positive regulation of cell proliferation; GO:0010256 endomembrane system organization; GO:0001568 blood vessel development; GO:0048869 cellular developmental process; GO:0032092 positive regulation of protein binding; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0051241 negative regulation of multicellular organismal process; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0051130 positive regulation of cellular component organization; GO:0006612 protein targeting to membrane; GO:0051649 establishment of localization in cell; GO:0010646 regulation of cell communication; GO:0032376 positive regulation of cholesterol transport; GO:0051262 protein tetramerization; GO:0022607 cellular component assembly; GO:0009893 positive regulation of metabolic process; GO:0051290 protein heterotetramerization; GO:1900046 regulation of hemostasis; GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process; GO:0097066 response to thyroid hormone; GO:0030198 extracellular matrix organization; GO:0048514 blood vessel morphogenesis; GO:0033036 macromolecule localization; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:0045937 positive regulation of phosphate metabolic process; GO:0071822 protein complex subunit organization; GO:1905597 positive regulation of low-density lipoprotein particle receptor binding; GO:0002521 leukocyte differentiation; GO:0002446 neutrophil mediated immunity; GO:0051098 regulation of binding; GO:0098609 cell-cell adhesion; GO:0001944 vasculature development; GO:0048522 positive regulation of cellular process; GO:0032386 regulation of intracellular transport; GO:1903363 negative regulation of cellular protein catabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0032374 regulation of cholesterol transport; GO:1902582 single-organism intracellular transport; GO:1903035 negative regulation of response to wounding; GO:0051050 positive regulation of transport; GO:0001921 positive regulation of receptor recycling; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0042221 response to chemical; GO:0010638 positive regulation of organelle organization; GO:0032940 secretion by cell; GO:0032380 regulation of intracellular sterol transport; GO:1905599 positive regulation of low-density lipoprotein receptor activity; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0043299 leukocyte degranulation; GO:0019220 regulation of phosphate metabolic process; GO:0070271 protein complex biogenesis; GO:0048856 anatomical structure development; GO:0001501 skeletal system development; GO:0048260 positive regulation of receptor-mediated endocytosis; GO:0016043 cellular component organization; GO:0031340 positive regulation of vesicle fusion; GO:0042177 negative regulation of protein catabolic process; GO:0002252 immune effector process; GO:0032377 regulation of intracellular lipid transport; GO:0060255 regulation of macromolecule metabolic process; GO:0045807 positive regulation of endocytosis; GO:0032368 regulation of lipid transport; GO:1905595 regulation of low-density lipoprotein particle receptor binding; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0043393 regulation of protein binding; GO:0030154 cell differentiation; GO:0023056 positive regulation of signaling; GO:0006886 intracellular protein transport; GO:0010984 regulation of lipoprotein particle clearance; GO:0009895 negative regulation of catabolic process; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:1900120 regulation of receptor binding; GO:0001919 regulation of receptor recycling; GO:0007589 body fluid secretion; GO:0050878 regulation of body fluid levels; GO:0030099 myeloid cell differentiation; GO:0032388 positive regulation of intracellular transport; GO:0051049 regulation of transport; GO:0010986 positive regulation of lipoprotein particle clearance; GO:0001932 regulation of protein phosphorylation; GO:0016050 vesicle organization; GO:0031401 positive regulation of protein modification process; GO:0033043 regulation of organelle organization; GO:0044802 single-organism membrane organization; GO:0048585 negative regulation of response to stimulus; GO:2000644 regulation of receptor catabolic process; GO:0043312 neutrophil degranulation; GO:0001934 positive regulation of protein phosphorylation; GO:0048518 positive regulation of biological process; GO:0061045 negative regulation of wound healing; GO:0032803 regulation of low-density lipoprotein particle receptor catabolic process; GO:0048534 hematopoietic or lymphoid organ development; GO:0030097 hemopoiesis; GO:0051641 cellular localization; GO:0043933 macromolecular complex subunit organization; GO:0002366 leukocyte activation involved in immune response; GO:0050818 regulation of coagulation; GO:0042119 neutrophil activation; GO:0070727 cellular macromolecule localization; GO:0002573 myeloid leukocyte differentiation; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:1900122 positive regulation of receptor binding; GO:0032370 positive regulation of lipid transport; GO:0051248 negative regulation of protein metabolic process; GO:0051128 regulation of cellular component organization; GO:0032373 positive regulation of sterol transport; GO:0009725 response to hormone; GO:0036035 osteoclast development; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0019898 extrinsic component of membrane; GO:0031090 organelle membrane; GO:1990667 PCSK9-AnxA2 complex; GO:0099568 cytoplasmic region; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0005913 cell-cell adherens junction; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0043228 non-membrane-bounded organelle; GO:0005604 basement membrane; GO:0005775 vacuolar lumen; GO:0005765 lysosomal membrane; GO:0070062 extracellular exosome; GO:0035749 myelin sheath adaxonal region; GO:0098590 plasma membrane region; GO:0044352 pinosome; GO:0031902 late endosome membrane; GO:0043209 myelin sheath; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0031252 cell leading edge; GO:0010008 endosome membrane; GO:0042995 cell projection; GO:0005770 late endosome; GO:0019897 extrinsic component of plasma membrane; GO:0030496 midbody; GO:0070161 anchoring junction; GO:0044440 endosomal part; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0042582 azurophil granule; GO:0031012 extracellular matrix; GO:0043231 intracellular membrane-bounded organelle; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043234 protein complex; GO:0042383 sarcolemma; GO:0043230 extracellular organelle; GO:0016323 basolateral plasma membrane; GO:0034774 secretory granule lumen; GO:0043218 compact myelin; GO:0005615 extracellular space; GO:0005938 cell cortex; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005911 cell-cell junction; GO:0044420 extracellular matrix component; GO:0048770 pigment granule; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0044354 macropinosome; GO:0044425 membrane part; GO:0044464 cell part; GO:0043220 Schmidt-Lanterman incisure; GO:0098805 whole membrane; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0005768 endosome; GO:0030141 secretory granule; GO:0005811 lipid particle; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0042470 melanosome; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0060205 cytoplasmic vesicle lumen; GO:0005578 proteinaceous extracellular matrix; GO:0001726 ruffle; GO:0005774 vacuolar membrane; GO:0009986 cell surface; GO:0044444 cytoplasmic part; ","GO:0004859 phospholipase inhibitor activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0004857 enzyme inhibitor activity; GO:0048306 calcium-dependent protein binding; GO:0017137 Rab GTPase binding; GO:1902936 phosphatidylinositol bisphosphate binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0098641 cadherin binding involved in cell-cell adhesion; GO:0008092 cytoskeletal protein binding; GO:0017016 Ras GTPase binding; GO:0005546 phosphatidylinositol-4,5-bisphosphate binding; GO:0005488 binding; GO:0035091 phosphatidylinositol binding; GO:0045296 cadherin binding; GO:0008289 lipid binding; GO:0043169 cation binding; GO:0044548 S100 protein binding; GO:0043168 anion binding; GO:0051020 GTPase binding; GO:0031267 small GTPase binding; GO:0019834 phospholipase A2 inhibitor activity; GO:0003723 RNA binding; GO:0005544 calcium-dependent phospholipid binding; GO:1901981 phosphatidylinositol phosphate binding; GO:0055102 lipase inhibitor activity; GO:0043167 ion binding; GO:0098632 protein binding involved in cell-cell adhesion; GO:0002020 protease binding; GO:0050839 cell adhesion molecule binding; GO:0030234 enzyme regulator activity; GO:0098631 protein binding involved in cell adhesion; GO:0003676 nucleic acid binding; GO:0005543 phospholipid binding; GO:0046872 metal ion binding; GO:0005509 calcium ion binding; GO:0019899 enzyme binding; ","K17092"]
["P07357","Complement component C8 alpha chain OS=Homo sapiens OX=9606 GN=C8A","C8A",65.163,112.47,28.6,13,19,13,1.075,1.07,1.048,0.934,0.926,0.963,0.884,0.000979,"extracellular\r","GO:0030449 regulation of complement activation; GO:0016064 immunoglobulin mediated immune response; GO:0019835 cytolysis; GO:2000257 regulation of protein activation cascade; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0002920 regulation of humoral immune response; GO:0002673 regulation of acute inflammatory response; GO:0006959 humoral immune response; GO:0080134 regulation of response to stress; GO:0050896 response to stimulus; GO:0031347 regulation of defense response; GO:0045087 innate immune response; GO:0019724 B cell mediated immunity; GO:0071704 organic substance metabolic process; GO:0006956 complement activation; GO:0008152 metabolic process; GO:0002250 adaptive immune response; GO:0006958 complement activation, classical pathway; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0002449 lymphocyte mediated immunity; GO:0050778 positive regulation of immune response; GO:0009987 cellular process; GO:0002697 regulation of immune effector process; GO:0010468 regulation of gene expression; GO:0002253 activation of immune response; GO:0002443 leukocyte mediated immunity; GO:0006950 response to stress; GO:0080090 regulation of primary metabolic process; GO:0072376 protein activation cascade; GO:0032101 regulation of response to external stimulus; GO:0002376 immune system process; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0050776 regulation of immune response; GO:0050789 regulation of biological process; GO:0006957 complement activation, alternative pathway; GO:0051246 regulation of protein metabolic process; GO:0002684 positive regulation of immune system process; GO:0048583 regulation of response to stimulus; GO:0070613 regulation of protein processing; GO:0050727 regulation of inflammatory response; GO:0019222 regulation of metabolic process; GO:0002682 regulation of immune system process; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:1903317 regulation of protein maturation; GO:0006952 defense response; GO:0048584 positive regulation of response to stimulus; GO:0006955 immune response; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0031226 intrinsic component of plasma membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0098796 membrane protein complex; GO:0071944 cell periphery; GO:0046930 pore complex; GO:0098797 plasma membrane protein complex; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0072562 blood microparticle; GO:0044459 plasma membrane part; GO:0044425 membrane part; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0005579 membrane attack complex; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0001848 complement binding; GO:0005515 protein binding; GO:0005488 binding; GO:0032403 protein complex binding; GO:0044877 macromolecular complex binding; ","K03997","C8A; complement component 8 subunit alpha","hsa05322 Systemic lupus erythematosus - Homo sapiens (human); hsa04610 Complement and coagulation cascades - Homo sapiens (human); hsa05146 Amoebiasis - Homo sapiens (human); hsa05020 Prion diseases - Homo sapiens (human); ","IPR020864; IPR009030; ","Membrane attack complex component/perforin (MACPF) domain; Growth factor receptor cysteine-rich domain; \r"]
["P07358","Complement component C8 beta chain OS=Homo sapiens OX=9606 GN=C8B","C8B",67.046,65.659,24.9,13,18,13,1.038,1.07,1.064,0.952,0.969,0.924,0.897,0.00286,"extracellular\r","GO:0030449 regulation of complement activation; GO:0016064 immunoglobulin mediated immune response; GO:0019835 cytolysis; GO:2000257 regulation of protein activation cascade; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0002920 regulation of humoral immune response; GO:0002673 regulation of acute inflammatory response; GO:0006959 humoral immune response; GO:0080134 regulation of response to stress; GO:0050896 response to stimulus; GO:0031347 regulation of defense response; GO:0045087 innate immune response; GO:0019724 B cell mediated immunity; GO:0071704 organic substance metabolic process; GO:0006956 complement activation; GO:0008152 metabolic process; GO:0002250 adaptive immune response; GO:0006958 complement activation, classical pathway; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0002449 lymphocyte mediated immunity; GO:0050778 positive regulation of immune response; GO:0009987 cellular process; GO:0002697 regulation of immune effector process; GO:0010468 regulation of gene expression; GO:0002253 activation of immune response; GO:0002443 leukocyte mediated immunity; GO:0006950 response to stress; GO:0080090 regulation of primary metabolic process; GO:0072376 protein activation cascade; GO:0032101 regulation of response to external stimulus; GO:0002376 immune system process; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0050776 regulation of immune response; GO:0050789 regulation of biological process; GO:0006957 complement activation, alternative pathway; GO:0051246 regulation of protein metabolic process; GO:0002684 positive regulation of immune system process; GO:0048583 regulation of response to stimulus; GO:0070613 regulation of protein processing; GO:0050727 regulation of inflammatory response; GO:0019222 regulation of metabolic process; GO:0002682 regulation of immune system process; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:1903317 regulation of protein maturation; GO:0006952 defense response; GO:0048584 positive regulation of response to stimulus; GO:0006955 immune response; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0031226 intrinsic component of plasma membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0098796 membrane protein complex; GO:0071944 cell periphery; GO:0046930 pore complex; GO:0098797 plasma membrane protein complex; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0044459 plasma membrane part; GO:0044464 cell part; GO:0044425 membrane part; GO:1903561 extracellular vesicle; GO:0005579 membrane attack complex; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0005515 protein binding; GO:0005488 binding; GO:0032403 protein complex binding; GO:0044877 macromolecular complex binding; ","K03998","C8B; complement component 8 subunit beta","hsa05322 Systemic lupus erythematosus - Homo sapiens (human); hsa04610 Complement and coagulation cascades - Homo sapiens (human); hsa05146 Amoebiasis - Homo sapiens (human); hsa05020 Prion diseases - Homo sapiens (human); ","IPR020864; ","Membrane attack complex component/perforin (MACPF) domain; \r"]
["P07360","Complement component C8 gamma chain OS=Homo sapiens OX=9606 GN=C8G","C8G",22.277,46.54,36.6,6,8,6,1.008,1.08,0.98,0.991,0.978,0.994,0.966,0.31,"extracellular\r","GO:0030449 regulation of complement activation; GO:0016064 immunoglobulin mediated immune response; GO:0019835 cytolysis; GO:2000257 regulation of protein activation cascade; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0002920 regulation of humoral immune response; GO:0002673 regulation of acute inflammatory response; GO:0006959 humoral immune response; GO:0080134 regulation of response to stress; GO:0050896 response to stimulus; GO:0031347 regulation of defense response; GO:0045087 innate immune response; GO:0019724 B cell mediated immunity; GO:0071704 organic substance metabolic process; GO:0006956 complement activation; GO:0008152 metabolic process; GO:0002250 adaptive immune response; GO:0006958 complement activation, classical pathway; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0002449 lymphocyte mediated immunity; GO:0050778 positive regulation of immune response; GO:0009987 cellular process; GO:0002697 regulation of immune effector process; GO:0010468 regulation of gene expression; GO:0002253 activation of immune response; GO:0002443 leukocyte mediated immunity; GO:0006950 response to stress; GO:0080090 regulation of primary metabolic process; GO:0032101 regulation of response to external stimulus; GO:0072376 protein activation cascade; GO:0002376 immune system process; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0050776 regulation of immune response; GO:0050789 regulation of biological process; GO:0006957 complement activation, alternative pathway; GO:0051246 regulation of protein metabolic process; GO:0002684 positive regulation of immune system process; GO:0048583 regulation of response to stimulus; GO:0070613 regulation of protein processing; GO:0050727 regulation of inflammatory response; GO:0019222 regulation of metabolic process; GO:0002682 regulation of immune system process; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0006952 defense response; GO:1903317 regulation of protein maturation; GO:0006955 immune response; GO:0048584 positive regulation of response to stimulus; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0031226 intrinsic component of plasma membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0098796 membrane protein complex; GO:0071944 cell periphery; GO:0046930 pore complex; GO:0098797 plasma membrane protein complex; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0072562 blood microparticle; GO:0044459 plasma membrane part; GO:0044464 cell part; GO:0044425 membrane part; GO:1903561 extracellular vesicle; GO:0005579 membrane attack complex; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0019842 vitamin binding; GO:0005488 binding; GO:0043178 alcohol binding; GO:0044877 macromolecular complex binding; GO:0019841 retinol binding; GO:0005501 retinoid binding; GO:0001848 complement binding; GO:0008289 lipid binding; GO:0005515 protein binding; GO:0019840 isoprenoid binding; GO:0032403 protein complex binding; GO:0036094 small molecule binding; ","K03999","C8G; complement component 8 subunit gamma","hsa05322 Systemic lupus erythematosus - Homo sapiens (human); hsa04610 Complement and coagulation cascades - Homo sapiens (human); hsa05146 Amoebiasis - Homo sapiens (human); hsa05020 Prion diseases - Homo sapiens (human); ","IPR012674; IPR000566; IPR011038; ","Calycin; Lipocalin/cytosolic fatty-acid binding domain; Calycin-like; \r"]
["P07384","Calpain-1 catalytic subunit OS=Homo sapiens OX=9606 GN=CAPN1","CAPN1",81.889,160.81,36.4,25,43,25,1.013,1.013,0.966,1.009,0.988,0.991,0.999,0.951,"nucleus\r","GO:0048732 gland development; GO:0045321 leukocyte activation; GO:0031424 keratinization; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:0009913 epidermal cell differentiation; GO:0008152 metabolic process; GO:0022617 extracellular matrix disassembly; GO:0008544 epidermis development; GO:0019538 protein metabolic process; GO:0030198 extracellular matrix organization; GO:0043170 macromolecule metabolic process; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0002443 leukocyte mediated immunity; GO:0043588 skin development; GO:0009888 tissue development; GO:0030216 keratinocyte differentiation; GO:0043112 receptor metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0002446 neutrophil mediated immunity; GO:0070268 cornification; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0031323 regulation of cellular metabolic process; GO:0010506 regulation of autophagy; GO:0032501 multicellular organismal process; GO:0002444 myeloid leukocyte mediated immunity; GO:0016241 regulation of macroautophagy; GO:0060056 mammary gland involution; GO:0006810 transport; GO:0032801 receptor catabolic process; GO:1901575 organic substance catabolic process; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0050790 regulation of catalytic activity; GO:0032940 secretion by cell; GO:0044260 cellular macromolecule metabolic process; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0009887 animal organ morphogenesis; GO:0043299 leukocyte degranulation; GO:0048856 anatomical structure development; GO:0030855 epithelial cell differentiation; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0002283 neutrophil activation involved in immune response; GO:0042127 regulation of cell proliferation; GO:0002252 immune effector process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0030879 mammary gland development; GO:0009653 anatomical structure morphogenesis; GO:0030154 cell differentiation; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0043062 extracellular structure organization; GO:0044248 cellular catabolic process; GO:0006508 proteolysis; GO:0007275 multicellular organism development; GO:0036230 granulocyte activation; GO:0060443 mammary gland morphogenesis; GO:0009987 cellular process; GO:0048771 tissue remodeling; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0002263 cell activation involved in immune response; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0009057 macromolecule catabolic process; GO:0022411 cellular component disassembly; GO:0001775 cell activation; GO:0012501 programmed cell death; GO:0006955 immune response; GO:0051179 localization; GO:0097264 self proteolysis; GO:0009056 catabolic process; GO:0008284 positive regulation of cell proliferation; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:0006887 exocytosis; GO:0022612 gland morphogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0101002 ficolin-1-rich granule; GO:0005925 focal adhesion; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030055 cell-substrate junction; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005773 vacuole; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0004175 endopeptidase activity; GO:0004198 calcium-dependent cysteine-type endopeptidase activity; GO:0008233 peptidase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0008234 cysteine-type peptidase activity; GO:0005509 calcium ion binding; GO:0004197 cysteine-type endopeptidase activity; ","K01367","CAPN1; calpain-1 [EC:3.4.22.52]","hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04218 Cellular senescence - Homo sapiens (human); hsa04210 Apoptosis - Homo sapiens (human); hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); hsa04217 Necroptosis - Homo sapiens (human); ","IPR022683; IPR022682; IPR033883; IPR002048; IPR011992; IPR001300; ","\"Peptidase C2, calpain, domain III; Peptidase C2, calpain, large subunit, domain III; Calpain subdomain III; EF-hand domain; EF-hand domain pair; Peptidase C2, calpain, catalytic domain; \"\r"]
["P07437","Tubulin beta chain OS=Homo sapiens OX=9606 GN=TUBB","TUBB",49.67,92.827,61.3,19,107,4,1.074,1.004,1.067,0.97,0.953,0.944,0.912,0.0158,"cyto_nucl\r","GO:0044085 cellular component biogenesis; GO:0045321 leukocyte activation; GO:0060271 cilium assembly; GO:0044699 single-organism process; GO:0044782 cilium organization; GO:0051234 establishment of localization; GO:0051225 spindle assembly; GO:0051649 establishment of localization in cell; GO:0022607 cellular component assembly; GO:0044770 cell cycle phase transition; GO:0001906 cell killing; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0002228 natural killer cell mediated immunity; GO:0000278 mitotic cell cycle; GO:0002443 leukocyte mediated immunity; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0002444 myeloid leukocyte mediated immunity; GO:0006810 transport; GO:0000226 microtubule cytoskeleton organization; GO:1902589 single-organism organelle organization; GO:0001909 leukocyte mediated cytotoxicity; GO:0030030 cell projection organization; GO:0032940 secretion by cell; GO:0051301 cell division; GO:0043299 leukocyte degranulation; GO:0006952 defense response; GO:0000086 G2/M transition of mitotic cell cycle; GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0007051 spindle organization; GO:0097711 ciliary basal body docking; GO:0050896 response to stimulus; GO:1903047 mitotic cell cycle process; GO:0022406 membrane docking; GO:0030705 cytoskeleton-dependent intracellular transport; GO:0045087 innate immune response; GO:0042267 natural killer cell mediated cytotoxicity; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0070925 organelle assembly; GO:0036230 granulocyte activation; GO:0002449 lymphocyte mediated immunity; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0044772 mitotic cell cycle phase transition; GO:0006950 response to stress; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0043312 neutrophil degranulation; GO:0007017 microtubule-based process; GO:0002263 cell activation involved in immune response; GO:0030031 cell projection assembly; GO:0051641 cellular localization; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0006996 organelle organization; GO:0006928 movement of cell or subcellular component; GO:0001775 cell activation; GO:0044839 cell cycle G2/M phase transition; GO:0022402 cell cycle process; GO:0006955 immune response; GO:0051179 localization; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0006887 exocytosis; ","GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:0099080 supramolecular complex; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0099513 polymeric cytoskeletal fiber; GO:0044430 cytoskeletal part; GO:0031967 organelle envelope; GO:0005576 extracellular region; GO:0099081 supramolecular polymer; GO:0042582 azurophil granule; GO:0031012 extracellular matrix; GO:0043231 intracellular membrane-bounded organelle; GO:0005766 primary lysosome; GO:0031975 envelope; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:1990904 ribonucleoprotein complex; GO:0043234 protein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043230 extracellular organelle; GO:0034774 secretory granule lumen; GO:0005874 microtubule; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0099512 supramolecular fiber; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0005641 nuclear envelope lumen; GO:0005856 cytoskeleton; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0031970 organelle envelope lumen; GO:0015630 microtubule cytoskeleton; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005635 nuclear envelope; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0043226 organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0035770 ribonucleoprotein granule; GO:0044297 cell body; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0031625 ubiquitin protein ligase binding; GO:0005102 receptor binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0042288 MHC class I protein binding; GO:0032794 GTPase activating protein binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0003924 GTPase activity; GO:0042287 MHC protein binding; GO:0043168 anion binding; GO:0019001 guanyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0005200 structural constituent of cytoskeleton; GO:0019904 protein domain specific binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0032561 guanyl ribonucleotide binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0005198 structural molecule activity; GO:0019899 enzyme binding; GO:0032403 protein complex binding; GO:0036094 small molecule binding; ","K07375","TUBB; tubulin beta","hsa04540 Gap junction - Homo sapiens (human); hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); ","IPR003008; IPR023123; IPR008280; IPR018316; ","\"Tubulin/FtsZ, GTPase domain; Tubulin, C-terminal; Tubulin/FtsZ, C-terminal; Tubulin/FtsZ, 2-layer sandwich domain; \"\r"]
["P07451","Carbonic anhydrase 3 OS=Homo sapiens OX=9606 GN=CA3","CA3",29.557,10.427,16.2,3,3,3,0.871,0.945,0.871,1.108,1.135,1.067,1.232,0.00304,"cytoplasm\r","GO:0006950 response to stress; GO:0045471 response to ethanol; GO:0044281 small molecule metabolic process; GO:1901700 response to oxygen-containing compound; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0071702 organic substance transport; GO:0097305 response to alcohol; GO:0010033 response to organic substance; GO:0050896 response to stimulus; GO:0016311 dephosphorylation; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0006810 transport; GO:0006820 anion transport; GO:0015711 organic anion transport; GO:0008152 metabolic process; GO:0042221 response to chemical; GO:0006730 one-carbon metabolic process; GO:0006793 phosphorus metabolic process; GO:0006811 ion transport; GO:0044710 single-organism metabolic process; GO:0015701 bicarbonate transport; GO:0006979 response to oxidative stress; GO:0051179 localization; GO:0009987 cellular process; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0044444 cytoplasmic part; ","GO:0016791 phosphatase activity; GO:0043167 ion binding; GO:0016829 lyase activity; GO:0016836 hydro-lyase activity; GO:0016787 hydrolase activity; GO:0008270 zinc ion binding; GO:0004089 carbonate dehydratase activity; GO:0016151 nickel cation binding; GO:0016835 carbon-oxygen lyase activity; GO:0046914 transition metal ion binding; GO:0042578 phosphoric ester hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0046872 metal ion binding; GO:0043169 cation binding; ","K01672","CA; carbonic anhydrase [EC:4.2.1.1]","hsa00910 Nitrogen metabolism - Homo sapiens (human); ","IPR001148; ","Alpha carbonic anhydrase; \r"]
["P07476","Involucrin OS=Homo sapiens OX=9606 GN=IVL","IVL",68.478,236.74,55.7,26,53,26,0.591,0.562,0.545,1.401,1.42,1.412,2.493,1.41e-06,"cytoplasm\r","GO:0044707 single-multicellular organism process; GO:0031424 keratinization; GO:0009628 response to abiotic stimulus; GO:0048869 cellular developmental process; GO:0018149 peptide cross-linking; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0018205 peptidyl-lysine modification; GO:0009913 epidermal cell differentiation; GO:0008152 metabolic process; GO:0030154 cell differentiation; GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine; GO:0008544 epidermis development; GO:0009314 response to radiation; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0043588 skin development; GO:0018199 peptidyl-glutamine modification; GO:0009888 tissue development; GO:0030216 keratinocyte differentiation; GO:0009416 response to light stimulus; GO:0048731 system development; GO:0070268 cornification; GO:0044763 single-organism cellular process; GO:0044238 primary metabolic process; GO:0032501 multicellular organismal process; GO:0018193 peptidyl-amino acid modification; GO:0048513 animal organ development; GO:0009411 response to UV; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0010224 response to UV-B; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0018262 isopeptide cross-linking; GO:0012501 programmed cell death; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:0048856 anatomical structure development; GO:0030855 epithelial cell differentiation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0005815 microtubule organizing center; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0001533 cornified envelope; GO:0005813 centrosome; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0060090 binding, bridging; GO:0030674 protein binding, bridging; GO:0005198 structural molecule activity; GO:0005488 binding; ",{"$nulls":3},"IPR019571; ","\"Involucrin, N-terminal; \"\r"]
["P07585","Decorin OS=Homo sapiens OX=9606 GN=DCN","DCN",39.746,292.25,45.1,17,121,16,1.217,1.199,1.198,0.804,0.821,0.802,0.672,7.85E-7,"extracellular\r","GO:0044700 single organism signaling; GO:0022414 reproductive process; GO:0009891 positive regulation of biosynthetic process; GO:0010821 regulation of mitochondrion organization; GO:0044237 cellular metabolic process; GO:0010594 regulation of endothelial cell migration; GO:1904181 positive regulation of membrane depolarization; GO:0009607 response to biotic stimulus; GO:0030203 glycosaminoglycan metabolic process; GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0090140 regulation of mitochondrial fission; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0060537 muscle tissue development; GO:0044763 single-organism cellular process; GO:0030205 dermatan sulfate metabolic process; GO:0090287 regulation of cellular response to growth factor stimulus; GO:0043086 negative regulation of catalytic activity; GO:0010506 regulation of autophagy; GO:1901343 negative regulation of vasculature development; GO:1902548 negative regulation of cellular response to vascular endothelial growth factor stimulus; GO:0051704 multi-organism process; GO:0016241 regulation of macroautophagy; GO:1901575 organic substance catabolic process; GO:1902532 negative regulation of intracellular signal transduction; GO:0006029 proteoglycan metabolic process; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0016239 positive regulation of macroautophagy; GO:0043436 oxoacid metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0000003 reproduction; GO:0044707 single-multicellular organism process; GO:0051901 positive regulation of mitochondrial depolarization; GO:1901700 response to oxygen-containing compound; GO:0018149 peptide cross-linking; GO:0048519 negative regulation of biological process; GO:0003254 regulation of membrane depolarization; GO:0009653 anatomical structure morphogenesis; GO:0023057 negative regulation of signaling; GO:0030208 dermatan sulfate biosynthetic process; GO:0046426 negative regulation of JAK-STAT cascade; GO:0010648 negative regulation of cell communication; GO:2000145 regulation of cell motility; GO:0009889 regulation of biosynthetic process; GO:0043062 extracellular structure organization; GO:0009896 positive regulation of catabolic process; GO:0061061 muscle structure development; GO:0044248 cellular catabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0061458 reproductive system development; GO:0001822 kidney development; GO:0006023 aminoglycan biosynthetic process; GO:0006950 response to stress; GO:0044711 single-organism biosynthetic process; GO:0051270 regulation of cellular component movement; GO:0032496 response to lipopolysaccharide; GO:0010033 response to organic substance; GO:1901576 organic substance biosynthetic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:1902547 regulation of cellular response to vascular endothelial growth factor stimulus; GO:0030336 negative regulation of cell migration; GO:0031325 positive regulation of cellular metabolic process; GO:0044283 small molecule biosynthetic process; GO:0043412 macromolecule modification; GO:0072330 monocarboxylic acid biosynthetic process; GO:0045936 negative regulation of phosphate metabolic process; GO:0051093 negative regulation of developmental process; GO:0030206 chondroitin sulfate biosynthetic process; GO:0009968 negative regulation of signal transduction; GO:0016053 organic acid biosynthetic process; GO:0010633 negative regulation of epithelial cell migration; GO:0006024 glycosaminoglycan biosynthetic process; GO:0018209 peptidyl-serine modification; GO:0031331 positive regulation of cellular catabolic process; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0031400 negative regulation of protein modification process; GO:0009611 response to wounding; GO:0040013 negative regulation of locomotion; GO:0030166 proteoglycan biosynthetic process; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0030198 extracellular matrix organization; GO:0034097 response to cytokine; GO:0031326 regulation of cellular biosynthetic process; GO:0002237 response to molecule of bacterial origin; GO:0048608 reproductive structure development; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0046394 carboxylic acid biosynthetic process; GO:0016525 negative regulation of angiogenesis; GO:0010638 positive regulation of organelle organization; GO:0007517 muscle organ development; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0036211 protein modification process; GO:0043549 regulation of kinase activity; GO:0014706 striated muscle tissue development; GO:0046425 regulation of JAK-STAT cascade; GO:0016043 cellular component organization; GO:2000021 regulation of ion homeostasis; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:1901566 organonitrogen compound biosynthetic process; GO:0051707 response to other organism; GO:0071704 organic substance metabolic process; GO:0033993 response to lipid; GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan; GO:0009612 response to mechanical stimulus; GO:0023056 positive regulation of signaling; GO:0090288 negative regulation of cellular response to growth factor stimulus; GO:0010647 positive regulation of cell communication; GO:0009059 macromolecule biosynthetic process; GO:0050655 dermatan sulfate proteoglycan metabolic process; GO:0019221 cytokine-mediated signaling pathway; GO:0006355 regulation of transcription, DNA-templated; GO:1903510 mucopolysaccharide metabolic process; GO:0001932 regulation of protein phosphorylation; GO:1901342 regulation of vasculature development; GO:0033043 regulation of organelle organization; GO:0044249 cellular biosynthetic process; GO:0010822 positive regulation of mitochondrion organization; GO:0018193 peptidyl-amino acid modification; GO:1901565 organonitrogen compound catabolic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0010563 negative regulation of phosphorus metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0009056 catabolic process; GO:0051881 regulation of mitochondrial membrane potential; GO:0071840 cellular component organization or biogenesis; GO:0065008 regulation of biological quality; GO:0007166 cell surface receptor signaling pathway; GO:0071345 cellular response to cytokine stimulus; GO:0044272 sulfur compound biosynthetic process; GO:0051900 regulation of mitochondrial depolarization; GO:0009605 response to external stimulus; GO:0032879 regulation of localization; GO:0044702 single organism reproductive process; GO:0032787 monocarboxylic acid metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006790 sulfur compound metabolic process; GO:0003006 developmental process involved in reproduction; GO:0051174 regulation of phosphorus metabolic process; GO:0010632 regulation of epithelial cell migration; GO:0031329 regulation of cellular catabolic process; GO:0044281 small molecule metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0009894 regulation of catabolic process; GO:0009100 glycoprotein metabolic process; GO:0031323 regulation of cellular metabolic process; GO:2000146 negative regulation of cell motility; GO:0032501 multicellular organismal process; GO:0060538 skeletal muscle organ development; GO:0006027 glycosaminoglycan catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0044710 single-organism metabolic process; GO:0010508 positive regulation of autophagy; GO:0009887 animal organ morphogenesis; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0045765 regulation of angiogenesis; GO:0051094 positive regulation of developmental process; GO:0050794 regulation of cellular process; GO:0001890 placenta development; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0048523 negative regulation of cellular process; GO:0032844 regulation of homeostatic process; GO:0051239 regulation of multicellular organismal process; GO:0014066 regulation of phosphatidylinositol 3-kinase signaling; GO:0010628 positive regulation of gene expression; GO:0051338 regulation of transferase activity; GO:1901135 carbohydrate derivative metabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0001933 negative regulation of protein phosphorylation; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:0009617 response to bacterium; GO:1904892 regulation of STAT cascade; GO:0051254 positive regulation of RNA metabolic process; GO:1902531 regulation of intracellular signal transduction; GO:0048731 system development; GO:1901136 carbohydrate derivative catabolic process; GO:0030334 regulation of cell migration; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0010596 negative regulation of endothelial cell migration; GO:0050650 chondroitin sulfate proteoglycan biosynthetic process; GO:0048584 positive regulation of response to stimulus; GO:0031328 positive regulation of cellular biosynthetic process; GO:0050793 regulation of developmental process; GO:1901564 organonitrogen compound metabolic process; GO:0006026 aminoglycan catabolic process; GO:1902533 positive regulation of intracellular signal transduction; GO:0051241 negative regulation of multicellular organismal process; GO:0030207 chondroitin sulfate catabolic process; GO:0030204 chondroitin sulfate metabolic process; GO:0051130 positive regulation of cellular component organization; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0033673 negative regulation of kinase activity; GO:0022617 extracellular matrix disassembly; GO:0007519 skeletal muscle tissue development; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:2000181 negative regulation of blood vessel morphogenesis; GO:0010468 regulation of gene expression; GO:0009101 glycoprotein biosynthetic process; GO:0009888 tissue development; GO:0048522 positive regulation of cellular process; GO:0051348 negative regulation of transferase activity; GO:1900746 regulation of vascular endothelial growth factor signaling pathway; GO:0042391 regulation of membrane potential; GO:0090141 positive regulation of mitochondrial fission; GO:0001655 urogenital system development; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0007568 aging; GO:0006469 negative regulation of protein kinase activity; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0044273 sulfur compound catabolic process; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:0051271 negative regulation of cellular component movement; GO:2000026 regulation of multicellular organismal development; GO:0045859 regulation of protein kinase activity; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0072001 renal system development; GO:0043207 response to external biotic stimulus; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0050651 dermatan sulfate proteoglycan biosynthetic process; GO:1904893 negative regulation of STAT cascade; GO:0050654 chondroitin sulfate proteoglycan metabolic process; GO:0042326 negative regulation of phosphorylation; GO:0009987 cellular process; GO:0006022 aminoglycan metabolic process; GO:0044712 single-organism catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0042060 wound healing; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0009057 macromolecule catabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0022411 cellular component disassembly; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0009967 positive regulation of signal transduction; GO:0051128 regulation of cellular component organization; GO:0040012 regulation of locomotion; GO:0065007 biological regulation; ","GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0005581 collagen trimer; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0005764 lysosome; GO:0044431 Golgi apparatus part; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0005796 Golgi lumen; GO:0012505 endomembrane system; GO:0005589 collagen type VI trimer; GO:0005576 extracellular region; GO:0043202 lysosomal lumen; GO:0099081 supramolecular polymer; GO:0031012 extracellular matrix; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0098647 collagen beaded filament; GO:0044437 vacuolar part; GO:0005578 proteinaceous extracellular matrix; GO:0005773 vacuole; GO:0005794 Golgi apparatus; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0003723 RNA binding; GO:0047485 protein N-terminus binding; GO:0044877 macromolecular complex binding; GO:0005515 protein binding; GO:0004860 protein kinase inhibitor activity; GO:0019887 protein kinase regulator activity; GO:0019207 kinase regulator activity; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0050840 extracellular matrix binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0097367 carbohydrate derivative binding; GO:0030234 enzyme regulator activity; GO:0019210 kinase inhibitor activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005518 collagen binding; GO:0005539 glycosaminoglycan binding; GO:0032403 protein complex binding; ","K04660","DCN; decorin","hsa04350 TGF-beta signaling pathway - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); ","IPR000372; IPR032675; ","\"Leucine-rich repeat N-terminal domain; Leucine-rich repeat domain, L domain-like; \"\r"]
["P07602","Prosaposin OS=Homo sapiens OX=9606 GN=PSAP","PSAP",58.112,15.301,13,7,8,7,0.888,0.921,0.913,1.06,0.969,1.242,1.202,0.135,"plasma membrane\r","GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0032270 positive regulation of cellular protein metabolic process; GO:0045321 leukocyte activation; GO:0048732 gland development; GO:0022414 reproductive process; GO:0044255 cellular lipid metabolic process; GO:0019216 regulation of lipid metabolic process; GO:0044237 cellular metabolic process; GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; GO:0008152 metabolic process; GO:0044093 positive regulation of molecular function; GO:0044702 single organism reproductive process; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:1901032 negative regulation of response to reactive oxygen species; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0051174 regulation of phosphorus metabolic process; GO:0002443 leukocyte mediated immunity; GO:0003006 developmental process involved in reproduction; GO:0006869 lipid transport; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0031323 regulation of cellular metabolic process; GO:0010506 regulation of autophagy; GO:0060736 prostate gland growth; GO:0032501 multicellular organismal process; GO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway; GO:0006810 transport; GO:0048513 animal organ development; GO:0080135 regulation of cellular response to stress; GO:1903205 regulation of hydrogen peroxide-induced cell death; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:1903202 negative regulation of oxidative stress-induced cell death; GO:0010604 positive regulation of macromolecule metabolic process; GO:0060548 negative regulation of cell death; GO:0030855 epithelial cell differentiation; GO:0050794 regulation of cellular process; GO:0000003 reproduction; GO:0044707 single-multicellular organism process; GO:0002283 neutrophil activation involved in immune response; GO:0031399 regulation of protein modification process; GO:0030850 prostate gland development; GO:0060742 epithelial cell differentiation involved in prostate gland development; GO:0002576 platelet degranulation; GO:0080134 regulation of response to stress; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0035265 organ growth; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:1901135 carbohydrate derivative metabolic process; GO:0007275 multicellular organism development; GO:0061458 reproductive system development; GO:0009966 regulation of signal transduction; GO:1902531 regulation of intracellular signal transduction; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0010876 lipid localization; GO:0071702 organic substance transport; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0002263 cell activation involved in immune response; GO:1900408 negative regulation of cellular response to oxidative stress; GO:0007186 G-protein coupled receptor signaling pathway; GO:0045055 regulated exocytosis; GO:0051247 positive regulation of protein metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0001775 cell activation; GO:1902882 regulation of response to oxidative stress; GO:0048584 positive regulation of response to stimulus; GO:0048589 developmental growth; GO:0006955 immune response; GO:0051179 localization; GO:0040007 growth; GO:1901564 organonitrogen compound metabolic process; GO:0006887 exocytosis; GO:0006643 membrane lipid metabolic process; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0006665 sphingolipid metabolic process; GO:0033036 macromolecule localization; GO:0070887 cellular response to chemical stimulus; GO:0006629 lipid metabolic process; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0045937 positive regulation of phosphate metabolic process; GO:0009888 tissue development; GO:0002446 neutrophil mediated immunity; GO:0006664 glycolipid metabolic process; GO:0048608 reproductive structure development; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0002444 myeloid leukocyte mediated immunity; GO:0001655 urogenital system development; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:1902883 negative regulation of response to oxidative stress; GO:0032940 secretion by cell; GO:1903206 negative regulation of hydrogen peroxide-induced cell death; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0043299 leukocyte degranulation; GO:0019220 regulation of phosphate metabolic process; GO:0048856 anatomical structure development; GO:1903509 liposaccharide metabolic process; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0006687 glycosphingolipid metabolic process; GO:0071310 cellular response to organic substance; GO:1903201 regulation of oxidative stress-induced cell death; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0043408 regulation of MAPK cascade; GO:0023056 positive regulation of signaling; GO:0010647 positive regulation of cell communication; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0001932 regulation of protein phosphorylation; GO:0031401 positive regulation of protein modification process; GO:0006807 nitrogen compound metabolic process; GO:0048585 negative regulation of response to stimulus; GO:0001934 positive regulation of protein phosphorylation; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:1900407 regulation of cellular response to oxidative stress; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0009967 positive regulation of signal transduction; GO:0043410 positive regulation of MAPK cascade; GO:1901031 regulation of response to reactive oxygen species; GO:0065007 biological regulation; GO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0005765 lysosomal membrane; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0098805 whole membrane; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0035577 azurophil granule membrane; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0016021 integral component of membrane; GO:0043202 lysosomal lumen; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0042582 azurophil granule; GO:0098852 lytic vacuole membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0030667 secretory granule membrane; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0030234 enzyme regulator activity; GO:0005102 receptor binding; GO:0005488 binding; GO:0008289 lipid binding; GO:0005515 protein binding; GO:0001664 G-protein coupled receptor binding; GO:0098772 molecular function regulator; GO:0008047 enzyme activator activity; ","K12382","PSAP; saposin","hsa04142 Lysosome - Homo sapiens (human); ","IPR008139; IPR011001; IPR007856; IPR008138; IPR003119; ","\"Saposin B type domain; Saposin-like; Saposin-like type B, region 1; Saposin B type, region 2; Saposin A-type domain; \"\r"]
["P07686","Beta-hexosaminidase subunit beta OS=Homo sapiens OX=9606 GN=HEXB","HEXB",63.111,71.64,25.9,14,29,14,1.04,1.051,1.044,0.945,1.003,0.991,0.937,0.0245,"endoplasmic reticulum\r","GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0007272 ensheathment of neurons; GO:0022414 reproductive process; GO:0006672 ceramide metabolic process; GO:0009891 positive regulation of biosynthetic process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0050877 neurological system process; GO:0006689 ganglioside catabolic process; GO:0030203 glycosaminoglycan metabolic process; GO:0008610 lipid biosynthetic process; GO:0007610 behavior; GO:0008152 metabolic process; GO:0008360 regulation of cell shape; GO:0044706 multi-multicellular organism process; GO:0044702 single organism reproductive process; GO:0055065 metal ion homeostasis; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0007399 nervous system development; GO:0006790 sulfur compound metabolic process; GO:0002443 leukocyte mediated immunity; GO:0003006 developmental process involved in reproduction; GO:0080090 regulation of primary metabolic process; GO:0001573 ganglioside metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044281 small molecule metabolic process; GO:0019953 sexual reproduction; GO:0044763 single-organism cellular process; GO:0009100 glycoprotein metabolic process; GO:0008347 glial cell migration; GO:0046514 ceramide catabolic process; GO:0048870 cell motility; GO:0031323 regulation of cellular metabolic process; GO:0005975 carbohydrate metabolic process; GO:0032501 multicellular organismal process; GO:0006874 cellular calcium ion homeostasis; GO:0051704 multi-organism process; GO:0006027 glycosaminoglycan catabolic process; GO:0042552 myelination; GO:0006810 transport; GO:0090407 organophosphate biosynthetic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:1901575 organic substance catabolic process; GO:0042063 gliogenesis; GO:0006029 proteoglycan metabolic process; GO:0044710 single-organism metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0048609 multicellular organismal reproductive process; GO:0043436 oxoacid metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0000003 reproduction; GO:0044707 single-multicellular organism process; GO:0002283 neutrophil activation involved in immune response; GO:0044267 cellular protein metabolic process; GO:0009313 oligosaccharide catabolic process; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0051171 regulation of nitrogen compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0044248 cellular catabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0007275 multicellular organism development; GO:0050885 neuromuscular process controlling balance; GO:0048878 chemical homeostasis; GO:0016042 lipid catabolic process; GO:0051254 positive regulation of RNA metabolic process; GO:0007617 mating behavior; GO:0044711 single-organism biosynthetic process; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0019098 reproductive behavior; GO:1901136 carbohydrate derivative catabolic process; GO:0010876 lipid localization; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:0002263 cell activation involved in immune response; GO:1901576 organic substance biosynthetic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0045055 regulated exocytosis; GO:0006873 cellular ion homeostasis; GO:0007618 mating; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0019915 lipid storage; GO:0080171 lytic vacuole organization; GO:0001775 cell activation; GO:0006928 movement of cell or subcellular component; GO:0044242 cellular lipid catabolic process; GO:0019637 organophosphate metabolic process; GO:0007605 sensory perception of sound; GO:0006644 phospholipid metabolic process; GO:0006955 immune response; GO:0031328 positive regulation of cellular biosynthetic process; GO:0051179 localization; GO:0046479 glycosphingolipid catabolic process; GO:0050905 neuromuscular process; GO:0050793 regulation of developmental process; GO:0006887 exocytosis; GO:1901564 organonitrogen compound metabolic process; GO:0060179 male mating behavior; GO:0072503 cellular divalent inorganic cation homeostasis; GO:0051674 localization of cell; GO:0006643 membrane lipid metabolic process; GO:0019377 glycolipid catabolic process; GO:0006026 aminoglycan catabolic process; GO:0048869 cellular developmental process; GO:0008654 phospholipid biosynthetic process; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0009058 biosynthetic process; GO:0042340 keratan sulfate catabolic process; GO:0030207 chondroitin sulfate catabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0030204 chondroitin sulfate metabolic process; GO:0042339 keratan sulfate metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0006665 sphingolipid metabolic process; GO:0007033 vacuole organization; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0033036 macromolecule localization; GO:0002274 myeloid leukocyte activation; GO:0006629 lipid metabolic process; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0007600 sensory perception; GO:0046466 membrane lipid catabolic process; GO:0048477 oogenesis; GO:0050801 ion homeostasis; GO:0031326 regulation of cellular biosynthetic process; GO:0055074 calcium ion homeostasis; GO:0002446 neutrophil mediated immunity; GO:0098771 inorganic ion homeostasis; GO:0006664 glycolipid metabolic process; GO:0019725 cellular homeostasis; GO:0048522 positive regulation of cellular process; GO:0043603 cellular amide metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0007040 lysosome organization; GO:0016052 carbohydrate catabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0009566 fertilization; GO:0050789 regulation of biological process; GO:0032940 secretion by cell; GO:0022412 cellular process involved in reproduction in multicellular organism; GO:0019222 regulation of metabolic process; GO:0043299 leukocyte degranulation; GO:0044273 sulfur compound catabolic process; GO:0040011 locomotion; GO:0006082 organic acid metabolic process; GO:0072507 divalent inorganic cation homeostasis; GO:0048856 anatomical structure development; GO:0001501 skeletal system development; GO:0050954 sensory perception of mechanical stimulus; GO:0016043 cellular component organization; GO:0016477 cell migration; GO:1903509 liposaccharide metabolic process; GO:0002252 immune effector process; GO:0007292 female gamete generation; GO:0060255 regulation of macromolecule metabolic process; GO:0008366 axon ensheathment; GO:0030003 cellular cation homeostasis; GO:0006687 glycosphingolipid metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0007341 penetration of zona pellucida; GO:0050896 response to stimulus; GO:0055082 cellular chemical homeostasis; GO:0048468 cell development; GO:0071704 organic substance metabolic process; GO:0030149 sphingolipid catabolic process; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:0055080 cation homeostasis; GO:0050654 chondroitin sulfate proteoglycan metabolic process; GO:0043615 astrocyte cell migration; GO:0007281 germ cell development; GO:0034641 cellular nitrogen compound metabolic process; GO:0008049 male courtship behavior; GO:0051235 maintenance of location; GO:0036230 granulocyte activation; GO:0009311 oligosaccharide metabolic process; GO:0006022 aminoglycan metabolic process; GO:0009987 cellular process; GO:0030212 hyaluronan metabolic process; GO:0003008 system process; GO:0006355 regulation of transcription, DNA-templated; GO:1903510 mucopolysaccharide metabolic process; GO:0044724 single-organism carbohydrate catabolic process; GO:0030214 hyaluronan catabolic process; GO:0044712 single-organism catabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0043312 neutrophil degranulation; GO:0007338 single fertilization; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0007276 gamete generation; GO:0044249 cellular biosynthetic process; GO:0002366 leukocyte activation involved in immune response; GO:0032504 multicellular organism reproduction; GO:0007619 courtship behavior; GO:0042119 neutrophil activation; GO:1901565 organonitrogen compound catabolic process; GO:0044767 single-organism developmental process; GO:0009057 macromolecule catabolic process; GO:0044703 multi-organism reproductive process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0007626 locomotory behavior; GO:0006875 cellular metal ion homeostasis; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0051128 regulation of cellular component organization; GO:0009056 catabolic process; GO:0022604 regulation of cell morphogenesis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0043202 lysosomal lumen; GO:0005576 extracellular region; GO:0042582 azurophil granule; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0001669 acrosomal vesicle; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0097223 sperm part; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0008375 acetylglucosaminyltransferase activity; GO:0046982 protein heterodimerization activity; GO:0016758 transferase activity, transferring hexosyl groups; GO:0046983 protein dimerization activity; GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds; GO:0008194 UDP-glycosyltransferase activity; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0016798 hydrolase activity, acting on glycosyl bonds; GO:0004563 beta-N-acetylhexosaminidase activity; GO:0016757 transferase activity, transferring glycosyl groups; GO:0016740 transferase activity; GO:0015929 hexosaminidase activity; ","K12373","HEXA_B; hexosaminidase [EC:3.2.1.52]","hsa04142 Lysosome - Homo sapiens (human); hsa00511 Other glycan degradation - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00603 Glycosphingolipid biosynthesis - globo and isoglobo series - Homo sapiens (human); hsa00604 Glycosphingolipid biosynthesis - ganglio series - Homo sapiens (human); hsa00531 Glycosaminoglycan degradation - Homo sapiens (human); hsa00520 Amino sugar and nucleotide sugar metabolism - Homo sapiens (human); ","IPR029018; IPR015883; IPR029019; IPR017853; IPR013781; ","\"Chitobiase/beta-hexosaminidase domain 2-like; Glycoside hydrolase family 20, catalytic domain; Beta-hexosaminidase, eukaryotic type, N-terminal; Glycoside hydrolase superfamily; Glycoside hydrolase, catalytic domain; \"\r"]
["P07737","Profilin-1 OS=Homo sapiens OX=9606 GN=PFN1","PFN1",15.054,158,72.1,11,38,11,0.957,0.934,0.903,1.053,1.102,1.078,1.157,0.0024,"cytoplasm\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0030335 positive regulation of cell migration; GO:0007166 cell surface receptor signaling pathway; GO:0060491 regulation of cell projection assembly; GO:0035148 tube formation; GO:0043009 chordate embryonic development; GO:0009891 positive regulation of biosynthetic process; GO:0030832 regulation of actin filament length; GO:0030036 actin cytoskeleton organization; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:1900029 positive regulation of ruffle assembly; GO:0044093 positive regulation of molecular function; GO:0032535 regulation of cellular component size; GO:0070848 response to growth factor; GO:0051493 regulation of cytoskeleton organization; GO:0016055 Wnt signaling pathway; GO:0009790 embryo development; GO:0031333 negative regulation of protein complex assembly; GO:0048598 embryonic morphogenesis; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0010632 regulation of epithelial cell migration; GO:0051054 positive regulation of DNA metabolic process; GO:0080090 regulation of primary metabolic process; GO:0031346 positive regulation of cell projection organization; GO:0035239 tube morphogenesis; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044763 single-organism cellular process; GO:0051272 positive regulation of cellular component movement; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0051336 regulation of hydrolase activity; GO:0007267 cell-cell signaling; GO:0050434 positive regulation of viral transcription; GO:0050790 regulation of catalytic activity; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0060071 Wnt signaling pathway, planar cell polarity pathway; GO:0010604 positive regulation of macromolecule metabolic process; GO:0032781 positive regulation of ATPase activity; GO:0030837 negative regulation of actin filament polymerization; GO:1902905 positive regulation of supramolecular fiber organization; GO:0032233 positive regulation of actin filament bundle assembly; GO:1902903 regulation of supramolecular fiber organization; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0002009 morphogenesis of an epithelium; GO:0032956 regulation of actin cytoskeleton organization; GO:2000147 positive regulation of cell motility; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0051239 regulation of multicellular organismal process; GO:0009653 anatomical structure morphogenesis; GO:0060606 tube closure; GO:0051345 positive regulation of hydrolase activity; GO:2000145 regulation of cell motility; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0007275 multicellular organism development; GO:0016331 morphogenesis of embryonic epithelium; GO:0007010 cytoskeleton organization; GO:0001843 neural tube closure; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0060562 epithelial tube morphogenesis; GO:0051254 positive regulation of RNA metabolic process; GO:0051495 positive regulation of cytoskeleton organization; GO:0051270 regulation of cellular component movement; GO:0032231 regulation of actin filament bundle assembly; GO:0048731 system development; GO:0043900 regulation of multi-organism process; GO:0030334 regulation of cell migration; GO:0032970 regulation of actin filament-based process; GO:1900027 regulation of ruffle assembly; GO:0010033 response to organic substance; GO:0030838 positive regulation of actin filament polymerization; GO:0051492 regulation of stress fiber assembly; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0008064 regulation of actin polymerization or depolymerization; GO:0046782 regulation of viral transcription; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0031325 positive regulation of cellular metabolic process; GO:0051496 positive regulation of stress fiber assembly; GO:0031647 regulation of protein stability; GO:0031328 positive regulation of cellular biosynthetic process; GO:0050793 regulation of developmental process; GO:0050821 protein stabilization; GO:0001841 neural tube formation; GO:0030833 regulation of actin filament polymerization; GO:0032273 positive regulation of protein polymerization; GO:0040017 positive regulation of locomotion; GO:0051129 negative regulation of cellular component organization; GO:0044699 single-organism process; GO:0071363 cellular response to growth factor stimulus; GO:0035567 non-canonical Wnt signaling pathway; GO:0051130 positive regulation of cellular component organization; GO:1905330 regulation of morphogenesis of an epithelium; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0048729 tissue morphogenesis; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0032271 regulation of protein polymerization; GO:0031334 positive regulation of protein complex assembly; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:1903902 positive regulation of viral life cycle; GO:0010468 regulation of gene expression; GO:0035295 tube development; GO:0060429 epithelium development; GO:0043902 positive regulation of multi-organism process; GO:0009888 tissue development; GO:0031326 regulation of cellular biosynthetic process; GO:0051494 negative regulation of cytoskeleton organization; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0198738 cell-cell signaling by wnt; GO:1902589 single-organism organelle organization; GO:0010639 negative regulation of organelle organization; GO:0043254 regulation of protein complex assembly; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0051052 regulation of DNA metabolic process; GO:0043462 regulation of ATPase activity; GO:0010638 positive regulation of organelle organization; GO:1902904 negative regulation of supramolecular fiber organization; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0048856 anatomical structure development; GO:0032232 negative regulation of actin filament bundle assembly; GO:2000026 regulation of multicellular organismal development; GO:0090175 regulation of establishment of planar polarity; GO:0016043 cellular component organization; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0071310 cellular response to organic substance; GO:0031344 regulation of cell projection organization; GO:0044087 regulation of cellular component biogenesis; GO:0050896 response to stimulus; GO:0021915 neural tube development; GO:0072175 epithelial tube formation; GO:2000027 regulation of organ morphogenesis; GO:0009987 cellular process; GO:0006355 regulation of transcription, DNA-templated; GO:0009792 embryo development ending in birth or egg hatching; GO:0050792 regulation of viral process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0033043 regulation of organelle organization; GO:0051497 negative regulation of stress fiber assembly; GO:0010556 regulation of macromolecule biosynthetic process; GO:0010634 positive regulation of epithelial cell migration; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0001838 embryonic epithelial tube formation; GO:0014020 primary neural tube formation; GO:0048524 positive regulation of viral process; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0090066 regulation of anatomical structure size; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0051128 regulation of cellular component organization; GO:0032272 negative regulation of protein polymerization; GO:1903900 regulation of viral life cycle; GO:0040012 regulation of locomotion; GO:0044089 positive regulation of cellular component biogenesis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005938 cell cortex; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0099568 cytoplasmic region; GO:0044424 intracellular part; GO:0005623 cell; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0005924 cell-substrate adherens junction; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0070161 anchoring junction; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0045202 synapse; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0072562 blood microparticle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0005102 receptor binding; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:1902936 phosphatidylinositol bisphosphate binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0008092 cytoskeletal protein binding; GO:0017016 Ras GTPase binding; GO:0003785 actin monomer binding; GO:0005488 binding; GO:0005546 phosphatidylinositol-4,5-bisphosphate binding; GO:0045296 cadherin binding; GO:0035091 phosphatidylinositol binding; GO:0008289 lipid binding; GO:0043168 anion binding; GO:0030554 adenyl nucleotide binding; GO:0051020 GTPase binding; GO:0000774 adenyl-nucleotide exchange factor activity; GO:0017076 purine nucleotide binding; GO:0031267 small GTPase binding; GO:1901981 phosphatidylinositol phosphate binding; GO:0003723 RNA binding; GO:0017048 Rho GTPase binding; GO:0043167 ion binding; GO:0000166 nucleotide binding; GO:0070064 proline-rich region binding; GO:0050839 cell adhesion molecule binding; GO:0030234 enzyme regulator activity; GO:0005543 phospholipid binding; GO:0003676 nucleic acid binding; GO:0003779 actin binding; GO:0060590 ATPase regulator activity; GO:0019899 enzyme binding; GO:0036094 small molecule binding; ","K05759","PFN; profilin","hsa05132 Salmonella infection - Homo sapiens (human); hsa04015 Rap1 signaling pathway - Homo sapiens (human); hsa05131 Shigellosis - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); "]
["P07738","Bisphosphoglycerate mutase OS=Homo sapiens OX=9606 GN=BPGM","BPGM",30.005,27.998,22.8,5,9,5,0.881,0.876,0.859,1.098,1.081,1.092,1.25,1.75e-05,"cytoplasm\r","GO:0006757 ATP generation from ADP; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0006165 nucleoside diphosphate phosphorylation; GO:0046031 ADP metabolic process; GO:0019362 pyridine nucleotide metabolic process; GO:0019319 hexose biosynthetic process; GO:0006096 glycolytic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0009185 ribonucleoside diphosphate metabolic process; GO:0046939 nucleotide phosphorylation; GO:0009135 purine nucleoside diphosphate metabolic process; GO:0044237 cellular metabolic process; GO:0072524 pyridine-containing compound metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0006006 glucose metabolic process; GO:0051196 regulation of coenzyme metabolic process; GO:0008152 metabolic process; GO:0006094 gluconeogenesis; GO:0006091 generation of precursor metabolites and energy; GO:0006753 nucleoside phosphate metabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0051193 regulation of cofactor metabolic process; GO:0051174 regulation of phosphorus metabolic process; GO:0009179 purine ribonucleoside diphosphate metabolic process; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0080090 regulation of primary metabolic process; GO:0043456 regulation of pentose-phosphate shunt; GO:0010675 regulation of cellular carbohydrate metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0044281 small molecule metabolic process; GO:0043470 regulation of carbohydrate catabolic process; GO:0044763 single-organism cellular process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0072521 purine-containing compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0006732 coenzyme metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0005975 carbohydrate metabolic process; GO:0032501 multicellular organismal process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0016052 carbohydrate catabolic process; GO:0051186 cofactor metabolic process; GO:1902031 regulation of NADP metabolic process; GO:1901575 organic substance catabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0050789 regulation of biological process; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0006082 organic acid metabolic process; GO:0006140 regulation of nucleotide metabolic process; GO:0043436 oxoacid metabolic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0016310 phosphorylation; GO:0016051 carbohydrate biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0046496 nicotinamide nucleotide metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0009259 ribonucleotide metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0046364 monosaccharide biosynthetic process; GO:0071704 organic substance metabolic process; GO:0006090 pyruvate metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0005996 monosaccharide metabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0009987 cellular process; GO:0009119 ribonucleoside metabolic process; GO:0009132 nucleoside diphosphate metabolic process; GO:0043471 regulation of cellular carbohydrate catabolic process; GO:0046034 ATP metabolic process; GO:0044724 single-organism carbohydrate catabolic process; GO:0044711 single-organism biosynthetic process; GO:0044712 single-organism catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0006109 regulation of carbohydrate metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0006163 purine nucleotide metabolic process; GO:0034248 regulation of cellular amide metabolic process; GO:0007585 respiratory gaseous exchange; GO:0046128 purine ribonucleoside metabolic process; GO:0043455 regulation of secondary metabolic process; GO:0006793 phosphorus metabolic process; GO:0044283 small molecule biosynthetic process; GO:0019752 carboxylic acid metabolic process; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0009056 catabolic process; GO:0019318 hexose metabolic process; GO:0065007 biological regulation; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016853 isomerase activity; GO:0046538 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity; GO:0003824 catalytic activity; GO:0016868 intramolecular transferase activity, phosphotransferases; GO:0004619 phosphoglycerate mutase activity; GO:0016787 hydrolase activity; GO:0004082 bisphosphoglycerate mutase activity; GO:0016866 intramolecular transferase activity; ","K01837","BPGM; bisphosphoglycerate/phosphoglycerate mutase [EC:5.4.2.4 5.4.2.11]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00260 Glycine, serine and threonine metabolism - Homo sapiens (human); hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human); "]
["P07741","Adenine phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=APRT","APRT",19.608,11.658,25,5,10,5,0.922,1.023,0.936,1.071,1.077,1.031,1.103,0.0478,"cytoplasm\r","GO:0046083 adenine metabolic process; GO:0009116 nucleoside metabolic process; GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0048732 gland development; GO:0009163 nucleoside biosynthetic process; GO:0046129 purine ribonucleoside biosynthetic process; GO:0043174 nucleoside salvage; GO:0007625 grooming behavior; GO:0044237 cellular metabolic process; GO:0007610 behavior; GO:0046390 ribose phosphate biosynthetic process; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0046112 nucleobase biosynthetic process; GO:0009719 response to endogenous stimulus; GO:0019693 ribose phosphate metabolic process; GO:1901652 response to peptide; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0018130 heterocycle biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0072521 purine-containing compound metabolic process; GO:0032501 multicellular organismal process; GO:0009168 purine ribonucleoside monophosphate biosynthetic process; GO:0090407 organophosphate biosynthetic process; GO:0006810 transport; GO:0010243 response to organonitrogen compound; GO:0048513 animal organ development; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:1901698 response to nitrogen compound; GO:0032869 cellular response to insulin stimulus; GO:0009112 nucleobase metabolic process; GO:0009126 purine nucleoside monophosphate metabolic process; GO:0006164 purine nucleotide biosynthetic process; GO:0044708 single-organism behavior; GO:1901362 organic cyclic compound biosynthetic process; GO:0044707 single-multicellular organism process; GO:0002283 neutrophil activation involved in immune response; GO:0009259 ribonucleotide metabolic process; GO:1901700 response to oxygen-containing compound; GO:0046033 AMP metabolic process; GO:0030879 mammary gland development; GO:0044209 AMP salvage; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:1901135 carbohydrate derivative metabolic process; GO:0007275 multicellular organism development; GO:0009119 ribonucleoside metabolic process; GO:0044711 single-organism biosynthetic process; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0006144 purine nucleobase metabolic process; GO:0044238 primary metabolic process; GO:0042455 ribonucleoside biosynthetic process; GO:0002263 cell activation involved in immune response; GO:1901576 organic substance biosynthetic process; GO:0006163 purine nucleotide metabolic process; GO:0045055 regulated exocytosis; GO:0006793 phosphorus metabolic process; GO:0009260 ribonucleotide biosynthetic process; GO:0006167 AMP biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0001775 cell activation; GO:0006955 immune response; GO:0051179 localization; GO:0009123 nucleoside monophosphate metabolic process; GO:0006887 exocytosis; GO:1901564 organonitrogen compound metabolic process; GO:0046148 pigment biosynthetic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0046084 adenine biosynthetic process; GO:0009156 ribonucleoside monophosphate biosynthetic process; GO:0043096 purine nucleobase salvage; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:1901653 cellular response to peptide; GO:0006753 nucleoside phosphate metabolic process; GO:0070887 cellular response to chemical stimulus; GO:0002274 myeloid leukocyte activation; GO:0007595 lactation; GO:0032502 developmental process; GO:0009113 purine nucleobase biosynthetic process; GO:0002446 neutrophil mediated immunity; GO:1901360 organic cyclic compound metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0042451 purine nucleoside biosynthetic process; GO:0071417 cellular response to organonitrogen compound; GO:0042221 response to chemical; GO:0032868 response to insulin; GO:0043434 response to peptide hormone; GO:1901699 cellular response to nitrogen compound; GO:0032870 cellular response to hormone stimulus; GO:0043094 cellular metabolic compound salvage; GO:0072522 purine-containing compound biosynthetic process; GO:0032940 secretion by cell; GO:0006168 adenine salvage; GO:1901657 glycosyl compound metabolic process; GO:0043299 leukocyte degranulation; GO:0048856 anatomical structure development; GO:0043173 nucleotide salvage; GO:0009165 nucleotide biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0002252 immune effector process; GO:0071310 cellular response to organic substance; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0071375 cellular response to peptide hormone stimulus; GO:0034641 cellular nitrogen compound metabolic process; GO:0036230 granulocyte activation; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0007589 body fluid secretion; GO:0009124 nucleoside monophosphate biosynthetic process; GO:0050878 regulation of body fluid levels; GO:0006166 purine ribonucleoside salvage; GO:0042440 pigment metabolic process; GO:0009127 purine nucleoside monophosphate biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0032261 purine nucleotide salvage; GO:0043312 neutrophil degranulation; GO:0044249 cellular biosynthetic process; GO:0002366 leukocyte activation involved in immune response; GO:0046128 purine ribonucleoside metabolic process; GO:0042119 neutrophil activation; GO:1901701 cellular response to oxygen-containing compound; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0009152 purine ribonucleotide biosynthetic process; GO:0071495 cellular response to endogenous stimulus; GO:1901659 glycosyl compound biosynthetic process; GO:0044767 single-organism developmental process; GO:0009150 purine ribonucleotide metabolic process; GO:0009725 response to hormone; GO:0043101 purine-containing compound salvage; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0016763 transferase activity, transferring pentosyl groups; GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0000166 nucleotide binding; GO:0002055 adenine binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0002054 nucleobase binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016208 AMP binding; GO:0002060 purine nucleobase binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0003999 adenine phosphoribosyltransferase activity; GO:0043169 cation binding; GO:0016757 transferase activity, transferring glycosyl groups; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; ","K00759","APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]","hsa00230 Purine metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR000836; IPR029057; ","Phosphoribosyltransferase domain; Phosphoribosyltransferase-like; \r"]
["P07814","Bifunctional glutamate/proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS","EPRS",170.59,193.11,18.8,24,35,23,0.903,0.885,0.923,1.081,1.077,1.096,1.2,0.00016,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0006518 peptide metabolic process; GO:0010608 posttranscriptional regulation of gene expression; GO:0071346 cellular response to interferon-gamma; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0071345 cellular response to cytokine stimulus; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0006418 tRNA aminoacylation for protein translation; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0006412 translation; GO:0070887 cellular response to chemical stimulus; GO:0010468 regulation of gene expression; GO:0051716 cellular response to stimulus; GO:0071822 protein complex subunit organization; GO:0031326 regulation of cellular biosynthetic process; GO:0034097 response to cytokine; GO:0080090 regulation of primary metabolic process; GO:0043043 peptide biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0034249 negative regulation of cellular amide metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0016070 RNA metabolic process; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0042221 response to chemical; GO:0090304 nucleic acid metabolic process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0006952 defense response; GO:0070271 protein complex biogenesis; GO:0006082 organic acid metabolic process; GO:0043436 oxoacid metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0044267 cellular protein metabolic process; GO:0017148 negative regulation of translation; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0048523 negative regulation of cellular process; GO:0043039 tRNA aminoacylation; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:0045087 innate immune response; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0006433 prolyl-tRNA aminoacylation; GO:0006950 response to stress; GO:0010629 negative regulation of gene expression; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0034341 response to interferon-gamma; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0034248 regulation of cellular amide metabolic process; GO:0009890 negative regulation of biosynthetic process; GO:0006399 tRNA metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0006417 regulation of translation; GO:0051246 regulation of protein metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0043038 amino acid activation; GO:0051248 negative regulation of protein metabolic process; GO:0010467 gene expression; GO:0031327 negative regulation of cellular biosynthetic process; GO:0043604 amide biosynthetic process; GO:0006424 glutamyl-tRNA aminoacylation; GO:0006955 immune response; GO:0034660 ncRNA metabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043234 protein complex; GO:0005623 cell; GO:0005829 cytosol; GO:0097452 GAIT complex; GO:0044444 cytoplasmic part; GO:0017101 aminoacyl-tRNA synthetase multienzyme complex; ","GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds; GO:0003723 RNA binding; GO:0005524 ATP binding; GO:0035613 RNA stem-loop binding; GO:1901265 nucleoside phosphate binding; GO:0016875 ligase activity, forming carbon-oxygen bonds; GO:0004818 glutamate-tRNA ligase activity; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016874 ligase activity; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0004827 proline-tRNA ligase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0003676 nucleic acid binding; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0051020 GTPase binding; GO:0004812 aminoacyl-tRNA ligase activity; GO:0019899 enzyme binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K14163","EPRS; bifunctional glutamyl/prolyl-tRNA synthetase [EC:6.1.1.17 6.1.1.15]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00970 Aminoacyl-tRNA biosynthesis - Homo sapiens (human); hsa00860 Porphyrin and chlorophyll metabolism - Homo sapiens (human); ","IPR002314; IPR020056; IPR000738; IPR006195; IPR009068; IPR004154; IPR017449; IPR020059; IPR016061; IPR020061; IPR004046; IPR011035; IPR020058; IPR014729; IPR010987; IPR033721; ","\"Aminoacyl-tRNA synthetase, class II (G/ P/ S/T); Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain; WHEP-TRS domain; Aminoacyl-tRNA synthetase, class II; S15/NS1, RNA-binding; Anticodon-binding; Prolyl-tRNA synthetase, class II; Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain; Proline-tRNA ligase, class II, C-terminal; Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain; Glutathione S-transferase, C-terminal; Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain; Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain; Rossmann-like alpha/beta/alpha sandwich fold; Glutathione S-transferase, C-terminal-like; Prolyl-tRNA synthetase, catalytic domain; \"\r"]
["P07858","Cathepsin B OS=Homo sapiens OX=9606 GN=CTSB","CTSB",37.821,34.556,19.5,5,8,5,0.902,0.844,0.882,1.054,1.182,1.153,1.29,3.14E-3,"extracellular\r","GO:0044409 entry into host; GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0045321 leukocyte activation; GO:0022414 reproductive process; GO:0031347 regulation of defense response; GO:0044237 cellular metabolic process; GO:0046697 decidualization; GO:0008152 metabolic process; GO:0044702 single organism reproductive process; GO:0044706 multi-multicellular organism process; GO:0009719 response to endogenous stimulus; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0044259 multicellular organismal macromolecule metabolic process; GO:0030574 collagen catabolic process; GO:0046718 viral entry into host cell; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0051716 cellular response to stimulus; GO:0003006 developmental process involved in reproduction; GO:0002443 leukocyte mediated immunity; GO:0002758 innate immune response-activating signal transduction; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0048513 animal organ development; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0030163 protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0002682 regulation of immune system process; GO:0048609 multicellular organismal reproductive process; GO:0030855 epithelial cell differentiation; GO:0050794 regulation of cellular process; GO:0000003 reproduction; GO:0044707 single-multicellular organism process; GO:0060135 maternal process involved in female pregnancy; GO:0002283 neutrophil activation involved in immune response; GO:0001890 placenta development; GO:0051806 entry into cell of other organism involved in symbiotic interaction; GO:0043067 regulation of programmed cell death; GO:0044267 cellular protein metabolic process; GO:0080134 regulation of response to stress; GO:0007565 female pregnancy; GO:0031349 positive regulation of defense response; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0044248 cellular catabolic process; GO:0007275 multicellular organism development; GO:0061458 reproductive system development; GO:0050778 positive regulation of immune response; GO:0097067 cellular response to thyroid hormone stimulus; GO:0002253 activation of immune response; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0002263 cell activation involved in immune response; GO:0045055 regulated exocytosis; GO:0032963 collagen metabolic process; GO:0001775 cell activation; GO:0048584 positive regulation of response to stimulus; GO:0006955 immune response; GO:0051179 localization; GO:0006887 exocytosis; GO:0048869 cellular developmental process; GO:0044236 multicellular organism metabolic process; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0051234 establishment of localization; GO:0001893 maternal placenta development; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0045088 regulation of innate immune response; GO:0002221 pattern recognition receptor signaling pathway; GO:0097066 response to thyroid hormone; GO:0070887 cellular response to chemical stimulus; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0009888 tissue development; GO:0002446 neutrophil mediated immunity; GO:0048608 reproductive structure development; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0002444 myeloid leukocyte mediated immunity; GO:0030260 entry into host cell; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0032940 secretion by cell; GO:0002224 toll-like receptor signaling pathway; GO:0032870 cellular response to hormone stimulus; GO:0051828 entry into other organism involved in symbiotic interaction; GO:0065009 regulation of molecular function; GO:0043299 leukocyte degranulation; GO:0048856 anatomical structure development; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0002218 activation of innate immune response; GO:0002252 immune effector process; GO:0071310 cellular response to organic substance; GO:0019058 viral life cycle; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0044243 multicellular organismal catabolic process; GO:0016032 viral process; GO:0002757 immune response-activating signal transduction; GO:0006508 proteolysis; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0044265 cellular macromolecule catabolic process; GO:0045089 positive regulation of innate immune response; GO:0044712 single-organism catabolic process; GO:0043312 neutrophil degranulation; GO:0051701 interaction with host; GO:0048518 positive regulation of biological process; GO:0032504 multicellular organism reproduction; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0044767 single-organism developmental process; GO:0071495 cellular response to endogenous stimulus; GO:0009057 macromolecule catabolic process; GO:0044703 multi-organism reproductive process; GO:0002684 positive regulation of immune system process; GO:0009725 response to hormone; GO:0009056 catabolic process; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0036021 endolysosome lumen; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0036019 endolysosome; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0048770 pigment granule; GO:0043228 non-membrane-bounded organelle; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0005768 endosome; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0042470 melanosome; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0005730 nucleolus; GO:0005576 extracellular region; GO:0043202 lysosomal lumen; GO:0005739 mitochondrion; GO:0031904 endosome lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0008233 peptidase activity; GO:0044877 macromolecular complex binding; GO:0008236 serine-type peptidase activity; GO:0043394 proteoglycan binding; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0008234 cysteine-type peptidase activity; GO:0004175 endopeptidase activity; GO:0004252 serine-type endopeptidase activity; GO:0097367 carbohydrate derivative binding; GO:0003824 catalytic activity; GO:0017171 serine hydrolase activity; GO:0005488 binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0005518 collagen binding; GO:0004197 cysteine-type endopeptidase activity; GO:0001948 glycoprotein binding; GO:0032403 protein complex binding; ","K01363","CTSB; cathepsin B [EC:3.4.22.1]","hsa04142 Lysosome - Homo sapiens (human); hsa04924 Renin secretion - Homo sapiens (human); hsa04612 Antigen processing and presentation - Homo sapiens (human); hsa04210 Apoptosis - Homo sapiens (human); hsa04140 Autophagy - animal - Homo sapiens (human); hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human); ","IPR000668; IPR012599; ","\"Peptidase C1A, papain C-terminal; Peptidase C1A, propeptide; \"\r"]
["P07900","Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1","HSP90AA1",84.659,144.46,42.8,33,89,20,0.949,0.972,0.949,1.027,1.037,1.071,1.092,0.00416,"cytoplasm\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0022613 ribonucleoprotein complex biogenesis; GO:0045321 leukocyte activation; GO:0045428 regulation of nitric oxide biosynthetic process; GO:0022618 ribonucleoprotein complex assembly; GO:0007166 cell surface receptor signaling pathway; GO:0051973 positive regulation of telomerase activity; GO:0009891 positive regulation of biosynthetic process; GO:0018212 peptidyl-tyrosine modification; GO:0060271 cilium assembly; GO:0006914 autophagy; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0044782 cilium organization; GO:0008152 metabolic process; GO:0035966 response to topologically incorrect protein; GO:0009408 response to heat; GO:0065003 macromolecular complex assembly; GO:0044093 positive regulation of molecular function; GO:0038127 ERBB signaling pathway; GO:0044770 cell cycle phase transition; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0033365 protein localization to organelle; GO:0051347 positive regulation of transferase activity; GO:0008104 protein localization; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0002443 leukocyte mediated immunity; GO:0072657 protein localization to membrane; GO:0051054 positive regulation of DNA metabolic process; GO:0080090 regulation of primary metabolic process; GO:0071806 protein transmembrane transport; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0031323 regulation of cellular metabolic process; GO:0051341 regulation of oxidoreductase activity; GO:0050776 regulation of immune response; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0080135 regulation of cellular response to stress; GO:0030163 protein catabolic process; GO:0032768 regulation of monooxygenase activity; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:1904407 positive regulation of nitric oxide metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0002682 regulation of immune system process; GO:0006464 cellular protein modification process; GO:0032200 telomere organization; GO:0048010 vascular endothelial growth factor receptor signaling pathway; GO:0000086 G2/M transition of mitotic cell cycle; GO:0072655 establishment of protein localization to mitochondrion; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016310 phosphorylation; GO:0046907 intracellular transport; GO:0002283 neutrophil activation involved in immune response; GO:0007006 mitochondrial membrane organization; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0006259 DNA metabolic process; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0080134 regulation of response to stress; GO:1903047 mitotic cell cycle process; GO:0060249 anatomical structure homeostasis; GO:0045040 protein import into mitochondrial outer membrane; GO:0046483 heterocycle metabolic process; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0051338 regulation of transferase activity; GO:0044248 cellular catabolic process; GO:0006626 protein targeting to mitochondrion; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902580 single-organism cellular localization; GO:0006898 receptor-mediated endocytosis; GO:0038093 Fc receptor signaling pathway; GO:0034613 cellular protein localization; GO:0050778 positive regulation of immune response; GO:0090150 establishment of protein localization to membrane; GO:0006461 protein complex assembly; GO:0044772 mitotic cell cycle phase transition; GO:0002253 activation of immune response; GO:0006986 response to unfolded protein; GO:0006950 response to stress; GO:0016192 vesicle-mediated transport; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0002376 immune system process; GO:0071702 organic substance transport; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0002263 cell activation involved in immune response; GO:2000278 regulation of DNA biosynthetic process; GO:0030031 cell projection assembly; GO:0045184 establishment of protein localization; GO:0055085 transmembrane transport; GO:0045055 regulated exocytosis; GO:0051276 chromosome organization; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0031325 positive regulation of cellular metabolic process; GO:0051972 regulation of telomerase activity; GO:0001775 cell activation; GO:0031647 regulation of protein stability; GO:0044839 cell cycle G2/M phase transition; GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis; GO:0048584 positive regulation of response to stimulus; GO:0043412 macromolecule modification; GO:0006955 immune response; GO:0031328 positive regulation of cellular biosynthetic process; GO:0051179 localization; GO:0050821 protein stabilization; GO:0000723 telomere maintenance; GO:0006887 exocytosis; GO:0072594 establishment of protein localization to organelle; GO:0017038 protein import; GO:0038094 Fc-gamma receptor signaling pathway; GO:0006839 mitochondrial transport; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0010833 telomere maintenance via telomere lengthening; GO:0006796 phosphate-containing compound metabolic process; GO:0006909 phagocytosis; GO:0051234 establishment of localization; GO:1905323 telomerase holoenzyme complex assembly; GO:0031396 regulation of protein ubiquitination; GO:0006457 protein folding; GO:0006605 protein targeting; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0071826 ribonucleoprotein complex subunit organization; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0022607 cellular component assembly; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0007005 mitochondrion organization; GO:0065002 intracellular protein transmembrane transport; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0044743 protein transmembrane import into intracellular organelle; GO:0033036 macromolecule localization; GO:0045429 positive regulation of nitric oxide biosynthetic process; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0002274 myeloid leukocyte activation; GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis; GO:0071822 protein complex subunit organization; GO:0031326 regulation of cellular biosynthetic process; GO:0002446 neutrophil mediated immunity; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0002444 myeloid leukocyte mediated immunity; GO:1902582 single-organism intracellular transport; GO:0018108 peptidyl-tyrosine phosphorylation; GO:1902589 single-organism organelle organization; GO:0043254 regulation of protein complex assembly; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0090304 nucleic acid metabolic process; GO:0051052 regulation of DNA metabolic process; GO:0030030 cell projection organization; GO:0032940 secretion by cell; GO:1900034 regulation of cellular response to heat; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0002431 Fc receptor mediated stimulatory signaling pathway; GO:0043299 leukocyte degranulation; GO:0070271 protein complex biogenesis; GO:0036211 protein modification process; GO:0050999 regulation of nitric-oxide synthase activity; GO:2000377 regulation of reactive oxygen species metabolic process; GO:0042026 protein refolding; GO:0061684 chaperone-mediated autophagy; GO:0007008 outer mitochondrial membrane organization; GO:0016043 cellular component organization; GO:1903428 positive regulation of reactive oxygen species biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0002252 immune effector process; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0046677 response to antibiotic; GO:0044087 regulation of cellular component biogenesis; GO:0097711 ciliary basal body docking; GO:0050896 response to stimulus; GO:0022406 membrane docking; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0006468 protein phosphorylation; GO:0070925 organelle assembly; GO:0090151 establishment of protein localization to mitochondrial membrane; GO:1990542 mitochondrial transmembrane transport; GO:0009266 response to temperature stimulus; GO:0006886 intracellular protein transport; GO:0002757 immune response-activating signal transduction; GO:0034641 cellular nitrogen compound metabolic process; GO:0071897 DNA biosynthetic process; GO:0036230 granulocyte activation; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0043623 cellular protein complex assembly; GO:0034622 cellular macromolecular complex assembly; GO:1903426 regulation of reactive oxygen species biosynthetic process; GO:0043335 protein unfolding; GO:0006807 nitrogen compound metabolic process; GO:0044802 single-organism membrane organization; GO:0010556 regulation of macromolecule biosynthetic process; GO:0007004 telomere maintenance via telomerase; GO:0043312 neutrophil degranulation; GO:0070585 protein localization to mitochondrion; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0043085 positive regulation of catalytic activity; GO:0043933 macromolecular complex subunit organization; GO:0051641 cellular localization; GO:0018193 peptidyl-amino acid modification; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0070727 cellular macromolecule localization; GO:2000379 positive regulation of reactive oxygen species metabolic process; GO:0038128 ERBB2 signaling pathway; GO:0009409 response to cold; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0051246 regulation of protein metabolic process; GO:0009057 macromolecule catabolic process; GO:0002684 positive regulation of immune system process; GO:0051131 chaperone-mediated protein complex assembly; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0022402 cell cycle process; GO:0051128 regulation of cellular component organization; GO:0009056 catabolic process; GO:2000573 positive regulation of DNA biosynthetic process; GO:0007049 cell cycle; GO:0006278 RNA-dependent DNA biosynthetic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0034774 secretory granule lumen; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0032587 ruffle membrane; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0048770 pigment granule; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0031983 vesicle lumen; GO:0098590 plasma membrane region; GO:0070013 intracellular organelle lumen; GO:0031256 leading edge membrane; GO:0043209 myelin sheath; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0030139 endocytic vesicle; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0031252 cell leading edge; GO:0042995 cell projection; GO:0042470 melanosome; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0043202 lysosomal lumen; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0060205 cytoplasmic vesicle lumen; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0001726 ruffle; GO:0031253 cell projection membrane; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0071682 endocytic vesicle lumen; GO:0044428 nuclear part; ","GO:0030235 nitric-oxide synthase regulator activity; GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:1990782 protein tyrosine kinase binding; GO:0070182 DNA polymerase binding; GO:0046983 protein dimerization activity; GO:0019901 protein kinase binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0004713 protein tyrosine kinase activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0004672 protein kinase activity; GO:0098772 molecular function regulator; GO:0003823 antigen binding; GO:0016887 ATPase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0042802 identical protein binding; GO:0042826 histone deacetylase binding; GO:0016462 pyrophosphatase activity; GO:0016301 kinase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0023023 MHC protein complex binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0023026 MHC class II protein complex binding; GO:0030911 TPR domain binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0051020 GTPase binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003723 RNA binding; GO:0005524 ATP binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0044877 macromolecular complex binding; GO:0000166 nucleotide binding; GO:0019900 kinase binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0030234 enzyme regulator activity; GO:0042803 protein homodimerization activity; GO:0003676 nucleic acid binding; GO:0032555 purine ribonucleotide binding; GO:0019904 protein domain specific binding; GO:0051082 unfolded protein binding; GO:0001883 purine nucleoside binding; GO:0019899 enzyme binding; GO:0036094 small molecule binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0032403 protein complex binding; ","K04079","HSP90A; molecular chaperone HtpG","hsa05200 Pathways in cancer - Homo sapiens (human); hsa04657 IL-17 signaling pathway - Homo sapiens (human); hsa04659 Th17 cell differentiation - Homo sapiens (human); hsa04217 Necroptosis - Homo sapiens (human); hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human); hsa04612 Antigen processing and presentation - Homo sapiens (human); hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); hsa05215 Prostate cancer - Homo sapiens (human); hsa04914 Progesterone-mediated oocyte maturation - Homo sapiens (human); hsa04915 Estrogen signaling pathway - Homo sapiens (human); ","IPR020575; IPR020568; IPR003594; ","\"Heat shock protein Hsp90, N-terminal; Ribosomal protein S5 domain 2-type fold; Histidine kinase-like ATPase, C-terminal domain; \"\r"]
["P07902","Galactose-1-phosphate uridylyltransferase OS=Homo sapiens OX=9606 GN=GALT","GALT",43.363,9.0949,11.3,4,4,4,1.089,1.134,1.043,0.883,0.965,0.907,0.844,0.00884,"cyto_nucl\r","GO:0046365 monosaccharide catabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006258 UDP-glucose catabolic process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0006011 UDP-glucose metabolic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009227 nucleotide-sugar catabolic process; GO:0005996 monosaccharide metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0044248 cellular catabolic process; GO:1901361 organic cyclic compound catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0009987 cellular process; GO:0044724 single-organism carbohydrate catabolic process; GO:0044712 single-organism catabolic process; GO:0044281 small molecule metabolic process; GO:1901136 carbohydrate derivative catabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044282 small molecule catabolic process; GO:0044238 primary metabolic process; GO:0005975 carbohydrate metabolic process; GO:0016052 carbohydrate catabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0019388 galactose catabolic process; GO:0009225 nucleotide-sugar metabolic process; GO:0019320 hexose catabolic process; GO:0006012 galactose metabolic process; GO:0009056 catabolic process; GO:0046700 heterocycle catabolic process; GO:0019318 hexose metabolic process; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:0008108 UDP-glucose:hexose-1-phosphate uridylyltransferase activity; GO:0046914 transition metal ion binding; GO:0016779 nucleotidyltransferase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0008270 zinc ion binding; GO:0070569 uridylyltransferase activity; GO:0016740 transferase activity; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K00965","galT; UDPglucose--hexose-1-phosphate uridylyltransferase [EC:2.7.7.12]","hsa04917 Prolactin signaling pathway - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00052 Galactose metabolism - Homo sapiens (human); hsa00520 Amino sugar and nucleotide sugar metabolism - Homo sapiens (human); ","IPR005849; IPR011146; IPR005850; ","\"Galactose-1-phosphate uridyl transferase, N-terminal; HIT-like domain; Galactose-1-phosphate uridyl transferase, C-terminal; \"\r"]
["P07910","Heterogeneous nuclear ribonucleoproteins C1/C2 OS=Homo sapiens OX=9606 GN=HNRNPC","HNRNPC",33.67,87.39,37.9,14,35,14,0.908,0.944,0.877,1.079,1.076,1.073,1.183,0.0157,"nucleus\r","GO:0001649 osteoblast differentiation; GO:0065008 regulation of biological quality; GO:0010608 posttranscriptional regulation of gene expression; GO:0043489 RNA stabilization; GO:0051129 negative regulation of cellular component organization; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0032204 regulation of telomere maintenance; GO:0008152 metabolic process; GO:2000279 negative regulation of DNA biosynthetic process; GO:0043170 macromolecule metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0006396 RNA processing; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0001503 ossification; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0043044 ATP-dependent chromatin remodeling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0032501 multicellular organismal process; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:0010639 negative regulation of organelle organization; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0051052 regulation of DNA metabolic process; GO:0051053 negative regulation of DNA metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0006325 chromatin organization; GO:0016071 mRNA metabolic process; GO:0048255 mRNA stabilization; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0032210 regulation of telomere maintenance via telomerase; GO:0006338 chromatin remodeling; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0032844 regulation of homeostatic process; GO:0032211 negative regulation of telomere maintenance via telomerase; GO:0071704 organic substance metabolic process; GO:0043487 regulation of RNA stability; GO:1904356 regulation of telomere maintenance via telomere lengthening; GO:0000398 mRNA splicing, via spliceosome; GO:0030154 cell differentiation; GO:1904357 negative regulation of telomere maintenance via telomere lengthening; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0070935 3'-UTR-mediated mRNA stabilization; GO:0006807 nitrogen compound metabolic process; GO:0033043 regulation of organelle organization; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0032845 negative regulation of homeostatic process; GO:0044238 primary metabolic process; GO:0043488 regulation of mRNA stability; GO:2000278 regulation of DNA biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0033044 regulation of chromosome organization; GO:0032205 negative regulation of telomere maintenance; GO:0009890 negative regulation of biosynthetic process; GO:2001251 negative regulation of chromosome organization; GO:0051276 chromosome organization; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0010467 gene expression; GO:0051128 regulation of cellular component organization; GO:0031327 negative regulation of cellular biosynthetic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044454 nuclear chromosome part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005694 chromosome; GO:0000790 nuclear chromatin; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005681 spliceosomal complex; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0000785 chromatin; GO:0071013 catalytic step 2 spliceosome; GO:0000228 nuclear chromosome; GO:1990904 ribonucleoprotein complex; GO:0043234 protein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0031490 chromatin DNA binding; GO:0001158 enhancer sequence-specific DNA binding; GO:0003690 double-stranded DNA binding; GO:0005515 protein binding; GO:0003682 chromatin binding; GO:0035326 enhancer binding; GO:0000987 core promoter proximal region sequence-specific DNA binding; GO:0000975 regulatory region DNA binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding; GO:0003729 mRNA binding; GO:0008187 poly-pyrimidine tract binding; GO:0042802 identical protein binding; GO:0005488 binding; GO:0008266 poly(U) RNA binding; GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding; GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding; GO:0003723 RNA binding; GO:0003677 DNA binding; GO:0000976 transcription regulatory region sequence-specific DNA binding; GO:0003730 mRNA 3'-UTR binding; GO:0044877 macromolecular complex binding; GO:0001012 RNA polymerase II regulatory region DNA binding; GO:1990837 sequence-specific double-stranded DNA binding; GO:0000166 nucleotide binding; GO:0043565 sequence-specific DNA binding; GO:1990247 N6-methyladenosine-containing RNA binding; GO:0070034 telomerase RNA binding; GO:0003727 single-stranded RNA binding; GO:0001159 core promoter proximal region DNA binding; GO:0001067 regulatory region nucleic acid binding; GO:0044212 transcription regulatory region DNA binding; GO:0003676 nucleic acid binding; GO:0031491 nucleosome binding; GO:0031492 nucleosomal DNA binding; GO:0036094 small molecule binding; ","K12884","HNRNPC; heterogeneous nuclear ribonucleoprotein C1/C2","hsa03040 Spliceosome - Homo sapiens (human); ","IPR000504; IPR012677; ","RNA recognition motif domain; Nucleotide-binding alpha-beta plait domain; \r"]
["P07919","Cytochrome b-c1 complex subunit 6, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRH","UQCRH",10.739,19.058,46.2,5,9,5,1.029,1.046,1.053,0.973,1.023,0.986,0.953,0.0436,"extracellular\r","GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0006753 nucleoside phosphate metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0044765 single-organism transport; GO:0098655 cation transmembrane transport; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0006119 oxidative phosphorylation; GO:0044763 single-organism cellular process; GO:0072521 purine-containing compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0006810 transport; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0022900 electron transport chain; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0098662 inorganic cation transmembrane transport; GO:0016310 phosphorylation; GO:0034220 ion transmembrane transport; GO:0006725 cellular aromatic compound metabolic process; GO:0042773 ATP synthesis coupled electron transport; GO:0009259 ribonucleotide metabolic process; GO:0022904 respiratory electron transport chain; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:1902578 single-organism localization; GO:0006139 nucleobase-containing compound metabolic process; GO:0006812 cation transport; GO:1901135 carbohydrate derivative metabolic process; GO:1902600 hydrogen ion transmembrane transport; GO:0034641 cellular nitrogen compound metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0009119 ribonucleoside metabolic process; GO:0046034 ATP metabolic process; GO:0098660 inorganic ion transmembrane transport; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0045333 cellular respiration; GO:0006163 purine nucleotide metabolic process; GO:0006818 hydrogen transport; GO:0015992 proton transport; GO:0046128 purine ribonucleoside metabolic process; GO:0055085 transmembrane transport; GO:0006793 phosphorus metabolic process; GO:0009060 aerobic respiration; GO:0006811 ion transport; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0051179 localization; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:0015672 monovalent inorganic cation transport; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0098798 mitochondrial protein complex; GO:0005623 cell; GO:0044455 mitochondrial membrane part; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:1902494 catalytic complex; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005750 mitochondrial respiratory chain complex III; GO:0019866 organelle inner membrane; GO:1990351 transporter complex; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0098803 respiratory chain complex; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0070069 cytochrome complex; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:1902495 transmembrane transporter complex; GO:0045275 respiratory chain complex III; GO:0016021 integral component of membrane; GO:0005739 mitochondrion; GO:0005746 mitochondrial respiratory chain; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:1990204 oxidoreductase complex; GO:0031975 envelope; GO:0043234 protein complex; GO:0070469 respiratory chain; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0008121 ubiquinol-cytochrome-c reductase activity; GO:0015075 ion transmembrane transporter activity; GO:0016679 oxidoreductase activity, acting on diphenols and related substances as donors; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0015077 monovalent inorganic cation transmembrane transporter activity; GO:0015078 hydrogen ion transmembrane transporter activity; GO:0016681 oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor; GO:0022891 substrate-specific transmembrane transporter activity; GO:0016491 oxidoreductase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0022890 inorganic cation transmembrane transporter activity; GO:0008324 cation transmembrane transporter activity; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; ","K00416","QCR6; ubiquinol-cytochrome c reductase subunit 6","hsa04260 Cardiac muscle contraction - Homo sapiens (human); hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); ","IPR023184; ","Ubiquinol-cytochrome C reductase hinge domain; \r"]
["P07942","Laminin subunit beta-1 OS=Homo sapiens OX=9606 GN=LAMB1","LAMB1",198.04,40.223,7.1,10,11,10,1.152,1.073,1.064,0.939,0.877,0.951,0.841,0.00832,"extracellular\r","GO:0030335 positive regulation of cell migration; GO:0051674 localization of cell; GO:0007420 brain development; GO:0040017 positive regulation of locomotion; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0032989 cellular component morphogenesis; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0021987 cerebral cortex development; GO:0021537 telencephalon development; GO:0007492 endoderm development; GO:0022610 biological adhesion; GO:0016337 single organismal cell-cell adhesion; GO:0034446 substrate adhesion-dependent cell spreading; GO:0050678 regulation of epithelial cell proliferation; GO:0032879 regulation of localization; GO:0021885 forebrain cell migration; GO:0007155 cell adhesion; GO:0060322 head development; GO:0030198 extracellular matrix organization; GO:0009790 embryo development; GO:0048598 embryonic morphogenesis; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0009888 tissue development; GO:0001704 formation of primary germ layer; GO:0048699 generation of neurons; GO:0098609 cell-cell adhesion; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0008347 glial cell migration; GO:0048870 cell motility; GO:0051272 positive regulation of cellular component movement; GO:0032501 multicellular organismal process; GO:0042476 odontogenesis; GO:0000902 cell morphogenesis; GO:0022029 telencephalon cell migration; GO:0048513 animal organ development; GO:0042063 gliogenesis; GO:0050789 regulation of biological process; GO:0030030 cell projection organization; GO:0007417 central nervous system development; GO:0098602 single organism cell adhesion; GO:0009887 animal organ morphogenesis; GO:0040011 locomotion; GO:0048856 anatomical structure development; GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration; GO:0021543 pallium development; GO:0050794 regulation of cellular process; GO:0016477 cell migration; GO:0021799 cerebral cortex radially oriented cell migration; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0042127 regulation of cell proliferation; GO:0021795 cerebral cortex cell migration; GO:2000147 positive regulation of cell motility; GO:0048468 cell development; GO:0000904 cell morphogenesis involved in differentiation; GO:0007369 gastrulation; GO:0009653 anatomical structure morphogenesis; GO:0030154 cell differentiation; GO:2000145 regulation of cell motility; GO:0043062 extracellular structure organization; GO:0030900 forebrain development; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0001706 endoderm formation; GO:0021801 cerebral cortex radial glia guided migration; GO:0035987 endodermal cell differentiation; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0030334 regulation of cell migration; GO:0031175 neuron projection development; GO:0048518 positive regulation of biological process; GO:0030182 neuron differentiation; GO:0031589 cell-substrate adhesion; GO:0044767 single-organism developmental process; GO:0006928 movement of cell or subcellular component; GO:0051179 localization; GO:0040012 regulation of locomotion; GO:0022030 telencephalon glial cell migration; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; GO:0050679 positive regulation of epithelial cell proliferation; GO:0008284 positive regulation of cell proliferation; ","GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005606 laminin-1 complex; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0043257 laminin-8 complex; GO:0005623 cell; GO:0044420 extracellular matrix component; GO:0005576 extracellular region; GO:0043256 laminin complex; GO:0005604 basement membrane; GO:0005607 laminin-2 complex; GO:0005605 basal lamina; GO:0031012 extracellular matrix; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0005578 proteinaceous extracellular matrix; GO:0043259 laminin-10 complex; GO:0043227 membrane-bounded organelle; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005201 extracellular matrix structural constituent; GO:0005515 protein binding; GO:0005198 structural molecule activity; GO:0005488 binding; ","K05636","LAMB1; laminin, beta 1","hsa05200 Pathways in cancer - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa05146 Amoebiasis - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa05222 Small cell lung cancer - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa04512 ECM-receptor interaction - Homo sapiens (human); hsa05145 Toxoplasmosis - Homo sapiens (human); ","IPR013015; IPR002049; IPR000742; IPR008211; ","\"Laminin IV type B; Laminin EGF domain; EGF-like domain; Laminin, N-terminal; \"\r"]
["P07948","Tyrosine-protein kinase Lyn OS=Homo sapiens OX=9606 GN=LYN","LYN",58.573,9.9525,8.4,4,7,3,1.041,1.154,0.924,0.968,0.992,0.94,0.93,0.356,"cyto_nucl\r",{"$cut":{"chars":24591,"head":"GO:0044700 single organism signaling; GO:0050672 negative regulation of lymphocyte proliferation; GO:0002694 regulation of leukocyte activation; GO:0010941 regulation of cell death; GO:0014013 regulation of gliogenesis; GO:0018212 peptidyl-tyrosine modification; GO:0031347 regulation of defense response; GO:0044237 cellular metabolic process; GO:0050855 regulation of B cell receptor signaling pathway; GO:0009607 response to biotic stimulus; GO:0030888 regulation of B cell proliferation; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0008152 metabolic process; GO:0070664 negative regulation of leukocyte proliferation; GO:0002532 production of molecular mediator involved in inflammatory response; GO:0044093 positive regulation of molecular function; GO:0034135 regulation of toll-like receptor 2 signaling pathway; GO:0009306 protein secretion; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0080090 regulation of primary metabolic process; GO:0030168 platelet activation; GO:0050864 regulation of B cell activation; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0002520 immune system development; GO:0048870 cell motility; GO:0043086 negative regulation of catalytic activity; GO:0051704 multi-organism process; GO:0071396 cellular response to lipid; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0010243 response to organonitrogen compound; GO:0042063 gliogenesis; GO:0007267 cell-cell signaling; GO:0080135 regulation of cellular response to stress; GO:0002223 stimulatory C-type lectin receptor signaling pathway; GO:1902532 negative regulation of intracellular signal transduction; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0044260 cellular macromolecule metabolic process; GO:2000179 positive regulation of neural precursor cell proliferation; GO:0051223 regulation of protein transport; GO:0002260 lymphocyte homeostasis; GO:0071675 regulation of mononuclear cell migration; GO:0010975 regulation of neuron projection development; GO:0051640 organelle localization; GO:0016310 phosphorylation; GO:0044707 single-multicellular organism process; GO:0043407 negative regulation of MAP kinase activity; GO:0051608 histamine transport; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0002765 immune response-inhibiting signal transduction; GO:0010543 regulation of platelet activation; GO:1901700 response to oxygen-containing compound; GO:0017157 regulation of exocytosis; GO:0002576 platelet degranulation; GO:0048519 negative regulation of biological process; GO:1903706 regulation of hemopoiesis; GO:0042493 response to drug; GO:0050867 positive regulation of cell activation; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0071229 cellular response to acid chemical; GO:2000145 regulation of cell motility; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:0043300 regulation of leukocyte degranulation; GO:0010959 regulation of metal ion transport; GO:1902580 single-organism cellular localization; GO:0038093 Fc receptor signaling pathway; GO:2000668 regulation of dendritic cell apoptotic process; GO:0050778 positive regulation of immune response; GO:0023014 signal transduction by protein phosphorylation; GO:0070668 positive regulation of mast cell proliferation; GO:0051282 regulation of sequestering of calcium ion; GO:0045785 positive regulation of cell adhesion; GO:0006950 response to stress; GO:0032496 response to lipopolysaccharide; GO:0051270 regulation of cellular component movement; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0051924 regulation of calcium ion transport; GO:0032101 regulation of response to external stimulus; GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein; GO:0002376 immune system process; GO:0010033 response to organic substan"}},"GO:0016020 membrane; GO:0044421 extracellular region part; GO:0019898 extrinsic component of membrane; GO:0031090 organelle membrane; GO:0098857 membrane microdomain; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0005913 cell-cell adherens junction; GO:0005887 integral component of plasma membrane; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0009898 cytoplasmic side of plasma membrane; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0005764 lysosome; GO:0098589 membrane region; GO:0014069 postsynaptic density; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0098552 side of membrane; GO:0031226 intrinsic component of plasma membrane; GO:0098797 plasma membrane protein complex; GO:0098802 plasma membrane receptor complex; GO:0031967 organelle envelope; GO:0070161 anchoring junction; GO:0043235 receptor complex; GO:0019897 extrinsic component of plasma membrane; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0098794 postsynapse; GO:0005758 mitochondrial intermembrane space; GO:0030061 mitochondrial crista; GO:0031975 envelope; GO:0005773 vacuole; GO:0043234 protein complex; GO:0099572 postsynaptic specialization; GO:0031966 mitochondrial membrane; GO:0043230 extracellular organelle; GO:0098636 protein complex involved in cell adhesion; GO:0030054 cell junction; GO:0098796 membrane protein complex; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005911 cell-cell junction; GO:0031234 extrinsic component of cytoplasmic side of plasma membrane; GO:0098562 cytoplasmic side of membrane; GO:0032279 asymmetric synapse; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:0031970 organelle envelope lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0019866 organelle inner membrane; GO:0042629 mast cell granule; GO:0048471 perinuclear region of cytoplasm; GO:0045121 membrane raft; GO:0098984 neuron to neuron synapse; GO:0044456 synapse part; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0008305 integrin complex; GO:0034666 integrin alpha2-beta1 complex; GO:0005829 cytosol; GO:0016021 integral component of membrane; GO:0045202 synapse; GO:0043226 organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0031625 ubiquitin protein ligase binding; GO:0043208 glycosphingolipid binding; GO:0005102 receptor binding; GO:0046625 sphingolipid binding; GO:0004716 signal transducer, downstream of receptor, with protein tyrosine kinase activity; GO:0043015 gamma-tubulin binding; GO:0004713 protein tyrosine kinase activity; GO:0005178 integrin binding; GO:0005515 protein binding; GO:0004672 protein kinase activity; GO:0004871 signal transducer activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0005161 platelet-derived growth factor receptor binding; GO:0008092 cytoskeletal protein binding; GO:0016301 kinase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0008289 lipid binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0015631 tubulin binding; GO:0070851 growth factor receptor binding; GO:0000166 nucleotide binding; GO:0017124 SH3 domain binding; GO:0051219 phosphoprotein binding; GO:0050839 cell adhesion molecule binding; GO:0032549 ribonucleoside binding; GO:0005057 signal transducer activity, downstream of receptor; GO:0004715 non-membrane spanning protein tyrosine kinase activity; GO:0051861 glycolipid binding; GO:0097367 carbohydrate derivative binding; GO:0044325 ion channel binding; GO:0019904 protein domain specific binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0019899 enzyme binding; GO:0032403 protein complex binding; GO:0036094 small molecule binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K05854","LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]","hsa05120 Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human); hsa04666 Fc gamma R-mediated phagocytosis - Homo sapiens (human); hsa04664 Fc epsilon RI signaling pathway - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); hsa04662 B cell receptor signaling pathway - Homo sapiens (human); hsa05167 Kaposi's sarcoma-associated herpesvirus infection - Homo sapiens (human); hsa05203 Viral carcinogenesis - Homo sapiens (human); hsa04730 Long-term depression - Homo sapiens (human); hsa04611 Platelet activation - Homo sapiens (human); hsa04062 Chemokine signaling pathway - Homo sapiens (human); hsa04064 NF-kappa B signaling pathway - Homo sapiens (human); ","IPR000980; IPR001452; IPR000719; IPR001245; IPR020635; IPR011009; ","\"SH2 domain; SH3 domain; Protein kinase domain; Serine-threonine/tyrosine-protein kinase catalytic domain; Tyrosine-protein kinase, catalytic domain; Protein kinase-like domain; \"\r"]
["P07954","Fumarate hydratase, mitochondrial OS=Homo sapiens OX=9606 GN=FH","FH",54.636,99.832,39,15,30,15,1.042,0.912,1.013,1.009,1.011,0.969,1.007,0.847,"mitochondria\r","GO:0043648 dicarboxylic acid metabolic process; GO:0044707 single-multicellular organism process; GO:0065008 regulation of biological quality; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0048871 multicellular organismal homeostasis; GO:0060249 anatomical structure homeostasis; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0009987 cellular process; GO:0006106 fumarate metabolic process; GO:0072350 tricarboxylic acid metabolic process; GO:0048873 homeostasis of number of cells within a tissue; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006099 tricarboxylic acid cycle; GO:0044238 primary metabolic process; GO:0032501 multicellular organismal process; GO:0045333 cellular respiration; GO:0048872 homeostasis of number of cells; GO:0006101 citrate metabolic process; GO:0044710 single-organism metabolic process; GO:0009060 aerobic respiration; GO:0015980 energy derivation by oxidation of organic compounds; GO:0001894 tissue homeostasis; GO:0006108 malate metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0006082 organic acid metabolic process; GO:0043436 oxoacid metabolic process; GO:0065007 biological regulation; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0045239 tricarboxylic acid cycle enzyme complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0003824 catalytic activity; GO:0005488 binding; GO:0004333 fumarate hydratase activity; GO:0016829 lyase activity; GO:0016836 hydro-lyase activity; GO:0005515 protein binding; GO:0016835 carbon-oxygen lyase activity; ","K01679","E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]","hsa05200 Pathways in cancer - Homo sapiens (human); hsa04934 Cushing's syndrome - Homo sapiens (human); hsa00620 Pyruvate metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00020 Citrate cycle (TCA cycle) - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); hsa05211 Renal cell carcinoma - Homo sapiens (human); ","IPR024083; IPR008948; IPR022761; IPR018951; ","\"Fumarase/histidase, N-terminal; L-Aspartase-like; Fumarate lyase, N-terminal; Fumarase C, C-terminal; \"\r"]
["P08123","Collagen alpha-2(I) chain OS=Homo sapiens OX=9606 GN=COL1A2","COL1A2",129.31,318.03,24.3,30,62,30,1.14,1.166,1.106,0.841,0.876,0.871,0.758,0.000158,"extracellular\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0001101 response to acid chemical; GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0051674 localization of cell; GO:0030199 collagen fibril organization; GO:0007166 cell surface receptor signaling pathway; GO:0001568 blood vessel development; GO:0071560 cellular response to transforming growth factor beta stimulus; GO:0044236 multicellular organism metabolic process; GO:0044699 single-organism process; GO:0071363 cellular response to growth factor stimulus; GO:0009611 response to wounding; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0065003 macromolecular complex assembly; GO:0009719 response to endogenous stimulus; GO:0007266 Rho protein signal transduction; GO:0070848 response to growth factor; GO:0043170 macromolecule metabolic process; GO:0030198 extracellular matrix organization; GO:0044259 multicellular organismal macromolecule metabolic process; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0070887 cellular response to chemical stimulus; GO:0030574 collagen catabolic process; GO:0032502 developmental process; GO:0043200 response to amino acid; GO:0051716 cellular response to stimulus; GO:0043588 skin development; GO:0071822 protein complex subunit organization; GO:0030168 platelet activation; GO:0044763 single-organism cellular process; GO:0001944 vasculature development; GO:0048870 cell motility; GO:0007264 small GTPase mediated signal transduction; GO:0071559 response to transforming growth factor beta; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0050776 regulation of immune response; GO:0042476 odontogenesis; GO:0071417 cellular response to organonitrogen compound; GO:0051291 protein heterooligomerization; GO:0010243 response to organonitrogen compound; GO:0048513 animal organ development; GO:0050900 leukocyte migration; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:1901699 cellular response to nitrogen compound; GO:0044710 single-organism metabolic process; GO:0071230 cellular response to amino acid stimulus; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0009887 animal organ morphogenesis; GO:0002682 regulation of immune system process; GO:0040011 locomotion; GO:0050817 coagulation; GO:0070271 protein complex biogenesis; GO:0003013 circulatory system process; GO:0097435 supramolecular fiber organization; GO:0048856 anatomical structure development; GO:0001501 skeletal system development; GO:0007265 Ras protein signal transduction; GO:0043589 skin morphogenesis; GO:0008217 regulation of blood pressure; GO:0072359 circulatory system development; GO:0050794 regulation of cellular process; GO:0016477 cell migration; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0071310 cellular response to organic substance; GO:1901700 response to oxygen-containing compound; GO:0050896 response to stimulus; GO:0007599 hemostasis; GO:0051259 protein oligomerization; GO:0071704 organic substance metabolic process; GO:0009653 anatomical structure morphogenesis; GO:0044243 multicellular organismal catabolic process; GO:0071229 cellular response to acid chemical; GO:0043062 extracellular structure organization; GO:0008015 blood circulation; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0070206 protein trimerization; GO:0050878 regulation of body fluid levels; GO:0003008 system process; GO:0006950 response to stress; GO:0035556 intracellular signal transduction; GO:0048731 system development; GO:0044712 single-organism catabolic process; GO:0007179 transforming growth factor beta receptor signaling pathway; GO:0002376 immune system process; GO:0072358 cardiovascular system development; GO:0010033 response to organic substance; GO:0070208 protein heterotrimerization; GO:0043933 macromolecular complex subunit organization; GO:1901701 cellular response to oxygen-containing compound; GO:0042060 wound healing; GO:0071495 cellular response to endogenous stimulus; GO:0044767 single-organism developmental process; GO:0032963 collagen metabolic process; GO:0006928 movement of cell or subcellular component; GO:0001775 cell activation; GO:0051179 localization; GO:0009056 catabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0005584 collagen type I trimer; GO:0005615 extracellular space; GO:0005783 endoplasmic reticulum; GO:0044421 extracellular region part; GO:0098643 banded collagen fibril; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0005583 fibrillar collagen trimer; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0099512 supramolecular fiber; GO:0005623 cell; GO:0099080 supramolecular complex; GO:0044420 extracellular matrix component; GO:0044422 organelle part; GO:0005581 collagen trimer; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0005788 endoplasmic reticulum lumen; GO:0043229 intracellular organelle; GO:0098644 complex of collagen trimers; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0099081 supramolecular polymer; GO:0031012 extracellular matrix; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044432 endoplasmic reticulum part; GO:0005578 proteinaceous extracellular matrix; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005201 extracellular matrix structural constituent; GO:0030674 protein binding, bridging; GO:0042802 identical protein binding; GO:0019838 growth factor binding; GO:0005488 binding; GO:0043167 ion binding; GO:0048407 platelet-derived growth factor binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0060090 binding, bridging; GO:0046332 SMAD binding; GO:0005198 structural molecule activity; ","K06236","COL1A; collagen, type I, alpha","hsa04933 AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa05146 Amoebiasis - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa04611 Platelet activation - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa04512 ECM-receptor interaction - Homo sapiens (human); hsa04974 Protein digestion and absorption - Homo sapiens (human); hsa04926 Relaxin signaling pathway - Homo sapiens (human); ","IPR000885; ","\"Fibrillar collagen, C-terminal; \"\r"]
["P08133","Annexin A6 OS=Homo sapiens OX=9606 GN=ANXA6","ANXA6",75.872,278.99,65.5,46,109,46,1.129,1.092,1.139,0.883,0.894,0.877,0.79,7.65e-05,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0016043 cellular component organization; GO:0065008 regulation of biological quality; GO:0072511 divalent inorganic cation transport; GO:0072503 cellular divalent inorganic cation homeostasis; GO:0034220 ion transmembrane transport; GO:0097190 apoptotic signaling pathway; GO:0051260 protein homooligomerization; GO:0030001 metal ion transport; GO:0030003 cellular cation homeostasis; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0055082 cellular chemical homeostasis; GO:0051239 regulation of multicellular organismal process; GO:0051259 protein oligomerization; GO:0051234 establishment of localization; GO:0042592 homeostatic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0006816 calcium ion transport; GO:0006812 cation transport; GO:0055080 cation homeostasis; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0006915 apoptotic process; GO:0055065 metal ion homeostasis; GO:0044057 regulation of system process; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0006461 protein complex assembly; GO:0051716 cellular response to stimulus; GO:0071822 protein complex subunit organization; GO:0050801 ion homeostasis; GO:0055074 calcium ion homeostasis; GO:0098771 inorganic ion homeostasis; GO:0006937 regulation of muscle contraction; GO:0044763 single-organism cellular process; GO:0051560 mitochondrial calcium ion homeostasis; GO:0019725 cellular homeostasis; GO:0090257 regulation of muscle system process; GO:0023052 signaling; GO:0006874 cellular calcium ion homeostasis; GO:0043933 macromolecular complex subunit organization; GO:0006810 transport; GO:0055085 transmembrane transport; GO:0050789 regulation of biological process; GO:0006873 cellular ion homeostasis; GO:0008219 cell death; GO:0006811 ion transport; GO:0006875 cellular metal ion homeostasis; GO:0012501 programmed cell death; GO:0051179 localization; GO:0070271 protein complex biogenesis; GO:0072507 divalent inorganic cation homeostasis; GO:0070838 divalent metal ion transport; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0048770 pigment granule; GO:0005765 lysosomal membrane; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0031902 late endosome membrane; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005764 lysosome; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0005768 endosome; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0000323 lytic vacuole; GO:0010008 endosome membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0005770 late endosome; GO:0098588 bounding membrane of organelle; GO:0042470 melanosome; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0044440 endosomal part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0032934 sterol binding; GO:0046983 protein dimerization activity; GO:0022803 passive transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0048306 calcium-dependent protein binding; GO:0005496 steroid binding; GO:0015267 channel activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0042802 identical protein binding; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0008289 lipid binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0005216 ion channel activity; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005215 transporter activity; GO:0015276 ligand-gated ion channel activity; GO:0005544 calcium-dependent phospholipid binding; GO:0022834 ligand-gated channel activity; GO:0015485 cholesterol binding; GO:0015075 ion transmembrane transporter activity; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0000166 nucleotide binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0022838 substrate-specific channel activity; GO:0043178 alcohol binding; GO:0042803 protein homodimerization activity; GO:0005543 phospholipid binding; GO:0046872 metal ion binding; GO:0032555 purine ribonucleotide binding; GO:0022836 gated channel activity; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0005509 calcium ion binding; GO:0099600 transmembrane receptor activity; GO:0022857 transmembrane transporter activity; GO:0036094 small molecule binding; ","K17094"]
["P08134","Rho-related GTP-binding protein RhoC OS=Homo sapiens OX=9606 GN=RHOC","RHOC",22.006,8.8279,32.6,6,13,1,1.008,1.103,1.017,0.983,0.934,0.971,0.923,0.0716,"cytoplasm\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0051674 localization of cell; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0045216 cell-cell junction organization; GO:0044699 single-organism process; GO:0009611 response to wounding; GO:0048729 tissue morphogenesis; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling; GO:0044093 positive regulation of molecular function; GO:0051056 regulation of small GTPase mediated signal transduction; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0060429 epithelium development; GO:0009888 tissue development; GO:0090505 epiboly involved in wound healing; GO:0060191 regulation of lipase activity; GO:0090504 epiboly; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0048870 cell motility; GO:0007264 small GTPase mediated signal transduction; GO:0023052 signaling; GO:0044319 wound healing, spreading of cells; GO:0060193 positive regulation of lipase activity; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:1902766 skeletal muscle satellite cell migration; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0065009 regulation of molecular function; GO:0051301 cell division; GO:0040011 locomotion; GO:0048856 anatomical structure development; GO:0050794 regulation of cellular process; GO:0034329 cell junction assembly; GO:0016043 cellular component organization; GO:0002009 morphogenesis of an epithelium; GO:0016477 cell migration; GO:0050896 response to stimulus; GO:0009653 anatomical structure morphogenesis; GO:0000910 cytokinesis; GO:0051345 positive regulation of hydrolase activity; GO:0023056 positive regulation of signaling; GO:0010647 positive regulation of cell communication; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:0043297 apical junction assembly; GO:0007043 cell-cell junction assembly; GO:1902531 regulation of intracellular signal transduction; GO:0006950 response to stress; GO:0035556 intracellular signal transduction; GO:0002011 morphogenesis of an epithelial sheet; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0034330 cell junction organization; GO:0042060 wound healing; GO:0044767 single-organism developmental process; GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling; GO:0006928 movement of cell or subcellular component; GO:0009967 positive regulation of signal transduction; GO:0022402 cell cycle process; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0007049 cell cycle; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0097610 cell surface furrow; GO:0071944 cell periphery; GO:0032153 cell division site; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0032155 cell division site part; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0009986 cell surface; GO:0032154 cleavage furrow; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0004871 signal transducer activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0036094 small molecule binding; ","K07857",null,null,"IPR005225; IPR027417; ","Small GTP-binding protein domain; P-loop containing nucleoside triphosphate hydrolase; \r"]
["P08138","Tumor necrosis factor receptor superfamily member 16 OS=Homo sapiens OX=9606 GN=NGFR","NGFR",45.183,2.6882,2.8,1,1,1,0.853,0.98,0.968,1.047,0.954,1.195,1.141,0.176,"extracellular\r","GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0042593 glucose homeostasis; GO:0009891 positive regulation of biosynthetic process; GO:0009607 response to biotic stimulus; GO:0010466 negative regulation of peptidase activity; GO:0008152 metabolic process; GO:0044093 positive regulation of molecular function; GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis; GO:0046324 regulation of glucose import; GO:0052548 regulation of endopeptidase activity; GO:0051716 cellular response to stimulus; GO:0010950 positive regulation of endopeptidase activity; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0043086 negative regulation of catalytic activity; GO:1901343 negative regulation of vasculature development; GO:0006935 chemotaxis; GO:0033209 tumor necrosis factor-mediated signaling pathway; GO:0051704 multi-organism process; GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0006810 transport; GO:0048583 regulation of response to stimulus; GO:0045665 negative regulation of neuron differentiation; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010721 negative regulation of cell development; GO:0060548 negative regulation of cell death; GO:0010975 regulation of neuron projection development; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0044707 single-multicellular organism process; GO:0097190 apoptotic signaling pathway; GO:2001056 positive regulation of cysteine-type endopeptidase activity; GO:1901700 response to oxygen-containing compound; GO:0048519 negative regulation of biological process; GO:0009653 anatomical structure morphogenesis; GO:0051345 positive regulation of hydrolase activity; GO:0050772 positive regulation of axonogenesis; GO:0009889 regulation of biosynthetic process; GO:0031345 negative regulation of cell projection organization; GO:0033500 carbohydrate homeostasis; GO:1902680 positive regulation of RNA biosynthetic process; GO:0001936 regulation of endothelial cell proliferation; GO:0034613 cellular protein localization; GO:0048878 chemical homeostasis; GO:0010771 negative regulation of cell morphogenesis involved in differentiation; GO:0045861 negative regulation of proteolysis; GO:0006950 response to stress; GO:0032496 response to lipopolysaccharide; GO:0051960 regulation of nervous system development; GO:0060284 regulation of cell development; GO:0002376 immune system process; GO:0010977 negative regulation of neuron projection development; GO:0010033 response to organic substance; GO:0032922 circadian regulation of gene expression; GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:1900182 positive regulation of protein localization to nucleus; GO:0031325 positive regulation of cellular metabolic process; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:0006955 immune response; GO:1903827 regulation of cellular protein localization; GO:0051093 negative regulation of developmental process; GO:0048011 neurotrophin TRK receptor signaling pathway; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:1903671 negative regulation of sprouting angiogenesis; GO:0009893 positive regulation of metabolic process; GO:0032990 cell part morphogenesis; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0006915 apoptotic process; GO:0048858 cell projection morphogenesis; GO:0034612 response to tumor necrosis factor; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0010827 regulation of glucose transport; GO:0050771 negative regulation of axonogenesis; GO:0033036 macromolecule localization; GO:0034097 response to cytokine; GO:0031326 regulation of cellular biosynthetic process; GO:2000116 regulation of cysteine-type endopeptidase activity; GO:0002237 response to molecule of bacterial origin; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0038179 neurotrophin signaling pathway; GO:0010942 positive regulation of cell death; GO:0007623 circadian rhythm; GO:0016525 negative regulation of angiogenesis; GO:0045664 regulation of neuron differentiation; GO:0006954 inflammatory response; GO:1902893 regulation of pri-miRNA transcription from RNA polymerase II promoter; GO:1900180 regulation of protein localization to nucleus; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0006952 defense response; GO:0016043 cellular component organization; GO:0043069 negative regulation of programmed cell death; GO:1903829 positive regulation of cellular protein localization; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0010770 positive regulation of cell morphogenesis involved in differentiation; GO:0043065 positive regulation of apoptotic process; GO:1900076 regulation of cellular response to insulin stimulus; GO:0051707 response to other organism; GO:0051346 negative regulation of hydrolase activity; GO:0071704 organic substance metabolic process; GO:0000904 cell morphogenesis involved in differentiation; GO:0033993 response to lipid; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:0045862 positive regulation of proteolysis; GO:0051961 negative regulation of nervous system development; GO:0043066 negative regulation of apoptotic process; GO:0006886 intracellular protein transport; GO:0019221 cytokine-mediated signaling pathway; GO:0045595 regulation of cell differentiation; GO:0006355 regulation of transcription, DNA-templated; GO:0035556 intracellular signal transduction; GO:0051049 regulation of transport; GO:1901342 regulation of vasculature development; GO:0043085 positive regulation of catalytic activity; GO:0008219 cell death; GO:0051248 negative regulation of protein metabolic process; GO:0042981 regulation of apoptotic process; GO:0050767 regulation of neurogenesis; GO:0071840 cellular component organization or biogenesis; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0007166 cell surface receptor signaling pathway; GO:0032989 cellular component morphogenesis; GO:0031293 membrane protein intracellular domain proteolysis; GO:0071345 cellular response to cytokine stimulus; GO:0015031 protein transport; GO:0008285 negative regulation of cell proliferation; GO:0009605 response to external stimulus; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0050678 regulation of epithelial cell proliferation; GO:0070848 response to growth factor; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0008104 protein localization; GO:2001273 regulation of glucose import in response to insulin stimulus; GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0007399 nervous system development; GO:0031346 positive regulation of cell projection organization; GO:0045893 positive regulation of transcription, DNA-templated; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0048812 neuron projection morphogenesis; GO:0007264 small GTPase mediated signal transduction; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0000902 cell morphogenesis; GO:0050768 negative regulation of neurogenesis; GO:1903506 regulation of nucleic acid-templated transcription; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0042330 taxis; GO:0045765 regulation of angiogenesis; GO:0051094 positive regulation of developmental process; GO:0043068 positive regulation of programmed cell death; GO:0010952 positive regulation of peptidase activity; GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0010951 negative regulation of endopeptidase activity; GO:0042127 regulation of cell proliferation; GO:0043067 regulation of programmed cell death; GO:0048523 negative regulation of cellular process; GO:0051239 regulation of multicellular organismal process; GO:0045597 positive regulation of cell differentiation; GO:0060341 regulation of cellular localization; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0010628 positive regulation of gene expression; GO:0007409 axonogenesis; GO:0051171 regulation of nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0032880 regulation of protein localization; GO:0009617 response to bacterium; GO:0051254 positive regulation of RNA metabolic process; GO:0048731 system development; GO:0071702 organic substance transport; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0050770 regulation of axonogenesis; GO:0045184 establishment of protein localization; GO:0030182 neuron differentiation; GO:0051247 positive regulation of protein metabolic process; GO:0097485 neuron projection guidance; GO:0010976 positive regulation of neuron projection development; GO:0006928 movement of cell or subcellular component; GO:0050769 positive regulation of neurogenesis; GO:0012501 programmed cell death; GO:0031328 positive regulation of cellular biosynthetic process; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter; GO:0045666 positive regulation of neuron differentiation; GO:0051129 negative regulation of cellular component organization; GO:0022008 neurogenesis; GO:0051241 negative regulation of multicellular organismal process; GO:0071363 cellular response to growth factor stimulus; GO:0033619 membrane protein proteolysis; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0001937 negative regulation of endothelial cell proliferation; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0007266 Rho protein signal transduction; GO:0010720 positive regulation of cell development; GO:0045596 negative regulation of cell differentiation; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:2000181 negative regulation of blood vessel morphogenesis; GO:0010468 regulation of gene expression; GO:0051962 positive regulation of nervous system development; GO:0048522 positive regulation of cellular process; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0030030 cell projection organization; GO:0019222 regulation of metabolic process; GO:0040011 locomotion; GO:0052547 regulation of peptidase activity; GO:0050680 negative regulation of epithelial cell proliferation; GO:0048856 anatomical structure development; GO:0007265 Ras protein signal transduction; GO:2000026 regulation of multicellular organismal development; GO:1903670 regulation of sprouting angiogenesis; GO:0071356 cellular response to tumor necrosis factor; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031344 regulation of cell projection organization; GO:0031324 negative regulation of cellular metabolic process; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0007411 axon guidance; GO:0048468 cell development; GO:2000117 negative regulation of cysteine-type endopeptidase activity; GO:0006508 proteolysis; GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0009987 cellular process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0031175 neuron projection development; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0051641 cellular localization; GO:0061564 axon development; GO:0070727 cellular macromolecule localization; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0048511 rhythmic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0051128 regulation of cellular component organization; GO:0022604 regulation of cell morphogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0043005 neuron projection; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0031226 intrinsic component of plasma membrane; GO:0042995 cell projection; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0009986 cell surface; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0031267 small GTPase binding; GO:0038023 signaling receptor activity; GO:0031625 ubiquitin protein ligase binding; GO:0005035 death receptor activity; GO:0048406 nerve growth factor binding; GO:0019838 growth factor binding; GO:0015026 coreceptor activity; GO:0005515 protein binding; GO:0004888 transmembrane signaling receptor activity; GO:0005516 calmodulin binding; GO:0004871 signal transducer activity; GO:0017137 Rab GTPase binding; GO:0060089 molecular transducer activity; GO:0043121 neurotrophin binding; GO:0004872 receptor activity; GO:0017016 Ras GTPase binding; GO:0005031 tumor necrosis factor-activated receptor activity; GO:0005488 binding; GO:0051020 GTPase binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0019899 enzyme binding; GO:0099600 transmembrane receptor activity; ","K02583","NGFR; nerve growth factor receptor (TNFR superfamily member 16)","hsa04015 Rap1 signaling pathway - Homo sapiens (human); hsa04722 Neurotrophin signaling pathway - Homo sapiens (human); hsa04014 Ras signaling pathway - Homo sapiens (human); hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa04010 MAPK signaling pathway - Homo sapiens (human); hsa04215 Apoptosis - multiple species - Homo sapiens (human); hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human); ","IPR001368; IPR000488; IPR034046; IPR011029; ","\"TNFR/NGFR cysteine-rich region; Death domain; Tumor necrosis factor receptor 16, N-terminal; Death-like domain; \"\r"]
["P08174","Complement decay-accelerating factor OS=Homo sapiens OX=9606 GN=CD55","CD55",41.4,25.695,18.1,7,10,7,1.153,1.177,1.039,0.893,0.831,0.925,0.786,0.00856,"extracellular\r","GO:0044409 entry into host; GO:0002694 regulation of leukocyte activation; GO:0065008 regulation of biological quality; GO:0016064 immunoglobulin mediated immune response; GO:0032944 regulation of mononuclear cell proliferation; GO:0045321 leukocyte activation; GO:0002698 negative regulation of immune effector process; GO:1903318 negative regulation of protein maturation; GO:0045916 negative regulation of complement activation; GO:0031347 regulation of defense response; GO:0006956 complement activation; GO:2000561 regulation of CD4-positive, alpha-beta T cell proliferation; GO:0008152 metabolic process; GO:0032946 positive regulation of mononuclear cell proliferation; GO:0055065 metal ion homeostasis; GO:0006958 complement activation, classical pathway; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0044419 interspecies interaction between organisms; GO:0002367 cytokine production involved in immune response; GO:0046718 viral entry into host cell; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0002443 leukocyte mediated immunity; GO:0046641 positive regulation of alpha-beta T cell proliferation; GO:0080090 regulation of primary metabolic process; GO:0002456 T cell mediated immunity; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0050670 regulation of lymphocyte proliferation; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0006874 cellular calcium ion homeostasis; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0044710 single-organism metabolic process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0048583 regulation of response to stimulus; GO:0046634 regulation of alpha-beta T cell activation; GO:0002682 regulation of immune system process; GO:1903317 regulation of protein maturation; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0044707 single-multicellular organism process; GO:0030449 regulation of complement activation; GO:2000257 regulation of protein activation cascade; GO:0002283 neutrophil activation involved in immune response; GO:0042127 regulation of cell proliferation; GO:0051806 entry into cell of other organism involved in symbiotic interaction; GO:0002920 regulation of humoral immune response; GO:0010955 negative regulation of protein processing; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0019724 B cell mediated immunity; GO:2000258 negative regulation of protein activation cascade; GO:0050867 positive regulation of cell activation; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway; GO:0002449 lymphocyte mediated immunity; GO:2000516 positive regulation of CD4-positive, alpha-beta T cell activation; GO:0009966 regulation of signal transduction; GO:0050778 positive regulation of immune response; GO:0048878 chemical homeostasis; GO:0002253 activation of immune response; GO:0045861 negative regulation of proteolysis; GO:0045785 positive regulation of cell adhesion; GO:0006950 response to stress; GO:0043900 regulation of multi-organism process; GO:0016192 vesicle-mediated transport; GO:0072376 protein activation cascade; GO:0032101 regulation of response to external stimulus; GO:0002376 immune system process; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:1903039 positive regulation of leukocyte cell-cell adhesion; GO:0009892 negative regulation of metabolic process; GO:0002263 cell activation involved in immune response; GO:0030155 regulation of cell adhesion; GO:0002696 positive regulation of leukocyte activation; GO:0045055 regulated exocytosis; GO:0006873 cellular ion homeostasis; GO:0001816 cytokine production; GO:0050870 positive regulation of T cell activation; GO:0045730 respiratory burst; GO:0070613 regulation of protein processing; GO:0001775 cell activation; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0007204 positive regulation of cytosolic calcium ion concentration; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0006955 immune response; GO:0008284 positive regulation of cell proliferation; GO:0006887 exocytosis; GO:0050863 regulation of T cell activation; GO:0072503 cellular divalent inorganic cation homeostasis; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0051249 regulation of lymphocyte activation; GO:0046635 positive regulation of alpha-beta T cell activation; GO:0051234 establishment of localization; GO:0051649 establishment of localization in cell; GO:0010646 regulation of cell communication; GO:0050671 positive regulation of lymphocyte proliferation; GO:0002250 adaptive immune response; GO:0070663 regulation of leukocyte proliferation; GO:0050777 negative regulation of immune response; GO:0002697 regulation of immune effector process; GO:0002274 myeloid leukocyte activation; GO:0010468 regulation of gene expression; GO:0050801 ion homeostasis; GO:0055074 calcium ion homeostasis; GO:0002446 neutrophil mediated immunity; GO:0098771 inorganic ion homeostasis; GO:0019725 cellular homeostasis; GO:0048522 positive regulation of cellular process; GO:0051251 positive regulation of lymphocyte activation; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0002444 myeloid leukocyte mediated immunity; GO:0002683 negative regulation of immune system process; GO:0030260 entry into host cell; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0050865 regulation of cell activation; GO:0002440 production of molecular mediator of immune response; GO:0032940 secretion by cell; GO:0051828 entry into other organism involved in symbiotic interaction; GO:0019222 regulation of metabolic process; GO:0043299 leukocyte degranulation; GO:0006952 defense response; GO:0072507 divalent inorganic cation homeostasis; GO:0002831 regulation of response to biotic stimulus; GO:0042102 positive regulation of T cell proliferation; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0030003 cellular cation homeostasis; GO:0051480 regulation of cytosolic calcium ion concentration; GO:0048193 Golgi vesicle transport; GO:0002673 regulation of acute inflammatory response; GO:0006959 humoral immune response; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0002921 negative regulation of humoral immune response; GO:0055082 cellular chemical homeostasis; GO:0045087 innate immune response; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0055080 cation homeostasis; GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation; GO:0016032 viral process; GO:0036230 granulocyte activation; GO:2000514 regulation of CD4-positive, alpha-beta T cell activation; GO:0009987 cellular process; GO:0046640 regulation of alpha-beta T cell proliferation; GO:0010629 negative regulation of gene expression; GO:0022409 positive regulation of cell-cell adhesion; GO:0042129 regulation of T cell proliferation; GO:0002369 T cell cytokine production; GO:0048585 negative regulation of response to stimulus; GO:0051701 interaction with host; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0022407 regulation of cell-cell adhesion; GO:0051641 cellular localization; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0070665 positive regulation of leukocyte proliferation; GO:0051246 regulation of protein metabolic process; GO:0002684 positive regulation of immune system process; GO:0050727 regulation of inflammatory response; GO:0035743 CD4-positive, alpha-beta T cell cytokine production; GO:0051248 negative regulation of protein metabolic process; GO:0006875 cellular metal ion homeostasis; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0098857 membrane microdomain; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0098805 whole membrane; GO:0099503 secretory vesicle; GO:0098589 membrane region; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0030141 secretory granule; GO:0045121 membrane raft; GO:0043227 membrane-bounded organelle; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0031226 intrinsic component of plasma membrane; GO:0098588 bounding membrane of organelle; GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane; GO:0070820 tertiary granule; GO:0031225 anchored component of membrane; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0030667 secretory granule membrane; GO:0044459 plasma membrane part; GO:0101003 ficolin-1-rich granule membrane; GO:0005793 endoplasmic reticulum-Golgi intermediate compartment; GO:0009986 cell surface; GO:0030133 transport vesicle; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0008289 lipid binding; GO:0060089 molecular transducer activity; GO:0005515 protein binding; GO:0004872 receptor activity; GO:0001618 virus receptor activity; GO:0005488 binding; ","K04006","DAF; decay accelerating factor","hsa04610 Complement and coagulation cascades - Homo sapiens (human); hsa04640 Hematopoietic cell lineage - Homo sapiens (human); hsa05416 Viral myocarditis - Homo sapiens (human); ","IPR000436; ","Sushi/SCR/CCP domain; \r"]
["P08185","Corticosteroid-binding globulin OS=Homo sapiens OX=9606 GN=SERPINA6","SERPINA6",45.14,17.282,11.4,4,5,4,1.019,0.922,0.968,1.002,1.074,1.048,1.074,0.112,"plasma membrane\r","GO:0050794 regulation of cellular process; GO:0010951 negative regulation of endopeptidase activity; GO:0060255 regulation of macromolecule metabolic process; GO:0044699 single-organism process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0051346 negative regulation of hydrolase activity; GO:0051234 establishment of localization; GO:0071704 organic substance metabolic process; GO:0010466 negative regulation of peptidase activity; GO:0008152 metabolic process; GO:0006629 lipid metabolic process; GO:0008211 glucocorticoid metabolic process; GO:0052548 regulation of endopeptidase activity; GO:0045861 negative regulation of proteolysis; GO:0080090 regulation of primary metabolic process; GO:0008202 steroid metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0009892 negative regulation of metabolic process; GO:0006810 transport; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0051246 regulation of protein metabolic process; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0019222 regulation of metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0052547 regulation of peptidase activity; GO:0051179 localization; GO:0065007 biological regulation; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:0097159 organic cyclic compound binding; GO:0004867 serine-type endopeptidase inhibitor activity; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0030414 peptidase inhibitor activity; GO:0061134 peptidase regulator activity; GO:0008289 lipid binding; GO:0061135 endopeptidase regulator activity; GO:0098772 molecular function regulator; GO:0004857 enzyme inhibitor activity; GO:0004866 endopeptidase inhibitor activity; GO:0005496 steroid binding; ","K04525",null,null,"IPR023796; ","Serpin domain; \r"]
["P08195","4F2 cell-surface antigen heavy chain OS=Homo sapiens OX=9606 GN=SLC3A2","SLC3A2",67.993,47.287,15.4,8,10,8,0.822,0.78,0.828,1.162,1.185,1.211,1.464,6.41E-5,"endoplasmic reticulum\r","GO:1901606 alpha-amino acid catabolic process; GO:0051674 localization of cell; GO:0043090 amino acid import; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0006569 tryptophan catabolic process; GO:0006586 indolalkylamine metabolic process; GO:1901361 organic cyclic compound catabolic process; GO:0044765 single-organism transport; GO:0044106 cellular amine metabolic process; GO:0009072 aromatic amino acid family metabolic process; GO:0014070 response to organic cyclic compound; GO:0098655 cation transmembrane transport; GO:0016049 cell growth; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0043331 response to dsRNA; GO:0048870 cell motility; GO:0005975 carbohydrate metabolic process; GO:0046942 carboxylic acid transport; GO:0006814 sodium ion transport; GO:0046395 carboxylic acid catabolic process; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0015801 aromatic amino acid transport; GO:0050900 leukocyte migration; GO:0042221 response to chemical; GO:0044710 single-organism metabolic process; GO:0009310 amine catabolic process; GO:1901698 response to nitrogen compound; GO:0009063 cellular amino acid catabolic process; GO:0040011 locomotion; GO:0006082 organic acid metabolic process; GO:0043436 oxoacid metabolic process; GO:0098662 inorganic cation transmembrane transport; GO:0015820 leucine transport; GO:0042436 indole-containing compound catabolic process; GO:0016477 cell migration; GO:0035725 sodium ion transmembrane transport; GO:0072511 divalent inorganic cation transport; GO:0034220 ion transmembrane transport; GO:0006725 cellular aromatic compound metabolic process; GO:0030001 metal ion transport; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0006576 cellular biogenic amine metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0006816 calcium ion transport; GO:0006812 cation transport; GO:0006865 amino acid transport; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009987 cellular process; GO:0042430 indole-containing compound metabolic process; GO:0009308 amine metabolic process; GO:0015827 tryptophan transport; GO:0043330 response to exogenous dsRNA; GO:0098660 inorganic ion transmembrane transport; GO:0009074 aromatic amino acid family catabolic process; GO:0044712 single-organism catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044282 small molecule catabolic process; GO:0071702 organic substance transport; GO:0002376 immune system process; GO:0042402 cellular biogenic amine catabolic process; GO:0010033 response to organic substance; GO:1901605 alpha-amino acid metabolic process; GO:0044238 primary metabolic process; GO:0015803 branched-chain amino acid transport; GO:0015849 organic acid transport; GO:0006820 anion transport; GO:0046218 indolalkylamine catabolic process; GO:0055085 transmembrane transport; GO:0015711 organic anion transport; GO:1901565 organonitrogen compound catabolic process; GO:0006811 ion transport; GO:0016054 organic acid catabolic process; GO:0019752 carboxylic acid metabolic process; GO:0006928 movement of cell or subcellular component; GO:0006568 tryptophan metabolic process; GO:0015804 neutral amino acid transport; GO:0051179 localization; GO:0060356 leucine import; GO:0009056 catabolic process; GO:0015672 monovalent inorganic cation transport; GO:0040007 growth; GO:0071705 nitrogen compound transport; GO:0070838 divalent metal ion transport; GO:1901564 organonitrogen compound metabolic process; GO:0046700 heterocycle catabolic process; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0016324 apical plasma membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0048770 pigment granule; GO:0070062 extracellular exosome; GO:0098590 plasma membrane region; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0045177 apical part of cell; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0042470 melanosome; GO:0005829 cytosol; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0009986 cell surface; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0022892 substrate-specific transporter activity; GO:0015077 monovalent inorganic cation transmembrane transporter activity; GO:0005515 protein binding; GO:0015297 antiporter activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0099516 ion antiporter activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0015175 neutral amino acid transmembrane transporter activity; GO:0046873 metal ion transmembrane transporter activity; GO:0003824 catalytic activity; GO:0015368 calcium:cation antiporter activity; GO:0005488 binding; GO:0045296 cadherin binding; GO:0015491 cation:cation antiporter activity; GO:0022890 inorganic cation transmembrane transporter activity; GO:0015081 sodium ion transmembrane transporter activity; GO:0005215 transporter activity; GO:0015291 secondary active transmembrane transporter activity; GO:0022804 active transmembrane transporter activity; GO:0015298 solute:cation antiporter activity; GO:0005342 organic acid transmembrane transporter activity; GO:0003723 RNA binding; GO:0015075 ion transmembrane transporter activity; GO:0003725 double-stranded RNA binding; GO:0050839 cell adhesion molecule binding; GO:0005432 calcium:sodium antiporter activity; GO:0072509 divalent inorganic cation transmembrane transporter activity; GO:0003676 nucleic acid binding; GO:0015085 calcium ion transmembrane transporter activity; GO:0008514 organic anion transmembrane transporter activity; GO:0008324 cation transmembrane transporter activity; GO:0015171 amino acid transmembrane transporter activity; GO:0046943 carboxylic acid transmembrane transporter activity; GO:0022857 transmembrane transporter activity; GO:0008509 anion transmembrane transporter activity; ","K06519","SLC3A2; solute carrier family 3, member 2","hsa04974 Protein digestion and absorption - Homo sapiens (human); hsa04216 Ferroptosis - Homo sapiens (human); hsa04150 mTOR signaling pathway - Homo sapiens (human); ","IPR013780; IPR031984; IPR017853; IPR006047; IPR013781; ","\"Glycosyl hydrolase, all-beta; Solute carrier family 3 member 2, N-terminal domain; Glycoside hydrolase superfamily; Glycosyl hydrolase, family 13, catalytic domain; Glycoside hydrolase, catalytic domain; \"\r"]
["P08236","Beta-glucuronidase OS=Homo sapiens OX=9606 GN=GUSB","GUSB",74.731,11.039,7.1,6,8,6,1.107,1.086,1.11,0.894,0.977,0.933,0.849,3.46E-3,"nucleus\r","GO:0045321 leukocyte activation; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0006026 aminoglycan catabolic process; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0051234 establishment of localization; GO:0030203 glycosaminoglycan metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:1901135 carbohydrate derivative metabolic process; GO:0036230 granulocyte activation; GO:0043170 macromolecule metabolic process; GO:0009987 cellular process; GO:0006022 aminoglycan metabolic process; GO:0030212 hyaluronan metabolic process; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0002443 leukocyte mediated immunity; GO:1903510 mucopolysaccharide metabolic process; GO:0030214 hyaluronan catabolic process; GO:0002446 neutrophil mediated immunity; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:1901136 carbohydrate derivative catabolic process; GO:0002376 immune system process; GO:0005975 carbohydrate metabolic process; GO:0044238 primary metabolic process; GO:0043312 neutrophil degranulation; GO:0002263 cell activation involved in immune response; GO:0002444 myeloid leukocyte mediated immunity; GO:0006027 glycosaminoglycan catabolic process; GO:0006810 transport; GO:0002366 leukocyte activation involved in immune response; GO:1901575 organic substance catabolic process; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:1901565 organonitrogen compound catabolic process; GO:0032940 secretion by cell; GO:0009057 macromolecule catabolic process; GO:0001775 cell activation; GO:0043299 leukocyte degranulation; GO:0051179 localization; GO:0006955 immune response; GO:0009056 catabolic process; GO:0006887 exocytosis; GO:1901564 organonitrogen compound metabolic process; ","GO:0034774 secretory granule lumen; GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0043202 lysosomal lumen; GO:0005576 extracellular region; GO:0042582 azurophil granule; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0003824 catalytic activity; GO:0005102 receptor binding; GO:0005488 binding; GO:0004566 beta-glucuronidase activity; GO:0016798 hydrolase activity, acting on glycosyl bonds; GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds; GO:0019904 protein domain specific binding; GO:0005515 protein binding; GO:0016787 hydrolase activity; ","K01195","uidA; beta-glucuronidase [EC:3.2.1.31]","hsa04142 Lysosome - Homo sapiens (human); hsa00983 Drug metabolism - other enzymes - Homo sapiens (human); hsa00040 Pentose and glucuronate interconversions - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00531 Glycosaminoglycan degradation - Homo sapiens (human); hsa00860 Porphyrin and chlorophyll metabolism - Homo sapiens (human); ","IPR006104; IPR006102; IPR017853; IPR008979; IPR013781; IPR006103; IPR013812; ","\"Glycosyl hydrolases family 2, sugar binding domain; Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich; Glycoside hydrolase superfamily; Galactose-binding domain-like; Glycoside hydrolase, catalytic domain; Glycoside hydrolase family 2, catalytic domain; Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain; \"\r"]
["P08237","ATP-dependent 6-phosphofructokinase, muscle type OS=Homo sapiens OX=9606 GN=PFKM","PFKM",85.182,170.25,27.4,19,27,16,1.038,1.078,1.046,0.977,0.946,0.974,0.916,0.0048,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0009116 nucleoside metabolic process; GO:0006165 nucleoside diphosphate phosphorylation; GO:0019362 pyridine nucleotide metabolic process; GO:0006096 glycolytic process; GO:0050796 regulation of insulin secretion; GO:0042593 glucose homeostasis; GO:0006002 fructose 6-phosphate metabolic process; GO:0009185 ribonucleoside diphosphate metabolic process; GO:0002793 positive regulation of peptide secretion; GO:0044237 cellular metabolic process; GO:0044264 cellular polysaccharide metabolic process; GO:0006006 glucose metabolic process; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0044262 cellular carbohydrate metabolic process; GO:0032879 regulation of localization; GO:0065003 macromolecular complex assembly; GO:0032787 monocarboxylic acid metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0043170 macromolecule metabolic process; GO:0009179 purine ribonucleoside diphosphate metabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0061620 glycolytic process through glucose-6-phosphate; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0006732 coenzyme metabolic process; GO:0005975 carbohydrate metabolic process; GO:0061718 glucose catabolic process to pyruvate; GO:1901575 organic substance catabolic process; GO:0046883 regulation of hormone secretion; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0019674 NAD metabolic process; GO:0044710 single-organism metabolic process; GO:0046716 muscle cell cellular homeostasis; GO:0050714 positive regulation of protein secretion; GO:0044260 cellular macromolecule metabolic process; GO:0010817 regulation of hormone levels; GO:0051223 regulation of protein transport; GO:0009126 purine nucleoside monophosphate metabolic process; GO:0043436 oxoacid metabolic process; GO:0051047 positive regulation of secretion; GO:0050794 regulation of cellular process; GO:0016310 phosphorylation; GO:0046496 nicotinamide nucleotide metabolic process; GO:0044275 cellular carbohydrate catabolic process; GO:0009259 ribonucleotide metabolic process; GO:0044042 glucan metabolic process; GO:0006735 NADH regeneration; GO:0060249 anatomical structure homeostasis; GO:0090277 positive regulation of peptide hormone secretion; GO:0051259 protein oligomerization; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0046835 carbohydrate phosphorylation; GO:0044248 cellular catabolic process; GO:0033500 carbohydrate homeostasis; GO:1901135 carbohydrate derivative metabolic process; GO:0032880 regulation of protein localization; GO:0009119 ribonucleoside metabolic process; GO:0006461 protein complex assembly; GO:0048878 chemical homeostasis; GO:0090087 regulation of peptide transport; GO:0005977 glycogen metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0006163 purine nucleotide metabolic process; GO:0061622 glycolytic process through glucose-1-phosphate; GO:1904951 positive regulation of establishment of protein localization; GO:0006793 phosphorus metabolic process; GO:0046887 positive regulation of hormone secretion; GO:0019637 organophosphate metabolic process; GO:0019320 hexose catabolic process; GO:0019318 hexose metabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0006757 ATP generation from ADP; GO:0046365 monosaccharide catabolic process; GO:0042278 purine nucleoside metabolic process; GO:0046031 ADP metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0051046 regulation of secretion; GO:0046939 nucleotide phosphorylation; GO:0009135 purine nucleoside diphosphate metabolic process; GO:0072524 pyridine-containing compound metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0061615 glycolytic process through fructose-6-phosphate; GO:0005980 glycogen catabolic process; GO:0010646 regulation of cell communication; GO:0022607 cellular component assembly; GO:0006753 nucleoside phosphate metabolic process; GO:0071822 protein complex subunit organization; GO:0009251 glucan catabolic process; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0006073 cellular glucan metabolic process; GO:0055114 oxidation-reduction process; GO:0019725 cellular homeostasis; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:1903530 regulation of secretion by cell; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0051050 positive regulation of transport; GO:0051186 cofactor metabolic process; GO:0016052 carbohydrate catabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0050789 regulation of biological process; GO:1903532 positive regulation of secretion by cell; GO:0015980 energy derivation by oxidation of organic compounds; GO:1901657 glycosyl compound metabolic process; GO:0006082 organic acid metabolic process; GO:0070271 protein complex biogenesis; GO:0051222 positive regulation of protein transport; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0006734 NADH metabolic process; GO:0006112 energy reserve metabolic process; GO:0070201 regulation of establishment of protein localization; GO:0071704 organic substance metabolic process; GO:0061621 canonical glycolysis; GO:0042592 homeostatic process; GO:0002791 regulation of peptide secretion; GO:0006090 pyruvate metabolic process; GO:0023056 positive regulation of signaling; GO:0005976 polysaccharide metabolic process; GO:0005996 monosaccharide metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0010647 positive regulation of cell communication; GO:0050708 regulation of protein secretion; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0009132 nucleoside diphosphate metabolic process; GO:0046034 ATP metabolic process; GO:0032024 positive regulation of insulin secretion; GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate; GO:0044724 single-organism carbohydrate catabolic process; GO:0051049 regulation of transport; GO:0044712 single-organism catabolic process; GO:0044247 cellular polysaccharide catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044282 small molecule catabolic process; GO:0000272 polysaccharide catabolic process; GO:0048518 positive regulation of biological process; GO:0043933 macromolecular complex subunit organization; GO:0046128 purine ribonucleoside metabolic process; GO:0006007 glucose catabolic process; GO:0009057 macromolecule catabolic process; GO:0090276 regulation of peptide hormone secretion; GO:0019752 carboxylic acid metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0009056 catabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0061695 transferase complex, transferring phosphorus-containing groups; GO:0016324 apical plasma membrane; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0036126 sperm flagellum; GO:0097729 9+2 motile cilium; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:1902494 catalytic complex; GO:0098590 plasma membrane region; GO:0044441 ciliary part; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0044445 cytosolic part; GO:0043227 membrane-bounded organelle; GO:0097228 sperm principal piece; GO:0045177 apical part of cell; GO:0005929 cilium; GO:0042995 cell projection; GO:0005945 6-phosphofructokinase complex; GO:1990234 transferase complex; GO:0005829 cytosol; GO:0031514 motile cilium; GO:0044463 cell projection part; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0097223 sperm part; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0003872 6-phosphofructokinase activity; GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:0048029 monosaccharide binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016301 kinase activity; GO:0042802 identical protein binding; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0070061 fructose binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0008022 protein C-terminus binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0019900 kinase binding; GO:0032549 ribonucleoside binding; GO:0019200 carbohydrate kinase activity; GO:0097367 carbohydrate derivative binding; GO:0042803 protein homodimerization activity; GO:0008443 phosphofructokinase activity; GO:0046872 metal ion binding; GO:0030246 carbohydrate binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019899 enzyme binding; GO:0036094 small molecule binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K00850","pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]","hsa00051 Fructose and mannose metabolism - Homo sapiens (human); hsa04066 HIF-1 signaling pathway - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa04922 Glucagon signaling pathway - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); hsa05230 Central carbon metabolism in cancer - Homo sapiens (human); hsa04152 AMPK signaling pathway - Homo sapiens (human); hsa03018 RNA degradation - Homo sapiens (human); hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human); hsa00030 Pentose phosphate pathway - Homo sapiens (human); hsa00052 Galactose metabolism - Homo sapiens (human); hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human); hsa01230 Biosynthesis of amino acids - Homo sapiens (human); ","IPR000023; ","Phosphofructokinase domain; \r"]
["P08238","Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1","HSP90AB1",83.263,255.48,48.6,36,98,17,0.92,0.892,0.896,1.109,1.116,1.126,1.237,3.81e-05,"cytoplasm\r",{"$cut":{"chars":17287,"head":"GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0010941 regulation of cell death; GO:0022414 reproductive process; GO:0043523 regulation of neuron apoptotic process; GO:0009891 positive regulation of biosynthetic process; GO:0031347 regulation of defense response; GO:0044237 cellular metabolic process; GO:0010564 regulation of cell cycle process; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0008152 metabolic process; GO:0065003 macromolecular complex assembly; GO:0032535 regulation of cellular component size; GO:0044093 positive regulation of molecular function; GO:0051099 positive regulation of binding; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0060359 response to ammonium ion; GO:0051054 positive regulation of DNA metabolic process; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0090287 regulation of cellular response to growth factor stimulus; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0010243 response to organonitrogen compound; GO:0080135 regulation of cellular response to stress; GO:0061136 regulation of proteasomal protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0035304 regulation of protein dephosphorylation; GO:0044260 cellular macromolecule metabolic process; GO:1901698 response to nitrogen compound; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0051223 regulation of protein transport; GO:0060548 negative regulation of cell death; GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0042307 positive regulation of protein import into nucleus; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0000003 reproduction; GO:0044707 single-multicellular organism process; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:1903051 negative regulation of proteolysis involved in cellular protein catabolic process; GO:0006259 DNA metabolic process; GO:1901700 response to oxygen-containing compound; GO:0033158 regulation of protein import into nucleus, translocation; GO:0048519 negative regulation of biological process; GO:1901799 negative regulation of proteasomal protein catabolic process; GO:0042493 response to drug; GO:0046483 heterocycle metabolic process; GO:0043524 negative regulation of neuron apoptotic process; GO:0009410 response to xenobiotic stimulus; GO:0006139 nucleobase-containing compound metabolic process; GO:0051345 positive regulation of hydrolase activity; GO:0009889 regulation of biosynthetic process; GO:0042176 regulation of protein catabolic process; GO:0038093 Fc receptor signaling pathway; GO:0061458 reproductive system development; GO:0050778 positive regulation of immune response; GO:1901215 negative regulation of neuron death; GO:0006986 response to unfolded protein; GO:0045861 negative regulation of proteolysis; GO:0006950 response to stress; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0002263 cell activation involved in immune response; GO:1901576 organic substance biosynthetic process; GO:2000278 regulation of DNA biosynthetic process; GO:1900182 positive regulation of protein localization to nucleus; GO:0045055 regulated exocytosis; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0031647 regulation of protein stability; GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis; GO:0006955 immune response; GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway; GO:0050821 protein stabilization; GO:1903827 regulation of cellular protein localization; GO:0023051 regulation of signaling; GO:2000008 regulation of protein localization to cell surface; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0010833 telomere"}},"GO:0016020 membrane; GO:0098862 cluster of actin-based cell projections; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0097524 sperm plasma membrane; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0005765 lysosomal membrane; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0005654 nucleoplasm; GO:0098590 plasma membrane region; GO:0005622 intracellular; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:0043227 membrane-bounded organelle; GO:0045177 apical part of cell; GO:1990913 sperm head plasma membrane; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0042995 cell projection; GO:0031526 brush border membrane; GO:1990917 ooplasm; GO:0016234 inclusion body; GO:0043235 receptor complex; GO:0031981 nuclear lumen; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0097223 sperm part; GO:0043230 extracellular organelle; GO:0034751 aryl hydrocarbon receptor complex; GO:0034774 secretory granule lumen; GO:0016323 basolateral plasma membrane; GO:0016324 apical plasma membrane; GO:0005903 brush border; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0048770 pigment granule; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0061827 sperm head; GO:0098588 bounding membrane of organelle; GO:0042470 melanosome; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0044459 plasma membrane part; GO:0005774 vacuolar membrane; GO:0031253 cell projection membrane; GO:0009986 cell surface; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0001884 pyrimidine nucleoside binding; GO:0097159 organic cyclic compound binding; GO:0042826 histone deacetylase binding; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0019103 pyrimidine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0032557 pyrimidine ribonucleotide binding; GO:0005524 ATP binding; GO:0003725 double-stranded RNA binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0008144 drug binding; GO:0017098 sulfonylurea receptor binding; GO:0030234 enzyme regulator activity; GO:0003676 nucleic acid binding; GO:0032561 guanyl ribonucleotide binding; GO:0051082 unfolded protein binding; GO:0030235 nitric-oxide synthase regulator activity; GO:1901265 nucleoside phosphate binding; GO:0005102 receptor binding; GO:0070182 DNA polymerase binding; GO:0019901 protein kinase binding; GO:0046983 protein dimerization activity; GO:0032554 purine deoxyribonucleotide binding; GO:0005515 protein binding; GO:0019207 kinase regulator activity; GO:0098772 molecular function regulator; GO:0003823 antigen binding; GO:1901363 heterocyclic compound binding; GO:0002134 UTP binding; GO:0023023 MHC protein complex binding; GO:0023026 MHC class II protein complex binding; GO:0045296 cadherin binding; GO:0030911 TPR domain binding; GO:0032558 adenyl deoxyribonucleotide binding; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0003723 RNA binding; GO:0031072 heat shock protein binding; GO:0043167 ion binding; GO:0044877 macromolecular complex binding; GO:0019887 protein kinase regulator activity; GO:0019900 kinase binding; GO:0032552 deoxyribonucleotide binding; GO:0032564 dATP binding; GO:0032549 ribonucleoside binding; GO:0050839 cell adhesion molecule binding; GO:0097367 carbohydrate derivative binding; GO:0002135 CTP binding; GO:0032551 pyrimidine ribonucleoside binding; GO:1990226 histone methyltransferase binding; GO:0044325 ion channel binding; GO:0032555 purine ribonucleotide binding; GO:0019904 protein domain specific binding; GO:0001883 purine nucleoside binding; GO:0001948 glycoprotein binding; GO:0019899 enzyme binding; GO:0036094 small molecule binding; GO:0032403 protein complex binding; ","K04079","HSP90A; molecular chaperone HtpG","hsa05200 Pathways in cancer - Homo sapiens (human); hsa04657 IL-17 signaling pathway - Homo sapiens (human); hsa04659 Th17 cell differentiation - Homo sapiens (human); hsa04217 Necroptosis - Homo sapiens (human); hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human); hsa04612 Antigen processing and presentation - Homo sapiens (human); hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); hsa05215 Prostate cancer - Homo sapiens (human); hsa04914 Progesterone-mediated oocyte maturation - Homo sapiens (human); hsa04915 Estrogen signaling pathway - Homo sapiens (human); ","IPR020575; IPR020568; IPR003594; ","\"Heat shock protein Hsp90, N-terminal; Ribosomal protein S5 domain 2-type fold; Histidine kinase-like ATPase, C-terminal domain; \"\r"]
["P08240","Signal recognition particle receptor subunit alpha OS=Homo sapiens OX=9606 GN=SRPRA","SRPRA",69.81,34.049,14.7,9,12,9,0.956,0.939,0.951,1.052,1.086,1.046,1.119,0.000943,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0046907 intracellular transport; GO:0033554 cellular response to stress; GO:0072594 establishment of protein localization to organelle; GO:0034976 response to endoplasmic reticulum stress; GO:0035967 cellular response to topologically incorrect protein; GO:0071310 cellular response to organic substance; GO:0044699 single-organism process; GO:0036498 IRE1-mediated unfolded protein response; GO:0006613 cotranslational protein targeting to membrane; GO:0050896 response to stimulus; GO:0015031 protein transport; GO:0030968 endoplasmic reticulum unfolded protein response; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0035966 response to topologically incorrect protein; GO:0007154 cell communication; GO:0070972 protein localization to endoplasmic reticulum; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0006886 intracellular protein transport; GO:0033365 protein localization to organelle; GO:0034613 cellular protein localization; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0090150 establishment of protein localization to membrane; GO:0009987 cellular process; GO:0070887 cellular response to chemical stimulus; GO:0006986 response to unfolded protein; GO:0051716 cellular response to stimulus; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0034620 cellular response to unfolded protein; GO:0006950 response to stress; GO:0072657 protein localization to membrane; GO:0045047 protein targeting to ER; GO:0071702 organic substance transport; GO:0010033 response to organic substance; GO:0023052 signaling; GO:0051641 cellular localization; GO:0006810 transport; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0051179 localization; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0030867 rough endoplasmic reticulum membrane; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005785 signal recognition particle receptor complex; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0005791 rough endoplasmic reticulum; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044432 endoplasmic reticulum part; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0003924 GTPase activity; GO:0043168 anion binding; GO:0019001 guanyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003723 RNA binding; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0005047 signal recognition particle binding; GO:0003676 nucleic acid binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0032561 guanyl ribonucleotide binding; GO:0043021 ribonucleoprotein complex binding; GO:0036094 small molecule binding; ","K13431","SRPR; signal recognition particle receptor subunit alpha","hsa03060 Protein export - Homo sapiens (human); ","IPR003593; IPR007222; IPR013822; IPR027417; IPR000897; IPR011012; ","\"AAA+ ATPase domain; Signal recognition particle receptor, alpha subunit, N-terminal; Signal recognition particle, SRP54 subunit, helical bundle; P-loop containing nucleoside triphosphate hydrolase; Signal recognition particle, SRP54 subunit, GTPase domain; Longin-like domain; \"\r"]
["P08246","Neutrophil elastase OS=Homo sapiens OX=9606 GN=ELANE","ELANE",28.518,5.3244,9.4,3,5,3,0.535,0.569,0.614,1.384,1.417,1.432,2.464,2.27E-5,"extracellular\r","GO:0009891 positive regulation of biosynthetic process; GO:0098542 defense response to other organism; GO:0031347 regulation of defense response; GO:0001878 response to yeast; GO:0009607 response to biotic stimulus; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0008152 metabolic process; GO:0051883 killing of cells in other organism involved in symbiotic interaction; GO:0044093 positive regulation of molecular function; GO:0055065 metal ion homeostasis; GO:0001906 cell killing; GO:0042325 regulation of phosphorylation; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0048870 cell motility; GO:0006874 cellular calcium ion homeostasis; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0030163 protein catabolic process; GO:0002526 acute inflammatory response; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0002687 positive regulation of leukocyte migration; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0032677 regulation of interleukin-8 production; GO:0042036 negative regulation of cytokine biosynthetic process; GO:0001819 positive regulation of cytokine production; GO:0050728 negative regulation of inflammatory response; GO:1901700 response to oxygen-containing compound; GO:0048519 negative regulation of biological process; GO:0051817 modification of morphology or physiology of other organism involved in symbiotic interaction; GO:0044146 negative regulation of growth of symbiont involved in interaction with host; GO:0045892 negative regulation of transcription, DNA-templated; GO:0031640 killing of cells of other organism; GO:2000145 regulation of cell motility; GO:0009889 regulation of biosynthetic process; GO:0043062 extracellular structure organization; GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:0051702 interaction with symbiont; GO:0032717 negative regulation of interleukin-8 production; GO:0002438 acute inflammatory response to antigenic stimulus; GO:0050778 positive regulation of immune response; GO:0048878 chemical homeostasis; GO:0045073 regulation of chemokine biosynthetic process; GO:0009416 response to light stimulus; GO:0045785 positive regulation of cell adhesion; GO:0006950 response to stress; GO:0051270 regulation of cellular component movement; GO:0032496 response to lipopolysaccharide; GO:0002376 immune system process; GO:0032101 regulation of response to external stimulus; GO:0010033 response to organic substance; GO:1903238 positive regulation of leukocyte tethering or rolling; GO:0002263 cell activation involved in immune response; GO:1903039 positive regulation of leukocyte cell-cell adhesion; GO:0045055 regulated exocytosis; GO:0009890 negative regulation of biosynthetic process; GO:0031325 positive regulation of cellular metabolic process; GO:0006955 immune response; GO:0008284 positive regulation of cell proliferation; GO:0051674 localization of cell; GO:0051852 disruption by host of symbiont cells; GO:0040017 positive regulation of locomotion; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0051253 negative regulation of RNA metabolic process; GO:0040013 negative regulation of locomotion; GO:2001141 regulation of RNA biosynthetic process; GO:0009893 positive regulation of metabolic process; GO:0032642 regulation of chemokine production; GO:0030198 extracellular matrix organization; GO:0033674 positive regulation of kinase activity; GO:0042035 regulation of cytokine biosynthetic process; GO:0045926 negative regulation of growth; GO:0045937 positive regulation of phosphate metabolic process; GO:0031326 regulation of cellular biosynthetic process; GO:0002237 response to molecule of bacterial origin; GO:0098771 inorganic ion homeostasis; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0032940 secretion by cell; GO:0032682 negative regulation of chemokine production; GO:1902679 negative regulation of RNA biosynthetic process; GO:0006954 inflammatory response; GO:0065009 regulation of molecular function; GO:0006952 defense response; GO:0045415 negative regulation of interleukin-8 biosynthetic process; GO:0043549 regulation of kinase activity; GO:0051851 modification by host of symbiont morphology or physiology; GO:0016477 cell migration; GO:0016043 cellular component organization; GO:0040008 regulation of growth; GO:0060255 regulation of macromolecule metabolic process; GO:0051707 response to other organism; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0033993 response to lipid; GO:0032757 positive regulation of interleukin-8 production; GO:0043408 regulation of MAPK cascade; GO:0055080 cation homeostasis; GO:0023056 positive regulation of signaling; GO:0010647 positive regulation of cell communication; GO:0031348 negative regulation of defense response; GO:1903236 regulation of leukocyte tethering or rolling; GO:0070947 neutrophil mediated killing of fungus; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0042742 defense response to bacterium; GO:0001932 regulation of protein phosphorylation; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0045414 regulation of interleukin-8 biosynthetic process; GO:0001934 positive regulation of protein phosphorylation; GO:0050920 regulation of chemotaxis; GO:0022407 regulation of cell-cell adhesion; GO:0043085 positive regulation of catalytic activity; GO:0043901 negative regulation of multi-organism process; GO:0002366 leukocyte activation involved in immune response; GO:0050832 defense response to fungus; GO:0042119 neutrophil activation; GO:0002684 positive regulation of immune system process; GO:0050727 regulation of inflammatory response; GO:0051248 negative regulation of protein metabolic process; GO:0001817 regulation of cytokine production; GO:0031327 negative regulation of cellular biosynthetic process; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065008 regulation of biological quality; GO:0030335 positive regulation of cell migration; GO:0045321 leukocyte activation; GO:0032270 positive regulation of cellular protein metabolic process; GO:0042108 positive regulation of cytokine biosynthetic process; GO:0009605 response to external stimulus; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0032102 negative regulation of response to external stimulus; GO:0010562 positive regulation of phosphorus metabolic process; GO:0042327 positive regulation of phosphorylation; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0051347 positive regulation of transferase activity; GO:0044419 interspecies interaction between organisms; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0009620 response to fungus; GO:0002443 leukocyte mediated immunity; GO:0051174 regulation of phosphorus metabolic process; GO:0019730 antimicrobial humoral response; GO:0000122 negative regulation of transcription from RNA polymerase II promoter; GO:0051272 positive regulation of cellular component movement; GO:0031323 regulation of cellular metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0001909 leukocyte mediated cytotoxicity; GO:0050900 leukocyte migration; GO:0050790 regulation of catalytic activity; GO:0010604 positive regulation of macromolecule metabolic process; GO:0002682 regulation of immune system process; GO:0002685 regulation of leukocyte migration; GO:0045416 positive regulation of interleukin-8 biosynthetic process; GO:0050794 regulation of cellular process; GO:0002283 neutrophil activation involved in immune response; GO:0042127 regulation of cell proliferation; GO:0044144 modulation of growth of symbiont involved in interaction with host; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:2000147 positive regulation of cell motility; GO:0071902 positive regulation of protein serine/threonine kinase activity; GO:0051239 regulation of multicellular organismal process; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0009966 regulation of signal transduction; GO:0009617 response to bacterium; GO:0051818 disruption of cells of other organism involved in symbiotic interaction; GO:1902531 regulation of intracellular signal transduction; GO:0016192 vesicle-mediated transport; GO:0043900 regulation of multi-organism process; GO:0002523 leukocyte migration involved in inflammatory response; GO:0030334 regulation of cell migration; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0030155 regulation of cell adhesion; GO:0002691 regulation of cellular extravasation; GO:0051247 positive regulation of protein metabolic process; GO:0043406 positive regulation of MAP kinase activity; GO:0006873 cellular ion homeostasis; GO:0044364 disruption of cells of other organism; GO:0006928 movement of cell or subcellular component; GO:0001775 cell activation; GO:0048661 positive regulation of smooth muscle cell proliferation; GO:0031328 positive regulation of cellular biosynthetic process; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:0006887 exocytosis; GO:0045079 negative regulation of chemokine biosynthetic process; GO:0072503 cellular divalent inorganic cation homeostasis; GO:0050922 negative regulation of chemotaxis; GO:1902533 positive regulation of intracellular signal transduction; GO:0051241 negative regulation of multicellular organismal process; GO:0035821 modification of morphology or physiology of other organism; GO:0001818 negative regulation of cytokine production; GO:0051234 establishment of localization; GO:0006909 phagocytosis; GO:0044126 regulation of growth of symbiont in host; GO:0010646 regulation of cell communication; GO:0022617 extracellular matrix disassembly; GO:0009314 response to radiation; GO:0002437 inflammatory response to antigenic stimulus; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0002274 myeloid leukocyte activation; GO:0010468 regulation of gene expression; GO:0050801 ion homeostasis; GO:0055074 calcium ion homeostasis; GO:0002446 neutrophil mediated immunity; GO:0048522 positive regulation of cellular process; GO:0019725 cellular homeostasis; GO:0002693 positive regulation of cellular extravasation; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0019222 regulation of metabolic process; GO:0040011 locomotion; GO:0043299 leukocyte degranulation; GO:0019220 regulation of phosphate metabolic process; GO:0072507 divalent inorganic cation homeostasis; GO:0045859 regulation of protein kinase activity; GO:1904994 regulation of leukocyte adhesion to vascular endothelial cell; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0002252 immune effector process; GO:0048660 regulation of smooth muscle cell proliferation; GO:0043405 regulation of MAP kinase activity; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0030003 cellular cation homeostasis; GO:0006959 humoral immune response; GO:0031324 negative regulation of cellular metabolic process; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0055082 cellular chemical homeostasis; GO:0070942 neutrophil mediated cytotoxicity; GO:0006508 proteolysis; GO:0044130 negative regulation of growth of symbiont in host; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0022409 positive regulation of cell-cell adhesion; GO:0051873 killing by host of symbiont cells; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0031401 positive regulation of protein modification process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0006897 endocytosis; GO:0043312 neutrophil degranulation; GO:0045860 positive regulation of protein kinase activity; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0070943 neutrophil mediated killing of symbiont cell; GO:0009411 response to UV; GO:0051246 regulation of protein metabolic process; GO:0009057 macromolecule catabolic process; GO:0022411 cellular component disassembly; GO:0006875 cellular metal ion homeostasis; GO:0009967 positive regulation of signal transduction; GO:0040012 regulation of locomotion; GO:0043410 positive regulation of MAPK cascade; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0017053 transcriptional repressor complex; GO:0044424 intracellular part; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0042582 azurophil granule; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0035580 specific granule lumen; GO:0005766 primary lysosome; GO:0042581 specific granule; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0009986 cell surface; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0003714 transcription corepressor activity; GO:0008233 peptidase activity; GO:0043167 ion binding; GO:0008236 serine-type peptidase activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0003712 transcription cofactor activity; GO:0008201 heparin binding; GO:1901681 sulfur compound binding; GO:0002020 protease binding; GO:0004252 serine-type endopeptidase activity; GO:0004175 endopeptidase activity; GO:0019955 cytokine binding; GO:0097367 carbohydrate derivative binding; GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding; GO:0001104 RNA polymerase II transcription cofactor activity; GO:0003824 catalytic activity; GO:0017171 serine hydrolase activity; GO:0005488 binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0001106 RNA polymerase II transcription corepressor activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0043168 anion binding; GO:0005539 glycosaminoglycan binding; GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding; GO:0000988 transcription factor activity, protein binding; GO:0019899 enzyme binding; ","K01327","ELANE; leukocyte elastase [EC:3.4.21.37]","hsa05322 Systemic lupus erythematosus - Homo sapiens (human); hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human); ","IPR009003; IPR001254; ","\"Peptidase S1, PA clan; Serine proteases, trypsin domain; \"\r"]
["P08253","72 kDa type IV collagenase OS=Homo sapiens OX=9606 GN=MMP2","MMP2",73.881,85.474,25.5,14,22,14,1.132,1.142,1.133,0.886,0.892,0.869,0.777,3.5e-06,"extracellular\r","GO:0044700 single organism signaling; GO:0021700 developmental maturation; GO:0007166 cell surface receptor signaling pathway; GO:0022414 reproductive process; GO:0007566 embryo implantation; GO:0031347 regulation of defense response; GO:0044237 cellular metabolic process; GO:0007492 endoderm development; GO:0001525 angiogenesis; GO:0008152 metabolic process; GO:0060343 trabecula formation; GO:0044706 multi-multicellular organism process; GO:0044702 single organism reproductive process; GO:0009719 response to endogenous stimulus; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0009790 embryo development; GO:0044259 multicellular organismal macromolecule metabolic process; GO:0048598 embryonic morphogenesis; GO:0030574 collagen catabolic process; GO:0051716 cellular response to stimulus; GO:0001503 ossification; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0060346 bone trabecula formation; GO:0061383 trabecula morphogenesis; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0010243 response to organonitrogen compound; GO:0048513 animal organ development; GO:0044710 single-organism metabolic process; GO:0071230 cellular response to amino acid stimulus; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0044260 cellular macromolecule metabolic process; GO:0009887 animal organ morphogenesis; GO:0002682 regulation of immune system process; GO:1904705 regulation of vascular smooth muscle cell proliferation; GO:0010171 body morphogenesis; GO:0060325 face morphogenesis; GO:0050794 regulation of cellular process; GO:0000003 reproduction; GO:0072359 circulatory system development; GO:0044707 single-multicellular organism process; GO:0042127 regulation of cell proliferation; GO:0061430 bone trabecula morphogenesis; GO:0009628 response to abiotic stimulus; GO:1904707 positive regulation of vascular smooth muscle cell proliferation; GO:1901700 response to oxygen-containing compound; GO:0044267 cellular protein metabolic process; GO:0080134 regulation of response to stress; GO:0007565 female pregnancy; GO:0009653 anatomical structure morphogenesis; GO:0031349 positive regulation of defense response; GO:0071229 cellular response to acid chemical; GO:0043062 extracellular structure organization; GO:0070482 response to oxygen levels; GO:0007275 multicellular organism development; GO:0050778 positive regulation of immune response; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0006950 response to stress; GO:0048731 system development; GO:0072358 cardiovascular system development; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0048705 skeletal system morphogenesis; GO:0001955 blood vessel maturation; GO:0032963 collagen metabolic process; GO:0048661 positive regulation of smooth muscle cell proliferation; GO:0036293 response to decreased oxygen levels; GO:0048584 positive regulation of response to stimulus; GO:0008284 positive regulation of cell proliferation; GO:0001101 response to acid chemical; GO:0001568 blood vessel development; GO:0048869 cellular developmental process; GO:0044236 multicellular organism metabolic process; GO:0044699 single-organism process; GO:0036072 direct ossification; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0045088 regulation of innate immune response; GO:0022617 extracellular matrix disassembly; GO:0060322 head development; GO:0048514 blood vessel morphogenesis; GO:0030198 extracellular matrix organization; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0043200 response to amino acid; GO:0009888 tissue development; GO:0001704 formation of primary germ layer; GO:0048522 positive regulation of cellular process; GO:0001944 vasculature development; GO:0023052 signaling; GO:0071417 cellular response to organonitrogen compound; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0001957 intramembranous ossification; GO:1901699 cellular response to nitrogen compound; GO:0048856 anatomical structure development; GO:0001501 skeletal system development; GO:0071695 anatomical structure maturation; GO:0016043 cellular component organization; GO:0060324 face development; GO:0048660 regulation of smooth muscle cell proliferation; GO:0071310 cellular response to organic substance; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0007369 gastrulation; GO:0044243 multicellular organismal catabolic process; GO:0030154 cell differentiation; GO:0048013 ephrin receptor signaling pathway; GO:0060323 head morphogenesis; GO:0001666 response to hypoxia; GO:0006508 proteolysis; GO:0009987 cellular process; GO:0045089 positive regulation of innate immune response; GO:0001706 endoderm formation; GO:0035987 endodermal cell differentiation; GO:0044712 single-organism catabolic process; GO:0048518 positive regulation of biological process; GO:1901701 cellular response to oxygen-containing compound; GO:0044767 single-organism developmental process; GO:0071495 cellular response to endogenous stimulus; GO:0044703 multi-organism reproductive process; GO:0002684 positive regulation of immune system process; GO:0022411 cellular component disassembly; GO:0009056 catabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0071944 cell periphery; GO:0030016 myofibril; GO:0005737 cytoplasm; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0099081 supramolecular polymer; GO:0005886 plasma membrane; GO:0043228 non-membrane-bounded organelle; GO:0031012 extracellular matrix; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:0043292 contractile fiber; GO:0030017 sarcomere; GO:0005578 proteinaceous extracellular matrix; GO:0044449 contractile fiber part; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0004222 metalloendopeptidase activity; GO:0008233 peptidase activity; GO:0008236 serine-type peptidase activity; GO:0043167 ion binding; GO:0008237 metallopeptidase activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0008270 zinc ion binding; GO:0004175 endopeptidase activity; GO:0004252 serine-type endopeptidase activity; GO:0046914 transition metal ion binding; GO:0017171 serine hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0046872 metal ion binding; GO:0043169 cation binding; ","K01398","MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]","hsa05200 Pathways in cancer - Homo sapiens (human); hsa05219 Bladder cancer - Homo sapiens (human); hsa04912 GnRH signaling pathway - Homo sapiens (human); hsa04933 AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa04670 Leukocyte transendothelial migration - Homo sapiens (human); hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human); hsa01522 Endocrine resistance - Homo sapiens (human); hsa04926 Relaxin signaling pathway - Homo sapiens (human); hsa04915 Estrogen signaling pathway - Homo sapiens (human); ","IPR001818; IPR002477; IPR024079; IPR000585; IPR013806; IPR033739; IPR006026; IPR000562; ","\"Peptidase M10, metallopeptidase; Peptidoglycan binding-like; Metallopeptidase, catalytic domain; Hemopexin-like domain; Kringle-like fold; Peptidase M10A, catalytic domain; Peptidase, metallopeptidase; Fibronectin, type II, collagen-binding; \"\r"]
["P08294","Extracellular superoxide dismutase [Cu-Zn] OS=Homo sapiens OX=9606 GN=SOD3","SOD3",25.851,113.34,42.9,8,25,8,1.082,1.099,1.054,0.883,0.95,0.937,0.856,0.00368,"extracellular\r","GO:0006801 superoxide metabolic process; GO:0033554 cellular response to stress; GO:0000303 response to superoxide; GO:0009628 response to abiotic stimulus; GO:1901700 response to oxygen-containing compound; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0019430 removal of superoxide radicals; GO:0008152 metabolic process; GO:1990748 cellular detoxification; GO:0072593 reactive oxygen species metabolic process; GO:0001666 response to hypoxia; GO:0070482 response to oxygen levels; GO:0006979 response to oxidative stress; GO:0098869 cellular oxidant detoxification; GO:0010035 response to inorganic substance; GO:0034599 cellular response to oxidative stress; GO:0009987 cellular process; GO:0070887 cellular response to chemical stimulus; GO:0051716 cellular response to stimulus; GO:0034614 cellular response to reactive oxygen species; GO:0006950 response to stress; GO:0071450 cellular response to oxygen radical; GO:0071451 cellular response to superoxide; GO:0055114 oxidation-reduction process; GO:0000302 response to reactive oxygen species; GO:0009636 response to toxic substance; GO:0010038 response to metal ion; GO:0042221 response to chemical; GO:1901701 cellular response to oxygen-containing compound; GO:0044710 single-organism metabolic process; GO:0046688 response to copper ion; GO:0000305 response to oxygen radical; GO:0036293 response to decreased oxygen levels; GO:0098754 detoxification; ","GO:0043229 intracellular organelle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0005796 Golgi lumen; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0031012 extracellular matrix; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0005794 Golgi apparatus; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0004784 superoxide dismutase activity; GO:0016721 oxidoreductase activity, acting on superoxide radicals as acceptor; GO:0043167 ion binding; GO:0016209 antioxidant activity; GO:0005515 protein binding; GO:0005507 copper ion binding; GO:0008201 heparin binding; GO:0008270 zinc ion binding; GO:1901681 sulfur compound binding; GO:0016491 oxidoreductase activity; GO:0097367 carbohydrate derivative binding; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0043168 anion binding; GO:0005539 glycosaminoglycan binding; ","K16627",null,null,"IPR001424; ","\"Superoxide dismutase, copper/zinc binding domain; \"\r"]
["P08311","Cathepsin G OS=Homo sapiens OX=9606 GN=CTSG","CTSG",28.837,80.895,38.4,9,22,9,1.217,1.211,1.208,0.755,0.832,0.8,0.656,0.00448,"extracellular\r","GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0006518 peptide metabolic process; GO:0070946 neutrophil mediated killing of gram-positive bacterium; GO:0098542 defense response to other organism; GO:0016486 peptide hormone processing; GO:0060177 regulation of angiotensin metabolic process; GO:0044237 cellular metabolic process; GO:0009607 response to biotic stimulus; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0051883 killing of cells in other organism involved in symbiotic interaction; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0001906 cell killing; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0003044 regulation of systemic arterial blood pressure mediated by a chemical signal; GO:0051716 cellular response to stimulus; GO:0009620 response to fungus; GO:0002443 leukocyte mediated immunity; GO:0001990 regulation of systemic arterial blood pressure by hormone; GO:0080090 regulation of primary metabolic process; GO:0019730 antimicrobial humoral response; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032501 multicellular organismal process; GO:0071396 cellular response to lipid; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0001909 leukocyte mediated cytotoxicity; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0010817 regulation of hormone levels; GO:0002682 regulation of immune system process; GO:0006464 cellular protein modification process; GO:0003013 circulatory system process; GO:0016310 phosphorylation; GO:0002283 neutrophil activation involved in immune response; GO:0070944 neutrophil mediated killing of bacterium; GO:0044144 modulation of growth of symbiont involved in interaction with host; GO:1901700 response to oxygen-containing compound; GO:0044267 cellular protein metabolic process; GO:0048519 negative regulation of biological process; GO:0044146 negative regulation of growth of symbiont involved in interaction with host; GO:0051817 modification of morphology or physiology of other organism involved in symbiotic interaction; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0031640 killing of cells of other organism; GO:0043062 extracellular structure organization; GO:0051702 interaction with symbiont; GO:0050778 positive regulation of immune response; GO:0009617 response to bacterium; GO:0001991 regulation of systemic arterial blood pressure by circulatory renin-angiotensin; GO:0051818 disruption of cells of other organism involved in symbiotic interaction; GO:0006950 response to stress; GO:0032496 response to lipopolysaccharide; GO:0016192 vesicle-mediated transport; GO:0043900 regulation of multi-organism process; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0002263 cell activation involved in immune response; GO:0045055 regulated exocytosis; GO:0006793 phosphorus metabolic process; GO:0071219 cellular response to molecule of bacterial origin; GO:0001775 cell activation; GO:0044364 disruption of cells of other organism; GO:0051179 localization; GO:0006955 immune response; GO:0048584 positive regulation of response to stimulus; GO:0043412 macromolecule modification; GO:0006887 exocytosis; GO:1901564 organonitrogen compound metabolic process; GO:0051852 disruption by host of symbiont cells; GO:0044699 single-organism process; GO:0016485 protein processing; GO:0035821 modification of morphology or physiology of other organism; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0044126 regulation of growth of symbiont in host; GO:0022617 extracellular matrix disassembly; GO:0003073 regulation of systemic arterial blood pressure; GO:0030198 extracellular matrix organization; GO:0070887 cellular response to chemical stimulus; GO:0019731 antibacterial humoral response; GO:0002274 myeloid leukocyte activation; GO:0045926 negative regulation of growth; GO:0050829 defense response to Gram-negative bacterium; GO:0042445 hormone metabolic process; GO:0002237 response to molecule of bacterial origin; GO:0002446 neutrophil mediated immunity; GO:0050886 endocrine process; GO:0043603 cellular amide metabolic process; GO:0002003 angiotensin maturation; GO:0050830 defense response to Gram-positive bacterium; GO:0002444 myeloid leukocyte mediated immunity; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032940 secretion by cell; GO:0019222 regulation of metabolic process; GO:0043299 leukocyte degranulation; GO:0006952 defense response; GO:0036211 protein modification process; GO:0051851 modification by host of symbiont morphology or physiology; GO:0008217 regulation of blood pressure; GO:0016043 cellular component organization; GO:0040008 regulation of growth; GO:0071222 cellular response to lipopolysaccharide; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0006959 humoral immune response; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0071704 organic substance metabolic process; GO:0033993 response to lipid; GO:0071216 cellular response to biotic stimulus; GO:0006468 protein phosphorylation; GO:0002002 regulation of angiotensin levels in blood; GO:0008015 blood circulation; GO:0006508 proteolysis; GO:0070942 neutrophil mediated cytotoxicity; GO:0044130 negative regulation of growth of symbiont in host; GO:0034641 cellular nitrogen compound metabolic process; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0003008 system process; GO:0042742 defense response to bacterium; GO:0051873 killing by host of symbiont cells; GO:0006807 nitrogen compound metabolic process; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0043901 negative regulation of multi-organism process; GO:0050832 defense response to fungus; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0070943 neutrophil mediated killing of symbiont cell; GO:1901701 cellular response to oxygen-containing compound; GO:0051246 regulation of protein metabolic process; GO:0002684 positive regulation of immune system process; GO:0022411 cellular component disassembly; GO:0010467 gene expression; GO:0051604 protein maturation; GO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0034774 secretory granule lumen; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0010494 cytoplasmic stress granule; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0042582 azurophil granule; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0035770 ribonucleoprotein granule; GO:0005773 vacuole; GO:0009986 cell surface; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0008233 peptidase activity; GO:0043167 ion binding; GO:0008236 serine-type peptidase activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0008201 heparin binding; GO:1901681 sulfur compound binding; GO:0004175 endopeptidase activity; GO:0004252 serine-type endopeptidase activity; GO:0097367 carbohydrate derivative binding; GO:0003824 catalytic activity; GO:0017171 serine hydrolase activity; GO:0005488 binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0043168 anion binding; GO:0005539 glycosaminoglycan binding; ","K01319","CTSG; cathepsin G [EC:3.4.21.20]","hsa04142 Lysosome - Homo sapiens (human); hsa05322 Systemic lupus erythematosus - Homo sapiens (human); hsa04614 Renin-angiotensin system - Homo sapiens (human); hsa05146 Amoebiasis - Homo sapiens (human); hsa04080 Neuroactive ligand-receptor interaction - Homo sapiens (human); ","IPR009003; IPR001254; ","\"Peptidase S1, PA clan; Serine proteases, trypsin domain; \"\r"]
["P08397","Porphobilinogen deaminase OS=Homo sapiens OX=9606 GN=HMBS","HMBS",39.33,5.0092,6.9,2,2,2,1.03,0.934,0.903,1.131,1.092,0.918,1.096,0.306,"cytoplasm\r","GO:0051188 cofactor biosynthetic process; GO:0018160 peptidyl-pyrromethane cofactor linkage; GO:0046148 pigment biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0006783 heme biosynthetic process; GO:0044267 cellular protein metabolic process; GO:0046501 protoporphyrinogen IX metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0042168 heme metabolic process; GO:0044237 cellular metabolic process; GO:0018065 protein-cofactor linkage; GO:0071704 organic substance metabolic process; GO:0006778 porphyrin-containing compound metabolic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006782 protoporphyrinogen IX biosynthetic process; GO:0019438 aromatic compound biosynthetic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0009987 cellular process; GO:0018130 heterocycle biosynthetic process; GO:0044711 single-organism biosynthetic process; GO:0042440 pigment metabolic process; GO:0006779 porphyrin-containing compound biosynthetic process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0051186 cofactor metabolic process; GO:0018193 peptidyl-amino acid modification; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0044710 single-organism metabolic process; GO:0018198 peptidyl-cysteine modification; GO:0033013 tetrapyrrole metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0033014 tetrapyrrole biosynthetic process; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:1901362 organic cyclic compound biosynthetic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0044444 cytoplasmic part; ","GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups; GO:0004418 hydroxymethylbilane synthase activity; GO:0003824 catalytic activity; GO:0016740 transferase activity; ","K01749","hemC; hydroxymethylbilane synthase [EC:2.5.1.61]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00860 Porphyrin and chlorophyll metabolism - Homo sapiens (human); ","IPR022417; IPR022418; ","\"Porphobilinogen deaminase, N-terminal; Porphobilinogen deaminase, C-terminal; \"\r"]
["P08473","Neprilysin OS=Homo sapiens OX=9606 GN=MME","MME",85.513,7.4143,4.4,4,4,4,1.095,1.165,1.001,0.912,0.935,0.914,0.847,0.0213,"plasma membrane\r","GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0006518 peptide metabolic process; GO:0048869 cellular developmental process; GO:0034644 cellular response to UV; GO:0016486 peptide hormone processing; GO:0044699 single-organism process; GO:0016485 protein processing; GO:0060177 regulation of angiotensin metabolic process; GO:0071345 cellular response to cytokine stimulus; GO:0044237 cellular metabolic process; GO:0050877 neurological system process; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0003073 regulation of systemic arterial blood pressure; GO:0009314 response to radiation; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0070887 cellular response to chemical stimulus; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0003044 regulation of systemic arterial blood pressure mediated by a chemical signal; GO:0032502 developmental process; GO:0072338 cellular lactam metabolic process; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0042445 hormone metabolic process; GO:0007600 sensory perception; GO:0001990 regulation of systemic arterial blood pressure by hormone; GO:0034097 response to cytokine; GO:0071214 cellular response to abiotic stimulus; GO:0080090 regulation of primary metabolic process; GO:0002446 neutrophil mediated immunity; GO:0050886 endocrine process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0002003 angiotensin maturation; GO:0043603 cellular amide metabolic process; GO:0032501 multicellular organismal process; GO:0002444 myeloid leukocyte mediated immunity; GO:0006810 transport; GO:0071482 cellular response to light stimulus; GO:0048513 animal organ development; GO:0001655 urogenital system development; GO:0050789 regulation of biological process; GO:0007569 cell aging; GO:0042221 response to chemical; GO:0032940 secretion by cell; GO:0044710 single-organism metabolic process; GO:0007568 aging; GO:0019222 regulation of metabolic process; GO:0010817 regulation of hormone levels; GO:0043299 leukocyte degranulation; GO:0003013 circulatory system process; GO:0048856 anatomical structure development; GO:0071492 cellular response to UV-A; GO:0008217 regulation of blood pressure; GO:0044707 single-multicellular organism process; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0009628 response to abiotic stimulus; GO:0060255 regulation of macromolecule metabolic process; GO:0070141 response to UV-A; GO:0071310 cellular response to organic substance; GO:0050435 beta-amyloid metabolic process; GO:0072001 renal system development; GO:0019233 sensory perception of pain; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0071493 cellular response to UV-B; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0090399 replicative senescence; GO:0002002 regulation of angiotensin levels in blood; GO:0008015 blood circulation; GO:0034641 cellular nitrogen compound metabolic process; GO:0006508 proteolysis; GO:0036230 granulocyte activation; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0071478 cellular response to radiation; GO:0001991 regulation of systemic arterial blood pressure by circulatory renin-angiotensin; GO:0001822 kidney development; GO:0046449 creatinine metabolic process; GO:0003008 system process; GO:0009416 response to light stimulus; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0006807 nitrogen compound metabolic process; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0043312 neutrophil degranulation; GO:0044238 primary metabolic process; GO:0002263 cell activation involved in immune response; GO:0002366 leukocyte activation involved in immune response; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:0009411 response to UV; GO:0051246 regulation of protein metabolic process; GO:0010224 response to UV-B; GO:0044767 single-organism developmental process; GO:0001775 cell activation; GO:0010467 gene expression; GO:0051179 localization; GO:0006955 immune response; GO:0051604 protein maturation; GO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin; GO:0006887 exocytosis; GO:0065007 biological regulation; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0030425 dendrite; GO:0044421 extracellular region part; GO:0098862 cluster of actin-based cell projections; GO:0005903 brush border; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0070382 exocytic vesicle; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0008021 synaptic vesicle; GO:0098793 presynapse; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0098805 whole membrane; GO:0099503 secretory vesicle; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0030141 secretory granule; GO:0030055 cell-substrate junction; GO:0044306 neuron projection terminus; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0044456 synapse part; GO:0005924 cell-substrate adherens junction; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0031226 intrinsic component of plasma membrane; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0044463 cell projection part; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0045202 synapse; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0030424 axon; GO:0043226 organelle; GO:0030667 secretory granule membrane; GO:0036477 somatodendritic compartment; GO:0044459 plasma membrane part; GO:0030133 transport vesicle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0004175 endopeptidase activity; GO:0008238 exopeptidase activity; GO:0004222 metalloendopeptidase activity; GO:0008233 peptidase activity; GO:0046914 transition metal ion binding; GO:0042277 peptide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0008237 metallopeptidase activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0033218 amide binding; GO:0008270 zinc ion binding; ","K01389","MME; neprilysin [EC:3.4.24.11]","hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04974 Protein digestion and absorption - Homo sapiens (human); hsa04614 Renin-angiotensin system - Homo sapiens (human); hsa04640 Hematopoietic cell lineage - Homo sapiens (human); ","IPR008753; IPR024079; IPR018497; ","\"Peptidase M13, N-terminal domain; Metallopeptidase, catalytic domain; Peptidase M13, C-terminal domain; \"\r"]
["P08514","Integrin alpha-IIb OS=Homo sapiens OX=9606 GN=ITGA2B","ITGA2B",113.38,15.581,6.2,6,6,6,0.895,1.045,0.952,1.125,1.078,1.013,1.112,0.12,"plasma membrane\r","GO:0044700 single organism signaling; GO:0030335 positive regulation of cell migration; GO:0065008 regulation of biological quality; GO:0007596 blood coagulation; GO:0007166 cell surface receptor signaling pathway; GO:0040017 positive regulation of locomotion; GO:0044699 single-organism process; GO:0051234 establishment of localization; GO:0009611 response to wounding; GO:0022610 biological adhesion; GO:0016337 single organismal cell-cell adhesion; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0032879 regulation of localization; GO:0007160 cell-matrix adhesion; GO:0007155 cell adhesion; GO:0030198 extracellular matrix organization; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0051716 cellular response to stimulus; GO:0030168 platelet activation; GO:0098609 cell-cell adhesion; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0051272 positive regulation of cellular component movement; GO:0023052 signaling; GO:0007229 integrin-mediated signaling pathway; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0032940 secretion by cell; GO:0098602 single organism cell adhesion; GO:0002682 regulation of immune system process; GO:0002685 regulation of leukocyte migration; GO:0050817 coagulation; GO:0002687 positive regulation of leukocyte migration; GO:0070527 platelet aggregation; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0002576 platelet degranulation; GO:2000147 positive regulation of cell motility; GO:0050896 response to stimulus; GO:0034109 homotypic cell-cell adhesion; GO:0007599 hemostasis; GO:1902578 single-organism localization; GO:0043062 extracellular structure organization; GO:2000145 regulation of cell motility; GO:0009987 cellular process; GO:0050878 regulation of body fluid levels; GO:0006950 response to stress; GO:0051270 regulation of cellular component movement; GO:0016192 vesicle-mediated transport; GO:0030334 regulation of cell migration; GO:0048518 positive regulation of biological process; GO:0045055 regulated exocytosis; GO:0042060 wound healing; GO:0031589 cell-substrate adhesion; GO:0002684 positive regulation of immune system process; GO:0001775 cell activation; GO:0040012 regulation of locomotion; GO:0051179 localization; GO:0065007 biological regulation; GO:0006887 exocytosis; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0098636 protein complex involved in cell adhesion; GO:0009897 external side of plasma membrane; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0030054 cell junction; GO:0098796 membrane protein complex; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0099503 secretory vesicle; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0031092 platelet alpha granule membrane; GO:0098552 side of membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0031226 intrinsic component of plasma membrane; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0098802 plasma membrane receptor complex; GO:0098797 plasma membrane protein complex; GO:0070161 anchoring junction; GO:0043235 receptor complex; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0008305 integrin complex; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0030667 secretory granule membrane; GO:0072562 blood microparticle; GO:0044459 plasma membrane part; GO:0009986 cell surface; GO:0031091 platelet alpha granule; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0042802 identical protein binding; GO:0005488 binding; GO:0043167 ion binding; GO:0044877 macromolecular complex binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0050840 extracellular matrix binding; GO:0032403 protein complex binding; GO:0070051 fibrinogen binding; ","K06476","ITGA2B; integrin alpha 2B","hsa04015 Rap1 signaling pathway - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa05414 Dilated cardiomyopathy (DCM) - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa04640 Hematopoietic cell lineage - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa05222 Small cell lung cancer - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa04611 Platelet activation - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human); hsa04512 ECM-receptor interaction - Homo sapiens (human); hsa05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human); hsa05410 Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human); ","IPR032695; IPR013649; ","Integrin domain; Integrin alpha-2; \r"]
["P08559","Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial OS=Homo sapiens OX=9606 GN=PDHA1","PDHA1",43.295,75.017,33.8,13,24,13,1.086,1.043,1.063,0.959,0.94,0.941,0.89,0.000942,"mitochondria\r","GO:0051188 cofactor biosynthetic process; GO:0019362 pyridine nucleotide metabolic process; GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0019216 regulation of lipid metabolic process; GO:0072524 pyridine-containing compound metabolic process; GO:0044237 cellular metabolic process; GO:0035384 thioester biosynthetic process; GO:0044272 sulfur compound biosynthetic process; GO:0006796 phosphate-containing compound metabolic process; GO:0006006 glucose metabolic process; GO:0006085 acetyl-CoA biosynthetic process; GO:0051196 regulation of coenzyme metabolic process; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0006753 nucleoside phosphate metabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0009108 coenzyme biosynthetic process; GO:0046487 glyoxylate metabolic process; GO:0006790 sulfur compound metabolic process; GO:0051193 regulation of cofactor metabolic process; GO:0072350 tricarboxylic acid metabolic process; GO:0051174 regulation of phosphorus metabolic process; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0071616 acyl-CoA biosynthetic process; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006081 cellular aldehyde metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0006732 coenzyme metabolic process; GO:0006084 acetyl-CoA metabolic process; GO:0005975 carbohydrate metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0051186 cofactor metabolic process; GO:0010565 regulation of cellular ketone metabolic process; GO:0006101 citrate metabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0050789 regulation of biological process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0019222 regulation of metabolic process; GO:0006082 organic acid metabolic process; GO:0042762 regulation of sulfur metabolic process; GO:0043436 oxoacid metabolic process; GO:0050794 regulation of cellular process; GO:0006725 cellular aromatic compound metabolic process; GO:0046496 nicotinamide nucleotide metabolic process; GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate; GO:0071704 organic substance metabolic process; GO:0006090 pyruvate metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0050812 regulation of acyl-CoA biosynthetic process; GO:0005996 monosaccharide metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0044711 single-organism biosynthetic process; GO:0006099 tricarboxylic acid cycle; GO:0035383 thioester metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0045333 cellular respiration; GO:0044249 cellular biosynthetic process; GO:0006637 acyl-CoA metabolic process; GO:0019217 regulation of fatty acid metabolic process; GO:0006793 phosphorus metabolic process; GO:0009060 aerobic respiration; GO:0019752 carboxylic acid metabolic process; GO:0019637 organophosphate metabolic process; GO:0006086 acetyl-CoA biosynthetic process from pyruvate; GO:0019318 hexose metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005730 nucleolus; GO:0045254 pyruvate dehydrogenase complex; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0043209 myelin sheath; GO:0044464 cell part; GO:0005622 intracellular; GO:1990204 oxidoreductase complex; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; GO:0034603 pyruvate dehydrogenase [NAD(P)+] activity; GO:0034604 pyruvate dehydrogenase (NAD+) activity; GO:0003824 catalytic activity; GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors; GO:0004738 pyruvate dehydrogenase activity; GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity; GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor; GO:0016491 oxidoreductase activity; ","K00161","PDHA; pyruvate dehydrogenase E1 component alpha subunit [EC:1.2.4.1]","hsa00620 Pyruvate metabolism - Homo sapiens (human); hsa04066 HIF-1 signaling pathway - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00020 Citrate cycle (TCA cycle) - Homo sapiens (human); hsa04922 Glucagon signaling pathway - Homo sapiens (human); hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); hsa05230 Central carbon metabolism in cancer - Homo sapiens (human); ","IPR001017; IPR029061; ","\"Dehydrogenase, E1 component; Thiamin diphosphate-binding fold; \"\r"]
["P08567","Pleckstrin OS=Homo sapiens OX=9606 GN=PLEK","PLEK",40.124,9.9195,8,2,2,2,0.9,0.906,0.917,1.088,1.061,1.124,1.202,0.000476,"cytoplasm\r","GO:0044700 single organism signaling; GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0007166 cell surface receptor signaling pathway; GO:0043243 positive regulation of protein complex disassembly; GO:0044255 cellular lipid metabolic process; GO:0030832 regulation of actin filament length; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0022610 biological adhesion; GO:0008152 metabolic process; GO:0030036 actin cytoskeleton organization; GO:0051240 positive regulation of multicellular organismal process; GO:0044093 positive regulation of molecular function; GO:0032535 regulation of cellular component size; GO:0060305 regulation of cell diameter; GO:1902931 negative regulation of alcohol biosynthetic process; GO:0007155 cell adhesion; GO:0090303 positive regulation of wound healing; GO:0009306 protein secretion; GO:0010562 positive regulation of phosphorus metabolic process; GO:0051493 regulation of cytoskeleton organization; GO:0008104 protein localization; GO:0030194 positive regulation of blood coagulation; GO:0010677 negative regulation of cellular carbohydrate metabolic process; GO:0010920 negative regulation of inositol phosphate biosynthetic process; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0051716 cellular response to stimulus; GO:0002244 hematopoietic progenitor cell differentiation; GO:0051174 regulation of phosphorus metabolic process; GO:0006904 vesicle docking involved in exocytosis; GO:0080090 regulation of primary metabolic process; GO:0010919 regulation of inositol phosphate biosynthetic process; GO:0030168 platelet activation; GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway; GO:0044763 single-organism cellular process; GO:0002520 immune system development; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:1901881 positive regulation of protein depolymerization; GO:0006810 transport; GO:0031532 actin cytoskeleton reorganization; GO:0048513 animal organ development; GO:1902532 negative regulation of intracellular signal transduction; GO:0051336 regulation of hydrolase activity; GO:1900048 positive regulation of hemostasis; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0098602 single organism cell adhesion; GO:1902905 positive regulation of supramolecular fiber organization; GO:0050817 coagulation; GO:0032233 positive regulation of actin filament bundle assembly; GO:0030834 regulation of actin filament depolymerization; GO:1903036 positive regulation of response to wounding; GO:1902903 regulation of supramolecular fiber organization; GO:0050794 regulation of cellular process; GO:0043255 regulation of carbohydrate biosynthetic process; GO:0044707 single-multicellular organism process; GO:0032956 regulation of actin cytoskeleton organization; GO:0010543 regulation of platelet activation; GO:0030193 regulation of blood coagulation; GO:0002576 platelet degranulation; GO:0080134 regulation of response to stress; GO:0010925 positive regulation of inositol-polyphosphate 5-phosphatase activity; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:1902930 regulation of alcohol biosynthetic process; GO:0034109 homotypic cell-cell adhesion; GO:0051239 regulation of multicellular organismal process; GO:0010922 positive regulation of phosphatase activity; GO:0031529 ruffle organization; GO:0050867 positive regulation of cell activation; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:1902578 single-organism localization; GO:0051345 positive regulation of hydrolase activity; GO:0009889 regulation of biosynthetic process; GO:0050848 regulation of calcium-mediated signaling; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0009966 regulation of signal transduction; GO:1902531 regulation of intracellular signal transduction; GO:0006950 response to stress; GO:0051495 positive regulation of cytoskeleton organization; GO:0032231 regulation of actin filament bundle assembly; GO:0048731 system development; GO:1901879 regulation of protein depolymerization; GO:0016192 vesicle-mediated transport; GO:0032101 regulation of response to external stimulus; GO:0032970 regulation of actin filament-based process; GO:0002376 immune system process; GO:0071702 organic substance transport; GO:0006109 regulation of carbohydrate metabolic process; GO:0044238 primary metabolic process; GO:0048278 vesicle docking; GO:0009892 negative regulation of metabolic process; GO:0050849 negative regulation of calcium-mediated signaling; GO:0007186 G-protein coupled receptor signaling pathway; GO:0045184 establishment of protein localization; GO:0008064 regulation of actin polymerization or depolymerization; GO:0009890 negative regulation of biosynthetic process; GO:0045055 regulated exocytosis; GO:0045912 negative regulation of carbohydrate metabolic process; GO:0061041 regulation of wound healing; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0030029 actin filament-based process; GO:0001775 cell activation; GO:0019637 organophosphate metabolic process; GO:0006644 phospholipid metabolic process; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:1903034 regulation of response to wounding; GO:0045936 negative regulation of phosphate metabolic process; GO:0006887 exocytosis; GO:0046486 glycerolipid metabolic process; GO:0009968 negative regulation of signal transduction; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0009611 response to wounding; GO:0051130 positive regulation of cellular component organization; GO:0016337 single organismal cell-cell adhesion; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:1900046 regulation of hemostasis; GO:0006650 glycerophospholipid metabolic process; GO:0035303 regulation of dephosphorylation; GO:0031334 positive regulation of protein complex assembly; GO:0046488 phosphatidylinositol metabolic process; GO:0033036 macromolecule localization; GO:0033625 positive regulation of integrin activation; GO:0006629 lipid metabolic process; GO:0032502 developmental process; GO:0030836 positive regulation of actin filament depolymerization; GO:0070560 protein secretion by platelet; GO:0045937 positive regulation of phosphate metabolic process; GO:0031326 regulation of cellular biosynthetic process; GO:0030866 cortical actin cytoskeleton organization; GO:0010675 regulation of cellular carbohydrate metabolic process; GO:0098609 cell-cell adhesion; GO:0048522 positive regulation of cellular process; GO:0008277 regulation of G-protein coupled receptor protein signaling pathway; GO:0023052 signaling; GO:0007229 integrin-mediated signaling pathway; GO:1902589 single-organism organelle organization; GO:0043254 regulation of protein complex assembly; GO:0050865 regulation of cell activation; GO:0050789 regulation of biological process; GO:0035306 positive regulation of dephosphorylation; GO:0010638 positive regulation of organelle organization; GO:0030030 cell projection organization; GO:0032940 secretion by cell; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0043244 regulation of protein complex disassembly; GO:0019220 regulation of phosphate metabolic process; GO:0048856 anatomical structure development; GO:0070493 thrombin-activated receptor signaling pathway; GO:0070527 platelet aggregation; GO:0016043 cellular component organization; GO:0044087 regulation of cellular component biogenesis; GO:0031324 negative regulation of cellular metabolic process; GO:0030865 cortical cytoskeleton organization; GO:0050896 response to stimulus; GO:0022406 membrane docking; GO:0007599 hemostasis; GO:0071704 organic substance metabolic process; GO:0033623 regulation of integrin activation; GO:0030154 cell differentiation; GO:0070528 protein kinase C signaling; GO:0008361 regulation of cell size; GO:0030845 phospholipase C-inhibiting G-protein coupled receptor signaling pathway; GO:0009987 cellular process; GO:0050878 regulation of body fluid levels; GO:0010921 regulation of phosphatase activity; GO:0035556 intracellular signal transduction; GO:0033043 regulation of organelle organization; GO:0010924 regulation of inositol-polyphosphate 5-phosphatase activity; GO:0050820 positive regulation of coagulation; GO:0048585 negative regulation of response to stimulus; GO:0048518 positive regulation of biological process; GO:0048534 hematopoietic or lymphoid organ development; GO:0030097 hemopoiesis; GO:0043085 positive regulation of catalytic activity; GO:0050818 regulation of coagulation; GO:0042060 wound healing; GO:0044767 single-organism developmental process; GO:0010563 negative regulation of phosphorus metabolic process; GO:0090066 regulation of anatomical structure size; GO:0031327 negative regulation of cellular biosynthetic process; GO:0010572 positive regulation of platelet activation; GO:0051128 regulation of cellular component organization; GO:0044089 positive regulation of cellular component biogenesis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0031252 cell leading edge; GO:0016020 membrane; GO:0042995 cell projection; GO:0071944 cell periphery; GO:0032587 ruffle membrane; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0098590 plasma membrane region; GO:0044459 plasma membrane part; GO:0031256 leading edge membrane; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0031253 cell projection membrane; GO:0001726 ruffle; GO:0044444 cytoplasmic part; ","GO:1901981 phosphatidylinositol phosphate binding; GO:0019901 protein kinase binding; GO:0046983 protein dimerization activity; GO:0043167 ion binding; GO:0005515 protein binding; GO:0019900 kinase binding; GO:0043325 phosphatidylinositol-3,4-bisphosphate binding; GO:1902936 phosphatidylinositol bisphosphate binding; GO:0042802 identical protein binding; GO:0005488 binding; GO:0042803 protein homodimerization activity; GO:0035091 phosphatidylinositol binding; GO:0005543 phospholipid binding; GO:0008289 lipid binding; GO:0005080 protein kinase C binding; GO:0043168 anion binding; GO:0019899 enzyme binding; ","K19993",null,null,"IPR011991; IPR011993; IPR000591; IPR001849; ","Winged helix-turn-helix DNA-binding domain; PH domain-like; DEP domain; Pleckstrin homology domain; \r"]
["P08571","Monocyte differentiation antigen CD14 OS=Homo sapiens OX=9606 GN=CD14","CD14",40.076,60.931,24.3,7,10,7,0.891,0.87,0.928,1.055,1.154,0.955,1.177,0.0504,"extracellular\r","GO:0060627 regulation of vesicle-mediated transport; GO:0044700 single organism signaling; GO:0032481 positive regulation of type I interferon production; GO:0045321 leukocyte activation; GO:0032680 regulation of tumor necrosis factor production; GO:0007166 cell surface receptor signaling pathway; GO:0032760 positive regulation of tumor necrosis factor production; GO:0031347 regulation of defense response; GO:0070391 response to lipoteichoic acid; GO:0009607 response to biotic stimulus; GO:0009605 response to external stimulus; GO:0051240 positive regulation of multicellular organismal process; GO:0009408 response to heat; GO:0032879 regulation of localization; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0002758 innate immune response-activating signal transduction; GO:0044763 single-organism cellular process; GO:0050707 regulation of cytokine secretion; GO:0051704 multi-organism process; GO:0071396 cellular response to lipid; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0048583 regulation of response to stimulus; GO:0050714 positive regulation of protein secretion; GO:0051223 regulation of protein transport; GO:0002682 regulation of immune system process; GO:0002755 MyD88-dependent toll-like receptor signaling pathway; GO:0051047 positive regulation of secretion; GO:0050794 regulation of cellular process; GO:0002283 neutrophil activation involved in immune response; GO:0097190 apoptotic signaling pathway; GO:0009628 response to abiotic stimulus; GO:0001819 positive regulation of cytokine production; GO:0038123 toll-like receptor TLR1:TLR2 signaling pathway; GO:1901700 response to oxygen-containing compound; GO:0071221 cellular response to bacterial lipopeptide; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:0051239 regulation of multicellular organismal process; GO:0032729 positive regulation of interferon-gamma production; GO:0023057 negative regulation of signaling; GO:0031349 positive regulation of defense response; GO:0010648 negative regulation of cell communication; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0032880 regulation of protein localization; GO:0006898 receptor-mediated endocytosis; GO:0009966 regulation of signal transduction; GO:0050778 positive regulation of immune response; GO:0009617 response to bacterium; GO:0002253 activation of immune response; GO:0030100 regulation of endocytosis; GO:0006950 response to stress; GO:0032496 response to lipopolysaccharide; GO:0016192 vesicle-mediated transport; GO:0051602 response to electrical stimulus; GO:1903557 positive regulation of tumor necrosis factor superfamily cytokine production; GO:0097305 response to alcohol; GO:0002376 immune system process; GO:0097300 programmed necrotic cell death; GO:0010033 response to organic substance; GO:0002263 cell activation involved in immune response; GO:0002756 MyD88-independent toll-like receptor signaling pathway; GO:0045055 regulated exocytosis; GO:1904951 positive regulation of establishment of protein localization; GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway; GO:0071219 cellular response to molecule of bacterial origin; GO:0001775 cell activation; GO:0007249 I-kappaB kinase/NF-kappaB signaling; GO:0012501 programmed cell death; GO:0070266 necroptotic process; GO:0051179 localization; GO:0006955 immune response; GO:0048584 positive regulation of response to stimulus; GO:0006887 exocytosis; GO:1903555 regulation of tumor necrosis factor superfamily cytokine production; GO:0071725 response to triacyl bacterial lipopeptide; GO:0009968 negative regulation of signal transduction; GO:0032026 response to magnesium ion; GO:0023051 regulation of signaling; GO:0051046 regulation of secretion; GO:0044699 single-organism process; GO:0006909 phagocytosis; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0034127 regulation of MyD88-independent toll-like receptor signaling pathway; GO:0007154 cell communication; GO:0045088 regulation of innate immune response; GO:0006915 apoptotic process; GO:0071726 cellular response to diacyl bacterial lipopeptide; GO:0002221 pattern recognition receptor signaling pathway; GO:0010035 response to inorganic substance; GO:0034612 response to tumor necrosis factor; GO:0070887 cellular response to chemical stimulus; GO:0002274 myeloid leukocyte activation; GO:0034121 regulation of toll-like receptor signaling pathway; GO:0034097 response to cytokine; GO:0002237 response to molecule of bacterial origin; GO:0070265 necrotic cell death; GO:0002446 neutrophil mediated immunity; GO:0048522 positive regulation of cellular process; GO:1903530 regulation of secretion by cell; GO:0023052 signaling; GO:0002764 immune response-regulating signaling pathway; GO:0010038 response to metal ion; GO:0002444 myeloid leukocyte mediated immunity; GO:0051050 positive regulation of transport; GO:0002683 negative regulation of immune system process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0071223 cellular response to lipoteichoic acid; GO:0071727 cellular response to triacyl bacterial lipopeptide; GO:1903532 positive regulation of secretion by cell; GO:0070339 response to bacterial lipopeptide; GO:0032940 secretion by cell; GO:0002224 toll-like receptor signaling pathway; GO:0006954 inflammatory response; GO:0043299 leukocyte degranulation; GO:0006952 defense response; GO:0050715 positive regulation of cytokine secretion; GO:0071724 response to diacyl bacterial lipopeptide; GO:0051222 positive regulation of protein transport; GO:0071220 cellular response to bacterial lipoprotein; GO:0035666 TRIF-dependent toll-like receptor signaling pathway; GO:0002218 activation of innate immune response; GO:0032479 regulation of type I interferon production; GO:0071222 cellular response to lipopolysaccharide; GO:0038124 toll-like receptor TLR6:TLR2 signaling pathway; GO:0002252 immune effector process; GO:0034122 negative regulation of toll-like receptor signaling pathway; GO:0045807 positive regulation of endocytosis; GO:0071310 cellular response to organic substance; GO:0045471 response to ethanol; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0031663 lipopolysaccharide-mediated signaling pathway; GO:0070201 regulation of establishment of protein localization; GO:0045087 innate immune response; GO:0033993 response to lipid; GO:0071216 cellular response to biotic stimulus; GO:0009266 response to temperature stimulus; GO:0002757 immune response-activating signal transduction; GO:0032493 response to bacterial lipoprotein; GO:0036230 granulocyte activation; GO:0050708 regulation of protein secretion; GO:0009987 cellular process; GO:0032649 regulation of interferon-gamma production; GO:0045089 positive regulation of innate immune response; GO:0035556 intracellular signal transduction; GO:0051049 regulation of transport; GO:0048585 negative regulation of response to stimulus; GO:0006897 endocytosis; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0034142 toll-like receptor 4 signaling pathway; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:1901701 cellular response to oxygen-containing compound; GO:0008219 cell death; GO:0002684 positive regulation of immune system process; GO:0001817 regulation of cytokine production; GO:0051128 regulation of cellular component organization; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0009897 external side of plasma membrane; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0098857 membrane microdomain; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0046696 lipopolysaccharide receptor complex; GO:0044433 cytoplasmic vesicle part; GO:0031224 intrinsic component of membrane; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0099503 secretory vesicle; GO:0098805 whole membrane; GO:0098589 membrane region; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0030141 secretory granule; GO:0045121 membrane raft; GO:0043227 membrane-bounded organelle; GO:0031233 intrinsic component of external side of plasma membrane; GO:0098552 side of membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0010008 endosome membrane; GO:0031226 intrinsic component of plasma membrane; GO:0098588 bounding membrane of organelle; GO:0031225 anchored component of membrane; GO:0044446 intracellular organelle part; GO:0043235 receptor complex; GO:0012506 vesicle membrane; GO:0044440 endosomal part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0046658 anchored component of plasma membrane; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031362 anchored component of external side of plasma membrane; GO:0030667 secretory granule membrane; GO:0044459 plasma membrane part; GO:0009986 cell surface; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0038023 signaling receptor activity; GO:0016019 peptidoglycan receptor activity; GO:0005515 protein binding; GO:0004888 transmembrane signaling receptor activity; GO:0004871 signal transducer activity; GO:0070891 lipoteichoic acid binding; GO:0060089 molecular transducer activity; GO:0097367 carbohydrate derivative binding; GO:0004872 receptor activity; GO:0001847 opsonin receptor activity; GO:0005488 binding; GO:0008289 lipid binding; GO:0001530 lipopolysaccharide binding; GO:0038187 pattern recognition receptor activity; GO:0008329 signaling pattern recognition receptor activity; GO:0099600 transmembrane receptor activity; ","K04391","CD14; monocyte differentiation antigen CD14","hsa05132 Salmonella infection - Homo sapiens (human); hsa05152 Tuberculosis - Homo sapiens (human); hsa04620 Toll-like receptor signaling pathway - Homo sapiens (human); hsa05221 Acute myeloid leukemia - Homo sapiens (human); hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human); hsa04640 Hematopoietic cell lineage - Homo sapiens (human); hsa05146 Amoebiasis - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa05134 Legionellosis - Homo sapiens (human); hsa05133 Pertussis - Homo sapiens (human); hsa04010 MAPK signaling pathway - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human); hsa04064 NF-kappa B signaling pathway - Homo sapiens (human); ","IPR032675; ","\"Leucine-rich repeat domain, L domain-like; \"\r"]
["P08572","Collagen alpha-2(IV) chain OS=Homo sapiens OX=9606 GN=COL4A2","COL4A2",167.55,45.239,5.4,7,14,7,1.148,1.031,1.113,0.962,0.877,0.898,0.831,0.0121,"extracellular\r","GO:0044700 single organism signaling; GO:0051093 negative regulation of developmental process; GO:0007166 cell surface receptor signaling pathway; GO:0001568 blood vessel development; GO:0097659 nucleic acid-templated transcription; GO:0048869 cellular developmental process; GO:0044236 multicellular organism metabolic process; GO:0071560 cellular response to transforming growth factor beta stimulus; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0071363 cellular response to growth factor stimulus; GO:0044237 cellular metabolic process; GO:0007492 endoderm development; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0001525 angiogenesis; GO:0007154 cell communication; GO:0009719 response to endogenous stimulus; GO:0070848 response to growth factor; GO:0030198 extracellular matrix organization; GO:0043170 macromolecule metabolic process; GO:0048514 blood vessel morphogenesis; GO:0009790 embryo development; GO:0044259 multicellular organismal macromolecule metabolic process; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0070887 cellular response to chemical stimulus; GO:0048598 embryonic morphogenesis; GO:0030574 collagen catabolic process; GO:2000181 negative regulation of blood vessel morphogenesis; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0009888 tissue development; GO:0001704 formation of primary germ layer; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:1901360 organic cyclic compound metabolic process; GO:0001944 vasculature development; GO:0038065 collagen-activated signaling pathway; GO:0032774 RNA biosynthetic process; GO:0023052 signaling; GO:0071559 response to transforming growth factor beta; GO:1901343 negative regulation of vasculature development; GO:0032501 multicellular organismal process; GO:0016070 RNA metabolic process; GO:0016525 negative regulation of angiogenesis; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0045765 regulation of angiogenesis; GO:0048856 anatomical structure development; GO:1901362 organic cyclic compound biosynthetic process; GO:2000026 regulation of multicellular organismal development; GO:0050794 regulation of cellular process; GO:0072359 circulatory system development; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0006725 cellular aromatic compound metabolic process; GO:0071310 cellular response to organic substance; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:0071704 organic substance metabolic process; GO:0007369 gastrulation; GO:0009653 anatomical structure morphogenesis; GO:0044243 multicellular organismal catabolic process; GO:0030154 cell differentiation; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0043062 extracellular structure organization; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0001706 endoderm formation; GO:0035987 endodermal cell differentiation; GO:0044712 single-organism catabolic process; GO:0048731 system development; GO:1901342 regulation of vasculature development; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0072358 cardiovascular system development; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0071495 cellular response to endogenous stimulus; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0032963 collagen metabolic process; GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway; GO:0010467 gene expression; GO:0009056 catabolic process; GO:0050793 regulation of developmental process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0005587 collagen type IV trimer; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0044420 extracellular matrix component; GO:0005581 collagen trimer; GO:0044422 organelle part; GO:0005604 basement membrane; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005788 endoplasmic reticulum lumen; GO:0098644 complex of collagen trimers; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0099081 supramolecular polymer; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031012 extracellular matrix; GO:0044432 endoplasmic reticulum part; GO:0098651 basement membrane collagen trimer; GO:0005578 proteinaceous extracellular matrix; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0098645 collagen network; GO:0098642 network-forming collagen trimer; GO:0044444 cytoplasmic part; ","GO:0005201 extracellular matrix structural constituent; GO:0005515 protein binding; GO:0005198 structural molecule activity; GO:0005488 binding; ","K06237","COL4A; collagen, type IV, alpha","hsa05200 Pathways in cancer - Homo sapiens (human); hsa04933 AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa05146 Amoebiasis - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa05222 Small cell lung cancer - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa04512 ECM-receptor interaction - Homo sapiens (human); hsa04974 Protein digestion and absorption - Homo sapiens (human); hsa04926 Relaxin signaling pathway - Homo sapiens (human); ","IPR016187; ","C-type lectin fold; \r"]
["P08574","Cytochrome c1, heme protein, mitochondrial OS=Homo sapiens OX=9606 GN=CYC1","CYC1",35.422,37.169,20,8,11,8,0.972,0.896,1.002,1.031,1.027,1.041,1.08,0.147,"mitochondria\r","GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0006839 mitochondrial transport; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0046129 purine ribonucleoside biosynthetic process; GO:0009163 nucleoside biosynthetic process; GO:0009156 ribonucleoside monophosphate biosynthetic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c; GO:0051234 establishment of localization; GO:0046390 ribose phosphate biosynthetic process; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0006091 generation of precursor metabolites and energy; GO:1901137 carbohydrate derivative biosynthetic process; GO:0006753 nucleoside phosphate metabolic process; GO:0009719 response to endogenous stimulus; GO:0019693 ribose phosphate metabolic process; GO:1901652 response to peptide; GO:0009145 purine nucleoside triphosphate biosynthetic process; GO:0044765 single-organism transport; GO:0018130 heterocycle biosynthetic process; GO:0098655 cation transmembrane transport; GO:0009206 purine ribonucleoside triphosphate biosynthetic process; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0006119 oxidative phosphorylation; GO:0006754 ATP biosynthetic process; GO:0044763 single-organism cellular process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0015985 energy coupled proton transport, down electrochemical gradient; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0009168 purine ribonucleoside monophosphate biosynthetic process; GO:1902582 single-organism intracellular transport; GO:0042451 purine nucleoside biosynthetic process; GO:0090407 organophosphate biosynthetic process; GO:0006810 transport; GO:0010243 response to organonitrogen compound; GO:0042221 response to chemical; GO:0043434 response to peptide hormone; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0072522 purine-containing compound biosynthetic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:1901698 response to nitrogen compound; GO:0015986 ATP synthesis coupled proton transport; GO:0022900 electron transport chain; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0006164 purine nucleotide biosynthetic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0098662 inorganic cation transmembrane transport; GO:0009201 ribonucleoside triphosphate biosynthetic process; GO:0016310 phosphorylation; GO:0046907 intracellular transport; GO:0034220 ion transmembrane transport; GO:0009165 nucleotide biosynthetic process; GO:0042776 mitochondrial ATP synthesis coupled proton transport; GO:0006725 cellular aromatic compound metabolic process; GO:0042773 ATP synthesis coupled electron transport; GO:0009259 ribonucleotide metabolic process; GO:0009142 nucleoside triphosphate biosynthetic process; GO:1901700 response to oxygen-containing compound; GO:0022904 respiratory electron transport chain; GO:0050896 response to stimulus; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0006812 cation transport; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:1990542 mitochondrial transmembrane transport; GO:1901135 carbohydrate derivative metabolic process; GO:1902600 hydrogen ion transmembrane transport; GO:0034641 cellular nitrogen compound metabolic process; GO:1902580 single-organism cellular localization; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0009119 ribonucleoside metabolic process; GO:0046034 ATP metabolic process; GO:0009124 nucleoside monophosphate biosynthetic process; GO:0044711 single-organism biosynthetic process; GO:0098660 inorganic ion transmembrane transport; GO:0009127 purine nucleoside monophosphate biosynthetic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0042455 ribonucleoside biosynthetic process; GO:0045333 cellular respiration; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0006163 purine nucleotide metabolic process; GO:0006818 hydrogen transport; GO:0015992 proton transport; GO:0051641 cellular localization; GO:0046128 purine ribonucleoside metabolic process; GO:0055085 transmembrane transport; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0009152 purine ribonucleotide biosynthetic process; GO:0006793 phosphorus metabolic process; GO:1901659 glycosyl compound biosynthetic process; GO:0006811 ion transport; GO:0009260 ribonucleotide biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0033762 response to glucagon; GO:0009150 purine ribonucleotide metabolic process; GO:0009725 response to hormone; GO:0051179 localization; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:0015672 monovalent inorganic cation transport; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:1902494 catalytic complex; GO:0005750 mitochondrial respiratory chain complex III; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0019866 organelle inner membrane; GO:1990351 transporter complex; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0098803 respiratory chain complex; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0070069 cytochrome complex; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:1902495 transmembrane transporter complex; GO:0045275 respiratory chain complex III; GO:0016021 integral component of membrane; GO:0005739 mitochondrion; GO:0005746 mitochondrial respiratory chain; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:1990204 oxidoreductase complex; GO:0031975 envelope; GO:0043234 protein complex; GO:0070469 respiratory chain; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0009055 electron carrier activity; GO:0020037 heme binding; GO:0005488 binding; GO:0043167 ion binding; GO:0046872 metal ion binding; GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity; GO:0043169 cation binding; GO:0046906 tetrapyrrole binding; GO:0045153 electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity; ","K00413","CYC1; ubiquinol-cytochrome c reductase cytochrome c1 subunit","hsa04260 Cardiac muscle contraction - Homo sapiens (human); hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); ","IPR021157; IPR009056; ","\"Cytochrome c1, transmembrane anchor, C-terminal; Cytochrome c-like domain; \"\r"]
["P08575","Receptor-type tyrosine-protein phosphatase C OS=Homo sapiens OX=9606 GN=PTPRC","PTPRC",147.48,39.732,9.3,12,16,12,0.909,0.892,0.886,1.131,1.082,1.102,1.234,1.45E-4,"peroxisome\r","GO:0044700 single organism signaling; GO:0002694 regulation of leukocyte activation; GO:0098542 defense response to other organism; GO:0002698 negative regulation of immune effector process; GO:0044237 cellular metabolic process; GO:0009607 response to biotic stimulus; GO:0042110 T cell activation; GO:0030888 regulation of B cell proliferation; GO:0008152 metabolic process; GO:0032946 positive regulation of mononuclear cell proliferation; GO:0044093 positive regulation of molecular function; GO:0055065 metal ion homeostasis; GO:0044770 cell cycle phase transition; GO:0048539 bone marrow development; GO:0002709 regulation of T cell mediated immunity; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0050864 regulation of B cell activation; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0002520 immune system development; GO:0048870 cell motility; GO:0043086 negative regulation of catalytic activity; GO:0051704 multi-organism process; GO:0006874 cellular calcium ion homeostasis; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0098662 inorganic cation transmembrane transport; GO:0044707 single-multicellular organism process; GO:0034220 ion transmembrane transport; GO:0072091 regulation of stem cell proliferation; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0030001 metal ion transport; GO:0001915 negative regulation of T cell mediated cytotoxicity; GO:0048519 negative regulation of biological process; GO:0030098 lymphocyte differentiation; GO:0050867 positive regulation of cell activation; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:2000145 regulation of cell motility; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:2000471 regulation of hematopoietic stem cell migration; GO:0042100 B cell proliferation; GO:0050778 positive regulation of immune response; GO:0030217 T cell differentiation; GO:0048878 chemical homeostasis; GO:0070588 calcium ion transmembrane transport; GO:0051282 regulation of sequestering of calcium ion; GO:0006950 response to stress; GO:0045785 positive regulation of cell adhesion; GO:0051270 regulation of cellular component movement; GO:1902656 calcium ion import into cytosol; GO:0008283 cell proliferation; GO:0002376 immune system process; GO:0002263 cell activation involved in immune response; GO:1903039 positive regulation of leukocyte cell-cell adhesion; GO:1901576 organic substance biosynthetic process; GO:0060348 bone development; GO:0002696 positive regulation of leukocyte activation; GO:0045055 regulated exocytosis; GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration; GO:0031325 positive regulation of cellular metabolic process; GO:0048863 stem cell differentiation; GO:0006955 immune response; GO:0043412 macromolecule modification; GO:0001911 negative regulation of leukocyte mediated cytotoxicity; GO:0045936 negative regulation of phosphate metabolic process; GO:0070838 divalent metal ion transport; GO:0008284 positive regulation of cell proliferation; GO:0051674 localization of cell; GO:0009968 negative regulation of signal transduction; GO:0040017 positive regulation of locomotion; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0031400 negative regulation of protein modification process; GO:0006796 phosphate-containing compound metabolic process; GO:0007165 signal transduction; GO:0009893 positive regulation of metabolic process; GO:0002819 regulation of adaptive immune response; GO:0070663 regulation of leukocyte proliferation; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0050777 negative regulation of immune response; GO:0033674 positive regulation of kinase activity; GO:0060401 cytosolic calcium ion transport; GO:0051726 regulation of cell cycle; GO:0032943 mononuclear cell proliferation; GO:0045937 positive regulation of phosphate metabolic process; GO:0097553 calcium ion transmembrane import into cytosol; GO:0098771 inorganic ion homeostasis; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0050853 B cell receptor signaling pathway; GO:0002820 negative regulation of adaptive immune response; GO:0051607 defense response to virus; GO:0032940 secretion by cell; GO:0070661 leukocyte proliferation; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0070509 calcium ion import; GO:0006952 defense response; GO:0036211 protein modification process; GO:0009615 response to virus; GO:0043549 regulation of kinase activity; GO:0016477 cell migration; GO:0072511 divalent inorganic cation transport; GO:2000021 regulation of ion homeostasis; GO:0042102 positive regulation of T cell proliferation; GO:0060255 regulation of macromolecule metabolic process; GO:0031341 regulation of cell killing; GO:0002704 negative regulation of leukocyte mediated immunity; GO:0001959 regulation of cytokine-mediated signaling pathway; GO:0046651 lymphocyte proliferation; GO:0051707 response to other organism; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:0055080 cation homeostasis; GO:0016032 viral process; GO:0023056 positive regulation of signaling; GO:0002757 immune response-activating signal transduction; GO:0010647 positive regulation of cell communication; GO:0009059 macromolecule biosynthetic process; GO:0035335 peptidyl-tyrosine dephosphorylation; GO:0001932 regulation of protein phosphorylation; GO:0001934 positive regulation of protein phosphorylation; GO:0006470 protein dephosphorylation; GO:0051283 negative regulation of sequestering of calcium ion; GO:0022407 regulation of cell-cell adhesion; GO:0030097 hemopoiesis; GO:0043085 positive regulation of catalytic activity; GO:0002366 leukocyte activation involved in immune response; GO:0002703 regulation of leukocyte mediated immunity; GO:0002710 negative regulation of T cell mediated immunity; GO:0042119 neutrophil activation; GO:0050852 T cell receptor signaling pathway; GO:0002377 immunoglobulin production; GO:0010563 negative regulation of phosphorus metabolic process; GO:0002684 positive regulation of immune system process; GO:0051248 negative regulation of protein metabolic process; GO:0022402 cell cycle process; GO:0007049 cell cycle; GO:0002378 immunoglobulin biosynthetic process; GO:0065008 regulation of biological quality; GO:0030335 positive regulation of cell migration; GO:0032944 regulation of mononuclear cell proliferation; GO:0045321 leukocyte activation; GO:0032270 positive regulation of cellular protein metabolic process; GO:0007166 cell surface receptor signaling pathway; GO:2000648 positive regulation of stem cell proliferation; GO:0009605 response to external stimulus; GO:0032879 regulation of localization; GO:0060402 calcium ion transport into cytosol; GO:0050857 positive regulation of antigen receptor-mediated signaling pathway; GO:0010562 positive regulation of phosphorus metabolic process; GO:0042327 positive regulation of phosphorylation; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0051347 positive regulation of transferase activity; GO:0044419 interspecies interaction between organisms; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0002244 hematopoietic progenitor cell differentiation; GO:0051174 regulation of phosphorus metabolic process; GO:0002443 leukocyte mediated immunity; GO:0050670 regulation of lymphocyte proliferation; GO:0051272 positive regulation of cellular component movement; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0048513 animal organ development; GO:0032269 negative regulation of cellular protein metabolic process; GO:0060759 regulation of response to cytokine stimulus; GO:0050790 regulation of catalytic activity; GO:0010604 positive regulation of macromolecule metabolic process; GO:0002682 regulation of immune system process; GO:0006464 cellular protein modification process; GO:0050794 regulation of cellular process; GO:0007162 negative regulation of cell adhesion; GO:0002283 neutrophil activation involved in immune response; GO:0042127 regulation of cell proliferation; GO:0031399 regulation of protein modification process; GO:0030890 positive regulation of B cell proliferation; GO:0044267 cellular protein metabolic process; GO:0048523 negative regulation of cellular process; GO:2000147 positive regulation of cell motility; GO:0032844 regulation of homeostatic process; GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0051338 regulation of transferase activity; GO:0002707 negative regulation of lymphocyte mediated immunity; GO:0001933 negative regulation of protein phosphorylation; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:0051209 release of sequestered calcium ion into cytosol; GO:2000473 positive regulation of hematopoietic stem cell migration; GO:0002253 activation of immune response; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0031342 negative regulation of cell killing; GO:0030334 regulation of cell migration; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0030155 regulation of cell adhesion; GO:0060761 negative regulation of response to cytokine stimulus; GO:0055085 transmembrane transport; GO:0051247 positive regulation of protein metabolic process; GO:0006873 cellular ion homeostasis; GO:0006793 phosphorus metabolic process; GO:0050870 positive regulation of T cell activation; GO:0006811 ion transport; GO:0006928 movement of cell or subcellular component; GO:0001775 cell activation; GO:0048584 positive regulation of response to stimulus; GO:0007204 positive regulation of cytosolic calcium ion concentration; GO:0051179 localization; GO:0006887 exocytosis; GO:0050863 regulation of T cell activation; GO:0072503 cellular divalent inorganic cation homeostasis; GO:0044764 multi-organism cellular process; GO:0051249 regulation of lymphocyte activation; GO:0051234 establishment of localization; GO:0010646 regulation of cell communication; GO:0050671 positive regulation of lymphocyte proliferation; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0033673 negative regulation of kinase activity; GO:0006929 substrate-dependent cell migration; GO:0002697 regulation of immune effector process; GO:0050851 antigen receptor-mediated signaling pathway; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:0098655 cation transmembrane transport; GO:0009888 tissue development; GO:0050801 ion homeostasis; GO:0002521 leukocyte differentiation; GO:0055074 calcium ion homeostasis; GO:0002446 neutrophil mediated immunity; GO:0048522 positive regulation of cellular process; GO:0019725 cellular homeostasis; GO:0051251 positive regulation of lymphocyte activation; GO:0051348 negative regulation of transferase activity; GO:0002683 negative regulation of immune system process; GO:0050789 regulation of biological process; GO:0050865 regulation of cell activation; GO:0032268 regulation of cellular protein metabolic process; GO:0002440 production of molecular mediator of immune response; GO:0006469 negative regulation of protein kinase activity; GO:0019222 regulation of metabolic process; GO:0040011 locomotion; GO:0019220 regulation of phosphate metabolic process; GO:0043299 leukocyte degranulation; GO:0048856 anatomical structure development; GO:0072507 divalent inorganic cation homeostasis; GO:0001501 skeletal system development; GO:0045859 regulation of protein kinase activity; GO:0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0002252 immune effector process; GO:0051480 regulation of cytosolic calcium ion concentration; GO:0030003 cellular cation homeostasis; GO:0048864 stem cell development; GO:0031324 negative regulation of cellular metabolic process; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0002706 regulation of lymphocyte mediated immunity; GO:0048468 cell development; GO:0055082 cellular chemical homeostasis; GO:0001960 negative regulation of cytokine-mediated signaling pathway; GO:0050854 regulation of antigen receptor-mediated signaling pathway; GO:0001914 regulation of T cell mediated cytotoxicity; GO:0050871 positive regulation of B cell activation; GO:0006816 calcium ion transport; GO:0006812 cation transport; GO:0042326 negative regulation of phosphorylation; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0042113 B cell activation; GO:0001910 regulation of leukocyte mediated cytotoxicity; GO:0022409 positive regulation of cell-cell adhesion; GO:0098660 inorganic ion transmembrane transport; GO:0031401 positive regulation of protein modification process; GO:0046649 lymphocyte activation; GO:0042129 regulation of T cell proliferation; GO:0048585 negative regulation of response to stimulus; GO:0032845 negative regulation of homeostatic process; GO:0045860 positive regulation of protein kinase activity; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0016311 dephosphorylation; GO:0048534 hematopoietic or lymphoid organ development; GO:0051641 cellular localization; GO:0070665 positive regulation of leukocyte proliferation; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0006875 cellular metal ion homeostasis; GO:0009967 positive regulation of signal transduction; GO:0040012 regulation of locomotion; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0009897 external side of plasma membrane; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0098857 membrane microdomain; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0099503 secretory vesicle; GO:0098805 whole membrane; GO:0098589 membrane region; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0030055 cell-substrate junction; GO:0045121 membrane raft; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0098552 side of membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0031226 intrinsic component of plasma membrane; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0030667 secretory granule membrane; GO:0044459 plasma membrane part; GO:0009986 cell surface; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0038023 signaling receptor activity; GO:0016791 phosphatase activity; GO:0019901 protein kinase binding; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0004721 phosphoprotein phosphatase activity; GO:0004888 transmembrane signaling receptor activity; GO:0019900 kinase binding; GO:0004871 signal transducer activity; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0005001 transmembrane receptor protein tyrosine phosphatase activity; GO:0004725 protein tyrosine phosphatase activity; GO:0042578 phosphoric ester hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0019198 transmembrane receptor protein phosphatase activity; GO:0019899 enzyme binding; GO:0099600 transmembrane receptor activity; ","K06478","PTPRC; receptor-type tyrosine-protein phosphatase C [EC:3.1.3.48]","hsa04666 Fc gamma R-mediated phagocytosis - Homo sapiens (human); hsa04660 T cell receptor signaling pathway - Homo sapiens (human); hsa05340 Primary immunodeficiency - Homo sapiens (human); hsa04514 Cell adhesion molecules (CAMs) - Homo sapiens (human); ","IPR029021; IPR024739; IPR000387; IPR003595; IPR013783; IPR000242; IPR003961; ","\"Protein-tyrosine phosphatase-like; Protein tyrosine phosphatase, receptor type, N-terminal; Tyrosine specific protein phosphatases domain; Protein-tyrosine phosphatase, catalytic; Immunoglobulin-like fold; PTP type protein phosphatase; Fibronectin type III; \"\r"]
["P08579","U2 small nuclear ribonucleoprotein B'' OS=Homo sapiens OX=9606 GN=SNRPB2","SNRPB2",25.486,33.834,31.1,7,12,5,0.955,0.979,0.93,1.049,1.044,1.023,1.088,0.00718,"nucleus\r","GO:0006396 RNA processing; GO:0006725 cellular aromatic compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0008152 metabolic process; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0090304 nucleic acid metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0016071 mRNA metabolic process; ","GO:0005685 U1 snRNP; GO:0005686 U2 snRNP; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044452 nucleolar part; GO:0005681 spliceosomal complex; GO:0005730 nucleolus; GO:0001650 fibrillar center; GO:0097525 spliceosomal snRNP complex; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0071013 catalytic step 2 spliceosome; GO:1990904 ribonucleoprotein complex; GO:0030532 small nuclear ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0044428 nuclear part; ","GO:0070990 snRNP binding; GO:0003723 RNA binding; GO:0035613 RNA stem-loop binding; GO:1901265 nucleoside phosphate binding; GO:0044877 macromolecular complex binding; GO:0005515 protein binding; GO:0030619 U1 snRNA binding; GO:0000166 nucleotide binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0043021 ribonucleoprotein complex binding; GO:0017069 snRNA binding; GO:0036094 small molecule binding; GO:0035614 snRNA stem-loop binding; ","K11094","SNRPB2; U2 small nuclear ribonucleoprotein B''","hsa03040 Spliceosome - Homo sapiens (human); ","IPR000504; IPR012677; ","RNA recognition motif domain; Nucleotide-binding alpha-beta plait domain; \r"]
["P08590","Myosin light chain 3 OS=Homo sapiens OX=9606 GN=MYL3","MYL3",21.932,50.19,35.9,6,9,6,0.496,0.556,1.295,1.237,1.213,1.115,1.519,0.233,"cytoplasm\r","GO:0030048 actin filament-based movement; GO:0065008 regulation of biological quality; GO:0070252 actin-mediated cell contraction; GO:0003012 muscle system process; GO:0060415 muscle tissue morphogenesis; GO:0044699 single-organism process; GO:0048729 tissue morphogenesis; GO:0007507 heart development; GO:0044093 positive regulation of molecular function; GO:0003208 cardiac ventricle morphogenesis; GO:0044057 regulation of system process; GO:0007519 skeletal muscle tissue development; GO:0032502 developmental process; GO:0009888 tissue development; GO:0060537 muscle tissue development; GO:0055008 cardiac muscle tissue morphogenesis; GO:0003007 heart morphogenesis; GO:0044763 single-organism cellular process; GO:0006941 striated muscle contraction; GO:0090257 regulation of muscle system process; GO:0060538 skeletal muscle organ development; GO:0032501 multicellular organismal process; GO:0006942 regulation of striated muscle contraction; GO:0048513 animal organ development; GO:0003229 ventricular cardiac muscle tissue development; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:0043462 regulation of ATPase activity; GO:0007517 muscle organ development; GO:0050790 regulation of catalytic activity; GO:0048644 muscle organ morphogenesis; GO:0065009 regulation of molecular function; GO:0009887 animal organ morphogenesis; GO:0032781 positive regulation of ATPase activity; GO:0003015 heart process; GO:0003013 circulatory system process; GO:0048856 anatomical structure development; GO:0014706 striated muscle tissue development; GO:0072359 circulatory system development; GO:0044707 single-multicellular organism process; GO:0030049 muscle filament sliding; GO:0048738 cardiac muscle tissue development; GO:1903522 regulation of blood circulation; GO:0060048 cardiac muscle contraction; GO:0008016 regulation of heart contraction; GO:0051239 regulation of multicellular organismal process; GO:0009653 anatomical structure morphogenesis; GO:0006936 muscle contraction; GO:0055010 ventricular cardiac muscle tissue morphogenesis; GO:0051345 positive regulation of hydrolase activity; GO:0008015 blood circulation; GO:0061061 muscle structure development; GO:0007275 multicellular organism development; GO:0060047 heart contraction; GO:0009987 cellular process; GO:0003231 cardiac ventricle development; GO:0003008 system process; GO:0033275 actin-myosin filament sliding; GO:0048731 system development; GO:0006937 regulation of muscle contraction; GO:0003206 cardiac chamber morphogenesis; GO:0043085 positive regulation of catalytic activity; GO:0003205 cardiac chamber development; GO:0044767 single-organism developmental process; GO:0030029 actin filament-based process; GO:0006928 movement of cell or subcellular component; GO:0002026 regulation of the force of heart contraction; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0030016 myofibril; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0005859 muscle myosin complex; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0099080 supramolecular complex; GO:0031674 I band; GO:0015629 actin cytoskeleton; GO:0044422 organelle part; GO:0099081 supramolecular polymer; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0043226 organelle; GO:0005622 intracellular; GO:0044464 cell part; GO:0031672 A band; GO:0030017 sarcomere; GO:0016460 myosin II complex; GO:0043292 contractile fiber; GO:0044449 contractile fiber part; GO:0043234 protein complex; GO:0016459 myosin complex; GO:0044444 cytoplasmic part; ","GO:0045159 myosin II binding; GO:0003774 motor activity; GO:0032038 myosin II heavy chain binding; GO:0032036 myosin heavy chain binding; GO:0043167 ion binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0017111 nucleoside-triphosphatase activity; GO:0008307 structural constituent of muscle; GO:0008092 cytoskeletal protein binding; GO:0016462 pyrophosphatase activity; GO:0003785 actin monomer binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0003779 actin binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005509 calcium ion binding; GO:0017022 myosin binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005198 structural molecule activity; ","K12749","MYL3; myosin light chain 3","hsa04260 Cardiac muscle contraction - Homo sapiens (human); hsa05414 Dilated cardiomyopathy (DCM) - Homo sapiens (human); hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human); hsa04371 Apelin signaling pathway - Homo sapiens (human); hsa05410 Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human); ","IPR011992; IPR002048; ","EF-hand domain pair; EF-hand domain; \r"]
["P08603","Complement factor H OS=Homo sapiens OX=9606 GN=CFH","CFH",139.09,323.31,44.8,49,98,45,1.023,1.021,1.025,0.996,0.966,0.981,0.959,0.0421,"extracellular\r","GO:0030449 regulation of complement activation; GO:2000257 regulation of protein activation cascade; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0002920 regulation of humoral immune response; GO:0002673 regulation of acute inflammatory response; GO:0006959 humoral immune response; GO:0080134 regulation of response to stress; GO:0050896 response to stimulus; GO:0031347 regulation of defense response; GO:0045087 innate immune response; GO:0071704 organic substance metabolic process; GO:0006956 complement activation; GO:0008152 metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0050778 positive regulation of immune response; GO:0002697 regulation of immune effector process; GO:0010468 regulation of gene expression; GO:0002253 activation of immune response; GO:0006950 response to stress; GO:0080090 regulation of primary metabolic process; GO:0032101 regulation of response to external stimulus; GO:0072376 protein activation cascade; GO:0002376 immune system process; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0050776 regulation of immune response; GO:0050789 regulation of biological process; GO:0006957 complement activation, alternative pathway; GO:0051246 regulation of protein metabolic process; GO:0002684 positive regulation of immune system process; GO:0048583 regulation of response to stimulus; GO:0070613 regulation of protein processing; GO:0050727 regulation of inflammatory response; GO:0019222 regulation of metabolic process; GO:0002682 regulation of immune system process; GO:0006952 defense response; GO:1903317 regulation of protein maturation; GO:0006955 immune response; GO:0048584 positive regulation of response to stimulus; GO:0065007 biological regulation; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0072562 blood microparticle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:0097367 carbohydrate derivative binding; GO:0005488 binding; GO:0043167 ion binding; GO:0043394 proteoglycan binding; GO:0043395 heparan sulfate proteoglycan binding; GO:0043168 anion binding; GO:0005515 protein binding; GO:0008201 heparin binding; GO:0005539 glycosaminoglycan binding; GO:0001948 glycoprotein binding; GO:1901681 sulfur compound binding; ","K04004","CFH; complement factor H","hsa04610 Complement and coagulation cascades - Homo sapiens (human); hsa05150 Staphylococcus aureus infection - Homo sapiens (human); ","IPR000436; ","Sushi/SCR/CCP domain; \r"]
["P08621","U1 small nuclear ribonucleoprotein 70 kDa OS=Homo sapiens OX=9606 GN=SNRNP70","SNRNP70",51.556,22.1,16,7,11,7,0.918,0.917,0.9,1.033,1.127,1.077,1.184,0.00294,"nucleus\r","GO:0001101 response to acid chemical; GO:0071560 cellular response to transforming growth factor beta stimulus; GO:0071363 cellular response to growth factor stimulus; GO:0044237 cellular metabolic process; GO:0071345 cellular response to cytokine stimulus; GO:0008152 metabolic process; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0071300 cellular response to retinoic acid; GO:0009719 response to endogenous stimulus; GO:0070848 response to growth factor; GO:0043170 macromolecule metabolic process; GO:0034612 response to tumor necrosis factor; GO:0048024 regulation of mRNA splicing, via spliceosome; GO:0070887 cellular response to chemical stimulus; GO:0006396 RNA processing; GO:0010468 regulation of gene expression; GO:0051716 cellular response to stimulus; GO:0034097 response to cytokine; GO:0080090 regulation of primary metabolic process; GO:0061084 negative regulation of protein refolding; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0061083 regulation of protein refolding; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0050684 regulation of mRNA processing; GO:0031323 regulation of cellular metabolic process; GO:0071559 response to transforming growth factor beta; GO:0010506 regulation of autophagy; GO:0010605 negative regulation of macromolecule metabolic process; GO:1903313 positive regulation of mRNA metabolic process; GO:0071396 cellular response to lipid; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:1904715 negative regulation of chaperone-mediated autophagy; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0051336 regulation of hydrolase activity; GO:0090304 nucleic acid metabolic process; GO:0043462 regulation of ATPase activity; GO:0032526 response to retinoic acid; GO:0050790 regulation of catalytic activity; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0010507 negative regulation of autophagy; GO:0016071 mRNA metabolic process; GO:1903332 regulation of protein folding; GO:0033120 positive regulation of RNA splicing; GO:0050794 regulation of cellular process; GO:0050685 positive regulation of mRNA processing; GO:0042177 negative regulation of protein catabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0071356 cellular response to tumor necrosis factor; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:1901700 response to oxygen-containing compound; GO:1903333 negative regulation of protein folding; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0033993 response to lipid; GO:0000398 mRNA splicing, via spliceosome; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0071229 cellular response to acid chemical; GO:0006139 nucleobase-containing compound metabolic process; GO:0010628 positive regulation of gene expression; GO:0000375 RNA splicing, via transesterification reactions; GO:0051171 regulation of nitrogen compound metabolic process; GO:0009895 negative regulation of catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0042176 regulation of protein catabolic process; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0051254 positive regulation of RNA metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0010033 response to organic substance; GO:1904714 regulation of chaperone-mediated autophagy; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0009892 negative regulation of metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0043484 regulation of RNA splicing; GO:0031330 negative regulation of cellular catabolic process; GO:1903311 regulation of mRNA metabolic process; GO:1901701 cellular response to oxygen-containing compound; GO:0071495 cellular response to endogenous stimulus; GO:0051246 regulation of protein metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0048026 positive regulation of mRNA splicing, via spliceosome; GO:0051248 negative regulation of protein metabolic process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0010467 gene expression; GO:0065007 biological regulation; ","GO:0005685 U1 snRNP; GO:0005737 cytoplasm; GO:0005684 U2-type spliceosomal complex; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0071011 precatalytic spliceosome; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0044464 cell part; GO:0005622 intracellular; GO:0071004 U2-type prespliceosome; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0000243 commitment complex; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005681 spliceosomal complex; GO:0097525 spliceosomal snRNP complex; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0071010 prespliceosome; GO:1990904 ribonucleoprotein complex; GO:0030532 small nuclear ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0044428 nuclear part; ","GO:0070990 snRNP binding; GO:0003723 RNA binding; GO:1901265 nucleoside phosphate binding; GO:0044877 macromolecular complex binding; GO:0005515 protein binding; GO:0030619 U1 snRNA binding; GO:0000166 nucleotide binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0003729 mRNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0017069 snRNA binding; GO:0043021 ribonucleoprotein complex binding; GO:1990446 U1 snRNP binding; GO:0036094 small molecule binding; ","K11093","SNRP70; U1 small nuclear ribonucleoprotein 70kDa","hsa03040 Spliceosome - Homo sapiens (human); ","IPR022023; IPR034143; IPR000504; IPR012677; ","\"U1 small nuclear ribonucleoprotein of 70kDa N-terminal; snRNP70, RNA recognition motif; RNA recognition motif domain; Nucleotide-binding alpha-beta plait domain; \"\r"]
["P08648","Integrin alpha-5 OS=Homo sapiens OX=9606 GN=ITGA5","ITGA5",114.54,18.167,6.2,6,9,6,1.042,1.047,1.105,0.985,0.99,0.908,0.903,0.0381,"nucleus\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0044409 entry into host; GO:0010941 regulation of cell death; GO:0030335 positive regulation of cell migration; GO:0032270 positive regulation of cellular protein metabolic process; GO:0007166 cell surface receptor signaling pathway; GO:0050877 neurological system process; GO:0007610 behavior; GO:0007492 endoderm development; GO:0022610 biological adhesion; GO:0001525 angiogenesis; GO:0051240 positive regulation of multicellular organismal process; GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; GO:0032879 regulation of localization; GO:1904018 positive regulation of vasculature development; GO:0007155 cell adhesion; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0009790 embryo development; GO:0044419 interspecies interaction between organisms; GO:0048598 embryonic morphogenesis; GO:0046718 viral entry into host cell; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:0090504 epiboly; GO:0044763 single-organism cellular process; GO:0090287 regulation of cellular response to growth factor stimulus; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0048870 cell motility; GO:0051272 positive regulation of cellular component movement; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0010811 positive regulation of cell-substrate adhesion; GO:0051704 multi-organism process; GO:0050900 leukocyte migration; GO:0048583 regulation of response to stimulus; GO:0098602 single organism cell adhesion; GO:0010604 positive regulation of macromolecule metabolic process; GO:0045765 regulation of angiogenesis; GO:0033631 cell-cell adhesion mediated by integrin; GO:0051094 positive regulation of developmental process; GO:0060548 negative regulation of cell death; GO:0044708 single-organism behavior; GO:0050794 regulation of cellular process; GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation; GO:0072359 circulatory system development; GO:0002009 morphogenesis of an epithelium; GO:0044707 single-multicellular organism process; GO:0051806 entry into cell of other organism involved in symbiotic interaction; GO:0031399 regulation of protein modification process; GO:0043067 regulation of programmed cell death; GO:2000209 regulation of anoikis; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:2000147 positive regulation of cell motility; GO:0051239 regulation of multicellular organismal process; GO:0009653 anatomical structure morphogenesis; GO:0043062 extracellular structure organization; GO:2000145 regulation of cell motility; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0006950 response to stress; GO:0045785 positive regulation of cell adhesion; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0002376 immune system process; GO:0030334 regulation of cell migration; GO:0072358 cardiovascular system development; GO:0030155 regulation of cell adhesion; GO:0051247 positive regulation of protein metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0006928 movement of cell or subcellular component; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0010810 regulation of cell-substrate adhesion; GO:0050793 regulation of developmental process; GO:0051674 localization of cell; GO:0001568 blood vessel development; GO:0040017 positive regulation of locomotion; GO:0033627 cell adhesion mediated by integrin; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0034113 heterotypic cell-cell adhesion; GO:0009611 response to wounding; GO:0048729 tissue morphogenesis; GO:0016337 single organismal cell-cell adhesion; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0022607 cellular component assembly; GO:0048514 blood vessel morphogenesis; GO:0030198 extracellular matrix organization; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0007044 cell-substrate junction assembly; GO:0045937 positive regulation of phosphate metabolic process; GO:0009888 tissue development; GO:0090505 epiboly involved in wound healing; GO:0001704 formation of primary germ layer; GO:0098609 cell-cell adhesion; GO:0048522 positive regulation of cellular process; GO:0001944 vasculature development; GO:0023052 signaling; GO:0007229 integrin-mediated signaling pathway; GO:0044319 wound healing, spreading of cells; GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway; GO:0030260 entry into host cell; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0051828 entry into other organism involved in symbiotic interaction; GO:2000811 negative regulation of anoikis; GO:0007613 memory; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0040011 locomotion; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:1903670 regulation of sprouting angiogenesis; GO:0016043 cellular component organization; GO:0034329 cell junction assembly; GO:0016477 cell migration; GO:0007159 leukocyte cell-cell adhesion; GO:0043069 negative regulation of programmed cell death; GO:0050730 regulation of peptidyl-tyrosine phosphorylation; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0050896 response to stimulus; GO:0045766 positive regulation of angiogenesis; GO:0007369 gastrulation; GO:0030154 cell differentiation; GO:0043066 negative regulation of apoptotic process; GO:0016032 viral process; GO:0023056 positive regulation of signaling; GO:0050890 cognition; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:0003008 system process; GO:0001706 endoderm formation; GO:0035987 endodermal cell differentiation; GO:0002011 morphogenesis of an epithelial sheet; GO:1901342 regulation of vasculature development; GO:0001932 regulation of protein phosphorylation; GO:0031401 positive regulation of protein modification process; GO:0001934 positive regulation of protein phosphorylation; GO:0051701 interaction with host; GO:0048518 positive regulation of biological process; GO:0007611 learning or memory; GO:0042060 wound healing; GO:0034330 cell junction organization; GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway; GO:0031589 cell-substrate adhesion; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:1903672 positive regulation of sprouting angiogenesis; GO:0035313 wound healing, spreading of epidermal cells; GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules; GO:0009967 positive regulation of signal transduction; GO:0040012 regulation of locomotion; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0098636 protein complex involved in cell adhesion; GO:0005783 endoplasmic reticulum; GO:0009897 external side of plasma membrane; GO:0031410 cytoplasmic vesicle; GO:0098796 membrane protein complex; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0005925 focal adhesion; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0098552 side of membrane; GO:0031252 cell leading edge; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0042995 cell projection; GO:0031226 intrinsic component of plasma membrane; GO:0098797 plasma membrane protein complex; GO:0098802 plasma membrane receptor complex; GO:0043235 receptor complex; GO:0070161 anchoring junction; GO:0008305 integrin complex; GO:0012505 endomembrane system; GO:0016021 integral component of membrane; GO:0045202 synapse; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044459 plasma membrane part; GO:0001726 ruffle; GO:0009986 cell surface; GO:0005794 Golgi apparatus; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0071062 alphav-beta3 integrin-vitronectin complex; ","GO:0005102 receptor binding; GO:0043167 ion binding; GO:0005126 cytokine receptor binding; GO:0044877 macromolecular complex binding; GO:0070851 growth factor receptor binding; GO:0005172 vascular endothelial growth factor receptor binding; GO:0005515 protein binding; GO:0005178 integrin binding; GO:0001618 virus receptor activity; GO:0050839 cell adhesion molecule binding; GO:0005161 platelet-derived growth factor receptor binding; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0005154 epidermal growth factor receptor binding; GO:0005488 binding; GO:0043184 vascular endothelial growth factor receptor 2 binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0032403 protein complex binding; ","K06484","ITGA5; integrin alpha 5","hsa05100 Bacterial invasion of epithelial cells - Homo sapiens (human); hsa05414 Dilated cardiomyopathy (DCM) - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa04640 Hematopoietic cell lineage - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa05133 Pertussis - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa05206 MicroRNAs in cancer - Homo sapiens (human); hsa04512 ECM-receptor interaction - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); hsa05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human); hsa05131 Shigellosis - Homo sapiens (human); hsa05410 Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human); ","IPR032695; IPR013649; ","Integrin domain; Integrin alpha-2; \r"]
["P08651","Nuclear factor 1 C-type OS=Homo sapiens OX=9606 GN=NFIC","NFIC",55.674,11.747,8.9,4,5,3,0.974,0.966,1.066,0.943,0.997,1.064,0.999,0.986,"nucleus\r","GO:0097659 nucleic acid-templated transcription; GO:0009891 positive regulation of biosynthetic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0051253 negative regulation of RNA metabolic process; GO:0044237 cellular metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0042475 odontogenesis of dentin-containing tooth; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0043170 macromolecule metabolic process; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0000122 negative regulation of transcription from RNA polymerase II promoter; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0042476 odontogenesis; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:1902679 negative regulation of RNA biosynthetic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0009887 animal organ morphogenesis; GO:0019222 regulation of metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0048856 anatomical structure development; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0006260 DNA replication; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0006259 DNA metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0071704 organic substance metabolic process; GO:0045892 negative regulation of transcription, DNA-templated; GO:0009653 anatomical structure morphogenesis; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0051254 positive regulation of RNA metabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0048731 system development; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:1901576 organic substance biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0009892 negative regulation of metabolic process; GO:0044249 cellular biosynthetic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0009890 negative regulation of biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0044767 single-organism developmental process; GO:0031325 positive regulation of cellular metabolic process; GO:0006366 transcription from RNA polymerase II promoter; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0010467 gene expression; GO:0031327 negative regulation of cellular biosynthetic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0044452 nucleolar part; GO:0005730 nucleolus; GO:0005623 cell; GO:0001650 fibrillar center; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding; GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding; GO:0003677 DNA binding; GO:0000976 transcription regulatory region sequence-specific DNA binding; GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding; GO:0003690 double-stranded DNA binding; GO:1990837 sequence-specific double-stranded DNA binding; GO:0001012 RNA polymerase II regulatory region DNA binding; GO:0043565 sequence-specific DNA binding; GO:0000987 core promoter proximal region sequence-specific DNA binding; GO:0003700 transcription factor activity, sequence-specific DNA binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0000975 regulatory region DNA binding; GO:0001159 core promoter proximal region DNA binding; GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding; GO:0001067 regulatory region nucleic acid binding; GO:0005488 binding; GO:0044212 transcription regulatory region DNA binding; GO:0003676 nucleic acid binding; GO:0001071 nucleic acid binding transcription factor activity; GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding; GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding; ","K09170",null,null,"IPR019548; IPR003619; IPR020604; ","\"CTF transcription factor/nuclear factor 1, N-terminal; MAD homology 1, Dwarfin-type; CTF transcription factor/nuclear factor 1, DNA-binding domain; \"\r"]
["P08670","Vimentin OS=Homo sapiens OX=9606 GN=VIM","VIM",53.651,323.31,75.3,43,212,35,1.137,1.142,1.112,0.857,0.893,0.873,0.774,5.96e-05,"nucleus\r","GO:0044700 single organism signaling; GO:0030048 actin filament-based movement; GO:0051093 negative regulation of developmental process; GO:0070252 actin-mediated cell contraction; GO:0003012 muscle system process; GO:0045109 intermediate filament organization; GO:0007166 cell surface receptor signaling pathway; GO:0051129 negative regulation of cellular component organization; GO:0048869 cellular developmental process; GO:0070306 lens fiber cell differentiation; GO:0051241 negative regulation of multicellular organismal process; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0060020 Bergmann glial cell differentiation; GO:0002088 lens development in camera-type eye; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0009893 positive regulation of metabolic process; GO:0045596 negative regulation of cell differentiation; GO:0044419 interspecies interaction between organisms; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0060429 epithelium development; GO:0010468 regulation of gene expression; GO:0002064 epithelial cell development; GO:0009888 tissue development; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0023052 signaling; GO:0070307 lens fiber cell development; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0050768 negative regulation of neurogenesis; GO:1902589 single-organism organelle organization; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0042063 gliogenesis; GO:0045664 regulation of neuron differentiation; GO:0007417 central nervous system development; GO:0060395 SMAD protein signal transduction; GO:0045665 negative regulation of neuron differentiation; GO:0021782 glial cell development; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0048708 astrocyte differentiation; GO:0010721 negative regulation of cell development; GO:0048856 anatomical structure development; GO:0097435 supramolecular fiber organization; GO:0010975 regulation of neuron projection development; GO:0030855 epithelial cell differentiation; GO:2000026 regulation of multicellular organismal development; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0043010 camera-type eye development; GO:0030049 muscle filament sliding; GO:0060255 regulation of macromolecule metabolic process; GO:0014002 astrocyte development; GO:0031344 regulation of cell projection organization; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0051239 regulation of multicellular organismal process; GO:0001654 eye development; GO:0030154 cell differentiation; GO:0006936 muscle contraction; GO:0051961 negative regulation of nervous system development; GO:0016032 viral process; GO:0010628 positive regulation of gene expression; GO:0031345 negative regulation of cell projection organization; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0003008 system process; GO:0045104 intermediate filament cytoskeleton organization; GO:0033275 actin-myosin filament sliding; GO:0048731 system development; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0045103 intermediate filament-based process; GO:0010977 negative regulation of neuron projection development; GO:0048518 positive regulation of biological process; GO:0010001 glial cell differentiation; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0030029 actin filament-based process; GO:0006928 movement of cell or subcellular component; GO:0051128 regulation of cellular component organization; GO:0007423 sensory organ development; GO:0050793 regulation of developmental process; GO:0050767 regulation of neurogenesis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005856 cytoskeleton; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0044464 cell part; GO:0042579 microbody; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0005924 cell-substrate adherens junction; GO:0043229 intracellular organelle; GO:0031252 cell leading edge; GO:0099513 polymeric cytoskeletal fiber; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0005777 peroxisome; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0099081 supramolecular polymer; GO:0005886 plasma membrane; GO:0031012 extracellular matrix; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0045111 intermediate filament cytoskeleton; GO:0005882 intermediate filament; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005212 structural constituent of eye lens; GO:0003723 RNA binding; GO:0003725 double-stranded RNA binding; GO:0044877 macromolecular complex binding; GO:0097110 scaffold protein binding; GO:0005515 protein binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0097367 carbohydrate derivative binding; GO:0042802 identical protein binding; GO:0005200 structural constituent of cytoskeleton; GO:0019215 intermediate filament binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0008022 protein C-terminus binding; GO:1990254 keratin filament binding; GO:0001948 glycoprotein binding; GO:0005198 structural molecule activity; GO:0032403 protein complex binding; ","K07606","VIM; vimentin","hsa05206 MicroRNAs in cancer - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); ","IPR006821; ","\"Intermediate filament head, DNA-binding domain; \"\r"]
["P08697","Alpha-2-antiplasmin OS=Homo sapiens OX=9606 GN=SERPINF2","SERPINF2",54.565,123.93,24.2,12,17,12,1.018,1.013,0.994,0.985,0.98,1.033,0.991,0.641,"extracellular\r","GO:0065008 regulation of biological quality; GO:0032872 regulation of stress-activated MAPK cascade; GO:0032270 positive regulation of cellular protein metabolic process; GO:0030199 collagen fibril organization; GO:1903318 negative regulation of protein maturation; GO:0009891 positive regulation of biosynthetic process; GO:0002034 regulation of blood vessel diameter by renin-angiotensin; GO:0042730 fibrinolysis; GO:0010466 negative regulation of peptidase activity; GO:0051240 positive regulation of multicellular organismal process; GO:0032102 negative regulation of response to external stimulus; GO:2000047 regulation of cell-cell adhesion mediated by cadherin; GO:0090303 positive regulation of wound healing; GO:0010562 positive regulation of phosphorus metabolic process; GO:0042327 positive regulation of phosphorylation; GO:0051493 regulation of cytoskeleton organization; GO:0030194 positive regulation of blood coagulation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0003044 regulation of systemic arterial blood pressure mediated by a chemical signal; GO:0052548 regulation of endopeptidase activity; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0001990 regulation of systemic arterial blood pressure by hormone; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044763 single-organism cellular process; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0035296 regulation of tube diameter; GO:0006810 transport; GO:1903506 regulation of nucleic acid-templated transcription; GO:0006953 acute-phase response; GO:0051336 regulation of hydrolase activity; GO:0080135 regulation of cellular response to stress; GO:1900048 positive regulation of hemostasis; GO:0032874 positive regulation of stress-activated MAPK cascade; GO:0002526 acute inflammatory response; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:1902905 positive regulation of supramolecular fiber organization; GO:0032233 positive regulation of actin filament bundle assembly; GO:1903317 regulation of protein maturation; GO:0003013 circulatory system process; GO:0010755 regulation of plasminogen activation; GO:0051094 positive regulation of developmental process; GO:0097435 supramolecular fiber organization; GO:1902903 regulation of supramolecular fiber organization; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:1903036 positive regulation of response to wounding; GO:0072359 circulatory system development; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0010951 negative regulation of endopeptidase activity; GO:0042127 regulation of cell proliferation; GO:0050880 regulation of blood vessel size; GO:0001819 positive regulation of cytokine production; GO:0032956 regulation of actin cytoskeleton organization; GO:0031399 regulation of protein modification process; GO:0010955 negative regulation of protein processing; GO:0030193 regulation of blood coagulation; GO:0002576 platelet degranulation; GO:0003018 vascular process in circulatory system; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0045597 positive regulation of cell differentiation; GO:0051239 regulation of multicellular organismal process; GO:1900047 negative regulation of hemostasis; GO:0009653 anatomical structure morphogenesis; GO:0070372 regulation of ERK1 and ERK2 cascade; GO:1902578 single-organism localization; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0043062 extracellular structure organization; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0044253 positive regulation of multicellular organismal metabolic process; GO:0007275 multicellular organism development; GO:0035150 regulation of tube size; GO:0009966 regulation of signal transduction; GO:0051254 positive regulation of RNA metabolic process; GO:0045861 negative regulation of proteolysis; GO:0071634 regulation of transforming growth factor beta production; GO:1902531 regulation of intracellular signal transduction; GO:0051495 positive regulation of cytoskeleton organization; GO:0045785 positive regulation of cell adhesion; GO:0006950 response to stress; GO:0032231 regulation of actin filament bundle assembly; GO:0048731 system development; GO:0003014 renal system process; GO:0016192 vesicle-mediated transport; GO:0051917 regulation of fibrinolysis; GO:0032970 regulation of actin filament-based process; GO:0072358 cardiovascular system development; GO:0032101 regulation of response to external stimulus; GO:0010033 response to organic substance; GO:0030162 regulation of proteolysis; GO:0009892 negative regulation of metabolic process; GO:0030155 regulation of cell adhesion; GO:0051492 regulation of stress fiber assembly; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0030195 negative regulation of blood coagulation; GO:0032965 regulation of collagen biosynthetic process; GO:0045055 regulated exocytosis; GO:0051247 positive regulation of protein metabolic process; GO:0010757 negative regulation of plasminogen activation; GO:0061041 regulation of wound healing; GO:0031325 positive regulation of cellular metabolic process; GO:0070613 regulation of protein processing; GO:0051496 positive regulation of stress fiber assembly; GO:0048661 positive regulation of smooth muscle cell proliferation; GO:0031328 positive regulation of cellular biosynthetic process; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:0050793 regulation of developmental process; GO:0003071 renal system process involved in regulation of systemic arterial blood pressure; GO:1903034 regulation of response to wounding; GO:0010712 regulation of collagen metabolic process; GO:0050819 negative regulation of coagulation; GO:0008284 positive regulation of cell proliferation; GO:0006887 exocytosis; GO:0046330 positive regulation of JNK cascade; GO:0044246 regulation of multicellular organismal metabolic process; GO:0001568 blood vessel development; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0097746 regulation of blood vessel diameter; GO:2001141 regulation of RNA biosynthetic process; GO:0010646 regulation of cell communication; GO:0070302 regulation of stress-activated protein kinase signaling cascade; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0070304 positive regulation of stress-activated protein kinase signaling cascade; GO:0032103 positive regulation of response to external stimulus; GO:1900046 regulation of hemostasis; GO:0003073 regulation of systemic arterial blood pressure; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0048514 blood vessel morphogenesis; GO:0030198 extracellular matrix organization; GO:0046328 regulation of JNK cascade; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0045937 positive regulation of phosphate metabolic process; GO:0071822 protein complex subunit organization; GO:0031326 regulation of cellular biosynthetic process; GO:0050886 endocrine process; GO:0001944 vasculature development; GO:0048522 positive regulation of cellular process; GO:0010605 negative regulation of macromolecule metabolic process; GO:1903035 negative regulation of response to wounding; GO:0003072 renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0010638 positive regulation of organelle organization; GO:0010714 positive regulation of collagen metabolic process; GO:0032940 secretion by cell; GO:0006954 inflammatory response; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0006952 defense response; GO:0019220 regulation of phosphate metabolic process; GO:0052547 regulation of peptidase activity; GO:0048856 anatomical structure development; GO:0008217 regulation of blood pressure; GO:0016043 cellular component organization; GO:0048660 regulation of smooth muscle cell proliferation; GO:0060255 regulation of macromolecule metabolic process; GO:0032967 positive regulation of collagen biosynthetic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0051918 negative regulation of fibrinolysis; GO:0044087 regulation of cellular component biogenesis; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0051346 negative regulation of hydrolase activity; GO:0043408 regulation of MAPK cascade; GO:0023056 positive regulation of signaling; GO:0008015 blood circulation; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0006355 regulation of transcription, DNA-templated; GO:0050878 regulation of body fluid levels; GO:0003008 system process; GO:0022409 positive regulation of cell-cell adhesion; GO:0010629 negative regulation of gene expression; GO:0001932 regulation of protein phosphorylation; GO:0033043 regulation of organelle organization; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0031401 positive regulation of protein modification process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0050820 positive regulation of coagulation; GO:0001934 positive regulation of protein phosphorylation; GO:0051252 regulation of RNA metabolic process; GO:0061045 negative regulation of wound healing; GO:0048518 positive regulation of biological process; GO:0022407 regulation of cell-cell adhesion; GO:0043933 macromolecular complex subunit organization; GO:0050818 regulation of coagulation; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin; GO:0001817 regulation of cytokine production; GO:0090066 regulation of anatomical structure size; GO:0051248 negative regulation of protein metabolic process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0051128 regulation of cellular component organization; GO:0009967 positive regulation of signal transduction; GO:0071636 positive regulation of transforming growth factor beta production; GO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin; GO:0043410 positive regulation of MAPK cascade; GO:0070374 positive regulation of ERK1 and ERK2 cascade; GO:0044089 positive regulation of cellular component biogenesis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0034774 secretory granule lumen; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0005577 fibrinogen complex; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0043226 organelle; GO:0072562 blood microparticle; GO:0060205 cytoplasmic vesicle lumen; GO:0031093 platelet alpha granule lumen; GO:0009986 cell surface; GO:0031091 platelet alpha granule; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0046983 protein dimerization activity; GO:0061134 peptidase regulator activity; GO:0005515 protein binding; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0004866 endopeptidase inhibitor activity; GO:0002020 protease binding; GO:0004867 serine-type endopeptidase inhibitor activity; GO:0042802 identical protein binding; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0042803 protein homodimerization activity; GO:0030414 peptidase inhibitor activity; GO:0061135 endopeptidase regulator activity; GO:0019899 enzyme binding; ","K03983","SERPINF2; alpha-2-antiplasmin","hsa04610 Complement and coagulation cascades - Homo sapiens (human); ","IPR033833; IPR023796; ","Alpha2-antiplasmin; Serpin domain; \r"]
["P08708","40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17","RPS17",15.55,49.478,45.2,7,10,7,0.747,0.78,0.755,1.283,1.239,1.155,1.611,0.000141,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0022613 ribonucleoprotein complex biogenesis; GO:0072594 establishment of protein localization to organelle; GO:0006518 peptide metabolic process; GO:0022618 ribonucleoprotein complex assembly; GO:0002262 myeloid cell homeostasis; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0034101 erythrocyte homeostasis; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0051649 establishment of localization in cell; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0071826 ribonucleoprotein complex subunit organization; GO:0070972 protein localization to endoplasmic reticulum; GO:0022607 cellular component assembly; GO:0006364 rRNA processing; GO:0065003 macromolecular complex assembly; GO:0006413 translational initiation; GO:1901361 organic cyclic compound catabolic process; GO:0033365 protein localization to organelle; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0006412 translation; GO:0016072 rRNA metabolic process; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0072657 protein localization to membrane; GO:0043043 peptide biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0042254 ribosome biogenesis; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032774 RNA biosynthetic process; GO:0045047 protein targeting to ER; GO:0043603 cellular amide metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0016070 RNA metabolic process; GO:0006401 RNA catabolic process; GO:0048872 homeostasis of number of cells; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0019083 viral transcription; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0044267 cellular protein metabolic process; GO:0006613 cotranslational protein targeting to membrane; GO:0048519 negative regulation of biological process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0070925 organelle assembly; GO:0006139 nucleobase-containing compound metabolic process; GO:0016032 viral process; GO:0019080 viral gene expression; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0006886 intracellular protein transport; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0034613 cellular protein localization; GO:0009059 macromolecule biosynthetic process; GO:0090150 establishment of protein localization to membrane; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0034622 cellular macromolecular complex assembly; GO:0044265 cellular macromolecule catabolic process; GO:0042274 ribosomal small subunit biogenesis; GO:0010629 negative regulation of gene expression; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0000028 ribosomal small subunit assembly; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0043933 macromolecular complex subunit organization; GO:0042255 ribosome assembly; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006996 organelle organization; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0051179 localization; GO:0034660 ncRNA metabolic process; GO:0009056 catabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; GO:0046700 heterocycle catabolic process; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0030054 cell junction; GO:0015935 small ribosomal subunit; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0005925 focal adhesion; GO:0070013 intracellular organelle lumen; GO:0044391 ribosomal subunit; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0044445 cytosolic part; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0022626 cytosolic ribosome; GO:0043229 intracellular organelle; GO:0005840 ribosome; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0031012 extracellular matrix; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0022627 cytosolic small ribosomal subunit; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005198 structural molecule activity; GO:0003735 structural constituent of ribosome; ","K02962","RP-S17e; small subunit ribosomal protein S17e","hsa03010 Ribosome - Homo sapiens (human); "]
["P08754","Guanine nucleotide-binding protein G(k) subunit alpha OS=Homo sapiens OX=9606 GN=GNAI3","GNAI3",40.532,7.6969,23.4,8,17,1,0.992,0.899,1.008,1.006,1.042,1.053,1.07,0.149,"cytoplasm\r","GO:0044700 single organism signaling; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:1900372 negative regulation of purine nucleotide biosynthetic process; GO:0030815 negative regulation of cAMP metabolic process; GO:0045980 negative regulation of nucleotide metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0006457 protein folding; GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:1901068 guanosine-containing compound metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0030814 regulation of cAMP metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0044801 single-organism membrane fusion; GO:0030808 regulation of nucleotide biosynthetic process; GO:0051716 cellular response to stimulus; GO:0051174 regulation of phosphorus metabolic process; GO:0030802 regulation of cyclic nucleotide biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0044281 small molecule metabolic process; GO:0007212 dopamine receptor signaling pathway; GO:0044763 single-organism cellular process; GO:0072521 purine-containing compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0061025 membrane fusion; GO:0031323 regulation of cellular metabolic process; GO:0043086 negative regulation of catalytic activity; GO:0023052 signaling; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway; GO:0006810 transport; GO:0051339 regulation of lyase activity; GO:1902589 single-organism organelle organization; GO:0031279 regulation of cyclase activity; GO:0050789 regulation of biological process; GO:0044710 single-organism metabolic process; GO:1900371 regulation of purine nucleotide biosynthetic process; GO:0050790 regulation of catalytic activity; GO:0006906 vesicle fusion; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0030809 negative regulation of nucleotide biosynthetic process; GO:0044092 negative regulation of molecular function; GO:1901657 glycosyl compound metabolic process; GO:0051301 cell division; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0046039 GTP metabolic process; GO:0006140 regulation of nucleotide metabolic process; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0090174 organelle membrane fusion; GO:0006725 cellular aromatic compound metabolic process; GO:0009259 ribonucleotide metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0030803 negative regulation of cyclic nucleotide biosynthetic process; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:0045761 regulation of adenylate cyclase activity; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0030817 regulation of cAMP biosynthetic process; GO:1901135 carbohydrate derivative metabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0009119 ribonucleoside metabolic process; GO:0009987 cellular process; GO:0031280 negative regulation of cyclase activity; GO:0016192 vesicle-mediated transport; GO:0051350 negative regulation of lyase activity; GO:0006807 nitrogen compound metabolic process; GO:0044802 single-organism membrane organization; GO:0016050 vesicle organization; GO:0009141 nucleoside triphosphate metabolic process; GO:0048284 organelle fusion; GO:0030800 negative regulation of cyclic nucleotide metabolic process; GO:0007194 negative regulation of adenylate cyclase activity; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0044238 primary metabolic process; GO:0030799 regulation of cyclic nucleotide metabolic process; GO:0009892 negative regulation of metabolic process; GO:0006163 purine nucleotide metabolic process; GO:0030818 negative regulation of cAMP biosynthetic process; GO:0007186 G-protein coupled receptor signaling pathway; GO:1900542 regulation of purine nucleotide metabolic process; GO:0046128 purine ribonucleoside metabolic process; GO:0009890 negative regulation of biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:1900543 negative regulation of purine nucleotide metabolic process; GO:0010563 negative regulation of phosphorus metabolic process; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0051179 localization; GO:0007049 cell cycle; GO:0045936 negative regulation of phosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0019898 extrinsic component of membrane; GO:0031090 organelle membrane; GO:0098857 membrane microdomain; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0005623 cell; GO:0009898 cytoplasmic side of plasma membrane; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005765 lysosomal membrane; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:0098589 membrane region; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0098552 side of membrane; GO:0000323 lytic vacuole; GO:1905360 GTPase complex; GO:0044430 cytoskeletal part; GO:0098797 plasma membrane protein complex; GO:0030496 midbody; GO:0019897 extrinsic component of plasma membrane; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0031410 cytoplasmic vesicle; GO:0042588 zymogen granule; GO:0098796 membrane protein complex; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0031234 extrinsic component of cytoplasmic side of plasma membrane; GO:0098562 cytoplasmic side of membrane; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0005815 microtubule organizing center; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0005834 heterotrimeric G-protein complex; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0045121 membrane raft; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0005813 centrosome; GO:0005774 vacuolar membrane; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0005102 receptor binding; GO:0031683 G-protein beta/gamma-subunit complex binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0004871 signal transducer activity; GO:0032794 GTPase activating protein binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0019003 GDP binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0003924 GTPase activity; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0001664 G-protein coupled receptor binding; GO:0043168 anion binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0017076 purine nucleotide binding; GO:0031821 G-protein coupled serotonin receptor binding; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0046872 metal ion binding; GO:0019904 protein domain specific binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0032561 guanyl ribonucleotide binding; GO:0032403 protein complex binding; GO:0036094 small molecule binding; ","K04630","GNAI; guanine nucleotide-binding protein G(i) subunit alpha","hsa04015 Rap1 signaling pathway - Homo sapiens (human); hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human); hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human); hsa04924 Renin secretion - Homo sapiens (human); hsa04724 Glutamatergic synapse - Homo sapiens (human); hsa05145 Toxoplasmosis - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa04934 Cushing's syndrome - Homo sapiens (human); hsa04071 Sphingolipid signaling pathway - Homo sapiens (human); hsa04611 Platelet activation - Homo sapiens (human); hsa05034 Alcoholism - Homo sapiens (human); hsa04971 Gastric acid secretion - Homo sapiens (human); hsa04914 Progesterone-mediated oocyte maturation - Homo sapiens (human); hsa04915 Estrogen signaling pathway - Homo sapiens (human); hsa05032 Morphine addiction - Homo sapiens (human); hsa04725 Cholinergic synapse - Homo sapiens (human); hsa04921 Oxytocin signaling pathway - Homo sapiens (human); hsa05142 Chagas disease (American trypanosomiasis) - Homo sapiens (human); hsa04728 Dopaminergic synapse - Homo sapiens (human); hsa04371 Apelin signaling pathway - Homo sapiens (human); hsa04916 Melanogenesis - Homo sapiens (human); hsa04923 Regulation of lipolysis in adipocytes - Homo sapiens (human); hsa04024 cAMP signaling pathway - Homo sapiens (human); hsa04670 Leukocyte transendothelial migration - Homo sapiens (human); hsa05030 Cocaine addiction - Homo sapiens (human); hsa04726 Serotonergic synapse - Homo sapiens (human); hsa04062 Chemokine signaling pathway - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human); hsa04540 Gap junction - Homo sapiens (human); hsa04727 GABAergic synapse - Homo sapiens (human); hsa04730 Long-term depression - Homo sapiens (human); hsa05133 Pertussis - Homo sapiens (human); hsa04360 Axon guidance - Homo sapiens (human); hsa04926 Relaxin signaling pathway - Homo sapiens (human); hsa04928 Parathyroid hormone synthesis, secretion and action - Homo sapiens (human); hsa04713 Circadian entrainment - Homo sapiens (human); ","IPR027417; IPR011025; ","\"P-loop containing nucleoside triphosphate hydrolase; G protein alpha subunit, helical insertion; \"\r"]
["P08758","Annexin A5 OS=Homo sapiens OX=9606 GN=ANXA5","ANXA5",35.936,273.54,60.6,21,70,21,1.185,1.192,1.147,0.802,0.825,0.833,0.698,2.32e-05,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0044707 single-multicellular organism process; GO:0010941 regulation of cell death; GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0043069 negative regulation of programmed cell death; GO:0043067 regulation of programmed cell death; GO:0051241 negative regulation of multicellular organismal process; GO:0002576 platelet degranulation; GO:0044699 single-organism process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:0007599 hemostasis; GO:0051234 establishment of localization; GO:0009611 response to wounding; GO:0007165 signal transduction; GO:0007154 cell communication; GO:1902578 single-organism localization; GO:0043066 negative regulation of apoptotic process; GO:0009987 cellular process; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0051716 cellular response to stimulus; GO:0050878 regulation of body fluid levels; GO:0006950 response to stress; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0010033 response to organic substance; GO:0023052 signaling; GO:0043086 negative regulation of catalytic activity; GO:0032501 multicellular organismal process; GO:0050818 regulation of coagulation; GO:0006810 transport; GO:0045055 regulated exocytosis; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0042060 wound healing; GO:0050790 regulation of catalytic activity; GO:0032940 secretion by cell; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0050817 coagulation; GO:0051179 localization; GO:0060548 negative regulation of cell death; GO:0050819 negative regulation of coagulation; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; GO:0006887 exocytosis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005615 extracellular space; GO:0009897 external side of plasma membrane; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0098552 side of membrane; GO:0070161 anchoring junction; GO:0072563 endothelial microparticle; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0072562 blood microparticle; GO:0044459 plasma membrane part; GO:0009986 cell surface; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005544 calcium-dependent phospholipid binding; GO:0055102 lipase inhibitor activity; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0005543 phospholipid binding; GO:0043167 ion binding; GO:0008289 lipid binding; GO:0004859 phospholipase inhibitor activity; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0043168 anion binding; GO:0005509 calcium ion binding; GO:0098772 molecular function regulator; GO:0004857 enzyme inhibitor activity; ","K16646"]
["P08865","40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA","RPSA",32.854,156.34,44.4,11,24,11,0.91,0.932,0.936,1.073,1.064,1.072,1.155,9.74e-05,"cytoplasm\r","GO:0050658 RNA transport; GO:0044409 entry into host; GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0051029 rRNA transport; GO:0006518 peptide metabolic process; GO:0022618 ribonucleoprotein complex assembly; GO:0051169 nuclear transport; GO:0000460 maturation of 5.8S rRNA; GO:0071428 rRNA-containing ribonucleoprotein complex export from nucleus; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0043628 ncRNA 3'-end processing; GO:0022610 biological adhesion; GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0070972 protein localization to endoplasmic reticulum; GO:0015931 nucleobase-containing compound transport; GO:0065003 macromolecular complex assembly; GO:0006364 rRNA processing; GO:0007155 cell adhesion; GO:0019538 protein metabolic process; GO:0033365 protein localization to organelle; GO:0043170 macromolecule metabolic process; GO:0008104 protein localization; GO:0044419 interspecies interaction between organisms; GO:0044765 single-organism transport; GO:0046718 viral entry into host cell; GO:0006396 RNA processing; GO:0018130 heterocycle biosynthetic process; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0072657 protein localization to membrane; GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); GO:0042254 ribosome biogenesis; GO:0032774 RNA biosynthetic process; GO:0045047 protein targeting to ER; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0006611 protein export from nucleus; GO:0051704 multi-organism process; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006913 nucleocytoplasmic transport; GO:0090305 nucleic acid phosphodiester bond hydrolysis; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0030490 maturation of SSU-rRNA; GO:0046907 intracellular transport; GO:0051806 entry into cell of other organism involved in symbiotic interaction; GO:0044267 cellular protein metabolic process; GO:0048519 negative regulation of biological process; GO:0051236 establishment of RNA localization; GO:0044270 cellular nitrogen compound catabolic process; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0044248 cellular catabolic process; GO:1902580 single-organism cellular localization; GO:0034655 nucleobase-containing compound catabolic process; GO:0034613 cellular protein localization; GO:0090150 establishment of protein localization to membrane; GO:0031125 rRNA 3'-end processing; GO:0006403 RNA localization; GO:0006405 RNA export from nucleus; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0000028 ribosomal small subunit assembly; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0042255 ribosome assembly; GO:0045184 establishment of protein localization; GO:0006996 organelle organization; GO:0051179 localization; GO:1901564 organonitrogen compound metabolic process; GO:0072594 establishment of protein localization to organelle; GO:0000461 endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); GO:0044699 single-organism process; GO:0051168 nuclear export; GO:0009058 biosynthetic process; GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); GO:0044764 multi-organism cellular process; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0051649 establishment of localization in cell; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0071826 ribonucleoprotein complex subunit organization; GO:0050657 nucleic acid transport; GO:0022607 cellular component assembly; GO:0006413 translational initiation; GO:1901361 organic cyclic compound catabolic process; GO:0033036 macromolecule localization; GO:0006412 translation; GO:0034470 ncRNA processing; GO:0016072 rRNA metabolic process; GO:0010468 regulation of gene expression; GO:0043043 peptide biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:1902582 single-organism intracellular transport; GO:0071166 ribonucleoprotein complex localization; GO:0016070 RNA metabolic process; GO:0006401 RNA catabolic process; GO:0030260 entry into host cell; GO:0006407 rRNA export from nucleus; GO:0000469 cleavage involved in rRNA processing; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0051828 entry into other organism involved in symbiotic interaction; GO:0019222 regulation of metabolic process; GO:0019083 viral transcription; GO:0031123 RNA 3'-end processing; GO:0016043 cellular component organization; GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0006613 cotranslational protein targeting to membrane; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0070925 organelle assembly; GO:0016032 viral process; GO:0019080 viral gene expression; GO:0006886 intracellular protein transport; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0034622 cellular macromolecular complex assembly; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0042274 ribosomal small subunit biogenesis; GO:0006807 nitrogen compound metabolic process; GO:0051701 interaction with host; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0043933 macromolecular complex subunit organization; GO:0090501 RNA phosphodiester bond hydrolysis; GO:0070727 cellular macromolecule localization; GO:0071426 ribonucleoprotein complex export from nucleus; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic; GO:0009056 catabolic process; GO:0034660 ncRNA metabolic process; GO:0071705 nitrogen compound transport; GO:0065007 biological regulation; GO:0046700 heterocycle catabolic process; GO:0071840 cellular component organization or biogenesis; GO:0000478 endonucleolytic cleavage involved in rRNA processing; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0015935 small ribosomal subunit; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0030684 preribosome; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0044391 ribosomal subunit; GO:1903561 extracellular vesicle; GO:0044445 cytosolic part; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0022626 cytosolic ribosome; GO:0005840 ribosome; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0030686 90S preribosome; GO:0005634 nucleus; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0022627 cytosolic small ribosomal subunit; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0003723 RNA binding; GO:0044877 macromolecular complex binding; GO:0005055 laminin receptor activity; GO:0005515 protein binding; GO:0003735 structural constituent of ribosome; GO:0001618 virus receptor activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0043022 ribosome binding; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005198 structural molecule activity; GO:0043021 ribonucleoprotein complex binding; ","K02998","RP-SAe; small subunit ribosomal protein SAe","hsa03010 Ribosome - Homo sapiens (human); ","IPR023591; IPR032281; ","\"Ribosomal protein S2, flavodoxin-like domain; 40S ribosomal protein SA, C-terminal domain; \"\r"]
["P08962","CD63 antigen OS=Homo sapiens OX=9606 GN=CD63","CD63",25.636,3.9913,7.6,2,3,2,1.208,1.235,1.101,0.799,0.819,0.871,0.702,0.00126,"plasma membrane\r","GO:0060627 regulation of vesicle-mediated transport; GO:0021700 developmental maturation; GO:0045321 leukocyte activation; GO:0051674 localization of cell; GO:0002092 positive regulation of receptor internalization; GO:0023051 regulation of signaling; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0009605 response to external stimulus; GO:0022610 biological adhesion; GO:0010646 regulation of cell communication; GO:0009893 positive regulation of metabolic process; GO:0032879 regulation of localization; GO:0007160 cell-matrix adhesion; GO:0007155 cell adhesion; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0043476 pigment accumulation; GO:0048259 regulation of receptor-mediated endocytosis; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0043269 regulation of ion transport; GO:0048757 pigment granule maturation; GO:0048522 positive regulation of cellular process; GO:0090287 regulation of cellular response to growth factor stimulus; GO:0048870 cell motility; GO:0031323 regulation of cellular metabolic process; GO:1900746 regulation of vascular endothelial growth factor signaling pathway; GO:0002444 myeloid leukocyte mediated immunity; GO:2001046 positive regulation of integrin-mediated signaling pathway; GO:0051050 positive regulation of transport; GO:0016197 endosomal transport; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0032940 secretion by cell; GO:0048583 regulation of response to stimulus; GO:0019222 regulation of metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0043299 leukocyte degranulation; GO:0040011 locomotion; GO:0048260 positive regulation of receptor-mediated endocytosis; GO:0050794 regulation of cellular process; GO:0016477 cell migration; GO:2000680 regulation of rubidium ion transport; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0045807 positive regulation of endocytosis; GO:0060255 regulation of macromolecule metabolic process; GO:0043485 endosome to pigment granule transport; GO:0002576 platelet degranulation; GO:0048066 developmental pigmentation; GO:0050896 response to stimulus; GO:0050931 pigment cell differentiation; GO:2001044 regulation of integrin-mediated signaling pathway; GO:0030154 cell differentiation; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0023056 positive regulation of signaling; GO:0010959 regulation of metal ion transport; GO:0010647 positive regulation of cell communication; GO:0036230 granulocyte activation; GO:0034613 cellular protein localization; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:0002090 regulation of receptor internalization; GO:0030100 regulation of endocytosis; GO:0051049 regulation of transport; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0071702 organic substance transport; GO:0043312 neutrophil degranulation; GO:0002263 cell activation involved in immune response; GO:0048518 positive regulation of biological process; GO:0035646 endosome to melanosome transport; GO:0051641 cellular localization; GO:0002366 leukocyte activation involved in immune response; GO:0045184 establishment of protein localization; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0070727 cellular macromolecule localization; GO:1902547 regulation of cellular response to vascular endothelial growth factor stimulus; GO:0031589 cell-substrate adhesion; GO:0044767 single-organism developmental process; GO:0031325 positive regulation of cellular metabolic process; GO:0001775 cell activation; GO:0043473 pigmentation; GO:0006928 movement of cell or subcellular component; GO:0009967 positive regulation of signal transduction; GO:0051128 regulation of cellular component organization; GO:0048584 positive regulation of response to stimulus; GO:0006955 immune response; GO:0051179 localization; GO:0033059 cellular pigmentation; GO:0043482 cellular pigment accumulation; GO:0065007 biological regulation; GO:0006887 exocytosis; ","GO:0016020 membrane; GO:0042827 platelet dense granule; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0031088 platelet dense granule membrane; GO:0044433 cytoplasmic vesicle part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0005765 lysosomal membrane; GO:0070062 extracellular exosome; GO:0031902 late endosome membrane; GO:0005622 intracellular; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:0043227 membrane-bounded organelle; GO:0005771 multivesicular body; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0010008 endosome membrane; GO:0031226 intrinsic component of plasma membrane; GO:0005770 late endosome; GO:0035577 azurophil granule membrane; GO:0044440 endosomal part; GO:0012506 vesicle membrane; GO:0005576 extracellular region; GO:0031904 endosome lumen; GO:0005886 plasma membrane; GO:0042582 azurophil granule; GO:0043231 intracellular membrane-bounded organelle; GO:0030667 secretory granule membrane; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043230 extracellular organelle; GO:0005615 extracellular space; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0048770 pigment granule; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0030141 secretory granule; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0042470 melanosome; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0016021 integral component of membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0032585 multivesicular body membrane; GO:0097487 multivesicular body, internal vesicle; GO:0005774 vacuolar membrane; GO:0009986 cell surface; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ","K06497","CD63; CD63 antigen","hsa04142 Lysosome - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); ","IPR008952; ","\"Tetraspanin, EC2 domain; \"\r"]
["P09012","U1 small nuclear ribonucleoprotein A OS=Homo sapiens OX=9606 GN=SNRPA","SNRPA",31.279,13.817,20.9,6,9,4,1.01,0.983,0.955,0.988,1.061,1.028,1.044,0.179,"nucleus\r","GO:0050794 regulation of cellular process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0008152 metabolic process; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0031440 regulation of mRNA 3'-end processing; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0006396 RNA processing; GO:0010468 regulation of gene expression; GO:0080090 regulation of primary metabolic process; GO:1900363 regulation of mRNA polyadenylation; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0050684 regulation of mRNA processing; GO:0031323 regulation of cellular metabolic process; GO:0044238 primary metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:1903311 regulation of mRNA metabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0010467 gene expression; GO:0016071 mRNA metabolic process; GO:0065007 biological regulation; ","GO:0005685 U1 snRNP; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005681 spliceosomal complex; GO:0005623 cell; GO:0044422 organelle part; GO:0097525 spliceosomal snRNP complex; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0030532 small nuclear ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0070990 snRNP binding; GO:0003723 RNA binding; GO:0035613 RNA stem-loop binding; GO:1901265 nucleoside phosphate binding; GO:0044877 macromolecular complex binding; GO:0005515 protein binding; GO:0030619 U1 snRNA binding; GO:0000166 nucleotide binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0042802 identical protein binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0043021 ribonucleoprotein complex binding; GO:0017069 snRNA binding; GO:1990446 U1 snRNP binding; GO:0036094 small molecule binding; GO:0035614 snRNA stem-loop binding; ","K11091","SNRPA; U1 small nuclear ribonucleoprotein A","hsa03040 Spliceosome - Homo sapiens (human); ","IPR000504; IPR012677; ","RNA recognition motif domain; Nucleotide-binding alpha-beta plait domain; \r"]
["P09104","Gamma-enolase OS=Homo sapiens OX=9606 GN=ENO2","ENO2",47.268,26.276,15.9,5,11,3,1.032,0.997,1.004,1.026,0.994,0.958,0.982,0.454,"cytoplasm\r","GO:0046365 monosaccharide catabolic process; GO:0006757 ATP generation from ADP; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0006165 nucleoside diphosphate phosphorylation; GO:0046031 ADP metabolic process; GO:0019362 pyridine nucleotide metabolic process; GO:0019319 hexose biosynthetic process; GO:0006096 glycolytic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0009185 ribonucleoside diphosphate metabolic process; GO:0046939 nucleotide phosphorylation; GO:0009135 purine nucleoside diphosphate metabolic process; GO:0044237 cellular metabolic process; GO:0072524 pyridine-containing compound metabolic process; GO:0061615 glycolytic process through fructose-6-phosphate; GO:0006796 phosphate-containing compound metabolic process; GO:0006006 glucose metabolic process; GO:0008152 metabolic process; GO:0006094 gluconeogenesis; GO:0006091 generation of precursor metabolites and energy; GO:0006753 nucleoside phosphate metabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0009179 purine ribonucleoside diphosphate metabolic process; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0061620 glycolytic process through glucose-6-phosphate; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0072521 purine-containing compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0006732 coenzyme metabolic process; GO:0005975 carbohydrate metabolic process; GO:0061718 glucose catabolic process to pyruvate; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0016052 carbohydrate catabolic process; GO:0051186 cofactor metabolic process; GO:1901575 organic substance catabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0019674 NAD metabolic process; GO:0044710 single-organism metabolic process; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0006082 organic acid metabolic process; GO:0043436 oxoacid metabolic process; GO:0016310 phosphorylation; GO:0016051 carbohydrate biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0046496 nicotinamide nucleotide metabolic process; GO:0009259 ribonucleotide metabolic process; GO:0006734 NADH metabolic process; GO:0046364 monosaccharide biosynthetic process; GO:0006735 NADH regeneration; GO:0071704 organic substance metabolic process; GO:0061621 canonical glycolysis; GO:0006090 pyruvate metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0005996 monosaccharide metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0009987 cellular process; GO:0009119 ribonucleoside metabolic process; GO:0009132 nucleoside diphosphate metabolic process; GO:0046034 ATP metabolic process; GO:0044724 single-organism carbohydrate catabolic process; GO:0044711 single-organism biosynthetic process; GO:0044712 single-organism catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044282 small molecule catabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0006163 purine nucleotide metabolic process; GO:0046128 purine ribonucleoside metabolic process; GO:0006007 glucose catabolic process; GO:0006793 phosphorus metabolic process; GO:0044283 small molecule biosynthetic process; GO:0019752 carboxylic acid metabolic process; GO:0019637 organophosphate metabolic process; GO:0019320 hexose catabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0009056 catabolic process; GO:0019318 hexose metabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0043025 neuronal cell body; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:1902494 catalytic complex; GO:0036477 somatodendritic compartment; GO:0001917 photoreceptor inner segment; GO:0043209 myelin sheath; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043204 perikaryon; GO:0044445 cytosolic part; GO:0044297 cell body; GO:0043227 membrane-bounded organelle; GO:0000015 phosphopyruvate hydratase complex; GO:0097458 neuron part; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0000287 magnesium ion binding; GO:0004634 phosphopyruvate hydratase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0016829 lyase activity; GO:0005515 protein binding; GO:0016836 hydro-lyase activity; GO:0016835 carbon-oxygen lyase activity; ","K01689","ENO; enolase [EC:4.2.1.11]","hsa03018 RNA degradation - Homo sapiens (human); hsa04066 HIF-1 signaling pathway - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human); hsa01230 Biosynthesis of amino acids - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); ","IPR029065; IPR020810; IPR029017; IPR020811; ","\"Enolase C-terminal domain-like; Enolase, C-terminal TIM barrel domain; Enolase N-terminal domain-like; Enolase, N-terminal; \"\r"]
["P09110","3-ketoacyl-CoA thiolase, peroxisomal OS=Homo sapiens OX=9606 GN=ACAA1","ACAA1",44.292,104.96,28.8,7,11,7,1.083,1.078,1.062,0.964,0.916,0.883,0.857,0.00408,"mitochondria\r","GO:0045321 leukocyte activation; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0030258 lipid modification; GO:0032787 monocarboxylic acid metabolic process; GO:0008206 bile acid metabolic process; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0006629 lipid metabolic process; GO:0019395 fatty acid oxidation; GO:0002443 leukocyte mediated immunity; GO:0055114 oxidation-reduction process; GO:0002446 neutrophil mediated immunity; GO:0044281 small molecule metabolic process; GO:0008202 steroid metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0072329 monocarboxylic acid catabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0006810 transport; GO:0046395 carboxylic acid catabolic process; GO:1901575 organic substance catabolic process; GO:0032940 secretion by cell; GO:0044710 single-organism metabolic process; GO:0043299 leukocyte degranulation; GO:0006082 organic acid metabolic process; GO:0009062 fatty acid catabolic process; GO:0043436 oxoacid metabolic process; GO:0033559 unsaturated fatty acid metabolic process; GO:0034440 lipid oxidation; GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase; GO:0002283 neutrophil activation involved in immune response; GO:1901615 organic hydroxy compound metabolic process; GO:0002252 immune effector process; GO:0036109 alpha-linolenic acid metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0044248 cellular catabolic process; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0016042 lipid catabolic process; GO:0044712 single-organism catabolic process; GO:0016192 vesicle-mediated transport; GO:0006635 fatty acid beta-oxidation; GO:0044282 small molecule catabolic process; GO:0002376 immune system process; GO:0006631 fatty acid metabolic process; GO:0044238 primary metabolic process; GO:0043312 neutrophil degranulation; GO:0002263 cell activation involved in immune response; GO:0002366 leukocyte activation involved in immune response; GO:0000038 very long-chain fatty acid metabolic process; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0001676 long-chain fatty acid metabolic process; GO:0016054 organic acid catabolic process; GO:0019752 carboxylic acid metabolic process; GO:0044242 cellular lipid catabolic process; GO:0001775 cell activation; GO:0006955 immune response; GO:0051179 localization; GO:0009056 catabolic process; GO:0006887 exocytosis; ","GO:0034774 secretory granule lumen; GO:0016020 membrane; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044438 microbody part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005782 peroxisomal matrix; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0042579 microbody; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0044439 peroxisomal part; GO:0005777 peroxisome; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031907 microbody lumen; GO:0060205 cytoplasmic vesicle lumen; GO:0035580 specific granule lumen; GO:0042581 specific granule; GO:0044444 cytoplasmic part; ","GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor; GO:0005515 protein binding; GO:0003997 acyl-CoA oxidase activity; GO:0016401 palmitoyl-CoA oxidase activity; GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups; GO:0016491 oxidoreductase activity; GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors; GO:0008410 CoA-transferase activity; GO:0016746 transferase activity, transferring acyl groups; GO:0003824 catalytic activity; GO:0005488 binding; GO:0003988 acetyl-CoA C-acyltransferase activity; GO:0008775 acetate CoA-transferase activity; GO:0016782 transferase activity, transferring sulfur-containing groups; GO:0016408 C-acyltransferase activity; GO:0016740 transferase activity; ","K07513","ACAA1; acetyl-CoA acyltransferase 1 [EC:2.3.1.16]","hsa00280 Valine, leucine and isoleucine degradation - Homo sapiens (human); hsa03320 PPAR signaling pathway - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa01212 Fatty acid metabolism - Homo sapiens (human); hsa00592 alpha-Linolenic acid metabolism - Homo sapiens (human); hsa04146 Peroxisome - Homo sapiens (human); hsa00071 Fatty acid degradation - Homo sapiens (human); hsa01040 Biosynthesis of unsaturated fatty acids - Homo sapiens (human); ","IPR016039; IPR020616; IPR020617; ","\"Thiolase-like; Thiolase, N-terminal; Thiolase, C-terminal; \"\r"]
["P09211","Glutathione S-transferase P OS=Homo sapiens OX=9606 GN=GSTP1","GSTP1",23.356,212.06,59.5,9,34,9,0.957,0.944,0.961,1.019,1.047,0.991,1.068,0.0173,"mitochondria\r","GO:0010941 regulation of cell death; GO:0032872 regulation of stress-activated MAPK cascade; GO:0032680 regulation of tumor necrosis factor production; GO:0071384 cellular response to corticosteroid stimulus; GO:0044255 cellular lipid metabolic process; GO:0031347 regulation of defense response; GO:0044237 cellular metabolic process; GO:0009607 response to biotic stimulus; GO:0048145 regulation of fibroblast proliferation; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0008152 metabolic process; GO:0070664 negative regulation of leukocyte proliferation; GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling; GO:0098869 cellular oxidant detoxification; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0080090 regulation of primary metabolic process; GO:0043508 negative regulation of JUN kinase activity; GO:0043651 linoleic acid metabolic process; GO:0044763 single-organism cellular process; GO:0032692 negative regulation of interleukin-1 production; GO:0043086 negative regulation of catalytic activity; GO:0051704 multi-organism process; GO:0071396 cellular response to lipid; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0006810 transport; GO:0010243 response to organonitrogen compound; GO:0042063 gliogenesis; GO:1902532 negative regulation of intracellular signal transduction; GO:0080135 regulation of cellular response to stress; GO:0071638 negative regulation of monocyte chemotactic protein-1 production; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0014912 negative regulation of smooth muscle cell migration; GO:0060548 negative regulation of cell death; GO:0043436 oxoacid metabolic process; GO:0033559 unsaturated fatty acid metabolic process; GO:0044707 single-multicellular organism process; GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway; GO:0043407 negative regulation of MAP kinase activity; GO:0050728 negative regulation of inflammatory response; GO:1901700 response to oxygen-containing compound; GO:0048519 negative regulation of biological process; GO:0035732 nitric oxide storage; GO:1990748 cellular detoxification; GO:0023057 negative regulation of signaling; GO:0009410 response to xenobiotic stimulus; GO:0010648 negative regulation of cell communication; GO:2000145 regulation of cell motility; GO:0009889 regulation of biosynthetic process; GO:0035726 common myeloid progenitor cell proliferation; GO:0048878 chemical homeostasis; GO:0044711 single-organism biosynthetic process; GO:0006950 response to stress; GO:0032720 negative regulation of tumor necrosis factor production; GO:0051270 regulation of cellular component movement; GO:0032496 response to lipopolysaccharide; GO:0002376 immune system process; GO:0008283 cell proliferation; GO:0032101 regulation of response to external stimulus; GO:0010033 response to organic substance; GO:0007584 response to nutrient; GO:1901576 organic substance biosynthetic process; GO:0002263 cell activation involved in immune response; GO:0045055 regulated exocytosis; GO:0009890 negative regulation of biosynthetic process; GO:0030336 negative regulation of cell migration; GO:0001676 long-chain fatty acid metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0071219 cellular response to molecule of bacterial origin; GO:0071637 regulation of monocyte chemotactic protein-1 production; GO:0006955 immune response; GO:0045936 negative regulation of phosphate metabolic process; GO:0032930 positive regulation of superoxide anion generation; GO:0031100 animal organ regeneration; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0051769 regulation of nitric-oxide synthase biosynthetic process; GO:0009058 biosynthetic process; GO:0071383 cellular response to steroid hormone stimulus; GO:0031400 negative regulation of protein modification process; GO:0040013 negative regulation of locomotion; GO:1901653 cellular response to peptide; GO:0009893 positive regulation of metabolic process; GO:0032642 regulation of chemokine production; GO:0032873 negative regulation of stress-activated MAPK cascade; GO:0070663 regulation of leukocyte proliferation; GO:0033273 response to vitamin; GO:0006629 lipid metabolic process; GO:0043200 response to amino acid; GO:0002237 response to molecule of bacterial origin; GO:0009636 response to toxic substance; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0071417 cellular response to organonitrogen compound; GO:0032868 response to insulin; GO:0032940 secretion by cell; GO:0032682 negative regulation of chemokine production; GO:2001236 regulation of extrinsic apoptotic signaling pathway; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:2000377 regulation of reactive oxygen species metabolic process; GO:0098754 detoxification; GO:0043549 regulation of kinase activity; GO:0043069 negative regulation of programmed cell death; GO:0032691 negative regulation of interleukin-1 beta production; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0001959 regulation of cytokine-mediated signaling pathway; GO:0002673 regulation of acute inflammatory response; GO:1901566 organonitrogen compound biosynthetic process; GO:0051707 response to other organism; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0033993 response to lipid; GO:0030154 cell differentiation; GO:0006805 xenobiotic metabolic process; GO:0006575 cellular modified amino acid metabolic process; GO:0043066 negative regulation of apoptotic process; GO:0043408 regulation of MAPK cascade; GO:0031960 response to corticosteroid; GO:0034641 cellular nitrogen compound metabolic process; GO:0031348 negative regulation of defense response; GO:0001932 regulation of protein phosphorylation; GO:0050920 regulation of chemotaxis; GO:0044249 cellular biosynthetic process; GO:1901687 glutathione derivative biosynthetic process; GO:0002366 leukocyte activation involved in immune response; GO:0033483 gas homeostasis; GO:0048662 negative regulation of smooth muscle cell proliferation; GO:0010001 glial cell differentiation; GO:0042119 neutrophil activation; GO:1901701 cellular response to oxygen-containing compound; GO:0071495 cellular response to endogenous stimulus; GO:0010563 negative regulation of phosphorus metabolic process; GO:0050727 regulation of inflammatory response; GO:0019752 carboxylic acid metabolic process; GO:0001817 regulation of cytokine production; GO:0051248 negative regulation of protein metabolic process; GO:0031099 regeneration; GO:0042981 regulation of apoptotic process; GO:0014910 regulation of smooth muscle cell migration; GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0006518 peptide metabolic process; GO:0032651 regulation of interleukin-1 beta production; GO:0033484 nitric oxide homeostasis; GO:0043506 regulation of JUN kinase activity; GO:0044272 sulfur compound biosynthetic process; GO:0008285 negative regulation of cell proliferation; GO:0009605 response to external stimulus; GO:1901685 glutathione derivative metabolic process; GO:0048709 oligodendrocyte differentiation; GO:0032879 regulation of localization; GO:0032102 negative regulation of response to external stimulus; GO:0048545 response to steroid hormone; GO:0070303 negative regulation of stress-activated protein kinase signaling cascade; GO:0009719 response to endogenous stimulus; GO:0032787 monocarboxylic acid metabolic process; GO:0090322 regulation of superoxide metabolic process; GO:0070848 response to growth factor; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0009743 response to carbohydrate; GO:1901652 response to peptide; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0032928 regulation of superoxide anion generation; GO:0007399 nervous system development; GO:0006790 sulfur compound metabolic process; GO:0071460 cellular response to cell-matrix adhesion; GO:0014070 response to organic cyclic compound; GO:0002443 leukocyte mediated immunity; GO:0051174 regulation of phosphorus metabolic process; GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process; GO:0044281 small molecule metabolic process; GO:0000302 response to reactive oxygen species; GO:0046329 negative regulation of JNK cascade; GO:0031323 regulation of cellular metabolic process; GO:2000146 negative regulation of cell motility; GO:0032501 multicellular organismal process; GO:0048513 animal organ development; GO:0007417 central nervous system development; GO:0032269 negative regulation of cellular protein metabolic process; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0071364 cellular response to epidermal growth factor stimulus; GO:0060759 regulation of response to cytokine stimulus; GO:0034284 response to monosaccharide; GO:0032869 cellular response to insulin stimulus; GO:1904705 regulation of vascular smooth muscle cell proliferation; GO:0050794 regulation of cellular process; GO:0002283 neutrophil activation involved in immune response; GO:0042127 regulation of cell proliferation; GO:0071672 negative regulation of smooth muscle cell chemotaxis; GO:0031399 regulation of protein modification process; GO:0043067 regulation of programmed cell death; GO:0032355 response to estradiol; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:0002674 negative regulation of acute inflammatory response; GO:0051239 regulation of multicellular organismal process; GO:0033591 response to L-ascorbic acid; GO:0070372 regulation of ERK1 and ERK2 cascade; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0051338 regulation of transferase activity; GO:0070373 negative regulation of ERK1 and ERK2 cascade; GO:0001933 negative regulation of protein phosphorylation; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:0009617 response to bacterium; GO:1902531 regulation of intracellular signal transduction; GO:0071385 cellular response to glucocorticoid stimulus; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:2001237 negative regulation of extrinsic apoptotic signaling pathway; GO:0071407 cellular response to organic cyclic compound; GO:0071496 cellular response to external stimulus; GO:0030334 regulation of cell migration; GO:0097305 response to alcohol; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0031668 cellular response to extracellular stimulus; GO:0060761 negative regulation of response to cytokine stimulus; GO:0043409 negative regulation of MAPK cascade; GO:0001775 cell activation; GO:0051179 localization; GO:0006887 exocytosis; GO:1901564 organonitrogen compound metabolic process; GO:1903555 regulation of tumor necrosis factor superfamily cytokine production; GO:0001101 response to acid chemical; GO:0050922 negative regulation of chemotaxis; GO:0022008 neurogenesis; GO:0051241 negative regulation of multicellular organismal process; GO:0071363 cellular response to growth factor stimulus; GO:0014003 oligodendrocyte development; GO:0001818 negative regulation of cytokine production; GO:0051234 establishment of localization; GO:2001233 regulation of apoptotic signaling pathway; GO:0010646 regulation of cell communication; GO:0070302 regulation of stress-activated protein kinase signaling cascade; GO:0007154 cell communication; GO:0071901 negative regulation of protein serine/threonine kinase activity; GO:0048147 negative regulation of fibroblast proliferation; GO:0033673 negative regulation of kinase activity; GO:0006979 response to oxidative stress; GO:0006749 glutathione metabolic process; GO:0046328 regulation of JNK cascade; GO:0070887 cellular response to chemical stimulus; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:0002446 neutrophil mediated immunity; GO:0048522 positive regulation of cellular process; GO:0043603 cellular amide metabolic process; GO:0051348 negative regulation of transferase activity; GO:0051384 response to glucocorticoid; GO:1904706 negative regulation of vascular smooth muscle cell proliferation; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0043434 response to peptide hormone; GO:1901699 cellular response to nitrogen compound; GO:0032870 cellular response to hormone stimulus; GO:0021782 glial cell development; GO:0019222 regulation of metabolic process; GO:0006469 negative regulation of protein kinase activity; GO:0043299 leukocyte degranulation; GO:0019220 regulation of phosphate metabolic process; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:0051271 negative regulation of cellular component movement; GO:0045859 regulation of protein kinase activity; GO:0071466 cellular response to xenobiotic stimulus; GO:0071222 cellular response to lipopolysaccharide; GO:0002252 immune effector process; GO:0043405 regulation of MAP kinase activity; GO:0048660 regulation of smooth muscle cell proliferation; GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway; GO:0045471 response to ethanol; GO:0031324 negative regulation of cellular metabolic process; GO:0043207 response to external biotic stimulus; GO:0071671 regulation of smooth muscle cell chemotaxis; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0001960 negative regulation of cytokine-mediated signaling pathway; GO:0009991 response to extracellular stimulus; GO:0071216 cellular response to biotic stimulus; GO:0042326 negative regulation of phosphorylation; GO:1903556 negative regulation of tumor necrosis factor superfamily cytokine production; GO:0071375 cellular response to peptide hormone stimulus; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0032652 regulation of interleukin-1 production; GO:0070849 response to epidermal growth factor; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0006631 fatty acid metabolic process; GO:0048585 negative regulation of response to stimulus; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling; GO:2000379 positive regulation of reactive oxygen species metabolic process; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0031667 response to nutrient levels; GO:0009725 response to hormone; GO:0040012 regulation of locomotion; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0097057 TRAF2-GSTP1 complex; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0101002 ficolin-1-rich granule; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0004602 glutathione peroxidase activity; GO:0043167 ion binding; GO:0019901 protein kinase binding; GO:0016209 antioxidant activity; GO:0005515 protein binding; GO:0033218 amide binding; GO:0043295 glutathione binding; GO:0019207 kinase regulator activity; GO:0008144 drug binding; GO:1900750 oligopeptide binding; GO:0098772 molecular function regulator; GO:0019900 kinase binding; GO:1901681 sulfur compound binding; GO:0016491 oxidoreductase activity; GO:0004364 glutathione transferase activity; GO:0072341 modified amino acid binding; GO:0030234 enzyme regulator activity; GO:0035730 S-nitrosoglutathione binding; GO:0008432 JUN kinase binding; GO:0070026 nitric oxide binding; GO:0042277 peptide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups; GO:0043168 anion binding; GO:0004601 peroxidase activity; GO:0016740 transferase activity; GO:0019899 enzyme binding; GO:0035731 dinitrosyl-iron complex binding; GO:0016684 oxidoreductase activity, acting on peroxide as acceptor; ","K00799","GST; glutathione S-transferase [EC:2.5.1.18]","hsa01524 Platinum drug resistance - Homo sapiens (human); hsa00480 Glutathione metabolism - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa05204 Chemical carcinogenesis - Homo sapiens (human); hsa00980 Metabolism of xenobiotics by cytochrome P450 - Homo sapiens (human); hsa05225 Hepatocellular carcinoma - Homo sapiens (human); hsa00983 Drug metabolism - other enzymes - Homo sapiens (human); hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human); hsa00982 Drug metabolism - cytochrome P450 - Homo sapiens (human); hsa05215 Prostate cancer - Homo sapiens (human); ","IPR004046; IPR010987; IPR004045; IPR012336; ","\"Glutathione S-transferase, C-terminal; Glutathione S-transferase, C-terminal-like; Glutathione S-transferase, N-terminal; Thioredoxin-like fold; \"\r"]
["P09234","U1 small nuclear ribonucleoprotein C OS=Homo sapiens OX=9606 GN=SNRPC","SNRPC",17.394,5.9021,13.2,2,2,2,0.964,0.863,0.906,1.056,1.14,1.066,1.194,0.0115,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0016043 cellular component organization; GO:0006376 mRNA splice site selection; GO:0022613 ribonucleoprotein complex biogenesis; GO:0022618 ribonucleoprotein complex assembly; GO:0006725 cellular aromatic compound metabolic process; GO:0045292 mRNA cis splicing, via spliceosome; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0008152 metabolic process; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0071826 ribonucleoprotein complex subunit organization; GO:0000395 mRNA 5'-splice site recognition; GO:0046483 heterocycle metabolic process; GO:0022607 cellular component assembly; GO:0006139 nucleobase-containing compound metabolic process; GO:0065003 macromolecular complex assembly; GO:0000375 RNA splicing, via transesterification reactions; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0009987 cellular process; GO:0008380 RNA splicing; GO:0006396 RNA processing; GO:0034622 cellular macromolecular complex assembly; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0044238 primary metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:0090304 nucleic acid metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0000245 spliceosomal complex assembly; GO:0016071 mRNA metabolic process; GO:0000387 spliceosomal snRNP assembly; GO:0071840 cellular component organization or biogenesis; ","GO:0005685 U1 snRNP; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0005684 U2-type spliceosomal complex; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005681 spliceosomal complex; GO:0016604 nuclear body; GO:0005623 cell; GO:0015030 Cajal body; GO:0044422 organelle part; GO:0097525 spliceosomal snRNP complex; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0071010 prespliceosome; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0030532 small nuclear ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0000243 commitment complex; GO:0044428 nuclear part; ","GO:0070990 snRNP binding; GO:0003723 RNA binding; GO:0044877 macromolecular complex binding; GO:0046983 protein dimerization activity; GO:0043167 ion binding; GO:0005515 protein binding; GO:0008270 zinc ion binding; GO:0003727 single-stranded RNA binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0042802 identical protein binding; GO:0046914 transition metal ion binding; GO:0005488 binding; GO:0042803 protein homodimerization activity; GO:0003676 nucleic acid binding; GO:0036002 pre-mRNA binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0030627 pre-mRNA 5'-splice site binding; GO:0043021 ribonucleoprotein complex binding; GO:1990446 U1 snRNP binding; ","K11095","SNRPC; U1 small nuclear ribonucleoprotein C","hsa03040 Spliceosome - Homo sapiens (human); ","IPR013085; IPR003604; IPR000690; ","\"Zinc finger, U1-C type; Zinc finger, U1-type; Zinc finger, C2H2-type matrin; \"\r"]
["P09382","Galectin-1 OS=Homo sapiens OX=9606 GN=LGALS1","LGALS1",14.716,62.389,64.4,8,37,8,1.169,1.104,1.155,0.847,0.868,0.841,0.746,1.21E-4,"extracellular\r","GO:0044700 single organism signaling; GO:0002694 regulation of leukocyte activation; GO:0010941 regulation of cell death; GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0042593 glucose homeostasis; GO:0045445 myoblast differentiation; GO:0009749 response to glucose; GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling; GO:0071333 cellular response to glucose stimulus; GO:0001678 cellular glucose homeostasis; GO:0071322 cellular response to carbohydrate stimulus; GO:0009743 response to carbohydrate; GO:0007399 nervous system development; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0002520 immune system development; GO:0002335 mature B cell differentiation; GO:0030183 B cell differentiation; GO:0032501 multicellular organismal process; GO:0034120 positive regulation of erythrocyte aggregation; GO:0050768 negative regulation of neurogenesis; GO:0048513 animal organ development; GO:0048583 regulation of response to stimulus; GO:0034284 response to monosaccharide; GO:0045665 negative regulation of neuron differentiation; GO:0002682 regulation of immune system process; GO:0010721 negative regulation of cell development; GO:0010975 regulation of neuron projection development; GO:0034118 regulation of erythrocyte aggregation; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0007162 negative regulation of cell adhesion; GO:0043067 regulation of programmed cell death; GO:1901700 response to oxygen-containing compound; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0051239 regulation of multicellular organismal process; GO:0030098 lymphocyte differentiation; GO:0042493 response to drug; GO:0050867 positive regulation of cell activation; GO:0046598 positive regulation of viral entry into host cell; GO:0031345 negative regulation of cell projection organization; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:0033500 carbohydrate homeostasis; GO:0061061 muscle structure development; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:0048878 chemical homeostasis; GO:1902531 regulation of intracellular signal transduction; GO:0002285 lymphocyte activation involved in immune response; GO:0006950 response to stress; GO:0045785 positive regulation of cell adhesion; GO:0048731 system development; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0043900 regulation of multi-organism process; GO:0010977 negative regulation of neuron projection development; GO:0071407 cellular response to organic cyclic compound; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0034110 regulation of homotypic cell-cell adhesion; GO:1903039 positive regulation of leukocyte cell-cell adhesion; GO:0002263 cell activation involved in immune response; GO:0030155 regulation of cell adhesion; GO:0002696 positive regulation of leukocyte activation; GO:0048678 response to axon injury; GO:0071326 cellular response to monosaccharide stimulus; GO:0050870 positive regulation of T cell activation; GO:0001775 cell activation; GO:0012501 programmed cell death; GO:0010810 regulation of cell-substrate adhesion; GO:0048584 positive regulation of response to stimulus; GO:0006955 immune response; GO:0050793 regulation of developmental process; GO:0050863 regulation of T cell activation; GO:0051093 negative regulation of developmental process; GO:0071331 cellular response to hexose stimulus; GO:0009746 response to hexose; GO:0023051 regulation of signaling; GO:0048869 cellular developmental process; GO:0051129 negative regulation of cellular component organization; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0051241 negative regulation of multicellular organismal process; GO:0022008 neurogenesis; GO:0031294 lymphocyte costimulation; GO:0051249 regulation of lymphocyte activation; GO:0009611 response to wounding; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0002313 mature B cell differentiation involved in immune response; GO:0006915 apoptotic process; GO:0046596 regulation of viral entry into host cell; GO:0045596 negative regulation of cell differentiation; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:1903902 positive regulation of viral life cycle; GO:0043902 positive regulation of multi-organism process; GO:0002521 leukocyte differentiation; GO:0048522 positive regulation of cellular process; GO:0019725 cellular homeostasis; GO:0051251 positive regulation of lymphocyte activation; GO:0023052 signaling; GO:0002312 B cell activation involved in immune response; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0050865 regulation of cell activation; GO:0045664 regulation of neuron differentiation; GO:0035900 response to isolation stress; GO:0010812 negative regulation of cell-substrate adhesion; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0002317 plasma cell differentiation; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0002252 immune effector process; GO:0071310 cellular response to organic substance; GO:0031344 regulation of cell projection organization; GO:0050896 response to stimulus; GO:0055082 cellular chemical homeostasis; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:0051961 negative regulation of nervous system development; GO:0023056 positive regulation of signaling; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:0042113 B cell activation; GO:0045595 regulation of cell differentiation; GO:0022409 positive regulation of cell-cell adhesion; GO:0031295 T cell costimulation; GO:0050792 regulation of viral process; GO:0046649 lymphocyte activation; GO:0048518 positive regulation of biological process; GO:0048534 hematopoietic or lymphoid organ development; GO:0030097 hemopoiesis; GO:0022407 regulation of cell-cell adhesion; GO:0002366 leukocyte activation involved in immune response; GO:0034112 positive regulation of homotypic cell-cell adhesion; GO:1901701 cellular response to oxygen-containing compound; GO:0048524 positive regulation of viral process; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0002684 positive regulation of immune system process; GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling; GO:0042692 muscle cell differentiation; GO:0009967 positive regulation of signal transduction; GO:0051128 regulation of cellular component organization; GO:1903900 regulation of viral life cycle; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; GO:0050767 regulation of neurogenesis; ","GO:0043229 intracellular organelle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0031012 extracellular matrix; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0005578 proteinaceous extracellular matrix; GO:0009986 cell surface; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0003723 RNA binding; GO:0030395 lactose binding; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:0004871 signal transducer activity; GO:0050840 extracellular matrix binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0097367 carbohydrate derivative binding; GO:0042802 identical protein binding; GO:0043236 laminin binding; GO:0070492 oligosaccharide binding; GO:0005488 binding; GO:0042803 protein homodimerization activity; GO:0003676 nucleic acid binding; GO:0030246 carbohydrate binding; GO:0048030 disaccharide binding; GO:0001948 glycoprotein binding; ","K06830",null,null,"IPR001079; IPR013320; ","\"Galectin, carbohydrate recognition domain; Concanavalin A-like lectin/glucanase domain; \"\r"]
["P09417","Dihydropteridine reductase OS=Homo sapiens OX=9606 GN=QDPR","QDPR",25.789,47.66,43.9,7,11,7,1.086,1.092,1.055,0.949,0.944,0.9,0.864,0.00184,"cytoplasm\r","GO:0051188 cofactor biosynthetic process; GO:1902222 erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process; GO:0042559 pteridine-containing compound biosynthetic process; GO:1901606 alpha-amino acid catabolic process; GO:0048732 gland development; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0006559 L-phenylalanine catabolic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0009719 response to endogenous stimulus; GO:1901361 organic cyclic compound catabolic process; GO:0009108 coenzyme biosynthetic process; GO:0010035 response to inorganic substance; GO:1901652 response to peptide; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0009072 aromatic amino acid family metabolic process; GO:0018130 heterocycle biosynthetic process; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0006732 coenzyme metabolic process; GO:0032501 multicellular organismal process; GO:0010038 response to metal ion; GO:0051186 cofactor metabolic process; GO:0046395 carboxylic acid catabolic process; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0010243 response to organonitrogen compound; GO:0048513 animal organ development; GO:0042221 response to chemical; GO:0043434 response to peptide hormone; GO:0044710 single-organism metabolic process; GO:1901698 response to nitrogen compound; GO:0010288 response to lead ion; GO:0009063 cellular amino acid catabolic process; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:1901362 organic cyclic compound biosynthetic process; GO:0043436 oxoacid metabolic process; GO:0010044 response to aluminum ion; GO:0044707 single-multicellular organism process; GO:0035690 cellular response to drug; GO:0006725 cellular aromatic compound metabolic process; GO:1901700 response to oxygen-containing compound; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0042493 response to drug; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006729 tetrahydrobiopterin biosynthetic process; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0046146 tetrahydrobiopterin metabolic process; GO:0061008 hepaticobiliary system development; GO:0007275 multicellular organism development; GO:1902221 erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process; GO:0009987 cellular process; GO:0009074 aromatic amino acid family catabolic process; GO:0044712 single-organism catabolic process; GO:0048731 system development; GO:0051066 dihydrobiopterin metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044282 small molecule catabolic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901605 alpha-amino acid metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0042558 pteridine-containing compound metabolic process; GO:0006558 L-phenylalanine metabolic process; GO:0001889 liver development; GO:1901565 organonitrogen compound catabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0044767 single-organism developmental process; GO:0019752 carboxylic acid metabolic process; GO:0016054 organic acid catabolic process; GO:0033762 response to glucagon; GO:0009725 response to hormone; GO:0009056 catabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors; GO:1901265 nucleoside phosphate binding; GO:0046983 protein dimerization activity; GO:0070402 NADPH binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0004155 6,7-dihydropteridine reductase activity; GO:0048037 cofactor binding; GO:0070404 NADH binding; GO:0016491 oxidoreductase activity; GO:0009055 electron carrier activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0042802 identical protein binding; GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor; GO:0051287 NAD binding; GO:0003824 catalytic activity; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0050661 NADP binding; GO:0043168 anion binding; GO:0050662 coenzyme binding; GO:0036094 small molecule binding; ","K00357","QDPR; dihydropteridine reductase [EC:1.5.1.34]","hsa00790 Folate biosynthesis - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR016040; ","NAD(P)-binding domain; \r"]
["P09429","High mobility group protein B1 OS=Homo sapiens OX=9606 GN=HMGB1","HMGB1",24.893,44.807,29.8,6,9,5,0.879,0.837,0.846,1.136,1.121,1.125,1.32,5.76e-05,"nucleus\r",{"$cut":{"chars":24603,"head":"GO:0044700 single organism signaling; GO:0002694 regulation of leukocyte activation; GO:0010941 regulation of cell death; GO:0032872 regulation of stress-activated MAPK cascade; GO:0006266 DNA ligation; GO:0002292 T cell differentiation involved in immune response; GO:0009891 positive regulation of biosynthetic process; GO:0031347 regulation of defense response; GO:0006914 autophagy; GO:0044237 cellular metabolic process; GO:0010594 regulation of endothelial cell migration; GO:0042110 T cell activation; GO:0032732 positive regulation of interleukin-1 production; GO:0008152 metabolic process; GO:0032946 positive regulation of mononuclear cell proliferation; GO:0044093 positive regulation of molecular function; GO:0055065 metal ion homeostasis; GO:2000515 negative regulation of CD4-positive, alpha-beta T cell activation; GO:0043370 regulation of CD4-positive, alpha-beta T cell differentiation; GO:0009306 protein secretion; GO:0071706 tumor necrosis factor superfamily cytokine production; GO:0051099 positive regulation of binding; GO:0031333 negative regulation of protein complex assembly; GO:0002709 regulation of T cell mediated immunity; GO:0052548 regulation of endopeptidase activity; GO:0046636 negative regulation of alpha-beta T cell activation; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0010950 positive regulation of endopeptidase activity; GO:0051054 positive regulation of DNA metabolic process; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:1903038 negative regulation of leukocyte cell-cell adhesion; GO:0044763 single-organism cellular process; GO:0046006 regulation of activated T cell proliferation; GO:0002520 immune system development; GO:0048870 cell motility; GO:0006935 chemotaxis; GO:0010506 regulation of autophagy; GO:0006874 cellular calcium ion homeostasis; GO:0051106 positive regulation of DNA ligation; GO:0050776 regulation of immune response; GO:0001773 myeloid dendritic cell activation; GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0080135 regulation of cellular response to stress; GO:0032874 positive regulation of stress-activated MAPK cascade; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0043367 CD4-positive, alpha-beta T cell differentiation; GO:0051223 regulation of protein transport; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0090305 nucleic acid phosphodiester bond hydrolysis; GO:0071675 regulation of mononuclear cell migration; GO:0002687 positive regulation of leukocyte migration; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0044707 single-multicellular organism process; GO:2001056 positive regulation of cysteine-type endopeptidase activity; GO:0045580 regulation of T cell differentiation; GO:0001819 positive regulation of cytokine production; GO:0006259 DNA metabolic process; GO:0022408 negative regulation of cell-cell adhesion; GO:0048519 negative regulation of biological process; GO:1903706 regulation of hemopoiesis; GO:2000778 positive regulation of interleukin-6 secretion; GO:0030098 lymphocyte differentiation; GO:0045892 negative regulation of transcription, DNA-templated; GO:0044270 cellular nitrogen compound catabolic process; GO:0050867 positive regulation of cell activation; GO:0046483 heterocycle metabolic process; GO:0051345 positive regulation of hydrolase activity; GO:0006139 nucleobase-containing compound metabolic process; GO:0050716 positive regulation of interleukin-1 secretion; GO:0009889 regulation of biosynthetic process; GO:2000145 regulation of cell motility; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:0042093 T-helper cell differentiation; GO:0044248 cellular catabolic process; GO:1902680 positive regulation of RNA bi"}},"GO:0034774 secretory granule lumen; GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0000793 condensed chromosome; GO:0031974 membrane-enclosed lumen; GO:0101002 ficolin-1-rich granule; GO:0031983 vesicle lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0099503 secretory vesicle; GO:0005768 endosome; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0005793 endoplasmic reticulum-Golgi intermediate compartment; GO:0009986 cell surface; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005102 receptor binding; GO:0070182 DNA polymerase binding; GO:0003690 double-stranded DNA binding; GO:0019958 C-X-C chemokine binding; GO:0003697 single-stranded DNA binding; GO:0005515 protein binding; GO:0019956 chemokine binding; GO:0000217 DNA secondary structure binding; GO:0003700 transcription factor activity, sequence-specific DNA binding; GO:0001786 phosphatidylserine binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0000405 bubble DNA binding; GO:0005125 cytokine activity; GO:0050786 RAGE receptor binding; GO:0070491 repressing transcription factor binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0001071 nucleic acid binding transcription factor activity; GO:0008289 lipid binding; GO:0003684 damaged DNA binding; GO:0043168 anion binding; GO:0097100 supercoiled DNA binding; GO:0000400 four-way junction DNA binding; GO:0003723 RNA binding; GO:0003677 DNA binding; GO:0043167 ion binding; GO:0016829 lyase activity; GO:0042056 chemoattractant activity; GO:0019955 cytokine binding; GO:0097367 carbohydrate derivative binding; GO:0072341 modified amino acid binding; GO:0003676 nucleic acid binding; GO:0005543 phospholipid binding; GO:0001530 lipopolysaccharide binding; GO:0008301 DNA binding, bending; GO:0019899 enzyme binding; GO:0008134 transcription factor binding; ","K10802","HMGB1; high mobility group protein B1","hsa04217 Necroptosis - Homo sapiens (human); hsa03410 Base excision repair - Homo sapiens (human); hsa04140 Autophagy - animal - Homo sapiens (human); ","IPR009071; ","High mobility group box domain; \r"]
["P09455","Retinol-binding protein 1 OS=Homo sapiens OX=9606 GN=RBP1","RBP1",15.85,9.0749,15.6,2,2,2,1.114,1.087,0.993,0.885,0.918,1.02,0.884,0.0873,"cytoplasm\r","GO:0065008 regulation of biological quality; GO:0016053 organic acid biosynthetic process; GO:0042573 retinoic acid metabolic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0009058 biosynthetic process; GO:0006776 vitamin A metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008610 lipid biosynthetic process; GO:0051234 establishment of localization; GO:0006775 fat-soluble vitamin metabolic process; GO:0008299 isoprenoid biosynthetic process; GO:0006766 vitamin metabolic process; GO:0008152 metabolic process; GO:0001523 retinoid metabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0016114 terpenoid biosynthetic process; GO:0009987 cellular process; GO:0006629 lipid metabolic process; GO:0006720 isoprenoid metabolic process; GO:0042445 hormone metabolic process; GO:0044711 single-organism biosynthetic process; GO:0016102 diterpenoid biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0034754 cellular hormone metabolic process; GO:0006810 transport; GO:0046394 carboxylic acid biosynthetic process; GO:0002138 retinoic acid biosynthetic process; GO:0044710 single-organism metabolic process; GO:0044283 small molecule biosynthetic process; GO:0019752 carboxylic acid metabolic process; GO:0010817 regulation of hormone levels; GO:0006721 terpenoid metabolic process; GO:0016101 diterpenoid metabolic process; GO:0006082 organic acid metabolic process; GO:0051179 localization; GO:0072330 monocarboxylic acid biosynthetic process; GO:0043436 oxoacid metabolic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0019842 vitamin binding; GO:0005488 binding; GO:0043178 alcohol binding; GO:0019841 retinol binding; GO:0005501 retinoid binding; GO:0008289 lipid binding; GO:0019840 isoprenoid binding; GO:0016918 retinal binding; GO:0005215 transporter activity; GO:0036094 small molecule binding; ",{"$nulls":3},"IPR000463; IPR000566; IPR012674; IPR011038; ","Cytosolic fatty-acid binding; Lipocalin/cytosolic fatty-acid binding domain; Calycin; Calycin-like; \r"]
["P09467","Fructose-1,6-bisphosphatase 1 OS=Homo sapiens OX=9606 GN=FBP1","FBP1",36.842,37.345,19.8,5,5,5,1.284,1.209,1.206,0.693,0.884,0.759,0.632,0.00328,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0071286 cellular response to magnesium ion; GO:0045980 negative regulation of nucleotide metabolic process; GO:0006002 fructose 6-phosphate metabolic process; GO:0044237 cellular metabolic process; GO:0006006 glucose metabolic process; GO:0001558 regulation of cell growth; GO:0045978 negative regulation of nucleoside metabolic process; GO:0008152 metabolic process; GO:0006094 gluconeogenesis; GO:0044262 cellular carbohydrate metabolic process; GO:0005985 sucrose metabolic process; GO:0065003 macromolecular complex assembly; GO:0034637 cellular carbohydrate biosynthetic process; GO:0051056 regulation of small GTPase mediated signal transduction; GO:0010677 negative regulation of cellular carbohydrate metabolic process; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:0009894 regulation of catabolic process; GO:0051198 negative regulation of coenzyme metabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0031323 regulation of cellular metabolic process; GO:0005975 carbohydrate metabolic process; GO:0006000 fructose metabolic process; GO:1902532 negative regulation of intracellular signal transduction; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:0046351 disaccharide biosynthetic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0006140 regulation of nucleotide metabolic process; GO:0030388 fructose 1,6-bisphosphate metabolic process; GO:0050794 regulation of cellular process; GO:0043255 regulation of carbohydrate biosynthetic process; GO:0006111 regulation of gluconeogenesis; GO:0051260 protein homooligomerization; GO:0046364 monosaccharide biosynthetic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0010906 regulation of glucose metabolic process; GO:0051259 protein oligomerization; GO:0042493 response to drug; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0009966 regulation of signal transduction; GO:0006461 protein complex assembly; GO:0046580 negative regulation of Ras protein signal transduction; GO:1902531 regulation of intracellular signal transduction; GO:0044711 single-organism biosynthetic process; GO:1903579 negative regulation of ATP metabolic process; GO:0009312 oligosaccharide biosynthetic process; GO:0044238 primary metabolic process; GO:0006109 regulation of carbohydrate metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0045912 negative regulation of carbohydrate metabolic process; GO:0006793 phosphorus metabolic process; GO:1900543 negative regulation of purine nucleotide metabolic process; GO:0044283 small molecule biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0071248 cellular response to metal ion; GO:0045936 negative regulation of phosphate metabolic process; GO:0019318 hexose metabolic process; GO:0043467 regulation of generation of precursor metabolites and energy; GO:0032026 response to magnesium ion; GO:0009968 negative regulation of signal transduction; GO:0019319 hexose biosynthetic process; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0005984 disaccharide metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051196 regulation of coenzyme metabolic process; GO:0010646 regulation of cell communication; GO:0051262 protein tetramerization; GO:0022607 cellular component assembly; GO:0010035 response to inorganic substance; GO:0070887 cellular response to chemical stimulus; GO:0051193 regulation of cofactor metabolic process; GO:0045926 negative regulation of growth; GO:0071822 protein complex subunit organization; GO:0010675 regulation of cellular carbohydrate metabolic process; GO:0006110 regulation of glycolytic process; GO:0043470 regulation of carbohydrate catabolic process; GO:0010038 response to metal ion; GO:0030308 negative regulation of cell growth; GO:0044723 single-organism carbohydrate metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0071241 cellular response to inorganic substance; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0070271 protein complex biogenesis; GO:0051195 negative regulation of cofactor metabolic process; GO:0005986 sucrose biosynthetic process; GO:0016043 cellular component organization; GO:0035690 cellular response to drug; GO:0016051 carbohydrate biosynthetic process; GO:0040008 regulation of growth; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0009118 regulation of nucleoside metabolic process; GO:0046578 regulation of Ras protein signal transduction; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0051289 protein homotetramerization; GO:0042326 negative regulation of phosphorylation; GO:0005996 monosaccharide metabolic process; GO:0009895 negative regulation of catabolic process; GO:0009311 oligosaccharide metabolic process; GO:0009987 cellular process; GO:0045820 negative regulation of glycolytic process; GO:1903578 regulation of ATP metabolic process; GO:0048585 negative regulation of response to stimulus; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0016311 dephosphorylation; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:1900542 regulation of purine nucleotide metabolic process; GO:0010563 negative regulation of phosphorus metabolic process; GO:0051128 regulation of cellular component organization; GO:0051058 negative regulation of small GTPase mediated signal transduction; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0016791 phosphatase activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0048029 monosaccharide binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016208 AMP binding; GO:0042802 identical protein binding; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0050308 sugar-phosphatase activity; GO:0017076 purine nucleotide binding; GO:0019203 carbohydrate phosphatase activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0042578 phosphoric ester hydrolase activity; GO:0016788 hydrolase activity, acting on ester bonds; GO:0046872 metal ion binding; GO:0030246 carbohydrate binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; ","K03841","FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]","hsa00051 Fructose and mannose metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa04922 Glucagon signaling pathway - Homo sapiens (human); hsa04910 Insulin signaling pathway - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); hsa04152 AMPK signaling pathway - Homo sapiens (human); hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human); hsa00030 Pentose phosphate pathway - Homo sapiens (human); ","IPR033391; ","\"Fructose-1-6-bisphosphatase class I, N-terminal; \"\r"]
["P09486","SPARC OS=Homo sapiens OX=9606 GN=SPARC","SPARC",34.632,50.372,29.4,8,12,8,1.223,1.19,1.096,0.818,0.888,0.906,0.744,0.0029,"extracellular\r","GO:0044700 single organism signaling; GO:0030335 positive regulation of cell migration; GO:0030323 respiratory tube development; GO:0046683 response to organophosphorus; GO:0010594 regulation of endothelial cell migration; GO:0009607 response to biotic stimulus; GO:0008285 negative regulation of cell proliferation; GO:0009605 response to external stimulus; GO:0007507 heart development; GO:0051240 positive regulation of multicellular organismal process; GO:0050678 regulation of epithelial cell proliferation; GO:0032879 regulation of localization; GO:0048545 response to steroid hormone; GO:0009719 response to endogenous stimulus; GO:0070848 response to growth factor; GO:0009743 response to carbohydrate; GO:1901652 response to peptide; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0010632 regulation of epithelial cell migration; GO:0001503 ossification; GO:0044763 single-organism cellular process; GO:0051272 positive regulation of cellular component movement; GO:1901343 negative regulation of vasculature development; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0010243 response to organonitrogen compound; GO:0048513 animal organ development; GO:0043583 ear development; GO:0051591 response to cAMP; GO:0034284 response to monosaccharide; GO:1901698 response to nitrogen compound; GO:0045765 regulation of angiogenesis; GO:0072359 circulatory system development; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0042127 regulation of cell proliferation; GO:0009628 response to abiotic stimulus; GO:0009629 response to gravity; GO:1901700 response to oxygen-containing compound; GO:0002576 platelet degranulation; GO:2000147 positive regulation of cell motility; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0051239 regulation of multicellular organismal process; GO:0033591 response to L-ascorbic acid; GO:1902578 single-organism localization; GO:0014074 response to purine-containing compound; GO:0060541 respiratory system development; GO:0043062 extracellular structure organization; GO:2000145 regulation of cell motility; GO:0006898 receptor-mediated endocytosis; GO:0007275 multicellular organism development; GO:0001936 regulation of endothelial cell proliferation; GO:0009617 response to bacterium; GO:0006950 response to stress; GO:0032496 response to lipopolysaccharide; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0097305 response to alcohol; GO:0030334 regulation of cell migration; GO:0010033 response to organic substance; GO:0048839 inner ear development; GO:0007584 response to nutrient; GO:0060348 bone development; GO:0045055 regulated exocytosis; GO:0043473 pigmentation; GO:0007423 sensory organ development; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0006887 exocytosis; GO:0051093 negative regulation of developmental process; GO:0001101 response to acid chemical; GO:0040017 positive regulation of locomotion; GO:0044699 single-organism process; GO:0051241 negative regulation of multicellular organismal process; GO:0071363 cellular response to growth factor stimulus; GO:0051234 establishment of localization; GO:0009611 response to wounding; GO:0001937 negative regulation of endothelial cell proliferation; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0046686 response to cadmium ion; GO:0010035 response to inorganic substance; GO:0030198 extracellular matrix organization; GO:0070887 cellular response to chemical stimulus; GO:0033273 response to vitamin; GO:0032502 developmental process; GO:0030324 lung development; GO:2000181 negative regulation of blood vessel morphogenesis; GO:0035295 tube development; GO:0034097 response to cytokine; GO:0002237 response to molecule of bacterial origin; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0010038 response to metal ion; GO:0051384 response to glucocorticoid; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0016525 negative regulation of angiogenesis; GO:0043434 response to peptide hormone; GO:0032940 secretion by cell; GO:0010288 response to lead ion; GO:0050680 negative regulation of epithelial cell proliferation; GO:0048856 anatomical structure development; GO:0001501 skeletal system development; GO:2000026 regulation of multicellular organismal development; GO:0016043 cellular component organization; GO:0010595 positive regulation of endothelial cell migration; GO:0071310 cellular response to organic substance; GO:0045471 response to ethanol; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0009991 response to extracellular stimulus; GO:0033993 response to lipid; GO:0031960 response to corticosteroid; GO:0051592 response to calcium ion; GO:0009987 cellular process; GO:1901342 regulation of vasculature development; GO:0010634 positive regulation of epithelial cell migration; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0042060 wound healing; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0051128 regulation of cellular component organization; GO:0031667 response to nutrient levels; GO:0040012 regulation of locomotion; GO:0009725 response to hormone; GO:0022604 regulation of cell morphogenesis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0034774 secretory granule lumen; GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044420 extracellular matrix component; GO:0044422 organelle part; GO:0005604 basement membrane; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0099503 secretory vesicle; GO:0030141 secretory granule; GO:0030139 endocytic vesicle; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0031092 platelet alpha granule membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0005576 extracellular region; GO:0030659 cytoplasmic vesicle membrane; GO:0031012 extracellular matrix; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0030667 secretory granule membrane; GO:0060205 cytoplasmic vesicle lumen; GO:0016363 nuclear matrix; GO:0005578 proteinaceous extracellular matrix; GO:0031093 platelet alpha granule lumen; GO:0009986 cell surface; GO:0034399 nuclear periphery; GO:0031091 platelet alpha granule; GO:0044444 cytoplasmic part; GO:0071682 endocytic vesicle lumen; GO:0044428 nuclear part; ","GO:0005488 binding; GO:0043167 ion binding; GO:0044877 macromolecular complex binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0005518 collagen binding; GO:0005509 calcium ion binding; GO:0050840 extracellular matrix binding; GO:0032403 protein complex binding; ",{"$nulls":3},"IPR002350; IPR011992; IPR019577; IPR015369; IPR003645; ","\"Kazal domain; EF-hand domain pair; SPARC/Testican, calcium-binding domain; Follistatin/Osteonectin EGF domain; Follistatin-like, N-terminal; \"\r"]
["P09493","Tropomyosin alpha-1 chain OS=Homo sapiens OX=9606 GN=TPM1","TPM1",32.708,37.959,55.3,23,31,10,1.223,1.138,1.202,0.814,0.826,0.837,0.695,9.82e-05,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0045777 positive regulation of blood pressure; GO:0003065 positive regulation of heart rate by epinephrine; GO:0043009 chordate embryonic development; GO:0060415 muscle tissue morphogenesis; GO:0032989 cellular component morphogenesis; GO:0008285 negative regulation of cell proliferation; GO:0030036 actin cytoskeleton organization; GO:0007507 heart development; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0008360 regulation of cell shape; GO:0044093 positive regulation of molecular function; GO:0003208 cardiac ventricle morphogenesis; GO:0044057 regulation of system process; GO:0051493 regulation of cytoskeleton organization; GO:0009790 embryo development; GO:0003044 regulation of systemic arterial blood pressure mediated by a chemical signal; GO:0051716 cellular response to stimulus; GO:0060537 muscle tissue development; GO:0000302 response to reactive oxygen species; GO:0055008 cardiac muscle tissue morphogenesis; GO:0044763 single-organism cellular process; GO:0006941 striated muscle contraction; GO:1904753 negative regulation of vascular associated smooth muscle cell migration; GO:2000146 negative regulation of cell motility; GO:0032501 multicellular organismal process; GO:0010460 positive regulation of heart rate; GO:0048513 animal organ development; GO:0003229 ventricular cardiac muscle tissue development; GO:0051336 regulation of hydrolase activity; GO:0055002 striated muscle cell development; GO:0001701 in utero embryonic development; GO:0050790 regulation of catalytic activity; GO:0048644 muscle organ morphogenesis; GO:0009887 animal organ morphogenesis; GO:0032781 positive regulation of ATPase activity; GO:1902905 positive regulation of supramolecular fiber organization; GO:1904705 regulation of vascular smooth muscle cell proliferation; GO:0014912 negative regulation of smooth muscle cell migration; GO:1904752 regulation of vascular associated smooth muscle cell migration; GO:0032233 positive regulation of actin filament bundle assembly; GO:0003015 heart process; GO:0003013 circulatory system process; GO:0097435 supramolecular fiber organization; GO:1902903 regulation of supramolecular fiber organization; GO:0055001 muscle cell development; GO:0050794 regulation of cellular process; GO:0072359 circulatory system development; GO:0033554 cellular response to stress; GO:0044707 single-multicellular organism process; GO:0030049 muscle filament sliding; GO:0042127 regulation of cell proliferation; GO:0032956 regulation of actin cytoskeleton organization; GO:1901700 response to oxygen-containing compound; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0051239 regulation of multicellular organismal process; GO:0031529 ruffle organization; GO:0009653 anatomical structure morphogenesis; GO:0051345 positive regulation of hydrolase activity; GO:0055010 ventricular cardiac muscle tissue morphogenesis; GO:0030239 myofibril assembly; GO:2000145 regulation of cell motility; GO:0061061 muscle structure development; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0003231 cardiac ventricle development; GO:0001993 regulation of systemic arterial blood pressure by norepinephrine-epinephrine; GO:0051495 positive regulation of cytoskeleton organization; GO:0045785 positive regulation of cell adhesion; GO:0006950 response to stress; GO:0051270 regulation of cellular component movement; GO:0032231 regulation of actin filament bundle assembly; GO:0048731 system development; GO:0010927 cellular component assembly involved in morphogenesis; GO:0032970 regulation of actin filament-based process; GO:0030334 regulation of cell migration; GO:0003206 cardiac chamber morphogenesis; GO:0030155 regulation of cell adhesion; GO:0051492 regulation of stress fiber assembly; GO:0030336 negative regulation of cell migration; GO:0006996 organelle organization; GO:0002027 regulation of heart rate; GO:0030029 actin filament-based process; GO:0051496 positive regulation of stress fiber assembly; GO:0006928 movement of cell or subcellular component; GO:0050793 regulation of developmental process; GO:0030048 actin filament-based movement; GO:0003012 muscle system process; GO:0070252 actin-mediated cell contraction; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0051130 positive regulation of cellular component organization; GO:0009611 response to wounding; GO:0040013 negative regulation of locomotion; GO:0048729 tissue morphogenesis; GO:0022607 cellular component assembly; GO:0003073 regulation of systemic arterial blood pressure; GO:0006979 response to oxidative stress; GO:0003062 regulation of heart rate by chemical signal; GO:0034599 cellular response to oxidative stress; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0031032 actomyosin structure organization; GO:0034614 cellular response to reactive oxygen species; GO:0009888 tissue development; GO:0003007 heart morphogenesis; GO:0048522 positive regulation of cellular process; GO:0090257 regulation of muscle system process; GO:1904706 negative regulation of vascular smooth muscle cell proliferation; GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine; GO:1902589 single-organism organelle organization; GO:0045214 sarcomere organization; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0043462 regulation of ATPase activity; GO:0010638 positive regulation of organelle organization; GO:0030030 cell projection organization; GO:0007517 muscle organ development; GO:0065009 regulation of molecular function; GO:0048856 anatomical structure development; GO:0051271 negative regulation of cellular component movement; GO:0014706 striated muscle tissue development; GO:0008217 regulation of blood pressure; GO:0016043 cellular component organization; GO:0048738 cardiac muscle tissue development; GO:0048660 regulation of smooth muscle cell proliferation; GO:1903522 regulation of blood circulation; GO:0007015 actin filament organization; GO:0044087 regulation of cellular component biogenesis; GO:0060048 cardiac muscle contraction; GO:0008016 regulation of heart contraction; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0030154 cell differentiation; GO:0006936 muscle contraction; GO:0070925 organelle assembly; GO:0008015 blood circulation; GO:0060047 heart contraction; GO:1903524 positive regulation of blood circulation; GO:0009987 cellular process; GO:0051146 striated muscle cell differentiation; GO:0003008 system process; GO:0033275 actin-myosin filament sliding; GO:0009792 embryo development ending in birth or egg hatching; GO:0006937 regulation of muscle contraction; GO:0033043 regulation of organelle organization; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0003205 cardiac chamber development; GO:0048662 negative regulation of smooth muscle cell proliferation; GO:1901701 cellular response to oxygen-containing compound; GO:0042060 wound healing; GO:0045823 positive regulation of heart contraction; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0042692 muscle cell differentiation; GO:0051128 regulation of cellular component organization; GO:0040012 regulation of locomotion; GO:0003321 positive regulation of blood pressure by epinephrine-norepinephrine; GO:0022604 regulation of cell morphogenesis; GO:0044089 positive regulation of cellular component biogenesis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:0014910 regulation of smooth muscle cell migration; ","GO:0016020 membrane; GO:0071944 cell periphery; GO:0030016 myofibril; GO:0032587 ruffle membrane; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0099512 supramolecular fiber; GO:0032059 bleb; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0032432 actin filament bundle; GO:0044422 organelle part; GO:0005862 muscle thin filament tropomyosin; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0098590 plasma membrane region; GO:0031256 leading edge membrane; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0043292 contractile fiber; GO:0005884 actin filament; GO:0005865 striated muscle thin filament; GO:0001725 stress fiber; GO:0042641 actomyosin; GO:0031941 filamentous actin; GO:0031252 cell leading edge; GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0097517 contractile actin filament bundle; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0015629 actin cytoskeleton; GO:0036379 myofilament; GO:0005886 plasma membrane; GO:0099081 supramolecular polymer; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0030017 sarcomere; GO:0044449 contractile fiber part; GO:0001726 ruffle; GO:0031253 cell projection membrane; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0051015 actin filament binding; GO:0008092 cytoskeletal protein binding; GO:0005200 structural constituent of cytoskeleton; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0003779 actin binding; GO:0005515 protein binding; GO:0008307 structural constituent of muscle; GO:0005198 structural molecule activity; GO:0032403 protein complex binding; ","K10373","TPM1; tropomyosin 1","hsa04260 Cardiac muscle contraction - Homo sapiens (human); hsa05414 Dilated cardiomyopathy (DCM) - Homo sapiens (human); hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human); hsa05206 MicroRNAs in cancer - Homo sapiens (human); hsa05410 Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human); "]
["P09496","Clathrin light chain A OS=Homo sapiens OX=9606 GN=CLTA","CLTA",27.076,10.828,22.2,7,10,7,0.996,1.054,1.077,0.944,0.95,0.97,0.916,0.0241,"cytoplasm\r","GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0007067 mitotic nuclear division; GO:0048285 organelle fission; GO:0044699 single-organism process; GO:1903047 mitotic cell cycle process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0051649 establishment of localization in cell; GO:0072583 clathrin-dependent endocytosis; GO:0006886 intracellular protein transport; GO:0006898 receptor-mediated endocytosis; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0034613 cellular protein localization; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0009987 cellular process; GO:0000278 mitotic cell cycle; GO:0048002 antigen processing and presentation of peptide antigen; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0002376 immune system process; GO:0071702 organic substance transport; GO:0006897 endocytosis; GO:0002495 antigen processing and presentation of peptide antigen via MHC class II; GO:0007017 microtubule-based process; GO:0051641 cellular localization; GO:0006810 transport; GO:0045184 establishment of protein localization; GO:0019882 antigen processing and presentation; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0007018 microtubule-based movement; GO:0070727 cellular macromolecule localization; GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0006928 movement of cell or subcellular component; GO:0000280 nuclear division; GO:0051301 cell division; GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II; GO:0022402 cell cycle process; GO:0051179 localization; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0032588 trans-Golgi network membrane; GO:0036019 endolysosome; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005765 lysosomal membrane; GO:0030136 clathrin-coated vesicle; GO:0005622 intracellular; GO:0005764 lysosome; GO:0098589 membrane region; GO:0098791 Golgi subcompartment; GO:0012510 trans-Golgi network transport vesicle membrane; GO:0043227 membrane-bounded organelle; GO:0000323 lytic vacuole; GO:0010008 endosome membrane; GO:0044430 cytoskeletal part; GO:0036020 endolysosome membrane; GO:0048475 coated membrane; GO:0098797 plasma membrane protein complex; GO:0044440 endosomal part; GO:0012506 vesicle membrane; GO:0030135 coated vesicle; GO:0005798 Golgi-associated vesicle; GO:0005886 plasma membrane; GO:0030125 clathrin vesicle coat; GO:0043231 intracellular membrane-bounded organelle; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0030118 clathrin coat; GO:0030117 membrane coat; GO:0005905 clathrin-coated pit; GO:0043234 protein complex; GO:0030133 transport vesicle; GO:0030658 transport vesicle membrane; GO:0030130 clathrin coat of trans-Golgi network vesicle; GO:0031410 cytoplasmic vesicle; GO:0098796 membrane protein complex; GO:0071944 cell periphery; GO:0030660 Golgi-associated vesicle membrane; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0030120 vesicle coat; GO:0030662 coated vesicle membrane; GO:0005856 cytoskeleton; GO:0030140 trans-Golgi network transport vesicle; GO:0015630 microtubule cytoskeleton; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0044431 Golgi apparatus part; GO:0005768 endosome; GO:0030132 clathrin coat of coated pit; GO:0071439 clathrin complex; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005819 spindle; GO:0030665 clathrin-coated vesicle membrane; GO:0098852 lytic vacuole membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0005802 trans-Golgi network; GO:0005774 vacuolar membrane; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; GO:0031984 organelle subcompartment; ","GO:0030276 clathrin binding; GO:0042277 peptide binding; GO:0005488 binding; GO:0032050 clathrin heavy chain binding; GO:0005515 protein binding; GO:0033218 amide binding; GO:0005198 structural molecule activity; ","K04644","CLTA; clathrin light chain A","hsa04142 Lysosome - Homo sapiens (human); hsa05100 Bacterial invasion of epithelial cells - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04144 Endocytosis - Homo sapiens (human); hsa04961 Endocrine and other factor-regulated calcium reabsorption - Homo sapiens (human); hsa04721 Synaptic vesicle cycle - Homo sapiens (human); "]
["P09497","Clathrin light chain B OS=Homo sapiens OX=9606 GN=CLTB","CLTB",25.19,20.512,27.5,8,11,8,0.964,0.953,1.06,1.001,0.979,1.061,1.021,0.626,"cytoplasm\r","GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0016192 vesicle-mediated transport; GO:0071702 organic substance transport; GO:0006897 endocytosis; GO:0015031 protein transport; GO:0051641 cellular localization; GO:0051234 establishment of localization; GO:0006810 transport; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0072583 clathrin-dependent endocytosis; GO:0051649 establishment of localization in cell; GO:0061024 membrane organization; GO:0006886 intracellular protein transport; GO:0006898 receptor-mediated endocytosis; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0034613 cellular protein localization; GO:0051179 localization; GO:0009987 cellular process; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0098590 plasma membrane region; GO:0030136 clathrin-coated vesicle; GO:0005622 intracellular; GO:0098589 membrane region; GO:0098791 Golgi subcompartment; GO:0012510 trans-Golgi network transport vesicle membrane; GO:0043227 membrane-bounded organelle; GO:0005929 cilium; GO:0042995 cell projection; GO:0048475 coated membrane; GO:0098797 plasma membrane protein complex; GO:0012506 vesicle membrane; GO:0030135 coated vesicle; GO:0005798 Golgi-associated vesicle; GO:0005886 plasma membrane; GO:0030125 clathrin vesicle coat; GO:0043231 intracellular membrane-bounded organelle; GO:0030118 clathrin coat; GO:0030117 membrane coat; GO:0005905 clathrin-coated pit; GO:0043234 protein complex; GO:0030133 transport vesicle; GO:0060170 ciliary membrane; GO:0030658 transport vesicle membrane; GO:0030130 clathrin coat of trans-Golgi network vesicle; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0030660 Golgi-associated vesicle membrane; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0030120 vesicle coat; GO:0030662 coated vesicle membrane; GO:0030140 trans-Golgi network transport vesicle; GO:0044441 ciliary part; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0044431 Golgi apparatus part; GO:0030132 clathrin coat of coated pit; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044463 cell projection part; GO:0005829 cytosol; GO:0030665 clathrin-coated vesicle membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0005802 trans-Golgi network; GO:0031253 cell projection membrane; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; GO:0031984 organelle subcompartment; ","GO:0030276 clathrin binding; GO:0042277 peptide binding; GO:0005488 binding; GO:0032050 clathrin heavy chain binding; GO:0005515 protein binding; GO:0033218 amide binding; GO:0005198 structural molecule activity; ","K04645","CLTB; clathrin light chain B","hsa04142 Lysosome - Homo sapiens (human); hsa05100 Bacterial invasion of epithelial cells - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04144 Endocytosis - Homo sapiens (human); hsa04961 Endocrine and other factor-regulated calcium reabsorption - Homo sapiens (human); hsa04721 Synaptic vesicle cycle - Homo sapiens (human); "]
["P09525","Annexin A4 OS=Homo sapiens OX=9606 GN=ANXA4","ANXA4",35.882,271.15,65.8,24,57,24,1.161,1.105,1.094,0.903,0.889,0.899,0.801,0.000303,"cytoplasm\r","GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity; GO:0007166 cell surface receptor signaling pathway; GO:0048869 cellular developmental process; GO:0051241 negative regulation of multicellular organismal process; GO:0051046 regulation of secretion; GO:0044699 single-organism process; GO:0001818 negative regulation of cytokine production; GO:0050710 negative regulation of cytokine secretion; GO:0032088 negative regulation of NF-kappaB transcription factor activity; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0032879 regulation of localization; GO:2000483 negative regulation of interleukin-8 secretion; GO:0007219 Notch signaling pathway; GO:0032502 developmental process; GO:0051051 negative regulation of transport; GO:0060429 epithelium development; GO:0010468 regulation of gene expression; GO:0051716 cellular response to stimulus; GO:0050709 negative regulation of protein secretion; GO:0009888 tissue development; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:1903531 negative regulation of secretion by cell; GO:0050707 regulation of cytokine secretion; GO:1903530 regulation of secretion by cell; GO:0023052 signaling; GO:0031323 regulation of cellular metabolic process; GO:0043086 negative regulation of catalytic activity; GO:2000482 regulation of interleukin-8 secretion; GO:1903506 regulation of nucleic acid-templated transcription; GO:0051048 negative regulation of secretion; GO:0050789 regulation of biological process; GO:0050790 regulation of catalytic activity; GO:0051090 regulation of sequence-specific DNA binding transcription factor activity; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0051223 regulation of protein transport; GO:0044092 negative regulation of molecular function; GO:0048856 anatomical structure development; GO:0060548 negative regulation of cell death; GO:0030855 epithelial cell differentiation; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0032677 regulation of interleukin-8 production; GO:0043069 negative regulation of programmed cell death; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0043067 regulation of programmed cell death; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:0070201 regulation of establishment of protein localization; GO:0051239 regulation of multicellular organismal process; GO:0030154 cell differentiation; GO:0043066 negative regulation of apoptotic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0032880 regulation of protein localization; GO:0050708 regulation of protein secretion; GO:0032717 negative regulation of interleukin-8 production; GO:0009987 cellular process; GO:0006355 regulation of transcription, DNA-templated; GO:0051224 negative regulation of protein transport; GO:0051049 regulation of transport; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0044767 single-organism developmental process; GO:0001817 regulation of cytokine production; GO:1904950 negative regulation of establishment of protein localization; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005635 nuclear envelope; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0031965 nuclear membrane; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:0031975 envelope; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0009986 cell surface; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005544 calcium-dependent phospholipid binding; GO:0055102 lipase inhibitor activity; GO:0043167 ion binding; GO:0004859 phospholipase inhibitor activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0004857 enzyme inhibitor activity; GO:0048306 calcium-dependent protein binding; GO:0042802 identical protein binding; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0005543 phospholipid binding; GO:0008289 lipid binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0043168 anion binding; GO:0051059 NF-kappaB binding; GO:0005509 calcium ion binding; GO:0008134 transcription factor binding; ","K17093"]
["P09543","2',3'-cyclic-nucleotide 3'-phosphodiesterase OS=Homo sapiens OX=9606 GN=CNP","CNP",47.578,67.629,36.3,15,19,15,1.035,1.011,1.037,1.012,0.971,0.951,0.952,0.0676,"mitochondria\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0007420 brain development; GO:0048666 neuron development; GO:0009117 nucleotide metabolic process; GO:0006839 mitochondrial transport; GO:0048869 cellular developmental process; GO:0032989 cellular component morphogenesis; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0009607 response to biotic stimulus; GO:0048857 neural nucleus development; GO:0007610 behavior; GO:0021762 substantia nigra development; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:1901292 nucleoside phosphate catabolic process; GO:0007154 cell communication; GO:0048709 oligodendrocyte differentiation; GO:0032990 cell part morphogenesis; GO:0006753 nucleoside phosphate metabolic process; GO:0007005 mitochondrion organization; GO:0048858 cell projection morphogenesis; GO:1901361 organic cyclic compound catabolic process; GO:0060322 head development; GO:0098916 anterograde trans-synaptic signaling; GO:0090559 regulation of membrane permeability; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0030901 midbrain development; GO:0048699 generation of neurons; GO:0002237 response to molecule of bacterial origin; GO:0044281 small molecule metabolic process; GO:0009166 nucleotide catabolic process; GO:0009636 response to toxic substance; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0048812 neuron projection morphogenesis; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0000902 cell morphogenesis; GO:0006810 transport; GO:0019439 aromatic compound catabolic process; GO:1901575 organic substance catabolic process; GO:1902589 single-organism organelle organization; GO:0000226 microtubule cytoskeleton organization; GO:0048513 animal organ development; GO:0042063 gliogenesis; GO:0042221 response to chemical; GO:0007267 cell-cell signaling; GO:0030030 cell projection organization; GO:0044710 single-organism metabolic process; GO:0007417 central nervous system development; GO:0007568 aging; GO:0048856 anatomical structure development; GO:0044708 single-organism behavior; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0008344 adult locomotory behavior; GO:0007006 mitochondrial membrane organization; GO:0006725 cellular aromatic compound metabolic process; GO:0046434 organophosphate catabolic process; GO:1901700 response to oxygen-containing compound; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0048468 cell development; GO:0000904 cell morphogenesis involved in differentiation; GO:0071704 organic substance metabolic process; GO:0009653 anatomical structure morphogenesis; GO:0044270 cellular nitrogen compound catabolic process; GO:0009187 cyclic nucleotide metabolic process; GO:0033993 response to lipid; GO:0030154 cell differentiation; GO:0046483 heterocycle metabolic process; GO:0046902 regulation of mitochondrial membrane permeability; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0006139 nucleobase-containing compound metabolic process; GO:0009214 cyclic nucleotide catabolic process; GO:0007409 axonogenesis; GO:0099537 trans-synaptic signaling; GO:0044248 cellular catabolic process; GO:0030900 forebrain development; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0007275 multicellular organism development; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0030534 adult behavior; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0009617 response to bacterium; GO:0032496 response to lipopolysaccharide; GO:0044712 single-organism catabolic process; GO:0048731 system development; GO:0006807 nitrogen compound metabolic process; GO:0044802 single-organism membrane organization; GO:0010033 response to organic substance; GO:0031175 neuron projection development; GO:0044238 primary metabolic process; GO:0007017 microtubule-based process; GO:0010001 glial cell differentiation; GO:0030182 neuron differentiation; GO:0061564 axon development; GO:0099536 synaptic signaling; GO:0006793 phosphorus metabolic process; GO:0044767 single-organism developmental process; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0019637 organophosphate metabolic process; GO:0007626 locomotory behavior; GO:0007268 chemical synaptic transmission; GO:0051179 localization; GO:0009056 catabolic process; GO:0046700 heterocycle catabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0019867 outer membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005874 microtubule; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0035748 myelin sheath abaxonal region; GO:0044424 intracellular part; GO:0099512 supramolecular fiber; GO:0098858 actin-based cell projection; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0031143 pseudopodium; GO:0044422 organelle part; GO:0048770 pigment granule; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005740 mitochondrial envelope; GO:0005856 cytoskeleton; GO:0035749 myelin sheath adaxonal region; GO:0015630 microtubule cytoskeleton; GO:0043209 myelin sheath; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0019866 organelle inner membrane; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0031968 organelle outer membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0042995 cell projection; GO:0099513 polymeric cytoskeletal fiber; GO:0044429 mitochondrial part; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0005741 mitochondrial outer membrane; GO:0042470 melanosome; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0099081 supramolecular polymer; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031975 envelope; GO:0005902 microvillus; GO:0043230 extracellular organelle; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0003723 RNA binding; GO:0030551 cyclic nucleotide binding; GO:0004112 cyclic-nucleotide phosphodiesterase activity; GO:1901265 nucleoside phosphate binding; GO:0016787 hydrolase activity; GO:0000166 nucleotide binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity; GO:0003824 catalytic activity; GO:0042578 phosphoric ester hydrolase activity; GO:0005488 binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0003676 nucleic acid binding; GO:0008081 phosphoric diester hydrolase activity; GO:0036094 small molecule binding; ","K01121",null,null,"IPR009097; IPR027417; ","RNA ligase/cyclic nucleotide phosphodiesterase; P-loop containing nucleoside triphosphate hydrolase; \r"]
["P09601","Heme oxygenase 1 OS=Homo sapiens OX=9606 GN=HMOX1","HMOX1",32.818,20.125,20.8,4,5,4,0.777,0.802,0.79,1.204,1.124,1.341,1.549,1.14E-3,"peroxisome\r",{"$cut":{"chars":17439,"head":"GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0002694 regulation of leukocyte activation; GO:0035094 response to nicotine; GO:0010941 regulation of cell death; GO:0048732 gland development; GO:0072718 response to cisplatin; GO:0009891 positive regulation of biosynthetic process; GO:0043523 regulation of neuron apoptotic process; GO:0002698 negative regulation of immune effector process; GO:1903306 negative regulation of regulated secretory pathway; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0001525 angiogenesis; GO:0065003 macromolecular complex assembly; GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling; GO:1904018 positive regulation of vasculature development; GO:0055065 metal ion homeostasis; GO:0051051 negative regulation of transport; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:1903531 negative regulation of secretion by cell; GO:0010506 regulation of autophagy; GO:0035296 regulation of tube diameter; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0050776 regulation of immune response; GO:0050673 epithelial cell proliferation; GO:0016241 regulation of macroautophagy; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0010243 response to organonitrogen compound; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:1901698 response to nitrogen compound; GO:0016239 positive regulation of macroautophagy; GO:0060548 negative regulation of cell death; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0072359 circulatory system development; GO:0044707 single-multicellular organism process; GO:0097190 apoptotic signaling pathway; GO:0002718 regulation of cytokine production involved in immune response; GO:0050880 regulation of blood vessel size; GO:0001819 positive regulation of cytokine production; GO:1901700 response to oxygen-containing compound; GO:0017157 regulation of exocytosis; GO:0003018 vascular process in circulatory system; GO:0048519 negative regulation of biological process; GO:0044270 cellular nitrogen compound catabolic process; GO:0009653 anatomical structure morphogenesis; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0043524 negative regulation of neuron apoptotic process; GO:0046483 heterocycle metabolic process; GO:0014900 muscle hyperplasia; GO:2000145 regulation of cell motility; GO:0009889 regulation of biosynthetic process; GO:0009896 positive regulation of catabolic process; GO:0043620 regulation of DNA-templated transcription in response to stress; GO:0070482 response to oxygen levels; GO:0044248 cellular catabolic process; GO:0043300 regulation of leukocyte degranulation; GO:0035150 regulation of tube size; GO:0002246 wound healing involved in inflammatory response; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0048878 chemical homeostasis; GO:0045073 regulation of chemokine biosynthetic process; GO:1901215 negative regulation of neuron death; GO:0071243 cellular response to arsenic-containing substance; GO:0006950 response to stress; GO:0051270 regulation of cellular component movement; GO:0008283 cell proliferation; GO:0002376 immune system process; GO:0034381 plasma lipoprotein particle clearance; GO:0010033 response to organic substance; GO:0007584 response to nutrient; GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress; GO:0006974 cellular response to DNA damage stimulus; GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage; GO:0001889 liver development; GO:0043301 negative regulation of leukocyte degranulation; GO:0007588 excretion; GO:0030336 negative regulation of cell migration; GO:0042542 response to hydrogen peroxide; GO:0031325 positive regulation of cellular metabolic process; GO:0008284 positive regulation of cel"}},"GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0098857 membrane microdomain; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0098590 plasma membrane region; GO:0005622 intracellular; GO:0044425 membrane part; GO:0044464 cell part; GO:0098805 whole membrane; GO:0098589 membrane region; GO:0048471 perinuclear region of cytoplasm; GO:0045121 membrane raft; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0005901 caveola; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0044432 endoplasmic reticulum part; GO:0044853 plasma membrane raft; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0043167 ion binding; GO:0046983 protein dimerization activity; GO:0004630 phospholipase D activity; GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0004392 heme oxygenase (decyclizing) activity; GO:0016298 lipase activity; GO:0004871 signal transducer activity; GO:0016491 oxidoreductase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0020037 heme binding; GO:0042802 identical protein binding; GO:0042578 phosphoric ester hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0042803 protein homodimerization activity; GO:0016788 hydrolase activity, acting on ester bonds; GO:0004620 phospholipase activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0008081 phosphoric diester hydrolase activity; GO:0046906 tetrapyrrole binding; GO:0019899 enzyme binding; ","K00510","HMOX1; heme oxygenase 1 [EC:1.14.14.18]","hsa04978 Mineral absorption - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa04066 HIF-1 signaling pathway - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa04216 Ferroptosis - Homo sapiens (human); hsa00860 Porphyrin and chlorophyll metabolism - Homo sapiens (human); hsa05225 Hepatocellular carcinoma - Homo sapiens (human); hsa05206 MicroRNAs in cancer - Homo sapiens (human); hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human); ","IPR016084; ","\"Haem oxygenase-like, multi-helical; \"\r"]
["P09619","Platelet-derived growth factor receptor beta OS=Homo sapiens OX=9606 GN=PDGFRB","PDGFRB",123.97,22.68,5.7,6,7,6,1.126,1.035,1.118,0.918,0.905,0.972,0.852,0.0101,"plasma membrane\r",{"$cut":{"chars":21393,"head":"GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0048008 platelet-derived growth factor receptor signaling pathway; GO:0022414 reproductive process; GO:0030323 respiratory tube development; GO:0009891 positive regulation of biosynthetic process; GO:0018212 peptidyl-tyrosine modification; GO:0036119 response to platelet-derived growth factor; GO:0072049 comma-shaped body morphogenesis; GO:0044255 cellular lipid metabolic process; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0072275 metanephric glomerulus morphogenesis; GO:0030203 glycosaminoglycan metabolic process; GO:0048145 regulation of fibroblast proliferation; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0001525 angiogenesis; GO:0008152 metabolic process; GO:0048146 positive regulation of fibroblast proliferation; GO:1901137 carbohydrate derivative biosynthetic process; GO:0044093 positive regulation of molecular function; GO:0051493 regulation of cytoskeleton organization; GO:1900238 regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway; GO:0090068 positive regulation of cell cycle process; GO:1900274 regulation of phospholipase C activity; GO:0055013 cardiac muscle cell development; GO:0072203 cell proliferation involved in metanephros development; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0071670 smooth muscle cell chemotaxis; GO:0051054 positive regulation of DNA metabolic process; GO:0080090 regulation of primary metabolic process; GO:0060537 muscle tissue development; GO:0060191 regulation of lipase activity; GO:0044763 single-organism cellular process; GO:0072102 glomerulus morphogenesis; GO:0048870 cell motility; GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway; GO:0072216 positive regulation of metanephros development; GO:0006935 chemotaxis; GO:0035788 cell migration involved in metanephros development; GO:0060976 coronary vasculature development; GO:0001656 metanephros development; GO:0000165 MAPK cascade; GO:0045931 positive regulation of mitotic cell cycle; GO:0035304 regulation of protein dephosphorylation; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0048844 artery morphogenesis; GO:0060548 negative regulation of cell death; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0072111 cell proliferation involved in kidney development; GO:0055001 muscle cell development; GO:0000003 reproduction; GO:0072359 circulatory system development; GO:0016310 phosphorylation; GO:0044707 single-multicellular organism process; GO:0060978 angiogenesis involved in coronary vascular morphogenesis; GO:1901700 response to oxygen-containing compound; GO:0010517 regulation of phospholipase activity; GO:0048519 negative regulation of biological process; GO:0001570 vasculogenesis; GO:0038084 vascular endothelial growth factor signaling pathway; GO:0035265 organ growth; GO:0072075 metanephric mesenchyme development; GO:0009653 anatomical structure morphogenesis; GO:0001654 eye development; GO:0050867 positive regulation of cell activation; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0051345 positive regulation of hydrolase activity; GO:0009889 regulation of biosynthetic process; GO:0060541 respiratory system development; GO:2000145 regulation of cell motility; GO:0070482 response to oxygen levels; GO:0035789 metanephric mesenchymal cell migration; GO:0010959 regulation of metal ion transport; GO:0061061 muscle structure development; GO:0010518 positive regulation of phospholipase activity; GO:0061458 reproductive system development; GO:0048015 phosphatidylinositol-mediated signaling; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0051928 positive regulation of cal"}},"GO:0016020 membrane; GO:0044421 extracellular region part; GO:0016324 apical plasma membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0098590 plasma membrane region; GO:0070013 intracellular organelle lumen; GO:0005925 focal adhesion; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005764 lysosome; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0045177 apical part of cell; GO:0043233 organelle lumen; GO:0005924 cell-substrate adherens junction; GO:0000323 lytic vacuole; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0031226 intrinsic component of plasma membrane; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0016021 integral component of membrane; GO:0043202 lysosomal lumen; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0009986 cell surface; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0005102 receptor binding; GO:0005085 guanyl-nucleotide exchange factor activity; GO:0019838 growth factor binding; GO:0019901 protein kinase binding; GO:0048407 platelet-derived growth factor binding; GO:0004713 protein tyrosine kinase activity; GO:0005515 protein binding; GO:0004672 protein kinase activity; GO:0098772 molecular function regulator; GO:0004888 transmembrane signaling receptor activity; GO:0004871 signal transducer activity; GO:0004714 transmembrane receptor protein tyrosine kinase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0005019 platelet-derived growth factor beta-receptor activity; GO:0005161 platelet-derived growth factor receptor binding; GO:0016301 kinase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0038023 signaling receptor activity; GO:0038085 vascular endothelial growth factor binding; GO:0005524 ATP binding; GO:0004930 G-protein coupled receptor activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0070851 growth factor receptor binding; GO:0000166 nucleotide binding; GO:0019900 kinase binding; GO:0035004 phosphatidylinositol 3-kinase activity; GO:0043548 phosphatidylinositol 3-kinase binding; GO:0019199 transmembrane receptor protein kinase activity; GO:0032549 ribonucleoside binding; GO:0060089 molecular transducer activity; GO:0097367 carbohydrate derivative binding; GO:0004872 receptor activity; GO:0005017 platelet-derived growth factor-activated receptor activity; GO:0052813 phosphatidylinositol bisphosphate kinase activity; GO:0005088 Ras guanyl-nucleotide exchange factor activity; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0004992 platelet activating factor receptor activity; GO:0019899 enzyme binding; GO:0036094 small molecule binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0099600 transmembrane receptor activity; ","K05089","PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]","hsa05231 Choline metabolism in cancer - Homo sapiens (human); hsa04072 Phospholipase D signaling pathway - Homo sapiens (human); hsa04015 Rap1 signaling pathway - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa04014 Ras signaling pathway - Homo sapiens (human); hsa04020 Calcium signaling pathway - Homo sapiens (human); hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human); hsa05230 Central carbon metabolism in cancer - Homo sapiens (human); hsa04010 MAPK signaling pathway - Homo sapiens (human); hsa05166 HTLV-I infection - Homo sapiens (human); hsa05206 MicroRNAs in cancer - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa04540 Gap junction - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa05214 Glioma - Homo sapiens (human); hsa05215 Prostate cancer - Homo sapiens (human); hsa01521 EGFR tyrosine kinase inhibitor resistance - Homo sapiens (human); hsa05218 Melanoma - Homo sapiens (human); hsa04630 Jak-STAT signaling pathway - Homo sapiens (human); ","IPR003598; IPR007110; IPR003599; IPR001245; IPR013098; IPR011009; IPR013783; IPR000719; IPR020635; IPR013151; ","\"Immunoglobulin subtype 2; Immunoglobulin-like domain; Immunoglobulin subtype; Serine-threonine/tyrosine-protein kinase catalytic domain; Immunoglobulin I-set; Protein kinase-like domain; Immunoglobulin-like fold; Protein kinase domain; Tyrosine-protein kinase, catalytic domain; Immunoglobulin; \"\r"]
["P09622","Dihydrolipoyl dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=DLD","DLD",54.177,79.706,31.6,15,28,15,1.082,1.046,1.038,0.945,0.963,0.913,0.891,0.0046,"mitochondria\r","GO:0009116 nucleoside metabolic process; GO:0021700 developmental maturation; GO:0065008 regulation of biological quality; GO:0051068 dihydrolipoamide metabolic process; GO:0019362 pyridine nucleotide metabolic process; GO:0022414 reproductive process; GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate; GO:0044255 cellular lipid metabolic process; GO:0019216 regulation of lipid metabolic process; GO:0044237 cellular metabolic process; GO:0044272 sulfur compound biosynthetic process; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0007286 spermatid development; GO:0044702 single organism reproductive process; GO:0019693 ribose phosphate metabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0009108 coenzyme biosynthetic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009790 embryo development; GO:0046487 glyoxylate metabolic process; GO:0048598 embryonic morphogenesis; GO:0006790 sulfur compound metabolic process; GO:0072350 tricarboxylic acid metabolic process; GO:0009106 lipoate metabolic process; GO:0003006 developmental process involved in reproduction; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:0044281 small molecule metabolic process; GO:0019953 sexual reproduction; GO:0044763 single-organism cellular process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0006081 cellular aldehyde metabolic process; GO:0006732 coenzyme metabolic process; GO:0006084 acetyl-CoA metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0046395 carboxylic acid catabolic process; GO:1901575 organic substance catabolic process; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0022900 electron transport chain; GO:0009063 cellular amino acid catabolic process; GO:0009126 purine nucleoside monophosphate metabolic process; GO:0048609 multicellular organismal reproductive process; GO:0043436 oxoacid metabolic process; GO:0000003 reproduction; GO:0050794 regulation of cellular process; GO:0016310 phosphorylation; GO:0044707 single-multicellular organism process; GO:0046496 nicotinamide nucleotide metabolic process; GO:0009259 ribonucleotide metabolic process; GO:0045454 cell redox homeostasis; GO:0009066 aspartate family amino acid metabolic process; GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate; GO:0009653 anatomical structure morphogenesis; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0050812 regulation of acyl-CoA biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0044248 cellular catabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0007275 multicellular organism development; GO:0009119 ribonucleoside metabolic process; GO:0044711 single-organism biosynthetic process; GO:0007283 spermatogenesis; GO:0006553 lysine metabolic process; GO:0006099 tricarboxylic acid cycle; GO:0035383 thioester metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:1901605 alpha-amino acid metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0006163 purine nucleotide metabolic process; GO:0019217 regulation of fatty acid metabolic process; GO:0009083 branched-chain amino acid catabolic process; GO:0006793 phosphorus metabolic process; GO:0016054 organic acid catabolic process; GO:0048515 spermatid differentiation; GO:0019637 organophosphate metabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0051188 cofactor biosynthetic process; GO:1901606 alpha-amino acid catabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0072524 pyridine-containing compound metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0035384 thioester biosynthetic process; GO:0051196 regulation of coenzyme metabolic process; GO:0006085 acetyl-CoA biosynthetic process; GO:0006520 cellular amino acid metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0048469 cell maturation; GO:0048240 sperm capacitation; GO:0006103 2-oxoglutarate metabolic process; GO:0006629 lipid metabolic process; GO:0051193 regulation of cofactor metabolic process; GO:0032502 developmental process; GO:0031326 regulation of cellular biosynthetic process; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0071616 acyl-CoA biosynthetic process; GO:0055114 oxidation-reduction process; GO:0006119 oxidative phosphorylation; GO:0019725 cellular homeostasis; GO:1901360 organic cyclic compound metabolic process; GO:0006120 mitochondrial electron transport, NADH to ubiquinone; GO:0043603 cellular amide metabolic process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0042391 regulation of membrane potential; GO:0051186 cofactor metabolic process; GO:0010565 regulation of cellular ketone metabolic process; GO:0006101 citrate metabolic process; GO:0009068 aspartate family amino acid catabolic process; GO:0050789 regulation of biological process; GO:0007568 aging; GO:0022412 cellular process involved in reproduction in multicellular organism; GO:0015980 energy derivation by oxidation of organic compounds; GO:0019222 regulation of metabolic process; GO:0006554 lysine catabolic process; GO:1901657 glycosyl compound metabolic process; GO:0042762 regulation of sulfur metabolic process; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:0043648 dicarboxylic acid metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0042773 ATP synthesis coupled electron transport; GO:0022904 respiratory electron transport chain; GO:0048468 cell development; GO:0071704 organic substance metabolic process; GO:0007369 gastrulation; GO:0042592 homeostatic process; GO:0006090 pyruvate metabolic process; GO:0030154 cell differentiation; GO:0007281 germ cell development; GO:0034641 cellular nitrogen compound metabolic process; GO:0006508 proteolysis; GO:0009081 branched-chain amino acid metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0046034 ATP metabolic process; GO:0048232 male gamete generation; GO:0044712 single-organism catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044282 small molecule catabolic process; GO:0006631 fatty acid metabolic process; GO:0045333 cellular respiration; GO:0044249 cellular biosynthetic process; GO:0006637 acyl-CoA metabolic process; GO:0007276 gamete generation; GO:0032504 multicellular organism reproduction; GO:0046128 purine ribonucleoside metabolic process; GO:1901565 organonitrogen compound catabolic process; GO:0044767 single-organism developmental process; GO:0009060 aerobic respiration; GO:0044703 multi-organism reproductive process; GO:0019752 carboxylic acid metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0009056 catabolic process; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:0006086 acetyl-CoA biosynthetic process from pyruvate; GO:0065007 biological regulation; ","GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0043159 acrosomal matrix; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0045240 dihydrolipoyl dehydrogenase complex; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0043209 myelin sheath; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0005929 cilium; GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0042995 cell projection; GO:0044429 mitochondrial part; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:1990234 transferase complex; GO:0045254 pyruvate dehydrogenase complex; GO:0031514 motile cilium; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0001669 acrosomal vesicle; GO:1990204 oxidoreductase complex; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0045252 oxoglutarate dehydrogenase complex; GO:0043234 protein complex; GO:0097223 sperm part; GO:0045239 tricarboxylic acid cycle enzyme complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0004148 dihydrolipoyl dehydrogenase activity; GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:0043544 lipoamide binding; GO:1901265 nucleoside phosphate binding; GO:0050660 flavin adenine dinucleotide binding; GO:0043167 ion binding; GO:0000166 nucleotide binding; GO:0033218 amide binding; GO:0048037 cofactor binding; GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor; GO:1901681 sulfur compound binding; GO:0016491 oxidoreductase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0051287 NAD binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016667 oxidoreductase activity, acting on a sulfur group of donors; GO:0043168 anion binding; GO:0036094 small molecule binding; GO:0050662 coenzyme binding; ","K00382","DLD; dihydrolipoamide dehydrogenase [EC:1.8.1.4]","hsa00280 Valine, leucine and isoleucine degradation - Homo sapiens (human); hsa00640 Propanoate metabolism - Homo sapiens (human); hsa00620 Pyruvate metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00020 Citrate cycle (TCA cycle) - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); hsa00630 Glyoxylate and dicarboxylate metabolism - Homo sapiens (human); hsa00260 Glycine, serine and threonine metabolism - Homo sapiens (human); hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human); ","IPR016156; IPR004099; IPR023753; ","\"FAD/NAD-linked reductase, dimerisation domain; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; FAD/NAD(P)-binding domain; \"\r"]
["P09651","Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1","HNRNPA1",38.746,194.87,33.6,14,34,12,0.872,0.909,0.908,1.105,1.082,1.066,1.21,3.79E-4,"nucleus\r","GO:0044700 single organism signaling; GO:0050658 RNA transport; GO:0065008 regulation of biological quality; GO:0007166 cell surface receptor signaling pathway; GO:0009891 positive regulation of biosynthetic process; GO:0051169 nuclear transport; GO:0046685 response to arsenic-containing substance; GO:0044237 cellular metabolic process; GO:0032204 regulation of telomere maintenance; GO:1903936 cellular response to sodium arsenite; GO:0008152 metabolic process; GO:0015931 nucleobase-containing compound transport; GO:2000279 negative regulation of DNA biosynthetic process; GO:0009719 response to endogenous stimulus; GO:0070848 response to growth factor; GO:0043170 macromolecule metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0044419 interspecies interaction between organisms; GO:0006396 RNA processing; GO:0051716 cellular response to stimulus; GO:0051054 positive regulation of DNA metabolic process; GO:0080090 regulation of primary metabolic process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0031323 regulation of cellular metabolic process; GO:0051704 multi-organism process; GO:1902075 cellular response to salt; GO:0006810 transport; GO:0051053 negative regulation of DNA metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:2001252 positive regulation of chromosome organization; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006913 nucleocytoplasmic transport; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0016071 mRNA metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:1903935 response to sodium arsenite; GO:0051028 mRNA transport; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0032844 regulation of homeostatic process; GO:0032211 negative regulation of telomere maintenance via telomerase; GO:0051236 establishment of RNA localization; GO:1904356 regulation of telomere maintenance via telomere lengthening; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0071774 response to fibroblast growth factor; GO:0051171 regulation of nitrogen compound metabolic process; GO:0008380 RNA splicing; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0071243 cellular response to arsenic-containing substance; GO:0006403 RNA localization; GO:0006405 RNA export from nucleus; GO:0071702 organic substance transport; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:2000278 regulation of DNA biosynthetic process; GO:0033044 regulation of chromosome organization; GO:0009890 negative regulation of biosynthetic process; GO:2001251 negative regulation of chromosome organization; GO:0031325 positive regulation of cellular metabolic process; GO:0032206 positive regulation of telomere maintenance; GO:1902074 response to salt; GO:0051179 localization; GO:0031328 positive regulation of cellular biosynthetic process; GO:0051129 negative regulation of cellular component organization; GO:0044699 single-organism process; GO:0051168 nuclear export; GO:0044764 multi-organism cellular process; GO:0071363 cellular response to growth factor stimulus; GO:0008543 fibroblast growth factor receptor signaling pathway; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0050657 nucleic acid transport; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0032846 positive regulation of homeostatic process; GO:0010035 response to inorganic substance; GO:0033036 macromolecule localization; GO:0070887 cellular response to chemical stimulus; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0031326 regulation of cellular biosynthetic process; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0032212 positive regulation of telomere maintenance via telomerase; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:0010639 negative regulation of organelle organization; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0051052 regulation of DNA metabolic process; GO:0090304 nucleic acid metabolic process; GO:0010638 positive regulation of organelle organization; GO:0019222 regulation of metabolic process; GO:0032210 regulation of telomere maintenance via telomerase; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:1904357 negative regulation of telomere maintenance via telomere lengthening; GO:0016032 viral process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009987 cellular process; GO:1904358 positive regulation of telomere maintenance via telomere lengthening; GO:0033043 regulation of organelle organization; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0032845 negative regulation of homeostatic process; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0032205 negative regulation of telomere maintenance; GO:0051170 nuclear import; GO:0071495 cellular response to endogenous stimulus; GO:0044344 cellular response to fibroblast growth factor stimulus; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0010467 gene expression; GO:0051128 regulation of cellular component organization; GO:0031327 negative regulation of cellular biosynthetic process; GO:2000573 positive regulation of DNA biosynthetic process; GO:0071705 nitrogen compound transport; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005681 spliceosomal complex; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0071013 catalytic step 2 spliceosome; GO:1990904 ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0030529 intracellular ribonucleoprotein complex; GO:0043230 extracellular organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0003677 DNA binding; GO:0003723 RNA binding; GO:1901265 nucleoside phosphate binding; GO:0098847 sequence-specific single stranded DNA binding; GO:0042162 telomeric DNA binding; GO:0003697 single-stranded DNA binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0043565 sequence-specific DNA binding; GO:0043047 single-stranded telomeric DNA binding; GO:0003727 single-stranded RNA binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0061752 telomeric repeat-containing RNA binding; GO:0005488 binding; GO:0098505 G-rich strand telomeric DNA binding; GO:0003676 nucleic acid binding; GO:0036094 small molecule binding; ","K12741","HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3","hsa03040 Spliceosome - Homo sapiens (human); ","IPR000504; IPR012677; ","RNA recognition motif domain; Nucleotide-binding alpha-beta plait domain; \r"]
["P09668","Pro-cathepsin H OS=Homo sapiens OX=9606 GN=CTSH","CTSH",37.393,11.153,8.7,2,4,2,1.085,0.958,0.862,0.977,0.982,0.997,1.018,0.775,"extracellular\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0010941 regulation of cell death; GO:0030335 positive regulation of cell migration; GO:0045321 leukocyte activation; GO:0032270 positive regulation of cellular protein metabolic process; GO:0010813 neuropeptide catabolic process; GO:0006518 peptide metabolic process; GO:0030323 respiratory tube development; GO:0044237 cellular metabolic process; GO:0048754 branching morphogenesis of an epithelial tube; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:1904018 positive regulation of vasculature development; GO:0009719 response to endogenous stimulus; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0001906 cell killing; GO:0031638 zymogen activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0052548 regulation of endopeptidase activity; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0010632 regulation of epithelial cell migration; GO:0010950 positive regulation of endopeptidase activity; GO:0080090 regulation of primary metabolic process; GO:0002456 T cell mediated immunity; GO:0001763 morphogenesis of a branching structure; GO:0035239 tube morphogenesis; GO:0044763 single-organism cellular process; GO:0051272 positive regulation of cellular component movement; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0050776 regulation of immune response; GO:0001656 metanephros development; GO:0006810 transport; GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0000165 MAPK cascade; GO:1901575 organic substance catabolic process; GO:0048513 animal organ development; GO:0001909 leukocyte mediated cytotoxicity; GO:0051336 regulation of hydrolase activity; GO:0032526 response to retinoic acid; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0030163 protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0009887 animal organ morphogenesis; GO:0002682 regulation of immune system process; GO:0045765 regulation of angiogenesis; GO:0006464 cellular protein modification process; GO:0060548 negative regulation of cell death; GO:0051094 positive regulation of developmental process; GO:0010952 positive regulation of peptidase activity; GO:0043068 positive regulation of programmed cell death; GO:0050794 regulation of cellular process; GO:0002009 morphogenesis of an epithelium; GO:0044707 single-multicellular organism process; GO:0016310 phosphorylation; GO:0002283 neutrophil activation involved in immune response; GO:0042127 regulation of cell proliferation; GO:2001056 positive regulation of cysteine-type endopeptidase activity; GO:1901700 response to oxygen-containing compound; GO:0043067 regulation of programmed cell death; GO:0044267 cellular protein metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:2000147 positive regulation of cell motility; GO:0060249 anatomical structure homeostasis; GO:0051239 regulation of multicellular organismal process; GO:0009653 anatomical structure morphogenesis; GO:0001913 T cell mediated cytotoxicity; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0060448 dichotomous subdivision of terminal units involved in lung branching; GO:0051345 positive regulation of hydrolase activity; GO:0010628 positive regulation of gene expression; GO:0060541 respiratory system development; GO:2000145 regulation of cell motility; GO:0044248 cellular catabolic process; GO:0007275 multicellular organism development; GO:0002449 lymphocyte mediated immunity; GO:0009966 regulation of signal transduction; GO:0048878 chemical homeostasis; GO:0097067 cellular response to thyroid hormone stimulus; GO:0023014 signal transduction by protein phosphorylation; GO:0001822 kidney development; GO:0060562 epithelial tube morphogenesis; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0030334 regulation of cell migration; GO:0010033 response to organic substance; GO:0030162 regulation of proteolysis; GO:0060600 dichotomous subdivision of an epithelial terminal unit; GO:0044238 primary metabolic process; GO:0002263 cell activation involved in immune response; GO:0045055 regulated exocytosis; GO:0051247 positive regulation of protein metabolic process; GO:0061138 morphogenesis of a branching epithelium; GO:0006793 phosphorus metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0001775 cell activation; GO:0031647 regulation of protein stability; GO:0012501 programmed cell death; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:0006955 immune response; GO:0043412 macromolecule modification; GO:0050793 regulation of developmental process; GO:0008284 positive regulation of cell proliferation; GO:0006887 exocytosis; GO:1901564 organonitrogen compound metabolic process; GO:0001101 response to acid chemical; GO:0040017 positive regulation of locomotion; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0016485 protein processing; GO:0033619 membrane protein proteolysis; GO:0048871 multicellular organismal homeostasis; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:2001233 regulation of apoptotic signaling pathway; GO:0007165 signal transduction; GO:0048729 tissue morphogenesis; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0043171 peptide catabolic process; GO:0002250 adaptive immune response; GO:0006915 apoptotic process; GO:0097066 response to thyroid hormone; GO:0070887 cellular response to chemical stimulus; GO:0002274 myeloid leukocyte activation; GO:0030324 lung development; GO:0032502 developmental process; GO:0035295 tube development; GO:0060429 epithelium development; GO:0010468 regulation of gene expression; GO:0009888 tissue development; GO:2000116 regulation of cysteine-type endopeptidase activity; GO:0002446 neutrophil mediated immunity; GO:0048522 positive regulation of cellular process; GO:0043603 cellular amide metabolic process; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0002444 myeloid leukocyte mediated immunity; GO:0010942 positive regulation of cell death; GO:0001655 urogenital system development; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0032940 secretion by cell; GO:0032870 cellular response to hormone stimulus; GO:0001894 tissue homeostasis; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0043299 leukocyte degranulation; GO:0052547 regulation of peptidase activity; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0060425 lung morphogenesis; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0043069 negative regulation of programmed cell death; GO:0048875 chemical homeostasis within a tissue; GO:0002252 immune effector process; GO:0070371 ERK1 and ERK2 cascade; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0043065 positive regulation of apoptotic process; GO:0072001 renal system development; GO:0050896 response to stimulus; GO:0045766 positive regulation of angiogenesis; GO:0071704 organic substance metabolic process; GO:0033993 response to lipid; GO:0042592 homeostatic process; GO:0045862 positive regulation of proteolysis; GO:0006468 protein phosphorylation; GO:0043066 negative regulation of apoptotic process; GO:0023056 positive regulation of signaling; GO:2001235 positive regulation of apoptotic signaling pathway; GO:0034641 cellular nitrogen compound metabolic process; GO:0006508 proteolysis; GO:0036230 granulocyte activation; GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:0043129 surfactant homeostasis; GO:0044265 cellular macromolecule catabolic process; GO:0035556 intracellular signal transduction; GO:1901342 regulation of vasculature development; GO:0006807 nitrogen compound metabolic process; GO:0010634 positive regulation of epithelial cell migration; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0031648 protein destabilization; GO:0043085 positive regulation of catalytic activity; GO:0010815 bradykinin catabolic process; GO:0002366 leukocyte activation involved in immune response; GO:0019882 antigen processing and presentation; GO:0060441 epithelial tube branching involved in lung morphogenesis; GO:0042119 neutrophil activation; GO:1901565 organonitrogen compound catabolic process; GO:0008219 cell death; GO:0071495 cellular response to endogenous stimulus; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0009967 positive regulation of signal transduction; GO:0051604 protein maturation; GO:0009725 response to hormone; GO:0040012 regulation of locomotion; GO:0009056 catabolic process; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:1904724 tertiary granule lumen; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0000932 P-body; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0042599 lamellar body; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0031906 late endosome lumen; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0097486 multivesicular body lumen; GO:0005768 endosome; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0005771 multivesicular body; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0005770 late endosome; GO:0043232 intracellular non-membrane-bounded organelle; GO:0070820 tertiary granule; GO:0044446 intracellular organelle part; GO:0044440 endosomal part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0031904 endosome lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0035770 ribonucleoprotein granule; GO:0005773 vacuole; GO:0097208 alveolar lamellar body; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0008233 peptidase activity; GO:0042562 hormone binding; GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process; GO:0008236 serine-type peptidase activity; GO:0061134 peptidase regulator activity; GO:0016504 peptidase activator activity; GO:0016787 hydrolase activity; GO:0008234 cysteine-type peptidase activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0004888 transmembrane signaling receptor activity; GO:0004871 signal transducer activity; GO:0030108 HLA-A specific activating MHC class I receptor activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0004197 cysteine-type endopeptidase activity; GO:0016505 peptidase activator activity involved in apoptotic process; GO:0008047 enzyme activator activity; GO:0038023 signaling receptor activity; GO:0008238 exopeptidase activity; GO:0032397 activating MHC class I receptor activity; GO:0032393 MHC class I receptor activity; GO:0004177 aminopeptidase activity; GO:0004175 endopeptidase activity; GO:0004252 serine-type endopeptidase activity; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process; GO:0030234 enzyme regulator activity; GO:0017171 serine hydrolase activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0070324 thyroid hormone binding; GO:0099600 transmembrane receptor activity; ","K01366","CTSH; cathepsin H [EC:3.4.22.16]","hsa04142 Lysosome - Homo sapiens (human); hsa04210 Apoptosis - Homo sapiens (human); ","IPR013201; IPR000668; ","\"Cathepsin propeptide inhibitor domain (I29); Peptidase C1A, papain C-terminal; \"\r"]
["P09669","Cytochrome c oxidase subunit 6C OS=Homo sapiens OX=9606 GN=COX6C","COX6C",8.7813,2.0828,12,1,2,1,0.989,0.934,0.94,0.969,1.108,1.059,1.095,0.107,"mitochondria\r","GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0006123 mitochondrial electron transport, cytochrome c to oxygen; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0006753 nucleoside phosphate metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0044765 single-organism transport; GO:0098655 cation transmembrane transport; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0006119 oxidative phosphorylation; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0006810 transport; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0022900 electron transport chain; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0098662 inorganic cation transmembrane transport; GO:0016310 phosphorylation; GO:0034220 ion transmembrane transport; GO:0006725 cellular aromatic compound metabolic process; GO:0042773 ATP synthesis coupled electron transport; GO:0009259 ribonucleotide metabolic process; GO:0022904 respiratory electron transport chain; GO:0071704 organic substance metabolic process; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0006812 cation transport; GO:0006139 nucleobase-containing compound metabolic process; GO:1902600 hydrogen ion transmembrane transport; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009119 ribonucleoside metabolic process; GO:0009987 cellular process; GO:0046034 ATP metabolic process; GO:0098660 inorganic ion transmembrane transport; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0045333 cellular respiration; GO:0006818 hydrogen transport; GO:0015992 proton transport; GO:0006163 purine nucleotide metabolic process; GO:0055085 transmembrane transport; GO:0046128 purine ribonucleoside metabolic process; GO:0006793 phosphorus metabolic process; GO:0006811 ion transport; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0051179 localization; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:0015672 monovalent inorganic cation transport; GO:1901564 organonitrogen compound metabolic process; GO:0009123 nucleoside monophosphate metabolic process; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044429 mitochondrial part; GO:0031090 organelle membrane; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005740 mitochondrial envelope; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0031975 envelope; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0015075 ion transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0015077 monovalent inorganic cation transmembrane transporter activity; GO:0016676 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor; GO:0016675 oxidoreductase activity, acting on a heme group of donors; GO:0015078 hydrogen ion transmembrane transporter activity; GO:0015002 heme-copper terminal oxidase activity; GO:0016491 oxidoreductase activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0009055 electron carrier activity; GO:0004129 cytochrome-c oxidase activity; GO:0003824 catalytic activity; GO:0022890 inorganic cation transmembrane transporter activity; GO:0008324 cation transmembrane transporter activity; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; ","K02268","COX6C; cytochrome c oxidase subunit 6c","hsa04260 Cardiac muscle contraction - Homo sapiens (human); hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); "]
["P09758","Tumor-associated calcium signal transducer 2 OS=Homo sapiens OX=9606 GN=TACSTD2","TACSTD2",35.709,50.457,36.8,10,15,10,0.811,1.059,1.016,1.015,1.152,0.998,1.097,0.363,"plasma membrane\r","GO:0072028 nephron morphogenesis; GO:0044700 single organism signaling; GO:0061333 renal tubule morphogenesis; GO:0060491 regulation of cell projection assembly; GO:0072080 nephron tubule development; GO:0007166 cell surface receptor signaling pathway; GO:0007601 visual perception; GO:0050877 neurological system process; GO:0022610 biological adhesion; GO:0050678 regulation of epithelial cell proliferation; GO:0032879 regulation of localization; GO:0007155 cell adhesion; GO:0051493 regulation of cytoskeleton organization; GO:0051716 cellular response to stimulus; GO:0010632 regulation of epithelial cell migration; GO:0035239 tube morphogenesis; GO:2000146 negative regulation of cell motility; GO:0032501 multicellular organismal process; GO:0048513 animal organ development; GO:0009887 animal organ morphogenesis; GO:0010721 negative regulation of cell development; GO:0051094 positive regulation of developmental process; GO:1902903 regulation of supramolecular fiber organization; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0002009 morphogenesis of an epithelium; GO:0007162 negative regulation of cell adhesion; GO:0042127 regulation of cell proliferation; GO:0032956 regulation of actin cytoskeleton organization; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0045597 positive regulation of cell differentiation; GO:0051239 regulation of multicellular organismal process; GO:0060688 regulation of morphogenesis of a branching structure; GO:0090189 regulation of branching involved in ureteric bud morphogenesis; GO:2000738 positive regulation of stem cell differentiation; GO:0009653 anatomical structure morphogenesis; GO:2000145 regulation of cell motility; GO:1900024 regulation of substrate adhesion-dependent cell spreading; GO:0031345 negative regulation of cell projection organization; GO:0007275 multicellular organism development; GO:0072009 nephron epithelium development; GO:0010771 negative regulation of cell morphogenesis involved in differentiation; GO:0060562 epithelial tube morphogenesis; GO:0001822 kidney development; GO:0051270 regulation of cellular component movement; GO:0032231 regulation of actin filament bundle assembly; GO:0048731 system development; GO:0060284 regulation of cell development; GO:1900027 regulation of ruffle assembly; GO:2000736 regulation of stem cell differentiation; GO:0008283 cell proliferation; GO:0032970 regulation of actin filament-based process; GO:0030334 regulation of cell migration; GO:0061326 renal tubule development; GO:0030155 regulation of cell adhesion; GO:0051492 regulation of stress fiber assembly; GO:0030336 negative regulation of cell migration; GO:0090183 regulation of kidney development; GO:0072073 kidney epithelium development; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:0010810 regulation of cell-substrate adhesion; GO:0090185 negative regulation of kidney development; GO:0050793 regulation of developmental process; GO:0001657 ureteric bud development; GO:1905331 negative regulation of morphogenesis of an epithelium; GO:0051093 negative regulation of developmental process; GO:0010633 negative regulation of epithelial cell migration; GO:0051129 negative regulation of cellular component organization; GO:0044699 single-organism process; GO:0051241 negative regulation of multicellular organismal process; GO:0060675 ureteric bud morphogenesis; GO:0001823 mesonephros development; GO:0040013 negative regulation of locomotion; GO:1905330 regulation of morphogenesis of an epithelium; GO:0007165 signal transduction; GO:0048729 tissue morphogenesis; GO:1900025 negative regulation of substrate adhesion-dependent cell spreading; GO:0007154 cell communication; GO:0045596 negative regulation of cell differentiation; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0035295 tube development; GO:0007600 sensory perception; GO:0009888 tissue development; GO:0051494 negative regulation of cytoskeleton organization; GO:0098609 cell-cell adhesion; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0072171 mesonephric tubule morphogenesis; GO:0010639 negative regulation of organelle organization; GO:0001655 urogenital system development; GO:0050789 regulation of biological process; GO:1902904 negative regulation of supramolecular fiber organization; GO:0072163 mesonephric epithelium development; GO:0010812 negative regulation of cell-substrate adhesion; GO:0048856 anatomical structure development; GO:0032232 negative regulation of actin filament bundle assembly; GO:0061217 regulation of mesonephros development; GO:0051271 negative regulation of cellular component movement; GO:2000026 regulation of multicellular organismal development; GO:0072078 nephron tubule morphogenesis; GO:0061218 negative regulation of mesonephros development; GO:0072001 renal system development; GO:0044087 regulation of cellular component biogenesis; GO:0031344 regulation of cell projection organization; GO:0050896 response to stimulus; GO:0072088 nephron epithelium morphogenesis; GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis; GO:2000027 regulation of organ morphogenesis; GO:0072006 nephron development; GO:0060993 kidney morphogenesis; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0003008 system process; GO:0072164 mesonephric tubule development; GO:0033043 regulation of organelle organization; GO:0051497 negative regulation of stress fiber assembly; GO:0050953 sensory perception of light stimulus; GO:0048518 positive regulation of biological process; GO:1900028 negative regulation of ruffle assembly; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0051128 regulation of cellular component organization; GO:0040012 regulation of locomotion; GO:0022604 regulation of cell morphogenesis; GO:0065007 biological regulation; ","GO:0016323 basolateral plasma membrane; GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0070062 extracellular exosome; GO:0098590 plasma membrane region; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0031226 intrinsic component of plasma membrane; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0016328 lateral plasma membrane; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0009925 basal plasma membrane; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0045178 basal part of cell; ","GO:0060089 molecular transducer activity; GO:0005515 protein binding; GO:0004872 receptor activity; GO:0005488 binding; ","K17288",null,null,"IPR000716; ","Thyroglobulin type-1; \r"]
["P09871","Complement C1s subcomponent OS=Homo sapiens OX=9606 GN=C1S","C1S",76.684,89.467,26.6,15,24,14,1.019,1.033,1.027,1,0.975,0.998,0.966,0.0178,"extracellular\r","GO:0016064 immunoglobulin mediated immune response; GO:0002252 immune effector process; GO:0006959 humoral immune response; GO:0050896 response to stimulus; GO:0045087 innate immune response; GO:0019724 B cell mediated immunity; GO:0071704 organic substance metabolic process; GO:0006956 complement activation; GO:0008152 metabolic process; GO:0001867 complement activation, lectin pathway; GO:0002250 adaptive immune response; GO:0006958 complement activation, classical pathway; GO:0006508 proteolysis; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0002449 lymphocyte mediated immunity; GO:0050778 positive regulation of immune response; GO:0002253 activation of immune response; GO:0002443 leukocyte mediated immunity; GO:0006950 response to stress; GO:0072376 protein activation cascade; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0050776 regulation of immune response; GO:0050789 regulation of biological process; GO:0002684 positive regulation of immune system process; GO:0048583 regulation of response to stimulus; GO:0002682 regulation of immune system process; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0006952 defense response; GO:0006955 immune response; GO:0048584 positive regulation of response to stimulus; GO:0065007 biological regulation; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0072562 blood microparticle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:0004252 serine-type endopeptidase activity; GO:0004175 endopeptidase activity; GO:0008233 peptidase activity; GO:0042802 identical protein binding; GO:0017171 serine hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0008236 serine-type peptidase activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0005509 calcium ion binding; ","K01331","C1S; complement component 1, s subcomponent [EC:3.4.21.42]","hsa05322 Systemic lupus erythematosus - Homo sapiens (human); hsa05133 Pertussis - Homo sapiens (human); hsa04610 Complement and coagulation cascades - Homo sapiens (human); hsa05150 Staphylococcus aureus infection - Homo sapiens (human); ","IPR009003; IPR000859; IPR000436; IPR001254; IPR001881; ","\"Peptidase S1, PA clan; CUB domain; Sushi/SCR/CCP domain; Serine proteases, trypsin domain; EGF-like calcium-binding domain; \"\r"]
["P09874","Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1","PARP1",113.08,31.827,12.4,12,13,12,1.048,1.03,1.019,1.006,0.98,0.985,0.959,0.0222,"nucleus\r",{"$cut":{"chars":19531,"head":"GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0006266 DNA ligation; GO:0045980 negative regulation of nucleotide metabolic process; GO:0006289 nucleotide-excision repair; GO:1904645 response to beta-amyloid; GO:0043523 regulation of neuron apoptotic process; GO:0009891 positive regulation of biosynthetic process; GO:0014742 positive regulation of muscle hypertrophy; GO:0044237 cellular metabolic process; GO:1904181 positive regulation of membrane depolarization; GO:0045978 negative regulation of nucleoside metabolic process; GO:0008152 metabolic process; GO:0014743 regulation of muscle hypertrophy; GO:1901137 carbohydrate derivative biosynthetic process; GO:0065003 macromolecular complex assembly; GO:0044093 positive regulation of molecular function; GO:0044057 regulation of system process; GO:0019693 ribose phosphate metabolic process; GO:0051099 positive regulation of binding; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0002520 immune system development; GO:0071559 response to transforming growth factor beta; GO:0022616 DNA strand elongation; GO:0006471 protein ADP-ribosylation; GO:0010243 response to organonitrogen compound; GO:0080135 regulation of cellular response to stress; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0051223 regulation of protein transport; GO:0030809 negative regulation of nucleotide biosynthetic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0043504 mitochondrial DNA repair; GO:0090305 nucleic acid phosphodiester bond hydrolysis; GO:0042307 positive regulation of protein import into nucleus; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0044707 single-multicellular organism process; GO:0009259 ribonucleotide metabolic process; GO:0006259 DNA metabolic process; GO:0051901 positive regulation of mitochondrial depolarization; GO:1901700 response to oxygen-containing compound; GO:0003254 regulation of membrane depolarization; GO:0048519 negative regulation of biological process; GO:0044030 regulation of DNA methylation; GO:0045892 negative regulation of transcription, DNA-templated; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0060390 regulation of SMAD protein import into nucleus; GO:0009889 regulation of biosynthetic process; GO:1904760 regulation of myofibroblast differentiation; GO:1902680 positive regulation of RNA biosynthetic process; GO:0006950 response to stress; GO:0023019 signal transduction involved in regulation of gene expression; GO:0007179 transforming growth factor beta receptor signaling pathway; GO:0002376 immune system process; GO:0009141 nucleoside triphosphate metabolic process; GO:0010033 response to organic substance; GO:1901576 organic substance biosynthetic process; GO:0006163 purine nucleotide metabolic process; GO:0006974 cellular response to DNA damage stimulus; GO:0010611 regulation of cardiac muscle hypertrophy; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:1900182 positive regulation of protein localization to nucleus; GO:0043502 regulation of muscle adaptation; GO:0000725 recombinational repair; GO:0009890 negative regulation of biosynthetic process; GO:2001251 negative regulation of chromosome organization; GO:1904646 cellular response to beta-amyloid; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0006294 nucleotide-excision repair, preincision complex assembly; GO:0019637 organophosphate metabolic process; GO:0043412 macromolecule modification; GO:1903827 regulation of cellular protein localization; GO:0045936 negative regulation of phosphate metabolic process; GO:004"}},"GO:0016020 membrane; GO:0000784 nuclear chromosome, telomeric region; GO:0000781 chromosome, telomeric region; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044454 nuclear chromosome part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005694 chromosome; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005635 nuclear envelope; GO:0043232 intracellular non-membrane-bounded organelle; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005667 transcription factor complex; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0098687 chromosomal region; GO:0005634 nucleus; GO:0031975 envelope; GO:0000228 nuclear chromosome; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0047485 protein N-terminus binding; GO:0003910 DNA ligase (ATP) activity; GO:0005102 receptor binding; GO:0019901 protein kinase binding; GO:0016874 ligase activity; GO:0005515 protein binding; GO:0051427 hormone receptor binding; GO:0003909 DNA ligase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0042826 histone deacetylase binding; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0035258 steroid hormone receptor binding; GO:0043169 cation binding; GO:0016740 transferase activity; GO:0003677 DNA binding; GO:0003723 RNA binding; GO:0030331 estrogen receptor binding; GO:0016763 transferase activity, transferring pentosyl groups; GO:0003950 NAD+ ADP-ribosyltransferase activity; GO:0043167 ion binding; GO:0016886 ligase activity, forming phosphoric ester bonds; GO:0000166 nucleotide binding; GO:0008270 zinc ion binding; GO:0070412 R-SMAD binding; GO:0019900 kinase binding; GO:0048037 cofactor binding; GO:0046914 transition metal ion binding; GO:0051287 NAD binding; GO:0003676 nucleic acid binding; GO:0035257 nuclear hormone receptor binding; GO:0046872 metal ion binding; GO:0016757 transferase activity, transferring glycosyl groups; GO:0046332 SMAD binding; GO:0019899 enzyme binding; GO:0008134 transcription factor binding; GO:0036094 small molecule binding; GO:0050662 coenzyme binding; ","K10798","PARP; poly [ADP-ribose] polymerase [EC:2.4.2.30]","hsa04210 Apoptosis - Homo sapiens (human); hsa04217 Necroptosis - Homo sapiens (human); hsa03410 Base excision repair - Homo sapiens (human); hsa04064 NF-kappa B signaling pathway - Homo sapiens (human); ","IPR008893; IPR004102; IPR012982; IPR001510; IPR012317; IPR001357; ","\"WGR domain; Poly(ADP-ribose) polymerase, regulatory domain; PADR1 domain; Zinc finger, PARP-type; Poly(ADP-ribose) polymerase, catalytic domain; BRCT domain; \"\r"]
["P09914","Interferon-induced protein with tetratricopeptide repeats 1 OS=Homo sapiens OX=9606 GN=IFIT1","IFIT1",55.36,48.561,8.6,3,5,3,0.956,0.99,0.904,1.089,1.01,1.056,1.107,0.0412,"cytoplasm\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0007166 cell surface receptor signaling pathway; GO:0098542 defense response to other organism; GO:0002698 negative regulation of immune effector process; GO:0044699 single-organism process; GO:1902581 multi-organism cellular localization; GO:0044764 multi-organism cellular process; GO:0032091 negative regulation of protein binding; GO:0031347 regulation of defense response; GO:0071345 cellular response to cytokine stimulus; GO:0015031 protein transport; GO:0009607 response to biotic stimulus; GO:0051234 establishment of localization; GO:0019060 intracellular transport of viral protein in host cell; GO:0009605 response to external stimulus; GO:1902583 multi-organism intracellular transport; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0032102 negative regulation of response to external stimulus; GO:0051095 regulation of helicase activity; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0044419 interspecies interaction between organisms; GO:0075733 intracellular transport of virus; GO:0002697 regulation of immune effector process; GO:0050691 regulation of defense response to virus by host; GO:0030581 symbiont intracellular protein transport in host; GO:0070887 cellular response to chemical stimulus; GO:0048525 negative regulation of viral process; GO:1903902 positive regulation of viral life cycle; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0043902 positive regulation of multi-organism process; GO:0002832 negative regulation of response to biotic stimulus; GO:0034097 response to cytokine; GO:0050687 negative regulation of defense response to virus; GO:0051098 regulation of binding; GO:0048522 positive regulation of cellular process; GO:0043331 response to dsRNA; GO:0034340 response to type I interferon; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0045069 regulation of viral genome replication; GO:0043086 negative regulation of catalytic activity; GO:0023052 signaling; GO:0051704 multi-organism process; GO:0002683 negative regulation of immune system process; GO:0050689 negative regulation of defense response to virus by host; GO:0006810 transport; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0051607 defense response to virus; GO:0051336 regulation of hydrolase activity; GO:1901699 cellular response to nitrogen compound; GO:0051100 negative regulation of binding; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0065009 regulation of molecular function; GO:0002682 regulation of immune system process; GO:0044092 negative regulation of molecular function; GO:0006952 defense response; GO:0009615 response to virus; GO:0050794 regulation of cellular process; GO:0060337 type I interferon signaling pathway; GO:1902579 multi-organism localization; GO:0046907 intracellular transport; GO:0002831 regulation of response to biotic stimulus; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0002252 immune effector process; GO:0071310 cellular response to organic substance; GO:0019058 viral life cycle; GO:0043207 response to external biotic stimulus; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0051346 negative regulation of hydrolase activity; GO:0045087 innate immune response; GO:1903901 negative regulation of viral life cycle; GO:0043393 regulation of protein binding; GO:0042592 homeostatic process; GO:0050688 regulation of defense response to virus; GO:0051097 negative regulation of helicase activity; GO:0016032 viral process; GO:0006886 intracellular protein transport; GO:0071357 cellular response to type I interferon; GO:0034613 cellular protein localization; GO:0045070 positive regulation of viral genome replication; GO:0019221 cytokine-mediated signaling pathway; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0031348 negative regulation of defense response; GO:0071359 cellular response to dsRNA; GO:0046794 transport of virus; GO:0006950 response to stress; GO:0043330 response to exogenous dsRNA; GO:0043900 regulation of multi-organism process; GO:0050792 regulation of viral process; GO:0071407 cellular response to organic cyclic compound; GO:0032101 regulation of response to external stimulus; GO:0071702 organic substance transport; GO:0002376 immune system process; GO:0048585 negative regulation of response to stimulus; GO:0010033 response to organic substance; GO:0045071 negative regulation of viral genome replication; GO:0051701 interaction with host; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0043901 negative regulation of multi-organism process; GO:0044766 multi-organism transport; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0048524 positive regulation of viral process; GO:0071360 cellular response to exogenous dsRNA; GO:0051708 intracellular protein transport in other organism involved in symbiotic interaction; GO:0046719 regulation by virus of viral protein levels in host cell; GO:0051179 localization; GO:0006955 immune response; GO:1903900 regulation of viral life cycle; GO:0065007 biological regulation; ","GO:0043657 host cell; GO:0044217 other organism part; GO:0044216 other organism cell; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044215 other organism; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0018995 host; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005515 protein binding; GO:0005488 binding; GO:0003676 nucleic acid binding; ","K14217","IFIT1; interferon-induced protein with tetratricopeptide repeats 1","hsa05168 Herpes simplex infection - Homo sapiens (human); hsa05160 Hepatitis C - Homo sapiens (human); ","IPR011990; IPR013026; ","Tetratricopeptide-like helical domain; Tetratricopeptide repeat-containing domain; \r"]
["P09917","Arachidonate 5-lipoxygenase OS=Homo sapiens OX=9606 GN=ALOX5","ALOX5",77.982,11.803,3.4,2,3,2,0.965,1.053,0.975,1.034,0.916,1.067,1.008,0.909,"cytoplasm\r","GO:0045321 leukocyte activation; GO:0016053 organic acid biosynthetic process; GO:0019370 leukotriene biosynthetic process; GO:0002540 leukotriene production involved in inflammatory response; GO:2001300 lipoxin metabolic process; GO:1901568 fatty acid derivative metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:0008610 lipid biosynthetic process; GO:0046456 icosanoid biosynthetic process; GO:0008152 metabolic process; GO:0002532 production of molecular mediator involved in inflammatory response; GO:0032787 monocarboxylic acid metabolic process; GO:0019372 lipoxygenase pathway; GO:0006690 icosanoid metabolic process; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0006629 lipid metabolic process; GO:0002443 leukocyte mediated immunity; GO:0055114 oxidation-reduction process; GO:0002446 neutrophil mediated immunity; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006636 unsaturated fatty acid biosynthetic process; GO:0032501 multicellular organismal process; GO:0006633 fatty acid biosynthetic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0006810 transport; GO:0046394 carboxylic acid biosynthetic process; GO:0032940 secretion by cell; GO:0044710 single-organism metabolic process; GO:0006954 inflammatory response; GO:0043299 leukocyte degranulation; GO:0006952 defense response; GO:0006082 organic acid metabolic process; GO:0043436 oxoacid metabolic process; GO:0033559 unsaturated fatty acid metabolic process; GO:0044707 single-multicellular organism process; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0050896 response to stimulus; GO:0002538 arachidonic acid metabolite production involved in inflammatory response; GO:0071704 organic substance metabolic process; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0044711 single-organism biosynthetic process; GO:0006950 response to stress; GO:0016192 vesicle-mediated transport; GO:0006691 leukotriene metabolic process; GO:1901570 fatty acid derivative biosynthetic process; GO:0002376 immune system process; GO:0006631 fatty acid metabolic process; GO:0044238 primary metabolic process; GO:0043312 neutrophil degranulation; GO:1901576 organic substance biosynthetic process; GO:0002263 cell activation involved in immune response; GO:0044249 cellular biosynthetic process; GO:0002366 leukocyte activation involved in immune response; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:0044283 small molecule biosynthetic process; GO:0019752 carboxylic acid metabolic process; GO:0001775 cell activation; GO:0051179 localization; GO:0006955 immune response; GO:0072330 monocarboxylic acid biosynthetic process; GO:0006887 exocytosis; ","GO:0016020 membrane; GO:0034774 secretory granule lumen; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0005641 nuclear envelope lumen; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0031965 nuclear membrane; GO:0031983 vesicle lumen; GO:0031970 organelle envelope lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0005635 nuclear envelope; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0016363 nuclear matrix; GO:0031975 envelope; GO:0034399 nuclear periphery; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen; GO:0005506 iron ion binding; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0051213 dioxygenase activity; GO:0005488 binding; GO:0043167 ion binding; GO:0004051 arachidonate 5-lipoxygenase activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0016491 oxidoreductase activity; ","K00461","ALOX5; arachidonate 5-lipoxygenase [EC:1.13.11.34]","hsa04664 Fc epsilon RI signaling pathway - Homo sapiens (human); hsa04913 Ovarian steroidogenesis - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa04726 Serotonergic synapse - Homo sapiens (human); hsa00590 Arachidonic acid metabolism - Homo sapiens (human); hsa05145 Toxoplasmosis - Homo sapiens (human); ","IPR001024; IPR013819; ","\"PLAT/LH2 domain; Lipoxygenase, C-terminal; \"\r"]
["P09936","Ubiquitin carboxyl-terminal hydrolase isozyme L1 OS=Homo sapiens OX=9606 GN=UCHL1","UCHL1",24.824,73.158,39.5,7,11,7,1.223,1.182,1.092,0.873,0.85,0.832,0.731,0.000999,"cytoplasm\r","GO:0032989 cellular component morphogenesis; GO:0044237 cellular metabolic process; GO:0050877 neurological system process; GO:0007610 behavior; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0008152 metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0044765 single-organism transport; GO:0007399 nervous system development; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0048699 generation of neurons; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0048812 neuron projection morphogenesis; GO:0031323 regulation of cellular metabolic process; GO:0043086 negative regulation of catalytic activity; GO:0010506 regulation of autophagy; GO:0032501 multicellular organismal process; GO:0016241 regulation of macroautophagy; GO:0006810 transport; GO:0000902 cell morphogenesis; GO:1901575 organic substance catabolic process; GO:0034643 establishment of mitochondrion localization, microtubule-mediated; GO:0055002 striated muscle cell development; GO:1902532 negative regulation of intracellular signal transduction; GO:0030163 protein catabolic process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0044708 single-organism behavior; GO:0051640 organelle localization; GO:0055001 muscle cell development; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0044707 single-multicellular organism process; GO:0007412 axon target recognition; GO:0043407 negative regulation of MAP kinase activity; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0030705 cytoskeleton-dependent intracellular transport; GO:0009653 anatomical structure morphogenesis; GO:0051646 mitochondrion localization; GO:0023057 negative regulation of signaling; GO:1902578 single-organism localization; GO:0010648 negative regulation of cell communication; GO:0051654 establishment of mitochondrion localization; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0007409 axonogenesis; GO:0051338 regulation of transferase activity; GO:0044248 cellular catabolic process; GO:0061061 muscle structure development; GO:1902580 single-organism cellular localization; GO:0001933 negative regulation of protein phosphorylation; GO:0007631 feeding behavior; GO:0007275 multicellular organism development; GO:0030534 adult behavior; GO:0009966 regulation of signal transduction; GO:1902531 regulation of intracellular signal transduction; GO:0006950 response to stress; GO:0048731 system development; GO:0098930 axonal transport; GO:0008283 cell proliferation; GO:0051656 establishment of organelle localization; GO:0044238 primary metabolic process; GO:0007017 microtubule-based process; GO:0009892 negative regulation of metabolic process; GO:0030182 neuron differentiation; GO:0043409 negative regulation of MAPK cascade; GO:0006928 movement of cell or subcellular component; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0051179 localization; GO:0043412 macromolecule modification; GO:0050905 neuromuscular process; GO:0045936 negative regulation of phosphate metabolic process; GO:0070646 protein modification by small protein removal; GO:0009968 negative regulation of signal transduction; GO:0048747 muscle fiber development; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0031400 negative regulation of protein modification process; GO:0051234 establishment of localization; GO:0002931 response to ischemia; GO:0010970 transport along microtubule; GO:0047497 mitochondrion transport along microtubule; GO:0051649 establishment of localization in cell; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0071901 negative regulation of protein serine/threonine kinase activity; GO:0032990 cell part morphogenesis; GO:0033673 negative regulation of kinase activity; GO:0048858 cell projection morphogenesis; GO:0007628 adult walking behavior; GO:0019896 axonal transport of mitochondrion; GO:0032502 developmental process; GO:0007600 sensory perception; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0051348 negative regulation of transferase activity; GO:0070647 protein modification by small protein conjugation or removal; GO:0010605 negative regulation of macromolecule metabolic process; GO:1902582 single-organism intracellular transport; GO:0008088 axo-dendritic transport; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0030030 cell projection organization; GO:0006469 negative regulation of protein kinase activity; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0090659 walking behavior; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0043549 regulation of kinase activity; GO:0045859 regulation of protein kinase activity; GO:0072384 organelle transport along microtubule; GO:0016043 cellular component organization; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0008344 adult locomotory behavior; GO:0043405 regulation of MAP kinase activity; GO:0060255 regulation of macromolecule metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0019233 sensory perception of pain; GO:0016579 protein deubiquitination; GO:0050896 response to stimulus; GO:0010498 proteasomal protein catabolic process; GO:0099111 microtubule-based transport; GO:0048468 cell development; GO:0000904 cell morphogenesis involved in differentiation; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0043408 regulation of MAPK cascade; GO:0042326 negative regulation of phosphorylation; GO:0006508 proteolysis; GO:0009987 cellular process; GO:0043632 modification-dependent macromolecule catabolic process; GO:0051146 striated muscle cell differentiation; GO:0044265 cellular macromolecule catabolic process; GO:0003008 system process; GO:0019941 modification-dependent protein catabolic process; GO:0001932 regulation of protein phosphorylation; GO:0048585 negative regulation of response to stimulus; GO:0031175 neuron projection development; GO:0051641 cellular localization; GO:0007018 microtubule-based movement; GO:0061564 axon development; GO:0042755 eating behavior; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0009057 macromolecule catabolic process; GO:0010563 negative regulation of phosphorus metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0042692 muscle cell differentiation; GO:0007626 locomotory behavior; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0099568 cytoplasmic region; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032838 cell projection cytoplasm; GO:0043025 neuronal cell body; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0043209 myelin sheath; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0044306 neuron projection terminus; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0005789 endoplasmic reticulum membrane; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0005576 extracellular region; GO:0033267 axon part; GO:0030424 axon; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:1904115 axon cytoplasm; GO:0036477 somatodendritic compartment; GO:0005634 nucleus; GO:0044432 endoplasmic reticulum part; GO:0044297 cell body; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0004843 thiol-dependent ubiquitin-specific protease activity; GO:0008238 exopeptidase activity; GO:0008233 peptidase activity; GO:0031625 ubiquitin protein ligase binding; GO:0005102 receptor binding; GO:0016874 ligase activity; GO:0019783 ubiquitin-like protein-specific protease activity; GO:0008234 cysteine-type peptidase activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0032182 ubiquitin-like protein binding; GO:0004175 endopeptidase activity; GO:0036459 thiol-dependent ubiquitinyl hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0031690 adrenergic receptor binding; GO:0043130 ubiquitin binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0101005 ubiquitinyl hydrolase activity; GO:0001664 G-protein coupled receptor binding; GO:0004197 cysteine-type endopeptidase activity; GO:0044389 ubiquitin-like protein ligase binding; GO:0031694 alpha-2A adrenergic receptor binding; GO:0008242 omega peptidase activity; GO:0019899 enzyme binding; ","K05611","UCHL1; ubiquitin carboxyl-terminal hydrolase L1 [EC:3.4.19.12]","hsa05012 Parkinson's disease - Homo sapiens (human); ","IPR001578; ","\"Peptidase C12, ubiquitin carboxyl-terminal hydrolase; \"\r"]
["P09960","Leukotriene A-4 hydrolase OS=Homo sapiens OX=9606 GN=LTA4H","LTA4H",69.284,125.44,31.1,16,29,16,0.965,1.001,1.002,1.003,0.985,1.007,1.009,0.552,"cytoplasm\r","GO:0006518 peptide metabolic process; GO:0045321 leukocyte activation; GO:0016053 organic acid biosynthetic process; GO:0019370 leukotriene biosynthetic process; GO:1901568 fatty acid derivative metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:0008610 lipid biosynthetic process; GO:0046456 icosanoid biosynthetic process; GO:0008152 metabolic process; GO:0043171 peptide catabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006690 icosanoid metabolic process; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0006629 lipid metabolic process; GO:0002443 leukocyte mediated immunity; GO:0002446 neutrophil mediated immunity; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006636 unsaturated fatty acid biosynthetic process; GO:0043603 cellular amide metabolic process; GO:0006633 fatty acid biosynthetic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0046394 carboxylic acid biosynthetic process; GO:0032940 secretion by cell; GO:0044710 single-organism metabolic process; GO:0043299 leukocyte degranulation; GO:0006082 organic acid metabolic process; GO:0043436 oxoacid metabolic process; GO:0033559 unsaturated fatty acid metabolic process; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0044248 cellular catabolic process; GO:0006508 proteolysis; GO:0034641 cellular nitrogen compound metabolic process; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0044711 single-organism biosynthetic process; GO:0016192 vesicle-mediated transport; GO:0006691 leukotriene metabolic process; GO:1901570 fatty acid derivative biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0002376 immune system process; GO:0006631 fatty acid metabolic process; GO:0044238 primary metabolic process; GO:0043312 neutrophil degranulation; GO:1901576 organic substance biosynthetic process; GO:0002263 cell activation involved in immune response; GO:0044249 cellular biosynthetic process; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:1901565 organonitrogen compound catabolic process; GO:0044283 small molecule biosynthetic process; GO:0019752 carboxylic acid metabolic process; GO:0001775 cell activation; GO:0006955 immune response; GO:0051179 localization; GO:0009056 catabolic process; GO:0072330 monocarboxylic acid biosynthetic process; GO:1901564 organonitrogen compound metabolic process; GO:0006887 exocytosis; ","GO:1904724 tertiary granule lumen; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0070820 tertiary granule; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0003723 RNA binding; GO:0016801 hydrolase activity, acting on ether bonds; GO:0008238 exopeptidase activity; GO:0008233 peptidase activity; GO:0043167 ion binding; GO:0070006 metalloaminopeptidase activity; GO:0008235 metalloexopeptidase activity; GO:0005515 protein binding; GO:0004177 aminopeptidase activity; GO:0008237 metallopeptidase activity; GO:0016787 hydrolase activity; GO:0033218 amide binding; GO:0008270 zinc ion binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0046914 transition metal ion binding; GO:0004463 leukotriene-A4 hydrolase activity; GO:0004301 epoxide hydrolase activity; GO:0042277 peptide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0016803 ether hydrolase activity; ","K01254","LTA4H; leukotriene-A4 hydrolase [EC:3.3.2.6]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00590 Arachidonic acid metabolism - Homo sapiens (human); ","IPR014782; IPR015211; IPR016024; ","\"Peptidase M1, membrane alanine aminopeptidase, N-terminal; Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal; Armadillo-type fold; \"\r"]
["P09972","Fructose-bisphosphate aldolase C OS=Homo sapiens OX=9606 GN=ALDOC","ALDOC",39.455,137.88,43.1,15,34,9,1.046,1.063,1.016,0.909,0.958,1.008,0.92,0.0616,"cytoplasm\r","GO:0009116 nucleoside metabolic process; GO:0045321 leukocyte activation; GO:0006165 nucleoside diphosphate phosphorylation; GO:0019362 pyridine nucleotide metabolic process; GO:0006096 glycolytic process; GO:0009185 ribonucleoside diphosphate metabolic process; GO:0044237 cellular metabolic process; GO:0006006 glucose metabolic process; GO:0008152 metabolic process; GO:0006094 gluconeogenesis; GO:0006091 generation of precursor metabolites and energy; GO:0032787 monocarboxylic acid metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0002443 leukocyte mediated immunity; GO:0009179 purine ribonucleoside diphosphate metabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0061620 glycolytic process through glucose-6-phosphate; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0006732 coenzyme metabolic process; GO:0005975 carbohydrate metabolic process; GO:0061718 glucose catabolic process to pyruvate; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0006000 fructose metabolic process; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0019674 NAD metabolic process; GO:0044710 single-organism metabolic process; GO:0009126 purine nucleoside monophosphate metabolic process; GO:0043436 oxoacid metabolic process; GO:0030855 epithelial cell differentiation; GO:0030388 fructose 1,6-bisphosphate metabolic process; GO:0016310 phosphorylation; GO:0002283 neutrophil activation involved in immune response; GO:0046496 nicotinamide nucleotide metabolic process; GO:0009259 ribonucleotide metabolic process; GO:0046364 monosaccharide biosynthetic process; GO:0006735 NADH regeneration; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0009119 ribonucleoside metabolic process; GO:0044711 single-organism biosynthetic process; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0002263 cell activation involved in immune response; GO:0006163 purine nucleotide metabolic process; GO:0045055 regulated exocytosis; GO:0006793 phosphorus metabolic process; GO:0044283 small molecule biosynthetic process; GO:0001775 cell activation; GO:0019637 organophosphate metabolic process; GO:0019320 hexose catabolic process; GO:0051179 localization; GO:0006955 immune response; GO:0019318 hexose metabolic process; GO:0006887 exocytosis; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0006757 ATP generation from ADP; GO:0046365 monosaccharide catabolic process; GO:0042278 purine nucleoside metabolic process; GO:0046031 ADP metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0019319 hexose biosynthetic process; GO:0048869 cellular developmental process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0046939 nucleotide phosphorylation; GO:0009135 purine nucleoside diphosphate metabolic process; GO:0072524 pyridine-containing compound metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0061615 glycolytic process through fructose-6-phosphate; GO:0051234 establishment of localization; GO:0006753 nucleoside phosphate metabolic process; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0009888 tissue development; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0055114 oxidation-reduction process; GO:0002446 neutrophil mediated immunity; GO:1901360 organic cyclic compound metabolic process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0051186 cofactor metabolic process; GO:0016052 carbohydrate catabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0032940 secretion by cell; GO:1901657 glycosyl compound metabolic process; GO:0043299 leukocyte degranulation; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:0016051 carbohydrate biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0002252 immune effector process; GO:0006734 NADH metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0061621 canonical glycolysis; GO:0006090 pyruvate metabolic process; GO:0030154 cell differentiation; GO:0005996 monosaccharide metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0036230 granulocyte activation; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0009132 nucleoside diphosphate metabolic process; GO:0046034 ATP metabolic process; GO:0044724 single-organism carbohydrate catabolic process; GO:0044712 single-organism catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044282 small molecule catabolic process; GO:0043312 neutrophil degranulation; GO:0002366 leukocyte activation involved in immune response; GO:0046128 purine ribonucleoside metabolic process; GO:0042119 neutrophil activation; GO:0006007 glucose catabolic process; GO:0044767 single-organism developmental process; GO:0019752 carboxylic acid metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0009056 catabolic process; ","GO:0034774 secretory granule lumen; GO:1904724 tertiary granule lumen; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0070820 tertiary granule; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0008092 cytoskeletal protein binding; GO:0004332 fructose-bisphosphate aldolase activity; GO:0003824 catalytic activity; GO:0016830 carbon-carbon lyase activity; GO:0005488 binding; GO:0016829 lyase activity; GO:0005515 protein binding; GO:0016832 aldehyde-lyase activity; ","K01623","ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]","hsa00051 Fructose and mannose metabolism - Homo sapiens (human); hsa04066 HIF-1 signaling pathway - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00030 Pentose phosphate pathway - Homo sapiens (human); hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human); hsa01230 Biosynthesis of amino acids - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); ","IPR013785; ","Aldolase-type TIM barrel; \r"]
["P0C0L4","Complement C4-A OS=Homo sapiens OX=9606 GN=C4A","C4A",192.78,46.791,37.6,57,123,3,1.043,0.982,1.219,0.89,1.082,0.91,0.888,0.257,"extracellular\r","GO:0060627 regulation of vesicle-mediated transport; GO:2000425 regulation of apoptotic cell clearance; GO:0016064 immunoglobulin mediated immune response; GO:0031347 regulation of defense response; GO:0051130 positive regulation of cellular component organization; GO:0006956 complement activation; GO:0010466 negative regulation of peptidase activity; GO:0008152 metabolic process; GO:0032879 regulation of localization; GO:0002250 adaptive immune response; GO:0006958 complement activation, classical pathway; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0050764 regulation of phagocytosis; GO:0002697 regulation of immune effector process; GO:0052548 regulation of endopeptidase activity; GO:0010468 regulation of gene expression; GO:0002443 leukocyte mediated immunity; GO:0080090 regulation of primary metabolic process; GO:0048522 positive regulation of cellular process; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0051050 positive regulation of transport; GO:0050776 regulation of immune response; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0006954 inflammatory response; GO:0048583 regulation of response to stimulus; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0002682 regulation of immune system process; GO:0006952 defense response; GO:1903317 regulation of protein maturation; GO:0052547 regulation of peptidase activity; GO:0050794 regulation of cellular process; GO:0030449 regulation of complement activation; GO:2000257 regulation of protein activation cascade; GO:0010951 negative regulation of endopeptidase activity; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0045807 positive regulation of endocytosis; GO:0002920 regulation of humoral immune response; GO:0002673 regulation of acute inflammatory response; GO:0006959 humoral immune response; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:2000427 positive regulation of apoptotic cell clearance; GO:0050896 response to stimulus; GO:0051346 negative regulation of hydrolase activity; GO:0045087 innate immune response; GO:0019724 B cell mediated immunity; GO:0071704 organic substance metabolic process; GO:0006508 proteolysis; GO:0002449 lymphocyte mediated immunity; GO:0050778 positive regulation of immune response; GO:0002253 activation of immune response; GO:0045861 negative regulation of proteolysis; GO:0030100 regulation of endocytosis; GO:0006950 response to stress; GO:0051049 regulation of transport; GO:0050766 positive regulation of phagocytosis; GO:0072376 protein activation cascade; GO:0032101 regulation of response to external stimulus; GO:0002376 immune system process; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0048518 positive regulation of biological process; GO:0051246 regulation of protein metabolic process; GO:0002684 positive regulation of immune system process; GO:0050727 regulation of inflammatory response; GO:0070613 regulation of protein processing; GO:0051248 negative regulation of protein metabolic process; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0051128 regulation of cellular component organization; GO:0048584 positive regulation of response to stimulus; GO:0006955 immune response; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0030425 dendrite; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0042995 cell projection; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0031982 vesicle; GO:0043025 neuronal cell body; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0045202 synapse; GO:0030424 axon; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0072562 blood microparticle; GO:0036477 somatodendritic compartment; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0044297 cell body; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043230 extracellular organelle; ","GO:0008233 peptidase activity; GO:0001849 complement component C1q binding; GO:0001846 opsonin binding; GO:0008236 serine-type peptidase activity; GO:0061134 peptidase regulator activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0004857 enzyme inhibitor activity; GO:0004866 endopeptidase inhibitor activity; GO:0004175 endopeptidase activity; GO:0004252 serine-type endopeptidase activity; GO:0030234 enzyme regulator activity; GO:0003824 catalytic activity; GO:0017171 serine hydrolase activity; GO:0005488 binding; GO:0030414 peptidase inhibitor activity; GO:0001848 complement binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0061135 endopeptidase regulator activity; ","K03989","C4; complement component 4","hsa05322 Systemic lupus erythematosus - Homo sapiens (human); hsa05133 Pertussis - Homo sapiens (human); hsa04610 Complement and coagulation cascades - Homo sapiens (human); hsa05150 Staphylococcus aureus infection - Homo sapiens (human); ","IPR008993; IPR001599; IPR011626; IPR000020; IPR002890; IPR011625; IPR009048; IPR001134; IPR001840; IPR008930; IPR018933; IPR019565; IPR018081; ","\"Tissue inhibitor of metalloproteinases-like, OB-fold; Alpha-2-macroglobulin; Alpha-macroglobulin complement component; Anaphylatoxin/fibulin; Alpha-2-macroglobulin, N-terminal; Alpha-2-macroglobulin, N-terminal 2; Alpha-macroglobulin, receptor-binding; Netrin domain; Anaphylatoxin, complement system domain; Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid; Netrin module, non-TIMP type; Alpha-2-macroglobulin, thiol-ester bond-forming; Anaphylatoxin, complement system; \"\r"]
["P0C0L5","Complement C4-B OS=Homo sapiens OX=9606 GN=C4B","C4B",192.75,323.31,38.3,58,129,4,0.969,0.891,1.041,1.025,1.028,1.019,1.059,0.319,"extracellular\r","GO:0060627 regulation of vesicle-mediated transport; GO:0009593 detection of chemical stimulus; GO:2000425 regulation of apoptotic cell clearance; GO:0016064 immunoglobulin mediated immune response; GO:0044699 single-organism process; GO:0098581 detection of external biotic stimulus; GO:0031347 regulation of defense response; GO:0009607 response to biotic stimulus; GO:0051234 establishment of localization; GO:0006909 phagocytosis; GO:0051130 positive regulation of cellular component organization; GO:0009605 response to external stimulus; GO:0006956 complement activation; GO:0010466 negative regulation of peptidase activity; GO:0008152 metabolic process; GO:0032879 regulation of localization; GO:0002250 adaptive immune response; GO:0051606 detection of stimulus; GO:0006958 complement activation, classical pathway; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0050764 regulation of phagocytosis; GO:0002697 regulation of immune effector process; GO:0044765 single-organism transport; GO:0052548 regulation of endopeptidase activity; GO:0010468 regulation of gene expression; GO:0002443 leukocyte mediated immunity; GO:0080090 regulation of primary metabolic process; GO:0002237 response to molecule of bacterial origin; GO:0048522 positive regulation of cellular process; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0051704 multi-organism process; GO:0008228 opsonization; GO:0051050 positive regulation of transport; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0006954 inflammatory response; GO:0048583 regulation of response to stimulus; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0002682 regulation of immune system process; GO:0006952 defense response; GO:1903317 regulation of protein maturation; GO:0052547 regulation of peptidase activity; GO:0050794 regulation of cellular process; GO:0030449 regulation of complement activation; GO:2000257 regulation of protein activation cascade; GO:0010951 negative regulation of endopeptidase activity; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0045807 positive regulation of endocytosis; GO:0002920 regulation of humoral immune response; GO:0002673 regulation of acute inflammatory response; GO:0006959 humoral immune response; GO:0043207 response to external biotic stimulus; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:2000427 positive regulation of apoptotic cell clearance; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0051346 negative regulation of hydrolase activity; GO:0045087 innate immune response; GO:0019724 B cell mediated immunity; GO:0071704 organic substance metabolic process; GO:0032490 detection of molecule of bacterial origin; GO:1902578 single-organism localization; GO:0006508 proteolysis; GO:0002449 lymphocyte mediated immunity; GO:0050778 positive regulation of immune response; GO:0009617 response to bacterium; GO:0002253 activation of immune response; GO:0045861 negative regulation of proteolysis; GO:0030100 regulation of endocytosis; GO:0006950 response to stress; GO:0051049 regulation of transport; GO:0016192 vesicle-mediated transport; GO:0009595 detection of biotic stimulus; GO:0050766 positive regulation of phagocytosis; GO:0072376 protein activation cascade; GO:0032101 regulation of response to external stimulus; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0006897 endocytosis; GO:0009892 negative regulation of metabolic process; GO:0048518 positive regulation of biological process; GO:0051246 regulation of protein metabolic process; GO:0002684 positive regulation of immune system process; GO:0050727 regulation of inflammatory response; GO:0070613 regulation of protein processing; GO:0051248 negative regulation of protein metabolic process; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0051128 regulation of cellular component organization; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0006955 immune response; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0030425 dendrite; GO:0044217 other organism part; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0042995 cell projection; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0044216 other organism cell; GO:0031982 vesicle; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0045202 synapse; GO:0030424 axon; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0072562 blood microparticle; GO:0036477 somatodendritic compartment; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0044215 other organism; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043230 extracellular organelle; ","GO:0008233 peptidase activity; GO:0008236 serine-type peptidase activity; GO:0061134 peptidase regulator activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0004866 endopeptidase inhibitor activity; GO:0004175 endopeptidase activity; GO:0004252 serine-type endopeptidase activity; GO:0030234 enzyme regulator activity; GO:0017171 serine hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0030414 peptidase inhibitor activity; GO:0001848 complement binding; GO:0030246 carbohydrate binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0061135 endopeptidase regulator activity; ","K03989","C4; complement component 4","hsa05322 Systemic lupus erythematosus - Homo sapiens (human); hsa05133 Pertussis - Homo sapiens (human); hsa04610 Complement and coagulation cascades - Homo sapiens (human); hsa05150 Staphylococcus aureus infection - Homo sapiens (human); ","IPR008993; IPR001599; IPR011626; IPR000020; IPR002890; IPR011625; IPR009048; IPR001134; IPR001840; IPR018933; IPR008930; IPR019565; IPR018081; ","\"Tissue inhibitor of metalloproteinases-like, OB-fold; Alpha-2-macroglobulin; Alpha-macroglobulin complement component; Anaphylatoxin/fibulin; Alpha-2-macroglobulin, N-terminal; Alpha-2-macroglobulin, N-terminal 2; Alpha-macroglobulin, receptor-binding; Netrin domain; Anaphylatoxin, complement system domain; Netrin module, non-TIMP type; Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid; Alpha-2-macroglobulin, thiol-ester bond-forming; Anaphylatoxin, complement system; \"\r"]
["P0C869","Cytosolic phospholipase A2 beta OS=Homo sapiens OX=9606 GN=PLA2G4B","PLA2G4B",87.977,13.751,5,3,3,3,0.917,1.163,0.835,1.116,0.978,1.006,1.063,0.548,"mitochondria\r","GO:0044700 single organism signaling; GO:0046470 phosphatidylcholine metabolic process; GO:0046486 glycerolipid metabolic process; GO:0022414 reproductive process; GO:0006654 phosphatidic acid biosynthetic process; GO:0008654 phospholipid biosynthetic process; GO:1901568 fatty acid derivative metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0030968 endoplasmic reticulum unfolded protein response; GO:0006796 phosphate-containing compound metabolic process; GO:0008610 lipid biosynthetic process; GO:0009395 phospholipid catabolic process; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0035966 response to topologically incorrect protein; GO:0007154 cell communication; GO:0044706 multi-multicellular organism process; GO:0006650 glycerophospholipid metabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0007567 parturition; GO:0070887 cellular response to chemical stimulus; GO:0006690 icosanoid metabolic process; GO:0006629 lipid metabolic process; GO:0051716 cellular response to stimulus; GO:0044281 small molecule metabolic process; GO:0036152 phosphatidylethanolamine acyl-chain remodeling; GO:0044763 single-organism cellular process; GO:0019932 second-messenger-mediated signaling; GO:0046473 phosphatidic acid metabolic process; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0090407 organophosphate biosynthetic process; GO:0006658 phosphatidylserine metabolic process; GO:1901575 organic substance catabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0044710 single-organism metabolic process; GO:0006954 inflammatory response; GO:0046474 glycerophospholipid biosynthetic process; GO:0006952 defense response; GO:0006082 organic acid metabolic process; GO:0046503 glycerolipid catabolic process; GO:0043436 oxoacid metabolic process; GO:0000003 reproduction; GO:0033559 unsaturated fatty acid metabolic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0019369 arachidonic acid metabolic process; GO:0035967 cellular response to topologically incorrect protein; GO:0034976 response to endoplasmic reticulum stress; GO:0046434 organophosphate catabolic process; GO:0071310 cellular response to organic substance; GO:0097164 ammonium ion metabolic process; GO:0036498 IRE1-mediated unfolded protein response; GO:0050896 response to stimulus; GO:0036151 phosphatidylcholine acyl-chain remodeling; GO:0071704 organic substance metabolic process; GO:0046471 phosphatidylglycerol metabolic process; GO:0036150 phosphatidylserine acyl-chain remodeling; GO:0019722 calcium-mediated signaling; GO:0006575 cellular modified amino acid metabolic process; GO:0046475 glycerophospholipid catabolic process; GO:0044248 cellular catabolic process; GO:0009987 cellular process; GO:0016042 lipid catabolic process; GO:0006986 response to unfolded protein; GO:0044711 single-organism biosynthetic process; GO:0034620 cellular response to unfolded protein; GO:0006950 response to stress; GO:0035556 intracellular signal transduction; GO:0044712 single-organism catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0006631 fatty acid metabolic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0045017 glycerolipid biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0001676 long-chain fatty acid metabolic process; GO:0044703 multi-organism reproductive process; GO:0019752 carboxylic acid metabolic process; GO:0044242 cellular lipid catabolic process; GO:0019637 organophosphate metabolic process; GO:0006644 phospholipid metabolic process; GO:0009056 catabolic process; GO:0036148 phosphatidylglycerol acyl-chain remodeling; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0005740 mitochondrial envelope; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0019866 organelle inner membrane; GO:0005768 endosome; GO:0031901 early endosome membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0010008 endosome membrane; GO:0098588 bounding membrane of organelle; GO:0044429 mitochondrial part; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031975 envelope; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0005544 calcium-dependent phospholipid binding; GO:0052689 carboxylic ester hydrolase activity; GO:0043167 ion binding; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0016298 lipase activity; GO:0047498 calcium-dependent phospholipase A2 activity; GO:0008970 phosphatidylcholine 1-acylhydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0005543 phospholipid binding; GO:0004623 phospholipase A2 activity; GO:0016788 hydrolase activity, acting on ester bonds; GO:0004620 phospholipase activity; GO:0004622 lysophospholipase activity; GO:0008289 lipid binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0005509 calcium ion binding; ","K16342","PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]","hsa04921 Oxytocin signaling pathway - Homo sapiens (human); hsa05231 Choline metabolism in cancer - Homo sapiens (human); hsa04072 Phospholipase D signaling pathway - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa04370 VEGF signaling pathway - Homo sapiens (human); hsa04014 Ras signaling pathway - Homo sapiens (human); hsa00590 Arachidonic acid metabolism - Homo sapiens (human); hsa04217 Necroptosis - Homo sapiens (human); hsa04270 Vascular smooth muscle contraction - Homo sapiens (human); hsa04010 MAPK signaling pathway - Homo sapiens (human); hsa04750 Inflammatory mediator regulation of TRP channels - Homo sapiens (human); hsa04726 Serotonergic synapse - Homo sapiens (human); hsa04724 Glutamatergic synapse - Homo sapiens (human); hsa00565 Ether lipid metabolism - Homo sapiens (human); hsa04666 Fc gamma R-mediated phagocytosis - Homo sapiens (human); hsa00591 Linoleic acid metabolism - Homo sapiens (human); hsa04664 Fc epsilon RI signaling pathway - Homo sapiens (human); hsa04913 Ovarian steroidogenesis - Homo sapiens (human); hsa04912 GnRH signaling pathway - Homo sapiens (human); hsa00592 alpha-Linolenic acid metabolism - Homo sapiens (human); hsa04730 Long-term depression - Homo sapiens (human); hsa04611 Platelet activation - Homo sapiens (human); hsa00564 Glycerophospholipid metabolism - Homo sapiens (human); ","IPR016035; IPR002642; IPR000008; ","\"Acyl transferase/acyl hydrolase/lysophospholipase; Lysophospholipase, catalytic domain; C2 domain; \"\r"]
["P0C870","JmjC domain-containing protein 7 OS=Homo sapiens OX=9606 GN=JMJD7","JMJD7",35.932,7.2368,7,2,2,2,0.894,1.319,0.928,0.879,1.032,0.966,0.916,0.606,"cyto_nucl\r",null,null,"GO:0005515 protein binding; GO:0005488 binding; ","K19219",null,null,"IPR003347; ","JmjC domain; \r"]
["P0CG08","Golgi pH regulator B OS=Homo sapiens OX=9606 GN=GPR89B","GPR89B",52.916,6.4507,2.4,1,4,1,0.995,1.048,1.005,1.115,0.866,0.966,0.967,0.632,"plasma membrane\r","GO:0065008 regulation of biological quality; GO:0006885 regulation of pH; GO:0045851 pH reduction; GO:0044070 regulation of anion transport; GO:0030003 cellular cation homeostasis; GO:0030641 regulation of cellular pH; GO:0030004 cellular monovalent inorganic cation homeostasis; GO:0044699 single-organism process; GO:0015031 protein transport; GO:0055082 cellular chemical homeostasis; GO:0051234 establishment of localization; GO:0042592 homeostatic process; GO:0055080 cation homeostasis; GO:0032879 regulation of localization; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0055067 monovalent inorganic cation homeostasis; GO:0050801 ion homeostasis; GO:0051049 regulation of transport; GO:0043269 regulation of ion transport; GO:0044763 single-organism cellular process; GO:0098771 inorganic ion homeostasis; GO:0019725 cellular homeostasis; GO:0071702 organic substance transport; GO:1903959 regulation of anion transmembrane transport; GO:0045184 establishment of protein localization; GO:0034762 regulation of transmembrane transport; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0034765 regulation of ion transmembrane transport; GO:0051453 regulation of intracellular pH; GO:0006873 cellular ion homeostasis; GO:0006811 ion transport; GO:0051452 intracellular pH reduction; GO:0051179 localization; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0032580 Golgi cisterna membrane; GO:0098588 bounding membrane of organelle; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0005795 Golgi stack; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098791 Golgi subcompartment; GO:0044431 Golgi apparatus part; GO:0043227 membrane-bounded organelle; GO:0005794 Golgi apparatus; GO:0031985 Golgi cisterna; GO:0044444 cytoplasmic part; GO:0031984 organelle subcompartment; ","GO:0015075 ion transmembrane transporter activity; GO:0022803 passive transmembrane transporter activity; GO:0005253 anion channel activity; GO:0022892 substrate-specific transporter activity; GO:0015267 channel activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0005244 voltage-gated ion channel activity; GO:0008308 voltage-gated anion channel activity; GO:0022838 substrate-specific channel activity; GO:0005216 ion channel activity; GO:0022836 gated channel activity; GO:0022832 voltage-gated channel activity; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; GO:0008509 anion transmembrane transporter activity; ",{"$nulls":3},"IPR022535; IPR025969; ","\"Golgi pH regulator, conserved domain; Abscisic acid G-protein coupled receptor-like domain; \"\r"]
["P0DI82","Trafficking protein particle complex subunit 2B OS=Homo sapiens OX=9606 GN=TRAPPC2B","TRAPPC2B",16.445,8.9673,15.7,2,3,2,1.152,0.643,0.961,1.138,1.169,0.933,1.176,0.376,"cytoplasm\r","GO:0046907 intracellular transport; GO:0006725 cellular aromatic compound metabolic process; GO:0097659 nucleic acid-templated transcription; GO:0048193 Golgi vesicle transport; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0018130 heterocycle biosynthetic process; GO:0016192 vesicle-mediated transport; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0006810 transport; GO:0016070 RNA metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0090304 nucleic acid metabolic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0006351 transcription, DNA-templated; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0051179 localization; GO:0006888 ER to Golgi vesicle-mediated transport; GO:1901362 organic cyclic compound biosynthetic process; ","GO:0043229 intracellular organelle; GO:0005783 endoplasmic reticulum; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0005793 endoplasmic reticulum-Golgi intermediate compartment; GO:0048471 perinuclear region of cytoplasm; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ",null,"K20301",null,null,"IPR011012; ","Longin-like domain; \r"]
["P0DMN0","Sulfotransferase 1A4 OS=Homo sapiens OX=9606 GN=SULT1A4","SULT1A4",34.196,7.0305,17.6,5,5,1,1.03,1.152,1.12,0.853,1.033,0.832,0.823,0.0599,"cytoplasm\r","GO:0006725 cellular aromatic compound metabolic process; GO:1901615 organic hydroxy compound metabolic process; GO:0008202 steroid metabolic process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0044699 single-organism process; GO:0009712 catechol-containing compound metabolic process; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0006584 catecholamine metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0044710 single-organism metabolic process; GO:0018958 phenol-containing compound metabolic process; GO:0009987 cellular process; GO:1901564 organonitrogen compound metabolic process; GO:0006629 lipid metabolic process; ","GO:0044424 intracellular part; GO:0005623 cell; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; ","GO:0004062 aryl sulfotransferase activity; GO:0008146 sulfotransferase activity; GO:0016782 transferase activity, transferring sulfur-containing groups; GO:0003824 catalytic activity; GO:0016740 transferase activity; ","K01014","SULT1A; aryl sulfotransferase [EC:2.8.2.1]","hsa05204 Chemical carcinogenesis - Homo sapiens (human); ","IPR000863; IPR027417; ","Sulfotransferase domain; P-loop containing nucleoside triphosphate hydrolase; \r"]
["P0DMV9","Heat shock 70 kDa protein 1B OS=Homo sapiens OX=9606 GN=HSPA1B","HSPA1B",70.051,323.31,50.2,29,104,13,1.05,1.046,1.057,0.954,0.956,0.951,0.907,4.54e-06,"cytoplasm\r","GO:0044409 entry into host; GO:0065008 regulation of biological quality; GO:0009116 nucleoside metabolic process; GO:0010941 regulation of cell death; GO:0045321 leukocyte activation; GO:0031116 positive regulation of microtubule polymerization; GO:0031347 regulation of defense response; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway; GO:0051240 positive regulation of multicellular organismal process; GO:0009408 response to heat; GO:0044093 positive regulation of molecular function; GO:0019693 ribose phosphate metabolic process; GO:0051493 regulation of cytoskeleton organization; GO:0090063 positive regulation of microtubule nucleation; GO:0044419 interspecies interaction between organisms; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0046718 viral entry into host cell; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:1901673 regulation of mitotic spindle assembly; GO:0080090 regulation of primary metabolic process; GO:0007088 regulation of mitotic nuclear division; GO:0044281 small molecule metabolic process; GO:0060760 positive regulation of response to cytokine stimulus; GO:0044763 single-organism cellular process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:1901099 negative regulation of signal transduction in absence of ligand; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0031323 regulation of cellular metabolic process; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0006810 transport; GO:0032886 regulation of microtubule-based process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0051092 positive regulation of NF-kappaB transcription factor activity; GO:0080135 regulation of cellular response to stress; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0051090 regulation of sequence-specific DNA binding transcription factor activity; GO:0044710 single-organism metabolic process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0060759 regulation of response to cytokine stimulus; GO:0031112 positive regulation of microtubule polymerization or depolymerization; GO:0048583 regulation of response to stimulus; GO:0010968 regulation of microtubule nucleation; GO:0010604 positive regulation of macromolecule metabolic process; GO:0090083 regulation of inclusion body assembly; GO:0002682 regulation of immune system process; GO:1902905 positive regulation of supramolecular fiber organization; GO:0009126 purine nucleoside monophosphate metabolic process; GO:0060548 negative regulation of cell death; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:1902903 regulation of supramolecular fiber organization; GO:0050794 regulation of cellular process; GO:2001239 regulation of extrinsic apoptotic signaling pathway in absence of ligand; GO:0033554 cellular response to stress; GO:0032677 regulation of interleukin-8 production; GO:0007346 regulation of mitotic cell cycle; GO:0070426 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway; GO:0002283 neutrophil activation involved in immune response; GO:0009259 ribonucleotide metabolic process; GO:0009628 response to abiotic stimulus; GO:0001819 positive regulation of cytokine production; GO:0051806 entry into cell of other organism involved in symbiotic interaction; GO:0031399 regulation of protein modification process; GO:0043067 regulation of programmed cell death; GO:0080134 regulation of response to stress; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0051239 regulation of multicellular organismal process; GO:0023057 negative regulation of signaling; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0010648 negative regulation of cell communication; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0051171 regulation of nitrogen compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0009119 ribonucleoside metabolic process; GO:0009966 regulation of signal transduction; GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; GO:1902531 regulation of intracellular signal transduction; GO:0006950 response to stress; GO:0051495 positive regulation of cytoskeleton organization; GO:0016192 vesicle-mediated transport; GO:0001961 positive regulation of cytokine-mediated signaling pathway; GO:0002376 immune system process; GO:0009141 nucleoside triphosphate metabolic process; GO:2001237 negative regulation of extrinsic apoptotic signaling pathway; GO:0044238 primary metabolic process; GO:0002263 cell activation involved in immune response; GO:0009892 negative regulation of metabolic process; GO:0006163 purine nucleotide metabolic process; GO:1903321 negative regulation of protein modification by small protein conjugation or removal; GO:0045055 regulated exocytosis; GO:0090224 regulation of spindle organization; GO:0006793 phosphorus metabolic process; GO:0001775 cell activation; GO:0019637 organophosphate metabolic process; GO:0031647 regulation of protein stability; GO:0051179 localization; GO:0006955 immune response; GO:0048584 positive regulation of response to stimulus; GO:0050821 protein stabilization; GO:0006887 exocytosis; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0032273 positive regulation of protein polymerization; GO:0009968 negative regulation of signal transduction; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0051129 negative regulation of cellular component organization; GO:0023051 regulation of signaling; GO:0009117 nucleotide metabolic process; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0070370 cellular heat acclimation; GO:0031110 regulation of microtubule polymerization or depolymerization; GO:0044764 multi-organism cellular process; GO:0060236 regulation of mitotic spindle organization; GO:1902115 regulation of organelle assembly; GO:0031400 negative regulation of protein modification process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0006457 protein folding; GO:0031396 regulation of protein ubiquitination; GO:0051130 positive regulation of cellular component organization; GO:2001141 regulation of RNA biosynthetic process; GO:2001233 regulation of apoptotic signaling pathway; GO:0051783 regulation of nuclear division; GO:0010646 regulation of cell communication; GO:0045088 regulation of innate immune response; GO:0009893 positive regulation of metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0006979 response to oxidative stress; GO:0032271 regulation of protein polymerization; GO:0031334 positive regulation of protein complex assembly; GO:0034599 cellular response to oxidative stress; GO:0051726 regulation of cell cycle; GO:0070887 cellular response to chemical stimulus; GO:0002274 myeloid leukocyte activation; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway; GO:0002446 neutrophil mediated immunity; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity; GO:0031113 regulation of microtubule polymerization; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0070434 positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway; GO:0030260 entry into host cell; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0043254 regulation of protein complex assembly; GO:0042221 response to chemical; GO:0010638 positive regulation of organelle organization; GO:0032940 secretion by cell; GO:0034605 cellular response to heat; GO:0070432 regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway; GO:0051828 entry into other organism involved in symbiotic interaction; GO:2001236 regulation of extrinsic apoptotic signaling pathway; GO:1900034 regulation of cellular response to heat; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0043299 leukocyte degranulation; GO:1901657 glycosyl compound metabolic process; GO:0042026 protein refolding; GO:0090084 negative regulation of inclusion body assembly; GO:0043069 negative regulation of programmed cell death; GO:0006725 cellular aromatic compound metabolic process; GO:0002252 immune effector process; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0019058 viral life cycle; GO:0001959 regulation of cytokine-mediated signaling pathway; GO:0044087 regulation of cellular component biogenesis; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0032757 positive regulation of interleukin-8 production; GO:0043066 negative regulation of apoptotic process; GO:0023056 positive regulation of signaling; GO:0016032 viral process; GO:0009266 response to temperature stimulus; GO:0034641 cellular nitrogen compound metabolic process; GO:0036230 granulocyte activation; GO:0010647 positive regulation of cell communication; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0009987 cellular process; GO:0046034 ATP metabolic process; GO:0031397 negative regulation of protein ubiquitination; GO:0070507 regulation of microtubule cytoskeleton organization; GO:0010286 heat acclimation; GO:0006355 regulation of transcription, DNA-templated; GO:0006807 nitrogen compound metabolic process; GO:0033043 regulation of organelle organization; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0043312 neutrophil degranulation; GO:0051701 interaction with host; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0002366 leukocyte activation involved in immune response; GO:0046128 purine ribonucleoside metabolic process; GO:0042119 neutrophil activation; GO:0090169 regulation of spindle assembly; GO:0051246 regulation of protein metabolic process; GO:0002684 positive regulation of immune system process; GO:0001817 regulation of cytokine production; GO:0051248 negative regulation of protein metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0009967 positive regulation of signal transduction; GO:0051128 regulation of cellular component organization; GO:0044089 positive regulation of cellular component biogenesis; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0044421 extracellular region part; GO:0005615 extracellular space; GO:0044450 microtubule organizing center part; GO:0031410 cytoplasmic vesicle; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0031974 membrane-enclosed lumen; GO:0101002 ficolin-1-rich granule; GO:0005815 microtubule organizing center; GO:0005654 nucleoplasm; GO:0005925 focal adhesion; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0005912 adherens junction; GO:0048471 perinuclear region of cytoplasm; GO:0030055 cell-substrate junction; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0016234 inclusion body; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0072562 blood microparticle; GO:0005634 nucleus; GO:0005813 centrosome; GO:0005814 centriole; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0055131 C3HC4-type RING finger domain binding; GO:1901265 nucleoside phosphate binding; GO:0031625 ubiquitin protein ligase binding; GO:0005102 receptor binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0044183 protein binding involved in protein folding; GO:0016887 ATPase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0042826 histone deacetylase binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0001664 G-protein coupled receptor binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0031072 heat shock protein binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0001618 virus receptor activity; GO:0032549 ribonucleoside binding; GO:0060089 molecular transducer activity; GO:0097367 carbohydrate derivative binding; GO:0004872 receptor activity; GO:0042623 ATPase activity, coupled; GO:0019904 protein domain specific binding; GO:0032555 purine ribonucleotide binding; GO:0051082 unfolded protein binding; GO:0001883 purine nucleoside binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0019899 enzyme binding; GO:0036094 small molecule binding; ","K03283","HSPA1s; heat shock 70kDa protein 1/2/6/8","hsa03040 Spliceosome - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); hsa05020 Prion diseases - Homo sapiens (human); hsa05162 Measles - Homo sapiens (human); hsa05134 Legionellosis - Homo sapiens (human); hsa04010 MAPK signaling pathway - Homo sapiens (human); hsa04144 Endocytosis - Homo sapiens (human); hsa04612 Antigen processing and presentation - Homo sapiens (human); hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); hsa04213 Longevity regulating pathway - multiple species - Homo sapiens (human); hsa04915 Estrogen signaling pathway - Homo sapiens (human); hsa05145 Toxoplasmosis - Homo sapiens (human); hsa05164 Influenza A - Homo sapiens (human); ","IPR029048; IPR029047; ","\"Heat shock protein 70kD, C-terminal domain; Heat shock protein 70kD, peptide-binding domain; \"\r"]
["P0DN76","Splicing factor U2AF 35 kDa subunit-like protein OS=Homo sapiens OX=9606 GN=U2AF1L5","U2AF1L5",27.872,18.01,21.7,5,6,5,0.927,0.922,0.787,1.185,1.182,1.126,1.325,0.00722,"nucleus\r","GO:0006396 RNA processing; GO:0006725 cellular aromatic compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0008152 metabolic process; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0090304 nucleic acid metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0009987 cellular process; GO:0008380 RNA splicing; GO:0016071 mRNA metabolic process; ","GO:0043229 intracellular organelle; GO:0089701 U2AF; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0043234 protein complex; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:1901265 nucleoside phosphate binding; GO:0005488 binding; GO:0043167 ion binding; GO:0003676 nucleic acid binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0000166 nucleotide binding; GO:0036094 small molecule binding; ","K12836","U2AF1; splicing factor U2AF 35 kDa subunit","hsa03040 Spliceosome - Homo sapiens (human); hsa05131 Shigellosis - Homo sapiens (human); ","IPR000571; IPR000504; IPR012677; IPR003954; ","\"Zinc finger, CCCH-type; RNA recognition motif domain; Nucleotide-binding alpha-beta plait domain; RNA recognition motif domain, eukaryote; \"\r"]
["P0DOX3","Immunoglobulin delta heavy chain OS=Homo sapiens OX=9606","---",56.224,34.537,18.9,7,9,7,0.947,0.97,0.98,1.028,1.108,1.036,1.095,0.0252,"nucleus\r",null,null,"GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR007110; IPR013783; IPR003599; IPR013106; IPR013151; IPR003597; ","Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin subtype; Immunoglobulin V-set domain; Immunoglobulin; Immunoglobulin C1-set; \r"]
["P0DOX5","Immunoglobulin gamma-1 heavy chain OS=Homo sapiens OX=9606","---",48.986,323.31,48.6,16,143,8,0.952,0.98,0.996,1.029,1.026,1.051,1.061,0.0178,"mitochondria\r",null,null,"GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR007110; IPR013783; IPR013106; IPR003599; IPR003597; ","Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin V-set domain; Immunoglobulin subtype; Immunoglobulin C1-set; \r"]
["P0DOX7","Immunoglobulin kappa light chain OS=Homo sapiens OX=9606","---",23.379,241.56,53.7,7,64,3,1.013,0.971,0.998,0.955,1.029,0.943,0.982,0.556,"nucleus\r",null,null,"GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR007110; IPR013783; IPR013106; IPR003599; IPR003597; ","Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin V-set domain; Immunoglobulin subtype; Immunoglobulin C1-set; \r"]
["P0DOX8","Immunoglobulin lambda-1 light chain OS=Homo sapiens OX=9606","---",22.83,158.38,41.7,8,51,3,0.938,0.961,0.929,1.02,1.086,1.035,1.111,0.00816,"nucleus\r",null,null,"GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR007110; IPR013783; IPR003599; IPR013106; IPR003597; ","Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin subtype; Immunoglobulin V-set domain; Immunoglobulin C1-set; \r"]
["P0DOY3","Immunoglobulin lambda constant 3 OS=Homo sapiens OX=9606 GN=IGLC3","IGLC3",11.265,55.135,69.8,6,48,2,0.927,0.857,0.982,1.07,1.087,1.002,1.142,0.0456,"extracellular\r",null,null,"GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR007110; IPR013783; IPR003597; ","Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin C1-set; \r"]
["P0DP03","Immunoglobulin heavy variable 3-30-5 OS=Homo sapiens OX=9606 GN=IGHV3-30-5","IGHV3-30-5",12.947,7.2113,15.4,2,5,1,0.995,1.059,1.031,0.889,1.092,0.941,0.947,0.417,"extracellular\r",null,null,"GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR007110; IPR013783; IPR013106; ","Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin V-set domain; \r"]
["P0DP04","Immunoglobulin heavy variable 3-43D OS=Homo sapiens OX=9606 GN=IGHV3-43D","IGHV3-43D",13.017,10.36,9.3,1,4,1,0.9,1.044,0.869,0.984,1.178,1.025,1.133,0.185,"extracellular\r",null,null,"GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR007110; IPR013783; IPR013106; ","Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin V-set domain; \r"]
["P0DP08","Immunoglobulin heavy variable 4-38-2 OS=Homo sapiens OX=9606 GN=IGHV4-38-2","IGHV4-38-2",13.016,13.495,21.4,2,4,1,0.993,0.891,0.917,1.161,1.06,0.983,1.144,0.0834,"extracellular\r",null,null,"GO:0005515 protein binding; GO:0005488 binding; ","K06856","IGH; immunoglobulin heavy chain","hsa05330 Allograft rejection - Homo sapiens (human); hsa05322 Systemic lupus erythematosus - Homo sapiens (human); hsa04672 Intestinal immune network for IgA production - Homo sapiens (human); hsa04072 Phospholipase D signaling pathway - Homo sapiens (human); hsa05152 Tuberculosis - Homo sapiens (human); hsa05150 Staphylococcus aureus infection - Homo sapiens (human); hsa04650 Natural killer cell mediated cytotoxicity - Homo sapiens (human); hsa05323 Rheumatoid arthritis - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); hsa04662 B cell receptor signaling pathway - Homo sapiens (human); hsa05140 Leishmaniasis - Homo sapiens (human); hsa04640 Hematopoietic cell lineage - Homo sapiens (human); hsa04020 Calcium signaling pathway - Homo sapiens (human); hsa05162 Measles - Homo sapiens (human); hsa05340 Primary immunodeficiency - Homo sapiens (human); hsa05320 Autoimmune thyroid disease - Homo sapiens (human); hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human); hsa04666 Fc gamma R-mediated phagocytosis - Homo sapiens (human); hsa04664 Fc epsilon RI signaling pathway - Homo sapiens (human); hsa05414 Dilated cardiomyopathy (DCM) - Homo sapiens (human); hsa05310 Asthma - Homo sapiens (human); hsa05416 Viral myocarditis - Homo sapiens (human); hsa05146 Amoebiasis - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); hsa05143 African trypanosomiasis - Homo sapiens (human); hsa04064 NF-kappa B signaling pathway - Homo sapiens (human); ","IPR007110; IPR013783; IPR013106; ","Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin V-set domain; \r"]
["P0DP25","Calmodulin-3 OS=Homo sapiens OX=9606 GN=CALM3","CALM3",16.837,88.067,47,9,31,8,1.046,1.028,1.024,0.971,0.985,0.947,0.937,7.92E-3,"\"cytoplasm,nucleus\"\r",null,null,"GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005509 calcium ion binding; GO:0005488 binding; GO:0043167 ion binding; ","K02183","CALM; calmodulin","hsa05152 Tuberculosis - Homo sapiens (human); hsa04015 Rap1 signaling pathway - Homo sapiens (human); hsa04625 C-type lectin receptor signaling pathway - Homo sapiens (human); hsa04014 Ras signaling pathway - Homo sapiens (human); hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human); hsa04924 Renin secretion - Homo sapiens (human); hsa04970 Salivary secretion - Homo sapiens (human); hsa04114 Oocyte meiosis - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa04070 Phosphatidylinositol signaling system - Homo sapiens (human); hsa04922 Glucagon signaling pathway - Homo sapiens (human); hsa05034 Alcoholism - Homo sapiens (human); hsa04971 Gastric acid secretion - Homo sapiens (human); hsa04744 Phototransduction - Homo sapiens (human); hsa04915 Estrogen signaling pathway - Homo sapiens (human); hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04921 Oxytocin signaling pathway - Homo sapiens (human); hsa04218 Cellular senescence - Homo sapiens (human); hsa04728 Dopaminergic synapse - Homo sapiens (human); hsa04371 Apelin signaling pathway - Homo sapiens (human); hsa04722 Neurotrophin signaling pathway - Homo sapiens (human); hsa05031 Amphetamine addiction - Homo sapiens (human); hsa04910 Insulin signaling pathway - Homo sapiens (human); hsa04916 Melanogenesis - Homo sapiens (human); hsa04020 Calcium signaling pathway - Homo sapiens (human); hsa05167 Kaposi's sarcoma-associated herpesvirus infection - Homo sapiens (human); hsa04270 Vascular smooth muscle contraction - Homo sapiens (human); hsa04024 cAMP signaling pathway - Homo sapiens (human); hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human); hsa04750 Inflammatory mediator regulation of TRP channels - Homo sapiens (human); hsa04925 Aldosterone synthesis and secretion - Homo sapiens (human); hsa04740 Olfactory transduction - Homo sapiens (human); hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human); hsa04912 GnRH signaling pathway - Homo sapiens (human); hsa05214 Glioma - Homo sapiens (human); hsa05133 Pertussis - Homo sapiens (human); hsa04720 Long-term potentiation - Homo sapiens (human); hsa04713 Circadian entrainment - Homo sapiens (human); ","IPR002048; IPR011992; ","EF-hand domain; EF-hand domain pair; \r"]
["P0DP57","Secreted Ly-6/uPAR domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SLURP2","SLURP2",10.16,12.578,13.4,1,1,1,0.683,0.635,0.681,1.345,1.375,1.247,1.984,5.78e-05,"extracellular\r",{"$nulls":6},"IPR016054; ","Ly-6 antigen/uPA receptor-like; \r"]
["P10109","Adrenodoxin, mitochondrial OS=Homo sapiens OX=9606 GN=FDX1","FDX1",19.393,3.4296,8.7,2,2,2,1.013,1.053,1.066,0.97,0.913,0.998,0.92,0.0508,"mitochondria\r","GO:0042446 hormone biosynthetic process; GO:0065008 regulation of biological quality; GO:1901615 organic hydroxy compound metabolic process; GO:1902652 secondary alcohol metabolic process; GO:0006066 alcohol metabolic process; GO:0071310 cellular response to organic substance; GO:1901700 response to oxygen-containing compound; GO:0046683 response to organophosphorus; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0050896 response to stimulus; GO:0008207 C21-steroid hormone metabolic process; GO:0044237 cellular metabolic process; GO:0016125 sterol metabolic process; GO:0008610 lipid biosynthetic process; GO:0071704 organic substance metabolic process; GO:0033993 response to lipid; GO:0008152 metabolic process; GO:0014074 response to purine-containing compound; GO:0009719 response to endogenous stimulus; GO:0009987 cellular process; GO:0070887 cellular response to chemical stimulus; GO:0006629 lipid metabolic process; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0042445 hormone metabolic process; GO:0008203 cholesterol metabolic process; GO:1901655 cellular response to ketone; GO:1904322 cellular response to forskolin; GO:0044711 single-organism biosynthetic process; GO:0055114 oxidation-reduction process; GO:0071320 cellular response to cAMP; GO:1904321 response to forskolin; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0008202 steroid metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0071407 cellular response to organic cyclic compound; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0071396 cellular response to lipid; GO:0034754 cellular hormone metabolic process; GO:0006694 steroid biosynthetic process; GO:0071417 cellular response to organonitrogen compound; GO:0010243 response to organonitrogen compound; GO:0042221 response to chemical; GO:1901701 cellular response to oxygen-containing compound; GO:0051591 response to cAMP; GO:1901699 cellular response to nitrogen compound; GO:0071495 cellular response to endogenous stimulus; GO:0044710 single-organism metabolic process; GO:1901698 response to nitrogen compound; GO:0010817 regulation of hormone levels; GO:0006700 C21-steroid hormone biosynthetic process; GO:1901362 organic cyclic compound biosynthetic process; GO:1901654 response to ketone; GO:0065007 biological regulation; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0009055 electron carrier activity; GO:0051537 2 iron, 2 sulfur cluster binding; GO:0005506 iron ion binding; GO:0046914 transition metal ion binding; GO:0005488 binding; GO:0051536 iron-sulfur cluster binding; GO:0043167 ion binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0051540 metal cluster binding; ",{"$nulls":3},"IPR001041; IPR012675; ","2Fe-2S ferredoxin-type iron-sulfur binding domain; Beta-grasp domain; \r"]
["P10155","60 kDa SS-A/Ro ribonucleoprotein OS=Homo sapiens OX=9606 GN=TROVE2","TROVE2",60.67,57.229,28.6,15,21,15,1.032,1.007,0.971,1.023,0.951,1.012,0.992,0.79,"cytoplasm\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0007166 cell surface receptor signaling pathway; GO:0097659 nucleic acid-templated transcription; GO:0060271 cilium assembly; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0007224 smoothened signaling pathway; GO:0044782 cilium organization; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0009314 response to radiation; GO:0043170 macromolecule metabolic process; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0002520 immune system development; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0016070 RNA metabolic process; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0030030 cell projection organization; GO:0044260 cellular macromolecule metabolic process; GO:0048856 anatomical structure development; GO:1901362 organic cyclic compound biosynthetic process; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0006725 cellular aromatic compound metabolic process; GO:0009628 response to abiotic stimulus; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:0070925 organelle assembly; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0009416 response to light stimulus; GO:0048731 system development; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0030031 cell projection assembly; GO:0044249 cellular biosynthetic process; GO:0009411 response to UV; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044767 single-organism developmental process; GO:0006996 organelle organization; GO:0010467 gene expression; GO:0006383 transcription from RNA polymerase III promoter; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0043167 ion binding; GO:0003676 nucleic acid binding; GO:0030620 U2 snRNA binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0017069 snRNA binding; ","K11089","TROVE2; 60 kDa SS-A/Ro ribonucleoprotein","hsa05322 Systemic lupus erythematosus - Homo sapiens (human); ","IPR008858; IPR002035; ","\"TROVE domain; von Willebrand factor, type A; \"\r"]
["P10253","Lysosomal alpha-glucosidase OS=Homo sapiens OX=9606 GN=GAA","GAA",105.32,33.443,10,9,13,9,1.078,1.043,1.115,0.927,0.964,0.87,0.853,0.011,"extracellular\r","GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0044237 cellular metabolic process; GO:0050877 neurological system process; GO:0044264 cellular polysaccharide metabolic process; GO:0007610 behavior; GO:0006006 glucose metabolic process; GO:0008152 metabolic process; GO:0007507 heart development; GO:0006091 generation of precursor metabolites and energy; GO:0005985 sucrose metabolic process; GO:0044262 cellular carbohydrate metabolic process; GO:0044057 regulation of system process; GO:0043170 macromolecule metabolic process; GO:0051651 maintenance of location in cell; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0002443 leukocyte mediated immunity; GO:0044281 small molecule metabolic process; GO:0050879 multicellular organismal movement; GO:0044763 single-organism cellular process; GO:0006941 striated muscle contraction; GO:0005975 carbohydrate metabolic process; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0048513 animal organ development; GO:0044710 single-organism metabolic process; GO:0046716 muscle cell cellular homeostasis; GO:0044260 cellular macromolecule metabolic process; GO:0009887 animal organ morphogenesis; GO:0003015 heart process; GO:0003013 circulatory system process; GO:0072359 circulatory system development; GO:0044707 single-multicellular organism process; GO:0002283 neutrophil activation involved in immune response; GO:0044275 cellular carbohydrate catabolic process; GO:0044042 glucan metabolic process; GO:0051239 regulation of multicellular organismal process; GO:0060249 anatomical structure homeostasis; GO:0009653 anatomical structure morphogenesis; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0044248 cellular catabolic process; GO:0007275 multicellular organism development; GO:0050885 neuromuscular process controlling balance; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0005977 glycogen metabolic process; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:0002263 cell activation involved in immune response; GO:0003009 skeletal muscle contraction; GO:0045055 regulated exocytosis; GO:0003011 involuntary skeletal muscle contraction; GO:0006996 organelle organization; GO:0080171 lytic vacuole organization; GO:0001775 cell activation; GO:0006955 immune response; GO:0051179 localization; GO:0050905 neuromuscular process; GO:0006887 exocytosis; GO:0019318 hexose metabolic process; GO:0003012 muscle system process; GO:0044699 single-organism process; GO:0005984 disaccharide metabolic process; GO:0051234 establishment of localization; GO:0005980 glycogen catabolic process; GO:0007033 vacuole organization; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:0009251 glucan catabolic process; GO:0009888 tissue development; GO:0006073 cellular glucan metabolic process; GO:0055114 oxidation-reduction process; GO:0003016 respiratory system process; GO:0003007 heart morphogenesis; GO:0002446 neutrophil mediated immunity; GO:0019725 cellular homeostasis; GO:0002444 myeloid leukocyte mediated immunity; GO:0016052 carbohydrate catabolic process; GO:0007040 lysosome organization; GO:0044723 single-organism carbohydrate metabolic process; GO:0050789 regulation of biological process; GO:0032940 secretion by cell; GO:0015980 energy derivation by oxidation of organic compounds; GO:0043299 leukocyte degranulation; GO:0048856 anatomical structure development; GO:0043181 vacuolar sequestering; GO:0016043 cellular component organization; GO:0000023 maltose metabolic process; GO:0002252 immune effector process; GO:1903522 regulation of blood circulation; GO:0006112 energy reserve metabolic process; GO:0060048 cardiac muscle contraction; GO:0008016 regulation of heart contraction; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0050884 neuromuscular process controlling posture; GO:0006936 muscle contraction; GO:0005976 polysaccharide metabolic process; GO:0005996 monosaccharide metabolic process; GO:0008015 blood circulation; GO:0050881 musculoskeletal movement; GO:0051235 maintenance of location; GO:0009311 oligosaccharide metabolic process; GO:0036230 granulocyte activation; GO:0060047 heart contraction; GO:0009987 cellular process; GO:0044724 single-organism carbohydrate catabolic process; GO:0003008 system process; GO:0002086 diaphragm contraction; GO:0044712 single-organism catabolic process; GO:0044247 cellular polysaccharide catabolic process; GO:0000272 polysaccharide catabolic process; GO:0043312 neutrophil degranulation; GO:0051641 cellular localization; GO:0002366 leukocyte activation involved in immune response; GO:0007585 respiratory gaseous exchange; GO:0042119 neutrophil activation; GO:0044767 single-organism developmental process; GO:0009057 macromolecule catabolic process; GO:0007626 locomotory behavior; GO:0002026 regulation of the force of heart contraction; GO:0009056 catabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070821 tertiary granule membrane; GO:0005775 vacuolar lumen; GO:0031974 membrane-enclosed lumen; GO:0005765 lysosomal membrane; GO:0070062 extracellular exosome; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0005764 lysosome; GO:0098805 whole membrane; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0070820 tertiary granule; GO:0044446 intracellular organelle part; GO:0035577 azurophil granule membrane; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0043202 lysosomal lumen; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0042582 azurophil granule; GO:0030659 cytoplasmic vesicle membrane; GO:0098852 lytic vacuole membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0030667 secretory granule membrane; GO:0101003 ficolin-1-rich granule membrane; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0090599 alpha-glucosidase activity; GO:0004558 alpha-1,4-glucosidase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016798 hydrolase activity, acting on glycosyl bonds; GO:0015926 glucosidase activity; GO:0030246 carbohydrate binding; GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds; GO:0016787 hydrolase activity; GO:0032450 maltose alpha-glucosidase activity; GO:0004574 oligo-1,6-glucosidase activity; ","K12316","GAA; lysosomal alpha-glucosidase [EC:3.2.1.20]","hsa04142 Lysosome - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00500 Starch and sucrose metabolism - Homo sapiens (human); hsa00052 Galactose metabolism - Homo sapiens (human); ","IPR011013; IPR031727; IPR025887; IPR000519; IPR017853; ","\"Galactose mutarotase-like domain; Galactose mutarotase, N-terminal barrel; Glycoside hydrolase family 31, N-terminal domain; P-type trefoil domain; Glycoside hydrolase superfamily; \"\r"]
["P10301","Ras-related protein R-Ras OS=Homo sapiens OX=9606 GN=RRAS","RRAS",23.48,25.094,34.9,6,11,4,1.053,1.079,1.071,0.96,0.857,0.941,0.861,0.0135,"nucleus\r","GO:0044700 single organism signaling; GO:0051896 regulation of protein kinase B signaling; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0040013 negative regulation of locomotion; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:1904018 positive regulation of vasculature development; GO:0060322 head development; GO:0032502 developmental process; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:0002521 leukocyte differentiation; GO:0044763 single-organism cellular process; GO:0002520 immune system development; GO:0007264 small GTPase mediated signal transduction; GO:2000146 negative regulation of cell motility; GO:0031323 regulation of cellular metabolic process; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0048513 animal organ development; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0048583 regulation of response to stimulus; GO:0019222 regulation of metabolic process; GO:0045765 regulation of angiogenesis; GO:0019220 regulation of phosphate metabolic process; GO:0010171 body morphogenesis; GO:0060325 face morphogenesis; GO:0051094 positive regulation of developmental process; GO:0048856 anatomical structure development; GO:0007265 Ras protein signal transduction; GO:0051271 negative regulation of cellular component movement; GO:2000026 regulation of multicellular organismal development; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0060324 face development; GO:0060255 regulation of macromolecule metabolic process; GO:0031399 regulation of protein modification process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:0045766 positive regulation of angiogenesis; GO:0051239 regulation of multicellular organismal process; GO:0009653 anatomical structure morphogenesis; GO:0030154 cell differentiation; GO:0070372 regulation of ERK1 and ERK2 cascade; GO:0043408 regulation of MAPK cascade; GO:0060323 head morphogenesis; GO:2000145 regulation of cell motility; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:1902531 regulation of intracellular signal transduction; GO:0035556 intracellular signal transduction; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:1901342 regulation of vasculature development; GO:0001932 regulation of protein phosphorylation; GO:0030334 regulation of cell migration; GO:0002376 immune system process; GO:0048518 positive regulation of biological process; GO:0048534 hematopoietic or lymphoid organ development; GO:0030097 hemopoiesis; GO:0030336 negative regulation of cell migration; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0040012 regulation of locomotion; GO:0050793 regulation of developmental process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0070161 anchoring junction; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0005924 cell-substrate adherens junction; ","GO:1901265 nucleoside phosphate binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0019003 GDP binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0003924 GTPase activity; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0017076 purine nucleotide binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0044877 macromolecular complex binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0032561 guanyl ribonucleotide binding; GO:0036094 small molecule binding; GO:0032403 protein complex binding; ","K07829","RRAS; Ras-related protein R-Ras","hsa04072 Phospholipase D signaling pathway - Homo sapiens (human); hsa04015 Rap1 signaling pathway - Homo sapiens (human); hsa04218 Cellular senescence - Homo sapiens (human); hsa04625 C-type lectin receptor signaling pathway - Homo sapiens (human); hsa04371 Apelin signaling pathway - Homo sapiens (human); hsa04137 Mitophagy - animal - Homo sapiens (human); hsa04014 Ras signaling pathway - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa04024 cAMP signaling pathway - Homo sapiens (human); hsa04010 MAPK signaling pathway - Homo sapiens (human); hsa05166 HTLV-I infection - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa04360 Axon guidance - Homo sapiens (human); hsa04140 Autophagy - animal - Homo sapiens (human); ","IPR005225; IPR027417; ","Small GTP-binding protein domain; P-loop containing nucleoside triphosphate hydrolase; \r"]
["P10412","Histone H1.4 OS=Homo sapiens OX=9606 GN=HIST1H1E","HIST1H1E",21.865,41.603,30.6,9,16,6,1.123,1.019,1.076,0.927,0.917,0.971,0.875,0.0158,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0051253 negative regulation of RNA metabolic process; GO:0044237 cellular metabolic process; GO:0032259 methylation; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0008213 protein alkylation; GO:0006334 nucleosome assembly; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0031497 chromatin assembly; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0071824 protein-DNA complex subunit organization; GO:0071103 DNA conformation change; GO:0098532 histone H3-K27 trimethylation; GO:0010468 regulation of gene expression; GO:0006333 chromatin assembly or disassembly; GO:0031326 regulation of cellular biosynthetic process; GO:0051568 histone H3-K4 methylation; GO:0080090 regulation of primary metabolic process; GO:0000122 negative regulation of transcription from RNA polymerase II promoter; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0018022 peptidyl-lysine methylation; GO:0065004 protein-DNA complex assembly; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:1902679 negative regulation of RNA biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006464 cellular protein modification process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0006325 chromatin organization; GO:0080182 histone H3-K4 trimethylation; GO:0036211 protein modification process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0016571 histone methylation; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0034728 nucleosome organization; GO:0060255 regulation of macromolecule metabolic process; GO:0016570 histone modification; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0071704 organic substance metabolic process; GO:0018205 peptidyl-lysine modification; GO:0045892 negative regulation of transcription, DNA-templated; GO:0070734 histone H3-K27 methylation; GO:0006323 DNA packaging; GO:0006479 protein methylation; GO:0034968 histone lysine methylation; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0018023 peptidyl-lysine trimethylation; GO:0016569 covalent chromatin modification; GO:0009987 cellular process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0034622 cellular macromolecular complex assembly; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0018193 peptidyl-amino acid modification; GO:0009890 negative regulation of biosynthetic process; GO:0051276 chromosome organization; GO:0043414 macromolecule methylation; GO:0006996 organelle organization; GO:0016584 nucleosome positioning; GO:0031327 negative regulation of cellular biosynthetic process; GO:0043412 macromolecule modification; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0000792 heterochromatin; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0070013 intracellular organelle lumen; GO:0044454 nuclear chromosome part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0000790 nuclear chromatin; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0044815 DNA packaging complex; GO:0032993 protein-DNA complex; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005576 extracellular region; GO:0000786 nucleosome; GO:0005720 nuclear heterochromatin; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0000785 chromatin; GO:0000228 nuclear chromosome; GO:0043230 extracellular organelle; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003677 DNA binding; GO:0003723 RNA binding; GO:0005515 protein binding; GO:0003682 chromatin binding; GO:0031490 chromatin DNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; ","K11275",null,null,"IPR011991; IPR005818; ","\"Winged helix-turn-helix DNA-binding domain; Linker histone H1/H5, domain H15; \"\r"]
["P10415","Apoptosis regulator Bcl-2 OS=Homo sapiens OX=9606 GN=BCL2","BCL2",26.266,3.5702,4.2,1,1,1,1.046,1.106,1.246,0.816,0.84,0.963,0.771,0.023,"plasma membrane\r",{"$cut":{"chars":30688,"head":"GO:0044700 single organism signaling; GO:0002694 regulation of leukocyte activation; GO:0035094 response to nicotine; GO:0048732 gland development; GO:0022414 reproductive process; GO:0098542 defense response to other organism; GO:0045634 regulation of melanocyte differentiation; GO:0030641 regulation of cellular pH; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0009607 response to biotic stimulus; GO:0030888 regulation of B cell proliferation; GO:0001558 regulation of cell growth; GO:0042110 T cell activation; GO:0032946 positive regulation of mononuclear cell proliferation; GO:0007160 cell-matrix adhesion; GO:0055065 metal ion homeostasis; GO:0008544 epidermis development; GO:0010830 regulation of myotube differentiation; GO:0034332 adherens junction organization; GO:0051147 regulation of muscle cell differentiation; GO:0043588 skin development; GO:0080090 regulation of primary metabolic process; GO:0050864 regulation of B cell activation; GO:2000134 negative regulation of G1/S transition of mitotic cell cycle; GO:0010506 regulation of autophagy; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0006810 transport; GO:0001656 metanephros development; GO:1902532 negative regulation of intracellular signal transduction; GO:0033689 negative regulation of osteoblast proliferation; GO:0051149 positive regulation of muscle cell differentiation; GO:0010721 negative regulation of cell development; GO:0060548 negative regulation of cell death; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0002009 morphogenesis of an epithelium; GO:2001239 regulation of extrinsic apoptotic signaling pathway in absence of ligand; GO:0044707 single-multicellular organism process; GO:0016310 phosphorylation; GO:0006885 regulation of pH; GO:0042303 molting cycle; GO:0009653 anatomical structure morphogenesis; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0009889 regulation of biosynthetic process; GO:0010959 regulation of metal ion transport; GO:0042100 B cell proliferation; GO:0061458 reproductive system development; GO:0032409 regulation of transporter activity; GO:0048878 chemical homeostasis; GO:0030902 hindbrain development; GO:0060562 epithelial tube morphogenesis; GO:0001822 kidney development; GO:0009416 response to light stimulus; GO:0042149 cellular response to glucose starvation; GO:0060284 regulation of cell development; GO:0048546 digestive tract morphogenesis; GO:0008283 cell proliferation; GO:0002376 immune system process; GO:0043496 regulation of protein homodimerization activity; GO:0010033 response to organic substance; GO:0042633 hair cycle; GO:0033033 negative regulation of myeloid cell apoptotic process; GO:0006974 cellular response to DNA damage stimulus; GO:0014911 positive regulation of smooth muscle cell migration; GO:0030336 negative regulation of cell migration; GO:0006955 immune response; GO:0043412 macromolecule modification; GO:0033059 cellular pigmentation; GO:0008284 positive regulation of cell proliferation; GO:2000045 regulation of G1/S transition of mitotic cell cycle; GO:0051093 negative regulation of developmental process; GO:0018209 peptidyl-serine modification; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0045216 cell-cell junction organization; GO:0006796 phosphate-containing compound metabolic process; GO:0001823 mesonephros development; GO:0009611 response to wounding; GO:0040013 negative regulation of locomotion; GO:0048729 tissue morphogenesis; GO:0016337 single organismal cell-cell adhesion; GO:0045930 negative regulation of mitotic cell cycle; GO:0007165 signal transduction; GO:0032990 cell part morphogenesis; GO:1902806 regulation of cell cycle G1/S phase transition; GO:0048858 cell projection morphogenesis; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0007045 cell-substrate adherens junction assembly; GO:0051726 regulation of cell cycle; GO:0032943 mononuclear cell proliferation; GO:0045926 negativ"}},"GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0019867 outer membrane; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0031965 nuclear membrane; GO:0070013 intracellular organelle lumen; GO:0043209 myelin sheath; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0031968 organelle outer membrane; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0044429 mitochondrial part; GO:0005635 nuclear envelope; GO:0046930 pore complex; GO:0005741 mitochondrial outer membrane; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0016021 integral component of membrane; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0044432 endoplasmic reticulum part; GO:0031975 envelope; GO:0043234 protein complex; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0003677 DNA binding; GO:0051434 BH3 domain binding; GO:0046982 protein heterodimerization activity; GO:0019903 protein phosphatase binding; GO:0031625 ubiquitin protein ligase binding; GO:0046983 protein dimerization activity; GO:0022803 passive transmembrane transporter activity; GO:0005515 protein binding; GO:0043565 sequence-specific DNA binding; GO:0098772 molecular function regulator; GO:0051721 protein phosphatase 2A binding; GO:0016248 channel inhibitor activity; GO:0015267 channel activity; GO:0002020 protease binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0070513 death domain binding; GO:0042802 identical protein binding; GO:0051400 BH domain binding; GO:0016247 channel regulator activity; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0019904 protein domain specific binding; GO:0019902 phosphatase binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0008134 transcription factor binding; GO:0019899 enzyme binding; GO:0022857 transmembrane transporter activity; GO:0005215 transporter activity; ","K02161","BCL2; apoptosis regulator Bcl-2","hsa05152 Tuberculosis - Homo sapiens (human); hsa05222 Small cell lung cancer - Homo sapiens (human); hsa05206 MicroRNAs in cancer - Homo sapiens (human); hsa05145 Toxoplasmosis - Homo sapiens (human); hsa04140 Autophagy - animal - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa04071 Sphingolipid signaling pathway - Homo sapiens (human); hsa04933 AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human); hsa05014 Amyotrophic lateral sclerosis (ALS) - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa01522 Endocrine resistance - Homo sapiens (human); hsa04340 Hedgehog signaling pathway - Homo sapiens (human); hsa05161 Hepatitis B - Homo sapiens (human); hsa05215 Prostate cancer - Homo sapiens (human); hsa04215 Apoptosis - multiple species - Homo sapiens (human); hsa01521 EGFR tyrosine kinase inhibitor resistance - Homo sapiens (human); hsa05210 Colorectal cancer - Homo sapiens (human); hsa04915 Estrogen signaling pathway - Homo sapiens (human); hsa04064 NF-kappa B signaling pathway - Homo sapiens (human); hsa04725 Cholinergic synapse - Homo sapiens (human); hsa04630 Jak-STAT signaling pathway - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); hsa04210 Apoptosis - Homo sapiens (human); hsa04722 Neurotrophin signaling pathway - Homo sapiens (human); hsa04217 Necroptosis - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human); hsa01524 Platinum drug resistance - Homo sapiens (human); hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human); hsa04066 HIF-1 signaling pathway - Homo sapiens (human); hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human); hsa05226 Gastric cancer - Homo sapiens (human); hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); hsa04928 Parathyroid hormone synthesis, secretion and action - Homo sapiens (human); ","IPR003093; ","\"Apoptosis regulator, Bcl-2 protein, BH4; \"\r"]
["P10515","Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT","DLAT",68.996,131.26,23.2,13,22,13,1.015,1.051,1.098,1.015,0.967,0.978,0.936,0.0702,"mitochondria\r","GO:0051188 cofactor biosynthetic process; GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0019216 regulation of lipid metabolic process; GO:0044237 cellular metabolic process; GO:0035384 thioester biosynthetic process; GO:0044272 sulfur compound biosynthetic process; GO:0006085 acetyl-CoA biosynthetic process; GO:0006006 glucose metabolic process; GO:0051196 regulation of coenzyme metabolic process; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0032787 monocarboxylic acid metabolic process; GO:0009108 coenzyme biosynthetic process; GO:0046487 glyoxylate metabolic process; GO:0006790 sulfur compound metabolic process; GO:0051193 regulation of cofactor metabolic process; GO:0072350 tricarboxylic acid metabolic process; GO:0051174 regulation of phosphorus metabolic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0071616 acyl-CoA biosynthetic process; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006081 cellular aldehyde metabolic process; GO:0006732 coenzyme metabolic process; GO:0006084 acetyl-CoA metabolic process; GO:0005975 carbohydrate metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0051186 cofactor metabolic process; GO:0010565 regulation of cellular ketone metabolic process; GO:0006101 citrate metabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0050789 regulation of biological process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0019222 regulation of metabolic process; GO:0030431 sleep; GO:0006082 organic acid metabolic process; GO:0042762 regulation of sulfur metabolic process; GO:0043436 oxoacid metabolic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0071704 organic substance metabolic process; GO:0006090 pyruvate metabolic process; GO:0009889 regulation of biosynthetic process; GO:0050812 regulation of acyl-CoA biosynthetic process; GO:0005996 monosaccharide metabolic process; GO:0009987 cellular process; GO:0044711 single-organism biosynthetic process; GO:0006099 tricarboxylic acid cycle; GO:0035383 thioester metabolic process; GO:0044238 primary metabolic process; GO:0045333 cellular respiration; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0006637 acyl-CoA metabolic process; GO:0019217 regulation of fatty acid metabolic process; GO:0006793 phosphorus metabolic process; GO:0009060 aerobic respiration; GO:0019752 carboxylic acid metabolic process; GO:0006086 acetyl-CoA biosynthetic process from pyruvate; GO:0065007 biological regulation; GO:0019318 hexose metabolic process; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0045254 pyruvate dehydrogenase complex; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0043209 myelin sheath; GO:0044464 cell part; GO:0005622 intracellular; GO:1990204 oxidoreductase complex; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0005967 mitochondrial pyruvate dehydrogenase complex; ","GO:0016417 S-acyltransferase activity; GO:0004742 dihydrolipoyllysine-residue acetyltransferase activity; GO:0016746 transferase activity, transferring acyl groups; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016418 S-acetyltransferase activity; GO:0005515 protein binding; GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups; GO:0030523 dihydrolipoamide S-acyltransferase activity; GO:0016740 transferase activity; GO:0016407 acetyltransferase activity; ","K00627","DLAT; pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) [EC:2.3.1.12]","hsa00620 Pyruvate metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00020 Citrate cycle (TCA cycle) - Homo sapiens (human); hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); ","IPR004167; IPR001078; IPR011053; IPR000089; IPR023213; ","\"E3-binding domain; 2-oxoacid dehydrogenase acyltransferase, catalytic domain; Single hybrid motif; Biotin/lipoyl attachment; Chloramphenicol acetyltransferase-like domain; \"\r"]
["P10599","Thioredoxin OS=Homo sapiens OX=9606 GN=TXN","TXN",11.737,31.363,51.4,7,17,7,0.912,0.953,0.981,1.042,1.064,1.053,1.11,0.00896,"extracellular\r","GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0051896 regulation of protein kinase B signaling; GO:0097659 nucleic acid-templated transcription; GO:1903533 regulation of protein targeting; GO:0090317 negative regulation of intracellular protein transport; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0051347 positive regulation of transferase activity; GO:0098869 cellular oxidant detoxification; GO:0032387 negative regulation of intracellular transport; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0051099 positive regulation of binding; GO:0033138 positive regulation of peptidyl-serine phosphorylation; GO:0046823 negative regulation of nucleocytoplasmic transport; GO:1901032 negative regulation of response to reactive oxygen species; GO:0051051 negative regulation of transport; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:0000302 response to reactive oxygen species; GO:0044281 small molecule metabolic process; GO:0000122 negative regulation of transcription from RNA polymerase II promoter; GO:0044763 single-organism cellular process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0043388 positive regulation of DNA binding; GO:1903506 regulation of nucleic acid-templated transcription; GO:0080135 regulation of cellular response to stress; GO:1903205 regulation of hydrogen peroxide-induced cell death; GO:0007267 cell-cell signaling; GO:0046825 regulation of protein export from nucleus; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:1903202 negative regulation of oxidative stress-induced cell death; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051223 regulation of protein transport; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0060548 negative regulation of cell death; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0045454 cell redox homeostasis; GO:1901700 response to oxygen-containing compound; GO:0044267 cellular protein metabolic process; GO:0033158 regulation of protein import into nucleus, translocation; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0030091 protein repair; GO:0048519 negative regulation of biological process; GO:0060341 regulation of cellular localization; GO:0045892 negative regulation of transcription, DNA-templated; GO:1990748 cellular detoxification; GO:0032147 activation of protein kinase activity; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0032880 regulation of protein localization; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0009966 regulation of signal transduction; GO:1902531 regulation of intracellular signal transduction; GO:0006950 response to stress; GO:0051224 negative regulation of protein transport; GO:0033135 regulation of peptidyl-serine phosphorylation; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0008283 cell proliferation; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:1900408 negative regulation of cellular response to oxidative stress; GO:0009890 negative regulation of biosynthetic process; GO:0051247 positive regulation of protein metabolic process; GO:0046822 regulation of nucleocytoplasmic transport; GO:0031325 positive regulation of cellular metabolic process; GO:0006928 movement of cell or subcellular component; GO:1902882 regulation of response to oxidative stress; GO:0048584 positive regulation of response to stimulus; GO:1903827 regulation of cellular protein localization; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0051253 negative regulation of RNA metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0042306 regulation of protein import into nucleus; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0006979 response to oxidative stress; GO:0009314 response to radiation; GO:0033674 positive regulation of kinase activity; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0010468 regulation of gene expression; GO:1903828 negative regulation of cellular protein localization; GO:0045937 positive regulation of phosphate metabolic process; GO:0031326 regulation of cellular biosynthetic process; GO:0055114 oxidation-reduction process; GO:0009636 response to toxic substance; GO:0051098 regulation of binding; GO:0019725 cellular homeostasis; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0032386 regulation of intracellular transport; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0016070 RNA metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:1902883 negative regulation of response to oxidative stress; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:1902679 negative regulation of RNA biosynthetic process; GO:1900180 regulation of protein localization to nucleus; GO:1903206 negative regulation of hydrogen peroxide-induced cell death; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0098754 detoxification; GO:0043549 regulation of kinase activity; GO:0045859 regulation of protein kinase activity; GO:0006725 cellular aromatic compound metabolic process; GO:0015949 nucleobase-containing small molecule interconversion; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:1903201 regulation of oxidative stress-induced cell death; GO:0031324 negative regulation of cellular metabolic process; GO:1904589 regulation of protein import; GO:0050896 response to stimulus; GO:0051101 regulation of DNA binding; GO:0046826 negative regulation of protein export from nucleus; GO:0070201 regulation of establishment of protein localization; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0023056 positive regulation of signaling; GO:0006662 glycerol ether metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0010647 positive regulation of cell communication; GO:0009059 macromolecule biosynthetic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0033157 regulation of intracellular protein transport; GO:0009987 cellular process; GO:0032148 activation of protein kinase B activity; GO:0051897 positive regulation of protein kinase B signaling; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0051049 regulation of transport; GO:0001932 regulation of protein phosphorylation; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0018904 ether metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0031401 positive regulation of protein modification process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0001934 positive regulation of protein phosphorylation; GO:0045860 positive regulation of protein kinase activity; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0043085 positive regulation of catalytic activity; GO:1900407 regulation of cellular response to oxidative stress; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0051246 regulation of protein metabolic process; GO:0010467 gene expression; GO:1904950 negative regulation of establishment of protein localization; GO:0031327 negative regulation of cellular biosynthetic process; GO:0009967 positive regulation of signal transduction; GO:1901031 regulation of response to reactive oxygen species; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0015035 protein disulfide oxidoreductase activity; GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:0003723 RNA binding; GO:0004791 thioredoxin-disulfide reductase activity; GO:0047134 protein-disulfide reductase activity; GO:0016209 antioxidant activity; GO:0005515 protein binding; GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor; GO:0016491 oxidoreductase activity; GO:0015036 disulfide oxidoreductase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0016667 oxidoreductase activity, acting on a sulfur group of donors; GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor; GO:0015037 peptide disulfide oxidoreductase activity; ","K03671","trxA; thioredoxin 1","hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human); hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human); ","IPR013766; IPR012336; ","Thioredoxin domain; Thioredoxin-like fold; \r"]
["P10606","Cytochrome c oxidase subunit 5B, mitochondrial OS=Homo sapiens OX=9606 GN=COX5B","COX5B",13.696,12.677,30.2,5,8,5,1.023,1.078,1.001,0.984,0.951,1.039,0.959,0.28,"mitochondria\r","GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0006123 mitochondrial electron transport, cytochrome c to oxygen; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0006839 mitochondrial transport; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0009163 nucleoside biosynthetic process; GO:0046129 purine ribonucleoside biosynthetic process; GO:0009156 ribonucleoside monophosphate biosynthetic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0046390 ribose phosphate biosynthetic process; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:1901137 carbohydrate derivative biosynthetic process; GO:0006091 generation of precursor metabolites and energy; GO:0006753 nucleoside phosphate metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0009145 purine nucleoside triphosphate biosynthetic process; GO:0044765 single-organism transport; GO:0018130 heterocycle biosynthetic process; GO:0009206 purine ribonucleoside triphosphate biosynthetic process; GO:0098655 cation transmembrane transport; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0006754 ATP biosynthetic process; GO:0006119 oxidative phosphorylation; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0015985 energy coupled proton transport, down electrochemical gradient; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0032501 multicellular organismal process; GO:0009168 purine ribonucleoside monophosphate biosynthetic process; GO:1902582 single-organism intracellular transport; GO:0042451 purine nucleoside biosynthetic process; GO:0090407 organophosphate biosynthetic process; GO:0006810 transport; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0072522 purine-containing compound biosynthetic process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0015986 ATP synthesis coupled proton transport; GO:0022900 electron transport chain; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0006164 purine nucleotide biosynthetic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0098662 inorganic cation transmembrane transport; GO:0009201 ribonucleoside triphosphate biosynthetic process; GO:0046907 intracellular transport; GO:0044707 single-multicellular organism process; GO:0016310 phosphorylation; GO:0009165 nucleotide biosynthetic process; GO:0034220 ion transmembrane transport; GO:0042776 mitochondrial ATP synthesis coupled proton transport; GO:0006725 cellular aromatic compound metabolic process; GO:0042773 ATP synthesis coupled electron transport; GO:0009259 ribonucleotide metabolic process; GO:0009142 nucleoside triphosphate biosynthetic process; GO:0022904 respiratory electron transport chain; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006812 cation transport; GO:0006139 nucleobase-containing compound metabolic process; GO:1990542 mitochondrial transmembrane transport; GO:1902600 hydrogen ion transmembrane transport; GO:1901135 carbohydrate derivative metabolic process; GO:1902580 single-organism cellular localization; GO:0034641 cellular nitrogen compound metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009119 ribonucleoside metabolic process; GO:0009987 cellular process; GO:0046034 ATP metabolic process; GO:0009124 nucleoside monophosphate biosynthetic process; GO:0044711 single-organism biosynthetic process; GO:0098660 inorganic ion transmembrane transport; GO:0009127 purine nucleoside monophosphate biosynthetic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0042455 ribonucleoside biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0045333 cellular respiration; GO:0044249 cellular biosynthetic process; GO:0006818 hydrogen transport; GO:0015992 proton transport; GO:0006163 purine nucleotide metabolic process; GO:0051641 cellular localization; GO:0055085 transmembrane transport; GO:0007585 respiratory gaseous exchange; GO:0046128 purine ribonucleoside metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0009152 purine ribonucleotide biosynthetic process; GO:0006793 phosphorus metabolic process; GO:1901659 glycosyl compound biosynthetic process; GO:0006811 ion transport; GO:0009260 ribonucleotide biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0051179 localization; GO:0015672 monovalent inorganic cation transport; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0019866 organelle inner membrane; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0098803 respiratory chain complex; GO:0005751 mitochondrial respiratory chain complex IV; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0070069 cytochrome complex; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005746 mitochondrial respiratory chain; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0045277 respiratory chain complex IV; GO:0031975 envelope; GO:0043234 protein complex; GO:0070469 respiratory chain; GO:0043230 extracellular organelle; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0015075 ion transmembrane transporter activity; GO:0043167 ion binding; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0015077 monovalent inorganic cation transmembrane transporter activity; GO:0016676 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor; GO:0016675 oxidoreductase activity, acting on a heme group of donors; GO:0015078 hydrogen ion transmembrane transporter activity; GO:0015002 heme-copper terminal oxidase activity; GO:0016491 oxidoreductase activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0009055 electron carrier activity; GO:0004129 cytochrome-c oxidase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0022890 inorganic cation transmembrane transporter activity; GO:0008324 cation transmembrane transporter activity; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; ","K02265","COX5B; cytochrome c oxidase subunit 5b","hsa04260 Cardiac muscle contraction - Homo sapiens (human); hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); "]
["P10619","Lysosomal protective protein OS=Homo sapiens OX=9606 GN=CTSA","CTSA",54.465,24.009,11.7,5,8,5,0.948,0.848,0.906,1.079,1.097,1.071,1.202,0.00508,"extracellular\r","GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0006643 membrane lipid metabolic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0044093 positive regulation of molecular function; GO:0006665 sphingolipid metabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0006629 lipid metabolic process; GO:0002443 leukocyte mediated immunity; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0002446 neutrophil mediated immunity; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0006664 glycolipid metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0010506 regulation of autophagy; GO:0002444 myeloid leukocyte mediated immunity; GO:1904715 negative regulation of chaperone-mediated autophagy; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0050789 regulation of biological process; GO:0050790 regulation of catalytic activity; GO:0032940 secretion by cell; GO:0030163 protein catabolic process; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0010507 negative regulation of autophagy; GO:0043299 leukocyte degranulation; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:1903509 liposaccharide metabolic process; GO:0044257 cellular protein catabolic process; GO:0002283 neutrophil activation involved in immune response; GO:0042177 negative regulation of protein catabolic process; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0006687 glycosphingolipid metabolic process; GO:0044267 cellular protein metabolic process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0006886 intracellular protein transport; GO:0044248 cellular catabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0009895 negative regulation of catabolic process; GO:0006508 proteolysis; GO:0042176 regulation of protein catabolic process; GO:0036230 granulocyte activation; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0044265 cellular macromolecule catabolic process; GO:0016192 vesicle-mediated transport; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:1904714 regulation of chaperone-mediated autophagy; GO:0043312 neutrophil degranulation; GO:0009892 negative regulation of metabolic process; GO:0002263 cell activation involved in immune response; GO:0051641 cellular localization; GO:0043085 positive regulation of catalytic activity; GO:0045184 establishment of protein localization; GO:0002366 leukocyte activation involved in immune response; GO:0031330 negative regulation of cellular catabolic process; GO:0070727 cellular macromolecule localization; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:0051246 regulation of protein metabolic process; GO:0009057 macromolecule catabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0001775 cell activation; GO:0031647 regulation of protein stability; GO:0051179 localization; GO:0006955 immune response; GO:0009056 catabolic process; GO:0006887 exocytosis; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0043202 lysosomal lumen; GO:0042582 azurophil granule; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0004180 carboxypeptidase activity; GO:0008233 peptidase activity; GO:0008238 exopeptidase activity; GO:0008236 serine-type peptidase activity; GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds; GO:0016787 hydrolase activity; GO:0098772 molecular function regulator; GO:0070008 serine-type exopeptidase activity; GO:0030234 enzyme regulator activity; GO:0003824 catalytic activity; GO:0017171 serine hydrolase activity; GO:0016798 hydrolase activity, acting on glycosyl bonds; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0004308 exo-alpha-sialidase activity; GO:0004185 serine-type carboxypeptidase activity; GO:0008047 enzyme activator activity; GO:0016997 alpha-sialidase activity; ","K13289","CTSA; cathepsin A (carboxypeptidase C) [EC:3.4.16.5]","hsa04142 Lysosome - Homo sapiens (human); hsa04614 Renin-angiotensin system - Homo sapiens (human); ","IPR029058; ","Alpha/Beta hydrolase fold; \r"]
["P10620","Microsomal glutathione S-transferase 1 OS=Homo sapiens OX=9606 GN=MGST1","MGST1",17.598,26.67,9,2,2,2,1.312,1.287,1.336,0.709,0.743,0.661,0.537,6.15e-05,"cyto_nucl\r","GO:0044085 cellular component biogenesis; GO:0045321 leukocyte activation; GO:0006518 peptide metabolic process; GO:0033194 response to hydroperoxide; GO:0022414 reproductive process; GO:0048869 cellular developmental process; GO:0008584 male gonad development; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0044272 sulfur compound biosynthetic process; GO:0051234 establishment of localization; GO:0009607 response to biotic stimulus; GO:0009605 response to external stimulus; GO:1901685 glutathione derivative metabolic process; GO:0008152 metabolic process; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0044702 single organism reproductive process; GO:0006979 response to oxidative stress; GO:0009719 response to endogenous stimulus; GO:0006749 glutathione metabolic process; GO:0006982 response to lipid hydroperoxide; GO:0033327 Leydig cell differentiation; GO:0098869 cellular oxidant detoxification; GO:0034599 cellular response to oxidative stress; GO:0070887 cellular response to chemical stimulus; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0032502 developmental process; GO:0006790 sulfur compound metabolic process; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0003006 developmental process involved in reproduction; GO:0071822 protein complex subunit organization; GO:0055114 oxidation-reduction process; GO:0002237 response to molecule of bacterial origin; GO:0002446 neutrophil mediated immunity; GO:0009636 response to toxic substance; GO:0044763 single-organism cellular process; GO:0048608 reproductive structure development; GO:0043603 cellular amide metabolic process; GO:0032501 multicellular organismal process; GO:0002444 myeloid leukocyte mediated immunity; GO:0051704 multi-organism process; GO:0006810 transport; GO:0010243 response to organonitrogen compound; GO:0048513 animal organ development; GO:0042221 response to chemical; GO:0032940 secretion by cell; GO:0044710 single-organism metabolic process; GO:1901698 response to nitrogen compound; GO:0043299 leukocyte degranulation; GO:0070271 protein complex biogenesis; GO:0048856 anatomical structure development; GO:0098754 detoxification; GO:0071466 cellular response to xenobiotic stimulus; GO:0000003 reproduction; GO:0016043 cellular component organization; GO:0033554 cellular response to stress; GO:0044707 single-multicellular organism process; GO:0002283 neutrophil activation involved in immune response; GO:0051260 protein homooligomerization; GO:0002252 immune effector process; GO:0046661 male sex differentiation; GO:1901700 response to oxygen-containing compound; GO:0008406 gonad development; GO:0043207 response to external biotic stimulus; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0051259 protein oligomerization; GO:0071704 organic substance metabolic process; GO:0042493 response to drug; GO:0033993 response to lipid; GO:0030154 cell differentiation; GO:1990748 cellular detoxification; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0006805 xenobiotic metabolic process; GO:0009410 response to xenobiotic stimulus; GO:0006575 cellular modified amino acid metabolic process; GO:0071449 cellular response to lipid hydroperoxide; GO:0007548 sex differentiation; GO:0034641 cellular nitrogen compound metabolic process; GO:0036230 granulocyte activation; GO:0007275 multicellular organism development; GO:0061458 reproductive system development; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0009617 response to bacterium; GO:0045137 development of primary sexual characteristics; GO:0071447 cellular response to hydroperoxide; GO:0070206 protein trimerization; GO:0044711 single-organism biosynthetic process; GO:0006950 response to stress; GO:0032496 response to lipopolysaccharide; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0006807 nitrogen compound metabolic process; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0043312 neutrophil degranulation; GO:1901576 organic substance biosynthetic process; GO:0002263 cell activation involved in immune response; GO:0044249 cellular biosynthetic process; GO:1901687 glutathione derivative biosynthetic process; GO:0070207 protein homotrimerization; GO:0043933 macromolecular complex subunit organization; GO:0002366 leukocyte activation involved in immune response; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:1901701 cellular response to oxygen-containing compound; GO:0044767 single-organism developmental process; GO:0001775 cell activation; GO:0046546 development of primary male sexual characteristics; GO:0051179 localization; GO:0006955 immune response; GO:0071840 cellular component organization or biogenesis; GO:0006887 exocytosis; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0019867 outer membrane; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044438 microbody part; GO:0005623 cell; GO:0044422 organelle part; GO:0005778 peroxisomal membrane; GO:0005765 lysosomal membrane; GO:0005622 intracellular; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0005789 endoplasmic reticulum membrane; GO:0045177 apical part of cell; GO:0000323 lytic vacuole; GO:0044439 peroxisomal part; GO:0031967 organelle envelope; GO:0035577 azurophil granule membrane; GO:0012506 vesicle membrane; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0042582 azurophil granule; GO:0043231 intracellular membrane-bounded organelle; GO:0030667 secretory granule membrane; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0031975 envelope; GO:0005773 vacuole; GO:0031966 mitochondrial membrane; GO:0005783 endoplasmic reticulum; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005740 mitochondrial envelope; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0042579 microbody; GO:0019866 organelle inner membrane; GO:0031968 organelle outer membrane; GO:0030141 secretory granule; GO:0031903 microbody membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0044429 mitochondrial part; GO:0098588 bounding membrane of organelle; GO:0005777 peroxisome; GO:0005741 mitochondrial outer membrane; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0016021 integral component of membrane; GO:0098852 lytic vacuole membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0005634 nucleus; GO:0044432 endoplasmic reticulum part; GO:0005774 vacuolar membrane; GO:0044444 cytoplasmic part; ","GO:0004602 glutathione peroxidase activity; GO:0046983 protein dimerization activity; GO:0043167 ion binding; GO:0016209 antioxidant activity; GO:0005515 protein binding; GO:0033218 amide binding; GO:0043295 glutathione binding; GO:1900750 oligopeptide binding; GO:1901681 sulfur compound binding; GO:0016491 oxidoreductase activity; GO:0004364 glutathione transferase activity; GO:0042802 identical protein binding; GO:0072341 modified amino acid binding; GO:0003824 catalytic activity; GO:0042277 peptide binding; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups; GO:0043168 anion binding; GO:0004601 peroxidase activity; GO:0016740 transferase activity; GO:0016684 oxidoreductase activity, acting on peroxide as acceptor; ","K00799","GST; glutathione S-transferase [EC:2.5.1.18]","hsa01524 Platinum drug resistance - Homo sapiens (human); hsa00480 Glutathione metabolism - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa05204 Chemical carcinogenesis - Homo sapiens (human); hsa00980 Metabolism of xenobiotics by cytochrome P450 - Homo sapiens (human); hsa05225 Hepatocellular carcinoma - Homo sapiens (human); hsa00983 Drug metabolism - other enzymes - Homo sapiens (human); hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human); hsa00982 Drug metabolism - cytochrome P450 - Homo sapiens (human); hsa05215 Prostate cancer - Homo sapiens (human); ","IPR023352; ","Membrane associated eicosanoid/glutathione metabolism-like domain; \r"]
["P10643","Complement component C7 OS=Homo sapiens OX=9606 GN=C7","C7",93.517,101.62,14.1,11,15,10,1.031,0.979,1.021,1.004,0.975,0.994,0.981,0.349,"extracellular\r","GO:0065008 regulation of biological quality; GO:0016064 immunoglobulin mediated immune response; GO:0044699 single-organism process; GO:0030004 cellular monovalent inorganic cation homeostasis; GO:0031347 regulation of defense response; GO:0006956 complement activation; GO:0008152 metabolic process; GO:0002250 adaptive immune response; GO:0055065 metal ion homeostasis; GO:0006958 complement activation, classical pathway; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0002697 regulation of immune effector process; GO:0055078 sodium ion homeostasis; GO:0010468 regulation of gene expression; GO:0002443 leukocyte mediated immunity; GO:0050801 ion homeostasis; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0098771 inorganic ion homeostasis; GO:0019725 cellular homeostasis; GO:0006883 cellular sodium ion homeostasis; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0050776 regulation of immune response; GO:0050789 regulation of biological process; GO:0048583 regulation of response to stimulus; GO:0019222 regulation of metabolic process; GO:0002682 regulation of immune system process; GO:0006952 defense response; GO:1903317 regulation of protein maturation; GO:0030449 regulation of complement activation; GO:2000257 regulation of protein activation cascade; GO:0019835 cytolysis; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0030003 cellular cation homeostasis; GO:0002920 regulation of humoral immune response; GO:0002673 regulation of acute inflammatory response; GO:0006959 humoral immune response; GO:0080134 regulation of response to stress; GO:0050896 response to stimulus; GO:0055082 cellular chemical homeostasis; GO:0045087 innate immune response; GO:0071704 organic substance metabolic process; GO:0019724 B cell mediated immunity; GO:0042592 homeostatic process; GO:0055080 cation homeostasis; GO:0002449 lymphocyte mediated immunity; GO:0050778 positive regulation of immune response; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0002253 activation of immune response; GO:0055067 monovalent inorganic cation homeostasis; GO:0006950 response to stress; GO:0002376 immune system process; GO:0072376 protein activation cascade; GO:0032101 regulation of response to external stimulus; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0006873 cellular ion homeostasis; GO:0006957 complement activation, alternative pathway; GO:0051246 regulation of protein metabolic process; GO:0002684 positive regulation of immune system process; GO:0050727 regulation of inflammatory response; GO:0070613 regulation of protein processing; GO:0006875 cellular metal ion homeostasis; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0048584 positive regulation of response to stimulus; GO:0006955 immune response; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0031226 intrinsic component of plasma membrane; GO:0044421 extracellular region part; GO:0098796 membrane protein complex; GO:0071944 cell periphery; GO:0046930 pore complex; GO:0098797 plasma membrane protein complex; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0044459 plasma membrane part; GO:0044464 cell part; GO:0044425 membrane part; GO:1903561 extracellular vesicle; GO:0005579 membrane attack complex; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0005515 protein binding; GO:0005488 binding; ","K03996","C7; complement component 7","hsa05322 Systemic lupus erythematosus - Homo sapiens (human); hsa04610 Complement and coagulation cascades - Homo sapiens (human); hsa05020 Prion diseases - Homo sapiens (human); ","IPR020864; IPR000436; IPR003884; ","Membrane attack complex component/perforin (MACPF) domain; Sushi/SCR/CCP domain; Factor I / membrane attack complex; \r"]
["P10644","cAMP-dependent protein kinase type I-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR1A","PRKAR1A",42.981,96.982,36.5,12,17,12,1.009,0.98,1.006,0.975,1.019,1.011,1.003,0.854,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0002694 regulation of leukocyte activation; GO:0050672 negative regulation of lymphocyte proliferation; GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0032944 regulation of mononuclear cell proliferation; GO:0032270 positive regulation of cellular protein metabolic process; GO:0022414 reproductive process; GO:0032989 cellular component morphogenesis; GO:0010564 regulation of cell cycle process; GO:0008285 negative regulation of cell proliferation; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0030036 actin cytoskeleton organization; GO:0007507 heart development; GO:0070664 negative regulation of leukocyte proliferation; GO:0044702 single organism reproductive process; GO:0044093 positive regulation of molecular function; GO:0051784 negative regulation of nuclear division; GO:0009719 response to endogenous stimulus; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0051347 positive regulation of transferase activity; GO:0055017 cardiac muscle tissue growth; GO:0009790 embryo development; GO:1901652 response to peptide; GO:0048598 embryonic morphogenesis; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:0060537 muscle tissue development; GO:1903038 negative regulation of leukocyte cell-cell adhesion; GO:0044763 single-organism cellular process; GO:0001707 mesoderm formation; GO:0046006 regulation of activated T cell proliferation; GO:0050670 regulation of lymphocyte proliferation; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0007498 mesoderm development; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0010243 response to organonitrogen compound; GO:0010948 negative regulation of cell cycle process; GO:0055002 striated muscle cell development; GO:0030104 water homeostasis; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:2000242 negative regulation of reproductive process; GO:1901698 response to nitrogen compound; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051447 negative regulation of meiotic cell cycle; GO:0002682 regulation of immune system process; GO:0007143 female meiotic division; GO:0050817 coagulation; GO:0097435 supramolecular fiber organization; GO:0060419 heart growth; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0000003 reproduction; GO:0055001 muscle cell development; GO:0072359 circulatory system development; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0007162 negative regulation of cell adhesion; GO:0042127 regulation of cell proliferation; GO:0031399 regulation of protein modification process; GO:1901700 response to oxygen-containing compound; GO:0022408 negative regulation of cell-cell adhesion; GO:0045835 negative regulation of meiotic nuclear division; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0014855 striated muscle cell proliferation; GO:0035265 organ growth; GO:0050866 negative regulation of cell activation; GO:0009653 anatomical structure morphogenesis; GO:0032147 activation of protein kinase activity; GO:0030239 myofibril assembly; GO:0009889 regulation of biosynthetic process; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:0051338 regulation of transferase activity; GO:0061061 muscle structure development; GO:0051171 regulation of nitrogen compound metabolic process; GO:0001933 negative regulation of protein phosphorylation; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0034199 activation of protein kinase A activity; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0048878 chemical homeostasis; GO:0006950 response to stress; GO:0048731 system development; GO:0003014 renal system process; GO:0010927 cellular component assembly involved in morphogenesis; GO:0008283 cell proliferation; GO:0010033 response to organic substance; GO:0009892 negative regulation of metabolic process; GO:0030155 regulation of cell adhesion; GO:0051247 positive regulation of protein metabolic process; GO:0006996 organelle organization; GO:0050891 multicellular organismal water homeostasis; GO:0030029 actin filament-based process; GO:0031325 positive regulation of cellular metabolic process; GO:0000280 nuclear division; GO:0033762 response to glucagon; GO:0048589 developmental growth; GO:0040007 growth; GO:0045936 negative regulation of phosphate metabolic process; GO:0051445 regulation of meiotic cell cycle; GO:0050863 regulation of T cell activation; GO:0048869 cellular developmental process; GO:0051129 negative regulation of cellular component organization; GO:0044699 single-organism process; GO:0042130 negative regulation of T cell proliferation; GO:0051249 regulation of lymphocyte activation; GO:0031400 negative regulation of protein modification process; GO:0048871 multicellular organismal homeostasis; GO:0009611 response to wounding; GO:2001141 regulation of RNA biosynthetic process; GO:0048729 tissue morphogenesis; GO:0007165 signal transduction; GO:0051783 regulation of nuclear division; GO:0071901 negative regulation of protein serine/threonine kinase activity; GO:0007154 cell communication; GO:1901653 cellular response to peptide; GO:0022607 cellular component assembly; GO:0009893 positive regulation of metabolic process; GO:0033673 negative regulation of kinase activity; GO:0070663 regulation of leukocyte proliferation; GO:0033674 positive regulation of kinase activity; GO:0002695 negative regulation of leukocyte activation; GO:0051726 regulation of cell cycle; GO:0070887 cellular response to chemical stimulus; GO:0003091 renal water homeostasis; GO:0032502 developmental process; GO:0031032 actomyosin structure organization; GO:0010468 regulation of gene expression; GO:0009888 tissue development; GO:0045937 positive regulation of phosphate metabolic process; GO:0031326 regulation of cellular biosynthetic process; GO:0001704 formation of primary germ layer; GO:0048522 positive regulation of cellular process; GO:0051321 meiotic cell cycle; GO:0051348 negative regulation of transferase activity; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002683 negative regulation of immune system process; GO:0071417 cellular response to organonitrogen compound; GO:1902589 single-organism organelle organization; GO:2000480 negative regulation of cAMP-dependent protein kinase activity; GO:0010639 negative regulation of organelle organization; GO:2000241 regulation of reproductive process; GO:0045214 sarcomere organization; GO:0050865 regulation of cell activation; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0042221 response to chemical; GO:0043434 response to peptide hormone; GO:1901699 cellular response to nitrogen compound; GO:0032870 cellular response to hormone stimulus; GO:0006469 negative regulation of protein kinase activity; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0050868 negative regulation of T cell activation; GO:0048856 anatomical structure development; GO:0043549 regulation of kinase activity; GO:0014706 striated muscle tissue development; GO:0045859 regulation of protein kinase activity; GO:0016043 cellular component organization; GO:0045786 negative regulation of cell cycle; GO:1903046 meiotic cell cycle process; GO:0048738 cardiac muscle tissue development; GO:0051250 negative regulation of lymphocyte activation; GO:0060255 regulation of macromolecule metabolic process; GO:0048285 organelle fission; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0071310 cellular response to organic substance; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0007599 hemostasis; GO:0007369 gastrulation; GO:0071377 cellular response to glucagon stimulus; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:0070925 organelle assembly; GO:0042326 negative regulation of phosphorylation; GO:0071375 cellular response to peptide hormone stimulus; GO:0009987 cellular process; GO:0051146 striated muscle cell differentiation; GO:0046007 negative regulation of activated T cell proliferation; GO:0006355 regulation of transcription, DNA-templated; GO:0050878 regulation of body fluid levels; GO:0003008 system process; GO:0035556 intracellular signal transduction; GO:0001932 regulation of protein phosphorylation; GO:0060038 cardiac muscle cell proliferation; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0033043 regulation of organelle organization; GO:0031401 positive regulation of protein modification process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0042129 regulation of T cell proliferation; GO:0032945 negative regulation of mononuclear cell proliferation; GO:0001934 positive regulation of protein phosphorylation; GO:0045860 positive regulation of protein kinase activity; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0022407 regulation of cell-cell adhesion; GO:0043085 positive regulation of catalytic activity; GO:1901701 cellular response to oxygen-containing compound; GO:0048332 mesoderm morphogenesis; GO:0040020 regulation of meiotic nuclear division; GO:0042060 wound healing; GO:2000479 regulation of cAMP-dependent protein kinase activity; GO:0071495 cellular response to endogenous stimulus; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0010563 negative regulation of phosphorus metabolic process; GO:0042692 muscle cell differentiation; GO:0051248 negative regulation of protein metabolic process; GO:0007126 meiotic nuclear division; GO:0022402 cell cycle process; GO:0051128 regulation of cellular component organization; GO:0033002 muscle cell proliferation; GO:0009725 response to hormone; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0061695 transferase complex, transferring phosphorus-containing groups; GO:0098857 membrane microdomain; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:1902911 protein kinase complex; GO:0044422 organelle part; GO:1902494 catalytic complex; GO:0098590 plasma membrane region; GO:0044441 ciliary part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0098589 membrane region; GO:0045121 membrane raft; GO:0097546 ciliary base; GO:0005929 cilium; GO:0031588 nucleotide-activated protein kinase complex; GO:0042995 cell projection; GO:0031594 neuromuscular junction; GO:1990234 transferase complex; GO:0044463 cell projection part; GO:0005829 cytosol; GO:0045202 synapse; GO:0005886 plasma membrane; GO:0005952 cAMP-dependent protein kinase complex; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0044853 plasma membrane raft; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0030291 protein serine/threonine kinase inhibitor activity; GO:0051018 protein kinase A binding; GO:1901265 nucleoside phosphate binding; GO:0031625 ubiquitin protein ligase binding; GO:0019901 protein kinase binding; GO:0004860 protein kinase inhibitor activity; GO:0005515 protein binding; GO:0019207 kinase regulator activity; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0004862 cAMP-dependent protein kinase inhibitor activity; GO:0008603 cAMP-dependent protein kinase regulator activity; GO:0017076 purine nucleotide binding; GO:0030552 cAMP binding; GO:0030551 cyclic nucleotide binding; GO:0043167 ion binding; GO:0019887 protein kinase regulator activity; GO:0000166 nucleotide binding; GO:0019900 kinase binding; GO:0097367 carbohydrate derivative binding; GO:0030234 enzyme regulator activity; GO:0019210 kinase inhibitor activity; GO:0032555 purine ribonucleotide binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0034236 protein kinase A catalytic subunit binding; GO:0019899 enzyme binding; GO:0036094 small molecule binding; ","K04739","PRKAR; cAMP-dependent protein kinase regulator","hsa04910 Insulin signaling pathway - Homo sapiens (human); ","IPR000595; IPR003117; IPR018490; IPR014710; ","\"Cyclic nucleotide-binding domain; cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain; Cyclic nucleotide-binding-like; RmlC-like jelly roll fold; \"\r"]
["P10768","S-formylglutathione hydrolase OS=Homo sapiens OX=9606 GN=ESD","ESD",31.462,88.328,40.8,8,11,8,0.999,1.014,1.036,1.018,0.972,1.021,0.988,0.543,"cytoplasm\r","GO:0006790 sulfur compound metabolic process; GO:0044711 single-organism biosynthetic process; GO:0044712 single-organism catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:0006081 cellular aldehyde metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044282 small molecule catabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:1901576 organic substance biosynthetic process; GO:0044237 cellular metabolic process; GO:0044272 sulfur compound biosynthetic process; GO:0044249 cellular biosynthetic process; GO:1901687 glutathione derivative biosynthetic process; GO:0071704 organic substance metabolic process; GO:1901575 organic substance catabolic process; GO:1901685 glutathione derivative metabolic process; GO:0008152 metabolic process; GO:0046185 aldehyde catabolic process; GO:0044710 single-organism metabolic process; GO:0044248 cellular catabolic process; GO:0046294 formaldehyde catabolic process; GO:0009056 catabolic process; GO:0009987 cellular process; GO:0046292 formaldehyde metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0097708 intracellular vesicle; GO:0005788 endoplasmic reticulum lumen; GO:0043229 intracellular organelle; GO:0005783 endoplasmic reticulum; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0070013 intracellular organelle lumen; GO:0044432 endoplasmic reticulum part; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0047374 methylumbelliferyl-acetate deacetylase activity; GO:0042802 identical protein binding; GO:0052689 carboxylic ester hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0018738 S-formylglutathione hydrolase activity; GO:0016788 hydrolase activity, acting on ester bonds; GO:0019213 deacetylase activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0016790 thiolester hydrolase activity; ","K01070","frmB; S-formylglutathione hydrolase [EC:3.1.2.12]","hsa01200 Carbon metabolism - Homo sapiens (human); ","IPR029058; ","Alpha/Beta hydrolase fold; \r"]
["P10809","60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1","HSPD1",61.054,228.49,45.7,23,48,23,0.936,0.953,1.037,1.064,1.054,1.02,1.072,0.106,"mitochondria\r",{"$cut":{"chars":17512,"head":"GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0002694 regulation of leukocyte activation; GO:0009593 detection of chemical stimulus; GO:0010941 regulation of cell death; GO:0032680 regulation of tumor necrosis factor production; GO:0043523 regulation of neuron apoptotic process; GO:0046683 response to organophosphorus; GO:0031347 regulation of defense response; GO:0044237 cellular metabolic process; GO:0009607 response to biotic stimulus; GO:0042110 T cell activation; GO:0008152 metabolic process; GO:0065003 macromolecular complex assembly; GO:0044093 positive regulation of molecular function; GO:1904469 positive regulation of tumor necrosis factor secretion; GO:0002367 cytokine production involved in immune response; GO:0002709 regulation of T cell mediated immunity; GO:0052548 regulation of endopeptidase activity; GO:0051716 cellular response to stimulus; GO:0045190 isotype switching; GO:0010950 positive regulation of endopeptidase activity; GO:0060359 response to ammonium ion; GO:0050729 positive regulation of inflammatory response; GO:0080090 regulation of primary metabolic process; GO:0071806 protein transmembrane transport; GO:0002842 positive regulation of T cell mediated immune response to tumor cell; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0002520 immune system development; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0010243 response to organonitrogen compound; GO:0014823 response to activity; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0002381 immunoglobulin production involved in immunoglobulin mediated immune response; GO:0044260 cellular macromolecule metabolic process; GO:0051223 regulation of protein transport; GO:0072655 establishment of protein localization to mitochondrion; GO:0060548 negative regulation of cell death; GO:0002755 MyD88-dependent toll-like receptor signaling pathway; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0044707 single-multicellular organism process; GO:0002839 positive regulation of immune response to tumor cell; GO:2001056 positive regulation of cysteine-type endopeptidase activity; GO:0016445 somatic diversification of immunoglobulins; GO:0006259 DNA metabolic process; GO:0001819 positive regulation of cytokine production; GO:1901700 response to oxygen-containing compound; GO:0048519 negative regulation of biological process; GO:2000778 positive regulation of interleukin-6 secretion; GO:0019724 B cell mediated immunity; GO:0042493 response to drug; GO:0050867 positive regulation of cell activation; GO:0002208 somatic diversification of immunoglobulins involved in immune response; GO:0043524 negative regulation of neuron apoptotic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0051345 positive regulation of hydrolase activity; GO:0009889 regulation of biosynthetic process; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:0070482 response to oxygen levels; GO:1902580 single-organism cellular localization; GO:0042100 B cell proliferation; GO:2000378 negative regulation of reactive oxygen species metabolic process; GO:0034613 cellular protein localization; GO:0002449 lymphocyte mediated immunity; GO:0050778 positive regulation of immune response; GO:1901215 negative regulation of neuron death; GO:0006986 response to unfolded protein; GO:0045785 positive regulation of cell adhesion; GO:0051084 'de novo' posttranslational protein folding; GO:0006950 response to stress; GO:0032496 response to lipopolysaccharide; GO:0008283 cell proliferation; GO:0032101 regulation of response to external stimulus; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:1903039 positive regulation of leukocyte cell-cell adhesion; GO:0002263 cell activation involved"}},"GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0098857 membrane microdomain; GO:0005737 cytoplasm; GO:0044438 microbody part; GO:0032991 macromolecular complex; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0070062 extracellular exosome; GO:0043209 myelin sheath; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0098589 membrane region; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0043233 organelle lumen; GO:0005759 mitochondrial matrix; GO:0044439 peroxisomal part; GO:0005791 rough endoplasmic reticulum; GO:0031967 organelle envelope; GO:0043235 receptor complex; GO:0030135 coated vesicle; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0031012 extracellular matrix; GO:0043231 intracellular membrane-bounded organelle; GO:0030061 mitochondrial crista; GO:0031975 envelope; GO:0005905 clathrin-coated pit; GO:0043234 protein complex; GO:0031966 mitochondrial membrane; GO:0043230 extracellular organelle; GO:0005783 endoplasmic reticulum; GO:0005615 extracellular space; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0042588 zymogen granule; GO:0031982 vesicle; GO:0046696 lipopolysaccharide receptor complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0005782 peroxisomal matrix; GO:0044464 cell part; GO:0044425 membrane part; GO:0042579 microbody; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0019866 organelle inner membrane; GO:0005768 endosome; GO:0030141 secretory granule; GO:0045121 membrane raft; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0005777 peroxisome; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0016021 integral component of membrane; GO:0043226 organelle; GO:0031907 microbody lumen; GO:0009986 cell surface; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0031625 ubiquitin protein ligase binding; GO:0042562 hormone binding; GO:0003690 double-stranded DNA binding; GO:0046983 protein dimerization activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0003697 single-stranded DNA binding; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0044183 protein binding involved in protein folding; GO:0016887 ATPase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0042277 peptide binding; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0008289 lipid binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003688 DNA replication origin binding; GO:0003723 RNA binding; GO:0003677 DNA binding; GO:0005524 ATP binding; GO:0046982 protein heterodimerization activity; GO:0051087 chaperone binding; GO:0003725 double-stranded RNA binding; GO:0044877 macromolecular complex binding; GO:1990837 sequence-specific double-stranded DNA binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0043559 insulin binding; GO:0051787 misfolded protein binding; GO:0033218 amide binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0017046 peptide hormone binding; GO:0043565 sequence-specific DNA binding; GO:0002020 protease binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0002039 p53 binding; GO:0003676 nucleic acid binding; GO:0001530 lipopolysaccharide binding; GO:0032555 purine ribonucleotide binding; GO:0051082 unfolded protein binding; GO:0001883 purine nucleoside binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0019899 enzyme binding; GO:0032403 protein complex binding; GO:0036094 small molecule binding; ","K04077","groEL; chaperonin GroEL","hsa03018 RNA degradation - Homo sapiens (human); hsa05134 Legionellosis - Homo sapiens (human); hsa05152 Tuberculosis - Homo sapiens (human); hsa04940 Type I diabetes mellitus - Homo sapiens (human); ","IPR027409; IPR027413; ","GroEL-like apical domain; GroEL-like equatorial domain; \r"]
["P10909","Clusterin OS=Homo sapiens OX=9606 GN=CLU","CLU",52.494,101.67,24.5,10,18,10,1.044,0.996,0.959,1.014,0.973,0.977,0.988,0.706,"extracellular\r",{"$cut":{"chars":16791,"head":"GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:1902430 negative regulation of beta-amyloid formation; GO:0010941 regulation of cell death; GO:1905892 negative regulation of cellular response to thapsigargin; GO:0007272 ensheathment of neurons; GO:0032680 regulation of tumor necrosis factor production; GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0090201 negative regulation of release of cytochrome c from mitochondria; GO:0009891 positive regulation of biosynthetic process; GO:1905897 regulation of response to endoplasmic reticulum stress; GO:0010821 regulation of mitochondrion organization; GO:0009607 response to biotic stimulus; GO:1903364 positive regulation of cellular protein catabolic process; GO:0008152 metabolic process; GO:0065003 macromolecular complex assembly; GO:0044093 positive regulation of molecular function; GO:1902996 regulation of neurofibrillary tangle assembly; GO:0006958 complement activation, classical pathway; GO:0031333 negative regulation of protein complex assembly; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0034249 negative regulation of cellular amide metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0051704 multi-organism process; GO:1905907 negative regulation of amyloid fibril formation; GO:0050776 regulation of immune response; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0006810 transport; GO:0032291 axon ensheathment in central nervous system; GO:0051092 positive regulation of NF-kappaB transcription factor activity; GO:0042063 gliogenesis; GO:1902532 negative regulation of intracellular signal transduction; GO:0080135 regulation of cellular response to stress; GO:0061136 regulation of proteasomal protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0060548 negative regulation of cell death; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0044707 single-multicellular organism process; GO:0097190 apoptotic signaling pathway; GO:0001819 positive regulation of cytokine production; GO:0002576 platelet degranulation; GO:0048519 negative regulation of biological process; GO:1902947 regulation of tau-protein kinase activity; GO:0019724 B cell mediated immunity; GO:0009653 anatomical structure morphogenesis; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0009889 regulation of biosynthetic process; GO:0009896 positive regulation of catabolic process; GO:0042176 regulation of protein catabolic process; GO:0002449 lymphocyte mediated immunity; GO:1902993 positive regulation of amyloid precursor protein catabolic process; GO:0050778 positive regulation of immune response; GO:0006950 response to stress; GO:0008283 cell proliferation; GO:0032462 regulation of protein homooligomerization; GO:0010876 lipid localization; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:1902004 positive regulation of beta-amyloid formation; GO:0034248 regulation of cellular amide metabolic process; GO:0045055 regulated exocytosis; GO:0031398 positive regulation of protein ubiquitination; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0031647 regulation of protein stability; GO:0006955 immune response; GO:0050821 protein stabilization; GO:0010256 endomembrane system organization; GO:0015850 organic hydroxy compound transport; GO:0009968 negative regulation of signal transduction; GO:0030301 cholesterol transport; GO:0017038 protein import; GO:0048869 cellular developmental process; GO:0031331 positive regulation of cellular catabolic process; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0031396 regulation of protein ubiquitination; GO:2001141 regulation of RNA"}},"GO:0030425 dendrite; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:1990777 lipoprotein particle; GO:0099503 secretory vesicle; GO:0043005 neuron projection; GO:0097418 neurofibrillary tangle; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043233 organelle lumen; GO:0042995 cell projection; GO:0016234 inclusion body; GO:0031967 organelle envelope; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0031012 extracellular matrix; GO:0031975 envelope; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0031966 mitochondrial membrane; GO:0034774 secretory granule lumen; GO:0005615 extracellular space; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0034358 plasma lipoprotein particle; GO:0044424 intracellular part; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0032994 protein-lipid complex; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0030141 secretory granule; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0044429 mitochondrial part; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0034364 high-density lipoprotein particle; GO:0005829 cytosol; GO:0042583 chromaffin granule; GO:0043226 organelle; GO:0005634 nucleus; GO:0072562 blood microparticle; GO:0036477 somatodendritic compartment; GO:0060205 cytoplasmic vesicle lumen; GO:0034366 spherical high-density lipoprotein particle; GO:0097440 apical dendrite; GO:0031093 platelet alpha granule lumen; GO:0009986 cell surface; GO:0031091 platelet alpha granule; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:0051787 misfolded protein binding; GO:0005515 protein binding; GO:0031625 ubiquitin protein ligase binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0051087 chaperone binding; GO:0005488 binding; GO:0019899 enzyme binding; ","K17252","CLU; clusterin","hsa04610 Complement and coagulation cascades - Homo sapiens (human); ","IPR016015; IPR016014; ","\"Clusterin, C-terminal; Clusterin, N-terminal; \"\r"]
["P10916","Myosin regulatory light chain 2, ventricular/cardiac muscle isoform OS=Homo sapiens OX=9606 GN=MYL2","MYL2",18.789,35.355,37.3,5,7,5,0.507,0.518,1.228,1.315,1.254,1.205,1.675,0.174,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0030048 actin filament-based movement; GO:0065008 regulation of biological quality; GO:0070252 actin-mediated cell contraction; GO:0003012 muscle system process; GO:0048747 muscle fiber development; GO:0060415 muscle tissue morphogenesis; GO:0048869 cellular developmental process; GO:0032989 cellular component morphogenesis; GO:0044699 single-organism process; GO:0001558 regulation of cell growth; GO:0030036 actin cytoskeleton organization; GO:0048729 tissue morphogenesis; GO:0007507 heart development; GO:0022607 cellular component assembly; GO:0003208 cardiac ventricle morphogenesis; GO:0044057 regulation of system process; GO:0042693 muscle cell fate commitment; GO:0001708 cell fate specification; GO:0055013 cardiac muscle cell development; GO:0055003 cardiac myofibril assembly; GO:0032502 developmental process; GO:0031032 actomyosin structure organization; GO:0045926 negative regulation of growth; GO:0009888 tissue development; GO:0060537 muscle tissue development; GO:0055008 cardiac muscle tissue morphogenesis; GO:0003007 heart morphogenesis; GO:0044763 single-organism cellular process; GO:0006941 striated muscle contraction; GO:0090257 regulation of muscle system process; GO:0032501 multicellular organismal process; GO:0006942 regulation of striated muscle contraction; GO:0030308 negative regulation of cell growth; GO:1902589 single-organism organelle organization; GO:0048513 animal organ development; GO:0003229 ventricular cardiac muscle tissue development; GO:0050789 regulation of biological process; GO:0055002 striated muscle cell development; GO:0007517 muscle organ development; GO:0048644 muscle organ morphogenesis; GO:0009887 animal organ morphogenesis; GO:0003015 heart process; GO:0098735 positive regulation of the force of heart contraction; GO:0003013 circulatory system process; GO:0097435 supramolecular fiber organization; GO:0048856 anatomical structure development; GO:0055001 muscle cell development; GO:0072359 circulatory system development; GO:0050794 regulation of cellular process; GO:0014706 striated muscle tissue development; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0055006 cardiac cell development; GO:0030049 muscle filament sliding; GO:0040008 regulation of growth; GO:0048738 cardiac muscle tissue development; GO:1903522 regulation of blood circulation; GO:0009791 post-embryonic development; GO:0008016 regulation of heart contraction; GO:0060048 cardiac muscle contraction; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0048468 cell development; GO:0051239 regulation of multicellular organismal process; GO:0055007 cardiac muscle cell differentiation; GO:0009653 anatomical structure morphogenesis; GO:0030154 cell differentiation; GO:0006936 muscle contraction; GO:0070925 organelle assembly; GO:0055010 ventricular cardiac muscle tissue morphogenesis; GO:0030239 myofibril assembly; GO:0008015 blood circulation; GO:0061061 muscle structure development; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0060047 heart contraction; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0003231 cardiac ventricle development; GO:0009987 cellular process; GO:0042694 muscle cell fate specification; GO:0051146 striated muscle cell differentiation; GO:0035051 cardiocyte differentiation; GO:0003008 system process; GO:0033275 actin-myosin filament sliding; GO:0048731 system development; GO:0010927 cellular component assembly involved in morphogenesis; GO:0006937 regulation of muscle contraction; GO:0003206 cardiac chamber morphogenesis; GO:0003205 cardiac chamber development; GO:0045165 cell fate commitment; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0030029 actin filament-based process; GO:0002026 regulation of the force of heart contraction; GO:0006928 movement of cell or subcellular component; GO:0042692 muscle cell differentiation; GO:0051128 regulation of cellular component organization; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0030016 myofibril; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0015629 actin cytoskeleton; GO:0044422 organelle part; GO:0099081 supramolecular polymer; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0043226 organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0031672 A band; GO:0030017 sarcomere; GO:0043292 contractile fiber; GO:0044449 contractile fiber part; GO:0016459 myosin complex; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0008092 cytoskeletal protein binding; GO:0003785 actin monomer binding; GO:0032036 myosin heavy chain binding; GO:0005488 binding; GO:0043167 ion binding; GO:0003779 actin binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0005509 calcium ion binding; GO:0017022 myosin binding; GO:0005198 structural molecule activity; GO:0008307 structural constituent of muscle; ","K10351","MYL2; myosin regulatory light chain 2","hsa04260 Cardiac muscle contraction - Homo sapiens (human); hsa04670 Leukocyte transendothelial migration - Homo sapiens (human); hsa05414 Dilated cardiomyopathy (DCM) - Homo sapiens (human); hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa04371 Apelin signaling pathway - Homo sapiens (human); hsa04530 Tight junction - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa05410 Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human); ","IPR011992; IPR002048; ","EF-hand domain pair; EF-hand domain; \r"]
["P11021","Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5","HSPA5",72.332,293.07,48,32,84,30,0.985,0.978,0.978,1.019,1.029,1.014,1.041,0.00122,"endoplasmic reticulum\r","GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0009891 positive regulation of biosynthetic process; GO:0046683 response to organophosphorus; GO:0032091 negative regulation of protein binding; GO:1905897 regulation of response to endoplasmic reticulum stress; GO:0044237 cellular metabolic process; GO:0009607 response to biotic stimulus; GO:0021762 substantia nigra development; GO:0008152 metabolic process; GO:0070972 protein localization to endoplasmic reticulum; GO:0044093 positive regulation of molecular function; GO:0051220 cytoplasmic sequestering of protein; GO:0021587 cerebellum morphogenesis; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0021575 hindbrain morphogenesis; GO:0060359 response to ammonium ion; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0090287 regulation of cellular response to growth factor stimulus; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0010243 response to organonitrogen compound; GO:0051591 response to cAMP; GO:0080135 regulation of cellular response to stress; GO:0030163 protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:1901698 response to nitrogen compound; GO:0044260 cellular macromolecule metabolic process; GO:0060548 negative regulation of cell death; GO:0010975 regulation of neuron projection development; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:1903332 regulation of protein folding; GO:0044707 single-multicellular organism process; GO:0009267 cellular response to starvation; GO:1901700 response to oxygen-containing compound; GO:0048519 negative regulation of biological process; GO:1900101 regulation of endoplasmic reticulum unfolded protein response; GO:0009653 anatomical structure morphogenesis; GO:0042493 response to drug; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0051345 positive regulation of hydrolase activity; GO:0009889 regulation of biosynthetic process; GO:2000145 regulation of cell motility; GO:1903891 regulation of ATF6-mediated unfolded protein response; GO:0043620 regulation of DNA-templated transcription in response to stress; GO:0044248 cellular catabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0034613 cellular protein localization; GO:0030902 hindbrain development; GO:0006986 response to unfolded protein; GO:1990089 response to nerve growth factor; GO:0006950 response to stress; GO:0051270 regulation of cellular component movement; GO:0042149 cellular response to glucose starvation; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0043496 regulation of protein homodimerization activity; GO:0010033 response to organic substance; GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0048532 anatomical structure arrangement; GO:0031398 positive regulation of protein ubiquitination; GO:0097501 stress response to metal ion; GO:0090074 negative regulation of protein homodimerization activity; GO:0031325 positive regulation of cellular metabolic process; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:1902074 response to salt; GO:0036499 PERK-mediated unfolded protein response; GO:0009968 negative regulation of signal transduction; GO:0040017 positive regulation of locomotion; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0030968 endoplasmic reticulum unfolded protein response; GO:0031396 regulation of protein ubiquitination; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0009893 positive regulation of metabolic process; GO:0071287 cellular response to manganese ion; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0006915 apoptotic process; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0033036 macromolecule localization; GO:0033674 positive regulation of kinase activity; GO:0051402 neuron apoptotic process; GO:0045937 positive regulation of phosphate metabolic process; GO:0031326 regulation of cellular biosynthetic process; GO:0034097 response to cytokine; GO:0051098 regulation of binding; GO:0023052 signaling; GO:0010038 response to metal ion; GO:0071417 cellular response to organonitrogen compound; GO:0045664 regulation of neuron differentiation; GO:1904313 response to methamphetamine hydrochloride; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0043549 regulation of kinase activity; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0043069 negative regulation of programmed cell death; GO:0044257 cellular protein catabolic process; GO:0035967 cellular response to topologically incorrect protein; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:0060255 regulation of macromolecule metabolic process; GO:0017015 regulation of transforming growth factor beta receptor signaling pathway; GO:0071310 cellular response to organic substance; GO:0046677 response to antibiotic; GO:0036498 IRE1-mediated unfolded protein response; GO:0031669 cellular response to nutrient levels; GO:0010498 proteasomal protein catabolic process; GO:0071704 organic substance metabolic process; GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0030154 cell differentiation; GO:0043066 negative regulation of apoptotic process; GO:0090288 negative regulation of cellular response to growth factor stimulus; GO:0051592 response to calcium ion; GO:0010042 response to manganese ion; GO:0051235 maintenance of location; GO:0021589 cerebellum structural organization; GO:0045595 regulation of cell differentiation; GO:0006355 regulation of transcription, DNA-templated; GO:0045185 maintenance of protein location; GO:0019941 modification-dependent protein catabolic process; GO:0071320 cellular response to cAMP; GO:0001932 regulation of protein phosphorylation; GO:0006987 activation of signaling protein activity involved in unfolded protein response; GO:0001934 positive regulation of protein phosphorylation; GO:0043085 positive regulation of catalytic activity; GO:0060904 regulation of protein folding in endoplasmic reticulum; GO:1901701 cellular response to oxygen-containing compound; GO:0008219 cell death; GO:0035437 maintenance of protein localization in endoplasmic reticulum; GO:0071495 cellular response to endogenous stimulus; GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress; GO:0021577 hindbrain structural organization; GO:0042594 response to starvation; GO:0009056 catabolic process; GO:0042981 regulation of apoptotic process; GO:0050767 regulation of neurogenesis; GO:0065008 regulation of biological quality; GO:0030335 positive regulation of cell migration; GO:0032270 positive regulation of cellular protein metabolic process; GO:0070997 neuron death; GO:0007420 brain development; GO:1903894 regulation of IRE1-mediated unfolded protein response; GO:0036503 ERAD pathway; GO:1903845 negative regulation of cellular response to transforming growth factor beta stimulus; GO:0071345 cellular response to cytokine stimulus; GO:0048857 neural nucleus development; GO:0072595 maintenance of protein localization in organelle; GO:0009605 response to external stimulus; GO:0035966 response to topologically incorrect protein; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0009719 response to endogenous stimulus; GO:0070848 response to growth factor; GO:0010562 positive regulation of phosphorus metabolic process; GO:0042327 positive regulation of phosphorylation; GO:0033365 protein localization to organelle; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0051347 positive regulation of transferase activity; GO:0051651 maintenance of location in cell; GO:0008104 protein localization; GO:0007399 nervous system development; GO:0014070 response to organic cyclic compound; GO:0030901 midbrain development; GO:0051174 regulation of phosphorus metabolic process; GO:0032507 maintenance of protein location in cell; GO:0031346 positive regulation of cell projection organization; GO:0045893 positive regulation of transcription, DNA-templated; GO:0051272 positive regulation of cellular component movement; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0071353 cellular response to interleukin-4; GO:0021549 cerebellum development; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0051336 regulation of hydrolase activity; GO:0007417 central nervous system development; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0010604 positive regulation of macromolecule metabolic process; GO:0021695 cerebellar cortex development; GO:0051094 positive regulation of developmental process; GO:0042220 response to cocaine; GO:0036500 ATF6-mediated unfolded protein response; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0034976 response to endoplasmic reticulum stress; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0043067 regulation of programmed cell death; GO:0043279 response to alkaloid; GO:0032075 positive regulation of nuclease activity; GO:0080134 regulation of response to stress; GO:2000147 positive regulation of cell motility; GO:0048523 negative regulation of cellular process; GO:0045597 positive regulation of cell differentiation; GO:0051239 regulation of multicellular organismal process; GO:0032069 regulation of nuclease activity; GO:1902578 single-organism localization; GO:0010628 positive regulation of gene expression; GO:0014074 response to purine-containing compound; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:0070670 response to interleukin-4; GO:0006983 ER overload response; GO:0051254 positive regulation of RNA metabolic process; GO:0048731 system development; GO:0030334 regulation of cell migration; GO:0071496 cellular response to external stimulus; GO:0071407 cellular response to organic cyclic compound; GO:0044238 primary metabolic process; GO:0006984 ER-nucleus signaling pathway; GO:0031668 cellular response to extracellular stimulus; GO:0030182 neuron differentiation; GO:0051247 positive regulation of protein metabolic process; GO:0010976 positive regulation of neuron projection development; GO:0050769 positive regulation of neurogenesis; GO:0012501 programmed cell death; GO:0031328 positive regulation of cellular biosynthetic process; GO:0051179 localization; GO:0071248 cellular response to metal ion; GO:0050793 regulation of developmental process; GO:0045666 positive regulation of neuron differentiation; GO:0022008 neurogenesis; GO:1901998 toxin transport; GO:0071363 cellular response to growth factor stimulus; GO:0051234 establishment of localization; GO:0006457 protein folding; GO:0051130 positive regulation of cellular component organization; GO:0010646 regulation of cell communication; GO:0030433 ubiquitin-dependent ERAD pathway; GO:0007154 cell communication; GO:0009314 response to radiation; GO:0060322 head development; GO:0010035 response to inorganic substance; GO:0010720 positive regulation of cell development; GO:1903897 regulation of PERK-mediated unfolded protein response; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0051962 positive regulation of nervous system development; GO:0048522 positive regulation of cellular process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0021680 cerebellar Purkinje cell layer development; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0036003 positive regulation of transcription from RNA polymerase II promoter in response to stress; GO:1901699 cellular response to nitrogen compound; GO:0051100 negative regulation of binding; GO:0071241 cellular response to inorganic substance; GO:0019222 regulation of metabolic process; GO:0022037 metencephalon development; GO:0019220 regulation of phosphate metabolic process; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0045859 regulation of protein kinase activity; GO:0035690 cellular response to drug; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031344 regulation of cell projection organization; GO:0034975 protein folding in endoplasmic reticulum; GO:0050896 response to stimulus; GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0009991 response to extracellular stimulus; GO:0043393 regulation of protein binding; GO:1903322 positive regulation of protein modification by small protein conjugation or removal; GO:0071216 cellular response to biotic stimulus; GO:0006508 proteolysis; GO:0009987 cellular process; GO:0043632 modification-dependent macromolecule catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0034620 cellular response to unfolded protein; GO:0044712 single-organism catabolic process; GO:1990090 cellular response to nerve growth factor stimulus; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0071277 cellular response to calcium ion; GO:0031401 positive regulation of protein modification process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway; GO:0045860 positive regulation of protein kinase activity; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:1903844 regulation of cellular response to transforming growth factor beta stimulus; GO:0070727 cellular macromolecule localization; GO:0071236 cellular response to antibiotic; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0009057 macromolecule catabolic process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0051128 regulation of cellular component organization; GO:0031667 response to nutrient levels; GO:0040012 regulation of locomotion; GO:0065007 biological regulation; ","GO:0005790 smooth endoplasmic reticulum; GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0048770 pigment granule; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0070013 intracellular organelle lumen; GO:0005925 focal adhesion; GO:0044425 membrane part; GO:0043209 myelin sheath; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0031227 intrinsic component of endoplasmic reticulum membrane; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043233 organelle lumen; GO:0005924 cell-substrate adherens junction; GO:0097708 intracellular vesicle; GO:0005788 endoplasmic reticulum lumen; GO:0043229 intracellular organelle; GO:0042470 melanosome; GO:0044446 intracellular organelle part; GO:0030496 midbody; GO:0070161 anchoring junction; GO:0012505 endomembrane system; GO:0034663 endoplasmic reticulum chaperone complex; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0031012 extracellular matrix; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044432 endoplasmic reticulum part; GO:0005793 endoplasmic reticulum-Golgi intermediate compartment; GO:0009986 cell surface; GO:0043234 protein complex; GO:0030176 integral component of endoplasmic reticulum membrane; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0031625 ubiquitin protein ligase binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0016887 ATPase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0051087 chaperone binding; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0051787 misfolded protein binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0043022 ribosome binding; GO:0050839 cell adhesion molecule binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0046872 metal ion binding; GO:0019904 protein domain specific binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0051082 unfolded protein binding; GO:0005509 calcium ion binding; GO:0001948 glycoprotein binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0043021 ribonucleoprotein complex binding; GO:0019899 enzyme binding; GO:0036094 small molecule binding; ","K09490","HSPA5; heat shock 70kDa protein 5","hsa03060 Protein export - Homo sapiens (human); hsa04918 Thyroid hormone synthesis - Homo sapiens (human); hsa04612 Antigen processing and presentation - Homo sapiens (human); hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); hsa05020 Prion diseases - Homo sapiens (human); ","IPR029048; IPR029047; ","\"Heat shock protein 70kD, C-terminal domain; Heat shock protein 70kD, peptide-binding domain; \"\r"]
["P11047","Laminin subunit gamma-1 OS=Homo sapiens OX=9606 GN=LAMC1","LAMC1",177.6,215.26,20.9,27,38,27,1.124,1.103,1.124,0.922,0.899,0.911,0.815,2.46e-05,"extracellular\r","GO:0050794 regulation of cellular process; GO:0044085 cellular component biogenesis; GO:0034329 cell junction assembly; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0016477 cell migration; GO:0042127 regulation of cell proliferation; GO:0051674 localization of cell; GO:0048869 cellular developmental process; GO:0032989 cellular component morphogenesis; GO:0044699 single-organism process; GO:0048468 cell development; GO:0000904 cell morphogenesis involved in differentiation; GO:0007492 endoderm development; GO:0071711 basement membrane organization; GO:0009653 anatomical structure morphogenesis; GO:0022610 biological adhesion; GO:0034446 substrate adhesion-dependent cell spreading; GO:0030154 cell differentiation; GO:0022607 cellular component assembly; GO:0050678 regulation of epithelial cell proliferation; GO:0065003 macromolecular complex assembly; GO:0043062 extracellular structure organization; GO:0022617 extracellular matrix disassembly; GO:0007155 cell adhesion; GO:0030198 extracellular matrix organization; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0032502 developmental process; GO:0007044 cell-substrate junction assembly; GO:0071822 protein complex subunit organization; GO:0009888 tissue development; GO:0048731 system development; GO:0070831 basement membrane assembly; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0048870 cell motility; GO:0085029 extracellular matrix assembly; GO:0048518 positive regulation of biological process; GO:0032501 multicellular organismal process; GO:0043933 macromolecular complex subunit organization; GO:0000902 cell morphogenesis; GO:0050789 regulation of biological process; GO:0034330 cell junction organization; GO:0031589 cell-substrate adhesion; GO:0031581 hemidesmosome assembly; GO:0044767 single-organism developmental process; GO:0098602 single organism cell adhesion; GO:0022411 cellular component disassembly; GO:0006928 movement of cell or subcellular component; GO:0040011 locomotion; GO:0070271 protein complex biogenesis; GO:0051179 localization; GO:0048856 anatomical structure development; GO:0008284 positive regulation of cell proliferation; GO:0065007 biological regulation; GO:0050679 positive regulation of epithelial cell proliferation; GO:0071840 cellular component organization or biogenesis; ","GO:0043260 laminin-11 complex; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005606 laminin-1 complex; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0044420 extracellular matrix component; GO:0005576 extracellular region; GO:0043256 laminin complex; GO:0005604 basement membrane; GO:0005605 basal lamina; GO:0031012 extracellular matrix; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:1903561 extracellular vesicle; GO:0005578 proteinaceous extracellular matrix; GO:0043259 laminin-10 complex; GO:0043227 membrane-bounded organelle; GO:0043234 protein complex; GO:0043230 extracellular organelle; ","GO:0005201 extracellular matrix structural constituent; GO:0005515 protein binding; GO:0005198 structural molecule activity; GO:0005488 binding; ","K05635","LAMC1; laminin, gamma 1","hsa05200 Pathways in cancer - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa05146 Amoebiasis - Homo sapiens (human); hsa05020 Prion diseases - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa05222 Small cell lung cancer - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa04512 ECM-receptor interaction - Homo sapiens (human); hsa05145 Toxoplasmosis - Homo sapiens (human); ","IPR000034; IPR002049; IPR000742; IPR008211; IPR008979; ","\"Laminin IV; Laminin EGF domain; EGF-like domain; Laminin, N-terminal; Galactose-binding domain-like; \"\r"]
["P11142","Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8","HSPA8",70.897,323.01,49.7,35,110,22,0.91,0.912,0.898,1.099,1.1,1.105,1.215,1.43e-06,"cytoplasm\r","GO:0044700 single organism signaling; GO:0010608 posttranscriptional regulation of gene expression; GO:0006623 protein targeting to vacuole; GO:0006914 autophagy; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0006396 RNA processing; GO:0044794 positive regulation by host of viral process; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0071806 protein transmembrane transport; GO:0044763 single-organism cellular process; GO:0072319 vesicle uncoating; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0051704 multi-organism process; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0080135 regulation of cellular response to stress; GO:0007267 cell-cell signaling; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0030163 protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0051223 regulation of protein transport; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0016071 mRNA metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0033120 positive regulation of RNA splicing; GO:0009267 cellular response to starvation; GO:0009259 ribonucleotide metabolic process; GO:0048519 negative regulation of biological process; GO:0061740 protein targeting to lysosome involved in chaperone-mediated autophagy; GO:0043487 regulation of RNA stability; GO:0051817 modification of morphology or physiology of other organism involved in symbiotic interaction; GO:0045892 negative regulation of transcription, DNA-templated; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0043624 cellular protein complex disassembly; GO:0044248 cellular catabolic process; GO:0051702 interaction with symbiont; GO:0034613 cellular protein localization; GO:0006986 response to unfolded protein; GO:0051084 'de novo' posttranslational protein folding; GO:0006950 response to stress; GO:0032984 macromolecular complex disassembly; GO:0002376 immune system process; GO:0009141 nucleoside triphosphate metabolic process; GO:0010033 response to organic substance; GO:0002263 cell activation involved in immune response; GO:1901576 organic substance biosynthetic process; GO:0061635 regulation of protein complex stability; GO:0006163 purine nucleotide metabolic process; GO:0043484 regulation of RNA splicing; GO:0045055 regulated exocytosis; GO:0009890 negative regulation of biosynthetic process; GO:0099536 synaptic signaling; GO:0043414 macromolecule methylation; GO:0031325 positive regulation of cellular metabolic process; GO:0019637 organophosphate metabolic process; GO:0031647 regulation of protein stability; GO:0006955 immune response; GO:0043412 macromolecule modification; GO:0007268 chemical synaptic transmission; GO:0001505 regulation of neurotransmitter levels; GO:0072594 establishment of protein localization to organelle; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0051253 negative regulation of RNA metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0032259 methylation; GO:0043241 protein complex disassembly; GO:2001141 regulation of RNA biosynthetic process; GO:0009893 positive regulation of metabolic process; GO:0072666 establishment of protein localization to vacuole; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0098916 anterograde trans-synaptic signaling; GO:0033036 macromolecule localization; GO:0051726 regulation of cell cycle; GO:0048024 regulation of mRNA splicing, via spliceosome; GO:0034486 vacuolar transmembrane transport; GO:1903902 positive regulation of viral life cycle; GO:0043902 positive regulation of multi-organism process; GO:0031326 regulation of cellular biosynthetic process; GO:0023052 signaling; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0044788 modulation by host of viral process; GO:0002444 myeloid leukocyte mediated immunity; GO:0006351 transcription, DNA-templated; GO:0032940 secretion by cell; GO:1902679 negative regulation of RNA biosynthetic process; GO:1900034 regulation of cellular response to heat; GO:0036211 protein modification process; GO:0051851 modification by host of symbiont morphology or physiology; GO:0042026 protein refolding; GO:0016043 cellular component organization; GO:0060255 regulation of macromolecule metabolic process; GO:1904589 regulation of protein import; GO:0031669 cellular response to nutrient levels; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0061741 chaperone-mediated protein transport involved in chaperone-mediated autophagy; GO:0016032 viral process; GO:0006886 intracellular protein transport; GO:0099537 trans-synaptic signaling; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0045070 positive regulation of viral genome replication; GO:0046034 ATP metabolic process; GO:0051261 protein depolymerization; GO:0051085 chaperone mediated protein folding requiring cofactor; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0051049 regulation of transport; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0043488 regulation of mRNA stability; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0002366 leukocyte activation involved in immune response; GO:0046128 purine ribonucleoside metabolic process; GO:0042119 neutrophil activation; GO:0048524 positive regulation of viral process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0007034 vacuolar transport; GO:0048026 positive regulation of mRNA splicing, via spliceosome; GO:0010467 gene expression; GO:0042594 response to starvation; GO:0031327 negative regulation of cellular biosynthetic process; GO:0009056 catabolic process; GO:0006836 neurotransmitter transport; GO:0071840 cellular component organization or biogenesis; GO:0065008 regulation of biological quality; GO:0009116 nucleoside metabolic process; GO:0044827 modulation by host of viral genome replication; GO:0045321 leukocyte activation; GO:0097659 nucleic acid-templated transcription; GO:0007269 neurotransmitter secretion; GO:0015031 protein transport; GO:0009605 response to external stimulus; GO:0008213 protein alkylation; GO:0006458 'de novo' protein folding; GO:0035966 response to topologically incorrect protein; GO:0032879 regulation of localization; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0033365 protein localization to organelle; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0044419 interspecies interaction between organisms; GO:0008104 protein localization; GO:0072321 chaperone-mediated protein transport; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0018130 heterocycle biosynthetic process; GO:0061462 protein localization to lysosome; GO:0002443 leukocyte mediated immunity; GO:0044281 small molecule metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0050684 regulation of mRNA processing; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0072665 protein localization to vacuole; GO:1903506 regulation of nucleic acid-templated transcription; GO:0044710 single-organism metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:1904764 chaperone-mediated autophagy translocation complex disassembly; GO:0006464 cellular protein modification process; GO:0009126 purine nucleoside monophosphate metabolic process; GO:0099643 signal release from synapse; GO:1901362 organic cyclic compound biosynthetic process; GO:1902903 regulation of supramolecular fiber organization; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0046907 intracellular transport; GO:0002283 neutrophil activation involved in immune response; GO:0044267 cellular protein metabolic process; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:0071211 protein targeting to vacuole involved in autophagy; GO:1902578 single-organism localization; GO:0006479 protein methylation; GO:0002275 myeloid cell activation involved in immune response; GO:0019438 aromatic compound biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0000375 RNA splicing, via transesterification reactions; GO:0051171 regulation of nitrogen compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0032880 regulation of protein localization; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0008380 RNA splicing; GO:0009119 ribonucleoside metabolic process; GO:0051254 positive regulation of RNA metabolic process; GO:0016192 vesicle-mediated transport; GO:0043900 regulation of multi-organism process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0023061 signal release; GO:0071496 cellular response to external stimulus; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0031668 cellular response to extracellular stimulus; GO:0045184 establishment of protein localization; GO:0055085 transmembrane transport; GO:1903311 regulation of mRNA metabolic process; GO:0006793 phosphorus metabolic process; GO:0061024 membrane organization; GO:0001775 cell activation; GO:0051179 localization; GO:0006887 exocytosis; GO:1901564 organonitrogen compound metabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0051129 negative regulation of cellular component organization; GO:0009117 nucleotide metabolic process; GO:0061077 chaperone-mediated protein folding; GO:0044764 multi-organism cellular process; GO:0035821 modification of morphology or physiology of other organism; GO:0051234 establishment of localization; GO:0006457 protein folding; GO:0006605 protein targeting; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0006753 nucleoside phosphate metabolic process; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0002274 myeloid leukocyte activation; GO:0010468 regulation of gene expression; GO:0071822 protein complex subunit organization; GO:0002446 neutrophil mediated immunity; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0045069 regulation of viral genome replication; GO:1903313 positive regulation of mRNA metabolic process; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:0043254 regulation of protein complex assembly; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0090304 nucleic acid metabolic process; GO:1902904 negative regulation of supramolecular fiber organization; GO:0019222 regulation of metabolic process; GO:0043299 leukocyte degranulation; GO:1901657 glycosyl compound metabolic process; GO:0061684 chaperone-mediated autophagy; GO:0050685 positive regulation of mRNA processing; GO:0006725 cellular aromatic compound metabolic process; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0002252 immune effector process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0099531 presynaptic process involved in chemical synaptic transmission; GO:0044087 regulation of cellular component biogenesis; GO:0072318 clathrin coat disassembly; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0070201 regulation of establishment of protein localization; GO:0009991 response to extracellular stimulus; GO:0006622 protein targeting to lysosome; GO:0036230 granulocyte activation; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0061738 late endosomal microautophagy; GO:0007041 lysosomal transport; GO:0050792 regulation of viral process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044829 positive regulation by host of viral genome replication; GO:0043312 neutrophil degranulation; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0070727 cellular macromolecule localization; GO:0009057 macromolecule catabolic process; GO:0022411 cellular component disassembly; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0031667 response to nutrient levels; GO:0051128 regulation of cellular component organization; GO:0009150 purine ribonucleotide metabolic process; GO:1903900 regulation of viral life cycle; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0000974 Prp19 complex; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0043228 non-membrane-bounded organelle; GO:0005765 lysosomal membrane; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0005654 nucleoplasm; GO:0005925 focal adhesion; GO:0030136 clathrin-coated vesicle; GO:0043209 myelin sheath; GO:0005622 intracellular; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:0030055 cell-substrate junction; GO:0061202 clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0098552 side of membrane; GO:0000323 lytic vacuole; GO:0005770 late endosome; GO:0070161 anchoring junction; GO:0012506 vesicle membrane; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005681 spliceosomal complex; GO:0098575 lumenal side of lysosomal membrane; GO:0043202 lysosomal lumen; GO:0030135 coated vesicle; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0031012 extracellular matrix; GO:0043231 intracellular membrane-bounded organelle; GO:0061200 clathrin-sculpted gamma-aminobutyric acid transport vesicle; GO:0060198 clathrin-sculpted vesicle; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0034774 secretory granule lumen; GO:0005615 extracellular space; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0030662 coated vesicle membrane; GO:0048770 pigment granule; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0098793 presynapse; GO:0044425 membrane part; GO:0044464 cell part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0005912 adherens junction; GO:0005768 endosome; GO:0030141 secretory granule; GO:0044456 synapse part; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0042470 melanosome; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0030665 clathrin-coated vesicle membrane; GO:0045202 synapse; GO:0098852 lytic vacuole membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0072562 blood microparticle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0098576 lumenal side of membrane; GO:0005774 vacuolar membrane; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0055131 C3HC4-type RING finger domain binding; GO:1901265 nucleoside phosphate binding; GO:0031625 ubiquitin protein ligase binding; GO:0005102 receptor binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0003823 antigen binding; GO:0001786 phosphatidylserine binding; GO:0016887 ATPase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0023023 MHC protein complex binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0023026 MHC class II protein complex binding; GO:0032550 purine ribonucleoside binding; GO:0008289 lipid binding; GO:0001664 G-protein coupled receptor binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003723 RNA binding; GO:0005524 ATP binding; GO:0031072 heat shock protein binding; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0050839 cell adhesion molecule binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0072341 modified amino acid binding; GO:0042623 ATPase activity, coupled; GO:0003676 nucleic acid binding; GO:0005543 phospholipid binding; GO:0032555 purine ribonucleotide binding; GO:0019904 protein domain specific binding; GO:0001883 purine nucleoside binding; GO:0051082 unfolded protein binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0019899 enzyme binding; GO:0032403 protein complex binding; GO:0036094 small molecule binding; ","K03283","HSPA1s; heat shock 70kDa protein 1/2/6/8","hsa03040 Spliceosome - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); hsa05020 Prion diseases - Homo sapiens (human); hsa05162 Measles - Homo sapiens (human); hsa05134 Legionellosis - Homo sapiens (human); hsa04010 MAPK signaling pathway - Homo sapiens (human); hsa04144 Endocytosis - Homo sapiens (human); hsa04612 Antigen processing and presentation - Homo sapiens (human); hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); hsa04213 Longevity regulating pathway - multiple species - Homo sapiens (human); hsa04915 Estrogen signaling pathway - Homo sapiens (human); hsa05145 Toxoplasmosis - Homo sapiens (human); hsa05164 Influenza A - Homo sapiens (human); ","IPR029048; IPR029047; ","\"Heat shock protein 70kD, C-terminal domain; Heat shock protein 70kD, peptide-binding domain; \"\r"]
["P11166","Solute carrier family 2, facilitated glucose transporter member 1 OS=Homo sapiens OX=9606 GN=SLC2A1","SLC2A1",54.083,40.456,9.1,6,12,6,0.828,0.872,0.858,1.159,1.103,1.116,1.321,0.000201,"plasma membrane\r","GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0050796 regulation of insulin secretion; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0051046 regulation of secretion; GO:0009058 biosynthetic process; GO:0005984 disaccharide metabolic process; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:0009605 response to external stimulus; GO:0034219 carbohydrate transmembrane transport; GO:0008152 metabolic process; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0044262 cellular carbohydrate metabolic process; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0032879 regulation of localization; GO:0015758 glucose transport; GO:0005988 lactose metabolic process; GO:0051180 vitamin transport; GO:0034637 cellular carbohydrate biosynthetic process; GO:0005989 lactose biosynthetic process; GO:0044765 single-organism transport; GO:0051716 cellular response to stimulus; GO:0006970 response to osmotic stress; GO:0071822 protein complex subunit organization; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0005975 carbohydrate metabolic process; GO:1903530 regulation of secretion by cell; GO:0006810 transport; GO:0044723 single-organism carbohydrate metabolic process; GO:0050789 regulation of biological process; GO:0046883 regulation of hormone secretion; GO:0044710 single-organism metabolic process; GO:0008645 hexose transport; GO:0046351 disaccharide biosynthetic process; GO:0010817 regulation of hormone levels; GO:0051223 regulation of protein transport; GO:0006082 organic acid metabolic process; GO:0070271 protein complex biogenesis; GO:0043436 oxoacid metabolic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0016043 cellular component organization; GO:0009267 cellular response to starvation; GO:0016051 carbohydrate biosynthetic process; GO:0015749 monosaccharide transport; GO:0009628 response to abiotic stimulus; GO:0050896 response to stimulus; GO:0031669 cellular response to nutrient levels; GO:0070201 regulation of establishment of protein localization; GO:0071704 organic substance metabolic process; GO:0009991 response to extracellular stimulus; GO:0006766 vitamin metabolic process; GO:0002791 regulation of peptide secretion; GO:1902578 single-organism localization; GO:0005996 monosaccharide metabolic process; GO:0008643 carbohydrate transport; GO:0070837 dehydroascorbic acid transport; GO:0009311 oligosaccharide metabolic process; GO:0032880 regulation of protein localization; GO:0050708 regulation of protein secretion; GO:0009987 cellular process; GO:0006767 water-soluble vitamin metabolic process; GO:0042908 xenobiotic transport; GO:0006461 protein complex assembly; GO:0019852 L-ascorbic acid metabolic process; GO:0090087 regulation of peptide transport; GO:0035428 hexose transmembrane transport; GO:0006950 response to stress; GO:0044711 single-organism biosynthetic process; GO:0042149 cellular response to glucose starvation; GO:0051049 regulation of transport; GO:0071496 cellular response to external stimulus; GO:0071702 organic substance transport; GO:0009312 oligosaccharide biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:1904659 glucose transmembrane transport; GO:0044249 cellular biosynthetic process; GO:0031668 cellular response to extracellular stimulus; GO:0043933 macromolecular complex subunit organization; GO:0006820 anion transport; GO:0055085 transmembrane transport; GO:0015711 organic anion transport; GO:0006811 ion transport; GO:0019752 carboxylic acid metabolic process; GO:0090276 regulation of peptide hormone secretion; GO:0042594 response to starvation; GO:0031667 response to nutrient levels; GO:0051179 localization; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0098857 membrane microdomain; GO:0099568 cytoplasmic region; GO:0005737 cytoplasm; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0098590 plasma membrane region; GO:0005622 intracellular; GO:0098589 membrane region; GO:0043227 membrane-bounded organelle; GO:0045177 apical part of cell; GO:0031226 intrinsic component of plasma membrane; GO:0044430 cytoskeletal part; GO:0030496 midbody; GO:0005901 caveola; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0016323 basolateral plasma membrane; GO:0005615 extracellular space; GO:0016324 apical plasma membrane; GO:0005938 cell cortex; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0031982 vesicle; GO:0030863 cortical cytoskeleton; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0030864 cortical actin cytoskeleton; GO:0005911 cell-cell junction; GO:0048770 pigment granule; GO:0005856 cytoskeleton; GO:0044425 membrane part; GO:0044464 cell part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0001939 female pronucleus; GO:0045121 membrane raft; GO:0045120 pronucleus; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0042470 melanosome; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0016021 integral component of membrane; GO:0015629 actin cytoskeleton; GO:0043226 organelle; GO:0072562 blood microparticle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0044448 cell cortex part; GO:0044853 plasma membrane raft; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:0055056 D-glucose transmembrane transporter activity; GO:0005355 glucose transmembrane transporter activity; GO:0043621 protein self-association; GO:0051119 sugar transmembrane transporter activity; GO:0042910 xenobiotic transporter activity; GO:1901476 carbohydrate transporter activity; GO:0022892 substrate-specific transporter activity; GO:0051183 vitamin transporter activity; GO:0005515 protein binding; GO:0015145 monosaccharide transmembrane transporter activity; GO:0019900 kinase binding; GO:0022891 substrate-specific transmembrane transporter activity; GO:0042802 identical protein binding; GO:0015144 carbohydrate transmembrane transporter activity; GO:0005488 binding; GO:0015149 hexose transmembrane transporter activity; GO:0019899 enzyme binding; GO:0033300 dehydroascorbic acid transporter activity; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; ","K07299","SLC2A1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1","hsa04920 Adipocytokine signaling pathway - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa04066 HIF-1 signaling pathway - Homo sapiens (human); hsa04922 Glucagon signaling pathway - Homo sapiens (human); hsa05230 Central carbon metabolism in cancer - Homo sapiens (human); hsa05211 Renal cell carcinoma - Homo sapiens (human); hsa05166 HTLV-I infection - Homo sapiens (human); hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human); hsa04976 Bile secretion - Homo sapiens (human); hsa04911 Insulin secretion - Homo sapiens (human); hsa04931 Insulin resistance - Homo sapiens (human); ","IPR020846; ","Major facilitator superfamily domain; \r"]
["P11171","Protein 4.1 OS=Homo sapiens OX=9606 GN=EPB41","EPB41",97.016,95.078,22,15,19,11,0.93,0.905,0.92,1.046,1.133,1.064,1.177,3.13E-3,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0031032 actomyosin structure organization; GO:0016043 cellular component organization; GO:0071822 protein complex subunit organization; GO:0030866 cortical actin cytoskeleton organization; GO:0032092 positive regulation of protein binding; GO:0051098 regulation of binding; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0030865 cortical cytoskeleton organization; GO:0043933 macromolecular complex subunit organization; GO:1902589 single-organism organelle organization; GO:0043393 regulation of protein binding; GO:0030036 actin cytoskeleton organization; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0006996 organelle organization; GO:0044093 positive regulation of molecular function; GO:0030029 actin filament-based process; GO:0065009 regulation of molecular function; GO:0070271 protein complex biogenesis; GO:0007010 cytoskeleton organization; GO:0051099 positive regulation of binding; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0005938 cell cortex; GO:0019898 extrinsic component of membrane; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0099568 cytoplasmic region; GO:0030863 cortical cytoskeleton; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0009898 cytoplasmic side of plasma membrane; GO:0098562 cytoplasmic side of membrane; GO:0032279 asymmetric synapse; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0014069 postsynaptic density; GO:0043227 membrane-bounded organelle; GO:0098984 neuron to neuron synapse; GO:0044456 synapse part; GO:0098552 side of membrane; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005829 cytosol; GO:0045202 synapse; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0098794 postsynapse; GO:0044448 cell cortex part; GO:0014731 spectrin-associated cytoskeleton; GO:0043234 protein complex; GO:0099572 postsynaptic specialization; GO:0044444 cytoplasmic part; ","GO:0008092 cytoskeletal protein binding; GO:0005545 1-phosphatidylinositol binding; GO:0005200 structural constituent of cytoskeleton; GO:0005488 binding; GO:0005543 phospholipid binding; GO:0035091 phosphatidylinositol binding; GO:0043167 ion binding; GO:0003779 actin binding; GO:0008289 lipid binding; GO:0005515 protein binding; GO:0043168 anion binding; GO:0005198 structural molecule activity; GO:0005516 calmodulin binding; GO:0030507 spectrin binding; ","K06107",null,null,"IPR019748; IPR018980; IPR018979; IPR019749; IPR008379; IPR029071; IPR011993; IPR007477; IPR014847; IPR014352; IPR000299; ","\"FERM central domain; FERM, C-terminal PH-like domain; FERM, N-terminal; Band 4.1 domain; Band 4.1, C-terminal; Ubiquitin-related domain; PH domain-like; SAB domain; FERM adjacent (FA); FERM/acyl-CoA-binding protein, 3-helical bundle; FERM domain; \"\r"]
["P11172","Uridine 5'-monophosphate synthase OS=Homo sapiens OX=9606 GN=UMPS","UMPS",52.221,56.192,20.2,8,10,8,0.943,1.014,0.908,1.023,1.081,1.014,1.088,0.0887,"mitochondria\r","GO:0046132 pyrimidine ribonucleoside biosynthetic process; GO:0009116 nucleoside metabolic process; GO:0065008 regulation of biological quality; GO:0048732 gland development; GO:0022414 reproductive process; GO:0009130 pyrimidine nucleoside monophosphate biosynthetic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0009163 nucleoside biosynthetic process; GO:0009156 ribonucleoside monophosphate biosynthetic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0046390 ribose phosphate biosynthetic process; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0006213 pyrimidine nucleoside metabolic process; GO:0046134 pyrimidine nucleoside biosynthetic process; GO:0006753 nucleoside phosphate metabolic process; GO:0044706 multi-multicellular organism process; GO:0046112 nucleobase biosynthetic process; GO:0072527 pyrimidine-containing compound metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0070887 cellular response to chemical stimulus; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0032502 developmental process; GO:0007595 lactation; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0006206 pyrimidine nucleobase metabolic process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0046131 pyrimidine ribonucleoside metabolic process; GO:0090407 organophosphate biosynthetic process; GO:0006810 transport; GO:0048513 animal organ development; GO:0009129 pyrimidine nucleoside monophosphate metabolic process; GO:0042221 response to chemical; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0006222 UMP biosynthetic process; GO:0009112 nucleobase metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0048856 anatomical structure development; GO:1901362 organic cyclic compound biosynthetic process; GO:0000003 reproduction; GO:0044707 single-multicellular organism process; GO:0035690 cellular response to drug; GO:0009165 nucleotide biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0009259 ribonucleotide metabolic process; GO:0046049 UMP metabolic process; GO:0044205 'de novo' UMP biosynthetic process; GO:0006221 pyrimidine nucleotide biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:0030879 mammary gland development; GO:0071704 organic substance metabolic process; GO:0072528 pyrimidine-containing compound biosynthetic process; GO:0007565 female pregnancy; GO:0042493 response to drug; GO:0009220 pyrimidine ribonucleotide biosynthetic process; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019856 pyrimidine nucleobase biosynthetic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0009173 pyrimidine ribonucleoside monophosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process; GO:0009119 ribonucleoside metabolic process; GO:0009987 cellular process; GO:0009218 pyrimidine ribonucleotide metabolic process; GO:0009124 nucleoside monophosphate biosynthetic process; GO:0007589 body fluid secretion; GO:0050878 regulation of body fluid levels; GO:0044711 single-organism biosynthetic process; GO:0048731 system development; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0042455 ribonucleoside biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0006220 pyrimidine nucleotide metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006793 phosphorus metabolic process; GO:1901659 glycosyl compound biosynthetic process; GO:0044767 single-organism developmental process; GO:0044703 multi-organism reproductive process; GO:0009174 pyrimidine ribonucleoside monophosphate biosynthetic process; GO:0009260 ribonucleotide biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0051179 localization; GO:0009123 nucleoside monophosphate metabolic process; GO:0065007 biological regulation; GO:1901564 organonitrogen compound metabolic process; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0005829 cytosol; GO:0044444 cytoplasmic part; ","GO:0016763 transferase activity, transferring pentosyl groups; GO:0004590 orotidine-5'-phosphate decarboxylase activity; GO:0003824 catalytic activity; GO:0016830 carbon-carbon lyase activity; GO:0016831 carboxy-lyase activity; GO:0016829 lyase activity; GO:0016757 transferase activity, transferring glycosyl groups; GO:0016740 transferase activity; GO:0004588 orotate phosphoribosyltransferase activity; ","K13421","UMPS; uridine monophosphate synthetase [EC:2.4.2.10 4.1.1.23]","hsa00983 Drug metabolism - other enzymes - Homo sapiens (human); hsa00240 Pyrimidine metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR013785; IPR000836; IPR004467; IPR011060; IPR001754; IPR029057; ","Aldolase-type TIM barrel; Phosphoribosyltransferase domain; Orotate phosphoribosyl transferase domain; Ribulose-phosphate binding barrel; Orotidine 5'-phosphate decarboxylase domain; Phosphoribosyltransferase-like; \r"]
["P11177","Pyruvate dehydrogenase E1 component subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=PDHB","PDHB",39.233,81.277,42.9,13,24,13,1.048,1.065,1.098,0.964,0.936,0.917,0.877,0.00278,"mitochondria\r","GO:0051188 cofactor biosynthetic process; GO:0019362 pyridine nucleotide metabolic process; GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0019216 regulation of lipid metabolic process; GO:0072524 pyridine-containing compound metabolic process; GO:0044237 cellular metabolic process; GO:0035384 thioester biosynthetic process; GO:0044272 sulfur compound biosynthetic process; GO:0006796 phosphate-containing compound metabolic process; GO:0006006 glucose metabolic process; GO:0006085 acetyl-CoA biosynthetic process; GO:0051196 regulation of coenzyme metabolic process; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0006753 nucleoside phosphate metabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0009108 coenzyme biosynthetic process; GO:0046487 glyoxylate metabolic process; GO:0006790 sulfur compound metabolic process; GO:0051193 regulation of cofactor metabolic process; GO:0072350 tricarboxylic acid metabolic process; GO:0051174 regulation of phosphorus metabolic process; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0071616 acyl-CoA biosynthetic process; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006081 cellular aldehyde metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0006732 coenzyme metabolic process; GO:0006084 acetyl-CoA metabolic process; GO:0005975 carbohydrate metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0051186 cofactor metabolic process; GO:0010565 regulation of cellular ketone metabolic process; GO:0006101 citrate metabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0050789 regulation of biological process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0019222 regulation of metabolic process; GO:0006082 organic acid metabolic process; GO:0042762 regulation of sulfur metabolic process; GO:0043436 oxoacid metabolic process; GO:0050794 regulation of cellular process; GO:0006725 cellular aromatic compound metabolic process; GO:0046496 nicotinamide nucleotide metabolic process; GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate; GO:0071704 organic substance metabolic process; GO:0006090 pyruvate metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0050812 regulation of acyl-CoA biosynthetic process; GO:0005996 monosaccharide metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0044711 single-organism biosynthetic process; GO:0006099 tricarboxylic acid cycle; GO:0035383 thioester metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0045333 cellular respiration; GO:0044249 cellular biosynthetic process; GO:0006637 acyl-CoA metabolic process; GO:0019217 regulation of fatty acid metabolic process; GO:0006793 phosphorus metabolic process; GO:0009060 aerobic respiration; GO:0019752 carboxylic acid metabolic process; GO:0019637 organophosphate metabolic process; GO:0006086 acetyl-CoA biosynthetic process from pyruvate; GO:0019318 hexose metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005759 mitochondrial matrix; GO:0044429 mitochondrial part; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0045254 pyruvate dehydrogenase complex; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:1990204 oxidoreductase complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0003824 catalytic activity; GO:0005488 binding; GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors; GO:0005515 protein binding; GO:0004738 pyruvate dehydrogenase activity; GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity; GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor; GO:0016491 oxidoreductase activity; ","K00162","PDHB; pyruvate dehydrogenase E1 component beta subunit [EC:1.2.4.1]","hsa00620 Pyruvate metabolism - Homo sapiens (human); hsa04066 HIF-1 signaling pathway - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00020 Citrate cycle (TCA cycle) - Homo sapiens (human); hsa04922 Glucagon signaling pathway - Homo sapiens (human); hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); hsa05230 Central carbon metabolism in cancer - Homo sapiens (human); ","IPR009014; IPR033248; IPR029061; IPR005475; ","\"Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II; Transketolase, C-terminal domain; Thiamin diphosphate-binding fold; Transketolase-like, pyrimidine-binding domain; \"\r"]
["P11215","Integrin alpha-M OS=Homo sapiens OX=9606 GN=ITGAM","ITGAM",127.18,24.972,4.6,5,8,5,0.873,0.918,0.874,1.028,1.159,1.136,1.247,0.00568,"extracellular\r","GO:0044700 single organism signaling; GO:0045321 leukocyte activation; GO:0051674 localization of cell; GO:0007166 cell surface receptor signaling pathway; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0031347 regulation of defense response; GO:0051234 establishment of localization; GO:0022610 biological adhesion; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0045088 regulation of innate immune response; GO:0007155 cell adhesion; GO:0002221 pattern recognition receptor signaling pathway; GO:0030198 extracellular matrix organization; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0009888 tissue development; GO:0002758 innate immune response-activating signal transduction; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0048870 cell motility; GO:0002764 immune response-regulating signaling pathway; GO:0007229 integrin-mediated signaling pathway; GO:0023052 signaling; GO:0002444 myeloid leukocyte mediated immunity; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0050900 leukocyte migration; GO:0050789 regulation of biological process; GO:0010668 ectodermal cell differentiation; GO:0002224 toll-like receptor signaling pathway; GO:0032940 secretion by cell; GO:0048583 regulation of response to stimulus; GO:0002682 regulation of immune system process; GO:0040011 locomotion; GO:0043299 leukocyte degranulation; GO:0048856 anatomical structure development; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0016477 cell migration; GO:0002283 neutrophil activation involved in immune response; GO:0002218 activation of innate immune response; GO:0002252 immune effector process; GO:0080134 regulation of response to stress; GO:0050896 response to stimulus; GO:0030154 cell differentiation; GO:0031349 positive regulation of defense response; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0043062 extracellular structure organization; GO:0007398 ectoderm development; GO:0002757 immune response-activating signal transduction; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0050778 positive regulation of immune response; GO:0002253 activation of immune response; GO:0045089 positive regulation of innate immune response; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0043312 neutrophil degranulation; GO:0002263 cell activation involved in immune response; GO:0048518 positive regulation of biological process; GO:0034142 toll-like receptor 4 signaling pathway; GO:0002366 leukocyte activation involved in immune response; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:0044767 single-organism developmental process; GO:0002684 positive regulation of immune system process; GO:0006928 movement of cell or subcellular component; GO:0001775 cell activation; GO:0051179 localization; GO:0006955 immune response; GO:0048584 positive regulation of response to stimulus; GO:0071840 cellular component organization or biogenesis; GO:0006887 exocytosis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0098636 protein complex involved in cell adhesion; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0070821 tertiary granule membrane; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0035579 specific granule membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0031226 intrinsic component of plasma membrane; GO:0098588 bounding membrane of organelle; GO:0098802 plasma membrane receptor complex; GO:0098797 plasma membrane protein complex; GO:0070820 tertiary granule; GO:0044446 intracellular organelle part; GO:0043235 receptor complex; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0008305 integrin complex; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0030667 secretory granule membrane; GO:0044459 plasma membrane part; GO:0042581 specific granule; GO:0009986 cell surface; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0097367 carbohydrate derivative binding; GO:0046982 protein heterodimerization activity; GO:0005488 binding; GO:0043167 ion binding; GO:0046983 protein dimerization activity; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0001948 glycoprotein binding; ","K06461","ITGAM; integrin alpha M","hsa05152 Tuberculosis - Homo sapiens (human); hsa04015 Rap1 signaling pathway - Homo sapiens (human); hsa05150 Staphylococcus aureus infection - Homo sapiens (human); hsa05221 Acute myeloid leukemia - Homo sapiens (human); hsa05140 Leishmaniasis - Homo sapiens (human); hsa04640 Hematopoietic cell lineage - Homo sapiens (human); hsa05146 Amoebiasis - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa05134 Legionellosis - Homo sapiens (human); hsa05133 Pertussis - Homo sapiens (human); hsa04610 Complement and coagulation cascades - Homo sapiens (human); hsa04670 Leukocyte transendothelial migration - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); hsa04514 Cell adhesion molecules (CAMs) - Homo sapiens (human); hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human); ","IPR032695; IPR013649; IPR002035; ","\"Integrin domain; Integrin alpha-2; von Willebrand factor, type A; \"\r"]
["P11216","Glycogen phosphorylase, brain form OS=Homo sapiens OX=9606 GN=PYGB","PYGB",96.695,323.31,53.1,45,106,35,1.114,1.093,1.092,0.925,0.885,0.907,0.824,1.76E-4,"cytoplasm\r","GO:0045321 leukocyte activation; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0044275 cellular carbohydrate catabolic process; GO:0044042 glucan metabolic process; GO:0044699 single-organism process; GO:0006112 energy reserve metabolic process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0044264 cellular polysaccharide metabolic process; GO:0051234 establishment of localization; GO:0071704 organic substance metabolic process; GO:0005980 glycogen catabolic process; GO:0008152 metabolic process; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0006091 generation of precursor metabolites and energy; GO:0044262 cellular carbohydrate metabolic process; GO:0005976 polysaccharide metabolic process; GO:0044248 cellular catabolic process; GO:0036230 granulocyte activation; GO:0043170 macromolecule metabolic process; GO:0009987 cellular process; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0002443 leukocyte mediated immunity; GO:0009251 glucan catabolic process; GO:0044724 single-organism carbohydrate catabolic process; GO:0006073 cellular glucan metabolic process; GO:0044712 single-organism catabolic process; GO:0055114 oxidation-reduction process; GO:0044247 cellular polysaccharide catabolic process; GO:0002446 neutrophil mediated immunity; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0005977 glycogen metabolic process; GO:0002376 immune system process; GO:0000272 polysaccharide catabolic process; GO:0043312 neutrophil degranulation; GO:0044238 primary metabolic process; GO:0005975 carbohydrate metabolic process; GO:0002263 cell activation involved in immune response; GO:0002444 myeloid leukocyte mediated immunity; GO:0016052 carbohydrate catabolic process; GO:0006810 transport; GO:0002366 leukocyte activation involved in immune response; GO:1901575 organic substance catabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:0032940 secretion by cell; GO:0044710 single-organism metabolic process; GO:0009057 macromolecule catabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0044260 cellular macromolecule metabolic process; GO:0001775 cell activation; GO:0043299 leukocyte degranulation; GO:0051179 localization; GO:0006955 immune response; GO:0009056 catabolic process; GO:0006887 exocytosis; ","GO:0034774 secretory granule lumen; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0042582 azurophil granule; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0016758 transferase activity, transferring hexosyl groups; GO:0003824 catalytic activity; GO:0005488 binding; GO:0004645 phosphorylase activity; GO:0043167 ion binding; GO:0016757 transferase activity, transferring glycosyl groups; GO:0005515 protein binding; GO:0043168 anion binding; GO:0016740 transferase activity; GO:0048037 cofactor binding; GO:0008184 glycogen phosphorylase activity; GO:0030170 pyridoxal phosphate binding; ","K00688","PYG; glycogen phosphorylase [EC:2.4.1.1]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00500 Starch and sucrose metabolism - Homo sapiens (human); hsa04922 Glucagon signaling pathway - Homo sapiens (human); hsa04910 Insulin signaling pathway - Homo sapiens (human); hsa04217 Necroptosis - Homo sapiens (human); hsa04931 Insulin resistance - Homo sapiens (human); "]
["P11217","Glycogen phosphorylase, muscle form OS=Homo sapiens OX=9606 GN=PYGM","PYGM",97.091,14.607,16.9,14,26,3,0.794,0.808,1.067,1.213,1.108,1.07,1.271,0.0737,"cytoplasm\r","GO:0044275 cellular carbohydrate catabolic process; GO:0044042 glucan metabolic process; GO:0044699 single-organism process; GO:0006112 energy reserve metabolic process; GO:0044237 cellular metabolic process; GO:0044264 cellular polysaccharide metabolic process; GO:0071704 organic substance metabolic process; GO:0005980 glycogen catabolic process; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0044262 cellular carbohydrate metabolic process; GO:0005976 polysaccharide metabolic process; GO:0044248 cellular catabolic process; GO:0043170 macromolecule metabolic process; GO:0009987 cellular process; GO:0044724 single-organism carbohydrate catabolic process; GO:0009251 glucan catabolic process; GO:0006073 cellular glucan metabolic process; GO:0044712 single-organism catabolic process; GO:0055114 oxidation-reduction process; GO:0044247 cellular polysaccharide catabolic process; GO:0044763 single-organism cellular process; GO:0005977 glycogen metabolic process; GO:0005975 carbohydrate metabolic process; GO:0044238 primary metabolic process; GO:0000272 polysaccharide catabolic process; GO:0016052 carbohydrate catabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:1901575 organic substance catabolic process; GO:0044710 single-organism metabolic process; GO:0009057 macromolecule catabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0044260 cellular macromolecule metabolic process; GO:0009056 catabolic process; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0016758 transferase activity, transferring hexosyl groups; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0048037 cofactor binding; GO:0030170 pyridoxal phosphate binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0004645 phosphorylase activity; GO:0016757 transferase activity, transferring glycosyl groups; GO:0043168 anion binding; GO:0016740 transferase activity; GO:0008184 glycogen phosphorylase activity; GO:0036094 small molecule binding; ","K00688","PYG; glycogen phosphorylase [EC:2.4.1.1]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00500 Starch and sucrose metabolism - Homo sapiens (human); hsa04922 Glucagon signaling pathway - Homo sapiens (human); hsa04910 Insulin signaling pathway - Homo sapiens (human); hsa04217 Necroptosis - Homo sapiens (human); hsa04931 Insulin resistance - Homo sapiens (human); "]
["P11233","Ras-related protein Ral-A OS=Homo sapiens OX=9606 GN=RALA","RALA",23.567,29.233,23.8,5,7,3,1.074,1.081,1.037,0.873,0.977,0.973,0.884,0.0337,"cytoplasm\r","GO:0001841 neural tube formation; GO:0044700 single organism signaling; GO:0060627 regulation of vesicle-mediated transport; GO:0060491 regulation of cell projection assembly; GO:0035148 tube formation; GO:0043009 chordate embryonic development; GO:0044699 single-organism process; GO:0051046 regulation of secretion; GO:0044764 multi-organism cellular process; GO:0051668 localization within membrane; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0009605 response to external stimulus; GO:0030036 actin cytoskeleton organization; GO:0048729 tissue morphogenesis; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0032879 regulation of localization; GO:0009790 embryo development; GO:0044419 interspecies interaction between organisms; GO:0048598 embryonic morphogenesis; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0035295 tube development; GO:0051716 cellular response to stimulus; GO:0009888 tissue development; GO:0031346 positive regulation of cell projection organization; GO:0035239 tube morphogenesis; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0007264 small GTPase mediated signal transduction; GO:1903530 regulation of secretion by cell; GO:0023052 signaling; GO:0006935 chemotaxis; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0031532 actin cytoskeleton reorganization; GO:1902589 single-organism organelle organization; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032940 secretion by cell; GO:0042330 taxis; GO:0040011 locomotion; GO:0051301 cell division; GO:0048856 anatomical structure development; GO:0007265 Ras protein signal transduction; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0002009 morphogenesis of an epithelium; GO:0044707 single-multicellular organism process; GO:0017157 regulation of exocytosis; GO:0031344 regulation of cell projection organization; GO:0044087 regulation of cellular component biogenesis; GO:0050896 response to stimulus; GO:0021915 neural tube development; GO:0051489 regulation of filopodium assembly; GO:0072175 epithelial tube formation; GO:0009653 anatomical structure morphogenesis; GO:0060606 tube closure; GO:1902578 single-organism localization; GO:0000910 cytokinesis; GO:0016032 viral process; GO:0016331 morphogenesis of embryonic epithelium; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0001843 neural tube closure; GO:0051665 membrane raft localization; GO:0060562 epithelial tube morphogenesis; GO:0035556 intracellular signal transduction; GO:0051049 regulation of transport; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0009792 embryo development ending in birth or egg hatching; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0001838 embryonic epithelial tube formation; GO:0014020 primary neural tube formation; GO:0051491 positive regulation of filopodium assembly; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0061024 membrane organization; GO:0030029 actin filament-based process; GO:0051128 regulation of cellular component organization; GO:0022402 cell cycle process; GO:0051179 localization; GO:0044089 positive regulation of cellular component biogenesis; GO:0007049 cell cycle; GO:0006887 exocytosis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0032155 cell division site part; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0043209 myelin sheath; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0005912 adherens junction; GO:0030055 cell-substrate junction; GO:0032154 cleavage furrow; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0097610 cell surface furrow; GO:0032153 cell division site; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0030496 midbody; GO:0012506 vesicle membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0009986 cell surface; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0031625 ubiquitin protein ligase binding; GO:0005102 receptor binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0008092 cytoskeletal protein binding; GO:0016462 pyrophosphatase activity; GO:0019003 GDP binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0003924 GTPase activity; GO:0032550 purine ribonucleoside binding; GO:0001664 G-protein coupled receptor binding; GO:0043168 anion binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0017076 purine nucleotide binding; GO:0051117 ATPase binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0031755 Edg-2 lysophosphatidic acid receptor binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0031753 endothelial differentiation G-protein coupled receptor binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0032561 guanyl ribonucleotide binding; GO:0017022 myosin binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0019899 enzyme binding; GO:0036094 small molecule binding; ","K07834","RALA; Ras-related protein Ral-A","hsa04072 Phospholipase D signaling pathway - Homo sapiens (human); hsa04015 Rap1 signaling pathway - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa05210 Colorectal cancer - Homo sapiens (human); hsa04014 Ras signaling pathway - Homo sapiens (human); hsa05212 Pancreatic cancer - Homo sapiens (human); ","IPR005225; IPR027417; ","Small GTP-binding protein domain; P-loop containing nucleoside triphosphate hydrolase; \r"]
["P11234","Ras-related protein Ral-B OS=Homo sapiens OX=9606 GN=RALB","RALB",23.408,12.777,20.4,5,7,3,0.904,1.016,1.047,1.013,0.965,1.058,1.023,0.666,"cytoplasm\r","GO:0060627 regulation of vesicle-mediated transport; GO:0044700 single organism signaling; GO:0032270 positive regulation of cellular protein metabolic process; GO:0031331 positive regulation of cellular catabolic process; GO:0032092 positive regulation of protein binding; GO:0051046 regulation of secretion; GO:0044699 single-organism process; GO:0032091 negative regulation of protein binding; GO:0060178 regulation of exocyst localization; GO:1902115 regulation of organelle assembly; GO:0051130 positive regulation of cellular component organization; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0009605 response to external stimulus; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0032879 regulation of localization; GO:0006915 apoptotic process; GO:0044093 positive regulation of molecular function; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0051347 positive regulation of transferase activity; GO:0033674 positive regulation of kinase activity; GO:0051099 positive regulation of binding; GO:0070887 cellular response to chemical stimulus; GO:0014070 response to organic cyclic compound; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0044088 regulation of vacuole organization; GO:0051174 regulation of phosphorus metabolic process; GO:0045937 positive regulation of phosphate metabolic process; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0051098 regulation of binding; GO:0043331 response to dsRNA; GO:0048522 positive regulation of cellular process; GO:0007264 small GTPase mediated signal transduction; GO:1903530 regulation of secretion by cell; GO:0023052 signaling; GO:0031323 regulation of cellular metabolic process; GO:0010506 regulation of autophagy; GO:0016241 regulation of macroautophagy; GO:2000785 regulation of autophagosome assembly; GO:0043254 regulation of protein complex assembly; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0010638 positive regulation of organelle organization; GO:1901699 cellular response to nitrogen compound; GO:0051100 negative regulation of binding; GO:0010508 positive regulation of autophagy; GO:1902117 positive regulation of organelle assembly; GO:0050790 regulation of catalytic activity; GO:1901698 response to nitrogen compound; GO:0016239 positive regulation of macroautophagy; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0051301 cell division; GO:0019220 regulation of phosphate metabolic process; GO:0007265 Ras protein signal transduction; GO:2000786 positive regulation of autophagosome assembly; GO:0043549 regulation of kinase activity; GO:0045859 regulation of protein kinase activity; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0009267 cellular response to starvation; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0031399 regulation of protein modification process; GO:0017157 regulation of exocytosis; GO:0044087 regulation of cellular component biogenesis; GO:0071902 positive regulation of protein serine/threonine kinase activity; GO:0050896 response to stimulus; GO:0031669 cellular response to nutrient levels; GO:0060341 regulation of cellular localization; GO:0043393 regulation of protein binding; GO:0009991 response to extracellular stimulus; GO:0000910 cytokinesis; GO:0009896 positive regulation of catabolic process; GO:0051338 regulation of transferase activity; GO:0032880 regulation of protein localization; GO:0009987 cellular process; GO:0071359 cellular response to dsRNA; GO:0006950 response to stress; GO:0043330 response to exogenous dsRNA; GO:0035556 intracellular signal transduction; GO:0051049 regulation of transport; GO:0001932 regulation of protein phosphorylation; GO:0033043 regulation of organelle organization; GO:0031401 positive regulation of protein modification process; GO:0071407 cellular response to organic cyclic compound; GO:0071496 cellular response to external stimulus; GO:0010033 response to organic substance; GO:0001934 positive regulation of protein phosphorylation; GO:0045860 positive regulation of protein kinase activity; GO:0048518 positive regulation of biological process; GO:0031668 cellular response to extracellular stimulus; GO:0043085 positive regulation of catalytic activity; GO:0051247 positive regulation of protein metabolic process; GO:0071360 cellular response to exogenous dsRNA; GO:0008219 cell death; GO:0051246 regulation of protein metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0044090 positive regulation of vacuole organization; GO:0042594 response to starvation; GO:0051128 regulation of cellular component organization; GO:0012501 programmed cell death; GO:0022402 cell cycle process; GO:0031667 response to nutrient levels; GO:0001928 regulation of exocyst assembly; GO:0044089 positive regulation of cellular component biogenesis; GO:0007049 cell cycle; GO:1903827 regulation of cellular protein localization; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0030496 midbody; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:1901265 nucleoside phosphate binding; GO:0031625 ubiquitin protein ligase binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0019003 GDP binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0003924 GTPase activity; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0017076 purine nucleotide binding; GO:0051117 ATPase binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0032561 guanyl ribonucleotide binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0019899 enzyme binding; GO:0036094 small molecule binding; ","K07835","RALB; Ras-related protein Ral-B","hsa04072 Phospholipase D signaling pathway - Homo sapiens (human); hsa04015 Rap1 signaling pathway - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa05210 Colorectal cancer - Homo sapiens (human); hsa04014 Ras signaling pathway - Homo sapiens (human); hsa05212 Pancreatic cancer - Homo sapiens (human); ","IPR005225; IPR027417; ","Small GTP-binding protein domain; P-loop containing nucleoside triphosphate hydrolase; \r"]
["P11277","Spectrin beta chain, erythrocytic OS=Homo sapiens OX=9606 GN=SPTB","SPTB",246.47,323.31,37.6,72,116,66,0.863,0.863,0.903,1.132,1.1,1.125,1.277,1.45E-4,"nucleus\r","GO:0044700 single organism signaling; GO:0030833 regulation of actin filament polymerization; GO:0065008 regulation of biological quality; GO:0030835 negative regulation of actin filament depolymerization; GO:0051129 negative regulation of cellular component organization; GO:0048869 cellular developmental process; GO:0048666 neuron development; GO:0044699 single-organism process; GO:0032989 cellular component morphogenesis; GO:0022008 neurogenesis; GO:0030832 regulation of actin filament length; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0051693 actin filament capping; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0032990 cell part morphogenesis; GO:0032535 regulation of cellular component size; GO:0044093 positive regulation of molecular function; GO:0032271 regulation of protein polymerization; GO:0048858 cell projection morphogenesis; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0051493 regulation of cytoskeleton organization; GO:0031333 negative regulation of protein complex assembly; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0048699 generation of neurons; GO:0051494 negative regulation of cytoskeleton organization; GO:0044763 single-organism cellular process; GO:0048812 neuron projection morphogenesis; GO:0023052 signaling; GO:0006935 chemotaxis; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:0000902 cell morphogenesis; GO:0000165 MAPK cascade; GO:0010639 negative regulation of organelle organization; GO:0050789 regulation of biological process; GO:0043254 regulation of protein complex assembly; GO:0042221 response to chemical; GO:0051336 regulation of hydrolase activity; GO:0030030 cell projection organization; GO:0044710 single-organism metabolic process; GO:0043242 negative regulation of protein complex disassembly; GO:0050790 regulation of catalytic activity; GO:0044260 cellular macromolecule metabolic process; GO:1902904 negative regulation of supramolecular fiber organization; GO:0065009 regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0006464 cellular protein modification process; GO:0030837 negative regulation of actin filament polymerization; GO:0042330 taxis; GO:0043244 regulation of protein complex disassembly; GO:0030834 regulation of actin filament depolymerization; GO:0040011 locomotion; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:1902903 regulation of supramolecular fiber organization; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0016310 phosphorylation; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0032956 regulation of actin cytoskeleton organization; GO:0044267 cellular protein metabolic process; GO:0048193 Golgi vesicle transport; GO:0044087 regulation of cellular component biogenesis; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0007411 axon guidance; GO:0071704 organic substance metabolic process; GO:0000904 cell morphogenesis involved in differentiation; GO:1901880 negative regulation of protein depolymerization; GO:0009653 anatomical structure morphogenesis; GO:0030154 cell differentiation; GO:0006468 protein phosphorylation; GO:0051345 positive regulation of hydrolase activity; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0007409 axonogenesis; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0023014 signal transduction by protein phosphorylation; GO:0035556 intracellular signal transduction; GO:0043547 positive regulation of GTPase activity; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:1901879 regulation of protein depolymerization; GO:0033043 regulation of organelle organization; GO:0032970 regulation of actin filament-based process; GO:0044238 primary metabolic process; GO:0031175 neuron projection development; GO:0051641 cellular localization; GO:0043085 positive regulation of catalytic activity; GO:0008064 regulation of actin polymerization or depolymerization; GO:0061564 axon development; GO:0030182 neuron differentiation; GO:0006793 phosphorus metabolic process; GO:0097485 neuron projection guidance; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0090066 regulation of anatomical structure size; GO:0006928 movement of cell or subcellular component; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0043412 macromolecule modification; GO:0032272 negative regulation of protein polymerization; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0005938 cell cortex; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0099568 cytoplasmic region; GO:0030863 cortical cytoskeleton; GO:0031224 intrinsic component of membrane; GO:0032991 macromolecular complex; GO:0030864 cortical actin cytoskeleton; GO:0044424 intracellular part; GO:0005623 cell; GO:0009898 cytoplasmic side of plasma membrane; GO:0098562 cytoplasmic side of membrane; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0008091 spectrin; GO:0043227 membrane-bounded organelle; GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane; GO:0098552 side of membrane; GO:0043229 intracellular organelle; GO:0031226 intrinsic component of plasma membrane; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0015629 actin cytoskeleton; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044459 plasma membrane part; GO:0044448 cell cortex part; GO:0009986 cell surface; GO:0043234 protein complex; GO:0005794 Golgi apparatus; GO:0014731 spectrin-associated cytoskeleton; GO:0044444 cytoplasmic part; ","GO:0051015 actin filament binding; GO:0008092 cytoskeletal protein binding; GO:0005085 guanyl-nucleotide exchange factor activity; GO:0005200 structural constituent of cytoskeleton; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0003779 actin binding; GO:0005088 Ras guanyl-nucleotide exchange factor activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0005198 structural molecule activity; GO:0030506 ankyrin binding; GO:0032403 protein complex binding; ","K06115",null,null,"IPR001715; ","Calponin homology domain; \r"]
["P11279","Lysosome-associated membrane glycoprotein 1 OS=Homo sapiens OX=9606 GN=LAMP1","LAMP1",44.882,47.859,10.3,4,7,4,0.988,1.057,1.098,0.911,0.966,1.004,0.917,0.106,"extracellular\r","GO:0044409 entry into host; GO:0060627 regulation of vesicle-mediated transport; GO:0044700 single organism signaling; GO:0002694 regulation of leukocyte activation; GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0031347 regulation of defense response; GO:0031343 positive regulation of cell killing; GO:0032879 regulation of localization; GO:0043321 regulation of natural killer cell degranulation; GO:0033365 protein localization to organelle; GO:0044419 interspecies interaction between organisms; GO:0008104 protein localization; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0046718 viral entry into host cell; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0045921 positive regulation of exocytosis; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0002717 positive regulation of natural killer cell mediated immunity; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0032886 regulation of microtubule-based process; GO:0006810 transport; GO:0048583 regulation of response to stimulus; GO:0002682 regulation of immune system process; GO:0051047 positive regulation of secretion; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0032814 regulation of natural killer cell activation; GO:0002283 neutrophil activation involved in immune response; GO:0090160 Golgi to lysosome transport; GO:0097190 apoptotic signaling pathway; GO:0051806 entry into cell of other organism involved in symbiotic interaction; GO:0008626 granzyme-mediated apoptotic signaling pathway; GO:0017157 regulation of exocytosis; GO:0002715 regulation of natural killer cell mediated immunity; GO:0080134 regulation of response to stress; GO:0060341 regulation of cellular localization; GO:0050867 positive regulation of cell activation; GO:0031349 positive regulation of defense response; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0060632 regulation of microtubule-based movement; GO:0043300 regulation of leukocyte degranulation; GO:0034613 cellular protein localization; GO:0050778 positive regulation of immune response; GO:1902513 regulation of organelle transport along microtubule; GO:0006896 Golgi to vacuole transport; GO:0051270 regulation of cellular component movement; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0002263 cell activation involved in immune response; GO:0048102 autophagic cell death; GO:0045184 establishment of protein localization; GO:0002696 positive regulation of leukocyte activation; GO:0045055 regulated exocytosis; GO:0001775 cell activation; GO:0031647 regulation of protein stability; GO:0012501 programmed cell death; GO:0006955 immune response; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0006892 post-Golgi vesicle-mediated transport; GO:0050821 protein stabilization; GO:0006887 exocytosis; GO:0072594 establishment of protein localization to organelle; GO:0044699 single-organism process; GO:0051046 regulation of secretion; GO:0044764 multi-organism cellular process; GO:0051249 regulation of lymphocyte activation; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0045088 regulation of innate immune response; GO:1903307 positive regulation of regulated secretory pathway; GO:0006915 apoptotic process; GO:0033036 macromolecule localization; GO:0002697 regulation of immune effector process; GO:0002708 positive regulation of lymphocyte mediated immunity; GO:0002274 myeloid leukocyte activation; GO:0002446 neutrophil mediated immunity; GO:0048522 positive regulation of cellular process; GO:0051251 positive regulation of lymphocyte activation; GO:0032386 regulation of intracellular transport; GO:0023052 signaling; GO:1903530 regulation of secretion by cell; GO:0045954 positive regulation of natural killer cell mediated cytotoxicity; GO:0002444 myeloid leukocyte mediated immunity; GO:0051050 positive regulation of transport; GO:0030260 entry into host cell; GO:0050789 regulation of biological process; GO:0050865 regulation of cell activation; GO:1903532 positive regulation of secretion by cell; GO:0002705 positive regulation of leukocyte mediated immunity; GO:0032940 secretion by cell; GO:0051828 entry into other organism involved in symbiotic interaction; GO:0042269 regulation of natural killer cell mediated cytotoxicity; GO:0043299 leukocyte degranulation; GO:0043302 positive regulation of leukocyte degranulation; GO:0002252 immune effector process; GO:0031341 regulation of cell killing; GO:0019058 viral life cycle; GO:0048193 Golgi vesicle transport; GO:0032816 positive regulation of natural killer cell activation; GO:0050896 response to stimulus; GO:0002706 regulation of lymphocyte mediated immunity; GO:0001912 positive regulation of leukocyte mediated cytotoxicity; GO:0016032 viral process; GO:0043323 positive regulation of natural killer cell degranulation; GO:0036230 granulocyte activation; GO:0016482 cytosolic transport; GO:0009987 cellular process; GO:0007041 lysosomal transport; GO:0045089 positive regulation of innate immune response; GO:0001910 regulation of leukocyte mediated cytotoxicity; GO:0051049 regulation of transport; GO:0002699 positive regulation of immune effector process; GO:1903305 regulation of regulated secretory pathway; GO:0051701 interaction with host; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0002703 regulation of leukocyte mediated immunity; GO:0002366 leukocyte activation involved in immune response; GO:0070727 cellular macromolecule localization; GO:0042119 neutrophil activation; GO:0008219 cell death; GO:0007034 vacuolar transport; GO:0002684 positive regulation of immune system process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0030425 dendrite; GO:0044421 extracellular region part; GO:0009897 external side of plasma membrane; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0043025 neuronal cell body; GO:0044754 autolysosome; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0070382 exocytic vesicle; GO:0005765 lysosomal membrane; GO:0070062 extracellular exosome; GO:0008021 synaptic vesicle; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:0043005 neuron projection; GO:0005767 secondary lysosome; GO:0043227 membrane-bounded organelle; GO:0005771 multivesicular body; GO:0097458 neuron part; GO:0000323 lytic vacuole; GO:0098552 side of membrane; GO:0010008 endosome membrane; GO:0031226 intrinsic component of plasma membrane; GO:0042995 cell projection; GO:0005770 late endosome; GO:0030666 endocytic vesicle membrane; GO:0035577 azurophil granule membrane; GO:0044440 endosomal part; GO:0012506 vesicle membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0042582 azurophil granule; GO:0043231 intracellular membrane-bounded organelle; GO:0030667 secretory granule membrane; GO:0101003 ficolin-1-rich granule membrane; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0030133 transport vesicle; GO:0042383 sarcolemma; GO:0043230 extracellular organelle; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0044194 cytolytic granule; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0042599 lamellar body; GO:0048770 pigment granule; GO:0005776 autophagosome; GO:0032010 phagolysosome; GO:0044425 membrane part; GO:0044464 cell part; GO:0098793 presynapse; GO:0061474 phagolysosome membrane; GO:0030670 phagocytic vesicle membrane; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0005768 endosome; GO:0030141 secretory granule; GO:0030139 endocytic vesicle; GO:0044456 synapse part; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0042470 melanosome; GO:0070820 tertiary granule; GO:0044446 intracellular organelle part; GO:0045335 phagocytic vesicle; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0016021 integral component of membrane; GO:0045202 synapse; GO:0030659 cytoplasmic vesicle membrane; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0044459 plasma membrane part; GO:0097208 alveolar lamellar body; GO:0005774 vacuolar membrane; GO:0044297 cell body; GO:0009986 cell surface; GO:0044444 cytoplasmic part; ","GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0005488 binding; GO:0005515 protein binding; GO:0019904 protein domain specific binding; GO:0001618 virus receptor activity; GO:0019899 enzyme binding; ","K06528","LAMP1_2; lysosomal-associated membrane protein 1/2","hsa04142 Lysosome - Homo sapiens (human); hsa05152 Tuberculosis - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); hsa04140 Autophagy - animal - Homo sapiens (human); "]
["P11310","Medium-chain specific acyl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ACADM","ACADM",46.588,29.888,19.2,8,11,8,1.231,1.258,1.196,0.792,0.776,0.751,0.629,2.32e-05,"mitochondria\r","GO:0034440 lipid oxidation; GO:0051793 medium-chain fatty acid catabolic process; GO:0097164 ammonium ion metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044255 cellular lipid metabolic process; GO:0045329 carnitine biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0030258 lipid modification; GO:0044248 cellular catabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0051791 medium-chain fatty acid metabolic process; GO:0009987 cellular process; GO:0006629 lipid metabolic process; GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase; GO:0016042 lipid catabolic process; GO:0019395 fatty acid oxidation; GO:0055114 oxidation-reduction process; GO:0044712 single-organism catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006578 amino-acid betaine biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0006635 fatty acid beta-oxidation; GO:0072329 monocarboxylic acid catabolic process; GO:0044282 small molecule catabolic process; GO:0006631 fatty acid metabolic process; GO:0044238 primary metabolic process; GO:0006577 amino-acid betaine metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0046395 carboxylic acid catabolic process; GO:1901575 organic substance catabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0044710 single-organism metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0016054 organic acid catabolic process; GO:0044242 cellular lipid catabolic process; GO:0009437 carnitine metabolic process; GO:0006082 organic acid metabolic process; GO:0019254 carnitine metabolic process, CoA-linked; GO:0009056 catabolic process; GO:0009062 fatty acid catabolic process; GO:0043436 oxoacid metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005759 mitochondrial matrix; GO:0042995 cell projection; GO:0044429 mitochondrial part; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0030424 axon; GO:0005634 nucleus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0050660 flavin adenine dinucleotide binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0048037 cofactor binding; GO:0016491 oxidoreductase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043168 anion binding; GO:0070991 medium-chain-acyl-CoA dehydrogenase activity; GO:0003995 acyl-CoA dehydrogenase activity; GO:0050662 coenzyme binding; GO:0036094 small molecule binding; ","K00249","ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7]","hsa00280 Valine, leucine and isoleucine degradation - Homo sapiens (human); hsa03320 PPAR signaling pathway - Homo sapiens (human); hsa00640 Propanoate metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa01212 Fatty acid metabolism - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); hsa00071 Fatty acid degradation - Homo sapiens (human); hsa00410 beta-Alanine metabolism - Homo sapiens (human); ","IPR013786; IPR009100; IPR006091; IPR009075; ","\"Acyl-CoA dehydrogenase/oxidase, N-terminal; Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain; Acyl-CoA oxidase/dehydrogenase, central domain; Acyl-CoA dehydrogenase/oxidase C-terminal; \"\r"]
["P11413","Glucose-6-phosphate 1-dehydrogenase OS=Homo sapiens OX=9606 GN=G6PD","G6PD",59.256,89.047,35.9,20,33,20,1.009,1.014,1.004,0.979,0.978,0.974,0.968,0.000584,"cytoplasm\r","GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel; GO:0021700 developmental maturation; GO:0065008 regulation of biological quality; GO:0010941 regulation of cell death; GO:0006518 peptide metabolic process; GO:0019362 pyridine nucleotide metabolic process; GO:0006066 alcohol metabolic process; GO:0002262 myeloid cell homeostasis; GO:0007420 brain development; GO:0043523 regulation of neuron apoptotic process; GO:1901862 negative regulation of muscle tissue development; GO:0051154 negative regulation of striated muscle cell differentiation; GO:0044237 cellular metabolic process; GO:1904427 positive regulation of calcium ion transmembrane transport; GO:0008610 lipid biosynthetic process; GO:0010732 regulation of protein glutathionylation; GO:0048857 neural nucleus development; GO:0006006 glucose metabolic process; GO:0001558 regulation of cell growth; GO:0009605 response to external stimulus; GO:0021762 substantia nigra development; GO:0046390 ribose phosphate biosynthetic process; GO:0061050 regulation of cell growth involved in cardiac muscle cell development; GO:0008152 metabolic process; GO:0014743 regulation of muscle hypertrophy; GO:1901137 carbohydrate derivative biosynthetic process; GO:0061515 myeloid cell development; GO:0045843 negative regulation of striated muscle tissue development; GO:0032879 regulation of localization; GO:0044057 regulation of system process; GO:0006098 pentose-phosphate shunt; GO:0019693 ribose phosphate metabolic process; GO:0019321 pentose metabolic process; GO:0051147 regulation of muscle cell differentiation; GO:0006790 sulfur compound metabolic process; GO:0007399 nervous system development; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0030901 midbrain development; GO:0080090 regulation of primary metabolic process; GO:0044281 small molecule metabolic process; GO:0008202 steroid metabolic process; GO:0043269 regulation of ion transport; GO:0044763 single-organism cellular process; GO:0048821 erythrocyte development; GO:0006081 cellular aldehyde metabolic process; GO:1901617 organic hydroxy compound biosynthetic process; GO:0002520 immune system development; GO:0006732 coenzyme metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0005975 carbohydrate metabolic process; GO:0032501 multicellular organismal process; GO:0048872 homeostasis of number of cells; GO:0090407 organophosphate biosynthetic process; GO:0034762 regulation of transmembrane transport; GO:0048635 negative regulation of muscle organ development; GO:0048513 animal organ development; GO:0032269 negative regulation of cellular protein metabolic process; GO:0007417 central nervous system development; GO:0044710 single-organism metabolic process; GO:0030218 erythrocyte differentiation; GO:0048583 regulation of response to stimulus; GO:0010721 negative regulation of cell development; GO:1901362 organic cyclic compound biosynthetic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0044707 single-multicellular organism process; GO:0034764 positive regulation of transmembrane transport; GO:1901615 organic hydroxy compound metabolic process; GO:0046496 nicotinamide nucleotide metabolic process; GO:0031399 regulation of protein modification process; GO:1902653 secondary alcohol biosynthetic process; GO:0043067 regulation of programmed cell death; GO:1901700 response to oxygen-containing compound; GO:0046364 monosaccharide biosynthetic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0016125 sterol metabolic process; GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development; GO:0055022 negative regulation of cardiac muscle tissue growth; GO:0051239 regulation of multicellular organismal process; GO:1905208 negative regulation of cardiocyte differentiation; GO:0016126 sterol biosynthetic process; GO:0051156 glucose 6-phosphate metabolic process; GO:0046483 heterocycle metabolic process; GO:0010039 response to iron ion; GO:0006139 nucleobase-containing compound metabolic process; GO:0010959 regulation of metal ion transport; GO:1901135 carbohydrate derivative metabolic process; GO:2000378 negative regulation of reactive oxygen species metabolic process; GO:0007275 multicellular organism development; GO:1904062 regulation of cation transmembrane transport; GO:0010734 negative regulation of protein glutathionylation; GO:0051928 positive regulation of calcium ion transport; GO:0008203 cholesterol metabolic process; GO:0032094 response to food; GO:0006950 response to stress; GO:0044711 single-organism biosynthetic process; GO:0048731 system development; GO:0060284 regulation of cell development; GO:0046165 alcohol biosynthetic process; GO:0051924 regulation of calcium ion transport; GO:0002376 immune system process; GO:0097305 response to alcohol; GO:0046621 negative regulation of organ growth; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0010611 regulation of cardiac muscle hypertrophy; GO:0006694 steroid biosynthetic process; GO:0043270 positive regulation of ion transport; GO:0043502 regulation of muscle adaptation; GO:1904064 positive regulation of cation transmembrane transport; GO:0006793 phosphorus metabolic process; GO:0044283 small molecule biosynthetic process; GO:0019637 organophosphate metabolic process; GO:2000726 negative regulation of cardiac muscle cell differentiation; GO:0050793 regulation of developmental process; GO:0019318 hexose metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0046620 regulation of organ growth; GO:0006739 NADP metabolic process; GO:0055021 regulation of cardiac muscle tissue growth; GO:0051093 negative regulation of developmental process; GO:0048640 negative regulation of developmental growth; GO:0060420 regulation of heart growth; GO:0009051 pentose-phosphate shunt, oxidative branch; GO:0048869 cellular developmental process; GO:0009117 nucleotide metabolic process; GO:0048634 regulation of muscle organ development; GO:0044699 single-organism process; GO:0051241 negative regulation of multicellular organismal process; GO:2000725 regulation of cardiac muscle cell differentiation; GO:0009058 biosynthetic process; GO:0072524 pyridine-containing compound metabolic process; GO:0031400 negative regulation of protein modification process; GO:0006796 phosphate-containing compound metabolic process; GO:0034101 erythrocyte homeostasis; GO:0043249 erythrocyte maturation; GO:0006753 nucleoside phosphate metabolic process; GO:0006979 response to oxidative stress; GO:0048469 cell maturation; GO:0006749 glutathione metabolic process; GO:0060322 head development; GO:0034599 cellular response to oxidative stress; GO:0010035 response to inorganic substance; GO:0045596 negative regulation of cell differentiation; GO:0070887 cellular response to chemical stimulus; GO:0006629 lipid metabolic process; GO:0019322 pentose biosynthetic process; GO:0032502 developmental process; GO:0055024 regulation of cardiac muscle tissue development; GO:0045926 negative regulation of growth; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0055114 oxidation-reduction process; GO:1901360 organic cyclic compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0090257 regulation of muscle system process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0010038 response to metal ion; GO:0051050 positive regulation of transport; GO:0051186 cofactor metabolic process; GO:0030308 negative regulation of cell growth; GO:0044723 single-organism carbohydrate metabolic process; GO:0006740 NADPH regeneration; GO:0016202 regulation of striated muscle tissue development; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0061117 negative regulation of heart growth; GO:0034767 positive regulation of ion transmembrane transport; GO:0019222 regulation of metabolic process; GO:0051148 negative regulation of muscle cell differentiation; GO:2000377 regulation of reactive oxygen species metabolic process; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0016051 carbohydrate biosynthetic process; GO:0040008 regulation of growth; GO:0006725 cellular aromatic compound metabolic process; GO:1902652 secondary alcohol metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0045471 response to ethanol; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0048638 regulation of developmental growth; GO:0048468 cell development; GO:0071704 organic substance metabolic process; GO:0009991 response to extracellular stimulus; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:0010041 response to iron(III) ion; GO:0006575 cellular modified amino acid metabolic process; GO:0006695 cholesterol biosynthetic process; GO:0019682 glyceraldehyde-3-phosphate metabolic process; GO:1903169 regulation of calcium ion transmembrane transport; GO:0005996 monosaccharide metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:1901214 regulation of neuron death; GO:0055026 negative regulation of cardiac muscle tissue development; GO:0045595 regulation of cell differentiation; GO:0030099 myeloid cell differentiation; GO:0051049 regulation of transport; GO:1901861 regulation of muscle tissue development; GO:0006807 nitrogen compound metabolic process; GO:0014741 negative regulation of muscle hypertrophy; GO:0048518 positive regulation of biological process; GO:0048534 hematopoietic or lymphoid organ development; GO:0030097 hemopoiesis; GO:0051153 regulation of striated muscle cell differentiation; GO:0034765 regulation of ion transmembrane transport; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0010614 negative regulation of cardiac muscle hypertrophy; GO:0051248 negative regulation of protein metabolic process; GO:0031667 response to nutrient levels; GO:0051128 regulation of cellular component organization; GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel; GO:0042981 regulation of apoptotic process; GO:1905207 regulation of cardiocyte differentiation; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0009898 cytoplasmic side of plasma membrane; GO:0098562 cytoplasmic side of membrane; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0098552 side of membrane; ","GO:1901265 nucleoside phosphate binding; GO:0005536 glucose binding; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0048029 monosaccharide binding; GO:0048037 cofactor binding; GO:0016491 oxidoreductase activity; GO:0097159 organic cyclic compound binding; GO:0016614 oxidoreductase activity, acting on CH-OH group of donors; GO:1901363 heterocyclic compound binding; GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0042803 protein homodimerization activity; GO:0004345 glucose-6-phosphate dehydrogenase activity; GO:0050661 NADP binding; GO:0030246 carbohydrate binding; GO:0050662 coenzyme binding; GO:0036094 small molecule binding; ","K00036","G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]","hsa00480 Glutathione metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00030 Pentose phosphate pathway - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); hsa05230 Central carbon metabolism in cancer - Homo sapiens (human); ","IPR022675; IPR016040; IPR022674; ","\"Glucose-6-phosphate dehydrogenase, C-terminal; NAD(P)-binding domain; Glucose-6-phosphate dehydrogenase, NAD-binding; \"\r"]
["P11441","Ubiquitin-like protein 4A OS=Homo sapiens OX=9606 GN=UBL4A","UBL4A",17.776,13.701,15.9,2,2,2,1.133,1.186,1.014,0.943,0.811,0.941,0.809,0.0356,"cytoplasm\r","GO:0016043 cellular component organization; GO:0010256 endomembrane system organization; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0033365 protein localization to organelle; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0034613 cellular protein localization; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0090150 establishment of protein localization to membrane; GO:0009987 cellular process; GO:0051205 protein insertion into membrane; GO:0072657 protein localization to membrane; GO:0045048 protein insertion into ER membrane; GO:0044763 single-organism cellular process; GO:0044802 single-organism membrane organization; GO:0044238 primary metabolic process; GO:0051641 cellular localization; GO:0006810 transport; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:0051179 localization; GO:0071816 tail-anchored membrane protein insertion into ER membrane; GO:0071840 cellular component organization or biogenesis; GO:0007029 endoplasmic reticulum organization; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0072379 ER membrane insertion complex; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:0071818 BAT3 complex; GO:0044445 cytosolic part; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0019787 ubiquitin-like protein transferase activity; GO:0051087 chaperone binding; GO:0003824 catalytic activity; GO:0016740 transferase activity; GO:0005488 binding; ",{"$nulls":3},"IPR029071; IPR000626; ","Ubiquitin-related domain; Ubiquitin domain; \r"]
["P11532","Dystrophin OS=Homo sapiens OX=9606 GN=DMD","DMD",426.74,17.864,2.1,7,8,5,0.998,1.079,0.92,1.064,0.865,1.088,1.007,0.969,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0006518 peptide metabolic process; GO:0060271 cilium assembly; GO:0044237 cellular metabolic process; GO:0044782 cilium organization; GO:0010469 regulation of receptor activity; GO:0016203 muscle attachment; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0065003 macromolecular complex assembly; GO:0032879 regulation of localization; GO:1901019 regulation of calcium ion transmembrane transporter activity; GO:0044093 positive regulation of molecular function; GO:0032414 positive regulation of ion transmembrane transporter activity; GO:0044057 regulation of system process; GO:0008104 protein localization; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:0031346 positive regulation of cell projection organization; GO:0048699 generation of neurons; GO:0043269 regulation of ion transport; GO:0044763 single-organism cellular process; GO:0006941 striated muscle contraction; GO:2000649 regulation of sodium ion transmembrane transporter activity; GO:0090287 regulation of cellular response to growth factor stimulus; GO:0019932 second-messenger-mediated signaling; GO:0031323 regulation of cellular metabolic process; GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; GO:0060538 skeletal muscle organ development; GO:0032501 multicellular organismal process; GO:0034762 regulation of transmembrane transport; GO:0048513 animal organ development; GO:0055002 striated muscle cell development; GO:0032269 negative regulation of cellular protein metabolic process; GO:0046716 muscle cell cellular homeostasis; GO:0048583 regulation of response to stimulus; GO:2001257 regulation of cation channel activity; GO:0003015 heart process; GO:0032412 regulation of ion transmembrane transporter activity; GO:0003013 circulatory system process; GO:0051094 positive regulation of developmental process; GO:0010975 regulation of neuron projection development; GO:0050794 regulation of cellular process; GO:0055001 muscle cell development; GO:0044707 single-multicellular organism process; GO:0002028 regulation of sodium ion transport; GO:0030049 muscle filament sliding; GO:0034764 positive regulation of transmembrane transport; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0032844 regulation of homeostatic process; GO:0060249 anatomical structure homeostasis; GO:0051239 regulation of multicellular organismal process; GO:0045597 positive regulation of cell differentiation; GO:0060341 regulation of cellular localization; GO:0035994 response to muscle stretch; GO:0019722 calcium-mediated signaling; GO:0010959 regulation of metal ion transport; GO:0061061 muscle structure development; GO:0001933 negative regulation of protein phosphorylation; GO:0050848 regulation of calcium-mediated signaling; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0034613 cellular protein localization; GO:0009966 regulation of signal transduction; GO:0006461 protein complex assembly; GO:1904062 regulation of cation transmembrane transport; GO:0032409 regulation of transporter activity; GO:0051282 regulation of sequestering of calcium ion; GO:1902531 regulation of intracellular signal transduction; GO:0044458 motile cilium assembly; GO:0033135 regulation of peptidyl-serine phosphorylation; GO:0048731 system development; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0051924 regulation of calcium ion transport; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0030031 cell projection assembly; GO:0043270 positive regulation of ion transport; GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling; GO:2000169 regulation of peptidyl-cysteine S-nitrosylation; GO:1904064 positive regulation of cation transmembrane transport; GO:0010976 positive regulation of neuron projection development; GO:0006996 organelle organization; GO:0002027 regulation of heart rate; GO:0030029 actin filament-based process; GO:0006928 movement of cell or subcellular component; GO:0050769 positive regulation of neurogenesis; GO:1902305 regulation of sodium ion transmembrane transport; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0045936 negative regulation of phosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling; GO:0030048 actin filament-based movement; GO:0045666 positive regulation of neuron differentiation; GO:0003012 muscle system process; GO:0070252 actin-mediated cell contraction; GO:0048747 muscle fiber development; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity; GO:0031400 negative regulation of protein modification process; GO:0051130 positive regulation of cellular component organization; GO:0033137 negative regulation of peptidyl-serine phosphorylation; GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0055117 regulation of cardiac muscle contraction; GO:0022607 cellular component assembly; GO:0010765 positive regulation of sodium ion transport; GO:0014819 regulation of skeletal muscle contraction; GO:0001508 action potential; GO:0033036 macromolecule localization; GO:0010720 positive regulation of cell development; GO:1901385 regulation of voltage-gated calcium channel activity; GO:0032502 developmental process; GO:0071822 protein complex subunit organization; GO:0051279 regulation of release of sequestered calcium ion into cytosol; GO:0043043 peptide biosynthetic process; GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; GO:0051962 positive regulation of nervous system development; GO:0019725 cellular homeostasis; GO:0048522 positive regulation of cellular process; GO:0022898 regulation of transmembrane transporter activity; GO:0043603 cellular amide metabolic process; GO:0090257 regulation of muscle system process; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0006942 regulation of striated muscle contraction; GO:0051050 positive regulation of transport; GO:0042391 regulation of membrane potential; GO:1902589 single-organism organelle organization; GO:0086001 cardiac muscle cell action potential; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0034767 positive regulation of ion transmembrane transport; GO:0030030 cell projection organization; GO:0045664 regulation of neuron differentiation; GO:0007517 muscle organ development; GO:2000651 positive regulation of sodium ion transmembrane transporter activity; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation; GO:0019220 regulation of phosphate metabolic process; GO:0070271 protein complex biogenesis; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0016043 cellular component organization; GO:2000021 regulation of ion homeostasis; GO:0032411 positive regulation of transporter activity; GO:0060255 regulation of macromolecule metabolic process; GO:1903522 regulation of blood circulation; GO:0031344 regulation of cell projection organization; GO:0008016 regulation of heart contraction; GO:0060048 cardiac muscle contraction; GO:0031324 negative regulation of cellular metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0009612 response to mechanical stimulus; GO:0030154 cell differentiation; GO:0006936 muscle contraction; GO:0070925 organelle assembly; GO:0042326 negative regulation of phosphorylation; GO:1903169 regulation of calcium ion transmembrane transport; GO:0008015 blood circulation; GO:0034641 cellular nitrogen compound metabolic process; GO:0060047 heart contraction; GO:0009987 cellular process; GO:0043623 cellular protein complex assembly; GO:0045595 regulation of cell differentiation; GO:0034622 cellular macromolecular complex assembly; GO:0051146 striated muscle cell differentiation; GO:0003008 system process; GO:0035556 intracellular signal transduction; GO:0033275 actin-myosin filament sliding; GO:0051049 regulation of transport; GO:0090279 regulation of calcium ion import; GO:0006937 regulation of muscle contraction; GO:0001932 regulation of protein phosphorylation; GO:0006807 nitrogen compound metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0051641 cellular localization; GO:0070727 cellular macromolecule localization; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034765 regulation of ion transmembrane transport; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0010563 negative regulation of phosphorus metabolic process; GO:0010522 regulation of calcium ion transport into cytosol; GO:0042692 muscle cell differentiation; GO:0051248 negative regulation of protein metabolic process; GO:0051128 regulation of cellular component organization; GO:0043604 amide biosynthetic process; GO:1902307 positive regulation of sodium ion transmembrane transport; GO:0071840 cellular component organization or biogenesis; GO:0050767 regulation of neurogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0098857 membrane microdomain; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0030054 cell junction; GO:0030016 myofibril; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0030018 Z disc; GO:0098858 actin-based cell projection; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0031674 I band; GO:0044422 organelle part; GO:0016013 syntrophin complex; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0098590 plasma membrane region; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0098589 membrane region; GO:0043292 contractile fiber; GO:0097060 synaptic membrane; GO:0043005 neuron projection; GO:0030175 filopodium; GO:0030055 cell-substrate junction; GO:0045121 membrane raft; GO:0043227 membrane-bounded organelle; GO:0044306 neuron projection terminus; GO:0097458 neuron part; GO:0044456 synapse part; GO:0043229 intracellular organelle; GO:0090665 glycoprotein complex; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0098797 plasma membrane protein complex; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0031527 filopodium membrane; GO:0045202 synapse; GO:0005886 plasma membrane; GO:0099081 supramolecular polymer; GO:0016010 dystrophin-associated glycoprotein complex; GO:0045211 postsynaptic membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0098794 postsynapse; GO:0044459 plasma membrane part; GO:0043034 costamere; GO:0030017 sarcomere; GO:0031253 cell projection membrane; GO:0044449 contractile fiber part; GO:0009986 cell surface; GO:0043234 protein complex; GO:0042383 sarcolemma; GO:0044444 cytoplasmic part; ","GO:0002162 dystroglycan binding; GO:0043167 ion binding; GO:0050998 nitric-oxide synthase binding; GO:0005515 protein binding; GO:0008270 zinc ion binding; GO:0008307 structural constituent of muscle; GO:0097367 carbohydrate derivative binding; GO:0008092 cytoskeletal protein binding; GO:0046914 transition metal ion binding; GO:0005200 structural constituent of cytoskeleton; GO:0017166 vinculin binding; GO:0005488 binding; GO:0003779 actin binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0017022 myosin binding; GO:0001948 glycoprotein binding; GO:0005198 structural molecule activity; GO:0019899 enzyme binding; ","K10366","DMD; dystrophin","hsa05414 Dilated cardiomyopathy (DCM) - Homo sapiens (human); hsa05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human); hsa05416 Viral myocarditis - Homo sapiens (human); hsa05410 Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human); ","IPR015154; IPR001202; IPR001715; IPR011992; IPR015153; IPR000433; ","\"EF-hand domain, type 2; WW domain; Calponin homology domain; EF-hand domain pair; EF-hand domain, type 1; Zinc finger, ZZ-type; \"\r"]
["P11586","C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1","MTHFD1",101.56,77.988,21.9,20,28,20,0.972,0.974,0.978,0.989,1.045,1.016,1.043,0.12,"cytoplasm\r","GO:0042559 pteridine-containing compound biosynthetic process; GO:0065008 regulation of biological quality; GO:0000097 sulfur amino acid biosynthetic process; GO:0035148 tube formation; GO:0043009 chordate embryonic development; GO:0002262 myeloid cell homeostasis; GO:0052803 imidazole-containing compound metabolic process; GO:0042398 cellular modified amino acid biosynthetic process; GO:0009257 10-formyltetrahydrofolate biosynthetic process; GO:0044237 cellular metabolic process; GO:0044272 sulfur compound biosynthetic process; GO:0008152 metabolic process; GO:0007507 heart development; GO:0048562 embryonic organ morphogenesis; GO:1901607 alpha-amino acid biosynthetic process; GO:0046112 nucleobase biosynthetic process; GO:0006555 methionine metabolic process; GO:0009108 coenzyme biosynthetic process; GO:0048706 embryonic skeletal system development; GO:0009790 embryo development; GO:0048598 embryonic morphogenesis; GO:0007399 nervous system development; GO:0006790 sulfur compound metabolic process; GO:0018130 heterocycle biosynthetic process; GO:0046653 tetrahydrofolate metabolic process; GO:0035239 tube morphogenesis; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0072521 purine-containing compound metabolic process; GO:0006732 coenzyme metabolic process; GO:0032501 multicellular organismal process; GO:0090407 organophosphate biosynthetic process; GO:0009092 homoserine metabolic process; GO:0048872 homeostasis of number of cells; GO:0048513 animal organ development; GO:0044710 single-organism metabolic process; GO:0009112 nucleobase metabolic process; GO:0009887 animal organ morphogenesis; GO:0006164 purine nucleotide biosynthetic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0043436 oxoacid metabolic process; GO:0072359 circulatory system development; GO:0002009 morphogenesis of an epithelium; GO:0044707 single-multicellular organism process; GO:0009066 aspartate family amino acid metabolic process; GO:0000105 histidine biosynthetic process; GO:0009086 methionine biosynthetic process; GO:0046655 folic acid metabolic process; GO:0009653 anatomical structure morphogenesis; GO:0060606 tube closure; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006547 histidine metabolic process; GO:1904888 cranial skeletal system development; GO:0016331 morphogenesis of embryonic epithelium; GO:0007275 multicellular organism development; GO:0001843 neural tube closure; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0009070 serine family amino acid biosynthetic process; GO:0006767 water-soluble vitamin metabolic process; GO:0009067 aspartate family amino acid biosynthetic process; GO:0008652 cellular amino acid biosynthetic process; GO:0060562 epithelial tube morphogenesis; GO:0044711 single-organism biosynthetic process; GO:0048731 system development; GO:0009396 folic acid-containing compound biosynthetic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0002376 immune system process; GO:0006144 purine nucleobase metabolic process; GO:1901605 alpha-amino acid metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0006163 purine nucleotide metabolic process; GO:0048705 skeletal system morphogenesis; GO:0006793 phosphorus metabolic process; GO:0044283 small molecule biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0048701 embryonic cranial skeleton morphogenesis; GO:0009256 10-formyltetrahydrofolate metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0051188 cofactor biosynthetic process; GO:0001841 neural tube formation; GO:0046148 pigment biosynthetic process; GO:0061053 somite development; GO:0016053 organic acid biosynthetic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0035999 tetrahydrofolate interconversion; GO:0006796 phosphate-containing compound metabolic process; GO:0000096 sulfur amino acid metabolic process; GO:0048729 tissue morphogenesis; GO:0006520 cellular amino acid metabolic process; GO:0048703 embryonic viscerocranium morphogenesis; GO:0006753 nucleoside phosphate metabolic process; GO:0006534 cysteine metabolic process; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0035295 tube development; GO:0009888 tissue development; GO:0009113 purine nucleobase biosynthetic process; GO:0055114 oxidation-reduction process; GO:1901360 organic cyclic compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0001776 leukocyte homeostasis; GO:0051186 cofactor metabolic process; GO:0043650 dicarboxylic acid biosynthetic process; GO:0046394 carboxylic acid biosynthetic process; GO:0009069 serine family amino acid metabolic process; GO:0072522 purine-containing compound biosynthetic process; GO:0050667 homocysteine metabolic process; GO:0006082 organic acid metabolic process; GO:0006760 folic acid-containing compound metabolic process; GO:0048856 anatomical structure development; GO:0001501 skeletal system development; GO:0043648 dicarboxylic acid metabolic process; GO:0009165 nucleotide biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0001780 neutrophil homeostasis; GO:0048568 embryonic organ development; GO:1901566 organonitrogen compound biosynthetic process; GO:0021915 neural tube development; GO:0071704 organic substance metabolic process; GO:0072175 epithelial tube formation; GO:0042592 homeostatic process; GO:0006766 vitamin metabolic process; GO:0006575 cellular modified amino acid metabolic process; GO:0006730 one-carbon metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0046654 tetrahydrofolate biosynthetic process; GO:0048704 embryonic skeletal system morphogenesis; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0019346 transsulfuration; GO:0042440 pigment metabolic process; GO:0009792 embryo development ending in birth or egg hatching; GO:0006807 nitrogen compound metabolic process; GO:0042558 pteridine-containing compound metabolic process; GO:0044249 cellular biosynthetic process; GO:0001838 embryonic epithelial tube formation; GO:0014020 primary neural tube formation; GO:0048702 embryonic neurocranium morphogenesis; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0044767 single-organism developmental process; GO:0019752 carboxylic acid metabolic process; GO:0043604 amide biosynthetic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors; GO:1901265 nucleoside phosphate binding; GO:0016874 ligase activity; GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity; GO:0000166 nucleotide binding; GO:0019238 cyclohydrolase activity; GO:0016491 oxidoreductase activity; GO:0016879 ligase activity, forming carbon-nitrogen bonds; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines; GO:0004477 methenyltetrahydrofolate cyclohydrolase activity; GO:0004486 methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0004329 formate-tetrahydrofolate ligase activity; GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; GO:0036094 small molecule binding; ","K00288","MTHFD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]","hsa00670 One carbon pool by folate - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR020631; IPR027417; IPR016040; IPR020630; ","\"Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain; P-loop containing nucleoside triphosphate hydrolase; NAD(P)-binding domain; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; \"\r"]
["P11597","Cholesteryl ester transfer protein OS=Homo sapiens OX=9606 GN=CETP","CETP",54.756,14.362,5.3,2,2,2,0.813,0.864,0.939,1.119,1.136,1.119,1.29,0.0259,"extracellular\r","GO:0034367 macromolecular complex remodeling; GO:0051093 negative regulation of developmental process; GO:0046470 phosphatidylcholine metabolic process; GO:0065008 regulation of biological quality; GO:0015850 organic hydroxy compound transport; GO:0046486 glycerolipid metabolic process; GO:0032371 regulation of sterol transport; GO:0006066 alcohol metabolic process; GO:0030301 cholesterol transport; GO:0044699 single-organism process; GO:0070328 triglyceride homeostasis; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0042157 lipoprotein metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0055091 phospholipid homeostasis; GO:0008152 metabolic process; GO:0034197 triglyceride transport; GO:0032879 regulation of localization; GO:0006639 acylglycerol metabolic process; GO:0071825 protein-lipid complex subunit organization; GO:0006650 glycerophospholipid metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0045596 negative regulation of cell differentiation; GO:0033036 macromolecule localization; GO:0043691 reverse cholesterol transport; GO:0055088 lipid homeostasis; GO:0044765 single-organism transport; GO:0006629 lipid metabolic process; GO:0071827 plasma lipoprotein particle organization; GO:0006869 lipid transport; GO:0050801 ion homeostasis; GO:0010743 regulation of macrophage derived foam cell differentiation; GO:0044281 small molecule metabolic process; GO:0008202 steroid metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0055081 anion homeostasis; GO:0032501 multicellular organismal process; GO:0032374 regulation of cholesterol transport; GO:0006810 transport; GO:0015748 organophosphate ester transport; GO:0050789 regulation of biological process; GO:0044710 single-organism metabolic process; GO:0010745 negative regulation of macrophage derived foam cell differentiation; GO:0050794 regulation of cellular process; GO:0015918 sterol transport; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:1901615 organic hydroxy compound metabolic process; GO:0034374 low-density lipoprotein particle remodeling; GO:1902652 secondary alcohol metabolic process; GO:0032368 regulation of lipid transport; GO:0034372 very-low-density lipoprotein particle remodeling; GO:0097164 ammonium ion metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0016125 sterol metabolic process; GO:0071704 organic substance metabolic process; GO:0097006 regulation of plasma lipoprotein particle levels; GO:0034370 triglyceride-rich lipoprotein particle remodeling; GO:0042592 homeostatic process; GO:1902578 single-organism localization; GO:0034369 plasma lipoprotein particle remodeling; GO:0006898 receptor-mediated endocytosis; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0045595 regulation of cell differentiation; GO:0006638 neutral lipid metabolic process; GO:0034196 acylglycerol transport; GO:0008203 cholesterol metabolic process; GO:0051049 regulation of transport; GO:0016192 vesicle-mediated transport; GO:0006807 nitrogen compound metabolic process; GO:0010876 lipid localization; GO:0071702 organic substance transport; GO:0015914 phospholipid transport; GO:0042632 cholesterol homeostasis; GO:0006897 endocytosis; GO:0044238 primary metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0010874 regulation of cholesterol efflux; GO:0006820 anion transport; GO:0015711 organic anion transport; GO:0006641 triglyceride metabolic process; GO:0006793 phosphorus metabolic process; GO:0055090 acylglycerol homeostasis; GO:0006811 ion transport; GO:0055092 sterol homeostasis; GO:0019637 organophosphate metabolic process; GO:0034375 high-density lipoprotein particle remodeling; GO:0006644 phospholipid metabolic process; GO:0034368 protein-lipid complex remodeling; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:1901564 organonitrogen compound metabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0032994 protein-lipid complex; GO:1990777 lipoprotein particle; GO:0034358 plasma lipoprotein particle; GO:1903561 extracellular vesicle; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0034364 high-density lipoprotein particle; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:0015485 cholesterol binding; GO:0032934 sterol binding; GO:0070405 ammonium ion binding; GO:0017129 triglyceride binding; GO:0043167 ion binding; GO:0005319 lipid transporter activity; GO:0022892 substrate-specific transporter activity; GO:0005496 steroid binding; GO:0097159 organic cyclic compound binding; GO:0031210 phosphatidylcholine binding; GO:0050997 quaternary ammonium group binding; GO:0017127 cholesterol transporter activity; GO:0043178 alcohol binding; GO:0005488 binding; GO:0005543 phospholipid binding; GO:0015248 sterol transporter activity; GO:0008289 lipid binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0036094 small molecule binding; GO:0005215 transporter activity; GO:0005548 phospholipid transporter activity; ","K16835","CETP; cholesteryl ester transfer protein","hsa04979 Cholesterol metabolism - Homo sapiens (human); ","IPR017943; IPR017942; IPR001124; ","\"Bactericidal permeability-increasing protein, alpha/beta domain; Lipid-binding serum glycoprotein, N-terminal; Lipid-binding serum glycoprotein, C-terminal; \"\r"]
["P11678","Eosinophil peroxidase OS=Homo sapiens OX=9606 GN=EPX","EPX",81.04,2.0506,2.4,2,2,1,1.168,1.305,1.074,0.861,0.853,0.777,0.702,0.00576,"extracellular\r","GO:0045321 leukocyte activation; GO:0051674 localization of cell; GO:0098542 defense response to other organism; GO:0044699 single-organism process; GO:0051241 negative regulation of multicellular organismal process; GO:0001818 negative regulation of cytokine production; GO:0044237 cellular metabolic process; GO:0032753 positive regulation of interleukin-4 production; GO:0009607 response to biotic stimulus; GO:0051234 establishment of localization; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0032674 regulation of interleukin-5 production; GO:0032673 regulation of interleukin-4 production; GO:0097529 myeloid leukocyte migration; GO:0051240 positive regulation of multicellular organismal process; GO:0006979 response to oxidative stress; GO:0098869 cellular oxidant detoxification; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0002443 leukocyte mediated immunity; GO:0032693 negative regulation of interleukin-10 production; GO:0055114 oxidation-reduction process; GO:0009636 response to toxic substance; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0048870 cell motility; GO:0051704 multi-organism process; GO:0002444 myeloid leukocyte mediated immunity; GO:0006810 transport; GO:0042221 response to chemical; GO:0050900 leukocyte migration; GO:0050789 regulation of biological process; GO:0032940 secretion by cell; GO:0044710 single-organism metabolic process; GO:0040011 locomotion; GO:0006952 defense response; GO:0043299 leukocyte degranulation; GO:0098754 detoxification; GO:0016477 cell migration; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0001819 positive regulation of cytokine production; GO:0048519 negative regulation of biological process; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0051239 regulation of multicellular organismal process; GO:0097530 granulocyte migration; GO:0042743 hydrogen peroxide metabolic process; GO:1990748 cellular detoxification; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0072593 reactive oxygen species metabolic process; GO:0032714 negative regulation of interleukin-5 production; GO:0044248 cellular catabolic process; GO:0036230 granulocyte activation; GO:0042744 hydrogen peroxide catabolic process; GO:0009987 cellular process; GO:0006950 response to stress; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0043312 neutrophil degranulation; GO:0002263 cell activation involved in immune response; GO:0048518 positive regulation of biological process; GO:0002366 leukocyte activation involved in immune response; GO:0032653 regulation of interleukin-10 production; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0002215 defense response to nematode; GO:0072677 eosinophil migration; GO:0006928 movement of cell or subcellular component; GO:0001817 regulation of cytokine production; GO:0001775 cell activation; GO:0006955 immune response; GO:0051179 localization; GO:0009056 catabolic process; GO:0065007 biological regulation; GO:0006887 exocytosis; ","GO:0034774 secretory granule lumen; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044433 cytoplasmic vesicle part; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0060205 cytoplasmic vesicle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0020037 heme binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0016209 antioxidant activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0004601 peroxidase activity; GO:0046906 tetrapyrrole binding; GO:0016684 oxidoreductase activity, acting on peroxide as acceptor; GO:0016491 oxidoreductase activity; ","K10788","EPX; eosinophil peroxidase [EC:1.11.1.7]","hsa05310 Asthma - Homo sapiens (human); "]
["P11717","Cation-independent mannose-6-phosphate receptor OS=Homo sapiens OX=9606 GN=IGF2R","IGF2R",274.37,17.652,3.3,9,11,9,1.024,1.045,0.99,1.003,0.978,1.006,0.976,0.262,"plasma membrane\r","GO:0044700 single organism signaling; GO:0031100 animal organ regeneration; GO:0001101 response to acid chemical; GO:0010941 regulation of cell death; GO:0048732 gland development; GO:0045321 leukocyte activation; GO:0022414 reproductive process; GO:0007166 cell surface receptor signaling pathway; GO:0044699 single-organism process; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0044702 single organism reproductive process; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0048009 insulin-like growth factor receptor signaling pathway; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0019953 sexual reproduction; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0002444 myeloid leukocyte mediated immunity; GO:0051704 multi-organism process; GO:0010942 positive regulation of cell death; GO:0006810 transport; GO:0048513 animal organ development; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032526 response to retinoic acid; GO:0032940 secretion by cell; GO:0043299 leukocyte degranulation; GO:0048609 multicellular organismal reproductive process; GO:0048856 anatomical structure development; GO:0043068 positive regulation of programmed cell death; GO:0050794 regulation of cellular process; GO:0000003 reproduction; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:1901700 response to oxygen-containing compound; GO:0043067 regulation of programmed cell death; GO:0043065 positive regulation of apoptotic process; GO:0009791 post-embryonic development; GO:0050896 response to stimulus; GO:0033993 response to lipid; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0061008 hepaticobiliary system development; GO:0007275 multicellular organism development; GO:0006898 receptor-mediated endocytosis; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0048232 male gamete generation; GO:0048731 system development; GO:0007283 spermatogenesis; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0043312 neutrophil degranulation; GO:0006897 endocytosis; GO:0002263 cell activation involved in immune response; GO:0048518 positive regulation of biological process; GO:0007276 gamete generation; GO:0007186 G-protein coupled receptor signaling pathway; GO:0002366 leukocyte activation involved in immune response; GO:0032504 multicellular organism reproduction; GO:0001889 liver development; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:0044767 single-organism developmental process; GO:0061024 membrane organization; GO:0044703 multi-organism reproductive process; GO:0001775 cell activation; GO:0006955 immune response; GO:0031099 regeneration; GO:0051179 localization; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0006887 exocytosis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0032588 trans-Golgi network membrane; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0005765 lysosomal membrane; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0030136 clathrin-coated vesicle; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:0098791 Golgi subcompartment; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0031226 intrinsic component of plasma membrane; GO:0005770 late endosome; GO:0048475 coated membrane; GO:0031967 organelle envelope; GO:0070161 anchoring junction; GO:0012506 vesicle membrane; GO:0005798 Golgi-associated vesicle; GO:0030135 coated vesicle; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0030667 secretory granule membrane; GO:0044437 vacuolar part; GO:0031975 envelope; GO:0030118 clathrin coat; GO:0005773 vacuole; GO:0030117 membrane coat; GO:0043234 protein complex; GO:0030133 transport vesicle; GO:0043230 extracellular organelle; GO:0005615 extracellular space; GO:0031410 cytoplasmic vesicle; GO:0098796 membrane protein complex; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0030662 coated vesicle membrane; GO:0005641 nuclear envelope lumen; GO:0031974 membrane-enclosed lumen; GO:0030140 trans-Golgi network transport vesicle; GO:0031970 organelle envelope lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0044431 Golgi apparatus part; GO:0005768 endosome; GO:0030141 secretory granule; GO:0030139 endocytic vesicle; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0005635 nuclear envelope; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0030665 clathrin-coated vesicle membrane; GO:0016021 integral component of membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0005802 trans-Golgi network; GO:0005774 vacuolar membrane; GO:0009986 cell surface; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; GO:0031984 organelle subcompartment; GO:0044428 nuclear part; ","GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0031995 insulin-like growth factor II binding; GO:0019838 growth factor binding; GO:0004713 protein tyrosine kinase activity; GO:0005515 protein binding; GO:0048029 monosaccharide binding; GO:0004672 protein kinase activity; GO:0004888 transmembrane signaling receptor activity; GO:0004871 signal transducer activity; GO:0004714 transmembrane receptor protein tyrosine kinase activity; GO:0005010 insulin-like growth factor-activated receptor activity; GO:0031406 carboxylic acid binding; GO:0042802 identical protein binding; GO:0016301 kinase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0008289 lipid binding; GO:0043168 anion binding; GO:0016740 transferase activity; GO:0001972 retinoic acid binding; GO:0005215 transporter activity; GO:0005520 insulin-like growth factor binding; GO:0038023 signaling receptor activity; GO:0004930 G-protein coupled receptor activity; GO:0043167 ion binding; GO:0005501 retinoid binding; GO:0043177 organic acid binding; GO:0019840 isoprenoid binding; GO:0033293 monocarboxylic acid binding; GO:0051219 phosphoprotein binding; GO:0019199 transmembrane receptor protein kinase activity; GO:0097367 carbohydrate derivative binding; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0005537 mannose binding; GO:0030246 carbohydrate binding; GO:0001965 G-protein alpha-subunit binding; GO:0001948 glycoprotein binding; GO:0019899 enzyme binding; GO:0099600 transmembrane receptor activity; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0036094 small molecule binding; ","K06564","IGF2R; insulin-like growth factor 2 receptor","hsa04142 Lysosome - Homo sapiens (human); hsa04144 Endocytosis - Homo sapiens (human); ","IPR009011; IPR013806; IPR000562; ","\"Mannose-6-phosphate receptor binding domain; Kringle-like fold; Fibronectin, type II, collagen-binding; \"\r"]
["P11766","Alcohol dehydrogenase class-3 OS=Homo sapiens OX=9606 GN=ADH5","ADH5",39.724,132.21,33.2,12,29,12,1.072,1.049,1.056,0.981,0.939,0.927,0.896,0.00386,"cytoplasm\r","GO:0045777 positive regulation of blood pressure; GO:0065008 regulation of biological quality; GO:0006066 alcohol metabolic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0009607 response to biotic stimulus; GO:0009605 response to external stimulus; GO:0051409 response to nitrosative stress; GO:0008152 metabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0034308 primary alcohol metabolic process; GO:0046292 formaldehyde metabolic process; GO:0006629 lipid metabolic process; GO:0055114 oxidation-reduction process; GO:0002237 response to molecule of bacterial origin; GO:0003016 respiratory system process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006081 cellular aldehyde metabolic process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:1901575 organic substance catabolic process; GO:0042221 response to chemical; GO:0018198 peptidyl-cysteine modification; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0016101 diterpenoid metabolic process; GO:0006464 cellular protein modification process; GO:0036211 protein modification process; GO:0003013 circulatory system process; GO:0008217 regulation of blood pressure; GO:0044707 single-multicellular organism process; GO:0006069 ethanol oxidation; GO:1901615 organic hydroxy compound metabolic process; GO:1901700 response to oxygen-containing compound; GO:0044267 cellular protein metabolic process; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0071704 organic substance metabolic process; GO:0033993 response to lipid; GO:0018119 peptidyl-cysteine S-nitrosylation; GO:0006067 ethanol metabolic process; GO:0008015 blood circulation; GO:0051775 response to redox state; GO:0044248 cellular catabolic process; GO:0001523 retinoid metabolic process; GO:0046294 formaldehyde catabolic process; GO:0009987 cellular process; GO:0017014 protein nitrosylation; GO:0009617 response to bacterium; GO:0006720 isoprenoid metabolic process; GO:0003008 system process; GO:0006950 response to stress; GO:0032496 response to lipopolysaccharide; GO:0044712 single-organism catabolic process; GO:0044282 small molecule catabolic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0018193 peptidyl-amino acid modification; GO:0007585 respiratory gaseous exchange; GO:0046185 aldehyde catabolic process; GO:0006721 terpenoid metabolic process; GO:0043412 macromolecule modification; GO:0009056 catabolic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0046983 protein dimerization activity; GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors; GO:0043167 ion binding; GO:0043177 organic acid binding; GO:0005515 protein binding; GO:0033293 monocarboxylic acid binding; GO:0008270 zinc ion binding; GO:0004029 aldehyde dehydrogenase (NAD) activity; GO:0051903 S-(hydroxymethyl)glutathione dehydrogenase activity; GO:0016491 oxidoreductase activity; GO:0016614 oxidoreductase activity, acting on CH-OH group of donors; GO:0009055 electron carrier activity; GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; GO:0031406 carboxylic acid binding; GO:0042802 identical protein binding; GO:0046914 transition metal ion binding; GO:0018467 formaldehyde dehydrogenase activity; GO:0003824 catalytic activity; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0008289 lipid binding; GO:0004022 alcohol dehydrogenase (NAD) activity; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0043168 anion binding; GO:0005504 fatty acid binding; GO:0036094 small molecule binding; ","K00121","frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]","hsa05204 Chemical carcinogenesis - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00980 Metabolism of xenobiotics by cytochrome P450 - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); hsa00071 Fatty acid degradation - Homo sapiens (human); hsa00982 Drug metabolism - cytochrome P450 - Homo sapiens (human); hsa00350 Tyrosine metabolism - Homo sapiens (human); hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human); hsa00830 Retinol metabolism - Homo sapiens (human); ","IPR011032; IPR016040; IPR013154; IPR013149; ","\"GroES-like; NAD(P)-binding domain; Alcohol dehydrogenase, N-terminal; Alcohol dehydrogenase, C-terminal; \"\r"]
["P11802","Cyclin-dependent kinase 4 OS=Homo sapiens OX=9606 GN=CDK4","CDK4",33.729,4.9405,6.9,2,3,1,1.096,1.28,1.072,0.79,0.8,0.988,0.748,0.0328,"cytoplasm\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0010941 regulation of cell death; GO:0032270 positive regulation of cellular protein metabolic process; GO:0010608 posttranscriptional regulation of gene expression; GO:0009891 positive regulation of biosynthetic process; GO:0019216 regulation of lipid metabolic process; GO:0071345 cellular response to cytokine stimulus; GO:0010564 regulation of cell cycle process; GO:0071157 negative regulation of cell cycle arrest; GO:0044237 cellular metabolic process; GO:0002088 lens development in camera-type eye; GO:0009607 response to biotic stimulus; GO:0048145 regulation of fibroblast proliferation; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0048146 positive regulation of fibroblast proliferation; GO:0032535 regulation of cellular component size; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0009719 response to endogenous stimulus; GO:0044770 cell cycle phase transition; GO:0061448 connective tissue development; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0090068 positive regulation of cell cycle process; GO:1901652 response to peptide; GO:0014070 response to organic cyclic compound; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0040014 regulation of multicellular organism growth; GO:0080090 regulation of primary metabolic process; GO:0009894 regulation of catabolic process; GO:0071398 cellular response to fatty acid; GO:0044763 single-organism cellular process; GO:1902751 positive regulation of cell cycle G2/M phase transition; GO:0031323 regulation of cellular metabolic process; GO:0071353 cellular response to interleukin-4; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0071396 cellular response to lipid; GO:0010243 response to organonitrogen compound; GO:0048513 animal organ development; GO:0010948 negative regulation of cell cycle process; GO:0045931 positive regulation of mitotic cell cycle; GO:0050790 regulation of catalytic activity; GO:0046890 regulation of lipid biosynthetic process; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0032869 cellular response to insulin stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0051301 cell division; GO:0050994 regulation of lipid catabolic process; GO:0043068 positive regulation of programmed cell death; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0016310 phosphorylation; GO:0007346 regulation of mitotic cell cycle; GO:0042127 regulation of cell proliferation; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:1901700 response to oxygen-containing compound; GO:0043067 regulation of programmed cell death; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0071362 cellular response to ether; GO:1903047 mitotic cell cycle process; GO:1901989 positive regulation of cell cycle phase transition; GO:0051239 regulation of multicellular organismal process; GO:0045472 response to ether; GO:0042493 response to drug; GO:0001654 eye development; GO:0071229 cellular response to acid chemical; GO:1901987 regulation of cell cycle phase transition; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0070482 response to oxygen levels; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0010389 regulation of G2/M transition of mitotic cell cycle; GO:0007275 multicellular organism development; GO:0055093 response to hyperoxia; GO:0070542 response to fatty acid; GO:0009966 regulation of signal transduction; GO:0070670 response to interleukin-4; GO:0009617 response to bacterium; GO:0044772 mitotic cell cycle phase transition; GO:0045787 positive regulation of cell cycle; GO:0006950 response to stress; GO:0032496 response to lipopolysaccharide; GO:0048731 system development; GO:0071407 cellular response to organic cyclic compound; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1904636 response to ionomycin; GO:0034248 regulation of cellular amide metabolic process; GO:1904627 response to phorbol 13-acetate 12-myristate; GO:0051247 positive regulation of protein metabolic process; GO:0006793 phosphorus metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0071219 cellular response to molecule of bacterial origin; GO:0031328 positive regulation of cellular biosynthetic process; GO:0043412 macromolecule modification; GO:0007423 sensory organ development; GO:0050793 regulation of developmental process; GO:0008284 positive regulation of cell proliferation; GO:0031100 animal organ regeneration; GO:0001101 response to acid chemical; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0006796 phosphate-containing compound metabolic process; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:1901653 cellular response to peptide; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0045793 positive regulation of cell size; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0010035 response to inorganic substance; GO:0051726 regulation of cell cycle; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0009888 tissue development; GO:0034097 response to cytokine; GO:0031326 regulation of cellular biosynthetic process; GO:0045727 positive regulation of translation; GO:0002237 response to molecule of bacterial origin; GO:0009636 response to toxic substance; GO:0048522 positive regulation of cellular process; GO:0033574 response to testosterone; GO:0023052 signaling; GO:0010038 response to metal ion; GO:0010942 positive regulation of cell death; GO:0071417 cellular response to organonitrogen compound; GO:0007623 circadian rhythm; GO:0036296 response to increased oxygen levels; GO:0032868 response to insulin; GO:1904628 cellular response to phorbol 13-acetate 12-myristate; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0042221 response to chemical; GO:0043434 response to peptide hormone; GO:1901699 cellular response to nitrogen compound; GO:0032870 cellular response to hormone stimulus; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0010288 response to lead ion; GO:0019220 regulation of phosphate metabolic process; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0043549 regulation of kinase activity; GO:0045859 regulation of protein kinase activity; GO:0016043 cellular component organization; GO:0045786 negative regulation of cell cycle; GO:0043010 camera-type eye development; GO:0040008 regulation of growth; GO:0071222 cellular response to lipopolysaccharide; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0043065 positive regulation of apoptotic process; GO:1900076 regulation of cellular response to insulin stimulus; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0048638 regulation of developmental growth; GO:0051707 response to other organism; GO:0071704 organic substance metabolic process; GO:0033993 response to lipid; GO:0008361 regulation of cell size; GO:0071216 cellular response to biotic stimulus; GO:0006468 protein phosphorylation; GO:0071375 cellular response to peptide hormone stimulus; GO:0000082 G1/S transition of mitotic cell cycle; GO:0009987 cellular process; GO:0071156 regulation of cell cycle arrest; GO:0044843 cell cycle G1/S phase transition; GO:0001932 regulation of protein phosphorylation; GO:0010556 regulation of macromolecule biosynthetic process; GO:1902749 regulation of cell cycle G2/M phase transition; GO:0048518 positive regulation of biological process; GO:0046626 regulation of insulin receptor signaling pathway; GO:1901701 cellular response to oxygen-containing compound; GO:0071495 cellular response to endogenous stimulus; GO:0060612 adipose tissue development; GO:0048511 rhythmic process; GO:0006417 regulation of translation; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:1904637 cellular response to ionomycin; GO:0034250 positive regulation of cellular amide metabolic process; GO:0090066 regulation of anatomical structure size; GO:0022402 cell cycle process; GO:0010971 positive regulation of G2/M transition of mitotic cell cycle; GO:0009725 response to hormone; GO:0031099 regeneration; GO:1901992 positive regulation of mitotic cell cycle phase transition; GO:0042981 regulation of apoptotic process; GO:0007049 cell cycle; GO:1901654 response to ketone; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0061695 transferase complex, transferring phosphorus-containing groups; GO:0031090 organelle membrane; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:1902554 serine/threonine protein kinase complex; GO:0005911 cell-cell junction; GO:0005623 cell; GO:1902911 protein kinase complex; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070160 occluding junction; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0031965 nuclear membrane; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0048471 perinuclear region of cytoplasm; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005635 nuclear envelope; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0000307 cyclin-dependent protein kinase holoenzyme complex; GO:0005730 nucleolus; GO:1990234 transferase complex; GO:0005829 cytosol; GO:0005667 transcription factor complex; GO:0005923 bicellular tight junction; GO:0043296 apical junction complex; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0000785 chromatin; GO:0031975 envelope; GO:0097129 cyclin D2-CDK4 complex; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity; GO:0004693 cyclin-dependent protein serine/threonine kinase activity; GO:0005515 protein binding; GO:0004672 protein kinase activity; GO:0019207 kinase regulator activity; GO:0098772 molecular function regulator; GO:0030332 cyclin binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016301 kinase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0019887 protein kinase regulator activity; GO:0000166 nucleotide binding; GO:0097472 cyclin-dependent protein kinase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0030234 enzyme regulator activity; GO:0004674 protein serine/threonine kinase activity; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0032403 protein complex binding; GO:0036094 small molecule binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K02089","CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]","hsa04218 Cellular senescence - Homo sapiens (human); hsa04530 Tight junction - Homo sapiens (human); hsa05220 Chronic myeloid leukemia - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa04115 p53 signaling pathway - Homo sapiens (human); hsa05167 Kaposi's sarcoma-associated herpesvirus infection - Homo sapiens (human); hsa05222 Small cell lung cancer - Homo sapiens (human); hsa05162 Measles - Homo sapiens (human); hsa05225 Hepatocellular carcinoma - Homo sapiens (human); hsa05166 HTLV-I infection - Homo sapiens (human); hsa04660 T cell receptor signaling pathway - Homo sapiens (human); hsa05223 Non-small cell lung cancer - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa05219 Bladder cancer - Homo sapiens (human); hsa04934 Cushing's syndrome - Homo sapiens (human); hsa04933 AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human); hsa05203 Viral carcinogenesis - Homo sapiens (human); hsa05224 Breast cancer - Homo sapiens (human); hsa05214 Glioma - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa04110 Cell cycle - Homo sapiens (human); hsa01522 Endocrine resistance - Homo sapiens (human); hsa05161 Hepatitis B - Homo sapiens (human); hsa05218 Melanoma - Homo sapiens (human); hsa05212 Pancreatic cancer - Homo sapiens (human); ","IPR000719; IPR011009; ","Protein kinase domain; Protein kinase-like domain; \r"]
["P11908","Ribose-phosphate pyrophosphokinase 2 OS=Homo sapiens OX=9606 GN=PRPS2","PRPS2",34.769,6.5616,20.8,5,8,3,1.086,0.9,0.976,0.951,1.042,1.048,1.027,0.676,"cyto_nucl\r","GO:0031100 animal organ regeneration; GO:0042278 purine nucleoside metabolic process; GO:0009116 nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009163 nucleoside biosynthetic process; GO:0046129 purine ribonucleoside biosynthetic process; GO:0009058 biosynthetic process; GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process; GO:0009156 ribonucleoside monophosphate biosynthetic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0046390 ribose phosphate biosynthetic process; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0006753 nucleoside phosphate metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0032502 developmental process; GO:0018130 heterocycle biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0072521 purine-containing compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0032501 multicellular organismal process; GO:0009168 purine ribonucleoside monophosphate biosynthetic process; GO:0042451 purine nucleoside biosynthetic process; GO:0090407 organophosphate biosynthetic process; GO:0048513 animal organ development; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0072522 purine-containing compound biosynthetic process; GO:0044710 single-organism metabolic process; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0006164 purine nucleotide biosynthetic process; GO:0048856 anatomical structure development; GO:1901362 organic cyclic compound biosynthetic process; GO:0044707 single-multicellular organism process; GO:0016310 phosphorylation; GO:0009165 nucleotide biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0009259 ribonucleotide metabolic process; GO:0046033 AMP metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0046391 5-phosphoribose 1-diphosphate metabolic process; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009119 ribonucleoside metabolic process; GO:0009987 cellular process; GO:0009124 nucleoside monophosphate biosynthetic process; GO:0044711 single-organism biosynthetic process; GO:0048731 system development; GO:0009127 purine nucleoside monophosphate biosynthetic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0042455 ribonucleoside biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0006163 purine nucleotide metabolic process; GO:0044249 cellular biosynthetic process; GO:0046128 purine ribonucleoside metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0009152 purine ribonucleotide biosynthetic process; GO:0006793 phosphorus metabolic process; GO:1901659 glycosyl compound biosynthetic process; GO:0044767 single-organism developmental process; GO:0009260 ribonucleotide biosynthetic process; GO:0006167 AMP biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0031099 regeneration; GO:1901564 organonitrogen compound metabolic process; GO:0009123 nucleoside monophosphate metabolic process; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:1902494 catalytic complex; GO:0044421 extracellular region part; GO:0061695 transferase complex, transferring phosphorus-containing groups; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0002189 ribose phosphate diphosphokinase complex; GO:0032991 macromolecular complex; GO:1990234 transferase complex; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:1901265 nucleoside phosphate binding; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0019003 GDP binding; GO:0016301 kinase activity; GO:0016208 AMP binding; GO:0042802 identical protein binding; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043531 ADP binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0016778 diphosphotransferase activity; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0019001 guanyl nucleotide binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0000287 magnesium ion binding; GO:0004749 ribose phosphate diphosphokinase activity; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0042803 protein homodimerization activity; GO:0030246 carbohydrate binding; GO:0046872 metal ion binding; GO:0032555 purine ribonucleotide binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0036094 small molecule binding; ","K00948","PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]","hsa00230 Purine metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00030 Pentose phosphate pathway - Homo sapiens (human); hsa01230 Biosynthesis of amino acids - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); ","IPR000836; IPR029099; IPR029057; ","\"Phosphoribosyltransferase domain; Ribose-phosphate pyrophosphokinase, N-terminal domain; Phosphoribosyltransferase-like; \"\r"]
["P11940","Polyadenylate-binding protein 1 OS=Homo sapiens OX=9606 GN=PABPC1","PABPC1",70.67,118.88,28.1,20,32,13,0.883,0.926,0.816,1.12,1.105,1.18,1.297,0.0034,"nucleus\r","GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0006518 peptide metabolic process; GO:0043489 RNA stabilization; GO:0010608 posttranscriptional regulation of gene expression; GO:0009891 positive regulation of biosynthetic process; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0006396 RNA processing; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0031323 regulation of cellular metabolic process; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0031047 gene silencing by RNA; GO:0006402 mRNA catabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0016071 mRNA metabolic process; GO:0048255 mRNA stabilization; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:1902369 negative regulation of RNA catabolic process; GO:0006378 mRNA polyadenylation; GO:0044267 cellular protein metabolic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0043487 regulation of RNA stability; GO:0044270 cellular nitrogen compound catabolic process; GO:1902373 negative regulation of mRNA catabolic process; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0000375 RNA splicing, via transesterification reactions; GO:0009896 positive regulation of catabolic process; GO:0044248 cellular catabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0061013 regulation of mRNA catabolic process; GO:0008380 RNA splicing; GO:0051254 positive regulation of RNA metabolic process; GO:0043900 regulation of multi-organism process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0034248 regulation of cellular amide metabolic process; GO:0031330 negative regulation of cellular catabolic process; GO:1903311 regulation of mRNA metabolic process; GO:0051247 positive regulation of protein metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:1901564 organonitrogen compound metabolic process; GO:2000623 negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0031331 positive regulation of cellular catabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:1903312 negative regulation of mRNA metabolic process; GO:0051253 negative regulation of RNA metabolic process; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0006413 translational initiation; GO:1901361 organic cyclic compound catabolic process; GO:0006412 translation; GO:0010468 regulation of gene expression; GO:1903902 positive regulation of viral life cycle; GO:0043902 positive regulation of multi-organism process; GO:0043631 RNA polyadenylation; GO:0031326 regulation of cellular biosynthetic process; GO:0045727 positive regulation of translation; GO:0043043 peptide biosynthetic process; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0045069 regulation of viral genome replication; GO:0010605 negative regulation of macromolecule metabolic process; GO:1903313 positive regulation of mRNA metabolic process; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:0006401 RNA catabolic process; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; GO:0090304 nucleic acid metabolic process; GO:0019222 regulation of metabolic process; GO:0031123 RNA 3'-end processing; GO:0006725 cellular aromatic compound metabolic process; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0031124 mRNA 3'-end processing; GO:1900153 positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; GO:0060255 regulation of macromolecule metabolic process; GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening; GO:0061014 positive regulation of mRNA catabolic process; GO:1900151 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; GO:0009895 negative regulation of catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0045070 positive regulation of viral genome replication; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0050792 regulation of viral process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0043488 regulation of mRNA stability; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0016458 gene silencing; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0048524 positive regulation of viral process; GO:0051246 regulation of protein metabolic process; GO:0006417 regulation of translation; GO:0009057 macromolecule catabolic process; GO:0034250 positive regulation of cellular amide metabolic process; GO:0010467 gene expression; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0043604 amide biosynthetic process; GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening; GO:1903900 regulation of viral life cycle; GO:0009056 catabolic process; GO:0065007 biological regulation; GO:0046700 heterocycle catabolic process; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:1902494 catalytic complex; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043229 intracellular organelle; GO:0010494 cytoplasmic stress granule; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0005681 spliceosomal complex; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0035770 ribonucleoprotein granule; GO:0071013 catalytic step 2 spliceosome; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0008143 poly(A) binding; GO:0003723 RNA binding; GO:1901265 nucleoside phosphate binding; GO:0003730 mRNA 3'-UTR binding; GO:0090079 translation regulator activity, nucleic acid binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0070717 poly-purine tract binding; GO:0045182 translation regulator activity; GO:0003727 single-stranded RNA binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0003729 mRNA binding; GO:0008187 poly-pyrimidine tract binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0008022 protein C-terminus binding; GO:0008494 translation activator activity; GO:0008266 poly(U) RNA binding; GO:0036094 small molecule binding; ","K13126","PABPC; polyadenylate-binding protein","hsa03018 RNA degradation - Homo sapiens (human); hsa03015 mRNA surveillance pathway - Homo sapiens (human); hsa03013 RNA transport - Homo sapiens (human); ","IPR002004; IPR000504; IPR012677; IPR003954; ","\"Polyadenylate-binding protein/Hyperplastic disc protein; RNA recognition motif domain; Nucleotide-binding alpha-beta plait domain; RNA recognition motif domain, eukaryote; \"\r"]
["P12004","Proliferating cell nuclear antigen OS=Homo sapiens OX=9606 GN=PCNA","PCNA",28.768,38.328,27.2,6,8,6,0.816,0.891,0.901,1.178,1.099,1.115,1.301,0.00224,"cytoplasm\r","GO:0044700 single organism signaling; GO:1902807 negative regulation of cell cycle G1/S phase transition; GO:0065008 regulation of biological quality; GO:0048732 gland development; GO:0006266 DNA ligation; GO:0022414 reproductive process; GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion; GO:0006289 nucleotide-excision repair; GO:0009891 positive regulation of biosynthetic process; GO:0034644 cellular response to UV; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0072431 signal transduction involved in mitotic G1 DNA damage checkpoint; GO:1902403 signal transduction involved in mitotic DNA integrity checkpoint; GO:0008152 metabolic process; GO:0007507 heart development; GO:0033260 nuclear DNA replication; GO:0044093 positive regulation of molecular function; GO:0051606 detection of stimulus; GO:0044702 single organism reproductive process; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0048545 response to steroid hormone; GO:0009719 response to endogenous stimulus; GO:0019985 translesion synthesis; GO:0044770 cell cycle phase transition; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0090068 positive regulation of cell cycle process; GO:0000278 mitotic cell cycle; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0044773 mitotic DNA damage checkpoint; GO:0071214 cellular response to abiotic stimulus; GO:0051054 positive regulation of DNA metabolic process; GO:0080090 regulation of primary metabolic process; GO:2000134 negative regulation of G1/S transition of mitotic cell cycle; GO:0000302 response to reactive oxygen species; GO:0044763 single-organism cellular process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0071482 cellular response to light stimulus; GO:1903506 regulation of nucleic acid-templated transcription; GO:0010243 response to organonitrogen compound; GO:0048513 animal organ development; GO:0010948 negative regulation of cell cycle process; GO:0072413 signal transduction involved in mitotic cell cycle checkpoint; GO:0051336 regulation of hydrolase activity; GO:0080135 regulation of cellular response to stress; GO:0044710 single-organism metabolic process; GO:1902400 intracellular signal transduction involved in G1 DNA damage checkpoint; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:1901698 response to nitrogen compound; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0032200 telomere organization; GO:0006297 nucleotide-excision repair, DNA gap filling; GO:0031297 replication fork processing; GO:0006312 mitotic recombination; GO:0090305 nucleic acid phosphodiester bond hydrolysis; GO:0048609 multicellular organismal reproductive process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0030855 epithelial cell differentiation; GO:0000003 reproduction; GO:0050794 regulation of cellular process; GO:0072359 circulatory system development; GO:0016925 protein sumoylation; GO:0033554 cellular response to stress; GO:0044707 single-multicellular organism process; GO:0007346 regulation of mitotic cell cycle; GO:0006260 DNA replication; GO:0006283 transcription-coupled nucleotide-excision repair; GO:0006275 regulation of DNA replication; GO:2001020 regulation of response to DNA damage stimulus; GO:0006259 DNA metabolic process; GO:0009628 response to abiotic stimulus; GO:0044267 cellular protein metabolic process; GO:1901700 response to oxygen-containing compound; GO:0032075 positive regulation of nuclease activity; GO:0032355 response to estradiol; GO:0000731 DNA synthesis involved in DNA repair; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0080134 regulation of response to stress; GO:1903047 mitotic cell cycle process; GO:0042698 ovulation cycle; GO:0060249 anatomical structure homeostasis; GO:0006301 postreplication repair; GO:0030330 DNA damage response, signal transduction by p53 class mediator; GO:0032069 regulation of nuclease activity; GO:0046483 heterocycle metabolic process; GO:0051345 positive regulation of hydrolase activity; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:1902402 signal transduction involved in mitotic DNA damage checkpoint; GO:1901987 regulation of cell cycle phase transition; GO:0045740 positive regulation of DNA replication; GO:0009889 regulation of biosynthetic process; GO:0044819 mitotic G1/S transition checkpoint; GO:0007093 mitotic cell cycle checkpoint; GO:0070987 error-free translesion synthesis; GO:0051171 regulation of nitrogen compound metabolic process; GO:0061008 hepaticobiliary system development; GO:0007275 multicellular organism development; GO:0045787 positive regulation of cell cycle; GO:0044772 mitotic cell cycle phase transition; GO:0009416 response to light stimulus; GO:0006950 response to stress; GO:0048731 system development; GO:0072331 signal transduction by p53 class mediator; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle; GO:0008283 cell proliferation; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0006974 cellular response to DNA damage stimulus; GO:0001889 liver development; GO:0032446 protein modification by small protein conjugation; GO:0051276 chromosome organization; GO:0042542 response to hydrogen peroxide; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0032077 positive regulation of deoxyribonuclease activity; GO:0031328 positive regulation of cellular biosynthetic process; GO:0048584 positive regulation of response to stimulus; GO:0043412 macromolecule modification; GO:1902990 mitotic telomere maintenance via semi-conservative replication; GO:0000723 telomere maintenance; GO:2000045 regulation of G1/S transition of mitotic cell cycle; GO:0031100 animal organ regeneration; GO:0001101 response to acid chemical; GO:0048869 cellular developmental process; GO:0044783 G1 DNA damage checkpoint; GO:0044699 single-organism process; GO:0045005 DNA-dependent DNA replication maintenance of fidelity; GO:0009058 biosynthetic process; GO:0006282 regulation of DNA repair; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0045930 negative regulation of mitotic cell cycle; GO:0000077 DNA damage checkpoint; GO:0007154 cell communication; GO:0044774 mitotic DNA integrity checkpoint; GO:1901991 negative regulation of mitotic cell cycle phase transition; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:1902806 regulation of cell cycle G1/S phase transition; GO:0000075 cell cycle checkpoint; GO:0006979 response to oxidative stress; GO:0046686 response to cadmium ion; GO:0009314 response to radiation; GO:0034599 cellular response to oxidative stress; GO:0010035 response to inorganic substance; GO:0006261 DNA-dependent DNA replication; GO:0051726 regulation of cell cycle; GO:0070887 cellular response to chemical stimulus; GO:2001022 positive regulation of response to DNA damage stimulus; GO:0006310 DNA recombination; GO:0031571 mitotic G1 DNA damage checkpoint; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0043200 response to amino acid; GO:0060429 epithelium development; GO:0034614 cellular response to reactive oxygen species; GO:0009888 tissue development; GO:0031326 regulation of cellular biosynthetic process; GO:0031570 DNA integrity checkpoint; GO:0019725 cellular homeostasis; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0023052 signaling; GO:0051384 response to glucocorticoid; GO:0010038 response to metal ion; GO:0000722 telomere maintenance via recombination; GO:1902589 single-organism organelle organization; GO:0042221 response to chemical; GO:0006298 mismatch repair; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0051052 regulation of DNA metabolic process; GO:1902065 response to L-glutamate; GO:0065009 regulation of molecular function; GO:0042276 error-prone translesion synthesis; GO:0019222 regulation of metabolic process; GO:0036211 protein modification process; GO:0032201 telomere maintenance via semi-conservative replication; GO:0048856 anatomical structure development; GO:0072401 signal transduction involved in DNA integrity checkpoint; GO:0016043 cellular component organization; GO:0045786 negative regulation of cell cycle; GO:0072395 signal transduction involved in cell cycle checkpoint; GO:0097421 liver regeneration; GO:0006725 cellular aromatic compound metabolic process; GO:1901988 negative regulation of cell cycle phase transition; GO:0032070 regulation of deoxyribonuclease activity; GO:0044849 estrous cycle; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0045739 positive regulation of DNA repair; GO:0042769 DNA damage response, detection of DNA damage; GO:0050896 response to stimulus; GO:0033683 nucleotide-excision repair, DNA incision; GO:0070301 cellular response to hydrogen peroxide; GO:0071704 organic substance metabolic process; GO:0018205 peptidyl-lysine modification; GO:0033993 response to lipid; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:0031960 response to corticosteroid; GO:0042770 signal transduction in response to DNA damage; GO:0071897 DNA biosynthetic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0000082 G1/S transition of mitotic cell cycle; GO:0009059 macromolecule biosynthetic process; GO:0071478 cellular response to radiation; GO:0009987 cellular process; GO:0044786 cell cycle DNA replication; GO:0071156 regulation of cell cycle arrest; GO:0006355 regulation of transcription, DNA-templated; GO:0072422 signal transduction involved in DNA damage checkpoint; GO:0035556 intracellular signal transduction; GO:0044843 cell cycle G1/S phase transition; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0043085 positive regulation of catalytic activity; GO:0071548 response to dexamethasone; GO:0032504 multicellular organism reproduction; GO:0018193 peptidyl-amino acid modification; GO:0006281 DNA repair; GO:1901701 cellular response to oxygen-containing compound; GO:0009411 response to UV; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0048511 rhythmic process; GO:0044767 single-organism developmental process; GO:0071158 positive regulation of cell cycle arrest; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0022402 cell cycle process; GO:0009725 response to hormone; GO:0031099 regeneration; GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; GO:0007049 cell cycle; GO:1901654 response to ketone; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0000784 nuclear chromosome, telomeric region; GO:0000781 chromosome, telomeric region; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0005815 microtubule organizing center; GO:0005654 nucleoplasm; GO:0043626 PCNA complex; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0044454 nuclear chromosome part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0030894 replisome; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0044796 DNA polymerase processivity factor complex; GO:0044451 nucleoplasm part; GO:0032993 protein-DNA complex; GO:0043233 organelle lumen; GO:0005657 replication fork; GO:0043229 intracellular organelle; GO:0005663 DNA replication factor C complex; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005576 extracellular region; GO:0043596 nuclear replication fork; GO:0070557 PCNA-p21 complex; GO:0098687 chromosomal region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0005813 centrosome; GO:0000228 nuclear chromosome; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044428 nuclear part; ","GO:1990782 protein tyrosine kinase binding; GO:0005102 receptor binding; GO:0070182 DNA polymerase binding; GO:0003690 double-stranded DNA binding; GO:0000701 purine-specific mismatch base pair DNA N-glycosylase activity; GO:0019901 protein kinase binding; GO:0032405 MutLalpha complex binding; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0051427 hormone receptor binding; GO:0003682 chromatin binding; GO:0098772 molecular function regulator; GO:0032404 mismatch repair complex binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032135 DNA insertion or deletion binding; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0035258 steroid hormone receptor binding; GO:0032139 dinucleotide insertion or deletion binding; GO:0003684 damaged DNA binding; GO:0003677 DNA binding; GO:0030331 estrogen receptor binding; GO:0030337 DNA polymerase processivity factor activity; GO:0044877 macromolecular complex binding; GO:0019900 kinase binding; GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds; GO:0030971 receptor tyrosine kinase binding; GO:0030983 mismatched DNA binding; GO:0030234 enzyme regulator activity; GO:0000700 mismatch base pair DNA N-glycosylase activity; GO:0016798 hydrolase activity, acting on glycosyl bonds; GO:0003676 nucleic acid binding; GO:0035257 nuclear hormone receptor binding; GO:0019104 DNA N-glycosylase activity; GO:0019899 enzyme binding; GO:0035035 histone acetyltransferase binding; GO:0032403 protein complex binding; ","K04802","PCNA; proliferating cell nuclear antigen","hsa04110 Cell cycle - Homo sapiens (human); hsa05166 HTLV-I infection - Homo sapiens (human); hsa03430 Mismatch repair - Homo sapiens (human); hsa05161 Hepatitis B - Homo sapiens (human); hsa04530 Tight junction - Homo sapiens (human); hsa03420 Nucleotide excision repair - Homo sapiens (human); hsa03410 Base excision repair - Homo sapiens (human); hsa03030 DNA replication - Homo sapiens (human); ","IPR022649; IPR022648; ","\"Proliferating cell nuclear antigen, PCNA, C-terminal; Proliferating cell nuclear antigen, PCNA, N-terminal; \"\r"]
["P12074","Cytochrome c oxidase subunit 6A1, mitochondrial OS=Homo sapiens OX=9606 GN=COX6A1","COX6A1",12.155,1.8484,26.6,1,1,1,0.92,1.025,1.278,1.041,0.891,0.86,0.866,0.291,"mitochondria\r","GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0006123 mitochondrial electron transport, cytochrome c to oxygen; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0006753 nucleoside phosphate metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0044765 single-organism transport; GO:0098655 cation transmembrane transport; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006119 oxidative phosphorylation; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0006810 transport; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0065009 regulation of molecular function; GO:0022900 electron transport chain; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0098662 inorganic cation transmembrane transport; GO:0016310 phosphorylation; GO:0034220 ion transmembrane transport; GO:0006725 cellular aromatic compound metabolic process; GO:0042773 ATP synthesis coupled electron transport; GO:0009259 ribonucleotide metabolic process; GO:0022904 respiratory electron transport chain; GO:0071704 organic substance metabolic process; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0006812 cation transport; GO:0006139 nucleobase-containing compound metabolic process; GO:1902600 hydrogen ion transmembrane transport; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009119 ribonucleoside metabolic process; GO:0009987 cellular process; GO:0046034 ATP metabolic process; GO:0098660 inorganic ion transmembrane transport; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0045333 cellular respiration; GO:0006163 purine nucleotide metabolic process; GO:0006818 hydrogen transport; GO:0015992 proton transport; GO:0055085 transmembrane transport; GO:0046128 purine ribonucleoside metabolic process; GO:0006793 phosphorus metabolic process; GO:0006811 ion transport; GO:0009060 aerobic respiration; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0051179 localization; GO:0015672 monovalent inorganic cation transport; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0098803 respiratory chain complex; GO:0005751 mitochondrial respiratory chain complex IV; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0070069 cytochrome complex; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0005739 mitochondrion; GO:0005746 mitochondrial respiratory chain; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0045277 respiratory chain complex IV; GO:0031975 envelope; GO:0043234 protein complex; GO:0070469 respiratory chain; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0015075 ion transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0015077 monovalent inorganic cation transmembrane transporter activity; GO:0016676 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor; GO:0098772 molecular function regulator; GO:0016675 oxidoreductase activity, acting on a heme group of donors; GO:0015078 hydrogen ion transmembrane transporter activity; GO:0015002 heme-copper terminal oxidase activity; GO:0016491 oxidoreductase activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0009055 electron carrier activity; GO:0004129 cytochrome-c oxidase activity; GO:0030234 enzyme regulator activity; GO:0003824 catalytic activity; GO:0022890 inorganic cation transmembrane transporter activity; GO:0008324 cation transmembrane transporter activity; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; ","K02266","COX6A; cytochrome c oxidase subunit 6a","hsa04260 Cardiac muscle contraction - Homo sapiens (human); hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); "]
["P12081","Histidine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=HARS","HARS",57.41,55.445,24.4,13,19,13,0.872,0.88,0.872,1.107,1.124,1.113,1.274,7.36e-07,"cytoplasm\r","GO:0006518 peptide metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0043039 tRNA aminoacylation; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0006418 tRNA aminoacylation for protein translation; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0006412 translation; GO:0009987 cellular process; GO:0043043 peptide biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0032543 mitochondrial translation; GO:0043603 cellular amide metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0016070 RNA metabolic process; GO:0006399 tRNA metabolic process; GO:0090304 nucleic acid metabolic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0044710 single-organism metabolic process; GO:0043038 amino acid activation; GO:0019752 carboxylic acid metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0006427 histidyl-tRNA aminoacylation; GO:0006082 organic acid metabolic process; GO:0034660 ncRNA metabolic process; GO:0043436 oxoacid metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0005829 cytosol; GO:0005739 mitochondrion; GO:0044444 cytoplasmic part; ","GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds; GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0016875 ligase activity, forming carbon-oxygen bonds; GO:0016874 ligase activity; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0004821 histidine-tRNA ligase activity; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0004812 aminoacyl-tRNA ligase activity; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K01892","HARS; histidyl-tRNA synthetase [EC:6.1.1.21]","hsa00970 Aminoacyl-tRNA biosynthesis - Homo sapiens (human); ","IPR004154; IPR009068; IPR033656; IPR000738; IPR006195; ","\"Anticodon-binding; S15/NS1, RNA-binding; Histidyl-anticodon-binding; WHEP-TRS domain; Aminoacyl-tRNA synthetase, class II; \"\r"]
["P12109","Collagen alpha-1(VI) chain OS=Homo sapiens OX=9606 GN=COL6A1","COL6A1",108.53,323.31,44.2,40,170,40,1.085,1.078,1.077,0.902,0.927,0.91,0.845,3.83e-05,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:0001649 osteoblast differentiation; GO:0001101 response to acid chemical; GO:0048869 cellular developmental process; GO:0044236 multicellular organism metabolic process; GO:0044699 single-organism process; GO:0007492 endoderm development; GO:0022610 biological adhesion; GO:0008152 metabolic process; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0007155 cell adhesion; GO:0009719 response to endogenous stimulus; GO:0043170 macromolecule metabolic process; GO:0030198 extracellular matrix organization; GO:0009790 embryo development; GO:0044259 multicellular organismal macromolecule metabolic process; GO:0070887 cellular response to chemical stimulus; GO:0048598 embryonic morphogenesis; GO:0030574 collagen catabolic process; GO:0032502 developmental process; GO:0043200 response to amino acid; GO:0051716 cellular response to stimulus; GO:0009888 tissue development; GO:0071822 protein complex subunit organization; GO:0001704 formation of primary germ layer; GO:0001503 ossification; GO:0044763 single-organism cellular process; GO:0032501 multicellular organismal process; GO:0071417 cellular response to organonitrogen compound; GO:0051291 protein heterooligomerization; GO:0010243 response to organonitrogen compound; GO:0042221 response to chemical; GO:1901699 cellular response to nitrogen compound; GO:0044710 single-organism metabolic process; GO:0071230 cellular response to amino acid stimulus; GO:1901698 response to nitrogen compound; GO:0070271 protein complex biogenesis; GO:0048856 anatomical structure development; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0071310 cellular response to organic substance; GO:1901700 response to oxygen-containing compound; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0051259 protein oligomerization; GO:0007369 gastrulation; GO:0009653 anatomical structure morphogenesis; GO:0030154 cell differentiation; GO:0044243 multicellular organismal catabolic process; GO:0071229 cellular response to acid chemical; GO:0043062 extracellular structure organization; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0006461 protein complex assembly; GO:0070206 protein trimerization; GO:0001706 endoderm formation; GO:0035987 endodermal cell differentiation; GO:0044712 single-organism catabolic process; GO:0010033 response to organic substance; GO:0070208 protein heterotrimerization; GO:0043933 macromolecular complex subunit organization; GO:1901701 cellular response to oxygen-containing compound; GO:0044767 single-organism developmental process; GO:0071495 cellular response to endogenous stimulus; GO:0032963 collagen metabolic process; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0005581 collagen trimer; GO:0044422 organelle part; GO:0005765 lysosomal membrane; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0098805 whole membrane; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0005788 endoplasmic reticulum lumen; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005589 collagen type VI trimer; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0099081 supramolecular polymer; GO:0098852 lytic vacuole membrane; GO:0031012 extracellular matrix; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044432 endoplasmic reticulum part; GO:0098647 collagen beaded filament; GO:0044437 vacuolar part; GO:0005578 proteinaceous extracellular matrix; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0043234 protein complex; GO:0042383 sarcolemma; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0048407 platelet-derived growth factor binding; GO:0005515 protein binding; GO:0019838 growth factor binding; GO:0005488 binding; ","K06238","COL6A; collagen, type VI, alpha","hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa04512 ECM-receptor interaction - Homo sapiens (human); hsa04974 Protein digestion and absorption - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); ","IPR002035; ","\"von Willebrand factor, type A; \"\r"]
["P12110","Collagen alpha-2(VI) chain OS=Homo sapiens OX=9606 GN=COL6A2","COL6A2",108.58,323.31,32.1,32,159,32,1.095,1.066,1.09,0.906,0.922,0.913,0.843,6.09e-05,"extracellular\r","GO:0044085 cellular component biogenesis; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0009746 response to hexose; GO:0044236 multicellular organism metabolic process; GO:1901700 response to oxygen-containing compound; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0009749 response to glucose; GO:0071704 organic substance metabolic process; GO:0051259 protein oligomerization; GO:0022610 biological adhesion; GO:0008152 metabolic process; GO:0044243 multicellular organismal catabolic process; GO:0022607 cellular component assembly; GO:0043062 extracellular structure organization; GO:0065003 macromolecular complex assembly; GO:0007155 cell adhesion; GO:0043170 macromolecule metabolic process; GO:0030198 extracellular matrix organization; GO:0009743 response to carbohydrate; GO:0044259 multicellular organismal macromolecule metabolic process; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0030574 collagen catabolic process; GO:0070206 protein trimerization; GO:0071822 protein complex subunit organization; GO:0044712 single-organism catabolic process; GO:0044763 single-organism cellular process; GO:0010033 response to organic substance; GO:0070208 protein heterotrimerization; GO:0032501 multicellular organismal process; GO:0043933 macromolecular complex subunit organization; GO:0051291 protein heterooligomerization; GO:0042221 response to chemical; GO:0044710 single-organism metabolic process; GO:0034284 response to monosaccharide; GO:0032963 collagen metabolic process; GO:0070271 protein complex biogenesis; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0005581 collagen trimer; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005788 endoplasmic reticulum lumen; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031012 extracellular matrix; GO:0044432 endoplasmic reticulum part; GO:0005578 proteinaceous extracellular matrix; GO:0043234 protein complex; GO:0042383 sarcolemma; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ","K06238","COL6A; collagen, type VI, alpha","hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa04512 ECM-receptor interaction - Homo sapiens (human); hsa04974 Protein digestion and absorption - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); ","IPR002035; ","\"von Willebrand factor, type A; \"\r"]
["P12111","Collagen alpha-3(VI) chain OS=Homo sapiens OX=9606 GN=COL6A3","COL6A3",343.67,323.31,43.6,138,540,138,1.089,1.081,1.094,0.908,0.92,0.909,0.839,2.75e-06,"extracellular\r","GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0010951 negative regulation of endopeptidase activity; GO:0060255 regulation of macromolecule metabolic process; GO:0044236 multicellular organism metabolic process; GO:0044699 single-organism process; GO:0031324 negative regulation of cellular metabolic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0051346 negative regulation of hydrolase activity; GO:0071704 organic substance metabolic process; GO:0022610 biological adhesion; GO:0010466 negative regulation of peptidase activity; GO:0008152 metabolic process; GO:0044243 multicellular organismal catabolic process; GO:0043062 extracellular structure organization; GO:0007155 cell adhesion; GO:0061061 muscle structure development; GO:0043170 macromolecule metabolic process; GO:0030198 extracellular matrix organization; GO:0007275 multicellular organism development; GO:0044259 multicellular organismal macromolecule metabolic process; GO:0009987 cellular process; GO:0030574 collagen catabolic process; GO:0052548 regulation of endopeptidase activity; GO:0032502 developmental process; GO:0045861 negative regulation of proteolysis; GO:0080090 regulation of primary metabolic process; GO:0044712 single-organism catabolic process; GO:0048731 system development; GO:0044763 single-organism cellular process; GO:0030162 regulation of proteolysis; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0009892 negative regulation of metabolic process; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0051336 regulation of hydrolase activity; GO:0007517 muscle organ development; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0051246 regulation of protein metabolic process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0044767 single-organism developmental process; GO:0032963 collagen metabolic process; GO:0065009 regulation of molecular function; GO:0051248 negative regulation of protein metabolic process; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0052547 regulation of peptidase activity; GO:0009056 catabolic process; GO:0048856 anatomical structure development; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0005581 collagen trimer; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005788 endoplasmic reticulum lumen; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005589 collagen type VI trimer; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0099081 supramolecular polymer; GO:0031012 extracellular matrix; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044432 endoplasmic reticulum part; GO:0098647 collagen beaded filament; GO:0005578 proteinaceous extracellular matrix; GO:0043234 protein complex; GO:0042383 sarcolemma; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0004867 serine-type endopeptidase inhibitor activity; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0030414 peptidase inhibitor activity; GO:0061134 peptidase regulator activity; GO:0005515 protein binding; GO:0061135 endopeptidase regulator activity; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0004866 endopeptidase inhibitor activity; ","K06238","COL6A; collagen, type VI, alpha","hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa04512 ECM-receptor interaction - Homo sapiens (human); hsa04974 Protein digestion and absorption - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); ","IPR013783; IPR003961; IPR002223; IPR002035; ","\"Immunoglobulin-like fold; Fibronectin type III; Pancreatic trypsin inhibitor Kunitz domain; von Willebrand factor, type A; \"\r"]
["P12235","ADP/ATP translocase 1 OS=Homo sapiens OX=9606 GN=SLC25A4","SLC25A4",33.064,9.1082,34.9,12,24,3,0.908,1.137,1.253,0.905,0.943,0.869,0.824,0.132,"mitochondria\r","GO:0010941 regulation of cell death; GO:0060544 regulation of necroptotic process; GO:0065008 regulation of biological quality; GO:0006839 mitochondrial transport; GO:0050796 regulation of insulin secretion; GO:0023051 regulation of signaling; GO:0051046 regulation of secretion; GO:0044699 single-organism process; GO:0015868 purine ribonucleotide transport; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0051503 adenine nucleotide transport; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0010646 regulation of cell communication; GO:0006091 generation of precursor metabolites and energy; GO:0060546 negative regulation of necroptotic process; GO:0032879 regulation of localization; GO:0015931 nucleobase-containing compound transport; GO:0007005 mitochondrion organization; GO:0006915 apoptotic process; GO:0090559 regulation of membrane permeability; GO:0044419 interspecies interaction between organisms; GO:0044765 single-organism transport; GO:0015851 nucleobase transport; GO:0060547 negative regulation of necrotic cell death; GO:0006862 nucleotide transport; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:1903530 regulation of secretion by cell; GO:0051704 multi-organism process; GO:0015858 nucleoside transport; GO:0006810 transport; GO:1902589 single-organism organelle organization; GO:0015748 organophosphate ester transport; GO:0050789 regulation of biological process; GO:0046883 regulation of hormone secretion; GO:0010817 regulation of hormone levels; GO:0051223 regulation of protein transport; GO:0060548 negative regulation of cell death; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0043069 negative regulation of programmed cell death; GO:0015867 ATP transport; GO:0007006 mitochondrial membrane organization; GO:0043067 regulation of programmed cell death; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0070201 regulation of establishment of protein localization; GO:0002791 regulation of peptide secretion; GO:1902578 single-organism localization; GO:0046902 regulation of mitochondrial membrane permeability; GO:0016032 viral process; GO:1901264 carbohydrate derivative transport; GO:0032880 regulation of protein localization; GO:0000002 mitochondrial genome maintenance; GO:0050708 regulation of protein secretion; GO:0009987 cellular process; GO:0010939 regulation of necrotic cell death; GO:0090087 regulation of peptide transport; GO:0008637 apoptotic mitochondrial changes; GO:0015865 purine nucleotide transport; GO:0051049 regulation of transport; GO:0044802 single-organism membrane organization; GO:0071702 organic substance transport; GO:0006820 anion transport; GO:0055085 transmembrane transport; GO:0015711 organic anion transport; GO:0015853 adenine transport; GO:0008219 cell death; GO:0006996 organelle organization; GO:0006811 ion transport; GO:0061024 membrane organization; GO:0090276 regulation of peptide hormone secretion; GO:0006863 purine nucleobase transport; GO:0012501 programmed cell death; GO:0051179 localization; GO:0015866 ADP transport; GO:0071705 nitrogen compound transport; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0031226 intrinsic component of plasma membrane; GO:0044429 mitochondrial part; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0005740 mitochondrial envelope; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0043209 myelin sheath; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0031975 envelope; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0022804 active transmembrane transporter activity; GO:0015291 secondary active transmembrane transporter activity; GO:0015216 purine nucleotide transmembrane transporter activity; GO:1901505 carbohydrate derivative transporter activity; GO:0005345 purine nucleobase transmembrane transporter activity; GO:0015075 ion transmembrane transporter activity; GO:0015207 adenine transmembrane transporter activity; GO:0000295 adenine nucleotide transmembrane transporter activity; GO:0015301 anion:anion antiporter activity; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0005471 ATP:ADP antiporter activity; GO:0015297 antiporter activity; GO:0015932 nucleobase-containing compound transmembrane transporter activity; GO:0099516 ion antiporter activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0015205 nucleobase transmembrane transporter activity; GO:0015215 nucleotide transmembrane transporter activity; GO:0015217 ADP transmembrane transporter activity; GO:0005488 binding; GO:0005346 purine ribonucleotide transmembrane transporter activity; GO:0015211 purine nucleoside transmembrane transporter activity; GO:0005347 ATP transmembrane transporter activity; GO:0005337 nucleoside transmembrane transporter activity; GO:0015605 organophosphate ester transmembrane transporter activity; GO:0008514 organic anion transmembrane transporter activity; GO:0008509 anion transmembrane transporter activity; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; ","K05863","SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31","hsa04218 Cellular senescence - Homo sapiens (human); hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human); hsa04217 Necroptosis - Homo sapiens (human); hsa04020 Calcium signaling pathway - Homo sapiens (human); hsa05166 HTLV-I infection - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa05164 Influenza A - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); ","IPR023395; ","Mitochondrial carrier domain; \r"]
["P12259","Coagulation factor V OS=Homo sapiens OX=9606 GN=F5","F5",251.7,2.7578,1,2,2,2,0.874,1.039,0.739,1.135,1.072,1.141,1.262,0.0732,"extracellular\r","GO:0044085 cellular component biogenesis; GO:0006901 vesicle coating; GO:0048207 vesicle targeting, rough ER to cis-Golgi; GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0048208 COPII vesicle coating; GO:0044699 single-organism process; GO:0051234 establishment of localization; GO:0009611 response to wounding; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0048199 vesicle targeting, to, from or within Golgi; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0033273 response to vitamin; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0051650 establishment of vesicle localization; GO:0071822 protein complex subunit organization; GO:0030168 platelet activation; GO:0044763 single-organism cellular process; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:0042221 response to chemical; GO:0032940 secretion by cell; GO:0050817 coagulation; GO:0003013 circulatory system process; GO:0070271 protein complex biogenesis; GO:0051640 organelle localization; GO:0044707 single-multicellular organism process; GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:1901700 response to oxygen-containing compound; GO:0048193 Golgi vesicle transport; GO:0002576 platelet degranulation; GO:0006903 vesicle targeting; GO:0050896 response to stimulus; GO:0032571 response to vitamin K; GO:0007599 hemostasis; GO:0071704 organic substance metabolic process; GO:0009991 response to extracellular stimulus; GO:1902578 single-organism localization; GO:0051648 vesicle localization; GO:0008015 blood circulation; GO:0006508 proteolysis; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0003008 system process; GO:0050878 regulation of body fluid levels; GO:0006950 response to stress; GO:0090114 COPII-coated vesicle budding; GO:0016192 vesicle-mediated transport; GO:0016050 vesicle organization; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0007584 response to nutrient; GO:0051656 establishment of organelle localization; GO:0043933 macromolecular complex subunit organization; GO:0051641 cellular localization; GO:0045055 regulated exocytosis; GO:0042060 wound healing; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0006900 membrane budding; GO:0001775 cell activation; GO:0031667 response to nutrient levels; GO:0051179 localization; GO:0006888 ER to Golgi vesicle-mediated transport; GO:1901654 response to ketone; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; GO:0006887 exocytosis; ","GO:0034774 secretory granule lumen; GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005788 endoplasmic reticulum lumen; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0030134 ER to Golgi transport vesicle; GO:0012505 endomembrane system; GO:0030135 coated vesicle; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0044432 endoplasmic reticulum part; GO:0005793 endoplasmic reticulum-Golgi intermediate compartment; GO:0031093 platelet alpha granule lumen; GO:0031091 platelet alpha granule; GO:0030133 transport vesicle; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0008233 peptidase activity; GO:0008236 serine-type peptidase activity; GO:0043167 ion binding; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0005507 copper ion binding; GO:0004175 endopeptidase activity; GO:0004252 serine-type endopeptidase activity; GO:0046914 transition metal ion binding; GO:0017171 serine hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; ","K03902","F5; coagulation factor V (labile factor)","hsa04610 Complement and coagulation cascades - Homo sapiens (human); ","IPR000421; IPR008972; IPR011707; IPR008979; ","\"Coagulation factor 5/8 C-terminal domain; Cupredoxin; Multicopper oxidase, type 3; Galactose-binding domain-like; \"\r"]
["P12268","Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2","IMPDH2",55.804,81.46,14.4,5,7,5,0.901,0.819,0.867,1.176,1.138,1.188,1.354,5.8E-4,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0009116 nucleoside metabolic process; GO:0045321 leukocyte activation; GO:0009163 nucleoside biosynthetic process; GO:0046129 purine ribonucleoside biosynthetic process; GO:0071345 cellular response to cytokine stimulus; GO:0044237 cellular metabolic process; GO:0046390 ribose phosphate biosynthetic process; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:1901068 guanosine-containing compound metabolic process; GO:0065003 macromolecular complex assembly; GO:0019693 ribose phosphate metabolic process; GO:0009145 purine nucleoside triphosphate biosynthetic process; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0018130 heterocycle biosynthetic process; GO:0009206 purine ribonucleoside triphosphate biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0071353 cellular response to interleukin-4; GO:0032501 multicellular organismal process; GO:0009168 purine ribonucleoside monophosphate biosynthetic process; GO:0006810 transport; GO:0090407 organophosphate biosynthetic process; GO:0048513 animal organ development; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0009126 purine nucleoside monophosphate metabolic process; GO:0006164 purine nucleotide biosynthetic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0009201 ribonucleoside triphosphate biosynthetic process; GO:0044707 single-multicellular organism process; GO:0002283 neutrophil activation involved in immune response; GO:0051260 protein homooligomerization; GO:0009259 ribonucleotide metabolic process; GO:0051259 protein oligomerization; GO:0001654 eye development; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:1901135 carbohydrate derivative metabolic process; GO:0007275 multicellular organism development; GO:0070670 response to interleukin-4; GO:0009119 ribonucleoside metabolic process; GO:0006461 protein complex assembly; GO:0044711 single-organism biosynthetic process; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0008283 cell proliferation; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0006177 GMP biosynthetic process; GO:0044238 primary metabolic process; GO:0042455 ribonucleoside biosynthetic process; GO:0002263 cell activation involved in immune response; GO:1901576 organic substance biosynthetic process; GO:0006163 purine nucleotide metabolic process; GO:0045055 regulated exocytosis; GO:0006793 phosphorus metabolic process; GO:0009260 ribonucleotide biosynthetic process; GO:0001775 cell activation; GO:0019637 organophosphate metabolic process; GO:0051179 localization; GO:0006955 immune response; GO:0007423 sensory organ development; GO:0006887 exocytosis; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0009156 ribonucleoside monophosphate biosynthetic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0022607 cellular component assembly; GO:0051262 protein tetramerization; GO:0006753 nucleoside phosphate metabolic process; GO:1901070 guanosine-containing compound biosynthetic process; GO:0070887 cellular response to chemical stimulus; GO:0006183 GTP biosynthetic process; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:0032943 mononuclear cell proliferation; GO:0046037 GMP metabolic process; GO:0071822 protein complex subunit organization; GO:0034097 response to cytokine; GO:0055114 oxidation-reduction process; GO:0002446 neutrophil mediated immunity; GO:1901360 organic cyclic compound metabolic process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0042451 purine nucleoside biosynthetic process; GO:0042221 response to chemical; GO:0072522 purine-containing compound biosynthetic process; GO:0032940 secretion by cell; GO:0070661 leukocyte proliferation; GO:1901657 glycosyl compound metabolic process; GO:0043299 leukocyte degranulation; GO:0070271 protein complex biogenesis; GO:0048856 anatomical structure development; GO:0046039 GTP metabolic process; GO:0016043 cellular component organization; GO:0043010 camera-type eye development; GO:0009165 nucleotide biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0002252 immune effector process; GO:0009142 nucleoside triphosphate biosynthetic process; GO:0071310 cellular response to organic substance; GO:1901566 organonitrogen compound biosynthetic process; GO:0046651 lymphocyte proliferation; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0051289 protein homotetramerization; GO:0034641 cellular nitrogen compound metabolic process; GO:0036230 granulocyte activation; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0060041 retina development in camera-type eye; GO:0009124 nucleoside monophosphate biosynthetic process; GO:0009127 purine nucleoside monophosphate biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0046649 lymphocyte activation; GO:0043312 neutrophil degranulation; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0002366 leukocyte activation involved in immune response; GO:0046128 purine ribonucleoside metabolic process; GO:0042119 neutrophil activation; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0009152 purine ribonucleotide biosynthetic process; GO:0044767 single-organism developmental process; GO:1901659 glycosyl compound biosynthetic process; GO:0009150 purine ribonucleotide metabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0034774 secretory granule lumen; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044438 microbody part; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0005778 peroxisomal membrane; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0042579 microbody; GO:0098805 whole membrane; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0031903 microbody membrane; GO:0044439 peroxisomal part; GO:0098588 bounding membrane of organelle; GO:0005777 peroxisome; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0003677 DNA binding; GO:0003723 RNA binding; GO:1901265 nucleoside phosphate binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0016491 oxidoreductase activity; GO:0016614 oxidoreductase activity, acting on CH-OH group of donors; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; GO:0003824 catalytic activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0003938 IMP dehydrogenase activity; GO:0036094 small molecule binding; ","K00088","IMPDH; IMP dehydrogenase [EC:1.1.1.205]","hsa00230 Purine metabolism - Homo sapiens (human); hsa00983 Drug metabolism - other enzymes - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR001093; IPR013785; IPR000644; ","IMP dehydrogenase/GMP reductase; Aldolase-type TIM barrel; CBS domain; \r"]
["P12270","Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR","TPR",267.29,187.17,15.5,35,39,35,0.97,0.989,0.996,1.009,1.02,1.009,1.028,0.0332,"nucleus\r","GO:0050658 RNA transport; GO:0044700 single organism signaling; GO:0010608 posttranscriptional regulation of gene expression; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:1905269 positive regulation of chromatin organization; GO:0033048 negative regulation of mitotic sister chromatid segregation; GO:1902583 multi-organism intracellular transport; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0031577 spindle checkpoint; GO:0051784 negative regulation of nuclear division; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0051493 regulation of cytoskeleton organization; GO:0090068 positive regulation of cell cycle process; GO:0006606 protein import into nucleus; GO:0051051 negative regulation of transport; GO:0007077 mitotic nuclear envelope disassembly; GO:0051716 cellular response to stimulus; GO:0000278 mitotic cell cycle; GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint; GO:1901673 regulation of mitotic spindle assembly; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0034249 negative regulation of cellular amide metabolic process; GO:0051985 negative regulation of chromosome segregation; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0006611 protein export from nucleus; GO:0051704 multi-organism process; GO:0032886 regulation of microtubule-based process; GO:0006810 transport; GO:0000165 MAPK cascade; GO:0080135 regulation of cellular response to stress; GO:0045931 positive regulation of mitotic cell cycle; GO:0046825 regulation of protein export from nucleus; GO:0031047 gene silencing by RNA; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0051223 regulation of protein transport; GO:0006913 nucleocytoplasmic transport; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0042307 positive regulation of protein import into nucleus; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0016925 protein sumoylation; GO:0016310 phosphorylation; GO:0031990 mRNA export from nucleus in response to heat stress; GO:0051028 mRNA transport; GO:0045947 negative regulation of translational initiation; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0045892 negative regulation of transcription, DNA-templated; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0051081 nuclear envelope disassembly; GO:0009889 regulation of biosynthetic process; GO:0090232 positive regulation of spindle checkpoint; GO:0044744 protein targeting to nucleus; GO:1902580 single-organism cellular localization; GO:0034613 cellular protein localization; GO:0023014 signal transduction by protein phosphorylation; GO:0006950 response to stress; GO:0006403 RNA localization; GO:0010033 response to organic substance; GO:1901576 organic substance biosynthetic process; GO:0034248 regulation of cellular amide metabolic process; GO:0044766 multi-organism transport; GO:1900182 positive regulation of protein localization to nucleus; GO:0033046 negative regulation of sister chromatid segregation; GO:0009890 negative regulation of biosynthetic process; GO:2001251 negative regulation of chromosome organization; GO:0006409 tRNA export from nucleus; GO:0032446 protein modification by small protein conjugation; GO:0010965 regulation of mitotic sister chromatid separation; GO:0006996 organelle organization; GO:0000280 nuclear division; GO:0043412 macromolecule modification; GO:1903827 regulation of cellular protein localization; GO:0031445 regulation of heterochromatin assembly; GO:0010256 endomembrane system organization; GO:0072594 establishment of protein localization to organelle; GO:0017038 protein import; GO:0007067 mitotic nuclear division; GO:0044699 single-organism process; GO:0051168 nuclear export; GO:0009058 biosynthetic process; GO:0051253 negative regulation of RNA metabolic process; GO:0030071 regulation of mitotic metaphase/anaphase transition; GO:0006796 phosphate-containing compound metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0042306 regulation of protein import into nucleus; GO:0045930 negative regulation of mitotic cell cycle; GO:0007165 signal transduction; GO:0051783 regulation of nuclear division; GO:0046824 positive regulation of nucleocytoplasmic transport; GO:0033036 macromolecule localization; GO:0010827 regulation of glucose transport; GO:0051726 regulation of cell cycle; GO:0034097 response to cytokine; GO:0031326 regulation of cellular biosynthetic process; GO:0045841 negative regulation of mitotic metaphase/anaphase transition; GO:0023052 signaling; GO:0006404 RNA import into nucleus; GO:0010605 negative regulation of macromolecule metabolic process; GO:0071166 ribonucleoprotein complex localization; GO:1902582 single-organism intracellular transport; GO:0030397 membrane disassembly; GO:0010638 positive regulation of organelle organization; GO:1902679 negative regulation of RNA biosynthetic process; GO:1900180 regulation of protein localization to nucleus; GO:1900034 regulation of cellular response to heat; GO:0019083 viral transcription; GO:0036211 protein modification process; GO:1901978 positive regulation of cell cycle checkpoint; GO:0051222 positive regulation of protein transport; GO:0016043 cellular component organization; GO:1902579 multi-organism localization; GO:0045786 negative regulation of cell cycle; GO:1901988 negative regulation of cell cycle phase transition; GO:1903829 positive regulation of cellular protein localization; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0048285 organelle fission; GO:0019058 viral life cycle; GO:1904589 regulation of protein import; GO:0035457 cellular response to interferon-alpha; GO:0071174 mitotic spindle checkpoint; GO:0071704 organic substance metabolic process; GO:0006468 protein phosphorylation; GO:0016032 viral process; GO:0019080 viral gene expression; GO:0006886 intracellular protein transport; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0051983 regulation of chromosome segregation; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0035556 intracellular signal transduction; GO:0051049 regulation of transport; GO:0044802 single-organism membrane organization; GO:0033043 regulation of organelle organization; GO:1902099 regulation of metaphase/anaphase transition of cell cycle; GO:0046832 negative regulation of RNA export from nucleus; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0018193 peptidyl-amino acid modification; GO:0090169 regulation of spindle assembly; GO:0071426 ribonucleoprotein complex export from nucleus; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0051170 nuclear import; GO:0051248 negative regulation of protein metabolic process; GO:0010467 gene expression; GO:0031327 negative regulation of cellular biosynthetic process; GO:0022402 cell cycle process; GO:0034504 protein localization to nucleus; GO:0044089 positive regulation of cellular component biogenesis; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:1903533 regulation of protein targeting; GO:0051169 nuclear transport; GO:0071345 cellular response to cytokine stimulus; GO:0015031 protein transport; GO:1902100 negative regulation of metaphase/anaphase transition of cell cycle; GO:0000189 MAPK import into nucleus; GO:0032879 regulation of localization; GO:0015931 nucleobase-containing compound transport; GO:0009408 response to heat; GO:0009719 response to endogenous stimulus; GO:0070848 response to growth factor; GO:0032387 negative regulation of intracellular transport; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0033365 protein localization to organelle; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0008104 protein localization; GO:0044419 interspecies interaction between organisms; GO:0075733 intracellular transport of virus; GO:0046823 negative regulation of nucleocytoplasmic transport; GO:0051031 tRNA transport; GO:0044765 single-organism transport; GO:0018130 heterocycle biosynthetic process; GO:1905818 regulation of chromosome separation; GO:0007088 regulation of mitotic nuclear division; GO:0000122 negative regulation of transcription from RNA polymerase II promoter; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:1905819 negative regulation of chromosome separation; GO:0010948 negative regulation of cell cycle process; GO:0001672 regulation of chromatin assembly or disassembly; GO:0032269 negative regulation of cellular protein metabolic process; GO:0044710 single-organism metabolic process; GO:2001252 positive regulation of chromosome organization; GO:0006464 cellular protein modification process; GO:0051301 cell division; GO:1901362 organic cyclic compound biosynthetic process; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0033554 cellular response to stress; GO:0007346 regulation of mitotic cell cycle; GO:0032239 regulation of nucleobase-containing compound transport; GO:0009628 response to abiotic stimulus; GO:1902593 single-organism nuclear import; GO:0044267 cellular protein metabolic process; GO:0017148 negative regulation of translation; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:0051236 establishment of RNA localization; GO:0060341 regulation of cellular localization; GO:1902578 single-organism localization; GO:0019438 aromatic compound biosynthetic process; GO:1901987 regulation of cell cycle phase transition; GO:0007093 mitotic cell cycle checkpoint; GO:0051171 regulation of nitrogen compound metabolic process; GO:0032880 regulation of protein localization; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0045787 positive regulation of cell cycle; GO:0010847 regulation of chromatin assembly; GO:0071173 spindle assembly checkpoint; GO:0046794 transport of virus; GO:0006405 RNA export from nucleus; GO:1902275 regulation of chromatin organization; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0071702 organic substance transport; GO:0032240 negative regulation of nucleobase-containing compound transport; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0033044 regulation of chromosome organization; GO:0045184 establishment of protein localization; GO:0090224 regulation of spindle organization; GO:0046822 regulation of nucleocytoplasmic transport; GO:1904951 positive regulation of establishment of protein localization; GO:0006793 phosphorus metabolic process; GO:0061024 membrane organization; GO:0051179 localization; GO:1904591 positive regulation of protein import; GO:0046831 regulation of RNA export from nucleus; GO:0051129 negative regulation of cellular component organization; GO:1902581 multi-organism cellular localization; GO:0044764 multi-organism cellular process; GO:0060236 regulation of mitotic spindle organization; GO:1902115 regulation of organelle assembly; GO:0071431 tRNA-containing ribonucleoprotein complex export from nucleus; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0051130 positive regulation of cellular component organization; GO:0071427 mRNA-containing ribonucleoprotein complex export from nucleus; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:1901991 negative regulation of mitotic cell cycle phase transition; GO:0050657 nucleic acid transport; GO:0000075 cell cycle checkpoint; GO:0070887 cellular response to chemical stimulus; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0010468 regulation of gene expression; GO:0033045 regulation of sister chromatid segregation; GO:0071822 protein complex subunit organization; GO:0006999 nuclear pore organization; GO:0007094 mitotic spindle assembly checkpoint; GO:0033047 regulation of mitotic sister chromatid segregation; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0032386 regulation of intracellular transport; GO:0070647 protein modification by small protein conjugation or removal; GO:0051050 positive regulation of transport; GO:0016070 RNA metabolic process; GO:0010639 negative regulation of organelle organization; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0031453 positive regulation of heterochromatin assembly; GO:0090304 nucleic acid metabolic process; GO:0034605 cellular response to heat; GO:1903504 regulation of mitotic spindle checkpoint; GO:0019222 regulation of metabolic process; GO:0045839 negative regulation of mitotic nuclear division; GO:0090231 regulation of spindle checkpoint; GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint; GO:0006997 nucleus organization; GO:0006725 cellular aromatic compound metabolic process; GO:0090316 positive regulation of intracellular protein transport; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044087 regulation of cellular component biogenesis; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:2000816 negative regulation of mitotic sister chromatid separation; GO:0070201 regulation of establishment of protein localization; GO:0006998 nuclear envelope organization; GO:0018205 peptidyl-lysine modification; GO:0009266 response to temperature stimulus; GO:0033157 regulation of intracellular protein transport; GO:0009987 cellular process; GO:0006406 mRNA export from nucleus; GO:0070507 regulation of microtubule cytoskeleton organization; GO:1901976 regulation of cell cycle checkpoint; GO:0070849 response to epidermal growth factor; GO:0032388 positive regulation of intracellular transport; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045799 positive regulation of chromatin assembly or disassembly; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0051641 cellular localization; GO:0046827 positive regulation of protein export from nucleus; GO:0070727 cellular macromolecule localization; GO:0016458 gene silencing; GO:0006417 regulation of translation; GO:0051246 regulation of protein metabolic process; GO:0035455 response to interferon-alpha; GO:0006446 regulation of translational initiation; GO:0022411 cellular component disassembly; GO:0051128 regulation of cellular component organization; GO:0071705 nitrogen compound transport; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0019898 extrinsic component of membrane; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0044427 chromosomal part; GO:0072686 mitotic spindle; GO:0005856 cytoskeleton; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0031965 nuclear membrane; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0043227 membrane-bounded organelle; GO:0000776 kinetochore; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005643 nuclear pore; GO:0005635 nuclear envelope; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0042405 nuclear inclusion body; GO:0016234 inclusion body; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0044615 nuclear pore nuclear basket; GO:0030286 dynein complex; GO:0005875 microtubule associated complex; GO:0005868 cytoplasmic dynein complex; GO:0005819 spindle; GO:0098687 chromosomal region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0031975 envelope; GO:0000775 chromosome, centromeric region; GO:0034399 nuclear periphery; GO:0043234 protein complex; GO:0044428 nuclear part; ","GO:0070840 dynein complex binding; GO:0003723 RNA binding; GO:0031072 heat shock protein binding; GO:0005487 nucleocytoplasmic transporter activity; GO:0019901 protein kinase binding; GO:0044877 macromolecular complex binding; GO:0046983 protein dimerization activity; GO:0015631 tubulin binding; GO:0051019 mitogen-activated protein kinase binding; GO:0005515 protein binding; GO:0003682 chromatin binding; GO:0019900 kinase binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0003729 mRNA binding; GO:0008092 cytoskeletal protein binding; GO:0042802 identical protein binding; GO:0005488 binding; GO:0042803 protein homodimerization activity; GO:0003676 nucleic acid binding; GO:0019899 enzyme binding; GO:0005215 transporter activity; GO:0032403 protein complex binding; ","K09291","TPR; nucleoprotein TPR","hsa05216 Thyroid cancer - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa03013 RNA transport - Homo sapiens (human); ","IPR015866; IPR012929; ","\"Serine-tRNA synthetase, type1, N-terminal; Nucleoprotein TPR/MLP1; \"\r"]
["P12273","Prolactin-inducible protein OS=Homo sapiens OX=9606 GN=PIP","PIP",16.572,46.1,34.2,4,12,4,1.226,1.206,1.227,0.836,0.809,0.736,0.651,7.92E-3,"extracellular\r","GO:0050794 regulation of cellular process; GO:0009593 detection of chemical stimulus; GO:0044707 single-multicellular organism process; GO:0070228 regulation of lymphocyte apoptotic process; GO:0065008 regulation of biological quality; GO:0010941 regulation of cell death; GO:0043069 negative regulation of programmed cell death; GO:0060255 regulation of macromolecule metabolic process; GO:0043067 regulation of programmed cell death; GO:0044699 single-organism process; GO:0050913 sensory perception of bitter taste; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0050877 neurological system process; GO:0048871 multicellular organismal homeostasis; GO:0060249 anatomical structure homeostasis; GO:0071704 organic substance metabolic process; GO:0051234 establishment of localization; GO:0050909 sensory perception of taste; GO:0042592 homeostatic process; GO:0008152 metabolic process; GO:0009893 positive regulation of metabolic process; GO:0043066 negative regulation of apoptotic process; GO:0010628 positive regulation of gene expression; GO:0051606 detection of stimulus; GO:0007606 sensory perception of chemical stimulus; GO:0006508 proteolysis; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0070232 regulation of T cell apoptotic process; GO:0050906 detection of stimulus involved in sensory perception; GO:0010468 regulation of gene expression; GO:0007600 sensory perception; GO:0003008 system process; GO:0070229 negative regulation of lymphocyte apoptotic process; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0070233 negative regulation of T cell apoptotic process; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:0055085 transmembrane transport; GO:2000106 regulation of leukocyte apoptotic process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0001895 retina homeostasis; GO:0050907 detection of chemical stimulus involved in sensory perception; GO:0001894 tissue homeostasis; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0002682 regulation of immune system process; GO:0051179 localization; GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste; GO:0060548 negative regulation of cell death; GO:2000107 negative regulation of leukocyte apoptotic process; GO:0042981 regulation of apoptotic process; GO:0050912 detection of chemical stimulus involved in sensory perception of taste; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0016324 apical plasma membrane; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0098590 plasma membrane region; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0045177 apical part of cell; ","GO:0008233 peptidase activity; GO:0019865 immunoglobulin binding; GO:0044877 macromolecular complex binding; GO:0046983 protein dimerization activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0004175 endopeptidase activity; GO:0097367 carbohydrate derivative binding; GO:0008092 cytoskeletal protein binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0004190 aspartic-type endopeptidase activity; GO:0003779 actin binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0070001 aspartic-type peptidase activity; GO:0001948 glycoprotein binding; GO:0019864 IgG binding; GO:0032403 protein complex binding; ",{"$nulls":3},"IPR014756; ","Immunoglobulin E-set; \r"]
["P12277","Creatine kinase B-type OS=Homo sapiens OX=9606 GN=CKB","CKB",42.644,323.31,60.4,15,35,15,1.162,1.162,1.177,0.83,0.857,0.849,0.724,3.24e-06,"cytoplasm\r","GO:0044707 single-multicellular organism process; GO:0016310 phosphorylation; GO:0065008 regulation of biological quality; GO:0007420 brain development; GO:0030644 cellular chloride ion homeostasis; GO:0044699 single-organism process; GO:0030320 cellular monovalent inorganic anion homeostasis; GO:0044237 cellular metabolic process; GO:0055082 cellular chemical homeostasis; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0048857 neural nucleus development; GO:0021762 substantia nigra development; GO:0042592 homeostatic process; GO:0030002 cellular anion homeostasis; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0006575 cellular modified amino acid metabolic process; GO:0060322 head development; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0030902 hindbrain development; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0030901 midbrain development; GO:0050801 ion homeostasis; GO:0048731 system development; GO:0044281 small molecule metabolic process; GO:0098771 inorganic ion homeostasis; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:0019725 cellular homeostasis; GO:0055083 monovalent inorganic anion homeostasis; GO:0055081 anion homeostasis; GO:0006600 creatine metabolic process; GO:0055064 chloride ion homeostasis; GO:1901605 alpha-amino acid metabolic process; GO:0044238 primary metabolic process; GO:0032501 multicellular organismal process; GO:0021549 cerebellum development; GO:0048513 animal organ development; GO:0006873 cellular ion homeostasis; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0044767 single-organism developmental process; GO:0007417 central nervous system development; GO:0019752 carboxylic acid metabolic process; GO:0022037 metencephalon development; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:0043436 oxoacid metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0030425 dendrite; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0042995 cell projection; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0043025 neuronal cell body; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0036477 somatodendritic compartment; GO:0043209 myelin sheath; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0044297 cell body; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0004111 creatine kinase activity; GO:0031625 ubiquitin protein ligase binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0016775 phosphotransferase activity, nitrogenous group as acceptor; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016301 kinase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0016740 transferase activity; GO:0019899 enzyme binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K00933","E2.7.3.2; creatine kinase [EC:2.7.3.2]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00330 Arginine and proline metabolism - Homo sapiens (human); ","IPR022413; IPR014746; IPR022414; ","\"ATP:guanido phosphotransferase, N-terminal; Glutamine synthetase/guanido kinase, catalytic domain; ATP:guanido phosphotransferase, catalytic domain; \"\r"]
["P12429","Annexin A3 OS=Homo sapiens OX=9606 GN=ANXA3","ANXA3",36.375,89.302,48,14,20,14,1.02,0.976,1.044,1.001,0.997,0.977,0.979,0.371,"cytoplasm\r","GO:0030335 positive regulation of cell migration; GO:0045321 leukocyte activation; GO:0021766 hippocampus development; GO:0007420 brain development; GO:0098542 defense response to other organism; GO:0010594 regulation of endothelial cell migration; GO:0009607 response to biotic stimulus; GO:0021537 telencephalon development; GO:0009605 response to external stimulus; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0048545 response to steroid hormone; GO:1904018 positive regulation of vasculature development; GO:0009719 response to endogenous stimulus; GO:0070848 response to growth factor; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0007399 nervous system development; GO:0014070 response to organic cyclic compound; GO:0002443 leukocyte mediated immunity; GO:0010632 regulation of epithelial cell migration; GO:0080090 regulation of primary metabolic process; GO:0051054 positive regulation of DNA metabolic process; GO:0044763 single-organism cellular process; GO:0051272 positive regulation of cellular component movement; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0006810 transport; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0050790 regulation of catalytic activity; GO:0051090 regulation of sequence-specific DNA binding transcription factor activity; GO:0007417 central nervous system development; GO:0010604 positive regulation of macromolecule metabolic process; GO:0045765 regulation of angiogenesis; GO:0051094 positive regulation of developmental process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0002283 neutrophil activation involved in immune response; GO:2000147 positive regulation of cell motility; GO:0051239 regulation of multicellular organismal process; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0009889 regulation of biosynthetic process; GO:2000145 regulation of cell motility; GO:0051171 regulation of nitrogen compound metabolic process; GO:0030900 forebrain development; GO:0007275 multicellular organism development; GO:0009617 response to bacterium; GO:0006950 response to stress; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0030334 regulation of cell migration; GO:0010033 response to organic substance; GO:0002263 cell activation involved in immune response; GO:0045055 regulated exocytosis; GO:0031325 positive regulation of cellular metabolic process; GO:0001775 cell activation; GO:0051179 localization; GO:0006955 immune response; GO:0050793 regulation of developmental process; GO:0006887 exocytosis; GO:0031100 animal organ regeneration; GO:0040017 positive regulation of locomotion; GO:0044699 single-organism process; GO:0021761 limbic system development; GO:0006909 phagocytosis; GO:0051234 establishment of localization; GO:2001141 regulation of RNA biosynthetic process; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0060322 head development; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0002446 neutrophil mediated immunity; GO:0048522 positive regulation of cellular process; GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity; GO:0002444 myeloid leukocyte mediated immunity; GO:0051384 response to glucocorticoid; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0051052 regulation of DNA metabolic process; GO:0032940 secretion by cell; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0006952 defense response; GO:0043299 leukocyte degranulation; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0021543 pallium development; GO:0010595 positive regulation of endothelial cell migration; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0045766 positive regulation of angiogenesis; GO:0033993 response to lipid; GO:0031960 response to corticosteroid; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0006355 regulation of transcription, DNA-templated; GO:0042742 defense response to bacterium; GO:1901342 regulation of vasculature development; GO:0010634 positive regulation of epithelial cell migration; GO:0010556 regulation of macromolecule biosynthetic process; GO:0043312 neutrophil degranulation; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0031099 regeneration; GO:0040012 regulation of locomotion; GO:0009725 response to hormone; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0030425 dendrite; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0043025 neuronal cell body; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0044464 cell part; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0030670 phagocytic vesicle membrane; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0030141 secretory granule; GO:0030139 endocytic vesicle; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0098588 bounding membrane of organelle; GO:0030666 endocytic vesicle membrane; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0045335 phagocytic vesicle; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0030424 axon; GO:0036477 somatodendritic compartment; GO:0042581 specific granule; GO:0044297 cell body; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0019834 phospholipase A2 inhibitor activity; GO:0005544 calcium-dependent phospholipid binding; GO:0055102 lipase inhibitor activity; GO:0043167 ion binding; GO:0004859 phospholipase inhibitor activity; GO:0005515 protein binding; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0048306 calcium-dependent protein binding; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0005543 phospholipid binding; GO:0008289 lipid binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0005509 calcium ion binding; ","K17089"]
["P12532","Creatine kinase U-type, mitochondrial OS=Homo sapiens OX=9606 GN=CKMT1A","CKMT1A",47.036,134.53,29.7,9,17,7,0.941,0.914,0.987,1.056,1.023,1.043,1.099,0.0176,"mitochondria\r","GO:0016310 phosphorylation; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:0044699 single-organism process; GO:0006600 creatine metabolic process; GO:1901605 alpha-amino acid metabolic process; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0006575 cellular modified amino acid metabolic process; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0006082 organic acid metabolic process; GO:0009987 cellular process; GO:0043436 oxoacid metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0044429 mitochondrial part; GO:0031090 organelle membrane; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0005740 mitochondrial envelope; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:0031975 envelope; GO:0019866 organelle inner membrane; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0031966 mitochondrial membrane; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0004111 creatine kinase activity; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016775 phosphotransferase activity, nitrogenous group as acceptor; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016301 kinase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0016740 transferase activity; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K00933","E2.7.3.2; creatine kinase [EC:2.7.3.2]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00330 Arginine and proline metabolism - Homo sapiens (human); ","IPR022413; IPR014746; IPR022414; ","\"ATP:guanido phosphotransferase, N-terminal; Glutamine synthetase/guanido kinase, catalytic domain; ATP:guanido phosphotransferase, catalytic domain; \"\r"]
["P12694","2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=BCKDHA","BCKDHA",50.47,11.11,11,5,5,5,1.093,1.104,1.003,0.776,1.005,1.01,0.872,0.195,"mitochondria\r","GO:0055114 oxidation-reduction process; GO:0044712 single-organism catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006081 cellular aldehyde metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044699 single-organism process; GO:0044282 small molecule catabolic process; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0046395 carboxylic acid catabolic process; GO:1901575 organic substance catabolic process; GO:0009083 branched-chain amino acid catabolic process; GO:0008152 metabolic process; GO:1901565 organonitrogen compound catabolic process; GO:0006520 cellular amino acid metabolic process; GO:0044710 single-organism metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0016054 organic acid catabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0044248 cellular catabolic process; GO:0009063 cellular amino acid catabolic process; GO:0006082 organic acid metabolic process; GO:0009081 branched-chain amino acid metabolic process; GO:0046487 glyoxylate metabolic process; GO:0009987 cellular process; GO:0009056 catabolic process; GO:0043436 oxoacid metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0045240 dihydrolipoyl dehydrogenase complex; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:1990204 oxidoreductase complex; GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0045239 tricarboxylic acid cycle enzyme complex; GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0003824 catalytic activity; GO:0005488 binding; GO:0016830 carbon-carbon lyase activity; GO:0043167 ion binding; GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors; GO:0016831 carboxy-lyase activity; GO:0003863 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0016829 lyase activity; GO:0005515 protein binding; GO:0003826 alpha-ketoacid dehydrogenase activity; GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor; GO:0016491 oxidoreductase activity; ","K00166","BCKDHA; 2-oxoisovalerate dehydrogenase E1 component alpha subunit [EC:1.2.4.4]","hsa00280 Valine, leucine and isoleucine degradation - Homo sapiens (human); hsa00640 Propanoate metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR001017; IPR029061; ","\"Dehydrogenase, E1 component; Thiamin diphosphate-binding fold; \"\r"]
["P12814","Alpha-actinin-1 OS=Homo sapiens OX=9606 GN=ACTN1","ACTN1",103.06,321.27,56.2,47,131,29,1.094,1.082,1.119,0.94,0.904,0.906,0.835,0.000358,"cyto_nucl\r","GO:0044085 cellular component biogenesis; GO:0010941 regulation of cell death; GO:0048869 cellular developmental process; GO:0045216 cell-cell junction organization; GO:0032989 cellular component morphogenesis; GO:0044699 single-organism process; GO:0051234 establishment of localization; GO:2001141 regulation of RNA biosynthetic process; GO:0022610 biological adhesion; GO:0030036 actin cytoskeleton organization; GO:0022607 cellular component assembly; GO:0032879 regulation of localization; GO:0007160 cell-matrix adhesion; GO:0034332 adherens junction organization; GO:0007155 cell adhesion; GO:0007045 cell-substrate adherens junction assembly; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0032502 developmental process; GO:0007044 cell-substrate junction assembly; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0002520 immune system development; GO:0030220 platelet formation; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0048041 focal adhesion assembly; GO:0000902 cell morphogenesis; GO:0006810 transport; GO:1903506 regulation of nucleic acid-templated transcription; GO:1902589 single-organism organelle organization; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0032940 secretion by cell; GO:0019222 regulation of metabolic process; GO:0034333 adherens junction assembly; GO:0048856 anatomical structure development; GO:0097435 supramolecular fiber organization; GO:0051271 negative regulation of cellular component movement; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0034329 cell junction assembly; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0043067 regulation of programmed cell death; GO:0007015 actin filament organization; GO:0002576 platelet degranulation; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0051017 actin filament bundle assembly; GO:0048468 cell development; GO:0000904 cell morphogenesis involved in differentiation; GO:0009653 anatomical structure morphogenesis; GO:0030154 cell differentiation; GO:1902578 single-organism localization; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0051764 actin crosslink formation; GO:0030099 myeloid cell differentiation; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0036344 platelet morphogenesis; GO:0016192 vesicle-mediated transport; GO:0010556 regulation of macromolecule biosynthetic process; GO:0002376 immune system process; GO:0051252 regulation of RNA metabolic process; GO:0030097 hemopoiesis; GO:0048534 hematopoietic or lymphoid organ development; GO:0061572 actin filament bundle organization; GO:0051639 actin filament network formation; GO:0045055 regulated exocytosis; GO:0034330 cell junction organization; GO:0031589 cell-substrate adhesion; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0030029 actin filament-based process; GO:0051179 localization; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; GO:0006887 exocytosis; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0098862 cluster of actin-based cell projections; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0005913 cell-cell adherens junction; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0031674 I band; GO:0014704 intercalated disc; GO:0031143 pseudopodium; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0042641 actomyosin; GO:0043233 organelle lumen; GO:0005924 cell-substrate adherens junction; GO:0031252 cell leading edge; GO:0042995 cell projection; GO:0044430 cytoskeletal part; GO:0070161 anchoring junction; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0099081 supramolecular polymer; GO:0044449 contractile fiber part; GO:0043230 extracellular organelle; GO:0034774 secretory granule lumen; GO:0005615 extracellular space; GO:0005903 brush border; GO:0031410 cytoplasmic vesicle; GO:0030054 cell junction; GO:0044291 cell-cell contact zone; GO:0071944 cell periphery; GO:0030016 myofibril; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0099512 supramolecular fiber; GO:0030018 Z disc; GO:0005911 cell-cell junction; GO:0032432 actin filament bundle; GO:0005856 cytoskeleton; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0043292 contractile fiber; GO:1903561 extracellular vesicle; GO:0005912 adherens junction; GO:0005916 fascia adherens; GO:0030141 secretory granule; GO:0001725 stress fiber; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0097517 contractile actin filament bundle; GO:0005829 cytosol; GO:0015629 actin cytoskeleton; GO:0043226 organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0030017 sarcomere; GO:0031093 platelet alpha granule lumen; GO:0001726 ruffle; GO:0031091 platelet alpha granule; GO:0044444 cytoplasmic part; ","GO:0051015 actin filament binding; GO:0003723 RNA binding; GO:0005102 receptor binding; GO:0003725 double-stranded RNA binding; GO:0043167 ion binding; GO:0046983 protein dimerization activity; GO:0044877 macromolecular complex binding; GO:0005178 integrin binding; GO:0005515 protein binding; GO:0003712 transcription cofactor activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0050839 cell adhesion molecule binding; GO:0042802 identical protein binding; GO:0008092 cytoskeletal protein binding; GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity; GO:0042803 protein homodimerization activity; GO:0017166 vinculin binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0003779 actin binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0044325 ion channel binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0003713 transcription coactivator activity; GO:0005509 calcium ion binding; GO:0000988 transcription factor activity, protein binding; GO:0032403 protein complex binding; ","K05699","ACTN1_4; actinin alpha 1/4","hsa05322 Systemic lupus erythematosus - Homo sapiens (human); hsa04530 Tight junction - Homo sapiens (human); hsa05146 Amoebiasis - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa05203 Viral carcinogenesis - Homo sapiens (human); hsa04670 Leukocyte transendothelial migration - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa04520 Adherens junction - Homo sapiens (human); ","IPR014837; IPR002048; IPR011992; IPR001715; ","\"EF-hand, Ca insensitive; EF-hand domain; EF-hand domain pair; Calponin homology domain; \"\r"]
["P12830","Cadherin-1 OS=Homo sapiens OX=9606 GN=CDH1","CDH1",97.455,86.426,13.5,9,13,8,0.984,0.888,0.944,1.061,1.058,1.069,1.132,0.053,"peroxisome\r","GO:0044085 cellular component biogenesis; GO:0044409 entry into host; GO:0048732 gland development; GO:1903533 regulation of protein targeting; GO:0007420 brain development; GO:0009891 positive regulation of biosynthetic process; GO:0090002 establishment of protein localization to plasma membrane; GO:0022610 biological adhesion; GO:0032879 regulation of localization; GO:0034332 adherens junction organization; GO:0009719 response to endogenous stimulus; GO:0071681 cellular response to indole-3-methanol; GO:0007155 cell adhesion; GO:0044419 interspecies interaction between organisms; GO:0008104 protein localization; GO:0007399 nervous system development; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0072657 protein localization to membrane; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0097306 cellular response to alcohol; GO:0007009 plasma membrane organization; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0010243 response to organonitrogen compound; GO:0048513 animal organ development; GO:0007417 central nervous system development; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:1901698 response to nitrogen compound; GO:0098602 single organism cell adhesion; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051223 regulation of protein transport; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0042307 positive regulation of protein import into nucleus; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0007162 negative regulation of cell adhesion; GO:0051806 entry into cell of other organism involved in symbiotic interaction; GO:1901700 response to oxygen-containing compound; GO:0022408 negative regulation of cell-cell adhesion; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0021983 pituitary gland development; GO:1990778 protein localization to cell periphery; GO:0060341 regulation of cellular localization; GO:0042990 regulation of transcription factor import into nucleus; GO:0042493 response to drug; GO:1902578 single-organism localization; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0043062 extracellular structure organization; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:1902580 single-organism cellular localization; GO:0030900 forebrain development; GO:0032880 regulation of protein localization; GO:0007275 multicellular organism development; GO:0034613 cellular protein localization; GO:0090150 establishment of protein localization to membrane; GO:0051254 positive regulation of RNA metabolic process; GO:0048731 system development; GO:0007416 synapse assembly; GO:0071407 cellular response to organic cyclic compound; GO:0097305 response to alcohol; GO:0010033 response to organic substance; GO:0050808 synapse organization; GO:0030155 regulation of cell adhesion; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0045184 establishment of protein localization; GO:0030182 neuron differentiation; GO:1900182 positive regulation of protein localization to nucleus; GO:0072659 protein localization to plasma membrane; GO:0046822 regulation of nucleocytoplasmic transport; GO:1904951 positive regulation of establishment of protein localization; GO:0031325 positive regulation of cellular metabolic process; GO:0061024 membrane organization; GO:0031328 positive regulation of cellular biosynthetic process; GO:0071248 cellular response to metal ion; GO:0051179 localization; GO:1903827 regulation of cellular protein localization; GO:1904591 positive regulation of protein import; GO:0010256 endomembrane system organization; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0045216 cell-cell junction organization; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0051234 establishment of localization; GO:2001141 regulation of RNA biosynthetic process; GO:0016337 single organismal cell-cell adhesion; GO:0042306 regulation of protein import into nucleus; GO:0022607 cellular component assembly; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0022617 extracellular matrix disassembly; GO:0046824 positive regulation of nucleocytoplasmic transport; GO:0060322 head development; GO:0030198 extracellular matrix organization; GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules; GO:0010035 response to inorganic substance; GO:0033036 macromolecule localization; GO:0070887 cellular response to chemical stimulus; GO:0071285 cellular response to lithium ion; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0010226 response to lithium ion; GO:0031326 regulation of cellular biosynthetic process; GO:0009636 response to toxic substance; GO:0098609 cell-cell adhesion; GO:0048522 positive regulation of cellular process; GO:0032386 regulation of intracellular transport; GO:0010038 response to metal ion; GO:0051050 positive regulation of transport; GO:0071417 cellular response to organonitrogen compound; GO:0030260 entry into host cell; GO:0071680 response to indole-3-methanol; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0030030 cell projection organization; GO:1901699 cellular response to nitrogen compound; GO:0021536 diencephalon development; GO:0035270 endocrine system development; GO:0051828 entry into other organism involved in symbiotic interaction; GO:1900180 regulation of protein localization to nucleus; GO:0019222 regulation of metabolic process; GO:0071241 cellular response to inorganic substance; GO:0048856 anatomical structure development; GO:0051222 positive regulation of protein transport; GO:0016043 cellular component organization; GO:0090316 positive regulation of intracellular protein transport; GO:1903829 positive regulation of cellular protein localization; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0071310 cellular response to organic substance; GO:1904589 regulation of protein import; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0070201 regulation of establishment of protein localization; GO:0030154 cell differentiation; GO:0035635 entry of bacterium into host cell; GO:0009987 cellular process; GO:0033157 regulation of intracellular protein transport; GO:0042993 positive regulation of transcription factor import into nucleus; GO:0006355 regulation of transcription, DNA-templated; GO:0032388 positive regulation of intracellular transport; GO:0051049 regulation of transport; GO:0044802 single-organism membrane organization; GO:0010556 regulation of macromolecule biosynthetic process; GO:0031175 neuron projection development; GO:0051701 interaction with host; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0022407 regulation of cell-cell adhesion; GO:0051641 cellular localization; GO:0070727 cellular macromolecule localization; GO:1901701 cellular response to oxygen-containing compound; GO:0034330 cell junction organization; GO:0044767 single-organism developmental process; GO:0071495 cellular response to endogenous stimulus; GO:0022411 cellular component disassembly; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0019898 extrinsic component of membrane; GO:0098857 membrane microdomain; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0005913 cell-cell adherens junction; GO:0005623 cell; GO:0009898 cytoplasmic side of plasma membrane; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0098590 plasma membrane region; GO:0005622 intracellular; GO:0098791 Golgi subcompartment; GO:0098589 membrane region; GO:0030027 lamellipodium; GO:0043227 membrane-bounded organelle; GO:0016600 flotillin complex; GO:0098552 side of membrane; GO:0031252 cell leading edge; GO:0042995 cell projection; GO:0098797 plasma membrane protein complex; GO:0019897 extrinsic component of plasma membrane; GO:0070161 anchoring junction; GO:0005901 caveola; GO:0005576 extracellular region; GO:0016328 lateral plasma membrane; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0016342 catenin complex; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0031410 cytoplasmic vesicle; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005911 cell-cell junction; GO:0098562 cytoplasmic side of membrane; GO:0005856 cytoskeleton; GO:0044425 membrane part; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0044431 Golgi apparatus part; GO:0005768 endosome; GO:0045121 membrane raft; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0015629 actin cytoskeleton; GO:0016021 integral component of membrane; GO:0043296 apical junction complex; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0044853 plasma membrane raft; GO:0005802 trans-Golgi network; GO:0005794 Golgi apparatus; GO:0031984 organelle subcompartment; GO:0044444 cytoplasmic part; ","GO:0045295 gamma-catenin binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0030506 ankyrin binding; GO:0032794 GTPase activating protein binding; GO:0050839 cell adhesion molecule binding; GO:0097367 carbohydrate derivative binding; GO:0008092 cytoskeletal protein binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005509 calcium ion binding; GO:0001948 glycoprotein binding; GO:0008013 beta-catenin binding; ","K05689","CDH1; cadherin 1, type 1, E-cadherin","hsa05216 Thyroid cancer - Homo sapiens (human); hsa05100 Bacterial invasion of epithelial cells - Homo sapiens (human); hsa04015 Rap1 signaling pathway - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa05219 Bladder cancer - Homo sapiens (human); hsa04371 Apelin signaling pathway - Homo sapiens (human); hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human); hsa05213 Endometrial cancer - Homo sapiens (human); hsa04390 Hippo signaling pathway - Homo sapiens (human); hsa04520 Adherens junction - Homo sapiens (human); hsa05226 Gastric cancer - Homo sapiens (human); hsa04514 Cell adhesion molecules (CAMs) - Homo sapiens (human); hsa05218 Melanoma - Homo sapiens (human); ","IPR015919; IPR027397; IPR014868; IPR000233; IPR002126; ","\"Cadherin-like; Catenin binding domain; Cadherin prodomain; Cadherin, cytoplasmic domain; Cadherin; \"\r"]
["P12883","Myosin-7 OS=Homo sapiens OX=9606 GN=MYH7","MYH7",223.09,8.1237,15.9,26,45,1,0.74,0.783,1.127,1.169,1.083,1.085,1.259,0.138,"cytoplasm\r","GO:0030048 actin filament-based movement; GO:0065008 regulation of biological quality; GO:0070252 actin-mediated cell contraction; GO:0003012 muscle system process; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0060415 muscle tissue morphogenesis; GO:0009117 nucleotide metabolic process; GO:0014887 cardiac muscle adaptation; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0048729 tissue morphogenesis; GO:0008152 metabolic process; GO:0007507 heart development; GO:0043500 muscle adaptation; GO:0006753 nucleoside phosphate metabolic process; GO:0003208 cardiac ventricle morphogenesis; GO:0014819 regulation of skeletal muscle contraction; GO:0044057 regulation of system process; GO:0019693 ribose phosphate metabolic process; GO:0032502 developmental process; GO:0014862 regulation of skeletal muscle contraction by chemo-mechanical energy conversion; GO:0009888 tissue development; GO:0014898 cardiac muscle hypertrophy in response to stress; GO:0060537 muscle tissue development; GO:0055008 cardiac muscle tissue morphogenesis; GO:0003007 heart morphogenesis; GO:0044281 small molecule metabolic process; GO:0050879 multicellular organismal movement; GO:0044763 single-organism cellular process; GO:0006941 striated muscle contraction; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0090257 regulation of muscle system process; GO:0031449 regulation of slow-twitch skeletal muscle fiber contraction; GO:0032501 multicellular organismal process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0006942 regulation of striated muscle contraction; GO:0048513 animal organ development; GO:0003229 ventricular cardiac muscle tissue development; GO:0050789 regulation of biological process; GO:0014896 muscle hypertrophy; GO:0007517 muscle organ development; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:0048644 muscle organ morphogenesis; GO:0009887 animal organ morphogenesis; GO:0003015 heart process; GO:0014888 striated muscle adaptation; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0003013 circulatory system process; GO:0048856 anatomical structure development; GO:0014897 striated muscle hypertrophy; GO:0014706 striated muscle tissue development; GO:0072359 circulatory system development; GO:0044707 single-multicellular organism process; GO:0014733 regulation of skeletal muscle adaptation; GO:0030049 muscle filament sliding; GO:0048738 cardiac muscle tissue development; GO:0007512 adult heart development; GO:0006725 cellular aromatic compound metabolic process; GO:0003299 muscle hypertrophy in response to stress; GO:0009259 ribonucleotide metabolic process; GO:1903522 regulation of blood circulation; GO:0008016 regulation of heart contraction; GO:0060048 cardiac muscle contraction; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:0014724 regulation of twitch skeletal muscle contraction; GO:0014728 regulation of the force of skeletal muscle contraction; GO:0071704 organic substance metabolic process; GO:0009653 anatomical structure morphogenesis; GO:0006936 muscle contraction; GO:0046483 heterocycle metabolic process; GO:0055010 ventricular cardiac muscle tissue morphogenesis; GO:0006139 nucleobase-containing compound metabolic process; GO:0003300 cardiac muscle hypertrophy; GO:0050881 musculoskeletal movement; GO:0008015 blood circulation; GO:0061061 muscle structure development; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0060047 heart contraction; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0003231 cardiac ventricle development; GO:0009119 ribonucleoside metabolic process; GO:0009987 cellular process; GO:0046034 ATP metabolic process; GO:0003008 system process; GO:0006950 response to stress; GO:0033275 actin-myosin filament sliding; GO:0048731 system development; GO:0006937 regulation of muscle contraction; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0003206 cardiac chamber morphogenesis; GO:0044238 primary metabolic process; GO:0003009 skeletal muscle contraction; GO:0006163 purine nucleotide metabolic process; GO:0003205 cardiac chamber development; GO:0046128 purine ribonucleoside metabolic process; GO:0043502 regulation of muscle adaptation; GO:0014883 transition between fast and slow fiber; GO:0006793 phosphorus metabolic process; GO:0044767 single-organism developmental process; GO:0002027 regulation of heart rate; GO:0030029 actin filament-based process; GO:0002026 regulation of the force of heart contraction; GO:0019637 organophosphate metabolic process; GO:0006928 movement of cell or subcellular component; GO:0009150 purine ribonucleotide metabolic process; GO:0065007 biological regulation; GO:1901564 organonitrogen compound metabolic process; GO:0009123 nucleoside monophosphate metabolic process; ","GO:0030016 myofibril; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0030018 Z disc; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0031674 I band; GO:0032432 actin filament bundle; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0044464 cell part; GO:0005622 intracellular; GO:0016460 myosin II complex; GO:0043292 contractile fiber; GO:0001725 stress fiber; GO:0016459 myosin complex; GO:0032982 myosin filament; GO:0042641 actomyosin; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0005859 muscle myosin complex; GO:0097517 contractile actin filament bundle; GO:0015629 actin cytoskeleton; GO:0099081 supramolecular polymer; GO:0043226 organelle; GO:0030017 sarcomere; GO:0044449 contractile fiber part; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0003774 motor activity; GO:1901265 nucleoside phosphate binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0016887 ATPase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0008092 cytoskeletal protein binding; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0000146 microfilament motor activity; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0030898 actin-dependent ATPase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0005516 calmodulin binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0042623 ATPase activity, coupled; GO:0003779 actin binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; ","K17751","MYH6_7; myosin heavy chain 6/7","hsa04260 Cardiac muscle contraction - Homo sapiens (human); hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human); hsa05414 Dilated cardiomyopathy (DCM) - Homo sapiens (human); hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human); hsa05416 Viral myocarditis - Homo sapiens (human); hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human); hsa05410 Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human); ","IPR002928; IPR004009; IPR027417; IPR001609; IPR027401; ","\"Myosin tail; Myosin, N-terminal, SH3-like; P-loop containing nucleoside triphosphate hydrolase; Myosin head, motor domain; Myosin-like IQ motif-containing domain; \"\r"]
["P12931","Proto-oncogene tyrosine-protein kinase Src OS=Homo sapiens OX=9606 GN=SRC","SRC",59.834,13.668,7.3,4,5,3,0.91,0.959,1.047,0.942,1.179,0.961,1.057,0.564,"cytoplasm\r",{"$cut":{"chars":31840,"head":"GO:0044700 single organism signaling; GO:0002694 regulation of leukocyte activation; GO:0048008 platelet-derived growth factor receptor signaling pathway; GO:0048732 gland development; GO:2001286 regulation of caveolin-mediated endocytosis; GO:0022414 reproductive process; GO:0036119 response to platelet-derived growth factor; GO:0018212 peptidyl-tyrosine modification; GO:0030038 contractile actin filament bundle assembly; GO:0070555 response to interleukin-1; GO:0044237 cellular metabolic process; GO:0009607 response to biotic stimulus; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0050847 progesterone receptor signaling pathway; GO:0051974 negative regulation of telomerase activity; GO:0034332 adherens junction organization; GO:0031333 negative regulation of protein complex assembly; GO:0052548 regulation of endopeptidase activity; GO:0086103 G-protein coupled receptor signaling pathway involved in heart process; GO:0051054 positive regulation of DNA metabolic process; GO:0030168 platelet activation; GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity; GO:0080090 regulation of primary metabolic process; GO:0060828 regulation of canonical Wnt signaling pathway; GO:0048870 cell motility; GO:0071559 response to transforming growth factor beta; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0006810 transport; GO:1902532 negative regulation of intracellular signal transduction; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0048010 vascular endothelial growth factor receptor signaling pathway; GO:0060548 negative regulation of cell death; GO:2000392 regulation of lamellipodium morphogenesis; GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0002009 morphogenesis of an epithelium; GO:0044707 single-multicellular organism process; GO:0016310 phosphorylation; GO:0030316 osteoclast differentiation; GO:0051806 entry into cell of other organism involved in symbiotic interaction; GO:0032211 negative regulation of telomere maintenance via telomerase; GO:0045892 negative regulation of transcription, DNA-templated; GO:0009653 anatomical structure morphogenesis; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0071229 cellular response to acid chemical; GO:0009889 regulation of biosynthetic process; GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:2000641 regulation of early endosome to late endosome transport; GO:1902680 positive regulation of RNA biosynthetic process; GO:0061458 reproductive system development; GO:0038093 Fc receptor signaling pathway; GO:0060562 epithelial tube morphogenesis; GO:0032496 response to lipopolysaccharide; GO:0051057 positive regulation of small GTPase mediated signal transduction; GO:0032462 regulation of protein homooligomerization; GO:0008283 cell proliferation; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:2000278 regulation of DNA biosynthetic process; GO:0014911 positive regulation of smooth muscle cell migration; GO:1900182 positive regulation of protein localization to nucleus; GO:2001251 negative regulation of chromosome organization; GO:0070613 regulation of protein processing; GO:0071219 cellular response to molecule of bacterial origin; GO:0010447 response to acidic pH; GO:0006955 immune response; GO:1903727 positive regulation of phospholipid metabolic process; GO:0043412 macromolecule modification; GO:0071393 cellular response to progesterone stimulus; GO:0018209 peptidyl-serine modification; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0045216 cell-cell junction organization; GO:0051046 regulation of secretion; GO:0051253 negative regulation of RNA metabolic process; GO:0071383 cellular resp"}},"GO:0016020 membrane; GO:0044421 extracellular region part; GO:0019898 extrinsic component of membrane; GO:0031090 organelle membrane; GO:0098857 membrane microdomain; GO:0032587 ruffle membrane; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0009898 cytoplasmic side of plasma membrane; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0098590 plasma membrane region; GO:0031256 leading edge membrane; GO:0005622 intracellular; GO:0005764 lysosome; GO:0098589 membrane region; GO:0014069 postsynaptic density; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0097458 neuron part; GO:0000323 lytic vacuole; GO:0098552 side of membrane; GO:0031252 cell leading edge; GO:0099513 polymeric cytoskeletal fiber; GO:0042995 cell projection; GO:0005770 late endosome; GO:0044430 cytoskeletal part; GO:0031967 organelle envelope; GO:0019897 extrinsic component of plasma membrane; GO:0005901 caveola; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0099081 supramolecular polymer; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0098794 postsynapse; GO:0031975 envelope; GO:0005773 vacuole; GO:0043234 protein complex; GO:0099572 postsynaptic specialization; GO:0031966 mitochondrial membrane; GO:0043230 extracellular organelle; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0031234 extrinsic component of cytoplasmic side of plasma membrane; GO:0098562 cytoplasmic side of membrane; GO:0032279 asymmetric synapse; GO:0005740 mitochondrial envelope; GO:0005856 cytoskeleton; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0019866 organelle inner membrane; GO:0048471 perinuclear region of cytoplasm; GO:0005884 actin filament; GO:0005768 endosome; GO:0045121 membrane raft; GO:0098984 neuron to neuron synapse; GO:0044456 synapse part; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0002102 podosome; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0015629 actin cytoskeleton; GO:0045202 synapse; GO:0043226 organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0044853 plasma membrane raft; GO:0031253 cell projection membrane; GO:0001726 ruffle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0031625 ubiquitin protein ligase binding; GO:0005102 receptor binding; GO:0019901 protein kinase binding; GO:0097110 scaffold protein binding; GO:0004713 protein tyrosine kinase activity; GO:0046875 ephrin receptor binding; GO:0005178 integrin binding; GO:0005515 protein binding; GO:0051427 hormone receptor binding; GO:0004672 protein kinase activity; GO:0005158 insulin receptor binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0020037 heme binding; GO:0016301 kinase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0045296 cadherin binding; GO:0032550 purine ribonucleoside binding; GO:0035258 steroid hormone receptor binding; GO:0008022 protein C-terminus binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0046906 tetrapyrrole binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0030331 estrogen receptor binding; GO:0005524 ATP binding; GO:0030674 protein binding, bridging; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0070851 growth factor receptor binding; GO:0000166 nucleotide binding; GO:0019900 kinase binding; GO:0051219 phosphoprotein binding; GO:0005070 SH3/SH2 adaptor activity; GO:0050839 cell adhesion molecule binding; GO:0032549 ribonucleoside binding; GO:0004715 non-membrane spanning protein tyrosine kinase activity; GO:0097367 carbohydrate derivative binding; GO:0035591 signaling adaptor activity; GO:0042169 SH2 domain binding; GO:0035257 nuclear hormone receptor binding; GO:0005080 protein kinase C binding; GO:0044325 ion channel binding; GO:0019904 protein domain specific binding; GO:0060090 binding, bridging; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0019899 enzyme binding; GO:0032403 protein complex binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0036094 small molecule binding; ","K05704","SRC; tyrosine-protein kinase Src [EC:2.7.10.2]","hsa05120 Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human); hsa04921 Oxytocin signaling pathway - Homo sapiens (human); hsa05100 Bacterial invasion of epithelial cells - Homo sapiens (human); hsa05152 Tuberculosis - Homo sapiens (human); hsa04015 Rap1 signaling pathway - Homo sapiens (human); hsa04625 C-type lectin receptor signaling pathway - Homo sapiens (human); hsa04530 Tight junction - Homo sapiens (human); hsa04370 VEGF signaling pathway - Homo sapiens (human); hsa04137 Mitophagy - animal - Homo sapiens (human); hsa05167 Kaposi's sarcoma-associated herpesvirus infection - Homo sapiens (human); hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human); hsa04144 Endocytosis - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa04750 Inflammatory mediator regulation of TRP channels - Homo sapiens (human); hsa05131 Shigellosis - Homo sapiens (human); hsa04062 Chemokine signaling pathway - Homo sapiens (human); hsa05219 Bladder cancer - Homo sapiens (human); hsa04540 Gap junction - Homo sapiens (human); hsa04912 GnRH signaling pathway - Homo sapiens (human); hsa04727 GABAergic synapse - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa05203 Viral carcinogenesis - Homo sapiens (human); hsa04611 Platelet activation - Homo sapiens (human); hsa04917 Prolactin signaling pathway - Homo sapiens (human); hsa04520 Adherens junction - Homo sapiens (human); hsa01522 Endocrine resistance - Homo sapiens (human); hsa04012 ErbB signaling pathway - Homo sapiens (human); hsa05161 Hepatitis B - Homo sapiens (human); hsa04360 Axon guidance - Homo sapiens (human); hsa01521 EGFR tyrosine kinase inhibitor resistance - Homo sapiens (human); hsa04926 Relaxin signaling pathway - Homo sapiens (human); hsa04915 Estrogen signaling pathway - Homo sapiens (human); ","IPR001452; IPR000980; IPR000719; IPR020635; IPR001245; IPR011009; ","\"SH3 domain; SH2 domain; Protein kinase domain; Tyrosine-protein kinase, catalytic domain; Serine-threonine/tyrosine-protein kinase catalytic domain; Protein kinase-like domain; \"\r"]
["P12955","Xaa-Pro dipeptidase OS=Homo sapiens OX=9606 GN=PEPD","PEPD",54.548,45.522,22.7,11,12,11,0.929,0.983,0.988,0.906,1.05,1.065,1.042,0.523,"cyto_nucl\r","GO:0044707 single-multicellular organism process; GO:0044712 single-organism catabolic process; GO:0044281 small molecule metabolic process; GO:0044236 multicellular organism metabolic process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:0044699 single-organism process; GO:0044238 primary metabolic process; GO:0032501 multicellular organismal process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0044243 multicellular organismal catabolic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0044710 single-organism metabolic process; GO:0032963 collagen metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0006508 proteolysis; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006082 organic acid metabolic process; GO:0044259 multicellular organismal macromolecule metabolic process; GO:0009056 catabolic process; GO:0009987 cellular process; GO:0043436 oxoacid metabolic process; GO:0030574 collagen catabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:0004180 carboxypeptidase activity; GO:0102009 proline dipeptidase activity; GO:0008233 peptidase activity; GO:0008238 exopeptidase activity; GO:0043167 ion binding; GO:0008235 metalloexopeptidase activity; GO:0005515 protein binding; GO:0004177 aminopeptidase activity; GO:0008237 metallopeptidase activity; GO:0016787 hydrolase activity; GO:0030145 manganese ion binding; GO:0046914 transition metal ion binding; GO:0004181 metallocarboxypeptidase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0016805 dipeptidase activity; ","K14213",null,null,"IPR007865; IPR029149; IPR000994; IPR028980; ","\"Aminopeptidase P, N-terminal; Creatinase/Aminopeptidase P/Spt16, N-terminal; Peptidase M24; Creatinase/Aminopeptidase P, N-terminal; \"\r"]
["P12956","X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6","XRCC6",69.842,216.3,43.2,29,68,29,0.942,0.956,0.963,1.035,1.031,1.035,1.084,0.00026,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0032481 positive regulation of type I interferon production; GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0006266 DNA ligation; GO:0019043 establishment of viral latency; GO:0097659 nucleic acid-templated transcription; GO:0007420 brain development; GO:0009891 positive regulation of biosynthetic process; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0065003 macromolecular complex assembly; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0002443 leukocyte mediated immunity; GO:0071214 cellular response to abiotic stimulus; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044763 single-organism cellular process; GO:0032774 RNA biosynthetic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0051291 protein heterooligomerization; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0071480 cellular response to gamma radiation; GO:0007417 central nervous system development; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0071470 cellular response to osmotic stress; GO:0010604 positive regulation of macromolecule metabolic process; GO:0032200 telomere organization; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0097680 double-strand break repair via classical nonhomologous end joining; GO:0071481 cellular response to X-ray; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0044707 single-multicellular organism process; GO:0002283 neutrophil activation involved in immune response; GO:0042127 regulation of cell proliferation; GO:0006259 DNA metabolic process; GO:0009628 response to abiotic stimulus; GO:0001819 positive regulation of cytokine production; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0060249 anatomical structure homeostasis; GO:0051239 regulation of multicellular organismal process; GO:0051259 protein oligomerization; GO:0045892 negative regulation of transcription, DNA-templated; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0007275 multicellular organism development; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0006461 protein complex assembly; GO:0051254 positive regulation of RNA metabolic process; GO:0006950 response to stress; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0002263 cell activation involved in immune response; GO:0009892 negative regulation of metabolic process; GO:0006974 cellular response to DNA damage stimulus; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0045055 regulated exocytosis; GO:0009890 negative regulation of biosynthetic process; GO:0010165 response to X-ray; GO:0071474 cellular hyperosmotic response; GO:0051276 chromosome organization; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0001775 cell activation; GO:0051179 localization; GO:0006955 immune response; GO:0031328 positive regulation of cellular biosynthetic process; GO:0000723 telomere maintenance; GO:0006887 exocytosis; GO:0032392 DNA geometric change; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0051253 negative regulation of RNA metabolic process; GO:0051234 establishment of localization; GO:2001141 regulation of RNA biosynthetic process; GO:0051262 protein tetramerization; GO:0022607 cellular component assembly; GO:0009893 positive regulation of metabolic process; GO:0051290 protein heterotetramerization; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0009314 response to radiation; GO:0060322 head development; GO:0019042 viral latency; GO:0071479 cellular response to ionizing radiation; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0006310 DNA recombination; GO:0002274 myeloid leukocyte activation; GO:0071103 DNA conformation change; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0075713 establishment of integrated proviral latency; GO:0071822 protein complex subunit organization; GO:0006970 response to osmotic stress; GO:0031326 regulation of cellular biosynthetic process; GO:0002446 neutrophil mediated immunity; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0009651 response to salt stress; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0016070 RNA metabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0032940 secretion by cell; GO:1902679 negative regulation of RNA biosynthetic process; GO:0019222 regulation of metabolic process; GO:0043299 leukocyte degranulation; GO:0070271 protein complex biogenesis; GO:0048856 anatomical structure development; GO:0006303 double-strand break repair via nonhomologous end joining; GO:0016043 cellular component organization; GO:0032479 regulation of type I interferon production; GO:0006725 cellular aromatic compound metabolic process; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0048660 regulation of smooth muscle cell proliferation; GO:0010332 response to gamma radiation; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0006302 double-strand break repair; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0016032 viral process; GO:0034641 cellular nitrogen compound metabolic process; GO:0036230 granulocyte activation; GO:0009059 macromolecule biosynthetic process; GO:0071472 cellular response to salt stress; GO:0071478 cellular response to radiation; GO:0009987 cellular process; GO:0006355 regulation of transcription, DNA-templated; GO:0071475 cellular hyperosmotic salinity response; GO:0010629 negative regulation of gene expression; GO:0032508 DNA duplex unwinding; GO:0000726 non-recombinational repair; GO:0006972 hyperosmotic response; GO:0006807 nitrogen compound metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0006281 DNA repair; GO:0010212 response to ionizing radiation; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0042538 hyperosmotic salinity response; GO:0044767 single-organism developmental process; GO:0001817 regulation of cytokine production; GO:0010467 gene expression; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0034774 secretory granule lumen; GO:0070419 nonhomologous end joining complex; GO:0000784 nuclear chromosome, telomeric region; GO:0000781 chromosome, telomeric region; GO:0031410 cytoplasmic vesicle; GO:0000782 telomere cap complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0043564 Ku70:Ku80 complex; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0044454 nuclear chromosome part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0099503 secretory vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0032993 protein-DNA complex; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:1990391 DNA repair complex; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0005667 transcription factor complex; GO:0005576 extracellular region; GO:0098687 chromosomal region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0000228 nuclear chromosome; GO:0043234 protein complex; GO:0000783 nuclear telomere cap complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0003690 double-stranded DNA binding; GO:0008026 ATP-dependent helicase activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0042162 telomeric DNA binding; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0016835 carbon-oxygen lyase activity; GO:0016887 ATPase activity; GO:0000975 regulatory region DNA binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0004003 ATP-dependent DNA helicase activity; GO:0043168 anion binding; GO:0003684 damaged DNA binding; GO:0008022 protein C-terminus binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0008094 DNA-dependent ATPase activity; GO:0003678 DNA helicase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003677 DNA binding; GO:0003723 RNA binding; GO:0070035 purine NTP-dependent helicase activity; GO:0051575 5'-deoxyribose-5-phosphate lyase activity; GO:0005524 ATP binding; GO:0004386 helicase activity; GO:0044877 macromolecular complex binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016829 lyase activity; GO:0000166 nucleotide binding; GO:0043565 sequence-specific DNA binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0001067 regulatory region nucleic acid binding; GO:0097367 carbohydrate derivative binding; GO:0044212 transcription regulatory region DNA binding; GO:0003676 nucleic acid binding; GO:0042623 ATPase activity, coupled; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; ","K10884","XRCC6; ATP-dependent DNA helicase 2 subunit 1","hsa03450 Non-homologous end-joining - Homo sapiens (human); ","IPR005161; IPR003034; IPR006164; IPR016194; IPR005160; IPR002035; IPR027388; ","\"Ku70/Ku80, N-terminal alpha/beta; SAP domain; Ku70/Ku80 beta-barrel domain; SPOC-like, C-terminal domain; Ku70/Ku80 C-terminal arm; von Willebrand factor, type A; Ku70, bridge and pillars domain; \"\r"]
["P13010","X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5","XRCC5",82.704,153.15,32.1,20,43,20,0.973,0.961,0.945,1.059,1.061,1.026,1.093,0.003,"cytoplasm\r","GO:0032481 positive regulation of type I interferon production; GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0019043 establishment of viral latency; GO:0097659 nucleic acid-templated transcription; GO:0007420 brain development; GO:0032204 regulation of telomere maintenance; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0007399 nervous system development; GO:0002244 hematopoietic progenitor cell differentiation; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0002443 leukocyte mediated immunity; GO:0071214 cellular response to abiotic stimulus; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0071398 cellular response to fatty acid; GO:0044763 single-organism cellular process; GO:0032774 RNA biosynthetic process; GO:0002520 immune system development; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0071396 cellular response to lipid; GO:0051704 multi-organism process; GO:0006810 transport; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0071480 cellular response to gamma radiation; GO:0051053 negative regulation of DNA metabolic process; GO:0007417 central nervous system development; GO:0044260 cellular macromolecule metabolic process; GO:0071470 cellular response to osmotic stress; GO:0032200 telomere organization; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0051094 positive regulation of developmental process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0071481 cellular response to X-ray; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0033554 cellular response to stress; GO:0002283 neutrophil activation involved in immune response; GO:0042127 regulation of cell proliferation; GO:0009628 response to abiotic stimulus; GO:0001819 positive regulation of cytokine production; GO:0006259 DNA metabolic process; GO:1901700 response to oxygen-containing compound; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0032844 regulation of homeostatic process; GO:0060249 anatomical structure homeostasis; GO:0045597 positive regulation of cell differentiation; GO:0051239 regulation of multicellular organismal process; GO:0045892 negative regulation of transcription, DNA-templated; GO:0042493 response to drug; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0071229 cellular response to acid chemical; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0070542 response to fatty acid; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0006950 response to stress; GO:0048731 system development; GO:0051960 regulation of nervous system development; GO:0060284 regulation of cell development; GO:0016192 vesicle-mediated transport; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0002376 immune system process; GO:0008283 cell proliferation; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0002263 cell activation involved in immune response; GO:0009892 negative regulation of metabolic process; GO:0033044 regulation of chromosome organization; GO:0006974 cellular response to DNA damage stimulus; GO:0045055 regulated exocytosis; GO:0009890 negative regulation of biosynthetic process; GO:0010165 response to X-ray; GO:0071474 cellular hyperosmotic response; GO:2001251 negative regulation of chromosome organization; GO:0051276 chromosome organization; GO:0006996 organelle organization; GO:0048863 stem cell differentiation; GO:0001775 cell activation; GO:0050769 positive regulation of neurogenesis; GO:0051179 localization; GO:0006955 immune response; GO:0050793 regulation of developmental process; GO:0000723 telomere maintenance; GO:0006887 exocytosis; GO:0001101 response to acid chemical; GO:0048869 cellular developmental process; GO:0051129 negative regulation of cellular component organization; GO:0032392 DNA geometric change; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0051253 negative regulation of RNA metabolic process; GO:0051234 establishment of localization; GO:2001141 regulation of RNA biosynthetic process; GO:0009314 response to radiation; GO:0060322 head development; GO:0019042 viral latency; GO:0071479 cellular response to ionizing radiation; GO:0010720 positive regulation of cell development; GO:0070887 cellular response to chemical stimulus; GO:0006310 DNA recombination; GO:0002274 myeloid leukocyte activation; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0071103 DNA conformation change; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0075713 establishment of integrated proviral latency; GO:0006970 response to osmotic stress; GO:0031326 regulation of cellular biosynthetic process; GO:1904429 regulation of t-circle formation; GO:0002446 neutrophil mediated immunity; GO:0051962 positive regulation of nervous system development; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0009651 response to salt stress; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0016070 RNA metabolic process; GO:0010639 negative regulation of organelle organization; GO:0060218 hematopoietic stem cell differentiation; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0090304 nucleic acid metabolic process; GO:0051052 regulation of DNA metabolic process; GO:0006351 transcription, DNA-templated; GO:0032940 secretion by cell; GO:1902679 negative regulation of RNA biosynthetic process; GO:0019222 regulation of metabolic process; GO:0043299 leukocyte degranulation; GO:0048856 anatomical structure development; GO:0006303 double-strand break repair via nonhomologous end joining; GO:2000026 regulation of multicellular organismal development; GO:0016043 cellular component organization; GO:0032479 regulation of type I interferon production; GO:0006725 cellular aromatic compound metabolic process; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0048660 regulation of smooth muscle cell proliferation; GO:0010332 response to gamma radiation; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0006302 double-strand break repair; GO:0044087 regulation of cellular component biogenesis; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0033993 response to lipid; GO:0030154 cell differentiation; GO:0016032 viral process; GO:0034641 cellular nitrogen compound metabolic process; GO:0036230 granulocyte activation; GO:1904430 negative regulation of t-circle formation; GO:0009059 macromolecule biosynthetic process; GO:0071472 cellular response to salt stress; GO:0009987 cellular process; GO:0071478 cellular response to radiation; GO:0045595 regulation of cell differentiation; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0071475 cellular hyperosmotic salinity response; GO:0000726 non-recombinational repair; GO:0032508 DNA duplex unwinding; GO:0006972 hyperosmotic response; GO:0006807 nitrogen compound metabolic process; GO:0033043 regulation of organelle organization; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0032845 negative regulation of homeostatic process; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0048534 hematopoietic or lymphoid organ development; GO:0030097 hemopoiesis; GO:0032205 negative regulation of telomere maintenance; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0006281 DNA repair; GO:0010212 response to ionizing radiation; GO:1901701 cellular response to oxygen-containing compound; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0042538 hyperosmotic salinity response; GO:0044767 single-organism developmental process; GO:0001817 regulation of cytokine production; GO:0010467 gene expression; GO:0031327 negative regulation of cellular biosynthetic process; GO:0051128 regulation of cellular component organization; GO:0050767 regulation of neurogenesis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0034774 secretory granule lumen; GO:0070419 nonhomologous end joining complex; GO:0000784 nuclear chromosome, telomeric region; GO:0000781 chromosome, telomeric region; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0000782 telomere cap complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0043564 Ku70:Ku80 complex; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0044454 nuclear chromosome part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0099503 secretory vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0032993 protein-DNA complex; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:1990391 DNA repair complex; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0098687 chromosomal region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0000228 nuclear chromosome; GO:0043234 protein complex; GO:0000783 nuclear telomere cap complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0031625 ubiquitin protein ligase binding; GO:0003690 double-stranded DNA binding; GO:0008026 ATP-dependent helicase activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0042162 telomeric DNA binding; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0016887 ATPase activity; GO:0000975 regulatory region DNA binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0004003 ATP-dependent DNA helicase activity; GO:0043168 anion binding; GO:0003684 damaged DNA binding; GO:0008022 protein C-terminus binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0008094 DNA-dependent ATPase activity; GO:0003678 DNA helicase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003677 DNA binding; GO:0003723 RNA binding; GO:0070035 purine NTP-dependent helicase activity; GO:0005524 ATP binding; GO:0004386 helicase activity; GO:0044877 macromolecular complex binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0000166 nucleotide binding; GO:0043565 sequence-specific DNA binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0001067 regulatory region nucleic acid binding; GO:0097367 carbohydrate derivative binding; GO:0044212 transcription regulatory region DNA binding; GO:0003676 nucleic acid binding; GO:0042623 ATPase activity, coupled; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0019899 enzyme binding; GO:0036094 small molecule binding; ","K10885","XRCC5; ATP-dependent DNA helicase 2 subunit 2","hsa03450 Non-homologous end-joining - Homo sapiens (human); ","IPR005161; IPR006164; IPR016194; IPR005160; IPR014893; IPR002035; ","\"Ku70/Ku80, N-terminal alpha/beta; Ku70/Ku80 beta-barrel domain; SPOC-like, C-terminal domain; Ku70/Ku80 C-terminal arm; Ku, C-terminal; von Willebrand factor, type A; \"\r"]
["P13073","Cytochrome c oxidase subunit 4 isoform 1, mitochondrial OS=Homo sapiens OX=9606 GN=COX4I1","COX4I1",19.576,24.073,43.8,8,16,8,1.056,0.992,1.009,0.939,1.032,0.944,0.954,0.251,"mitochondria\r","GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0006123 mitochondrial electron transport, cytochrome c to oxygen; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0006753 nucleoside phosphate metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0044765 single-organism transport; GO:0098655 cation transmembrane transport; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006119 oxidative phosphorylation; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0006810 transport; GO:0042221 response to chemical; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0022900 electron transport chain; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0098662 inorganic cation transmembrane transport; GO:0016310 phosphorylation; GO:0034220 ion transmembrane transport; GO:0006725 cellular aromatic compound metabolic process; GO:0042773 ATP synthesis coupled electron transport; GO:0009259 ribonucleotide metabolic process; GO:0022904 respiratory electron transport chain; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0009991 response to extracellular stimulus; GO:0046483 heterocycle metabolic process; GO:1902578 single-organism localization; GO:0006139 nucleobase-containing compound metabolic process; GO:0006812 cation transport; GO:1902600 hydrogen ion transmembrane transport; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009119 ribonucleoside metabolic process; GO:0009987 cellular process; GO:0046034 ATP metabolic process; GO:0098660 inorganic ion transmembrane transport; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0007584 response to nutrient; GO:0044238 primary metabolic process; GO:0045333 cellular respiration; GO:0006163 purine nucleotide metabolic process; GO:0006818 hydrogen transport; GO:0015992 proton transport; GO:0046128 purine ribonucleoside metabolic process; GO:0055085 transmembrane transport; GO:0006793 phosphorus metabolic process; GO:0006811 ion transport; GO:0019637 organophosphate metabolic process; GO:0031667 response to nutrient levels; GO:0009150 purine ribonucleotide metabolic process; GO:0051179 localization; GO:0015672 monovalent inorganic cation transport; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0019866 organelle inner membrane; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0098803 respiratory chain complex; GO:0005751 mitochondrial respiratory chain complex IV; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0070069 cytochrome complex; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005746 mitochondrial respiratory chain; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0045277 respiratory chain complex IV; GO:0031975 envelope; GO:0043234 protein complex; GO:0070469 respiratory chain; GO:0043230 extracellular organelle; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0015075 ion transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0015077 monovalent inorganic cation transmembrane transporter activity; GO:0016676 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor; GO:0016675 oxidoreductase activity, acting on a heme group of donors; GO:0015078 hydrogen ion transmembrane transporter activity; GO:0015002 heme-copper terminal oxidase activity; GO:0016491 oxidoreductase activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0009055 electron carrier activity; GO:0004129 cytochrome-c oxidase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0022890 inorganic cation transmembrane transporter activity; GO:0008324 cation transmembrane transporter activity; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; ","K02263","COX4; cytochrome c oxidase subunit 4","hsa04260 Cardiac muscle contraction - Homo sapiens (human); hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); "]
["P13473","Lysosome-associated membrane glycoprotein 2 OS=Homo sapiens OX=9606 GN=LAMP2","LAMP2",44.96,3.4615,3.7,2,3,2,0.883,0.911,0.907,1.089,1.097,1.108,1.22,5.74e-05,"extracellular\r","GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0072594 establishment of protein localization to organelle; GO:0017038 protein import; GO:0051129 negative regulation of cellular component organization; GO:0044699 single-organism process; GO:0006623 protein targeting to vacuole; GO:0006914 autophagy; GO:0032459 regulation of protein oligomerization; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0072666 establishment of protein localization to vacuole; GO:0033365 protein localization to organelle; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0007033 vacuole organization; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0031333 negative regulation of protein complex assembly; GO:0002274 myeloid leukocyte activation; GO:0046903 secretion; GO:0016236 macroautophagy; GO:0044765 single-organism transport; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0061462 protein localization to lysosome; GO:0032460 negative regulation of protein oligomerization; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0019725 cellular homeostasis; GO:0002444 myeloid leukocyte mediated immunity; GO:0072665 protein localization to vacuole; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0043254 regulation of protein complex assembly; GO:0030163 protein catabolic process; GO:0032940 secretion by cell; GO:0046716 muscle cell cellular homeostasis; GO:0044260 cellular macromolecule metabolic process; GO:0007039 protein catabolic process in the vacuole; GO:0043299 leukocyte degranulation; GO:0061684 chaperone-mediated autophagy; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0009267 cellular response to starvation; GO:0044257 cellular protein catabolic process; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0044267 cellular protein metabolic process; GO:0097352 autophagosome maturation; GO:0002576 platelet degranulation; GO:0044087 regulation of cellular component biogenesis; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:0060249 anatomical structure homeostasis; GO:0031669 cellular response to nutrient levels; GO:0061740 protein targeting to lysosome involved in chaperone-mediated autophagy; GO:0071704 organic substance metabolic process; GO:0071211 protein targeting to vacuole involved in autophagy; GO:0042592 homeostatic process; GO:0009991 response to extracellular stimulus; GO:0006622 protein targeting to lysosome; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0006886 intracellular protein transport; GO:0044248 cellular catabolic process; GO:0036230 granulocyte activation; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0007041 lysosomal transport; GO:0044265 cellular macromolecule catabolic process; GO:0006950 response to stress; GO:0016192 vesicle-mediated transport; GO:0032462 regulation of protein homooligomerization; GO:0002376 immune system process; GO:0048284 organelle fusion; GO:0071702 organic substance transport; GO:0071496 cellular response to external stimulus; GO:0043312 neutrophil degranulation; GO:0044238 primary metabolic process; GO:0002263 cell activation involved in immune response; GO:0031668 cellular response to extracellular stimulus; GO:0051641 cellular localization; GO:1905146 lysosomal protein catabolic process; GO:0002366 leukocyte activation involved in immune response; GO:0045184 establishment of protein localization; GO:0042119 neutrophil activation; GO:0070727 cellular macromolecule localization; GO:0045055 regulated exocytosis; GO:0097576 vacuole fusion; GO:0007034 vacuolar transport; GO:0006996 organelle organization; GO:0032463 negative regulation of protein homooligomerization; GO:0009057 macromolecule catabolic process; GO:0001775 cell activation; GO:0042594 response to starvation; GO:0031647 regulation of protein stability; GO:0051128 regulation of cellular component organization; GO:0031667 response to nutrient levels; GO:0006955 immune response; GO:0051179 localization; GO:0009056 catabolic process; GO:0050821 protein stabilization; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; GO:0006887 exocytosis; ","GO:0016020 membrane; GO:0042827 platelet dense granule; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0031088 platelet dense granule membrane; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044754 autolysosome; GO:0005623 cell; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0005765 lysosomal membrane; GO:0070062 extracellular exosome; GO:0031301 integral component of organelle membrane; GO:0031902 late endosome membrane; GO:0005622 intracellular; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:0098791 Golgi subcompartment; GO:0005767 secondary lysosome; GO:0097636 intrinsic component of autophagosome membrane; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0010008 endosome membrane; GO:0005770 late endosome; GO:0030666 endocytic vesicle membrane; GO:0035577 azurophil granule membrane; GO:0044440 endosomal part; GO:0012506 vesicle membrane; GO:0031310 intrinsic component of vacuolar membrane; GO:0043202 lysosomal lumen; GO:0097637 integral component of autophagosome membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0042582 azurophil granule; GO:0043231 intracellular membrane-bounded organelle; GO:0030667 secretory granule membrane; GO:0101003 ficolin-1-rich granule membrane; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043230 extracellular organelle; GO:0031300 intrinsic component of organelle membrane; GO:0005615 extracellular space; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005776 autophagosome; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0030670 phagocytic vesicle membrane; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0048471 perinuclear region of cytoplasm; GO:0005768 endosome; GO:0030141 secretory granule; GO:0030139 endocytic vesicle; GO:0031166 integral component of vacuolar membrane; GO:0000421 autophagosome membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0061742 chaperone-mediated autophagy translocation complex; GO:0098588 bounding membrane of organelle; GO:0070820 tertiary granule; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0045335 phagocytic vesicle; GO:0016021 integral component of membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0005802 trans-Golgi network; GO:0005774 vacuolar membrane; GO:0005794 Golgi apparatus; GO:0031984 organelle subcompartment; GO:0044444 cytoplasmic part; ","GO:0019904 protein domain specific binding; GO:0005515 protein binding; GO:0019899 enzyme binding; GO:0005488 binding; ","K06528","LAMP1_2; lysosomal-associated membrane protein 1/2","hsa04142 Lysosome - Homo sapiens (human); hsa05152 Tuberculosis - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); hsa04140 Autophagy - animal - Homo sapiens (human); "]
["P13489","Ribonuclease inhibitor OS=Homo sapiens OX=9606 GN=RNH1","RNH1",49.973,305.03,50.1,18,47,18,0.986,0.972,0.974,1.01,1.042,1.029,1.051,0.00804,"cyto_nucl\r","GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0048519 negative regulation of biological process; GO:0044237 cellular metabolic process; GO:0051239 regulation of multicellular organismal process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901361 organic cyclic compound catabolic process; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0043170 macromolecule metabolic process; GO:0009987 cellular process; GO:0010468 regulation of gene expression; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:1901342 regulation of vasculature development; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0043086 negative regulation of catalytic activity; GO:0044238 primary metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0009892 negative regulation of metabolic process; GO:0006401 RNA catabolic process; GO:0016070 RNA metabolic process; GO:0019439 aromatic compound catabolic process; GO:1901575 organic substance catabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0050790 regulation of catalytic activity; GO:0022603 regulation of anatomical structure morphogenesis; GO:0006402 mRNA catabolic process; GO:0009057 macromolecule catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0045765 regulation of angiogenesis; GO:0050793 regulation of developmental process; GO:0009056 catabolic process; GO:0016071 mRNA metabolic process; GO:2000026 regulation of multicellular organismal development; GO:0065007 biological regulation; GO:0046700 heterocycle catabolic process; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0032311 angiogenin-PRI complex; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0030234 enzyme regulator activity; GO:0004857 enzyme inhibitor activity; GO:0005488 binding; GO:0008428 ribonuclease inhibitor activity; ","K16634",null,null,"IPR032675; ","\"Leucine-rich repeat domain, L domain-like; \"\r"]
["P13498","Cytochrome b-245 light chain OS=Homo sapiens OX=9606 GN=CYBA","CYBA",21.012,3.8118,12.8,2,2,2,0.841,0.832,0.872,1.163,1.165,1.115,1.353,1.18E-4,"plasma membrane\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:1904385 cellular response to angiotensin; GO:0032680 regulation of tumor necrosis factor production; GO:0042593 glucose homeostasis; GO:0009891 positive regulation of biosynthetic process; GO:0070555 response to interleukin-1; GO:0031347 regulation of defense response; GO:0044237 cellular metabolic process; GO:0045927 positive regulation of growth; GO:0001558 regulation of cell growth; GO:0008152 metabolic process; GO:0065003 macromolecular complex assembly; GO:0044093 positive regulation of molecular function; GO:0034135 regulation of toll-like receptor 2 signaling pathway; GO:0044057 regulation of system process; GO:0071322 cellular response to carbohydrate stimulus; GO:0003044 regulation of systemic arterial blood pressure mediated by a chemical signal; GO:0051716 cellular response to stimulus; GO:0071214 cellular response to abiotic stimulus; GO:0030307 positive regulation of cell growth; GO:0044763 single-organism cellular process; GO:0051353 positive regulation of oxidoreductase activity; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0010243 response to organonitrogen compound; GO:0014823 response to activity; GO:0071480 cellular response to gamma radiation; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0048010 vascular endothelial growth factor receptor signaling pathway; GO:0050665 hydrogen peroxide biosynthetic process; GO:0001819 positive regulation of cytokine production; GO:1901700 response to oxygen-containing compound; GO:0048519 negative regulation of biological process; GO:0042493 response to drug; GO:0042743 hydrogen peroxide metabolic process; GO:0071229 cellular response to acid chemical; GO:0009889 regulation of biosynthetic process; GO:0070482 response to oxygen levels; GO:0010959 regulation of metal ion transport; GO:0033500 carbohydrate homeostasis; GO:0001936 regulation of endothelial cell proliferation; GO:0048878 chemical homeostasis; GO:1903409 reactive oxygen species biosynthetic process; GO:0030100 regulation of endocytosis; GO:0051282 regulation of sequestering of calcium ion; GO:0006950 response to stress; GO:0003014 renal system process; GO:0050766 positive regulation of phagocytosis; GO:0051924 regulation of calcium ion transport; GO:0002376 immune system process; GO:0032101 regulation of response to external stimulus; GO:0010033 response to organic substance; GO:0002263 cell activation involved in immune response; GO:0045055 regulated exocytosis; GO:0002016 regulation of blood volume by renin-angiotensin; GO:0045730 respiratory burst; GO:0031325 positive regulation of cellular metabolic process; GO:0070255 regulation of mucus secretion; GO:0006955 immune response; GO:0003071 renal system process involved in regulation of systemic arterial blood pressure; GO:0003106 negative regulation of glomerular filtration by angiotensin; GO:0008284 positive regulation of cell proliferation; GO:0032930 positive regulation of superoxide anion generation; GO:1900424 regulation of defense response to bacterium; GO:0003012 muscle system process; GO:0009746 response to hexose; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0051046 regulation of secretion; GO:0009058 biosynthetic process; GO:0033860 regulation of NAD(P)H oxidase activity; GO:0007165 signal transduction; GO:1901653 cellular response to peptide; GO:0009893 positive regulation of metabolic process; GO:0034612 response to tumor necrosis factor; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0034121 regulation of toll-like receptor signaling pathway; GO:0043200 response to amino acid; GO:0043902 positive regulation of multi-organism process; GO:0034097 response to cytokine; GO:0051279 regulation of release of sequestered calcium ion into cytosol; GO:0055114 oxidation-reduction process; GO:0023052 signaling; GO:0002444 myeloid leukocyte mediated immunity; GO:0071417 cellular response to organonitrogen compound; GO:0014896 muscle hypertrophy; GO:0032940 secretion by cell; GO:0006954 inflammatory response; GO:0065009 regulation of molecular function; GO:0006952 defense response; GO:0070271 protein complex biogenesis; GO:2000377 regulation of reactive oxygen species metabolic process; GO:0016043 cellular component organization; GO:0071260 cellular response to mechanical stimulus; GO:1903428 positive regulation of reactive oxygen species biosynthetic process; GO:0040008 regulation of growth; GO:0002831 regulation of response to biotic stimulus; GO:2000021 regulation of ion homeostasis; GO:0003083 negative regulation of renal output by angiotensin; GO:0071310 cellular response to organic substance; GO:0010332 response to gamma radiation; GO:0045087 innate immune response; GO:0009612 response to mechanical stimulus; GO:0033993 response to lipid; GO:0042592 homeostatic process; GO:0072593 reactive oxygen species metabolic process; GO:0023056 positive regulation of signaling; GO:0001666 response to hypoxia; GO:0008015 blood circulation; GO:0031960 response to corticosteroid; GO:0010647 positive regulation of cell communication; GO:0071478 cellular response to radiation; GO:0043623 cellular protein complex assembly; GO:0034622 cellular macromolecular complex assembly; GO:0050878 regulation of body fluid levels; GO:0033864 positive regulation of NAD(P)H oxidase activity; GO:0051049 regulation of transport; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:0090279 regulation of calcium ion import; GO:1990776 response to angiotensin; GO:0042554 superoxide anion generation; GO:0044249 cellular biosynthetic process; GO:0043085 positive regulation of catalytic activity; GO:0043933 macromolecular complex subunit organization; GO:0002366 leukocyte activation involved in immune response; GO:0019882 antigen processing and presentation; GO:0042119 neutrophil activation; GO:1901701 cellular response to oxygen-containing compound; GO:0034765 regulation of ion transmembrane transport; GO:0071495 cellular response to endogenous stimulus; GO:0002684 positive regulation of immune system process; GO:0001817 regulation of cytokine production; GO:0071840 cellular component organization or biogenesis; GO:1901654 response to ketone; GO:0006801 superoxide metabolic process; GO:0060627 regulation of vesicle-mediated transport; GO:0045777 positive regulation of blood pressure; GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0007166 cell surface receptor signaling pathway; GO:0032760 positive regulation of tumor necrosis factor production; GO:0009749 response to glucose; GO:0071345 cellular response to cytokine stimulus; GO:0051385 response to mineralocorticoid; GO:0009605 response to external stimulus; GO:0003105 negative regulation of glomerular filtration; GO:0043500 muscle adaptation; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0050678 regulation of epithelial cell proliferation; GO:0048545 response to steroid hormone; GO:0071333 cellular response to glucose stimulus; GO:0009719 response to endogenous stimulus; GO:0001678 cellular glucose homeostasis; GO:0090322 regulation of superoxide metabolic process; GO:0009743 response to carbohydrate; GO:1901652 response to peptide; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0032928 regulation of superoxide anion generation; GO:0014070 response to organic cyclic compound; GO:0070257 positive regulation of mucus secretion; GO:0002443 leukocyte mediated immunity; GO:0001990 regulation of systemic arterial blood pressure by hormone; GO:0000302 response to reactive oxygen species; GO:0043269 regulation of ion transport; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0031323 regulation of cellular metabolic process; GO:0001938 positive regulation of endothelial cell proliferation; GO:0032501 multicellular organismal process; GO:0051341 regulation of oxidoreductase activity; GO:0034762 regulation of transmembrane transport; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0034284 response to monosaccharide; GO:0071230 cellular response to amino acid stimulus; GO:0014805 smooth muscle adaptation; GO:0014895 smooth muscle hypertrophy; GO:0002833 positive regulation of response to biotic stimulus; GO:0002682 regulation of immune system process; GO:0003013 circulatory system process; GO:0051047 positive regulation of secretion; GO:0050794 regulation of cellular process; GO:0002283 neutrophil activation involved in immune response; GO:0042127 regulation of cell proliferation; GO:0017004 cytochrome complex assembly; GO:0009628 response to abiotic stimulus; GO:0045454 cell redox homeostasis; GO:0080134 regulation of response to stress; GO:0032844 regulation of homeostatic process; GO:0051239 regulation of multicellular organismal process; GO:0060341 regulation of cellular localization; GO:0031349 positive regulation of defense response; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; GO:0009966 regulation of signal transduction; GO:1904062 regulation of cation transmembrane transport; GO:0006461 protein complex assembly; GO:0043900 regulation of multi-organism process; GO:0016192 vesicle-mediated transport; GO:0032675 regulation of interleukin-6 production; GO:1903557 positive regulation of tumor necrosis factor superfamily cytokine production; GO:0071496 cellular response to external stimulus; GO:0071407 cellular response to organic cyclic compound; GO:0071326 cellular response to monosaccharide stimulus; GO:0001775 cell activation; GO:0048661 positive regulation of smooth muscle cell proliferation; GO:0036293 response to decreased oxygen levels; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0006887 exocytosis; GO:0001101 response to acid chemical; GO:0071331 cellular response to hexose stimulus; GO:1903555 regulation of tumor necrosis factor superfamily cytokine production; GO:1904044 response to aldosterone; GO:0051241 negative regulation of multicellular organismal process; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0045088 regulation of innate immune response; GO:0032103 positive regulation of response to external stimulus; GO:0003073 regulation of systemic arterial blood pressure; GO:0006979 response to oxidative stress; GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I; GO:0009314 response to radiation; GO:0071479 cellular response to ionizing radiation; GO:1904844 response to L-glutamine; GO:0050764 regulation of phagocytosis; GO:0070887 cellular response to chemical stimulus; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0002274 myeloid leukocyte activation; GO:0002019 regulation of renal output by angiotensin; GO:0098801 regulation of renal system process; GO:0071822 protein complex subunit organization; GO:0003093 regulation of glomerular filtration; GO:0050886 endocrine process; GO:0048002 antigen processing and presentation of peptide antigen; GO:0002446 neutrophil mediated immunity; GO:0019725 cellular homeostasis; GO:0048522 positive regulation of cellular process; GO:0051050 positive regulation of transport; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0043434 response to peptide hormone; GO:1901699 cellular response to nitrogen compound; GO:0032870 cellular response to hormone stimulus; GO:0019222 regulation of metabolic process; GO:0043299 leukocyte degranulation; GO:0008217 regulation of blood pressure; GO:1900426 positive regulation of defense response to bacterium; GO:0071356 cellular response to tumor necrosis factor; GO:0002252 immune effector process; GO:0034123 positive regulation of toll-like receptor signaling pathway; GO:0048660 regulation of smooth muscle cell proliferation; GO:0045807 positive regulation of endocytosis; GO:0050896 response to stimulus; GO:1904845 cellular response to L-glutamine; GO:0055082 cellular chemical homeostasis; GO:0001977 renal system process involved in regulation of blood volume; GO:0009991 response to extracellular stimulus; GO:1903169 regulation of calcium ion transmembrane transport; GO:0071375 cellular response to peptide hormone stimulus; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0032755 positive regulation of interleukin-6 production; GO:0003008 system process; GO:1903426 regulation of reactive oxygen species biosynthetic process; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0034137 positive regulation of toll-like receptor 2 signaling pathway; GO:0010212 response to ionizing radiation; GO:2000379 positive regulation of reactive oxygen species metabolic process; GO:0003084 positive regulation of systemic arterial blood pressure; GO:0010522 regulation of calcium ion transport into cytosol; GO:0031667 response to nutrient levels; GO:0009967 positive regulation of signal transduction; GO:0051128 regulation of cellular component organization; GO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin; GO:0009725 response to hormone; GO:0050679 positive regulation of epithelial cell proliferation; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0030425 dendrite; GO:0097038 perinuclear endoplasmic reticulum; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0043025 neuronal cell body; GO:0032991 macromolecular complex; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0098590 plasma membrane region; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0043005 neuron projection; GO:0030055 cell-substrate junction; GO:0043020 NADPH oxidase complex; GO:0043227 membrane-bounded organelle; GO:0042641 actomyosin; GO:0097458 neuron part; GO:0045177 apical part of cell; GO:0005789 endoplasmic reticulum membrane; GO:0005924 cell-substrate adherens junction; GO:0031226 intrinsic component of plasma membrane; GO:0042995 cell projection; GO:0030666 endocytic vesicle membrane; GO:0044430 cytoskeletal part; GO:0070161 anchoring junction; GO:0012506 vesicle membrane; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0030667 secretory granule membrane; GO:1990204 oxidoreductase complex; GO:0005783 endoplasmic reticulum; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0016324 apical plasma membrane; GO:0031410 cytoplasmic vesicle; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0032432 actin filament bundle; GO:0070821 tertiary granule membrane; GO:0005856 cytoskeleton; GO:1902494 catalytic complex; GO:0044464 cell part; GO:0044425 membrane part; GO:0030670 phagocytic vesicle membrane; GO:0098805 whole membrane; GO:0005912 adherens junction; GO:0048471 perinuclear region of cytoplasm; GO:0005768 endosome; GO:0001725 stress fiber; GO:0030141 secretory granule; GO:0030139 endocytic vesicle; GO:0035579 specific granule membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0070820 tertiary granule; GO:0045335 phagocytic vesicle; GO:0012505 endomembrane system; GO:0097517 contractile actin filament bundle; GO:0015629 actin cytoskeleton; GO:0016021 integral component of membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0005634 nucleus; GO:0036477 somatodendritic compartment; GO:0044459 plasma membrane part; GO:0044432 endoplasmic reticulum part; GO:0042581 specific granule; GO:0044297 cell body; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:0046982 protein heterodimerization activity; GO:0043167 ion binding; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:0017124 SH3 domain binding; GO:0016175 superoxide-generating NADPH oxidase activity; GO:0016491 oxidoreductase activity; GO:0009055 electron carrier activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0020037 heme binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0019904 protein domain specific binding; GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor; GO:0046906 tetrapyrrole binding; ","K08009","CYBA; cytochrome b-245, alpha polypeptide","hsa04670 Leukocyte transendothelial migration - Homo sapiens (human); hsa04380 Osteoclast differentiation - Homo sapiens (human); hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); hsa05140 Leishmaniasis - Homo sapiens (human); hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human); "]
["P13533","Myosin-6 OS=Homo sapiens OX=9606 GN=MYH6","MYH6",223.73,323.31,23.4,38,80,11,0.352,0.346,1.341,1.299,1.261,1.22,1.854,0.204,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0009116 nucleoside metabolic process; GO:0065008 regulation of biological quality; GO:0043009 chordate embryonic development; GO:0060415 muscle tissue morphogenesis; GO:0032989 cellular component morphogenesis; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0030036 actin cytoskeleton organization; GO:0007507 heart development; GO:0003208 cardiac ventricle morphogenesis; GO:0019693 ribose phosphate metabolic process; GO:0044057 regulation of system process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009790 embryo development; GO:0055013 cardiac muscle cell development; GO:0060537 muscle tissue development; GO:0044281 small molecule metabolic process; GO:0055008 cardiac muscle tissue morphogenesis; GO:0044763 single-organism cellular process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0006941 striated muscle contraction; GO:0032501 multicellular organismal process; GO:0048513 animal organ development; GO:0003229 ventricular cardiac muscle tissue development; GO:0051336 regulation of hydrolase activity; GO:0055002 striated muscle cell development; GO:0001701 in utero embryonic development; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0048644 muscle organ morphogenesis; GO:0009887 animal organ morphogenesis; GO:0006464 cellular protein modification process; GO:0009126 purine nucleoside monophosphate metabolic process; GO:0003015 heart process; GO:0003013 circulatory system process; GO:0097435 supramolecular fiber organization; GO:0072359 circulatory system development; GO:0055001 muscle cell development; GO:0044707 single-multicellular organism process; GO:0030049 muscle filament sliding; GO:0055006 cardiac cell development; GO:0048739 cardiac muscle fiber development; GO:0007512 adult heart development; GO:0009259 ribonucleotide metabolic process; GO:0044267 cellular protein metabolic process; GO:0051239 regulation of multicellular organismal process; GO:0055007 cardiac muscle cell differentiation; GO:0009653 anatomical structure morphogenesis; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0055010 ventricular cardiac muscle tissue morphogenesis; GO:0030239 myofibril assembly; GO:1901135 carbohydrate derivative metabolic process; GO:0061061 muscle structure development; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0009119 ribonucleoside metabolic process; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0003231 cardiac ventricle development; GO:0035051 cardiocyte differentiation; GO:0048731 system development; GO:0010927 cellular component assembly involved in morphogenesis; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0003206 cardiac chamber morphogenesis; GO:0006163 purine nucleotide metabolic process; GO:0007522 visceral muscle development; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0002027 regulation of heart rate; GO:0030029 actin filament-based process; GO:0019637 organophosphate metabolic process; GO:0006928 movement of cell or subcellular component; GO:0043412 macromolecule modification; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0030048 actin filament-based movement; GO:0003012 muscle system process; GO:0070252 actin-mediated cell contraction; GO:0042278 purine nucleoside metabolic process; GO:0048747 muscle fiber development; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0003228 atrial cardiac muscle tissue development; GO:0048869 cellular developmental process; GO:0003230 cardiac atrium development; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0006796 phosphate-containing compound metabolic process; GO:0048729 tissue morphogenesis; GO:0022607 cellular component assembly; GO:0006753 nucleoside phosphate metabolic process; GO:0055009 atrial cardiac muscle tissue morphogenesis; GO:0032502 developmental process; GO:0031032 actomyosin structure organization; GO:0009888 tissue development; GO:0003007 heart morphogenesis; GO:1901360 organic cyclic compound metabolic process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:1902589 single-organism organelle organization; GO:0045214 sarcomere organization; GO:0050789 regulation of biological process; GO:0043462 regulation of ATPase activity; GO:0007517 muscle organ development; GO:0065009 regulation of molecular function; GO:1901657 glycosyl compound metabolic process; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0014706 striated muscle tissue development; GO:0008217 regulation of blood pressure; GO:0016043 cellular component organization; GO:0003209 cardiac atrium morphogenesis; GO:0048738 cardiac muscle tissue development; GO:0006725 cellular aromatic compound metabolic process; GO:1903522 regulation of blood circulation; GO:0008016 regulation of heart contraction; GO:0060048 cardiac muscle contraction; GO:0048468 cell development; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0006936 muscle contraction; GO:0070925 organelle assembly; GO:0008015 blood circulation; GO:0034641 cellular nitrogen compound metabolic process; GO:0060047 heart contraction; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0046034 ATP metabolic process; GO:0051146 striated muscle cell differentiation; GO:0003008 system process; GO:0033275 actin-myosin filament sliding; GO:0009792 embryo development ending in birth or egg hatching; GO:0006807 nitrogen compound metabolic process; GO:0006470 protein dephosphorylation; GO:0016311 dephosphorylation; GO:0003205 cardiac chamber development; GO:0046128 purine ribonucleoside metabolic process; GO:0044767 single-organism developmental process; GO:0002026 regulation of the force of heart contraction; GO:0042692 muscle cell differentiation; GO:0009150 purine ribonucleotide metabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0030016 myofibril; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0005859 muscle myosin complex; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0015629 actin cytoskeleton; GO:0044422 organelle part; GO:0099081 supramolecular polymer; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0043226 organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0030017 sarcomere; GO:0016460 myosin II complex; GO:0043292 contractile fiber; GO:0044449 contractile fiber part; GO:0016459 myosin complex; GO:0043234 protein complex; GO:0032982 myosin filament; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0003774 motor activity; GO:0016791 phosphatase activity; GO:0004722 protein serine/threonine phosphatase activity; GO:0019901 protein kinase binding; GO:0017018 myosin phosphatase activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0004721 phosphoprotein phosphatase activity; GO:0016887 ATPase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0008092 cytoskeletal protein binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0000146 microfilament motor activity; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0030898 actin-dependent ATPase activity; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0019900 kinase binding; GO:0005516 calmodulin binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0042578 phosphoric ester hydrolase activity; GO:0016788 hydrolase activity, acting on ester bonds; GO:0042623 ATPase activity, coupled; GO:0003779 actin binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019899 enzyme binding; GO:0036094 small molecule binding; ","K17751","MYH6_7; myosin heavy chain 6/7","hsa04260 Cardiac muscle contraction - Homo sapiens (human); hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human); hsa05414 Dilated cardiomyopathy (DCM) - Homo sapiens (human); hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human); hsa05416 Viral myocarditis - Homo sapiens (human); hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human); hsa05410 Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human); ","IPR002928; IPR004009; IPR027417; IPR001609; IPR027401; ","\"Myosin tail; Myosin, N-terminal, SH3-like; P-loop containing nucleoside triphosphate hydrolase; Myosin head, motor domain; Myosin-like IQ motif-containing domain; \"\r"]
["P13591","Neural cell adhesion molecule 1 OS=Homo sapiens OX=9606 GN=NCAM1","NCAM1",94.573,2.7517,2.3,2,2,2,1.063,1.046,0.994,0.927,1.005,0.978,0.938,0.108,"peroxisome\r","GO:0044409 entry into host; GO:0044700 single organism signaling; GO:0007166 cell surface receptor signaling pathway; GO:0048869 cellular developmental process; GO:0048666 neuron development; GO:0071346 cellular response to interferon-gamma; GO:0044699 single-organism process; GO:0032989 cellular component morphogenesis; GO:0022008 neurogenesis; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0071345 cellular response to cytokine stimulus; GO:0006796 phosphate-containing compound metabolic process; GO:0060333 interferon-gamma-mediated signaling pathway; GO:0022610 biological adhesion; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0032990 cell part morphogenesis; GO:0044093 positive regulation of molecular function; GO:0007155 cell adhesion; GO:0048858 cell projection morphogenesis; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0044419 interspecies interaction between organisms; GO:0070887 cellular response to chemical stimulus; GO:0046718 viral entry into host cell; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0034097 response to cytokine; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0048812 neuron projection morphogenesis; GO:0023052 signaling; GO:0006935 chemotaxis; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0000902 cell morphogenesis; GO:0000165 MAPK cascade; GO:0030260 entry into host cell; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0051336 regulation of hydrolase activity; GO:0030030 cell projection organization; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0051828 entry into other organism involved in symbiotic interaction; GO:0044260 cellular macromolecule metabolic process; GO:0065009 regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0006464 cellular protein modification process; GO:0042330 taxis; GO:0006952 defense response; GO:0040011 locomotion; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0050794 regulation of cellular process; GO:0016310 phosphorylation; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0051806 entry into cell of other organism involved in symbiotic interaction; GO:0019058 viral life cycle; GO:0071310 cellular response to organic substance; GO:0044267 cellular protein metabolic process; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0007411 axon guidance; GO:0045087 innate immune response; GO:0071704 organic substance metabolic process; GO:0000904 cell morphogenesis involved in differentiation; GO:0009653 anatomical structure morphogenesis; GO:0030154 cell differentiation; GO:0006468 protein phosphorylation; GO:0051345 positive regulation of hydrolase activity; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0016032 viral process; GO:0007409 axonogenesis; GO:0007275 multicellular organism development; GO:0019221 cytokine-mediated signaling pathway; GO:0009987 cellular process; GO:0023014 signal transduction by protein phosphorylation; GO:0006950 response to stress; GO:0035556 intracellular signal transduction; GO:0043547 positive regulation of GTPase activity; GO:0048731 system development; GO:0002376 immune system process; GO:0034341 response to interferon-gamma; GO:0010033 response to organic substance; GO:0051701 interaction with host; GO:0044238 primary metabolic process; GO:0031175 neuron projection development; GO:0043085 positive regulation of catalytic activity; GO:0061564 axon development; GO:0030182 neuron differentiation; GO:0006793 phosphorus metabolic process; GO:0097485 neuron projection guidance; GO:0044767 single-organism developmental process; GO:0006928 movement of cell or subcellular component; GO:0043412 macromolecule modification; GO:0006955 immune response; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0009897 external side of plasma membrane; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0043227 membrane-bounded organelle; GO:0098552 side of membrane; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0031225 anchored component of membrane; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044459 plasma membrane part; GO:0009986 cell surface; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0060089 molecular transducer activity; GO:0042802 identical protein binding; GO:0004872 receptor activity; GO:0005085 guanyl-nucleotide exchange factor activity; GO:0005488 binding; GO:0005515 protein binding; GO:0005088 Ras guanyl-nucleotide exchange factor activity; GO:0098772 molecular function regulator; GO:0001618 virus receptor activity; ","K06491","NCAM; neural cell adhesion molecule","hsa04514 Cell adhesion molecules (CAMs) - Homo sapiens (human); hsa05020 Prion diseases - Homo sapiens (human); ","IPR003598; IPR007110; IPR013783; IPR003599; IPR003961; IPR013098; ","Immunoglobulin subtype 2; Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin subtype; Fibronectin type III; Immunoglobulin I-set; \r"]
["P13611","Versican core protein OS=Homo sapiens OX=9606 GN=VCAN","VCAN",372.82,68.92,3.9,15,27,15,1.125,1.141,1.123,0.898,0.846,0.852,0.766,0.000162,"mitochondria\r","GO:0001649 osteoblast differentiation; GO:0016053 organic acid biosynthetic process; GO:0051674 localization of cell; GO:0030206 chondroitin sulfate biosynthetic process; GO:0006024 glycosaminoglycan biosynthetic process; GO:0006026 aminoglycan catabolic process; GO:0048869 cellular developmental process; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0030207 chondroitin sulfate catabolic process; GO:0044237 cellular metabolic process; GO:0044272 sulfur compound biosynthetic process; GO:0030203 glycosaminoglycan metabolic process; GO:0030204 chondroitin sulfate metabolic process; GO:0030166 proteoglycan biosynthetic process; GO:0022610 biological adhesion; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0007155 cell adhesion; GO:0032787 monocarboxylic acid metabolic process; GO:0030198 extracellular matrix organization; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0006790 sulfur compound metabolic process; GO:0009101 glycoprotein biosynthetic process; GO:0001503 ossification; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0030205 dermatan sulfate metabolic process; GO:0009100 glycoprotein metabolic process; GO:0008347 glial cell migration; GO:0048870 cell motility; GO:0032501 multicellular organismal process; GO:0006027 glycosaminoglycan catabolic process; GO:1901575 organic substance catabolic process; GO:0046394 carboxylic acid biosynthetic process; GO:0042063 gliogenesis; GO:0006029 proteoglycan metabolic process; GO:0007417 central nervous system development; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0044273 sulfur compound catabolic process; GO:0040011 locomotion; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:0001501 skeletal system development; GO:0043436 oxoacid metabolic process; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0016477 cell migration; GO:1901566 organonitrogen compound biosynthetic process; GO:0008037 cell recognition; GO:0050651 dermatan sulfate proteoglycan biosynthetic process; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0030208 dermatan sulfate biosynthetic process; GO:0043062 extracellular structure organization; GO:0050654 chondroitin sulfate proteoglycan metabolic process; GO:0044248 cellular catabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0007275 multicellular organism development; GO:0050655 dermatan sulfate proteoglycan metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006022 aminoglycan metabolic process; GO:1903510 mucopolysaccharide metabolic process; GO:0006023 aminoglycan biosynthetic process; GO:0044711 single-organism biosynthetic process; GO:0044712 single-organism catabolic process; GO:0048731 system development; GO:1901136 carbohydrate derivative catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:1901565 organonitrogen compound catabolic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044767 single-organism developmental process; GO:0009057 macromolecule catabolic process; GO:0019752 carboxylic acid metabolic process; GO:0044283 small molecule biosynthetic process; GO:0006928 movement of cell or subcellular component; GO:0050650 chondroitin sulfate proteoglycan biosynthetic process; GO:0051179 localization; GO:0072330 monocarboxylic acid biosynthetic process; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0005764 lysosome; GO:0044431 Golgi apparatus part; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0005796 Golgi lumen; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0043202 lysosomal lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031012 extracellular matrix; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005578 proteinaceous extracellular matrix; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:0005201 extracellular matrix structural constituent; GO:0097367 carbohydrate derivative binding; GO:0005488 binding; GO:0043167 ion binding; GO:0005540 hyaluronic acid binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0030246 carbohydrate binding; GO:0005515 protein binding; GO:0005509 calcium ion binding; GO:0005539 glycosaminoglycan binding; GO:0005198 structural molecule activity; ","K06793","VCAN; versican core protein","hsa04514 Cell adhesion molecules (CAMs) - Homo sapiens (human); ","IPR007110; IPR016187; IPR001881; IPR003599; IPR000742; IPR016186; IPR001304; IPR033987; IPR000436; IPR013783; IPR013106; IPR000538; ","\"Immunoglobulin-like domain; C-type lectin fold; EGF-like calcium-binding domain; Immunoglobulin subtype; EGF-like domain; C-type lectin-like/link domain; C-type lectin-like; Aggrecan/versican, C-type lectin-like domain; Sushi/SCR/CCP domain; Immunoglobulin-like fold; Immunoglobulin V-set domain; Link domain; \"\r"]
["P13639","Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2","EEF2",95.337,255.59,44.2,38,106,37,0.832,0.836,0.85,1.168,1.166,1.152,1.384,9.89e-07,"cytoplasm\r","GO:0045321 leukocyte activation; GO:0032270 positive regulation of cellular protein metabolic process; GO:0006518 peptide metabolic process; GO:0010608 posttranscriptional regulation of gene expression; GO:0009891 positive regulation of biosynthetic process; GO:0044237 cellular metabolic process; GO:0009605 response to external stimulus; GO:0008213 protein alkylation; GO:0008152 metabolic process; GO:0009719 response to endogenous stimulus; GO:0070848 response to growth factor; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0007399 nervous system development; GO:0002244 hematopoietic progenitor cell differentiation; GO:0051716 cellular response to stimulus; GO:0014070 response to organic cyclic compound; GO:0002443 leukocyte mediated immunity; GO:0080090 regulation of primary metabolic process; GO:0060537 muscle tissue development; GO:0000302 response to reactive oxygen species; GO:0050879 multicellular organismal movement; GO:0044763 single-organism cellular process; GO:0006941 striated muscle contraction; GO:0002520 immune system development; GO:0031323 regulation of cellular metabolic process; GO:0060538 skeletal muscle organ development; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:0048513 animal organ development; GO:0010243 response to organonitrogen compound; GO:0042063 gliogenesis; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:1901698 response to nitrogen compound; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0044707 single-multicellular organism process; GO:0002283 neutrophil activation involved in immune response; GO:0034976 response to endoplasmic reticulum stress; GO:1901700 response to oxygen-containing compound; GO:0044267 cellular protein metabolic process; GO:0032355 response to estradiol; GO:0042493 response to drug; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0006479 protein methylation; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0051171 regulation of nitrogen compound metabolic process; GO:0061061 muscle structure development; GO:0007275 multicellular organism development; GO:1990089 response to nerve growth factor; GO:0006950 response to stress; GO:0006414 translational elongation; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0017183 peptidyl-diphthamide biosynthetic process from peptidyl-histidine; GO:0008283 cell proliferation; GO:0002376 immune system process; GO:0097305 response to alcohol; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0007584 response to nutrient; GO:0002263 cell activation involved in immune response; GO:1901576 organic substance biosynthetic process; GO:0003009 skeletal muscle contraction; GO:0034248 regulation of cellular amide metabolic process; GO:0018202 peptidyl-histidine modification; GO:0045055 regulated exocytosis; GO:0051247 positive regulation of protein metabolic process; GO:0042542 response to hydrogen peroxide; GO:0043414 macromolecule methylation; GO:0031325 positive regulation of cellular metabolic process; GO:0001775 cell activation; GO:0051179 localization; GO:0006955 immune response; GO:0031328 positive regulation of cellular biosynthetic process; GO:0043412 macromolecule modification; GO:0006887 exocytosis; GO:1901564 organonitrogen compound metabolic process; GO:0003012 muscle system process; GO:0001101 response to acid chemical; GO:2000765 regulation of cytoplasmic translation; GO:0048869 cellular developmental process; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0071363 cellular response to growth factor stimulus; GO:0051593 response to folic acid; GO:0032259 methylation; GO:0051234 establishment of localization; GO:0002931 response to ischemia; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0006979 response to oxidative stress; GO:0010035 response to inorganic substance; GO:0006412 translation; GO:0007519 skeletal muscle tissue development; GO:0070887 cellular response to chemical stimulus; GO:0033273 response to vitamin; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0009888 tissue development; GO:0031326 regulation of cellular biosynthetic process; GO:0045727 positive regulation of translation; GO:0043043 peptide biosynthetic process; GO:0002446 neutrophil mediated immunity; GO:0048522 positive regulation of cellular process; GO:0043603 cellular amide metabolic process; GO:1990416 cellular response to brain-derived neurotrophic factor stimulus; GO:0002444 myeloid leukocyte mediated immunity; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0007517 muscle organ development; GO:0032940 secretion by cell; GO:0007568 aging; GO:0019222 regulation of metabolic process; GO:0043299 leukocyte degranulation; GO:0014009 glial cell proliferation; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0014706 striated muscle tissue development; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0045471 response to ethanol; GO:0071310 cellular response to organic substance; GO:0050896 response to stimulus; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0009991 response to extracellular stimulus; GO:0033993 response to lipid; GO:0030154 cell differentiation; GO:0006936 muscle contraction; GO:0050881 musculoskeletal movement; GO:0035914 skeletal muscle cell differentiation; GO:0034641 cellular nitrogen compound metabolic process; GO:0036230 granulocyte activation; GO:0009059 macromolecule biosynthetic process; GO:0017182 peptidyl-diphthamide metabolic process; GO:0009987 cellular process; GO:0003008 system process; GO:1990090 cellular response to nerve growth factor stimulus; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:2000767 positive regulation of cytoplasmic translation; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0030097 hemopoiesis; GO:0048534 hematopoietic or lymphoid organ development; GO:0002366 leukocyte activation involved in immune response; GO:0018193 peptidyl-amino acid modification; GO:0042119 neutrophil activation; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0006417 regulation of translation; GO:0071495 cellular response to endogenous stimulus; GO:0034250 positive regulation of cellular amide metabolic process; GO:0010467 gene expression; GO:0031667 response to nutrient levels; GO:0043604 amide biosynthetic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0034774 secretory granule lumen; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0098857 membrane microdomain; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0099503 secretory vesicle; GO:0098589 membrane region; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0045121 membrane raft; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0005840 ribosome; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0016234 inclusion body; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0031012 extracellular matrix; GO:0043226 organelle; GO:0005634 nucleus; GO:0042788 polysomal ribosome; GO:0060205 cytoplasmic vesicle lumen; GO:0016235 aggresome; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0005844 polysome; ","GO:0051015 actin filament binding; GO:1901265 nucleoside phosphate binding; GO:0003746 translation elongation factor activity; GO:0019901 protein kinase binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0008092 cytoskeletal protein binding; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0003924 GTPase activity; GO:0045296 cadherin binding; GO:0043168 anion binding; GO:0019001 guanyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003723 RNA binding; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0019900 kinase binding; GO:0017111 nucleoside-triphosphatase activity; GO:0019843 rRNA binding; GO:0043022 ribosome binding; GO:0008135 translation factor activity, RNA binding; GO:0050839 cell adhesion molecule binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0002039 p53 binding; GO:0008097 5S rRNA binding; GO:0003676 nucleic acid binding; GO:0003779 actin binding; GO:0032555 purine ribonucleotide binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0043021 ribonucleoprotein complex binding; GO:0019899 enzyme binding; GO:0036094 small molecule binding; GO:0032403 protein complex binding; ","K03234","EEF2; elongation factor 2","hsa04921 Oxytocin signaling pathway - Homo sapiens (human); hsa04152 AMPK signaling pathway - Homo sapiens (human); ","IPR027417; IPR000795; IPR005517; IPR005225; IPR000640; IPR004161; IPR020568; IPR009022; IPR014721; IPR009000; ","\"P-loop containing nucleoside triphosphate hydrolase; Transcription factor, GTP-binding domain; Translation elongation factor EFG/EF2, domain IV; Small GTP-binding protein domain; Translation elongation factor EFG, V domain; Translation elongation factor EFTu-like, domain 2; Ribosomal protein S5 domain 2-type fold; Elongation factor G, III-V domain; Ribosomal protein S5 domain 2-type fold, subgroup; Translation protein, beta-barrel domain; \"\r"]
["P13667","Protein disulfide-isomerase A4 OS=Homo sapiens OX=9606 GN=PDIA4","PDIA4",72.932,192.16,44.2,28,47,28,1.037,1.041,1.051,0.956,0.956,0.97,0.921,0.000198,"extracellular\r","GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0051716 cellular response to stimulus; GO:0065008 regulation of biological quality; GO:0034976 response to endoplasmic reticulum stress; GO:0006950 response to stress; GO:0045454 cell redox homeostasis; GO:0061077 chaperone-mediated protein folding; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0019725 cellular homeostasis; GO:0071702 organic substance transport; GO:0050896 response to stimulus; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006810 transport; GO:0045184 establishment of protein localization; GO:0006457 protein folding; GO:0042592 homeostatic process; GO:0050789 regulation of biological process; GO:1902578 single-organism localization; GO:0032940 secretion by cell; GO:0009306 protein secretion; GO:0051179 localization; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0009987 cellular process; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0065007 biological regulation; ","GO:0097708 intracellular vesicle; GO:0005788 endoplasmic reticulum lumen; GO:0043229 intracellular organelle; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0042470 melanosome; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0048770 pigment granule; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044432 endoplasmic reticulum part; GO:0044464 cell part; GO:0005622 intracellular; GO:0009986 cell surface; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds; GO:0003723 RNA binding; GO:0016853 isomerase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0016860 intramolecular oxidoreductase activity; GO:0003756 protein disulfide isomerase activity; ","K09582","PDIA4; protein disulfide-isomerase A4 [EC:5.3.4.1]","hsa05110 Vibrio cholerae infection - Homo sapiens (human); hsa04918 Thyroid hormone synthesis - Homo sapiens (human); hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); ","IPR005788; IPR013766; IPR012336; ","Disulphide isomerase; Thioredoxin domain; Thioredoxin-like fold; \r"]
["P13671","Complement component C6 OS=Homo sapiens OX=9606 GN=C6","C6",104.79,98.494,20.4,18,20,18,0.981,0.978,0.952,1.063,1.002,1.042,1.067,0.0305,"extracellular\r","GO:0016064 immunoglobulin mediated immune response; GO:0032270 positive regulation of cellular protein metabolic process; GO:0002922 positive regulation of humoral immune response; GO:0043009 chordate embryonic development; GO:2000259 positive regulation of protein activation cascade; GO:0044699 single-organism process; GO:0031347 regulation of defense response; GO:0006956 complement activation; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0009893 positive regulation of metabolic process; GO:0002250 adaptive immune response; GO:1904018 positive regulation of vasculature development; GO:0006958 complement activation, classical pathway; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009790 embryo development; GO:0002697 regulation of immune effector process; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0002443 leukocyte mediated immunity; GO:0080090 regulation of primary metabolic process; GO:0048522 positive regulation of cellular process; GO:0031323 regulation of cellular metabolic process; GO:0001969 regulation of activation of membrane attack complex; GO:0032501 multicellular organismal process; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0050776 regulation of immune response; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0001701 in utero embryonic development; GO:0048583 regulation of response to stimulus; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0045765 regulation of angiogenesis; GO:0002682 regulation of immune system process; GO:0006952 defense response; GO:0045917 positive regulation of complement activation; GO:1903317 regulation of protein maturation; GO:0051094 positive regulation of developmental process; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0050794 regulation of cellular process; GO:0030449 regulation of complement activation; GO:0044707 single-multicellular organism process; GO:2000257 regulation of protein activation cascade; GO:0019835 cytolysis; GO:1903319 positive regulation of protein maturation; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0002920 regulation of humoral immune response; GO:0001970 positive regulation of activation of membrane attack complex; GO:0002673 regulation of acute inflammatory response; GO:0006959 humoral immune response; GO:0080134 regulation of response to stress; GO:0050896 response to stimulus; GO:0045766 positive regulation of angiogenesis; GO:0045087 innate immune response; GO:0051239 regulation of multicellular organismal process; GO:0071704 organic substance metabolic process; GO:0019724 B cell mediated immunity; GO:0045862 positive regulation of proteolysis; GO:0010628 positive regulation of gene expression; GO:0007275 multicellular organism development; GO:0002449 lymphocyte mediated immunity; GO:0050778 positive regulation of immune response; GO:0009987 cellular process; GO:0002253 activation of immune response; GO:0006950 response to stress; GO:0002699 positive regulation of immune effector process; GO:0009792 embryo development ending in birth or egg hatching; GO:1901342 regulation of vasculature development; GO:0002376 immune system process; GO:0072376 protein activation cascade; GO:0032101 regulation of response to external stimulus; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0010954 positive regulation of protein processing; GO:0051247 positive regulation of protein metabolic process; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0031325 positive regulation of cellular metabolic process; GO:0002684 positive regulation of immune system process; GO:0050727 regulation of inflammatory response; GO:0070613 regulation of protein processing; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0048584 positive regulation of response to stimulus; GO:0006955 immune response; GO:0050793 regulation of developmental process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0031226 intrinsic component of plasma membrane; GO:0044421 extracellular region part; GO:0098796 membrane protein complex; GO:0071944 cell periphery; GO:0046930 pore complex; GO:0098797 plasma membrane protein complex; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0044459 plasma membrane part; GO:0044464 cell part; GO:0044425 membrane part; GO:1903561 extracellular vesicle; GO:0005579 membrane attack complex; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0005515 protein binding; GO:0005488 binding; ","K03995","C6; complement component 6","hsa05322 Systemic lupus erythematosus - Homo sapiens (human); hsa04610 Complement and coagulation cascades - Homo sapiens (human); hsa05020 Prion diseases - Homo sapiens (human); ","IPR020864; IPR000436; IPR002350; IPR003884; ","Membrane attack complex component/perforin (MACPF) domain; Sushi/SCR/CCP domain; Kazal domain; Factor I / membrane attack complex; \r"]
["P13674","Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1","P4HA1",61.049,36.059,19.9,9,13,9,1.104,1.115,1.102,0.845,0.961,0.827,0.793,0.038,"endoplasmic reticulum\r","GO:0016043 cellular component organization; GO:0030199 collagen fibril organization; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0006575 cellular modified amino acid metabolic process; GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline; GO:0043062 extracellular structure organization; GO:0019471 4-hydroxyproline metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0030198 extracellular matrix organization; GO:0009987 cellular process; GO:0018126 protein hydroxylation; GO:0019511 peptidyl-proline hydroxylation; GO:0071822 protein complex subunit organization; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:0018208 peptidyl-proline modification; GO:0044238 primary metabolic process; GO:1901605 alpha-amino acid metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0018193 peptidyl-amino acid modification; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0006464 cellular protein modification process; GO:0006082 organic acid metabolic process; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:0097435 supramolecular fiber organization; GO:0043436 oxoacid metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0005788 endoplasmic reticulum lumen; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0044432 endoplasmic reticulum part; GO:0016222 procollagen-proline 4-dioxygenase complex; GO:0044464 cell part; GO:0005622 intracellular; GO:1990204 oxidoreductase complex; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0019842 vitamin binding; GO:0005506 iron ion binding; GO:0031418 L-ascorbic acid binding; GO:0031543 peptidyl-proline dioxygenase activity; GO:0043167 ion binding; GO:0043177 organic acid binding; GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; GO:0005515 protein binding; GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; GO:0004656 procollagen-proline 4-dioxygenase activity; GO:0048029 monosaccharide binding; GO:0016491 oxidoreductase activity; GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen; GO:0031406 carboxylic acid binding; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0019798 procollagen-proline dioxygenase activity; GO:0051213 dioxygenase activity; GO:0005488 binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0030246 carbohydrate binding; GO:0043168 anion binding; GO:0031545 peptidyl-proline 4-dioxygenase activity; GO:0036094 small molecule binding; ","K00472","P4HA; prolyl 4-hydroxylase [EC:1.14.11.2]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00330 Arginine and proline metabolism - Homo sapiens (human); ","IPR006620; IPR013547; IPR005123; IPR011990; IPR013026; ","\"Prolyl 4-hydroxylase, alpha subunit; Prolyl 4-hydroxylase alpha-subunit, N-terminal; Oxoglutarate/iron-dependent dioxygenase; Tetratricopeptide-like helical domain; Tetratricopeptide repeat-containing domain; \"\r"]
["P13686","Tartrate-resistant acid phosphatase type 5 OS=Homo sapiens OX=9606 GN=ACP5","ACP5",36.598,6.2575,5.8,1,1,1,0.95,1.083,1.024,0.948,0.973,1.031,0.966,0.493,"extracellular\r","GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0044699 single-organism process; GO:0006807 nitrogen compound metabolic process; GO:0016311 dephosphorylation; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0006766 vitamin metabolic process; GO:0046483 heterocycle metabolic process; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0006771 riboflavin metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009987 cellular process; GO:0006767 water-soluble vitamin metabolic process; GO:0042726 flavin-containing compound metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0005773 vacuole; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0000323 lytic vacuole; ","GO:0005506 iron ion binding; GO:0003993 acid phosphatase activity; GO:0008199 ferric iron binding; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0042578 phosphoric ester hydrolase activity; GO:0016791 phosphatase activity; GO:0005488 binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0043167 ion binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0016787 hydrolase activity; GO:0008198 ferrous iron binding; ","K14379","ACP5; tartrate-resistant acid phosphatase type 5 [EC:3.1.3.2]","hsa04142 Lysosome - Homo sapiens (human); hsa04380 Osteoclast differentiation - Homo sapiens (human); hsa05323 Rheumatoid arthritis - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00740 Riboflavin metabolism - Homo sapiens (human); ","IPR029052; IPR004843; ","\"Metallo-dependent phosphatase-like; Calcineurin-like phosphoesterase domain, ApaH type; \"\r"]
["P13693","Translationally-controlled tumor protein OS=Homo sapiens OX=9606 GN=TPT1","TPT1",19.595,61.15,43.6,8,25,8,0.825,0.847,0.862,1.163,1.123,1.177,1.367,8.01e-05,"cyto_nucl\r","GO:0065008 regulation of biological quality; GO:0010941 regulation of cell death; GO:0072503 cellular divalent inorganic cation homeostasis; GO:0009968 negative regulation of signal transduction; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0009607 response to biotic stimulus; GO:0051234 establishment of localization; GO:0009605 response to external stimulus; GO:2001233 regulation of apoptotic signaling pathway; GO:0010646 regulation of cell communication; GO:2001243 negative regulation of intrinsic apoptotic signaling pathway; GO:0055065 metal ion homeostasis; GO:1902229 regulation of intrinsic apoptotic signaling pathway in response to DNA damage; GO:0044419 interspecies interaction between organisms; GO:0032502 developmental process; GO:0050801 ion homeostasis; GO:0055074 calcium ion homeostasis; GO:0044763 single-organism cellular process; GO:0098771 inorganic ion homeostasis; GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage; GO:0019725 cellular homeostasis; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0051704 multi-organism process; GO:0006874 cellular calcium ion homeostasis; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0006810 transport; GO:2001021 negative regulation of response to DNA damage stimulus; GO:0050789 regulation of biological process; GO:0080135 regulation of cellular response to stress; GO:1902532 negative regulation of intracellular signal transduction; GO:0048583 regulation of response to stimulus; GO:0072507 divalent inorganic cation homeostasis; GO:0060548 negative regulation of cell death; GO:0009615 response to virus; GO:0050794 regulation of cellular process; GO:0043069 negative regulation of programmed cell death; GO:0072511 divalent inorganic cation transport; GO:2001020 regulation of response to DNA damage stimulus; GO:0030001 metal ion transport; GO:0030003 cellular cation homeostasis; GO:0043067 regulation of programmed cell death; GO:0043207 response to external biotic stimulus; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0080134 regulation of response to stress; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0055082 cellular chemical homeostasis; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0043066 negative regulation of apoptotic process; GO:0055080 cation homeostasis; GO:0006812 cation transport; GO:0006816 calcium ion transport; GO:0016032 viral process; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:1902531 regulation of intracellular signal transduction; GO:0048585 negative regulation of response to stimulus; GO:0006873 cellular ion homeostasis; GO:0044767 single-organism developmental process; GO:0006811 ion transport; GO:2001242 regulation of intrinsic apoptotic signaling pathway; GO:0006875 cellular metal ion homeostasis; GO:0051179 localization; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; GO:0070838 divalent metal ion transport; ","GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005770 late endosome; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0005771 multivesicular body; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0008092 cytoskeletal protein binding; GO:0008017 microtubule binding; GO:0005488 binding; GO:0043167 ion binding; GO:0003676 nucleic acid binding; GO:0015631 tubulin binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0005509 calcium ion binding; ",{"$nulls":3},"IPR011323; IPR011057; ","Mss4/translationally controlled tumour-associated TCTP; Mss4-like; \r"]
["P13716","Delta-aminolevulinic acid dehydratase OS=Homo sapiens OX=9606 GN=ALAD","ALAD",36.294,39.389,33,10,15,10,0.82,1.101,0.867,1.097,1.071,1.006,1.138,0.218,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:0045321 leukocyte activation; GO:0046685 response to arsenic-containing substance; GO:0071345 cellular response to cytokine stimulus; GO:0044237 cellular metabolic process; GO:0009607 response to biotic stimulus; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0009635 response to herbicide; GO:0065003 macromolecular complex assembly; GO:0048545 response to steroid hormone; GO:0009719 response to endogenous stimulus; GO:0046689 response to mercury ion; GO:0051597 response to methylmercury; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0051716 cellular response to stimulus; GO:0014070 response to organic cyclic compound; GO:0002443 leukocyte mediated immunity; GO:0018130 heterocycle biosynthetic process; GO:0044763 single-organism cellular process; GO:0071353 cellular response to interleukin-4; GO:0051704 multi-organism process; GO:0006810 transport; GO:0010243 response to organonitrogen compound; GO:0014823 response to activity; GO:0044710 single-organism metabolic process; GO:1901698 response to nitrogen compound; GO:0033014 tetrapyrrole biosynthetic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0010044 response to aluminum ion; GO:0002283 neutrophil activation involved in immune response; GO:0051260 protein homooligomerization; GO:0009628 response to abiotic stimulus; GO:1901700 response to oxygen-containing compound; GO:0051259 protein oligomerization; GO:0042493 response to drug; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0010039 response to iron ion; GO:0010043 response to zinc ion; GO:0019438 aromatic compound biosynthetic process; GO:0070482 response to oxygen levels; GO:0070670 response to interleukin-4; GO:0070542 response to fatty acid; GO:0009617 response to bacterium; GO:0006461 protein complex assembly; GO:0006950 response to stress; GO:0044711 single-organism biosynthetic process; GO:0032496 response to lipopolysaccharide; GO:0016192 vesicle-mediated transport; GO:0006779 porphyrin-containing compound biosynthetic process; GO:0002376 immune system process; GO:0097305 response to alcohol; GO:0010033 response to organic substance; GO:0010269 response to selenium ion; GO:0007584 response to nutrient; GO:0002263 cell activation involved in immune response; GO:1901576 organic substance biosynthetic process; GO:0045055 regulated exocytosis; GO:0071284 cellular response to lead ion; GO:0001775 cell activation; GO:0036293 response to decreased oxygen levels; GO:0071248 cellular response to metal ion; GO:0051179 localization; GO:0006955 immune response; GO:0006887 exocytosis; GO:1901564 organonitrogen compound metabolic process; GO:0051188 cofactor biosynthetic process; GO:0046148 pigment biosynthetic process; GO:0001101 response to acid chemical; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0033197 response to vitamin E; GO:0010266 response to vitamin B1; GO:0051234 establishment of localization; GO:0022607 cellular component assembly; GO:0006979 response to oxidative stress; GO:0046686 response to cadmium ion; GO:0009314 response to radiation; GO:0010035 response to inorganic substance; GO:0033273 response to vitamin; GO:0070887 cellular response to chemical stimulus; GO:0002274 myeloid leukocyte activation; GO:0043200 response to amino acid; GO:0071822 protein complex subunit organization; GO:0034097 response to cytokine; GO:0002237 response to molecule of bacterial origin; GO:0009636 response to toxic substance; GO:0002446 neutrophil mediated immunity; GO:1901360 organic cyclic compound metabolic process; GO:0051384 response to glucocorticoid; GO:0010038 response to metal ion; GO:0002444 myeloid leukocyte mediated immunity; GO:0051186 cofactor metabolic process; GO:0042221 response to chemical; GO:0032940 secretion by cell; GO:0033013 tetrapyrrole metabolic process; GO:0071241 cellular response to inorganic substance; GO:0010288 response to lead ion; GO:0043299 leukocyte degranulation; GO:0070271 protein complex biogenesis; GO:0070541 response to platinum ion; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0002252 immune effector process; GO:0006783 heme biosynthetic process; GO:0045471 response to ethanol; GO:0071310 cellular response to organic substance; GO:0046501 protoporphyrinogen IX metabolic process; GO:0043207 response to external biotic stimulus; GO:1901566 organonitrogen compound biosynthetic process; GO:0042168 heme metabolic process; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0071704 organic substance metabolic process; GO:0009991 response to extracellular stimulus; GO:0033993 response to lipid; GO:0006778 porphyrin-containing compound metabolic process; GO:0006782 protoporphyrinogen IX biosynthetic process; GO:0001666 response to hypoxia; GO:0031960 response to corticosteroid; GO:0034641 cellular nitrogen compound metabolic process; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0042440 pigment metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0043312 neutrophil degranulation; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0002366 leukocyte activation involved in immune response; GO:0010212 response to ionizing radiation; GO:0042119 neutrophil activation; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0032025 response to cobalt ion; GO:0031667 response to nutrient levels; GO:0009725 response to hormone; GO:0071840 cellular component organization or biogenesis; ","GO:0034774 secretory granule lumen; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0042802 identical protein binding; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0016829 lyase activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0016836 hydro-lyase activity; GO:0005515 protein binding; GO:0008270 zinc ion binding; GO:0032791 lead ion binding; GO:0004655 porphobilinogen synthase activity; GO:0016835 carbon-oxygen lyase activity; ","K01698","hemB; porphobilinogen synthase [EC:4.2.1.24]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00860 Porphyrin and chlorophyll metabolism - Homo sapiens (human); ","IPR013785; ","Aldolase-type TIM barrel; \r"]
["P13746","HLA class I histocompatibility antigen, A-11 alpha chain OS=Homo sapiens OX=9606 GN=HLA-A","HLA-A",40.936,116.82,39.2,15,31,2,1.143,0.742,1.043,1.115,1.049,0.912,1.051,0.688,"extracellular\r","GO:0044700 single organism signaling; GO:0007166 cell surface receptor signaling pathway; GO:0002698 negative regulation of immune effector process; GO:0071346 cellular response to interferon-gamma; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; GO:0031347 regulation of defense response; GO:0071345 cellular response to cytokine stimulus; GO:0060333 interferon-gamma-mediated signaling pathway; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0045088 regulation of innate immune response; GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I; GO:0050777 negative regulation of immune response; GO:0044419 interspecies interaction between organisms; GO:0002697 regulation of immune effector process; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0070887 cellular response to chemical stimulus; GO:0051716 cellular response to stimulus; GO:0034097 response to cytokine; GO:0048002 antigen processing and presentation of peptide antigen; GO:0034340 response to type I interferon; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0002716 negative regulation of natural killer cell mediated immunity; GO:0023052 signaling; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0002683 negative regulation of immune system process; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0048583 regulation of response to stimulus; GO:0042269 regulation of natural killer cell mediated cytotoxicity; GO:0002682 regulation of immune system process; GO:0006952 defense response; GO:0050794 regulation of cellular process; GO:0060337 type I interferon signaling pathway; GO:0031341 regulation of cell killing; GO:0071310 cellular response to organic substance; GO:0002704 negative regulation of leukocyte mediated immunity; GO:0002715 regulation of natural killer cell mediated immunity; GO:0080134 regulation of response to stress; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0002706 regulation of lymphocyte mediated immunity; GO:0045087 innate immune response; GO:0045953 negative regulation of natural killer cell mediated cytotoxicity; GO:0016032 viral process; GO:0002707 negative regulation of lymphocyte mediated immunity; GO:0071357 cellular response to type I interferon; GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; GO:0019221 cytokine-mediated signaling pathway; GO:0009987 cellular process; GO:0031348 negative regulation of defense response; GO:0001910 regulation of leukocyte mediated cytotoxicity; GO:0006950 response to stress; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:0031342 negative regulation of cell killing; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0034341 response to interferon-gamma; GO:0048585 negative regulation of response to stimulus; GO:0045824 negative regulation of innate immune response; GO:0002703 regulation of leukocyte mediated immunity; GO:0019882 antigen processing and presentation; GO:0042270 protection from natural killer cell mediated cytotoxicity; GO:0006955 immune response; GO:0001911 negative regulation of leukocyte mediated cytotoxicity; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0005622 intracellular; GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0098552 side of membrane; GO:0010008 endosome membrane; GO:0031226 intrinsic component of plasma membrane; GO:0030666 endocytic vesicle membrane; GO:0098797 plasma membrane protein complex; GO:0012506 vesicle membrane; GO:0044440 endosomal part; GO:0030135 coated vesicle; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0098553 lumenal side of endoplasmic reticulum membrane; GO:0042612 MHC class I protein complex; GO:0030133 transport vesicle; GO:0043234 protein complex; GO:0030176 integral component of endoplasmic reticulum membrane; GO:0030658 transport vesicle membrane; GO:0005783 endoplasmic reticulum; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0042611 MHC protein complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0055038 recycling endosome membrane; GO:0030662 coated vesicle membrane; GO:0055037 recycling endosome; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0030670 phagocytic vesicle membrane; GO:0044431 Golgi apparatus part; GO:0031227 intrinsic component of endoplasmic reticulum membrane; GO:0005768 endosome; GO:0031901 early endosome membrane; GO:0030139 endocytic vesicle; GO:0012507 ER to Golgi transport vesicle membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0045335 phagocytic vesicle; GO:0030134 ER to Golgi transport vesicle; GO:0016021 integral component of membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0044432 endoplasmic reticulum part; GO:0009986 cell surface; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:0030881 beta-2-microglobulin binding; GO:0046977 TAP binding; GO:0042277 peptide binding; GO:0005488 binding; GO:0005515 protein binding; GO:0033218 amide binding; GO:0042605 peptide antigen binding; GO:0003823 antigen binding; ","K06751","MHC1; major histocompatibility complex, class I","hsa05330 Allograft rejection - Homo sapiens (human); hsa04650 Natural killer cell mediated cytotoxicity - Homo sapiens (human); hsa04218 Cellular senescence - Homo sapiens (human); hsa05168 Herpes simplex infection - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa05416 Viral myocarditis - Homo sapiens (human); hsa05167 Kaposi's sarcoma-associated herpesvirus infection - Homo sapiens (human); hsa05203 Viral carcinogenesis - Homo sapiens (human); hsa05166 HTLV-I infection - Homo sapiens (human); hsa04144 Endocytosis - Homo sapiens (human); hsa04612 Antigen processing and presentation - Homo sapiens (human); hsa04940 Type I diabetes mellitus - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); hsa04514 Cell adhesion molecules (CAMs) - Homo sapiens (human); hsa05332 Graft-versus-host disease - Homo sapiens (human); hsa05320 Autoimmune thyroid disease - Homo sapiens (human); ","IPR007110; IPR013783; IPR010579; IPR011161; IPR011162; IPR001039; IPR003597; ","\"Immunoglobulin-like domain; Immunoglobulin-like fold; MHC class I, alpha chain, C-terminal; MHC class I-like antigen recognition-like; MHC classes I/II-like antigen recognition protein; MHC class I alpha chain, alpha1 alpha2 domains; Immunoglobulin C1-set; \"\r"]
["P13747","HLA class I histocompatibility antigen, alpha chain E OS=Homo sapiens OX=9606 GN=HLA-E","HLA-E",40.156,11.95,12,4,8,2,1.065,0.879,1.115,1.003,1.005,0.94,0.964,0.693,"extracellular\r","GO:0044700 single organism signaling; GO:0002694 regulation of leukocyte activation; GO:0045321 leukocyte activation; GO:0032944 regulation of mononuclear cell proliferation; GO:0032680 regulation of tumor necrosis factor production; GO:0007166 cell surface receptor signaling pathway; GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0002698 negative regulation of immune effector process; GO:0032656 regulation of interleukin-13 production; GO:0098542 defense response to other organism; GO:0032760 positive regulation of tumor necrosis factor production; GO:0032679 regulation of TRAIL production; GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; GO:0031347 regulation of defense response; GO:0071345 cellular response to cytokine stimulus; GO:0009607 response to biotic stimulus; GO:0042110 T cell activation; GO:0009605 response to external stimulus; GO:0031343 positive regulation of cell killing; GO:0032673 regulation of interleukin-4 production; GO:0032946 positive regulation of mononuclear cell proliferation; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0002709 regulation of T cell mediated immunity; GO:0051716 cellular response to stimulus; GO:0046641 positive regulation of alpha-beta T cell proliferation; GO:0002639 positive regulation of immunoglobulin production; GO:0019730 antimicrobial humoral response; GO:0044763 single-organism cellular process; GO:0034340 response to type I interferon; GO:0050670 regulation of lymphocyte proliferation; GO:0002717 positive regulation of natural killer cell mediated immunity; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0048583 regulation of response to stimulus; GO:0050714 positive regulation of protein secretion; GO:0046634 regulation of alpha-beta T cell activation; GO:0051223 regulation of protein transport; GO:0002682 regulation of immune system process; GO:0032736 positive regulation of interleukin-13 production; GO:0051023 regulation of immunoglobulin secretion; GO:0002821 positive regulation of adaptive immune response; GO:0051047 positive regulation of secretion; GO:0050794 regulation of cellular process; GO:0042127 regulation of cell proliferation; GO:0001819 positive regulation of cytokine production; GO:0002715 regulation of natural killer cell mediated immunity; GO:0048519 negative regulation of biological process; GO:0080134 regulation of response to stress; GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0051239 regulation of multicellular organismal process; GO:0050867 positive regulation of cell activation; GO:0031349 positive regulation of defense response; GO:0002475 antigen processing and presentation via MHC class Ib; GO:2000566 positive regulation of CD8-positive, alpha-beta T cell proliferation; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:0002707 negative regulation of lymphocyte mediated immunity; GO:0032880 regulation of protein localization; GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; GO:0071357 cellular response to type I interferon; GO:0046631 alpha-beta T cell activation; GO:0050778 positive regulation of immune response; GO:0009617 response to bacterium; GO:0036037 CD8-positive, alpha-beta T cell activation; GO:0032759 positive regulation of TRAIL production; GO:0045785 positive regulation of cell adhesion; GO:0006950 response to stress; GO:0031342 negative regulation of cell killing; GO:1903557 positive regulation of tumor necrosis factor superfamily cytokine production; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:1903039 positive regulation of leukocyte cell-cell adhesion; GO:0030155 regulation of cell adhesion; GO:0002696 positive regulation of leukocyte activation; GO:1904951 positive regulation of establishment of protein localization; GO:0002711 positive regulation of T cell mediated immunity; GO:0050870 positive regulation of T cell activation; GO:0001775 cell activation; GO:0042270 protection from natural killer cell mediated cytotoxicity; GO:0001911 negative regulation of leukocyte mediated cytotoxicity; GO:0048584 positive regulation of response to stimulus; GO:0006955 immune response; GO:0008284 positive regulation of cell proliferation; GO:0050863 regulation of T cell activation; GO:0002702 positive regulation of production of molecular mediator of immune response; GO:1903555 regulation of tumor necrosis factor superfamily cytokine production; GO:2000564 regulation of CD8-positive, alpha-beta T cell proliferation; GO:0071346 cellular response to interferon-gamma; GO:0051046 regulation of secretion; GO:0044699 single-organism process; GO:0002428 antigen processing and presentation of peptide antigen via MHC class Ib; GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib; GO:0051249 regulation of lymphocyte activation; GO:0032753 positive regulation of interleukin-4 production; GO:0046635 positive regulation of alpha-beta T cell activation; GO:0060333 interferon-gamma-mediated signaling pathway; GO:0007165 signal transduction; GO:0019883 antigen processing and presentation of endogenous antigen; GO:0050671 positive regulation of lymphocyte proliferation; GO:0007154 cell communication; GO:0045088 regulation of innate immune response; GO:0002250 adaptive immune response; GO:0002819 regulation of adaptive immune response; GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I; GO:0070663 regulation of leukocyte proliferation; GO:0050777 negative regulation of immune response; GO:2001185 regulation of CD8-positive, alpha-beta T cell activation; GO:0002697 regulation of immune effector process; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0070887 cellular response to chemical stimulus; GO:0002708 positive regulation of lymphocyte mediated immunity; GO:0019731 antibacterial humoral response; GO:0034097 response to cytokine; GO:0048002 antigen processing and presentation of peptide antigen; GO:0048522 positive regulation of cellular process; GO:0002700 regulation of production of molecular mediator of immune response; GO:0051024 positive regulation of immunoglobulin secretion; GO:0051251 positive regulation of lymphocyte activation; GO:0002716 negative regulation of natural killer cell mediated immunity; GO:1903530 regulation of secretion by cell; GO:0023052 signaling; GO:0050830 defense response to Gram-positive bacterium; GO:2001187 positive regulation of CD8-positive, alpha-beta T cell activation; GO:0051050 positive regulation of transport; GO:0002683 negative regulation of immune system process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0050865 regulation of cell activation; GO:1903532 positive regulation of secretion by cell; GO:0002705 positive regulation of leukocyte mediated immunity; GO:0042269 regulation of natural killer cell mediated cytotoxicity; GO:0006952 defense response; GO:0051222 positive regulation of protein transport; GO:0060337 type I interferon signaling pathway; GO:0042102 positive regulation of T cell proliferation; GO:0031341 regulation of cell killing; GO:0071310 cellular response to organic substance; GO:0002704 negative regulation of leukocyte mediated immunity; GO:0006959 humoral immune response; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0002706 regulation of lymphocyte mediated immunity; GO:0051707 response to other organism; GO:0070201 regulation of establishment of protein localization; GO:0045087 innate immune response; GO:0001912 positive regulation of leukocyte mediated cytotoxicity; GO:0045953 negative regulation of natural killer cell mediated cytotoxicity; GO:0001914 regulation of T cell mediated cytotoxicity; GO:0050708 regulation of protein secretion; GO:0001916 positive regulation of T cell mediated cytotoxicity; GO:0009987 cellular process; GO:0019221 cytokine-mediated signaling pathway; GO:0031348 negative regulation of defense response; GO:0046640 regulation of alpha-beta T cell proliferation; GO:0045089 positive regulation of innate immune response; GO:0001910 regulation of leukocyte mediated cytotoxicity; GO:0022409 positive regulation of cell-cell adhesion; GO:0042742 defense response to bacterium; GO:0051049 regulation of transport; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:0002699 positive regulation of immune effector process; GO:0046649 lymphocyte activation; GO:0042129 regulation of T cell proliferation; GO:0048585 negative regulation of response to stimulus; GO:0034341 response to interferon-gamma; GO:0048518 positive regulation of biological process; GO:0022407 regulation of cell-cell adhesion; GO:0045824 negative regulation of innate immune response; GO:0002703 regulation of leukocyte mediated immunity; GO:0019882 antigen processing and presentation; GO:0070665 positive regulation of leukocyte proliferation; GO:0002637 regulation of immunoglobulin production; GO:0002684 positive regulation of immune system process; GO:0001817 regulation of cytokine production; GO:0002483 antigen processing and presentation of endogenous peptide antigen; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0098552 side of membrane; GO:0010008 endosome membrane; GO:0030666 endocytic vesicle membrane; GO:0098797 plasma membrane protein complex; GO:0012506 vesicle membrane; GO:0044440 endosomal part; GO:0030135 coated vesicle; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0098553 lumenal side of endoplasmic reticulum membrane; GO:0042612 MHC class I protein complex; GO:0043234 protein complex; GO:0030133 transport vesicle; GO:0030176 integral component of endoplasmic reticulum membrane; GO:0043230 extracellular organelle; GO:0030658 transport vesicle membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0098796 membrane protein complex; GO:0071944 cell periphery; GO:0042611 MHC protein complex; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0055038 recycling endosome membrane; GO:0044424 intracellular part; GO:0030662 coated vesicle membrane; GO:0055037 recycling endosome; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0030670 phagocytic vesicle membrane; GO:1903561 extracellular vesicle; GO:0031227 intrinsic component of endoplasmic reticulum membrane; GO:0044431 Golgi apparatus part; GO:0005768 endosome; GO:0031901 early endosome membrane; GO:0030139 endocytic vesicle; GO:0012507 ER to Golgi transport vesicle membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0045335 phagocytic vesicle; GO:0030134 ER to Golgi transport vesicle; GO:0016021 integral component of membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0044432 endoplasmic reticulum part; GO:0032398 MHC class Ib protein complex; GO:0009986 cell surface; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:0030881 beta-2-microglobulin binding; GO:0042277 peptide binding; GO:0005102 receptor binding; GO:0005488 binding; GO:0046703 natural killer cell lectin-like receptor binding; GO:0042287 MHC protein binding; GO:0005515 protein binding; GO:0033218 amide binding; GO:0042605 peptide antigen binding; GO:0042288 MHC class I protein binding; GO:0003823 antigen binding; ","K06751","MHC1; major histocompatibility complex, class I","hsa05330 Allograft rejection - Homo sapiens (human); hsa04650 Natural killer cell mediated cytotoxicity - Homo sapiens (human); hsa04218 Cellular senescence - Homo sapiens (human); hsa05168 Herpes simplex infection - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa05416 Viral myocarditis - Homo sapiens (human); hsa05167 Kaposi's sarcoma-associated herpesvirus infection - Homo sapiens (human); hsa05203 Viral carcinogenesis - Homo sapiens (human); hsa05166 HTLV-I infection - Homo sapiens (human); hsa04144 Endocytosis - Homo sapiens (human); hsa04612 Antigen processing and presentation - Homo sapiens (human); hsa04940 Type I diabetes mellitus - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); hsa04514 Cell adhesion molecules (CAMs) - Homo sapiens (human); hsa05332 Graft-versus-host disease - Homo sapiens (human); hsa05320 Autoimmune thyroid disease - Homo sapiens (human); ","IPR007110; IPR013783; IPR010579; IPR011161; IPR011162; IPR001039; IPR003597; ","\"Immunoglobulin-like domain; Immunoglobulin-like fold; MHC class I, alpha chain, C-terminal; MHC class I-like antigen recognition-like; MHC classes I/II-like antigen recognition protein; MHC class I alpha chain, alpha1 alpha2 domains; Immunoglobulin C1-set; \"\r"]
["P13761","HLA class II histocompatibility antigen, DRB1-7 beta chain OS=Homo sapiens OX=9606 GN=HLA-DRB1","HLA-DRB1",29.822,2.8923,21.4,5,6,2,0.378,0.428,0.487,1.574,1.45,1.617,3.589,8.46e-05,"extracellular\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0002694 regulation of leukocyte activation; GO:0050672 negative regulation of lymphocyte proliferation; GO:0016064 immunoglobulin mediated immune response; GO:0065008 regulation of biological quality; GO:0032944 regulation of mononuclear cell proliferation; GO:0007166 cell surface receptor signaling pathway; GO:0050796 regulation of insulin secretion; GO:0002793 positive regulation of peptide secretion; GO:0071345 cellular response to cytokine stimulus; GO:0009607 response to biotic stimulus; GO:0008285 negative regulation of cell proliferation; GO:0009605 response to external stimulus; GO:0032673 regulation of interleukin-4 production; GO:0070664 negative regulation of leukocyte proliferation; GO:0065003 macromolecular complex assembly; GO:0032879 regulation of localization; GO:0051606 detection of stimulus; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:1903038 negative regulation of leukocyte cell-cell adhesion; GO:0016045 detection of bacterium; GO:0050707 regulation of cytokine secretion; GO:0050670 regulation of lymphocyte proliferation; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0046883 regulation of hormone secretion; GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; GO:0048583 regulation of response to stimulus; GO:0002381 immunoglobulin production involved in immunoglobulin mediated immune response; GO:0050714 positive regulation of protein secretion; GO:0010817 regulation of hormone levels; GO:0002682 regulation of immune system process; GO:0051223 regulation of protein transport; GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II; GO:0051047 positive regulation of secretion; GO:0050794 regulation of cellular process; GO:0007162 negative regulation of cell adhesion; GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus; GO:0042127 regulation of cell proliferation; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0022408 negative regulation of cell-cell adhesion; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0032844 regulation of homeostatic process; GO:0051239 regulation of multicellular organismal process; GO:0090277 positive regulation of peptide hormone secretion; GO:0019724 B cell mediated immunity; GO:0051259 protein oligomerization; GO:0060341 regulation of cellular localization; GO:0050866 negative regulation of cell activation; GO:0050867 positive regulation of cell activation; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:0032880 regulation of protein localization; GO:0002449 lymphocyte mediated immunity; GO:0050778 positive regulation of immune response; GO:0009617 response to bacterium; GO:0006461 protein complex assembly; GO:0002253 activation of immune response; GO:0090087 regulation of peptide transport; GO:0045785 positive regulation of cell adhesion; GO:0006950 response to stress; GO:0009595 detection of biotic stimulus; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:1903039 positive regulation of leukocyte cell-cell adhesion; GO:0030155 regulation of cell adhesion; GO:0002696 positive regulation of leukocyte activation; GO:2001179 regulation of interleukin-10 secretion; GO:1904951 positive regulation of establishment of protein localization; GO:0050870 positive regulation of T cell activation; GO:0046887 positive regulation of hormone secretion; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0006955 immune response; GO:0048584 positive regulation of response to stimulus; GO:0032689 negative regulation of interferon-gamma production; GO:0050863 regulation of T cell activation; GO:0023051 regulation of signaling; GO:0071346 cellular response to interferon-gamma; GO:0051241 negative regulation of multicellular organismal process; GO:0051046 regulation of secretion; GO:0042130 negative regulation of T cell proliferation; GO:0044699 single-organism process; GO:0031294 lymphocyte costimulation; GO:0098581 detection of external biotic stimulus; GO:0001818 negative regulation of cytokine production; GO:0051249 regulation of lymphocyte activation; GO:0060333 interferon-gamma-mediated signaling pathway; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0051262 protein tetramerization; GO:0002250 adaptive immune response; GO:0032846 positive regulation of homeostatic process; GO:0070663 regulation of leukocyte proliferation; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0002695 negative regulation of leukocyte activation; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0070887 cellular response to chemical stimulus; GO:0050851 antigen receptor-mediated signaling pathway; GO:0002437 inflammatory response to antigenic stimulus; GO:0071822 protein complex subunit organization; GO:0034097 response to cytokine; GO:0048002 antigen processing and presentation of peptide antigen; GO:0048522 positive regulation of cellular process; GO:0051251 positive regulation of lymphocyte activation; GO:0002764 immune response-regulating signaling pathway; GO:1903530 regulation of secretion by cell; GO:0023052 signaling; GO:0002495 antigen processing and presentation of peptide antigen via MHC class II; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0051050 positive regulation of transport; GO:0002683 negative regulation of immune system process; GO:0050789 regulation of biological process; GO:0050865 regulation of cell activation; GO:0042221 response to chemical; GO:0002440 production of molecular mediator of immune response; GO:1903532 positive regulation of secretion by cell; GO:0006954 inflammatory response; GO:0006952 defense response; GO:0070271 protein complex biogenesis; GO:0050868 negative regulation of T cell activation; GO:0051222 positive regulation of protein transport; GO:0016043 cellular component organization; GO:0051250 negative regulation of lymphocyte activation; GO:0002252 immune effector process; GO:0071310 cellular response to organic substance; GO:0006959 humoral immune response; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0070201 regulation of establishment of protein localization; GO:0045087 innate immune response; GO:0002791 regulation of peptide secretion; GO:0023056 positive regulation of signaling; GO:0002757 immune response-activating signal transduction; GO:0010647 positive regulation of cell communication; GO:0050708 regulation of protein secretion; GO:0019221 cytokine-mediated signaling pathway; GO:0009987 cellular process; GO:0032649 regulation of interferon-gamma production; GO:0032024 positive regulation of insulin secretion; GO:0022409 positive regulation of cell-cell adhesion; GO:0051049 regulation of transport; GO:0031295 T cell costimulation; GO:0042129 regulation of T cell proliferation; GO:0032945 negative regulation of mononuclear cell proliferation; GO:0042088 T-helper 1 type immune response; GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus; GO:0034341 response to interferon-gamma; GO:0048518 positive regulation of biological process; GO:0022407 regulation of cell-cell adhesion; GO:0043933 macromolecular complex subunit organization; GO:0032653 regulation of interleukin-10 production; GO:0019882 antigen processing and presentation; GO:0098543 detection of other organism; GO:0050852 T cell receptor signaling pathway; GO:0002377 immunoglobulin production; GO:0002684 positive regulation of immune system process; GO:0090276 regulation of peptide hormone secretion; GO:0001817 regulation of cytokine production; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0009897 external side of plasma membrane; GO:0045334 clathrin-coated endocytic vesicle; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0032588 trans-Golgi network membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0005765 lysosomal membrane; GO:0042613 MHC class II protein complex; GO:0030136 clathrin-coated vesicle; GO:0031902 late endosome membrane; GO:0005622 intracellular; GO:0005764 lysosome; GO:0098791 Golgi subcompartment; GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0000323 lytic vacuole; GO:0098552 side of membrane; GO:0010008 endosome membrane; GO:0005770 late endosome; GO:0030666 endocytic vesicle membrane; GO:0098797 plasma membrane protein complex; GO:0044440 endosomal part; GO:0012506 vesicle membrane; GO:0030135 coated vesicle; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0098553 lumenal side of endoplasmic reticulum membrane; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0030176 integral component of endoplasmic reticulum membrane; GO:0043234 protein complex; GO:0030133 transport vesicle; GO:0030658 transport vesicle membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0042611 MHC protein complex; GO:0030669 clathrin-coated endocytic vesicle membrane; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0030662 coated vesicle membrane; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0031227 intrinsic component of endoplasmic reticulum membrane; GO:0044431 Golgi apparatus part; GO:0005768 endosome; GO:0030139 endocytic vesicle; GO:0012507 ER to Golgi transport vesicle membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0030134 ER to Golgi transport vesicle; GO:0012505 endomembrane system; GO:0016021 integral component of membrane; GO:0030665 clathrin-coated vesicle membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0044432 endoplasmic reticulum part; GO:0005802 trans-Golgi network; GO:0005774 vacuolar membrane; GO:0009986 cell surface; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; GO:0031984 organelle subcompartment; ","GO:0038023 signaling receptor activity; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0042277 peptide binding; GO:0005488 binding; GO:0005515 protein binding; GO:0042605 peptide antigen binding; GO:0033218 amide binding; GO:0004888 transmembrane signaling receptor activity; GO:0004871 signal transducer activity; GO:0032395 MHC class II receptor activity; GO:0003823 antigen binding; GO:0099600 transmembrane receptor activity; ",{"$nulls":3},"IPR007110; IPR014745; IPR013783; IPR011162; IPR000353; IPR003597; ","\"Immunoglobulin-like domain; MHC class II, alpha/beta chain, N-terminal; Immunoglobulin-like fold; MHC classes I/II-like antigen recognition protein; MHC class II, beta chain, N-terminal; Immunoglobulin C1-set; \"\r"]
["P13796","Plastin-2 OS=Homo sapiens OX=9606 GN=LCP1","LCP1",70.288,247.19,55.7,30,80,23,0.861,0.861,0.884,1.158,1.131,1.084,1.294,0.000262,"cytoplasm\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0031100 animal organ regeneration; GO:0045321 leukocyte activation; GO:0051674 localization of cell; GO:0044699 single-organism process; GO:1902115 regulation of organelle assembly; GO:0051130 positive regulation of cellular component organization; GO:0042110 T cell activation; GO:0007165 signal transduction; GO:0030036 actin cytoskeleton organization; GO:0071801 regulation of podosome assembly; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0032879 regulation of localization; GO:0022617 extracellular matrix disassembly; GO:0031334 positive regulation of protein complex assembly; GO:0030198 extracellular matrix organization; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0071803 positive regulation of podosome assembly; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0032386 regulation of intracellular transport; GO:0048870 cell motility; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:1902589 single-organism organelle organization; GO:0048513 animal organ development; GO:0043254 regulation of protein complex assembly; GO:0050789 regulation of biological process; GO:0010638 positive regulation of organelle organization; GO:1902117 positive regulation of organelle assembly; GO:0051223 regulation of protein transport; GO:0040011 locomotion; GO:0048856 anatomical structure development; GO:0097435 supramolecular fiber organization; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0016477 cell migration; GO:0016043 cellular component organization; GO:0002252 immune effector process; GO:0007015 actin filament organization; GO:0044087 regulation of cellular component biogenesis; GO:0051017 actin filament bundle assembly; GO:0002286 T cell activation involved in immune response; GO:0050896 response to stimulus; GO:0070201 regulation of establishment of protein localization; GO:0060341 regulation of cellular localization; GO:0010737 protein kinase A signaling; GO:0043062 extracellular structure organization; GO:0007275 multicellular organism development; GO:0032880 regulation of protein localization; GO:0007010 cytoskeleton organization; GO:0033157 regulation of intracellular protein transport; GO:0009987 cellular process; GO:0051764 actin crosslink formation; GO:0002285 lymphocyte activation involved in immune response; GO:0035556 intracellular signal transduction; GO:0048731 system development; GO:0051049 regulation of transport; GO:0033043 regulation of organelle organization; GO:0046649 lymphocyte activation; GO:0002376 immune system process; GO:0048518 positive regulation of biological process; GO:0002263 cell activation involved in immune response; GO:0061572 actin filament bundle organization; GO:0002366 leukocyte activation involved in immune response; GO:0051639 actin filament network formation; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0030029 actin filament-based process; GO:0006928 movement of cell or subcellular component; GO:0001775 cell activation; GO:0022411 cellular component disassembly; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0031099 regeneration; GO:0006955 immune response; GO:0044089 positive regulation of cellular component biogenesis; GO:1903827 regulation of cellular protein localization; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0032587 ruffle membrane; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0098858 actin-based cell projection; GO:0005623 cell; GO:0044422 organelle part; GO:0032432 actin filament bundle; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005856 cytoskeleton; GO:0005925 focal adhesion; GO:0098590 plasma membrane region; GO:0031256 leading edge membrane; GO:0005622 intracellular; GO:0044425 membrane part; GO:0044464 cell part; GO:0001891 phagocytic cup; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030175 filopodium; GO:0005884 actin filament; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0031252 cell leading edge; GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0005829 cytosol; GO:0002102 podosome; GO:0044463 cell projection part; GO:0005576 extracellular region; GO:0015629 actin cytoskeleton; GO:0099081 supramolecular polymer; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0031253 cell projection membrane; GO:0001726 ruffle; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0051015 actin filament binding; GO:0042802 identical protein binding; GO:0008092 cytoskeletal protein binding; GO:0005488 binding; GO:0043167 ion binding; GO:0044877 macromolecular complex binding; GO:0003779 actin binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0005509 calcium ion binding; GO:0051020 GTPase binding; GO:0019899 enzyme binding; GO:0032403 protein complex binding; ","K17276",null,null,"IPR002048; IPR001715; IPR011992; ","EF-hand domain; Calponin homology domain; EF-hand domain pair; \r"]
["P13797","Plastin-3 OS=Homo sapiens OX=9606 GN=PLS3","PLS3",70.81,152.24,45.6,27,66,20,0.995,0.994,0.964,1.04,1.026,1.014,1.043,0.0294,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0032502 developmental process; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0051764 actin crosslink formation; GO:0048731 system development; GO:0044763 single-organism cellular process; GO:0007015 actin filament organization; GO:0044699 single-organism process; GO:0051017 actin filament bundle assembly; GO:0032501 multicellular organismal process; GO:0061572 actin filament bundle organization; GO:0060348 bone development; GO:1902589 single-organism organelle organization; GO:0051639 actin filament network formation; GO:0048513 animal organ development; GO:0030036 actin cytoskeleton organization; GO:0022607 cellular component assembly; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0030029 actin filament-based process; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0097435 supramolecular fiber organization; GO:0009987 cellular process; GO:0048856 anatomical structure development; GO:0001501 skeletal system development; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0043232 intracellular non-membrane-bounded organelle; GO:0071944 cell periphery; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0015629 actin cytoskeleton; GO:0032432 actin filament bundle; GO:0044422 organelle part; GO:0005886 plasma membrane; GO:0099081 supramolecular polymer; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0043226 organelle; GO:0005622 intracellular; GO:0044464 cell part; GO:0005884 actin filament; GO:0044444 cytoplasmic part; ","GO:0051015 actin filament binding; GO:0008092 cytoskeletal protein binding; GO:0005488 binding; GO:0043167 ion binding; GO:0044877 macromolecular complex binding; GO:0003779 actin binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0005509 calcium ion binding; GO:0032403 protein complex binding; ","K17336",null,null,"IPR002048; IPR011992; IPR001715; ","EF-hand domain; EF-hand domain pair; Calponin homology domain; \r"]
["P13798","Acylamino-acid-releasing enzyme OS=Homo sapiens OX=9606 GN=APEH","APEH",81.224,44.467,12.3,9,14,9,0.925,0.92,0.942,1.027,1.026,1.093,1.129,0.00546,"cytoplasm\r","GO:0045321 leukocyte activation; GO:0006518 peptide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0043241 protein complex disassembly; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006412 translation; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0002443 leukocyte mediated immunity; GO:0071822 protein complex subunit organization; GO:0043043 peptide biosynthetic process; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0043603 cellular amide metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0006810 transport; GO:0006415 translational termination; GO:0032940 secretion by cell; GO:0044260 cellular macromolecule metabolic process; GO:0043299 leukocyte degranulation; GO:0016043 cellular component organization; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0044267 cellular protein metabolic process; GO:0050435 beta-amyloid metabolic process; GO:0050896 response to stimulus; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0043624 cellular protein complex disassembly; GO:0006508 proteolysis; GO:0034641 cellular nitrogen compound metabolic process; GO:0036230 granulocyte activation; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0016192 vesicle-mediated transport; GO:0006807 nitrogen compound metabolic process; GO:0032984 macromolecular complex disassembly; GO:0002376 immune system process; GO:0043312 neutrophil degranulation; GO:0044238 primary metabolic process; GO:0002263 cell activation involved in immune response; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0001775 cell activation; GO:0022411 cellular component disassembly; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0006955 immune response; GO:0051179 localization; GO:0071840 cellular component organization or biogenesis; GO:1901564 organonitrogen compound metabolic process; GO:0006887 exocytosis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0101002 ficolin-1-rich granule; GO:0031965 nuclear membrane; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0005635 nuclear envelope; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0031975 envelope; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0003723 RNA binding; GO:0008238 exopeptidase activity; GO:0008233 peptidase activity; GO:0008236 serine-type peptidase activity; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0004175 endopeptidase activity; GO:0004252 serine-type endopeptidase activity; GO:0042802 identical protein binding; GO:0017171 serine hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0008242 omega peptidase activity; ","K01303",null,null,"IPR001375; IPR029058; IPR011042; ","\"Peptidase S9, prolyl oligopeptidase, catalytic domain; Alpha/Beta hydrolase fold; Six-bladed beta-propeller, TolB-like; \"\r"]
["P13804","Electron transfer flavoprotein subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ETFA","ETFA",35.079,98.491,39.6,10,18,10,1.114,1.057,1.093,0.919,0.947,0.907,0.85,0.00122,"mitochondria\r","GO:0034440 lipid oxidation; GO:0044699 single-organism process; GO:0022904 respiratory electron transport chain; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0030258 lipid modification; GO:0044248 cellular catabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0009987 cellular process; GO:0006629 lipid metabolic process; GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase; GO:0016042 lipid catabolic process; GO:0019395 fatty acid oxidation; GO:0055114 oxidation-reduction process; GO:0044712 single-organism catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006635 fatty acid beta-oxidation; GO:0072329 monocarboxylic acid catabolic process; GO:0044282 small molecule catabolic process; GO:0006631 fatty acid metabolic process; GO:0044238 primary metabolic process; GO:0045333 cellular respiration; GO:0046395 carboxylic acid catabolic process; GO:1901575 organic substance catabolic process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0019752 carboxylic acid metabolic process; GO:0016054 organic acid catabolic process; GO:0022900 electron transport chain; GO:0044242 cellular lipid catabolic process; GO:0006082 organic acid metabolic process; GO:0009056 catabolic process; GO:0009062 fatty acid catabolic process; GO:0043436 oxoacid metabolic process; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:1901265 nucleoside phosphate binding; GO:0050660 flavin adenine dinucleotide binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0048037 cofactor binding; GO:0016491 oxidoreductase activity; GO:0009055 electron carrier activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043168 anion binding; GO:0050662 coenzyme binding; GO:0036094 small molecule binding; ","K03522",null,null,"IPR014731; IPR014729; IPR033947; IPR014730; IPR029035; ","\"Electron transfer flavoprotein, alpha subunit, C-terminal; Rossmann-like alpha/beta/alpha sandwich fold; Electron transfer flavoprotein, alpha subunit, N-terminal; Electron transfer flavoprotein, alpha/beta-subunit, N-terminal; DHS-like NAD/FAD-binding domain; \"\r"]
["P13807","Glycogen [starch] synthase, muscle OS=Homo sapiens OX=9606 GN=GYS1","GYS1",83.785,7.4415,4.3,3,3,3,1.01,1.007,0.996,1.019,1.013,0.966,0.995,0.778,"nucleus\r","GO:0072359 circulatory system development; GO:0044707 single-multicellular organism process; GO:0016051 carbohydrate biosynthetic process; GO:0000271 polysaccharide biosynthetic process; GO:0044042 glucan metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0006112 energy reserve metabolic process; GO:0044237 cellular metabolic process; GO:0044264 cellular polysaccharide metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0007507 heart development; GO:0006091 generation of precursor metabolites and energy; GO:0044262 cellular carbohydrate metabolic process; GO:0005976 polysaccharide metabolic process; GO:0005978 glycogen biosynthetic process; GO:0043170 macromolecule metabolic process; GO:0007275 multicellular organism development; GO:0009059 macromolecule biosynthetic process; GO:0034637 cellular carbohydrate biosynthetic process; GO:0009987 cellular process; GO:0032502 developmental process; GO:0044711 single-organism biosynthetic process; GO:0006073 cellular glucan metabolic process; GO:0048731 system development; GO:0055114 oxidation-reduction process; GO:0044763 single-organism cellular process; GO:0005977 glycogen metabolic process; GO:0033692 cellular polysaccharide biosynthetic process; GO:0044238 primary metabolic process; GO:0005975 carbohydrate metabolic process; GO:1901576 organic substance biosynthetic process; GO:0032501 multicellular organismal process; GO:0044249 cellular biosynthetic process; GO:0009250 glucan biosynthetic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0048513 animal organ development; GO:0034645 cellular macromolecule biosynthetic process; GO:0044767 single-organism developmental process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0044260 cellular macromolecule metabolic process; GO:0048856 anatomical structure development; ","GO:0016020 membrane; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0016234 inclusion body; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:0016758 transferase activity, transferring hexosyl groups; GO:0005536 glucose binding; GO:0019901 protein kinase binding; GO:0046527 glucosyltransferase activity; GO:0008194 UDP-glycosyltransferase activity; GO:0004373 glycogen (starch) synthase activity; GO:0005515 protein binding; GO:0048029 monosaccharide binding; GO:0019900 kinase binding; GO:0061547 glycogen synthase activity, transferring glucose-1-phosphate; GO:0003824 catalytic activity; GO:0005488 binding; GO:0035251 UDP-glucosyltransferase activity; GO:0030246 carbohydrate binding; GO:0016757 transferase activity, transferring glycosyl groups; GO:0016740 transferase activity; GO:0019899 enzyme binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0036094 small molecule binding; ","K00693","GYS; glycogen synthase [EC:2.4.1.11]","hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00500 Starch and sucrose metabolism - Homo sapiens (human); hsa04922 Glucagon signaling pathway - Homo sapiens (human); hsa04910 Insulin signaling pathway - Homo sapiens (human); hsa04931 Insulin resistance - Homo sapiens (human); hsa04152 AMPK signaling pathway - Homo sapiens (human); "]
["P13861","cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2A","PRKAR2A",45.518,87.936,44.3,16,22,14,1.035,1.054,1.047,0.966,0.944,0.983,0.923,3.3E-3,"cytoplasm\r","GO:0044700 single organism signaling; GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0044699 single-organism process; GO:0048871 multicellular organismal homeostasis; GO:0031400 negative regulation of protein modification process; GO:0009611 response to wounding; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0007165 signal transduction; GO:1901653 cellular response to peptide; GO:0071901 negative regulation of protein serine/threonine kinase activity; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0033673 negative regulation of kinase activity; GO:0044093 positive regulation of molecular function; GO:0009719 response to endogenous stimulus; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0051347 positive regulation of transferase activity; GO:0033674 positive regulation of kinase activity; GO:1901652 response to peptide; GO:0070887 cellular response to chemical stimulus; GO:0003091 renal water homeostasis; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0045937 positive regulation of phosphate metabolic process; GO:0080090 regulation of primary metabolic process; GO:0048522 positive regulation of cellular process; GO:0051348 negative regulation of transferase activity; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0032501 multicellular organismal process; GO:0071417 cellular response to organonitrogen compound; GO:2000480 negative regulation of cAMP-dependent protein kinase activity; GO:0010243 response to organonitrogen compound; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0030104 water homeostasis; GO:0043434 response to peptide hormone; GO:1901699 cellular response to nitrogen compound; GO:0032870 cellular response to hormone stimulus; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:1901698 response to nitrogen compound; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006469 negative regulation of protein kinase activity; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0050817 coagulation; GO:0019220 regulation of phosphate metabolic process; GO:0043549 regulation of kinase activity; GO:0050794 regulation of cellular process; GO:0045859 regulation of protein kinase activity; GO:0044707 single-multicellular organism process; GO:0060255 regulation of macromolecule metabolic process; GO:0031399 regulation of protein modification process; GO:0071310 cellular response to organic substance; GO:1901700 response to oxygen-containing compound; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0007599 hemostasis; GO:0042592 homeostatic process; GO:0071377 cellular response to glucagon stimulus; GO:0032147 activation of protein kinase activity; GO:0042326 negative regulation of phosphorylation; GO:0071375 cellular response to peptide hormone stimulus; GO:0051338 regulation of transferase activity; GO:0001933 negative regulation of protein phosphorylation; GO:0034199 activation of protein kinase A activity; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0003008 system process; GO:0050878 regulation of body fluid levels; GO:0006950 response to stress; GO:0035556 intracellular signal transduction; GO:0003014 renal system process; GO:0001932 regulation of protein phosphorylation; GO:0031401 positive regulation of protein modification process; GO:0010033 response to organic substance; GO:0045860 positive regulation of protein kinase activity; GO:0001934 positive regulation of protein phosphorylation; GO:0048518 positive regulation of biological process; GO:0009892 negative regulation of metabolic process; GO:0043085 positive regulation of catalytic activity; GO:0051247 positive regulation of protein metabolic process; GO:1901701 cellular response to oxygen-containing compound; GO:0042060 wound healing; GO:2000479 regulation of cAMP-dependent protein kinase activity; GO:0050891 multicellular organismal water homeostasis; GO:0071495 cellular response to endogenous stimulus; GO:0051246 regulation of protein metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0010563 negative regulation of phosphorus metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0033762 response to glucagon; GO:0009725 response to hormone; GO:0045936 negative regulation of phosphate metabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0061695 transferase complex, transferring phosphorus-containing groups; GO:0098857 membrane microdomain; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:1902911 protein kinase complex; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0005815 microtubule organizing center; GO:1902494 catalytic complex; GO:0098590 plasma membrane region; GO:0005925 focal adhesion; GO:0044441 ciliary part; GO:0015630 microtubule cytoskeleton; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0098589 membrane region; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030055 cell-substrate junction; GO:0045121 membrane raft; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0097546 ciliary base; GO:0005929 cilium; GO:0043229 intracellular organelle; GO:0031588 nucleotide-activated protein kinase complex; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:1990234 transferase complex; GO:0044463 cell projection part; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0005952 cAMP-dependent protein kinase complex; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0005813 centrosome; GO:0044853 plasma membrane raft; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0030291 protein serine/threonine kinase inhibitor activity; GO:0051018 protein kinase A binding; GO:1901265 nucleoside phosphate binding; GO:0031625 ubiquitin protein ligase binding; GO:0019901 protein kinase binding; GO:0004860 protein kinase inhibitor activity; GO:0005515 protein binding; GO:0019207 kinase regulator activity; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0043168 anion binding; GO:0008603 cAMP-dependent protein kinase regulator activity; GO:0004862 cAMP-dependent protein kinase inhibitor activity; GO:0030554 adenyl nucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0017076 purine nucleotide binding; GO:0030552 cAMP binding; GO:0030551 cyclic nucleotide binding; GO:0043167 ion binding; GO:0000166 nucleotide binding; GO:0019887 protein kinase regulator activity; GO:0019900 kinase binding; GO:0097367 carbohydrate derivative binding; GO:0030234 enzyme regulator activity; GO:0019210 kinase inhibitor activity; GO:0032555 purine ribonucleotide binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0034236 protein kinase A catalytic subunit binding; GO:0019899 enzyme binding; GO:0036094 small molecule binding; ","K04739","PRKAR; cAMP-dependent protein kinase regulator","hsa04910 Insulin signaling pathway - Homo sapiens (human); ","IPR000595; IPR018490; IPR003117; IPR014710; ","\"Cyclic nucleotide-binding domain; Cyclic nucleotide-binding-like; cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain; RmlC-like jelly roll fold; \"\r"]
["P13928","Annexin A8 OS=Homo sapiens OX=9606 GN=ANXA8","ANXA8",36.881,73.184,29.7,10,17,1,0.924,0.853,0.77,1.117,1.152,1.175,1.352,0.00514,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0010256 endomembrane system organization; GO:0010951 negative regulation of endopeptidase activity; GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0060255 regulation of macromolecule metabolic process; GO:0010517 regulation of phospholipase activity; GO:0044699 single-organism process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:0032429 regulation of phospholipase A2 activity; GO:0051346 negative regulation of hydrolase activity; GO:0007599 hemostasis; GO:0051234 establishment of localization; GO:0009611 response to wounding; GO:0010466 negative regulation of peptidase activity; GO:0009987 cellular process; GO:0052548 regulation of endopeptidase activity; GO:0060192 negative regulation of lipase activity; GO:0045861 negative regulation of proteolysis; GO:0050878 regulation of body fluid levels; GO:0006950 response to stress; GO:0080090 regulation of primary metabolic process; GO:1900003 regulation of serine-type endopeptidase activity; GO:0060191 regulation of lipase activity; GO:1900138 negative regulation of phospholipase A2 activity; GO:0016050 vesicle organization; GO:1902572 negative regulation of serine-type peptidase activity; GO:0030162 regulation of proteolysis; GO:0031323 regulation of cellular metabolic process; GO:0043086 negative regulation of catalytic activity; GO:1902571 regulation of serine-type peptidase activity; GO:0010605 negative regulation of macromolecule metabolic process; GO:0009892 negative regulation of metabolic process; GO:0032501 multicellular organismal process; GO:0016197 endosomal transport; GO:0006810 transport; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0042060 wound healing; GO:0051336 regulation of hydrolase activity; GO:0006996 organelle organization; GO:0051246 regulation of protein metabolic process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0051248 negative regulation of protein metabolic process; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:1900004 negative regulation of serine-type endopeptidase activity; GO:0044092 negative regulation of molecular function; GO:0050817 coagulation; GO:0052547 regulation of peptidase activity; GO:0051179 localization; GO:0007032 endosome organization; GO:0010519 negative regulation of phospholipase activity; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0010008 endosome membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0016020 membrane; GO:0098588 bounding membrane of organelle; GO:0005770 late endosome; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044440 endosomal part; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0005622 intracellular; GO:0044464 cell part; GO:0031902 late endosome membrane; GO:0098805 whole membrane; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0051015 actin filament binding; GO:1901981 phosphatidylinositol phosphate binding; GO:0005544 calcium-dependent phospholipid binding; GO:0043167 ion binding; GO:0044877 macromolecular complex binding; GO:0005515 protein binding; GO:0043325 phosphatidylinositol-3,4-bisphosphate binding; GO:1902936 phosphatidylinositol bisphosphate binding; GO:0008092 cytoskeletal protein binding; GO:0005488 binding; GO:0005546 phosphatidylinositol-4,5-bisphosphate binding; GO:0005543 phospholipid binding; GO:0035091 phosphatidylinositol binding; GO:0003779 actin binding; GO:0008289 lipid binding; GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0005509 calcium ion binding; GO:0032403 protein complex binding; ","K17096"]
["P13984","General transcription factor IIF subunit 2 OS=Homo sapiens OX=9606 GN=GTF2F2","GTF2F2",28.38,9.7872,15.7,4,4,4,0.949,1.004,0.926,1.123,0.946,1.059,1.086,0.22,"cytoplasm\r","GO:0060260 regulation of transcription initiation from RNA polymerase II promoter; GO:0044700 single organism signaling; GO:0007166 cell surface receptor signaling pathway; GO:0097659 nucleic acid-templated transcription; GO:0009891 positive regulation of biosynthetic process; GO:0006354 DNA-templated transcription, elongation; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0032784 regulation of DNA-templated transcription, elongation; GO:0009719 response to endogenous stimulus; GO:0070848 response to growth factor; GO:0043170 macromolecule metabolic process; GO:0006396 RNA processing; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0032786 positive regulation of DNA-templated transcription, elongation; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050434 positive regulation of viral transcription; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0098781 ncRNA transcription; GO:0009889 regulation of biosynthetic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0071774 response to fibroblast growth factor; GO:0016073 snRNA metabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0008380 RNA splicing; GO:0051254 positive regulation of RNA metabolic process; GO:0006370 7-methylguanosine mRNA capping; GO:2000142 regulation of DNA-templated transcription, initiation; GO:0043900 regulation of multi-organism process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006368 transcription elongation from RNA polymerase II promoter; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter; GO:0034243 regulation of transcription elongation from RNA polymerase II promoter; GO:0046782 regulation of viral transcription; GO:0031325 positive regulation of cellular metabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0042795 snRNA transcription from RNA polymerase II promoter; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0071363 cellular response to growth factor stimulus; GO:0008543 fibroblast growth factor receptor signaling pathway; GO:0051130 positive regulation of cellular component organization; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:2000144 positive regulation of DNA-templated transcription, initiation; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0031334 positive regulation of protein complex assembly; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0070887 cellular response to chemical stimulus; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0010468 regulation of gene expression; GO:1903902 positive regulation of viral life cycle; GO:0036260 RNA capping; GO:0043902 positive regulation of multi-organism process; GO:0031326 regulation of cellular biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:0009301 snRNA transcription; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0043254 regulation of protein complex assembly; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0019222 regulation of metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0071310 cellular response to organic substance; GO:0006352 DNA-templated transcription, initiation; GO:0044087 regulation of cellular component biogenesis; GO:0009452 7-methylguanosine RNA capping; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006367 transcription initiation from RNA polymerase II promoter; GO:0006355 regulation of transcription, DNA-templated; GO:0050792 regulation of viral process; GO:0006807 nitrogen compound metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0048524 positive regulation of viral process; GO:0071495 cellular response to endogenous stimulus; GO:0006366 transcription from RNA polymerase II promoter; GO:0044344 cellular response to fibroblast growth factor stimulus; GO:0010467 gene expression; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0051128 regulation of cellular component organization; GO:1903900 regulation of viral life cycle; GO:0034660 ncRNA metabolic process; GO:0044089 positive regulation of cellular component biogenesis; GO:0065007 biological regulation; ","GO:0061695 transferase complex, transferring phosphorus-containing groups; GO:0005674 transcription factor TFIIF complex; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0055029 nuclear DNA-directed RNA polymerase complex; GO:0000428 DNA-directed RNA polymerase complex; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0030880 RNA polymerase complex; GO:0031981 nuclear lumen; GO:1990234 transferase complex; GO:0044798 nuclear transcription factor complex; GO:0005667 transcription factor complex; GO:0016591 DNA-directed RNA polymerase II, holoenzyme; GO:0090575 RNA polymerase II transcription factor complex; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0043234 protein complex; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003677 DNA binding; GO:0005524 ATP binding; GO:0004386 helicase activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0000991 transcription factor activity, core RNA polymerase II binding; GO:0097367 carbohydrate derivative binding; GO:0003676 nucleic acid binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0000988 transcription factor activity, protein binding; GO:0000990 transcription factor activity, core RNA polymerase binding; GO:0036094 small molecule binding; ","K03139","TFIIF2; transcription initiation factor TFIIF subunit beta [EC:3.6.4.12]","hsa03022 Basal transcription factors - Homo sapiens (human); ","IPR011991; IPR011039; ","\"Winged helix-turn-helix DNA-binding domain; Transcription Factor IIF, Rap30/Rap74, interaction; \"\r"]
["P13987","CD59 glycoprotein OS=Homo sapiens OX=9606 GN=CD59","CD59",14.177,32.61,25.8,6,10,6,1.229,1.102,1.127,0.86,0.89,0.892,0.764,0.0016,"extracellular\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0002694 regulation of leukocyte activation; GO:0010941 regulation of cell death; GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0032944 regulation of mononuclear cell proliferation; GO:0048208 COPII vesicle coating; GO:0007166 cell surface receptor signaling pathway; GO:0002698 negative regulation of immune effector process; GO:1903318 negative regulation of protein maturation; GO:0045916 negative regulation of complement activation; GO:0031347 regulation of defense response; GO:0032946 positive regulation of mononuclear cell proliferation; GO:0065003 macromolecular complex assembly; GO:0048199 vesicle targeting, to, from or within Golgi; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0050670 regulation of lymphocyte proliferation; GO:0031323 regulation of cellular metabolic process; GO:0001969 regulation of activation of membrane attack complex; GO:0032501 multicellular organismal process; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0032269 negative regulation of cellular protein metabolic process; GO:0048583 regulation of response to stimulus; GO:0002682 regulation of immune system process; GO:1903317 regulation of protein maturation; GO:0050817 coagulation; GO:0060548 negative regulation of cell death; GO:0050794 regulation of cellular process; GO:0051640 organelle localization; GO:0030449 regulation of complement activation; GO:0044707 single-multicellular organism process; GO:0046907 intracellular transport; GO:2000257 regulation of protein activation cascade; GO:0002283 neutrophil activation involved in immune response; GO:0042127 regulation of cell proliferation; GO:0043067 regulation of programmed cell death; GO:0010955 negative regulation of protein processing; GO:0002920 regulation of humoral immune response; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:2000258 negative regulation of protein activation cascade; GO:0050867 positive regulation of cell activation; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:0006461 protein complex assembly; GO:0045861 negative regulation of proteolysis; GO:0045785 positive regulation of cell adhesion; GO:0006950 response to stress; GO:0090114 COPII-coated vesicle budding; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0032101 regulation of response to external stimulus; GO:0001971 negative regulation of activation of membrane attack complex; GO:0030162 regulation of proteolysis; GO:0051656 establishment of organelle localization; GO:0002263 cell activation involved in immune response; GO:0009892 negative regulation of metabolic process; GO:1903039 positive regulation of leukocyte cell-cell adhesion; GO:0030155 regulation of cell adhesion; GO:0002696 positive regulation of leukocyte activation; GO:0045055 regulated exocytosis; GO:0050870 positive regulation of T cell activation; GO:0006996 organelle organization; GO:0006900 membrane budding; GO:0061024 membrane organization; GO:0070613 regulation of protein processing; GO:0001775 cell activation; GO:0006955 immune response; GO:0051179 localization; GO:0006887 exocytosis; GO:0008284 positive regulation of cell proliferation; GO:0050863 regulation of T cell activation; GO:0006901 vesicle coating; GO:0048207 vesicle targeting, rough ER to cis-Golgi; GO:0044699 single-organism process; GO:0051249 regulation of lymphocyte activation; GO:0051234 establishment of localization; GO:0009611 response to wounding; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0050671 positive regulation of lymphocyte proliferation; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0070663 regulation of leukocyte proliferation; GO:0050777 negative regulation of immune response; GO:0002697 regulation of immune effector process; GO:0002274 myeloid leukocyte activation; GO:0010468 regulation of gene expression; GO:0051650 establishment of vesicle localization; GO:0071822 protein complex subunit organization; GO:0002446 neutrophil mediated immunity; GO:0048522 positive regulation of cellular process; GO:0051251 positive regulation of lymphocyte activation; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0002683 negative regulation of immune system process; GO:0050789 regulation of biological process; GO:0050865 regulation of cell activation; GO:0032268 regulation of cellular protein metabolic process; GO:0032940 secretion by cell; GO:0019222 regulation of metabolic process; GO:0043299 leukocyte degranulation; GO:0070271 protein complex biogenesis; GO:0016043 cellular component organization; GO:0043069 negative regulation of programmed cell death; GO:0042102 positive regulation of T cell proliferation; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0048193 Golgi vesicle transport; GO:0002673 regulation of acute inflammatory response; GO:0006903 vesicle targeting; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0002921 negative regulation of humoral immune response; GO:0007599 hemostasis; GO:0043066 negative regulation of apoptotic process; GO:0051648 vesicle localization; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0050878 regulation of body fluid levels; GO:0022409 positive regulation of cell-cell adhesion; GO:0010629 negative regulation of gene expression; GO:0016050 vesicle organization; GO:0042129 regulation of T cell proliferation; GO:0048585 negative regulation of response to stimulus; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0022407 regulation of cell-cell adhesion; GO:0051641 cellular localization; GO:0043933 macromolecular complex subunit organization; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0070665 positive regulation of leukocyte proliferation; GO:0042060 wound healing; GO:0051246 regulation of protein metabolic process; GO:0002684 positive regulation of immune system process; GO:0050727 regulation of inflammatory response; GO:0051248 negative regulation of protein metabolic process; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0009897 external side of plasma membrane; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0043209 myelin sheath; GO:0099503 secretory vesicle; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0005924 cell-substrate adherens junction; GO:0098552 side of membrane; GO:0031226 intrinsic component of plasma membrane; GO:0070161 anchoring junction; GO:0012506 vesicle membrane; GO:0030135 coated vesicle; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0031362 anchored component of external side of plasma membrane; GO:0030667 secretory granule membrane; GO:0030133 transport vesicle; GO:0042383 sarcolemma; GO:0043230 extracellular organelle; GO:0030658 transport vesicle membrane; GO:0005783 endoplasmic reticulum; GO:0043218 compact myelin; GO:0005615 extracellular space; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0030662 coated vesicle membrane; GO:0070821 tertiary granule membrane; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0005912 adherens junction; GO:0044431 Golgi apparatus part; GO:0030141 secretory granule; GO:0035579 specific granule membrane; GO:0012507 ER to Golgi transport vesicle membrane; GO:0031233 intrinsic component of external side of plasma membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane; GO:0044446 intracellular organelle part; GO:0031225 anchored component of membrane; GO:0070820 tertiary granule; GO:0000139 Golgi membrane; GO:0030134 ER to Golgi transport vesicle; GO:0012505 endomembrane system; GO:0046658 anchored component of plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0044432 endoplasmic reticulum part; GO:0005793 endoplasmic reticulum-Golgi intermediate compartment; GO:0042581 specific granule; GO:0009986 cell surface; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:0001848 complement binding; GO:0005515 protein binding; GO:0005488 binding; ","K04008","CD59; CD59 antigen","hsa04610 Complement and coagulation cascades - Homo sapiens (human); hsa04640 Hematopoietic cell lineage - Homo sapiens (human); ","IPR016054; ","Ly-6 antigen/uPA receptor-like; \r"]
["P14174","Macrophage migration inhibitory factor OS=Homo sapiens OX=9606 GN=MIF","MIF",12.476,10.598,23.5,3,10,3,1.073,0.955,1.089,0.911,1.071,0.88,0.918,0.3,"cyto_nucl\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0002694 regulation of leukocyte activation; GO:0010941 regulation of cell death; GO:0090342 regulation of cell aging; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0010564 regulation of cell cycle process; GO:0008610 lipid biosynthetic process; GO:0048145 regulation of fibroblast proliferation; GO:0030888 regulation of B cell proliferation; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0008152 metabolic process; GO:0048146 positive regulation of fibroblast proliferation; GO:0032946 positive regulation of mononuclear cell proliferation; GO:0032305 positive regulation of icosanoid secretion; GO:1902165 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; GO:0065003 macromolecular complex assembly; GO:0044093 positive regulation of molecular function; GO:0032306 regulation of prostaglandin secretion; GO:0033138 positive regulation of peptidyl-serine phosphorylation; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0061078 positive regulation of prostaglandin secretion involved in immune response; GO:0080090 regulation of primary metabolic process; GO:0046457 prostanoid biosynthetic process; GO:0050864 regulation of B cell activation; GO:0002905 regulation of mature B cell apoptotic process; GO:0070229 negative regulation of lymphocyte apoptotic process; GO:0044763 single-organism cellular process; GO:2000193 positive regulation of fatty acid transport; GO:0048870 cell motility; GO:0006935 chemotaxis; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0050776 regulation of immune response; GO:0006810 transport; GO:1902532 negative regulation of intracellular signal transduction; GO:0080135 regulation of cellular response to stress; GO:1902253 regulation of intrinsic apoptotic signaling pathway by p53 class mediator; GO:0048583 regulation of response to stimulus; GO:0032892 positive regulation of organic acid transport; GO:0051223 regulation of protein transport; GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production; GO:0060548 negative regulation of cell death; GO:0043436 oxoacid metabolic process; GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator; GO:0033559 unsaturated fatty acid metabolic process; GO:0002718 regulation of cytokine production involved in immune response; GO:0001819 positive regulation of cytokine production; GO:0048519 negative regulation of biological process; GO:0001516 prostaglandin biosynthetic process; GO:0050867 positive regulation of cell activation; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0050778 positive regulation of immune response; GO:1901797 negative regulation of signal transduction by p53 class mediator; GO:0044711 single-organism biosynthetic process; GO:0006950 response to stress; GO:0072331 signal transduction by p53 class mediator; GO:0008283 cell proliferation; GO:0032101 regulation of response to external stimulus; GO:0002376 immune system process; GO:0033033 negative regulation of myeloid cell apoptotic process; GO:0002263 cell activation involved in immune response; GO:1901576 organic substance biosynthetic process; GO:0006974 cellular response to DNA damage stimulus; GO:0070207 protein homotrimerization; GO:0002696 positive regulation of leukocyte activation; GO:0045055 regulated exocytosis; GO:0031325 positive regulation of cellular metabolic process; GO:0044283 small molecule biosynthetic process; GO:0006955 immune response; GO:2000107 negative regulation of leukocyte apoptotic process; GO:0072330 monocarboxylic acid biosynthetic process; GO:0008284 positive regulation of cell proliferation; GO:0051093 negative regulation of developmental process; GO:0051674 localization of cell; GO:0009968 negative regulation of signal transduction; GO:0016053 organic acid biosynthetic process; GO:0032308 positive regulation of prostaglandin secretion; GO:0032890 regulation of organic acid transport; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:0051046 regulation of secretion; GO:0044699 single-organism process; GO:0033032 regulation of myeloid cell apoptotic process; GO:0009058 biosynthetic process; GO:0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response; GO:0007165 signal transduction; GO:0010739 positive regulation of protein kinase A signaling; GO:0009893 positive regulation of metabolic process; GO:0032642 regulation of chemokine production; GO:0070663 regulation of leukocyte proliferation; GO:0033674 positive regulation of kinase activity; GO:0051726 regulation of cell cycle; GO:0006629 lipid metabolic process; GO:0043902 positive regulation of multi-organism process; GO:0045937 positive regulation of phosphate metabolic process; GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage; GO:0002700 regulation of production of molecular mediator of immune response; GO:1903530 regulation of secretion by cell; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0046394 carboxylic acid biosynthetic process; GO:0032940 secretion by cell; GO:0006954 inflammatory response; GO:0065009 regulation of molecular function; GO:0006693 prostaglandin metabolic process; GO:0006952 defense response; GO:0070271 protein complex biogenesis; GO:0050715 positive regulation of cytokine secretion; GO:0051222 positive regulation of protein transport; GO:0032722 positive regulation of chemokine production; GO:0043549 regulation of kinase activity; GO:0016477 cell migration; GO:0016043 cellular component organization; GO:0070228 regulation of lymphocyte apoptotic process; GO:0045786 negative regulation of cell cycle; GO:0043069 negative regulation of programmed cell death; GO:0002831 regulation of response to biotic stimulus; GO:0060255 regulation of macromolecule metabolic process; GO:0032368 regulation of lipid transport; GO:0045087 innate immune response; GO:0071704 organic substance metabolic process; GO:0043408 regulation of MAPK cascade; GO:0043066 negative regulation of apoptotic process; GO:0023056 positive regulation of signaling; GO:0010647 positive regulation of cell communication; GO:0070206 protein trimerization; GO:0010629 negative regulation of gene expression; GO:0035556 intracellular signal transduction; GO:0051049 regulation of transport; GO:0002699 positive regulation of immune effector process; GO:0006692 prostanoid metabolic process; GO:0001932 regulation of protein phosphorylation; GO:0001934 positive regulation of protein phosphorylation; GO:0044249 cellular biosynthetic process; GO:0043085 positive regulation of catalytic activity; GO:0043933 macromolecular complex subunit organization; GO:0002366 leukocyte activation involved in immune response; GO:0010738 regulation of protein kinase A signaling; GO:0002720 positive regulation of cytokine production involved in immune response; GO:0042119 neutrophil activation; GO:2000106 regulation of leukocyte apoptotic process; GO:0002684 positive regulation of immune system process; GO:0019752 carboxylic acid metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0001817 regulation of cytokine production; GO:2000341 regulation of chemokine (C-X-C motif) ligand 2 production; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0032944 regulation of mononuclear cell proliferation; GO:0045321 leukocyte activation; GO:0007166 cell surface receptor signaling pathway; GO:0002903 negative regulation of B cell apoptotic process; GO:0071157 negative regulation of cell cycle arrest; GO:0009605 response to external stimulus; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0032787 monocarboxylic acid metabolic process; GO:0010562 positive regulation of phosphorus metabolic process; GO:0042327 positive regulation of phosphorylation; GO:0051347 positive regulation of transferase activity; GO:1902229 regulation of intrinsic apoptotic signaling pathway in response to DNA damage; GO:0006690 icosanoid metabolic process; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0051174 regulation of phosphorus metabolic process; GO:0002443 leukocyte mediated immunity; GO:0044281 small molecule metabolic process; GO:0043269 regulation of ion transport; GO:0050707 regulation of cytokine secretion; GO:0050670 regulation of lymphocyte proliferation; GO:0031323 regulation of cellular metabolic process; GO:0032303 regulation of icosanoid secretion; GO:2001021 negative regulation of response to DNA damage stimulus; GO:0007569 cell aging; GO:0050900 leukocyte migration; GO:0010948 negative regulation of cell cycle process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0050714 positive regulation of protein secretion; GO:0090344 negative regulation of cell aging; GO:0010604 positive regulation of macromolecule metabolic process; GO:0002833 positive regulation of response to biotic stimulus; GO:0002682 regulation of immune system process; GO:0042330 taxis; GO:0051047 positive regulation of secretion; GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0002283 neutrophil activation involved in immune response; GO:0042127 regulation of cell proliferation; GO:2001020 regulation of response to DNA damage stimulus; GO:0051260 protein homooligomerization; GO:0031399 regulation of protein modification process; GO:0030890 positive regulation of B cell proliferation; GO:0043067 regulation of programmed cell death; GO:0071902 positive regulation of protein serine/threonine kinase activity; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:0032844 regulation of homeostatic process; GO:0051239 regulation of multicellular organismal process; GO:0051259 protein oligomerization; GO:0030330 DNA damage response, signal transduction by p53 class mediator; GO:0070372 regulation of ERK1 and ERK2 cascade; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0051338 regulation of transferase activity; GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway; GO:0032880 regulation of protein localization; GO:0009966 regulation of signal transduction; GO:0006461 protein complex assembly; GO:0045787 positive regulation of cell cycle; GO:2000191 regulation of fatty acid transport; GO:1902531 regulation of intracellular signal transduction; GO:0033135 regulation of peptidyl-serine phosphorylation; GO:0043900 regulation of multi-organism process; GO:0016192 vesicle-mediated transport; GO:1901570 fatty acid derivative biosynthetic process; GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0043270 positive regulation of ion transport; GO:0043406 positive regulation of MAP kinase activity; GO:0051247 positive regulation of protein metabolic process; GO:1904951 positive regulation of establishment of protein localization; GO:0006928 movement of cell or subcellular component; GO:0001775 cell activation; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0006887 exocytosis; GO:0002702 positive regulation of production of molecular mediator of immune response; GO:0090237 regulation of arachidonic acid secretion; GO:0043030 regulation of macrophage activation; GO:0044070 regulation of anion transport; GO:1902533 positive regulation of intracellular signal transduction; GO:1901568 fatty acid derivative metabolic process; GO:0051249 regulation of lymphocyte activation; GO:0002906 negative regulation of mature B cell apoptotic process; GO:0051234 establishment of localization; GO:2001233 regulation of apoptotic signaling pathway; GO:0046456 icosanoid biosynthetic process; GO:0050671 positive regulation of lymphocyte proliferation; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:2001243 negative regulation of intrinsic apoptotic signaling pathway; GO:0022607 cellular component assembly; GO:0032103 positive regulation of response to external stimulus; GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator; GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; GO:0002902 regulation of B cell apoptotic process; GO:0002697 regulation of immune effector process; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0071822 protein complex subunit organization; GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway; GO:0002446 neutrophil mediated immunity; GO:0048522 positive regulation of cellular process; GO:0006636 unsaturated fatty acid biosynthetic process; GO:0051251 positive regulation of lymphocyte activation; GO:0006633 fatty acid biosynthetic process; GO:0051050 positive regulation of transport; GO:0002683 negative regulation of immune system process; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0050865 regulation of cell activation; GO:0042221 response to chemical; GO:1903532 positive regulation of secretion by cell; GO:0007568 aging; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0040011 locomotion; GO:0043299 leukocyte degranulation; GO:0006082 organic acid metabolic process; GO:0090238 positive regulation of arachidonic acid secretion; GO:0045859 regulation of protein kinase activity; GO:0050730 regulation of peptidyl-tyrosine phosphorylation; GO:0002252 immune effector process; GO:0043405 regulation of MAP kinase activity; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0070201 regulation of establishment of protein localization; GO:0050871 positive regulation of B cell activation; GO:1901796 regulation of signal transduction by p53 class mediator; GO:0042770 signal transduction in response to DNA damage; GO:0036230 granulocyte activation; GO:0050708 regulation of protein secretion; GO:0009987 cellular process; GO:0050918 positive chemotaxis; GO:0071156 regulation of cell cycle arrest; GO:0031401 positive regulation of protein modification process; GO:0006631 fatty acid metabolic process; GO:0032845 negative regulation of homeostatic process; GO:0048585 negative regulation of response to stimulus; GO:0045860 positive regulation of protein kinase activity; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0070665 positive regulation of leukocyte proliferation; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:2001242 regulation of intrinsic apoptotic signaling pathway; GO:0032370 positive regulation of lipid transport; GO:0009967 positive regulation of signal transduction; GO:0043410 positive regulation of MAPK cascade; GO:0070374 positive regulation of ERK1 and ERK2 cascade; GO:1903793 positive regulation of anion transport; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0043209 myelin sheath; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0009986 cell surface; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005125 cytokine activity; GO:0016853 isomerase activity; GO:0003824 catalytic activity; GO:0005102 receptor binding; GO:0005488 binding; GO:0005126 cytokine receptor binding; GO:0005515 protein binding; GO:0050178 phenylpyruvate tautomerase activity; GO:0016860 intramolecular oxidoreductase activity; GO:0004167 dopachrome isomerase activity; GO:0016862 intramolecular oxidoreductase activity, interconverting keto- and enol-groups; GO:0042056 chemoattractant activity; GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds; ","K07253","MIF; phenylpyruvate tautomerase [EC:5.3.2.1]","hsa00360 Phenylalanine metabolism - Homo sapiens (human); hsa00350 Tyrosine metabolism - Homo sapiens (human); ","IPR014347; ","Tautomerase/MIF superfamily; \r"]
["P14207","Folate receptor beta OS=Homo sapiens OX=9606 GN=FOLR2","FOLR2",29.279,38.656,25.5,5,8,5,0.957,1.105,1.018,0.964,1.034,0.962,0.961,0.466,"extracellular\r","GO:0072337 modified amino acid transport; GO:0001101 response to acid chemical; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0051593 response to folic acid; GO:0042157 lipoprotein metabolic process; GO:0051234 establishment of localization; GO:0009605 response to external stimulus; GO:0015884 folic acid transport; GO:0008152 metabolic process; GO:0007154 cell communication; GO:0009719 response to endogenous stimulus; GO:0051180 vitamin transport; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0042886 amide transport; GO:0042158 lipoprotein biosynthetic process; GO:0070887 cellular response to chemical stimulus; GO:0033273 response to vitamin; GO:0044765 single-organism transport; GO:0071231 cellular response to folic acid; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0051181 cofactor transport; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0006732 coenzyme metabolic process; GO:0043603 cellular amide metabolic process; GO:0046942 carboxylic acid transport; GO:0051186 cofactor metabolic process; GO:0006810 transport; GO:0071417 cellular response to organonitrogen compound; GO:0010243 response to organonitrogen compound; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:1901699 cellular response to nitrogen compound; GO:0044710 single-organism metabolic process; GO:0006954 inflammatory response; GO:0044260 cellular macromolecule metabolic process; GO:1901698 response to nitrogen compound; GO:0019222 regulation of metabolic process; GO:0006497 protein lipidation; GO:0006464 cellular protein modification process; GO:0006952 defense response; GO:0006082 organic acid metabolic process; GO:0006760 folic acid-containing compound metabolic process; GO:0036211 protein modification process; GO:0043436 oxoacid metabolic process; GO:0050794 regulation of cellular process; GO:0043687 post-translational protein modification; GO:0043648 dicarboxylic acid metabolic process; GO:0042127 regulation of cell proliferation; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:1901700 response to oxygen-containing compound; GO:0044267 cellular protein metabolic process; GO:0050896 response to stimulus; GO:0050758 regulation of thymidylate synthase biosynthetic process; GO:0031669 cellular response to nutrient levels; GO:0046655 folic acid metabolic process; GO:0071704 organic substance metabolic process; GO:0071295 cellular response to vitamin; GO:0009991 response to extracellular stimulus; GO:0006766 vitamin metabolic process; GO:1902578 single-organism localization; GO:0006575 cellular modified amino acid metabolic process; GO:0046483 heterocycle metabolic process; GO:0071229 cellular response to acid chemical; GO:0009889 regulation of biosynthetic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0006898 receptor-mediated endocytosis; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006767 water-soluble vitamin metabolic process; GO:0006501 C-terminal protein lipidation; GO:0006950 response to stress; GO:0016192 vesicle-mediated transport; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0071407 cellular response to organic cyclic compound; GO:0071496 cellular response to external stimulus; GO:0010556 regulation of macromolecule biosynthetic process; GO:0010033 response to organic substance; GO:0006897 endocytosis; GO:0007584 response to nutrient; GO:0018410 C-terminal protein amino acid modification; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0015849 organic acid transport; GO:1901576 organic substance biosynthetic process; GO:0042558 pteridine-containing compound metabolic process; GO:0044249 cellular biosynthetic process; GO:0031668 cellular response to extracellular stimulus; GO:0006820 anion transport; GO:0015711 organic anion transport; GO:1901701 cellular response to oxygen-containing compound; GO:0034645 cellular macromolecule biosynthetic process; GO:0006811 ion transport; GO:0071495 cellular response to endogenous stimulus; GO:0031670 cellular response to nutrient; GO:0051246 regulation of protein metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0006835 dicarboxylic acid transport; GO:0031667 response to nutrient levels; GO:0051179 localization; GO:0043412 macromolecule modification; GO:0071705 nitrogen compound transport; GO:0008284 positive regulation of cell proliferation; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0031226 intrinsic component of plasma membrane; GO:0009897 external side of plasma membrane; GO:0071944 cell periphery; GO:0031225 anchored component of membrane; GO:0031224 intrinsic component of membrane; GO:0005623 cell; GO:0005576 extracellular region; GO:0046658 anchored component of plasma membrane; GO:0005886 plasma membrane; GO:0031362 anchored component of external side of plasma membrane; GO:0044459 plasma membrane part; GO:0044425 membrane part; GO:0044464 cell part; GO:0009986 cell surface; GO:0031233 intrinsic component of external side of plasma membrane; GO:0098552 side of membrane; ","GO:0019842 vitamin binding; GO:0043167 ion binding; GO:0005542 folic acid binding; GO:0043177 organic acid binding; GO:0038024 cargo receptor activity; GO:0051183 vitamin transporter activity; GO:0008144 drug binding; GO:0033218 amide binding; GO:0051184 cofactor transporter activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0051870 methotrexate binding; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0072341 modified amino acid binding; GO:0031406 carboxylic acid binding; GO:0005488 binding; GO:0043168 anion binding; GO:0008517 folic acid transporter activity; GO:0061714 folic acid receptor activity; GO:0005215 transporter activity; GO:0036094 small molecule binding; ","K13649","FOLR; folate receptor","hsa01523 Antifolate resistance - Homo sapiens (human); hsa04144 Endocytosis - Homo sapiens (human); ","IPR018143; ","Folate receptor-like; \r"]
["P14209","CD99 antigen OS=Homo sapiens OX=9606 GN=CD99","CD99",18.848,22.574,15.1,3,8,3,1.167,1.08,1.085,0.875,0.84,0.829,0.764,0.00084,"extracellular\r","GO:0007155 cell adhesion; GO:0022610 biological adhesion; ","GO:0016020 membrane; GO:0031226 intrinsic component of plasma membrane; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0070161 anchoring junction; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0005925 focal adhesion; GO:0044459 plasma membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0005912 adherens junction; GO:0030055 cell-substrate junction; GO:0005924 cell-substrate adherens junction; ",null,"K06520","CD99; CD99 antigen","hsa04670 Leukocyte transendothelial migration - Homo sapiens (human); hsa04514 Cell adhesion molecules (CAMs) - Homo sapiens (human); "]
["P14314","Glucosidase 2 subunit beta OS=Homo sapiens OX=9606 GN=PRKCSH","PRKCSH",59.425,163.86,28.6,17,34,17,1.018,1.035,1.039,0.947,1.002,0.989,0.95,0.0476,"extracellular\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0051716 cellular response to stimulus; GO:0035556 intracellular signal transduction; GO:0009100 glycoprotein metabolic process; GO:0044699 single-organism process; GO:0044238 primary metabolic process; GO:0023052 signaling; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0006457 protein folding; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0050789 regulation of biological process; GO:0007154 cell communication; GO:0006491 N-glycan processing; GO:0044260 cellular macromolecule metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0009987 cellular process; GO:0065007 biological regulation; ","GO:0005788 endoplasmic reticulum lumen; GO:0043229 intracellular organelle; GO:0005783 endoplasmic reticulum; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044432 endoplasmic reticulum part; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0005488 binding; GO:0019901 protein kinase binding; GO:0043167 ion binding; GO:0044325 ion channel binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005080 protein kinase C binding; GO:0005515 protein binding; GO:0005509 calcium ion binding; GO:0019900 kinase binding; GO:0019899 enzyme binding; GO:0051219 phosphoprotein binding; ","K08288","PRKCSH; protein kinase C substrate 80K-H","hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); ","IPR011992; IPR002048; IPR009011; IPR028146; ","\"EF-hand domain pair; EF-hand domain; Mannose-6-phosphate receptor binding domain; Glucosidase II beta subunit, N-terminal; \"\r"]
["P14317","Hematopoietic lineage cell-specific protein OS=Homo sapiens OX=9606 GN=HCLS1","HCLS1",54.013,7.8751,8,3,3,3,0.987,0.967,0.905,0.935,1.059,1.15,1.1,0.233,"cytoplasm\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0010941 regulation of cell death; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0051896 regulation of protein kinase B signaling; GO:0002262 myeloid cell homeostasis; GO:1903533 regulation of protein targeting; GO:0009891 positive regulation of biosynthetic process; GO:0030832 regulation of actin filament length; GO:0071345 cellular response to cytokine stimulus; GO:0030041 actin filament polymerization; GO:0030852 regulation of granulocyte differentiation; GO:0030036 actin cytoskeleton organization; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0065003 macromolecular complex assembly; GO:0032535 regulation of cellular component size; GO:0009719 response to endogenous stimulus; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0051493 regulation of cytoskeleton organization; GO:0033138 positive regulation of peptidyl-serine phosphorylation; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0046427 positive regulation of JAK-STAT cascade; GO:0000122 negative regulation of transcription from RNA polymerase II promoter; GO:0044763 single-organism cellular process; GO:0008154 actin polymerization or depolymerization; GO:0002520 immune system development; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:2000251 positive regulation of actin cytoskeleton reorganization; GO:0048872 homeostasis of number of cells; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0030854 positive regulation of granulocyte differentiation; GO:0030218 erythrocyte differentiation; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051223 regulation of protein transport; GO:0002682 regulation of immune system process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0060548 negative regulation of cell death; GO:0097435 supramolecular fiber organization; GO:0051094 positive regulation of developmental process; GO:0042307 positive regulation of protein import into nucleus; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:1902903 regulation of supramolecular fiber organization; GO:0050794 regulation of cellular process; GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation; GO:0044707 single-multicellular organism process; GO:0042127 regulation of cell proliferation; GO:0042509 regulation of tyrosine phosphorylation of STAT protein; GO:0032956 regulation of actin cytoskeleton organization; GO:0031399 regulation of protein modification process; GO:0043067 regulation of programmed cell death; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0045597 positive regulation of cell differentiation; GO:0051239 regulation of multicellular organismal process; GO:0060341 regulation of cellular localization; GO:0042990 regulation of transcription factor import into nucleus; GO:1903706 regulation of hemopoiesis; GO:0045892 negative regulation of transcription, DNA-templated; GO:0014066 regulation of phosphatidylinositol 3-kinase signaling; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0007275 multicellular organism development; GO:0032880 regulation of protein localization; GO:0007010 cytoskeleton organization; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0009966 regulation of signal transduction; GO:0006461 protein complex assembly; GO:1904892 regulation of STAT cascade; GO:0051254 positive regulation of RNA metabolic process; GO:1902531 regulation of intracellular signal transduction; GO:0051495 positive regulation of cytoskeleton organization; GO:0048731 system development; GO:0033135 regulation of peptidyl-serine phosphorylation; GO:0002376 immune system process; GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein; GO:0032970 regulation of actin filament-based process; GO:0002763 positive regulation of myeloid leukocyte differentiation; GO:0010033 response to organic substance; GO:0009892 negative regulation of metabolic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:1900182 positive regulation of protein localization to nucleus; GO:0008064 regulation of actin polymerization or depolymerization; GO:0009890 negative regulation of biosynthetic process; GO:0051247 positive regulation of protein metabolic process; GO:0046822 regulation of nucleocytoplasmic transport; GO:1904951 positive regulation of establishment of protein localization; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0002761 regulation of myeloid leukocyte differentiation; GO:0031325 positive regulation of cellular metabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0048584 positive regulation of response to stimulus; GO:2000107 negative regulation of leukocyte apoptotic process; GO:0050793 regulation of developmental process; GO:1903827 regulation of cellular protein localization; GO:1904591 positive regulation of protein import; GO:0008284 positive regulation of cell proliferation; GO:0030833 regulation of actin filament polymerization; GO:0048869 cellular developmental process; GO:0045637 regulation of myeloid cell differentiation; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0051253 negative regulation of RNA metabolic process; GO:1904894 positive regulation of STAT cascade; GO:0051130 positive regulation of cellular component organization; GO:0034101 erythrocyte homeostasis; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0042306 regulation of protein import into nucleus; GO:1902107 positive regulation of leukocyte differentiation; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling; GO:0009893 positive regulation of metabolic process; GO:0022607 cellular component assembly; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0046824 positive regulation of nucleocytoplasmic transport; GO:0032271 regulation of protein polymerization; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0070887 cellular response to chemical stimulus; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0045937 positive regulation of phosphate metabolic process; GO:0071822 protein complex subunit organization; GO:0034097 response to cytokine; GO:0031326 regulation of cellular biosynthetic process; GO:0048522 positive regulation of cellular process; GO:0032386 regulation of intracellular transport; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051050 positive regulation of transport; GO:1902589 single-organism organelle organization; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0043254 regulation of protein complex assembly; GO:0042221 response to chemical; GO:0010638 positive regulation of organelle organization; GO:0045639 positive regulation of myeloid cell differentiation; GO:1902679 negative regulation of RNA biosynthetic process; GO:1902105 regulation of leukocyte differentiation; GO:1900180 regulation of protein localization to nucleus; GO:0051258 protein polymerization; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0070271 protein complex biogenesis; GO:0048856 anatomical structure development; GO:0051222 positive regulation of protein transport; GO:2000026 regulation of multicellular organismal development; GO:0046425 regulation of JAK-STAT cascade; GO:0016043 cellular component organization; GO:0043069 negative regulation of programmed cell death; GO:0090316 positive regulation of intracellular protein transport; GO:0050730 regulation of peptidyl-tyrosine phosphorylation; GO:1903829 positive regulation of cellular protein localization; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0007015 actin filament organization; GO:0044087 regulation of cellular component biogenesis; GO:0031324 negative regulation of cellular metabolic process; GO:1904589 regulation of protein import; GO:0050896 response to stimulus; GO:0045651 positive regulation of macrophage differentiation; GO:0070201 regulation of establishment of protein localization; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:0043066 negative regulation of apoptotic process; GO:0023056 positive regulation of signaling; GO:2000249 regulation of actin cytoskeleton reorganization; GO:0010647 positive regulation of cell communication; GO:0033157 regulation of intracellular protein transport; GO:0009987 cellular process; GO:0042993 positive regulation of transcription factor import into nucleus; GO:0045595 regulation of cell differentiation; GO:0043623 cellular protein complex assembly; GO:0051897 positive regulation of protein kinase B signaling; GO:0034622 cellular macromolecular complex assembly; GO:1903708 positive regulation of hemopoiesis; GO:0006355 regulation of transcription, DNA-templated; GO:0030099 myeloid cell differentiation; GO:0010629 negative regulation of gene expression; GO:0035556 intracellular signal transduction; GO:0051049 regulation of transport; GO:0032388 positive regulation of intracellular transport; GO:0001932 regulation of protein phosphorylation; GO:0033043 regulation of organelle organization; GO:0031401 positive regulation of protein modification process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0001934 positive regulation of protein phosphorylation; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0048534 hematopoietic or lymphoid organ development; GO:0030097 hemopoiesis; GO:0043933 macromolecular complex subunit organization; GO:2000106 regulation of leukocyte apoptotic process; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0002684 positive regulation of immune system process; GO:0090066 regulation of anatomical structure size; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0051128 regulation of cellular component organization; GO:0009967 positive regulation of signal transduction; GO:0009725 response to hormone; GO:0045649 regulation of macrophage differentiation; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005667 transcription factor complex; GO:0005623 cell; GO:0005829 cytosol; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0008092 cytoskeletal protein binding; GO:0001085 RNA polymerase II transcription factor binding; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0019901 protein kinase binding; GO:0003779 actin binding; GO:0019904 protein domain specific binding; GO:0005515 protein binding; GO:0019900 kinase binding; GO:0017124 SH3 domain binding; GO:0019899 enzyme binding; GO:0008134 transcription factor binding; GO:0032403 protein complex binding; ","K06106","CTTN; cortactin","hsa05100 Bacterial invasion of epithelial cells - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa04530 Tight junction - Homo sapiens (human); hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human); hsa05131 Shigellosis - Homo sapiens (human); ","IPR001452; ","SH3 domain; \r"]
["P14324","Farnesyl pyrophosphate synthase OS=Homo sapiens OX=9606 GN=FDPS","FDPS",48.275,38.398,16.9,8,17,8,1.238,1.207,1.106,0.782,0.852,0.899,0.713,0.0031,"mitochondria\r","GO:0033384 geranyl diphosphate biosynthetic process; GO:1901615 organic hydroxy compound metabolic process; GO:1902652 secondary alcohol metabolic process; GO:0006066 alcohol metabolic process; GO:1902653 secondary alcohol biosynthetic process; GO:0008654 phospholipid biosynthetic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044255 cellular lipid metabolic process; GO:0044764 multi-organism cellular process; GO:0016125 sterol metabolic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0008610 lipid biosynthetic process; GO:0008299 isoprenoid biosynthetic process; GO:0016126 sterol biosynthetic process; GO:0008152 metabolic process; GO:0006695 cholesterol biosynthetic process; GO:0016032 viral process; GO:0044419 interspecies interaction between organisms; GO:0016114 terpenoid biosynthetic process; GO:0009987 cellular process; GO:0045338 farnesyl diphosphate metabolic process; GO:0006629 lipid metabolic process; GO:0006720 isoprenoid metabolic process; GO:0045337 farnesyl diphosphate biosynthetic process; GO:0008203 cholesterol metabolic process; GO:0044711 single-organism biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0008202 steroid metabolic process; GO:0046165 alcohol biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:1901617 organic hydroxy compound biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0051704 multi-organism process; GO:0044249 cellular biosynthetic process; GO:0006694 steroid biosynthetic process; GO:0090407 organophosphate biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0044283 small molecule biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0006721 terpenoid metabolic process; GO:0006644 phospholipid metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0033383 geranyl diphosphate metabolic process; ","GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0004337 geranyltranstransferase activity; GO:0004659 prenyltransferase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0003676 nucleic acid binding; GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0004161 dimethylallyltranstransferase activity; GO:0016740 transferase activity; ","K00787","FDPS; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10]","hsa05166 HTLV-I infection - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00900 Terpenoid backbone biosynthesis - Homo sapiens (human); hsa05164 Influenza A - Homo sapiens (human); ","IPR008949; ","Isoprenoid synthase domain; \r"]
["P14384","Carboxypeptidase M OS=Homo sapiens OX=9606 GN=CPM","CPM",50.513,20.253,14.7,6,7,6,1.03,0.925,1.108,0.931,1.083,0.928,0.96,0.612,"extracellular\r","GO:0043687 post-translational protein modification; GO:0006518 peptide metabolic process; GO:0044267 cellular protein metabolic process; GO:0009058 biosynthetic process; GO:0016485 protein processing; GO:0044237 cellular metabolic process; GO:0042157 lipoprotein metabolic process; GO:0071704 organic substance metabolic process; GO:0009653 anatomical structure morphogenesis; GO:0008152 metabolic process; GO:0006508 proteolysis; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0042158 lipoprotein biosynthetic process; GO:0032502 developmental process; GO:0006501 C-terminal protein lipidation; GO:0006807 nitrogen compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0044238 primary metabolic process; GO:0018410 C-terminal protein amino acid modification; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0006497 protein lipidation; GO:0006464 cellular protein modification process; GO:0010467 gene expression; GO:0051604 protein maturation; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:0048856 anatomical structure development; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0031225 anchored component of membrane; GO:0031224 intrinsic component of membrane; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0009986 cell surface; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0004180 carboxypeptidase activity; GO:0008233 peptidase activity; GO:0008238 exopeptidase activity; GO:0008235 metalloexopeptidase activity; GO:0043167 ion binding; GO:0016787 hydrolase activity; GO:0008237 metallopeptidase activity; GO:0008270 zinc ion binding; GO:0046914 transition metal ion binding; GO:0004181 metallocarboxypeptidase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0046872 metal ion binding; GO:0043169 cation binding; ","K01296",null,null,"IPR008969; IPR033842; IPR000834; IPR014766; ","\"Carboxypeptidase-like, regulatory domain; Carboxypeptidase M N-terminal domain; Peptidase M14, carboxypeptidase A; Carboxypeptidase, regulatory domain; \"\r"]
["P14406","Cytochrome c oxidase subunit 7A2, mitochondrial OS=Homo sapiens OX=9606 GN=COX7A2","COX7A2",9.3959,21.971,27.7,2,5,2,0.968,0.958,1.111,1.076,1.016,1.038,1.031,0.559,"mitochondria\r","GO:0098655 cation transmembrane transport; GO:0034220 ion transmembrane transport; GO:0098660 inorganic ion transmembrane transport; GO:0044699 single-organism process; GO:0006818 hydrogen transport; GO:0015992 proton transport; GO:0051234 establishment of localization; GO:0006810 transport; GO:0055085 transmembrane transport; GO:1902578 single-organism localization; GO:0006812 cation transport; GO:0006811 ion transport; GO:1902600 hydrogen ion transmembrane transport; GO:0051179 localization; GO:0015672 monovalent inorganic cation transport; GO:0098662 inorganic cation transmembrane transport; GO:0044765 single-organism transport; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0019866 organelle inner membrane; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005746 mitochondrial respiratory chain; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031975 envelope; GO:0070469 respiratory chain; GO:0043230 extracellular organelle; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0015075 ion transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0015077 monovalent inorganic cation transmembrane transporter activity; GO:0016676 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor; GO:0016675 oxidoreductase activity, acting on a heme group of donors; GO:0015078 hydrogen ion transmembrane transporter activity; GO:0015002 heme-copper terminal oxidase activity; GO:0016491 oxidoreductase activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0009055 electron carrier activity; GO:0004129 cytochrome-c oxidase activity; GO:0003824 catalytic activity; GO:0022890 inorganic cation transmembrane transporter activity; GO:0008324 cation transmembrane transporter activity; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; ","K02270","COX7A; cytochrome c oxidase subunit 7a","hsa04260 Cardiac muscle contraction - Homo sapiens (human); hsa05010 Alzheimer's disease - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); "]
["P14543","Nidogen-1 OS=Homo sapiens OX=9606 GN=NID1","NID1",136.38,57.522,12.8,15,18,14,1.094,1.078,1.075,0.912,0.904,0.914,0.841,1.55e-05,"extracellular\r","GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0044699 single-organism process; GO:0072001 renal system development; GO:0032835 glomerulus development; GO:0071711 basement membrane organization; GO:0022610 biological adhesion; GO:0043062 extracellular structure organization; GO:0022617 extracellular matrix disassembly; GO:0007160 cell-matrix adhesion; GO:0007155 cell adhesion; GO:0072006 nephron development; GO:0030198 extracellular matrix organization; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0032502 developmental process; GO:0001822 kidney development; GO:0032836 glomerular basement membrane development; GO:0045785 positive regulation of cell adhesion; GO:0048731 system development; GO:0044763 single-organism cellular process; GO:0032501 multicellular organismal process; GO:0048518 positive regulation of biological process; GO:0030155 regulation of cell adhesion; GO:0010811 positive regulation of cell-substrate adhesion; GO:0048513 animal organ development; GO:0001655 urogenital system development; GO:0050789 regulation of biological process; GO:0031589 cell-substrate adhesion; GO:0044767 single-organism developmental process; GO:0022411 cellular component disassembly; GO:0010810 regulation of cell-substrate adhesion; GO:0048856 anatomical structure development; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005623 cell; GO:0044420 extracellular matrix component; GO:0005576 extracellular region; GO:0005604 basement membrane; GO:0005605 basal lamina; GO:0031012 extracellular matrix; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0005578 proteinaceous extracellular matrix; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0043167 ion binding; GO:0044877 macromolecular complex binding; GO:0043394 proteoglycan binding; GO:0043237 laminin-1 binding; GO:0005515 protein binding; GO:0050840 extracellular matrix binding; GO:0097367 carbohydrate derivative binding; GO:0043236 laminin binding; GO:0005488 binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005518 collagen binding; GO:0005509 calcium ion binding; GO:0001948 glycoprotein binding; GO:0032403 protein complex binding; ","K06826",null,null,"IPR003886; IPR001881; IPR000742; IPR000716; IPR011042; IPR009030; IPR009017; IPR006605; IPR026823; IPR024731; IPR023413; ","\"NIDO domain; EGF-like calcium-binding domain; EGF-like domain; Thyroglobulin type-1; Six-bladed beta-propeller, TolB-like; Growth factor receptor cysteine-rich domain; Green fluorescent protein; G2 nidogen/fibulin G2F; Complement Clr-like EGF domain; EGF domain; Green fluorescent protein-like; \"\r"]
["P14550","Alcohol dehydrogenase [NADP(+)] OS=Homo sapiens OX=9606 GN=AKR1A1","AKR1A1",36.573,164.16,66.2,20,43,20,1.08,1.069,1.05,0.892,0.95,0.953,0.874,0.0042,"cytoplasm\r","GO:0019640 glucuronate catabolic process to xylulose 5-phosphate; GO:0046365 monosaccharide catabolic process; GO:0009110 vitamin biosynthetic process; GO:0016053 organic acid biosynthetic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0044272 sulfur compound biosynthetic process; GO:0006796 phosphate-containing compound metabolic process; GO:0006006 glucose metabolic process; GO:0051167 xylulose 5-phosphate metabolic process; GO:1901685 glutathione derivative metabolic process; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0042840 D-glucuronate catabolic process; GO:0042364 water-soluble vitamin biosynthetic process; GO:0032787 monocarboxylic acid metabolic process; GO:0006790 sulfur compound metabolic process; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0042839 D-glucuronate metabolic process; GO:0044763 single-organism cellular process; GO:0006081 cellular aldehyde metabolic process; GO:0072329 monocarboxylic acid catabolic process; GO:0005975 carbohydrate metabolic process; GO:0016052 carbohydrate catabolic process; GO:0090407 organophosphate biosynthetic process; GO:0046395 carboxylic acid catabolic process; GO:1901575 organic substance catabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0046394 carboxylic acid biosynthetic process; GO:0044710 single-organism metabolic process; GO:0006064 glucuronate catabolic process; GO:0006082 organic acid metabolic process; GO:0043436 oxoacid metabolic process; GO:0016051 carbohydrate biosynthetic process; GO:0046364 monosaccharide biosynthetic process; GO:0019853 L-ascorbic acid biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0006063 uronic acid metabolic process; GO:0071704 organic substance metabolic process; GO:0006766 vitamin metabolic process; GO:0005996 monosaccharide metabolic process; GO:0044248 cellular catabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0009987 cellular process; GO:0006767 water-soluble vitamin metabolic process; GO:0019852 L-ascorbic acid metabolic process; GO:0044724 single-organism carbohydrate catabolic process; GO:0044711 single-organism biosynthetic process; GO:0044712 single-organism catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044282 small molecule catabolic process; GO:1901159 xylulose 5-phosphate biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:1901687 glutathione derivative biosynthetic process; GO:0046185 aldehyde catabolic process; GO:0006793 phosphorus metabolic process; GO:0019585 glucuronate metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0016054 organic acid catabolic process; GO:0044283 small molecule biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0009056 catabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0019318 hexose metabolic process; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0016324 apical plasma membrane; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0098590 plasma membrane region; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0045177 apical part of cell; GO:0044444 cytoplasmic part; ","GO:0009055 electron carrier activity; GO:0016614 oxidoreductase activity, acting on CH-OH group of donors; GO:0004032 alditol:NADP+ 1-oxidoreductase activity; GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; GO:0047939 L-glucuronate reductase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0008106 alcohol dehydrogenase (NADP+) activity; GO:0005515 protein binding; GO:0004033 aldo-keto reductase (NADP) activity; GO:0016491 oxidoreductase activity; ","K00002","AKR1A1; alcohol dehydrogenase (NADP+) [EC:1.1.1.2]","hsa00040 Pentose and glucuronate interconversions - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00561 Glycerolipid metabolism - Homo sapiens (human); hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human); ","IPR023210; ","NADP-dependent oxidoreductase domain; \r"]
["P14618","Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM","PKM",57.936,323.31,71.8,38,123,37,0.946,0.942,0.979,1.029,1.04,1.054,1.089,0.00366,"cytoplasm\r","GO:0009116 nucleoside metabolic process; GO:0045321 leukocyte activation; GO:0006165 nucleoside diphosphate phosphorylation; GO:0019362 pyridine nucleotide metabolic process; GO:0006096 glycolytic process; GO:0009185 ribonucleoside diphosphate metabolic process; GO:0044237 cellular metabolic process; GO:0006006 glucose metabolic process; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0009719 response to endogenous stimulus; GO:0032787 monocarboxylic acid metabolic process; GO:0019693 ribose phosphate metabolic process; GO:1901652 response to peptide; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0009179 purine ribonucleoside diphosphate metabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0061620 glycolytic process through glucose-6-phosphate; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0006732 coenzyme metabolic process; GO:0005975 carbohydrate metabolic process; GO:0061718 glucose catabolic process to pyruvate; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0010243 response to organonitrogen compound; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0019674 NAD metabolic process; GO:0044710 single-organism metabolic process; GO:1901698 response to nitrogen compound; GO:0032869 cellular response to insulin stimulus; GO:0009126 purine nucleoside monophosphate metabolic process; GO:0043436 oxoacid metabolic process; GO:0016310 phosphorylation; GO:0002283 neutrophil activation involved in immune response; GO:0046496 nicotinamide nucleotide metabolic process; GO:0009259 ribonucleotide metabolic process; GO:1901700 response to oxygen-containing compound; GO:0006735 NADH regeneration; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0009119 ribonucleoside metabolic process; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0009141 nucleoside triphosphate metabolic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0002263 cell activation involved in immune response; GO:0006163 purine nucleotide metabolic process; GO:0045055 regulated exocytosis; GO:0006793 phosphorus metabolic process; GO:0001775 cell activation; GO:0019637 organophosphate metabolic process; GO:0012501 programmed cell death; GO:0019320 hexose catabolic process; GO:0051179 localization; GO:0006955 immune response; GO:0006887 exocytosis; GO:0019318 hexose metabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0006757 ATP generation from ADP; GO:0046365 monosaccharide catabolic process; GO:0042278 purine nucleoside metabolic process; GO:0046031 ADP metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0046939 nucleotide phosphorylation; GO:0009135 purine nucleoside diphosphate metabolic process; GO:0072524 pyridine-containing compound metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0061615 glycolytic process through fructose-6-phosphate; GO:0051234 establishment of localization; GO:1901653 cellular response to peptide; GO:0006753 nucleoside phosphate metabolic process; GO:0070887 cellular response to chemical stimulus; GO:0002274 myeloid leukocyte activation; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0055114 oxidation-reduction process; GO:0002446 neutrophil mediated immunity; GO:1901360 organic cyclic compound metabolic process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0051186 cofactor metabolic process; GO:0016052 carbohydrate catabolic process; GO:0071417 cellular response to organonitrogen compound; GO:0044723 single-organism carbohydrate metabolic process; GO:0032868 response to insulin; GO:0042221 response to chemical; GO:0043434 response to peptide hormone; GO:1901699 cellular response to nitrogen compound; GO:0032940 secretion by cell; GO:0032870 cellular response to hormone stimulus; GO:1901657 glycosyl compound metabolic process; GO:0043299 leukocyte degranulation; GO:0006082 organic acid metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0002252 immune effector process; GO:0006734 NADH metabolic process; GO:0071310 cellular response to organic substance; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0061621 canonical glycolysis; GO:0006090 pyruvate metabolic process; GO:0071375 cellular response to peptide hormone stimulus; GO:0005996 monosaccharide metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0036230 granulocyte activation; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0009132 nucleoside diphosphate metabolic process; GO:0046034 ATP metabolic process; GO:0044724 single-organism carbohydrate catabolic process; GO:0044712 single-organism catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044282 small molecule catabolic process; GO:0043312 neutrophil degranulation; GO:0002366 leukocyte activation involved in immune response; GO:0046128 purine ribonucleoside metabolic process; GO:0006007 glucose catabolic process; GO:0042119 neutrophil activation; GO:1901701 cellular response to oxygen-containing compound; GO:0008219 cell death; GO:0071495 cellular response to endogenous stimulus; GO:0019752 carboxylic acid metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0009725 response to hormone; GO:0009056 catabolic process; ","GO:0034774 secretory granule lumen; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0043209 myelin sheath; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0005929 cilium; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0031012 extracellular matrix; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0030955 potassium ion binding; GO:0005515 protein binding; GO:0003823 antigen binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0016301 kinase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0023023 MHC protein complex binding; GO:0032550 purine ribonucleoside binding; GO:0023026 MHC class II protein complex binding; GO:0045296 cadherin binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0031420 alkali metal ion binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0000287 magnesium ion binding; GO:0003723 RNA binding; GO:0004743 pyruvate kinase activity; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0044877 macromolecular complex binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0050839 cell adhesion molecule binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003676 nucleic acid binding; GO:0046872 metal ion binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0032403 protein complex binding; ","K00873","PK; pyruvate kinase [EC:2.7.1.40]","hsa00620 Pyruvate metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa04922 Glucagon signaling pathway - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); hsa05230 Central carbon metabolism in cancer - Homo sapiens (human); hsa05203 Viral carcinogenesis - Homo sapiens (human); hsa00230 Purine metabolism - Homo sapiens (human); hsa04930 Type II diabetes mellitus - Homo sapiens (human); hsa01230 Biosynthesis of amino acids - Homo sapiens (human); hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human); ","IPR015794; IPR015813; IPR011037; IPR015806; IPR015795; IPR015793; ","\"Pyruvate kinase, alpha/beta; Pyruvate/Phosphoenolpyruvate kinase-like domain; Pyruvate kinase-like, insert domain; Pyruvate kinase, beta-barrel insert domain; Pyruvate kinase, C-terminal; Pyruvate kinase, barrel; \"\r"]
["P14625","Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1","HSP90B1",92.468,323.31,45,39,92,37,1.006,0.997,0.988,1.008,1.012,0.986,1.005,0.633,"endoplasmic reticulum\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0010941 regulation of cell death; GO:0046683 response to organophosphorus; GO:0036503 ERAD pathway; GO:0031347 regulation of defense response; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0030036 actin cytoskeleton organization; GO:0008152 metabolic process; GO:0035966 response to topologically incorrect protein; GO:0055065 metal ion homeostasis; GO:0009719 response to endogenous stimulus; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0008104 protein localization; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0051174 regulation of phosphorus metabolic process; GO:0002758 innate immune response-activating signal transduction; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0031323 regulation of cellular metabolic process; GO:0006874 cellular calcium ion homeostasis; GO:0050776 regulation of immune response; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0010243 response to organonitrogen compound; GO:0051336 regulation of hydrolase activity; GO:0044710 single-organism metabolic process; GO:0030163 protein catabolic process; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0035304 regulation of protein dephosphorylation; GO:1901698 response to nitrogen compound; GO:0044260 cellular macromolecule metabolic process; GO:0002682 regulation of immune system process; GO:0097435 supramolecular fiber organization; GO:0060548 negative regulation of cell death; GO:0036500 ATF6-mediated unfolded protein response; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0033554 cellular response to stress; GO:0034976 response to endoplasmic reticulum stress; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:1901700 response to oxygen-containing compound; GO:0043067 regulation of programmed cell death; GO:0044267 cellular protein metabolic process; GO:0080134 regulation of response to stress; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0031349 positive regulation of defense response; GO:0014074 response to purine-containing compound; GO:0070482 response to oxygen levels; GO:0044248 cellular catabolic process; GO:0006898 receptor-mediated endocytosis; GO:0007010 cytoskeleton organization; GO:0034613 cellular protein localization; GO:0050778 positive regulation of immune response; GO:0048878 chemical homeostasis; GO:0006986 response to unfolded protein; GO:0002253 activation of immune response; GO:0032527 protein exit from endoplasmic reticulum; GO:0006950 response to stress; GO:0031247 actin rod assembly; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0071407 cellular response to organic cyclic compound; GO:0071702 organic substance transport; GO:0010033 response to organic substance; GO:0006984 ER-nucleus signaling pathway; GO:0044238 primary metabolic process; GO:0061572 actin filament bundle organization; GO:0045184 establishment of protein localization; GO:0006873 cellular ion homeostasis; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0036293 response to decreased oxygen levels; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0072503 cellular divalent inorganic cation homeostasis; GO:0044699 single-organism process; GO:0030968 endoplasmic reticulum unfolded protein response; GO:0051234 establishment of localization; GO:0006457 protein folding; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0030433 ubiquitin-dependent ERAD pathway; GO:0045088 regulation of innate immune response; GO:0022607 cellular component assembly; GO:0035303 regulation of dephosphorylation; GO:0002221 pattern recognition receptor signaling pathway; GO:0033036 macromolecule localization; GO:0070887 cellular response to chemical stimulus; GO:0030970 retrograde protein transport, ER to cytosol; GO:0050801 ion homeostasis; GO:0055074 calcium ion homeostasis; GO:0098771 inorganic ion homeostasis; GO:1903513 endoplasmic reticulum to cytosol transport; GO:0019725 cellular homeostasis; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0071318 cellular response to ATP; GO:0023052 signaling; GO:0002764 immune response-regulating signaling pathway; GO:0071417 cellular response to organonitrogen compound; GO:1902589 single-organism organelle organization; GO:0051208 sequestering of calcium ion; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0042221 response to chemical; GO:1901699 cellular response to nitrogen compound; GO:0002224 toll-like receptor signaling pathway; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0051238 sequestering of metal ion; GO:0072507 divalent inorganic cation homeostasis; GO:0016043 cellular component organization; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0002218 activation of innate immune response; GO:0044257 cellular protein catabolic process; GO:0043666 regulation of phosphoprotein phosphatase activity; GO:0043069 negative regulation of programmed cell death; GO:0035967 cellular response to topologically incorrect protein; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0030003 cellular cation homeostasis; GO:0007015 actin filament organization; GO:0034975 protein folding in endoplasmic reticulum; GO:0051017 actin filament bundle assembly; GO:0050896 response to stimulus; GO:0010498 proteasomal protein catabolic process; GO:0055082 cellular chemical homeostasis; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0055080 cation homeostasis; GO:0043066 negative regulation of apoptotic process; GO:0001666 response to hypoxia; GO:0006886 intracellular protein transport; GO:0002757 immune response-activating signal transduction; GO:0006508 proteolysis; GO:0051235 maintenance of location; GO:0009987 cellular process; GO:0043632 modification-dependent macromolecule catabolic process; GO:0033198 response to ATP; GO:0044265 cellular macromolecule catabolic process; GO:0045089 positive regulation of innate immune response; GO:0034620 cellular response to unfolded protein; GO:0010921 regulation of phosphatase activity; GO:0019941 modification-dependent protein catabolic process; GO:0044712 single-organism catabolic process; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0070727 cellular macromolecule localization; GO:1901701 cellular response to oxygen-containing compound; GO:0051246 regulation of protein metabolic process; GO:0071495 cellular response to endogenous stimulus; GO:0002684 positive regulation of immune system process; GO:0009057 macromolecule catabolic process; GO:0006875 cellular metal ion homeostasis; GO:0009056 catabolic process; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0048770 pigment granule; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005925 focal adhesion; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0030055 cell-substrate junction; GO:0030139 endocytic vesicle; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043233 organelle lumen; GO:0005924 cell-substrate adherens junction; GO:0097708 intracellular vesicle; GO:0005788 endoplasmic reticulum lumen; GO:0043229 intracellular organelle; GO:0042470 melanosome; GO:0044446 intracellular organelle part; GO:0030496 midbody; GO:0070161 anchoring junction; GO:0012505 endomembrane system; GO:0034663 endoplasmic reticulum chaperone complex; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0031012 extracellular matrix; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0044432 endoplasmic reticulum part; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0071682 endocytic vesicle lumen; ","GO:1901265 nucleoside phosphate binding; GO:0019903 protein phosphatase binding; GO:0005102 receptor binding; GO:0005515 protein binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0019902 phosphatase binding; GO:0050750 low-density lipoprotein particle receptor binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003723 RNA binding; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0032549 ribonucleoside binding; GO:0070325 lipoprotein particle receptor binding; GO:0097367 carbohydrate derivative binding; GO:0003676 nucleic acid binding; GO:0046872 metal ion binding; GO:0032555 purine ribonucleotide binding; GO:0005509 calcium ion binding; GO:0001883 purine nucleoside binding; GO:0051082 unfolded protein binding; GO:0046790 virion binding; GO:0019899 enzyme binding; GO:0036094 small molecule binding; ","K09487","HSP90B; heat shock protein 90kDa beta","hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa04657 IL-17 signaling pathway - Homo sapiens (human); hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human); hsa04918 Thyroid hormone synthesis - Homo sapiens (human); hsa05215 Prostate cancer - Homo sapiens (human); hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); hsa04915 Estrogen signaling pathway - Homo sapiens (human); ","IPR020575; IPR020568; IPR003594; ","\"Heat shock protein Hsp90, N-terminal; Ribosomal protein S5 domain 2-type fold; Histidine kinase-like ATPase, C-terminal domain; \"\r"]
["P14649","Myosin light chain 6B OS=Homo sapiens OX=9606 GN=MYL6B","MYL6B",22.764,13.209,27.4,5,12,3,1.003,1.152,1.038,0.883,0.956,0.984,0.884,0.081,"cytoplasm\r","GO:0032502 developmental process; GO:0014706 striated muscle tissue development; GO:0030048 actin filament-based movement; GO:0044707 single-multicellular organism process; GO:0030049 muscle filament sliding; GO:0070252 actin-mediated cell contraction; GO:0003012 muscle system process; GO:0009888 tissue development; GO:0003008 system process; GO:0033275 actin-myosin filament sliding; GO:0060537 muscle tissue development; GO:0048731 system development; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0060538 skeletal muscle organ development; GO:0032501 multicellular organismal process; GO:0048513 animal organ development; GO:0006936 muscle contraction; GO:0007517 muscle organ development; GO:0044767 single-organism developmental process; GO:0030029 actin filament-based process; GO:0061061 muscle structure development; GO:0006928 movement of cell or subcellular component; GO:0007275 multicellular organism development; GO:0007519 skeletal muscle tissue development; GO:0048856 anatomical structure development; GO:0009987 cellular process; ","GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0099512 supramolecular fiber; GO:0005623 cell; GO:0099080 supramolecular complex; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:0016460 myosin II complex; GO:0043292 contractile fiber; GO:1903561 extracellular vesicle; GO:0016459 myosin complex; GO:0043227 membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0005859 muscle myosin complex; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0015629 actin cytoskeleton; GO:0016461 unconventional myosin complex; GO:0099081 supramolecular polymer; GO:0043226 organelle; GO:0044449 contractile fiber part; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0003774 motor activity; GO:0043167 ion binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0017111 nucleoside-triphosphatase activity; GO:0008307 structural constituent of muscle; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005509 calcium ion binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005198 structural molecule activity; ","K12751","MYL6; myosin light chain 6","hsa04921 Oxytocin signaling pathway - Homo sapiens (human); hsa04530 Tight junction - Homo sapiens (human); hsa04270 Vascular smooth muscle contraction - Homo sapiens (human); ","IPR011992; IPR002048; ","EF-hand domain pair; EF-hand domain; \r"]
["P14735","Insulin-degrading enzyme OS=Homo sapiens OX=9606 GN=IDE","IDE",117.97,168.52,27.3,25,48,25,0.704,0.691,0.696,1.269,1.275,1.283,1.83,3.51e-08,"mitochondria\r","GO:0044409 entry into host; GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0006518 peptide metabolic process; GO:0007166 cell surface receptor signaling pathway; GO:0032459 regulation of protein oligomerization; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0065003 macromolecular complex assembly; GO:0009719 response to endogenous stimulus; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0044419 interspecies interaction between organisms; GO:1901652 response to peptide; GO:0046718 viral entry into host cell; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0051291 protein heterooligomerization; GO:1901575 organic substance catabolic process; GO:0010243 response to organonitrogen compound; GO:0032269 negative regulation of cellular protein metabolic process; GO:0030163 protein catabolic process; GO:1901698 response to nitrogen compound; GO:0032869 cellular response to insulin stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0010817 regulation of hormone levels; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0051260 protein homooligomerization; GO:0051806 entry into cell of other organism involved in symbiotic interaction; GO:0044267 cellular protein metabolic process; GO:1901700 response to oxygen-containing compound; GO:0050435 beta-amyloid metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:1901142 insulin metabolic process; GO:0051259 protein oligomerization; GO:0044248 cellular catabolic process; GO:0007275 multicellular organism development; GO:0006461 protein complex assembly; GO:0045861 negative regulation of proteolysis; GO:0042447 hormone catabolic process; GO:0030162 regulation of proteolysis; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0008340 determination of adult lifespan; GO:1901564 organonitrogen compound metabolic process; GO:0008286 insulin receptor signaling pathway; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0051130 positive regulation of cellular component organization; GO:0007165 signal transduction; GO:1901653 cellular response to peptide; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0051262 protein tetramerization; GO:0043171 peptide catabolic process; GO:0032461 positive regulation of protein oligomerization; GO:0031334 positive regulation of protein complex assembly; GO:0070887 cellular response to chemical stimulus; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0032502 developmental process; GO:0010259 multicellular organism aging; GO:0042445 hormone metabolic process; GO:0071822 protein complex subunit organization; GO:0048522 positive regulation of cellular process; GO:0019725 cellular homeostasis; GO:0043603 cellular amide metabolic process; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0071417 cellular response to organonitrogen compound; GO:0030260 entry into host cell; GO:0050789 regulation of biological process; GO:0032868 response to insulin; GO:0042221 response to chemical; GO:0043254 regulation of protein complex assembly; GO:0032268 regulation of cellular protein metabolic process; GO:0043434 response to peptide hormone; GO:1901699 cellular response to nitrogen compound; GO:0032870 cellular response to hormone stimulus; GO:0051828 entry into other organism involved in symbiotic interaction; GO:0007568 aging; GO:0019222 regulation of metabolic process; GO:0070271 protein complex biogenesis; GO:0048856 anatomical structure development; GO:0016043 cellular component organization; GO:1901143 insulin catabolic process; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0019058 viral life cycle; GO:0044087 regulation of cellular component biogenesis; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0051289 protein homotetramerization; GO:0016032 viral process; GO:0071375 cellular response to peptide hormone stimulus; GO:0006508 proteolysis; GO:0034641 cellular nitrogen compound metabolic process; GO:0010992 ubiquitin homeostasis; GO:0009987 cellular process; GO:0044265 cellular macromolecule catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0051701 interaction with host; GO:0048518 positive regulation of biological process; GO:0043933 macromolecular complex subunit organization; GO:0010815 bradykinin catabolic process; GO:1901701 cellular response to oxygen-containing compound; GO:1901565 organonitrogen compound catabolic process; GO:0071495 cellular response to endogenous stimulus; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0009057 macromolecule catabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0051128 regulation of cellular component organization; GO:0009725 response to hormone; GO:0009056 catabolic process; GO:0044089 positive regulation of cellular component biogenesis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044438 microbody part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:1905369 endopeptidase complex; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0005782 peroxisomal matrix; GO:0005622 intracellular; GO:0044464 cell part; GO:0042579 microbody; GO:0044445 cytosolic part; GO:1905368 peptidase complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0044439 peroxisomal part; GO:0000502 proteasome complex; GO:0005777 peroxisome; GO:0044446 intracellular organelle part; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0031907 microbody lumen; GO:0031597 cytosolic proteasome complex; GO:0009986 cell surface; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0031626 beta-endorphin binding; GO:0008233 peptidase activity; GO:1901265 nucleoside phosphate binding; GO:0042562 hormone binding; GO:0005102 receptor binding; GO:0046983 protein dimerization activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0032182 ubiquitin-like protein binding; GO:0016887 ATPase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0042802 identical protein binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0042277 peptide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0004222 metalloendopeptidase activity; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0043559 insulin binding; GO:0008237 metallopeptidase activity; GO:0033218 amide binding; GO:0000166 nucleotide binding; GO:0008270 zinc ion binding; GO:0017046 peptide hormone binding; GO:0017111 nucleoside-triphosphatase activity; GO:0001618 virus receptor activity; GO:0004175 endopeptidase activity; GO:0001540 beta-amyloid binding; GO:0032549 ribonucleoside binding; GO:0060089 molecular transducer activity; GO:0097367 carbohydrate derivative binding; GO:0004872 receptor activity; GO:0046914 transition metal ion binding; GO:0042803 protein homodimerization activity; GO:0043130 ubiquitin binding; GO:0046872 metal ion binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0001948 glycoprotein binding; GO:0042165 neurotransmitter binding; GO:0036094 small molecule binding; ","K01408","IDE; insulysin [EC:3.4.24.56]","hsa05010 Alzheimer's disease - Homo sapiens (human); ","IPR007863; IPR032632; IPR011765; IPR011249; IPR011237; ","\"Peptidase M16, C-terminal; Peptidase M16, middle/third domain; Peptidase M16, N-terminal; Metalloenzyme, LuxS/M16 peptidase-like; Peptidase M16 domain; \"\r"]
["P14780","Matrix metalloproteinase-9 OS=Homo sapiens OX=9606 GN=MMP9","MMP9",78.457,2.395,1.4,1,1,1,0.449,0.468,0.357,1.477,1.508,1.674,3.657,1.44E-4,"extracellular\r","GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0030335 positive regulation of cell migration; GO:0045321 leukocyte activation; GO:0032270 positive regulation of cellular protein metabolic process; GO:0007166 cell surface receptor signaling pathway; GO:0022414 reproductive process; GO:0007566 embryo implantation; GO:0010821 regulation of mitochondrion organization; GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway; GO:0007492 endoderm development; GO:0010466 negative regulation of peptidase activity; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0044706 multi-multicellular organism process; GO:0044702 single organism reproductive process; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009790 embryo development; GO:0051099 positive regulation of binding; GO:0044259 multicellular organismal macromolecule metabolic process; GO:0048598 embryonic morphogenesis; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0030574 collagen catabolic process; GO:0052548 regulation of endopeptidase activity; GO:0051051 negative regulation of transport; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0051174 regulation of phosphorus metabolic process; GO:0010632 regulation of epithelial cell migration; GO:0080090 regulation of primary metabolic process; GO:0001503 ossification; GO:0043269 regulation of ion transport; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0002520 immune system development; GO:0048870 cell motility; GO:0051272 positive regulation of cellular component movement; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0051549 positive regulation of keratinocyte migration; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0043388 positive regulation of DNA binding; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0006810 transport; GO:0034762 regulation of transmembrane transport; GO:0048513 animal organ development; GO:0050900 leukocyte migration; GO:0051336 regulation of hydrolase activity; GO:1902532 negative regulation of intracellular signal transduction; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:2001257 regulation of cation channel activity; GO:0010604 positive regulation of macromolecule metabolic process; GO:1904705 regulation of vascular smooth muscle cell proliferation; GO:0032412 regulation of ion transmembrane transporter activity; GO:0060548 negative regulation of cell death; GO:0043068 positive regulation of programmed cell death; GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0050794 regulation of cellular process; GO:0000003 reproduction; GO:0044707 single-multicellular organism process; GO:0010951 negative regulation of endopeptidase activity; GO:0002283 neutrophil activation involved in immune response; GO:0042127 regulation of cell proliferation; GO:0031399 regulation of protein modification process; GO:1904707 positive regulation of vascular smooth muscle cell proliferation; GO:0043067 regulation of programmed cell death; GO:2000147 positive regulation of cell motility; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0051239 regulation of multicellular organismal process; GO:0009653 anatomical structure morphogenesis; GO:0007565 female pregnancy; GO:0023057 negative regulation of signaling; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0010648 negative regulation of cell communication; GO:0043062 extracellular structure organization; GO:2000145 regulation of cell motility; GO:0007275 multicellular organism development; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0009966 regulation of signal transduction; GO:0032409 regulation of transporter activity; GO:1904062 regulation of cation transmembrane transport; GO:0034763 negative regulation of transmembrane transport; GO:2001267 regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway; GO:0045861 negative regulation of proteolysis; GO:1902531 regulation of intracellular signal transduction; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0030334 regulation of cell migration; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0002263 cell activation involved in immune response; GO:0034766 negative regulation of ion transmembrane transport; GO:0045055 regulated exocytosis; GO:0051247 positive regulation of protein metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0032963 collagen metabolic process; GO:0006928 movement of cell or subcellular component; GO:0001775 cell activation; GO:0048661 positive regulation of smooth muscle cell proliferation; GO:0051179 localization; GO:0006955 immune response; GO:0048584 positive regulation of response to stimulus; GO:0006887 exocytosis; GO:0008284 positive regulation of cell proliferation; GO:0090199 regulation of release of cytochrome c from mitochondria; GO:0051674 localization of cell; GO:0009968 negative regulation of signal transduction; GO:0040017 positive regulation of locomotion; GO:0032092 positive regulation of protein binding; GO:0023051 regulation of signaling; GO:0048869 cellular developmental process; GO:0044236 multicellular organism metabolic process; GO:0044699 single-organism process; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:2001233 regulation of apoptotic signaling pathway; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:2001243 negative regulation of intrinsic apoptotic signaling pathway; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0022617 extracellular matrix disassembly; GO:0030198 extracellular matrix organization; GO:2001258 negative regulation of cation channel activity; GO:0032413 negative regulation of ion transmembrane transporter activity; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:0045937 positive regulation of phosphate metabolic process; GO:0009888 tissue development; GO:2000116 regulation of cysteine-type endopeptidase activity; GO:0001704 formation of primary germ layer; GO:0002521 leukocyte differentiation; GO:0002446 neutrophil mediated immunity; GO:0051098 regulation of binding; GO:0048522 positive regulation of cellular process; GO:0022898 regulation of transmembrane transporter activity; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0010942 positive regulation of cell death; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0010638 positive regulation of organelle organization; GO:0032940 secretion by cell; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0040011 locomotion; GO:0043299 leukocyte degranulation; GO:0019220 regulation of phosphate metabolic process; GO:0090200 positive regulation of release of cytochrome c from mitochondria; GO:0052547 regulation of peptidase activity; GO:0048856 anatomical structure development; GO:0001501 skeletal system development; GO:0016477 cell migration; GO:0016043 cellular component organization; GO:0043069 negative regulation of programmed cell death; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0048660 regulation of smooth muscle cell proliferation; GO:0051547 regulation of keratinocyte migration; GO:0043065 positive regulation of apoptotic process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0051101 regulation of DNA binding; GO:0051346 negative regulation of hydrolase activity; GO:0071704 organic substance metabolic process; GO:0007369 gastrulation; GO:0043393 regulation of protein binding; GO:0030154 cell differentiation; GO:0044243 multicellular organismal catabolic process; GO:0048013 ephrin receptor signaling pathway; GO:1901184 regulation of ERBB signaling pathway; GO:0043066 negative regulation of apoptotic process; GO:0023056 positive regulation of signaling; GO:0032410 negative regulation of transporter activity; GO:2001235 positive regulation of apoptotic signaling pathway; GO:2000117 negative regulation of cysteine-type endopeptidase activity; GO:0006508 proteolysis; GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0036230 granulocyte activation; GO:0010647 positive regulation of cell communication; GO:1900120 regulation of receptor binding; GO:0009987 cellular process; GO:1901186 positive regulation of ERBB signaling pathway; GO:0043271 negative regulation of ion transport; GO:0030099 myeloid cell differentiation; GO:0001706 endoderm formation; GO:0035987 endodermal cell differentiation; GO:0051049 regulation of transport; GO:0044712 single-organism catabolic process; GO:0001932 regulation of protein phosphorylation; GO:0033043 regulation of organelle organization; GO:0031401 positive regulation of protein modification process; GO:0010634 positive regulation of epithelial cell migration; GO:0048585 negative regulation of response to stimulus; GO:0043312 neutrophil degranulation; GO:0030225 macrophage differentiation; GO:0001934 positive regulation of protein phosphorylation; GO:0048518 positive regulation of biological process; GO:0048534 hematopoietic or lymphoid organ development; GO:0030097 hemopoiesis; GO:0010822 positive regulation of mitochondrion organization; GO:0002366 leukocyte activation involved in immune response; GO:1904063 negative regulation of cation transmembrane transport; GO:0042119 neutrophil activation; GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway; GO:0034765 regulation of ion transmembrane transport; GO:1900122 positive regulation of receptor binding; GO:0002573 myeloid leukocyte differentiation; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0044703 multi-organism reproductive process; GO:2001242 regulation of intrinsic apoptotic signaling pathway; GO:0051248 negative regulation of protein metabolic process; GO:0022411 cellular component disassembly; GO:0051128 regulation of cellular component organization; GO:0042058 regulation of epidermal growth factor receptor signaling pathway; GO:0009967 positive regulation of signal transduction; GO:0040012 regulation of locomotion; GO:0009056 catabolic process; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:1904724 tertiary granule lumen; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0070820 tertiary granule; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0043226 organelle; GO:0031012 extracellular matrix; GO:0005578 proteinaceous extracellular matrix; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0004222 metalloendopeptidase activity; GO:0008233 peptidase activity; GO:0008236 serine-type peptidase activity; GO:0043167 ion binding; GO:0044877 macromolecular complex binding; GO:0008237 metallopeptidase activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0008270 zinc ion binding; GO:0004252 serine-type endopeptidase activity; GO:0004175 endopeptidase activity; GO:0042802 identical protein binding; GO:0046914 transition metal ion binding; GO:0017171 serine hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005518 collagen binding; GO:0032403 protein complex binding; ","K01403","MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]","hsa05200 Pathways in cancer - Homo sapiens (human); hsa05219 Bladder cancer - Homo sapiens (human); hsa04657 IL-17 signaling pathway - Homo sapiens (human); hsa04668 TNF signaling pathway - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa04670 Leukocyte transendothelial migration - Homo sapiens (human); hsa01522 Endocrine resistance - Homo sapiens (human); hsa05206 MicroRNAs in cancer - Homo sapiens (human); hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human); hsa05161 Hepatitis B - Homo sapiens (human); hsa05215 Prostate cancer - Homo sapiens (human); hsa04926 Relaxin signaling pathway - Homo sapiens (human); hsa04915 Estrogen signaling pathway - Homo sapiens (human); hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human); ","IPR001818; IPR002477; IPR024079; IPR033739; IPR013806; IPR000585; IPR000562; IPR006026; ","\"Peptidase M10, metallopeptidase; Peptidoglycan binding-like; Metallopeptidase, catalytic domain; Peptidase M10A, catalytic domain; Kringle-like fold; Hemopexin-like domain; Fibronectin, type II, collagen-binding; Peptidase, metallopeptidase; \"\r"]
["P14854","Cytochrome c oxidase subunit 6B1 OS=Homo sapiens OX=9606 GN=COX6B1","COX6B1",10.192,43.663,74.4,6,9,6,1.009,1.013,0.973,1.008,0.972,1.023,1.003,0.902,"extracellular\r","GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0006123 mitochondrial electron transport, cytochrome c to oxygen; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0007420 brain development; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0048857 neural nucleus development; GO:0021762 substantia nigra development; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0006753 nucleoside phosphate metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0060322 head development; GO:0044765 single-organism transport; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0030901 midbrain development; GO:0098655 cation transmembrane transport; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0006119 oxidative phosphorylation; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:0048513 animal organ development; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0007417 central nervous system development; GO:0015980 energy derivation by oxidation of organic compounds; GO:0022900 electron transport chain; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0048856 anatomical structure development; GO:0098662 inorganic cation transmembrane transport; GO:0044707 single-multicellular organism process; GO:0016310 phosphorylation; GO:0034220 ion transmembrane transport; GO:0006725 cellular aromatic compound metabolic process; GO:0042773 ATP synthesis coupled electron transport; GO:0009259 ribonucleotide metabolic process; GO:0022904 respiratory electron transport chain; GO:0071704 organic substance metabolic process; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0006812 cation transport; GO:0006139 nucleobase-containing compound metabolic process; GO:1902600 hydrogen ion transmembrane transport; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009119 ribonucleoside metabolic process; GO:0009987 cellular process; GO:0046034 ATP metabolic process; GO:0098660 inorganic ion transmembrane transport; GO:0048731 system development; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0045333 cellular respiration; GO:0006163 purine nucleotide metabolic process; GO:0006818 hydrogen transport; GO:0015992 proton transport; GO:0046128 purine ribonucleoside metabolic process; GO:0055085 transmembrane transport; GO:0006793 phosphorus metabolic process; GO:0044767 single-organism developmental process; GO:0006811 ion transport; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0051179 localization; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:0015672 monovalent inorganic cation transport; GO:1901564 organonitrogen compound metabolic process; GO:0009123 nucleoside monophosphate metabolic process; ","GO:0016020 membrane; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0031090 organelle membrane; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031974 membrane-enclosed lumen; GO:0031970 organelle envelope lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0005758 mitochondrial intermembrane space; GO:0031975 envelope; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0031966 mitochondrial membrane; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; ","GO:0015075 ion transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0015077 monovalent inorganic cation transmembrane transporter activity; GO:0016676 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor; GO:0016675 oxidoreductase activity, acting on a heme group of donors; GO:0015078 hydrogen ion transmembrane transporter activity; GO:0015002 heme-copper terminal oxidase activity; GO:0016491 oxidoreductase activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0009055 electron carrier activity; GO:0004129 cytochrome-c oxidase activity; GO:0003824 catalytic activity; GO:0022890 inorganic cation transmembrane transporter activity; GO:0008324 cation transmembrane transporter activity; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; ","K02267","COX6B; cytochrome c oxidase subunit 6b","hsa04260 Cardiac muscle contraction - Homo sapiens (human); hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); "]
["P14866","Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL","HNRNPL",64.132,114.68,23.6,12,23,11,0.962,0.932,0.988,1.053,1.031,1.051,1.088,0.0097,"nucleus\r","GO:1905216 positive regulation of RNA binding; GO:0032270 positive regulation of cellular protein metabolic process; GO:0000381 regulation of alternative mRNA splicing, via spliceosome; GO:0010608 posttranscriptional regulation of gene expression; GO:0009891 positive regulation of biosynthetic process; GO:0050686 negative regulation of mRNA processing; GO:0051253 negative regulation of RNA metabolic process; GO:1903312 negative regulation of mRNA metabolic process; GO:0044237 cellular metabolic process; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0044093 positive regulation of molecular function; GO:0009719 response to endogenous stimulus; GO:0043170 macromolecule metabolic process; GO:1901652 response to peptide; GO:0051099 positive regulation of binding; GO:0048024 regulation of mRNA splicing, via spliceosome; GO:0006396 RNA processing; GO:0010468 regulation of gene expression; GO:0051716 cellular response to stimulus; GO:0031326 regulation of cellular biosynthetic process; GO:0045727 positive regulation of translation; GO:0080090 regulation of primary metabolic process; GO:0051098 regulation of binding; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0050684 regulation of mRNA processing; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0007623 circadian rhythm; GO:0006397 mRNA processing; GO:1902415 regulation of mRNA binding; GO:0016070 RNA metabolic process; GO:0010243 response to organonitrogen compound; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:1901698 response to nitrogen compound; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0033119 negative regulation of RNA splicing; GO:0065009 regulation of molecular function; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0016071 mRNA metabolic process; GO:1905214 regulation of RNA binding; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0034198 cellular response to amino acid starvation; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0009267 cellular response to starvation; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:1901700 response to oxygen-containing compound; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:1902416 positive regulation of mRNA binding; GO:0031669 cellular response to nutrient levels; GO:0071704 organic substance metabolic process; GO:0009991 response to extracellular stimulus; GO:0000398 mRNA splicing, via spliceosome; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0006950 response to stress; GO:0010629 negative regulation of gene expression; GO:0006807 nitrogen compound metabolic process; GO:0071496 cellular response to external stimulus; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0031668 cellular response to extracellular stimulus; GO:0034248 regulation of cellular amide metabolic process; GO:0043484 regulation of RNA splicing; GO:1903311 regulation of mRNA metabolic process; GO:0051247 positive regulation of protein metabolic process; GO:0048511 rhythmic process; GO:0051246 regulation of protein metabolic process; GO:0006417 regulation of translation; GO:0031325 positive regulation of cellular metabolic process; GO:0034250 positive regulation of cellular amide metabolic process; GO:0010467 gene expression; GO:0042594 response to starvation; GO:0031667 response to nutrient levels; GO:0031328 positive regulation of cellular biosynthetic process; GO:0048025 negative regulation of mRNA splicing, via spliceosome; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0045120 pronucleus; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0035770 ribonucleoprotein granule; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0003677 DNA binding; GO:0003723 RNA binding; GO:1901265 nucleoside phosphate binding; GO:0097157 pre-mRNA intronic binding; GO:0003730 mRNA 3'-UTR binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0000975 regulatory region DNA binding; GO:0003729 mRNA binding; GO:0001067 regulatory region nucleic acid binding; GO:1990715 mRNA CDS binding; GO:0044212 transcription regulatory region DNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0036002 pre-mRNA binding; GO:0036094 small molecule binding; ","K13159",null,null,"IPR000504; IPR012677; ","RNA recognition motif domain; Nucleotide-binding alpha-beta plait domain; \r"]
["P14868","Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS","DARS",57.136,61.318,38.3,16,23,16,0.913,0.917,0.94,1.051,1.096,1.058,1.157,0.000779,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0016043 cellular component organization; GO:0006518 peptide metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0006422 aspartyl-tRNA aminoacylation; GO:0009058 biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0043039 tRNA aminoacylation; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0046483 heterocycle metabolic process; GO:0022607 cellular component assembly; GO:0006139 nucleobase-containing compound metabolic process; GO:0065003 macromolecular complex assembly; GO:0034641 cellular nitrogen compound metabolic process; GO:0006418 tRNA aminoacylation for protein translation; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0006412 translation; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0071822 protein complex subunit organization; GO:0043043 peptide biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0016070 RNA metabolic process; GO:0006399 tRNA metabolic process; GO:0090304 nucleic acid metabolic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0044710 single-organism metabolic process; GO:0043038 amino acid activation; GO:0019752 carboxylic acid metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0070271 protein complex biogenesis; GO:0006082 organic acid metabolic process; GO:0034660 ncRNA metabolic process; GO:0043436 oxoacid metabolic process; GO:0071840 cellular component organization or biogenesis; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds; GO:1901265 nucleoside phosphate binding; GO:0016875 ligase activity, forming carbon-oxygen bonds; GO:0016874 ligase activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; GO:0004812 aminoacyl-tRNA ligase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003723 RNA binding; GO:0005524 ATP binding; GO:0004815 aspartate-tRNA ligase activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0004046 aminoacylase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003676 nucleic acid binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; GO:0036094 small molecule binding; ","K01876","aspS; aspartyl-tRNA synthetase [EC:6.1.1.12]","hsa00970 Aminoacyl-tRNA biosynthesis - Homo sapiens (human); ","IPR004364; IPR012340; IPR004365; IPR006195; ","\"Aminoacyl-tRNA synthetase, class II (D/K/N); Nucleic acid-binding, OB-fold; OB-fold nucleic acid binding domain, AA-tRNA synthetase-type; Aminoacyl-tRNA synthetase, class II; \"\r"]
["P14923","Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP","JUP",81.744,323.31,49.4,29,74,25,0.946,0.959,0.974,1.047,1.032,1.044,1.085,0.00102,"cytoplasm\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0031424 keratinization; GO:1903533 regulation of protein targeting; GO:0071603 endothelial cell-cell adhesion; GO:0090002 establishment of protein localization to plasma membrane; GO:0009605 response to external stimulus; GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication; GO:0061337 cardiac conduction; GO:0022610 biological adhesion; GO:0009913 epidermal cell differentiation; GO:0098900 regulation of action potential; GO:0065003 macromolecular complex assembly; GO:0032879 regulation of localization; GO:0051606 detection of stimulus; GO:0044093 positive regulation of molecular function; GO:0090263 positive regulation of canonical Wnt signaling pathway; GO:1903115 regulation of actin filament-based movement; GO:0034332 adherens junction organization; GO:0009719 response to endogenous stimulus; GO:0071681 cellular response to indole-3-methanol; GO:0044057 regulation of system process; GO:0007155 cell adhesion; GO:0008544 epidermis development; GO:0051651 maintenance of location in cell; GO:0008104 protein localization; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0043588 skin development; GO:0032507 maintenance of protein location in cell; GO:0072657 protein localization to membrane; GO:0080090 regulation of primary metabolic process; GO:0070268 cornification; GO:0044763 single-organism cellular process; GO:0060828 regulation of canonical Wnt signaling pathway; GO:0048870 cell motility; GO:0097306 cellular response to alcohol; GO:0007009 plasma membrane organization; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:0051291 protein heterooligomerization; GO:1903506 regulation of nucleic acid-templated transcription; GO:0010243 response to organonitrogen compound; GO:0048513 animal organ development; GO:0051090 regulation of sequence-specific DNA binding transcription factor activity; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0098602 single organism cell adhesion; GO:0051223 regulation of protein transport; GO:0050982 detection of mechanical stimulus; GO:0042307 positive regulation of protein import into nucleus; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0030855 epithelial cell differentiation; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0002283 neutrophil activation involved in immune response; GO:0042127 regulation of cell proliferation; GO:0007016 cytoskeletal anchoring at plasma membrane; GO:0009581 detection of external stimulus; GO:0009628 response to abiotic stimulus; GO:1901700 response to oxygen-containing compound; GO:0086042 cardiac muscle cell-cardiac muscle cell adhesion; GO:0034109 homotypic cell-cell adhesion; GO:0051239 regulation of multicellular organismal process; GO:1990778 protein localization to cell periphery; GO:0060341 regulation of cellular localization; GO:0051259 protein oligomerization; GO:0090136 epithelial cell-cell adhesion; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902580 single-organism cellular localization; GO:0032880 regulation of protein localization; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0034613 cellular protein localization; GO:0009966 regulation of signal transduction; GO:0090150 establishment of protein localization to membrane; GO:0006461 protein complex assembly; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0009582 detection of abiotic stimulus; GO:0002376 immune system process; GO:0032970 regulation of actin filament-based process; GO:0071407 cellular response to organic cyclic compound; GO:0097305 response to alcohol; GO:0010033 response to organic substance; GO:0002263 cell activation involved in immune response; GO:0045184 establishment of protein localization; GO:1900182 positive regulation of protein localization to nucleus; GO:0045055 regulated exocytosis; GO:0072659 protein localization to plasma membrane; GO:0046822 regulation of nucleocytoplasmic transport; GO:1904951 positive regulation of establishment of protein localization; GO:0030111 regulation of Wnt signaling pathway; GO:0006996 organelle organization; GO:0002027 regulation of heart rate; GO:0061024 membrane organization; GO:0030177 positive regulation of Wnt signaling pathway; GO:0001775 cell activation; GO:0006928 movement of cell or subcellular component; GO:0012501 programmed cell death; GO:0006955 immune response; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:1903827 regulation of cellular protein localization; GO:1904591 positive regulation of protein import; GO:0006887 exocytosis; GO:0010256 endomembrane system organization; GO:0051674 localization of cell; GO:0086069 bundle of His cell to Purkinje myocyte communication; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:0045216 cell-cell junction organization; GO:0044699 single-organism process; GO:0002159 desmosome assembly; GO:0034113 heterotypic cell-cell adhesion; GO:0051234 establishment of localization; GO:0098901 regulation of cardiac muscle cell action potential; GO:2001141 regulation of RNA biosynthetic process; GO:0042306 regulation of protein import into nucleus; GO:0016337 single organismal cell-cell adhesion; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0055117 regulation of cardiac muscle contraction; GO:0046824 positive regulation of nucleocytoplasmic transport; GO:0033036 macromolecule localization; GO:0070887 cellular response to chemical stimulus; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0060429 epithelium development; GO:0098911 regulation of ventricular cardiac muscle cell action potential; GO:0071822 protein complex subunit organization; GO:0030216 keratinocyte differentiation; GO:0009888 tissue development; GO:0031326 regulation of cellular biosynthetic process; GO:0002934 desmosome organization; GO:0002446 neutrophil mediated immunity; GO:0098609 cell-cell adhesion; GO:0035637 multicellular organismal signaling; GO:0048522 positive regulation of cellular process; GO:0032386 regulation of intracellular transport; GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity; GO:0090257 regulation of muscle system process; GO:0023052 signaling; GO:0002444 myeloid leukocyte mediated immunity; GO:0006942 regulation of striated muscle contraction; GO:0051050 positive regulation of transport; GO:0042391 regulation of membrane potential; GO:0071417 cellular response to organonitrogen compound; GO:1902589 single-organism organelle organization; GO:0071680 response to indole-3-methanol; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:1901699 cellular response to nitrogen compound; GO:0032940 secretion by cell; GO:1900180 regulation of protein localization to nucleus; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0034333 adherens junction assembly; GO:0043299 leukocyte degranulation; GO:0040011 locomotion; GO:0070271 protein complex biogenesis; GO:0048856 anatomical structure development; GO:0051222 positive regulation of protein transport; GO:0016477 cell migration; GO:0034329 cell junction assembly; GO:0016043 cellular component organization; GO:0090316 positive regulation of intracellular protein transport; GO:0002252 immune effector process; GO:1903829 positive regulation of cellular protein localization; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:1903522 regulation of blood circulation; GO:0071310 cellular response to organic substance; GO:1904589 regulation of protein import; GO:0008016 regulation of heart contraction; GO:0050896 response to stimulus; GO:0070201 regulation of establishment of protein localization; GO:0086004 regulation of cardiac muscle cell contraction; GO:0009612 response to mechanical stimulus; GO:0030154 cell differentiation; GO:0086091 regulation of heart rate by cardiac conduction; GO:0023056 positive regulation of signaling; GO:0036230 granulocyte activation; GO:0051235 maintenance of location; GO:0010647 positive regulation of cell communication; GO:0033157 regulation of intracellular protein transport; GO:0009987 cellular process; GO:0007043 cell-cell junction assembly; GO:0006355 regulation of transcription, DNA-templated; GO:0045185 maintenance of protein location; GO:0051049 regulation of transport; GO:0032388 positive regulation of intracellular transport; GO:0006937 regulation of muscle contraction; GO:0044802 single-organism membrane organization; GO:0010556 regulation of macromolecule biosynthetic process; GO:0043312 neutrophil degranulation; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0043933 macromolecular complex subunit organization; GO:0051641 cellular localization; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0070727 cellular macromolecule localization; GO:1901701 cellular response to oxygen-containing compound; GO:0034330 cell junction organization; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0071495 cellular response to endogenous stimulus; GO:0009967 positive regulation of signal transduction; GO:0071840 cellular component organization or biogenesis; GO:0086065 cell communication involved in cardiac conduction; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0019898 extrinsic component of membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0005913 cell-cell adherens junction; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0031674 I band; GO:0009898 cytoplasmic side of plasma membrane; GO:1904813 ficolin-1-rich granule lumen; GO:0014704 intercalated disc; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0098590 plasma membrane region; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0098552 side of membrane; GO:0099513 polymeric cytoskeletal fiber; GO:0044430 cytoskeletal part; GO:0098797 plasma membrane protein complex; GO:0019897 extrinsic component of plasma membrane; GO:0070161 anchoring junction; GO:0005576 extracellular region; GO:0016328 lateral plasma membrane; GO:0099081 supramolecular polymer; GO:0005886 plasma membrane; GO:0030057 desmosome; GO:0043231 intracellular membrane-bounded organelle; GO:0031012 extracellular matrix; GO:0045111 intermediate filament cytoskeleton; GO:0005915 zonula adherens; GO:0005882 intermediate filament; GO:0044449 contractile fiber part; GO:0016342 catenin complex; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0034774 secretory granule lumen; GO:0031410 cytoplasmic vesicle; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0044291 cell-cell contact zone; GO:0098796 membrane protein complex; GO:0030016 myofibril; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0099512 supramolecular fiber; GO:0030018 Z disc; GO:0005911 cell-cell junction; GO:0098562 cytoplasmic side of membrane; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0031983 vesicle lumen; GO:0016327 apicolateral plasma membrane; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0044425 membrane part; GO:0071665 gamma-catenin-TCF7L2 complex; GO:0043292 contractile fiber; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0005916 fascia adherens; GO:0030141 secretory granule; GO:0032993 protein-DNA complex; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0071664 catenin-TCF7L2 complex; GO:0005829 cytosol; GO:0015629 actin cytoskeleton; GO:0043296 apical junction complex; GO:0043226 organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0044459 plasma membrane part; GO:0035580 specific granule lumen; GO:0001533 cornified envelope; GO:0042581 specific granule; GO:0030017 sarcomere; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005199 structural constituent of cell wall; GO:0019903 protein phosphatase binding; GO:0019901 protein kinase binding; GO:0046983 protein dimerization activity; GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication; GO:0005515 protein binding; GO:0003712 transcription cofactor activity; GO:0098632 protein binding involved in cell-cell adhesion; GO:0019900 kinase binding; GO:0045294 alpha-catenin binding; GO:0004871 signal transducer activity; GO:0086080 protein binding involved in heterotypic cell-cell adhesion; GO:0050839 cell adhesion molecule binding; GO:0042802 identical protein binding; GO:0098631 protein binding involved in cell adhesion; GO:0005488 binding; GO:0042803 protein homodimerization activity; GO:0045296 cadherin binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0003713 transcription coactivator activity; GO:0019902 phosphatase binding; GO:0000988 transcription factor activity, protein binding; GO:0005198 structural molecule activity; GO:0019899 enzyme binding; ","K10056","JUP; junction plakoglobin","hsa05200 Pathways in cancer - Homo sapiens (human); hsa05221 Acute myeloid leukemia - Homo sapiens (human); hsa05226 Gastric cancer - Homo sapiens (human); hsa05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human); hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human); ","IPR011989; IPR016024; ","Armadillo-like helical; Armadillo-type fold; \r"]
["P14927","Cytochrome b-c1 complex subunit 7 OS=Homo sapiens OX=9606 GN=UQCRB","UQCRB",13.53,39.733,40.5,5,8,5,1.031,1.016,1.062,0.935,0.978,0.981,0.931,0.024,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0034551 mitochondrial respiratory chain complex III assembly; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0006753 nucleoside phosphate metabolic process; GO:0007005 mitochondrion organization; GO:0019693 ribose phosphate metabolic process; GO:0044765 single-organism transport; GO:0071822 protein complex subunit organization; GO:0098655 cation transmembrane transport; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0006119 oxidative phosphorylation; GO:0044763 single-organism cellular process; GO:0072521 purine-containing compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0006810 transport; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0022900 electron transport chain; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0070271 protein complex biogenesis; GO:0033108 mitochondrial respiratory chain complex assembly; GO:0098662 inorganic cation transmembrane transport; GO:0016043 cellular component organization; GO:0016310 phosphorylation; GO:0034220 ion transmembrane transport; GO:0017004 cytochrome complex assembly; GO:0006725 cellular aromatic compound metabolic process; GO:0042773 ATP synthesis coupled electron transport; GO:0009259 ribonucleotide metabolic process; GO:0022904 respiratory electron transport chain; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:1902578 single-organism localization; GO:0006139 nucleobase-containing compound metabolic process; GO:0006812 cation transport; GO:1901135 carbohydrate derivative metabolic process; GO:1902600 hydrogen ion transmembrane transport; GO:0034641 cellular nitrogen compound metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0009119 ribonucleoside metabolic process; GO:0006461 protein complex assembly; GO:0043623 cellular protein complex assembly; GO:0046034 ATP metabolic process; GO:0017062 respiratory chain complex III assembly; GO:0034622 cellular macromolecular complex assembly; GO:0098660 inorganic ion transmembrane transport; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0045333 cellular respiration; GO:0006163 purine nucleotide metabolic process; GO:0006818 hydrogen transport; GO:0015992 proton transport; GO:0043933 macromolecular complex subunit organization; GO:0046128 purine ribonucleoside metabolic process; GO:0055085 transmembrane transport; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0009060 aerobic respiration; GO:0006811 ion transport; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0051179 localization; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:0015672 monovalent inorganic cation transport; GO:0097033 mitochondrial respiratory chain complex III biogenesis; GO:0071840 cellular component organization or biogenesis; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0098798 mitochondrial protein complex; GO:0005623 cell; GO:0044455 mitochondrial membrane part; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:1902494 catalytic complex; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005750 mitochondrial respiratory chain complex III; GO:0019866 organelle inner membrane; GO:1990351 transporter complex; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0098803 respiratory chain complex; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0070069 cytochrome complex; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:1902495 transmembrane transporter complex; GO:0045275 respiratory chain complex III; GO:0016021 integral component of membrane; GO:0005739 mitochondrion; GO:0005746 mitochondrial respiratory chain; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:1990204 oxidoreductase complex; GO:0031975 envelope; GO:0043234 protein complex; GO:0070469 respiratory chain; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ","K00417","QCR7; ubiquinol-cytochrome c reductase subunit 7","hsa04260 Cardiac muscle contraction - Homo sapiens (human); hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); "]
["P15088","Mast cell carboxypeptidase A OS=Homo sapiens OX=9606 GN=CPA3","CPA3",48.669,37.769,24.7,12,20,12,1.226,1.139,1.171,0.841,0.849,0.817,0.709,1.44E-4,"extracellular\r","GO:0008217 regulation of blood pressure; GO:0065008 regulation of biological quality; GO:0006518 peptide metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0016486 peptide hormone processing; GO:0016485 protein processing; GO:0060177 regulation of angiotensin metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0002002 regulation of angiotensin levels in blood; GO:0008015 blood circulation; GO:0003073 regulation of systemic arterial blood pressure; GO:0034641 cellular nitrogen compound metabolic process; GO:0006508 proteolysis; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009987 cellular process; GO:0001991 regulation of systemic arterial blood pressure by circulatory renin-angiotensin; GO:0003044 regulation of systemic arterial blood pressure mediated by a chemical signal; GO:0042445 hormone metabolic process; GO:0003008 system process; GO:0001990 regulation of systemic arterial blood pressure by hormone; GO:0080090 regulation of primary metabolic process; GO:0050886 endocrine process; GO:0006807 nitrogen compound metabolic process; GO:0002003 angiotensin maturation; GO:0043603 cellular amide metabolic process; GO:0044238 primary metabolic process; GO:0032501 multicellular organismal process; GO:0050789 regulation of biological process; GO:0051246 regulation of protein metabolic process; GO:0010817 regulation of hormone levels; GO:0019222 regulation of metabolic process; GO:0010467 gene expression; GO:0051604 protein maturation; GO:0003013 circulatory system process; GO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0043226 organelle; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0030141 secretory granule; GO:0030133 transport vesicle; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0004180 carboxypeptidase activity; GO:0008233 peptidase activity; GO:0008238 exopeptidase activity; GO:0046914 transition metal ion binding; GO:0004181 metallocarboxypeptidase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0008235 metalloexopeptidase activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0016787 hydrolase activity; GO:0008237 metallopeptidase activity; GO:0008270 zinc ion binding; ","K08780","CPA3; carboxypeptidase A3 [EC:3.4.17.1]","hsa04972 Pancreatic secretion - Homo sapiens (human); hsa04974 Protein digestion and absorption - Homo sapiens (human); hsa04614 Renin-angiotensin system - Homo sapiens (human); ","IPR003146; IPR000834; IPR009020; IPR034253; ","\"Carboxypeptidase, activation peptide; Peptidase M14, carboxypeptidase A; Proteinase propeptide inhibitor; Carboxypeptidase B, carboxypeptidase domain; \"\r"]
["P15090","Fatty acid-binding protein, adipocyte OS=Homo sapiens OX=9606 GN=FABP4","FABP4",14.719,122.34,58.3,8,25,7,1.304,1.218,1.222,0.732,0.804,0.706,0.599,0.000323,"cytoplasm\r","GO:0065008 regulation of biological quality; GO:0046486 glycerolipid metabolic process; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0031347 regulation of defense response; GO:0051253 negative regulation of RNA metabolic process; GO:0071345 cellular response to cytokine stimulus; GO:0044237 cellular metabolic process; GO:0031400 negative regulation of protein modification process; GO:0051234 establishment of localization; GO:2001141 regulation of RNA biosynthetic process; GO:0046461 neutral lipid catabolic process; GO:0008152 metabolic process; GO:0033673 negative regulation of kinase activity; GO:0032103 positive regulation of response to external stimulus; GO:0006639 acylglycerol metabolic process; GO:0010035 response to inorganic substance; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0034612 response to tumor necrosis factor; GO:0050873 brown fat cell differentiation; GO:0055088 lipid homeostasis; GO:0071285 cellular response to lithium ion; GO:0070887 cellular response to chemical stimulus; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0006629 lipid metabolic process; GO:0032502 developmental process; GO:0042325 regulation of phosphorylation; GO:0010468 regulation of gene expression; GO:0051716 cellular response to stimulus; GO:0051174 regulation of phosphorus metabolic process; GO:0010226 response to lithium ion; GO:0031326 regulation of cellular biosynthetic process; GO:0034097 response to cytokine; GO:0080090 regulation of primary metabolic process; GO:0050729 positive regulation of inflammatory response; GO:0044763 single-organism cellular process; GO:0051348 negative regulation of transferase activity; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0010038 response to metal ion; GO:0006810 transport; GO:1903506 regulation of nucleic acid-templated transcription; GO:1901575 organic substance catabolic process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0044710 single-organism metabolic process; GO:1902679 negative regulation of RNA biosynthetic process; GO:0048583 regulation of response to stimulus; GO:0071241 cellular response to inorganic substance; GO:0065009 regulation of molecular function; GO:0006469 negative regulation of protein kinase activity; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0045444 fat cell differentiation; GO:0043549 regulation of kinase activity; GO:0046503 glycerolipid catabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0045859 regulation of protein kinase activity; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0071356 cellular response to tumor necrosis factor; GO:0060255 regulation of macromolecule metabolic process; GO:0031399 regulation of protein modification process; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:0050896 response to stimulus; GO:0046464 acylglycerol catabolic process; GO:0071704 organic substance metabolic process; GO:0045892 negative regulation of transcription, DNA-templated; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:0031349 positive regulation of defense response; GO:0042326 negative regulation of phosphorylation; GO:0009889 regulation of biosynthetic process; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0044248 cellular catabolic process; GO:0001933 negative regulation of protein phosphorylation; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0019433 triglyceride catabolic process; GO:0006638 neutral lipid metabolic process; GO:0016042 lipid catabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0050872 white fat cell differentiation; GO:0010629 negative regulation of gene expression; GO:0044712 single-organism catabolic process; GO:0001932 regulation of protein phosphorylation; GO:0010556 regulation of macromolecule biosynthetic process; GO:0032101 regulation of response to external stimulus; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0042632 cholesterol homeostasis; GO:0009892 negative regulation of metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0009890 negative regulation of biosynthetic process; GO:0006641 triglyceride metabolic process; GO:0051246 regulation of protein metabolic process; GO:0001816 cytokine production; GO:0044767 single-organism developmental process; GO:0010563 negative regulation of phosphorus metabolic process; GO:0050727 regulation of inflammatory response; GO:0055092 sterol homeostasis; GO:0051248 negative regulation of protein metabolic process; GO:0044242 cellular lipid catabolic process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0071248 cellular response to metal ion; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0009056 catabolic process; GO:0045936 negative regulation of phosphate metabolic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043228 non-membrane-bounded organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0005811 lipid particle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0031406 carboxylic acid binding; GO:0005488 binding; GO:0043167 ion binding; GO:0008289 lipid binding; GO:0043177 organic acid binding; GO:0043168 anion binding; GO:0005504 fatty acid binding; GO:0033293 monocarboxylic acid binding; GO:0005215 transporter activity; GO:0036094 small molecule binding; ","K08753","FABP4; fatty acid-binding protein 4, adipocyte","hsa04923 Regulation of lipolysis in adipocytes - Homo sapiens (human); hsa03320 PPAR signaling pathway - Homo sapiens (human); ","IPR000463; IPR000566; IPR012674; IPR011038; ","Cytosolic fatty-acid binding; Lipocalin/cytosolic fatty-acid binding domain; Calycin; Calycin-like; \r"]
["P15104","Glutamine synthetase OS=Homo sapiens OX=9606 GN=GLUL","GLUL",42.064,8.4645,11,5,8,5,0.747,0.757,0.801,1.206,1.169,1.275,1.584,0.000159,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0050796 regulation of insulin secretion; GO:0019740 nitrogen utilization; GO:0002793 positive regulation of peptide secretion; GO:0009749 response to glucose; GO:0044237 cellular metabolic process; GO:0009084 glutamine family amino acid biosynthetic process; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0050678 regulation of epithelial cell proliferation; GO:0032879 regulation of localization; GO:0065003 macromolecular complex assembly; GO:1901607 alpha-amino acid biosynthetic process; GO:0009743 response to carbohydrate; GO:0044765 single-organism transport; GO:0051716 cellular response to stimulus; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0098657 import into cell; GO:0006810 transport; GO:0046395 carboxylic acid catabolic process; GO:1901575 organic substance catabolic process; GO:0046883 regulation of hormone secretion; GO:0044710 single-organism metabolic process; GO:0034284 response to monosaccharide; GO:0050714 positive regulation of protein secretion; GO:0010817 regulation of hormone levels; GO:0051223 regulation of protein transport; GO:0009063 cellular amino acid catabolic process; GO:0043436 oxoacid metabolic process; GO:0051047 positive regulation of secretion; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0009267 cellular response to starvation; GO:0042127 regulation of cell proliferation; GO:0051260 protein homooligomerization; GO:0006541 glutamine metabolic process; GO:1901700 response to oxygen-containing compound; GO:0051968 positive regulation of synaptic transmission, glutamatergic; GO:0090277 positive regulation of peptide hormone secretion; GO:0051259 protein oligomerization; GO:0043649 dicarboxylic acid catabolic process; GO:1902578 single-organism localization; GO:0044248 cellular catabolic process; GO:0032880 regulation of protein localization; GO:0006461 protein complex assembly; GO:0090087 regulation of peptide transport; GO:0008652 cellular amino acid biosynthetic process; GO:0044711 single-organism biosynthetic process; GO:0006950 response to stress; GO:0050804 modulation of synaptic transmission; GO:0008283 cell proliferation; GO:0071496 cellular response to external stimulus; GO:0010033 response to organic substance; GO:1901605 alpha-amino acid metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0031668 cellular response to extracellular stimulus; GO:1904951 positive regulation of establishment of protein localization; GO:0046887 positive regulation of hormone secretion; GO:0044283 small molecule biosynthetic process; GO:0016054 organic acid catabolic process; GO:0051179 localization; GO:0008284 positive regulation of cell proliferation; GO:1901564 organonitrogen compound metabolic process; GO:1901606 alpha-amino acid catabolic process; GO:0001505 regulation of neurotransmitter levels; GO:0009746 response to hexose; GO:0016053 organic acid biosynthetic process; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0051046 regulation of secretion; GO:0009058 biosynthetic process; GO:0051234 establishment of localization; GO:0050806 positive regulation of synaptic transmission; GO:0051966 regulation of synaptic transmission, glutamatergic; GO:0010646 regulation of cell communication; GO:0006520 cellular amino acid metabolic process; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0071822 protein complex subunit organization; GO:0048522 positive regulation of cellular process; GO:1903530 regulation of secretion by cell; GO:0051050 positive regulation of transport; GO:0046394 carboxylic acid biosynthetic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:1903532 positive regulation of secretion by cell; GO:0009065 glutamine family amino acid catabolic process; GO:0070271 protein complex biogenesis; GO:0006082 organic acid metabolic process; GO:0051222 positive regulation of protein transport; GO:0043648 dicarboxylic acid metabolic process; GO:0016043 cellular component organization; GO:0006538 glutamate catabolic process; GO:0050896 response to stimulus; GO:1901566 organonitrogen compound biosynthetic process; GO:0031669 cellular response to nutrient levels; GO:0070201 regulation of establishment of protein localization; GO:0071704 organic substance metabolic process; GO:0009991 response to extracellular stimulus; GO:0002791 regulation of peptide secretion; GO:0023056 positive regulation of signaling; GO:0006536 glutamate metabolic process; GO:0010647 positive regulation of cell communication; GO:0050708 regulation of protein secretion; GO:0009987 cellular process; GO:0009064 glutamine family amino acid metabolic process; GO:0032024 positive regulation of insulin secretion; GO:0006542 glutamine biosynthetic process; GO:0044712 single-organism catabolic process; GO:0051049 regulation of transport; GO:0006807 nitrogen compound metabolic process; GO:0044282 small molecule catabolic process; GO:0048518 positive regulation of biological process; GO:0001504 neurotransmitter uptake; GO:0044249 cellular biosynthetic process; GO:0019676 ammonia assimilation cycle; GO:0043933 macromolecular complex subunit organization; GO:1901565 organonitrogen compound catabolic process; GO:0019752 carboxylic acid metabolic process; GO:0090276 regulation of peptide hormone secretion; GO:0042594 response to starvation; GO:0031667 response to nutrient levels; GO:0009056 catabolic process; GO:0006836 neurotransmitter transport; GO:0050679 positive regulation of epithelial cell proliferation; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0005783 endoplasmic reticulum; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0043025 neuronal cell body; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0043679 axon terminus; GO:0097386 glial cell projection; GO:0070062 extracellular exosome; GO:0043209 myelin sheath; GO:0005622 intracellular; GO:0044464 cell part; GO:0098793 presynapse; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0044306 neuron projection terminus; GO:0097458 neuron part; GO:0044456 synapse part; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0005791 rough endoplasmic reticulum; GO:0012505 endomembrane system; GO:0044463 cell projection part; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0045202 synapse; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0036477 somatodendritic compartment; GO:0005634 nucleus; GO:0043204 perikaryon; GO:0044297 cell body; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016597 amino acid binding; GO:0004356 glutamate-ammonia ligase activity; GO:1901265 nucleoside phosphate binding; GO:0016874 ligase activity; GO:0016211 ammonia ligase activity; GO:0005515 protein binding; GO:0045503 dynein light chain binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0031406 carboxylic acid binding; GO:0042802 identical protein binding; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0016830 carbon-carbon lyase activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0016831 carboxy-lyase activity; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0000287 magnesium ion binding; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0043177 organic acid binding; GO:0016829 lyase activity; GO:0000166 nucleotide binding; GO:0030145 manganese ion binding; GO:0016879 ligase activity, forming carbon-nitrogen bonds; GO:0004351 glutamate decarboxylase activity; GO:0032549 ribonucleoside binding; GO:0016880 acid-ammonia (or amide) ligase activity; GO:0097367 carbohydrate derivative binding; GO:0046914 transition metal ion binding; GO:0016595 glutamate binding; GO:0046872 metal ion binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; ","K01915","glnA; glutamine synthetase [EC:6.3.1.2]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa04727 GABAergic synapse - Homo sapiens (human); hsa04217 Necroptosis - Homo sapiens (human); hsa00630 Glyoxylate and dicarboxylate metabolism - Homo sapiens (human); hsa00220 Arginine biosynthesis - Homo sapiens (human); hsa00910 Nitrogen metabolism - Homo sapiens (human); hsa04724 Glutamatergic synapse - Homo sapiens (human); hsa01230 Biosynthesis of amino acids - Homo sapiens (human); hsa00250 Alanine, aspartate and glutamate metabolism - Homo sapiens (human); ","IPR008146; IPR008147; IPR014746; ","\"Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain; Glutamine synthetase/guanido kinase, catalytic domain; \"\r"]
["P15121","Aldose reductase OS=Homo sapiens OX=9606 GN=AKR1B1","AKR1B1",35.853,34.591,28.5,9,14,9,1.061,1.102,1.042,0.994,0.884,0.928,0.876,0.024,"cytoplasm\r","GO:0042446 hormone biosynthetic process; GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0010941 regulation of cell death; GO:0022414 reproductive process; GO:0006066 alcohol metabolic process; GO:0030638 polyketide metabolic process; GO:0044237 cellular metabolic process; GO:0008610 lipid biosynthetic process; GO:0008152 metabolic process; GO:0044262 cellular carbohydrate metabolic process; GO:0042180 cellular ketone metabolic process; GO:0044706 multi-multicellular organism process; GO:0044702 single organism reproductive process; GO:0009719 response to endogenous stimulus; GO:0034637 cellular carbohydrate biosynthetic process; GO:1901652 response to peptide; GO:0018931 naphthalene metabolic process; GO:0051716 cellular response to stimulus; GO:1901661 quinone metabolic process; GO:0044281 small molecule metabolic process; GO:0000302 response to reactive oxygen species; GO:0008202 steroid metabolic process; GO:0046427 positive regulation of JAK-STAT cascade; GO:0044763 single-organism cellular process; GO:1901617 organic hydroxy compound biosynthetic process; GO:0009712 catechol-containing compound metabolic process; GO:0005975 carbohydrate metabolic process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0034754 cellular hormone metabolic process; GO:0048513 animal organ development; GO:0010243 response to organonitrogen compound; GO:0006000 fructose metabolic process; GO:0030104 water homeostasis; GO:0044710 single-organism metabolic process; GO:0018958 phenol-containing compound metabolic process; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0010817 regulation of hormone levels; GO:0060548 negative regulation of cell death; GO:0048609 multicellular organismal reproductive process; GO:0046370 fructose biosynthetic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0000003 reproduction; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0033554 cellular response to stress; GO:0060135 maternal process involved in female pregnancy; GO:0042127 regulation of cell proliferation; GO:1901615 organic hydroxy compound metabolic process; GO:0009628 response to abiotic stimulus; GO:0043067 regulation of programmed cell death; GO:1901700 response to oxygen-containing compound; GO:0097164 ammonium ion metabolic process; GO:0046364 monosaccharide biosynthetic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0008207 C21-steroid hormone metabolic process; GO:0060249 anatomical structure homeostasis; GO:0007565 female pregnancy; GO:1901135 carbohydrate derivative metabolic process; GO:0007275 multicellular organism development; GO:0016137 glycoside metabolic process; GO:0009966 regulation of signal transduction; GO:0048878 chemical homeostasis; GO:1904892 regulation of STAT cascade; GO:0001822 kidney development; GO:1901655 cellular response to ketone; GO:1902531 regulation of intracellular signal transduction; GO:0044711 single-organism biosynthetic process; GO:0006950 response to stress; GO:0048731 system development; GO:0044597 daunorubicin metabolic process; GO:0003014 renal system process; GO:0046165 alcohol biosynthetic process; GO:0030647 aminoglycoside antibiotic metabolic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0019751 polyol metabolic process; GO:0006694 steroid biosynthetic process; GO:0097238 cellular response to methylglyoxal; GO:0050891 multicellular organismal water homeostasis; GO:0042542 response to hydrogen peroxide; GO:0044283 small molecule biosynthetic process; GO:0006700 C21-steroid hormone biosynthetic process; GO:0048661 positive regulation of smooth muscle cell proliferation; GO:0048584 positive regulation of response to stimulus; GO:0090420 naphthalene-containing compound metabolic process; GO:0072061 inner medullary collecting duct development; GO:0019318 hexose metabolic process; GO:0008284 positive regulation of cell proliferation; GO:1901564 organonitrogen compound metabolic process; GO:0001101 response to acid chemical; GO:0019319 hexose biosynthetic process; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0042415 norepinephrine metabolic process; GO:0031098 stress-activated protein kinase signaling cascade; GO:0048871 multicellular organismal homeostasis; GO:1904894 positive regulation of STAT cascade; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:1901653 cellular response to peptide; GO:0009415 response to water; GO:0051595 response to methylglyoxal; GO:0006979 response to oxidative stress; GO:0097066 response to thyroid hormone; GO:0034599 cellular response to oxidative stress; GO:0010035 response to inorganic substance; GO:0072044 collecting duct development; GO:0070887 cellular response to chemical stimulus; GO:0006629 lipid metabolic process; GO:0003091 renal water homeostasis; GO:0019748 secondary metabolic process; GO:0032502 developmental process; GO:0035295 tube development; GO:0042445 hormone metabolic process; GO:0034614 cellular response to reactive oxygen species; GO:0009414 response to water deprivation; GO:0019401 alditol biosynthetic process; GO:0055114 oxidation-reduction process; GO:0006059 hexitol metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0006584 catecholamine metabolic process; GO:0051186 cofactor metabolic process; GO:0071417 cellular response to organonitrogen compound; GO:0044723 single-organism carbohydrate metabolic process; GO:0001655 urogenital system development; GO:0035809 regulation of urine volume; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0006061 sorbitol biosynthetic process; GO:1901699 cellular response to nitrogen compound; GO:0001894 tissue homeostasis; GO:1901657 glycosyl compound metabolic process; GO:0019406 hexitol biosynthetic process; GO:0048856 anatomical structure development; GO:0006060 sorbitol metabolic process; GO:0046425 regulation of JAK-STAT cascade; GO:0016051 carbohydrate biosynthetic process; GO:0043069 negative regulation of programmed cell death; GO:0006725 cellular aromatic compound metabolic process; GO:0048660 regulation of smooth muscle cell proliferation; GO:0071310 cellular response to organic substance; GO:0072001 renal system development; GO:0050896 response to stimulus; GO:0070301 cellular response to hydrogen peroxide; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0043066 negative regulation of apoptotic process; GO:0023056 positive regulation of signaling; GO:0005996 monosaccharide metabolic process; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:0019400 alditol metabolic process; GO:0050878 regulation of body fluid levels; GO:0003008 system process; GO:0035556 intracellular signal transduction; GO:0006807 nitrogen compound metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0032504 multicellular organism reproduction; GO:0044598 doxorubicin metabolic process; GO:1901701 cellular response to oxygen-containing compound; GO:0071495 cellular response to endogenous stimulus; GO:0044767 single-organism developmental process; GO:0044703 multi-organism reproductive process; GO:0046173 polyol biosynthetic process; GO:0009967 positive regulation of signal transduction; GO:0009725 response to hormone; GO:0042981 regulation of apoptotic process; GO:1901654 response to ketone; GO:0065007 biological regulation; ","GO:0043218 compact myelin; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0030054 cell junction; GO:0031982 vesicle; GO:0099568 cytoplasmic region; GO:0005737 cytoplasm; GO:0032838 cell projection cytoplasm; GO:0044424 intracellular part; GO:0005911 cell-cell junction; GO:0098858 actin-based cell projection; GO:0005623 cell; GO:0097386 glial cell projection; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0097454 Schwann cell microvillus; GO:0070013 intracellular organelle lumen; GO:0043209 myelin sheath; GO:0005622 intracellular; GO:0044464 cell part; GO:0005764 lysosome; GO:0043220 Schmidt-Lanterman incisure; GO:0042629 mast cell granule; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0005576 extracellular region; GO:0033010 paranodal junction; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005902 microvillus; GO:0005773 vacuole; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0009055 electron carrier activity; GO:0016614 oxidoreductase activity, acting on CH-OH group of donors; GO:0004032 alditol:NADP+ 1-oxidoreductase activity; GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; GO:0003824 catalytic activity; GO:0008106 alcohol dehydrogenase (NADP+) activity; GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors; GO:0043795 glyceraldehyde oxidoreductase activity; GO:0004033 aldo-keto reductase (NADP) activity; GO:0016491 oxidoreductase activity; ","K00011","AKR1B; aldehyde reductase [EC:1.1.1.21]","hsa00051 Fructose and mannose metabolism - Homo sapiens (human); hsa00790 Folate biosynthesis - Homo sapiens (human); hsa00040 Pentose and glucuronate interconversions - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00052 Galactose metabolism - Homo sapiens (human); hsa00561 Glycerolipid metabolism - Homo sapiens (human); ","IPR023210; ","NADP-dependent oxidoreductase domain; \r"]
["P15144","Aminopeptidase N OS=Homo sapiens OX=9606 GN=ANPEP","ANPEP",109.54,118.53,22.4,20,32,20,1.061,1.041,1.072,0.94,0.929,0.923,0.88,2.22E-4,"endoplasmic reticulum\r","GO:0044409 entry into host; GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0006518 peptide metabolic process; GO:0001568 blood vessel development; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0001525 angiogenesis; GO:0007154 cell communication; GO:0043171 peptide catabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0048514 blood vessel morphogenesis; GO:0044419 interspecies interaction between organisms; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0046718 viral entry into host cell; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0001944 vasculature development; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0043603 cellular amide metabolic process; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0002444 myeloid leukocyte mediated immunity; GO:0051704 multi-organism process; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0030260 entry into host cell; GO:0050789 regulation of biological process; GO:0007267 cell-cell signaling; GO:0032940 secretion by cell; GO:0051828 entry into other organism involved in symbiotic interaction; GO:0043299 leukocyte degranulation; GO:0003013 circulatory system process; GO:0048856 anatomical structure development; GO:0008217 regulation of blood pressure; GO:0072359 circulatory system development; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0019058 viral life cycle; GO:0051806 entry into cell of other organism involved in symbiotic interaction; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0009653 anatomical structure morphogenesis; GO:0030154 cell differentiation; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0016032 viral process; GO:0008015 blood circulation; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0006508 proteolysis; GO:0036230 granulocyte activation; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0003008 system process; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0006807 nitrogen compound metabolic process; GO:0002376 immune system process; GO:0072358 cardiovascular system development; GO:0043312 neutrophil degranulation; GO:0044238 primary metabolic process; GO:0051701 interaction with host; GO:0002263 cell activation involved in immune response; GO:0002366 leukocyte activation involved in immune response; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:1901565 organonitrogen compound catabolic process; GO:0044767 single-organism developmental process; GO:0001775 cell activation; GO:0051179 localization; GO:0006955 immune response; GO:0009056 catabolic process; GO:0006887 exocytosis; GO:0065007 biological regulation; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0009897 external side of plasma membrane; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005765 lysosomal membrane; GO:0070062 extracellular exosome; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0098805 whole membrane; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0000323 lytic vacuole; GO:0098552 side of membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0030667 secretory granule membrane; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0005793 endoplasmic reticulum-Golgi intermediate compartment; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0009986 cell surface; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0008238 exopeptidase activity; GO:0008233 peptidase activity; GO:0043167 ion binding; GO:0070006 metalloaminopeptidase activity; GO:0008235 metalloexopeptidase activity; GO:0004177 aminopeptidase activity; GO:0008237 metallopeptidase activity; GO:0016787 hydrolase activity; GO:0033218 amide binding; GO:0008270 zinc ion binding; GO:0001618 virus receptor activity; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0042277 peptide binding; GO:0005488 binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0046872 metal ion binding; GO:0043169 cation binding; ","K11140","ANPEP; aminopeptidase N [EC:3.4.11.2]","hsa00480 Glutathione metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa04614 Renin-angiotensin system - Homo sapiens (human); hsa04640 Hematopoietic cell lineage - Homo sapiens (human); ","IPR014782; IPR024571; ","\"Peptidase M1, membrane alanine aminopeptidase, N-terminal; ERAP1-like C-terminal domain; \"\r"]
["P15153","Ras-related C3 botulinum toxin substrate 2 OS=Homo sapiens OX=9606 GN=RAC2","RAC2",21.429,2.066,29.2,6,9,1,0.899,0.855,0.865,1.181,1.138,1.056,1.289,0.00222,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0060627 regulation of vesicle-mediated transport; GO:0044700 single organism signaling; GO:0002694 regulation of leukocyte activation; GO:0030335 positive regulation of cell migration; GO:0065008 regulation of biological quality; GO:0007596 blood coagulation; GO:0032944 regulation of mononuclear cell proliferation; GO:1903955 positive regulation of protein targeting to mitochondrion; GO:0060491 regulation of cell projection assembly; GO:1903533 regulation of protein targeting; GO:0070486 leukocyte aggregation; GO:0060263 regulation of respiratory burst; GO:0010821 regulation of mitochondrion organization; GO:0009605 response to external stimulus; GO:0022610 biological adhesion; GO:0030036 actin cytoskeleton organization; GO:0032879 regulation of localization; GO:1903747 regulation of establishment of protein localization to mitochondrion; GO:0007155 cell adhesion; GO:0050921 positive regulation of chemotaxis; GO:0090022 regulation of neutrophil chemotaxis; GO:0051056 regulation of small GTPase mediated signal transduction; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0030168 platelet activation; GO:0080090 regulation of primary metabolic process; GO:0031346 positive regulation of cell projection organization; GO:0044763 single-organism cellular process; GO:0050670 regulation of lymphocyte proliferation; GO:0051272 positive regulation of cellular component movement; GO:0007264 small GTPase mediated signal transduction; GO:0031323 regulation of cellular metabolic process; GO:0006935 chemotaxis; GO:0032501 multicellular organismal process; GO:0050776 regulation of immune response; GO:1902745 positive regulation of lamellipodium organization; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0098602 single organism cell adhesion; GO:0071624 positive regulation of granulocyte chemotaxis; GO:0042330 taxis; GO:0002682 regulation of immune system process; GO:0051223 regulation of protein transport; GO:0050817 coagulation; GO:0002685 regulation of leukocyte migration; GO:0097435 supramolecular fiber organization; GO:0002687 positive regulation of leukocyte migration; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0042127 regulation of cell proliferation; GO:0031399 regulation of protein modification process; GO:0017157 regulation of exocytosis; GO:2000147 positive regulation of cell motility; GO:0002886 regulation of myeloid leukocyte mediated immunity; GO:0010310 regulation of hydrogen peroxide metabolic process; GO:0060249 anatomical structure homeostasis; GO:0060341 regulation of cellular localization; GO:2000145 regulation of cell motility; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:0051338 regulation of transferase activity; GO:0043300 regulation of leukocyte degranulation; GO:0032880 regulation of protein localization; GO:0007010 cytoskeleton organization; GO:0009966 regulation of signal transduction; GO:1902531 regulation of intracellular signal transduction; GO:0006950 response to stress; GO:0051270 regulation of cellular component movement; GO:0032101 regulation of response to external stimulus; GO:0030334 regulation of cell migration; GO:0030031 cell projection assembly; GO:0030155 regulation of cell adhesion; GO:0007186 G-protein coupled receptor signaling pathway; GO:1904951 positive regulation of establishment of protein localization; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0001775 cell activation; GO:0010810 regulation of cell-substrate adhesion; GO:0048584 positive regulation of response to stimulus; GO:0046849 bone remodeling; GO:1903827 regulation of cellular protein localization; GO:0008284 positive regulation of cell proliferation; GO:0050863 regulation of T cell activation; GO:0040017 positive regulation of locomotion; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0051046 regulation of secretion; GO:0033003 regulation of mast cell activation; GO:0051249 regulation of lymphocyte activation; GO:0048871 multicellular organismal homeostasis; GO:1903749 positive regulation of establishment of protein localization to mitochondrion; GO:0051130 positive regulation of cellular component organization; GO:0009611 response to wounding; GO:0016337 single organismal cell-cell adhesion; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0032103 positive regulation of response to external stimulus; GO:0070663 regulation of leukocyte proliferation; GO:1902624 positive regulation of neutrophil migration; GO:0002697 regulation of immune effector process; GO:0098609 cell-cell adhesion; GO:0010591 regulation of lamellipodium assembly; GO:0002688 regulation of leukocyte chemotaxis; GO:0048522 positive regulation of cellular process; GO:0032386 regulation of intracellular transport; GO:0043304 regulation of mast cell degranulation; GO:1903530 regulation of secretion by cell; GO:0023052 signaling; GO:0051050 positive regulation of transport; GO:1902589 single-organism organelle organization; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0050865 regulation of cell activation; GO:0030030 cell projection organization; GO:0010638 positive regulation of organelle organization; GO:0001894 tissue homeostasis; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0040011 locomotion; GO:0019220 regulation of phosphate metabolic process; GO:2000377 regulation of reactive oxygen species metabolic process; GO:0043549 regulation of kinase activity; GO:0051222 positive regulation of protein transport; GO:0071622 regulation of granulocyte chemotaxis; GO:0045859 regulation of protein kinase activity; GO:0071593 lymphocyte aggregation; GO:0016043 cellular component organization; GO:0007159 leukocyte cell-cell adhesion; GO:0090316 positive regulation of intracellular protein transport; GO:1903829 positive regulation of cellular protein localization; GO:0060255 regulation of macromolecule metabolic process; GO:0007015 actin filament organization; GO:0044087 regulation of cellular component biogenesis; GO:0031344 regulation of cell projection organization; GO:0050896 response to stimulus; GO:0070201 regulation of establishment of protein localization; GO:0007599 hemostasis; GO:0042592 homeostatic process; GO:0033006 regulation of mast cell activation involved in immune response; GO:0002690 positive regulation of leukocyte chemotaxis; GO:1902743 regulation of lamellipodium organization; GO:0010592 positive regulation of lamellipodium assembly; GO:0033157 regulation of intracellular protein transport; GO:0009987 cellular process; GO:0048771 tissue remodeling; GO:1902622 regulation of neutrophil migration; GO:0050878 regulation of body fluid levels; GO:0035556 intracellular signal transduction; GO:0032388 positive regulation of intracellular transport; GO:0051049 regulation of transport; GO:0002699 positive regulation of immune effector process; GO:0001932 regulation of protein phosphorylation; GO:0033043 regulation of organelle organization; GO:1903214 regulation of protein targeting to mitochondrion; GO:0042129 regulation of T cell proliferation; GO:0060753 regulation of mast cell chemotaxis; GO:0050920 regulation of chemotaxis; GO:1903305 regulation of regulated secretory pathway; GO:0048518 positive regulation of biological process; GO:0022407 regulation of cell-cell adhesion; GO:0010822 positive regulation of mitochondrion organization; GO:0045453 bone resorption; GO:0002703 regulation of leukocyte mediated immunity; GO:0090023 positive regulation of neutrophil chemotaxis; GO:0042060 wound healing; GO:0051246 regulation of protein metabolic process; GO:0002684 positive regulation of immune system process; GO:0051128 regulation of cellular component organization; GO:0040012 regulation of locomotion; GO:0044089 positive regulation of cellular component biogenesis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0044464 cell part; GO:0030670 phagocytic vesicle membrane; GO:0098805 whole membrane; GO:0030027 lamellipodium; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030055 cell-substrate junction; GO:0030139 endocytic vesicle; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0031252 cell leading edge; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0098588 bounding membrane of organelle; GO:0005635 nuclear envelope; GO:0030666 endocytic vesicle membrane; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0012505 endomembrane system; GO:0045335 phagocytic vesicle; GO:0012506 vesicle membrane; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0031975 envelope; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0019207 kinase regulator activity; GO:0098772 molecular function regulator; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0003924 GTPase activity; GO:0043168 anion binding; GO:0019001 guanyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0019887 protein kinase regulator activity; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0030234 enzyme regulator activity; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0032561 guanyl ribonucleotide binding; GO:0036094 small molecule binding; ","K07860","RAC2; Ras-related C3 botulinum toxin substrate 2","hsa05231 Choline metabolism in cancer - Homo sapiens (human); hsa04015 Rap1 signaling pathway - Homo sapiens (human); hsa04650 Natural killer cell mediated cytotoxicity - Homo sapiens (human); hsa04370 VEGF signaling pathway - Homo sapiens (human); hsa04662 B cell receptor signaling pathway - Homo sapiens (human); hsa04014 Ras signaling pathway - Homo sapiens (human); hsa04024 cAMP signaling pathway - Homo sapiens (human); hsa04670 Leukocyte transendothelial migration - Homo sapiens (human); hsa04010 MAPK signaling pathway - Homo sapiens (human); hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa04062 Chemokine signaling pathway - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa04666 Fc gamma R-mediated phagocytosis - Homo sapiens (human); hsa04664 Fc epsilon RI signaling pathway - Homo sapiens (human); hsa04071 Sphingolipid signaling pathway - Homo sapiens (human); hsa05416 Viral myocarditis - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa04520 Adherens junction - Homo sapiens (human); hsa04360 Axon guidance - Homo sapiens (human); hsa05210 Colorectal cancer - Homo sapiens (human); hsa05212 Pancreatic cancer - Homo sapiens (human); hsa04310 Wnt signaling pathway - Homo sapiens (human); ","IPR005225; IPR027417; ","Small GTP-binding protein domain; P-loop containing nucleoside triphosphate hydrolase; \r"]
["P15169","Carboxypeptidase N catalytic chain OS=Homo sapiens OX=9606 GN=CPN1","CPN1",52.286,46.536,22.7,8,9,8,1.068,1.023,0.972,0.963,0.978,1.011,0.964,0.303,"endoplasmic reticulum\r","GO:0065008 regulation of biological quality; GO:0006518 peptide metabolic process; GO:0016486 peptide hormone processing; GO:0016485 protein processing; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:1901142 insulin metabolic process; GO:0030070 insulin processing; GO:0071704 organic substance metabolic process; GO:0033993 response to lipid; GO:0008152 metabolic process; GO:0043171 peptide catabolic process; GO:0031960 response to corticosteroid; GO:0048545 response to steroid hormone; GO:0044248 cellular catabolic process; GO:0009719 response to endogenous stimulus; GO:0006508 proteolysis; GO:0034641 cellular nitrogen compound metabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0009987 cellular process; GO:0014070 response to organic cyclic compound; GO:0042445 hormone metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0010033 response to organic substance; GO:0043603 cellular amide metabolic process; GO:0044238 primary metabolic process; GO:0051384 response to glucocorticoid; GO:0010815 bradykinin catabolic process; GO:1901575 organic substance catabolic process; GO:1901565 organonitrogen compound catabolic process; GO:0042221 response to chemical; GO:0010817 regulation of hormone levels; GO:0010467 gene expression; GO:0009725 response to hormone; GO:0051604 protein maturation; GO:0009056 catabolic process; GO:0065007 biological regulation; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0043025 neuronal cell body; GO:0044424 intracellular part; GO:0005623 cell; GO:0098590 plasma membrane region; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0099503 secretory vesicle; GO:0097060 synaptic membrane; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0044456 synapse part; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0045202 synapse; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0044459 plasma membrane part; GO:0044297 cell body; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:0004180 carboxypeptidase activity; GO:0008233 peptidase activity; GO:0008238 exopeptidase activity; GO:0008235 metalloexopeptidase activity; GO:0043167 ion binding; GO:0016787 hydrolase activity; GO:0008237 metallopeptidase activity; GO:0008270 zinc ion binding; GO:0046914 transition metal ion binding; GO:0004181 metallocarboxypeptidase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0046872 metal ion binding; GO:0043169 cation binding; ","K01292",null,null,"IPR008969; IPR000834; IPR014766; ","\"Carboxypeptidase-like, regulatory domain; Peptidase M14, carboxypeptidase A; Carboxypeptidase, regulatory domain; \"\r"]
["P15170","Eukaryotic peptide chain release factor GTP-binding subunit ERF3A OS=Homo sapiens OX=9606 GN=GSPT1","GSPT1",55.755,55.613,22.8,10,14,10,0.934,0.932,0.9,1.007,1.092,1.074,1.147,7.6E-3,"cyto_nucl\r","GO:0006518 peptide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0032259 methylation; GO:0043241 protein complex disassembly; GO:0008213 protein alkylation; GO:0008152 metabolic process; GO:0002181 cytoplasmic translation; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:1901361 organic cyclic compound catabolic process; GO:0044770 cell cycle phase transition; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0006412 translation; GO:0000278 mitotic cell cycle; GO:0010468 regulation of gene expression; GO:0071822 protein complex subunit organization; GO:0043043 peptide biosynthetic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0016070 RNA metabolic process; GO:0006401 RNA catabolic process; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0050789 regulation of biological process; GO:0006415 translational termination; GO:0090304 nucleic acid metabolic process; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006464 cellular protein modification process; GO:0036211 protein modification process; GO:0016071 mRNA metabolic process; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0044267 cellular protein metabolic process; GO:0048519 negative regulation of biological process; GO:1901566 organonitrogen compound biosynthetic process; GO:1903047 mitotic cell cycle process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0006479 protein methylation; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0043624 cellular protein complex disassembly; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0000082 G1/S transition of mitotic cell cycle; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0044772 mitotic cell cycle phase transition; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0044843 cell cycle G1/S phase transition; GO:0010629 negative regulation of gene expression; GO:0006807 nitrogen compound metabolic process; GO:0032984 macromolecular complex disassembly; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0043414 macromolecule methylation; GO:0009057 macromolecule catabolic process; GO:0022411 cellular component disassembly; GO:0010467 gene expression; GO:0022402 cell cycle process; GO:0043604 amide biosynthetic process; GO:0043412 macromolecule modification; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0002184 cytoplasmic translational termination; GO:0065007 biological regulation; GO:0046700 heterocycle catabolic process; GO:0071840 cellular component organization or biogenesis; GO:1901564 organonitrogen compound metabolic process; ","GO:0018444 translation release factor complex; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0043234 protein complex; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0003924 GTPase activity; GO:0043168 anion binding; GO:0019001 guanyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005525 GTP binding; GO:0003747 translation release factor activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0008079 translation termination factor activity; GO:0003723 RNA binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0008135 translation factor activity, RNA binding; GO:0097367 carbohydrate derivative binding; GO:0003676 nucleic acid binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0032561 guanyl ribonucleotide binding; GO:0036094 small molecule binding; ","K03267","ERF3; peptide chain release factor subunit 3","hsa03015 mRNA surveillance pathway - Homo sapiens (human); ","IPR004160; IPR004161; IPR027417; IPR009001; IPR000795; IPR009000; ","\"Translation elongation factor EFTu/EF1A, C-terminal; Translation elongation factor EFTu-like, domain 2; P-loop containing nucleoside triphosphate hydrolase; Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal; Transcription factor, GTP-binding domain; Translation protein, beta-barrel domain; \"\r"]
["P15289","Arylsulfatase A OS=Homo sapiens OX=9606 GN=ARSA","ARSA",53.588,20.404,12.8,5,6,5,1.145,0.98,1.025,0.922,0.862,1.079,0.909,0.294,"extracellular\r","GO:0043687 post-translational protein modification; GO:1903509 liposaccharide metabolic process; GO:0045321 leukocyte activation; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0006643 membrane lipid metabolic process; GO:0006687 glycosphingolipid metabolic process; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:1901135 carbohydrate derivative metabolic process; GO:0006665 sphingolipid metabolic process; GO:0036230 granulocyte activation; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0009987 cellular process; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0006629 lipid metabolic process; GO:0002443 leukocyte mediated immunity; GO:0002446 neutrophil mediated immunity; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0006664 glycolipid metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0002376 immune system process; GO:0043312 neutrophil degranulation; GO:0044238 primary metabolic process; GO:0002263 cell activation involved in immune response; GO:0002444 myeloid leukocyte mediated immunity; GO:0006810 transport; GO:0002366 leukocyte activation involved in immune response; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:0032940 secretion by cell; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0001775 cell activation; GO:0006464 cellular protein modification process; GO:0043299 leukocyte degranulation; GO:0051179 localization; GO:0006955 immune response; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:0006887 exocytosis; GO:1901564 organonitrogen compound metabolic process; ","GO:0034774 secretory granule lumen; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0005788 endoplasmic reticulum lumen; GO:0097708 intracellular vesicle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0043202 lysosomal lumen; GO:0042582 azurophil granule; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0044432 endoplasmic reticulum part; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0004065 arylsulfatase activity; GO:0008484 sulfuric ester hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0004098 cerebroside-sulfatase activity; GO:0005509 calcium ion binding; ","K01134","ARSA; arylsulfatase A [EC:3.1.6.8]","hsa04142 Lysosome - Homo sapiens (human); hsa00600 Sphingolipid metabolism - Homo sapiens (human); ","IPR017849; IPR017850; IPR000917; ","\"Alkaline phosphatase-like, alpha/beta/alpha; Alkaline-phosphatase-like, core domain; Sulfatase, N-terminal; \"\r"]
["P15309","Prostatic acid phosphatase OS=Homo sapiens OX=9606 GN=ACPP","ACPP",44.566,53.559,24.9,9,14,9,0.674,0.809,0.816,1.241,1.168,1.183,1.562,2.3E-3,"extracellular\r","GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0045321 leukocyte activation; GO:0023051 regulation of signaling; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0006772 thiamine metabolic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0010646 regulation of cell communication; GO:0006753 nucleoside phosphate metabolic process; GO:0031644 regulation of neurological system process; GO:0044057 regulation of system process; GO:0072527 pyrimidine-containing compound metabolic process; GO:0042723 thiamine-containing compound metabolic process; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0006790 sulfur compound metabolic process; GO:0002443 leukocyte mediated immunity; GO:0002446 neutrophil mediated immunity; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0008277 regulation of G-protein coupled receptor protein signaling pathway; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0032940 secretion by cell; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway; GO:0009112 nucleobase metabolic process; GO:0043299 leukocyte degranulation; GO:1901657 glycosyl compound metabolic process; GO:0050794 regulation of cellular process; GO:0002283 neutrophil activation involved in immune response; GO:0006725 cellular aromatic compound metabolic process; GO:0002252 immune effector process; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:0071704 organic substance metabolic process; GO:0006766 vitamin metabolic process; GO:0046483 heterocycle metabolic process; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0006139 nucleobase-containing compound metabolic process; GO:0023056 positive regulation of signaling; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0051930 regulation of sensory perception of pain; GO:0010647 positive regulation of cell communication; GO:0036230 granulocyte activation; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0060167 regulation of adenosine receptor signaling pathway; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:0009119 ribonucleoside metabolic process; GO:0006767 water-soluble vitamin metabolic process; GO:0051931 regulation of sensory perception; GO:0016192 vesicle-mediated transport; GO:0046085 adenosine metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0002376 immune system process; GO:0006144 purine nucleobase metabolic process; GO:0044238 primary metabolic process; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0016311 dephosphorylation; GO:0002263 cell activation involved in immune response; GO:0060168 positive regulation of adenosine receptor signaling pathway; GO:0002366 leukocyte activation involved in immune response; GO:0046128 purine ribonucleoside metabolic process; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0006793 phosphorus metabolic process; GO:0019637 organophosphate metabolic process; GO:0001775 cell activation; GO:0009967 positive regulation of signal transduction; GO:0048584 positive regulation of response to stimulus; GO:0006955 immune response; GO:0051179 localization; GO:0065007 biological regulation; GO:1901564 organonitrogen compound metabolic process; GO:0006887 exocytosis; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0098858 actin-based cell projection; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0005765 lysosomal membrane; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0098805 whole membrane; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030175 filopodium; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0042995 cell projection; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0035577 azurophil granule membrane; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0042582 azurophil granule; GO:0098852 lytic vacuole membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0030667 secretory granule membrane; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0052642 lysophosphatidic acid phosphatase activity; GO:0008253 5'-nucleotidase activity; GO:0042802 identical protein binding; GO:0003993 acid phosphatase activity; GO:0003824 catalytic activity; GO:0042578 phosphoric ester hydrolase activity; GO:0008252 nucleotidase activity; GO:0005488 binding; GO:0016791 phosphatase activity; GO:0016788 hydrolase activity, acting on ester bonds; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0042131 thiamine phosphate phosphatase activity; ","K19283"]
["P15311","Ezrin OS=Homo sapiens OX=9606 GN=EZR","EZR",69.412,97.203,47.8,38,75,25,0.85,0.828,0.842,1.167,1.17,1.122,1.373,3.73e-05,"cytoplasm\r",{"$cut":{"chars":16907,"head":"GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0032872 regulation of stress-activated MAPK cascade; GO:0046847 filopodium assembly; GO:0046683 response to organophosphorus; GO:0044237 cellular metabolic process; GO:0045927 positive regulation of growth; GO:1903364 positive regulation of cellular protein catabolic process; GO:0008152 metabolic process; GO:1902896 terminal web assembly; GO:0008360 regulation of cell shape; GO:0032535 regulation of cellular component size; GO:0051051 negative regulation of transport; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0002064 epithelial cell development; GO:0050709 negative regulation of protein secretion; GO:0040014 regulation of multicellular organism growth; GO:0001951 intestinal D-glucose absorption; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0061842 microtubule organizing center localization; GO:1903531 negative regulation of secretion by cell; GO:0044763 single-organism cellular process; GO:1905668 positive regulation of protein localization to endosome; GO:0006935 chemotaxis; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0031532 actin cytoskeleton reorganization; GO:0000226 microtubule cytoskeleton organization; GO:0010243 response to organonitrogen compound; GO:0080135 regulation of cellular response to stress; GO:0051591 response to cAMP; GO:1902532 negative regulation of intracellular signal transduction; GO:0008645 hexose transport; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0098602 single organism cell adhesion; GO:0044260 cellular macromolecule metabolic process; GO:0051223 regulation of protein transport; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0030855 epithelial cell differentiation; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0051640 organelle localization; GO:0032532 regulation of microvillus length; GO:0044707 single-multicellular organism process; GO:0015749 monosaccharide transport; GO:1900041 negative regulation of interleukin-2 secretion; GO:1903076 regulation of protein localization to plasma membrane; GO:1901700 response to oxygen-containing compound; GO:0007051 spindle organization; GO:0048519 negative regulation of biological process; GO:0045892 negative regulation of transcription, DNA-templated; GO:0009653 anatomical structure morphogenesis; GO:0010737 protein kinase A signaling; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0009889 regulation of biosynthetic process; GO:0009896 positive regulation of catabolic process; GO:2000641 regulation of early endosome to late endosome transport; GO:1902580 single-organism cellular localization; GO:0042176 regulation of protein catabolic process; GO:0061245 establishment or maintenance of bipolar cell polarity; GO:0034613 cellular protein localization; GO:0048015 phosphatidylinositol-mediated signaling; GO:0090150 establishment of protein localization to membrane; GO:0010033 response to organic substance; GO:0031122 cytoplasmic microtubule organization; GO:0007186 G-protein coupled receptor signaling pathway; GO:0009890 negative regulation of biosynthetic process; GO:0072659 protein localization to plasma membrane; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:1903753 negative regulation of p38MAPK cascade; GO:0045936 negative regulation of phosphate metabolic process; GO:1903827 regulation of cellular protein localization; GO:0090520 sphingolipid mediated signaling pathway; GO:0010256 endomembrane system organization; GO:0031623 receptor internalization; GO:0009968 negative regulation of signal transduction; GO:0050892 intestinal absorption; GO:0048666 neuron development; GO:0023051 regulation of signaling; GO:0048869 cellular developmental process; GO:0031331 positive regulation of cellular catabolic process; GO:0051046 regulation of secretion; GO:004"}},"GO:0016020 membrane; GO:0098862 cluster of actin-based cell projections; GO:0044421 extracellular region part; GO:0019898 extrinsic component of membrane; GO:0098857 membrane microdomain; GO:0032587 ruffle membrane; GO:0099568 cytoplasmic region; GO:0005737 cytoplasm; GO:0099080 supramolecular complex; GO:0098858 actin-based cell projection; GO:0005623 cell; GO:0009898 cytoplasmic side of plasma membrane; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0030315 T-tubule; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0098590 plasma membrane region; GO:0031256 leading edge membrane; GO:0043209 myelin sheath; GO:0005622 intracellular; GO:0098589 membrane region; GO:0030175 filopodium; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0045177 apical part of cell; GO:0043233 organelle lumen; GO:0005924 cell-substrate adherens junction; GO:0098592 cytoplasmic side of apical plasma membrane; GO:0098552 side of membrane; GO:0005929 cilium; GO:0031252 cell leading edge; GO:0099513 polymeric cytoskeletal fiber; GO:0042995 cell projection; GO:0044430 cytoskeletal part; GO:0070161 anchoring junction; GO:0031981 nuclear lumen; GO:0036064 ciliary basal body; GO:0044452 nucleolar part; GO:0005730 nucleolus; GO:0001650 fibrillar center; GO:0005576 extracellular region; GO:0099081 supramolecular polymer; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0005902 microvillus; GO:0001772 immunological synapse; GO:0042383 sarcolemma; GO:0043230 extracellular organelle; GO:0016323 basolateral plasma membrane; GO:0005615 extracellular space; GO:0005938 cell cortex; GO:0005903 brush border; GO:0016324 apical plasma membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0031982 vesicle; GO:0030863 cortical cytoskeleton; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0098562 cytoplasmic side of membrane; GO:0097386 glial cell projection; GO:0005856 cytoskeleton; GO:0031974 membrane-enclosed lumen; GO:0005815 microtubule organizing center; GO:0097454 Schwann cell microvillus; GO:0070013 intracellular organelle lumen; GO:0044441 ciliary part; GO:0015630 microtubule cytoskeleton; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0005912 adherens junction; GO:0048471 perinuclear region of cytoplasm; GO:0005884 actin filament; GO:0005768 endosome; GO:0045121 membrane raft; GO:0044393 microspike; GO:0031528 microvillus membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0001931 uropod; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0031254 cell trailing edge; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0015629 actin cytoskeleton; GO:0097449 astrocyte projection; GO:0043226 organelle; GO:0051286 cell tip; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0044853 plasma membrane raft; GO:0044448 cell cortex part; GO:0031253 cell projection membrane; GO:0001726 ruffle; GO:0044297 cell body; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0051015 actin filament binding; GO:0003723 RNA binding; GO:0051018 protein kinase A binding; GO:0051117 ATPase binding; GO:0034237 protein kinase A regulatory subunit binding; GO:0019901 protein kinase binding; GO:0044877 macromolecular complex binding; GO:0015631 tubulin binding; GO:0005515 protein binding; GO:0019900 kinase binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0050839 cell adhesion molecule binding; GO:0008092 cytoskeletal protein binding; GO:0005488 binding; GO:0008017 microtubule binding; GO:0003676 nucleic acid binding; GO:0045296 cadherin binding; GO:0003779 actin binding; GO:0019904 protein domain specific binding; GO:0044548 S100 protein binding; GO:0034236 protein kinase A catalytic subunit binding; GO:0019899 enzyme binding; GO:0032403 protein complex binding; ","K08007","VIL2; villin 2 (ezrin)","hsa04670 Leukocyte transendothelial migration - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa05206 MicroRNAs in cancer - Homo sapiens (human); hsa04530 Tight junction - Homo sapiens (human); hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human); hsa04971 Gastric acid secretion - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); ","IPR019748; IPR018980; IPR008954; IPR019749; IPR018979; IPR029071; IPR011993; IPR011259; IPR014352; IPR000299; ","\"FERM central domain; FERM, C-terminal PH-like domain; Moesin tail domain; Band 4.1 domain; FERM, N-terminal; Ubiquitin-related domain; PH domain-like; Ezrin/radixin/moesin, C-terminal; FERM/acyl-CoA-binding protein, 3-helical bundle; FERM domain; \"\r"]
["P15313","V-type proton ATPase subunit B, kidney isoform OS=Homo sapiens OX=9606 GN=ATP6V1B1","ATP6V1B1",56.832,2.2728,17,7,7,1,1.191,1.114,1.175,0.839,0.863,0.844,0.732,0.000143,"cytoplasm\r","GO:0044700 single organism signaling; GO:0009116 nucleoside metabolic process; GO:0065008 regulation of biological quality; GO:0007166 cell surface receptor signaling pathway; GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient; GO:0030641 regulation of cellular pH; GO:0030004 cellular monovalent inorganic cation homeostasis; GO:0044237 cellular metabolic process; GO:0050877 neurological system process; GO:0015031 protein transport; GO:0000041 transition metal ion transport; GO:0008152 metabolic process; GO:0048562 embryonic organ morphogenesis; GO:0055065 metal ion homeostasis; GO:0019693 ribose phosphate metabolic process; GO:0009719 response to endogenous stimulus; GO:0008104 protein localization; GO:0009790 embryo development; GO:1901652 response to peptide; GO:0048598 embryonic morphogenesis; GO:0090596 sensory organ morphogenesis; GO:0044765 single-organism transport; GO:0051716 cellular response to stimulus; GO:0090383 phagosome acidification; GO:0031329 regulation of cellular catabolic process; GO:0001503 ossification; GO:0009894 regulation of catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0031323 regulation of cellular metabolic process; GO:0033572 transferrin transport; GO:0010506 regulation of autophagy; GO:0032501 multicellular organismal process; GO:0016241 regulation of macroautophagy; GO:0006810 transport; GO:0048513 animal organ development; GO:0010243 response to organonitrogen compound; GO:0043583 ear development; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:1901698 response to nitrogen compound; GO:0032869 cellular response to insulin stimulus; GO:0009887 animal organ morphogenesis; GO:0009126 purine nucleoside monophosphate metabolic process; GO:0098662 inorganic cation transmembrane transport; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0034220 ion transmembrane transport; GO:0006885 regulation of pH; GO:0030001 metal ion transport; GO:0009259 ribonucleotide metabolic process; GO:1901700 response to oxygen-containing compound; GO:0009653 anatomical structure morphogenesis; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0007275 multicellular organism development; GO:0099131 ATP hydrolysis coupled ion transmembrane transport; GO:0009119 ribonucleoside metabolic process; GO:0048878 chemical homeostasis; GO:0048731 system development; GO:0071702 organic substance transport; GO:0009141 nucleoside triphosphate metabolic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0048839 inner ear development; GO:0006163 purine nucleotide metabolic process; GO:0045184 establishment of protein localization; GO:0072512 trivalent inorganic cation transport; GO:0055085 transmembrane transport; GO:0007588 excretion; GO:0006873 cellular ion homeostasis; GO:0051453 regulation of intracellular pH; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0006811 ion transport; GO:0019637 organophosphate metabolic process; GO:0007605 sensory perception of sound; GO:0007423 sensory organ development; GO:0051179 localization; GO:0015672 monovalent inorganic cation transport; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0008286 insulin receptor signaling pathway; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0090662 ATP hydrolysis coupled transmembrane transport; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0042472 inner ear morphogenesis; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:0007154 cell communication; GO:1901653 cellular response to peptide; GO:0006753 nucleoside phosphate metabolic process; GO:0033036 macromolecule localization; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0007600 sensory perception; GO:0098655 cation transmembrane transport; GO:0050801 ion homeostasis; GO:0015682 ferric iron transport; GO:0055074 calcium ion homeostasis; GO:0098771 inorganic ion homeostasis; GO:1901360 organic cyclic compound metabolic process; GO:0019725 cellular homeostasis; GO:0023052 signaling; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0071417 cellular response to organonitrogen compound; GO:0042221 response to chemical; GO:0032868 response to insulin; GO:0050789 regulation of biological process; GO:0043434 response to peptide hormone; GO:1901699 cellular response to nitrogen compound; GO:0032870 cellular response to hormone stimulus; GO:0015991 ATP hydrolysis coupled proton transport; GO:0019222 regulation of metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0048856 anatomical structure development; GO:0072507 divalent inorganic cation homeostasis; GO:0050954 sensory perception of mechanical stimulus; GO:0016043 cellular component organization; GO:0045851 pH reduction; GO:0006725 cellular aromatic compound metabolic process; GO:0048568 embryonic organ development; GO:0071310 cellular response to organic substance; GO:0030003 cellular cation homeostasis; GO:0006826 iron ion transport; GO:0050896 response to stimulus; GO:0055082 cellular chemical homeostasis; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0006812 cation transport; GO:0055080 cation homeostasis; GO:0071375 cellular response to peptide hormone stimulus; GO:1902600 hydrogen ion transmembrane transport; GO:0034641 cellular nitrogen compound metabolic process; GO:0099132 ATP hydrolysis coupled cation transmembrane transport; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0046034 ATP metabolic process; GO:0055067 monovalent inorganic cation homeostasis; GO:0090382 phagosome maturation; GO:0003008 system process; GO:0098660 inorganic ion transmembrane transport; GO:0006807 nitrogen compound metabolic process; GO:0006818 hydrogen transport; GO:0015992 proton transport; GO:0046128 purine ribonucleoside metabolic process; GO:1901701 cellular response to oxygen-containing compound; GO:0044767 single-organism developmental process; GO:0071495 cellular response to endogenous stimulus; GO:0042471 ear morphogenesis; GO:0009150 purine ribonucleotide metabolic process; GO:0051452 intracellular pH reduction; GO:0009725 response to hormone; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0019898 extrinsic component of membrane; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0033176 proton-transporting V-type ATPase complex; GO:0098858 actin-based cell projection; GO:0005623 cell; GO:0044422 organelle part; GO:0070382 exocytic vesicle; GO:0070062 extracellular exosome; GO:0098590 plasma membrane region; GO:0008021 synaptic vesicle; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0045177 apical part of cell; GO:0042995 cell projection; GO:0012506 vesicle membrane; GO:0030672 synaptic vesicle membrane; GO:0005576 extracellular region; GO:0016328 lateral plasma membrane; GO:0033180 proton-transporting V-type ATPase, V1 domain; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0044437 vacuolar part; GO:0016469 proton-transporting two-sector ATPase complex; GO:0005902 microvillus; GO:0005773 vacuole; GO:0043234 protein complex; GO:0030133 transport vesicle; GO:0043230 extracellular organelle; GO:0016323 basolateral plasma membrane; GO:0030658 transport vesicle membrane; GO:0016324 apical plasma membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0099501 exocytic vesicle membrane; GO:0044425 membrane part; GO:0044464 cell part; GO:0098793 presynapse; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0044456 synapse part; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0045202 synapse; GO:0016471 vacuolar proton-transporting V-type ATPase complex; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0031312 extrinsic component of organelle membrane; GO:0005774 vacuolar membrane; GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain; GO:0098850 extrinsic component of synaptic vesicle membrane; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0015077 monovalent inorganic cation transmembrane transporter activity; GO:0015078 hydrogen ion transmembrane transporter activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0022890 inorganic cation transmembrane transporter activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005215 transporter activity; GO:0022804 active transmembrane transporter activity; GO:0005524 ATP binding; GO:0015075 ion transmembrane transporter activity; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0008324 cation transmembrane transporter activity; GO:0032403 protein complex binding; GO:0036094 small molecule binding; GO:0022857 transmembrane transporter activity; ","K02147","ATPeV1B; V-type H+-transporting ATPase subunit B","hsa05120 Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human); hsa04966 Collecting duct acid secretion - Homo sapiens (human); hsa05323 Rheumatoid arthritis - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa04150 mTOR signaling pathway - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05110 Vibrio cholerae infection - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); hsa04721 Synaptic vesicle cycle - Homo sapiens (human); ","IPR004100; IPR000194; IPR027417; ","\"ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain; ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain; P-loop containing nucleoside triphosphate hydrolase; \"\r"]
["P15374","Ubiquitin carboxyl-terminal hydrolase isozyme L3 OS=Homo sapiens OX=9606 GN=UCHL3","UCHL3",26.182,50.716,33,5,8,5,0.957,0.954,0.962,1.024,1.072,1.044,1.093,0.00278,"cytoplasm\r","GO:0043632 modification-dependent macromolecule catabolic process; GO:0070646 protein modification by small protein removal; GO:0044265 cellular macromolecule catabolic process; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0016567 protein ubiquitination; GO:0019941 modification-dependent protein catabolic process; GO:0044267 cellular protein metabolic process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0016579 protein deubiquitination; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:1901575 organic substance catabolic process; GO:0008152 metabolic process; GO:0032446 protein modification by small protein conjugation; GO:0030163 protein catabolic process; GO:0009057 macromolecule catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0044248 cellular catabolic process; GO:0006508 proteolysis; GO:0006464 cellular protein modification process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:0009056 catabolic process; GO:0009987 cellular process; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0004843 thiol-dependent ubiquitin-specific protease activity; GO:0019784 NEDD8-specific protease activity; GO:0008233 peptidase activity; GO:0036459 thiol-dependent ubiquitinyl hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043130 ubiquitin binding; GO:0101005 ubiquitinyl hydrolase activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0019783 ubiquitin-like protein-specific protease activity; GO:0005515 protein binding; GO:0008234 cysteine-type peptidase activity; GO:0016787 hydrolase activity; GO:0032182 ubiquitin-like protein binding; ","K05609",null,null,"IPR001578; ","\"Peptidase C12, ubiquitin carboxyl-terminal hydrolase; \"\r"]
["P15529","Membrane cofactor protein OS=Homo sapiens OX=9606 GN=CD46","CD46",43.747,8.4322,3.8,1,1,1,1.125,1.052,1.105,0.963,0.903,0.873,0.835,0.00666,"plasma membrane\r","GO:0044409 entry into host; GO:0002694 regulation of leukocyte activation; GO:0016064 immunoglobulin mediated immune response; GO:0032944 regulation of mononuclear cell proliferation; GO:0022414 reproductive process; GO:0002698 negative regulation of immune effector process; GO:1903318 negative regulation of protein maturation; GO:0045916 negative regulation of complement activation; GO:0031347 regulation of defense response; GO:0006956 complement activation; GO:0008152 metabolic process; GO:0032946 positive regulation of mononuclear cell proliferation; GO:0051240 positive regulation of multicellular organismal process; GO:0044702 single organism reproductive process; GO:0006958 complement activation, classical pathway; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0044419 interspecies interaction between organisms; GO:0045621 positive regulation of lymphocyte differentiation; GO:0046718 viral entry into host cell; GO:0032733 positive regulation of interleukin-10 production; GO:0002443 leukocyte mediated immunity; GO:0080090 regulation of primary metabolic process; GO:0002456 T cell mediated immunity; GO:0019953 sexual reproduction; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0050670 regulation of lymphocyte proliferation; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0048583 regulation of response to stimulus; GO:0010604 positive regulation of macromolecule metabolic process; GO:0002682 regulation of immune system process; GO:1903317 regulation of protein maturation; GO:0051094 positive regulation of developmental process; GO:0045589 regulation of regulatory T cell differentiation; GO:0000003 reproduction; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0030449 regulation of complement activation; GO:2000257 regulation of protein activation cascade; GO:1900115 extracellular regulation of signal transduction; GO:0042127 regulation of cell proliferation; GO:0045580 regulation of T cell differentiation; GO:0001819 positive regulation of cytokine production; GO:0051806 entry into cell of other organism involved in symbiotic interaction; GO:0002920 regulation of humoral immune response; GO:0010955 negative regulation of protein processing; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0051239 regulation of multicellular organismal process; GO:0045597 positive regulation of cell differentiation; GO:0019724 B cell mediated immunity; GO:1903706 regulation of hemopoiesis; GO:2000258 negative regulation of protein activation cascade; GO:0050867 positive regulation of cell activation; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0010628 positive regulation of gene expression; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:0002449 lymphocyte mediated immunity; GO:0009966 regulation of signal transduction; GO:0050778 positive regulation of immune response; GO:0002253 activation of immune response; GO:0045861 negative regulation of proteolysis; GO:0071634 regulation of transforming growth factor beta production; GO:0006950 response to stress; GO:0045785 positive regulation of cell adhesion; GO:0043382 positive regulation of memory T cell differentiation; GO:0072376 protein activation cascade; GO:0002376 immune system process; GO:0032101 regulation of response to external stimulus; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0045582 positive regulation of T cell differentiation; GO:0009892 negative regulation of metabolic process; GO:1903039 positive regulation of leukocyte cell-cell adhesion; GO:0030155 regulation of cell adhesion; GO:0002696 positive regulation of leukocyte activation; GO:0001816 cytokine production; GO:0050870 positive regulation of T cell activation; GO:0070613 regulation of protein processing; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0048584 positive regulation of response to stimulus; GO:0006955 immune response; GO:0050793 regulation of developmental process; GO:0008284 positive regulation of cell proliferation; GO:0050863 regulation of T cell activation; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0051249 regulation of lymphocyte activation; GO:0045591 positive regulation of regulatory T cell differentiation; GO:1902107 positive regulation of leukocyte differentiation; GO:0050671 positive regulation of lymphocyte proliferation; GO:0010646 regulation of cell communication; GO:0009893 positive regulation of metabolic process; GO:0002250 adaptive immune response; GO:0070663 regulation of leukocyte proliferation; GO:0050777 negative regulation of immune response; GO:0002697 regulation of immune effector process; GO:0010468 regulation of gene expression; GO:0048522 positive regulation of cellular process; GO:0051251 positive regulation of lymphocyte activation; GO:0010605 negative regulation of macromolecule metabolic process; GO:0032613 interleukin-10 production; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0008593 regulation of Notch signaling pathway; GO:0002683 negative regulation of immune system process; GO:0009566 fertilization; GO:0030260 entry into host cell; GO:0050789 regulation of biological process; GO:0050865 regulation of cell activation; GO:0032268 regulation of cellular protein metabolic process; GO:1900116 extracellular negative regulation of signal transduction; GO:0051828 entry into other organism involved in symbiotic interaction; GO:1902105 regulation of leukocyte differentiation; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0006952 defense response; GO:2000026 regulation of multicellular organismal development; GO:0043380 regulation of memory T cell differentiation; GO:0042102 positive regulation of T cell proliferation; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0002673 regulation of acute inflammatory response; GO:0006959 humoral immune response; GO:0031324 negative regulation of cellular metabolic process; GO:0002921 negative regulation of humoral immune response; GO:0050896 response to stimulus; GO:0045087 innate immune response; GO:0071704 organic substance metabolic process; GO:0016032 viral process; GO:0035581 sequestering of extracellular ligand from receptor; GO:0006508 proteolysis; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:1903708 positive regulation of hemopoiesis; GO:0010629 negative regulation of gene expression; GO:0022409 positive regulation of cell-cell adhesion; GO:0002699 positive regulation of immune effector process; GO:0042129 regulation of T cell proliferation; GO:0048585 negative regulation of response to stimulus; GO:0007338 single fertilization; GO:0051701 interaction with host; GO:0048518 positive regulation of biological process; GO:0022407 regulation of cell-cell adhesion; GO:0045619 regulation of lymphocyte differentiation; GO:0032653 regulation of interleukin-10 production; GO:0070665 positive regulation of leukocyte proliferation; GO:0051246 regulation of protein metabolic process; GO:0044703 multi-organism reproductive process; GO:0002684 positive regulation of immune system process; GO:0050727 regulation of inflammatory response; GO:0001817 regulation of cytokine production; GO:0051248 negative regulation of protein metabolic process; GO:0071636 positive regulation of transforming growth factor beta production; GO:0065007 biological regulation; ","GO:0016323 basolateral plasma membrane; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0002079 inner acrosomal membrane; GO:0098590 plasma membrane region; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0098805 whole membrane; GO:0099503 secretory vesicle; GO:0005912 adherens junction; GO:0098589 membrane region; GO:1903561 extracellular vesicle; GO:0030055 cell-substrate junction; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0031226 intrinsic component of plasma membrane; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0002080 acrosomal membrane; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0030667 secretory granule membrane; GO:0044459 plasma membrane part; GO:0001669 acrosomal vesicle; GO:0009986 cell surface; GO:0005794 Golgi apparatus; GO:0097223 sperm part; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0008233 peptidase activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0004857 enzyme inhibitor activity; GO:0001618 virus receptor activity; GO:0004175 endopeptidase activity; GO:0050839 cell adhesion molecule binding; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0030234 enzyme regulator activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0045296 cadherin binding; GO:0001848 complement binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; ","K04007","CD46; membrane cofactor protein","hsa05162 Measles - Homo sapiens (human); hsa04610 Complement and coagulation cascades - Homo sapiens (human); ","IPR000436; ","Sushi/SCR/CCP domain; \r"]
["P15531","Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1","NME1",17.149,14.996,57.9,10,21,4,0.857,1.004,0.988,1.028,1.164,1.023,1.128,0.138,"cytoplasm\r","GO:0010941 regulation of cell death; GO:0009116 nucleoside metabolic process; GO:0006165 nucleoside diphosphate phosphorylation; GO:0009147 pyrimidine nucleoside triphosphate metabolic process; GO:0046129 purine ribonucleoside biosynthetic process; GO:0009163 nucleoside biosynthetic process; GO:0044237 cellular metabolic process; GO:0008285 negative regulation of cell proliferation; GO:0046390 ribose phosphate biosynthetic process; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0006213 pyrimidine nucleoside metabolic process; GO:1901068 guanosine-containing compound metabolic process; GO:0050678 regulation of epithelial cell proliferation; GO:0044093 positive regulation of molecular function; GO:0072527 pyrimidine-containing compound metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0043170 macromolecule metabolic process; GO:0051099 positive regulation of binding; GO:0009145 purine nucleoside triphosphate biosynthetic process; GO:0007399 nervous system development; GO:0018130 heterocycle biosynthetic process; GO:0009206 purine ribonucleoside triphosphate biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0046051 UTP metabolic process; GO:0032501 multicellular organismal process; GO:0046131 pyrimidine ribonucleoside metabolic process; GO:0043388 positive regulation of DNA binding; GO:0006810 transport; GO:0090407 organophosphate biosynthetic process; GO:0044710 single-organism metabolic process; GO:0006228 UTP biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0006164 purine nucleotide biosynthetic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0009201 ribonucleoside triphosphate biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0016310 phosphorylation; GO:0042127 regulation of cell proliferation; GO:0006259 DNA metabolic process; GO:0009259 ribonucleotide metabolic process; GO:0043067 regulation of programmed cell death; GO:0006221 pyrimidine nucleotide biosynthetic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0009220 pyrimidine ribonucleotide biosynthetic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0007275 multicellular organism development; GO:0009119 ribonucleoside metabolic process; GO:0009218 pyrimidine ribonucleotide metabolic process; GO:0044711 single-organism biosynthetic process; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0009148 pyrimidine nucleoside triphosphate biosynthetic process; GO:0042455 ribonucleoside biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0006163 purine nucleotide metabolic process; GO:0006220 pyrimidine nucleotide metabolic process; GO:0006793 phosphorus metabolic process; GO:0009260 ribonucleotide biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0009209 pyrimidine ribonucleoside triphosphate biosynthetic process; GO:0051179 localization; GO:0008284 positive regulation of cell proliferation; GO:1901564 organonitrogen compound metabolic process; GO:0046132 pyrimidine ribonucleoside biosynthetic process; GO:0042278 purine nucleoside metabolic process; GO:0009117 nucleotide metabolic process; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0046939 nucleotide phosphorylation; GO:0046036 CTP metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0046134 pyrimidine nucleoside biosynthetic process; GO:0006753 nucleoside phosphate metabolic process; GO:1901070 guanosine-containing compound biosynthetic process; GO:0006183 GTP biosynthetic process; GO:0032502 developmental process; GO:0051098 regulation of binding; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0042451 purine nucleoside biosynthetic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0072522 purine-containing compound biosynthetic process; GO:0065009 regulation of molecular function; GO:1901657 glycosyl compound metabolic process; GO:0048856 anatomical structure development; GO:0046039 GTP metabolic process; GO:0009165 nucleotide biosynthetic process; GO:0009208 pyrimidine ribonucleoside triphosphate metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0015949 nucleobase-containing small molecule interconversion; GO:0009142 nucleoside triphosphate biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0051101 regulation of DNA binding; GO:0071704 organic substance metabolic process; GO:0072528 pyrimidine-containing compound biosynthetic process; GO:0030154 cell differentiation; GO:0006241 CTP biosynthetic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0009987 cellular process; GO:0009132 nucleoside diphosphate metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0046128 purine ribonucleoside metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0009152 purine ribonucleotide biosynthetic process; GO:0044767 single-organism developmental process; GO:1901659 glycosyl compound biosynthetic process; GO:0009150 purine ribonucleotide metabolic process; GO:0042981 regulation of apoptotic process; GO:0050679 positive regulation of epithelial cell proliferation; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0031252 cell leading edge; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0042995 cell projection; GO:0071944 cell periphery; GO:0032587 ruffle membrane; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0005634 nucleus; GO:0098590 plasma membrane region; GO:0044459 plasma membrane part; GO:0031256 leading edge membrane; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:1903561 extracellular vesicle; GO:0031253 cell projection membrane; GO:0001726 ruffle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0019205 nucleobase-containing compound kinase activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0016776 phosphotransferase activity, phosphate group as acceptor; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0042802 identical protein binding; GO:0016301 kinase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0043024 ribosomal small subunit binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0000287 magnesium ion binding; GO:0003723 RNA binding; GO:0005524 ATP binding; GO:0004536 deoxyribonuclease activity; GO:0004550 nucleoside diphosphate kinase activity; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0004518 nuclease activity; GO:0003676 nucleic acid binding; GO:0046872 metal ion binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0032561 guanyl ribonucleotide binding; GO:0043021 ribonucleoprotein complex binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0036094 small molecule binding; ","K00940","ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]","hsa00230 Purine metabolism - Homo sapiens (human); hsa00983 Drug metabolism - other enzymes - Homo sapiens (human); hsa00240 Pyrimidine metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); "]
["P15559","NAD(P)H dehydrogenase [quinone] 1 OS=Homo sapiens OX=9606 GN=NQO1","NQO1",30.867,5.1787,6.2,2,2,2,1.291,1.23,1.285,0.749,0.757,0.731,0.588,4.44e-06,"cytoplasm\r","GO:0044700 single organism signaling; GO:0006801 superoxide metabolic process; GO:0010941 regulation of cell death; GO:0000303 response to superoxide; GO:0043523 regulation of neuron apoptotic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0019430 removal of superoxide radicals; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0007154 cell communication; GO:0006979 response to oxidative stress; GO:0007271 synaptic transmission, cholinergic; GO:0098916 anterograde trans-synaptic signaling; GO:0098869 cellular oxidant detoxification; GO:0010035 response to inorganic substance; GO:0034599 cellular response to oxidative stress; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0014070 response to organic cyclic compound; GO:0034614 cellular response to reactive oxygen species; GO:0006521 regulation of cellular amino acid metabolic process; GO:0071450 cellular response to oxygen radical; GO:0080090 regulation of primary metabolic process; GO:0055114 oxidation-reduction process; GO:0000302 response to reactive oxygen species; GO:0009636 response to toxic substance; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0031323 regulation of cellular metabolic process; GO:0043086 negative regulation of catalytic activity; GO:0010942 positive regulation of cell death; GO:0010565 regulation of cellular ketone metabolic process; GO:0043525 positive regulation of neuron apoptotic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0007267 cell-cell signaling; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0007568 aging; GO:0000305 response to oxygen radical; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0060548 negative regulation of cell death; GO:0098754 detoxification; GO:0043068 positive regulation of programmed cell death; GO:0071466 cellular response to xenobiotic stimulus; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0043069 negative regulation of programmed cell death; GO:0045471 response to ethanol; GO:1901700 response to oxygen-containing compound; GO:0043067 regulation of programmed cell death; GO:0043065 positive regulation of apoptotic process; GO:0032355 response to estradiol; GO:0046209 nitric oxide metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:0033993 response to lipid; GO:0009991 response to extracellular stimulus; GO:1990748 cellular detoxification; GO:0006805 xenobiotic metabolic process; GO:0009410 response to xenobiotic stimulus; GO:0043066 negative regulation of apoptotic process; GO:0072593 reactive oxygen species metabolic process; GO:1901216 positive regulation of neuron death; GO:0099537 trans-synaptic signaling; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:2001057 reactive nitrogen species metabolic process; GO:0009987 cellular process; GO:0033238 regulation of cellular amine metabolic process; GO:1901214 regulation of neuron death; GO:1903409 reactive oxygen species biosynthetic process; GO:0006950 response to stress; GO:0071451 cellular response to superoxide; GO:0006807 nitrogen compound metabolic process; GO:0097305 response to alcohol; GO:0010033 response to organic substance; GO:0007584 response to nutrient; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:1901701 cellular response to oxygen-containing compound; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0099536 synaptic signaling; GO:0044767 single-organism developmental process; GO:0031667 response to nutrient levels; GO:0007268 chemical synaptic transmission; GO:0006809 nitric oxide biosynthetic process; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0043025 neuronal cell body; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0036477 somatodendritic compartment; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0044297 cell body; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0004784 superoxide dismutase activity; GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:0003723 RNA binding; GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor; GO:0016721 oxidoreductase activity, acting on superoxide radicals as acceptor; GO:0003955 NAD(P)H dehydrogenase (quinone) activity; GO:0016209 antioxidant activity; GO:0005515 protein binding; GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; GO:0016491 oxidoreductase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H; ","K00355","NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]","hsa05225 Hepatocellular carcinoma - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa00130 Ubiquinone and other terpenoid-quinone biosynthesis - Homo sapiens (human); hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human); ","IPR003680; IPR029039; ","Flavodoxin-like fold; Flavoprotein-like domain; \r"]
["P15586","N-acetylglucosamine-6-sulfatase OS=Homo sapiens OX=9606 GN=GNS","GNS",62.081,22.414,10.1,5,7,5,0.988,1.114,0.97,1.01,0.965,0.986,0.964,0.483,"plasma membrane\r","GO:0045321 leukocyte activation; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0006026 aminoglycan catabolic process; GO:0044699 single-organism process; GO:0042340 keratan sulfate catabolic process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:0071704 organic substance metabolic process; GO:0030203 glycosaminoglycan metabolic process; GO:0042339 keratan sulfate metabolic process; GO:0008152 metabolic process; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:1901135 carbohydrate derivative metabolic process; GO:0044248 cellular catabolic process; GO:0036230 granulocyte activation; GO:0043170 macromolecule metabolic process; GO:0006022 aminoglycan metabolic process; GO:0009987 cellular process; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0006790 sulfur compound metabolic process; GO:0002443 leukocyte mediated immunity; GO:1903510 mucopolysaccharide metabolic process; GO:0044712 single-organism catabolic process; GO:0002446 neutrophil mediated immunity; GO:0016192 vesicle-mediated transport; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901136 carbohydrate derivative catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0002376 immune system process; GO:0043312 neutrophil degranulation; GO:0002263 cell activation involved in immune response; GO:0002444 myeloid leukocyte mediated immunity; GO:0006027 glycosaminoglycan catabolic process; GO:0006810 transport; GO:0002366 leukocyte activation involved in immune response; GO:1901575 organic substance catabolic process; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:1901565 organonitrogen compound catabolic process; GO:0032940 secretion by cell; GO:0044710 single-organism metabolic process; GO:0009057 macromolecule catabolic process; GO:0001775 cell activation; GO:0043299 leukocyte degranulation; GO:0044273 sulfur compound catabolic process; GO:0051179 localization; GO:0006955 immune response; GO:0006082 organic acid metabolic process; GO:0009056 catabolic process; GO:0043436 oxoacid metabolic process; GO:0006887 exocytosis; GO:1901564 organonitrogen compound metabolic process; ","GO:0034774 secretory granule lumen; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0043202 lysosomal lumen; GO:0042582 azurophil granule; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0008484 sulfuric ester hydrolase activity; GO:0008449 N-acetylglucosamine-6-sulfatase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0016787 hydrolase activity; GO:0005515 protein binding; ","K01137","GNS; N-acetylglucosamine-6-sulfatase [EC:3.1.6.14]","hsa04142 Lysosome - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00531 Glycosaminoglycan degradation - Homo sapiens (human); ","IPR017849; IPR000917; IPR017850; ","\"Alkaline phosphatase-like, alpha/beta/alpha; Sulfatase, N-terminal; Alkaline-phosphatase-like, core domain; \"\r"]
["P15848","Arylsulfatase B OS=Homo sapiens OX=9606 GN=ARSB","ARSB",59.687,2.6879,1.9,1,1,1,0.99,0.966,0.97,1.087,0.976,1.018,1.053,0.191,"Golgi apparatus\r","GO:0090130 tissue migration; GO:0045321 leukocyte activation; GO:0044255 cellular lipid metabolic process; GO:0006914 autophagy; GO:0044237 cellular metabolic process; GO:0030203 glycosaminoglycan metabolic process; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0051597 response to methylmercury; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0007399 nervous system development; GO:0006790 sulfur compound metabolic process; GO:0002443 leukocyte mediated immunity; GO:0010632 regulation of epithelial cell migration; GO:0031346 positive regulation of cell projection organization; GO:0048699 generation of neurons; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0009100 glycoprotein metabolic process; GO:0048870 cell motility; GO:0032501 multicellular organismal process; GO:0006027 glycosaminoglycan catabolic process; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0010631 epithelial cell migration; GO:0006029 proteoglycan metabolic process; GO:0007417 central nervous system development; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0051094 positive regulation of developmental process; GO:0010975 regulation of neuron projection development; GO:0043436 oxoacid metabolic process; GO:0043687 post-translational protein modification; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0002283 neutrophil activation involved in immune response; GO:0009628 response to abiotic stimulus; GO:0044267 cellular protein metabolic process; GO:0090132 epithelium migration; GO:0045597 positive regulation of cell differentiation; GO:0051239 regulation of multicellular organismal process; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:2000145 regulation of cell motility; GO:1901135 carbohydrate derivative metabolic process; GO:0044248 cellular catabolic process; GO:0007275 multicellular organism development; GO:0061582 intestinal epithelial cell migration; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0016192 vesicle-mediated transport; GO:1901136 carbohydrate derivative catabolic process; GO:0002376 immune system process; GO:0030334 regulation of cell migration; GO:0010033 response to organic substance; GO:0007584 response to nutrient; GO:0044238 primary metabolic process; GO:0002263 cell activation involved in immune response; GO:0045055 regulated exocytosis; GO:0010976 positive regulation of neuron projection development; GO:0006996 organelle organization; GO:0006928 movement of cell or subcellular component; GO:0080171 lytic vacuole organization; GO:0001775 cell activation; GO:0050769 positive regulation of neurogenesis; GO:0006955 immune response; GO:0043412 macromolecule modification; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0006887 exocytosis; GO:1901564 organonitrogen compound metabolic process; GO:0045666 positive regulation of neuron differentiation; GO:0051674 localization of cell; GO:0043627 response to estrogen; GO:0006643 membrane lipid metabolic process; GO:0006026 aminoglycan catabolic process; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0030207 chondroitin sulfate catabolic process; GO:0030204 chondroitin sulfate metabolic process; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0006665 sphingolipid metabolic process; GO:0007033 vacuole organization; GO:0010720 positive regulation of cell development; GO:0006629 lipid metabolic process; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:0002446 neutrophil mediated immunity; GO:0051962 positive regulation of nervous system development; GO:0006664 glycolipid metabolic process; GO:0048522 positive regulation of cellular process; GO:0002444 myeloid leukocyte mediated immunity; GO:0007040 lysosome organization; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0061580 colon epithelial cell migration; GO:0045664 regulation of neuron differentiation; GO:0032940 secretion by cell; GO:0001667 ameboidal-type cell migration; GO:0044273 sulfur compound catabolic process; GO:0043299 leukocyte degranulation; GO:0040011 locomotion; GO:0036211 protein modification process; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0016043 cellular component organization; GO:0016477 cell migration; GO:1903509 liposaccharide metabolic process; GO:0002252 immune effector process; GO:0006687 glycosphingolipid metabolic process; GO:0031344 regulation of cell projection organization; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0009991 response to extracellular stimulus; GO:0009268 response to pH; GO:0030154 cell differentiation; GO:0050654 chondroitin sulfate proteoglycan metabolic process; GO:0036230 granulocyte activation; GO:0006022 aminoglycan metabolic process; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0007041 lysosomal transport; GO:1903510 mucopolysaccharide metabolic process; GO:0044712 single-organism catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:1901565 organonitrogen compound catabolic process; GO:0044767 single-organism developmental process; GO:0007034 vacuolar transport; GO:0009057 macromolecule catabolic process; GO:0051128 regulation of cellular component organization; GO:0031667 response to nutrient levels; GO:0040012 regulation of locomotion; GO:0009056 catabolic process; GO:0050767 regulation of neurogenesis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0034774 secretory granule lumen; GO:0005783 endoplasmic reticulum; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0005788 endoplasmic reticulum lumen; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0005791 rough endoplasmic reticulum; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0043202 lysosomal lumen; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0042582 azurophil granule; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0044432 endoplasmic reticulum part; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0009986 cell surface; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0004065 arylsulfatase activity; GO:0008484 sulfuric ester hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0016787 hydrolase activity; GO:0003943 N-acetylgalactosamine-4-sulfatase activity; ","K01135","ARSB; arylsulfatase B [EC:3.1.6.12]","hsa04142 Lysosome - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00531 Glycosaminoglycan degradation - Homo sapiens (human); ","IPR017849; IPR000917; IPR017850; ","\"Alkaline phosphatase-like, alpha/beta/alpha; Sulfatase, N-terminal; Alkaline-phosphatase-like, core domain; \"\r"]
["P15880","40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2","RPS2",31.324,88.3,39.6,12,24,12,0.853,0.823,0.873,1.093,1.136,1.186,1.34,0.000559,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0072594 establishment of protein localization to organelle; GO:0006518 peptide metabolic process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0032259 methylation; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0008213 protein alkylation; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0051649 establishment of localization in cell; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0070972 protein localization to endoplasmic reticulum; GO:0006364 rRNA processing; GO:0044093 positive regulation of molecular function; GO:0006413 translational initiation; GO:1901361 organic cyclic compound catabolic process; GO:0051347 positive regulation of transferase activity; GO:0033365 protein localization to organelle; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0006412 translation; GO:0016072 rRNA metabolic process; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0072657 protein localization to membrane; GO:0043043 peptide biosynthetic process; GO:0042254 ribosome biogenesis; GO:1901360 organic cyclic compound metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032774 RNA biosynthetic process; GO:0045047 protein targeting to ER; GO:0043603 cellular amide metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0006401 RNA catabolic process; GO:0016070 RNA metabolic process; GO:0019439 aromatic compound catabolic process; GO:1901575 organic substance catabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0050790 regulation of catalytic activity; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0006464 cellular protein modification process; GO:0019083 viral transcription; GO:0036211 protein modification process; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0046907 intracellular transport; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0044267 cellular protein metabolic process; GO:0006613 cotranslational protein targeting to membrane; GO:0048519 negative regulation of biological process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0006479 protein methylation; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0016032 viral process; GO:0019080 viral gene expression; GO:0051338 regulation of transferase activity; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0006886 intracellular protein transport; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0034613 cellular protein localization; GO:0009059 macromolecule biosynthetic process; GO:0090150 establishment of protein localization to membrane; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0043085 positive regulation of catalytic activity; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0043414 macromolecule methylation; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0051179 localization; GO:0043412 macromolecule modification; GO:0009056 catabolic process; GO:0034660 ncRNA metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0030054 cell junction; GO:0031982 vesicle; GO:0015935 small ribosomal subunit; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0005925 focal adhesion; GO:0070013 intracellular organelle lumen; GO:0044391 ribosomal subunit; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0044445 cytosolic part; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0022626 cytosolic ribosome; GO:0043229 intracellular organelle; GO:0005840 ribosome; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0022627 cytosolic small ribosomal subunit; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0050839 cell adhesion molecule binding; GO:0003729 mRNA binding; GO:0003723 RNA binding; GO:0019838 growth factor binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0017134 fibroblast growth factor binding; GO:0005198 structural molecule activity; GO:0003735 structural constituent of ribosome; GO:0019899 enzyme binding; ","K02981","RP-S2e; small subunit ribosomal protein S2e","hsa03010 Ribosome - Homo sapiens (human); ","IPR014720; IPR020568; IPR005324; IPR014721; IPR013810; ","\"Double-stranded RNA-binding domain; Ribosomal protein S5 domain 2-type fold; Ribosomal protein S5, C-terminal; Ribosomal protein S5 domain 2-type fold, subgroup; Ribosomal protein S5, N-terminal; \"\r"]
["P15884","Transcription factor 4 OS=Homo sapiens OX=9606 GN=TCF4","TCF4",71.307,2.5413,1.3,1,1,1,0.977,1.097,0.901,1.046,0.938,1.053,1.021,0.758,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0045666 positive regulation of neuron differentiation; GO:0097659 nucleic acid-templated transcription; GO:0048869 cellular developmental process; GO:0009891 positive regulation of biosynthetic process; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0022607 cellular component assembly; GO:0009893 positive regulation of metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0065003 macromolecular complex assembly; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0043170 macromolecule metabolic process; GO:0010720 positive regulation of cell development; GO:0071824 protein-DNA complex subunit organization; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0045893 positive regulation of transcription, DNA-templated; GO:0051962 positive regulation of nervous system development; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0065004 protein-DNA complex assembly; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0045664 regulation of neuron differentiation; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0048856 anatomical structure development; GO:0051094 positive regulation of developmental process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:2000026 regulation of multicellular organismal development; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0006352 DNA-templated transcription, initiation; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0045597 positive regulation of cell differentiation; GO:0051239 regulation of multicellular organismal process; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0007275 multicellular organism development; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006367 transcription initiation from RNA polymerase II promoter; GO:0045595 regulation of cell differentiation; GO:0034622 cellular macromolecular complex assembly; GO:0051254 positive regulation of RNA metabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0048731 system development; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044767 single-organism developmental process; GO:0006366 transcription from RNA polymerase II promoter; GO:0031325 positive regulation of cellular metabolic process; GO:0010467 gene expression; GO:0050769 positive regulation of neurogenesis; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0050793 regulation of developmental process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:0050767 regulation of neurogenesis; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005667 transcription factor complex; GO:0005623 cell; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0000785 chromatin; GO:0044454 nuclear chromosome part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0000790 nuclear chromatin; GO:0000228 nuclear chromosome; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding; GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding; GO:0003690 double-stranded DNA binding; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:0000987 core promoter proximal region sequence-specific DNA binding; GO:0003700 transcription factor activity, sequence-specific DNA binding; GO:0000975 regulatory region DNA binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding; GO:0070888 E-box binding; GO:0042802 identical protein binding; GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting; GO:0005488 binding; GO:0001085 RNA polymerase II transcription factor binding; GO:0001071 nucleic acid binding transcription factor activity; GO:0000989 transcription factor activity, transcription factor binding; GO:0008022 protein C-terminus binding; GO:0043425 bHLH transcription factor binding; GO:0001087 transcription factor activity, TFIIB-class binding; GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding; GO:0003677 DNA binding; GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding; GO:0001099 basal RNA polymerase II transcription machinery binding; GO:0046982 protein heterodimerization activity; GO:0001093 TFIIB-class transcription factor binding; GO:0000976 transcription regulatory region sequence-specific DNA binding; GO:0001012 RNA polymerase II regulatory region DNA binding; GO:1990837 sequence-specific double-stranded DNA binding; GO:0043565 sequence-specific DNA binding; GO:0001083 transcription factor activity, RNA polymerase II basal transcription factor binding; GO:0001159 core promoter proximal region DNA binding; GO:0001067 regulatory region nucleic acid binding; GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding; GO:0001098 basal transcription machinery binding; GO:0042803 protein homodimerization activity; GO:0044212 transcription regulatory region DNA binding; GO:0003676 nucleic acid binding; GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding; GO:0001091 RNA polymerase II basal transcription factor binding; GO:0000988 transcription factor activity, protein binding; GO:0008134 transcription factor binding; ","K15603",null,null,"IPR011598; ","\"Myc-type, basic helix-loop-helix (bHLH) domain; \"\r"]
["P15924","Desmoplakin OS=Homo sapiens OX=9606 GN=DSP","DSP",331.77,323.31,36.5,99,139,99,0.924,0.923,0.932,1.077,1.074,1.089,1.166,4.02e-06,"nucleus\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0071896 protein localization to adherens junction; GO:0031424 keratinization; GO:0060415 muscle tissue morphogenesis; GO:0044237 cellular metabolic process; GO:0022610 biological adhesion; GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication; GO:0061337 cardiac conduction; GO:0009913 epidermal cell differentiation; GO:0008152 metabolic process; GO:0098900 regulation of action potential; GO:0007507 heart development; GO:0032879 regulation of localization; GO:0003208 cardiac ventricle morphogenesis; GO:1903115 regulation of actin filament-based movement; GO:0034332 adherens junction organization; GO:0007155 cell adhesion; GO:0044057 regulation of system process; GO:0008544 epidermis development; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0008104 protein localization; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0002443 leukocyte mediated immunity; GO:0043588 skin development; GO:0060537 muscle tissue development; GO:0070268 cornification; GO:0055008 cardiac muscle tissue morphogenesis; GO:0044763 single-organism cellular process; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:0048513 animal organ development; GO:0003229 ventricular cardiac muscle tissue development; GO:0098602 single organism cell adhesion; GO:0048644 muscle organ morphogenesis; GO:0044260 cellular macromolecule metabolic process; GO:0009887 animal organ morphogenesis; GO:0006464 cellular protein modification process; GO:0097435 supramolecular fiber organization; GO:0030855 epithelial cell differentiation; GO:0050794 regulation of cellular process; GO:0072359 circulatory system development; GO:0044707 single-multicellular organism process; GO:0002283 neutrophil activation involved in immune response; GO:0044267 cellular protein metabolic process; GO:0018149 peptide cross-linking; GO:0086042 cardiac muscle cell-cardiac muscle cell adhesion; GO:0003223 ventricular compact myocardium morphogenesis; GO:0034109 homotypic cell-cell adhesion; GO:0051239 regulation of multicellular organismal process; GO:0009653 anatomical structure morphogenesis; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0055010 ventricular cardiac muscle tissue morphogenesis; GO:0061061 muscle structure development; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0003231 cardiac ventricle development; GO:0045104 intermediate filament cytoskeleton organization; GO:0006950 response to stress; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0045103 intermediate filament-based process; GO:0002376 immune system process; GO:0032970 regulation of actin filament-based process; GO:0044238 primary metabolic process; GO:0003206 cardiac chamber morphogenesis; GO:0002263 cell activation involved in immune response; GO:0045055 regulated exocytosis; GO:0006996 organelle organization; GO:0002027 regulation of heart rate; GO:0001775 cell activation; GO:0012501 programmed cell death; GO:0006955 immune response; GO:0051179 localization; GO:0043412 macromolecule modification; GO:0006887 exocytosis; GO:0045109 intermediate filament organization; GO:0086069 bundle of His cell to Purkinje myocyte communication; GO:0048869 cellular developmental process; GO:0045216 cell-cell junction organization; GO:0044699 single-organism process; GO:0034113 heterotypic cell-cell adhesion; GO:0098901 regulation of cardiac muscle cell action potential; GO:0051234 establishment of localization; GO:0009611 response to wounding; GO:0048729 tissue morphogenesis; GO:0016337 single organismal cell-cell adhesion; GO:0007154 cell communication; GO:0055117 regulation of cardiac muscle contraction; GO:0033036 macromolecule localization; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0098911 regulation of ventricular cardiac muscle cell action potential; GO:0030216 keratinocyte differentiation; GO:0009888 tissue development; GO:0002934 desmosome organization; GO:0002446 neutrophil mediated immunity; GO:0003007 heart morphogenesis; GO:0035637 multicellular organismal signaling; GO:0098609 cell-cell adhesion; GO:0090257 regulation of muscle system process; GO:0023052 signaling; GO:0002444 myeloid leukocyte mediated immunity; GO:0006942 regulation of striated muscle contraction; GO:0042391 regulation of membrane potential; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0007517 muscle organ development; GO:0032940 secretion by cell; GO:0043299 leukocyte degranulation; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0014706 striated muscle tissue development; GO:0016043 cellular component organization; GO:0048738 cardiac muscle tissue development; GO:0002252 immune effector process; GO:1903522 regulation of blood circulation; GO:0008016 regulation of heart contraction; GO:0050896 response to stimulus; GO:0086004 regulation of cardiac muscle cell contraction; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0086091 regulation of heart rate by cardiac conduction; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0006937 regulation of muscle contraction; GO:0043312 neutrophil degranulation; GO:0003205 cardiac chamber development; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0042060 wound healing; GO:0034330 cell junction organization; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:1902414 protein localization to cell junction; GO:0071840 cellular component organization or biogenesis; GO:0086065 cell communication involved in cardiac conduction; GO:0065007 biological regulation; ","GO:0016323 basolateral plasma membrane; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0044291 cell-cell contact zone; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0005913 cell-cell adherens junction; GO:0099080 supramolecular complex; GO:0005911 cell-cell junction; GO:0005623 cell; GO:0044422 organelle part; GO:0014704 intercalated disc; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0098590 plasma membrane region; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0098805 whole membrane; GO:0099503 secretory vesicle; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0005916 fascia adherens; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0070820 tertiary granule; GO:0070161 anchoring junction; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0099081 supramolecular polymer; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0030057 desmosome; GO:0043231 intracellular membrane-bounded organelle; GO:0031012 extracellular matrix; GO:0043226 organelle; GO:0030667 secretory granule membrane; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0045111 intermediate filament cytoskeleton; GO:0001533 cornified envelope; GO:0101003 ficolin-1-rich granule membrane; GO:0005882 intermediate filament; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0003723 RNA binding; GO:0030674 protein binding, bridging; GO:0019901 protein kinase binding; GO:0097110 scaffold protein binding; GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication; GO:0005515 protein binding; GO:0019900 kinase binding; GO:0098632 protein binding involved in cell-cell adhesion; GO:0086080 protein binding involved in heterotypic cell-cell adhesion; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0050839 cell adhesion molecule binding; GO:0098631 protein binding involved in cell adhesion; GO:0005200 structural constituent of cytoskeleton; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005080 protein kinase C binding; GO:0060090 binding, bridging; GO:0005198 structural molecule activity; GO:0019899 enzyme binding; ","K10381","DSP; desmoplakin","hsa05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human); "]
["P15927","Replication protein A 32 kDa subunit OS=Homo sapiens OX=9606 GN=RPA2","RPA2",29.247,6.3768,8.1,2,4,2,0.968,0.897,0.883,1.041,1.112,1.096,1.182,0.00844,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:1902807 negative regulation of cell cycle G1/S phase transition; GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion; GO:0006289 nucleotide-excision repair; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0065003 macromolecular complex assembly; GO:0051606 detection of stimulus; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0019985 translesion synthesis; GO:0044770 cell cycle phase transition; GO:0043170 macromolecule metabolic process; GO:0033365 protein localization to organelle; GO:0008104 protein localization; GO:0000018 regulation of DNA recombination; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0044773 mitotic DNA damage checkpoint; GO:0080090 regulation of primary metabolic process; GO:2000134 negative regulation of G1/S transition of mitotic cell cycle; GO:0044763 single-organism cellular process; GO:0031323 regulation of cellular metabolic process; GO:0065004 protein-DNA complex assembly; GO:0010948 negative regulation of cell cycle process; GO:0080135 regulation of cellular response to stress; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0032200 telomere organization; GO:0006297 nucleotide-excision repair, DNA gap filling; GO:0006312 mitotic recombination; GO:0090305 nucleic acid phosphodiester bond hydrolysis; GO:1901362 organic cyclic compound biosynthetic process; GO:0034502 protein localization to chromosome; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0007346 regulation of mitotic cell cycle; GO:0006260 DNA replication; GO:0006283 transcription-coupled nucleotide-excision repair; GO:2001020 regulation of response to DNA damage stimulus; GO:0006259 DNA metabolic process; GO:0000731 DNA synthesis involved in DNA repair; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:1903047 mitotic cell cycle process; GO:0060249 anatomical structure homeostasis; GO:0006301 postreplication repair; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901987 regulation of cell cycle phase transition; GO:0044819 mitotic G1/S transition checkpoint; GO:0007093 mitotic cell cycle checkpoint; GO:0070987 error-free translesion synthesis; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034613 cellular protein localization; GO:0009966 regulation of signal transduction; GO:0044772 mitotic cell cycle phase transition; GO:1902531 regulation of intracellular signal transduction; GO:0006950 response to stress; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0044238 primary metabolic process; GO:0036297 interstrand cross-link repair; GO:1901576 organic substance biosynthetic process; GO:0006974 cellular response to DNA damage stimulus; GO:0000725 recombinational repair; GO:0051276 chromosome organization; GO:0006996 organelle organization; GO:0006294 nucleotide-excision repair, preincision complex assembly; GO:0051179 localization; GO:0000723 telomere maintenance; GO:2000045 regulation of G1/S transition of mitotic cell cycle; GO:0010569 regulation of double-strand break repair via homologous recombination; GO:0023051 regulation of signaling; GO:0044783 G1 DNA damage checkpoint; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0006282 regulation of DNA repair; GO:0051130 positive regulation of cellular component organization; GO:0045930 negative regulation of mitotic cell cycle; GO:0010646 regulation of cell communication; GO:0000077 DNA damage checkpoint; GO:0044774 mitotic DNA integrity checkpoint; GO:0022607 cellular component assembly; GO:1901991 negative regulation of mitotic cell cycle phase transition; GO:1902806 regulation of cell cycle G1/S phase transition; GO:0000075 cell cycle checkpoint; GO:0031334 positive regulation of protein complex assembly; GO:0033036 macromolecule localization; GO:0051726 regulation of cell cycle; GO:0006310 DNA recombination; GO:0071824 protein-DNA complex subunit organization; GO:0031571 mitotic G1 DNA damage checkpoint; GO:0031570 DNA integrity checkpoint; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0000722 telomere maintenance via recombination; GO:0006298 mismatch repair; GO:0050789 regulation of biological process; GO:0043254 regulation of protein complex assembly; GO:2000001 regulation of DNA damage checkpoint; GO:0090304 nucleic acid metabolic process; GO:0051052 regulation of DNA metabolic process; GO:0042276 error-prone translesion synthesis; GO:1900034 regulation of cellular response to heat; GO:0019222 regulation of metabolic process; GO:0016043 cellular component organization; GO:0045786 negative regulation of cell cycle; GO:0006725 cellular aromatic compound metabolic process; GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion; GO:1901988 negative regulation of cell cycle phase transition; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0006302 double-strand break repair; GO:0044087 regulation of cellular component biogenesis; GO:0042769 DNA damage response, detection of DNA damage; GO:0050896 response to stimulus; GO:0006293 nucleotide-excision repair, preincision complex stabilization; GO:0033683 nucleotide-excision repair, DNA incision; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:1901796 regulation of signal transduction by p53 class mediator; GO:0034641 cellular nitrogen compound metabolic process; GO:0071897 DNA biosynthetic process; GO:0009059 macromolecule biosynthetic process; GO:0000082 G1/S transition of mitotic cell cycle; GO:0009987 cellular process; GO:0000724 double-strand break repair via homologous recombination; GO:0034622 cellular macromolecular complex assembly; GO:0006284 base-excision repair; GO:1901976 regulation of cell cycle checkpoint; GO:0044843 cell cycle G1/S phase transition; GO:0006807 nitrogen compound metabolic process; GO:2000779 regulation of double-strand break repair; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0051641 cellular localization; GO:0006281 DNA repair; GO:0070727 cellular macromolecule localization; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0051128 regulation of cellular component organization; GO:0022402 cell cycle process; GO:0044089 positive regulation of cellular component biogenesis; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0000784 nuclear chromosome, telomeric region; GO:0000781 chromosome, telomeric region; GO:0043601 nuclear replisome; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0016605 PML body; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044454 nuclear chromosome part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0030894 replisome; GO:0043227 membrane-bounded organelle; GO:0032993 protein-DNA complex; GO:0044451 nucleoplasm part; GO:0005662 DNA replication factor A complex; GO:0043233 organelle lumen; GO:0005657 replication fork; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0043596 nuclear replication fork; GO:0043226 organelle; GO:0098687 chromosomal region; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0000785 chromatin; GO:0000228 nuclear chromosome; GO:0043234 protein complex; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003677 DNA binding; GO:0047485 protein N-terminus binding; GO:0019903 protein phosphatase binding; GO:0031625 ubiquitin protein ligase binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0003697 single-stranded DNA binding; GO:0003684 damaged DNA binding; GO:0005515 protein binding; GO:0019902 phosphatase binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0019899 enzyme binding; ","K10739","RFA2; replication factor A2","hsa03460 Fanconi anemia pathway - Homo sapiens (human); hsa03430 Mismatch repair - Homo sapiens (human); hsa03440 Homologous recombination - Homo sapiens (human); hsa03420 Nucleotide excision repair - Homo sapiens (human); hsa03030 DNA replication - Homo sapiens (human); ","IPR011991; IPR012340; IPR014892; ","\"Winged helix-turn-helix DNA-binding domain; Nucleic acid-binding, OB-fold; Replication protein A, C-terminal; \"\r"]
["P15941","Mucin-1 OS=Homo sapiens OX=9606 GN=MUC1","MUC1",122.1,3.1501,0.9,1,2,1,1.133,1.217,1.237,0.782,0.87,0.792,0.681,0.000878,"extracellular\r","GO:0044700 single organism signaling; GO:0043413 macromolecule glycosylation; GO:1902807 negative regulation of cell cycle G1/S phase transition; GO:0010941 regulation of cell death; GO:0032270 positive regulation of cellular protein metabolic process; GO:0002220 innate immune response activating cell surface receptor signaling pathway; GO:0007166 cell surface receptor signaling pathway; GO:0009891 positive regulation of biosynthetic process; GO:0031347 regulation of defense response; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0042772 DNA damage response, signal transduction resulting in transcription; GO:1905269 positive regulation of chromatin organization; GO:0072431 signal transduction involved in mitotic G1 DNA damage checkpoint; GO:1902403 signal transduction involved in mitotic DNA integrity checkpoint; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:1902165 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; GO:1901990 regulation of mitotic cell cycle phase transition; GO:1902229 regulation of intrinsic apoptotic signaling pathway in response to DNA damage; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0090068 positive regulation of cell cycle process; GO:0000278 mitotic cell cycle; GO:0006486 protein glycosylation; GO:0051716 cellular response to stimulus; GO:0044773 mitotic DNA damage checkpoint; GO:0002758 innate immune response-activating signal transduction; GO:0080090 regulation of primary metabolic process; GO:2000134 negative regulation of G1/S transition of mitotic cell cycle; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044763 single-organism cellular process; GO:0009100 glycoprotein metabolic process; GO:0031323 regulation of cellular metabolic process; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0050776 regulation of immune response; GO:1903506 regulation of nucleic acid-templated transcription; GO:2001021 negative regulation of response to DNA damage stimulus; GO:0010948 negative regulation of cell cycle process; GO:0072413 signal transduction involved in mitotic cell cycle checkpoint; GO:1902532 negative regulation of intracellular signal transduction; GO:0080135 regulation of cellular response to stress; GO:0002223 stimulatory C-type lectin receptor signaling pathway; GO:1902400 intracellular signal transduction involved in G1 DNA damage checkpoint; GO:1902253 regulation of intrinsic apoptotic signaling pathway by p53 class mediator; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:2001252 positive regulation of chromosome organization; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0002682 regulation of immune system process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0060548 negative regulation of cell death; GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0007346 regulation of mitotic cell cycle; GO:0090239 regulation of histone H4 acetylation; GO:0007162 negative regulation of cell adhesion; GO:2001020 regulation of response to DNA damage stimulus; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0031399 regulation of protein modification process; GO:0043067 regulation of programmed cell death; GO:0044267 cellular protein metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:1903047 mitotic cell cycle process; GO:0030330 DNA damage response, signal transduction by p53 class mediator; GO:0045892 negative regulation of transcription, DNA-templated; GO:1901985 positive regulation of protein acetylation; GO:0023057 negative regulation of signaling; GO:0031349 positive regulation of defense response; GO:0010648 negative regulation of cell communication; GO:1902402 signal transduction involved in mitotic DNA damage checkpoint; GO:1901987 regulation of cell cycle phase transition; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0044819 mitotic G1/S transition checkpoint; GO:0007093 mitotic cell cycle checkpoint; GO:0043620 regulation of DNA-templated transcription in response to stress; GO:1901135 carbohydrate derivative metabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0009966 regulation of signal transduction; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0050778 positive regulation of immune response; GO:0045787 positive regulation of cell cycle; GO:1901797 negative regulation of signal transduction by p53 class mediator; GO:0002253 activation of immune response; GO:0051254 positive regulation of RNA metabolic process; GO:1902531 regulation of intracellular signal transduction; GO:0006950 response to stress; GO:0072331 signal transduction by p53 class mediator; GO:1902275 regulation of chromatin organization; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress; GO:0033044 regulation of chromosome organization; GO:0006974 cellular response to DNA damage stimulus; GO:0030155 regulation of cell adhesion; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:2000758 positive regulation of peptidyl-lysine acetylation; GO:0009890 negative regulation of biosynthetic process; GO:0051247 positive regulation of protein metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0043412 macromolecule modification; GO:0031328 positive regulation of cellular biosynthetic process; GO:0048584 positive regulation of response to stimulus; GO:2000045 regulation of G1/S transition of mitotic cell cycle; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0044783 G1 DNA damage checkpoint; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0051253 negative regulation of RNA metabolic process; GO:0051130 positive regulation of cellular component organization; GO:2001141 regulation of RNA biosynthetic process; GO:2001233 regulation of apoptotic signaling pathway; GO:0045930 negative regulation of mitotic cell cycle; GO:0007165 signal transduction; GO:0000077 DNA damage checkpoint; GO:0010646 regulation of cell communication; GO:0044774 mitotic DNA integrity checkpoint; GO:0007154 cell communication; GO:2001243 negative regulation of intrinsic apoptotic signaling pathway; GO:1901991 negative regulation of mitotic cell cycle phase transition; GO:0045088 regulation of innate immune response; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:1902806 regulation of cell cycle G1/S phase transition; GO:0016266 O-glycan processing; GO:0000075 cell cycle checkpoint; GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0051726 regulation of cell cycle; GO:0090240 positive regulation of histone H4 acetylation; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0031571 mitotic G1 DNA damage checkpoint; GO:0010944 negative regulation of transcription by competitive promoter binding; GO:0010468 regulation of gene expression; GO:0009101 glycoprotein biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0031570 DNA integrity checkpoint; GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage; GO:0048522 positive regulation of cellular process; GO:0035066 positive regulation of histone acetylation; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0033629 negative regulation of cell adhesion mediated by integrin; GO:0010638 positive regulation of organelle organization; GO:0036003 positive regulation of transcription from RNA polymerase II promoter in response to stress; GO:1902679 negative regulation of RNA biosynthetic process; GO:1901983 regulation of protein acetylation; GO:0019222 regulation of metabolic process; GO:0006493 protein O-linked glycosylation; GO:0036211 protein modification process; GO:0072401 signal transduction involved in DNA integrity checkpoint; GO:2000756 regulation of peptidyl-lysine acetylation; GO:0031056 regulation of histone modification; GO:0045786 negative regulation of cell cycle; GO:0072395 signal transduction involved in cell cycle checkpoint; GO:0002218 activation of innate immune response; GO:0043069 negative regulation of programmed cell death; GO:1901988 negative regulation of cell cycle phase transition; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0035065 regulation of histone acetylation; GO:0031058 positive regulation of histone modification; GO:0043066 negative regulation of apoptotic process; GO:1901796 regulation of signal transduction by p53 class mediator; GO:0002757 immune response-activating signal transduction; GO:0042770 signal transduction in response to DNA damage; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0070085 glycosylation; GO:0071156 regulation of cell cycle arrest; GO:0006355 regulation of transcription, DNA-templated; GO:0045089 positive regulation of innate immune response; GO:0072422 signal transduction involved in DNA damage checkpoint; GO:0035556 intracellular signal transduction; GO:0010629 negative regulation of gene expression; GO:0033628 regulation of cell adhesion mediated by integrin; GO:0031401 positive regulation of protein modification process; GO:0033043 regulation of organelle organization; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0051246 regulation of protein metabolic process; GO:2001242 regulation of intrinsic apoptotic signaling pathway; GO:0002684 positive regulation of immune system process; GO:0071158 positive regulation of cell cycle arrest; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0051128 regulation of cellular component organization; GO:0022402 cell cycle process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; GO:0007049 cell cycle; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0016324 apical plasma membrane; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0098590 plasma membrane region; GO:0044454 nuclear chromosome part; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0005694 chromosome; GO:0000790 nuclear chromatin; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0043227 membrane-bounded organelle; GO:0045177 apical part of cell; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0031226 intrinsic component of plasma membrane; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0005796 Golgi lumen; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0000785 chromatin; GO:0000228 nuclear chromosome; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0003677 DNA binding; GO:0000976 transcription regulatory region sequence-specific DNA binding; GO:0003690 double-stranded DNA binding; GO:1990837 sequence-specific double-stranded DNA binding; GO:0001012 RNA polymerase II regulatory region DNA binding; GO:0005515 protein binding; GO:0043565 sequence-specific DNA binding; GO:0003712 transcription cofactor activity; GO:0000987 core promoter proximal region sequence-specific DNA binding; GO:1901363 heterocyclic compound binding; GO:0001159 core promoter proximal region DNA binding; GO:0097159 organic cyclic compound binding; GO:0000975 regulatory region DNA binding; GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding; GO:0001067 regulatory region nucleic acid binding; GO:0002039 p53 binding; GO:0044212 transcription regulatory region DNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding; GO:0000988 transcription factor activity, protein binding; ","K06568",null,null,"IPR000082; ","SEA domain; \r"]
["P15954","Cytochrome c oxidase subunit 7C, mitochondrial OS=Homo sapiens OX=9606 GN=COX7C","COX7C",7.2454,6.6845,28.6,2,3,2,1.025,0.9,0.923,1.029,1.133,1.069,1.134,0.0595,"mitochondria\r","GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0006123 mitochondrial electron transport, cytochrome c to oxygen; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0006753 nucleoside phosphate metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0044765 single-organism transport; GO:0098655 cation transmembrane transport; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006119 oxidative phosphorylation; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0006810 transport; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0022900 electron transport chain; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0098662 inorganic cation transmembrane transport; GO:0016310 phosphorylation; GO:0034220 ion transmembrane transport; GO:0006725 cellular aromatic compound metabolic process; GO:0042773 ATP synthesis coupled electron transport; GO:0009259 ribonucleotide metabolic process; GO:0022904 respiratory electron transport chain; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:1902578 single-organism localization; GO:0006139 nucleobase-containing compound metabolic process; GO:0006812 cation transport; GO:1902600 hydrogen ion transmembrane transport; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009119 ribonucleoside metabolic process; GO:0009987 cellular process; GO:0046034 ATP metabolic process; GO:0098660 inorganic ion transmembrane transport; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0045333 cellular respiration; GO:0006163 purine nucleotide metabolic process; GO:0006818 hydrogen transport; GO:0015992 proton transport; GO:0046128 purine ribonucleoside metabolic process; GO:0055085 transmembrane transport; GO:0006793 phosphorus metabolic process; GO:0006811 ion transport; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0051179 localization; GO:0015672 monovalent inorganic cation transport; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0098803 respiratory chain complex; GO:0005751 mitochondrial respiratory chain complex IV; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0070069 cytochrome complex; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0016021 integral component of membrane; GO:0005739 mitochondrion; GO:0005746 mitochondrial respiratory chain; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0045277 respiratory chain complex IV; GO:0031975 envelope; GO:0043234 protein complex; GO:0070469 respiratory chain; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0015075 ion transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0015077 monovalent inorganic cation transmembrane transporter activity; GO:0016676 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor; GO:0016675 oxidoreductase activity, acting on a heme group of donors; GO:0015078 hydrogen ion transmembrane transporter activity; GO:0015002 heme-copper terminal oxidase activity; GO:0016491 oxidoreductase activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0009055 electron carrier activity; GO:0004129 cytochrome-c oxidase activity; GO:0003824 catalytic activity; GO:0022890 inorganic cation transmembrane transporter activity; GO:0008324 cation transmembrane transporter activity; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; ","K02272","COX7C; cytochrome c oxidase subunit 7c","hsa04260 Cardiac muscle contraction - Homo sapiens (human); hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); "]
["P16035","Metalloproteinase inhibitor 2 OS=Homo sapiens OX=9606 GN=TIMP2","TIMP2",24.399,6.3738,14.5,3,5,3,1.154,1.169,1.238,0.8,0.804,0.865,0.693,0.000382,"extracellular\r","GO:0051349 positive regulation of lyase activity; GO:0032270 positive regulation of cellular protein metabolic process; GO:0045321 leukocyte activation; GO:0009891 positive regulation of biosynthetic process; GO:0008285 negative regulation of cell proliferation; GO:0010466 negative regulation of peptidase activity; GO:0030810 positive regulation of nucleotide biosynthetic process; GO:0051240 positive regulation of multicellular organismal process; GO:0044093 positive regulation of molecular function; GO:0009719 response to endogenous stimulus; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0051056 regulation of small GTPase mediated signal transduction; GO:1900373 positive regulation of purine nucleotide biosynthetic process; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0052548 regulation of endopeptidase activity; GO:0007399 nervous system development; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0002443 leukocyte mediated immunity; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0048699 generation of neurons; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0031323 regulation of cellular metabolic process; GO:0043086 negative regulation of catalytic activity; GO:0032501 multicellular organismal process; GO:0051339 regulation of lyase activity; GO:0006810 transport; GO:0031279 regulation of cyclase activity; GO:0032487 regulation of Rap protein signal transduction; GO:1902532 negative regulation of intracellular signal transduction; GO:0051336 regulation of hydrolase activity; GO:0007417 central nervous system development; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0010604 positive regulation of macromolecule metabolic process; GO:0045981 positive regulation of nucleotide metabolic process; GO:0051094 positive regulation of developmental process; GO:0006140 regulation of nucleotide metabolic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0007346 regulation of mitotic cell cycle; GO:0010951 negative regulation of endopeptidase activity; GO:0002283 neutrophil activation involved in immune response; GO:0042127 regulation of cell proliferation; GO:0030801 positive regulation of cyclic nucleotide metabolic process; GO:0031399 regulation of protein modification process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0051239 regulation of multicellular organismal process; GO:0045597 positive regulation of cell differentiation; GO:0042493 response to drug; GO:0023057 negative regulation of signaling; GO:0045761 regulation of adenylate cyclase activity; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0010648 negative regulation of cell communication; GO:0051043 regulation of membrane protein ectodomain proteolysis; GO:0009889 regulation of biosynthetic process; GO:0043062 extracellular structure organization; GO:0030817 regulation of cAMP biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0042176 regulation of protein catabolic process; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:0046580 negative regulation of Ras protein signal transduction; GO:0045861 negative regulation of proteolysis; GO:1902531 regulation of intracellular signal transduction; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0030162 regulation of proteolysis; GO:0030799 regulation of cyclic nucleotide metabolic process; GO:0002263 cell activation involved in immune response; GO:0009892 negative regulation of metabolic process; GO:0031330 negative regulation of cellular catabolic process; GO:0045055 regulated exocytosis; GO:0051247 positive regulation of protein metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0001775 cell activation; GO:0050769 positive regulation of neurogenesis; GO:0048584 positive regulation of response to stimulus; GO:0031328 positive regulation of cellular biosynthetic process; GO:0051179 localization; GO:0006955 immune response; GO:0051045 negative regulation of membrane protein ectodomain proteolysis; GO:0050793 regulation of developmental process; GO:0006887 exocytosis; GO:0045666 positive regulation of neuron differentiation; GO:0009968 negative regulation of signal transduction; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0030819 positive regulation of cAMP biosynthetic process; GO:0051234 establishment of localization; GO:0045930 negative regulation of mitotic cell cycle; GO:0010646 regulation of cell communication; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0030814 regulation of cAMP metabolic process; GO:0022617 extracellular matrix disassembly; GO:0030198 extracellular matrix organization; GO:0010720 positive regulation of cell development; GO:0051726 regulation of cell cycle; GO:0030808 regulation of nucleotide biosynthetic process; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:0030802 regulation of cyclic nucleotide biosynthetic process; GO:0045937 positive regulation of phosphate metabolic process; GO:0031326 regulation of cellular biosynthetic process; GO:0034097 response to cytokine; GO:0030816 positive regulation of cAMP metabolic process; GO:0002446 neutrophil mediated immunity; GO:0051962 positive regulation of nervous system development; GO:0048522 positive regulation of cellular process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0042221 response to chemical; GO:0045664 regulation of neuron differentiation; GO:1900371 regulation of purine nucleotide biosynthetic process; GO:0032940 secretion by cell; GO:0045762 positive regulation of adenylate cyclase activity; GO:0007568 aging; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0043299 leukocyte degranulation; GO:0030804 positive regulation of cyclic nucleotide biosynthetic process; GO:0052547 regulation of peptidase activity; GO:0048856 anatomical structure development; GO:1905048 regulation of metallopeptidase activity; GO:2000026 regulation of multicellular organismal development; GO:0016043 cellular component organization; GO:0045786 negative regulation of cell cycle; GO:0042177 negative regulation of protein catabolic process; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:1905049 negative regulation of metallopeptidase activity; GO:0046578 regulation of Ras protein signal transduction; GO:0031324 negative regulation of cellular metabolic process; GO:1900544 positive regulation of purine nucleotide metabolic process; GO:0050896 response to stimulus; GO:0051346 negative regulation of hydrolase activity; GO:0030154 cell differentiation; GO:0043408 regulation of MAPK cascade; GO:0023056 positive regulation of signaling; GO:0009895 negative regulation of catabolic process; GO:0010647 positive regulation of cell communication; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0001932 regulation of protein phosphorylation; GO:0031401 positive regulation of protein modification process; GO:0048585 negative regulation of response to stimulus; GO:0001934 positive regulation of protein phosphorylation; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:1900542 regulation of purine nucleotide metabolic process; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0031281 positive regulation of cyclase activity; GO:0051248 negative regulation of protein metabolic process; GO:0022411 cellular component disassembly; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0009967 positive regulation of signal transduction; GO:0043410 positive regulation of MAPK cascade; GO:0009725 response to hormone; GO:0051058 negative regulation of small GTPase mediated signal transduction; GO:0050767 regulation of neurogenesis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0034774 secretory granule lumen; GO:1904724 tertiary granule lumen; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0043025 neuronal cell body; GO:0044433 cytoplasmic vesicle part; GO:0030426 growth cone; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0070820 tertiary granule; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044463 cell projection part; GO:0030427 site of polarized growth; GO:0005576 extracellular region; GO:0031012 extracellular matrix; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0060205 cytoplasmic vesicle lumen; GO:0035580 specific granule lumen; GO:0042581 specific granule; GO:0005578 proteinaceous extracellular matrix; GO:0009986 cell surface; GO:0044297 cell body; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005102 receptor binding; GO:0043167 ion binding; GO:0061134 peptidase regulator activity; GO:0044877 macromolecular complex binding; GO:0005515 protein binding; GO:0005178 integrin binding; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0004866 endopeptidase inhibitor activity; GO:0002020 protease binding; GO:0050839 cell adhesion molecule binding; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0030414 peptidase inhibitor activity; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0008191 metalloendopeptidase inhibitor activity; GO:0061135 endopeptidase regulator activity; GO:0019899 enzyme binding; GO:0032403 protein complex binding; ",{"$nulls":3},"IPR008993; IPR001134; IPR027465; ","\"Tissue inhibitor of metalloproteinases-like, OB-fold; Netrin domain; Proteinase inhibitor I35b (TIMP), C-terminal; \"\r"]
["P16050","Arachidonate 15-lipoxygenase OS=Homo sapiens OX=9606 GN=ALOX15","ALOX15",74.804,13.09,8.6,6,8,6,1.241,1.259,1.234,0.744,0.714,0.846,0.617,0.011,"cytoplasm\r","GO:0060627 regulation of vesicle-mediated transport; GO:0006646 phosphatidylethanolamine biosynthetic process; GO:1901074 regulation of engulfment of apoptotic cell; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:2001300 lipoxin metabolic process; GO:0035358 regulation of peroxisome proliferator activated receptor signaling pathway; GO:0044255 cellular lipid metabolic process; GO:0030832 regulation of actin filament length; GO:0071345 cellular response to cytokine stimulus; GO:0044237 cellular metabolic process; GO:0008610 lipid biosynthetic process; GO:0008152 metabolic process; GO:0032879 regulation of localization; GO:0032535 regulation of cellular component size; GO:2001301 lipoxin biosynthetic process; GO:0032787 monocarboxylic acid metabolic process; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0051493 regulation of cytoskeleton organization; GO:0006690 icosanoid metabolic process; GO:0044765 single-organism transport; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0051174 regulation of phosphorus metabolic process; GO:0046337 phosphatidylethanolamine metabolic process; GO:0080090 regulation of primary metabolic process; GO:0001503 ossification; GO:0044281 small molecule metabolic process; GO:2001303 lipoxin A4 biosynthetic process; GO:0044763 single-organism cellular process; GO:1901617 organic hydroxy compound biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0010811 positive regulation of cell-substrate adhesion; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0090407 organophosphate biosynthetic process; GO:0030282 bone mineralization; GO:0048513 animal organ development; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:0010604 positive regulation of macromolecule metabolic process; GO:0002682 regulation of immune system process; GO:1902905 positive regulation of supramolecular fiber organization; GO:0043436 oxoacid metabolic process; GO:1902903 regulation of supramolecular fiber organization; GO:0050794 regulation of cellular process; GO:0033559 unsaturated fatty acid metabolic process; GO:0044707 single-multicellular organism process; GO:0033554 cellular response to stress; GO:0019369 arachidonic acid metabolic process; GO:0042759 long-chain fatty acid biosynthetic process; GO:1901615 organic hydroxy compound metabolic process; GO:0034976 response to endoplasmic reticulum stress; GO:0032956 regulation of actin cytoskeleton organization; GO:0060099 regulation of phagocytosis, engulfment; GO:0031399 regulation of protein modification process; GO:0048519 negative regulation of biological process; GO:0070372 regulation of ERK1 and ERK2 cascade; GO:1902578 single-organism localization; GO:0031214 biomineral tissue development; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:1902531 regulation of intracellular signal transduction; GO:0030100 regulation of endocytosis; GO:0051495 positive regulation of cytoskeleton organization; GO:0044711 single-organism biosynthetic process; GO:0006950 response to stress; GO:0045785 positive regulation of cell adhesion; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0006691 leukotriene metabolic process; GO:1901570 fatty acid derivative biosynthetic process; GO:0032970 regulation of actin filament-based process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0030838 positive regulation of actin filament polymerization; GO:1901576 organic substance biosynthetic process; GO:0030155 regulation of cell adhesion; GO:0008064 regulation of actin polymerization or depolymerization; GO:0051247 positive regulation of protein metabolic process; GO:0006793 phosphorus metabolic process; GO:0001676 long-chain fatty acid metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0044283 small molecule biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0006644 phospholipid metabolic process; GO:0048584 positive regulation of response to stimulus; GO:0010810 regulation of cell-substrate adhesion; GO:0071248 cellular response to metal ion; GO:0051179 localization; GO:0072330 monocarboxylic acid biosynthetic process; GO:0051122 hepoxilin biosynthetic process; GO:0030833 regulation of actin filament polymerization; GO:2000425 regulation of apoptotic cell clearance; GO:0046486 glycerolipid metabolic process; GO:0032273 positive regulation of protein polymerization; GO:0016053 organic acid biosynthetic process; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0008654 phospholipid biosynthetic process; GO:0044699 single-organism process; GO:1901568 fatty acid derivative metabolic process; GO:0009058 biosynthetic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0006909 phagocytosis; GO:0009611 response to wounding; GO:0051130 positive regulation of cellular component organization; GO:0046456 icosanoid biosynthetic process; GO:0010646 regulation of cell communication; GO:0009893 positive regulation of metabolic process; GO:0002819 regulation of adaptive immune response; GO:0006650 glycerophospholipid metabolic process; GO:0032271 regulation of protein polymerization; GO:0050777 negative regulation of immune response; GO:0019372 lipoxygenase pathway; GO:0031334 positive regulation of protein complex assembly; GO:0010035 response to inorganic substance; GO:0050764 regulation of phagocytosis; GO:0070887 cellular response to chemical stimulus; GO:0006629 lipid metabolic process; GO:0032502 developmental process; GO:2001302 lipoxin A4 metabolic process; GO:0045937 positive regulation of phosphate metabolic process; GO:0009888 tissue development; GO:0034097 response to cytokine; GO:1905153 regulation of membrane invagination; GO:0055114 oxidation-reduction process; GO:0048522 positive regulation of cellular process; GO:0006636 unsaturated fatty acid biosynthetic process; GO:0006633 fatty acid biosynthetic process; GO:0010038 response to metal ion; GO:0002683 negative regulation of immune system process; GO:0002820 negative regulation of adaptive immune response; GO:0046394 carboxylic acid biosynthetic process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0043254 regulation of protein complex assembly; GO:0034114 regulation of heterotypic cell-cell adhesion; GO:0010638 positive regulation of organelle organization; GO:0006954 inflammatory response; GO:0046474 glycerophospholipid biosynthetic process; GO:0019222 regulation of metabolic process; GO:0071241 cellular response to inorganic substance; GO:0019220 regulation of phosphate metabolic process; GO:0006952 defense response; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:0035962 response to interleukin-13; GO:0016043 cellular component organization; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0044087 regulation of cellular component biogenesis; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0034116 positive regulation of heterotypic cell-cell adhesion; GO:0043408 regulation of MAPK cascade; GO:0023056 positive regulation of signaling; GO:0043277 apoptotic cell clearance; GO:0051592 response to calcium ion; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:0022409 positive regulation of cell-cell adhesion; GO:0051049 regulation of transport; GO:0001932 regulation of protein phosphorylation; GO:0031401 positive regulation of protein modification process; GO:0071277 cellular response to calcium ion; GO:0033043 regulation of organelle organization; GO:0048585 negative regulation of response to stimulus; GO:0006631 fatty acid metabolic process; GO:0001934 positive regulation of protein phosphorylation; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0035963 cellular response to interleukin-13; GO:0044249 cellular biosynthetic process; GO:0022407 regulation of cell-cell adhesion; GO:0045017 glycerolipid biosynthetic process; GO:0051121 hepoxilin metabolic process; GO:0042060 wound healing; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0019752 carboxylic acid metabolic process; GO:0090066 regulation of anatomical structure size; GO:0009967 positive regulation of signal transduction; GO:0051128 regulation of cellular component organization; GO:0043410 positive regulation of MAPK cascade; GO:0070374 positive regulation of ERK1 and ERK2 cascade; GO:0044089 positive regulation of cellular component biogenesis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0043232 intracellular non-membrane-bounded organelle; GO:0019898 extrinsic component of membrane; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0019897 extrinsic component of plasma membrane; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0031234 extrinsic component of cytoplasmic side of plasma membrane; GO:0005623 cell; GO:0009898 cytoplasmic side of plasma membrane; GO:0098562 cytoplasmic side of membrane; GO:0005886 plasma membrane; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0005811 lipid particle; GO:0044444 cytoplasmic part; GO:0098552 side of membrane; ","GO:0004052 arachidonate 12-lipoxygenase activity; GO:1901981 phosphatidylinositol phosphate binding; GO:0016801 hydrolase activity, acting on ether bonds; GO:0005506 iron ion binding; GO:0043167 ion binding; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:1902936 phosphatidylinositol bisphosphate binding; GO:0016491 oxidoreductase activity; GO:0097260 eoxin A4 synthase activity; GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; GO:0016853 isomerase activity; GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0051213 dioxygenase activity; GO:0005488 binding; GO:0005546 phosphatidylinositol-4,5-bisphosphate binding; GO:0051120 hepoxilin A3 synthase activity; GO:0035091 phosphatidylinositol binding; GO:0005543 phospholipid binding; GO:0008289 lipid binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0043168 anion binding; GO:0050473 arachidonate 15-lipoxygenase activity; GO:0047977 hepoxilin-epoxide hydrolase activity; GO:0016803 ether hydrolase activity; ","K00460","ALOX15; arachidonate 15-lipoxygenase [EC:1.13.11.33]","hsa00591 Linoleic acid metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa04726 Serotonergic synapse - Homo sapiens (human); hsa04216 Ferroptosis - Homo sapiens (human); hsa00590 Arachidonic acid metabolism - Homo sapiens (human); hsa04217 Necroptosis - Homo sapiens (human); ","IPR001024; IPR013819; ","\"PLAT/LH2 domain; Lipoxygenase, C-terminal; \"\r"]
["P16070","CD44 antigen OS=Homo sapiens OX=9606 GN=CD44","CD44",81.537,81.135,13.2,10,26,10,0.989,0.982,0.955,1.011,1.022,1.041,1.051,0.0225,"extr_plas\r","GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0045321 leukocyte activation; GO:0032270 positive regulation of cellular protein metabolic process; GO:0007166 cell surface receptor signaling pathway; GO:0070486 leukocyte aggregation; GO:0071345 cellular response to cytokine stimulus; GO:0030203 glycosaminoglycan metabolic process; GO:0022610 biological adhesion; GO:0010466 negative regulation of peptidase activity; GO:0008152 metabolic process; GO:1902165 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; GO:0007160 cell-matrix adhesion; GO:0009719 response to endogenous stimulus; GO:0007155 cell adhesion; GO:0070848 response to growth factor; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0043170 macromolecule metabolic process; GO:1902229 regulation of intrinsic apoptotic signaling pathway in response to DNA damage; GO:0061448 connective tissue development; GO:0033138 positive regulation of peptidyl-serine phosphorylation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0052548 regulation of endopeptidase activity; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0002443 leukocyte mediated immunity; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0048870 cell motility; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0006027 glycosaminoglycan catabolic process; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:2001021 negative regulation of response to DNA damage stimulus; GO:0048513 animal organ development; GO:0050900 leukocyte migration; GO:1902532 negative regulation of intracellular signal transduction; GO:0080135 regulation of cellular response to stress; GO:0051336 regulation of hydrolase activity; GO:1902253 regulation of intrinsic apoptotic signaling pathway by p53 class mediator; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0098602 single organism cell adhesion; GO:0010604 positive regulation of macromolecule metabolic process; GO:0060548 negative regulation of cell death; GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator; GO:0050794 regulation of cellular process; GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation; GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0044707 single-multicellular organism process; GO:0010951 negative regulation of endopeptidase activity; GO:0002283 neutrophil activation involved in immune response; GO:2001020 regulation of response to DNA damage stimulus; GO:0031399 regulation of protein modification process; GO:0043067 regulation of programmed cell death; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:1900623 regulation of monocyte aggregation; GO:0070372 regulation of ERK1 and ERK2 cascade; GO:0023057 negative regulation of signaling; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0010648 negative regulation of cell communication; GO:0043062 extracellular structure organization; GO:0071774 response to fibroblast growth factor; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:1901135 carbohydrate derivative metabolic process; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:1901797 negative regulation of signal transduction by p53 class mediator; GO:0045861 negative regulation of proteolysis; GO:1902531 regulation of intracellular signal transduction; GO:0006950 response to stress; GO:0045785 positive regulation of cell adhesion; GO:0033135 regulation of peptidyl-serine phosphorylation; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator; GO:1901136 carbohydrate derivative catabolic process; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0030162 regulation of proteolysis; GO:0002263 cell activation involved in immune response; GO:1903039 positive regulation of leukocyte cell-cell adhesion; GO:0009892 negative regulation of metabolic process; GO:0030155 regulation of cell adhesion; GO:0045055 regulated exocytosis; GO:0051247 positive regulation of protein metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0006928 movement of cell or subcellular component; GO:0001775 cell activation; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0006955 immune response; GO:0006887 exocytosis; GO:1901564 organonitrogen compound metabolic process; GO:0051674 localization of cell; GO:0009968 negative regulation of signal transduction; GO:0051216 cartilage development; GO:0006026 aminoglycan catabolic process; GO:1900625 positive regulation of monocyte aggregation; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0071346 cellular response to interferon-gamma; GO:0044699 single-organism process; GO:0071363 cellular response to growth factor stimulus; GO:0051234 establishment of localization; GO:0060333 interferon-gamma-mediated signaling pathway; GO:2001233 regulation of apoptotic signaling pathway; GO:0007165 signal transduction; GO:0016337 single organismal cell-cell adhesion; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:2001243 negative regulation of intrinsic apoptotic signaling pathway; GO:0009893 positive regulation of metabolic process; GO:0070487 monocyte aggregation; GO:0022617 extracellular matrix disassembly; GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator; GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; GO:0030198 extracellular matrix organization; GO:0070887 cellular response to chemical stimulus; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:0045937 positive regulation of phosphate metabolic process; GO:0009888 tissue development; GO:0034097 response to cytokine; GO:2000116 regulation of cysteine-type endopeptidase activity; GO:0002446 neutrophil mediated immunity; GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage; GO:0098609 cell-cell adhesion; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0034114 regulation of heterotypic cell-cell adhesion; GO:0032940 secretion by cell; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0040011 locomotion; GO:0043299 leukocyte degranulation; GO:0019220 regulation of phosphate metabolic process; GO:0006952 defense response; GO:0052547 regulation of peptidase activity; GO:0048856 anatomical structure development; GO:0001501 skeletal system development; GO:0016477 cell migration; GO:0016043 cellular component organization; GO:0007159 leukocyte cell-cell adhesion; GO:0043069 negative regulation of programmed cell death; GO:0002252 immune effector process; GO:0050730 regulation of peptidyl-tyrosine phosphorylation; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0051346 negative regulation of hydrolase activity; GO:0045087 innate immune response; GO:0071704 organic substance metabolic process; GO:0034116 positive regulation of heterotypic cell-cell adhesion; GO:0043408 regulation of MAPK cascade; GO:0043066 negative regulation of apoptotic process; GO:0023056 positive regulation of signaling; GO:1901796 regulation of signal transduction by p53 class mediator; GO:2000117 negative regulation of cysteine-type endopeptidase activity; GO:0010647 positive regulation of cell communication; GO:0036230 granulocyte activation; GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0006022 aminoglycan metabolic process; GO:0019221 cytokine-mediated signaling pathway; GO:0009987 cellular process; GO:0030212 hyaluronan metabolic process; GO:1903510 mucopolysaccharide metabolic process; GO:0030214 hyaluronan catabolic process; GO:0022409 positive regulation of cell-cell adhesion; GO:0001932 regulation of protein phosphorylation; GO:0006807 nitrogen compound metabolic process; GO:0031401 positive regulation of protein modification process; GO:0048585 negative regulation of response to stimulus; GO:0034341 response to interferon-gamma; GO:0043312 neutrophil degranulation; GO:0001934 positive regulation of protein phosphorylation; GO:0048518 positive regulation of biological process; GO:0022407 regulation of cell-cell adhesion; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:1901565 organonitrogen compound catabolic process; GO:0031589 cell-substrate adhesion; GO:0071495 cellular response to endogenous stimulus; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0044344 cellular response to fibroblast growth factor stimulus; GO:0009057 macromolecule catabolic process; GO:2001242 regulation of intrinsic apoptotic signaling pathway; GO:0051248 negative regulation of protein metabolic process; GO:0022411 cellular component disassembly; GO:0009967 positive regulation of signal transduction; GO:0043410 positive regulation of MAPK cascade; GO:0070374 positive regulation of ERK1 and ERK2 cascade; GO:0009056 catabolic process; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0099503 secretory vesicle; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0031226 intrinsic component of plasma membrane; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0043235 receptor complex; GO:0070161 anchoring junction; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0030667 secretory granule membrane; GO:0044459 plasma membrane part; GO:0035692 macrophage migration inhibitory factor receptor complex; GO:0009986 cell surface; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0097367 carbohydrate derivative binding; GO:0005488 binding; GO:0005540 hyaluronic acid binding; GO:0044877 macromolecular complex binding; GO:0005515 protein binding; GO:0005518 collagen binding; GO:0005539 glycosaminoglycan binding; GO:0032403 protein complex binding; ","K06256","CD44; CD44 antigen","hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa05206 MicroRNAs in cancer - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); hsa04512 ECM-receptor interaction - Homo sapiens (human); hsa04640 Hematopoietic cell lineage - Homo sapiens (human); hsa05131 Shigellosis - Homo sapiens (human); ","IPR016187; IPR000538; IPR016186; ","C-type lectin fold; Link domain; C-type lectin-like/link domain; \r"]
["P16083","Ribosyldihydronicotinamide dehydrogenase [quinone] OS=Homo sapiens OX=9606 GN=NQO2","NQO2",25.918,15.452,13,2,2,2,1.088,0.975,0.992,1.055,1.041,0.864,0.969,0.661,"cytoplasm\r","GO:0010941 regulation of cell death; GO:0032270 positive regulation of cellular protein metabolic process; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0043523 regulation of neuron apoptotic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0050877 neurological system process; GO:0007610 behavior; GO:0008152 metabolic process; GO:0010646 regulation of cell communication; GO:0009893 positive regulation of metabolic process; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0070887 cellular response to chemical stimulus; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0051174 regulation of phosphorus metabolic process; GO:0045937 positive regulation of phosphate metabolic process; GO:0080090 regulation of primary metabolic process; GO:0055114 oxidation-reduction process; GO:0048522 positive regulation of cellular process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0010942 positive regulation of cell death; GO:0043525 positive regulation of neuron apoptotic process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:0010604 positive regulation of macromolecule metabolic process; GO:0007613 memory; GO:0019222 regulation of metabolic process; GO:1904705 regulation of vascular smooth muscle cell proliferation; GO:0019220 regulation of phosphate metabolic process; GO:2000377 regulation of reactive oxygen species metabolic process; GO:0044708 single-organism behavior; GO:0043068 positive regulation of programmed cell death; GO:0050794 regulation of cellular process; GO:0071466 cellular response to xenobiotic stimulus; GO:0044707 single-multicellular organism process; GO:0042127 regulation of cell proliferation; GO:0048660 regulation of smooth muscle cell proliferation; GO:0060255 regulation of macromolecule metabolic process; GO:1904707 positive regulation of vascular smooth muscle cell proliferation; GO:0031399 regulation of protein modification process; GO:0043067 regulation of programmed cell death; GO:0043065 positive regulation of apoptotic process; GO:0050896 response to stimulus; GO:0070372 regulation of ERK1 and ERK2 cascade; GO:0009410 response to xenobiotic stimulus; GO:0006805 xenobiotic metabolic process; GO:1901216 positive regulation of neuron death; GO:0043408 regulation of MAPK cascade; GO:0023056 positive regulation of signaling; GO:0050890 cognition; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:0009966 regulation of signal transduction; GO:1901214 regulation of neuron death; GO:1902531 regulation of intracellular signal transduction; GO:0003008 system process; GO:0001932 regulation of protein phosphorylation; GO:0031401 positive regulation of protein modification process; GO:0001934 positive regulation of protein phosphorylation; GO:0048518 positive regulation of biological process; GO:0007611 learning or memory; GO:2000379 positive regulation of reactive oxygen species metabolic process; GO:0051247 positive regulation of protein metabolic process; GO:0051246 regulation of protein metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0009967 positive regulation of signal transduction; GO:0048661 positive regulation of smooth muscle cell proliferation; GO:0043410 positive regulation of MAPK cascade; GO:0048584 positive regulation of response to stimulus; GO:0070374 positive regulation of ERK1 and ERK2 cascade; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; GO:0008284 positive regulation of cell proliferation; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0001512 dihydronicotinamide riboside quinone reductase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0016491 oxidoreductase activity; ","K08071",null,null,"IPR003680; IPR029039; ","Flavodoxin-like fold; Flavoprotein-like domain; \r"]
["P16104","Histone H2AX OS=Homo sapiens OX=9606 GN=H2AFX","H2AFX",15.144,11.957,28,6,19,3,1.116,1.058,1.204,0.761,1.049,0.828,0.781,0.0686,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0022414 reproductive process; GO:0007420 brain development; GO:0021987 cerebral cortex development; GO:0044237 cellular metabolic process; GO:0021537 telencephalon development; GO:0008152 metabolic process; GO:0006334 nucleosome assembly; GO:0065003 macromolecular complex assembly; GO:0044702 single organism reproductive process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0071214 cellular response to abiotic stimulus; GO:0080090 regulation of primary metabolic process; GO:0051054 positive regulation of DNA metabolic process; GO:0019953 sexual reproduction; GO:0044763 single-organism cellular process; GO:0090398 cellular senescence; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0065004 protein-DNA complex assembly; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0007569 cell aging; GO:0080135 regulation of cellular response to stress; GO:0071480 cellular response to gamma radiation; GO:0007417 central nervous system development; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0048609 multicellular organismal reproductive process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0000003 reproduction; GO:0050794 regulation of cellular process; GO:0034728 nucleosome organization; GO:0033554 cellular response to stress; GO:0044707 single-multicellular organism process; GO:2001020 regulation of response to DNA damage stimulus; GO:0009628 response to abiotic stimulus; GO:0006259 DNA metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:0045892 negative regulation of transcription, DNA-templated; GO:0006323 DNA packaging; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0030900 forebrain development; GO:0007275 multicellular organism development; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0006950 response to stress; GO:0007283 spermatogenesis; GO:0048731 system development; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0006974 cellular response to DNA damage stimulus; GO:0000725 recombinational repair; GO:0009890 negative regulation of biosynthetic process; GO:0051276 chromosome organization; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0048584 positive regulation of response to stimulus; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0051253 negative regulation of RNA metabolic process; GO:0006282 regulation of DNA repair; GO:2001141 regulation of RNA biosynthetic process; GO:0000077 DNA damage checkpoint; GO:0009893 positive regulation of metabolic process; GO:0022607 cellular component assembly; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0000075 cell cycle checkpoint; GO:0009314 response to radiation; GO:0060322 head development; GO:0071479 cellular response to ionizing radiation; GO:0051726 regulation of cell cycle; GO:0031497 chromatin assembly; GO:2001022 positive regulation of response to DNA damage stimulus; GO:0006310 DNA recombination; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0071103 DNA conformation change; GO:0071824 protein-DNA complex subunit organization; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0006333 chromatin assembly or disassembly; GO:0031326 regulation of cellular biosynthetic process; GO:0031570 DNA integrity checkpoint; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0051321 meiotic cell cycle; GO:0010605 negative regulation of macromolecule metabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0051052 regulation of DNA metabolic process; GO:0007568 aging; GO:1902679 negative regulation of RNA biosynthetic process; GO:0019222 regulation of metabolic process; GO:0006325 chromatin organization; GO:0045814 negative regulation of gene expression, epigenetic; GO:0048856 anatomical structure development; GO:0006303 double-strand break repair via nonhomologous end joining; GO:0021543 pallium development; GO:0016043 cellular component organization; GO:0045786 negative regulation of cell cycle; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0010332 response to gamma radiation; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0006302 double-strand break repair; GO:0031324 negative regulation of cellular metabolic process; GO:0045739 positive regulation of DNA repair; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0006342 chromatin silencing; GO:0016032 viral process; GO:0034641 cellular nitrogen compound metabolic process; GO:0071478 cellular response to radiation; GO:0009987 cellular process; GO:0000724 double-strand break repair via homologous recombination; GO:0034622 cellular macromolecular complex assembly; GO:0006355 regulation of transcription, DNA-templated; GO:0048232 male gamete generation; GO:0010629 negative regulation of gene expression; GO:0000726 non-recombinational repair; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0007276 gamete generation; GO:0043933 macromolecular complex subunit organization; GO:0032504 multicellular organism reproduction; GO:0040029 regulation of gene expression, epigenetic; GO:0010212 response to ionizing radiation; GO:0006281 DNA repair; GO:0016458 gene silencing; GO:0044767 single-organism developmental process; GO:0044703 multi-organism reproductive process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0007049 cell cycle; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0000803 sex chromosome; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0000793 condensed chromosome; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044454 nuclear chromosome part; GO:0016607 nuclear speck; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0000790 nuclear chromatin; GO:1903561 extracellular vesicle; GO:0001673 male germ cell nucleus; GO:0043227 membrane-bounded organelle; GO:0044815 DNA packaging complex; GO:0032993 protein-DNA complex; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0005657 replication fork; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0001741 XY body; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005576 extracellular region; GO:0090734 site of DNA damage; GO:0000786 nucleosome; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0000785 chromatin; GO:0035861 site of double-strand break; GO:0000228 nuclear chromosome; GO:0043073 germ cell nucleus; GO:0000794 condensed nuclear chromosome; GO:0043230 extracellular organelle; GO:0044428 nuclear part; ","GO:0042393 histone binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003677 DNA binding; GO:0046982 protein heterodimerization activity; GO:0005488 binding; GO:0046983 protein dimerization activity; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0003684 damaged DNA binding; GO:0019899 enzyme binding; ","K11251","H2A; histone H2A","hsa05322 Systemic lupus erythematosus - Homo sapiens (human); hsa05034 Alcoholism - Homo sapiens (human); hsa04217 Necroptosis - Homo sapiens (human); ","IPR032454; IPR009072; IPR007125; ","\"Histone H2A, C-terminal domain; Histone-fold; Histone H2A/H2B/H3; \"\r"]
["P16144","Integrin beta-4 OS=Homo sapiens OX=9606 GN=ITGB4","ITGB4",202.16,122.31,18.7,28,34,28,1.08,1.019,1.06,0.966,0.931,0.949,0.901,0.00668,"extr_plas\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0051674 localization of cell; GO:0007166 cell surface receptor signaling pathway; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0006914 autophagy; GO:0044237 cellular metabolic process; GO:0009611 response to wounding; GO:0022610 biological adhesion; GO:0048729 tissue morphogenesis; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0042475 odontogenesis of dentin-containing tooth; GO:0007160 cell-matrix adhesion; GO:0007155 cell adhesion; GO:0060173 limb development; GO:0030198 extracellular matrix organization; GO:0009790 embryo development; GO:0048598 embryonic morphogenesis; GO:0032502 developmental process; GO:0007044 cell-substrate junction assembly; GO:0035295 tube development; GO:0051716 cellular response to stimulus; GO:0043588 skin development; GO:0009888 tissue development; GO:0001704 formation of primary germ layer; GO:0001707 mesoderm formation; GO:0044763 single-organism cellular process; GO:0048870 cell motility; GO:0007229 integrin-mediated signaling pathway; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0042476 odontogenesis; GO:0007498 mesoderm development; GO:0001655 urogenital system development; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0031581 hemidesmosome assembly; GO:0009887 animal organ morphogenesis; GO:0040011 locomotion; GO:0048856 anatomical structure development; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0034329 cell junction assembly; GO:0016043 cellular component organization; GO:0072001 renal system development; GO:0035878 nail development; GO:0050896 response to stimulus; GO:0007369 gastrulation; GO:0009653 anatomical structure morphogenesis; GO:0030154 cell differentiation; GO:0043062 extracellular structure organization; GO:0044248 cellular catabolic process; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0006950 response to stress; GO:0048731 system development; GO:0055123 digestive system development; GO:0048333 mesodermal cell differentiation; GO:0048736 appendage development; GO:0048332 mesoderm morphogenesis; GO:0034330 cell junction organization; GO:0031589 cell-substrate adhesion; GO:0044767 single-organism developmental process; GO:0048565 digestive tract development; GO:0097186 amelogenesis; GO:0006928 movement of cell or subcellular component; GO:0051179 localization; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0098636 protein complex involved in cell adhesion; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0030054 cell junction; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044425 membrane part; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0030055 cell-substrate junction; GO:0030056 hemidesmosome; GO:0043227 membrane-bounded organelle; GO:0031252 cell leading edge; GO:0043229 intracellular organelle; GO:0031226 intrinsic component of plasma membrane; GO:0098802 plasma membrane receptor complex; GO:0098797 plasma membrane protein complex; GO:0043235 receptor complex; GO:0008305 integrin complex; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0009986 cell surface; GO:0043234 protein complex; GO:0043230 extracellular organelle; ","GO:0001664 G-protein coupled receptor binding; GO:0060089 molecular transducer activity; GO:0005515 protein binding; GO:0004872 receptor activity; GO:0005102 receptor binding; GO:0005488 binding; ","K06525","ITGB4; integrin beta 4","hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa05414 Dilated cardiomyopathy (DCM) - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa04512 ECM-receptor interaction - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa05410 Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human); ","IPR033760; IPR002369; IPR016201; IPR012896; IPR003961; IPR013111; IPR013783; IPR003644; IPR002035; ","\"Integrin beta N-terminal; Integrin beta subunit, VWA domain; PSI domain; Integrin beta subunit, tail; Fibronectin type III; EGF-like domain, extracellular; Immunoglobulin-like fold; Na-Ca exchanger/integrin-beta4; von Willebrand factor, type A; \"\r"]
["P16152","Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1","CBR1",30.375,204.46,74.4,15,40,13,1.016,1.008,1.022,0.97,0.982,0.993,0.967,0.0127,"cytoplasm\r","GO:0019371 cyclooxygenase pathway; GO:0033559 unsaturated fatty acid metabolic process; GO:0019369 arachidonic acid metabolic process; GO:0016053 organic acid biosynthetic process; GO:0048869 cellular developmental process; GO:1901568 fatty acid derivative metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0001516 prostaglandin biosynthetic process; GO:0071704 organic substance metabolic process; GO:0008610 lipid biosynthetic process; GO:0006775 fat-soluble vitamin metabolic process; GO:0030154 cell differentiation; GO:0006766 vitamin metabolic process; GO:0046456 icosanoid biosynthetic process; GO:0008152 metabolic process; GO:0042180 cellular ketone metabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0009987 cellular process; GO:0006690 icosanoid metabolic process; GO:0006629 lipid metabolic process; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0009888 tissue development; GO:0044711 single-organism biosynthetic process; GO:0017144 drug metabolic process; GO:0055114 oxidation-reduction process; GO:0046457 prostanoid biosynthetic process; GO:1901661 quinone metabolic process; GO:0044281 small molecule metabolic process; GO:0006692 prostanoid metabolic process; GO:0042373 vitamin K metabolic process; GO:1901570 fatty acid derivative biosynthetic process; GO:0044763 single-organism cellular process; GO:0006636 unsaturated fatty acid biosynthetic process; GO:0006631 fatty acid metabolic process; GO:0044238 primary metabolic process; GO:0006633 fatty acid biosynthetic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0051186 cofactor metabolic process; GO:0046394 carboxylic acid biosynthetic process; GO:0044767 single-organism developmental process; GO:0001676 long-chain fatty acid metabolic process; GO:0044710 single-organism metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0044283 small molecule biosynthetic process; GO:0006693 prostaglandin metabolic process; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:0072330 monocarboxylic acid biosynthetic process; GO:0043436 oxoacid metabolic process; GO:0030855 epithelial cell differentiation; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016614 oxidoreductase activity, acting on CH-OH group of donors; GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; GO:0003824 catalytic activity; GO:0004090 carbonyl reductase (NADPH) activity; GO:0050221 prostaglandin-E2 9-reductase activity; GO:0047021 15-hydroxyprostaglandin dehydrogenase (NADP+) activity; GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; GO:0016491 oxidoreductase activity; ","K00079","CBR1; carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197]","hsa00790 Folate biosynthesis - Homo sapiens (human); hsa05204 Chemical carcinogenesis - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00980 Metabolism of xenobiotics by cytochrome P450 - Homo sapiens (human); hsa00590 Arachidonic acid metabolism - Homo sapiens (human); ","IPR016040; ","NAD(P)-binding domain; \r"]
["P16157","Ankyrin-1 OS=Homo sapiens OX=9606 GN=ANK1","ANK1",206.26,231.55,25.7,41,65,39,0.859,0.867,0.858,1.122,1.15,1.138,1.32,1.93e-06,"nucleus\r","GO:0044700 single organism signaling; GO:0010256 endomembrane system organization; GO:0035088 establishment or maintenance of apical/basal cell polarity; GO:0044699 single-organism process; GO:0090002 establishment of protein localization to plasma membrane; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0046903 secretion; GO:0030011 maintenance of cell polarity; GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity; GO:0044765 single-organism transport; GO:0051716 cellular response to stimulus; GO:0072657 protein localization to membrane; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0007163 establishment or maintenance of cell polarity; GO:0007009 plasma membrane organization; GO:0023052 signaling; GO:1902582 single-organism intracellular transport; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0010638 positive regulation of organelle organization; GO:0032940 secretion by cell; GO:0035090 maintenance of apical/basal cell polarity; GO:0045199 maintenance of epithelial cell apical/basal polarity; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0072661 protein targeting to plasma membrane; GO:0048193 Golgi vesicle transport; GO:0050896 response to stimulus; GO:1990778 protein localization to cell periphery; GO:1902578 single-organism localization; GO:0006886 intracellular protein transport; GO:1902580 single-organism cellular localization; GO:0034613 cellular protein localization; GO:0007010 cytoskeleton organization; GO:0061245 establishment or maintenance of bipolar cell polarity; GO:0009987 cellular process; GO:0090150 establishment of protein localization to membrane; GO:0016192 vesicle-mediated transport; GO:0044802 single-organism membrane organization; GO:0033043 regulation of organelle organization; GO:0071702 organic substance transport; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0072659 protein localization to plasma membrane; GO:0070727 cellular macromolecule localization; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0006887 exocytosis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016323 basolateral plasma membrane; GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0071944 cell periphery; GO:0030016 myofibril; GO:0005737 cytoplasm; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0030018 Z disc; GO:0099080 supramolecular complex; GO:0016528 sarcoplasm; GO:0005623 cell; GO:0031674 I band; GO:0044422 organelle part; GO:0032589 neuron projection membrane; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0098590 plasma membrane region; GO:0031256 leading edge membrane; GO:0044304 main axon; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0030673 axolemma; GO:0043292 contractile fiber; GO:0043005 neuron projection; GO:0097060 synaptic membrane; GO:0031430 M band; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0044456 synapse part; GO:0031252 cell leading edge; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0016529 sarcoplasmic reticulum; GO:0012505 endomembrane system; GO:0044463 cell projection part; GO:0005829 cytosol; GO:0033267 axon part; GO:0045202 synapse; GO:0005886 plasma membrane; GO:0099081 supramolecular polymer; GO:0045211 postsynaptic membrane; GO:0030424 axon; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0098794 postsynapse; GO:0044459 plasma membrane part; GO:0031672 A band; GO:0030017 sarcomere; GO:0031253 cell projection membrane; GO:0044449 contractile fiber part; GO:0014731 spectrin-associated cytoskeleton; GO:0042383 sarcolemma; GO:0044444 cytoplasmic part; ","GO:0030674 protein binding, bridging; GO:0008092 cytoskeletal protein binding; GO:0005200 structural constituent of cytoskeleton; GO:0051117 ATPase binding; GO:0008093 cytoskeletal adaptor activity; GO:0005488 binding; GO:0060090 binding, bridging; GO:0005515 protein binding; GO:0005198 structural molecule activity; GO:0019899 enzyme binding; GO:0030507 spectrin binding; ","K10380","ANK; ankyrin","hsa05205 Proteoglycans in cancer - Homo sapiens (human); ","IPR000906; IPR000488; IPR020683; IPR011029; ","ZU5 domain; Death domain; Ankyrin repeat-containing domain; Death-like domain; \r"]
["P16219","Short-chain specific acyl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ACADS","ACADS",44.297,20.387,12.4,5,16,5,0.404,0.592,1.384,1.377,1.052,1.118,1.49,0.229,"mitochondria\r","GO:0034440 lipid oxidation; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0030258 lipid modification; GO:0044248 cellular catabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0009987 cellular process; GO:0006629 lipid metabolic process; GO:0016042 lipid catabolic process; GO:0019395 fatty acid oxidation; GO:0055114 oxidation-reduction process; GO:0044712 single-organism catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006635 fatty acid beta-oxidation; GO:0072329 monocarboxylic acid catabolic process; GO:0044282 small molecule catabolic process; GO:0006631 fatty acid metabolic process; GO:0044238 primary metabolic process; GO:0046395 carboxylic acid catabolic process; GO:1901575 organic substance catabolic process; GO:0044710 single-organism metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0016054 organic acid catabolic process; GO:0044242 cellular lipid catabolic process; GO:0006082 organic acid metabolic process; GO:0009062 fatty acid catabolic process; GO:0009056 catabolic process; GO:0043436 oxoacid metabolic process; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0050660 flavin adenine dinucleotide binding; GO:0043167 ion binding; GO:0000166 nucleotide binding; GO:0048037 cofactor binding; GO:0016491 oxidoreductase activity; GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043168 anion binding; GO:0004085 butyryl-CoA dehydrogenase activity; GO:0003995 acyl-CoA dehydrogenase activity; GO:0050662 coenzyme binding; GO:0036094 small molecule binding; ","K00248","ACADS; butyryl-CoA dehydrogenase [EC:1.3.8.1]","hsa00280 Valine, leucine and isoleucine degradation - Homo sapiens (human); hsa00071 Fatty acid degradation - Homo sapiens (human); hsa00650 Butanoate metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa01212 Fatty acid metabolism - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); ","IPR013786; IPR009100; IPR006091; IPR009075; ","\"Acyl-CoA dehydrogenase/oxidase, N-terminal; Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain; Acyl-CoA oxidase/dehydrogenase, central domain; Acyl-CoA dehydrogenase/oxidase C-terminal; \"\r"]
["P16284","Platelet endothelial cell adhesion molecule OS=Homo sapiens OX=9606 GN=PECAM1","PECAM1",82.521,17.871,7.9,6,8,6,1.025,1.094,1.007,0.974,0.953,0.964,0.925,0.0405,"peroxisome\r","GO:0044700 single organism signaling; GO:0045321 leukocyte activation; GO:0051674 localization of cell; GO:0001568 blood vessel development; GO:0044699 single-organism process; GO:0072011 glomerular endothelium development; GO:0006909 phagocytosis; GO:0051234 establishment of localization; GO:0050904 diapedesis; GO:0022610 biological adhesion; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0007155 cell adhesion; GO:0030198 extracellular matrix organization; GO:0002274 myeloid leukocyte activation; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0060429 epithelium development; GO:0002443 leukocyte mediated immunity; GO:0009888 tissue development; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0001944 vasculature development; GO:0048870 cell motility; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0002444 myeloid leukocyte mediated immunity; GO:0006810 transport; GO:0048513 animal organ development; GO:0001655 urogenital system development; GO:0050789 regulation of biological process; GO:0050900 leukocyte migration; GO:0032940 secretion by cell; GO:0072010 glomerular epithelium development; GO:0040011 locomotion; GO:0043299 leukocyte degranulation; GO:0048856 anatomical structure development; GO:0050794 regulation of cellular process; GO:0072359 circulatory system development; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0016477 cell migration; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0002576 platelet degranulation; GO:0061440 kidney vasculature development; GO:0072001 renal system development; GO:0050896 response to stimulus; GO:0008037 cell recognition; GO:0032835 glomerulus development; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0043062 extracellular structure organization; GO:0072006 nephron development; GO:0036230 granulocyte activation; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0072009 nephron epithelium development; GO:0001822 kidney development; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0072358 cardiovascular system development; GO:0043312 neutrophil degranulation; GO:0006897 endocytosis; GO:0002263 cell activation involved in immune response; GO:0003158 endothelium development; GO:0002366 leukocyte activation involved in immune response; GO:0072012 glomerulus vasculature development; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0044767 single-organism developmental process; GO:0045123 cellular extravasation; GO:0006928 movement of cell or subcellular component; GO:0001775 cell activation; GO:0072073 kidney epithelium development; GO:0051179 localization; GO:0006955 immune response; GO:0061437 renal system vasculature development; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:0006887 exocytosis; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0098857 membrane microdomain; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044425 membrane part; GO:0044464 cell part; GO:0098805 whole membrane; GO:0099503 secretory vesicle; GO:0098589 membrane region; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0045121 membrane raft; GO:0043227 membrane-bounded organelle; GO:0031092 platelet alpha granule membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0030667 secretory granule membrane; GO:0031091 platelet alpha granule; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ","K06471","PECAM1; platelet/endothelial cell adhesion molecule","hsa05144 Malaria - Homo sapiens (human); hsa04670 Leukocyte transendothelial migration - Homo sapiens (human); hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human); hsa04514 Cell adhesion molecules (CAMs) - Homo sapiens (human); ","IPR003598; IPR007110; IPR013783; IPR003599; ","Immunoglobulin subtype 2; Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin subtype; \r"]
["P16333","Cytoplasmic protein NCK1 OS=Homo sapiens OX=9606 GN=NCK1","NCK1",42.864,28.601,18.8,7,10,6,0.994,0.968,1.015,1.034,0.97,1.017,1.015,0.572,"nucleus\r",{"$cut":{"chars":17131,"head":"GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0002694 regulation of leukocyte activation; GO:0010941 regulation of cell death; GO:0010608 posttranscriptional regulation of gene expression; GO:0009891 positive regulation of biosynthetic process; GO:1905897 regulation of response to endoplasmic reticulum stress; GO:0044237 cellular metabolic process; GO:0009607 response to biotic stimulus; GO:0042110 T cell activation; GO:0008152 metabolic process; GO:0032946 positive regulation of mononuclear cell proliferation; GO:0065003 macromolecular complex assembly; GO:0032535 regulation of cellular component size; GO:0051493 regulation of cytoskeleton organization; GO:0006930 substrate-dependent cell migration, cell extension; GO:1905898 positive regulation of response to endoplasmic reticulum stress; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:1900102 negative regulation of endoplasmic reticulum unfolded protein response; GO:0048870 cell motility; GO:0043086 negative regulation of catalytic activity; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0080135 regulation of cellular response to stress; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:1902905 positive regulation of supramolecular fiber organization; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0048010 vascular endothelial growth factor receptor signaling pathway; GO:0060548 negative regulation of cell death; GO:0010975 regulation of neuron projection development; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0044707 single-multicellular organism process; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0048519 negative regulation of biological process; GO:0045892 negative regulation of transcription, DNA-templated; GO:1900101 regulation of endoplasmic reticulum unfolded protein response; GO:0050867 positive regulation of cell activation; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:2000145 regulation of cell motility; GO:0009889 regulation of biosynthetic process; GO:0043620 regulation of DNA-templated transcription in response to stress; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:1902680 positive regulation of RNA biosynthetic process; GO:0038093 Fc receptor signaling pathway; GO:0050778 positive regulation of immune response; GO:0006950 response to stress; GO:0045785 positive regulation of cell adhesion; GO:0051270 regulation of cellular component movement; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0032970 regulation of actin filament-based process; GO:0002376 immune system process; GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress; GO:1903039 positive regulation of leukocyte cell-cell adhesion; GO:0034248 regulation of cellular amide metabolic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0002696 positive regulation of leukocyte activation; GO:0009890 negative regulation of biosynthetic process; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:1904688 regulation of cytoplasmic translational initiation; GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis; GO:0043412 macromolecule modification; GO:0045936 negative regulation of phosphate metabolic process; GO:0008284 positive regulation of cell proliferation; GO:0097581 lamellipodium organization; GO:0009968 negative regulation of signal transduction; GO:0051674 localization of cell; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:0044699 si"}},"GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0008287 protein serine/threonine phosphatase complex; GO:0044424 intracellular part; GO:0005911 cell-cell junction; GO:0005623 cell; GO:1903293 phosphatase complex; GO:0000164 protein phosphatase type 1 complex; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:1902494 catalytic complex; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005840 ribosome; GO:0043232 intracellular non-membrane-bounded organelle; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0005829 cytosol; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0044444 cytoplasmic part; ","GO:0030674 protein binding, bridging; GO:1990782 protein tyrosine kinase binding; GO:0005102 receptor binding; GO:0019901 protein kinase binding; GO:0071074 eukaryotic initiation factor eIF2 binding; GO:0005515 protein binding; GO:0046875 ephrin receptor binding; GO:0004860 protein kinase inhibitor activity; GO:0019887 protein kinase regulator activity; GO:0019207 kinase regulator activity; GO:0019900 kinase binding; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0032947 protein complex scaffold; GO:0005070 SH3/SH2 adaptor activity; GO:0050839 cell adhesion molecule binding; GO:0008092 cytoskeletal protein binding; GO:0030971 receptor tyrosine kinase binding; GO:0035591 signaling adaptor activity; GO:0030234 enzyme regulator activity; GO:0019210 kinase inhibitor activity; GO:0008093 cytoskeletal adaptor activity; GO:0005488 binding; GO:0031369 translation initiation factor binding; GO:0045296 cadherin binding; GO:0030159 receptor signaling complex scaffold activity; GO:0019904 protein domain specific binding; GO:0060090 binding, bridging; GO:0005198 structural molecule activity; GO:0019899 enzyme binding; ","K07365","NCK1; NCK adaptor protein 1","hsa04012 ErbB signaling pathway - Homo sapiens (human); hsa04660 T cell receptor signaling pathway - Homo sapiens (human); hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human); hsa04360 Axon guidance - Homo sapiens (human); ","IPR000980; IPR001452; ","SH2 domain; SH3 domain; \r"]
["P16401","Histone H1.5 OS=Homo sapiens OX=9606 GN=HIST1H1B","HIST1H1B",22.58,28.202,29.6,9,12,6,0.91,0.943,0.951,1.042,1.058,1.095,1.139,2.82E-3,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0072594 establishment of protein localization to organelle; GO:0051253 negative regulation of RNA metabolic process; GO:0051234 establishment of localization; GO:0045927 positive regulation of growth; GO:1905269 positive regulation of chromatin organization; GO:0051130 positive regulation of cellular component organization; GO:0001558 regulation of cell growth; GO:2001141 regulation of RNA biosynthetic process; GO:0006334 nucleosome assembly; GO:0009893 positive regulation of metabolic process; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0033365 protein localization to organelle; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0031497 chromatin assembly; GO:0071824 protein-DNA complex subunit organization; GO:0071103 DNA conformation change; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0006333 chromatin assembly or disassembly; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0030307 positive regulation of cell growth; GO:0080090 regulation of primary metabolic process; GO:0070199 establishment of protein localization to chromosome; GO:0000122 negative regulation of transcription from RNA polymerase II promoter; GO:0048522 positive regulation of cellular process; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0071169 establishment of protein localization to chromatin; GO:0065004 protein-DNA complex assembly; GO:1903506 regulation of nucleic acid-templated transcription; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0010638 positive regulation of organelle organization; GO:0051574 positive regulation of histone H3-K9 methylation; GO:1902679 negative regulation of RNA biosynthetic process; GO:2001252 positive regulation of chromosome organization; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0031060 regulation of histone methylation; GO:0006325 chromatin organization; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0031056 regulation of histone modification; GO:0050794 regulation of cellular process; GO:0034502 protein localization to chromosome; GO:0031062 positive regulation of histone methylation; GO:0034728 nucleosome organization; GO:0016043 cellular component organization; GO:0040008 regulation of growth; GO:0060255 regulation of macromolecule metabolic process; GO:0031399 regulation of protein modification process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0051570 regulation of histone H3-K9 methylation; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0045892 negative regulation of transcription, DNA-templated; GO:0006323 DNA packaging; GO:0031058 positive regulation of histone modification; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0034622 cellular macromolecular complex assembly; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:1902275 regulation of chromatin organization; GO:0031401 positive regulation of protein modification process; GO:0033043 regulation of organelle organization; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0009892 negative regulation of metabolic process; GO:0033044 regulation of chromosome organization; GO:0051641 cellular localization; GO:0043933 macromolecular complex subunit organization; GO:0045184 establishment of protein localization; GO:0009890 negative regulation of biosynthetic process; GO:0071168 protein localization to chromatin; GO:0070727 cellular macromolecule localization; GO:0051247 positive regulation of protein metabolic process; GO:0051276 chromosome organization; GO:0051246 regulation of protein metabolic process; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0031647 regulation of protein stability; GO:0051128 regulation of cellular component organization; GO:0031327 negative regulation of cellular biosynthetic process; GO:0051179 localization; GO:0050821 protein stabilization; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0000792 heterochromatin; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044454 nuclear chromosome part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005694 chromosome; GO:1903561 extracellular vesicle; GO:0000790 nuclear chromatin; GO:0043227 membrane-bounded organelle; GO:0044815 DNA packaging complex; GO:0032993 protein-DNA complex; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005576 extracellular region; GO:0000786 nucleosome; GO:0005720 nuclear heterochromatin; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0000785 chromatin; GO:0000228 nuclear chromosome; GO:0043230 extracellular organelle; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003677 DNA binding; GO:0003723 RNA binding; GO:0042826 histone deacetylase binding; GO:0031490 chromatin DNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0003682 chromatin binding; GO:0019899 enzyme binding; ","K11275",null,null,"IPR011991; IPR005818; ","\"Winged helix-turn-helix DNA-binding domain; Linker histone H1/H5, domain H15; \"\r"]
["P16422","Epithelial cell adhesion molecule OS=Homo sapiens OX=9606 GN=EPCAM","EPCAM",34.932,1.9114,3.8,1,1,1,1.337,1.176,1.145,0.812,0.652,0.918,0.651,0.017,"extracellular\r","GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0051674 localization of cell; GO:0040017 positive regulation of locomotion; GO:0048869 cellular developmental process; GO:0009891 positive regulation of biosynthetic process; GO:2000648 positive regulation of stem cell proliferation; GO:0044699 single-organism process; GO:0001823 mesonephros development; GO:2001141 regulation of RNA biosynthetic process; GO:0022610 biological adhesion; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0032879 regulation of localization; GO:2000047 regulation of cell-cell adhesion mediated by cadherin; GO:0007155 cell adhesion; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0032502 developmental process; GO:0035295 tube development; GO:0060429 epithelium development; GO:0010468 regulation of gene expression; GO:0051716 cellular response to stimulus; GO:0009888 tissue development; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0098609 cell-cell adhesion; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0048870 cell motility; GO:0051272 positive regulation of cellular component movement; GO:0031323 regulation of cellular metabolic process; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0001655 urogenital system development; GO:0050789 regulation of biological process; GO:0050900 leukocyte migration; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0040011 locomotion; GO:0072163 mesonephric epithelium development; GO:0048856 anatomical structure development; GO:0060548 negative regulation of cell death; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0016477 cell migration; GO:0007162 negative regulation of cell adhesion; GO:0072091 regulation of stem cell proliferation; GO:0043069 negative regulation of programmed cell death; GO:0042127 regulation of cell proliferation; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0043067 regulation of programmed cell death; GO:0022408 negative regulation of cell-cell adhesion; GO:0072001 renal system development; GO:2000147 positive regulation of cell motility; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0030154 cell differentiation; GO:0043066 negative regulation of apoptotic process; GO:2000145 regulation of cell motility; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0007275 multicellular organism development; GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin; GO:0009987 cellular process; GO:0001822 kidney development; GO:0051254 positive regulation of RNA metabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0072164 mesonephric tubule development; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0023019 signal transduction involved in regulation of gene expression; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0002376 immune system process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0030155 regulation of cell adhesion; GO:0022407 regulation of cell-cell adhesion; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0044767 single-organism developmental process; GO:0031325 positive regulation of cellular metabolic process; GO:0048863 stem cell differentiation; GO:0006928 movement of cell or subcellular component; GO:0072073 kidney epithelium development; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules; GO:0031328 positive regulation of cellular biosynthetic process; GO:0040012 regulation of locomotion; GO:0051179 localization; GO:0001657 ureteric bud development; GO:0042981 regulation of apoptotic process; GO:0008284 positive regulation of cell proliferation; GO:0065007 biological regulation; ","GO:0016323 basolateral plasma membrane; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031226 intrinsic component of plasma membrane; GO:0016324 apical plasma membrane; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0005887 integral component of plasma membrane; GO:0005911 cell-cell junction; GO:0005623 cell; GO:0005576 extracellular region; GO:0005923 bicellular tight junction; GO:0016021 integral component of membrane; GO:0016328 lateral plasma membrane; GO:0043296 apical junction complex; GO:0005886 plasma membrane; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0070160 occluding junction; GO:0044459 plasma membrane part; GO:0098590 plasma membrane region; GO:0044464 cell part; GO:0044425 membrane part; GO:1903561 extracellular vesicle; GO:0009986 cell surface; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0045177 apical part of cell; ","GO:0098641 cadherin binding involved in cell-cell adhesion; GO:0050839 cell adhesion molecule binding; GO:0098631 protein binding involved in cell adhesion; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0045296 cadherin binding; GO:0005515 protein binding; GO:0098632 protein binding involved in cell-cell adhesion; GO:0032403 protein complex binding; ","K06737",null,null,"IPR000716; ","Thyroglobulin type-1; \r"]
["P16435","NADPH--cytochrome P450 reductase OS=Homo sapiens OX=9606 GN=POR","POR",76.689,38.227,19.6,11,15,11,0.955,0.921,0.927,1.071,1.069,1.086,1.151,0.000323,"cytoplasm\r","GO:0065008 regulation of biological quality; GO:0010941 regulation of cell death; GO:0009891 positive regulation of biosynthetic process; GO:0044255 cellular lipid metabolic process; GO:0019216 regulation of lipid metabolic process; GO:0044237 cellular metabolic process; GO:0009605 response to external stimulus; GO:0010466 negative regulation of peptidase activity; GO:1903010 regulation of bone development; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0030258 lipid modification; GO:0044093 positive regulation of molecular function; GO:0032787 monocarboxylic acid metabolic process; GO:0009719 response to endogenous stimulus; GO:0090181 regulation of cholesterol metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0046210 nitric oxide catabolic process; GO:1901652 response to peptide; GO:0046889 positive regulation of lipid biosynthetic process; GO:0090205 positive regulation of cholesterol metabolic process; GO:0052548 regulation of endopeptidase activity; GO:0051716 cellular response to stimulus; GO:0090345 cellular organohalogen metabolic process; GO:0080090 regulation of primary metabolic process; GO:0043602 nitrate catabolic process; GO:0044281 small molecule metabolic process; GO:0060191 regulation of lipase activity; GO:0044763 single-organism cellular process; GO:0051353 positive regulation of oxidoreductase activity; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0051341 regulation of oxidoreductase activity; GO:0010243 response to organonitrogen compound; GO:0051336 regulation of hydrolase activity; GO:0044710 single-organism metabolic process; GO:0032768 regulation of monooxygenase activity; GO:0006473 protein acetylation; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0046890 regulation of lipid biosynthetic process; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0044260 cellular macromolecule metabolic process; GO:0010817 regulation of hormone levels; GO:0006464 cellular protein modification process; GO:0009812 flavonoid metabolic process; GO:0051094 positive regulation of developmental process; GO:0060548 negative regulation of cell death; GO:0043436 oxoacid metabolic process; GO:0050794 regulation of cellular process; GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0008589 regulation of smoothened signaling pathway; GO:0010951 negative regulation of endopeptidase activity; GO:0042127 regulation of cell proliferation; GO:1901700 response to oxygen-containing compound; GO:0043067 regulation of programmed cell death; GO:0044267 cellular protein metabolic process; GO:0097164 ammonium ion metabolic process; GO:0019218 regulation of steroid metabolic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:1902930 regulation of alcohol biosynthetic process; GO:0045940 positive regulation of steroid metabolic process; GO:0051239 regulation of multicellular organismal process; GO:0045597 positive regulation of cell differentiation; GO:0044270 cellular nitrogen compound catabolic process; GO:0042493 response to drug; GO:0009410 response to xenobiotic stimulus; GO:0009889 regulation of biosynthetic process; GO:0044248 cellular catabolic process; GO:0010893 positive regulation of steroid biosynthetic process; GO:0032330 regulation of chondrocyte differentiation; GO:0009966 regulation of signal transduction; GO:0061035 regulation of cartilage development; GO:0060192 negative regulation of lipase activity; GO:0045861 negative regulation of proteolysis; GO:0032332 positive regulation of chondrocyte differentiation; GO:0071371 cellular response to gonadotropin stimulus; GO:0010033 response to organic substance; GO:0030162 regulation of proteolysis; GO:0007584 response to nutrient; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1902932 positive regulation of alcohol biosynthetic process; GO:0031325 positive regulation of cellular metabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0048584 positive regulation of response to stimulus; GO:0043412 macromolecule modification; GO:0050793 regulation of developmental process; GO:1901564 organonitrogen compound metabolic process; GO:0046620 regulation of organ growth; GO:0090030 regulation of steroid hormone biosynthetic process; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0010646 regulation of cell communication; GO:1901653 cellular response to peptide; GO:0050810 regulation of steroid biosynthetic process; GO:0009893 positive regulation of metabolic process; GO:0043543 protein acylation; GO:0090346 cellular organofluorine metabolic process; GO:0070887 cellular response to chemical stimulus; GO:0006629 lipid metabolic process; GO:0019395 fatty acid oxidation; GO:0046886 positive regulation of hormone biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0042126 nitrate metabolic process; GO:2000116 regulation of cysteine-type endopeptidase activity; GO:0018394 peptidyl-lysine acetylation; GO:0055114 oxidation-reduction process; GO:0048522 positive regulation of cellular process; GO:0006577 amino-acid betaine metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0071417 cellular response to organonitrogen compound; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0042221 response to chemical; GO:0043434 response to peptide hormone; GO:1901699 cellular response to nitrogen compound; GO:0032870 cellular response to hormone stimulus; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0009437 carnitine metabolic process; GO:0044092 negative regulation of molecular function; GO:0003420 regulation of growth plate cartilage chondrocyte proliferation; GO:0032352 positive regulation of hormone metabolic process; GO:0006082 organic acid metabolic process; GO:0052547 regulation of peptidase activity; GO:0036211 protein modification process; GO:2000026 regulation of multicellular organismal development; GO:0071466 cellular response to xenobiotic stimulus; GO:0018393 internal peptidyl-lysine acetylation; GO:0034440 lipid oxidation; GO:0040008 regulation of growth; GO:0043069 negative regulation of programmed cell death; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0031324 negative regulation of cellular metabolic process; GO:0046209 nitric oxide metabolic process; GO:0048638 regulation of developmental growth; GO:0050896 response to stimulus; GO:0051346 negative regulation of hydrolase activity; GO:0071704 organic substance metabolic process; GO:0034698 response to gonadotropin; GO:0018205 peptidyl-lysine modification; GO:0009991 response to extracellular stimulus; GO:0046885 regulation of hormone biosynthetic process; GO:2000027 regulation of organ morphogenesis; GO:0006805 xenobiotic metabolic process; GO:0043066 negative regulation of apoptotic process; GO:0072593 reactive oxygen species metabolic process; GO:0023056 positive regulation of signaling; GO:0032354 response to follicle-stimulating hormone; GO:0071375 cellular response to peptide hormone stimulus; GO:2000117 negative regulation of cysteine-type endopeptidase activity; GO:0032770 positive regulation of monooxygenase activity; GO:2001057 reactive nitrogen species metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0010647 positive regulation of cell communication; GO:0045880 positive regulation of smoothened signaling pathway; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0032350 regulation of hormone metabolic process; GO:0006475 internal protein amino acid acetylation; GO:0044712 single-organism catabolic process; GO:0045540 regulation of cholesterol biosynthetic process; GO:0070988 demethylation; GO:0006807 nitrogen compound metabolic process; GO:0006631 fatty acid metabolic process; GO:0048518 positive regulation of biological process; GO:0045834 positive regulation of lipid metabolic process; GO:0071372 cellular response to follicle-stimulating hormone stimulus; GO:0043085 positive regulation of catalytic activity; GO:0018193 peptidyl-amino acid modification; GO:0061036 positive regulation of cartilage development; GO:1901701 cellular response to oxygen-containing compound; GO:0051246 regulation of protein metabolic process; GO:0071495 cellular response to endogenous stimulus; GO:0022603 regulation of anatomical structure morphogenesis; GO:0019752 carboxylic acid metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0090031 positive regulation of steroid hormone biosynthetic process; GO:0031667 response to nutrient levels; GO:0009967 positive regulation of signal transduction; GO:0045542 positive regulation of cholesterol biosynthetic process; GO:0009725 response to hormone; GO:0009056 catabolic process; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044432 endoplasmic reticulum part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; ","GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:0016708 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor; GO:0047726 iron-cytochrome-c reductase activity; GO:1901265 nucleoside phosphate binding; GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor; GO:0050660 flavin adenine dinucleotide binding; GO:0043167 ion binding; GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0000166 nucleotide binding; GO:0016675 oxidoreductase activity, acting on a heme group of donors; GO:0048037 cofactor binding; GO:0016491 oxidoreductase activity; GO:0009055 electron carrier activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0003958 NADPH-hemoprotein reductase activity; GO:0097367 carbohydrate derivative binding; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0051213 dioxygenase activity; GO:0005488 binding; GO:0008941 nitric oxide dioxygenase activity; GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H; GO:0050661 NADP binding; GO:0043168 anion binding; GO:0010181 FMN binding; GO:0019899 enzyme binding; GO:0050662 coenzyme binding; GO:0036094 small molecule binding; ","K00327",null,null,"IPR001433; IPR017927; IPR017938; IPR023173; IPR008254; IPR029039; IPR003097; IPR001709; ","\"Oxidoreductase FAD/NAD(P)-binding; Ferredoxin reductase-type FAD-binding domain; Riboflavin synthase-like beta-barrel; NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain-3; Flavodoxin/nitric oxide synthase; Flavoprotein-like domain; FAD-binding, type 1; Flavoprotein pyridine nucleotide cytochrome reductase; \"\r"]
["P16455","Methylated-DNA--protein-cysteine methyltransferase OS=Homo sapiens OX=9606 GN=MGMT","MGMT",21.646,19.705,30.9,5,5,5,1.136,1.105,1.179,0.889,0.918,0.799,0.762,0.00402,"cytoplasm\r","GO:0010941 regulation of cell death; GO:0001101 response to acid chemical; GO:0048732 gland development; GO:0006266 DNA ligation; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0051593 response to folic acid; GO:0044237 cellular metabolic process; GO:0032259 methylation; GO:0006282 regulation of DNA repair; GO:0061180 mammary gland epithelium development; GO:0009605 response to external stimulus; GO:0035510 DNA dealkylation; GO:0008152 metabolic process; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0006979 response to oxidative stress; GO:0009719 response to endogenous stimulus; GO:0009314 response to radiation; GO:0034599 cellular response to oxidative stress; GO:0060644 mammary gland epithelial cell differentiation; GO:0071479 cellular response to ionizing radiation; GO:0043170 macromolecule metabolic process; GO:0033273 response to vitamin; GO:2001022 positive regulation of response to DNA damage stimulus; GO:0070887 cellular response to chemical stimulus; GO:0052548 regulation of endopeptidase activity; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0009888 tissue development; GO:0071214 cellular response to abiotic stimulus; GO:2000116 regulation of cysteine-type endopeptidase activity; GO:0080090 regulation of primary metabolic process; GO:0051054 positive regulation of DNA metabolic process; GO:0009636 response to toxic substance; GO:0044763 single-organism cellular process; GO:0006307 DNA dealkylation involved in DNA repair; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0048513 animal organ development; GO:0010243 response to organonitrogen compound; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0051336 regulation of hydrolase activity; GO:0080135 regulation of cellular response to stress; GO:0051052 regulation of DNA metabolic process; GO:0090304 nucleic acid metabolic process; GO:0050790 regulation of catalytic activity; GO:0006306 DNA methylation; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0044260 cellular macromolecule metabolic process; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0052547 regulation of peptidase activity; GO:0048856 anatomical structure development; GO:0060548 negative regulation of cell death; GO:0030855 epithelial cell differentiation; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0006305 DNA alkylation; GO:0033554 cellular response to stress; GO:0043069 negative regulation of programmed cell death; GO:0006725 cellular aromatic compound metabolic process; GO:2001020 regulation of response to DNA damage stimulus; GO:0009628 response to abiotic stimulus; GO:0006259 DNA metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0045471 response to ethanol; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0043067 regulation of programmed cell death; GO:1901700 response to oxygen-containing compound; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:0050896 response to stimulus; GO:0045739 positive regulation of DNA repair; GO:0030879 mammary gland development; GO:0071704 organic substance metabolic process; GO:0042493 response to drug; GO:0009991 response to extracellular stimulus; GO:0030154 cell differentiation; GO:0046483 heterocycle metabolic process; GO:0043066 negative regulation of apoptotic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0007275 multicellular organism development; GO:2000781 positive regulation of double-strand break repair; GO:0071478 cellular response to radiation; GO:0009987 cellular process; GO:0006304 DNA modification; GO:0006950 response to stress; GO:0048731 system development; GO:0006807 nitrogen compound metabolic process; GO:0097305 response to alcohol; GO:0071407 cellular response to organic cyclic compound; GO:0030162 regulation of proteolysis; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0007584 response to nutrient; GO:2000779 regulation of double-strand break repair; GO:0048518 positive regulation of biological process; GO:0006974 cellular response to DNA damage stimulus; GO:0010212 response to ionizing radiation; GO:0006281 DNA repair; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0043414 macromolecule methylation; GO:0031325 positive regulation of cellular metabolic process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0031667 response to nutrient levels; GO:0043412 macromolecule modification; GO:0048584 positive regulation of response to stimulus; GO:0044728 DNA methylation or demethylation; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031974 membrane-enclosed lumen; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0003677 DNA binding; GO:0008168 methyltransferase activity; GO:0009008 DNA-methyltransferase activity; GO:0043167 ion binding; GO:0016741 transferase activity, transferring one-carbon groups; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0008172 S-methyltransferase activity; GO:0003908 methylated-DNA-[protein]-cysteine S-methyltransferase activity; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005509 calcium ion binding; GO:0016740 transferase activity; ","K00567",null,null,"IPR011991; IPR008332; IPR014048; ","\"Winged helix-turn-helix DNA-binding domain; Methylguanine DNA methyltransferase, ribonuclease-like domain; Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding; \"\r"]
["P16615","Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 OS=Homo sapiens OX=9606 GN=ATP2A2","ATP2A2",114.76,175.58,25.6,27,44,21,0.917,0.88,1,1.068,1.059,1.073,1.144,0.0695,"plasma membrane\r","GO:0060627 regulation of vesicle-mediated transport; GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0022610 biological adhesion; GO:0043500 muscle adaptation; GO:0098900 regulation of action potential; GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0055065 metal ion homeostasis; GO:1903115 regulation of actin filament-based movement; GO:0007155 cell adhesion; GO:0008544 epidermis development; GO:0044057 regulation of system process; GO:0051716 cellular response to stimulus; GO:0044763 single-organism cellular process; GO:0019932 second-messenger-mediated signaling; GO:0007009 plasma membrane organization; GO:0032501 multicellular organismal process; GO:0006874 cellular calcium ion homeostasis; GO:1902803 regulation of synaptic vesicle transport; GO:1903779 regulation of cardiac conduction; GO:0006810 transport; GO:0010460 positive regulation of heart rate; GO:0048583 regulation of response to stimulus; GO:0014888 striated muscle adaptation; GO:0014897 striated muscle hypertrophy; GO:0098662 inorganic cation transmembrane transport; GO:0050794 regulation of cellular process; GO:0055001 muscle cell development; GO:0046907 intracellular transport; GO:0033554 cellular response to stress; GO:0034220 ion transmembrane transport; GO:0034976 response to endoplasmic reticulum stress; GO:0030001 metal ion transport; GO:0017157 regulation of exocytosis; GO:0045822 negative regulation of heart contraction; GO:1903523 negative regulation of blood circulation; GO:0048519 negative regulation of biological process; GO:0051239 regulation of multicellular organismal process; GO:0060341 regulation of cellular localization; GO:0019722 calcium-mediated signaling; GO:0061061 muscle structure development; GO:0051588 regulation of neurotransmitter transport; GO:0099131 ATP hydrolysis coupled ion transmembrane transport; GO:0048878 chemical homeostasis; GO:0070588 calcium ion transmembrane transport; GO:0006950 response to stress; GO:0051270 regulation of cellular component movement; GO:0050804 modulation of synaptic transmission; GO:0032970 regulation of actin filament-based process; GO:0006984 ER-nucleus signaling pathway; GO:1903515 calcium ion transport from cytosol to endoplasmic reticulum; GO:0055085 transmembrane transport; GO:0043502 regulation of muscle adaptation; GO:0006873 cellular ion homeostasis; GO:0006996 organelle organization; GO:0006811 ion transport; GO:0002027 regulation of heart rate; GO:0061024 membrane organization; GO:0032469 endoplasmic reticulum calcium ion homeostasis; GO:0051179 localization; GO:0070838 divalent metal ion transport; GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling; GO:0001505 regulation of neurotransmitter levels; GO:0010256 endomembrane system organization; GO:0003012 muscle system process; GO:0072503 cellular divalent inorganic cation homeostasis; GO:0090662 ATP hydrolysis coupled transmembrane transport; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:0014887 cardiac muscle adaptation; GO:0051046 regulation of secretion; GO:0044699 single-organism process; GO:0051241 negative regulation of multicellular organismal process; GO:0055119 relaxation of cardiac muscle; GO:0051234 establishment of localization; GO:0098901 regulation of cardiac muscle cell action potential; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0055117 regulation of cardiac muscle contraction; GO:0006979 response to oxidative stress; GO:0034599 cellular response to oxidative stress; GO:0086036 regulation of cardiac muscle cell membrane potential; GO:0060401 cytosolic calcium ion transport; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0009888 tissue development; GO:0098655 cation transmembrane transport; GO:0014898 cardiac muscle hypertrophy in response to stress; GO:0050801 ion homeostasis; GO:0055074 calcium ion homeostasis; GO:0098771 inorganic ion homeostasis; GO:1990036 calcium ion import into sarcoplasmic reticulum; GO:0019725 cellular homeostasis; GO:0032386 regulation of intracellular transport; GO:0090257 regulation of muscle system process; GO:1903530 regulation of secretion by cell; GO:0023052 signaling; GO:0046928 regulation of neurotransmitter secretion; GO:0006942 regulation of striated muscle contraction; GO:0042391 regulation of membrane potential; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0014896 muscle hypertrophy; GO:1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter; GO:0070509 calcium ion import; GO:0048856 anatomical structure development; GO:0072507 divalent inorganic cation homeostasis; GO:0016043 cellular component organization; GO:0014733 regulation of skeletal muscle adaptation; GO:0072511 divalent inorganic cation transport; GO:0003299 muscle hypertrophy in response to stress; GO:0033292 T-tubule organization; GO:1903522 regulation of blood circulation; GO:0030003 cellular cation homeostasis; GO:0008016 regulation of heart contraction; GO:0050896 response to stimulus; GO:0086004 regulation of cardiac muscle cell contraction; GO:0048468 cell development; GO:0055082 cellular chemical homeostasis; GO:0090075 relaxation of muscle; GO:2000300 regulation of synaptic vesicle exocytosis; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:0006812 cation transport; GO:0006816 calcium ion transport; GO:0055080 cation homeostasis; GO:0003300 cardiac muscle hypertrophy; GO:0070296 sarcoplasmic reticulum calcium ion transport; GO:0099132 ATP hydrolysis coupled cation transmembrane transport; GO:1903524 positive regulation of blood circulation; GO:0009987 cellular process; GO:0003008 system process; GO:0035556 intracellular signal transduction; GO:0098660 inorganic ion transmembrane transport; GO:0051049 regulation of transport; GO:0006937 regulation of muscle contraction; GO:0044802 single-organism membrane organization; GO:1903305 regulation of regulated secretory pathway; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0014883 transition between fast and slow fiber; GO:0045823 positive regulation of heart contraction; GO:0044767 single-organism developmental process; GO:0002026 regulation of the force of heart contraction; GO:0032470 positive regulation of endoplasmic reticulum calcium ion concentration; GO:0042692 muscle cell differentiation; GO:0006875 cellular metal ion homeostasis; GO:0017158 regulation of calcium ion-dependent exocytosis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0090534 calcium ion-transporting ATPase complex; GO:0031090 organelle membrane; GO:0019898 extrinsic component of membrane; GO:0071944 cell periphery; GO:0014801 longitudinal sarcoplasmic reticulum; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0031234 extrinsic component of cytoplasmic side of plasma membrane; GO:0016528 sarcoplasm; GO:0005623 cell; GO:0009898 cytoplasmic side of plasma membrane; GO:0098562 cytoplasmic side of membrane; GO:0090533 cation-transporting ATPase complex; GO:0044422 organelle part; GO:0033017 sarcoplasmic reticulum membrane; GO:0098533 ATPase dependent transmembrane transport complex; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0048471 perinuclear region of cytoplasm; GO:1990351 transporter complex; GO:0043227 membrane-bounded organelle; GO:0031094 platelet dense tubular network; GO:0005789 endoplasmic reticulum membrane; GO:0043233 organelle lumen; GO:0098552 side of membrane; GO:0043229 intracellular organelle; GO:0031226 intrinsic component of plasma membrane; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0019897 extrinsic component of plasma membrane; GO:0016529 sarcoplasmic reticulum; GO:0012506 vesicle membrane; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0031095 platelet dense tubular network membrane; GO:1902495 transmembrane transporter complex; GO:0016021 integral component of membrane; GO:0045202 synapse; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0044432 endoplasmic reticulum part; GO:0097470 ribbon synapse; GO:1904949 ATPase complex; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0031775 lutropin-choriogonadotropic hormone receptor binding; GO:0042625 ATPase coupled ion transmembrane transporter activity; GO:1901265 nucleoside phosphate binding; GO:0005102 receptor binding; GO:0015399 primary active transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0016887 ATPase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0046873 metal ion transmembrane transporter activity; GO:0016462 pyrophosphatase activity; GO:0019829 cation-transporting ATPase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0043492 ATPase activity, coupled to movement of substances; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; GO:0001664 G-protein coupled receptor binding; GO:0044548 S100 protein binding; GO:0008022 protein C-terminus binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0022890 inorganic cation transmembrane transporter activity; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0086039 calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005215 transporter activity; GO:0022804 active transmembrane transporter activity; GO:0005524 ATP binding; GO:0015075 ion transmembrane transporter activity; GO:0022853 active ion transmembrane transporter activity; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity; GO:0072509 divalent inorganic cation transmembrane transporter activity; GO:0015662 ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism; GO:0005388 calcium-transporting ATPase activity; GO:0042626 ATPase activity, coupled to transmembrane movement of substances; GO:0042623 ATPase activity, coupled; GO:0046872 metal ion binding; GO:0015085 calcium ion transmembrane transporter activity; GO:0032555 purine ribonucleotide binding; GO:0005509 calcium ion binding; GO:0001883 purine nucleoside binding; GO:0019899 enzyme binding; GO:0008324 cation transmembrane transporter activity; GO:0036094 small molecule binding; GO:0022857 transmembrane transporter activity; ","K05853","ATP2A; Ca2+ transporting ATPase, sarcoplasmic/endoplasmic reticulum [EC:3.6.3.8]","hsa04260 Cardiac muscle contraction - Homo sapiens (human); hsa05010 Alzheimer's disease - Homo sapiens (human); hsa05414 Dilated cardiomyopathy (DCM) - Homo sapiens (human); hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human); hsa04972 Pancreatic secretion - Homo sapiens (human); hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human); hsa04020 Calcium signaling pathway - Homo sapiens (human); hsa04024 cAMP signaling pathway - Homo sapiens (human); hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human); hsa05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human); hsa05410 Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human); ","IPR023298; IPR004014; IPR008250; IPR023299; IPR006068; IPR023214; ","\"P-type ATPase,  transmembrane domain; Cation-transporting P-type ATPase, N-terminal; P-type ATPase, A  domain; P-type ATPase, cytoplasmic domain N; Cation-transporting P-type ATPase, C-terminal; HAD-like domain; \"\r"]
["P16671","Platelet glycoprotein 4 OS=Homo sapiens OX=9606 GN=CD36","CD36",53.053,24.332,21,7,11,7,1.115,0.997,1.127,0.953,0.926,0.938,0.87,0.0261,"plasma membrane\r",{"$cut":{"chars":19837,"head":"GO:0044700 single organism signaling; GO:0010744 positive regulation of macrophage derived foam cell differentiation; GO:0060100 positive regulation of phagocytosis, engulfment; GO:0032680 regulation of tumor necrosis factor production; GO:0098542 defense response to other organism; GO:0090317 negative regulation of intracellular protein transport; GO:0031347 regulation of defense response; GO:0044237 cellular metabolic process; GO:0009607 response to biotic stimulus; GO:0055098 response to low-density lipoprotein particle; GO:0008152 metabolic process; GO:0015718 monocarboxylic acid transport; GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling; GO:0055065 metal ion homeostasis; GO:0009306 protein secretion; GO:0055094 response to lipoprotein particle; GO:1900181 negative regulation of protein localization to nucleus; GO:0030194 positive regulation of blood coagulation; GO:0051051 negative regulation of transport; GO:0042325 regulation of phosphorylation; GO:0001954 positive regulation of cell-matrix adhesion; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0019932 second-messenger-mediated signaling; GO:0019934 cGMP-mediated signaling; GO:0006874 cellular calcium ion homeostasis; GO:0071396 cellular response to lipid; GO:0010811 positive regulation of cell-substrate adhesion; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:1900225 regulation of NLRP3 inflammasome complex assembly; GO:0006810 transport; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0035634 response to stilbenoid; GO:0080135 regulation of cellular response to stress; GO:1900048 positive regulation of hemostasis; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0051223 regulation of protein transport; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0002755 MyD88-dependent toll-like receptor signaling pathway; GO:0050701 interleukin-1 secretion; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0044707 single-multicellular organism process; GO:0002718 regulation of cytokine production involved in immune response; GO:0001819 positive regulation of cytokine production; GO:0060099 regulation of phagocytosis, engulfment; GO:1901700 response to oxygen-containing compound; GO:0002576 platelet degranulation; GO:0071221 cellular response to bacterial lipopeptide; GO:0048519 negative regulation of biological process; GO:0044146 negative regulation of growth of symbiont involved in interaction with host; GO:0042990 regulation of transcription factor import into nucleus; GO:0045892 negative regulation of transcription, DNA-templated; GO:0009889 regulation of biosynthetic process; GO:2000121 regulation of removal of superoxide radicals; GO:0050778 positive regulation of immune response; GO:0048878 chemical homeostasis; GO:0030100 regulation of endocytosis; GO:0045785 positive regulation of cell adhesion; GO:0006950 response to stress; GO:0032496 response to lipopolysaccharide; GO:0010884 positive regulation of lipid storage; GO:0050766 positive regulation of phagocytosis; GO:0002376 immune system process; GO:0032101 regulation of response to external stimulus; GO:0010876 lipid localization; GO:0034381 plasma lipoprotein particle clearance; GO:0010033 response to organic substance; GO:0070508 cholesterol import; GO:0015849 organic acid transport; GO:0060907 positive regulation of macrophage cytokine production; GO:0002263 cell activation involved in immune response; GO:0045055 regulated exocytosis; GO:0009890 negative regulation of biosynthetic process; GO:0061041 regulation of wound healing; GO:0010883 regulation of lipid storage; GO:0001816 cytokine production; GO:0031325 positive regulation of cellular metabolic process; GO:0071219 cellular response to molecule of bacterial origin; GO:0006955 immune response; GO:1903034 regulation of response to wounding; GO:1903827 regulation of cellular protein localizati"}},"GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0098862 cluster of actin-based cell projections; GO:0016324 apical plasma membrane; GO:0005903 brush border; GO:0009897 external side of plasma membrane; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0098857 membrane microdomain; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0098590 plasma membrane region; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0099503 secretory vesicle; GO:0098589 membrane region; GO:0030141 secretory granule; GO:0045121 membrane raft; GO:0030139 endocytic vesicle; GO:0043227 membrane-bounded organelle; GO:0035579 specific granule membrane; GO:0045177 apical part of cell; GO:0031092 platelet alpha granule membrane; GO:0098552 side of membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0031226 intrinsic component of plasma membrane; GO:0098588 bounding membrane of organelle; GO:0030666 endocytic vesicle membrane; GO:0031526 brush border membrane; GO:0044446 intracellular organelle part; GO:0045335 phagocytic vesicle; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0044463 cell projection part; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0030667 secretory granule membrane; GO:0044459 plasma membrane part; GO:0042581 specific granule; GO:0031253 cell projection membrane; GO:0009986 cell surface; GO:0031091 platelet alpha granule; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:0038023 signaling receptor activity; GO:0019838 growth factor binding; GO:0044877 macromolecular complex binding; GO:0038024 cargo receptor activity; GO:0071813 lipoprotein particle binding; GO:0005515 protein binding; GO:0070892 lipoteichoic acid receptor activity; GO:0004871 signal transducer activity; GO:0050431 transforming growth factor beta binding; GO:0019955 cytokine binding; GO:0030228 lipoprotein particle receptor activity; GO:0060089 molecular transducer activity; GO:0030169 low-density lipoprotein particle binding; GO:0004872 receptor activity; GO:0070053 thrombospondin receptor activity; GO:0008035 high-density lipoprotein particle binding; GO:0005488 binding; GO:0008289 lipid binding; GO:0005041 low-density lipoprotein receptor activity; GO:0038187 pattern recognition receptor activity; GO:0071814 protein-lipid complex binding; GO:0008329 signaling pattern recognition receptor activity; ","K06259","CD36; CD36 antigen","hsa05144 Malaria - Homo sapiens (human); hsa04920 Adipocytokine signaling pathway - Homo sapiens (human); hsa03320 PPAR signaling pathway - Homo sapiens (human); hsa04640 Hematopoietic cell lineage - Homo sapiens (human); hsa04979 Cholesterol metabolism - Homo sapiens (human); hsa04152 AMPK signaling pathway - Homo sapiens (human); hsa04975 Fat digestion and absorption - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); hsa04512 ECM-receptor interaction - Homo sapiens (human); hsa04931 Insulin resistance - Homo sapiens (human); "]
["P16885","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 OS=Homo sapiens OX=9606 GN=PLCG2","PLCG2",147.87,5.1538,2.1,3,3,3,0.983,1.015,1.005,1.035,0.907,1.066,1.002,0.99,"nucleus\r","GO:0044700 single organism signaling; GO:0060627 regulation of vesicle-mediated transport; GO:0032481 positive regulation of type I interferon production; GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0010941 regulation of cell death; GO:0045321 leukocyte activation; GO:0002220 innate immune response activating cell surface receptor signaling pathway; GO:0007166 cell surface receptor signaling pathway; GO:0006066 alcohol metabolic process; GO:0044255 cellular lipid metabolic process; GO:0031347 regulation of defense response; GO:1904427 positive regulation of calcium ion transmembrane transport; GO:0044237 cellular metabolic process; GO:0009607 response to biotic stimulus; GO:0008610 lipid biosynthetic process; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:1901019 regulation of calcium ion transmembrane transporter activity; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0060402 calcium ion transport into cytosol; GO:0055065 metal ion homeostasis; GO:0032414 positive regulation of ion transmembrane transporter activity; GO:1901339 regulation of store-operated calcium channel activity; GO:0016055 Wnt signaling pathway; GO:0044765 single-organism transport; GO:0051716 cellular response to stimulus; GO:0048259 regulation of receptor-mediated endocytosis; GO:0002758 innate immune response-activating signal transduction; GO:0030168 platelet activation; GO:0044281 small molecule metabolic process; GO:0043269 regulation of ion transport; GO:0044763 single-organism cellular process; GO:0002335 mature B cell differentiation; GO:0002520 immune system development; GO:1901617 organic hydroxy compound biosynthetic process; GO:0019932 second-messenger-mediated signaling; GO:0031323 regulation of cellular metabolic process; GO:0030183 B cell differentiation; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0006874 cellular calcium ion homeostasis; GO:0050776 regulation of immune response; GO:0034762 regulation of transmembrane transport; GO:0006810 transport; GO:0090407 organophosphate biosynthetic process; GO:1901575 organic substance catabolic process; GO:0048513 animal organ development; GO:0002223 stimulatory C-type lectin receptor signaling pathway; GO:0007267 cell-cell signaling; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:2001257 regulation of cation channel activity; GO:0010604 positive regulation of macromolecule metabolic process; GO:1901021 positive regulation of calcium ion transmembrane transporter activity; GO:0002682 regulation of immune system process; GO:0050817 coagulation; GO:0032412 regulation of ion transmembrane transporter activity; GO:0060548 negative regulation of cell death; GO:0098662 inorganic cation transmembrane transport; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0034764 positive regulation of transmembrane transport; GO:0034220 ion transmembrane transport; GO:1901615 organic hydroxy compound metabolic process; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0006661 phosphatidylinositol biosynthetic process; GO:0030001 metal ion transport; GO:0001819 positive regulation of cytokine production; GO:1901700 response to oxygen-containing compound; GO:0043067 regulation of programmed cell death; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:1901341 positive regulation of store-operated calcium channel activity; GO:0032844 regulation of homeostatic process; GO:0051239 regulation of multicellular organismal process; GO:0030098 lymphocyte differentiation; GO:0031349 positive regulation of defense response; GO:1902578 single-organism localization; GO:0019722 calcium-mediated signaling; GO:0010959 regulation of metal ion transport; GO:0044248 cellular catabolic process; GO:0007275 multicellular organism development; GO:0038093 Fc receptor signaling pathway; GO:0050778 positive regulation of immune response; GO:0032409 regulation of transporter activity; GO:1904062 regulation of cation transmembrane transport; GO:0009617 response to bacterium; GO:0051209 release of sequestered calcium ion into cytosol; GO:0048878 chemical homeostasis; GO:0051928 positive regulation of calcium ion transport; GO:0070588 calcium ion transmembrane transport; GO:0002253 activation of immune response; GO:0016042 lipid catabolic process; GO:0002285 lymphocyte activation involved in immune response; GO:0051282 regulation of sequestering of calcium ion; GO:0030100 regulation of endocytosis; GO:0006950 response to stress; GO:0044711 single-organism biosynthetic process; GO:0032496 response to lipopolysaccharide; GO:0048731 system development; GO:0032959 inositol trisphosphate biosynthetic process; GO:0016192 vesicle-mediated transport; GO:0051924 regulation of calcium ion transport; GO:0046165 alcohol biosynthetic process; GO:0002376 immune system process; GO:1902656 calcium ion import into cytosol; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0002263 cell activation involved in immune response; GO:0019751 polyol metabolic process; GO:1901576 organic substance biosynthetic process; GO:2001259 positive regulation of cation channel activity; GO:0043270 positive regulation of ion transport; GO:0055085 transmembrane transport; GO:1904064 positive regulation of cation transmembrane transport; GO:0032957 inositol trisphosphate metabolic process; GO:0006873 cellular ion homeostasis; GO:0006793 phosphorus metabolic process; GO:0006811 ion transport; GO:0031325 positive regulation of cellular metabolic process; GO:0044283 small molecule biosynthetic process; GO:0001775 cell activation; GO:0044242 cellular lipid catabolic process; GO:0019637 organophosphate metabolic process; GO:0043647 inositol phosphate metabolic process; GO:0006644 phospholipid metabolic process; GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis; GO:0006955 immune response; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0007204 positive regulation of cytosolic calcium ion concentration; GO:0070838 divalent metal ion transport; GO:0046486 glycerolipid metabolic process; GO:0072503 cellular divalent inorganic cation homeostasis; GO:0002092 positive regulation of receptor internalization; GO:0038094 Fc-gamma receptor signaling pathway; GO:0048869 cellular developmental process; GO:0008654 phospholipid biosynthetic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0006796 phosphate-containing compound metabolic process; GO:0006909 phagocytosis; GO:0051234 establishment of localization; GO:0009611 response to wounding; GO:0051130 positive regulation of cellular component organization; GO:0009395 phospholipid catabolic process; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0045088 regulation of innate immune response; GO:0009893 positive regulation of metabolic process; GO:0002313 mature B cell differentiation involved in immune response; GO:0006650 glycerophospholipid metabolic process; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0046488 phosphatidylinositol metabolic process; GO:0060401 cytosolic calcium ion transport; GO:0050851 antigen receptor-mediated signaling pathway; GO:0006629 lipid metabolic process; GO:0032502 developmental process; GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis; GO:0010468 regulation of gene expression; GO:0097553 calcium ion transmembrane import into cytosol; GO:0098655 cation transmembrane transport; GO:0050801 ion homeostasis; GO:0002521 leukocyte differentiation; GO:0002237 response to molecule of bacterial origin; GO:0055074 calcium ion homeostasis; GO:0098771 inorganic ion homeostasis; GO:0048522 positive regulation of cellular process; GO:0019725 cellular homeostasis; GO:0022898 regulation of transmembrane transporter activity; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0002312 B cell activation involved in immune response; GO:0051050 positive regulation of transport; GO:0198738 cell-cell signaling by wnt; GO:0050853 B cell receptor signaling pathway; GO:0002316 follicular B cell differentiation; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0034767 positive regulation of ion transmembrane transport; GO:0032237 activation of store-operated calcium channel activity; GO:0046474 glycerophospholipid biosynthetic process; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0070509 calcium ion import; GO:0002431 Fc receptor mediated stimulatory signaling pathway; GO:0048856 anatomical structure development; GO:0072507 divalent inorganic cation homeostasis; GO:0048260 positive regulation of receptor-mediated endocytosis; GO:0002218 activation of innate immune response; GO:0043069 negative regulation of programmed cell death; GO:0032479 regulation of type I interferon production; GO:0072511 divalent inorganic cation transport; GO:2000021 regulation of ion homeostasis; GO:0032411 positive regulation of transporter activity; GO:0002252 immune effector process; GO:0046434 organophosphate catabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0045807 positive regulation of endocytosis; GO:0032958 inositol phosphate biosynthetic process; GO:0051480 regulation of cytosolic calcium ion concentration; GO:0030003 cellular cation homeostasis; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0007599 hemostasis; GO:0055082 cellular chemical homeostasis; GO:0071704 organic substance metabolic process; GO:0033993 response to lipid; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:0055080 cation homeostasis; GO:0006816 calcium ion transport; GO:0006812 cation transport; GO:1903169 regulation of calcium ion transmembrane transport; GO:0002757 immune response-activating signal transduction; GO:0009987 cellular process; GO:0042113 B cell activation; GO:0002090 regulation of receptor internalization; GO:0045089 positive regulation of innate immune response; GO:0050878 regulation of body fluid levels; GO:0035556 intracellular signal transduction; GO:0098660 inorganic ion transmembrane transport; GO:0051049 regulation of transport; GO:0044712 single-organism catabolic process; GO:0046649 lymphocyte activation; GO:0032845 negative regulation of homeostatic process; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0048534 hematopoietic or lymphoid organ development; GO:0030097 hemopoiesis; GO:0044249 cellular biosynthetic process; GO:0051283 negative regulation of sequestering of calcium ion; GO:0045017 glycerolipid biosynthetic process; GO:0051641 cellular localization; GO:0002366 leukocyte activation involved in immune response; GO:0050852 T cell receptor signaling pathway; GO:0034765 regulation of ion transmembrane transport; GO:0042060 wound healing; GO:0044767 single-organism developmental process; GO:0002684 positive regulation of immune system process; GO:0038095 Fc-epsilon receptor signaling pathway; GO:0001817 regulation of cytokine production; GO:0046173 polyol biosynthetic process; GO:0006875 cellular metal ion homeostasis; GO:0051128 regulation of cellular component organization; GO:0009056 catabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0004435 phosphatidylinositol phospholipase C activity; GO:0042578 phosphoric ester hydrolase activity; GO:0003824 catalytic activity; GO:0004629 phospholipase C activity; GO:0005488 binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0004620 phospholipase activity; GO:0008081 phosphoric diester hydrolase activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0016298 lipase activity; GO:0004871 signal transducer activity; ","K05859","PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]","hsa04072 Phospholipase D signaling pathway - Homo sapiens (human); hsa04650 Natural killer cell mediated cytotoxicity - Homo sapiens (human); hsa04625 C-type lectin receptor signaling pathway - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa04662 B cell receptor signaling pathway - Homo sapiens (human); hsa04014 Ras signaling pathway - Homo sapiens (human); hsa05110 Vibrio cholerae infection - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa05206 MicroRNAs in cancer - Homo sapiens (human); hsa00562 Inositol phosphate metabolism - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa04380 Osteoclast differentiation - Homo sapiens (human); hsa04070 Phosphatidylinositol signaling system - Homo sapiens (human); hsa04933 AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human); hsa04611 Platelet activation - Homo sapiens (human); hsa01521 EGFR tyrosine kinase inhibitor resistance - Homo sapiens (human); hsa04064 NF-kappa B signaling pathway - Homo sapiens (human); hsa05120 Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); hsa04722 Neurotrophin signaling pathway - Homo sapiens (human); hsa04370 VEGF signaling pathway - Homo sapiens (human); hsa04020 Calcium signaling pathway - Homo sapiens (human); hsa05167 Kaposi's sarcoma-associated herpesvirus infection - Homo sapiens (human); hsa05225 Hepatocellular carcinoma - Homo sapiens (human); hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human); hsa04670 Leukocyte transendothelial migration - Homo sapiens (human); hsa04750 Inflammatory mediator regulation of TRP channels - Homo sapiens (human); hsa04666 Fc gamma R-mediated phagocytosis - Homo sapiens (human); hsa05223 Non-small cell lung cancer - Homo sapiens (human); hsa04664 Fc epsilon RI signaling pathway - Homo sapiens (human); hsa04066 HIF-1 signaling pathway - Homo sapiens (human); hsa05214 Glioma - Homo sapiens (human); hsa04012 ErbB signaling pathway - Homo sapiens (human); hsa04360 Axon guidance - Homo sapiens (human); ","IPR000909; IPR001452; IPR000980; IPR017946; IPR011993; IPR011992; IPR000008; IPR001711; IPR001849; ","\"Phosphatidylinositol-specific phospholipase C, X domain; SH3 domain; SH2 domain; PLC-like phosphodiesterase, TIM beta/alpha-barrel domain; PH domain-like; EF-hand domain pair; C2 domain; Phospholipase C, phosphatidylinositol-specific, Y domain; Pleckstrin homology domain; \"\r"]
["P16930","Fumarylacetoacetase OS=Homo sapiens OX=9606 GN=FAH","FAH",46.374,32.076,18.1,6,9,6,1.241,1.093,1.107,0.893,0.87,0.868,0.765,2.98E-3,"cytoplasm\r","GO:1902222 erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process; GO:1901606 alpha-amino acid catabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006559 L-phenylalanine catabolic process; GO:0071704 organic substance metabolic process; GO:0006572 tyrosine catabolic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0044248 cellular catabolic process; GO:1901361 organic cyclic compound catabolic process; GO:1902221 erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process; GO:0009987 cellular process; GO:0006570 tyrosine metabolic process; GO:0009064 glutamine family amino acid metabolic process; GO:0009072 aromatic amino acid family metabolic process; GO:0009074 aromatic amino acid family catabolic process; GO:0044712 single-organism catabolic process; GO:0044281 small molecule metabolic process; GO:0006525 arginine metabolic process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0044282 small molecule catabolic process; GO:0044238 primary metabolic process; GO:1901605 alpha-amino acid metabolic process; GO:0046395 carboxylic acid catabolic process; GO:0006558 L-phenylalanine metabolic process; GO:0019439 aromatic compound catabolic process; GO:1901575 organic substance catabolic process; GO:1901565 organonitrogen compound catabolic process; GO:0044710 single-organism metabolic process; GO:0009065 glutamine family amino acid catabolic process; GO:0016054 organic acid catabolic process; GO:0019752 carboxylic acid metabolic process; GO:0009063 cellular amino acid catabolic process; GO:0006082 organic acid metabolic process; GO:0009056 catabolic process; GO:0043436 oxoacid metabolic process; GO:0006527 arginine catabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0004334 fumarylacetoacetase activity; GO:0016787 hydrolase activity; GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances; ","K01555","FAH; fumarylacetoacetase [EC:3.7.1.2]","hsa00350 Tyrosine metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR011234; IPR015377; ","\"Fumarylacetoacetase, C-terminal-related; Fumarylacetoacetase, N-terminal; \"\r"]
["P16949","Stathmin OS=Homo sapiens OX=9606 GN=STMN1","STMN1",17.302,17.392,38.9,8,16,5,0.787,0.815,0.749,1.174,1.217,1.241,1.545,1.21E-4,"nucleus\r","GO:0044700 single organism signaling; GO:0031111 negative regulation of microtubule polymerization or depolymerization; GO:0031109 microtubule polymerization or depolymerization; GO:0007420 brain development; GO:0007067 mitotic nuclear division; GO:0051129 negative regulation of cellular component organization; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0032989 cellular component morphogenesis; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0031110 regulation of microtubule polymerization or depolymerization; GO:0009607 response to biotic stimulus; GO:0043241 protein complex disassembly; GO:0009605 response to external stimulus; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0032990 cell part morphogenesis; GO:0032879 regulation of localization; GO:0048858 cell projection morphogenesis; GO:0032271 regulation of protein polymerization; GO:0060322 head development; GO:0051493 regulation of cytoskeleton organization; GO:0044419 interspecies interaction between organisms; GO:0031333 negative regulation of protein complex assembly; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0071822 protein complex subunit organization; GO:0048699 generation of neurons; GO:0051494 negative regulation of cytoskeleton organization; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0048812 neuron projection morphogenesis; GO:0031113 regulation of microtubule polymerization; GO:0051272 positive regulation of cellular component movement; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0000902 cell morphogenesis; GO:0032886 regulation of microtubule-based process; GO:0010639 negative regulation of organelle organization; GO:1902589 single-organism organelle organization; GO:0000226 microtubule cytoskeleton organization; GO:0048513 animal organ development; GO:0043254 regulation of protein complex assembly; GO:0050789 regulation of biological process; GO:0030030 cell projection organization; GO:0007417 central nervous system development; GO:1902904 negative regulation of supramolecular fiber organization; GO:1902850 microtubule cytoskeleton organization involved in mitosis; GO:0051301 cell division; GO:0097435 supramolecular fiber organization; GO:0048856 anatomical structure development; GO:0009615 response to virus; GO:1902903 regulation of supramolecular fiber organization; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0007019 microtubule depolymerization; GO:0048285 organelle fission; GO:0007051 spindle organization; GO:0044087 regulation of cellular component biogenesis; GO:0043207 response to external biotic stimulus; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:1903047 mitotic cell cycle process; GO:0048468 cell development; GO:0000904 cell morphogenesis involved in differentiation; GO:0031115 negative regulation of microtubule polymerization; GO:0009653 anatomical structure morphogenesis; GO:0030154 cell differentiation; GO:0000910 cytokinesis; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0016032 viral process; GO:0007409 axonogenesis; GO:0043624 cellular protein complex disassembly; GO:0007275 multicellular organism development; GO:0007052 mitotic spindle organization; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0051261 protein depolymerization; GO:0070507 regulation of microtubule cytoskeleton organization; GO:0035556 intracellular signal transduction; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0032984 macromolecular complex disassembly; GO:0000281 mitotic cytokinesis; GO:0033043 regulation of organelle organization; GO:0031175 neuron projection development; GO:0007017 microtubule-based process; GO:0048518 positive regulation of biological process; GO:0043933 macromolecular complex subunit organization; GO:0061564 axon development; GO:0030182 neuron differentiation; GO:0061640 cytoskeleton-dependent cytokinesis; GO:0044767 single-organism developmental process; GO:0006996 organelle organization; GO:0000280 nuclear division; GO:0022411 cellular component disassembly; GO:0022402 cell cycle process; GO:0051128 regulation of cellular component organization; GO:0032272 negative regulation of protein polymerization; GO:0007049 cell cycle; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042995 cell projection; GO:0044421 extracellular region part; GO:0099513 polymeric cytoskeletal fiber; GO:0005874 microtubule; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044424 intracellular part; GO:0099512 supramolecular fiber; GO:0005829 cytosol; GO:0005623 cell; GO:0099080 supramolecular complex; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0099081 supramolecular polymer; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005856 cytoskeleton; GO:0043226 organelle; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0015631 tubulin binding; GO:0005515 protein binding; GO:0008092 cytoskeletal protein binding; GO:0004871 signal transducer activity; GO:0005488 binding; ","K04381","STMN1; stathmin","hsa04010 MAPK signaling pathway - Homo sapiens (human); hsa05206 MicroRNAs in cancer - Homo sapiens (human); "]
["P16989","Y-box-binding protein 3 OS=Homo sapiens OX=9606 GN=YBX3","YBX3",40.089,29.854,19.4,5,8,3,0.758,0.925,0.692,1.263,1.118,1.163,1.492,0.0119,"nucleus\r","GO:0065008 regulation of biological quality; GO:0060544 regulation of necroptotic process; GO:0010941 regulation of cell death; GO:0032270 positive regulation of cellular protein metabolic process; GO:0022414 reproductive process; GO:0043009 chordate embryonic development; GO:0097659 nucleic acid-templated transcription; GO:0010608 posttranscriptional regulation of gene expression; GO:0043489 RNA stabilization; GO:0008584 male gonad development; GO:0009891 positive regulation of biosynthetic process; GO:1901862 negative regulation of muscle tissue development; GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress; GO:0044237 cellular metabolic process; GO:0071345 cellular response to cytokine stimulus; GO:0045927 positive regulation of growth; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0060546 negative regulation of necroptotic process; GO:0045843 negative regulation of striated muscle tissue development; GO:0044702 single organism reproductive process; GO:0043170 macromolecule metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0009790 embryo development; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0003006 developmental process involved in reproduction; GO:0071214 cellular response to abiotic stimulus; GO:0080090 regulation of primary metabolic process; GO:0000122 negative regulation of transcription from RNA polymerase II promoter; GO:0019953 sexual reproduction; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:2001234 negative regulation of apoptotic signaling pathway; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048635 negative regulation of muscle organ development; GO:0048513 animal organ development; GO:0080135 regulation of cellular response to stress; GO:1902532 negative regulation of intracellular signal transduction; GO:0001701 in utero embryonic development; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0071470 cellular response to osmotic stress; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0051094 positive regulation of developmental process; GO:0048609 multicellular organismal reproductive process; GO:0060548 negative regulation of cell death; GO:1901362 organic cyclic compound biosynthetic process; GO:0048255 mRNA stabilization; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0000003 reproduction; GO:0050794 regulation of cellular process; GO:0048641 regulation of skeletal muscle tissue development; GO:0033554 cellular response to stress; GO:0044707 single-multicellular organism process; GO:0009628 response to abiotic stimulus; GO:0008406 gonad development; GO:0043067 regulation of programmed cell death; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0080134 regulation of response to stress; GO:0051239 regulation of multicellular organismal process; GO:0043487 regulation of RNA stability; GO:0045892 negative regulation of transcription, DNA-templated; GO:0023057 negative regulation of signaling; GO:0046483 heterocycle metabolic process; GO:0010648 negative regulation of cell communication; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0007548 sex differentiation; GO:0007275 multicellular organism development; GO:0061458 reproductive system development; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0009966 regulation of signal transduction; GO:0070935 3'-UTR-mediated mRNA stabilization; GO:1902531 regulation of intracellular signal transduction; GO:0006950 response to stress; GO:0007283 spermatogenesis; GO:0048731 system development; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0034248 regulation of cellular amide metabolic process; GO:0009890 negative regulation of biosynthetic process; GO:0071474 cellular hyperosmotic response; GO:0051247 positive regulation of protein metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0046546 development of primary male sexual characteristics; GO:0031328 positive regulation of cellular biosynthetic process; GO:0050793 regulation of developmental process; GO:0046620 regulation of organ growth; GO:0051093 negative regulation of developmental process; GO:0009968 negative regulation of signal transduction; GO:2000765 regulation of cytoplasmic translation; GO:0023051 regulation of signaling; GO:0048634 regulation of muscle organ development; GO:0044699 single-organism process; GO:0051241 negative regulation of multicellular organismal process; GO:0009058 biosynthetic process; GO:0051253 negative regulation of RNA metabolic process; GO:2001233 regulation of apoptotic signaling pathway; GO:2001141 regulation of RNA biosynthetic process; GO:0010646 regulation of cell communication; GO:2001243 negative regulation of intrinsic apoptotic signaling pathway; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0047484 regulation of response to osmotic stress; GO:0034612 response to tumor necrosis factor; GO:0070887 cellular response to chemical stimulus; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0006970 response to osmotic stress; GO:0048639 positive regulation of developmental growth; GO:0034097 response to cytokine; GO:0031326 regulation of cellular biosynthetic process; GO:0045727 positive regulation of translation; GO:0048608 reproductive structure development; GO:0060547 negative regulation of necrotic cell death; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0046622 positive regulation of organ growth; GO:0010605 negative regulation of macromolecule metabolic process; GO:0016070 RNA metabolic process; GO:0009566 fertilization; GO:0016202 regulation of striated muscle tissue development; GO:0032268 regulation of cellular protein metabolic process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:1902679 negative regulation of RNA biosynthetic process; GO:0019222 regulation of metabolic process; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0043069 negative regulation of programmed cell death; GO:0040008 regulation of growth; GO:0006725 cellular aromatic compound metabolic process; GO:0071356 cellular response to tumor necrosis factor; GO:0060255 regulation of macromolecule metabolic process; GO:0046661 male sex differentiation; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0048638 regulation of developmental growth; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0048642 negative regulation of skeletal muscle tissue development; GO:0043066 negative regulation of apoptotic process; GO:0009266 response to temperature stimulus; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0045137 development of primary sexual characteristics; GO:0010939 regulation of necrotic cell death; GO:1902218 regulation of intrinsic apoptotic signaling pathway in response to osmotic stress; GO:0006355 regulation of transcription, DNA-templated; GO:0048232 male gamete generation; GO:0010629 negative regulation of gene expression; GO:0009792 embryo development ending in birth or egg hatching; GO:1901861 regulation of muscle tissue development; GO:0006972 hyperosmotic response; GO:0006807 nitrogen compound metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:2000767 positive regulation of cytoplasmic translation; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0048518 positive regulation of biological process; GO:0043488 regulation of mRNA stability; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0007276 gamete generation; GO:0032504 multicellular organism reproduction; GO:0009409 response to cold; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006417 regulation of translation; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:2001242 regulation of intrinsic apoptotic signaling pathway; GO:0044703 multi-organism reproductive process; GO:0034250 positive regulation of cellular amide metabolic process; GO:0010467 gene expression; GO:0031327 negative regulation of cellular biosynthetic process; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005911 cell-cell junction; GO:0005829 cytosol; GO:0005623 cell; GO:0005923 bicellular tight junction; GO:0043296 apical junction complex; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0070160 occluding junction; GO:0005622 intracellular; GO:0044464 cell part; GO:0048471 perinuclear region of cytoplasm; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0005844 polysome; ","GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding; GO:0003690 double-stranded DNA binding; GO:0003697 single-stranded DNA binding; GO:0005515 protein binding; GO:0003700 transcription factor activity, sequence-specific DNA binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0000975 regulatory region DNA binding; GO:0003729 mRNA binding; GO:0017016 Ras GTPase binding; GO:0005488 binding; GO:0001071 nucleic acid binding transcription factor activity; GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding; GO:0051020 GTPase binding; GO:0031267 small GTPase binding; GO:0003677 DNA binding; GO:0003723 RNA binding; GO:0017048 Rho GTPase binding; GO:0003714 transcription corepressor activity; GO:0000976 transcription regulatory region sequence-specific DNA binding; GO:0003730 mRNA 3'-UTR binding; GO:0001012 RNA polymerase II regulatory region DNA binding; GO:1990837 sequence-specific double-stranded DNA binding; GO:0043565 sequence-specific DNA binding; GO:0003712 transcription cofactor activity; GO:0001067 regulatory region nucleic acid binding; GO:0044212 transcription regulatory region DNA binding; GO:0003676 nucleic acid binding; GO:0000988 transcription factor activity, protein binding; GO:0019899 enzyme binding; ","K06099","CSDA; cold shock domain protein A","hsa04530 Tight junction - Homo sapiens (human); ","IPR012340; IPR011129; IPR002059; ","\"Nucleic acid-binding, OB-fold; Cold shock domain; Cold-shock protein, DNA-binding; \"\r"]
["P17066","Heat shock 70 kDa protein 6 OS=Homo sapiens OX=9606 GN=HSPA6","HSPA6",71.027,4.0723,15.7,10,35,1,0.934,1.13,1.05,0.962,1.009,0.929,0.931,0.319,"cytoplasm\r","GO:0033554 cellular response to stress; GO:0045321 leukocyte activation; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0009628 response to abiotic stimulus; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0051234 establishment of localization; GO:0006457 protein folding; GO:0035966 response to topologically incorrect protein; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0009408 response to heat; GO:0009266 response to temperature stimulus; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0051716 cellular response to stimulus; GO:0006986 response to unfolded protein; GO:0002443 leukocyte mediated immunity; GO:0006950 response to stress; GO:0016192 vesicle-mediated transport; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0043312 neutrophil degranulation; GO:0002263 cell activation involved in immune response; GO:0002444 myeloid leukocyte mediated immunity; GO:0002366 leukocyte activation involved in immune response; GO:0006810 transport; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0042221 response to chemical; GO:0034605 cellular response to heat; GO:0032940 secretion by cell; GO:0001775 cell activation; GO:0043299 leukocyte degranulation; GO:0051179 localization; GO:0006955 immune response; GO:0042026 protein refolding; GO:0006887 exocytosis; ","GO:0034774 secretory granule lumen; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0044450 microtubule organizing center part; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0005815 microtubule organizing center; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0072562 blood microparticle; GO:0060205 cytoplasmic vesicle lumen; GO:0005813 centrosome; GO:0005814 centriole; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0016887 ATPase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0031072 heat shock protein binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0042623 ATPase activity, coupled; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0051082 unfolded protein binding; GO:0019899 enzyme binding; GO:0036094 small molecule binding; ","K03283","HSPA1s; heat shock 70kDa protein 1/2/6/8","hsa03040 Spliceosome - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); hsa05020 Prion diseases - Homo sapiens (human); hsa05162 Measles - Homo sapiens (human); hsa05134 Legionellosis - Homo sapiens (human); hsa04010 MAPK signaling pathway - Homo sapiens (human); hsa04144 Endocytosis - Homo sapiens (human); hsa04612 Antigen processing and presentation - Homo sapiens (human); hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); hsa04213 Longevity regulating pathway - multiple species - Homo sapiens (human); hsa04915 Estrogen signaling pathway - Homo sapiens (human); hsa05145 Toxoplasmosis - Homo sapiens (human); hsa05164 Influenza A - Homo sapiens (human); ","IPR029048; IPR029047; ","\"Heat shock protein 70kD, C-terminal domain; Heat shock protein 70kD, peptide-binding domain; \"\r"]
["P17174","Aspartate aminotransferase, cytoplasmic OS=Homo sapiens OX=9606 GN=GOT1","GOT1",46.247,84.303,26.6,9,15,9,1.042,0.975,1.021,1.057,1.012,1.006,1.012,0.651,"cytoplasm\r","GO:0044700 single organism signaling; GO:0019550 glutamate catabolic process to aspartate; GO:1901606 alpha-amino acid catabolic process; GO:0065008 regulation of biological quality; GO:0019319 hexose biosynthetic process; GO:0016053 organic acid biosynthetic process; GO:0007166 cell surface receptor signaling pathway; GO:0006066 alcohol metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0006006 glucose metabolic process; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0006094 gluconeogenesis; GO:0006520 cellular amino acid metabolic process; GO:1901653 cellular response to peptide; GO:0007154 cell communication; GO:0044262 cellular carbohydrate metabolic process; GO:1901607 alpha-amino acid biosynthetic process; GO:0048545 response to steroid hormone; GO:0009719 response to endogenous stimulus; GO:0006103 2-oxoglutarate metabolic process; GO:0034637 cellular carbohydrate biosynthetic process; GO:1901652 response to peptide; GO:0055088 lipid homeostasis; GO:0007219 Notch signaling pathway; GO:0070887 cellular response to chemical stimulus; GO:0006106 fumarate metabolic process; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0050801 ion homeostasis; GO:0019401 alditol biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006107 oxaloacetate metabolic process; GO:0055081 anion homeostasis; GO:1901617 organic hydroxy compound biosynthetic process; GO:0023052 signaling; GO:0005975 carbohydrate metabolic process; GO:0051384 response to glucocorticoid; GO:0071417 cellular response to organonitrogen compound; GO:0046395 carboxylic acid catabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0043650 dicarboxylic acid biosynthetic process; GO:1901575 organic substance catabolic process; GO:0010243 response to organonitrogen compound; GO:0009068 aspartate family amino acid catabolic process; GO:0046394 carboxylic acid biosynthetic process; GO:0032868 response to insulin; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0043434 response to peptide hormone; GO:1901699 cellular response to nitrogen compound; GO:0032870 cellular response to hormone stimulus; GO:0044710 single-organism metabolic process; GO:0009065 glutamine family amino acid catabolic process; GO:1901698 response to nitrogen compound; GO:0032869 cellular response to insulin stimulus; GO:0009063 cellular amino acid catabolic process; GO:0006082 organic acid metabolic process; GO:0043436 oxoacid metabolic process; GO:0050794 regulation of cellular process; GO:0043648 dicarboxylic acid metabolic process; GO:0006532 aspartate biosynthetic process; GO:0016051 carbohydrate biosynthetic process; GO:1901615 organic hydroxy compound metabolic process; GO:0071310 cellular response to organic substance; GO:1901700 response to oxygen-containing compound; GO:0009066 aspartate family amino acid metabolic process; GO:0006071 glycerol metabolic process; GO:0046364 monosaccharide biosynthetic process; GO:0006538 glutamate catabolic process; GO:0050896 response to stimulus; GO:1901566 organonitrogen compound biosynthetic process; GO:0006114 glycerol biosynthetic process; GO:0071704 organic substance metabolic process; GO:0033993 response to lipid; GO:0042592 homeostatic process; GO:0043649 dicarboxylic acid catabolic process; GO:0071375 cellular response to peptide hormone stimulus; GO:0031960 response to corticosteroid; GO:0005996 monosaccharide metabolic process; GO:0006536 glutamate metabolic process; GO:0044248 cellular catabolic process; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0009064 glutamine family amino acid metabolic process; GO:0019400 alditol metabolic process; GO:0009067 aspartate family amino acid biosynthetic process; GO:0008652 cellular amino acid biosynthetic process; GO:0044711 single-organism biosynthetic process; GO:0044712 single-organism catabolic process; GO:0055089 fatty acid homeostasis; GO:0006807 nitrogen compound metabolic process; GO:0046165 alcohol biosynthetic process; GO:0044282 small molecule catabolic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901605 alpha-amino acid metabolic process; GO:1901576 organic substance biosynthetic process; GO:0019751 polyol metabolic process; GO:0044249 cellular biosynthetic process; GO:0006531 aspartate metabolic process; GO:1901701 cellular response to oxygen-containing compound; GO:1901565 organonitrogen compound catabolic process; GO:0019551 glutamate catabolic process to 2-oxoglutarate; GO:0071495 cellular response to endogenous stimulus; GO:0006533 aspartate catabolic process; GO:0016054 organic acid catabolic process; GO:0019752 carboxylic acid metabolic process; GO:0044283 small molecule biosynthetic process; GO:0046173 polyol biosynthetic process; GO:0009725 response to hormone; GO:0009056 catabolic process; GO:0065007 biological regulation; GO:0019318 hexose metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043679 axon terminus; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0098793 presynapse; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0044306 neuron projection terminus; GO:0097458 neuron part; GO:0043233 organelle lumen; GO:0044456 synapse part; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0005576 extracellular region; GO:0045202 synapse; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005773 vacuole; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0016769 transferase activity, transferring nitrogenous groups; GO:0047801 L-cysteine:2-oxoglutarate aminotransferase activity; GO:0043167 ion binding; GO:0043177 organic acid binding; GO:0016829 lyase activity; GO:0048037 cofactor binding; GO:0030170 pyridoxal phosphate binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0031406 carboxylic acid binding; GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016830 carbon-carbon lyase activity; GO:0004609 phosphatidylserine decarboxylase activity; GO:0016831 carboxy-lyase activity; GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity; GO:0043168 anion binding; GO:0070546 L-phenylalanine aminotransferase activity; GO:0008483 transaminase activity; GO:0016740 transferase activity; GO:0036094 small molecule binding; ","K14454","GOT1; aspartate aminotransferase, cytoplasmic [EC:2.6.1.1]","hsa01210 2-Oxocarboxylic acid metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00270 Cysteine and methionine metabolism - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); hsa00330 Arginine and proline metabolism - Homo sapiens (human); hsa00220 Arginine biosynthesis - Homo sapiens (human); hsa00400 Phenylalanine, tyrosine and tryptophan biosynthesis - Homo sapiens (human); hsa00350 Tyrosine metabolism - Homo sapiens (human); hsa00360 Phenylalanine metabolism - Homo sapiens (human); hsa01230 Biosynthesis of amino acids - Homo sapiens (human); hsa00250 Alanine, aspartate and glutamate metabolism - Homo sapiens (human); ","IPR004839; IPR015424; IPR015421; ","\"Aminotransferase, class I/classII; Pyridoxal phosphate-dependent transferase; Pyridoxal phosphate-dependent transferase, major region, subdomain 1; \"\r"]
["P17213","Bactericidal permeability-increasing protein OS=Homo sapiens OX=9606 GN=BPI","BPI",53.899,6.258,2.3,1,3,1,0.726,0.769,0.711,1.17,1.195,1.4,1.707,0.000975,"extracellular\r","GO:0002694 regulation of leukocyte activation; GO:1903555 regulation of tumor necrosis factor superfamily cytokine production; GO:0045321 leukocyte activation; GO:0032715 negative regulation of interleukin-6 production; GO:0043030 regulation of macrophage activation; GO:0032680 regulation of tumor necrosis factor production; GO:0098542 defense response to other organism; GO:0044699 single-organism process; GO:0051241 negative regulation of multicellular organismal process; GO:0001818 negative regulation of cytokine production; GO:0051234 establishment of localization; GO:0009607 response to biotic stimulus; GO:0009605 response to external stimulus; GO:0002695 negative regulation of leukocyte activation; GO:0019731 antibacterial humoral response; GO:0070887 cellular response to chemical stimulus; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0050829 defense response to Gram-negative bacterium; GO:0019730 antimicrobial humoral response; GO:0002237 response to molecule of bacterial origin; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0002444 myeloid leukocyte mediated immunity; GO:0051704 multi-organism process; GO:0071396 cellular response to lipid; GO:0043031 negative regulation of macrophage activation; GO:0002683 negative regulation of immune system process; GO:0006810 transport; GO:0050865 regulation of cell activation; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032940 secretion by cell; GO:0002682 regulation of immune system process; GO:0043299 leukocyte degranulation; GO:0006952 defense response; GO:0050794 regulation of cellular process; GO:0032677 regulation of interleukin-8 production; GO:0002283 neutrophil activation involved in immune response; GO:0071222 cellular response to lipopolysaccharide; GO:0002252 immune effector process; GO:0071310 cellular response to organic substance; GO:1901700 response to oxygen-containing compound; GO:0006959 humoral immune response; GO:0048523 negative regulation of cellular process; GO:0043207 response to external biotic stimulus; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0051239 regulation of multicellular organismal process; GO:0050866 negative regulation of cell activation; GO:0033993 response to lipid; GO:0071216 cellular response to biotic stimulus; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:1903556 negative regulation of tumor necrosis factor superfamily cytokine production; GO:0036230 granulocyte activation; GO:0032717 negative regulation of interleukin-8 production; GO:0009987 cellular process; GO:0009617 response to bacterium; GO:0006950 response to stress; GO:0032496 response to lipopolysaccharide; GO:0042742 defense response to bacterium; GO:0032720 negative regulation of tumor necrosis factor production; GO:0016192 vesicle-mediated transport; GO:0032675 regulation of interleukin-6 production; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0043312 neutrophil degranulation; GO:0002263 cell activation involved in immune response; GO:0002366 leukocyte activation involved in immune response; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:1901701 cellular response to oxygen-containing compound; GO:0071219 cellular response to molecule of bacterial origin; GO:0001775 cell activation; GO:0001817 regulation of cytokine production; GO:0051179 localization; GO:0006955 immune response; GO:0006887 exocytosis; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0031224 intrinsic component of membrane; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:0044422 organelle part; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0005775 vacuolar lumen; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0010494 cytoplasmic stress granule; GO:0031226 intrinsic component of plasma membrane; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0042582 azurophil granule; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0060205 cytoplasmic vesicle lumen; GO:0035580 specific granule lumen; GO:0005766 primary lysosome; GO:0042581 specific granule; GO:0044437 vacuolar part; GO:0035770 ribonucleoprotein granule; GO:0005773 vacuole; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0008289 lipid binding; GO:0001530 lipopolysaccharide binding; GO:0097367 carbohydrate derivative binding; GO:0005488 binding; ",{"$nulls":3},"IPR017943; IPR001124; IPR017942; ","\"Bactericidal permeability-increasing protein, alpha/beta domain; Lipid-binding serum glycoprotein, C-terminal; Lipid-binding serum glycoprotein, N-terminal; \"\r"]
["P17301","Integrin alpha-2 OS=Homo sapiens OX=9606 GN=ITGA2","ITGA2",129.29,31.92,6.7,7,9,7,1.064,1.145,1.234,0.898,0.89,0.795,0.75,0.00778,"plasma membrane\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0044409 entry into host; GO:0051971 positive regulation of transmission of nerve impulse; GO:0060100 positive regulation of phagocytosis, engulfment; GO:0048732 gland development; GO:0022414 reproductive process; GO:0010608 posttranscriptional regulation of gene expression; GO:0009891 positive regulation of biosynthetic process; GO:0031347 regulation of defense response; GO:0044706 multi-multicellular organism process; GO:0044093 positive regulation of molecular function; GO:0007160 cell-matrix adhesion; GO:0034332 adherens junction organization; GO:0044057 regulation of system process; GO:0009790 embryo development; GO:0051099 positive regulation of binding; GO:0048598 embryonic morphogenesis; GO:0050906 detection of stimulus involved in sensory perception; GO:0046718 viral entry into host cell; GO:0051716 cellular response to stimulus; GO:0043588 skin development; GO:0071214 cellular response to abiotic stimulus; GO:0080090 regulation of primary metabolic process; GO:0050729 positive regulation of inflammatory response; GO:0044763 single-organism cellular process; GO:0038065 collagen-activated signaling pathway; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0048870 cell motility; GO:0071396 cellular response to lipid; GO:0051704 multi-organism process; GO:0010243 response to organonitrogen compound; GO:0014823 response to activity; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:1901698 response to nitrogen compound; GO:0002687 positive regulation of leukocyte migration; GO:0071392 cellular response to estradiol stimulus; GO:0030855 epithelial cell differentiation; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0000003 reproduction; GO:0043589 skin morphogenesis; GO:0044707 single-multicellular organism process; GO:0060099 regulation of phagocytosis, engulfment; GO:0051806 entry into cell of other organism involved in symbiotic interaction; GO:1901700 response to oxygen-containing compound; GO:0050926 regulation of positive chemotaxis; GO:0042493 response to drug; GO:0009653 anatomical structure morphogenesis; GO:0051345 positive regulation of hydrolase activity; GO:2000145 regulation of cell motility; GO:0009889 regulation of biosynthetic process; GO:0043062 extracellular structure organization; GO:0070482 response to oxygen levels; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0030100 regulation of endocytosis; GO:0045785 positive regulation of cell adhesion; GO:0006950 response to stress; GO:0051270 regulation of cellular component movement; GO:0009582 detection of abiotic stimulus; GO:0050766 positive regulation of phagocytosis; GO:0008283 cell proliferation; GO:0032101 regulation of response to external stimulus; GO:0010033 response to organic substance; GO:0007584 response to nutrient; GO:0014911 positive regulation of smooth muscle cell migration; GO:0034248 regulation of cellular amide metabolic process; GO:0001889 liver development; GO:0031325 positive regulation of cellular metabolic process; GO:0008284 positive regulation of cell proliferation; GO:0044246 regulation of multicellular organismal metabolic process; GO:0051674 localization of cell; GO:0040017 positive regulation of locomotion; GO:0033627 cell adhesion mediated by integrin; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:0045216 cell-cell junction organization; GO:0044699 single-organism process; GO:0033341 regulation of collagen binding; GO:0009611 response to wounding; GO:0014075 response to amine; GO:0048729 tissue morphogenesis; GO:0007165 signal transduction; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0031644 regulation of neurological system process; GO:0007045 cell-substrate adherens junction assembly; GO:0030198 extracellular matrix organization; GO:0033036 macromolecule localization; GO:0033273 response to vitamin; GO:0007044 cell-substrate junction assembly; GO:0045937 positive regulation of phosphate metabolic process; GO:0006970 response to osmotic stress; GO:0031326 regulation of cellular biosynthetic process; GO:0051098 regulation of binding; GO:0090257 regulation of muscle system process; GO:0007229 integrin-mediated signaling pathway; GO:0023052 signaling; GO:0051969 regulation of transmission of nerve impulse; GO:0070365 hepatocyte differentiation; GO:0065009 regulation of molecular function; GO:0016477 cell migration; GO:0016043 cellular component organization; GO:0071260 cellular response to mechanical stimulus; GO:0032967 positive regulation of collagen biosynthetic process; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0019058 viral life cycle; GO:0051101 regulation of DNA binding; GO:0007369 gastrulation; GO:0033993 response to lipid; GO:0009612 response to mechanical stimulus; GO:0030154 cell differentiation; GO:0023056 positive regulation of signaling; GO:0016032 viral process; GO:0001666 response to hypoxia; GO:1905155 positive regulation of membrane invagination; GO:0010647 positive regulation of cell communication; GO:0050974 detection of mechanical stimulus involved in sensory perception; GO:0050878 regulation of body fluid levels; GO:0010921 regulation of phosphatase activity; GO:0051049 regulation of transport; GO:0006937 regulation of muscle contraction; GO:0010634 positive regulation of epithelial cell migration; GO:0050920 regulation of chemotaxis; GO:0043085 positive regulation of catalytic activity; GO:0071107 response to parathyroid hormone; GO:1901701 cellular response to oxygen-containing compound; GO:0048332 mesoderm morphogenesis; GO:0044703 multi-organism reproductive process; GO:0002684 positive regulation of immune system process; GO:0050727 regulation of inflammatory response; GO:0014910 regulation of smooth muscle cell migration; GO:0071840 cellular component organization or biogenesis; GO:0060627 regulation of vesicle-mediated transport; GO:0065008 regulation of biological quality; GO:0007596 blood coagulation; GO:0030335 positive regulation of cell migration; GO:0032270 positive regulation of cellular protein metabolic process; GO:0007166 cell surface receptor signaling pathway; GO:0045933 positive regulation of muscle contraction; GO:0006971 hypotonic response; GO:0050877 neurological system process; GO:0022610 biological adhesion; GO:0009605 response to external stimulus; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0051606 detection of stimulus; GO:0007155 cell adhesion; GO:0009719 response to endogenous stimulus; GO:0010562 positive regulation of phosphorus metabolic process; GO:0050921 positive regulation of chemotaxis; GO:0009743 response to carbohydrate; GO:0008104 protein localization; GO:0044419 interspecies interaction between organisms; GO:0014070 response to organic cyclic compound; GO:0051174 regulation of phosphorus metabolic process; GO:0010632 regulation of epithelial cell migration; GO:0031346 positive regulation of cell projection organization; GO:0001707 mesoderm formation; GO:0051272 positive regulation of cellular component movement; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0048041 focal adhesion assembly; GO:0043388 positive regulation of DNA binding; GO:0007498 mesoderm development; GO:0048513 animal organ development; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0034284 response to monosaccharide; GO:0010604 positive regulation of macromolecule metabolic process; GO:0009887 animal organ morphogenesis; GO:0002682 regulation of immune system process; GO:0050817 coagulation; GO:0002685 regulation of leukocyte migration; GO:0050982 detection of mechanical stimulus; GO:0050794 regulation of cellular process; GO:0042127 regulation of cell proliferation; GO:0009581 detection of external stimulus; GO:0009628 response to abiotic stimulus; GO:0014850 response to muscle activity; GO:0032355 response to estradiol; GO:0080134 regulation of response to stress; GO:2000147 positive regulation of cell motility; GO:0051239 regulation of multicellular organismal process; GO:0030879 mammary gland development; GO:0033591 response to L-ascorbic acid; GO:0010922 positive regulation of phosphatase activity; GO:0007565 female pregnancy; GO:0010692 regulation of alkaline phosphatase activity; GO:0031349 positive regulation of defense response; GO:0010628 positive regulation of gene expression; GO:0051171 regulation of nitrogen compound metabolic process; GO:0061008 hepaticobiliary system development; GO:0044253 positive regulation of multicellular organismal metabolic process; GO:0007275 multicellular organism development; GO:0048731 system development; GO:0050927 positive regulation of positive chemotaxis; GO:0030334 regulation of cell migration; GO:0071407 cellular response to organic cyclic compound; GO:0071496 cellular response to external stimulus; GO:0030155 regulation of cell adhesion; GO:0045184 establishment of protein localization; GO:0032965 regulation of collagen biosynthetic process; GO:0051247 positive regulation of protein metabolic process; GO:0006928 movement of cell or subcellular component; GO:0048661 positive regulation of smooth muscle cell proliferation; GO:0010694 positive regulation of alkaline phosphatase activity; GO:0036293 response to decreased oxygen levels; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:0031328 positive regulation of cellular biosynthetic process; GO:0010712 regulation of collagen metabolic process; GO:0001101 response to acid chemical; GO:0032092 positive regulation of protein binding; GO:0044764 multi-organism cellular process; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0032103 positive regulation of response to external stimulus; GO:0035303 regulation of dephosphorylation; GO:0006929 substrate-dependent cell migration; GO:0050764 regulation of phagocytosis; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0060429 epithelium development; GO:0007600 sensory perception; GO:0009888 tissue development; GO:0045727 positive regulation of translation; GO:1905153 regulation of membrane invagination; GO:0001704 formation of primary germ layer; GO:0048522 positive regulation of cellular process; GO:0051050 positive regulation of transport; GO:0030260 entry into host cell; GO:0032268 regulation of cellular protein metabolic process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0035306 positive regulation of dephosphorylation; GO:0010714 positive regulation of collagen metabolic process; GO:0051828 entry into other organism involved in symbiotic interaction; GO:0006940 regulation of smooth muscle contraction; GO:0019222 regulation of metabolic process; GO:0034333 adherens junction assembly; GO:0019220 regulation of phosphate metabolic process; GO:0040011 locomotion; GO:0050966 detection of mechanical stimulus involved in sensory perception of pain; GO:0048856 anatomical structure development; GO:0050954 sensory perception of mechanical stimulus; GO:0034329 cell junction assembly; GO:0033343 positive regulation of collagen binding; GO:0048660 regulation of smooth muscle cell proliferation; GO:0045807 positive regulation of endocytosis; GO:0031344 regulation of cell projection organization; GO:0050896 response to stimulus; GO:0019233 sensory perception of pain; GO:0007599 hemostasis; GO:0043393 regulation of protein binding; GO:0009991 response to extracellular stimulus; GO:0045987 positive regulation of smooth muscle contraction; GO:0009987 cellular process; GO:0003008 system process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0051701 interaction with host; GO:0048518 positive regulation of biological process; GO:0048333 mesodermal cell differentiation; GO:0031646 positive regulation of neurological system process; GO:0042060 wound healing; GO:0034330 cell junction organization; GO:0031589 cell-substrate adhesion; GO:0006417 regulation of translation; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0034250 positive regulation of cellular amide metabolic process; GO:0051128 regulation of cellular component organization; GO:0031667 response to nutrient levels; GO:0009725 response to hormone; GO:0040012 regulation of locomotion; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0098636 protein complex involved in cell adhesion; GO:0009897 external side of plasma membrane; GO:0098796 membrane protein complex; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0043679 axon terminus; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0098793 presynapse; GO:0044464 cell part; GO:0044425 membrane part; GO:0005912 adherens junction; GO:0048471 perinuclear region of cytoplasm; GO:0043005 neuron projection; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0044306 neuron projection terminus; GO:0097458 neuron part; GO:0044456 synapse part; GO:0005924 cell-substrate adherens junction; GO:0098552 side of membrane; GO:0043229 intracellular organelle; GO:0031226 intrinsic component of plasma membrane; GO:0042995 cell projection; GO:0098797 plasma membrane protein complex; GO:0098802 plasma membrane receptor complex; GO:0043235 receptor complex; GO:0070161 anchoring junction; GO:0034666 integrin alpha2-beta1 complex; GO:0008305 integrin complex; GO:0044463 cell projection part; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0045202 synapse; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0030424 axon; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0009986 cell surface; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0045178 basal part of cell; ","GO:0038023 signaling receptor activity; GO:0098639 collagen binding involved in cell-matrix adhesion; GO:0046982 protein heterodimerization activity; GO:0005102 receptor binding; GO:0043167 ion binding; GO:0046983 protein dimerization activity; GO:0044877 macromolecular complex binding; GO:0005515 protein binding; GO:0005178 integrin binding; GO:0004888 transmembrane signaling receptor activity; GO:0004871 signal transducer activity; GO:0050840 extracellular matrix binding; GO:0001618 virus receptor activity; GO:0050839 cell adhesion molecule binding; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0098631 protein binding involved in cell adhesion; GO:0043236 laminin binding; GO:0005488 binding; GO:0038064 collagen receptor activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005518 collagen binding; GO:0098634 protein binding involved in cell-matrix adhesion; GO:0032403 protein complex binding; GO:0099600 transmembrane receptor activity; ","K06481","ITGA2; integrin alpha 2","hsa05200 Pathways in cancer - Homo sapiens (human); hsa05414 Dilated cardiomyopathy (DCM) - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa04640 Hematopoietic cell lineage - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa05222 Small cell lung cancer - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa04611 Platelet activation - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa04512 ECM-receptor interaction - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); hsa05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human); hsa05410 Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human); ","IPR032695; IPR013649; IPR002035; ","\"Integrin domain; Integrin alpha-2; von Willebrand factor, type A; \"\r"]
["P17302","Gap junction alpha-1 protein OS=Homo sapiens OX=9606 GN=GJA1","GJA1",43.008,17.397,7.9,2,3,2,1.025,0.846,1.069,1.073,0.959,1.032,1.042,0.598,"plasma membrane\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0022414 reproductive process; GO:0050796 regulation of insulin secretion; GO:1901862 negative regulation of muscle tissue development; GO:0002793 positive regulation of peptide secretion; GO:0031347 regulation of defense response; GO:0051503 adenine nucleotide transport; GO:0009607 response to biotic stimulus; GO:0001558 regulation of cell growth; GO:0061337 cardiac conduction; GO:0045843 negative regulation of striated muscle tissue development; GO:0065003 macromolecular complex assembly; GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling; GO:0044706 multi-multicellular organism process; GO:0055065 metal ion homeostasis; GO:0044057 regulation of system process; GO:0002544 chronic inflammatory response; GO:0051716 cellular response to stimulus; GO:0019229 regulation of vasoconstriction; GO:0071214 cellular response to abiotic stimulus; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0006862 nucleotide transport; GO:0044763 single-organism cellular process; GO:0016264 gap junction assembly; GO:0006874 cellular calcium ion homeostasis; GO:0035296 regulation of tube diameter; GO:0051704 multi-organism process; GO:0006810 transport; GO:0010243 response to organonitrogen compound; GO:0007267 cell-cell signaling; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0051223 regulation of protein transport; GO:0086014 atrial cardiac muscle cell action potential; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0048609 multicellular organismal reproductive process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0000003 reproduction; GO:0072359 circulatory system development; GO:0044707 single-multicellular organism process; GO:0060135 maternal process involved in female pregnancy; GO:0034220 ion transmembrane transport; GO:0050880 regulation of blood vessel size; GO:0086066 atrial cardiac muscle cell to AV node cell communication; GO:1901700 response to oxygen-containing compound; GO:0003018 vascular process in circulatory system; GO:0048519 negative regulation of biological process; GO:0090277 positive regulation of peptide hormone secretion; GO:0009653 anatomical structure morphogenesis; GO:0086003 cardiac muscle cell contraction; GO:0009889 regulation of biosynthetic process; GO:0009896 positive regulation of catabolic process; GO:1901264 carbohydrate derivative transport; GO:0010959 regulation of metal ion transport; GO:0042176 regulation of protein catabolic process; GO:0001936 regulation of endothelial cell proliferation; GO:0035150 regulation of tube size; GO:0061458 reproductive system development; GO:0048878 chemical homeostasis; GO:0006950 response to stress; GO:0032496 response to lipopolysaccharide; GO:0003014 renal system process; GO:0051924 regulation of calcium ion transport; GO:0032101 regulation of response to external stimulus; GO:0010033 response to organic substance; GO:2000278 regulation of DNA biosynthetic process; GO:0009890 negative regulation of biosynthetic process; GO:0061041 regulation of wound healing; GO:1903034 regulation of response to wounding; GO:0003071 renal system process involved in regulation of systemic arterial blood pressure; GO:0030048 actin filament-based movement; GO:0051093 negative regulation of developmental process; GO:0003012 muscle system process; GO:0009746 response to hexose; GO:0060420 regulation of heart growth; GO:0023051 regulation of signaling; GO:0048634 regulation of muscle organ development; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0045216 cell-cell junction organization; GO:0051046 regulation of secretion; GO:0044699 single-organism process; GO:0001893 maternal placenta development; GO:0097746 regulation of blood vessel diameter; GO:0007165 signal transduction; GO:0009893 positive regulation of metabolic process; GO:0032990 cell part morphogenesis; GO:0006915 apoptotic process; GO:0048858 cell projection morphogenesis; GO:0055024 regulation of cardiac muscle tissue development; GO:0045926 negative regulation of growth; GO:1903367 positive regulation of fear response; GO:0031326 regulation of cellular biosynthetic process; GO:0002237 response to molecule of bacterial origin; GO:0098771 inorganic ion homeostasis; GO:0035637 multicellular organismal signaling; GO:0048608 reproductive structure development; GO:1903530 regulation of secretion by cell; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:1903035 negative regulation of response to wounding; GO:0016202 regulation of striated muscle tissue development; GO:0003104 positive regulation of glomerular filtration; GO:0061117 negative regulation of heart growth; GO:0051052 regulation of DNA metabolic process; GO:0006954 inflammatory response; GO:0006952 defense response; GO:0070271 protein complex biogenesis; GO:0051222 positive regulation of protein transport; GO:0060044 negative regulation of cardiac muscle cell proliferation; GO:0016043 cellular component organization; GO:0071260 cellular response to mechanical stimulus; GO:0010232 vascular transport; GO:0040008 regulation of growth; GO:0010645 regulation of cell communication by chemical coupling; GO:0060255 regulation of macromolecule metabolic process; GO:1903522 regulation of blood circulation; GO:0060048 cardiac muscle contraction; GO:0048638 regulation of developmental growth; GO:0051707 response to other organism; GO:0042592 homeostatic process; GO:0009612 response to mechanical stimulus; GO:0033993 response to lipid; GO:0009268 response to pH; GO:0030154 cell differentiation; GO:0010652 positive regulation of cell communication by chemical coupling; GO:0055080 cation homeostasis; GO:0023056 positive regulation of signaling; GO:0008015 blood circulation; GO:0010647 positive regulation of cell communication; GO:0034405 response to fluid shear stress; GO:0032024 positive regulation of insulin secretion; GO:0050878 regulation of body fluid levels; GO:0051049 regulation of transport; GO:0015865 purine nucleotide transport; GO:0045907 positive regulation of vasoconstriction; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0008219 cell death; GO:0044703 multi-organism reproductive process; GO:2000822 regulation of behavioral fear response; GO:0031327 negative regulation of cellular biosynthetic process; GO:0086065 cell communication involved in cardiac conduction; GO:0071840 cellular component organization or biogenesis; GO:0065008 regulation of biological quality; GO:0032989 cellular component morphogenesis; GO:0015868 purine ribonucleotide transport; GO:0009749 response to glucose; GO:0008285 negative regulation of cell proliferation; GO:2000987 positive regulation of behavioral fear response; GO:0046697 decidualization; GO:0009605 response to external stimulus; GO:0007507 heart development; GO:0051240 positive regulation of multicellular organismal process; GO:0050678 regulation of epithelial cell proliferation; GO:0015931 nucleobase-containing compound transport; GO:0032879 regulation of localization; GO:0032102 negative regulation of response to external stimulus; GO:0044702 single organism reproductive process; GO:2000279 negative regulation of DNA biosynthetic process; GO:0009719 response to endogenous stimulus; GO:0009743 response to carbohydrate; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:1901652 response to peptide; GO:0044765 single-organism transport; GO:0007399 nervous system development; GO:0003006 developmental process involved in reproduction; GO:2000810 regulation of bicellular tight junction assembly; GO:0009894 regulation of catabolic process; GO:0043269 regulation of ion transport; GO:0006941 striated muscle contraction; GO:0048812 neuron projection morphogenesis; GO:0031323 regulation of cellular metabolic process; GO:1901888 regulation of cell junction assembly; GO:0032501 multicellular organismal process; GO:0015858 nucleoside transport; GO:0000902 cell morphogenesis; GO:0048635 negative regulation of muscle organ development; GO:0048513 animal organ development; GO:0046883 regulation of hormone secretion; GO:0051053 negative regulation of DNA metabolic process; GO:0032526 response to retinoic acid; GO:0034284 response to monosaccharide; GO:0050714 positive regulation of protein secretion; GO:0010604 positive regulation of macromolecule metabolic process; GO:0010817 regulation of hormone levels; GO:0003015 heart process; GO:0003013 circulatory system process; GO:0051047 positive regulation of secretion; GO:0050794 regulation of cellular process; GO:0050795 regulation of behavior; GO:0042127 regulation of cell proliferation; GO:0001890 placenta development; GO:0048520 positive regulation of behavior; GO:0009628 response to abiotic stimulus; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0055022 negative regulation of cardiac muscle tissue growth; GO:0051239 regulation of multicellular organismal process; GO:0051259 protein oligomerization; GO:0007565 female pregnancy; GO:0031349 positive regulation of defense response; GO:1902578 single-organism localization; GO:0051171 regulation of nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0032880 regulation of protein localization; GO:0009966 regulation of signal transduction; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0009617 response to bacterium; GO:0006461 protein complex assembly; GO:0090087 regulation of peptide transport; GO:0010644 cell communication by electrical coupling; GO:1902531 regulation of intracellular signal transduction; GO:0048731 system development; GO:0071496 cellular response to external stimulus; GO:0071702 organic substance transport; GO:0086064 cell communication by electrical coupling involved in cardiac conduction; GO:0046621 negative regulation of organ growth; GO:0009892 negative regulation of metabolic process; GO:0003158 endothelium development; GO:0060043 regulation of cardiac muscle cell proliferation; GO:0030182 neuron differentiation; GO:0055085 transmembrane transport; GO:0051247 positive regulation of protein metabolic process; GO:1904951 positive regulation of establishment of protein localization; GO:0006873 cellular ion homeostasis; GO:0006811 ion transport; GO:0030029 actin filament-based process; GO:0046887 positive regulation of hormone secretion; GO:0006928 movement of cell or subcellular component; GO:0012501 programmed cell death; GO:0007204 positive regulation of cytosolic calcium ion concentration; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0046620 regulation of organ growth; GO:0055021 regulation of cardiac muscle tissue growth; GO:0001101 response to acid chemical; GO:0070252 actin-mediated cell contraction; GO:0072503 cellular divalent inorganic cation homeostasis; GO:0048640 negative regulation of developmental growth; GO:1902533 positive regulation of intracellular signal transduction; GO:0022008 neurogenesis; GO:0051241 negative regulation of multicellular organismal process; GO:0051234 establishment of localization; GO:0002931 response to ischemia; GO:0001937 negative regulation of endothelial cell proliferation; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0003073 regulation of systemic arterial blood pressure; GO:0001508 action potential; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0086026 atrial cardiac muscle cell to AV node cell signaling; GO:0009888 tissue development; GO:0098801 regulation of renal system process; GO:0071822 protein complex subunit organization; GO:0050801 ion homeostasis; GO:0003093 regulation of glomerular filtration; GO:0055074 calcium ion homeostasis; GO:0019725 cellular homeostasis; GO:0048522 positive regulation of cellular process; GO:0051050 positive regulation of transport; GO:0042391 regulation of membrane potential; GO:0030308 negative regulation of cell growth; GO:0015748 organophosphate ester transport; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0086001 cardiac muscle cell action potential; GO:0043434 response to peptide hormone; GO:1903532 positive regulation of secretion by cell; GO:0030030 cell projection organization; GO:0019222 regulation of metabolic process; GO:0050680 negative regulation of epithelial cell proliferation; GO:0072507 divalent inorganic cation homeostasis; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0008217 regulation of blood pressure; GO:0034329 cell junction assembly; GO:0015867 ATP transport; GO:1903365 regulation of fear response; GO:0030003 cellular cation homeostasis; GO:0051480 regulation of cytosolic calcium ion concentration; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044087 regulation of cellular component biogenesis; GO:0043207 response to external biotic stimulus; GO:0031324 negative regulation of cellular metabolic process; GO:0008016 regulation of heart contraction; GO:0050896 response to stimulus; GO:0055082 cellular chemical homeostasis; GO:0048468 cell development; GO:0070201 regulation of establishment of protein localization; GO:0001977 renal system process involved in regulation of blood volume; GO:0002791 regulation of peptide secretion; GO:0006936 muscle contraction; GO:1903524 positive regulation of blood circulation; GO:0060047 heart contraction; GO:0050708 regulation of protein secretion; GO:0009987 cellular process; GO:0055026 negative regulation of cardiac muscle tissue development; GO:0007043 cell-cell junction assembly; GO:0003008 system process; GO:1901861 regulation of muscle tissue development; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0031175 neuron projection development; GO:0061045 negative regulation of wound healing; GO:0048518 positive regulation of biological process; GO:0086019 cell-cell signaling involved in cardiac conduction; GO:0032504 multicellular organism reproduction; GO:0006820 anion transport; GO:0015711 organic anion transport; GO:0034330 cell junction organization; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0086002 cardiac muscle cell action potential involved in contraction; GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling; GO:0090276 regulation of peptide hormone secretion; GO:0090066 regulation of anatomical structure size; GO:0006875 cellular metal ion homeostasis; GO:0045732 positive regulation of protein catabolic process; GO:0009967 positive regulation of signal transduction; GO:0051128 regulation of cellular component organization; GO:0009725 response to hormone; GO:0071705 nitrogen compound transport; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0019867 outer membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0098857 membrane microdomain; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0005913 cell-cell adherens junction; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0014704 intercalated disc; GO:0005769 early endosome; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0005764 lysosome; GO:0098589 membrane region; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005771 multivesicular body; GO:0005789 endoplasmic reticulum membrane; GO:0005924 cell-substrate adherens junction; GO:0000323 lytic vacuole; GO:0031226 intrinsic component of plasma membrane; GO:0005770 late endosome; GO:0031967 organelle envelope; GO:0098797 plasma membrane protein complex; GO:0070161 anchoring junction; GO:0005798 Golgi-associated vesicle; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0031975 envelope; GO:0005773 vacuole; GO:0043234 protein complex; GO:0031966 mitochondrial membrane; GO:0043230 extracellular organelle; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0044291 cell-cell contact zone; GO:0030054 cell junction; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0030660 Golgi-associated vesicle membrane; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005911 cell-cell junction; GO:0005740 mitochondrial envelope; GO:0005922 connexin complex; GO:0044425 membrane part; GO:0044464 cell part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0005912 adherens junction; GO:0044431 Golgi apparatus part; GO:0031968 organelle outer membrane; GO:0005916 fascia adherens; GO:0005768 endosome; GO:0045121 membrane raft; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0005921 gap junction; GO:0044429 mitochondrial part; GO:0098588 bounding membrane of organelle; GO:0005741 mitochondrial outer membrane; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0016021 integral component of membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0044432 endoplasmic reticulum part; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:0005243 gap junction channel activity; GO:0015075 ion transmembrane transporter activity; GO:0022803 passive transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0030165 PDZ domain binding; GO:0017124 SH3 domain binding; GO:0004871 signal transducer activity; GO:0015267 channel activity; GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling; GO:0022891 substrate-specific transmembrane transporter activity; GO:0022829 wide pore channel activity; GO:0005488 binding; GO:0071253 connexin binding; GO:0019904 protein domain specific binding; GO:1903763 gap junction channel activity involved in cell communication by electrical coupling; GO:0022857 transmembrane transporter activity; GO:0005215 transporter activity; ","K07372","GJA1; gap junction alpha-1 protein","hsa04540 Gap junction - Homo sapiens (human); hsa05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human); ","IPR013124; IPR013092; IPR019570; ","\"Gap junction alpha-1 protein (Cx43), C-terminal; Connexin, N-terminal; Gap junction protein, cysteine-rich domain; \"\r"]
["P17405","Sphingomyelin phosphodiesterase OS=Homo sapiens OX=9606 GN=SMPD1","SMPD1",69.751,13.108,2.1,1,1,1,0.896,1.02,0.985,0.985,1.092,1.025,1.069,0.24,"plasma membrane\r","GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0032270 positive regulation of cellular protein metabolic process; GO:0006672 ceramide metabolic process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0008610 lipid biosynthetic process; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0008152 metabolic process; GO:0030148 sphingolipid biosynthetic process; GO:0009719 response to endogenous stimulus; GO:0010562 positive regulation of phosphorus metabolic process; GO:0007399 nervous system development; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0060359 response to ammonium ion; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0031323 regulation of cellular metabolic process; GO:0043086 negative regulation of catalytic activity; GO:0032501 multicellular organismal process; GO:1901575 organic substance catabolic process; GO:0010243 response to organonitrogen compound; GO:1902532 negative regulation of intracellular signal transduction; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0035304 regulation of protein dephosphorylation; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0010604 positive regulation of macromolecule metabolic process; GO:0042220 response to cocaine; GO:0043068 positive regulation of programmed cell death; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0043407 negative regulation of MAP kinase activity; GO:0031399 regulation of protein modification process; GO:1901700 response to oxygen-containing compound; GO:0043067 regulation of programmed cell death; GO:0043279 response to alkaloid; GO:0097164 ammonium ion metabolic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0042493 response to drug; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0051338 regulation of transferase activity; GO:1901135 carbohydrate derivative metabolic process; GO:0044248 cellular catabolic process; GO:0001933 negative regulation of protein phosphorylation; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:0016042 lipid catabolic process; GO:1902531 regulation of intracellular signal transduction; GO:0044711 single-organism biosynthetic process; GO:0048731 system development; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0006684 sphingomyelin metabolic process; GO:0051247 positive regulation of protein metabolic process; GO:0006793 phosphorus metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0043409 negative regulation of MAPK cascade; GO:0019637 organophosphate metabolic process; GO:0044242 cellular lipid catabolic process; GO:0006644 phospholipid metabolic process; GO:0045936 negative regulation of phosphate metabolic process; GO:0046513 ceramide biosynthetic process; GO:1901564 organonitrogen compound metabolic process; GO:0009968 negative regulation of signal transduction; GO:0006643 membrane lipid metabolic process; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0006796 phosphate-containing compound metabolic process; GO:0031400 negative regulation of protein modification process; GO:0009395 phospholipid catabolic process; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0071901 negative regulation of protein serine/threonine kinase activity; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0033673 negative regulation of kinase activity; GO:0035303 regulation of dephosphorylation; GO:0006665 sphingolipid metabolic process; GO:0006629 lipid metabolic process; GO:0032502 developmental process; GO:0046466 membrane lipid catabolic process; GO:0045937 positive regulation of phosphate metabolic process; GO:0006664 glycolipid metabolic process; GO:0048522 positive regulation of cellular process; GO:0023021 termination of signal transduction; GO:0043603 cellular amide metabolic process; GO:0051348 negative regulation of transferase activity; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0010942 positive regulation of cell death; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0035306 positive regulation of dephosphorylation; GO:0006469 negative regulation of protein kinase activity; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0048856 anatomical structure development; GO:0043549 regulation of kinase activity; GO:0045859 regulation of protein kinase activity; GO:0006685 sphingomyelin catabolic process; GO:1903509 liposaccharide metabolic process; GO:0046434 organophosphate catabolic process; GO:0043405 regulation of MAP kinase activity; GO:0060255 regulation of macromolecule metabolic process; GO:0006687 glycosphingolipid metabolic process; GO:0043065 positive regulation of apoptotic process; GO:0031324 negative regulation of cellular metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0030149 sphingolipid catabolic process; GO:0043408 regulation of MAPK cascade; GO:0042326 negative regulation of phosphorylation; GO:0034641 cellular nitrogen compound metabolic process; GO:0009987 cellular process; GO:0046467 membrane lipid biosynthetic process; GO:0035307 positive regulation of protein dephosphorylation; GO:0044712 single-organism catabolic process; GO:0001932 regulation of protein phosphorylation; GO:0006807 nitrogen compound metabolic process; GO:0031401 positive regulation of protein modification process; GO:0048585 negative regulation of response to stimulus; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:1901565 organonitrogen compound catabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0010563 negative regulation of phosphorus metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0043604 amide biosynthetic process; GO:0009056 catabolic process; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0042599 lamellar body; GO:0005623 cell; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0043202 lysosomal lumen; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0043167 ion binding; GO:0005515 protein binding; GO:0061750 acid sphingomyelin phosphodiesterase activity; GO:0016787 hydrolase activity; GO:0008270 zinc ion binding; GO:0016298 lipase activity; GO:0046914 transition metal ion binding; GO:0042578 phosphoric ester hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016798 hydrolase activity, acting on glycosyl bonds; GO:0016788 hydrolase activity, acting on ester bonds; GO:0004620 phospholipase activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0008081 phosphoric diester hydrolase activity; GO:0004767 sphingomyelin phosphodiesterase activity; ","K12350","SMPD1; sphingomyelin phosphodiesterase [EC:3.1.4.12]","hsa04142 Lysosome - Homo sapiens (human); hsa04071 Sphingolipid signaling pathway - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00600 Sphingolipid metabolism - Homo sapiens (human); hsa04217 Necroptosis - Homo sapiens (human); ","IPR029052; IPR008139; IPR004843; IPR011001; ","\"Metallo-dependent phosphatase-like; Saposin B type domain; Calcineurin-like phosphoesterase domain, ApaH type; Saposin-like; \"\r"]
["P17480","Nucleolar transcription factor 1 OS=Homo sapiens OX=9606 GN=UBTF","UBTF",89.405,6.9661,7.1,5,5,5,1.013,1.117,0.977,1.041,0.898,0.973,0.937,0.329,"nucleus\r","GO:0006361 transcription initiation from RNA polymerase I promoter; GO:0006360 transcription from RNA polymerase I promoter; GO:0097659 nucleic acid-templated transcription; GO:0009891 positive regulation of biosynthetic process; GO:0009058 biosynthetic process; GO:0006354 DNA-templated transcription, elongation; GO:0044237 cellular metabolic process; GO:0006353 DNA-templated transcription, termination; GO:0006363 termination of RNA polymerase I transcription; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0006356 regulation of transcription from RNA polymerase I promoter; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0006352 DNA-templated transcription, initiation; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0006362 transcription elongation from RNA polymerase I promoter; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0051254 positive regulation of RNA metabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:1901576 organic substance biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0031325 positive regulation of cellular metabolic process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0010467 gene expression; GO:0031328 positive regulation of cellular biosynthetic process; GO:0045943 positive regulation of transcription from RNA polymerase I promoter; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044452 nucleolar part; GO:0044424 intracellular part; GO:0005730 nucleolus; GO:0005623 cell; GO:0001650 fibrillar center; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0003677 DNA binding; GO:0003723 RNA binding; GO:0000976 transcription regulatory region sequence-specific DNA binding; GO:0003690 double-stranded DNA binding; GO:1990837 sequence-specific double-stranded DNA binding; GO:0001164 RNA polymerase I CORE element sequence-specific DNA binding; GO:0005515 protein binding; GO:0003682 chromatin binding; GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding; GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding; GO:0043565 sequence-specific DNA binding; GO:0000987 core promoter proximal region sequence-specific DNA binding; GO:0001047 core promoter binding; GO:0001159 core promoter proximal region DNA binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0000975 regulatory region DNA binding; GO:0001046 core promoter sequence-specific DNA binding; GO:0001067 regulatory region nucleic acid binding; GO:0001013 RNA polymerase I regulatory region DNA binding; GO:0005488 binding; GO:0044212 transcription regulatory region DNA binding; GO:0003676 nucleic acid binding; ","K09273",null,null,"IPR009071; IPR029215; ","High mobility group box domain; High mobility group box domain 5; \r"]
["P17540","Creatine kinase S-type, mitochondrial OS=Homo sapiens OX=9606 GN=CKMT2","CKMT2",47.504,17.367,18.9,6,7,4,0.897,1.013,1.023,1.047,0.977,1.048,1.047,0.38,"mitochondria\r","GO:0016310 phosphorylation; GO:0003012 muscle system process; GO:0003008 system process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:0044699 single-organism process; GO:0006600 creatine metabolic process; GO:1901605 alpha-amino acid metabolic process; GO:0044238 primary metabolic process; GO:0032501 multicellular organismal process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0006936 muscle contraction; GO:0006575 cellular modified amino acid metabolic process; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0006082 organic acid metabolic process; GO:0009987 cellular process; GO:0043436 oxoacid metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044429 mitochondrial part; GO:0031090 organelle membrane; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0005740 mitochondrial envelope; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0031975 envelope; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0004111 creatine kinase activity; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016775 phosphotransferase activity, nitrogenous group as acceptor; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016301 kinase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0016740 transferase activity; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K00933","E2.7.3.2; creatine kinase [EC:2.7.3.2]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00330 Arginine and proline metabolism - Homo sapiens (human); ","IPR022413; IPR014746; IPR022414; ","\"ATP:guanido phosphotransferase, N-terminal; Glutamine synthetase/guanido kinase, catalytic domain; ATP:guanido phosphotransferase, catalytic domain; \"\r"]
["P17568","NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 OS=Homo sapiens OX=9606 GN=NDUFB7","NDUFB7",16.402,8.5167,27.7,4,7,4,1.008,0.955,1.132,1.024,1.019,0.872,0.942,0.455,"extracellular\r","GO:0044085 cellular component biogenesis; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0022607 cellular component assembly; GO:0006753 nucleoside phosphate metabolic process; GO:0065003 macromolecular complex assembly; GO:0007005 mitochondrion organization; GO:0019693 ribose phosphate metabolic process; GO:0071822 protein complex subunit organization; GO:0010257 NADH dehydrogenase complex assembly; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0006119 oxidative phosphorylation; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0006120 mitochondrial electron transport, NADH to ubiquinone; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0097031 mitochondrial respiratory chain complex I biogenesis; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0022900 electron transport chain; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0070271 protein complex biogenesis; GO:0033108 mitochondrial respiratory chain complex assembly; GO:0016043 cellular component organization; GO:0016310 phosphorylation; GO:0006725 cellular aromatic compound metabolic process; GO:0042773 ATP synthesis coupled electron transport; GO:0009259 ribonucleotide metabolic process; GO:0022904 respiratory electron transport chain; GO:0071704 organic substance metabolic process; GO:0032981 mitochondrial respiratory chain complex I assembly; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0009119 ribonucleoside metabolic process; GO:0006461 protein complex assembly; GO:0043623 cellular protein complex assembly; GO:0046034 ATP metabolic process; GO:0034622 cellular macromolecular complex assembly; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0045333 cellular respiration; GO:0006163 purine nucleotide metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0046128 purine ribonucleoside metabolic process; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:1901564 organonitrogen compound metabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0045271 respiratory chain complex I; GO:0032991 macromolecular complex; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0005747 mitochondrial respiratory chain complex I; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0031970 organelle envelope lumen; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0098803 respiratory chain complex; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005739 mitochondrion; GO:0005746 mitochondrial respiratory chain; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0030964 NADH dehydrogenase complex; GO:0005758 mitochondrial intermembrane space; GO:1990204 oxidoreductase complex; GO:0031975 envelope; GO:0043234 protein complex; GO:0031966 mitochondrial membrane; GO:0070469 respiratory chain; GO:0044444 cytoplasmic part; ","GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:0003954 NADH dehydrogenase activity; GO:0003824 catalytic activity; GO:0050136 NADH dehydrogenase (quinone) activity; GO:0008137 NADH dehydrogenase (ubiquinone) activity; GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; GO:0016491 oxidoreductase activity; ","K03963","NDUFB7; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7","hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); "]
["P17612","cAMP-dependent protein kinase catalytic subunit alpha OS=Homo sapiens OX=9606 GN=PRKACA","PRKACA",40.589,49.899,22.8,8,13,4,0.982,1.048,0.991,0.947,1.023,1,0.983,0.606,"mitochondria\r",{"$cut":{"chars":17335,"head":"GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0021700 developmental maturation; GO:0022414 reproductive process; GO:0035148 tube formation; GO:0043009 chordate embryonic development; GO:0042593 glucose homeostasis; GO:0031347 regulation of defense response; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0044782 cilium organization; GO:0010469 regulation of receptor activity; GO:0061337 cardiac conduction; GO:0008152 metabolic process; GO:0007286 spermatid development; GO:1901019 regulation of calcium ion transmembrane transporter activity; GO:0044093 positive regulation of molecular function; GO:0055065 metal ion homeostasis; GO:0071322 cellular response to carbohydrate stimulus; GO:0044057 regulation of system process; GO:0044770 cell cycle phase transition; GO:0090068 positive regulation of cell cycle process; GO:0009790 embryo development; GO:0048598 embryonic morphogenesis; GO:0045667 regulation of osteoblast differentiation; GO:0006396 RNA processing; GO:0042325 regulation of phosphorylation; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0071374 cellular response to parathyroid hormone stimulus; GO:0035239 tube morphogenesis; GO:0044763 single-organism cellular process; GO:0019932 second-messenger-mediated signaling; GO:0010506 regulation of autophagy; GO:0006874 cellular calcium ion homeostasis; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0016241 regulation of macroautophagy; GO:0010243 response to organonitrogen compound; GO:0002223 stimulatory C-type lectin receptor signaling pathway; GO:0030104 water homeostasis; GO:0046825 regulation of protein export from nucleus; GO:0061136 regulation of proteasomal protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:1901698 response to nitrogen compound; GO:2001257 regulation of cation channel activity; GO:0051223 regulation of protein transport; GO:0032412 regulation of ion transmembrane transporter activity; GO:0016071 mRNA metabolic process; GO:0048609 multicellular organismal reproductive process; GO:0000003 reproduction; GO:0002009 morphogenesis of an epithelium; GO:0016310 phosphorylation; GO:0044707 single-multicellular organism process; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:1901700 response to oxygen-containing compound; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0009653 anatomical structure morphogenesis; GO:0023057 negative regulation of signaling; GO:0045992 negative regulation of embryonic development; GO:0010648 negative regulation of cell communication; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0033500 carbohydrate homeostasis; GO:0010959 regulation of metal ion transport; GO:0016331 morphogenesis of embryonic epithelium; GO:0042176 regulation of protein catabolic process; GO:0050848 regulation of calcium-mediated signaling; GO:0050778 positive regulation of immune response; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0048878 chemical homeostasis; GO:0032409 regulation of transporter activity; GO:0060562 epithelial tube morphogenesis; GO:0051282 regulation of sequestering of calcium ion; GO:0006950 response to stress; GO:0051960 regulation of nervous system development; GO:0050804 modulation of synaptic transmission; GO:0003014 renal system process; GO:0051924 regulation of calcium ion transport; GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0006996 organelle organization; GO:0050891 multicellular organismal water homeostasis; GO:0031325 positive regulation of cellular metabolic process; GO:0030278 regulation of ossification; GO:0070613 regulation of protein proce"}},"GO:0030425 dendrite; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0098857 membrane microdomain; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0097729 9+2 motile cilium; GO:0005623 cell; GO:1902911 protein kinase complex; GO:0044422 organelle part; GO:0043197 dendritic spine; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0098590 plasma membrane region; GO:0016607 nuclear speck; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0098589 membrane region; GO:0043005 neuron projection; GO:0034702 ion channel complex; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0005929 cilium; GO:0042995 cell projection; GO:0044430 cytoskeletal part; GO:0034703 cation channel complex; GO:0031981 nuclear lumen; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0098794 postsynapse; GO:0045171 intercellular bridge; GO:0043234 protein complex; GO:0097223 sperm part; GO:0043230 extracellular organelle; GO:0061695 transferase complex, transferring phosphorus-containing groups; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0036126 sperm flagellum; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005856 cytoskeleton; GO:0031974 membrane-enclosed lumen; GO:0005815 microtubule organizing center; GO:1902494 catalytic complex; GO:0044309 neuron spine; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0044441 ciliary part; GO:0044425 membrane part; GO:0044464 cell part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0030141 secretory granule; GO:0045121 membrane raft; GO:1990351 transporter complex; GO:0044456 synapse part; GO:0097546 ciliary base; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0031588 nucleotide-activated protein kinase complex; GO:0043232 intracellular non-membrane-bounded organelle; GO:0031594 neuromuscular junction; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:1990234 transferase complex; GO:1902495 transmembrane transporter complex; GO:0044463 cell projection part; GO:0031514 motile cilium; GO:0005829 cytosol; GO:0016021 integral component of membrane; GO:0034704 calcium channel complex; GO:0045202 synapse; GO:0005952 cAMP-dependent protein kinase complex; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0044853 plasma membrane raft; GO:0001669 acrosomal vesicle; GO:0005813 centrosome; GO:0097225 sperm midpiece; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0051018 protein kinase A binding; GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0031625 ubiquitin protein ligase binding; GO:0019901 protein kinase binding; GO:0005515 protein binding; GO:0004672 protein kinase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016301 kinase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0004691 cAMP-dependent protein kinase activity; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0004690 cyclic nucleotide-dependent protein kinase activity; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0034237 protein kinase A regulatory subunit binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0019900 kinase binding; GO:0004712 protein serine/threonine/tyrosine kinase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0004674 protein serine/threonine kinase activity; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0019899 enzyme binding; GO:0036094 small molecule binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K04345","PKA; protein kinase A [EC:2.7.11.11]","hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human); hsa04530 Tight junction - Homo sapiens (human); hsa04014 Ras signaling pathway - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa04970 Salivary secretion - Homo sapiens (human); hsa04962 Vasopressin-regulated water reabsorption - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa04934 Cushing's syndrome - Homo sapiens (human); hsa04922 Glucagon signaling pathway - Homo sapiens (human); hsa04211 Longevity regulating pathway - Homo sapiens (human); hsa04611 Platelet activation - Homo sapiens (human); hsa04340 Hedgehog signaling pathway - Homo sapiens (human); hsa04971 Gastric acid secretion - Homo sapiens (human); hsa04914 Progesterone-mediated oocyte maturation - Homo sapiens (human); hsa04725 Cholinergic synapse - Homo sapiens (human); hsa04921 Oxytocin signaling pathway - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); hsa04371 Apelin signaling pathway - Homo sapiens (human); hsa05031 Amphetamine addiction - Homo sapiens (human); hsa04916 Melanogenesis - Homo sapiens (human); hsa04020 Calcium signaling pathway - Homo sapiens (human); hsa04270 Vascular smooth muscle contraction - Homo sapiens (human); hsa04923 Regulation of lipolysis in adipocytes - Homo sapiens (human); hsa04010 MAPK signaling pathway - Homo sapiens (human); hsa04750 Inflammatory mediator regulation of TRP channels - Homo sapiens (human); hsa04740 Olfactory transduction - Homo sapiens (human); hsa05414 Dilated cardiomyopathy (DCM) - Homo sapiens (human); hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human); hsa04540 Gap junction - Homo sapiens (human); hsa04912 GnRH signaling pathway - Homo sapiens (human); hsa04727 GABAergic synapse - Homo sapiens (human); hsa05020 Prion diseases - Homo sapiens (human); hsa05203 Viral carcinogenesis - Homo sapiens (human); hsa04742 Taste transduction - Homo sapiens (human); hsa04720 Long-term potentiation - Homo sapiens (human); hsa04713 Circadian entrainment - Homo sapiens (human); hsa04928 Parathyroid hormone synthesis, secretion and action - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa05166 HTLV-I infection - Homo sapiens (human); hsa04924 Renin secretion - Homo sapiens (human); hsa05110 Vibrio cholerae infection - Homo sapiens (human); hsa04976 Bile secretion - Homo sapiens (human); hsa04911 Insulin secretion - Homo sapiens (human); hsa04724 Glutamatergic synapse - Homo sapiens (human); hsa04140 Autophagy - animal - Homo sapiens (human); hsa04114 Oocyte meiosis - Homo sapiens (human); hsa01522 Endocrine resistance - Homo sapiens (human); hsa05034 Alcoholism - Homo sapiens (human); hsa04927 Cortisol synthesis and secretion - Homo sapiens (human); hsa04915 Estrogen signaling pathway - Homo sapiens (human); hsa04310 Wnt signaling pathway - Homo sapiens (human); hsa05032 Morphine addiction - Homo sapiens (human); hsa04728 Dopaminergic synapse - Homo sapiens (human); hsa04910 Insulin signaling pathway - Homo sapiens (human); hsa04024 cAMP signaling pathway - Homo sapiens (human); hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa05030 Cocaine addiction - Homo sapiens (human); hsa04726 Serotonergic synapse - Homo sapiens (human); hsa04213 Longevity regulating pathway - multiple species - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); hsa04062 Chemokine signaling pathway - Homo sapiens (human); hsa04925 Aldosterone synthesis and secretion - Homo sapiens (human); hsa04913 Ovarian steroidogenesis - Homo sapiens (human); hsa05146 Amoebiasis - Homo sapiens (human); hsa04918 Thyroid hormone synthesis - Homo sapiens (human); hsa04926 Relaxin signaling pathway - Homo sapiens (human); hsa04961 Endocrine and other factor-regulated calcium reabsorption - Homo sapiens (human); ","IPR000719; IPR011009; IPR000961; ","\"Protein kinase domain; Protein kinase-like domain; AGC-kinase, C-terminal; \"\r"]
["P17655","Calpain-2 catalytic subunit OS=Homo sapiens OX=9606 GN=CAPN2","CAPN2",79.994,87.675,23,14,22,14,1.075,1.111,1.057,0.906,0.901,0.926,0.843,0.000536,"cytoplasm\r","GO:0001101 response to acid chemical; GO:0014902 myotube differentiation; GO:0043009 chordate embryonic development; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0016485 protein processing; GO:0044237 cellular metabolic process; GO:0006949 syncytium formation; GO:0008152 metabolic process; GO:0022617 extracellular matrix disassembly; GO:0009719 response to endogenous stimulus; GO:0051493 regulation of cytoskeleton organization; GO:0030198 extracellular matrix organization; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0009790 embryo development; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0043200 response to amino acid; GO:0051716 cellular response to stimulus; GO:0044763 single-organism cellular process; GO:0032501 multicellular organismal process; GO:0071417 cellular response to organonitrogen compound; GO:1901575 organic substance catabolic process; GO:0010243 response to organonitrogen compound; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:1901699 cellular response to nitrogen compound; GO:0001701 in utero embryonic development; GO:0030163 protein catabolic process; GO:0071230 cellular response to amino acid stimulus; GO:1901698 response to nitrogen compound; GO:0044260 cellular macromolecule metabolic process; GO:0048856 anatomical structure development; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0009628 response to abiotic stimulus; GO:0071310 cellular response to organic substance; GO:1901700 response to oxygen-containing compound; GO:0044267 cellular protein metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0016540 protein autoprocessing; GO:0009653 anatomical structure morphogenesis; GO:0030154 cell differentiation; GO:0071229 cellular response to acid chemical; GO:0043062 extracellular structure organization; GO:0001666 response to hypoxia; GO:0070482 response to oxygen levels; GO:0044248 cellular catabolic process; GO:0061061 muscle structure development; GO:0006508 proteolysis; GO:0007275 multicellular organism development; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0009987 cellular process; GO:0051146 striated muscle cell differentiation; GO:0044265 cellular macromolecule catabolic process; GO:0006950 response to stress; GO:0009792 embryo development ending in birth or egg hatching; GO:0000768 syncytium formation by plasma membrane fusion; GO:0033043 regulation of organelle organization; GO:0001824 blastocyst development; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901701 cellular response to oxygen-containing compound; GO:0007520 myoblast fusion; GO:0071495 cellular response to endogenous stimulus; GO:0044767 single-organism developmental process; GO:0009057 macromolecule catabolic process; GO:0022411 cellular component disassembly; GO:0042692 muscle cell differentiation; GO:0010467 gene expression; GO:0036293 response to decreased oxygen levels; GO:0051128 regulation of cellular component organization; GO:0051604 protein maturation; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0030425 dendrite; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0005938 cell cortex; GO:0097038 perinuclear endoplasmic reticulum; GO:0098857 membrane microdomain; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0099568 cytoplasmic region; GO:0005737 cytoplasm; GO:0030863 cortical cytoskeleton; GO:0030864 cortical actin cytoskeleton; GO:0044424 intracellular part; GO:0005623 cell; GO:0031143 pseudopodium; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005856 cytoskeleton; GO:0005925 focal adhesion; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005694 chromosome; GO:0098805 whole membrane; GO:0005764 lysosome; GO:0098589 membrane region; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0043005 neuron projection; GO:0030055 cell-substrate junction; GO:0045121 membrane raft; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0005924 cell-substrate adherens junction; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0015629 actin cytoskeleton; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0036477 somatodendritic compartment; GO:0000785 chromatin; GO:0044432 endoplasmic reticulum part; GO:0044448 cell cortex part; GO:0005773 vacuole; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0004198 calcium-dependent cysteine-type endopeptidase activity; GO:0008233 peptidase activity; GO:0046982 protein heterodimerization activity; GO:0043167 ion binding; GO:0046983 protein dimerization activity; GO:0016787 hydrolase activity; GO:0008234 cysteine-type peptidase activity; GO:0005515 protein binding; GO:0004175 endopeptidase activity; GO:0008092 cytoskeletal protein binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005509 calcium ion binding; GO:0004197 cysteine-type endopeptidase activity; ","K03853","CAPN2; calpain-2 [EC:3.4.22.53]","hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04218 Cellular senescence - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa04210 Apoptosis - Homo sapiens (human); hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); hsa04217 Necroptosis - Homo sapiens (human); ","IPR022683; IPR022682; IPR011992; IPR033883; IPR002048; IPR001300; ","\"Peptidase C2, calpain, domain III; Peptidase C2, calpain, large subunit, domain III; EF-hand domain pair; Calpain subdomain III; EF-hand domain; Peptidase C2, calpain, catalytic domain; \"\r"]
["P17661","Desmin OS=Homo sapiens OX=9606 GN=DES","DES",53.535,247.81,62.6,33,93,28,1.183,1.197,1.183,0.79,0.835,0.815,0.685,2.07e-05,"mitochondria\r","GO:0030048 actin filament-based movement; GO:0016043 cellular component organization; GO:0030049 muscle filament sliding; GO:0070252 actin-mediated cell contraction; GO:0003012 muscle system process; GO:0045109 intermediate filament organization; GO:0003008 system process; GO:0045104 intermediate filament cytoskeleton organization; GO:0033275 actin-myosin filament sliding; GO:1903522 regulation of blood circulation; GO:0045103 intermediate filament-based process; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0008016 regulation of heart contraction; GO:0032501 multicellular organismal process; GO:0051239 regulation of multicellular organismal process; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0006936 muscle contraction; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0044057 regulation of system process; GO:0006928 movement of cell or subcellular component; GO:0007010 cytoskeleton organization; GO:0097435 supramolecular fiber organization; GO:0009987 cellular process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0044291 cell-cell contact zone; GO:0030054 cell junction; GO:0030016 myofibril; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0005913 cell-cell adherens junction; GO:0030018 Z disc; GO:0005911 cell-cell junction; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0031674 I band; GO:0014704 intercalated disc; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0043292 contractile fiber; GO:0005916 fascia adherens; GO:0043227 membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0031594 neuromuscular junction; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0045202 synapse; GO:0099081 supramolecular polymer; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0045111 intermediate filament cytoskeleton; GO:0005882 intermediate filament; GO:0030017 sarcomere; GO:0044449 contractile fiber part; GO:0042383 sarcolemma; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0008092 cytoskeletal protein binding; GO:0042802 identical protein binding; GO:0005200 structural constituent of cytoskeleton; GO:0005198 structural molecule activity; GO:0005488 binding; ","K07610","DES; desmin","hsa05414 Dilated cardiomyopathy (DCM) - Homo sapiens (human); hsa05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human); hsa05410 Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human); ","IPR006821; ","\"Intermediate filament head, DNA-binding domain; \"\r"]
["P17812","CTP synthase 1 OS=Homo sapiens OX=9606 GN=CTPS1","CTPS1",66.69,14.854,8.8,4,4,3,0.914,0.858,0.833,1.213,1.152,1.028,1.302,0.00938,"cytoplasm\r","GO:0009116 nucleoside metabolic process; GO:0046132 pyrimidine ribonucleoside biosynthetic process; GO:0045321 leukocyte activation; GO:0009147 pyrimidine nucleoside triphosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009163 nucleoside biosynthetic process; GO:0009058 biosynthetic process; GO:0046036 CTP metabolic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0042110 T cell activation; GO:0046390 ribose phosphate biosynthetic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0006213 pyrimidine nucleoside metabolic process; GO:0046134 pyrimidine nucleoside biosynthetic process; GO:0006753 nucleoside phosphate metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0072527 pyrimidine-containing compound metabolic process; GO:0032943 mononuclear cell proliferation; GO:0018130 heterocycle biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0046131 pyrimidine ribonucleoside metabolic process; GO:0090407 organophosphate biosynthetic process; GO:0042221 response to chemical; GO:0044710 single-organism metabolic process; GO:0070661 leukocyte proliferation; GO:0044210 'de novo' CTP biosynthetic process; GO:1901657 glycosyl compound metabolic process; GO:0006082 organic acid metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0043436 oxoacid metabolic process; GO:0009201 ribonucleoside triphosphate biosynthetic process; GO:0009165 nucleotide biosynthetic process; GO:0009208 pyrimidine ribonucleoside triphosphate metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0009259 ribonucleotide metabolic process; GO:0015949 nucleobase-containing small molecule interconversion; GO:0009142 nucleoside triphosphate biosynthetic process; GO:0006541 glutamine metabolic process; GO:0006221 pyrimidine nucleotide biosynthetic process; GO:0046651 lymphocyte proliferation; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0072528 pyrimidine-containing compound biosynthetic process; GO:0042493 response to drug; GO:0006241 CTP biosynthetic process; GO:0009220 pyrimidine ribonucleotide biosynthetic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:1901135 carbohydrate derivative metabolic process; GO:0042100 B cell proliferation; GO:0034641 cellular nitrogen compound metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009119 ribonucleoside metabolic process; GO:0009987 cellular process; GO:0042113 B cell activation; GO:0009218 pyrimidine ribonucleotide metabolic process; GO:0009064 glutamine family amino acid metabolic process; GO:0044711 single-organism biosynthetic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0046649 lymphocyte activation; GO:0008283 cell proliferation; GO:0009141 nucleoside triphosphate metabolic process; GO:0009148 pyrimidine nucleoside triphosphate biosynthetic process; GO:0002376 immune system process; GO:0042455 ribonucleoside biosynthetic process; GO:1901605 alpha-amino acid metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0006220 pyrimidine nucleotide metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006793 phosphorus metabolic process; GO:1901659 glycosyl compound biosynthetic process; GO:0009260 ribonucleotide biosynthetic process; GO:0019752 carboxylic acid metabolic process; GO:0001775 cell activation; GO:0019637 organophosphate metabolic process; GO:0042098 T cell proliferation; GO:0009209 pyrimidine ribonucleoside triphosphate biosynthetic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0016874 ligase activity; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0016879 ligase activity, forming carbon-nitrogen bonds; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0003883 CTP synthase activity; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K01937","pyrG; CTP synthase [EC:6.3.4.2]","hsa00240 Pyrimidine metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR017456; IPR027417; IPR017926; IPR033828; IPR029062; ","\"CTP synthase, N-terminal; P-loop containing nucleoside triphosphate hydrolase; Glutamine amidotransferase; CTP synthase GATase domain; Class I glutamine amidotransferase-like; \"\r"]
["P17844","Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5","DDX5",69.147,59.937,30.5,19,37,12,0.824,0.751,0.742,1.247,1.276,1.201,1.607,2.22E-4,"nucleus\r","GO:0044700 single organism signaling; GO:0000381 regulation of alternative mRNA splicing, via spliceosome; GO:0097659 nucleic acid-templated transcription; GO:0009891 positive regulation of biosynthetic process; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0043170 macromolecule metabolic process; GO:0045667 regulation of osteoblast differentiation; GO:0006396 RNA processing; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0016049 cell growth; GO:0060765 regulation of androgen receptor signaling pathway; GO:0045893 positive regulation of transcription, DNA-templated; GO:0000122 negative regulation of transcription from RNA polymerase II promoter; GO:0044763 single-organism cellular process; GO:0032774 RNA biosynthetic process; GO:0050684 regulation of mRNA processing; GO:0031323 regulation of cellular metabolic process; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0080135 regulation of cellular response to stress; GO:1901798 positive regulation of signal transduction by p53 class mediator; GO:0006402 mRNA catabolic process; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0048641 regulation of skeletal muscle tissue development; GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator; GO:0097190 apoptotic signaling pathway; GO:2001020 regulation of response to DNA damage stimulus; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0080134 regulation of response to stress; GO:0051239 regulation of multicellular organismal process; GO:0045892 negative regulation of transcription, DNA-templated; GO:0044270 cellular nitrogen compound catabolic process; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0009299 mRNA transcription; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0000375 RNA splicing, via transesterification reactions; GO:0044248 cellular catabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0034655 nucleobase-containing compound catabolic process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0010501 RNA secondary structure unwinding; GO:0008380 RNA splicing; GO:0009966 regulation of signal transduction; GO:0051254 positive regulation of RNA metabolic process; GO:1902531 regulation of intracellular signal transduction; GO:0043900 regulation of multi-organism process; GO:0072331 signal transduction by p53 class mediator; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0043484 regulation of RNA splicing; GO:0009890 negative regulation of biosynthetic process; GO:1903311 regulation of mRNA metabolic process; GO:0030278 regulation of ossification; GO:0031325 positive regulation of cellular metabolic process; GO:0012501 programmed cell death; GO:0031328 positive regulation of cellular biosynthetic process; GO:0048584 positive regulation of response to stimulus; GO:0040007 growth; GO:0050793 regulation of developmental process; GO:0048634 regulation of muscle organ development; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:2001014 regulation of skeletal muscle cell differentiation; GO:0051253 negative regulation of RNA metabolic process; GO:0033145 positive regulation of intracellular steroid hormone receptor signaling pathway; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0006915 apoptotic process; GO:1901361 organic cyclic compound catabolic process; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0048024 regulation of mRNA splicing, via spliceosome; GO:2001022 positive regulation of response to DNA damage stimulus; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0045069 regulation of viral genome replication; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:0006401 RNA catabolic process; GO:0016202 regulation of striated muscle tissue development; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:1902679 negative regulation of RNA biosynthetic process; GO:0019222 regulation of metabolic process; GO:0033143 regulation of intracellular steroid hormone receptor signaling pathway; GO:2000026 regulation of multicellular organismal development; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0097193 intrinsic apoptotic signaling pathway; GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator; GO:0071704 organic substance metabolic process; GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway; GO:0000398 mRNA splicing, via spliceosome; GO:0023056 positive regulation of signaling; GO:1901796 regulation of signal transduction by p53 class mediator; GO:0034641 cellular nitrogen compound metabolic process; GO:0010647 positive regulation of cell communication; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0035556 intracellular signal transduction; GO:0010629 negative regulation of gene expression; GO:1901861 regulation of muscle tissue development; GO:0050792 regulation of viral process; GO:0006807 nitrogen compound metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0008219 cell death; GO:0033146 regulation of intracellular estrogen receptor signaling pathway; GO:0048511 rhythmic process; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0009967 positive regulation of signal transduction; GO:1903900 regulation of viral life cycle; GO:0009056 catabolic process; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005681 spliceosomal complex; GO:0005730 nucleolus; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031012 extracellular matrix; GO:0005634 nucleus; GO:0071013 catalytic step 2 spliceosome; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043230 extracellular organelle; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0005102 receptor binding; GO:0008026 ATP-dependent helicase activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0050681 androgen receptor binding; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0051427 hormone receptor binding; GO:0048306 calcium-dependent protein binding; GO:0016887 ATPase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0003729 mRNA binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0035258 steroid hormone receptor binding; GO:0036002 pre-mRNA binding; GO:0043168 anion binding; GO:0004004 ATP-dependent RNA helicase activity; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003723 RNA binding; GO:0030331 estrogen receptor binding; GO:0070035 purine NTP-dependent helicase activity; GO:0005524 ATP binding; GO:0004386 helicase activity; GO:0003730 mRNA 3'-UTR binding; GO:0044877 macromolecular complex binding; GO:0001882 nucleoside binding; GO:0008186 RNA-dependent ATPase activity; GO:0043167 ion binding; GO:0000166 nucleotide binding; GO:0003712 transcription cofactor activity; GO:0017111 nucleoside-triphosphatase activity; GO:0005516 calmodulin binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003724 RNA helicase activity; GO:0003676 nucleic acid binding; GO:0042623 ATPase activity, coupled; GO:0035257 nuclear hormone receptor binding; GO:0003713 transcription coactivator activity; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0000988 transcription factor activity, protein binding; GO:0019899 enzyme binding; GO:0043021 ribonucleoprotein complex binding; GO:0036094 small molecule binding; ","K12823","DDX5; ATP-dependent RNA helicase DDX5/DBP2 [EC:3.6.4.13]","hsa03040 Spliceosome - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human); ","IPR011545; IPR014014; IPR014001; IPR027417; IPR001650; ","\"DEAD/DEAH box helicase domain; RNA helicase, DEAD-box type, Q motif; Helicase superfamily 1/2, ATP-binding domain; P-loop containing nucleoside triphosphate hydrolase; Helicase, C-terminal; \"\r"]
["P17858","ATP-dependent 6-phosphofructokinase, liver type OS=Homo sapiens OX=9606 GN=PFKL","PFKL",85.018,136.91,29,21,34,17,1.06,0.995,1.02,0.956,0.977,1.012,0.958,0.157,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0009116 nucleoside metabolic process; GO:0045321 leukocyte activation; GO:0006165 nucleoside diphosphate phosphorylation; GO:0019362 pyridine nucleotide metabolic process; GO:0006096 glycolytic process; GO:0050796 regulation of insulin secretion; GO:0006002 fructose 6-phosphate metabolic process; GO:0009185 ribonucleoside diphosphate metabolic process; GO:0009749 response to glucose; GO:0044237 cellular metabolic process; GO:0006006 glucose metabolic process; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0032879 regulation of localization; GO:0065003 macromolecular complex assembly; GO:0032787 monocarboxylic acid metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0009743 response to carbohydrate; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0051051 negative regulation of transport; GO:0050709 negative regulation of protein secretion; GO:0002443 leukocyte mediated immunity; GO:0009179 purine ribonucleoside diphosphate metabolic process; GO:0044281 small molecule metabolic process; GO:1903531 negative regulation of secretion by cell; GO:0044763 single-organism cellular process; GO:0061620 glycolytic process through glucose-6-phosphate; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0006732 coenzyme metabolic process; GO:0005975 carbohydrate metabolic process; GO:0061718 glucose catabolic process to pyruvate; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0046883 regulation of hormone secretion; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0019674 NAD metabolic process; GO:0044710 single-organism metabolic process; GO:0034284 response to monosaccharide; GO:0010817 regulation of hormone levels; GO:0051223 regulation of protein transport; GO:0009126 purine nucleoside monophosphate metabolic process; GO:0043436 oxoacid metabolic process; GO:0030388 fructose 1,6-bisphosphate metabolic process; GO:0050794 regulation of cellular process; GO:0016310 phosphorylation; GO:0002283 neutrophil activation involved in immune response; GO:0051260 protein homooligomerization; GO:0046496 nicotinamide nucleotide metabolic process; GO:0009259 ribonucleotide metabolic process; GO:1901700 response to oxygen-containing compound; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0006735 NADH regeneration; GO:0051259 protein oligomerization; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0032880 regulation of protein localization; GO:0009119 ribonucleoside metabolic process; GO:0006461 protein complex assembly; GO:0090087 regulation of peptide transport; GO:0051224 negative regulation of protein transport; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0009141 nucleoside triphosphate metabolic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0002263 cell activation involved in immune response; GO:0006163 purine nucleotide metabolic process; GO:0045055 regulated exocytosis; GO:0046888 negative regulation of hormone secretion; GO:0006793 phosphorus metabolic process; GO:0001775 cell activation; GO:0019637 organophosphate metabolic process; GO:0019320 hexose catabolic process; GO:0051179 localization; GO:0006955 immune response; GO:0006887 exocytosis; GO:0019318 hexose metabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0006757 ATP generation from ADP; GO:0046365 monosaccharide catabolic process; GO:0042278 purine nucleoside metabolic process; GO:0046031 ADP metabolic process; GO:0009746 response to hexose; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0023051 regulation of signaling; GO:0009117 nucleotide metabolic process; GO:0051046 regulation of secretion; GO:0044699 single-organism process; GO:0046939 nucleotide phosphorylation; GO:0009135 purine nucleoside diphosphate metabolic process; GO:0072524 pyridine-containing compound metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0061615 glycolytic process through fructose-6-phosphate; GO:0051234 establishment of localization; GO:0010646 regulation of cell communication; GO:0090278 negative regulation of peptide hormone secretion; GO:0022607 cellular component assembly; GO:0051262 protein tetramerization; GO:0006753 nucleoside phosphate metabolic process; GO:0002274 myeloid leukocyte activation; GO:0071822 protein complex subunit organization; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0055114 oxidation-reduction process; GO:0002446 neutrophil mediated immunity; GO:1901360 organic cyclic compound metabolic process; GO:1903530 regulation of secretion by cell; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0002792 negative regulation of peptide secretion; GO:0002444 myeloid leukocyte mediated immunity; GO:0051186 cofactor metabolic process; GO:0016052 carbohydrate catabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0051048 negative regulation of secretion; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0032940 secretion by cell; GO:0043299 leukocyte degranulation; GO:1901657 glycosyl compound metabolic process; GO:0006082 organic acid metabolic process; GO:0070271 protein complex biogenesis; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0002252 immune effector process; GO:0006734 NADH metabolic process; GO:0050896 response to stimulus; GO:0070201 regulation of establishment of protein localization; GO:0071704 organic substance metabolic process; GO:0061621 canonical glycolysis; GO:0002791 regulation of peptide secretion; GO:0006090 pyruvate metabolic process; GO:0051289 protein homotetramerization; GO:0005996 monosaccharide metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0036230 granulocyte activation; GO:0050708 regulation of protein secretion; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0009132 nucleoside diphosphate metabolic process; GO:0046034 ATP metabolic process; GO:0044724 single-organism carbohydrate catabolic process; GO:0051049 regulation of transport; GO:0044712 single-organism catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044282 small molecule catabolic process; GO:0043312 neutrophil degranulation; GO:0043933 macromolecular complex subunit organization; GO:0002366 leukocyte activation involved in immune response; GO:0046128 purine ribonucleoside metabolic process; GO:0006007 glucose catabolic process; GO:0042119 neutrophil activation; GO:0090276 regulation of peptide hormone secretion; GO:0019752 carboxylic acid metabolic process; GO:1904950 negative regulation of establishment of protein localization; GO:0046676 negative regulation of insulin secretion; GO:0009150 purine ribonucleotide metabolic process; GO:0009056 catabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0034774 secretory granule lumen; GO:0044421 extracellular region part; GO:0061695 transferase complex, transferring phosphorus-containing groups; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0044445 cytosolic part; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0005945 6-phosphofructokinase complex; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:1990234 transferase complex; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0003872 6-phosphofructokinase activity; GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0005515 protein binding; GO:0048029 monosaccharide binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016301 kinase activity; GO:0042802 identical protein binding; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0070061 fructose binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0019900 kinase binding; GO:0032549 ribonucleoside binding; GO:0019200 carbohydrate kinase activity; GO:0097367 carbohydrate derivative binding; GO:0008443 phosphofructokinase activity; GO:0046872 metal ion binding; GO:0030246 carbohydrate binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019899 enzyme binding; GO:0070095 fructose-6-phosphate binding; GO:0036094 small molecule binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K00850","pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]","hsa00051 Fructose and mannose metabolism - Homo sapiens (human); hsa04066 HIF-1 signaling pathway - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa04922 Glucagon signaling pathway - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); hsa05230 Central carbon metabolism in cancer - Homo sapiens (human); hsa04152 AMPK signaling pathway - Homo sapiens (human); hsa03018 RNA degradation - Homo sapiens (human); hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human); hsa00030 Pentose phosphate pathway - Homo sapiens (human); hsa00052 Galactose metabolism - Homo sapiens (human); hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human); hsa01230 Biosynthesis of amino acids - Homo sapiens (human); ","IPR000023; ","Phosphofructokinase domain; \r"]
["P17900","Ganglioside GM2 activator OS=Homo sapiens OX=9606 GN=GM2A","GM2A",20.838,16.702,34.7,6,12,6,0.796,0.774,0.78,1.184,1.244,1.206,1.546,1.64e-05,"extracellular\r","GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0019377 glycolipid catabolic process; GO:0006643 membrane lipid metabolic process; GO:0006672 ceramide metabolic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0006689 ganglioside catabolic process; GO:0050877 neurological system process; GO:0051234 establishment of localization; GO:0007610 behavior; GO:0008152 metabolic process; GO:0044093 positive regulation of molecular function; GO:0006665 sphingolipid metabolic process; GO:0033036 macromolecule localization; GO:0002274 myeloid leukocyte activation; GO:0046903 secretion; GO:0006629 lipid metabolic process; GO:0044765 single-organism transport; GO:0046466 membrane lipid catabolic process; GO:0002443 leukocyte mediated immunity; GO:0006869 lipid transport; GO:0001573 ganglioside metabolic process; GO:0002446 neutrophil mediated immunity; GO:0006664 glycolipid metabolic process; GO:0044763 single-organism cellular process; GO:0046514 ceramide catabolic process; GO:0043603 cellular amide metabolic process; GO:0005975 carbohydrate metabolic process; GO:0032501 multicellular organismal process; GO:0002444 myeloid leukocyte mediated immunity; GO:0016052 carbohydrate catabolic process; GO:0006810 transport; GO:0044723 single-organism carbohydrate metabolic process; GO:1901575 organic substance catabolic process; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0032940 secretion by cell; GO:0044710 single-organism metabolic process; GO:0065009 regulation of molecular function; GO:0043299 leukocyte degranulation; GO:0044708 single-organism behavior; GO:0044707 single-multicellular organism process; GO:1903509 liposaccharide metabolic process; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0006687 glycosphingolipid metabolic process; GO:0009313 oligosaccharide catabolic process; GO:0050896 response to stimulus; GO:0030149 sphingolipid catabolic process; GO:0071704 organic substance metabolic process; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0051345 positive regulation of hydrolase activity; GO:0050890 cognition; GO:0044248 cellular catabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0051235 maintenance of location; GO:0009311 oligosaccharide metabolic process; GO:0036230 granulocyte activation; GO:0050885 neuromuscular process controlling balance; GO:0009987 cellular process; GO:0016042 lipid catabolic process; GO:0003008 system process; GO:0044724 single-organism carbohydrate catabolic process; GO:0044712 single-organism catabolic process; GO:0016192 vesicle-mediated transport; GO:1901136 carbohydrate derivative catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0010876 lipid localization; GO:0071702 organic substance transport; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:0043312 neutrophil degranulation; GO:0002263 cell activation involved in immune response; GO:0007611 learning or memory; GO:0043085 positive regulation of catalytic activity; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:1901565 organonitrogen compound catabolic process; GO:0019915 lipid storage; GO:0044242 cellular lipid catabolic process; GO:0001775 cell activation; GO:0046479 glycosphingolipid catabolic process; GO:0051179 localization; GO:0006955 immune response; GO:0050905 neuromuscular process; GO:0009056 catabolic process; GO:0065007 biological regulation; GO:1901564 organonitrogen compound metabolic process; GO:0006887 exocytosis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0099568 cytoplasmic region; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0005887 integral component of plasma membrane; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:0090533 cation-transporting ATPase complex; GO:0009898 cytoplasmic side of plasma membrane; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0099738 cell cortex region; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:0043227 membrane-bounded organelle; GO:0045177 apical part of cell; GO:0043233 organelle lumen; GO:0098552 side of membrane; GO:0000323 lytic vacuole; GO:0031226 intrinsic component of plasma membrane; GO:0005576 extracellular region; GO:0043202 lysosomal lumen; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0042582 azurophil granule; GO:0043231 intracellular membrane-bounded organelle; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043230 extracellular organelle; GO:0045179 apical cortex; GO:0034774 secretory granule lumen; GO:0005938 cell cortex; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0098562 cytoplasmic side of membrane; GO:0098533 ATPase dependent transmembrane transport complex; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0044425 membrane part; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:1990351 transporter complex; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:1902495 transmembrane transporter complex; GO:0016021 integral component of membrane; GO:0005889 hydrogen:potassium-exchanging ATPase complex; GO:0043226 organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0044459 plasma membrane part; GO:0044448 cell cortex part; GO:1904949 ATPase complex; GO:0044444 cytoplasmic part; ","GO:0005319 lipid transporter activity; GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds; GO:0022892 substrate-specific transporter activity; GO:0016787 hydrolase activity; GO:0016004 phospholipase activator activity; GO:0098772 molecular function regulator; GO:0032428 beta-N-acetylgalactosaminidase activity; GO:0030234 enzyme regulator activity; GO:0003824 catalytic activity; GO:0016798 hydrolase activity, acting on glycosyl bonds; GO:0060229 lipase activator activity; GO:0004563 beta-N-acetylhexosaminidase activity; GO:0030290 sphingolipid activator protein activity; GO:0008047 enzyme activator activity; GO:0005215 transporter activity; GO:0015929 hexosaminidase activity; ","K12383","GM2A; ganglioside GM2 activator","hsa04142 Lysosome - Homo sapiens (human); ","IPR003172; ","MD-2-related lipid-recognition domain; \r"]
["P17931","Galectin-3 OS=Homo sapiens OX=9606 GN=LGALS3","LGALS3",26.152,41.675,28.4,9,22,9,1.02,1.036,0.998,0.997,1.011,0.956,0.971,0.207,"cyto_nucl\r","GO:0060627 regulation of vesicle-mediated transport; GO:0002694 regulation of leukocyte activation; GO:0030335 positive regulation of cell migration; GO:0010941 regulation of cell death; GO:0045321 leukocyte activation; GO:0032944 regulation of mononuclear cell proliferation; GO:2001189 negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell; GO:0002698 negative regulation of immune effector process; GO:0044237 cellular metabolic process; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0032879 regulation of localization; GO:2000521 negative regulation of immunological synapse formation; GO:0043170 macromolecule metabolic process; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0006396 RNA processing; GO:0051051 negative regulation of transport; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:1903038 negative regulation of leukocyte cell-cell adhesion; GO:0043269 regulation of ion transport; GO:0044763 single-organism cellular process; GO:0050670 regulation of lymphocyte proliferation; GO:0051272 positive regulation of cellular component movement; GO:0048870 cell motility; GO:0006935 chemotaxis; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0050900 leukocyte migration; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0042330 taxis; GO:0002682 regulation of immune system process; GO:0071677 positive regulation of mononuclear cell migration; GO:0002685 regulation of leukocyte migration; GO:0071675 regulation of mononuclear cell migration; GO:0016071 mRNA metabolic process; GO:0060548 negative regulation of cell death; GO:0002687 positive regulation of leukocyte migration; GO:0030855 epithelial cell differentiation; GO:0050794 regulation of cellular process; GO:0002283 neutrophil activation involved in immune response; GO:0007162 negative regulation of cell adhesion; GO:0042127 regulation of cell proliferation; GO:0043067 regulation of programmed cell death; GO:0050860 negative regulation of T cell receptor signaling pathway; GO:0022408 negative regulation of cell-cell adhesion; GO:2000147 positive regulation of cell motility; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0060326 cell chemotaxis; GO:0050866 negative regulation of cell activation; GO:0045806 negative regulation of endocytosis; GO:0097530 granulocyte migration; GO:0023057 negative regulation of signaling; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0010648 negative regulation of cell communication; GO:0006139 nucleobase-containing compound metabolic process; GO:2000145 regulation of cell motility; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:0010959 regulation of metal ion transport; GO:0008380 RNA splicing; GO:0009966 regulation of signal transduction; GO:0070232 regulation of T cell apoptotic process; GO:0051928 positive regulation of calcium ion transport; GO:1905517 macrophage migration; GO:0030100 regulation of endocytosis; GO:0006950 response to stress; GO:0051270 regulation of cellular component movement; GO:0016192 vesicle-mediated transport; GO:0051924 regulation of calcium ion transport; GO:0030334 regulation of cell migration; GO:2001237 negative regulation of extrinsic apoptotic signaling pathway; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:0002548 monocyte chemotaxis; GO:0002263 cell activation involved in immune response; GO:0030155 regulation of cell adhesion; GO:0071674 mononuclear cell migration; GO:0043270 positive regulation of ion transport; GO:0045055 regulated exocytosis; GO:0001775 cell activation; GO:0006928 movement of cell or subcellular component; GO:0006955 immune response; GO:0051179 localization; GO:0006887 exocytosis; GO:0050863 regulation of T cell activation; GO:2001188 regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell; GO:0009968 negative regulation of signal transduction; GO:0051674 localization of cell; GO:0040017 positive regulation of locomotion; GO:0023051 regulation of signaling; GO:0051129 negative regulation of cellular component organization; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0051249 regulation of lymphocyte activation; GO:0050858 negative regulation of antigen receptor-mediated signaling pathway; GO:0048246 macrophage chemotaxis; GO:0051234 establishment of localization; GO:1990266 neutrophil migration; GO:2001233 regulation of apoptotic signaling pathway; GO:0010646 regulation of cell communication; GO:0071621 granulocyte chemotaxis; GO:0097529 myeloid leukocyte migration; GO:0070663 regulation of leukocyte proliferation; GO:0050777 negative regulation of immune response; GO:0002695 negative regulation of leukocyte activation; GO:0002697 regulation of immune effector process; GO:0070887 cellular response to chemical stimulus; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0009888 tissue development; GO:0002446 neutrophil mediated immunity; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0090280 positive regulation of calcium ion import; GO:0002444 myeloid leukocyte mediated immunity; GO:0051050 positive regulation of transport; GO:0006397 mRNA processing; GO:0002683 negative regulation of immune system process; GO:0016070 RNA metabolic process; GO:0030593 neutrophil chemotaxis; GO:0050789 regulation of biological process; GO:0050865 regulation of cell activation; GO:0042221 response to chemical; GO:0090304 nucleic acid metabolic process; GO:0032940 secretion by cell; GO:0050856 regulation of T cell receptor signaling pathway; GO:2001236 regulation of extrinsic apoptotic signaling pathway; GO:0043299 leukocyte degranulation; GO:0040011 locomotion; GO:0006952 defense response; GO:0048856 anatomical structure development; GO:0050868 negative regulation of T cell activation; GO:0016477 cell migration; GO:0070228 regulation of lymphocyte apoptotic process; GO:0043069 negative regulation of programmed cell death; GO:0051250 negative regulation of lymphocyte activation; GO:0006725 cellular aromatic compound metabolic process; GO:0002252 immune effector process; GO:0050896 response to stimulus; GO:0045087 innate immune response; GO:0071704 organic substance metabolic process; GO:0048245 eosinophil chemotaxis; GO:0050854 regulation of antigen receptor-mediated signaling pathway; GO:0030154 cell differentiation; GO:0043066 negative regulation of apoptotic process; GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors; GO:0034641 cellular nitrogen compound metabolic process; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0050918 positive chemotaxis; GO:2000520 regulation of immunological synapse formation; GO:0051049 regulation of transport; GO:0090279 regulation of calcium ion import; GO:0006807 nitrogen compound metabolic process; GO:0042129 regulation of T cell proliferation; GO:0048585 negative regulation of response to stimulus; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0022407 regulation of cell-cell adhesion; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:2000106 regulation of leukocyte apoptotic process; GO:0030595 leukocyte chemotaxis; GO:0072677 eosinophil migration; GO:0044767 single-organism developmental process; GO:0002684 positive regulation of immune system process; GO:0010467 gene expression; GO:0051128 regulation of cellular component organization; GO:0040012 regulation of locomotion; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0099503 secretory vesicle; GO:0019866 organelle inner membrane; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0044429 mitochondrial part; GO:0070820 tertiary granule; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0005681 spliceosomal complex; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0030667 secretory granule membrane; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0101003 ficolin-1-rich granule membrane; GO:0031975 envelope; GO:0001772 immunological synapse; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043230 extracellular organelle; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0019865 immunoglobulin binding; GO:0043236 laminin binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0044877 macromolecular complex binding; GO:0030246 carbohydrate binding; GO:0005515 protein binding; GO:0050840 extracellular matrix binding; GO:0042056 chemoattractant activity; GO:0032403 protein complex binding; GO:0019863 IgE binding; ","K06831",null,null,"IPR001079; IPR013320; ","\"Galectin, carbohydrate recognition domain; Concanavalin A-like lectin/glucanase domain; \"\r"]
["P17980","26S proteasome regulatory subunit 6A OS=Homo sapiens OX=9606 GN=PSMC3","PSMC3",49.203,106.7,44.4,17,33,17,0.947,0.933,0.947,1.02,1.052,1.088,1.118,0.00452,"cytoplasm\r",{"$cut":{"chars":17132,"head":"GO:0044700 single organism signaling; GO:0010608 posttranscriptional regulation of gene expression; GO:0043009 chordate embryonic development; GO:0051443 positive regulation of ubiquitin-protein transferase activity; GO:0009891 positive regulation of biosynthetic process; GO:0031347 regulation of defense response; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:1903364 positive regulation of cellular protein catabolic process; GO:0008152 metabolic process; GO:0044093 positive regulation of molecular function; GO:0090263 positive regulation of canonical Wnt signaling pathway; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0016055 Wnt signaling pathway; GO:0009790 embryo development; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0006521 regulation of cellular amino acid metabolic process; GO:0080090 regulation of primary metabolic process; GO:0010972 negative regulation of G2/M transition of mitotic cell cycle; GO:0044763 single-organism cellular process; GO:0060828 regulation of canonical Wnt signaling pathway; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0043086 negative regulation of catalytic activity; GO:0033209 tumor necrosis factor-mediated signaling pathway; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0000165 MAPK cascade; GO:0019884 antigen processing and presentation of exogenous antigen; GO:1901575 organic substance catabolic process; GO:0007267 cell-cell signaling; GO:0002223 stimulatory C-type lectin receptor signaling pathway; GO:0030163 protein catabolic process; GO:0061136 regulation of proteasomal protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0060071 Wnt signaling pathway, planar cell polarity pathway; GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0016310 phosphorylation; GO:0044707 single-multicellular organism process; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0043487 regulation of RNA stability; GO:0000209 protein polyubiquitination; GO:0023057 negative regulation of signaling; GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly; GO:0010648 negative regulation of cell communication; GO:0009889 regulation of biosynthetic process; GO:0009896 positive regulation of catabolic process; GO:0043620 regulation of DNA-templated transcription in response to stress; GO:0070482 response to oxygen levels; GO:0044248 cellular catabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0042176 regulation of protein catabolic process; GO:0038093 Fc receptor signaling pathway; GO:0050778 positive regulation of immune response; GO:0023014 signal transduction by protein phosphorylation; GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; GO:0006950 response to stress; GO:0016567 protein ubiquitination; GO:2000142 regulation of DNA-templated transcription, initiation; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0002263 cell activation involved in immune response; GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:1903321 negative regulation of protein modification by small protein conjugation or removal; GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter; GO:0045055 regulated exocytosis; GO:0009890 negative regulation of biosynthetic process; GO:0031398 positive regulation of protein ubiquitina"}},"GO:0016020 membrane; GO:0034774 secretory granule lumen; GO:0031410 cytoplasmic vesicle; GO:0005838 proteasome regulatory particle; GO:0000932 P-body; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0044422 organelle part; GO:1905369 endopeptidase complex; GO:0043228 non-membrane-bounded organelle; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0022624 proteasome accessory complex; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0044445 cytosolic part; GO:0030141 secretory granule; GO:1905368 peptidase complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0000502 proteasome complex; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0031595 nuclear proteasome complex; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0008540 proteasome regulatory particle, base subcomplex; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0031597 cytosolic proteasome complex; GO:0035770 ribonucleoprotein granule; GO:1990904 ribonucleoprotein complex; GO:0043234 protein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0016887 ATPase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0042802 identical protein binding; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003714 transcription corepressor activity; GO:0005524 ATP binding; GO:0036402 proteasome-activating ATPase activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0003712 transcription cofactor activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0042623 ATPase activity, coupled; GO:0003713 transcription coactivator activity; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0017025 TBP-class protein binding; GO:0000988 transcription factor activity, protein binding; GO:0008134 transcription factor binding; GO:0036094 small molecule binding; ","K03065","PSMC3; 26S proteasome regulatory subunit T5","hsa03050 Proteasome - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); ","IPR003593; IPR003959; IPR027417; ","\"AAA+ ATPase domain; ATPase, AAA-type, core; P-loop containing nucleoside triphosphate hydrolase; \"\r"]
["P17987","T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1","TCP1",60.343,83.517,30.4,17,23,17,0.904,0.917,0.934,1.108,1.063,1.079,1.18,0.000423,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0010941 regulation of cell death; GO:0035036 sperm-egg recognition; GO:0022414 reproductive process; GO:0007021 tubulin complex assembly; GO:0051973 positive regulation of telomerase activity; GO:0009891 positive regulation of biosynthetic process; GO:1904816 positive regulation of protein localization to chromosome, telomeric region; GO:0032204 regulation of telomere maintenance; GO:0015031 protein transport; GO:1904851 positive regulation of establishment of protein localization to telomere; GO:0006458 'de novo' protein folding; GO:0032879 regulation of localization; GO:0065003 macromolecular complex assembly; GO:0044702 single organism reproductive process; GO:0044417 translocation of molecules into host; GO:0044093 positive regulation of molecular function; GO:1904874 positive regulation of telomerase RNA localization to Cajal body; GO:0044053 translocation of peptides or proteins into host cell cytoplasm; GO:0051347 positive regulation of transferase activity; GO:0008104 protein localization; GO:0044419 interspecies interaction between organisms; GO:0051054 positive regulation of DNA metabolic process; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0019953 sexual reproduction; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0031323 regulation of cellular metabolic process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0090666 scaRNA localization to Cajal body; GO:0050790 regulation of catalytic activity; GO:2001252 positive regulation of chromosome organization; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0000003 reproduction; GO:0050794 regulation of cellular process; GO:0043067 regulation of programmed cell death; GO:0009988 cell-cell recognition; GO:0032844 regulation of homeostatic process; GO:0051808 translocation of peptides or proteins into other organism involved in symbiotic interaction; GO:0060341 regulation of cellular localization; GO:1904356 regulation of telomere maintenance via telomere lengthening; GO:0009889 regulation of biosynthetic process; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0032880 regulation of protein localization; GO:1904872 regulation of telomerase RNA localization to Cajal body; GO:0006461 protein complex assembly; GO:1904869 regulation of protein localization to Cajal body; GO:0006403 RNA localization; GO:1904814 regulation of protein localization to chromosome, telomeric region; GO:0071702 organic substance transport; GO:2000278 regulation of DNA biosynthetic process; GO:0033044 regulation of chromosome organization; GO:0044766 multi-organism transport; GO:0045184 establishment of protein localization; GO:1900182 positive regulation of protein localization to nucleus; GO:1904951 positive regulation of establishment of protein localization; GO:0032206 positive regulation of telomere maintenance; GO:0031325 positive regulation of cellular metabolic process; GO:0051972 regulation of telomerase activity; GO:0031647 regulation of protein stability; GO:0031328 positive regulation of cellular biosynthetic process; GO:0051179 localization; GO:0050821 protein stabilization; GO:0090670 RNA localization to Cajal body; GO:1903827 regulation of cellular protein localization; GO:0061077 chaperone-mediated protein folding; GO:0044699 single-organism process; GO:0033032 regulation of myeloid cell apoptotic process; GO:1901998 toxin transport; GO:0051234 establishment of localization; GO:0006457 protein folding; GO:0051130 positive regulation of cellular component organization; GO:0009893 positive regulation of metabolic process; GO:0022607 cellular component assembly; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:2000109 regulation of macrophage apoptotic process; GO:0032846 positive regulation of homeostatic process; GO:0033036 macromolecule localization; GO:0071822 protein complex subunit organization; GO:0031326 regulation of cellular biosynthetic process; GO:0007339 binding of sperm to zona pellucida; GO:0048522 positive regulation of cellular process; GO:0032212 positive regulation of telomere maintenance via telomerase; GO:0009566 fertilization; GO:0050789 regulation of biological process; GO:0051052 regulation of DNA metabolic process; GO:0010638 positive regulation of organelle organization; GO:1900180 regulation of protein localization to nucleus; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0070202 regulation of establishment of protein localization to chromosome; GO:0070271 protein complex biogenesis; GO:0016043 cellular component organization; GO:1902579 multi-organism localization; GO:0032210 regulation of telomere maintenance via telomerase; GO:1903829 positive regulation of cellular protein localization; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0008037 cell recognition; GO:0070201 regulation of establishment of protein localization; GO:0051836 translocation of molecules into other organism involved in symbiotic interaction; GO:1904871 positive regulation of protein localization to Cajal body; GO:0009987 cellular process; GO:0043623 cellular protein complex assembly; GO:0042000 translocation of peptides or proteins into host; GO:0034622 cellular macromolecular complex assembly; GO:1904358 positive regulation of telomere maintenance via telomere lengthening; GO:0033043 regulation of organelle organization; GO:0010556 regulation of macromolecule biosynthetic process; GO:0051701 interaction with host; GO:0007338 single fertilization; GO:0048518 positive regulation of biological process; GO:0043933 macromolecular complex subunit organization; GO:0043085 positive regulation of catalytic activity; GO:2000106 regulation of leukocyte apoptotic process; GO:0070203 regulation of establishment of protein localization to telomere; GO:0044703 multi-organism reproductive process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0051128 regulation of cellular component organization; GO:2000573 positive regulation of DNA biosynthetic process; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0044421 extracellular region part; GO:0044450 microtubule organizing center part; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0005623 cell; GO:0099080 supramolecular complex; GO:0000792 heterochromatin; GO:0044422 organelle part; GO:0002199 zona pellucida receptor complex; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0044454 nuclear chromosome part; GO:0043209 myelin sheath; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0000790 nuclear chromatin; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0099513 polymeric cytoskeletal fiber; GO:0044430 cytoskeletal part; GO:0005832 chaperonin-containing T-complex; GO:0031981 nuclear lumen; GO:0005576 extracellular region; GO:0099081 supramolecular polymer; GO:0005720 nuclear heterochromatin; GO:0043231 intracellular membrane-bounded organelle; GO:0000785 chromatin; GO:0101031 chaperone complex; GO:0097223 sperm part; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0005874 microtubule; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0099512 supramolecular fiber; GO:0000242 pericentriolar material; GO:0044427 chromosomal part; GO:0005856 cytoskeleton; GO:0031974 membrane-enclosed lumen; GO:0005815 microtubule organizing center; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0044464 cell part; GO:0005694 chromosome; GO:1903561 extracellular vesicle; GO:0044445 cytosolic part; GO:0030141 secretory granule; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0043226 organelle; GO:0005634 nucleus; GO:0005813 centrosome; GO:0001669 acrosomal vesicle; GO:0000228 nuclear chromosome; GO:0044297 cell body; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0003723 RNA binding; GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0031625 ubiquitin protein ligase binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0044183 protein binding involved in protein folding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0003676 nucleic acid binding; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0051082 unfolded protein binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0019899 enzyme binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K09493",null,null,"IPR027410; IPR027409; IPR027413; ","TCP-1-like chaperonin intermediate domain; GroEL-like apical domain; GroEL-like equatorial domain; \r"]
["P18031","Tyrosine-protein phosphatase non-receptor type 1 OS=Homo sapiens OX=9606 GN=PTPN1","PTPN1",49.966,18.764,15.4,7,9,7,0.888,0.867,0.878,1.048,1.116,1.141,1.255,1E-3,"cytoplasm\r","GO:0060627 regulation of vesicle-mediated transport; GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0048008 platelet-derived growth factor receptor signaling pathway; GO:0032872 regulation of stress-activated MAPK cascade; GO:0032270 positive regulation of cellular protein metabolic process; GO:0007166 cell surface receptor signaling pathway; GO:1903894 regulation of IRE1-mediated unfolded protein response; GO:0043506 regulation of JUN kinase activity; GO:0031347 regulation of defense response; GO:1905897 regulation of response to endoplasmic reticulum stress; GO:0044237 cellular metabolic process; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0030036 actin cytoskeleton organization; GO:0008152 metabolic process; GO:0035966 response to topologically incorrect protein; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0009719 response to endogenous stimulus; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0051347 positive regulation of transferase activity; GO:1901652 response to peptide; GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway; GO:1905898 positive regulation of response to endoplasmic reticulum stress; GO:1903898 negative regulation of PERK-mediated unfolded protein response; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0051174 regulation of phosphorus metabolic process; GO:0097696 STAT cascade; GO:0080090 regulation of primary metabolic process; GO:2000646 positive regulation of receptor catabolic process; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0090287 regulation of cellular response to growth factor stimulus; GO:1900102 negative regulation of endoplasmic reticulum unfolded protein response; GO:0031323 regulation of cellular metabolic process; GO:0043086 negative regulation of catalytic activity; GO:0050776 regulation of immune response; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0031532 actin cytoskeleton reorganization; GO:0000165 MAPK cascade; GO:0010243 response to organonitrogen compound; GO:0051336 regulation of hydrolase activity; GO:0080135 regulation of cellular response to stress; GO:1902532 negative regulation of intracellular signal transduction; GO:0032874 positive regulation of stress-activated MAPK cascade; GO:0060759 regulation of response to cytokine stimulus; GO:0044710 single-organism metabolic process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:1901698 response to nitrogen compound; GO:0032869 cellular response to insulin stimulus; GO:0010604 positive regulation of macromolecule metabolic process; GO:0002682 regulation of immune system process; GO:0051223 regulation of protein transport; GO:0006464 cellular protein modification process; GO:0060548 negative regulation of cell death; GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation; GO:0050794 regulation of cellular process; GO:0016310 phosphorylation; GO:1900077 negative regulation of cellular response to insulin stimulus; GO:0033554 cellular response to stress; GO:0007259 JAK-STAT cascade; GO:0043407 negative regulation of MAP kinase activity; GO:0034976 response to endoplasmic reticulum stress; GO:0031399 regulation of protein modification process; GO:0043067 regulation of programmed cell death; GO:0044267 cellular protein metabolic process; GO:1901700 response to oxygen-containing compound; GO:0046627 negative regulation of insulin receptor signaling pathway; GO:0032075 positive regulation of nuclease activity; GO:0080134 regulation of response to stress; GO:0071902 positive regulation of protein serine/threonine kinase activity; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response; GO:0060341 regulation of cellular localization; GO:1900101 regulation of endoplasmic reticulum unfolded protein response; GO:0032069 regulation of nuclease activity; GO:0070372 regulation of ERK1 and ERK2 cascade; GO:0023057 negative regulation of signaling; GO:0032147 activation of protein kinase activity; GO:0061098 positive regulation of protein tyrosine kinase activity; GO:0010648 negative regulation of cell communication; GO:0051345 positive regulation of hydrolase activity; GO:0009896 positive regulation of catabolic process; GO:0070373 negative regulation of ERK1 and ERK2 cascade; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0001933 negative regulation of protein phosphorylation; GO:0032880 regulation of protein localization; GO:0007010 cytoskeleton organization; GO:0035791 platelet-derived growth factor receptor-beta signaling pathway; GO:0009966 regulation of signal transduction; GO:1903896 positive regulation of IRE1-mediated unfolded protein response; GO:0023014 signal transduction by protein phosphorylation; GO:0006986 response to unfolded protein; GO:0030100 regulation of endocytosis; GO:1902531 regulation of intracellular signal transduction; GO:0006950 response to stress; GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1903573 negative regulation of response to endoplasmic reticulum stress; GO:0043406 positive regulation of MAP kinase activity; GO:0051247 positive regulation of protein metabolic process; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0031325 positive regulation of cellular metabolic process; GO:0043409 negative regulation of MAPK cascade; GO:0048584 positive regulation of response to stimulus; GO:0043412 macromolecule modification; GO:1903827 regulation of cellular protein localization; GO:0045936 negative regulation of phosphate metabolic process; GO:0046330 positive regulation of JNK cascade; GO:0008286 insulin receptor signaling pathway; GO:0009968 negative regulation of signal transduction; GO:0031331 positive regulation of cellular catabolic process; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0031400 negative regulation of protein modification process; GO:0030968 endoplasmic reticulum unfolded protein response; GO:0031098 stress-activated protein kinase signaling cascade; GO:0006796 phosphate-containing compound metabolic process; GO:2001233 regulation of apoptotic signaling pathway; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0070302 regulation of stress-activated protein kinase signaling cascade; GO:2001243 negative regulation of intrinsic apoptotic signaling pathway; GO:0007154 cell communication; GO:1901653 cellular response to peptide; GO:0071901 negative regulation of protein serine/threonine kinase activity; GO:0045088 regulation of innate immune response; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0033673 negative regulation of kinase activity; GO:0070304 positive regulation of stress-activated protein kinase signaling cascade; GO:0033674 positive regulation of kinase activity; GO:1903897 regulation of PERK-mediated unfolded protein response; GO:0046328 regulation of JNK cascade; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0070887 cellular response to chemical stimulus; GO:0045937 positive regulation of phosphate metabolic process; GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway; GO:0061097 regulation of protein tyrosine kinase activity; GO:0048522 positive regulation of cellular process; GO:0032386 regulation of intracellular transport; GO:0051348 negative regulation of transferase activity; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway; GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway; GO:0071417 cellular response to organonitrogen compound; GO:1902589 single-organism organelle organization; GO:0042221 response to chemical; GO:0032868 response to insulin; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0043434 response to peptide hormone; GO:1901699 cellular response to nitrogen compound; GO:0043507 positive regulation of JUN kinase activity; GO:0032870 cellular response to hormone stimulus; GO:0007254 JNK cascade; GO:0006469 negative regulation of protein kinase activity; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0071378 cellular response to growth hormone stimulus; GO:0044092 negative regulation of molecular function; GO:0060338 regulation of type I interferon-mediated signaling pathway; GO:0019220 regulation of phosphate metabolic process; GO:0036211 protein modification process; GO:1990264 peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity; GO:0043549 regulation of kinase activity; GO:0045859 regulation of protein kinase activity; GO:0016043 cellular component organization; GO:0043069 negative regulation of programmed cell death; GO:0035967 cellular response to topologically incorrect protein; GO:0050730 regulation of peptidyl-tyrosine phosphorylation; GO:0043405 regulation of MAP kinase activity; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0071310 cellular response to organic substance; GO:0001959 regulation of cytokine-mediated signaling pathway; GO:0060396 growth hormone receptor signaling pathway; GO:1900076 regulation of cellular response to insulin stimulus; GO:0036498 IRE1-mediated unfolded protein response; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0070201 regulation of establishment of protein localization; GO:0071704 organic substance metabolic process; GO:0006468 protein phosphorylation; GO:0043066 negative regulation of apoptotic process; GO:0043408 regulation of MAPK cascade; GO:0023056 positive regulation of signaling; GO:0042326 negative regulation of phosphorylation; GO:0090288 negative regulation of cellular response to growth factor stimulus; GO:0007257 activation of JUN kinase activity; GO:0071375 cellular response to peptide hormone stimulus; GO:1902235 regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway; GO:0010647 positive regulation of cell communication; GO:0033157 regulation of intracellular protein transport; GO:0009987 cellular process; GO:0051403 stress-activated MAPK cascade; GO:0035335 peptidyl-tyrosine dephosphorylation; GO:0034620 cellular response to unfolded protein; GO:0035556 intracellular signal transduction; GO:0051049 regulation of transport; GO:0001932 regulation of protein phosphorylation; GO:0031401 positive regulation of protein modification process; GO:2000644 regulation of receptor catabolic process; GO:0048585 negative regulation of response to stimulus; GO:0060416 response to growth hormone; GO:0006987 activation of signaling protein activity involved in unfolded protein response; GO:0006470 protein dephosphorylation; GO:0001934 positive regulation of protein phosphorylation; GO:0045860 positive regulation of protein kinase activity; GO:0016311 dephosphorylation; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0000187 activation of MAPK activity; GO:1901701 cellular response to oxygen-containing compound; GO:0046626 regulation of insulin receptor signaling pathway; GO:0071495 cellular response to endogenous stimulus; GO:0051246 regulation of protein metabolic process; GO:2001242 regulation of intrinsic apoptotic signaling pathway; GO:0010563 negative regulation of phosphorus metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0051128 regulation of cellular component organization; GO:0009967 positive regulation of signal transduction; GO:0043410 positive regulation of MAPK cascade; GO:0009725 response to hormone; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0098554 cytoplasmic side of endoplasmic reticulum membrane; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0097443 sorting endosome; GO:0005829 cytosol; GO:0005623 cell; GO:0098562 cytoplasmic side of membrane; GO:0044422 organelle part; GO:0005769 early endosome; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044432 endoplasmic reticulum part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; GO:0098552 side of membrane; ","GO:1990782 protein tyrosine kinase binding; GO:0019903 protein phosphatase binding; GO:0005102 receptor binding; GO:0016791 phosphatase activity; GO:0019901 protein kinase binding; GO:0046875 ephrin receptor binding; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0004721 phosphoprotein phosphatase activity; GO:0051721 protein phosphatase 2A binding; GO:0005158 insulin receptor binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0045296 cadherin binding; GO:0043169 cation binding; GO:0019902 phosphatase binding; GO:0003723 RNA binding; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0019900 kinase binding; GO:0008270 zinc ion binding; GO:0050839 cell adhesion molecule binding; GO:0030971 receptor tyrosine kinase binding; GO:0046914 transition metal ion binding; GO:0004725 protein tyrosine phosphatase activity; GO:0042578 phosphoric ester hydrolase activity; GO:0016788 hydrolase activity, acting on ester bonds; GO:0003676 nucleic acid binding; GO:0046872 metal ion binding; GO:0019899 enzyme binding; GO:0032403 protein complex binding; ","K05696","PTPN1; tyrosine-protein phosphatase non-receptor type 1 [EC:3.1.3.48]","hsa04520 Adherens junction - Homo sapiens (human); hsa04910 Insulin signaling pathway - Homo sapiens (human); hsa04931 Insulin resistance - Homo sapiens (human); ","IPR029021; IPR000387; IPR003595; IPR000242; ","\"Protein-tyrosine phosphatase-like; Tyrosine specific protein phosphatases domain; Protein-tyrosine phosphatase, catalytic; PTP type protein phosphatase; \"\r"]
["P18077","60S ribosomal protein L35a OS=Homo sapiens OX=9606 GN=RPL35A","RPL35A",12.538,12.536,40,6,10,6,0.947,0.898,0.854,1.119,1.066,1.118,1.224,0.00392,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0072594 establishment of protein localization to organelle; GO:0006518 peptide metabolic process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0042273 ribosomal large subunit biogenesis; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0051649 establishment of localization in cell; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0070972 protein localization to endoplasmic reticulum; GO:0006364 rRNA processing; GO:0006413 translational initiation; GO:1901361 organic cyclic compound catabolic process; GO:0033365 protein localization to organelle; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0006412 translation; GO:0016072 rRNA metabolic process; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0072657 protein localization to membrane; GO:0043043 peptide biosynthetic process; GO:0042254 ribosome biogenesis; GO:1901360 organic cyclic compound metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032774 RNA biosynthetic process; GO:0045047 protein targeting to ER; GO:0043603 cellular amide metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0006401 RNA catabolic process; GO:0016070 RNA metabolic process; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0019083 viral transcription; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0046907 intracellular transport; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0044267 cellular protein metabolic process; GO:0006613 cotranslational protein targeting to membrane; GO:0048519 negative regulation of biological process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0016032 viral process; GO:0019080 viral gene expression; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0006886 intracellular protein transport; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0034613 cellular protein localization; GO:0009059 macromolecule biosynthetic process; GO:0090150 establishment of protein localization to membrane; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0051179 localization; GO:0009056 catabolic process; GO:0034660 ncRNA metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0071840 cellular component organization or biogenesis; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0044391 ribosomal subunit; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0044445 cytosolic part; GO:0043227 membrane-bounded organelle; GO:0022626 cytosolic ribosome; GO:0043229 intracellular organelle; GO:0005840 ribosome; GO:0043232 intracellular non-membrane-bounded organelle; GO:0022625 cytosolic large ribosomal subunit; GO:0044446 intracellular organelle part; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0031012 extracellular matrix; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0015934 large ribosomal subunit; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0000049 tRNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0005198 structural molecule activity; GO:0003735 structural constituent of ribosome; ","K02917","RP-L35Ae; large subunit ribosomal protein L35Ae","hsa03010 Ribosome - Homo sapiens (human); ","IPR009000; ","\"Translation protein, beta-barrel domain; \"\r"]
["P18084","Integrin beta-5 OS=Homo sapiens OX=9606 GN=ITGB5","ITGB5",88.053,29.99,8.3,6,7,6,1.051,1.082,1.057,0.982,0.914,0.93,0.886,0.00652,"extracellular\r","GO:0044085 cellular component biogenesis; GO:0044409 entry into host; GO:0044700 single organism signaling; GO:0003012 muscle system process; GO:0007166 cell surface receptor signaling pathway; GO:0048869 cellular developmental process; GO:0071560 cellular response to transforming growth factor beta stimulus; GO:0030038 contractile actin filament bundle assembly; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0071363 cellular response to growth factor stimulus; GO:0007492 endoderm development; GO:0022610 biological adhesion; GO:0030036 actin cytoskeleton organization; GO:0016337 single organismal cell-cell adhesion; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I; GO:0007160 cell-matrix adhesion; GO:0007155 cell adhesion; GO:0009719 response to endogenous stimulus; GO:0070848 response to growth factor; GO:0030198 extracellular matrix organization; GO:0044419 interspecies interaction between organisms; GO:0009790 embryo development; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0070887 cellular response to chemical stimulus; GO:0048598 embryonic morphogenesis; GO:0046718 viral entry into host cell; GO:0032502 developmental process; GO:0031032 actomyosin structure organization; GO:0051716 cellular response to stimulus; GO:0009888 tissue development; GO:0001704 formation of primary germ layer; GO:0048002 antigen processing and presentation of peptide antigen; GO:0098609 cell-cell adhesion; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0007229 integrin-mediated signaling pathway; GO:0023052 signaling; GO:0071559 response to transforming growth factor beta; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:1902589 single-organism organelle organization; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0030260 entry into host cell; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0051828 entry into other organism involved in symbiotic interaction; GO:0098602 single organism cell adhesion; GO:0097435 supramolecular fiber organization; GO:0048856 anatomical structure development; GO:0043149 stress fiber assembly; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0051806 entry into cell of other organism involved in symbiotic interaction; GO:0019058 viral life cycle; GO:0071310 cellular response to organic substance; GO:0007015 actin filament organization; GO:0051017 actin filament bundle assembly; GO:0050896 response to stimulus; GO:0007369 gastrulation; GO:0090136 epithelial cell-cell adhesion; GO:0009653 anatomical structure morphogenesis; GO:0030154 cell differentiation; GO:0006936 muscle contraction; GO:0043062 extracellular structure organization; GO:0016032 viral process; GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0003008 system process; GO:0001706 endoderm formation; GO:0035987 endodermal cell differentiation; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:0007179 transforming growth factor beta receptor signaling pathway; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0051701 interaction with host; GO:0061572 actin filament bundle organization; GO:0019882 antigen processing and presentation; GO:0031589 cell-substrate adhesion; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0071495 cellular response to endogenous stimulus; GO:0030029 actin filament-based process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0098636 protein complex involved in cell adhesion; GO:0031410 cytoplasmic vesicle; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030055 cell-substrate junction; GO:0030139 endocytic vesicle; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0031226 intrinsic component of plasma membrane; GO:0098802 plasma membrane receptor complex; GO:0098797 plasma membrane protein complex; GO:0070161 anchoring junction; GO:0043235 receptor complex; GO:0045335 phagocytic vesicle; GO:0008305 integrin complex; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0034684 integrin alphav-beta5 complex; GO:0009986 cell surface; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0060089 molecular transducer activity; GO:0005515 protein binding; GO:0004872 receptor activity; GO:0001618 virus receptor activity; GO:0005488 binding; ","K06588","ITGB5; integrin beta 5","hsa05414 Dilated cardiomyopathy (DCM) - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); hsa04512 ECM-receptor interaction - Homo sapiens (human); hsa05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human); hsa05410 Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human); ","IPR032695; IPR033760; IPR002369; IPR016201; IPR012896; IPR014836; IPR002035; ","\"Integrin domain; Integrin beta N-terminal; Integrin beta subunit, VWA domain; PSI domain; Integrin beta subunit, tail; Integrin beta subunit, cytoplasmic domain; von Willebrand factor, type A; \"\r"]
["P18085","ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4","ARF4",20.511,16.44,30,5,17,4,1.044,1.06,0.995,0.972,0.962,0.947,0.93,0.024,"cytoplasm\r","GO:0044700 single organism signaling; GO:0043413 macromolecule glycosylation; GO:0010941 regulation of cell death; GO:0007166 cell surface receptor signaling pathway; GO:0007420 brain development; GO:0035088 establishment or maintenance of apical/basal cell polarity; GO:0009891 positive regulation of biosynthetic process; GO:0044237 cellular metabolic process; GO:0050877 neurological system process; GO:0015031 protein transport; GO:0007610 behavior; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0031584 activation of phospholipase D activity; GO:0044093 positive regulation of molecular function; GO:0038127 ERBB signaling pathway; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0033365 protein localization to organelle; GO:0008104 protein localization; GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity; GO:0007399 nervous system development; GO:0006486 protein glycosylation; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0045176 apical protein localization; GO:0045893 positive regulation of transcription, DNA-templated; GO:0060191 regulation of lipase activity; GO:0044763 single-organism cellular process; GO:0009100 glycoprotein metabolic process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0007264 small GTPase mediated signal transduction; GO:0007163 establishment or maintenance of cell polarity; GO:0048870 cell motility; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0006471 protein ADP-ribosylation; GO:0006810 transport; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0051336 regulation of hydrolase activity; GO:0007612 learning; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0007417 central nervous system development; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0060548 negative regulation of cell death; GO:0044708 single-organism behavior; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0044707 single-multicellular organism process; GO:0061512 protein localization to cilium; GO:0044267 cellular protein metabolic process; GO:0043067 regulation of programmed cell death; GO:0010517 regulation of phospholipase activity; GO:0007173 epidermal growth factor receptor signaling pathway; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0051345 positive regulation of hydrolase activity; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:1901135 carbohydrate derivative metabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0010518 positive regulation of phospholipase activity; GO:0007275 multicellular organism development; GO:0061245 establishment or maintenance of bipolar cell polarity; GO:0034613 cellular protein localization; GO:0051254 positive regulation of RNA metabolic process; GO:0006950 response to stress; GO:0043547 positive regulation of GTPase activity; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0045184 establishment of protein localization; GO:0030182 neuron differentiation; GO:0048678 response to axon injury; GO:0060996 dendritic spine development; GO:0031325 positive regulation of cellular metabolic process; GO:0006928 movement of cell or subcellular component; GO:0043412 macromolecule modification; GO:0031328 positive regulation of cellular biosynthetic process; GO:0051179 localization; GO:0051674 localization of cell; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0051234 establishment of localization; GO:0009611 response to wounding; GO:2001141 regulation of RNA biosynthetic process; GO:0008105 asymmetric protein localization; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0060322 head development; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0033036 macromolecule localization; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0009101 glycoprotein biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0060193 positive regulation of lipase activity; GO:0050789 regulation of biological process; GO:0030030 cell projection organization; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0043087 regulation of GTPase activity; GO:0040011 locomotion; GO:0036211 protein modification process; GO:2000377 regulation of reactive oxygen species metabolic process; GO:0048856 anatomical structure development; GO:0016043 cellular component organization; GO:0016477 cell migration; GO:0016358 dendrite development; GO:0043069 negative regulation of programmed cell death; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0048193 Golgi vesicle transport; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0043066 negative regulation of apoptotic process; GO:0050890 cognition; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0070085 glycosylation; GO:0003008 system process; GO:0006355 regulation of transcription, DNA-templated; GO:0035556 intracellular signal transduction; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0031175 neuron projection development; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0007611 learning or memory; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0043085 positive regulation of catalytic activity; GO:0070727 cellular macromolecule localization; GO:0034645 cellular macromolecule biosynthetic process; GO:0006890 retrograde vesicle-mediated transport, Golgi to ER; GO:0044767 single-organism developmental process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0030425 dendrite; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0032587 ruffle membrane; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0043197 dendritic spine; GO:0070062 extracellular exosome; GO:0044309 neuron spine; GO:0098590 plasma membrane region; GO:0031256 leading edge membrane; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0044456 synapse part; GO:0043229 intracellular organelle; GO:0031252 cell leading edge; GO:0042995 cell projection; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0045202 synapse; GO:0043231 intracellular membrane-bounded organelle; GO:0031012 extracellular matrix; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0044459 plasma membrane part; GO:0098794 postsynapse; GO:0001726 ruffle; GO:0031253 cell projection membrane; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0005102 receptor binding; GO:0005086 ARF guanyl-nucleotide exchange factor activity; GO:0005085 guanyl-nucleotide exchange factor activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0003924 GTPase activity; GO:0043168 anion binding; GO:0019001 guanyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0070851 growth factor receptor binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0005154 epidermal growth factor receptor binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0032561 guanyl ribonucleotide binding; GO:0036094 small molecule binding; ","K07939",null,null,"IPR005225; IPR027417; ","Small GTP-binding protein domain; P-loop containing nucleoside triphosphate hydrolase; \r"]
["P18124","60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7","RPL7",29.225,73.651,41.1,12,29,12,0.888,0.913,0.917,1.111,1.126,1.07,1.217,0.000425,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0072594 establishment of protein localization to organelle; GO:0006518 peptide metabolic process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0042273 ribosomal large subunit biogenesis; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0051649 establishment of localization in cell; GO:0002181 cytoplasmic translation; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0070972 protein localization to endoplasmic reticulum; GO:0006364 rRNA processing; GO:0000470 maturation of LSU-rRNA; GO:0006413 translational initiation; GO:1901361 organic cyclic compound catabolic process; GO:0033365 protein localization to organelle; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0006412 translation; GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); GO:0016072 rRNA metabolic process; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0072657 protein localization to membrane; GO:0043043 peptide biosynthetic process; GO:0042254 ribosome biogenesis; GO:1901360 organic cyclic compound metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032774 RNA biosynthetic process; GO:0045047 protein targeting to ER; GO:0043603 cellular amide metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0006401 RNA catabolic process; GO:0016070 RNA metabolic process; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0019083 viral transcription; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0046907 intracellular transport; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0044267 cellular protein metabolic process; GO:0006613 cotranslational protein targeting to membrane; GO:0048519 negative regulation of biological process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0016032 viral process; GO:0019080 viral gene expression; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0006886 intracellular protein transport; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0034613 cellular protein localization; GO:0009059 macromolecule biosynthetic process; GO:0090150 establishment of protein localization to membrane; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0051179 localization; GO:0034660 ncRNA metabolic process; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0005925 focal adhesion; GO:0070013 intracellular organelle lumen; GO:0044391 ribosomal subunit; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030055 cell-substrate junction; GO:0044445 cytosolic part; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0022626 cytosolic ribosome; GO:0043229 intracellular organelle; GO:0005840 ribosome; GO:0043232 intracellular non-membrane-bounded organelle; GO:0022625 cytosolic large ribosomal subunit; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0015934 large ribosomal subunit; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0005844 polysome; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003729 mRNA binding; GO:0003677 DNA binding; GO:0003723 RNA binding; GO:0042802 identical protein binding; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0046983 protein dimerization activity; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0005198 structural molecule activity; GO:0003735 structural constituent of ribosome; ","K02937","RP-L7e; large subunit ribosomal protein L7e","hsa03010 Ribosome - Homo sapiens (human); ","IPR012988; IPR016082; ","\"Ribosomal protein L30, N-terminal; Ribosomal protein L30, ferredoxin-like fold domain; \"\r"]
["P18206","Vinculin OS=Homo sapiens OX=9606 GN=VCL","VCL",123.8,323.31,61.6,69,165,69,1.092,1.092,1.115,0.907,0.915,0.893,0.823,4e-05,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0097581 lamellipodium organization; GO:0065008 regulation of biological quality; GO:0007596 blood coagulation; GO:0003012 muscle system process; GO:0045321 leukocyte activation; GO:0048869 cellular developmental process; GO:0048666 neuron development; GO:0045216 cell-cell junction organization; GO:0032989 cellular component morphogenesis; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0051234 establishment of localization; GO:0009611 response to wounding; GO:0040013 negative regulation of locomotion; GO:0022610 biological adhesion; GO:0016337 single organismal cell-cell adhesion; GO:0048729 tissue morphogenesis; GO:0032990 cell part morphogenesis; GO:0022607 cellular component assembly; GO:0032879 regulation of localization; GO:0007160 cell-matrix adhesion; GO:0034332 adherens junction organization; GO:0048858 cell projection morphogenesis; GO:0007155 cell adhesion; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0007399 nervous system development; GO:0030032 lamellipodium assembly; GO:0032502 developmental process; GO:0048675 axon extension; GO:0060429 epithelium development; GO:0002443 leukocyte mediated immunity; GO:0009888 tissue development; GO:0030168 platelet activation; GO:0048699 generation of neurons; GO:0016049 cell growth; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0098609 cell-cell adhesion; GO:0048812 neuron projection morphogenesis; GO:2000146 negative regulation of cell motility; GO:0032501 multicellular organismal process; GO:0002444 myeloid leukocyte mediated immunity; GO:0000902 cell morphogenesis; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0030030 cell projection organization; GO:0032940 secretion by cell; GO:0098602 single organism cell adhesion; GO:0034333 adherens junction assembly; GO:0050817 coagulation; GO:0043299 leukocyte degranulation; GO:0048856 anatomical structure development; GO:0070527 platelet aggregation; GO:0051271 negative regulation of cellular component movement; GO:0050794 regulation of cellular process; GO:0002009 morphogenesis of an epithelium; GO:0034329 cell junction assembly; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0002576 platelet degranulation; GO:1990138 neuron projection extension; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:0034109 homotypic cell-cell adhesion; GO:0007599 hemostasis; GO:0048468 cell development; GO:0000904 cell morphogenesis involved in differentiation; GO:0090136 epithelial cell-cell adhesion; GO:0009653 anatomical structure morphogenesis; GO:0030154 cell differentiation; GO:0006936 muscle contraction; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:2000145 regulation of cell motility; GO:0007409 axonogenesis; GO:0036230 granulocyte activation; GO:0007275 multicellular organism development; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0034394 protein localization to cell surface; GO:0043297 apical junction assembly; GO:0007043 cell-cell junction assembly; GO:0050878 regulation of body fluid levels; GO:0003008 system process; GO:0006950 response to stress; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0060560 developmental growth involved in morphogenesis; GO:0002376 immune system process; GO:0030334 regulation of cell migration; GO:0043312 neutrophil degranulation; GO:0031175 neuron projection development; GO:0002263 cell activation involved in immune response; GO:0030031 cell projection assembly; GO:0051641 cellular localization; GO:0002366 leukocyte activation involved in immune response; GO:0030182 neuron differentiation; GO:0061564 axon development; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0070727 cellular macromolecule localization; GO:0042060 wound healing; GO:0034330 cell junction organization; GO:0030336 negative regulation of cell migration; GO:0031589 cell-substrate adhesion; GO:0048588 developmental cell growth; GO:0044767 single-organism developmental process; GO:0006928 movement of cell or subcellular component; GO:0001775 cell activation; GO:0006955 immune response; GO:0040012 regulation of locomotion; GO:0048589 developmental growth; GO:0051179 localization; GO:0040007 growth; GO:0065007 biological regulation; GO:0006887 exocytosis; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0098862 cluster of actin-based cell projections; GO:0098857 membrane microdomain; GO:1990357 terminal web; GO:0099568 cytoplasmic region; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0005913 cell-cell adherens junction; GO:0099080 supramolecular complex; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0014704 intercalated disc; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0098589 membrane region; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0044430 cytoskeletal part; GO:0090637 inner dense plaque of desmosome; GO:0070161 anchoring junction; GO:0005576 extracellular region; GO:0099081 supramolecular polymer; GO:0005886 plasma membrane; GO:0090636 outer dense plaque of desmosome; GO:0030057 desmosome; GO:0043034 costamere; GO:0005915 zonula adherens; GO:0044449 contractile fiber part; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0034774 secretory granule lumen; GO:0005903 brush border; GO:0005938 cell cortex; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0044291 cell-cell contact zone; GO:0030016 myofibril; GO:0031982 vesicle; GO:0030863 cortical cytoskeleton; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0030864 cortical actin cytoskeleton; GO:0005911 cell-cell junction; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0043292 contractile fiber; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0005916 fascia adherens; GO:0030141 secretory granule; GO:0045121 membrane raft; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0002102 podosome; GO:0015629 actin cytoskeleton; GO:0043296 apical junction complex; GO:0043226 organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0035580 specific granule lumen; GO:0044448 cell cortex part; GO:0042581 specific granule; GO:0044444 cytoplasmic part; ","GO:0051015 actin filament binding; GO:0031625 ubiquitin protein ligase binding; GO:0002162 dystroglycan binding; GO:0044877 macromolecular complex binding; GO:0005515 protein binding; GO:0045294 alpha-catenin binding; GO:0050839 cell adhesion molecule binding; GO:0097367 carbohydrate derivative binding; GO:0008092 cytoskeletal protein binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0003779 actin binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0001948 glycoprotein binding; GO:0005198 structural molecule activity; GO:0019899 enzyme binding; GO:0008013 beta-catenin binding; GO:0032403 protein complex binding; ","K05700","VCL; vinculin","hsa05100 Bacterial invasion of epithelial cells - Homo sapiens (human); hsa04670 Leukocyte transendothelial migration - Homo sapiens (human); hsa04520 Adherens junction - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa05131 Shigellosis - Homo sapiens (human); hsa05146 Amoebiasis - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); "]
["P18405","3-oxo-5-alpha-steroid 4-dehydrogenase 1 OS=Homo sapiens OX=9606 GN=SRD5A1","SRD5A1",29.458,2.7931,5.8,2,2,2,1.225,1.292,1.452,0.56,0.724,0.786,0.522,0.00442,"extracellular\r","GO:0042446 hormone biosynthetic process; GO:0065008 regulation of biological quality; GO:0048732 gland development; GO:0021766 hippocampus development; GO:0022414 reproductive process; GO:0007420 brain development; GO:0008584 male gonad development; GO:0071384 cellular response to corticosteroid stimulus; GO:0046683 response to organophosphorus; GO:0044255 cellular lipid metabolic process; GO:0021987 cerebral cortex development; GO:0044237 cellular metabolic process; GO:0008610 lipid biosynthetic process; GO:0007622 rhythmic behavior; GO:0007610 behavior; GO:0021537 telencephalon development; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0042448 progesterone metabolic process; GO:0071872 cellular response to epinephrine stimulus; GO:0042180 cellular ketone metabolic process; GO:0071549 cellular response to dexamethasone stimulus; GO:0044702 single organism reproductive process; GO:0048545 response to steroid hormone; GO:0009719 response to endogenous stimulus; GO:0070848 response to growth factor; GO:1901652 response to peptide; GO:0007399 nervous system development; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0003006 developmental process involved in reproduction; GO:0071868 cellular response to monoamine stimulus; GO:0006702 androgen biosynthetic process; GO:0044281 small molecule metabolic process; GO:0008202 steroid metabolic process; GO:0044763 single-organism cellular process; GO:0032501 multicellular organismal process; GO:0071396 cellular response to lipid; GO:0034754 cellular hormone metabolic process; GO:0010243 response to organonitrogen compound; GO:0048513 animal organ development; GO:0014823 response to activity; GO:0051591 response to cAMP; GO:0018958 phenol-containing compound metabolic process; GO:0044710 single-organism metabolic process; GO:0007417 central nervous system development; GO:0032869 cellular response to insulin stimulus; GO:1901698 response to nitrogen compound; GO:0010817 regulation of hormone levels; GO:0016101 diterpenoid metabolic process; GO:0030431 sleep; GO:1901362 organic cyclic compound biosynthetic process; GO:0044708 single-organism behavior; GO:0071392 cellular response to estradiol stimulus; GO:0000003 reproduction; GO:0044707 single-multicellular organism process; GO:0033554 cellular response to stress; GO:0009267 cellular response to starvation; GO:1901615 organic hydroxy compound metabolic process; GO:0021854 hypothalamus development; GO:0008406 gonad development; GO:0014850 response to muscle activity; GO:1901700 response to oxygen-containing compound; GO:0097164 ammonium ion metabolic process; GO:0032355 response to estradiol; GO:0021983 pituitary gland development; GO:0022410 circadian sleep/wake cycle process; GO:0021794 thalamus development; GO:0008207 C21-steroid hormone metabolic process; GO:0042493 response to drug; GO:0046483 heterocycle metabolic process; GO:0014074 response to purine-containing compound; GO:0007548 sex differentiation; GO:0061008 hepaticobiliary system development; GO:0030900 forebrain development; GO:0007275 multicellular organism development; GO:0048806 genitalia development; GO:0061458 reproductive system development; GO:0042430 indole-containing compound metabolic process; GO:0050802 circadian sleep/wake cycle, sleep; GO:0006720 isoprenoid metabolic process; GO:1901655 cellular response to ketone; GO:0044711 single-organism biosynthetic process; GO:0071385 cellular response to glucocorticoid stimulus; GO:0006950 response to stress; GO:0048731 system development; GO:0071407 cellular response to organic cyclic compound; GO:0071496 cellular response to external stimulus; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0060992 response to fungicide; GO:0031668 cellular response to extracellular stimulus; GO:0060348 bone development; GO:0006694 steroid biosynthetic process; GO:0001889 liver development; GO:0071870 cellular response to catecholamine stimulus; GO:0046546 development of primary male sexual characteristics; GO:1901564 organonitrogen compound metabolic process; GO:0043627 response to estrogen; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0071363 cellular response to growth factor stimulus; GO:0021761 limbic system development; GO:0046660 female sex differentiation; GO:0071383 cellular response to steroid hormone stimulus; GO:0008209 androgen metabolic process; GO:1901653 cellular response to peptide; GO:0007154 cell communication; GO:0007530 sex determination; GO:0042428 serotonin metabolic process; GO:0060322 head development; GO:0071871 response to epinephrine; GO:0048512 circadian behavior; GO:0070887 cellular response to chemical stimulus; GO:0006629 lipid metabolic process; GO:0032502 developmental process; GO:0042445 hormone metabolic process; GO:0071869 response to catecholamine; GO:0021510 spinal cord development; GO:0055114 oxidation-reduction process; GO:0009636 response to toxic substance; GO:0048608 reproductive structure development; GO:0030539 male genitalia development; GO:1901360 organic cyclic compound metabolic process; GO:0033574 response to testosterone; GO:0051384 response to glucocorticoid; GO:0007623 circadian rhythm; GO:0071417 cellular response to organonitrogen compound; GO:0001655 urogenital system development; GO:0032868 response to insulin; GO:0042221 response to chemical; GO:0043434 response to peptide hormone; GO:1901699 cellular response to nitrogen compound; GO:0021536 diencephalon development; GO:0032870 cellular response to hormone stimulus; GO:0035270 endocrine system development; GO:0048856 anatomical structure development; GO:0001501 skeletal system development; GO:0021543 pallium development; GO:0030540 female genitalia development; GO:0006725 cellular aromatic compound metabolic process; GO:0071310 cellular response to organic substance; GO:0046661 male sex differentiation; GO:0071867 response to monoamine; GO:0050896 response to stimulus; GO:0031669 cellular response to nutrient levels; GO:0071704 organic substance metabolic process; GO:0034698 response to gonadotropin; GO:0033993 response to lipid; GO:0009991 response to extracellular stimulus; GO:0030154 cell differentiation; GO:0071375 cellular response to peptide hormone stimulus; GO:0032354 response to follicle-stimulating hormone; GO:0031960 response to corticosteroid; GO:0042747 circadian sleep/wake cycle, REM sleep; GO:0034641 cellular nitrogen compound metabolic process; GO:0009987 cellular process; GO:0045137 development of primary sexual characteristics; GO:0042745 circadian sleep/wake cycle; GO:0071320 cellular response to cAMP; GO:0006807 nitrogen compound metabolic process; GO:0060416 response to growth hormone; GO:0044249 cellular biosynthetic process; GO:0071548 response to dexamethasone; GO:0071394 cellular response to testosterone stimulus; GO:1901701 cellular response to oxygen-containing compound; GO:0048511 rhythmic process; GO:0044767 single-organism developmental process; GO:0071495 cellular response to endogenous stimulus; GO:0006721 terpenoid metabolic process; GO:0042594 response to starvation; GO:0031667 response to nutrient levels; GO:1901160 primary amino compound metabolic process; GO:0009725 response to hormone; GO:0065007 biological regulation; GO:1901654 response to ketone; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0042995 cell projection; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0043025 neuronal cell body; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0044432 endoplasmic reticulum part; GO:0070852 cell body fiber; GO:0044425 membrane part; GO:0043209 myelin sheath; GO:0005622 intracellular; GO:0044464 cell part; GO:0048471 perinuclear region of cytoplasm; GO:0043005 neuron projection; GO:0044297 cell body; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; GO:0070402 NADPH binding; GO:0043167 ion binding; GO:0033218 amide binding; GO:0000166 nucleotide binding; GO:0048037 cofactor binding; GO:0035671 enone reductase activity; GO:0016491 oxidoreductase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0009055 electron carrier activity; GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors; GO:0016229 steroid dehydrogenase activity; GO:0047751 cholestenone 5-alpha-reductase activity; GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0050661 NADP binding; GO:0043168 anion binding; GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors; GO:0050662 coenzyme binding; GO:0036094 small molecule binding; ","K12343","SRD5A1; 3-oxo-5-alpha-steroid 4-dehydrogenase 1 [EC:1.3.1.22]","hsa00140 Steroid hormone biosynthesis - Homo sapiens (human); ","IPR001104; ","\"3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal; \"\r"]
["P18428","Lipopolysaccharide-binding protein OS=Homo sapiens OX=9606 GN=LBP","LBP",53.383,47.639,13.1,5,10,5,0.973,1.047,0.876,1.022,1.003,1.018,1.051,0.422,"extracellular\r","GO:0044700 single organism signaling; GO:0009593 detection of chemical stimulus; GO:0002694 regulation of leukocyte activation; GO:0030335 positive regulation of cell migration; GO:0045321 leukocyte activation; GO:0042108 positive regulation of cytokine biosynthetic process; GO:0007166 cell surface receptor signaling pathway; GO:0032680 regulation of tumor necrosis factor production; GO:0009891 positive regulation of biosynthetic process; GO:0098542 defense response to other organism; GO:0060263 regulation of respiratory burst; GO:0032760 positive regulation of tumor necrosis factor production; GO:0031347 regulation of defense response; GO:0070391 response to lipoteichoic acid; GO:0009607 response to biotic stimulus; GO:0009605 response to external stimulus; GO:0060267 positive regulation of respiratory burst; GO:0042116 macrophage activation; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0051606 detection of stimulus; GO:0050921 positive regulation of chemotaxis; GO:0015920 lipopolysaccharide transport; GO:0090022 regulation of neutrophil chemotaxis; GO:0044765 single-organism transport; GO:0051716 cellular response to stimulus; GO:0006869 lipid transport; GO:0080090 regulation of primary metabolic process; GO:0002758 innate immune response-activating signal transduction; GO:0050729 positive regulation of inflammatory response; GO:0044763 single-organism cellular process; GO:0051272 positive regulation of cellular component movement; GO:0048870 cell motility; GO:0031323 regulation of cellular metabolic process; GO:0006935 chemotaxis; GO:0071396 cellular response to lipid; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0050900 leukocyte migration; GO:0006953 acute-phase response; GO:0002526 acute inflammatory response; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0071624 positive regulation of granulocyte chemotaxis; GO:0042330 taxis; GO:0002682 regulation of immune system process; GO:0002685 regulation of leukocyte migration; GO:0002687 positive regulation of leukocyte migration; GO:0050794 regulation of cellular process; GO:0032677 regulation of interleukin-8 production; GO:0044144 modulation of growth of symbiont involved in interaction with host; GO:0001819 positive regulation of cytokine production; GO:1901700 response to oxygen-containing compound; GO:2000147 positive regulation of cell motility; GO:0060326 cell chemotaxis; GO:0048519 negative regulation of biological process; GO:0080134 regulation of response to stress; GO:0051239 regulation of multicellular organismal process; GO:0044146 negative regulation of growth of symbiont involved in interaction with host; GO:0050867 positive regulation of cell activation; GO:0031349 positive regulation of defense response; GO:0032490 detection of molecule of bacterial origin; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0009889 regulation of biosynthetic process; GO:2000145 regulation of cell motility; GO:1901264 carbohydrate derivative transport; GO:0009966 regulation of signal transduction; GO:0050778 positive regulation of immune response; GO:0009617 response to bacterium; GO:0002232 leukocyte chemotaxis involved in inflammatory response; GO:0002253 activation of immune response; GO:0006950 response to stress; GO:0051270 regulation of cellular component movement; GO:0032720 negative regulation of tumor necrosis factor production; GO:0032496 response to lipopolysaccharide; GO:0016192 vesicle-mediated transport; GO:0043900 regulation of multi-organism process; GO:0032675 regulation of interleukin-6 production; GO:0002523 leukocyte migration involved in inflammatory response; GO:0034143 regulation of toll-like receptor 4 signaling pathway; GO:0009595 detection of biotic stimulus; GO:1903557 positive regulation of tumor necrosis factor superfamily cytokine production; GO:0030334 regulation of cell migration; GO:0071702 organic substance transport; GO:0010876 lipid localization; GO:0032101 regulation of response to external stimulus; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0002263 cell activation involved in immune response; GO:0002696 positive regulation of leukocyte activation; GO:0051247 positive regulation of protein metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0071219 cellular response to molecule of bacterial origin; GO:0001775 cell activation; GO:0006928 movement of cell or subcellular component; GO:0031328 positive regulation of cellular biosynthetic process; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:0006955 immune response; GO:1903555 regulation of tumor necrosis factor superfamily cytokine production; GO:0042534 regulation of tumor necrosis factor biosynthetic process; GO:0051674 localization of cell; GO:0043030 regulation of macrophage activation; GO:0040017 positive regulation of locomotion; GO:0023051 regulation of signaling; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0098581 detection of external biotic stimulus; GO:0001818 negative regulation of cytokine production; GO:0006909 phagocytosis; GO:0051234 establishment of localization; GO:0044126 regulation of growth of symbiont in host; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0045088 regulation of innate immune response; GO:0032642 regulation of chemokine production; GO:0032103 positive regulation of response to external stimulus; GO:0002221 pattern recognition receptor signaling pathway; GO:1902624 positive regulation of neutrophil migration; GO:0033036 macromolecule localization; GO:0002697 regulation of immune effector process; GO:0070887 cellular response to chemical stimulus; GO:0002274 myeloid leukocyte activation; GO:0034121 regulation of toll-like receptor signaling pathway; GO:0042035 regulation of cytokine biosynthetic process; GO:0045926 negative regulation of growth; GO:0050829 defense response to Gram-negative bacterium; GO:0031326 regulation of cellular biosynthetic process; GO:0060264 regulation of respiratory burst involved in inflammatory response; GO:0002237 response to molecule of bacterial origin; GO:0002688 regulation of leukocyte chemotaxis; GO:0048522 positive regulation of cellular process; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0050830 defense response to Gram-positive bacterium; GO:0008228 opsonization; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0050865 regulation of cell activation; GO:0071223 cellular response to lipoteichoic acid; GO:0002224 toll-like receptor signaling pathway; GO:0006954 inflammatory response; GO:0019222 regulation of metabolic process; GO:0040011 locomotion; GO:0006952 defense response; GO:0032722 positive regulation of chemokine production; GO:0071622 regulation of granulocyte chemotaxis; GO:0016477 cell migration; GO:0002218 activation of innate immune response; GO:0040008 regulation of growth; GO:0071222 cellular response to lipopolysaccharide; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0002252 immune effector process; GO:0034123 positive regulation of toll-like receptor signaling pathway; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0031663 lipopolysaccharide-mediated signaling pathway; GO:0051707 response to other organism; GO:0045087 innate immune response; GO:0033993 response to lipid; GO:0043032 positive regulation of macrophage activation; GO:0002690 positive regulation of leukocyte chemotaxis; GO:0032757 positive regulation of interleukin-8 production; GO:0071216 cellular response to biotic stimulus; GO:0023056 positive regulation of signaling; GO:1903556 negative regulation of tumor necrosis factor superfamily cytokine production; GO:0002757 immune response-activating signal transduction; GO:0060265 positive regulation of respiratory burst involved in inflammatory response; GO:0044130 negative regulation of growth of symbiont in host; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:0034145 positive regulation of toll-like receptor 4 signaling pathway; GO:1902622 regulation of neutrophil migration; GO:0032755 positive regulation of interleukin-6 production; GO:0045089 positive regulation of innate immune response; GO:0042742 defense response to bacterium; GO:0002699 positive regulation of immune effector process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0050920 regulation of chemotaxis; GO:0006897 endocytosis; GO:0002281 macrophage activation involved in immune response; GO:0048518 positive regulation of biological process; GO:0034142 toll-like receptor 4 signaling pathway; GO:0043901 negative regulation of multi-organism process; GO:0002366 leukocyte activation involved in immune response; GO:0090023 positive regulation of neutrophil chemotaxis; GO:1901701 cellular response to oxygen-containing compound; GO:0030595 leukocyte chemotaxis; GO:0051246 regulation of protein metabolic process; GO:0006968 cellular defense response; GO:0002684 positive regulation of immune system process; GO:0042535 positive regulation of tumor necrosis factor biosynthetic process; GO:0050727 regulation of inflammatory response; GO:0001817 regulation of cytokine production; GO:0009967 positive regulation of signal transduction; GO:0040012 regulation of locomotion; GO:0065007 biological regulation; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0009986 cell surface; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:0008289 lipid binding; GO:0001530 lipopolysaccharide binding; GO:0097367 carbohydrate derivative binding; GO:0005515 protein binding; GO:0005102 receptor binding; GO:0070891 lipoteichoic acid binding; GO:0005488 binding; ","K05399","LBP; lipopolysaccharide-binding protein","hsa05132 Salmonella infection - Homo sapiens (human); hsa05152 Tuberculosis - Homo sapiens (human); hsa04620 Toll-like receptor signaling pathway - Homo sapiens (human); hsa04064 NF-kappa B signaling pathway - Homo sapiens (human); ","IPR017943; IPR001124; IPR017942; ","\"Bactericidal permeability-increasing protein, alpha/beta domain; Lipid-binding serum glycoprotein, C-terminal; Lipid-binding serum glycoprotein, N-terminal; \"\r"]
["P18510","Interleukin-1 receptor antagonist protein OS=Homo sapiens OX=9606 GN=IL1RN","IL1RN",20.055,32.098,20.9,5,10,5,0.908,0.901,0.891,1.121,1.074,1.084,1.214,0.000161,"extracellular\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0009914 hormone transport; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0046879 hormone secretion; GO:0008152 metabolic process; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0048545 response to steroid hormone; GO:0009719 response to endogenous stimulus; GO:0009306 protein secretion; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0042886 amide transport; GO:0006629 lipid metabolic process; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0014070 response to organic cyclic compound; GO:0002790 peptide secretion; GO:0044763 single-organism cellular process; GO:0023052 signaling; GO:0051384 response to glucocorticoid; GO:0006810 transport; GO:0030072 peptide hormone secretion; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0006953 acute-phase response; GO:0007267 cell-cell signaling; GO:0034114 regulation of heterotypic cell-cell adhesion; GO:0044710 single-organism metabolic process; GO:0002526 acute inflammatory response; GO:0060759 regulation of response to cytokine stimulus; GO:0032940 secretion by cell; GO:0006954 inflammatory response; GO:0048583 regulation of response to stimulus; GO:0010817 regulation of hormone levels; GO:0006952 defense response; GO:0015833 peptide transport; GO:2000026 regulation of multicellular organismal development; GO:0050794 regulation of cellular process; GO:0007162 negative regulation of cell adhesion; GO:0030073 insulin secretion; GO:0001959 regulation of cytokine-mediated signaling pathway; GO:0022408 negative regulation of cell-cell adhesion; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:0071704 organic substance metabolic process; GO:0001960 negative regulation of cytokine-mediated signaling pathway; GO:0033993 response to lipid; GO:0023057 negative regulation of signaling; GO:0010470 regulation of gastrulation; GO:1902578 single-organism localization; GO:0010648 negative regulation of cell communication; GO:2000660 negative regulation of interleukin-1-mediated signaling pathway; GO:0031960 response to corticosteroid; GO:0034115 negative regulation of heterotypic cell-cell adhesion; GO:0009987 cellular process; GO:0009966 regulation of signal transduction; GO:0070587 regulation of cell-cell adhesion involved in gastrulation; GO:0006950 response to stress; GO:2000659 regulation of interleukin-1-mediated signaling pathway; GO:0002376 immune system process; GO:0071702 organic substance transport; GO:0023061 signal release; GO:0010033 response to organic substance; GO:0048585 negative regulation of response to stimulus; GO:0044238 primary metabolic process; GO:0030155 regulation of cell adhesion; GO:0022407 regulation of cell-cell adhesion; GO:0045184 establishment of protein localization; GO:0060761 negative regulation of response to cytokine stimulus; GO:0045995 regulation of embryonic development; GO:0022603 regulation of anatomical structure morphogenesis; GO:0006955 immune response; GO:0051179 localization; GO:0009725 response to hormone; GO:0050793 regulation of developmental process; GO:0071705 nitrogen compound transport; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0005151 interleukin-1, Type II receptor binding; GO:0019838 growth factor binding; GO:0005102 receptor binding; GO:0019966 interleukin-1 binding; GO:0005126 cytokine receptor binding; GO:0005149 interleukin-1 receptor binding; GO:0045352 interleukin-1 Type I receptor antagonist activity; GO:0070851 growth factor receptor binding; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0005152 interleukin-1 receptor antagonist activity; GO:0048019 receptor antagonist activity; GO:0019955 cytokine binding; GO:0005125 cytokine activity; GO:0045353 interleukin-1 Type II receptor antagonist activity; GO:0030545 receptor regulator activity; GO:0005488 binding; GO:0005150 interleukin-1, Type I receptor binding; GO:0030547 receptor inhibitor activity; ","K05481"]
["P18583","Protein SON OS=Homo sapiens OX=9606 GN=SON","SON",263.83,7.0061,1.3,3,3,3,0.878,1.04,0.97,1.027,0.983,1.105,1.079,0.268,"nucleus\r","GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0010941 regulation of cell death; GO:0043069 negative regulation of programmed cell death; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0043067 regulation of programmed cell death; GO:0044699 single-organism process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0044237 cellular metabolic process; GO:1903047 mitotic cell cycle process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0000910 cytokinesis; GO:0043066 negative regulation of apoptotic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0007010 cytoskeleton organization; GO:0051726 regulation of cell cycle; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0048024 regulation of mRNA splicing, via spliceosome; GO:0006396 RNA processing; GO:0010468 regulation of gene expression; GO:0000278 mitotic cell cycle; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0000281 mitotic cytokinesis; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0050684 regulation of mRNA processing; GO:0031323 regulation of cellular metabolic process; GO:0044238 primary metabolic process; GO:0007017 microtubule-based process; GO:0051252 regulation of RNA metabolic process; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:0043484 regulation of RNA splicing; GO:0000226 microtubule cytoskeleton organization; GO:1903311 regulation of mRNA metabolic process; GO:0050789 regulation of biological process; GO:0061640 cytoskeleton-dependent cytokinesis; GO:0090304 nucleic acid metabolic process; GO:0006996 organelle organization; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0010467 gene expression; GO:0051301 cell division; GO:0022402 cell cycle process; GO:0060548 negative regulation of cell death; GO:0016071 mRNA metabolic process; GO:0042981 regulation of apoptotic process; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031974 membrane-enclosed lumen; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003677 DNA binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0050733 RS domain binding; GO:0019904 protein domain specific binding; GO:0005515 protein binding; ",{"$nulls":3},"IPR017986; IPR014720; IPR015943; IPR000467; ","WD40-repeat-containing domain; Double-stranded RNA-binding domain; WD40/YVTN repeat-like-containing domain; G-patch domain; \r"]
["P18621","60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17","RPL17",21.397,24.479,32.1,5,11,5,0.833,0.835,0.795,1.16,1.183,1.154,1.42,3.9e-05,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0072594 establishment of protein localization to organelle; GO:0006518 peptide metabolic process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0051649 establishment of localization in cell; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0070972 protein localization to endoplasmic reticulum; GO:0006364 rRNA processing; GO:0006413 translational initiation; GO:1901361 organic cyclic compound catabolic process; GO:0033365 protein localization to organelle; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0006412 translation; GO:0016072 rRNA metabolic process; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0072657 protein localization to membrane; GO:0043043 peptide biosynthetic process; GO:0042254 ribosome biogenesis; GO:1901360 organic cyclic compound metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032774 RNA biosynthetic process; GO:0045047 protein targeting to ER; GO:0043603 cellular amide metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0006401 RNA catabolic process; GO:0016070 RNA metabolic process; GO:0019439 aromatic compound catabolic process; GO:1901575 organic substance catabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0019083 viral transcription; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0046907 intracellular transport; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0044267 cellular protein metabolic process; GO:0006613 cotranslational protein targeting to membrane; GO:0048519 negative regulation of biological process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0016032 viral process; GO:0019080 viral gene expression; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0006886 intracellular protein transport; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0034613 cellular protein localization; GO:0009059 macromolecule biosynthetic process; GO:0090150 establishment of protein localization to membrane; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0051179 localization; GO:0009056 catabolic process; GO:0034660 ncRNA metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0005840 ribosome; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0022625 cytosolic large ribosomal subunit; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0015934 large ribosomal subunit; GO:0044391 ribosomal subunit; GO:0005622 intracellular; GO:0044464 cell part; GO:0044445 cytosolic part; GO:1990904 ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0030529 intracellular ribonucleoprotein complex; GO:0044444 cytoplasmic part; GO:0022626 cytosolic ribosome; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0005198 structural molecule activity; GO:0003735 structural constituent of ribosome; ","K02880","RP-L17e; large subunit ribosomal protein L17e","hsa03010 Ribosome - Homo sapiens (human); "]
["P18669","Phosphoglycerate mutase 1 OS=Homo sapiens OX=9606 GN=PGAM1","PGAM1",28.804,134.36,55.1,13,38,13,1.007,0.965,0.985,1.022,1.014,1.042,1.041,0.0525,"cytoplasm\r","GO:0009116 nucleoside metabolic process; GO:0045321 leukocyte activation; GO:0006165 nucleoside diphosphate phosphorylation; GO:0019362 pyridine nucleotide metabolic process; GO:0006096 glycolytic process; GO:0009185 ribonucleoside diphosphate metabolic process; GO:0044237 cellular metabolic process; GO:0006006 glucose metabolic process; GO:0008152 metabolic process; GO:0006094 gluconeogenesis; GO:0006091 generation of precursor metabolites and energy; GO:0032787 monocarboxylic acid metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0042325 regulation of phosphorylation; GO:0002443 leukocyte mediated immunity; GO:0051174 regulation of phosphorus metabolic process; GO:0009179 purine ribonucleoside diphosphate metabolic process; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0061620 glycolytic process through glucose-6-phosphate; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0006732 coenzyme metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0005975 carbohydrate metabolic process; GO:0061718 glucose catabolic process to pyruvate; GO:0006810 transport; GO:1902031 regulation of NADP metabolic process; GO:1901575 organic substance catabolic process; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0019674 NAD metabolic process; GO:0044710 single-organism metabolic process; GO:0009126 purine nucleoside monophosphate metabolic process; GO:0006140 regulation of nucleotide metabolic process; GO:0043436 oxoacid metabolic process; GO:0050794 regulation of cellular process; GO:0016310 phosphorylation; GO:0002283 neutrophil activation involved in immune response; GO:0046496 nicotinamide nucleotide metabolic process; GO:0009259 ribonucleotide metabolic process; GO:0046364 monosaccharide biosynthetic process; GO:0006735 NADH regeneration; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0009119 ribonucleoside metabolic process; GO:0043471 regulation of cellular carbohydrate catabolic process; GO:0044711 single-organism biosynthetic process; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0009141 nucleoside triphosphate metabolic process; GO:0006109 regulation of carbohydrate metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0002263 cell activation involved in immune response; GO:0006163 purine nucleotide metabolic process; GO:0034248 regulation of cellular amide metabolic process; GO:0045055 regulated exocytosis; GO:0006793 phosphorus metabolic process; GO:0045730 respiratory burst; GO:0044283 small molecule biosynthetic process; GO:0001775 cell activation; GO:0019637 organophosphate metabolic process; GO:0019320 hexose catabolic process; GO:0051179 localization; GO:0006955 immune response; GO:0019318 hexose metabolic process; GO:0006887 exocytosis; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0046365 monosaccharide catabolic process; GO:0006757 ATP generation from ADP; GO:0043467 regulation of generation of precursor metabolites and energy; GO:0042278 purine nucleoside metabolic process; GO:0046031 ADP metabolic process; GO:0019319 hexose biosynthetic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0046939 nucleotide phosphorylation; GO:0009135 purine nucleoside diphosphate metabolic process; GO:0072524 pyridine-containing compound metabolic process; GO:0061615 glycolytic process through fructose-6-phosphate; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0051196 regulation of coenzyme metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0002274 myeloid leukocyte activation; GO:0051193 regulation of cofactor metabolic process; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0055114 oxidation-reduction process; GO:0010675 regulation of cellular carbohydrate metabolic process; GO:0043456 regulation of pentose-phosphate shunt; GO:0006110 regulation of glycolytic process; GO:0002446 neutrophil mediated immunity; GO:0043470 regulation of carbohydrate catabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0051186 cofactor metabolic process; GO:0016052 carbohydrate catabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0050789 regulation of biological process; GO:0032940 secretion by cell; GO:0019222 regulation of metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0043299 leukocyte degranulation; GO:0006082 organic acid metabolic process; GO:0016051 carbohydrate biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0006734 NADH metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0009118 regulation of nucleoside metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0061621 canonical glycolysis; GO:0006090 pyruvate metabolic process; GO:0005996 monosaccharide metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0036230 granulocyte activation; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0009132 nucleoside diphosphate metabolic process; GO:0046034 ATP metabolic process; GO:1903578 regulation of ATP metabolic process; GO:0044724 single-organism carbohydrate catabolic process; GO:0044712 single-organism catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044282 small molecule catabolic process; GO:0043312 neutrophil degranulation; GO:1900542 regulation of purine nucleotide metabolic process; GO:0002366 leukocyte activation involved in immune response; GO:0046128 purine ribonucleoside metabolic process; GO:0006007 glucose catabolic process; GO:0043455 regulation of secondary metabolic process; GO:0042119 neutrophil activation; GO:0019752 carboxylic acid metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0009056 catabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0034774 secretory granule lumen; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0043209 myelin sheath; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016853 isomerase activity; GO:0046538 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0019901 protein kinase binding; GO:0016868 intramolecular transferase activity, phosphotransferases; GO:0016787 hydrolase activity; GO:0004619 phosphoglycerate mutase activity; GO:0005515 protein binding; GO:0004082 bisphosphoglycerate mutase activity; GO:0019900 kinase binding; GO:0016866 intramolecular transferase activity; GO:0019899 enzyme binding; ","K01834","PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00260 Glycine, serine and threonine metabolism - Homo sapiens (human); hsa04922 Glucagon signaling pathway - Homo sapiens (human); hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human); hsa01230 Biosynthesis of amino acids - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); hsa05230 Central carbon metabolism in cancer - Homo sapiens (human); "]
["P18754","Regulator of chromosome condensation OS=Homo sapiens OX=9606 GN=RCC1","RCC1",44.969,25.47,4.5,1,1,1,0.937,0.837,0.993,1.111,1.105,1.014,1.167,0.055,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0007346 regulation of mitotic cell cycle; GO:0007067 mitotic nuclear division; GO:0048285 organelle fission; GO:0007051 spindle organization; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:1903047 mitotic cell cycle process; GO:0010564 regulation of cell cycle process; GO:0051783 regulation of nuclear division; GO:0051225 spindle assembly; GO:0022607 cellular component assembly; GO:0070925 organelle assembly; GO:0051345 positive regulation of hydrolase activity; GO:0016032 viral process; GO:0044093 positive regulation of molecular function; GO:0044770 cell cycle phase transition; GO:0007052 mitotic spindle organization; GO:0000082 G1/S transition of mitotic cell cycle; GO:0044419 interspecies interaction between organisms; GO:0007010 cytoskeleton organization; GO:0051726 regulation of cell cycle; GO:0009987 cellular process; GO:0044772 mitotic cell cycle phase transition; GO:0000278 mitotic cell cycle; GO:0007059 chromosome segregation; GO:0044843 cell cycle G1/S phase transition; GO:0043547 positive regulation of GTPase activity; GO:0007088 regulation of mitotic nuclear division; GO:0044763 single-organism cellular process; GO:0033043 regulation of organelle organization; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0007017 microtubule-based process; GO:0051704 multi-organism process; GO:0043085 positive regulation of catalytic activity; GO:0000226 microtubule cytoskeleton organization; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0006996 organelle organization; GO:0043087 regulation of GTPase activity; GO:0065009 regulation of molecular function; GO:0000280 nuclear division; GO:1902850 microtubule cytoskeleton organization involved in mitosis; GO:0051301 cell division; GO:0051128 regulation of cellular component organization; GO:0022402 cell cycle process; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0000793 condensed chromosome; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0031965 nuclear membrane; GO:0070013 intracellular organelle lumen; GO:0044454 nuclear chromosome part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0000790 nuclear chromatin; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005635 nuclear envelope; GO:0043232 intracellular non-membrane-bounded organelle; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0000785 chromatin; GO:0031975 envelope; GO:0000228 nuclear chromosome; GO:0000794 condensed nuclear chromosome; GO:0044428 nuclear part; ","GO:0042393 histone binding; GO:0003677 DNA binding; GO:0031490 chromatin DNA binding; GO:0005085 guanyl-nucleotide exchange factor activity; GO:0044877 macromolecular complex binding; GO:0005087 Ran guanyl-nucleotide exchange factor activity; GO:0005515 protein binding; GO:0003682 chromatin binding; GO:0098772 molecular function regulator; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0031491 nucleosome binding; GO:0005088 Ras guanyl-nucleotide exchange factor activity; GO:0031492 nucleosomal DNA binding; ","K11493",null,null,"IPR009091; ","Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II; \r"]
["P18827","Syndecan-1 OS=Homo sapiens OX=9606 GN=SDC1","SDC1",32.461,7.0343,10.3,2,2,2,0.915,0.831,0.783,1.124,1.153,1.183,1.368,0.00272,"extracellular\r","GO:0060627 regulation of vesicle-mediated transport; GO:0044700 single organism signaling; GO:0022414 reproductive process; GO:0007166 cell surface receptor signaling pathway; GO:0008584 male gonad development; GO:0046683 response to organophosphorus; GO:0045445 myoblast differentiation; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0030203 glycosaminoglycan metabolic process; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0032879 regulation of localization; GO:0044702 single organism reproductive process; GO:0048545 response to steroid hormone; GO:0009719 response to endogenous stimulus; GO:0043170 macromolecule metabolic process; GO:0016055 Wnt signaling pathway; GO:1903543 positive regulation of exosomal secretion; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0003006 developmental process involved in reproduction; GO:0002064 epithelial cell development; GO:0045921 positive regulation of exocytosis; GO:0000302 response to reactive oxygen species; GO:0044763 single-organism cellular process; GO:0060008 Sertoli cell differentiation; GO:0048870 cell motility; GO:0032501 multicellular organismal process; GO:0006027 glycosaminoglycan catabolic process; GO:1901575 organic substance catabolic process; GO:0010243 response to organonitrogen compound; GO:0048513 animal organ development; GO:0050900 leukocyte migration; GO:0055002 striated muscle cell development; GO:0051591 response to cAMP; GO:0007267 cell-cell signaling; GO:0044710 single-organism metabolic process; GO:1901698 response to nitrogen compound; GO:0009887 animal organ morphogenesis; GO:0016101 diterpenoid metabolic process; GO:0030855 epithelial cell differentiation; GO:0051047 positive regulation of secretion; GO:0000003 reproduction; GO:0055001 muscle cell development; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0008406 gonad development; GO:1901700 response to oxygen-containing compound; GO:0017157 regulation of exocytosis; GO:1903541 regulation of exosomal secretion; GO:0048627 myoblast development; GO:0009653 anatomical structure morphogenesis; GO:0014074 response to purine-containing compound; GO:0007548 sex differentiation; GO:1901135 carbohydrate derivative metabolic process; GO:0061061 muscle structure development; GO:0007275 multicellular organism development; GO:0061458 reproductive system development; GO:0001822 kidney development; GO:0006720 isoprenoid metabolic process; GO:0006023 aminoglycan biosynthetic process; GO:0006950 response to stress; GO:0048731 system development; GO:1901136 carbohydrate derivative catabolic process; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0042542 response to hydrogen peroxide; GO:0006928 movement of cell or subcellular component; GO:0072073 kidney epithelium development; GO:0046546 development of primary male sexual characteristics; GO:0051179 localization; GO:0001657 ureteric bud development; GO:1901564 organonitrogen compound metabolic process; GO:0051674 localization of cell; GO:0006024 glycosaminoglycan biosynthetic process; GO:0048869 cellular developmental process; GO:0006026 aminoglycan catabolic process; GO:0044699 single-organism process; GO:0051046 regulation of secretion; GO:0009058 biosynthetic process; GO:1902115 regulation of organelle assembly; GO:0001823 mesonephros development; GO:0051130 positive regulation of cellular component organization; GO:0009611 response to wounding; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0006979 response to oxidative stress; GO:0060070 canonical Wnt signaling pathway; GO:0010035 response to inorganic substance; GO:0006629 lipid metabolic process; GO:0032502 developmental process; GO:0035295 tube development; GO:0060429 epithelium development; GO:0009888 tissue development; GO:0009636 response to toxic substance; GO:0048608 reproductive structure development; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:1903530 regulation of secretion by cell; GO:0010038 response to metal ion; GO:0051384 response to glucocorticoid; GO:0198738 cell-cell signaling by wnt; GO:0051050 positive regulation of transport; GO:0042476 odontogenesis; GO:0001655 urogenital system development; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0010638 positive regulation of organelle organization; GO:1903532 positive regulation of secretion by cell; GO:1902117 positive regulation of organelle assembly; GO:0006954 inflammatory response; GO:0006952 defense response; GO:0040011 locomotion; GO:0072163 mesonephric epithelium development; GO:0048856 anatomical structure development; GO:0016477 cell migration; GO:0046661 male sex differentiation; GO:0072001 renal system development; GO:0044087 regulation of cellular component biogenesis; GO:0050896 response to stimulus; GO:1901566 organonitrogen compound biosynthetic process; GO:0048468 cell development; GO:0071704 organic substance metabolic process; GO:0033993 response to lipid; GO:0030154 cell differentiation; GO:0031960 response to corticosteroid; GO:0001523 retinoid metabolic process; GO:0051592 response to calcium ion; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006022 aminoglycan metabolic process; GO:0045137 development of primary sexual characteristics; GO:1903553 positive regulation of extracellular exosome assembly; GO:0051146 striated muscle cell differentiation; GO:1903551 regulation of extracellular exosome assembly; GO:0072164 mesonephric tubule development; GO:0051049 regulation of transport; GO:0033043 regulation of organelle organization; GO:0006807 nitrogen compound metabolic process; GO:0048518 positive regulation of biological process; GO:1901565 organonitrogen compound catabolic process; GO:0042060 wound healing; GO:0060009 Sertoli cell development; GO:0044767 single-organism developmental process; GO:0009057 macromolecule catabolic process; GO:0042692 muscle cell differentiation; GO:0006721 terpenoid metabolic process; GO:0051128 regulation of cellular component organization; GO:0009725 response to hormone; GO:0009056 catabolic process; GO:0044089 positive regulation of cellular component biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0009897 external side of plasma membrane; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0098552 side of membrane; GO:0043229 intracellular organelle; GO:0031226 intrinsic component of plasma membrane; GO:0044446 intracellular organelle part; GO:0005796 Golgi lumen; GO:0012505 endomembrane system; GO:0043202 lysosomal lumen; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044459 plasma membrane part; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0009986 cell surface; GO:0043234 protein complex; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0097367 carbohydrate derivative binding; GO:0008022 protein C-terminus binding; GO:0005515 protein binding; GO:0001948 glycoprotein binding; GO:0005488 binding; ","K06257","SDC1; syndecan 1","hsa05144 Malaria - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human); hsa04512 ECM-receptor interaction - Homo sapiens (human); hsa04514 Cell adhesion molecules (CAMs) - Homo sapiens (human); ","IPR027789; IPR003585; ","Syndecan/Neurexin domain; Neurexin/syndecan/glycophorin C; \r"]
["P18858","DNA ligase 1 OS=Homo sapiens OX=9606 GN=LIG1","LIG1",101.73,9.6401,3.5,3,3,3,0.917,0.951,0.873,1.097,1.071,1.09,1.189,0.00256,"nucleus\r","GO:0033554 cellular response to stress; GO:0006260 DNA replication; GO:0006266 DNA ligation; GO:0006283 transcription-coupled nucleotide-excision repair; GO:0006725 cellular aromatic compound metabolic process; GO:0006259 DNA metabolic process; GO:0006289 nucleotide-excision repair; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0050896 response to stimulus; GO:1903047 mitotic cell cycle process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0009653 anatomical structure morphogenesis; GO:0008152 metabolic process; GO:1903461 Okazaki fragment processing involved in mitotic DNA replication; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0033260 nuclear DNA replication; GO:0071897 DNA biosynthetic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0006261 DNA-dependent DNA replication; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006310 DNA recombination; GO:0044786 cell cycle DNA replication; GO:0032502 developmental process; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0006284 base-excision repair; GO:0006950 response to stress; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0051103 DNA ligation involved in DNA repair; GO:0044238 primary metabolic process; GO:0022616 DNA strand elongation; GO:1901576 organic substance biosynthetic process; GO:0006974 cellular response to DNA damage stimulus; GO:0044249 cellular biosynthetic process; GO:0016070 RNA metabolic process; GO:0033567 DNA replication, Okazaki fragment processing; GO:0006281 DNA repair; GO:0006298 mismatch repair; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0090304 nucleic acid metabolic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0006271 DNA strand elongation involved in DNA replication; GO:0044260 cellular macromolecule metabolic process; GO:0006273 lagging strand elongation; GO:0051301 cell division; GO:0022402 cell cycle process; GO:0006297 nucleotide-excision repair, DNA gap filling; GO:1902969 mitotic DNA replication; GO:0048856 anatomical structure development; GO:1901362 organic cyclic compound biosynthetic process; GO:0007049 cell cycle; ","GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0003677 DNA binding; GO:0005524 ATP binding; GO:0003910 DNA ligase (ATP) activity; GO:1901265 nucleoside phosphate binding; GO:0016874 ligase activity; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016886 ligase activity, forming phosphoric ester bonds; GO:0003909 DNA ligase activity; GO:0000166 nucleotide binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0032550 purine ribonucleoside binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K10747","LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]","hsa03430 Mismatch repair - Homo sapiens (human); hsa03420 Nucleotide excision repair - Homo sapiens (human); hsa03410 Base excision repair - Homo sapiens (human); hsa03030 DNA replication - Homo sapiens (human); ","IPR012340; IPR012308; IPR012310; IPR012309; ","\"Nucleic acid-binding, OB-fold; DNA ligase, ATP-dependent, N-terminal; DNA ligase, ATP-dependent, central; DNA ligase, ATP-dependent, C-terminal; \"\r"]
["P18859","ATP synthase-coupling factor 6, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5J","ATP5J",12.587,80.76,51.9,6,11,6,1.032,1.083,0.994,0.949,0.955,1.015,0.939,0.128,"mitochondria\r","GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0007420 brain development; GO:0006839 mitochondrial transport; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0009163 nucleoside biosynthetic process; GO:0046129 purine ribonucleoside biosynthetic process; GO:0009156 ribonucleoside monophosphate biosynthetic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0048857 neural nucleus development; GO:0021762 substantia nigra development; GO:0046390 ribose phosphate biosynthetic process; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:1901137 carbohydrate derivative biosynthetic process; GO:0006753 nucleoside phosphate metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0060322 head development; GO:0009145 purine nucleoside triphosphate biosynthetic process; GO:0044765 single-organism transport; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0030901 midbrain development; GO:0018130 heterocycle biosynthetic process; GO:0009206 purine ribonucleoside triphosphate biosynthetic process; GO:0098655 cation transmembrane transport; GO:0044281 small molecule metabolic process; GO:0006754 ATP biosynthetic process; GO:0044763 single-organism cellular process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0015985 energy coupled proton transport, down electrochemical gradient; GO:0032501 multicellular organismal process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0009168 purine ribonucleoside monophosphate biosynthetic process; GO:1902582 single-organism intracellular transport; GO:0042451 purine nucleoside biosynthetic process; GO:0090407 organophosphate biosynthetic process; GO:0006810 transport; GO:0048513 animal organ development; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0007417 central nervous system development; GO:0072522 purine-containing compound biosynthetic process; GO:0044710 single-organism metabolic process; GO:0015986 ATP synthesis coupled proton transport; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0006164 purine nucleotide biosynthetic process; GO:0048856 anatomical structure development; GO:1901362 organic cyclic compound biosynthetic process; GO:0098662 inorganic cation transmembrane transport; GO:0009201 ribonucleoside triphosphate biosynthetic process; GO:0044707 single-multicellular organism process; GO:0046907 intracellular transport; GO:0009165 nucleotide biosynthetic process; GO:0034220 ion transmembrane transport; GO:0042776 mitochondrial ATP synthesis coupled proton transport; GO:0006725 cellular aromatic compound metabolic process; GO:0009259 ribonucleotide metabolic process; GO:0009142 nucleoside triphosphate biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006812 cation transport; GO:0006139 nucleobase-containing compound metabolic process; GO:1990542 mitochondrial transmembrane transport; GO:1902600 hydrogen ion transmembrane transport; GO:1901135 carbohydrate derivative metabolic process; GO:1902580 single-organism cellular localization; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009119 ribonucleoside metabolic process; GO:0009987 cellular process; GO:0046034 ATP metabolic process; GO:0009124 nucleoside monophosphate biosynthetic process; GO:0044711 single-organism biosynthetic process; GO:0098660 inorganic ion transmembrane transport; GO:0048731 system development; GO:0009127 purine nucleoside monophosphate biosynthetic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0042455 ribonucleoside biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0006818 hydrogen transport; GO:0015992 proton transport; GO:0006163 purine nucleotide metabolic process; GO:0051641 cellular localization; GO:0055085 transmembrane transport; GO:0046128 purine ribonucleoside metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0009152 purine ribonucleotide biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0044767 single-organism developmental process; GO:1901659 glycosyl compound biosynthetic process; GO:0006811 ion transport; GO:0009260 ribonucleotide biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0051179 localization; GO:0015672 monovalent inorganic cation transport; GO:1901564 organonitrogen compound metabolic process; GO:0009123 nucleoside monophosphate metabolic process; ","GO:0016020 membrane; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044455 mitochondrial membrane part; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain; GO:0005743 mitochondrial inner membrane; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o); GO:0045259 proton-transporting ATP synthase complex; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005753 mitochondrial proton-transporting ATP synthase complex; GO:0016469 proton-transporting two-sector ATPase complex; GO:0031975 envelope; GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o); GO:0043234 protein complex; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0015075 ion transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0015077 monovalent inorganic cation transmembrane transporter activity; GO:0022890 inorganic cation transmembrane transporter activity; GO:0015078 hydrogen ion transmembrane transporter activity; GO:0008324 cation transmembrane transporter activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; ","K02131","ATPeF0F6; F-type H+-transporting ATPase subunit 6","hsa05010 Alzheimer's disease - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); "]
["P18887","DNA repair protein XRCC1 OS=Homo sapiens OX=9606 GN=XRCC1","XRCC1",69.476,6.9608,6.2,3,3,3,0.685,0.823,0.897,1.184,1.186,1.205,1.486,0.037,"nucleus\r","GO:0065008 regulation of biological quality; GO:0006266 DNA ligation; GO:0021766 hippocampus development; GO:0007420 brain development; GO:0051129 negative regulation of cellular component organization; GO:0006289 nucleotide-excision repair; GO:1904353 regulation of telomere capping; GO:1904506 negative regulation of telomere maintenance in response to DNA damage; GO:0044699 single-organism process; GO:0000012 single strand break repair; GO:0021761 limbic system development; GO:0032204 regulation of telomere maintenance; GO:0044237 cellular metabolic process; GO:0021537 telencephalon development; GO:1905764 regulation of protection from non-homologous end joining at telomere; GO:0008152 metabolic process; GO:0060322 head development; GO:0043170 macromolecule metabolic process; GO:0006310 DNA recombination; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0006288 base-excision repair, DNA ligation; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0032501 multicellular organismal process; GO:0000722 telomere maintenance via recombination; GO:0010639 negative regulation of organelle organization; GO:2001021 negative regulation of response to DNA damage stimulus; GO:0048513 animal organ development; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0051052 regulation of DNA metabolic process; GO:0080135 regulation of cellular response to stress; GO:0090304 nucleic acid metabolic process; GO:0051053 negative regulation of DNA metabolic process; GO:0007417 central nervous system development; GO:0048583 regulation of response to stimulus; GO:1904505 regulation of telomere maintenance in response to DNA damage; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0032200 telomere organization; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0006297 nucleotide-excision repair, DNA gap filling; GO:0006312 mitotic recombination; GO:0048856 anatomical structure development; GO:0006303 double-strand break repair via nonhomologous end joining; GO:0021543 pallium development; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0033554 cellular response to stress; GO:0044707 single-multicellular organism process; GO:0006725 cellular aromatic compound metabolic process; GO:0006283 transcription-coupled nucleotide-excision repair; GO:2001020 regulation of response to DNA damage stimulus; GO:0009628 response to abiotic stimulus; GO:0006259 DNA metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0006302 double-strand break repair; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:1905765 negative regulation of protection from non-homologous end joining at telomere; GO:0050896 response to stimulus; GO:0032844 regulation of homeostatic process; GO:0060249 anatomical structure homeostasis; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0042493 response to drug; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0001666 response to hypoxia; GO:0070482 response to oxygen levels; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0030900 forebrain development; GO:0007275 multicellular organism development; GO:0000724 double-strand break repair via homologous recombination; GO:0009987 cellular process; GO:0006284 base-excision repair; GO:0006950 response to stress; GO:1904354 negative regulation of telomere capping; GO:0000726 non-recombinational repair; GO:0048731 system development; GO:0006807 nitrogen compound metabolic process; GO:0033043 regulation of organelle organization; GO:0051103 DNA ligation involved in DNA repair; GO:0010033 response to organic substance; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0048585 negative regulation of response to stimulus; GO:0032845 negative regulation of homeostatic process; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0033044 regulation of chromosome organization; GO:0006974 cellular response to DNA damage stimulus; GO:0032205 negative regulation of telomere maintenance; GO:0000725 recombinational repair; GO:0006281 DNA repair; GO:2001251 negative regulation of chromosome organization; GO:0061819 telomeric DNA-containing double minutes formation; GO:0051276 chromosome organization; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0036293 response to decreased oxygen levels; GO:0051128 regulation of cellular component organization; GO:0000723 telomere maintenance; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0000784 nuclear chromosome, telomeric region; GO:0000781 chromosome, telomeric region; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044454 nuclear chromosome part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:1990391 DNA repair complex; GO:0043226 organelle; GO:0098687 chromosomal region; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0070522 ERCC4-ERCC1 complex; GO:0000228 nuclear chromosome; GO:0043234 protein complex; GO:0000109 nucleotide-excision repair complex; GO:0044428 nuclear part; ","GO:0003677 DNA binding; GO:0004536 deoxyribonuclease activity; GO:0016874 ligase activity; GO:0004520 endodeoxyribonuclease activity; GO:0016886 ligase activity, forming phosphoric ester bonds; GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0003909 DNA ligase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0000014 single-stranded DNA endodeoxyribonuclease activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0004518 nuclease activity; GO:0016788 hydrolase activity, acting on ester bonds; GO:0003684 damaged DNA binding; GO:0019899 enzyme binding; GO:0004519 endonuclease activity; ","K10803","XRCC1; DNA-repair protein XRCC1","hsa03410 Base excision repair - Homo sapiens (human); ","IPR002706; IPR008979; IPR001357; ","\"DNA-repair protein Xrcc1, N-terminal; Galactose-binding domain-like; BRCT domain; \"\r"]
["P19075","Tetraspanin-8 OS=Homo sapiens OX=9606 GN=TSPAN8","TSPAN8",26.044,4.8158,4.2,1,1,1,1.29,1.319,1.155,0.83,0.757,0.698,0.607,0.00152,"plasma membrane\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0007166 cell surface receptor signaling pathway; GO:0030193 regulation of blood coagulation; GO:0044699 single-organism process; GO:0051241 negative regulation of multicellular organismal process; GO:0048519 negative regulation of biological process; GO:0080134 regulation of response to stress; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:1900047 negative regulation of hemostasis; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0032102 negative regulation of response to external stimulus; GO:1900046 regulation of hemostasis; GO:0009987 cellular process; GO:0051716 cellular response to stimulus; GO:0050878 regulation of body fluid levels; GO:0032101 regulation of response to external stimulus; GO:0048585 negative regulation of response to stimulus; GO:0023052 signaling; GO:0061045 negative regulation of wound healing; GO:1903035 negative regulation of response to wounding; GO:0050818 regulation of coagulation; GO:0030195 negative regulation of blood coagulation; GO:0050789 regulation of biological process; GO:0061041 regulation of wound healing; GO:0048583 regulation of response to stimulus; GO:1903034 regulation of response to wounding; GO:0050819 negative regulation of coagulation; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0031226 intrinsic component of plasma membrane; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0044459 plasma membrane part; GO:0044464 cell part; GO:0044425 membrane part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0050839 cell adhesion molecule binding; GO:0005102 receptor binding; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0005515 protein binding; GO:0005178 integrin binding; GO:0032403 protein complex binding; ","K17349",null,null,"IPR008952; ","\"Tetraspanin, EC2 domain; \"\r"]
["P19105","Myosin regulatory light chain 12A OS=Homo sapiens OX=9606 GN=MYL12A","MYL12A",19.794,123.38,66.7,11,23,4,0.985,0.977,0.968,1.029,0.987,1.067,1.052,0.0942,"mitochondria\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0044707 single-multicellular organism process; GO:0065008 regulation of biological quality; GO:0007596 blood coagulation; GO:0003012 muscle system process; GO:0007166 cell surface receptor signaling pathway; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0034109 homotypic cell-cell adhesion; GO:0007599 hemostasis; GO:0009611 response to wounding; GO:0022610 biological adhesion; GO:0016337 single organismal cell-cell adhesion; GO:0007165 signal transduction; GO:0006936 muscle contraction; GO:0048013 ephrin receptor signaling pathway; GO:0007154 cell communication; GO:0007155 cell adhesion; GO:0009987 cellular process; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0051716 cellular response to stimulus; GO:0003008 system process; GO:0050878 regulation of body fluid levels; GO:0006950 response to stress; GO:0030168 platelet activation; GO:0044763 single-organism cellular process; GO:0098609 cell-cell adhesion; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0050789 regulation of biological process; GO:0042060 wound healing; GO:0098602 single organism cell adhesion; GO:0001775 cell activation; GO:0050817 coagulation; GO:0070527 platelet aggregation; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0015629 actin cytoskeleton; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0016459 myosin complex; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0005509 calcium ion binding; GO:0005488 binding; GO:0043167 ion binding; ","K12757","MYL12; myosin regulatory light chain 12","hsa04611 Platelet activation - Homo sapiens (human); hsa04670 Leukocyte transendothelial migration - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa04530 Tight junction - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); ","IPR015070; IPR011992; IPR002048; ","\"DJBP, EF-hand domain; EF-hand domain pair; EF-hand domain; \"\r"]
["P19174","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 OS=Homo sapiens OX=9606 GN=PLCG1","PLCG1",148.53,10.769,2.2,2,2,2,0.94,1.096,1.008,1.07,0.911,0.989,0.976,0.719,"nucleus\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0030335 positive regulation of cell migration; GO:0032270 positive regulation of cellular protein metabolic process; GO:0007166 cell surface receptor signaling pathway; GO:0006066 alcohol metabolic process; GO:0043009 chordate embryonic development; GO:0032989 cellular component morphogenesis; GO:0044255 cellular lipid metabolic process; GO:1904427 positive regulation of calcium ion transmembrane transport; GO:0044237 cellular metabolic process; GO:0010594 regulation of endothelial cell migration; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:1904018 positive regulation of vasculature development; GO:0009719 response to endogenous stimulus; GO:0038127 ERBB signaling pathway; GO:0070848 response to growth factor; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0051347 positive regulation of transferase activity; GO:0009790 embryo development; GO:0044419 interspecies interaction between organisms; GO:0044765 single-organism transport; GO:0007399 nervous system development; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0051174 regulation of phosphorus metabolic process; GO:0010632 regulation of epithelial cell migration; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0044281 small molecule metabolic process; GO:0043269 regulation of ion transport; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0019932 second-messenger-mediated signaling; GO:0048812 neuron projection morphogenesis; GO:0051272 positive regulation of cellular component movement; GO:0048870 cell motility; GO:0031323 regulation of cellular metabolic process; GO:0006935 chemotaxis; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0034762 regulation of transmembrane transport; GO:0000902 cell morphogenesis; GO:1901575 organic substance catabolic process; GO:0050900 leukocyte migration; GO:0001701 in utero embryonic development; GO:0071364 cellular response to epidermal growth factor stimulus; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0010604 positive regulation of macromolecule metabolic process; GO:0002682 regulation of immune system process; GO:0042330 taxis; GO:0045765 regulation of angiogenesis; GO:0051094 positive regulation of developmental process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0034764 positive regulation of transmembrane transport; GO:1901615 organic hydroxy compound metabolic process; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0031399 regulation of protein modification process; GO:2000147 positive regulation of cell motility; GO:0007173 epidermal growth factor receptor signaling pathway; GO:0032844 regulation of homeostatic process; GO:0051239 regulation of multicellular organismal process; GO:0060341 regulation of cellular localization; GO:0009653 anatomical structure morphogenesis; GO:1902578 single-organism localization; GO:0019722 calcium-mediated signaling; GO:0032147 activation of protein kinase activity; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:2000145 regulation of cell motility; GO:0007409 axonogenesis; GO:0051338 regulation of transferase activity; GO:0010959 regulation of metal ion transport; GO:0044248 cellular catabolic process; GO:0007275 multicellular organism development; GO:0038093 Fc receptor signaling pathway; GO:0050778 positive regulation of immune response; GO:0009966 regulation of signal transduction; GO:1904062 regulation of cation transmembrane transport; GO:0051928 positive regulation of calcium ion transport; GO:0002253 activation of immune response; GO:0016042 lipid catabolic process; GO:0051282 regulation of sequestering of calcium ion; GO:1902531 regulation of intracellular signal transduction; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0051924 regulation of calcium ion transport; GO:0002376 immune system process; GO:0030334 regulation of cell migration; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0019751 polyol metabolic process; GO:0043270 positive regulation of ion transport; GO:0030182 neuron differentiation; GO:0043535 regulation of blood vessel endothelial cell migration; GO:0051247 positive regulation of protein metabolic process; GO:1904064 positive regulation of cation transmembrane transport; GO:0006793 phosphorus metabolic process; GO:0097485 neuron projection guidance; GO:0031325 positive regulation of cellular metabolic process; GO:0044242 cellular lipid catabolic process; GO:0019637 organophosphate metabolic process; GO:0006928 movement of cell or subcellular component; GO:0043647 inositol phosphate metabolic process; GO:0006644 phospholipid metabolic process; GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0051674 localization of cell; GO:0040017 positive regulation of locomotion; GO:0038094 Fc-gamma receptor signaling pathway; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0071363 cellular response to growth factor stimulus; GO:0044764 multi-organism cellular process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0006909 phagocytosis; GO:0000186 activation of MAPKK activity; GO:0009395 phospholipid catabolic process; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0032990 cell part morphogenesis; GO:0009893 positive regulation of metabolic process; GO:0032846 positive regulation of homeostatic process; GO:0048858 cell projection morphogenesis; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0033674 positive regulation of kinase activity; GO:0070887 cellular response to chemical stimulus; GO:0043536 positive regulation of blood vessel endothelial cell migration; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0050851 antigen receptor-mediated signaling pathway; GO:0006629 lipid metabolic process; GO:0032502 developmental process; GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis; GO:0045937 positive regulation of phosphate metabolic process; GO:0051279 regulation of release of sequestered calcium ion into cytosol; GO:0090280 positive regulation of calcium ion import; GO:0048522 positive regulation of cellular process; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0051050 positive regulation of transport; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0034767 positive regulation of ion transmembrane transport; GO:0030030 cell projection organization; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0002431 Fc receptor mediated stimulatory signaling pathway; GO:0040011 locomotion; GO:0019220 regulation of phosphate metabolic process; GO:0048856 anatomical structure development; GO:0043549 regulation of kinase activity; GO:2000026 regulation of multicellular organismal development; GO:0045859 regulation of protein kinase activity; GO:0016043 cellular component organization; GO:0016477 cell migration; GO:2000021 regulation of ion homeostasis; GO:0002252 immune effector process; GO:0010595 positive regulation of endothelial cell migration; GO:0046434 organophosphate catabolic process; GO:0043405 regulation of MAP kinase activity; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0050896 response to stimulus; GO:0045766 positive regulation of angiogenesis; GO:0007411 axon guidance; GO:0048468 cell development; GO:0000904 cell morphogenesis involved in differentiation; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0043408 regulation of MAPK cascade; GO:0016032 viral process; GO:0023056 positive regulation of signaling; GO:1903169 regulation of calcium ion transmembrane transport; GO:0002757 immune response-activating signal transduction; GO:0010647 positive regulation of cell communication; GO:0010524 positive regulation of calcium ion transport into cytosol; GO:0009987 cellular process; GO:0070849 response to epidermal growth factor; GO:0035556 intracellular signal transduction; GO:0051049 regulation of transport; GO:0044712 single-organism catabolic process; GO:0009792 embryo development ending in birth or egg hatching; GO:0090279 regulation of calcium ion import; GO:1901342 regulation of vasculature development; GO:0001932 regulation of protein phosphorylation; GO:0031401 positive regulation of protein modification process; GO:0010634 positive regulation of epithelial cell migration; GO:0006897 endocytosis; GO:0031175 neuron projection development; GO:0001934 positive regulation of protein phosphorylation; GO:0045860 positive regulation of protein kinase activity; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0061564 axon development; GO:0050852 T cell receptor signaling pathway; GO:0034765 regulation of ion transmembrane transport; GO:0051281 positive regulation of release of sequestered calcium ion into cytosol; GO:0071495 cellular response to endogenous stimulus; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0002684 positive regulation of immune system process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0038095 Fc-epsilon receptor signaling pathway; GO:0010522 regulation of calcium ion transport into cytosol; GO:0009967 positive regulation of signal transduction; GO:0040012 regulation of locomotion; GO:0043410 positive regulation of MAPK cascade; GO:0009056 catabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0031252 cell leading edge; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005911 cell-cell junction; GO:0008180 COP9 signalosome; GO:0005623 cell; GO:0044422 organelle part; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:0030027 lamellipodium; GO:0001726 ruffle; GO:0043227 membrane-bounded organelle; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005167 neurotrophin TRK receptor binding; GO:1990782 protein tyrosine kinase binding; GO:0005102 receptor binding; GO:0004629 phospholipase C activity; GO:0005126 cytokine receptor binding; GO:0043167 ion binding; GO:0019901 protein kinase binding; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0016298 lipase activity; GO:0019900 kinase binding; GO:0004871 signal transducer activity; GO:0005165 neurotrophin receptor binding; GO:0035254 glutamate receptor binding; GO:0004435 phosphatidylinositol phospholipase C activity; GO:0005057 signal transducer activity, downstream of receptor; GO:0030971 receptor tyrosine kinase binding; GO:0003824 catalytic activity; GO:0042578 phosphoric ester hydrolase activity; GO:0005488 binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0004620 phospholipase activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005168 neurotrophin TRKA receptor binding; GO:0008081 phosphoric diester hydrolase activity; GO:0005509 calcium ion binding; GO:0019899 enzyme binding; ","K01116","PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]","hsa04072 Phospholipase D signaling pathway - Homo sapiens (human); hsa04015 Rap1 signaling pathway - Homo sapiens (human); hsa04650 Natural killer cell mediated cytotoxicity - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa04014 Ras signaling pathway - Homo sapiens (human); hsa05110 Vibrio cholerae infection - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa05206 MicroRNAs in cancer - Homo sapiens (human); hsa00562 Inositol phosphate metabolism - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa04070 Phosphatidylinositol signaling system - Homo sapiens (human); hsa04933 AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human); hsa04659 Th17 cell differentiation - Homo sapiens (human); hsa01521 EGFR tyrosine kinase inhibitor resistance - Homo sapiens (human); hsa04064 NF-kappa B signaling pathway - Homo sapiens (human); hsa05120 Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human); hsa05231 Choline metabolism in cancer - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); hsa04722 Neurotrophin signaling pathway - Homo sapiens (human); hsa04370 VEGF signaling pathway - Homo sapiens (human); hsa04020 Calcium signaling pathway - Homo sapiens (human); hsa05167 Kaposi's sarcoma-associated herpesvirus infection - Homo sapiens (human); hsa05225 Hepatocellular carcinoma - Homo sapiens (human); hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human); hsa04670 Leukocyte transendothelial migration - Homo sapiens (human); hsa04660 T cell receptor signaling pathway - Homo sapiens (human); hsa04750 Inflammatory mediator regulation of TRP channels - Homo sapiens (human); hsa04658 Th1 and Th2 cell differentiation - Homo sapiens (human); hsa04666 Fc gamma R-mediated phagocytosis - Homo sapiens (human); hsa05223 Non-small cell lung cancer - Homo sapiens (human); hsa04664 Fc epsilon RI signaling pathway - Homo sapiens (human); hsa04066 HIF-1 signaling pathway - Homo sapiens (human); hsa05214 Glioma - Homo sapiens (human); hsa04012 ErbB signaling pathway - Homo sapiens (human); hsa04360 Axon guidance - Homo sapiens (human); ","IPR000909; IPR002048; IPR011992; IPR001849; IPR001711; IPR000980; IPR001452; IPR017946; IPR011993; IPR000008; ","\"Phosphatidylinositol-specific phospholipase C, X domain; EF-hand domain; EF-hand domain pair; Pleckstrin homology domain; Phospholipase C, phosphatidylinositol-specific, Y domain; SH2 domain; SH3 domain; PLC-like phosphodiesterase, TIM beta/alpha-barrel domain; PH domain-like; C2 domain; \"\r"]
["P19338","Nucleolin OS=Homo sapiens OX=9606 GN=NCL","NCL",76.613,229.24,31.4,29,62,29,0.88,0.86,0.907,1.126,1.119,1.105,1.266,0.000138,"nucleus\r","GO:0001568 blood vessel development; GO:0009891 positive regulation of biosynthetic process; GO:0044699 single-organism process; GO:0071363 cellular response to growth factor stimulus; GO:1901836 regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter; GO:2001141 regulation of RNA biosynthetic process; GO:0001525 angiogenesis; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0009719 response to endogenous stimulus; GO:0070848 response to growth factor; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0048514 blood vessel morphogenesis; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter; GO:0045893 positive regulation of transcription, DNA-templated; GO:0001944 vasculature development; GO:0048522 positive regulation of cellular process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0071364 cellular response to epidermal growth factor stimulus; GO:0006356 regulation of transcription from RNA polymerase I promoter; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0048856 anatomical structure development; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0072359 circulatory system development; GO:0044707 single-multicellular organism process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0071310 cellular response to organic substance; GO:0050896 response to stimulus; GO:0009653 anatomical structure morphogenesis; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0051254 positive regulation of RNA metabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0070849 response to epidermal growth factor; GO:0048731 system development; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0072358 cardiovascular system development; GO:0010033 response to organic substance; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0044767 single-organism developmental process; GO:0071495 cellular response to endogenous stimulus; GO:0031325 positive regulation of cellular metabolic process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0045943 positive regulation of transcription from RNA polymerase I promoter; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005938 cell cortex; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0099568 cytoplasmic region; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0035770 ribonucleoprotein granule; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003677 DNA binding; GO:0003723 RNA binding; GO:0042802 identical protein binding; GO:1901265 nucleoside phosphate binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0042162 telomeric DNA binding; GO:0008022 protein C-terminus binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0043565 sequence-specific DNA binding; GO:0036094 small molecule binding; ","K11294","NCL; nucleolin","hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human); ","IPR034230; IPR034235; IPR000504; IPR012677; IPR003954; IPR034233; IPR034234; ","\"Nucleolin, RNA recognition motif 1; Nucleolin, RNA recognition motif 4; RNA recognition motif domain; Nucleotide-binding alpha-beta plait domain; RNA recognition motif domain, eukaryote; Nucleolin, RNA recognition motif 2; Nucleolin, RNA recognition motif 3; \"\r"]
["P19367","Hexokinase-1 OS=Homo sapiens OX=9606 GN=HK1","HK1",102.48,240.93,37,31,58,29,1.01,0.997,0.997,1.002,0.985,1.023,1.002,0.88,"cytoplasm\r","GO:0046365 monosaccharide catabolic process; GO:0006757 ATP generation from ADP; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0065008 regulation of biological quality; GO:0072594 establishment of protein localization to organelle; GO:0006165 nucleoside diphosphate phosphorylation; GO:0046031 ADP metabolic process; GO:0019362 pyridine nucleotide metabolic process; GO:0006096 glycolytic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0042593 glucose homeostasis; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009185 ribonucleoside diphosphate metabolic process; GO:0046939 nucleotide phosphorylation; GO:0009135 purine nucleoside diphosphate metabolic process; GO:0072524 pyridine-containing compound metabolic process; GO:0044237 cellular metabolic process; GO:0061615 glycolytic process through fructose-6-phosphate; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0006006 glucose metabolic process; GO:0072595 maintenance of protein localization in organelle; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0044262 cellular carbohydrate metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0001678 cellular glucose homeostasis; GO:0015758 glucose transport; GO:0032787 monocarboxylic acid metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0033365 protein localization to organelle; GO:0051651 maintenance of location in cell; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0044765 single-organism transport; GO:0051220 cytoplasmic sequestering of protein; GO:0009179 purine ribonucleoside diphosphate metabolic process; GO:0032507 maintenance of protein location in cell; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0019725 cellular homeostasis; GO:0061620 glycolytic process through glucose-6-phosphate; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0006732 coenzyme metabolic process; GO:0005975 carbohydrate metabolic process; GO:0061718 glucose catabolic process to pyruvate; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0016052 carbohydrate catabolic process; GO:0051186 cofactor metabolic process; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0008645 hexose transport; GO:0019674 NAD metabolic process; GO:0044710 single-organism metabolic process; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0006082 organic acid metabolic process; GO:0072655 establishment of protein localization to mitochondrion; GO:0043436 oxoacid metabolic process; GO:0016310 phosphorylation; GO:0072656 maintenance of protein location in mitochondrion; GO:0015749 monosaccharide transport; GO:0006725 cellular aromatic compound metabolic process; GO:0046496 nicotinamide nucleotide metabolic process; GO:0009259 ribonucleotide metabolic process; GO:0006734 NADH metabolic process; GO:0006735 NADH regeneration; GO:0055082 cellular chemical homeostasis; GO:0071704 organic substance metabolic process; GO:0061621 canonical glycolysis; GO:0042592 homeostatic process; GO:0051156 glucose 6-phosphate metabolic process; GO:0006090 pyruvate metabolic process; GO:0046483 heterocycle metabolic process; GO:1902578 single-organism localization; GO:0006139 nucleobase-containing compound metabolic process; GO:0046835 carbohydrate phosphorylation; GO:0005996 monosaccharide metabolic process; GO:0033500 carbohydrate homeostasis; GO:0008643 carbohydrate transport; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0051235 maintenance of location; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0034613 cellular protein localization; GO:0009119 ribonucleoside metabolic process; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0009132 nucleoside diphosphate metabolic process; GO:0046034 ATP metabolic process; GO:0044724 single-organism carbohydrate catabolic process; GO:0045185 maintenance of protein location; GO:0044712 single-organism catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0044282 small molecule catabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0070585 protein localization to mitochondrion; GO:0006163 purine nucleotide metabolic process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0046128 purine ribonucleoside metabolic process; GO:0006007 glucose catabolic process; GO:0070727 cellular macromolecule localization; GO:0006793 phosphorus metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0019637 organophosphate metabolic process; GO:0019320 hexose catabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0051179 localization; GO:0009056 catabolic process; GO:0019318 hexose metabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0019867 outer membrane; GO:0031090 organelle membrane; GO:0098857 membrane microdomain; GO:0005737 cytoplasm; GO:0036126 sperm flagellum; GO:0097729 9+2 motile cilium; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0044441 ciliary part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0098589 membrane region; GO:0031968 organelle outer membrane; GO:0045121 membrane raft; GO:0043227 membrane-bounded organelle; GO:0097228 sperm principal piece; GO:0005929 cilium; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0098588 bounding membrane of organelle; GO:0044429 mitochondrial part; GO:0005741 mitochondrial outer membrane; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0044463 cell projection part; GO:0031514 motile cilium; GO:0005829 cytosol; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031975 envelope; GO:0097223 sperm part; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0005515 protein binding; GO:0048029 monosaccharide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0016301 kinase activity; GO:0008865 fructokinase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0004340 glucokinase activity; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0004396 hexokinase activity; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0019158 mannokinase activity; GO:0005524 ATP binding; GO:0005536 glucose binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0032549 ribonucleoside binding; GO:0019200 carbohydrate kinase activity; GO:0097367 carbohydrate derivative binding; GO:0030246 carbohydrate binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0036094 small molecule binding; ","K00844","HK; hexokinase [EC:2.7.1.1]","hsa00051 Fructose and mannose metabolism - Homo sapiens (human); hsa04066 HIF-1 signaling pathway - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa04973 Carbohydrate digestion and absorption - Homo sapiens (human); hsa00500 Starch and sucrose metabolism - Homo sapiens (human); hsa04910 Insulin signaling pathway - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); hsa05230 Central carbon metabolism in cancer - Homo sapiens (human); hsa00524 Neomycin, kanamycin and gentamicin biosynthesis - Homo sapiens (human); hsa04930 Type II diabetes mellitus - Homo sapiens (human); hsa00052 Galactose metabolism - Homo sapiens (human); hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human); hsa00520 Amino sugar and nucleotide sugar metabolism - Homo sapiens (human); ","IPR022672; IPR022673; ","\"Hexokinase, N-terminal; Hexokinase, C-terminal; \"\r"]
["P19387","DNA-directed RNA polymerase II subunit RPB3 OS=Homo sapiens OX=9606 GN=POLR2C","POLR2C",31.441,4.5399,3.6,1,2,1,0.98,1.223,0.892,0.96,1.001,0.963,0.945,0.661,"cytoskeleton\r","GO:0044700 single organism signaling; GO:0007166 cell surface receptor signaling pathway; GO:0097659 nucleic acid-templated transcription; GO:0006289 nucleotide-excision repair; GO:0009891 positive regulation of biosynthetic process; GO:0006354 DNA-templated transcription, elongation; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0009719 response to endogenous stimulus; GO:0070848 response to growth factor; GO:0043170 macromolecule metabolic process; GO:0006396 RNA processing; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0050434 positive regulation of viral transcription; GO:0031047 gene silencing by RNA; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0044707 single-multicellular organism process; GO:0006283 transcription-coupled nucleotide-excision repair; GO:0035019 somatic stem cell population maintenance; GO:0006259 DNA metabolic process; GO:0048519 negative regulation of biological process; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0098781 ncRNA transcription; GO:0000375 RNA splicing, via transesterification reactions; GO:0071774 response to fibroblast growth factor; GO:0016073 snRNA metabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0008380 RNA splicing; GO:0051254 positive regulation of RNA metabolic process; GO:0006370 7-methylguanosine mRNA capping; GO:0006950 response to stress; GO:0043900 regulation of multi-organism process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006368 transcription elongation from RNA polymerase II promoter; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0006974 cellular response to DNA damage stimulus; GO:0046782 regulation of viral transcription; GO:0031325 positive regulation of cellular metabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0042795 snRNA transcription from RNA polymerase II promoter; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0071363 cellular response to growth factor stimulus; GO:0008543 fibroblast growth factor receptor signaling pathway; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0070887 cellular response to chemical stimulus; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0032502 developmental process; GO:1903902 positive regulation of viral life cycle; GO:0010468 regulation of gene expression; GO:0036260 RNA capping; GO:0043902 positive regulation of multi-organism process; GO:0031326 regulation of cellular biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:0009301 snRNA transcription; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0098727 maintenance of cell number; GO:0019222 regulation of metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0006352 DNA-templated transcription, initiation; GO:0009452 7-methylguanosine RNA capping; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0019827 stem cell population maintenance; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006367 transcription initiation from RNA polymerase II promoter; GO:0010629 negative regulation of gene expression; GO:0050792 regulation of viral process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0006281 DNA repair; GO:0016458 gene silencing; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0048524 positive regulation of viral process; GO:0044767 single-organism developmental process; GO:0071495 cellular response to endogenous stimulus; GO:0006366 transcription from RNA polymerase II promoter; GO:0044344 cellular response to fibroblast growth factor stimulus; GO:0010467 gene expression; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:1903900 regulation of viral life cycle; GO:0034660 ncRNA metabolic process; GO:0065007 biological regulation; ","GO:0005665 DNA-directed RNA polymerase II, core complex; GO:0061695 transferase complex, transferring phosphorus-containing groups; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0055029 nuclear DNA-directed RNA polymerase complex; GO:0000428 DNA-directed RNA polymerase complex; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0030880 RNA polymerase complex; GO:0031981 nuclear lumen; GO:1990234 transferase complex; GO:0005829 cytosol; GO:0016591 DNA-directed RNA polymerase II, holoenzyme; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003677 DNA binding; GO:0016779 nucleotidyltransferase activity; GO:0034062 5'-3' RNA polymerase activity; GO:0003824 catalytic activity; GO:0097747 RNA polymerase activity; GO:0005488 binding; GO:0046983 protein dimerization activity; GO:0003676 nucleic acid binding; GO:0003899 DNA-directed 5'-3' RNA polymerase activity; GO:0005515 protein binding; GO:0016740 transferase activity; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K03011","RPB3; DNA-directed RNA polymerase II subunit RPB3","hsa00230 Purine metabolism - Homo sapiens (human); hsa03020 RNA polymerase - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa00240 Pyrimidine metabolism - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR011262; IPR011263; IPR009025; ","\"DNA-directed RNA polymerase, insert domain; DNA-directed RNA polymerase, RpoA/D/Rpb3-type; DNA-directed RNA polymerase, RBP11-like dimerisation domain; \"\r"]
["P19388","DNA-directed RNA polymerases I, II, and III subunit RPABC1 OS=Homo sapiens OX=9606 GN=POLR2E","POLR2E",24.551,3.3127,8.1,2,2,2,0.97,0.925,0.971,1.053,1.042,1.042,1.095,0.00524,"cytoplasm\r","GO:0044700 single organism signaling; GO:0032481 positive regulation of type I interferon production; GO:0006360 transcription from RNA polymerase I promoter; GO:0007166 cell surface receptor signaling pathway; GO:0097659 nucleic acid-templated transcription; GO:0006289 nucleotide-excision repair; GO:0009891 positive regulation of biosynthetic process; GO:0006354 DNA-templated transcription, elongation; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0009719 response to endogenous stimulus; GO:0070848 response to growth factor; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0006396 RNA processing; GO:0051716 cellular response to stimulus; GO:0045815 positive regulation of gene expression, epigenetic; GO:0018130 heterocycle biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0050434 positive regulation of viral transcription; GO:0031047 gene silencing by RNA; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0033554 cellular response to stress; GO:0006283 transcription-coupled nucleotide-excision repair; GO:0035019 somatic stem cell population maintenance; GO:0006259 DNA metabolic process; GO:0001819 positive regulation of cytokine production; GO:0006362 transcription elongation from RNA polymerase I promoter; GO:0048519 negative regulation of biological process; GO:0051239 regulation of multicellular organismal process; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0098781 ncRNA transcription; GO:0000375 RNA splicing, via transesterification reactions; GO:0071774 response to fibroblast growth factor; GO:0016073 snRNA metabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0008380 RNA splicing; GO:0051254 positive regulation of RNA metabolic process; GO:0006370 7-methylguanosine mRNA capping; GO:0006950 response to stress; GO:0043900 regulation of multi-organism process; GO:0006368 transcription elongation from RNA polymerase II promoter; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0006974 cellular response to DNA damage stimulus; GO:0046782 regulation of viral transcription; GO:0031325 positive regulation of cellular metabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0006383 transcription from RNA polymerase III promoter; GO:0042795 snRNA transcription from RNA polymerase II promoter; GO:0006361 transcription initiation from RNA polymerase I promoter; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0071363 cellular response to growth factor stimulus; GO:0008543 fibroblast growth factor receptor signaling pathway; GO:0006363 termination of RNA polymerase I transcription; GO:0006353 DNA-templated transcription, termination; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0070887 cellular response to chemical stimulus; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:1903902 positive regulation of viral life cycle; GO:0036260 RNA capping; GO:0043902 positive regulation of multi-organism process; GO:0031326 regulation of cellular biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:0009301 snRNA transcription; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0098727 maintenance of cell number; GO:0019222 regulation of metabolic process; GO:0032479 regulation of type I interferon production; GO:0006725 cellular aromatic compound metabolic process; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0060255 regulation of macromolecule metabolic process; GO:0006352 DNA-templated transcription, initiation; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0009452 7-methylguanosine RNA capping; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0016032 viral process; GO:0034641 cellular nitrogen compound metabolic process; GO:0019827 stem cell population maintenance; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006367 transcription initiation from RNA polymerase II promoter; GO:0010629 negative regulation of gene expression; GO:0050792 regulation of viral process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0040029 regulation of gene expression, epigenetic; GO:0016458 gene silencing; GO:0006281 DNA repair; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0048524 positive regulation of viral process; GO:0044767 single-organism developmental process; GO:0071495 cellular response to endogenous stimulus; GO:0006366 transcription from RNA polymerase II promoter; GO:0044344 cellular response to fibroblast growth factor stimulus; GO:0001817 regulation of cytokine production; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0010467 gene expression; GO:1903900 regulation of viral life cycle; GO:0034660 ncRNA metabolic process; GO:0065007 biological regulation; ","GO:0005665 DNA-directed RNA polymerase II, core complex; GO:0061695 transferase complex, transferring phosphorus-containing groups; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0005736 DNA-directed RNA polymerase I complex; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0055029 nuclear DNA-directed RNA polymerase complex; GO:0000428 DNA-directed RNA polymerase complex; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0030880 RNA polymerase complex; GO:0031981 nuclear lumen; GO:0044452 nucleolar part; GO:0005730 nucleolus; GO:1990234 transferase complex; GO:0005829 cytosol; GO:0016591 DNA-directed RNA polymerase II, holoenzyme; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005666 DNA-directed RNA polymerase III complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003677 DNA binding; GO:0016779 nucleotidyltransferase activity; GO:0034062 5'-3' RNA polymerase activity; GO:0003824 catalytic activity; GO:0097747 RNA polymerase activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0003899 DNA-directed 5'-3' RNA polymerase activity; GO:0005515 protein binding; GO:0016740 transferase activity; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K03013","RPB5; DNA-directed RNA polymerases I, II, and III subunit RPABC1","hsa04623 Cytosolic DNA-sensing pathway - Homo sapiens (human); hsa00230 Purine metabolism - Homo sapiens (human); hsa03020 RNA polymerase - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa00240 Pyrimidine metabolism - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR005571; IPR000783; ","\"RNA polymerase, Rpb5, N-terminal; RNA polymerase, subunit H/Rpb5 C-terminal; \"\r"]
["P19404","NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV2","NDUFV2",27.391,33.961,28.9,7,13,7,1.029,0.998,1.082,0.945,1.04,1.012,0.964,0.374,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0008152 metabolic process; GO:0007507 heart development; GO:0006091 generation of precursor metabolites and energy; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0006753 nucleoside phosphate metabolic process; GO:0007005 mitochondrion organization; GO:0019693 ribose phosphate metabolic process; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0071822 protein complex subunit organization; GO:0009888 tissue development; GO:0010257 NADH dehydrogenase complex assembly; GO:0060537 muscle tissue development; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0006119 oxidative phosphorylation; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0006120 mitochondrial electron transport, NADH to ubiquinone; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0032501 multicellular organismal process; GO:0048513 animal organ development; GO:0097031 mitochondrial respiratory chain complex I biogenesis; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0022900 electron transport chain; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0070271 protein complex biogenesis; GO:0048856 anatomical structure development; GO:0033108 mitochondrial respiratory chain complex assembly; GO:0072359 circulatory system development; GO:0014706 striated muscle tissue development; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0016310 phosphorylation; GO:0048738 cardiac muscle tissue development; GO:0006725 cellular aromatic compound metabolic process; GO:0042773 ATP synthesis coupled electron transport; GO:0009259 ribonucleotide metabolic process; GO:0022904 respiratory electron transport chain; GO:0071704 organic substance metabolic process; GO:0032981 mitochondrial respiratory chain complex I assembly; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009119 ribonucleoside metabolic process; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0043623 cellular protein complex assembly; GO:0046034 ATP metabolic process; GO:0034622 cellular macromolecular complex assembly; GO:0048731 system development; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0045333 cellular respiration; GO:0006163 purine nucleotide metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0046128 purine ribonucleoside metabolic process; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:0071840 cellular component organization or biogenesis; GO:1901564 organonitrogen compound metabolic process; GO:0009123 nucleoside monophosphate metabolic process; ","GO:0016020 membrane; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0045271 respiratory chain complex I; GO:0044424 intracellular part; GO:0098798 mitochondrial protein complex; GO:0005747 mitochondrial respiratory chain complex I; GO:0005623 cell; GO:0044455 mitochondrial membrane part; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:1902494 catalytic complex; GO:0043209 myelin sheath; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0098803 respiratory chain complex; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005739 mitochondrion; GO:0005746 mitochondrial respiratory chain; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0030964 NADH dehydrogenase complex; GO:1990204 oxidoreductase complex; GO:0031975 envelope; GO:0043234 protein complex; GO:0031966 mitochondrial membrane; GO:0070469 respiratory chain; GO:0044444 cytoplasmic part; ","GO:0009055 electron carrier activity; GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:0051537 2 iron, 2 sulfur cluster binding; GO:0003954 NADH dehydrogenase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0051536 iron-sulfur cluster binding; GO:0043167 ion binding; GO:0050136 NADH dehydrogenase (quinone) activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; GO:0008137 NADH dehydrogenase (ubiquinone) activity; GO:0016491 oxidoreductase activity; GO:0051540 metal cluster binding; ","K03943","NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:1.6.5.3 1.6.99.3]","hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); ","IPR012336; ","Thioredoxin-like fold; \r"]
["P19474","E3 ubiquitin-protein ligase TRIM21 OS=Homo sapiens OX=9606 GN=TRIM21","TRIM21",54.169,17.753,12.8,6,7,6,0.912,0.988,0.862,1.078,1.069,1.092,1.173,0.0568,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0007166 cell surface receptor signaling pathway; GO:0051865 protein autoubiquitination; GO:0071345 cellular response to cytokine stimulus; GO:0032897 negative regulation of viral transcription; GO:0044237 cellular metabolic process; GO:0032088 negative regulation of NF-kappaB transcription factor activity; GO:0008152 metabolic process; GO:0065003 macromolecular complex assembly; GO:0044093 positive regulation of molecular function; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0031323 regulation of cellular metabolic process; GO:0010506 regulation of autophagy; GO:1903506 regulation of nucleic acid-templated transcription; GO:0010508 positive regulation of autophagy; GO:0032269 negative regulation of cellular protein metabolic process; GO:0051090 regulation of sequence-specific DNA binding transcription factor activity; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0051239 regulation of multicellular organismal process; GO:0051259 protein oligomerization; GO:0000209 protein polyubiquitination; GO:1903901 negative regulation of viral life cycle; GO:0009889 regulation of biosynthetic process; GO:0009896 positive regulation of catabolic process; GO:0046598 positive regulation of viral entry into host cell; GO:0051171 regulation of nitrogen compound metabolic process; GO:0006461 protein complex assembly; GO:0045787 positive regulation of cell cycle; GO:0045861 negative regulation of proteolysis; GO:0016567 protein ubiquitination; GO:0006950 response to stress; GO:0043900 regulation of multi-organism process; GO:0002376 immune system process; GO:0030162 regulation of proteolysis; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1903321 negative regulation of protein modification by small protein conjugation or removal; GO:1902186 regulation of viral release from host cell; GO:0046782 regulation of viral transcription; GO:0009890 negative regulation of biosynthetic process; GO:0032446 protein modification by small protein conjugation; GO:0031325 positive regulation of cellular metabolic process; GO:0031647 regulation of protein stability; GO:0043412 macromolecule modification; GO:0006955 immune response; GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity; GO:0031331 positive regulation of cellular catabolic process; GO:0071346 cellular response to interferon-gamma; GO:0044699 single-organism process; GO:0051253 negative regulation of RNA metabolic process; GO:0031400 negative regulation of protein modification process; GO:0060333 interferon-gamma-mediated signaling pathway; GO:0040013 negative regulation of locomotion; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0022607 cellular component assembly; GO:0046596 regulation of viral entry into host cell; GO:0051726 regulation of cell cycle; GO:0070887 cellular response to chemical stimulus; GO:0048525 negative regulation of viral process; GO:0010468 regulation of gene expression; GO:1903902 positive regulation of viral life cycle; GO:0043902 positive regulation of multi-organism process; GO:0071822 protein complex subunit organization; GO:0031326 regulation of cellular biosynthetic process; GO:0034097 response to cytokine; GO:0048522 positive regulation of cellular process; GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity; GO:0070647 protein modification by small protein conjugation or removal; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0090086 negative regulation of protein deubiquitination; GO:0006513 protein monoubiquitination; GO:1902679 negative regulation of RNA biosynthetic process; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0006952 defense response; GO:0036211 protein modification process; GO:0070271 protein complex biogenesis; GO:0016043 cellular component organization; GO:0090085 regulation of protein deubiquitination; GO:0032479 regulation of type I interferon production; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0071310 cellular response to organic substance; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0045087 innate immune response; GO:0071704 organic substance metabolic process; GO:0009987 cellular process; GO:0019221 cytokine-mediated signaling pathway; GO:0006355 regulation of transcription, DNA-templated; GO:0070206 protein trimerization; GO:0010629 negative regulation of gene expression; GO:0050792 regulation of viral process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0034341 response to interferon-gamma; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0031648 protein destabilization; GO:0043901 negative regulation of multi-organism process; GO:0043933 macromolecular complex subunit organization; GO:0048524 positive regulation of viral process; GO:1902187 negative regulation of viral release from host cell; GO:0051246 regulation of protein metabolic process; GO:0001817 regulation of cytokine production; GO:0051248 negative regulation of protein metabolic process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0040012 regulation of locomotion; GO:1903900 regulation of viral life cycle; GO:0007049 cell cycle; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0031410 cytoplasmic vesicle; GO:0000932 P-body; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0005776 autophagosome; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0035770 ribonucleoprotein granule; GO:0005773 vacuole; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0003723 RNA binding; GO:0003677 DNA binding; GO:0019787 ubiquitin-like protein transferase activity; GO:0043167 ion binding; GO:0005515 protein binding; GO:0008270 zinc ion binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0042802 identical protein binding; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0004842 ubiquitin-protein transferase activity; GO:0003676 nucleic acid binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0016740 transferase activity; ","K10651","TRIM21; tripartite motif-containing protein 21 [EC:2.3.2.27]","hsa05322 Systemic lupus erythematosus - Homo sapiens (human); ","IPR006574; IPR001841; IPR003613; IPR001870; IPR020457; IPR013320; IPR000315; IPR003877; IPR013083; IPR003879; ","\"SPRY-associated; Zinc finger, RING-type; U box domain; B30.2/SPRY domain; Zinc finger, B-box, chordata; Concanavalin A-like lectin/glucanase domain; B-box-type zinc finger; SPRY domain; Zinc finger, RING/FYVE/PHD-type; Butyrophylin-like; \"\r"]
["P19525","Interferon-induced, double-stranded RNA-activated protein kinase OS=Homo sapiens OX=9606 GN=EIF2AK2","EIF2AK2",62.094,7.5758,6.9,3,3,3,1.024,0.965,0.95,1.003,1.021,1.043,1.044,0.167,"cytoplasm\r","GO:0044700 single organism signaling; GO:0032872 regulation of stress-activated MAPK cascade; GO:0010941 regulation of cell death; GO:0010608 posttranscriptional regulation of gene expression; GO:0098542 defense response to other organism; GO:0002698 negative regulation of immune effector process; GO:0018212 peptidyl-tyrosine modification; GO:0031347 regulation of defense response; GO:1901224 positive regulation of NIK/NF-kappaB signaling; GO:0044237 cellular metabolic process; GO:0009607 response to biotic stimulus; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0008152 metabolic process; GO:0044093 positive regulation of molecular function; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0034249 negative regulation of cellular amide metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0051704 multi-organism process; GO:1900225 regulation of NLRP3 inflammasome complex assembly; GO:0051092 positive regulation of NF-kappaB transcription factor activity; GO:0080135 regulation of cellular response to stress; GO:0032874 positive regulation of stress-activated MAPK cascade; GO:0044415 evasion or tolerance of host defenses; GO:0048583 regulation of response to stimulus; GO:0033689 negative regulation of osteoblast proliferation; GO:0044260 cellular macromolecule metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0060548 negative regulation of cell death; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0016310 phosphorylation; GO:0009267 cellular response to starvation; GO:0072091 regulation of stem cell proliferation; GO:0001819 positive regulation of cytokine production; GO:0048519 negative regulation of biological process; GO:0051817 modification of morphology or physiology of other organism involved in symbiotic interaction; GO:1903706 regulation of hemopoiesis; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0075136 response to host; GO:0006986 response to unfolded protein; GO:0006950 response to stress; GO:0032101 regulation of response to external stimulus; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:1901576 organic substance biosynthetic process; GO:0034248 regulation of cellular amide metabolic process; GO:0009890 negative regulation of biosynthetic process; GO:0052572 response to host immune response; GO:0031325 positive regulation of cellular metabolic process; GO:0043412 macromolecule modification; GO:0006955 immune response; GO:0052200 response to host defenses; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0006796 phosphate-containing compound metabolic process; GO:0030968 endoplasmic reticulum unfolded protein response; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0009893 positive regulation of metabolic process; GO:0032642 regulation of chemokine production; GO:0046777 protein autophosphorylation; GO:0033674 positive regulation of kinase activity; GO:0048525 negative regulation of viral process; GO:0002832 negative regulation of response to biotic stimulus; GO:0045937 positive regulation of phosphate metabolic process; GO:0034097 response to cytokine; GO:0031326 regulation of cellular biosynthetic process; GO:0050687 negative regulation of defense response to virus; GO:0043043 peptide biosynthetic process; GO:0009636 response to toxic substance; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051607 defense response to virus; GO:0006351 transcription, DNA-templated; GO:0065009 regulation of molecular function; GO:0010998 regulation of translational initiation by eIF2 alpha phosphorylation; GO:0006952 defense response; GO:0036211 protein modification process; GO:0032722 positive regulation of chemokine production; GO:0009615 response to virus; GO:0043549 regulation of kinase activity; GO:0043069 negative regulation of programmed cell death; GO:0002831 regulation of response to biotic stimulus; GO:0035967 cellular response to topologically incorrect protein; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0051807 evasion or tolerance of defense response of other organism involved in symbiotic interaction; GO:1901566 organonitrogen compound biosynthetic process; GO:0051707 response to other organism; GO:0031669 cellular response to nutrient levels; GO:0045087 innate immune response; GO:0071704 organic substance metabolic process; GO:0006468 protein phosphorylation; GO:0043066 negative regulation of apoptotic process; GO:0043408 regulation of MAPK cascade; GO:0016032 viral process; GO:0023056 positive regulation of signaling; GO:0034641 cellular nitrogen compound metabolic process; GO:0010647 positive regulation of cell communication; GO:0009059 macromolecule biosynthetic process; GO:0031348 negative regulation of defense response; GO:0045595 regulation of cell differentiation; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0001932 regulation of protein phosphorylation; GO:0001934 positive regulation of protein phosphorylation; GO:0044249 cellular biosynthetic process; GO:0043901 negative regulation of multi-organism process; GO:0043085 positive regulation of catalytic activity; GO:0018193 peptidyl-amino acid modification; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:1902033 regulation of hematopoietic stem cell proliferation; GO:0051248 negative regulation of protein metabolic process; GO:0001817 regulation of cytokine production; GO:0010467 gene expression; GO:0042594 response to starvation; GO:0043604 amide biosynthetic process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0042981 regulation of apoptotic process; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0006518 peptide metabolic process; GO:0097659 nucleic acid-templated transcription; GO:0043555 regulation of translation in response to stress; GO:0008285 negative regulation of cell proliferation; GO:0030682 evasion or tolerance of host defense response; GO:0009605 response to external stimulus; GO:0035966 response to topologically incorrect protein; GO:0050690 regulation of defense response to virus by virus; GO:0051240 positive regulation of multicellular organismal process; GO:0032102 negative regulation of response to external stimulus; GO:0044003 modification by symbiont of host morphology or physiology; GO:0010562 positive regulation of phosphorus metabolic process; GO:0042327 positive regulation of phosphorylation; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0051347 positive regulation of transferase activity; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:1902036 regulation of hematopoietic stem cell differentiation; GO:0044413 avoidance of host defenses; GO:0051174 regulation of phosphorus metabolic process; GO:0018130 heterocycle biosynthetic process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0051090 regulation of sequence-specific DNA binding transcription factor activity; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0002682 regulation of immune system process; GO:1901362 organic cyclic compound biosynthetic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0051832 avoidance of defenses of other organism involved in symbiotic interaction; GO:0034976 response to endoplasmic reticulum stress; GO:0042127 regulation of cell proliferation; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0043067 regulation of programmed cell death; GO:0043558 regulation of translational initiation in response to stress; GO:0017148 negative regulation of translation; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:0051239 regulation of multicellular organismal process; GO:1903901 negative regulation of viral life cycle; GO:0050688 regulation of defense response to virus; GO:0032147 activation of protein kinase activity; GO:0019438 aromatic compound biosynthetic process; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0009966 regulation of signal transduction; GO:1902531 regulation of intracellular signal transduction; GO:1901222 regulation of NIK/NF-kappaB signaling; GO:0043900 regulation of multi-organism process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0071496 cellular response to external stimulus; GO:2000736 regulation of stem cell differentiation; GO:0045071 negative regulation of viral genome replication; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0031668 cellular response to extracellular stimulus; GO:0051247 positive regulation of protein metabolic process; GO:0006793 phosphorus metabolic process; GO:0048584 positive regulation of response to stimulus; GO:0050793 regulation of developmental process; GO:1901564 organonitrogen compound metabolic process; GO:0052173 response to defenses of other organism involved in symbiotic interaction; GO:1902533 positive regulation of intracellular signal transduction; GO:0044764 multi-organism cellular process; GO:0051834 evasion or tolerance of defenses of other organism involved in symbiotic interaction; GO:0035821 modification of morphology or physiology of other organism; GO:0033688 regulation of osteoblast proliferation; GO:0000186 activation of MAPKK activity; GO:0010646 regulation of cell communication; GO:0070302 regulation of stress-activated protein kinase signaling cascade; GO:0007154 cell communication; GO:0070304 positive regulation of stress-activated protein kinase signaling cascade; GO:0006412 translation; GO:0002697 regulation of immune effector process; GO:0030683 evasion or tolerance by virus of host immune response; GO:0070887 cellular response to chemical stimulus; GO:0010468 regulation of gene expression; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0020012 evasion or tolerance of host immune response; GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity; GO:0043603 cellular amide metabolic process; GO:0045069 regulation of viral genome replication; GO:0052564 response to immune response of other organism involved in symbiotic interaction; GO:0018108 peptidyl-tyrosine phosphorylation; GO:0002683 negative regulation of immune system process; GO:0016070 RNA metabolic process; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0043254 regulation of protein complex assembly; GO:0090304 nucleic acid metabolic process; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:2000026 regulation of multicellular organismal development; GO:0045859 regulation of protein kinase activity; GO:0034198 cellular response to amino acid starvation; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0006725 cellular aromatic compound metabolic process; GO:0002252 immune effector process; GO:0043405 regulation of MAP kinase activity; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044087 regulation of cellular component biogenesis; GO:0031324 negative regulation of cellular metabolic process; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0009991 response to extracellular stimulus; GO:1901532 regulation of hematopoietic progenitor cell differentiation; GO:0009987 cellular process; GO:0034620 cellular response to unfolded protein; GO:0050792 regulation of viral process; GO:0031401 positive regulation of protein modification process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0045860 positive regulation of protein kinase activity; GO:0051701 interaction with host; GO:0048518 positive regulation of biological process; GO:0019049 evasion or tolerance of host defenses by virus; GO:0051252 regulation of RNA metabolic process; GO:0051805 evasion or tolerance of immune response of other organism involved in symbiotic interaction; GO:0051246 regulation of protein metabolic process; GO:0006417 regulation of translation; GO:0006446 regulation of translational initiation; GO:0035455 response to interferon-alpha; GO:0009967 positive regulation of signal transduction; GO:0031667 response to nutrient levels; GO:0051128 regulation of cellular component organization; GO:0043410 positive regulation of MAPK cascade; GO:1903900 regulation of viral life cycle; GO:0019048 modulation by virus of host morphology or physiology; GO:0065007 biological regulation; ","GO:0005840 ribosome; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0043228 non-membrane-bounded organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:0048471 perinuclear region of cytoplasm; GO:1990904 ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0030529 intracellular ribonucleoprotein complex; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0019888 protein phosphatase regulator activity; GO:0004713 protein tyrosine kinase activity; GO:0005515 protein binding; GO:0004672 protein kinase activity; GO:0098772 molecular function regulator; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016301 kinase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003723 RNA binding; GO:0005524 ATP binding; GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity; GO:0003725 double-stranded RNA binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0032549 ribonucleoside binding; GO:0004715 non-membrane spanning protein tyrosine kinase activity; GO:0097367 carbohydrate derivative binding; GO:0030234 enzyme regulator activity; GO:0019208 phosphatase regulator activity; GO:0003676 nucleic acid binding; GO:0004674 protein serine/threonine kinase activity; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K16195","EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]","hsa05168 Herpes simplex infection - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); hsa05160 Hepatitis C - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa04217 Necroptosis - Homo sapiens (human); hsa05167 Kaposi's sarcoma-associated herpesvirus infection - Homo sapiens (human); hsa05203 Viral carcinogenesis - Homo sapiens (human); hsa05162 Measles - Homo sapiens (human); hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); hsa05164 Influenza A - Homo sapiens (human); ","IPR000719; IPR014720; IPR011009; ","Protein kinase domain; Double-stranded RNA-binding domain; Protein kinase-like domain; \r"]
["P19623","Spermidine synthase OS=Homo sapiens OX=9606 GN=SRM","SRM",33.824,30.968,21.9,5,5,5,0.903,0.96,0.99,1.084,1.056,1.015,1.106,0.038,"cytoplasm\r","GO:0044106 cellular amine metabolic process; GO:0008216 spermidine metabolic process; GO:0097164 ammonium ion metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0009058 biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:1901576 organic substance biosynthetic process; GO:0044237 cellular metabolic process; GO:0044249 cellular biosynthetic process; GO:0006576 cellular biogenic amine metabolic process; GO:0071704 organic substance metabolic process; GO:0042401 cellular biogenic amine biosynthetic process; GO:0006595 polyamine metabolic process; GO:0008152 metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006596 polyamine biosynthetic process; GO:0009309 amine biosynthetic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0008295 spermidine biosynthetic process; GO:0009987 cellular process; GO:0009308 amine metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:0042802 identical protein binding; GO:0004766 spermidine synthase activity; GO:0003824 catalytic activity; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0046983 protein dimerization activity; GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups; GO:0005515 protein binding; GO:0016740 transferase activity; ","K00797","speE; spermidine synthase [EC:2.5.1.16]","hsa00480 Glutathione metabolism - Homo sapiens (human); hsa00410 beta-Alanine metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00270 Cysteine and methionine metabolism - Homo sapiens (human); hsa00330 Arginine and proline metabolism - Homo sapiens (human); ","IPR029063; IPR030374; ","S-adenosyl-L-methionine-dependent methyltransferase; Polyamine biosynthesis  domain; \r"]
["P19634","Sodium/hydrogen exchanger 1 OS=Homo sapiens OX=9606 GN=SLC9A1","SLC9A1",90.762,4.6935,1.6,1,1,1,0.874,1.118,0.782,0.956,1.346,0.926,1.164,0.406,"plasma membrane\r",{"$cut":{"chars":17268,"head":"GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0051532 regulation of NFAT protein import into nucleus; GO:0009891 positive regulation of biosynthetic process; GO:0014742 positive regulation of muscle hypertrophy; GO:0030641 regulation of cellular pH; GO:0030004 cellular monovalent inorganic cation homeostasis; GO:0030203 glycosaminoglycan metabolic process; GO:0045927 positive regulation of growth; GO:0001558 regulation of cell growth; GO:0061337 cardiac conduction; GO:0008152 metabolic process; GO:0014743 regulation of muscle hypertrophy; GO:1901019 regulation of calcium ion transmembrane transporter activity; GO:0065003 macromolecular complex assembly; GO:0044093 positive regulation of molecular function; GO:0055065 metal ion homeostasis; GO:0044057 regulation of system process; GO:0051493 regulation of cytoskeleton organization; GO:0090559 regulation of membrane permeability; GO:0051716 cellular response to stimulus; GO:0071214 cellular response to abiotic stimulus; GO:0030307 positive regulation of cell growth; GO:0080090 regulation of primary metabolic process; GO:0060537 muscle tissue development; GO:0044763 single-organism cellular process; GO:0019932 second-messenger-mediated signaling; GO:0048870 cell motility; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0010243 response to organonitrogen compound; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:1901698 response to nitrogen compound; GO:1901021 positive regulation of calcium ion transmembrane transporter activity; GO:0051223 regulation of protein transport; GO:0032412 regulation of ion transmembrane transporter activity; GO:0060548 negative regulation of cell death; GO:0098662 inorganic cation transmembrane transport; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0042307 positive regulation of protein import into nucleus; GO:0072359 circulatory system development; GO:0044707 single-multicellular organism process; GO:0002028 regulation of sodium ion transport; GO:0034220 ion transmembrane transport; GO:0006885 regulation of pH; GO:0007006 mitochondrial membrane organization; GO:0030001 metal ion transport; GO:1901700 response to oxygen-containing compound; GO:0048519 negative regulation of biological process; GO:0042990 regulation of transcription factor import into nucleus; GO:0042493 response to drug; GO:0086003 cardiac muscle cell contraction; GO:0098659 inorganic cation import into cell; GO:0009889 regulation of biosynthetic process; GO:0070482 response to oxygen levels; GO:0010959 regulation of metal ion transport; GO:0061061 muscle structure development; GO:1902680 positive regulation of RNA biosynthetic process; GO:0050848 regulation of calcium-mediated signaling; GO:0051930 regulation of sensory perception of pain; GO:0032409 regulation of transporter activity; GO:0048878 chemical homeostasis; GO:0051928 positive regulation of calcium ion transport; GO:0006950 response to stress; GO:0051924 regulation of calcium ion transport; GO:0032970 regulation of actin filament-based process; GO:0010033 response to organic substance; GO:0010611 regulation of cardiac muscle hypertrophy; GO:0051492 regulation of stress fiber assembly; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:1900182 positive regulation of protein localization to nucleus; GO:0043502 regulation of muscle adaptation; GO:1904064 positive regulation of cation transmembrane transport; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0071870 cellular response to catecholamine stimulus; GO:0010447 response to acidic pH; GO:0040007 growth; GO:1903827 regulation of cellular protein localization; GO:0030048 actin filament-based movement; GO:0051533 positive regulation of NFAT protein import into nucleus; GO:0003012 muscle system process; GO:1903391 regulation of adherens junction organization; GO:0051674 localization of cell; GO:004"}},"GO:0016020 membrane; GO:0044421 extracellular region part; GO:0098857 membrane microdomain; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0090533 cation-transporting ATPase complex; GO:0044422 organelle part; GO:0014704 intercalated disc; GO:0030315 T-tubule; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0098590 plasma membrane region; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0098589 membrane region; GO:0030027 lamellipodium; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0045177 apical part of cell; GO:0005789 endoplasmic reticulum membrane; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0031252 cell leading edge; GO:0042995 cell projection; GO:0031226 intrinsic component of plasma membrane; GO:0070161 anchoring junction; GO:0031981 nuclear lumen; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0042383 sarcolemma; GO:0043230 extracellular organelle; GO:0016323 basolateral plasma membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0016324 apical plasma membrane; GO:0071944 cell periphery; GO:0044291 cell-cell contact zone; GO:0030054 cell junction; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005911 cell-cell junction; GO:0098533 ATPase dependent transmembrane transport complex; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0044464 cell part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0005912 adherens junction; GO:0048471 perinuclear region of cytoplasm; GO:0045121 membrane raft; GO:1990351 transporter complex; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:1902495 transmembrane transporter complex; GO:0016021 integral component of membrane; GO:0043226 organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0044432 endoplasmic reticulum part; GO:1904949 ATPase complex; GO:0009986 cell surface; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0019903 protein phosphatase binding; GO:0015299 solute:proton antiporter activity; GO:0022892 substrate-specific transporter activity; GO:0015077 monovalent inorganic cation transmembrane transporter activity; GO:0005515 protein binding; GO:0048306 calcium-dependent protein binding; GO:0015078 hydrogen ion transmembrane transporter activity; GO:0015297 antiporter activity; GO:1902936 phosphatidylinositol bisphosphate binding; GO:0022891 substrate-specific transmembrane transporter activity; GO:0099516 ion antiporter activity; GO:0022821 potassium ion antiporter activity; GO:0005451 monovalent cation:proton antiporter activity; GO:0032947 protein complex scaffold; GO:0046873 metal ion transmembrane transporter activity; GO:0015385 sodium:proton antiporter activity; GO:0005546 phosphatidylinositol-4,5-bisphosphate binding; GO:0005488 binding; GO:0035091 phosphatidylinositol binding; GO:0015491 cation:cation antiporter activity; GO:0008289 lipid binding; GO:0043168 anion binding; GO:0030346 protein phosphatase 2B binding; GO:0019902 phosphatase binding; GO:0022890 inorganic cation transmembrane transporter activity; GO:0015081 sodium ion transmembrane transporter activity; GO:0005215 transporter activity; GO:0015291 secondary active transmembrane transporter activity; GO:0022804 active transmembrane transporter activity; GO:0015298 solute:cation antiporter activity; GO:1901981 phosphatidylinositol phosphate binding; GO:0030674 protein binding, bridging; GO:0015075 ion transmembrane transporter activity; GO:0043167 ion binding; GO:0005516 calmodulin binding; GO:0015079 potassium ion transmembrane transporter activity; GO:0015386 potassium:proton antiporter activity; GO:0086040 sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential; GO:0005543 phospholipid binding; GO:0060090 binding, bridging; GO:0005198 structural molecule activity; GO:0019899 enzyme binding; GO:0008324 cation transmembrane transporter activity; GO:0022857 transmembrane transporter activity; ","K05742","SLC9A1; solute carrier family 9 (sodium/hydrogen exchanger), member 1","hsa04260 Cardiac muscle contraction - Homo sapiens (human); hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human); hsa04972 Pancreatic secretion - Homo sapiens (human); hsa04371 Apelin signaling pathway - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa04024 cAMP signaling pathway - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human); hsa04976 Bile secretion - Homo sapiens (human); hsa04971 Gastric acid secretion - Homo sapiens (human); hsa04970 Salivary secretion - Homo sapiens (human); ","IPR032103; IPR006153; ","\"Sodium/hydrogen exchanger, regulatory region; Cation/H+ exchanger; \"\r"]
["P19652","Alpha-1-acid glycoprotein 2 OS=Homo sapiens OX=9606 GN=ORM2","ORM2",23.602,5.7254,9.5,2,4,2,1.042,0.891,0.963,0.927,1.03,1.081,1.049,0.496,"extracellular\r","GO:0045321 leukocyte activation; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0002576 platelet degranulation; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0051234 establishment of localization; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0002443 leukocyte mediated immunity; GO:0006950 response to stress; GO:0016192 vesicle-mediated transport; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0002376 immune system process; GO:0043312 neutrophil degranulation; GO:0002263 cell activation involved in immune response; GO:0002444 myeloid leukocyte mediated immunity; GO:0002366 leukocyte activation involved in immune response; GO:0006810 transport; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0050789 regulation of biological process; GO:0006953 acute-phase response; GO:0032940 secretion by cell; GO:0002526 acute inflammatory response; GO:0006954 inflammatory response; GO:0001775 cell activation; GO:0002682 regulation of immune system process; GO:0043299 leukocyte degranulation; GO:0006952 defense response; GO:0006955 immune response; GO:0051179 localization; GO:0006887 exocytosis; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0042582 azurophil granule; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0072562 blood microparticle; GO:0060205 cytoplasmic vesicle lumen; GO:0035580 specific granule lumen; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0042581 specific granule; GO:0005773 vacuole; GO:0031093 platelet alpha granule lumen; GO:0031091 platelet alpha granule; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ",null,"K17308",null,null,"IPR000566; IPR012674; IPR011038; ","Lipocalin/cytosolic fatty-acid binding domain; Calycin; Calycin-like; \r"]
["P19823","Inter-alpha-trypsin inhibitor heavy chain H2 OS=Homo sapiens OX=9606 GN=ITIH2","ITIH2",106.46,114.18,20.8,20,51,20,1.006,0.984,0.974,1.012,1.026,0.993,1.023,0.172,"extracellular\r","GO:0050794 regulation of cellular process; GO:0010951 negative regulation of endopeptidase activity; GO:0060255 regulation of macromolecule metabolic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0051346 negative regulation of hydrolase activity; GO:0030203 glycosaminoglycan metabolic process; GO:0071704 organic substance metabolic process; GO:0010466 negative regulation of peptidase activity; GO:0008152 metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0043170 macromolecule metabolic process; GO:0006022 aminoglycan metabolic process; GO:0030212 hyaluronan metabolic process; GO:0052548 regulation of endopeptidase activity; GO:0045861 negative regulation of proteolysis; GO:1903510 mucopolysaccharide metabolic process; GO:0080090 regulation of primary metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0030162 regulation of proteolysis; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0009892 negative regulation of metabolic process; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0051246 regulation of protein metabolic process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0065009 regulation of molecular function; GO:0051248 negative regulation of protein metabolic process; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0052547 regulation of peptidase activity; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0072562 blood microparticle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:0004867 serine-type endopeptidase inhibitor activity; GO:0030234 enzyme regulator activity; GO:0030414 peptidase inhibitor activity; GO:0061134 peptidase regulator activity; GO:0061135 endopeptidase regulator activity; GO:0098772 molecular function regulator; GO:0004857 enzyme inhibitor activity; GO:0004866 endopeptidase inhibitor activity; ","K19015",null,null,"IPR010600; IPR013694; IPR002035; ","\"Inter-alpha-trypsin inhibitor heavy chain, C-terminal; VIT domain; von Willebrand factor, type A; \"\r"]
["P19827","Inter-alpha-trypsin inhibitor heavy chain H1 OS=Homo sapiens OX=9606 GN=ITIH1","ITIH1",101.39,282.9,24.1,17,49,17,0.981,0.97,0.957,1.031,1.031,1.035,1.065,0.000979,"endoplasmic reticulum\r","GO:0050794 regulation of cellular process; GO:0010951 negative regulation of endopeptidase activity; GO:0060255 regulation of macromolecule metabolic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0051346 negative regulation of hydrolase activity; GO:0030203 glycosaminoglycan metabolic process; GO:0071704 organic substance metabolic process; GO:0010466 negative regulation of peptidase activity; GO:0008152 metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0043170 macromolecule metabolic process; GO:0006022 aminoglycan metabolic process; GO:0030212 hyaluronan metabolic process; GO:0052548 regulation of endopeptidase activity; GO:0045861 negative regulation of proteolysis; GO:1903510 mucopolysaccharide metabolic process; GO:0080090 regulation of primary metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0030162 regulation of proteolysis; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0009892 negative regulation of metabolic process; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0051246 regulation of protein metabolic process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0065009 regulation of molecular function; GO:0051248 negative regulation of protein metabolic process; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0052547 regulation of peptidase activity; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0072562 blood microparticle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:0004867 serine-type endopeptidase inhibitor activity; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0043167 ion binding; GO:0030414 peptidase inhibitor activity; GO:0061134 peptidase regulator activity; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0061135 endopeptidase regulator activity; GO:0005509 calcium ion binding; GO:0098772 molecular function regulator; GO:0004857 enzyme inhibitor activity; GO:0004866 endopeptidase inhibitor activity; ","K19014",null,null,"IPR010600; IPR013694; IPR002035; ","\"Inter-alpha-trypsin inhibitor heavy chain, C-terminal; VIT domain; von Willebrand factor, type A; \"\r"]
["P19838","Nuclear factor NF-kappa-B p105 subunit OS=Homo sapiens OX=9606 GN=NFKB1","NFKB1",105.35,28.991,10,7,8,7,1.106,1.064,0.999,1.033,0.876,0.943,0.9,0.13,"cytoplasm\r","GO:0044700 single organism signaling; GO:0010744 positive regulation of macrophage derived foam cell differentiation; GO:0035094 response to nicotine; GO:0010941 regulation of cell death; GO:0032885 regulation of polysaccharide biosynthetic process; GO:0032371 regulation of sterol transport; GO:0009891 positive regulation of biosynthetic process; GO:0070555 response to interleukin-1; GO:0031347 regulation of defense response; GO:0044237 cellular metabolic process; GO:0009607 response to biotic stimulus; GO:0008152 metabolic process; GO:0044093 positive regulation of molecular function; GO:0090263 positive regulation of canonical Wnt signaling pathway; GO:0051051 negative regulation of transport; GO:0051716 cellular response to stimulus; GO:0071214 cellular response to abiotic stimulus; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0060828 regulation of canonical Wnt signaling pathway; GO:0043086 negative regulation of catalytic activity; GO:0051704 multi-organism process; GO:0071396 cellular response to lipid; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0000165 MAPK cascade; GO:0032375 negative regulation of cholesterol transport; GO:0010243 response to organonitrogen compound; GO:0051092 positive regulation of NF-kappaB transcription factor activity; GO:0002223 stimulatory C-type lectin receptor signaling pathway; GO:0032768 regulation of monooxygenase activity; GO:0046890 regulation of lipid biosynthetic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:1901698 response to nitrogen compound; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0060548 negative regulation of cell death; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0016310 phosphorylation; GO:0043255 regulation of carbohydrate biosynthetic process; GO:0042036 negative regulation of cytokine biosynthetic process; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0050728 negative regulation of inflammatory response; GO:0001819 positive regulation of cytokine production; GO:1901700 response to oxygen-containing compound; GO:0071354 cellular response to interleukin-6; GO:0048519 negative regulation of biological process; GO:0045892 negative regulation of transcription, DNA-templated; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0038093 Fc receptor signaling pathway; GO:0050778 positive regulation of immune response; GO:0071359 cellular response to dsRNA; GO:0023014 signal transduction by protein phosphorylation; GO:0006950 response to stress; GO:0032496 response to lipopolysaccharide; GO:0010884 positive regulation of lipid storage; GO:0032101 regulation of response to external stimulus; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0002263 cell activation involved in immune response; GO:1901576 organic substance biosynthetic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0045055 regulated exocytosis; GO:0009890 negative regulation of biosynthetic process; GO:0010883 regulation of lipid storage; GO:0031325 positive regulation of cellular metabolic process; GO:0071219 cellular response to molecule of bacterial origin; GO:0046137 negative regulation of vitamin metabolic process; GO:0030177 positive regulation of Wnt signaling pathway; GO:0043412 macromolecule modification; GO:0006955 immune response; GO:0030656 regulation of vitamin metabolic process; GO:0071316 cellular response to nicotine; GO:0032372 negative regulation of sterol transport; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0051253 negative regulation of RNA metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0031098 stress-activated protein kinase signaling cascade; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:1901653 cellular response to peptide; GO:0009893 positive regulation of metabolic process; GO:0050810 regulation of steroid biosynthetic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0006915 apoptotic process; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0051055 negative regulation of lipid biosynthetic process; GO:0045833 negative regulation of lipid metabolic process; GO:0042035 regulation of cytokine biosynthetic process; GO:0045083 negative regulation of interleukin-12 biosynthetic process; GO:0034097 response to cytokine; GO:0031326 regulation of cellular biosynthetic process; GO:0002237 response to molecule of bacterial origin; GO:0032769 negative regulation of monooxygenase activity; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0071417 cellular response to organonitrogen compound; GO:0006351 transcription, DNA-templated; GO:0032940 secretion by cell; GO:0006954 inflammatory response; GO:1902679 negative regulation of RNA biosynthetic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0006952 defense response; GO:0036211 protein modification process; GO:1900127 positive regulation of hyaluronan biosynthetic process; GO:0071260 cellular response to mechanical stimulus; GO:0043069 negative regulation of programmed cell death; GO:0032479 regulation of type I interferon production; GO:0060255 regulation of macromolecule metabolic process; GO:0032368 regulation of lipid transport; GO:0071310 cellular response to organic substance; GO:0051707 response to other organism; GO:0045087 innate immune response; GO:0071704 organic substance metabolic process; GO:0033993 response to lipid; GO:0009612 response to mechanical stimulus; GO:0006468 protein phosphorylation; GO:0051354 negative regulation of oxidoreductase activity; GO:0043066 negative regulation of apoptotic process; GO:0023056 positive regulation of signaling; GO:0002757 immune response-activating signal transduction; GO:0034641 cellular nitrogen compound metabolic process; GO:0010647 positive regulation of cell communication; GO:0009059 macromolecule biosynthetic process; GO:0031348 negative regulation of defense response; GO:0045595 regulation of cell differentiation; GO:0006355 regulation of transcription, DNA-templated; GO:0035556 intracellular signal transduction; GO:0010629 negative regulation of gene expression; GO:0051049 regulation of transport; GO:0010956 negative regulation of calcidiol 1-monooxygenase activity; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0032881 regulation of polysaccharide metabolic process; GO:0044249 cellular biosynthetic process; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0050852 T cell receptor signaling pathway; GO:1901701 cellular response to oxygen-containing compound; GO:0070741 response to interleukin-6; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0008219 cell death; GO:0010894 negative regulation of steroid biosynthetic process; GO:0071495 cellular response to endogenous stimulus; GO:0006366 transcription from RNA polymerase II promoter; GO:0002684 positive regulation of immune system process; GO:0038095 Fc-epsilon receptor signaling pathway; GO:0050727 regulation of inflammatory response; GO:0001817 regulation of cytokine production; GO:0051248 negative regulation of protein metabolic process; GO:0010467 gene expression; GO:0031327 negative regulation of cellular biosynthetic process; GO:0042981 regulation of apoptotic process; GO:2000628 regulation of miRNA metabolic process; GO:0032481 positive regulation of type I interferon production; GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0002220 innate immune response activating cell surface receptor signaling pathway; GO:0007166 cell surface receptor signaling pathway; GO:0097659 nucleic acid-templated transcription; GO:0019216 regulation of lipid metabolic process; GO:0031293 membrane protein intracellular domain proteolysis; GO:0071345 cellular response to cytokine stimulus; GO:0009605 response to external stimulus; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0032102 negative regulation of response to external stimulus; GO:1902931 negative regulation of alcohol biosynthetic process; GO:0009719 response to endogenous stimulus; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:1901652 response to peptide; GO:0010957 negative regulation of vitamin D biosynthetic process; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0014070 response to organic cyclic compound; GO:0002443 leukocyte mediated immunity; GO:0018130 heterocycle biosynthetic process; GO:0002758 innate immune response-activating signal transduction; GO:0045893 positive regulation of transcription, DNA-templated; GO:0000122 negative regulation of transcription from RNA polymerase II promoter; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0051341 regulation of oxidoreductase activity; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0051090 regulation of sequence-specific DNA binding transcription factor activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0002682 regulation of immune system process; GO:0051094 positive regulation of developmental process; GO:2000630 positive regulation of miRNA metabolic process; GO:0071312 cellular response to alkaloid; GO:1901362 organic cyclic compound biosynthetic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0002283 neutrophil activation involved in immune response; GO:0009628 response to abiotic stimulus; GO:0044267 cellular protein metabolic process; GO:0043067 regulation of programmed cell death; GO:0043279 response to alkaloid; GO:0019218 regulation of steroid metabolic process; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:1902930 regulation of alcohol biosynthetic process; GO:0060556 regulation of vitamin D biosynthetic process; GO:0051239 regulation of multicellular organismal process; GO:0045597 positive regulation of cell differentiation; GO:0035994 response to muscle stretch; GO:0031349 positive regulation of defense response; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0019438 aromatic compound biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0051171 regulation of nitrogen compound metabolic process; GO:0009966 regulation of signal transduction; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0009617 response to bacterium; GO:0038061 NIK/NF-kappaB signaling; GO:0002253 activation of immune response; GO:0051254 positive regulation of RNA metabolic process; GO:0016192 vesicle-mediated transport; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0071407 cellular response to organic cyclic compound; GO:0071496 cellular response to external stimulus; GO:0044238 primary metabolic process; GO:0006109 regulation of carbohydrate metabolic process; GO:0009892 negative regulation of metabolic process; GO:0006793 phosphorus metabolic process; GO:0030111 regulation of Wnt signaling pathway; GO:0045075 regulation of interleukin-12 biosynthetic process; GO:0001775 cell activation; GO:0007249 I-kappaB kinase/NF-kappaB signaling; GO:0012501 programmed cell death; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:0031328 positive regulation of cellular biosynthetic process; GO:0050793 regulation of developmental process; GO:0006887 exocytosis; GO:0045913 positive regulation of carbohydrate metabolic process; GO:0051241 negative regulation of multicellular organismal process; GO:0033619 membrane protein proteolysis; GO:0001818 negative regulation of cytokine production; GO:0051234 establishment of localization; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0045088 regulation of innate immune response; GO:1900125 regulation of hyaluronan biosynthetic process; GO:0060558 regulation of calcidiol 1-monooxygenase activity; GO:0070887 cellular response to chemical stimulus; GO:0050851 antigen receptor-mediated signaling pathway; GO:0002274 myeloid leukocyte activation; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0010468 regulation of gene expression; GO:0032695 negative regulation of interleukin-12 production; GO:0032369 negative regulation of lipid transport; GO:0010743 regulation of macrophage derived foam cell differentiation; GO:0002446 neutrophil mediated immunity; GO:0043331 response to dsRNA; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity; GO:0032374 regulation of cholesterol transport; GO:0016070 RNA metabolic process; GO:0045939 negative regulation of steroid metabolic process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0090304 nucleic acid metabolic process; GO:0043434 response to peptide hormone; GO:1901699 cellular response to nitrogen compound; GO:0032870 cellular response to hormone stimulus; GO:0019222 regulation of metabolic process; GO:0043299 leukocyte degranulation; GO:0002218 activation of innate immune response; GO:0006725 cellular aromatic compound metabolic process; GO:0071222 cellular response to lipopolysaccharide; GO:0002252 immune effector process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0071347 cellular response to interleukin-1; GO:0031324 negative regulation of cellular metabolic process; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0071216 cellular response to biotic stimulus; GO:0071375 cellular response to peptide hormone stimulus; GO:0006508 proteolysis; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0051403 stress-activated MAPK cascade; GO:0045089 positive regulation of innate immune response; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0043312 neutrophil degranulation; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0051246 regulation of protein metabolic process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0009967 positive regulation of signal transduction; GO:0009725 response to hormone; GO:0032655 regulation of interleukin-12 production; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0044446 intracellular organelle part; GO:0033256 I-kappaB/NF-kappaB complex; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0035580 specific granule lumen; GO:0042581 specific granule; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding; GO:0001158 enhancer sequence-specific DNA binding; GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding; GO:0003690 double-stranded DNA binding; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:0003682 chromatin binding; GO:0035326 enhancer binding; GO:0003700 transcription factor activity, sequence-specific DNA binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0000975 regulatory region DNA binding; GO:0008092 cytoskeletal protein binding; GO:0042802 identical protein binding; GO:0005488 binding; GO:0042805 actinin binding; GO:0001071 nucleic acid binding transcription factor activity; GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding; GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding; GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding; GO:0003677 DNA binding; GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding; GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding; GO:0046982 protein heterodimerization activity; GO:0000976 transcription regulatory region sequence-specific DNA binding; GO:0001012 RNA polymerase II regulatory region DNA binding; GO:1990837 sequence-specific double-stranded DNA binding; GO:0043565 sequence-specific DNA binding; GO:0001067 regulatory region nucleic acid binding; GO:0044212 transcription regulatory region DNA binding; GO:0042803 protein homodimerization activity; GO:0003676 nucleic acid binding; GO:0008134 transcription factor binding; ","K02580","NFKB1; nuclear factor NF-kappa-B p105 subunit","hsa05152 Tuberculosis - Homo sapiens (human); hsa05221 Acute myeloid leukemia - Homo sapiens (human); hsa04625 C-type lectin receptor signaling pathway - Homo sapiens (human); hsa04662 B cell receptor signaling pathway - Homo sapiens (human); hsa05220 Chronic myeloid leukemia - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa04014 Ras signaling pathway - Homo sapiens (human); hsa05222 Small cell lung cancer - Homo sapiens (human); hsa05162 Measles - Homo sapiens (human); hsa05166 HTLV-I infection - Homo sapiens (human); hsa05206 MicroRNAs in cancer - Homo sapiens (human); hsa05131 Shigellosis - Homo sapiens (human); hsa04931 Insulin resistance - Homo sapiens (human); hsa05145 Toxoplasmosis - Homo sapiens (human); hsa05164 Influenza A - Homo sapiens (human); hsa04920 Adipocytokine signaling pathway - Homo sapiens (human); hsa04380 Osteoclast differentiation - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa04071 Sphingolipid signaling pathway - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa04933 AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human); hsa04659 Th17 cell differentiation - Homo sapiens (human); hsa05321 Inflammatory bowel disease (IBD) - Homo sapiens (human); hsa04211 Longevity regulating pathway - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa04917 Prolactin signaling pathway - Homo sapiens (human); hsa05161 Hepatitis B - Homo sapiens (human); hsa05215 Prostate cancer - Homo sapiens (human); hsa04064 NF-kappa B signaling pathway - Homo sapiens (human); hsa05120 Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human); hsa05142 Chagas disease (American trypanosomiasis) - Homo sapiens (human); hsa05132 Salmonella infection - Homo sapiens (human); hsa04620 Toll-like receptor signaling pathway - Homo sapiens (human); hsa04218 Cellular senescence - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); hsa05168 Herpes simplex infection - Homo sapiens (human); hsa04210 Apoptosis - Homo sapiens (human); hsa04722 Neurotrophin signaling pathway - Homo sapiens (human); hsa05160 Hepatitis C - Homo sapiens (human); hsa05140 Leishmaniasis - Homo sapiens (human); hsa05167 Kaposi's sarcoma-associated herpesvirus infection - Homo sapiens (human); hsa04024 cAMP signaling pathway - Homo sapiens (human); hsa01523 Antifolate resistance - Homo sapiens (human); hsa05134 Legionellosis - Homo sapiens (human); hsa04010 MAPK signaling pathway - Homo sapiens (human); hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human); hsa05030 Cocaine addiction - Homo sapiens (human); hsa04660 T cell receptor signaling pathway - Homo sapiens (human); hsa04658 Th1 and Th2 cell differentiation - Homo sapiens (human); hsa04062 Chemokine signaling pathway - Homo sapiens (human); hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human); hsa04657 IL-17 signaling pathway - Homo sapiens (human); hsa04066 HIF-1 signaling pathway - Homo sapiens (human); hsa05146 Amoebiasis - Homo sapiens (human); hsa04668 TNF signaling pathway - Homo sapiens (human); hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human); hsa05203 Viral carcinogenesis - Homo sapiens (human); hsa04623 Cytosolic DNA-sensing pathway - Homo sapiens (human); hsa05133 Pertussis - Homo sapiens (human); hsa04622 RIG-I-like receptor signaling pathway - Homo sapiens (human); hsa04926 Relaxin signaling pathway - Homo sapiens (human); hsa05212 Pancreatic cancer - Homo sapiens (human); ","IPR008967; IPR014756; IPR032397; IPR033926; IPR011029; IPR002909; IPR000488; IPR013783; IPR020683; IPR011539; ","\"p53-like transcription factor, DNA-binding; Immunoglobulin E-set; Rel homology dimerisation domain; NFkappaB IPT domain; Death-like domain; IPT domain; Death domain; Immunoglobulin-like fold; Ankyrin repeat-containing domain; Rel homology domain (RHD), DNA-binding domain; \"\r"]
["P19878","Neutrophil cytosol factor 2 OS=Homo sapiens OX=9606 GN=NCF2","NCF2",59.761,10.291,8.7,4,4,4,0.807,0.837,0.889,1.157,1.162,1.135,1.364,0.000438,"cytoplasm\r","GO:0044700 single organism signaling; GO:0050794 regulation of cellular process; GO:0006801 superoxide metabolic process; GO:0065008 regulation of biological quality; GO:0007166 cell surface receptor signaling pathway; GO:0045454 cell redox homeostasis; GO:1901700 response to oxygen-containing compound; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0045087 innate immune response; GO:0042592 homeostatic process; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0007154 cell communication; GO:0072593 reactive oxygen species metabolic process; GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I; GO:0006979 response to oxidative stress; GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0009987 cellular process; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0051716 cellular response to stimulus; GO:0006950 response to stress; GO:0055114 oxidation-reduction process; GO:0048002 antigen processing and presentation of peptide antigen; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:0000302 response to reactive oxygen species; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0019725 cellular homeostasis; GO:0002376 immune system process; GO:0023052 signaling; GO:0042554 superoxide anion generation; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0019882 antigen processing and presentation; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0044710 single-organism metabolic process; GO:0006968 cellular defense response; GO:0045730 respiratory burst; GO:0006952 defense response; GO:0048010 vascular endothelial growth factor receptor signaling pathway; GO:0006955 immune response; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0032010 phagolysosome; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:0030141 secretory granule; GO:0005767 secondary lysosome; GO:0030139 endocytic vesicle; GO:0043020 NADPH oxidase complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0031226 intrinsic component of plasma membrane; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0045335 phagocytic vesicle; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0001669 acrosomal vesicle; GO:1990204 oxidoreductase complex; GO:0005773 vacuole; GO:0097223 sperm part; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0031267 small GTPase binding; GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:0017048 Rho GTPase binding; GO:0048365 Rac GTPase binding; GO:0005515 protein binding; GO:0016175 superoxide-generating NADPH oxidase activity; GO:0016491 oxidoreductase activity; GO:0009055 electron carrier activity; GO:0017016 Ras GTPase binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor; GO:0008022 protein C-terminus binding; GO:0051020 GTPase binding; GO:0019899 enzyme binding; ","K08010","NCF2; neutrophil cytosolic factor 2","hsa04670 Leukocyte transendothelial migration - Homo sapiens (human); hsa04380 Osteoclast differentiation - Homo sapiens (human); hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); hsa05140 Leishmaniasis - Homo sapiens (human); ","IPR000270; IPR001452; IPR011990; IPR013026; ","PB1 domain; SH3 domain; Tetratricopeptide-like helical domain; Tetratricopeptide repeat-containing domain; \r"]
["P19957","Elafin OS=Homo sapiens OX=9606 GN=PI3","PI3",12.269,2.1841,6.8,1,1,1,0.5,0.562,0.487,1.459,1.536,1.404,2.84,3.69e-05,"extracellular\r","GO:0022414 reproductive process; GO:0031424 keratinization; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0009607 response to biotic stimulus; GO:0009913 epidermal cell differentiation; GO:0009605 response to external stimulus; GO:0010466 negative regulation of peptidase activity; GO:0008544 epidermis development; GO:0032502 developmental process; GO:0052548 regulation of endopeptidase activity; GO:0060429 epithelium development; GO:0043588 skin development; GO:0030216 keratinocyte differentiation; GO:0009888 tissue development; GO:0080090 regulation of primary metabolic process; GO:0019730 antimicrobial humoral response; GO:0070268 cornification; GO:0019953 sexual reproduction; GO:0044763 single-organism cellular process; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051704 multi-organism process; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0007620 copulation; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0052547 regulation of peptidase activity; GO:0048856 anatomical structure development; GO:0030855 epithelial cell differentiation; GO:0050794 regulation of cellular process; GO:0000003 reproduction; GO:0044707 single-multicellular organism process; GO:0010951 negative regulation of endopeptidase activity; GO:0060255 regulation of macromolecule metabolic process; GO:0006959 humoral immune response; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0051346 negative regulation of hydrolase activity; GO:0030154 cell differentiation; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0045861 negative regulation of proteolysis; GO:0048731 system development; GO:0002376 immune system process; GO:0030162 regulation of proteolysis; GO:0009892 negative regulation of metabolic process; GO:0007618 mating; GO:0008219 cell death; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0044703 multi-organism reproductive process; GO:0051248 negative regulation of protein metabolic process; GO:0012501 programmed cell death; GO:0006955 immune response; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0031012 extracellular matrix; GO:0001533 cornified envelope; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0005578 proteinaceous extracellular matrix; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0004867 serine-type endopeptidase inhibitor activity; GO:0030234 enzyme regulator activity; GO:0030414 peptidase inhibitor activity; GO:0061134 peptidase regulator activity; GO:0061135 endopeptidase regulator activity; GO:0098772 molecular function regulator; GO:0004857 enzyme inhibitor activity; GO:0004866 endopeptidase inhibitor activity; ",{"$nulls":3},"IPR008197; ","WAP-type 'four-disulfide core' domain; \r"]
["P19971","Thymidine phosphorylase OS=Homo sapiens OX=9606 GN=TYMP","TYMP",49.955,133,35.9,14,40,14,0.738,0.742,0.76,1.272,1.233,1.223,1.664,2.24e-06,"nucleus\r","GO:0046135 pyrimidine nucleoside catabolic process; GO:0009116 nucleoside metabolic process; GO:0001568 blood vessel development; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0009163 nucleoside biosynthetic process; GO:0043174 nucleoside salvage; GO:0044237 cellular metabolic process; GO:0009605 response to external stimulus; GO:0001525 angiogenesis; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0046134 pyrimidine nucleoside biosynthetic process; GO:0006213 pyrimidine nucleoside metabolic process; GO:1901361 organic cyclic compound catabolic process; GO:0072527 pyrimidine-containing compound metabolic process; GO:0048514 blood vessel morphogenesis; GO:0032502 developmental process; GO:0018130 heterocycle biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0001944 vasculature development; GO:1901360 organic cyclic compound metabolic process; GO:0032501 multicellular organismal process; GO:0006935 chemotaxis; GO:0006206 pyrimidine nucleobase metabolic process; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0072529 pyrimidine-containing compound catabolic process; GO:0042221 response to chemical; GO:0043094 cellular metabolic compound salvage; GO:0044710 single-organism metabolic process; GO:0009112 nucleobase metabolic process; GO:0042330 taxis; GO:0040011 locomotion; GO:1901657 glycosyl compound metabolic process; GO:0048856 anatomical structure development; GO:1901362 organic cyclic compound biosynthetic process; GO:0072359 circulatory system development; GO:0044707 single-multicellular organism process; GO:0006725 cellular aromatic compound metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0072528 pyrimidine-containing compound biosynthetic process; GO:0009653 anatomical structure morphogenesis; GO:0044270 cellular nitrogen compound catabolic process; GO:0030154 cell differentiation; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:1901135 carbohydrate derivative metabolic process; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0034655 nucleobase-containing compound catabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0009987 cellular process; GO:0044711 single-organism biosynthetic process; GO:0043097 pyrimidine nucleoside salvage; GO:0048731 system development; GO:0044712 single-organism catabolic process; GO:1901658 glycosyl compound catabolic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:1901136 carbohydrate derivative catabolic process; GO:0072358 cardiovascular system development; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:1901565 organonitrogen compound catabolic process; GO:0008655 pyrimidine-containing compound salvage; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0044767 single-organism developmental process; GO:1901659 glycosyl compound biosynthetic process; GO:0009164 nucleoside catabolic process; GO:0009056 catabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0046700 heterocycle catabolic process; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:0008083 growth factor activity; GO:0016763 transferase activity, transferring pentosyl groups; GO:0009032 thymidine phosphorylase activity; GO:0016758 transferase activity, transferring hexosyl groups; GO:0005102 receptor binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0004645 phosphorylase activity; GO:0016154 pyrimidine-nucleoside phosphorylase activity; GO:0016757 transferase activity, transferring glycosyl groups; GO:0005515 protein binding; GO:0016740 transferase activity; ","K00758","deoA; thymidine phosphorylase [EC:2.4.2.4]","hsa00983 Drug metabolism - other enzymes - Homo sapiens (human); hsa05219 Bladder cancer - Homo sapiens (human); hsa00240 Pyrimidine metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR017459; IPR000312; IPR013102; ","\"Glycosyl transferase family 3, N-terminal domain; Glycosyl transferase, family 3; Pyrimidine nucleoside phosphorylase, C-terminal; \"\r"]
["P20020","Plasma membrane calcium-transporting ATPase 1 OS=Homo sapiens OX=9606 GN=ATP2B1","ATP2B1",138.75,7.8025,10.7,10,11,4,1.045,1.038,0.974,0.889,1.054,1.067,0.985,0.785,"plasma membrane\r","GO:0065008 regulation of biological quality; GO:0072503 cellular divalent inorganic cation homeostasis; GO:0090662 ATP hydrolysis coupled transmembrane transport; GO:0007420 brain development; GO:0023051 regulation of signaling; GO:0071384 cellular response to corticosteroid stimulus; GO:0003407 neural retina development; GO:0044699 single-organism process; GO:0071383 cellular response to steroid hormone stimulus; GO:0071305 cellular response to vitamin D; GO:0051234 establishment of localization; GO:0051385 response to mineralocorticoid; GO:1901660 calcium ion export; GO:0009605 response to external stimulus; GO:0007154 cell communication; GO:0055065 metal ion homeostasis; GO:0048545 response to steroid hormone; GO:0044057 regulation of system process; GO:0009719 response to endogenous stimulus; GO:0060322 head development; GO:0033273 response to vitamin; GO:0070887 cellular response to chemical stimulus; GO:0051412 response to corticosterone; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0014070 response to organic cyclic compound; GO:0098655 cation transmembrane transport; GO:0050801 ion homeostasis; GO:0055074 calcium ion homeostasis; GO:0044763 single-organism cellular process; GO:0098771 inorganic ion homeostasis; GO:0019725 cellular homeostasis; GO:0032501 multicellular organismal process; GO:0006874 cellular calcium ion homeostasis; GO:0051384 response to glucocorticoid; GO:0071396 cellular response to lipid; GO:1903779 regulation of cardiac conduction; GO:0006810 transport; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0032870 cellular response to hormone stimulus; GO:0007417 central nervous system development; GO:0007568 aging; GO:0072507 divalent inorganic cation homeostasis; GO:0048856 anatomical structure development; GO:0098662 inorganic cation transmembrane transport; GO:0044707 single-multicellular organism process; GO:0043010 camera-type eye development; GO:0034220 ion transmembrane transport; GO:0072511 divalent inorganic cation transport; GO:0009628 response to abiotic stimulus; GO:0030001 metal ion transport; GO:1903522 regulation of blood circulation; GO:0030003 cellular cation homeostasis; GO:0071310 cellular response to organic substance; GO:1901700 response to oxygen-containing compound; GO:0008016 regulation of heart contraction; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:0055082 cellular chemical homeostasis; GO:0031669 cellular response to nutrient levels; GO:0071295 cellular response to vitamin; GO:0042592 homeostatic process; GO:0009991 response to extracellular stimulus; GO:0033993 response to lipid; GO:0071386 cellular response to corticosterone stimulus; GO:0001654 eye development; GO:0055080 cation homeostasis; GO:0006816 calcium ion transport; GO:0006812 cation transport; GO:0033280 response to vitamin D; GO:0009266 response to temperature stimulus; GO:0031960 response to corticosteroid; GO:0099132 ATP hydrolysis coupled cation transmembrane transport; GO:0007275 multicellular organism development; GO:0099131 ATP hydrolysis coupled ion transmembrane transport; GO:0071389 cellular response to mineralocorticoid stimulus; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0070588 calcium ion transmembrane transport; GO:0060041 retina development in camera-type eye; GO:1901655 cellular response to ketone; GO:0006950 response to stress; GO:0071385 cellular response to glucocorticoid stimulus; GO:0098660 inorganic ion transmembrane transport; GO:0048731 system development; GO:0071496 cellular response to external stimulus; GO:0071407 cellular response to organic cyclic compound; GO:0010033 response to organic substance; GO:0007584 response to nutrient; GO:0031668 cellular response to extracellular stimulus; GO:0055085 transmembrane transport; GO:0009409 response to cold; GO:1901701 cellular response to oxygen-containing compound; GO:0006873 cellular ion homeostasis; GO:0071495 cellular response to endogenous stimulus; GO:0006811 ion transport; GO:0044767 single-organism developmental process; GO:0031670 cellular response to nutrient; GO:0006875 cellular metal ion homeostasis; GO:0031667 response to nutrient levels; GO:0009725 response to hormone; GO:0007423 sensory organ development; GO:0051179 localization; GO:0065007 biological regulation; GO:1901654 response to ketone; GO:0070838 divalent metal ion transport; ","GO:0016323 basolateral plasma membrane; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0016324 apical plasma membrane; GO:0098857 membrane microdomain; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0043025 neuronal cell body; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0009898 cytoplasmic side of plasma membrane; GO:0098562 cytoplasmic side of membrane; GO:0032809 neuronal cell body membrane; GO:0032589 neuron projection membrane; GO:0070062 extracellular exosome; GO:0098590 plasma membrane region; GO:0031256 leading edge membrane; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0098589 membrane region; GO:1903561 extracellular vesicle; GO:0097060 synaptic membrane; GO:0043005 neuron projection; GO:0045121 membrane raft; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0045177 apical part of cell; GO:0044456 synapse part; GO:0098552 side of membrane; GO:0031252 cell leading edge; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0031226 intrinsic component of plasma membrane; GO:0044463 cell projection part; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0045202 synapse; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0036477 somatodendritic compartment; GO:0044459 plasma membrane part; GO:0044298 cell body membrane; GO:0031253 cell projection membrane; GO:0044297 cell body; GO:0032590 dendrite membrane; GO:0043230 extracellular organelle; GO:0032591 dendritic spine membrane; ","GO:0042625 ATPase coupled ion transmembrane transporter activity; GO:1901265 nucleoside phosphate binding; GO:0015399 primary active transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0022891 substrate-specific transmembrane transporter activity; GO:0016887 ATPase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0046873 metal ion transmembrane transporter activity; GO:0016462 pyrophosphatase activity; GO:0019829 cation-transporting ATPase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0043492 ATPase activity, coupled to movement of substances; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0022890 inorganic cation transmembrane transporter activity; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005215 transporter activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0022804 active transmembrane transporter activity; GO:0005524 ATP binding; GO:0015075 ion transmembrane transporter activity; GO:0022853 active ion transmembrane transporter activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0005516 calmodulin binding; GO:0030165 PDZ domain binding; GO:0032549 ribonucleoside binding; GO:0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity; GO:0015662 ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism; GO:0072509 divalent inorganic cation transmembrane transporter activity; GO:0097367 carbohydrate derivative binding; GO:0005388 calcium-transporting ATPase activity; GO:0042626 ATPase activity, coupled to transmembrane movement of substances; GO:0042623 ATPase activity, coupled; GO:0046872 metal ion binding; GO:0015085 calcium ion transmembrane transporter activity; GO:0032555 purine ribonucleotide binding; GO:0019904 protein domain specific binding; GO:0001883 purine nucleoside binding; GO:0008324 cation transmembrane transporter activity; GO:0022857 transmembrane transporter activity; GO:0036094 small molecule binding; ","K05850","ATP2B; Ca2+ transporting ATPase, plasma membrane [EC:3.6.3.8]","hsa04925 Aldosterone synthesis and secretion - Homo sapiens (human); hsa04024 cAMP signaling pathway - Homo sapiens (human); hsa04978 Mineral absorption - Homo sapiens (human); hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human); hsa04972 Pancreatic secretion - Homo sapiens (human); hsa04970 Salivary secretion - Homo sapiens (human); hsa04961 Endocrine and other factor-regulated calcium reabsorption - Homo sapiens (human); hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human); hsa04020 Calcium signaling pathway - Homo sapiens (human); ","IPR023298; IPR004014; IPR022141; IPR023299; IPR008250; IPR023214; IPR006068; ","\"P-type ATPase,  transmembrane domain; Cation-transporting P-type ATPase, N-terminal; Plasma membrane calcium transporting P-type ATPase, C-terminal; P-type ATPase, cytoplasmic domain N; P-type ATPase, A  domain; HAD-like domain; Cation-transporting P-type ATPase, C-terminal; \"\r"]
["P20036","HLA class II histocompatibility antigen, DP alpha 1 chain OS=Homo sapiens OX=9606 GN=HLA-DPA1","HLA-DPA1",29.38,35.119,11.2,2,2,2,0.843,0.858,0.889,1.137,1.165,1.098,1.313,0.000302,"plasma membrane\r","GO:0044700 single organism signaling; GO:0050863 regulation of T cell activation; GO:0002694 regulation of leukocyte activation; GO:0032944 regulation of mononuclear cell proliferation; GO:0007166 cell surface receptor signaling pathway; GO:0071346 cellular response to interferon-gamma; GO:0044699 single-organism process; GO:0031294 lymphocyte costimulation; GO:0051249 regulation of lymphocyte activation; GO:0071345 cellular response to cytokine stimulus; GO:0060333 interferon-gamma-mediated signaling pathway; GO:0007165 signal transduction; GO:0050671 positive regulation of lymphocyte proliferation; GO:0007154 cell communication; GO:0032946 positive regulation of mononuclear cell proliferation; GO:0051240 positive regulation of multicellular organismal process; GO:0070663 regulation of leukocyte proliferation; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0070887 cellular response to chemical stimulus; GO:0050851 antigen receptor-mediated signaling pathway; GO:0051716 cellular response to stimulus; GO:0034097 response to cytokine; GO:0048002 antigen processing and presentation of peptide antigen; GO:0048522 positive regulation of cellular process; GO:0050670 regulation of lymphocyte proliferation; GO:0051251 positive regulation of lymphocyte activation; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0002495 antigen processing and presentation of peptide antigen via MHC class II; GO:0050776 regulation of immune response; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0042221 response to chemical; GO:0050865 regulation of cell activation; GO:0050789 regulation of biological process; GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; GO:0048583 regulation of response to stimulus; GO:0002682 regulation of immune system process; GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II; GO:0006952 defense response; GO:0050794 regulation of cellular process; GO:0042127 regulation of cell proliferation; GO:0042102 positive regulation of T cell proliferation; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0001819 positive regulation of cytokine production; GO:0071310 cellular response to organic substance; GO:0050896 response to stimulus; GO:0045087 innate immune response; GO:0051239 regulation of multicellular organismal process; GO:0032729 positive regulation of interferon-gamma production; GO:0050867 positive regulation of cell activation; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:0002757 immune response-activating signal transduction; GO:0050778 positive regulation of immune response; GO:0009987 cellular process; GO:0019221 cytokine-mediated signaling pathway; GO:0032649 regulation of interferon-gamma production; GO:0002253 activation of immune response; GO:0045785 positive regulation of cell adhesion; GO:0006950 response to stress; GO:0022409 positive regulation of cell-cell adhesion; GO:0031295 T cell costimulation; GO:0042129 regulation of T cell proliferation; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0034341 response to interferon-gamma; GO:1903039 positive regulation of leukocyte cell-cell adhesion; GO:0048518 positive regulation of biological process; GO:0022407 regulation of cell-cell adhesion; GO:0030155 regulation of cell adhesion; GO:0002696 positive regulation of leukocyte activation; GO:0019882 antigen processing and presentation; GO:0070665 positive regulation of leukocyte proliferation; GO:0050852 T cell receptor signaling pathway; GO:0050870 positive regulation of T cell activation; GO:0002684 positive regulation of immune system process; GO:0001817 regulation of cytokine production; GO:0048584 positive regulation of response to stimulus; GO:0006955 immune response; GO:0008284 positive regulation of cell proliferation; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0045334 clathrin-coated endocytic vesicle; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0032588 trans-Golgi network membrane; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0005765 lysosomal membrane; GO:0042613 MHC class II protein complex; GO:0030136 clathrin-coated vesicle; GO:0005622 intracellular; GO:0005764 lysosome; GO:0098791 Golgi subcompartment; GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0098552 side of membrane; GO:0000323 lytic vacuole; GO:0010008 endosome membrane; GO:0031226 intrinsic component of plasma membrane; GO:0030666 endocytic vesicle membrane; GO:0098797 plasma membrane protein complex; GO:0044440 endosomal part; GO:0012506 vesicle membrane; GO:0030135 coated vesicle; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0098553 lumenal side of endoplasmic reticulum membrane; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0030176 integral component of endoplasmic reticulum membrane; GO:0043234 protein complex; GO:0030133 transport vesicle; GO:0030658 transport vesicle membrane; GO:0005783 endoplasmic reticulum; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0042611 MHC protein complex; GO:0030669 clathrin-coated endocytic vesicle membrane; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0030662 coated vesicle membrane; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0031227 intrinsic component of endoplasmic reticulum membrane; GO:0044431 Golgi apparatus part; GO:0005768 endosome; GO:0030139 endocytic vesicle; GO:0012507 ER to Golgi transport vesicle membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0030134 ER to Golgi transport vesicle; GO:0012505 endomembrane system; GO:0030665 clathrin-coated vesicle membrane; GO:0016021 integral component of membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0044432 endoplasmic reticulum part; GO:0005802 trans-Golgi network; GO:0005774 vacuolar membrane; GO:0009986 cell surface; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; GO:0031984 organelle subcompartment; ","GO:0038023 signaling receptor activity; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0042277 peptide binding; GO:0005488 binding; GO:0005515 protein binding; GO:0042605 peptide antigen binding; GO:0033218 amide binding; GO:0004888 transmembrane signaling receptor activity; GO:0004871 signal transducer activity; GO:0032395 MHC class II receptor activity; GO:0003823 antigen binding; GO:0099600 transmembrane receptor activity; ","K06752","MHC2; major histocompatibility complex, class II","hsa05330 Allograft rejection - Homo sapiens (human); hsa05322 Systemic lupus erythematosus - Homo sapiens (human); hsa04672 Intestinal immune network for IgA production - Homo sapiens (human); hsa05152 Tuberculosis - Homo sapiens (human); hsa05150 Staphylococcus aureus infection - Homo sapiens (human); hsa05323 Rheumatoid arthritis - Homo sapiens (human); hsa05168 Herpes simplex infection - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); hsa05140 Leishmaniasis - Homo sapiens (human); hsa04640 Hematopoietic cell lineage - Homo sapiens (human); hsa05166 HTLV-I infection - Homo sapiens (human); hsa04940 Type I diabetes mellitus - Homo sapiens (human); hsa04514 Cell adhesion molecules (CAMs) - Homo sapiens (human); hsa04658 Th1 and Th2 cell differentiation - Homo sapiens (human); hsa05320 Autoimmune thyroid disease - Homo sapiens (human); hsa05164 Influenza A - Homo sapiens (human); hsa05145 Toxoplasmosis - Homo sapiens (human); hsa05310 Asthma - Homo sapiens (human); hsa04659 Th17 cell differentiation - Homo sapiens (human); hsa05321 Inflammatory bowel disease (IBD) - Homo sapiens (human); hsa05416 Viral myocarditis - Homo sapiens (human); hsa04612 Antigen processing and presentation - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); hsa05332 Graft-versus-host disease - Homo sapiens (human); ","IPR001003; IPR007110; IPR013783; IPR014745; IPR011162; IPR003597; IPR032431; ","\"MHC class II, alpha chain, N-terminal; Immunoglobulin-like domain; Immunoglobulin-like fold; MHC class II, alpha/beta chain, N-terminal; MHC classes I/II-like antigen recognition protein; Immunoglobulin C1-set; Immunoglobulin C1-set, C-terminal extension; \"\r"]
["P20042","Eukaryotic translation initiation factor 2 subunit 2 OS=Homo sapiens OX=9606 GN=EIF2S2","EIF2S2",38.388,48.774,32.4,9,14,9,0.829,0.861,0.855,1.118,1.129,1.184,1.348,1.44E-4,"nucleus\r","GO:0006518 peptide metabolic process; GO:0022414 reproductive process; GO:0043009 chordate embryonic development; GO:0008584 male gonad development; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0044702 single organism reproductive process; GO:0006413 translational initiation; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006412 translation; GO:0009790 embryo development; GO:0002176 male germ cell proliferation; GO:0032502 developmental process; GO:0003006 developmental process involved in reproduction; GO:0043043 peptide biosynthetic process; GO:0019953 sexual reproduction; GO:0048608 reproductive structure development; GO:0043603 cellular amide metabolic process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0048513 animal organ development; GO:0001701 in utero embryonic development; GO:0044260 cellular macromolecule metabolic process; GO:0036093 germ cell proliferation; GO:0048609 multicellular organismal reproductive process; GO:0048856 anatomical structure development; GO:0000003 reproduction; GO:0044707 single-multicellular organism process; GO:0046661 male sex differentiation; GO:0008406 gonad development; GO:0044267 cellular protein metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0007548 sex differentiation; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0061458 reproductive system development; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0045137 development of primary sexual characteristics; GO:0048731 system development; GO:0009792 embryo development ending in birth or egg hatching; GO:0006807 nitrogen compound metabolic process; GO:0008283 cell proliferation; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0007276 gamete generation; GO:0032504 multicellular organism reproduction; GO:0055085 transmembrane transport; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044767 single-organism developmental process; GO:0044703 multi-organism reproductive process; GO:0010467 gene expression; GO:0046546 development of primary male sexual characteristics; GO:0043604 amide biosynthetic process; GO:0051179 localization; GO:1901564 organonitrogen compound metabolic process; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005850 eukaryotic translation initiation factor 2 complex; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0043234 protein complex; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0008135 translation factor activity, RNA binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0043167 ion binding; GO:0003676 nucleic acid binding; GO:0003743 translation initiation factor activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; ","K03238","EIF2S2; translation initiation factor 2 subunit 2","hsa03013 RNA transport - Homo sapiens (human); ","IPR016189; IPR016190; IPR002735; ","\"Translation initiation factor IF2/IF5, N-terminal; Translation initiation factor IF2/IF5, zinc-binding; Translation initiation factor IF2/IF5; \"\r"]
["P20073","Annexin A7 OS=Homo sapiens OX=9606 GN=ANXA7","ANXA7",52.739,179.62,37.1,18,35,18,1.072,1.016,1.047,0.929,0.943,0.966,0.905,0.00668,"cyto_nucl\r","GO:0065008 regulation of biological quality; GO:0072503 cellular divalent inorganic cation homeostasis; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0006914 autophagy; GO:0044237 cellular metabolic process; GO:0007610 behavior; GO:0008152 metabolic process; GO:0008360 regulation of cell shape; GO:0032535 regulation of cellular component size; GO:0055065 metal ion homeostasis; GO:0010035 response to inorganic substance; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0014070 response to organic cyclic compound; GO:0010468 regulation of gene expression; GO:0009888 tissue development; GO:0006970 response to osmotic stress; GO:0050801 ion homeostasis; GO:0055074 calcium ion homeostasis; GO:0044763 single-organism cellular process; GO:0098771 inorganic ion homeostasis; GO:0019725 cellular homeostasis; GO:0061025 membrane fusion; GO:0009651 response to salt stress; GO:0010605 negative regulation of macromolecule metabolic process; GO:0010038 response to metal ion; GO:0051704 multi-organism process; GO:0006874 cellular calcium ion homeostasis; GO:0051705 multi-organism behavior; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0030104 water homeostasis; GO:0019222 regulation of metabolic process; GO:0048856 anatomical structure development; GO:0072507 divalent inorganic cation homeostasis; GO:0030855 epithelial cell differentiation; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0060255 regulation of macromolecule metabolic process; GO:0009628 response to abiotic stimulus; GO:0030003 cellular cation homeostasis; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0007599 hemostasis; GO:0055082 cellular chemical homeostasis; GO:0042592 homeostatic process; GO:0006884 cell volume homeostasis; GO:0030154 cell differentiation; GO:0035176 social behavior; GO:0008361 regulation of cell size; GO:0009992 cellular water homeostasis; GO:0055080 cation homeostasis; GO:0051592 response to calcium ion; GO:0044248 cellular catabolic process; GO:0051703 intraspecies interaction between organisms; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0050878 regulation of body fluid levels; GO:0006950 response to stress; GO:0010629 negative regulation of gene expression; GO:0008283 cell proliferation; GO:0010033 response to organic substance; GO:0009892 negative regulation of metabolic process; GO:0006873 cellular ion homeostasis; GO:0044767 single-organism developmental process; GO:0061024 membrane organization; GO:0022603 regulation of anatomical structure morphogenesis; GO:0090066 regulation of anatomical structure size; GO:0006875 cellular metal ion homeostasis; GO:0051128 regulation of cellular component organization; GO:0022604 regulation of cell morphogenesis; GO:0009056 catabolic process; GO:0050793 regulation of developmental process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043229 intracellular organelle; GO:0005635 nuclear envelope; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044432 endoplasmic reticulum part; GO:0031975 envelope; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0003723 RNA binding; GO:0005544 calcium-dependent phospholipid binding; GO:0005102 receptor binding; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0005178 integrin binding; GO:0005515 protein binding; GO:0048306 calcium-dependent protein binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0050839 cell adhesion molecule binding; GO:0005488 binding; GO:0005543 phospholipid binding; GO:0003676 nucleic acid binding; GO:0008289 lipid binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0043168 anion binding; GO:0005509 calcium ion binding; GO:0032403 protein complex binding; ","K17095"]
["P20336","Ras-related protein Rab-3A OS=Homo sapiens OX=9606 GN=RAB3A","RAB3A",24.984,21.916,10.5,2,3,1,0.858,0.881,0.852,1.042,1.159,1.196,1.311,3.3E-3,"cytoskeleton\r","GO:0044700 single organism signaling; GO:0060627 regulation of vesicle-mediated transport; GO:0021700 developmental maturation; GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0030323 respiratory tube development; GO:0032989 cellular component morphogenesis; GO:0007269 neurotransmitter secretion; GO:0031338 regulation of vesicle fusion; GO:0050877 neurological system process; GO:0015031 protein transport; GO:0099003 vesicle-mediated transport in synapse; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0008104 protein localization; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0048489 synaptic vesicle transport; GO:0048790 maintenance of presynaptic active zone structure; GO:0045054 constitutive secretory pathway; GO:0045921 positive regulation of exocytosis; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0048812 neuron projection morphogenesis; GO:0007264 small GTPase mediated signal transduction; GO:0048168 regulation of neuronal synaptic plasticity; GO:0046942 carboxylic acid transport; GO:0016188 synaptic vesicle maturation; GO:0032501 multicellular organismal process; GO:1902803 regulation of synaptic vesicle transport; GO:0000902 cell morphogenesis; GO:0006810 transport; GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane; GO:0048513 animal organ development; GO:0051336 regulation of hydrolase activity; GO:0007267 cell-cell signaling; GO:0050790 regulation of catalytic activity; GO:0032781 positive regulation of ATPase activity; GO:0099643 signal release from synapse; GO:0014047 glutamate secretion; GO:0051047 positive regulation of secretion; GO:0051640 organelle localization; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0044707 single-multicellular organism process; GO:0043954 cellular component maintenance; GO:0002283 neutrophil activation involved in immune response; GO:0009628 response to abiotic stimulus; GO:0017157 regulation of exocytosis; GO:0009791 post-embryonic development; GO:0060341 regulation of cellular localization; GO:0009653 anatomical structure morphogenesis; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0051345 positive regulation of hydrolase activity; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0060541 respiratory system development; GO:0007409 axonogenesis; GO:0006865 amino acid transport; GO:1902580 single-organism cellular localization; GO:0007275 multicellular organism development; GO:0051588 regulation of neurotransmitter transport; GO:0048167 regulation of synaptic plasticity; GO:0036465 synaptic vesicle recycling; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0050804 modulation of synaptic transmission; GO:0016079 synaptic vesicle exocytosis; GO:0050975 sensory perception of touch; GO:0051602 response to electrical stimulus; GO:0002376 immune system process; GO:0023061 signal release; GO:0071702 organic substance transport; GO:0051656 establishment of organelle localization; GO:0015849 organic acid transport; GO:0002263 cell activation involved in immune response; GO:0050808 synapse organization; GO:0097480 establishment of synaptic vesicle localization; GO:0045184 establishment of protein localization; GO:0030182 neuron differentiation; GO:0045055 regulated exocytosis; GO:0099536 synaptic signaling; GO:0006811 ion transport; GO:0097479 synaptic vesicle localization; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0006835 dicarboxylic acid transport; GO:0001775 cell activation; GO:0006955 immune response; GO:0051179 localization; GO:0007268 chemical synaptic transmission; GO:0006887 exocytosis; GO:0046717 acid secretion; GO:0001505 regulation of neurotransmitter levels; GO:0023051 regulation of signaling; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0051046 regulation of secretion; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0048172 regulation of short-term neuronal synaptic plasticity; GO:0099504 synaptic vesicle cycle; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:1903307 positive regulation of regulated secretory pathway; GO:0032990 cell part morphogenesis; GO:0007005 mitochondrion organization; GO:0048858 cell projection morphogenesis; GO:0098916 anterograde trans-synaptic signaling; GO:0033036 macromolecule localization; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:0030324 lung development; GO:0051650 establishment of vesicle localization; GO:0035295 tube development; GO:0007600 sensory perception; GO:0002446 neutrophil mediated immunity; GO:0003016 respiratory system process; GO:0007274 neuromuscular synaptic transmission; GO:0048522 positive regulation of cellular process; GO:0032386 regulation of intracellular transport; GO:0023052 signaling; GO:1903530 regulation of secretion by cell; GO:0046928 regulation of neurotransmitter secretion; GO:0002444 myeloid leukocyte mediated immunity; GO:1902582 single-organism intracellular transport; GO:0051050 positive regulation of transport; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0043462 regulation of ATPase activity; GO:1903532 positive regulation of secretion by cell; GO:0030030 cell projection organization; GO:0032940 secretion by cell; GO:0065009 regulation of molecular function; GO:0043299 leukocyte degranulation; GO:0048856 anatomical structure development; GO:0050954 sensory perception of mechanical stimulus; GO:0016043 cellular component organization; GO:0002252 immune effector process; GO:0099531 presynaptic process involved in chemical synaptic transmission; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0061670 evoked neurotransmitter secretion; GO:0000904 cell morphogenesis involved in differentiation; GO:2000300 regulation of synaptic vesicle exocytosis; GO:1990709 presynaptic active zone organization; GO:0030154 cell differentiation; GO:0051648 vesicle localization; GO:0099537 trans-synaptic signaling; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0003008 system process; GO:0035556 intracellular signal transduction; GO:0051049 regulation of transport; GO:0017156 calcium ion regulated exocytosis; GO:0033043 regulation of organelle organization; GO:0016050 vesicle organization; GO:0099558 maintenance of synapse structure; GO:0043312 neutrophil degranulation; GO:1903305 regulation of regulated secretory pathway; GO:0031175 neuron projection development; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0051641 cellular localization; GO:0006820 anion transport; GO:0002366 leukocyte activation involved in immune response; GO:0061564 axon development; GO:0007585 respiratory gaseous exchange; GO:0015711 organic anion transport; GO:0042119 neutrophil activation; GO:0044767 single-organism developmental process; GO:0051128 regulation of cellular component organization; GO:0017158 regulation of calcium ion-dependent exocytosis; GO:0071705 nitrogen compound transport; GO:0006836 neurotransmitter transport; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0070081 clathrin-sculpted monoamine transport vesicle; GO:0005623 cell; GO:0044422 organelle part; GO:0070382 exocytic vesicle; GO:0030136 clathrin-coated vesicle; GO:0008021 synaptic vesicle; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0043005 neuron projection; GO:0061202 clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane; GO:0044306 neuron projection terminus; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0042995 cell projection; GO:0012506 vesicle membrane; GO:0030672 synaptic vesicle membrane; GO:0030135 coated vesicle; GO:0005576 extracellular region; GO:0033267 axon part; GO:0005886 plasma membrane; GO:0030424 axon; GO:0030667 secretory granule membrane; GO:0061200 clathrin-sculpted gamma-aminobutyric acid transport vesicle; GO:0060198 clathrin-sculpted vesicle; GO:0043195 terminal bouton; GO:0070083 clathrin-sculpted monoamine transport vesicle membrane; GO:0043234 protein complex; GO:0097223 sperm part; GO:0030133 transport vesicle; GO:0043230 extracellular organelle; GO:0031300 intrinsic component of organelle membrane; GO:0030658 transport vesicle membrane; GO:0031410 cytoplasmic vesicle; GO:0060199 clathrin-sculpted glutamate transport vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0099501 exocytic vesicle membrane; GO:0098563 intrinsic component of synaptic vesicle membrane; GO:0043679 axon terminus; GO:0030662 coated vesicle membrane; GO:0044464 cell part; GO:0098793 presynapse; GO:0044425 membrane part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0030141 secretory granule; GO:0060203 clathrin-sculpted glutamate transport vesicle membrane; GO:0044456 synapse part; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0060200 clathrin-sculpted acetylcholine transport vesicle; GO:0044446 intracellular organelle part; GO:0031225 anchored component of membrane; GO:0012505 endomembrane system; GO:0098993 anchored component of synaptic vesicle membrane; GO:0044463 cell projection part; GO:0005829 cytosol; GO:0030665 clathrin-coated vesicle membrane; GO:0045202 synapse; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0001669 acrosomal vesicle; GO:0060201 clathrin-sculpted acetylcholine transport vesicle membrane; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0031489 myosin V binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0008092 cytoskeletal protein binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0003924 GTPase activity; GO:0043168 anion binding; GO:0008022 protein C-terminus binding; GO:0019001 guanyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005525 GTP binding; GO:0008047 enzyme activator activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0030742 GTP-dependent protein binding; GO:0051117 ATPase binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0001671 ATPase activator activity; GO:0097367 carbohydrate derivative binding; GO:0030234 enzyme regulator activity; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0032561 guanyl ribonucleotide binding; GO:0060590 ATPase regulator activity; GO:0017022 myosin binding; GO:0019899 enzyme binding; GO:0036094 small molecule binding; ","K07882","RAB3A; Ras-related protein Rab-3A","hsa04911 Insulin secretion - Homo sapiens (human); hsa04721 Synaptic vesicle cycle - Homo sapiens (human); ","IPR005225; IPR027417; ","Small GTP-binding protein domain; P-loop containing nucleoside triphosphate hydrolase; \r"]
["P20339","Ras-related protein Rab-5A OS=Homo sapiens OX=9606 GN=RAB5A","RAB5A",23.658,21.322,28.8,5,12,3,0.965,0.938,1.1,0.992,1.039,0.919,0.982,0.798,"mitochondria\r","GO:0044700 single organism signaling; GO:0060627 regulation of vesicle-mediated transport; GO:0019079 viral genome replication; GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0007166 cell surface receptor signaling pathway; GO:0060491 regulation of cell projection assembly; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0098927 vesicle-mediated transport between endosomal compartments; GO:0008610 lipid biosynthetic process; GO:0099003 vesicle-mediated transport in synapse; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0032879 regulation of localization; GO:0032535 regulation of cellular component size; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0016055 Wnt signaling pathway; GO:0008104 protein localization; GO:0044765 single-organism transport; GO:0051716 cellular response to stimulus; GO:0044088 regulation of vacuole organization; GO:0048489 synaptic vesicle transport; GO:0045921 positive regulation of exocytosis; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0007264 small GTPase mediated signal transduction; GO:0031323 regulation of cellular metabolic process; GO:0010506 regulation of autophagy; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0016241 regulation of macroautophagy; GO:1902803 regulation of synaptic vesicle transport; GO:0006810 transport; GO:0090407 organophosphate biosynthetic process; GO:2000785 regulation of autophagosome assembly; GO:0007267 cell-cell signaling; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0039694 viral RNA genome replication; GO:0050817 coagulation; GO:0051047 positive regulation of secretion; GO:0051640 organelle localization; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0044707 single-multicellular organism process; GO:0006661 phosphatidylinositol biosynthetic process; GO:0017157 regulation of exocytosis; GO:0060341 regulation of cellular localization; GO:0046483 heterocycle metabolic process; GO:1902578 single-organism localization; GO:0006139 nucleobase-containing compound metabolic process; GO:1902580 single-organism cellular localization; GO:0006898 receptor-mediated endocytosis; GO:0051588 regulation of neurotransmitter transport; GO:0036465 synaptic vesicle recycling; GO:0030100 regulation of endocytosis; GO:0044711 single-organism biosynthetic process; GO:0006950 response to stress; GO:0016192 vesicle-mediated transport; GO:0050804 modulation of synaptic transmission; GO:0071702 organic substance transport; GO:0051656 establishment of organelle localization; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0097480 establishment of synaptic vesicle localization; GO:0045184 establishment of protein localization; GO:0006793 phosphorus metabolic process; GO:0097479 synaptic vesicle localization; GO:0061024 membrane organization; GO:0019637 organophosphate metabolic process; GO:0006644 phospholipid metabolic process; GO:0051179 localization; GO:0001505 regulation of neurotransmitter levels; GO:0046486 glycerolipid metabolic process; GO:0031623 receptor internalization; GO:0023051 regulation of signaling; GO:0008654 phospholipid biosynthetic process; GO:0044699 single-organism process; GO:0051046 regulation of secretion; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:1902115 regulation of organelle assembly; GO:0006796 phosphate-containing compound metabolic process; GO:0099504 synaptic vesicle cycle; GO:0051234 establishment of localization; GO:0006909 phagocytosis; GO:0009611 response to wounding; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0006650 glycerophospholipid metabolic process; GO:0060070 canonical Wnt signaling pathway; GO:0039703 RNA replication; GO:0046488 phosphatidylinositol metabolic process; GO:0033036 macromolecule localization; GO:0006629 lipid metabolic process; GO:0051650 establishment of vesicle localization; GO:0043112 receptor metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0032386 regulation of intracellular transport; GO:1903530 regulation of secretion by cell; GO:0023052 signaling; GO:0046928 regulation of neurotransmitter secretion; GO:1902582 single-organism intracellular transport; GO:0051050 positive regulation of transport; GO:0198738 cell-cell signaling by wnt; GO:0016070 RNA metabolic process; GO:0016197 endosomal transport; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:1903532 positive regulation of secretion by cell; GO:0051036 regulation of endosome size; GO:0046474 glycerophospholipid biosynthetic process; GO:0019222 regulation of metabolic process; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0019058 viral life cycle; GO:0044087 regulation of cellular component biogenesis; GO:0031344 regulation of cell projection organization; GO:0050896 response to stimulus; GO:0007599 hemostasis; GO:0051489 regulation of filopodium assembly; GO:0071704 organic substance metabolic process; GO:2000300 regulation of synaptic vesicle exocytosis; GO:0016032 viral process; GO:0051648 vesicle localization; GO:0034641 cellular nitrogen compound metabolic process; GO:0016482 cytosolic transport; GO:0009987 cellular process; GO:0045022 early endosome to late endosome transport; GO:0050878 regulation of body fluid levels; GO:0035556 intracellular signal transduction; GO:0051049 regulation of transport; GO:2000286 receptor internalization involved in canonical Wnt signaling pathway; GO:0006807 nitrogen compound metabolic process; GO:0033043 regulation of organelle organization; GO:0006897 endocytosis; GO:1903305 regulation of regulated secretory pathway; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0045017 glycerolipid biosynthetic process; GO:0051641 cellular localization; GO:0042060 wound healing; GO:0090066 regulation of anatomical structure size; GO:0051128 regulation of cellular component organization; GO:0017158 regulation of calcium ion-dependent exocytosis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0030425 dendrite; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0098857 membrane microdomain; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0043025 neuronal cell body; GO:0098559 cytoplasmic side of early endosome membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0043228 non-membrane-bounded organelle; GO:0070382 exocytic vesicle; GO:0070062 extracellular exosome; GO:0030136 clathrin-coated vesicle; GO:0008021 synaptic vesicle; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0010009 cytoplasmic side of endosome membrane; GO:0098589 membrane region; GO:0043005 neuron projection; GO:0044306 neuron projection terminus; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0098552 side of membrane; GO:0031252 cell leading edge; GO:0010008 endosome membrane; GO:0042995 cell projection; GO:0030666 endocytic vesicle membrane; GO:0012506 vesicle membrane; GO:0044440 endosomal part; GO:0030135 coated vesicle; GO:0005576 extracellular region; GO:0033267 axon part; GO:0005886 plasma membrane; GO:0030424 axon; GO:0043195 terminal bouton; GO:0030133 transport vesicle; GO:0043230 extracellular organelle; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0098562 cytoplasmic side of membrane; GO:0030662 coated vesicle membrane; GO:0043679 axon terminus; GO:0048770 pigment granule; GO:0005856 cytoskeleton; GO:0044464 cell part; GO:0044425 membrane part; GO:0098793 presynapse; GO:0098805 whole membrane; GO:0030670 phagocytic vesicle membrane; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0031901 early endosome membrane; GO:0030139 endocytic vesicle; GO:0045121 membrane raft; GO:0044456 synapse part; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0042470 melanosome; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0045335 phagocytic vesicle; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0030665 clathrin-coated vesicle membrane; GO:0015629 actin cytoskeleton; GO:0045202 synapse; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0001726 ruffle; GO:0044297 cell body; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016462 pyrophosphatase activity; GO:0019003 GDP binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0003924 GTPase activity; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; ","K07887","RAB5A; Ras-related protein Rab-5A","hsa05152 Tuberculosis - Homo sapiens (human); hsa04144 Endocytosis - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); hsa04962 Vasopressin-regulated water reabsorption - Homo sapiens (human); hsa04014 Ras signaling pathway - Homo sapiens (human); hsa05014 Amyotrophic lateral sclerosis (ALS) - Homo sapiens (human); hsa05146 Amoebiasis - Homo sapiens (human); ","IPR005225; IPR027417; ","Small GTP-binding protein domain; P-loop containing nucleoside triphosphate hydrolase; \r"]
["P20340","Ras-related protein Rab-6A OS=Homo sapiens OX=9606 GN=RAB6A","RAB6A",23.593,42.099,36.5,8,21,4,1.012,0.923,0.983,1.037,1.051,1.041,1.072,0.124,"cytoplasm\r","GO:0044700 single organism signaling; GO:0072594 establishment of protein localization to organelle; GO:0045321 leukocyte activation; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0032259 methylation; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0010970 transport along microtubule; GO:0008213 protein alkylation; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0033365 protein localization to organelle; GO:0044419 interspecies interaction between organisms; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0006891 intra-Golgi vesicle-mediated transport; GO:0000301 retrograde transport, vesicle recycling within Golgi; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0007264 small GTPase mediated signal transduction; GO:0023052 signaling; GO:1902582 single-organism intracellular transport; GO:0051704 multi-organism process; GO:0002444 myeloid leukocyte mediated immunity; GO:0016197 endosomal transport; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0042147 retrograde transport, endosome to Golgi; GO:0018198 peptidyl-cysteine modification; GO:0032940 secretion by cell; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0043299 leukocyte degranulation; GO:0036211 protein modification process; GO:0072384 organelle transport along microtubule; GO:0051640 organelle localization; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0044267 cellular protein metabolic process; GO:0048193 Golgi vesicle transport; GO:0050896 response to stimulus; GO:0030705 cytoskeleton-dependent intracellular transport; GO:0099111 microtubule-based transport; GO:0071704 organic substance metabolic process; GO:0006479 protein methylation; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0016032 viral process; GO:0006886 intracellular protein transport; GO:1902580 single-organism cellular localization; GO:0036230 granulocyte activation; GO:0034613 cellular protein localization; GO:0016482 cytosolic transport; GO:0009987 cellular process; GO:0072385 minus-end-directed organelle transport along microtubule; GO:0034067 protein localization to Golgi apparatus; GO:0035556 intracellular signal transduction; GO:0072600 establishment of protein localization to Golgi; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0071702 organic substance transport; GO:0051656 establishment of organelle localization; GO:0044238 primary metabolic process; GO:0043312 neutrophil degranulation; GO:0007017 microtubule-based process; GO:0002263 cell activation involved in immune response; GO:0051641 cellular localization; GO:0018193 peptidyl-amino acid modification; GO:0002366 leukocyte activation involved in immune response; GO:0045184 establishment of protein localization; GO:0007018 microtubule-based movement; GO:0019882 antigen processing and presentation; GO:0070727 cellular macromolecule localization; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0034498 early endosome to Golgi transport; GO:0006890 retrograde vesicle-mediated transport, Golgi to ER; GO:0043414 macromolecule methylation; GO:0061024 membrane organization; GO:0018125 peptidyl-cysteine methylation; GO:0006928 movement of cell or subcellular component; GO:0001775 cell activation; GO:0000042 protein targeting to Golgi; GO:0043412 macromolecule modification; GO:0051179 localization; GO:0006955 immune response; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:0006887 exocytosis; ","GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032588 trans-Golgi network membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0070382 exocytic vesicle; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0098805 whole membrane; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0098791 Golgi subcompartment; GO:0044431 Golgi apparatus part; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0070381 endosome to plasma membrane transport vesicle; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0030667 secretory granule membrane; GO:0044432 endoplasmic reticulum part; GO:0005802 trans-Golgi network; GO:0030133 transport vesicle; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0031984 organelle subcompartment; ","GO:1901265 nucleoside phosphate binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0031489 myosin V binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0008092 cytoskeletal protein binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0003924 GTPase activity; GO:0043168 anion binding; GO:0019001 guanyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0019904 protein domain specific binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0032561 guanyl ribonucleotide binding; GO:0017022 myosin binding; GO:0036094 small molecule binding; ","K07893",null,null,"IPR005225; IPR027417; ","Small GTP-binding protein domain; P-loop containing nucleoside triphosphate hydrolase; \r"]
["P20591","Interferon-induced GTP-binding protein Mx1 OS=Homo sapiens OX=9606 GN=MX1","MX1",75.519,75.71,26.6,15,20,13,0.6,0.578,0.611,1.447,1.432,1.356,2.367,2.45e-06,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0007166 cell surface receptor signaling pathway; GO:0098542 defense response to other organism; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0071345 cellular response to cytokine stimulus; GO:0009607 response to biotic stimulus; GO:0009605 response to external stimulus; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0006915 apoptotic process; GO:0007005 mitochondrion organization; GO:0044419 interspecies interaction between organisms; GO:0070887 cellular response to chemical stimulus; GO:0048525 negative regulation of viral process; GO:0051716 cellular response to stimulus; GO:0071822 protein complex subunit organization; GO:0034097 response to cytokine; GO:0044763 single-organism cellular process; GO:0034340 response to type I interferon; GO:0061025 membrane fusion; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0045069 regulation of viral genome replication; GO:0023052 signaling; GO:0051704 multi-organism process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0051607 defense response to virus; GO:0051258 protein polymerization; GO:0006952 defense response; GO:0070271 protein complex biogenesis; GO:0009615 response to virus; GO:0050794 regulation of cellular process; GO:0060337 type I interferon signaling pathway; GO:0016043 cellular component organization; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0002252 immune effector process; GO:0071310 cellular response to organic substance; GO:0048285 organelle fission; GO:0090148 membrane fission; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0045087 innate immune response; GO:1903901 negative regulation of viral life cycle; GO:0003373 dynamin family protein polymerization involved in membrane fission; GO:0016032 viral process; GO:0003374 dynamin family protein polymerization involved in mitochondrial fission; GO:0071357 cellular response to type I interferon; GO:0019221 cytokine-mediated signaling pathway; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0043623 cellular protein complex assembly; GO:0034622 cellular macromolecular complex assembly; GO:0006950 response to stress; GO:0043900 regulation of multi-organism process; GO:0050792 regulation of viral process; GO:0044802 single-organism membrane organization; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0045071 negative regulation of viral genome replication; GO:0043933 macromolecular complex subunit organization; GO:0043901 negative regulation of multi-organism process; GO:0000266 mitochondrial fission; GO:0008219 cell death; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0012501 programmed cell death; GO:0006955 immune response; GO:1903900 regulation of viral life cycle; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0031965 nuclear membrane; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0048471 perinuclear region of cytoplasm; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0005635 nuclear envelope; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044432 endoplasmic reticulum part; GO:0031975 envelope; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0042802 identical protein binding; GO:0008092 cytoskeletal protein binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0008017 microtubule binding; GO:0032550 purine ribonucleoside binding; GO:0003924 GTPase activity; GO:0043168 anion binding; GO:0019001 guanyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0015631 tubulin binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0032561 guanyl ribonucleotide binding; GO:0036094 small molecule binding; ","K14754","MX1; interferon-induced GTP-binding protein Mx1","hsa05162 Measles - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa05164 Influenza A - Homo sapiens (human); ","IPR030381; IPR003130; IPR020850; IPR001401; IPR027417; IPR000375; ","\"Dynamin-type guanine nucleotide-binding (G) domain; Dynamin GTPase effector; GTPase effector domain; Dynamin, GTPase domain; P-loop containing nucleoside triphosphate hydrolase; Dynamin central domain; \"\r"]
["P20592","Interferon-induced GTP-binding protein Mx2 OS=Homo sapiens OX=9606 GN=MX2","MX2",82.088,3.0492,7,5,7,3,0.966,0.964,0.932,1.082,1.01,1.05,1.098,0.0157,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0050658 RNA transport; GO:0044700 single organism signaling; GO:0007166 cell surface receptor signaling pathway; GO:0098542 defense response to other organism; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0071345 cellular response to cytokine stimulus; GO:0015031 protein transport; GO:0009607 response to biotic stimulus; GO:0051234 establishment of localization; GO:0009605 response to external stimulus; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0050657 nucleic acid transport; GO:0065003 macromolecular complex assembly; GO:0032879 regulation of localization; GO:0015931 nucleobase-containing compound transport; GO:0007005 mitochondrion organization; GO:0044419 interspecies interaction between organisms; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0051726 regulation of cell cycle; GO:0070887 cellular response to chemical stimulus; GO:0051716 cellular response to stimulus; GO:0071822 protein complex subunit organization; GO:0034097 response to cytokine; GO:0044763 single-organism cellular process; GO:0061025 membrane fusion; GO:0034340 response to type I interferon; GO:0032386 regulation of intracellular transport; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0023052 signaling; GO:0051704 multi-organism process; GO:0006810 transport; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0051607 defense response to virus; GO:0051258 protein polymerization; GO:0006952 defense response; GO:0070271 protein complex biogenesis; GO:0009615 response to virus; GO:0050794 regulation of cellular process; GO:0060337 type I interferon signaling pathway; GO:0016043 cellular component organization; GO:0002252 immune effector process; GO:0071310 cellular response to organic substance; GO:0051028 mRNA transport; GO:0048285 organelle fission; GO:0090148 membrane fission; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0045087 innate immune response; GO:0051236 establishment of RNA localization; GO:0060341 regulation of cellular localization; GO:0003373 dynamin family protein polymerization involved in membrane fission; GO:0016032 viral process; GO:0003374 dynamin family protein polymerization involved in mitochondrial fission; GO:0071357 cellular response to type I interferon; GO:0019221 cytokine-mediated signaling pathway; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0043623 cellular protein complex assembly; GO:0034622 cellular macromolecular complex assembly; GO:0006950 response to stress; GO:0051049 regulation of transport; GO:0006403 RNA localization; GO:0044802 single-organism membrane organization; GO:0002376 immune system process; GO:0071702 organic substance transport; GO:0010033 response to organic substance; GO:0043933 macromolecular complex subunit organization; GO:0000266 mitochondrial fission; GO:0045184 establishment of protein localization; GO:0046822 regulation of nucleocytoplasmic transport; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0035455 response to interferon-alpha; GO:0006955 immune response; GO:0051179 localization; GO:0071705 nitrogen compound transport; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0043229 intracellular organelle; GO:0005643 nuclear pore; GO:0044429 mitochondrial part; GO:0031090 organelle membrane; GO:0005635 nuclear envelope; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0012505 endomembrane system; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0031975 envelope; GO:0043227 membrane-bounded organelle; GO:0043234 protein complex; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0008092 cytoskeletal protein binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0008017 microtubule binding; GO:0032550 purine ribonucleoside binding; GO:0003924 GTPase activity; GO:0043168 anion binding; GO:0019001 guanyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0015631 tubulin binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0032561 guanyl ribonucleotide binding; GO:0036094 small molecule binding; ",{"$nulls":3},"IPR030381; IPR003130; IPR020850; IPR001401; IPR027417; IPR000375; ","\"Dynamin-type guanine nucleotide-binding (G) domain; Dynamin GTPase effector; GTPase effector domain; Dynamin, GTPase domain; P-loop containing nucleoside triphosphate hydrolase; Dynamin central domain; \"\r"]
["P20618","Proteasome subunit beta type-1 OS=Homo sapiens OX=9606 GN=PSMB1","PSMB1",26.489,54.427,31.5,6,9,6,0.984,0.999,1.029,1.043,0.999,0.961,0.997,0.907,"cytoplasm\r","GO:0044700 single organism signaling; GO:0010608 posttranscriptional regulation of gene expression; GO:0051443 positive regulation of ubiquitin-protein transferase activity; GO:0031347 regulation of defense response; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:1903364 positive regulation of cellular protein catabolic process; GO:0008152 metabolic process; GO:0044093 positive regulation of molecular function; GO:0090263 positive regulation of canonical Wnt signaling pathway; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0016055 Wnt signaling pathway; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0006521 regulation of cellular amino acid metabolic process; GO:0080090 regulation of primary metabolic process; GO:0010972 negative regulation of G2/M transition of mitotic cell cycle; GO:0044763 single-organism cellular process; GO:0060828 regulation of canonical Wnt signaling pathway; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0043086 negative regulation of catalytic activity; GO:0033209 tumor necrosis factor-mediated signaling pathway; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0000165 MAPK cascade; GO:0019884 antigen processing and presentation of exogenous antigen; GO:1901575 organic substance catabolic process; GO:0007267 cell-cell signaling; GO:0002223 stimulatory C-type lectin receptor signaling pathway; GO:0030163 protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0060071 Wnt signaling pathway, planar cell polarity pathway; GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0016310 phosphorylation; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0043487 regulation of RNA stability; GO:0000209 protein polyubiquitination; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0009889 regulation of biosynthetic process; GO:0009896 positive regulation of catabolic process; GO:0043620 regulation of DNA-templated transcription in response to stress; GO:0070482 response to oxygen levels; GO:0044248 cellular catabolic process; GO:0042176 regulation of protein catabolic process; GO:0038093 Fc receptor signaling pathway; GO:0050778 positive regulation of immune response; GO:0023014 signal transduction by protein phosphorylation; GO:0006950 response to stress; GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; GO:0016567 protein ubiquitination; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0002263 cell activation involved in immune response; GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress; GO:1903321 negative regulation of protein modification by small protein conjugation or removal; GO:0045055 regulated exocytosis; GO:0031398 positive regulation of protein ubiquitination; GO:0032446 protein modification by small protein conjugation; GO:0031325 positive regulation of cellular metabolic process; GO:0030177 positive regulation of Wnt signaling pathway; GO:1904668 positive regulation of ubiquitin protein ligase activity; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0006955 immune response; GO:0043412 macromolecule modification; GO:0070646 protein modification by small protein removal; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0031331 positive regulation of cellular catabolic process; GO:0044699 single-organism process; GO:0031400 negative regulation of protein modification process; GO:0006796 phosphate-containing compound metabolic process; GO:0031396 regulation of protein ubiquitination; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0045930 negative regulation of mitotic cell cycle; GO:0009893 positive regulation of metabolic process; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0034612 response to tumor necrosis factor; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0051726 regulation of cell cycle; GO:0034097 response to cytokine; GO:0031326 regulation of cellular biosynthetic process; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0198738 cell-cell signaling by wnt; GO:0010565 regulation of cellular ketone metabolic process; GO:0032940 secretion by cell; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0036211 protein modification process; GO:0090175 regulation of establishment of planar polarity; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0045786 negative regulation of cell cycle; GO:0044257 cellular protein catabolic process; GO:1901988 negative regulation of cell cycle phase transition; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0010498 proteasomal protein catabolic process; GO:0071704 organic substance metabolic process; GO:0045862 positive regulation of proteolysis; GO:2000027 regulation of organ morphogenesis; GO:0006468 protein phosphorylation; GO:0023056 positive regulation of signaling; GO:0016032 viral process; GO:0001666 response to hypoxia; GO:0002757 immune response-activating signal transduction; GO:0010647 positive regulation of cell communication; GO:0071453 cellular response to oxygen levels; GO:0019221 cytokine-mediated signaling pathway; GO:0031397 negative regulation of protein ubiquitination; GO:0006355 regulation of transcription, DNA-templated; GO:0035556 intracellular signal transduction; GO:0019941 modification-dependent protein catabolic process; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia; GO:1902749 regulation of cell cycle G2/M phase transition; GO:0043488 regulation of mRNA stability; GO:0043085 positive regulation of catalytic activity; GO:0002366 leukocyte activation involved in immune response; GO:0019882 antigen processing and presentation; GO:0042119 neutrophil activation; GO:0050852 T cell receptor signaling pathway; GO:0002684 positive regulation of immune system process; GO:0038095 Fc-epsilon receptor signaling pathway; GO:0051248 negative regulation of protein metabolic process; GO:0022402 cell cycle process; GO:1902750 negative regulation of cell cycle G2/M phase transition; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0045321 leukocyte activation; GO:0002220 innate immune response activating cell surface receptor signaling pathway; GO:0007166 cell surface receptor signaling pathway; GO:0071345 cellular response to cytokine stimulus; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0051347 positive regulation of transferase activity; GO:0044419 interspecies interaction between organisms; GO:1903362 regulation of cellular protein catabolic process; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0002443 leukocyte mediated immunity; GO:0002758 innate immune response-activating signal transduction; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0031323 regulation of cellular metabolic process; GO:2000058 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0010948 negative regulation of cell cycle process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0002682 regulation of immune system process; GO:0031145 anaphase-promoting complex-dependent catabolic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0007346 regulation of mitotic cell cycle; GO:0002283 neutrophil activation involved in immune response; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:0051239 regulation of multicellular organismal process; GO:0031349 positive regulation of defense response; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:1901987 regulation of cell cycle phase transition; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0010389 regulation of G2/M transition of mitotic cell cycle; GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; GO:0009966 regulation of signal transduction; GO:0038061 NIK/NF-kappaB signaling; GO:0071456 cellular response to hypoxia; GO:0002253 activation of immune response; GO:0016192 vesicle-mediated transport; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1904666 regulation of ubiquitin protein ligase activity; GO:0055085 transmembrane transport; GO:0051247 positive regulation of protein metabolic process; GO:0051438 regulation of ubiquitin-protein transferase activity; GO:0030111 regulation of Wnt signaling pathway; GO:0006793 phosphorus metabolic process; GO:0001775 cell activation; GO:0036293 response to decreased oxygen levels; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process; GO:0006887 exocytosis; GO:0051444 negative regulation of ubiquitin-protein transferase activity; GO:0090090 negative regulation of canonical Wnt signaling pathway; GO:0044764 multi-organism cellular process; GO:0051234 establishment of localization; GO:0035567 non-canonical Wnt signaling pathway; GO:1905330 regulation of morphogenesis of an epithelium; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:1901991 negative regulation of mitotic cell cycle phase transition; GO:0045088 regulation of innate immune response; GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I; GO:0070887 cellular response to chemical stimulus; GO:0002274 myeloid leukocyte activation; GO:0050851 antigen receptor-mediated signaling pathway; GO:0010468 regulation of gene expression; GO:0030178 negative regulation of Wnt signaling pathway; GO:0048002 antigen processing and presentation of peptide antigen; GO:0002446 neutrophil mediated immunity; GO:0048522 positive regulation of cellular process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0051348 negative regulation of transferase activity; GO:0070647 protein modification by small protein conjugation or removal; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0042221 response to chemical; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0019222 regulation of metabolic process; GO:0043299 leukocyte degranulation; GO:2000026 regulation of multicellular organismal development; GO:0002218 activation of innate immune response; GO:1904667 negative regulation of ubiquitin protein ligase activity; GO:0002252 immune effector process; GO:0071356 cellular response to tumor necrosis factor; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0016579 protein deubiquitination; GO:1903322 positive regulation of protein modification by small protein conjugation or removal; GO:0006508 proteolysis; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:0033238 regulation of cellular amine metabolic process; GO:0043632 modification-dependent macromolecule catabolic process; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0045089 positive regulation of innate immune response; GO:0031401 positive regulation of protein modification process; GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0051246 regulation of protein metabolic process; GO:0009057 macromolecule catabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0009967 positive regulation of signal transduction; GO:0045732 positive regulation of protein catabolic process; GO:0036294 cellular response to decreased oxygen levels; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:1905369 endopeptidase complex; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:1905368 peptidase complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0000502 proteasome complex; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0005839 proteasome core complex; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0004175 endopeptidase activity; GO:0004298 threonine-type endopeptidase activity; GO:0008233 peptidase activity; GO:0070003 threonine-type peptidase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0016787 hydrolase activity; GO:0005515 protein binding; ","K02732","PSMB1; 20S proteasome subunit beta 6 [EC:3.4.25.1]","hsa03050 Proteasome - Homo sapiens (human); ","IPR029055; ","\"Nucleophile aminohydrolases, N-terminal; \"\r"]
["P20645","Cation-dependent mannose-6-phosphate receptor OS=Homo sapiens OX=9606 GN=M6PR","M6PR",30.993,16.039,18.8,4,5,4,0.959,0.999,0.91,0.997,1.087,1.058,1.096,0.0699,"extracellular\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0015749 monosaccharide transport; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0015031 protein transport; GO:0015761 mannose transport; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:1902578 single-organism localization; GO:0009306 protein secretion; GO:0008643 carbohydrate transport; GO:0006898 receptor-mediated endocytosis; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0009987 cellular process; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0007041 lysosomal transport; GO:0051716 cellular response to stimulus; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0071702 organic substance transport; GO:0006897 endocytosis; GO:0008333 endosome to lysosome transport; GO:0023052 signaling; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:0016197 endosomal transport; GO:0050789 regulation of biological process; GO:0032940 secretion by cell; GO:0008645 hexose transport; GO:0007034 vacuolar transport; GO:0033299 secretion of lysosomal enzymes; GO:0061024 membrane organization; GO:0051179 localization; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0031224 intrinsic component of membrane; GO:0032588 trans-Golgi network membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0030662 coated vesicle membrane; GO:0044422 organelle part; GO:0005765 lysosomal membrane; GO:0030136 clathrin-coated vesicle; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005764 lysosome; GO:0098805 whole membrane; GO:0098791 Golgi subcompartment; GO:0048471 perinuclear region of cytoplasm; GO:0044431 Golgi apparatus part; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0031226 intrinsic component of plasma membrane; GO:0005770 late endosome; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0030665 clathrin-coated vesicle membrane; GO:0030135 coated vesicle; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0098852 lytic vacuole membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044459 plasma membrane part; GO:0044437 vacuolar part; GO:0005802 trans-Golgi network; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0030133 transport vesicle; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; GO:0031984 organelle subcompartment; ","GO:0038023 signaling receptor activity; GO:0051119 sugar transmembrane transporter activity; GO:1901476 carbohydrate transporter activity; GO:0044877 macromolecular complex binding; GO:0022892 substrate-specific transporter activity; GO:0015145 monosaccharide transmembrane transporter activity; GO:0005515 protein binding; GO:0048029 monosaccharide binding; GO:0004888 transmembrane signaling receptor activity; GO:0004871 signal transducer activity; GO:1905394 retromer complex binding; GO:0022891 substrate-specific transmembrane transporter activity; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0015144 carbohydrate transmembrane transporter activity; GO:0015578 mannose transmembrane transporter activity; GO:0005488 binding; GO:0005537 mannose binding; GO:0015149 hexose transmembrane transporter activity; GO:0030246 carbohydrate binding; GO:0036094 small molecule binding; GO:0022857 transmembrane transporter activity; GO:0005215 transporter activity; GO:0099600 transmembrane receptor activity; GO:0032403 protein complex binding; ","K10089","M6PR; cation-dependent mannose-6-phosphate receptor","hsa04142 Lysosome - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); ","IPR009011; ","Mannose-6-phosphate receptor binding domain; \r"]
["P20674","Cytochrome c oxidase subunit 5A, mitochondrial OS=Homo sapiens OX=9606 GN=COX5A","COX5A",16.762,32.232,32.7,5,8,5,1.062,1.039,1.074,0.985,0.996,0.956,0.925,0.00756,"mitochondria\r","GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0006123 mitochondrial electron transport, cytochrome c to oxygen; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0006753 nucleoside phosphate metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0044765 single-organism transport; GO:0098655 cation transmembrane transport; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006119 oxidative phosphorylation; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0006810 transport; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0022900 electron transport chain; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0098662 inorganic cation transmembrane transport; GO:0016310 phosphorylation; GO:0034220 ion transmembrane transport; GO:0006725 cellular aromatic compound metabolic process; GO:0042773 ATP synthesis coupled electron transport; GO:0009259 ribonucleotide metabolic process; GO:0022904 respiratory electron transport chain; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:1902578 single-organism localization; GO:0006139 nucleobase-containing compound metabolic process; GO:0006812 cation transport; GO:1902600 hydrogen ion transmembrane transport; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009119 ribonucleoside metabolic process; GO:0009987 cellular process; GO:0046034 ATP metabolic process; GO:0098660 inorganic ion transmembrane transport; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0045333 cellular respiration; GO:0006163 purine nucleotide metabolic process; GO:0006818 hydrogen transport; GO:0015992 proton transport; GO:0046128 purine ribonucleoside metabolic process; GO:0055085 transmembrane transport; GO:0006793 phosphorus metabolic process; GO:0006811 ion transport; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0051179 localization; GO:0015672 monovalent inorganic cation transport; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0043209 myelin sheath; GO:0019866 organelle inner membrane; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0098803 respiratory chain complex; GO:0005751 mitochondrial respiratory chain complex IV; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0070069 cytochrome complex; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005746 mitochondrial respiratory chain; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0045277 respiratory chain complex IV; GO:0031975 envelope; GO:0043234 protein complex; GO:0070469 respiratory chain; GO:0043230 extracellular organelle; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0015075 ion transmembrane transporter activity; GO:0043167 ion binding; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0015077 monovalent inorganic cation transmembrane transporter activity; GO:0016676 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor; GO:0016675 oxidoreductase activity, acting on a heme group of donors; GO:0015078 hydrogen ion transmembrane transporter activity; GO:0015002 heme-copper terminal oxidase activity; GO:0016491 oxidoreductase activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0009055 electron carrier activity; GO:0004129 cytochrome-c oxidase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0022890 inorganic cation transmembrane transporter activity; GO:0008324 cation transmembrane transporter activity; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; ","K02264","COX5A; cytochrome c oxidase subunit 5a","hsa04260 Cardiac muscle contraction - Homo sapiens (human); hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); "]
["P20700","Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1","LMNB1",66.408,91.43,38.7,24,39,22,0.924,0.989,0.924,1.044,1.102,1.029,1.119,0.0216,"nucleus\r",null,"GO:0016020 membrane; GO:0031090 organelle membrane; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005652 nuclear lamina; GO:0005856 cytoskeleton; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0031965 nuclear membrane; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005637 nuclear inner membrane; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0005635 nuclear envelope; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0099081 supramolecular polymer; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0045111 intermediate filament cytoskeleton; GO:0005882 intermediate filament; GO:0031975 envelope; GO:0016363 nuclear matrix; GO:0005638 lamin filament; GO:0034399 nuclear periphery; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0043274 phospholipase binding; GO:0005198 structural molecule activity; GO:0005488 binding; GO:0019899 enzyme binding; ","K07611","LMNB; lamin B","hsa04210 Apoptosis - Homo sapiens (human); ","IPR001322; ","Lamin Tail Domain; \r"]
["P20774","Mimecan OS=Homo sapiens OX=9606 GN=OGN","OGN",33.922,84.869,31.9,9,32,9,1.112,1.084,1.076,0.897,0.91,0.855,0.814,0.000637,"extracellular\r","GO:0006024 glycosaminoglycan biosynthetic process; GO:0006026 aminoglycan catabolic process; GO:0048869 cellular developmental process; GO:0048666 neuron development; GO:0044699 single-organism process; GO:0032989 cellular component morphogenesis; GO:0022008 neurogenesis; GO:0009058 biosynthetic process; GO:0042340 keratan sulfate catabolic process; GO:0044237 cellular metabolic process; GO:0044272 sulfur compound biosynthetic process; GO:0030203 glycosaminoglycan metabolic process; GO:0008285 negative regulation of cell proliferation; GO:0042339 keratan sulfate metabolic process; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0032990 cell part morphogenesis; GO:0048858 cell projection morphogenesis; GO:0043170 macromolecule metabolic process; GO:0006790 sulfur compound metabolic process; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0048699 generation of neurons; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0048812 neuron projection morphogenesis; GO:0032501 multicellular organismal process; GO:0006027 glycosaminoglycan catabolic process; GO:0000902 cell morphogenesis; GO:1901575 organic substance catabolic process; GO:0050789 regulation of biological process; GO:0030030 cell projection organization; GO:0044710 single-organism metabolic process; GO:0044273 sulfur compound catabolic process; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:0043436 oxoacid metabolic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0042127 regulation of cell proliferation; GO:0048660 regulation of smooth muscle cell proliferation; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:1901566 organonitrogen compound biosynthetic process; GO:0048468 cell development; GO:0000904 cell morphogenesis involved in differentiation; GO:0071704 organic substance metabolic process; GO:0009653 anatomical structure morphogenesis; GO:0030154 cell differentiation; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0007409 axonogenesis; GO:0044248 cellular catabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0007275 multicellular organism development; GO:0009059 macromolecule biosynthetic process; GO:0006022 aminoglycan metabolic process; GO:0009987 cellular process; GO:1903510 mucopolysaccharide metabolic process; GO:0006023 aminoglycan biosynthetic process; GO:0044711 single-organism biosynthetic process; GO:0044712 single-organism catabolic process; GO:0048731 system development; GO:1901136 carbohydrate derivative catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0031175 neuron projection development; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0048662 negative regulation of smooth muscle cell proliferation; GO:0061564 axon development; GO:0030182 neuron differentiation; GO:1901565 organonitrogen compound catabolic process; GO:0044767 single-organism developmental process; GO:0009057 macromolecule catabolic process; GO:0018146 keratan sulfate biosynthetic process; GO:0009056 catabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0005796 Golgi lumen; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0043202 lysosomal lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031012 extracellular matrix; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005578 proteinaceous extracellular matrix; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0008083 growth factor activity; GO:0005515 protein binding; GO:0005102 receptor binding; GO:0005488 binding; ","K08126",null,null,"IPR032675; ","\"Leucine-rich repeat domain, L domain-like; \"\r"]
["P20810","Calpastatin OS=Homo sapiens OX=9606 GN=CAST","CAST",76.572,261.5,34.9,20,38,20,0.992,1.044,1.065,0.967,0.958,0.965,0.932,0.0816,"nucleus\r","GO:0050794 regulation of cellular process; GO:0010941 regulation of cell death; GO:0010951 negative regulation of endopeptidase activity; GO:0043069 negative regulation of programmed cell death; GO:0060255 regulation of macromolecule metabolic process; GO:0043067 regulation of programmed cell death; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0051346 negative regulation of hydrolase activity; GO:1904036 negative regulation of epithelial cell apoptotic process; GO:0010466 negative regulation of peptidase activity; GO:0043066 negative regulation of apoptotic process; GO:1904035 regulation of epithelial cell apoptotic process; GO:0052548 regulation of endopeptidase activity; GO:0045861 negative regulation of proteolysis; GO:0080090 regulation of primary metabolic process; GO:0030162 regulation of proteolysis; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0009892 negative regulation of metabolic process; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:2000674 regulation of type B pancreatic cell apoptotic process; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0051246 regulation of protein metabolic process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0065009 regulation of molecular function; GO:0051248 negative regulation of protein metabolic process; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0052547 regulation of peptidase activity; GO:0060548 negative regulation of cell death; GO:2000675 negative regulation of type B pancreatic cell apoptotic process; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0050839 cell adhesion molecule binding; GO:0003723 RNA binding; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0030414 peptidase inhibitor activity; GO:0061134 peptidase regulator activity; GO:0045296 cadherin binding; GO:0003676 nucleic acid binding; GO:0061135 endopeptidase regulator activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0004857 enzyme inhibitor activity; GO:0004866 endopeptidase inhibitor activity; GO:0004869 cysteine-type endopeptidase inhibitor activity; ","K04281"]
["P20851","C4b-binding protein beta chain OS=Homo sapiens OX=9606 GN=C4BPB","C4BPB",28.357,12.588,15.9,4,6,4,0.914,0.848,0.94,1.039,1.052,1.131,1.192,0.0122,"extracellular\r","GO:0060627 regulation of vesicle-mediated transport; GO:0030450 regulation of complement activation, classical pathway; GO:0016064 immunoglobulin mediated immune response; GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0002698 negative regulation of immune effector process; GO:1903318 negative regulation of protein maturation; GO:0045916 negative regulation of complement activation; GO:0044699 single-organism process; GO:0031347 regulation of defense response; GO:0009611 response to wounding; GO:0006956 complement activation; GO:0008152 metabolic process; GO:0002890 negative regulation of immunoglobulin mediated immune response; GO:0009893 positive regulation of metabolic process; GO:0032879 regulation of localization; GO:0002819 regulation of adaptive immune response; GO:0002250 adaptive immune response; GO:0006958 complement activation, classical pathway; GO:0050777 negative regulation of immune response; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0050764 regulation of phagocytosis; GO:0002697 regulation of immune effector process; GO:0010468 regulation of gene expression; GO:0002443 leukocyte mediated immunity; GO:0080090 regulation of primary metabolic process; GO:0009894 regulation of catabolic process; GO:0045959 negative regulation of complement activation, classical pathway; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0032501 multicellular organismal process; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0050776 regulation of immune response; GO:0002683 negative regulation of immune system process; GO:0002820 negative regulation of adaptive immune response; GO:0002889 regulation of immunoglobulin mediated immune response; GO:0002923 regulation of humoral immune response mediated by circulating immunoglobulin; GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0048583 regulation of response to stimulus; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0002682 regulation of immune system process; GO:0006952 defense response; GO:1903317 regulation of protein maturation; GO:0050817 coagulation; GO:0050794 regulation of cellular process; GO:0030449 regulation of complement activation; GO:0044707 single-multicellular organism process; GO:2000257 regulation of protein activation cascade; GO:0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0002704 negative regulation of leukocyte mediated immunity; GO:0010955 negative regulation of protein processing; GO:0002920 regulation of humoral immune response; GO:0002673 regulation of acute inflammatory response; GO:0006959 humoral immune response; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:0002921 negative regulation of humoral immune response; GO:0050896 response to stimulus; GO:0002706 regulation of lymphocyte mediated immunity; GO:0045087 innate immune response; GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0007599 hemostasis; GO:0019724 B cell mediated immunity; GO:0071704 organic substance metabolic process; GO:2000258 negative regulation of protein activation cascade; GO:0009896 positive regulation of catabolic process; GO:0002707 negative regulation of lymphocyte mediated immunity; GO:0042176 regulation of protein catabolic process; GO:0002449 lymphocyte mediated immunity; GO:0050778 positive regulation of immune response; GO:0002253 activation of immune response; GO:0045861 negative regulation of proteolysis; GO:0050878 regulation of body fluid levels; GO:0030100 regulation of endocytosis; GO:0006950 response to stress; GO:0010629 negative regulation of gene expression; GO:0051049 regulation of transport; GO:0002712 regulation of B cell mediated immunity; GO:0032101 regulation of response to external stimulus; GO:0072376 protein activation cascade; GO:0002376 immune system process; GO:0048585 negative regulation of response to stimulus; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0048518 positive regulation of biological process; GO:0002703 regulation of leukocyte mediated immunity; GO:0051247 positive regulation of protein metabolic process; GO:0042060 wound healing; GO:0051246 regulation of protein metabolic process; GO:1903027 regulation of opsonization; GO:0002684 positive regulation of immune system process; GO:0050727 regulation of inflammatory response; GO:0070613 regulation of protein processing; GO:0051248 negative regulation of protein metabolic process; GO:0045732 positive regulation of protein catabolic process; GO:0051128 regulation of cellular component organization; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0048584 positive regulation of response to stimulus; GO:0006955 immune response; GO:0002713 negative regulation of B cell mediated immunity; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044217 other organism part; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0071944 cell periphery; GO:0044216 other organism cell; GO:0044215 other organism; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; ","GO:0005515 protein binding; GO:0005488 binding; ","K04003","C4BPB; complement component 4 binding protein, beta","hsa05133 Pertussis - Homo sapiens (human); hsa04610 Complement and coagulation cascades - Homo sapiens (human); ","IPR000436; ","Sushi/SCR/CCP domain; \r"]
["P20908","Collagen alpha-1(V) chain OS=Homo sapiens OX=9606 GN=COL5A1","COL5A1",183.56,19.55,3.8,7,8,7,0.942,1.075,1.039,0.901,1.192,0.859,0.966,0.71,"extracellular\r","GO:0051093 negative regulation of developmental process; GO:0010256 endomembrane system organization; GO:0030199 collagen fibril organization; GO:0035989 tendon development; GO:0051674 localization of cell; GO:0001568 blood vessel development; GO:0032964 collagen biosynthetic process; GO:0044236 multicellular organism metabolic process; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0009611 response to wounding; GO:0022610 biological adhesion; GO:0048729 tissue morphogenesis; GO:0008152 metabolic process; GO:0007507 heart development; GO:0007155 cell adhesion; GO:0043170 macromolecule metabolic process; GO:0030198 extracellular matrix organization; GO:0061448 connective tissue development; GO:0045596 negative regulation of cell differentiation; GO:0044259 multicellular organismal macromolecule metabolic process; GO:0090596 sensory organ morphogenesis; GO:0030574 collagen catabolic process; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0043588 skin development; GO:0009888 tissue development; GO:0071822 protein complex subunit organization; GO:0090505 epiboly involved in wound healing; GO:0048592 eye morphogenesis; GO:0090504 epiboly; GO:0003007 heart morphogenesis; GO:0044763 single-organism cellular process; GO:0001944 vasculature development; GO:0007009 plasma membrane organization; GO:0048870 cell motility; GO:0032501 multicellular organismal process; GO:0044319 wound healing, spreading of cells; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0044710 single-organism metabolic process; GO:0009887 animal organ morphogenesis; GO:0040011 locomotion; GO:0048856 anatomical structure development; GO:0097435 supramolecular fiber organization; GO:1903224 regulation of endodermal cell differentiation; GO:2000026 regulation of multicellular organismal development; GO:0072359 circulatory system development; GO:0050794 regulation of cellular process; GO:0002009 morphogenesis of an epithelium; GO:0016477 cell migration; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:0071704 organic substance metabolic process; GO:0009653 anatomical structure morphogenesis; GO:0044243 multicellular organismal catabolic process; GO:0001654 eye development; GO:0045992 negative regulation of embryonic development; GO:0010470 regulation of gastrulation; GO:0043062 extracellular structure organization; GO:0007275 multicellular organism development; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0006950 response to stress; GO:0044711 single-organism biosynthetic process; GO:0044712 single-organism catabolic process; GO:0048731 system development; GO:0002011 morphogenesis of an epithelial sheet; GO:0044802 single-organism membrane organization; GO:0072358 cardiovascular system development; GO:1901576 organic substance biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:2000542 negative regulation of gastrulation; GO:0042060 wound healing; GO:0045995 regulation of embryonic development; GO:0044767 single-organism developmental process; GO:0061024 membrane organization; GO:0045112 integrin biosynthetic process; GO:1903225 negative regulation of endodermal cell differentiation; GO:0022603 regulation of anatomical structure morphogenesis; GO:0032963 collagen metabolic process; GO:0006928 movement of cell or subcellular component; GO:0035313 wound healing, spreading of epidermal cells; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0007423 sensory organ development; GO:0009056 catabolic process; GO:0050793 regulation of developmental process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0098643 banded collagen fibril; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0005583 fibrillar collagen trimer; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0044420 extracellular matrix component; GO:0005581 collagen trimer; GO:0044422 organelle part; GO:0005604 basement membrane; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005788 endoplasmic reticulum lumen; GO:0098644 complex of collagen trimers; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0099081 supramolecular polymer; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031012 extracellular matrix; GO:0005588 collagen type V trimer; GO:0044432 endoplasmic reticulum part; GO:0005578 proteinaceous extracellular matrix; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005102 receptor binding; GO:0019838 growth factor binding; GO:0043167 ion binding; GO:0044877 macromolecular complex binding; GO:0043394 proteoglycan binding; GO:0048407 platelet-derived growth factor binding; GO:0005515 protein binding; GO:0005178 integrin binding; GO:0008201 heparin binding; GO:1901681 sulfur compound binding; GO:0005201 extracellular matrix structural constituent; GO:0050839 cell adhesion molecule binding; GO:0097367 carbohydrate derivative binding; GO:0005488 binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0001948 glycoprotein binding; GO:0005539 glycosaminoglycan binding; GO:0005198 structural molecule activity; GO:0032403 protein complex binding; ","K19721","COL5AS; collagen, type V/XI/XXIV/XXVII, alpha","hsa04974 Protein digestion and absorption - Homo sapiens (human); ","IPR000885; IPR013320; IPR001791; ","\"Fibrillar collagen, C-terminal; Concanavalin A-like lectin/glucanase domain; Laminin G domain; \"\r"]
["P20933","N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase OS=Homo sapiens OX=9606 GN=AGA","AGA",37.208,50.037,12.7,3,5,3,0.988,1.04,1.008,0.99,0.99,0.976,0.974,0.166,"extracellular\r","GO:0045321 leukocyte activation; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0006517 protein deglycosylation; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:1901135 carbohydrate derivative metabolic process; GO:0006508 proteolysis; GO:0036230 granulocyte activation; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0009987 cellular process; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0002443 leukocyte mediated immunity; GO:0016192 vesicle-mediated transport; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0009100 glycoprotein metabolic process; GO:0002376 immune system process; GO:0043312 neutrophil degranulation; GO:0044238 primary metabolic process; GO:0002263 cell activation involved in immune response; GO:0002444 myeloid leukocyte mediated immunity; GO:0006810 transport; GO:0002366 leukocyte activation involved in immune response; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:0032940 secretion by cell; GO:0044260 cellular macromolecule metabolic process; GO:0001775 cell activation; GO:0006464 cellular protein modification process; GO:0010467 gene expression; GO:0043299 leukocyte degranulation; GO:0051179 localization; GO:0006955 immune response; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:0051604 protein maturation; GO:0006887 exocytosis; ","GO:0034774 secretory granule lumen; GO:0005615 extracellular space; GO:0005783 endoplasmic reticulum; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0042582 azurophil granule; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0008233 peptidase activity; GO:0043621 protein self-association; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0003948 N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity; GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; ","K01444","AGA; N4-(beta-N-acetylglucosaminyl)-L-asparaginase [EC:3.5.1.26]","hsa04142 Lysosome - Homo sapiens (human); hsa00511 Other glycan degradation - Homo sapiens (human); ","IPR029055; ","\"Nucleophile aminohydrolases, N-terminal; \"\r"]
["P21128","Poly(U)-specific endoribonuclease OS=Homo sapiens OX=9606 GN=ENDOU","ENDOU",46.872,2.6157,2.7,1,1,1,1.075,1.087,0.768,0.872,1.249,0.957,1.051,0.766,"extracellular\r","GO:0000003 reproduction; GO:0006725 cellular aromatic compound metabolic process; GO:0022414 reproductive process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:0071704 organic substance metabolic process; GO:0007565 female pregnancy; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0044706 multi-multicellular organism process; GO:0034641 cellular nitrogen compound metabolic process; GO:0006508 proteolysis; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0006898 receptor-mediated endocytosis; GO:0009987 cellular process; GO:0016192 vesicle-mediated transport; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:0006897 endocytosis; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0016070 RNA metabolic process; GO:0090501 RNA phosphodiester bond hydrolysis; GO:0090304 nucleic acid metabolic process; GO:0044703 multi-organism reproductive process; GO:0044260 cellular macromolecule metabolic process; GO:0006955 immune response; GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic; GO:0051179 localization; GO:0090305 nucleic acid phosphodiester bond hydrolysis; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; ","GO:0003723 RNA binding; GO:0008083 growth factor activity; GO:0008233 peptidase activity; GO:0005102 receptor binding; GO:0043167 ion binding; GO:0008236 serine-type peptidase activity; GO:0004521 endoribonuclease activity; GO:0038024 cargo receptor activity; GO:0005044 scavenger receptor activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0030145 manganese ion binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0060089 molecular transducer activity; GO:0030247 polysaccharide binding; GO:0004872 receptor activity; GO:0046914 transition metal ion binding; GO:0017171 serine hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0003676 nucleic acid binding; GO:0004518 nuclease activity; GO:0030246 carbohydrate binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0001871 pattern binding; GO:0004540 ribonuclease activity; GO:0004519 endonuclease activity; ","K14648",null,null,"IPR020436; IPR001212; ","\"Somatomedin B, chordata; Somatomedin B domain; \"\r"]
["P21266","Glutathione S-transferase Mu 3 OS=Homo sapiens OX=9606 GN=GSTM3","GSTM3",26.559,53.376,45.3,13,26,11,1.099,1.119,1.105,0.886,0.879,0.909,0.805,4.27e-05,"cytoplasm\r","GO:0006518 peptide metabolic process; GO:0043627 response to estrogen; GO:0051410 detoxification of nitrogen compound; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0045446 endothelial cell differentiation; GO:0044237 cellular metabolic process; GO:0044272 sulfur compound biosynthetic process; GO:0008152 metabolic process; GO:1901685 glutathione derivative metabolic process; GO:0006749 glutathione metabolic process; GO:0007422 peripheral nervous system development; GO:0070887 cellular response to chemical stimulus; GO:0006790 sulfur compound metabolic process; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0051716 cellular response to stimulus; GO:0002064 epithelial cell development; GO:0009888 tissue development; GO:0070458 cellular detoxification of nitrogen compound; GO:0009636 response to toxic substance; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0032501 multicellular organismal process; GO:0042221 response to chemical; GO:0044710 single-organism metabolic process; GO:1901698 response to nitrogen compound; GO:0098754 detoxification; GO:0048856 anatomical structure development; GO:0030855 epithelial cell differentiation; GO:0071466 cellular response to xenobiotic stimulus; GO:0044707 single-multicellular organism process; GO:0033554 cellular response to stress; GO:0008065 establishment of blood-nerve barrier; GO:0006725 cellular aromatic compound metabolic process; GO:0050896 response to stimulus; GO:1901566 organonitrogen compound biosynthetic process; GO:0048468 cell development; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:1990748 cellular detoxification; GO:0009410 response to xenobiotic stimulus; GO:0006805 xenobiotic metabolic process; GO:0006575 cellular modified amino acid metabolic process; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0042537 benzene-containing compound metabolic process; GO:0006950 response to stress; GO:0044711 single-organism biosynthetic process; GO:0048731 system development; GO:0006807 nitrogen compound metabolic process; GO:1901576 organic substance biosynthetic process; GO:0003158 endothelium development; GO:0044249 cellular biosynthetic process; GO:1901687 glutathione derivative biosynthetic process; GO:0042178 xenobiotic catabolic process; GO:0044767 single-organism developmental process; GO:0001885 endothelial cell development; GO:0009056 catabolic process; GO:0018916 nitrobenzene metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0005929 cilium; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0036126 sperm flagellum; GO:0097729 9+2 motile cilium; GO:0044424 intracellular part; GO:0044463 cell projection part; GO:0031514 motile cilium; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005634 nucleus; GO:0044441 ciliary part; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0097223 sperm part; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0035686 sperm fibrous sheath; ","GO:0046983 protein dimerization activity; GO:0043167 ion binding; GO:0005515 protein binding; GO:0033218 amide binding; GO:0043295 glutathione binding; GO:1900750 oligopeptide binding; GO:1901681 sulfur compound binding; GO:0004364 glutathione transferase activity; GO:0072341 modified amino acid binding; GO:0042802 identical protein binding; GO:0042277 peptide binding; GO:0003824 catalytic activity; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups; GO:0043168 anion binding; GO:0016740 transferase activity; GO:0019899 enzyme binding; ","K00799","GST; glutathione S-transferase [EC:2.5.1.18]","hsa01524 Platinum drug resistance - Homo sapiens (human); hsa00480 Glutathione metabolism - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa05204 Chemical carcinogenesis - Homo sapiens (human); hsa00980 Metabolism of xenobiotics by cytochrome P450 - Homo sapiens (human); hsa05225 Hepatocellular carcinoma - Homo sapiens (human); hsa00983 Drug metabolism - other enzymes - Homo sapiens (human); hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human); hsa00982 Drug metabolism - cytochrome P450 - Homo sapiens (human); hsa05215 Prostate cancer - Homo sapiens (human); ","IPR004046; IPR010987; IPR012336; IPR004045; ","\"Glutathione S-transferase, C-terminal; Glutathione S-transferase, C-terminal-like; Thioredoxin-like fold; Glutathione S-transferase, N-terminal; \"\r"]
["P21281","V-type proton ATPase subunit B, brain isoform OS=Homo sapiens OX=9606 GN=ATP6V1B2","ATP6V1B2",56.5,88.105,31.5,12,13,6,0.915,0.934,0.9,1.107,1.03,1.107,1.18,3.3E-3,"mitochondria\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0009116 nucleoside metabolic process; GO:0007166 cell surface receptor signaling pathway; GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient; GO:0030641 regulation of cellular pH; GO:0030004 cellular monovalent inorganic cation homeostasis; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0000041 transition metal ion transport; GO:0008152 metabolic process; GO:0009719 response to endogenous stimulus; GO:0019693 ribose phosphate metabolic process; GO:0008104 protein localization; GO:1901652 response to peptide; GO:0044765 single-organism transport; GO:0051716 cellular response to stimulus; GO:0090383 phagosome acidification; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0033572 transferrin transport; GO:0010506 regulation of autophagy; GO:0016241 regulation of macroautophagy; GO:0006810 transport; GO:0010243 response to organonitrogen compound; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:1901698 response to nitrogen compound; GO:0032869 cellular response to insulin stimulus; GO:0009126 purine nucleoside monophosphate metabolic process; GO:0098662 inorganic cation transmembrane transport; GO:0050794 regulation of cellular process; GO:0034220 ion transmembrane transport; GO:0006885 regulation of pH; GO:0030001 metal ion transport; GO:0009259 ribonucleotide metabolic process; GO:1901700 response to oxygen-containing compound; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0099131 ATP hydrolysis coupled ion transmembrane transport; GO:0009119 ribonucleoside metabolic process; GO:0048878 chemical homeostasis; GO:0071702 organic substance transport; GO:0009141 nucleoside triphosphate metabolic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0006163 purine nucleotide metabolic process; GO:0045184 establishment of protein localization; GO:0072512 trivalent inorganic cation transport; GO:0055085 transmembrane transport; GO:0006873 cellular ion homeostasis; GO:0051453 regulation of intracellular pH; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0006811 ion transport; GO:0019637 organophosphate metabolic process; GO:0051179 localization; GO:0015672 monovalent inorganic cation transport; GO:1901564 organonitrogen compound metabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0008286 insulin receptor signaling pathway; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0090662 ATP hydrolysis coupled transmembrane transport; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:1901653 cellular response to peptide; GO:0007154 cell communication; GO:0006753 nucleoside phosphate metabolic process; GO:0033036 macromolecule localization; GO:0070887 cellular response to chemical stimulus; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0098655 cation transmembrane transport; GO:0050801 ion homeostasis; GO:0015682 ferric iron transport; GO:0098771 inorganic ion homeostasis; GO:1901360 organic cyclic compound metabolic process; GO:0019725 cellular homeostasis; GO:0023052 signaling; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0071417 cellular response to organonitrogen compound; GO:0050789 regulation of biological process; GO:0032868 response to insulin; GO:0042221 response to chemical; GO:0043434 response to peptide hormone; GO:1901699 cellular response to nitrogen compound; GO:0032870 cellular response to hormone stimulus; GO:0019222 regulation of metabolic process; GO:0015991 ATP hydrolysis coupled proton transport; GO:1901657 glycosyl compound metabolic process; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0045851 pH reduction; GO:0071310 cellular response to organic substance; GO:0030003 cellular cation homeostasis; GO:0006826 iron ion transport; GO:0050896 response to stimulus; GO:0055082 cellular chemical homeostasis; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0055080 cation homeostasis; GO:0006812 cation transport; GO:0071375 cellular response to peptide hormone stimulus; GO:1902600 hydrogen ion transmembrane transport; GO:0034641 cellular nitrogen compound metabolic process; GO:0099132 ATP hydrolysis coupled cation transmembrane transport; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0009987 cellular process; GO:0046034 ATP metabolic process; GO:0090382 phagosome maturation; GO:0055067 monovalent inorganic cation homeostasis; GO:0098660 inorganic ion transmembrane transport; GO:0006807 nitrogen compound metabolic process; GO:0015992 proton transport; GO:0006818 hydrogen transport; GO:0046128 purine ribonucleoside metabolic process; GO:1901701 cellular response to oxygen-containing compound; GO:0071495 cellular response to endogenous stimulus; GO:0009150 purine ribonucleotide metabolic process; GO:0051452 intracellular pH reduction; GO:0009725 response to hormone; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0033176 proton-transporting V-type ATPase complex; GO:0098858 actin-based cell projection; GO:0005623 cell; GO:0044422 organelle part; GO:0048770 pigment granule; GO:0005765 lysosomal membrane; GO:0070062 extracellular exosome; GO:0043209 myelin sheath; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0000323 lytic vacuole; GO:0031252 cell leading edge; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0042995 cell projection; GO:0098588 bounding membrane of organelle; GO:0042470 melanosome; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0033180 proton-transporting V-type ATPase, V1 domain; GO:0005886 plasma membrane; GO:0098852 lytic vacuole membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044437 vacuolar part; GO:0016469 proton-transporting two-sector ATPase complex; GO:0005902 microvillus; GO:0005773 vacuole; GO:0001726 ruffle; GO:0005774 vacuolar membrane; GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0042625 ATPase coupled ion transmembrane transporter activity; GO:1901265 nucleoside phosphate binding; GO:0015399 primary active transmembrane transporter activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism; GO:0022892 substrate-specific transporter activity; GO:0015077 monovalent inorganic cation transmembrane transporter activity; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0015078 hydrogen ion transmembrane transporter activity; GO:0016887 ATPase activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0019829 cation-transporting ATPase activity; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0043492 ATPase activity, coupled to movement of substances; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0036442 hydrogen-exporting ATPase activity; GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0022890 inorganic cation transmembrane transporter activity; GO:0005215 transporter activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0022804 active transmembrane transporter activity; GO:0005524 ATP binding; GO:0015075 ion transmembrane transporter activity; GO:0022853 active ion transmembrane transporter activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0046961 proton-transporting ATPase activity, rotational mechanism; GO:0032549 ribonucleoside binding; GO:0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity; GO:0097367 carbohydrate derivative binding; GO:0042626 ATPase activity, coupled to transmembrane movement of substances; GO:0042623 ATPase activity, coupled; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0008324 cation transmembrane transporter activity; GO:0036094 small molecule binding; GO:0022857 transmembrane transporter activity; ","K02147","ATPeV1B; V-type H+-transporting ATPase subunit B","hsa05120 Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human); hsa04966 Collecting duct acid secretion - Homo sapiens (human); hsa05323 Rheumatoid arthritis - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa04150 mTOR signaling pathway - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05110 Vibrio cholerae infection - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); hsa04721 Synaptic vesicle cycle - Homo sapiens (human); ","IPR004100; IPR000194; IPR027417; ","\"ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain; ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain; P-loop containing nucleoside triphosphate hydrolase; \"\r"]
["P21283","V-type proton ATPase subunit C 1 OS=Homo sapiens OX=9606 GN=ATP6V1C1","ATP6V1C1",43.941,19.65,22.5,10,14,9,0.947,0.949,0.9,1.068,1.02,1.058,1.125,0.0061,"cytoplasm\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0008286 insulin receptor signaling pathway; GO:0007166 cell surface receptor signaling pathway; GO:0090662 ATP hydrolysis coupled transmembrane transport; GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient; GO:0030641 regulation of cellular pH; GO:0030004 cellular monovalent inorganic cation homeostasis; GO:0044699 single-organism process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0000041 transition metal ion transport; GO:0007165 signal transduction; GO:1901653 cellular response to peptide; GO:0007154 cell communication; GO:0009719 response to endogenous stimulus; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:1901652 response to peptide; GO:0070887 cellular response to chemical stimulus; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0044765 single-organism transport; GO:0051716 cellular response to stimulus; GO:0098655 cation transmembrane transport; GO:0050801 ion homeostasis; GO:0015682 ferric iron transport; GO:0090383 phagosome acidification; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0098771 inorganic ion homeostasis; GO:0044763 single-organism cellular process; GO:0019725 cellular homeostasis; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0031323 regulation of cellular metabolic process; GO:0033572 transferrin transport; GO:0023052 signaling; GO:0010506 regulation of autophagy; GO:0016241 regulation of macroautophagy; GO:0006810 transport; GO:0071417 cellular response to organonitrogen compound; GO:0010243 response to organonitrogen compound; GO:0050789 regulation of biological process; GO:0032868 response to insulin; GO:0042221 response to chemical; GO:0043434 response to peptide hormone; GO:1901699 cellular response to nitrogen compound; GO:0032870 cellular response to hormone stimulus; GO:1901698 response to nitrogen compound; GO:0032869 cellular response to insulin stimulus; GO:0015991 ATP hydrolysis coupled proton transport; GO:0019222 regulation of metabolic process; GO:0098662 inorganic cation transmembrane transport; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0034220 ion transmembrane transport; GO:0045851 pH reduction; GO:0006885 regulation of pH; GO:0030001 metal ion transport; GO:0071310 cellular response to organic substance; GO:0030003 cellular cation homeostasis; GO:1901700 response to oxygen-containing compound; GO:0006826 iron ion transport; GO:0050896 response to stimulus; GO:0055082 cellular chemical homeostasis; GO:0042592 homeostatic process; GO:1902578 single-organism localization; GO:0006812 cation transport; GO:0055080 cation homeostasis; GO:0071375 cellular response to peptide hormone stimulus; GO:1902600 hydrogen ion transmembrane transport; GO:0099132 ATP hydrolysis coupled cation transmembrane transport; GO:0099131 ATP hydrolysis coupled ion transmembrane transport; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0090382 phagosome maturation; GO:0055067 monovalent inorganic cation homeostasis; GO:0098660 inorganic ion transmembrane transport; GO:0071702 organic substance transport; GO:0010033 response to organic substance; GO:0006818 hydrogen transport; GO:0015992 proton transport; GO:0045184 establishment of protein localization; GO:0072512 trivalent inorganic cation transport; GO:0055085 transmembrane transport; GO:1901701 cellular response to oxygen-containing compound; GO:0051453 regulation of intracellular pH; GO:0006873 cellular ion homeostasis; GO:0071495 cellular response to endogenous stimulus; GO:0006811 ion transport; GO:0006996 organelle organization; GO:0051452 intracellular pH reduction; GO:0009725 response to hormone; GO:0051179 localization; GO:0015672 monovalent inorganic cation transport; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0033176 proton-transporting V-type ATPase complex; GO:0005623 cell; GO:0044422 organelle part; GO:0005765 lysosomal membrane; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0045177 apical part of cell; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0016471 vacuolar proton-transporting V-type ATPase complex; GO:0033180 proton-transporting V-type ATPase, V1 domain; GO:0005886 plasma membrane; GO:0098852 lytic vacuole membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044437 vacuolar part; GO:0016469 proton-transporting two-sector ATPase complex; GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0042625 ATPase coupled ion transmembrane transporter activity; GO:0015399 primary active transmembrane transporter activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism; GO:0022892 substrate-specific transporter activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0015077 monovalent inorganic cation transmembrane transporter activity; GO:0015078 hydrogen ion transmembrane transporter activity; GO:0016887 ATPase activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0019829 cation-transporting ATPase activity; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0043492 ATPase activity, coupled to movement of substances; GO:0005488 binding; GO:0036442 hydrogen-exporting ATPase activity; GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0022890 inorganic cation transmembrane transporter activity; GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism; GO:0005215 transporter activity; GO:0022804 active transmembrane transporter activity; GO:0015075 ion transmembrane transporter activity; GO:0022853 active ion transmembrane transporter activity; GO:0017111 nucleoside-triphosphatase activity; GO:0046961 proton-transporting ATPase activity, rotational mechanism; GO:0015662 ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism; GO:0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity; GO:0042626 ATPase activity, coupled to transmembrane movement of substances; GO:0042623 ATPase activity, coupled; GO:0008324 cation transmembrane transporter activity; GO:0022857 transmembrane transporter activity; ","K02148","ATPeV1C; V-type H+-transporting ATPase subunit C","hsa05120 Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human); hsa04966 Collecting duct acid secretion - Homo sapiens (human); hsa05323 Rheumatoid arthritis - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa04150 mTOR signaling pathway - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05110 Vibrio cholerae infection - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); hsa04721 Synaptic vesicle cycle - Homo sapiens (human); "]
["P21291","Cysteine and glycine-rich protein 1 OS=Homo sapiens OX=9606 GN=CSRP1","CSRP1",20.567,154.36,67.9,10,33,10,1.114,1.117,1.124,0.864,0.907,0.908,0.799,1.75E-4,"nucleus\r","GO:0044707 single-multicellular organism process; GO:0065008 regulation of biological quality; GO:0007596 blood coagulation; GO:0050878 regulation of body fluid levels; GO:0006950 response to stress; GO:0030168 platelet activation; GO:0044763 single-organism cellular process; GO:0098609 cell-cell adhesion; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0034109 homotypic cell-cell adhesion; GO:0032501 multicellular organismal process; GO:0007599 hemostasis; GO:0009611 response to wounding; GO:0022610 biological adhesion; GO:0016337 single organismal cell-cell adhesion; GO:0042060 wound healing; GO:0098602 single organism cell adhesion; GO:0001775 cell activation; GO:0007155 cell adhesion; GO:0050817 coagulation; GO:0009987 cellular process; GO:0070527 platelet aggregation; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0030054 cell junction; GO:0031982 vesicle; GO:0070161 anchoring junction; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0005924 cell-substrate adherens junction; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0046914 transition metal ion binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0043167 ion binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0008270 zinc ion binding; ","K09377",null,null,"IPR001781; ","\"Zinc finger, LIM-type; \"\r"]
["P21333","Filamin-A OS=Homo sapiens OX=9606 GN=FLNA","FLNA",280.74,323.31,54.6,117,289,104,1.067,1.067,1.069,0.938,0.93,0.935,0.875,4.16e-07,"cytoplasm\r",{"$cut":{"chars":16698,"head":"GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0010941 regulation of cell death; GO:0098910 regulation of atrial cardiac muscle cell action potential; GO:0044237 cellular metabolic process; GO:0044782 cilium organization; GO:0021932 hindbrain radial glia guided cell migration; GO:0008152 metabolic process; GO:1905031 regulation of membrane repolarization during cardiac muscle cell action potential; GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling; GO:1903115 regulation of actin filament-based movement; GO:0044057 regulation of system process; GO:0051220 cytoplasmic sequestering of protein; GO:0051716 cellular response to stimulus; GO:0000278 mitotic cell cycle; GO:0030168 platelet activation; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0007212 dopamine receptor signaling pathway; GO:1900026 positive regulation of substrate adhesion-dependent cell spreading; GO:0044763 single-organism cellular process; GO:0048870 cell motility; GO:0010811 positive regulation of cell-substrate adhesion; GO:0006810 transport; GO:0000226 microtubule cytoskeleton organization; GO:0031532 actin cytoskeleton reorganization; GO:0043113 receptor clustering; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0098602 single organism cell adhesion; GO:2000179 positive regulation of neural precursor cell proliferation; GO:0051223 regulation of protein transport; GO:0090307 mitotic spindle assembly; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0016071 mRNA metabolic process; GO:0060548 negative regulation of cell death; GO:0042307 positive regulation of protein import into nucleus; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0002009 morphogenesis of an epithelium; GO:0044707 single-multicellular organism process; GO:0002576 platelet degranulation; GO:0007051 spindle organization; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0042990 regulation of transcription factor import into nucleus; GO:0045892 negative regulation of transcription, DNA-templated; GO:0009653 anatomical structure morphogenesis; GO:0046483 heterocycle metabolic process; GO:0009299 mRNA transcription; GO:0006139 nucleobase-containing compound metabolic process; GO:2000145 regulation of cell motility; GO:0009889 regulation of biosynthetic process; GO:0010959 regulation of metal ion transport; GO:1902580 single-organism cellular localization; GO:0042176 regulation of protein catabolic process; GO:0034613 cellular protein localization; GO:0030902 hindbrain development; GO:1901381 positive regulation of potassium ion transmembrane transport; GO:0045785 positive regulation of cell adhesion; GO:0006950 response to stress; GO:0051270 regulation of cellular component movement; GO:0042789 mRNA transcription from RNA polymerase II promoter; GO:0051960 regulation of nervous system development; GO:1901379 regulation of potassium ion transmembrane transport; GO:0060284 regulation of cell development; GO:0032970 regulation of actin filament-based process; GO:1901576 organic substance biosynthetic process; GO:0007186 G-protein coupled receptor signaling pathway; GO:1900182 positive regulation of protein localization to nucleus; GO:0009890 negative regulation of biosynthetic process; GO:0072659 protein localization to plasma membrane; GO:0045055 regulated exocytosis; GO:1904064 positive regulation of cation transmembrane transport; GO:0006996 organelle organization; GO:0000280 nuclear division; GO:0031647 regulation of protein stability; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:0050821 protein stabilization; GO:1903827 regulation of cellular protein localization; GO:2001224 positive regulation of neuron migration; GO:0008284 positive regulation of cell proliferation; GO:0010256 endomembrane system organization; GO:0051674 localization of cell; GO:0043433 negative regulation of sequence-specific DNA binding transcripti"}},"GO:0030425 dendrite; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0099568 cytoplasmic region; GO:0005737 cytoplasm; GO:0043025 neuronal cell body; GO:0032991 macromolecular complex; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0031674 I band; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0043005 neuron projection; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043233 organelle lumen; GO:0005924 cell-substrate adherens junction; GO:0042995 cell projection; GO:0099513 polymeric cytoskeletal fiber; GO:0044430 cytoskeletal part; GO:0070161 anchoring junction; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005576 extracellular region; GO:0099081 supramolecular polymer; GO:0005886 plasma membrane; GO:0031012 extracellular matrix; GO:0043231 intracellular membrane-bounded organelle; GO:0044449 contractile fiber part; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0005938 cell cortex; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0030016 myofibril; GO:0031982 vesicle; GO:0030863 cortical cytoskeleton; GO:0044424 intracellular part; GO:0099512 supramolecular fiber; GO:0030018 Z disc; GO:0005911 cell-cell junction; GO:0044427 chromosomal part; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0031523 Myb complex; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005694 chromosome; GO:1903561 extracellular vesicle; GO:0005912 adherens junction; GO:0043292 contractile fiber; GO:0048471 perinuclear region of cytoplasm; GO:0005884 actin filament; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0044463 cell projection part; GO:0005829 cytosol; GO:0015629 actin cytoskeleton; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0005634 nucleus; GO:0044448 cell cortex part; GO:0097440 apical dendrite; GO:0030017 sarcomere; GO:0043198 dendritic shaft; GO:0044297 cell body; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0051015 actin filament binding; GO:0048365 Rac GTPase binding; GO:0005102 receptor binding; GO:0046983 protein dimerization activity; GO:0099106 ion channel regulator activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0004871 signal transducer activity; GO:0017160 Ral GTPase binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0042802 identical protein binding; GO:0008092 cytoskeletal protein binding; GO:0016247 channel regulator activity; GO:0017016 Ras GTPase binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0034987 immunoglobulin receptor binding; GO:0001664 G-protein coupled receptor binding; GO:0051020 GTPase binding; GO:0031267 small GTPase binding; GO:0017048 Rho GTPase binding; GO:0003723 RNA binding; GO:0044877 macromolecular complex binding; GO:0031628 opioid receptor binding; GO:0034988 Fc-gamma receptor I complex binding; GO:0019900 kinase binding; GO:0050839 cell adhesion molecule binding; GO:0097367 carbohydrate derivative binding; GO:0031852 mu-type opioid receptor binding; GO:0015459 potassium channel regulator activity; GO:0042803 protein homodimerization activity; GO:0003676 nucleic acid binding; GO:0003779 actin binding; GO:0044325 ion channel binding; GO:0001948 glycoprotein binding; GO:0046332 SMAD binding; GO:0019899 enzyme binding; GO:0008134 transcription factor binding; GO:0032403 protein complex binding; ","K04437","FLNA; filamin","hsa05132 Salmonella infection - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa04010 MAPK signaling pathway - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); ","IPR013783; IPR014756; IPR001715; ","Immunoglobulin-like fold; Immunoglobulin E-set; Calponin homology domain; \r"]
["P21397","Amine oxidase [flavin-containing] A OS=Homo sapiens OX=9606 GN=MAOA","MAOA",59.681,36.707,22.6,11,15,9,1.11,1.025,1.034,0.94,0.973,0.933,0.898,0.0195,"cytoplasm\r","GO:0001505 regulation of neurotransmitter levels; GO:0065008 regulation of biological quality; GO:0006725 cellular aromatic compound metabolic process; GO:1901615 organic hydroxy compound metabolic process; GO:0019614 catechol-containing compound catabolic process; GO:0097164 ammonium ion metabolic process; GO:0044699 single-organism process; GO:0042135 neurotransmitter catabolic process; GO:0044237 cellular metabolic process; GO:0006576 cellular biogenic amine metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:1901616 organic hydroxy compound catabolic process; GO:0042133 neurotransmitter metabolic process; GO:0042424 catecholamine catabolic process; GO:0044248 cellular catabolic process; GO:1901361 organic cyclic compound catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009987 cellular process; GO:0009308 amine metabolic process; GO:0044106 cellular amine metabolic process; GO:0055114 oxidation-reduction process; GO:0042420 dopamine catabolic process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0042417 dopamine metabolic process; GO:0009712 catechol-containing compound metabolic process; GO:0006584 catecholamine metabolic process; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:1901565 organonitrogen compound catabolic process; GO:0044710 single-organism metabolic process; GO:0018958 phenol-containing compound metabolic process; GO:0019336 phenol-containing compound catabolic process; GO:0009056 catabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0019867 outer membrane; GO:0044429 mitochondrial part; GO:0098588 bounding membrane of organelle; GO:0031090 organelle membrane; GO:0005741 mitochondrial outer membrane; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005740 mitochondrial envelope; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0031975 envelope; GO:0098805 whole membrane; GO:0031968 organelle outer membrane; GO:0043227 membrane-bounded organelle; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0008131 primary amine oxidase activity; GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors; GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor; GO:0003824 catalytic activity; GO:0016491 oxidoreductase activity; ","K00274","MAO; monoamine oxidase [EC:1.4.3.4]","hsa04728 Dopaminergic synapse - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa05031 Amphetamine addiction - Homo sapiens (human); hsa00330 Arginine and proline metabolism - Homo sapiens (human); hsa00340 Histidine metabolism - Homo sapiens (human); hsa00360 Phenylalanine metabolism - Homo sapiens (human); hsa00350 Tyrosine metabolism - Homo sapiens (human); hsa00380 Tryptophan metabolism - Homo sapiens (human); hsa05034 Alcoholism - Homo sapiens (human); hsa00982 Drug metabolism - cytochrome P450 - Homo sapiens (human); hsa05030 Cocaine addiction - Homo sapiens (human); hsa00260 Glycine, serine and threonine metabolism - Homo sapiens (human); hsa04726 Serotonergic synapse - Homo sapiens (human); ","IPR002937; IPR023753; ","Amine oxidase; FAD/NAD(P)-binding domain; \r"]
["P21399","Cytoplasmic aconitate hydratase OS=Homo sapiens OX=9606 GN=ACO1","ACO1",98.398,127.87,29.8,23,36,23,1.146,1.149,1.135,0.915,0.878,0.849,0.77,0.000283,"cytoplasm\r","GO:0065008 regulation of biological quality; GO:0007586 digestion; GO:0010608 posttranscriptional regulation of gene expression; GO:0050892 intestinal absorption; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0055065 metal ion homeostasis; GO:0010035 response to inorganic substance; GO:0032502 developmental process; GO:0072350 tricarboxylic acid metabolic process; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0050801 ion homeostasis; GO:0080090 regulation of primary metabolic process; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0098771 inorganic ion homeostasis; GO:0019725 cellular homeostasis; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0010040 response to iron(II) ion; GO:0010038 response to metal ion; GO:0046916 cellular transition metal ion homeostasis; GO:0006101 citrate metabolic process; GO:0006810 transport; GO:0032268 regulation of cellular protein metabolic process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0019222 regulation of metabolic process; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:0043436 oxoacid metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0006879 cellular iron ion homeostasis; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0055076 transition metal ion homeostasis; GO:0060255 regulation of macromolecule metabolic process; GO:0030003 cellular cation homeostasis; GO:0055072 iron ion homeostasis; GO:0009791 post-embryonic development; GO:0050896 response to stimulus; GO:0055082 cellular chemical homeostasis; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0055080 cation homeostasis; GO:0010039 response to iron ion; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0003008 system process; GO:0006099 tricarboxylic acid cycle; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:0045333 cellular respiration; GO:0034248 regulation of cellular amide metabolic process; GO:0006873 cellular ion homeostasis; GO:0051246 regulation of protein metabolic process; GO:0006417 regulation of translation; GO:0009060 aerobic respiration; GO:0044767 single-organism developmental process; GO:0022600 digestive system process; GO:0019752 carboxylic acid metabolic process; GO:0006875 cellular metal ion homeostasis; GO:0051179 localization; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0005794 Golgi apparatus; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0003723 RNA binding; GO:0043167 ion binding; GO:0003994 aconitate hydratase activity; GO:0016829 lyase activity; GO:0005515 protein binding; GO:0016836 hydro-lyase activity; GO:0051539 4 iron, 4 sulfur cluster binding; GO:0016835 carbon-oxygen lyase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0003729 mRNA binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0051536 iron-sulfur cluster binding; GO:0003676 nucleic acid binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0030350 iron-responsive element binding; GO:0051540 metal cluster binding; ","K01681","ACO; aconitate hydratase [EC:4.2.1.3]","hsa01210 2-Oxocarboxylic acid metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00020 Citrate cycle (TCA cycle) - Homo sapiens (human); hsa01230 Biosynthesis of amino acids - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); hsa00630 Glyoxylate and dicarboxylate metabolism - Homo sapiens (human); ","IPR001030; IPR000573; IPR015928; IPR015932; IPR015931; ","\"Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain; Aconitase A/isopropylmalate dehydratase small subunit, swivel domain; Aconitase/3-isopropylmalate dehydratase, swivel; Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2; Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3; \"\r"]
["P21589","5'-nucleotidase OS=Homo sapiens OX=9606 GN=NT5E","NT5E",63.367,26.931,6.6,4,4,4,1.069,1.01,1.054,0.914,0.955,1.009,0.919,0.0623,"peroxisome\r","GO:0042278 purine nucleoside metabolic process; GO:0046135 pyrimidine nucleoside catabolic process; GO:0009116 nucleoside metabolic process; GO:0019362 pyridine nucleotide metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0006196 AMP catabolic process; GO:0044699 single-organism process; GO:0009163 nucleoside biosynthetic process; GO:0046129 purine ribonucleoside biosynthetic process; GO:0009058 biosynthetic process; GO:0031347 regulation of defense response; GO:0072524 pyridine-containing compound metabolic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0022610 biological adhesion; GO:0016337 single organismal cell-cell adhesion; GO:0008152 metabolic process; GO:1901292 nucleoside phosphate catabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0006213 pyrimidine nucleoside metabolic process; GO:0006195 purine nucleotide catabolic process; GO:0046130 purine ribonucleoside catabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0032102 negative regulation of response to external stimulus; GO:0019693 ribose phosphate metabolic process; GO:0007155 cell adhesion; GO:1901361 organic cyclic compound catabolic process; GO:0072527 pyrimidine-containing compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0018130 heterocycle biosynthetic process; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0009125 nucleoside monophosphate catabolic process; GO:0009158 ribonucleoside monophosphate catabolic process; GO:0009166 nucleotide catabolic process; GO:0044281 small molecule metabolic process; GO:0098609 cell-cell adhesion; GO:0044763 single-organism cellular process; GO:0072521 purine-containing compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0006732 coenzyme metabolic process; GO:0009154 purine ribonucleotide catabolic process; GO:0051186 cofactor metabolic process; GO:0042451 purine nucleoside biosynthetic process; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0072529 pyrimidine-containing compound catabolic process; GO:0006152 purine nucleoside catabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0019674 NAD metabolic process; GO:0072522 purine-containing compound biosynthetic process; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0098602 single organism cell adhesion; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0007159 leukocyte cell-cell adhesion; GO:0006725 cellular aromatic compound metabolic process; GO:0046496 nicotinamide nucleotide metabolic process; GO:0046434 organophosphate catabolic process; GO:0009259 ribonucleotide metabolic process; GO:0006259 DNA metabolic process; GO:0050728 negative regulation of inflammatory response; GO:0009169 purine ribonucleoside monophosphate catabolic process; GO:0072523 purine-containing compound catabolic process; GO:0080134 regulation of response to stress; GO:0048519 negative regulation of biological process; GO:0046033 AMP metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0042454 ribonucleoside catabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0009128 purine nucleoside monophosphate catabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:1901135 carbohydrate derivative metabolic process; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0009119 ribonucleoside metabolic process; GO:0031348 negative regulation of defense response; GO:0044711 single-organism biosynthetic process; GO:0046086 adenosine biosynthetic process; GO:0044712 single-organism catabolic process; GO:1901658 glycosyl compound catabolic process; GO:0046085 adenosine metabolic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:1901136 carbohydrate derivative catabolic process; GO:0032101 regulation of response to external stimulus; GO:0048585 negative regulation of response to stimulus; GO:0044238 primary metabolic process; GO:0042455 ribonucleoside biosynthetic process; GO:0016311 dephosphorylation; GO:0009261 ribonucleotide catabolic process; GO:1901576 organic substance biosynthetic process; GO:0006163 purine nucleotide metabolic process; GO:0044249 cellular biosynthetic process; GO:0046128 purine ribonucleoside metabolic process; GO:1901565 organonitrogen compound catabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006793 phosphorus metabolic process; GO:1901659 glycosyl compound biosynthetic process; GO:0050727 regulation of inflammatory response; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0009164 nucleoside catabolic process; GO:0009056 catabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:0065007 biological regulation; GO:1901564 organonitrogen compound metabolic process; GO:0046700 heterocycle catabolic process; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0031225 anchored component of membrane; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0009986 cell surface; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0016791 phosphatase activity; GO:0008252 nucleotidase activity; GO:0043167 ion binding; GO:0016787 hydrolase activity; GO:0000166 nucleotide binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0008253 5'-nucleotidase activity; GO:0003824 catalytic activity; GO:0042578 phosphoric ester hydrolase activity; GO:0005488 binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0036094 small molecule binding; ","K19970","NT5E; 5'-nucleotidase [EC:3.1.3.5]","hsa00760 Nicotinate and nicotinamide metabolism - Homo sapiens (human); hsa00230 Purine metabolism - Homo sapiens (human); hsa00240 Pyrimidine metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR029052; IPR004843; IPR008334; ","\"Metallo-dependent phosphatase-like; Calcineurin-like phosphoesterase domain, ApaH type; 5'-Nucleotidase, C-terminal; \"\r"]
["P21695","Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic OS=Homo sapiens OX=9606 GN=GPD1","GPD1",37.567,54.54,43.3,15,22,15,1.202,1.203,1.289,0.766,0.781,0.769,0.627,4.03e-05,"cytoplasm\r","GO:0019362 pyridine nucleotide metabolic process; GO:0046683 response to organophosphorus; GO:0044255 cellular lipid metabolic process; GO:0051194 positive regulation of cofactor metabolic process; GO:0071345 cellular response to cytokine stimulus; GO:0044237 cellular metabolic process; GO:0019432 triglyceride biosynthetic process; GO:0008610 lipid biosynthetic process; GO:0006006 glucose metabolic process; GO:0008152 metabolic process; GO:0006094 gluconeogenesis; GO:0006091 generation of precursor metabolites and energy; GO:0042180 cellular ketone metabolic process; GO:0006639 acylglycerol metabolic process; GO:0009719 response to endogenous stimulus; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0042325 regulation of phosphorylation; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:0006116 NADH oxidation; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006072 glycerol-3-phosphate metabolic process; GO:0006732 coenzyme metabolic process; GO:0046473 phosphatidic acid metabolic process; GO:0005975 carbohydrate metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0090407 organophosphate biosynthetic process; GO:1901575 organic substance catabolic process; GO:0006127 glycerophosphate shuttle; GO:0010243 response to organonitrogen compound; GO:0051591 response to cAMP; GO:0019674 NAD metabolic process; GO:0044710 single-organism metabolic process; GO:1901698 response to nitrogen compound; GO:0022900 electron transport chain; GO:0045981 positive regulation of nucleotide metabolic process; GO:0006140 regulation of nucleotide metabolic process; GO:0050794 regulation of cellular process; GO:0046496 nicotinamide nucleotide metabolic process; GO:0045821 positive regulation of glycolytic process; GO:1901700 response to oxygen-containing compound; GO:0046364 monosaccharide biosynthetic process; GO:0046168 glycerol-3-phosphate catabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0014074 response to purine-containing compound; GO:0009896 positive regulation of catabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0006638 neutral lipid metabolic process; GO:0044711 single-organism biosynthetic process; GO:1901136 carbohydrate derivative catabolic process; GO:0071407 cellular response to organic cyclic compound; GO:0010033 response to organic substance; GO:0006109 regulation of carbohydrate metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0006641 triglyceride metabolic process; GO:0006793 phosphorus metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0044283 small molecule biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0006644 phospholipid metabolic process; GO:0019318 hexose metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0045913 positive regulation of carbohydrate metabolic process; GO:0043467 regulation of generation of precursor metabolites and energy; GO:0046486 glycerolipid metabolic process; GO:0019319 hexose biosynthetic process; GO:0009117 nucleotide metabolic process; GO:0006654 phosphatidic acid biosynthetic process; GO:0031331 positive regulation of cellular catabolic process; GO:0008654 phospholipid biosynthetic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0072524 pyridine-containing compound metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051196 regulation of coenzyme metabolic process; GO:0046460 neutral lipid biosynthetic process; GO:0009893 positive regulation of metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0006650 glycerophospholipid metabolic process; GO:0034612 response to tumor necrosis factor; GO:0070887 cellular response to chemical stimulus; GO:0006629 lipid metabolic process; GO:0051193 regulation of cofactor metabolic process; GO:0045937 positive regulation of phosphate metabolic process; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0034097 response to cytokine; GO:0055114 oxidation-reduction process; GO:0006110 regulation of glycolytic process; GO:0043470 regulation of carbohydrate catabolic process; GO:0052646 alditol phosphate metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0051186 cofactor metabolic process; GO:0071417 cellular response to organonitrogen compound; GO:0044723 single-organism carbohydrate metabolic process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:1901699 cellular response to nitrogen compound; GO:0015980 energy derivation by oxidation of organic compounds; GO:0046474 glycerophospholipid biosynthetic process; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0016051 carbohydrate biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0046434 organophosphate catabolic process; GO:0071356 cellular response to tumor necrosis factor; GO:0051197 positive regulation of coenzyme metabolic process; GO:0006734 NADH metabolic process; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0009118 regulation of nucleoside metabolic process; GO:0046463 acylglycerol biosynthetic process; GO:0022904 respiratory electron transport chain; GO:1900544 positive regulation of purine nucleotide metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0005996 monosaccharide metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:1903578 regulation of ATP metabolic process; GO:0071320 cellular response to cAMP; GO:0006807 nitrogen compound metabolic process; GO:0045333 cellular respiration; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0045017 glycerolipid biosynthetic process; GO:1900542 regulation of purine nucleotide metabolic process; GO:0045979 positive regulation of nucleoside metabolic process; GO:1901701 cellular response to oxygen-containing compound; GO:0071495 cellular response to endogenous stimulus; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0009056 catabolic process; GO:1903580 positive regulation of ATP metabolic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:1902494 catalytic complex; GO:0005622 intracellular; GO:0044464 cell part; GO:1990204 oxidoreductase complex; GO:1903561 extracellular vesicle; GO:0009331 glycerol-3-phosphate dehydrogenase complex; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0048037 cofactor binding; GO:0004368 glycerol-3-phosphate dehydrogenase activity; GO:0016491 oxidoreductase activity; GO:0016614 oxidoreductase activity, acting on CH-OH group of donors; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor; GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0051287 NAD binding; GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0050662 coenzyme binding; GO:0036094 small molecule binding; ","K00006","GPD1; glycerol-3-phosphate dehydrogenase (NAD+) [EC:1.1.1.8]","hsa00564 Glycerophospholipid metabolism - Homo sapiens (human); ","IPR008927; IPR013328; IPR016040; IPR006109; IPR011128; ","\"6-phosphogluconate dehydrogenase C-terminal domain-like; 6-phosphogluconate dehydrogenase, domain 2; NAD(P)-binding domain; Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal; Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal; \"\r"]
["P21796","Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1","VDAC1",30.772,107.18,54.1,13,33,13,0.893,0.885,1.03,1.08,1.063,1.044,1.135,0.0617,"cytoplasm\r","GO:0044700 single organism signaling; GO:0048869 cellular developmental process; GO:0006839 mitochondrial transport; GO:0044070 regulation of anion transport; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0006914 autophagy; GO:0010821 regulation of mitochondrion organization; GO:0044237 cellular metabolic process; GO:0050877 neurological system process; GO:0007270 neuron-neuron synaptic transmission; GO:0051234 establishment of localization; GO:0007610 behavior; GO:0008152 metabolic process; GO:0007154 cell communication; GO:0032879 regulation of localization; GO:0006915 apoptotic process; GO:0098916 anterograde trans-synaptic signaling; GO:0044419 interspecies interaction between organisms; GO:0016236 macroautophagy; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0009888 tissue development; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0043269 regulation of ion transport; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0031323 regulation of cellular metabolic process; GO:0023052 signaling; GO:0010506 regulation of autophagy; GO:0032501 multicellular organismal process; GO:1903959 regulation of anion transmembrane transport; GO:0051704 multi-organism process; GO:0006851 mitochondrial calcium ion transport; GO:0034762 regulation of transmembrane transport; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0007267 cell-cell signaling; GO:0007612 learning; GO:0019222 regulation of metabolic process; GO:0006952 defense response; GO:0048856 anatomical structure development; GO:2000377 regulation of reactive oxygen species metabolic process; GO:0044708 single-organism behavior; GO:0030855 epithelial cell differentiation; GO:0042596 fear response; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0072511 divalent inorganic cation transport; GO:0034220 ion transmembrane transport; GO:0030001 metal ion transport; GO:0033555 multicellular organismal response to stress; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0098656 anion transmembrane transport; GO:0030154 cell differentiation; GO:0006812 cation transport; GO:0006816 calcium ion transport; GO:0016032 viral process; GO:0001662 behavioral fear response; GO:0050890 cognition; GO:0099537 trans-synaptic signaling; GO:0002209 behavioral defense response; GO:0044248 cellular catabolic process; GO:2000378 negative regulation of reactive oxygen species metabolic process; GO:0009987 cellular process; GO:0003008 system process; GO:0006950 response to stress; GO:0051049 regulation of transport; GO:0033043 regulation of organelle organization; GO:0009892 negative regulation of metabolic process; GO:0007611 learning or memory; GO:0006820 anion transport; GO:0055085 transmembrane transport; GO:0099536 synaptic signaling; GO:0034765 regulation of ion transmembrane transport; GO:1903146 regulation of mitophagy; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0006811 ion transport; GO:0051128 regulation of cellular component organization; GO:0012501 programmed cell death; GO:0007268 chemical synaptic transmission; GO:0051179 localization; GO:0009056 catabolic process; GO:0070838 divalent metal ion transport; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0019867 outer membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0098857 membrane microdomain; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070382 exocytic vesicle; GO:0070062 extracellular exosome; GO:0008021 synaptic vesicle; GO:0043209 myelin sheath; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0098589 membrane region; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0097458 neuron part; GO:0043233 organelle lumen; GO:0005759 mitochondrial matrix; GO:0042645 mitochondrial nucleoid; GO:0031967 organelle envelope; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0031975 envelope; GO:0043234 protein complex; GO:0030133 transport vesicle; GO:0009295 nucleoid; GO:0031966 mitochondrial membrane; GO:0043230 extracellular organelle; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0098793 presynapse; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0019866 organelle inner membrane; GO:0031968 organelle outer membrane; GO:0045121 membrane raft; GO:0044456 synapse part; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005741 mitochondrial outer membrane; GO:0046930 pore complex; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0016021 integral component of membrane; GO:0045202 synapse; GO:0043226 organelle; GO:0005634 nucleus; GO:0044444 cytoplasmic part; ","GO:0015075 ion transmembrane transporter activity; GO:0044877 macromolecular complex binding; GO:0022803 passive transmembrane transporter activity; GO:0019901 protein kinase binding; GO:0005253 anion channel activity; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0019900 kinase binding; GO:0015267 channel activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0005244 voltage-gated ion channel activity; GO:0008308 voltage-gated anion channel activity; GO:0022829 wide pore channel activity; GO:0022838 substrate-specific channel activity; GO:0005488 binding; GO:0044325 ion channel binding; GO:0015288 porin activity; GO:0022836 gated channel activity; GO:0005216 ion channel activity; GO:0022832 voltage-gated channel activity; GO:0019899 enzyme binding; GO:0032403 protein complex binding; GO:0008509 anion transmembrane transporter activity; GO:0022857 transmembrane transporter activity; GO:0005215 transporter activity; ","K05862","VDAC1; voltage-dependent anion channel protein 1","hsa04218 Cellular senescence - Homo sapiens (human); hsa04979 Cholesterol metabolism - Homo sapiens (human); hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human); hsa04217 Necroptosis - Homo sapiens (human); hsa04020 Calcium signaling pathway - Homo sapiens (human); hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human); hsa05166 HTLV-I infection - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa05164 Influenza A - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); ","IPR023614; ","Porin domain; \r"]
["P21810","Biglycan OS=Homo sapiens OX=9606 GN=BGN","BGN",41.654,224.11,38.3,11,45,10,0.983,1.025,0.976,1.026,1.016,0.986,1.015,0.49,"mitochondria\r","GO:0044700 single organism signaling; GO:0007166 cell surface receptor signaling pathway; GO:0071345 cellular response to cytokine stimulus; GO:0044237 cellular metabolic process; GO:0044272 sulfur compound biosynthetic process; GO:0030203 glycosaminoglycan metabolic process; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0032787 monocarboxylic acid metabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0006790 sulfur compound metabolic process; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0030205 dermatan sulfate metabolic process; GO:0009100 glycoprotein metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0043086 negative regulation of catalytic activity; GO:0032501 multicellular organismal process; GO:0006027 glycosaminoglycan catabolic process; GO:1901575 organic substance catabolic process; GO:1902532 negative regulation of intracellular signal transduction; GO:0006029 proteoglycan metabolic process; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0043436 oxoacid metabolic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0018149 peptide cross-linking; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0023057 negative regulation of signaling; GO:0030208 dermatan sulfate biosynthetic process; GO:0010648 negative regulation of cell communication; GO:0046426 negative regulation of JAK-STAT cascade; GO:0043062 extracellular structure organization; GO:0051338 regulation of transferase activity; GO:0001974 blood vessel remodeling; GO:1901135 carbohydrate derivative metabolic process; GO:0044248 cellular catabolic process; GO:0001933 negative regulation of protein phosphorylation; GO:0009966 regulation of signal transduction; GO:1904892 regulation of STAT cascade; GO:0006023 aminoglycan biosynthetic process; GO:1902531 regulation of intracellular signal transduction; GO:0044711 single-organism biosynthetic process; GO:1901136 carbohydrate derivative catabolic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044283 small molecule biosynthetic process; GO:0050650 chondroitin sulfate proteoglycan biosynthetic process; GO:0043412 macromolecule modification; GO:0072330 monocarboxylic acid biosynthetic process; GO:0045936 negative regulation of phosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0030206 chondroitin sulfate biosynthetic process; GO:0009968 negative regulation of signal transduction; GO:0016053 organic acid biosynthetic process; GO:0006024 glycosaminoglycan biosynthetic process; GO:0018209 peptidyl-serine modification; GO:0006026 aminoglycan catabolic process; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0030207 chondroitin sulfate catabolic process; GO:0031400 negative regulation of protein modification process; GO:0030204 chondroitin sulfate metabolic process; GO:0030166 proteoglycan biosynthetic process; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0033673 negative regulation of kinase activity; GO:0030198 extracellular matrix organization; GO:0070887 cellular response to chemical stimulus; GO:0009101 glycoprotein biosynthetic process; GO:0034097 response to cytokine; GO:0051348 negative regulation of transferase activity; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0046394 carboxylic acid biosynthetic process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0006469 negative regulation of protein kinase activity; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0044273 sulfur compound catabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0006082 organic acid metabolic process; GO:0036211 protein modification process; GO:0043549 regulation of kinase activity; GO:0046425 regulation of JAK-STAT cascade; GO:0045859 regulation of protein kinase activity; GO:0016043 cellular component organization; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:1901566 organonitrogen compound biosynthetic process; GO:0050651 dermatan sulfate proteoglycan biosynthetic process; GO:0071704 organic substance metabolic process; GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan; GO:1904893 negative regulation of STAT cascade; GO:0050654 chondroitin sulfate proteoglycan metabolic process; GO:0042326 negative regulation of phosphorylation; GO:0009059 macromolecule biosynthetic process; GO:0050655 dermatan sulfate proteoglycan metabolic process; GO:0019221 cytokine-mediated signaling pathway; GO:0006022 aminoglycan metabolic process; GO:0009987 cellular process; GO:0048771 tissue remodeling; GO:1903510 mucopolysaccharide metabolic process; GO:0044712 single-organism catabolic process; GO:0001932 regulation of protein phosphorylation; GO:0006807 nitrogen compound metabolic process; GO:0048585 negative regulation of response to stimulus; GO:0044249 cellular biosynthetic process; GO:0018193 peptidyl-amino acid modification; GO:1901565 organonitrogen compound catabolic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0051246 regulation of protein metabolic process; GO:0009057 macromolecule catabolic process; GO:0010563 negative regulation of phosphorus metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0009056 catabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0005796 Golgi lumen; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0043202 lysosomal lumen; GO:0005886 plasma membrane; GO:0031012 extracellular matrix; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044437 vacuolar part; GO:0005578 proteinaceous extracellular matrix; GO:0005773 vacuole; GO:0009986 cell surface; GO:0030133 transport vesicle; GO:0005794 Golgi apparatus; GO:0042383 sarcolemma; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005201 extracellular matrix structural constituent; GO:0097367 carbohydrate derivative binding; GO:0030234 enzyme regulator activity; GO:0019210 kinase inhibitor activity; GO:0005488 binding; GO:0005515 protein binding; GO:0004860 protein kinase inhibitor activity; GO:0019207 kinase regulator activity; GO:0019887 protein kinase regulator activity; GO:0005539 glycosaminoglycan binding; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0005198 structural molecule activity; GO:0050840 extracellular matrix binding; ","K08118",null,null,"IPR000372; IPR032675; ","\"Leucine-rich repeat N-terminal domain; Leucine-rich repeat domain, L domain-like; \"\r"]
["P21912","Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHB","SDHB",31.629,32.36,30.7,8,10,8,0.902,0.904,1.089,1.04,1.043,0.996,1.064,0.366,"mitochondria\r","GO:0072350 tricarboxylic acid metabolic process; GO:0043648 dicarboxylic acid metabolic process; GO:0006105 succinate metabolic process; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0006099 tricarboxylic acid cycle; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0022904 respiratory electron transport chain; GO:0044238 primary metabolic process; GO:0045333 cellular respiration; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0006101 citrate metabolic process; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0009060 aerobic respiration; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0019752 carboxylic acid metabolic process; GO:0022900 electron transport chain; GO:0006082 organic acid metabolic process; GO:0009987 cellular process; GO:0043436 oxoacid metabolic process; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0045281 succinate dehydrogenase complex; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044455 mitochondrial membrane part; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0005740 mitochondrial envelope; GO:0005654 nucleoplasm; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0045283 fumarate reductase complex; GO:1903561 extracellular vesicle; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0098803 respiratory chain complex; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0045257 succinate dehydrogenase complex (ubiquinone); GO:0031981 nuclear lumen; GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone); GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0005746 mitochondrial respiratory chain; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:1990204 oxidoreductase complex; GO:0031975 envelope; GO:0045273 respiratory chain complex II; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0070469 respiratory chain; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0051537 2 iron, 2 sulfur cluster binding; GO:0043167 ion binding; GO:0000104 succinate dehydrogenase activity; GO:0005515 protein binding; GO:0051539 4 iron, 4 sulfur cluster binding; GO:0048037 cofactor binding; GO:0016491 oxidoreductase activity; GO:0051538 3 iron, 4 sulfur cluster binding; GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors; GO:0009055 electron carrier activity; GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor; GO:0003824 catalytic activity; GO:0051536 iron-sulfur cluster binding; GO:0005488 binding; GO:0048039 ubiquinone binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0008177 succinate dehydrogenase (ubiquinone) activity; GO:0048038 quinone binding; GO:0051540 metal cluster binding; ","K00235","SDHB; succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1]","hsa05010 Alzheimer's disease - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00020 Citrate cycle (TCA cycle) - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); ","IPR001041; IPR017896; IPR009051; IPR012675; IPR025192; ","\"2Fe-2S ferredoxin-type iron-sulfur binding domain; 4Fe-4S ferredoxin-type, iron-sulphur binding domain; Alpha-helical ferredoxin; Beta-grasp domain; Succinate dehydogenase/fumarate reductase N-terminal; \"\r"]
["P21926","CD9 antigen OS=Homo sapiens OX=9606 GN=CD9","CD9",25.416,17.475,15.8,6,14,6,1.107,1.073,1,0.917,1.009,0.908,0.891,0.0627,"plasma membrane\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0007596 blood coagulation; GO:0001101 response to acid chemical; GO:0031623 receptor internalization; GO:0007272 ensheathment of neurons; GO:0022414 reproductive process; GO:0007166 cell surface receptor signaling pathway; GO:0007420 brain development; GO:0048869 cellular developmental process; GO:0045216 cell-cell junction organization; GO:0032989 cellular component morphogenesis; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0014003 oligodendrocyte development; GO:0044237 cellular metabolic process; GO:0008285 negative regulation of cell proliferation; GO:0051234 establishment of localization; GO:0009611 response to wounding; GO:0022610 biological adhesion; GO:0055098 response to low-density lipoprotein particle; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0007342 fusion of sperm to egg plasma membrane; GO:0048709 oligodendrocyte differentiation; GO:0007154 cell communication; GO:0009415 response to water; GO:0022607 cellular component assembly; GO:0044702 single organism reproductive process; GO:0007155 cell adhesion; GO:0009719 response to endogenous stimulus; GO:0060322 head development; GO:0055094 response to lipoprotein particle; GO:0043170 macromolecule metabolic process; GO:0010035 response to inorganic substance; GO:0044801 single-organism membrane fusion; GO:0070887 cellular response to chemical stimulus; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0009414 response to water deprivation; GO:0071402 cellular response to lipoprotein particle stimulus; GO:0043112 receptor metabolic process; GO:0030168 platelet activation; GO:0019953 sexual reproduction; GO:0044763 single-organism cellular process; GO:0061025 membrane fusion; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0042552 myelination; GO:0006810 transport; GO:0009566 fertilization; GO:0048513 animal organ development; GO:0042063 gliogenesis; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0032940 secretion by cell; GO:0007417 central nervous system development; GO:0044710 single-organism metabolic process; GO:0022412 cellular process involved in reproduction in multicellular organism; GO:0021782 glial cell development; GO:0044260 cellular macromolecule metabolic process; GO:0045026 plasma membrane fusion; GO:0050817 coagulation; GO:0048856 anatomical structure development; GO:0030913 paranodal junction assembly; GO:0000003 reproduction; GO:0050794 regulation of cellular process; GO:0034329 cell junction assembly; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0042127 regulation of cell proliferation; GO:0009628 response to abiotic stimulus; GO:0008366 axon ensheathment; GO:0071310 cellular response to organic substance; GO:1901700 response to oxygen-containing compound; GO:0002576 platelet degranulation; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0007599 hemostasis; GO:0071704 organic substance metabolic process; GO:0009653 anatomical structure morphogenesis; GO:0030154 cell differentiation; GO:1902578 single-organism localization; GO:0032288 myelin assembly; GO:0007275 multicellular organism development; GO:0006898 receptor-mediated endocytosis; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0009987 cellular process; GO:0007043 cell-cell junction assembly; GO:0071404 cellular response to low-density lipoprotein particle stimulus; GO:0050878 regulation of body fluid levels; GO:0006950 response to stress; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0010927 cellular component assembly involved in morphogenesis; GO:0044802 single-organism membrane organization; GO:0010033 response to organic substance; GO:0007338 single fertilization; GO:0006897 endocytosis; GO:0032504 multicellular organism reproduction; GO:0010001 glial cell differentiation; GO:0045055 regulated exocytosis; GO:0034330 cell junction organization; GO:0042060 wound healing; GO:0071495 cellular response to endogenous stimulus; GO:0044767 single-organism developmental process; GO:0061024 membrane organization; GO:0044703 multi-organism reproductive process; GO:0006928 movement of cell or subcellular component; GO:0001775 cell activation; GO:0051179 localization; GO:0071840 cellular component organization or biogenesis; GO:0006887 exocytosis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0009897 external side of plasma membrane; GO:0016324 apical plasma membrane; GO:0045334 clathrin-coated endocytic vesicle; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0030669 clathrin-coated endocytic vesicle membrane; GO:0044433 cytoplasmic vesicle part; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0030662 coated vesicle membrane; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0098590 plasma membrane region; GO:0030136 clathrin-coated vesicle; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0099503 secretory vesicle; GO:0098805 whole membrane; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0030055 cell-substrate junction; GO:0030139 endocytic vesicle; GO:0043227 membrane-bounded organelle; GO:0045177 apical part of cell; GO:0005924 cell-substrate adherens junction; GO:0031092 platelet alpha granule membrane; GO:0098552 side of membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0031226 intrinsic component of plasma membrane; GO:0098588 bounding membrane of organelle; GO:0030666 endocytic vesicle membrane; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0016021 integral component of membrane; GO:0030665 clathrin-coated vesicle membrane; GO:0030135 coated vesicle; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0030667 secretory granule membrane; GO:0044459 plasma membrane part; GO:0009986 cell surface; GO:0031091 platelet alpha granule; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0050839 cell adhesion molecule binding; GO:0005102 receptor binding; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0005515 protein binding; GO:0005178 integrin binding; GO:0032403 protein complex binding; ","K06460","CD9; CD9 antigen","hsa04640 Hematopoietic cell lineage - Homo sapiens (human); ","IPR028977; IPR008952; ","\"CD81 antigen, large extracellular loop domain; Tetraspanin, EC2 domain; \"\r"]
["P21964","Catechol O-methyltransferase OS=Homo sapiens OX=9606 GN=COMT","COMT",30.037,118.58,57.2,13,26,13,1.044,1.021,1.043,0.952,0.958,0.968,0.926,0.000922,"extracellular\r","GO:0065008 regulation of biological quality; GO:0031335 regulation of sulfur amino acid metabolic process; GO:0022414 reproductive process; GO:0035813 regulation of renal sodium excretion; GO:0045914 negative regulation of catecholamine metabolic process; GO:0044237 cellular metabolic process; GO:0050877 neurological system process; GO:0008285 negative regulation of cell proliferation; GO:0009607 response to biotic stimulus; GO:0007610 behavior; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0032879 regulation of localization; GO:0044706 multi-multicellular organism process; GO:0042424 catecholamine catabolic process; GO:0044057 regulation of system process; GO:0008210 estrogen metabolic process; GO:0050668 positive regulation of homocysteine metabolic process; GO:0051051 negative regulation of transport; GO:0051716 cellular response to stimulus; GO:0014070 response to organic cyclic compound; GO:0042069 regulation of catecholamine metabolic process; GO:0006521 regulation of cellular amino acid metabolic process; GO:0080090 regulation of primary metabolic process; GO:0008202 steroid metabolic process; GO:0044763 single-organism cellular process; GO:0009712 catechol-containing compound metabolic process; GO:0048265 response to pain; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0034754 cellular hormone metabolic process; GO:0019439 aromatic compound catabolic process; GO:1901575 organic substance catabolic process; GO:0007612 learning; GO:0018958 phenol-containing compound metabolic process; GO:0044710 single-organism metabolic process; GO:0010817 regulation of hormone levels; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0048609 multicellular organismal reproductive process; GO:0044708 single-organism behavior; GO:0050666 regulation of homocysteine metabolic process; GO:0000003 reproduction; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0044707 single-multicellular organism process; GO:0009267 cellular response to starvation; GO:0042127 regulation of cell proliferation; GO:1901615 organic hydroxy compound metabolic process; GO:0019614 catechol-containing compound catabolic process; GO:1901700 response to oxygen-containing compound; GO:0097164 ammonium ion metabolic process; GO:0033555 multicellular organismal response to stress; GO:0048523 negative regulation of cellular process; GO:0042135 neurotransmitter catabolic process; GO:0048519 negative regulation of biological process; GO:0032844 regulation of homeostatic process; GO:0051239 regulation of multicellular organismal process; GO:0007565 female pregnancy; GO:0042493 response to drug; GO:0051176 positive regulation of sulfur metabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0044248 cellular catabolic process; GO:0051930 regulation of sensory perception of pain; GO:0009617 response to bacterium; GO:0006950 response to stress; GO:0032496 response to lipopolysaccharide; GO:0071496 cellular response to external stimulus; GO:0044062 regulation of excretion; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0031668 cellular response to extracellular stimulus; GO:0016036 cellular response to phosphate starvation; GO:0031325 positive regulation of cellular metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0001505 regulation of neurotransmitter levels; GO:0042053 regulation of dopamine metabolic process; GO:0051241 negative regulation of multicellular organismal process; GO:0051046 regulation of secretion; GO:0044699 single-organism process; GO:0031337 positive regulation of sulfur amino acid metabolic process; GO:0032259 methylation; GO:0033239 negative regulation of cellular amine metabolic process; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0031644 regulation of neurological system process; GO:1901361 organic cyclic compound catabolic process; GO:0006629 lipid metabolic process; GO:0032502 developmental process; GO:0042445 hormone metabolic process; GO:0098801 regulation of renal system process; GO:0045764 positive regulation of cellular amino acid metabolic process; GO:0002237 response to molecule of bacterial origin; GO:0033240 positive regulation of cellular amine metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0006584 catecholamine metabolic process; GO:0010565 regulation of cellular ketone metabolic process; GO:0051048 negative regulation of secretion; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0019222 regulation of metabolic process; GO:0007613 memory; GO:0019336 phenol-containing compound catabolic process; GO:0042762 regulation of sulfur metabolic process; GO:2000021 regulation of ion homeostasis; GO:0006725 cellular aromatic compound metabolic process; GO:0048660 regulation of smooth muscle cell proliferation; GO:0031324 negative regulation of cellular metabolic process; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0031669 cellular response to nutrient levels; GO:0071704 organic substance metabolic process; GO:0033993 response to lipid; GO:0009991 response to extracellular stimulus; GO:0035814 negative regulation of renal sodium excretion; GO:1901616 organic hydroxy compound catabolic process; GO:0042133 neurotransmitter metabolic process; GO:0050890 cognition; GO:0009987 cellular process; GO:0033238 regulation of cellular amine metabolic process; GO:0003008 system process; GO:0051931 regulation of sensory perception; GO:0051049 regulation of transport; GO:0042420 dopamine catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0032845 negative regulation of homeostatic process; GO:0042417 dopamine metabolic process; GO:0048518 positive regulation of biological process; GO:0007614 short-term memory; GO:0007611 learning or memory; GO:0032504 multicellular organism reproduction; GO:0048662 negative regulation of smooth muscle cell proliferation; GO:1901565 organonitrogen compound catabolic process; GO:0044703 multi-organism reproductive process; GO:0042594 response to starvation; GO:0045963 negative regulation of dopamine metabolic process; GO:0031667 response to nutrient levels; GO:0009056 catabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0030425 dendrite; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0043197 dendritic spine; GO:0070062 extracellular exosome; GO:0098590 plasma membrane region; GO:0044309 neuron spine; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0097060 synaptic membrane; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0044456 synapse part; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0044463 cell projection part; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0045202 synapse; GO:0045211 postsynaptic membrane; GO:0030424 axon; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0044459 plasma membrane part; GO:0098794 postsynapse; GO:0044297 cell body; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0000287 magnesium ion binding; GO:0008757 S-adenosylmethionine-dependent methyltransferase activity; GO:0008168 methyltransferase activity; GO:0016206 catechol O-methyltransferase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0016741 transferase activity, transferring one-carbon groups; GO:0008171 O-methyltransferase activity; GO:0005515 protein binding; GO:0016740 transferase activity; GO:0102084 L-dopa O-methyltransferase activity; ","K00545","COMT; catechol O-methyltransferase [EC:2.1.1.6]","hsa00140 Steroid hormone biosynthesis - Homo sapiens (human); hsa04728 Dopaminergic synapse - Homo sapiens (human); hsa00350 Tyrosine metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR029063; ","S-adenosyl-L-methionine-dependent methyltransferase; \r"]
["P21980","Protein-glutamine gamma-glutamyltransferase 2 OS=Homo sapiens OX=9606 GN=TGM2","TGM2",77.328,21.997,11.8,7,8,7,0.928,0.968,0.881,1.073,0.989,1.167,1.163,0.0533,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0065008 regulation of biological quality; GO:0048732 gland development; GO:0035148 tube formation; GO:0031347 regulation of defense response; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0065003 macromolecular complex assembly; GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling; GO:0055065 metal ion homeostasis; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044765 single-organism transport; GO:0060445 branching involved in salivary gland morphogenesis; GO:0051716 cellular response to stimulus; GO:0050729 positive regulation of inflammatory response; GO:0060605 tube lumen cavitation; GO:0051561 positive regulation of mitochondrial calcium ion concentration; GO:0001763 morphogenesis of a branching structure; GO:0035239 tube morphogenesis; GO:0044763 single-organism cellular process; GO:0032501 multicellular organismal process; GO:0006874 cellular calcium ion homeostasis; GO:0006810 transport; GO:0048513 animal organ development; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0009887 animal organ morphogenesis; GO:0006464 cellular protein modification process; GO:0043068 positive regulation of programmed cell death; GO:0050794 regulation of cellular process; GO:0002009 morphogenesis of an epithelium; GO:0044707 single-multicellular organism process; GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway; GO:0042127 regulation of cell proliferation; GO:0051260 protein homooligomerization; GO:0044267 cellular protein metabolic process; GO:0018149 peptide cross-linking; GO:0043067 regulation of programmed cell death; GO:0080134 regulation of response to stress; GO:0051259 protein oligomerization; GO:0009653 anatomical structure morphogenesis; GO:0031349 positive regulation of defense response; GO:1902578 single-organism localization; GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration; GO:0001974 blood vessel remodeling; GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0048878 chemical homeostasis; GO:0006461 protein complex assembly; GO:1902531 regulation of intracellular signal transduction; GO:0018199 peptidyl-glutamine modification; GO:0045785 positive regulation of cell adhesion; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0051560 mitochondrial calcium ion homeostasis; GO:0032101 regulation of response to external stimulus; GO:0044238 primary metabolic process; GO:0030155 regulation of cell adhesion; GO:0007186 G-protein coupled receptor signaling pathway; GO:0061138 morphogenesis of a branching epithelium; GO:0006873 cellular ion homeostasis; GO:0048661 positive regulation of smooth muscle cell proliferation; GO:0032469 endoplasmic reticulum calcium ion homeostasis; GO:0007435 salivary gland morphogenesis; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0007204 positive regulation of cytosolic calcium ion concentration; GO:0043412 macromolecule modification; GO:0008284 positive regulation of cell proliferation; GO:0072503 cellular divalent inorganic cation homeostasis; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0060662 salivary gland cavitation; GO:0051234 establishment of localization; GO:0006909 phagocytosis; GO:0007165 signal transduction; GO:0048729 tissue morphogenesis; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0032103 positive regulation of response to external stimulus; GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway; GO:0032502 developmental process; GO:0035295 tube development; GO:0060429 epithelium development; GO:0071822 protein complex subunit organization; GO:0009888 tissue development; GO:0050801 ion homeostasis; GO:0055074 calcium ion homeostasis; GO:0098771 inorganic ion homeostasis; GO:0019725 cellular homeostasis; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0010942 positive regulation of cell death; GO:0050789 regulation of biological process; GO:0018262 isopeptide cross-linking; GO:0070271 protein complex biogenesis; GO:0036211 protein modification process; GO:0072507 divalent inorganic cation homeostasis; GO:0048856 anatomical structure development; GO:0016043 cellular component organization; GO:0048660 regulation of smooth muscle cell proliferation; GO:0030003 cellular cation homeostasis; GO:0051480 regulation of cytosolic calcium ion concentration; GO:0043065 positive regulation of apoptotic process; GO:0007431 salivary gland development; GO:0050896 response to stimulus; GO:0055082 cellular chemical homeostasis; GO:0071704 organic substance metabolic process; GO:0018205 peptidyl-lysine modification; GO:0042592 homeostatic process; GO:0055080 cation homeostasis; GO:0043277 apoptotic cell clearance; GO:0023056 positive regulation of signaling; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:0048771 tissue remodeling; GO:0035272 exocrine system development; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0043933 macromolecular complex subunit organization; GO:0018193 peptidyl-amino acid modification; GO:0044767 single-organism developmental process; GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling; GO:0050727 regulation of inflammatory response; GO:0006875 cellular metal ion homeostasis; GO:0009967 positive regulation of signal transduction; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:0022612 gland morphogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043229 intracellular organelle; GO:0031226 intrinsic component of plasma membrane; GO:0070161 anchoring junction; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0031012 extracellular matrix; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044459 plasma membrane part; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0016755 transferase activity, transferring amino-acyl groups; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0016746 transferase activity, transferring acyl groups; GO:0097367 carbohydrate derivative binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0019904 protein domain specific binding; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0016740 transferase activity; GO:0003810 protein-glutamine gamma-glutamyltransferase activity; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K05625","TGM2; transglutaminase 2 [EC:2.3.2.13]","hsa05016 Huntington's disease - Homo sapiens (human); ","IPR008958; IPR013783; IPR002931; IPR014756; IPR001102; ","\"Transglutaminase, C-terminal; Immunoglobulin-like fold; Transglutaminase-like; Immunoglobulin E-set; Transglutaminase, N-terminal; \"\r"]
["P22061","Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Homo sapiens OX=9606 GN=PCMT1","PCMT1",24.636,65.372,37,8,14,8,1.009,1.01,1.11,0.973,0.965,1.01,0.942,0.165,"cytoplasm\r","GO:0044267 cellular protein metabolic process; GO:0030091 protein repair; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0032259 methylation; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0008213 protein alkylation; GO:0006479 protein methylation; GO:0043414 macromolecule methylation; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:0009987 cellular process; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0050839 cell adhesion molecule binding; GO:0008757 S-adenosylmethionine-dependent methyltransferase activity; GO:0008168 methyltransferase activity; GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity; GO:0008276 protein methyltransferase activity; GO:0010340 carboxyl-O-methyltransferase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0051998 protein carboxyl O-methyltransferase activity; GO:0045296 cadherin binding; GO:0016741 transferase activity, transferring one-carbon groups; GO:0005515 protein binding; GO:0008171 O-methyltransferase activity; GO:0016740 transferase activity; ","K00573",null,null,"IPR029063; ","S-adenosyl-L-methionine-dependent methyltransferase; \r"]
["P22102","Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART","GART",107.77,40.318,10.7,9,12,9,0.857,0.88,0.965,1.118,1.129,1.064,1.225,0.0072,"cytoplasm\r","GO:0051188 cofactor biosynthetic process; GO:0042559 pteridine-containing compound biosynthetic process; GO:0046148 pigment biosynthetic process; GO:0016053 organic acid biosynthetic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0007420 brain development; GO:0009117 nucleotide metabolic process; GO:0042398 cellular modified amino acid biosynthetic process; GO:0044699 single-organism process; GO:0021987 cerebral cortex development; GO:0009058 biosynthetic process; GO:0006544 glycine metabolic process; GO:0009156 ribonucleoside monophosphate biosynthetic process; GO:0046040 IMP metabolic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0021537 telencephalon development; GO:0046390 ribose phosphate biosynthetic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0006753 nucleoside phosphate metabolic process; GO:0046112 nucleobase biosynthetic process; GO:0019693 ribose phosphate metabolic process; GO:0009108 coenzyme biosynthetic process; GO:0060322 head development; GO:0010035 response to inorganic substance; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0018130 heterocycle biosynthetic process; GO:0046653 tetrahydrofolate metabolic process; GO:0009113 purine nucleobase biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0006732 coenzyme metabolic process; GO:0043603 cellular amide metabolic process; GO:0032501 multicellular organismal process; GO:0009168 purine ribonucleoside monophosphate biosynthetic process; GO:0051186 cofactor metabolic process; GO:0021549 cerebellum development; GO:0090407 organophosphate biosynthetic process; GO:0046394 carboxylic acid biosynthetic process; GO:0048513 animal organ development; GO:0042221 response to chemical; GO:0009069 serine family amino acid metabolic process; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0007417 central nervous system development; GO:0044710 single-organism metabolic process; GO:0072522 purine-containing compound biosynthetic process; GO:0009112 nucleobase metabolic process; GO:0006188 IMP biosynthetic process; GO:0022037 metencephalon development; GO:0009126 purine nucleoside monophosphate metabolic process; GO:0006760 folic acid-containing compound metabolic process; GO:0006164 purine nucleotide biosynthetic process; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:0043436 oxoacid metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0021543 pallium development; GO:0044707 single-multicellular organism process; GO:0009165 nucleotide biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0009259 ribonucleotide metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0006575 cellular modified amino acid metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0030900 forebrain development; GO:0046654 tetrahydrofolate biosynthetic process; GO:0007275 multicellular organism development; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0030902 hindbrain development; GO:0009124 nucleoside monophosphate biosynthetic process; GO:0044711 single-organism biosynthetic process; GO:0042440 pigment metabolic process; GO:0048731 system development; GO:0009396 folic acid-containing compound biosynthetic process; GO:0009127 purine nucleoside monophosphate biosynthetic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0010033 response to organic substance; GO:1901605 alpha-amino acid metabolic process; GO:0044238 primary metabolic process; GO:0006144 purine nucleobase metabolic process; GO:1901576 organic substance biosynthetic process; GO:0042558 pteridine-containing compound metabolic process; GO:0006163 purine nucleotide metabolic process; GO:0003360 brainstem development; GO:0044249 cellular biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0009152 purine ribonucleotide biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0006189 'de novo' IMP biosynthetic process; GO:0044767 single-organism developmental process; GO:0044283 small molecule biosynthetic process; GO:0009260 ribonucleotide biosynthetic process; GO:0019752 carboxylic acid metabolic process; GO:0019637 organophosphate metabolic process; GO:0043604 amide biosynthetic process; GO:0009150 purine ribonucleotide metabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0016874 ligase activity; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016741 transferase activity, transferring one-carbon groups; GO:0016882 cyclo-ligase activity; GO:0000166 nucleotide binding; GO:0004641 phosphoribosylformylglycinamidine cyclo-ligase activity; GO:0004637 phosphoribosylamine-glycine ligase activity; GO:0016879 ligase activity, forming carbon-nitrogen bonds; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0016742 hydroxymethyl-, formyl- and related transferase activity; GO:0016740 transferase activity; GO:0004644 phosphoribosylglycinamide formyltransferase activity; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K11787","GART; phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 2.1.2.2 6.3.3.1]","hsa00670 One carbon pool by folate - Homo sapiens (human); hsa00230 Purine metabolism - Homo sapiens (human); hsa01523 Antifolate resistance - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR016188; IPR020560; IPR020561; IPR013815; IPR016185; IPR020562; IPR010918; IPR011761; IPR013816; IPR011054; IPR002376; ","\"PurM-like, N-terminal domain; Phosphoribosylglycinamide synthetase, C-domain; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; ATP-grasp fold, subdomain 1; Pre-ATP-grasp domain; Phosphoribosylglycinamide synthetase, N-terminal; AIR synthase-related protein, C-terminal domain; ATP-grasp fold; ATP-grasp fold, subdomain 2; Rudiment single hybrid motif; Formyl transferase, N-terminal; \"\r"]
["P22234","Multifunctional protein ADE2 OS=Homo sapiens OX=9606 GN=PAICS","PAICS",47.079,76.255,28.5,11,22,11,0.947,0.886,0.917,1.044,1.052,1.129,1.173,0.0072,"cytoplasm\r","GO:0046148 pigment biosynthetic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0009156 ribonucleoside monophosphate biosynthetic process; GO:0046040 IMP metabolic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0046390 ribose phosphate biosynthetic process; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0006753 nucleoside phosphate metabolic process; GO:0046112 nucleobase biosynthetic process; GO:0019693 ribose phosphate metabolic process; GO:0018130 heterocycle biosynthetic process; GO:0009113 purine nucleobase biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009168 purine ribonucleoside monophosphate biosynthetic process; GO:0090407 organophosphate biosynthetic process; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0072522 purine-containing compound biosynthetic process; GO:0009112 nucleobase metabolic process; GO:0006188 IMP biosynthetic process; GO:0009126 purine nucleoside monophosphate metabolic process; GO:0006164 purine nucleotide biosynthetic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0009165 nucleotide biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0009259 ribonucleotide metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0009124 nucleoside monophosphate biosynthetic process; GO:0044711 single-organism biosynthetic process; GO:0042440 pigment metabolic process; GO:0009127 purine nucleoside monophosphate biosynthetic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0044238 primary metabolic process; GO:0006144 purine nucleobase metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0006163 purine nucleotide metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0009152 purine ribonucleotide biosynthetic process; GO:0006189 'de novo' IMP biosynthetic process; GO:0009260 ribonucleotide biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0009123 nucleoside monophosphate metabolic process; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0016874 ligase activity; GO:0005515 protein binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0016830 carbon-carbon lyase activity; GO:0005488 binding; GO:0045296 cadherin binding; GO:0032550 purine ribonucleoside binding; GO:0016831 carboxy-lyase activity; GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0016829 lyase activity; GO:0000166 nucleotide binding; GO:0016881 acid-amino acid ligase activity; GO:0004638 phosphoribosylaminoimidazole carboxylase activity; GO:0016879 ligase activity, forming carbon-nitrogen bonds; GO:0032549 ribonucleoside binding; GO:0050839 cell adhesion molecule binding; GO:0097367 carbohydrate derivative binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; ","K01587","PAICS; phosphoribosylaminoimidazole carboxylase / phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:4.1.1.21 6.3.2.6]","hsa00230 Purine metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR033626; IPR028923; IPR000031; IPR013816; ","\"Class II PurE; SAICAR synthetase/ADE2, N-terminal; PurE domain; ATP-grasp fold, subdomain 2; \"\r"]
["P22352","Glutathione peroxidase 3 OS=Homo sapiens OX=9606 GN=GPX3","GPX3",25.552,62.46,35.4,8,22,8,1.071,1.034,1.097,0.937,0.951,0.951,0.887,0.00256,"extracellular\r","GO:0044085 cellular component biogenesis; GO:0016043 cellular component organization; GO:0033194 response to hydroperoxide; GO:0051260 protein homooligomerization; GO:1901700 response to oxygen-containing compound; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0051259 protein oligomerization; GO:0008152 metabolic process; GO:0051289 protein homotetramerization; GO:0042743 hydrogen peroxide metabolic process; GO:1990748 cellular detoxification; GO:0072593 reactive oxygen species metabolic process; GO:0022607 cellular component assembly; GO:0051262 protein tetramerization; GO:0065003 macromolecular complex assembly; GO:0006979 response to oxidative stress; GO:0044248 cellular catabolic process; GO:0006982 response to lipid hydroperoxide; GO:0098869 cellular oxidant detoxification; GO:0042744 hydrogen peroxide catabolic process; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0071822 protein complex subunit organization; GO:0006950 response to stress; GO:0055114 oxidation-reduction process; GO:0000302 response to reactive oxygen species; GO:0009636 response to toxic substance; GO:0010033 response to organic substance; GO:0043933 macromolecular complex subunit organization; GO:0042221 response to chemical; GO:0044710 single-organism metabolic process; GO:0070271 protein complex biogenesis; GO:0009056 catabolic process; GO:0098754 detoxification; GO:0071840 cellular component organization or biogenesis; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:0004602 glutathione peroxidase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016209 antioxidant activity; GO:0005515 protein binding; GO:0004601 peroxidase activity; GO:0008430 selenium binding; GO:0008134 transcription factor binding; GO:0016684 oxidoreductase activity, acting on peroxide as acceptor; GO:0016491 oxidoreductase activity; ","K00432","gpx; glutathione peroxidase [EC:1.11.1.9]","hsa00480 Glutathione metabolism - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04918 Thyroid hormone synthesis - Homo sapiens (human); hsa05014 Amyotrophic lateral sclerosis (ALS) - Homo sapiens (human); hsa00590 Arachidonic acid metabolism - Homo sapiens (human); ","IPR012336; ","Thioredoxin-like fold; \r"]
["P22415","Upstream stimulatory factor 1 OS=Homo sapiens OX=9606 GN=USF1","USF1",33.538,1.8441,2.6,1,1,1,1.123,0.873,0.686,0.919,1.268,1.125,1.235,0.262,"nucleus\r","GO:0065008 regulation of biological quality; GO:0097659 nucleic acid-templated transcription; GO:0042593 glucose homeostasis; GO:0009891 positive regulation of biosynthetic process; GO:0044237 cellular metabolic process; GO:0006006 glucose metabolic process; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0019086 late viral transcription; GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus; GO:0009719 response to endogenous stimulus; GO:0090303 positive regulation of wound healing; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:1901652 response to peptide; GO:0055088 lipid homeostasis; GO:0030194 positive regulation of blood coagulation; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044281 small molecule metabolic process; GO:0032774 RNA biosynthetic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0031323 regulation of cellular metabolic process; GO:0005975 carbohydrate metabolic process; GO:0051704 multi-organism process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0010243 response to organonitrogen compound; GO:0000429 carbon catabolite regulation of transcription from RNA polymerase II promoter; GO:0046015 regulation of transcription by glucose; GO:1900048 positive regulation of hemostasis; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0032869 cellular response to insulin stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:1903036 positive regulation of response to wounding; GO:0050794 regulation of cellular process; GO:0009628 response to abiotic stimulus; GO:1901700 response to oxygen-containing compound; GO:0030193 regulation of blood coagulation; GO:0048519 negative regulation of biological process; GO:0080134 regulation of response to stress; GO:0051239 regulation of multicellular organismal process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0070482 response to oxygen levels; GO:0033500 carbohydrate homeostasis; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0048878 chemical homeostasis; GO:0051254 positive regulation of RNA metabolic process; GO:0009416 response to light stimulus; GO:0006950 response to stress; GO:0051917 regulation of fibrinolysis; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0071496 cellular response to external stimulus; GO:0032101 regulation of response to external stimulus; GO:0010033 response to organic substance; GO:0007584 response to nutrient; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0031668 cellular response to extracellular stimulus; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0061041 regulation of wound healing; GO:0031670 cellular response to nutrient; GO:0031325 positive regulation of cellular metabolic process; GO:0036293 response to decreased oxygen levels; GO:0031328 positive regulation of cellular biosynthetic process; GO:0048584 positive regulation of response to stimulus; GO:1903034 regulation of response to wounding; GO:0000436 carbon catabolite activation of transcription from RNA polymerase II promoter; GO:0019318 hexose metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:2001141 regulation of RNA biosynthetic process; GO:1901653 cellular response to peptide; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0032103 positive regulation of response to external stimulus; GO:1900046 regulation of hemostasis; GO:0009314 response to radiation; GO:0045990 carbon catabolite regulation of transcription; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0070887 cellular response to chemical stimulus; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0000430 regulation of transcription from RNA polymerase II promoter by glucose; GO:0071417 cellular response to organonitrogen compound; GO:0016070 RNA metabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0032868 response to insulin; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0043434 response to peptide hormone; GO:0090304 nucleic acid metabolic process; GO:1901699 cellular response to nitrogen compound; GO:0006351 transcription, DNA-templated; GO:0032870 cellular response to hormone stimulus; GO:0019222 regulation of metabolic process; GO:0019083 viral transcription; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0051918 negative regulation of fibrinolysis; GO:0019058 viral life cycle; GO:0050896 response to stimulus; GO:0031669 cellular response to nutrient levels; GO:0045991 carbon catabolite activation of transcription; GO:0071704 organic substance metabolic process; GO:0009991 response to extracellular stimulus; GO:0042592 homeostatic process; GO:0000432 positive regulation of transcription from RNA polymerase II promoter by glucose; GO:0016032 viral process; GO:0071375 cellular response to peptide hormone stimulus; GO:0001666 response to hypoxia; GO:0005996 monosaccharide metabolic process; GO:0019080 viral gene expression; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0046016 positive regulation of transcription by glucose; GO:0050878 regulation of body fluid levels; GO:0006355 regulation of transcription, DNA-templated; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0050820 positive regulation of coagulation; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0050818 regulation of coagulation; GO:1901701 cellular response to oxygen-containing compound; GO:0009411 response to UV; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0071495 cellular response to endogenous stimulus; GO:0006366 transcription from RNA polymerase II promoter; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0010467 gene expression; GO:0031667 response to nutrient levels; GO:0009725 response to hormone; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005667 transcription factor complex; GO:0005623 cell; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0000785 chromatin; GO:0044454 nuclear chromosome part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005694 chromosome; GO:0000790 nuclear chromatin; GO:0000228 nuclear chromosome; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0003677 DNA binding; GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding; GO:0046982 protein heterodimerization activity; GO:0003690 double-stranded DNA binding; GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding; GO:0019901 protein kinase binding; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:0043565 sequence-specific DNA binding; GO:0019900 kinase binding; GO:0003700 transcription factor activity, sequence-specific DNA binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0042802 identical protein binding; GO:0042826 histone deacetylase binding; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0001071 nucleic acid binding transcription factor activity; GO:0003676 nucleic acid binding; GO:0043425 bHLH transcription factor binding; GO:0008134 transcription factor binding; GO:0019899 enzyme binding; ","K09106",null,null,"IPR011598; ","\"Myc-type, basic helix-loop-helix (bHLH) domain; \"\r"]
["P22528","Cornifin-B OS=Homo sapiens OX=9606 GN=SPRR1B","SPRR1B",9.8875,10.752,61.8,4,9,1,0.525,0.394,0.471,1.605,1.421,1.528,3.276,0.000197,"extracellular\r","GO:0044707 single-multicellular organism process; GO:0031424 keratinization; GO:0048869 cellular developmental process; GO:0018149 peptide cross-linking; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0009913 epidermal cell differentiation; GO:0008152 metabolic process; GO:0030154 cell differentiation; GO:0008544 epidermis development; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0043588 skin development; GO:0009888 tissue development; GO:0030216 keratinocyte differentiation; GO:0048731 system development; GO:0070268 cornification; GO:0044763 single-organism cellular process; GO:0044238 primary metabolic process; GO:0032501 multicellular organismal process; GO:0048513 animal organ development; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0012501 programmed cell death; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:0048856 anatomical structure development; GO:0030855 epithelial cell differentiation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0001533 cornified envelope; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0060090 binding, bridging; GO:0030674 protein binding, bridging; GO:0005198 structural molecule activity; GO:0005488 binding; "]
["P22694","cAMP-dependent protein kinase catalytic subunit beta OS=Homo sapiens OX=9606 GN=PRKACB","PRKACB",40.622,2.3612,12.3,5,7,1,1.074,1.103,0.952,0.954,1.019,0.915,0.923,0.224,"cyto_mito\r","GO:0044700 single organism signaling; GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0002220 innate immune response activating cell surface receptor signaling pathway; GO:0007166 cell surface receptor signaling pathway; GO:0035148 tube formation; GO:0043009 chordate embryonic development; GO:0031347 regulation of defense response; GO:0044237 cellular metabolic process; GO:0042157 lipoprotein metabolic process; GO:0008152 metabolic process; GO:0044093 positive regulation of molecular function; GO:0009719 response to endogenous stimulus; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0051347 positive regulation of transferase activity; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009790 embryo development; GO:1901652 response to peptide; GO:0048598 embryonic morphogenesis; GO:0007399 nervous system development; GO:0014070 response to organic cyclic compound; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0051174 regulation of phosphorus metabolic process; GO:0002758 innate immune response-activating signal transduction; GO:0080090 regulation of primary metabolic process; GO:0035239 tube morphogenesis; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0050776 regulation of immune response; GO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway; GO:0010243 response to organonitrogen compound; GO:0002223 stimulatory C-type lectin receptor signaling pathway; GO:0030104 water homeostasis; GO:0050790 regulation of catalytic activity; GO:2000242 negative regulation of reproductive process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:1901698 response to nitrogen compound; GO:0051447 negative regulation of meiotic cell cycle; GO:0010604 positive regulation of macromolecule metabolic process; GO:0002682 regulation of immune system process; GO:0006464 cellular protein modification process; GO:1903317 regulation of protein maturation; GO:0050817 coagulation; GO:0050794 regulation of cellular process; GO:0002009 morphogenesis of an epithelium; GO:0016310 phosphorylation; GO:0044707 single-multicellular organism process; GO:0008589 regulation of smoothened signaling pathway; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0031399 regulation of protein modification process; GO:1901700 response to oxygen-containing compound; GO:0044267 cellular protein metabolic process; GO:0080134 regulation of response to stress; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0051239 regulation of multicellular organismal process; GO:0009653 anatomical structure morphogenesis; GO:0060606 tube closure; GO:0031349 positive regulation of defense response; GO:0023057 negative regulation of signaling; GO:0045992 negative regulation of embryonic development; GO:0010648 negative regulation of cell communication; GO:0032147 activation of protein kinase activity; GO:0051338 regulation of transferase activity; GO:0007275 multicellular organism development; GO:0016331 morphogenesis of embryonic epithelium; GO:0034199 activation of protein kinase A activity; GO:0050778 positive regulation of immune response; GO:0009966 regulation of signal transduction; GO:0001843 neural tube closure; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0048878 chemical homeostasis; GO:0002253 activation of immune response; GO:0060562 epithelial tube morphogenesis; GO:0006950 response to stress; GO:0048731 system development; GO:0051960 regulation of nervous system development; GO:0003014 renal system process; GO:0002376 immune system process; GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning; GO:0030162 regulation of proteolysis; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0007186 G-protein coupled receptor signaling pathway; GO:0051247 positive regulation of protein metabolic process; GO:0006793 phosphorus metabolic process; GO:0050891 multicellular organismal water homeostasis; GO:0031325 positive regulation of cellular metabolic process; GO:0070613 regulation of protein processing; GO:0033762 response to glucagon; GO:0048584 positive regulation of response to stimulus; GO:0043412 macromolecule modification; GO:0050793 regulation of developmental process; GO:0051445 regulation of meiotic cell cycle; GO:0001841 neural tube formation; GO:0051093 negative regulation of developmental process; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0048871 multicellular organismal homeostasis; GO:0006796 phosphate-containing compound metabolic process; GO:0009611 response to wounding; GO:0007165 signal transduction; GO:0048729 tissue morphogenesis; GO:0010646 regulation of cell communication; GO:1901653 cellular response to peptide; GO:0007154 cell communication; GO:0045088 regulation of innate immune response; GO:0009893 positive regulation of metabolic process; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0033674 positive regulation of kinase activity; GO:0051726 regulation of cell cycle; GO:0070887 cellular response to chemical stimulus; GO:0097338 response to clozapine; GO:0003091 renal water homeostasis; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0035295 tube development; GO:0060429 epithelium development; GO:0045937 positive regulation of phosphate metabolic process; GO:0009888 tissue development; GO:0045879 negative regulation of smoothened signaling pathway; GO:0048522 positive regulation of cellular process; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0071417 cellular response to organonitrogen compound; GO:2000241 regulation of reproductive process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0043434 response to peptide hormone; GO:1901699 cellular response to nitrogen compound; GO:0032870 cellular response to hormone stimulus; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0043549 regulation of kinase activity; GO:2000026 regulation of multicellular organismal development; GO:0045859 regulation of protein kinase activity; GO:0045786 negative regulation of cell cycle; GO:0002218 activation of innate immune response; GO:0060255 regulation of macromolecule metabolic process; GO:1901620 regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning; GO:0071310 cellular response to organic substance; GO:0050896 response to stimulus; GO:0021915 neural tube development; GO:0007599 hemostasis; GO:0071704 organic substance metabolic process; GO:0072175 epithelial tube formation; GO:0071377 cellular response to glucagon stimulus; GO:0042592 homeostatic process; GO:0006468 protein phosphorylation; GO:0051961 negative regulation of nervous system development; GO:0071375 cellular response to peptide hormone stimulus; GO:0002757 immune response-activating signal transduction; GO:0009987 cellular process; GO:0045089 positive regulation of innate immune response; GO:0050878 regulation of body fluid levels; GO:0003008 system process; GO:0009792 embryo development ending in birth or egg hatching; GO:0001932 regulation of protein phosphorylation; GO:0031401 positive regulation of protein modification process; GO:0048585 negative regulation of response to stimulus; GO:0001934 positive regulation of protein phosphorylation; GO:0045860 positive regulation of protein kinase activity; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0001838 embryonic epithelial tube formation; GO:0014020 primary neural tube formation; GO:1901701 cellular response to oxygen-containing compound; GO:0045995 regulation of embryonic development; GO:0042060 wound healing; GO:0071495 cellular response to endogenous stimulus; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0002684 positive regulation of immune system process; GO:0009725 response to hormone; GO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0005815 microtubule organizing center; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0044441 ciliary part; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097546 ciliary base; GO:0043229 intracellular organelle; GO:0005929 cilium; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0005952 cAMP-dependent protein kinase complex; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005813 centrosome; GO:0045171 intercellular bridge; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0031625 ubiquitin protein ligase binding; GO:0005515 protein binding; GO:0004672 protein kinase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016301 kinase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0004691 cAMP-dependent protein kinase activity; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0004690 cyclic nucleotide-dependent protein kinase activity; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0000287 magnesium ion binding; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0046872 metal ion binding; GO:0004674 protein serine/threonine kinase activity; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0019899 enzyme binding; GO:0036094 small molecule binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K04345","PKA; protein kinase A [EC:2.7.11.11]","hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human); hsa04530 Tight junction - Homo sapiens (human); hsa04014 Ras signaling pathway - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa04970 Salivary secretion - Homo sapiens (human); hsa04962 Vasopressin-regulated water reabsorption - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa04934 Cushing's syndrome - Homo sapiens (human); hsa04922 Glucagon signaling pathway - Homo sapiens (human); hsa04211 Longevity regulating pathway - Homo sapiens (human); hsa04611 Platelet activation - Homo sapiens (human); hsa04340 Hedgehog signaling pathway - Homo sapiens (human); hsa04971 Gastric acid secretion - Homo sapiens (human); hsa04914 Progesterone-mediated oocyte maturation - Homo sapiens (human); hsa04725 Cholinergic synapse - Homo sapiens (human); hsa04921 Oxytocin signaling pathway - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); hsa04371 Apelin signaling pathway - Homo sapiens (human); hsa05031 Amphetamine addiction - Homo sapiens (human); hsa04916 Melanogenesis - Homo sapiens (human); hsa04020 Calcium signaling pathway - Homo sapiens (human); hsa04270 Vascular smooth muscle contraction - Homo sapiens (human); hsa04923 Regulation of lipolysis in adipocytes - Homo sapiens (human); hsa04010 MAPK signaling pathway - Homo sapiens (human); hsa04750 Inflammatory mediator regulation of TRP channels - Homo sapiens (human); hsa04740 Olfactory transduction - Homo sapiens (human); hsa05414 Dilated cardiomyopathy (DCM) - Homo sapiens (human); hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human); hsa04540 Gap junction - Homo sapiens (human); hsa04912 GnRH signaling pathway - Homo sapiens (human); hsa04727 GABAergic synapse - Homo sapiens (human); hsa05020 Prion diseases - Homo sapiens (human); hsa05203 Viral carcinogenesis - Homo sapiens (human); hsa04742 Taste transduction - Homo sapiens (human); hsa04720 Long-term potentiation - Homo sapiens (human); hsa04713 Circadian entrainment - Homo sapiens (human); hsa04928 Parathyroid hormone synthesis, secretion and action - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa05166 HTLV-I infection - Homo sapiens (human); hsa04924 Renin secretion - Homo sapiens (human); hsa05110 Vibrio cholerae infection - Homo sapiens (human); hsa04976 Bile secretion - Homo sapiens (human); hsa04911 Insulin secretion - Homo sapiens (human); hsa04724 Glutamatergic synapse - Homo sapiens (human); hsa04140 Autophagy - animal - Homo sapiens (human); hsa04114 Oocyte meiosis - Homo sapiens (human); hsa01522 Endocrine resistance - Homo sapiens (human); hsa05034 Alcoholism - Homo sapiens (human); hsa04927 Cortisol synthesis and secretion - Homo sapiens (human); hsa04915 Estrogen signaling pathway - Homo sapiens (human); hsa04310 Wnt signaling pathway - Homo sapiens (human); hsa05032 Morphine addiction - Homo sapiens (human); hsa04728 Dopaminergic synapse - Homo sapiens (human); hsa04910 Insulin signaling pathway - Homo sapiens (human); hsa04024 cAMP signaling pathway - Homo sapiens (human); hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa05030 Cocaine addiction - Homo sapiens (human); hsa04726 Serotonergic synapse - Homo sapiens (human); hsa04213 Longevity regulating pathway - multiple species - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); hsa04062 Chemokine signaling pathway - Homo sapiens (human); hsa04925 Aldosterone synthesis and secretion - Homo sapiens (human); hsa04913 Ovarian steroidogenesis - Homo sapiens (human); hsa05146 Amoebiasis - Homo sapiens (human); hsa04918 Thyroid hormone synthesis - Homo sapiens (human); hsa04926 Relaxin signaling pathway - Homo sapiens (human); hsa04961 Endocrine and other factor-regulated calcium reabsorption - Homo sapiens (human); ","IPR000719; IPR011009; IPR000961; ","\"Protein kinase domain; Protein kinase-like domain; AGC-kinase, C-terminal; \"\r"]
["P22695","Cytochrome b-c1 complex subunit 2, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC2","UQCRC2",48.442,203.72,50.6,18,31,18,1.036,0.962,1.025,0.99,0.964,0.972,0.968,0.259,"mitochondria\r","GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0072594 establishment of protein localization to organelle; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0006839 mitochondrial transport; GO:0044699 single-organism process; GO:0016485 protein processing; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0015031 protein transport; GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0006091 generation of precursor metabolites and energy; GO:0006753 nucleoside phosphate metabolic process; GO:0007005 mitochondrion organization; GO:0019693 ribose phosphate metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0033365 protein localization to organelle; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006119 oxidative phosphorylation; GO:0072521 purine-containing compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0006810 transport; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0044260 cellular macromolecule metabolic process; GO:0022900 electron transport chain; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0072655 establishment of protein localization to mitochondrion; GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0016310 phosphorylation; GO:0006725 cellular aromatic compound metabolic process; GO:0042773 ATP synthesis coupled electron transport; GO:0009259 ribonucleotide metabolic process; GO:0044267 cellular protein metabolic process; GO:0022904 respiratory electron transport chain; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0006886 intracellular protein transport; GO:0006626 protein targeting to mitochondrion; GO:1901135 carbohydrate derivative metabolic process; GO:0006508 proteolysis; GO:0034641 cellular nitrogen compound metabolic process; GO:0034613 cellular protein localization; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0009119 ribonucleoside metabolic process; GO:0034982 mitochondrial protein processing; GO:0006627 protein processing involved in protein targeting to mitochondrion; GO:0046034 ATP metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0070585 protein localization to mitochondrion; GO:0045333 cellular respiration; GO:0006163 purine nucleotide metabolic process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0046128 purine ribonucleoside metabolic process; GO:0070727 cellular macromolecule localization; GO:0006793 phosphorus metabolic process; GO:0009060 aerobic respiration; GO:0006996 organelle organization; GO:0019637 organophosphate metabolic process; GO:0010467 gene expression; GO:0009150 purine ribonucleotide metabolic process; GO:0051604 protein maturation; GO:0051179 localization; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:1901564 organonitrogen compound metabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0043209 myelin sheath; GO:0044425 membrane part; GO:0005750 mitochondrial respiratory chain complex III; GO:0005622 intracellular; GO:0044464 cell part; GO:0019866 organelle inner membrane; GO:1903561 extracellular vesicle; GO:1990351 transporter complex; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0098803 respiratory chain complex; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0070069 cytochrome complex; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:1902495 transmembrane transporter complex; GO:0016021 integral component of membrane; GO:0045275 respiratory chain complex III; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005746 mitochondrial respiratory chain; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:1990204 oxidoreductase complex; GO:0031975 envelope; GO:0043234 protein complex; GO:0070469 respiratory chain; GO:0031966 mitochondrial membrane; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0004222 metalloendopeptidase activity; GO:0008233 peptidase activity; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0008237 metallopeptidase activity; GO:0008270 zinc ion binding; GO:0004175 endopeptidase activity; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0032403 protein complex binding; ","K00415","QCR2; ubiquinol-cytochrome c reductase core subunit 2","hsa04260 Cardiac muscle contraction - Homo sapiens (human); hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); ","IPR007863; IPR011765; IPR011249; IPR011237; ","\"Peptidase M16, C-terminal; Peptidase M16, N-terminal; Metalloenzyme, LuxS/M16 peptidase-like; Peptidase M16 domain; \"\r"]
["P22830","Ferrochelatase, mitochondrial OS=Homo sapiens OX=9606 GN=FECH","FECH",47.862,22.049,14.2,5,6,5,0.995,1.056,0.929,0.984,0.999,1.011,1.005,0.882,"mitochondria\r","GO:0051188 cofactor biosynthetic process; GO:0046148 pigment biosynthetic process; GO:0071384 cellular response to corticosteroid stimulus; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0046685 response to arsenic-containing substance; GO:0071383 cellular response to steroid hormone stimulus; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0071549 cellular response to dexamethasone stimulus; GO:0048545 response to steroid hormone; GO:0009719 response to endogenous stimulus; GO:0009314 response to radiation; GO:0051597 response to methylmercury; GO:0010035 response to inorganic substance; GO:0070887 cellular response to chemical stimulus; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0009636 response to toxic substance; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0051384 response to glucocorticoid; GO:0071396 cellular response to lipid; GO:0010038 response to metal ion; GO:0051186 cofactor metabolic process; GO:0042221 response to chemical; GO:0032870 cellular response to hormone stimulus; GO:0044710 single-organism metabolic process; GO:0033013 tetrapyrrole metabolic process; GO:0010288 response to lead ion; GO:0033014 tetrapyrrole biosynthetic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0070541 response to platinum ion; GO:0006725 cellular aromatic compound metabolic process; GO:0009628 response to abiotic stimulus; GO:0045471 response to ethanol; GO:0006783 heme biosynthetic process; GO:0071310 cellular response to organic substance; GO:1901700 response to oxygen-containing compound; GO:0046501 protoporphyrinogen IX metabolic process; GO:0050896 response to stimulus; GO:0042168 heme metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0042493 response to drug; GO:0033993 response to lipid; GO:0006778 porphyrin-containing compound metabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0031960 response to corticosteroid; GO:0034641 cellular nitrogen compound metabolic process; GO:0009987 cellular process; GO:1901655 cellular response to ketone; GO:0044711 single-organism biosynthetic process; GO:0009416 response to light stimulus; GO:0071385 cellular response to glucocorticoid stimulus; GO:0042440 pigment metabolic process; GO:0017085 response to insecticide; GO:0006779 porphyrin-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0097305 response to alcohol; GO:0071407 cellular response to organic cyclic compound; GO:0010033 response to organic substance; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0071548 response to dexamethasone; GO:1901701 cellular response to oxygen-containing compound; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0071495 cellular response to endogenous stimulus; GO:0009725 response to hormone; GO:1901654 response to ketone; GO:1901564 organonitrogen compound metabolic process; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044429 mitochondrial part; GO:0031090 organelle membrane; GO:0031967 organelle envelope; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0031975 envelope; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0051537 2 iron, 2 sulfur cluster binding; GO:0005506 iron ion binding; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0004325 ferrochelatase activity; GO:0005488 binding; GO:0051536 iron-sulfur cluster binding; GO:0043167 ion binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0016829 lyase activity; GO:0005515 protein binding; GO:0008198 ferrous iron binding; GO:0051540 metal cluster binding; ","K01772","hemH; protoporphyrin/coproporphyrin ferrochelatase [EC:4.99.1.1 4.99.1.9]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00860 Porphyrin and chlorophyll metabolism - Homo sapiens (human); ","IPR033644; IPR033659; ","\"Ferrochelatase, C-terminal; Ferrochelatase, N-terminal; \"\r"]
["P23083","Immunoglobulin heavy variable 1-2 OS=Homo sapiens OX=9606 GN=IGHV1-2","IGHV1-2",13.085,3.5762,11.1,1,1,1,0.835,0.895,0.809,1.022,1.215,1.208,1.357,0.00914,"extracellular\r","GO:0044700 single organism signaling; GO:0016064 immunoglobulin mediated immune response; GO:0051674 localization of cell; GO:0007166 cell surface receptor signaling pathway; GO:0038094 Fc-gamma receptor signaling pathway; GO:0044699 single-organism process; GO:0006909 phagocytosis; GO:0051234 establishment of localization; GO:0006956 complement activation; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0007154 cell communication; GO:0002250 adaptive immune response; GO:0006958 complement activation, classical pathway; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0044765 single-organism transport; GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0044763 single-organism cellular process; GO:0048870 cell motility; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0002455 humoral immune response mediated by circulating immunoglobulin; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0050900 leukocyte migration; GO:0048583 regulation of response to stimulus; GO:0002682 regulation of immune system process; GO:0002431 Fc receptor mediated stimulatory signaling pathway; GO:0040011 locomotion; GO:0050794 regulation of cellular process; GO:0016477 cell migration; GO:0002252 immune effector process; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0006959 humoral immune response; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0019724 B cell mediated immunity; GO:1902578 single-organism localization; GO:0002757 immune response-activating signal transduction; GO:0006508 proteolysis; GO:0006898 receptor-mediated endocytosis; GO:0002449 lymphocyte mediated immunity; GO:0038093 Fc receptor signaling pathway; GO:0050778 positive regulation of immune response; GO:0009987 cellular process; GO:0002253 activation of immune response; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0072376 protein activation cascade; GO:0044238 primary metabolic process; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0002684 positive regulation of immune system process; GO:0038095 Fc-epsilon receptor signaling pathway; GO:0006928 movement of cell or subcellular component; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis; GO:0051179 localization; GO:0006955 immune response; GO:0048584 positive regulation of response to stimulus; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005623 cell; GO:0044464 cell part; GO:0071944 cell periphery; GO:0005576 extracellular region; GO:0005886 plasma membrane; ","GO:0004252 serine-type endopeptidase activity; GO:0004175 endopeptidase activity; GO:0008233 peptidase activity; GO:0003824 catalytic activity; GO:0017171 serine hydrolase activity; GO:0005488 binding; GO:0008236 serine-type peptidase activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0003823 antigen binding; ",{"$nulls":3},"IPR007110; IPR013783; IPR013106; ","Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin V-set domain; \r"]
["P23219","Prostaglandin G/H synthase 1 OS=Homo sapiens OX=9606 GN=PTGS1","PTGS1",68.686,15.96,12.2,6,6,6,0.951,0.922,0.975,0.992,1.016,1.141,1.106,0.0989,"extracellular\r","GO:0065008 regulation of biological quality; GO:0016053 organic acid biosynthetic process; GO:1901568 fatty acid derivative metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0008610 lipid biosynthetic process; GO:0046456 icosanoid biosynthetic process; GO:0008152 metabolic process; GO:0006979 response to oxidative stress; GO:0032787 monocarboxylic acid metabolic process; GO:0098869 cellular oxidant detoxification; GO:0070887 cellular response to chemical stimulus; GO:0006690 icosanoid metabolic process; GO:0006629 lipid metabolic process; GO:0051716 cellular response to stimulus; GO:0055114 oxidation-reduction process; GO:0046457 prostanoid biosynthetic process; GO:0009636 response to toxic substance; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006636 unsaturated fatty acid biosynthetic process; GO:0032501 multicellular organismal process; GO:0006633 fatty acid biosynthetic process; GO:0046394 carboxylic acid biosynthetic process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0044710 single-organism metabolic process; GO:0006954 inflammatory response; GO:0006693 prostaglandin metabolic process; GO:0006952 defense response; GO:0003013 circulatory system process; GO:0006082 organic acid metabolic process; GO:0098754 detoxification; GO:0043436 oxoacid metabolic process; GO:0033559 unsaturated fatty acid metabolic process; GO:0019371 cyclooxygenase pathway; GO:0008217 regulation of blood pressure; GO:0050794 regulation of cellular process; GO:0071466 cellular response to xenobiotic stimulus; GO:0019369 arachidonic acid metabolic process; GO:0042127 regulation of cell proliferation; GO:0050896 response to stimulus; GO:0001516 prostaglandin biosynthetic process; GO:0071704 organic substance metabolic process; GO:1990748 cellular detoxification; GO:0009410 response to xenobiotic stimulus; GO:0006805 xenobiotic metabolic process; GO:0008015 blood circulation; GO:0009987 cellular process; GO:0003008 system process; GO:0044711 single-organism biosynthetic process; GO:0006950 response to stress; GO:0006692 prostanoid metabolic process; GO:1901570 fatty acid derivative biosynthetic process; GO:0006631 fatty acid metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0001676 long-chain fatty acid metabolic process; GO:0044283 small molecule biosynthetic process; GO:0019752 carboxylic acid metabolic process; GO:0072330 monocarboxylic acid biosynthetic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0097730 non-motile cilium; GO:0044424 intracellular part; GO:0005623 cell; GO:0097731 9+0 non-motile cilium; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0044441 ciliary part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0001750 photoreceptor outer segment; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0005789 endoplasmic reticulum membrane; GO:0043229 intracellular organelle; GO:0005929 cilium; GO:0042995 cell projection; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044463 cell projection part; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044432 endoplasmic reticulum part; GO:0097733 photoreceptor cell cilium; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0043167 ion binding; GO:0016209 antioxidant activity; GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; GO:0005515 protein binding; GO:0016491 oxidoreductase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0020037 heme binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0051213 dioxygenase activity; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0004601 peroxidase activity; GO:0004666 prostaglandin-endoperoxide synthase activity; GO:0046906 tetrapyrrole binding; GO:0016684 oxidoreductase activity, acting on peroxide as acceptor; ","K00509","PTGS1; prostaglandin-endoperoxide synthase 1 [EC:1.14.99.1]","hsa04923 Regulation of lipolysis in adipocytes - Homo sapiens (human); hsa04611 Platelet activation - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa04726 Serotonergic synapse - Homo sapiens (human); hsa00590 Arachidonic acid metabolism - Homo sapiens (human); ","IPR000742; ","EGF-like domain; \r"]
["P23229","Integrin alpha-6 OS=Homo sapiens OX=9606 GN=ITGA6","ITGA6",126.6,84.968,18.3,18,26,18,1.014,1.052,1.017,0.975,0.963,0.966,0.942,0.0085,"peroxisome\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0010941 regulation of cell death; GO:0030335 positive regulation of cell migration; GO:0046847 filopodium assembly; GO:0007166 cell surface receptor signaling pathway; GO:0009891 positive regulation of biosynthetic process; GO:0009605 response to external stimulus; GO:0022610 biological adhesion; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0007160 cell-matrix adhesion; GO:0007155 cell adhesion; GO:0010562 positive regulation of phosphorus metabolic process; GO:0042327 positive regulation of phosphorylation; GO:0060173 limb development; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0043588 skin development; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044763 single-organism cellular process; GO:0048870 cell motility; GO:0051272 positive regulation of cellular component movement; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0010811 positive regulation of cell-substrate adhesion; GO:2001234 negative regulation of apoptotic signaling pathway; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0050900 leukocyte migration; GO:0051336 regulation of hydrolase activity; GO:0010668 ectodermal cell differentiation; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0098602 single organism cell adhesion; GO:0010604 positive regulation of macromolecule metabolic process; GO:0009887 animal organ morphogenesis; GO:0060548 negative regulation of cell death; GO:0043068 positive regulation of programmed cell death; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0043067 regulation of programmed cell death; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:2000147 positive regulation of cell motility; GO:0009653 anatomical structure morphogenesis; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0051345 positive regulation of hydrolase activity; GO:0043062 extracellular structure organization; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:2000145 regulation of cell motility; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0007275 multicellular organism development; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0009966 regulation of signal transduction; GO:0051254 positive regulation of RNA metabolic process; GO:0045785 positive regulation of cell adhesion; GO:0043547 positive regulation of GTPase activity; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0055123 digestive system development; GO:0002376 immune system process; GO:0071496 cellular response to external stimulus; GO:0071407 cellular response to organic cyclic compound; GO:2001237 negative regulation of extrinsic apoptotic signaling pathway; GO:0030334 regulation of cell migration; GO:0010033 response to organic substance; GO:0030155 regulation of cell adhesion; GO:0030031 cell projection assembly; GO:0031668 cellular response to extracellular stimulus; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0048565 digestive tract development; GO:0097186 amelogenesis; GO:0031325 positive regulation of cellular metabolic process; GO:0006928 movement of cell or subcellular component; GO:0051179 localization; GO:0010810 regulation of cell-substrate adhesion; GO:0031328 positive regulation of cellular biosynthetic process; GO:0051674 localization of cell; GO:0009968 negative regulation of signal transduction; GO:0040017 positive regulation of locomotion; GO:0033627 cell adhesion mediated by integrin; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:2001141 regulation of RNA biosynthetic process; GO:2001233 regulation of apoptotic signaling pathway; GO:0007165 signal transduction; GO:0016337 single organismal cell-cell adhesion; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0042475 odontogenesis of dentin-containing tooth; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0030198 extracellular matrix organization; GO:0050873 brown fat cell differentiation; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0035295 tube development; GO:0010468 regulation of gene expression; GO:0007044 cell-substrate junction assembly; GO:0009888 tissue development; GO:0045937 positive regulation of phosphate metabolic process; GO:0031326 regulation of cellular biosynthetic process; GO:0098609 cell-cell adhesion; GO:0048522 positive regulation of cellular process; GO:0007229 integrin-mediated signaling pathway; GO:0023052 signaling; GO:0010942 positive regulation of cell death; GO:0042476 odontogenesis; GO:0001655 urogenital system development; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0030030 cell projection organization; GO:0031581 hemidesmosome assembly; GO:2001236 regulation of extrinsic apoptotic signaling pathway; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0040011 locomotion; GO:0019220 regulation of phosphate metabolic process; GO:0045444 fat cell differentiation; GO:0048856 anatomical structure development; GO:0016477 cell migration; GO:0016043 cellular component organization; GO:0034329 cell junction assembly; GO:0043069 negative regulation of programmed cell death; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0043065 positive regulation of apoptotic process; GO:0035878 nail development; GO:0072001 renal system development; GO:0050896 response to stimulus; GO:0009991 response to extracellular stimulus; GO:0030154 cell differentiation; GO:0043066 negative regulation of apoptotic process; GO:0007398 ectoderm development; GO:0009987 cellular process; GO:0006355 regulation of transcription, DNA-templated; GO:0022409 positive regulation of cell-cell adhesion; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0022407 regulation of cell-cell adhesion; GO:0043085 positive regulation of catalytic activity; GO:0048736 appendage development; GO:0034330 cell junction organization; GO:0031589 cell-substrate adhesion; GO:0044767 single-organism developmental process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0040012 regulation of locomotion; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016323 basolateral plasma membrane; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0098636 protein complex involved in cell adhesion; GO:0009897 external side of plasma membrane; GO:0098796 membrane protein complex; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0005887 integral component of plasma membrane; GO:0005913 cell-cell adherens junction; GO:0098858 actin-based cell projection; GO:0005911 cell-cell junction; GO:0005623 cell; GO:0044420 extracellular matrix component; GO:0034676 integrin alpha6-beta4 complex; GO:0005604 basement membrane; GO:0005925 focal adhesion; GO:0098590 plasma membrane region; GO:0044464 cell part; GO:0044425 membrane part; GO:0005912 adherens junction; GO:0030175 filopodium; GO:0030055 cell-substrate junction; GO:0030056 hemidesmosome; GO:0005924 cell-substrate adherens junction; GO:0098552 side of membrane; GO:0042995 cell projection; GO:0031226 intrinsic component of plasma membrane; GO:0098802 plasma membrane receptor complex; GO:0098797 plasma membrane protein complex; GO:0070161 anchoring junction; GO:0043235 receptor complex; GO:0008305 integrin complex; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0031012 extracellular matrix; GO:0044459 plasma membrane part; GO:0009925 basal plasma membrane; GO:0005578 proteinaceous extracellular matrix; GO:0009986 cell surface; GO:0043234 protein complex; GO:0045178 basal part of cell; ","GO:0050839 cell adhesion molecule binding; GO:0043236 laminin binding; GO:0005102 receptor binding; GO:0005488 binding; GO:0043167 ion binding; GO:0045296 cadherin binding; GO:0044877 macromolecular complex binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0005178 integrin binding; GO:0050840 extracellular matrix binding; GO:0032403 protein complex binding; ","K06485","ITGA6; integrin alpha 6","hsa05200 Pathways in cancer - Homo sapiens (human); hsa05414 Dilated cardiomyopathy (DCM) - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa04640 Hematopoietic cell lineage - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa05222 Small cell lung cancer - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa04512 ECM-receptor interaction - Homo sapiens (human); hsa05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human); hsa04514 Cell adhesion molecules (CAMs) - Homo sapiens (human); hsa05410 Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human); hsa05145 Toxoplasmosis - Homo sapiens (human); ","IPR032695; IPR013649; ","Integrin domain; Integrin alpha-2; \r"]
["P23297","Protein S100-A1 OS=Homo sapiens OX=9606 GN=S100A1","S100A1",10.546,21.467,45.7,3,6,3,1.121,1.144,1.203,0.861,0.825,0.803,0.718,0.000341,"cytoplasm\r","GO:0044700 single organism signaling; GO:0007420 brain development; GO:0044699 single-organism process; GO:0031347 regulation of defense response; GO:1904427 positive regulation of calcium ion transmembrane transport; GO:0051253 negative regulation of RNA metabolic process; GO:0048857 neural nucleus development; GO:0021762 substantia nigra development; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0045088 regulation of innate immune response; GO:0032879 regulation of localization; GO:1901019 regulation of calcium ion transmembrane transporter activity; GO:0044093 positive regulation of molecular function; GO:0032414 positive regulation of ion transmembrane transporter activity; GO:0044057 regulation of system process; GO:0002221 pattern recognition receptor signaling pathway; GO:0060322 head development; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:1901385 regulation of voltage-gated calcium channel activity; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0010468 regulation of gene expression; GO:0030901 midbrain development; GO:0031326 regulation of cellular biosynthetic process; GO:0002758 innate immune response-activating signal transduction; GO:0080090 regulation of primary metabolic process; GO:0043269 regulation of ion transport; GO:0000122 negative regulation of transcription from RNA polymerase II promoter; GO:0022898 regulation of transmembrane transporter activity; GO:0002764 immune response-regulating signaling pathway; GO:0031323 regulation of cellular metabolic process; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0050776 regulation of immune response; GO:0051050 positive regulation of transport; GO:0034762 regulation of transmembrane transport; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0034767 positive regulation of ion transmembrane transport; GO:0002224 toll-like receptor signaling pathway; GO:0007417 central nervous system development; GO:0048583 regulation of response to stimulus; GO:1902679 negative regulation of RNA biosynthetic process; GO:2001257 regulation of cation channel activity; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0002682 regulation of immune system process; GO:1901021 positive regulation of calcium ion transmembrane transporter activity; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0032412 regulation of ion transmembrane transporter activity; GO:0048856 anatomical structure development; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0002218 activation of innate immune response; GO:0034764 positive regulation of transmembrane transport; GO:0032411 positive regulation of transporter activity; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:1903522 regulation of blood circulation; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0008016 regulation of heart contraction; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:0045892 negative regulation of transcription, DNA-templated; GO:1901387 positive regulation of voltage-gated calcium channel activity; GO:0031349 positive regulation of defense response; GO:0009889 regulation of biosynthetic process; GO:1903169 regulation of calcium ion transmembrane transport; GO:0002757 immune response-activating signal transduction; GO:0010959 regulation of metal ion transport; GO:0051171 regulation of nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0050778 positive regulation of immune response; GO:0009987 cellular process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0032409 regulation of transporter activity; GO:1904062 regulation of cation transmembrane transport; GO:0051928 positive regulation of calcium ion transport; GO:0002253 activation of immune response; GO:0045089 positive regulation of innate immune response; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0035556 intracellular signal transduction; GO:0048731 system development; GO:0051049 regulation of transport; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0051924 regulation of calcium ion transport; GO:0002376 immune system process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0009892 negative regulation of metabolic process; GO:0048518 positive regulation of biological process; GO:2001259 positive regulation of cation channel activity; GO:0043270 positive regulation of ion transport; GO:0009890 negative regulation of biosynthetic process; GO:0034765 regulation of ion transmembrane transport; GO:1904064 positive regulation of cation transmembrane transport; GO:0044767 single-organism developmental process; GO:0002684 positive regulation of immune system process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0048584 positive regulation of response to stimulus; GO:0065007 biological regulation; ","GO:0005783 endoplasmic reticulum; GO:0030016 myofibril; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0030018 Z disc; GO:0099080 supramolecular complex; GO:0016528 sarcoplasm; GO:0005623 cell; GO:0031674 I band; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005622 intracellular; GO:0044464 cell part; GO:0043292 contractile fiber; GO:0043005 neuron projection; GO:0031430 M band; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0016529 sarcoplasmic reticulum; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0099081 supramolecular polymer; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0031672 A band; GO:0030017 sarcomere; GO:0044449 contractile fiber part; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0042802 identical protein binding; GO:0051117 ATPase binding; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0043167 ion binding; GO:0046983 protein dimerization activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0044548 S100 protein binding; GO:0005515 protein binding; GO:0005509 calcium ion binding; GO:0048306 calcium-dependent protein binding; GO:0019899 enzyme binding; ",{"$nulls":3},"IPR002048; IPR011992; IPR013787; ","\"EF-hand domain; EF-hand domain pair; S100/CaBP-9k-type, calcium binding, subdomain; \"\r"]
["P23368","NAD-dependent malic enzyme, mitochondrial OS=Homo sapiens OX=9606 GN=ME2","ME2",65.443,43.789,14.6,7,8,6,0.98,1.067,1.008,1,1.005,0.953,0.968,0.35,"mitochondria\r","GO:0050794 regulation of cellular process; GO:0051193 regulation of cofactor metabolic process; GO:0043648 dicarboxylic acid metabolic process; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0031323 regulation of cellular metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0051196 regulation of coenzyme metabolic process; GO:1902031 regulation of NADP metabolic process; GO:0006090 pyruvate metabolic process; GO:0008152 metabolic process; GO:0050789 regulation of biological process; GO:0044710 single-organism metabolic process; GO:0006108 malate metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0006082 organic acid metabolic process; GO:0009987 cellular process; GO:0043436 oxoacid metabolic process; GO:0006140 regulation of nucleotide metabolic process; GO:0065007 biological regulation; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity; GO:1901265 nucleoside phosphate binding; GO:0043167 ion binding; GO:0008948 oxaloacetate decarboxylase activity; GO:0016829 lyase activity; GO:0000166 nucleotide binding; GO:0048037 cofactor binding; GO:0016491 oxidoreductase activity; GO:0009055 electron carrier activity; GO:0016614 oxidoreductase activity, acting on CH-OH group of donors; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; GO:0003824 catalytic activity; GO:0051287 NAD binding; GO:0016830 carbon-carbon lyase activity; GO:0005488 binding; GO:0004473 malate dehydrogenase (decarboxylating) (NADP+) activity; GO:0016831 carboxy-lyase activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0016615 malate dehydrogenase activity; GO:0004470 malic enzyme activity; GO:0036094 small molecule binding; GO:0050662 coenzyme binding; ","K00027","ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38]","hsa00620 Pyruvate metabolism - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); ","IPR012302; IPR012301; IPR016040; ","\"Malic enzyme, NAD-binding; Malic enzyme, N-terminal domain; NAD(P)-binding domain; \"\r"]
["P23434","Glycine cleavage system H protein, mitochondrial OS=Homo sapiens OX=9606 GN=GCSH","GCSH",18.884,27.764,17.3,2,4,2,1.218,1.231,1.098,0.788,0.893,0.806,0.701,0.00258,"mitochondria\r","GO:1901606 alpha-amino acid catabolic process; GO:0019464 glycine decarboxylation via glycine cleavage system; GO:0044699 single-organism process; GO:0006544 glycine metabolic process; GO:0044237 cellular metabolic process; GO:0032259 methylation; GO:0071704 organic substance metabolic process; GO:0006546 glycine catabolic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0044248 cellular catabolic process; GO:0046487 glyoxylate metabolic process; GO:0009987 cellular process; GO:0044712 single-organism catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006081 cellular aldehyde metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044282 small molecule catabolic process; GO:0044238 primary metabolic process; GO:1901605 alpha-amino acid metabolic process; GO:0046395 carboxylic acid catabolic process; GO:1901575 organic substance catabolic process; GO:1901565 organonitrogen compound catabolic process; GO:0009071 serine family amino acid catabolic process; GO:0009069 serine family amino acid metabolic process; GO:0044710 single-organism metabolic process; GO:0016054 organic acid catabolic process; GO:0019752 carboxylic acid metabolic process; GO:0009063 cellular amino acid catabolic process; GO:0006082 organic acid metabolic process; GO:0009056 catabolic process; GO:0043436 oxoacid metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0005960 glycine cleavage complex; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:1990204 oxidoreductase complex; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0008168 methyltransferase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016741 transferase activity, transferring one-carbon groups; GO:0005515 protein binding; GO:0004047 aminomethyltransferase activity; GO:0016740 transferase activity; ","K02437","gcvH; glycine cleavage system H protein","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00260 Glycine, serine and threonine metabolism - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); hsa00630 Glyoxylate and dicarboxylate metabolism - Homo sapiens (human); ","IPR011053; IPR000089; ","Single hybrid motif; Biotin/lipoyl attachment; \r"]
["P23497","Nuclear autoantigen Sp-100 OS=Homo sapiens OX=9606 GN=SP100","SP100",100.42,16.231,5,5,7,4,0.82,0.919,0.883,1.211,1.043,1.119,1.286,0.01,"nucleus\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0010941 regulation of cell death; GO:0007166 cell surface receptor signaling pathway; GO:0097659 nucleic acid-templated transcription; GO:0009891 positive regulation of biosynthetic process; GO:0090317 negative regulation of intracellular protein transport; GO:0044237 cellular metabolic process; GO:0032897 negative regulation of viral transcription; GO:0071345 cellular response to cytokine stimulus; GO:0042772 DNA damage response, signal transduction resulting in transcription; GO:0010594 regulation of endothelial cell migration; GO:0008152 metabolic process; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0030522 intracellular receptor signaling pathway; GO:0043392 negative regulation of DNA binding; GO:0043170 macromolecule metabolic process; GO:0032387 negative regulation of intracellular transport; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0008104 protein localization; GO:0044419 interspecies interaction between organisms; GO:0046823 negative regulation of nucleocytoplasmic transport; GO:0051051 negative regulation of transport; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0010632 regulation of epithelial cell migration; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0000122 negative regulation of transcription from RNA polymerase II promoter; GO:0034340 response to type I interferon; GO:0032774 RNA biosynthetic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:2000146 negative regulation of cell motility; GO:0031323 regulation of cellular metabolic process; GO:0051704 multi-organism process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048384 retinoic acid receptor signaling pathway; GO:0046825 regulation of protein export from nucleus; GO:0032526 response to retinoic acid; GO:1902044 regulation of Fas signaling pathway; GO:0051090 regulation of sequence-specific DNA binding transcription factor activity; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0045765 regulation of angiogenesis; GO:0051223 regulation of protein transport; GO:0032200 telomere organization; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0006259 DNA metabolic process; GO:1901700 response to oxygen-containing compound; GO:0043067 regulation of programmed cell death; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0060249 anatomical structure homeostasis; GO:0051239 regulation of multicellular organismal process; GO:0060341 regulation of cellular localization; GO:1903901 negative regulation of viral life cycle; GO:0030330 DNA damage response, signal transduction by p53 class mediator; GO:0045892 negative regulation of transcription, DNA-templated; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:2000145 regulation of cell motility; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0032880 regulation of protein localization; GO:0071357 cellular response to type I interferon; GO:0009966 regulation of signal transduction; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0051254 positive regulation of RNA metabolic process; GO:0006950 response to stress; GO:0051270 regulation of cellular component movement; GO:0051224 negative regulation of protein transport; GO:0072331 signal transduction by p53 class mediator; GO:0043900 regulation of multi-organism process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0030334 regulation of cell migration; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0006974 cellular response to DNA damage stimulus; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0046782 regulation of viral transcription; GO:0009890 negative regulation of biosynthetic process; GO:0010596 negative regulation of endothelial cell migration; GO:0051276 chromosome organization; GO:0046822 regulation of nucleocytoplasmic transport; GO:0030336 negative regulation of cell migration; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0051179 localization; GO:0006955 immune response; GO:0050793 regulation of developmental process; GO:1903827 regulation of cellular protein localization; GO:0000723 telomere maintenance; GO:0001101 response to acid chemical; GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity; GO:0010633 negative regulation of epithelial cell migration; GO:0023051 regulation of signaling; GO:0071346 cellular response to interferon-gamma; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0051253 negative regulation of RNA metabolic process; GO:0040013 negative regulation of locomotion; GO:0060333 interferon-gamma-mediated signaling pathway; GO:2001141 regulation of RNA biosynthetic process; GO:2001233 regulation of apoptotic signaling pathway; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0033036 macromolecule localization; GO:0070887 cellular response to chemical stimulus; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0048525 negative regulation of viral process; GO:0010468 regulation of gene expression; GO:1903828 negative regulation of cellular protein localization; GO:0031326 regulation of cellular biosynthetic process; GO:0034097 response to cytokine; GO:0051098 regulation of binding; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity; GO:0032386 regulation of intracellular transport; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0016070 RNA metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0051100 negative regulation of binding; GO:1902679 negative regulation of RNA biosynthetic process; GO:2001236 regulation of extrinsic apoptotic signaling pathway; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0006952 defense response; GO:2000026 regulation of multicellular organismal development; GO:0051271 negative regulation of cellular component movement; GO:0016043 cellular component organization; GO:0060337 type I interferon signaling pathway; GO:0006725 cellular aromatic compound metabolic process; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0071310 cellular response to organic substance; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0051101 regulation of DNA binding; GO:0045087 innate immune response; GO:0070201 regulation of establishment of protein localization; GO:0046826 negative regulation of protein export from nucleus; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0033993 response to lipid; GO:0016032 viral process; GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors; GO:0042770 signal transduction in response to DNA damage; GO:0034641 cellular nitrogen compound metabolic process; GO:0051235 maintenance of location; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0019221 cytokine-mediated signaling pathway; GO:0033157 regulation of intracellular protein transport; GO:0006355 regulation of transcription, DNA-templated; GO:0045185 maintenance of protein location; GO:0035556 intracellular signal transduction; GO:0010629 negative regulation of gene expression; GO:0051049 regulation of transport; GO:1901342 regulation of vasculature development; GO:0050792 regulation of viral process; GO:0006807 nitrogen compound metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0034341 response to interferon-gamma; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0043901 negative regulation of multi-organism process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0010467 gene expression; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:1904950 negative regulation of establishment of protein localization; GO:0031327 negative regulation of cellular biosynthetic process; GO:0040012 regulation of locomotion; GO:1903900 regulation of viral life cycle; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0000784 nuclear chromosome, telomeric region; GO:0000781 chromosome, telomeric region; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005730 nucleolus; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0098687 chromosomal region; GO:0043226 organelle; GO:0016605 PML body; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044454 nuclear chromosome part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0000228 nuclear chromosome; GO:0034399 nuclear periphery; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0070087 chromo shadow domain binding; GO:0003677 DNA binding; GO:0003714 transcription corepressor activity; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:0019900 kinase binding; GO:0003712 transcription cofactor activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0042802 identical protein binding; GO:0005488 binding; GO:0042803 protein homodimerization activity; GO:0003676 nucleic acid binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0003713 transcription coactivator activity; GO:0019904 protein domain specific binding; GO:0000988 transcription factor activity, protein binding; GO:0008134 transcription factor binding; GO:0019899 enzyme binding; ","K15413","SP100; nuclear autoantigen Sp-100","hsa05168 Herpes simplex infection - Homo sapiens (human); hsa05203 Viral carcinogenesis - Homo sapiens (human); ","IPR004865; IPR009071; IPR010919; IPR000770; ","HSR domain; High mobility group box domain; SAND domain-like; SAND domain; \r"]
["P23588","Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B","EIF4B",69.15,47.835,18,10,11,10,0.875,0.911,0.884,1.041,1.05,1.139,1.21,0.00366,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0006518 peptide metabolic process; GO:0022618 ribonucleoprotein complex assembly; GO:0010608 posttranscriptional regulation of gene expression; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0071826 ribonucleoprotein complex subunit organization; GO:0002181 cytoplasmic translation; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0006413 translational initiation; GO:1901361 organic cyclic compound catabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0006412 translation; GO:0002183 cytoplasmic translational initiation; GO:0010468 regulation of gene expression; GO:0071822 protein complex subunit organization; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0043043 peptide biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0006401 RNA catabolic process; GO:0016070 RNA metabolic process; GO:0019439 aromatic compound catabolic process; GO:1901575 organic substance catabolic process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0070271 protein complex biogenesis; GO:0016071 mRNA metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0044267 cellular protein metabolic process; GO:0048519 negative regulation of biological process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0043623 cellular protein complex assembly; GO:0034622 cellular macromolecular complex assembly; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0034248 regulation of cellular amide metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0097010 eukaryotic translation initiation factor 4F complex assembly; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0051246 regulation of protein metabolic process; GO:0006417 regulation of translation; GO:0001731 formation of translation preinitiation complex; GO:0009057 macromolecule catabolic process; GO:0006446 regulation of translational initiation; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0009056 catabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:1990904 ribonucleoprotein complex; GO:0043234 protein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0005829 cytosol; GO:0005623 cell; GO:0044444 cytoplasmic part; GO:0016281 eukaryotic translation initiation factor 4F complex; GO:0005844 polysome; ","GO:0003723 RNA binding; GO:1901265 nucleoside phosphate binding; GO:0097617 annealing activity; GO:0004386 helicase activity; GO:0003725 double-stranded RNA binding; GO:0044877 macromolecular complex binding; GO:0003743 translation initiation factor activity; GO:0034057 RNA strand-exchange activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0003727 single-stranded RNA binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0008135 translation factor activity, RNA binding; GO:0016462 pyrophosphatase activity; GO:0043024 ribosomal small subunit binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0033592 RNA strand annealing activity; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0043021 ribonucleoprotein complex binding; GO:0036094 small molecule binding; ","K03258","EIF4B; translation initiation factor 4B","hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa03013 RNA transport - Homo sapiens (human); hsa04150 mTOR signaling pathway - Homo sapiens (human); ","IPR000504; IPR012677; ","RNA recognition motif domain; Nucleotide-binding alpha-beta plait domain; \r"]
["P23610","Factor VIII intron 22 protein OS=Homo sapiens OX=9606 GN=F8A1","F8A1",39.103,21.247,3.8,1,1,1,0.935,0.967,1.111,0.998,1.083,0.911,0.993,0.931,"cytoplasm\r",null,"GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; ","GO:0005515 protein binding; GO:0005488 binding; ","K20135",null,null,"IPR011990; ","Tetratricopeptide-like helical domain; \r"]
["P23919","Thymidylate kinase OS=Homo sapiens OX=9606 GN=DTYMK","DTYMK",23.819,7.9999,13.7,3,3,3,0.924,1.023,1.135,0.992,0.869,1.064,0.949,0.567,"cytoplasm\r","GO:0046077 dUDP metabolic process; GO:0009147 pyrimidine nucleoside triphosphate metabolic process; GO:0043627 response to estrogen; GO:0048869 cellular developmental process; GO:0009117 nucleotide metabolic process; GO:0045445 myoblast differentiation; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0046939 nucleotide phosphorylation; GO:0071363 cellular response to growth factor stimulus; GO:0009262 deoxyribonucleotide metabolic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0009263 deoxyribonucleotide biosynthetic process; GO:0008152 metabolic process; GO:0019692 deoxyribose phosphate metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0006753 nucleoside phosphate metabolic process; GO:0046686 response to cadmium ion; GO:0072527 pyrimidine-containing compound metabolic process; GO:0070848 response to growth factor; GO:0010035 response to inorganic substance; GO:0009186 deoxyribonucleoside diphosphate metabolic process; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0046940 nucleoside monophosphate phosphorylation; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0010038 response to metal ion; GO:0009219 pyrimidine deoxyribonucleotide metabolic process; GO:0046075 dTTP metabolic process; GO:0090407 organophosphate biosynthetic process; GO:0042221 response to chemical; GO:0006227 dUDP biosynthetic process; GO:0009197 pyrimidine deoxyribonucleoside diphosphate biosynthetic process; GO:0044710 single-organism metabolic process; GO:0046072 dTDP metabolic process; GO:0006235 dTTP biosynthetic process; GO:0048856 anatomical structure development; GO:1901362 organic cyclic compound biosynthetic process; GO:0016310 phosphorylation; GO:0009202 deoxyribonucleoside triphosphate biosynthetic process; GO:0009165 nucleotide biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0015949 nucleobase-containing small molecule interconversion; GO:0009142 nucleoside triphosphate biosynthetic process; GO:0071310 cellular response to organic substance; GO:0009139 pyrimidine nucleoside diphosphate biosynthetic process; GO:0009200 deoxyribonucleoside triphosphate metabolic process; GO:0006221 pyrimidine nucleotide biosynthetic process; GO:0009138 pyrimidine nucleoside diphosphate metabolic process; GO:0050896 response to stimulus; GO:0009394 2'-deoxyribonucleotide metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0072528 pyrimidine-containing compound biosynthetic process; GO:0030154 cell differentiation; GO:0009196 pyrimidine deoxyribonucleoside diphosphate metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process; GO:0009189 deoxyribonucleoside diphosphate biosynthetic process; GO:0009221 pyrimidine deoxyribonucleotide biosynthetic process; GO:1901135 carbohydrate derivative metabolic process; GO:0009265 2'-deoxyribonucleotide biosynthetic process; GO:0061061 muscle structure development; GO:0034641 cellular nitrogen compound metabolic process; GO:0009212 pyrimidine deoxyribonucleoside triphosphate biosynthetic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0009132 nucleoside diphosphate metabolic process; GO:0044711 single-organism biosynthetic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0009148 pyrimidine nucleoside triphosphate biosynthetic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0008283 cell proliferation; GO:0009133 nucleoside diphosphate biosynthetic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0006220 pyrimidine nucleotide metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0044767 single-organism developmental process; GO:0019637 organophosphate metabolic process; GO:0042692 muscle cell differentiation; GO:0046385 deoxyribose phosphate biosynthetic process; GO:0006233 dTDP biosynthetic process; GO:0007049 cell cycle; GO:1901564 organonitrogen compound metabolic process; GO:0009123 nucleoside monophosphate metabolic process; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0031967 organelle envelope; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031970 organelle envelope lumen; GO:0070013 intracellular organelle lumen; GO:0005758 mitochondrial intermembrane space; GO:0044464 cell part; GO:0005622 intracellular; GO:0031975 envelope; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0019205 nucleobase-containing compound kinase activity; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0009041 uridylate kinase activity; GO:0000166 nucleotide binding; GO:0016776 phosphotransferase activity, phosphate group as acceptor; GO:0019201 nucleotide kinase activity; GO:0004798 thymidylate kinase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0050145 nucleoside phosphate kinase activity; GO:0097367 carbohydrate derivative binding; GO:0016301 kinase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0016740 transferase activity; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K00943","tmk; dTMP kinase [EC:2.7.4.9]","hsa00240 Pyrimidine metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR027417; ","P-loop containing nucleoside triphosphate hydrolase; \r"]
["P23921","Ribonucleoside-diphosphate reductase large subunit OS=Homo sapiens OX=9606 GN=RRM1","RRM1",90.069,12.148,4.7,4,6,4,0.745,0.649,0.655,1.266,1.394,1.258,1.912,0.000303,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0022414 reproductive process; GO:0007420 brain development; GO:0009117 nucleotide metabolic process; GO:0008584 male gonad development; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0009262 deoxyribonucleotide metabolic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0009263 deoxyribonucleotide biosynthetic process; GO:0061351 neural precursor cell proliferation; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0051262 protein tetramerization; GO:0022607 cellular component assembly; GO:0051290 protein heterotetramerization; GO:0006753 nucleoside phosphate metabolic process; GO:0065003 macromolecular complex assembly; GO:0044702 single organism reproductive process; GO:0072527 pyrimidine-containing compound metabolic process; GO:0060322 head development; GO:0009314 response to radiation; GO:0043170 macromolecule metabolic process; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0000278 mitotic cell cycle; GO:0018130 heterocycle biosynthetic process; GO:0003006 developmental process involved in reproduction; GO:0071822 protein complex subunit organization; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0048608 reproductive structure development; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0006206 pyrimidine nucleobase metabolic process; GO:0032501 multicellular organismal process; GO:0051291 protein heterooligomerization; GO:0090407 organophosphate biosynthetic process; GO:0048513 animal organ development; GO:0090304 nucleic acid metabolic process; GO:0007417 central nervous system development; GO:0044710 single-organism metabolic process; GO:0021846 cell proliferation in forebrain; GO:0044260 cellular macromolecule metabolic process; GO:0009112 nucleobase metabolic process; GO:0070271 protein complex biogenesis; GO:0048856 anatomical structure development; GO:1901362 organic cyclic compound biosynthetic process; GO:0000003 reproduction; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0043010 camera-type eye development; GO:0009165 nucleotide biosynthetic process; GO:0006260 DNA replication; GO:0006725 cellular aromatic compound metabolic process; GO:0009628 response to abiotic stimulus; GO:0006259 DNA metabolic process; GO:0015949 nucleobase-containing small molecule interconversion; GO:0046661 male sex differentiation; GO:0008406 gonad development; GO:0050896 response to stimulus; GO:0051259 protein oligomerization; GO:0071704 organic substance metabolic process; GO:0001654 eye development; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0007548 sex differentiation; GO:0030900 forebrain development; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0009059 macromolecule biosynthetic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0061458 reproductive system development; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0045137 development of primary sexual characteristics; GO:0060041 retina development in camera-type eye; GO:0044711 single-organism biosynthetic process; GO:0048731 system development; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0008283 cell proliferation; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0010212 response to ionizing radiation; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0044767 single-organism developmental process; GO:0019637 organophosphate metabolic process; GO:0046546 development of primary male sexual characteristics; GO:0007423 sensory organ development; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:1901564 organonitrogen compound metabolic process; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0042995 cell projection; GO:0005635 nuclear envelope; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0043025 neuronal cell body; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0031975 envelope; GO:1903561 extracellular vesicle; GO:0044297 cell body; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0016725 oxidoreductase activity, acting on CH or CH2 groups; GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0061731 ribonucleoside-diphosphate reductase activity; GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0016491 oxidoreductase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0016728 oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K10807","RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]","hsa00230 Purine metabolism - Homo sapiens (human); hsa00480 Glutathione metabolism - Homo sapiens (human); hsa00983 Drug metabolism - other enzymes - Homo sapiens (human); hsa00240 Pyrimidine metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR000788; IPR013346; IPR013509; IPR005144; IPR008926; ","\"Ribonucleotide reductase large subunit, C-terminal; Ribonucleotide reductase, class I , alpha subunit; Ribonucleotide reductase large subunit, N-terminal; ATP-cone domain; Ribonucleotide reductase R1 subunit, N-terminal; \"\r"]
["P24043","Laminin subunit alpha-2 OS=Homo sapiens OX=9606 GN=LAMA2","LAMA2",343.9,10.94,1,3,3,3,0.964,1.067,1.058,1.099,0.962,0.868,0.948,0.494,"extracellular\r","GO:0048666 neuron development; GO:0023051 regulation of signaling; GO:0048869 cellular developmental process; GO:0014037 Schwann cell differentiation; GO:0032989 cellular component morphogenesis; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0022610 biological adhesion; GO:0009605 response to external stimulus; GO:0050806 positive regulation of synaptic transmission; GO:0010646 regulation of cell communication; GO:0032990 cell part morphogenesis; GO:0032879 regulation of localization; GO:0007155 cell adhesion; GO:0048858 cell projection morphogenesis; GO:0030198 extracellular matrix organization; GO:0007422 peripheral nervous system development; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0048812 neuron projection morphogenesis; GO:0006935 chemotaxis; GO:0032501 multicellular organismal process; GO:0032224 positive regulation of synaptic transmission, cholinergic; GO:0000902 cell morphogenesis; GO:0048513 animal organ development; GO:0042221 response to chemical; GO:0042063 gliogenesis; GO:0050789 regulation of biological process; GO:0007517 muscle organ development; GO:0030030 cell projection organization; GO:0032222 regulation of synaptic transmission, cholinergic; GO:0042330 taxis; GO:0040011 locomotion; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:0048468 cell development; GO:0007411 axon guidance; GO:0000904 cell morphogenesis involved in differentiation; GO:0009653 anatomical structure morphogenesis; GO:0030154 cell differentiation; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0043062 extracellular structure organization; GO:2000145 regulation of cell motility; GO:0023056 positive regulation of signaling; GO:0007409 axonogenesis; GO:0061061 muscle structure development; GO:0007275 multicellular organism development; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0050804 modulation of synaptic transmission; GO:0030334 regulation of cell migration; GO:0031175 neuron projection development; GO:0048518 positive regulation of biological process; GO:0030155 regulation of cell adhesion; GO:0010001 glial cell differentiation; GO:0061564 axon development; GO:0030182 neuron differentiation; GO:0045995 regulation of embryonic development; GO:0097485 neuron projection guidance; GO:0044767 single-organism developmental process; GO:0006928 movement of cell or subcellular component; GO:0040012 regulation of locomotion; GO:0050793 regulation of developmental process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0030425 dendrite; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005623 cell; GO:0044420 extracellular matrix component; GO:0043197 dendritic spine; GO:0005604 basement membrane; GO:0005605 basal lamina; GO:0070062 extracellular exosome; GO:0044309 neuron spine; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0044456 synapse part; GO:0042995 cell projection; GO:0044463 cell projection part; GO:0005576 extracellular region; GO:0045202 synapse; GO:0005886 plasma membrane; GO:0031012 extracellular matrix; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0098794 postsynapse; GO:0005578 proteinaceous extracellular matrix; GO:0042383 sarcolemma; GO:0043230 extracellular organelle; ","GO:0005515 protein binding; GO:0005198 structural molecule activity; GO:0005102 receptor binding; GO:0005488 binding; ","K05637","LAMA1_2; laminin, alpha 1/2","hsa05200 Pathways in cancer - Homo sapiens (human); hsa05414 Dilated cardiomyopathy (DCM) - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa05416 Viral myocarditis - Homo sapiens (human); hsa05146 Amoebiasis - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa05222 Small cell lung cancer - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa04512 ECM-receptor interaction - Homo sapiens (human); hsa05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human); hsa05410 Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human); hsa05145 Toxoplasmosis - Homo sapiens (human); ","IPR000034; IPR009254; IPR002049; IPR000742; IPR008211; IPR010307; IPR001791; IPR013320; IPR008979; ","\"Laminin IV; Laminin alpha, domain I; Laminin EGF domain; EGF-like domain; Laminin, N-terminal; Laminin domain II; Laminin G domain; Concanavalin A-like lectin/glucanase domain; Galactose-binding domain-like; \"\r"]
["P24310","Cytochrome c oxidase subunit 7A1, mitochondrial OS=Homo sapiens OX=9606 GN=COX7A1","COX7A1",9.1174,12.298,16.5,1,2,1,1.27,1.173,1.206,0.719,0.816,0.848,0.653,1.48E-3,"mitochondria\r","GO:0098655 cation transmembrane transport; GO:0034220 ion transmembrane transport; GO:0098660 inorganic ion transmembrane transport; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0015992 proton transport; GO:0006818 hydrogen transport; GO:0051234 establishment of localization; GO:0006810 transport; GO:0055085 transmembrane transport; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:1902578 single-organism localization; GO:0006812 cation transport; GO:0006811 ion transport; GO:1902600 hydrogen ion transmembrane transport; GO:0051179 localization; GO:0015672 monovalent inorganic cation transport; GO:0009987 cellular process; GO:0098662 inorganic cation transmembrane transport; GO:0044765 single-organism transport; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044429 mitochondrial part; GO:0031090 organelle membrane; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0005746 mitochondrial respiratory chain; GO:0005740 mitochondrial envelope; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0031975 envelope; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0070469 respiratory chain; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0015075 ion transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0015077 monovalent inorganic cation transmembrane transporter activity; GO:0016676 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor; GO:0016675 oxidoreductase activity, acting on a heme group of donors; GO:0015078 hydrogen ion transmembrane transporter activity; GO:0015002 heme-copper terminal oxidase activity; GO:0016491 oxidoreductase activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0009055 electron carrier activity; GO:0004129 cytochrome-c oxidase activity; GO:0003824 catalytic activity; GO:0022890 inorganic cation transmembrane transporter activity; GO:0008324 cation transmembrane transporter activity; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; ","K02270","COX7A; cytochrome c oxidase subunit 7a","hsa04260 Cardiac muscle contraction - Homo sapiens (human); hsa05010 Alzheimer's disease - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); "]
["P24534","Elongation factor 1-beta OS=Homo sapiens OX=9606 GN=EEF1B2","EEF1B2",24.763,63.972,39.1,8,26,6,0.831,0.859,0.89,1.15,1.166,1.151,1.344,0.000124,"nucleus\r","GO:0006518 peptide metabolic process; GO:0045471 response to ethanol; GO:1901700 response to oxygen-containing compound; GO:0044267 cellular protein metabolic process; GO:0009058 biosynthetic process; GO:0050896 response to stimulus; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006412 translation; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006414 translational elongation; GO:0043043 peptide biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0097305 response to alcohol; GO:0043603 cellular amide metabolic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0042221 response to chemical; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0043234 protein complex; GO:0005623 cell; GO:0005829 cytosol; GO:0005853 eukaryotic translation elongation factor 1 complex; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0008135 translation factor activity, RNA binding; GO:0003746 translation elongation factor activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; ","K03232",null,null,"IPR014717; IPR014038; IPR010987; IPR018940; ","\"Translation elongation factor EF1B/ribosomal protein S6; Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain; Glutathione S-transferase, C-terminal-like; Elongation factor 1 beta central acidic region, eukaryote; \"\r"]
["P24593","Insulin-like growth factor-binding protein 5 OS=Homo sapiens OX=9606 GN=IGFBP5","IGFBP5",30.57,13.616,16.5,5,7,5,1.119,1.019,1.139,0.864,0.858,0.977,0.824,0.0234,"extracellular\r","GO:0044700 single organism signaling; GO:0001649 osteoblast differentiation; GO:0065008 regulation of biological quality; GO:0048732 gland development; GO:0051896 regulation of protein kinase B signaling; GO:0014745 negative regulation of muscle adaptation; GO:0022414 reproductive process; GO:0030323 respiratory tube development; GO:0010608 posttranscriptional regulation of gene expression; GO:0042593 glucose homeostasis; GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway; GO:0046683 response to organophosphorus; GO:1901862 negative regulation of muscle tissue development; GO:0044237 cellular metabolic process; GO:0008285 negative regulation of cell proliferation; GO:0006006 glucose metabolic process; GO:0001558 regulation of cell growth; GO:0008152 metabolic process; GO:0014743 regulation of muscle hypertrophy; GO:0032879 regulation of localization; GO:0044706 multi-multicellular organism process; GO:0009719 response to endogenous stimulus; GO:0008544 epidermis development; GO:0044057 regulation of system process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:1901652 response to peptide; GO:0045667 regulation of osteoblast differentiation; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0043588 skin development; GO:0080090 regulation of primary metabolic process; GO:0001503 ossification; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0034249 negative regulation of cellular amide metabolic process; GO:2000146 negative regulation of cell motility; GO:0005975 carbohydrate metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0050673 epithelial cell proliferation; GO:0098773 skin epidermis development; GO:0010243 response to organonitrogen compound; GO:0048513 animal organ development; GO:0051591 response to cAMP; GO:0044710 single-organism metabolic process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0044260 cellular macromolecule metabolic process; GO:0009887 animal organ morphogenesis; GO:0014912 negative regulation of smooth muscle cell migration; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0001942 hair follicle development; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0000003 reproduction; GO:0050794 regulation of cellular process; GO:0002009 morphogenesis of an epithelium; GO:0044707 single-multicellular organism process; GO:0042127 regulation of cell proliferation; GO:0042303 molting cycle; GO:1901700 response to oxygen-containing compound; GO:0044267 cellular protein metabolic process; GO:0017148 negative regulation of translation; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0010906 regulation of glucose metabolic process; GO:0051239 regulation of multicellular organismal process; GO:0030879 mammary gland development; GO:0009653 anatomical structure morphogenesis; GO:0007565 female pregnancy; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0060541 respiratory system development; GO:2000145 regulation of cell motility; GO:0014074 response to purine-containing compound; GO:0009889 regulation of biosynthetic process; GO:0061061 muscle structure development; GO:0051171 regulation of nitrogen compound metabolic process; GO:0033500 carbohydrate homeostasis; GO:0060443 mammary gland morphogenesis; GO:0007275 multicellular organism development; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0009966 regulation of signal transduction; GO:0048878 chemical homeostasis; GO:1902531 regulation of intracellular signal transduction; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0030334 regulation of cell migration; GO:0071407 cellular response to organic cyclic compound; GO:0008283 cell proliferation; GO:0010033 response to organic substance; GO:0022405 hair cycle process; GO:0006109 regulation of carbohydrate metabolic process; GO:0044238 primary metabolic process; GO:0042633 hair cycle; GO:0009892 negative regulation of metabolic process; GO:0034248 regulation of cellular amide metabolic process; GO:0009890 negative regulation of biosynthetic process; GO:0043502 regulation of muscle adaptation; GO:0030336 negative regulation of cell migration; GO:0030278 regulation of ossification; GO:0048584 positive regulation of response to stimulus; GO:0048286 lung alveolus development; GO:0050793 regulation of developmental process; GO:0019318 hexose metabolic process; GO:0051093 negative regulation of developmental process; GO:0043567 regulation of insulin-like growth factor receptor signaling pathway; GO:0009968 negative regulation of signal transduction; GO:1904205 negative regulation of skeletal muscle hypertrophy; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0051241 negative regulation of multicellular organismal process; GO:0045668 negative regulation of osteoblast differentiation; GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway; GO:1904204 regulation of skeletal muscle hypertrophy; GO:0040013 negative regulation of locomotion; GO:0048729 tissue morphogenesis; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0022404 molting cycle process; GO:0007154 cell communication; GO:0044342 type B pancreatic cell proliferation; GO:0045596 negative regulation of cell differentiation; GO:0070887 cellular response to chemical stimulus; GO:0030324 lung development; GO:0032502 developmental process; GO:0035295 tube development; GO:0045926 negative regulation of growth; GO:0010468 regulation of gene expression; GO:0060429 epithelium development; GO:0009888 tissue development; GO:0031326 regulation of cellular biosynthetic process; GO:0010675 regulation of cellular carbohydrate metabolic process; GO:0048522 positive regulation of cellular process; GO:0090257 regulation of muscle system process; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0060056 mammary gland involution; GO:0071417 cellular response to organonitrogen compound; GO:0044723 single-organism carbohydrate metabolic process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0043434 response to peptide hormone; GO:1901699 cellular response to nitrogen compound; GO:0007568 aging; GO:0019222 regulation of metabolic process; GO:0048856 anatomical structure development; GO:0051271 negative regulation of cellular component movement; GO:0014733 regulation of skeletal muscle adaptation; GO:0040008 regulation of growth; GO:0048660 regulation of smooth muscle cell proliferation; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0048730 epidermis morphogenesis; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:0023056 positive regulation of signaling; GO:0005996 monosaccharide metabolic process; GO:0031069 hair follicle morphogenesis; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0048771 tissue remodeling; GO:0051146 striated muscle cell differentiation; GO:0051897 positive regulation of protein kinase B signaling; GO:0035556 intracellular signal transduction; GO:0010629 negative regulation of gene expression; GO:0071320 cellular response to cAMP; GO:1901861 regulation of muscle tissue development; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0060416 response to growth hormone; GO:0014741 negative regulation of muscle hypertrophy; GO:0048518 positive regulation of biological process; GO:0048662 negative regulation of smooth muscle cell proliferation; GO:1901701 cellular response to oxygen-containing compound; GO:0071495 cellular response to endogenous stimulus; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0006417 regulation of translation; GO:0044703 multi-organism reproductive process; GO:0042692 muscle cell differentiation; GO:0051248 negative regulation of protein metabolic process; GO:0030279 negative regulation of ossification; GO:0009967 positive regulation of signal transduction; GO:0031327 negative regulation of cellular biosynthetic process; GO:0051128 regulation of cellular component organization; GO:0040012 regulation of locomotion; GO:0009725 response to hormone; GO:0014910 regulation of smooth muscle cell migration; GO:0022612 gland morphogenesis; GO:0065007 biological regulation; ","GO:0042567 insulin-like growth factor ternary complex; GO:0044421 extracellular region part; GO:0005615 extracellular space; GO:0016942 insulin-like growth factor binding protein complex; GO:0005622 intracellular; GO:0044464 cell part; GO:0032991 macromolecular complex; GO:0043234 protein complex; GO:0005623 cell; GO:0005576 extracellular region; GO:0036454 growth factor complex; ","GO:0031994 insulin-like growth factor I binding; GO:0005520 insulin-like growth factor binding; GO:0005515 protein binding; GO:0001968 fibronectin binding; GO:0031995 insulin-like growth factor II binding; GO:0019838 growth factor binding; GO:0005488 binding; ",{"$nulls":3},"IPR000716; IPR000867; IPR009030; ","\"Thyroglobulin type-1; Insulin-like growth factor-binding protein, IGFBP; Growth factor receptor cysteine-rich domain; \"\r"]
["P24844","Myosin regulatory light polypeptide 9 OS=Homo sapiens OX=9606 GN=MYL9","MYL9",19.827,35.932,66.3,10,26,3,1.12,1.126,1.109,0.947,0.839,0.839,0.782,0.026,"mitochondria\r","GO:0044707 single-multicellular organism process; GO:0065008 regulation of biological quality; GO:0007596 blood coagulation; GO:0003012 muscle system process; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0034109 homotypic cell-cell adhesion; GO:0007599 hemostasis; GO:0051239 regulation of multicellular organismal process; GO:0009611 response to wounding; GO:0022610 biological adhesion; GO:0016337 single organismal cell-cell adhesion; GO:0006936 muscle contraction; GO:0007155 cell adhesion; GO:0044057 regulation of system process; GO:0009987 cellular process; GO:0003008 system process; GO:0050878 regulation of body fluid levels; GO:0006950 response to stress; GO:0030168 platelet activation; GO:0006937 regulation of muscle contraction; GO:0044763 single-organism cellular process; GO:0098609 cell-cell adhesion; GO:0090257 regulation of muscle system process; GO:0032501 multicellular organismal process; GO:0050789 regulation of biological process; GO:0042060 wound healing; GO:0098602 single organism cell adhesion; GO:0001775 cell activation; GO:0050817 coagulation; GO:0070527 platelet aggregation; GO:0065007 biological regulation; ","GO:0030016 myofibril; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0030018 Z disc; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0031674 I band; GO:0032432 actin filament bundle; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0044464 cell part; GO:0005622 intracellular; GO:0043292 contractile fiber; GO:0016460 myosin II complex; GO:0001725 stress fiber; GO:0016459 myosin complex; GO:0042641 actomyosin; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0005859 muscle myosin complex; GO:0097517 contractile actin filament bundle; GO:0005829 cytosol; GO:0015629 actin cytoskeleton; GO:0099081 supramolecular polymer; GO:0043226 organelle; GO:0030017 sarcomere; GO:0044449 contractile fiber part; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0008092 cytoskeletal protein binding; GO:0032036 myosin heavy chain binding; GO:0005488 binding; GO:0043167 ion binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0005509 calcium ion binding; GO:0017022 myosin binding; GO:0008307 structural constituent of muscle; GO:0005198 structural molecule activity; ","K12755","MYL9; myosin regulatory light chain 9","hsa04921 Oxytocin signaling pathway - Homo sapiens (human); hsa04024 cAMP signaling pathway - Homo sapiens (human); hsa04670 Leukocyte transendothelial migration - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa04530 Tight junction - Homo sapiens (human); hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa04270 Vascular smooth muscle contraction - Homo sapiens (human); ","IPR011992; IPR002048; ","EF-hand domain pair; EF-hand domain; \r"]
["P25189","Myelin protein P0 OS=Homo sapiens OX=9606 GN=MPZ","MPZ",27.554,18.487,21.8,6,12,6,1.052,1.076,0.987,0.916,0.912,0.962,0.896,0.024,"extracellular\r","GO:0044700 single organism signaling; GO:0050794 regulation of cellular process; GO:0010941 regulation of cell death; GO:0043069 negative regulation of programmed cell death; GO:0044763 single-organism cellular process; GO:0043067 regulation of programmed cell death; GO:0044699 single-organism process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0023052 signaling; GO:0050789 regulation of biological process; GO:0099536 synaptic signaling; GO:0007267 cell-cell signaling; GO:0007154 cell communication; GO:0043066 negative regulation of apoptotic process; GO:0099537 trans-synaptic signaling; GO:0098916 anterograde trans-synaptic signaling; GO:0007268 chemical synaptic transmission; GO:0009987 cellular process; GO:0060548 negative regulation of cell death; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016323 basolateral plasma membrane; GO:0016020 membrane; GO:0031226 intrinsic component of plasma membrane; GO:0005783 endoplasmic reticulum; GO:0005791 rough endoplasmic reticulum; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0098590 plasma membrane region; GO:0043209 myelin sheath; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0005764 lysosome; GO:0005773 vacuole; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0000323 lytic vacuole; ","GO:0005515 protein binding; GO:0005198 structural molecule activity; GO:0005488 binding; ","K06770","MPZ; myelin protein zero","hsa04514 Cell adhesion molecules (CAMs) - Homo sapiens (human); ","IPR019566; IPR007110; IPR013783; IPR003599; IPR013106; ","\"Myelin-PO, C-terminal; Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin subtype; Immunoglobulin V-set domain; \"\r"]
["P25311","Zinc-alpha-2-glycoprotein OS=Homo sapiens OX=9606 GN=AZGP1","AZGP1",34.258,109.41,47.7,15,32,15,1.023,1.022,0.961,1.003,1.008,0.98,0.995,0.846,"extracellular\r","GO:0050794 regulation of cellular process; GO:0009593 detection of chemical stimulus; GO:0044707 single-multicellular organism process; GO:0065008 regulation of biological quality; GO:0042127 regulation of cell proliferation; GO:0006725 cellular aromatic compound metabolic process; GO:0044699 single-organism process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0050913 sensory perception of bitter taste; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0050877 neurological system process; GO:0015031 protein transport; GO:0048871 multicellular organismal homeostasis; GO:0060249 anatomical structure homeostasis; GO:0008285 negative regulation of cell proliferation; GO:0071704 organic substance metabolic process; GO:0051234 establishment of localization; GO:0050909 sensory perception of taste; GO:0022610 biological adhesion; GO:0042592 homeostatic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0051606 detection of stimulus; GO:0007606 sensory perception of chemical stimulus; GO:0007155 cell adhesion; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0009987 cellular process; GO:0050906 detection of stimulus involved in sensory perception; GO:0007600 sensory perception; GO:0003008 system process; GO:0071806 protein transmembrane transport; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:0032501 multicellular organismal process; GO:0045184 establishment of protein localization; GO:0016070 RNA metabolic process; GO:0006810 transport; GO:0019882 antigen processing and presentation; GO:0055085 transmembrane transport; GO:0090501 RNA phosphodiester bond hydrolysis; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0090304 nucleic acid metabolic process; GO:0001895 retina homeostasis; GO:0050907 detection of chemical stimulus involved in sensory perception; GO:0001894 tissue homeostasis; GO:0044260 cellular macromolecule metabolic process; GO:0051179 localization; GO:0090305 nucleic acid phosphodiester bond hydrolysis; GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste; GO:0050912 detection of chemical stimulus involved in sensory perception of taste; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0043229 intracellular organelle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0008565 protein transporter activity; GO:0022884 macromolecule transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0008320 protein transmembrane transporter activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0003823 antigen binding; GO:0022891 substrate-specific transmembrane transporter activity; GO:0097367 carbohydrate derivative binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0004518 nuclease activity; GO:0001948 glycoprotein binding; GO:0004540 ribonuclease activity; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; ",{"$nulls":3},"IPR007110; IPR013783; IPR011161; IPR001039; IPR011162; IPR003597; ","\"Immunoglobulin-like domain; Immunoglobulin-like fold; MHC class I-like antigen recognition-like; MHC class I alpha chain, alpha1 alpha2 domains; MHC classes I/II-like antigen recognition protein; Immunoglobulin C1-set; \"\r"]
["P25325","3-mercaptopyruvate sulfurtransferase OS=Homo sapiens OX=9606 GN=MPST","MPST",33.178,26.794,33.7,9,12,9,1.069,1.073,1.109,0.939,0.914,0.979,0.871,0.00394,"mitochondria\r","GO:0044707 single-multicellular organism process; GO:0048732 gland development; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0072001 renal system development; GO:0070814 hydrogen sulfide biosynthetic process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0044272 sulfur compound biosynthetic process; GO:0000096 sulfur amino acid metabolic process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0009440 cyanate catabolic process; GO:0044248 cellular catabolic process; GO:0006534 cysteine metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0061008 hepaticobiliary system development; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0070813 hydrogen sulfide metabolic process; GO:0007399 nervous system development; GO:0006790 sulfur compound metabolic process; GO:0032502 developmental process; GO:0019346 transsulfuration; GO:0001822 kidney development; GO:0021510 spinal cord development; GO:0044712 single-organism catabolic process; GO:0048731 system development; GO:0009636 response to toxic substance; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:0009439 cyanate metabolic process; GO:0044238 primary metabolic process; GO:1901605 alpha-amino acid metabolic process; GO:0032501 multicellular organismal process; GO:0044249 cellular biosynthetic process; GO:0009092 homoserine metabolic process; GO:1901575 organic substance catabolic process; GO:0001889 liver development; GO:0001655 urogenital system development; GO:0048513 animal organ development; GO:1901565 organonitrogen compound catabolic process; GO:0042221 response to chemical; GO:0009069 serine family amino acid metabolic process; GO:0007417 central nervous system development; GO:0044710 single-organism metabolic process; GO:0044767 single-organism developmental process; GO:0019752 carboxylic acid metabolic process; GO:0050667 homocysteine metabolic process; GO:0006082 organic acid metabolic process; GO:0009056 catabolic process; GO:0048856 anatomical structure development; GO:0043436 oxoacid metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0044421 extracellular region part; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0045202 synapse; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016784 3-mercaptopyruvate sulfurtransferase activity; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0005515 protein binding; GO:0016782 transferase activity, transferring sulfur-containing groups; GO:0004792 thiosulfate sulfurtransferase activity; GO:0016783 sulfurtransferase activity; GO:0016740 transferase activity; ","K01011","TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]","hsa00920 Sulfur metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa04122 Sulfur relay system - Homo sapiens (human); hsa00270 Cysteine and methionine metabolism - Homo sapiens (human); ","IPR001763; ","Rhodanese-like domain; \r"]
["P25398","40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12","RPS12",14.515,57.539,53.8,7,24,7,0.899,0.883,0.876,1.099,1.087,1.136,1.25,1.25E-4,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0072594 establishment of protein localization to organelle; GO:0006518 peptide metabolic process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0051649 establishment of localization in cell; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0070972 protein localization to endoplasmic reticulum; GO:0006364 rRNA processing; GO:0006413 translational initiation; GO:1901361 organic cyclic compound catabolic process; GO:0033365 protein localization to organelle; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0006412 translation; GO:0016072 rRNA metabolic process; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0072657 protein localization to membrane; GO:0043043 peptide biosynthetic process; GO:0042254 ribosome biogenesis; GO:1901360 organic cyclic compound metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032774 RNA biosynthetic process; GO:0045047 protein targeting to ER; GO:0043603 cellular amide metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0006401 RNA catabolic process; GO:0016070 RNA metabolic process; GO:0019439 aromatic compound catabolic process; GO:1901575 organic substance catabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0019083 viral transcription; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0046907 intracellular transport; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0044267 cellular protein metabolic process; GO:0006613 cotranslational protein targeting to membrane; GO:0048519 negative regulation of biological process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0016032 viral process; GO:0019080 viral gene expression; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0006886 intracellular protein transport; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0034613 cellular protein localization; GO:0009059 macromolecule biosynthetic process; GO:0090150 establishment of protein localization to membrane; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0051179 localization; GO:0009056 catabolic process; GO:0034660 ncRNA metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0015935 small ribosomal subunit; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044391 ribosomal subunit; GO:0005622 intracellular; GO:0044464 cell part; GO:0044445 cytosolic part; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0022626 cytosolic ribosome; GO:0043229 intracellular organelle; GO:0005840 ribosome; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0022627 cytosolic small ribosomal subunit; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005198 structural molecule activity; GO:0003735 structural constituent of ribosome; ","K02951","RP-S12e; small subunit ribosomal protein S12e","hsa03010 Ribosome - Homo sapiens (human); ","IPR029064; IPR004038; ","50S ribosomal protein L30e-like; Ribosomal protein L7Ae/L30e/S12e/Gadd45; \r"]
["P25686","DnaJ homolog subfamily B member 2 OS=Homo sapiens OX=9606 GN=DNAJB2","DNAJB2",35.58,15.019,14.5,4,5,3,1.148,1.11,1.024,0.963,0.863,0.917,0.836,0.0181,"nucleus\r","GO:0032270 positive regulation of cellular protein metabolic process; GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0051129 negative regulation of cellular component organization; GO:0061077 chaperone-mediated protein folding; GO:0031331 positive regulation of cellular catabolic process; GO:0044699 single-organism process; GO:1903644 regulation of chaperone-mediated protein folding; GO:0036503 ERAD pathway; GO:0032091 negative regulation of protein binding; GO:0044237 cellular metabolic process; GO:0031400 negative regulation of protein modification process; GO:0031396 regulation of protein ubiquitination; GO:0006457 protein folding; GO:1903364 positive regulation of cellular protein catabolic process; GO:0008152 metabolic process; GO:0035966 response to topologically incorrect protein; GO:0030433 ubiquitin-dependent ERAD pathway; GO:0009893 positive regulation of metabolic process; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:1903362 regulation of cellular protein catabolic process; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0051098 regulation of binding; GO:0048522 positive regulation of cellular process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:1901575 organic substance catabolic process; GO:0090086 negative regulation of protein deubiquitination; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:0043462 regulation of ATPase activity; GO:0051100 negative regulation of binding; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0030163 protein catabolic process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0061136 regulation of proteasomal protein catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0065009 regulation of molecular function; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0090083 regulation of inclusion body assembly; GO:0032781 positive regulation of ATPase activity; GO:0044092 negative regulation of molecular function; GO:0042026 protein refolding; GO:0090084 negative regulation of inclusion body assembly; GO:1903332 regulation of protein folding; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0090085 regulation of protein deubiquitination; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0034976 response to endoplasmic reticulum stress; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:0060255 regulation of macromolecule metabolic process; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0044087 regulation of cellular component biogenesis; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0010498 proteasomal protein catabolic process; GO:0071704 organic substance metabolic process; GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0043393 regulation of protein binding; GO:1903322 positive regulation of protein modification by small protein conjugation or removal; GO:0045862 positive regulation of proteolysis; GO:0051345 positive regulation of hydrolase activity; GO:0009896 positive regulation of catabolic process; GO:0044248 cellular catabolic process; GO:0006508 proteolysis; GO:0032880 regulation of protein localization; GO:0042176 regulation of protein catabolic process; GO:0009987 cellular process; GO:0043632 modification-dependent macromolecule catabolic process; GO:0006986 response to unfolded protein; GO:0044265 cellular macromolecule catabolic process; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0045861 negative regulation of proteolysis; GO:0006950 response to stress; GO:0019941 modification-dependent protein catabolic process; GO:0044712 single-organism catabolic process; GO:1901800 positive regulation of proteasomal protein catabolic process; GO:0031401 positive regulation of protein modification process; GO:0030162 regulation of proteolysis; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0009892 negative regulation of metabolic process; GO:0043085 positive regulation of catalytic activity; GO:1903321 negative regulation of protein modification by small protein conjugation or removal; GO:0051247 positive regulation of protein metabolic process; GO:0031398 positive regulation of protein ubiquitination; GO:0051246 regulation of protein metabolic process; GO:0009057 macromolecule catabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0051128 regulation of cellular component organization; GO:0045732 positive regulation of protein catabolic process; GO:0009056 catabolic process; GO:0065007 biological regulation; GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0044446 intracellular organelle part; GO:0016234 inclusion body; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0044432 endoplasmic reticulum part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0031227 intrinsic component of endoplasmic reticulum membrane; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; ","GO:0031593 polyubiquitin binding; GO:0031072 heat shock protein binding; GO:0031625 ubiquitin protein ligase binding; GO:0051087 chaperone binding; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0044877 macromolecular complex binding; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0070628 proteasome binding; GO:0030544 Hsp70 protein binding; GO:0032182 ubiquitin-like protein binding; GO:0001671 ATPase activator activity; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0043130 ubiquitin binding; GO:0051082 unfolded protein binding; GO:0060590 ATPase regulator activity; GO:0044389 ubiquitin-like protein ligase binding; GO:0008047 enzyme activator activity; GO:0019899 enzyme binding; GO:0032403 protein complex binding; ","K09508","DNAJB2; DnaJ homolog subfamily B member 2","hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); ","IPR001623; ","DnaJ domain; \r"]
["P25786","Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1","PSMA1",29.555,75.142,43.7,15,30,15,0.967,0.962,0.961,1.016,1.043,1.01,1.062,3.98E-3,"cytoplasm\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0002220 innate immune response activating cell surface receptor signaling pathway; GO:0007166 cell surface receptor signaling pathway; GO:0010608 posttranscriptional regulation of gene expression; GO:0051443 positive regulation of ubiquitin-protein transferase activity; GO:0031347 regulation of defense response; GO:0071345 cellular response to cytokine stimulus; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:1903364 positive regulation of cellular protein catabolic process; GO:0008152 metabolic process; GO:0044093 positive regulation of molecular function; GO:0090263 positive regulation of canonical Wnt signaling pathway; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0051347 positive regulation of transferase activity; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0016055 Wnt signaling pathway; GO:1903362 regulation of cellular protein catabolic process; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0006521 regulation of cellular amino acid metabolic process; GO:0002758 innate immune response-activating signal transduction; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0010972 negative regulation of G2/M transition of mitotic cell cycle; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0060828 regulation of canonical Wnt signaling pathway; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0033209 tumor necrosis factor-mediated signaling pathway; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0000165 MAPK cascade; GO:1903506 regulation of nucleic acid-templated transcription; GO:2000058 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0019884 antigen processing and presentation of exogenous antigen; GO:1901575 organic substance catabolic process; GO:0010948 negative regulation of cell cycle process; GO:0007267 cell-cell signaling; GO:0002223 stimulatory C-type lectin receptor signaling pathway; GO:0032269 negative regulation of cellular protein metabolic process; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0030163 protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0060071 Wnt signaling pathway, planar cell polarity pathway; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:0002682 regulation of immune system process; GO:0006464 cellular protein modification process; GO:0031145 anaphase-promoting complex-dependent catabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016310 phosphorylation; GO:0033554 cellular response to stress; GO:0007346 regulation of mitotic cell cycle; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0051239 regulation of multicellular organismal process; GO:0043487 regulation of RNA stability; GO:0000209 protein polyubiquitination; GO:0031349 positive regulation of defense response; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0009889 regulation of biosynthetic process; GO:1901987 regulation of cell cycle phase transition; GO:0009896 positive regulation of catabolic process; GO:0043620 regulation of DNA-templated transcription in response to stress; GO:0070482 response to oxygen levels; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0044248 cellular catabolic process; GO:0010389 regulation of G2/M transition of mitotic cell cycle; GO:0042176 regulation of protein catabolic process; GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; GO:0038093 Fc receptor signaling pathway; GO:0050778 positive regulation of immune response; GO:0009966 regulation of signal transduction; GO:0023014 signal transduction by protein phosphorylation; GO:0071456 cellular response to hypoxia; GO:0038061 NIK/NF-kappaB signaling; GO:0002253 activation of immune response; GO:0006950 response to stress; GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; GO:0016567 protein ubiquitination; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress; GO:1904666 regulation of ubiquitin protein ligase activity; GO:1903321 negative regulation of protein modification by small protein conjugation or removal; GO:0055085 transmembrane transport; GO:0051247 positive regulation of protein metabolic process; GO:0051438 regulation of ubiquitin-protein transferase activity; GO:0031398 positive regulation of protein ubiquitination; GO:0032446 protein modification by small protein conjugation; GO:0006793 phosphorus metabolic process; GO:0030111 regulation of Wnt signaling pathway; GO:0031325 positive regulation of cellular metabolic process; GO:0030177 positive regulation of Wnt signaling pathway; GO:1904668 positive regulation of ubiquitin protein ligase activity; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0036293 response to decreased oxygen levels; GO:0051179 localization; GO:0043412 macromolecule modification; GO:0048584 positive regulation of response to stimulus; GO:0050793 regulation of developmental process; GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process; GO:0051444 negative regulation of ubiquitin-protein transferase activity; GO:0070646 protein modification by small protein removal; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0031331 positive regulation of cellular catabolic process; GO:0090090 negative regulation of canonical Wnt signaling pathway; GO:0044699 single-organism process; GO:0031400 negative regulation of protein modification process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0035567 non-canonical Wnt signaling pathway; GO:0031396 regulation of protein ubiquitination; GO:1905330 regulation of morphogenesis of an epithelium; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0045930 negative regulation of mitotic cell cycle; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0045088 regulation of innate immune response; GO:1901991 negative regulation of mitotic cell cycle phase transition; GO:0009893 positive regulation of metabolic process; GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0034612 response to tumor necrosis factor; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0051726 regulation of cell cycle; GO:0070887 cellular response to chemical stimulus; GO:0050851 antigen receptor-mediated signaling pathway; GO:0010468 regulation of gene expression; GO:0030178 negative regulation of Wnt signaling pathway; GO:0034097 response to cytokine; GO:0031326 regulation of cellular biosynthetic process; GO:0048002 antigen processing and presentation of peptide antigen; GO:0048522 positive regulation of cellular process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0051348 negative regulation of transferase activity; GO:0070647 protein modification by small protein conjugation or removal; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0198738 cell-cell signaling by wnt; GO:0010565 regulation of cellular ketone metabolic process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0036211 protein modification process; GO:2000026 regulation of multicellular organismal development; GO:0090175 regulation of establishment of planar polarity; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0045786 negative regulation of cell cycle; GO:1904667 negative regulation of ubiquitin protein ligase activity; GO:0002218 activation of innate immune response; GO:0044257 cellular protein catabolic process; GO:0071356 cellular response to tumor necrosis factor; GO:1901988 negative regulation of cell cycle phase transition; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0016579 protein deubiquitination; GO:0050896 response to stimulus; GO:0010498 proteasomal protein catabolic process; GO:0071704 organic substance metabolic process; GO:1903322 positive regulation of protein modification by small protein conjugation or removal; GO:0045862 positive regulation of proteolysis; GO:2000027 regulation of organ morphogenesis; GO:0006468 protein phosphorylation; GO:0023056 positive regulation of signaling; GO:0001666 response to hypoxia; GO:0002757 immune response-activating signal transduction; GO:0006508 proteolysis; GO:0010647 positive regulation of cell communication; GO:0071453 cellular response to oxygen levels; GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:0019221 cytokine-mediated signaling pathway; GO:0009987 cellular process; GO:0033238 regulation of cellular amine metabolic process; GO:0031397 negative regulation of protein ubiquitination; GO:0043632 modification-dependent macromolecule catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0045089 positive regulation of innate immune response; GO:0006355 regulation of transcription, DNA-templated; GO:0035556 intracellular signal transduction; GO:0019941 modification-dependent protein catabolic process; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition; GO:0031401 positive regulation of protein modification process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia; GO:1902749 regulation of cell cycle G2/M phase transition; GO:0043488 regulation of mRNA stability; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0019882 antigen processing and presentation; GO:0050852 T cell receptor signaling pathway; GO:0051246 regulation of protein metabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0002684 positive regulation of immune system process; GO:0009057 macromolecule catabolic process; GO:0038095 Fc-epsilon receptor signaling pathway; GO:0051248 negative regulation of protein metabolic process; GO:0022402 cell cycle process; GO:0045732 positive regulation of protein catabolic process; GO:0009967 positive regulation of signal transduction; GO:1902750 negative regulation of cell cycle G2/M phase transition; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0036294 cellular response to decreased oxygen levels; GO:0065007 biological regulation; ","GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:1905369 endopeptidase complex; GO:0005856 cytoskeleton; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0005815 microtubule organizing center; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:1905368 peptidase complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0019773 proteasome core complex, alpha-subunit complex; GO:0000502 proteasome complex; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005813 centrosome; GO:0005839 proteasome core complex; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0005844 polysome; GO:0044428 nuclear part; ","GO:0004175 endopeptidase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0004298 threonine-type endopeptidase activity; GO:0008233 peptidase activity; GO:0070003 threonine-type peptidase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0016787 hydrolase activity; GO:0005515 protein binding; ","K02725","PSMA1; 20S proteasome subunit alpha 6 [EC:3.4.25.1]","hsa03050 Proteasome - Homo sapiens (human); ","IPR000426; IPR029055; ","\"Proteasome alpha-subunit, N-terminal domain; Nucleophile aminohydrolases, N-terminal; \"\r"]
["P25788","Proteasome subunit alpha type-3 OS=Homo sapiens OX=9606 GN=PSMA3","PSMA3",28.433,33.111,41.2,11,19,11,0.958,1.019,0.986,1.024,1.046,1.03,1.046,0.0741,"cytoplasm\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0002220 innate immune response activating cell surface receptor signaling pathway; GO:0007166 cell surface receptor signaling pathway; GO:0010608 posttranscriptional regulation of gene expression; GO:0051443 positive regulation of ubiquitin-protein transferase activity; GO:0031347 regulation of defense response; GO:0071345 cellular response to cytokine stimulus; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:1903364 positive regulation of cellular protein catabolic process; GO:0008152 metabolic process; GO:0044093 positive regulation of molecular function; GO:0090263 positive regulation of canonical Wnt signaling pathway; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0051347 positive regulation of transferase activity; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0016055 Wnt signaling pathway; GO:0044419 interspecies interaction between organisms; GO:1903362 regulation of cellular protein catabolic process; GO:0052548 regulation of endopeptidase activity; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0006521 regulation of cellular amino acid metabolic process; GO:0002758 innate immune response-activating signal transduction; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0010972 negative regulation of G2/M transition of mitotic cell cycle; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0060828 regulation of canonical Wnt signaling pathway; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0033209 tumor necrosis factor-mediated signaling pathway; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0000165 MAPK cascade; GO:1903506 regulation of nucleic acid-templated transcription; GO:2000058 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0019884 antigen processing and presentation of exogenous antigen; GO:1901575 organic substance catabolic process; GO:0010948 negative regulation of cell cycle process; GO:0007267 cell-cell signaling; GO:0002223 stimulatory C-type lectin receptor signaling pathway; GO:0051336 regulation of hydrolase activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0030163 protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0060071 Wnt signaling pathway, planar cell polarity pathway; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:0002682 regulation of immune system process; GO:0006464 cellular protein modification process; GO:0031145 anaphase-promoting complex-dependent catabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016310 phosphorylation; GO:0033554 cellular response to stress; GO:0007346 regulation of mitotic cell cycle; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0051239 regulation of multicellular organismal process; GO:0043487 regulation of RNA stability; GO:0000209 protein polyubiquitination; GO:0031349 positive regulation of defense response; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0009889 regulation of biosynthetic process; GO:1901987 regulation of cell cycle phase transition; GO:0009896 positive regulation of catabolic process; GO:0043620 regulation of DNA-templated transcription in response to stress; GO:0070482 response to oxygen levels; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0044248 cellular catabolic process; GO:0010389 regulation of G2/M transition of mitotic cell cycle; GO:0042176 regulation of protein catabolic process; GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; GO:0038093 Fc receptor signaling pathway; GO:0050778 positive regulation of immune response; GO:0009966 regulation of signal transduction; GO:0023014 signal transduction by protein phosphorylation; GO:0071456 cellular response to hypoxia; GO:0038061 NIK/NF-kappaB signaling; GO:0002253 activation of immune response; GO:0006950 response to stress; GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; GO:0016567 protein ubiquitination; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress; GO:1904666 regulation of ubiquitin protein ligase activity; GO:1903321 negative regulation of protein modification by small protein conjugation or removal; GO:0055085 transmembrane transport; GO:0051247 positive regulation of protein metabolic process; GO:0051438 regulation of ubiquitin-protein transferase activity; GO:0031398 positive regulation of protein ubiquitination; GO:0032446 protein modification by small protein conjugation; GO:0006793 phosphorus metabolic process; GO:0030111 regulation of Wnt signaling pathway; GO:0031325 positive regulation of cellular metabolic process; GO:0030177 positive regulation of Wnt signaling pathway; GO:1904668 positive regulation of ubiquitin protein ligase activity; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0036293 response to decreased oxygen levels; GO:0051179 localization; GO:0043412 macromolecule modification; GO:0048584 positive regulation of response to stimulus; GO:0050793 regulation of developmental process; GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process; GO:0051444 negative regulation of ubiquitin-protein transferase activity; GO:0070646 protein modification by small protein removal; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0031331 positive regulation of cellular catabolic process; GO:0090090 negative regulation of canonical Wnt signaling pathway; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0031400 negative regulation of protein modification process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0035567 non-canonical Wnt signaling pathway; GO:0031396 regulation of protein ubiquitination; GO:1905330 regulation of morphogenesis of an epithelium; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0045930 negative regulation of mitotic cell cycle; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0045088 regulation of innate immune response; GO:1901991 negative regulation of mitotic cell cycle phase transition; GO:0009893 positive regulation of metabolic process; GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0034612 response to tumor necrosis factor; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0051726 regulation of cell cycle; GO:0070887 cellular response to chemical stimulus; GO:0050851 antigen receptor-mediated signaling pathway; GO:0010468 regulation of gene expression; GO:0030178 negative regulation of Wnt signaling pathway; GO:0034097 response to cytokine; GO:0031326 regulation of cellular biosynthetic process; GO:0048002 antigen processing and presentation of peptide antigen; GO:0048522 positive regulation of cellular process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0051348 negative regulation of transferase activity; GO:0070647 protein modification by small protein conjugation or removal; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0198738 cell-cell signaling by wnt; GO:0010565 regulation of cellular ketone metabolic process; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0036211 protein modification process; GO:0052547 regulation of peptidase activity; GO:2000026 regulation of multicellular organismal development; GO:0090175 regulation of establishment of planar polarity; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0045786 negative regulation of cell cycle; GO:1904667 negative regulation of ubiquitin protein ligase activity; GO:0002218 activation of innate immune response; GO:0044257 cellular protein catabolic process; GO:0071356 cellular response to tumor necrosis factor; GO:1901988 negative regulation of cell cycle phase transition; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0016579 protein deubiquitination; GO:0050896 response to stimulus; GO:0010498 proteasomal protein catabolic process; GO:0071704 organic substance metabolic process; GO:1903322 positive regulation of protein modification by small protein conjugation or removal; GO:0045862 positive regulation of proteolysis; GO:2000027 regulation of organ morphogenesis; GO:0006468 protein phosphorylation; GO:0023056 positive regulation of signaling; GO:0016032 viral process; GO:0001666 response to hypoxia; GO:0002757 immune response-activating signal transduction; GO:0006508 proteolysis; GO:0010647 positive regulation of cell communication; GO:0071453 cellular response to oxygen levels; GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:0019221 cytokine-mediated signaling pathway; GO:0009987 cellular process; GO:0033238 regulation of cellular amine metabolic process; GO:0031397 negative regulation of protein ubiquitination; GO:0043632 modification-dependent macromolecule catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0045089 positive regulation of innate immune response; GO:0006355 regulation of transcription, DNA-templated; GO:0035556 intracellular signal transduction; GO:0019941 modification-dependent protein catabolic process; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0031401 positive regulation of protein modification process; GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia; GO:1902749 regulation of cell cycle G2/M phase transition; GO:0043488 regulation of mRNA stability; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0019882 antigen processing and presentation; GO:0050852 T cell receptor signaling pathway; GO:0051246 regulation of protein metabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0002684 positive regulation of immune system process; GO:0009057 macromolecule catabolic process; GO:0038095 Fc-epsilon receptor signaling pathway; GO:0051248 negative regulation of protein metabolic process; GO:0022402 cell cycle process; GO:0045732 positive regulation of protein catabolic process; GO:0009967 positive regulation of signal transduction; GO:1902750 negative regulation of cell cycle G2/M phase transition; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0036294 cellular response to decreased oxygen levels; GO:0065007 biological regulation; ","GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:1905369 endopeptidase complex; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:1905368 peptidase complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0019773 proteasome core complex, alpha-subunit complex; GO:0000502 proteasome complex; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0045202 synapse; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005839 proteasome core complex; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0004175 endopeptidase activity; GO:0004298 threonine-type endopeptidase activity; GO:0008233 peptidase activity; GO:0070003 threonine-type peptidase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0016787 hydrolase activity; GO:0005515 protein binding; ","K02727","PSMA3; 20S proteasome subunit alpha 7 [EC:3.4.25.1]","hsa03050 Proteasome - Homo sapiens (human); ","IPR000426; IPR029055; ","\"Proteasome alpha-subunit, N-terminal domain; Nucleophile aminohydrolases, N-terminal; \"\r"]
["P25942","Tumor necrosis factor receptor superfamily member 5 OS=Homo sapiens OX=9606 GN=CD40","CD40",30.619,2.295,3.6,1,1,1,0.965,0.883,0.879,0.984,1.176,1.106,1.198,0.0418,"extracellular\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0002694 regulation of leukocyte activation; GO:0010941 regulation of cell death; GO:0045191 regulation of isotype switching; GO:0098542 defense response to other organism; GO:0009891 positive regulation of biosynthetic process; GO:0070555 response to interleukin-1; GO:0009607 response to biotic stimulus; GO:0030888 regulation of B cell proliferation; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0032946 positive regulation of mononuclear cell proliferation; GO:0065003 macromolecular complex assembly; GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling; GO:0044093 positive regulation of molecular function; GO:0055065 metal ion homeostasis; GO:0000018 regulation of DNA recombination; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0090036 regulation of protein kinase C signaling; GO:0071214 cellular response to abiotic stimulus; GO:0030168 platelet activation; GO:0051054 positive regulation of DNA metabolic process; GO:0080090 regulation of primary metabolic process; GO:0050864 regulation of B cell activation; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:2000353 positive regulation of endothelial cell apoptotic process; GO:0033209 tumor necrosis factor-mediated signaling pathway; GO:0006874 cellular calcium ion homeostasis; GO:0071396 cellular response to lipid; GO:0051704 multi-organism process; GO:0036017 response to erythropoietin; GO:0050776 regulation of immune response; GO:0010243 response to organonitrogen compound; GO:0002889 regulation of immunoglobulin mediated immune response; GO:0051092 positive regulation of NF-kappaB transcription factor activity; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0051223 regulation of protein transport; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0044707 single-multicellular organism process; GO:0097190 apoptotic signaling pathway; GO:0001819 positive regulation of cytokine production; GO:1901700 response to oxygen-containing compound; GO:0050867 positive regulation of cell activation; GO:0051345 positive regulation of hydrolase activity; GO:0009889 regulation of biosynthetic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0042100 B cell proliferation; GO:0050778 positive regulation of immune response; GO:0048878 chemical homeostasis; GO:0006950 response to stress; GO:0032496 response to lipopolysaccharide; GO:0002376 immune system process; GO:0008283 cell proliferation; GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein; GO:0010033 response to organic substance; GO:0007584 response to nutrient; GO:0048302 regulation of isotype switching to IgG isotypes; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0002696 positive regulation of leukocyte activation; GO:0031325 positive regulation of cellular metabolic process; GO:0071219 cellular response to molecule of bacterial origin; GO:0006955 immune response; GO:0008284 positive regulation of cell proliferation; GO:0023051 regulation of signaling; GO:0051046 regulation of secretion; GO:0044699 single-organism process; GO:0009611 response to wounding; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0006915 apoptotic process; GO:0002819 regulation of adaptive immune response; GO:0070663 regulation of leukocyte proliferation; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0048304 positive regulation of isotype switching to IgG isotypes; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0034612 response to tumor necrosis factor; GO:0033674 positive regulation of kinase activity; GO:0033273 response to vitamin; GO:0002708 positive regulation of lymphocyte mediated immunity; GO:0001562 response to protozoan; GO:0032943 mononuclear cell proliferation; GO:0045937 positive regulation of phosphate metabolic process; GO:0031326 regulation of cellular biosynthetic process; GO:0034097 response to cytokine; GO:0002237 response to molecule of bacterial origin; GO:0098771 inorganic ion homeostasis; GO:0002700 regulation of production of molecular mediator of immune response; GO:1903530 regulation of secretion by cell; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0010942 positive regulation of cell death; GO:0033590 response to cobalamin; GO:0051607 defense response to virus; GO:0051052 regulation of DNA metabolic process; GO:0002705 positive regulation of leukocyte mediated immunity; GO:0006954 inflammatory response; GO:0070661 leukocyte proliferation; GO:0043087 regulation of GTPase activity; GO:0065009 regulation of molecular function; GO:0006952 defense response; GO:0070271 protein complex biogenesis; GO:0009615 response to virus; GO:0043549 regulation of kinase activity; GO:0002891 positive regulation of immunoglobulin mediated immune response; GO:0046425 regulation of JAK-STAT cascade; GO:0016043 cellular component organization; GO:0071260 cellular response to mechanical stimulus; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0043065 positive regulation of apoptotic process; GO:0046651 lymphocyte proliferation; GO:0051707 response to other organism; GO:0045087 innate immune response; GO:0042592 homeostatic process; GO:0033993 response to lipid; GO:0009612 response to mechanical stimulus; GO:0043408 regulation of MAPK cascade; GO:0055080 cation homeostasis; GO:0016032 viral process; GO:0023056 positive regulation of signaling; GO:0010647 positive regulation of cell communication; GO:0019221 cytokine-mediated signaling pathway; GO:0050878 regulation of body fluid levels; GO:0006355 regulation of transcription, DNA-templated; GO:0035556 intracellular signal transduction; GO:0051049 regulation of transport; GO:0002699 positive regulation of immune effector process; GO:0001932 regulation of protein phosphorylation; GO:0034341 response to interferon-gamma; GO:0001934 positive regulation of protein phosphorylation; GO:0043085 positive regulation of catalytic activity; GO:0043933 macromolecular complex subunit organization; GO:0002703 regulation of leukocyte mediated immunity; GO:1901701 cellular response to oxygen-containing compound; GO:0008219 cell death; GO:0045830 positive regulation of isotype switching; GO:0002684 positive regulation of immune system process; GO:0001817 regulation of cytokine production; GO:0045911 positive regulation of DNA recombination; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0032944 regulation of mononuclear cell proliferation; GO:0032270 positive regulation of cellular protein metabolic process; GO:0045321 leukocyte activation; GO:2000351 regulation of endothelial cell apoptotic process; GO:0007166 cell surface receptor signaling pathway; GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0071345 cellular response to cytokine stimulus; GO:0009605 response to external stimulus; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0009719 response to endogenous stimulus; GO:0010562 positive regulation of phosphorus metabolic process; GO:0042327 positive regulation of phosphorylation; GO:0051347 positive regulation of transferase activity; GO:0044419 interspecies interaction between organisms; GO:1901652 response to peptide; GO:0014070 response to organic cyclic compound; GO:0051174 regulation of phosphorus metabolic process; GO:0002639 positive regulation of immunoglobulin production; GO:0045893 positive regulation of transcription, DNA-templated; GO:0046427 positive regulation of JAK-STAT cascade; GO:0050670 regulation of lymphocyte proliferation; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0042510 regulation of tyrosine phosphorylation of Stat1 protein; GO:1903506 regulation of nucleic acid-templated transcription; GO:0051336 regulation of hydrolase activity; GO:0051090 regulation of sequence-specific DNA binding transcription factor activity; GO:0050790 regulation of catalytic activity; GO:0010604 positive regulation of macromolecule metabolic process; GO:0002682 regulation of immune system process; GO:0050817 coagulation; GO:0051023 regulation of immunoglobulin secretion; GO:0002821 positive regulation of adaptive immune response; GO:0051094 positive regulation of developmental process; GO:0043068 positive regulation of programmed cell death; GO:0050794 regulation of cellular process; GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation; GO:0042127 regulation of cell proliferation; GO:0009628 response to abiotic stimulus; GO:0042509 regulation of tyrosine phosphorylation of STAT protein; GO:0031399 regulation of protein modification process; GO:0030890 positive regulation of B cell proliferation; GO:0043067 regulation of programmed cell death; GO:0071902 positive regulation of protein serine/threonine kinase activity; GO:0042511 positive regulation of tyrosine phosphorylation of Stat1 protein; GO:0051239 regulation of multicellular organismal process; GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0010628 positive regulation of gene expression; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0032880 regulation of protein localization; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:0009617 response to bacterium; GO:0006461 protein complex assembly; GO:1904892 regulation of STAT cascade; GO:1904035 regulation of epithelial cell apoptotic process; GO:0051254 positive regulation of RNA metabolic process; GO:1902531 regulation of intracellular signal transduction; GO:0043547 positive regulation of GTPase activity; GO:0071496 cellular response to external stimulus; GO:0043406 positive regulation of MAP kinase activity; GO:0051247 positive regulation of protein metabolic process; GO:0006873 cellular ion homeostasis; GO:0001775 cell activation; GO:0012501 programmed cell death; GO:0048584 positive regulation of response to stimulus; GO:0031328 positive regulation of cellular biosynthetic process; GO:0050793 regulation of developmental process; GO:0002702 positive regulation of production of molecular mediator of immune response; GO:0072503 cellular divalent inorganic cation homeostasis; GO:0043491 protein kinase B signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0044764 multi-organism cellular process; GO:0051249 regulation of lymphocyte activation; GO:1904894 positive regulation of STAT cascade; GO:0010646 regulation of cell communication; GO:0050671 positive regulation of lymphocyte proliferation; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0002697 regulation of immune effector process; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0071822 protein complex subunit organization; GO:0050801 ion homeostasis; GO:0055074 calcium ion homeostasis; GO:0036018 cellular response to erythropoietin; GO:0048522 positive regulation of cellular process; GO:0019725 cellular homeostasis; GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity; GO:0051251 positive regulation of lymphocyte activation; GO:0090037 positive regulation of protein kinase C signaling; GO:0042832 defense response to protozoan; GO:0032268 regulation of cellular protein metabolic process; GO:0050865 regulation of cell activation; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0048856 anatomical structure development; GO:0072507 divalent inorganic cation homeostasis; GO:2000026 regulation of multicellular organismal development; GO:0045859 regulation of protein kinase activity; GO:0071222 cellular response to lipopolysaccharide; GO:0002252 immune effector process; GO:0050730 regulation of peptidyl-tyrosine phosphorylation; GO:0071356 cellular response to tumor necrosis factor; GO:0043405 regulation of MAP kinase activity; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0030003 cellular cation homeostasis; GO:0071347 cellular response to interleukin-1; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0002706 regulation of lymphocyte mediated immunity; GO:0070201 regulation of establishment of protein localization; GO:0007599 hemostasis; GO:0055082 cellular chemical homeostasis; GO:0009991 response to extracellular stimulus; GO:0071216 cellular response to biotic stimulus; GO:0050871 positive regulation of B cell activation; GO:0050708 regulation of protein secretion; GO:0002714 positive regulation of B cell mediated immunity; GO:0009987 cellular process; GO:0042113 B cell activation; GO:0002712 regulation of B cell mediated immunity; GO:0031401 positive regulation of protein modification process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0046649 lymphocyte activation; GO:0010556 regulation of macromolecule biosynthetic process; GO:0032735 positive regulation of interleukin-12 production; GO:1904037 positive regulation of epithelial cell apoptotic process; GO:0045860 positive regulation of protein kinase activity; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0070665 positive regulation of leukocyte proliferation; GO:0042060 wound healing; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0002637 regulation of immunoglobulin production; GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0006875 cellular metal ion homeostasis; GO:0031667 response to nutrient levels; GO:0009967 positive regulation of signal transduction; GO:0043410 positive regulation of MAPK cascade; GO:0032655 regulation of interleukin-12 production; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0009897 external side of plasma membrane; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0043025 neuronal cell body; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0043196 varicosity; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0070062 extracellular exosome; GO:0044304 main axon; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0035631 CD40 receptor complex; GO:0098552 side of membrane; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0031226 intrinsic component of plasma membrane; GO:0098802 plasma membrane receptor complex; GO:0043235 receptor complex; GO:0044463 cell projection part; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0033267 axon part; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0030424 axon; GO:0036477 somatodendritic compartment; GO:0044459 plasma membrane part; GO:0009986 cell surface; GO:0044297 cell body; GO:0043230 extracellular organelle; ","GO:0038023 signaling receptor activity; GO:0031625 ubiquitin protein ligase binding; GO:0005035 death receptor activity; GO:0005515 protein binding; GO:0004888 transmembrane signaling receptor activity; GO:0004871 signal transducer activity; GO:0003823 antigen binding; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0005488 binding; GO:0005031 tumor necrosis factor-activated receptor activity; GO:0019904 protein domain specific binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0019899 enzyme binding; GO:0099600 transmembrane receptor activity; ","K03160","TNFRSF5; tumor necrosis factor receptor superfamily member 5","hsa05330 Allograft rejection - Homo sapiens (human); hsa05144 Malaria - Homo sapiens (human); hsa05322 Systemic lupus erythematosus - Homo sapiens (human); hsa04672 Intestinal immune network for IgA production - Homo sapiens (human); hsa04620 Toll-like receptor signaling pathway - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); hsa05310 Asthma - Homo sapiens (human); hsa05416 Viral myocarditis - Homo sapiens (human); hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human); hsa05166 HTLV-I infection - Homo sapiens (human); hsa05340 Primary immunodeficiency - Homo sapiens (human); hsa04514 Cell adhesion molecules (CAMs) - Homo sapiens (human); hsa05320 Autoimmune thyroid disease - Homo sapiens (human); hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human); hsa05145 Toxoplasmosis - Homo sapiens (human); hsa04064 NF-kappa B signaling pathway - Homo sapiens (human); ","IPR001368; IPR034021; ","\"TNFR/NGFR cysteine-rich region; Tumour necrosis factor receptor 5, N-terminal; \"\r"]
["P26038","Moesin OS=Homo sapiens OX=9606 GN=MSN","MSN",67.819,211.21,55.8,39,94,27,0.974,0.989,0.97,0.998,1.05,1.021,1.046,0.0463,"cytoplasm\r","GO:0001738 morphogenesis of a polarized epithelium; GO:0060627 regulation of vesicle-mediated transport; GO:0065008 regulation of biological quality; GO:0048732 gland development; GO:0032270 positive regulation of cellular protein metabolic process; GO:0035088 establishment or maintenance of apical/basal cell polarity; GO:1903364 positive regulation of cellular protein catabolic process; GO:0022610 biological adhesion; GO:0071801 regulation of podosome assembly; GO:1903651 positive regulation of cytoplasmic transport; GO:0032879 regulation of localization; GO:0008360 regulation of cell shape; GO:0032535 regulation of cellular component size; GO:0007155 cell adhesion; GO:1903362 regulation of cellular protein catabolic process; GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0002064 epithelial cell development; GO:1902966 positive regulation of protein localization to early endosome; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:1905668 positive regulation of protein localization to endosome; GO:0048870 cell motility; GO:0007163 establishment or maintenance of cell polarity; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0071396 cellular response to lipid; GO:0048513 animal organ development; GO:0045198 establishment of epithelial cell apical/basal polarity; GO:1905666 regulation of protein localization to endosome; GO:0050900 leukocyte migration; GO:0098602 single organism cell adhesion; GO:0009887 animal organ morphogenesis; GO:0010604 positive regulation of macromolecule metabolic process; GO:0002682 regulation of immune system process; GO:0002685 regulation of leukocyte migration; GO:0030855 epithelial cell differentiation; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0002009 morphogenesis of an epithelium; GO:0030859 polarized epithelial cell differentiation; GO:1901700 response to oxygen-containing compound; GO:0060341 regulation of cellular localization; GO:0009653 anatomical structure morphogenesis; GO:2000145 regulation of cell motility; GO:0010628 positive regulation of gene expression; GO:0009896 positive regulation of catabolic process; GO:2000641 regulation of early endosome to late endosome transport; GO:0007275 multicellular organism development; GO:0032880 regulation of protein localization; GO:0042176 regulation of protein catabolic process; GO:0061245 establishment or maintenance of bipolar cell polarity; GO:0035089 establishment of apical/basal cell polarity; GO:0007010 cytoskeleton organization; GO:1901655 cellular response to ketone; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0030334 regulation of cell migration; GO:0002376 immune system process; GO:0071407 cellular response to organic cyclic compound; GO:0010033 response to organic substance; GO:0003158 endothelium development; GO:0051247 positive regulation of protein metabolic process; GO:0006996 organelle organization; GO:0001885 endothelial cell development; GO:0031325 positive regulation of cellular metabolic process; GO:0006928 movement of cell or subcellular component; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:1903827 regulation of cellular protein localization; GO:0051674 localization of cell; GO:0061162 establishment of monopolar cell polarity; GO:0031331 positive regulation of cellular catabolic process; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0045446 endothelial cell differentiation; GO:1902115 regulation of organelle assembly; GO:0051130 positive regulation of cellular component organization; GO:0016337 single organismal cell-cell adhesion; GO:0048729 tissue morphogenesis; GO:0009893 positive regulation of metabolic process; GO:0031334 positive regulation of protein complex assembly; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:2000643 positive regulation of early endosome to late endosome transport; GO:0010468 regulation of gene expression; GO:0060429 epithelium development; GO:0071803 positive regulation of podosome assembly; GO:0009888 tissue development; GO:0090162 establishment of epithelial cell polarity; GO:1903649 regulation of cytoplasmic transport; GO:0098609 cell-cell adhesion; GO:0048522 positive regulation of cellular process; GO:0032386 regulation of intracellular transport; GO:0033574 response to testosterone; GO:1902965 regulation of protein localization to early endosome; GO:0051050 positive regulation of transport; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0043254 regulation of protein complex assembly; GO:0042221 response to chemical; GO:0010638 positive regulation of organelle organization; GO:1902117 positive regulation of organelle assembly; GO:0019222 regulation of metabolic process; GO:0040011 locomotion; GO:0061339 establishment or maintenance of monopolar cell polarity; GO:0048856 anatomical structure development; GO:0016043 cellular component organization; GO:0016477 cell migration; GO:0007159 leukocyte cell-cell adhesion; GO:0060255 regulation of macromolecule metabolic process; GO:1903829 positive regulation of cellular protein localization; GO:0071310 cellular response to organic substance; GO:0044087 regulation of cellular component biogenesis; GO:0050896 response to stimulus; GO:0022406 membrane docking; GO:0048468 cell development; GO:0033993 response to lipid; GO:0030154 cell differentiation; GO:0008361 regulation of cell size; GO:0030010 establishment of cell polarity; GO:0009987 cellular process; GO:0061028 establishment of endothelial barrier; GO:0032388 positive regulation of intracellular transport; GO:0051049 regulation of transport; GO:0033043 regulation of organelle organization; GO:0048518 positive regulation of biological process; GO:0071394 cellular response to testosterone stimulus; GO:1901701 cellular response to oxygen-containing compound; GO:2000401 regulation of lymphocyte migration; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0090066 regulation of anatomical structure size; GO:0022614 membrane to membrane docking; GO:0045732 positive regulation of protein catabolic process; GO:0051128 regulation of cellular component organization; GO:0040012 regulation of locomotion; GO:0022604 regulation of cell morphogenesis; GO:0044089 positive regulation of cellular component biogenesis; GO:0022612 gland morphogenesis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:1901654 response to ketone; ","GO:0016323 basolateral plasma membrane; GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0016324 apical plasma membrane; GO:0019898 extrinsic component of membrane; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0098858 actin-based cell projection; GO:0005623 cell; GO:0031143 pseudopodium; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0098590 plasma membrane region; GO:0043209 myelin sheath; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030175 filopodium; GO:0048471 perinuclear region of cytoplasm; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0031528 microvillus membrane; GO:0045177 apical part of cell; GO:0005924 cell-substrate adherens junction; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0001931 uropod; GO:0070161 anchoring junction; GO:0031254 cell trailing edge; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0072562 blood microparticle; GO:0044459 plasma membrane part; GO:0005902 microvillus; GO:0031253 cell projection membrane; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0003723 RNA binding; GO:0005102 receptor binding; GO:0003725 double-stranded RNA binding; GO:0019901 protein kinase binding; GO:0005515 protein binding; GO:0019900 kinase binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0050839 cell adhesion molecule binding; GO:0008092 cytoskeletal protein binding; GO:0005200 structural constituent of cytoskeleton; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0003779 actin binding; GO:0005198 structural molecule activity; GO:0019899 enzyme binding; ","K05763","MSN; moesin","hsa05162 Measles - Homo sapiens (human); hsa04670 Leukocyte transendothelial migration - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa04530 Tight junction - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); ","IPR019748; IPR018980; IPR008954; IPR019749; IPR018979; IPR011993; IPR029071; IPR011259; IPR014352; IPR000299; ","\"FERM central domain; FERM, C-terminal PH-like domain; Moesin tail domain; Band 4.1 domain; FERM, N-terminal; PH domain-like; Ubiquitin-related domain; Ezrin/radixin/moesin, C-terminal; FERM/acyl-CoA-binding protein, 3-helical bundle; FERM domain; \"\r"]
["P26368","Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2","U2AF2",53.5,34.823,25.1,8,11,8,1.004,0.979,0.911,1.038,1.013,1.045,1.07,0.0898,"nucleus\r","GO:0050658 RNA transport; GO:1903955 positive regulation of protein targeting to mitochondrion; GO:0097659 nucleic acid-templated transcription; GO:1903533 regulation of protein targeting; GO:0050686 negative regulation of mRNA processing; GO:0051169 nuclear transport; GO:0044237 cellular metabolic process; GO:0010821 regulation of mitochondrion organization; GO:0015031 protein transport; GO:0008152 metabolic process; GO:0032879 regulation of localization; GO:1903747 regulation of establishment of protein localization to mitochondrion; GO:0015931 nucleobase-containing compound transport; GO:0043170 macromolecule metabolic process; GO:0008104 protein localization; GO:0006396 RNA processing; GO:0018130 heterocycle biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0050684 regulation of mRNA processing; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0010506 regulation of autophagy; GO:0006611 protein export from nucleus; GO:0006810 transport; GO:0044260 cellular macromolecule metabolic process; GO:0033119 negative regulation of RNA splicing; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051223 regulation of protein transport; GO:0006913 nucleocytoplasmic transport; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0050794 regulation of cellular process; GO:0033120 positive regulation of RNA splicing; GO:0046907 intracellular transport; GO:0051028 mRNA transport; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0051236 establishment of RNA localization; GO:0060341 regulation of cellular localization; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0010628 positive regulation of gene expression; GO:0000375 RNA splicing, via transesterification reactions; GO:0051171 regulation of nitrogen compound metabolic process; GO:0032880 regulation of protein localization; GO:0034613 cellular protein localization; GO:0008380 RNA splicing; GO:0051254 positive regulation of RNA metabolic process; GO:0006403 RNA localization; GO:0006405 RNA export from nucleus; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0043484 regulation of RNA splicing; GO:0045184 establishment of protein localization; GO:1903311 regulation of mRNA metabolic process; GO:1904951 positive regulation of establishment of protein localization; GO:0031325 positive regulation of cellular metabolic process; GO:0051179 localization; GO:0048025 negative regulation of mRNA splicing, via spliceosome; GO:1903827 regulation of cellular protein localization; GO:0051168 nuclear export; GO:0009058 biosynthetic process; GO:0051253 negative regulation of RNA metabolic process; GO:1903312 negative regulation of mRNA metabolic process; GO:1903749 positive regulation of establishment of protein localization to mitochondrion; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0006353 DNA-templated transcription, termination; GO:0071427 mRNA-containing ribonucleoprotein complex export from nucleus; GO:0051649 establishment of localization in cell; GO:0009893 positive regulation of metabolic process; GO:0050657 nucleic acid transport; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0033036 macromolecule localization; GO:0048024 regulation of mRNA splicing, via spliceosome; GO:0010468 regulation of gene expression; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0032386 regulation of intracellular transport; GO:0010605 negative regulation of macromolecule metabolic process; GO:0071166 ribonucleoprotein complex localization; GO:0051050 positive regulation of transport; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0010638 positive regulation of organelle organization; GO:0006351 transcription, DNA-templated; GO:0019222 regulation of metabolic process; GO:0051222 positive regulation of protein transport; GO:0031123 RNA 3'-end processing; GO:0090316 positive regulation of intracellular protein transport; GO:0006725 cellular aromatic compound metabolic process; GO:0031124 mRNA 3'-end processing; GO:1903829 positive regulation of cellular protein localization; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0070201 regulation of establishment of protein localization; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0006886 intracellular protein transport; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0033157 regulation of intracellular protein transport; GO:0009987 cellular process; GO:0006406 mRNA export from nucleus; GO:0006369 termination of RNA polymerase II transcription; GO:0010629 negative regulation of gene expression; GO:0051049 regulation of transport; GO:0032388 positive regulation of intracellular transport; GO:0033043 regulation of organelle organization; GO:0006807 nitrogen compound metabolic process; GO:1903214 regulation of protein targeting to mitochondrion; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0010822 positive regulation of mitochondrion organization; GO:0070727 cellular macromolecule localization; GO:0071426 ribonucleoprotein complex export from nucleus; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:1903146 regulation of mitophagy; GO:0006366 transcription from RNA polymerase II promoter; GO:0010467 gene expression; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0051128 regulation of cellular component organization; GO:0071705 nitrogen compound transport; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0089701 U2AF; GO:0044446 intracellular organelle part; GO:0005684 U2-type spliceosomal complex; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005681 spliceosomal complex; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0005622 intracellular; GO:0044464 cell part; GO:0071010 prespliceosome; GO:0071004 U2-type prespliceosome; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0043234 protein complex; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0000243 commitment complex; GO:0044428 nuclear part; ","GO:0003723 RNA binding; GO:1901265 nucleoside phosphate binding; GO:0030628 pre-mRNA 3'-splice site binding; GO:0070742 C2H2 zinc finger domain binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0003727 single-stranded RNA binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0008187 poly-pyrimidine tract binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0036002 pre-mRNA binding; GO:0019904 protein domain specific binding; GO:0019899 enzyme binding; GO:0036094 small molecule binding; ","K12837","U2AF2; splicing factor U2AF 65 kDa subunit","hsa03040 Spliceosome - Homo sapiens (human); ","IPR000504; IPR012677; ","RNA recognition motif domain; Nucleotide-binding alpha-beta plait domain; \r"]
["P26373","60S ribosomal protein L13 OS=Homo sapiens OX=9606 GN=RPL13","RPL13",24.261,31.813,32.7,8,19,8,0.815,0.902,0.932,1.123,1.11,1.119,1.265,0.028,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0072594 establishment of protein localization to organelle; GO:0006518 peptide metabolic process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0051649 establishment of localization in cell; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0070972 protein localization to endoplasmic reticulum; GO:0006364 rRNA processing; GO:0006413 translational initiation; GO:1901361 organic cyclic compound catabolic process; GO:0033365 protein localization to organelle; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0006412 translation; GO:0016072 rRNA metabolic process; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0072657 protein localization to membrane; GO:0043043 peptide biosynthetic process; GO:0042254 ribosome biogenesis; GO:1901360 organic cyclic compound metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032774 RNA biosynthetic process; GO:0045047 protein targeting to ER; GO:0043603 cellular amide metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0006401 RNA catabolic process; GO:0016070 RNA metabolic process; GO:0019439 aromatic compound catabolic process; GO:1901575 organic substance catabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0019083 viral transcription; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0046907 intracellular transport; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0044267 cellular protein metabolic process; GO:0006613 cotranslational protein targeting to membrane; GO:0048519 negative regulation of biological process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0016032 viral process; GO:0019080 viral gene expression; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0006886 intracellular protein transport; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0034613 cellular protein localization; GO:0009059 macromolecule biosynthetic process; GO:0090150 establishment of protein localization to membrane; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0051179 localization; GO:0009056 catabolic process; GO:0034660 ncRNA metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0005840 ribosome; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0043232 intracellular non-membrane-bounded organelle; GO:0022625 cytosolic large ribosomal subunit; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0015934 large ribosomal subunit; GO:0044391 ribosomal subunit; GO:0005622 intracellular; GO:0044464 cell part; GO:0044445 cytosolic part; GO:1990904 ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0030529 intracellular ribonucleoprotein complex; GO:0044444 cytoplasmic part; GO:0022626 cytosolic ribosome; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0005198 structural molecule activity; GO:0003735 structural constituent of ribosome; ","K02873","RP-L13e; large subunit ribosomal protein L13e","hsa03010 Ribosome - Homo sapiens (human); "]
["P26639","Threonine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=TARS","TARS",83.434,47.725,17.7,12,14,12,0.866,0.844,1.047,1.086,1.08,1.083,1.178,0.131,"cytoplasm\r","GO:0006518 peptide metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0043039 tRNA aminoacylation; GO:0044237 cellular metabolic process; GO:0006435 threonyl-tRNA aminoacylation; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0006418 tRNA aminoacylation for protein translation; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0006412 translation; GO:0009987 cellular process; GO:0043043 peptide biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0016070 RNA metabolic process; GO:0006399 tRNA metabolic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0090304 nucleic acid metabolic process; GO:0044710 single-organism metabolic process; GO:0043038 amino acid activation; GO:0019752 carboxylic acid metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0006082 organic acid metabolic process; GO:0034660 ncRNA metabolic process; GO:0043436 oxoacid metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0015629 actin cytoskeleton; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds; GO:0004829 threonine-tRNA ligase activity; GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0016875 ligase activity, forming carbon-oxygen bonds; GO:0046983 protein dimerization activity; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016874 ligase activity; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0004812 aminoacyl-tRNA ligase activity; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K01868","TARS; threonyl-tRNA synthetase [EC:6.1.1.3]","hsa00970 Aminoacyl-tRNA biosynthesis - Homo sapiens (human); ","IPR018163; IPR002314; IPR012675; IPR006195; IPR012947; IPR033728; IPR012676; IPR004095; IPR004154; ","\"Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain; Aminoacyl-tRNA synthetase, class II (G/ P/ S/T); Beta-grasp domain; Aminoacyl-tRNA synthetase, class II; Threonyl/alanyl tRNA synthetase, SAD; Threonine-tRNA ligase catalytic core domain; TGS-like; TGS; Anticodon-binding; \"\r"]
["P26640","Valine--tRNA ligase OS=Homo sapiens OX=9606 GN=VARS","VARS",140.47,104.22,20.6,21,34,21,0.953,0.954,0.94,1.057,1.012,1.072,1.103,0.0055,"cytoplasm\r","GO:0065008 regulation of biological quality; GO:0006518 peptide metabolic process; GO:0010608 posttranscriptional regulation of gene expression; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0006418 tRNA aminoacylation for protein translation; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0006412 translation; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0043043 peptide biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0016070 RNA metabolic process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0006438 valyl-tRNA aminoacylation; GO:0090304 nucleic acid metabolic process; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006082 organic acid metabolic process; GO:0043436 oxoacid metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0044267 cellular protein metabolic process; GO:0043039 tRNA aminoacylation; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006448 regulation of translational elongation; GO:0006450 regulation of translational fidelity; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0034248 regulation of cellular amide metabolic process; GO:0006399 tRNA metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0006417 regulation of translation; GO:0051246 regulation of protein metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0043038 amino acid activation; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0034660 ncRNA metabolic process; GO:0065007 biological regulation; GO:1901564 organonitrogen compound metabolic process; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005829 cytosol; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044444 cytoplasmic part; ","GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds; GO:0052689 carboxylic ester hydrolase activity; GO:1901265 nucleoside phosphate binding; GO:0016875 ligase activity, forming carbon-oxygen bonds; GO:0016874 ligase activity; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0004832 valine-tRNA ligase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0004812 aminoacyl-tRNA ligase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0002161 aminoacyl-tRNA editing activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; ","K01873","VARS; valyl-tRNA synthetase [EC:6.1.1.9]","hsa00970 Aminoacyl-tRNA biosynthesis - Homo sapiens (human); ","IPR004046; IPR009080; IPR014729; IPR009008; IPR013155; IPR010987; IPR002300; IPR033705; ","\"Glutathione S-transferase, C-terminal; Aminoacyl-tRNA synthetase, class Ia, anticodon-binding; Rossmann-like alpha/beta/alpha sandwich fold; Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain; Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding; Glutathione S-transferase, C-terminal-like; Aminoacyl-tRNA synthetase, class Ia; Valyl tRNA synthetase, anticodon-binding domain; \"\r"]
["P26927","Hepatocyte growth factor-like protein OS=Homo sapiens OX=9606 GN=MST1","MST1",80.319,25.402,10.4,6,6,6,0.916,0.995,0.984,1.135,1,0.977,1.075,0.255,"extracellular\r","GO:0044700 single organism signaling; GO:0045859 regulation of protein kinase activity; GO:0050794 regulation of cellular process; GO:0043255 regulation of carbohydrate biosynthetic process; GO:0006111 regulation of gluconeogenesis; GO:0007166 cell surface receptor signaling pathway; GO:0060255 regulation of macromolecule metabolic process; GO:0048012 hepatocyte growth factor receptor signaling pathway; GO:0031399 regulation of protein modification process; GO:0044699 single-organism process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:0010906 regulation of glucose metabolic process; GO:0071704 organic substance metabolic process; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0009889 regulation of biosynthetic process; GO:0051338 regulation of transferase activity; GO:0006508 proteolysis; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009987 cellular process; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0010677 negative regulation of cellular carbohydrate metabolic process; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0010675 regulation of cellular carbohydrate metabolic process; GO:0045721 negative regulation of gluconeogenesis; GO:0001932 regulation of protein phosphorylation; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0044238 primary metabolic process; GO:0023052 signaling; GO:0031323 regulation of cellular metabolic process; GO:0006109 regulation of carbohydrate metabolic process; GO:0009892 negative regulation of metabolic process; GO:0009890 negative regulation of biosynthetic process; GO:0045912 negative regulation of carbohydrate metabolic process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:2000479 regulation of cAMP-dependent protein kinase activity; GO:0051246 regulation of protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0019220 regulation of phosphate metabolic process; GO:0043549 regulation of kinase activity; GO:0065007 biological regulation; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:0004252 serine-type endopeptidase activity; GO:0004175 endopeptidase activity; GO:0008233 peptidase activity; GO:0030971 receptor tyrosine kinase binding; GO:1990782 protein tyrosine kinase binding; GO:0005102 receptor binding; GO:0003824 catalytic activity; GO:0017171 serine hydrolase activity; GO:0005488 binding; GO:0019901 protein kinase binding; GO:0008236 serine-type peptidase activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0019900 kinase binding; GO:0019899 enzyme binding; ",{"$nulls":3},"IPR009003; IPR003609; IPR000001; IPR001254; IPR013806; ","\"Peptidase S1, PA clan; PAN/Apple domain; Kringle; Serine proteases, trypsin domain; Kringle-like fold; \"\r"]
["P27144","Adenylate kinase 4, mitochondrial OS=Homo sapiens OX=9606 GN=AK4","AK4",25.268,21.39,32.3,7,9,7,1.02,1.038,1.045,0.988,0.961,0.987,0.946,0.0088,"mitochondria\r","GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0048732 gland development; GO:0006165 nucleoside diphosphate phosphorylation; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0007420 brain development; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0046939 nucleotide phosphorylation; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0008152 metabolic process; GO:1901068 guanosine-containing compound metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0060322 head development; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0018130 heterocycle biosynthetic process; GO:0046940 nucleoside monophosphate phosphorylation; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0032501 multicellular organismal process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0090407 organophosphate biosynthetic process; GO:0048513 animal organ development; GO:0042221 response to chemical; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0007417 central nervous system development; GO:0044710 single-organism metabolic process; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0048856 anatomical structure development; GO:0046039 GTP metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0016310 phosphorylation; GO:0044707 single-multicellular organism process; GO:0009165 nucleotide biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0009259 ribonucleotide metabolic process; GO:0015949 nucleobase-containing small molecule interconversion; GO:0009142 nucleoside triphosphate biosynthetic process; GO:0050896 response to stimulus; GO:0046033 AMP metabolic process; GO:0071704 organic substance metabolic process; GO:0042493 response to drug; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:1901135 carbohydrate derivative metabolic process; GO:0061008 hepaticobiliary system development; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009119 ribonucleoside metabolic process; GO:0009987 cellular process; GO:0009132 nucleoside diphosphate metabolic process; GO:0046034 ATP metabolic process; GO:0044711 single-organism biosynthetic process; GO:0048731 system development; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0006163 purine nucleotide metabolic process; GO:0044249 cellular biosynthetic process; GO:0046128 purine ribonucleoside metabolic process; GO:0001889 liver development; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0044767 single-organism developmental process; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0009123 nucleoside monophosphate metabolic process; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0044429 mitochondrial part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:1901265 nucleoside phosphate binding; GO:0004017 adenylate kinase activity; GO:0019205 nucleobase-containing compound kinase activity; GO:0019201 nucleotide kinase activity; GO:0016776 phosphotransferase activity, phosphate group as acceptor; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0050145 nucleoside phosphate kinase activity; GO:0016301 kinase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0004550 nucleoside diphosphate kinase activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0046899 nucleoside triphosphate adenylate kinase activity; GO:0032555 purine ribonucleotide binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K00939","adk; adenylate kinase [EC:2.7.4.3]","hsa00730 Thiamine metabolism - Homo sapiens (human); hsa00230 Purine metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR007862; IPR027417; ","\"Adenylate kinase, active site lid domain; P-loop containing nucleoside triphosphate hydrolase; \"\r"]
["P27361","Mitogen-activated protein kinase 3 OS=Homo sapiens OX=9606 GN=MAPK3","MAPK3",43.135,12.339,18.7,7,10,6,1,0.934,1.018,0.969,1.07,1.023,1.037,0.401,"cytoplasm\r",{"$cut":{"chars":22098,"head":"GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0032872 regulation of stress-activated MAPK cascade; GO:0048732 gland development; GO:0061308 cardiac neural crest cell development involved in heart development; GO:0030323 respiratory tube development; GO:0010608 posttranscriptional regulation of gene expression; GO:0030878 thyroid gland development; GO:0009891 positive regulation of biosynthetic process; GO:0018212 peptidyl-tyrosine modification; GO:0044255 cellular lipid metabolic process; GO:0032091 negative regulation of protein binding; GO:0070555 response to interleukin-1; GO:0031347 regulation of defense response; GO:0044237 cellular metabolic process; GO:0009607 response to biotic stimulus; GO:1905269 positive regulation of chromatin organization; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0008152 metabolic process; GO:0030509 BMP signaling pathway; GO:0065003 macromolecular complex assembly; GO:0044093 positive regulation of molecular function; GO:0051493 regulation of cytoskeleton organization; GO:2000656 regulation of apolipoprotein binding; GO:0009790 embryo development; GO:0006606 protein import into nucleus; GO:0048598 embryonic morphogenesis; GO:0090596 sensory organ morphogenesis; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0071214 cellular response to abiotic stimulus; GO:0030168 platelet activation; GO:0051054 positive regulation of DNA metabolic process; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0002520 immune system development; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0006935 chemotaxis; GO:0010506 regulation of autophagy; GO:0071396 cellular response to lipid; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0016241 regulation of macroautophagy; GO:0006810 transport; GO:0031279 regulation of cyclase activity; GO:0000165 MAPK cascade; GO:0010243 response to organonitrogen compound; GO:0042063 gliogenesis; GO:0080135 regulation of cellular response to stress; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0016239 positive regulation of macroautophagy; GO:0006913 nucleocytoplasmic transport; GO:0043436 oxoacid metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0033559 unsaturated fatty acid metabolic process; GO:0072359 circulatory system development; GO:0016310 phosphorylation; GO:0044707 single-multicellular organism process; GO:0019369 arachidonic acid metabolic process; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:1901700 response to oxygen-containing compound; GO:0009653 anatomical structure morphogenesis; GO:1901985 positive regulation of protein acetylation; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0060541 respiratory system development; GO:0009889 regulation of biosynthetic process; GO:0009896 positive regulation of catabolic process; GO:2000641 regulation of early endosome to late endosome transport; GO:0044744 protein targeting to nucleus; GO:1902680 positive regulation of RNA biosynthetic process; GO:1902580 single-organism cellular localization; GO:0038093 Fc receptor signaling pathway; GO:0034613 cellular protein localization; GO:0050778 positive regulation of immune response; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0023014 signal transduction by protein phosphorylation; GO:0006950 response to stress; GO:0032496 response to lipopolysaccharide; GO:0060440 trachea formation; GO:0002376 immune system process; GO:0032101 regulation of response to external stimulus; GO:0010033 response to organic substance; GO:2000278 regulation of DNA biosynthetic process; GO:1901576 organic substance biosynthetic process; G"}},"GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0098857 membrane microdomain; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031143 pseudopodium; GO:0005769 early endosome; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0098590 plasma membrane region; GO:0005925 focal adhesion; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0098589 membrane region; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0030055 cell-substrate junction; GO:0045121 membrane raft; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0042995 cell projection; GO:0005770 late endosome; GO:0005635 nuclear envelope; GO:0043232 intracellular non-membrane-bounded organelle; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0005901 caveola; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0044853 plasma membrane raft; GO:0031975 envelope; GO:0005794 Golgi apparatus; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0097110 scaffold protein binding; GO:0005515 protein binding; GO:0004672 protein kinase activity; GO:0004702 signal transducer, downstream of receptor, with serine/threonine kinase activity; GO:0004871 signal transducer activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016301 kinase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0001784 phosphotyrosine binding; GO:0019902 phosphatase binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0045309 protein phosphorylated amino acid binding; GO:0000166 nucleotide binding; GO:0004707 MAP kinase activity; GO:0051219 phosphoprotein binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0005057 signal transducer activity, downstream of receptor; GO:0004674 protein serine/threonine kinase activity; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019899 enzyme binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0036094 small molecule binding; ","K04371","MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]","hsa05152 Tuberculosis - Homo sapiens (human); hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human); hsa04662 B cell receptor signaling pathway - Homo sapiens (human); hsa05220 Chronic myeloid leukemia - Homo sapiens (human); hsa04014 Ras signaling pathway - Homo sapiens (human); hsa04150 mTOR signaling pathway - Homo sapiens (human); hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa05206 MicroRNAs in cancer - Homo sapiens (human); hsa05145 Toxoplasmosis - Homo sapiens (human); hsa05164 Influenza A - Homo sapiens (human); hsa04960 Aldosterone-regulated sodium reabsorption - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa04934 Cushing's syndrome - Homo sapiens (human); hsa04933 AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human); hsa04659 Th17 cell differentiation - Homo sapiens (human); hsa04611 Platelet activation - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa04917 Prolactin signaling pathway - Homo sapiens (human); hsa05161 Hepatitis B - Homo sapiens (human); hsa04930 Type II diabetes mellitus - Homo sapiens (human); hsa05215 Prostate cancer - Homo sapiens (human); hsa01521 EGFR tyrosine kinase inhibitor resistance - Homo sapiens (human); hsa04914 Progesterone-mediated oocyte maturation - Homo sapiens (human); hsa04725 Cholinergic synapse - Homo sapiens (human); hsa05142 Chagas disease (American trypanosomiasis) - Homo sapiens (human); hsa04921 Oxytocin signaling pathway - Homo sapiens (human); hsa04218 Cellular senescence - Homo sapiens (human); hsa04722 Neurotrophin signaling pathway - Homo sapiens (human); hsa04371 Apelin signaling pathway - Homo sapiens (human); hsa05160 Hepatitis C - Homo sapiens (human); hsa04916 Melanogenesis - Homo sapiens (human); hsa04270 Vascular smooth muscle contraction - Homo sapiens (human); hsa05167 Kaposi's sarcoma-associated herpesvirus infection - Homo sapiens (human); hsa04350 TGF-beta signaling pathway - Homo sapiens (human); hsa04010 MAPK signaling pathway - Homo sapiens (human); hsa01524 Platinum drug resistance - Homo sapiens (human); hsa05219 Bladder cancer - Homo sapiens (human); hsa04664 Fc epsilon RI signaling pathway - Homo sapiens (human); hsa04657 IL-17 signaling pathway - Homo sapiens (human); hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human); hsa04540 Gap junction - Homo sapiens (human); hsa04912 GnRH signaling pathway - Homo sapiens (human); hsa04668 TNF signaling pathway - Homo sapiens (human); hsa05020 Prion diseases - Homo sapiens (human); hsa05203 Viral carcinogenesis - Homo sapiens (human); hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human); hsa04730 Long-term depression - Homo sapiens (human); hsa05133 Pertussis - Homo sapiens (human); hsa05226 Gastric cancer - Homo sapiens (human); hsa04720 Long-term potentiation - Homo sapiens (human); hsa04713 Circadian entrainment - Homo sapiens (human); hsa04928 Parathyroid hormone synthesis, secretion and action - Homo sapiens (human); hsa05218 Melanoma - Homo sapiens (human); hsa05212 Pancreatic cancer - Homo sapiens (human); hsa04550 Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human); hsa04015 Rap1 signaling pathway - Homo sapiens (human); hsa04072 Phospholipase D signaling pathway - Homo sapiens (human); hsa04650 Natural killer cell mediated cytotoxicity - Homo sapiens (human); hsa05221 Acute myeloid leukemia - Homo sapiens (human); hsa04625 C-type lectin receptor signaling pathway - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa05230 Central carbon metabolism in cancer - Homo sapiens (human); hsa04724 Glutamatergic synapse - Homo sapiens (human); hsa05131 Shigellosis - Homo sapiens (human); hsa04140 Autophagy - animal - Homo sapiens (human); hsa04114 Oocyte meiosis - Homo sapiens (human); hsa04380 Osteoclast differentiation - Homo sapiens (human); hsa04071 Sphingolipid signaling pathway - Homo sapiens (human); hsa05213 Endometrial cancer - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa05224 Breast cancer - Homo sapiens (human); hsa04520 Adherens junction - Homo sapiens (human); hsa01522 Endocrine resistance - Homo sapiens (human); hsa05034 Alcoholism - Homo sapiens (human); hsa05210 Colorectal cancer - Homo sapiens (human); hsa04915 Estrogen signaling pathway - Homo sapiens (human); hsa05010 Alzheimer's disease - Homo sapiens (human); hsa05216 Thyroid cancer - Homo sapiens (human); hsa05132 Salmonella infection - Homo sapiens (human); hsa05231 Choline metabolism in cancer - Homo sapiens (human); hsa04620 Toll-like receptor signaling pathway - Homo sapiens (human); hsa04210 Apoptosis - Homo sapiens (human); hsa04370 VEGF signaling pathway - Homo sapiens (human); hsa05140 Leishmaniasis - Homo sapiens (human); hsa04910 Insulin signaling pathway - Homo sapiens (human); hsa05211 Renal cell carcinoma - Homo sapiens (human); hsa05225 Hepatocellular carcinoma - Homo sapiens (human); hsa04024 cAMP signaling pathway - Homo sapiens (human); hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa04660 T cell receptor signaling pathway - Homo sapiens (human); hsa04726 Serotonergic synapse - Homo sapiens (human); hsa04658 Th1 and Th2 cell differentiation - Homo sapiens (human); hsa04062 Chemokine signaling pathway - Homo sapiens (human); hsa05223 Non-small cell lung cancer - Homo sapiens (human); hsa04666 Fc gamma R-mediated phagocytosis - Homo sapiens (human); hsa04066 HIF-1 signaling pathway - Homo sapiens (human); hsa05214 Glioma - Homo sapiens (human); hsa04068 FoxO signaling pathway - Homo sapiens (human); hsa04012 ErbB signaling pathway - Homo sapiens (human); hsa04360 Axon guidance - Homo sapiens (human); hsa04926 Relaxin signaling pathway - Homo sapiens (human); ","IPR000719; IPR011009; ","Protein kinase domain; Protein kinase-like domain; \r"]
["P27482","Calmodulin-like protein 3 OS=Homo sapiens OX=9606 GN=CALML3","CALML3",16.891,87.353,75.8,12,18,11,0.905,0.869,0.903,1.109,1.07,1.097,1.224,2.81E-4,"nucleus\r",null,"GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0005509 calcium ion binding; GO:0005488 binding; GO:0043167 ion binding; ","K02183","CALM; calmodulin","hsa05152 Tuberculosis - Homo sapiens (human); hsa04015 Rap1 signaling pathway - Homo sapiens (human); hsa04625 C-type lectin receptor signaling pathway - Homo sapiens (human); hsa04014 Ras signaling pathway - Homo sapiens (human); hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human); hsa04924 Renin secretion - Homo sapiens (human); hsa04970 Salivary secretion - Homo sapiens (human); hsa04114 Oocyte meiosis - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa04070 Phosphatidylinositol signaling system - Homo sapiens (human); hsa04922 Glucagon signaling pathway - Homo sapiens (human); hsa05034 Alcoholism - Homo sapiens (human); hsa04971 Gastric acid secretion - Homo sapiens (human); hsa04744 Phototransduction - Homo sapiens (human); hsa04915 Estrogen signaling pathway - Homo sapiens (human); hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04921 Oxytocin signaling pathway - Homo sapiens (human); hsa04218 Cellular senescence - Homo sapiens (human); hsa04728 Dopaminergic synapse - Homo sapiens (human); hsa04371 Apelin signaling pathway - Homo sapiens (human); hsa04722 Neurotrophin signaling pathway - Homo sapiens (human); hsa05031 Amphetamine addiction - Homo sapiens (human); hsa04910 Insulin signaling pathway - Homo sapiens (human); hsa04916 Melanogenesis - Homo sapiens (human); hsa04020 Calcium signaling pathway - Homo sapiens (human); hsa05167 Kaposi's sarcoma-associated herpesvirus infection - Homo sapiens (human); hsa04270 Vascular smooth muscle contraction - Homo sapiens (human); hsa04024 cAMP signaling pathway - Homo sapiens (human); hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human); hsa04750 Inflammatory mediator regulation of TRP channels - Homo sapiens (human); hsa04925 Aldosterone synthesis and secretion - Homo sapiens (human); hsa04740 Olfactory transduction - Homo sapiens (human); hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human); hsa04912 GnRH signaling pathway - Homo sapiens (human); hsa05214 Glioma - Homo sapiens (human); hsa05133 Pertussis - Homo sapiens (human); hsa04720 Long-term potentiation - Homo sapiens (human); hsa04713 Circadian entrainment - Homo sapiens (human); ","IPR002048; IPR011992; ","EF-hand domain; EF-hand domain pair; \r"]
["P27635","60S ribosomal protein L10 OS=Homo sapiens OX=9606 GN=RPL10","RPL10",24.604,8.4179,14,3,6,3,0.857,0.933,0.829,1.186,1.161,1.031,1.29,0.0106,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0072594 establishment of protein localization to organelle; GO:0006518 peptide metabolic process; GO:0022618 ribonucleoprotein complex assembly; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0042273 ribosomal large subunit biogenesis; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0051649 establishment of localization in cell; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0000027 ribosomal large subunit assembly; GO:0071826 ribonucleoprotein complex subunit organization; GO:0070972 protein localization to endoplasmic reticulum; GO:0022607 cellular component assembly; GO:0006364 rRNA processing; GO:0065003 macromolecular complex assembly; GO:0006413 translational initiation; GO:1901361 organic cyclic compound catabolic process; GO:0033365 protein localization to organelle; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0006412 translation; GO:0016072 rRNA metabolic process; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0072657 protein localization to membrane; GO:0043043 peptide biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0042254 ribosome biogenesis; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032774 RNA biosynthetic process; GO:0045047 protein targeting to ER; GO:0043603 cellular amide metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0016070 RNA metabolic process; GO:0006401 RNA catabolic process; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0019083 viral transcription; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0044267 cellular protein metabolic process; GO:0006613 cotranslational protein targeting to membrane; GO:0048519 negative regulation of biological process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0070925 organelle assembly; GO:0006139 nucleobase-containing compound metabolic process; GO:0016032 viral process; GO:0019080 viral gene expression; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0006886 intracellular protein transport; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0034613 cellular protein localization; GO:0009059 macromolecule biosynthetic process; GO:0090150 establishment of protein localization to membrane; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0034622 cellular macromolecular complex assembly; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0042255 ribosome assembly; GO:0043933 macromolecular complex subunit organization; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006996 organelle organization; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0051179 localization; GO:0009056 catabolic process; GO:0034660 ncRNA metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0071840 cellular component organization or biogenesis; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; ","GO:0005840 ribosome; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0043232 intracellular non-membrane-bounded organelle; GO:0022625 cytosolic large ribosomal subunit; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0012505 endomembrane system; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0015934 large ribosomal subunit; GO:0044391 ribosomal subunit; GO:0005622 intracellular; GO:0044464 cell part; GO:0044445 cytosolic part; GO:1990904 ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0030529 intracellular ribonucleoprotein complex; GO:0044444 cytoplasmic part; GO:0022626 cytosolic ribosome; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0005198 structural molecule activity; GO:0003735 structural constituent of ribosome; ","K02866","RP-L10e; large subunit ribosomal protein L10e","hsa03010 Ribosome - Homo sapiens (human); ","IPR016180; ","Ribosomal protein L10e/L16; \r"]
["P27694","Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1","RPA1",68.137,64.335,26.3,15,20,15,0.992,1.034,0.952,1.04,1.028,1.026,1.039,0.185,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion; GO:0023051 regulation of signaling; GO:0006289 nucleotide-excision repair; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0051130 positive regulation of cellular component organization; GO:0008152 metabolic process; GO:0010646 regulation of cell communication; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0051606 detection of stimulus; GO:0019985 translesion synthesis; GO:0044770 cell cycle phase transition; GO:0031334 positive regulation of protein complex assembly; GO:0043170 macromolecule metabolic process; GO:0033365 protein localization to organelle; GO:0006261 DNA-dependent DNA replication; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0006310 DNA recombination; GO:0071824 protein-DNA complex subunit organization; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0065004 protein-DNA complex assembly; GO:0000722 telomere maintenance via recombination; GO:0006298 mismatch repair; GO:0050789 regulation of biological process; GO:0043254 regulation of protein complex assembly; GO:0080135 regulation of cellular response to stress; GO:0090304 nucleic acid metabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0042276 error-prone translesion synthesis; GO:1900034 regulation of cellular response to heat; GO:0032200 telomere organization; GO:0006297 nucleotide-excision repair, DNA gap filling; GO:0006312 mitotic recombination; GO:0090305 nucleic acid phosphodiester bond hydrolysis; GO:1901362 organic cyclic compound biosynthetic process; GO:0034502 protein localization to chromosome; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0033554 cellular response to stress; GO:0006260 DNA replication; GO:0006725 cellular aromatic compound metabolic process; GO:0006283 transcription-coupled nucleotide-excision repair; GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion; GO:0006259 DNA metabolic process; GO:0006302 double-strand break repair; GO:0044087 regulation of cellular component biogenesis; GO:0000731 DNA synthesis involved in DNA repair; GO:0080134 regulation of response to stress; GO:0050896 response to stimulus; GO:0042769 DNA damage response, detection of DNA damage; GO:1903047 mitotic cell cycle process; GO:0060249 anatomical structure homeostasis; GO:0033683 nucleotide-excision repair, DNA incision; GO:0006293 nucleotide-excision repair, preincision complex stabilization; GO:0071704 organic substance metabolic process; GO:0006301 postreplication repair; GO:0042592 homeostatic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901796 regulation of signal transduction by p53 class mediator; GO:0070987 error-free translesion synthesis; GO:0071897 DNA biosynthetic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0000082 G1/S transition of mitotic cell cycle; GO:0034613 cellular protein localization; GO:0009059 macromolecule biosynthetic process; GO:0000724 double-strand break repair via homologous recombination; GO:0009987 cellular process; GO:0009966 regulation of signal transduction; GO:0044772 mitotic cell cycle phase transition; GO:0034622 cellular macromolecular complex assembly; GO:0006284 base-excision repair; GO:1902531 regulation of intracellular signal transduction; GO:0006950 response to stress; GO:0044843 cell cycle G1/S phase transition; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:0036297 interstrand cross-link repair; GO:1901576 organic substance biosynthetic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0006974 cellular response to DNA damage stimulus; GO:0043933 macromolecular complex subunit organization; GO:0051641 cellular localization; GO:0000725 recombinational repair; GO:0070727 cellular macromolecule localization; GO:0006281 DNA repair; GO:0051276 chromosome organization; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0006996 organelle organization; GO:0006294 nucleotide-excision repair, preincision complex assembly; GO:0022402 cell cycle process; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0007049 cell cycle; GO:0044089 positive regulation of cellular component biogenesis; GO:0000723 telomere maintenance; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0000784 nuclear chromosome, telomeric region; GO:0000781 chromosome, telomeric region; GO:0043601 nuclear replisome; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0016605 PML body; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044454 nuclear chromosome part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0030894 replisome; GO:0043227 membrane-bounded organelle; GO:0032993 protein-DNA complex; GO:0044451 nucleoplasm part; GO:0005662 DNA replication factor A complex; GO:0043233 organelle lumen; GO:0005657 replication fork; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0043596 nuclear replication fork; GO:0043226 organelle; GO:0098687 chromosomal region; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0000228 nuclear chromosome; GO:0043234 protein complex; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003677 DNA binding; GO:0005488 binding; GO:0043167 ion binding; GO:0003676 nucleic acid binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0003697 single-stranded DNA binding; GO:0005515 protein binding; GO:0003684 damaged DNA binding; ","K07466","RFA1; replication factor A1","hsa03460 Fanconi anemia pathway - Homo sapiens (human); hsa03430 Mismatch repair - Homo sapiens (human); hsa03440 Homologous recombination - Homo sapiens (human); hsa03420 Nucleotide excision repair - Homo sapiens (human); hsa03030 DNA replication - Homo sapiens (human); ","IPR031657; IPR012340; IPR004365; IPR013955; IPR007199; ","\"Replication protein A, OB domain; Nucleic acid-binding, OB-fold; OB-fold nucleic acid binding domain, AA-tRNA synthetase-type; Replication factor A, C-terminal; Replication factor-A protein 1, N-terminal; \"\r"]
["P27797","Calreticulin OS=Homo sapiens OX=9606 GN=CALR","CALR",48.141,186.27,57.3,22,53,22,0.975,0.994,1.004,1.006,0.983,1.007,1.008,0.544,"endoplasmic reticulum\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0010941 regulation of cell death; GO:0022414 reproductive process; GO:0010608 posttranscriptional regulation of gene expression; GO:0009891 positive regulation of biosynthetic process; GO:0010564 regulation of cell cycle process; GO:1901224 positive regulation of NIK/NF-kappaB signaling; GO:0008152 metabolic process; GO:0065003 macromolecular complex assembly; GO:0030522 intracellular receptor signaling pathway; GO:0055065 metal ion homeostasis; GO:0030518 intracellular steroid hormone receptor signaling pathway; GO:0051716 cellular response to stimulus; GO:0051054 positive regulation of DNA metabolic process; GO:0080090 regulation of primary metabolic process; GO:0060537 muscle tissue development; GO:0048699 generation of neurons; GO:1900026 positive regulation of substrate adhesion-dependent cell spreading; GO:0044763 single-organism cellular process; GO:0034249 negative regulation of cellular amide metabolic process; GO:0006611 protein export from nucleus; GO:0051704 multi-organism process; GO:0071396 cellular response to lipid; GO:0006874 cellular calcium ion homeostasis; GO:0010811 positive regulation of cell-substrate adhesion; GO:0002502 peptide antigen assembly with MHC class I protein complex; GO:0006810 transport; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0042921 glucocorticoid receptor signaling pathway; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0045665 negative regulation of neuron differentiation; GO:0006913 nucleocytoplasmic transport; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0010721 negative regulation of cell development; GO:0048609 multicellular organismal reproductive process; GO:0002687 positive regulation of leukocyte migration; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0000003 reproduction; GO:0072359 circulatory system development; GO:0044707 single-multicellular organism process; GO:1901700 response to oxygen-containing compound; GO:0048519 negative regulation of biological process; GO:0045892 negative regulation of transcription, DNA-templated; GO:0042493 response to drug; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:2000145 regulation of cell motility; GO:0009889 regulation of biosynthetic process; GO:0061061 muscle structure development; GO:0034613 cellular protein localization; GO:0048878 chemical homeostasis; GO:0006986 response to unfolded protein; GO:0030100 regulation of endocytosis; GO:0006950 response to stress; GO:0045785 positive regulation of cell adhesion; GO:0051270 regulation of cellular component movement; GO:0051960 regulation of nervous system development; GO:0060284 regulation of cell development; GO:0050766 positive regulation of phagocytosis; GO:0032101 regulation of response to external stimulus; GO:0002376 immune system process; GO:0048284 organelle fusion; GO:0010033 response to organic substance; GO:0034248 regulation of cellular amide metabolic process; GO:0009890 negative regulation of biosynthetic process; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0031647 regulation of protein stability; GO:0048387 negative regulation of retinoic acid receptor signaling pathway; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:0050821 protein stabilization; GO:0008284 positive regulation of cell proliferation; GO:0051093 negative regulation of developmental process; GO:0009968 negative regulation of signal transduction; GO:0040017 positive regulation of locomotion; GO:0023051 regulation of signaling; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0051168 nuclear export; GO:0071383 cellular response to steroid hormone stimulus; GO:0051253 negative regulation of RNA metabolic process; GO:0030968 endoplasmic reticulum unfolded protein response; GO:2001141 regulation of RNA biosynthetic process; GO:0051783 regulation of nuclear division; GO:0007165 signal transduction; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0033036 macromolecule localization; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0051726 regulation of cell cycle; GO:0010226 response to lithium ion; GO:0031326 regulation of cellular biosynthetic process; GO:0098771 inorganic ion homeostasis; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0010038 response to metal ion; GO:2000241 regulation of reproductive process; GO:0051052 regulation of DNA metabolic process; GO:0045664 regulation of neuron differentiation; GO:1902679 negative regulation of RNA biosynthetic process; GO:0070271 protein complex biogenesis; GO:0014706 striated muscle tissue development; GO:0016043 cellular component organization; GO:0045786 negative regulation of cell cycle; GO:0048738 cardiac muscle tissue development; GO:0035967 cellular response to topologically incorrect protein; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0010770 positive regulation of cell morphogenesis involved in differentiation; GO:0030865 cortical cytoskeleton organization; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0033993 response to lipid; GO:0030154 cell differentiation; GO:0002690 positive regulation of leukocyte chemotaxis; GO:0051961 negative regulation of nervous system development; GO:0055080 cation homeostasis; GO:0023056 positive regulation of signaling; GO:0006886 intracellular protein transport; GO:0051235 maintenance of location; GO:0010647 positive regulation of cell communication; GO:0043623 cellular protein complex assembly; GO:0045595 regulation of cell differentiation; GO:0051146 striated muscle cell differentiation; GO:0034622 cellular macromolecular complex assembly; GO:0006355 regulation of transcription, DNA-templated; GO:0048232 male gamete generation; GO:0010629 negative regulation of gene expression; GO:0051049 regulation of transport; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:0033043 regulation of organelle organization; GO:0044802 single-organism membrane organization; GO:0016050 vesicle organization; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0050920 regulation of chemotaxis; GO:0009755 hormone-mediated signaling pathway; GO:0043933 macromolecular complex subunit organization; GO:0019882 antigen processing and presentation; GO:0071495 cellular response to endogenous stimulus; GO:0044703 multi-organism reproductive process; GO:0002684 positive regulation of immune system process; GO:0042692 muscle cell differentiation; GO:0051248 negative regulation of protein metabolic process; GO:0010467 gene expression; GO:0031327 negative regulation of cellular biosynthetic process; GO:0034504 protein localization to nucleus; GO:0043401 steroid hormone mediated signaling pathway; GO:0042981 regulation of apoptotic process; GO:0050767 regulation of neurogenesis; GO:0071840 cellular component organization or biogenesis; GO:1901654 response to ketone; GO:0060627 regulation of vesicle-mediated transport; GO:1990668 vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane; GO:0030335 positive regulation of cell migration; GO:0065008 regulation of biological quality; GO:0051169 nuclear transport; GO:0071157 negative regulation of cell cycle arrest; GO:0015031 protein transport; GO:0030036 actin cytoskeleton organization; GO:0035966 response to topologically incorrect protein; GO:0007507 heart development; GO:0032879 regulation of localization; GO:0044702 single organism reproductive process; GO:0048545 response to steroid hormone; GO:2000508 regulation of dendritic cell chemotaxis; GO:0009719 response to endogenous stimulus; GO:0050921 positive regulation of chemotaxis; GO:0033365 protein localization to organelle; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0044801 single-organism membrane fusion; GO:0008104 protein localization; GO:0007399 nervous system development; GO:0014070 response to organic cyclic compound; GO:0019953 sexual reproduction; GO:0000122 negative regulation of transcription from RNA polymerase II promoter; GO:0061025 membrane fusion; GO:0090398 cellular senescence; GO:0051272 positive regulation of cellular component movement; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0050768 negative regulation of neurogenesis; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0010948 negative regulation of cell cycle process; GO:0007569 cell aging; GO:0032269 negative regulation of cellular protein metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006906 vesicle fusion; GO:0002396 MHC protein complex assembly; GO:0002682 regulation of immune system process; GO:0002685 regulation of leukocyte migration; GO:0051094 positive regulation of developmental process; GO:0036500 ATF6-mediated unfolded protein response; GO:0050794 regulation of cellular process; GO:0090174 organelle membrane fusion; GO:0033554 cellular response to stress; GO:0046907 intracellular transport; GO:0042127 regulation of cell proliferation; GO:0006275 regulation of DNA replication; GO:0034976 response to endoplasmic reticulum stress; GO:0043067 regulation of programmed cell death; GO:0017148 negative regulation of translation; GO:0032355 response to estradiol; GO:2000147 positive regulation of cell motility; GO:0048523 negative regulation of cellular process; GO:0033144 negative regulation of intracellular steroid hormone receptor signaling pathway; GO:0045597 positive regulation of cell differentiation; GO:0051239 regulation of multicellular organismal process; GO:0055007 cardiac muscle cell differentiation; GO:0010628 positive regulation of gene expression; GO:0045740 positive regulation of DNA replication; GO:1900024 regulation of substrate adhesion-dependent cell spreading; GO:0051171 regulation of nitrogen compound metabolic process; GO:0006898 receptor-mediated endocytosis; GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0009966 regulation of signal transduction; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0006461 protein complex assembly; GO:0045787 positive regulation of cell cycle; GO:0002501 peptide antigen assembly with MHC protein complex; GO:1902531 regulation of intracellular signal transduction; GO:0035051 cardiocyte differentiation; GO:1901222 regulation of NIK/NF-kappaB signaling; GO:0007283 spermatogenesis; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0030334 regulation of cell migration; GO:0071702 organic substance transport; GO:0071407 cellular response to organic cyclic compound; GO:0044238 primary metabolic process; GO:0006984 ER-nucleus signaling pathway; GO:0009892 negative regulation of metabolic process; GO:0030155 regulation of cell adhesion; GO:0045184 establishment of protein localization; GO:0006873 cellular ion homeostasis; GO:0030029 actin filament-based process; GO:0061024 membrane organization; GO:0031328 positive regulation of cellular biosynthetic process; GO:0071248 cellular response to metal ion; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0010810 regulation of cell-substrate adhesion; GO:0050793 regulation of developmental process; GO:0051445 regulation of meiotic cell cycle; GO:0072503 cellular divalent inorganic cation homeostasis; GO:0048385 regulation of retinoic acid receptor signaling pathway; GO:0061077 chaperone-mediated protein folding; GO:1902533 positive regulation of intracellular signal transduction; GO:0051241 negative regulation of multicellular organismal process; GO:0022008 neurogenesis; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0006457 protein folding; GO:0010646 regulation of cell communication; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0032103 positive regulation of response to external stimulus; GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I; GO:0010035 response to inorganic substance; GO:0010720 positive regulation of cell development; GO:0045596 negative regulation of cell differentiation; GO:0050764 regulation of phagocytosis; GO:0071285 cellular response to lithium ion; GO:0070887 cellular response to chemical stimulus; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0071822 protein complex subunit organization; GO:0009888 tissue development; GO:0030866 cortical actin cytoskeleton organization; GO:0050801 ion homeostasis; GO:0055074 calcium ion homeostasis; GO:0048002 antigen processing and presentation of peptide antigen; GO:0002688 regulation of leukocyte chemotaxis; GO:0048522 positive regulation of cellular process; GO:0019725 cellular homeostasis; GO:0033574 response to testosterone; GO:0051050 positive regulation of transport; GO:1902589 single-organism organelle organization; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0051208 sequestering of calcium ion; GO:0032268 regulation of cellular protein metabolic process; GO:0032870 cellular response to hormone stimulus; GO:0007568 aging; GO:0019222 regulation of metabolic process; GO:0071241 cellular response to inorganic substance; GO:0033143 regulation of intracellular steroid hormone receptor signaling pathway; GO:0072507 divalent inorganic cation homeostasis; GO:0051238 sequestering of metal ion; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0045807 positive regulation of endocytosis; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0030003 cellular cation homeostasis; GO:0031324 negative regulation of cellular metabolic process; GO:0034975 protein folding in endoplasmic reticulum; GO:0050896 response to stimulus; GO:0031958 corticosteroid receptor signaling pathway; GO:0055082 cellular chemical homeostasis; GO:2000510 positive regulation of dendritic cell chemotaxis; GO:0009987 cellular process; GO:0071156 regulation of cell cycle arrest; GO:0002397 MHC class I protein complex assembly; GO:0034620 cellular response to unfolded protein; GO:0022417 protein maturation by protein folding; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0006897 endocytosis; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0007276 gamete generation; GO:0051641 cellular localization; GO:0032504 multicellular organism reproduction; GO:0070727 cellular macromolecule localization; GO:0040020 regulation of meiotic nuclear division; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0006417 regulation of translation; GO:0022603 regulation of anatomical structure morphogenesis; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0006875 cellular metal ion homeostasis; GO:0051128 regulation of cellular component organization; GO:0009967 positive regulation of signal transduction; GO:0051604 protein maturation; GO:0040012 regulation of locomotion; GO:0009725 response to hormone; GO:0022604 regulation of cell morphogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0009897 external side of plasma membrane; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0033018 sarcoplasmic reticulum lumen; GO:0016528 sarcoplasm; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0098552 side of membrane; GO:0030666 endocytic vesicle membrane; GO:0070161 anchoring junction; GO:0012506 vesicle membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0031012 extracellular matrix; GO:0043231 intracellular membrane-bounded organelle; GO:0098553 lumenal side of endoplasmic reticulum membrane; GO:1990904 ribonucleoprotein complex; GO:0097223 sperm part; GO:0030529 intracellular ribonucleoprotein complex; GO:0043234 protein complex; GO:0030176 integral component of endoplasmic reticulum membrane; GO:0043230 extracellular organelle; GO:0005844 polysome; GO:0005790 smooth endoplasmic reticulum; GO:0005783 endoplasmic reticulum; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005615 extracellular space; GO:0031410 cytoplasmic vesicle; GO:0098796 membrane protein complex; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0044464 cell part; GO:0030670 phagocytic vesicle membrane; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0005912 adherens junction; GO:0048471 perinuclear region of cytoplasm; GO:0031227 intrinsic component of endoplasmic reticulum membrane; GO:0030141 secretory granule; GO:0030139 endocytic vesicle; GO:0042824 MHC class I peptide loading complex; GO:0005788 endoplasmic reticulum lumen; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane; GO:0044446 intracellular organelle part; GO:0016529 sarcoplasmic reticulum; GO:0045335 phagocytic vesicle; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0016021 integral component of membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0044459 plasma membrane part; GO:0044432 endoplasmic reticulum part; GO:0001669 acrosomal vesicle; GO:0005793 endoplasmic reticulum-Golgi intermediate compartment; GO:0005578 proteinaceous extracellular matrix; GO:0009986 cell surface; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; GO:0071682 endocytic vesicle lumen; ","GO:0031625 ubiquitin protein ligase binding; GO:0001846 opsonin binding; GO:0005102 receptor binding; GO:0042562 hormone binding; GO:0050681 androgen receptor binding; GO:0005515 protein binding; GO:0005178 integrin binding; GO:0051427 hormone receptor binding; GO:0044183 protein binding involved in protein folding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0003729 mRNA binding; GO:0042277 peptide binding; GO:0005488 binding; GO:0035258 steroid hormone receptor binding; GO:0043169 cation binding; GO:0003723 RNA binding; GO:0003677 DNA binding; GO:0005506 iron ion binding; GO:0001849 complement component C1q binding; GO:0051087 chaperone binding; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0033218 amide binding; GO:0008270 zinc ion binding; GO:0050839 cell adhesion molecule binding; GO:0097367 carbohydrate derivative binding; GO:0046914 transition metal ion binding; GO:0003676 nucleic acid binding; GO:0001848 complement binding; GO:0035257 nuclear hormone receptor binding; GO:0030246 carbohydrate binding; GO:0046872 metal ion binding; GO:0051082 unfolded protein binding; GO:0005509 calcium ion binding; GO:0001948 glycoprotein binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0019899 enzyme binding; GO:0032403 protein complex binding; ","K08057","CALR; calreticulin","hsa05142 Chagas disease (American trypanosomiasis) - Homo sapiens (human); hsa05166 HTLV-I infection - Homo sapiens (human); hsa04612 Antigen processing and presentation - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); ","IPR009033; IPR013320; ","\"Calreticulin/calnexin, P domain; Concanavalin A-like lectin/glucanase domain; \"\r"]
["P27816","Microtubule-associated protein 4 OS=Homo sapiens OX=9606 GN=MAP4","MAP4",121,189.66,27.4,28,52,28,1.014,1.013,1.047,0.975,0.969,0.993,0.955,0.0254,"nucleus\r","GO:0060491 regulation of cell projection assembly; GO:0007067 mitotic nuclear division; GO:0051129 negative regulation of cellular component organization; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:1902116 negative regulation of organelle assembly; GO:1902115 regulation of organelle assembly; GO:0051234 establishment of localization; GO:0051649 establishment of localization in cell; GO:1902855 regulation of non-motile cilium assembly; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0000278 mitotic cell cycle; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0051294 establishment of spindle orientation; GO:0007163 establishment or maintenance of cell polarity; GO:0032501 multicellular organismal process; GO:0010639 negative regulation of organelle organization; GO:0000226 microtubule cytoskeleton organization; GO:0050789 regulation of biological process; GO:0030030 cell projection organization; GO:1902850 microtubule cytoskeleton organization involved in mitosis; GO:0051301 cell division; GO:0048856 anatomical structure development; GO:0051640 organelle localization; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0048285 organelle fission; GO:0051653 spindle localization; GO:0007051 spindle organization; GO:0044087 regulation of cellular component biogenesis; GO:0031344 regulation of cell projection organization; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0048468 cell development; GO:0030154 cell differentiation; GO:0030010 establishment of cell polarity; GO:0031345 negative regulation of cell projection organization; GO:0007275 multicellular organism development; GO:0007052 mitotic spindle organization; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0051293 establishment of spindle localization; GO:0051012 microtubule sliding; GO:1902017 regulation of cilium assembly; GO:0048731 system development; GO:0033043 regulation of organelle organization; GO:0051656 establishment of organelle localization; GO:0031175 neuron projection development; GO:0007017 microtubule-based process; GO:0051641 cellular localization; GO:0007018 microtubule-based movement; GO:0030182 neuron differentiation; GO:1902856 negative regulation of non-motile cilium assembly; GO:1902018 negative regulation of cilium assembly; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0000280 nuclear division; GO:0006928 movement of cell or subcellular component; GO:0022402 cell cycle process; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0044421 extracellular region part; GO:0005874 microtubule; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0005623 cell; GO:0099080 supramolecular complex; GO:0032279 asymmetric synapse; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0072686 mitotic spindle; GO:0005856 cytoskeleton; GO:0044441 ciliary part; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0014069 postsynaptic density; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0098984 neuron to neuron synapse; GO:0005930 axoneme; GO:0044456 synapse part; GO:0005929 cilium; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0099513 polymeric cytoskeletal fiber; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0097014 ciliary plasm; GO:0044446 intracellular organelle part; GO:0005875 microtubule associated complex; GO:0044463 cell projection part; GO:0005819 spindle; GO:0005576 extracellular region; GO:0045202 synapse; GO:0099081 supramolecular polymer; GO:0043226 organelle; GO:0098794 postsynapse; GO:0099572 postsynaptic specialization; GO:0043234 protein complex; GO:0043230 extracellular organelle; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0008092 cytoskeletal protein binding; GO:0008017 microtubule binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0015631 tubulin binding; GO:0005515 protein binding; GO:0005198 structural molecule activity; ","K10431"]
["P28065","Proteasome subunit beta type-9 OS=Homo sapiens OX=9606 GN=PSMB9","PSMB9",23.264,8.2951,14.2,3,6,3,0.946,0.929,1.018,1.099,1.042,1.035,1.098,0.0501,"cyto_nucl\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0002220 innate immune response activating cell surface receptor signaling pathway; GO:0007166 cell surface receptor signaling pathway; GO:0010608 posttranscriptional regulation of gene expression; GO:0051443 positive regulation of ubiquitin-protein transferase activity; GO:0031347 regulation of defense response; GO:0071345 cellular response to cytokine stimulus; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:1903364 positive regulation of cellular protein catabolic process; GO:0008152 metabolic process; GO:0044093 positive regulation of molecular function; GO:0090263 positive regulation of canonical Wnt signaling pathway; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0051347 positive regulation of transferase activity; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0016055 Wnt signaling pathway; GO:0044419 interspecies interaction between organisms; GO:1903362 regulation of cellular protein catabolic process; GO:0052548 regulation of endopeptidase activity; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0006521 regulation of cellular amino acid metabolic process; GO:0002758 innate immune response-activating signal transduction; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0010972 negative regulation of G2/M transition of mitotic cell cycle; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0060828 regulation of canonical Wnt signaling pathway; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0033209 tumor necrosis factor-mediated signaling pathway; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0000165 MAPK cascade; GO:1903506 regulation of nucleic acid-templated transcription; GO:2000058 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0019884 antigen processing and presentation of exogenous antigen; GO:1901575 organic substance catabolic process; GO:0010948 negative regulation of cell cycle process; GO:0007267 cell-cell signaling; GO:0002223 stimulatory C-type lectin receptor signaling pathway; GO:0051336 regulation of hydrolase activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0030163 protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0060071 Wnt signaling pathway, planar cell polarity pathway; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:0002682 regulation of immune system process; GO:0006464 cellular protein modification process; GO:0031145 anaphase-promoting complex-dependent catabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016310 phosphorylation; GO:0033554 cellular response to stress; GO:0007346 regulation of mitotic cell cycle; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0051239 regulation of multicellular organismal process; GO:0043487 regulation of RNA stability; GO:0000209 protein polyubiquitination; GO:0031349 positive regulation of defense response; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0009889 regulation of biosynthetic process; GO:1901987 regulation of cell cycle phase transition; GO:0009896 positive regulation of catabolic process; GO:0043620 regulation of DNA-templated transcription in response to stress; GO:0070482 response to oxygen levels; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0044248 cellular catabolic process; GO:0010389 regulation of G2/M transition of mitotic cell cycle; GO:0042176 regulation of protein catabolic process; GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; GO:0038093 Fc receptor signaling pathway; GO:0050778 positive regulation of immune response; GO:0009966 regulation of signal transduction; GO:0023014 signal transduction by protein phosphorylation; GO:0071456 cellular response to hypoxia; GO:0038061 NIK/NF-kappaB signaling; GO:0002253 activation of immune response; GO:0006950 response to stress; GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; GO:0016567 protein ubiquitination; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress; GO:1904666 regulation of ubiquitin protein ligase activity; GO:1903321 negative regulation of protein modification by small protein conjugation or removal; GO:0055085 transmembrane transport; GO:0051247 positive regulation of protein metabolic process; GO:0051438 regulation of ubiquitin-protein transferase activity; GO:0031398 positive regulation of protein ubiquitination; GO:0032446 protein modification by small protein conjugation; GO:0006793 phosphorus metabolic process; GO:0030111 regulation of Wnt signaling pathway; GO:0031325 positive regulation of cellular metabolic process; GO:0030177 positive regulation of Wnt signaling pathway; GO:1904668 positive regulation of ubiquitin protein ligase activity; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0036293 response to decreased oxygen levels; GO:0051179 localization; GO:0043412 macromolecule modification; GO:0048584 positive regulation of response to stimulus; GO:0050793 regulation of developmental process; GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process; GO:0051444 negative regulation of ubiquitin-protein transferase activity; GO:0070646 protein modification by small protein removal; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0031331 positive regulation of cellular catabolic process; GO:0090090 negative regulation of canonical Wnt signaling pathway; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0031400 negative regulation of protein modification process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0035567 non-canonical Wnt signaling pathway; GO:0031396 regulation of protein ubiquitination; GO:1905330 regulation of morphogenesis of an epithelium; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0045930 negative regulation of mitotic cell cycle; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0045088 regulation of innate immune response; GO:1901991 negative regulation of mitotic cell cycle phase transition; GO:0009893 positive regulation of metabolic process; GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0034612 response to tumor necrosis factor; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0051726 regulation of cell cycle; GO:0070887 cellular response to chemical stimulus; GO:0050851 antigen receptor-mediated signaling pathway; GO:0010468 regulation of gene expression; GO:0030178 negative regulation of Wnt signaling pathway; GO:0034097 response to cytokine; GO:0031326 regulation of cellular biosynthetic process; GO:2000116 regulation of cysteine-type endopeptidase activity; GO:0048002 antigen processing and presentation of peptide antigen; GO:0048522 positive regulation of cellular process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0051348 negative regulation of transferase activity; GO:0070647 protein modification by small protein conjugation or removal; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0198738 cell-cell signaling by wnt; GO:0010565 regulation of cellular ketone metabolic process; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0036211 protein modification process; GO:0052547 regulation of peptidase activity; GO:2000026 regulation of multicellular organismal development; GO:0090175 regulation of establishment of planar polarity; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0045786 negative regulation of cell cycle; GO:1904667 negative regulation of ubiquitin protein ligase activity; GO:0002218 activation of innate immune response; GO:0044257 cellular protein catabolic process; GO:0071356 cellular response to tumor necrosis factor; GO:1901988 negative regulation of cell cycle phase transition; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0016579 protein deubiquitination; GO:0050896 response to stimulus; GO:0010498 proteasomal protein catabolic process; GO:0071704 organic substance metabolic process; GO:1903322 positive regulation of protein modification by small protein conjugation or removal; GO:0045862 positive regulation of proteolysis; GO:2000027 regulation of organ morphogenesis; GO:0006468 protein phosphorylation; GO:0023056 positive regulation of signaling; GO:0016032 viral process; GO:0001666 response to hypoxia; GO:0002757 immune response-activating signal transduction; GO:0006508 proteolysis; GO:0010647 positive regulation of cell communication; GO:0071453 cellular response to oxygen levels; GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:0019221 cytokine-mediated signaling pathway; GO:0009987 cellular process; GO:0033238 regulation of cellular amine metabolic process; GO:0031397 negative regulation of protein ubiquitination; GO:0043632 modification-dependent macromolecule catabolic process; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0045089 positive regulation of innate immune response; GO:0006355 regulation of transcription, DNA-templated; GO:0035556 intracellular signal transduction; GO:0019941 modification-dependent protein catabolic process; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0031401 positive regulation of protein modification process; GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia; GO:1902749 regulation of cell cycle G2/M phase transition; GO:0043488 regulation of mRNA stability; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0019882 antigen processing and presentation; GO:0050852 T cell receptor signaling pathway; GO:0051246 regulation of protein metabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0002684 positive regulation of immune system process; GO:0009057 macromolecule catabolic process; GO:0038095 Fc-epsilon receptor signaling pathway; GO:0051248 negative regulation of protein metabolic process; GO:0022402 cell cycle process; GO:0045732 positive regulation of protein catabolic process; GO:0009967 positive regulation of signal transduction; GO:1902750 negative regulation of cell cycle G2/M phase transition; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0036294 cellular response to decreased oxygen levels; GO:0065007 biological regulation; ","GO:0044421 extracellular region part; GO:1990111 spermatoproteasome complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:1905369 endopeptidase complex; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:1905368 peptidase complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0000502 proteasome complex; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005839 proteasome core complex; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0004175 endopeptidase activity; GO:0004298 threonine-type endopeptidase activity; GO:0008233 peptidase activity; GO:0070003 threonine-type peptidase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0016787 hydrolase activity; GO:0005515 protein binding; ","K02741","PSMB9; 20S proteasome subunit beta 9 [EC:3.4.25.1]","hsa03050 Proteasome - Homo sapiens (human); ","IPR029055; ","\"Nucleophile aminohydrolases, N-terminal; \"\r"]
["P28066","Proteasome subunit alpha type-5 OS=Homo sapiens OX=9606 GN=PSMA5","PSMA5",26.411,113.07,48.1,9,21,9,0.976,0.963,0.965,0.979,1.066,1.042,1.063,0.0789,"cytoplasm\r","GO:0044700 single organism signaling; GO:0010608 posttranscriptional regulation of gene expression; GO:0051443 positive regulation of ubiquitin-protein transferase activity; GO:0031347 regulation of defense response; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:1903364 positive regulation of cellular protein catabolic process; GO:0008152 metabolic process; GO:0044093 positive regulation of molecular function; GO:0090263 positive regulation of canonical Wnt signaling pathway; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0016055 Wnt signaling pathway; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0006521 regulation of cellular amino acid metabolic process; GO:0080090 regulation of primary metabolic process; GO:0010972 negative regulation of G2/M transition of mitotic cell cycle; GO:0044763 single-organism cellular process; GO:0060828 regulation of canonical Wnt signaling pathway; GO:0043086 negative regulation of catalytic activity; GO:0033209 tumor necrosis factor-mediated signaling pathway; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0000165 MAPK cascade; GO:0019884 antigen processing and presentation of exogenous antigen; GO:1901575 organic substance catabolic process; GO:0007267 cell-cell signaling; GO:0002223 stimulatory C-type lectin receptor signaling pathway; GO:0030163 protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0060071 Wnt signaling pathway, planar cell polarity pathway; GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0016310 phosphorylation; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0043487 regulation of RNA stability; GO:0000209 protein polyubiquitination; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0009889 regulation of biosynthetic process; GO:0009896 positive regulation of catabolic process; GO:0043620 regulation of DNA-templated transcription in response to stress; GO:0070482 response to oxygen levels; GO:0044248 cellular catabolic process; GO:0042176 regulation of protein catabolic process; GO:0038093 Fc receptor signaling pathway; GO:0050778 positive regulation of immune response; GO:0023014 signal transduction by protein phosphorylation; GO:0006950 response to stress; GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; GO:0016567 protein ubiquitination; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0002263 cell activation involved in immune response; GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress; GO:1903321 negative regulation of protein modification by small protein conjugation or removal; GO:0045055 regulated exocytosis; GO:0031398 positive regulation of protein ubiquitination; GO:0032446 protein modification by small protein conjugation; GO:0031325 positive regulation of cellular metabolic process; GO:0030177 positive regulation of Wnt signaling pathway; GO:1904668 positive regulation of ubiquitin protein ligase activity; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0006955 immune response; GO:0043412 macromolecule modification; GO:0070646 protein modification by small protein removal; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0031331 positive regulation of cellular catabolic process; GO:0044699 single-organism process; GO:0031400 negative regulation of protein modification process; GO:0006796 phosphate-containing compound metabolic process; GO:0031396 regulation of protein ubiquitination; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0045930 negative regulation of mitotic cell cycle; GO:0009893 positive regulation of metabolic process; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0034612 response to tumor necrosis factor; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0051726 regulation of cell cycle; GO:0034097 response to cytokine; GO:0031326 regulation of cellular biosynthetic process; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0198738 cell-cell signaling by wnt; GO:0010565 regulation of cellular ketone metabolic process; GO:0032940 secretion by cell; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0036211 protein modification process; GO:0090175 regulation of establishment of planar polarity; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0045786 negative regulation of cell cycle; GO:0044257 cellular protein catabolic process; GO:1901988 negative regulation of cell cycle phase transition; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0010498 proteasomal protein catabolic process; GO:0071704 organic substance metabolic process; GO:0045862 positive regulation of proteolysis; GO:2000027 regulation of organ morphogenesis; GO:0006468 protein phosphorylation; GO:0023056 positive regulation of signaling; GO:0001666 response to hypoxia; GO:0002757 immune response-activating signal transduction; GO:0010647 positive regulation of cell communication; GO:0071453 cellular response to oxygen levels; GO:0019221 cytokine-mediated signaling pathway; GO:0031397 negative regulation of protein ubiquitination; GO:0006355 regulation of transcription, DNA-templated; GO:0035556 intracellular signal transduction; GO:0019941 modification-dependent protein catabolic process; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia; GO:1902749 regulation of cell cycle G2/M phase transition; GO:0043488 regulation of mRNA stability; GO:0043085 positive regulation of catalytic activity; GO:0002366 leukocyte activation involved in immune response; GO:0019882 antigen processing and presentation; GO:0042119 neutrophil activation; GO:0050852 T cell receptor signaling pathway; GO:0002684 positive regulation of immune system process; GO:0038095 Fc-epsilon receptor signaling pathway; GO:0051248 negative regulation of protein metabolic process; GO:0022402 cell cycle process; GO:1902750 negative regulation of cell cycle G2/M phase transition; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0045321 leukocyte activation; GO:0002220 innate immune response activating cell surface receptor signaling pathway; GO:0007166 cell surface receptor signaling pathway; GO:0071345 cellular response to cytokine stimulus; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0051347 positive regulation of transferase activity; GO:1903362 regulation of cellular protein catabolic process; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0002443 leukocyte mediated immunity; GO:0002758 innate immune response-activating signal transduction; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0031323 regulation of cellular metabolic process; GO:2000058 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0010948 negative regulation of cell cycle process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0002682 regulation of immune system process; GO:0031145 anaphase-promoting complex-dependent catabolic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0007346 regulation of mitotic cell cycle; GO:0002283 neutrophil activation involved in immune response; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:0051239 regulation of multicellular organismal process; GO:0031349 positive regulation of defense response; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:1901987 regulation of cell cycle phase transition; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0010389 regulation of G2/M transition of mitotic cell cycle; GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; GO:0009966 regulation of signal transduction; GO:0038061 NIK/NF-kappaB signaling; GO:0071456 cellular response to hypoxia; GO:0002253 activation of immune response; GO:0016192 vesicle-mediated transport; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1904666 regulation of ubiquitin protein ligase activity; GO:0055085 transmembrane transport; GO:0051247 positive regulation of protein metabolic process; GO:0051438 regulation of ubiquitin-protein transferase activity; GO:0030111 regulation of Wnt signaling pathway; GO:0006793 phosphorus metabolic process; GO:0001775 cell activation; GO:0036293 response to decreased oxygen levels; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process; GO:0006887 exocytosis; GO:0051444 negative regulation of ubiquitin-protein transferase activity; GO:0090090 negative regulation of canonical Wnt signaling pathway; GO:0051234 establishment of localization; GO:0035567 non-canonical Wnt signaling pathway; GO:1905330 regulation of morphogenesis of an epithelium; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:1901991 negative regulation of mitotic cell cycle phase transition; GO:0045088 regulation of innate immune response; GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I; GO:0070887 cellular response to chemical stimulus; GO:0002274 myeloid leukocyte activation; GO:0050851 antigen receptor-mediated signaling pathway; GO:0010468 regulation of gene expression; GO:0030178 negative regulation of Wnt signaling pathway; GO:0048002 antigen processing and presentation of peptide antigen; GO:0002446 neutrophil mediated immunity; GO:0048522 positive regulation of cellular process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0051348 negative regulation of transferase activity; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0019222 regulation of metabolic process; GO:0043299 leukocyte degranulation; GO:2000026 regulation of multicellular organismal development; GO:0002218 activation of innate immune response; GO:1904667 negative regulation of ubiquitin protein ligase activity; GO:0002252 immune effector process; GO:0071356 cellular response to tumor necrosis factor; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0016579 protein deubiquitination; GO:1903322 positive regulation of protein modification by small protein conjugation or removal; GO:0006508 proteolysis; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:0033238 regulation of cellular amine metabolic process; GO:0043632 modification-dependent macromolecule catabolic process; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0045089 positive regulation of innate immune response; GO:0031401 positive regulation of protein modification process; GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0051246 regulation of protein metabolic process; GO:0009057 macromolecule catabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0009967 positive regulation of signal transduction; GO:0045732 positive regulation of protein catabolic process; GO:0036294 cellular response to decreased oxygen levels; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:1905369 endopeptidase complex; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:1905368 peptidase complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0019773 proteasome core complex, alpha-subunit complex; GO:0000502 proteasome complex; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0005839 proteasome core complex; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0004175 endopeptidase activity; GO:0004298 threonine-type endopeptidase activity; GO:0008233 peptidase activity; GO:0070003 threonine-type peptidase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0016787 hydrolase activity; GO:0005515 protein binding; ","K02729","PSMA5; 20S proteasome subunit alpha 5 [EC:3.4.25.1]","hsa03050 Proteasome - Homo sapiens (human); ","IPR029055; IPR000426; ","\"Nucleophile aminohydrolases, N-terminal; Proteasome alpha-subunit, N-terminal domain; \"\r"]
["P28161","Glutathione S-transferase Mu 2 OS=Homo sapiens OX=9606 GN=GSTM2","GSTM2",25.744,46.421,51.4,13,18,6,1.034,1.056,1.101,0.886,0.983,0.952,0.884,0.0259,"cytoplasm\r","GO:0044700 single organism signaling; GO:0050850 positive regulation of calcium-mediated signaling; GO:2000273 positive regulation of receptor activity; GO:0065008 regulation of biological quality; GO:0006518 peptide metabolic process; GO:0051410 detoxification of nitrogen compound; GO:0044255 cellular lipid metabolic process; GO:1903170 negative regulation of calcium ion transmembrane transport; GO:1904427 positive regulation of calcium ion transmembrane transport; GO:0044237 cellular metabolic process; GO:0044272 sulfur compound biosynthetic process; GO:0010469 regulation of receptor activity; GO:0090281 negative regulation of calcium ion import; GO:1901685 glutathione derivative metabolic process; GO:0008152 metabolic process; GO:1901019 regulation of calcium ion transmembrane transporter activity; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0044057 regulation of system process; GO:0032414 positive regulation of ion transmembrane transporter activity; GO:0009719 response to endogenous stimulus; GO:0032787 monocarboxylic acid metabolic process; GO:0098869 cellular oxidant detoxification; GO:1901020 negative regulation of calcium ion transmembrane transporter activity; GO:0051051 negative regulation of transport; GO:0006790 sulfur compound metabolic process; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0044281 small molecule metabolic process; GO:0043651 linoleic acid metabolic process; GO:0043269 regulation of ion transport; GO:0044763 single-organism cellular process; GO:0019932 second-messenger-mediated signaling; GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; GO:0032501 multicellular organismal process; GO:0034762 regulation of transmembrane transport; GO:0010243 response to organonitrogen compound; GO:1902532 negative regulation of intracellular signal transduction; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:2001257 regulation of cation channel activity; GO:1901698 response to nitrogen compound; GO:1901021 positive regulation of calcium ion transmembrane transporter activity; GO:0032412 regulation of ion transmembrane transporter activity; GO:0071312 cellular response to alkaloid; GO:0043436 oxoacid metabolic process; GO:0033559 unsaturated fatty acid metabolic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0034764 positive regulation of transmembrane transport; GO:0043279 response to alkaloid; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0032844 regulation of homeostatic process; GO:0051239 regulation of multicellular organismal process; GO:0060341 regulation of cellular localization; GO:0023057 negative regulation of signaling; GO:1990748 cellular detoxification; GO:0010648 negative regulation of cell communication; GO:0009410 response to xenobiotic stimulus; GO:0019722 calcium-mediated signaling; GO:0014074 response to purine-containing compound; GO:0044248 cellular catabolic process; GO:0010959 regulation of metal ion transport; GO:0050848 regulation of calcium-mediated signaling; GO:0009966 regulation of signal transduction; GO:0032409 regulation of transporter activity; GO:1904062 regulation of cation transmembrane transport; GO:0051928 positive regulation of calcium ion transport; GO:0034763 negative regulation of transmembrane transport; GO:0042537 benzene-containing compound metabolic process; GO:1902531 regulation of intracellular signal transduction; GO:0051282 regulation of sequestering of calcium ion; GO:0044711 single-organism biosynthetic process; GO:0006950 response to stress; GO:0051926 negative regulation of calcium ion transport; GO:0010523 negative regulation of calcium ion transport into cytosol; GO:0051924 regulation of calcium ion transport; GO:0071407 cellular response to organic cyclic compound; GO:2000272 negative regulation of receptor activity; GO:0071415 cellular response to purine-containing compound; GO:0010033 response to organic substance; GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:2001259 positive regulation of cation channel activity; GO:0034766 negative regulation of ion transmembrane transport; GO:0050849 negative regulation of calcium-mediated signaling; GO:0042178 xenobiotic catabolic process; GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling; GO:0043270 positive regulation of ion transport; GO:1904064 positive regulation of cation transmembrane transport; GO:0001676 long-chain fatty acid metabolic process; GO:0051280 negative regulation of release of sequestered calcium ion into cytosol; GO:0048584 positive regulation of response to stimulus; GO:1901564 organonitrogen compound metabolic process; GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling; GO:0003012 muscle system process; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity; GO:0055119 relaxation of cardiac muscle; GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0055117 regulation of cardiac muscle contraction; GO:0032846 positive regulation of homeostatic process; GO:0014819 regulation of skeletal muscle contraction; GO:0006749 glutathione metabolic process; GO:2001258 negative regulation of cation channel activity; GO:0032413 negative regulation of ion transmembrane transporter activity; GO:0070887 cellular response to chemical stimulus; GO:0006629 lipid metabolic process; GO:0051284 positive regulation of sequestering of calcium ion; GO:0051279 regulation of release of sequestered calcium ion into cytosol; GO:0070458 cellular detoxification of nitrogen compound; GO:0009636 response to toxic substance; GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; GO:1901360 organic cyclic compound metabolic process; GO:0090280 positive regulation of calcium ion import; GO:0048522 positive regulation of cellular process; GO:0022898 regulation of transmembrane transporter activity; GO:0043603 cellular amide metabolic process; GO:0071313 cellular response to caffeine; GO:0090257 regulation of muscle system process; GO:0023052 signaling; GO:0006942 regulation of striated muscle contraction; GO:0051050 positive regulation of transport; GO:0071417 cellular response to organonitrogen compound; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:1901699 cellular response to nitrogen compound; GO:0034767 positive regulation of ion transmembrane transport; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0006082 organic acid metabolic process; GO:0098754 detoxification; GO:0071466 cellular response to xenobiotic stimulus; GO:0006725 cellular aromatic compound metabolic process; GO:2000021 regulation of ion homeostasis; GO:0032411 positive regulation of transporter activity; GO:0071310 cellular response to organic substance; GO:1903522 regulation of blood circulation; GO:0031000 response to caffeine; GO:0008016 regulation of heart contraction; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0090075 relaxation of muscle; GO:0006575 cellular modified amino acid metabolic process; GO:0006805 xenobiotic metabolic process; GO:0023056 positive regulation of signaling; GO:0032410 negative regulation of transporter activity; GO:1903169 regulation of calcium ion transmembrane transport; GO:0034641 cellular nitrogen compound metabolic process; GO:0010647 positive regulation of cell communication; GO:0010524 positive regulation of calcium ion transport into cytosol; GO:0009987 cellular process; GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity; GO:0043271 negative regulation of ion transport; GO:0003008 system process; GO:0035556 intracellular signal transduction; GO:0051049 regulation of transport; GO:0090279 regulation of calcium ion import; GO:0006937 regulation of muscle contraction; GO:0006807 nitrogen compound metabolic process; GO:0048585 negative regulation of response to stimulus; GO:0032845 negative regulation of homeostatic process; GO:0006631 fatty acid metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:1901687 glutathione derivative biosynthetic process; GO:1904063 negative regulation of cation transmembrane transport; GO:0034765 regulation of ion transmembrane transport; GO:0051281 positive regulation of release of sequestered calcium ion into cytosol; GO:0071495 cellular response to endogenous stimulus; GO:0010522 regulation of calcium ion transport into cytosol; GO:0019752 carboxylic acid metabolic process; GO:0009967 positive regulation of signal transduction; GO:0009056 catabolic process; GO:0018916 nitrobenzene metabolic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0016529 sarcoplasmic reticulum; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0016528 sarcoplasm; GO:0005623 cell; GO:0005576 extracellular region; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0004602 glutathione peroxidase activity; GO:0005102 receptor binding; GO:0046983 protein dimerization activity; GO:0043167 ion binding; GO:0016209 antioxidant activity; GO:0005515 protein binding; GO:0033218 amide binding; GO:0043295 glutathione binding; GO:1900750 oligopeptide binding; GO:1901681 sulfur compound binding; GO:0016491 oxidoreductase activity; GO:0004364 glutathione transferase activity; GO:0042802 identical protein binding; GO:0072341 modified amino acid binding; GO:0003824 catalytic activity; GO:0042277 peptide binding; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups; GO:0043168 anion binding; GO:0004601 peroxidase activity; GO:0016740 transferase activity; GO:0019899 enzyme binding; GO:0016684 oxidoreductase activity, acting on peroxide as acceptor; ","K00799","GST; glutathione S-transferase [EC:2.5.1.18]","hsa01524 Platinum drug resistance - Homo sapiens (human); hsa00480 Glutathione metabolism - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa05204 Chemical carcinogenesis - Homo sapiens (human); hsa00980 Metabolism of xenobiotics by cytochrome P450 - Homo sapiens (human); hsa05225 Hepatocellular carcinoma - Homo sapiens (human); hsa00983 Drug metabolism - other enzymes - Homo sapiens (human); hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human); hsa00982 Drug metabolism - cytochrome P450 - Homo sapiens (human); hsa05215 Prostate cancer - Homo sapiens (human); ","IPR004046; IPR010987; IPR012336; IPR004045; ","\"Glutathione S-transferase, C-terminal; Glutathione S-transferase, C-terminal-like; Thioredoxin-like fold; Glutathione S-transferase, N-terminal; \"\r"]
["P28288","ATP-binding cassette sub-family D member 3 OS=Homo sapiens OX=9606 GN=ABCD3","ABCD3",75.475,9.6146,7.3,5,7,5,0.988,1.015,1.013,0.965,0.97,1.056,0.992,0.78,"mitochondria\r","GO:0016053 organic acid biosynthetic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0008610 lipid biosynthetic process; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0015718 monocarboxylic acid transport; GO:0030258 lipid modification; GO:0032787 monocarboxylic acid metabolic process; GO:0033036 macromolecule localization; GO:0006629 lipid metabolic process; GO:0044765 single-organism transport; GO:0019395 fatty acid oxidation; GO:0014070 response to organic cyclic compound; GO:0006869 lipid transport; GO:0015910 peroxisomal long-chain fatty acid import; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0072329 monocarboxylic acid catabolic process; GO:0046942 carboxylic acid transport; GO:0006633 fatty acid biosynthetic process; GO:0046395 carboxylic acid catabolic process; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0046394 carboxylic acid biosynthetic process; GO:0042221 response to chemical; GO:0044710 single-organism metabolic process; GO:0006082 organic acid metabolic process; GO:0009062 fatty acid catabolic process; GO:0043436 oxoacid metabolic process; GO:0016043 cellular component organization; GO:0034440 lipid oxidation; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0007031 peroxisome organization; GO:0042493 response to drug; GO:0015908 fatty acid transport; GO:1902578 single-organism localization; GO:0044248 cellular catabolic process; GO:0042760 very long-chain fatty acid catabolic process; GO:0009987 cellular process; GO:0016042 lipid catabolic process; GO:0044711 single-organism biosynthetic process; GO:0044712 single-organism catabolic process; GO:0006635 fatty acid beta-oxidation; GO:0071702 organic substance transport; GO:0010876 lipid localization; GO:0044282 small molecule catabolic process; GO:0010033 response to organic substance; GO:0006631 fatty acid metabolic process; GO:0044238 primary metabolic process; GO:0015849 organic acid transport; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0015909 long-chain fatty acid transport; GO:0006820 anion transport; GO:0000038 very long-chain fatty acid metabolic process; GO:0055085 transmembrane transport; GO:0015711 organic anion transport; GO:0006996 organelle organization; GO:0006811 ion transport; GO:0019752 carboxylic acid metabolic process; GO:0016054 organic acid catabolic process; GO:0044283 small molecule biosynthetic process; GO:0044242 cellular lipid catabolic process; GO:0051179 localization; GO:0072330 monocarboxylic acid biosynthetic process; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044438 microbody part; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005778 peroxisomal membrane; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0005782 peroxisomal matrix; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0042579 microbody; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0031903 microbody membrane; GO:0044429 mitochondrial part; GO:0044439 peroxisomal part; GO:0098588 bounding membrane of organelle; GO:0005777 peroxisome; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005829 cytosol; GO:0016021 integral component of membrane; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031907 microbody lumen; GO:0031975 envelope; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0043621 protein self-association; GO:0015399 primary active transmembrane transporter activity; GO:0046983 protein dimerization activity; GO:0005319 lipid transporter activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0022892 substrate-specific transporter activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0016887 ATPase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0042802 identical protein binding; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0043492 ATPase activity, coupled to movement of substances; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0015245 fatty acid transporter activity; GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005215 transporter activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0022804 active transmembrane transporter activity; GO:0005524 ATP binding; GO:0005324 long-chain fatty acid transporter activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity; GO:0097367 carbohydrate derivative binding; GO:0042626 ATPase activity, coupled to transmembrane movement of substances; GO:0042803 protein homodimerization activity; GO:0042623 ATPase activity, coupled; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0022857 transmembrane transporter activity; GO:0036094 small molecule binding; ","K05677","ABCD3; ATP-binding cassette, subfamily D (ALD), member 3","hsa02010 ABC transporters - Homo sapiens (human); hsa04146 Peroxisome - Homo sapiens (human); ","IPR003593; IPR003439; IPR027417; IPR011527; ","\"AAA+ ATPase domain; ABC transporter-like; P-loop containing nucleoside triphosphate hydrolase; ABC transporter type 1, transmembrane domain; \"\r"]
["P28331","NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS1","NDUFS1",79.467,87.841,29.3,18,25,18,0.965,1.056,1.039,0.971,0.982,0.973,0.956,0.256,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0006753 nucleoside phosphate metabolic process; GO:0007005 mitochondrion organization; GO:0006915 apoptotic process; GO:0019693 ribose phosphate metabolic process; GO:0071822 protein complex subunit organization; GO:0010257 NADH dehydrogenase complex assembly; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0006119 oxidative phosphorylation; GO:0044763 single-organism cellular process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0006120 mitochondrial electron transport, NADH to ubiquinone; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0042391 regulation of membrane potential; GO:0097031 mitochondrial respiratory chain complex I biogenesis; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0022900 electron transport chain; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0070271 protein complex biogenesis; GO:0033108 mitochondrial respiratory chain complex assembly; GO:0016043 cellular component organization; GO:0016310 phosphorylation; GO:0006725 cellular aromatic compound metabolic process; GO:0042773 ATP synthesis coupled electron transport; GO:0009259 ribonucleotide metabolic process; GO:0022904 respiratory electron transport chain; GO:0071704 organic substance metabolic process; GO:0032981 mitochondrial respiratory chain complex I assembly; GO:0046483 heterocycle metabolic process; GO:0072593 reactive oxygen species metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009119 ribonucleoside metabolic process; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0043623 cellular protein complex assembly; GO:0046034 ATP metabolic process; GO:0034622 cellular macromolecular complex assembly; GO:0008637 apoptotic mitochondrial changes; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0045333 cellular respiration; GO:0006163 purine nucleotide metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0046128 purine ribonucleoside metabolic process; GO:0006793 phosphorus metabolic process; GO:0008219 cell death; GO:0006996 organelle organization; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0012501 programmed cell death; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:0051881 regulation of mitochondrial membrane potential; GO:0065007 biological regulation; GO:1901564 organonitrogen compound metabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0045271 respiratory chain complex I; GO:0032991 macromolecular complex; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0005747 mitochondrial respiratory chain complex I; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0031970 organelle envelope lumen; GO:0070013 intracellular organelle lumen; GO:0043209 myelin sheath; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0098803 respiratory chain complex; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005759 mitochondrial matrix; GO:0044429 mitochondrial part; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0005739 mitochondrion; GO:0005746 mitochondrial respiratory chain; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0030964 NADH dehydrogenase complex; GO:0005758 mitochondrial intermembrane space; GO:0031975 envelope; GO:1990204 oxidoreductase complex; GO:0043234 protein complex; GO:0031966 mitochondrial membrane; GO:0070469 respiratory chain; GO:0044444 cytoplasmic part; ","GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:0051537 2 iron, 2 sulfur cluster binding; GO:0043167 ion binding; GO:0050136 NADH dehydrogenase (quinone) activity; GO:0005515 protein binding; GO:0051539 4 iron, 4 sulfur cluster binding; GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; GO:0008137 NADH dehydrogenase (ubiquinone) activity; GO:0016491 oxidoreductase activity; GO:0009055 electron carrier activity; GO:0003954 NADH dehydrogenase activity; GO:0003824 catalytic activity; GO:0051536 iron-sulfur cluster binding; GO:0005488 binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0051540 metal cluster binding; ","K03934","NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:1.6.5.3 1.6.99.3]","hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); ","IPR019574; IPR006656; IPR001041; IPR012675; IPR006963; IPR015405; ","\"NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; Molybdopterin oxidoreductase; 2Fe-2S ferredoxin-type iron-sulfur binding domain; Beta-grasp domain; Molybdopterin oxidoreductase, 4Fe-4S domain; NADH-quinone oxidoreductase, chain G, C-terminal; \"\r"]
["P28482","Mitogen-activated protein kinase 1 OS=Homo sapiens OX=9606 GN=MAPK1","MAPK1",41.389,49.49,26.4,11,21,10,0.971,0.958,0.979,0.968,1.039,1.032,1.045,0.136,"cytoplasm\r",{"$cut":{"chars":21914,"head":"GO:0044700 single organism signaling; GO:0035094 response to nicotine; GO:0032872 regulation of stress-activated MAPK cascade; GO:0048732 gland development; GO:0022414 reproductive process; GO:0061308 cardiac neural crest cell development involved in heart development; GO:0043009 chordate embryonic development; GO:0030323 respiratory tube development; GO:0010608 posttranscriptional regulation of gene expression; GO:0001892 embryonic placenta development; GO:0030878 thyroid gland development; GO:0009891 positive regulation of biosynthetic process; GO:0044237 cellular metabolic process; GO:0060674 placenta blood vessel development; GO:0009607 response to biotic stimulus; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0008152 metabolic process; GO:0044093 positive regulation of molecular function; GO:0072527 pyrimidine-containing compound metabolic process; GO:0051493 regulation of cytoskeleton organization; GO:0009790 embryo development; GO:0006606 protein import into nucleus; GO:0048598 embryonic morphogenesis; GO:0090596 sensory organ morphogenesis; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0030168 platelet activation; GO:0051054 positive regulation of DNA metabolic process; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0002520 immune system development; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0006935 chemotaxis; GO:0071396 cellular response to lipid; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0050673 epithelial cell proliferation; GO:0006810 transport; GO:0000165 MAPK cascade; GO:0010243 response to organonitrogen compound; GO:0042063 gliogenesis; GO:0007267 cell-cell signaling; GO:0080135 regulation of cellular response to stress; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:1901698 response to nitrogen compound; GO:0009112 nucleobase metabolic process; GO:0006913 nucleocytoplasmic transport; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0000003 reproduction; GO:0072359 circulatory system development; GO:0016310 phosphorylation; GO:0044707 single-multicellular organism process; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:1901700 response to oxygen-containing compound; GO:0048519 negative regulation of biological process; GO:0009653 anatomical structure morphogenesis; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0060541 respiratory system development; GO:0009889 regulation of biosynthetic process; GO:2000145 regulation of cell motility; GO:2000641 regulation of early endosome to late endosome transport; GO:0044744 protein targeting to nucleus; GO:1902680 positive regulation of RNA biosynthetic process; GO:1902580 single-organism cellular localization; GO:0038093 Fc receptor signaling pathway; GO:0061458 reproductive system development; GO:0034613 cellular protein localization; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0050778 positive regulation of immune response; GO:0023014 signal transduction by protein phosphorylation; GO:0006950 response to stress; GO:0032496 response to lipopolysaccharide; GO:0051270 regulation of cellular component movement; GO:0060440 trachea formation; GO:0050804 modulation of synaptic transmission; GO:0002376 immune system process; GO:0008283 cell proliferation; GO:0010033 response to organic substance; GO:0002263 cell activation involved in immune response; GO:1901576 organic substance biosynthetic process; GO:2000278 regulation of DNA biosynthetic process; GO:0006974 cellular response to DNA damage stimulus; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0034248 regulation of cellular amide metabolic process; GO:0045055 regulated exocytosis; GO:0099536 synaptic signali"}},"GO:0016020 membrane; GO:0030425 dendrite; GO:0044421 extracellular region part; GO:0098857 membrane microdomain; GO:0099568 cytoplasmic region; GO:0005737 cytoplasm; GO:0043025 neuronal cell body; GO:0032838 cell projection cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0031143 pseudopodium; GO:0044422 organelle part; GO:0005769 early endosome; GO:0043228 non-membrane-bounded organelle; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0005654 nucleoplasm; GO:0032839 dendrite cytoplasm; GO:0098590 plasma membrane region; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:0098589 membrane region; GO:0043005 neuron projection; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0042995 cell projection; GO:0005770 late endosome; GO:0044430 cytoskeletal part; GO:0070161 anchoring junction; GO:0031981 nuclear lumen; GO:0005901 caveola; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0042582 azurophil granule; GO:0030424 axon; GO:0043231 intracellular membrane-bounded organelle; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0043204 perikaryon; GO:0005773 vacuole; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0034774 secretory granule lumen; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005856 cytoskeleton; GO:0072686 mitotic spindle; GO:0031974 membrane-enclosed lumen; GO:0005815 microtubule organizing center; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0044425 membrane part; GO:0044464 cell part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0005912 adherens junction; GO:0005768 endosome; GO:0030141 secretory granule; GO:0045121 membrane raft; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0005819 spindle; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0060205 cytoplasmic vesicle lumen; GO:0044853 plasma membrane raft; GO:0044297 cell body; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0019901 protein kinase binding; GO:0005515 protein binding; GO:0004672 protein kinase activity; GO:0004702 signal transducer, downstream of receptor, with serine/threonine kinase activity; GO:0004871 signal transducer activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016301 kinase activity; GO:0042802 identical protein binding; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0001784 phosphotyrosine binding; GO:0019902 phosphatase binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003677 DNA binding; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity; GO:0045309 protein phosphorylated amino acid binding; GO:0000166 nucleotide binding; GO:0019900 kinase binding; GO:0004707 MAP kinase activity; GO:0051219 phosphoprotein binding; GO:0032549 ribonucleoside binding; GO:0005057 signal transducer activity, downstream of receptor; GO:0097367 carbohydrate derivative binding; GO:0031435 mitogen-activated protein kinase kinase kinase binding; GO:0003676 nucleic acid binding; GO:0004674 protein serine/threonine kinase activity; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0008134 transcription factor binding; GO:0019899 enzyme binding; GO:0036094 small molecule binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K04371","MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]","hsa05152 Tuberculosis - Homo sapiens (human); hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human); hsa04662 B cell receptor signaling pathway - Homo sapiens (human); hsa05220 Chronic myeloid leukemia - Homo sapiens (human); hsa04014 Ras signaling pathway - Homo sapiens (human); hsa04150 mTOR signaling pathway - Homo sapiens (human); hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa05206 MicroRNAs in cancer - Homo sapiens (human); hsa05145 Toxoplasmosis - Homo sapiens (human); hsa05164 Influenza A - Homo sapiens (human); hsa04960 Aldosterone-regulated sodium reabsorption - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa04934 Cushing's syndrome - Homo sapiens (human); hsa04933 AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human); hsa04659 Th17 cell differentiation - Homo sapiens (human); hsa04611 Platelet activation - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa04917 Prolactin signaling pathway - Homo sapiens (human); hsa05161 Hepatitis B - Homo sapiens (human); hsa04930 Type II diabetes mellitus - Homo sapiens (human); hsa05215 Prostate cancer - Homo sapiens (human); hsa01521 EGFR tyrosine kinase inhibitor resistance - Homo sapiens (human); hsa04914 Progesterone-mediated oocyte maturation - Homo sapiens (human); hsa04725 Cholinergic synapse - Homo sapiens (human); hsa05142 Chagas disease (American trypanosomiasis) - Homo sapiens (human); hsa04921 Oxytocin signaling pathway - Homo sapiens (human); hsa04218 Cellular senescence - Homo sapiens (human); hsa04722 Neurotrophin signaling pathway - Homo sapiens (human); hsa04371 Apelin signaling pathway - Homo sapiens (human); hsa05160 Hepatitis C - Homo sapiens (human); hsa04916 Melanogenesis - Homo sapiens (human); hsa04270 Vascular smooth muscle contraction - Homo sapiens (human); hsa05167 Kaposi's sarcoma-associated herpesvirus infection - Homo sapiens (human); hsa04350 TGF-beta signaling pathway - Homo sapiens (human); hsa04010 MAPK signaling pathway - Homo sapiens (human); hsa01524 Platinum drug resistance - Homo sapiens (human); hsa05219 Bladder cancer - Homo sapiens (human); hsa04664 Fc epsilon RI signaling pathway - Homo sapiens (human); hsa04657 IL-17 signaling pathway - Homo sapiens (human); hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human); hsa04540 Gap junction - Homo sapiens (human); hsa04912 GnRH signaling pathway - Homo sapiens (human); hsa04668 TNF signaling pathway - Homo sapiens (human); hsa05020 Prion diseases - Homo sapiens (human); hsa05203 Viral carcinogenesis - Homo sapiens (human); hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human); hsa04730 Long-term depression - Homo sapiens (human); hsa05133 Pertussis - Homo sapiens (human); hsa05226 Gastric cancer - Homo sapiens (human); hsa04720 Long-term potentiation - Homo sapiens (human); hsa04713 Circadian entrainment - Homo sapiens (human); hsa04928 Parathyroid hormone synthesis, secretion and action - Homo sapiens (human); hsa05218 Melanoma - Homo sapiens (human); hsa05212 Pancreatic cancer - Homo sapiens (human); hsa04550 Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human); hsa04015 Rap1 signaling pathway - Homo sapiens (human); hsa04072 Phospholipase D signaling pathway - Homo sapiens (human); hsa04650 Natural killer cell mediated cytotoxicity - Homo sapiens (human); hsa05221 Acute myeloid leukemia - Homo sapiens (human); hsa04625 C-type lectin receptor signaling pathway - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa05230 Central carbon metabolism in cancer - Homo sapiens (human); hsa04724 Glutamatergic synapse - Homo sapiens (human); hsa05131 Shigellosis - Homo sapiens (human); hsa04140 Autophagy - animal - Homo sapiens (human); hsa04114 Oocyte meiosis - Homo sapiens (human); hsa04380 Osteoclast differentiation - Homo sapiens (human); hsa04071 Sphingolipid signaling pathway - Homo sapiens (human); hsa05213 Endometrial cancer - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa05224 Breast cancer - Homo sapiens (human); hsa04520 Adherens junction - Homo sapiens (human); hsa01522 Endocrine resistance - Homo sapiens (human); hsa05034 Alcoholism - Homo sapiens (human); hsa05210 Colorectal cancer - Homo sapiens (human); hsa04915 Estrogen signaling pathway - Homo sapiens (human); hsa05010 Alzheimer's disease - Homo sapiens (human); hsa05216 Thyroid cancer - Homo sapiens (human); hsa05132 Salmonella infection - Homo sapiens (human); hsa05231 Choline metabolism in cancer - Homo sapiens (human); hsa04620 Toll-like receptor signaling pathway - Homo sapiens (human); hsa04210 Apoptosis - Homo sapiens (human); hsa04370 VEGF signaling pathway - Homo sapiens (human); hsa05140 Leishmaniasis - Homo sapiens (human); hsa04910 Insulin signaling pathway - Homo sapiens (human); hsa05211 Renal cell carcinoma - Homo sapiens (human); hsa05225 Hepatocellular carcinoma - Homo sapiens (human); hsa04024 cAMP signaling pathway - Homo sapiens (human); hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa04660 T cell receptor signaling pathway - Homo sapiens (human); hsa04726 Serotonergic synapse - Homo sapiens (human); hsa04658 Th1 and Th2 cell differentiation - Homo sapiens (human); hsa04062 Chemokine signaling pathway - Homo sapiens (human); hsa05223 Non-small cell lung cancer - Homo sapiens (human); hsa04666 Fc gamma R-mediated phagocytosis - Homo sapiens (human); hsa04066 HIF-1 signaling pathway - Homo sapiens (human); hsa05214 Glioma - Homo sapiens (human); hsa04068 FoxO signaling pathway - Homo sapiens (human); hsa04012 ErbB signaling pathway - Homo sapiens (human); hsa04360 Axon guidance - Homo sapiens (human); hsa04926 Relaxin signaling pathway - Homo sapiens (human); ","IPR000719; IPR011009; ","Protein kinase domain; Protein kinase-like domain; \r"]
["P28838","Cytosol aminopeptidase OS=Homo sapiens OX=9606 GN=LAP3","LAP3",56.166,197.63,57.4,24,48,24,0.933,0.924,0.93,1.069,1.067,1.072,1.151,7.58e-07,"mitochondria\r","GO:0006508 proteolysis; GO:0008152 metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0044238 primary metabolic process; GO:0071704 organic substance metabolic process; ","GO:0044421 extracellular region part; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0005925 focal adhesion; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0098791 Golgi subcompartment; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0030496 midbody; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005802 trans-Golgi network; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0031984 organelle subcompartment; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0008238 exopeptidase activity; GO:0008233 peptidase activity; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0008235 metalloexopeptidase activity; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0004177 aminopeptidase activity; GO:0016787 hydrolase activity; GO:0008237 metallopeptidase activity; GO:0030145 manganese ion binding; ","K11142","LAP3; cytosol aminopeptidase [EC:3.4.11.1 3.4.11.5]","hsa00480 Glutathione metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00330 Arginine and proline metabolism - Homo sapiens (human); ","IPR000819; IPR008283; ","\"Peptidase M17, leucyl aminopeptidase, C-terminal; Peptidase M17, leucyl aminopeptidase, N-terminal; \"\r"]
["P29034","Protein S100-A2 OS=Homo sapiens OX=9606 GN=S100A2","S100A2",11.117,31.993,27.6,6,12,6,0.399,0.397,0.423,1.605,1.591,1.56,3.902,2.05E-7,"extracellular\r","GO:0016477 cell migration; GO:0044707 single-multicellular organism process; GO:0090130 tissue migration; GO:0051674 localization of cell; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0090132 epithelium migration; GO:0048870 cell motility; GO:0032501 multicellular organismal process; GO:0043542 endothelial cell migration; GO:0010631 epithelial cell migration; GO:0001667 ameboidal-type cell migration; GO:0006928 movement of cell or subcellular component; GO:0040011 locomotion; GO:0051179 localization; GO:0009987 cellular process; ",null,"GO:0042802 identical protein binding; GO:0046914 transition metal ion binding; GO:0005488 binding; GO:0043167 ion binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0005509 calcium ion binding; ",{"$nulls":3},"IPR034325; IPR011992; IPR002048; IPR013787; ","\"S-100; EF-hand domain pair; EF-hand domain; S100/CaBP-9k-type, calcium binding, subdomain; \"\r"]
["P29350","Tyrosine-protein phosphatase non-receptor type 6 OS=Homo sapiens OX=9606 GN=PTPN6","PTPN6",67.56,45.509,16.8,8,11,8,0.925,1.008,0.849,1.077,0.934,1.108,1.121,0.191,"cytoplasm\r","GO:0044700 single organism signaling; GO:0002694 regulation of leukocyte activation; GO:0050672 negative regulation of lymphocyte proliferation; GO:0002698 negative regulation of immune effector process; GO:0018212 peptidyl-tyrosine modification; GO:0031347 regulation of defense response; GO:0044237 cellular metabolic process; GO:0050855 regulation of B cell receptor signaling pathway; GO:0010564 regulation of cell cycle process; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0008152 metabolic process; GO:0045577 regulation of B cell differentiation; GO:0070664 negative regulation of leukocyte proliferation; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0001906 cell killing; GO:0051716 cellular response to stimulus; GO:0000278 mitotic cell cycle; GO:0042325 regulation of phosphorylation; GO:0030168 platelet activation; GO:0080090 regulation of primary metabolic process; GO:0050864 regulation of B cell activation; GO:1903038 negative regulation of leukocyte cell-cell adhesion; GO:0044763 single-organism cellular process; GO:0002520 immune system development; GO:0048870 cell motility; GO:0043086 negative regulation of catalytic activity; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0002889 regulation of immunoglobulin mediated immune response; GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin; GO:0002923 regulation of humoral immune response mediated by circulating immunoglobulin; GO:1902532 negative regulation of intracellular signal transduction; GO:0048583 regulation of response to stimulus; GO:0098602 single organism cell adhesion; GO:0044260 cellular macromolecule metabolic process; GO:0016310 phosphorylation; GO:0044707 single-multicellular organism process; GO:0043407 negative regulation of MAP kinase activity; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0002920 regulation of humoral immune response; GO:0022408 negative regulation of cell-cell adhesion; GO:0048519 negative regulation of biological process; GO:1903706 regulation of hemopoiesis; GO:0009653 anatomical structure morphogenesis; GO:0050867 positive regulation of cell activation; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:0010959 regulation of metal ion transport; GO:0002449 lymphocyte mediated immunity; GO:0050778 positive regulation of immune response; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0051282 regulation of sequestering of calcium ion; GO:0045785 positive regulation of cell adhesion; GO:0006950 response to stress; GO:0051924 regulation of calcium ion transport; GO:0008283 cell proliferation; GO:0002376 immune system process; GO:0002263 cell activation involved in immune response; GO:1903039 positive regulation of leukocyte cell-cell adhesion; GO:0060348 bone development; GO:0007186 G-protein coupled receptor signaling pathway; GO:0002696 positive regulation of leukocyte activation; GO:0045055 regulated exocytosis; GO:0043412 macromolecule modification; GO:0006955 immune response; GO:0045936 negative regulation of phosphate metabolic process; GO:0008284 positive regulation of cell proliferation; GO:2000045 regulation of G1/S transition of mitotic cell cycle; GO:0051674 localization of cell; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0050858 negative regulation of antigen receptor-mediated signaling pathway; GO:0006796 phosphate-containing compound metabolic process; GO:0031400 negative regulation of protein modification process; GO:0009611 response to wounding; GO:0016337 single organismal cell-cell adhesion; GO:0007165 signal transduction; GO:0002890 negative regulation of immunoglobulin mediated immune response; GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling; GO:0002819 regulation of adaptive immune response; GO:0006915 apoptotic process; GO:1902806 regulation of cell cycle G1/S phase transition; GO:0070663 regulation of leukocyte proliferation; GO:0050777 negative regulation of immune response; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0002695 negative regulation of leukocyte activation; GO:0051726 regulation of cell cycle; GO:0030219 megakaryocyte differentiation; GO:0051279 regulation of release of sequestered calcium ion into cytosol; GO:0098609 cell-cell adhesion; GO:0030220 platelet formation; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0050853 B cell receptor signaling pathway; GO:0002820 negative regulation of adaptive immune response; GO:0032940 secretion by cell; GO:1902105 regulation of leukocyte differentiation; GO:0050856 regulation of T cell receptor signaling pathway; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0060338 regulation of type I interferon-mediated signaling pathway; GO:0006952 defense response; GO:0036211 protein modification process; GO:0050868 negative regulation of T cell activation; GO:0033630 positive regulation of cell adhesion mediated by integrin; GO:0043549 regulation of kinase activity; GO:0016477 cell migration; GO:0016043 cellular component organization; GO:2000021 regulation of ion homeostasis; GO:0051250 negative regulation of lymphocyte activation; GO:0060255 regulation of macromolecule metabolic process; GO:0001959 regulation of cytokine-mediated signaling pathway; GO:0002704 negative regulation of leukocyte mediated immunity; GO:0002921 negative regulation of humoral immune response; GO:0045087 innate immune response; GO:0000904 cell morphogenesis involved in differentiation; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0006468 protein phosphorylation; GO:0043408 regulation of MAPK cascade; GO:0023056 positive regulation of signaling; GO:0002757 immune response-activating signal transduction; GO:0010647 positive regulation of cell communication; GO:0045595 regulation of cell differentiation; GO:0050878 regulation of body fluid levels; GO:0035335 peptidyl-tyrosine dephosphorylation; GO:0035556 intracellular signal transduction; GO:0031295 T cell costimulation; GO:0051049 regulation of transport; GO:0036344 platelet morphogenesis; GO:0090279 regulation of calcium ion import; GO:0033628 regulation of cell adhesion mediated by integrin; GO:0001932 regulation of protein phosphorylation; GO:0006470 protein dephosphorylation; GO:0030097 hemopoiesis; GO:0022407 regulation of cell-cell adhesion; GO:0045619 regulation of lymphocyte differentiation; GO:0002703 regulation of leukocyte mediated immunity; GO:0018193 peptidyl-amino acid modification; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0034765 regulation of ion transmembrane transport; GO:0008219 cell death; GO:0002684 positive regulation of immune system process; GO:0010563 negative regulation of phosphorus metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0065008 regulation of biological quality; GO:0007596 blood coagulation; GO:0032944 regulation of mononuclear cell proliferation; GO:0045321 leukocyte activation; GO:0007166 cell surface receptor signaling pathway; GO:0032989 cellular component morphogenesis; GO:0033277 abortive mitotic cell cycle; GO:0008285 negative regulation of cell proliferation; GO:0022610 biological adhesion; GO:0061515 myeloid cell development; GO:0032879 regulation of localization; GO:0007155 cell adhesion; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0002244 hematopoietic progenitor cell differentiation; GO:0051174 regulation of phosphorus metabolic process; GO:0002443 leukocyte mediated immunity; GO:0043269 regulation of ion transport; GO:0050670 regulation of lymphocyte proliferation; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0034762 regulation of transmembrane transport; GO:0000902 cell morphogenesis; GO:0048513 animal organ development; GO:0050900 leukocyte migration; GO:0001909 leukocyte mediated cytotoxicity; GO:0060759 regulation of response to cytokine stimulus; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0002682 regulation of immune system process; GO:0006464 cellular protein modification process; GO:0050817 coagulation; GO:0050794 regulation of cellular process; GO:0007346 regulation of mitotic cell cycle; GO:0007162 negative regulation of cell adhesion; GO:0002283 neutrophil activation involved in immune response; GO:0042127 regulation of cell proliferation; GO:0031399 regulation of protein modification process; GO:0050860 negative regulation of T cell receptor signaling pathway; GO:0044267 cellular protein metabolic process; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0032844 regulation of homeostatic process; GO:0034109 homotypic cell-cell adhesion; GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0051239 regulation of multicellular organismal process; GO:0060341 regulation of cellular localization; GO:0050866 negative regulation of cell activation; GO:0070372 regulation of ERK1 and ERK2 cascade; GO:0014066 regulation of phosphatidylinositol 3-kinase signaling; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:1901987 regulation of cell cycle phase transition; GO:0051338 regulation of transferase activity; GO:0002707 negative regulation of lymphocyte mediated immunity; GO:0001933 negative regulation of protein phosphorylation; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:1904062 regulation of cation transmembrane transport; GO:0002253 activation of immune response; GO:1902531 regulation of intracellular signal transduction; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0098751 bone cell development; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation; GO:0030155 regulation of cell adhesion; GO:0006793 phosphorus metabolic process; GO:0050870 positive regulation of T cell activation; GO:0043409 negative regulation of MAPK cascade; GO:0006928 movement of cell or subcellular component; GO:0001775 cell activation; GO:0012501 programmed cell death; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0002713 negative regulation of B cell mediated immunity; GO:0050793 regulation of developmental process; GO:0006887 exocytosis; GO:0050863 regulation of T cell activation; GO:1902533 positive regulation of intracellular signal transduction; GO:0042130 negative regulation of T cell proliferation; GO:0031294 lymphocyte costimulation; GO:0051249 regulation of lymphocyte activation; GO:0051234 establishment of localization; GO:0010646 regulation of cell communication; GO:0071901 negative regulation of protein serine/threonine kinase activity; GO:0007154 cell communication; GO:0045088 regulation of innate immune response; GO:0033673 negative regulation of kinase activity; GO:0002697 regulation of immune effector process; GO:0002274 myeloid leukocyte activation; GO:0050851 antigen receptor-mediated signaling pathway; GO:0032502 developmental process; GO:0002228 natural killer cell mediated immunity; GO:0002446 neutrophil mediated immunity; GO:0048522 positive regulation of cellular process; GO:0051251 positive regulation of lymphocyte activation; GO:0051348 negative regulation of transferase activity; GO:0018108 peptidyl-tyrosine phosphorylation; GO:0002683 negative regulation of immune system process; GO:0050865 regulation of cell activation; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0019222 regulation of metabolic process; GO:0006469 negative regulation of protein kinase activity; GO:0040011 locomotion; GO:0019220 regulation of phosphate metabolic process; GO:0043299 leukocyte degranulation; GO:0048856 anatomical structure development; GO:0070527 platelet aggregation; GO:0001501 skeletal system development; GO:2000026 regulation of multicellular organismal development; GO:0045859 regulation of protein kinase activity; GO:0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0002252 immune effector process; GO:0050730 regulation of peptidyl-tyrosine phosphorylation; GO:0043405 regulation of MAP kinase activity; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0002706 regulation of lymphocyte mediated immunity; GO:0007599 hemostasis; GO:0048468 cell development; GO:0042267 natural killer cell mediated cytotoxicity; GO:0050854 regulation of antigen receptor-mediated signaling pathway; GO:0042326 negative regulation of phosphorylation; GO:1903169 regulation of calcium ion transmembrane transport; GO:0050859 negative regulation of B cell receptor signaling pathway; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0030099 myeloid cell differentiation; GO:0022409 positive regulation of cell-cell adhesion; GO:0002712 regulation of B cell mediated immunity; GO:0042129 regulation of T cell proliferation; GO:0032945 negative regulation of mononuclear cell proliferation; GO:0048585 negative regulation of response to stimulus; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0016311 dephosphorylation; GO:0048534 hematopoietic or lymphoid organ development; GO:0035855 megakaryocyte development; GO:0042060 wound healing; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0010522 regulation of calcium ion transport into cytosol; GO:0009967 positive regulation of signal transduction; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0016020 membrane; GO:1904724 tertiary granule lumen; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005911 cell-cell junction; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0042101 T cell receptor complex; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0098802 plasma membrane receptor complex; GO:0070820 tertiary granule; GO:0044446 intracellular organelle part; GO:0043235 receptor complex; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0044459 plasma membrane part; GO:0035580 specific granule lumen; GO:0042105 alpha-beta T cell receptor complex; GO:0042581 specific granule; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0038023 signaling receptor activity; GO:0016791 phosphatase activity; GO:0019901 protein kinase binding; GO:0045309 protein phosphorylated amino acid binding; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0004721 phosphoprotein phosphatase activity; GO:0004888 transmembrane signaling receptor activity; GO:0019900 kinase binding; GO:0004871 signal transducer activity; GO:0017124 SH3 domain binding; GO:0051219 phosphoprotein binding; GO:0050839 cell adhesion molecule binding; GO:0060089 molecular transducer activity; GO:0005001 transmembrane receptor protein tyrosine phosphatase activity; GO:0004872 receptor activity; GO:0004725 protein tyrosine phosphatase activity; GO:0042578 phosphoric ester hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0042169 SH2 domain binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0001784 phosphotyrosine binding; GO:0019904 protein domain specific binding; GO:0019198 transmembrane receptor protein phosphatase activity; GO:0019899 enzyme binding; GO:0099600 transmembrane receptor activity; ","K05697","PTPN6; tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]","hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa04520 Adherens junction - Homo sapiens (human); hsa04650 Natural killer cell mediated cytotoxicity - Homo sapiens (human); hsa04660 T cell receptor signaling pathway - Homo sapiens (human); hsa04662 B cell receptor signaling pathway - Homo sapiens (human); hsa05140 Leishmaniasis - Homo sapiens (human); hsa04630 Jak-STAT signaling pathway - Homo sapiens (human); ","IPR029021; IPR000387; IPR000980; IPR003595; IPR000242; ","\"Protein-tyrosine phosphatase-like; Tyrosine specific protein phosphatases domain; SH2 domain; Protein-tyrosine phosphatase, catalytic; PTP type protein phosphatase; \"\r"]
["P29401","Transketolase OS=Homo sapiens OX=9606 GN=TKT","TKT",67.877,265.6,44.6,24,60,24,1.057,1.017,1.037,0.957,0.983,0.968,0.935,0.00768,"cytoplasm\r","GO:0006739 NADP metabolic process; GO:0016051 carbohydrate biosynthetic process; GO:0019362 pyridine nucleotide metabolic process; GO:0040008 regulation of growth; GO:0006725 cellular aromatic compound metabolic process; GO:0046496 nicotinamide nucleotide metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0046364 monosaccharide biosynthetic process; GO:0044237 cellular metabolic process; GO:0072524 pyridine-containing compound metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0051156 glucose 6-phosphate metabolic process; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0046483 heterocycle metabolic process; GO:0019682 glyceraldehyde-3-phosphate metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0005996 monosaccharide metabolic process; GO:0019693 ribose phosphate metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0006098 pentose-phosphate shunt; GO:0034641 cellular nitrogen compound metabolic process; GO:0046184 aldehyde biosynthetic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0019321 pentose metabolic process; GO:0019322 pentose biosynthetic process; GO:0005999 xylulose biosynthetic process; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0044711 single-organism biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0006081 cellular aldehyde metabolic process; GO:0006732 coenzyme metabolic process; GO:0009052 pentose-phosphate shunt, non-oxidative branch; GO:0005975 carbohydrate metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0051186 cofactor metabolic process; GO:0090407 organophosphate biosynthetic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0050789 regulation of biological process; GO:0046166 glyceraldehyde-3-phosphate biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0044283 small molecule biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0005997 xylulose metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0043209 myelin sheath; GO:0005622 intracellular; GO:0044464 cell part; GO:0042579 microbody; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005777 peroxisome; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0016744 transferase activity, transferring aldehyde or ketonic groups; GO:0043167 ion binding; GO:0046983 protein dimerization activity; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0016740 transferase activity; GO:0048037 cofactor binding; GO:0004802 transketolase activity; ","K00615","E2.2.1.1; transketolase [EC:2.2.1.1]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00030 Pentose phosphate pathway - Homo sapiens (human); hsa01230 Biosynthesis of amino acids - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); ","IPR005474; IPR009014; IPR033248; IPR005475; IPR029061; ","\"Transketolase, N-terminal; Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II; Transketolase, C-terminal domain; Transketolase-like, pyrimidine-binding domain; Thiamin diphosphate-binding fold; \"\r"]
["P29536","Leiomodin-1 OS=Homo sapiens OX=9606 GN=LMOD1","LMOD1",67.029,33.452,8.3,5,6,5,1.106,1.038,1.137,0.942,0.876,0.898,0.828,0.00536,"nucleus\r","GO:0050794 regulation of cellular process; GO:0030833 regulation of actin filament polymerization; GO:0016043 cellular component organization; GO:0003012 muscle system process; GO:0065008 regulation of biological quality; GO:0032273 positive regulation of protein polymerization; GO:0051694 pointed-end actin filament capping; GO:0030835 negative regulation of actin filament depolymerization; GO:0032956 regulation of actin cytoskeleton organization; GO:0051129 negative regulation of cellular component organization; GO:0007015 actin filament organization; GO:0044699 single-organism process; GO:0044087 regulation of cellular component biogenesis; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0030832 regulation of actin filament length; GO:0051130 positive regulation of cellular component organization; GO:1901880 negative regulation of protein depolymerization; GO:0051693 actin filament capping; GO:0030036 actin cytoskeleton organization; GO:0006936 muscle contraction; GO:0045010 actin nucleation; GO:0032535 regulation of cellular component size; GO:0032271 regulation of protein polymerization; GO:0031334 positive regulation of protein complex assembly; GO:0051493 regulation of cytoskeleton organization; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0031333 negative regulation of protein complex assembly; GO:0003008 system process; GO:0051495 positive regulation of cytoskeleton organization; GO:1901879 regulation of protein depolymerization; GO:0051494 negative regulation of cytoskeleton organization; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0033043 regulation of organelle organization; GO:0032970 regulation of actin filament-based process; GO:0030838 positive regulation of actin filament polymerization; GO:0048518 positive regulation of biological process; GO:0032501 multicellular organismal process; GO:1902589 single-organism organelle organization; GO:0008064 regulation of actin polymerization or depolymerization; GO:0010639 negative regulation of organelle organization; GO:0043254 regulation of protein complex assembly; GO:0050789 regulation of biological process; GO:0010638 positive regulation of organelle organization; GO:0006996 organelle organization; GO:0043242 negative regulation of protein complex disassembly; GO:0030029 actin filament-based process; GO:1902904 negative regulation of supramolecular fiber organization; GO:0090066 regulation of anatomical structure size; GO:1902905 positive regulation of supramolecular fiber organization; GO:0030837 negative regulation of actin filament polymerization; GO:0043244 regulation of protein complex disassembly; GO:0051128 regulation of cellular component organization; GO:0030834 regulation of actin filament depolymerization; GO:0032272 negative regulation of protein polymerization; GO:0097435 supramolecular fiber organization; GO:0044089 positive regulation of cellular component biogenesis; GO:1902903 regulation of supramolecular fiber organization; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0099513 polymeric cytoskeletal fiber; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0030016 myofibril; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0015629 actin cytoskeleton; GO:0044422 organelle part; GO:0099081 supramolecular polymer; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0005856 cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0030017 sarcomere; GO:0043292 contractile fiber; GO:0005884 actin filament; GO:0044449 contractile fiber part; GO:0044444 cytoplasmic part; ","GO:0003779 actin binding; GO:0005523 tropomyosin binding; GO:0005515 protein binding; GO:0008092 cytoskeletal protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR003124; IPR032675; ","\"WH2 domain; Leucine-rich repeat domain, L domain-like; \"\r"]
["P29558","RNA-binding motif, single-stranded-interacting protein 1 OS=Homo sapiens OX=9606 GN=RBMS1","RBMS1",44.505,17.977,9.9,3,3,3,1.038,0.817,1.124,0.999,1.002,1.021,1.014,0.831,"nucleus\r","GO:0006396 RNA processing; GO:0006260 DNA replication; GO:0006725 cellular aromatic compound metabolic process; GO:0006259 DNA metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0009058 biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044237 cellular metabolic process; GO:0044249 cellular biosynthetic process; GO:0071704 organic substance metabolic process; GO:0016070 RNA metabolic process; GO:0008152 metabolic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0090304 nucleic acid metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003677 DNA binding; GO:0003723 RNA binding; GO:1901265 nucleoside phosphate binding; GO:0003690 double-stranded DNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0003697 single-stranded DNA binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0036094 small molecule binding; ",{"$nulls":3},"IPR000504; IPR012677; ","RNA recognition motif domain; Nucleotide-binding alpha-beta plait domain; \r"]
["P29762","Cellular retinoic acid-binding protein 1 OS=Homo sapiens OX=9606 GN=CRABP1","CRABP1",15.565,4.5523,13.9,2,2,2,1.235,1.166,1.208,0.854,0.824,0.749,0.672,0.000725,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0044707 single-multicellular organism process; GO:0065008 regulation of biological quality; GO:0042573 retinoic acid metabolic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0016115 terpenoid catabolic process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0051234 establishment of localization; GO:0006775 fat-soluble vitamin metabolic process; GO:0007165 signal transduction; GO:0006766 vitamin metabolic process; GO:0008152 metabolic process; GO:0042363 fat-soluble vitamin catabolic process; GO:0007154 cell communication; GO:0044248 cellular catabolic process; GO:0001523 retinoid metabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0008300 isoprenoid catabolic process; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0006629 lipid metabolic process; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0016042 lipid catabolic process; GO:0042445 hormone metabolic process; GO:0034653 retinoic acid catabolic process; GO:0006720 isoprenoid metabolic process; GO:0016103 diterpenoid catabolic process; GO:0044712 single-organism catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0072329 monocarboxylic acid catabolic process; GO:0044282 small molecule catabolic process; GO:0023052 signaling; GO:0044238 primary metabolic process; GO:0032501 multicellular organismal process; GO:0034754 cellular hormone metabolic process; GO:0046395 carboxylic acid catabolic process; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0050789 regulation of biological process; GO:0044767 single-organism developmental process; GO:0044710 single-organism metabolic process; GO:0009111 vitamin catabolic process; GO:0019752 carboxylic acid metabolic process; GO:0016054 organic acid catabolic process; GO:0044242 cellular lipid catabolic process; GO:0010817 regulation of hormone levels; GO:0006721 terpenoid metabolic process; GO:0016101 diterpenoid metabolic process; GO:0006082 organic acid metabolic process; GO:0051179 localization; GO:0048856 anatomical structure development; GO:0009056 catabolic process; GO:0043436 oxoacid metabolic process; GO:0065007 biological regulation; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0044444 cytoplasmic part; ","GO:0019842 vitamin binding; GO:0043167 ion binding; GO:0019841 retinol binding; GO:0005501 retinoid binding; GO:0043177 organic acid binding; GO:0005515 protein binding; GO:0019840 isoprenoid binding; GO:0033293 monocarboxylic acid binding; GO:0031406 carboxylic acid binding; GO:0043178 alcohol binding; GO:0005488 binding; GO:0008289 lipid binding; GO:0043168 anion binding; GO:0016918 retinal binding; GO:0001972 retinoic acid binding; GO:0005215 transporter activity; GO:0036094 small molecule binding; ","K17337",null,null,"IPR000463; IPR000566; IPR012674; IPR011038; ","Cytosolic fatty-acid binding; Lipocalin/cytosolic fatty-acid binding domain; Calycin; Calycin-like; \r"]
["P29966","Myristoylated alanine-rich C-kinase substrate OS=Homo sapiens OX=9606 GN=MARCKS","MARCKS",31.554,56.675,21.1,6,12,6,0.834,0.844,0.798,1.168,1.129,1.212,1.417,0.000199,"nucleus\r","GO:0050794 regulation of cellular process; GO:0090087 regulation of peptide transport; GO:0065008 regulation of biological quality; GO:0051049 regulation of transport; GO:0050796 regulation of insulin secretion; GO:0023051 regulation of signaling; GO:0051046 regulation of secretion; GO:1903530 regulation of secretion by cell; GO:0070201 regulation of establishment of protein localization; GO:0002791 regulation of peptide secretion; GO:0046883 regulation of hormone secretion; GO:0050789 regulation of biological process; GO:0010646 regulation of cell communication; GO:0032879 regulation of localization; GO:0090276 regulation of peptide hormone secretion; GO:0010817 regulation of hormone levels; GO:0051223 regulation of protein transport; GO:0032880 regulation of protein localization; GO:0050708 regulation of protein secretion; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005938 cell cortex; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0099568 cytoplasmic region; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0042585 germinal vesicle; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005856 cytoskeleton; GO:0005815 microtubule organizing center; GO:0005925 focal adhesion; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0015629 actin cytoskeleton; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0001674 female germ cell nucleus; GO:0043226 organelle; GO:0005634 nucleus; GO:0005813 centrosome; GO:0043073 germ cell nucleus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0051015 actin filament binding; GO:0008092 cytoskeletal protein binding; GO:0005488 binding; GO:0019901 protein kinase binding; GO:0044877 macromolecular complex binding; GO:0003779 actin binding; GO:0005080 protein kinase C binding; GO:0005515 protein binding; GO:0019900 kinase binding; GO:0005516 calmodulin binding; GO:0019899 enzyme binding; GO:0032403 protein complex binding; ","K12561","MARCKS; myristoylated alanine-rich C-kinase substrate","hsa04666 Fc gamma R-mediated phagocytosis - Homo sapiens (human); hsa05206 MicroRNAs in cancer - Homo sapiens (human); "]
["P29992","Guanine nucleotide-binding protein subunit alpha-11 OS=Homo sapiens OX=9606 GN=GNA11","GNA11",42.123,26.161,24.8,8,10,5,1.082,1.156,1.147,0.83,0.917,0.89,0.779,2.3E-3,"cytoplasm\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0007596 blood coagulation; GO:0045634 regulation of melanocyte differentiation; GO:0044699 single-organism process; GO:0009611 response to wounding; GO:0009605 response to external stimulus; GO:0007213 G-protein coupled acetylcholine receptor signaling pathway; GO:0007165 signal transduction; GO:0007507 heart development; GO:0007154 cell communication; GO:0051606 detection of stimulus; GO:0042752 regulation of circadian rhythm; GO:0009314 response to radiation; GO:0001508 action potential; GO:0070887 cellular response to chemical stimulus; GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0009583 detection of light stimulus; GO:0071214 cellular response to abiotic stimulus; GO:0060359 response to ammonium ion; GO:0030168 platelet activation; GO:0007212 dopamine receptor signaling pathway; GO:0044763 single-organism cellular process; GO:1905145 cellular response to acetylcholine; GO:0071242 cellular response to ammonium ion; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0042391 regulation of membrane potential; GO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway; GO:0048513 animal organ development; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0009649 entrainment of circadian clock; GO:0060158 phospholipase C-activating dopamine receptor signaling pathway; GO:1901699 cellular response to nitrogen compound; GO:1901698 response to nitrogen compound; GO:1903831 signal transduction involved in cellular response to ammonium ion; GO:0050817 coagulation; GO:0048856 anatomical structure development; GO:0001501 skeletal system development; GO:1905144 response to acetylcholine; GO:0050794 regulation of cellular process; GO:0072359 circulatory system development; GO:0044707 single-multicellular organism process; GO:0009581 detection of external stimulus; GO:0071467 cellular response to pH; GO:0009628 response to abiotic stimulus; GO:1901700 response to oxygen-containing compound; GO:0048066 developmental pigmentation; GO:0050896 response to stimulus; GO:0007599 hemostasis; GO:0009268 response to pH; GO:0007275 multicellular organism development; GO:0009584 detection of visible light; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0050878 regulation of body fluid levels; GO:0009416 response to light stimulus; GO:0006950 response to stress; GO:0048731 system development; GO:0009582 detection of abiotic stimulus; GO:0007602 phototransduction; GO:0010033 response to organic substance; GO:0050932 regulation of pigment cell differentiation; GO:0007186 G-protein coupled receptor signaling pathway; GO:1901701 cellular response to oxygen-containing compound; GO:0042060 wound healing; GO:0044767 single-organism developmental process; GO:0048070 regulation of developmental pigmentation; GO:0095500 acetylcholine receptor signaling pathway; GO:0043473 pigmentation; GO:0001775 cell activation; GO:0007603 phototransduction, visible light; GO:0050793 regulation of developmental process; GO:0065007 biological regulation; GO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0019898 extrinsic component of membrane; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0097730 non-motile cilium; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0031234 extrinsic component of cytoplasmic side of plasma membrane; GO:0005623 cell; GO:0097731 9+0 non-motile cilium; GO:0009898 cytoplasmic side of plasma membrane; GO:0098562 cytoplasmic side of membrane; GO:0044422 organelle part; GO:0005765 lysosomal membrane; GO:0070062 extracellular exosome; GO:1902494 catalytic complex; GO:0044441 ciliary part; GO:0005834 heterotrimeric G-protein complex; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005764 lysosome; GO:0001750 photoreceptor outer segment; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0098552 side of membrane; GO:0000323 lytic vacuole; GO:0005929 cilium; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:1905360 GTPase complex; GO:0098588 bounding membrane of organelle; GO:0098797 plasma membrane protein complex; GO:0044446 intracellular organelle part; GO:0019897 extrinsic component of plasma membrane; GO:0044463 cell projection part; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044459 plasma membrane part; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0097733 photoreceptor cell cilium; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0005102 receptor binding; GO:0031683 G-protein beta/gamma-subunit complex binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0031826 type 2A serotonin receptor binding; GO:0005515 protein binding; GO:0004871 signal transducer activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0003924 GTPase activity; GO:0043169 cation binding; GO:0043168 anion binding; GO:0001664 G-protein coupled receptor binding; GO:0019001 guanyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005525 GTP binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0017076 purine nucleotide binding; GO:0031821 G-protein coupled serotonin receptor binding; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0046872 metal ion binding; GO:0032555 purine ribonucleotide binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; GO:0032403 protein complex binding; ","K04635","GNA11; guanine nucleotide-binding protein subunit alpha-11","hsa04925 Aldosterone synthesis and secretion - Homo sapiens (human); hsa05142 Chagas disease (American trypanosomiasis) - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa04934 Cushing's syndrome - Homo sapiens (human); hsa04540 Gap junction - Homo sapiens (human); hsa04912 GnRH signaling pathway - Homo sapiens (human); hsa05146 Amoebiasis - Homo sapiens (human); hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human); hsa04020 Calcium signaling pathway - Homo sapiens (human); hsa04270 Vascular smooth muscle contraction - Homo sapiens (human); hsa04730 Long-term depression - Homo sapiens (human); hsa04927 Cortisol synthesis and secretion - Homo sapiens (human); hsa04911 Insulin secretion - Homo sapiens (human); hsa04928 Parathyroid hormone synthesis, secretion and action - Homo sapiens (human); hsa04725 Cholinergic synapse - Homo sapiens (human); ","IPR027417; IPR011025; ","\"P-loop containing nucleoside triphosphate hydrolase; G protein alpha subunit, helical insertion; \"\r"]
["P30041","Peroxiredoxin-6 OS=Homo sapiens OX=9606 GN=PRDX6","PRDX6",25.035,205.88,69.6,16,35,16,1.033,1.013,1.034,0.954,1.002,0.939,0.94,0.0394,"mitochondria\r","GO:0050794 regulation of cellular process; GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0045454 cell redox homeostasis; GO:1901700 response to oxygen-containing compound; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0008152 metabolic process; GO:0042743 hydrogen peroxide metabolic process; GO:1990748 cellular detoxification; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0072593 reactive oxygen species metabolic process; GO:0006979 response to oxidative stress; GO:0044248 cellular catabolic process; GO:0098869 cellular oxidant detoxification; GO:0036230 granulocyte activation; GO:0042744 hydrogen peroxide catabolic process; GO:0009987 cellular process; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0006629 lipid metabolic process; GO:0016042 lipid catabolic process; GO:0002443 leukocyte mediated immunity; GO:0006950 response to stress; GO:0044712 single-organism catabolic process; GO:0055114 oxidation-reduction process; GO:0009636 response to toxic substance; GO:0002446 neutrophil mediated immunity; GO:0016192 vesicle-mediated transport; GO:0000302 response to reactive oxygen species; GO:0044763 single-organism cellular process; GO:0019725 cellular homeostasis; GO:0002376 immune system process; GO:0043312 neutrophil degranulation; GO:0044238 primary metabolic process; GO:0002263 cell activation involved in immune response; GO:0002444 myeloid leukocyte mediated immunity; GO:0006810 transport; GO:0002366 leukocyte activation involved in immune response; GO:1901575 organic substance catabolic process; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0032940 secretion by cell; GO:0044710 single-organism metabolic process; GO:0001775 cell activation; GO:0043299 leukocyte degranulation; GO:0051179 localization; GO:0006955 immune response; GO:0098754 detoxification; GO:0009056 catabolic process; GO:0006887 exocytosis; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0042582 azurophil granule; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0004602 glutathione peroxidase activity; GO:0031625 ubiquitin protein ligase binding; GO:0016209 antioxidant activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0016491 oxidoreductase activity; GO:0050839 cell adhesion molecule binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0051920 peroxiredoxin activity; GO:0045296 cadherin binding; GO:0004601 peroxidase activity; GO:0044389 ubiquitin-like protein ligase binding; GO:0019899 enzyme binding; GO:0016684 oxidoreductase activity, acting on peroxide as acceptor; ","K11188","PRDX6; peroxiredoxin 6, 1-Cys peroxiredoxin [EC:1.11.1.7 1.11.1.15 3.1.1.-]","hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR019479; IPR000866; IPR012336; IPR013766; ","\"Peroxiredoxin, C-terminal; Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant; Thioredoxin-like fold; Thioredoxin domain; \"\r"]
["P30044","Peroxiredoxin-5, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX5","PRDX5",22.086,169.35,55.6,9,28,9,1.026,1.078,1.131,0.932,0.863,0.919,0.839,0.00882,"cytoplasm\r","GO:0065008 regulation of biological quality; GO:0010941 regulation of cell death; GO:0019362 pyridine nucleotide metabolic process; GO:0009891 positive regulation of biosynthetic process; GO:0044237 cellular metabolic process; GO:0010466 negative regulation of peptidase activity; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0098869 cellular oxidant detoxification; GO:0052548 regulation of endopeptidase activity; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0044281 small molecule metabolic process; GO:0000302 response to reactive oxygen species; GO:0044763 single-organism cellular process; GO:0006732 coenzyme metabolic process; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0051341 regulation of oxidoreductase activity; GO:0048872 homeostasis of number of cells; GO:1903506 regulation of nucleic acid-templated transcription; GO:0051336 regulation of hydrolase activity; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0060548 negative regulation of cell death; GO:0070995 NADPH oxidation; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0033554 cellular response to stress; GO:0044707 single-multicellular organism process; GO:0010951 negative regulation of endopeptidase activity; GO:0046496 nicotinamide nucleotide metabolic process; GO:0045454 cell redox homeostasis; GO:1901700 response to oxygen-containing compound; GO:0043067 regulation of programmed cell death; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0060249 anatomical structure homeostasis; GO:0051239 regulation of multicellular organismal process; GO:0045892 negative regulation of transcription, DNA-templated; GO:0042743 hydrogen peroxide metabolic process; GO:1990748 cellular detoxification; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0044248 cellular catabolic process; GO:0044253 positive regulation of multicellular organismal metabolic process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0042744 hydrogen peroxide catabolic process; GO:0045861 negative regulation of proteolysis; GO:0006950 response to stress; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0032965 regulation of collagen biosynthetic process; GO:0009890 negative regulation of biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0016480 negative regulation of transcription from RNA polymerase III promoter; GO:0019637 organophosphate metabolic process; GO:0012501 programmed cell death; GO:0010712 regulation of collagen metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0006739 NADP metabolic process; GO:0044246 regulation of multicellular organismal metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0072524 pyridine-containing compound metabolic process; GO:0051253 negative regulation of RNA metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0048871 multicellular organismal homeostasis; GO:2001141 regulation of RNA biosynthetic process; GO:0009893 positive regulation of metabolic process; GO:0060785 regulation of apoptosis involved in tissue homeostasis; GO:0006753 nucleoside phosphate metabolic process; GO:0006915 apoptotic process; GO:0006979 response to oxidative stress; GO:0034599 cellular response to oxidative stress; GO:0070887 cellular response to chemical stimulus; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0010468 regulation of gene expression; GO:0034614 cellular response to reactive oxygen species; GO:0031326 regulation of cellular biosynthetic process; GO:0006733 oxidoreduction coenzyme metabolic process; GO:2000116 regulation of cysteine-type endopeptidase activity; GO:0048873 homeostasis of number of cells within a tissue; GO:0055114 oxidation-reduction process; GO:0009636 response to toxic substance; GO:1901360 organic cyclic compound metabolic process; GO:0019725 cellular homeostasis; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051186 cofactor metabolic process; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0042221 response to chemical; GO:0010714 positive regulation of collagen metabolic process; GO:0001894 tissue homeostasis; GO:0006954 inflammatory response; GO:1902679 negative regulation of RNA biosynthetic process; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0006952 defense response; GO:0052547 regulation of peptidase activity; GO:0098754 detoxification; GO:0043069 negative regulation of programmed cell death; GO:0006725 cellular aromatic compound metabolic process; GO:0032967 positive regulation of collagen biosynthetic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0051346 negative regulation of hydrolase activity; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0006359 regulation of transcription from RNA polymerase III promoter; GO:0043066 negative regulation of apoptotic process; GO:0051354 negative regulation of oxidoreductase activity; GO:0072593 reactive oxygen species metabolic process; GO:2000117 negative regulation of cysteine-type endopeptidase activity; GO:0034641 cellular nitrogen compound metabolic process; GO:2001057 reactive nitrogen species metabolic process; GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:1901701 cellular response to oxygen-containing compound; GO:0008219 cell death; GO:0051246 regulation of protein metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0009056 catabolic process; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044438 microbody part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0070013 intracellular organelle lumen; GO:0005782 peroxisomal matrix; GO:0005622 intracellular; GO:0044464 cell part; GO:0042579 microbody; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0005759 mitochondrial matrix; GO:0044429 mitochondrial part; GO:0044439 peroxisomal part; GO:0005777 peroxisome; GO:0044446 intracellular organelle part; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0031907 microbody lumen; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0003677 DNA binding; GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process; GO:0005102 receptor binding; GO:0061134 peptidase regulator activity; GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process; GO:0046983 protein dimerization activity; GO:0016209 antioxidant activity; GO:0001016 RNA polymerase III regulatory region DNA binding; GO:0005515 protein binding; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0004866 endopeptidase inhibitor activity; GO:0004869 cysteine-type endopeptidase inhibitor activity; GO:0016491 oxidoreductase activity; GO:1901363 heterocyclic compound binding; GO:0000975 regulatory region DNA binding; GO:0097159 organic cyclic compound binding; GO:0001067 regulatory region nucleic acid binding; GO:0030234 enzyme regulator activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0044212 transcription regulatory region DNA binding; GO:0008379 thioredoxin peroxidase activity; GO:0030414 peptidase inhibitor activity; GO:0003676 nucleic acid binding; GO:0051920 peroxiredoxin activity; GO:0061135 endopeptidase regulator activity; GO:0004601 peroxidase activity; GO:0072541 peroxynitrite reductase activity; GO:0016684 oxidoreductase activity, acting on peroxide as acceptor; ","K11187","PRDX5; peroxiredoxin 5, atypical 2-Cys peroxiredoxin [EC:1.11.1.15]","hsa04146 Peroxisome - Homo sapiens (human); ","IPR013740; IPR012336; IPR013766; ","Redoxin; Thioredoxin-like fold; Thioredoxin domain; \r"]
["P30048","Thioredoxin-dependent peroxide reductase, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX3","PRDX3",27.692,39.78,25,7,17,7,1.126,1.123,1.169,0.838,0.882,0.921,0.773,0.00102,"mitochondria\r","GO:0065008 regulation of biological quality; GO:0010941 regulation of cell death; GO:0022414 reproductive process; GO:0044237 cellular metabolic process; GO:0009607 response to biotic stimulus; GO:0009605 response to external stimulus; GO:0010466 negative regulation of peptidase activity; GO:0008152 metabolic process; GO:0044093 positive regulation of molecular function; GO:0044702 single organism reproductive process; GO:0044706 multi-multicellular organism process; GO:0098869 cellular oxidant detoxification; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0018158 protein oxidation; GO:0052548 regulation of endopeptidase activity; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0003006 developmental process involved in reproduction; GO:0080090 regulation of primary metabolic process; GO:0000302 response to reactive oxygen species; GO:0044763 single-organism cellular process; GO:0002520 immune system development; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0051092 positive regulation of NF-kappaB transcription factor activity; GO:0051336 regulation of hydrolase activity; GO:0051090 regulation of sequence-specific DNA binding transcription factor activity; GO:0044710 single-organism metabolic process; GO:0018198 peptidyl-cysteine modification; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0048609 multicellular organismal reproductive process; GO:0060548 negative regulation of cell death; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0000003 reproduction; GO:0033554 cellular response to stress; GO:0044707 single-multicellular organism process; GO:0010951 negative regulation of endopeptidase activity; GO:0060135 maternal process involved in female pregnancy; GO:0042127 regulation of cell proliferation; GO:0001890 placenta development; GO:0045454 cell redox homeostasis; GO:1901700 response to oxygen-containing compound; GO:0044267 cellular protein metabolic process; GO:0043067 regulation of programmed cell death; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0007565 female pregnancy; GO:0042743 hydrogen peroxide metabolic process; GO:1990748 cellular detoxification; GO:0009889 regulation of biosynthetic process; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0044248 cellular catabolic process; GO:0007275 multicellular organism development; GO:0061458 reproductive system development; GO:0042744 hydrogen peroxide catabolic process; GO:0009617 response to bacterium; GO:0045861 negative regulation of proteolysis; GO:0006950 response to stress; GO:0032496 response to lipopolysaccharide; GO:0048731 system development; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0042542 response to hydrogen peroxide; GO:0006996 organelle organization; GO:0012501 programmed cell death; GO:0043412 macromolecule modification; GO:0045936 negative regulation of phosphate metabolic process; GO:0008284 positive regulation of cell proliferation; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0001893 maternal placenta development; GO:2001141 regulation of RNA biosynthetic process; GO:0033673 negative regulation of kinase activity; GO:0006915 apoptotic process; GO:0007005 mitochondrion organization; GO:0006979 response to oxidative stress; GO:0010035 response to inorganic substance; GO:0034599 cellular response to oxidative stress; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0034614 cellular response to reactive oxygen species; GO:0031326 regulation of cellular biosynthetic process; GO:2000116 regulation of cysteine-type endopeptidase activity; GO:0002237 response to molecule of bacterial origin; GO:0055114 oxidation-reduction process; GO:0009636 response to toxic substance; GO:0048608 reproductive structure development; GO:0048522 positive regulation of cellular process; GO:0019725 cellular homeostasis; GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity; GO:0051348 negative regulation of transferase activity; GO:0010605 negative regulation of macromolecule metabolic process; GO:0042391 regulation of membrane potential; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0042221 response to chemical; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0052547 regulation of peptidase activity; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0098754 detoxification; GO:0043549 regulation of kinase activity; GO:0016043 cellular component organization; GO:0043069 negative regulation of programmed cell death; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0043207 response to external biotic stimulus; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0051346 negative regulation of hydrolase activity; GO:0071704 organic substance metabolic process; GO:0033993 response to lipid; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:0043066 negative regulation of apoptotic process; GO:0072593 reactive oxygen species metabolic process; GO:0042326 negative regulation of phosphorylation; GO:2000117 negative regulation of cysteine-type endopeptidase activity; GO:0018171 peptidyl-cysteine oxidation; GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0009987 cellular process; GO:0006355 regulation of transcription, DNA-templated; GO:0030099 myeloid cell differentiation; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0030097 hemopoiesis; GO:0048534 hematopoietic or lymphoid organ development; GO:0032504 multicellular organism reproduction; GO:0018193 peptidyl-amino acid modification; GO:1901701 cellular response to oxygen-containing compound; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0044703 multi-organism reproductive process; GO:0010563 negative regulation of phosphorus metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0009056 catabolic process; GO:0051881 regulation of mitochondrial membrane potential; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0070013 intracellular organelle lumen; GO:0043209 myelin sheath; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0005759 mitochondrial matrix; GO:0044429 mitochondrial part; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process; GO:0061134 peptidase regulator activity; GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process; GO:0019901 protein kinase binding; GO:0016209 antioxidant activity; GO:0005515 protein binding; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0019900 kinase binding; GO:0004866 endopeptidase inhibitor activity; GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor; GO:0004869 cysteine-type endopeptidase inhibitor activity; GO:0016491 oxidoreductase activity; GO:0042802 identical protein binding; GO:0030234 enzyme regulator activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0008379 thioredoxin peroxidase activity; GO:0030414 peptidase inhibitor activity; GO:0051920 peroxiredoxin activity; GO:0008785 alkyl hydroperoxide reductase activity; GO:0016667 oxidoreductase activity, acting on a sulfur group of donors; GO:0061135 endopeptidase regulator activity; GO:0008022 protein C-terminus binding; GO:0004601 peroxidase activity; GO:0019899 enzyme binding; GO:0016684 oxidoreductase activity, acting on peroxide as acceptor; ","K20011",null,null,"IPR019479; IPR000866; IPR013766; IPR012336; ","\"Peroxiredoxin, C-terminal; Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant; Thioredoxin domain; Thioredoxin-like fold; \"\r"]
["P30084","Enoyl-CoA hydratase, mitochondrial OS=Homo sapiens OX=9606 GN=ECHS1","ECHS1",31.387,83.333,44.8,13,20,13,1.155,1.138,1.033,0.897,0.957,0.949,0.843,0.0136,"mitochondria\r","GO:0034440 lipid oxidation; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0030258 lipid modification; GO:0044248 cellular catabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0009987 cellular process; GO:0006629 lipid metabolic process; GO:0016042 lipid catabolic process; GO:0019395 fatty acid oxidation; GO:0055114 oxidation-reduction process; GO:0044712 single-organism catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006635 fatty acid beta-oxidation; GO:0072329 monocarboxylic acid catabolic process; GO:0044282 small molecule catabolic process; GO:0006631 fatty acid metabolic process; GO:0044238 primary metabolic process; GO:0046395 carboxylic acid catabolic process; GO:1901575 organic substance catabolic process; GO:0044710 single-organism metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0016054 organic acid catabolic process; GO:0044242 cellular lipid catabolic process; GO:0006082 organic acid metabolic process; GO:0009062 fatty acid catabolic process; GO:0009056 catabolic process; GO:0043436 oxoacid metabolic process; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0016829 lyase activity; GO:0016836 hydro-lyase activity; GO:0005515 protein binding; GO:0003824 catalytic activity; GO:0016835 carbon-oxygen lyase activity; GO:0005488 binding; GO:0004300 enoyl-CoA hydratase activity; ","K07511","ECHS1; enoyl-CoA hydratase [EC:4.2.1.17]","hsa00280 Valine, leucine and isoleucine degradation - Homo sapiens (human); hsa00310 Lysine degradation - Homo sapiens (human); hsa00640 Propanoate metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa01212 Fatty acid metabolism - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); hsa00062 Fatty acid elongation - Homo sapiens (human); hsa00071 Fatty acid degradation - Homo sapiens (human); hsa00650 Butanoate metabolism - Homo sapiens (human); hsa00410 beta-Alanine metabolism - Homo sapiens (human); hsa00380 Tryptophan metabolism - Homo sapiens (human); ","IPR029045; ","ClpP/crotonase-like domain; \r"]
["P30101","Protein disulfide-isomerase A3 OS=Homo sapiens OX=9606 GN=PDIA3","PDIA3",56.782,281.04,54.9,31,68,31,1.021,1.009,1.011,0.968,0.98,0.976,0.962,0.0016,"endoplasmic reticulum\r","GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0065008 regulation of biological quality; GO:0072594 establishment of protein localization to organelle; GO:0017038 protein import; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0051169 nuclear transport; GO:2001238 positive regulation of extrinsic apoptotic signaling pathway; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006457 protein folding; GO:2001233 regulation of apoptotic signaling pathway; GO:0072595 maintenance of protein localization in organelle; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0070972 protein localization to endoplasmic reticulum; GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0033365 protein localization to organelle; GO:0006606 protein import into nucleus; GO:0051651 maintenance of location in cell; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0044765 single-organism transport; GO:0051220 cytoplasmic sequestering of protein; GO:0051716 cellular response to stimulus; GO:0032507 maintenance of protein location in cell; GO:0055114 oxidation-reduction process; GO:0048002 antigen processing and presentation of peptide antigen; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0019725 cellular homeostasis; GO:0023052 signaling; GO:1902582 single-organism intracellular transport; GO:0010942 positive regulation of cell death; GO:0006810 transport; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0050789 regulation of biological process; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:2001236 regulation of extrinsic apoptotic signaling pathway; GO:0006913 nucleocytoplasmic transport; GO:0043068 positive regulation of programmed cell death; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0033554 cellular response to stress; GO:0034976 response to endoplasmic reticulum stress; GO:1902593 single-organism nuclear import; GO:0045454 cell redox homeostasis; GO:0006621 protein retention in ER lumen; GO:0043067 regulation of programmed cell death; GO:0043065 positive regulation of apoptotic process; GO:0034975 protein folding in endoplasmic reticulum; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:1902578 single-organism localization; GO:0023056 positive regulation of signaling; GO:0006886 intracellular protein transport; GO:2001235 positive regulation of apoptotic signaling pathway; GO:0044744 protein targeting to nucleus; GO:1902580 single-organism cellular localization; GO:0006508 proteolysis; GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; GO:0051235 maintenance of location; GO:0010647 positive regulation of cell communication; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0009966 regulation of signal transduction; GO:0045185 maintenance of protein location; GO:0006950 response to stress; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:0071702 organic substance transport; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0019882 antigen processing and presentation; GO:0070727 cellular macromolecule localization; GO:0051170 nuclear import; GO:0035437 maintenance of protein localization in endoplasmic reticulum; GO:0009967 positive regulation of signal transduction; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:0034504 protein localization to nucleus; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0055038 recycling endosome membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0055037 recycling endosome; GO:0048770 pigment granule; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0005925 focal adhesion; GO:0070013 intracellular organelle lumen; GO:0043209 myelin sheath; GO:0044464 cell part; GO:0005622 intracellular; GO:0098805 whole membrane; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0030055 cell-substrate junction; GO:0030139 endocytic vesicle; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005788 endoplasmic reticulum lumen; GO:0097708 intracellular vesicle; GO:0010008 endosome membrane; GO:0098588 bounding membrane of organelle; GO:0042470 melanosome; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0012505 endomembrane system; GO:0045335 phagocytic vesicle; GO:0044440 endosomal part; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0044432 endoplasmic reticulum part; GO:0009986 cell surface; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0003723 RNA binding; GO:0008233 peptidase activity; GO:0004629 phospholipase C activity; GO:0008234 cysteine-type peptidase activity; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0003756 protein disulfide isomerase activity; GO:0016298 lipase activity; GO:0016491 oxidoreductase activity; GO:0004175 endopeptidase activity; GO:0015036 disulfide oxidoreductase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds; GO:0016853 isomerase activity; GO:0042578 phosphoric ester hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0016667 oxidoreductase activity, acting on a sulfur group of donors; GO:0004620 phospholipase activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0008081 phosphoric diester hydrolase activity; GO:0004197 cysteine-type endopeptidase activity; GO:0016860 intramolecular oxidoreductase activity; ","K08056","PDIA3; protein disulfide isomerase family A, member 3 [EC:5.3.4.1]","hsa04612 Antigen processing and presentation - Homo sapiens (human); hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); ","IPR005788; IPR013766; IPR012336; ","Disulphide isomerase; Thioredoxin domain; Thioredoxin-like fold; \r"]
["P30273","High affinity immunoglobulin epsilon receptor subunit gamma OS=Homo sapiens OX=9606 GN=FCER1G","FCER1G",9.6674,2.6496,10.5,1,1,1,0.697,0.73,0.732,1.384,1.179,1.256,1.769,3.21E-4,"extracellular\r","GO:0044700 single organism signaling; GO:0002694 regulation of leukocyte activation; GO:0010941 regulation of cell death; GO:0032680 regulation of tumor necrosis factor production; GO:0002292 T cell differentiation involved in immune response; GO:0002554 serotonin secretion by platelet; GO:0098542 defense response to other organism; GO:0031347 regulation of defense response; GO:0044237 cellular metabolic process; GO:0009607 response to biotic stimulus; GO:0042110 T cell activation; GO:0055098 response to low-density lipoprotein particle; GO:0008152 metabolic process; GO:0002532 production of molecular mediator involved in inflammatory response; GO:0055094 response to lipoprotein particle; GO:0001810 regulation of type I hypersensitivity; GO:0051716 cellular response to stimulus; GO:0030168 platelet activation; GO:0050729 positive regulation of inflammatory response; GO:0044763 single-organism cellular process; GO:0002520 immune system development; GO:0048870 cell motility; GO:0006935 chemotaxis; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0002351 serotonin production involved in inflammatory response; GO:0006810 transport; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0002889 regulation of immunoglobulin mediated immune response; GO:0002223 stimulatory C-type lectin receptor signaling pathway; GO:0048583 regulation of response to stimulus; GO:0002892 regulation of type II hypersensitivity; GO:0044260 cellular macromolecule metabolic process; GO:0032765 positive regulation of mast cell cytokine production; GO:0060548 negative regulation of cell death; GO:0044707 single-multicellular organism process; GO:0002718 regulation of cytokine production involved in immune response; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0001819 positive regulation of cytokine production; GO:0010543 regulation of platelet activation; GO:0017157 regulation of exocytosis; GO:0002576 platelet degranulation; GO:0048519 negative regulation of biological process; GO:0019724 B cell mediated immunity; GO:0030098 lymphocyte differentiation; GO:0050867 positive regulation of cell activation; GO:0097530 granulocyte migration; GO:0043300 regulation of leukocyte degranulation; GO:0001803 regulation of type III hypersensitivity; GO:1902580 single-organism cellular localization; GO:0034613 cellular protein localization; GO:0038093 Fc receptor signaling pathway; GO:0002449 lymphocyte mediated immunity; GO:0030217 T cell differentiation; GO:0050778 positive regulation of immune response; GO:0033025 regulation of mast cell apoptotic process; GO:0030100 regulation of endocytosis; GO:0006950 response to stress; GO:0002864 regulation of acute inflammatory response to antigenic stimulus; GO:0050766 positive regulation of phagocytosis; GO:0032101 regulation of response to external stimulus; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0033033 negative regulation of myeloid cell apoptotic process; GO:0002263 cell activation involved in immune response; GO:0002696 positive regulation of leukocyte activation; GO:0072659 protein localization to plasma membrane; GO:0045055 regulated exocytosis; GO:0061041 regulation of wound healing; GO:0001798 positive regulation of type IIa hypersensitivity; GO:0006955 immune response; GO:1903034 regulation of response to wounding; GO:2000107 negative regulation of leukocyte apoptotic process; GO:0010256 endomembrane system organization; GO:0015850 organic hydroxy compound transport; GO:0031623 receptor internalization; GO:0051674 localization of cell; GO:0048869 cellular developmental process; GO:0051046 regulation of secretion; GO:0044699 single-organism process; GO:0033003 regulation of mast cell activation; GO:0033032 regulation of myeloid cell apoptotic process; GO:0045576 mast cell activation; GO:0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response; GO:0002863 positive regulation of inflammatory response to antigenic stimulus; GO:0009611 response to wounding; GO:0007165 signal transduction; GO:0071621 granulocyte chemotaxis; GO:1903307 positive regulation of regulated secretory pathway; GO:0002819 regulation of adaptive immune response; GO:1900046 regulation of hemostasis; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0033036 macromolecule localization; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0002708 positive regulation of lymphocyte mediated immunity; GO:0071402 cellular response to lipoprotein particle stimulus; GO:0043112 receptor metabolic process; GO:0001796 regulation of type IIa hypersensitivity; GO:0002700 regulation of production of molecular mediator of immune response; GO:1903530 regulation of secretion by cell; GO:0043304 regulation of mast cell degranulation; GO:0007229 integrin-mediated signaling pathway; GO:0023052 signaling; GO:0002764 immune response-regulating signaling pathway; GO:0002444 myeloid leukocyte mediated immunity; GO:0030593 neutrophil chemotaxis; GO:0032940 secretion by cell; GO:0002705 positive regulation of leukocyte mediated immunity; GO:0006954 inflammatory response; GO:0002431 Fc receptor mediated stimulatory signaling pathway; GO:0006952 defense response; GO:0002891 positive regulation of immunoglobulin mediated immune response; GO:0016477 cell migration; GO:0016043 cellular component organization; GO:0001812 positive regulation of type I hypersensitivity; GO:0043069 negative regulation of programmed cell death; GO:0002885 positive regulation of hypersensitivity; GO:0071310 cellular response to organic substance; GO:0033026 negative regulation of mast cell apoptotic process; GO:0010324 membrane invagination; GO:0002673 regulation of acute inflammatory response; GO:0002286 T cell activation involved in immune response; GO:0051707 response to other organism; GO:0045087 innate immune response; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0043066 negative regulation of apoptotic process; GO:0002757 immune response-activating signal transduction; GO:0050878 regulation of body fluid levels; GO:0042742 defense response to bacterium; GO:0051049 regulation of transport; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:0002699 positive regulation of immune effector process; GO:0044802 single-organism membrane organization; GO:0030097 hemopoiesis; GO:0002703 regulation of leukocyte mediated immunity; GO:0002366 leukocyte activation involved in immune response; GO:0002720 positive regulation of cytokine production involved in immune response; GO:0032653 regulation of interleukin-10 production; GO:0019882 antigen processing and presentation; GO:2000106 regulation of leukocyte apoptotic process; GO:0042119 neutrophil activation; GO:0030595 leukocyte chemotaxis; GO:0071495 cellular response to endogenous stimulus; GO:0002684 positive regulation of immune system process; GO:0038095 Fc-epsilon receptor signaling pathway; GO:0050727 regulation of inflammatory response; GO:0001817 regulation of cytokine production; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0060627 regulation of vesicle-mediated transport; GO:0016064 immunoglobulin mediated immune response; GO:0065008 regulation of biological quality; GO:0007596 blood coagulation; GO:0045321 leukocyte activation; GO:0002220 innate immune response activating cell surface receptor signaling pathway; GO:0007166 cell surface receptor signaling pathway; GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0032760 positive regulation of tumor necrosis factor production; GO:0009605 response to external stimulus; GO:0006837 serotonin transport; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0009719 response to endogenous stimulus; GO:0043170 macromolecule metabolic process; GO:0008104 protein localization; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0002883 regulation of hypersensitivity; GO:0006911 phagocytosis, engulfment; GO:0032733 positive regulation of interleukin-10 production; GO:0002443 leukocyte mediated immunity; GO:0001820 serotonin secretion; GO:0033008 positive regulation of mast cell activation involved in immune response; GO:0072657 protein localization to membrane; GO:0002758 innate immune response-activating signal transduction; GO:0045921 positive regulation of exocytosis; GO:0015696 ammonium transport; GO:0007009 plasma membrane organization; GO:0032501 multicellular organismal process; GO:0048513 animal organ development; GO:0050900 leukocyte migration; GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; GO:0044710 single-organism metabolic process; GO:0002682 regulation of immune system process; GO:0042330 taxis; GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II; GO:0050817 coagulation; GO:0002821 positive regulation of adaptive immune response; GO:0051047 positive regulation of secretion; GO:0050794 regulation of cellular process; GO:0002283 neutrophil activation involved in immune response; GO:0043067 regulation of programmed cell death; GO:0030193 regulation of blood coagulation; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0002886 regulation of myeloid leukocyte mediated immunity; GO:0060326 cell chemotaxis; GO:0032844 regulation of homeostatic process; GO:0002894 positive regulation of type II hypersensitivity; GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0051239 regulation of multicellular organismal process; GO:1990778 protein localization to cell periphery; GO:0060341 regulation of cellular localization; GO:0099024 plasma membrane invagination; GO:0031349 positive regulation of defense response; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0001805 positive regulation of type III hypersensitivity; GO:0006898 receptor-mediated endocytosis; GO:0007275 multicellular organism development; GO:0009617 response to bacterium; GO:0002253 activation of immune response; GO:0002285 lymphocyte activation involved in immune response; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0032675 regulation of interleukin-6 production; GO:1903557 positive regulation of tumor necrosis factor superfamily cytokine production; GO:0071702 organic substance transport; GO:0006811 ion transport; GO:0061024 membrane organization; GO:0001775 cell activation; GO:0006928 movement of cell or subcellular component; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0006887 exocytosis; GO:0002702 positive regulation of production of molecular mediator of immune response; GO:0033005 positive regulation of mast cell activation; GO:0002675 positive regulation of acute inflammatory response; GO:1903555 regulation of tumor necrosis factor superfamily cytokine production; GO:0038094 Fc-gamma receptor signaling pathway; GO:0051234 establishment of localization; GO:0006909 phagocytosis; GO:0051130 positive regulation of cellular component organization; GO:1990266 neutrophil migration; GO:0002888 positive regulation of myeloid leukocyte mediated immunity; GO:0007154 cell communication; GO:0045088 regulation of innate immune response; GO:0097529 myeloid leukocyte migration; GO:0032763 regulation of mast cell cytokine production; GO:0002250 adaptive immune response; GO:0032103 positive regulation of response to external stimulus; GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I; GO:0002697 regulation of immune effector process; GO:0050764 regulation of phagocytosis; GO:0002442 serotonin secretion involved in inflammatory response; GO:0070887 cellular response to chemical stimulus; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:0002521 leukocyte differentiation; GO:0048002 antigen processing and presentation of peptide antigen; GO:0002446 neutrophil mediated immunity; GO:0048522 positive regulation of cellular process; GO:0032386 regulation of intracellular transport; GO:0002495 antigen processing and presentation of peptide antigen via MHC class II; GO:0015844 monoamine transport; GO:0051050 positive regulation of transport; GO:0002683 negative regulation of immune system process; GO:0050789 regulation of biological process; GO:0050865 regulation of cell activation; GO:0042221 response to chemical; GO:1903532 positive regulation of secretion by cell; GO:0043299 leukocyte degranulation; GO:0040011 locomotion; GO:0048856 anatomical structure development; GO:0002218 activation of innate immune response; GO:0043302 positive regulation of leukocyte degranulation; GO:0002252 immune effector process; GO:0045807 positive regulation of endocytosis; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0002706 regulation of lymphocyte mediated immunity; GO:0007599 hemostasis; GO:0033006 regulation of mast cell activation involved in immune response; GO:0006812 cation transport; GO:0036230 granulocyte activation; GO:0002714 positive regulation of B cell mediated immunity; GO:0009987 cellular process; GO:0071404 cellular response to low-density lipoprotein particle stimulus; GO:0032755 positive regulation of interleukin-6 production; GO:0045089 positive regulation of innate immune response; GO:0032388 positive regulation of intracellular transport; GO:0002712 regulation of B cell mediated immunity; GO:0002866 positive regulation of acute inflammatory response to antigenic stimulus; GO:0046649 lymphocyte activation; GO:0032845 negative regulation of homeostatic process; GO:1903305 regulation of regulated secretory pathway; GO:0006897 endocytosis; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0048534 hematopoietic or lymphoid organ development; GO:0051641 cellular localization; GO:0050818 regulation of coagulation; GO:0070727 cellular macromolecule localization; GO:0043306 positive regulation of mast cell degranulation; GO:0042060 wound healing; GO:0044767 single-organism developmental process; GO:0051128 regulation of cellular component organization; GO:0002861 regulation of inflammatory response to antigenic stimulus; GO:0071705 nitrogen compound transport; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0009897 external side of plasma membrane; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0098796 membrane protein complex; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0070821 tertiary granule membrane; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0099503 secretory vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0098552 side of membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0031226 intrinsic component of plasma membrane; GO:0098588 bounding membrane of organelle; GO:0098797 plasma membrane protein complex; GO:0070820 tertiary granule; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0032998 Fc-epsilon receptor I complex; GO:0032997 Fc receptor complex; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0030667 secretory granule membrane; GO:0044459 plasma membrane part; GO:0101003 ficolin-1-rich granule membrane; GO:0009986 cell surface; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0038023 signaling receptor activity; GO:0019865 immunoglobulin binding; GO:0044877 macromolecular complex binding; GO:0019763 immunoglobulin receptor activity; GO:0005515 protein binding; GO:0004888 transmembrane signaling receptor activity; GO:0004871 signal transducer activity; GO:0019863 IgE binding; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0005488 binding; GO:0019767 IgE receptor activity; GO:0099600 transmembrane receptor activity; GO:0032403 protein complex binding; GO:0019864 IgG binding; ","K07983","FCER1G; high affinity immunoglobulin epsilon receptor subunit gamma","hsa04611 Platelet activation - Homo sapiens (human); hsa04072 Phospholipase D signaling pathway - Homo sapiens (human); hsa05152 Tuberculosis - Homo sapiens (human); hsa04664 Fc epsilon RI signaling pathway - Homo sapiens (human); hsa04650 Natural killer cell mediated cytotoxicity - Homo sapiens (human); hsa04625 C-type lectin receptor signaling pathway - Homo sapiens (human); hsa04071 Sphingolipid signaling pathway - Homo sapiens (human); hsa05310 Asthma - Homo sapiens (human); "]
["P30405","Peptidyl-prolyl cis-trans isomerase F, mitochondrial OS=Homo sapiens OX=9606 GN=PPIF","PPIF",22.04,4.2325,15,4,5,2,0.935,0.958,0.893,1.045,1.176,0.992,1.153,0.0612,"mitochondria\r","GO:0065008 regulation of biological quality; GO:0010941 regulation of cell death; GO:0045980 negative regulation of nucleotide metabolic process; GO:0090201 negative regulation of release of cytochrome c from mitochondria; GO:0046685 response to arsenic-containing substance; GO:0044237 cellular metabolic process; GO:0002082 regulation of oxidative phosphorylation; GO:0010821 regulation of mitochondrion organization; GO:0045978 negative regulation of nucleoside metabolic process; GO:0008152 metabolic process; GO:0032879 regulation of localization; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0090559 regulation of membrane permeability; GO:0090324 negative regulation of oxidative phosphorylation; GO:0051051 negative regulation of transport; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:0000302 response to reactive oxygen species; GO:0044763 single-organism cellular process; GO:0043269 regulation of ion transport; GO:0031323 regulation of cellular metabolic process; GO:0043086 negative regulation of catalytic activity; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0006810 transport; GO:0034762 regulation of transmembrane transport; GO:1902532 negative regulation of intracellular signal transduction; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0032412 regulation of ion transmembrane transporter activity; GO:0060548 negative regulation of cell death; GO:0043068 positive regulation of programmed cell death; GO:0006140 regulation of nucleotide metabolic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0007006 mitochondrial membrane organization; GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity; GO:0044267 cellular protein metabolic process; GO:1901700 response to oxygen-containing compound; GO:0043067 regulation of programmed cell death; GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:2000275 regulation of oxidative phosphorylation uncoupler activity; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0051171 regulation of nitrogen compound metabolic process; GO:0009966 regulation of signal transduction; GO:1904062 regulation of cation transmembrane transport; GO:0032409 regulation of transporter activity; GO:0034763 negative regulation of transmembrane transport; GO:0010823 negative regulation of mitochondrion organization; GO:1902531 regulation of intracellular signal transduction; GO:0071243 cellular response to arsenic-containing substance; GO:0006950 response to stress; GO:0097300 programmed necrotic cell death; GO:0000413 protein peptidyl-prolyl isomerization; GO:0044238 primary metabolic process; GO:1903579 negative regulation of ATP metabolic process; GO:0009892 negative regulation of metabolic process; GO:0042542 response to hydrogen peroxide; GO:0006996 organelle organization; GO:1900543 negative regulation of purine nucleotide metabolic process; GO:0061024 membrane organization; GO:0012501 programmed cell death; GO:0048584 positive regulation of response to stimulus; GO:0070266 necroptotic process; GO:0043412 macromolecule modification; GO:0071248 cellular response to metal ion; GO:0051179 localization; GO:0045936 negative regulation of phosphate metabolic process; GO:0043467 regulation of generation of precursor metabolites and energy; GO:0009968 negative regulation of signal transduction; GO:0090199 regulation of release of cytochrome c from mitochondria; GO:0023051 regulation of signaling; GO:0051129 negative regulation of cellular component organization; GO:0006839 mitochondrial transport; GO:0044699 single-organism process; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0002931 response to ischemia; GO:0006457 protein folding; GO:2001233 regulation of apoptotic signaling pathway; GO:0032780 negative regulation of ATPase activity; GO:0010646 regulation of cell communication; GO:2001243 negative regulation of intrinsic apoptotic signaling pathway; GO:0007005 mitochondrion organization; GO:0006915 apoptotic process; GO:0006979 response to oxidative stress; GO:0034599 cellular response to oxidative stress; GO:0010035 response to inorganic substance; GO:0070887 cellular response to chemical stimulus; GO:0034614 cellular response to reactive oxygen species; GO:0070265 necrotic cell death; GO:0048522 positive regulation of cellular process; GO:0022898 regulation of transmembrane transporter activity; GO:0010038 response to metal ion; GO:0010942 positive regulation of cell death; GO:0010155 regulation of proton transport; GO:0010639 negative regulation of organelle organization; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0010638 positive regulation of organelle organization; GO:0043462 regulation of ATPase activity; GO:0071241 cellular response to inorganic substance; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0090200 positive regulation of release of cytochrome c from mitochondria; GO:0036211 protein modification process; GO:0016043 cellular component organization; GO:0043069 negative regulation of programmed cell death; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0043065 positive regulation of apoptotic process; GO:0009118 regulation of nucleoside metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0010849 regulation of proton-transporting ATPase activity, rotational mechanism; GO:0050896 response to stimulus; GO:0051346 negative regulation of hydrolase activity; GO:0071704 organic substance metabolic process; GO:0070301 cellular response to hydrogen peroxide; GO:0046902 regulation of mitochondrial membrane permeability; GO:0043066 negative regulation of apoptotic process; GO:0023056 positive regulation of signaling; GO:0042326 negative regulation of phosphorylation; GO:0032410 negative regulation of transporter activity; GO:2001235 positive regulation of apoptotic signaling pathway; GO:0051592 response to calcium ion; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:1903578 regulation of ATP metabolic process; GO:0010939 regulation of necrotic cell death; GO:0043271 negative regulation of ion transport; GO:0008637 apoptotic mitochondrial changes; GO:0051049 regulation of transport; GO:0071277 cellular response to calcium ion; GO:0044802 single-organism membrane organization; GO:0033043 regulation of organelle organization; GO:0048585 negative regulation of response to stimulus; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0018208 peptidyl-proline modification; GO:0048518 positive regulation of biological process; GO:0010822 positive regulation of mitochondrion organization; GO:0018193 peptidyl-amino acid modification; GO:1900542 regulation of purine nucleotide metabolic process; GO:1901701 cellular response to oxygen-containing compound; GO:0034765 regulation of ion transmembrane transport; GO:0008219 cell death; GO:2001242 regulation of intrinsic apoptotic signaling pathway; GO:0010563 negative regulation of phosphorus metabolic process; GO:0009967 positive regulation of signal transduction; GO:0051128 regulation of cellular component organization; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044429 mitochondrial part; GO:0031090 organelle membrane; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0031974 membrane-enclosed lumen; GO:0005740 mitochondrial envelope; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0031975 envelope; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0031966 mitochondrial membrane; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; ","GO:0003755 peptidyl-prolyl cis-trans isomerase activity; GO:0016853 isomerase activity; GO:0003824 catalytic activity; GO:0042277 peptide binding; GO:0005488 binding; GO:0005515 protein binding; GO:0008144 drug binding; GO:0033218 amide binding; GO:0016018 cyclosporin A binding; GO:0016859 cis-trans isomerase activity; ","K09565","PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]","hsa05016 Huntington's disease - Homo sapiens (human); hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human); hsa04020 Calcium signaling pathway - Homo sapiens (human); hsa05145 Toxoplasmosis - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); ","IPR002130; IPR029000; ","Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain; Cyclophilin-like domain; \r"]
["P30519","Heme oxygenase 2 OS=Homo sapiens OX=9606 GN=HMOX2","HMOX2",36.032,16.089,15.8,5,10,5,0.992,0.849,0.958,1.068,1.058,1.102,1.153,0.0413,"cytoplasm\r","GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0051187 cofactor catabolic process; GO:0033015 tetrapyrrole catabolic process; GO:0006979 response to oxidative stress; GO:0055065 metal ion homeostasis; GO:1901361 organic cyclic compound catabolic process; GO:0006788 heme oxidation; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0002443 leukocyte mediated immunity; GO:0050801 ion homeostasis; GO:0055114 oxidation-reduction process; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0098771 inorganic ion homeostasis; GO:1901360 organic cyclic compound metabolic process; GO:0019725 cellular homeostasis; GO:0002444 myeloid leukocyte mediated immunity; GO:0051186 cofactor metabolic process; GO:0046916 cellular transition metal ion homeostasis; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0046149 pigment catabolic process; GO:0006787 porphyrin-containing compound catabolic process; GO:0032940 secretion by cell; GO:0044710 single-organism metabolic process; GO:0033013 tetrapyrrole metabolic process; GO:0043299 leukocyte degranulation; GO:0006879 cellular iron ion homeostasis; GO:0055076 transition metal ion homeostasis; GO:0002283 neutrophil activation involved in immune response; GO:0006725 cellular aromatic compound metabolic process; GO:0002252 immune effector process; GO:0009628 response to abiotic stimulus; GO:0030003 cellular cation homeostasis; GO:0042167 heme catabolic process; GO:0055072 iron ion homeostasis; GO:0042168 heme metabolic process; GO:0050896 response to stimulus; GO:0055082 cellular chemical homeostasis; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0006778 porphyrin-containing compound metabolic process; GO:0046483 heterocycle metabolic process; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0055080 cation homeostasis; GO:0001666 response to hypoxia; GO:0070482 response to oxygen levels; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0006950 response to stress; GO:0042440 pigment metabolic process; GO:0044712 single-organism catabolic process; GO:0016192 vesicle-mediated transport; GO:0006807 nitrogen compound metabolic process; GO:0002376 immune system process; GO:0043312 neutrophil degranulation; GO:0002263 cell activation involved in immune response; GO:0002366 leukocyte activation involved in immune response; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:1901565 organonitrogen compound catabolic process; GO:0006873 cellular ion homeostasis; GO:0001775 cell activation; GO:0006875 cellular metal ion homeostasis; GO:0036293 response to decreased oxygen levels; GO:0051179 localization; GO:0006955 immune response; GO:0009056 catabolic process; GO:0006887 exocytosis; GO:0065007 biological regulation; GO:1901564 organonitrogen compound metabolic process; GO:0046700 heterocycle catabolic process; ","GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0099503 secretory vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0035579 specific granule membrane; GO:0005789 endoplasmic reticulum membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0030667 secretory granule membrane; GO:0044432 endoplasmic reticulum part; GO:0042581 specific granule; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0020037 heme binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; GO:0005515 protein binding; GO:0004392 heme oxygenase (decyclizing) activity; GO:0046906 tetrapyrrole binding; GO:0016491 oxidoreductase activity; ","K00510","HMOX1; heme oxygenase 1 [EC:1.14.14.18]","hsa04978 Mineral absorption - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa04066 HIF-1 signaling pathway - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa04216 Ferroptosis - Homo sapiens (human); hsa00860 Porphyrin and chlorophyll metabolism - Homo sapiens (human); hsa05225 Hepatocellular carcinoma - Homo sapiens (human); hsa05206 MicroRNAs in cancer - Homo sapiens (human); hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human); ","IPR016084; ","\"Haem oxygenase-like, multi-helical; \"\r"]
["P30566","Adenylosuccinate lyase OS=Homo sapiens OX=9606 GN=ADSL","ADSL",54.889,15.22,9.7,5,7,5,1.041,0.927,1.031,1.04,1.018,0.989,1.016,0.692,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009163 nucleoside biosynthetic process; GO:0046129 purine ribonucleoside biosynthetic process; GO:0009058 biosynthetic process; GO:0009156 ribonucleoside monophosphate biosynthetic process; GO:0046040 IMP metabolic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0046390 ribose phosphate biosynthetic process; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0044208 'de novo' AMP biosynthetic process; GO:0006091 generation of precursor metabolites and energy; GO:1901137 carbohydrate derivative biosynthetic process; GO:0051262 protein tetramerization; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0006753 nucleoside phosphate metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0018130 heterocycle biosynthetic process; GO:0071822 protein complex subunit organization; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0072521 purine-containing compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0009168 purine ribonucleoside monophosphate biosynthetic process; GO:0042451 purine nucleoside biosynthetic process; GO:0090407 organophosphate biosynthetic process; GO:0042221 response to chemical; GO:0014823 response to activity; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0072522 purine-containing compound biosynthetic process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0006188 IMP biosynthetic process; GO:1901657 glycosyl compound metabolic process; GO:0009126 purine nucleoside monophosphate metabolic process; GO:0070271 protein complex biogenesis; GO:0006164 purine nucleotide biosynthetic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0016043 cellular component organization; GO:0009165 nucleotide biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0009628 response to abiotic stimulus; GO:0009259 ribonucleotide metabolic process; GO:0014850 response to muscle activity; GO:0046033 AMP metabolic process; GO:0050896 response to stimulus; GO:1901566 organonitrogen compound biosynthetic process; GO:0051259 protein oligomerization; GO:0071704 organic substance metabolic process; GO:0009991 response to extracellular stimulus; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0001666 response to hypoxia; GO:0070482 response to oxygen levels; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009119 ribonucleoside metabolic process; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0009124 nucleoside monophosphate biosynthetic process; GO:0006950 response to stress; GO:0044711 single-organism biosynthetic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0009127 purine nucleoside monophosphate biosynthetic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0042455 ribonucleoside biosynthetic process; GO:0044238 primary metabolic process; GO:0007584 response to nutrient; GO:0045333 cellular respiration; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0006163 purine nucleotide metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0046128 purine ribonucleoside metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0009152 purine ribonucleotide biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0009060 aerobic respiration; GO:0006189 'de novo' IMP biosynthetic process; GO:1901659 glycosyl compound biosynthetic process; GO:0009260 ribonucleotide biosynthetic process; GO:0006167 AMP biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0042594 response to starvation; GO:0036293 response to decreased oxygen levels; GO:0009150 purine ribonucleotide metabolic process; GO:0031667 response to nutrient levels; GO:0071840 cellular component organization or biogenesis; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005829 cytosol; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044444 cytoplasmic part; ","GO:0016840 carbon-nitrogen lyase activity; GO:0016829 lyase activity; GO:0070626 (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; GO:0016842 amidine-lyase activity; GO:0004018 N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; GO:0003824 catalytic activity; ","K01756","purB; adenylosuccinate lyase [EC:4.3.2.2]","hsa00230 Purine metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00250 Alanine, aspartate and glutamate metabolism - Homo sapiens (human); ","IPR024083; IPR008948; IPR022761; IPR019468; ","\"Fumarase/histidase, N-terminal; L-Aspartase-like; Fumarate lyase, N-terminal; Adenylosuccinate lyase C-terminal; \"\r"]
["P30711","Glutathione S-transferase theta-1 OS=Homo sapiens OX=9606 GN=GSTT1","GSTT1",27.335,62.029,17.1,3,5,3,1.392,1.308,1.59,0.545,0.602,0.617,0.411,0.000215,"cytoplasm\r","GO:0006790 sulfur compound metabolic process; GO:0006518 peptide metabolic process; GO:0044711 single-organism biosynthetic process; GO:0009636 response to toxic substance; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0006807 nitrogen compound metabolic process; GO:0009058 biosynthetic process; GO:0043603 cellular amide metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:1901576 organic substance biosynthetic process; GO:0044237 cellular metabolic process; GO:0044272 sulfur compound biosynthetic process; GO:0044249 cellular biosynthetic process; GO:1901687 glutathione derivative biosynthetic process; GO:0071704 organic substance metabolic process; GO:1901685 glutathione derivative metabolic process; GO:0008152 metabolic process; GO:0042221 response to chemical; GO:1990748 cellular detoxification; GO:0006575 cellular modified amino acid metabolic process; GO:0044710 single-organism metabolic process; GO:0006749 glutathione metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0098869 cellular oxidant detoxification; GO:0098754 detoxification; GO:0009987 cellular process; GO:1901564 organonitrogen compound metabolic process; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0004364 glutathione transferase activity; GO:0004602 glutathione peroxidase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups; GO:0016209 antioxidant activity; GO:0005515 protein binding; GO:0004601 peroxidase activity; GO:0016740 transferase activity; GO:0016684 oxidoreductase activity, acting on peroxide as acceptor; GO:0016491 oxidoreductase activity; ","K00799","GST; glutathione S-transferase [EC:2.5.1.18]","hsa01524 Platinum drug resistance - Homo sapiens (human); hsa00480 Glutathione metabolism - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa05204 Chemical carcinogenesis - Homo sapiens (human); hsa00980 Metabolism of xenobiotics by cytochrome P450 - Homo sapiens (human); hsa05225 Hepatocellular carcinoma - Homo sapiens (human); hsa00983 Drug metabolism - other enzymes - Homo sapiens (human); hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human); hsa00982 Drug metabolism - cytochrome P450 - Homo sapiens (human); hsa05215 Prostate cancer - Homo sapiens (human); ","IPR004046; IPR010987; IPR012336; IPR004045; ","\"Glutathione S-transferase, C-terminal; Glutathione S-transferase, C-terminal-like; Thioredoxin-like fold; Glutathione S-transferase, N-terminal; \"\r"]
["P30825","High affinity cationic amino acid transporter 1 OS=Homo sapiens OX=9606 GN=SLC7A1","SLC7A1",67.638,13.7,6.7,3,3,3,0.598,0.637,0.597,1.333,1.388,1.404,2.252,3.39e-06,"plasma membrane\r","GO:0034220 ion transmembrane transport; GO:0098655 cation transmembrane transport; GO:0044699 single-organism process; GO:0071702 organic substance transport; GO:0003333 amino acid transmembrane transport; GO:0046942 carboxylic acid transport; GO:0015849 organic acid transport; GO:0098656 anion transmembrane transport; GO:0051234 establishment of localization; GO:0006810 transport; GO:0006820 anion transport; GO:0015802 basic amino acid transport; GO:0055085 transmembrane transport; GO:0015711 organic anion transport; GO:1902578 single-organism localization; GO:1903825 organic acid transmembrane transport; GO:0006812 cation transport; GO:0006811 ion transport; GO:0015809 arginine transport; GO:0006865 amino acid transport; GO:1903826 arginine transmembrane transport; GO:0051179 localization; GO:0071705 nitrogen compound transport; GO:1905039 carboxylic acid transmembrane transport; GO:0044765 single-organism transport; ","GO:0016020 membrane; GO:0031226 intrinsic component of plasma membrane; GO:0044459 plasma membrane part; GO:0044425 membrane part; GO:0044464 cell part; GO:0071944 cell periphery; GO:0031224 intrinsic component of membrane; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; ","GO:0005342 organic acid transmembrane transporter activity; GO:0015075 ion transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0015181 arginine transmembrane transporter activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0015174 basic amino acid transmembrane transporter activity; GO:0005488 binding; GO:0008514 organic anion transmembrane transporter activity; GO:0008324 cation transmembrane transporter activity; GO:0008509 anion transmembrane transporter activity; GO:0015171 amino acid transmembrane transporter activity; GO:0046943 carboxylic acid transmembrane transporter activity; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; ","K13863","SLC7A1; solute carrier family 7 (cationic amino acid transporter), member 1","hsa05206 MicroRNAs in cancer - Homo sapiens (human); ","IPR029485; ","\"Cationic amino acid transporter, C-terminal; \"\r"]
["P30876","DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B","POLR2B",133.9,7.1113,1.7,2,2,2,1.099,1.096,1.013,1.048,0.838,0.93,0.878,0.128,"cytoplasm\r","GO:0044700 single organism signaling; GO:0007166 cell surface receptor signaling pathway; GO:0097659 nucleic acid-templated transcription; GO:0006289 nucleotide-excision repair; GO:0009891 positive regulation of biosynthetic process; GO:0006354 DNA-templated transcription, elongation; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0009719 response to endogenous stimulus; GO:0070848 response to growth factor; GO:0043170 macromolecule metabolic process; GO:0006396 RNA processing; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0050434 positive regulation of viral transcription; GO:0031047 gene silencing by RNA; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0044707 single-multicellular organism process; GO:0006283 transcription-coupled nucleotide-excision repair; GO:0035019 somatic stem cell population maintenance; GO:0006259 DNA metabolic process; GO:0048519 negative regulation of biological process; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0098781 ncRNA transcription; GO:0000375 RNA splicing, via transesterification reactions; GO:0071774 response to fibroblast growth factor; GO:0016073 snRNA metabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0008380 RNA splicing; GO:0051254 positive regulation of RNA metabolic process; GO:0006370 7-methylguanosine mRNA capping; GO:0006950 response to stress; GO:0043900 regulation of multi-organism process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006368 transcription elongation from RNA polymerase II promoter; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0006974 cellular response to DNA damage stimulus; GO:0046782 regulation of viral transcription; GO:0031325 positive regulation of cellular metabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0042795 snRNA transcription from RNA polymerase II promoter; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0071363 cellular response to growth factor stimulus; GO:0008543 fibroblast growth factor receptor signaling pathway; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0070887 cellular response to chemical stimulus; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0032502 developmental process; GO:1903902 positive regulation of viral life cycle; GO:0010468 regulation of gene expression; GO:0036260 RNA capping; GO:0043902 positive regulation of multi-organism process; GO:0031326 regulation of cellular biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:0009301 snRNA transcription; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0098727 maintenance of cell number; GO:0019222 regulation of metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0006352 DNA-templated transcription, initiation; GO:0009452 7-methylguanosine RNA capping; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0019827 stem cell population maintenance; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006367 transcription initiation from RNA polymerase II promoter; GO:0010629 negative regulation of gene expression; GO:0050792 regulation of viral process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0006281 DNA repair; GO:0016458 gene silencing; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0048524 positive regulation of viral process; GO:0044767 single-organism developmental process; GO:0071495 cellular response to endogenous stimulus; GO:0006366 transcription from RNA polymerase II promoter; GO:0044344 cellular response to fibroblast growth factor stimulus; GO:0010467 gene expression; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:1903900 regulation of viral life cycle; GO:0034660 ncRNA metabolic process; GO:0065007 biological regulation; ","GO:0005665 DNA-directed RNA polymerase II, core complex; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0000428 DNA-directed RNA polymerase complex; GO:0055029 nuclear DNA-directed RNA polymerase complex; GO:0061695 transferase complex, transferring phosphorus-containing groups; GO:0044446 intracellular organelle part; GO:0030880 RNA polymerase complex; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:1990234 transferase complex; GO:0005623 cell; GO:0044422 organelle part; GO:0016591 DNA-directed RNA polymerase II, holoenzyme; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0003677 DNA binding; GO:0003723 RNA binding; GO:0034062 5'-3' RNA polymerase activity; GO:0097747 RNA polymerase activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0005515 protein binding; GO:0003682 chromatin binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016779 nucleotidyltransferase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0003899 DNA-directed 5'-3' RNA polymerase activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0016740 transferase activity; GO:0036094 small molecule binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K03010","RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]","hsa00230 Purine metabolism - Homo sapiens (human); hsa03020 RNA polymerase - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa00240 Pyrimidine metabolism - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR007645; IPR007120; IPR007641; IPR014724; IPR007642; IPR007644; IPR007646; IPR007647; ","\"RNA polymerase Rpb2, domain 3; DNA-directed RNA polymerase, subunit 2, domain 6; RNA polymerase Rpb2, domain 7; RNA polymerase Rpb2, OB-fold; RNA polymerase Rpb2, domain 2; RNA polymerase, beta subunit, protrusion; RNA polymerase Rpb2, domain 4; RNA polymerase Rpb2, domain 5; \"\r"]
["P31150","Rab GDP dissociation inhibitor alpha OS=Homo sapiens OX=9606 GN=GDI1","GDI1",50.582,65.222,47.9,18,30,10,1.094,1.07,1.105,0.923,0.939,0.891,0.842,0.000695,"endoplasmic reticulum\r","GO:0044700 single organism signaling; GO:0051093 negative regulation of developmental process; GO:1903533 regulation of protein targeting; GO:0023051 regulation of signaling; GO:0051129 negative regulation of cellular component organization; GO:0048869 cellular developmental process; GO:0090317 negative regulation of intracellular protein transport; GO:0022008 neurogenesis; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0010035 response to inorganic substance; GO:0032387 negative regulation of intracellular transport; GO:0050771 negative regulation of axonogenesis; GO:0045596 negative regulation of cell differentiation; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0051056 regulation of small GTPase mediated signal transduction; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0051051 negative regulation of transport; GO:1905476 negative regulation of protein localization to membrane; GO:0051716 cellular response to stimulus; GO:1903828 negative regulation of cellular protein localization; GO:0048699 generation of neurons; GO:0055114 oxidation-reduction process; GO:0044763 single-organism cellular process; GO:0032386 regulation of intracellular transport; GO:0007264 small GTPase mediated signal transduction; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0010038 response to metal ion; GO:0050768 negative regulation of neurogenesis; GO:0006810 transport; GO:0042221 response to chemical; GO:0090315 negative regulation of protein targeting to membrane; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:0045664 regulation of neuron differentiation; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0045665 negative regulation of neuron differentiation; GO:0065009 regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0051223 regulation of protein transport; GO:0010721 negative regulation of cell development; GO:0048856 anatomical structure development; GO:0010975 regulation of neuron projection development; GO:0007265 Ras protein signal transduction; GO:2000026 regulation of multicellular organismal development; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0031344 regulation of cell projection organization; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:0070201 regulation of establishment of protein localization; GO:0060341 regulation of cellular localization; GO:0030154 cell differentiation; GO:1905475 regulation of protein localization to membrane; GO:0051961 negative regulation of nervous system development; GO:0051345 positive regulation of hydrolase activity; GO:0031345 negative regulation of cell projection organization; GO:0051592 response to calcium ion; GO:0007275 multicellular organism development; GO:0032880 regulation of protein localization; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:0033157 regulation of intracellular protein transport; GO:0045595 regulation of cell differentiation; GO:0010771 negative regulation of cell morphogenesis involved in differentiation; GO:1902531 regulation of intracellular signal transduction; GO:0035556 intracellular signal transduction; GO:0043547 positive regulation of GTPase activity; GO:0051224 negative regulation of protein transport; GO:0048731 system development; GO:0051049 regulation of transport; GO:0051960 regulation of nervous system development; GO:0060284 regulation of cell development; GO:0010977 negative regulation of neuron projection development; GO:0071702 organic substance transport; GO:0032482 Rab protein signal transduction; GO:0050770 regulation of axonogenesis; GO:0043085 positive regulation of catalytic activity; GO:0045184 establishment of protein localization; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0061024 membrane organization; GO:1904950 negative regulation of establishment of protein localization; GO:0051128 regulation of cellular component organization; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0022604 regulation of cell morphogenesis; GO:0090313 regulation of protein targeting to membrane; GO:1903827 regulation of cellular protein localization; GO:0050767 regulation of neurogenesis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0005737 cytoplasm; GO:0030496 midbody; GO:0032991 macromolecular complex; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005622 intracellular; GO:0044464 cell part; GO:0043209 myelin sheath; GO:0043005 neuron projection; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0005794 Golgi apparatus; GO:0097458 neuron part; GO:0044444 cytoplasmic part; ","GO:0031267 small GTPase binding; GO:0005092 GDP-dissociation inhibitor activity; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0030695 GTPase regulator activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0017137 Rab GTPase binding; GO:0016491 oxidoreductase activity; GO:0030234 enzyme regulator activity; GO:0017016 Ras GTPase binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0005093 Rab GDP-dissociation inhibitor activity; GO:0051020 GTPase binding; GO:0008047 enzyme activator activity; GO:0019899 enzyme binding; GO:0005096 GTPase activator activity; ","K17255",null,null,"IPR023753; ","FAD/NAD(P)-binding domain; \r"]
["P31153","S-adenosylmethionine synthase isoform type-2 OS=Homo sapiens OX=9606 GN=MAT2A","MAT2A",43.66,53.53,28.4,9,13,9,1.022,1.029,0.951,1.005,0.972,1.008,0.994,0.861,"cytoplasm\r","GO:0051188 cofactor biosynthetic process; GO:0044085 cellular component biogenesis; GO:0016043 cellular component organization; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0032259 methylation; GO:0044272 sulfur compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0051259 protein oligomerization; GO:0008152 metabolic process; GO:0006730 one-carbon metabolic process; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0009108 coenzyme biosynthetic process; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0006790 sulfur compound metabolic process; GO:0071822 protein complex subunit organization; GO:0046500 S-adenosylmethionine metabolic process; GO:0034214 protein hexamerization; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006732 coenzyme metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0051186 cofactor metabolic process; GO:0051291 protein heterooligomerization; GO:0044710 single-organism metabolic process; GO:0070271 protein complex biogenesis; GO:0006556 S-adenosylmethionine biosynthetic process; GO:0071840 cellular component organization or biogenesis; ","GO:1902494 catalytic complex; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0048269 methionine adenosyltransferase complex; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:1990234 transferase complex; GO:0005623 cell; GO:0005829 cytosol; GO:0044444 cytoplasmic part; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0004478 methionine adenosyltransferase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K00789","metK; S-adenosylmethionine synthetase [EC:2.5.1.6]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00270 Cysteine and methionine metabolism - Homo sapiens (human); hsa01230 Biosynthesis of amino acids - Homo sapiens (human); ","IPR022636; IPR022628; IPR022629; IPR022630; ","\"S-adenosylmethionine synthetase superfamily; S-adenosylmethionine synthetase, N-terminal; S-adenosylmethionine synthetase, central domain; S-adenosylmethionine synthetase, C-terminal; \"\r"]
["P31323","cAMP-dependent protein kinase type II-beta regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2B","PRKAR2B",46.302,33.52,29.7,10,11,8,1.128,1.067,1.26,0.865,0.883,0.773,0.73,0.00798,"cytoplasm\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0097332 response to antipsychotic drug; GO:0060271 cilium assembly; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0050877 neurological system process; GO:0044782 cilium organization; GO:0007610 behavior; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0008152 metabolic process; GO:0044093 positive regulation of molecular function; GO:0032787 monocarboxylic acid metabolic process; GO:0009719 response to endogenous stimulus; GO:0044770 cell cycle phase transition; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0051347 positive regulation of transferase activity; GO:1901652 response to peptide; GO:0000278 mitotic cell cycle; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0010243 response to organonitrogen compound; GO:0030104 water homeostasis; GO:0007612 learning; GO:0032269 negative regulation of cellular protein metabolic process; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:1901698 response to nitrogen compound; GO:0010604 positive regulation of macromolecule metabolic process; GO:0050817 coagulation; GO:0000086 G2/M transition of mitotic cell cycle; GO:0044708 single-organism behavior; GO:0043436 oxoacid metabolic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0031399 regulation of protein modification process; GO:1901700 response to oxygen-containing compound; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:1903047 mitotic cell cycle process; GO:0042493 response to drug; GO:0032147 activation of protein kinase activity; GO:0051338 regulation of transferase activity; GO:0001933 negative regulation of protein phosphorylation; GO:0034199 activation of protein kinase A activity; GO:0048878 chemical homeostasis; GO:0044772 mitotic cell cycle phase transition; GO:0006950 response to stress; GO:0003014 renal system process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0030031 cell projection assembly; GO:0051247 positive regulation of protein metabolic process; GO:0050891 multicellular organismal water homeostasis; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0044839 cell cycle G2/M phase transition; GO:0033762 response to glucagon; GO:0045936 negative regulation of phosphate metabolic process; GO:0044699 single-organism process; GO:0048871 multicellular organismal homeostasis; GO:0031400 negative regulation of protein modification process; GO:0009611 response to wounding; GO:0007165 signal transduction; GO:1901653 cellular response to peptide; GO:0007154 cell communication; GO:0071901 negative regulation of protein serine/threonine kinase activity; GO:0022607 cellular component assembly; GO:0009893 positive regulation of metabolic process; GO:0033673 negative regulation of kinase activity; GO:0033674 positive regulation of kinase activity; GO:0070887 cellular response to chemical stimulus; GO:0097338 response to clozapine; GO:0003091 renal water homeostasis; GO:0006629 lipid metabolic process; GO:0045937 positive regulation of phosphate metabolic process; GO:0048522 positive regulation of cellular process; GO:0051348 negative regulation of transferase activity; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0071417 cellular response to organonitrogen compound; GO:2000480 negative regulation of cAMP-dependent protein kinase activity; GO:1902589 single-organism organelle organization; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0043434 response to peptide hormone; GO:0030030 cell projection organization; GO:1901699 cellular response to nitrogen compound; GO:0032870 cellular response to hormone stimulus; GO:0006469 negative regulation of protein kinase activity; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0006082 organic acid metabolic process; GO:0043549 regulation of kinase activity; GO:0045859 regulation of protein kinase activity; GO:0016043 cellular component organization; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0097711 ciliary basal body docking; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0022406 membrane docking; GO:0007599 hemostasis; GO:0071704 organic substance metabolic process; GO:0071377 cellular response to glucagon stimulus; GO:0042592 homeostatic process; GO:0070925 organelle assembly; GO:0042326 negative regulation of phosphorylation; GO:0071375 cellular response to peptide hormone stimulus; GO:0050890 cognition; GO:0009987 cellular process; GO:0050878 regulation of body fluid levels; GO:0003008 system process; GO:0035556 intracellular signal transduction; GO:0001932 regulation of protein phosphorylation; GO:0031401 positive regulation of protein modification process; GO:0006631 fatty acid metabolic process; GO:0001934 positive regulation of protein phosphorylation; GO:0045860 positive regulation of protein kinase activity; GO:0048518 positive regulation of biological process; GO:0007611 learning or memory; GO:0043085 positive regulation of catalytic activity; GO:1901701 cellular response to oxygen-containing compound; GO:0042060 wound healing; GO:2000479 regulation of cAMP-dependent protein kinase activity; GO:0071495 cellular response to endogenous stimulus; GO:0051246 regulation of protein metabolic process; GO:0010563 negative regulation of phosphorus metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0022402 cell cycle process; GO:0009725 response to hormone; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0030425 dendrite; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0098857 membrane microdomain; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0043025 neuronal cell body; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043197 dendritic spine; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0005740 mitochondrial envelope; GO:0070062 extracellular exosome; GO:0005815 microtubule organizing center; GO:0044309 neuron spine; GO:0015630 microtubule cytoskeleton; GO:0044441 ciliary part; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0098805 whole membrane; GO:0019866 organelle inner membrane; GO:0098589 membrane region; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0043005 neuron projection; GO:0045121 membrane raft; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0097458 neuron part; GO:0044456 synapse part; GO:0097546 ciliary base; GO:0005929 cilium; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0044429 mitochondrial part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0045202 synapse; GO:0005952 cAMP-dependent protein kinase complex; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0098794 postsynapse; GO:0005813 centrosome; GO:0031975 envelope; GO:0043198 dendritic shaft; GO:0044297 cell body; GO:0031966 mitochondrial membrane; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0030291 protein serine/threonine kinase inhibitor activity; GO:0051018 protein kinase A binding; GO:1901265 nucleoside phosphate binding; GO:0031625 ubiquitin protein ligase binding; GO:0019901 protein kinase binding; GO:0004860 protein kinase inhibitor activity; GO:0005515 protein binding; GO:0019207 kinase regulator activity; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0008603 cAMP-dependent protein kinase regulator activity; GO:0004862 cAMP-dependent protein kinase inhibitor activity; GO:0017076 purine nucleotide binding; GO:0030552 cAMP binding; GO:0030551 cyclic nucleotide binding; GO:0043167 ion binding; GO:0019887 protein kinase regulator activity; GO:0000166 nucleotide binding; GO:0019900 kinase binding; GO:0097367 carbohydrate derivative binding; GO:0030234 enzyme regulator activity; GO:0019210 kinase inhibitor activity; GO:0019904 protein domain specific binding; GO:0032555 purine ribonucleotide binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0034236 protein kinase A catalytic subunit binding; GO:0019899 enzyme binding; GO:0036094 small molecule binding; ","K04739","PRKAR; cAMP-dependent protein kinase regulator","hsa04910 Insulin signaling pathway - Homo sapiens (human); ","IPR000595; IPR018490; IPR003117; IPR014710; ","\"Cyclic nucleotide-binding domain; Cyclic nucleotide-binding-like; cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain; RmlC-like jelly roll fold; \"\r"]
["P31930","Cytochrome b-c1 complex subunit 1, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC1","UQCRC1",52.645,122.78,34,12,27,11,0.885,0.911,1.1,1.114,1.022,1.036,1.095,0.264,"mitochondria\r","GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0016485 protein processing; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0006753 nucleoside phosphate metabolic process; GO:0009719 response to endogenous stimulus; GO:0019693 ribose phosphate metabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044765 single-organism transport; GO:0098655 cation transmembrane transport; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0006119 oxidative phosphorylation; GO:0044763 single-organism cellular process; GO:0072521 purine-containing compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0006810 transport; GO:0010243 response to organonitrogen compound; GO:0014823 response to activity; GO:0042221 response to chemical; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:1901698 response to nitrogen compound; GO:0022900 electron transport chain; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0098662 inorganic cation transmembrane transport; GO:0016310 phosphorylation; GO:0034220 ion transmembrane transport; GO:0006725 cellular aromatic compound metabolic process; GO:0042773 ATP synthesis coupled electron transport; GO:0009259 ribonucleotide metabolic process; GO:0043279 response to alkaloid; GO:0022904 respiratory electron transport chain; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0006812 cation transport; GO:0006139 nucleobase-containing compound metabolic process; GO:1902600 hydrogen ion transmembrane transport; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0006508 proteolysis; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009119 ribonucleoside metabolic process; GO:0009987 cellular process; GO:0046034 ATP metabolic process; GO:0098660 inorganic ion transmembrane transport; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0045333 cellular respiration; GO:0015992 proton transport; GO:0006818 hydrogen transport; GO:0006163 purine nucleotide metabolic process; GO:0055085 transmembrane transport; GO:0046128 purine ribonucleoside metabolic process; GO:0006793 phosphorus metabolic process; GO:0006811 ion transport; GO:0009060 aerobic respiration; GO:0019637 organophosphate metabolic process; GO:0010467 gene expression; GO:0009150 purine ribonucleotide metabolic process; GO:0051179 localization; GO:0051604 protein maturation; GO:0015672 monovalent inorganic cation transport; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:1902494 catalytic complex; GO:0005750 mitochondrial respiratory chain complex III; GO:0043209 myelin sheath; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0019866 organelle inner membrane; GO:1990351 transporter complex; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0098803 respiratory chain complex; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0070069 cytochrome complex; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:1902495 transmembrane transporter complex; GO:0005829 cytosol; GO:0016021 integral component of membrane; GO:0045275 respiratory chain complex III; GO:0005739 mitochondrion; GO:0005746 mitochondrial respiratory chain; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:1990204 oxidoreductase complex; GO:0031975 envelope; GO:0043234 protein complex; GO:0070469 respiratory chain; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0008233 peptidase activity; GO:0031625 ubiquitin protein ligase binding; GO:0022892 substrate-specific transporter activity; GO:0015077 monovalent inorganic cation transmembrane transporter activity; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0015078 hydrogen ion transmembrane transporter activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043169 cation binding; GO:0022890 inorganic cation transmembrane transporter activity; GO:0005215 transporter activity; GO:0004222 metalloendopeptidase activity; GO:0016679 oxidoreductase activity, acting on diphenols and related substances as donors; GO:0015075 ion transmembrane transporter activity; GO:0008121 ubiquinol-cytochrome-c reductase activity; GO:0043167 ion binding; GO:0044877 macromolecular complex binding; GO:0008237 metallopeptidase activity; GO:0008270 zinc ion binding; GO:0016681 oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor; GO:0016491 oxidoreductase activity; GO:0004175 endopeptidase activity; GO:0046914 transition metal ion binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0046872 metal ion binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0019899 enzyme binding; GO:0008324 cation transmembrane transporter activity; GO:0032403 protein complex binding; GO:0022857 transmembrane transporter activity; ","K00414","QCR1; ubiquinol-cytochrome c reductase core subunit 1","hsa04260 Cardiac muscle contraction - Homo sapiens (human); hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); ","IPR007863; IPR011765; IPR011249; IPR011237; ","\"Peptidase M16, C-terminal; Peptidase M16, N-terminal; Metalloenzyme, LuxS/M16 peptidase-like; Peptidase M16 domain; \"\r"]
["P31937","3-hydroxyisobutyrate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=HIBADH","HIBADH",35.329,42.445,24.1,6,7,6,1.111,1.127,1.05,0.856,0.988,0.872,0.826,0.0182,"mitochondria\r","GO:1901606 alpha-amino acid catabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006573 valine metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0044248 cellular catabolic process; GO:0009081 branched-chain amino acid metabolic process; GO:0009987 cellular process; GO:0044712 single-organism catabolic process; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006574 valine catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044282 small molecule catabolic process; GO:0044238 primary metabolic process; GO:1901605 alpha-amino acid metabolic process; GO:0046395 carboxylic acid catabolic process; GO:0009083 branched-chain amino acid catabolic process; GO:1901575 organic substance catabolic process; GO:1901565 organonitrogen compound catabolic process; GO:0044710 single-organism metabolic process; GO:0016054 organic acid catabolic process; GO:0019752 carboxylic acid metabolic process; GO:0009063 cellular amino acid catabolic process; GO:0006082 organic acid metabolic process; GO:0009056 catabolic process; GO:0043436 oxoacid metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:1901265 nucleoside phosphate binding; GO:0000166 nucleotide binding; GO:0048037 cofactor binding; GO:0016491 oxidoreductase activity; GO:0016614 oxidoreductase activity, acting on CH-OH group of donors; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity; GO:0008442 3-hydroxyisobutyrate dehydrogenase activity; GO:0003824 catalytic activity; GO:0051287 NAD binding; GO:0005488 binding; GO:0050662 coenzyme binding; GO:0036094 small molecule binding; ","K00020","mmsB; 3-hydroxyisobutyrate dehydrogenase [EC:1.1.1.31]","hsa00280 Valine, leucine and isoleucine degradation - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR006115; IPR013328; IPR008927; IPR016040; IPR029154; ","\"6-phosphogluconate dehydrogenase, NADP-binding; 6-phosphogluconate dehydrogenase, domain 2; 6-phosphogluconate dehydrogenase C-terminal domain-like; NAD(P)-binding domain; 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain; \"\r"]
["P31943","Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1","HNRNPH1",49.229,203.09,35,13,26,5,0.945,0.931,0.916,1.055,1.079,1.063,1.145,0.000262,"nucleus\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0006725 cellular aromatic compound metabolic process; GO:0007166 cell surface receptor signaling pathway; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0071310 cellular response to organic substance; GO:0044699 single-organism process; GO:0071363 cellular response to growth factor stimulus; GO:0050896 response to stimulus; GO:0008543 fibroblast growth factor receptor signaling pathway; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0007154 cell communication; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0071774 response to fibroblast growth factor; GO:0051171 regulation of nitrogen compound metabolic process; GO:0009719 response to endogenous stimulus; GO:0070848 response to growth factor; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0070887 cellular response to chemical stimulus; GO:0006396 RNA processing; GO:0010468 regulation of gene expression; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0010033 response to organic substance; GO:0031323 regulation of cellular metabolic process; GO:0044238 primary metabolic process; GO:0023052 signaling; GO:0051252 regulation of RNA metabolic process; GO:0006397 mRNA processing; GO:0043484 regulation of RNA splicing; GO:0016070 RNA metabolic process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0071495 cellular response to endogenous stimulus; GO:0044344 cellular response to fibroblast growth factor stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0010467 gene expression; GO:0016071 mRNA metabolic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005681 spliceosomal complex; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0071013 catalytic step 2 spliceosome; GO:1990904 ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0030529 intracellular ribonucleoprotein complex; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0008187 poly-pyrimidine tract binding; GO:1901265 nucleoside phosphate binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0008266 poly(U) RNA binding; GO:0000166 nucleotide binding; GO:0003727 single-stranded RNA binding; GO:0036094 small molecule binding; ","K12898",null,null,"IPR000504; IPR012677; IPR012996; ","\"RNA recognition motif domain; Nucleotide-binding alpha-beta plait domain; Zinc finger, CHHC-type; \"\r"]
["P31946","14-3-3 protein beta/alpha OS=Homo sapiens OX=9606 GN=YWHAB","YWHAB",28.082,166.85,45.5,10,46,5,0.95,0.969,0.977,1.018,1.028,1.06,1.073,0.00902,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0010941 regulation of cell death; GO:0010608 posttranscriptional regulation of gene expression; GO:0044237 cellular metabolic process; GO:0010821 regulation of mitochondrion organization; GO:0015031 protein transport; GO:0008152 metabolic process; GO:1901028 regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; GO:0065003 macromolecular complex assembly; GO:0032879 regulation of localization; GO:1903747 regulation of establishment of protein localization to mitochondrion; GO:0044093 positive regulation of molecular function; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0090559 regulation of membrane permeability; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0051651 maintenance of location in cell; GO:0044419 interspecies interaction between organisms; GO:0008104 protein localization; GO:0051220 cytoplasmic sequestering of protein; GO:0051716 cellular response to stimulus; GO:0035305 negative regulation of dephosphorylation; GO:0035329 hippo signaling; GO:0051174 regulation of phosphorus metabolic process; GO:0032507 maintenance of protein location in cell; GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0031323 regulation of cellular metabolic process; GO:0051704 multi-organism process; GO:0051291 protein heterooligomerization; GO:0006810 transport; GO:0000165 MAPK cascade; GO:1903506 regulation of nucleic acid-templated transcription; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0035304 regulation of protein dephosphorylation; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0043068 positive regulation of programmed cell death; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016310 phosphorylation; GO:0046907 intracellular transport; GO:0007006 mitochondrial membrane organization; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0043067 regulation of programmed cell death; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:1905477 positive regulation of protein localization to membrane; GO:0051259 protein oligomerization; GO:0043487 regulation of RNA stability; GO:0060341 regulation of cellular localization; GO:0045892 negative regulation of transcription, DNA-templated; GO:1900740 positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:1902578 single-organism localization; GO:0009889 regulation of biosynthetic process; GO:0035308 negative regulation of protein dephosphorylation; GO:0051171 regulation of nitrogen compound metabolic process; GO:1901030 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; GO:0032880 regulation of protein localization; GO:0034613 cellular protein localization; GO:0009966 regulation of signal transduction; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0006461 protein complex assembly; GO:0023014 signal transduction by protein phosphorylation; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0045184 establishment of protein localization; GO:0009890 negative regulation of biosynthetic process; GO:1904951 positive regulation of establishment of protein localization; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; GO:0043412 macromolecule modification; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0045936 negative regulation of phosphate metabolic process; GO:1903827 regulation of cellular protein localization; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0006839 mitochondrial transport; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0051253 negative regulation of RNA metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:1903749 positive regulation of establishment of protein localization to mitochondrion; GO:0031400 negative regulation of protein modification process; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0051130 positive regulation of cellular component organization; GO:2001141 regulation of RNA biosynthetic process; GO:2001233 regulation of apoptotic signaling pathway; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0007005 mitochondrion organization; GO:0035303 regulation of dephosphorylation; GO:0033036 macromolecule localization; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0010468 regulation of gene expression; GO:0071822 protein complex subunit organization; GO:0031326 regulation of cellular biosynthetic process; GO:0008277 regulation of G-protein coupled receptor protein signaling pathway; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0010942 positive regulation of cell death; GO:0051050 positive regulation of transport; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0010638 positive regulation of organelle organization; GO:1902679 negative regulation of RNA biosynthetic process; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0036211 protein modification process; GO:0070271 protein complex biogenesis; GO:0016043 cellular component organization; GO:1903829 positive regulation of cellular protein localization; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0043065 positive regulation of apoptotic process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0070201 regulation of establishment of protein localization; GO:0071704 organic substance metabolic process; GO:1905475 regulation of protein localization to membrane; GO:0006468 protein phosphorylation; GO:0046902 regulation of mitochondrial membrane permeability; GO:0023056 positive regulation of signaling; GO:0016032 viral process; GO:0006886 intracellular protein transport; GO:2001235 positive regulation of apoptotic signaling pathway; GO:0051235 maintenance of location; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:0006355 regulation of transcription, DNA-templated; GO:0045185 maintenance of protein location; GO:0035556 intracellular signal transduction; GO:0010629 negative regulation of gene expression; GO:0051049 regulation of transport; GO:0033043 regulation of organelle organization; GO:0044802 single-organism membrane organization; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0043488 regulation of mRNA stability; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0043933 macromolecular complex subunit organization; GO:0043085 positive regulation of catalytic activity; GO:0051641 cellular localization; GO:0010822 positive regulation of mitochondrion organization; GO:0070727 cellular macromolecule localization; GO:0051246 regulation of protein metabolic process; GO:0010563 negative regulation of phosphorus metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0009967 positive regulation of signal transduction; GO:0051128 regulation of cellular component organization; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0017053 transcriptional repressor complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0048770 pigment granule; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0042470 melanosome; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0012506 vesicle membrane; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0003714 transcription corepressor activity; GO:0016597 amino acid binding; GO:0050815 phosphoserine binding; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0043177 organic acid binding; GO:0005515 protein binding; GO:0045309 protein phosphorylated amino acid binding; GO:0003712 transcription cofactor activity; GO:0051219 phosphoprotein binding; GO:0050839 cell adhesion molecule binding; GO:0031406 carboxylic acid binding; GO:0042826 histone deacetylase binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0019904 protein domain specific binding; GO:0008022 protein C-terminus binding; GO:0043168 anion binding; GO:0000988 transcription factor activity, protein binding; GO:0019899 enzyme binding; GO:0032403 protein complex binding; GO:0036094 small molecule binding; ","K16197","YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta","hsa04390 Hippo signaling pathway - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa04110 Cell cycle - Homo sapiens (human); hsa05161 Hepatitis B - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human); hsa04114 Oocyte meiosis - Homo sapiens (human); hsa05203 Viral carcinogenesis - Homo sapiens (human); ","IPR023410; ","14-3-3 domain; \r"]
["P32119","Peroxiredoxin-2 OS=Homo sapiens OX=9606 GN=PRDX2","PRDX2",21.892,124.49,56.6,10,30,9,0.971,0.993,0.988,1.009,1.01,1.022,1.03,0.02,"cytoplasm\r","GO:0006801 superoxide metabolic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0010941 regulation of cell death; GO:0000303 response to superoxide; GO:0065008 regulation of biological quality; GO:0043069 negative regulation of programmed cell death; GO:0045454 cell redox homeostasis; GO:0043067 regulation of programmed cell death; GO:1901700 response to oxygen-containing compound; GO:0044699 single-organism process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0019430 removal of superoxide radicals; GO:0042592 homeostatic process; GO:0008152 metabolic process; GO:0042743 hydrogen peroxide metabolic process; GO:1990748 cellular detoxification; GO:0043066 negative regulation of apoptotic process; GO:0072593 reactive oxygen species metabolic process; GO:0006979 response to oxidative stress; GO:0044248 cellular catabolic process; GO:0098869 cellular oxidant detoxification; GO:0010035 response to inorganic substance; GO:0034599 cellular response to oxidative stress; GO:0042744 hydrogen peroxide catabolic process; GO:0009987 cellular process; GO:0070887 cellular response to chemical stimulus; GO:0051716 cellular response to stimulus; GO:0034614 cellular response to reactive oxygen species; GO:0006950 response to stress; GO:0071450 cellular response to oxygen radical; GO:0071451 cellular response to superoxide; GO:0055114 oxidation-reduction process; GO:0000302 response to reactive oxygen species; GO:0009636 response to toxic substance; GO:0044763 single-organism cellular process; GO:0019725 cellular homeostasis; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:1901701 cellular response to oxygen-containing compound; GO:0044710 single-organism metabolic process; GO:0000305 response to oxygen radical; GO:0009056 catabolic process; GO:0060548 negative regulation of cell death; GO:0098754 detoxification; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0003824 catalytic activity; GO:0008379 thioredoxin peroxidase activity; GO:0051920 peroxiredoxin activity; GO:0016209 antioxidant activity; GO:0004601 peroxidase activity; GO:0016491 oxidoreductase activity; GO:0016684 oxidoreductase activity, acting on peroxide as acceptor; ","K03386",null,null,"IPR019479; IPR000866; IPR012336; IPR013766; ","\"Peroxiredoxin, C-terminal; Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant; Thioredoxin-like fold; Thioredoxin domain; \"\r"]
["P32320","Cytidine deaminase OS=Homo sapiens OX=9606 GN=CDA","CDA",16.185,15.901,19.9,2,2,2,1.071,1.078,1.044,0.958,0.883,0.985,0.885,0.0229,"extracellular\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0009116 nucleoside metabolic process; GO:0045321 leukocyte activation; GO:0007166 cell surface receptor signaling pathway; GO:0045980 negative regulation of nucleotide metabolic process; GO:0009163 nucleoside biosynthetic process; GO:0043174 nucleoside salvage; GO:0044237 cellular metabolic process; GO:0001558 regulation of cell growth; GO:0008152 metabolic process; GO:0006213 pyrimidine nucleoside metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0065003 macromolecular complex assembly; GO:0072527 pyrimidine-containing compound metabolic process; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0051174 regulation of phosphorus metabolic process; GO:0018130 heterocycle biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0009972 cytidine deamination; GO:0031323 regulation of cellular metabolic process; GO:0006206 pyrimidine nucleobase metabolic process; GO:0046131 pyrimidine ribonucleoside metabolic process; GO:0006810 transport; GO:0019439 aromatic compound catabolic process; GO:1901575 organic substance catabolic process; GO:0072529 pyrimidine-containing compound catabolic process; GO:0046087 cytidine metabolic process; GO:0044710 single-organism metabolic process; GO:0009112 nucleobase metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0006140 regulation of nucleotide metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0050794 regulation of cellular process; GO:0002283 neutrophil activation involved in immune response; GO:0051260 protein homooligomerization; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0051259 protein oligomerization; GO:0044270 cellular nitrogen compound catabolic process; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0044248 cellular catabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0009119 ribonucleoside metabolic process; GO:0006461 protein complex assembly; GO:0044711 single-organism biosynthetic process; GO:0016192 vesicle-mediated transport; GO:1901658 glycosyl compound catabolic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901136 carbohydrate derivative catabolic process; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:0002263 cell activation involved in immune response; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0045055 regulated exocytosis; GO:0001775 cell activation; GO:0051179 localization; GO:0006955 immune response; GO:0009164 nucleoside catabolic process; GO:0045936 negative regulation of phosphate metabolic process; GO:0006887 exocytosis; GO:1901564 organonitrogen compound metabolic process; GO:0046135 pyrimidine nucleoside catabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0051234 establishment of localization; GO:0019858 cytosine metabolic process; GO:0007165 signal transduction; GO:0046134 pyrimidine nucleoside biosynthetic process; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0051262 protein tetramerization; GO:1901361 organic cyclic compound catabolic process; GO:0006216 cytidine catabolic process; GO:0002274 myeloid leukocyte activation; GO:0045926 negative regulation of growth; GO:0071822 protein complex subunit organization; GO:0002446 neutrophil mediated immunity; GO:1901360 organic cyclic compound metabolic process; GO:0023052 signaling; GO:0002444 myeloid leukocyte mediated immunity; GO:0030308 negative regulation of cell growth; GO:0050789 regulation of biological process; GO:0043094 cellular metabolic compound salvage; GO:0032940 secretion by cell; GO:0019222 regulation of metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0043299 leukocyte degranulation; GO:0070271 protein complex biogenesis; GO:0016043 cellular component organization; GO:0040008 regulation of growth; GO:0006725 cellular aromatic compound metabolic process; GO:0002252 immune effector process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0072528 pyrimidine-containing compound biosynthetic process; GO:0042454 ribonucleoside catabolic process; GO:0051289 protein homotetramerization; GO:0034641 cellular nitrogen compound metabolic process; GO:0036230 granulocyte activation; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0043097 pyrimidine nucleoside salvage; GO:0044712 single-organism catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0043312 neutrophil degranulation; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:1901565 organonitrogen compound catabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0008655 pyrimidine-containing compound salvage; GO:1901659 glycosyl compound biosynthetic process; GO:0010563 negative regulation of phosphorus metabolic process; GO:0046133 pyrimidine ribonucleoside catabolic process; GO:0051128 regulation of cellular component organization; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:0046700 heterocycle catabolic process; ","GO:0034774 secretory granule lumen; GO:1904724 tertiary granule lumen; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0070820 tertiary granule; GO:0044433 cytoplasmic vesicle part; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0031983 vesicle lumen; GO:0060205 cytoplasmic vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0046983 protein dimerization activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0008270 zinc ion binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines; GO:0097367 carbohydrate derivative binding; GO:0042802 identical protein binding; GO:0004126 cytidine deaminase activity; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0019239 deaminase activity; GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; GO:0036094 small molecule binding; ","K01489","cdd; cytidine deaminase [EC:3.5.4.5]","hsa00983 Drug metabolism - other enzymes - Homo sapiens (human); hsa00240 Pyrimidine metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR016193; IPR002125; ","\"Cytidine deaminase-like; Cytidine and deoxycytidylate deaminases, zinc-binding; \"\r"]
["P32926","Desmoglein-3 OS=Homo sapiens OX=9606 GN=DSG3","DSG3",107.53,21.837,9.3,8,9,8,0.891,0.867,0.872,1.179,1.138,1.049,1.28,2.3E-3,"plasma membrane\r","GO:0032502 developmental process; GO:0044707 single-multicellular organism process; GO:0060429 epithelium development; GO:0043588 skin development; GO:0030216 keratinocyte differentiation; GO:0009888 tissue development; GO:0031424 keratinization; GO:0048731 system development; GO:0070268 cornification; GO:0048869 cellular developmental process; GO:0098609 cell-cell adhesion; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0032501 multicellular organismal process; GO:0022610 biological adhesion; GO:0009913 epidermal cell differentiation; GO:0048513 animal organ development; GO:0030154 cell differentiation; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0007155 cell adhesion; GO:0008544 epidermis development; GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules; GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules; GO:0012501 programmed cell death; GO:0007275 multicellular organism development; GO:0048856 anatomical structure development; GO:0009987 cellular process; GO:0030855 epithelial cell differentiation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0070161 anchoring junction; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005911 cell-cell junction; GO:0005829 cytosol; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0030057 desmosome; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0001533 cornified envelope; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005509 calcium ion binding; GO:0005488 binding; GO:0043167 ion binding; ","K07598",null,null,"IPR015919; IPR027397; IPR002126; ","Cadherin-like; Catenin binding domain; Cadherin; \r"]
["P32969","60S ribosomal protein L9 OS=Homo sapiens OX=9606 GN=RPL9","RPL9",21.863,39.862,39.6,7,12,7,1.026,0.809,0.884,1.125,1.1,1.055,1.206,0.0556,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0072594 establishment of protein localization to organelle; GO:0006518 peptide metabolic process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0051649 establishment of localization in cell; GO:0002181 cytoplasmic translation; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0070972 protein localization to endoplasmic reticulum; GO:0006364 rRNA processing; GO:0006413 translational initiation; GO:1901361 organic cyclic compound catabolic process; GO:0033365 protein localization to organelle; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0006412 translation; GO:0016072 rRNA metabolic process; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0072657 protein localization to membrane; GO:0043043 peptide biosynthetic process; GO:0042254 ribosome biogenesis; GO:1901360 organic cyclic compound metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032774 RNA biosynthetic process; GO:0045047 protein targeting to ER; GO:0043603 cellular amide metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0006401 RNA catabolic process; GO:0016070 RNA metabolic process; GO:0019439 aromatic compound catabolic process; GO:1901575 organic substance catabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0019083 viral transcription; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0046907 intracellular transport; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0044267 cellular protein metabolic process; GO:0006613 cotranslational protein targeting to membrane; GO:0048519 negative regulation of biological process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0016032 viral process; GO:0019080 viral gene expression; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0006886 intracellular protein transport; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0034613 cellular protein localization; GO:0009059 macromolecule biosynthetic process; GO:0090150 establishment of protein localization to membrane; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0051179 localization; GO:0009056 catabolic process; GO:0034660 ncRNA metabolic process; GO:0071840 cellular component organization or biogenesis; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005925 focal adhesion; GO:0044391 ribosomal subunit; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:0030055 cell-substrate junction; GO:0044445 cytosolic part; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0022626 cytosolic ribosome; GO:0043229 intracellular organelle; GO:0005840 ribosome; GO:0043232 intracellular non-membrane-bounded organelle; GO:0022625 cytosolic large ribosomal subunit; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0031012 extracellular matrix; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0015934 large ribosomal subunit; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0005198 structural molecule activity; GO:0003735 structural constituent of ribosome; GO:0019843 rRNA binding; ","K02940","RP-L9e; large subunit ribosomal protein L9e","hsa03010 Ribosome - Homo sapiens (human); ","IPR020040; ","\"Ribosomal protein L6, alpha-beta domain; \"\r"]
["P33241","Lymphocyte-specific protein 1 OS=Homo sapiens OX=9606 GN=LSP1","LSP1",37.191,20.233,13,4,5,4,0.89,0.87,0.844,0.929,1.194,1.256,1.298,0.0558,"nucleus\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0051716 cellular response to stimulus; GO:0006950 response to stress; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0023052 signaling; GO:0050896 response to stimulus; GO:0006935 chemotaxis; GO:0009605 response to external stimulus; GO:0007165 signal transduction; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0007154 cell communication; GO:0006968 cellular defense response; GO:0006928 movement of cell or subcellular component; GO:0042330 taxis; GO:0040011 locomotion; GO:0006952 defense response; GO:0009987 cellular process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0015629 actin cytoskeleton; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005856 cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0003779 actin binding; GO:0005515 protein binding; GO:0008092 cytoskeletal protein binding; GO:0004871 signal transducer activity; GO:0005488 binding; ","K14957","LSP1; lymphocyte-specific protein 1","hsa05152 Tuberculosis - Homo sapiens (human); hsa04625 C-type lectin receptor signaling pathway - Homo sapiens (human); "]
["P33527","Multidrug resistance-associated protein 1 OS=Homo sapiens OX=9606 GN=ABCC1","ABCC1",171.59,5.0672,1.2,2,2,2,0.949,1.06,0.938,1.09,1.041,0.933,1.04,0.56,"plasma membrane\r","GO:0098661 inorganic anion transmembrane transport; GO:0072337 modified amino acid transport; GO:0090662 ATP hydrolysis coupled transmembrane transport; GO:1901568 fatty acid derivative metabolic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0034635 glutathione transport; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0051180 vitamin transport; GO:0042886 amide transport; GO:0006690 icosanoid metabolic process; GO:0009235 cobalamin metabolic process; GO:0006629 lipid metabolic process; GO:0044765 single-organism transport; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0006810 transport; GO:0042221 response to chemical; GO:0044710 single-organism metabolic process; GO:0033013 tetrapyrrole metabolic process; GO:0006082 organic acid metabolic process; GO:0015833 peptide transport; GO:0015698 inorganic anion transport; GO:0043436 oxoacid metabolic process; GO:0033559 unsaturated fatty acid metabolic process; GO:0034220 ion transmembrane transport; GO:0006725 cellular aromatic compound metabolic process; GO:0034775 glutathione transmembrane transport; GO:0035461 vitamin transmembrane transport; GO:0050896 response to stimulus; GO:0035443 tripeptide transmembrane transport; GO:0098656 anion transmembrane transport; GO:0071704 organic substance metabolic process; GO:0042939 tripeptide transport; GO:0042493 response to drug; GO:0006766 vitamin metabolic process; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0006857 oligopeptide transport; GO:0009987 cellular process; GO:0099131 ATP hydrolysis coupled ion transmembrane transport; GO:0006767 water-soluble vitamin metabolic process; GO:0042908 xenobiotic transport; GO:0006855 drug transmembrane transport; GO:0072348 sulfur compound transport; GO:0098660 inorganic ion transmembrane transport; GO:0006691 leukotriene metabolic process; GO:0015889 cobalamin transport; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0006631 fatty acid metabolic process; GO:0044238 primary metabolic process; GO:0006820 anion transport; GO:0099133 ATP hydrolysis coupled anion transmembrane transport; GO:0055085 transmembrane transport; GO:0035672 oligopeptide transmembrane transport; GO:0015711 organic anion transport; GO:0006811 ion transport; GO:0019752 carboxylic acid metabolic process; GO:0015893 drug transport; GO:0051179 localization; GO:0071705 nitrogen compound transport; GO:1901564 organonitrogen compound metabolic process; ","GO:0016323 basolateral plasma membrane; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031226 intrinsic component of plasma membrane; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0044459 plasma membrane part; GO:0098590 plasma membrane region; GO:0044464 cell part; GO:0044425 membrane part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0042625 ATPase coupled ion transmembrane transporter activity; GO:1901265 nucleoside phosphate binding; GO:0015399 primary active transmembrane transporter activity; GO:0042910 xenobiotic transporter activity; GO:0022892 substrate-specific transporter activity; GO:0090482 vitamin transmembrane transporter activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0051183 vitamin transporter activity; GO:1904680 peptide transmembrane transporter activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0015198 oligopeptide transporter activity; GO:0016887 ATPase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0072349 modified amino acid transmembrane transporter activity; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043492 ATPase activity, coupled to movement of substances; GO:0032550 purine ribonucleoside binding; GO:0042887 amide transmembrane transporter activity; GO:0043168 anion binding; GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; GO:0015235 cobalamin transporter activity; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0008559 xenobiotic-transporting ATPase activity; GO:0090484 drug transporter activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005215 transporter activity; GO:0022804 active transmembrane transporter activity; GO:0015420 cobalamin-transporting ATPase activity; GO:0005524 ATP binding; GO:0034634 glutathione transmembrane transporter activity; GO:0015075 ion transmembrane transporter activity; GO:0015238 drug transmembrane transporter activity; GO:0022853 active ion transmembrane transporter activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0043225 ATPase-coupled anion transmembrane transporter activity; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0042937 tripeptide transporter activity; GO:1901682 sulfur compound transmembrane transporter activity; GO:0032549 ribonucleoside binding; GO:0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity; GO:0097367 carbohydrate derivative binding; GO:0035673 oligopeptide transmembrane transporter activity; GO:0042626 ATPase activity, coupled to transmembrane movement of substances; GO:0042623 ATPase activity, coupled; GO:0015431 glutathione S-conjugate-exporting ATPase activity; GO:0071997 glutathione S-conjugate-transporting ATPase activity; GO:0032555 purine ribonucleotide binding; GO:0015197 peptide transporter activity; GO:0001883 purine nucleoside binding; GO:0008514 organic anion transmembrane transporter activity; GO:0008509 anion transmembrane transporter activity; GO:0036094 small molecule binding; GO:0022857 transmembrane transporter activity; ","K05665","ABCC1; ATP-binding cassette, subfamily C (CFTR/MRP), member 1","hsa01523 Antifolate resistance - Homo sapiens (human); hsa05206 MicroRNAs in cancer - Homo sapiens (human); hsa04071 Sphingolipid signaling pathway - Homo sapiens (human); hsa02010 ABC transporters - Homo sapiens (human); hsa04977 Vitamin digestion and absorption - Homo sapiens (human); ","IPR003593; IPR003439; IPR027417; IPR011527; ","\"AAA+ ATPase domain; ABC transporter-like; P-loop containing nucleoside triphosphate hydrolase; ABC transporter type 1, transmembrane domain; \"\r"]
["P34096","Ribonuclease 4 OS=Homo sapiens OX=9606 GN=RNASE4","RNASE4",16.84,21.516,48.3,6,10,6,1.138,1.142,1.111,0.908,1.005,0.851,0.815,0.0136,"extracellular\r","GO:0006725 cellular aromatic compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0016070 RNA metabolic process; GO:0008152 metabolic process; GO:0090501 RNA phosphodiester bond hydrolysis; GO:0046483 heterocycle metabolic process; GO:0090304 nucleic acid metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic; GO:0090305 nucleic acid phosphodiester bond hydrolysis; GO:0006379 mRNA cleavage; GO:0016071 mRNA metabolic process; GO:0009987 cellular process; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0004522 ribonuclease A activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters; GO:0003676 nucleic acid binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0004518 nuclease activity; GO:0004521 endoribonuclease activity; GO:0016787 hydrolase activity; GO:0004519 endonuclease activity; GO:0004540 ribonuclease activity; GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters; ","K16632",null,null,"IPR023412; ","Ribonuclease A-domain; \r"]
["P34896","Serine hydroxymethyltransferase, cytosolic OS=Homo sapiens OX=9606 GN=SHMT1","SHMT1",53.082,80.219,25.9,9,12,8,1.064,1.008,0.952,0.975,1.003,0.973,0.976,0.522,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0009157 deoxyribonucleoside monophosphate biosynthetic process; GO:0044237 cellular metabolic process; GO:0009263 deoxyribonucleotide biosynthetic process; GO:0006231 dTMP biosynthetic process; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0065003 macromolecular complex assembly; GO:1901607 alpha-amino acid biosynthetic process; GO:0046112 nucleobase biosynthetic process; GO:0072527 pyrimidine-containing compound metabolic process; GO:0009719 response to endogenous stimulus; GO:0051716 cellular response to stimulus; GO:0014070 response to organic cyclic compound; GO:0018130 heterocycle biosynthetic process; GO:0046653 tetrahydrofolate metabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006578 amino-acid betaine biosynthetic process; GO:0072521 purine-containing compound metabolic process; GO:0006732 coenzyme metabolic process; GO:0090407 organophosphate biosynthetic process; GO:0046395 carboxylic acid catabolic process; GO:1901575 organic substance catabolic process; GO:0010243 response to organonitrogen compound; GO:0044710 single-organism metabolic process; GO:1901698 response to nitrogen compound; GO:0009112 nucleobase metabolic process; GO:0009063 cellular amino acid catabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0043436 oxoacid metabolic process; GO:0051260 protein homooligomerization; GO:0009177 pyrimidine deoxyribonucleoside monophosphate biosynthetic process; GO:1901700 response to oxygen-containing compound; GO:0097164 ammonium ion metabolic process; GO:0006221 pyrimidine nucleotide biosynthetic process; GO:0051259 protein oligomerization; GO:0046655 folic acid metabolic process; GO:0046483 heterocycle metabolic process; GO:0071229 cellular response to acid chemical; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0009265 2'-deoxyribonucleotide biosynthetic process; GO:0044248 cellular catabolic process; GO:0006545 glycine biosynthetic process; GO:0009070 serine family amino acid biosynthetic process; GO:0006461 protein complex assembly; GO:0006767 water-soluble vitamin metabolic process; GO:0008652 cellular amino acid biosynthetic process; GO:0009176 pyrimidine deoxyribonucleoside monophosphate metabolic process; GO:0006565 L-serine catabolic process; GO:1904481 response to tetrahydrofolate; GO:0044711 single-organism biosynthetic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0071407 cellular response to organic cyclic compound; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901605 alpha-amino acid metabolic process; GO:0006144 purine nucleobase metabolic process; GO:1901576 organic substance biosynthetic process; GO:0006220 pyrimidine nucleotide metabolic process; GO:0006793 phosphorus metabolic process; GO:0044283 small molecule biosynthetic process; GO:0016054 organic acid catabolic process; GO:0019637 organophosphate metabolic process; GO:0046385 deoxyribose phosphate biosynthetic process; GO:0019264 glycine biosynthetic process from serine; GO:0009123 nucleoside monophosphate metabolic process; GO:0046073 dTMP metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:1901606 alpha-amino acid catabolic process; GO:0046148 pigment biosynthetic process; GO:0001101 response to acid chemical; GO:0016053 organic acid biosynthetic process; GO:0009117 nucleotide metabolic process; GO:0009130 pyrimidine nucleoside monophosphate biosynthetic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0045329 carnitine biosynthetic process; GO:0006544 glycine metabolic process; GO:0009262 deoxyribonucleotide metabolic process; GO:0035999 tetrahydrofolate interconversion; GO:0006796 phosphate-containing compound metabolic process; GO:0009162 deoxyribonucleoside monophosphate metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0019692 deoxyribose phosphate metabolic process; GO:0051262 protein tetramerization; GO:0022607 cellular component assembly; GO:0006753 nucleoside phosphate metabolic process; GO:0070887 cellular response to chemical stimulus; GO:0071822 protein complex subunit organization; GO:0009113 purine nucleobase biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0006577 amino-acid betaine metabolic process; GO:0009219 pyrimidine deoxyribonucleotide metabolic process; GO:0051186 cofactor metabolic process; GO:0071417 cellular response to organonitrogen compound; GO:0046394 carboxylic acid biosynthetic process; GO:0009129 pyrimidine nucleoside monophosphate metabolic process; GO:0042221 response to chemical; GO:0009069 serine family amino acid metabolic process; GO:0009071 serine family amino acid catabolic process; GO:1901699 cellular response to nitrogen compound; GO:0072522 purine-containing compound biosynthetic process; GO:0006563 L-serine metabolic process; GO:0009437 carnitine metabolic process; GO:0006082 organic acid metabolic process; GO:0006760 folic acid-containing compound metabolic process; GO:0070271 protein complex biogenesis; GO:0043648 dicarboxylic acid metabolic process; GO:0016043 cellular component organization; GO:0009165 nucleotide biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0071310 cellular response to organic substance; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:0009394 2'-deoxyribonucleotide metabolic process; GO:0071704 organic substance metabolic process; GO:1904482 cellular response to tetrahydrofolate; GO:0072528 pyrimidine-containing compound biosynthetic process; GO:0006766 vitamin metabolic process; GO:0051289 protein homotetramerization; GO:0006575 cellular modified amino acid metabolic process; GO:0006730 one-carbon metabolic process; GO:0009221 pyrimidine deoxyribonucleotide biosynthetic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0009124 nucleoside monophosphate biosynthetic process; GO:0042440 pigment metabolic process; GO:0044712 single-organism catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044282 small molecule catabolic process; GO:0044249 cellular biosynthetic process; GO:0042558 pteridine-containing compound metabolic process; GO:0043933 macromolecular complex subunit organization; GO:1901565 organonitrogen compound catabolic process; GO:1901701 cellular response to oxygen-containing compound; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0071495 cellular response to endogenous stimulus; GO:0019752 carboxylic acid metabolic process; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016597 amino acid binding; GO:0046983 protein dimerization activity; GO:0070905 serine binding; GO:0043167 ion binding; GO:0008732 L-allo-threonine aldolase activity; GO:0043177 organic acid binding; GO:0016741 transferase activity, transferring one-carbon groups; GO:0016829 lyase activity; GO:0005515 protein binding; GO:0048037 cofactor binding; GO:0030170 pyridoxal phosphate binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0042802 identical protein binding; GO:0031406 carboxylic acid binding; GO:0003824 catalytic activity; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0016830 carbon-carbon lyase activity; GO:0004372 glycine hydroxymethyltransferase activity; GO:0043169 cation binding; GO:0004793 threonine aldolase activity; GO:0043168 anion binding; GO:0016742 hydroxymethyl-, formyl- and related transferase activity; GO:0016832 aldehyde-lyase activity; GO:0016740 transferase activity; GO:0036094 small molecule binding; ","K00600","glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]","hsa00670 One carbon pool by folate - Homo sapiens (human); hsa01523 Antifolate resistance - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00260 Glycine, serine and threonine metabolism - Homo sapiens (human); hsa01230 Biosynthesis of amino acids - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); hsa00630 Glyoxylate and dicarboxylate metabolism - Homo sapiens (human); ","IPR015424; IPR015422; IPR015421; ","\"Pyridoxal phosphate-dependent transferase; Pyridoxal phosphate-dependent transferase, major region, subdomain 2; Pyridoxal phosphate-dependent transferase, major region, subdomain 1; \"\r"]
["P34949","Mannose-6-phosphate isomerase OS=Homo sapiens OX=9606 GN=MPI","MPI",46.655,52.699,13.7,4,5,4,1.014,1.045,0.982,0.96,1.044,0.991,0.985,0.636,"mitochondria\r","GO:0009226 nucleotide-sugar biosynthetic process; GO:0031506 cell wall glycoprotein biosynthetic process; GO:0044085 cellular component biogenesis; GO:0043413 macromolecule glycosylation; GO:0006057 mannoprotein biosynthetic process; GO:0044036 cell wall macromolecule metabolic process; GO:0044699 single-organism process; GO:0006002 fructose 6-phosphate metabolic process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071554 cell wall organization or biogenesis; GO:0000032 cell wall mannoprotein biosynthetic process; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0009298 GDP-mannose biosynthetic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006486 protein glycosylation; GO:0018130 heterocycle biosynthetic process; GO:0009101 glycoprotein biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0009100 glycoprotein metabolic process; GO:0005975 carbohydrate metabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0042546 cell wall biogenesis; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0036211 protein modification process; GO:1901362 organic cyclic compound biosynthetic process; GO:0061611 mannose to fructose-6-phosphate metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0006013 mannose metabolic process; GO:0070589 cellular component macromolecule biosynthetic process; GO:0071704 organic substance metabolic process; GO:0006056 mannoprotein metabolic process; GO:0019673 GDP-mannose metabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0005996 monosaccharide metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0070085 glycosylation; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0044038 cell wall macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0019637 organophosphate metabolic process; GO:0009225 nucleotide-sugar metabolic process; GO:0043412 macromolecule modification; GO:0019318 hexose metabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016853 isomerase activity; GO:0046914 transition metal ion binding; GO:0004476 mannose-6-phosphate isomerase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0016860 intramolecular oxidoreductase activity; GO:0008270 zinc ion binding; GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses; ","K01809","manA; mannose-6-phosphate isomerase [EC:5.3.1.8]","hsa00051 Fructose and mannose metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00520 Amino sugar and nucleotide sugar metabolism - Homo sapiens (human); ","IPR011051; IPR014710; ","RmlC-like cupin domain; RmlC-like jelly roll fold; \r"]
["P35052","Glypican-1 OS=Homo sapiens OX=9606 GN=GPC1","GPC1",61.68,28.638,10.9,5,6,5,0.946,0.947,1.072,1.093,1.106,0.939,1.058,0.453,"extracellular\r","GO:0044085 cellular component biogenesis; GO:0030201 heparan sulfate proteoglycan metabolic process; GO:0007272 ensheathment of neurons; GO:0014037 Schwann cell differentiation; GO:0032989 cellular component morphogenesis; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0030203 glycosaminoglycan metabolic process; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0051240 positive regulation of multicellular organismal process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0007422 peripheral nervous system development; GO:0006790 sulfur compound metabolic process; GO:0007399 nervous system development; GO:0048699 generation of neurons; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0009100 glycoprotein metabolic process; GO:0090287 regulation of cellular response to growth factor stimulus; GO:0048812 neuron projection morphogenesis; GO:0048870 cell motility; GO:0006935 chemotaxis; GO:0032501 multicellular organismal process; GO:0006027 glycosaminoglycan catabolic process; GO:0042552 myelination; GO:0000902 cell morphogenesis; GO:1901575 organic substance catabolic process; GO:0050900 leukocyte migration; GO:0042063 gliogenesis; GO:0006029 proteoglycan metabolic process; GO:0030163 protein catabolic process; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0016101 diterpenoid metabolic process; GO:0042330 taxis; GO:0051094 positive regulation of developmental process; GO:1901863 positive regulation of muscle tissue development; GO:0043436 oxoacid metabolic process; GO:0048641 regulation of skeletal muscle tissue development; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0045597 positive regulation of cell differentiation; GO:0051239 regulation of multicellular organismal process; GO:0009653 anatomical structure morphogenesis; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0007409 axonogenesis; GO:0045844 positive regulation of striated muscle tissue development; GO:0044248 cellular catabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0007275 multicellular organism development; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0009966 regulation of signal transduction; GO:0040036 regulation of fibroblast growth factor receptor signaling pathway; GO:0006720 isoprenoid metabolic process; GO:0006516 glycoprotein catabolic process; GO:0006023 aminoglycan biosynthetic process; GO:0048731 system development; GO:0010927 cellular component assembly involved in morphogenesis; GO:1901136 carbohydrate derivative catabolic process; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0030200 heparan sulfate proteoglycan catabolic process; GO:0030182 neuron differentiation; GO:0097485 neuron projection guidance; GO:0006928 movement of cell or subcellular component; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:1901564 organonitrogen compound metabolic process; GO:0051674 localization of cell; GO:0009968 negative regulation of signal transduction; GO:0006024 glycosaminoglycan biosynthetic process; GO:0048869 cellular developmental process; GO:0048666 neuron development; GO:0006026 aminoglycan catabolic process; GO:0023051 regulation of signaling; GO:0048634 regulation of muscle organ development; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:2001014 regulation of skeletal muscle cell differentiation; GO:0010646 regulation of cell communication; GO:0032990 cell part morphogenesis; GO:0022607 cellular component assembly; GO:0048858 cell projection morphogenesis; GO:0006629 lipid metabolic process; GO:0032502 developmental process; GO:0030167 proteoglycan catabolic process; GO:0048522 positive regulation of cellular process; GO:0048636 positive regulation of muscle organ development; GO:0016202 regulation of striated muscle tissue development; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0030030 cell projection organization; GO:0048643 positive regulation of skeletal muscle tissue development; GO:0040011 locomotion; GO:0044273 sulfur compound catabolic process; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0016043 cellular component organization; GO:0016477 cell migration; GO:0008366 axon ensheathment; GO:0050896 response to stimulus; GO:1901566 organonitrogen compound biosynthetic process; GO:0007411 axon guidance; GO:0048468 cell development; GO:0000904 cell morphogenesis involved in differentiation; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway; GO:0090288 negative regulation of cellular response to growth factor stimulus; GO:0032288 myelin assembly; GO:0001523 retinoid metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006022 aminoglycan metabolic process; GO:0045595 regulation of cell differentiation; GO:0044265 cellular macromolecule catabolic process; GO:0044712 single-organism catabolic process; GO:1901861 regulation of muscle tissue development; GO:0006807 nitrogen compound metabolic process; GO:0048585 negative regulation of response to stimulus; GO:0031175 neuron projection development; GO:0048518 positive regulation of biological process; GO:0010001 glial cell differentiation; GO:0061564 axon development; GO:1901565 organonitrogen compound catabolic process; GO:0044767 single-organism developmental process; GO:0009057 macromolecule catabolic process; GO:0006721 terpenoid metabolic process; GO:2001016 positive regulation of skeletal muscle cell differentiation; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0098857 membrane microdomain; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0005764 lysosome; GO:0098589 membrane region; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0005768 endosome; GO:0045121 membrane raft; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0031226 intrinsic component of plasma membrane; GO:0031225 anchored component of membrane; GO:0044446 intracellular organelle part; GO:0005796 Golgi lumen; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0043202 lysosomal lumen; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0031012 extracellular matrix; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0044437 vacuolar part; GO:0005578 proteinaceous extracellular matrix; GO:0005773 vacuole; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0019838 growth factor binding; GO:0043167 ion binding; GO:0043394 proteoglycan binding; GO:0043395 heparan sulfate proteoglycan binding; GO:0005515 protein binding; GO:0005507 copper ion binding; GO:1901681 sulfur compound binding; GO:0050840 extracellular matrix binding; GO:0097367 carbohydrate derivative binding; GO:0046914 transition metal ion binding; GO:0043236 laminin binding; GO:0005488 binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0001948 glycoprotein binding; GO:0017134 fibroblast growth factor binding; ","K08107","GPC1; glypican 1","hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human); "]
["P35221","Catenin alpha-1 OS=Homo sapiens OX=9606 GN=CTNNA1","CTNNA1",100.07,323.31,32.2,25,48,17,0.934,0.959,0.967,1.005,1.043,1.039,1.079,0.00838,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0010941 regulation of cell death; GO:0022414 reproductive process; GO:0008584 male gonad development; GO:0008285 negative regulation of cell proliferation; GO:0022610 biological adhesion; GO:0030036 actin cytoskeleton organization; GO:0065003 macromolecular complex assembly; GO:0032879 regulation of localization; GO:0044702 single organism reproductive process; GO:0034332 adherens junction organization; GO:0009719 response to endogenous stimulus; GO:0071681 cellular response to indole-3-methanol; GO:0007155 cell adhesion; GO:0008104 protein localization; GO:0051147 regulation of muscle cell differentiation; GO:0007399 nervous system development; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0003006 developmental process involved in reproduction; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0016264 gap junction assembly; GO:1901099 negative regulation of signal transduction in absence of ligand; GO:0007163 establishment or maintenance of cell polarity; GO:0097306 cellular response to alcohol; GO:2000146 negative regulation of cell motility; GO:0032501 multicellular organismal process; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0051291 protein heterooligomerization; GO:0050768 negative regulation of neurogenesis; GO:0010243 response to organonitrogen compound; GO:0048513 animal organ development; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0008585 female gonad development; GO:0098602 single organism cell adhesion; GO:0051149 positive regulation of muscle cell differentiation; GO:0009887 animal organ morphogenesis; GO:0010721 negative regulation of cell development; GO:0051094 positive regulation of developmental process; GO:0048609 multicellular organismal reproductive process; GO:0060548 negative regulation of cell death; GO:0097435 supramolecular fiber organization; GO:0043068 positive regulation of programmed cell death; GO:1902692 regulation of neuroblast proliferation; GO:0050794 regulation of cellular process; GO:0000003 reproduction; GO:2001239 regulation of extrinsic apoptotic signaling pathway in absence of ligand; GO:0044707 single-multicellular organism process; GO:0033554 cellular response to stress; GO:0008589 regulation of smoothened signaling pathway; GO:0072091 regulation of stem cell proliferation; GO:0042127 regulation of cell proliferation; GO:1901700 response to oxygen-containing compound; GO:0008406 gonad development; GO:0043067 regulation of programmed cell death; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0045597 positive regulation of cell differentiation; GO:0051239 regulation of multicellular organismal process; GO:0042698 ovulation cycle; GO:0051259 protein oligomerization; GO:0022602 ovulation cycle process; GO:0046545 development of primary female sexual characteristics; GO:0090136 epithelial cell-cell adhesion; GO:0009653 anatomical structure morphogenesis; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:2000145 regulation of cell motility; GO:0001541 ovarian follicle development; GO:0007548 sex differentiation; GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand; GO:0007275 multicellular organism development; GO:0034613 cellular protein localization; GO:0061458 reproductive system development; GO:0007010 cytoskeleton organization; GO:0009966 regulation of signal transduction; GO:0006461 protein complex assembly; GO:0043297 apical junction assembly; GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; GO:0006950 response to stress; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0051960 regulation of nervous system development; GO:0060284 regulation of cell development; GO:2001237 negative regulation of extrinsic apoptotic signaling pathway; GO:0071407 cellular response to organic cyclic compound; GO:0097305 response to alcohol; GO:0010033 response to organic substance; GO:0030182 neuron differentiation; GO:2001045 negative regulation of integrin-mediated signaling pathway; GO:0048678 response to axon injury; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0046546 development of primary male sexual characteristics; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:0050793 regulation of developmental process; GO:0051093 negative regulation of developmental process; GO:0009968 negative regulation of signal transduction; GO:0043627 response to estrogen; GO:0048869 cellular developmental process; GO:0048666 neuron development; GO:0023051 regulation of signaling; GO:0045216 cell-cell junction organization; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0046660 female sex differentiation; GO:2001238 positive regulation of extrinsic apoptotic signaling pathway; GO:0040013 negative regulation of locomotion; GO:0009611 response to wounding; GO:2001233 regulation of apoptotic signaling pathway; GO:0016337 single organismal cell-cell adhesion; GO:0010646 regulation of cell communication; GO:0022607 cellular component assembly; GO:0042475 odontogenesis of dentin-containing tooth; GO:2000647 negative regulation of stem cell proliferation; GO:0045596 negative regulation of cell differentiation; GO:0033036 macromolecule localization; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0071822 protein complex subunit organization; GO:0007406 negative regulation of neuroblast proliferation; GO:0048608 reproductive structure development; GO:0098609 cell-cell adhesion; GO:0048522 positive regulation of cellular process; GO:0031102 neuron projection regeneration; GO:0042476 odontogenesis; GO:0010942 positive regulation of cell death; GO:0071417 cellular response to organonitrogen compound; GO:1902589 single-organism organelle organization; GO:0071680 response to indole-3-methanol; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:2000178 negative regulation of neural precursor cell proliferation; GO:0030030 cell projection organization; GO:1901699 cellular response to nitrogen compound; GO:0007568 aging; GO:2001236 regulation of extrinsic apoptotic signaling pathway; GO:0070271 protein complex biogenesis; GO:0048856 anatomical structure development; GO:0051271 negative regulation of cellular component movement; GO:2000026 regulation of multicellular organismal development; GO:0034329 cell junction assembly; GO:0016043 cellular component organization; GO:0043069 negative regulation of programmed cell death; GO:0046661 male sex differentiation; GO:0071310 cellular response to organic substance; GO:0007015 actin filament organization; GO:0043065 positive regulation of apoptotic process; GO:0050896 response to stimulus; GO:0048468 cell development; GO:2001044 regulation of integrin-mediated signaling pathway; GO:0031103 axon regeneration; GO:0030154 cell differentiation; GO:0051961 negative regulation of nervous system development; GO:0043066 negative regulation of apoptotic process; GO:0023056 positive regulation of signaling; GO:2001235 positive regulation of apoptotic signaling pathway; GO:0010647 positive regulation of cell communication; GO:0045880 positive regulation of smoothened signaling pathway; GO:0009987 cellular process; GO:0045137 development of primary sexual characteristics; GO:0045595 regulation of cell differentiation; GO:0007043 cell-cell junction assembly; GO:0048585 negative regulation of response to stimulus; GO:0031175 neuron projection development; GO:0048518 positive regulation of biological process; GO:0043933 macromolecular complex subunit organization; GO:0051641 cellular localization; GO:0032504 multicellular organism reproduction; GO:2000177 regulation of neural precursor cell proliferation; GO:0061564 axon development; GO:0070727 cellular macromolecule localization; GO:1901701 cellular response to oxygen-containing compound; GO:0034330 cell junction organization; GO:0044767 single-organism developmental process; GO:0048511 rhythmic process; GO:0071495 cellular response to endogenous stimulus; GO:0009967 positive regulation of signal transduction; GO:0040012 regulation of locomotion; GO:0031099 regeneration; GO:0042981 regulation of apoptotic process; GO:0050767 regulation of neurogenesis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0019898 extrinsic component of membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0098857 membrane microdomain; GO:0044291 cell-cell contact zone; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005913 cell-cell adherens junction; GO:0005623 cell; GO:0005911 cell-cell junction; GO:0014704 intercalated disc; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0098590 plasma membrane region; GO:0005925 focal adhesion; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0098805 whole membrane; GO:0098589 membrane region; GO:0030027 lamellipodium; GO:0005912 adherens junction; GO:0030141 secretory granule; GO:0030055 cell-substrate junction; GO:0045121 membrane raft; GO:0043227 membrane-bounded organelle; GO:0016600 flotillin complex; GO:0005924 cell-substrate adherens junction; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0031252 cell leading edge; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0098797 plasma membrane protein complex; GO:0019897 extrinsic component of plasma membrane; GO:0070161 anchoring junction; GO:0012505 endomembrane system; GO:0005901 caveola; GO:0005829 cytosol; GO:0015629 actin cytoskeleton; GO:0043296 apical junction complex; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0001669 acrosomal vesicle; GO:0044853 plasma membrane raft; GO:0005915 zonula adherens; GO:0016342 catenin complex; GO:0005794 Golgi apparatus; GO:0097223 sperm part; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0045295 gamma-catenin binding; GO:0051015 actin filament binding; GO:0003723 RNA binding; GO:0046982 protein heterodimerization activity; GO:0046983 protein dimerization activity; GO:0044877 macromolecular complex binding; GO:0005515 protein binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0050839 cell adhesion molecule binding; GO:0008092 cytoskeletal protein binding; GO:0017166 vinculin binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0003676 nucleic acid binding; GO:0003779 actin binding; GO:0005198 structural molecule activity; GO:0008013 beta-catenin binding; GO:0032403 protein complex binding; ","K05691","CTNNA; catenin alpha","hsa04390 Hippo signaling pathway - Homo sapiens (human); hsa05100 Bacterial invasion of epithelial cells - Homo sapiens (human); hsa04670 Leukocyte transendothelial migration - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa04520 Adherens junction - Homo sapiens (human); hsa05226 Gastric cancer - Homo sapiens (human); hsa05213 Endometrial cancer - Homo sapiens (human); hsa05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human); "]
["P35237","Serpin B6 OS=Homo sapiens OX=9606 GN=SERPINB6","SERPINB6",42.621,55.662,39.9,11,16,11,1.093,1,1.066,0.954,0.967,0.937,0.905,0.0237,"cytoplasm\r","GO:0045321 leukocyte activation; GO:0044699 single-organism process; GO:0050877 neurological system process; GO:0051234 establishment of localization; GO:0010466 negative regulation of peptidase activity; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0052548 regulation of endopeptidase activity; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0007600 sensory perception; GO:0006970 response to osmotic stress; GO:0071214 cellular response to abiotic stimulus; GO:0080090 regulation of primary metabolic process; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0051336 regulation of hydrolase activity; GO:0032940 secretion by cell; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0071470 cellular response to osmotic stress; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0043299 leukocyte degranulation; GO:0052547 regulation of peptidase activity; GO:0050954 sensory perception of mechanical stimulus; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0010951 negative regulation of endopeptidase activity; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0009628 response to abiotic stimulus; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:0051346 negative regulation of hydrolase activity; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0045861 negative regulation of proteolysis; GO:0003008 system process; GO:0006950 response to stress; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0030162 regulation of proteolysis; GO:0043312 neutrophil degranulation; GO:0009892 negative regulation of metabolic process; GO:0002263 cell activation involved in immune response; GO:0002366 leukocyte activation involved in immune response; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:0051246 regulation of protein metabolic process; GO:0001775 cell activation; GO:0051248 negative regulation of protein metabolic process; GO:0007605 sensory perception of sound; GO:0051179 localization; GO:0006955 immune response; GO:0006887 exocytosis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070821 tertiary granule membrane; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0070820 tertiary granule; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0030667 secretory granule membrane; GO:0101003 ficolin-1-rich granule membrane; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0002020 protease binding; GO:0004867 serine-type endopeptidase inhibitor activity; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0030414 peptidase inhibitor activity; GO:0061134 peptidase regulator activity; GO:0061135 endopeptidase regulator activity; GO:0005515 protein binding; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0004866 endopeptidase inhibitor activity; GO:0019899 enzyme binding; ","K13963","SERPINB; serpin B","hsa05146 Amoebiasis - Homo sapiens (human); ","IPR023796; ","Serpin domain; \r"]
["P35268","60S ribosomal protein L22 OS=Homo sapiens OX=9606 GN=RPL22","RPL22",14.787,11.193,18.8,2,5,2,0.818,0.796,0.872,1.116,1.106,1.091,1.333,0.000496,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0006518 peptide metabolic process; GO:0045321 leukocyte activation; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0042110 T cell activation; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0002181 cytoplasmic translation; GO:0070972 protein localization to endoplasmic reticulum; GO:0006364 rRNA processing; GO:0033365 protein localization to organelle; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0008104 protein localization; GO:0006396 RNA processing; GO:0018130 heterocycle biosynthetic process; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0072657 protein localization to membrane; GO:0044763 single-organism cellular process; GO:0042254 ribosome biogenesis; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032774 RNA biosynthetic process; GO:0045047 protein targeting to ER; GO:0002520 immune system development; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0048513 animal organ development; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0046907 intracellular transport; GO:0044707 single-multicellular organism process; GO:0044267 cellular protein metabolic process; GO:0048519 negative regulation of biological process; GO:0030098 lymphocyte differentiation; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0044248 cellular catabolic process; GO:0007275 multicellular organism development; GO:0034655 nucleobase-containing compound catabolic process; GO:0034613 cellular protein localization; GO:0090150 establishment of protein localization to membrane; GO:0046631 alpha-beta T cell activation; GO:0030217 T cell differentiation; GO:0048731 system development; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0071702 organic substance transport; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0045184 establishment of protein localization; GO:0001775 cell activation; GO:0051179 localization; GO:1901564 organonitrogen compound metabolic process; GO:0072594 establishment of protein localization to organelle; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0051649 establishment of localization in cell; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0006413 translational initiation; GO:1901361 organic cyclic compound catabolic process; GO:0006412 translation; GO:0033036 macromolecule localization; GO:0032502 developmental process; GO:0034470 ncRNA processing; GO:0016072 rRNA metabolic process; GO:0010468 regulation of gene expression; GO:0002521 leukocyte differentiation; GO:0043043 peptide biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0006401 RNA catabolic process; GO:0016070 RNA metabolic process; GO:0046632 alpha-beta T cell differentiation; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0019222 regulation of metabolic process; GO:0019083 viral transcription; GO:0048856 anatomical structure development; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0006613 cotranslational protein targeting to membrane; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0016032 viral process; GO:0006886 intracellular protein transport; GO:0019080 viral gene expression; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0006807 nitrogen compound metabolic process; GO:0046649 lymphocyte activation; GO:0030097 hemopoiesis; GO:0048534 hematopoietic or lymphoid organ development; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0070727 cellular macromolecule localization; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044767 single-organism developmental process; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0009056 catabolic process; GO:0034660 ncRNA metabolic process; GO:0065007 biological regulation; GO:0046700 heterocycle catabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0044421 extracellular region part; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0044391 ribosomal subunit; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030055 cell-substrate junction; GO:0044445 cytosolic part; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0022626 cytosolic ribosome; GO:0043229 intracellular organelle; GO:0005840 ribosome; GO:0043232 intracellular non-membrane-bounded organelle; GO:0022625 cytosolic large ribosomal subunit; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0031012 extracellular matrix; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0015934 large ribosomal subunit; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0097367 carbohydrate derivative binding; GO:0005488 binding; GO:0043167 ion binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0043168 anion binding; GO:0008201 heparin binding; GO:0005539 glycosaminoglycan binding; GO:0003735 structural constituent of ribosome; GO:0005198 structural molecule activity; GO:1901681 sulfur compound binding; ","K02891","RP-L22e; large subunit ribosomal protein L22e","hsa03010 Ribosome - Homo sapiens (human); "]
["P35270","Sepiapterin reductase OS=Homo sapiens OX=9606 GN=SPR","SPR",28.048,62.873,37.2,8,8,8,1.046,1.058,1.092,0.97,0.88,0.864,0.849,0.0125,"mitochondria\r","GO:0051188 cofactor biosynthetic process; GO:0042559 pteridine-containing compound biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0046209 nitric oxide metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0072593 reactive oxygen species metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006729 tetrahydrobiopterin biosynthetic process; GO:2001057 reactive nitrogen species metabolic process; GO:0009108 coenzyme biosynthetic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0046146 tetrahydrobiopterin metabolic process; GO:0009987 cellular process; GO:1903409 reactive oxygen species biosynthetic process; GO:0018130 heterocycle biosynthetic process; GO:0055114 oxidation-reduction process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0006732 coenzyme metabolic process; GO:1901576 organic substance biosynthetic process; GO:0051341 regulation of oxidoreductase activity; GO:0042558 pteridine-containing compound metabolic process; GO:0044249 cellular biosynthetic process; GO:0051186 cofactor metabolic process; GO:0050789 regulation of biological process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0032768 regulation of monooxygenase activity; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0050999 regulation of nitric-oxide synthase activity; GO:0006809 nitric oxide biosynthetic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0065007 biological regulation; GO:1901564 organonitrogen compound metabolic process; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0000166 nucleotide binding; GO:0004757 sepiapterin reductase activity; GO:0048037 cofactor binding; GO:0016491 oxidoreductase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016614 oxidoreductase activity, acting on CH-OH group of donors; GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; GO:0003824 catalytic activity; GO:0005488 binding; GO:0050661 NADP binding; GO:0004033 aldo-keto reductase (NADP) activity; GO:0036094 small molecule binding; GO:0050662 coenzyme binding; ","K00072","SPR; sepiapterin reductase [EC:1.1.1.153]","hsa00790 Folate biosynthesis - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR016040; ","NAD(P)-binding domain; \r"]
["P35442","Thrombospondin-2 OS=Homo sapiens OX=9606 GN=THBS2","THBS2",129.99,33.795,13.1,13,12,11,0.945,0.978,0.98,0.988,0.991,0.994,1.024,0.182,"extracellular\r","GO:0050794 regulation of cellular process; GO:2000181 negative regulation of blood vessel morphogenesis; GO:0051093 negative regulation of developmental process; GO:0065008 regulation of biological quality; GO:0050803 regulation of synapse structure or activity; GO:0051965 positive regulation of synapse assembly; GO:0051960 regulation of nervous system development; GO:0051963 regulation of synapse assembly; GO:0051962 positive regulation of nervous system development; GO:1901342 regulation of vasculature development; GO:0048522 positive regulation of cellular process; GO:0051241 negative regulation of multicellular organismal process; GO:0044087 regulation of cellular component biogenesis; GO:0048519 negative regulation of biological process; GO:0048518 positive regulation of biological process; GO:1901343 negative regulation of vasculature development; GO:0051239 regulation of multicellular organismal process; GO:0050807 regulation of synapse organization; GO:0051130 positive regulation of cellular component organization; GO:0022610 biological adhesion; GO:0050789 regulation of biological process; GO:0016525 negative regulation of angiogenesis; GO:0051240 positive regulation of multicellular organismal process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0007155 cell adhesion; GO:0045765 regulation of angiogenesis; GO:0051128 regulation of cellular component organization; GO:0051094 positive regulation of developmental process; GO:0050793 regulation of developmental process; GO:0044089 positive regulation of cellular component biogenesis; GO:0065007 biological regulation; GO:2000026 regulation of multicellular organismal development; ","GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0044420 extracellular matrix component; GO:0005576 extracellular region; GO:0005604 basement membrane; GO:0031012 extracellular matrix; GO:0043226 organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0005578 proteinaceous extracellular matrix; GO:0030141 secretory granule; GO:0031091 platelet alpha granule; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0097367 carbohydrate derivative binding; GO:0005488 binding; GO:0043167 ion binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0043168 anion binding; GO:0005509 calcium ion binding; GO:0008201 heparin binding; GO:0005539 glycosaminoglycan binding; GO:1901681 sulfur compound binding; ","K04659","THBS2S; thrombospondin 2/3/4/5","hsa05144 Malaria - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa04512 ECM-receptor interaction - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); ","IPR001007; IPR001881; IPR008859; IPR000742; IPR001791; IPR024731; IPR013320; ","\"VWFC domain; EGF-like calcium-binding domain; Thrombospondin, C-terminal; EGF-like domain; Laminin G domain; EGF domain; Concanavalin A-like lectin/glucanase domain; \"\r"]
["P35556","Fibrillin-2 OS=Homo sapiens OX=9606 GN=FBN2","FBN2",314.77,22.168,3.1,9,19,3,1.13,1.098,1.208,0.865,0.89,0.869,0.764,0.000819,"extracellular\r","GO:0065008 regulation of biological quality; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0070169 positive regulation of biomineral tissue development; GO:0044699 single-organism process; GO:0030500 regulation of bone mineralization; GO:1903845 negative regulation of cellular response to transforming growth factor beta stimulus; GO:0070167 regulation of biomineral tissue development; GO:0035107 appendage morphogenesis; GO:0010646 regulation of cell communication; GO:0048562 embryonic organ morphogenesis; GO:0051240 positive regulation of multicellular organismal process; GO:0060343 trabecula formation; GO:0022617 extracellular matrix disassembly; GO:0060173 limb development; GO:0030198 extracellular matrix organization; GO:0009790 embryo development; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0090596 sensory organ morphogenesis; GO:0048598 embryonic morphogenesis; GO:0035113 embryonic appendage morphogenesis; GO:0045667 regulation of osteoblast differentiation; GO:0032502 developmental process; GO:0048592 eye morphogenesis; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0035583 sequestering of TGFbeta in extracellular matrix; GO:0090287 regulation of cellular response to growth factor stimulus; GO:0060346 bone trabecula formation; GO:0061383 trabecula morphogenesis; GO:0032501 multicellular organismal process; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0045669 positive regulation of osteoblast differentiation; GO:1900116 extracellular negative regulation of signal transduction; GO:0048583 regulation of response to stimulus; GO:0009887 animal organ morphogenesis; GO:0051094 positive regulation of developmental process; GO:0048856 anatomical structure development; GO:0001501 skeletal system development; GO:2000026 regulation of multicellular organismal development; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0043010 camera-type eye development; GO:1900115 extracellular regulation of signal transduction; GO:0048568 embryonic organ development; GO:0061430 bone trabecula morphogenesis; GO:0045778 positive regulation of ossification; GO:0017015 regulation of transforming growth factor beta receptor signaling pathway; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0045597 positive regulation of cell differentiation; GO:0051239 regulation of multicellular organismal process; GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0009653 anatomical structure morphogenesis; GO:0001654 eye development; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0043062 extracellular structure organization; GO:0090288 negative regulation of cellular response to growth factor stimulus; GO:0035581 sequestering of extracellular ligand from receptor; GO:0048048 embryonic eye morphogenesis; GO:0007275 multicellular organism development; GO:0051235 maintenance of location; GO:0009987 cellular process; GO:0009966 regulation of signal transduction; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0045595 regulation of cell differentiation; GO:0045185 maintenance of protein location; GO:0048731 system development; GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway; GO:0048585 negative regulation of response to stimulus; GO:0048518 positive regulation of biological process; GO:0071694 maintenance of protein location in extracellular region; GO:0048705 skeletal system morphogenesis; GO:1903844 regulation of cellular response to transforming growth factor beta stimulus; GO:0048736 appendage development; GO:0044767 single-organism developmental process; GO:0030326 embryonic limb morphogenesis; GO:0035108 limb morphogenesis; GO:0030278 regulation of ossification; GO:0030501 positive regulation of bone mineralization; GO:0022411 cellular component disassembly; GO:0007423 sensory organ development; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0071692 protein localization to extracellular region; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0031012 extracellular matrix; GO:0044421 extracellular region part; GO:0005578 proteinaceous extracellular matrix; GO:0099512 supramolecular fiber; GO:0001527 microfibril; GO:0099080 supramolecular complex; GO:0044420 extracellular matrix component; GO:0005576 extracellular region; GO:0099081 supramolecular polymer; ","GO:0005201 extracellular matrix structural constituent; GO:0005488 binding; GO:0043167 ion binding; GO:0030023 extracellular matrix constituent conferring elasticity; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0005509 calcium ion binding; GO:0005198 structural molecule activity; GO:0097493 structural molecule activity conferring elasticity; ",{"$nulls":3},"IPR026823; IPR017878; IPR001881; IPR000742; IPR009030; ","Complement Clr-like EGF domain; TB domain; EGF-like calcium-binding domain; EGF-like domain; Growth factor receptor cysteine-rich domain; \r"]
["P35579","Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9","MYH9",226.53,323.31,55.7,117,285,96,0.933,0.908,0.922,1.074,1.069,1.087,1.169,7.69e-05,"cyto_nucl\r","GO:0044700 single organism signaling; GO:0090130 tissue migration; GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0032270 positive regulation of cellular protein metabolic process; GO:0007166 cell surface receptor signaling pathway; GO:0022414 reproductive process; GO:0043009 chordate embryonic development; GO:0032989 cellular component morphogenesis; GO:0006949 syncytium formation; GO:0015031 protein transport; GO:0042110 T cell activation; GO:0022610 biological adhesion; GO:0043542 endothelial cell migration; GO:0008152 metabolic process; GO:0030036 actin cytoskeleton organization; GO:0001525 angiogenesis; GO:0008360 regulation of cell shape; GO:0044702 single organism reproductive process; GO:1903918 regulation of actin filament severing; GO:0007155 cell adhesion; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0009790 embryo development; GO:0008104 protein localization; GO:0044765 single-organism transport; GO:0051716 cellular response to stimulus; GO:0006911 phagocytosis, engulfment; GO:0030168 platelet activation; GO:0080090 regulation of primary metabolic process; GO:0000212 meiotic spindle organization; GO:0044763 single-organism cellular process; GO:0002520 immune system development; GO:0007163 establishment or maintenance of cell polarity; GO:0048870 cell motility; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0000902 cell morphogenesis; GO:0006810 transport; GO:0031532 actin cytoskeleton reorganization; GO:0000226 microtubule cytoskeleton organization; GO:0048513 animal organ development; GO:0050900 leukocyte migration; GO:0010631 epithelial cell migration; GO:0001701 in utero embryonic development; GO:0098602 single organism cell adhesion; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051301 cell division; GO:0050817 coagulation; GO:1903317 regulation of protein maturation; GO:0051640 organelle localization; GO:0006509 membrane protein ectodomain proteolysis; GO:0000003 reproduction; GO:0072359 circulatory system development; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0007051 spindle organization; GO:0090132 epithelium migration; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0034109 homotypic cell-cell adhesion; GO:0099024 plasma membrane invagination; GO:0009653 anatomical structure morphogenesis; GO:0000910 cytokinesis; GO:1902578 single-organism localization; GO:0010628 positive regulation of gene expression; GO:0061061 muscle structure development; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0051295 establishment of meiotic spindle localization; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0006950 response to stress; GO:0048731 system development; GO:0000768 syncytium formation by plasma membrane fusion; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0072358 cardiovascular system development; GO:0071702 organic substance transport; GO:0032970 regulation of actin filament-based process; GO:0030162 regulation of proteolysis; GO:0051656 establishment of organelle localization; GO:0044238 primary metabolic process; GO:0007017 microtubule-based process; GO:0045184 establishment of protein localization; GO:0051247 positive regulation of protein metabolic process; GO:0007520 myoblast fusion; GO:0006996 organelle organization; GO:0001767 establishment of lymphocyte polarity; GO:0031325 positive regulation of cellular metabolic process; GO:0030029 actin filament-based process; GO:0061024 membrane organization; GO:0070613 regulation of protein processing; GO:0001775 cell activation; GO:0006928 movement of cell or subcellular component; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0030048 actin filament-based movement; GO:0014902 myotube differentiation; GO:0051674 localization of cell; GO:0001568 blood vessel development; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0033619 membrane protein proteolysis; GO:0051234 establishment of localization; GO:0006909 phagocytosis; GO:0009611 response to wounding; GO:0016337 single organismal cell-cell adhesion; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0048514 blood vessel morphogenesis; GO:0033036 macromolecule localization; GO:0032502 developmental process; GO:0032796 uropod organization; GO:0031032 actomyosin structure organization; GO:0010468 regulation of gene expression; GO:1903919 negative regulation of actin filament severing; GO:0002521 leukocyte differentiation; GO:0098609 cell-cell adhesion; GO:0001944 vasculature development; GO:0048522 positive regulation of cellular process; GO:0051321 meiotic cell cycle; GO:0030220 platelet formation; GO:0023052 signaling; GO:0007229 integrin-mediated signaling pathway; GO:1902589 single-organism organelle organization; GO:1903131 mononuclear cell differentiation; GO:1903923 positive regulation of protein processing in phagocytic vesicle; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0030030 cell projection organization; GO:0001667 ameboidal-type cell migration; GO:0019222 regulation of metabolic process; GO:0040011 locomotion; GO:0048856 anatomical structure development; GO:0070527 platelet aggregation; GO:0016043 cellular component organization; GO:0016477 cell migration; GO:1903046 meiotic cell cycle process; GO:1903319 positive regulation of protein maturation; GO:0043534 blood vessel endothelial cell migration; GO:0060255 regulation of macromolecule metabolic process; GO:0051653 spindle localization; GO:0010324 membrane invagination; GO:0050896 response to stimulus; GO:0007599 hemostasis; GO:0048468 cell development; GO:0071704 organic substance metabolic process; GO:0000904 cell morphogenesis involved in differentiation; GO:0030154 cell differentiation; GO:0045862 positive regulation of proteolysis; GO:0030010 establishment of cell polarity; GO:0006508 proteolysis; GO:1903921 regulation of protein processing in phagocytic vesicle; GO:0009987 cellular process; GO:0051293 establishment of spindle localization; GO:0051146 striated muscle cell differentiation; GO:0001768 establishment of T cell polarity; GO:0050878 regulation of body fluid levels; GO:0030099 myeloid cell differentiation; GO:0009792 embryo development ending in birth or egg hatching; GO:0036344 platelet morphogenesis; GO:0046649 lymphocyte activation; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0030097 hemopoiesis; GO:0048534 hematopoietic or lymphoid organ development; GO:0051641 cellular localization; GO:0010954 positive regulation of protein processing; GO:0042060 wound healing; GO:0002573 myeloid leukocyte differentiation; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0042692 muscle cell differentiation; GO:0051128 regulation of cellular component organization; GO:0022402 cell cycle process; GO:0022604 regulation of cell morphogenesis; GO:0007049 cell cycle; GO:0030224 monocyte differentiation; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0098862 cluster of actin-based cell projections; GO:0044421 extracellular region part; GO:0099568 cytoplasmic region; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0005913 cell-cell adherens junction; GO:0005623 cell; GO:0032155 cell division site part; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0016460 myosin II complex; GO:0097513 myosin II filament; GO:0030055 cell-substrate junction; GO:0016459 myosin complex; GO:0043227 membrane-bounded organelle; GO:0042641 actomyosin; GO:0005924 cell-substrate adherens junction; GO:0031252 cell leading edge; GO:0042995 cell projection; GO:0044430 cytoskeletal part; GO:0070161 anchoring junction; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0070938 contractile ring; GO:0043231 intracellular membrane-bounded organelle; GO:0031012 extracellular matrix; GO:0001772 immunological synapse; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0005826 actomyosin contractile ring; GO:0005938 cell cortex; GO:0005903 brush border; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0030863 cortical cytoskeleton; GO:0044424 intracellular part; GO:0030864 cortical actin cytoskeleton; GO:0005911 cell-cell junction; GO:0032432 actin filament bundle; GO:0005856 cytoskeleton; GO:0015630 microtubule cytoskeleton; GO:0044464 cell part; GO:0044425 membrane part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0001725 stress fiber; GO:0032154 cleavage furrow; GO:0032982 myosin filament; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0097610 cell surface furrow; GO:0031594 neuromuscular junction; GO:0001931 uropod; GO:0044446 intracellular organelle part; GO:0032153 cell division site; GO:0097517 contractile actin filament bundle; GO:0031254 cell trailing edge; GO:0005829 cytosol; GO:0005819 spindle; GO:0015629 actin cytoskeleton; GO:0045202 synapse; GO:0043226 organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0044448 cell cortex part; GO:0001726 ruffle; GO:0009986 cell surface; GO:0044444 cytoplasmic part; ","GO:0051015 actin filament binding; GO:1901265 nucleoside phosphate binding; GO:0003774 motor activity; GO:0046983 protein dimerization activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0016887 ATPase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0042802 identical protein binding; GO:0008092 cytoskeletal protein binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0045296 cadherin binding; GO:0032550 purine ribonucleoside binding; GO:0043531 ADP binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0000146 microfilament motor activity; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0030898 actin-dependent ATPase activity; GO:0035639 purine ribonucleoside triphosphate binding; GO:0017076 purine nucleotide binding; GO:0003723 RNA binding; GO:0005524 ATP binding; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0005516 calmodulin binding; GO:0043495 protein anchor; GO:0050839 cell adhesion molecule binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0042803 protein homodimerization activity; GO:0003676 nucleic acid binding; GO:0042623 ATPase activity, coupled; GO:0003779 actin binding; GO:0019904 protein domain specific binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0032403 protein complex binding; GO:0036094 small molecule binding; ","K10352","MYH; myosin heavy chain","hsa05132 Salmonella infection - Homo sapiens (human); hsa04530 Tight junction - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa04270 Vascular smooth muscle contraction - Homo sapiens (human); ","IPR002928; IPR016137; IPR004009; IPR027417; IPR001609; IPR027401; ","\"Myosin tail; RGS domain; Myosin, N-terminal, SH3-like; P-loop containing nucleoside triphosphate hydrolase; Myosin head, motor domain; Myosin-like IQ motif-containing domain; \"\r"]
["P35580","Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10","MYH10",229,189.75,25.2,45,79,26,1.088,1.114,1.078,0.931,0.884,0.908,0.83,0.000479,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0043009 chordate embryonic development; GO:0007420 brain development; GO:0051647 nucleus localization; GO:0032989 cellular component morphogenesis; GO:0050877 neurological system process; GO:0007097 nuclear migration; GO:0021537 telencephalon development; GO:0009605 response to external stimulus; GO:0022610 biological adhesion; GO:0030036 actin cytoskeleton organization; GO:0007507 heart development; GO:0008360 regulation of cell shape; GO:0007155 cell adhesion; GO:0009790 embryo development; GO:0055013 cardiac muscle cell development; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0006930 substrate-dependent cell migration, cell extension; GO:0007399 nervous system development; GO:0000278 mitotic cell cycle; GO:0060537 muscle tissue development; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0048812 neuron projection morphogenesis; GO:0048870 cell motility; GO:0007009 plasma membrane organization; GO:0006935 chemotaxis; GO:0032501 multicellular organismal process; GO:0060976 coronary vasculature development; GO:0006810 transport; GO:0000902 cell morphogenesis; GO:0021549 cerebellum development; GO:0099563 modification of synaptic structure; GO:0048513 animal organ development; GO:0021670 lateral ventricle development; GO:0055002 striated muscle cell development; GO:0001701 in utero embryonic development; GO:0007417 central nervous system development; GO:0042330 taxis; GO:0051301 cell division; GO:0021695 cerebellar cortex development; GO:0097435 supramolecular fiber organization; GO:0055001 muscle cell development; GO:0051640 organelle localization; GO:0072359 circulatory system development; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0055006 cardiac cell development; GO:0007512 adult heart development; GO:1903047 mitotic cell cycle process; GO:0009653 anatomical structure morphogenesis; GO:0055007 cardiac muscle cell differentiation; GO:0001654 eye development; GO:1902578 single-organism localization; GO:0000910 cytokinesis; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0021591 ventricular system development; GO:0030239 myofibril assembly; GO:0007409 axonogenesis; GO:0061061 muscle structure development; GO:0030900 forebrain development; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0050885 neuromuscular process controlling balance; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0030902 hindbrain development; GO:0055015 ventricular cardiac muscle cell development; GO:0035051 cardiocyte differentiation; GO:0006950 response to stress; GO:0003279 cardiac septum development; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0010927 cellular component assembly involved in morphogenesis; GO:0008283 cell proliferation; GO:0072358 cardiovascular system development; GO:0099010 modification of postsynaptic structure; GO:0051656 establishment of organelle localization; GO:0050808 synapse organization; GO:0030031 cell projection assembly; GO:0030182 neuron differentiation; GO:0061640 cytoskeleton-dependent cytokinesis; GO:0097485 neuron projection guidance; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0030029 actin filament-based process; GO:0006928 movement of cell or subcellular component; GO:0007423 sensory organ development; GO:0051179 localization; GO:0050905 neuromuscular process; GO:0050793 regulation of developmental process; GO:0006887 exocytosis; GO:0030048 actin filament-based movement; GO:0055012 ventricular cardiac muscle cell differentiation; GO:0010256 endomembrane system organization; GO:0051674 localization of cell; GO:0001568 blood vessel development; GO:0001778 plasma membrane repair; GO:0048869 cellular developmental process; GO:0048666 neuron development; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0040023 establishment of nucleus localization; GO:0051234 establishment of localization; GO:0009611 response to wounding; GO:0051649 establishment of localization in cell; GO:0022607 cellular component assembly; GO:0032990 cell part morphogenesis; GO:0048858 cell projection morphogenesis; GO:0060322 head development; GO:0001764 neuron migration; GO:0006929 substrate-dependent cell migration; GO:0055003 cardiac myofibril assembly; GO:0032502 developmental process; GO:0031032 actomyosin structure organization; GO:0009888 tissue development; GO:0001944 vasculature development; GO:0035904 aorta development; GO:1902589 single-organism organelle organization; GO:0021680 cerebellar Purkinje cell layer development; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0030030 cell projection organization; GO:0032940 secretion by cell; GO:0060840 artery development; GO:0022037 metencephalon development; GO:0040011 locomotion; GO:0021592 fourth ventricle development; GO:0048856 anatomical structure development; GO:0014706 striated muscle tissue development; GO:0016477 cell migration; GO:0016043 cellular component organization; GO:0043010 camera-type eye development; GO:0048738 cardiac muscle tissue development; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0007411 axon guidance; GO:0000904 cell morphogenesis involved in differentiation; GO:0030154 cell differentiation; GO:0070925 organelle assembly; GO:0009987 cellular process; GO:0060041 retina development in camera-type eye; GO:0051146 striated muscle cell differentiation; GO:0003008 system process; GO:0009792 embryo development ending in birth or egg hatching; GO:0000281 mitotic cytokinesis; GO:0044802 single-organism membrane organization; GO:0031175 neuron projection development; GO:0098885 modification of postsynaptic actin cytoskeleton; GO:0003205 cardiac chamber development; GO:0051641 cellular localization; GO:0061564 axon development; GO:0042060 wound healing; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0042692 muscle cell differentiation; GO:0022402 cell cycle process; GO:0051128 regulation of cellular component organization; GO:0022604 regulation of cell morphogenesis; GO:0007049 cell cycle; GO:0021678 third ventricle development; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0030425 dendrite; GO:0098862 cluster of actin-based cell projections; GO:0044421 extracellular region part; GO:0099568 cytoplasmic region; GO:0005737 cytoplasm; GO:0043025 neuronal cell body; GO:0032991 macromolecular complex; GO:0005623 cell; GO:0032155 cell division site part; GO:0044422 organelle part; GO:0043197 dendritic spine; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0016460 myosin II complex; GO:0030027 lamellipodium; GO:0097513 myosin II filament; GO:0043005 neuron projection; GO:0016459 myosin complex; GO:0043227 membrane-bounded organelle; GO:0042641 actomyosin; GO:0097458 neuron part; GO:0031252 cell leading edge; GO:0042995 cell projection; GO:0044430 cytoskeletal part; GO:0030496 midbody; GO:0030427 site of polarized growth; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0030424 axon; GO:0098794 postsynapse; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0005903 brush border; GO:0005938 cell cortex; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0030426 growth cone; GO:0032432 actin filament bundle; GO:0005856 cytoskeleton; GO:0044309 neuron spine; GO:0015630 microtubule cytoskeleton; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0001725 stress fiber; GO:0032154 cleavage furrow; GO:0032982 myosin filament; GO:0044456 synapse part; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0097610 cell surface furrow; GO:0031594 neuromuscular junction; GO:0044446 intracellular organelle part; GO:0032153 cell division site; GO:0097517 contractile actin filament bundle; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0005819 spindle; GO:0015629 actin cytoskeleton; GO:0045202 synapse; GO:0043226 organelle; GO:0005634 nucleus; GO:0036477 somatodendritic compartment; GO:0044297 cell body; GO:0009986 cell surface; GO:0044444 cytoplasmic part; ","GO:0051015 actin filament binding; GO:1901265 nucleoside phosphate binding; GO:0003774 motor activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0016887 ATPase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0008092 cytoskeletal protein binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043531 ADP binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0000146 microfilament motor activity; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0030898 actin-dependent ATPase activity; GO:0035639 purine ribonucleoside triphosphate binding; GO:0017076 purine nucleotide binding; GO:0005524 ATP binding; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0005516 calmodulin binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0042623 ATPase activity, coupled; GO:0003779 actin binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0032403 protein complex binding; GO:0036094 small molecule binding; ","K10352","MYH; myosin heavy chain","hsa05132 Salmonella infection - Homo sapiens (human); hsa04530 Tight junction - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa04270 Vascular smooth muscle contraction - Homo sapiens (human); ","IPR002928; IPR004009; IPR027417; IPR008989; IPR001609; IPR027401; ","\"Myosin tail; Myosin, N-terminal, SH3-like; P-loop containing nucleoside triphosphate hydrolase; Myosin S1 fragment, N-terminal; Myosin head, motor domain; Myosin-like IQ motif-containing domain; \"\r"]
["P35610","Sterol O-acyltransferase 1 OS=Homo sapiens OX=9606 GN=SOAT1","SOAT1",64.734,6.1926,2.5,1,2,1,1.109,1.115,1.143,0.885,0.896,0.876,0.789,3.57E-5,"plasma membrane\r","GO:0044085 cellular component biogenesis; GO:0015850 organic hydroxy compound transport; GO:0065008 regulation of biological quality; GO:0033344 cholesterol efflux; GO:0030301 cholesterol transport; GO:0006066 alcohol metabolic process; GO:0048869 cellular developmental process; GO:0009891 positive regulation of biosynthetic process; GO:0034379 very-low-density lipoprotein particle assembly; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:1903020 positive regulation of glycoprotein metabolic process; GO:0022607 cellular component assembly; GO:0009893 positive regulation of metabolic process; GO:0065003 macromolecular complex assembly; GO:0030258 lipid modification; GO:0071825 protein-lipid complex subunit organization; GO:0010742 macrophage derived foam cell differentiation; GO:0033036 macromolecule localization; GO:0055088 lipid homeostasis; GO:0044765 single-organism transport; GO:0006629 lipid metabolic process; GO:0032502 developmental process; GO:0071827 plasma lipoprotein particle organization; GO:0042986 positive regulation of amyloid precursor protein biosynthetic process; GO:0034433 steroid esterification; GO:0034435 cholesterol esterification; GO:0006869 lipid transport; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0044281 small molecule metabolic process; GO:0010559 regulation of glycoprotein biosynthetic process; GO:0044763 single-organism cellular process; GO:0008202 steroid metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0034377 plasma lipoprotein particle assembly; GO:0044710 single-organism metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0019222 regulation of metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0065005 protein-lipid complex assembly; GO:0090077 foam cell differentiation; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0015918 sterol transport; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:1901615 organic hydroxy compound metabolic process; GO:1902652 secondary alcohol metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0016125 sterol metabolic process; GO:0071704 organic substance metabolic process; GO:0034434 sterol esterification; GO:0097006 regulation of plasma lipoprotein particle levels; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:1902578 single-organism localization; GO:0009889 regulation of biosynthetic process; GO:0006898 receptor-mediated endocytosis; GO:0051235 maintenance of location; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0010560 positive regulation of glycoprotein biosynthetic process; GO:0010878 cholesterol storage; GO:0008203 cholesterol metabolic process; GO:0016192 vesicle-mediated transport; GO:1903018 regulation of glycoprotein metabolic process; GO:0071702 organic substance transport; GO:0010556 regulation of macromolecule biosynthetic process; GO:0042984 regulation of amyloid precursor protein biosynthetic process; GO:0010876 lipid localization; GO:0006897 endocytosis; GO:0042632 cholesterol homeostasis; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0043933 macromolecular complex subunit organization; GO:0051247 positive regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0055092 sterol homeostasis; GO:0019915 lipid storage; GO:0031328 positive regulation of cellular biosynthetic process; GO:0051179 localization; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044432 endoplasmic reticulum part; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; ","GO:0015485 cholesterol binding; GO:0032934 sterol binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups; GO:1901681 sulfur compound binding; GO:0048037 cofactor binding; GO:0005496 steroid binding; GO:0097159 organic cyclic compound binding; GO:0016746 transferase activity, transferring acyl groups; GO:0003824 catalytic activity; GO:0000062 fatty-acyl-CoA binding; GO:0043178 alcohol binding; GO:0005488 binding; GO:0004772 sterol O-acyltransferase activity; GO:0008289 lipid binding; GO:0043168 anion binding; GO:0016740 transferase activity; GO:0034736 cholesterol O-acyltransferase activity; GO:0008374 O-acyltransferase activity; GO:0050662 coenzyme binding; GO:0036094 small molecule binding; ","K00637","SOAT; sterol O-acyltransferase [EC:2.3.1.26]","hsa00100 Steroid biosynthesis - Homo sapiens (human); hsa04979 Cholesterol metabolism - Homo sapiens (human); "]
["P35613","Basigin OS=Homo sapiens OX=9606 GN=BSG","BSG",42.2,19.594,10.9,4,6,4,0.985,1.095,1.015,0.98,0.977,0.991,0.953,0.273,"endoplasmic reticulum\r","GO:0044700 single organism signaling; GO:0010256 endomembrane system organization; GO:0051674 localization of cell; GO:0022414 reproductive process; GO:0007166 cell surface receptor signaling pathway; GO:0007566 embryo implantation; GO:0046683 response to organophosphorus; GO:0044699 single-organism process; GO:0090002 establishment of protein localization to plasma membrane; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0001893 maternal placenta development; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0046697 decidualization; GO:0006612 protein targeting to membrane; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0015718 monocarboxylic acid transport; GO:0042475 odontogenesis of dentin-containing tooth; GO:0044706 multi-multicellular organism process; GO:0044702 single organism reproductive process; GO:0022617 extracellular matrix disassembly; GO:0009719 response to endogenous stimulus; GO:0032787 monocarboxylic acid metabolic process; GO:0046689 response to mercury ion; GO:0010035 response to inorganic substance; GO:0030198 extracellular matrix organization; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:1901652 response to peptide; GO:0044765 single-organism transport; GO:0032502 developmental process; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0003006 developmental process involved in reproduction; GO:0009888 tissue development; GO:0072657 protein localization to membrane; GO:0044281 small molecule metabolic process; GO:0048608 reproductive structure development; GO:0044763 single-organism cellular process; GO:0048870 cell motility; GO:0007009 plasma membrane organization; GO:0046942 carboxylic acid transport; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0010038 response to metal ion; GO:0051704 multi-organism process; GO:1902582 single-organism intracellular transport; GO:0042476 odontogenesis; GO:0006810 transport; GO:0010243 response to organonitrogen compound; GO:0048513 animal organ development; GO:0042221 response to chemical; GO:0050900 leukocyte migration; GO:0050789 regulation of biological process; GO:0043434 response to peptide hormone; GO:0051591 response to cAMP; GO:0044710 single-organism metabolic process; GO:1901698 response to nitrogen compound; GO:0009887 animal organ morphogenesis; GO:0040011 locomotion; GO:0006082 organic acid metabolic process; GO:0048609 multicellular organismal reproductive process; GO:0048856 anatomical structure development; GO:0043436 oxoacid metabolic process; GO:0050794 regulation of cellular process; GO:0000003 reproduction; GO:0016477 cell migration; GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0044707 single-multicellular organism process; GO:0072661 protein targeting to plasma membrane; GO:0060135 maternal process involved in female pregnancy; GO:0001890 placenta development; GO:1901700 response to oxygen-containing compound; GO:0050896 response to stimulus; GO:1990778 protein localization to cell periphery; GO:0071704 organic substance metabolic process; GO:0009653 anatomical structure morphogenesis; GO:0007565 female pregnancy; GO:0006090 pyruvate metabolic process; GO:1902578 single-organism localization; GO:0043062 extracellular structure organization; GO:0014074 response to purine-containing compound; GO:0006886 intracellular protein transport; GO:1902580 single-organism cellular localization; GO:0007275 multicellular organism development; GO:0061458 reproductive system development; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0090150 establishment of protein localization to membrane; GO:0048731 system development; GO:0044802 single-organism membrane organization; GO:0002376 immune system process; GO:0071702 organic substance transport; GO:0010033 response to organic substance; GO:0015849 organic acid transport; GO:0051641 cellular localization; GO:0006820 anion transport; GO:0032504 multicellular organism reproduction; GO:0045184 establishment of protein localization; GO:0015711 organic anion transport; GO:0072659 protein localization to plasma membrane; GO:0070727 cellular macromolecule localization; GO:0006811 ion transport; GO:0044767 single-organism developmental process; GO:0061024 membrane organization; GO:0044703 multi-organism reproductive process; GO:0019752 carboxylic acid metabolic process; GO:0022411 cellular component disassembly; GO:0006928 movement of cell or subcellular component; GO:0009725 response to hormone; GO:0051179 localization; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0098857 membrane microdomain; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0048770 pigment granule; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0099503 secretory vesicle; GO:0098589 membrane region; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0030055 cell-substrate junction; GO:0030141 secretory granule; GO:0045121 membrane raft; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0031226 intrinsic component of plasma membrane; GO:0098588 bounding membrane of organelle; GO:0042470 melanosome; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0000139 Golgi membrane; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0005739 mitochondrion; GO:0002080 acrosomal membrane; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0030667 secretory granule membrane; GO:0044459 plasma membrane part; GO:0001669 acrosomal vesicle; GO:0097223 sperm part; GO:0005794 Golgi apparatus; GO:0042383 sarcolemma; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005342 organic acid transmembrane transporter activity; GO:0015075 ion transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0048029 monosaccharide binding; GO:0008028 monocarboxylic acid transmembrane transporter activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0050839 cell adhesion molecule binding; GO:0005488 binding; GO:0005537 mannose binding; GO:0045296 cadherin binding; GO:0030246 carbohydrate binding; GO:0008514 organic anion transmembrane transporter activity; GO:0036094 small molecule binding; GO:0005215 transporter activity; GO:0008509 anion transmembrane transporter activity; GO:0022857 transmembrane transporter activity; GO:0046943 carboxylic acid transmembrane transporter activity; ","K06535",null,null,"IPR003598; IPR007110; IPR013783; IPR003599; ","Immunoglobulin subtype 2; Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin subtype; \r"]
["P35658","Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214","NUP214",213.62,43.041,5.7,10,11,10,0.974,1.01,1.048,0.99,0.971,1.016,0.982,0.509,"plasma membrane\r","GO:0050658 RNA transport; GO:0065008 regulation of biological quality; GO:0010608 posttranscriptional regulation of gene expression; GO:0051169 nuclear transport; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:1902583 multi-organism intracellular transport; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0032879 regulation of localization; GO:0015931 nucleobase-containing compound transport; GO:0033365 protein localization to organelle; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0006606 protein import into nucleus; GO:0075733 intracellular transport of virus; GO:0044419 interspecies interaction between organisms; GO:0008104 protein localization; GO:0051031 tRNA transport; GO:0044765 single-organism transport; GO:0007077 mitotic nuclear envelope disassembly; GO:0000278 mitotic cell cycle; GO:0018130 heterocycle biosynthetic process; GO:0044763 single-organism cellular process; GO:0032774 RNA biosynthetic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0006611 protein export from nucleus; GO:0051704 multi-organism process; GO:0006810 transport; GO:0080135 regulation of cellular response to stress; GO:0031047 gene silencing by RNA; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0006913 nucleocytoplasmic transport; GO:0006464 cellular protein modification process; GO:1901362 organic cyclic compound biosynthetic process; GO:0050794 regulation of cellular process; GO:0016925 protein sumoylation; GO:0046907 intracellular transport; GO:0051028 mRNA transport; GO:1902593 single-organism nuclear import; GO:0044267 cellular protein metabolic process; GO:0080134 regulation of response to stress; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0051236 establishment of RNA localization; GO:0043487 regulation of RNA stability; GO:0046483 heterocycle metabolic process; GO:1902578 single-organism localization; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0051081 nuclear envelope disassembly; GO:0044744 protein targeting to nucleus; GO:1902580 single-organism cellular localization; GO:0034613 cellular protein localization; GO:0046794 transport of virus; GO:0006403 RNA localization; GO:0006405 RNA export from nucleus; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0045184 establishment of protein localization; GO:0044766 multi-organism transport; GO:0006409 tRNA export from nucleus; GO:0032446 protein modification by small protein conjugation; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0051179 localization; GO:0043412 macromolecule modification; GO:0010256 endomembrane system organization; GO:0072594 establishment of protein localization to organelle; GO:0017038 protein import; GO:0044699 single-organism process; GO:1902581 multi-organism cellular localization; GO:0051168 nuclear export; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0051234 establishment of localization; GO:0071431 tRNA-containing ribonucleoprotein complex export from nucleus; GO:0006605 protein targeting; GO:0071427 mRNA-containing ribonucleoprotein complex export from nucleus; GO:0051649 establishment of localization in cell; GO:0050657 nucleic acid transport; GO:0033036 macromolecule localization; GO:0010827 regulation of glucose transport; GO:0051726 regulation of cell cycle; GO:0010468 regulation of gene expression; GO:1901360 organic cyclic compound metabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0010605 negative regulation of macromolecule metabolic process; GO:1902582 single-organism intracellular transport; GO:0071166 ribonucleoprotein complex localization; GO:0016070 RNA metabolic process; GO:0050789 regulation of biological process; GO:0030397 membrane disassembly; GO:0090304 nucleic acid metabolic process; GO:0019222 regulation of metabolic process; GO:1900034 regulation of cellular response to heat; GO:0019083 viral transcription; GO:0036211 protein modification process; GO:1902579 multi-organism localization; GO:0006997 nucleus organization; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0071704 organic substance metabolic process; GO:0006998 nuclear envelope organization; GO:0018205 peptidyl-lysine modification; GO:0016032 viral process; GO:0006886 intracellular protein transport; GO:0019080 viral gene expression; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006406 mRNA export from nucleus; GO:0010629 negative regulation of gene expression; GO:0051049 regulation of transport; GO:0006807 nitrogen compound metabolic process; GO:0044802 single-organism membrane organization; GO:0043488 regulation of mRNA stability; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0018193 peptidyl-amino acid modification; GO:0070727 cellular macromolecule localization; GO:0016458 gene silencing; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0051170 nuclear import; GO:0071426 ribonucleoprotein complex export from nucleus; GO:0022411 cellular component disassembly; GO:0010467 gene expression; GO:0022402 cell cycle process; GO:0034504 protein localization to nucleus; GO:0071705 nitrogen compound transport; GO:0007049 cell cycle; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0030054 cell junction; GO:0044613 nuclear pore central transport channel; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005925 focal adhesion; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0005912 adherens junction; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005643 nuclear pore; GO:0005635 nuclear envelope; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0044615 nuclear pore nuclear basket; GO:0005829 cytosol; GO:1990876 cytoplasmic side of nuclear pore; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0031975 envelope; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005048 signal sequence binding; GO:0005487 nucleocytoplasmic transporter activity; GO:0008565 protein transporter activity; GO:0042277 peptide binding; GO:0005488 binding; GO:0008139 nuclear localization sequence binding; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0033218 amide binding; GO:0005049 nuclear export signal receptor activity; GO:0017056 structural constituent of nuclear pore; GO:0005198 structural molecule activity; GO:0005215 transporter activity; ","K14317","NUP214; nuclear pore complex protein Nup214","hsa05169 Epstein-Barr virus infection - Homo sapiens (human); hsa03013 RNA transport - Homo sapiens (human); ","IPR015943; ","WD40/YVTN repeat-like-containing domain; \r"]
["P35754","Glutaredoxin-1 OS=Homo sapiens OX=9606 GN=GLRX","GLRX",11.776,40.361,30.2,2,4,2,0.878,1.049,0.969,1.095,0.972,1.044,1.074,0.304,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0002028 regulation of sodium ion transport; GO:0065008 regulation of biological quality; GO:0034764 positive regulation of transmembrane transport; GO:0006725 cellular aromatic compound metabolic process; GO:0032411 positive regulation of transporter activity; GO:0015949 nucleobase-containing small molecule interconversion; GO:0045454 cell redox homeostasis; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0080058 protein deglutathionylation; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0032879 regulation of localization; GO:0010765 positive regulation of sodium ion transport; GO:0044093 positive regulation of molecular function; GO:0032414 positive regulation of ion transmembrane transporter activity; GO:0010959 regulation of metal ion transport; GO:0034641 cellular nitrogen compound metabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0045838 positive regulation of membrane potential; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0032409 regulation of transporter activity; GO:1904062 regulation of cation transmembrane transport; GO:0051049 regulation of transport; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0043269 regulation of ion transport; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0019725 cellular homeostasis; GO:0022898 regulation of transmembrane transporter activity; GO:2000649 regulation of sodium ion transmembrane transporter activity; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0042391 regulation of membrane potential; GO:0051050 positive regulation of transport; GO:0034762 regulation of transmembrane transport; GO:0043270 positive regulation of ion transport; GO:0050789 regulation of biological process; GO:0034765 regulation of ion transmembrane transport; GO:0034767 positive regulation of ion transmembrane transport; GO:1904064 positive regulation of cation transmembrane transport; GO:2000651 positive regulation of sodium ion transmembrane transporter activity; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0065009 regulation of molecular function; GO:0006464 cellular protein modification process; GO:1902305 regulation of sodium ion transmembrane transport; GO:0032412 regulation of ion transmembrane transporter activity; GO:1902307 positive regulation of sodium ion transmembrane transport; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0009055 electron carrier activity; GO:0015035 protein disulfide oxidoreductase activity; GO:0015036 disulfide oxidoreductase activity; GO:0047485 protein N-terminus binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016667 oxidoreductase activity, acting on a sulfur group of donors; GO:0015038 glutathione disulfide oxidoreductase activity; GO:0005515 protein binding; GO:0097573 glutathione oxidoreductase activity; GO:0015037 peptide disulfide oxidoreductase activity; GO:0016491 oxidoreductase activity; ","K03676",null,null,"IPR002109; IPR011899; IPR014025; IPR012336; ","\"Glutaredoxin; Glutaredoxin, eukaryotic/virial; Glutaredoxin subgroup; Thioredoxin-like fold; \"\r"]
["P35914","Hydroxymethylglutaryl-CoA lyase, mitochondrial OS=Homo sapiens OX=9606 GN=HMGCL","HMGCL",34.36,20.749,16,4,6,4,1.186,1.136,0.995,0.936,0.831,1.008,0.837,0.0814,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:1901606 alpha-amino acid catabolic process; GO:0001101 response to acid chemical; GO:0048732 gland development; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0051262 protein tetramerization; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0007005 mitochondrion organization; GO:1902224 ketone body metabolic process; GO:0006629 lipid metabolic process; GO:0006790 sulfur compound metabolic process; GO:0032502 developmental process; GO:0071822 protein complex subunit organization; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006732 coenzyme metabolic process; GO:0032501 multicellular organismal process; GO:0051186 cofactor metabolic process; GO:0046395 carboxylic acid catabolic process; GO:1901575 organic substance catabolic process; GO:0048513 animal organ development; GO:0042221 response to chemical; GO:0044710 single-organism metabolic process; GO:0009063 cellular amino acid catabolic process; GO:0006082 organic acid metabolic process; GO:0070271 protein complex biogenesis; GO:0048856 anatomical structure development; GO:0043436 oxoacid metabolic process; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:1901700 response to oxygen-containing compound; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0051259 protein oligomerization; GO:0033993 response to lipid; GO:0009991 response to extracellular stimulus; GO:0044248 cellular catabolic process; GO:0061008 hepaticobiliary system development; GO:0007275 multicellular organism development; GO:0009081 branched-chain amino acid metabolic process; GO:0070542 response to fatty acid; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0044711 single-organism biosynthetic process; GO:0006950 response to stress; GO:0048731 system development; GO:0044712 single-organism catabolic process; GO:0035383 thioester metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044282 small molecule catabolic process; GO:0010033 response to organic substance; GO:0046950 cellular ketone body metabolic process; GO:0007584 response to nutrient; GO:1901605 alpha-amino acid metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0006637 acyl-CoA metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0046951 ketone body biosynthetic process; GO:0009083 branched-chain amino acid catabolic process; GO:0001889 liver development; GO:0006551 leucine metabolic process; GO:1901565 organonitrogen compound catabolic process; GO:0006793 phosphorus metabolic process; GO:0044767 single-organism developmental process; GO:0006996 organelle organization; GO:0019752 carboxylic acid metabolic process; GO:0016054 organic acid catabolic process; GO:0044283 small molecule biosynthetic process; GO:0006552 leucine catabolic process; GO:0042594 response to starvation; GO:0031667 response to nutrient levels; GO:0009056 catabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0031090 organelle membrane; GO:0005777 peroxisome; GO:0031967 organelle envelope; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0031975 envelope; GO:0042579 microbody; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0000287 magnesium ion binding; GO:0005102 receptor binding; GO:0046983 protein dimerization activity; GO:0043167 ion binding; GO:0043177 organic acid binding; GO:0016829 lyase activity; GO:0005515 protein binding; GO:1901681 sulfur compound binding; GO:0048037 cofactor binding; GO:0030145 manganese ion binding; GO:0042802 identical protein binding; GO:0031406 carboxylic acid binding; GO:0046914 transition metal ion binding; GO:0016833 oxo-acid-lyase activity; GO:0000062 fatty-acyl-CoA binding; GO:0003824 catalytic activity; GO:0016830 carbon-carbon lyase activity; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0004419 hydroxymethylglutaryl-CoA lyase activity; GO:0043168 anion binding; GO:0050662 coenzyme binding; GO:0036094 small molecule binding; ","K01640","E4.1.3.4; hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4]","hsa00280 Valine, leucine and isoleucine degradation - Homo sapiens (human); hsa00650 Butanoate metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00072 Synthesis and degradation of ketone bodies - Homo sapiens (human); hsa04146 Peroxisome - Homo sapiens (human); ","IPR013785; IPR000891; ","Aldolase-type TIM barrel; Pyruvate carboxyltransferase; \r"]
["P36269","Glutathione hydrolase 5 proenzyme OS=Homo sapiens OX=9606 GN=GGT5","GGT5",62.26,39.685,10.1,5,10,5,1.126,1.042,1.132,0.924,0.951,0.946,0.855,0.0052,"extracellular\r","GO:0006518 peptide metabolic process; GO:0016053 organic acid biosynthetic process; GO:0019370 leukotriene biosynthetic process; GO:1901748 leukotriene D4 metabolic process; GO:0042398 cellular modified amino acid biosynthetic process; GO:1901568 fatty acid derivative metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0044272 sulfur compound biosynthetic process; GO:0008610 lipid biosynthetic process; GO:0046456 icosanoid biosynthetic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0043171 peptide catabolic process; GO:0006749 glutathione metabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:1901750 leukotriene D4 biosynthetic process; GO:0006690 icosanoid metabolic process; GO:0006629 lipid metabolic process; GO:0006790 sulfur compound metabolic process; GO:0043043 peptide biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006636 unsaturated fatty acid biosynthetic process; GO:0043603 cellular amide metabolic process; GO:0006633 fatty acid biosynthetic process; GO:1901575 organic substance catabolic process; GO:0046394 carboxylic acid biosynthetic process; GO:0044710 single-organism metabolic process; GO:0006954 inflammatory response; GO:0044273 sulfur compound catabolic process; GO:0006952 defense response; GO:0006082 organic acid metabolic process; GO:0019184 nonribosomal peptide biosynthetic process; GO:0043436 oxoacid metabolic process; GO:0033559 unsaturated fatty acid metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0006575 cellular modified amino acid metabolic process; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0006508 proteolysis; GO:0009987 cellular process; GO:0044711 single-organism biosynthetic process; GO:0006950 response to stress; GO:0006691 leukotriene metabolic process; GO:1901570 fatty acid derivative biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0006631 fatty acid metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:1901565 organonitrogen compound catabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0042219 cellular modified amino acid catabolic process; GO:0044283 small molecule biosynthetic process; GO:0019752 carboxylic acid metabolic process; GO:0043604 amide biosynthetic process; GO:0006751 glutathione catabolic process; GO:0072330 monocarboxylic acid biosynthetic process; GO:0009056 catabolic process; GO:0006750 glutathione biosynthetic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0031226 intrinsic component of plasma membrane; GO:0009897 external side of plasma membrane; GO:0071944 cell periphery; GO:0031225 anchored component of membrane; GO:0031224 intrinsic component of membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0046658 anchored component of plasma membrane; GO:0005886 plasma membrane; GO:0031362 anchored component of external side of plasma membrane; GO:0044459 plasma membrane part; GO:0044425 membrane part; GO:0044464 cell part; GO:0009986 cell surface; GO:0031233 intrinsic component of external side of plasma membrane; GO:0098552 side of membrane; ","GO:0016746 transferase activity, transferring acyl groups; GO:0008238 exopeptidase activity; GO:0008233 peptidase activity; GO:0003824 catalytic activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0003840 gamma-glutamyltransferase activity; GO:0016787 hydrolase activity; GO:0016740 transferase activity; GO:0036374 glutathione hydrolase activity; GO:0008242 omega peptidase activity; GO:0016755 transferase activity, transferring amino-acyl groups; ","K18592","GGT1_5; gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]","hsa00480 Glutathione metabolism - Homo sapiens (human); hsa00430 Taurine and hypotaurine metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00590 Arachidonic acid metabolism - Homo sapiens (human); ","IPR029055; ","\"Nucleophile aminohydrolases, N-terminal; \"\r"]
["P36405","ADP-ribosylation factor-like protein 3 OS=Homo sapiens OX=9606 GN=ARL3","ARL3",20.455,18.883,22.5,4,5,4,1.111,1.102,1.121,0.934,0.909,0.847,0.807,0.00188,"cytoplasm\r","GO:0098840 protein transport along microtubule; GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0007166 cell surface receptor signaling pathway; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0022008 neurogenesis; GO:0060271 cilium assembly; GO:0044699 single-organism process; GO:0007224 smoothened signaling pathway; GO:0015031 protein transport; GO:0044782 cilium organization; GO:0051234 establishment of localization; GO:0010970 transport along microtubule; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0042461 photoreceptor cell development; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0044765 single-organism transport; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0048699 generation of neurons; GO:0046530 photoreceptor cell differentiation; GO:0044763 single-organism cellular process; GO:0007264 small GTPase mediated signal transduction; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:1902582 single-organism intracellular transport; GO:0006810 transport; GO:1902589 single-organism organelle organization; GO:0048513 animal organ development; GO:0001655 urogenital system development; GO:0050789 regulation of biological process; GO:0030030 cell projection organization; GO:0099118 microtubule-based protein transport; GO:0051301 cell division; GO:0048856 anatomical structure development; GO:0031503 protein complex localization; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0046907 intracellular transport; GO:0048193 Golgi vesicle transport; GO:0072001 renal system development; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0099111 microtubule-based transport; GO:0030705 cytoskeleton-dependent intracellular transport; GO:0030154 cell differentiation; GO:1902578 single-organism localization; GO:0000910 cytokinesis; GO:0070925 organelle assembly; GO:0006886 intracellular protein transport; GO:1902580 single-organism cellular localization; GO:0007275 multicellular organism development; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0001822 kidney development; GO:0035556 intracellular signal transduction; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0042073 intraciliary transport; GO:0071702 organic substance transport; GO:0007017 microtubule-based process; GO:0030031 cell projection assembly; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0007018 microtubule-based movement; GO:0030182 neuron differentiation; GO:0070727 cellular macromolecule localization; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0006928 movement of cell or subcellular component; GO:0022402 cell cycle process; GO:0006892 post-Golgi vesicle-mediated transport; GO:0051179 localization; GO:0007049 cell cycle; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005874 microtubule; GO:0035869 ciliary transition zone; GO:0031090 organelle membrane; GO:0005881 cytoplasmic microtubule; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0097730 non-motile cilium; GO:0044424 intracellular part; GO:0099512 supramolecular fiber; GO:0005623 cell; GO:0099080 supramolecular complex; GO:0097731 9+0 non-motile cilium; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005856 cytoskeleton; GO:0005815 microtubule organizing center; GO:0044441 ciliary part; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043229 intracellular organelle; GO:0005929 cilium; GO:0042995 cell projection; GO:0099513 polymeric cytoskeletal fiber; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0030496 midbody; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0044463 cell projection part; GO:0005819 spindle; GO:0005576 extracellular region; GO:0099081 supramolecular polymer; GO:0005876 spindle microtubule; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0032391 photoreceptor connecting cilium; GO:0005813 centrosome; GO:0097733 photoreceptor cell cilium; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0008092 cytoskeletal protein binding; GO:0019003 GDP binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0008017 microtubule binding; GO:0005488 binding; GO:0003924 GTPase activity; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0017076 purine nucleotide binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0015631 tubulin binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0046872 metal ion binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0032561 guanyl ribonucleotide binding; GO:0036094 small molecule binding; ","K07944",null,null,"IPR005225; IPR027417; ","Small GTP-binding protein domain; P-loop containing nucleoside triphosphate hydrolase; \r"]
["P36542","ATP synthase subunit gamma, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1C","ATP5F1C",32.996,34.659,23.5,7,15,7,1.064,1.027,1.05,0.937,0.967,0.96,0.912,0.00278,"mitochondria\r","GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0090662 ATP hydrolysis coupled transmembrane transport; GO:0009117 nucleotide metabolic process; GO:0006839 mitochondrial transport; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0046129 purine ribonucleoside biosynthetic process; GO:0009163 nucleoside biosynthetic process; GO:0009156 ribonucleoside monophosphate biosynthetic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0046390 ribose phosphate biosynthetic process; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0006091 generation of precursor metabolites and energy; GO:1901137 carbohydrate derivative biosynthetic process; GO:0006753 nucleoside phosphate metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0009145 purine nucleoside triphosphate biosynthetic process; GO:0044765 single-organism transport; GO:0018130 heterocycle biosynthetic process; GO:0098655 cation transmembrane transport; GO:0009206 purine ribonucleoside triphosphate biosynthetic process; GO:0044281 small molecule metabolic process; GO:0006119 oxidative phosphorylation; GO:0006754 ATP biosynthetic process; GO:0044763 single-organism cellular process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0015985 energy coupled proton transport, down electrochemical gradient; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0009168 purine ribonucleoside monophosphate biosynthetic process; GO:1902582 single-organism intracellular transport; GO:0042451 purine nucleoside biosynthetic process; GO:0090407 organophosphate biosynthetic process; GO:0006810 transport; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0072522 purine-containing compound biosynthetic process; GO:0015986 ATP synthesis coupled proton transport; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0006164 purine nucleotide biosynthetic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0098662 inorganic cation transmembrane transport; GO:0009201 ribonucleoside triphosphate biosynthetic process; GO:0016310 phosphorylation; GO:0046907 intracellular transport; GO:0034220 ion transmembrane transport; GO:0009165 nucleotide biosynthetic process; GO:0042776 mitochondrial ATP synthesis coupled proton transport; GO:0006725 cellular aromatic compound metabolic process; GO:0009259 ribonucleotide metabolic process; GO:0009142 nucleoside triphosphate biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0006812 cation transport; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:1990542 mitochondrial transmembrane transport; GO:1901135 carbohydrate derivative metabolic process; GO:1902600 hydrogen ion transmembrane transport; GO:0034641 cellular nitrogen compound metabolic process; GO:1902580 single-organism cellular localization; GO:0099132 ATP hydrolysis coupled cation transmembrane transport; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0099131 ATP hydrolysis coupled ion transmembrane transport; GO:0009987 cellular process; GO:0009119 ribonucleoside metabolic process; GO:0046034 ATP metabolic process; GO:0009124 nucleoside monophosphate biosynthetic process; GO:0044711 single-organism biosynthetic process; GO:0098660 inorganic ion transmembrane transport; GO:0009127 purine nucleoside monophosphate biosynthetic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0042455 ribonucleoside biosynthetic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0006163 purine nucleotide metabolic process; GO:0006818 hydrogen transport; GO:0015992 proton transport; GO:0051641 cellular localization; GO:0046128 purine ribonucleoside metabolic process; GO:0055085 transmembrane transport; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0009152 purine ribonucleotide biosynthetic process; GO:0006793 phosphorus metabolic process; GO:1901659 glycosyl compound biosynthetic process; GO:0006811 ion transport; GO:0009260 ribonucleotide biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0051179 localization; GO:0015672 monovalent inorganic cation transport; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1); GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0043209 myelin sheath; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0019866 organelle inner membrane; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005759 mitochondrial matrix; GO:0044429 mitochondrial part; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005576 extracellular region; GO:0045259 proton-transporting ATP synthase complex; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005753 mitochondrial proton-transporting ATP synthase complex; GO:0031975 envelope; GO:0016469 proton-transporting two-sector ATPase complex; GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain; GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1); GO:0043234 protein complex; GO:0031966 mitochondrial membrane; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0042625 ATPase coupled ion transmembrane transporter activity; GO:0015399 primary active transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism; GO:0015077 monovalent inorganic cation transmembrane transporter activity; GO:0016787 hydrolase activity; GO:0015078 hydrogen ion transmembrane transporter activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0046933 proton-transporting ATP synthase activity, rotational mechanism; GO:0016887 ATPase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0019829 cation-transporting ATPase activity; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0043492 ATPase activity, coupled to movement of substances; GO:0005488 binding; GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; GO:0022890 inorganic cation transmembrane transporter activity; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005215 transporter activity; GO:0022804 active transmembrane transporter activity; GO:0003723 RNA binding; GO:0015075 ion transmembrane transporter activity; GO:0022853 active ion transmembrane transporter activity; GO:0017111 nucleoside-triphosphatase activity; GO:0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity; GO:0042626 ATPase activity, coupled to transmembrane movement of substances; GO:0003676 nucleic acid binding; GO:0042623 ATPase activity, coupled; GO:0008324 cation transmembrane transporter activity; GO:0022857 transmembrane transporter activity; ","K02136","ATPeF1G; F-type H+-transporting ATPase subunit gamma","hsa05010 Alzheimer's disease - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); "]
["P36551","Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX","CPOX",50.151,7.0902,4.4,2,3,2,1.062,0.957,0.993,1.017,0.982,0.999,0.995,0.911,"mitochondria\r","GO:0051188 cofactor biosynthetic process; GO:0046148 pigment biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0006783 heme biosynthetic process; GO:0046501 protoporphyrinogen IX metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0046685 response to arsenic-containing substance; GO:1901566 organonitrogen compound biosynthetic process; GO:0042168 heme metabolic process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0006778 porphyrin-containing compound metabolic process; GO:0008152 metabolic process; GO:0006782 protoporphyrinogen IX biosynthetic process; GO:0046483 heterocycle metabolic process; GO:0010039 response to iron ion; GO:0019438 aromatic compound biosynthetic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0051597 response to methylmercury; GO:0010035 response to inorganic substance; GO:0009987 cellular process; GO:0018130 heterocycle biosynthetic process; GO:0044711 single-organism biosynthetic process; GO:0042440 pigment metabolic process; GO:0055114 oxidation-reduction process; GO:0017085 response to insecticide; GO:0009636 response to toxic substance; GO:0006779 porphyrin-containing compound biosynthetic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0010033 response to organic substance; GO:1901576 organic substance biosynthetic process; GO:0010038 response to metal ion; GO:0044249 cellular biosynthetic process; GO:0051186 cofactor metabolic process; GO:0042221 response to chemical; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0044710 single-organism metabolic process; GO:0033013 tetrapyrrole metabolic process; GO:0010288 response to lead ion; GO:0033014 tetrapyrrole biosynthetic process; GO:1901362 organic cyclic compound biosynthetic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044429 mitochondrial part; GO:0031090 organelle membrane; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0031974 membrane-enclosed lumen; GO:0005740 mitochondrial envelope; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070013 intracellular organelle lumen; GO:0031970 organelle envelope lumen; GO:0005758 mitochondrial intermembrane space; GO:0005622 intracellular; GO:0044464 cell part; GO:0031975 envelope; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0031966 mitochondrial membrane; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; ","GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors; GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor; GO:0005212 structural constituent of eye lens; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:0004109 coproporphyrinogen oxidase activity; GO:0005198 structural molecule activity; GO:0016491 oxidoreductase activity; ","K00228","CPOX; coproporphyrinogen III oxidase [EC:1.3.3.3]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00860 Porphyrin and chlorophyll metabolism - Homo sapiens (human); "]
["P36578","60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4","RPL4",47.697,155.26,41.7,19,42,19,0.89,0.895,0.899,1.104,1.098,1.097,1.229,2.55e-07,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0072594 establishment of protein localization to organelle; GO:0006518 peptide metabolic process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0051649 establishment of localization in cell; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0070972 protein localization to endoplasmic reticulum; GO:0006364 rRNA processing; GO:0006413 translational initiation; GO:1901361 organic cyclic compound catabolic process; GO:0033365 protein localization to organelle; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0006412 translation; GO:0016072 rRNA metabolic process; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0072657 protein localization to membrane; GO:0043043 peptide biosynthetic process; GO:0042254 ribosome biogenesis; GO:1901360 organic cyclic compound metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032774 RNA biosynthetic process; GO:0045047 protein targeting to ER; GO:0043603 cellular amide metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0006401 RNA catabolic process; GO:0016070 RNA metabolic process; GO:0019439 aromatic compound catabolic process; GO:1901575 organic substance catabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0019083 viral transcription; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0046907 intracellular transport; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0044267 cellular protein metabolic process; GO:0006613 cotranslational protein targeting to membrane; GO:0048519 negative regulation of biological process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0016032 viral process; GO:0019080 viral gene expression; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0006886 intracellular protein transport; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0034613 cellular protein localization; GO:0009059 macromolecule biosynthetic process; GO:0090150 establishment of protein localization to membrane; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0051179 localization; GO:0009056 catabolic process; GO:0034660 ncRNA metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0005925 focal adhesion; GO:0070013 intracellular organelle lumen; GO:0044391 ribosomal subunit; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030055 cell-substrate junction; GO:0044445 cytosolic part; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0022626 cytosolic ribosome; GO:0043229 intracellular organelle; GO:0005840 ribosome; GO:0043232 intracellular non-membrane-bounded organelle; GO:0022625 cytosolic large ribosomal subunit; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0015934 large ribosomal subunit; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0005198 structural molecule activity; GO:0003735 structural constituent of ribosome; ","K02930","RP-L4e; large subunit ribosomal protein L4e","hsa03010 Ribosome - Homo sapiens (human); ","IPR023574; IPR025755; ","\"Ribosomal protein L4 domain; 60S ribosomal protein L4, C-terminal domain; \"\r"]
["P36873","Serine/threonine-protein phosphatase PP1-gamma catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CC","PPP1CC",36.983,4.3114,31.6,8,17,1,1.049,1.004,0.821,1.175,0.906,1.058,1.092,0.456,"cytoplasm\r","GO:0048869 cellular developmental process; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0044264 cellular polysaccharide metabolic process; GO:0043153 entrainment of circadian clock by photoperiod; GO:0009605 response to external stimulus; GO:0000819 sister chromatid segregation; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0044262 cellular carbohydrate metabolic process; GO:0032879 regulation of localization; GO:0042752 regulation of circadian rhythm; GO:0009314 response to radiation; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0010468 regulation of gene expression; GO:0007059 chromosome segregation; GO:0006073 cellular glucan metabolic process; GO:0048699 generation of neurons; GO:0055114 oxidation-reduction process; GO:0044763 single-organism cellular process; GO:0032386 regulation of intracellular transport; GO:0005975 carbohydrate metabolic process; GO:0032501 multicellular organismal process; GO:0007623 circadian rhythm; GO:1902589 single-organism organelle organization; GO:0044723 single-organism carbohydrate metabolic process; GO:0050789 regulation of biological process; GO:0009649 entrainment of circadian clock; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006464 cellular protein modification process; GO:0051301 cell division; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0009628 response to abiotic stimulus; GO:0060255 regulation of macromolecule metabolic process; GO:0044042 glucan metabolic process; GO:0044267 cellular protein metabolic process; GO:0009648 photoperiodism; GO:0006112 energy reserve metabolic process; GO:0050896 response to stimulus; GO:0060341 regulation of cellular localization; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0005976 polysaccharide metabolic process; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0009416 response to light stimulus; GO:0048731 system development; GO:0051049 regulation of transport; GO:0005977 glycogen metabolic process; GO:0044238 primary metabolic process; GO:0006470 protein dephosphorylation; GO:0016311 dephosphorylation; GO:0032922 circadian regulation of gene expression; GO:0030182 neuron differentiation; GO:0051276 chromosome organization; GO:0046822 regulation of nucleocytoplasmic transport; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0098813 nuclear chromosome segregation; GO:0048511 rhythmic process; GO:0044767 single-organism developmental process; GO:0022402 cell cycle process; GO:0007062 sister chromatid cohesion; GO:0043412 macromolecule modification; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0030425 dendrite; GO:0019867 outer membrane; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0008287 protein serine/threonine phosphatase complex; GO:0005623 cell; GO:0032155 cell division site part; GO:0044422 organelle part; GO:0043197 dendritic spine; GO:0043228 non-membrane-bounded organelle; GO:0000793 condensed chromosome; GO:0005654 nucleoplasm; GO:0005925 focal adhesion; GO:0016607 nuclear speck; GO:0005622 intracellular; GO:0043005 neuron projection; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0044451 nucleoplasm part; GO:0000776 kinetochore; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0042995 cell projection; GO:0000779 condensed chromosome, centromeric region; GO:0031967 organelle envelope; GO:0030496 midbody; GO:0070161 anchoring junction; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0098794 postsynapse; GO:0031975 envelope; GO:0043234 protein complex; GO:0031966 mitochondrial membrane; GO:0030054 cell junction; GO:0044424 intracellular part; GO:0072357 PTW/PP1 phosphatase complex; GO:0016604 nuclear body; GO:1903293 phosphatase complex; GO:0000777 condensed chromosome kinetochore; GO:0044427 chromosomal part; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0044309 neuron spine; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005694 chromosome; GO:0005912 adherens junction; GO:0031968 organelle outer membrane; GO:0032154 cleavage furrow; GO:0044456 synapse part; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0044429 mitochondrial part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0097610 cell surface furrow; GO:0005741 mitochondrial outer membrane; GO:0044446 intracellular organelle part; GO:0032153 cell division site; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0045202 synapse; GO:0098687 chromosomal region; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0005634 nucleus; GO:0000775 chromosome, centromeric region; GO:0009986 cell surface; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0003723 RNA binding; GO:0047485 protein N-terminus binding; GO:0019903 protein phosphatase binding; GO:0004722 protein serine/threonine phosphatase activity; GO:0005521 lamin binding; GO:0016791 phosphatase activity; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0019901 protein kinase binding; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0004721 phosphoprotein phosphatase activity; GO:0019900 kinase binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0042578 phosphoric ester hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0019904 protein domain specific binding; GO:0008022 protein C-terminus binding; GO:0019902 phosphatase binding; GO:0019899 enzyme binding; GO:0032403 protein complex binding; GO:0008157 protein phosphatase 1 binding; ","K06269","PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]","hsa04921 Oxytocin signaling pathway - Homo sapiens (human); hsa04728 Dopaminergic synapse - Homo sapiens (human); hsa04218 Cellular senescence - Homo sapiens (human); hsa05168 Herpes simplex infection - Homo sapiens (human); hsa05031 Amphetamine addiction - Homo sapiens (human); hsa04910 Insulin signaling pathway - Homo sapiens (human); hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human); hsa04270 Vascular smooth muscle contraction - Homo sapiens (human); hsa04024 cAMP signaling pathway - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa03015 mRNA surveillance pathway - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa04750 Inflammatory mediator regulation of TRP channels - Homo sapiens (human); hsa04931 Insulin resistance - Homo sapiens (human); hsa04114 Oocyte meiosis - Homo sapiens (human); hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa04390 Hippo signaling pathway - Homo sapiens (human); hsa04611 Platelet activation - Homo sapiens (human); hsa05034 Alcoholism - Homo sapiens (human); hsa04720 Long-term potentiation - Homo sapiens (human); ","IPR029052; IPR004843; IPR031675; IPR006186; ","\"Metallo-dependent phosphatase-like; Calcineurin-like phosphoesterase domain, ApaH type; Serine-threonine protein phosphatase, N-terminal; Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase; \"\r"]
["P36952","Serpin B5 OS=Homo sapiens OX=9606 GN=SERPINB5","SERPINB5",42.1,235.96,59.5,18,56,18,0.935,0.902,0.912,1.097,1.086,1.067,1.182,0.000237,"cytoplasm\r","GO:0048732 gland development; GO:0022414 reproductive process; GO:0044699 single-organism process; GO:0010466 negative regulation of peptidase activity; GO:0048729 tissue morphogenesis; GO:0050678 regulation of epithelial cell proliferation; GO:0044702 single organism reproductive process; GO:0030198 extracellular matrix organization; GO:0032502 developmental process; GO:0052548 regulation of endopeptidase activity; GO:0060429 epithelium development; GO:0003006 developmental process involved in reproduction; GO:0009888 tissue development; GO:0080090 regulation of primary metabolic process; GO:0048608 reproductive structure development; GO:0044763 single-organism cellular process; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0048513 animal organ development; GO:0001655 urogenital system development; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0009887 animal organ morphogenesis; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0052547 regulation of peptidase activity; GO:0048856 anatomical structure development; GO:0050794 regulation of cellular process; GO:0000003 reproduction; GO:0002009 morphogenesis of an epithelium; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0010951 negative regulation of endopeptidase activity; GO:0042127 regulation of cell proliferation; GO:0060255 regulation of macromolecule metabolic process; GO:0030850 prostate gland development; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0051346 negative regulation of hydrolase activity; GO:0060512 prostate gland morphogenesis; GO:0009653 anatomical structure morphogenesis; GO:0043062 extracellular structure organization; GO:0007275 multicellular organism development; GO:0061458 reproductive system development; GO:0009987 cellular process; GO:0045861 negative regulation of proteolysis; GO:0048731 system development; GO:0030162 regulation of proteolysis; GO:0009892 negative regulation of metabolic process; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0051248 negative regulation of protein metabolic process; GO:0006928 movement of cell or subcellular component; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; GO:0022612 gland morphogenesis; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:0004867 serine-type endopeptidase inhibitor activity; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0030414 peptidase inhibitor activity; GO:0061134 peptidase regulator activity; GO:0005515 protein binding; GO:0061135 endopeptidase regulator activity; GO:0098772 molecular function regulator; GO:0004857 enzyme inhibitor activity; GO:0004866 endopeptidase inhibitor activity; ","K10139","SERPINB5; serpin B5","hsa05206 MicroRNAs in cancer - Homo sapiens (human); hsa04115 p53 signaling pathway - Homo sapiens (human); ","IPR033836; IPR023796; ","Maspin; Serpin domain; \r"]
["P36957","Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLST","DLST",48.755,74.286,27.4,12,27,12,1.057,1.066,1.035,0.982,0.938,0.939,0.905,0.00468,"mitochondria\r","GO:1901606 alpha-amino acid catabolic process; GO:0009066 aspartate family amino acid metabolic process; GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine; GO:0044699 single-organism process; GO:0046440 L-lysine metabolic process; GO:0044237 cellular metabolic process; GO:0019474 L-lysine catabolic process to acetyl-CoA; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0032787 monocarboxylic acid metabolic process; GO:0044248 cellular catabolic process; GO:0046487 glyoxylate metabolic process; GO:0009987 cellular process; GO:0006790 sulfur compound metabolic process; GO:0072350 tricarboxylic acid metabolic process; GO:0055114 oxidation-reduction process; GO:0044712 single-organism catabolic process; GO:0044281 small molecule metabolic process; GO:0006099 tricarboxylic acid cycle; GO:0044763 single-organism cellular process; GO:0035383 thioester metabolic process; GO:0006553 lysine metabolic process; GO:0006081 cellular aldehyde metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0006732 coenzyme metabolic process; GO:0044282 small molecule catabolic process; GO:0006084 acetyl-CoA metabolic process; GO:1901605 alpha-amino acid metabolic process; GO:0044238 primary metabolic process; GO:0045333 cellular respiration; GO:0006637 acyl-CoA metabolic process; GO:0051186 cofactor metabolic process; GO:0046395 carboxylic acid catabolic process; GO:0006101 citrate metabolic process; GO:1901575 organic substance catabolic process; GO:0009068 aspartate family amino acid catabolic process; GO:1901565 organonitrogen compound catabolic process; GO:0019477 L-lysine catabolic process; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0009060 aerobic respiration; GO:0015980 energy derivation by oxidation of organic compounds; GO:0016054 organic acid catabolic process; GO:0019752 carboxylic acid metabolic process; GO:0009063 cellular amino acid catabolic process; GO:0006554 lysine catabolic process; GO:0006082 organic acid metabolic process; GO:0009056 catabolic process; GO:0043436 oxoacid metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0045240 dihydrolipoyl dehydrogenase complex; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0043209 myelin sheath; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005759 mitochondrial matrix; GO:0044429 mitochondrial part; GO:0044446 intracellular organelle part; GO:1990234 transferase complex; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:1990204 oxidoreductase complex; GO:0045252 oxoglutarate dehydrogenase complex; GO:0043234 protein complex; GO:0045239 tricarboxylic acid cycle enzyme complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016417 S-acyltransferase activity; GO:0016751 S-succinyltransferase activity; GO:0016746 transferase activity, transferring acyl groups; GO:0004149 dihydrolipoyllysine-residue succinyltransferase activity; GO:0003824 catalytic activity; GO:0016748 succinyltransferase activity; GO:0016740 transferase activity; GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups; ","K00658","DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]","hsa00310 Lysine degradation - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00020 Citrate cycle (TCA cycle) - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); ","IPR001078; IPR011053; IPR000089; IPR023213; ","\"2-oxoacid dehydrogenase acyltransferase, catalytic domain; Single hybrid motif; Biotin/lipoyl attachment; Chloramphenicol acetyltransferase-like domain; \"\r"]
["P36969","Phospholipid hydroperoxide glutathione peroxidase OS=Homo sapiens OX=9606 GN=GPX4","GPX4",22.174,26.924,34.5,6,6,6,1.166,1.042,1.086,0.831,0.932,0.894,0.807,0.0102,"extracellular\r","GO:0044707 single-multicellular organism process; GO:1901568 fatty acid derivative metabolic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:1990748 cellular detoxification; GO:0006979 response to oxidative stress; GO:0032787 monocarboxylic acid metabolic process; GO:0019372 lipoxygenase pathway; GO:0098869 cellular oxidant detoxification; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0006690 icosanoid metabolic process; GO:0006629 lipid metabolic process; GO:0032502 developmental process; GO:0006950 response to stress; GO:0055114 oxidation-reduction process; GO:0009636 response to toxic substance; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006631 fatty acid metabolic process; GO:0044238 primary metabolic process; GO:0032501 multicellular organismal process; GO:0042221 response to chemical; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0044767 single-organism developmental process; GO:0019752 carboxylic acid metabolic process; GO:0019637 organophosphate metabolic process; GO:0006644 phospholipid metabolic process; GO:0006082 organic acid metabolic process; GO:0098754 detoxification; GO:0048856 anatomical structure development; GO:0043436 oxoacid metabolic process; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0004602 glutathione peroxidase activity; GO:0003824 catalytic activity; GO:0016209 antioxidant activity; GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity; GO:0004601 peroxidase activity; GO:0016684 oxidoreductase activity, acting on peroxide as acceptor; GO:0016491 oxidoreductase activity; ","K05361","GPX4; phospholipid-hydroperoxide glutathione peroxidase [EC:1.11.1.12]","hsa00480 Glutathione metabolism - Homo sapiens (human); hsa04216 Ferroptosis - Homo sapiens (human); ","IPR012336; ","Thioredoxin-like fold; \r"]
["P37235","Hippocalcin-like protein 1 OS=Homo sapiens OX=9606 GN=HPCAL1","HPCAL1",22.313,9.7888,28,6,7,2,0.872,0.925,1.062,0.955,1.211,0.97,1.097,0.404,"cytoplasm\r",null,"GO:0016020 membrane; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0005509 calcium ion binding; GO:0005488 binding; GO:0043167 ion binding; ",{"$nulls":3},"IPR002048; IPR011992; ","EF-hand domain; EF-hand domain pair; \r"]
["P37837","Transaldolase OS=Homo sapiens OX=9606 GN=TALDO1","TALDO1",37.54,89.147,42.7,17,44,17,0.996,0.969,1.005,1.019,1.034,0.99,1.025,0.223,"mitochondria\r","GO:0006739 NADP metabolic process; GO:0016051 carbohydrate biosynthetic process; GO:0019362 pyridine nucleotide metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0046496 nicotinamide nucleotide metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0006002 fructose 6-phosphate metabolic process; GO:0009058 biosynthetic process; GO:0046364 monosaccharide biosynthetic process; GO:0072524 pyridine-containing compound metabolic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0051156 glucose 6-phosphate metabolic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0019682 glyceraldehyde-3-phosphate metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0005996 monosaccharide metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0006098 pentose-phosphate shunt; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0019321 pentose metabolic process; GO:0019322 pentose biosynthetic process; GO:0005999 xylulose biosynthetic process; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0044711 single-organism biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0006081 cellular aldehyde metabolic process; GO:0006732 coenzyme metabolic process; GO:0009052 pentose-phosphate shunt, non-oxidative branch; GO:0005975 carbohydrate metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0051186 cofactor metabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0044283 small molecule biosynthetic process; GO:0005997 xylulose metabolic process; GO:0019637 organophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0004801 sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016744 transferase activity, transferring aldehyde or ketonic groups; GO:0030246 carbohydrate binding; GO:0005515 protein binding; GO:0048029 monosaccharide binding; GO:0016740 transferase activity; GO:0036094 small molecule binding; ","K00616","E2.2.1.2; transaldolase [EC:2.2.1.2]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00030 Pentose phosphate pathway - Homo sapiens (human); hsa01230 Biosynthesis of amino acids - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); ","IPR013785; ","Aldolase-type TIM barrel; \r"]
["P38159","RNA-binding motif protein, X chromosome OS=Homo sapiens OX=9606 GN=RBMX","RBMX",42.331,44.782,11,4,9,2,0.94,0.942,0.929,1.012,1.132,1.043,1.134,0.0663,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0001649 osteoblast differentiation; GO:0022613 ribonucleoprotein complex biogenesis; GO:0000381 regulation of alternative mRNA splicing, via spliceosome; GO:0022618 ribonucleoprotein complex assembly; GO:0097659 nucleic acid-templated transcription; GO:0009891 positive regulation of biosynthetic process; GO:0050686 negative regulation of mRNA processing; GO:0070555 response to interleukin-1; GO:0071345 cellular response to cytokine stimulus; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0065003 macromolecular complex assembly; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0006396 RNA processing; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0001503 ossification; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044763 single-organism cellular process; GO:0032774 RNA biosynthetic process; GO:0050684 regulation of mRNA processing; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0033119 negative regulation of RNA splicing; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0033120 positive regulation of RNA splicing; GO:0006509 membrane protein ectodomain proteolysis; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0051260 protein homooligomerization; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0051259 protein oligomerization; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0000375 RNA splicing, via transesterification reactions; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0008380 RNA splicing; GO:0006461 protein complex assembly; GO:0051254 positive regulation of RNA metabolic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0043484 regulation of RNA splicing; GO:1903311 regulation of mRNA metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0048025 negative regulation of mRNA splicing, via spliceosome; GO:0000245 spliceosomal complex assembly; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0033619 membrane protein proteolysis; GO:0051253 negative regulation of RNA metabolic process; GO:1903312 negative regulation of mRNA metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0071826 ribonucleoprotein complex subunit organization; GO:0022607 cellular component assembly; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0048024 regulation of mRNA splicing, via spliceosome; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0071822 protein complex subunit organization; GO:0034097 response to cytokine; GO:0031326 regulation of cellular biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0010605 negative regulation of macromolecule metabolic process; GO:1903313 positive regulation of mRNA metabolic process; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0019222 regulation of metabolic process; GO:0070271 protein complex biogenesis; GO:0006376 mRNA splice site selection; GO:0016043 cellular component organization; GO:0050685 positive regulation of mRNA processing; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0071310 cellular response to organic substance; GO:0071347 cellular response to interleukin-1; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0000398 mRNA splicing, via spliceosome; GO:0034641 cellular nitrogen compound metabolic process; GO:0006508 proteolysis; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0034622 cellular macromolecular complex assembly; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0006807 nitrogen compound metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044767 single-organism developmental process; GO:0006366 transcription from RNA polymerase II promoter; GO:0048026 positive regulation of mRNA splicing, via spliceosome; GO:0010467 gene expression; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044454 nuclear chromosome part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0000790 nuclear chromatin; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0000791 euchromatin; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005681 spliceosomal complex; GO:0005576 extracellular region; GO:0044530 supraspliceosomal complex; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0000785 chromatin; GO:0071013 catalytic step 2 spliceosome; GO:0000228 nuclear chromosome; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0005719 nuclear euchromatin; GO:0043230 extracellular organelle; GO:0044428 nuclear part; ","GO:0003723 RNA binding; GO:0003677 DNA binding; GO:1901265 nucleoside phosphate binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0003682 chromatin binding; GO:0003727 single-stranded RNA binding; GO:0001047 core promoter binding; GO:1901363 heterocyclic compound binding; GO:0000975 regulatory region DNA binding; GO:0097159 organic cyclic compound binding; GO:0003729 mRNA binding; GO:0001067 regulatory region nucleic acid binding; GO:0042802 identical protein binding; GO:0005488 binding; GO:0044212 transcription regulatory region DNA binding; GO:0003676 nucleic acid binding; GO:0036094 small molecule binding; ","K12885","RBMX; heterogeneous nuclear ribonucleoprotein G","hsa03040 Spliceosome - Homo sapiens (human); ","IPR000504; IPR012604; IPR012677; IPR003954; ","\"RNA recognition motif domain; RBM1CTR; Nucleotide-binding alpha-beta plait domain; RNA recognition motif domain, eukaryote; \"\r"]
["P38606","V-type proton ATPase catalytic subunit A OS=Homo sapiens OX=9606 GN=ATP6V1A","ATP6V1A",68.303,113.86,38.1,22,29,22,0.971,0.971,0.974,1.01,1.048,1.009,1.052,0.0567,"cytoplasm\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0009116 nucleoside metabolic process; GO:0007166 cell surface receptor signaling pathway; GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient; GO:0030641 regulation of cellular pH; GO:0030004 cellular monovalent inorganic cation homeostasis; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0000041 transition metal ion transport; GO:0008152 metabolic process; GO:0009719 response to endogenous stimulus; GO:0019693 ribose phosphate metabolic process; GO:0008104 protein localization; GO:1901652 response to peptide; GO:0044765 single-organism transport; GO:0051716 cellular response to stimulus; GO:0090383 phagosome acidification; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0033572 transferrin transport; GO:0010506 regulation of autophagy; GO:0016241 regulation of macroautophagy; GO:0006810 transport; GO:0010243 response to organonitrogen compound; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:1901698 response to nitrogen compound; GO:0032869 cellular response to insulin stimulus; GO:0009126 purine nucleoside monophosphate metabolic process; GO:0098662 inorganic cation transmembrane transport; GO:0050794 regulation of cellular process; GO:0034220 ion transmembrane transport; GO:0006885 regulation of pH; GO:0030001 metal ion transport; GO:0009259 ribonucleotide metabolic process; GO:1901700 response to oxygen-containing compound; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0099131 ATP hydrolysis coupled ion transmembrane transport; GO:0009119 ribonucleoside metabolic process; GO:0048878 chemical homeostasis; GO:0071702 organic substance transport; GO:0009141 nucleoside triphosphate metabolic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0006163 purine nucleotide metabolic process; GO:0045184 establishment of protein localization; GO:0072512 trivalent inorganic cation transport; GO:0055085 transmembrane transport; GO:0006873 cellular ion homeostasis; GO:0051453 regulation of intracellular pH; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0006811 ion transport; GO:0019637 organophosphate metabolic process; GO:0051179 localization; GO:0015672 monovalent inorganic cation transport; GO:1901564 organonitrogen compound metabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0008286 insulin receptor signaling pathway; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0090662 ATP hydrolysis coupled transmembrane transport; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:1901653 cellular response to peptide; GO:0007154 cell communication; GO:0006753 nucleoside phosphate metabolic process; GO:0033036 macromolecule localization; GO:0070887 cellular response to chemical stimulus; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0098655 cation transmembrane transport; GO:0050801 ion homeostasis; GO:0015682 ferric iron transport; GO:0098771 inorganic ion homeostasis; GO:1901360 organic cyclic compound metabolic process; GO:0019725 cellular homeostasis; GO:0023052 signaling; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0071417 cellular response to organonitrogen compound; GO:0050789 regulation of biological process; GO:0032868 response to insulin; GO:0042221 response to chemical; GO:0043434 response to peptide hormone; GO:1901699 cellular response to nitrogen compound; GO:0032870 cellular response to hormone stimulus; GO:0019222 regulation of metabolic process; GO:0015991 ATP hydrolysis coupled proton transport; GO:1901657 glycosyl compound metabolic process; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0045851 pH reduction; GO:0071310 cellular response to organic substance; GO:0030003 cellular cation homeostasis; GO:0006826 iron ion transport; GO:0050896 response to stimulus; GO:0055082 cellular chemical homeostasis; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0055080 cation homeostasis; GO:0006812 cation transport; GO:0071375 cellular response to peptide hormone stimulus; GO:1902600 hydrogen ion transmembrane transport; GO:0034641 cellular nitrogen compound metabolic process; GO:0099132 ATP hydrolysis coupled cation transmembrane transport; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0009987 cellular process; GO:0046034 ATP metabolic process; GO:0090382 phagosome maturation; GO:0055067 monovalent inorganic cation homeostasis; GO:0098660 inorganic ion transmembrane transport; GO:0006807 nitrogen compound metabolic process; GO:0015992 proton transport; GO:0006818 hydrogen transport; GO:0046128 purine ribonucleoside metabolic process; GO:1901701 cellular response to oxygen-containing compound; GO:0071495 cellular response to endogenous stimulus; GO:0009150 purine ribonucleotide metabolic process; GO:0051452 intracellular pH reduction; GO:0009725 response to hormone; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0016324 apical plasma membrane; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0033176 proton-transporting V-type ATPase complex; GO:0005887 integral component of plasma membrane; GO:0098858 actin-based cell projection; GO:0005623 cell; GO:0044422 organelle part; GO:0005765 lysosomal membrane; GO:0070062 extracellular exosome; GO:0098590 plasma membrane region; GO:0043209 myelin sheath; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0098805 whole membrane; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0045177 apical part of cell; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0031226 intrinsic component of plasma membrane; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0033180 proton-transporting V-type ATPase, V1 domain; GO:0098852 lytic vacuole membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0044437 vacuolar part; GO:0016469 proton-transporting two-sector ATPase complex; GO:0005902 microvillus; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0042625 ATPase coupled ion transmembrane transporter activity; GO:1901265 nucleoside phosphate binding; GO:0015399 primary active transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism; GO:0015077 monovalent inorganic cation transmembrane transporter activity; GO:0016787 hydrolase activity; GO:0015078 hydrogen ion transmembrane transporter activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0016887 ATPase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0019829 cation-transporting ATPase activity; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0043492 ATPase activity, coupled to movement of substances; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0036442 hydrogen-exporting ATPase activity; GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0022890 inorganic cation transmembrane transporter activity; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005215 transporter activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0022804 active transmembrane transporter activity; GO:0005524 ATP binding; GO:0015075 ion transmembrane transporter activity; GO:0022853 active ion transmembrane transporter activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0046961 proton-transporting ATPase activity, rotational mechanism; GO:0032549 ribonucleoside binding; GO:0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity; GO:0097367 carbohydrate derivative binding; GO:0042626 ATPase activity, coupled to transmembrane movement of substances; GO:0042623 ATPase activity, coupled; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0008324 cation transmembrane transporter activity; GO:0022857 transmembrane transporter activity; GO:0036094 small molecule binding; ","K02145","ATPeV1A; V-type H+-transporting ATPase subunit A [EC:3.6.3.14]","hsa05120 Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human); hsa04966 Collecting duct acid secretion - Homo sapiens (human); hsa05323 Rheumatoid arthritis - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa04150 mTOR signaling pathway - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05110 Vibrio cholerae infection - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); hsa04721 Synaptic vesicle cycle - Homo sapiens (human); ","IPR031686; IPR004100; IPR000194; IPR027417; IPR024034; ","\"ATPsynthase alpha/beta subunit, N-terminal extension; ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain; ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain; P-loop containing nucleoside triphosphate hydrolase; ATPase, F1/V1 complex, beta subunit, C-terminal; \"\r"]
["P39023","60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3","RPL3",46.108,82.311,38.5,16,29,16,0.814,0.855,0.865,1.141,1.166,1.151,1.365,9.65e-05,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0072594 establishment of protein localization to organelle; GO:0006518 peptide metabolic process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0071345 cellular response to cytokine stimulus; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0051649 establishment of localization in cell; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0070972 protein localization to endoplasmic reticulum; GO:0006364 rRNA processing; GO:0006413 translational initiation; GO:1901361 organic cyclic compound catabolic process; GO:0033365 protein localization to organelle; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0006412 translation; GO:0070887 cellular response to chemical stimulus; GO:0016072 rRNA metabolic process; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0051716 cellular response to stimulus; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0072657 protein localization to membrane; GO:0034097 response to cytokine; GO:0043043 peptide biosynthetic process; GO:0042254 ribosome biogenesis; GO:1901360 organic cyclic compound metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032774 RNA biosynthetic process; GO:0045047 protein targeting to ER; GO:0043603 cellular amide metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0071353 cellular response to interleukin-4; GO:0051704 multi-organism process; GO:0006810 transport; GO:0016070 RNA metabolic process; GO:0006401 RNA catabolic process; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0090304 nucleic acid metabolic process; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0019083 viral transcription; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0046907 intracellular transport; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0071310 cellular response to organic substance; GO:0044267 cellular protein metabolic process; GO:0006613 cotranslational protein targeting to membrane; GO:0048519 negative regulation of biological process; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0016032 viral process; GO:0019080 viral gene expression; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0006886 intracellular protein transport; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0034613 cellular protein localization; GO:0009059 macromolecule biosynthetic process; GO:0090150 establishment of protein localization to membrane; GO:0070670 response to interleukin-4; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0051179 localization; GO:0009056 catabolic process; GO:0034660 ncRNA metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0044421 extracellular region part; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0005925 focal adhesion; GO:0070013 intracellular organelle lumen; GO:0044391 ribosomal subunit; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030055 cell-substrate junction; GO:0044445 cytosolic part; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0022626 cytosolic ribosome; GO:0043229 intracellular organelle; GO:0005840 ribosome; GO:0043232 intracellular non-membrane-bounded organelle; GO:0022625 cytosolic large ribosomal subunit; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0015934 large ribosomal subunit; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0008097 5S rRNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0005198 structural molecule activity; GO:0003735 structural constituent of ribosome; GO:0019843 rRNA binding; ","K02925","RP-L3e; large subunit ribosomal protein L3e","hsa03010 Ribosome - Homo sapiens (human); ","IPR009000; ","\"Translation protein, beta-barrel domain; \"\r"]
["P39059","Collagen alpha-1(XV) chain OS=Homo sapiens OX=9606 GN=COL15A1","COL15A1",141.72,59.15,6.8,8,9,8,1.076,1.232,1.07,0.84,0.962,0.878,0.793,0.0193,"mitochondria\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0072359 circulatory system development; GO:0044707 single-multicellular organism process; GO:0001568 blood vessel development; GO:0048869 cellular developmental process; GO:0044236 multicellular organism metabolic process; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0022610 biological adhesion; GO:0009653 anatomical structure morphogenesis; GO:0008152 metabolic process; GO:0044243 multicellular organismal catabolic process; GO:0030154 cell differentiation; GO:0007165 signal transduction; GO:0001525 angiogenesis; GO:0007154 cell communication; GO:0007155 cell adhesion; GO:0043170 macromolecule metabolic process; GO:0048514 blood vessel morphogenesis; GO:0007275 multicellular organism development; GO:0044259 multicellular organismal macromolecule metabolic process; GO:0009987 cellular process; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0030574 collagen catabolic process; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0044712 single-organism catabolic process; GO:0048731 system development; GO:0044763 single-organism cellular process; GO:0001944 vasculature development; GO:0072358 cardiovascular system development; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0050789 regulation of biological process; GO:0044710 single-organism metabolic process; GO:0044767 single-organism developmental process; GO:0032963 collagen metabolic process; GO:0009056 catabolic process; GO:0048856 anatomical structure development; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044420 extracellular matrix component; GO:0005581 collagen trimer; GO:0044422 organelle part; GO:0005604 basement membrane; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005788 endoplasmic reticulum lumen; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005582 collagen type XV trimer; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031012 extracellular matrix; GO:0044432 endoplasmic reticulum part; GO:0098651 basement membrane collagen trimer; GO:0005578 proteinaceous extracellular matrix; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005201 extracellular matrix structural constituent; GO:0005198 structural molecule activity; ","K08135","COL15A; collagen, type XV, alpha","hsa04974 Protein digestion and absorption - Homo sapiens (human); ","IPR010515; IPR016187; IPR001791; IPR013320; IPR016186; ","Collagenase NC10/endostatin; C-type lectin fold; Laminin G domain; Concanavalin A-like lectin/glucanase domain; C-type lectin-like/link domain; \r"]
["P39656","Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST","DDOST",50.8,62.642,29.4,11,26,11,1.056,0.996,1.034,1.018,0.985,0.951,0.957,0.168,"plasma membrane\r","GO:0043413 macromolecule glycosylation; GO:0045321 leukocyte activation; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0018196 peptidyl-asparagine modification; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:0042110 T cell activation; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006487 protein N-linked glycosylation; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0006486 protein glycosylation; GO:0002443 leukocyte mediated immunity; GO:0009101 glycoprotein biosynthetic process; GO:0034097 response to cytokine; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0009100 glycoprotein metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0006810 transport; GO:0042221 response to chemical; GO:0032940 secretion by cell; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0043299 leukocyte degranulation; GO:0036211 protein modification process; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0044267 cellular protein metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:1901135 carbohydrate derivative metabolic process; GO:0036230 granulocyte activation; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0070085 glycosylation; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0046649 lymphocyte activation; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0043312 neutrophil degranulation; GO:1901576 organic substance biosynthetic process; GO:0002263 cell activation involved in immune response; GO:0044249 cellular biosynthetic process; GO:0002366 leukocyte activation involved in immune response; GO:0018193 peptidyl-amino acid modification; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0018279 protein N-linked glycosylation via asparagine; GO:0034645 cellular macromolecule biosynthetic process; GO:0001775 cell activation; GO:0043412 macromolecule modification; GO:0006955 immune response; GO:0051179 localization; GO:0006887 exocytosis; ","GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0031224 intrinsic component of membrane; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005765 lysosomal membrane; GO:1902494 catalytic complex; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0035577 azurophil granule membrane; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0008250 oligosaccharyltransferase complex; GO:1990234 transferase complex; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0042582 azurophil granule; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0030667 secretory granule membrane; GO:0044432 endoplasmic reticulum part; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0016757 transferase activity, transferring glycosyl groups; GO:0005515 protein binding; GO:0003824 catalytic activity; GO:0016740 transferase activity; GO:0005488 binding; ","K12670","WBP1; oligosaccharyltransferase complex subunit beta","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00510 N-Glycan biosynthesis - Homo sapiens (human); hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); "]
["P39748","Flap endonuclease 1 OS=Homo sapiens OX=9606 GN=FEN1","FEN1",42.592,16.992,14.5,4,4,4,0.82,0.684,0.788,1.181,1.243,1.259,1.607,0.00122,"nucleus\r","GO:0065008 regulation of biological quality; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0050877 neurological system process; GO:0051130 positive regulation of cellular component organization; GO:0007610 behavior; GO:0008152 metabolic process; GO:1901361 organic cyclic compound catabolic process; GO:0009314 response to radiation; GO:0043170 macromolecule metabolic process; GO:0090068 positive regulation of cell cycle process; GO:0006261 DNA-dependent DNA replication; GO:0051726 regulation of cell cycle; GO:0006310 DNA recombination; GO:0051716 cellular response to stimulus; GO:0033045 regulation of sister chromatid segregation; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0032501 multicellular organismal process; GO:0022616 DNA strand elongation; GO:0009650 UV protection; GO:0000722 telomere maintenance via recombination; GO:0006401 RNA catabolic process; GO:0016070 RNA metabolic process; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0010638 positive regulation of organelle organization; GO:0006271 DNA strand elongation involved in DNA replication; GO:2001252 positive regulation of chromosome organization; GO:0044260 cellular macromolecule metabolic process; GO:0007613 memory; GO:0006273 lagging strand elongation; GO:0032200 telomere organization; GO:0090305 nucleic acid phosphodiester bond hydrolysis; GO:0006312 mitotic recombination; GO:0045876 positive regulation of sister chromatid cohesion; GO:0044708 single-organism behavior; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0033554 cellular response to stress; GO:0016043 cellular component organization; GO:0006260 DNA replication; GO:0006725 cellular aromatic compound metabolic process; GO:0009628 response to abiotic stimulus; GO:0006259 DNA metabolic process; GO:0006302 double-strand break repair; GO:0050896 response to stimulus; GO:0060249 anatomical structure homeostasis; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0042592 homeostatic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0050890 cognition; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0051984 positive regulation of chromosome segregation; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0000724 double-strand break repair via homologous recombination; GO:0045787 positive regulation of cell cycle; GO:0051983 regulation of chromosome segregation; GO:0044265 cellular macromolecule catabolic process; GO:0003008 system process; GO:0009416 response to light stimulus; GO:0006950 response to stress; GO:0007063 regulation of sister chromatid cohesion; GO:0033043 regulation of organelle organization; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:1901576 organic substance biosynthetic process; GO:0033044 regulation of chromosome organization; GO:0007611 learning or memory; GO:0006974 cellular response to DNA damage stimulus; GO:0044249 cellular biosynthetic process; GO:0043137 DNA replication, removal of RNA primer; GO:0033567 DNA replication, Okazaki fragment processing; GO:0090501 RNA phosphodiester bond hydrolysis; GO:0000725 recombinational repair; GO:0006281 DNA repair; GO:0009411 response to UV; GO:0034645 cellular macromolecule biosynthetic process; GO:0051276 chromosome organization; GO:0006996 organelle organization; GO:0009057 macromolecule catabolic process; GO:0051128 regulation of cellular component organization; GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic; GO:0009056 catabolic process; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; GO:0000723 telomere maintenance; ","GO:0016020 membrane; GO:0000784 nuclear chromosome, telomeric region; GO:0000781 chromosome, telomeric region; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044454 nuclear chromosome part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005739 mitochondrion; GO:0098687 chromosomal region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0000228 nuclear chromosome; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0016895 exodeoxyribonuclease activity, producing 5'-phosphomonoesters; GO:0003690 double-stranded DNA binding; GO:0004521 endoribonuclease activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043169 cation binding; GO:0008409 5'-3' exonuclease activity; GO:0003684 damaged DNA binding; GO:0004540 ribonuclease activity; GO:0004519 endonuclease activity; GO:0003677 DNA binding; GO:0004523 RNA-DNA hybrid ribonuclease activity; GO:0004536 deoxyribonuclease activity; GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters; GO:0004529 exodeoxyribonuclease activity; GO:0008309 double-stranded DNA exodeoxyribonuclease activity; GO:0043167 ion binding; GO:0004520 endodeoxyribonuclease activity; GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters; GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters; GO:0017108 5'-flap endonuclease activity; GO:0016788 hydrolase activity, acting on ester bonds; GO:0004518 nuclease activity; GO:0003676 nucleic acid binding; GO:0004527 exonuclease activity; GO:0046872 metal ion binding; GO:0048256 flap endonuclease activity; ","K04799","FEN1; flap endonuclease-1 [EC:3.-.-.-]","hsa03450 Non-homologous end-joining - Homo sapiens (human); hsa03410 Base excision repair - Homo sapiens (human); hsa03030 DNA replication - Homo sapiens (human); ","IPR006085; IPR020045; IPR029060; IPR006086; ","\"XPG N-terminal; 5'-3' exonuclease, C-terminal domain; PIN domain-like; XPG-I domain; \"\r"]
["P40227","T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A","CCT6A",58.024,35.631,19.2,9,16,9,0.925,0.939,0.853,1.085,1.114,1.095,1.212,3.3E-3,"cytoplasm\r","GO:0065008 regulation of biological quality; GO:0061077 chaperone-mediated protein folding; GO:0009891 positive regulation of biosynthetic process; GO:1904816 positive regulation of protein localization to chromosome, telomeric region; GO:0032204 regulation of telomere maintenance; GO:1904851 positive regulation of establishment of protein localization to telomere; GO:0006457 protein folding; GO:0051130 positive regulation of cellular component organization; GO:0006458 'de novo' protein folding; GO:0009893 positive regulation of metabolic process; GO:0032879 regulation of localization; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0032846 positive regulation of homeostatic process; GO:1904874 positive regulation of telomerase RNA localization to Cajal body; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0051054 positive regulation of DNA metabolic process; GO:0048522 positive regulation of cellular process; GO:0032212 positive regulation of telomere maintenance via telomerase; GO:0031323 regulation of cellular metabolic process; GO:0050789 regulation of biological process; GO:0051052 regulation of DNA metabolic process; GO:0010638 positive regulation of organelle organization; GO:1900180 regulation of protein localization to nucleus; GO:2001252 positive regulation of chromosome organization; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0070202 regulation of establishment of protein localization to chromosome; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0032210 regulation of telomere maintenance via telomerase; GO:0060255 regulation of macromolecule metabolic process; GO:1903829 positive regulation of cellular protein localization; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0032844 regulation of homeostatic process; GO:0070201 regulation of establishment of protein localization; GO:0060341 regulation of cellular localization; GO:1904356 regulation of telomere maintenance via telomere lengthening; GO:0009889 regulation of biosynthetic process; GO:1904871 positive regulation of protein localization to Cajal body; GO:0051171 regulation of nitrogen compound metabolic process; GO:0032880 regulation of protein localization; GO:0009987 cellular process; GO:1904872 regulation of telomerase RNA localization to Cajal body; GO:1904869 regulation of protein localization to Cajal body; GO:1904358 positive regulation of telomere maintenance via telomere lengthening; GO:1904814 regulation of protein localization to chromosome, telomeric region; GO:0033043 regulation of organelle organization; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048518 positive regulation of biological process; GO:2000278 regulation of DNA biosynthetic process; GO:0033044 regulation of chromosome organization; GO:1900182 positive regulation of protein localization to nucleus; GO:1904951 positive regulation of establishment of protein localization; GO:0070203 regulation of establishment of protein localization to telomere; GO:0031325 positive regulation of cellular metabolic process; GO:0032206 positive regulation of telomere maintenance; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0031647 regulation of protein stability; GO:0051128 regulation of cellular component organization; GO:0031328 positive regulation of cellular biosynthetic process; GO:2000573 positive regulation of DNA biosynthetic process; GO:0050821 protein stabilization; GO:1903827 regulation of cellular protein localization; GO:0065007 biological regulation; ","GO:0044421 extracellular region part; GO:0005874 microtubule; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0005623 cell; GO:0099080 supramolecular complex; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005856 cytoskeleton; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0044445 cytosolic part; GO:0043227 membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0005832 chaperonin-containing T-complex; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0099081 supramolecular polymer; GO:0031012 extracellular matrix; GO:0043226 organelle; GO:0101031 chaperone complex; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0003723 RNA binding; GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0044183 protein binding involved in protein folding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0032550 purine ribonucleoside binding; GO:0019904 protein domain specific binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0051082 unfolded protein binding; GO:0071987 WD40-repeat domain binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K09498",null,null,"IPR027410; IPR027409; IPR027413; ","TCP-1-like chaperonin intermediate domain; GroEL-like apical domain; GroEL-like equatorial domain; \r"]
["P40261","Nicotinamide N-methyltransferase OS=Homo sapiens OX=9606 GN=NNMT","NNMT",29.574,16.336,16.7,4,5,4,0.728,0.719,0.73,1.317,1.274,1.207,1.745,2.38e-05,"cytoplasm\r","GO:0051188 cofactor biosynthetic process; GO:0031100 animal organ regeneration; GO:0019362 pyridine nucleotide metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0019363 pyridine nucleotide biosynthetic process; GO:0044237 cellular metabolic process; GO:0072524 pyridine-containing compound metabolic process; GO:0032259 methylation; GO:0006796 phosphate-containing compound metabolic process; GO:0072525 pyridine-containing compound biosynthetic process; GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway; GO:0008152 metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0009719 response to endogenous stimulus; GO:0009108 coenzyme biosynthetic process; GO:0032502 developmental process; GO:0018130 heterocycle biosynthetic process; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0006732 coenzyme metabolic process; GO:0019359 nicotinamide nucleotide biosynthetic process; GO:0032501 multicellular organismal process; GO:0051186 cofactor metabolic process; GO:0090407 organophosphate biosynthetic process; GO:0010243 response to organonitrogen compound; GO:0048513 animal organ development; GO:0042221 response to chemical; GO:0044710 single-organism metabolic process; GO:0019674 NAD metabolic process; GO:1901698 response to nitrogen compound; GO:0048856 anatomical structure development; GO:1901362 organic cyclic compound biosynthetic process; GO:0044707 single-multicellular organism process; GO:0009165 nucleotide biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0046496 nicotinamide nucleotide metabolic process; GO:0050896 response to stimulus; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0042493 response to drug; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0044711 single-organism biosynthetic process; GO:0048731 system development; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0009435 NAD biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0044767 single-organism developmental process; GO:0019637 organophosphate metabolic process; GO:0031099 regeneration; GO:1901564 organonitrogen compound metabolic process; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0044444 cytoplasmic part; ","GO:0030760 pyridine N-methyltransferase activity; GO:0008757 S-adenosylmethionine-dependent methyltransferase activity; GO:0008168 methyltransferase activity; GO:0008112 nicotinamide N-methyltransferase activity; GO:0003824 catalytic activity; GO:0016741 transferase activity, transferring one-carbon groups; GO:0008170 N-methyltransferase activity; GO:0016740 transferase activity; ","K00541","NNMT; nicotinamide N-methyltransferase [EC:2.1.1.1]","hsa00760 Nicotinate and nicotinamide metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR029063; ","S-adenosyl-L-methionine-dependent methyltransferase; \r"]
["P40616","ADP-ribosylation factor-like protein 1 OS=Homo sapiens OX=9606 GN=ARL1","ARL1",20.417,25.944,13.8,3,5,3,0.906,1.102,1.197,0.982,0.966,0.863,0.877,0.242,"extracellular\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0010256 endomembrane system organization; GO:0010517 regulation of phospholipase activity; GO:0048193 Golgi vesicle transport; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0031584 activation of phospholipase D activity; GO:0051345 positive regulation of hydrolase activity; GO:0044093 positive regulation of molecular function; GO:0010518 positive regulation of phospholipase activity; GO:0033365 protein localization to organelle; GO:0016482 cytosolic transport; GO:0034613 cellular protein localization; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0009987 cellular process; GO:0019748 secondary metabolic process; GO:0051716 cellular response to stimulus; GO:0034067 protein localization to Golgi apparatus; GO:0009404 toxin metabolic process; GO:0035556 intracellular signal transduction; GO:0060191 regulation of lipase activity; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0007264 small GTPase mediated signal transduction; GO:0023052 signaling; GO:0043085 positive regulation of catalytic activity; GO:0051641 cellular localization; GO:0060193 positive regulation of lipase activity; GO:0016197 endosomal transport; GO:0006810 transport; GO:0070727 cellular macromolecule localization; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:0042147 retrograde transport, endosome to Golgi; GO:0007030 Golgi organization; GO:0050790 regulation of catalytic activity; GO:0006996 organelle organization; GO:0044710 single-organism metabolic process; GO:0065009 regulation of molecular function; GO:0051179 localization; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0098588 bounding membrane of organelle; GO:0031090 organelle membrane; GO:0031982 vesicle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0032588 trans-Golgi network membrane; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0098791 Golgi subcompartment; GO:0005802 trans-Golgi network; GO:0044431 Golgi apparatus part; GO:0005794 Golgi apparatus; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0031984 organelle subcompartment; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0098772 molecular function regulator; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0003924 GTPase activity; GO:0043169 cation binding; GO:0043168 anion binding; GO:0019001 guanyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005525 GTP binding; GO:0008047 enzyme activator activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0030234 enzyme regulator activity; GO:0046872 metal ion binding; GO:0019904 protein domain specific binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0032561 guanyl ribonucleotide binding; GO:0036094 small molecule binding; ","K07942",null,null,"IPR005225; IPR027417; ","Small GTP-binding protein domain; P-loop containing nucleoside triphosphate hydrolase; \r"]
["P40763","Signal transducer and activator of transcription 3 OS=Homo sapiens OX=9606 GN=STAT3","STAT3",88.067,117.55,24.4,15,21,15,0.867,0.932,0.933,1.076,1.08,1.11,1.195,0.0024,"cyto_nucl\r",{"$cut":{"chars":21958,"head":"GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0045980 negative regulation of nucleotide metabolic process; GO:0022414 reproductive process; GO:0010608 posttranscriptional regulation of gene expression; GO:0002292 T cell differentiation involved in immune response; GO:0042593 glucose homeostasis; GO:0009891 positive regulation of biosynthetic process; GO:0044237 cellular metabolic process; GO:0042110 T cell activation; GO:0045978 negative regulation of nucleoside metabolic process; GO:0008152 metabolic process; GO:0042516 regulation of tyrosine phosphorylation of Stat3 protein; GO:0044093 positive regulation of molecular function; GO:0030522 intracellular receptor signaling pathway; GO:0090559 regulation of membrane permeability; GO:0006606 protein import into nucleus; GO:0090596 sensory organ morphogenesis; GO:0052548 regulation of endopeptidase activity; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0040014 regulation of multicellular organism growth; GO:0010950 positive regulation of endopeptidase activity; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0048592 eye morphogenesis; GO:0060148 positive regulation of posttranscriptional gene silencing; GO:0046530 photoreceptor cell differentiation; GO:0044763 single-organism cellular process; GO:0034249 negative regulation of cellular amide metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0002520 immune system development; GO:0051704 multi-organism process; GO:0006810 transport; GO:0010243 response to organonitrogen compound; GO:0042063 gliogenesis; GO:0006953 acute-phase response; GO:0031047 gene silencing by RNA; GO:0002526 acute inflammatory response; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:1901698 response to nitrogen compound; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0043367 CD4-positive, alpha-beta T cell differentiation; GO:0006913 nucleocytoplasmic transport; GO:0045981 positive regulation of nucleotide metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0010721 negative regulation of cell development; GO:0016071 mRNA metabolic process; GO:0060548 negative regulation of cell death; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0000003 reproduction; GO:0016310 phosphorylation; GO:0044707 single-multicellular organism process; GO:0045974 regulation of translation, ncRNA-mediated; GO:0007006 mitochondrial membrane organization; GO:0097009 energy homeostasis; GO:1901700 response to oxygen-containing compound; GO:0071354 cellular response to interleukin-6; GO:0010310 regulation of hydrogen peroxide metabolic process; GO:0048519 negative regulation of biological process; GO:0043373 CD4-positive, alpha-beta T cell lineage commitment; GO:0045892 negative regulation of transcription, DNA-templated; GO:0030098 lymphocyte differentiation; GO:0009653 anatomical structure morphogenesis; GO:0042493 response to drug; GO:0001654 eye development; GO:0009299 mRNA transcription; GO:0046483 heterocycle metabolic process; GO:0051345 positive regulation of hydrolase activity; GO:0006139 nucleobase-containing compound metabolic process; GO:2000145 regulation of cell motility; GO:0009889 regulation of biosynthetic process; GO:0042093 T-helper cell differentiation; GO:0044744 protein targeting to nucleus; GO:0033500 carbohydrate homeostasis; GO:1902580 single-organism cellular localization; GO:1902680 positive regulation of RNA biosynthetic process; GO:2000378 negative regulation of reactive oxygen species metabolic process; GO:0007631 feeding behavior; GO:0034613 cellular protein localization; GO:0030217 T cell differentiation; GO:0048878 chemical homeostasis; GO:1901215 negative regulation of neuron death; GO:1904683 regulation of metalloendopeptidase activity; GO:0006950 response to stress; GO:0051270 regulation of cellular component movement; GO:0042789 mRNA transcription fro"}},"GO:0016020 membrane; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044454 nuclear chromosome part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0019866 organelle inner membrane; GO:0000790 nuclear chromatin; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0031981 nuclear lumen; GO:0044798 nuclear transcription factor complex; GO:0005667 transcription factor complex; GO:0005829 cytosol; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0090575 RNA polymerase II transcription factor complex; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0000785 chromatin; GO:0031975 envelope; GO:0000228 nuclear chromosome; GO:0043234 protein complex; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding; GO:0031490 chromatin DNA binding; GO:0019903 protein phosphatase binding; GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding; GO:0035259 glucocorticoid receptor binding; GO:0005102 receptor binding; GO:0003690 double-stranded DNA binding; GO:0019901 protein kinase binding; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:0003682 chromatin binding; GO:0051427 hormone receptor binding; GO:0000987 core promoter proximal region sequence-specific DNA binding; GO:0004871 signal transducer activity; GO:0003700 transcription factor activity, sequence-specific DNA binding; GO:1901363 heterocyclic compound binding; GO:0000975 regulatory region DNA binding; GO:0097159 organic cyclic compound binding; GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding; GO:0042802 identical protein binding; GO:0070491 repressing transcription factor binding; GO:0001085 RNA polymerase II transcription factor binding; GO:0005488 binding; GO:0001071 nucleic acid binding transcription factor activity; GO:0035258 steroid hormone receptor binding; GO:0001664 G-protein coupled receptor binding; GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding; GO:0019902 phosphatase binding; GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding; GO:0003677 DNA binding; GO:0001103 RNA polymerase II repressing transcription factor binding; GO:0000976 transcription regulatory region sequence-specific DNA binding; GO:0005126 cytokine receptor binding; GO:0001012 RNA polymerase II regulatory region DNA binding; GO:1990837 sequence-specific double-stranded DNA binding; GO:0031730 CCR5 chemokine receptor binding; GO:0019900 kinase binding; GO:0043565 sequence-specific DNA binding; GO:0001159 core promoter proximal region DNA binding; GO:0098531 transcription factor activity, direct ligand regulated sequence-specific DNA binding; GO:0001067 regulatory region nucleic acid binding; GO:0048020 CCR chemokine receptor binding; GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding; GO:0042803 protein homodimerization activity; GO:0044212 transcription regulatory region DNA binding; GO:0042379 chemokine receptor binding; GO:0003676 nucleic acid binding; GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding; GO:0035257 nuclear hormone receptor binding; GO:0008134 transcription factor binding; GO:0019899 enzyme binding; ","K04692","STAT3; signal transducer and activator of transcription 3","hsa05221 Acute myeloid leukemia - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); hsa05160 Hepatitis C - Homo sapiens (human); hsa04217 Necroptosis - Homo sapiens (human); hsa05167 Kaposi's sarcoma-associated herpesvirus infection - Homo sapiens (human); hsa05162 Measles - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa05206 MicroRNAs in cancer - Homo sapiens (human); hsa04931 Insulin resistance - Homo sapiens (human); hsa05145 Toxoplasmosis - Homo sapiens (human); hsa04062 Chemokine signaling pathway - Homo sapiens (human); hsa05223 Non-small cell lung cancer - Homo sapiens (human); hsa04920 Adipocytokine signaling pathway - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa04066 HIF-1 signaling pathway - Homo sapiens (human); hsa04933 AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human); hsa04659 Th17 cell differentiation - Homo sapiens (human); hsa05321 Inflammatory bowel disease (IBD) - Homo sapiens (human); hsa05203 Viral carcinogenesis - Homo sapiens (human); hsa04068 FoxO signaling pathway - Homo sapiens (human); hsa04917 Prolactin signaling pathway - Homo sapiens (human); hsa05161 Hepatitis B - Homo sapiens (human); hsa01521 EGFR tyrosine kinase inhibitor resistance - Homo sapiens (human); hsa05212 Pancreatic cancer - Homo sapiens (human); hsa04630 Jak-STAT signaling pathway - Homo sapiens (human); hsa04550 Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human); ","IPR013801; IPR000980; IPR012345; IPR008967; IPR011992; IPR013799; IPR013800; IPR015988; ","\"STAT transcription factor, DNA-binding; SH2 domain; STAT transcription factor, DNA-binding, subdomain; p53-like transcription factor, DNA-binding; EF-hand domain pair; STAT transcription factor, protein interaction; STAT transcription factor, all-alpha domain; STAT transcription factor, coiled coil; \"\r"]
["P40939","Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA","HADHA",82.999,232.23,37.2,23,45,23,1.046,1.093,1.079,0.926,0.948,0.935,0.873,0.000763,"mitochondria\r","GO:0034440 lipid oxidation; GO:0046486 glycerolipid metabolic process; GO:1901700 response to oxygen-containing compound; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0042493 response to drug; GO:0046471 phosphatidylglycerol metabolic process; GO:0008152 metabolic process; GO:0030258 lipid modification; GO:0006650 glycerophospholipid metabolic process; GO:0009719 response to endogenous stimulus; GO:0044248 cellular catabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:1901652 response to peptide; GO:0009987 cellular process; GO:0006629 lipid metabolic process; GO:0016042 lipid catabolic process; GO:0019395 fatty acid oxidation; GO:0032048 cardiolipin metabolic process; GO:0055114 oxidation-reduction process; GO:0044712 single-organism catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006635 fatty acid beta-oxidation; GO:0072329 monocarboxylic acid catabolic process; GO:0044282 small molecule catabolic process; GO:0010033 response to organic substance; GO:0006631 fatty acid metabolic process; GO:0044238 primary metabolic process; GO:0046395 carboxylic acid catabolic process; GO:1901575 organic substance catabolic process; GO:0010243 response to organonitrogen compound; GO:0032868 response to insulin; GO:0042221 response to chemical; GO:0043434 response to peptide hormone; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0035965 cardiolipin acyl-chain remodeling; GO:1901698 response to nitrogen compound; GO:0019752 carboxylic acid metabolic process; GO:0016054 organic acid catabolic process; GO:0019637 organophosphate metabolic process; GO:0044242 cellular lipid catabolic process; GO:0006644 phospholipid metabolic process; GO:0009725 response to hormone; GO:0006082 organic acid metabolic process; GO:0009062 fatty acid catabolic process; GO:0009056 catabolic process; GO:0043436 oxoacid metabolic process; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0036125 fatty acid beta-oxidation multienzyme complex; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0043233 organelle lumen; GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0042645 mitochondrial nucleoid; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031012 extracellular matrix; GO:0016507 mitochondrial fatty acid beta-oxidation multienzyme complex; GO:0031975 envelope; GO:0031966 mitochondrial membrane; GO:0009295 nucleoid; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0005515 protein binding; GO:0016835 carbon-oxygen lyase activity; GO:0016614 oxidoreductase activity, acting on CH-OH group of donors; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; GO:0016746 transferase activity, transferring acyl groups; GO:0000062 fatty-acyl-CoA binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0003988 acetyl-CoA C-acyltransferase activity; GO:0043168 anion binding; GO:0003985 acetyl-CoA C-acetyltransferase activity; GO:0016740 transferase activity; GO:0016508 long-chain-enoyl-CoA hydratase activity; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0016829 lyase activity; GO:0016836 hydro-lyase activity; GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity; GO:0000166 nucleotide binding; GO:0048037 cofactor binding; GO:1901681 sulfur compound binding; GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups; GO:0016407 acetyltransferase activity; GO:0016491 oxidoreductase activity; GO:0004300 enoyl-CoA hydratase activity; GO:0051287 NAD binding; GO:0016408 C-acyltransferase activity; GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity; GO:0016453 C-acetyltransferase activity; GO:0032403 protein complex binding; GO:0050662 coenzyme binding; GO:0036094 small molecule binding; ","K07515","HADHA; enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.211]","hsa00280 Valine, leucine and isoleucine degradation - Homo sapiens (human); hsa00310 Lysine degradation - Homo sapiens (human); hsa00640 Propanoate metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa01212 Fatty acid metabolism - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); hsa00062 Fatty acid elongation - Homo sapiens (human); hsa01040 Biosynthesis of unsaturated fatty acids - Homo sapiens (human); hsa00071 Fatty acid degradation - Homo sapiens (human); hsa00650 Butanoate metabolism - Homo sapiens (human); hsa00410 beta-Alanine metabolism - Homo sapiens (human); hsa00380 Tryptophan metabolism - Homo sapiens (human); ","IPR008927; IPR029045; IPR013328; IPR016040; IPR006176; IPR006108; ","\"6-phosphogluconate dehydrogenase C-terminal domain-like; ClpP/crotonase-like domain; 6-phosphogluconate dehydrogenase, domain 2; NAD(P)-binding domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding; 3-hydroxyacyl-CoA dehydrogenase, C-terminal; \"\r"]
["P41208","Centrin-2 OS=Homo sapiens OX=9606 GN=CETN2","CETN2",19.738,4.4445,12.8,2,2,2,1.028,1.044,0.95,1.079,0.964,0.95,0.99,0.844,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0007098 centrosome cycle; GO:0022414 reproductive process; GO:0006289 nucleotide-excision repair; GO:0007067 mitotic nuclear division; GO:0032392 DNA geometric change; GO:0060271 cilium assembly; GO:0044699 single-organism process; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0044782 cilium organization; GO:0008152 metabolic process; GO:0007099 centriole replication; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0044702 single organism reproductive process; GO:0044770 cell cycle phase transition; GO:0043170 macromolecule metabolic process; GO:0051726 regulation of cell cycle; GO:0071824 protein-DNA complex subunit organization; GO:0071103 DNA conformation change; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0051298 centrosome duplication; GO:0019953 sexual reproduction; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0065004 protein-DNA complex assembly; GO:0000226 microtubule cytoskeleton organization; GO:1902589 single-organism organelle organization; GO:0000715 nucleotide-excision repair, DNA damage recognition; GO:0050789 regulation of biological process; GO:0051302 regulation of cell division; GO:0090304 nucleic acid metabolic process; GO:0030030 cell projection organization; GO:0044260 cellular macromolecule metabolic process; GO:0098534 centriole assembly; GO:0051301 cell division; GO:0000086 G2/M transition of mitotic cell cycle; GO:0048609 multicellular organismal reproductive process; GO:0000003 reproduction; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0033554 cellular response to stress; GO:0006725 cellular aromatic compound metabolic process; GO:0006259 DNA metabolic process; GO:0048285 organelle fission; GO:0051297 centrosome organization; GO:0097711 ciliary basal body docking; GO:0050896 response to stimulus; GO:1903047 mitotic cell cycle process; GO:0022406 membrane docking; GO:0032465 regulation of cytokinesis; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0070925 organelle assembly; GO:0070911 global genome nucleotide-excision repair; GO:0034641 cellular nitrogen compound metabolic process; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0044772 mitotic cell cycle phase transition; GO:0034622 cellular macromolecular complex assembly; GO:0048232 male gamete generation; GO:0006950 response to stress; GO:0000717 nucleotide-excision repair, DNA duplex unwinding; GO:0007283 spermatogenesis; GO:0032508 DNA duplex unwinding; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:0007017 microtubule-based process; GO:0007276 gamete generation; GO:0006974 cellular response to DNA damage stimulus; GO:0030031 cell projection assembly; GO:0043933 macromolecular complex subunit organization; GO:0032504 multicellular organism reproduction; GO:0006281 DNA repair; GO:0051276 chromosome organization; GO:0006996 organelle organization; GO:0031023 microtubule organizing center organization; GO:0044703 multi-organism reproductive process; GO:0006294 nucleotide-excision repair, preincision complex assembly; GO:0000280 nuclear division; GO:0044839 cell cycle G2/M phase transition; GO:0022402 cell cycle process; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0044450 microtubule organizing center part; GO:0035869 ciliary transition zone; GO:0005737 cytoplasm; GO:0097730 non-motile cilium; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0097731 9+0 non-motile cilium; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0031974 membrane-enclosed lumen; GO:0005815 microtubule organizing center; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0044441 ciliary part; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043233 organelle lumen; GO:0071942 XPC complex; GO:0043229 intracellular organelle; GO:0005929 cilium; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0036064 ciliary basal body; GO:1990391 DNA repair complex; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0032391 photoreceptor connecting cilium; GO:0005813 centrosome; GO:0005814 centriole; GO:0097733 photoreceptor cell cilium; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0000109 nucleotide-excision repair complex; GO:0044428 nuclear part; ","GO:0008092 cytoskeletal protein binding; GO:0008017 microtubule binding; GO:0005488 binding; GO:0043167 ion binding; GO:0032795 heterotrimeric G-protein binding; GO:0044877 macromolecular complex binding; GO:0031683 G-protein beta/gamma-subunit complex binding; GO:0015631 tubulin binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0005509 calcium ion binding; GO:0032403 protein complex binding; ","K10840","CETN2; centrin-2","hsa03420 Nucleotide excision repair - Homo sapiens (human); ","IPR002048; IPR011992; ","EF-hand domain; EF-hand domain pair; \r"]
["P41223","Protein BUD31 homolog OS=Homo sapiens OX=9606 GN=BUD31","BUD31",17,11.224,27.1,4,4,4,0.694,1.191,0.845,0.923,1.04,1.301,1.196,0.359,"extracellular\r","GO:2000273 positive regulation of receptor activity; GO:0023051 regulation of signaling; GO:0044237 cellular metabolic process; GO:0010469 regulation of receptor activity; GO:0033145 positive regulation of intracellular steroid hormone receptor signaling pathway; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0010646 regulation of cell communication; GO:0044093 positive regulation of molecular function; GO:0043170 macromolecule metabolic process; GO:0006396 RNA processing; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0060765 regulation of androgen receptor signaling pathway; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity; GO:2000825 positive regulation of androgen receptor activity; GO:0031323 regulation of cellular metabolic process; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0051090 regulation of sequence-specific DNA binding transcription factor activity; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0033143 regulation of intracellular steroid hormone receptor signaling pathway; GO:0016071 mRNA metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:2000823 regulation of androgen receptor activity; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0023056 positive regulation of signaling; GO:0000375 RNA splicing, via transesterification reactions; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0010647 positive regulation of cell communication; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0009966 regulation of signal transduction; GO:0006355 regulation of transcription, DNA-templated; GO:0006807 nitrogen compound metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0010467 gene expression; GO:0009967 positive regulation of signal transduction; GO:0048584 positive regulation of response to stimulus; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005681 spliceosomal complex; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity; GO:0005102 receptor binding; GO:0005488 binding; GO:0001071 nucleic acid binding transcription factor activity; GO:0035257 nuclear hormone receptor binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0005515 protein binding; GO:0003713 transcription coactivator activity; GO:0051427 hormone receptor binding; GO:0003712 transcription cofactor activity; GO:0000988 transcription factor activity, protein binding; GO:0003700 transcription factor activity, sequence-specific DNA binding; ","K12873","BUD31; bud site selection protein 31","hsa03040 Spliceosome - Homo sapiens (human); "]
["P41226","Ubiquitin-like modifier-activating enzyme 7 OS=Homo sapiens OX=9606 GN=UBA7","UBA7",111.69,33.428,5.8,5,5,5,0.907,0.816,1.151,1.15,0.952,1.023,1.087,0.474,"cyto_nucl\r","GO:0033554 cellular response to stress; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0032479 regulation of type I interferon production; GO:0044257 cellular protein catabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0006259 DNA metabolic process; GO:0044267 cellular protein metabolic process; GO:0051241 negative regulation of multicellular organismal process; GO:0000731 DNA synthesis involved in DNA repair; GO:0009058 biosynthetic process; GO:0048519 negative regulation of biological process; GO:0001818 negative regulation of cytokine production; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0051239 regulation of multicellular organismal process; GO:0006301 postreplication repair; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0019985 translesion synthesis; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0071897 DNA biosynthetic process; GO:0006508 proteolysis; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0043632 modification-dependent macromolecule catabolic process; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0044265 cellular macromolecule catabolic process; GO:0006950 response to stress; GO:0016567 protein ubiquitination; GO:0019941 modification-dependent protein catabolic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0006974 cellular response to DNA damage stimulus; GO:1901575 organic substance catabolic process; GO:0006281 DNA repair; GO:0050789 regulation of biological process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0090304 nucleic acid metabolic process; GO:0032446 protein modification by small protein conjugation; GO:0030163 protein catabolic process; GO:0009057 macromolecule catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0001817 regulation of cytokine production; GO:0032020 ISG15-protein conjugation; GO:0006464 cellular protein modification process; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:0032480 negative regulation of type I interferon production; GO:0009056 catabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0008641 small protein activating enzyme activity; GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0019787 ubiquitin-like protein transferase activity; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016874 ligase activity; GO:0005515 protein binding; GO:0016877 ligase activity, forming carbon-sulfur bonds; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0019782 ISG15 activating enzyme activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0004842 ubiquitin-protein transferase activity; GO:0032550 purine ribonucleoside binding; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K10698","UBE1L; ubiquitin-activating enzyme E1-like [EC:6.2.1.45]","hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); ","IPR032418; IPR019572; IPR000594; IPR016040; IPR032420; IPR018965; ","\"Ubiquitin-activating enzyme E1, FCCH domain; Ubiquitin-activating enzyme, catalytic cysteine domain; THIF-type NAD/FAD binding fold; NAD(P)-binding domain; Ubiquitin-activating enzyme E1, four-helix bundle; Ubiquitin-activating enzyme E1, C-terminal; \"\r"]
["P41252","Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS","IARS",144.5,41.236,11.8,13,15,13,0.929,0.919,0.916,1.052,1.088,1.111,1.176,0.000598,"cytoplasm\r","GO:0001649 osteoblast differentiation; GO:0065008 regulation of biological quality; GO:0006518 peptide metabolic process; GO:0010608 posttranscriptional regulation of gene expression; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0006428 isoleucyl-tRNA aminoacylation; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0006418 tRNA aminoacylation for protein translation; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006412 translation; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0043043 peptide biosynthetic process; GO:0001503 ossification; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0016070 RNA metabolic process; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0090304 nucleic acid metabolic process; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006082 organic acid metabolic process; GO:0043436 oxoacid metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0044267 cellular protein metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0043039 tRNA aminoacylation; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006448 regulation of translational elongation; GO:0006450 regulation of translational fidelity; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0034248 regulation of cellular amide metabolic process; GO:0006399 tRNA metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0051246 regulation of protein metabolic process; GO:0006417 regulation of translation; GO:0044767 single-organism developmental process; GO:0043038 amino acid activation; GO:0019752 carboxylic acid metabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0034660 ncRNA metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds; GO:0052689 carboxylic ester hydrolase activity; GO:1901265 nucleoside phosphate binding; GO:0016875 ligase activity, forming carbon-oxygen bonds; GO:0016874 ligase activity; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0000049 tRNA binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0051020 GTPase binding; GO:0004812 aminoacyl-tRNA ligase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003723 RNA binding; GO:0005524 ATP binding; GO:0002161 aminoacyl-tRNA editing activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0004822 isoleucine-tRNA ligase activity; GO:0000166 nucleotide binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003676 nucleic acid binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019899 enzyme binding; GO:0036094 small molecule binding; ","K01870","IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]","hsa00970 Aminoacyl-tRNA biosynthesis - Homo sapiens (human); ","IPR014729; IPR009008; IPR013155; IPR033709; IPR002300; IPR009080; ","\"Rossmann-like alpha/beta/alpha sandwich fold; Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain; Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding; Isoleucyl tRNA synthetase type 2, anticodon-binding domain; Aminoacyl-tRNA synthetase, class Ia; Aminoacyl-tRNA synthetase, class Ia, anticodon-binding; \"\r"]
["P41567","Eukaryotic translation initiation factor 1 OS=Homo sapiens OX=9606 GN=EIF1","EIF1",12.732,24.702,27.4,3,4,3,0.889,0.834,0.882,1.215,1.045,1.13,1.301,0.00546,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0006518 peptide metabolic process; GO:0010608 posttranscriptional regulation of gene expression; GO:0060255 regulation of macromolecule metabolic process; GO:0044267 cellular protein metabolic process; GO:0009058 biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0007549 dosage compensation; GO:0009889 regulation of biosynthetic process; GO:0006413 translational initiation; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006412 translation; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0006950 response to stress; GO:0080090 regulation of primary metabolic process; GO:0043043 peptide biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0043603 cellular amide metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0034248 regulation of cellular amide metabolic process; GO:0040029 regulation of gene expression, epigenetic; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0009048 dosage compensation by inactivation of X chromosome; GO:0051246 regulation of protein metabolic process; GO:0006417 regulation of translation; GO:0044260 cellular macromolecule metabolic process; GO:0006446 regulation of translational initiation; GO:0019222 regulation of metabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0008135 translation factor activity, RNA binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0003743 translation initiation factor activity; ","K03113","EIF1; translation initiation factor 1","hsa03013 RNA transport - Homo sapiens (human); ","IPR001950; ","SUI1 domain; \r"]
["P42126","Enoyl-CoA delta isomerase 1, mitochondrial OS=Homo sapiens OX=9606 GN=ECI1","ECI1",32.816,56.601,23.2,5,9,5,1.144,1.116,1.194,0.89,0.86,0.837,0.749,0.000402,"mitochondria\r","GO:0034440 lipid oxidation; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0030258 lipid modification; GO:0044248 cellular catabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0009987 cellular process; GO:0006629 lipid metabolic process; GO:0016042 lipid catabolic process; GO:0019395 fatty acid oxidation; GO:0055114 oxidation-reduction process; GO:0044712 single-organism catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006635 fatty acid beta-oxidation; GO:0072329 monocarboxylic acid catabolic process; GO:0044282 small molecule catabolic process; GO:0006631 fatty acid metabolic process; GO:0044238 primary metabolic process; GO:0046395 carboxylic acid catabolic process; GO:1901575 organic substance catabolic process; GO:0044710 single-organism metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0016054 organic acid catabolic process; GO:0044242 cellular lipid catabolic process; GO:0006082 organic acid metabolic process; GO:0009062 fatty acid catabolic process; GO:0009056 catabolic process; GO:0043436 oxoacid metabolic process; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0019866 organelle inner membrane; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005759 mitochondrial matrix; GO:0044429 mitochondrial part; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031975 envelope; GO:0043230 extracellular organelle; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0016853 isomerase activity; GO:0003824 catalytic activity; GO:0016829 lyase activity; GO:0016836 hydro-lyase activity; GO:0016860 intramolecular oxidoreductase activity; GO:0004165 dodecenoyl-CoA delta-isomerase activity; GO:0016835 carbon-oxygen lyase activity; GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds; GO:0004300 enoyl-CoA hydratase activity; ","K13238","ECI1; Delta3-Delta2-enoyl-CoA isomerase [EC:5.3.3.8]","hsa00071 Fatty acid degradation - Homo sapiens (human); ","IPR029045; ","ClpP/crotonase-like domain; \r"]
["P42229","Signal transducer and activator of transcription 5A OS=Homo sapiens OX=9606 GN=STAT5A","STAT5A",90.646,32.313,12.6,10,14,10,1.067,1.057,1.022,1.012,0.897,0.962,0.913,0.0684,"cytoplasm\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0030335 positive regulation of cell migration; GO:0048732 gland development; GO:0007166 cell surface receptor signaling pathway; GO:0097659 nucleic acid-templated transcription; GO:0018212 peptidyl-tyrosine modification; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0071345 cellular response to cytokine stimulus; GO:0010594 regulation of endothelial cell migration; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0050678 regulation of epithelial cell proliferation; GO:0032879 regulation of localization; GO:0032787 monocarboxylic acid metabolic process; GO:0009719 response to endogenous stimulus; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:1901652 response to peptide; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0006790 sulfur compound metabolic process; GO:0072350 tricarboxylic acid metabolic process; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0006105 succinate metabolic process; GO:0040014 regulation of multicellular organism growth; GO:0097696 STAT cascade; GO:0010632 regulation of epithelial cell migration; GO:0080090 regulation of primary metabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0006107 oxaloacetate metabolic process; GO:0032774 RNA biosynthetic process; GO:0051272 positive regulation of cellular component movement; GO:0031323 regulation of cellular metabolic process; GO:0001938 positive regulation of endothelial cell proliferation; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:1903506 regulation of nucleic acid-templated transcription; GO:0010243 response to organonitrogen compound; GO:0048513 animal organ development; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:1901698 response to nitrogen compound; GO:0006464 cellular protein modification process; GO:1901362 organic cyclic compound biosynthetic process; GO:0043436 oxoacid metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016310 phosphorylation; GO:0044707 single-multicellular organism process; GO:0007259 JAK-STAT cascade; GO:0042127 regulation of cell proliferation; GO:0044267 cellular protein metabolic process; GO:1901700 response to oxygen-containing compound; GO:2000147 positive regulation of cell motility; GO:0051239 regulation of multicellular organismal process; GO:0030879 mammary gland development; GO:0006573 valine metabolic process; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:2000145 regulation of cell motility; GO:0051171 regulation of nitrogen compound metabolic process; GO:0001936 regulation of endothelial cell proliferation; GO:0007275 multicellular organism development; GO:0046449 creatinine metabolic process; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0030334 regulation of cell migration; GO:0006600 creatine metabolic process; GO:0010033 response to organic substance; GO:1901605 alpha-amino acid metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0043535 regulation of blood vessel endothelial cell migration; GO:0006549 isoleucine metabolic process; GO:0006793 phosphorus metabolic process; GO:0043412 macromolecule modification; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0008284 positive regulation of cell proliferation; GO:1901564 organonitrogen compound metabolic process; GO:0038161 prolactin signaling pathway; GO:0040017 positive regulation of locomotion; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0000255 allantoin metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0006520 cellular amino acid metabolic process; GO:0007154 cell communication; GO:1901653 cellular response to peptide; GO:0019694 alkanesulfonate metabolic process; GO:0006103 2-oxoglutarate metabolic process; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0070887 cellular response to chemical stimulus; GO:0043536 positive regulation of blood vessel endothelial cell migration; GO:0006629 lipid metabolic process; GO:0032502 developmental process; GO:0007595 lactation; GO:0072338 cellular lactam metabolic process; GO:0010468 regulation of gene expression; GO:0034097 response to cytokine; GO:0031326 regulation of cellular biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0043603 cellular amide metabolic process; GO:0023052 signaling; GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway; GO:0018108 peptidyl-tyrosine phosphorylation; GO:0016070 RNA metabolic process; GO:0006101 citrate metabolic process; GO:0071417 cellular response to organonitrogen compound; GO:0019530 taurine metabolic process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0043434 response to peptide hormone; GO:0006351 transcription, DNA-templated; GO:1901699 cellular response to nitrogen compound; GO:0032870 cellular response to hormone stimulus; GO:0019222 regulation of metabolic process; GO:0071378 cellular response to growth hormone stimulus; GO:0036211 protein modification process; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:0043648 dicarboxylic acid metabolic process; GO:0040008 regulation of growth; GO:0006725 cellular aromatic compound metabolic process; GO:0010595 positive regulation of endothelial cell migration; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0060396 growth hormone receptor signaling pathway; GO:0050896 response to stimulus; GO:0048638 regulation of developmental growth; GO:0071704 organic substance metabolic process; GO:0006468 protein phosphorylation; GO:0006575 cellular modified amino acid metabolic process; GO:0071375 cellular response to peptide hormone stimulus; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009081 branched-chain amino acid metabolic process; GO:0009987 cellular process; GO:0019221 cytokine-mediated signaling pathway; GO:0007589 body fluid secretion; GO:0050878 regulation of body fluid levels; GO:0006355 regulation of transcription, DNA-templated; GO:0035556 intracellular signal transduction; GO:0006807 nitrogen compound metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010634 positive regulation of epithelial cell migration; GO:0010556 regulation of macromolecule biosynthetic process; GO:0006631 fatty acid metabolic process; GO:0060416 response to growth hormone; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0009755 hormone-mediated signaling pathway; GO:0018193 peptidyl-amino acid modification; GO:1901701 cellular response to oxygen-containing compound; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0071495 cellular response to endogenous stimulus; GO:0044767 single-organism developmental process; GO:0019752 carboxylic acid metabolic process; GO:0010467 gene expression; GO:0009725 response to hormone; GO:0040012 regulation of locomotion; GO:0065007 biological regulation; GO:0050679 positive regulation of epithelial cell proliferation; ","GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0003677 DNA binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0004713 protein tyrosine kinase activity; GO:0005515 protein binding; GO:0004672 protein kinase activity; GO:0004871 signal transducer activity; GO:0003700 transcription factor activity, sequence-specific DNA binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016301 kinase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0001071 nucleic acid binding transcription factor activity; GO:0003676 nucleic acid binding; GO:0016740 transferase activity; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K11223","STAT5A; signal transducer and activator of transcription 5A","hsa05223 Non-small cell lung cancer - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa05221 Acute myeloid leukemia - Homo sapiens (human); hsa05220 Chronic myeloid leukemia - Homo sapiens (human); hsa04933 AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human); hsa04659 Th17 cell differentiation - Homo sapiens (human); hsa04217 Necroptosis - Homo sapiens (human); hsa05203 Viral carcinogenesis - Homo sapiens (human); hsa05162 Measles - Homo sapiens (human); hsa05166 HTLV-I infection - Homo sapiens (human); hsa04917 Prolactin signaling pathway - Homo sapiens (human); hsa04012 ErbB signaling pathway - Homo sapiens (human); hsa05161 Hepatitis B - Homo sapiens (human); hsa04658 Th1 and Th2 cell differentiation - Homo sapiens (human); hsa04630 Jak-STAT signaling pathway - Homo sapiens (human); ","IPR013801; IPR000980; IPR012345; IPR008967; IPR011992; IPR013800; IPR013799; IPR015988; ","\"STAT transcription factor, DNA-binding; SH2 domain; STAT transcription factor, DNA-binding, subdomain; p53-like transcription factor, DNA-binding; EF-hand domain pair; STAT transcription factor, all-alpha domain; STAT transcription factor, protein interaction; STAT transcription factor, coiled coil; \"\r"]
["P42345","Serine/threonine-protein kinase mTOR OS=Homo sapiens OX=9606 GN=MTOR","MTOR",288.89,27.161,2.3,5,6,5,1.082,0.974,1.024,0.944,0.998,1.011,0.959,0.323,"plasma membrane\r",{"$cut":{"chars":28668,"head":"GO:0044700 single organism signaling; GO:0002694 regulation of leukocyte activation; GO:0014013 regulation of gliogenesis; GO:0022414 reproductive process; GO:0010608 posttranscriptional regulation of gene expression; GO:0014742 positive regulation of muscle hypertrophy; GO:0032104 regulation of response to extracellular stimulus; GO:0003179 heart valve morphogenesis; GO:0044237 cellular metabolic process; GO:0001558 regulation of cell growth; GO:0006091 generation of precursor metabolites and energy; GO:0014072 response to isoquinoline alkaloid; GO:0010830 regulation of myotube differentiation; GO:0072527 pyrimidine-containing compound metabolic process; GO:0044057 regulation of system process; GO:0051493 regulation of cytoskeleton organization; GO:0051147 regulation of muscle cell differentiation; GO:0055013 cardiac muscle cell development; GO:0045945 positive regulation of transcription from RNA polymerase III promoter; GO:0080090 regulation of primary metabolic process; GO:0060537 muscle tissue development; GO:0050879 multicellular organismal movement; GO:1904056 positive regulation of cholangiocyte proliferation; GO:0010506 regulation of autophagy; GO:1903959 regulation of anion transmembrane transport; GO:0016241 regulation of macroautophagy; GO:1901575 organic substance catabolic process; GO:0046890 regulation of lipid biosynthetic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0009112 nucleobase metabolic process; GO:0051149 positive regulation of muscle cell differentiation; GO:0032233 positive regulation of actin filament bundle assembly; GO:0045670 regulation of osteoclast differentiation; GO:0060548 negative regulation of cell death; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0072359 circulatory system development; GO:0043255 regulation of carbohydrate biosynthetic process; GO:0044707 single-multicellular organism process; GO:0016310 phosphorylation; GO:0042990 regulation of transcription factor import into nucleus; GO:0043487 regulation of RNA stability; GO:1903706 regulation of hemopoiesis; GO:0009653 anatomical structure morphogenesis; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:0044248 cellular catabolic process; GO:0061061 muscle structure development; GO:1902680 positive regulation of RNA biosynthetic process; GO:0051930 regulation of sensory perception of pain; GO:0001936 regulation of endothelial cell proliferation; GO:0048015 phosphatidylinositol-mediated signaling; GO:0043276 anoikis; GO:0044711 single-organism biosynthetic process; GO:0009416 response to light stimulus; GO:0060284 regulation of cell development; GO:0002376 immune system process; GO:0032101 regulation of response to external stimulus; GO:0010033 response to organic substance; GO:0014735 regulation of muscle atrophy; GO:0034766 negative regulation of ion transmembrane transport; GO:0051492 regulation of stress fiber assembly; GO:1903321 negative regulation of protein modification by small protein conjugation or removal; GO:0019217 regulation of fatty acid metabolic process; GO:0070873 regulation of glycogen metabolic process; GO:0043412 macromolecule modification; GO:0008284 positive regulation of cell proliferation; GO:1904213 negative regulation of iodide transmembrane transport; GO:0003012 muscle system process; GO:0018209 peptidyl-serine modification; GO:0048869 cellular developmental process; GO:1901836 regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter; GO:0006796 phosphate-containing compound metabolic process; GO:0009611 response to wounding; GO:0048017 inositol lipid-mediated signaling; GO:0007165 signal transduction; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0046777 protein autophosphorylation; GO:0031644 regulation of neurological system process; GO:0051726 regulation of cell cycle; GO:0045937 positive regulation of phosphate "}},"GO:0016020 membrane; GO:0030425 dendrite; GO:0019867 outer membrane; GO:0019898 extrinsic component of membrane; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0043025 neuronal cell body; GO:0032991 macromolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0005765 lysosomal membrane; GO:0016605 PML body; GO:0005654 nucleoplasm; GO:0005622 intracellular; GO:0005764 lysosome; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0005789 endoplasmic reticulum membrane; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0042995 cell projection; GO:0031967 organelle envelope; GO:0031981 nuclear lumen; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0031975 envelope; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005942 phosphatidylinositol 3-kinase complex; GO:0043234 protein complex; GO:0031966 mitochondrial membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0061695 transferase complex, transferring phosphorus-containing groups; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0038201 TOR complex; GO:0031974 membrane-enclosed lumen; GO:0005740 mitochondrial envelope; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0044431 Golgi apparatus part; GO:0031968 organelle outer membrane; GO:0031931 TORC1 complex; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0044429 mitochondrial part; GO:0005741 mitochondrial outer membrane; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0031932 TORC2 complex; GO:1990234 transferase complex; GO:0005829 cytosol; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0005634 nucleus; GO:0044432 endoplasmic reticulum part; GO:0005774 vacuolar membrane; GO:0044297 cell body; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0000182 rDNA binding; GO:1901265 nucleoside phosphate binding; GO:0080084 5S rDNA binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0003690 double-stranded DNA binding; GO:0019901 protein kinase binding; GO:0001016 RNA polymerase III regulatory region DNA binding; GO:0005515 protein binding; GO:0004672 protein kinase activity; GO:0001032 RNA polymerase III type 3 promoter DNA binding; GO:0001031 RNA polymerase III type 2 promoter DNA binding; GO:1901363 heterocyclic compound binding; GO:0000975 regulatory region DNA binding; GO:0097159 organic cyclic compound binding; GO:0016301 kinase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003677 DNA binding; GO:0005524 ATP binding; GO:1990837 sequence-specific double-stranded DNA binding; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0043565 sequence-specific DNA binding; GO:0019900 kinase binding; GO:0001030 RNA polymerase III type 1 promoter DNA binding; GO:0051219 phosphoprotein binding; GO:0043022 ribosome binding; GO:0032549 ribonucleoside binding; GO:0001067 regulatory region nucleic acid binding; GO:0097367 carbohydrate derivative binding; GO:0044212 transcription regulatory region DNA binding; GO:0003676 nucleic acid binding; GO:0019904 protein domain specific binding; GO:0004674 protein serine/threonine kinase activity; GO:0032555 purine ribonucleotide binding; GO:0001156 TFIIIC-class transcription factor binding; GO:0001025 RNA polymerase III transcription factor binding; GO:0001883 purine nucleoside binding; GO:0008134 transcription factor binding; GO:0043021 ribonucleoprotein complex binding; GO:0019899 enzyme binding; GO:0036094 small molecule binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K07203","MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]","hsa04072 Phospholipase D signaling pathway - Homo sapiens (human); hsa05221 Acute myeloid leukemia - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa04150 mTOR signaling pathway - Homo sapiens (human); hsa05230 Central carbon metabolism in cancer - Homo sapiens (human); hsa04152 AMPK signaling pathway - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa05206 MicroRNAs in cancer - Homo sapiens (human); hsa04931 Insulin resistance - Homo sapiens (human); hsa04140 Autophagy - animal - Homo sapiens (human); hsa04920 Adipocytokine signaling pathway - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa04659 Th17 cell differentiation - Homo sapiens (human); hsa04211 Longevity regulating pathway - Homo sapiens (human); hsa05224 Breast cancer - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa01522 Endocrine resistance - Homo sapiens (human); hsa04930 Type II diabetes mellitus - Homo sapiens (human); hsa05215 Prostate cancer - Homo sapiens (human); hsa01521 EGFR tyrosine kinase inhibitor resistance - Homo sapiens (human); hsa05210 Colorectal cancer - Homo sapiens (human); hsa04630 Jak-STAT signaling pathway - Homo sapiens (human); hsa05231 Choline metabolism in cancer - Homo sapiens (human); hsa04218 Cellular senescence - Homo sapiens (human); hsa04371 Apelin signaling pathway - Homo sapiens (human); hsa04910 Insulin signaling pathway - Homo sapiens (human); hsa05167 Kaposi's sarcoma-associated herpesvirus infection - Homo sapiens (human); hsa05225 Hepatocellular carcinoma - Homo sapiens (human); hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa04213 Longevity regulating pathway - multiple species - Homo sapiens (human); hsa04066 HIF-1 signaling pathway - Homo sapiens (human); hsa05214 Glioma - Homo sapiens (human); hsa05226 Gastric cancer - Homo sapiens (human); hsa04012 ErbB signaling pathway - Homo sapiens (human); hsa05212 Pancreatic cancer - Homo sapiens (human); hsa04136 Autophagy - other - Homo sapiens (human); ","IPR000403; IPR011990; IPR011989; IPR009076; IPR024585; IPR011009; IPR003151; IPR014009; IPR016024; IPR003152; ","\"Phosphatidylinositol 3-/4-kinase, catalytic domain; Tetratricopeptide-like helical domain; Armadillo-like helical; FKBP12-rapamycin binding domain; Domain of unknown function DUF3385,  target of rapamycin protein; Protein kinase-like domain; PIK-related kinase, FAT; PIK-related kinase; Armadillo-type fold; FATC domain; \"\r"]
["P42357","Histidine ammonia-lyase OS=Homo sapiens OX=9606 GN=HAL","HAL",72.697,8.6415,4.4,3,3,3,0.694,0.719,0.681,1.264,1.293,1.318,1.851,3.31e-06,"cytoplasm\r","GO:0043648 dicarboxylic acid metabolic process; GO:1901606 alpha-amino acid catabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0052803 imidazole-containing compound metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0019556 histidine catabolic process to glutamate and formamide; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0046483 heterocycle metabolic process; GO:0006547 histidine metabolic process; GO:0006536 glutamate metabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0044248 cellular catabolic process; GO:1901361 organic cyclic compound catabolic process; GO:0019557 histidine catabolic process to glutamate and formate; GO:0034641 cellular nitrogen compound metabolic process; GO:0009987 cellular process; GO:0009064 glutamine family amino acid metabolic process; GO:0052805 imidazole-containing compound catabolic process; GO:0044712 single-organism catabolic process; GO:0006548 histidine catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0044282 small molecule catabolic process; GO:0043603 cellular amide metabolic process; GO:0043606 formamide metabolic process; GO:0044238 primary metabolic process; GO:1901605 alpha-amino acid metabolic process; GO:0015942 formate metabolic process; GO:0046395 carboxylic acid catabolic process; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:1901565 organonitrogen compound catabolic process; GO:0044710 single-organism metabolic process; GO:0016054 organic acid catabolic process; GO:0019752 carboxylic acid metabolic process; GO:0009063 cellular amino acid catabolic process; GO:0006082 organic acid metabolic process; GO:0009056 catabolic process; GO:0043436 oxoacid metabolic process; GO:0046700 heterocycle catabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0044444 cytoplasmic part; ","GO:0016829 lyase activity; GO:0016840 carbon-nitrogen lyase activity; GO:0004397 histidine ammonia-lyase activity; GO:0016841 ammonia-lyase activity; GO:0003824 catalytic activity; ","K01745","hutH; histidine ammonia-lyase [EC:4.3.1.3]","hsa00340 Histidine metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR024083; IPR008948; ","\"Fumarase/histidase, N-terminal; L-Aspartase-like; \"\r"]
["P42704","Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC","LRPPRC",157.9,126.41,21.8,30,44,30,0.933,0.892,0.931,1.1,1.073,1.072,1.177,0.000639,"mitochondria\r","GO:0050658 RNA transport; GO:0097659 nucleic acid-templated transcription; GO:0010608 posttranscriptional regulation of gene expression; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0000961 negative regulation of mitochondrial RNA catabolic process; GO:0044237 cellular metabolic process; GO:0009451 RNA modification; GO:0051253 negative regulation of RNA metabolic process; GO:0000960 regulation of mitochondrial RNA catabolic process; GO:0051234 establishment of localization; GO:2001141 regulation of RNA biosynthetic process; GO:0010970 transport along microtubule; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0047497 mitochondrion transport along microtubule; GO:0050657 nucleic acid transport; GO:0015931 nucleobase-containing compound transport; GO:0043170 macromolecule metabolic process; GO:0033036 macromolecule localization; GO:0044765 single-organism transport; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:1902582 single-organism intracellular transport; GO:0016070 RNA metabolic process; GO:0006810 transport; GO:1903506 regulation of nucleic acid-templated transcription; GO:0034643 establishment of mitochondrion localization, microtubule-mediated; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0090305 nucleic acid phosphodiester bond hydrolysis; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0072384 organelle transport along microtubule; GO:0051640 organelle localization; GO:0046907 intracellular transport; GO:1902369 negative regulation of RNA catabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0051028 mRNA transport; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0030705 cytoskeleton-dependent intracellular transport; GO:0051236 establishment of RNA localization; GO:0099111 microtubule-based transport; GO:0071704 organic substance metabolic process; GO:0051646 mitochondrion localization; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0051654 establishment of mitochondrion localization; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0070129 regulation of mitochondrial translation; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902580 single-organism cellular localization; GO:0009895 negative regulation of catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006355 regulation of transcription, DNA-templated; GO:0006403 RNA localization; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0071702 organic substance transport; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0044238 primary metabolic process; GO:0051656 establishment of organelle localization; GO:1901576 organic substance biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0009892 negative regulation of metabolic process; GO:0007017 microtubule-based process; GO:0044249 cellular biosynthetic process; GO:0034248 regulation of cellular amide metabolic process; GO:0051641 cellular localization; GO:0007018 microtubule-based movement; GO:0031330 negative regulation of cellular catabolic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0051246 regulation of protein metabolic process; GO:0006417 regulation of translation; GO:0006928 movement of cell or subcellular component; GO:0010467 gene expression; GO:0051179 localization; GO:0043412 macromolecule modification; GO:0071705 nitrogen compound transport; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0019867 outer membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005874 microtubule; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0099512 supramolecular fiber; GO:0005623 cell; GO:0099080 supramolecular complex; GO:0044422 organelle part; GO:0005640 nuclear outer membrane; GO:0043228 non-membrane-bounded organelle; GO:0000793 condensed chromosome; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0005654 nucleoplasm; GO:0031965 nuclear membrane; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0098805 whole membrane; GO:0019866 organelle inner membrane; GO:0048471 perinuclear region of cytoplasm; GO:0031968 organelle outer membrane; GO:0043227 membrane-bounded organelle; GO:0005637 nuclear inner membrane; GO:0043233 organelle lumen; GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0042645 mitochondrial nucleoid; GO:0044429 mitochondrial part; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005635 nuclear envelope; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0005739 mitochondrion; GO:0099081 supramolecular polymer; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0031975 envelope; GO:0000228 nuclear chromosome; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0000794 condensed nuclear chromosome; GO:0009295 nucleoid; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0003723 RNA binding; GO:0003677 DNA binding; GO:0031625 ubiquitin protein ligase binding; GO:0015631 tubulin binding; GO:0003697 single-stranded DNA binding; GO:0016787 hydrolase activity; GO:0048487 beta-tubulin binding; GO:0005515 protein binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0008092 cytoskeletal protein binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0008017 microtubule binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0004518 nuclease activity; GO:0003676 nucleic acid binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0004519 endonuclease activity; GO:0019899 enzyme binding; ","K17964",null,null,"IPR011990; IPR033443; ","Tetratricopeptide-like helical domain; Pentacotripeptide-repeat region of PROPR; \r"]
["P42785","Lysosomal Pro-X carboxypeptidase OS=Homo sapiens OX=9606 GN=PRCP","PRCP",55.799,28.037,13.3,5,8,5,1.027,1.068,1.027,0.885,0.985,0.996,0.918,0.0951,"endoplasmic reticulum\r","GO:0065008 regulation of biological quality; GO:0007596 blood coagulation; GO:0045321 leukocyte activation; GO:0060055 angiogenesis involved in wound healing; GO:0001568 blood vessel development; GO:0023051 regulation of signaling; GO:0042593 glucose homeostasis; GO:0044699 single-organism process; GO:0010594 regulation of endothelial cell migration; GO:0048871 multicellular organismal homeostasis; GO:0051234 establishment of localization; GO:0009611 response to wounding; GO:0003085 negative regulation of systemic arterial blood pressure; GO:0008152 metabolic process; GO:0001525 angiogenesis; GO:0010646 regulation of cell communication; GO:0032879 regulation of localization; GO:0003073 regulation of systemic arterial blood pressure; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0048514 blood vessel morphogenesis; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0032502 developmental process; GO:0002443 leukocyte mediated immunity; GO:0010632 regulation of epithelial cell migration; GO:0007597 blood coagulation, intrinsic pathway; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0001944 vasculature development; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0002444 myeloid leukocyte mediated immunity; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0002526 acute inflammatory response; GO:0032940 secretion by cell; GO:0006954 inflammatory response; GO:0048583 regulation of response to stimulus; GO:0019222 regulation of metabolic process; GO:0006952 defense response; GO:0043299 leukocyte degranulation; GO:0050817 coagulation; GO:0003013 circulatory system process; GO:2000377 regulation of reactive oxygen species metabolic process; GO:0048856 anatomical structure development; GO:0002155 regulation of thyroid hormone mediated signaling pathway; GO:0002353 plasma kallikrein-kinin cascade; GO:0050794 regulation of cellular process; GO:0008217 regulation of blood pressure; GO:0072359 circulatory system development; GO:0044707 single-multicellular organism process; GO:0002254 kinin cascade; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0097009 energy homeostasis; GO:0045776 negative regulation of blood pressure; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:0007599 hemostasis; GO:0071704 organic substance metabolic process; GO:0009653 anatomical structure morphogenesis; GO:0042592 homeostatic process; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:2000145 regulation of cell motility; GO:0008015 blood circulation; GO:0033500 carbohydrate homeostasis; GO:0006508 proteolysis; GO:0007275 multicellular organism development; GO:0036230 granulocyte activation; GO:0009966 regulation of signal transduction; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0003008 system process; GO:0050878 regulation of body fluid levels; GO:0006950 response to stress; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0030334 regulation of cell migration; GO:0072376 protein activation cascade; GO:0072358 cardiovascular system development; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:0043312 neutrophil degranulation; GO:0072378 blood coagulation, fibrin clot formation; GO:0002263 cell activation involved in immune response; GO:0002366 leukocyte activation involved in immune response; GO:0043535 regulation of blood vessel endothelial cell migration; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0042060 wound healing; GO:0044767 single-organism developmental process; GO:0001775 cell activation; GO:0040012 regulation of locomotion; GO:0051179 localization; GO:0006955 immune response; GO:0006887 exocytosis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0005765 lysosomal membrane; GO:0044464 cell part; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0070820 tertiary granule; GO:0044446 intracellular organelle part; GO:0035577 azurophil granule membrane; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0042582 azurophil granule; GO:0098852 lytic vacuole membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0030667 secretory granule membrane; GO:0101003 ficolin-1-rich granule membrane; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0045178 basal part of cell; ","GO:0004180 carboxypeptidase activity; GO:0008233 peptidase activity; GO:0008238 exopeptidase activity; GO:0017171 serine hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0008236 serine-type peptidase activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0004185 serine-type carboxypeptidase activity; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0070008 serine-type exopeptidase activity; ","K01285","PRCP; lysosomal Pro-X carboxypeptidase [EC:3.4.16.2]","hsa04974 Protein digestion and absorption - Homo sapiens (human); hsa04614 Renin-angiotensin system - Homo sapiens (human); ","IPR029058; ","Alpha/Beta hydrolase fold; \r"]
["P43003","Excitatory amino acid transporter 1 OS=Homo sapiens OX=9606 GN=SLC1A3","SLC1A3",59.572,5.4033,2.2,1,1,1,0.963,1.063,0.962,1.148,0.993,0.887,1.013,0.919,"plasma membrane\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0043090 amino acid import; GO:0032989 cellular component morphogenesis; GO:0044237 cellular metabolic process; GO:0009084 glutamine family amino acid biosynthetic process; GO:0050877 neurological system process; GO:0007610 behavior; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0009449 gamma-aminobutyric acid biosynthetic process; GO:1901607 alpha-amino acid biosynthetic process; GO:0032787 monocarboxylic acid metabolic process; GO:0031223 auditory behavior; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0007399 nervous system development; GO:0006537 glutamate biosynthetic process; GO:0048699 generation of neurons; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0046942 carboxylic acid transport; GO:0098657 import into cell; GO:0032501 multicellular organismal process; GO:0000902 cell morphogenesis; GO:0006810 transport; GO:0007267 cell-cell signaling; GO:0044710 single-organism metabolic process; GO:0021675 nerve development; GO:0044708 single-organism behavior; GO:0043436 oxoacid metabolic process; GO:0014047 glutamate secretion; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0034220 ion transmembrane transport; GO:0009628 response to abiotic stimulus; GO:0015807 L-amino acid transport; GO:0009653 anatomical structure morphogenesis; GO:0042493 response to drug; GO:1902475 L-alpha-amino acid transmembrane transport; GO:0010996 response to auditory stimulus; GO:1902578 single-organism localization; GO:1903825 organic acid transmembrane transport; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0006865 amino acid transport; GO:0007275 multicellular organism development; GO:0050885 neuromuscular process controlling balance; GO:0008652 cellular amino acid biosynthetic process; GO:0009416 response to light stimulus; GO:0006950 response to stress; GO:0044711 single-organism biosynthetic process; GO:0048731 system development; GO:0050804 modulation of synaptic transmission; GO:0071702 organic substance transport; GO:1901605 alpha-amino acid metabolic process; GO:0044238 primary metabolic process; GO:0015849 organic acid transport; GO:1901576 organic substance biosynthetic process; GO:0089711 L-glutamate transmembrane transport; GO:0055085 transmembrane transport; GO:0030182 neuron differentiation; GO:0099536 synaptic signaling; GO:0006811 ion transport; GO:0044283 small molecule biosynthetic process; GO:0006835 dicarboxylic acid transport; GO:0007605 sensory perception of sound; GO:0007268 chemical synaptic transmission; GO:0051179 localization; GO:0050905 neuromuscular process; GO:0072330 monocarboxylic acid biosynthetic process; GO:1901564 organonitrogen compound metabolic process; GO:0070779 D-aspartate import; GO:0046717 acid secretion; GO:0001505 regulation of neurotransmitter levels; GO:0016053 organic acid biosynthetic process; GO:0023051 regulation of signaling; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0009058 biosynthetic process; GO:0051234 establishment of localization; GO:0009611 response to wounding; GO:0050806 positive regulation of synaptic transmission; GO:0010646 regulation of cell communication; GO:0006520 cellular amino acid metabolic process; GO:0007154 cell communication; GO:0009314 response to radiation; GO:0098916 anterograde trans-synaptic signaling; GO:1905039 carboxylic acid transmembrane transport; GO:0032502 developmental process; GO:0007600 sensory perception; GO:0070777 D-aspartate transport; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0042940 D-amino acid transport; GO:0015800 acidic amino acid transport; GO:0043650 dicarboxylic acid biosynthetic process; GO:0046394 carboxylic acid biosynthetic process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032940 secretion by cell; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:0050954 sensory perception of mechanical stimulus; GO:0016043 cellular component organization; GO:0043648 dicarboxylic acid metabolic process; GO:0046677 response to antibiotic; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0098656 anion transmembrane transport; GO:0071704 organic substance metabolic process; GO:0000904 cell morphogenesis involved in differentiation; GO:0009612 response to mechanical stimulus; GO:0030154 cell differentiation; GO:0009448 gamma-aminobutyric acid metabolic process; GO:0023056 positive regulation of signaling; GO:0006536 glutamate metabolic process; GO:0099537 trans-synaptic signaling; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:0007638 mechanosensory behavior; GO:0009064 glutamine family amino acid metabolic process; GO:0003008 system process; GO:0015810 aspartate transport; GO:0006807 nitrogen compound metabolic process; GO:0003333 amino acid transmembrane transport; GO:0015813 L-glutamate transport; GO:0048518 positive regulation of biological process; GO:0001504 neurotransmitter uptake; GO:0044249 cellular biosynthetic process; GO:0006820 anion transport; GO:0015711 organic anion transport; GO:0015740 C4-dicarboxylate transport; GO:0044767 single-organism developmental process; GO:0051938 L-glutamate import; GO:0019752 carboxylic acid metabolic process; GO:0021545 cranial nerve development; GO:0043092 L-amino acid import; GO:0071705 nitrogen compound transport; GO:0006836 neurotransmitter transport; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0042995 cell projection; GO:0071944 cell periphery; GO:0043025 neuronal cell body; GO:0031224 intrinsic component of membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0036477 somatodendritic compartment; GO:0044464 cell part; GO:0044425 membrane part; GO:0043005 neuron projection; GO:0044297 cell body; GO:0009986 cell surface; GO:0097458 neuron part; ","GO:0015294 solute:cation symporter activity; GO:0016597 amino acid binding; GO:0015179 L-amino acid transmembrane transporter activity; GO:0015370 solute:sodium symporter activity; GO:0022892 substrate-specific transporter activity; GO:0015077 monovalent inorganic cation transmembrane transporter activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0005313 L-glutamate transmembrane transporter activity; GO:0046873 metal ion transmembrane transporter activity; GO:0031406 carboxylic acid binding; GO:0005488 binding; GO:0043168 anion binding; GO:0022890 inorganic cation transmembrane transporter activity; GO:0015081 sodium ion transmembrane transporter activity; GO:0005215 transporter activity; GO:0005310 dicarboxylic acid transmembrane transporter activity; GO:0005342 organic acid transmembrane transporter activity; GO:0015291 secondary active transmembrane transporter activity; GO:0022804 active transmembrane transporter activity; GO:0015075 ion transmembrane transporter activity; GO:0015293 symporter activity; GO:0043167 ion binding; GO:0043177 organic acid binding; GO:0015172 acidic amino acid transmembrane transporter activity; GO:0016595 glutamate binding; GO:0008514 organic anion transmembrane transporter activity; GO:0005314 high-affinity glutamate transmembrane transporter activity; GO:0008324 cation transmembrane transporter activity; GO:0015171 amino acid transmembrane transporter activity; GO:0036094 small molecule binding; GO:0008509 anion transmembrane transporter activity; GO:0022857 transmembrane transporter activity; GO:0046943 carboxylic acid transmembrane transporter activity; ","K05614","SLC1A3; solute carrier family 1 (glial high affinity glutamate transporter), member 3","hsa04724 Glutamatergic synapse - Homo sapiens (human); "]
["P43007","Neutral amino acid transporter A OS=Homo sapiens OX=9606 GN=SLC1A4","SLC1A4",55.722,4.963,2.1,1,2,1,0.962,0.954,0.964,1.112,1.01,1.004,1.085,0.136,"plasma membrane\r","GO:0044700 single organism signaling; GO:0032329 serine transport; GO:0098661 inorganic anion transmembrane transport; GO:0015826 threonine transport; GO:0072337 modified amino acid transport; GO:0034220 ion transmembrane transport; GO:0015824 proline transport; GO:0015807 L-amino acid transport; GO:0044699 single-organism process; GO:0006821 chloride transport; GO:0007270 neuron-neuron synaptic transmission; GO:0050877 neurological system process; GO:0098656 anion transmembrane transport; GO:1902476 chloride transmembrane transport; GO:0051234 establishment of localization; GO:0006868 glutamine transport; GO:0032328 alanine transport; GO:0007154 cell communication; GO:1902578 single-organism localization; GO:1903825 organic acid transmembrane transport; GO:0006812 cation transport; GO:0015825 L-serine transport; GO:0050890 cognition; GO:0099537 trans-synaptic signaling; GO:0006865 amino acid transport; GO:0098916 anterograde trans-synaptic signaling; GO:0035249 synaptic transmission, glutamatergic; GO:0009987 cellular process; GO:1905039 carboxylic acid transmembrane transport; GO:0044765 single-organism transport; GO:0072348 sulfur compound transport; GO:0098655 cation transmembrane transport; GO:0003008 system process; GO:0098660 inorganic ion transmembrane transport; GO:0044763 single-organism cellular process; GO:0000101 sulfur amino acid transport; GO:0071702 organic substance transport; GO:0034589 hydroxyproline transport; GO:0003333 amino acid transmembrane transport; GO:0023052 signaling; GO:0046942 carboxylic acid transport; GO:0015849 organic acid transport; GO:0032501 multicellular organismal process; GO:0006820 anion transport; GO:0006810 transport; GO:0055085 transmembrane transport; GO:0035524 proline transmembrane transport; GO:0015711 organic anion transport; GO:0015808 L-alanine transport; GO:0007267 cell-cell signaling; GO:0099536 synaptic signaling; GO:0006811 ion transport; GO:0007268 chemical synaptic transmission; GO:0015804 neutral amino acid transport; GO:0051179 localization; GO:0071705 nitrogen compound transport; GO:0015698 inorganic anion transport; GO:0015811 L-cystine transport; ","GO:0016020 membrane; GO:0030425 dendrite; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0043025 neuronal cell body; GO:0031224 intrinsic component of membrane; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0048770 pigment granule; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0099513 polymeric cytoskeletal fiber; GO:0042995 cell projection; GO:0031226 intrinsic component of plasma membrane; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0042470 melanosome; GO:0044446 intracellular organelle part; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0099081 supramolecular polymer; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0044459 plasma membrane part; GO:0045111 intermediate filament cytoskeleton; GO:0005882 intermediate filament; GO:0009986 cell surface; GO:0044297 cell body; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0015179 L-amino acid transmembrane transporter activity; GO:0022803 passive transmembrane transporter activity; GO:0015186 L-glutamine transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0022858 alanine transmembrane transporter activity; GO:0015194 L-serine transmembrane transporter activity; GO:0015267 channel activity; GO:0015103 inorganic anion transmembrane transporter activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0015193 L-proline transmembrane transporter activity; GO:0034590 L-hydroxyproline transmembrane transporter activity; GO:0072349 modified amino acid transmembrane transporter activity; GO:0015175 neutral amino acid transmembrane transporter activity; GO:0005216 ion channel activity; GO:0000099 sulfur amino acid transmembrane transporter activity; GO:0015184 L-cystine transmembrane transporter activity; GO:0005215 transporter activity; GO:0005342 organic acid transmembrane transporter activity; GO:0015291 secondary active transmembrane transporter activity; GO:0022804 active transmembrane transporter activity; GO:0015075 ion transmembrane transporter activity; GO:1905361 L-serine transporter activity; GO:0015293 symporter activity; GO:0022889 serine transmembrane transporter activity; GO:0005253 anion channel activity; GO:0015195 L-threonine transmembrane transporter activity; GO:0005254 chloride channel activity; GO:0015108 chloride transmembrane transporter activity; GO:1901682 sulfur compound transmembrane transporter activity; GO:0022838 substrate-specific channel activity; GO:0015180 L-alanine transmembrane transporter activity; GO:0008514 organic anion transmembrane transporter activity; GO:0008324 cation transmembrane transporter activity; GO:0022857 transmembrane transporter activity; GO:0046943 carboxylic acid transmembrane transporter activity; GO:0008509 anion transmembrane transporter activity; GO:0015171 amino acid transmembrane transporter activity; ","K05615"]
["P43121","Cell surface glycoprotein MUC18 OS=Homo sapiens OX=9606 GN=MCAM","MCAM",71.607,59.912,18.1,11,20,11,1.177,1.151,1.211,0.909,0.786,0.835,0.715,1.64E-3,"extr_plas\r","GO:0050794 regulation of cellular process; GO:0072359 circulatory system development; GO:0061042 vascular wound healing; GO:0044707 single-multicellular organism process; GO:0030335 positive regulation of cell migration; GO:0060055 angiogenesis involved in wound healing; GO:0001568 blood vessel development; GO:0040017 positive regulation of locomotion; GO:0044699 single-organism process; GO:2000147 positive regulation of cell motility; GO:0050896 response to stimulus; GO:0009611 response to wounding; GO:0022610 biological adhesion; GO:0009653 anatomical structure morphogenesis; GO:0001525 angiogenesis; GO:2000145 regulation of cell motility; GO:0032879 regulation of localization; GO:0007155 cell adhesion; GO:0048514 blood vessel morphogenesis; GO:0007275 multicellular organism development; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0032502 developmental process; GO:0003094 glomerular filtration; GO:0003008 system process; GO:0006950 response to stress; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0003014 renal system process; GO:0001944 vasculature development; GO:0048522 positive regulation of cellular process; GO:0072358 cardiovascular system development; GO:0030334 regulation of cell migration; GO:0051272 positive regulation of cellular component movement; GO:0048518 positive regulation of biological process; GO:0032501 multicellular organismal process; GO:0050789 regulation of biological process; GO:0042060 wound healing; GO:0044767 single-organism developmental process; GO:0040012 regulation of locomotion; GO:0048856 anatomical structure development; GO:0097205 renal filtration; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0009897 external side of plasma membrane; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0070161 anchoring junction; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0005925 focal adhesion; GO:0044459 plasma membrane part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:0030055 cell-substrate junction; GO:0009986 cell surface; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0098552 side of membrane; ","GO:0005515 protein binding; GO:0005488 binding; ","K06534",null,null,"IPR003598; IPR007110; IPR013783; IPR013162; IPR013106; IPR003599; IPR013151; ","\"Immunoglobulin subtype 2; Immunoglobulin-like domain; Immunoglobulin-like fold; CD80-like, immunoglobulin C2-set; Immunoglobulin V-set domain; Immunoglobulin subtype; Immunoglobulin; \"\r"]
["P43243","Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3","MATR3",94.622,106.33,21.1,17,22,17,0.878,0.901,0.911,1.072,1.105,1.075,1.209,0.000201,"nucleus\r","GO:0019222 regulation of metabolic process; GO:0010468 regulation of gene expression; GO:0050789 regulation of biological process; GO:0010608 posttranscriptional regulation of gene expression; GO:0060255 regulation of macromolecule metabolic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0031090 organelle membrane; GO:0005635 nuclear envelope; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031974 membrane-enclosed lumen; GO:0031965 nuclear membrane; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0031975 envelope; GO:0016363 nuclear matrix; GO:0019866 organelle inner membrane; GO:0034399 nuclear periphery; GO:0043227 membrane-bounded organelle; GO:0005637 nuclear inner membrane; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:1901265 nucleoside phosphate binding; GO:0046914 transition metal ion binding; GO:0005488 binding; GO:0043167 ion binding; GO:0003676 nucleic acid binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0008270 zinc ion binding; GO:0005198 structural molecule activity; GO:0036094 small molecule binding; ","K13213",null,null,"IPR000504; IPR003604; IPR000690; IPR012677; ","\"RNA recognition motif domain; Zinc finger, U1-type; Zinc finger, C2H2-type matrin; Nucleotide-binding alpha-beta plait domain; \"\r"]
["P43304","Glycerol-3-phosphate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GPD2","GPD2",80.852,79.397,19.9,15,28,15,1.019,1.016,0.988,0.96,0.988,1.025,0.983,0.472,"mitochondria\r","GO:0019319 hexose biosynthetic process; GO:0006066 alcohol metabolic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0006006 glucose metabolic process; GO:0008152 metabolic process; GO:0006094 gluconeogenesis; GO:0044262 cellular carbohydrate metabolic process; GO:0006629 lipid metabolic process; GO:0032502 developmental process; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0052646 alditol phosphate metabolic process; GO:0044763 single-organism cellular process; GO:0006072 glycerol-3-phosphate metabolic process; GO:0005975 carbohydrate metabolic process; GO:0032501 multicellular organismal process; GO:0016052 carbohydrate catabolic process; GO:0019405 alditol catabolic process; GO:1901575 organic substance catabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0048513 animal organ development; GO:0044710 single-organism metabolic process; GO:0048856 anatomical structure development; GO:0044707 single-multicellular organism process; GO:0043010 camera-type eye development; GO:0016051 carbohydrate biosynthetic process; GO:1901615 organic hydroxy compound metabolic process; GO:0044275 cellular carbohydrate catabolic process; GO:0006071 glycerol metabolic process; GO:0046364 monosaccharide biosynthetic process; GO:0046164 alcohol catabolic process; GO:0071704 organic substance metabolic process; GO:0001654 eye development; GO:1901616 organic hydroxy compound catabolic process; GO:0035264 multicellular organism growth; GO:0005996 monosaccharide metabolic process; GO:0044248 cellular catabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0019400 alditol metabolic process; GO:0019563 glycerol catabolic process; GO:0044724 single-organism carbohydrate catabolic process; GO:0044711 single-organism biosynthetic process; GO:0044712 single-organism catabolic process; GO:0048731 system development; GO:0044282 small molecule catabolic process; GO:0044238 primary metabolic process; GO:0019751 polyol metabolic process; GO:1901576 organic substance biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0044767 single-organism developmental process; GO:0044283 small molecule biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0007423 sensory organ development; GO:0048589 developmental growth; GO:0009056 catabolic process; GO:0040007 growth; GO:0046174 polyol catabolic process; GO:0019318 hexose metabolic process; ","GO:0016020 membrane; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0031090 organelle membrane; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005740 mitochondrial envelope; GO:1902494 catalytic complex; GO:0005622 intracellular; GO:0044464 cell part; GO:0031975 envelope; GO:1990204 oxidoreductase complex; GO:0019866 organelle inner membrane; GO:0009331 glycerol-3-phosphate dehydrogenase complex; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0016614 oxidoreductase activity, acting on CH-OH group of donors; GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor; GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005509 calcium ion binding; GO:0004368 glycerol-3-phosphate dehydrogenase activity; GO:0052591 sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity; GO:0016491 oxidoreductase activity; ","K00111","glpA; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3]","hsa00564 Glycerophospholipid metabolism - Homo sapiens (human); ","IPR006076; IPR031656; IPR002048; IPR011992; IPR023753; ","\"FAD dependent oxidoreductase; Alpha-glycerophosphate oxidase, C-terminal; EF-hand domain; EF-hand domain pair; FAD/NAD(P)-binding domain; \"\r"]
["P43487","Ran-specific GTPase-activating protein OS=Homo sapiens OX=9606 GN=RANBP1","RANBP1",23.31,53.307,45.8,7,11,7,0.915,0.86,0.924,1.081,1.074,1.085,1.2,0.015,"cytoplasm\r","GO:0044700 single organism signaling; GO:0050658 RNA transport; GO:0072594 establishment of protein localization to organelle; GO:0017038 protein import; GO:0051785 positive regulation of nuclear division; GO:0044699 single-organism process; GO:0051169 nuclear transport; GO:0051168 nuclear export; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0010564 regulation of cell cycle process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0051130 positive regulation of cellular component organization; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0051783 regulation of nuclear division; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0050657 nucleic acid transport; GO:0015931 nucleobase-containing compound transport; GO:0044093 positive regulation of molecular function; GO:0044770 cell cycle phase transition; GO:0033365 protein localization to organelle; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0051493 regulation of cytoskeleton organization; GO:0006606 protein import into nucleus; GO:0008104 protein localization; GO:0044419 interspecies interaction between organisms; GO:0033036 macromolecule localization; GO:0090068 positive regulation of cell cycle process; GO:0051726 regulation of cell cycle; GO:0044765 single-organism transport; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0046604 positive regulation of mitotic centrosome separation; GO:0007088 regulation of mitotic nuclear division; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0023052 signaling; GO:1902582 single-organism intracellular transport; GO:0051704 multi-organism process; GO:0045840 positive regulation of mitotic nuclear division; GO:0006810 transport; GO:0032886 regulation of microtubule-based process; GO:1901575 organic substance catabolic process; GO:0000226 microtubule cytoskeleton organization; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:0045931 positive regulation of mitotic cell cycle; GO:0010638 positive regulation of organelle organization; GO:0030163 protein catabolic process; GO:0050790 regulation of catalytic activity; GO:0046602 regulation of mitotic centrosome separation; GO:0044260 cellular macromolecule metabolic process; GO:0043087 regulation of GTPase activity; GO:0065009 regulation of molecular function; GO:0006913 nucleocytoplasmic transport; GO:0046605 regulation of centrosome cycle; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0007346 regulation of mitotic cell cycle; GO:0044257 cellular protein catabolic process; GO:1902593 single-organism nuclear import; GO:0044267 cellular protein metabolic process; GO:0007051 spindle organization; GO:0050896 response to stimulus; GO:1903047 mitotic cell cycle process; GO:0051236 establishment of RNA localization; GO:0071704 organic substance metabolic process; GO:1902578 single-organism localization; GO:0051345 positive regulation of hydrolase activity; GO:0016032 viral process; GO:0006886 intracellular protein transport; GO:0044744 protein targeting to nucleus; GO:0044248 cellular catabolic process; GO:1902580 single-organism cellular localization; GO:0006508 proteolysis; GO:0034613 cellular protein localization; GO:0000082 G1/S transition of mitotic cell cycle; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0044772 mitotic cell cycle phase transition; GO:0045787 positive regulation of cell cycle; GO:0043632 modification-dependent macromolecule catabolic process; GO:0070507 regulation of microtubule cytoskeleton organization; GO:0044265 cellular macromolecule catabolic process; GO:0051495 positive regulation of cytoskeleton organization; GO:0044843 cell cycle G1/S phase transition; GO:0019941 modification-dependent protein catabolic process; GO:0043547 positive regulation of GTPase activity; GO:0046607 positive regulation of centrosome cycle; GO:0006403 RNA localization; GO:0006405 RNA export from nucleus; GO:0033043 regulation of organelle organization; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0007017 microtubule-based process; GO:0051641 cellular localization; GO:0043085 positive regulation of catalytic activity; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0051170 nuclear import; GO:0006996 organelle organization; GO:0009057 macromolecule catabolic process; GO:0051128 regulation of cellular component organization; GO:0022402 cell cycle process; GO:0051179 localization; GO:0034504 protein localization to nucleus; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0071705 nitrogen compound transport; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005635 nuclear envelope; GO:0044430 cytoskeletal part; GO:0005737 cytoplasm; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005815 microtubule organizing center; GO:0005634 nucleus; GO:0015630 microtubule cytoskeleton; GO:0005813 centrosome; GO:0005622 intracellular; GO:0044464 cell part; GO:0031975 envelope; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0031267 small GTPase binding; GO:0005092 GDP-dissociation inhibitor activity; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0030695 GTPase regulator activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0050839 cell adhesion molecule binding; GO:0030234 enzyme regulator activity; GO:0017016 Ras GTPase binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0008536 Ran GTPase binding; GO:0051020 GTPase binding; GO:0019899 enzyme binding; GO:0008047 enzyme activator activity; GO:0005096 GTPase activator activity; ","K15306","RANBP1; Ran-binding protein 1","hsa05166 HTLV-I infection - Homo sapiens (human); hsa05203 Viral carcinogenesis - Homo sapiens (human); ","IPR000156; IPR011993; ","Ran binding domain; PH domain-like; \r"]
["P43686","26S proteasome regulatory subunit 6B OS=Homo sapiens OX=9606 GN=PSMC4","PSMC4",47.366,93.651,32.3,16,21,16,0.928,0.893,0.918,1.106,1.091,1.099,1.203,1.03E-4,"cytoplasm\r","GO:0044700 single organism signaling; GO:0010608 posttranscriptional regulation of gene expression; GO:0043009 chordate embryonic development; GO:0051443 positive regulation of ubiquitin-protein transferase activity; GO:0009891 positive regulation of biosynthetic process; GO:0031347 regulation of defense response; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:1903364 positive regulation of cellular protein catabolic process; GO:0008152 metabolic process; GO:0044093 positive regulation of molecular function; GO:0090263 positive regulation of canonical Wnt signaling pathway; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0016055 Wnt signaling pathway; GO:0009790 embryo development; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0006521 regulation of cellular amino acid metabolic process; GO:0080090 regulation of primary metabolic process; GO:0010972 negative regulation of G2/M transition of mitotic cell cycle; GO:0044763 single-organism cellular process; GO:0060828 regulation of canonical Wnt signaling pathway; GO:0043086 negative regulation of catalytic activity; GO:0033209 tumor necrosis factor-mediated signaling pathway; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0000165 MAPK cascade; GO:0019884 antigen processing and presentation of exogenous antigen; GO:1901575 organic substance catabolic process; GO:0007267 cell-cell signaling; GO:0002223 stimulatory C-type lectin receptor signaling pathway; GO:0030163 protein catabolic process; GO:0061136 regulation of proteasomal protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0060071 Wnt signaling pathway, planar cell polarity pathway; GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0016310 phosphorylation; GO:0044707 single-multicellular organism process; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0043487 regulation of RNA stability; GO:0000209 protein polyubiquitination; GO:0023057 negative regulation of signaling; GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly; GO:0010648 negative regulation of cell communication; GO:0009889 regulation of biosynthetic process; GO:0009896 positive regulation of catabolic process; GO:0043620 regulation of DNA-templated transcription in response to stress; GO:0070482 response to oxygen levels; GO:0044248 cellular catabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0042176 regulation of protein catabolic process; GO:0038093 Fc receptor signaling pathway; GO:0050778 positive regulation of immune response; GO:0023014 signal transduction by protein phosphorylation; GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; GO:0006950 response to stress; GO:0016567 protein ubiquitination; GO:2000142 regulation of DNA-templated transcription, initiation; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:1903321 negative regulation of protein modification by small protein conjugation or removal; GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter; GO:0031398 positive regulation of protein ubiquitination; GO:0032446 protein modification by small protein conjugation; GO:0031325 positive regulation of cellular metabolic process; GO:0030177 positive regulation of Wnt signaling pathway; GO:1904668 positive regulation of ubiquitin protein ligase activity; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0043412 macromolecule modification; GO:0070646 protein modification by small protein removal; GO:0009968 negative regulation of signal transduction; GO:0031331 positive regulation of cellular catabolic process; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0031400 negative regulation of protein modification process; GO:0006796 phosphate-containing compound metabolic process; GO:0031396 regulation of protein ubiquitination; GO:2001141 regulation of RNA biosynthetic process; GO:0045930 negative regulation of mitotic cell cycle; GO:0007165 signal transduction; GO:2000144 positive regulation of DNA-templated transcription, initiation; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0034612 response to tumor necrosis factor; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0051726 regulation of cell cycle; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0034097 response to cytokine; GO:0031326 regulation of cellular biosynthetic process; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0198738 cell-cell signaling by wnt; GO:0010565 regulation of cellular ketone metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0036211 protein modification process; GO:0090175 regulation of establishment of planar polarity; GO:0045786 negative regulation of cell cycle; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:1901988 negative regulation of cell cycle phase transition; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0010498 proteasomal protein catabolic process; GO:0071704 organic substance metabolic process; GO:0045862 positive regulation of proteolysis; GO:2000027 regulation of organ morphogenesis; GO:0006468 protein phosphorylation; GO:0023056 positive regulation of signaling; GO:0001666 response to hypoxia; GO:0002757 immune response-activating signal transduction; GO:0010647 positive regulation of cell communication; GO:0071453 cellular response to oxygen levels; GO:0019221 cytokine-mediated signaling pathway; GO:0031397 negative regulation of protein ubiquitination; GO:0006355 regulation of transcription, DNA-templated; GO:0019941 modification-dependent protein catabolic process; GO:0035556 intracellular signal transduction; GO:0009792 embryo development ending in birth or egg hatching; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:1901800 positive regulation of proteasomal protein catabolic process; GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia; GO:1902749 regulation of cell cycle G2/M phase transition; GO:0043488 regulation of mRNA stability; GO:0043085 positive regulation of catalytic activity; GO:0019882 antigen processing and presentation; GO:0050852 T cell receptor signaling pathway; GO:0002684 positive regulation of immune system process; GO:0038095 Fc-epsilon receptor signaling pathway; GO:0051248 negative regulation of protein metabolic process; GO:0022402 cell cycle process; GO:1902750 negative regulation of cell cycle G2/M phase transition; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0044089 positive regulation of cellular component biogenesis; GO:0060260 regulation of transcription initiation from RNA polymerase II promoter; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0002220 innate immune response activating cell surface receptor signaling pathway; GO:0007166 cell surface receptor signaling pathway; GO:0036503 ERAD pathway; GO:0071345 cellular response to cytokine stimulus; GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0051347 positive regulation of transferase activity; GO:1903362 regulation of cellular protein catabolic process; GO:0002758 innate immune response-activating signal transduction; GO:0031329 regulation of cellular catabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0009894 regulation of catabolic process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:1903506 regulation of nucleic acid-templated transcription; GO:2000058 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0010948 negative regulation of cell cycle process; GO:0001701 in utero embryonic development; GO:0032269 negative regulation of cellular protein metabolic process; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0002682 regulation of immune system process; GO:0031145 anaphase-promoting complex-dependent catabolic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0007346 regulation of mitotic cell cycle; GO:0034976 response to endoplasmic reticulum stress; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:0051239 regulation of multicellular organismal process; GO:0031349 positive regulation of defense response; GO:0010628 positive regulation of gene expression; GO:1901987 regulation of cell cycle phase transition; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0010389 regulation of G2/M transition of mitotic cell cycle; GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:0038061 NIK/NF-kappaB signaling; GO:0071456 cellular response to hypoxia; GO:0002253 activation of immune response; GO:0051254 positive regulation of RNA metabolic process; GO:0001824 blastocyst development; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1904666 regulation of ubiquitin protein ligase activity; GO:0055085 transmembrane transport; GO:0051247 positive regulation of protein metabolic process; GO:0051438 regulation of ubiquitin-protein transferase activity; GO:0030111 regulation of Wnt signaling pathway; GO:0006793 phosphorus metabolic process; GO:0036293 response to decreased oxygen levels; GO:0031328 positive regulation of cellular biosynthetic process; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process; GO:0051444 negative regulation of ubiquitin-protein transferase activity; GO:0090090 negative regulation of canonical Wnt signaling pathway; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0035567 non-canonical Wnt signaling pathway; GO:1905330 regulation of morphogenesis of an epithelium; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0030433 ubiquitin-dependent ERAD pathway; GO:1901991 negative regulation of mitotic cell cycle phase transition; GO:0045088 regulation of innate immune response; GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I; GO:0031334 positive regulation of protein complex assembly; GO:0070887 cellular response to chemical stimulus; GO:0050851 antigen receptor-mediated signaling pathway; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0030178 negative regulation of Wnt signaling pathway; GO:0048002 antigen processing and presentation of peptide antigen; GO:0048522 positive regulation of cellular process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0051348 negative regulation of transferase activity; GO:0070647 protein modification by small protein conjugation or removal; GO:0042221 response to chemical; GO:0043254 regulation of protein complex assembly; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0019222 regulation of metabolic process; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:1904667 negative regulation of ubiquitin protein ligase activity; GO:0002218 activation of innate immune response; GO:0071356 cellular response to tumor necrosis factor; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044087 regulation of cellular component biogenesis; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0016579 protein deubiquitination; GO:1903322 positive regulation of protein modification by small protein conjugation or removal; GO:0006508 proteolysis; GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:0009987 cellular process; GO:0033238 regulation of cellular amine metabolic process; GO:0043632 modification-dependent macromolecule catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0045089 positive regulation of innate immune response; GO:0044712 single-organism catabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition; GO:0031401 positive regulation of protein modification process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0009057 macromolecule catabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0009967 positive regulation of signal transduction; GO:0051128 regulation of cellular component organization; GO:0045732 positive regulation of protein catabolic process; GO:0036294 cellular response to decreased oxygen levels; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005838 proteasome regulatory particle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:1905369 endopeptidase complex; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0022624 proteasome accessory complex; GO:0005622 intracellular; GO:0044464 cell part; GO:0044445 cytosolic part; GO:1905368 peptidase complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0000502 proteasome complex; GO:0044446 intracellular organelle part; GO:0016234 inclusion body; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0031595 nuclear proteasome complex; GO:0045202 synapse; GO:0008540 proteasome regulatory particle, base subcomplex; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0031597 cytosolic proteasome complex; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0016887 ATPase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0036402 proteasome-activating ATPase activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0042623 ATPase activity, coupled; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0017025 TBP-class protein binding; GO:0008134 transcription factor binding; GO:0036094 small molecule binding; ","K03063","PSMC4; 26S proteasome regulatory subunit T3","hsa03050 Proteasome - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); ","IPR003593; IPR003959; IPR027417; ","\"AAA+ ATPase domain; ATPase, AAA-type, core; P-loop containing nucleoside triphosphate hydrolase; \"\r"]
["P45880","Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2","VDAC2",31.566,111.82,33.3,10,24,10,0.982,0.952,1.006,1.001,1.033,1.091,1.063,0.112,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0010941 regulation of cell death; GO:0043069 negative regulation of programmed cell death; GO:0009968 negative regulation of signal transduction; GO:0051129 negative regulation of cellular component organization; GO:0023051 regulation of signaling; GO:0044070 regulation of anion transport; GO:0043067 regulation of programmed cell death; GO:0044087 regulation of cellular component biogenesis; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0051234 establishment of localization; GO:2001233 regulation of apoptotic signaling pathway; GO:0023057 negative regulation of signaling; GO:0010646 regulation of cell communication; GO:0010648 negative regulation of cell communication; GO:2001243 negative regulation of intrinsic apoptotic signaling pathway; GO:0043066 negative regulation of apoptotic process; GO:0032879 regulation of localization; GO:0032271 regulation of protein polymerization; GO:0009966 regulation of signal transduction; GO:0031333 negative regulation of protein complex assembly; GO:1902531 regulation of intracellular signal transduction; GO:0051049 regulation of transport; GO:0043269 regulation of ion transport; GO:0048585 negative regulation of response to stimulus; GO:1903959 regulation of anion transmembrane transport; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0006820 anion transport; GO:0006810 transport; GO:0034762 regulation of transmembrane transport; GO:0055085 transmembrane transport; GO:0043254 regulation of protein complex assembly; GO:0050789 regulation of biological process; GO:0034765 regulation of ion transmembrane transport; GO:1902532 negative regulation of intracellular signal transduction; GO:0006811 ion transport; GO:0048583 regulation of response to stimulus; GO:2001242 regulation of intrinsic apoptotic signaling pathway; GO:0051128 regulation of cellular component organization; GO:0032272 negative regulation of protein polymerization; GO:0051179 localization; GO:0060548 negative regulation of cell death; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0019867 outer membrane; GO:0031090 organelle membrane; GO:0098857 membrane microdomain; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070382 exocytic vesicle; GO:0070062 extracellular exosome; GO:0008021 synaptic vesicle; GO:0043209 myelin sheath; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0098589 membrane region; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0097458 neuron part; GO:0043233 organelle lumen; GO:0005759 mitochondrial matrix; GO:0042645 mitochondrial nucleoid; GO:0031967 organelle envelope; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0031975 envelope; GO:0030133 transport vesicle; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0031966 mitochondrial membrane; GO:0009295 nucleoid; GO:0031410 cytoplasmic vesicle; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0031974 membrane-enclosed lumen; GO:0005740 mitochondrial envelope; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0044425 membrane part; GO:0098793 presynapse; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0019866 organelle inner membrane; GO:0031968 organelle outer membrane; GO:0045121 membrane raft; GO:0044456 synapse part; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0044429 mitochondrial part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0046930 pore complex; GO:0005741 mitochondrial outer membrane; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0016021 integral component of membrane; GO:0045202 synapse; GO:0043226 organelle; GO:0005634 nucleus; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0015075 ion transmembrane transporter activity; GO:0022803 passive transmembrane transporter activity; GO:0005253 anion channel activity; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0015267 channel activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0005244 voltage-gated ion channel activity; GO:0008308 voltage-gated anion channel activity; GO:0022829 wide pore channel activity; GO:0022838 substrate-specific channel activity; GO:0005488 binding; GO:0015288 porin activity; GO:0022836 gated channel activity; GO:0005216 ion channel activity; GO:0022832 voltage-gated channel activity; GO:0008509 anion transmembrane transporter activity; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; GO:0036094 small molecule binding; ","K15040","VDAC2; voltage-dependent anion channel protein 2","hsa04218 Cellular senescence - Homo sapiens (human); hsa04216 Ferroptosis - Homo sapiens (human); hsa04979 Cholesterol metabolism - Homo sapiens (human); hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human); hsa04217 Necroptosis - Homo sapiens (human); hsa04020 Calcium signaling pathway - Homo sapiens (human); hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human); hsa05166 HTLV-I infection - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); ","IPR023614; ","Porin domain; \r"]
["P45973","Chromobox protein homolog 5 OS=Homo sapiens OX=9606 GN=CBX5","CBX5",22.225,18.452,27.2,4,4,4,1.004,0.973,0.95,1.099,0.988,0.996,1.053,0.248,"nucleus\r","GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:0051253 negative regulation of RNA metabolic process; GO:0007599 hemostasis; GO:0045892 negative regulation of transcription, DNA-templated; GO:0009611 response to wounding; GO:2001141 regulation of RNA biosynthetic process; GO:0016032 viral process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0044419 interspecies interaction between organisms; GO:0009987 cellular process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0010468 regulation of gene expression; GO:0050878 regulation of body fluid levels; GO:0006355 regulation of transcription, DNA-templated; GO:0006950 response to stress; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0010629 negative regulation of gene expression; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0009892 negative regulation of metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0009890 negative regulation of biosynthetic process; GO:0050789 regulation of biological process; GO:0042060 wound healing; GO:1902679 negative regulation of RNA biosynthetic process; GO:0019222 regulation of metabolic process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0050817 coagulation; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0065007 biological regulation; ","GO:0000784 nuclear chromosome, telomeric region; GO:0000781 chromosome, telomeric region; GO:0032991 macromolecular complex; GO:0017053 transcriptional repressor complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0000792 heterochromatin; GO:0000118 histone deacetylase complex; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044454 nuclear chromosome part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0000790 nuclear chromatin; GO:0005721 pericentric heterochromatin; GO:0043227 membrane-bounded organelle; GO:0000776 kinetochore; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0010369 chromocenter; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005635 nuclear envelope; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0035097 histone methyltransferase complex; GO:0005730 nucleolus; GO:1990234 transferase complex; GO:0031618 nuclear pericentric heterochromatin; GO:0005720 nuclear heterochromatin; GO:0034708 methyltransferase complex; GO:0098687 chromosomal region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0000785 chromatin; GO:0031975 envelope; GO:0000775 chromosome, centromeric region; GO:0000228 nuclear chromosome; GO:0043234 protein complex; GO:0044428 nuclear part; ","GO:0042393 histone binding; GO:0042802 identical protein binding; GO:0042826 histone deacetylase binding; GO:0030674 protein binding, bridging; GO:0070491 repressing transcription factor binding; GO:0035064 methylated histone binding; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0046983 protein dimerization activity; GO:0060090 binding, bridging; GO:0005515 protein binding; GO:0003682 chromatin binding; GO:0008134 transcription factor binding; GO:0019899 enzyme binding; ","K11587",null,null,"IPR017984; IPR008251; IPR023780; IPR016197; IPR000953; ","Chromo domain subgroup; Chromo shadow domain; Chromo domain; Chromo domain-like; Chromo/chromo shadow domain; \r"]
["P45974","Ubiquitin carboxyl-terminal hydrolase 5 OS=Homo sapiens OX=9606 GN=USP5","USP5",95.785,140.71,28.2,21,32,21,1.001,0.955,0.972,1.028,0.996,1,1.033,0.129,"nucleus\r","GO:0050794 regulation of cellular process; GO:0070646 protein modification by small protein removal; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0032270 positive regulation of cellular protein metabolic process; GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0031331 positive regulation of cellular catabolic process; GO:0044267 cellular protein metabolic process; GO:0016579 protein deubiquitination; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:1903364 positive regulation of cellular protein catabolic process; GO:0008152 metabolic process; GO:0045862 positive regulation of proteolysis; GO:0009893 positive regulation of metabolic process; GO:0009896 positive regulation of catabolic process; GO:0044248 cellular catabolic process; GO:0006508 proteolysis; GO:0042176 regulation of protein catabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0009987 cellular process; GO:1903362 regulation of cellular protein catabolic process; GO:0043632 modification-dependent macromolecule catabolic process; GO:0071108 protein K48-linked deubiquitination; GO:0044265 cellular macromolecule catabolic process; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0016567 protein ubiquitination; GO:0019941 modification-dependent protein catabolic process; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:1901800 positive regulation of proteasomal protein catabolic process; GO:0048522 positive regulation of cellular process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0030162 regulation of proteolysis; GO:0070647 protein modification by small protein conjugation or removal; GO:0031323 regulation of cellular metabolic process; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:1901575 organic substance catabolic process; GO:0051247 positive regulation of protein metabolic process; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0032446 protein modification by small protein conjugation; GO:0030163 protein catabolic process; GO:0051246 regulation of protein metabolic process; GO:0009057 macromolecule catabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0061136 regulation of proteasomal protein catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006464 cellular protein modification process; GO:0045732 positive regulation of protein catabolic process; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:0009056 catabolic process; GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process; GO:0065007 biological regulation; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0005764 lysosome; GO:0005737 cytoplasm; GO:0005773 vacuole; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005829 cytosol; GO:0005623 cell; GO:0044444 cytoplasmic part; GO:0000323 lytic vacuole; ","GO:0004843 thiol-dependent ubiquitin-specific protease activity; GO:0008233 peptidase activity; GO:0043167 ion binding; GO:0019783 ubiquitin-like protein-specific protease activity; GO:0005515 protein binding; GO:0008234 cysteine-type peptidase activity; GO:0016787 hydrolase activity; GO:0008270 zinc ion binding; GO:0032182 ubiquitin-like protein binding; GO:0004175 endopeptidase activity; GO:0036459 thiol-dependent ubiquitinyl hydrolase activity; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0101005 ubiquitinyl hydrolase activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0043130 ubiquitin binding; GO:0004197 cysteine-type endopeptidase activity; ","K11836",null,null,"IPR001607; IPR015940; IPR013083; IPR001394; IPR028889; IPR009060; ","\"Zinc finger, UBP-type; Ubiquitin-associated domain; Zinc finger, RING/FYVE/PHD-type; Peptidase C19, ubiquitin carboxyl-terminal hydrolase; Ubiquitin specific protease domain; UBA-like; \"\r"]
["P46063","ATP-dependent DNA helicase Q1 OS=Homo sapiens OX=9606 GN=RECQL","RECQL",73.457,58.084,20,12,16,12,1.006,0.87,0.91,1.064,1.082,1.049,1.147,0.0341,"cytoplasm\r","GO:0033554 cellular response to stress; GO:0016043 cellular component organization; GO:0000733 DNA strand renaturation; GO:0006725 cellular aromatic compound metabolic process; GO:0006259 DNA metabolic process; GO:0006302 double-strand break repair; GO:0032392 DNA geometric change; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0000724 double-strand break repair via homologous recombination; GO:0009987 cellular process; GO:0006310 DNA recombination; GO:0071103 DNA conformation change; GO:0051716 cellular response to stimulus; GO:0006950 response to stress; GO:0032508 DNA duplex unwinding; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0044238 primary metabolic process; GO:0006974 cellular response to DNA damage stimulus; GO:0006281 DNA repair; GO:0000725 recombinational repair; GO:0090304 nucleic acid metabolic process; GO:0051276 chromosome organization; GO:0006996 organelle organization; GO:0044260 cellular macromolecule metabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0008026 ATP-dependent helicase activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0009378 four-way junction helicase activity; GO:0016887 ATPase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0004003 ATP-dependent DNA helicase activity; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0043138 3'-5' DNA helicase activity; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0008094 DNA-dependent ATPase activity; GO:0003678 DNA helicase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003677 DNA binding; GO:0005524 ATP binding; GO:0070035 purine NTP-dependent helicase activity; GO:0097617 annealing activity; GO:0004386 helicase activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0036310 annealing helicase activity; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003676 nucleic acid binding; GO:0042623 ATPase activity, coupled; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0043140 ATP-dependent 3'-5' DNA helicase activity; GO:0036094 small molecule binding; ","K10899",null,null,"IPR011991; IPR011545; IPR027417; IPR014001; IPR032284; IPR001650; ","\"Winged helix-turn-helix DNA-binding domain; DEAD/DEAH box helicase domain; P-loop containing nucleoside triphosphate hydrolase; Helicase superfamily 1/2, ATP-binding domain; ATP-dependent DNA helicase RecQ, zinc-binding domain; Helicase, C-terminal; \"\r"]
["P46093","G-protein coupled receptor 4 OS=Homo sapiens OX=9606 GN=GPR4","GPR4",40.981,2.1123,1.9,1,1,1,0.638,0.71,1.679,0.653,null,1.318,0.977,0.975,"plasma membrane\r","GO:1904238 pericyte cell differentiation; GO:0044700 single organism signaling; GO:0051093 negative regulation of developmental process; GO:0072109 glomerular mesangium development; GO:0065008 regulation of biological quality; GO:0072503 cellular divalent inorganic cation homeostasis; GO:0060055 angiogenesis involved in wound healing; GO:0001568 blood vessel development; GO:0072144 glomerular mesangial cell development; GO:0023051 regulation of signaling; GO:0048869 cellular developmental process; GO:1902533 positive regulation of intracellular signal transduction; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0009611 response to wounding; GO:0001525 angiogenesis; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0055065 metal ion homeostasis; GO:0061448 connective tissue development; GO:0048514 blood vessel morphogenesis; GO:0051056 regulation of small GTPase mediated signal transduction; GO:0032502 developmental process; GO:2000181 negative regulation of blood vessel morphogenesis; GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway; GO:0060429 epithelium development; GO:0051716 cellular response to stimulus; GO:0002064 epithelial cell development; GO:0009888 tissue development; GO:0050801 ion homeostasis; GO:0055074 calcium ion homeostasis; GO:0044763 single-organism cellular process; GO:0098771 inorganic ion homeostasis; GO:0048522 positive regulation of cellular process; GO:0001944 vasculature development; GO:0019725 cellular homeostasis; GO:0046579 positive regulation of Ras protein signal transduction; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:1901343 negative regulation of vasculature development; GO:0006874 cellular calcium ion homeostasis; GO:0001655 urogenital system development; GO:0048513 animal organ development; GO:0016525 negative regulation of angiogenesis; GO:0050789 regulation of biological process; GO:0048583 regulation of response to stimulus; GO:0045765 regulation of angiogenesis; GO:0048856 anatomical structure development; GO:0072507 divalent inorganic cation homeostasis; GO:0030855 epithelial cell differentiation; GO:2000026 regulation of multicellular organismal development; GO:0050794 regulation of cellular process; GO:0072359 circulatory system development; GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway; GO:0044707 single-multicellular organism process; GO:0009628 response to abiotic stimulus; GO:0051480 regulation of cytosolic calcium ion concentration; GO:0030003 cellular cation homeostasis; GO:0061440 kidney vasculature development; GO:0046578 regulation of Ras protein signal transduction; GO:0072001 renal system development; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0055082 cellular chemical homeostasis; GO:0051239 regulation of multicellular organismal process; GO:0032835 glomerulus development; GO:0042592 homeostatic process; GO:0009653 anatomical structure morphogenesis; GO:0009268 response to pH; GO:0030154 cell differentiation; GO:0055080 cation homeostasis; GO:0023056 positive regulation of signaling; GO:0035025 positive regulation of Rho protein signal transduction; GO:0072006 nephron development; GO:0010647 positive regulation of cell communication; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0048878 chemical homeostasis; GO:0072008 glomerular mesangial cell differentiation; GO:0072143 mesangial cell development; GO:0001822 kidney development; GO:1902531 regulation of intracellular signal transduction; GO:0006950 response to stress; GO:0051057 positive regulation of small GTPase mediated signal transduction; GO:0048731 system development; GO:1901342 regulation of vasculature development; GO:0072358 cardiovascular system development; GO:0048518 positive regulation of biological process; GO:0072012 glomerulus vasculature development; GO:0061005 cell differentiation involved in kidney development; GO:0007186 G-protein coupled receptor signaling pathway; GO:0042060 wound healing; GO:0006873 cellular ion homeostasis; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0072007 mesangial cell differentiation; GO:0006875 cellular metal ion homeostasis; GO:0010447 response to acidic pH; GO:0009967 positive regulation of signal transduction; GO:0035850 epithelial cell differentiation involved in kidney development; GO:0048584 positive regulation of response to stimulus; GO:0061437 renal system vasculature development; GO:0007204 positive regulation of cytosolic calcium ion concentration; GO:0035023 regulation of Rho protein signal transduction; GO:0050793 regulation of developmental process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0031226 intrinsic component of plasma membrane; GO:0044459 plasma membrane part; GO:0044425 membrane part; GO:0044464 cell part; GO:0071944 cell periphery; GO:0031224 intrinsic component of membrane; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; ","GO:0038023 signaling receptor activity; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0004930 G-protein coupled receptor activity; GO:0004888 transmembrane signaling receptor activity; GO:0004871 signal transducer activity; GO:0099600 transmembrane receptor activity; ","K04312",null,null,"IPR017452; ","\"GPCR, rhodopsin-like, 7TM; \"\r"]
["P46199","Translation initiation factor IF-2, mitochondrial OS=Homo sapiens OX=9606 GN=MTIF2","MTIF2",81.316,4.1143,2.5,2,2,2,0.996,1.023,0.946,1.027,0.969,1.047,1.026,0.472,"mitochondria\r","GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0006518 peptide metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0010608 posttranscriptional regulation of gene expression; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:1903008 organelle disassembly; GO:0009058 biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0070124 mitochondrial translational initiation; GO:0044237 cellular metabolic process; GO:0032790 ribosome disassembly; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0071826 ribonucleoprotein complex subunit organization; GO:0009889 regulation of biosynthetic process; GO:0006413 translational initiation; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006412 translation; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0043043 peptide biosynthetic process; GO:0044763 single-organism cellular process; GO:0032984 macromolecular complex disassembly; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0032543 mitochondrial translation; GO:0043603 cellular amide metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0034248 regulation of cellular amide metabolic process; GO:1902589 single-organism organelle organization; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006996 organelle organization; GO:0051246 regulation of protein metabolic process; GO:0006417 regulation of translation; GO:0044260 cellular macromolecule metabolic process; GO:0022411 cellular component disassembly; GO:0006446 regulation of translational initiation; GO:0019222 regulation of metabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0071840 cellular component organization or biogenesis; GO:0032988 ribonucleoprotein complex disassembly; GO:0065007 biological regulation; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0043229 intracellular organelle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0003743 translation initiation factor activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0043024 ribosomal small subunit binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0003924 GTPase activity; GO:0043168 anion binding; GO:0019001 guanyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003723 RNA binding; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0008135 translation factor activity, RNA binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003676 nucleic acid binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0032561 guanyl ribonucleotide binding; GO:0043021 ribonucleoprotein complex binding; GO:0036094 small molecule binding; ","K02519",null,null,"IPR023115; IPR005225; IPR027417; IPR000795; IPR009000; ","\"Translation initiation factor IF- 2, domain 3; Small GTP-binding protein domain; P-loop containing nucleoside triphosphate hydrolase; Transcription factor, GTP-binding domain; Translation protein, beta-barrel domain; \"\r"]
["P46439","Glutathione S-transferase Mu 5 OS=Homo sapiens OX=9606 GN=GSTM5","GSTM5",25.674,16.665,49.1,11,25,2,1.223,1.174,1.145,0.864,0.881,0.746,0.703,0.00318,"cytoplasm\r","GO:0006790 sulfur compound metabolic process; GO:0006518 peptide metabolic process; GO:0044711 single-organism biosynthetic process; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0006807 nitrogen compound metabolic process; GO:0009058 biosynthetic process; GO:0043603 cellular amide metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:1901576 organic substance biosynthetic process; GO:0044237 cellular metabolic process; GO:0044272 sulfur compound biosynthetic process; GO:0044249 cellular biosynthetic process; GO:1901687 glutathione derivative biosynthetic process; GO:0071704 organic substance metabolic process; GO:1901685 glutathione derivative metabolic process; GO:0008152 metabolic process; GO:0006575 cellular modified amino acid metabolic process; GO:0044710 single-organism metabolic process; GO:0006749 glutathione metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009987 cellular process; GO:1901564 organonitrogen compound metabolic process; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0044444 cytoplasmic part; ","GO:0004364 glutathione transferase activity; GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups; GO:0005515 protein binding; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0016740 transferase activity; GO:0005488 binding; ","K00799","GST; glutathione S-transferase [EC:2.5.1.18]","hsa01524 Platinum drug resistance - Homo sapiens (human); hsa00480 Glutathione metabolism - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa05204 Chemical carcinogenesis - Homo sapiens (human); hsa00980 Metabolism of xenobiotics by cytochrome P450 - Homo sapiens (human); hsa05225 Hepatocellular carcinoma - Homo sapiens (human); hsa00983 Drug metabolism - other enzymes - Homo sapiens (human); hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human); hsa00982 Drug metabolism - cytochrome P450 - Homo sapiens (human); hsa05215 Prostate cancer - Homo sapiens (human); ","IPR004046; IPR010987; IPR004045; IPR012336; ","\"Glutathione S-transferase, C-terminal; Glutathione S-transferase, C-terminal-like; Glutathione S-transferase, N-terminal; Thioredoxin-like fold; \"\r"]
["P46777","60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5","RPL5",34.362,97.154,42.1,14,35,14,0.907,0.916,0.912,1.073,1.078,1.086,1.184,1.55E-6,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0072594 establishment of protein localization to organelle; GO:0006518 peptide metabolic process; GO:0022618 ribonucleoprotein complex assembly; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0042273 ribosomal large subunit biogenesis; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0051649 establishment of localization in cell; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0000027 ribosomal large subunit assembly; GO:0071826 ribonucleoprotein complex subunit organization; GO:0070972 protein localization to endoplasmic reticulum; GO:0022607 cellular component assembly; GO:0006364 rRNA processing; GO:0065003 macromolecular complex assembly; GO:0006413 translational initiation; GO:1901361 organic cyclic compound catabolic process; GO:0033365 protein localization to organelle; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0006412 translation; GO:0016072 rRNA metabolic process; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0072657 protein localization to membrane; GO:0043043 peptide biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0042254 ribosome biogenesis; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032774 RNA biosynthetic process; GO:0045047 protein targeting to ER; GO:0043603 cellular amide metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0016070 RNA metabolic process; GO:0006401 RNA catabolic process; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0019083 viral transcription; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0044267 cellular protein metabolic process; GO:0006613 cotranslational protein targeting to membrane; GO:0048519 negative regulation of biological process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0070925 organelle assembly; GO:0006139 nucleobase-containing compound metabolic process; GO:0016032 viral process; GO:0019080 viral gene expression; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0006886 intracellular protein transport; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0034613 cellular protein localization; GO:0009059 macromolecule biosynthetic process; GO:0090150 establishment of protein localization to membrane; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0034622 cellular macromolecular complex assembly; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0043933 macromolecular complex subunit organization; GO:0042255 ribosome assembly; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006996 organelle organization; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0051179 localization; GO:0009056 catabolic process; GO:0034660 ncRNA metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0071840 cellular component organization or biogenesis; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0005925 focal adhesion; GO:0070013 intracellular organelle lumen; GO:0044391 ribosomal subunit; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030055 cell-substrate junction; GO:0044445 cytosolic part; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0022626 cytosolic ribosome; GO:0043229 intracellular organelle; GO:0005840 ribosome; GO:0043232 intracellular non-membrane-bounded organelle; GO:0022625 cytosolic large ribosomal subunit; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0015934 large ribosomal subunit; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0008097 5S rRNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0005198 structural molecule activity; GO:0003735 structural constituent of ribosome; GO:0019843 rRNA binding; ","K02932","RP-L5e; large subunit ribosomal protein L5e","hsa03010 Ribosome - Homo sapiens (human); ","IPR025607; ","\"Ribosomal protein L5 eukaryotic/L18 archaeal, C-terminal; \"\r"]
["P46778","60S ribosomal protein L21 OS=Homo sapiens OX=9606 GN=RPL21","RPL21",18.565,5.6606,15,4,4,4,0.87,0.815,0.794,1.121,1.239,1.146,1.414,1.06E-3,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0006518 peptide metabolic process; GO:0072594 establishment of protein localization to organelle; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0051649 establishment of localization in cell; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0070972 protein localization to endoplasmic reticulum; GO:0006364 rRNA processing; GO:0006413 translational initiation; GO:1901361 organic cyclic compound catabolic process; GO:0019538 protein metabolic process; GO:0033365 protein localization to organelle; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0006412 translation; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0016072 rRNA metabolic process; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0072657 protein localization to membrane; GO:0043043 peptide biosynthetic process; GO:0042254 ribosome biogenesis; GO:1901360 organic cyclic compound metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032774 RNA biosynthetic process; GO:0045047 protein targeting to ER; GO:0043603 cellular amide metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0006401 RNA catabolic process; GO:0016070 RNA metabolic process; GO:0019439 aromatic compound catabolic process; GO:1901575 organic substance catabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0019083 viral transcription; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0046907 intracellular transport; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0044267 cellular protein metabolic process; GO:0048519 negative regulation of biological process; GO:0006613 cotranslational protein targeting to membrane; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0016032 viral process; GO:0019080 viral gene expression; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0006886 intracellular protein transport; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0009059 macromolecule biosynthetic process; GO:0034613 cellular protein localization; GO:0090150 establishment of protein localization to membrane; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0051179 localization; GO:0009056 catabolic process; GO:0034660 ncRNA metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0005840 ribosome; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0043232 intracellular non-membrane-bounded organelle; GO:0022625 cytosolic large ribosomal subunit; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0015934 large ribosomal subunit; GO:0044391 ribosomal subunit; GO:0005622 intracellular; GO:0044464 cell part; GO:0044445 cytosolic part; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0044444 cytoplasmic part; GO:0022626 cytosolic ribosome; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0005198 structural molecule activity; GO:0003735 structural constituent of ribosome; ","K02889","RP-L21e; large subunit ribosomal protein L21e","hsa03010 Ribosome - Homo sapiens (human); ","IPR008991; ","Translation protein SH3-like domain; \r"]
["P46782","40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5","RPS5",22.876,69.125,27,6,15,6,0.838,0.832,0.831,1.179,1.132,1.072,1.353,0.00834,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0065008 regulation of biological quality; GO:0072594 establishment of protein localization to organelle; GO:0006518 peptide metabolic process; GO:0010608 posttranscriptional regulation of gene expression; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0051649 establishment of localization in cell; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0070972 protein localization to endoplasmic reticulum; GO:0006364 rRNA processing; GO:0006413 translational initiation; GO:1901361 organic cyclic compound catabolic process; GO:0033365 protein localization to organelle; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0006412 translation; GO:0016072 rRNA metabolic process; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0072657 protein localization to membrane; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0043043 peptide biosynthetic process; GO:0042254 ribosome biogenesis; GO:1901360 organic cyclic compound metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032774 RNA biosynthetic process; GO:0045047 protein targeting to ER; GO:0043603 cellular amide metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0016070 RNA metabolic process; GO:0006401 RNA catabolic process; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0019083 viral transcription; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0044267 cellular protein metabolic process; GO:0006613 cotranslational protein targeting to membrane; GO:0048519 negative regulation of biological process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0016032 viral process; GO:0009889 regulation of biosynthetic process; GO:0019080 viral gene expression; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0006886 intracellular protein transport; GO:0051171 regulation of nitrogen compound metabolic process; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0034613 cellular protein localization; GO:0009059 macromolecule biosynthetic process; GO:0090150 establishment of protein localization to membrane; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0006448 regulation of translational elongation; GO:0010629 negative regulation of gene expression; GO:0006450 regulation of translational fidelity; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0034248 regulation of cellular amide metabolic process; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0051246 regulation of protein metabolic process; GO:0006417 regulation of translation; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0051179 localization; GO:0009056 catabolic process; GO:0034660 ncRNA metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:0046700 heterocycle catabolic process; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0030054 cell junction; GO:0031982 vesicle; GO:0015935 small ribosomal subunit; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0005925 focal adhesion; GO:0070013 intracellular organelle lumen; GO:0044391 ribosomal subunit; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0044445 cytosolic part; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0022626 cytosolic ribosome; GO:0043229 intracellular organelle; GO:0005840 ribosome; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0031012 extracellular matrix; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0022627 cytosolic small ribosomal subunit; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003729 mRNA binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0005198 structural molecule activity; GO:0003735 structural constituent of ribosome; ","K02989","RP-S5e; small subunit ribosomal protein S5e","hsa03010 Ribosome - Homo sapiens (human); ","IPR023798; ","Ribosomal protein S7 domain; \r"]
["P46783","40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10","RPS10",18.898,12.509,39.4,7,12,7,0.853,0.811,0.786,1.159,1.24,1.178,1.46,0.000265,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0072594 establishment of protein localization to organelle; GO:0006518 peptide metabolic process; GO:0022618 ribonucleoprotein complex assembly; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0051649 establishment of localization in cell; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0071826 ribonucleoprotein complex subunit organization; GO:0070972 protein localization to endoplasmic reticulum; GO:0022607 cellular component assembly; GO:0006364 rRNA processing; GO:0065003 macromolecular complex assembly; GO:0006413 translational initiation; GO:1901361 organic cyclic compound catabolic process; GO:0033365 protein localization to organelle; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0006412 translation; GO:0016072 rRNA metabolic process; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0072657 protein localization to membrane; GO:0043043 peptide biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0042254 ribosome biogenesis; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032774 RNA biosynthetic process; GO:0045047 protein targeting to ER; GO:0043603 cellular amide metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0016070 RNA metabolic process; GO:0006401 RNA catabolic process; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0019083 viral transcription; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0044267 cellular protein metabolic process; GO:0006613 cotranslational protein targeting to membrane; GO:0048519 negative regulation of biological process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0070925 organelle assembly; GO:0006139 nucleobase-containing compound metabolic process; GO:0016032 viral process; GO:0019080 viral gene expression; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0006886 intracellular protein transport; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0034613 cellular protein localization; GO:0009059 macromolecule biosynthetic process; GO:0090150 establishment of protein localization to membrane; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0034622 cellular macromolecular complex assembly; GO:0044265 cellular macromolecule catabolic process; GO:0042274 ribosomal small subunit biogenesis; GO:0010629 negative regulation of gene expression; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0000028 ribosomal small subunit assembly; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0043933 macromolecular complex subunit organization; GO:0042255 ribosome assembly; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006996 organelle organization; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0051179 localization; GO:0009056 catabolic process; GO:0034660 ncRNA metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0071840 cellular component organization or biogenesis; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0030054 cell junction; GO:0015935 small ribosomal subunit; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005925 focal adhesion; GO:0070013 intracellular organelle lumen; GO:0044391 ribosomal subunit; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0044445 cytosolic part; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0022626 cytosolic ribosome; GO:0043229 intracellular organelle; GO:0005840 ribosome; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0031012 extracellular matrix; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0022627 cytosolic small ribosomal subunit; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0005198 structural molecule activity; GO:0003735 structural constituent of ribosome; ","K02947","RP-S10e; small subunit ribosomal protein S10e","hsa03010 Ribosome - Homo sapiens (human); ","IPR005326; ","\"Plectin/S10, N-terminal; \"\r"]
["P46939","Utrophin OS=Homo sapiens OX=9606 GN=UTRN","UTRN",394.46,208.72,15.5,50,67,48,1.118,1.101,1.085,0.914,0.911,0.909,0.827,2.38e-05,"nucleus\r","GO:0007528 neuromuscular junction development; GO:0044707 single-multicellular organism process; GO:0001952 regulation of cell-matrix adhesion; GO:0016043 cellular component organization; GO:0002028 regulation of sodium ion transport; GO:0003012 muscle system process; GO:0014874 response to stimulus involved in regulation of muscle adaptation; GO:0014894 response to denervation involved in regulation of muscle adaptation; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:0006936 muscle contraction; GO:0032879 regulation of localization; GO:0014870 response to muscle inactivity; GO:0061061 muscle structure development; GO:0010959 regulation of metal ion transport; GO:0044057 regulation of system process; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:1904062 regulation of cation transmembrane transport; GO:0032409 regulation of transporter activity; GO:0032502 developmental process; GO:0001954 positive regulation of cell-matrix adhesion; GO:0003008 system process; GO:0045785 positive regulation of cell adhesion; GO:0048731 system development; GO:0051049 regulation of transport; GO:0043269 regulation of ion transport; GO:0044763 single-organism cellular process; GO:0022898 regulation of transmembrane transporter activity; GO:2000649 regulation of sodium ion transmembrane transporter activity; GO:0090257 regulation of muscle system process; GO:0050808 synapse organization; GO:0032501 multicellular organismal process; GO:0048518 positive regulation of biological process; GO:0030155 regulation of cell adhesion; GO:0010811 positive regulation of cell-substrate adhesion; GO:0034762 regulation of transmembrane transport; GO:0048513 animal organ development; GO:0014854 response to inactivity; GO:0043502 regulation of muscle adaptation; GO:0050789 regulation of biological process; GO:0034765 regulation of ion transmembrane transport; GO:0007517 muscle organ development; GO:0044767 single-organism developmental process; GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation; GO:0048583 regulation of response to stimulus; GO:0065009 regulation of molecular function; GO:1902305 regulation of sodium ion transmembrane transport; GO:0032412 regulation of ion transmembrane transporter activity; GO:0010810 regulation of cell-substrate adhesion; GO:0048856 anatomical structure development; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0099568 cytoplasmic region; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0098858 actin-based cell projection; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0098590 plasma membrane region; GO:0005622 intracellular; GO:0097060 synaptic membrane; GO:0030175 filopodium; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043233 organelle lumen; GO:0042995 cell projection; GO:0044430 cytoskeletal part; GO:0098797 plasma membrane protein complex; GO:0031981 nuclear lumen; GO:0030427 site of polarized growth; GO:0005576 extracellular region; GO:0031527 filopodium membrane; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0098794 postsynapse; GO:0043234 protein complex; GO:0042383 sarcolemma; GO:0043230 extracellular organelle; GO:0005938 cell cortex; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0030863 cortical cytoskeleton; GO:0044424 intracellular part; GO:0030864 cortical actin cytoskeleton; GO:0030426 growth cone; GO:0005856 cytoskeleton; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0044425 membrane part; GO:1903561 extracellular vesicle; GO:0044456 synapse part; GO:0043229 intracellular organelle; GO:0090665 glycoprotein complex; GO:0043232 intracellular non-membrane-bounded organelle; GO:0031594 neuromuscular junction; GO:0044446 intracellular organelle part; GO:0044463 cell projection part; GO:0015629 actin cytoskeleton; GO:0045202 synapse; GO:0016010 dystrophin-associated glycoprotein complex; GO:0045211 postsynaptic membrane; GO:0043226 organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0044448 cell cortex part; GO:0031253 cell projection membrane; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0051015 actin filament binding; GO:0005102 receptor binding; GO:0043167 ion binding; GO:0019901 protein kinase binding; GO:0044877 macromolecular complex binding; GO:0005178 integrin binding; GO:0005515 protein binding; GO:0008270 zinc ion binding; GO:0019900 kinase binding; GO:0050839 cell adhesion molecule binding; GO:0008092 cytoskeletal protein binding; GO:0046914 transition metal ion binding; GO:0017166 vinculin binding; GO:0005488 binding; GO:0003779 actin binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0019899 enzyme binding; GO:0032403 protein complex binding; ",{"$nulls":3},"IPR015154; IPR001202; IPR011992; IPR001715; IPR015153; IPR000433; ","\"EF-hand domain, type 2; WW domain; EF-hand domain pair; Calponin homology domain; EF-hand domain, type 1; Zinc finger, ZZ-type; \"\r"]
["P46940","Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1","IQGAP1",189.25,323.31,40.4,58,124,56,1,0.986,0.972,1.009,1.004,1.016,1.024,0.0556,"cytoplasm\r","GO:0044700 single organism signaling; GO:0030335 positive regulation of cell migration; GO:0048008 platelet-derived growth factor receptor signaling pathway; GO:0045321 leukocyte activation; GO:0032270 positive regulation of cellular protein metabolic process; GO:0007166 cell surface receptor signaling pathway; GO:0032989 cellular component morphogenesis; GO:0036119 response to platelet-derived growth factor; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0051894 positive regulation of focal adhesion assembly; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0038127 ERBB signaling pathway; GO:0009719 response to endogenous stimulus; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0070848 response to growth factor; GO:0051347 positive regulation of transferase activity; GO:1901652 response to peptide; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0007399 nervous system development; GO:0042325 regulation of phosphorylation; GO:0035305 negative regulation of dephosphorylation; GO:0051716 cellular response to stimulus; GO:0001954 positive regulation of cell-matrix adhesion; GO:0002443 leukocyte mediated immunity; GO:0051174 regulation of phosphorus metabolic process; GO:0002064 epithelial cell development; GO:0080090 regulation of primary metabolic process; GO:0031346 positive regulation of cell projection organization; GO:0048699 generation of neurons; GO:0016049 cell growth; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0048812 neuron projection morphogenesis; GO:0051272 positive regulation of cellular component movement; GO:0031323 regulation of cellular metabolic process; GO:0043086 negative regulation of catalytic activity; GO:1901888 regulation of cell junction assembly; GO:0032501 multicellular organismal process; GO:0010811 positive regulation of cell-substrate adhesion; GO:0006810 transport; GO:0000902 cell morphogenesis; GO:0010243 response to organonitrogen compound; GO:0048513 animal organ development; GO:0051336 regulation of hydrolase activity; GO:0071364 cellular response to epidermal growth factor stimulus; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0010604 positive regulation of macromolecule metabolic process; GO:1904752 regulation of vascular associated smooth muscle cell migration; GO:0051094 positive regulation of developmental process; GO:0010975 regulation of neuron projection development; GO:0030855 epithelial cell differentiation; GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation; GO:0050794 regulation of cellular process; GO:0001952 regulation of cell-matrix adhesion; GO:0044707 single-multicellular organism process; GO:0002283 neutrophil activation involved in immune response; GO:0031399 regulation of protein modification process; GO:1901700 response to oxygen-containing compound; GO:1990138 neuron projection extension; GO:0071902 positive regulation of protein serine/threonine kinase activity; GO:2000147 positive regulation of cell motility; GO:0007173 epidermal growth factor receptor signaling pathway; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0051239 regulation of multicellular organismal process; GO:0045597 positive regulation of cell differentiation; GO:0060341 regulation of cellular localization; GO:1900006 positive regulation of dendrite development; GO:0009653 anatomical structure morphogenesis; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0051345 positive regulation of hydrolase activity; GO:2000145 regulation of cell motility; GO:0051338 regulation of transferase activity; GO:0071774 response to fibroblast growth factor; GO:0032880 regulation of protein localization; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:1900086 positive regulation of peptidyl-tyrosine autophosphorylation; GO:0072009 nephron epithelium development; GO:0001822 kidney development; GO:1902531 regulation of intracellular signal transduction; GO:0045785 positive regulation of cell adhesion; GO:0043547 positive regulation of GTPase activity; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0060560 developmental growth involved in morphogenesis; GO:0002376 immune system process; GO:0030334 regulation of cell migration; GO:1900084 regulation of peptidyl-tyrosine autophosphorylation; GO:0010033 response to organic substance; GO:0002263 cell activation involved in immune response; GO:0009892 negative regulation of metabolic process; GO:0030155 regulation of cell adhesion; GO:0014911 positive regulation of smooth muscle cell migration; GO:0030182 neuron differentiation; GO:0045055 regulated exocytosis; GO:0043406 positive regulation of MAP kinase activity; GO:0051247 positive regulation of protein metabolic process; GO:0010976 positive regulation of neuron projection development; GO:0031325 positive regulation of cellular metabolic process; GO:0001775 cell activation; GO:0050769 positive regulation of neurogenesis; GO:0072073 kidney epithelium development; GO:0035850 epithelial cell differentiation involved in kidney development; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0006955 immune response; GO:0071248 cellular response to metal ion; GO:0048589 developmental growth; GO:0010810 regulation of cell-substrate adhesion; GO:0050793 regulation of developmental process; GO:0040007 growth; GO:1903827 regulation of cellular protein localization; GO:0045936 negative regulation of phosphate metabolic process; GO:0006887 exocytosis; GO:0045666 positive regulation of neuron differentiation; GO:1903391 regulation of adherens junction organization; GO:0031954 positive regulation of protein autophosphorylation; GO:0040017 positive regulation of locomotion; GO:0023051 regulation of signaling; GO:0048869 cellular developmental process; GO:0048666 neuron development; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0090109 regulation of cell-substrate junction assembly; GO:0022008 neurogenesis; GO:0071363 cellular response to growth factor stimulus; GO:0008543 fibroblast growth factor receptor signaling pathway; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0032990 cell part morphogenesis; GO:0035303 regulation of dephosphorylation; GO:0048858 cell projection morphogenesis; GO:0010035 response to inorganic substance; GO:0072015 glomerular visceral epithelial cell development; GO:0033674 positive regulation of kinase activity; GO:0010720 positive regulation of cell development; GO:0061318 renal filtration cell differentiation; GO:0034260 negative regulation of GTPase activity; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0070887 cellular response to chemical stimulus; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0045937 positive regulation of phosphate metabolic process; GO:0009888 tissue development; GO:0002446 neutrophil mediated immunity; GO:0051962 positive regulation of nervous system development; GO:0048522 positive regulation of cellular process; GO:1901890 positive regulation of cell junction assembly; GO:0023052 signaling; GO:0036120 cellular response to platelet-derived growth factor stimulus; GO:0002444 myeloid leukocyte mediated immunity; GO:0010038 response to metal ion; GO:0072310 glomerular epithelial cell development; GO:1903393 positive regulation of adherens junction organization; GO:0001655 urogenital system development; GO:0032268 regulation of cellular protein metabolic process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0043434 response to peptide hormone; GO:0045664 regulation of neuron differentiation; GO:0030030 cell projection organization; GO:0032940 secretion by cell; GO:0072010 glomerular epithelium development; GO:0071241 cellular response to inorganic substance; GO:0065009 regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0043299 leukocyte degranulation; GO:0019220 regulation of phosphate metabolic process; GO:0072112 glomerular visceral epithelial cell differentiation; GO:0048856 anatomical structure development; GO:0043549 regulation of kinase activity; GO:2000026 regulation of multicellular organismal development; GO:0045859 regulation of protein kinase activity; GO:0016043 cellular component organization; GO:0002252 immune effector process; GO:0050730 regulation of peptidyl-tyrosine phosphorylation; GO:0043405 regulation of MAP kinase activity; GO:0060255 regulation of macromolecule metabolic process; GO:1903829 positive regulation of cellular protein localization; GO:0071310 cellular response to organic substance; GO:0051893 regulation of focal adhesion assembly; GO:0031344 regulation of cell projection organization; GO:0072001 renal system development; GO:0044087 regulation of cellular component biogenesis; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0051346 negative regulation of hydrolase activity; GO:1904754 positive regulation of vascular associated smooth muscle cell migration; GO:0032835 glomerulus development; GO:0030154 cell differentiation; GO:0043408 regulation of MAPK cascade; GO:0023056 positive regulation of signaling; GO:0051592 response to calcium ion; GO:0072006 nephron development; GO:0010647 positive regulation of cell communication; GO:0036230 granulocyte activation; GO:0072311 glomerular epithelial cell differentiation; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0070849 response to epidermal growth factor; GO:0001932 regulation of protein phosphorylation; GO:0071277 cellular response to calcium ion; GO:0031401 positive regulation of protein modification process; GO:1990776 response to angiotensin; GO:0031952 regulation of protein autophosphorylation; GO:0045860 positive regulation of protein kinase activity; GO:0043312 neutrophil degranulation; GO:0001934 positive regulation of protein phosphorylation; GO:0031175 neuron projection development; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0002366 leukocyte activation involved in immune response; GO:0061005 cell differentiation involved in kidney development; GO:0042119 neutrophil activation; GO:0051246 regulation of protein metabolic process; GO:0071495 cellular response to endogenous stimulus; GO:0044767 single-organism developmental process; GO:0048588 developmental cell growth; GO:0044344 cellular response to fibroblast growth factor stimulus; GO:0010563 negative regulation of phosphorus metabolic process; GO:0001817 regulation of cytokine production; GO:0050773 regulation of dendrite development; GO:0009967 positive regulation of signal transduction; GO:0051128 regulation of cellular component organization; GO:0043410 positive regulation of MAPK cascade; GO:0009725 response to hormone; GO:0040012 regulation of locomotion; GO:0044089 positive regulation of cellular component biogenesis; GO:0050767 regulation of neurogenesis; GO:0014910 regulation of smooth muscle cell migration; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0019898 extrinsic component of membrane; GO:0031090 organelle membrane; GO:0098857 membrane microdomain; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0009898 cytoplasmic side of plasma membrane; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0098589 membrane region; GO:0043005 neuron projection; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0005924 cell-substrate adherens junction; GO:0098552 side of membrane; GO:0031252 cell leading edge; GO:0099513 polymeric cytoskeletal fiber; GO:0042995 cell projection; GO:0044430 cytoskeletal part; GO:0019897 extrinsic component of plasma membrane; GO:0070161 anchoring junction; GO:0030496 midbody; GO:0012506 vesicle membrane; GO:0030427 site of polarized growth; GO:0005576 extracellular region; GO:0016328 lateral plasma membrane; GO:0099081 supramolecular polymer; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0030424 axon; GO:0030667 secretory granule membrane; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0005874 microtubule; GO:0031410 cytoplasmic vesicle; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0036057 slit diaphragm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0099512 supramolecular fiber; GO:0030426 growth cone; GO:0031234 extrinsic component of cytoplasmic side of plasma membrane; GO:0005911 cell-cell junction; GO:0098562 cytoplasmic side of membrane; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0005856 cytoskeleton; GO:0015630 microtubule cytoskeleton; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0005912 adherens junction; GO:0005884 actin filament; GO:0030141 secretory granule; GO:0045121 membrane raft; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0015629 actin cytoskeleton; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0035770 ribonucleoprotein granule; GO:0036056 filtration diaphragm; GO:0001726 ruffle; GO:0044444 cytoplasmic part; ","GO:0048365 Rac GTPase binding; GO:0019903 protein phosphatase binding; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0019901 protein kinase binding; GO:0030695 GTPase regulator activity; GO:0005515 protein binding; GO:0019207 kinase regulator activity; GO:0005095 GTPase inhibitor activity; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0019209 kinase activator activity; GO:0017016 Ras GTPase binding; GO:0005488 binding; GO:0035091 phosphatidylinositol binding; GO:0045296 cadherin binding; GO:0008289 lipid binding; GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding; GO:0043169 cation binding; GO:0044548 S100 protein binding; GO:0043168 anion binding; GO:0019902 phosphatase binding; GO:0051020 GTPase binding; GO:0008047 enzyme activator activity; GO:0031267 small GTPase binding; GO:0017048 Rho GTPase binding; GO:1901981 phosphatidylinositol phosphate binding; GO:0043539 protein serine/threonine kinase activator activity; GO:0030295 protein kinase activator activity; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0051019 mitogen-activated protein kinase binding; GO:0019887 protein kinase regulator activity; GO:0019900 kinase binding; GO:0005516 calmodulin binding; GO:0050839 cell adhesion molecule binding; GO:0030234 enzyme regulator activity; GO:0005543 phospholipid binding; GO:0046872 metal ion binding; GO:0019904 protein domain specific binding; GO:0005509 calcium ion binding; GO:0019899 enzyme binding; GO:0032403 protein complex binding; GO:0005096 GTPase activator activity; ","K16848","IQGAP1; Ras GTPase-activating-like protein IQGAP1","hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa04520 Adherens junction - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); ","IPR001936; IPR001202; IPR001715; IPR027417; IPR027401; IPR000593; IPR008936; ","\"Ras GTPase-activating protein; WW domain; Calponin homology domain; P-loop containing nucleoside triphosphate hydrolase; Myosin-like IQ motif-containing domain; RasGAP protein, C-terminal; Rho GTPase activation protein; \"\r"]
["P47712","Cytosolic phospholipase A2 OS=Homo sapiens OX=9606 GN=PLA2G4A","PLA2G4A",85.238,3.2946,1.9,1,1,1,1.119,0.931,1.074,0.969,1.02,0.898,0.924,0.313,"nucleus\r","GO:0046470 phosphatidylcholine metabolic process; GO:0046717 acid secretion; GO:0046486 glycerolipid metabolic process; GO:0016053 organic acid biosynthetic process; GO:0006654 phosphatidic acid biosynthetic process; GO:0008654 phospholipid biosynthetic process; GO:1901568 fatty acid derivative metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0008610 lipid biosynthetic process; GO:0009395 phospholipid catabolic process; GO:0046456 icosanoid biosynthetic process; GO:0008152 metabolic process; GO:0006663 platelet activating factor biosynthetic process; GO:0015718 monocarboxylic acid transport; GO:0006650 glycerophospholipid metabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0046488 phosphatidylinositol metabolic process; GO:0033036 macromolecule localization; GO:0070887 cellular response to chemical stimulus; GO:0006690 icosanoid metabolic process; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0006629 lipid metabolic process; GO:0051716 cellular response to stimulus; GO:0006869 lipid transport; GO:0044281 small molecule metabolic process; GO:0036152 phosphatidylethanolamine acyl-chain remodeling; GO:0044763 single-organism cellular process; GO:0046473 phosphatidic acid metabolic process; GO:0046942 carboxylic acid transport; GO:0006810 transport; GO:0090407 organophosphate biosynthetic process; GO:0006658 phosphatidylserine metabolic process; GO:1901575 organic substance catabolic process; GO:0046394 carboxylic acid biosynthetic process; GO:0071715 icosanoid transport; GO:1901571 fatty acid derivative transport; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0044710 single-organism metabolic process; GO:0035965 cardiolipin acyl-chain remodeling; GO:0046474 glycerophospholipid biosynthetic process; GO:0006082 organic acid metabolic process; GO:0043436 oxoacid metabolic process; GO:0033559 unsaturated fatty acid metabolic process; GO:0050794 regulation of cellular process; GO:0019369 arachidonic acid metabolic process; GO:0042127 regulation of cell proliferation; GO:0046434 organophosphate catabolic process; GO:0046677 response to antibiotic; GO:0097164 ammonium ion metabolic process; GO:0050482 arachidonic acid secretion; GO:0050896 response to stimulus; GO:1901566 organonitrogen compound biosynthetic process; GO:0036151 phosphatidylcholine acyl-chain remodeling; GO:0071704 organic substance metabolic process; GO:0032309 icosanoid secretion; GO:0046471 phosphatidylglycerol metabolic process; GO:0036150 phosphatidylserine acyl-chain remodeling; GO:0015908 fatty acid transport; GO:0006575 cellular modified amino acid metabolic process; GO:1902578 single-organism localization; GO:0044248 cellular catabolic process; GO:0009987 cellular process; GO:0016042 lipid catabolic process; GO:0044711 single-organism biosynthetic process; GO:0032048 cardiolipin metabolic process; GO:0044712 single-organism catabolic process; GO:1901570 fatty acid derivative biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0010876 lipid localization; GO:0071702 organic substance transport; GO:0006631 fatty acid metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0015849 organic acid transport; GO:0044249 cellular biosynthetic process; GO:0045017 glycerolipid biosynthetic process; GO:1903963 arachidonate transport; GO:0015909 long-chain fatty acid transport; GO:0006820 anion transport; GO:0015711 organic anion transport; GO:0071236 cellular response to antibiotic; GO:0036149 phosphatidylinositol acyl-chain remodeling; GO:0006793 phosphorus metabolic process; GO:0001676 long-chain fatty acid metabolic process; GO:0006811 ion transport; GO:0044283 small molecule biosynthetic process; GO:0019752 carboxylic acid metabolic process; GO:0044242 cellular lipid catabolic process; GO:0019637 organophosphate metabolic process; GO:0006644 phospholipid metabolic process; GO:0051179 localization; GO:0009056 catabolic process; GO:0036148 phosphatidylglycerol acyl-chain remodeling; GO:0046469 platelet activating factor metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005740 mitochondrial envelope; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0019866 organelle inner membrane; GO:0005811 lipid particle; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0005789 endoplasmic reticulum membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0044429 mitochondrial part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044432 endoplasmic reticulum part; GO:0031975 envelope; GO:0005794 Golgi apparatus; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0005544 calcium-dependent phospholipid binding; GO:0052689 carboxylic ester hydrolase activity; GO:0043167 ion binding; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0016298 lipase activity; GO:0047498 calcium-dependent phospholipase A2 activity; GO:0008970 phosphatidylcholine 1-acylhydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0005543 phospholipid binding; GO:0004623 phospholipase A2 activity; GO:0016788 hydrolase activity, acting on ester bonds; GO:0004620 phospholipase activity; GO:0004622 lysophospholipase activity; GO:0008289 lipid binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0005509 calcium ion binding; ","K16342","PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]","hsa04921 Oxytocin signaling pathway - Homo sapiens (human); hsa05231 Choline metabolism in cancer - Homo sapiens (human); hsa04072 Phospholipase D signaling pathway - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa04370 VEGF signaling pathway - Homo sapiens (human); hsa04014 Ras signaling pathway - Homo sapiens (human); hsa00590 Arachidonic acid metabolism - Homo sapiens (human); hsa04217 Necroptosis - Homo sapiens (human); hsa04270 Vascular smooth muscle contraction - Homo sapiens (human); hsa04010 MAPK signaling pathway - Homo sapiens (human); hsa04750 Inflammatory mediator regulation of TRP channels - Homo sapiens (human); hsa04726 Serotonergic synapse - Homo sapiens (human); hsa04724 Glutamatergic synapse - Homo sapiens (human); hsa00565 Ether lipid metabolism - Homo sapiens (human); hsa04666 Fc gamma R-mediated phagocytosis - Homo sapiens (human); hsa00591 Linoleic acid metabolism - Homo sapiens (human); hsa04664 Fc epsilon RI signaling pathway - Homo sapiens (human); hsa04913 Ovarian steroidogenesis - Homo sapiens (human); hsa04912 GnRH signaling pathway - Homo sapiens (human); hsa00592 alpha-Linolenic acid metabolism - Homo sapiens (human); hsa04730 Long-term depression - Homo sapiens (human); hsa04611 Platelet activation - Homo sapiens (human); hsa00564 Glycerophospholipid metabolism - Homo sapiens (human); ","IPR016035; IPR002642; IPR000008; ","\"Acyl transferase/acyl hydrolase/lysophospholipase; Lysophospholipase, catalytic domain; C2 domain; \"\r"]
["P47755","F-actin-capping protein subunit alpha-2 OS=Homo sapiens OX=9606 GN=CAPZA2","CAPZA2",32.949,130.17,32.9,7,13,6,0.971,1.053,1.054,0.963,0.958,0.982,0.943,0.11,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0050794 regulation of cellular process; GO:0030833 regulation of actin filament polymerization; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0030835 negative regulation of actin filament depolymerization; GO:0032956 regulation of actin cytoskeleton organization; GO:0051129 negative regulation of cellular component organization; GO:0044699 single-organism process; GO:0044087 regulation of cellular component biogenesis; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:0030832 regulation of actin filament length; GO:0045087 innate immune response; GO:0007599 hemostasis; GO:0009611 response to wounding; GO:1901880 negative regulation of protein depolymerization; GO:0051693 actin filament capping; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0032535 regulation of cellular component size; GO:0032271 regulation of protein polymerization; GO:0051493 regulation of cytoskeleton organization; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0031333 negative regulation of protein complex assembly; GO:0071822 protein complex subunit organization; GO:0050878 regulation of body fluid levels; GO:0006950 response to stress; GO:1901879 regulation of protein depolymerization; GO:0051494 negative regulation of cytoskeleton organization; GO:0044763 single-organism cellular process; GO:0033043 regulation of organelle organization; GO:0002376 immune system process; GO:0032970 regulation of actin filament-based process; GO:0032501 multicellular organismal process; GO:0043933 macromolecular complex subunit organization; GO:0008064 regulation of actin polymerization or depolymerization; GO:0010639 negative regulation of organelle organization; GO:0043254 regulation of protein complex assembly; GO:0050789 regulation of biological process; GO:0051016 barbed-end actin filament capping; GO:0042060 wound healing; GO:0043242 negative regulation of protein complex disassembly; GO:1902904 negative regulation of supramolecular fiber organization; GO:0006928 movement of cell or subcellular component; GO:0090066 regulation of anatomical structure size; GO:0030837 negative regulation of actin filament polymerization; GO:0006952 defense response; GO:0050817 coagulation; GO:0043244 regulation of protein complex disassembly; GO:0030834 regulation of actin filament depolymerization; GO:0051128 regulation of cellular component organization; GO:0070271 protein complex biogenesis; GO:0006955 immune response; GO:0032272 negative regulation of protein polymerization; GO:1902903 regulation of supramolecular fiber organization; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0098862 cluster of actin-based cell projections; GO:0044421 extracellular region part; GO:0005938 cell cortex; GO:0005903 brush border; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0099568 cytoplasmic region; GO:0031982 vesicle; GO:0030863 cortical cytoskeleton; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0008290 F-actin capping protein complex; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0015629 actin cytoskeleton; GO:0043226 organelle; GO:0044448 cell cortex part; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0003779 actin binding; GO:0005515 protein binding; GO:0008092 cytoskeletal protein binding; GO:0005488 binding; ","K10364","CAPZA; capping protein (actin filament) muscle Z-line, alpha","hsa04144 Endocytosis - Homo sapiens (human); "]
["P47914","60S ribosomal protein L29 OS=Homo sapiens OX=9606 GN=RPL29","RPL29",17.752,6.238,9.4,1,1,1,0.949,0.931,0.955,1.113,0.973,1.082,1.117,0.0582,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0072594 establishment of protein localization to organelle; GO:0006518 peptide metabolic process; GO:0022414 reproductive process; GO:0007566 embryo implantation; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0051649 establishment of localization in cell; GO:0002181 cytoplasmic translation; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0070972 protein localization to endoplasmic reticulum; GO:0006364 rRNA processing; GO:0044702 single organism reproductive process; GO:0044706 multi-multicellular organism process; GO:0006413 translational initiation; GO:1901361 organic cyclic compound catabolic process; GO:0033365 protein localization to organelle; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0006412 translation; GO:0016072 rRNA metabolic process; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0072657 protein localization to membrane; GO:0043043 peptide biosynthetic process; GO:0042254 ribosome biogenesis; GO:1901360 organic cyclic compound metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032774 RNA biosynthetic process; GO:0045047 protein targeting to ER; GO:0043603 cellular amide metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0016070 RNA metabolic process; GO:0006401 RNA catabolic process; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0019083 viral transcription; GO:0016071 mRNA metabolic process; GO:0048856 anatomical structure development; GO:1901362 organic cyclic compound biosynthetic process; GO:0000003 reproduction; GO:0046907 intracellular transport; GO:0044707 single-multicellular organism process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0044267 cellular protein metabolic process; GO:0006613 cotranslational protein targeting to membrane; GO:0048519 negative regulation of biological process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0007565 female pregnancy; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0016032 viral process; GO:0019080 viral gene expression; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0006886 intracellular protein transport; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0034655 nucleobase-containing compound catabolic process; GO:0034613 cellular protein localization; GO:0009059 macromolecule biosynthetic process; GO:0090150 establishment of protein localization to membrane; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0044767 single-organism developmental process; GO:0044703 multi-organism reproductive process; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0051179 localization; GO:0034660 ncRNA metabolic process; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; GO:1901564 organonitrogen compound metabolic process; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; ","GO:0005840 ribosome; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0043232 intracellular non-membrane-bounded organelle; GO:0022625 cytosolic large ribosomal subunit; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0015934 large ribosomal subunit; GO:0044391 ribosomal subunit; GO:0005622 intracellular; GO:0044464 cell part; GO:0044445 cytosolic part; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0044444 cytoplasmic part; GO:0022626 cytosolic ribosome; ","GO:0003723 RNA binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0008201 heparin binding; GO:0003735 structural constituent of ribosome; GO:1901681 sulfur compound binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0050839 cell adhesion molecule binding; GO:0097367 carbohydrate derivative binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0003676 nucleic acid binding; GO:0043168 anion binding; GO:0005539 glycosaminoglycan binding; GO:0005198 structural molecule activity; ","K02905","RP-L29e; large subunit ribosomal protein L29e","hsa03010 Ribosome - Homo sapiens (human); "]
["P47929","Galectin-7 OS=Homo sapiens OX=9606 GN=LGALS7","LGALS7",15.075,155.63,77.9,9,47,9,0.976,0.953,0.939,0.964,1.051,1.052,1.069,0.0995,"mitochondria\r","GO:0022610 biological adhesion; GO:0008219 cell death; GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; GO:0006915 apoptotic process; GO:0098609 cell-cell adhesion; GO:0044763 single-organism cellular process; GO:0007155 cell adhesion; GO:0044699 single-organism process; GO:0012501 programmed cell death; GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules; GO:0009987 cellular process; ","GO:0043229 intracellular organelle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0030246 carbohydrate binding; GO:0005488 binding; ","K10092",null,null,"IPR001079; IPR013320; ","\"Galectin, carbohydrate recognition domain; Concanavalin A-like lectin/glucanase domain; \"\r"]
["P48059","LIM and senescent cell antigen-like-containing domain protein 1 OS=Homo sapiens OX=9606 GN=LIMS1","LIMS1",37.251,43.962,37.8,10,16,6,1.035,1.024,1.035,0.98,0.967,1.027,0.961,0.0986,"nucleus\r","GO:0044085 cellular component biogenesis; GO:1903391 regulation of adherens junction organization; GO:0048869 cellular developmental process; GO:0071560 cellular response to transforming growth factor beta stimulus; GO:0090109 regulation of cell-substrate junction assembly; GO:0044699 single-organism process; GO:0071363 cellular response to growth factor stimulus; GO:0051253 negative regulation of RNA metabolic process; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:2001141 regulation of RNA biosynthetic process; GO:0051894 positive regulation of focal adhesion assembly; GO:0009893 positive regulation of metabolic process; GO:0022607 cellular component assembly; GO:0044093 positive regulation of molecular function; GO:0009719 response to endogenous stimulus; GO:0070848 response to growth factor; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0010720 positive regulation of cell development; GO:0070887 cellular response to chemical stimulus; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0032502 developmental process; GO:0001954 positive regulation of cell-matrix adhesion; GO:0010468 regulation of gene expression; GO:0051716 cellular response to stimulus; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:1900026 positive regulation of substrate adhesion-dependent cell spreading; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:1901890 positive regulation of cell junction assembly; GO:1901888 regulation of cell junction assembly; GO:0031323 regulation of cellular metabolic process; GO:0071559 response to transforming growth factor beta; GO:0010605 negative regulation of macromolecule metabolic process; GO:0010811 positive regulation of cell-substrate adhesion; GO:1903506 regulation of nucleic acid-templated transcription; GO:1903393 positive regulation of adherens junction organization; GO:0007569 cell aging; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0007568 aging; GO:1902679 negative regulation of RNA biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0051094 positive regulation of developmental process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0001952 regulation of cell-matrix adhesion; GO:0016043 cellular component organization; GO:0034329 cell junction assembly; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0051893 regulation of focal adhesion assembly; GO:0010770 positive regulation of cell morphogenesis involved in differentiation; GO:0044087 regulation of cellular component biogenesis; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0045597 positive regulation of cell differentiation; GO:0045892 negative regulation of transcription, DNA-templated; GO:0051345 positive regulation of hydrolase activity; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:1900024 regulation of substrate adhesion-dependent cell spreading; GO:0051171 regulation of nitrogen compound metabolic process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0006355 regulation of transcription, DNA-templated; GO:0045785 positive regulation of cell adhesion; GO:0010629 negative regulation of gene expression; GO:0043547 positive regulation of GTPase activity; GO:0060284 regulation of cell development; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0010033 response to organic substance; GO:0009892 negative regulation of metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0030155 regulation of cell adhesion; GO:0043085 positive regulation of catalytic activity; GO:0045184 establishment of protein localization; GO:0009890 negative regulation of biosynthetic process; GO:0034330 cell junction organization; GO:0044767 single-organism developmental process; GO:0071495 cellular response to endogenous stimulus; GO:0022603 regulation of anatomical structure morphogenesis; GO:0031327 negative regulation of cellular biosynthetic process; GO:0051128 regulation of cellular component organization; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:0010810 regulation of cell-substrate adhesion; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0022604 regulation of cell morphogenesis; GO:0044089 positive regulation of cellular component biogenesis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0070161 anchoring junction; GO:0044424 intracellular part; GO:0005911 cell-cell junction; GO:0005829 cytosol; GO:0005623 cell; GO:0005886 plasma membrane; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:0048471 perinuclear region of cytoplasm; GO:0030055 cell-substrate junction; GO:0044444 cytoplasmic part; GO:0005924 cell-substrate adherens junction; ","GO:0046914 transition metal ion binding; GO:0005488 binding; GO:0043167 ion binding; GO:0019901 protein kinase binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0008270 zinc ion binding; GO:0019900 kinase binding; GO:0019899 enzyme binding; ",{"$nulls":3},"IPR001781; ","\"Zinc finger, LIM-type; \"\r"]
["P48061","Stromal cell-derived factor 1 OS=Homo sapiens OX=9606 GN=CXCL12","CXCL12",10.666,2.6629,8.6,1,1,1,1.28,0.906,1.239,0.847,1.044,0.705,0.758,0.153,"extracellular\r","GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0009607 response to biotic stimulus; GO:0045927 positive regulation of growth; GO:0001558 regulation of cell growth; GO:0032535 regulation of cellular component size; GO:0055065 metal ion homeostasis; GO:0051493 regulation of cytoskeleton organization; GO:0051716 cellular response to stimulus; GO:0030307 positive regulation of cell growth; GO:1903038 negative regulation of leukocyte cell-cell adhesion; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0048870 cell motility; GO:0006935 chemotaxis; GO:0051704 multi-organism process; GO:0006874 cellular calcium ion homeostasis; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0010243 response to organonitrogen compound; GO:1902532 negative regulation of intracellular signal transduction; GO:0080135 regulation of cellular response to stress; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0060548 negative regulation of cell death; GO:0071675 regulation of mononuclear cell migration; GO:0002687 positive regulation of leukocyte migration; GO:0010975 regulation of neuron projection development; GO:0044707 single-multicellular organism process; GO:0050930 induction of positive chemotaxis; GO:1901700 response to oxygen-containing compound; GO:0022408 negative regulation of cell-cell adhesion; GO:0050926 regulation of positive chemotaxis; GO:0048519 negative regulation of biological process; GO:0009653 anatomical structure morphogenesis; GO:0023057 negative regulation of signaling; GO:1990478 response to ultrasound; GO:0010648 negative regulation of cell communication; GO:0050772 positive regulation of axonogenesis; GO:2000145 regulation of cell motility; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:0070482 response to oxygen levels; GO:2000403 positive regulation of lymphocyte migration; GO:0010959 regulation of metal ion transport; GO:0001936 regulation of endothelial cell proliferation; GO:0030534 adult behavior; GO:0048878 chemical homeostasis; GO:0051928 positive regulation of calcium ion transport; GO:0045785 positive regulation of cell adhesion; GO:0006950 response to stress; GO:0051270 regulation of cellular component movement; GO:0051960 regulation of nervous system development; GO:0060284 regulation of cell development; GO:0051924 regulation of calcium ion transport; GO:0002376 immune system process; GO:0032970 regulation of actin filament-based process; GO:0032101 regulation of response to external stimulus; GO:0010033 response to organic substance; GO:0007186 G-protein coupled receptor signaling pathway; GO:0030336 negative regulation of cell migration; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:0006955 immune response; GO:2000107 negative regulation of leukocyte apoptotic process; GO:0008284 positive regulation of cell proliferation; GO:0031100 animal organ regeneration; GO:0009968 negative regulation of signal transduction; GO:0051674 localization of cell; GO:0040017 positive regulation of locomotion; GO:0023051 regulation of signaling; GO:0048869 cellular developmental process; GO:0048666 neuron development; GO:0051046 regulation of secretion; GO:0044699 single-organism process; GO:0048842 positive regulation of axon extension involved in axon guidance; GO:0040013 negative regulation of locomotion; GO:0007165 signal transduction; GO:0090026 positive regulation of monocyte chemotaxis; GO:0032990 cell part morphogenesis; GO:0033605 positive regulation of catecholamine secretion; GO:0048858 cell projection morphogenesis; GO:0001764 neuron migration; GO:0033603 positive regulation of dopamine secretion; GO:1904995 negative regulation of leukocyte adhesion to vascular endothelial cell; GO:0034097 response to cytokine; GO:0098771 inorganic ion homeostasis; GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage; GO:0090280 positive regulation of calcium ion import; GO:1903530 regulation of secretion by cell; GO:0023052 signaling; GO:0051954 positive regulation of amine transport; GO:0045664 regulation of neuron differentiation; GO:0006952 defense response; GO:0009615 response to virus; GO:0002686 negative regulation of leukocyte migration; GO:0016477 cell migration; GO:0016043 cellular component organization; GO:0043069 negative regulation of programmed cell death; GO:0040008 regulation of growth; GO:0071310 cellular response to organic substance; GO:0010770 positive regulation of cell morphogenesis involved in differentiation; GO:0048638 regulation of developmental growth; GO:0051707 response to other organism; GO:0000904 cell morphogenesis involved in differentiation; GO:0042592 homeostatic process; GO:0009612 response to mechanical stimulus; GO:0030154 cell differentiation; GO:0008361 regulation of cell size; GO:0002690 positive regulation of leukocyte chemotaxis; GO:0055080 cation homeostasis; GO:0043066 negative regulation of apoptotic process; GO:0016032 viral process; GO:0001666 response to hypoxia; GO:0008015 blood circulation; GO:0019221 cytokine-mediated signaling pathway; GO:0045595 regulation of cell differentiation; GO:1903236 regulation of leukocyte tethering or rolling; GO:0051049 regulation of transport; GO:0090279 regulation of calcium ion import; GO:0033043 regulation of organelle organization; GO:0050920 regulation of chemotaxis; GO:0022407 regulation of cell-cell adhesion; GO:2000106 regulation of leukocyte apoptotic process; GO:2000401 regulation of lymphocyte migration; GO:0002684 positive regulation of immune system process; GO:0007626 locomotory behavior; GO:0031099 regeneration; GO:0042981 regulation of apoptotic process; GO:0050767 regulation of neurogenesis; GO:0071840 cellular component organization or biogenesis; GO:0030335 positive regulation of cell migration; GO:0065008 regulation of biological quality; GO:0007166 cell surface receptor signaling pathway; GO:0014059 regulation of dopamine secretion; GO:0007420 brain development; GO:0032989 cellular component morphogenesis; GO:0030832 regulation of actin filament length; GO:0071345 cellular response to cytokine stimulus; GO:0021537 telencephalon development; GO:0007610 behavior; GO:0009605 response to external stimulus; GO:0022610 biological adhesion; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0009408 response to heat; GO:0050678 regulation of epithelial cell proliferation; GO:0021885 forebrain cell migration; GO:0009719 response to endogenous stimulus; GO:0007155 cell adhesion; GO:0050921 positive regulation of chemotaxis; GO:1902229 regulation of intrinsic apoptotic signaling pathway in response to DNA damage; GO:0044419 interspecies interaction between organisms; GO:1901652 response to peptide; GO:0007399 nervous system development; GO:0031346 positive regulation of cell projection organization; GO:0045773 positive regulation of axon extension; GO:0043269 regulation of ion transport; GO:0048812 neuron projection morphogenesis; GO:0051272 positive regulation of cellular component movement; GO:2000146 negative regulation of cell motility; GO:0032501 multicellular organismal process; GO:0001938 positive regulation of endothelial cell proliferation; GO:0000902 cell morphogenesis; GO:0022029 telencephalon cell migration; GO:0048513 animal organ development; GO:2001021 negative regulation of response to DNA damage stimulus; GO:0007417 central nervous system development; GO:0042330 taxis; GO:0002682 regulation of immune system process; GO:0002685 regulation of leukocyte migration; GO:0071677 positive regulation of mononuclear cell migration; GO:0003013 circulatory system process; GO:0051094 positive regulation of developmental process; GO:0044708 single-organism behavior; GO:1902903 regulation of supramolecular fiber organization; GO:0051047 positive regulation of secretion; GO:0050794 regulation of cellular process; GO:0007162 negative regulation of cell adhesion; GO:0042127 regulation of cell proliferation; GO:2001020 regulation of response to DNA damage stimulus; GO:0009628 response to abiotic stimulus; GO:0032956 regulation of actin cytoskeleton organization; GO:0043067 regulation of programmed cell death; GO:2000147 positive regulation of cell motility; GO:0060326 cell chemotaxis; GO:1902667 regulation of axon guidance; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:0051239 regulation of multicellular organismal process; GO:0045597 positive regulation of cell differentiation; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0007409 axonogenesis; GO:0030900 forebrain development; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:1902531 regulation of intracellular signal transduction; GO:0048731 system development; GO:0050927 positive regulation of positive chemotaxis; GO:0030334 regulation of cell migration; GO:1902669 positive regulation of axon guidance; GO:0050770 regulation of axonogenesis; GO:0030155 regulation of cell adhesion; GO:0008064 regulation of actin polymerization or depolymerization; GO:0030182 neuron differentiation; GO:0043270 positive regulation of ion transport; GO:0002691 regulation of cellular extravasation; GO:0030516 regulation of axon extension; GO:0010976 positive regulation of neuron projection development; GO:0097485 neuron projection guidance; GO:0006873 cellular ion homeostasis; GO:0061387 regulation of extent of cell growth; GO:0006928 movement of cell or subcellular component; GO:0050769 positive regulation of neurogenesis; GO:0036293 response to decreased oxygen levels; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0045666 positive regulation of neuron differentiation; GO:0072503 cellular divalent inorganic cation homeostasis; GO:0022008 neurogenesis; GO:0044764 multi-organism cellular process; GO:0048841 regulation of axon extension involved in axon guidance; GO:0051130 positive regulation of cellular component organization; GO:2001233 regulation of apoptotic signaling pathway; GO:0050433 regulation of catecholamine secretion; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0070098 chemokine-mediated signaling pathway; GO:2001243 negative regulation of intrinsic apoptotic signaling pathway; GO:2000404 regulation of T cell migration; GO:0032103 positive regulation of response to external stimulus; GO:0060322 head development; GO:0009314 response to radiation; GO:0010720 positive regulation of cell development; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0048639 positive regulation of developmental growth; GO:0050801 ion homeostasis; GO:0055074 calcium ion homeostasis; GO:0051962 positive regulation of nervous system development; GO:0048522 positive regulation of cellular process; GO:0002688 regulation of leukocyte chemotaxis; GO:0019725 cellular homeostasis; GO:0051050 positive regulation of transport; GO:0002683 negative regulation of immune system process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0043434 response to peptide hormone; GO:0030030 cell projection organization; GO:1903532 positive regulation of secretion by cell; GO:0040011 locomotion; GO:0048856 anatomical structure development; GO:0072507 divalent inorganic cation homeostasis; GO:2000026 regulation of multicellular organismal development; GO:0051271 negative regulation of cellular component movement; GO:1904994 regulation of leukocyte adhesion to vascular endothelial cell; GO:0008344 adult locomotory behavior; GO:0090025 regulation of monocyte chemotaxis; GO:0030003 cellular cation homeostasis; GO:0031344 regulation of cell projection organization; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0007411 axon guidance; GO:0048468 cell development; GO:2000406 positive regulation of T cell migration; GO:0055082 cellular chemical homeostasis; GO:0051952 regulation of amine transport; GO:0009266 response to temperature stimulus; GO:1903237 negative regulation of leukocyte tethering or rolling; GO:0009987 cellular process; GO:0002692 negative regulation of cellular extravasation; GO:0050918 positive chemotaxis; GO:0003008 system process; GO:0048585 negative regulation of response to stimulus; GO:0031175 neuron projection development; GO:0048518 positive regulation of biological process; GO:0061564 axon development; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:2001242 regulation of intrinsic apoptotic signaling pathway; GO:0090066 regulation of anatomical structure size; GO:0006875 cellular metal ion homeostasis; GO:0051128 regulation of cellular component organization; GO:0009725 response to hormone; GO:0040012 regulation of locomotion; GO:0022604 regulation of cell morphogenesis; GO:0065007 biological regulation; GO:0050679 positive regulation of epithelial cell proliferation; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0009897 external side of plasma membrane; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0009986 cell surface; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0098552 side of membrane; ","GO:0008083 growth factor activity; GO:0005125 cytokine activity; GO:0045236 CXCR chemokine receptor binding; GO:0005102 receptor binding; GO:0005488 binding; GO:0042379 chemokine receptor binding; GO:0005126 cytokine receptor binding; GO:0001664 G-protein coupled receptor binding; GO:0005515 protein binding; GO:0008009 chemokine activity; GO:0042056 chemoattractant activity; ","K10031","CXCL12; C-X-C motif chemokine 12","hsa04672 Intestinal immune network for IgA production - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa05323 Rheumatoid arthritis - Homo sapiens (human); hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human); hsa04670 Leukocyte transendothelial migration - Homo sapiens (human); hsa04360 Axon guidance - Homo sapiens (human); hsa04062 Chemokine signaling pathway - Homo sapiens (human); hsa04064 NF-kappa B signaling pathway - Homo sapiens (human); ","IPR033899; IPR001811; ","CXC Chemokine domain; Chemokine interleukin-8-like domain; \r"]
["P48444","Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1","ARCN1",57.21,70.936,33.3,18,28,18,1.012,1.018,0.999,0.997,0.974,0.988,0.977,0.0561,"mitochondria\r","GO:0046907 intracellular transport; GO:0044707 single-multicellular organism process; GO:0021700 developmental maturation; GO:0008344 adult locomotory behavior; GO:0007420 brain development; GO:0048193 Golgi vesicle transport; GO:0044699 single-organism process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0007610 behavior; GO:0051649 establishment of localization in cell; GO:0006886 intracellular protein transport; GO:0060322 head development; GO:0007275 multicellular organism development; GO:0034613 cellular protein localization; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0030534 adult behavior; GO:0030902 hindbrain development; GO:0021626 central nervous system maturation; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0071702 organic substance transport; GO:0032501 multicellular organismal process; GO:0021590 cerebellum maturation; GO:0021691 cerebellar Purkinje cell layer maturation; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:0021549 cerebellum development; GO:0021680 cerebellar Purkinje cell layer development; GO:0070727 cellular macromolecule localization; GO:0048513 animal organ development; GO:0006890 retrograde vesicle-mediated transport, Golgi to ER; GO:0007417 central nervous system development; GO:0044767 single-organism developmental process; GO:0043473 pigmentation; GO:0007626 locomotory behavior; GO:0022037 metencephalon development; GO:0021695 cerebellar cortex development; GO:0051179 localization; GO:0021578 hindbrain maturation; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0048856 anatomical structure development; GO:0044708 single-organism behavior; GO:0071695 anatomical structure maturation; GO:0021699 cerebellar cortex maturation; ","GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0098796 membrane protein complex; GO:0030137 COPI-coated vesicle; GO:0030660 Golgi-associated vesicle membrane; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0030120 vesicle coat; GO:0030663 COPI-coated vesicle membrane; GO:0005623 cell; GO:0030662 coated vesicle membrane; GO:0044422 organelle part; GO:0030126 COPI vesicle coat; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0044431 Golgi apparatus part; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0048475 coated membrane; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0005829 cytosol; GO:0030135 coated vesicle; GO:0005798 Golgi-associated vesicle; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044432 endoplasmic reticulum part; GO:0030117 membrane coat; GO:0030133 transport vesicle; GO:0043234 protein complex; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; ","K20471",null,null,"IPR028565; IPR011012; IPR022775; ","\"Mu homology domain; Longin-like domain; AP complex, mu/sigma subunit; \"\r"]
["P48506","Glutamate--cysteine ligase catalytic subunit OS=Homo sapiens OX=9606 GN=GCLC","GCLC",72.765,32.517,15.4,9,14,8,0.833,0.986,0.982,1.065,1.105,1.06,1.153,0.0635,"cytoplasm\r","GO:0010941 regulation of cell death; GO:0065008 regulation of biological quality; GO:0006518 peptide metabolic process; GO:0032270 positive regulation of cellular protein metabolic process; GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0042593 glucose homeostasis; GO:0043523 regulation of neuron apoptotic process; GO:0042398 cellular modified amino acid biosynthetic process; GO:0070555 response to interleukin-1; GO:0009749 response to glucose; GO:0046685 response to arsenic-containing substance; GO:0044237 cellular metabolic process; GO:0044272 sulfur compound biosynthetic process; GO:0044752 response to human chorionic gonadotropin; GO:2000490 negative regulation of hepatic stellate cell activation; GO:0051900 regulation of mitochondrial depolarization; GO:1903364 positive regulation of cellular protein catabolic process; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0009408 response to heat; GO:0071333 cellular response to glucose stimulus; GO:0001678 cellular glucose homeostasis; GO:0071322 cellular response to carbohydrate stimulus; GO:0009719 response to endogenous stimulus; GO:0070848 response to growth factor; GO:0009743 response to carbohydrate; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:1901652 response to peptide; GO:1903362 regulation of cellular protein catabolic process; GO:0006790 sulfur compound metabolic process; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0071214 cellular response to abiotic stimulus; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0044281 small molecule metabolic process; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0005975 carbohydrate metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:2001234 negative regulation of apoptotic signaling pathway; GO:1903506 regulation of nucleic acid-templated transcription; GO:0010243 response to organonitrogen compound; GO:0014823 response to activity; GO:0097069 cellular response to thyroxine stimulus; GO:0032269 negative regulation of cellular protein metabolic process; GO:0044710 single-organism metabolic process; GO:0071230 cellular response to amino acid stimulus; GO:0048583 regulation of response to stimulus; GO:0034284 response to monosaccharide; GO:0061136 regulation of proteasomal protein catabolic process; GO:0032869 cellular response to insulin stimulus; GO:1901698 response to nitrogen compound; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0003013 circulatory system process; GO:0060548 negative regulation of cell death; GO:0043436 oxoacid metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0050880 regulation of blood vessel size; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0045454 cell redox homeostasis; GO:1901700 response to oxygen-containing compound; GO:0043067 regulation of programmed cell death; GO:0003018 vascular process in circulatory system; GO:0003254 regulation of membrane depolarization; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0032844 regulation of homeostatic process; GO:0045892 negative regulation of transcription, DNA-templated; GO:0050866 negative regulation of cell activation; GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0035728 response to hepatocyte growth factor; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0009410 response to xenobiotic stimulus; GO:0043524 negative regulation of neuron apoptotic process; GO:0071229 cellular response to acid chemical; GO:0009889 regulation of biosynthetic process; GO:0009896 positive regulation of catabolic process; GO:0071774 response to fibroblast growth factor; GO:0033500 carbohydrate homeostasis; GO:0051171 regulation of nitrogen compound metabolic process; GO:0042176 regulation of protein catabolic process; GO:0035150 regulation of tube size; GO:0009966 regulation of signal transduction; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0097067 cellular response to thyroid hormone stimulus; GO:0006767 water-soluble vitamin metabolic process; GO:0048878 chemical homeostasis; GO:0019852 L-ascorbic acid metabolic process; GO:1901215 negative regulation of neuron death; GO:0006950 response to stress; GO:1904386 response to L-phenylalanine derivative; GO:0071371 cellular response to gonadotropin stimulus; GO:0071407 cellular response to organic cyclic compound; GO:2001237 negative regulation of extrinsic apoptotic signaling pathway; GO:0071496 cellular response to external stimulus; GO:0030162 regulation of proteolysis; GO:0010033 response to organic substance; GO:0007584 response to nutrient; GO:1901605 alpha-amino acid metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:1903321 negative regulation of protein modification by small protein conjugation or removal; GO:0009890 negative regulation of biosynthetic process; GO:0071326 cellular response to monosaccharide stimulus; GO:0051247 positive regulation of protein metabolic process; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0012501 programmed cell death; GO:1901564 organonitrogen compound metabolic process; GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process; GO:0001101 response to acid chemical; GO:0071331 cellular response to hexose stimulus; GO:0009746 response to hexose; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0031331 positive regulation of cellular catabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0071363 cellular response to growth factor stimulus; GO:0051253 negative regulation of RNA metabolic process; GO:0031400 negative regulation of protein modification process; GO:0000096 sulfur amino acid metabolic process; GO:0031396 regulation of protein ubiquitination; GO:2001233 regulation of apoptotic signaling pathway; GO:2001141 regulation of RNA biosynthetic process; GO:0035729 cellular response to hepatocyte growth factor stimulus; GO:0051409 response to nitrosative stress; GO:0010646 regulation of cell communication; GO:0006520 cellular amino acid metabolic process; GO:1901653 cellular response to peptide; GO:0009893 positive regulation of metabolic process; GO:0007005 mitochondrion organization; GO:0006915 apoptotic process; GO:0006979 response to oxidative stress; GO:0006749 glutathione metabolic process; GO:0006534 cysteine metabolic process; GO:0046686 response to cadmium ion; GO:0097066 response to thyroid hormone; GO:0010035 response to inorganic substance; GO:0070887 cellular response to chemical stimulus; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0032502 developmental process; GO:0043200 response to amino acid; GO:0010468 regulation of gene expression; GO:0034097 response to cytokine; GO:0031326 regulation of cellular biosynthetic process; GO:0043043 peptide biosynthetic process; GO:0048522 positive regulation of cellular process; GO:0019725 cellular homeostasis; GO:0043603 cellular amide metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0010038 response to metal ion; GO:0042391 regulation of membrane potential; GO:0071417 cellular response to organonitrogen compound; GO:0044723 single-organism carbohydrate metabolic process; GO:0032868 response to insulin; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0050865 regulation of cell activation; GO:0043434 response to peptide hormone; GO:0009069 serine family amino acid metabolic process; GO:1901699 cellular response to nitrogen compound; GO:0032870 cellular response to hormone stimulus; GO:0007568 aging; GO:1902679 negative regulation of RNA biosynthetic process; GO:2001236 regulation of extrinsic apoptotic signaling pathway; GO:0019222 regulation of metabolic process; GO:0006082 organic acid metabolic process; GO:0019184 nonribosomal peptide biosynthetic process; GO:2000489 regulation of hepatic stellate cell activation; GO:0016043 cellular component organization; GO:0043648 dicarboxylic acid metabolic process; GO:0071260 cellular response to mechanical stimulus; GO:0043069 negative regulation of programmed cell death; GO:2000021 regulation of ion homeostasis; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0071310 cellular response to organic substance; GO:0097068 response to thyroxine; GO:0031324 negative regulation of cellular metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:1904387 cellular response to L-phenylalanine derivative; GO:0050896 response to stimulus; GO:0055082 cellular chemical homeostasis; GO:0071704 organic substance metabolic process; GO:0034698 response to gonadotropin; GO:0009991 response to extracellular stimulus; GO:0042592 homeostatic process; GO:0009612 response to mechanical stimulus; GO:0006766 vitamin metabolic process; GO:0045862 positive regulation of proteolysis; GO:0006575 cellular modified amino acid metabolic process; GO:0043066 negative regulation of apoptotic process; GO:0071375 cellular response to peptide hormone stimulus; GO:0032354 response to follicle-stimulating hormone; GO:0009266 response to temperature stimulus; GO:0005996 monosaccharide metabolic process; GO:0006536 glutamate metabolic process; GO:0008015 blood circulation; GO:0034641 cellular nitrogen compound metabolic process; GO:0009987 cellular process; GO:1901214 regulation of neuron death; GO:0031397 negative regulation of protein ubiquitination; GO:0009064 glutamine family amino acid metabolic process; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0003008 system process; GO:0006355 regulation of transcription, DNA-templated; GO:0008637 apoptotic mitochondrial changes; GO:0010629 negative regulation of gene expression; GO:1901800 positive regulation of proteasomal protein catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0071372 cellular response to follicle-stimulating hormone stimulus; GO:1901701 cellular response to oxygen-containing compound; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0071495 cellular response to endogenous stimulus; GO:0051246 regulation of protein metabolic process; GO:0044344 cellular response to fibroblast growth factor stimulus; GO:0019752 carboxylic acid metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0090066 regulation of anatomical structure size; GO:0043604 amide biosynthetic process; GO:0031667 response to nutrient levels; GO:0045732 positive regulation of protein catabolic process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0009725 response to hormone; GO:0006750 glutathione biosynthetic process; GO:0051881 regulation of mitochondrial membrane potential; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:1902494 catalytic complex; GO:0044464 cell part; GO:0005622 intracellular; GO:0017109 glutamate-cysteine ligase complex; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:0016597 amino acid binding; GO:1901265 nucleoside phosphate binding; GO:0046983 protein dimerization activity; GO:0016874 ligase activity; GO:0005515 protein binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0031406 carboxylic acid binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043531 ADP binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0017076 purine nucleotide binding; GO:0000287 magnesium ion binding; GO:0005524 ATP binding; GO:0046982 protein heterodimerization activity; GO:0004357 glutamate-cysteine ligase activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0043177 organic acid binding; GO:0000166 nucleotide binding; GO:0016881 acid-amino acid ligase activity; GO:0048037 cofactor binding; GO:0016879 ligase activity, forming carbon-nitrogen bonds; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016595 glutamate binding; GO:0046872 metal ion binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0050662 coenzyme binding; GO:0036094 small molecule binding; ","K11204","GCLC; glutamate--cysteine ligase catalytic subunit [EC:6.3.2.2]","hsa00480 Glutathione metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00270 Cysteine and methionine metabolism - Homo sapiens (human); hsa04216 Ferroptosis - Homo sapiens (human); "]
["P48594","Serpin B4 OS=Homo sapiens OX=9606 GN=SERPINB4","SERPINB4",44.853,142.02,50.3,21,64,10,0.247,0.251,0.224,1.676,1.684,1.711,7.024,3.51e-07,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0010951 negative regulation of endopeptidase activity; GO:0031341 regulation of cell killing; GO:0060255 regulation of macromolecule metabolic process; GO:0002698 negative regulation of immune effector process; GO:0002704 negative regulation of leukocyte mediated immunity; GO:0002715 regulation of natural killer cell mediated immunity; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0031347 regulation of defense response; GO:0002706 regulation of lymphocyte mediated immunity; GO:0051346 negative regulation of hydrolase activity; GO:0045953 negative regulation of natural killer cell mediated cytotoxicity; GO:0010466 negative regulation of peptidase activity; GO:0045088 regulation of innate immune response; GO:0002707 negative regulation of lymphocyte mediated immunity; GO:0050777 negative regulation of immune response; GO:0002697 regulation of immune effector process; GO:0031348 negative regulation of defense response; GO:0052548 regulation of endopeptidase activity; GO:0045861 negative regulation of proteolysis; GO:0001910 regulation of leukocyte mediated cytotoxicity; GO:0080090 regulation of primary metabolic process; GO:0031342 negative regulation of cell killing; GO:0002716 negative regulation of natural killer cell mediated immunity; GO:0048585 negative regulation of response to stimulus; GO:0030162 regulation of proteolysis; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0009892 negative regulation of metabolic process; GO:0050776 regulation of immune response; GO:0002683 negative regulation of immune system process; GO:0002703 regulation of leukocyte mediated immunity; GO:0045824 negative regulation of innate immune response; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0051246 regulation of protein metabolic process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0048583 regulation of response to stimulus; GO:0042269 regulation of natural killer cell mediated cytotoxicity; GO:0065009 regulation of molecular function; GO:0051248 negative regulation of protein metabolic process; GO:0019222 regulation of metabolic process; GO:0002682 regulation of immune system process; GO:0044092 negative regulation of molecular function; GO:0042270 protection from natural killer cell mediated cytotoxicity; GO:0001911 negative regulation of leukocyte mediated cytotoxicity; GO:0052547 regulation of peptidase activity; GO:0065007 biological regulation; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:0002020 protease binding; GO:0004867 serine-type endopeptidase inhibitor activity; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0030414 peptidase inhibitor activity; GO:0061134 peptidase regulator activity; GO:0061135 endopeptidase regulator activity; GO:0005515 protein binding; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0004866 endopeptidase inhibitor activity; GO:0019899 enzyme binding; ","K13963","SERPINB; serpin B","hsa05146 Amoebiasis - Homo sapiens (human); ","IPR023796; ","Serpin domain; \r"]
["P48637","Glutathione synthetase OS=Homo sapiens OX=9606 GN=GSS","GSS",52.384,67.587,30,15,18,15,1.044,1.023,0.997,0.984,1,0.978,0.967,0.0862,"cytoplasm\r","GO:0044707 single-multicellular organism process; GO:0001101 response to acid chemical; GO:0006518 peptide metabolic process; GO:1901700 response to oxygen-containing compound; GO:0042398 cellular modified amino acid biosynthetic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0044272 sulfur compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0009605 response to external stimulus; GO:0009991 response to extracellular stimulus; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0006575 cellular modified amino acid metabolic process; GO:0009410 response to xenobiotic stimulus; GO:0006979 response to oxidative stress; GO:0006749 glutathione metabolic process; GO:0046686 response to cadmium ion; GO:0009719 response to endogenous stimulus; GO:0034641 cellular nitrogen compound metabolic process; GO:0034612 response to tumor necrosis factor; GO:0010035 response to inorganic substance; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0006790 sulfur compound metabolic process; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0043200 response to amino acid; GO:0034097 response to cytokine; GO:0006950 response to stress; GO:0043043 peptide biosynthetic process; GO:0048731 system development; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0032501 multicellular organismal process; GO:0044249 cellular biosynthetic process; GO:0010038 response to metal ion; GO:0010243 response to organonitrogen compound; GO:0042221 response to chemical; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0044767 single-organism developmental process; GO:0044710 single-organism metabolic process; GO:0007568 aging; GO:1901698 response to nitrogen compound; GO:0019752 carboxylic acid metabolic process; GO:0043604 amide biosynthetic process; GO:0031667 response to nutrient levels; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:0019184 nonribosomal peptide biosynthetic process; GO:0006750 glutathione biosynthetic process; GO:0043436 oxoacid metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016597 amino acid binding; GO:1901265 nucleoside phosphate binding; GO:0004363 glutathione synthase activity; GO:0046983 protein dimerization activity; GO:0016874 ligase activity; GO:0005515 protein binding; GO:0043295 glutathione binding; GO:1900750 oligopeptide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0042802 identical protein binding; GO:0031406 carboxylic acid binding; GO:0042277 peptide binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0000287 magnesium ion binding; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0043177 organic acid binding; GO:0016594 glycine binding; GO:0033218 amide binding; GO:0000166 nucleotide binding; GO:0016881 acid-amino acid ligase activity; GO:1901681 sulfur compound binding; GO:0016879 ligase activity, forming carbon-nitrogen bonds; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0072341 modified amino acid binding; GO:0042803 protein homodimerization activity; GO:0046872 metal ion binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; ","K01920",null,null,"IPR016185; IPR014709; IPR014049; IPR014042; IPR004887; ","\"Pre-ATP-grasp domain; Glutathione synthase domain; Glutathione synthase, N-terminal, eukaryotic; Glutathione synthase, alpha-helical, eukaryotic; Glutathione synthase, substrate-binding, eukaryotic; \"\r"]
["P48729","Casein kinase I isoform alpha OS=Homo sapiens OX=9606 GN=CSNK1A1","CSNK1A1",38.914,14.216,16.9,5,7,5,0.888,0.866,0.868,1.157,1.153,1.113,1.305,5.76e-05,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0007166 cell surface receptor signaling pathway; GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0044237 cellular metabolic process; GO:1903364 positive regulation of cellular protein catabolic process; GO:0008152 metabolic process; GO:0065003 macromolecular complex assembly; GO:0008360 regulation of cell shape; GO:0018105 peptidyl-serine phosphorylation; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0016055 Wnt signaling pathway; GO:1903362 regulation of cellular protein catabolic process; GO:0044765 single-organism transport; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:1904886 beta-catenin destruction complex disassembly; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0060828 regulation of canonical Wnt signaling pathway; GO:0031323 regulation of cellular metabolic process; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0007267 cell-cell signaling; GO:0007030 Golgi organization; GO:0030163 protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0061136 regulation of proteasomal protein catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0051301 cell division; GO:0050794 regulation of cellular process; GO:0016310 phosphorylation; GO:0044267 cellular protein metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:1903047 mitotic cell cycle process; GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0023057 negative regulation of signaling; GO:1902578 single-organism localization; GO:0010648 negative regulation of cell communication; GO:0009896 positive regulation of catabolic process; GO:0044248 cellular catabolic process; GO:0042176 regulation of protein catabolic process; GO:0007010 cytoskeleton organization; GO:0009966 regulation of signal transduction; GO:0006461 protein complex assembly; GO:0045104 intermediate filament cytoskeleton organization; GO:0045103 intermediate filament-based process; GO:0016192 vesicle-mediated transport; GO:0032984 macromolecular complex disassembly; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0051247 positive regulation of protein metabolic process; GO:0030111 regulation of Wnt signaling pathway; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0000280 nuclear division; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0043412 macromolecule modification; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process; GO:0010256 endomembrane system organization; GO:0009968 negative regulation of signal transduction; GO:0018209 peptidyl-serine modification; GO:0031331 positive regulation of cellular catabolic process; GO:0007067 mitotic nuclear division; GO:0023051 regulation of signaling; GO:0090090 negative regulation of canonical Wnt signaling pathway; GO:0044699 single-organism process; GO:0006796 phosphate-containing compound metabolic process; GO:0006909 phagocytosis; GO:0051234 establishment of localization; GO:0043241 protein complex disassembly; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0022607 cellular component assembly; GO:0060070 canonical Wnt signaling pathway; GO:1904885 beta-catenin destruction complex assembly; GO:0030178 negative regulation of Wnt signaling pathway; GO:0071822 protein complex subunit organization; GO:1904424 regulation of GTP binding; GO:0051098 regulation of binding; GO:0048522 positive regulation of cellular process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0023052 signaling; GO:0198738 cell-cell signaling by wnt; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0036211 protein modification process; GO:0070271 protein complex biogenesis; GO:0016043 cellular component organization; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0048285 organelle fission; GO:0050896 response to stimulus; GO:0010498 proteasomal protein catabolic process; GO:0071704 organic substance metabolic process; GO:0045862 positive regulation of proteolysis; GO:0006468 protein phosphorylation; GO:0006508 proteolysis; GO:0009987 cellular process; GO:0043632 modification-dependent macromolecule catabolic process; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0019941 modification-dependent protein catabolic process; GO:1901800 positive regulation of proteasomal protein catabolic process; GO:0048585 negative regulation of response to stimulus; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0043933 macromolecular complex subunit organization; GO:0018193 peptidyl-amino acid modification; GO:0051246 regulation of protein metabolic process; GO:0009057 macromolecule catabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0022411 cellular component disassembly; GO:0022402 cell cycle process; GO:0045732 positive regulation of protein catabolic process; GO:0051128 regulation of cellular component organization; GO:0009056 catabolic process; GO:0022604 regulation of cell morphogenesis; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0030877 beta-catenin destruction complex; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0000777 condensed chromosome kinetochore; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0044427 chromosomal part; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0000793 condensed chromosome; GO:0005654 nucleoplasm; GO:0005815 microtubule organizing center; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0016607 nuclear speck; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0000776 kinetochore; GO:0043233 organelle lumen; GO:0005929 cilium; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0000779 condensed chromosome, centromeric region; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0043231 intracellular membrane-bounded organelle; GO:0098687 chromosomal region; GO:0043226 organelle; GO:0005634 nucleus; GO:0005813 centrosome; GO:0000775 chromosome, centromeric region; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0004672 protein kinase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016301 kinase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0004674 protein serine/threonine kinase activity; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K08957","CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]","hsa05225 Hepatocellular carcinoma - Homo sapiens (human); hsa04340 Hedgehog signaling pathway - Homo sapiens (human); hsa05226 Gastric cancer - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa05224 Breast cancer - Homo sapiens (human); hsa04310 Wnt signaling pathway - Homo sapiens (human); ","IPR000719; IPR011009; ","Protein kinase domain; Protein kinase-like domain; \r"]
["P48735","Isocitrate dehydrogenase [NADP], mitochondrial OS=Homo sapiens OX=9606 GN=IDH2","IDH2",50.909,149.23,47.3,24,61,23,1.038,1.035,1.099,0.96,0.961,0.977,0.914,0.0115,"mitochondria\r","GO:1903975 regulation of glial cell migration; GO:0019362 pyridine nucleotide metabolic process; GO:0014013 regulation of gliogenesis; GO:1904464 regulation of matrix metallopeptidase secretion; GO:0044237 cellular metabolic process; GO:0008285 negative regulation of cell proliferation; GO:0072525 pyridine-containing compound biosynthetic process; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0044262 cellular carbohydrate metabolic process; GO:0032879 regulation of localization; GO:0032787 monocarboxylic acid metabolic process; GO:0009108 coenzyme biosynthetic process; GO:0046487 glyoxylate metabolic process; GO:0007399 nervous system development; GO:0051051 negative regulation of transport; GO:0072350 tricarboxylic acid metabolic process; GO:0018130 heterocycle biosynthetic process; GO:0050709 negative regulation of protein secretion; GO:0048699 generation of neurons; GO:0044281 small molecule metabolic process; GO:1903531 negative regulation of secretion by cell; GO:0044763 single-organism cellular process; GO:0006081 cellular aldehyde metabolic process; GO:0006732 coenzyme metabolic process; GO:0019359 nicotinamide nucleotide biosynthetic process; GO:2000146 negative regulation of cell motility; GO:0005975 carbohydrate metabolic process; GO:0032501 multicellular organismal process; GO:0050768 negative regulation of neurogenesis; GO:0090407 organophosphate biosynthetic process; GO:0060251 regulation of glial cell proliferation; GO:0044710 single-organism metabolic process; GO:0051223 regulation of protein transport; GO:0010721 negative regulation of cell development; GO:1901362 organic cyclic compound biosynthetic process; GO:0043436 oxoacid metabolic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0006097 glyoxylate cycle; GO:0042127 regulation of cell proliferation; GO:0046496 nicotinamide nucleotide metabolic process; GO:0006741 NADP biosynthetic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0051239 regulation of multicellular organismal process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:2000145 regulation of cell motility; GO:0007275 multicellular organism development; GO:0032880 regulation of protein localization; GO:0044711 single-organism biosynthetic process; GO:0051270 regulation of cellular component movement; GO:0051224 negative regulation of protein transport; GO:0048731 system development; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0006099 tricarboxylic acid cycle; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0030334 regulation of cell migration; GO:0006102 isocitrate metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0030336 negative regulation of cell migration; GO:0006793 phosphorus metabolic process; GO:0019637 organophosphate metabolic process; GO:0050793 regulation of developmental process; GO:1901564 organonitrogen compound metabolic process; GO:0051188 cofactor biosynthetic process; GO:0006739 NADP metabolic process; GO:0051093 negative regulation of developmental process; GO:0009117 nucleotide metabolic process; GO:0048869 cellular developmental process; GO:0051046 regulation of secretion; GO:0044699 single-organism process; GO:0051241 negative regulation of multicellular organismal process; GO:0022008 neurogenesis; GO:0009058 biosynthetic process; GO:0019363 pyridine nucleotide biosynthetic process; GO:0072524 pyridine-containing compound metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0040013 negative regulation of locomotion; GO:0006753 nucleoside phosphate metabolic process; GO:0006103 2-oxoglutarate metabolic process; GO:0045596 negative regulation of cell differentiation; GO:1904465 negative regulation of matrix metallopeptidase secretion; GO:0032502 developmental process; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0055114 oxidation-reduction process; GO:1901360 organic cyclic compound metabolic process; GO:1903530 regulation of secretion by cell; GO:0051186 cofactor metabolic process; GO:0006101 citrate metabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0051048 negative regulation of secretion; GO:0050789 regulation of biological process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:0051271 negative regulation of cellular component movement; GO:2000026 regulation of multicellular organismal development; GO:0043648 dicarboxylic acid metabolic process; GO:0009165 nucleotide biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0070201 regulation of establishment of protein localization; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0051961 negative regulation of nervous system development; GO:0034641 cellular nitrogen compound metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0050708 regulation of protein secretion; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0051049 regulation of transport; GO:0006807 nitrogen compound metabolic process; GO:0045333 cellular respiration; GO:0044249 cellular biosynthetic process; GO:0014014 negative regulation of gliogenesis; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0060253 negative regulation of glial cell proliferation; GO:0009060 aerobic respiration; GO:0044767 single-organism developmental process; GO:0019752 carboxylic acid metabolic process; GO:1904950 negative regulation of establishment of protein localization; GO:1903976 negative regulation of glial cell migration; GO:0040012 regulation of locomotion; GO:0065007 biological regulation; GO:0050767 regulation of neurogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0042579 microbody; GO:0019866 organelle inner membrane; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005759 mitochondrial matrix; GO:0044429 mitochondrial part; GO:0005777 peroxisome; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031975 envelope; GO:0031966 mitochondrial membrane; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0000287 magnesium ion binding; GO:1901265 nucleoside phosphate binding; GO:0043167 ion binding; GO:0004448 isocitrate dehydrogenase activity; GO:0000166 nucleotide binding; GO:0048037 cofactor binding; GO:0016491 oxidoreductase activity; GO:0016614 oxidoreductase activity, acting on CH-OH group of donors; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; GO:0003824 catalytic activity; GO:0051287 NAD binding; GO:0005488 binding; GO:0004450 isocitrate dehydrogenase (NADP+) activity; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0036094 small molecule binding; GO:0050662 coenzyme binding; ","K00031","IDH1; isocitrate dehydrogenase [EC:1.1.1.42]","hsa01210 2-Oxocarboxylic acid metabolism - Homo sapiens (human); hsa00480 Glutathione metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00020 Citrate cycle (TCA cycle) - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); hsa05230 Central carbon metabolism in cancer - Homo sapiens (human); hsa04146 Peroxisome - Homo sapiens (human); hsa01230 Biosynthesis of amino acids - Homo sapiens (human); ","IPR024084; ","Isopropylmalate dehydrogenase-like domain; \r"]
["P49023","Paxillin OS=Homo sapiens OX=9606 GN=PXN","PXN",64.505,13.347,5.4,3,3,3,0.967,0.971,0.958,1.05,1.038,1.02,1.073,1.64E-3,"nucleus\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0003012 muscle system process; GO:0007166 cell surface receptor signaling pathway; GO:0023051 regulation of signaling; GO:0071560 cellular response to transforming growth factor beta stimulus; GO:0044699 single-organism process; GO:0071363 cellular response to growth factor stimulus; GO:0022610 biological adhesion; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:1901653 cellular response to peptide; GO:0007154 cell communication; GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0007160 cell-matrix adhesion; GO:0006979 response to oxidative stress; GO:0007155 cell adhesion; GO:0038127 ERBB signaling pathway; GO:0009719 response to endogenous stimulus; GO:0070848 response to growth factor; GO:0034599 cellular response to oxidative stress; GO:1901652 response to peptide; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0070887 cellular response to chemical stimulus; GO:0051716 cellular response to stimulus; GO:0034614 cellular response to reactive oxygen species; GO:0071822 protein complex subunit organization; GO:0000302 response to reactive oxygen species; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0023052 signaling; GO:0071559 response to transforming growth factor beta; GO:0032501 multicellular organismal process; GO:0071417 cellular response to organonitrogen compound; GO:0010243 response to organonitrogen compound; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0043434 response to peptide hormone; GO:1901699 cellular response to nitrogen compound; GO:0032870 cellular response to hormone stimulus; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0071378 cellular response to growth hormone stimulus; GO:0048010 vascular endothelial growth factor receptor signaling pathway; GO:0070271 protein complex biogenesis; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0016043 cellular component organization; GO:0007172 signal complex assembly; GO:0071310 cellular response to organic substance; GO:1901700 response to oxygen-containing compound; GO:0060396 growth hormone receptor signaling pathway; GO:0007173 epidermal growth factor receptor signaling pathway; GO:0050896 response to stimulus; GO:0006936 muscle contraction; GO:0071375 cellular response to peptide hormone stimulus; GO:0009987 cellular process; GO:0009966 regulation of signal transduction; GO:0006461 protein complex assembly; GO:0043623 cellular protein complex assembly; GO:0034622 cellular macromolecular complex assembly; GO:0003008 system process; GO:0006950 response to stress; GO:0007179 transforming growth factor beta receptor signaling pathway; GO:0010033 response to organic substance; GO:0060416 response to growth hormone; GO:0043933 macromolecular complex subunit organization; GO:1901701 cellular response to oxygen-containing compound; GO:0031589 cell-substrate adhesion; GO:0071495 cellular response to endogenous stimulus; GO:0009725 response to hormone; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0005938 cell cortex; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0099568 cytoplasmic region; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0032432 actin filament bundle; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0005925 focal adhesion; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0030027 lamellipodium; GO:0005912 adherens junction; GO:0001725 stress fiber; GO:0030055 cell-substrate junction; GO:0042641 actomyosin; GO:0005924 cell-substrate adherens junction; GO:0043229 intracellular organelle; GO:0031252 cell leading edge; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0097517 contractile actin filament bundle; GO:0005875 microtubule associated complex; GO:0005829 cytosol; GO:0015629 actin cytoskeleton; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0031625 ubiquitin protein ligase binding; GO:0005102 receptor binding; GO:0043167 ion binding; GO:0044877 macromolecular complex binding; GO:0019901 protein kinase binding; GO:0005515 protein binding; GO:0005178 integrin binding; GO:0008270 zinc ion binding; GO:0019900 kinase binding; GO:0050839 cell adhesion molecule binding; GO:0008092 cytoskeletal protein binding; GO:0046914 transition metal ion binding; GO:0017166 vinculin binding; GO:0005488 binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0019899 enzyme binding; GO:0008013 beta-catenin binding; GO:0032403 protein complex binding; ","K05760","PXN; paxillin","hsa05100 Bacterial invasion of epithelial cells - Homo sapiens (human); hsa04370 VEGF signaling pathway - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa05203 Viral carcinogenesis - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa04670 Leukocyte transendothelial migration - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa04062 Chemokine signaling pathway - Homo sapiens (human); ","IPR001781; ","\"Zinc finger, LIM-type; \"\r"]
["P49189","4-trimethylaminobutyraldehyde dehydrogenase OS=Homo sapiens OX=9606 GN=ALDH9A1","ALDH9A1",53.801,173.57,41.3,20,45,20,1.129,1.111,1.118,0.901,0.899,0.888,0.8,2.18e-06,"cytoplasm\r","GO:0001505 regulation of neurotransmitter levels; GO:0042445 hormone metabolic process; GO:0065008 regulation of biological quality; GO:0055114 oxidation-reduction process; GO:0044763 single-organism cellular process; GO:0006578 amino-acid betaine biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0097164 ammonium ion metabolic process; GO:0006081 cellular aldehyde metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0045329 carnitine biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0006577 amino-acid betaine metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044237 cellular metabolic process; GO:0044249 cellular biosynthetic process; GO:0071704 organic substance metabolic process; GO:0042136 neurotransmitter biosynthetic process; GO:0008152 metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0044710 single-organism metabolic process; GO:0042133 neurotransmitter metabolic process; GO:0010817 regulation of hormone levels; GO:0034641 cellular nitrogen compound metabolic process; GO:0009437 carnitine metabolic process; GO:0009987 cellular process; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0004028 3-chloroallyl aldehyde dehydrogenase activity; GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; GO:0047105 4-trimethylammoniobutyraldehyde dehydrogenase activity; GO:0003824 catalytic activity; GO:0019145 aminobutyraldehyde dehydrogenase activity; GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors; GO:0033737 1-pyrroline dehydrogenase activity; GO:0016491 oxidoreductase activity; GO:0004029 aldehyde dehydrogenase (NAD) activity; ","K00149","ALDH9A1; aldehyde dehydrogenase family 9 member A1 [EC:1.2.1.47 1.2.1.3]","hsa00280 Valine, leucine and isoleucine degradation - Homo sapiens (human); hsa00310 Lysine degradation - Homo sapiens (human); hsa00053 Ascorbate and aldarate metabolism - Homo sapiens (human); hsa00620 Pyruvate metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00561 Glycerolipid metabolism - Homo sapiens (human); hsa00330 Arginine and proline metabolism - Homo sapiens (human); hsa00340 Histidine metabolism - Homo sapiens (human); hsa00071 Fatty acid degradation - Homo sapiens (human); hsa00410 beta-Alanine metabolism - Homo sapiens (human); hsa00380 Tryptophan metabolism - Homo sapiens (human); hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human); ","IPR016161; IPR015590; IPR016162; IPR016163; ","\"Aldehyde/histidinol dehydrogenase; Aldehyde dehydrogenase domain; Aldehyde dehydrogenase N-terminal domain; Aldehyde dehydrogenase, C-terminal; \"\r"]
["P49257","Protein ERGIC-53 OS=Homo sapiens OX=9606 GN=LMAN1","LMAN1",57.548,93.245,20,9,13,9,1.019,1.07,1.055,0.958,0.906,0.971,0.902,0.0157,"peroxisome\r","GO:0044085 cellular component biogenesis; GO:0043413 macromolecule glycosylation; GO:0006901 vesicle coating; GO:0010256 endomembrane system organization; GO:0048207 vesicle targeting, rough ER to cis-Golgi; GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0048208 COPII vesicle coating; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0018196 peptidyl-asparagine modification; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0006457 protein folding; GO:0009611 response to wounding; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:1901137 carbohydrate derivative biosynthetic process; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0048199 vesicle targeting, to, from or within Golgi; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006487 protein N-linked glycosylation; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0006486 protein glycosylation; GO:0051650 establishment of vesicle localization; GO:0009101 glycoprotein biosynthetic process; GO:0071822 protein complex subunit organization; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0009100 glycoprotein metabolic process; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0010638 positive regulation of organelle organization; GO:0007030 Golgi organization; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0050817 coagulation; GO:0036211 protein modification process; GO:0070271 protein complex biogenesis; GO:0007029 endoplasmic reticulum organization; GO:0050794 regulation of cellular process; GO:0051640 organelle localization; GO:0044707 single-multicellular organism process; GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0044267 cellular protein metabolic process; GO:0048193 Golgi vesicle transport; GO:0006903 vesicle targeting; GO:0050896 response to stimulus; GO:0007599 hemostasis; GO:0071704 organic substance metabolic process; GO:0051648 vesicle localization; GO:1901135 carbohydrate derivative metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0070085 glycosylation; GO:0006461 protein complex assembly; GO:0050878 regulation of body fluid levels; GO:0006950 response to stress; GO:0090114 COPII-coated vesicle budding; GO:0016192 vesicle-mediated transport; GO:0033043 regulation of organelle organization; GO:0016050 vesicle organization; GO:0071702 organic substance transport; GO:0051656 establishment of organelle localization; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0051641 cellular localization; GO:0018193 peptidyl-amino acid modification; GO:0045184 establishment of protein localization; GO:0018279 protein N-linked glycosylation via asparagine; GO:0034645 cellular macromolecule biosynthetic process; GO:0042060 wound healing; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0006900 membrane budding; GO:0051128 regulation of cellular component organization; GO:0043412 macromolecule modification; GO:0051179 localization; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0044216 other organism cell; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0043657 host cell; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0030430 host cell cytoplasm; GO:0043656 intracellular region of host; GO:0033646 host intracellular part; GO:0012506 vesicle membrane; GO:0005576 extracellular region; GO:0030135 coated vesicle; GO:0099081 supramolecular polymer; GO:0033655 host cell cytoplasm part; GO:0043231 intracellular membrane-bounded organelle; GO:0044449 contractile fiber part; GO:0030133 transport vesicle; GO:0043230 extracellular organelle; GO:0044220 host cell perinuclear region of cytoplasm; GO:0030658 transport vesicle membrane; GO:0005783 endoplasmic reticulum; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0031410 cytoplasmic vesicle; GO:0030016 myofibril; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0099512 supramolecular fiber; GO:0018995 host; GO:0030662 coated vesicle membrane; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0043292 contractile fiber; GO:0044431 Golgi apparatus part; GO:0044215 other organism; GO:0012507 ER to Golgi transport vesicle membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0044217 other organism part; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0033643 host cell part; GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0030134 ER to Golgi transport vesicle; GO:0012505 endomembrane system; GO:0016021 integral component of membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0044432 endoplasmic reticulum part; GO:0005793 endoplasmic reticulum-Golgi intermediate compartment; GO:0030017 sarcomere; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:0005488 binding; GO:0043167 ion binding; GO:0005537 mannose binding; GO:0046872 metal ion binding; GO:0030246 carbohydrate binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0051082 unfolded protein binding; GO:0048029 monosaccharide binding; GO:0036094 small molecule binding; ","K10080","LMAN1; lectin, mannose-binding 1","hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); ","IPR005052; IPR013320; ","Legume-like lectin; Concanavalin A-like lectin/glucanase domain; \r"]
["P49327","Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN","FASN",273.42,323.31,40.8,82,200,82,1.259,1.255,1.244,0.758,0.77,0.766,0.61,5.9e-08,"cytoplasm\r","GO:0051188 cofactor biosynthetic process; GO:0001649 osteoblast differentiation; GO:0048732 gland development; GO:0016053 organic acid biosynthetic process; GO:0035337 fatty-acyl-CoA metabolic process; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0009058 biosynthetic process; GO:0071345 cellular response to cytokine stimulus; GO:0044237 cellular metabolic process; GO:0035384 thioester biosynthetic process; GO:0044272 sulfur compound biosynthetic process; GO:0008610 lipid biosynthetic process; GO:0008152 metabolic process; GO:0009893 positive regulation of metabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0009108 coenzyme biosynthetic process; GO:0015939 pantothenate metabolic process; GO:0070887 cellular response to chemical stimulus; GO:0006629 lipid metabolic process; GO:0006790 sulfur compound metabolic process; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0034097 response to cytokine; GO:0071616 acyl-CoA biosynthetic process; GO:0055114 oxidation-reduction process; GO:0001503 ossification; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0035336 long-chain fatty-acyl-CoA metabolic process; GO:0006732 coenzyme metabolic process; GO:0006084 acetyl-CoA metabolic process; GO:0043603 cellular amide metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0006633 fatty acid biosynthetic process; GO:0035338 long-chain fatty-acyl-CoA biosynthetic process; GO:0071353 cellular response to interleukin-4; GO:0032501 multicellular organismal process; GO:0051186 cofactor metabolic process; GO:0046394 carboxylic acid biosynthetic process; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0044710 single-organism metabolic process; GO:0019222 regulation of metabolic process; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:0043436 oxoacid metabolic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0046949 fatty-acyl-CoA biosynthetic process; GO:0071310 cellular response to organic substance; GO:0050896 response to stimulus; GO:0030879 mammary gland development; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0006766 vitamin metabolic process; GO:0006575 cellular modified amino acid metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0070670 response to interleukin-4; GO:0006767 water-soluble vitamin metabolic process; GO:0044711 single-organism biosynthetic process; GO:0048731 system development; GO:0035383 thioester metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0006631 fatty acid metabolic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0006637 acyl-CoA metabolic process; GO:0006793 phosphorus metabolic process; GO:0044767 single-organism developmental process; GO:0031325 positive regulation of cellular metabolic process; GO:0044283 small molecule biosynthetic process; GO:0019752 carboxylic acid metabolic process; GO:0072330 monocarboxylic acid biosynthetic process; GO:0065007 biological regulation; GO:1901564 organonitrogen compound metabolic process; ","GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0042470 melanosome; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0048770 pigment granule; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0042587 glycogen granule; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0005794 Golgi apparatus; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016417 S-acyltransferase activity; GO:1901265 nucleoside phosphate binding; GO:0004319 enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity; GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; GO:0046983 protein dimerization activity; GO:0070402 NADPH binding; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0047117 enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity; GO:0016835 carbon-oxygen lyase activity; GO:0102132 3-oxo-pimeloyl-[acp] methyl ester reductase activity; GO:0016297 acyl-[acyl-carrier-protein] hydrolase activity; GO:0016614 oxidoreductase activity, acting on CH-OH group of donors; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; GO:0016746 transferase activity, transferring acyl groups; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0045296 cadherin binding; GO:0016418 S-acetyltransferase activity; GO:0043168 anion binding; GO:0016740 transferase activity; GO:0004312 fatty acid synthase activity; GO:0016419 S-malonyltransferase activity; GO:0004320 oleoyl-[acyl-carrier-protein] hydrolase activity; GO:0003723 RNA binding; GO:0031177 phosphopantetheine binding; GO:0004313 [acyl-carrier-protein] S-acetyltransferase activity; GO:0019842 vitamin binding; GO:0016420 malonyltransferase activity; GO:0016296 palmitoyl-[acyl-carrier-protein] hydrolase activity; GO:0047451 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity; GO:0043167 ion binding; GO:0004316 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity; GO:0016829 lyase activity; GO:0016836 hydro-lyase activity; GO:0008144 drug binding; GO:0033218 amide binding; GO:0000166 nucleotide binding; GO:0016790 thiolester hydrolase activity; GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity; GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups; GO:0048037 cofactor binding; GO:0019171 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity; GO:0016407 acetyltransferase activity; GO:0016491 oxidoreductase activity; GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors; GO:0004317 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity; GO:0050839 cell adhesion molecule binding; GO:0072341 modified amino acid binding; GO:0004314 [acyl-carrier-protein] S-malonyltransferase activity; GO:0042803 protein homodimerization activity; GO:0003676 nucleic acid binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0016295 myristoyl-[acyl-carrier-protein] hydrolase activity; GO:0050661 NADP binding; GO:0050662 coenzyme binding; GO:0036094 small molecule binding; ","K00665","FASN; fatty acid synthase, animal type [EC:2.3.1.85]","hsa00061 Fatty acid biosynthesis - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa01212 Fatty acid metabolism - Homo sapiens (human); hsa04910 Insulin signaling pathway - Homo sapiens (human); hsa04152 AMPK signaling pathway - Homo sapiens (human); ","IPR016035; IPR020807; IPR013149; IPR020841; IPR011032; IPR020843; IPR013217; IPR013968; IPR016036; IPR032821; IPR029058; IPR014031; IPR029063; IPR014043; IPR014030; IPR020801; IPR016039; IPR020806; IPR023102; IPR001031; IPR009081; IPR016040; IPR001227; ","\"Acyl transferase/acyl hydrolase/lysophospholipase; Polyketide synthase, dehydratase domain; Alcohol dehydrogenase, C-terminal; Polyketide synthase, beta-ketoacyl synthase domain; GroES-like; Polyketide synthase, enoylreductase domain; Methyltransferase type 12; Polyketide synthase, ketoreductase domain; Malonyl-CoA ACP transacylase, ACP-binding; Ketoacyl-synthetase, C-terminal extension; Alpha/Beta hydrolase fold; Beta-ketoacyl synthase, C-terminal; S-adenosyl-L-methionine-dependent methyltransferase; Acyl transferase; Beta-ketoacyl synthase, N-terminal; Polyketide synthase, acyl transferase domain; Thiolase-like; Polyketide synthase, phosphopantetheine-binding domain; Fatty acid synthase, domain 2; Thioesterase; Phosphopantetheine binding ACP domain; NAD(P)-binding domain; Acyl transferase domain; \"\r"]
["P49406","39S ribosomal protein L19, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL19","MRPL19",33.535,4.6247,6.5,2,2,2,0.903,0.994,1.036,1.13,0.986,0.96,1.049,0.512,"mitochondria\r","GO:0016043 cellular component organization; GO:0006518 peptide metabolic process; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:0043241 protein complex disassembly; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0043624 cellular protein complex disassembly; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006412 translation; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0071822 protein complex subunit organization; GO:0006414 translational elongation; GO:0043043 peptide biosynthetic process; GO:0044763 single-organism cellular process; GO:0032984 macromolecular complex disassembly; GO:0006807 nitrogen compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0032543 mitochondrial translation; GO:0070126 mitochondrial translational termination; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0006415 translational termination; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0070125 mitochondrial translational elongation; GO:0044260 cellular macromolecule metabolic process; GO:0022411 cellular component disassembly; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0071840 cellular component organization or biogenesis; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005762 mitochondrial large ribosomal subunit; GO:0005623 cell; GO:0000313 organellar ribosome; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:0031965 nuclear membrane; GO:0070013 intracellular organelle lumen; GO:0044391 ribosomal subunit; GO:0005622 intracellular; GO:0044464 cell part; GO:0019866 organelle inner membrane; GO:0000315 organellar large ribosomal subunit; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005840 ribosome; GO:0005759 mitochondrial matrix; GO:0044429 mitochondrial part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005635 nuclear envelope; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005761 mitochondrial ribosome; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0015934 large ribosomal subunit; GO:0031975 envelope; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0003735 structural constituent of ribosome; GO:0005198 structural molecule activity; ","K02884","RP-L19; large subunit ribosomal protein L19","hsa03010 Ribosome - Homo sapiens (human); ","IPR008991; ","Translation protein SH3-like domain; \r"]
["P49411","Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM","TUFM",49.541,225.44,48.7,19,41,19,1.038,1.033,1.048,0.951,0.968,0.972,0.927,0.000662,"mitochondria\r","GO:0006518 peptide metabolic process; GO:0045471 response to ethanol; GO:1901700 response to oxygen-containing compound; GO:0044267 cellular protein metabolic process; GO:0009058 biosynthetic process; GO:0050896 response to stimulus; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006412 translation; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006414 translational elongation; GO:0043043 peptide biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0097305 response to alcohol; GO:0043603 cellular amide metabolic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0042221 response to chemical; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005740 mitochondrial envelope; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0043209 myelin sheath; GO:0005622 intracellular; GO:0044464 cell part; GO:0019866 organelle inner membrane; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0043233 organelle lumen; GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0042645 mitochondrial nucleoid; GO:0043232 intracellular non-membrane-bounded organelle; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031975 envelope; GO:0031966 mitochondrial membrane; GO:0009295 nucleoid; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0003746 translation elongation factor activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0003924 GTPase activity; GO:0043168 anion binding; GO:0019001 guanyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003723 RNA binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0008135 translation factor activity, RNA binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003676 nucleic acid binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0032561 guanyl ribonucleotide binding; GO:0036094 small molecule binding; ","K02358",null,null,"IPR004160; IPR004161; IPR009001; IPR027417; IPR000795; IPR033720; IPR009000; ","\"Translation elongation factor EFTu/EF1A, C-terminal; Translation elongation factor EFTu-like, domain 2; Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal; P-loop containing nucleoside triphosphate hydrolase; Transcription factor, GTP-binding domain; Elongation factor Tu, domain 2; Translation protein, beta-barrel domain; \"\r"]
["P49454","Centromere protein F OS=Homo sapiens OX=9606 GN=CENPF","CENPF",367.76,2.3656,0.4,2,3,2,1.028,0.94,1.102,1.028,1.021,0.891,0.958,0.545,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0007420 brain development; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:1902100 negative regulation of metaphase/anaphase transition of cell cycle; GO:0015031 protein transport; GO:0033048 negative regulation of mitotic sister chromatid segregation; GO:0008152 metabolic process; GO:0031577 spindle checkpoint; GO:0065003 macromolecular complex assembly; GO:0051784 negative regulation of nuclear division; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0043170 macromolecule metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0008104 protein localization; GO:0007399 nervous system development; GO:0000278 mitotic cell cycle; GO:0018130 heterocycle biosynthetic process; GO:0007059 chromosome segregation; GO:1905818 regulation of chromosome separation; GO:0080090 regulation of primary metabolic process; GO:0007088 regulation of mitotic nuclear division; GO:0034508 centromere complex assembly; GO:0044763 single-organism cellular process; GO:0051985 negative regulation of chromosome segregation; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0065004 protein-DNA complex assembly; GO:0006810 transport; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0010948 negative regulation of cell cycle process; GO:1905819 negative regulation of chromosome separation; GO:0007417 central nervous system development; GO:0044260 cellular macromolecule metabolic process; GO:0051301 cell division; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0051383 kinetochore organization; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0051640 organelle localization; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0007346 regulation of mitotic cell cycle; GO:0006259 DNA metabolic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0051239 regulation of multicellular organismal process; GO:0045892 negative regulation of transcription, DNA-templated; GO:0042493 response to drug; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:1901987 regulation of cell cycle phase transition; GO:0021591 ventricular system development; GO:0009889 regulation of biosynthetic process; GO:0007093 mitotic cell cycle checkpoint; GO:0061061 muscle structure development; GO:0051171 regulation of nitrogen compound metabolic process; GO:0010389 regulation of G2/M transition of mitotic cell cycle; GO:0007275 multicellular organism development; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0006461 protein complex assembly; GO:0001822 kidney development; GO:0071173 spindle assembly checkpoint; GO:0048731 system development; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0008283 cell proliferation; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0051656 establishment of organelle localization; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0033044 regulation of chromosome organization; GO:0045184 establishment of protein localization; GO:0033046 negative regulation of sister chromatid segregation; GO:0009890 negative regulation of biosynthetic process; GO:2001251 negative regulation of chromosome organization; GO:0051276 chromosome organization; GO:0010965 regulation of mitotic sister chromatid separation; GO:0098813 nuclear chromosome segregation; GO:0006996 organelle organization; GO:0000280 nuclear division; GO:0007062 sister chromatid cohesion; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0048634 regulation of muscle organ development; GO:0007067 mitotic nuclear division; GO:0048869 cellular developmental process; GO:0051129 negative regulation of cellular component organization; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0051253 negative regulation of RNA metabolic process; GO:0030071 regulation of mitotic metaphase/anaphase transition; GO:0051234 establishment of localization; GO:2001141 regulation of RNA biosynthetic process; GO:0000819 sister chromatid segregation; GO:0050000 chromosome localization; GO:0051783 regulation of nuclear division; GO:0045930 negative regulation of mitotic cell cycle; GO:0051649 establishment of localization in cell; GO:0022607 cellular component assembly; GO:1901991 negative regulation of mitotic cell cycle phase transition; GO:0000075 cell cycle checkpoint; GO:0060322 head development; GO:0033036 macromolecule localization; GO:0051726 regulation of cell cycle; GO:0071824 protein-DNA complex subunit organization; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0033045 regulation of sister chromatid segregation; GO:0071822 protein complex subunit organization; GO:0031326 regulation of cellular biosynthetic process; GO:0007094 mitotic spindle assembly checkpoint; GO:0033047 regulation of mitotic sister chromatid segregation; GO:1901360 organic cyclic compound metabolic process; GO:0045841 negative regulation of mitotic metaphase/anaphase transition; GO:0010605 negative regulation of macromolecule metabolic process; GO:1902589 single-organism organelle organization; GO:0010639 negative regulation of organelle organization; GO:0016202 regulation of striated muscle tissue development; GO:0001655 urogenital system development; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0090304 nucleic acid metabolic process; GO:0007517 muscle organ development; GO:1902679 negative regulation of RNA biosynthetic process; GO:0019222 regulation of metabolic process; GO:0070271 protein complex biogenesis; GO:0045839 negative regulation of mitotic nuclear division; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0016043 cellular component organization; GO:0045786 negative regulation of cell cycle; GO:0006725 cellular aromatic compound metabolic process; GO:1901988 negative regulation of cell cycle phase transition; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0048285 organelle fission; GO:0072001 renal system development; GO:0031324 negative regulation of cellular metabolic process; GO:0051310 metaphase plate congression; GO:0050896 response to stimulus; GO:2000816 negative regulation of mitotic sister chromatid separation; GO:0071704 organic substance metabolic process; GO:0071174 mitotic spindle checkpoint; GO:0030154 cell differentiation; GO:0070925 organelle assembly; GO:0071897 DNA biosynthetic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0043623 cellular protein complex assembly; GO:0034622 cellular macromolecular complex assembly; GO:0051983 regulation of chromosome segregation; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0051303 establishment of chromosome localization; GO:1901861 regulation of muscle tissue development; GO:0033043 regulation of organelle organization; GO:1902099 regulation of metaphase/anaphase transition of cell cycle; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:1902749 regulation of cell cycle G2/M phase transition; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0051382 kinetochore assembly; GO:0043933 macromolecular complex subunit organization; GO:0051641 cellular localization; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044767 single-organism developmental process; GO:0051128 regulation of cellular component organization; GO:0031327 negative regulation of cellular biosynthetic process; GO:0022402 cell cycle process; GO:0007049 cell cycle; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0000940 condensed chromosome outer kinetochore; GO:0044422 organelle part; GO:0000777 condensed chromosome kinetochore; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0000793 condensed chromosome; GO:0005815 microtubule organizing center; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0044441 ciliary part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0048471 perinuclear region of cytoplasm; GO:0043227 membrane-bounded organelle; GO:0000776 kinetochore; GO:0005930 axoneme; GO:0097539 ciliary transition fiber; GO:0043233 organelle lumen; GO:0045120 pronucleus; GO:0005929 cilium; GO:0043229 intracellular organelle; GO:0000922 spindle pole; GO:0042995 cell projection; GO:0005635 nuclear envelope; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0000779 condensed chromosome, centromeric region; GO:0031967 organelle envelope; GO:0097014 ciliary plasm; GO:0044446 intracellular organelle part; GO:0030496 midbody; GO:0036064 ciliary basal body; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0005819 spindle; GO:0098687 chromosomal region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005813 centrosome; GO:0016363 nuclear matrix; GO:0031975 envelope; GO:0000775 chromosome, centromeric region; GO:0034399 nuclear periphery; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0070840 dynein complex binding; GO:0042802 identical protein binding; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0046983 protein dimerization activity; GO:0044877 macromolecular complex binding; GO:0005515 protein binding; GO:0008022 protein C-terminus binding; GO:0003682 chromatin binding; GO:0008134 transcription factor binding; GO:0032403 protein complex binding; ","K11499",null,null,"IPR018463; IPR019513; IPR018302; ","\"Centromere protein Cenp-F, N-terminal; Centromere protein Cenp-F, leucine-rich repeat-containing domain; Kinetochore protein Cenp-F/LEK1, Rb protein-binding domain; \"\r"]
["P49588","Alanine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=AARS","AARS",106.81,98.249,24.2,19,26,19,1.017,0.995,1.039,0.967,0.992,1.001,0.97,0.136,"cytoplasm\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0010941 regulation of cell death; GO:0006518 peptide metabolic process; GO:0007420 brain development; GO:0010608 posttranscriptional regulation of gene expression; GO:0043523 regulation of neuron apoptotic process; GO:0009451 RNA modification; GO:0044237 cellular metabolic process; GO:0050877 neurological system process; GO:0008152 metabolic process; GO:0035966 response to topologically incorrect protein; GO:0008544 epidermis development; GO:0009719 response to endogenous stimulus; GO:0006418 tRNA aminoacylation for protein translation; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0007399 nervous system development; GO:0006396 RNA processing; GO:0051716 cellular response to stimulus; GO:0043588 skin development; GO:0080090 regulation of primary metabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0021549 cerebellum development; GO:0098773 skin epidermis development; GO:0048513 animal organ development; GO:0010243 response to organonitrogen compound; GO:0007417 central nervous system development; GO:0044710 single-organism metabolic process; GO:0008033 tRNA processing; GO:1901698 response to nitrogen compound; GO:0044260 cellular macromolecule metabolic process; GO:0021695 cerebellar cortex development; GO:0060548 negative regulation of cell death; GO:0001942 hair follicle development; GO:0043436 oxoacid metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0033554 cellular response to stress; GO:0034976 response to endoplasmic reticulum stress; GO:0042303 molting cycle; GO:1901700 response to oxygen-containing compound; GO:0044267 cellular protein metabolic process; GO:0043067 regulation of programmed cell death; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0046483 heterocycle metabolic process; GO:0043524 negative regulation of neuron apoptotic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0050885 neuromuscular process controlling balance; GO:0030902 hindbrain development; GO:1901215 negative regulation of neuron death; GO:0006986 response to unfolded protein; GO:0006950 response to stress; GO:0006450 regulation of translational fidelity; GO:0048731 system development; GO:0022405 hair cycle process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0042633 hair cycle; GO:1901576 organic substance biosynthetic process; GO:0034248 regulation of cellular amide metabolic process; GO:0043038 amino acid activation; GO:0043412 macromolecule modification; GO:0050905 neuromuscular process; GO:1901564 organonitrogen compound metabolic process; GO:0001101 response to acid chemical; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0030968 endoplasmic reticulum unfolded protein response; GO:0006457 protein folding; GO:0007165 signal transduction; GO:0006520 cellular amino acid metabolic process; GO:0022404 molting cycle process; GO:0007154 cell communication; GO:0060322 head development; GO:0006412 translation; GO:0070887 cellular response to chemical stimulus; GO:0034470 ncRNA processing; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0043200 response to amino acid; GO:0010468 regulation of gene expression; GO:0009888 tissue development; GO:0031326 regulation of cellular biosynthetic process; GO:0043043 peptide biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0023052 signaling; GO:0016070 RNA metabolic process; GO:0021680 cerebellar Purkinje cell layer development; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0090304 nucleic acid metabolic process; GO:0019222 regulation of metabolic process; GO:0022037 metencephalon development; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:0043069 negative regulation of programmed cell death; GO:0035967 cellular response to topologically incorrect protein; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0050896 response to stimulus; GO:0043039 tRNA aminoacylation; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0043066 negative regulation of apoptotic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0006400 tRNA modification; GO:0009987 cellular process; GO:0006419 alanyl-tRNA aminoacylation; GO:1901214 regulation of neuron death; GO:0003008 system process; GO:0034620 cellular response to unfolded protein; GO:0006448 regulation of translational elongation; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0006399 tRNA metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044767 single-organism developmental process; GO:0006417 regulation of translation; GO:0051246 regulation of protein metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0034660 ncRNA metabolic process; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds; GO:0016597 amino acid binding; GO:1901265 nucleoside phosphate binding; GO:0052689 carboxylic ester hydrolase activity; GO:0016875 ligase activity, forming carbon-oxygen bonds; GO:0016874 ligase activity; GO:0016787 hydrolase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0031406 carboxylic acid binding; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0000049 tRNA binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0004812 aminoacyl-tRNA ligase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0004813 alanine-tRNA ligase activity; GO:0003723 RNA binding; GO:0002161 aminoacyl-tRNA editing activity; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0043177 organic acid binding; GO:0000166 nucleotide binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003676 nucleic acid binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0046872 metal ion binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; ","K01872","AARS; alanyl-tRNA synthetase [EC:6.1.1.7]","hsa00970 Aminoacyl-tRNA biosynthesis - Homo sapiens (human); ","IPR018163; IPR018164; IPR012947; IPR018162; IPR003156; IPR009000; IPR018165; ","\"Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain; Alanyl-tRNA synthetase, class IIc, N-terminal; Threonyl/alanyl tRNA synthetase, SAD; Alanine-tRNA ligase, class IIc, anti-codon-binding domain; DHHA1 domain; Translation protein, beta-barrel domain; Alanyl-tRNA synthetase, class IIc, core domain; \"\r"]
["P49591","Serine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=SARS","SARS",58.777,56.305,26.5,13,22,13,0.963,0.907,0.942,1.034,1.052,1.068,1.122,0.0044,"cytoplasm\r","GO:0006518 peptide metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0043039 tRNA aminoacylation; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0006418 tRNA aminoacylation for protein translation; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0006412 translation; GO:0009987 cellular process; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0018130 heterocycle biosynthetic process; GO:0006434 seryl-tRNA aminoacylation; GO:0043043 peptide biosynthetic process; GO:0016259 selenocysteine metabolic process; GO:0044281 small molecule metabolic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0043603 cellular amide metabolic process; GO:1901605 alpha-amino acid metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0016070 RNA metabolic process; GO:0006399 tRNA metabolic process; GO:0090304 nucleic acid metabolic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0009069 serine family amino acid metabolic process; GO:0044710 single-organism metabolic process; GO:0008033 tRNA processing; GO:0043038 amino acid activation; GO:0044260 cellular macromolecule metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0097056 selenocysteinyl-tRNA(Sec) biosynthetic process; GO:0006082 organic acid metabolic process; GO:0034660 ncRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0043436 oxoacid metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds; GO:0003723 RNA binding; GO:0004828 serine-tRNA ligase activity; GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0016875 ligase activity, forming carbon-oxygen bonds; GO:0016874 ligase activity; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0098619 selenocysteine-tRNA ligase activity; GO:0000166 nucleotide binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0004812 aminoacyl-tRNA ligase activity; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K01875","SARS; seryl-tRNA synthetase [EC:6.1.1.11]","hsa00970 Aminoacyl-tRNA biosynthesis - Homo sapiens (human); ","IPR010978; IPR002314; IPR015866; IPR033729; IPR006195; ","\"tRNA-binding arm; Aminoacyl-tRNA synthetase, class II (G/ P/ S/T); Serine-tRNA synthetase, type1, N-terminal; Serine-tRNA ligase catalytic core domain; Aminoacyl-tRNA synthetase, class II; \"\r"]
["P49593","Protein phosphatase 1F OS=Homo sapiens OX=9606 GN=PPM1F","PPM1F",49.83,25.331,17.8,6,6,6,1.013,1.046,0.933,0.996,1.063,0.96,1.009,0.848,"cytoplasm\r","GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0030335 positive regulation of cell migration; GO:0032270 positive regulation of cellular protein metabolic process; GO:0044237 cellular metabolic process; GO:0045927 positive regulation of growth; GO:0008152 metabolic process; GO:0051894 positive regulation of focal adhesion assembly; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0050921 positive regulation of chemotaxis; GO:0051493 regulation of cytoskeleton organization; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation; GO:0052548 regulation of endopeptidase activity; GO:0001954 positive regulation of cell-matrix adhesion; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0051174 regulation of phosphorus metabolic process; GO:0010950 positive regulation of endopeptidase activity; GO:0010632 regulation of epithelial cell migration; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0051272 positive regulation of cellular component movement; GO:0043086 negative regulation of catalytic activity; GO:1901888 regulation of cell junction assembly; GO:0031323 regulation of cellular metabolic process; GO:0010811 positive regulation of cell-substrate adhesion; GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0051336 regulation of hydrolase activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:1902905 positive regulation of supramolecular fiber organization; GO:0006464 cellular protein modification process; GO:0032233 positive regulation of actin filament bundle assembly; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0010952 positive regulation of peptidase activity; GO:0043068 positive regulation of programmed cell death; GO:1902903 regulation of supramolecular fiber organization; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0001952 regulation of cell-matrix adhesion; GO:0097190 apoptotic signaling pathway; GO:2001056 positive regulation of cysteine-type endopeptidase activity; GO:0032956 regulation of actin cytoskeleton organization; GO:0031399 regulation of protein modification process; GO:0016570 histone modification; GO:0043067 regulation of programmed cell death; GO:0044267 cellular protein metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:2000147 positive regulation of cell motility; GO:0051239 regulation of multicellular organismal process; GO:0045892 negative regulation of transcription, DNA-templated; GO:0042493 response to drug; GO:0051345 positive regulation of hydrolase activity; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:2000145 regulation of cell motility; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0001933 negative regulation of protein phosphorylation; GO:0016569 covalent chromatin modification; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0016576 histone dephosphorylation; GO:0051495 positive regulation of cytoskeleton organization; GO:0045785 positive regulation of cell adhesion; GO:0051270 regulation of cellular component movement; GO:0032231 regulation of actin filament bundle assembly; GO:0033135 regulation of peptidyl-serine phosphorylation; GO:0032101 regulation of response to external stimulus; GO:0032970 regulation of actin filament-based process; GO:0030334 regulation of cell migration; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0030155 regulation of cell adhesion; GO:0051492 regulation of stress fiber assembly; GO:0009890 negative regulation of biosynthetic process; GO:0051247 positive regulation of protein metabolic process; GO:0051276 chromosome organization; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0051496 positive regulation of stress fiber assembly; GO:0012501 programmed cell death; GO:0048584 positive regulation of response to stimulus; GO:0043412 macromolecule modification; GO:0010810 regulation of cell-substrate adhesion; GO:0045936 negative regulation of phosphate metabolic process; GO:1903391 regulation of adherens junction organization; GO:0040017 positive regulation of locomotion; GO:0090109 regulation of cell-substrate junction assembly; GO:0044699 single-organism process; GO:0051253 negative regulation of RNA metabolic process; GO:0031400 negative regulation of protein modification process; GO:0006796 phosphate-containing compound metabolic process; GO:0051130 positive regulation of cellular component organization; GO:0033137 negative regulation of peptidyl-serine phosphorylation; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0033673 negative regulation of kinase activity; GO:0032103 positive regulation of response to external stimulus; GO:0006915 apoptotic process; GO:0070887 cellular response to chemical stimulus; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:2000116 regulation of cysteine-type endopeptidase activity; GO:0048522 positive regulation of cellular process; GO:1901890 positive regulation of cell junction assembly; GO:0051348 negative regulation of transferase activity; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0010942 positive regulation of cell death; GO:1903393 positive regulation of adherens junction organization; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0010638 positive regulation of organelle organization; GO:1902679 negative regulation of RNA biosynthetic process; GO:0006469 negative regulation of protein kinase activity; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0006325 chromatin organization; GO:0036211 protein modification process; GO:0052547 regulation of peptidase activity; GO:0043549 regulation of kinase activity; GO:0045859 regulation of protein kinase activity; GO:0016043 cellular component organization; GO:0035690 cellular response to drug; GO:0040008 regulation of growth; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0051893 regulation of focal adhesion assembly; GO:0043065 positive regulation of apoptotic process; GO:0044087 regulation of cellular component biogenesis; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0097193 intrinsic apoptotic signaling pathway; GO:0071704 organic substance metabolic process; GO:0045862 positive regulation of proteolysis; GO:0042326 negative regulation of phosphorylation; GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0009987 cellular process; GO:0006355 regulation of transcription, DNA-templated; GO:0035556 intracellular signal transduction; GO:0010629 negative regulation of gene expression; GO:0001932 regulation of protein phosphorylation; GO:0033043 regulation of organelle organization; GO:0010634 positive regulation of epithelial cell migration; GO:0035970 peptidyl-threonine dephosphorylation; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0050920 regulation of chemotaxis; GO:0006470 protein dephosphorylation; GO:0048518 positive regulation of biological process; GO:0016311 dephosphorylation; GO:0051252 regulation of RNA metabolic process; GO:0043085 positive regulation of catalytic activity; GO:0008219 cell death; GO:0051246 regulation of protein metabolic process; GO:0010563 negative regulation of phosphorus metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0051128 regulation of cellular component organization; GO:0031327 negative regulation of cellular biosynthetic process; GO:0040012 regulation of locomotion; GO:0044089 positive regulation of cellular component biogenesis; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0048471 perinuclear region of cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0043234 protein complex; GO:0005829 cytosol; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:0003824 catalytic activity; GO:0042578 phosphoric ester hydrolase activity; GO:0005488 binding; GO:0004722 protein serine/threonine phosphatase activity; GO:0016791 phosphatase activity; GO:0043167 ion binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0004721 phosphoprotein phosphatase activity; GO:0004723 calcium-dependent protein serine/threonine phosphatase activity; GO:0033192 calmodulin-dependent protein phosphatase activity; ","K17502",null,null,"IPR001932; ","PPM-type phosphatase domain; \r"]
["P49720","Proteasome subunit beta type-3 OS=Homo sapiens OX=9606 GN=PSMB3","PSMB3",22.949,37.626,33.2,7,10,7,0.992,0.991,0.907,1.04,1.043,1.086,1.097,0.0474,"cytoplasm\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0002220 innate immune response activating cell surface receptor signaling pathway; GO:0007166 cell surface receptor signaling pathway; GO:0010608 posttranscriptional regulation of gene expression; GO:0051443 positive regulation of ubiquitin-protein transferase activity; GO:0031347 regulation of defense response; GO:0071345 cellular response to cytokine stimulus; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:1903364 positive regulation of cellular protein catabolic process; GO:0008152 metabolic process; GO:0044093 positive regulation of molecular function; GO:0090263 positive regulation of canonical Wnt signaling pathway; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0051347 positive regulation of transferase activity; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0016055 Wnt signaling pathway; GO:0044419 interspecies interaction between organisms; GO:1903362 regulation of cellular protein catabolic process; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0006521 regulation of cellular amino acid metabolic process; GO:0002758 innate immune response-activating signal transduction; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0010972 negative regulation of G2/M transition of mitotic cell cycle; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0060828 regulation of canonical Wnt signaling pathway; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0033209 tumor necrosis factor-mediated signaling pathway; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0000165 MAPK cascade; GO:1903506 regulation of nucleic acid-templated transcription; GO:2000058 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0019884 antigen processing and presentation of exogenous antigen; GO:1901575 organic substance catabolic process; GO:0010948 negative regulation of cell cycle process; GO:0007267 cell-cell signaling; GO:0002223 stimulatory C-type lectin receptor signaling pathway; GO:0032269 negative regulation of cellular protein metabolic process; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0030163 protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0060071 Wnt signaling pathway, planar cell polarity pathway; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:0002682 regulation of immune system process; GO:0006464 cellular protein modification process; GO:0031145 anaphase-promoting complex-dependent catabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016310 phosphorylation; GO:0033554 cellular response to stress; GO:0007346 regulation of mitotic cell cycle; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0051239 regulation of multicellular organismal process; GO:0043487 regulation of RNA stability; GO:0000209 protein polyubiquitination; GO:0031349 positive regulation of defense response; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0009889 regulation of biosynthetic process; GO:1901987 regulation of cell cycle phase transition; GO:0009896 positive regulation of catabolic process; GO:0043620 regulation of DNA-templated transcription in response to stress; GO:0070482 response to oxygen levels; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0044248 cellular catabolic process; GO:0010389 regulation of G2/M transition of mitotic cell cycle; GO:0042176 regulation of protein catabolic process; GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; GO:0038093 Fc receptor signaling pathway; GO:0050778 positive regulation of immune response; GO:0009966 regulation of signal transduction; GO:0023014 signal transduction by protein phosphorylation; GO:0071456 cellular response to hypoxia; GO:0038061 NIK/NF-kappaB signaling; GO:0002253 activation of immune response; GO:0006950 response to stress; GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; GO:0016567 protein ubiquitination; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress; GO:1904666 regulation of ubiquitin protein ligase activity; GO:1903321 negative regulation of protein modification by small protein conjugation or removal; GO:0055085 transmembrane transport; GO:0051247 positive regulation of protein metabolic process; GO:0051438 regulation of ubiquitin-protein transferase activity; GO:0031398 positive regulation of protein ubiquitination; GO:0032446 protein modification by small protein conjugation; GO:0006793 phosphorus metabolic process; GO:0030111 regulation of Wnt signaling pathway; GO:0031325 positive regulation of cellular metabolic process; GO:0030177 positive regulation of Wnt signaling pathway; GO:1904668 positive regulation of ubiquitin protein ligase activity; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0036293 response to decreased oxygen levels; GO:0051179 localization; GO:0043412 macromolecule modification; GO:0048584 positive regulation of response to stimulus; GO:0050793 regulation of developmental process; GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process; GO:0051444 negative regulation of ubiquitin-protein transferase activity; GO:0070646 protein modification by small protein removal; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0031331 positive regulation of cellular catabolic process; GO:0090090 negative regulation of canonical Wnt signaling pathway; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0031400 negative regulation of protein modification process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0035567 non-canonical Wnt signaling pathway; GO:0031396 regulation of protein ubiquitination; GO:1905330 regulation of morphogenesis of an epithelium; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0045930 negative regulation of mitotic cell cycle; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0045088 regulation of innate immune response; GO:1901991 negative regulation of mitotic cell cycle phase transition; GO:0009893 positive regulation of metabolic process; GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0034612 response to tumor necrosis factor; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0051726 regulation of cell cycle; GO:0070887 cellular response to chemical stimulus; GO:0050851 antigen receptor-mediated signaling pathway; GO:0010468 regulation of gene expression; GO:0030178 negative regulation of Wnt signaling pathway; GO:0034097 response to cytokine; GO:0031326 regulation of cellular biosynthetic process; GO:0048002 antigen processing and presentation of peptide antigen; GO:0048522 positive regulation of cellular process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0051348 negative regulation of transferase activity; GO:0070647 protein modification by small protein conjugation or removal; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0198738 cell-cell signaling by wnt; GO:0010565 regulation of cellular ketone metabolic process; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0036211 protein modification process; GO:2000026 regulation of multicellular organismal development; GO:0090175 regulation of establishment of planar polarity; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0045786 negative regulation of cell cycle; GO:1904667 negative regulation of ubiquitin protein ligase activity; GO:0002218 activation of innate immune response; GO:0044257 cellular protein catabolic process; GO:0071356 cellular response to tumor necrosis factor; GO:1901988 negative regulation of cell cycle phase transition; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0016579 protein deubiquitination; GO:0050896 response to stimulus; GO:0010498 proteasomal protein catabolic process; GO:0071704 organic substance metabolic process; GO:1903322 positive regulation of protein modification by small protein conjugation or removal; GO:0045862 positive regulation of proteolysis; GO:2000027 regulation of organ morphogenesis; GO:0006468 protein phosphorylation; GO:0023056 positive regulation of signaling; GO:0016032 viral process; GO:0001666 response to hypoxia; GO:0002757 immune response-activating signal transduction; GO:0006508 proteolysis; GO:0010647 positive regulation of cell communication; GO:0071453 cellular response to oxygen levels; GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:0019221 cytokine-mediated signaling pathway; GO:0009987 cellular process; GO:0033238 regulation of cellular amine metabolic process; GO:0031397 negative regulation of protein ubiquitination; GO:0043632 modification-dependent macromolecule catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0045089 positive regulation of innate immune response; GO:0006355 regulation of transcription, DNA-templated; GO:0035556 intracellular signal transduction; GO:0019941 modification-dependent protein catabolic process; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition; GO:0031401 positive regulation of protein modification process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia; GO:1902749 regulation of cell cycle G2/M phase transition; GO:0043488 regulation of mRNA stability; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0019882 antigen processing and presentation; GO:0050852 T cell receptor signaling pathway; GO:0051246 regulation of protein metabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0002684 positive regulation of immune system process; GO:0009057 macromolecule catabolic process; GO:0038095 Fc-epsilon receptor signaling pathway; GO:0051248 negative regulation of protein metabolic process; GO:0022402 cell cycle process; GO:0045732 positive regulation of protein catabolic process; GO:0009967 positive regulation of signal transduction; GO:1902750 negative regulation of cell cycle G2/M phase transition; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0036294 cellular response to decreased oxygen levels; GO:0065007 biological regulation; ","GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0019774 proteasome core complex, beta-subunit complex; GO:0044422 organelle part; GO:1905369 endopeptidase complex; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:1905368 peptidase complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0000502 proteasome complex; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005839 proteasome core complex; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0004175 endopeptidase activity; GO:0004298 threonine-type endopeptidase activity; GO:0008233 peptidase activity; GO:0070003 threonine-type peptidase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0016787 hydrolase activity; GO:0005515 protein binding; ","K02735","PSMB3; 20S proteasome subunit beta 3 [EC:3.4.25.1]","hsa03050 Proteasome - Homo sapiens (human); ","IPR029055; ","\"Nucleophile aminohydrolases, N-terminal; \"\r"]
["P49746","Thrombospondin-3 OS=Homo sapiens OX=9606 GN=THBS3","THBS3",104.2,31.575,8.3,7,9,7,1.037,1.085,1.06,0.957,0.968,0.977,0.912,0.00306,"extracellular\r","GO:0044707 single-multicellular organism process; GO:0070977 bone maturation; GO:0021700 developmental maturation; GO:0051216 cartilage development; GO:0061430 bone trabecula morphogenesis; GO:0044699 single-organism process; GO:0098868 bone growth; GO:0048799 animal organ maturation; GO:0035265 organ growth; GO:0009653 anatomical structure morphogenesis; GO:0022610 biological adhesion; GO:0060349 bone morphogenesis; GO:0060343 trabecula formation; GO:0007160 cell-matrix adhesion; GO:0007155 cell adhesion; GO:0061448 connective tissue development; GO:0007275 multicellular organism development; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0032502 developmental process; GO:0009888 tissue development; GO:0043931 ossification involved in bone maturation; GO:0060350 endochondral bone morphogenesis; GO:0048731 system development; GO:0001503 ossification; GO:0060351 cartilage development involved in endochondral bone morphogenesis; GO:0060346 bone trabecula formation; GO:0061383 trabecula morphogenesis; GO:0032501 multicellular organismal process; GO:0048705 skeletal system morphogenesis; GO:0060348 bone development; GO:0048513 animal organ development; GO:0031589 cell-substrate adhesion; GO:0003416 endochondral bone growth; GO:0044767 single-organism developmental process; GO:0009887 animal organ morphogenesis; GO:0003417 growth plate cartilage development; GO:0048589 developmental growth; GO:0040007 growth; GO:0048856 anatomical structure development; GO:0001501 skeletal system development; GO:0071695 anatomical structure maturation; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0048471 perinuclear region of cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0044444 cytoplasmic part; ","GO:0097367 carbohydrate derivative binding; GO:0005488 binding; GO:0043167 ion binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0043168 anion binding; GO:0005509 calcium ion binding; GO:0008201 heparin binding; GO:0005539 glycosaminoglycan binding; GO:1901681 sulfur compound binding; ","K04659","THBS2S; thrombospondin 2/3/4/5","hsa05144 Malaria - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa04512 ECM-receptor interaction - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); ","IPR001881; IPR008859; IPR024665; IPR000742; IPR001791; IPR013320; ","\"EGF-like calcium-binding domain; Thrombospondin, C-terminal; Thrombospondin/cartilage oligomeric matrix protein, coiled-coil domain; EGF-like domain; Laminin G domain; Concanavalin A-like lectin/glucanase domain; \"\r"]
["P49754","Vacuolar protein sorting-associated protein 41 homolog OS=Homo sapiens OX=9606 GN=VPS41","VPS41",98.565,2.8415,1.8,2,2,2,1.172,0.938,1.006,0.944,1.014,0.938,0.929,0.379,"nucleus\r","GO:0060627 regulation of vesicle-mediated transport; GO:0072594 establishment of protein localization to organelle; GO:0044699 single-organism process; GO:0006623 protein targeting to vacuole; GO:0031338 regulation of vesicle fusion; GO:0006914 autophagy; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0072666 establishment of protein localization to vacuole; GO:0032879 regulation of localization; GO:0042144 vacuole fusion, non-autophagic; GO:0007033 vacuole organization; GO:0033365 protein localization to organelle; GO:0044801 single-organism membrane fusion; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0044763 single-organism cellular process; GO:0061025 membrane fusion; GO:0008333 endosome to lysosome transport; GO:0072665 protein localization to vacuole; GO:0006810 transport; GO:0016197 endosomal transport; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0043254 regulation of protein complex assembly; GO:0032940 secretion by cell; GO:0006906 vesicle fusion; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0090174 organelle membrane fusion; GO:0048193 Golgi vesicle transport; GO:0044087 regulation of cellular component biogenesis; GO:1902774 late endosome to lysosome transport; GO:1902578 single-organism localization; GO:0045324 late endosome to vacuole transport; GO:0006886 intracellular protein transport; GO:0044248 cellular catabolic process; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0034058 endosomal vesicle fusion; GO:0007041 lysosomal transport; GO:0051049 regulation of transport; GO:0016192 vesicle-mediated transport; GO:0044802 single-organism membrane organization; GO:0016050 vesicle organization; GO:0033043 regulation of organelle organization; GO:0071702 organic substance transport; GO:0048284 organelle fusion; GO:0035542 regulation of SNARE complex assembly; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0045055 regulated exocytosis; GO:0070727 cellular macromolecule localization; GO:0097576 vacuole fusion; GO:0007034 vacuolar transport; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0009056 catabolic process; GO:0006887 exocytosis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0030119 AP-type membrane coat adaptor complex; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0030123 AP-3 adaptor complex; GO:0005769 early endosome; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0005765 lysosomal membrane; GO:0015630 microtubule cytoskeleton; GO:0030136 clathrin-coated vesicle; GO:0031902 late endosome membrane; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0005764 lysosome; GO:0044431 Golgi apparatus part; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0033263 CORVET complex; GO:0099023 tethering complex; GO:0000323 lytic vacuole; GO:0010008 endosome membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0005770 late endosome; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0048475 coated membrane; GO:0044446 intracellular organelle part; GO:0044440 endosomal part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005798 Golgi-associated vesicle; GO:0030135 coated vesicle; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0030117 membrane coat; GO:0030897 HOPS complex; GO:0005794 Golgi apparatus; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0008092 cytoskeletal protein binding; GO:0042802 identical protein binding; GO:0046914 transition metal ion binding; GO:0043621 protein self-association; GO:0008017 microtubule binding; GO:0005488 binding; GO:0043167 ion binding; GO:0015631 tubulin binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0008270 zinc ion binding; GO:0051020 GTPase binding; GO:0019899 enzyme binding; ","K20184",null,null,"IPR001841; IPR011990; IPR013083; IPR017986; IPR015943; ","\"Zinc finger, RING-type; Tetratricopeptide-like helical domain; Zinc finger, RING/FYVE/PHD-type; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain; \"\r"]
["P49756","RNA-binding protein 25 OS=Homo sapiens OX=9606 GN=RBM25","RBM25",100.18,13.917,5.6,4,4,4,0.989,1.022,0.94,0.987,1.069,0.999,1.035,0.376,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0010941 regulation of cell death; GO:0000381 regulation of alternative mRNA splicing, via spliceosome; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0043067 regulation of programmed cell death; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0048024 regulation of mRNA splicing, via spliceosome; GO:0006396 RNA processing; GO:0010468 regulation of gene expression; GO:0080090 regulation of primary metabolic process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0050684 regulation of mRNA processing; GO:0044238 primary metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:0043484 regulation of RNA splicing; GO:1903311 regulation of mRNA metabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0010467 gene expression; GO:0016071 mRNA metabolic process; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005681 spliceosomal complex; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031974 membrane-enclosed lumen; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0005622 intracellular; GO:0044464 cell part; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003729 mRNA binding; GO:0003723 RNA binding; GO:1901265 nucleoside phosphate binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0036094 small molecule binding; ",{"$nulls":3},"IPR034268; IPR000504; IPR012677; IPR002483; ","\"RBM25, RNA recognition motif; RNA recognition motif domain; Nucleotide-binding alpha-beta plait domain; PWI domain; \"\r"]
["P49773","Histidine triad nucleotide-binding protein 1 OS=Homo sapiens OX=9606 GN=HINT1","HINT1",13.802,35.152,40.5,7,10,7,0.967,0.968,1.043,0.977,1.021,1.027,1.016,0.616,"cytoplasm\r","GO:0050850 positive regulation of calcium-mediated signaling; GO:0044700 single organism signaling; GO:0097659 nucleic acid-templated transcription; GO:0009117 nucleotide metabolic process; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:1901292 nucleoside phosphate catabolic process; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0006195 purine nucleotide catabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0006915 apoptotic process; GO:1901361 organic cyclic compound catabolic process; GO:0019693 ribose phosphate metabolic process; GO:0043170 macromolecule metabolic process; GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator; GO:0010468 regulation of gene expression; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0009166 nucleotide catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0072521 purine-containing compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0032774 RNA biosynthetic process; GO:0009154 purine ribonucleotide catabolic process; GO:0031323 regulation of cellular metabolic process; GO:0023052 signaling; GO:0016070 RNA metabolic process; GO:0019439 aromatic compound catabolic process; GO:1901575 organic substance catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0097190 apoptotic signaling pathway; GO:0006725 cellular aromatic compound metabolic process; GO:0046434 organophosphate catabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0009259 ribonucleotide metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0072523 purine-containing compound catabolic process; GO:0050896 response to stimulus; GO:0097193 intrinsic apoptotic signaling pathway; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0023056 positive regulation of signaling; GO:0009889 regulation of biosynthetic process; GO:0044248 cellular catabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0010647 positive regulation of cell communication; GO:0050848 regulation of calcium-mediated signaling; GO:0009059 macromolecule biosynthetic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0009966 regulation of signal transduction; GO:1902531 regulation of intracellular signal transduction; GO:0006355 regulation of transcription, DNA-templated; GO:0035556 intracellular signal transduction; GO:0044712 single-organism catabolic process; GO:0072331 signal transduction by p53 class mediator; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:1901136 carbohydrate derivative catabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009261 ribonucleotide catabolic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0006163 purine nucleotide metabolic process; GO:1901565 organonitrogen compound catabolic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0008219 cell death; GO:0019637 organophosphate metabolic process; GO:0010467 gene expression; GO:0009150 purine ribonucleotide metabolic process; GO:0009967 positive regulation of signal transduction; GO:0012501 programmed cell death; GO:0048584 positive regulation of response to stimulus; GO:0009056 catabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0000118 histone deacetylase complex; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:1901265 nucleoside phosphate binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0019901 protein kinase binding; GO:0005080 protein kinase C binding; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0019900 kinase binding; GO:0019899 enzyme binding; GO:0036094 small molecule binding; ","K02503",null,null,"IPR011146; ","HIT-like domain; \r"]
["P49821","NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV1","NDUFV1",50.817,59.621,26.3,10,12,10,1.002,1.053,1.113,0.908,1.013,1.012,0.926,0.177,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0006753 nucleoside phosphate metabolic process; GO:0007005 mitochondrion organization; GO:0019693 ribose phosphate metabolic process; GO:0071822 protein complex subunit organization; GO:0010257 NADH dehydrogenase complex assembly; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006119 oxidative phosphorylation; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0006120 mitochondrial electron transport, NADH to ubiquinone; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0097031 mitochondrial respiratory chain complex I biogenesis; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0022900 electron transport chain; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0070271 protein complex biogenesis; GO:0033108 mitochondrial respiratory chain complex assembly; GO:0016310 phosphorylation; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0042773 ATP synthesis coupled electron transport; GO:0009259 ribonucleotide metabolic process; GO:0022904 respiratory electron transport chain; GO:0071704 organic substance metabolic process; GO:0032981 mitochondrial respiratory chain complex I assembly; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009119 ribonucleoside metabolic process; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0043623 cellular protein complex assembly; GO:0046034 ATP metabolic process; GO:0034622 cellular macromolecular complex assembly; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0045333 cellular respiration; GO:0006163 purine nucleotide metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0046128 purine ribonucleoside metabolic process; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:0071840 cellular component organization or biogenesis; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0045271 respiratory chain complex I; GO:0044424 intracellular part; GO:0098798 mitochondrial protein complex; GO:0005747 mitochondrial respiratory chain complex I; GO:0005623 cell; GO:0044455 mitochondrial membrane part; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:1902494 catalytic complex; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0098803 respiratory chain complex; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005829 cytosol; GO:0005739 mitochondrion; GO:0005746 mitochondrial respiratory chain; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0030964 NADH dehydrogenase complex; GO:1990204 oxidoreductase complex; GO:0031975 envelope; GO:0043234 protein complex; GO:0031966 mitochondrial membrane; GO:0070469 respiratory chain; GO:0044444 cytoplasmic part; ","GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:1901265 nucleoside phosphate binding; GO:0043167 ion binding; GO:0050136 NADH dehydrogenase (quinone) activity; GO:0000166 nucleotide binding; GO:0051539 4 iron, 4 sulfur cluster binding; GO:0048037 cofactor binding; GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; GO:0008137 NADH dehydrogenase (ubiquinone) activity; GO:0016491 oxidoreductase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0097367 carbohydrate derivative binding; GO:0003954 NADH dehydrogenase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0051287 NAD binding; GO:0051536 iron-sulfur cluster binding; GO:0005488 binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0010181 FMN binding; GO:0036094 small molecule binding; GO:0050662 coenzyme binding; GO:0051540 metal cluster binding; ","K03942","NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:1.6.5.3 1.6.99.3]","hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); ","IPR011538; IPR019554; IPR019575; ","\"NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain; Soluble ligand binding domain; NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain; \"\r"]
["P49842","Serine/threonine-protein kinase 19 OS=Homo sapiens OX=9606 GN=STK19","STK19",40.915,2.6879,2.7,1,1,1,1.016,0.928,1.013,0.975,0.985,1.087,1.03,0.552,"nucleus\r","GO:0016310 phosphorylation; GO:0044267 cellular protein metabolic process; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0006468 protein phosphorylation; GO:0006793 phosphorus metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:0009987 cellular process; ","GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031974 membrane-enclosed lumen; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0004672 protein kinase activity; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016301 kinase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0004674 protein serine/threonine kinase activity; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0016740 transferase activity; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K08880"]
["P49862","Kallikrein-7 OS=Homo sapiens OX=9606 GN=KLK7","KLK7",27.524,35.887,19.4,5,8,5,0.719,0.814,0.718,1.276,1.233,1.184,1.641,4.55E-4,"extracellular\r","GO:0002702 positive regulation of production of molecular mediator of immune response; GO:0002786 regulation of antibacterial peptide production; GO:0016043 cellular component organization; GO:1900424 regulation of defense response to bacterium; GO:0002831 regulation of response to biotic stimulus; GO:0002922 positive regulation of humoral immune response; GO:1900426 positive regulation of defense response to bacterium; GO:0002759 regulation of antimicrobial humoral response; GO:0002920 regulation of humoral immune response; GO:0044699 single-organism process; GO:0080134 regulation of response to stress; GO:0031347 regulation of defense response; GO:0071704 organic substance metabolic process; GO:0002225 positive regulation of antimicrobial peptide production; GO:0008152 metabolic process; GO:0031349 positive regulation of defense response; GO:0043062 extracellular structure organization; GO:0032103 positive regulation of response to external stimulus; GO:0022617 extracellular matrix disassembly; GO:0008544 epidermis development; GO:0006508 proteolysis; GO:0043170 macromolecule metabolic process; GO:0030198 extracellular matrix organization; GO:0019538 protein metabolic process; GO:0002760 positive regulation of antimicrobial humoral response; GO:0002697 regulation of immune effector process; GO:0050778 positive regulation of immune response; GO:0009987 cellular process; GO:0032502 developmental process; GO:0043902 positive regulation of multi-organism process; GO:0009888 tissue development; GO:0043900 regulation of multi-organism process; GO:0002699 positive regulation of immune effector process; GO:0044763 single-organism cellular process; GO:0032101 regulation of response to external stimulus; GO:0002700 regulation of production of molecular mediator of immune response; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0050776 regulation of immune response; GO:0050789 regulation of biological process; GO:0002684 positive regulation of immune system process; GO:0048583 regulation of response to stimulus; GO:0002784 regulation of antimicrobial peptide production; GO:0002833 positive regulation of response to biotic stimulus; GO:0022411 cellular component disassembly; GO:0002682 regulation of immune system process; GO:0002803 positive regulation of antibacterial peptide production; GO:0048584 positive regulation of response to stimulus; GO:0048856 anatomical structure development; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0042599 lamellar body; GO:0005623 cell; GO:0005576 extracellular region; GO:0097209 epidermal lamellar body; GO:0043226 organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0004252 serine-type endopeptidase activity; GO:0004175 endopeptidase activity; GO:0004222 metalloendopeptidase activity; GO:0008233 peptidase activity; GO:0003824 catalytic activity; GO:0017171 serine hydrolase activity; GO:0008236 serine-type peptidase activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0008237 metallopeptidase activity; GO:0016787 hydrolase activity; ","K08668",null,null,"IPR009003; IPR001254; ","\"Peptidase S1, PA clan; Serine proteases, trypsin domain; \"\r"]
["P49915","GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS","GMPS",76.715,63.378,21.8,14,17,14,0.908,0.899,0.914,1.14,1.061,1.107,1.216,0.000802,"cyto_nucl\r","GO:0046148 pigment biosynthetic process; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009163 nucleoside biosynthetic process; GO:0046129 purine ribonucleoside biosynthetic process; GO:0009058 biosynthetic process; GO:0009156 ribonucleoside monophosphate biosynthetic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0046390 ribose phosphate biosynthetic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:1901068 guanosine-containing compound metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:1901070 guanosine-containing compound biosynthetic process; GO:0046112 nucleobase biosynthetic process; GO:0019693 ribose phosphate metabolic process; GO:0046037 GMP metabolic process; GO:0018130 heterocycle biosynthetic process; GO:0009113 purine nucleobase biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009168 purine ribonucleoside monophosphate biosynthetic process; GO:0042451 purine nucleoside biosynthetic process; GO:0090407 organophosphate biosynthetic process; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0072522 purine-containing compound biosynthetic process; GO:0009112 nucleobase metabolic process; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0006164 purine nucleotide biosynthetic process; GO:0006082 organic acid metabolic process; GO:0043436 oxoacid metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0009165 nucleotide biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0009259 ribonucleotide metabolic process; GO:0006541 glutamine metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009119 ribonucleoside metabolic process; GO:0009987 cellular process; GO:0009064 glutamine family amino acid metabolic process; GO:0009124 nucleoside monophosphate biosynthetic process; GO:0044711 single-organism biosynthetic process; GO:0042440 pigment metabolic process; GO:0009127 purine nucleoside monophosphate biosynthetic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0006177 GMP biosynthetic process; GO:0042455 ribonucleoside biosynthetic process; GO:0044238 primary metabolic process; GO:0006144 purine nucleobase metabolic process; GO:1901605 alpha-amino acid metabolic process; GO:1901576 organic substance biosynthetic process; GO:0006163 purine nucleotide metabolic process; GO:0044249 cellular biosynthetic process; GO:0046128 purine ribonucleoside metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0009152 purine ribonucleotide biosynthetic process; GO:0006793 phosphorus metabolic process; GO:1901659 glycosyl compound biosynthetic process; GO:0009260 ribonucleotide biosynthetic process; GO:0019752 carboxylic acid metabolic process; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0044444 cytoplasmic part; ","GO:0003922 GMP synthase (glutamine-hydrolyzing) activity; GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0003921 GMP synthase activity; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016874 ligase activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0000166 nucleotide binding; GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor; GO:0016879 ligase activity, forming carbon-nitrogen bonds; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K01951","guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]","hsa00230 Purine metabolism - Homo sapiens (human); hsa00983 Drug metabolism - other enzymes - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR014729; IPR004739; IPR001674; IPR017926; IPR025777; IPR029062; IPR022310; ","\"Rossmann-like alpha/beta/alpha sandwich fold; GMP synthase, glutamine amidotransferase; GMP synthase, C-terminal; Glutamine amidotransferase; GMP synthetase ATP pyrophosphatase domain; Class I glutamine amidotransferase-like; NAD/GMP synthase; \"\r"]
["P49916","DNA ligase 3 OS=Homo sapiens OX=9606 GN=LIG3","LIG3",112.91,10.692,5.2,4,4,4,0.963,1.076,1.027,1.02,0.978,0.95,0.962,0.369,"nucleus\r","GO:0006266 DNA ligation; GO:1901859 negative regulation of mitochondrial DNA metabolic process; GO:0051129 negative regulation of cellular component organization; GO:0006289 nucleotide-excision repair; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0090329 regulation of DNA-dependent DNA replication; GO:0010821 regulation of mitochondrion organization; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0090296 regulation of mitochondrial DNA replication; GO:0007005 mitochondrion organization; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0043170 macromolecule metabolic process; GO:0006310 DNA recombination; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0006288 base-excision repair, DNA ligation; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0097681 double-strand break repair via alternative nonhomologous end joining; GO:0008156 negative regulation of DNA replication; GO:0010639 negative regulation of organelle organization; GO:0050789 regulation of biological process; GO:0051052 regulation of DNA metabolic process; GO:0090304 nucleic acid metabolic process; GO:0051053 negative regulation of DNA metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0051301 cell division; GO:0043504 mitochondrial DNA repair; GO:0006297 nucleotide-excision repair, DNA gap filling; GO:0006303 double-strand break repair via nonhomologous end joining; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:2000104 negative regulation of DNA-dependent DNA replication; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0016043 cellular component organization; GO:0006260 DNA replication; GO:0006725 cellular aromatic compound metabolic process; GO:0006283 transcription-coupled nucleotide-excision repair; GO:0006275 regulation of DNA replication; GO:0006259 DNA metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0006302 double-strand break repair; GO:0032042 mitochondrial DNA metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:1901858 regulation of mitochondrial DNA metabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0071897 DNA biosynthetic process; GO:0009059 macromolecule biosynthetic process; GO:0000002 mitochondrial genome maintenance; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0009987 cellular process; GO:0000724 double-strand break repair via homologous recombination; GO:0010823 negative regulation of mitochondrion organization; GO:0006284 base-excision repair; GO:0006950 response to stress; GO:0000726 non-recombinational repair; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0033043 regulation of organelle organization; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0051103 DNA ligation involved in DNA repair; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0006974 cellular response to DNA damage stimulus; GO:0044249 cellular biosynthetic process; GO:0009890 negative regulation of biosynthetic process; GO:0006281 DNA repair; GO:0000725 recombinational repair; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006996 organelle organization; GO:0051128 regulation of cellular component organization; GO:0031327 negative regulation of cellular biosynthetic process; GO:0007049 cell cycle; GO:0065007 biological regulation; GO:0090298 negative regulation of mitochondrial DNA replication; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0070421 DNA ligase III-XRCC1 complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0003677 DNA binding; GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0003910 DNA ligase (ATP) activity; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016874 ligase activity; GO:0016886 ligase activity, forming phosphoric ester bonds; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0003909 DNA ligase activity; GO:0008270 zinc ion binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0046914 transition metal ion binding; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0003676 nucleic acid binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K10776","LIG3; DNA ligase 3 [EC:6.5.1.1]","hsa03410 Base excision repair - Homo sapiens (human); ","IPR012340; IPR012308; IPR012310; IPR001510; IPR012309; IPR031916; IPR001357; ","\"Nucleic acid-binding, OB-fold; DNA ligase, ATP-dependent, N-terminal; DNA ligase, ATP-dependent, central; Zinc finger, PARP-type; DNA ligase, ATP-dependent, C-terminal; DNA ligase 3, BRCT domain; BRCT domain; \"\r"]
["P50135","Histamine N-methyltransferase OS=Homo sapiens OX=9606 GN=HNMT","HNMT",33.295,7.8985,9.2,3,5,3,1.186,1.174,1.057,0.87,0.859,0.882,0.764,0.00206,"cytoplasm\r","GO:0001505 regulation of neurotransmitter levels; GO:1901606 alpha-amino acid catabolic process; GO:0065008 regulation of biological quality; GO:1903955 positive regulation of protein targeting to mitochondrion; GO:0007420 brain development; GO:1903533 regulation of protein targeting; GO:0052803 imidazole-containing compound metabolic process; GO:0044699 single-organism process; GO:0070555 response to interleukin-1; GO:0044237 cellular metabolic process; GO:0010821 regulation of mitochondrion organization; GO:0032259 methylation; GO:1903749 positive regulation of establishment of protein localization to mitochondrion; GO:0009607 response to biotic stimulus; GO:0014075 response to amine; GO:0051130 positive regulation of cellular component organization; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:1903747 regulation of establishment of protein localization to mitochondrion; GO:0032879 regulation of localization; GO:0048545 response to steroid hormone; GO:0009719 response to endogenous stimulus; GO:1901361 organic cyclic compound catabolic process; GO:0060322 head development; GO:0044106 cellular amine metabolic process; GO:0052805 imidazole-containing compound catabolic process; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0014070 response to organic cyclic compound; GO:0006970 response to osmotic stress; GO:0034097 response to cytokine; GO:0060359 response to ammonium ion; GO:0006548 histidine catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0032386 regulation of intracellular transport; GO:0032501 multicellular organismal process; GO:0051384 response to glucocorticoid; GO:0051050 positive regulation of transport; GO:0046395 carboxylic acid catabolic process; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0010243 response to organonitrogen compound; GO:0048513 animal organ development; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0010638 positive regulation of organelle organization; GO:0044710 single-organism metabolic process; GO:0007417 central nervous system development; GO:0009310 amine catabolic process; GO:1901698 response to nitrogen compound; GO:0002347 response to tumor cell; GO:0009063 cellular amino acid catabolic process; GO:0051223 regulation of protein transport; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:0042220 response to cocaine; GO:0043436 oxoacid metabolic process; GO:0051222 positive regulation of protein transport; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0090316 positive regulation of intracellular protein transport; GO:0006725 cellular aromatic compound metabolic process; GO:0009628 response to abiotic stimulus; GO:1903829 positive regulation of cellular protein localization; GO:1901700 response to oxygen-containing compound; GO:0043279 response to alkaloid; GO:0097164 ammonium ion metabolic process; GO:0042135 neurotransmitter catabolic process; GO:0050896 response to stimulus; GO:0070201 regulation of establishment of protein localization; GO:0006576 cellular biogenic amine metabolic process; GO:0060341 regulation of cellular localization; GO:0071704 organic substance metabolic process; GO:0033993 response to lipid; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0006547 histidine metabolic process; GO:0035902 response to immobilization stress; GO:0042133 neurotransmitter metabolic process; GO:0031960 response to corticosteroid; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0032880 regulation of protein localization; GO:0007275 multicellular organism development; GO:0001692 histamine metabolic process; GO:0033157 regulation of intracellular protein transport; GO:0009987 cellular process; GO:0009308 amine metabolic process; GO:0006950 response to stress; GO:0032388 positive regulation of intracellular transport; GO:0051049 regulation of transport; GO:0048731 system development; GO:0044712 single-organism catabolic process; GO:0006972 hyperosmotic response; GO:0033043 regulation of organelle organization; GO:0006807 nitrogen compound metabolic process; GO:0044282 small molecule catabolic process; GO:1903214 regulation of protein targeting to mitochondrion; GO:0042402 cellular biogenic amine catabolic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901605 alpha-amino acid metabolic process; GO:0048518 positive regulation of biological process; GO:0010822 positive regulation of mitochondrion organization; GO:0007585 respiratory gaseous exchange; GO:1901565 organonitrogen compound catabolic process; GO:0001695 histamine catabolic process; GO:1904951 positive regulation of establishment of protein localization; GO:0044767 single-organism developmental process; GO:0019752 carboxylic acid metabolic process; GO:0016054 organic acid catabolic process; GO:0051128 regulation of cellular component organization; GO:0009725 response to hormone; GO:0009056 catabolic process; GO:1903827 regulation of cellular protein localization; GO:0046700 heterocycle catabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0042995 cell projection; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0046539 histamine N-methyltransferase activity; GO:0008757 S-adenosylmethionine-dependent methyltransferase activity; GO:0016741 transferase activity, transferring one-carbon groups; GO:0008168 methyltransferase activity; GO:0008170 N-methyltransferase activity; GO:0003824 catalytic activity; GO:0016740 transferase activity; ","K00546","HNMT; histamine N-methyltransferase [EC:2.1.1.8]","hsa00340 Histidine metabolism - Homo sapiens (human); ","IPR029063; ","S-adenosyl-L-methionine-dependent methyltransferase; \r"]
["P50213","Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=IDH3A","IDH3A",39.591,40.303,30.3,9,11,9,0.912,0.954,1.004,1.045,1.054,1.092,1.112,0.0259,"cytoplasm\r","GO:0072350 tricarboxylic acid metabolic process; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006099 tricarboxylic acid cycle; GO:0044699 single-organism process; GO:0005975 carbohydrate metabolic process; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0045333 cellular respiration; GO:0071704 organic substance metabolic process; GO:0006101 citrate metabolic process; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0044710 single-organism metabolic process; GO:0009060 aerobic respiration; GO:0015980 energy derivation by oxidation of organic compounds; GO:0019752 carboxylic acid metabolic process; GO:0006082 organic acid metabolic process; GO:0009987 cellular process; GO:0043436 oxoacid metabolic process; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0043209 myelin sheath; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0000287 magnesium ion binding; GO:1901265 nucleoside phosphate binding; GO:0043167 ion binding; GO:0004448 isocitrate dehydrogenase activity; GO:0000166 nucleotide binding; GO:0048037 cofactor binding; GO:0016491 oxidoreductase activity; GO:0016614 oxidoreductase activity, acting on CH-OH group of donors; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; GO:0003824 catalytic activity; GO:0051287 NAD binding; GO:0005488 binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0004449 isocitrate dehydrogenase (NAD+) activity; GO:0036094 small molecule binding; GO:0050662 coenzyme binding; ","K00030","IDH3; isocitrate dehydrogenase (NAD+) [EC:1.1.1.41]","hsa01210 2-Oxocarboxylic acid metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00020 Citrate cycle (TCA cycle) - Homo sapiens (human); hsa01230 Biosynthesis of amino acids - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); ","IPR024084; ","Isopropylmalate dehydrogenase-like domain; \r"]
["P50395","Rab GDP dissociation inhibitor beta OS=Homo sapiens OX=9606 GN=GDI2","GDI2",50.663,216.36,60.7,26,52,18,0.948,0.908,0.939,1.032,1.036,1.087,1.129,0.00466,"endoplasmic reticulum\r","GO:0044700 single organism signaling; GO:0045321 leukocyte activation; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0044093 positive regulation of molecular function; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0051056 regulation of small GTPase mediated signal transduction; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0055114 oxidation-reduction process; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0007264 small GTPase mediated signal transduction; GO:0023052 signaling; GO:0002444 myeloid leukocyte mediated immunity; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:0032940 secretion by cell; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0065009 regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0043299 leukocyte degranulation; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0050896 response to stimulus; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0051345 positive regulation of hydrolase activity; GO:0036230 granulocyte activation; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:1902531 regulation of intracellular signal transduction; GO:0035556 intracellular signal transduction; GO:0043547 positive regulation of GTPase activity; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0071702 organic substance transport; GO:0043312 neutrophil degranulation; GO:0002263 cell activation involved in immune response; GO:0043085 positive regulation of catalytic activity; GO:0002366 leukocyte activation involved in immune response; GO:0045184 establishment of protein localization; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0061024 membrane organization; GO:0001775 cell activation; GO:0051179 localization; GO:0006955 immune response; GO:0065007 biological regulation; GO:0006887 exocytosis; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0034774 secretory granule lumen; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0005925 focal adhesion; GO:0070013 intracellular organelle lumen; GO:0043209 myelin sheath; GO:0005622 intracellular; GO:0044464 cell part; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030055 cell-substrate junction; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0042582 azurophil granule; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0031267 small GTPase binding; GO:0003723 RNA binding; GO:0005092 GDP-dissociation inhibitor activity; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0030695 GTPase regulator activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0016491 oxidoreductase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0030234 enzyme regulator activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0005093 Rab GDP-dissociation inhibitor activity; GO:0003676 nucleic acid binding; GO:0051020 GTPase binding; GO:0008047 enzyme activator activity; GO:0019899 enzyme binding; GO:0005096 GTPase activator activity; ","K17255",null,null,"IPR023753; ","FAD/NAD(P)-binding domain; \r"]
["P50402","Emerin OS=Homo sapiens OX=9606 GN=EMD","EMD",28.994,25.565,14.6,3,3,3,1.002,1,1.082,1.04,0.907,0.982,0.95,0.331,"mitochondria\r","GO:0003012 muscle system process; GO:0010256 endomembrane system organization; GO:1903533 regulation of protein targeting; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:0090317 negative regulation of intracellular protein transport; GO:0044699 single-organism process; GO:0071363 cellular response to growth factor stimulus; GO:0042308 negative regulation of protein import into nucleus; GO:0008285 negative regulation of cell proliferation; GO:0048145 regulation of fibroblast proliferation; GO:0035412 regulation of catenin import into nucleus; GO:0042306 regulation of protein import into nucleus; GO:0010646 regulation of cell communication; GO:0048147 negative regulation of fibroblast proliferation; GO:0032879 regulation of localization; GO:0007084 mitotic nuclear envelope reassembly; GO:0046824 positive regulation of nucleocytoplasmic transport; GO:0070848 response to growth factor; GO:0032387 negative regulation of intracellular transport; GO:1900181 negative regulation of protein localization to nucleus; GO:0007519 skeletal muscle tissue development; GO:0046823 negative regulation of nucleocytoplasmic transport; GO:0070887 cellular response to chemical stimulus; GO:0031468 nuclear envelope reassembly; GO:0051051 negative regulation of transport; GO:0032502 developmental process; GO:0007077 mitotic nuclear envelope disassembly; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:1903828 negative regulation of cellular protein localization; GO:0009888 tissue development; GO:0060537 muscle tissue development; GO:0044763 single-organism cellular process; GO:0060828 regulation of canonical Wnt signaling pathway; GO:0032386 regulation of intracellular transport; GO:0060538 skeletal muscle organ development; GO:0032501 multicellular organismal process; GO:0051050 positive regulation of transport; GO:0048513 animal organ development; GO:0030397 membrane disassembly; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0007517 muscle organ development; GO:0046825 regulation of protein export from nucleus; GO:0048583 regulation of response to stimulus; GO:1900180 regulation of protein localization to nucleus; GO:0051223 regulation of protein transport; GO:0048856 anatomical structure development; GO:0051222 positive regulation of protein transport; GO:0014706 striated muscle tissue development; GO:0050794 regulation of cellular process; GO:0006997 nucleus organization; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0042127 regulation of cell proliferation; GO:0090316 positive regulation of intracellular protein transport; GO:1903829 positive regulation of cellular protein localization; GO:0071310 cellular response to organic substance; GO:1904589 regulation of protein import; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:1904590 negative regulation of protein import; GO:0050896 response to stimulus; GO:1903047 mitotic cell cycle process; GO:0070201 regulation of establishment of protein localization; GO:0006998 nuclear envelope organization; GO:0060341 regulation of cellular localization; GO:0030154 cell differentiation; GO:0006936 muscle contraction; GO:0051081 nuclear envelope disassembly; GO:0035914 skeletal muscle cell differentiation; GO:0061061 muscle structure development; GO:0035414 negative regulation of catenin import into nucleus; GO:0007275 multicellular organism development; GO:0032880 regulation of protein localization; GO:0009987 cellular process; GO:0009966 regulation of signal transduction; GO:0033157 regulation of intracellular protein transport; GO:0003008 system process; GO:0051224 negative regulation of protein transport; GO:0048731 system development; GO:0032388 positive regulation of intracellular transport; GO:0051049 regulation of transport; GO:0044802 single-organism membrane organization; GO:0010033 response to organic substance; GO:0048518 positive regulation of biological process; GO:0046827 positive regulation of protein export from nucleus; GO:1904951 positive regulation of establishment of protein localization; GO:0046822 regulation of nucleocytoplasmic transport; GO:0030111 regulation of Wnt signaling pathway; GO:0044767 single-organism developmental process; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0022411 cellular component disassembly; GO:1904950 negative regulation of establishment of protein localization; GO:0022402 cell cycle process; GO:0007049 cell cycle; GO:1903827 regulation of cellular protein localization; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0019867 outer membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0005874 microtubule; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0005640 nuclear outer membrane; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0031965 nuclear membrane; GO:0015630 microtubule cytoskeleton; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0019866 organelle inner membrane; GO:0031968 organelle outer membrane; GO:0043227 membrane-bounded organelle; GO:0005637 nuclear inner membrane; GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005635 nuclear envelope; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0012505 endomembrane system; GO:0016021 integral component of membrane; GO:0099081 supramolecular polymer; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0031975 envelope; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0050839 cell adhesion molecule binding; GO:0008092 cytoskeletal protein binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0015631 tubulin binding; GO:0003779 actin binding; GO:0005515 protein binding; GO:0048487 beta-tubulin binding; ","K12569","EMD; emerin","hsa05414 Dilated cardiomyopathy (DCM) - Homo sapiens (human); hsa05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human); hsa05410 Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human); ","IPR003887; IPR011015; ","LEM domain; LEM/LEM-like domain; \r"]
["P50452","Serpin B8 OS=Homo sapiens OX=9606 GN=SERPINB8","SERPINB8",42.766,12.737,13.9,5,6,4,0.977,0.794,0.82,1.105,1.212,1.082,1.312,0.02,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0010951 negative regulation of endopeptidase activity; GO:0060255 regulation of macromolecule metabolic process; GO:0044699 single-organism process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0051346 negative regulation of hydrolase activity; GO:0090136 epithelial cell-cell adhesion; GO:0010466 negative regulation of peptidase activity; GO:0022610 biological adhesion; GO:0016337 single organismal cell-cell adhesion; GO:0007155 cell adhesion; GO:0052548 regulation of endopeptidase activity; GO:0045861 negative regulation of proteolysis; GO:0080090 regulation of primary metabolic process; GO:0098609 cell-cell adhesion; GO:0030162 regulation of proteolysis; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0009892 negative regulation of metabolic process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0051246 regulation of protein metabolic process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0098602 single organism cell adhesion; GO:0065009 regulation of molecular function; GO:0051248 negative regulation of protein metabolic process; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0052547 regulation of peptidase activity; GO:0065007 biological regulation; ","GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0004867 serine-type endopeptidase inhibitor activity; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0030414 peptidase inhibitor activity; GO:0061134 peptidase regulator activity; GO:0005515 protein binding; GO:0061135 endopeptidase regulator activity; GO:0098772 molecular function regulator; GO:0004857 enzyme inhibitor activity; GO:0004866 endopeptidase inhibitor activity; ","K13965",null,null,"IPR023796; ","Serpin domain; \r"]
["P50453","Serpin B9 OS=Homo sapiens OX=9606 GN=SERPINB9","SERPINB9",42.403,33.284,29,10,13,9,1.073,0.937,1.039,1.002,0.947,0.99,0.964,0.47,"extracellular\r","GO:0065008 regulation of biological quality; GO:0010941 regulation of cell death; GO:0043627 response to estrogen; GO:0002698 negative regulation of immune effector process; GO:0044699 single-organism process; GO:0052040 modulation by symbiont of host programmed cell death; GO:0035821 modification of morphology or physiology of other organism; GO:0031347 regulation of defense response; GO:0052150 modulation by symbiont of host apoptotic process; GO:0044068 modulation by symbiont of host cellular process; GO:0009607 response to biotic stimulus; GO:0009605 response to external stimulus; GO:0010466 negative regulation of peptidase activity; GO:0045088 regulation of innate immune response; GO:0009893 positive regulation of metabolic process; GO:0006915 apoptotic process; GO:0044003 modification by symbiont of host morphology or physiology; GO:0050777 negative regulation of immune response; GO:0044419 interspecies interaction between organisms; GO:0002697 regulation of immune effector process; GO:0070887 cellular response to chemical stimulus; GO:0052548 regulation of endopeptidase activity; GO:0051716 cellular response to stimulus; GO:0010468 regulation of gene expression; GO:0002443 leukocyte mediated immunity; GO:2000116 regulation of cysteine-type endopeptidase activity; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0002716 negative regulation of natural killer cell mediated immunity; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051704 multi-organism process; GO:0002444 myeloid leukocyte mediated immunity; GO:0050776 regulation of immune response; GO:0002683 negative regulation of immune system process; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0044532 modulation of apoptotic process in other organism; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0048583 regulation of response to stimulus; GO:0042269 regulation of natural killer cell mediated cytotoxicity; GO:0010604 positive regulation of macromolecule metabolic process; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0002682 regulation of immune system process; GO:0044092 negative regulation of molecular function; GO:0052547 regulation of peptidase activity; GO:0060548 negative regulation of cell death; GO:0033668 negative regulation by symbiont of host apoptotic process; GO:0050794 regulation of cellular process; GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0010951 negative regulation of endopeptidase activity; GO:0043069 negative regulation of programmed cell death; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0031341 regulation of cell killing; GO:0043067 regulation of programmed cell death; GO:0002704 negative regulation of leukocyte mediated immunity; GO:0052433 modulation by organism of apoptotic process in other organism involved in symbiotic interaction; GO:0002715 regulation of natural killer cell mediated immunity; GO:0044531 modulation of programmed cell death in other organism; GO:0043207 response to external biotic stimulus; GO:0080134 regulation of response to stress; GO:0031324 negative regulation of cellular metabolic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0002706 regulation of lymphocyte mediated immunity; GO:0051346 negative regulation of hydrolase activity; GO:0051817 modification of morphology or physiology of other organism involved in symbiotic interaction; GO:0045953 negative regulation of natural killer cell mediated cytotoxicity; GO:0043066 negative regulation of apoptotic process; GO:0010628 positive regulation of gene expression; GO:0052248 modulation of programmed cell death in other organism involved in symbiotic interaction; GO:2000117 negative regulation of cysteine-type endopeptidase activity; GO:0002448 mast cell mediated immunity; GO:0002707 negative regulation of lymphocyte mediated immunity; GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0009987 cellular process; GO:0009617 response to bacterium; GO:0031348 negative regulation of defense response; GO:0045861 negative regulation of proteolysis; GO:0001910 regulation of leukocyte mediated cytotoxicity; GO:0052041 negative regulation by symbiont of host programmed cell death; GO:0031342 negative regulation of cell killing; GO:0002376 immune system process; GO:0048585 negative regulation of response to stimulus; GO:0030162 regulation of proteolysis; GO:0051701 interaction with host; GO:0009892 negative regulation of metabolic process; GO:0048518 positive regulation of biological process; GO:0052490 negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction; GO:0002703 regulation of leukocyte mediated immunity; GO:0045824 negative regulation of innate immune response; GO:0008219 cell death; GO:0051246 regulation of protein metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0012501 programmed cell death; GO:0006955 immune response; GO:0042270 protection from natural killer cell mediated cytotoxicity; GO:0001911 negative regulation of leukocyte mediated cytotoxicity; GO:0071391 cellular response to estrogen stimulus; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process; GO:0061134 peptidase regulator activity; GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process; GO:0005515 protein binding; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0004866 endopeptidase inhibitor activity; GO:0004869 cysteine-type endopeptidase inhibitor activity; GO:0002020 protease binding; GO:0004867 serine-type endopeptidase inhibitor activity; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0030414 peptidase inhibitor activity; GO:0061135 endopeptidase regulator activity; GO:0019899 enzyme binding; ","K13963","SERPINB; serpin B","hsa05146 Amoebiasis - Homo sapiens (human); ","IPR023796; ","Serpin domain; \r"]
["P50570","Dynamin-2 OS=Homo sapiens OX=9606 GN=DNM2","DNM2",98.063,127.18,25.1,23,28,16,0.963,0.949,1.004,1.043,1.001,1.066,1.067,0.0617,"cytoplasm\r",{"$cut":{"chars":18177,"head":"GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0022414 reproductive process; GO:0009891 positive regulation of biosynthetic process; GO:0044237 cellular metabolic process; GO:0001558 regulation of cell growth; GO:0099003 vesicle-mediated transport in synapse; GO:0008152 metabolic process; GO:0065003 macromolecular complex assembly; GO:0032535 regulation of cellular component size; GO:0044093 positive regulation of molecular function; GO:0044770 cell cycle phase transition; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0071214 cellular response to abiotic stimulus; GO:0060359 response to ammonium ion; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:1900026 positive regulation of substrate adhesion-dependent cell spreading; GO:0044763 single-organism cellular process; GO:0090287 regulation of cellular response to growth factor stimulus; GO:0051704 multi-organism process; GO:0010811 positive regulation of cell-substrate adhesion; GO:0060976 coronary vasculature development; GO:0006810 transport; GO:1902745 positive regulation of lamellipodium organization; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0010243 response to organonitrogen compound; GO:0071731 response to nitric oxide; GO:1903350 response to dopamine; GO:0032768 regulation of monooxygenase activity; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0032781 positive regulation of ATPase activity; GO:0032412 regulation of ion transmembrane transporter activity; GO:0048609 multicellular organismal reproductive process; GO:0010975 regulation of neuron projection development; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0000003 reproduction; GO:0072359 circulatory system development; GO:0051640 organelle localization; GO:0044707 single-multicellular organism process; GO:0002028 regulation of sodium ion transport; GO:0030001 metal ion transport; GO:1901700 response to oxygen-containing compound; GO:0090148 membrane fission; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0003281 ventricular septum development; GO:0009653 anatomical structure morphogenesis; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0051345 positive regulation of hydrolase activity; GO:0009889 regulation of biosynthetic process; GO:0031345 negative regulation of cell projection organization; GO:0010959 regulation of metal ion transport; GO:0022401 negative adaptation of signaling pathway; GO:1902680 positive regulation of RNA biosynthetic process; GO:1902580 single-organism cellular localization; GO:0003231 cardiac ventricle development; GO:0032409 regulation of transporter activity; GO:0030100 regulation of endocytosis; GO:1901381 positive regulation of potassium ion transmembrane transport; GO:0009416 response to light stimulus; GO:0006950 response to stress; GO:0045785 positive regulation of cell adhesion; GO:0051960 regulation of nervous system development; GO:1901379 regulation of potassium ion transmembrane transport; GO:0060284 regulation of cell development; GO:0050766 positive regulation of phagocytosis; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0097480 establishment of synaptic vesicle localization; GO:1904064 positive regulation of cation transmembrane transport; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0071870 cellular response to catecholamine stimulus; GO:0044839 cell cycle G2/M phase transition; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:0006892 post-Golgi vesicle-mediated transport; GO:0031623 receptor internalization; GO:00099"}},"GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0045334 clathrin-coated endocytic vesicle; GO:0032587 ruffle membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0001917 photoreceptor inner segment; GO:0005925 focal adhesion; GO:0098590 plasma membrane region; GO:0031256 leading edge membrane; GO:0030136 clathrin-coated vesicle; GO:0005622 intracellular; GO:0098791 Golgi subcompartment; GO:0098589 membrane region; GO:0014069 postsynaptic density; GO:0030027 lamellipodium; GO:0097060 synaptic membrane; GO:0043005 neuron projection; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0005924 cell-substrate adherens junction; GO:0031252 cell leading edge; GO:0099513 polymeric cytoskeletal fiber; GO:0042995 cell projection; GO:0030666 endocytic vesicle membrane; GO:0044430 cytoskeletal part; GO:0031967 organelle envelope; GO:0030496 midbody; GO:0070161 anchoring junction; GO:0012506 vesicle membrane; GO:0030427 site of polarized growth; GO:0005576 extracellular region; GO:0030135 coated vesicle; GO:0005739 mitochondrion; GO:0099081 supramolecular polymer; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0098794 postsynapse; GO:0031975 envelope; GO:0005905 clathrin-coated pit; GO:0043234 protein complex; GO:0099572 postsynaptic specialization; GO:0031966 mitochondrial membrane; GO:0043230 extracellular organelle; GO:0005874 microtubule; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0031982 vesicle; GO:0030426 growth cone; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0032279 asymmetric synapse; GO:0005856 cytoskeleton; GO:0005740 mitochondrial envelope; GO:0005815 microtubule organizing center; GO:0015630 microtubule cytoskeleton; GO:0044464 cell part; GO:0044425 membrane part; GO:0030670 phagocytic vesicle membrane; GO:0098805 whole membrane; GO:0001891 phagocytic cup; GO:1903561 extracellular vesicle; GO:0005912 adherens junction; GO:0044431 Golgi apparatus part; GO:0048471 perinuclear region of cytoplasm; GO:0005768 endosome; GO:0030139 endocytic vesicle; GO:0098984 neuron to neuron synapse; GO:0044456 synapse part; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0045335 phagocytic vesicle; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0045202 synapse; GO:0045211 postsynaptic membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0005813 centrosome; GO:0005802 trans-Golgi network; GO:0001726 ruffle; GO:0031253 cell projection membrane; GO:0005794 Golgi apparatus; GO:0031984 organelle subcompartment; GO:0044444 cytoplasmic part; ","GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding; GO:1901265 nucleoside phosphate binding; GO:0005102 receptor binding; GO:0019901 protein kinase binding; GO:0050998 nitric-oxide synthase binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0031749 D2 dopamine receptor binding; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0050780 dopamine receptor binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0008092 cytoskeletal protein binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0008017 microtubule binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0003924 GTPase activity; GO:0043168 anion binding; GO:0001664 G-protein coupled receptor binding; GO:0019001 guanyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0015631 tubulin binding; GO:0050699 WW domain binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0019900 kinase binding; GO:0017124 SH3 domain binding; GO:0043548 phosphatidylinositol 3-kinase binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032555 purine ribonucleotide binding; GO:0019904 protein domain specific binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019899 enzyme binding; GO:0032403 protein complex binding; GO:0036094 small molecule binding; ","K01528","DNM; dynamin GTPase [EC:3.6.5.5]","hsa05100 Bacterial invasion of epithelial cells - Homo sapiens (human); hsa04666 Fc gamma R-mediated phagocytosis - Homo sapiens (human); hsa04072 Phospholipase D signaling pathway - Homo sapiens (human); hsa04144 Endocytosis - Homo sapiens (human); hsa04961 Endocrine and other factor-regulated calcium reabsorption - Homo sapiens (human); hsa04721 Synaptic vesicle cycle - Homo sapiens (human); ","IPR030381; IPR003130; IPR011993; IPR001401; IPR020850; IPR027417; IPR000375; IPR001849; ","\"Dynamin-type guanine nucleotide-binding (G) domain; Dynamin GTPase effector; PH domain-like; Dynamin, GTPase domain; GTPase effector domain; P-loop containing nucleoside triphosphate hydrolase; Dynamin central domain; Pleckstrin homology domain; \"\r"]
["P50583","Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] OS=Homo sapiens OX=9606 GN=NUDT2","NUDT2",16.829,24.943,41.5,4,5,4,1.082,0.933,1.032,1.007,0.932,1.023,0.972,0.63,"mitochondria\r","GO:0006950 response to stress; GO:0006725 cellular aromatic compound metabolic process; GO:0000302 response to reactive oxygen species; GO:1901700 response to oxygen-containing compound; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0050896 response to stimulus; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0042221 response to chemical; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0008219 cell death; GO:0006915 apoptotic process; GO:0006979 response to oxidative stress; GO:0034641 cellular nitrogen compound metabolic process; GO:0012501 programmed cell death; GO:0009987 cellular process; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0004551 nucleotide diphosphatase activity; GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0008803 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity; GO:0000166 nucleotide binding; GO:0008796 bis(5'-nucleosyl)-tetraphosphatase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0004081 bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity; GO:0097367 carbohydrate derivative binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019001 guanyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0036094 small molecule binding; ","K01518","NUDT2; bis(5'-nucleosidyl)-tetraphosphatase [EC:3.6.1.17]","hsa00230 Purine metabolism - Homo sapiens (human); hsa00240 Pyrimidine metabolism - Homo sapiens (human); ","IPR015797; IPR000086; ","NUDIX hydrolase domain-like; NUDIX hydrolase domain; \r"]
["P50897","Palmitoyl-protein thioesterase 1 OS=Homo sapiens OX=9606 GN=PPT1","PPT1",34.193,29.886,15.7,4,5,4,1.09,1.125,1.189,0.854,0.956,0.808,0.769,0.00896,"extracellular\r","GO:0060627 regulation of vesicle-mediated transport; GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0065008 regulation of biological quality; GO:0007601 visual perception; GO:0007420 brain development; GO:0035337 fatty-acyl-CoA metabolic process; GO:0043523 regulation of neuron apoptotic process; GO:0098734 macromolecule depalmitoylation; GO:0030641 regulation of cellular pH; GO:0030004 cellular monovalent inorganic cation homeostasis; GO:0007269 neurotransmitter secretion; GO:0044255 cellular lipid metabolic process; GO:0007625 grooming behavior; GO:0044237 cellular metabolic process; GO:0044272 sulfur compound biosynthetic process; GO:0042157 lipoprotein metabolic process; GO:0015031 protein transport; GO:0050877 neurological system process; GO:0048549 positive regulation of pinocytosis; GO:0001558 regulation of cell growth; GO:0007610 behavior; GO:0008152 metabolic process; GO:0032879 regulation of localization; GO:0009108 coenzyme biosynthetic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0008104 protein localization; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0006790 sulfur compound metabolic process; GO:0007399 nervous system development; GO:0048259 regulation of receptor-mediated endocytosis; GO:0002084 protein depalmitoylation; GO:0048699 generation of neurons; GO:0060191 regulation of lipase activity; GO:0044763 single-organism cellular process; GO:0006732 coenzyme metabolic process; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0048513 animal organ development; GO:0051336 regulation of hydrolase activity; GO:0007267 cell-cell signaling; GO:0007612 learning; GO:0035601 protein deacylation; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0007417 central nervous system development; GO:0030163 protein catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0060548 negative regulation of cell death; GO:0099643 signal release from synapse; GO:0044708 single-organism behavior; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0006885 regulation of pH; GO:0007035 vacuolar acidification; GO:0043067 regulation of programmed cell death; GO:0044267 cellular protein metabolic process; GO:0010517 regulation of phospholipase activity; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0043524 negative regulation of neuron apoptotic process; GO:1902578 single-organism localization; GO:0044248 cellular catabolic process; GO:0007042 lysosomal lumen acidification; GO:0006898 receptor-mediated endocytosis; GO:0007275 multicellular organism development; GO:0031579 membrane raft organization; GO:0030534 adult behavior; GO:0048878 chemical homeostasis; GO:1901215 negative regulation of neuron death; GO:0016042 lipid catabolic process; GO:0030100 regulation of endocytosis; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0035383 thioester metabolic process; GO:0071702 organic substance transport; GO:0023061 signal release; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0045184 establishment of protein localization; GO:0030182 neuron differentiation; GO:0099536 synaptic signaling; GO:0006793 phosphorus metabolic process; GO:0051453 regulation of intracellular pH; GO:0006873 cellular ion homeostasis; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0080171 lytic vacuole organization; GO:0044242 cellular lipid catabolic process; GO:0043412 macromolecule modification; GO:0051179 localization; GO:0007268 chemical synaptic transmission; GO:1901564 organonitrogen compound metabolic process; GO:0051188 cofactor biosynthetic process; GO:0001505 regulation of neurotransmitter levels; GO:0035751 regulation of lysosomal lumen pH; GO:0006643 membrane lipid metabolic process; GO:0048869 cellular developmental process; GO:0048666 neuron development; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0009058 biosynthetic process; GO:0035384 thioester biosynthetic process; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0060322 head development; GO:0006665 sphingolipid metabolic process; GO:0042159 lipoprotein catabolic process; GO:0007033 vacuole organization; GO:0098916 anterograde trans-synaptic signaling; GO:0033036 macromolecule localization; GO:0098732 macromolecule deacylation; GO:0006629 lipid metabolic process; GO:0032502 developmental process; GO:0045926 negative regulation of growth; GO:0007600 sensory perception; GO:0046466 membrane lipid catabolic process; GO:0050801 ion homeostasis; GO:0071616 acyl-CoA biosynthetic process; GO:0051181 cofactor transport; GO:0098771 inorganic ion homeostasis; GO:0019725 cellular homeostasis; GO:0048522 positive regulation of cellular process; GO:0035336 long-chain fatty-acyl-CoA metabolic process; GO:0023052 signaling; GO:0006907 pinocytosis; GO:0035338 long-chain fatty-acyl-CoA biosynthetic process; GO:0051186 cofactor metabolic process; GO:0007040 lysosome organization; GO:0051050 positive regulation of transport; GO:0030308 negative regulation of cell growth; GO:0050789 regulation of biological process; GO:0032940 secretion by cell; GO:0065009 regulation of molecular function; GO:0048548 regulation of pinocytosis; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0048260 positive regulation of receptor-mediated endocytosis; GO:0016043 cellular component organization; GO:0040008 regulation of growth; GO:0046949 fatty-acyl-CoA biosynthetic process; GO:0044257 cellular protein catabolic process; GO:0043069 negative regulation of programmed cell death; GO:0045851 pH reduction; GO:0008344 adult locomotory behavior; GO:0045807 positive regulation of endocytosis; GO:0030003 cellular cation homeostasis; GO:0099531 presynaptic process involved in chemical synaptic transmission; GO:0050896 response to stimulus; GO:0032429 regulation of phospholipase A2 activity; GO:0055082 cellular chemical homeostasis; GO:0048468 cell development; GO:0071704 organic substance metabolic process; GO:0030149 sphingolipid catabolic process; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:0055080 cation homeostasis; GO:0043066 negative regulation of apoptotic process; GO:0050890 cognition; GO:0099537 trans-synaptic signaling; GO:0009987 cellular process; GO:1901214 regulation of neuron death; GO:0055067 monovalent inorganic cation homeostasis; GO:0050803 regulation of synapse structure or activity; GO:0044265 cellular macromolecule catabolic process; GO:0003008 system process; GO:0051049 regulation of transport; GO:0044712 single-organism catabolic process; GO:0044802 single-organism membrane organization; GO:0006807 nitrogen compound metabolic process; GO:0050953 sensory perception of light stimulus; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0007611 learning or memory; GO:0006637 acyl-CoA metabolic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:1901565 organonitrogen compound catabolic process; GO:0044767 single-organism developmental process; GO:0009057 macromolecule catabolic process; GO:0007626 locomotory behavior; GO:0008306 associative learning; GO:0051452 intracellular pH reduction; GO:0051128 regulation of cellular component organization; GO:0009056 catabolic process; GO:0006836 neurotransmitter transport; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0030425 dendrite; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0098857 membrane microdomain; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0043025 neuronal cell body; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0031974 membrane-enclosed lumen; GO:0070382 exocytic vesicle; GO:0070062 extracellular exosome; GO:0070013 intracellular organelle lumen; GO:0008021 synaptic vesicle; GO:0044425 membrane part; GO:0005622 intracellular; GO:0098793 presynapse; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:0098589 membrane region; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0045121 membrane raft; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043233 organelle lumen; GO:0044456 synapse part; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0042995 cell projection; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0043202 lysosomal lumen; GO:0005576 extracellular region; GO:0045202 synapse; GO:0030424 axon; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0036477 somatodendritic compartment; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0044297 cell body; GO:0005794 Golgi apparatus; GO:0030133 transport vesicle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0098599 palmitoyl hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0047617 acyl-CoA hydrolase activity; GO:0016289 CoA hydrolase activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0016790 thiolester hydrolase activity; GO:0008474 palmitoyl-(protein) hydrolase activity; GO:0016290 palmitoyl-CoA hydrolase activity; ","K01074","PPT; palmitoyl-protein thioesterase [EC:3.1.2.22]","hsa04142 Lysosome - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa01212 Fatty acid metabolism - Homo sapiens (human); hsa00062 Fatty acid elongation - Homo sapiens (human); ","IPR029058; ","Alpha/Beta hydrolase fold; \r"]
["P50914","60S ribosomal protein L14 OS=Homo sapiens OX=9606 GN=RPL14","RPL14",23.432,13.674,10.7,2,6,2,0.902,0.941,0.947,1.063,1.087,1.029,1.139,0.0041,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0072594 establishment of protein localization to organelle; GO:0006518 peptide metabolic process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0042273 ribosomal large subunit biogenesis; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0051649 establishment of localization in cell; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0070972 protein localization to endoplasmic reticulum; GO:0006364 rRNA processing; GO:0006413 translational initiation; GO:1901361 organic cyclic compound catabolic process; GO:0033365 protein localization to organelle; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0006412 translation; GO:0016072 rRNA metabolic process; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0072657 protein localization to membrane; GO:0043043 peptide biosynthetic process; GO:0042254 ribosome biogenesis; GO:1901360 organic cyclic compound metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032774 RNA biosynthetic process; GO:0045047 protein targeting to ER; GO:0043603 cellular amide metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0006401 RNA catabolic process; GO:0016070 RNA metabolic process; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0019083 viral transcription; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0046907 intracellular transport; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0044267 cellular protein metabolic process; GO:0006613 cotranslational protein targeting to membrane; GO:0048519 negative regulation of biological process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0016032 viral process; GO:0019080 viral gene expression; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0006886 intracellular protein transport; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0034613 cellular protein localization; GO:0009059 macromolecule biosynthetic process; GO:0090150 establishment of protein localization to membrane; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0051179 localization; GO:0009056 catabolic process; GO:0034660 ncRNA metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0071840 cellular component organization or biogenesis; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; ","GO:0005840 ribosome; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0022625 cytosolic large ribosomal subunit; GO:0031982 vesicle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0015934 large ribosomal subunit; GO:0044391 ribosomal subunit; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0044445 cytosolic part; GO:1990904 ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0030529 intracellular ribonucleoprotein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0022626 cytosolic ribosome; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0050839 cell adhesion molecule binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0005198 structural molecule activity; GO:0003735 structural constituent of ribosome; ","K02875","RP-L14e; large subunit ribosomal protein L14e","hsa03010 Ribosome - Homo sapiens (human); ","IPR008991; IPR002784; IPR014722; ","Translation protein SH3-like domain; Ribosomal protein L14e domain; Ribosomal protein L2 domain 2; \r"]
["P51003","Poly(A) polymerase alpha OS=Homo sapiens OX=9606 GN=PAPOLA","PAPOLA",82.842,4.6838,1.3,1,3,1,0.869,0.913,0.939,1.192,1.088,1.022,1.214,0.0186,"nucleus\r","GO:0050794 regulation of cellular process; GO:0031123 RNA 3'-end processing; GO:0006725 cellular aromatic compound metabolic process; GO:0031124 mRNA 3'-end processing; GO:0060255 regulation of macromolecule metabolic process; GO:0006378 mRNA polyadenylation; GO:0097659 nucleic acid-templated transcription; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0006353 DNA-templated transcription, termination; GO:0000398 mRNA splicing, via spliceosome; GO:0008152 metabolic process; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0031440 regulation of mRNA 3'-end processing; GO:0000375 RNA splicing, via transesterification reactions; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0006396 RNA processing; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0043631 RNA polyadenylation; GO:0080090 regulation of primary metabolic process; GO:0006369 termination of RNA polymerase II transcription; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0050684 regulation of mRNA processing; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0044238 primary metabolic process; GO:0051252 regulation of RNA metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:1903311 regulation of mRNA metabolic process; GO:0050789 regulation of biological process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0006366 transcription from RNA polymerase II promoter; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0010467 gene expression; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031974 membrane-enclosed lumen; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0005515 protein binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0000287 magnesium ion binding; GO:0003723 RNA binding; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0070566 adenylyltransferase activity; GO:0030145 manganese ion binding; GO:0032549 ribonucleoside binding; GO:0004652 polynucleotide adenylyltransferase activity; GO:0097367 carbohydrate derivative binding; GO:0046914 transition metal ion binding; GO:0016779 nucleotidyltransferase activity; GO:0003676 nucleic acid binding; GO:0046872 metal ion binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0036094 small molecule binding; ","K14376","PAP; poly(A) polymerase [EC:2.7.7.19]","hsa03015 mRNA surveillance pathway - Homo sapiens (human); ","IPR007012; IPR011068; IPR002934; IPR007010; ","\"Poly(A) polymerase, central domain; Nucleotidyltransferase, class I, C-terminal-like; Polymerase, nucleotidyl transferase domain; Poly(A) polymerase, RNA-binding domain; \"\r"]
["P51114","Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1","FXR1",69.72,33.644,7.9,4,5,3,0.965,1.022,0.896,1.07,1.055,1,1.084,0.133,"nucleus\r","GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0060255 regulation of macromolecule metabolic process; GO:0010608 posttranscriptional regulation of gene expression; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0017148 negative regulation of translation; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0030154 cell differentiation; GO:0060964 regulation of gene silencing by miRNA; GO:0009889 regulation of biosynthetic process; GO:0006915 apoptotic process; GO:0060968 regulation of gene silencing; GO:0061061 muscle structure development; GO:0051171 regulation of nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0009987 cellular process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0060147 regulation of posttranscriptional gene silencing; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0010629 negative regulation of gene expression; GO:0048731 system development; GO:0060148 positive regulation of posttranscriptional gene silencing; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0034249 negative regulation of cellular amide metabolic process; GO:0060966 regulation of gene silencing by RNA; GO:0010556 regulation of macromolecule biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0048518 positive regulation of biological process; GO:0032501 multicellular organismal process; GO:0009892 negative regulation of metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0034248 regulation of cellular amide metabolic process; GO:0048513 animal organ development; GO:0009890 negative regulation of biosynthetic process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0008219 cell death; GO:0007517 muscle organ development; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0006417 regulation of translation; GO:0032269 negative regulation of cellular protein metabolic process; GO:0019222 regulation of metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0012501 programmed cell death; GO:0031327 negative regulation of cellular biosynthetic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:2000637 positive regulation of gene silencing by miRNA; GO:0048856 anatomical structure development; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0030425 dendrite; GO:0030016 myofibril; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0043197 dendritic spine; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0044309 neuron spine; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043292 contractile fiber; GO:0048471 perinuclear region of cytoplasm; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0044456 synapse part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0099081 supramolecular polymer; GO:0045202 synapse; GO:0030424 axon; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0036477 somatodendritic compartment; GO:0005634 nucleus; GO:0098794 postsynapse; GO:0043034 costamere; GO:0035770 ribonucleoprotein granule; GO:0044449 contractile fiber part; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0044444 cytoplasmic part; GO:0005844 polysome; GO:0044428 nuclear part; ","GO:0003723 RNA binding; GO:0097617 annealing activity; GO:0046982 protein heterodimerization activity; GO:0003725 double-stranded RNA binding; GO:0003730 mRNA 3'-UTR binding; GO:0046983 protein dimerization activity; GO:0002151 G-quadruplex RNA binding; GO:0005515 protein binding; GO:0003727 single-stranded RNA binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0003729 mRNA binding; GO:0042802 identical protein binding; GO:0005488 binding; GO:0042803 protein homodimerization activity; GO:0003676 nucleic acid binding; GO:0033592 RNA strand annealing activity; ","K15516","FMR; fragile X mental retardation protein","hsa03013 RNA transport - Homo sapiens (human); ","IPR004087; IPR032177; IPR022034; IPR008395; IPR004088; IPR032172; ","\"K Homology domain; Fragile X-related 1 protein, C-terminal region 3; Fragile X-related 1 protein, C-terminal core; Agenet-like domain; K Homology domain, type 1; Fragile X-related 1 protein, C-terminal region 1; \"\r"]
["P51151","Ras-related protein Rab-9A OS=Homo sapiens OX=9606 GN=RAB9A","RAB9A",22.837,41.612,26.9,4,6,4,1.025,0.96,1.069,1.015,0.943,1.006,0.971,0.491,"extracellular\r","GO:0044700 single organism signaling; GO:0050794 regulation of cellular process; GO:0060627 regulation of vesicle-mediated transport; GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0065008 regulation of biological quality; GO:0044359 modulation of molecular function in other organism; GO:0044699 single-organism process; GO:0051046 regulation of secretion; GO:0017157 regulation of exocytosis; GO:0035821 modification of morphology or physiology of other organism; GO:0050896 response to stimulus; GO:0044362 negative regulation of molecular function in other organism; GO:0015031 protein transport; GO:0051817 modification of morphology or physiology of other organism involved in symbiotic interaction; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0032879 regulation of localization; GO:0051702 interaction with symbiont; GO:0032880 regulation of protein localization; GO:0016482 cytosolic transport; GO:0044419 interspecies interaction between organisms; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0009987 cellular process; GO:0052428 modification by host of symbiont molecular function; GO:0051716 cellular response to stimulus; GO:0045921 positive regulation of exocytosis; GO:0035556 intracellular signal transduction; GO:0051049 regulation of transport; GO:0016192 vesicle-mediated transport; GO:0048522 positive regulation of cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0071702 organic substance transport; GO:0007264 small GTPase mediated signal transduction; GO:1903530 regulation of secretion by cell; GO:0023052 signaling; GO:0048518 positive regulation of biological process; GO:0051704 multi-organism process; GO:0051641 cellular localization; GO:0051050 positive regulation of transport; GO:0016197 endosomal transport; GO:0006810 transport; GO:0045184 establishment of protein localization; GO:0052205 modulation of molecular function in other organism involved in symbiotic interaction; GO:0052405 negative regulation by host of symbiont molecular function; GO:0050789 regulation of biological process; GO:0042147 retrograde transport, endosome to Golgi; GO:0052204 negative regulation of molecular function in other organism involved in symbiotic interaction; GO:1903532 positive regulation of secretion by cell; GO:0061024 membrane organization; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0051179 localization; GO:0051851 modification by host of symbiont morphology or physiology; GO:0071840 cellular component organization or biogenesis; GO:0051047 positive regulation of secretion; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032588 trans-Golgi network membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0048770 pigment granule; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005764 lysosome; GO:0030670 phagocytic vesicle membrane; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0098791 Golgi subcompartment; GO:0044431 Golgi apparatus part; GO:0005768 endosome; GO:0030139 endocytic vesicle; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0005770 late endosome; GO:0098588 bounding membrane of organelle; GO:0030666 endocytic vesicle membrane; GO:0042470 melanosome; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0045335 phagocytic vesicle; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044432 endoplasmic reticulum part; GO:0005802 trans-Golgi network; GO:0005773 vacuole; GO:0030133 transport vesicle; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0031984 organelle subcompartment; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016462 pyrophosphatase activity; GO:0019003 GDP binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0003924 GTPase activity; GO:0032550 purine ribonucleoside binding; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; ","K07899","RAB9A; Ras-related protein Rab-9A","hsa05162 Measles - Homo sapiens (human); ","IPR005225; IPR027417; ","Small GTP-binding protein domain; P-loop containing nucleoside triphosphate hydrolase; \r"]
["P51153","Ras-related protein Rab-13 OS=Homo sapiens OX=9606 GN=RAB13","RAB13",22.774,18.555,30.5,6,13,4,1.022,0.935,0.948,1.119,1.015,0.97,1.069,0.265,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0090130 tissue migration; GO:0022414 reproductive process; GO:0008584 male gonad development; GO:0090002 establishment of protein localization to plasma membrane; GO:1902463 protein localization to cell leading edge; GO:0015031 protein transport; GO:0097368 establishment of Sertoli cell barrier; GO:0009605 response to external stimulus; GO:0030036 actin cytoskeleton organization; GO:0043542 endothelial cell migration; GO:0044702 single organism reproductive process; GO:0009719 response to endogenous stimulus; GO:0008104 protein localization; GO:1901652 response to peptide; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0035767 endothelial cell chemotaxis; GO:0003006 developmental process involved in reproduction; GO:0002064 epithelial cell development; GO:0072657 protein localization to membrane; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0060008 Sertoli cell differentiation; GO:0007264 small GTPase mediated signal transduction; GO:0048870 cell motility; GO:0007009 plasma membrane organization; GO:0006935 chemotaxis; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:0010243 response to organonitrogen compound; GO:0048513 animal organ development; GO:0010631 epithelial cell migration; GO:1901698 response to nitrogen compound; GO:0032869 cellular response to insulin stimulus; GO:0042330 taxis; GO:0030855 epithelial cell differentiation; GO:0000003 reproduction; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:1901700 response to oxygen-containing compound; GO:0008406 gonad development; GO:0090132 epithelium migration; GO:0060326 cell chemotaxis; GO:1990778 protein localization to cell periphery; GO:0010737 protein kinase A signaling; GO:1902578 single-organism localization; GO:0007548 sex differentiation; GO:1902580 single-organism cellular localization; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0034613 cellular protein localization; GO:0061458 reproductive system development; GO:0090150 establishment of protein localization to membrane; GO:0043297 apical junction assembly; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0071702 organic substance transport; GO:0010033 response to organic substance; GO:0045184 establishment of protein localization; GO:0030182 neuron differentiation; GO:0072659 protein localization to plasma membrane; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0061024 membrane organization; GO:0006928 movement of cell or subcellular component; GO:0046546 development of primary male sexual characteristics; GO:0051179 localization; GO:0010256 endomembrane system organization; GO:0051674 localization of cell; GO:0048869 cellular developmental process; GO:0048666 neuron development; GO:0045216 cell-cell junction organization; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:0007154 cell communication; GO:1901653 cellular response to peptide; GO:0022607 cellular component assembly; GO:0033036 macromolecule localization; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0009888 tissue development; GO:0030866 cortical actin cytoskeleton organization; GO:0048608 reproductive structure development; GO:0023052 signaling; GO:0016197 endosomal transport; GO:0071417 cellular response to organonitrogen compound; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0032868 response to insulin; GO:0043434 response to peptide hormone; GO:0030030 cell projection organization; GO:1901699 cellular response to nitrogen compound; GO:0032870 cellular response to hormone stimulus; GO:0001667 ameboidal-type cell migration; GO:0040011 locomotion; GO:0048856 anatomical structure development; GO:0016043 cellular component organization; GO:0034329 cell junction assembly; GO:0016477 cell migration; GO:0046661 male sex differentiation; GO:0071310 cellular response to organic substance; GO:0050896 response to stimulus; GO:0030865 cortical cytoskeleton organization; GO:0048468 cell development; GO:0044795 trans-Golgi network to recycling endosome transport; GO:0030154 cell differentiation; GO:0071375 cellular response to peptide hormone stimulus; GO:0070830 bicellular tight junction assembly; GO:0009987 cellular process; GO:0045137 development of primary sexual characteristics; GO:0007043 cell-cell junction assembly; GO:0035556 intracellular signal transduction; GO:0044802 single-organism membrane organization; GO:0031175 neuron projection development; GO:0051641 cellular localization; GO:0070727 cellular macromolecule localization; GO:1901701 cellular response to oxygen-containing compound; GO:0034330 cell junction organization; GO:0060009 Sertoli cell development; GO:0044767 single-organism developmental process; GO:0071495 cellular response to endogenous stimulus; GO:0009725 response to hormone; GO:0032456 endocytic recycling; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0055038 recycling endosome membrane; GO:0044424 intracellular part; GO:0005911 cell-cell junction; GO:0005623 cell; GO:0044422 organelle part; GO:0055037 recycling endosome; GO:0070062 extracellular exosome; GO:0070160 occluding junction; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0098805 whole membrane; GO:0098791 Golgi subcompartment; GO:0030027 lamellipodium; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0043005 neuron projection; GO:0005768 endosome; GO:0030141 secretory granule; GO:0030139 endocytic vesicle; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0010008 endosome membrane; GO:0031252 cell leading edge; GO:0042995 cell projection; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0005829 cytosol; GO:0005923 bicellular tight junction; GO:0005576 extracellular region; GO:0016328 lateral plasma membrane; GO:0043296 apical junction complex; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0005802 trans-Golgi network; GO:0032593 insulin-responsive compartment; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0031984 organelle subcompartment; GO:0044444 cytoplasmic part; ","GO:0051018 protein kinase A binding; GO:1901265 nucleoside phosphate binding; GO:0019901 protein kinase binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0003924 GTPase activity; GO:0043168 anion binding; GO:0019001 guanyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0019900 kinase binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0032561 guanyl ribonucleotide binding; GO:0034236 protein kinase A catalytic subunit binding; GO:0019899 enzyme binding; GO:0036094 small molecule binding; ","K06109","RAB13; Ras-related protein Rab-13","hsa04530 Tight junction - Homo sapiens (human); ","IPR005225; IPR027417; ","Small GTP-binding protein domain; P-loop containing nucleoside triphosphate hydrolase; \r"]
["P51452","Dual specificity protein phosphatase 3 OS=Homo sapiens OX=9606 GN=DUSP3","DUSP3",20.478,15.666,23.8,3,4,3,1.02,0.994,1.032,1.013,1.027,0.925,0.973,0.466,"cytoplasm\r","GO:0050863 regulation of T cell activation; GO:0002694 regulation of leukocyte activation; GO:0032872 regulation of stress-activated MAPK cascade; GO:0009968 negative regulation of signal transduction; GO:0043009 chordate embryonic development; GO:0000188 inactivation of MAPK activity; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0051249 regulation of lymphocyte activation; GO:0050858 negative regulation of antigen receptor-mediated signaling pathway; GO:0044237 cellular metabolic process; GO:0031400 negative regulation of protein modification process; GO:0006796 phosphate-containing compound metabolic process; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0008152 metabolic process; GO:0070302 regulation of stress-activated protein kinase signaling cascade; GO:0010646 regulation of cell communication; GO:0071901 negative regulation of protein serine/threonine kinase activity; GO:0033673 negative regulation of kinase activity; GO:0032873 negative regulation of stress-activated MAPK cascade; GO:0070303 negative regulation of stress-activated protein kinase signaling cascade; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0002695 negative regulation of leukocyte activation; GO:0009790 embryo development; GO:0051726 regulation of cell cycle; GO:0046328 regulation of JNK cascade; GO:0032502 developmental process; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:1903038 negative regulation of leukocyte cell-cell adhesion; GO:0048522 positive regulation of cellular process; GO:0046329 negative regulation of JNK cascade; GO:0051348 negative regulation of transferase activity; GO:0031323 regulation of cellular metabolic process; GO:0043086 negative regulation of catalytic activity; GO:0032501 multicellular organismal process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0050776 regulation of immune response; GO:0002683 negative regulation of immune system process; GO:0050865 regulation of cell activation; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0045931 positive regulation of mitotic cell cycle; GO:0080135 regulation of cellular response to stress; GO:1902532 negative regulation of intracellular signal transduction; GO:0001701 in utero embryonic development; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0048583 regulation of response to stimulus; GO:0050856 regulation of T cell receptor signaling pathway; GO:0044260 cellular macromolecule metabolic process; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0006469 negative regulation of protein kinase activity; GO:0002682 regulation of immune system process; GO:0044092 negative regulation of molecular function; GO:0006464 cellular protein modification process; GO:0019220 regulation of phosphate metabolic process; GO:0036211 protein modification process; GO:0050868 negative regulation of T cell activation; GO:0048856 anatomical structure development; GO:0043549 regulation of kinase activity; GO:0045859 regulation of protein kinase activity; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0007346 regulation of mitotic cell cycle; GO:0007162 negative regulation of cell adhesion; GO:0043407 negative regulation of MAP kinase activity; GO:0051250 negative regulation of lymphocyte activation; GO:0060255 regulation of macromolecule metabolic process; GO:0043405 regulation of MAP kinase activity; GO:0031399 regulation of protein modification process; GO:0050860 negative regulation of T cell receptor signaling pathway; GO:0044267 cellular protein metabolic process; GO:0022408 negative regulation of cell-cell adhesion; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0050866 negative regulation of cell activation; GO:0050854 regulation of antigen receptor-mediated signaling pathway; GO:0070372 regulation of ERK1 and ERK2 cascade; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0043408 regulation of MAPK cascade; GO:0042326 negative regulation of phosphorylation; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:0070373 negative regulation of ERK1 and ERK2 cascade; GO:0051338 regulation of transferase activity; GO:0001933 negative regulation of protein phosphorylation; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0009966 regulation of signal transduction; GO:0045787 positive regulation of cell cycle; GO:0035335 peptidyl-tyrosine dephosphorylation; GO:1902531 regulation of intracellular signal transduction; GO:0009792 embryo development ending in birth or egg hatching; GO:0001932 regulation of protein phosphorylation; GO:0048585 negative regulation of response to stimulus; GO:0044238 primary metabolic process; GO:0006470 protein dephosphorylation; GO:0048518 positive regulation of biological process; GO:0016311 dephosphorylation; GO:0009892 negative regulation of metabolic process; GO:0030155 regulation of cell adhesion; GO:0022407 regulation of cell-cell adhesion; GO:0006793 phosphorus metabolic process; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0010563 negative regulation of phosphorus metabolic process; GO:0043409 negative regulation of MAPK cascade; GO:0051248 negative regulation of protein metabolic process; GO:0043412 macromolecule modification; GO:0045936 negative regulation of phosphate metabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0001772 immunological synapse; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0004725 protein tyrosine phosphatase activity; GO:0003824 catalytic activity; GO:0042578 phosphoric ester hydrolase activity; GO:0005488 binding; GO:0033549 MAP kinase phosphatase activity; GO:0016791 phosphatase activity; GO:0019901 protein kinase binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0008138 protein tyrosine/serine/threonine phosphatase activity; GO:0004721 phosphoprotein phosphatase activity; GO:0019900 kinase binding; GO:0019899 enzyme binding; ","K17614","DUSP3; dual specificity phosphatase 3 [EC:3.1.3.16 3.1.3.48]","hsa04010 MAPK signaling pathway - Homo sapiens (human); ","IPR029021; IPR000387; IPR000340; IPR020422; ","\"Protein-tyrosine phosphatase-like; Tyrosine specific protein phosphatases domain; Dual specificity phosphatase, catalytic domain; Dual specificity protein phosphatase domain; \"\r"]
["P51570","Galactokinase OS=Homo sapiens OX=9606 GN=GALK1","GALK1",42.272,43.273,21.9,7,8,7,1.015,0.961,1.007,0.967,0.963,1.09,1.012,0.816,"nucleus\r","GO:0046365 monosaccharide catabolic process; GO:0006757 ATP generation from ADP; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0006165 nucleoside diphosphate phosphorylation; GO:0046031 ADP metabolic process; GO:0019362 pyridine nucleotide metabolic process; GO:0006096 glycolytic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0006066 alcohol metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009185 ribonucleoside diphosphate metabolic process; GO:0046939 nucleotide phosphorylation; GO:0009135 purine nucleoside diphosphate metabolic process; GO:0072524 pyridine-containing compound metabolic process; GO:0044237 cellular metabolic process; GO:0061615 glycolytic process through fructose-6-phosphate; GO:0006796 phosphate-containing compound metabolic process; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0044262 cellular carbohydrate metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0009179 purine ribonucleoside diphosphate metabolic process; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0019402 galactitol metabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0061620 glycolytic process through glucose-6-phosphate; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0006059 hexitol metabolic process; GO:0006732 coenzyme metabolic process; GO:0005975 carbohydrate metabolic process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0016052 carbohydrate catabolic process; GO:0051186 cofactor metabolic process; GO:1901575 organic substance catabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0019388 galactose catabolic process; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0006082 organic acid metabolic process; GO:0043436 oxoacid metabolic process; GO:0016310 phosphorylation; GO:1901615 organic hydroxy compound metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0046496 nicotinamide nucleotide metabolic process; GO:0009259 ribonucleotide metabolic process; GO:0071704 organic substance metabolic process; GO:0006090 pyruvate metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0046835 carbohydrate phosphorylation; GO:0005996 monosaccharide metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0009119 ribonucleoside metabolic process; GO:0009987 cellular process; GO:0009132 nucleoside diphosphate metabolic process; GO:0046034 ATP metabolic process; GO:0019400 alditol metabolic process; GO:0044724 single-organism carbohydrate catabolic process; GO:0061623 glycolytic process from galactose; GO:0044712 single-organism catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044282 small molecule catabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0019751 polyol metabolic process; GO:0006163 purine nucleotide metabolic process; GO:0046128 purine ribonucleoside metabolic process; GO:0061622 glycolytic process through glucose-1-phosphate; GO:0006793 phosphorus metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0019320 hexose catabolic process; GO:0009056 catabolic process; GO:0006012 galactose metabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0019318 hexose metabolic process; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0048029 monosaccharide binding; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0019200 carbohydrate kinase activity; GO:0097367 carbohydrate derivative binding; GO:0016301 kinase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005534 galactose binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0030246 carbohydrate binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0016740 transferase activity; GO:0004335 galactokinase activity; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K00849","galK; galactokinase [EC:2.7.1.6]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00052 Galactose metabolism - Homo sapiens (human); hsa00520 Amino sugar and nucleotide sugar metabolism - Homo sapiens (human); ","IPR019539; IPR020568; IPR006204; IPR014721; IPR013750; ","\"Galactokinase galactose-binding domain; Ribosomal protein S5 domain 2-type fold; GHMP kinase N-terminal domain; Ribosomal protein S5 domain 2-type fold, subgroup; GHMP kinase, C-terminal domain; \"\r"]
["P51580","Thiopurine S-methyltransferase OS=Homo sapiens OX=9606 GN=TPMT","TPMT",28.18,5.8785,11.8,4,5,4,0.938,0.998,0.863,1.125,1.028,1.052,1.145,0.0526,"cytoplasm\r","GO:0008152 metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:0009987 cellular process; GO:0044237 cellular metabolic process; GO:0032259 methylation; GO:0071704 organic substance metabolic process; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0008757 S-adenosylmethionine-dependent methyltransferase activity; GO:0016741 transferase activity, transferring one-carbon groups; GO:0008168 methyltransferase activity; GO:0008119 thiopurine S-methyltransferase activity; GO:0003824 catalytic activity; GO:0016740 transferase activity; GO:0008172 S-methyltransferase activity; ","K00569","TPMT; thiopurine S-methyltransferase [EC:2.1.1.67]","hsa00983 Drug metabolism - other enzymes - Homo sapiens (human); ","IPR029063; ","S-adenosyl-L-methionine-dependent methyltransferase; \r"]
["P51608","Methyl-CpG-binding protein 2 OS=Homo sapiens OX=9606 GN=MECP2","MECP2",52.44,31.053,17.7,7,7,7,1.094,1.077,1.018,0.998,0.899,0.943,0.891,0.0355,"nucleus\r",{"$cut":{"chars":17983,"head":"GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0021700 developmental maturation; GO:0006020 inositol metabolic process; GO:0006066 alcohol metabolic process; GO:0043523 regulation of neuron apoptotic process; GO:0009891 positive regulation of biosynthetic process; GO:0044255 cellular lipid metabolic process; GO:1900112 regulation of histone H3-K9 trimethylation; GO:0044237 cellular metabolic process; GO:0050432 catecholamine secretion; GO:1905269 positive regulation of chromatin organization; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0044057 regulation of system process; GO:0019693 ribose phosphate metabolic process; GO:0051147 regulation of muscle cell differentiation; GO:0044106 cellular amine metabolic process; GO:0051716 cellular response to stimulus; GO:0001976 neurological system process involved in regulation of systemic arterial blood pressure; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0008202 steroid metabolic process; GO:0044763 single-organism cellular process; GO:0005975 carbohydrate metabolic process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0007267 cell-cell signaling; GO:0007612 learning; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0031060 regulation of histone methylation; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation; GO:0043576 regulation of respiratory gaseous exchange; GO:0060548 negative regulation of cell death; GO:0043436 oxoacid metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0016310 phosphorylation; GO:0044707 single-multicellular organism process; GO:0006349 regulation of gene expression by genetic imprinting; GO:0009259 ribonucleotide metabolic process; GO:0016570 histone modification; GO:0006541 glutamine metabolic process; GO:0033555 multicellular organismal response to stress; GO:0009791 post-embryonic development; GO:0048519 negative regulation of biological process; GO:0045892 negative regulation of transcription, DNA-templated; GO:0001964 startle response; GO:0043524 negative regulation of neuron apoptotic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0070482 response to oxygen levels; GO:0061061 muscle structure development; GO:1902680 positive regulation of RNA biosynthetic process; GO:0099565 chemical synaptic transmission, postsynaptic; GO:0030534 adult behavior; GO:0009308 amine metabolic process; GO:0030902 hindbrain development; GO:1901215 negative regulation of neuron death; GO:0009416 response to light stimulus; GO:0006950 response to stress; GO:0050804 modulation of synaptic transmission; GO:0051960 regulation of nervous system development; GO:0007416 synapse assembly; GO:0009141 nucleoside triphosphate metabolic process; GO:0050808 synapse organization; GO:1901576 organic substance biosynthetic process; GO:0019751 polyol metabolic process; GO:0006163 purine nucleotide metabolic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0009890 negative regulation of biosynthetic process; GO:2001251 negative regulation of chromosome organization; GO:0099536 synaptic signaling; GO:0043414 macromolecule methylation; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0019637 organophosphate metabolic process; GO:0006644 phospholipid metabolic process; GO:0043412 macromolecule modification; GO:0007268 chemical synaptic transmission; GO:0008284 positive regulation of cell proliferation; GO:0051093 negative regulation of developmental process; GO:0046470 phosphatidylcholine metaboli"}},"GO:0043229 intracellular organelle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0000792 heterochromatin; GO:0045202 synapse; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0098794 postsynapse; GO:0000785 chromatin; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0043227 membrane-bounded organelle; GO:0044456 synapse part; GO:0044444 cytoplasmic part; ","GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding; GO:1901265 nucleoside phosphate binding; GO:0047485 protein N-terminus binding; GO:0003690 double-stranded DNA binding; GO:0008327 methyl-CpG binding; GO:0005515 protein binding; GO:0003682 chromatin binding; GO:0003700 transcription factor activity, sequence-specific DNA binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0035197 siRNA binding; GO:0003729 mRNA binding; GO:0042826 histone deacetylase binding; GO:0005488 binding; GO:0001071 nucleic acid binding transcription factor activity; GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0003723 RNA binding; GO:0003677 DNA binding; GO:0003714 transcription corepressor activity; GO:0010385 double-stranded methylated DNA binding; GO:0000166 nucleotide binding; GO:0043565 sequence-specific DNA binding; GO:0003712 transcription cofactor activity; GO:0003676 nucleic acid binding; GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding; GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding; GO:0019904 protein domain specific binding; GO:0000988 transcription factor activity, protein binding; GO:0019899 enzyme binding; GO:0008134 transcription factor binding; GO:0036094 small molecule binding; ","K11588",null,null,"IPR016177; IPR001739; ","DNA-binding domain; Methyl-CpG DNA binding; \r"]
["P51659","Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4","HSD17B4",79.685,107.34,31.5,17,24,17,0.975,0.901,0.908,1.014,1.075,1.048,1.127,0.0168,"cytoplasm\r","GO:0001649 osteoblast differentiation; GO:0065008 regulation of biological quality; GO:0016053 organic acid biosynthetic process; GO:0022414 reproductive process; GO:0008584 male gonad development; GO:0035337 fatty-acyl-CoA metabolic process; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0008610 lipid biosynthetic process; GO:0008209 androgen metabolic process; GO:0008152 metabolic process; GO:0030258 lipid modification; GO:0044702 single organism reproductive process; GO:0032787 monocarboxylic acid metabolic process; GO:0008210 estrogen metabolic process; GO:0008206 bile acid metabolic process; GO:0006629 lipid metabolic process; GO:0006790 sulfur compound metabolic process; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0019395 fatty acid oxidation; GO:0003006 developmental process involved in reproduction; GO:0002064 epithelial cell development; GO:0042445 hormone metabolic process; GO:0009888 tissue development; GO:0001503 ossification; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0048608 reproductive structure development; GO:0008202 steroid metabolic process; GO:0044763 single-organism cellular process; GO:0060008 Sertoli cell differentiation; GO:1901360 organic cyclic compound metabolic process; GO:0072329 monocarboxylic acid catabolic process; GO:1901617 organic hydroxy compound biosynthetic process; GO:0006732 coenzyme metabolic process; GO:0032501 multicellular organismal process; GO:0034754 cellular hormone metabolic process; GO:0051186 cofactor metabolic process; GO:0046395 carboxylic acid catabolic process; GO:1901575 organic substance catabolic process; GO:0046394 carboxylic acid biosynthetic process; GO:0048513 animal organ development; GO:0044710 single-organism metabolic process; GO:0010817 regulation of hormone levels; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:0009062 fatty acid catabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0043436 oxoacid metabolic process; GO:0030855 epithelial cell differentiation; GO:0033559 unsaturated fatty acid metabolic process; GO:0000003 reproduction; GO:0044707 single-multicellular organism process; GO:0034440 lipid oxidation; GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase; GO:1901615 organic hydroxy compound metabolic process; GO:0046661 male sex differentiation; GO:0008406 gonad development; GO:0036109 alpha-linolenic acid metabolic process; GO:0048468 cell development; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0007548 sex differentiation; GO:0044248 cellular catabolic process; GO:0007275 multicellular organism development; GO:0061458 reproductive system development; GO:0009987 cellular process; GO:0045137 development of primary sexual characteristics; GO:0016042 lipid catabolic process; GO:0044711 single-organism biosynthetic process; GO:0048731 system development; GO:0044712 single-organism catabolic process; GO:0035383 thioester metabolic process; GO:0006635 fatty acid beta-oxidation; GO:0044282 small molecule catabolic process; GO:0006631 fatty acid metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0006637 acyl-CoA metabolic process; GO:0006694 steroid biosynthetic process; GO:0036112 medium-chain fatty-acyl-CoA metabolic process; GO:0000038 very long-chain fatty acid metabolic process; GO:0036111 very long-chain fatty-acyl-CoA metabolic process; GO:0006793 phosphorus metabolic process; GO:0060009 Sertoli cell development; GO:0044767 single-organism developmental process; GO:0001676 long-chain fatty acid metabolic process; GO:0044283 small molecule biosynthetic process; GO:0019752 carboxylic acid metabolic process; GO:0016054 organic acid catabolic process; GO:0044242 cellular lipid catabolic process; GO:0046546 development of primary male sexual characteristics; GO:0072330 monocarboxylic acid biosynthetic process; GO:0009056 catabolic process; GO:0006699 bile acid biosynthetic process; GO:0065007 biological regulation; ","GO:0031903 microbody membrane; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0098588 bounding membrane of organelle; GO:0044439 peroxisomal part; GO:0031090 organelle membrane; GO:0005777 peroxisome; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0044438 microbody part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0005778 peroxisomal membrane; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031907 microbody lumen; GO:0070013 intracellular organelle lumen; GO:0005782 peroxisomal matrix; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0042579 microbody; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; ","GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; GO:0005102 receptor binding; GO:0046983 protein dimerization activity; GO:0016829 lyase activity; GO:0016836 hydro-lyase activity; GO:0005515 protein binding; GO:0016835 carbon-oxygen lyase activity; GO:0016491 oxidoreductase activity; GO:0016229 steroid dehydrogenase activity; GO:0016614 oxidoreductase activity, acting on CH-OH group of donors; GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; GO:0016853 isomerase activity; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0042803 protein homodimerization activity; GO:0033989 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity; GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity; GO:0016508 long-chain-enoyl-CoA hydratase activity; GO:0044594 17-beta-hydroxysteroid dehydrogenase (NAD+) activity; ","K12405","HSD17B4; 3-hydroxyacyl-CoA dehydrogenase / 3a,7a,12a-trihydroxy-5b-cholest-24-enoyl-CoA hydratase / enoyl-CoA hydratase 2 [EC:1.1.1.35 4.2.1.107 4.2.1.119]","hsa00120 Primary bile acid biosynthesis - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa04146 Peroxisome - Homo sapiens (human); ","IPR016040; IPR003033; IPR029069; IPR002539; ","NAD(P)-binding domain; SCP2 sterol-binding domain; HotDog domain; MaoC-like domain; \r"]
["P51665","26S proteasome non-ATPase regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMD7","PSMD7",37.025,44.175,24.1,6,10,6,0.876,0.907,0.872,1.139,1.139,1.11,1.276,8.31e-05,"endoplasmic reticulum\r","GO:0044700 single organism signaling; GO:0010608 posttranscriptional regulation of gene expression; GO:0051443 positive regulation of ubiquitin-protein transferase activity; GO:0031347 regulation of defense response; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:1903364 positive regulation of cellular protein catabolic process; GO:0008152 metabolic process; GO:0044093 positive regulation of molecular function; GO:0090263 positive regulation of canonical Wnt signaling pathway; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0016055 Wnt signaling pathway; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0006521 regulation of cellular amino acid metabolic process; GO:0080090 regulation of primary metabolic process; GO:0010972 negative regulation of G2/M transition of mitotic cell cycle; GO:0044763 single-organism cellular process; GO:0060828 regulation of canonical Wnt signaling pathway; GO:0043086 negative regulation of catalytic activity; GO:0033209 tumor necrosis factor-mediated signaling pathway; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0000165 MAPK cascade; GO:1901575 organic substance catabolic process; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0007267 cell-cell signaling; GO:0002223 stimulatory C-type lectin receptor signaling pathway; GO:0030163 protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0060071 Wnt signaling pathway, planar cell polarity pathway; GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0016310 phosphorylation; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0043487 regulation of RNA stability; GO:0000209 protein polyubiquitination; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0009889 regulation of biosynthetic process; GO:0009896 positive regulation of catabolic process; GO:0043620 regulation of DNA-templated transcription in response to stress; GO:0070482 response to oxygen levels; GO:0044248 cellular catabolic process; GO:0042176 regulation of protein catabolic process; GO:0038093 Fc receptor signaling pathway; GO:0050778 positive regulation of immune response; GO:0023014 signal transduction by protein phosphorylation; GO:0006950 response to stress; GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; GO:0016567 protein ubiquitination; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress; GO:0002263 cell activation involved in immune response; GO:1903321 negative regulation of protein modification by small protein conjugation or removal; GO:0045055 regulated exocytosis; GO:0031398 positive regulation of protein ubiquitination; GO:0032446 protein modification by small protein conjugation; GO:0031325 positive regulation of cellular metabolic process; GO:0030177 positive regulation of Wnt signaling pathway; GO:1904668 positive regulation of ubiquitin protein ligase activity; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0006955 immune response; GO:0043412 macromolecule modification; GO:0070646 protein modification by small protein removal; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0031331 positive regulation of cellular catabolic process; GO:0044699 single-organism process; GO:0031400 negative regulation of protein modification process; GO:0006796 phosphate-containing compound metabolic process; GO:0031396 regulation of protein ubiquitination; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0045930 negative regulation of mitotic cell cycle; GO:0009893 positive regulation of metabolic process; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0034612 response to tumor necrosis factor; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0051726 regulation of cell cycle; GO:0034097 response to cytokine; GO:0031326 regulation of cellular biosynthetic process; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0198738 cell-cell signaling by wnt; GO:0010565 regulation of cellular ketone metabolic process; GO:0032940 secretion by cell; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0036211 protein modification process; GO:0090175 regulation of establishment of planar polarity; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0045786 negative regulation of cell cycle; GO:0044257 cellular protein catabolic process; GO:1901988 negative regulation of cell cycle phase transition; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0010498 proteasomal protein catabolic process; GO:0071704 organic substance metabolic process; GO:0045862 positive regulation of proteolysis; GO:2000027 regulation of organ morphogenesis; GO:0006468 protein phosphorylation; GO:0023056 positive regulation of signaling; GO:0001666 response to hypoxia; GO:0002757 immune response-activating signal transduction; GO:0010647 positive regulation of cell communication; GO:0071453 cellular response to oxygen levels; GO:0019221 cytokine-mediated signaling pathway; GO:0031397 negative regulation of protein ubiquitination; GO:0006355 regulation of transcription, DNA-templated; GO:0035556 intracellular signal transduction; GO:0019941 modification-dependent protein catabolic process; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia; GO:1902749 regulation of cell cycle G2/M phase transition; GO:0043488 regulation of mRNA stability; GO:0043085 positive regulation of catalytic activity; GO:0002366 leukocyte activation involved in immune response; GO:0019882 antigen processing and presentation; GO:0042119 neutrophil activation; GO:0050852 T cell receptor signaling pathway; GO:0002684 positive regulation of immune system process; GO:0038095 Fc-epsilon receptor signaling pathway; GO:0051248 negative regulation of protein metabolic process; GO:0022402 cell cycle process; GO:1902750 negative regulation of cell cycle G2/M phase transition; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0045321 leukocyte activation; GO:0002220 innate immune response activating cell surface receptor signaling pathway; GO:0007166 cell surface receptor signaling pathway; GO:0071345 cellular response to cytokine stimulus; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0051347 positive regulation of transferase activity; GO:1903362 regulation of cellular protein catabolic process; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0002443 leukocyte mediated immunity; GO:0002758 innate immune response-activating signal transduction; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0031323 regulation of cellular metabolic process; GO:2000058 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0010948 negative regulation of cell cycle process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0002682 regulation of immune system process; GO:0031145 anaphase-promoting complex-dependent catabolic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0007346 regulation of mitotic cell cycle; GO:0002283 neutrophil activation involved in immune response; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:0051239 regulation of multicellular organismal process; GO:0031349 positive regulation of defense response; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:1901987 regulation of cell cycle phase transition; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0010389 regulation of G2/M transition of mitotic cell cycle; GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; GO:0009966 regulation of signal transduction; GO:0038061 NIK/NF-kappaB signaling; GO:0071456 cellular response to hypoxia; GO:0002253 activation of immune response; GO:0016192 vesicle-mediated transport; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1904666 regulation of ubiquitin protein ligase activity; GO:0055085 transmembrane transport; GO:0051247 positive regulation of protein metabolic process; GO:0051438 regulation of ubiquitin-protein transferase activity; GO:0030111 regulation of Wnt signaling pathway; GO:0006793 phosphorus metabolic process; GO:0001775 cell activation; GO:0036293 response to decreased oxygen levels; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process; GO:0006887 exocytosis; GO:0051444 negative regulation of ubiquitin-protein transferase activity; GO:0090090 negative regulation of canonical Wnt signaling pathway; GO:0051234 establishment of localization; GO:0035567 non-canonical Wnt signaling pathway; GO:1905330 regulation of morphogenesis of an epithelium; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:1901991 negative regulation of mitotic cell cycle phase transition; GO:0045088 regulation of innate immune response; GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I; GO:0070887 cellular response to chemical stimulus; GO:0002274 myeloid leukocyte activation; GO:0050851 antigen receptor-mediated signaling pathway; GO:0010468 regulation of gene expression; GO:0030178 negative regulation of Wnt signaling pathway; GO:0048002 antigen processing and presentation of peptide antigen; GO:0002446 neutrophil mediated immunity; GO:0048522 positive regulation of cellular process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0051348 negative regulation of transferase activity; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0019222 regulation of metabolic process; GO:0043299 leukocyte degranulation; GO:2000026 regulation of multicellular organismal development; GO:0002218 activation of innate immune response; GO:1904667 negative regulation of ubiquitin protein ligase activity; GO:0002252 immune effector process; GO:0071356 cellular response to tumor necrosis factor; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0016579 protein deubiquitination; GO:0050896 response to stimulus; GO:1903322 positive regulation of protein modification by small protein conjugation or removal; GO:0006508 proteolysis; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:0033238 regulation of cellular amine metabolic process; GO:0043632 modification-dependent macromolecule catabolic process; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0045089 positive regulation of innate immune response; GO:0031401 positive regulation of protein modification process; GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0051246 regulation of protein metabolic process; GO:0009057 macromolecule catabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0009967 positive regulation of signal transduction; GO:0045732 positive regulation of protein catabolic process; GO:0036294 cellular response to decreased oxygen levels; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0034774 secretory granule lumen; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005838 proteasome regulatory particle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:1905369 endopeptidase complex; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:1902494 catalytic complex; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0022624 proteasome accessory complex; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:1905368 peptidase complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0000502 proteasome complex; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0042802 identical protein binding; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0046983 protein dimerization activity; ","K03038","PSMD7; 26S proteasome regulatory subunit N8","hsa03050 Proteasome - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); ","IPR000555; IPR024969; ","\"JAB1/MPN/MOV34 metalloenzyme domain; Rpn11/EIF3F, C-terminal; \"\r"]
["P51808","Dynein light chain Tctex-type 3 OS=Homo sapiens OX=9606 GN=DYNLT3","DYNLT3",13.062,11.18,14.7,1,1,1,0.928,1.033,0.923,1.112,1.04,0.973,1.084,0.206,"extracellular\r","GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0000278 mitotic cell cycle; GO:0007346 regulation of mitotic cell cycle; GO:0007067 mitotic nuclear division; GO:0048285 organelle fission; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:1903047 mitotic cell cycle process; GO:0051234 establishment of localization; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0006996 organelle organization; GO:0000280 nuclear division; GO:0051301 cell division; GO:0022402 cell cycle process; GO:0051179 localization; GO:0009987 cellular process; GO:0051726 regulation of cell cycle; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0005874 microtubule; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0005623 cell; GO:0099080 supramolecular complex; GO:0000777 condensed chromosome kinetochore; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0000793 condensed chromosome; GO:0005856 cytoskeleton; GO:1902494 catalytic complex; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0043227 membrane-bounded organelle; GO:0000776 kinetochore; GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0000779 condensed chromosome, centromeric region; GO:0044446 intracellular organelle part; GO:0030286 dynein complex; GO:0005875 microtubule associated complex; GO:0005868 cytoplasmic dynein complex; GO:0099081 supramolecular polymer; GO:0043226 organelle; GO:0098687 chromosomal region; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0000775 chromosome, centromeric region; GO:0043234 protein complex; ","GO:0042802 identical protein binding; GO:0003774 motor activity; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017111 nucleoside-triphosphatase activity; ","K10420"]
["P51828","Adenylate cyclase type 7 OS=Homo sapiens OX=9606 GN=ADCY7","ADCY7",120.31,-2,0.9,1,1,1,0.941,0.792,0.85,1.15,1.107,1.151,1.319,5.64E-3,"plasma membrane\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0051349 positive regulation of lyase activity; GO:0032270 positive regulation of cellular protein metabolic process; GO:0022414 reproductive process; GO:0009891 positive regulation of biosynthetic process; GO:0044237 cellular metabolic process; GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; GO:0046390 ribose phosphate biosynthetic process; GO:0008152 metabolic process; GO:0030810 positive regulation of nucleotide biosynthetic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0044093 positive regulation of molecular function; GO:0044706 multi-multicellular organism process; GO:0044702 single organism reproductive process; GO:0019693 ribose phosphate metabolic process; GO:0009719 response to endogenous stimulus; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0051347 positive regulation of transferase activity; GO:1901652 response to peptide; GO:1900373 positive regulation of purine nucleotide biosynthetic process; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0072521 purine-containing compound metabolic process; GO:0097306 cellular response to alcohol; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway; GO:0051339 regulation of lyase activity; GO:0090407 organophosphate biosynthetic process; GO:0031279 regulation of cyclase activity; GO:0010243 response to organonitrogen compound; GO:0030104 water homeostasis; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:1901698 response to nitrogen compound; GO:0010604 positive regulation of macromolecule metabolic process; GO:0045981 positive regulation of nucleotide metabolic process; GO:0006164 purine nucleotide biosynthetic process; GO:0048609 multicellular organismal reproductive process; GO:1901362 organic cyclic compound biosynthetic process; GO:0006140 regulation of nucleotide metabolic process; GO:0000003 reproduction; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0060135 maternal process involved in female pregnancy; GO:0009259 ribonucleotide metabolic process; GO:0030801 positive regulation of cyclic nucleotide metabolic process; GO:0031399 regulation of protein modification process; GO:1901700 response to oxygen-containing compound; GO:0009187 cyclic nucleotide metabolic process; GO:0007565 female pregnancy; GO:0032147 activation of protein kinase activity; GO:0045761 regulation of adenylate cyclase activity; GO:0046483 heterocycle metabolic process; GO:0046058 cAMP metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0051338 regulation of transferase activity; GO:0006182 cGMP biosynthetic process; GO:0030817 regulation of cAMP biosynthetic process; GO:1901135 carbohydrate derivative metabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034199 activation of protein kinase A activity; GO:0048878 chemical homeostasis; GO:0044711 single-organism biosynthetic process; GO:0003014 renal system process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0097305 response to alcohol; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0030799 regulation of cyclic nucleotide metabolic process; GO:0006163 purine nucleotide metabolic process; GO:0007186 G-protein coupled receptor signaling pathway; GO:0051247 positive regulation of protein metabolic process; GO:0006793 phosphorus metabolic process; GO:0050891 multicellular organismal water homeostasis; GO:0031325 positive regulation of cellular metabolic process; GO:0009260 ribonucleotide biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0033762 response to glucagon; GO:0052652 cyclic purine nucleotide metabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:1901564 organonitrogen compound metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0048871 multicellular organismal homeostasis; GO:0030819 positive regulation of cAMP biosynthetic process; GO:0006796 phosphate-containing compound metabolic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:1901653 cellular response to peptide; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0030814 regulation of cAMP metabolic process; GO:0033674 positive regulation of kinase activity; GO:0070887 cellular response to chemical stimulus; GO:0003091 renal water homeostasis; GO:0030808 regulation of nucleotide biosynthetic process; GO:0045937 positive regulation of phosphate metabolic process; GO:0030802 regulation of cyclic nucleotide biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0030816 positive regulation of cAMP metabolic process; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway; GO:0023052 signaling; GO:0071417 cellular response to organonitrogen compound; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0043434 response to peptide hormone; GO:1901699 cellular response to nitrogen compound; GO:0072522 purine-containing compound biosynthetic process; GO:1900371 regulation of purine nucleotide biosynthetic process; GO:0032870 cellular response to hormone stimulus; GO:0045762 positive regulation of adenylate cyclase activity; GO:0006171 cAMP biosynthetic process; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0030804 positive regulation of cyclic nucleotide biosynthetic process; GO:0043549 regulation of kinase activity; GO:0045859 regulation of protein kinase activity; GO:0009165 nucleotide biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0071310 cellular response to organic substance; GO:0045471 response to ethanol; GO:1900544 positive regulation of purine nucleotide metabolic process; GO:0050896 response to stimulus; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0071361 cellular response to ethanol; GO:0042592 homeostatic process; GO:0071377 cellular response to glucagon stimulus; GO:0009190 cyclic nucleotide biosynthetic process; GO:0071375 cellular response to peptide hormone stimulus; GO:0034641 cellular nitrogen compound metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0003008 system process; GO:0050878 regulation of body fluid levels; GO:0035556 intracellular signal transduction; GO:0001932 regulation of protein phosphorylation; GO:0031401 positive regulation of protein modification process; GO:0006807 nitrogen compound metabolic process; GO:0045860 positive regulation of protein kinase activity; GO:0001934 positive regulation of protein phosphorylation; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0043085 positive regulation of catalytic activity; GO:1900542 regulation of purine nucleotide metabolic process; GO:0032504 multicellular organism reproduction; GO:1901701 cellular response to oxygen-containing compound; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0009152 purine ribonucleotide biosynthetic process; GO:0051246 regulation of protein metabolic process; GO:0071495 cellular response to endogenous stimulus; GO:0031281 positive regulation of cyclase activity; GO:0044703 multi-organism reproductive process; GO:0007190 activation of adenylate cyclase activity; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0009725 response to hormone; GO:0046068 cGMP metabolic process; GO:0065007 biological regulation; GO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; ","GO:0016020 membrane; GO:0071944 cell periphery; GO:0008074 guanylate cyclase complex, soluble; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0044445 cytosolic part; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0005524 ATP binding; GO:0009975 cyclase activity; GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016829 lyase activity; GO:0004016 adenylate cyclase activity; GO:0000166 nucleotide binding; GO:0004383 guanylate cyclase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0016849 phosphorus-oxygen lyase activity; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K08047","ADCY7; adenylate cyclase 7 [EC:4.6.1.1]","hsa04072 Phospholipase D signaling pathway - Homo sapiens (human); hsa04015 Rap1 signaling pathway - Homo sapiens (human); hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human); hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human); hsa05166 HTLV-I infection - Homo sapiens (human); hsa04976 Bile secretion - Homo sapiens (human); hsa04911 Insulin secretion - Homo sapiens (human); hsa04970 Salivary secretion - Homo sapiens (human); hsa04724 Glutamatergic synapse - Homo sapiens (human); hsa04114 Oocyte meiosis - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa04934 Cushing's syndrome - Homo sapiens (human); hsa04211 Longevity regulating pathway - Homo sapiens (human); hsa04611 Platelet activation - Homo sapiens (human); hsa00230 Purine metabolism - Homo sapiens (human); hsa01522 Endocrine resistance - Homo sapiens (human); hsa04927 Cortisol synthesis and secretion - Homo sapiens (human); hsa04971 Gastric acid secretion - Homo sapiens (human); hsa04914 Progesterone-mediated oocyte maturation - Homo sapiens (human); hsa04915 Estrogen signaling pathway - Homo sapiens (human); hsa05032 Morphine addiction - Homo sapiens (human); hsa04725 Cholinergic synapse - Homo sapiens (human); hsa04921 Oxytocin signaling pathway - Homo sapiens (human); hsa04371 Apelin signaling pathway - Homo sapiens (human); hsa04916 Melanogenesis - Homo sapiens (human); hsa04020 Calcium signaling pathway - Homo sapiens (human); hsa04270 Vascular smooth muscle contraction - Homo sapiens (human); hsa04923 Regulation of lipolysis in adipocytes - Homo sapiens (human); hsa04024 cAMP signaling pathway - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa04750 Inflammatory mediator regulation of TRP channels - Homo sapiens (human); hsa04213 Longevity regulating pathway - multiple species - Homo sapiens (human); hsa04062 Chemokine signaling pathway - Homo sapiens (human); hsa04925 Aldosterone synthesis and secretion - Homo sapiens (human); hsa05414 Dilated cardiomyopathy (DCM) - Homo sapiens (human); hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human); hsa04913 Ovarian steroidogenesis - Homo sapiens (human); hsa04540 Gap junction - Homo sapiens (human); hsa04972 Pancreatic secretion - Homo sapiens (human); hsa04912 GnRH signaling pathway - Homo sapiens (human); hsa04727 GABAergic synapse - Homo sapiens (human); hsa04918 Thyroid hormone synthesis - Homo sapiens (human); hsa04926 Relaxin signaling pathway - Homo sapiens (human); hsa04928 Parathyroid hormone synthesis, secretion and action - Homo sapiens (human); hsa04713 Circadian entrainment - Homo sapiens (human); ","IPR009398; IPR029787; IPR032628; IPR001054; ","\"Adenylate cyclase, conserved domain; Nucleotide cyclase; Adenylate cyclase, N-terminal; Adenylyl cyclase class-3/4/guanylyl cyclase; \"\r"]
["P51884","Lumican OS=Homo sapiens OX=9606 GN=LUM","LUM",38.429,179.9,37.6,12,65,9,1.09,1.055,1.052,0.933,0.963,0.942,0.888,0.00128,"extracellular\r","GO:0030199 collagen fibril organization; GO:0007601 visual perception; GO:0051216 cartilage development; GO:0006024 glycosaminoglycan biosynthetic process; GO:0006026 aminoglycan catabolic process; GO:0009891 positive regulation of biosynthetic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0042340 keratan sulfate catabolic process; GO:0044237 cellular metabolic process; GO:0044272 sulfur compound biosynthetic process; GO:0050877 neurological system process; GO:0032914 positive regulation of transforming growth factor beta1 production; GO:0030203 glycosaminoglycan metabolic process; GO:0042339 keratan sulfate metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0009893 positive regulation of metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0070848 response to growth factor; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0043170 macromolecule metabolic process; GO:0061448 connective tissue development; GO:0030198 extracellular matrix organization; GO:0006790 sulfur compound metabolic process; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0014070 response to organic cyclic compound; GO:0007600 sensory perception; GO:0071822 protein complex subunit organization; GO:0009888 tissue development; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0006027 glycosaminoglycan catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:1901575 organic substance catabolic process; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0044710 single-organism metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0032908 regulation of transforming growth factor beta1 production; GO:0044273 sulfur compound catabolic process; GO:0006082 organic acid metabolic process; GO:0097435 supramolecular fiber organization; GO:0048856 anatomical structure development; GO:0043436 oxoacid metabolic process; GO:0001501 skeletal system development; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0060255 regulation of macromolecule metabolic process; GO:0001819 positive regulation of cytokine production; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:0071704 organic substance metabolic process; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0043062 extracellular structure organization; GO:0051171 regulation of nitrogen compound metabolic process; GO:0044248 cellular catabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0007275 multicellular organism development; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006022 aminoglycan metabolic process; GO:0051254 positive regulation of RNA metabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0006023 aminoglycan biosynthetic process; GO:0003008 system process; GO:1903510 mucopolysaccharide metabolic process; GO:0071634 regulation of transforming growth factor beta production; GO:0044711 single-organism biosynthetic process; GO:0048731 system development; GO:0044712 single-organism catabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:1901136 carbohydrate derivative catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0050953 sensory perception of light stimulus; GO:0010033 response to organic substance; GO:0051252 regulation of RNA metabolic process; GO:1901576 organic substance biosynthetic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0043933 macromolecular complex subunit organization; GO:1901565 organonitrogen compound catabolic process; GO:0044767 single-organism developmental process; GO:0031325 positive regulation of cellular metabolic process; GO:0009057 macromolecule catabolic process; GO:0018146 keratan sulfate biosynthetic process; GO:0001817 regulation of cytokine production; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0071636 positive regulation of transforming growth factor beta production; GO:0009056 catabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; GO:1901564 organonitrogen compound metabolic process; ","GO:0098643 banded collagen fibril; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0005583 fibrillar collagen trimer; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0044420 extracellular matrix component; GO:0005581 collagen trimer; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0098644 complex of collagen trimers; GO:0044446 intracellular organelle part; GO:0005796 Golgi lumen; GO:0012505 endomembrane system; GO:0043202 lysosomal lumen; GO:0005576 extracellular region; GO:0099081 supramolecular polymer; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031012 extracellular matrix; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005578 proteinaceous extracellular matrix; GO:0005794 Golgi apparatus; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005201 extracellular matrix structural constituent; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0005515 protein binding; GO:0005518 collagen binding; GO:0005198 structural molecule activity; GO:0032403 protein complex binding; ","K08122","LUM; lumican","hsa05205 Proteoglycans in cancer - Homo sapiens (human); ","IPR000372; IPR032675; ","\"Leucine-rich repeat N-terminal domain; Leucine-rich repeat domain, L domain-like; \"\r"]
["P51911","Calponin-1 OS=Homo sapiens OX=9606 GN=CNN1","CNN1",33.17,145.53,47.8,14,34,13,1.102,1.087,1.111,0.901,0.895,0.89,0.814,4.69E-6,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0031032 actomyosin structure organization; GO:0016043 cellular component organization; GO:0042127 regulation of cell proliferation; GO:0048660 regulation of smooth muscle cell proliferation; GO:0006937 regulation of muscle contraction; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0090257 regulation of muscle system process; GO:0051239 regulation of multicellular organismal process; GO:0008285 negative regulation of cell proliferation; GO:1904706 negative regulation of vascular smooth muscle cell proliferation; GO:0048662 negative regulation of smooth muscle cell proliferation; GO:1902589 single-organism organelle organization; GO:0030036 actin cytoskeleton organization; GO:0050789 regulation of biological process; GO:0006996 organelle organization; GO:0006940 regulation of smooth muscle contraction; GO:0030029 actin filament-based process; GO:0044057 regulation of system process; GO:1904705 regulation of vascular smooth muscle cell proliferation; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0005856 cytoskeleton; GO:0043226 organelle; GO:0043229 intracellular organelle; GO:0005925 focal adhesion; GO:0043232 intracellular non-membrane-bounded organelle; GO:0030054 cell junction; GO:0044464 cell part; GO:0005622 intracellular; GO:0005912 adherens junction; GO:0070161 anchoring junction; GO:0030055 cell-substrate junction; GO:0044424 intracellular part; GO:0005623 cell; GO:0005924 cell-substrate adherens junction; GO:0043228 non-membrane-bounded organelle; ","GO:0003779 actin binding; GO:0005515 protein binding; GO:0008092 cytoskeletal protein binding; GO:0005516 calmodulin binding; GO:0005488 binding; ",{"$nulls":3},"IPR001715; ","Calponin homology domain; \r"]
["P52179","Myomesin-1 OS=Homo sapiens OX=9606 GN=MYOM1","MYOM1",187.62,34.229,1.8,2,4,2,0.903,0.828,1.081,1.02,1.092,1.068,1.131,0.187,"nucleus\r","GO:0014706 striated muscle tissue development; GO:0044085 cellular component biogenesis; GO:0055001 muscle cell development; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0043010 camera-type eye development; GO:0003012 muscle system process; GO:0048869 cellular developmental process; GO:0032989 cellular component morphogenesis; GO:0044699 single-organism process; GO:0007015 actin filament organization; GO:0048468 cell development; GO:0009653 anatomical structure morphogenesis; GO:0001654 eye development; GO:0030154 cell differentiation; GO:0030036 actin cytoskeleton organization; GO:0006936 muscle contraction; GO:0022607 cellular component assembly; GO:0070925 organelle assembly; GO:0065003 macromolecular complex assembly; GO:0030239 myofibril assembly; GO:0061061 muscle structure development; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0007519 skeletal muscle tissue development; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0009987 cellular process; GO:0071688 striated muscle myosin thick filament assembly; GO:0006461 protein complex assembly; GO:0043623 cellular protein complex assembly; GO:0032502 developmental process; GO:0034622 cellular macromolecular complex assembly; GO:0031032 actomyosin structure organization; GO:0051146 striated muscle cell differentiation; GO:0071822 protein complex subunit organization; GO:0009888 tissue development; GO:0003008 system process; GO:0060537 muscle tissue development; GO:0048731 system development; GO:0010927 cellular component assembly involved in morphogenesis; GO:0044763 single-organism cellular process; GO:0006941 striated muscle contraction; GO:0031033 myosin filament organization; GO:0031034 myosin filament assembly; GO:0060538 skeletal muscle organ development; GO:0032501 multicellular organismal process; GO:0043933 macromolecular complex subunit organization; GO:1902589 single-organism organelle organization; GO:0048513 animal organ development; GO:0045214 sarcomere organization; GO:0055002 striated muscle cell development; GO:0007517 muscle organ development; GO:0044767 single-organism developmental process; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0002074 extraocular skeletal muscle development; GO:0042692 muscle cell differentiation; GO:0070271 protein complex biogenesis; GO:0007423 sensory organ development; GO:0048856 anatomical structure development; GO:0097435 supramolecular fiber organization; GO:0071840 cellular component organization or biogenesis; ","GO:0030016 myofibril; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0030018 Z disc; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0031674 I band; GO:0044422 organelle part; GO:0005863 striated muscle myosin thick filament; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0016460 myosin II complex; GO:0043292 contractile fiber; GO:0031430 M band; GO:0016459 myosin complex; GO:0032982 myosin filament; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0005859 muscle myosin complex; GO:0015629 actin cytoskeleton; GO:0036379 myofilament; GO:0099081 supramolecular polymer; GO:0043226 organelle; GO:0031672 A band; GO:0030017 sarcomere; GO:0044449 contractile fiber part; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0051015 actin filament binding; GO:0046983 protein dimerization activity; GO:0044877 macromolecular complex binding; GO:0005515 protein binding; GO:0008307 structural constituent of muscle; GO:0051371 muscle alpha-actinin binding; GO:0097493 structural molecule activity conferring elasticity; GO:0008092 cytoskeletal protein binding; GO:0042802 identical protein binding; GO:0005488 binding; GO:0042803 protein homodimerization activity; GO:0042805 actinin binding; GO:0003779 actin binding; GO:0051393 alpha-actinin binding; GO:0005198 structural molecule activity; GO:0032403 protein complex binding; ",{"$nulls":3},"IPR003598; IPR007110; IPR013783; IPR003599; IPR003961; IPR013098; ","Immunoglobulin subtype 2; Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin subtype; Fibronectin type III; Immunoglobulin I-set; \r"]
["P52306","Rap1 GTPase-GDP dissociation stimulator 1 OS=Homo sapiens OX=9606 GN=RAP1GDS1","RAP1GDS1",66.316,51.217,19.9,10,13,10,0.925,0.96,0.946,1.054,1.1,1.053,1.133,0.00228,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0003012 muscle system process; GO:0065008 regulation of biological quality; GO:0072503 cellular divalent inorganic cation homeostasis; GO:0044699 single-organism process; GO:0097746 regulation of blood vessel diameter; GO:0030036 actin cytoskeleton organization; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0044093 positive regulation of molecular function; GO:0055065 metal ion homeostasis; GO:0071822 protein complex subunit organization; GO:0050801 ion homeostasis; GO:0055074 calcium ion homeostasis; GO:0051561 positive regulation of mitochondrial calcium ion concentration; GO:0098771 inorganic ion homeostasis; GO:0044763 single-organism cellular process; GO:0019725 cellular homeostasis; GO:0031033 myosin filament organization; GO:0031034 myosin filament assembly; GO:0032501 multicellular organismal process; GO:0035296 regulation of tube diameter; GO:0006874 cellular calcium ion homeostasis; GO:1902589 single-organism organelle organization; GO:0006939 smooth muscle contraction; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0065009 regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0070271 protein complex biogenesis; GO:0003013 circulatory system process; GO:0072507 divalent inorganic cation homeostasis; GO:0016043 cellular component organization; GO:0050880 regulation of blood vessel size; GO:0030003 cellular cation homeostasis; GO:0003018 vascular process in circulatory system; GO:0055082 cellular chemical homeostasis; GO:0042592 homeostatic process; GO:0006936 muscle contraction; GO:0051345 positive regulation of hydrolase activity; GO:0055080 cation homeostasis; GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration; GO:0008015 blood circulation; GO:0014829 vascular smooth muscle contraction; GO:0035150 regulation of tube size; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0048878 chemical homeostasis; GO:0043623 cellular protein complex assembly; GO:0034622 cellular macromolecular complex assembly; GO:0003008 system process; GO:0042310 vasoconstriction; GO:0043547 positive regulation of GTPase activity; GO:0097756 negative regulation of blood vessel diameter; GO:0051560 mitochondrial calcium ion homeostasis; GO:0043085 positive regulation of catalytic activity; GO:0043933 macromolecular complex subunit organization; GO:0006873 cellular ion homeostasis; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0090066 regulation of anatomical structure size; GO:0006875 cellular metal ion homeostasis; GO:0032469 endoplasmic reticulum calcium ion homeostasis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0005783 endoplasmic reticulum; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0030234 enzyme regulator activity; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0005488 binding; GO:0030695 GTPase regulator activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0008047 enzyme activator activity; GO:0005096 GTPase activator activity; ",{"$nulls":3},"IPR011989; IPR016024; ","Armadillo-like helical; Armadillo-type fold; \r"]
["P52565","Rho GDP-dissociation inhibitor 1 OS=Homo sapiens OX=9606 GN=ARHGDIA","ARHGDIA",23.207,87.383,33.3,8,20,8,0.968,0.991,0.988,0.996,1.017,0.994,1.02,0.124,"cytoplasm\r","GO:0044700 single organism signaling; GO:0051093 negative regulation of developmental process; GO:0045666 positive regulation of neuron differentiation; GO:0010941 regulation of cell death; GO:0007166 cell surface receptor signaling pathway; GO:0023051 regulation of signaling; GO:0051129 negative regulation of cellular component organization; GO:0048869 cellular developmental process; GO:0051241 negative regulation of multicellular organismal process; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0051130 positive regulation of cellular component organization; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0051240 positive regulation of multicellular organismal process; GO:0044093 positive regulation of molecular function; GO:0051493 regulation of cytoskeleton organization; GO:0050771 negative regulation of axonogenesis; GO:0045596 negative regulation of cell differentiation; GO:0010720 positive regulation of cell development; GO:0051056 regulation of small GTPase mediated signal transduction; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0048699 generation of neurons; GO:0031346 positive regulation of cell projection organization; GO:0044763 single-organism cellular process; GO:0051962 positive regulation of nervous system development; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0050768 negative regulation of neurogenesis; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:0045664 regulation of neuron differentiation; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0045665 negative regulation of neuron differentiation; GO:0043087 regulation of GTPase activity; GO:0065009 regulation of molecular function; GO:0010721 negative regulation of cell development; GO:0051094 positive regulation of developmental process; GO:0048856 anatomical structure development; GO:0060548 negative regulation of cell death; GO:0010975 regulation of neuron projection development; GO:2000026 regulation of multicellular organismal development; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0007162 negative regulation of cell adhesion; GO:0043069 negative regulation of programmed cell death; GO:0032956 regulation of actin cytoskeleton organization; GO:0043067 regulation of programmed cell death; GO:0010770 positive regulation of cell morphogenesis involved in differentiation; GO:0046578 regulation of Ras protein signal transduction; GO:0031344 regulation of cell projection organization; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:0045597 positive regulation of cell differentiation; GO:0030154 cell differentiation; GO:0051961 negative regulation of nervous system development; GO:0051345 positive regulation of hydrolase activity; GO:0043066 negative regulation of apoptotic process; GO:0050772 positive regulation of axonogenesis; GO:2000249 regulation of actin cytoskeleton reorganization; GO:0031345 negative regulation of cell projection organization; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0010771 negative regulation of cell morphogenesis involved in differentiation; GO:1902531 regulation of intracellular signal transduction; GO:0043547 positive regulation of GTPase activity; GO:0048731 system development; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0033043 regulation of organelle organization; GO:0010977 negative regulation of neuron projection development; GO:0032970 regulation of actin filament-based process; GO:0048518 positive regulation of biological process; GO:0030155 regulation of cell adhesion; GO:0050770 regulation of axonogenesis; GO:0043085 positive regulation of catalytic activity; GO:0010976 positive regulation of neuron projection development; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0006928 movement of cell or subcellular component; GO:0050769 positive regulation of neurogenesis; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:0051128 regulation of cellular component organization; GO:0035023 regulation of Rho protein signal transduction; GO:0022604 regulation of cell morphogenesis; GO:0050793 regulation of developmental process; GO:0071526 semaphorin-plexin signaling pathway; GO:0042981 regulation of apoptotic process; GO:0050767 regulation of neurogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005094 Rho GDP-dissociation inhibitor activity; GO:0030234 enzyme regulator activity; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0005092 GDP-dissociation inhibitor activity; GO:0005488 binding; GO:0030695 GTPase regulator activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0008047 enzyme activator activity; GO:0005096 GTPase activator activity; ","K12462","ARHGDI; Rho GDP-dissociation inhibitor","hsa04722 Neurotrophin signaling pathway - Homo sapiens (human); hsa04962 Vasopressin-regulated water reabsorption - Homo sapiens (human); ","IPR014756; IPR024792; ","Immunoglobulin E-set; Rho GDP-dissociation inhibitor domain; \r"]
["P52566","Rho GDP-dissociation inhibitor 2 OS=Homo sapiens OX=9606 GN=ARHGDIB","ARHGDIB",22.988,101.32,46.3,7,26,7,0.967,0.944,0.952,1.036,1.074,1.044,1.102,0.00176,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0051093 negative regulation of developmental process; GO:0007162 negative regulation of cell adhesion; GO:0032956 regulation of actin cytoskeleton organization; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0051241 negative regulation of multicellular organismal process; GO:0046578 regulation of Ras protein signal transduction; GO:1901164 negative regulation of trophoblast cell migration; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:1901163 regulation of trophoblast cell migration; GO:0040013 negative regulation of locomotion; GO:0010646 regulation of cell communication; GO:0051345 positive regulation of hydrolase activity; GO:0032879 regulation of localization; GO:2000145 regulation of cell motility; GO:2000249 regulation of actin cytoskeleton reorganization; GO:0044093 positive regulation of molecular function; GO:0051775 response to redox state; GO:0007275 multicellular organism development; GO:0051493 regulation of cytoskeleton organization; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:0051056 regulation of small GTPase mediated signal transduction; GO:0032502 developmental process; GO:1902531 regulation of intracellular signal transduction; GO:0043547 positive regulation of GTPase activity; GO:0051270 regulation of cellular component movement; GO:0043900 regulation of multi-organism process; GO:0044763 single-organism cellular process; GO:0033043 regulation of organelle organization; GO:0032970 regulation of actin filament-based process; GO:0030334 regulation of cell migration; GO:2000146 negative regulation of cell motility; GO:0032501 multicellular organismal process; GO:0030155 regulation of cell adhesion; GO:0043085 positive regulation of catalytic activity; GO:0043901 negative regulation of multi-organism process; GO:2000241 regulation of reproductive process; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:0030336 negative regulation of cell migration; GO:0044767 single-organism developmental process; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:2000242 negative regulation of reproductive process; GO:0006928 movement of cell or subcellular component; GO:0043087 regulation of GTPase activity; GO:0065009 regulation of molecular function; GO:0051128 regulation of cellular component organization; GO:0040012 regulation of locomotion; GO:0035023 regulation of Rho protein signal transduction; GO:0048856 anatomical structure development; GO:0050793 regulation of developmental process; GO:0071461 cellular response to redox state; GO:0051271 negative regulation of cellular component movement; GO:2000026 regulation of multicellular organismal development; GO:0065007 biological regulation; ","GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0031267 small GTPase binding; GO:0017048 Rho GTPase binding; GO:0048365 Rac GTPase binding; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0005092 GDP-dissociation inhibitor activity; GO:0030695 GTPase regulator activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0017111 nucleoside-triphosphatase activity; GO:0098772 molecular function regulator; GO:0005094 Rho GDP-dissociation inhibitor activity; GO:0016462 pyrophosphatase activity; GO:0030234 enzyme regulator activity; GO:0003824 catalytic activity; GO:0017016 Ras GTPase binding; GO:0005488 binding; GO:0003924 GTPase activity; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0051020 GTPase binding; GO:0008047 enzyme activator activity; GO:0019899 enzyme binding; GO:0005096 GTPase activator activity; ","K12462","ARHGDI; Rho GDP-dissociation inhibitor","hsa04722 Neurotrophin signaling pathway - Homo sapiens (human); hsa04962 Vasopressin-regulated water reabsorption - Homo sapiens (human); ","IPR014756; IPR024792; ","Immunoglobulin E-set; Rho GDP-dissociation inhibitor domain; \r"]
["P52630","Signal transducer and activator of transcription 2 OS=Homo sapiens OX=9606 GN=STAT2","STAT2",97.915,30.384,6.5,4,5,4,0.776,0.946,0.779,1.216,1.148,1.134,1.399,0.00788,"cytoplasm\r","GO:0044700 single organism signaling; GO:0007166 cell surface receptor signaling pathway; GO:0097659 nucleic acid-templated transcription; GO:0023051 regulation of signaling; GO:0098542 defense response to other organism; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0031347 regulation of defense response; GO:0010821 regulation of mitochondrion organization; GO:0044237 cellular metabolic process; GO:0071345 cellular response to cytokine stimulus; GO:0009607 response to biotic stimulus; GO:0009605 response to external stimulus; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0045088 regulation of innate immune response; GO:0043170 macromolecule metabolic process; GO:0090140 regulation of mitochondrial fission; GO:0044419 interspecies interaction between organisms; GO:0070887 cellular response to chemical stimulus; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0051174 regulation of phosphorus metabolic process; GO:0097696 STAT cascade; GO:0031326 regulation of cellular biosynthetic process; GO:0034097 response to cytokine; GO:0080090 regulation of primary metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0034340 response to type I interferon; GO:0032774 RNA biosynthetic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0031323 regulation of cellular metabolic process; GO:0023052 signaling; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0032268 regulation of cellular protein metabolic process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0051607 defense response to virus; GO:0006351 transcription, DNA-templated; GO:0060759 regulation of response to cytokine stimulus; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0002682 regulation of immune system process; GO:0060338 regulation of type I interferon-mediated signaling pathway; GO:0019220 regulation of phosphate metabolic process; GO:0006952 defense response; GO:1901362 organic cyclic compound biosynthetic process; GO:0009615 response to virus; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0060337 type I interferon signaling pathway; GO:0007259 JAK-STAT cascade; GO:0006725 cellular aromatic compound metabolic process; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031399 regulation of protein modification process; GO:0001959 regulation of cytokine-mediated signaling pathway; GO:0080134 regulation of response to stress; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0045087 innate immune response; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0016032 viral process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0071357 cellular response to type I interferon; GO:0009059 macromolecule biosynthetic process; GO:0009966 regulation of signal transduction; GO:0019221 cytokine-mediated signaling pathway; GO:0009987 cellular process; GO:0006355 regulation of transcription, DNA-templated; GO:0006950 response to stress; GO:0035556 intracellular signal transduction; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0001932 regulation of protein phosphorylation; GO:0033043 regulation of organelle organization; GO:0006807 nitrogen compound metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0002376 immune system process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0051246 regulation of protein metabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0010467 gene expression; GO:0051128 regulation of cellular component organization; GO:0006955 immune response; GO:0050793 regulation of developmental process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0071944 cell periphery; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0044422 organelle part; GO:0005886 plasma membrane; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003677 DNA binding; GO:0042802 identical protein binding; GO:0005488 binding; GO:0001071 nucleic acid binding transcription factor activity; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0004871 signal transducer activity; GO:0003700 transcription factor activity, sequence-specific DNA binding; ","K11221","STAT2; signal transducer and activator of transcription 2","hsa04380 Osteoclast differentiation - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa04625 C-type lectin receptor signaling pathway - Homo sapiens (human); hsa05168 Herpes simplex infection - Homo sapiens (human); hsa05160 Hepatitis C - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa04217 Necroptosis - Homo sapiens (human); hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human); hsa05167 Kaposi's sarcoma-associated herpesvirus infection - Homo sapiens (human); hsa05162 Measles - Homo sapiens (human); hsa05161 Hepatitis B - Homo sapiens (human); hsa04062 Chemokine signaling pathway - Homo sapiens (human); hsa05164 Influenza A - Homo sapiens (human); hsa04630 Jak-STAT signaling pathway - Homo sapiens (human); ","IPR022756; IPR013801; IPR008967; IPR011992; IPR013800; IPR000980; IPR012345; IPR013799; IPR015988; ","\"Signal transducer and activation of transcription 2, C-terminal; STAT transcription factor, DNA-binding; p53-like transcription factor, DNA-binding; EF-hand domain pair; STAT transcription factor, all-alpha domain; SH2 domain; STAT transcription factor, DNA-binding, subdomain; STAT transcription factor, protein interaction; STAT transcription factor, coiled coil; \"\r"]
["P52789","Hexokinase-2 OS=Homo sapiens OX=9606 GN=HK2","HK2",102.38,4.5245,5.8,5,5,3,0.882,0.944,0.965,1.086,0.982,1.14,1.149,0.0555,"cytoplasm\r","GO:0009116 nucleoside metabolic process; GO:0065008 regulation of biological quality; GO:0048732 gland development; GO:0006165 nucleoside diphosphate phosphorylation; GO:0019362 pyridine nucleotide metabolic process; GO:0006096 glycolytic process; GO:0042593 glucose homeostasis; GO:0009185 ribonucleoside diphosphate metabolic process; GO:0010821 regulation of mitochondrion organization; GO:0044237 cellular metabolic process; GO:0006006 glucose metabolic process; GO:0072595 maintenance of protein localization in organelle; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0044262 cellular carbohydrate metabolic process; GO:0032879 regulation of localization; GO:0001678 cellular glucose homeostasis; GO:0015758 glucose transport; GO:0032787 monocarboxylic acid metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0090559 regulation of membrane permeability; GO:0033365 protein localization to organelle; GO:0051651 maintenance of location in cell; GO:0008104 protein localization; GO:0046324 regulation of glucose import; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0051220 cytoplasmic sequestering of protein; GO:0051716 cellular response to stimulus; GO:0009179 purine ribonucleoside diphosphate metabolic process; GO:0032507 maintenance of protein location in cell; GO:1903599 positive regulation of mitophagy; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0061620 glycolytic process through glucose-6-phosphate; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:1904923 regulation of mitophagy in response to mitochondrial depolarization; GO:0006732 coenzyme metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0005975 carbohydrate metabolic process; GO:0032501 multicellular organismal process; GO:0010506 regulation of autophagy; GO:0061718 glucose catabolic process to pyruvate; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0048513 animal organ development; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0008645 hexose transport; GO:0010508 positive regulation of autophagy; GO:0019674 NAD metabolic process; GO:0044710 single-organism metabolic process; GO:0009126 purine nucleoside monophosphate metabolic process; GO:0072655 establishment of protein localization to mitochondrion; GO:0043436 oxoacid metabolic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0033554 cellular response to stress; GO:0016310 phosphorylation; GO:0007006 mitochondrial membrane organization; GO:0015749 monosaccharide transport; GO:0046496 nicotinamide nucleotide metabolic process; GO:0009259 ribonucleotide metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0006735 NADH regeneration; GO:0030879 mammary gland development; GO:0051156 glucose 6-phosphate metabolic process; GO:0046483 heterocycle metabolic process; GO:1902578 single-organism localization; GO:0006139 nucleobase-containing compound metabolic process; GO:0009896 positive regulation of catabolic process; GO:0046835 carbohydrate phosphorylation; GO:0033500 carbohydrate homeostasis; GO:1901135 carbohydrate derivative metabolic process; GO:0007275 multicellular organism development; GO:2000378 negative regulation of reactive oxygen species metabolic process; GO:0034613 cellular protein localization; GO:0009119 ribonucleoside metabolic process; GO:0048878 chemical homeostasis; GO:0006950 response to stress; GO:0048731 system development; GO:0071702 organic substance transport; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0006163 purine nucleotide metabolic process; GO:0045184 establishment of protein localization; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0031325 positive regulation of cellular metabolic process; GO:0019637 organophosphate metabolic process; GO:0012501 programmed cell death; GO:0019320 hexose catabolic process; GO:0051179 localization; GO:0019318 hexose metabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0006757 ATP generation from ADP; GO:0046365 monosaccharide catabolic process; GO:0042278 purine nucleoside metabolic process; GO:0072594 establishment of protein localization to organelle; GO:0046031 ADP metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0006839 mitochondrial transport; GO:0009117 nucleotide metabolic process; GO:0031331 positive regulation of cellular catabolic process; GO:0044699 single-organism process; GO:0046939 nucleotide phosphorylation; GO:0009135 purine nucleoside diphosphate metabolic process; GO:0072524 pyridine-containing compound metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0061615 glycolytic process through fructose-6-phosphate; GO:0051234 establishment of localization; GO:0002931 response to ischemia; GO:0051130 positive regulation of cellular component organization; GO:0009893 positive regulation of metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0006915 apoptotic process; GO:0007005 mitochondrion organization; GO:0010827 regulation of glucose transport; GO:0033036 macromolecule localization; GO:0007595 lactation; GO:0032502 developmental process; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0055114 oxidation-reduction process; GO:0019725 cellular homeostasis; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0051186 cofactor metabolic process; GO:0016052 carbohydrate catabolic process; GO:1902589 single-organism organelle organization; GO:0044723 single-organism carbohydrate metabolic process; GO:0050789 regulation of biological process; GO:0010638 positive regulation of organelle organization; GO:0019222 regulation of metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:2000377 regulation of reactive oxygen species metabolic process; GO:0016043 cellular component organization; GO:0072656 maintenance of protein location in mitochondrion; GO:0006725 cellular aromatic compound metabolic process; GO:0006734 NADH metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0055082 cellular chemical homeostasis; GO:0071704 organic substance metabolic process; GO:0061621 canonical glycolysis; GO:0042592 homeostatic process; GO:0006090 pyruvate metabolic process; GO:0046902 regulation of mitochondrial membrane permeability; GO:1904925 positive regulation of mitophagy in response to mitochondrial depolarization; GO:0005996 monosaccharide metabolic process; GO:0008643 carbohydrate transport; GO:0034641 cellular nitrogen compound metabolic process; GO:0051235 maintenance of location; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0009987 cellular process; GO:0098780 response to mitochondrial depolarisation; GO:0009132 nucleoside diphosphate metabolic process; GO:0046034 ATP metabolic process; GO:0007589 body fluid secretion; GO:0035795 negative regulation of mitochondrial membrane permeability; GO:0050878 regulation of body fluid levels; GO:0044724 single-organism carbohydrate catabolic process; GO:0008637 apoptotic mitochondrial changes; GO:0045185 maintenance of protein location; GO:0051049 regulation of transport; GO:0044712 single-organism catabolic process; GO:0044802 single-organism membrane organization; GO:0006807 nitrogen compound metabolic process; GO:0033043 regulation of organelle organization; GO:0044282 small molecule catabolic process; GO:0070585 protein localization to mitochondrion; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0010822 positive regulation of mitochondrion organization; GO:0046128 purine ribonucleoside metabolic process; GO:0070727 cellular macromolecule localization; GO:0006007 glucose catabolic process; GO:0008219 cell death; GO:1903146 regulation of mitophagy; GO:1905709 negative regulation of membrane permeability; GO:0044767 single-organism developmental process; GO:0019752 carboxylic acid metabolic process; GO:0051128 regulation of cellular component organization; GO:0009150 purine ribonucleotide metabolic process; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0019867 outer membrane; GO:0044429 mitochondrial part; GO:0098588 bounding membrane of organelle; GO:0031090 organelle membrane; GO:0005741 mitochondrial outer membrane; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005740 mitochondrial envelope; GO:0005622 intracellular; GO:0044464 cell part; GO:0031975 envelope; GO:0098805 whole membrane; GO:0031968 organelle outer membrane; GO:0043227 membrane-bounded organelle; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0005515 protein binding; GO:0048029 monosaccharide binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016301 kinase activity; GO:0008865 fructokinase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0004340 glucokinase activity; GO:0016740 transferase activity; GO:0004396 hexokinase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0019158 mannokinase activity; GO:0005536 glucose binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0032549 ribonucleoside binding; GO:0019200 carbohydrate kinase activity; GO:0097367 carbohydrate derivative binding; GO:0030246 carbohydrate binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0036094 small molecule binding; ","K00844","HK; hexokinase [EC:2.7.1.1]","hsa00051 Fructose and mannose metabolism - Homo sapiens (human); hsa04066 HIF-1 signaling pathway - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa04973 Carbohydrate digestion and absorption - Homo sapiens (human); hsa00500 Starch and sucrose metabolism - Homo sapiens (human); hsa04910 Insulin signaling pathway - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); hsa05230 Central carbon metabolism in cancer - Homo sapiens (human); hsa00524 Neomycin, kanamycin and gentamicin biosynthesis - Homo sapiens (human); hsa04930 Type II diabetes mellitus - Homo sapiens (human); hsa00052 Galactose metabolism - Homo sapiens (human); hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human); hsa00520 Amino sugar and nucleotide sugar metabolism - Homo sapiens (human); ","IPR022672; IPR022673; ","\"Hexokinase, N-terminal; Hexokinase, C-terminal; \"\r"]
["P52888","Thimet oligopeptidase OS=Homo sapiens OX=9606 GN=THOP1","THOP1",78.839,42.611,12.6,7,7,7,0.954,0.981,0.963,1.061,1.069,0.978,1.072,0.0798,"cytoplasm\r","GO:0008152 metabolic process; GO:0006518 peptide metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0006508 proteolysis; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0043603 cellular amide metabolic process; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0009987 cellular process; GO:0071704 organic substance metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031974 membrane-enclosed lumen; GO:0031970 organelle envelope lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0005758 mitochondrial intermembrane space; GO:0031975 envelope; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; ","GO:0004175 endopeptidase activity; GO:0004222 metalloendopeptidase activity; GO:0008233 peptidase activity; GO:0042277 peptide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0008237 metallopeptidase activity; GO:0033218 amide binding; ","K01392","THOP1; thimet oligopeptidase [EC:3.4.24.15]","hsa04614 Renin-angiotensin system - Homo sapiens (human); hsa05143 African trypanosomiasis - Homo sapiens (human); ","IPR024077; IPR001567; IPR024080; IPR024079; ","\"Neurolysin/Thimet oligopeptidase, domain 2; Peptidase M3A/M3B catalytic domain; Neurolysin/Thimet oligopeptidase, N-terminal; Metallopeptidase, catalytic domain; \"\r"]
["P52907","F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1","CAPZA1",32.922,165.78,44.4,9,19,8,0.959,1.018,0.974,1.044,1.044,1.027,1.056,0.0438,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0050794 regulation of cellular process; GO:0030833 regulation of actin filament polymerization; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0030835 negative regulation of actin filament depolymerization; GO:0032956 regulation of actin cytoskeleton organization; GO:0051129 negative regulation of cellular component organization; GO:0044699 single-organism process; GO:0044087 regulation of cellular component biogenesis; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0030832 regulation of actin filament length; GO:0050896 response to stimulus; GO:0045087 innate immune response; GO:0007599 hemostasis; GO:1901880 negative regulation of protein depolymerization; GO:0009611 response to wounding; GO:0051693 actin filament capping; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0032535 regulation of cellular component size; GO:0032271 regulation of protein polymerization; GO:0051493 regulation of cytoskeleton organization; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0031333 negative regulation of protein complex assembly; GO:0071822 protein complex subunit organization; GO:0050878 regulation of body fluid levels; GO:0006950 response to stress; GO:0051494 negative regulation of cytoskeleton organization; GO:1901879 regulation of protein depolymerization; GO:0044763 single-organism cellular process; GO:0033043 regulation of organelle organization; GO:0032970 regulation of actin filament-based process; GO:0002376 immune system process; GO:0032501 multicellular organismal process; GO:0043933 macromolecular complex subunit organization; GO:0010639 negative regulation of organelle organization; GO:0008064 regulation of actin polymerization or depolymerization; GO:0050789 regulation of biological process; GO:0043254 regulation of protein complex assembly; GO:0051016 barbed-end actin filament capping; GO:0042060 wound healing; GO:0043242 negative regulation of protein complex disassembly; GO:1902904 negative regulation of supramolecular fiber organization; GO:0006928 movement of cell or subcellular component; GO:0090066 regulation of anatomical structure size; GO:0030837 negative regulation of actin filament polymerization; GO:0043244 regulation of protein complex disassembly; GO:0030834 regulation of actin filament depolymerization; GO:0051128 regulation of cellular component organization; GO:0006952 defense response; GO:0050817 coagulation; GO:0070271 protein complex biogenesis; GO:0032272 negative regulation of protein polymerization; GO:0006955 immune response; GO:1902903 regulation of supramolecular fiber organization; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0071203 WASH complex; GO:0031982 vesicle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0008290 F-actin capping protein complex; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0015629 actin cytoskeleton; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005856 cytoskeleton; GO:0043226 organelle; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0003779 actin binding; GO:0050839 cell adhesion molecule binding; GO:0005515 protein binding; GO:0008092 cytoskeletal protein binding; GO:0005488 binding; GO:0045296 cadherin binding; ","K10364","CAPZA; capping protein (actin filament) muscle Z-line, alpha","hsa04144 Endocytosis - Homo sapiens (human); "]
["P53004","Biliverdin reductase A OS=Homo sapiens OX=9606 GN=BLVRA","BLVRA",33.428,31.894,28,9,11,9,1.028,0.976,1.005,0.983,1.03,0.965,0.99,0.691,"cytoplasm\r","GO:0006725 cellular aromatic compound metabolic process; GO:0042167 heme catabolic process; GO:0044699 single-organism process; GO:0042168 heme metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0008152 metabolic process; GO:0006778 porphyrin-containing compound metabolic process; GO:0051187 cofactor catabolic process; GO:0046483 heterocycle metabolic process; GO:0033015 tetrapyrrole catabolic process; GO:0044248 cellular catabolic process; GO:1901361 organic cyclic compound catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009987 cellular process; GO:0042440 pigment metabolic process; GO:0055114 oxidation-reduction process; GO:0044712 single-organism catabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0051186 cofactor metabolic process; GO:0019439 aromatic compound catabolic process; GO:1901575 organic substance catabolic process; GO:1901565 organonitrogen compound catabolic process; GO:0046149 pigment catabolic process; GO:0006787 porphyrin-containing compound catabolic process; GO:0044710 single-organism metabolic process; GO:0033013 tetrapyrrole metabolic process; GO:0009056 catabolic process; GO:0046700 heterocycle catabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors; GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0008270 zinc ion binding; GO:0004074 biliverdin reductase activity; GO:0016491 oxidoreductase activity; ","K00214","BLVRA; biliverdin reductase [EC:1.3.1.24]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00860 Porphyrin and chlorophyll metabolism - Homo sapiens (human); ","IPR000683; IPR016040; IPR015249; ","\"Oxidoreductase, N-terminal; NAD(P)-binding domain; Biliverdin reductase, catalytic; \"\r"]
["P53367","Arfaptin-1 OS=Homo sapiens OX=9606 GN=ARFIP1","ARFIP1",41.738,35.522,25.5,8,12,8,0.971,1.004,0.979,1.014,0.988,0.999,1.016,0.276,"cytoplasm\r","GO:0030833 regulation of actin filament polymerization; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0065008 regulation of biological quality; GO:0032956 regulation of actin cytoskeleton organization; GO:0051046 regulation of secretion; GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation; GO:0044699 single-organism process; GO:0044087 regulation of cellular component biogenesis; GO:0030832 regulation of actin filament length; GO:0070201 regulation of establishment of protein localization; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0051649 establishment of localization in cell; GO:0032879 regulation of localization; GO:0032535 regulation of cellular component size; GO:0006886 intracellular protein transport; GO:0032271 regulation of protein polymerization; GO:0032880 regulation of protein localization; GO:0051493 regulation of cytoskeleton organization; GO:0050708 regulation of protein secretion; GO:0034613 cellular protein localization; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0009987 cellular process; GO:0051125 regulation of actin nucleation; GO:0051049 regulation of transport; GO:0044763 single-organism cellular process; GO:0033043 regulation of organelle organization; GO:0071702 organic substance transport; GO:0032970 regulation of actin filament-based process; GO:1903530 regulation of secretion by cell; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:0008064 regulation of actin polymerization or depolymerization; GO:0070727 cellular macromolecule localization; GO:0043254 regulation of protein complex assembly; GO:0050789 regulation of biological process; GO:0090066 regulation of anatomical structure size; GO:0051223 regulation of protein transport; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; GO:1902903 regulation of supramolecular fiber organization; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0098588 bounding membrane of organelle; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0032588 trans-Golgi network membrane; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0098791 Golgi subcompartment; GO:0005802 trans-Golgi network; GO:0044431 Golgi apparatus part; GO:0005794 Golgi apparatus; GO:0043227 membrane-bounded organelle; GO:0031984 organelle subcompartment; GO:0044444 cytoplasmic part; ","GO:1901981 phosphatidylinositol phosphate binding; GO:0050839 cell adhesion molecule binding; GO:0005488 binding; GO:0005543 phospholipid binding; GO:0035091 phosphatidylinositol binding; GO:0043167 ion binding; GO:0045296 cadherin binding; GO:0008289 lipid binding; GO:0043168 anion binding; GO:0005515 protein binding; GO:0019904 protein domain specific binding; GO:0070273 phosphatidylinositol-4-phosphate binding; ","K20314",null,null,"IPR010504; IPR027267; ","Arfaptin homology (AH) domain; Arfaptin homology (AH) domain/BAR domain; \r"]
["P53396","ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY","ACLY",120.84,164.61,24.3,24,40,24,1.131,1.14,1.135,0.869,0.889,0.869,0.771,2.58e-06,"cytoplasm\r","GO:0051188 cofactor biosynthetic process; GO:0045321 leukocyte activation; GO:0016053 organic acid biosynthetic process; GO:0006066 alcohol metabolic process; GO:0035337 fatty-acyl-CoA metabolic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0035384 thioester biosynthetic process; GO:0044272 sulfur compound biosynthetic process; GO:0008610 lipid biosynthetic process; GO:0051234 establishment of localization; GO:0006085 acetyl-CoA biosynthetic process; GO:0008152 metabolic process; GO:0009893 positive regulation of metabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0009108 coenzyme biosynthetic process; GO:0006629 lipid metabolic process; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0006790 sulfur compound metabolic process; GO:0072350 tricarboxylic acid metabolic process; GO:0002443 leukocyte mediated immunity; GO:0071616 acyl-CoA biosynthetic process; GO:0044281 small molecule metabolic process; GO:0002446 neutrophil mediated immunity; GO:0008202 steroid metabolic process; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0006107 oxaloacetate metabolic process; GO:1901617 organic hydroxy compound biosynthetic process; GO:0006732 coenzyme metabolic process; GO:0035336 long-chain fatty-acyl-CoA metabolic process; GO:0006084 acetyl-CoA metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0006633 fatty acid biosynthetic process; GO:0035338 long-chain fatty-acyl-CoA biosynthetic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0051186 cofactor metabolic process; GO:0006101 citrate metabolic process; GO:0006810 transport; GO:0046394 carboxylic acid biosynthetic process; GO:0050789 regulation of biological process; GO:0032940 secretion by cell; GO:0044710 single-organism metabolic process; GO:0019222 regulation of metabolic process; GO:0043299 leukocyte degranulation; GO:0006082 organic acid metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0043436 oxoacid metabolic process; GO:0050794 regulation of cellular process; GO:0043648 dicarboxylic acid metabolic process; GO:0002283 neutrophil activation involved in immune response; GO:0046949 fatty-acyl-CoA biosynthetic process; GO:1901615 organic hydroxy compound metabolic process; GO:1902652 secondary alcohol metabolic process; GO:0002252 immune effector process; GO:1902653 secondary alcohol biosynthetic process; GO:0050896 response to stimulus; GO:0016125 sterol metabolic process; GO:0071704 organic substance metabolic process; GO:0016126 sterol biosynthetic process; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0006695 cholesterol biosynthetic process; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0008203 cholesterol metabolic process; GO:0044711 single-organism biosynthetic process; GO:0016192 vesicle-mediated transport; GO:0035383 thioester metabolic process; GO:0046165 alcohol biosynthetic process; GO:0002376 immune system process; GO:0006631 fatty acid metabolic process; GO:0043312 neutrophil degranulation; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0002263 cell activation involved in immune response; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0006637 acyl-CoA metabolic process; GO:0006694 steroid biosynthetic process; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0006793 phosphorus metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0044283 small molecule biosynthetic process; GO:0019752 carboxylic acid metabolic process; GO:0001775 cell activation; GO:0006955 immune response; GO:0051179 localization; GO:0072330 monocarboxylic acid biosynthetic process; GO:0065007 biological regulation; GO:0006887 exocytosis; ","GO:0034774 secretory granule lumen; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0009346 citrate lyase complex; GO:0042582 azurophil granule; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0048037 cofactor binding; GO:0003878 ATP citrate synthase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0016746 transferase activity, transferring acyl groups; GO:0097367 carbohydrate derivative binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K01648","ACLY; ATP citrate (pro-S)-lyase [EC:2.3.3.8]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00020 Citrate cycle (TCA cycle) - Homo sapiens (human); ","IPR016142; IPR032263; IPR005811; IPR013816; IPR016040; IPR003781; IPR016143; IPR016102; ","\"Citrate synthase-like, large alpha subdomain; ATP-citrate synthase, citrate-binding domain; ATP-citrate lyase/succinyl-CoA ligase; ATP-grasp fold, subdomain 2; NAD(P)-binding domain; CoA-binding; Citrate synthase-like, small alpha subdomain; Succinyl-CoA synthetase-like; \"\r"]
["P53602","Diphosphomevalonate decarboxylase OS=Homo sapiens OX=9606 GN=MVD","MVD",43.404,34.806,22.5,8,11,8,1.046,1.091,1.097,0.91,0.898,0.905,0.839,0.000345,"nucleus\r","GO:0050794 regulation of cellular process; GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway; GO:0042127 regulation of cell proliferation; GO:1901615 organic hydroxy compound metabolic process; GO:1902652 secondary alcohol metabolic process; GO:0006066 alcohol metabolic process; GO:1902653 secondary alcohol biosynthetic process; GO:0008654 phospholipid biosynthetic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044255 cellular lipid metabolic process; GO:0006489 dolichyl diphosphate biosynthetic process; GO:0016125 sterol metabolic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0008610 lipid biosynthetic process; GO:0071704 organic substance metabolic process; GO:0008299 isoprenoid biosynthetic process; GO:0016126 sterol biosynthetic process; GO:0008152 metabolic process; GO:0046465 dolichyl diphosphate metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0006695 cholesterol biosynthetic process; GO:0046490 isopentenyl diphosphate metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0009987 cellular process; GO:0006629 lipid metabolic process; GO:0006790 sulfur compound metabolic process; GO:0006720 isoprenoid metabolic process; GO:0008203 cholesterol metabolic process; GO:0044711 single-organism biosynthetic process; GO:0006488 dolichol-linked oligosaccharide biosynthetic process; GO:0044281 small molecule metabolic process; GO:0008202 steroid metabolic process; GO:0035383 thioester metabolic process; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0046165 alcohol biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:1901617 organic hydroxy compound biosynthetic process; GO:0006732 coenzyme metabolic process; GO:0006084 acetyl-CoA metabolic process; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:1901576 organic substance biosynthetic process; GO:0006637 acyl-CoA metabolic process; GO:0044249 cellular biosynthetic process; GO:0051186 cofactor metabolic process; GO:0006694 steroid biosynthetic process; GO:0006490 oligosaccharide-lipid intermediate biosynthetic process; GO:0090407 organophosphate biosynthetic process; GO:0050789 regulation of biological process; GO:0009240 isopentenyl diphosphate biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0044283 small molecule biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0006644 phospholipid metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0008284 positive regulation of cell proliferation; GO:0065007 biological regulation; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:0030544 Hsp70 protein binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0016830 carbon-carbon lyase activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0016831 carboxy-lyase activity; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0031072 heat shock protein binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0016829 lyase activity; GO:0000166 nucleotide binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0042803 protein homodimerization activity; GO:0004163 diphosphomevalonate decarboxylase activity; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; ","K01597","MVD; diphosphomevalonate decarboxylase [EC:4.1.1.33]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00900 Terpenoid backbone biosynthesis - Homo sapiens (human); ","IPR020568; IPR006204; IPR014721; IPR013750; ","\"Ribosomal protein S5 domain 2-type fold; GHMP kinase N-terminal domain; Ribosomal protein S5 domain 2-type fold, subgroup; GHMP kinase, C-terminal domain; \"\r"]
["P53621","Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA","COPA",138.34,139.58,25.6,25,43,25,0.998,0.998,0.975,1.002,1.027,1.018,1.026,0.0757,"cytoplasm\r","GO:0044707 single-multicellular organism process; GO:0046907 intracellular transport; GO:0065008 regulation of biological quality; GO:0007586 digestion; GO:0044699 single-organism process; GO:0048193 Golgi vesicle transport; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0051649 establishment of localization in cell; GO:1902578 single-organism localization; GO:0006886 intracellular protein transport; GO:0032941 secretion by tissue; GO:0030157 pancreatic juice secretion; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0034613 cellular protein localization; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0007589 body fluid secretion; GO:0003008 system process; GO:0050878 regulation of body fluid levels; GO:0006891 intra-Golgi vesicle-mediated transport; GO:0016192 vesicle-mediated transport; GO:0071702 organic substance transport; GO:0032501 multicellular organismal process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:0070727 cellular macromolecule localization; GO:0006890 retrograde vesicle-mediated transport, Golgi to ER; GO:0022600 digestive system process; GO:0051179 localization; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0098796 membrane protein complex; GO:0030137 COPI-coated vesicle; GO:0030660 Golgi-associated vesicle membrane; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0030120 vesicle coat; GO:0030663 COPI-coated vesicle membrane; GO:0005623 cell; GO:0030662 coated vesicle membrane; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0030126 COPI vesicle coat; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0048475 coated membrane; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0005829 cytosol; GO:0005798 Golgi-associated vesicle; GO:0005576 extracellular region; GO:0030135 coated vesicle; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044432 endoplasmic reticulum part; GO:0030117 membrane coat; GO:0030133 transport vesicle; GO:0043234 protein complex; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005198 structural molecule activity; GO:0005102 receptor binding; GO:0005488 binding; GO:0005179 hormone activity; ","K05236",null,null,"IPR006692; IPR017986; IPR011048; IPR015943; IPR024977; IPR010714; ","\"Coatomer, WD associated region; WD40-repeat-containing domain; Cytochrome cd1-nitrite reductase-like, haem d1 domain; WD40/YVTN repeat-like-containing domain; Anaphase-promoting complex subunit 4, WD40 domain; Coatomer, alpha subunit, C-terminal; \"\r"]
["P53634","Dipeptidyl peptidase 1 OS=Homo sapiens OX=9606 GN=CTSC","CTSC",51.853,17.512,10.8,4,5,4,0.909,1.086,1.003,0.978,0.967,1.064,1.004,0.932,"plasma membrane\r","GO:0044085 cellular component biogenesis; GO:0010941 regulation of cell death; GO:0032270 positive regulation of cellular protein metabolic process; GO:0045321 leukocyte activation; GO:0048208 COPII vesicle coating; GO:0044237 cellular metabolic process; GO:1903364 positive regulation of cellular protein catabolic process; GO:0008152 metabolic process; GO:0065003 macromolecular complex assembly; GO:0048199 vesicle targeting, to, from or within Golgi; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0001906 cell killing; GO:1903362 regulation of cellular protein catabolic process; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0002443 leukocyte mediated immunity; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0002456 T cell mediated immunity; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0031323 regulation of cellular metabolic process; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0001909 leukocyte mediated cytotoxicity; GO:0030163 protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0043068 positive regulation of programmed cell death; GO:0050794 regulation of cellular process; GO:0051640 organelle localization; GO:0046907 intracellular transport; GO:0002283 neutrophil activation involved in immune response; GO:0043067 regulation of programmed cell death; GO:0044267 cellular protein metabolic process; GO:0001913 T cell mediated cytotoxicity; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0009896 positive regulation of catabolic process; GO:0044248 cellular catabolic process; GO:0042176 regulation of protein catabolic process; GO:0002449 lymphocyte mediated immunity; GO:0009966 regulation of signal transduction; GO:0006461 protein complex assembly; GO:0090114 COPII-coated vesicle budding; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0030162 regulation of proteolysis; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0051656 establishment of organelle localization; GO:0002263 cell activation involved in immune response; GO:0045055 regulated exocytosis; GO:0051247 positive regulation of protein metabolic process; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0061024 membrane organization; GO:0006900 membrane budding; GO:0001775 cell activation; GO:0012501 programmed cell death; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0006955 immune response; GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process; GO:0006887 exocytosis; GO:0006901 vesicle coating; GO:0048207 vesicle targeting, rough ER to cis-Golgi; GO:0023051 regulation of signaling; GO:0031331 positive regulation of cellular catabolic process; GO:0044699 single-organism process; GO:0051234 establishment of localization; GO:2001233 regulation of apoptotic signaling pathway; GO:0051649 establishment of localization in cell; GO:0010646 regulation of cell communication; GO:0022607 cellular component assembly; GO:0009893 positive regulation of metabolic process; GO:0002250 adaptive immune response; GO:0006915 apoptotic process; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:0051650 establishment of vesicle localization; GO:0071822 protein complex subunit organization; GO:0002446 neutrophil mediated immunity; GO:0048522 positive regulation of cellular process; GO:0002444 myeloid leukocyte mediated immunity; GO:0010942 positive regulation of cell death; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0032940 secretion by cell; GO:0007568 aging; GO:0019222 regulation of metabolic process; GO:0043299 leukocyte degranulation; GO:0070271 protein complex biogenesis; GO:0016043 cellular component organization; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0048193 Golgi vesicle transport; GO:0043065 positive regulation of apoptotic process; GO:0006903 vesicle targeting; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0045862 positive regulation of proteolysis; GO:0023056 positive regulation of signaling; GO:0051648 vesicle localization; GO:2001235 positive regulation of apoptotic signaling pathway; GO:0006508 proteolysis; GO:0010647 positive regulation of cell communication; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0044265 cellular macromolecule catabolic process; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0016050 vesicle organization; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0043933 macromolecular complex subunit organization; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0009057 macromolecule catabolic process; GO:0045732 positive regulation of protein catabolic process; GO:0009967 positive regulation of signal transduction; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0009056 catabolic process; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0044430 cytoskeletal part; GO:0031981 nuclear lumen; GO:0030135 coated vesicle; GO:0005576 extracellular region; GO:0042582 azurophil granule; GO:0043231 intracellular membrane-bounded organelle; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0030133 transport vesicle; GO:0043230 extracellular organelle; GO:0034774 secretory granule lumen; GO:0005783 endoplasmic reticulum; GO:0005615 extracellular space; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0031983 vesicle lumen; GO:0005815 microtubule organizing center; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0030141 secretory granule; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0005788 endoplasmic reticulum lumen; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0030134 ER to Golgi transport vesicle; GO:0043226 organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0044432 endoplasmic reticulum part; GO:0005813 centrosome; GO:0005793 endoplasmic reticulum-Golgi intermediate compartment; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0008233 peptidase activity; GO:0051087 chaperone binding; GO:0043621 protein self-association; GO:0043167 ion binding; GO:0008236 serine-type peptidase activity; GO:0061134 peptidase regulator activity; GO:0016504 peptidase activator activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0008234 cysteine-type peptidase activity; GO:0098772 molecular function regulator; GO:0004252 serine-type endopeptidase activity; GO:0004175 endopeptidase activity; GO:0042802 identical protein binding; GO:0030234 enzyme regulator activity; GO:0017171 serine hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0031404 chloride ion binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0043168 anion binding; GO:0019902 phosphatase binding; GO:0004197 cysteine-type endopeptidase activity; GO:0016505 peptidase activator activity involved in apoptotic process; GO:0019899 enzyme binding; GO:0008047 enzyme activator activity; ","K01275","CTSC; cathepsin C [EC:3.4.14.1]","hsa04142 Lysosome - Homo sapiens (human); hsa04210 Apoptosis - Homo sapiens (human); ","IPR014882; IPR000668; ","\"Cathepsin C exclusion; Peptidase C1A, papain C-terminal; \"\r"]
["P53990","IST1 homolog OS=Homo sapiens OX=9606 GN=IST1","IST1",39.75,6.8709,8,3,3,3,0.991,0.926,0.952,1.104,1.058,1.002,1.103,0.0467,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0032270 positive regulation of cellular protein metabolic process; GO:0052192 movement in environment of other organism involved in symbiotic interaction; GO:0015031 protein transport; GO:0045927 positive regulation of growth; GO:0001558 regulation of cell growth; GO:0051240 positive regulation of multicellular organismal process; GO:0032535 regulation of cellular component size; GO:0036258 multivesicular body assembly; GO:0044419 interspecies interaction between organisms; GO:0008104 protein localization; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0007399 nervous system development; GO:0002443 leukocyte mediated immunity; GO:0030307 positive regulation of cell growth; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0031346 positive regulation of cell projection organization; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051301 cell division; GO:0048672 positive regulation of collateral sprouting; GO:0051094 positive regulation of developmental process; GO:0010975 regulation of neuron projection development; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0002283 neutrophil activation involved in immune response; GO:0051239 regulation of multicellular organismal process; GO:0045597 positive regulation of cell differentiation; GO:0052126 movement in host environment; GO:0000910 cytokinesis; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0050772 positive regulation of axonogenesis; GO:0007275 multicellular organism development; GO:0048731 system development; GO:0051960 regulation of nervous system development; GO:0060284 regulation of cell development; GO:0016192 vesicle-mediated transport; GO:0032984 macromolecular complex disassembly; GO:0002376 immune system process; GO:0071702 organic substance transport; GO:0030162 regulation of proteolysis; GO:0002263 cell activation involved in immune response; GO:0050770 regulation of axonogenesis; GO:0045184 establishment of protein localization; GO:0019076 viral release from host cell; GO:0045055 regulated exocytosis; GO:0035890 exit from host; GO:0051247 positive regulation of protein metabolic process; GO:0010976 positive regulation of neuron projection development; GO:0006996 organelle organization; GO:0048670 regulation of collateral sprouting; GO:0031325 positive regulation of cellular metabolic process; GO:0061387 regulation of extent of cell growth; GO:0001775 cell activation; GO:0050769 positive regulation of neurogenesis; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:0006955 immune response; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0006887 exocytosis; GO:0010256 endomembrane system organization; GO:0045666 positive regulation of neuron differentiation; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0044764 multi-organism cellular process; GO:0051234 establishment of localization; GO:0043241 protein complex disassembly; GO:0051130 positive regulation of cellular component organization; GO:0009893 positive regulation of metabolic process; GO:0022607 cellular component assembly; GO:1904896 ESCRT complex disassembly; GO:0033036 macromolecule localization; GO:0010720 positive regulation of cell development; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:0071822 protein complex subunit organization; GO:0048639 positive regulation of developmental growth; GO:0002446 neutrophil mediated immunity; GO:0051962 positive regulation of nervous system development; GO:0048522 positive regulation of cellular process; GO:0036257 multivesicular body organization; GO:0002444 myeloid leukocyte mediated immunity; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0045664 regulation of neuron differentiation; GO:0032940 secretion by cell; GO:0019222 regulation of metabolic process; GO:0046745 viral capsid secondary envelopment; GO:0043299 leukocyte degranulation; GO:0040011 locomotion; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0016043 cellular component organization; GO:0040008 regulation of growth; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0010770 positive regulation of cell morphogenesis involved in differentiation; GO:0031344 regulation of cell projection organization; GO:0050896 response to stimulus; GO:0048638 regulation of developmental growth; GO:0030154 cell differentiation; GO:0009838 abscission; GO:0045862 positive regulation of proteolysis; GO:0008361 regulation of cell size; GO:0070925 organelle assembly; GO:0016032 viral process; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0035891 exit from host cell; GO:0016050 vesicle organization; GO:0043312 neutrophil degranulation; GO:0051701 interaction with host; GO:0048518 positive regulation of biological process; GO:0043933 macromolecular complex subunit organization; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:1904903 ESCRT III complex disassembly; GO:0090066 regulation of anatomical structure size; GO:0022411 cellular component disassembly; GO:0051128 regulation of cellular component organization; GO:0022402 cell cycle process; GO:0022604 regulation of cell morphogenesis; GO:0007032 endosome organization; GO:0007049 cell cycle; GO:0050767 regulation of neurogenesis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005775 vacuolar lumen; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0005815 microtubule organizing center; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0090543 Flemming body; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0005635 nuclear envelope; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0030496 midbody; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0042582 azurophil granule; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0005813 centrosome; GO:0005766 primary lysosome; GO:0005793 endoplasmic reticulum-Golgi intermediate compartment; GO:0031975 envelope; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0050839 cell adhesion molecule binding; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0045296 cadherin binding; GO:0090541 MIT domain binding; GO:0005515 protein binding; GO:0019904 protein domain specific binding; GO:0032403 protein complex binding; ","K19476","IST1; vacuolar protein sorting-associated protein IST1","hsa04144 Endocytosis - Homo sapiens (human); "]
["P53999","Activated RNA polymerase II transcriptional coactivator p15 OS=Homo sapiens OX=9606 GN=SUB1","SUB1",14.395,34.755,37.8,5,10,5,0.916,0.864,0.894,1.088,1.113,1.084,1.228,0.000399,"nucleus\r","GO:0044700 single organism signaling; GO:0060260 regulation of transcription initiation from RNA polymerase II promoter; GO:0007166 cell surface receptor signaling pathway; GO:0097659 nucleic acid-templated transcription; GO:0009891 positive regulation of biosynthetic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0051130 positive regulation of cellular component organization; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0007154 cell communication; GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0009893 positive regulation of metabolic process; GO:2000144 positive regulation of DNA-templated transcription, initiation; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0031334 positive regulation of protein complex assembly; GO:0043170 macromolecule metabolic process; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0051716 cellular response to stimulus; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0032774 RNA biosynthetic process; GO:0023052 signaling; GO:0031323 regulation of cellular metabolic process; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0043254 regulation of protein complex assembly; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0060395 SMAD protein signal transduction; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044087 regulation of cellular component biogenesis; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0051254 positive regulation of RNA metabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:2000142 regulation of DNA-templated transcription, initiation; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006366 transcription from RNA polymerase II promoter; GO:0031325 positive regulation of cellular metabolic process; GO:0010467 gene expression; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0051128 regulation of cellular component organization; GO:0031328 positive regulation of cellular biosynthetic process; GO:0044089 positive regulation of cellular component biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0031982 vesicle; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005730 nucleolus; GO:0005667 transcription factor complex; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding; GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding; GO:0003677 DNA binding; GO:0003723 RNA binding; GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding; GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding; GO:0003697 single-stranded DNA binding; GO:0005515 protein binding; GO:0003712 transcription cofactor activity; GO:0003700 transcription factor activity, sequence-specific DNA binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0001071 nucleic acid binding transcription factor activity; GO:0000989 transcription factor activity, transcription factor binding; GO:0003713 transcription coactivator activity; GO:0000988 transcription factor activity, protein binding; ",{"$nulls":3},"IPR009044; IPR003173; ","ssDNA-binding transcriptional regulator; Transcriptional coactivator p15 (PC4); \r"]
["P54289","Voltage-dependent calcium channel subunit alpha-2/delta-1 OS=Homo sapiens OX=9606 GN=CACNA2D1","CACNA2D1",124.57,24.868,7.9,7,7,7,1.085,1.122,1.054,0.924,0.933,0.925,0.853,0.000981,"plasma membrane\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:1904427 positive regulation of calcium ion transmembrane transport; GO:0061337 cardiac conduction; GO:0098900 regulation of action potential; GO:1901019 regulation of calcium ion transmembrane transporter activity; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0060402 calcium ion transport into cytosol; GO:0055065 metal ion homeostasis; GO:0032414 positive regulation of ion transmembrane transporter activity; GO:0044057 regulation of system process; GO:0044765 single-organism transport; GO:1990035 calcium ion import into cell; GO:0044763 single-organism cellular process; GO:0043269 regulation of ion transport; GO:0006941 striated muscle contraction; GO:0098703 calcium ion import across plasma membrane; GO:0032501 multicellular organismal process; GO:0098657 import into cell; GO:0006874 cellular calcium ion homeostasis; GO:0006810 transport; GO:0034762 regulation of transmembrane transport; GO:0007267 cell-cell signaling; GO:0098739 import across plasma membrane; GO:2001257 regulation of cation channel activity; GO:1901021 positive regulation of calcium ion transmembrane transporter activity; GO:0003015 heart process; GO:0003013 circulatory system process; GO:0032412 regulation of ion transmembrane transporter activity; GO:0051899 membrane depolarization; GO:0098662 inorganic cation transmembrane transport; GO:0044707 single-multicellular organism process; GO:0034764 positive regulation of transmembrane transport; GO:0034220 ion transmembrane transport; GO:0030001 metal ion transport; GO:0051239 regulation of multicellular organismal process; GO:0086003 cardiac muscle cell contraction; GO:1902578 single-organism localization; GO:0098659 inorganic cation import into cell; GO:0010959 regulation of metal ion transport; GO:0032409 regulation of transporter activity; GO:1904062 regulation of cation transmembrane transport; GO:0048878 chemical homeostasis; GO:0051928 positive regulation of calcium ion transport; GO:0070588 calcium ion transmembrane transport; GO:0051924 regulation of calcium ion transport; GO:1902656 calcium ion import into cytosol; GO:0086048 membrane depolarization during bundle of His cell action potential; GO:1901843 positive regulation of high voltage-gated calcium channel activity; GO:2001259 positive regulation of cation channel activity; GO:0086028 bundle of His cell to Purkinje myocyte signaling; GO:0043270 positive regulation of ion transport; GO:0055085 transmembrane transport; GO:1904064 positive regulation of cation transmembrane transport; GO:0006873 cellular ion homeostasis; GO:0006811 ion transport; GO:0030029 actin filament-based process; GO:0002027 regulation of heart rate; GO:0006928 movement of cell or subcellular component; GO:0060306 regulation of membrane repolarization; GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel; GO:0051179 localization; GO:0007204 positive regulation of cytosolic calcium ion concentration; GO:0070838 divalent metal ion transport; GO:0030048 actin filament-based movement; GO:0003012 muscle system process; GO:0070252 actin-mediated cell contraction; GO:0072503 cellular divalent inorganic cation homeostasis; GO:1901841 regulation of high voltage-gated calcium channel activity; GO:0086069 bundle of His cell to Purkinje myocyte communication; GO:0044699 single-organism process; GO:0051234 establishment of localization; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0001508 action potential; GO:0060401 cytosolic calcium ion transport; GO:1901385 regulation of voltage-gated calcium channel activity; GO:0098655 cation transmembrane transport; GO:0097553 calcium ion transmembrane import into cytosol; GO:0050801 ion homeostasis; GO:0055074 calcium ion homeostasis; GO:0098771 inorganic ion homeostasis; GO:0035637 multicellular organismal signaling; GO:0019725 cellular homeostasis; GO:0098903 regulation of membrane repolarization during action potential; GO:0086010 membrane depolarization during action potential; GO:0022898 regulation of transmembrane transporter activity; GO:0023052 signaling; GO:0042391 regulation of membrane potential; GO:0051050 positive regulation of transport; GO:0050789 regulation of biological process; GO:0086001 cardiac muscle cell action potential; GO:0034767 positive regulation of ion transmembrane transport; GO:0065009 regulation of molecular function; GO:0070509 calcium ion import; GO:0099623 regulation of cardiac muscle cell membrane repolarization; GO:0072507 divalent inorganic cation homeostasis; GO:0072511 divalent inorganic cation transport; GO:0032411 positive regulation of transporter activity; GO:0030003 cellular cation homeostasis; GO:0051480 regulation of cytosolic calcium ion concentration; GO:1903522 regulation of blood circulation; GO:0008016 regulation of heart contraction; GO:0060048 cardiac muscle contraction; GO:0055082 cellular chemical homeostasis; GO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization; GO:0042592 homeostatic process; GO:1901387 positive regulation of voltage-gated calcium channel activity; GO:0006936 muscle contraction; GO:0055080 cation homeostasis; GO:0006812 cation transport; GO:0006816 calcium ion transport; GO:0086091 regulation of heart rate by cardiac conduction; GO:0086043 bundle of His cell action potential; GO:1903169 regulation of calcium ion transmembrane transport; GO:0008015 blood circulation; GO:0060047 heart contraction; GO:0009987 cellular process; GO:0099587 inorganic ion import into cell; GO:0086012 membrane depolarization during cardiac muscle cell action potential; GO:0003008 system process; GO:0098660 inorganic ion transmembrane transport; GO:0051049 regulation of transport; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0086019 cell-cell signaling involved in cardiac conduction; GO:0034765 regulation of ion transmembrane transport; GO:0086002 cardiac muscle cell action potential involved in contraction; GO:0006875 cellular metal ion homeostasis; GO:0065007 biological regulation; GO:0086065 cell communication involved in cardiac conduction; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0016528 sarcoplasm; GO:0030315 T-tubule; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0034702 ion channel complex; GO:1990351 transporter complex; GO:0043227 membrane-bounded organelle; GO:0005891 voltage-gated calcium channel complex; GO:0043229 intracellular organelle; GO:0016529 sarcoplasmic reticulum; GO:0034703 cation channel complex; GO:0012505 endomembrane system; GO:1902495 transmembrane transporter complex; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0034704 calcium channel complex; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044459 plasma membrane part; GO:1990454 L-type voltage-gated calcium channel complex; GO:0042383 sarcolemma; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005245 voltage-gated calcium channel activity; GO:0015075 ion transmembrane transporter activity; GO:0043167 ion binding; GO:0022803 passive transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0015267 channel activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0005244 voltage-gated ion channel activity; GO:0046873 metal ion transmembrane transporter activity; GO:0072509 divalent inorganic cation transmembrane transporter activity; GO:0022838 substrate-specific channel activity; GO:0005488 binding; GO:0022843 voltage-gated cation channel activity; GO:0005261 cation channel activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0015085 calcium ion transmembrane transporter activity; GO:0022836 gated channel activity; GO:0005216 ion channel activity; GO:0022890 inorganic cation transmembrane transporter activity; GO:0022832 voltage-gated channel activity; GO:0005262 calcium channel activity; GO:0008324 cation transmembrane transporter activity; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; ","K04858","CACNA2D1; voltage-dependent calcium channel alpha-2/delta-1","hsa04260 Cardiac muscle contraction - Homo sapiens (human); hsa04921 Oxytocin signaling pathway - Homo sapiens (human); hsa04010 MAPK signaling pathway - Homo sapiens (human); hsa05414 Dilated cardiomyopathy (DCM) - Homo sapiens (human); hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human); hsa05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human); hsa05410 Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human); ","IPR013680; IPR013608; IPR002035; ","\"Voltage-dependent calcium channel, alpha-2/delta subunit, conserved region; VWA N-terminal; von Willebrand factor, type A; \"\r"]
["P54577","Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS","YARS",59.143,29.557,21.4,13,17,13,0.864,0.886,0.87,1.122,1.155,1.141,1.305,1.95E-5,"cyto_nucl\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0006518 peptide metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0043039 tRNA aminoacylation; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0006520 cellular amino acid metabolic process; GO:0046483 heterocycle metabolic process; GO:0007154 cell communication; GO:0006139 nucleobase-containing compound metabolic process; GO:0006915 apoptotic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0006418 tRNA aminoacylation for protein translation; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0006412 translation; GO:0009987 cellular process; GO:0051716 cellular response to stimulus; GO:0043043 peptide biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0044238 primary metabolic process; GO:0023052 signaling; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0016070 RNA metabolic process; GO:0006399 tRNA metabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0008219 cell death; GO:0044710 single-organism metabolic process; GO:0006437 tyrosyl-tRNA aminoacylation; GO:0043038 amino acid activation; GO:0019752 carboxylic acid metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0012501 programmed cell death; GO:0043604 amide biosynthetic process; GO:0006082 organic acid metabolic process; GO:0034660 ncRNA metabolic process; GO:0043436 oxoacid metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0044446 intracellular organelle part; GO:0017102 methionyl glutamyl tRNA synthetase complex; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0016604 nuclear body; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0017101 aminoacyl-tRNA synthetase multienzyme complex; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0043234 protein complex; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds; GO:1901265 nucleoside phosphate binding; GO:0016875 ligase activity, forming carbon-oxygen bonds; GO:0005102 receptor binding; GO:0016874 ligase activity; GO:0005515 protein binding; GO:0004871 signal transducer activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0000049 tRNA binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0001664 G-protein coupled receptor binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0004831 tyrosine-tRNA ligase activity; GO:0004812 aminoacyl-tRNA ligase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003723 RNA binding; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0005126 cytokine receptor binding; GO:0000166 nucleotide binding; GO:0005153 interleukin-8 receptor binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0045236 CXCR chemokine receptor binding; GO:0003676 nucleic acid binding; GO:0042379 chemokine receptor binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; ","K01866","YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]","hsa00970 Aminoacyl-tRNA biosynthesis - Homo sapiens (human); ","IPR014729; IPR012340; IPR002547; ","\"Rossmann-like alpha/beta/alpha sandwich fold; Nucleic acid-binding, OB-fold; tRNA-binding domain; \"\r"]
["P54652","Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2","HSPA2",70.02,80.058,39.3,27,63,13,1.032,1.044,0.989,0.961,1.002,0.941,0.947,0.0942,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0000003 reproduction; GO:0016043 cellular component organization; GO:1903046 meiotic cell cycle process; GO:0022414 reproductive process; GO:0009628 response to abiotic stimulus; GO:0051129 negative regulation of cellular component organization; GO:0048285 organelle fission; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0044087 regulation of cellular component biogenesis; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0006457 protein folding; GO:0030154 cell differentiation; GO:0035966 response to topologically incorrect protein; GO:0007286 spermatid development; GO:0009408 response to heat; GO:0009266 response to temperature stimulus; GO:0044702 single organism reproductive process; GO:0007281 germ cell development; GO:0007140 male meiosis; GO:0009987 cellular process; GO:0032502 developmental process; GO:0006986 response to unfolded protein; GO:0003006 developmental process involved in reproduction; GO:0006950 response to stress; GO:0048232 male gamete generation; GO:0007283 spermatogenesis; GO:0019953 sexual reproduction; GO:0044763 single-organism cellular process; GO:0051321 meiotic cell cycle; GO:0010033 response to organic substance; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0007276 gamete generation; GO:0032504 multicellular organism reproduction; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0009409 response to cold; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0044703 multi-organism reproductive process; GO:0022412 cellular process involved in reproduction in multicellular organism; GO:0000280 nuclear division; GO:0048515 spermatid differentiation; GO:0090083 regulation of inclusion body assembly; GO:0007126 meiotic nuclear division; GO:0051128 regulation of cellular component organization; GO:0022402 cell cycle process; GO:0048856 anatomical structure development; GO:0048609 multicellular organismal reproductive process; GO:0042026 protein refolding; GO:0090084 negative regulation of inclusion body assembly; GO:0007049 cell cycle; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005856 cytoskeleton; GO:0015630 microtubule cytoskeleton; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0034702 ion channel complex; GO:1990351 transporter complex; GO:0043227 membrane-bounded organelle; GO:0005891 voltage-gated calcium channel complex; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0034703 cation channel complex; GO:0005829 cytosol; GO:1902495 transmembrane transporter complex; GO:0005576 extracellular region; GO:0005819 spindle; GO:0016021 integral component of membrane; GO:0034704 calcium channel complex; GO:0005886 plasma membrane; GO:0036128 CatSper complex; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0072562 blood microparticle; GO:0072687 meiotic spindle; GO:0044459 plasma membrane part; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0051082 unfolded protein binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0019899 enzyme binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K03283","HSPA1s; heat shock 70kDa protein 1/2/6/8","hsa03040 Spliceosome - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); hsa05020 Prion diseases - Homo sapiens (human); hsa05162 Measles - Homo sapiens (human); hsa05134 Legionellosis - Homo sapiens (human); hsa04010 MAPK signaling pathway - Homo sapiens (human); hsa04144 Endocytosis - Homo sapiens (human); hsa04612 Antigen processing and presentation - Homo sapiens (human); hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); hsa04213 Longevity regulating pathway - multiple species - Homo sapiens (human); hsa04915 Estrogen signaling pathway - Homo sapiens (human); hsa05145 Toxoplasmosis - Homo sapiens (human); hsa05164 Influenza A - Homo sapiens (human); ","IPR029048; IPR029047; ","\"Heat shock protein 70kD, C-terminal domain; Heat shock protein 70kD, peptide-binding domain; \"\r"]
["P54727","UV excision repair protein RAD23 homolog B OS=Homo sapiens OX=9606 GN=RAD23B","RAD23B",43.171,17.414,21,7,17,5,1.011,1.026,0.995,0.983,1.014,1.013,0.993,0.617,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0070646 protein modification by small protein removal; GO:0022414 reproductive process; GO:0006289 nucleotide-excision repair; GO:0032392 DNA geometric change; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006457 protein folding; GO:0008152 metabolic process; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0044702 single organism reproductive process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0009790 embryo development; GO:1903362 regulation of cellular protein catabolic process; GO:0071824 protein-DNA complex subunit organization; GO:0071103 DNA conformation change; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0019953 sexual reproduction; GO:1901360 organic cyclic compound metabolic process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0065004 protein-DNA complex assembly; GO:1901575 organic substance catabolic process; GO:0000715 nucleotide-excision repair, DNA damage recognition; GO:0048513 animal organ development; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0030163 protein catabolic process; GO:0061136 regulation of proteasomal protein catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006464 cellular protein modification process; GO:0036211 protein modification process; GO:0048609 multicellular organismal reproductive process; GO:0048856 anatomical structure development; GO:0000003 reproduction; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0006259 DNA metabolic process; GO:0048568 embryonic organ development; GO:0044267 cellular protein metabolic process; GO:0050896 response to stimulus; GO:0016579 protein deubiquitination; GO:0010498 proteasomal protein catabolic process; GO:0071704 organic substance metabolic process; GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0070911 global genome nucleotide-excision repair; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0006508 proteolysis; GO:0042176 regulation of protein catabolic process; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0043632 modification-dependent macromolecule catabolic process; GO:0034622 cellular macromolecular complex assembly; GO:0044265 cellular macromolecule catabolic process; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0006950 response to stress; GO:0048232 male gamete generation; GO:0019941 modification-dependent protein catabolic process; GO:0000717 nucleotide-excision repair, DNA duplex unwinding; GO:0032508 DNA duplex unwinding; GO:0048731 system development; GO:0007283 spermatogenesis; GO:0006807 nitrogen compound metabolic process; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0006974 cellular response to DNA damage stimulus; GO:0007276 gamete generation; GO:0043933 macromolecular complex subunit organization; GO:0032504 multicellular organism reproduction; GO:0006281 DNA repair; GO:0051276 chromosome organization; GO:0051246 regulation of protein metabolic process; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0009057 macromolecule catabolic process; GO:0044703 multi-organism reproductive process; GO:0006294 nucleotide-excision repair, preincision complex assembly; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0043412 macromolecule modification; GO:0009056 catabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0000502 proteasome complex; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:1990391 DNA repair complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:1905369 endopeptidase complex; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1905368 peptidase complex; GO:0043227 membrane-bounded organelle; GO:0043234 protein complex; GO:0000109 nucleotide-excision repair complex; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0071942 XPC complex; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003677 DNA binding; GO:0031593 polyubiquitin binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0003697 single-stranded DNA binding; GO:0043130 ubiquitin binding; GO:0003684 damaged DNA binding; GO:0005515 protein binding; GO:0032182 ubiquitin-like protein binding; ","K10839","RAD23; UV excision repair protein RAD23","hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); hsa03420 Nucleotide excision repair - Homo sapiens (human); ","IPR006636; IPR015940; IPR029071; IPR000626; IPR015360; IPR009060; ","Heat shock chaperonin-binding; Ubiquitin-associated domain; Ubiquitin-related domain; Ubiquitin domain; XPC-binding domain; UBA-like; \r"]
["P54793","Arylsulfatase F OS=Homo sapiens OX=9606 GN=ARSF","ARSF",65.939,5.0522,1.9,1,2,1,0.789,0.8,0.763,1.185,1.172,1.272,1.543,1.21E-4,"plasma membrane\r","GO:0043687 post-translational protein modification; GO:1903509 liposaccharide metabolic process; GO:0006643 membrane lipid metabolic process; GO:0006687 glycosphingolipid metabolic process; GO:0006664 glycolipid metabolic process; GO:0044763 single-organism cellular process; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0006807 nitrogen compound metabolic process; GO:0044255 cellular lipid metabolic process; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0006665 sphingolipid metabolic process; GO:0006464 cellular protein modification process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:0009987 cellular process; GO:0006629 lipid metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0005788 endoplasmic reticulum lumen; GO:0043229 intracellular organelle; GO:0005783 endoplasmic reticulum; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0070013 intracellular organelle lumen; GO:0044432 endoplasmic reticulum part; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0004065 arylsulfatase activity; GO:0008484 sulfuric ester hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0016787 hydrolase activity; ","K12374",null,null,"IPR017849; IPR000917; IPR017850; ","\"Alkaline phosphatase-like, alpha/beta/alpha; Sulfatase, N-terminal; Alkaline-phosphatase-like, core domain; \"\r"]
["P54802","Alpha-N-acetylglucosaminidase OS=Homo sapiens OX=9606 GN=NAGLU","NAGLU",82.265,15.915,7.5,4,4,4,1.02,1.031,1.056,0.929,0.956,0.941,0.91,1.98E-3,"extracellular\r","GO:0060113 inner ear receptor cell differentiation; GO:0007420 brain development; GO:0006026 aminoglycan catabolic process; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0042474 middle ear morphogenesis; GO:0030203 glycosaminoglycan metabolic process; GO:0007622 rhythmic behavior; GO:0007610 behavior; GO:0008152 metabolic process; GO:0048562 embryonic organ morphogenesis; GO:0060322 head development; GO:0007033 vacuole organization; GO:0043170 macromolecule metabolic process; GO:0042461 photoreceptor cell development; GO:0045475 locomotor rhythm; GO:0009790 embryo development; GO:0048512 circadian behavior; GO:0048598 embryonic morphogenesis; GO:0042462 eye photoreceptor cell development; GO:0090596 sensory organ morphogenesis; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0048592 eye morphogenesis; GO:0048699 generation of neurons; GO:0046530 photoreceptor cell differentiation; GO:0044763 single-organism cellular process; GO:0032501 multicellular organismal process; GO:0006027 glycosaminoglycan catabolic process; GO:0007040 lysosome organization; GO:0007623 circadian rhythm; GO:0021549 cerebellum development; GO:1901575 organic substance catabolic process; GO:0021680 cerebellar Purkinje cell layer development; GO:0048513 animal organ development; GO:0043583 ear development; GO:0007417 central nervous system development; GO:0009887 animal organ morphogenesis; GO:0022037 metencephalon development; GO:0021695 cerebellar cortex development; GO:0048856 anatomical structure development; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0048568 embryonic organ development; GO:0048468 cell development; GO:0071704 organic substance metabolic process; GO:0046548 retinal rod cell development; GO:0009653 anatomical structure morphogenesis; GO:0001654 eye development; GO:0030154 cell differentiation; GO:1901135 carbohydrate derivative metabolic process; GO:0007275 multicellular organism development; GO:0006022 aminoglycan metabolic process; GO:0009987 cellular process; GO:0030902 hindbrain development; GO:0001754 eye photoreceptor cell differentiation; GO:0048731 system development; GO:0042490 mechanoreceptor differentiation; GO:1901136 carbohydrate derivative catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0048839 inner ear development; GO:0030182 neuron differentiation; GO:1901565 organonitrogen compound catabolic process; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0048511 rhythmic process; GO:0009057 macromolecule catabolic process; GO:0042471 ear morphogenesis; GO:0080171 lytic vacuole organization; GO:0007626 locomotory behavior; GO:0060119 inner ear receptor cell development; GO:0007423 sensory organ development; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; GO:1901564 organonitrogen compound metabolic process; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0043202 lysosomal lumen; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0044437 vacuolar part; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0005773 vacuole; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0000323 lytic vacuole; ","GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds; GO:0004561 alpha-N-acetylglucosaminidase activity; GO:0016787 hydrolase activity; GO:0003824 catalytic activity; GO:0016798 hydrolase activity, acting on glycosyl bonds; GO:0015929 hexosaminidase activity; ","K01205","NAGLU; alpha-N-acetylglucosaminidase [EC:3.2.1.50]","hsa04142 Lysosome - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00531 Glycosaminoglycan degradation - Homo sapiens (human); ","IPR024733; IPR024240; IPR024732; IPR017853; ","\"Alpha-N-acetylglucosaminidase, tim-barrel domain; Alpha-N-acetylglucosaminidase, N-terminal; Alpha-N-acetylglucosaminidase, C-terminal; Glycoside hydrolase superfamily; \"\r"]
["P54920","Alpha-soluble NSF attachment protein OS=Homo sapiens OX=9606 GN=NAPA","NAPA",33.232,86.935,51.9,13,24,13,0.971,1.002,0.899,1.041,1.037,1.041,1.086,0.122,"cytoplasm\r","GO:0044700 single organism signaling; GO:0060627 regulation of vesicle-mediated transport; GO:0044085 cellular component biogenesis; GO:0001505 regulation of neurotransmitter levels; GO:0006901 vesicle coating; GO:0065008 regulation of biological quality; GO:0048207 vesicle targeting, rough ER to cis-Golgi; GO:0048208 COPII vesicle coating; GO:0007420 brain development; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:0022008 neurogenesis; GO:0051046 regulation of secretion; GO:0044699 single-organism process; GO:0007270 neuron-neuron synaptic transmission; GO:0015031 protein transport; GO:0043241 protein complex disassembly; GO:0051234 establishment of localization; GO:0008105 asymmetric protein localization; GO:0010646 regulation of cell communication; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0032879 regulation of localization; GO:0065003 macromolecular complex assembly; GO:0048199 vesicle targeting, to, from or within Golgi; GO:0060322 head development; GO:0098916 anterograde trans-synaptic signaling; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0051650 establishment of vesicle localization; GO:0071822 protein complex subunit organization; GO:0048699 generation of neurons; GO:0006891 intra-Golgi vesicle-mediated transport; GO:0045176 apical protein localization; GO:0044763 single-organism cellular process; GO:0061025 membrane fusion; GO:0032386 regulation of intracellular transport; GO:0023052 signaling; GO:1903530 regulation of secretion by cell; GO:0046928 regulation of neurotransmitter secretion; GO:0032501 multicellular organismal process; GO:1902803 regulation of synaptic vesicle transport; GO:0006810 transport; GO:0048513 animal organ development; GO:0043254 regulation of protein complex assembly; GO:0050789 regulation of biological process; GO:0007267 cell-cell signaling; GO:0007417 central nervous system development; GO:0070271 protein complex biogenesis; GO:0048856 anatomical structure development; GO:0051640 organelle localization; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0044707 single-multicellular organism process; GO:0035494 SNARE complex disassembly; GO:0017157 regulation of exocytosis; GO:0048193 Golgi vesicle transport; GO:0044087 regulation of cellular component biogenesis; GO:0010807 regulation of synaptic vesicle priming; GO:0006903 vesicle targeting; GO:0060341 regulation of cellular localization; GO:2000300 regulation of synaptic vesicle exocytosis; GO:0030154 cell differentiation; GO:0051648 vesicle localization; GO:0006886 intracellular protein transport; GO:0099537 trans-synaptic signaling; GO:0043624 cellular protein complex disassembly; GO:0035249 synaptic transmission, glutamatergic; GO:0007275 multicellular organism development; GO:0034613 cellular protein localization; GO:0051588 regulation of neurotransmitter transport; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0090114 COPII-coated vesicle budding; GO:0048731 system development; GO:0051049 regulation of transport; GO:0050804 modulation of synaptic transmission; GO:0016192 vesicle-mediated transport; GO:0032984 macromolecular complex disassembly; GO:0016050 vesicle organization; GO:0071702 organic substance transport; GO:1903305 regulation of regulated secretory pathway; GO:0051656 establishment of organelle localization; GO:0043933 macromolecular complex subunit organization; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0030182 neuron differentiation; GO:0070727 cellular macromolecule localization; GO:0099536 synaptic signaling; GO:0006890 retrograde vesicle-mediated transport, Golgi to ER; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0061024 membrane organization; GO:0006900 membrane budding; GO:0022411 cellular component disassembly; GO:0051128 regulation of cellular component organization; GO:0007268 chemical synaptic transmission; GO:0051179 localization; GO:0017158 regulation of calcium ion-dependent exocytosis; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0043679 axon terminus; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0098793 presynapse; GO:0043209 myelin sheath; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0044431 Golgi apparatus part; GO:0044306 neuron projection terminus; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0031201 SNARE complex; GO:0044456 synapse part; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0044463 cell projection part; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0033267 axon part; GO:0045202 synapse; GO:0030424 axon; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044437 vacuolar part; GO:0043195 terminal bouton; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0043234 protein complex; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0000149 SNARE binding; GO:0005483 soluble NSF attachment protein activity; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0005515 protein binding; GO:0019905 syntaxin binding; GO:0032403 protein complex binding; ","K15296","NAPA; alpha-soluble NSF attachment protein","hsa04721 Synaptic vesicle cycle - Homo sapiens (human); ","IPR011990; ","Tetratricopeptide-like helical domain; \r"]
["P55001","Microfibrillar-associated protein 2 OS=Homo sapiens OX=9606 GN=MFAP2","MFAP2",20.825,7.8075,12,2,5,2,1.272,1.281,1.187,0.749,0.724,0.81,0.61,0.000278,"extracellular\r","GO:0032502 developmental process; GO:0048569 post-embryonic animal organ development; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0048568 embryonic organ development; GO:0048731 system development; GO:0048592 eye morphogenesis; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0009791 post-embryonic development; GO:0032501 multicellular organismal process; GO:0009886 post-embryonic animal morphogenesis; GO:0009653 anatomical structure morphogenesis; GO:0001654 eye development; GO:0048513 animal organ development; GO:0048562 embryonic organ morphogenesis; GO:0043062 extracellular structure organization; GO:0044767 single-organism developmental process; GO:0009887 animal organ morphogenesis; GO:0048050 post-embryonic eye morphogenesis; GO:0030198 extracellular matrix organization; GO:0048048 embryonic eye morphogenesis; GO:0048563 post-embryonic animal organ morphogenesis; GO:0007275 multicellular organism development; GO:0009790 embryo development; GO:0007423 sensory organ development; GO:0009987 cellular process; GO:0048856 anatomical structure development; GO:0048598 embryonic morphogenesis; GO:0090596 sensory organ morphogenesis; GO:0071840 cellular component organization or biogenesis; ","GO:0031012 extracellular matrix; GO:0044421 extracellular region part; GO:0005578 proteinaceous extracellular matrix; GO:0099512 supramolecular fiber; GO:0001527 microfibril; GO:0099080 supramolecular complex; GO:0044420 extracellular matrix component; GO:0005576 extracellular region; GO:0099081 supramolecular polymer; ",{"$nulls":4},"IPR003582; ","ShKT domain; \r"]
["P55011","Solute carrier family 12 member 2 OS=Homo sapiens OX=9606 GN=SLC12A2","SLC12A2",131.45,100.77,18.6,18,31,18,1.112,1.184,1.177,0.869,0.82,0.854,0.732,0.000297,"plasma membrane\r","GO:0098661 inorganic anion transmembrane transport; GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0016043 cellular component organization; GO:0065008 regulation of biological quality; GO:0034220 ion transmembrane transport; GO:0007214 gamma-aminobutyric acid signaling pathway; GO:0030001 metal ion transport; GO:0009628 response to abiotic stimulus; GO:0044699 single-organism process; GO:0072488 ammonium transmembrane transport; GO:0006821 chloride transport; GO:0050896 response to stimulus; GO:0098656 anion transmembrane transport; GO:1902476 chloride transmembrane transport; GO:0051234 establishment of localization; GO:0006884 cell volume homeostasis; GO:0042592 homeostatic process; GO:0006813 potassium ion transport; GO:0007165 signal transduction; GO:0008361 regulation of cell size; GO:0007154 cell communication; GO:1902578 single-organism localization; GO:0006812 cation transport; GO:0070633 transepithelial transport; GO:0032535 regulation of cellular component size; GO:0009987 cellular process; GO:0044765 single-organism transport; GO:0032502 developmental process; GO:0030321 transepithelial chloride transport; GO:0051716 cellular response to stimulus; GO:0098655 cation transmembrane transport; GO:0006970 response to osmotic stress; GO:0006950 response to stress; GO:0098660 inorganic ion transmembrane transport; GO:0015696 ammonium transport; GO:0044763 single-organism cellular process; GO:0006972 hyperosmotic response; GO:0019725 cellular homeostasis; GO:0070634 transepithelial ammonium transport; GO:0023052 signaling; GO:0006814 sodium ion transport; GO:0007186 G-protein coupled receptor signaling pathway; GO:0006810 transport; GO:0006820 anion transport; GO:0055085 transmembrane transport; GO:0050789 regulation of biological process; GO:0044767 single-organism developmental process; GO:0006811 ion transport; GO:0007568 aging; GO:0045795 positive regulation of cell volume; GO:0090066 regulation of anatomical structure size; GO:0051179 localization; GO:0015672 monovalent inorganic cation transport; GO:0015698 inorganic anion transport; GO:0071705 nitrogen compound transport; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031226 intrinsic component of plasma membrane; GO:0016324 apical plasma membrane; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0098590 plasma membrane region; GO:0044464 cell part; GO:0044425 membrane part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0045177 apical part of cell; ","GO:0015294 solute:cation symporter activity; GO:0022804 active transmembrane transporter activity; GO:0015291 secondary active transmembrane transporter activity; GO:0008519 ammonium transmembrane transporter activity; GO:0015075 ion transmembrane transporter activity; GO:0022853 active ion transmembrane transporter activity; GO:0015293 symporter activity; GO:0019901 protein kinase binding; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0019900 kinase binding; GO:0015103 inorganic anion transmembrane transporter activity; GO:0015377 cation:chloride symporter activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0015108 chloride transmembrane transporter activity; GO:0008511 sodium:potassium:chloride symporter activity; GO:0005488 binding; GO:0015296 anion:cation symporter activity; GO:0008324 cation transmembrane transporter activity; GO:0019899 enzyme binding; GO:0008509 anion transmembrane transporter activity; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; ","K10951","SLC12A2; solute carrier family 12 (sodium/potassium/chloride transporter), member 2","hsa05110 Vibrio cholerae infection - Homo sapiens (human); hsa04972 Pancreatic secretion - Homo sapiens (human); hsa04970 Salivary secretion - Homo sapiens (human); ","IPR013612; IPR018491; IPR004841; ","\"Amino acid permease, N-terminal; SLC12A transporter, C-terminal; Amino acid permease/ SLC12A domain; \"\r"]
["P55056","Apolipoprotein C-IV OS=Homo sapiens OX=9606 GN=APOC4","APOC4",14.553,3.2506,12.6,2,2,2,0.946,0.833,0.803,1.154,1.089,1.167,1.321,6.6E-3,"extracellular\r","GO:0065008 regulation of biological quality; GO:0010889 regulation of sequestering of triglyceride; GO:0044699 single-organism process; GO:0070328 triglyceride homeostasis; GO:0042157 lipoprotein metabolic process; GO:0071704 organic substance metabolic process; GO:0051234 establishment of localization; GO:0042592 homeostatic process; GO:0008152 metabolic process; GO:1902578 single-organism localization; GO:0032879 regulation of localization; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0033036 macromolecule localization; GO:0055088 lipid homeostasis; GO:0048878 chemical homeostasis; GO:0006629 lipid metabolic process; GO:0044765 single-organism transport; GO:0010890 positive regulation of sequestering of triglyceride; GO:0006869 lipid transport; GO:0010884 positive regulation of lipid storage; GO:0010876 lipid localization; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0010883 regulation of lipid storage; GO:0055090 acylglycerol homeostasis; GO:0044710 single-organism metabolic process; GO:0051179 localization; GO:0065007 biological regulation; ","GO:0044421 extracellular region part; GO:0005615 extracellular space; GO:0032994 protein-lipid complex; GO:1990777 lipoprotein particle; GO:0034358 plasma lipoprotein particle; GO:0034385 triglyceride-rich plasma lipoprotein particle; GO:0032991 macromolecular complex; GO:0034364 high-density lipoprotein particle; GO:0005576 extracellular region; GO:0034361 very-low-density lipoprotein particle; ","GO:0005319 lipid transporter activity; GO:0022892 substrate-specific transporter activity; GO:0005215 transporter activity; "]
["P55072","Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP","VCP",89.321,299.24,54.6,40,86,40,0.958,0.958,0.926,1.051,1.046,1.081,1.118,0.00186,"cyto_nucl\r",{"$cut":{"chars":16467,"head":"GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0009891 positive regulation of biosynthetic process; GO:0018196 peptidyl-asparagine modification; GO:0006914 autophagy; GO:0044237 cellular metabolic process; GO:1903364 positive regulation of cellular protein catabolic process; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0065003 macromolecular complex assembly; GO:0044093 positive regulation of molecular function; GO:0019693 ribose phosphate metabolic process; GO:0019985 translesion synthesis; GO:0052548 regulation of endopeptidase activity; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0010950 positive regulation of endopeptidase activity; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0051704 multi-organism process; GO:0006810 transport; GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0019439 aromatic compound catabolic process; GO:1901575 organic substance catabolic process; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0019674 NAD metabolic process; GO:0030163 protein catabolic process; GO:0061136 regulation of proteasomal protein catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0045981 positive regulation of nucleotide metabolic process; GO:0042728 flavin-containing compound catabolic process; GO:2001056 positive regulation of cysteine-type endopeptidase activity; GO:0009259 ribonucleotide metabolic process; GO:0006259 DNA metabolic process; GO:0070841 inclusion body assembly; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0051345 positive regulation of hydrolase activity; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0009896 positive regulation of catabolic process; GO:0070987 error-free translesion synthesis; GO:0044248 cellular catabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0042176 regulation of protein catabolic process; GO:0034613 cellular protein localization; GO:0045838 positive regulation of membrane potential; GO:0006986 response to unfolded protein; GO:0032527 protein exit from endoplasmic reticulum; GO:0016567 protein ubiquitination; GO:0006950 response to stress; GO:0002376 immune system process; GO:0009141 nucleoside triphosphate metabolic process; GO:0048284 organelle fusion; GO:0010033 response to organic substance; GO:0002263 cell activation involved in immune response; GO:1901576 organic substance biosynthetic process; GO:0006163 purine nucleotide metabolic process; GO:0006974 cellular response to DNA damage stimulus; GO:0045055 regulated exocytosis; GO:0032446 protein modification by small protein conjugation; GO:0097576 vacuole fusion; GO:0043414 macromolecule methylation; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0019637 organophosphate metabolic process; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0006955 immune response; GO:0043412 macromolecule modification; GO:0072387 flavin adenine dinucleotide metabolic process; GO:0043467 regulation of generation of precursor metabolites and energy; GO:0070646 protein modification by small protein removal; GO:0031331 positive regulation of cellular catabolic process; GO:0010918 positive regulation of mitochondrial membrane potential; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0072524 pyridine-containing compound metabolic process; GO:0032259 methylation; GO:0006796 phosphate-containing compound metabolic process; GO:0030968 endoplasmic reticulum unfolded protein response; GO:0007165 signal transduction; GO:0071712 ER-associ"}},"GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0005654 nucleoplasm; GO:0043209 myelin sheath; GO:0005622 intracellular; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:1905368 peptidase complex; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0000502 proteasome complex; GO:0031981 nuclear lumen; GO:0005576 extracellular region; GO:0090734 site of DNA damage; GO:0042582 azurophil granule; GO:1990730 VCP-NSFL1C complex; GO:0043231 intracellular membrane-bounded organelle; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0034774 secretory granule lumen; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex; GO:0044424 intracellular part; GO:0044427 chromosomal part; GO:1905369 endopeptidase complex; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0044425 membrane part; GO:0005694 chromosome; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0030141 secretory granule; GO:0005811 lipid particle; GO:0036513 Derlin-1 retrotranslocation complex; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0043226 organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0044432 endoplasmic reticulum part; GO:0035861 site of double-strand break; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0019903 protein phosphatase binding; GO:0031625 ubiquitin protein ligase binding; GO:0005102 receptor binding; GO:0061134 peptidase regulator activity; GO:0016504 peptidase activator activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0035800 deubiquitinase activator activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0042288 MHC class I protein binding; GO:0032182 ubiquitin-like protein binding; GO:0016887 ATPase activity; GO:0036435 K48-linked polyubiquitin binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:1990381 ubiquitin-specific protease binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0008289 lipid binding; GO:0042287 MHC protein binding; GO:0043531 ADP binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0019902 phosphatase binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0008047 enzyme activator activity; GO:0035639 purine ribonucleoside triphosphate binding; GO:0017076 purine nucleotide binding; GO:0003723 RNA binding; GO:0031593 polyubiquitin binding; GO:0005524 ATP binding; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:1904288 BAT3 complex binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0002020 protease binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0030234 enzyme regulator activity; GO:0003676 nucleic acid binding; GO:0043130 ubiquitin binding; GO:0019904 protein domain specific binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0019899 enzyme binding; GO:0032403 protein complex binding; GO:0036094 small molecule binding; ","K13525","VCP; transitional endoplasmic reticulum ATPase","hsa05134 Legionellosis - Homo sapiens (human); hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); ","IPR029067; IPR003593; IPR003959; IPR009010; IPR015415; IPR004201; IPR027417; IPR003338; ","\"CDC48 domain 2-like; AAA+ ATPase domain; ATPase, AAA-type, core; Aspartate decarboxylase-like domain; Vps4 oligomerisation, C-terminal; CDC48, domain 2; P-loop containing nucleoside triphosphate hydrolase; CDC48, N-terminal subdomain; \"\r"]
["P55083","Microfibril-associated glycoprotein 4 OS=Homo sapiens OX=9606 GN=MFAP4","MFAP4",28.648,42.943,9.8,2,19,2,1.154,1.086,1.119,0.876,0.922,0.876,0.796,0.000738,"extracellular\r","GO:0044085 cellular component biogenesis; GO:0016043 cellular component organization; GO:0044246 regulation of multicellular organismal metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0048251 elastic fiber assembly; GO:0009628 response to abiotic stimulus; GO:0034644 cellular response to UV; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:0071493 cellular response to UV-B; GO:0022610 biological adhesion; GO:0022607 cellular component assembly; GO:0043062 extracellular structure organization; GO:0007155 cell adhesion; GO:0009314 response to radiation; GO:0030198 extracellular matrix organization; GO:0071478 cellular response to radiation; GO:0009987 cellular process; GO:0051716 cellular response to stimulus; GO:0009416 response to light stimulus; GO:0071214 cellular response to abiotic stimulus; GO:0044763 single-organism cellular process; GO:0085029 extracellular matrix assembly; GO:0009650 UV protection; GO:0071482 cellular response to light stimulus; GO:0009411 response to UV; GO:0050789 regulation of biological process; GO:0010224 response to UV-B; GO:0019222 regulation of metabolic process; GO:0097435 supramolecular fiber organization; GO:0010712 regulation of collagen metabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0099512 supramolecular fiber; GO:0071953 elastic fiber; GO:0099080 supramolecular complex; GO:0001527 microfibril; GO:0044420 extracellular matrix component; GO:0005576 extracellular region; GO:0099081 supramolecular polymer; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0031012 extracellular matrix; GO:1903561 extracellular vesicle; GO:0005578 proteinaceous extracellular matrix; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR002181; IPR014716; IPR014715; ","\"Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain; Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1; Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2; \"\r"]
["P55209","Nucleosome assembly protein 1-like 1 OS=Homo sapiens OX=9606 GN=NAP1L1","NAP1L1",45.374,71.212,19.2,5,9,4,1.029,0.89,0.974,0.996,1.052,1.058,1.074,0.194,"cyto_nucl\r","GO:0050794 regulation of cellular process; GO:0044085 cellular component biogenesis; GO:0016043 cellular component organization; GO:0034728 nucleosome organization; GO:0006260 DNA replication; GO:0042127 regulation of cell proliferation; GO:0006725 cellular aromatic compound metabolic process; GO:0006259 DNA metabolic process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0006323 DNA packaging; GO:0008152 metabolic process; GO:0006334 nucleosome assembly; GO:0046483 heterocycle metabolic process; GO:0022607 cellular component assembly; GO:0006139 nucleobase-containing compound metabolic process; GO:0065003 macromolecular complex assembly; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0031497 chromatin assembly; GO:0009987 cellular process; GO:0071824 protein-DNA complex subunit organization; GO:0071103 DNA conformation change; GO:0006333 chromatin assembly or disassembly; GO:0034622 cellular macromolecular complex assembly; GO:0048522 positive regulation of cellular process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0065004 protein-DNA complex assembly; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0051276 chromosome organization; GO:0006996 organelle organization; GO:0044260 cellular macromolecule metabolic process; GO:0006325 chromatin organization; GO:0008284 positive regulation of cell proliferation; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0031410 cytoplasmic vesicle; GO:0042470 melanosome; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0048770 pigment granule; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005515 protein binding; GO:0005488 binding; GO:0003676 nucleic acid binding; ","K11279"]
["P55210","Caspase-7 OS=Homo sapiens OX=9606 GN=CASP7","CASP7",34.276,29.893,9.9,2,2,2,1.15,0.896,0.702,1.008,1.221,1.025,1.184,0.298,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0010941 regulation of cell death; GO:0032270 positive regulation of cellular protein metabolic process; GO:2001056 positive regulation of cysteine-type endopeptidase activity; GO:0060255 regulation of macromolecule metabolic process; GO:0043067 regulation of programmed cell death; GO:0043065 positive regulation of apoptotic process; GO:0044699 single-organism process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0045862 positive regulation of proteolysis; GO:0009893 positive regulation of metabolic process; GO:0051345 positive regulation of hydrolase activity; GO:0044093 positive regulation of molecular function; GO:0006915 apoptotic process; GO:0006508 proteolysis; GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0009987 cellular process; GO:0052548 regulation of endopeptidase activity; GO:0010950 positive regulation of endopeptidase activity; GO:2000116 regulation of cysteine-type endopeptidase activity; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0030162 regulation of proteolysis; GO:0031323 regulation of cellular metabolic process; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0010942 positive regulation of cell death; GO:0043085 positive regulation of catalytic activity; GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0051247 positive regulation of protein metabolic process; GO:0051336 regulation of hydrolase activity; GO:0008219 cell death; GO:0050790 regulation of catalytic activity; GO:0051246 regulation of protein metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0097194 execution phase of apoptosis; GO:0012501 programmed cell death; GO:0052547 regulation of peptidase activity; GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; GO:0010952 positive regulation of peptidase activity; GO:0042981 regulation of apoptotic process; GO:0043068 positive regulation of programmed cell death; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0004175 endopeptidase activity; GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process; GO:0008233 peptidase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0016787 hydrolase activity; GO:0008234 cysteine-type peptidase activity; GO:0005515 protein binding; GO:0004197 cysteine-type endopeptidase activity; GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis; ","K04397","CASP7; caspase 7 [EC:3.4.22.60]","hsa05010 Alzheimer's disease - Homo sapiens (human); hsa05134 Legionellosis - Homo sapiens (human); hsa05133 Pertussis - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa04210 Apoptosis - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa04215 Apoptosis - multiple species - Homo sapiens (human); hsa04668 TNF signaling pathway - Homo sapiens (human); ","IPR029030; IPR001309; IPR015917; IPR002138; ","\"Caspase-like domain; Peptidase C14,  p20 domain; Peptidase C14A, caspase catalytic domain; Peptidase C14, caspase non-catalytic subunit p10; \"\r"]
["P55268","Laminin subunit beta-2 OS=Homo sapiens OX=9606 GN=LAMB2","LAMB2",195.98,272.35,24.7,32,44,32,1.119,1.095,1.167,0.876,0.853,0.896,0.776,0.000421,"extracellular\r","GO:0007528 neuromuscular junction development; GO:0007601 visual perception; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0014037 Schwann cell differentiation; GO:0032989 cellular component morphogenesis; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0014044 Schwann cell development; GO:0050877 neurological system process; GO:0009611 response to wounding; GO:0022610 biological adhesion; GO:0009605 response to external stimulus; GO:0032990 cell part morphogenesis; GO:0048677 axon extension involved in regeneration; GO:0072207 metanephric epithelium development; GO:0007155 cell adhesion; GO:0048858 cell projection morphogenesis; GO:0072015 glomerular visceral epithelial cell development; GO:0030198 extracellular matrix organization; GO:0072202 cell differentiation involved in metanephros development; GO:0007422 peripheral nervous system development; GO:0061318 renal filtration cell differentiation; GO:0072312 metanephric glomerular epithelial cell differentiation; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0072274 metanephric glomerular basement membrane development; GO:0048675 axon extension; GO:0051716 cellular response to stimulus; GO:0060429 epithelium development; GO:0002064 epithelial cell development; GO:0072244 metanephric glomerular epithelium development; GO:0007600 sensory perception; GO:0032836 glomerular basement membrane development; GO:0009888 tissue development; GO:0016049 cell growth; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0048812 neuron projection morphogenesis; GO:0031102 neuron projection regeneration; GO:0006935 chemotaxis; GO:0032501 multicellular organismal process; GO:0000902 cell morphogenesis; GO:0072310 glomerular epithelial cell development; GO:0001656 metanephros development; GO:0072313 metanephric glomerular epithelial cell development; GO:0001655 urogenital system development; GO:0048513 animal organ development; GO:0042221 response to chemical; GO:0042063 gliogenesis; GO:0030030 cell projection organization; GO:0007417 central nervous system development; GO:0021782 glial cell development; GO:0072010 glomerular epithelium development; GO:0048708 astrocyte differentiation; GO:0042330 taxis; GO:0040011 locomotion; GO:0072112 glomerular visceral epithelial cell differentiation; GO:0048856 anatomical structure development; GO:0048682 sprouting of injured axon; GO:0030855 epithelial cell differentiation; GO:0033554 cellular response to stress; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0043010 camera-type eye development; GO:0014002 astrocyte development; GO:1990138 neuron projection extension; GO:0072001 renal system development; GO:0050896 response to stimulus; GO:0007411 axon guidance; GO:0048468 cell development; GO:0000904 cell morphogenesis involved in differentiation; GO:0032835 glomerulus development; GO:0031103 axon regeneration; GO:0009653 anatomical structure morphogenesis; GO:0001654 eye development; GO:0030154 cell differentiation; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0043062 extracellular structure organization; GO:0007409 axonogenesis; GO:0072006 nephron development; GO:0007275 multicellular organism development; GO:0072311 glomerular epithelial cell differentiation; GO:0009987 cellular process; GO:0060041 retina development in camera-type eye; GO:0072009 nephron epithelium development; GO:0001822 kidney development; GO:0003008 system process; GO:0006950 response to stress; GO:0048731 system development; GO:0072210 metanephric nephron development; GO:0072249 metanephric glomerular visceral epithelial cell development; GO:0060560 developmental growth involved in morphogenesis; GO:0050953 sensory perception of light stimulus; GO:0072248 metanephric glomerular visceral epithelial cell differentiation; GO:0031175 neuron projection development; GO:0050808 synapse organization; GO:0072224 metanephric glomerulus development; GO:0010001 glial cell differentiation; GO:0061005 cell differentiation involved in kidney development; GO:0061564 axon development; GO:0030182 neuron differentiation; GO:0048678 response to axon injury; GO:0072243 metanephric nephron epithelium development; GO:0097485 neuron projection guidance; GO:0048588 developmental cell growth; GO:0044767 single-organism developmental process; GO:0006928 movement of cell or subcellular component; GO:0072073 kidney epithelium development; GO:0035850 epithelial cell differentiation involved in kidney development; GO:0048589 developmental growth; GO:0031099 regeneration; GO:0007423 sensory organ development; GO:0040007 growth; GO:0071840 cellular component organization or biogenesis; ","GO:0043260 laminin-11 complex; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0044420 extracellular matrix component; GO:0005576 extracellular region; GO:0043083 synaptic cleft; GO:0045202 synapse; GO:0043256 laminin complex; GO:0005604 basement membrane; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0005605 basal lamina; GO:0031012 extracellular matrix; GO:1903561 extracellular vesicle; GO:0005578 proteinaceous extracellular matrix; GO:0043227 membrane-bounded organelle; GO:0043234 protein complex; GO:0005608 laminin-3 complex; GO:0043230 extracellular organelle; GO:0044456 synapse part; ","GO:0050839 cell adhesion molecule binding; GO:0005102 receptor binding; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0005515 protein binding; GO:0005178 integrin binding; GO:0005198 structural molecule activity; GO:0032403 protein complex binding; ","K06243","LAMB2; laminin, beta 2","hsa05200 Pathways in cancer - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa05146 Amoebiasis - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa05222 Small cell lung cancer - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa04512 ECM-receptor interaction - Homo sapiens (human); hsa05145 Toxoplasmosis - Homo sapiens (human); ","IPR013015; IPR002049; IPR000742; IPR008211; ","\"Laminin IV type B; Laminin EGF domain; EGF-like domain; Laminin, N-terminal; \"\r"]
["P55290","Cadherin-13 OS=Homo sapiens OX=9606 GN=CDH13","CDH13",78.286,32.307,12.8,8,10,8,0.994,1.05,0.984,1.013,0.958,1.029,0.991,0.768,"endoplasmic reticulum\r","GO:0060627 regulation of vesicle-mediated transport; GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0050850 positive regulation of calcium-mediated signaling; GO:0090130 tissue migration; GO:0030335 positive regulation of cell migration; GO:0009891 positive regulation of biosynthetic process; GO:0008285 negative regulation of cell proliferation; GO:0055098 response to low-density lipoprotein particle; GO:0022610 biological adhesion; GO:0001525 angiogenesis; GO:0043542 endothelial cell migration; GO:0050678 regulation of epithelial cell proliferation; GO:0032879 regulation of localization; GO:0009719 response to endogenous stimulus; GO:0007155 cell adhesion; GO:0034332 adherens junction organization; GO:0055094 response to lipoprotein particle; GO:0050921 positive regulation of chemotaxis; GO:0030032 lamellipodium assembly; GO:0001954 positive regulation of cell-matrix adhesion; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044763 single-organism cellular process; GO:0007264 small GTPase mediated signal transduction; GO:0048870 cell motility; GO:0051272 positive regulation of cellular component movement; GO:0031323 regulation of cellular metabolic process; GO:0001938 positive regulation of endothelial cell proliferation; GO:0032501 multicellular organismal process; GO:0010811 positive regulation of cell-substrate adhesion; GO:0050673 epithelial cell proliferation; GO:1903506 regulation of nucleic acid-templated transcription; GO:0010631 epithelial cell migration; GO:0048583 regulation of response to stimulus; GO:0016601 Rac protein signal transduction; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0072359 circulatory system development; GO:0050794 regulation of cellular process; GO:0001952 regulation of cell-matrix adhesion; GO:0044707 single-multicellular organism process; GO:0007162 negative regulation of cell adhesion; GO:0042127 regulation of cell proliferation; GO:0050926 regulation of positive chemotaxis; GO:2000147 positive regulation of cell motility; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0090132 epithelium migration; GO:0009653 anatomical structure morphogenesis; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:2000145 regulation of cell motility; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0001936 regulation of endothelial cell proliferation; GO:0007275 multicellular organism development; GO:0050848 regulation of calcium-mediated signaling; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0009966 regulation of signal transduction; GO:0051254 positive regulation of RNA metabolic process; GO:0030100 regulation of endocytosis; GO:1902531 regulation of intracellular signal transduction; GO:0045785 positive regulation of cell adhesion; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0050927 positive regulation of positive chemotaxis; GO:0032101 regulation of response to external stimulus; GO:0072358 cardiovascular system development; GO:0030334 regulation of cell migration; GO:0008283 cell proliferation; GO:0010033 response to organic substance; GO:0030031 cell projection assembly; GO:0030155 regulation of cell adhesion; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0055096 low-density lipoprotein particle mediated signaling; GO:0031325 positive regulation of cellular metabolic process; GO:0006928 movement of cell or subcellular component; GO:0048661 positive regulation of smooth muscle cell proliferation; GO:0010810 regulation of cell-substrate adhesion; GO:0031328 positive regulation of cellular biosynthetic process; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0008284 positive regulation of cell proliferation; GO:0097581 lamellipodium organization; GO:0043616 keratinocyte proliferation; GO:0051674 localization of cell; GO:0001568 blood vessel development; GO:0040017 positive regulation of locomotion; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0045216 cell-cell junction organization; GO:0044699 single-organism process; GO:0051668 localization within membrane; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0022607 cellular component assembly; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0032103 positive regulation of response to external stimulus; GO:0007266 Rho protein signal transduction; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules; GO:0048514 blood vessel morphogenesis; GO:0070887 cellular response to chemical stimulus; GO:0002040 sprouting angiogenesis; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0071402 cellular response to lipoprotein particle stimulus; GO:0031326 regulation of cellular biosynthetic process; GO:0098609 cell-cell adhesion; GO:0048522 positive regulation of cellular process; GO:0001944 vasculature development; GO:0023052 signaling; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; GO:0030030 cell projection organization; GO:0001667 ameboidal-type cell migration; GO:0019222 regulation of metabolic process; GO:0040011 locomotion; GO:0048856 anatomical structure development; GO:0007265 Ras protein signal transduction; GO:0016043 cellular component organization; GO:0016477 cell migration; GO:0048660 regulation of smooth muscle cell proliferation; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0050896 response to stimulus; GO:1901184 regulation of ERBB signaling pathway; GO:0023056 positive regulation of signaling; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:0071404 cellular response to low-density lipoprotein particle stimulus; GO:0006355 regulation of transcription, DNA-templated; GO:0035556 intracellular signal transduction; GO:0051049 regulation of transport; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0050920 regulation of chemotaxis; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0051641 cellular localization; GO:0034330 cell junction organization; GO:0071495 cellular response to endogenous stimulus; GO:0044767 single-organism developmental process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0042058 regulation of epidermal growth factor receptor signaling pathway; GO:0051128 regulation of cellular component organization; GO:0009967 positive regulation of signal transduction; GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules; GO:0040012 regulation of locomotion; GO:0055095 lipoprotein particle mediated signaling; GO:0007049 cell cycle; GO:0050679 positive regulation of epithelial cell proliferation; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0009897 external side of plasma membrane; GO:0098857 membrane microdomain; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0070062 extracellular exosome; GO:0098590 plasma membrane region; GO:0005925 focal adhesion; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0098805 whole membrane; GO:0098589 membrane region; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0048471 perinuclear region of cytoplasm; GO:0030055 cell-substrate junction; GO:0045121 membrane raft; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0005924 cell-substrate adherens junction; GO:0098552 side of membrane; GO:0042995 cell projection; GO:0031225 anchored component of membrane; GO:0070161 anchoring junction; GO:0005901 caveola; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0044853 plasma membrane raft; GO:0009986 cell surface; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0042562 hormone binding; GO:0043167 ion binding; GO:0046983 protein dimerization activity; GO:0044877 macromolecular complex binding; GO:0005515 protein binding; GO:0071813 lipoprotein particle binding; GO:0050839 cell adhesion molecule binding; GO:0030169 low-density lipoprotein particle binding; GO:0042802 identical protein binding; GO:0005488 binding; GO:0042803 protein homodimerization activity; GO:0045296 cadherin binding; GO:0055100 adiponectin binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005509 calcium ion binding; GO:0071814 protein-lipid complex binding; ","K06808",null,null,"IPR015919; IPR014868; IPR002126; ","Cadherin-like; Cadherin prodomain; Cadherin; \r"]
["P55769","NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13","SNU13",14.173,28.075,27.3,3,5,3,0.937,1.003,1.021,0.974,1.021,1.047,1.027,0.464,"cytoplasm\r","GO:0000003 reproduction; GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0006725 cellular aromatic compound metabolic process; GO:0022414 reproductive process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0042273 ribosomal large subunit biogenesis; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0008152 metabolic process; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0006364 rRNA processing; GO:0000375 RNA splicing, via transesterification reactions; GO:0044702 single organism reproductive process; GO:0000470 maturation of LSU-rRNA; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0016072 rRNA metabolic process; GO:0034470 ncRNA processing; GO:0006396 RNA processing; GO:0042274 ribosomal small subunit biogenesis; GO:0019953 sexual reproduction; GO:0042254 ribosome biogenesis; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0007338 single fertilization; GO:0044238 primary metabolic process; GO:0051704 multi-organism process; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:0009566 fertilization; GO:0090304 nucleic acid metabolic process; GO:0044703 multi-organism reproductive process; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0034660 ncRNA metabolic process; GO:0016071 mRNA metabolic process; GO:0030490 maturation of SSU-rRNA; GO:0071840 cellular component organization or biogenesis; ","GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0071011 precatalytic spliceosome; GO:0044422 organelle part; GO:0030684 preribosome; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0097526 spliceosomal tri-snRNP complex; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0032040 small-subunit processome; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0046540 U4/U6 x U5 tri-snRNP complex; GO:0031981 nuclear lumen; GO:0044452 nucleolar part; GO:0005730 nucleolus; GO:0005681 spliceosomal complex; GO:0097525 spliceosomal snRNP complex; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005732 small nucleolar ribonucleoprotein complex; GO:0031428 box C/D snoRNP complex; GO:0001651 dense fibrillar component; GO:1990904 ribonucleoprotein complex; GO:0043234 protein complex; GO:0030532 small nuclear ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0044428 nuclear part; ","GO:0030515 snoRNA binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0034511 U3 snoRNA binding; GO:0003723 RNA binding; GO:0030622 U4atac snRNA binding; GO:0051117 ATPase binding; GO:0005488 binding; GO:0030621 U4 snRNA binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0034512 box C/D snoRNA binding; GO:0017069 snRNA binding; GO:0019899 enzyme binding; ","K12845","SNU13; U4/U6 small nuclear ribonucleoprotein SNU13","hsa03040 Spliceosome - Homo sapiens (human); hsa03008 Ribosome biogenesis in eukaryotes - Homo sapiens (human); ","IPR029064; IPR004038; ","50S ribosomal protein L30e-like; Ribosomal protein L7Ae/L30e/S12e/Gadd45; \r"]
["P55786","Puromycin-sensitive aminopeptidase OS=Homo sapiens OX=9606 GN=NPEPPS","NPEPPS",103.28,147.68,32.1,27,37,27,0.997,0.99,0.969,1.001,1.02,1.043,1.037,0.0708,"mitochondria\r","GO:0006518 peptide metabolic process; GO:1903955 positive regulation of protein targeting to mitochondrion; GO:1903533 regulation of protein targeting; GO:0044237 cellular metabolic process; GO:0010821 regulation of mitochondrion organization; GO:1903749 positive regulation of establishment of protein localization to mitochondrion; GO:0051130 positive regulation of cellular component organization; GO:0008152 metabolic process; GO:0043171 peptide catabolic process; GO:0032879 regulation of localization; GO:1903747 regulation of establishment of protein localization to mitochondrion; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0070887 cellular response to chemical stimulus; GO:0051716 cellular response to stimulus; GO:0048522 positive regulation of cellular process; GO:0032386 regulation of intracellular transport; GO:0043603 cellular amide metabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0051050 positive regulation of transport; GO:1901575 organic substance catabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0010638 positive regulation of organelle organization; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0051223 regulation of protein transport; GO:0036211 protein modification process; GO:0051222 positive regulation of protein transport; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0090316 positive regulation of intracellular protein transport; GO:0009628 response to abiotic stimulus; GO:1903829 positive regulation of cellular protein localization; GO:0044267 cellular protein metabolic process; GO:0050896 response to stimulus; GO:0070201 regulation of establishment of protein localization; GO:0060341 regulation of cellular localization; GO:0000209 protein polyubiquitination; GO:0071704 organic substance metabolic process; GO:0001666 response to hypoxia; GO:0070482 response to oxygen levels; GO:0044248 cellular catabolic process; GO:0006508 proteolysis; GO:0034641 cellular nitrogen compound metabolic process; GO:0032880 regulation of protein localization; GO:0071453 cellular response to oxygen levels; GO:0009987 cellular process; GO:0033157 regulation of intracellular protein transport; GO:0071456 cellular response to hypoxia; GO:0006950 response to stress; GO:0016567 protein ubiquitination; GO:0032388 positive regulation of intracellular transport; GO:0051049 regulation of transport; GO:0006807 nitrogen compound metabolic process; GO:0033043 regulation of organelle organization; GO:1903214 regulation of protein targeting to mitochondrion; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0010822 positive regulation of mitochondrion organization; GO:1901565 organonitrogen compound catabolic process; GO:1904951 positive regulation of establishment of protein localization; GO:0032446 protein modification by small protein conjugation; GO:0036293 response to decreased oxygen levels; GO:0051128 regulation of cellular component organization; GO:0043412 macromolecule modification; GO:0009056 catabolic process; GO:0036294 cellular response to decreased oxygen levels; GO:1903827 regulation of cellular protein localization; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0008238 exopeptidase activity; GO:0008233 peptidase activity; GO:0043167 ion binding; GO:0070006 metalloaminopeptidase activity; GO:0008235 metalloexopeptidase activity; GO:0004177 aminopeptidase activity; GO:0016787 hydrolase activity; GO:0008237 metallopeptidase activity; GO:0033218 amide binding; GO:0008270 zinc ion binding; GO:0046914 transition metal ion binding; GO:0042277 peptide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0046872 metal ion binding; GO:0043169 cation binding; ","K08776",null,null,"IPR014782; IPR024571; ","\"Peptidase M1, membrane alanine aminopeptidase, N-terminal; ERAP1-like C-terminal domain; \"\r"]
["P55884","Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B","EIF3B",92.48,112.61,27.4,18,32,18,0.966,0.924,0.923,1.077,1.051,1.049,1.129,0.00212,"nucleus\r","GO:0050794 regulation of cellular process; GO:0075522 IRES-dependent viral translational initiation; GO:0075525 viral translational termination-reinitiation; GO:0006518 peptide metabolic process; GO:0019081 viral translation; GO:0060255 regulation of macromolecule metabolic process; GO:0010608 posttranscriptional regulation of gene expression; GO:0019058 viral life cycle; GO:0044267 cellular protein metabolic process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0002181 cytoplasmic translation; GO:0009889 regulation of biosynthetic process; GO:0016032 viral process; GO:0006413 translational initiation; GO:0019080 viral gene expression; GO:0002190 cap-independent translational initiation; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006412 translation; GO:0009059 macromolecule biosynthetic process; GO:0044419 interspecies interaction between organisms; GO:0009987 cellular process; GO:0002183 cytoplasmic translational initiation; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0002192 IRES-dependent translational initiation; GO:0043043 peptide biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0043603 cellular amide metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0051704 multi-organism process; GO:0034248 regulation of cellular amide metabolic process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0051246 regulation of protein metabolic process; GO:0006417 regulation of translation; GO:0044260 cellular macromolecule metabolic process; GO:0006446 regulation of translational initiation; GO:0019222 regulation of metabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0065007 biological regulation; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0005852 eukaryotic translation initiation factor 3 complex; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032947 protein complex scaffold; GO:0008135 translation factor activity, RNA binding; GO:0003723 RNA binding; GO:1901265 nucleoside phosphate binding; GO:0031369 translation initiation factor binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0003743 translation initiation factor activity; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0005198 structural molecule activity; GO:0036094 small molecule binding; ","K03253","EIF3B; translation initiation factor 3 subunit B","hsa03013 RNA transport - Homo sapiens (human); ","IPR000504; IPR013979; IPR012677; IPR015943; IPR034363; ","\"RNA recognition motif domain; Translation initiation factor, beta propellor-like domain; Nucleotide-binding alpha-beta plait domain; WD40/YVTN repeat-like-containing domain; eIF3B, RNA recognition motif; \"\r"]
["P55899","IgG receptor FcRn large subunit p51 OS=Homo sapiens OX=9606 GN=FCGRT","FCGRT",39.743,11.447,17.8,4,7,4,1.077,1.16,1.136,0.881,0.852,0.906,0.782,0.000982,"extracellular\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0051716 cellular response to stimulus; GO:0007166 cell surface receptor signaling pathway; GO:0038094 Fc-gamma receptor signaling pathway; GO:0016192 vesicle-mediated transport; GO:0002414 immunoglobulin transcytosis in epithelial cells; GO:0044699 single-organism process; GO:0002376 immune system process; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0050896 response to stimulus; GO:0050776 regulation of immune response; GO:0051234 establishment of localization; GO:0006810 transport; GO:0019882 antigen processing and presentation; GO:0007165 signal transduction; GO:0050789 regulation of biological process; GO:0007154 cell communication; GO:1902578 single-organism localization; GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor; GO:0048583 regulation of response to stimulus; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0002682 regulation of immune system process; GO:0038093 Fc receptor signaling pathway; GO:0051179 localization; GO:0009987 cellular process; GO:0065007 biological regulation; GO:0045056 transcytosis; GO:0044765 single-organism transport; ","GO:0016020 membrane; GO:0044464 cell part; GO:0071944 cell periphery; GO:0044425 membrane part; GO:0031224 intrinsic component of membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; ","GO:0038023 signaling receptor activity; GO:0019770 IgG receptor activity; GO:0019865 immunoglobulin binding; GO:0044877 macromolecular complex binding; GO:0019763 immunoglobulin receptor activity; GO:0005515 protein binding; GO:0004888 transmembrane signaling receptor activity; GO:0004871 signal transducer activity; GO:0003823 antigen binding; GO:0030881 beta-2-microglobulin binding; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0005488 binding; GO:0019864 IgG binding; GO:0099600 transmembrane receptor activity; GO:0032403 protein complex binding; ",{"$nulls":3},"IPR007110; IPR013783; IPR011161; IPR011162; IPR003597; ","Immunoglobulin-like domain; Immunoglobulin-like fold; MHC class I-like antigen recognition-like; MHC classes I/II-like antigen recognition protein; Immunoglobulin C1-set; \r"]
["P56134","ATP synthase subunit f, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5J2","ATP5J2",10.918,13.44,25.5,2,4,2,0.871,0.953,0.939,1.072,1.058,1.111,1.173,0.00702,"cytoplasm\r","GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0006839 mitochondrial transport; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0009163 nucleoside biosynthetic process; GO:0046129 purine ribonucleoside biosynthetic process; GO:0009156 ribonucleoside monophosphate biosynthetic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0046390 ribose phosphate biosynthetic process; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:1901137 carbohydrate derivative biosynthetic process; GO:0006753 nucleoside phosphate metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0009145 purine nucleoside triphosphate biosynthetic process; GO:0044765 single-organism transport; GO:0018130 heterocycle biosynthetic process; GO:0009206 purine ribonucleoside triphosphate biosynthetic process; GO:0098655 cation transmembrane transport; GO:0044281 small molecule metabolic process; GO:0006754 ATP biosynthetic process; GO:0044763 single-organism cellular process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0015985 energy coupled proton transport, down electrochemical gradient; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0009168 purine ribonucleoside monophosphate biosynthetic process; GO:1902582 single-organism intracellular transport; GO:0042451 purine nucleoside biosynthetic process; GO:0090407 organophosphate biosynthetic process; GO:0006810 transport; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0072522 purine-containing compound biosynthetic process; GO:0044710 single-organism metabolic process; GO:0015986 ATP synthesis coupled proton transport; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0006164 purine nucleotide biosynthetic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0098662 inorganic cation transmembrane transport; GO:0009201 ribonucleoside triphosphate biosynthetic process; GO:0046907 intracellular transport; GO:0009165 nucleotide biosynthetic process; GO:0034220 ion transmembrane transport; GO:0042776 mitochondrial ATP synthesis coupled proton transport; GO:0006725 cellular aromatic compound metabolic process; GO:0009259 ribonucleotide metabolic process; GO:0009142 nucleoside triphosphate biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006812 cation transport; GO:0006139 nucleobase-containing compound metabolic process; GO:1990542 mitochondrial transmembrane transport; GO:1902600 hydrogen ion transmembrane transport; GO:1901135 carbohydrate derivative metabolic process; GO:1902580 single-organism cellular localization; GO:0034641 cellular nitrogen compound metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009119 ribonucleoside metabolic process; GO:0009987 cellular process; GO:0046034 ATP metabolic process; GO:0009124 nucleoside monophosphate biosynthetic process; GO:0044711 single-organism biosynthetic process; GO:0098660 inorganic ion transmembrane transport; GO:0009127 purine nucleoside monophosphate biosynthetic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0042455 ribonucleoside biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0006818 hydrogen transport; GO:0015992 proton transport; GO:0006163 purine nucleotide metabolic process; GO:0051641 cellular localization; GO:0055085 transmembrane transport; GO:0046128 purine ribonucleoside metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0009152 purine ribonucleotide biosynthetic process; GO:0006793 phosphorus metabolic process; GO:1901659 glycosyl compound biosynthetic process; GO:0006811 ion transport; GO:0009260 ribonucleotide biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0051179 localization; GO:0015672 monovalent inorganic cation transport; GO:1901564 organonitrogen compound metabolic process; GO:0009123 nucleoside monophosphate metabolic process; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0032991 macromolecular complex; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044455 mitochondrial membrane part; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0005740 mitochondrial envelope; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain; GO:0005743 mitochondrial inner membrane; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0031981 nuclear lumen; GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o); GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0045259 proton-transporting ATP synthase complex; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005753 mitochondrial proton-transporting ATP synthase complex; GO:0016469 proton-transporting two-sector ATPase complex; GO:0031975 envelope; GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o); GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0022857 transmembrane transporter activity; GO:0005215 transporter activity; ","K02130","ATPeF0F; F-type H+-transporting ATPase subunit f","hsa04714 Thermogenesis - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); "]
["P56199","Integrin alpha-1 OS=Homo sapiens OX=9606 GN=ITGA1","ITGA1",130.85,26.862,8.4,11,14,11,1.1,1.106,1.117,0.901,0.913,0.879,0.81,6.1e-05,"plasma membrane\r","GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0007166 cell surface receptor signaling pathway; GO:1901185 negative regulation of ERBB signaling pathway; GO:0043523 regulation of neuron apoptotic process; GO:0032989 cellular component morphogenesis; GO:0008285 negative regulation of cell proliferation; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0022610 biological adhesion; GO:0009605 response to external stimulus; GO:0044093 positive regulation of molecular function; GO:0007160 cell-matrix adhesion; GO:0007155 cell adhesion; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0051347 positive regulation of transferase activity; GO:0007399 nervous system development; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0048812 neuron projection morphogenesis; GO:0048870 cell motility; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0006935 chemotaxis; GO:0035296 regulation of tube diameter; GO:0000902 cell morphogenesis; GO:0043525 positive regulation of neuron apoptotic process; GO:0050900 leukocyte migration; GO:0032516 positive regulation of phosphoprotein phosphatase activity; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0035304 regulation of protein dephosphorylation; GO:0048583 regulation of response to stimulus; GO:0010604 positive regulation of macromolecule metabolic process; GO:0042330 taxis; GO:0003013 circulatory system process; GO:0043068 positive regulation of programmed cell death; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0042127 regulation of cell proliferation; GO:0050880 regulation of blood vessel size; GO:0031399 regulation of protein modification process; GO:0043067 regulation of programmed cell death; GO:0003018 vascular process in circulatory system; GO:0071902 positive regulation of protein serine/threonine kinase activity; GO:0060326 cell chemotaxis; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0010922 positive regulation of phosphatase activity; GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway; GO:0009653 anatomical structure morphogenesis; GO:0097530 granulocyte migration; GO:0023057 negative regulation of signaling; GO:0032147 activation of protein kinase activity; GO:0010648 negative regulation of cell communication; GO:0051345 positive regulation of hydrolase activity; GO:0043062 extracellular structure organization; GO:0051338 regulation of transferase activity; GO:0007275 multicellular organism development; GO:0035150 regulation of tube size; GO:0009966 regulation of signal transduction; GO:1902531 regulation of intracellular signal transduction; GO:0048731 system development; GO:0002376 immune system process; GO:0030182 neuron differentiation; GO:0051247 positive regulation of protein metabolic process; GO:0043406 positive regulation of MAP kinase activity; GO:0045123 cellular extravasation; GO:0031325 positive regulation of cellular metabolic process; GO:0006928 movement of cell or subcellular component; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0003012 muscle system process; GO:0051674 localization of cell; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:1990266 neutrophil migration; GO:0097746 regulation of blood vessel diameter; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0071621 granulocyte chemotaxis; GO:0007154 cell communication; GO:0097529 myeloid leukocyte migration; GO:0032990 cell part morphogenesis; GO:0009893 positive regulation of metabolic process; GO:0035303 regulation of dephosphorylation; GO:0048858 cell projection morphogenesis; GO:0030198 extracellular matrix organization; GO:0033674 positive regulation of kinase activity; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0045937 positive regulation of phosphate metabolic process; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0007229 integrin-mediated signaling pathway; GO:0010942 positive regulation of cell death; GO:0030593 neutrophil chemotaxis; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0035306 positive regulation of dephosphorylation; GO:0030030 cell projection organization; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0040011 locomotion; GO:0048856 anatomical structure development; GO:0043549 regulation of kinase activity; GO:0045859 regulation of protein kinase activity; GO:0016043 cellular component organization; GO:0016477 cell migration; GO:0043666 regulation of phosphoprotein phosphatase activity; GO:0043405 regulation of MAP kinase activity; GO:0060255 regulation of macromolecule metabolic process; GO:0043065 positive regulation of apoptotic process; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0030154 cell differentiation; GO:0006936 muscle contraction; GO:1901184 regulation of ERBB signaling pathway; GO:1901216 positive regulation of neuron death; GO:0043408 regulation of MAPK cascade; GO:0023056 positive regulation of signaling; GO:0008015 blood circulation; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:1901214 regulation of neuron death; GO:0003008 system process; GO:0097755 positive regulation of blood vessel diameter; GO:0035307 positive regulation of protein dephosphorylation; GO:0010921 regulation of phosphatase activity; GO:0001932 regulation of protein phosphorylation; GO:0031401 positive regulation of protein modification process; GO:0048585 negative regulation of response to stimulus; GO:0045860 positive regulation of protein kinase activity; GO:0031175 neuron projection development; GO:0001934 positive regulation of protein phosphorylation; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0042311 vasodilation; GO:0000187 activation of MAPK activity; GO:0030595 leukocyte chemotaxis; GO:0031589 cell-substrate adhesion; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0090066 regulation of anatomical structure size; GO:0009967 positive regulation of signal transduction; GO:0042058 regulation of epidermal growth factor receptor signaling pathway; GO:0043410 positive regulation of MAPK cascade; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0098636 protein complex involved in cell adhesion; GO:0009897 external side of plasma membrane; GO:0031410 cytoplasmic vesicle; GO:0098857 membrane microdomain; GO:0030054 cell junction; GO:0098796 membrane protein complex; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0043025 neuronal cell body; GO:0032991 macromolecular complex; GO:0034665 integrin alpha1-beta1 complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0099503 secretory vesicle; GO:0098805 whole membrane; GO:0098589 membrane region; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0030141 secretory granule; GO:0030055 cell-substrate junction; GO:0045121 membrane raft; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0005924 cell-substrate adherens junction; GO:0098552 side of membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0031226 intrinsic component of plasma membrane; GO:0098802 plasma membrane receptor complex; GO:0098797 plasma membrane protein complex; GO:0070161 anchoring junction; GO:0043235 receptor complex; GO:0012505 endomembrane system; GO:0008305 integrin complex; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0044459 plasma membrane part; GO:0001669 acrosomal vesicle; GO:0043204 perikaryon; GO:0044297 cell body; GO:0009986 cell surface; GO:0097223 sperm part; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0045178 basal part of cell; ","GO:0098639 collagen binding involved in cell-matrix adhesion; GO:0019903 protein phosphatase binding; GO:0005102 receptor binding; GO:0043167 ion binding; GO:0044877 macromolecular complex binding; GO:0005515 protein binding; GO:0098631 protein binding involved in cell adhesion; GO:0005488 binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005518 collagen binding; GO:0019902 phosphatase binding; GO:0019899 enzyme binding; GO:0098634 protein binding involved in cell-matrix adhesion; GO:0032403 protein complex binding; ","K06480","ITGA1; integrin alpha 1","hsa05414 Dilated cardiomyopathy (DCM) - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa04640 Hematopoietic cell lineage - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa04512 ECM-receptor interaction - Homo sapiens (human); hsa05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human); hsa05410 Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human); ","IPR032695; IPR013649; IPR002035; ","\"Integrin domain; Integrin alpha-2; von Willebrand factor, type A; \"\r"]
["P56537","Eukaryotic translation initiation factor 6 OS=Homo sapiens OX=9606 GN=EIF6","EIF6",26.599,54.002,33.1,6,10,6,0.877,0.84,0.791,1.198,1.061,1.16,1.363,0.00276,"cyto_nucl\r","GO:0050658 RNA transport; GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0006518 peptide metabolic process; GO:0032270 positive regulation of cellular protein metabolic process; GO:0022618 ribonucleoprotein complex assembly; GO:0010608 posttranscriptional regulation of gene expression; GO:0009891 positive regulation of biosynthetic process; GO:0051169 nuclear transport; GO:0000460 maturation of 5.8S rRNA; GO:0071428 rRNA-containing ribonucleoprotein complex export from nucleus; GO:0019216 regulation of lipid metabolic process; GO:0044237 cellular metabolic process; GO:0042273 ribosomal large subunit biogenesis; GO:0015031 protein transport; GO:0008152 metabolic process; GO:0015931 nucleobase-containing compound transport; GO:0065003 macromolecular complex assembly; GO:0006364 rRNA processing; GO:0000470 maturation of LSU-rRNA; GO:0009719 response to endogenous stimulus; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0008104 protein localization; GO:1901652 response to peptide; GO:0006396 RNA processing; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0034249 negative regulation of cellular amide metabolic process; GO:0042254 ribosome biogenesis; GO:0031323 regulation of cellular metabolic process; GO:0006611 protein export from nucleus; GO:0042256 mature ribosome assembly; GO:0006810 transport; GO:0010243 response to organonitrogen compound; GO:0031047 gene silencing by RNA; GO:0032269 negative regulation of cellular protein metabolic process; GO:0045652 regulation of megakaryocyte differentiation; GO:0046890 regulation of lipid biosynthetic process; GO:1901698 response to nitrogen compound; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0042304 regulation of fatty acid biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0002682 regulation of immune system process; GO:0006913 nucleocytoplasmic transport; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0035278 miRNA mediated inhibition of translation; GO:0006140 regulation of nucleotide metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0051640 organelle localization; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0045974 regulation of translation, ncRNA-mediated; GO:0033750 ribosome localization; GO:0044267 cellular protein metabolic process; GO:1901700 response to oxygen-containing compound; GO:0017148 negative regulation of translation; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0051239 regulation of multicellular organismal process; GO:0051236 establishment of RNA localization; GO:1903706 regulation of hemopoiesis; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034613 cellular protein localization; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0006403 RNA localization; GO:0006405 RNA export from nucleus; GO:0071702 organic substance transport; GO:0010033 response to organic substance; GO:0051656 establishment of organelle localization; GO:0006109 regulation of carbohydrate metabolic process; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0042255 ribosome assembly; GO:0034248 regulation of cellular amide metabolic process; GO:0019217 regulation of fatty acid metabolic process; GO:0045184 establishment of protein localization; GO:0009890 negative regulation of biosynthetic process; GO:0051247 positive regulation of protein metabolic process; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0051179 localization; GO:0031328 positive regulation of cellular biosynthetic process; GO:0035195 gene silencing by miRNA; GO:0050793 regulation of developmental process; GO:1901564 organonitrogen compound metabolic process; GO:0043467 regulation of generation of precursor metabolites and energy; GO:0040033 negative regulation of translation, ncRNA-mediated; GO:0045637 regulation of myeloid cell differentiation; GO:0035194 posttranscriptional gene silencing by RNA; GO:0033753 establishment of ribosome localization; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0051168 nuclear export; GO:0051234 establishment of localization; GO:0051196 regulation of coenzyme metabolic process; GO:0051649 establishment of localization in cell; GO:0071826 ribonucleoprotein complex subunit organization; GO:0009893 positive regulation of metabolic process; GO:0022607 cellular component assembly; GO:0050657 nucleic acid transport; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0006413 translational initiation; GO:0006412 translation; GO:0033036 macromolecule localization; GO:0051193 regulation of cofactor metabolic process; GO:0034470 ncRNA processing; GO:0016072 rRNA metabolic process; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0045727 positive regulation of translation; GO:0043043 peptide biosynthetic process; GO:0006110 regulation of glycolytic process; GO:0043470 regulation of carbohydrate catabolic process; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0071166 ribonucleoprotein complex localization; GO:0010565 regulation of cellular ketone metabolic process; GO:0016070 RNA metabolic process; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0000054 ribosomal subunit export from nucleus; GO:0042221 response to chemical; GO:0032868 response to insulin; GO:0090304 nucleic acid metabolic process; GO:0043434 response to peptide hormone; GO:0019222 regulation of metabolic process; GO:1902626 assembly of large subunit precursor of preribosome; GO:0019220 regulation of phosphate metabolic process; GO:2000377 regulation of reactive oxygen species metabolic process; GO:2000026 regulation of multicellular organismal development; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0009118 regulation of nucleoside metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0070925 organelle assembly; GO:0006886 intracellular protein transport; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:1903578 regulation of ATP metabolic process; GO:0034622 cellular macromolecular complex assembly; GO:0010629 negative regulation of gene expression; GO:0016441 posttranscriptional gene silencing; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0051641 cellular localization; GO:1900542 regulation of purine nucleotide metabolic process; GO:0040029 regulation of gene expression, epigenetic; GO:0016458 gene silencing; GO:0070727 cellular macromolecule localization; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0071426 ribonucleoprotein complex export from nucleus; GO:0051246 regulation of protein metabolic process; GO:0006417 regulation of translation; GO:0051248 negative regulation of protein metabolic process; GO:0034250 positive regulation of cellular amide metabolic process; GO:0010467 gene expression; GO:0031327 negative regulation of cellular biosynthetic process; GO:0043604 amide biosynthetic process; GO:0009725 response to hormone; GO:0034660 ncRNA metabolic process; GO:0071705 nitrogen compound transport; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0030684 preribosome; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0030687 preribosome, large subunit precursor; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0043022 ribosome binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0008135 translation factor activity, RNA binding; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0003676 nucleic acid binding; GO:0003743 translation initiation factor activity; GO:0005515 protein binding; GO:0043023 ribosomal large subunit binding; GO:0043021 ribonucleoprotein complex binding; ","K03264","EIF6; translation initiation factor 6","hsa03008 Ribosome biogenesis in eukaryotes - Homo sapiens (human); "]
["P56589","Peroxisomal biogenesis factor 3 OS=Homo sapiens OX=9606 GN=PEX3","PEX3",42.139,26.96,14.2,4,4,4,0.979,1.036,1.047,0.979,1.018,0.952,0.963,0.258,"peroxisome\r","GO:0044085 cellular component biogenesis; GO:0046907 intracellular transport; GO:0016557 peroxisome membrane biogenesis; GO:0016043 cellular component organization; GO:0072594 establishment of protein localization to organelle; GO:0015919 peroxisomal membrane transport; GO:0017038 protein import; GO:0072663 establishment of protein localization to peroxisome; GO:0044699 single-organism process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0007031 peroxisome organization; GO:0006612 protein targeting to membrane; GO:0051649 establishment of localization in cell; GO:1902578 single-organism localization; GO:0043574 peroxisomal transport; GO:0006886 intracellular protein transport; GO:0065002 intracellular protein transmembrane transport; GO:1902580 single-organism cellular localization; GO:0033365 protein localization to organelle; GO:0034613 cellular protein localization; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0044743 protein transmembrane import into intracellular organelle; GO:0090150 establishment of protein localization to membrane; GO:0009987 cellular process; GO:0044765 single-organism transport; GO:0072662 protein localization to peroxisome; GO:0072657 protein localization to membrane; GO:0071806 protein transmembrane transport; GO:0044763 single-organism cellular process; GO:0071702 organic substance transport; GO:0006625 protein targeting to peroxisome; GO:0044091 membrane biogenesis; GO:1902582 single-organism intracellular transport; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:1902589 single-organism organelle organization; GO:0055085 transmembrane transport; GO:0070727 cellular macromolecule localization; GO:0006996 organelle organization; GO:0045046 protein import into peroxisome membrane; GO:0051179 localization; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044438 microbody part; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005778 peroxisomal membrane; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0031301 integral component of organelle membrane; GO:0070013 intracellular organelle lumen; GO:0032994 protein-lipid complex; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0042579 microbody; GO:0005779 integral component of peroxisomal membrane; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0031903 microbody membrane; GO:0031231 intrinsic component of peroxisomal membrane; GO:0044439 peroxisomal part; GO:0098588 bounding membrane of organelle; GO:0005777 peroxisome; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0016021 integral component of membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0043234 protein complex; GO:0031300 intrinsic component of organelle membrane; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0008289 lipid binding; GO:0005515 protein binding; GO:0005488 binding; GO:0046983 protein dimerization activity; ","K13336","PEX3; peroxin-3","hsa04146 Peroxisome - Homo sapiens (human); "]
["P57730","Caspase recruitment domain-containing protein 18 OS=Homo sapiens OX=9606 GN=CARD18","CARD18",10.138,3.78,22.2,2,2,2,1.027,0.878,0.803,1.091,1.101,1.1,1.216,0.108,"mitochondria\r","GO:0050794 regulation of cellular process; GO:0010941 regulation of cell death; GO:0010951 negative regulation of endopeptidase activity; GO:0060255 regulation of macromolecule metabolic process; GO:0043067 regulation of programmed cell death; GO:0044699 single-organism process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0051346 negative regulation of hydrolase activity; GO:0010466 negative regulation of peptidase activity; GO:0006915 apoptotic process; GO:0009987 cellular process; GO:0052548 regulation of endopeptidase activity; GO:0045861 negative regulation of proteolysis; GO:0006950 response to stress; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0030162 regulation of proteolysis; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0009892 negative regulation of metabolic process; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0051336 regulation of hydrolase activity; GO:0008219 cell death; GO:0050790 regulation of catalytic activity; GO:0051246 regulation of protein metabolic process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0006954 inflammatory response; GO:0065009 regulation of molecular function; GO:0051248 negative regulation of protein metabolic process; GO:0019222 regulation of metabolic process; GO:0097194 execution phase of apoptosis; GO:0044092 negative regulation of molecular function; GO:0012501 programmed cell death; GO:0006952 defense response; GO:0052547 regulation of peptidase activity; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0044424 intracellular part; GO:0005623 cell; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; ","GO:0008233 peptidase activity; GO:0061134 peptidase regulator activity; GO:0016787 hydrolase activity; GO:0008234 cysteine-type peptidase activity; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0004866 endopeptidase inhibitor activity; GO:0004869 cysteine-type endopeptidase inhibitor activity; GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis; GO:0004175 endopeptidase activity; GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process; GO:0030234 enzyme regulator activity; GO:0003824 catalytic activity; GO:0030414 peptidase inhibitor activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0061135 endopeptidase regulator activity; GO:0004197 cysteine-type endopeptidase activity; ","K12806","CARD16_17_18; caspase recruitment domain-containing protein 16/17/18","hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human); ","IPR011029; IPR001315; ","Death-like domain; CARD domain; \r"]
["P57764","Gasdermin-D OS=Homo sapiens OX=9606 GN=GSDMD","GSDMD",52.8,1.9743,1.7,1,1,1,0.997,0.932,1.012,1.048,0.953,1.063,1.042,0.396,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0098542 defense response to other organism; GO:0032651 regulation of interleukin-1 beta production; GO:0051046 regulation of secretion; GO:0044699 single-organism process; GO:0035915 pore formation in membrane of other organism; GO:0044764 multi-organism cellular process; GO:0035821 modification of morphology or physiology of other organism; GO:0051234 establishment of localization; GO:0009607 response to biotic stimulus; GO:0046931 pore complex assembly; GO:0009605 response to external stimulus; GO:0070269 pyroptosis; GO:0032732 positive regulation of interleukin-1 production; GO:0007154 cell communication; GO:0051240 positive regulation of multicellular organismal process; GO:0022607 cellular component assembly; GO:0032879 regulation of localization; GO:0065003 macromolecular complex assembly; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0050829 defense response to Gram-negative bacterium; GO:0071822 protein complex subunit organization; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0050707 regulation of cytokine secretion; GO:1903530 regulation of secretion by cell; GO:0050830 defense response to Gram-positive bacterium; GO:0002444 myeloid leukocyte mediated immunity; GO:0051704 multi-organism process; GO:0051050 positive regulation of transport; GO:0006810 transport; GO:0050789 regulation of biological process; GO:1903532 positive regulation of secretion by cell; GO:0032940 secretion by cell; GO:0006954 inflammatory response; GO:0050714 positive regulation of protein secretion; GO:0051223 regulation of protein transport; GO:0043299 leukocyte degranulation; GO:0006952 defense response; GO:0070271 protein complex biogenesis; GO:0050715 positive regulation of cytokine secretion; GO:0051222 positive regulation of protein transport; GO:0051047 positive regulation of secretion; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0019835 cytolysis; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0051260 protein homooligomerization; GO:0001819 positive regulation of cytokine production; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0045087 innate immune response; GO:0070201 regulation of establishment of protein localization; GO:0051239 regulation of multicellular organismal process; GO:0051259 protein oligomerization; GO:0032731 positive regulation of interleukin-1 beta production; GO:0009991 response to extracellular stimulus; GO:0050718 positive regulation of interleukin-1 beta secretion; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0050716 positive regulation of interleukin-1 secretion; GO:0036230 granulocyte activation; GO:0032880 regulation of protein localization; GO:0050708 regulation of protein secretion; GO:0009987 cellular process; GO:0009617 response to bacterium; GO:0006461 protein complex assembly; GO:0032652 regulation of interleukin-1 production; GO:0006950 response to stress; GO:0042742 defense response to bacterium; GO:0051049 regulation of transport; GO:0016192 vesicle-mediated transport; GO:0051673 membrane disruption in other organism; GO:0071496 cellular response to external stimulus; GO:0002376 immune system process; GO:0043312 neutrophil degranulation; GO:0002263 cell activation involved in immune response; GO:0048518 positive regulation of biological process; GO:0031668 cellular response to extracellular stimulus; GO:0043933 macromolecular complex subunit organization; GO:0002366 leukocyte activation involved in immune response; GO:0050706 regulation of interleukin-1 beta secretion; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:1904951 positive regulation of establishment of protein localization; GO:0008219 cell death; GO:0050704 regulation of interleukin-1 secretion; GO:0001775 cell activation; GO:0001817 regulation of cytokine production; GO:0012501 programmed cell death; GO:0051179 localization; GO:0006955 immune response; GO:0006887 exocytosis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0034774 secretory granule lumen; GO:0016020 membrane; GO:1904724 tertiary granule lumen; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0072559 NLRP3 inflammasome complex; GO:0044424 intracellular part; GO:0061702 inflammasome complex; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0044445 cytosolic part; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0070820 tertiary granule; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0035580 specific granule lumen; GO:0042581 specific granule; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:1901981 phosphatidylinositol phosphate binding; GO:1901612 cardiolipin binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0001786 phosphatidylserine binding; GO:1902936 phosphatidylinositol bisphosphate binding; GO:1901611 phosphatidylglycerol binding; GO:0072341 modified amino acid binding; GO:0070300 phosphatidic acid binding; GO:0005488 binding; GO:0005546 phosphatidylinositol-4,5-bisphosphate binding; GO:0005543 phospholipid binding; GO:0035091 phosphatidylinositol binding; GO:0008289 lipid binding; GO:0043168 anion binding; GO:0070273 phosphatidylinositol-4-phosphate binding; ","K20917","GSDMD; gasdermin-D","hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human); "]
["P58107","Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1","EPPK1",555.65,323.31,38.4,63,99,56,0.934,0.956,0.96,1.053,1.031,1.028,1.092,0.00152,"nucleus\r","GO:0010839 negative regulation of keratinocyte proliferation; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0045109 intermediate filament organization; GO:0040008 regulation of growth; GO:0042127 regulation of cell proliferation; GO:0010837 regulation of keratinocyte proliferation; GO:0010633 negative regulation of epithelial cell migration; GO:0051547 regulation of keratinocyte migration; GO:0051548 negative regulation of keratinocyte migration; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0048638 regulation of developmental growth; GO:0051239 regulation of multicellular organismal process; GO:0008285 negative regulation of cell proliferation; GO:0009611 response to wounding; GO:0040013 negative regulation of locomotion; GO:1905041 regulation of epithelium regeneration; GO:0032879 regulation of localization; GO:2000145 regulation of cell motility; GO:0050678 regulation of epithelial cell proliferation; GO:0032102 negative regulation of response to external stimulus; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0045104 intermediate filament cytoskeleton organization; GO:0006950 response to stress; GO:0010632 regulation of epithelial cell migration; GO:0051270 regulation of cellular component movement; GO:0045103 intermediate filament-based process; GO:0044763 single-organism cellular process; GO:0032101 regulation of response to external stimulus; GO:0030334 regulation of cell migration; GO:0048585 negative regulation of response to stimulus; GO:2000146 negative regulation of cell motility; GO:0061045 negative regulation of wound healing; GO:1903035 negative regulation of response to wounding; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0042060 wound healing; GO:0061041 regulation of wound healing; GO:0030336 negative regulation of cell migration; GO:0006996 organelle organization; GO:0048583 regulation of response to stimulus; GO:0040012 regulation of locomotion; GO:0050680 negative regulation of epithelial cell proliferation; GO:0050793 regulation of developmental process; GO:1903034 regulation of response to wounding; GO:0097435 supramolecular fiber organization; GO:0051271 negative regulation of cellular component movement; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016323 basolateral plasma membrane; GO:0016020 membrane; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0097356 perinucleolar compartment; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0005911 cell-cell junction; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0031974 membrane-enclosed lumen; GO:0016327 apicolateral plasma membrane; GO:0070160 occluding junction; GO:0070013 intracellular organelle lumen; GO:0098590 plasma membrane region; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0030055 cell-substrate junction; GO:0030056 hemidesmosome; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005923 bicellular tight junction; GO:0045095 keratin filament; GO:0043296 apical junction complex; GO:0099081 supramolecular polymer; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0045111 intermediate filament cytoskeleton; GO:0005882 intermediate filament; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0008092 cytoskeletal protein binding; GO:0019215 intermediate filament binding; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0032403 protein complex binding; "]
["P58546","Myotrophin OS=Homo sapiens OX=9606 GN=MTPN","MTPN",12.895,40.992,39,5,10,5,1.023,0.949,0.994,1.033,1.006,0.959,1.011,0.745,"cytoplasm\r","GO:0065008 regulation of biological quality; GO:0007420 brain development; GO:0010608 posttranscriptional regulation of gene expression; GO:0009891 positive regulation of biosynthetic process; GO:0014742 positive regulation of muscle hypertrophy; GO:0030832 regulation of actin filament length; GO:0044237 cellular metabolic process; GO:0045927 positive regulation of growth; GO:0001558 regulation of cell growth; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0014743 regulation of muscle hypertrophy; GO:0051240 positive regulation of multicellular organismal process; GO:0032535 regulation of cellular component size; GO:0044093 positive regulation of molecular function; GO:0044057 regulation of system process; GO:0051493 regulation of cytoskeleton organization; GO:0021587 cerebellum morphogenesis; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0071214 cellular response to abiotic stimulus; GO:0021575 hindbrain morphogenesis; GO:0080090 regulation of primary metabolic process; GO:0030307 positive regulation of cell growth; GO:0048699 generation of neurons; GO:0016049 cell growth; GO:0044763 single-organism cellular process; GO:0009712 catechol-containing compound metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0021549 cerebellum development; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0051092 positive regulation of NF-kappaB transcription factor activity; GO:0007417 central nervous system development; GO:0051090 regulation of sequence-specific DNA binding transcription factor activity; GO:0018958 phenol-containing compound metabolic process; GO:0021707 cerebellar granule cell differentiation; GO:0021696 cerebellar cortex morphogenesis; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0030834 regulation of actin filament depolymerization; GO:0021695 cerebellar cortex development; GO:1902903 regulation of supramolecular fiber organization; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:1901615 organic hydroxy compound metabolic process; GO:0032956 regulation of actin cytoskeleton organization; GO:0009628 response to abiotic stimulus; GO:0021953 central nervous system neuron differentiation; GO:0051239 regulation of multicellular organismal process; GO:0009653 anatomical structure morphogenesis; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0061061 muscle structure development; GO:0007275 multicellular organism development; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0030902 hindbrain development; GO:0006950 response to stress; GO:0048731 system development; GO:1901879 regulation of protein depolymerization; GO:0032970 regulation of actin filament-based process; GO:0021681 cerebellar granular layer development; GO:0071496 cellular response to external stimulus; GO:0010611 regulation of cardiac muscle hypertrophy; GO:0034248 regulation of cellular amide metabolic process; GO:0008064 regulation of actin polymerization or depolymerization; GO:0030182 neuron differentiation; GO:0043502 regulation of muscle adaptation; GO:0051247 positive regulation of protein metabolic process; GO:0010613 positive regulation of cardiac muscle hypertrophy; GO:0048589 developmental growth; GO:0040007 growth; GO:0050793 regulation of developmental process; GO:1901564 organonitrogen compound metabolic process; GO:0030833 regulation of actin filament polymerization; GO:0048869 cellular developmental process; GO:0048634 regulation of muscle organ development; GO:0021684 cerebellar granular layer formation; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0021533 cell differentiation in hindbrain; GO:0009611 response to wounding; GO:2001141 regulation of RNA biosynthetic process; GO:0021697 cerebellar cortex formation; GO:0009893 positive regulation of metabolic process; GO:0032271 regulation of protein polymerization; GO:0060322 head development; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0009888 tissue development; GO:0031326 regulation of cellular biosynthetic process; GO:0042246 tissue regeneration; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity; GO:0090257 regulation of muscle system process; GO:0006584 catecholamine metabolic process; GO:0016202 regulation of striated muscle tissue development; GO:0043254 regulation of protein complex assembly; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0022037 metencephalon development; GO:0043244 regulation of protein complex disassembly; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0016043 cellular component organization; GO:0071260 cellular response to mechanical stimulus; GO:0040008 regulation of growth; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044087 regulation of cellular component biogenesis; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0009612 response to mechanical stimulus; GO:0030154 cell differentiation; GO:0009987 cellular process; GO:2000812 regulation of barbed-end actin filament capping; GO:0051146 striated muscle cell differentiation; GO:0043403 skeletal muscle tissue regeneration; GO:0006355 regulation of transcription, DNA-templated; GO:0021683 cerebellar granular layer morphogenesis; GO:1901861 regulation of muscle tissue development; GO:0033043 regulation of organelle organization; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0042060 wound healing; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0006417 regulation of translation; GO:0090066 regulation of anatomical structure size; GO:0042692 muscle cell differentiation; GO:0051128 regulation of cellular component organization; GO:0031099 regeneration; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005856 cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0008290 F-actin capping protein complex; GO:0005829 cytosol; GO:0015629 actin cytoskeleton; GO:0005576 extracellular region; GO:0043226 organelle; GO:0030424 axon; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003677 DNA binding; GO:0005515 protein binding; GO:0043565 sequence-specific DNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; ",{"$nulls":3},"IPR020683; ","Ankyrin repeat-containing domain; \r"]
["P59768","Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 OS=Homo sapiens OX=9606 GN=GNG2","GNG2",7.8501,16.513,42.3,2,7,2,1.077,1.135,1.073,0.909,0.901,0.969,0.846,0.0046,"extracellular\r","GO:0044700 single organism signaling; GO:0001101 response to acid chemical; GO:0065008 regulation of biological quality; GO:0007596 blood coagulation; GO:0034695 response to prostaglandin E; GO:0007166 cell surface receptor signaling pathway; GO:0044699 single-organism process; GO:0035567 non-canonical Wnt signaling pathway; GO:0009611 response to wounding; GO:0006457 protein folding; GO:0007165 signal transduction; GO:1901653 cellular response to peptide; GO:0007154 cell communication; GO:0009719 response to endogenous stimulus; GO:0016055 Wnt signaling pathway; GO:1901652 response to peptide; GO:0070887 cellular response to chemical stimulus; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0071869 response to catecholamine; GO:0071868 cellular response to monoamine stimulus; GO:0030168 platelet activation; GO:0007212 dopamine receptor signaling pathway; GO:0071398 cellular response to fatty acid; GO:0044763 single-organism cellular process; GO:0007223 Wnt signaling pathway, calcium modulating pathway; GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0071396 cellular response to lipid; GO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway; GO:0198738 cell-cell signaling by wnt; GO:0071417 cellular response to organonitrogen compound; GO:0010243 response to organonitrogen compound; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0007267 cell-cell signaling; GO:0043434 response to peptide hormone; GO:1901699 cellular response to nitrogen compound; GO:0032870 cellular response to hormone stimulus; GO:1901698 response to nitrogen compound; GO:0050817 coagulation; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0071310 cellular response to organic substance; GO:1901700 response to oxygen-containing compound; GO:0071867 response to monoamine; GO:0050896 response to stimulus; GO:0007599 hemostasis; GO:0071377 cellular response to glucagon stimulus; GO:0033993 response to lipid; GO:0071229 cellular response to acid chemical; GO:0071375 cellular response to peptide hormone stimulus; GO:0071380 cellular response to prostaglandin E stimulus; GO:0009987 cellular process; GO:0070542 response to fatty acid; GO:0050878 regulation of body fluid levels; GO:1901655 cellular response to ketone; GO:0006950 response to stress; GO:0034694 response to prostaglandin; GO:0071407 cellular response to organic cyclic compound; GO:0008283 cell proliferation; GO:0010033 response to organic substance; GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway; GO:0007186 G-protein coupled receptor signaling pathway; GO:1901701 cellular response to oxygen-containing compound; GO:0042060 wound healing; GO:0071495 cellular response to endogenous stimulus; GO:0071870 cellular response to catecholamine stimulus; GO:0001775 cell activation; GO:0033762 response to glucagon; GO:0009725 response to hormone; GO:0071379 cellular response to prostaglandin stimulus; GO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; GO:1901654 response to ketone; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:1905360 GTPase complex; GO:0044421 extracellular region part; GO:0019898 extrinsic component of membrane; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0098797 plasma membrane protein complex; GO:0031982 vesicle; GO:0019897 extrinsic component of plasma membrane; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0031234 extrinsic component of cytoplasmic side of plasma membrane; GO:0009898 cytoplasmic side of plasma membrane; GO:0098562 cytoplasmic side of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:1902494 catalytic complex; GO:0044459 plasma membrane part; GO:0005834 heterotrimeric G-protein complex; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0098552 side of membrane; ","GO:0031681 G-protein beta-subunit binding; GO:0005515 protein binding; GO:0004871 signal transducer activity; GO:0005488 binding; ","K07826","GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2","hsa05200 Pathways in cancer - Homo sapiens (human); hsa04728 Dopaminergic synapse - Homo sapiens (human); hsa04371 Apelin signaling pathway - Homo sapiens (human); hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human); hsa04727 GABAergic synapse - Homo sapiens (human); hsa04014 Ras signaling pathway - Homo sapiens (human); hsa05167 Kaposi's sarcoma-associated herpesvirus infection - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa05034 Alcoholism - Homo sapiens (human); hsa04726 Serotonergic synapse - Homo sapiens (human); hsa04713 Circadian entrainment - Homo sapiens (human); hsa04724 Glutamatergic synapse - Homo sapiens (human); hsa04926 Relaxin signaling pathway - Homo sapiens (human); hsa05032 Morphine addiction - Homo sapiens (human); hsa04725 Cholinergic synapse - Homo sapiens (human); hsa04062 Chemokine signaling pathway - Homo sapiens (human); ","IPR015898; ","G-protein gamma-like domain; \r"]
["P60174","Triosephosphate isomerase OS=Homo sapiens OX=9606 GN=TPI1","TPI1",30.791,227.86,66.1,17,57,17,1.031,0.997,1.007,1,0.981,1.004,0.984,0.248,"cytoplasm\r","GO:0046365 monosaccharide catabolic process; GO:0006757 ATP generation from ADP; GO:0006739 NADP metabolic process; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0006165 nucleoside diphosphate phosphorylation; GO:0046031 ADP metabolic process; GO:0019362 pyridine nucleotide metabolic process; GO:0019319 hexose biosynthetic process; GO:0006096 glycolytic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0006066 alcohol metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0009185 ribonucleoside diphosphate metabolic process; GO:0046939 nucleotide phosphorylation; GO:0009135 purine nucleoside diphosphate metabolic process; GO:0072524 pyridine-containing compound metabolic process; GO:0044237 cellular metabolic process; GO:0061615 glycolytic process through fructose-6-phosphate; GO:0006796 phosphate-containing compound metabolic process; GO:0006006 glucose metabolic process; GO:0008152 metabolic process; GO:0006094 gluconeogenesis; GO:1901137 carbohydrate derivative biosynthetic process; GO:0006091 generation of precursor metabolites and energy; GO:0044262 cellular carbohydrate metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0006098 pentose-phosphate shunt; GO:0032787 monocarboxylic acid metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0032502 developmental process; GO:0009179 purine ribonucleoside diphosphate metabolic process; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006081 cellular aldehyde metabolic process; GO:0061620 glycolytic process through glucose-6-phosphate; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0006732 coenzyme metabolic process; GO:0005975 carbohydrate metabolic process; GO:0032501 multicellular organismal process; GO:0061718 glucose catabolic process to pyruvate; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0051186 cofactor metabolic process; GO:0016052 carbohydrate catabolic process; GO:0090407 organophosphate biosynthetic process; GO:0019405 alditol catabolic process; GO:1901575 organic substance catabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0019674 NAD metabolic process; GO:0044710 single-organism metabolic process; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:0043436 oxoacid metabolic process; GO:0044707 single-multicellular organism process; GO:0016310 phosphorylation; GO:0016051 carbohydrate biosynthetic process; GO:1901615 organic hydroxy compound metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0046496 nicotinamide nucleotide metabolic process; GO:0009259 ribonucleotide metabolic process; GO:0044275 cellular carbohydrate catabolic process; GO:0006734 NADH metabolic process; GO:0006071 glycerol metabolic process; GO:0046364 monosaccharide biosynthetic process; GO:0006735 NADH regeneration; GO:0046164 alcohol catabolic process; GO:0071704 organic substance metabolic process; GO:0061621 canonical glycolysis; GO:0051156 glucose 6-phosphate metabolic process; GO:0006090 pyruvate metabolic process; GO:1901616 organic hydroxy compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0019682 glyceraldehyde-3-phosphate metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0005996 monosaccharide metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0046184 aldehyde biosynthetic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009119 ribonucleoside metabolic process; GO:0009987 cellular process; GO:0009132 nucleoside diphosphate metabolic process; GO:0046034 ATP metabolic process; GO:0019400 alditol metabolic process; GO:0019563 glycerol catabolic process; GO:0044724 single-organism carbohydrate catabolic process; GO:0044711 single-organism biosynthetic process; GO:0044712 single-organism catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044282 small molecule catabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0019751 polyol metabolic process; GO:0044249 cellular biosynthetic process; GO:0006163 purine nucleotide metabolic process; GO:0046128 purine ribonucleoside metabolic process; GO:0006007 glucose catabolic process; GO:0046166 glyceraldehyde-3-phosphate biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0044767 single-organism developmental process; GO:0044283 small molecule biosynthetic process; GO:0019752 carboxylic acid metabolic process; GO:0019637 organophosphate metabolic process; GO:0019320 hexose catabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0009056 catabolic process; GO:0046174 polyol catabolic process; GO:0019318 hexose metabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0043229 intracellular organelle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016853 isomerase activity; GO:0004807 triose-phosphate isomerase activity; GO:0031625 ubiquitin protein ligase binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0005515 protein binding; GO:0016860 intramolecular oxidoreductase activity; GO:0044389 ubiquitin-like protein ligase binding; GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses; GO:0019899 enzyme binding; ","K01803","TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]","hsa00051 Fructose and mannose metabolism - Homo sapiens (human); hsa00562 Inositol phosphate metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human); hsa01230 Biosynthesis of amino acids - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); ","IPR013785; ","Aldolase-type TIM barrel; \r"]
["P60468","Protein transport protein Sec61 subunit beta OS=Homo sapiens OX=9606 GN=SEC61B","SEC61B",9.9743,11.793,37.5,3,5,3,0.888,1.031,1.013,1.063,1.072,1.006,1.071,0.239,"mitochondria\r","GO:0044700 single organism signaling; GO:0072594 establishment of protein localization to organelle; GO:0017038 protein import; GO:0044699 single-organism process; GO:0051169 nuclear transport; GO:0036503 ERAD pathway; GO:0044237 cellular metabolic process; GO:0030968 endoplasmic reticulum unfolded protein response; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0035966 response to topologically incorrect protein; GO:0051649 establishment of localization in cell; GO:0030433 ubiquitin-dependent ERAD pathway; GO:0007154 cell communication; GO:0070972 protein localization to endoplasmic reticulum; GO:0044093 positive regulation of molecular function; GO:0065002 intracellular protein transmembrane transport; GO:0033365 protein localization to organelle; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0006606 protein import into nucleus; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0070887 cellular response to chemical stimulus; GO:0044765 single-organism transport; GO:0051716 cellular response to stimulus; GO:0030970 retrograde protein transport, ER to cytosol; GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0072657 protein localization to membrane; GO:0071806 protein transmembrane transport; GO:0044763 single-organism cellular process; GO:1903513 endoplasmic reticulum to cytosol transport; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0045047 protein targeting to ER; GO:0023052 signaling; GO:1902582 single-organism intracellular transport; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0030163 protein catabolic process; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0043087 regulation of GTPase activity; GO:0065009 regulation of molecular function; GO:0006913 nucleocytoplasmic transport; GO:0006620 posttranslational protein targeting to membrane; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0046907 intracellular transport; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0035967 cellular response to topologically incorrect protein; GO:0034976 response to endoplasmic reticulum stress; GO:0000060 protein import into nucleus, translocation; GO:0071310 cellular response to organic substance; GO:1902593 single-organism nuclear import; GO:0044267 cellular protein metabolic process; GO:0036498 IRE1-mediated unfolded protein response; GO:0006613 cotranslational protein targeting to membrane; GO:0050896 response to stimulus; GO:0010498 proteasomal protein catabolic process; GO:0031204 posttranslational protein targeting to membrane, translocation; GO:0071704 organic substance metabolic process; GO:1902578 single-organism localization; GO:0051345 positive regulation of hydrolase activity; GO:0006886 intracellular protein transport; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0044248 cellular catabolic process; GO:0044744 protein targeting to nucleus; GO:0006508 proteolysis; GO:1902580 single-organism cellular localization; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0090150 establishment of protein localization to membrane; GO:0043632 modification-dependent macromolecule catabolic process; GO:0006986 response to unfolded protein; GO:0044265 cellular macromolecule catabolic process; GO:0032527 protein exit from endoplasmic reticulum; GO:0034620 cellular response to unfolded protein; GO:0006950 response to stress; GO:0019941 modification-dependent protein catabolic process; GO:0043547 positive regulation of GTPase activity; GO:0044712 single-organism catabolic process; GO:0071702 organic substance transport; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0051641 cellular localization; GO:0043085 positive regulation of catalytic activity; GO:0045184 establishment of protein localization; GO:0055085 transmembrane transport; GO:0070727 cellular macromolecule localization; GO:0051170 nuclear import; GO:0009057 macromolecule catabolic process; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0051179 localization; GO:0034504 protein localization to nucleus; GO:0009056 catabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0030867 rough endoplasmic reticulum membrane; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0005791 rough endoplasmic reticulum; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0031205 endoplasmic reticulum Sec complex; GO:0005829 cytosol; GO:0016021 integral component of membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044432 endoplasmic reticulum part; GO:0071256 translocon complex; GO:0043234 protein complex; GO:0005784 Sec61 translocon complex; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0048408 epidermal growth factor binding; GO:0005086 ARF guanyl-nucleotide exchange factor activity; GO:0005085 guanyl-nucleotide exchange factor activity; GO:0019838 growth factor binding; GO:0042562 hormone binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0098772 molecular function regulator; ","K09481","SEC61B; protein transport protein SEC61 subunit beta","hsa03060 Protein export - Homo sapiens (human); hsa05110 Vibrio cholerae infection - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); "]
["P60520","Gamma-aminobutyric acid receptor-associated protein-like 2 OS=Homo sapiens OX=9606 GN=GABARAPL2","GABARAPL2",13.667,7.0797,22.2,3,4,3,0.923,1,1.023,0.947,1.012,1.05,1.021,0.651,"cytoplasm\r","GO:0044699 single-organism process; GO:0006914 autophagy; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0044093 positive regulation of molecular function; GO:0007033 vacuole organization; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:1903362 regulation of cellular protein catabolic process; GO:0016236 macroautophagy; GO:0080090 regulation of primary metabolic process; GO:0006891 intra-Golgi vesicle-mediated transport; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0031323 regulation of cellular metabolic process; GO:1903363 negative regulation of cellular protein catabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0006810 transport; GO:1902589 single-organism organelle organization; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:0043462 regulation of ATPase activity; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0061136 regulation of proteasomal protein catabolic process; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0032781 positive regulation of ATPase activity; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0042177 negative regulation of protein catabolic process; GO:1903051 negative regulation of proteolysis involved in cellular protein catabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0048193 Golgi vesicle transport; GO:0097352 autophagosome maturation; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:1901799 negative regulation of proteasomal protein catabolic process; GO:0051345 positive regulation of hydrolase activity; GO:0044248 cellular catabolic process; GO:0009895 negative regulation of catabolic process; GO:0042176 regulation of protein catabolic process; GO:0009987 cellular process; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0045861 negative regulation of proteolysis; GO:0016192 vesicle-mediated transport; GO:0048284 organelle fusion; GO:0071702 organic substance transport; GO:0030162 regulation of proteolysis; GO:0009892 negative regulation of metabolic process; GO:0043085 positive regulation of catalytic activity; GO:0045184 establishment of protein localization; GO:0031330 negative regulation of cellular catabolic process; GO:0097576 vacuole fusion; GO:0006996 organelle organization; GO:0051246 regulation of protein metabolic process; GO:0061024 membrane organization; GO:0051248 negative regulation of protein metabolic process; GO:0051179 localization; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0005776 autophagosome; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005622 intracellular; GO:0044464 cell part; GO:0044437 vacuolar part; GO:0098805 whole membrane; GO:0005773 vacuole; GO:0044431 Golgi apparatus part; GO:0005774 vacuolar membrane; GO:0005794 Golgi apparatus; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0000421 autophagosome membrane; ","GO:0000149 SNARE binding; GO:0050811 GABA receptor binding; GO:0008092 cytoskeletal protein binding; GO:0031625 ubiquitin protein ligase binding; GO:0005102 receptor binding; GO:0051117 ATPase binding; GO:0008017 microtubule binding; GO:0005488 binding; GO:0015631 tubulin binding; GO:0048487 beta-tubulin binding; GO:0005515 protein binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0019899 enzyme binding; ","K08341","GABARAP; GABA(A) receptor-associated protein","hsa04371 Apelin signaling pathway - Homo sapiens (human); hsa04727 GABAergic synapse - Homo sapiens (human); hsa04137 Mitophagy - animal - Homo sapiens (human); hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human); hsa05167 Kaposi's sarcoma-associated herpesvirus infection - Homo sapiens (human); hsa04068 FoxO signaling pathway - Homo sapiens (human); hsa04140 Autophagy - animal - Homo sapiens (human); hsa04136 Autophagy - other - Homo sapiens (human); ","IPR029071; ","Ubiquitin-related domain; \r"]
["P60842","Eukaryotic initiation factor 4A-I OS=Homo sapiens OX=9606 GN=EIF4A1","EIF4A1",46.153,166.74,43.1,22,56,10,0.812,0.77,0.807,1.209,1.203,1.216,1.519,1.82e-05,"nucleus\r","GO:0006518 peptide metabolic process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0006413 translational initiation; GO:1901361 organic cyclic compound catabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0006412 translation; GO:0044419 interspecies interaction between organisms; GO:0010468 regulation of gene expression; GO:0043043 peptide biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0043603 cellular amide metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051704 multi-organism process; GO:0006401 RNA catabolic process; GO:0016070 RNA metabolic process; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0016071 mRNA metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0044267 cellular protein metabolic process; GO:0048519 negative regulation of biological process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0016032 viral process; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0010501 RNA secondary structure unwinding; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0006807 nitrogen compound metabolic process; GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0009056 catabolic process; GO:0065007 biological regulation; GO:0046700 heterocycle catabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0031012 extracellular matrix; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0016281 eukaryotic translation initiation factor 4F complex; ","GO:0000339 RNA cap binding; GO:1901265 nucleoside phosphate binding; GO:0008026 ATP-dependent helicase activity; GO:0003743 translation initiation factor activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0016887 ATPase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0003729 mRNA binding; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0004004 ATP-dependent RNA helicase activity; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003723 RNA binding; GO:0070035 purine NTP-dependent helicase activity; GO:0005524 ATP binding; GO:0004386 helicase activity; GO:0003725 double-stranded RNA binding; GO:0008186 RNA-dependent ATPase activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0008135 translation factor activity, RNA binding; GO:0097367 carbohydrate derivative binding; GO:0003724 RNA helicase activity; GO:0042623 ATPase activity, coupled; GO:0003676 nucleic acid binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; ","K03257","EIF4A; translation initiation factor 4A","hsa03013 RNA transport - Homo sapiens (human); ","IPR014014; IPR011545; IPR014001; IPR027417; IPR001650; ","\"RNA helicase, DEAD-box type, Q motif; DEAD/DEAH box helicase domain; Helicase superfamily 1/2, ATP-binding domain; P-loop containing nucleoside triphosphate hydrolase; Helicase, C-terminal; \"\r"]
["P60900","Proteasome subunit alpha type-6 OS=Homo sapiens OX=9606 GN=PSMA6","PSMA6",27.399,84.883,47.2,11,24,11,0.97,0.96,0.948,1.036,1.07,1.068,1.103,1.4E-3,"cytoplasm\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0002220 innate immune response activating cell surface receptor signaling pathway; GO:0007166 cell surface receptor signaling pathway; GO:0010608 posttranscriptional regulation of gene expression; GO:0051443 positive regulation of ubiquitin-protein transferase activity; GO:0031347 regulation of defense response; GO:0071345 cellular response to cytokine stimulus; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:1903364 positive regulation of cellular protein catabolic process; GO:0008152 metabolic process; GO:0044093 positive regulation of molecular function; GO:0090263 positive regulation of canonical Wnt signaling pathway; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0051347 positive regulation of transferase activity; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0016055 Wnt signaling pathway; GO:1903362 regulation of cellular protein catabolic process; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0006521 regulation of cellular amino acid metabolic process; GO:0002758 innate immune response-activating signal transduction; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0010972 negative regulation of G2/M transition of mitotic cell cycle; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0060828 regulation of canonical Wnt signaling pathway; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0033209 tumor necrosis factor-mediated signaling pathway; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0000165 MAPK cascade; GO:1903506 regulation of nucleic acid-templated transcription; GO:2000058 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0019884 antigen processing and presentation of exogenous antigen; GO:1901575 organic substance catabolic process; GO:0051092 positive regulation of NF-kappaB transcription factor activity; GO:0010948 negative regulation of cell cycle process; GO:0007267 cell-cell signaling; GO:0002223 stimulatory C-type lectin receptor signaling pathway; GO:0032269 negative regulation of cellular protein metabolic process; GO:0051090 regulation of sequence-specific DNA binding transcription factor activity; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0030163 protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0060071 Wnt signaling pathway, planar cell polarity pathway; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:0002682 regulation of immune system process; GO:0006464 cellular protein modification process; GO:0031145 anaphase-promoting complex-dependent catabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016310 phosphorylation; GO:0033554 cellular response to stress; GO:0007346 regulation of mitotic cell cycle; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0051239 regulation of multicellular organismal process; GO:0043487 regulation of RNA stability; GO:0000209 protein polyubiquitination; GO:0031349 positive regulation of defense response; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0009889 regulation of biosynthetic process; GO:1901987 regulation of cell cycle phase transition; GO:0009896 positive regulation of catabolic process; GO:0043620 regulation of DNA-templated transcription in response to stress; GO:0070482 response to oxygen levels; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0044248 cellular catabolic process; GO:0010389 regulation of G2/M transition of mitotic cell cycle; GO:0042176 regulation of protein catabolic process; GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; GO:0038093 Fc receptor signaling pathway; GO:0050778 positive regulation of immune response; GO:0009966 regulation of signal transduction; GO:0023014 signal transduction by protein phosphorylation; GO:0071456 cellular response to hypoxia; GO:0038061 NIK/NF-kappaB signaling; GO:0002253 activation of immune response; GO:0006950 response to stress; GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; GO:0016567 protein ubiquitination; GO:0032101 regulation of response to external stimulus; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress; GO:1904666 regulation of ubiquitin protein ligase activity; GO:1903321 negative regulation of protein modification by small protein conjugation or removal; GO:0055085 transmembrane transport; GO:0051247 positive regulation of protein metabolic process; GO:0051438 regulation of ubiquitin-protein transferase activity; GO:0031398 positive regulation of protein ubiquitination; GO:0032446 protein modification by small protein conjugation; GO:0006793 phosphorus metabolic process; GO:0030111 regulation of Wnt signaling pathway; GO:0031325 positive regulation of cellular metabolic process; GO:0030177 positive regulation of Wnt signaling pathway; GO:1904668 positive regulation of ubiquitin protein ligase activity; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0036293 response to decreased oxygen levels; GO:0051179 localization; GO:0043412 macromolecule modification; GO:0048584 positive regulation of response to stimulus; GO:0050793 regulation of developmental process; GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process; GO:0051444 negative regulation of ubiquitin-protein transferase activity; GO:0070646 protein modification by small protein removal; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0031331 positive regulation of cellular catabolic process; GO:0090090 negative regulation of canonical Wnt signaling pathway; GO:0044699 single-organism process; GO:0031400 negative regulation of protein modification process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0035567 non-canonical Wnt signaling pathway; GO:0031396 regulation of protein ubiquitination; GO:1905330 regulation of morphogenesis of an epithelium; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0045930 negative regulation of mitotic cell cycle; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0045088 regulation of innate immune response; GO:1901991 negative regulation of mitotic cell cycle phase transition; GO:0009893 positive regulation of metabolic process; GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0034612 response to tumor necrosis factor; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0051726 regulation of cell cycle; GO:0070887 cellular response to chemical stimulus; GO:0050851 antigen receptor-mediated signaling pathway; GO:0010468 regulation of gene expression; GO:0030178 negative regulation of Wnt signaling pathway; GO:0034097 response to cytokine; GO:0031326 regulation of cellular biosynthetic process; GO:0048002 antigen processing and presentation of peptide antigen; GO:0048522 positive regulation of cellular process; GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0051348 negative regulation of transferase activity; GO:0070647 protein modification by small protein conjugation or removal; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0198738 cell-cell signaling by wnt; GO:0010565 regulation of cellular ketone metabolic process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0036211 protein modification process; GO:2000026 regulation of multicellular organismal development; GO:0090175 regulation of establishment of planar polarity; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0045786 negative regulation of cell cycle; GO:1904667 negative regulation of ubiquitin protein ligase activity; GO:0002218 activation of innate immune response; GO:0044257 cellular protein catabolic process; GO:0071356 cellular response to tumor necrosis factor; GO:1901988 negative regulation of cell cycle phase transition; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0016579 protein deubiquitination; GO:0050896 response to stimulus; GO:0010498 proteasomal protein catabolic process; GO:0071704 organic substance metabolic process; GO:1903322 positive regulation of protein modification by small protein conjugation or removal; GO:0045862 positive regulation of proteolysis; GO:2000027 regulation of organ morphogenesis; GO:0006468 protein phosphorylation; GO:0023056 positive regulation of signaling; GO:0001666 response to hypoxia; GO:0002757 immune response-activating signal transduction; GO:0006508 proteolysis; GO:0010647 positive regulation of cell communication; GO:0071453 cellular response to oxygen levels; GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:0019221 cytokine-mediated signaling pathway; GO:0009987 cellular process; GO:0033238 regulation of cellular amine metabolic process; GO:0031397 negative regulation of protein ubiquitination; GO:0043632 modification-dependent macromolecule catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0045089 positive regulation of innate immune response; GO:0006355 regulation of transcription, DNA-templated; GO:0035556 intracellular signal transduction; GO:0019941 modification-dependent protein catabolic process; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition; GO:0031401 positive regulation of protein modification process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia; GO:1902749 regulation of cell cycle G2/M phase transition; GO:0043488 regulation of mRNA stability; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0019882 antigen processing and presentation; GO:0050852 T cell receptor signaling pathway; GO:0051246 regulation of protein metabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0002684 positive regulation of immune system process; GO:0009057 macromolecule catabolic process; GO:0038095 Fc-epsilon receptor signaling pathway; GO:0050727 regulation of inflammatory response; GO:0051248 negative regulation of protein metabolic process; GO:0022402 cell cycle process; GO:0045732 positive regulation of protein catabolic process; GO:0009967 positive regulation of signal transduction; GO:1902750 negative regulation of cell cycle G2/M phase transition; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0036294 cellular response to decreased oxygen levels; GO:0065007 biological regulation; ","GO:0044421 extracellular region part; GO:0030016 myofibril; GO:0031982 vesicle; GO:0000932 P-body; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:1905369 endopeptidase complex; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0043292 contractile fiber; GO:1905368 peptidase complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0019773 proteasome core complex, alpha-subunit complex; GO:0000502 proteasome complex; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0099081 supramolecular polymer; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0016363 nuclear matrix; GO:0030017 sarcomere; GO:0035770 ribonucleoprotein granule; GO:0005839 proteasome core complex; GO:0044449 contractile fiber part; GO:0034399 nuclear periphery; GO:1990904 ribonucleoprotein complex; GO:0043234 protein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0005844 polysome; GO:0044428 nuclear part; ","GO:0003723 RNA binding; GO:0008233 peptidase activity; GO:1901265 nucleoside phosphate binding; GO:0043167 ion binding; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0004175 endopeptidase activity; GO:0004298 threonine-type endopeptidase activity; GO:0070003 threonine-type peptidase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0051059 NF-kappaB binding; GO:0043168 anion binding; GO:0008134 transcription factor binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K02730","PSMA6; 20S proteasome subunit alpha 1 [EC:3.4.25.1]","hsa03050 Proteasome - Homo sapiens (human); ","IPR000426; IPR029055; ","\"Proteasome alpha-subunit, N-terminal domain; Nucleophile aminohydrolases, N-terminal; \"\r"]
["P60953","Cell division control protein 42 homolog OS=Homo sapiens OX=9606 GN=CDC42","CDC42",21.258,34.742,29.8,5,18,5,0.999,0.948,0.964,0.977,1.044,1.031,1.048,0.139,"cytoplasm\r",{"$cut":{"chars":21853,"head":"GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0002694 regulation of leukocyte activation; GO:0010941 regulation of cell death; GO:0046847 filopodium assembly; GO:0032872 regulation of stress-activated MAPK cascade; GO:0048732 gland development; GO:0031424 keratinization; GO:1901185 negative regulation of ERBB signaling pathway; GO:0009891 positive regulation of biosynthetic process; GO:0043523 regulation of neuron apoptotic process; GO:0044237 cellular metabolic process; GO:0010564 regulation of cell cycle process; GO:0045927 positive regulation of growth; GO:0007097 nuclear migration; GO:0001558 regulation of cell growth; GO:0021762 substantia nigra development; GO:0009913 epidermal cell differentiation; GO:0008152 metabolic process; GO:0001525 angiogenesis; GO:0044033 multi-organism metabolic process; GO:0044093 positive regulation of molecular function; GO:0034332 adherens junction organization; GO:0008544 epidermis development; GO:0090068 positive regulation of cell cycle process; GO:0016055 Wnt signaling pathway; GO:0033138 positive regulation of peptidyl-serine phosphorylation; GO:0051147 regulation of muscle cell differentiation; GO:0031333 negative regulation of protein complex assembly; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0002064 epithelial cell development; GO:0043588 skin development; GO:0051054 positive regulation of DNA metabolic process; GO:0030307 positive regulation of cell growth; GO:0080090 regulation of primary metabolic process; GO:0060537 muscle tissue development; GO:0048699 generation of neurons; GO:1900026 positive regulation of substrate adhesion-dependent cell spreading; GO:0044763 single-organism cellular process; GO:0002520 immune system development; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0048870 cell motility; GO:0051704 multi-organism process; GO:0051683 establishment of Golgi localization; GO:0010811 positive regulation of cell-substrate adhesion; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0007267 cell-cell signaling; GO:0080135 regulation of cellular response to stress; GO:0007030 Golgi organization; GO:0031274 positive regulation of pseudopodium assembly; GO:0032874 positive regulation of stress-activated MAPK cascade; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0098602 single organism cell adhesion; GO:0051149 positive regulation of muscle cell differentiation; GO:0060071 Wnt signaling pathway, planar cell polarity pathway; GO:0051223 regulation of protein transport; GO:0039694 viral RNA genome replication; GO:0071338 positive regulation of hair follicle cell proliferation; GO:0048010 vascular endothelial growth factor receptor signaling pathway; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0030855 epithelial cell differentiation; GO:0072359 circulatory system development; GO:0051640 organelle localization; GO:0002009 morphogenesis of an epithelium; GO:0044707 single-multicellular organism process; GO:0097061 dendritic spine organization; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0042303 molting cycle; GO:0003334 keratinocyte development; GO:0048519 negative regulation of biological process; GO:0051988 regulation of attachment of spindle microtubules to kinetochore; GO:0030705 cytoskeleton-dependent intracellular transport; GO:0032467 positive regulation of cytokinesis; GO:0009653 anatomical structure morphogenesis; GO:0050867 positive regulation of cell activation; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:1902580 single-organism cellular localization; GO:0042176 regulation of protein catabolic "}},"GO:0030425 dendrite; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0051233 spindle midzone; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0043025 neuronal cell body; GO:0032991 macromolecular complex; GO:0098858 actin-based cell projection; GO:0000322 storage vacuole; GO:0005623 cell; GO:0043197 dendritic spine; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0031256 leading edge membrane; GO:0043209 myelin sheath; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0030175 filopodium; GO:0043005 neuron projection; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0005789 endoplasmic reticulum membrane; GO:0045177 apical part of cell; GO:0005924 cell-substrate adherens junction; GO:0031252 cell leading edge; GO:0042995 cell projection; GO:0044430 cytoskeletal part; GO:0030496 midbody; GO:0070161 anchoring junction; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0098794 postsynapse; GO:0005773 vacuole; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043230 extracellular organelle; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005911 cell-cell junction; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0072686 mitotic spindle; GO:0005856 cytoskeleton; GO:0005815 microtubule organizing center; GO:0044309 neuron spine; GO:0015630 microtubule cytoskeleton; GO:0044464 cell part; GO:0044425 membrane part; GO:1903561 extracellular vesicle; GO:0005912 adherens junction; GO:0044431 Golgi apparatus part; GO:0030141 secretory granule; GO:0044456 synapse part; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0005819 spindle; GO:0045202 synapse; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0044459 plasma membrane part; GO:0044432 endoplasmic reticulum part; GO:0035770 ribonucleoprotein granule; GO:0044297 cell body; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0005102 receptor binding; GO:0019901 protein kinase binding; GO:0034191 apolipoprotein A-I receptor binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0031996 thioesterase binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0061630 ubiquitin protein ligase activity; GO:0042802 identical protein binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0003924 GTPase activity; GO:0043168 anion binding; GO:0019001 guanyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005525 GTP binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0051022 Rho GDP-dissociation inhibitor binding; GO:0030742 GTP-dependent protein binding; GO:0019787 ubiquitin-like protein transferase activity; GO:0034190 apolipoprotein receptor binding; GO:0051021 GDP-dissociation inhibitor binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0061659 ubiquitin-like protein ligase activity; GO:0017111 nucleoside-triphosphatase activity; GO:0019900 kinase binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0031435 mitogen-activated protein kinase kinase kinase binding; GO:0004842 ubiquitin-protein transferase activity; GO:0032555 purine ribonucleotide binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019899 enzyme binding; GO:0036094 small molecule binding; ","K04393","CDC42; cell division control protein 42","hsa05120 Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human); hsa05100 Bacterial invasion of epithelial cells - Homo sapiens (human); hsa05132 Salmonella infection - Homo sapiens (human); hsa04015 Rap1 signaling pathway - Homo sapiens (human); hsa04722 Neurotrophin signaling pathway - Homo sapiens (human); hsa04530 Tight junction - Homo sapiens (human); hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human); hsa04370 VEGF signaling pathway - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa04014 Ras signaling pathway - Homo sapiens (human); hsa05211 Renal cell carcinoma - Homo sapiens (human); hsa04670 Leukocyte transendothelial migration - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa04010 MAPK signaling pathway - Homo sapiens (human); hsa04144 Endocytosis - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa04660 T cell receptor signaling pathway - Homo sapiens (human); hsa05131 Shigellosis - Homo sapiens (human); hsa04062 Chemokine signaling pathway - Homo sapiens (human); hsa04666 Fc gamma R-mediated phagocytosis - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa04912 GnRH signaling pathway - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa04933 AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa05203 Viral carcinogenesis - Homo sapiens (human); hsa04520 Adherens junction - Homo sapiens (human); hsa04360 Axon guidance - Homo sapiens (human); hsa05212 Pancreatic cancer - Homo sapiens (human); ","IPR005225; IPR027417; ","Small GTP-binding protein domain; P-loop containing nucleoside triphosphate hydrolase; \r"]
["P60981","Destrin OS=Homo sapiens OX=9606 GN=DSTN","DSTN",18.506,48.872,48.5,11,30,10,1.06,1.035,0.92,0.99,1.015,0.969,0.986,0.807,"mitochondria\r","GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0065008 regulation of biological quality; GO:0032956 regulation of actin cytoskeleton organization; GO:0043243 positive regulation of protein complex disassembly; GO:0007015 actin filament organization; GO:0044699 single-organism process; GO:0030832 regulation of actin filament length; GO:0043241 protein complex disassembly; GO:0051130 positive regulation of cellular component organization; GO:0030036 actin cytoskeleton organization; GO:0032535 regulation of cellular component size; GO:0030043 actin filament fragmentation; GO:0043624 cellular protein complex disassembly; GO:0051493 regulation of cytoskeleton organization; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0051014 actin filament severing; GO:0051261 protein depolymerization; GO:0030836 positive regulation of actin filament depolymerization; GO:0071822 protein complex subunit organization; GO:0051495 positive regulation of cytoskeleton organization; GO:1901879 regulation of protein depolymerization; GO:0044763 single-organism cellular process; GO:0032984 macromolecular complex disassembly; GO:0008154 actin polymerization or depolymerization; GO:0048522 positive regulation of cellular process; GO:0033043 regulation of organelle organization; GO:0032970 regulation of actin filament-based process; GO:0030042 actin filament depolymerization; GO:1901881 positive regulation of protein depolymerization; GO:0048518 positive regulation of biological process; GO:0043933 macromolecular complex subunit organization; GO:1902589 single-organism organelle organization; GO:0008064 regulation of actin polymerization or depolymerization; GO:0050789 regulation of biological process; GO:0010638 positive regulation of organelle organization; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0022411 cellular component disassembly; GO:0090066 regulation of anatomical structure size; GO:1902905 positive regulation of supramolecular fiber organization; GO:0043244 regulation of protein complex disassembly; GO:0030834 regulation of actin filament depolymerization; GO:0051128 regulation of cellular component organization; GO:0097435 supramolecular fiber organization; GO:1902903 regulation of supramolecular fiber organization; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0005938 cell cortex; GO:0043232 intracellular non-membrane-bounded organelle; GO:0071944 cell periphery; GO:0044430 cytoskeletal part; GO:0099568 cytoplasmic region; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0030863 cortical cytoskeleton; GO:0030864 cortical actin cytoskeleton; GO:0044424 intracellular part; GO:0005623 cell; GO:0015629 actin cytoskeleton; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0044448 cell cortex part; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0051015 actin filament binding; GO:0008092 cytoskeletal protein binding; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0003779 actin binding; GO:0005515 protein binding; GO:0032403 protein complex binding; ","K10363",null,null,"IPR029006; IPR002108; ","ADF-H/Gelsolin-like domain; Actin-depolymerising factor homology domain; \r"]
["P61009","Signal peptidase complex subunit 3 OS=Homo sapiens OX=9606 GN=SPCS3","SPCS3",20.313,29.833,17.8,3,5,3,1.037,0.991,0.975,0.992,0.906,1.029,0.975,0.56,"extracellular\r","GO:0046907 intracellular transport; GO:0072594 establishment of protein localization to organelle; GO:0006518 peptide metabolic process; GO:0006465 signal peptide processing; GO:0044267 cellular protein metabolic process; GO:0016485 protein processing; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0071704 organic substance metabolic process; GO:0006605 protein targeting; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0070972 protein localization to endoplasmic reticulum; GO:0006886 intracellular protein transport; GO:0034641 cellular nitrogen compound metabolic process; GO:0006508 proteolysis; GO:0033365 protein localization to organelle; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0034613 cellular protein localization; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0009987 cellular process; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0045047 protein targeting to ER; GO:0043603 cellular amide metabolic process; GO:0044238 primary metabolic process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:0070727 cellular macromolecule localization; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0051179 localization; GO:0051604 protein maturation; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0043229 intracellular organelle; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0032991 macromolecular complex; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:1902494 catalytic complex; GO:0044432 endoplasmic reticulum part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005787 signal peptidase complex; GO:1905368 peptidase complex; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; ","GO:0008233 peptidase activity; GO:0016787 hydrolase activity; GO:0003824 catalytic activity; ","K12948","SPCS3; signal peptidase complex subunit 3 [EC:3.4.-.-]","hsa03060 Protein export - Homo sapiens (human); "]
["P61011","Signal recognition particle 54 kDa protein OS=Homo sapiens OX=9606 GN=SRP54","SRP54",55.704,51.853,20.8,9,12,9,0.821,0.925,0.877,1.058,1.069,1.125,1.24,0.0054,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0072594 establishment of protein localization to organelle; GO:0006613 cotranslational protein targeting to membrane; GO:0050896 response to stimulus; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0042493 response to drug; GO:0006612 protein targeting to membrane; GO:0051649 establishment of localization in cell; GO:0022607 cellular component assembly; GO:0070972 protein localization to endoplasmic reticulum; GO:0065003 macromolecular complex assembly; GO:0065002 intracellular protein transmembrane transport; GO:0006886 intracellular protein transport; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0033365 protein localization to organelle; GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition; GO:0034613 cellular protein localization; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0009987 cellular process; GO:0090150 establishment of protein localization to membrane; GO:0006461 protein complex assembly; GO:0043623 cellular protein complex assembly; GO:0034622 cellular macromolecular complex assembly; GO:0071822 protein complex subunit organization; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation; GO:0072657 protein localization to membrane; GO:0071806 protein transmembrane transport; GO:0071702 organic substance transport; GO:0045047 protein targeting to ER; GO:0043933 macromolecular complex subunit organization; GO:0051641 cellular localization; GO:0006810 transport; GO:0045184 establishment of protein localization; GO:0055085 transmembrane transport; GO:0070727 cellular macromolecule localization; GO:0042221 response to chemical; GO:0070271 protein complex biogenesis; GO:0051179 localization; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0048500 signal recognition particle; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005786 signal recognition particle, endoplasmic reticulum targeting; GO:0016607 nuclear speck; GO:0005622 intracellular; GO:0044464 cell part; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0005048 signal sequence binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0019003 GDP binding; GO:0042277 peptide binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0003924 GTPase activity; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0030942 endoplasmic reticulum signal peptide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0017076 purine nucleotide binding; GO:0003723 RNA binding; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0033218 amide binding; GO:0008144 drug binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0008312 7S RNA binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003676 nucleic acid binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0032561 guanyl ribonucleotide binding; GO:0043021 ribonucleoprotein complex binding; GO:0036094 small molecule binding; ","K03106","SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]","hsa03060 Protein export - Homo sapiens (human); ","IPR003593; IPR013822; IPR004125; IPR027417; IPR000897; ","\"AAA+ ATPase domain; Signal recognition particle, SRP54 subunit, helical bundle; Signal recognition particle, SRP54 subunit, M-domain; P-loop containing nucleoside triphosphate hydrolase; Signal recognition particle, SRP54 subunit, GTPase domain; \"\r"]
["P61026","Ras-related protein Rab-10 OS=Homo sapiens OX=9606 GN=RAB10","RAB10",22.541,47.601,49.5,12,26,10,0.907,0.956,0.872,1.124,1.111,1.054,1.203,0.0051,"cytoplasm\r","GO:0044700 single organism signaling; GO:0001738 morphogenesis of a polarized epithelium; GO:0045321 leukocyte activation; GO:0090002 establishment of protein localization to plasma membrane; GO:0032989 cellular component morphogenesis; GO:0015031 protein transport; GO:0022610 biological adhesion; GO:0070972 protein localization to endoplasmic reticulum; GO:0009719 response to endogenous stimulus; GO:0007155 cell adhesion; GO:0009306 protein secretion; GO:0033365 protein localization to organelle; GO:0008104 protein localization; GO:1901652 response to peptide; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0006904 vesicle docking involved in exocytosis; GO:0072657 protein localization to membrane; GO:0048699 generation of neurons; GO:0007405 neuroblast proliferation; GO:0044763 single-organism cellular process; GO:0048812 neuron projection morphogenesis; GO:0007264 small GTPase mediated signal transduction; GO:0007009 plasma membrane organization; GO:0007163 establishment or maintenance of cell polarity; GO:0032501 multicellular organismal process; GO:0000902 cell morphogenesis; GO:0006810 transport; GO:0010243 response to organonitrogen compound; GO:0098722 asymmetric stem cell division; GO:1901698 response to nitrogen compound; GO:0032869 cellular response to insulin stimulus; GO:0051301 cell division; GO:0030855 epithelial cell differentiation; GO:0050794 regulation of cellular process; GO:0002009 morphogenesis of an epithelium; GO:0044707 single-multicellular organism process; GO:0002283 neutrophil activation involved in immune response; GO:0055059 asymmetric neuroblast division; GO:1901700 response to oxygen-containing compound; GO:0030859 polarized epithelial cell differentiation; GO:1990778 protein localization to cell periphery; GO:0072089 stem cell proliferation; GO:0009653 anatomical structure morphogenesis; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0007409 axonogenesis; GO:1902580 single-organism cellular localization; GO:0007275 multicellular organism development; GO:0034613 cellular protein localization; GO:0090150 establishment of protein localization to membrane; GO:0036445 neuronal stem cell division; GO:0045196 establishment or maintenance of neuroblast polarity; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0071702 organic substance transport; GO:0008283 cell proliferation; GO:0010033 response to organic substance; GO:0017145 stem cell division; GO:0048278 vesicle docking; GO:0002263 cell activation involved in immune response; GO:0045184 establishment of protein localization; GO:0045165 cell fate commitment; GO:0030182 neuron differentiation; GO:0045055 regulated exocytosis; GO:0072659 protein localization to plasma membrane; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0001775 cell activation; GO:0006955 immune response; GO:0006892 post-Golgi vesicle-mediated transport; GO:0051179 localization; GO:0006887 exocytosis; GO:0010256 endomembrane system organization; GO:0048103 somatic stem cell division; GO:0072594 establishment of protein localization to organelle; GO:0048869 cellular developmental process; GO:0048666 neuron development; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0051234 establishment of localization; GO:0008105 asymmetric protein localization; GO:0061351 neural precursor cell proliferation; GO:0048729 tissue morphogenesis; GO:0008356 asymmetric cell division; GO:0007165 signal transduction; GO:1901653 cellular response to peptide; GO:0007154 cell communication; GO:0045200 establishment of neuroblast polarity; GO:0032990 cell part morphogenesis; GO:0006893 Golgi to plasma membrane transport; GO:0048858 cell projection morphogenesis; GO:0033036 macromolecule localization; GO:0070887 cellular response to chemical stimulus; GO:0055057 neuroblast division; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0097051 establishment of protein localization to endoplasmic reticulum membrane; GO:0009888 tissue development; GO:0002446 neutrophil mediated immunity; GO:0098609 cell-cell adhesion; GO:0023052 signaling; GO:0002444 myeloid leukocyte mediated immunity; GO:0071417 cellular response to organonitrogen compound; GO:0016197 endosomal transport; GO:0042221 response to chemical; GO:0032868 response to insulin; GO:0050789 regulation of biological process; GO:0043434 response to peptide hormone; GO:1901699 cellular response to nitrogen compound; GO:0030030 cell projection organization; GO:0032870 cellular response to hormone stimulus; GO:0032940 secretion by cell; GO:0043299 leukocyte degranulation; GO:0048856 anatomical structure development; GO:0007029 endoplasmic reticulum organization; GO:0016043 cellular component organization; GO:0002252 immune effector process; GO:0071310 cellular response to organic substance; GO:0071786 endoplasmic reticulum tubular network organization; GO:0048193 Golgi vesicle transport; GO:0050896 response to stimulus; GO:0022406 membrane docking; GO:0048468 cell development; GO:0000904 cell morphogenesis involved in differentiation; GO:0030154 cell differentiation; GO:0071375 cellular response to peptide hormone stimulus; GO:0030010 establishment of cell polarity; GO:0043001 Golgi to plasma membrane protein transport; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0098876 vesicle-mediated transport to the plasma membrane; GO:0035556 intracellular signal transduction; GO:0044802 single-organism membrane organization; GO:0031175 neuron projection development; GO:0043312 neutrophil degranulation; GO:0051641 cellular localization; GO:0002366 leukocyte activation involved in immune response; GO:0019882 antigen processing and presentation; GO:0061564 axon development; GO:0042119 neutrophil activation; GO:0070727 cellular macromolecule localization; GO:1901701 cellular response to oxygen-containing compound; GO:0071495 cellular response to endogenous stimulus; GO:0044767 single-organism developmental process; GO:0009725 response to hormone; GO:0061467 basolateral protein localization; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0005913 cell-cell adherens junction; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0098827 endoplasmic reticulum subcompartment; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0098791 Golgi subcompartment; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0005924 cell-substrate adherens junction; GO:0005929 cilium; GO:0010008 endosome membrane; GO:0042995 cell projection; GO:0030666 endocytic vesicle membrane; GO:0070161 anchoring junction; GO:0012506 vesicle membrane; GO:0044440 endosomal part; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0030667 secretory granule membrane; GO:0043230 extracellular organelle; GO:0005783 endoplasmic reticulum; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0031410 cytoplasmic vesicle; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0055038 recycling endosome membrane; GO:0005911 cell-cell junction; GO:0055037 recycling endosome; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0030670 phagocytic vesicle membrane; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0005768 endosome; GO:0030141 secretory granule; GO:0030139 endocytic vesicle; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0045335 phagocytic vesicle; GO:0005829 cytosol; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0071782 endoplasmic reticulum tubular network; GO:0044432 endoplasmic reticulum part; GO:0005802 trans-Golgi network; GO:0032593 insulin-responsive compartment; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; GO:0031984 organelle subcompartment; ","GO:1901265 nucleoside phosphate binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0031489 myosin V binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0098641 cadherin binding involved in cell-cell adhesion; GO:0016462 pyrophosphatase activity; GO:0019003 GDP binding; GO:0008092 cytoskeletal protein binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0003924 GTPase activity; GO:0032550 purine ribonucleoside binding; GO:0045296 cadherin binding; GO:0043168 anion binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0017076 purine nucleotide binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0098632 protein binding involved in cell-cell adhesion; GO:0050839 cell adhesion molecule binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0098631 protein binding involved in cell adhesion; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0032561 guanyl ribonucleotide binding; GO:0017022 myosin binding; GO:0036094 small molecule binding; ","K07903","RAB10; Ras-related protein Rab-10","hsa04144 Endocytosis - Homo sapiens (human); hsa04152 AMPK signaling pathway - Homo sapiens (human); ","IPR005225; IPR027417; ","Small GTP-binding protein domain; P-loop containing nucleoside triphosphate hydrolase; \r"]
["P61081","NEDD8-conjugating enzyme Ubc12 OS=Homo sapiens OX=9606 GN=UBE2M","UBE2M",20.9,32.878,25.1,4,6,4,0.998,0.921,0.996,1.004,1.024,1.017,1.045,0.177,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0007166 cell surface receptor signaling pathway; GO:0071310 cellular response to organic substance; GO:0043067 regulation of programmed cell death; GO:0043523 regulation of neuron apoptotic process; GO:0071560 cellular response to transforming growth factor beta stimulus; GO:0044267 cellular protein metabolic process; GO:0043065 positive regulation of apoptotic process; GO:0044699 single-organism process; GO:0071363 cellular response to growth factor stimulus; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:1901216 positive regulation of neuron death; GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0009719 response to endogenous stimulus; GO:0070848 response to growth factor; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009987 cellular process; GO:1901214 regulation of neuron death; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0070887 cellular response to chemical stimulus; GO:0038061 NIK/NF-kappaB signaling; GO:0051716 cellular response to stimulus; GO:0045116 protein neddylation; GO:0016567 protein ubiquitination; GO:0035556 intracellular signal transduction; GO:0007179 transforming growth factor beta receptor signaling pathway; GO:0048522 positive regulation of cellular process; GO:0010033 response to organic substance; GO:0070647 protein modification by small protein conjugation or removal; GO:0071559 response to transforming growth factor beta; GO:0023052 signaling; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0010942 positive regulation of cell death; GO:0043525 positive regulation of neuron apoptotic process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032446 protein modification by small protein conjugation; GO:0071495 cellular response to endogenous stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:0042981 regulation of apoptotic process; GO:0043068 positive regulation of programmed cell death; GO:0065007 biological regulation; ","GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0019788 NEDD8 transferase activity; GO:0016874 ligase activity; GO:0005515 protein binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0019787 ubiquitin-like protein transferase activity; GO:0018169 ribosomal S6-glutamic acid ligase activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0070739 protein-glutamic acid ligase activity; GO:0000166 nucleotide binding; GO:0016881 acid-amino acid ligase activity; GO:0016879 ligase activity, forming carbon-nitrogen bonds; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0004842 ubiquitin-protein transferase activity; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; ","K10579","UBE2M; ubiquitin-conjugating enzyme E2 M","hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human); ","IPR016135; IPR000608; ","Ubiquitin-conjugating enzyme/RWD-like; Ubiquitin-conjugating enzyme E2; \r"]
["P61158","Actin-related protein 3 OS=Homo sapiens OX=9606 GN=ACTR3","ACTR3",47.371,127.7,48.8,18,33,18,0.932,0.967,0.964,1.048,1.022,1.066,1.095,0.00586,"cytoplasm\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0030833 regulation of actin filament polymerization; GO:0034314 Arp2/3 complex-mediated actin nucleation; GO:0065008 regulation of biological quality; GO:0032273 positive regulation of protein polymerization; GO:0007166 cell surface receptor signaling pathway; GO:0022414 reproductive process; GO:0038094 Fc-gamma receptor signaling pathway; GO:0060271 cilium assembly; GO:0044699 single-organism process; GO:0030832 regulation of actin filament length; GO:0044782 cilium organization; GO:0006909 phagocytosis; GO:0016344 meiotic chromosome movement towards spindle pole; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0007165 signal transduction; GO:0008356 asymmetric cell division; GO:0050000 chromosome localization; GO:0030036 actin cytoskeleton organization; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0044702 single organism reproductive process; GO:0045010 actin nucleation; GO:0032535 regulation of cellular component size; GO:0032271 regulation of protein polymerization; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0051305 chromosome movement towards spindle pole; GO:0031334 positive regulation of protein complex assembly; GO:0051493 regulation of cytoskeleton organization; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0044765 single-organism transport; GO:0045132 meiotic chromosome segregation; GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis; GO:0051716 cellular response to stimulus; GO:0007059 chromosome segregation; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0048522 positive regulation of cellular process; GO:0007163 establishment or maintenance of cell polarity; GO:0051321 meiotic cell cycle; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0050776 regulation of immune response; GO:0006810 transport; GO:1902589 single-organism organelle organization; GO:0043254 regulation of protein complex assembly; GO:0050789 regulation of biological process; GO:0030030 cell projection organization; GO:0010638 positive regulation of organelle organization; GO:0048583 regulation of response to stimulus; GO:0002682 regulation of immune system process; GO:1902905 positive regulation of supramolecular fiber organization; GO:0002431 Fc receptor mediated stimulatory signaling pathway; GO:0051301 cell division; GO:0097435 supramolecular fiber organization; GO:1902903 regulation of supramolecular fiber organization; GO:0050794 regulation of cellular process; GO:0051640 organelle localization; GO:0000003 reproduction; GO:0016043 cellular component organization; GO:1903046 meiotic cell cycle process; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0002252 immune effector process; GO:0032956 regulation of actin cytoskeleton organization; GO:0051653 spindle localization; GO:0048285 organelle fission; GO:0007015 actin filament organization; GO:0044087 regulation of cellular component biogenesis; GO:0050896 response to stimulus; GO:0000910 cytokinesis; GO:0048013 ephrin receptor signaling pathway; GO:1902578 single-organism localization; GO:0070925 organelle assembly; GO:0002757 immune response-activating signal transduction; GO:1902580 single-organism cellular localization; GO:0038093 Fc receptor signaling pathway; GO:0007010 cytoskeleton organization; GO:0050778 positive regulation of immune response; GO:0009987 cellular process; GO:0002253 activation of immune response; GO:0051495 positive regulation of cytoskeleton organization; GO:0051303 establishment of chromosome localization; GO:0016192 vesicle-mediated transport; GO:0033043 regulation of organelle organization; GO:0002376 immune system process; GO:0032970 regulation of actin filament-based process; GO:0006897 endocytosis; GO:0051656 establishment of organelle localization; GO:0007017 microtubule-based process; GO:0030838 positive regulation of actin filament polymerization; GO:0048518 positive regulation of biological process; GO:0030031 cell projection assembly; GO:0051641 cellular localization; GO:0007018 microtubule-based movement; GO:0008064 regulation of actin polymerization or depolymerization; GO:0061640 cytoskeleton-dependent cytokinesis; GO:0098813 nuclear chromosome segregation; GO:0006996 organelle organization; GO:0002684 positive regulation of immune system process; GO:0061024 membrane organization; GO:0033206 meiotic cytokinesis; GO:0030029 actin filament-based process; GO:0000280 nuclear division; GO:0006928 movement of cell or subcellular component; GO:0090066 regulation of anatomical structure size; GO:0007126 meiotic nuclear division; GO:0051128 regulation of cellular component organization; GO:0022402 cell cycle process; GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0044089 positive regulation of cellular component biogenesis; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0098862 cluster of actin-based cell projections; GO:0005903 brush border; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005911 cell-cell junction; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0005885 Arp2/3 protein complex; GO:0005925 focal adhesion; GO:0044464 cell part; GO:0005622 intracellular; GO:0030027 lamellipodium; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0031252 cell leading edge; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0015629 actin cytoskeleton; GO:0043226 organelle; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0008092 cytoskeletal protein binding; GO:0005200 structural constituent of cytoskeleton; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0003779 actin binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0005198 structural molecule activity; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K18584","ACTR3; actin-related protein 3","hsa04530 Tight junction - Homo sapiens (human); "]
["P61160","Actin-related protein 2 OS=Homo sapiens OX=9606 GN=ACTR2","ACTR2",44.76,86.625,35,12,29,12,0.988,0.972,0.963,1.037,1.031,1.013,1.054,0.00688,"cytoplasm\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0007166 cell surface receptor signaling pathway; GO:0022414 reproductive process; GO:0060271 cilium assembly; GO:0030832 regulation of actin filament length; GO:0050877 neurological system process; GO:0044782 cilium organization; GO:0016344 meiotic chromosome movement towards spindle pole; GO:0007610 behavior; GO:0030036 actin cytoskeleton organization; GO:0051240 positive regulation of multicellular organismal process; GO:0044702 single organism reproductive process; GO:0032535 regulation of cellular component size; GO:0009719 response to endogenous stimulus; GO:0051493 regulation of cytoskeleton organization; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0007399 nervous system development; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0007059 chromosome segregation; GO:0048699 generation of neurons; GO:0031346 positive regulation of cell projection organization; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0007163 establishment or maintenance of cell polarity; GO:0032501 multicellular organismal process; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0010243 response to organonitrogen compound; GO:0007612 learning; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0060999 positive regulation of dendritic spine development; GO:0002682 regulation of immune system process; GO:1902905 positive regulation of supramolecular fiber organization; GO:0051301 cell division; GO:0051094 positive regulation of developmental process; GO:0097435 supramolecular fiber organization; GO:0044708 single-organism behavior; GO:0010975 regulation of neuron projection development; GO:1902903 regulation of supramolecular fiber organization; GO:0000003 reproduction; GO:0050794 regulation of cellular process; GO:0051640 organelle localization; GO:0044707 single-multicellular organism process; GO:0046907 intracellular transport; GO:0002283 neutrophil activation involved in immune response; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0032956 regulation of actin cytoskeleton organization; GO:1901700 response to oxygen-containing compound; GO:0045597 positive regulation of cell differentiation; GO:0048814 regulation of dendrite morphogenesis; GO:0051239 regulation of multicellular organismal process; GO:0035983 response to trichostatin A; GO:1900006 positive regulation of dendrite development; GO:0000910 cytokinesis; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0035902 response to immobilization stress; GO:1902580 single-organism cellular localization; GO:0007275 multicellular organism development; GO:0038093 Fc receptor signaling pathway; GO:0007010 cytoskeleton organization; GO:0050778 positive regulation of immune response; GO:0002253 activation of immune response; GO:0006950 response to stress; GO:0051495 positive regulation of cytoskeleton organization; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0051960 regulation of nervous system development; GO:0060284 regulation of cell development; GO:0002376 immune system process; GO:0071407 cellular response to organic cyclic compound; GO:0032970 regulation of actin filament-based process; GO:0097305 response to alcohol; GO:0010033 response to organic substance; GO:0051656 establishment of organelle localization; GO:0002263 cell activation involved in immune response; GO:0007017 microtubule-based process; GO:0030838 positive regulation of actin filament polymerization; GO:0030031 cell projection assembly; GO:0008064 regulation of actin polymerization or depolymerization; GO:0045055 regulated exocytosis; GO:0061640 cytoskeleton-dependent cytokinesis; GO:0010976 positive regulation of neuron projection development; GO:0098813 nuclear chromosome segregation; GO:0006996 organelle organization; GO:0033206 meiotic cytokinesis; GO:0061024 membrane organization; GO:0030029 actin filament-based process; GO:0001775 cell activation; GO:0000280 nuclear division; GO:0006928 movement of cell or subcellular component; GO:0050769 positive regulation of neurogenesis; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis; GO:0048584 positive regulation of response to stimulus; GO:0006955 immune response; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0006887 exocytosis; GO:0030833 regulation of actin filament polymerization; GO:0034314 Arp2/3 complex-mediated actin nucleation; GO:0045666 positive regulation of neuron differentiation; GO:0032273 positive regulation of protein polymerization; GO:0038094 Fc-gamma receptor signaling pathway; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0006909 phagocytosis; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0050000 chromosome localization; GO:0008356 asymmetric cell division; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0045010 actin nucleation; GO:0032271 regulation of protein polymerization; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0031334 positive regulation of protein complex assembly; GO:0051305 chromosome movement towards spindle pole; GO:0010720 positive regulation of cell development; GO:0070887 cellular response to chemical stimulus; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0002274 myeloid leukocyte activation; GO:0045132 meiotic chromosome segregation; GO:0032502 developmental process; GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis; GO:0060998 regulation of dendritic spine development; GO:0002446 neutrophil mediated immunity; GO:0051962 positive regulation of nervous system development; GO:0048522 positive regulation of cellular process; GO:0051321 meiotic cell cycle; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0002444 myeloid leukocyte mediated immunity; GO:0071417 cellular response to organonitrogen compound; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0043254 regulation of protein complex assembly; GO:0042221 response to chemical; GO:0045664 regulation of neuron differentiation; GO:0010638 positive regulation of organelle organization; GO:0030030 cell projection organization; GO:1901699 cellular response to nitrogen compound; GO:0032940 secretion by cell; GO:0002431 Fc receptor mediated stimulatory signaling pathway; GO:0043299 leukocyte degranulation; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0016043 cellular component organization; GO:1903046 meiotic cell cycle process; GO:0061001 regulation of dendritic spine morphogenesis; GO:0002252 immune effector process; GO:0045471 response to ethanol; GO:0051653 spindle localization; GO:0071310 cellular response to organic substance; GO:0048285 organelle fission; GO:0046677 response to antibiotic; GO:0007015 actin filament organization; GO:0010770 positive regulation of cell morphogenesis involved in differentiation; GO:0044087 regulation of cellular component biogenesis; GO:0031344 regulation of cell projection organization; GO:0035984 cellular response to trichostatin A; GO:0050896 response to stimulus; GO:0030154 cell differentiation; GO:0048013 ephrin receptor signaling pathway; GO:0070925 organelle assembly; GO:0050890 cognition; GO:0002757 immune response-activating signal transduction; GO:0036230 granulocyte activation; GO:0016482 cytosolic transport; GO:0009987 cellular process; GO:0061003 positive regulation of dendritic spine morphogenesis; GO:0045595 regulation of cell differentiation; GO:0003008 system process; GO:0051303 establishment of chromosome localization; GO:0033043 regulation of organelle organization; GO:0006897 endocytosis; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0007611 learning or memory; GO:0051641 cellular localization; GO:0002366 leukocyte activation involved in immune response; GO:0050775 positive regulation of dendrite morphogenesis; GO:0007018 microtubule-based movement; GO:0042119 neutrophil activation; GO:1901701 cellular response to oxygen-containing compound; GO:0071236 cellular response to antibiotic; GO:0044767 single-organism developmental process; GO:0071495 cellular response to endogenous stimulus; GO:0002684 positive regulation of immune system process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0050773 regulation of dendrite development; GO:0090066 regulation of anatomical structure size; GO:0007126 meiotic nuclear division; GO:0008306 associative learning; GO:0022402 cell cycle process; GO:0051128 regulation of cellular component organization; GO:0022604 regulation of cell morphogenesis; GO:0007049 cell cycle; GO:0044089 positive regulation of cellular component biogenesis; GO:0050767 regulation of neurogenesis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0071437 invadopodium; GO:0005737 cytoplasm; GO:0099568 cytoplasmic region; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0005885 Arp2/3 protein complex; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:0014069 postsynaptic density; GO:0030027 lamellipodium; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0031252 cell leading edge; GO:0042995 cell projection; GO:0044430 cytoskeletal part; GO:0070161 anchoring junction; GO:0005576 extracellular region; GO:0042582 azurophil granule; GO:0043231 intracellular membrane-bounded organelle; GO:0098794 postsynapse; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0099572 postsynaptic specialization; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0034774 secretory granule lumen; GO:0005938 cell cortex; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0031982 vesicle; GO:0030863 cortical cytoskeleton; GO:0030864 cortical actin cytoskeleton; GO:0044424 intracellular part; GO:0032279 asymmetric synapse; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0005912 adherens junction; GO:0030141 secretory granule; GO:0030478 actin cap; GO:0098984 neuron to neuron synapse; GO:0044456 synapse part; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0002102 podosome; GO:0005829 cytosol; GO:0015629 actin cytoskeleton; GO:0045202 synapse; GO:0043226 organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0044448 cell cortex part; GO:0044444 cytoplasmic part; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0008092 cytoskeletal protein binding; GO:0005200 structural constituent of cytoskeleton; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0003779 actin binding; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0005198 structural molecule activity; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K17260","ACTR2; actin-related protein 2","hsa04530 Tight junction - Homo sapiens (human); "]
["P61221","ATP-binding cassette sub-family E member 1 OS=Homo sapiens OX=9606 GN=ABCE1","ABCE1",67.314,66.208,18.9,10,14,10,0.952,0.897,0.896,1.133,1.073,1.055,1.188,0.00424,"cytoplasm\r","GO:0050658 RNA transport; GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0006518 peptide metabolic process; GO:0033753 establishment of ribosome localization; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0051169 nuclear transport; GO:0051168 nuclear export; GO:0044764 multi-organism cellular process; GO:0071428 rRNA-containing ribonucleoprotein complex export from nucleus; GO:0044237 cellular metabolic process; GO:0051253 negative regulation of RNA metabolic process; GO:0015031 protein transport; GO:0043241 protein complex disassembly; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0050657 nucleic acid transport; GO:0015931 nucleobase-containing compound transport; GO:0060701 negative regulation of ribonuclease activity; GO:0006413 translational initiation; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0044419 interspecies interaction between organisms; GO:0006412 translation; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0071822 protein complex subunit organization; GO:0080090 regulation of primary metabolic process; GO:0060700 regulation of ribonuclease activity; GO:0043043 peptide biosynthetic process; GO:0044763 single-organism cellular process; GO:0042254 ribosome biogenesis; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0043603 cellular amide metabolic process; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0006611 protein export from nucleus; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051704 multi-organism process; GO:0071166 ribonucleoprotein complex localization; GO:0006810 transport; GO:0006415 translational termination; GO:0000054 ribosomal subunit export from nucleus; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:0060699 regulation of endoribonuclease activity; GO:0050790 regulation of catalytic activity; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0006913 nucleocytoplasmic transport; GO:0044092 negative regulation of molecular function; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0050794 regulation of cellular process; GO:0051640 organelle localization; GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0033750 ribosome localization; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:1901566 organonitrogen compound biosynthetic process; GO:0051346 negative regulation of hydrolase activity; GO:0051236 establishment of RNA localization; GO:0071704 organic substance metabolic process; GO:0032069 regulation of nuclease activity; GO:0016032 viral process; GO:0006886 intracellular protein transport; GO:0043624 cellular protein complex disassembly; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0032074 negative regulation of nuclease activity; GO:0006403 RNA localization; GO:0006405 RNA export from nucleus; GO:0060702 negative regulation of endoribonuclease activity; GO:0006807 nitrogen compound metabolic process; GO:0032984 macromolecular complex disassembly; GO:0071702 organic substance transport; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0044238 primary metabolic process; GO:0051656 establishment of organelle localization; GO:1901576 organic substance biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0009892 negative regulation of metabolic process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0055085 transmembrane transport; GO:0070727 cellular macromolecule localization; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0071426 ribonucleoprotein complex export from nucleus; GO:0022411 cellular component disassembly; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0051179 localization; GO:0071705 nitrogen compound transport; GO:1901564 organonitrogen compound metabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:1901265 nucleoside phosphate binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0004857 enzyme inhibitor activity; GO:0008428 ribonuclease inhibitor activity; GO:0016887 ATPase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0043024 ribosomal small subunit binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0005506 iron ion binding; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0030234 enzyme regulator activity; GO:0046914 transition metal ion binding; GO:0046872 metal ion binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0060698 endoribonuclease inhibitor activity; GO:0043021 ribonucleoprotein complex binding; GO:0036094 small molecule binding; ","K06174",null,null,"IPR003593; IPR003439; IPR017896; IPR027417; IPR034348; IPR007209; ","\"AAA+ ATPase domain; ABC transporter-like; 4Fe-4S ferredoxin-type, iron-sulphur binding domain; P-loop containing nucleoside triphosphate hydrolase; RLI, domain 1; RNase L inhibitor RLI, possible metal-binding domain; \"\r"]
["P61224","Ras-related protein Rap-1b OS=Homo sapiens OX=9606 GN=RAP1B","RAP1B",20.825,52.982,41.8,9,22,4,1.002,1.054,1.036,0.952,0.975,0.963,0.935,0.0147,"cytoplasm\r","GO:0044700 single organism signaling; GO:0060627 regulation of vesicle-mediated transport; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0045321 leukocyte activation; GO:1903306 negative regulation of regulated secretory pathway; GO:0046683 response to organophosphorus; GO:0032879 regulation of localization; GO:0009719 response to endogenous stimulus; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0032387 negative regulation of intracellular transport; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0051051 negative regulation of transport; GO:0042325 regulation of phosphorylation; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0002064 epithelial cell development; GO:0051174 regulation of phosphorus metabolic process; GO:0002443 leukocyte mediated immunity; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:1903531 negative regulation of secretion by cell; GO:0007264 small GTPase mediated signal transduction; GO:0031323 regulation of cellular metabolic process; GO:1901888 regulation of cell junction assembly; GO:0006810 transport; GO:1902803 regulation of synaptic vesicle transport; GO:0010243 response to organonitrogen compound; GO:0051591 response to cAMP; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0010604 positive regulation of macromolecule metabolic process; GO:2000114 regulation of establishment of cell polarity; GO:0030855 epithelial cell differentiation; GO:0050794 regulation of cellular process; GO:0045920 negative regulation of exocytosis; GO:0002283 neutrophil activation involved in immune response; GO:0031399 regulation of protein modification process; GO:1901700 response to oxygen-containing compound; GO:0017157 regulation of exocytosis; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0060341 regulation of cellular localization; GO:0070372 regulation of ERK1 and ERK2 cascade; GO:0023057 negative regulation of signaling; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0010648 negative regulation of cell communication; GO:0014074 response to purine-containing compound; GO:0051588 regulation of neurotransmitter transport; GO:0009966 regulation of signal transduction; GO:0045955 negative regulation of calcium ion-dependent exocytosis; GO:1902531 regulation of intracellular signal transduction; GO:0016192 vesicle-mediated transport; GO:0050804 modulation of synaptic transmission; GO:0002376 immune system process; GO:0071407 cellular response to organic cyclic compound; GO:0008283 cell proliferation; GO:0010033 response to organic substance; GO:0002263 cell activation involved in immune response; GO:0003158 endothelium development; GO:0045055 regulated exocytosis; GO:0051247 positive regulation of protein metabolic process; GO:0001885 endothelial cell development; GO:0031325 positive regulation of cellular metabolic process; GO:0001775 cell activation; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0006955 immune response; GO:0006887 exocytosis; GO:0001505 regulation of neurotransmitter levels; GO:2000301 negative regulation of synaptic vesicle exocytosis; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0051046 regulation of secretion; GO:0044699 single-organism process; GO:0045446 endothelial cell differentiation; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0070887 cellular response to chemical stimulus; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0009888 tissue development; GO:0050805 negative regulation of synaptic transmission; GO:0032878 regulation of establishment or maintenance of cell polarity; GO:0045937 positive regulation of phosphate metabolic process; GO:0002446 neutrophil mediated immunity; GO:0048522 positive regulation of cellular process; GO:0032386 regulation of intracellular transport; GO:1903530 regulation of secretion by cell; GO:0023052 signaling; GO:0046928 regulation of neurotransmitter secretion; GO:0002444 myeloid leukocyte mediated immunity; GO:0071417 cellular response to organonitrogen compound; GO:0051048 negative regulation of secretion; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:1901699 cellular response to nitrogen compound; GO:0032940 secretion by cell; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0043299 leukocyte degranulation; GO:0048856 anatomical structure development; GO:0007265 Ras protein signal transduction; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0044087 regulation of cellular component biogenesis; GO:0050896 response to stimulus; GO:0048468 cell development; GO:2000300 regulation of synaptic vesicle exocytosis; GO:0030154 cell differentiation; GO:1902804 negative regulation of synaptic vesicle transport; GO:0043408 regulation of MAPK cascade; GO:0023056 positive regulation of signaling; GO:0036230 granulocyte activation; GO:0010647 positive regulation of cell communication; GO:0061028 establishment of endothelial barrier; GO:0009987 cellular process; GO:0032486 Rap protein signal transduction; GO:0035556 intracellular signal transduction; GO:0071320 cellular response to cAMP; GO:0051049 regulation of transport; GO:0001932 regulation of protein phosphorylation; GO:0031401 positive regulation of protein modification process; GO:1903305 regulation of regulated secretory pathway; GO:0043312 neutrophil degranulation; GO:0001934 positive regulation of protein phosphorylation; GO:0048518 positive regulation of biological process; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:1901701 cellular response to oxygen-containing compound; GO:0051589 negative regulation of neurotransmitter transport; GO:0044767 single-organism developmental process; GO:0071495 cellular response to endogenous stimulus; GO:0051246 regulation of protein metabolic process; GO:0009967 positive regulation of signal transduction; GO:0051128 regulation of cellular component organization; GO:0043410 positive regulation of MAPK cascade; GO:0070374 positive regulation of ERK1 and ERK2 cascade; GO:0017158 regulation of calcium ion-dependent exocytosis; GO:0046929 negative regulation of neurotransmitter secretion; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005911 cell-cell junction; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005765 lysosomal membrane; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0005811 lipid particle; GO:0043227 membrane-bounded organelle; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0035577 azurophil granule membrane; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0042582 azurophil granule; GO:0098852 lytic vacuole membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0030667 secretory granule membrane; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0019003 GDP binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0003924 GTPase activity; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0017076 purine nucleotide binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0044877 macromolecular complex binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0032561 guanyl ribonucleotide binding; GO:0036094 small molecule binding; GO:0032403 protein complex binding; ","K07836","RAP1B; Ras-related protein Rap-1B","hsa04015 Rap1 signaling pathway - Homo sapiens (human); hsa04934 Cushing's syndrome - Homo sapiens (human); hsa04972 Pancreatic secretion - Homo sapiens (human); hsa04722 Neurotrophin signaling pathway - Homo sapiens (human); hsa04014 Ras signaling pathway - Homo sapiens (human); hsa05211 Renal cell carcinoma - Homo sapiens (human); hsa04024 cAMP signaling pathway - Homo sapiens (human); hsa04611 Platelet activation - Homo sapiens (human); hsa04670 Leukocyte transendothelial migration - Homo sapiens (human); hsa04010 MAPK signaling pathway - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa04720 Long-term potentiation - Homo sapiens (human); hsa04062 Chemokine signaling pathway - Homo sapiens (human); ","IPR005225; IPR027417; ","Small GTP-binding protein domain; P-loop containing nucleoside triphosphate hydrolase; \r"]
["P61289","Proteasome activator complex subunit 3 OS=Homo sapiens OX=9606 GN=PSME3","PSME3",29.506,46.196,29.1,7,11,7,0.709,0.703,0.751,1.244,1.245,1.278,1.742,1.81e-05,"cytoplasm\r","GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0010608 posttranscriptional regulation of gene expression; GO:0051443 positive regulation of ubiquitin-protein transferase activity; GO:0031347 regulation of defense response; GO:0044237 cellular metabolic process; GO:0010564 regulation of cell cycle process; GO:1903364 positive regulation of cellular protein catabolic process; GO:0008152 metabolic process; GO:0044093 positive regulation of molecular function; GO:0090263 positive regulation of canonical Wnt signaling pathway; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0016055 Wnt signaling pathway; GO:0052548 regulation of endopeptidase activity; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0010950 positive regulation of endopeptidase activity; GO:0006521 regulation of cellular amino acid metabolic process; GO:0080090 regulation of primary metabolic process; GO:0010972 negative regulation of G2/M transition of mitotic cell cycle; GO:0044763 single-organism cellular process; GO:0060828 regulation of canonical Wnt signaling pathway; GO:0043086 negative regulation of catalytic activity; GO:0033209 tumor necrosis factor-mediated signaling pathway; GO:0050776 regulation of immune response; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0006810 transport; GO:0000165 MAPK cascade; GO:1901575 organic substance catabolic process; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0007267 cell-cell signaling; GO:0002223 stimulatory C-type lectin receptor signaling pathway; GO:0030163 protein catabolic process; GO:0061136 regulation of proteasomal protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0060071 Wnt signaling pathway, planar cell polarity pathway; GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:0060548 negative regulation of cell death; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0016310 phosphorylation; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0043487 regulation of RNA stability; GO:0000209 protein polyubiquitination; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0051345 positive regulation of hydrolase activity; GO:0009889 regulation of biosynthetic process; GO:0009896 positive regulation of catabolic process; GO:0043620 regulation of DNA-templated transcription in response to stress; GO:0070482 response to oxygen levels; GO:0044248 cellular catabolic process; GO:0042176 regulation of protein catabolic process; GO:0038093 Fc receptor signaling pathway; GO:0050778 positive regulation of immune response; GO:0023014 signal transduction by protein phosphorylation; GO:0006950 response to stress; GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; GO:0016567 protein ubiquitination; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress; GO:1903321 negative regulation of protein modification by small protein conjugation or removal; GO:0031398 positive regulation of protein ubiquitination; GO:0032446 protein modification by small protein conjugation; GO:0031325 positive regulation of cellular metabolic process; GO:0030177 positive regulation of Wnt signaling pathway; GO:1904668 positive regulation of ubiquitin protein ligase activity; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0043412 macromolecule modification; GO:2000045 regulation of G1/S transition of mitotic cell cycle; GO:0070646 protein modification by small protein removal; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0031331 positive regulation of cellular catabolic process; GO:0044699 single-organism process; GO:0031400 negative regulation of protein modification process; GO:0006796 phosphate-containing compound metabolic process; GO:0031396 regulation of protein ubiquitination; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0045930 negative regulation of mitotic cell cycle; GO:0009893 positive regulation of metabolic process; GO:1902806 regulation of cell cycle G1/S phase transition; GO:0006915 apoptotic process; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0034612 response to tumor necrosis factor; GO:0051726 regulation of cell cycle; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0034097 response to cytokine; GO:0031326 regulation of cellular biosynthetic process; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0198738 cell-cell signaling by wnt; GO:0010565 regulation of cellular ketone metabolic process; GO:2001236 regulation of extrinsic apoptotic signaling pathway; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0036211 protein modification process; GO:0090175 regulation of establishment of planar polarity; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0045786 negative regulation of cell cycle; GO:0043069 negative regulation of programmed cell death; GO:0044257 cellular protein catabolic process; GO:1901988 negative regulation of cell cycle phase transition; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0010498 proteasomal protein catabolic process; GO:0071704 organic substance metabolic process; GO:0045862 positive regulation of proteolysis; GO:2000027 regulation of organ morphogenesis; GO:0006468 protein phosphorylation; GO:0043066 negative regulation of apoptotic process; GO:0023056 positive regulation of signaling; GO:0001666 response to hypoxia; GO:0002757 immune response-activating signal transduction; GO:0010647 positive regulation of cell communication; GO:0071453 cellular response to oxygen levels; GO:0019221 cytokine-mediated signaling pathway; GO:0031397 negative regulation of protein ubiquitination; GO:0006355 regulation of transcription, DNA-templated; GO:0035556 intracellular signal transduction; GO:0019941 modification-dependent protein catabolic process; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia; GO:1902749 regulation of cell cycle G2/M phase transition; GO:0043488 regulation of mRNA stability; GO:0043085 positive regulation of catalytic activity; GO:0019882 antigen processing and presentation; GO:0050852 T cell receptor signaling pathway; GO:0008219 cell death; GO:0002684 positive regulation of immune system process; GO:0038095 Fc-epsilon receptor signaling pathway; GO:0051248 negative regulation of protein metabolic process; GO:0022402 cell cycle process; GO:1902750 negative regulation of cell cycle G2/M phase transition; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0042981 regulation of apoptotic process; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0002220 innate immune response activating cell surface receptor signaling pathway; GO:0007166 cell surface receptor signaling pathway; GO:0071345 cellular response to cytokine stimulus; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0051347 positive regulation of transferase activity; GO:1903362 regulation of cellular protein catabolic process; GO:0002758 innate immune response-activating signal transduction; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0031323 regulation of cellular metabolic process; GO:2000058 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0010948 negative regulation of cell cycle process; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0002682 regulation of immune system process; GO:0031145 anaphase-promoting complex-dependent catabolic process; GO:0010952 positive regulation of peptidase activity; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0007346 regulation of mitotic cell cycle; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0043067 regulation of programmed cell death; GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:0051239 regulation of multicellular organismal process; GO:0031349 positive regulation of defense response; GO:1901987 regulation of cell cycle phase transition; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0010389 regulation of G2/M transition of mitotic cell cycle; GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; GO:0009966 regulation of signal transduction; GO:0038061 NIK/NF-kappaB signaling; GO:0071456 cellular response to hypoxia; GO:0002253 activation of immune response; GO:2001237 negative regulation of extrinsic apoptotic signaling pathway; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1904666 regulation of ubiquitin protein ligase activity; GO:0055085 transmembrane transport; GO:0051247 positive regulation of protein metabolic process; GO:0051438 regulation of ubiquitin-protein transferase activity; GO:0030111 regulation of Wnt signaling pathway; GO:0006793 phosphorus metabolic process; GO:0012501 programmed cell death; GO:0036293 response to decreased oxygen levels; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process; GO:0051444 negative regulation of ubiquitin-protein transferase activity; GO:0090090 negative regulation of canonical Wnt signaling pathway; GO:0051234 establishment of localization; GO:0035567 non-canonical Wnt signaling pathway; GO:2001233 regulation of apoptotic signaling pathway; GO:1905330 regulation of morphogenesis of an epithelium; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:1901991 negative regulation of mitotic cell cycle phase transition; GO:0045088 regulation of innate immune response; GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I; GO:0070887 cellular response to chemical stimulus; GO:0050851 antigen receptor-mediated signaling pathway; GO:0010468 regulation of gene expression; GO:0030178 negative regulation of Wnt signaling pathway; GO:0048002 antigen processing and presentation of peptide antigen; GO:0048522 positive regulation of cellular process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0051348 negative regulation of transferase activity; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0019222 regulation of metabolic process; GO:0052547 regulation of peptidase activity; GO:2000026 regulation of multicellular organismal development; GO:0002218 activation of innate immune response; GO:1904667 negative regulation of ubiquitin protein ligase activity; GO:0071356 cellular response to tumor necrosis factor; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0016579 protein deubiquitination; GO:1903322 positive regulation of protein modification by small protein conjugation or removal; GO:0006508 proteolysis; GO:0009987 cellular process; GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:0033238 regulation of cellular amine metabolic process; GO:0043632 modification-dependent macromolecule catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0045089 positive regulation of innate immune response; GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition; GO:0031401 positive regulation of protein modification process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0051246 regulation of protein metabolic process; GO:0009057 macromolecule catabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0009967 positive regulation of signal transduction; GO:0045732 positive regulation of protein catabolic process; GO:0036294 cellular response to decreased oxygen levels; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0000502 proteasome complex; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:1905369 endopeptidase complex; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0022624 proteasome accessory complex; GO:0005622 intracellular; GO:0044464 cell part; GO:1905368 peptidase complex; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0008537 proteasome activator complex; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0002039 p53 binding; GO:0042802 identical protein binding; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0061134 peptidase regulator activity; GO:0016504 peptidase activator activity; GO:0061135 endopeptidase regulator activity; GO:0005515 protein binding; GO:0061133 endopeptidase activator activity; GO:0098772 molecular function regulator; GO:0008047 enzyme activator activity; GO:0097371 MDM2/MDM4 family protein binding; ","K06698","PSME3; proteasome activator subunit 3 (PA28 gamma)","hsa03050 Proteasome - Homo sapiens (human); hsa04612 Antigen processing and presentation - Homo sapiens (human); hsa05160 Hepatitis C - Homo sapiens (human); ","IPR003186; IPR003185; ","\"Proteasome activator pa28, C-terminal domain; Proteasome activator pa28, N-terminal domain; \"\r"]
["P61326","Protein mago nashi homolog OS=Homo sapiens OX=9606 GN=MAGOH","MAGOH",17.163,27.859,33.6,4,5,4,0.951,0.84,0.913,1.114,1.089,1.088,1.217,0.0061,"cytoplasm\r","GO:0050658 RNA transport; GO:0000381 regulation of alternative mRNA splicing, via spliceosome; GO:0010608 posttranscriptional regulation of gene expression; GO:0097659 nucleic acid-templated transcription; GO:0009058 biosynthetic process; GO:0051168 nuclear export; GO:0051169 nuclear transport; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006353 DNA-templated transcription, termination; GO:0071427 mRNA-containing ribonucleoprotein complex export from nucleus; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0050657 nucleic acid transport; GO:0015931 nucleobase-containing compound transport; GO:1901361 organic cyclic compound catabolic process; GO:0043170 macromolecule metabolic process; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0048024 regulation of mRNA splicing, via spliceosome; GO:0006396 RNA processing; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0050684 regulation of mRNA processing; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0006611 protein export from nucleus; GO:0071166 ribonucleoprotein complex localization; GO:0006401 RNA catabolic process; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006913 nucleocytoplasmic transport; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0031123 RNA 3'-end processing; GO:0046907 intracellular transport; GO:0006725 cellular aromatic compound metabolic process; GO:0031124 mRNA 3'-end processing; GO:0060255 regulation of macromolecule metabolic process; GO:0051028 mRNA transport; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0048519 negative regulation of biological process; GO:0051236 establishment of RNA localization; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0006886 intracellular protein transport; GO:0044248 cellular catabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0009059 macromolecule biosynthetic process; GO:0034613 cellular protein localization; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0006406 mRNA export from nucleus; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0006369 termination of RNA polymerase II transcription; GO:0006403 RNA localization; GO:0006405 RNA export from nucleus; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0034248 regulation of cellular amide metabolic process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0043484 regulation of RNA splicing; GO:0070727 cellular macromolecule localization; GO:1903311 regulation of mRNA metabolic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0071426 ribonucleoprotein complex export from nucleus; GO:0051246 regulation of protein metabolic process; GO:0006417 regulation of translation; GO:0009057 macromolecule catabolic process; GO:0006366 transcription from RNA polymerase II promoter; GO:0010467 gene expression; GO:0051179 localization; GO:0009056 catabolic process; GO:0071705 nitrogen compound transport; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005681 spliceosomal complex; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0005622 intracellular; GO:0044464 cell part; GO:0071013 catalytic step 2 spliceosome; GO:1990904 ribonucleoprotein complex; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0030529 intracellular ribonucleoprotein complex; GO:0035145 exon-exon junction complex; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005515 protein binding; GO:0005488 binding; GO:0003676 nucleic acid binding; ","K12877","MAGOH; protein mago nashi","hsa03040 Spliceosome - Homo sapiens (human); hsa03015 mRNA surveillance pathway - Homo sapiens (human); hsa03013 RNA transport - Homo sapiens (human); "]
["P61457","Pterin-4-alpha-carbinolamine dehydratase OS=Homo sapiens OX=9606 GN=PCBD1","PCBD1",11.999,7.7591,23.1,2,2,2,0.959,1.087,0.971,0.898,1.051,1.041,0.991,0.885,"extracellular\r","GO:0051188 cofactor biosynthetic process; GO:0044085 cellular component biogenesis; GO:1902222 erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process; GO:0042559 pteridine-containing compound biosynthetic process; GO:1901606 alpha-amino acid catabolic process; GO:0097659 nucleic acid-templated transcription; GO:0009891 positive regulation of biosynthetic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0006559 L-phenylalanine catabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0051262 protein tetramerization; GO:0022607 cellular component assembly; GO:0009893 positive regulation of metabolic process; GO:0065003 macromolecular complex assembly; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:1901361 organic cyclic compound catabolic process; GO:0009108 coenzyme biosynthetic process; GO:0043170 macromolecule metabolic process; GO:0009072 aromatic amino acid family metabolic process; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0071822 protein complex subunit organization; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044763 single-organism cellular process; GO:0051098 regulation of binding; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0006732 coenzyme metabolic process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0051186 cofactor metabolic process; GO:0016070 RNA metabolic process; GO:0051291 protein heterooligomerization; GO:0046395 carboxylic acid catabolic process; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0065009 regulation of molecular function; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0009063 cellular amino acid catabolic process; GO:0070271 protein complex biogenesis; GO:0006082 organic acid metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0043436 oxoacid metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0051260 protein homooligomerization; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0051259 protein oligomerization; GO:0071704 organic substance metabolic process; GO:0043393 regulation of protein binding; GO:0051289 protein homotetramerization; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006729 tetrahydrobiopterin biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0051171 regulation of nitrogen compound metabolic process; GO:0044248 cellular catabolic process; GO:0046146 tetrahydrobiopterin metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0009059 macromolecule biosynthetic process; GO:1902221 erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0051254 positive regulation of RNA metabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0009074 aromatic amino acid family catabolic process; GO:0044712 single-organism catabolic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044282 small molecule catabolic process; GO:0043496 regulation of protein homodimerization activity; GO:0044238 primary metabolic process; GO:1901605 alpha-amino acid metabolic process; GO:1901576 organic substance biosynthetic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0042558 pteridine-containing compound metabolic process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0006558 L-phenylalanine metabolic process; GO:1901565 organonitrogen compound catabolic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0031325 positive regulation of cellular metabolic process; GO:0016054 organic acid catabolic process; GO:0019752 carboxylic acid metabolic process; GO:0010467 gene expression; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0008124 4-alpha-hydroxytetrahydrobiopterin dehydratase activity; GO:0016829 lyase activity; GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; GO:0004505 phenylalanine 4-monooxygenase activity; GO:0005515 protein binding; GO:0016836 hydro-lyase activity; GO:0003712 transcription cofactor activity; GO:0016835 carbon-oxygen lyase activity; GO:0016491 oxidoreductase activity; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen; GO:0005488 binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0003713 transcription coactivator activity; GO:0000988 transcription factor activity, protein binding; GO:0004497 monooxygenase activity; ","K01724","PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]","hsa00790 Folate biosynthesis - Homo sapiens (human); "]
["P61513","60S ribosomal protein L37a OS=Homo sapiens OX=9606 GN=RPL37A","RPL37A",10.275,5.0019,21.7,2,2,2,0.836,0.818,0.843,1.118,1.129,1.239,1.396,0.000604,"extracellular\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0072594 establishment of protein localization to organelle; GO:0006518 peptide metabolic process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0051649 establishment of localization in cell; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0070972 protein localization to endoplasmic reticulum; GO:0006364 rRNA processing; GO:0006413 translational initiation; GO:1901361 organic cyclic compound catabolic process; GO:0033365 protein localization to organelle; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0006412 translation; GO:0016072 rRNA metabolic process; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0072657 protein localization to membrane; GO:0043043 peptide biosynthetic process; GO:0042254 ribosome biogenesis; GO:1901360 organic cyclic compound metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032774 RNA biosynthetic process; GO:0045047 protein targeting to ER; GO:0043603 cellular amide metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0006401 RNA catabolic process; GO:0016070 RNA metabolic process; GO:0019439 aromatic compound catabolic process; GO:1901575 organic substance catabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0019083 viral transcription; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0046907 intracellular transport; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0044267 cellular protein metabolic process; GO:0006613 cotranslational protein targeting to membrane; GO:0048519 negative regulation of biological process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0016032 viral process; GO:0019080 viral gene expression; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0006886 intracellular protein transport; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0034613 cellular protein localization; GO:0009059 macromolecule biosynthetic process; GO:0090150 establishment of protein localization to membrane; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0051179 localization; GO:0009056 catabolic process; GO:0034660 ncRNA metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0044421 extracellular region part; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0044391 ribosomal subunit; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030055 cell-substrate junction; GO:0044445 cytosolic part; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0022626 cytosolic ribosome; GO:0043229 intracellular organelle; GO:0005840 ribosome; GO:0043232 intracellular non-membrane-bounded organelle; GO:0022625 cytosolic large ribosomal subunit; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0015934 large ribosomal subunit; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0043167 ion binding; GO:0003676 nucleic acid binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0005198 structural molecule activity; GO:0003735 structural constituent of ribosome; ","K02921","RP-L37Ae; large subunit ribosomal protein L37Ae","hsa03010 Ribosome - Homo sapiens (human); ","IPR011332; IPR011331; ","Zinc-binding ribosomal protein; Ribosomal protein L37ae/L37e; \r"]
["P61619","Protein transport protein Sec61 subunit alpha isoform 1 OS=Homo sapiens OX=9606 GN=SEC61A1","SEC61A1",52.264,16.032,13.2,6,11,6,1.037,1.09,0.898,0.984,1.031,0.973,0.988,0.886,"plasma membrane\r","GO:0044700 single organism signaling; GO:0010256 endomembrane system organization; GO:0072594 establishment of protein localization to organelle; GO:0044699 single-organism process; GO:0048793 pronephros development; GO:0030968 endoplasmic reticulum unfolded protein response; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0007165 signal transduction; GO:0035966 response to topologically incorrect protein; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0070972 protein localization to endoplasmic reticulum; GO:0033365 protein localization to organelle; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0072657 protein localization to membrane; GO:0034097 response to cytokine; GO:0016049 cell growth; GO:0044763 single-organism cellular process; GO:0045047 protein targeting to ER; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:0001655 urogenital system development; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0006952 defense response; GO:0006620 posttranslational protein targeting to membrane; GO:0048856 anatomical structure development; GO:0007029 endoplasmic reticulum organization; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0033554 cellular response to stress; GO:0044707 single-multicellular organism process; GO:0035967 cellular response to topologically incorrect protein; GO:0034976 response to endoplasmic reticulum stress; GO:0071310 cellular response to organic substance; GO:0036498 IRE1-mediated unfolded protein response; GO:0072001 renal system development; GO:0006613 cotranslational protein targeting to membrane; GO:0050896 response to stimulus; GO:0045087 innate immune response; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0006886 intracellular protein transport; GO:0039019 pronephric nephron development; GO:0072006 nephron development; GO:0007275 multicellular organism development; GO:0034613 cellular protein localization; GO:0090150 establishment of protein localization to membrane; GO:0009987 cellular process; GO:0006986 response to unfolded protein; GO:0001822 kidney development; GO:0034620 cellular response to unfolded protein; GO:0006950 response to stress; GO:0048731 system development; GO:0071702 organic substance transport; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0034341 response to interferon-gamma; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0051179 localization; GO:0006955 immune response; GO:0040007 growth; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0005791 rough endoplasmic reticulum; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044432 endoplasmic reticulum part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0031227 intrinsic component of endoplasmic reticulum membrane; GO:0030176 integral component of endoplasmic reticulum membrane; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; ","GO:0043022 ribosome binding; GO:0005515 protein binding; GO:0043021 ribonucleoprotein complex binding; GO:0005488 binding; GO:0044877 macromolecular complex binding; ","K10956","SEC61A; protein transport protein SEC61 subunit alpha","hsa03060 Protein export - Homo sapiens (human); hsa05110 Vibrio cholerae infection - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); ","IPR023201; IPR019561; ","\"SecY subunit domain; Translocon Sec61/SecY, plug domain; \"\r"]
["P61626","Lysozyme C OS=Homo sapiens OX=9606 GN=LYZ","LYZ",16.537,15.13,27.7,4,8,4,0.7,0.691,0.72,1.295,1.332,1.29,1.856,1.27e-06,"extracellular\r","GO:0044707 single-multicellular organism process; GO:0065008 regulation of biological quality; GO:0019835 cytolysis; GO:0045321 leukocyte activation; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0044267 cellular protein metabolic process; GO:0098542 defense response to other organism; GO:0044699 single-organism process; GO:0006959 humoral immune response; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0051707 response to other organism; GO:0048871 multicellular organismal homeostasis; GO:0060249 anatomical structure homeostasis; GO:0051234 establishment of localization; GO:0071704 organic substance metabolic process; GO:0009607 response to biotic stimulus; GO:0042592 homeostatic process; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0036230 granulocyte activation; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0009987 cellular process; GO:0009617 response to bacterium; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0002443 leukocyte mediated immunity; GO:0006950 response to stress; GO:0042742 defense response to bacterium; GO:0019730 antimicrobial humoral response; GO:0002446 neutrophil mediated immunity; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0002376 immune system process; GO:0043312 neutrophil degranulation; GO:0044238 primary metabolic process; GO:0032501 multicellular organismal process; GO:0002263 cell activation involved in immune response; GO:0002444 myeloid leukocyte mediated immunity; GO:0051704 multi-organism process; GO:0006810 transport; GO:0002366 leukocyte activation involved in immune response; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:0001895 retina homeostasis; GO:0032940 secretion by cell; GO:0006954 inflammatory response; GO:0001894 tissue homeostasis; GO:0044260 cellular macromolecule metabolic process; GO:0001775 cell activation; GO:0043299 leukocyte degranulation; GO:0006952 defense response; GO:0051179 localization; GO:0006955 immune response; GO:0065007 biological regulation; GO:0006887 exocytosis; ","GO:0034774 secretory granule lumen; GO:1904724 tertiary granule lumen; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0070820 tertiary granule; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0042582 azurophil granule; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0035580 specific granule lumen; GO:0005766 primary lysosome; GO:0042581 specific granule; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0003796 lysozyme activity; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016798 hydrolase activity, acting on glycosyl bonds; GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0061783 peptidoglycan muralytic activity; ","K13915","LYZ; lysozyme C [EC:3.2.1.17]","hsa04970 Salivary secretion - Homo sapiens (human); ","IPR023346; ","Lysozyme-like domain; \r"]
["P61916","NPC intracellular cholesterol transporter 2 OS=Homo sapiens OX=9606 GN=NPC2","NPC2",16.57,27.325,36.4,4,12,4,0.973,1.025,1.029,0.997,1.016,0.989,0.992,0.705,"extracellular\r","GO:0065008 regulation of biological quality; GO:0015850 organic hydroxy compound transport; GO:0045321 leukocyte activation; GO:0033344 cholesterol efflux; GO:0030301 cholesterol transport; GO:0006066 alcohol metabolic process; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0019216 regulation of lipid metabolic process; GO:0009607 response to biotic stimulus; GO:0051234 establishment of localization; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0032365 intracellular lipid transport; GO:0051649 establishment of localization in cell; GO:0044419 interspecies interaction between organisms; GO:0033036 macromolecule localization; GO:0055088 lipid homeostasis; GO:0002274 myeloid leukocyte activation; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0006629 lipid metabolic process; GO:0002443 leukocyte mediated immunity; GO:0006869 lipid transport; GO:0080090 regulation of primary metabolic process; GO:0002446 neutrophil mediated immunity; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0008202 steroid metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0031323 regulation of cellular metabolic process; GO:0051704 multi-organism process; GO:1902582 single-organism intracellular transport; GO:0002444 myeloid leukocyte mediated immunity; GO:0006810 transport; GO:0015748 organophosphate ester transport; GO:0050789 regulation of biological process; GO:0019747 regulation of isoprenoid metabolic process; GO:0032940 secretion by cell; GO:0044710 single-organism metabolic process; GO:0032367 intracellular cholesterol transport; GO:0019222 regulation of metabolic process; GO:0043299 leukocyte degranulation; GO:0009615 response to virus; GO:0050794 regulation of cellular process; GO:0015918 sterol transport; GO:0046907 intracellular transport; GO:0002283 neutrophil activation involved in immune response; GO:1901615 organic hydroxy compound metabolic process; GO:1902652 secondary alcohol metabolic process; GO:0002252 immune effector process; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0016125 sterol metabolic process; GO:0032366 intracellular sterol transport; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0016032 viral process; GO:1901264 carbohydrate derivative transport; GO:1902580 single-organism cellular localization; GO:0006898 receptor-mediated endocytosis; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0008203 cholesterol metabolic process; GO:0046836 glycolipid transport; GO:0016192 vesicle-mediated transport; GO:0071702 organic substance transport; GO:0010876 lipid localization; GO:0002376 immune system process; GO:0015914 phospholipid transport; GO:0006897 endocytosis; GO:0044238 primary metabolic process; GO:0043312 neutrophil degranulation; GO:0042632 cholesterol homeostasis; GO:0002263 cell activation involved in immune response; GO:0051641 cellular localization; GO:0006820 anion transport; GO:0002366 leukocyte activation involved in immune response; GO:0015711 organic anion transport; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0006811 ion transport; GO:0055092 sterol homeostasis; GO:0001775 cell activation; GO:0051179 localization; GO:0006955 immune response; GO:0065007 biological regulation; GO:0006887 exocytosis; ","GO:0034774 secretory granule lumen; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0043202 lysosomal lumen; GO:0005576 extracellular region; GO:0042582 azurophil granule; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:0015485 cholesterol binding; GO:0032934 sterol binding; GO:0005488 binding; GO:0043178 alcohol binding; GO:0008289 lipid binding; GO:0005515 protein binding; GO:0019899 enzyme binding; GO:0005496 steroid binding; GO:0036094 small molecule binding; ","K13443","NPC2; Niemann-Pick C2 protein","hsa04142 Lysosome - Homo sapiens (human); hsa04979 Cholesterol metabolism - Homo sapiens (human); ","IPR033916; IPR014756; IPR003172; ","\"ML domain, Npc2 like; Immunoglobulin E-set; MD-2-related lipid-recognition domain; \"\r"]
["P61923","Coatomer subunit zeta-1 OS=Homo sapiens OX=9606 GN=COPZ1","COPZ1",20.198,40.608,22.6,3,4,3,0.976,0.955,0.875,1.076,1.001,1.092,1.129,0.0465,"cytoskeleton\r","GO:0046907 intracellular transport; GO:0006891 intra-Golgi vesicle-mediated transport; GO:0016192 vesicle-mediated transport; GO:0048193 Golgi vesicle transport; GO:0071702 organic substance transport; GO:1901998 toxin transport; GO:0015031 protein transport; GO:0051641 cellular localization; GO:0051234 establishment of localization; GO:0006810 transport; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0051649 establishment of localization in cell; GO:0006890 retrograde vesicle-mediated transport, Golgi to ER; GO:0006886 intracellular protein transport; GO:0051179 localization; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0034613 cellular protein localization; GO:0006888 ER to Golgi vesicle-mediated transport; ","GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0098796 membrane protein complex; GO:0030137 COPI-coated vesicle; GO:0030660 Golgi-associated vesicle membrane; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0030120 vesicle coat; GO:0030663 COPI-coated vesicle membrane; GO:0005623 cell; GO:0030662 coated vesicle membrane; GO:0044422 organelle part; GO:0030126 COPI vesicle coat; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0044431 Golgi apparatus part; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0048475 coated membrane; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0005829 cytosol; GO:0030135 coated vesicle; GO:0005798 Golgi-associated vesicle; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044432 endoplasmic reticulum part; GO:0030117 membrane coat; GO:0030133 transport vesicle; GO:0043234 protein complex; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ",null,"K20472",null,null,"IPR022775; IPR011012; ","\"AP complex, mu/sigma subunit; Longin-like domain; \"\r"]
["P61962","DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7","DCAF7",38.926,18.768,10.8,3,3,3,0.931,1.006,0.948,0.931,1.083,1.101,1.08,0.27,"cytoplasm\r","GO:0032502 developmental process; GO:0044707 single-multicellular organism process; GO:0016567 protein ubiquitination; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0070647 protein modification by small protein conjugation or removal; GO:0044238 primary metabolic process; GO:0032501 multicellular organismal process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0032446 protein modification by small protein conjugation; GO:0044767 single-organism developmental process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0007275 multicellular organism development; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:0048856 anatomical structure development; GO:0009987 cellular process; ","GO:0043229 intracellular organelle; GO:0080008 Cul4-RING E3 ubiquitin ligase complex; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031461 cullin-RING ubiquitin ligase complex; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:1990234 transferase complex; GO:0016604 nuclear body; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0016363 nuclear matrix; GO:0034399 nuclear periphery; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0000151 ubiquitin ligase complex; GO:0044451 nucleoplasm part; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0005488 binding; ","K11805",null,null,"IPR017986; IPR015943; ","WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain; \r"]
["P61970","Nuclear transport factor 2 OS=Homo sapiens OX=9606 GN=NUTF2","NUTF2",14.478,67.533,51.2,4,15,4,0.982,0.986,1.008,1.05,1.059,0.997,1.044,0.107,"cyto_nucl\r","GO:0050658 RNA transport; GO:0010256 endomembrane system organization; GO:0072594 establishment of protein localization to organelle; GO:1903533 regulation of protein targeting; GO:0017038 protein import; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0051168 nuclear export; GO:0090204 protein localization to nuclear pore; GO:0051169 nuclear transport; GO:0001818 negative regulation of cytokine production; GO:0010574 regulation of vascular endothelial growth factor production; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0042306 regulation of protein import into nucleus; GO:0051649 establishment of localization in cell; GO:0050657 nucleic acid transport; GO:0032879 regulation of localization; GO:0015931 nucleobase-containing compound transport; GO:0046824 positive regulation of nucleocytoplasmic transport; GO:0033365 protein localization to organelle; GO:0006606 protein import into nucleus; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:1904046 negative regulation of vascular endothelial growth factor production; GO:0044765 single-organism transport; GO:0044763 single-organism cellular process; GO:0071806 protein transmembrane transport; GO:0032386 regulation of intracellular transport; GO:0006611 protein export from nucleus; GO:1902582 single-organism intracellular transport; GO:0051050 positive regulation of transport; GO:0006810 transport; GO:0050789 regulation of biological process; GO:1900180 regulation of protein localization to nucleus; GO:0051223 regulation of protein transport; GO:0006913 nucleocytoplasmic transport; GO:0051222 positive regulation of protein transport; GO:0042307 positive regulation of protein import into nucleus; GO:0046907 intracellular transport; GO:0006997 nucleus organization; GO:0016043 cellular component organization; GO:0090316 positive regulation of intracellular protein transport; GO:0000060 protein import into nucleus, translocation; GO:1903829 positive regulation of cellular protein localization; GO:1902593 single-organism nuclear import; GO:0051028 mRNA transport; GO:1904589 regulation of protein import; GO:0048519 negative regulation of biological process; GO:0070201 regulation of establishment of protein localization; GO:0051236 establishment of RNA localization; GO:0051239 regulation of multicellular organismal process; GO:0060341 regulation of cellular localization; GO:0006998 nuclear envelope organization; GO:1902578 single-organism localization; GO:0006886 intracellular protein transport; GO:0044744 protein targeting to nucleus; GO:1902580 single-organism cellular localization; GO:0032880 regulation of protein localization; GO:0034613 cellular protein localization; GO:0033157 regulation of intracellular protein transport; GO:0009987 cellular process; GO:0051049 regulation of transport; GO:0032388 positive regulation of intracellular transport; GO:0006403 RNA localization; GO:0044802 single-organism membrane organization; GO:0071702 organic substance transport; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:1900182 positive regulation of protein localization to nucleus; GO:0055085 transmembrane transport; GO:0070727 cellular macromolecule localization; GO:0046822 regulation of nucleocytoplasmic transport; GO:1904951 positive regulation of establishment of protein localization; GO:0051170 nuclear import; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0001817 regulation of cytokine production; GO:0051179 localization; GO:0034504 protein localization to nucleus; GO:1903827 regulation of cellular protein localization; GO:1904591 positive regulation of protein import; GO:0071705 nitrogen compound transport; GO:0090435 protein localization to nuclear envelope; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0019867 outer membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0031090 organelle membrane; GO:0044613 nuclear pore central transport channel; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005640 nuclear outer membrane; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0031965 nuclear membrane; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0098805 whole membrane; GO:0019866 organelle inner membrane; GO:1903561 extracellular vesicle; GO:0031968 organelle outer membrane; GO:0043227 membrane-bounded organelle; GO:0005637 nuclear inner membrane; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005643 nuclear pore; GO:0098588 bounding membrane of organelle; GO:0005635 nuclear envelope; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0031975 envelope; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0031267 small GTPase binding; GO:0008565 protein transporter activity; GO:0017016 Ras GTPase binding; GO:0022884 macromolecule transmembrane transporter activity; GO:0005488 binding; GO:0022892 substrate-specific transporter activity; GO:0008320 protein transmembrane transporter activity; GO:0008536 Ran GTPase binding; GO:0005515 protein binding; GO:0051020 GTPase binding; GO:0019899 enzyme binding; GO:0022891 substrate-specific transmembrane transporter activity; GO:0022857 transmembrane transporter activity; GO:0005215 transporter activity; ",{"$nulls":3},"IPR002075; IPR018222; IPR032710; ","\"Nuclear transport factor 2; Nuclear transport factor 2, eukaryote; NTF2-like domain; \"\r"]
["P62068","Ubiquitin carboxyl-terminal hydrolase 46 OS=Homo sapiens OX=9606 GN=USP46","USP46",42.442,1.7724,2.2,1,1,1,0.979,1.069,0.956,0.995,0.923,1.087,1,0.99,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0070646 protein modification by small protein removal; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0045471 response to ethanol; GO:0023051 regulation of signaling; GO:1901700 response to oxygen-containing compound; GO:0044267 cellular protein metabolic process; GO:0060004 reflex; GO:0044699 single-organism process; GO:0033555 multicellular organismal response to stress; GO:0050896 response to stimulus; GO:0016579 protein deubiquitination; GO:0044237 cellular metabolic process; GO:0032228 regulation of synaptic transmission, GABAergic; GO:0071704 organic substance metabolic process; GO:0007610 behavior; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0010646 regulation of cell communication; GO:0001662 behavioral fear response; GO:0002209 behavioral defense response; GO:0044248 cellular catabolic process; GO:0006508 proteolysis; GO:0007631 feeding behavior; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0030534 adult behavior; GO:0009987 cellular process; GO:0043632 modification-dependent macromolecule catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0006950 response to stress; GO:0019941 modification-dependent protein catabolic process; GO:0050804 modulation of synaptic transmission; GO:0097305 response to alcohol; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0010033 response to organic substance; GO:0070647 protein modification by small protein conjugation or removal; GO:0044238 primary metabolic process; GO:0032501 multicellular organismal process; GO:0048149 behavioral response to ethanol; GO:1901575 organic substance catabolic process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0030163 protein catabolic process; GO:0009057 macromolecule catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0008343 adult feeding behavior; GO:0006952 defense response; GO:0060013 righting reflex; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:0009056 catabolic process; GO:0044708 single-organism behavior; GO:0042596 fear response; GO:0065007 biological regulation; ",null,"GO:0004843 thiol-dependent ubiquitin-specific protease activity; GO:0008233 peptidase activity; GO:0036459 thiol-dependent ubiquitinyl hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0101005 ubiquitinyl hydrolase activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0019783 ubiquitin-like protein-specific protease activity; GO:0005515 protein binding; GO:0008234 cysteine-type peptidase activity; GO:0016787 hydrolase activity; ","K11842",null,null,"IPR028889; IPR001394; ","\"Ubiquitin specific protease domain; Peptidase C19, ubiquitin carboxyl-terminal hydrolase; \"\r"]
["P62072","Mitochondrial import inner membrane translocase subunit Tim10 OS=Homo sapiens OX=9606 GN=TIMM10","TIMM10",10.333,14.291,22.2,2,3,2,0.926,0.958,0.88,1.125,1.175,0.939,1.172,0.101,"extracellular\r","GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0072594 establishment of protein localization to organelle; GO:0007006 mitochondrial membrane organization; GO:0017038 protein import; GO:0006839 mitochondrial transport; GO:0044699 single-organism process; GO:0050877 neurological system process; GO:0015031 protein transport; GO:0045039 protein import into mitochondrial inner membrane; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0051649 establishment of localization in cell; GO:1902578 single-organism localization; GO:0090151 establishment of protein localization to mitochondrial membrane; GO:0007005 mitochondrion organization; GO:1990542 mitochondrial transmembrane transport; GO:0006886 intracellular protein transport; GO:0065002 intracellular protein transmembrane transport; GO:0006626 protein targeting to mitochondrion; GO:1902580 single-organism cellular localization; GO:0033365 protein localization to organelle; GO:0044743 protein transmembrane import into intracellular organelle; GO:0034613 cellular protein localization; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0009987 cellular process; GO:0090150 establishment of protein localization to membrane; GO:0072321 chaperone-mediated protein transport; GO:0044765 single-organism transport; GO:0007600 sensory perception; GO:0003008 system process; GO:0072657 protein localization to membrane; GO:0044763 single-organism cellular process; GO:0071806 protein transmembrane transport; GO:0044802 single-organism membrane organization; GO:0071702 organic substance transport; GO:0070585 protein localization to mitochondrion; GO:0032501 multicellular organismal process; GO:1902582 single-organism intracellular transport; GO:0051641 cellular localization; GO:0007007 inner mitochondrial membrane organization; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:1902589 single-organism organelle organization; GO:0055085 transmembrane transport; GO:0070727 cellular macromolecule localization; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0007605 sensory perception of sound; GO:0051179 localization; GO:0072655 establishment of protein localization to mitochondrion; GO:0050954 sensory perception of mechanical stimulus; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0098798 mitochondrial protein complex; GO:0005744 mitochondrial inner membrane presequence translocase complex; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0044422 organelle part; GO:0042719 mitochondrial intermembrane space protein transporter complex; GO:0031974 membrane-enclosed lumen; GO:0005740 mitochondrial envelope; GO:0031970 organelle envelope lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0019866 organelle inner membrane; GO:1990351 transporter complex; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005758 mitochondrial intermembrane space; GO:0031975 envelope; GO:0043234 protein complex; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0042802 identical protein binding; GO:0008565 protein transporter activity; GO:0046914 transition metal ion binding; GO:0051087 chaperone binding; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0046983 protein dimerization activity; GO:0043167 ion binding; GO:0043169 cation binding; GO:0022892 substrate-specific transporter activity; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0008270 zinc ion binding; GO:0005215 transporter activity; ","K17778",null,null,"IPR004217; ","Tim10/DDP family zinc finger; \r"]
["P62140","Serine/threonine-protein phosphatase PP1-beta catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CB","PPP1CB",37.186,7.3849,30,8,17,2,0.983,0.93,1.057,1.003,0.997,1.034,1.022,0.591,"cytoplasm\r","GO:0043467 regulation of generation of precursor metabolites and energy; GO:0005981 regulation of glycogen catabolic process; GO:0032885 regulation of polysaccharide biosynthetic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0044264 cellular polysaccharide metabolic process; GO:0043153 entrainment of circadian clock by photoperiod; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0044262 cellular carbohydrate metabolic process; GO:0042752 regulation of circadian rhythm; GO:0044770 cell cycle phase transition; GO:0009314 response to radiation; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0000278 mitotic cell cycle; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0006073 cellular glucan metabolic process; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0010675 regulation of cellular carbohydrate metabolic process; GO:0055114 oxidation-reduction process; GO:0009894 regulation of catabolic process; GO:0043470 regulation of carbohydrate catabolic process; GO:0044763 single-organism cellular process; GO:0005975 carbohydrate metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0007623 circadian rhythm; GO:0044723 single-organism carbohydrate metabolic process; GO:0050789 regulation of biological process; GO:0009649 entrainment of circadian clock; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006464 cellular protein modification process; GO:0051301 cell division; GO:0036211 protein modification process; GO:0000086 G2/M transition of mitotic cell cycle; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0043255 regulation of carbohydrate biosynthetic process; GO:0044707 single-multicellular organism process; GO:0060255 regulation of macromolecule metabolic process; GO:0009628 response to abiotic stimulus; GO:0044042 glucan metabolic process; GO:0044267 cellular protein metabolic process; GO:0009648 photoperiodism; GO:0006112 energy reserve metabolic process; GO:0010906 regulation of glucose metabolic process; GO:0050896 response to stimulus; GO:1903047 mitotic cell cycle process; GO:0071704 organic substance metabolic process; GO:0010962 regulation of glucan biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0005976 polysaccharide metabolic process; GO:0009987 cellular process; GO:0044772 mitotic cell cycle phase transition; GO:0043471 regulation of cellular carbohydrate catabolic process; GO:0009416 response to light stimulus; GO:0005977 glycogen metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0006109 regulation of carbohydrate metabolic process; GO:0032881 regulation of polysaccharide metabolic process; GO:0044238 primary metabolic process; GO:0006470 protein dephosphorylation; GO:0032922 circadian regulation of gene expression; GO:0016311 dephosphorylation; GO:0030155 regulation of cell adhesion; GO:0006793 phosphorus metabolic process; GO:0070873 regulation of glycogen metabolic process; GO:0048511 rhythmic process; GO:0005979 regulation of glycogen biosynthetic process; GO:0022402 cell cycle process; GO:0044839 cell cycle G2/M phase transition; GO:0043412 macromolecule modification; GO:0007049 cell cycle; GO:0065007 biological regulation; ","GO:0044421 extracellular region part; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0008287 protein serine/threonine phosphatase complex; GO:0044424 intracellular part; GO:0072357 PTW/PP1 phosphatase complex; GO:0005623 cell; GO:0000164 protein phosphatase type 1 complex; GO:1903293 phosphatase complex; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:1902494 catalytic complex; GO:0005925 focal adhesion; GO:0070013 intracellular organelle lumen; GO:0042587 glycogen granule; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0004722 protein serine/threonine phosphatase activity; GO:0016791 phosphatase activity; GO:0043167 ion binding; GO:0019901 protein kinase binding; GO:0017018 myosin phosphatase activity; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0004721 phosphoprotein phosphatase activity; GO:0019900 kinase binding; GO:0042578 phosphoric ester hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0050115 myosin-light-chain-phosphatase activity; GO:0019899 enzyme binding; ","K06269","PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]","hsa04921 Oxytocin signaling pathway - Homo sapiens (human); hsa04728 Dopaminergic synapse - Homo sapiens (human); hsa04218 Cellular senescence - Homo sapiens (human); hsa05168 Herpes simplex infection - Homo sapiens (human); hsa05031 Amphetamine addiction - Homo sapiens (human); hsa04910 Insulin signaling pathway - Homo sapiens (human); hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human); hsa04270 Vascular smooth muscle contraction - Homo sapiens (human); hsa04024 cAMP signaling pathway - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa03015 mRNA surveillance pathway - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa04750 Inflammatory mediator regulation of TRP channels - Homo sapiens (human); hsa04931 Insulin resistance - Homo sapiens (human); hsa04114 Oocyte meiosis - Homo sapiens (human); hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa04390 Hippo signaling pathway - Homo sapiens (human); hsa04611 Platelet activation - Homo sapiens (human); hsa05034 Alcoholism - Homo sapiens (human); hsa04720 Long-term potentiation - Homo sapiens (human); ","IPR029052; IPR004843; IPR031675; IPR006186; ","\"Metallo-dependent phosphatase-like; Calcineurin-like phosphoesterase domain, ApaH type; Serine-threonine protein phosphatase, N-terminal; Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase; \"\r"]
["P62191","26S proteasome regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMC1","PSMC1",49.184,90.007,34.5,17,24,17,0.915,0.94,0.953,1.059,1.046,1.081,1.135,0.00118,"cyto_nucl\r","GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0010608 posttranscriptional regulation of gene expression; GO:0051443 positive regulation of ubiquitin-protein transferase activity; GO:0009891 positive regulation of biosynthetic process; GO:0031347 regulation of defense response; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:1903364 positive regulation of cellular protein catabolic process; GO:0008152 metabolic process; GO:0044093 positive regulation of molecular function; GO:0090263 positive regulation of canonical Wnt signaling pathway; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0016055 Wnt signaling pathway; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0006521 regulation of cellular amino acid metabolic process; GO:0080090 regulation of primary metabolic process; GO:0010972 negative regulation of G2/M transition of mitotic cell cycle; GO:0044763 single-organism cellular process; GO:0060828 regulation of canonical Wnt signaling pathway; GO:0043086 negative regulation of catalytic activity; GO:0033209 tumor necrosis factor-mediated signaling pathway; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0000165 MAPK cascade; GO:0019884 antigen processing and presentation of exogenous antigen; GO:1901575 organic substance catabolic process; GO:0007267 cell-cell signaling; GO:0002223 stimulatory C-type lectin receptor signaling pathway; GO:0030163 protein catabolic process; GO:0061136 regulation of proteasomal protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0060071 Wnt signaling pathway, planar cell polarity pathway; GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:0060548 negative regulation of cell death; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0016310 phosphorylation; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0043487 regulation of RNA stability; GO:0000209 protein polyubiquitination; GO:0023057 negative regulation of signaling; GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly; GO:0010648 negative regulation of cell communication; GO:0009889 regulation of biosynthetic process; GO:0009896 positive regulation of catabolic process; GO:0043620 regulation of DNA-templated transcription in response to stress; GO:0070482 response to oxygen levels; GO:0044248 cellular catabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0042176 regulation of protein catabolic process; GO:0038093 Fc receptor signaling pathway; GO:0050778 positive regulation of immune response; GO:0023014 signal transduction by protein phosphorylation; GO:1901215 negative regulation of neuron death; GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; GO:0006950 response to stress; GO:0016567 protein ubiquitination; GO:2000142 regulation of DNA-templated transcription, initiation; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:1903321 negative regulation of protein modification by small protein conjugation or removal; GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter; GO:0031398 positive regulation of protein ubiquitination; GO:0032446 protein modification by small protein conjugation; GO:0031325 positive regulation of cellular metabolic process; GO:0030177 positive regulation of Wnt signaling pathway; GO:1904668 positive regulation of ubiquitin protein ligase activity; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0043412 macromolecule modification; GO:0070646 protein modification by small protein removal; GO:0009968 negative regulation of signal transduction; GO:0031331 positive regulation of cellular catabolic process; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0031400 negative regulation of protein modification process; GO:0006796 phosphate-containing compound metabolic process; GO:0031396 regulation of protein ubiquitination; GO:2001141 regulation of RNA biosynthetic process; GO:0045930 negative regulation of mitotic cell cycle; GO:0007165 signal transduction; GO:2000144 positive regulation of DNA-templated transcription, initiation; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0034612 response to tumor necrosis factor; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0051726 regulation of cell cycle; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0034097 response to cytokine; GO:0031326 regulation of cellular biosynthetic process; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0198738 cell-cell signaling by wnt; GO:0010565 regulation of cellular ketone metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0036211 protein modification process; GO:0090175 regulation of establishment of planar polarity; GO:0045786 negative regulation of cell cycle; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:1901988 negative regulation of cell cycle phase transition; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0010498 proteasomal protein catabolic process; GO:0071704 organic substance metabolic process; GO:0045862 positive regulation of proteolysis; GO:2000027 regulation of organ morphogenesis; GO:0006468 protein phosphorylation; GO:0023056 positive regulation of signaling; GO:0001666 response to hypoxia; GO:0002757 immune response-activating signal transduction; GO:0010647 positive regulation of cell communication; GO:0071453 cellular response to oxygen levels; GO:0019221 cytokine-mediated signaling pathway; GO:0031397 negative regulation of protein ubiquitination; GO:0006355 regulation of transcription, DNA-templated; GO:0035556 intracellular signal transduction; GO:0019941 modification-dependent protein catabolic process; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:1901800 positive regulation of proteasomal protein catabolic process; GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia; GO:1902749 regulation of cell cycle G2/M phase transition; GO:0043488 regulation of mRNA stability; GO:0043085 positive regulation of catalytic activity; GO:0019882 antigen processing and presentation; GO:0050852 T cell receptor signaling pathway; GO:0002684 positive regulation of immune system process; GO:0038095 Fc-epsilon receptor signaling pathway; GO:0051248 negative regulation of protein metabolic process; GO:0022402 cell cycle process; GO:1902750 negative regulation of cell cycle G2/M phase transition; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0044089 positive regulation of cellular component biogenesis; GO:0060260 regulation of transcription initiation from RNA polymerase II promoter; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0002220 innate immune response activating cell surface receptor signaling pathway; GO:0007166 cell surface receptor signaling pathway; GO:0036503 ERAD pathway; GO:0071345 cellular response to cytokine stimulus; GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0051347 positive regulation of transferase activity; GO:1903362 regulation of cellular protein catabolic process; GO:0002758 innate immune response-activating signal transduction; GO:0031329 regulation of cellular catabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0009894 regulation of catabolic process; GO:0031323 regulation of cellular metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:2000058 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0010948 negative regulation of cell cycle process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0002682 regulation of immune system process; GO:0031145 anaphase-promoting complex-dependent catabolic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0007346 regulation of mitotic cell cycle; GO:0034976 response to endoplasmic reticulum stress; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:0051239 regulation of multicellular organismal process; GO:0031349 positive regulation of defense response; GO:0010628 positive regulation of gene expression; GO:1901987 regulation of cell cycle phase transition; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0010389 regulation of G2/M transition of mitotic cell cycle; GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; GO:0009966 regulation of signal transduction; GO:0038061 NIK/NF-kappaB signaling; GO:0071456 cellular response to hypoxia; GO:0002253 activation of immune response; GO:0051254 positive regulation of RNA metabolic process; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1904666 regulation of ubiquitin protein ligase activity; GO:0055085 transmembrane transport; GO:0051247 positive regulation of protein metabolic process; GO:0051438 regulation of ubiquitin-protein transferase activity; GO:0030111 regulation of Wnt signaling pathway; GO:0006793 phosphorus metabolic process; GO:0036293 response to decreased oxygen levels; GO:0031328 positive regulation of cellular biosynthetic process; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process; GO:0051444 negative regulation of ubiquitin-protein transferase activity; GO:0090090 negative regulation of canonical Wnt signaling pathway; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0006457 protein folding; GO:0035567 non-canonical Wnt signaling pathway; GO:1905330 regulation of morphogenesis of an epithelium; GO:0010646 regulation of cell communication; GO:0030433 ubiquitin-dependent ERAD pathway; GO:0007154 cell communication; GO:1901991 negative regulation of mitotic cell cycle phase transition; GO:0045088 regulation of innate immune response; GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I; GO:0031334 positive regulation of protein complex assembly; GO:0070887 cellular response to chemical stimulus; GO:0050851 antigen receptor-mediated signaling pathway; GO:0010468 regulation of gene expression; GO:0030178 negative regulation of Wnt signaling pathway; GO:0048002 antigen processing and presentation of peptide antigen; GO:0048522 positive regulation of cellular process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0051348 negative regulation of transferase activity; GO:0070647 protein modification by small protein conjugation or removal; GO:0042221 response to chemical; GO:0043254 regulation of protein complex assembly; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0019222 regulation of metabolic process; GO:2000026 regulation of multicellular organismal development; GO:0002218 activation of innate immune response; GO:1904667 negative regulation of ubiquitin protein ligase activity; GO:0071356 cellular response to tumor necrosis factor; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044087 regulation of cellular component biogenesis; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0016579 protein deubiquitination; GO:1903322 positive regulation of protein modification by small protein conjugation or removal; GO:0006508 proteolysis; GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:0009987 cellular process; GO:1901214 regulation of neuron death; GO:0033238 regulation of cellular amine metabolic process; GO:0043632 modification-dependent macromolecule catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0045089 positive regulation of innate immune response; GO:0044712 single-organism catabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition; GO:0031401 positive regulation of protein modification process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0051246 regulation of protein metabolic process; GO:0009057 macromolecule catabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0009967 positive regulation of signal transduction; GO:0051128 regulation of cellular component organization; GO:0045732 positive regulation of protein catabolic process; GO:0036294 cellular response to decreased oxygen levels; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005838 proteasome regulatory particle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:1905369 endopeptidase complex; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0022624 proteasome accessory complex; GO:0005622 intracellular; GO:0044464 cell part; GO:0044445 cytosolic part; GO:1905368 peptidase complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0000502 proteasome complex; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0031595 nuclear proteasome complex; GO:0008540 proteasome regulatory particle, base subcomplex; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0031597 cytosolic proteasome complex; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0016887 ATPase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003723 RNA binding; GO:0005524 ATP binding; GO:0036402 proteasome-activating ATPase activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003676 nucleic acid binding; GO:0042623 ATPase activity, coupled; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0017025 TBP-class protein binding; GO:0008134 transcription factor binding; GO:0036094 small molecule binding; ","K03062","PSMC1; 26S proteasome regulatory subunit T2","hsa03050 Proteasome - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa05203 Viral carcinogenesis - Homo sapiens (human); ","IPR003593; IPR003959; IPR027417; ","\"AAA+ ATPase domain; ATPase, AAA-type, core; P-loop containing nucleoside triphosphate hydrolase; \"\r"]
["P62241","40S ribosomal protein S8 OS=Homo sapiens OX=9606 GN=RPS8","RPS8",24.205,145.8,45.7,8,19,8,0.809,0.877,0.862,1.09,1.139,1.134,1.32,0.000599,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0072594 establishment of protein localization to organelle; GO:0006518 peptide metabolic process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0051649 establishment of localization in cell; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0070972 protein localization to endoplasmic reticulum; GO:0006364 rRNA processing; GO:0006413 translational initiation; GO:1901361 organic cyclic compound catabolic process; GO:0033365 protein localization to organelle; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0006412 translation; GO:0034470 ncRNA processing; GO:0006396 RNA processing; GO:0016072 rRNA metabolic process; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0072657 protein localization to membrane; GO:0043043 peptide biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0042254 ribosome biogenesis; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032774 RNA biosynthetic process; GO:0045047 protein targeting to ER; GO:0043603 cellular amide metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0006401 RNA catabolic process; GO:0016070 RNA metabolic process; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0019083 viral transcription; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0030490 maturation of SSU-rRNA; GO:0046907 intracellular transport; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0044267 cellular protein metabolic process; GO:0006613 cotranslational protein targeting to membrane; GO:0048519 negative regulation of biological process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0016032 viral process; GO:0019080 viral gene expression; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0006886 intracellular protein transport; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0034613 cellular protein localization; GO:0009059 macromolecule biosynthetic process; GO:0090150 establishment of protein localization to membrane; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0042274 ribosomal small subunit biogenesis; GO:0010629 negative regulation of gene expression; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0051179 localization; GO:0034660 ncRNA metabolic process; GO:0009056 catabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0071840 cellular component organization or biogenesis; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0030054 cell junction; GO:0015935 small ribosomal subunit; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0005925 focal adhesion; GO:0070013 intracellular organelle lumen; GO:0044391 ribosomal subunit; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0044445 cytosolic part; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0022626 cytosolic ribosome; GO:0043229 intracellular organelle; GO:0005840 ribosome; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0022627 cytosolic small ribosomal subunit; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005198 structural molecule activity; GO:0003735 structural constituent of ribosome; ","K02995","RP-S8e; small subunit ribosomal protein S8e","hsa03010 Ribosome - Homo sapiens (human); "]
["P62253","Ubiquitin-conjugating enzyme E2 G1 OS=Homo sapiens OX=9606 GN=UBE2G1","UBE2G1",19.509,4.5034,11.8,2,2,2,0.843,0.966,0.854,1.109,1.022,1.202,1.252,0.0247,"cytoplasm\r","GO:0043632 modification-dependent macromolecule catabolic process; GO:0070534 protein K63-linked ubiquitination; GO:0070936 protein K48-linked ubiquitination; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0044257 cellular protein catabolic process; GO:0016567 protein ubiquitination; GO:0019941 modification-dependent protein catabolic process; GO:0044267 cellular protein metabolic process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0000209 protein polyubiquitination; GO:0071704 organic substance metabolic process; GO:1901575 organic substance catabolic process; GO:0008152 metabolic process; GO:0032446 protein modification by small protein conjugation; GO:0030163 protein catabolic process; GO:0009057 macromolecule catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0044248 cellular catabolic process; GO:0006508 proteolysis; GO:0006464 cellular protein modification process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:0009056 catabolic process; GO:0009987 cellular process; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0031625 ubiquitin protein ligase binding; GO:0005515 protein binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0061630 ubiquitin protein ligase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0019787 ubiquitin-like protein transferase activity; GO:0061631 ubiquitin conjugating enzyme activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0061659 ubiquitin-like protein ligase activity; GO:0000166 nucleotide binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0004842 ubiquitin-protein transferase activity; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0061650 ubiquitin-like protein conjugating enzyme activity; GO:0044389 ubiquitin-like protein ligase binding; GO:0019899 enzyme binding; GO:0036094 small molecule binding; ","K10575","UBE2G1; ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]","hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human); hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); ","IPR016135; IPR000608; ","Ubiquitin-conjugating enzyme/RWD-like; Ubiquitin-conjugating enzyme E2; \r"]
["P62258","14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE","YWHAE",29.174,108.07,60.8,16,58,14,0.996,1.012,0.994,0.992,0.981,0.992,0.988,0.142,"cytoplasm\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0010941 regulation of cell death; GO:0065008 regulation of biological quality; GO:0021766 hippocampus development; GO:0007420 brain development; GO:0060271 cilium assembly; GO:0021987 cerebral cortex development; GO:0044237 cellular metabolic process; GO:0010821 regulation of mitochondrion organization; GO:0015031 protein transport; GO:0044782 cilium organization; GO:0048857 neural nucleus development; GO:0021537 telencephalon development; GO:0061337 cardiac conduction; GO:0021762 substantia nigra development; GO:0010466 negative regulation of peptidase activity; GO:0008152 metabolic process; GO:1901028 regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; GO:0009408 response to heat; GO:0032879 regulation of localization; GO:1903747 regulation of establishment of protein localization to mitochondrion; GO:0044093 positive regulation of molecular function; GO:0044057 regulation of system process; GO:0044770 cell cycle phase transition; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0090559 regulation of membrane permeability; GO:0044419 interspecies interaction between organisms; GO:0008104 protein localization; GO:0086011 membrane repolarization during action potential; GO:0007399 nervous system development; GO:0052548 regulation of endopeptidase activity; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0035305 negative regulation of dephosphorylation; GO:0035329 hippo signaling; GO:0051174 regulation of phosphorus metabolic process; GO:0030901 midbrain development; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0043269 regulation of ion transport; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0048870 cell motility; GO:0031323 regulation of cellular metabolic process; GO:0043086 negative regulation of catalytic activity; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0034762 regulation of transmembrane transport; GO:0006810 transport; GO:0000165 MAPK cascade; GO:0048513 animal organ development; GO:0080135 regulation of cellular response to stress; GO:0051336 regulation of hydrolase activity; GO:0046825 regulation of protein export from nucleus; GO:0044710 single-organism metabolic process; GO:0007417 central nervous system development; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0035304 regulation of protein dephosphorylation; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0051223 regulation of protein transport; GO:0099622 cardiac muscle cell membrane repolarization; GO:0032412 regulation of ion transmembrane transporter activity; GO:0000086 G2/M transition of mitotic cell cycle; GO:0060548 negative regulation of cell death; GO:0043068 positive regulation of programmed cell death; GO:0086013 membrane repolarization during cardiac muscle cell action potential; GO:0050794 regulation of cellular process; GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0033554 cellular response to stress; GO:0016310 phosphorylation; GO:0046907 intracellular transport; GO:0044707 single-multicellular organism process; GO:0010951 negative regulation of endopeptidase activity; GO:0034220 ion transmembrane transport; GO:0007006 mitochondrial membrane organization; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0043067 regulation of programmed cell death; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:1905477 positive regulation of protein localization to membrane; GO:0051239 regulation of multicellular organismal process; GO:0060341 regulation of cellular localization; GO:1900740 positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; GO:0051345 positive regulation of hydrolase activity; GO:0010959 regulation of metal ion transport; GO:0035308 negative regulation of protein dephosphorylation; GO:1901030 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; GO:0030900 forebrain development; GO:0032880 regulation of protein localization; GO:0007275 multicellular organism development; GO:0034613 cellular protein localization; GO:0009966 regulation of signal transduction; GO:0032409 regulation of transporter activity; GO:1904062 regulation of cation transmembrane transport; GO:0044772 mitotic cell cycle phase transition; GO:0023014 signal transduction by protein phosphorylation; GO:0045861 negative regulation of proteolysis; GO:0006950 response to stress; GO:0043547 positive regulation of GTPase activity; GO:0048731 system development; GO:1901379 regulation of potassium ion transmembrane transport; GO:0071702 organic substance transport; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0030031 cell projection assembly; GO:0045184 establishment of protein localization; GO:0055085 transmembrane transport; GO:0046822 regulation of nucleocytoplasmic transport; GO:1904951 positive regulation of establishment of protein localization; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0006811 ion transport; GO:0061024 membrane organization; GO:0002027 regulation of heart rate; GO:0006928 movement of cell or subcellular component; GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; GO:0044839 cell cycle G2/M phase transition; GO:0060306 regulation of membrane repolarization; GO:0043412 macromolecule modification; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0045936 negative regulation of phosphate metabolic process; GO:1903827 regulation of cellular protein localization; GO:0086009 membrane repolarization; GO:0003064 regulation of heart rate by hormone; GO:0051674 localization of cell; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:0006839 mitochondrial transport; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0021761 limbic system development; GO:0006796 phosphate-containing compound metabolic process; GO:0031400 negative regulation of protein modification process; GO:1903749 positive regulation of establishment of protein localization to mitochondrion; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0051130 positive regulation of cellular component organization; GO:2001233 regulation of apoptotic signaling pathway; GO:0007165 signal transduction; GO:0043266 regulation of potassium ion transport; GO:0051649 establishment of localization in cell; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:1902309 negative regulation of peptidyl-serine dephosphorylation; GO:0007005 mitochondrion organization; GO:0046824 positive regulation of nucleocytoplasmic transport; GO:0035303 regulation of dephosphorylation; GO:0001764 neuron migration; GO:0003062 regulation of heart rate by chemical signal; GO:0060322 head development; GO:0001508 action potential; GO:0033036 macromolecule localization; GO:0032502 developmental process; GO:2000116 regulation of cysteine-type endopeptidase activity; GO:0035637 multicellular organismal signaling; GO:0048522 positive regulation of cellular process; GO:0022898 regulation of transmembrane transporter activity; GO:0032386 regulation of intracellular transport; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051050 positive regulation of transport; GO:0010942 positive regulation of cell death; GO:0042391 regulation of membrane potential; GO:1902589 single-organism organelle organization; GO:0086001 cardiac muscle cell action potential; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0010638 positive regulation of organelle organization; GO:0030030 cell projection organization; GO:0034605 cellular response to heat; GO:1900034 regulation of cellular response to heat; GO:1901016 regulation of potassium ion transmembrane transporter activity; GO:0043087 regulation of GTPase activity; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0040011 locomotion; GO:0019220 regulation of phosphate metabolic process; GO:0036211 protein modification process; GO:0052547 regulation of peptidase activity; GO:0048856 anatomical structure development; GO:0051222 positive regulation of protein transport; GO:0021543 pallium development; GO:0016477 cell migration; GO:0016043 cellular component organization; GO:0043069 negative regulation of programmed cell death; GO:0090316 positive regulation of intracellular protein transport; GO:0060255 regulation of macromolecule metabolic process; GO:1903829 positive regulation of cellular protein localization; GO:1903522 regulation of blood circulation; GO:0043065 positive regulation of apoptotic process; GO:0097711 ciliary basal body docking; GO:0008016 regulation of heart contraction; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0022406 membrane docking; GO:0051346 negative regulation of hydrolase activity; GO:0070201 regulation of establishment of protein localization; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:1905475 regulation of protein localization to membrane; GO:0006468 protein phosphorylation; GO:0046902 regulation of mitochondrial membrane permeability; GO:0086091 regulation of heart rate by cardiac conduction; GO:0043066 negative regulation of apoptotic process; GO:0070925 organelle assembly; GO:0016032 viral process; GO:0023056 positive regulation of signaling; GO:0009266 response to temperature stimulus; GO:2000117 negative regulation of cysteine-type endopeptidase activity; GO:0006886 intracellular protein transport; GO:2001235 positive regulation of apoptotic signaling pathway; GO:0010647 positive regulation of cell communication; GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0033157 regulation of intracellular protein transport; GO:0009987 cellular process; GO:0035556 intracellular signal transduction; GO:0032388 positive regulation of intracellular transport; GO:0051049 regulation of transport; GO:0044802 single-organism membrane organization; GO:0033043 regulation of organelle organization; GO:1902308 regulation of peptidyl-serine dephosphorylation; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0010822 positive regulation of mitochondrion organization; GO:0051641 cellular localization; GO:0046827 positive regulation of protein export from nucleus; GO:0070727 cellular macromolecule localization; GO:0034765 regulation of ion transmembrane transport; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0010563 negative regulation of phosphorus metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0022402 cell cycle process; GO:0051128 regulation of cellular component organization; GO:0009967 positive regulation of signal transduction; GO:0007049 cell cycle; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0048770 pigment granule; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0005924 cell-substrate adherens junction; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0042470 melanosome; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0012506 vesicle membrane; GO:0005875 microtubule associated complex; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0030659 cytoplasmic vesicle membrane; GO:0005871 kinesin complex; GO:0030424 axon; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016597 amino acid binding; GO:0031625 ubiquitin protein ligase binding; GO:0050815 phosphoserine binding; GO:0005085 guanyl-nucleotide exchange factor activity; GO:0046983 protein dimerization activity; GO:0099106 ion channel regulator activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0003823 antigen binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0031406 carboxylic acid binding; GO:0042826 histone deacetylase binding; GO:0016247 channel regulator activity; GO:0017112 Rab guanyl-nucleotide exchange factor activity; GO:0023023 MHC protein complex binding; GO:0005488 binding; GO:0023026 MHC class II protein complex binding; GO:0045296 cadherin binding; GO:0043168 anion binding; GO:0003723 RNA binding; GO:0046982 protein heterodimerization activity; GO:0043167 ion binding; GO:0044877 macromolecular complex binding; GO:0043177 organic acid binding; GO:0045309 protein phosphorylated amino acid binding; GO:0051219 phosphoprotein binding; GO:0050839 cell adhesion molecule binding; GO:0015459 potassium channel regulator activity; GO:0003676 nucleic acid binding; GO:0044325 ion channel binding; GO:0019904 protein domain specific binding; GO:0005088 Ras guanyl-nucleotide exchange factor activity; GO:0044389 ubiquitin-like protein ligase binding; GO:0019899 enzyme binding; GO:0036094 small molecule binding; GO:0032403 protein complex binding; ","K06630","YWHAE; 14-3-3 protein epsilon","hsa04390 Hippo signaling pathway - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa04110 Cell cycle - Homo sapiens (human); hsa04722 Neurotrophin signaling pathway - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); hsa04114 Oocyte meiosis - Homo sapiens (human); hsa05203 Viral carcinogenesis - Homo sapiens (human); ","IPR023410; ","14-3-3 domain; \r"]
["P62269","40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18","RPS18",17.718,26.765,53.3,10,20,10,0.937,0.93,0.894,1.105,1.045,1.03,1.152,0.00554,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0072594 establishment of protein localization to organelle; GO:0006518 peptide metabolic process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0051649 establishment of localization in cell; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0070972 protein localization to endoplasmic reticulum; GO:0006364 rRNA processing; GO:0006413 translational initiation; GO:1901361 organic cyclic compound catabolic process; GO:0033365 protein localization to organelle; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0006412 translation; GO:0016072 rRNA metabolic process; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0072657 protein localization to membrane; GO:0043043 peptide biosynthetic process; GO:0042254 ribosome biogenesis; GO:1901360 organic cyclic compound metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032774 RNA biosynthetic process; GO:0045047 protein targeting to ER; GO:0043603 cellular amide metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0006401 RNA catabolic process; GO:0016070 RNA metabolic process; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0019083 viral transcription; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0046907 intracellular transport; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0044267 cellular protein metabolic process; GO:0006613 cotranslational protein targeting to membrane; GO:0048519 negative regulation of biological process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0016032 viral process; GO:0019080 viral gene expression; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0006886 intracellular protein transport; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0034613 cellular protein localization; GO:0009059 macromolecule biosynthetic process; GO:0090150 establishment of protein localization to membrane; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0051179 localization; GO:0009056 catabolic process; GO:0034660 ncRNA metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0071840 cellular component organization or biogenesis; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0030054 cell junction; GO:0031982 vesicle; GO:0015935 small ribosomal subunit; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0005925 focal adhesion; GO:0070013 intracellular organelle lumen; GO:0044391 ribosomal subunit; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0044445 cytosolic part; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0022626 cytosolic ribosome; GO:0043229 intracellular organelle; GO:0005840 ribosome; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0031012 extracellular matrix; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0022627 cytosolic small ribosomal subunit; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0019901 protein kinase binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0019900 kinase binding; GO:0003735 structural constituent of ribosome; GO:0005198 structural molecule activity; GO:0019899 enzyme binding; GO:0019843 rRNA binding; ","K02964","RP-S18e; small subunit ribosomal protein S18e","hsa03010 Ribosome - Homo sapiens (human); ","IPR010979; IPR027437; ","\"Ribosomal protein S13-like, H2TH; 30s ribosomal protein S13, C-terminal; \"\r"]
["P62304","Small nuclear ribonucleoprotein E OS=Homo sapiens OX=9606 GN=SNRPE","SNRPE",10.803,8.8451,25,2,4,2,0.942,0.923,0.861,1.124,1.016,1.071,1.178,0.0148,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0022618 ribonucleoprotein complex assembly; GO:0097659 nucleic acid-templated transcription; GO:0044699 single-organism process; GO:0051169 nuclear transport; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:0006353 DNA-templated transcription, termination; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0071826 ribonucleoprotein complex subunit organization; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0043170 macromolecule metabolic process; GO:0006396 RNA processing; GO:0008334 histone mRNA metabolic process; GO:0018130 heterocycle biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0044260 cellular macromolecule metabolic process; GO:0006913 nucleocytoplasmic transport; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0044707 single-multicellular organism process; GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0042303 molting cycle; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0008380 RNA splicing; GO:0034622 cellular macromolecular complex assembly; GO:0006369 termination of RNA polymerase II transcription; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0042633 hair cycle; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0043933 macromolecular complex subunit organization; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0051170 nuclear import; GO:0006366 transcription from RNA polymerase II promoter; GO:0010467 gene expression; GO:0051179 localization; GO:0000245 spliceosomal complex assembly; GO:0000387 spliceosomal snRNP assembly; GO:0071840 cellular component organization or biogenesis; ","GO:0005685 U1 snRNP; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0034719 SMN-Sm protein complex; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005689 U12-type spliceosomal complex; GO:0005683 U7 snRNP; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:1990234 transferase complex; GO:0005681 spliceosomal complex; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0034708 methyltransferase complex; GO:0097525 spliceosomal snRNP complex; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0034709 methylosome; GO:0005687 U4 snRNP; GO:0034715 pICln-Sm protein complex; GO:0071013 catalytic step 2 spliceosome; GO:1990904 ribonucleoprotein complex; GO:0030532 small nuclear ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005515 protein binding; GO:0005488 binding; GO:0003676 nucleic acid binding; ","K11097","SNRPE; small nuclear ribonucleoprotein E","hsa03040 Spliceosome - Homo sapiens (human); ","IPR001163; IPR010920; ","\"LSM domain, eukaryotic/archaea-type; LSM domain; \"\r"]
["P62308","Small nuclear ribonucleoprotein G OS=Homo sapiens OX=9606 GN=SNRPG","SNRPG",8.496,6.9517,34.2,3,10,3,0.843,0.931,1.032,1.097,0.993,1.002,1.102,0.209,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0022613 ribonucleoprotein complex biogenesis; GO:0022618 ribonucleoprotein complex assembly; GO:0006725 cellular aromatic compound metabolic process; GO:0097659 nucleic acid-templated transcription; GO:0051169 nuclear transport; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:0071704 organic substance metabolic process; GO:0006353 DNA-templated transcription, termination; GO:0000398 mRNA splicing, via spliceosome; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0071826 ribonucleoprotein complex subunit organization; GO:0046483 heterocycle metabolic process; GO:0022607 cellular component assembly; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0065003 macromolecular complex assembly; GO:0000375 RNA splicing, via transesterification reactions; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0006396 RNA processing; GO:0034622 cellular macromolecular complex assembly; GO:0008334 histone mRNA metabolic process; GO:0018130 heterocycle biosynthetic process; GO:0006369 termination of RNA polymerase II transcription; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0051641 cellular localization; GO:0006810 transport; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:0051170 nuclear import; GO:0090304 nucleic acid metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0006351 transcription, DNA-templated; GO:0006366 transcription from RNA polymerase II promoter; GO:0044260 cellular macromolecule metabolic process; GO:0006913 nucleocytoplasmic transport; GO:0010467 gene expression; GO:0051179 localization; GO:0000245 spliceosomal complex assembly; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0000387 spliceosomal snRNP assembly; GO:0071840 cellular component organization or biogenesis; ","GO:0005685 U1 snRNP; GO:0005686 U2 snRNP; GO:0005737 cytoplasm; GO:0005684 U2-type spliceosomal complex; GO:0032991 macromolecular complex; GO:0045495 pole plasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0043186 P granule; GO:0071011 precatalytic spliceosome; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0097526 spliceosomal tri-snRNP complex; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0034719 SMN-Sm protein complex; GO:0070013 intracellular organelle lumen; GO:0060293 germ plasm; GO:0044464 cell part; GO:0005622 intracellular; GO:0071004 U2-type prespliceosome; GO:0043227 membrane-bounded organelle; GO:0005689 U12-type spliceosomal complex; GO:0005683 U7 snRNP; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:1990234 transferase complex; GO:0005681 spliceosomal complex; GO:0005829 cytosol; GO:0034708 methyltransferase complex; GO:0097525 spliceosomal snRNP complex; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0034709 methylosome; GO:0005687 U4 snRNP; GO:0035770 ribonucleoprotein granule; GO:0071013 catalytic step 2 spliceosome; GO:0071010 prespliceosome; GO:1990904 ribonucleoprotein complex; GO:0043234 protein complex; GO:0030532 small nuclear ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0005682 U5 snRNP; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005515 protein binding; GO:0005488 binding; GO:0003676 nucleic acid binding; ","K11099","SNRPG; small nuclear ribonucleoprotein G","hsa03040 Spliceosome - Homo sapiens (human); ","IPR001163; IPR010920; ","\"LSM domain, eukaryotic/archaea-type; LSM domain; \"\r"]
["P62316","Small nuclear ribonucleoprotein Sm D2 OS=Homo sapiens OX=9606 GN=SNRPD2","SNRPD2",13.527,59.049,54.2,7,16,7,0.992,0.936,0.917,1.066,1.08,1.052,1.124,0.00898,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0022613 ribonucleoprotein complex biogenesis; GO:0022618 ribonucleoprotein complex assembly; GO:0006725 cellular aromatic compound metabolic process; GO:0051169 nuclear transport; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0071826 ribonucleoprotein complex subunit organization; GO:0046483 heterocycle metabolic process; GO:0022607 cellular component assembly; GO:0006139 nucleobase-containing compound metabolic process; GO:0065003 macromolecular complex assembly; GO:0000375 RNA splicing, via transesterification reactions; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0006396 RNA processing; GO:0034622 cellular macromolecular complex assembly; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0044238 primary metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0051641 cellular localization; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:0006810 transport; GO:0090304 nucleic acid metabolic process; GO:0051170 nuclear import; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0006913 nucleocytoplasmic transport; GO:0051179 localization; GO:0000245 spliceosomal complex assembly; GO:0016071 mRNA metabolic process; GO:0000387 spliceosomal snRNP assembly; GO:0071840 cellular component organization or biogenesis; ","GO:0005685 U1 snRNP; GO:0044421 extracellular region part; GO:0005686 U2 snRNP; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0071011 precatalytic spliceosome; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0097526 spliceosomal tri-snRNP complex; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0034719 SMN-Sm protein complex; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005689 U12-type spliceosomal complex; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0046540 U4/U6 x U5 tri-snRNP complex; GO:0031981 nuclear lumen; GO:1990234 transferase complex; GO:0005681 spliceosomal complex; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0034708 methyltransferase complex; GO:0097525 spliceosomal snRNP complex; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0034709 methylosome; GO:0005687 U4 snRNP; GO:0034715 pICln-Sm protein complex; GO:0071013 catalytic step 2 spliceosome; GO:1990904 ribonucleoprotein complex; GO:0043234 protein complex; GO:0030532 small nuclear ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0005682 U5 snRNP; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0070990 snRNP binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0043021 ribonucleoprotein complex binding; GO:1990446 U1 snRNP binding; ","K11096","SNRPD2; small nuclear ribonucleoprotein D2","hsa03040 Spliceosome - Homo sapiens (human); ","IPR001163; IPR010920; ","\"LSM domain, eukaryotic/archaea-type; LSM domain; \"\r"]
["P62333","26S proteasome regulatory subunit 10B OS=Homo sapiens OX=9606 GN=PSMC6","PSMC6",44.172,91.139,31.6,11,20,11,0.902,0.927,0.971,1.081,1.111,1.008,1.143,0.021,"cytoplasm\r","GO:0044700 single organism signaling; GO:0010608 posttranscriptional regulation of gene expression; GO:0051443 positive regulation of ubiquitin-protein transferase activity; GO:0009891 positive regulation of biosynthetic process; GO:0031347 regulation of defense response; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:1903364 positive regulation of cellular protein catabolic process; GO:0008152 metabolic process; GO:0044093 positive regulation of molecular function; GO:0090263 positive regulation of canonical Wnt signaling pathway; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0016055 Wnt signaling pathway; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0006521 regulation of cellular amino acid metabolic process; GO:0080090 regulation of primary metabolic process; GO:0010972 negative regulation of G2/M transition of mitotic cell cycle; GO:0044763 single-organism cellular process; GO:0060828 regulation of canonical Wnt signaling pathway; GO:0043086 negative regulation of catalytic activity; GO:0033209 tumor necrosis factor-mediated signaling pathway; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0000165 MAPK cascade; GO:0019884 antigen processing and presentation of exogenous antigen; GO:1901575 organic substance catabolic process; GO:0007267 cell-cell signaling; GO:0002223 stimulatory C-type lectin receptor signaling pathway; GO:0030163 protein catabolic process; GO:0061136 regulation of proteasomal protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0060071 Wnt signaling pathway, planar cell polarity pathway; GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0016310 phosphorylation; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0043487 regulation of RNA stability; GO:0000209 protein polyubiquitination; GO:0023057 negative regulation of signaling; GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly; GO:0010648 negative regulation of cell communication; GO:0009889 regulation of biosynthetic process; GO:0009896 positive regulation of catabolic process; GO:0043620 regulation of DNA-templated transcription in response to stress; GO:0070482 response to oxygen levels; GO:0044248 cellular catabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0042176 regulation of protein catabolic process; GO:0038093 Fc receptor signaling pathway; GO:0050778 positive regulation of immune response; GO:0023014 signal transduction by protein phosphorylation; GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; GO:0006950 response to stress; GO:0016567 protein ubiquitination; GO:2000142 regulation of DNA-templated transcription, initiation; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:1903321 negative regulation of protein modification by small protein conjugation or removal; GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter; GO:0031398 positive regulation of protein ubiquitination; GO:0032446 protein modification by small protein conjugation; GO:0031325 positive regulation of cellular metabolic process; GO:0030177 positive regulation of Wnt signaling pathway; GO:1904668 positive regulation of ubiquitin protein ligase activity; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0043412 macromolecule modification; GO:0070646 protein modification by small protein removal; GO:0009968 negative regulation of signal transduction; GO:0031331 positive regulation of cellular catabolic process; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0031400 negative regulation of protein modification process; GO:0006796 phosphate-containing compound metabolic process; GO:0031396 regulation of protein ubiquitination; GO:2001141 regulation of RNA biosynthetic process; GO:0045930 negative regulation of mitotic cell cycle; GO:0007165 signal transduction; GO:2000144 positive regulation of DNA-templated transcription, initiation; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0034612 response to tumor necrosis factor; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0051726 regulation of cell cycle; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0034097 response to cytokine; GO:0031326 regulation of cellular biosynthetic process; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0198738 cell-cell signaling by wnt; GO:0010565 regulation of cellular ketone metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0036211 protein modification process; GO:0090175 regulation of establishment of planar polarity; GO:0045786 negative regulation of cell cycle; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:1901988 negative regulation of cell cycle phase transition; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0010498 proteasomal protein catabolic process; GO:0071704 organic substance metabolic process; GO:0045862 positive regulation of proteolysis; GO:2000027 regulation of organ morphogenesis; GO:0006468 protein phosphorylation; GO:0023056 positive regulation of signaling; GO:0001666 response to hypoxia; GO:0002757 immune response-activating signal transduction; GO:0010647 positive regulation of cell communication; GO:0071453 cellular response to oxygen levels; GO:0019221 cytokine-mediated signaling pathway; GO:0031397 negative regulation of protein ubiquitination; GO:0006355 regulation of transcription, DNA-templated; GO:0019941 modification-dependent protein catabolic process; GO:0035556 intracellular signal transduction; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:1901800 positive regulation of proteasomal protein catabolic process; GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia; GO:1902749 regulation of cell cycle G2/M phase transition; GO:0043488 regulation of mRNA stability; GO:0043085 positive regulation of catalytic activity; GO:0019882 antigen processing and presentation; GO:0050852 T cell receptor signaling pathway; GO:0002684 positive regulation of immune system process; GO:0038095 Fc-epsilon receptor signaling pathway; GO:0051248 negative regulation of protein metabolic process; GO:0022402 cell cycle process; GO:1902750 negative regulation of cell cycle G2/M phase transition; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0044089 positive regulation of cellular component biogenesis; GO:0060260 regulation of transcription initiation from RNA polymerase II promoter; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0002220 innate immune response activating cell surface receptor signaling pathway; GO:0007166 cell surface receptor signaling pathway; GO:0036503 ERAD pathway; GO:0071345 cellular response to cytokine stimulus; GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0051347 positive regulation of transferase activity; GO:1903362 regulation of cellular protein catabolic process; GO:0002758 innate immune response-activating signal transduction; GO:0031329 regulation of cellular catabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0009894 regulation of catabolic process; GO:0031323 regulation of cellular metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:2000058 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0010948 negative regulation of cell cycle process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0002682 regulation of immune system process; GO:0031145 anaphase-promoting complex-dependent catabolic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0007346 regulation of mitotic cell cycle; GO:0034976 response to endoplasmic reticulum stress; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:0051239 regulation of multicellular organismal process; GO:0031349 positive regulation of defense response; GO:0010628 positive regulation of gene expression; GO:1901987 regulation of cell cycle phase transition; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0010389 regulation of G2/M transition of mitotic cell cycle; GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; GO:0009966 regulation of signal transduction; GO:0038061 NIK/NF-kappaB signaling; GO:0071456 cellular response to hypoxia; GO:0002253 activation of immune response; GO:0051254 positive regulation of RNA metabolic process; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1904666 regulation of ubiquitin protein ligase activity; GO:0055085 transmembrane transport; GO:0051247 positive regulation of protein metabolic process; GO:0051438 regulation of ubiquitin-protein transferase activity; GO:0030111 regulation of Wnt signaling pathway; GO:0006793 phosphorus metabolic process; GO:0036293 response to decreased oxygen levels; GO:0031328 positive regulation of cellular biosynthetic process; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process; GO:0051444 negative regulation of ubiquitin-protein transferase activity; GO:0090090 negative regulation of canonical Wnt signaling pathway; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0035567 non-canonical Wnt signaling pathway; GO:1905330 regulation of morphogenesis of an epithelium; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0030433 ubiquitin-dependent ERAD pathway; GO:1901991 negative regulation of mitotic cell cycle phase transition; GO:0045088 regulation of innate immune response; GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I; GO:0031334 positive regulation of protein complex assembly; GO:0070887 cellular response to chemical stimulus; GO:0050851 antigen receptor-mediated signaling pathway; GO:0010468 regulation of gene expression; GO:0030178 negative regulation of Wnt signaling pathway; GO:0048002 antigen processing and presentation of peptide antigen; GO:0048522 positive regulation of cellular process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0051348 negative regulation of transferase activity; GO:0070647 protein modification by small protein conjugation or removal; GO:0042221 response to chemical; GO:0043254 regulation of protein complex assembly; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0019222 regulation of metabolic process; GO:2000026 regulation of multicellular organismal development; GO:0002218 activation of innate immune response; GO:1904667 negative regulation of ubiquitin protein ligase activity; GO:0071356 cellular response to tumor necrosis factor; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044087 regulation of cellular component biogenesis; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0016579 protein deubiquitination; GO:1903322 positive regulation of protein modification by small protein conjugation or removal; GO:0006508 proteolysis; GO:0009987 cellular process; GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:0033238 regulation of cellular amine metabolic process; GO:0043632 modification-dependent macromolecule catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0045089 positive regulation of innate immune response; GO:0044712 single-organism catabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition; GO:0031401 positive regulation of protein modification process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0051246 regulation of protein metabolic process; GO:0009057 macromolecule catabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0009967 positive regulation of signal transduction; GO:0051128 regulation of cellular component organization; GO:0045732 positive regulation of protein catabolic process; GO:0036294 cellular response to decreased oxygen levels; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005838 proteasome regulatory particle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:1905369 endopeptidase complex; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0022624 proteasome accessory complex; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0044445 cytosolic part; GO:1905368 peptidase complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0000502 proteasome complex; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0031595 nuclear proteasome complex; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0008540 proteasome regulatory particle, base subcomplex; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0031597 cytosolic proteasome complex; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0016887 ATPase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0042802 identical protein binding; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0030674 protein binding, bridging; GO:0036402 proteasome-activating ATPase activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0042623 ATPase activity, coupled; GO:0032555 purine ribonucleotide binding; GO:0060090 binding, bridging; GO:0001883 purine nucleoside binding; GO:0017025 TBP-class protein binding; GO:0008134 transcription factor binding; GO:0036094 small molecule binding; ","K03064","PSMC6; 26S proteasome regulatory subunit T4","hsa03050 Proteasome - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); ","IPR003959; IPR003593; IPR027417; ","\"ATPase, AAA-type, core; AAA+ ATPase domain; P-loop containing nucleoside triphosphate hydrolase; \"\r"]
["P62491","Ras-related protein Rab-11A OS=Homo sapiens OX=9606 GN=RAB11A","RAB11A",24.393,9.2824,54.6,11,26,1,0.877,0.968,0.943,1.114,1.05,1.066,1.159,0.0128,"cytoskeleton\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0060627 regulation of vesicle-mediated transport; GO:0030335 positive regulation of cell migration; GO:0065008 regulation of biological quality; GO:0090002 establishment of protein localization to plasma membrane; GO:0060271 cilium assembly; GO:0010564 regulation of cell cycle process; GO:0015031 protein transport; GO:0044782 cilium organization; GO:0045927 positive regulation of growth; GO:0001558 regulation of cell growth; GO:1903729 regulation of plasma membrane organization; GO:0051875 pigment granule localization; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0032535 regulation of cellular component size; GO:0032400 melanosome localization; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0036258 multivesicular body assembly; GO:0033365 protein localization to organelle; GO:0090068 positive regulation of cell cycle process; GO:0008104 protein localization; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0000278 mitotic cell cycle; GO:0007059 chromosome segregation; GO:0010632 regulation of epithelial cell migration; GO:0072657 protein localization to membrane; GO:0030307 positive regulation of cell growth; GO:0048699 generation of neurons; GO:0031346 positive regulation of cell projection organization; GO:0045773 positive regulation of axon extension; GO:0044763 single-organism cellular process; GO:0048168 regulation of neuronal synaptic plasticity; GO:1902751 positive regulation of cell cycle G2/M phase transition; GO:0098877 neurotransmitter receptor transport to plasma membrane; GO:0007009 plasma membrane organization; GO:0007264 small GTPase mediated signal transduction; GO:0051272 positive regulation of cellular component movement; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:0000226 microtubule cytoskeleton organization; GO:0045931 positive regulation of mitotic cell cycle; GO:0030104 water homeostasis; GO:0051223 regulation of protein transport; GO:0090307 mitotic spindle assembly; GO:0051301 cell division; GO:0048169 regulation of long-term neuronal synaptic plasticity; GO:0097435 supramolecular fiber organization; GO:0051094 positive regulation of developmental process; GO:0010975 regulation of neuron projection development; GO:0050794 regulation of cellular process; GO:0051640 organelle localization; GO:0044707 single-multicellular organism process; GO:0046907 intracellular transport; GO:0007346 regulation of mitotic cell cycle; GO:1903076 regulation of protein localization to plasma membrane; GO:0007051 spindle organization; GO:0007080 mitotic metaphase plate congression; GO:2000147 positive regulation of cell motility; GO:1903078 positive regulation of protein localization to plasma membrane; GO:1903047 mitotic cell cycle process; GO:1905477 positive regulation of protein localization to membrane; GO:1901989 positive regulation of cell cycle phase transition; GO:1990778 protein localization to cell periphery; GO:0051239 regulation of multicellular organismal process; GO:0045597 positive regulation of cell differentiation; GO:0099637 neurotransmitter receptor transport; GO:0060341 regulation of cellular localization; GO:1902578 single-organism localization; GO:0000910 cytokinesis; GO:0050772 positive regulation of axonogenesis; GO:1901987 regulation of cell cycle phase transition; GO:2000145 regulation of cell motility; GO:0010389 regulation of G2/M transition of mitotic cell cycle; GO:1902580 single-organism cellular localization; GO:0007275 multicellular organism development; GO:0032880 regulation of protein localization; GO:0007010 cytoskeleton organization; GO:0034613 cellular protein localization; GO:0090150 establishment of protein localization to membrane; GO:0048878 chemical homeostasis; GO:0048167 regulation of synaptic plasticity; GO:0045787 positive regulation of cell cycle; GO:1904377 positive regulation of protein localization to cell periphery; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0050804 modulation of synaptic transmission; GO:0099638 endosome to plasma membrane protein transport; GO:0051960 regulation of nervous system development; GO:0060284 regulation of cell development; GO:0003014 renal system process; GO:0016192 vesicle-mediated transport; GO:0030334 regulation of cell migration; GO:0071702 organic substance transport; GO:0051656 establishment of organelle localization; GO:0007017 microtubule-based process; GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane; GO:0050770 regulation of axonogenesis; GO:0030031 cell projection assembly; GO:0031122 cytoplasmic microtubule organization; GO:0045184 establishment of protein localization; GO:0030182 neuron differentiation; GO:0072659 protein localization to plasma membrane; GO:0051276 chromosome organization; GO:0030516 regulation of axon extension; GO:0010976 positive regulation of neuron projection development; GO:0098969 neurotransmitter receptor transport to postsynaptic membrane; GO:0050891 multicellular organismal water homeostasis; GO:0006996 organelle organization; GO:0098813 nuclear chromosome segregation; GO:0061024 membrane organization; GO:0010796 regulation of multivesicular body size; GO:0061387 regulation of extent of cell growth; GO:0043473 pigmentation; GO:0000280 nuclear division; GO:0050769 positive regulation of neurogenesis; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0033059 cellular pigmentation; GO:1903827 regulation of cellular protein localization; GO:0006887 exocytosis; GO:0010256 endomembrane system organization; GO:0045666 positive regulation of neuron differentiation; GO:0072594 establishment of protein localization to organelle; GO:0040017 positive regulation of locomotion; GO:0023051 regulation of signaling; GO:0048666 neuron development; GO:0007067 mitotic nuclear division; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0097734 extracellular exosome biogenesis; GO:0048871 multicellular organismal homeostasis; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0007165 signal transduction; GO:0000819 sister chromatid segregation; GO:0050000 chromosome localization; GO:1904375 regulation of protein localization to cell periphery; GO:0010646 regulation of cell communication; GO:0051225 spindle assembly; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:1990126 retrograde transport, endosome to plasma membrane; GO:0051904 pigment granule transport; GO:0033036 macromolecule localization; GO:0010720 positive regulation of cell development; GO:0051726 regulation of cell cycle; GO:0003091 renal water homeostasis; GO:0032502 developmental process; GO:0051650 establishment of vesicle localization; GO:0048639 positive regulation of developmental growth; GO:0051962 positive regulation of nervous system development; GO:0048522 positive regulation of cellular process; GO:0036257 multivesicular body organization; GO:0023052 signaling; GO:0030953 astral microtubule organization; GO:1902582 single-organism intracellular transport; GO:0016197 endosomal transport; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0045664 regulation of neuron differentiation; GO:0030030 cell projection organization; GO:0032940 secretion by cell; GO:0051036 regulation of endosome size; GO:1902850 microtubule cytoskeleton organization involved in mitosis; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0016043 cellular component organization; GO:0035418 protein localization to synapse; GO:0040008 regulation of growth; GO:1903539 protein localization to postsynaptic membrane; GO:1903829 positive regulation of cellular protein localization; GO:0048285 organelle fission; GO:0010770 positive regulation of cell morphogenesis involved in differentiation; GO:0097711 ciliary basal body docking; GO:0031344 regulation of cell projection organization; GO:0050896 response to stimulus; GO:0051310 metaphase plate congression; GO:0048638 regulation of developmental growth; GO:0022406 membrane docking; GO:0070201 regulation of establishment of protein localization; GO:0048468 cell development; GO:1903540 establishment of protein localization to postsynaptic membrane; GO:0042592 homeostatic process; GO:1905475 regulation of protein localization to membrane; GO:0030154 cell differentiation; GO:0008361 regulation of cell size; GO:0070925 organelle assembly; GO:0051905 establishment of pigment granule localization; GO:0051648 vesicle localization; GO:0032402 melanosome transport; GO:0007052 mitotic spindle organization; GO:0009987 cellular process; GO:0048227 plasma membrane to endosome transport; GO:0045595 regulation of cell differentiation; GO:0050878 regulation of body fluid levels; GO:0003008 system process; GO:0098876 vesicle-mediated transport to the plasma membrane; GO:0035556 intracellular signal transduction; GO:0051303 establishment of chromosome localization; GO:0051049 regulation of transport; GO:0044802 single-organism membrane organization; GO:0000070 mitotic sister chromatid segregation; GO:0016050 vesicle organization; GO:0010634 positive regulation of epithelial cell migration; GO:1902749 regulation of cell cycle G2/M phase transition; GO:0031175 neuron projection development; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0070727 cellular macromolecule localization; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0090066 regulation of anatomical structure size; GO:0032401 establishment of melanosome localization; GO:0099639 neurotransmitter receptor transport, endosome to plasma membrane; GO:0051128 regulation of cellular component organization; GO:0022402 cell cycle process; GO:0010971 positive regulation of G2/M transition of mitotic cell cycle; GO:1990182 exosomal secretion; GO:0040012 regulation of locomotion; GO:1901992 positive regulation of mitotic cell cycle phase transition; GO:0022604 regulation of cell morphogenesis; GO:0007032 endosome organization; GO:0007049 cell cycle; GO:0050767 regulation of neurogenesis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0005623 cell; GO:0032155 cell division site part; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0098791 Golgi subcompartment; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0005771 multivesicular body; GO:0010008 endosome membrane; GO:0042995 cell projection; GO:0000922 spindle pole; GO:0005770 late endosome; GO:0044430 cytoskeletal part; GO:0012506 vesicle membrane; GO:0044440 endosomal part; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0030424 axon; GO:0043231 intracellular membrane-bounded organelle; GO:0030133 transport vesicle; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0055038 recycling endosome membrane; GO:0055037 recycling endosome; GO:0005856 cytoskeleton; GO:0015630 microtubule cytoskeleton; GO:0044464 cell part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0044431 Golgi apparatus part; GO:0005768 endosome; GO:0032154 cleavage furrow; GO:0030139 endocytic vesicle; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0097610 cell surface furrow; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0032153 cell division site; GO:0012505 endomembrane system; GO:0045335 phagocytic vesicle; GO:0005829 cytosol; GO:0005819 spindle; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0005802 trans-Golgi network; GO:0009986 cell surface; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; GO:0031984 organelle subcompartment; ","GO:0000149 SNARE binding; GO:1901265 nucleoside phosphate binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0031489 myosin V binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0008092 cytoskeletal protein binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0008017 microtubule binding; GO:0032550 purine ribonucleoside binding; GO:0003924 GTPase activity; GO:0043168 anion binding; GO:0019001 guanyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0015631 tubulin binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0032561 guanyl ribonucleotide binding; GO:0017022 myosin binding; GO:0019905 syntaxin binding; GO:0036094 small molecule binding; ","K07904","RAB11A; Ras-related protein Rab-11A","hsa04144 Endocytosis - Homo sapiens (human); hsa04972 Pancreatic secretion - Homo sapiens (human); hsa04962 Vasopressin-regulated water reabsorption - Homo sapiens (human); hsa04961 Endocrine and other factor-regulated calcium reabsorption - Homo sapiens (human); ","IPR005225; IPR027417; ","Small GTP-binding protein domain; P-loop containing nucleoside triphosphate hydrolase; \r"]
["P62495","Eukaryotic peptide chain release factor subunit 1 OS=Homo sapiens OX=9606 GN=ETF1","ETF1",49.03,35.801,17.6,8,11,8,0.981,0.881,0.916,1.11,1.065,1.092,1.176,0.00838,"cytoplasm\r","GO:0006518 peptide metabolic process; GO:0010608 posttranscriptional regulation of gene expression; GO:0006449 regulation of translational termination; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0032259 methylation; GO:0043241 protein complex disassembly; GO:0008213 protein alkylation; GO:0008152 metabolic process; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:1901361 organic cyclic compound catabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0006412 translation; GO:0010468 regulation of gene expression; GO:0071822 protein complex subunit organization; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0043043 peptide biosynthetic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0016070 RNA metabolic process; GO:0006401 RNA catabolic process; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0006415 translational termination; GO:0090304 nucleic acid metabolic process; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006464 cellular protein modification process; GO:0043244 regulation of protein complex disassembly; GO:0036211 protein modification process; GO:0016071 mRNA metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0044267 cellular protein metabolic process; GO:0048519 negative regulation of biological process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0006479 protein methylation; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0043624 cellular protein complex disassembly; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0006807 nitrogen compound metabolic process; GO:0032984 macromolecular complex disassembly; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0044249 cellular biosynthetic process; GO:0034248 regulation of cellular amide metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0051246 regulation of protein metabolic process; GO:0006417 regulation of translation; GO:0043414 macromolecule methylation; GO:0009057 macromolecule catabolic process; GO:0022411 cellular component disassembly; GO:0010467 gene expression; GO:0051128 regulation of cellular component organization; GO:0043604 amide biosynthetic process; GO:0043412 macromolecule modification; GO:0009056 catabolic process; GO:0065007 biological regulation; GO:0046700 heterocycle catabolic process; GO:0071840 cellular component organization or biogenesis; GO:1901564 organonitrogen compound metabolic process; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0044444 cytoplasmic part; ","GO:0008079 translation termination factor activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0043022 ribosome binding; GO:0003723 RNA binding; GO:0008135 translation factor activity, RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0044877 macromolecular complex binding; GO:0005515 protein binding; GO:0016149 translation release factor activity, codon specific; GO:0043021 ribonucleoprotein complex binding; GO:0003747 translation release factor activity; ","K03265","ETF1; peptide chain release factor subunit 1","hsa03015 mRNA surveillance pathway - Homo sapiens (human); ","IPR005141; IPR029064; IPR005142; IPR005140; IPR024049; ","\"eRF1 domain 2; 50S ribosomal protein L30e-like; eRF1 domain 3; eRF1 domain 1/Pelota-like; Peptide Chain Release Factor eRF1/aRF1, N-terminal; \"\r"]
["P62701","40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X","RPS4X",29.597,93.258,54,15,34,15,0.931,0.929,0.906,1.136,1.074,1.069,1.185,0.00136,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0006518 peptide metabolic process; GO:0032270 positive regulation of cellular protein metabolic process; GO:0010608 posttranscriptional regulation of gene expression; GO:0009891 positive regulation of biosynthetic process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0070972 protein localization to endoplasmic reticulum; GO:0006364 rRNA processing; GO:0033365 protein localization to organelle; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0008104 protein localization; GO:0006396 RNA processing; GO:0018130 heterocycle biosynthetic process; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0072657 protein localization to membrane; GO:0080090 regulation of primary metabolic process; GO:0042254 ribosome biogenesis; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032774 RNA biosynthetic process; GO:0045047 protein targeting to ER; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0046907 intracellular transport; GO:0042127 regulation of cell proliferation; GO:0044267 cellular protein metabolic process; GO:0048519 negative regulation of biological process; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0051171 regulation of nitrogen compound metabolic process; GO:0044248 cellular catabolic process; GO:0007275 multicellular organism development; GO:0034655 nucleobase-containing compound catabolic process; GO:0034613 cellular protein localization; GO:0090150 establishment of protein localization to membrane; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0034248 regulation of cellular amide metabolic process; GO:0045184 establishment of protein localization; GO:0051247 positive regulation of protein metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0051179 localization; GO:0031328 positive regulation of cellular biosynthetic process; GO:0008284 positive regulation of cell proliferation; GO:1901564 organonitrogen compound metabolic process; GO:0072594 establishment of protein localization to organelle; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0051649 establishment of localization in cell; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0006413 translational initiation; GO:1901361 organic cyclic compound catabolic process; GO:0006412 translation; GO:0033036 macromolecule localization; GO:0034470 ncRNA processing; GO:0016072 rRNA metabolic process; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0045727 positive regulation of translation; GO:0043043 peptide biosynthetic process; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0006401 RNA catabolic process; GO:0016070 RNA metabolic process; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0090304 nucleic acid metabolic process; GO:0019222 regulation of metabolic process; GO:0019083 viral transcription; GO:0048856 anatomical structure development; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0006613 cotranslational protein targeting to membrane; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0016032 viral process; GO:0019080 viral gene expression; GO:0006886 intracellular protein transport; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0070727 cellular macromolecule localization; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0051246 regulation of protein metabolic process; GO:0006417 regulation of translation; GO:0044767 single-organism developmental process; GO:0009057 macromolecule catabolic process; GO:0034250 positive regulation of cellular amide metabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0009056 catabolic process; GO:0034660 ncRNA metabolic process; GO:0065007 biological regulation; GO:0046700 heterocycle catabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0030054 cell junction; GO:0031982 vesicle; GO:0015935 small ribosomal subunit; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0005925 focal adhesion; GO:0070013 intracellular organelle lumen; GO:0044391 ribosomal subunit; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0044445 cytosolic part; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0022626 cytosolic ribosome; GO:0043229 intracellular organelle; GO:0005840 ribosome; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031012 extracellular matrix; GO:0005634 nucleus; GO:0035770 ribonucleoprotein granule; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0022627 cytosolic small ribosomal subunit; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0005844 polysome; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0005198 structural molecule activity; GO:0003735 structural constituent of ribosome; GO:0019843 rRNA binding; ","K02987","RP-S4e; small subunit ribosomal protein S4e","hsa03010 Ribosome - Homo sapiens (human); ","IPR013845; IPR005824; IPR032277; IPR002942; IPR013843; ","\"Ribosomal protein S4e, central region; KOW; 40S ribosomal protein S4, C-terminal domain; RNA-binding S4 domain; Ribosomal protein S4e, N-terminal; \"\r"]
["P62753","40S ribosomal protein S6 OS=Homo sapiens OX=9606 GN=RPS6","RPS6",28.68,48.699,26.5,7,13,7,0.903,0.885,0.916,1.096,1.077,1.056,1.194,0.000264,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0022613 ribonucleoprotein complex biogenesis; GO:0010941 regulation of cell death; GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0006518 peptide metabolic process; GO:0022414 reproductive process; GO:0002262 myeloid cell homeostasis; GO:0042593 glucose homeostasis; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0042110 T cell activation; GO:0031929 TOR signaling; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0061515 myeloid cell development; GO:0070972 protein localization to endoplasmic reticulum; GO:0006364 rRNA processing; GO:0044702 single organism reproductive process; GO:0043029 T cell homeostasis; GO:0044770 cell cycle phase transition; GO:0019538 protein metabolic process; GO:0033365 protein localization to organelle; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0008104 protein localization; GO:0009790 embryo development; GO:0048598 embryonic morphogenesis; GO:0006396 RNA processing; GO:0051716 cellular response to stimulus; GO:0000278 mitotic cell cycle; GO:0018130 heterocycle biosynthetic process; GO:0003006 developmental process involved in reproduction; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0072657 protein localization to membrane; GO:0019953 sexual reproduction; GO:0044763 single-organism cellular process; GO:0048821 erythrocyte development; GO:0042254 ribosome biogenesis; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032774 RNA biosynthetic process; GO:0002520 immune system development; GO:0045047 protein targeting to ER; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0048872 homeostasis of number of cells; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0048513 animal organ development; GO:0030218 erythrocyte differentiation; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0048609 multicellular organismal reproductive process; GO:0060548 negative regulation of cell death; GO:0016071 mRNA metabolic process; GO:0002260 lymphocyte homeostasis; GO:1901362 organic cyclic compound biosynthetic process; GO:0043068 positive regulation of programmed cell death; GO:0000003 reproduction; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0044707 single-multicellular organism process; GO:0007346 regulation of mitotic cell cycle; GO:0001890 placenta development; GO:0044267 cellular protein metabolic process; GO:0043067 regulation of programmed cell death; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0030098 lymphocyte differentiation; GO:0044270 cellular nitrogen compound catabolic process; GO:0009653 anatomical structure morphogenesis; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0007093 mitotic cell cycle checkpoint; GO:0044248 cellular catabolic process; GO:0033500 carbohydrate homeostasis; GO:0034655 nucleobase-containing compound catabolic process; GO:0007275 multicellular organism development; GO:0034613 cellular protein localization; GO:0061458 reproductive system development; GO:0030217 T cell differentiation; GO:0090150 establishment of protein localization to membrane; GO:0048878 chemical homeostasis; GO:0022605 oogenesis stage; GO:0044772 mitotic cell cycle phase transition; GO:0002285 lymphocyte activation involved in immune response; GO:0048731 system development; GO:0070227 lymphocyte apoptotic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0008283 cell proliferation; GO:0071702 organic substance transport; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:0002263 cell activation involved in immune response; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0045184 establishment of protein localization; GO:0006996 organelle organization; GO:0001775 cell activation; GO:0000280 nuclear division; GO:0012501 programmed cell death; GO:0006955 immune response; GO:0051179 localization; GO:0002309 T cell proliferation involved in immune response; GO:1901564 organonitrogen compound metabolic process; GO:0072594 establishment of protein localization to organelle; GO:0048869 cellular developmental process; GO:0007067 mitotic nuclear division; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0034101 erythrocyte homeostasis; GO:0006612 protein targeting to membrane; GO:0007165 signal transduction; GO:0045930 negative regulation of mitotic cell cycle; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0006915 apoptotic process; GO:0006413 translational initiation; GO:0000075 cell cycle checkpoint; GO:1901361 organic cyclic compound catabolic process; GO:0006412 translation; GO:0033036 macromolecule localization; GO:0051726 regulation of cell cycle; GO:0032943 mononuclear cell proliferation; GO:0032502 developmental process; GO:0034470 ncRNA processing; GO:0016072 rRNA metabolic process; GO:0010468 regulation of gene expression; GO:0048477 oogenesis; GO:0033077 T cell differentiation in thymus; GO:0002521 leukocyte differentiation; GO:0043043 peptide biosynthetic process; GO:0048608 reproductive structure development; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0001776 leukocyte homeostasis; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0010942 positive regulation of cell death; GO:0006401 RNA catabolic process; GO:0016070 RNA metabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0022412 cellular process involved in reproduction in multicellular organism; GO:0070661 leukocyte proliferation; GO:0019222 regulation of metabolic process; GO:0019083 viral transcription; GO:0048856 anatomical structure development; GO:0071887 leukocyte apoptotic process; GO:0016043 cellular component organization; GO:0045786 negative regulation of cell cycle; GO:0043069 negative regulation of programmed cell death; GO:0006725 cellular aromatic compound metabolic process; GO:0002252 immune effector process; GO:0007292 female gamete generation; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0048285 organelle fission; GO:0043065 positive regulation of apoptotic process; GO:0002286 T cell activation involved in immune response; GO:0006613 cotranslational protein targeting to membrane; GO:0046651 lymphocyte proliferation; GO:1901566 organonitrogen compound biosynthetic process; GO:0006924 activation-induced cell death of T cells; GO:0070231 T cell apoptotic process; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0071704 organic substance metabolic process; GO:0007369 gastrulation; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:0043066 negative regulation of apoptotic process; GO:0016032 viral process; GO:0019080 viral gene expression; GO:0006886 intracellular protein transport; GO:0007281 germ cell development; GO:0034641 cellular nitrogen compound metabolic process; GO:0000082 G1/S transition of mitotic cell cycle; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0030099 myeloid cell differentiation; GO:0042274 ribosomal small subunit biogenesis; GO:0044843 cell cycle G1/S phase transition; GO:0035556 intracellular signal transduction; GO:0010629 negative regulation of gene expression; GO:0006807 nitrogen compound metabolic process; GO:0046649 lymphocyte activation; GO:0048518 positive regulation of biological process; GO:0048534 hematopoietic or lymphoid organ development; GO:0030097 hemopoiesis; GO:0007276 gamete generation; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0002366 leukocyte activation involved in immune response; GO:0032504 multicellular organism reproduction; GO:0070727 cellular macromolecule localization; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0044703 multi-organism reproductive process; GO:0009057 macromolecule catabolic process; GO:0042098 T cell proliferation; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0022402 cell cycle process; GO:0009056 catabolic process; GO:0034660 ncRNA metabolic process; GO:0042981 regulation of apoptotic process; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:0046700 heterocycle catabolic process; ","GO:0016020 membrane; GO:0030425 dendrite; GO:0015935 small ribosomal subunit; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044391 ribosomal subunit; GO:0044464 cell part; GO:0048471 perinuclear region of cytoplasm; GO:0043005 neuron projection; GO:0044445 cytosolic part; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043233 organelle lumen; GO:0022626 cytosolic ribosome; GO:0005840 ribosome; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0036477 somatodendritic compartment; GO:0005634 nucleus; GO:0035770 ribonucleoprotein granule; GO:0044297 cell body; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0022627 cytosolic small ribosomal subunit; GO:0044444 cytoplasmic part; GO:0005844 polysome; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0019901 protein kinase binding; GO:0005515 protein binding; GO:0019900 kinase binding; GO:0005198 structural molecule activity; GO:0003735 structural constituent of ribosome; GO:0019899 enzyme binding; ","K02991","RP-S6e; small subunit ribosomal protein S6e","hsa04066 HIF-1 signaling pathway - Homo sapiens (human); hsa04371 Apelin signaling pathway - Homo sapiens (human); hsa04910 Insulin signaling pathway - Homo sapiens (human); hsa04150 mTOR signaling pathway - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa03010 Ribosome - Homo sapiens (human); hsa01521 EGFR tyrosine kinase inhibitor resistance - Homo sapiens (human); "]
["P62820","Ras-related protein Rab-1A OS=Homo sapiens OX=9606 GN=RAB1A","RAB1A",22.677,99.977,50.2,11,38,5,1.045,1.002,0.959,0.966,1.018,0.969,0.982,0.592,"cytoplasm\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:1905037 autophagosome organization; GO:0065008 regulation of biological quality; GO:0009914 hormone transport; GO:0032270 positive regulation of cellular protein metabolic process; GO:0035459 cargo loading into vesicle; GO:0048208 COPII vesicle coating; GO:0051443 positive regulation of ubiquitin-protein transferase activity; GO:0098542 defense response to other organism; GO:0032989 cellular component morphogenesis; GO:0006914 autophagy; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0009607 response to biotic stimulus; GO:0009605 response to external stimulus; GO:0022610 biological adhesion; GO:0051875 pigment granule localization; GO:0034446 substrate adhesion-dependent cell spreading; GO:0008152 metabolic process; GO:0065003 macromolecular complex assembly; GO:0044093 positive regulation of molecular function; GO:0032400 melanosome localization; GO:0048199 vesicle targeting, to, from or within Golgi; GO:0009306 protein secretion; GO:0007155 cell adhesion; GO:0051347 positive regulation of transferase activity; GO:0008104 protein localization; GO:0042886 amide transport; GO:0044419 interspecies interaction between organisms; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0002790 peptide secretion; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0007264 small GTPase mediated signal transduction; GO:0048870 cell motility; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0000902 cell morphogenesis; GO:0006810 transport; GO:0030072 peptide hormone secretion; GO:0007267 cell-cell signaling; GO:0007030 Golgi organization; GO:0050790 regulation of catalytic activity; GO:0098602 single organism cell adhesion; GO:0010604 positive regulation of macromolecule metabolic process; GO:0010817 regulation of hormone levels; GO:0000045 autophagosome assembly; GO:0050794 regulation of cellular process; GO:0051640 organelle localization; GO:0044707 single-multicellular organism process; GO:0046907 intracellular transport; GO:0031399 regulation of protein modification process; GO:0090110 cargo loading into COPII-coated vesicle; GO:0030252 growth hormone secretion; GO:0030705 cytoskeleton-dependent intracellular transport; GO:0009653 anatomical structure morphogenesis; GO:1902578 single-organism localization; GO:0072606 interleukin-8 secretion; GO:0051338 regulation of transferase activity; GO:0044248 cellular catabolic process; GO:1902580 single-organism cellular localization; GO:0009617 response to bacterium; GO:0006461 protein complex assembly; GO:0050663 cytokine secretion; GO:0006950 response to stress; GO:0090114 COPII-coated vesicle budding; GO:0016192 vesicle-mediated transport; GO:1903018 regulation of glycoprotein metabolic process; GO:0023061 signal release; GO:0071702 organic substance transport; GO:0051656 establishment of organelle localization; GO:0007017 microtubule-based process; GO:1904666 regulation of ubiquitin protein ligase activity; GO:0045184 establishment of protein localization; GO:0051247 positive regulation of protein metabolic process; GO:0051438 regulation of ubiquitin-protein transferase activity; GO:0031398 positive regulation of protein ubiquitination; GO:0001816 cytokine production; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0061024 membrane organization; GO:0006900 membrane budding; GO:1904668 positive regulation of ubiquitin protein ligase activity; GO:0043473 pigmentation; GO:0006928 movement of cell or subcellular component; GO:0051179 localization; GO:0033059 cellular pigmentation; GO:0006901 vesicle coating; GO:0010256 endomembrane system organization; GO:0048207 vesicle targeting, rough ER to cis-Golgi; GO:0051674 localization of cell; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0051668 localization within membrane; GO:0051234 establishment of localization; GO:0031396 regulation of protein ubiquitination; GO:0046879 hormone secretion; GO:0010970 transport along microtubule; GO:0007165 signal transduction; GO:1903020 positive regulation of glycoprotein metabolic process; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0009893 positive regulation of metabolic process; GO:0007033 vacuole organization; GO:0051904 pigment granule transport; GO:0033036 macromolecule localization; GO:0016236 macroautophagy; GO:0032502 developmental process; GO:0051650 establishment of vesicle localization; GO:0071822 protein complex subunit organization; GO:0048522 positive regulation of cellular process; GO:0032637 interleukin-8 production; GO:0023052 signaling; GO:1902582 single-organism intracellular transport; GO:0099518 vesicle cytoskeletal trafficking; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0032940 secretion by cell; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0006952 defense response; GO:0040011 locomotion; GO:0070271 protein complex biogenesis; GO:0015833 peptide transport; GO:0048856 anatomical structure development; GO:0072384 organelle transport along microtubule; GO:0016043 cellular component organization; GO:0016477 cell migration; GO:0019068 virion assembly; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0048193 Golgi vesicle transport; GO:0043207 response to external biotic stimulus; GO:0006903 vesicle targeting; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0099111 microtubule-based transport; GO:0048468 cell development; GO:0000904 cell morphogenesis involved in differentiation; GO:1903322 positive regulation of protein modification by small protein conjugation or removal; GO:0030154 cell differentiation; GO:0070925 organelle assembly; GO:0016032 viral process; GO:0051905 establishment of pigment granule localization; GO:0051648 vesicle localization; GO:0032402 melanosome transport; GO:0009987 cellular process; GO:0034622 cellular macromolecular complex assembly; GO:0035556 intracellular signal transduction; GO:0042742 defense response to bacterium; GO:0031401 positive regulation of protein modification process; GO:0016050 vesicle organization; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0047496 vesicle transport along microtubule; GO:0051641 cellular localization; GO:0043933 macromolecular complex subunit organization; GO:0007018 microtubule-based movement; GO:0006890 retrograde vesicle-mediated transport, Golgi to ER; GO:0031589 cell-substrate adhesion; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0032401 establishment of melanosome localization; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0009056 catabolic process; GO:0071705 nitrogen compound transport; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0030658 transport vesicle membrane; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0048770 pigment granule; GO:0005769 early endosome; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0042470 melanosome; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044432 endoplasmic reticulum part; GO:0005794 Golgi apparatus; GO:0030133 transport vesicle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0050839 cell adhesion molecule binding; GO:0097367 carbohydrate derivative binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0045296 cadherin binding; GO:0003924 GTPase activity; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019001 guanyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K07874","RAB1A; Ras-related protein Rab-1A","hsa05134 Legionellosis - Homo sapiens (human); ","IPR005225; IPR027417; ","Small GTP-binding protein domain; P-loop containing nucleoside triphosphate hydrolase; \r"]
["P62829","60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23","RPL23",14.865,61.302,37.9,4,11,4,0.767,0.841,0.825,1.18,1.237,1.199,1.486,0.000221,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0006518 peptide metabolic process; GO:0072594 establishment of protein localization to organelle; GO:0017038 protein import; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0051169 nuclear transport; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0051649 establishment of localization in cell; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0070972 protein localization to endoplasmic reticulum; GO:0006364 rRNA processing; GO:0006413 translational initiation; GO:1901361 organic cyclic compound catabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0033365 protein localization to organelle; GO:0044419 interspecies interaction between organisms; GO:0006412 translation; GO:0006606 protein import into nucleus; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0044765 single-organism transport; GO:0016072 rRNA metabolic process; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0072657 protein localization to membrane; GO:0043043 peptide biosynthetic process; GO:0042254 ribosome biogenesis; GO:1901360 organic cyclic compound metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032774 RNA biosynthetic process; GO:0045047 protein targeting to ER; GO:0043603 cellular amide metabolic process; GO:0006610 ribosomal protein import into nucleus; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051704 multi-organism process; GO:1902582 single-organism intracellular transport; GO:0016070 RNA metabolic process; GO:0006401 RNA catabolic process; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006913 nucleocytoplasmic transport; GO:0019083 viral transcription; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0046907 intracellular transport; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:1902593 single-organism nuclear import; GO:0044267 cellular protein metabolic process; GO:0006613 cotranslational protein targeting to membrane; GO:0048519 negative regulation of biological process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0016032 viral process; GO:0019080 viral gene expression; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0006886 intracellular protein transport; GO:0044744 protein targeting to nucleus; GO:0044248 cellular catabolic process; GO:1902580 single-organism cellular localization; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0009059 macromolecule biosynthetic process; GO:0034613 cellular protein localization; GO:0090150 establishment of protein localization to membrane; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0051170 nuclear import; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0051179 localization; GO:0034660 ncRNA metabolic process; GO:0009056 catabolic process; GO:0034504 protein localization to nucleus; GO:1901564 organonitrogen compound metabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:0046700 heterocycle catabolic process; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0005925 focal adhesion; GO:0070013 intracellular organelle lumen; GO:0044391 ribosomal subunit; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030055 cell-substrate junction; GO:0044445 cytosolic part; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0022626 cytosolic ribosome; GO:0043229 intracellular organelle; GO:0005840 ribosome; GO:0043232 intracellular non-membrane-bounded organelle; GO:0022625 cytosolic large ribosomal subunit; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0031012 extracellular matrix; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0015934 large ribosomal subunit; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0005198 structural molecule activity; GO:0003735 structural constituent of ribosome; GO:0070180 large ribosomal subunit rRNA binding; GO:0019843 rRNA binding; ","K02894","RP-L23e; large subunit ribosomal protein L23e","hsa03010 Ribosome - Homo sapiens (human); "]
["P62851","40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25","RPS25",13.742,9.0345,31.2,4,10,4,0.918,0.949,0.905,1.098,1.066,1.035,1.154,0.00292,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0072594 establishment of protein localization to organelle; GO:0006518 peptide metabolic process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0051649 establishment of localization in cell; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0070972 protein localization to endoplasmic reticulum; GO:0006364 rRNA processing; GO:0006413 translational initiation; GO:1901361 organic cyclic compound catabolic process; GO:0033365 protein localization to organelle; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0006412 translation; GO:0016072 rRNA metabolic process; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0072657 protein localization to membrane; GO:0043043 peptide biosynthetic process; GO:0042254 ribosome biogenesis; GO:1901360 organic cyclic compound metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032774 RNA biosynthetic process; GO:0045047 protein targeting to ER; GO:0043603 cellular amide metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0006401 RNA catabolic process; GO:0016070 RNA metabolic process; GO:0019439 aromatic compound catabolic process; GO:1901575 organic substance catabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0019083 viral transcription; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0046907 intracellular transport; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0044267 cellular protein metabolic process; GO:0006613 cotranslational protein targeting to membrane; GO:0048519 negative regulation of biological process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0016032 viral process; GO:0019080 viral gene expression; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0006886 intracellular protein transport; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0034613 cellular protein localization; GO:0009059 macromolecule biosynthetic process; GO:0090150 establishment of protein localization to membrane; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0051179 localization; GO:0009056 catabolic process; GO:0034660 ncRNA metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0015935 small ribosomal subunit; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044391 ribosomal subunit; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0044445 cytosolic part; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0022626 cytosolic ribosome; GO:0043229 intracellular organelle; GO:0005840 ribosome; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0031012 extracellular matrix; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0022627 cytosolic small ribosomal subunit; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005515 protein binding; GO:0005488 binding; GO:0003676 nucleic acid binding; ","K02975","RP-S25e; small subunit ribosomal protein S25e","hsa03010 Ribosome - Homo sapiens (human); "]
["P62873","Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 OS=Homo sapiens OX=9606 GN=GNB1","GNB1",37.377,107.4,34.4,10,27,4,1.052,1.091,1.11,0.905,0.908,0.907,0.836,0.00778,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0007596 blood coagulation; GO:0007166 cell surface receptor signaling pathway; GO:0050877 neurological system process; GO:0009605 response to external stimulus; GO:0065003 macromolecular complex assembly; GO:0010658 striated muscle cell apoptotic process; GO:0051606 detection of stimulus; GO:0055065 metal ion homeostasis; GO:0009719 response to endogenous stimulus; GO:0016055 Wnt signaling pathway; GO:1901652 response to peptide; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0009583 detection of light stimulus; GO:0071868 cellular response to monoamine stimulus; GO:0071214 cellular response to abiotic stimulus; GO:0030168 platelet activation; GO:0060359 response to ammonium ion; GO:0007212 dopamine receptor signaling pathway; GO:0071398 cellular response to fatty acid; GO:0044763 single-organism cellular process; GO:0007264 small GTPase mediated signal transduction; GO:0071242 cellular response to ammonium ion; GO:0032501 multicellular organismal process; GO:0006874 cellular calcium ion homeostasis; GO:0071396 cellular response to lipid; GO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway; GO:0051291 protein heterooligomerization; GO:0071482 cellular response to light stimulus; GO:0048513 animal organ development; GO:0010243 response to organonitrogen compound; GO:0007267 cell-cell signaling; GO:1901698 response to nitrogen compound; GO:0050817 coagulation; GO:1905144 response to acetylcholine; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0033554 cellular response to stress; GO:0009581 detection of external stimulus; GO:0009628 response to abiotic stimulus; GO:1901700 response to oxygen-containing compound; GO:0051259 protein oligomerization; GO:0001654 eye development; GO:0071229 cellular response to acid chemical; GO:0070482 response to oxygen levels; GO:0007275 multicellular organism development; GO:0009584 detection of visible light; GO:0070542 response to fatty acid; GO:0048878 chemical homeostasis; GO:0006461 protein complex assembly; GO:0071456 cellular response to hypoxia; GO:1901655 cellular response to ketone; GO:0006950 response to stress; GO:0009416 response to light stimulus; GO:0048731 system development; GO:0034694 response to prostaglandin; GO:0009582 detection of abiotic stimulus; GO:0071407 cellular response to organic cyclic compound; GO:0008283 cell proliferation; GO:0010033 response to organic substance; GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway; GO:0007186 G-protein coupled receptor signaling pathway; GO:0006873 cellular ion homeostasis; GO:0071870 cellular response to catecholamine stimulus; GO:0095500 acetylcholine receptor signaling pathway; GO:0001775 cell activation; GO:0007603 phototransduction, visible light; GO:0036293 response to decreased oxygen levels; GO:0012501 programmed cell death; GO:0033762 response to glucagon; GO:0007204 positive regulation of cytosolic calcium ion concentration; GO:0007423 sensory organ development; GO:0071379 cellular response to prostaglandin stimulus; GO:0016056 rhodopsin mediated signaling pathway; GO:0010659 cardiac muscle cell apoptotic process; GO:0001101 response to acid chemical; GO:0072503 cellular divalent inorganic cation homeostasis; GO:0034695 response to prostaglandin E; GO:0044699 single-organism process; GO:0010657 muscle cell apoptotic process; GO:0006457 protein folding; GO:0009611 response to wounding; GO:0035567 non-canonical Wnt signaling pathway; GO:0007213 G-protein coupled acetylcholine receptor signaling pathway; GO:0007165 signal transduction; GO:0007154 cell communication; GO:1901653 cellular response to peptide; GO:0022607 cellular component assembly; GO:0006915 apoptotic process; GO:0009314 response to radiation; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway; GO:0071869 response to catecholamine; GO:0007600 sensory perception; GO:0071822 protein complex subunit organization; GO:0050801 ion homeostasis; GO:0055074 calcium ion homeostasis; GO:0098771 inorganic ion homeostasis; GO:0019725 cellular homeostasis; GO:1905145 cellular response to acetylcholine; GO:0007223 Wnt signaling pathway, calcium modulating pathway; GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway; GO:0023052 signaling; GO:0198738 cell-cell signaling by wnt; GO:0071417 cellular response to organonitrogen compound; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0043434 response to peptide hormone; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:1901699 cellular response to nitrogen compound; GO:0032870 cellular response to hormone stimulus; GO:1903831 signal transduction involved in cellular response to ammonium ion; GO:0070271 protein complex biogenesis; GO:0072507 divalent inorganic cation homeostasis; GO:0048856 anatomical structure development; GO:0007265 Ras protein signal transduction; GO:0016043 cellular component organization; GO:0043010 camera-type eye development; GO:0030003 cellular cation homeostasis; GO:0051480 regulation of cytosolic calcium ion concentration; GO:0071310 cellular response to organic substance; GO:0071867 response to monoamine; GO:0050896 response to stimulus; GO:0055082 cellular chemical homeostasis; GO:0007599 hemostasis; GO:0050909 sensory perception of taste; GO:0042592 homeostatic process; GO:0071377 cellular response to glucagon stimulus; GO:0033993 response to lipid; GO:0055080 cation homeostasis; GO:0071375 cellular response to peptide hormone stimulus; GO:0007606 sensory perception of chemical stimulus; GO:0001666 response to hypoxia; GO:0071380 cellular response to prostaglandin E stimulus; GO:0071453 cellular response to oxygen levels; GO:0009987 cellular process; GO:0071478 cellular response to radiation; GO:0060041 retina development in camera-type eye; GO:0003008 system process; GO:0050878 regulation of body fluid levels; GO:0070206 protein trimerization; GO:0035556 intracellular signal transduction; GO:0007602 phototransduction; GO:0070208 protein heterotrimerization; GO:0043933 macromolecular complex subunit organization; GO:1901701 cellular response to oxygen-containing compound; GO:0042060 wound healing; GO:0008219 cell death; GO:0071495 cellular response to endogenous stimulus; GO:0044767 single-organism developmental process; GO:0006875 cellular metal ion homeostasis; GO:0009725 response to hormone; GO:0036294 cellular response to decreased oxygen levels; GO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; GO:0065007 biological regulation; GO:1901654 response to ketone; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0030425 dendrite; GO:0044421 extracellular region part; GO:0019898 extrinsic component of membrane; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0005623 cell; GO:0009898 cytoplasmic side of plasma membrane; GO:0044422 organelle part; GO:0005765 lysosomal membrane; GO:0070062 extracellular exosome; GO:0098590 plasma membrane region; GO:0001917 photoreceptor inner segment; GO:0043209 myelin sheath; GO:0005622 intracellular; GO:0005764 lysosome; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0098552 side of membrane; GO:0000323 lytic vacuole; GO:0005929 cilium; GO:1905360 GTPase complex; GO:0042995 cell projection; GO:0098797 plasma membrane protein complex; GO:0019897 extrinsic component of plasma membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0097733 photoreceptor cell cilium; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0060170 ciliary membrane; GO:0098796 membrane protein complex; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0097730 non-motile cilium; GO:0044424 intracellular part; GO:0031234 extrinsic component of cytoplasmic side of plasma membrane; GO:0098562 cytoplasmic side of membrane; GO:0097731 9+0 non-motile cilium; GO:1902494 catalytic complex; GO:0005834 heterotrimeric G-protein complex; GO:0044441 ciliary part; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0001750 photoreceptor outer segment; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0044463 cell projection part; GO:0005829 cytosol; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0097381 photoreceptor disc membrane; GO:0044459 plasma membrane part; GO:0031253 cell projection membrane; GO:0005774 vacuolar membrane; GO:0044297 cell body; GO:0042622 photoreceptor outer segment membrane; GO:0044444 cytoplasmic part; ","GO:0005102 receptor binding; GO:0044877 macromolecular complex binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0017111 nucleoside-triphosphatase activity; GO:0004871 signal transducer activity; GO:0030507 spectrin binding; GO:0008092 cytoskeletal protein binding; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0042578 phosphoric ester hydrolase activity; GO:0005488 binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0003924 GTPase activity; GO:0031702 type 1 angiotensin receptor binding; GO:0001664 G-protein coupled receptor binding; GO:0008081 phosphoric diester hydrolase activity; GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity; GO:0051020 GTPase binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0031701 angiotensin receptor binding; GO:0019899 enzyme binding; GO:0032403 protein complex binding; ","K04536","GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1","hsa04728 Dopaminergic synapse - Homo sapiens (human); hsa04371 Apelin signaling pathway - Homo sapiens (human); hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human); hsa04014 Ras signaling pathway - Homo sapiens (human); hsa05167 Kaposi's sarcoma-associated herpesvirus infection - Homo sapiens (human); hsa04726 Serotonergic synapse - Homo sapiens (human); hsa04724 Glutamatergic synapse - Homo sapiens (human); hsa04062 Chemokine signaling pathway - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa04740 Olfactory transduction - Homo sapiens (human); hsa04727 GABAergic synapse - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa05034 Alcoholism - Homo sapiens (human); hsa04926 Relaxin signaling pathway - Homo sapiens (human); hsa04713 Circadian entrainment - Homo sapiens (human); hsa04744 Phototransduction - Homo sapiens (human); hsa04725 Cholinergic synapse - Homo sapiens (human); hsa05032 Morphine addiction - Homo sapiens (human); ","IPR017986; IPR015943; IPR001632; ","\"WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain; G-protein, beta subunit; \"\r"]
["P62879","Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 OS=Homo sapiens OX=9606 GN=GNB2","GNB2",37.331,120.73,37.9,11,25,4,0.971,1.04,0.984,0.994,0.931,1.011,0.98,0.573,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0071310 cellular response to organic substance; GO:1901700 response to oxygen-containing compound; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0006457 protein folding; GO:0071377 cellular response to glucagon stimulus; GO:0007165 signal transduction; GO:1901653 cellular response to peptide; GO:0007154 cell communication; GO:0071375 cellular response to peptide hormone stimulus; GO:0009719 response to endogenous stimulus; GO:1901652 response to peptide; GO:0009987 cellular process; GO:0070887 cellular response to chemical stimulus; GO:0051716 cellular response to stimulus; GO:0010033 response to organic substance; GO:0023052 signaling; GO:0071417 cellular response to organonitrogen compound; GO:0007186 G-protein coupled receptor signaling pathway; GO:0010243 response to organonitrogen compound; GO:0050789 regulation of biological process; GO:1901701 cellular response to oxygen-containing compound; GO:0042221 response to chemical; GO:0043434 response to peptide hormone; GO:1901699 cellular response to nitrogen compound; GO:0071495 cellular response to endogenous stimulus; GO:0032870 cellular response to hormone stimulus; GO:1901698 response to nitrogen compound; GO:0065009 regulation of molecular function; GO:0033762 response to glucagon; GO:0009725 response to hormone; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005765 lysosomal membrane; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0043209 myelin sheath; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005764 lysosome; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0044297 cell body; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0044877 macromolecular complex binding; GO:0099106 ion channel regulator activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0017111 nucleoside-triphosphatase activity; GO:0098772 molecular function regulator; GO:0005246 calcium channel regulator activity; GO:0004871 signal transducer activity; GO:0016462 pyrophosphatase activity; GO:0016247 channel regulator activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0003924 GTPase activity; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0051020 GTPase binding; GO:0019899 enzyme binding; GO:0032403 protein complex binding; ","K04537","GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2","hsa05200 Pathways in cancer - Homo sapiens (human); hsa04728 Dopaminergic synapse - Homo sapiens (human); hsa04371 Apelin signaling pathway - Homo sapiens (human); hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human); hsa04727 GABAergic synapse - Homo sapiens (human); hsa04014 Ras signaling pathway - Homo sapiens (human); hsa05167 Kaposi's sarcoma-associated herpesvirus infection - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa05034 Alcoholism - Homo sapiens (human); hsa04726 Serotonergic synapse - Homo sapiens (human); hsa04713 Circadian entrainment - Homo sapiens (human); hsa04724 Glutamatergic synapse - Homo sapiens (human); hsa04926 Relaxin signaling pathway - Homo sapiens (human); hsa05032 Morphine addiction - Homo sapiens (human); hsa04725 Cholinergic synapse - Homo sapiens (human); hsa04062 Chemokine signaling pathway - Homo sapiens (human); ","IPR017986; IPR015943; IPR001632; ","\"WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain; G-protein, beta subunit; \"\r"]
["P62888","60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30","RPL30",12.784,43.381,50.4,5,10,5,0.911,0.966,0.92,1.065,1.07,1.058,1.142,0.00196,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0032270 positive regulation of cellular protein metabolic process; GO:0006518 peptide metabolic process; GO:0048732 gland development; GO:0010608 posttranscriptional regulation of gene expression; GO:0009891 positive regulation of biosynthetic process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0070972 protein localization to endoplasmic reticulum; GO:0006364 rRNA processing; GO:0033365 protein localization to organelle; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:1904571 positive regulation of selenocysteine incorporation; GO:0008104 protein localization; GO:0006396 RNA processing; GO:0018130 heterocycle biosynthetic process; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0072657 protein localization to membrane; GO:0080090 regulation of primary metabolic process; GO:0042254 ribosome biogenesis; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032774 RNA biosynthetic process; GO:0045047 protein targeting to ER; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0048513 animal organ development; GO:0006402 mRNA catabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0044707 single-multicellular organism process; GO:0044267 cellular protein metabolic process; GO:0048519 negative regulation of biological process; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0051171 regulation of nitrogen compound metabolic process; GO:0044248 cellular catabolic process; GO:0061008 hepaticobiliary system development; GO:0007275 multicellular organism development; GO:0034655 nucleobase-containing compound catabolic process; GO:0034613 cellular protein localization; GO:0090150 establishment of protein localization to membrane; GO:0048731 system development; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0034248 regulation of cellular amide metabolic process; GO:0045184 establishment of protein localization; GO:0001889 liver development; GO:0051247 positive regulation of protein metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0051179 localization; GO:0045901 positive regulation of translational elongation; GO:1901564 organonitrogen compound metabolic process; GO:0031100 animal organ regeneration; GO:0072594 establishment of protein localization to organelle; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0051649 establishment of localization in cell; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0006413 translational initiation; GO:1901361 organic cyclic compound catabolic process; GO:0006412 translation; GO:0033036 macromolecule localization; GO:0032502 developmental process; GO:0034470 ncRNA processing; GO:0016072 rRNA metabolic process; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0045727 positive regulation of translation; GO:0043043 peptide biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0043603 cellular amide metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0006401 RNA catabolic process; GO:0016070 RNA metabolic process; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0090304 nucleic acid metabolic process; GO:0019222 regulation of metabolic process; GO:0019083 viral transcription; GO:0048856 anatomical structure development; GO:0097421 liver regeneration; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0006613 cotranslational protein targeting to membrane; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0016032 viral process; GO:0019080 viral gene expression; GO:0006886 intracellular protein transport; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:1904569 regulation of selenocysteine incorporation; GO:0006448 regulation of translational elongation; GO:0010629 negative regulation of gene expression; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0070727 cellular macromolecule localization; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0006417 regulation of translation; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0009057 macromolecule catabolic process; GO:0034250 positive regulation of cellular amide metabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0031099 regeneration; GO:0034660 ncRNA metabolic process; GO:0009056 catabolic process; GO:0065007 biological regulation; GO:0046700 heterocycle catabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0044391 ribosomal subunit; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030055 cell-substrate junction; GO:0044445 cytosolic part; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0022626 cytosolic ribosome; GO:0043229 intracellular organelle; GO:0005840 ribosome; GO:0043232 intracellular non-membrane-bounded organelle; GO:0022625 cytosolic large ribosomal subunit; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031012 extracellular matrix; GO:0005634 nucleus; GO:0015934 large ribosomal subunit; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0035368 selenocysteine insertion sequence binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0003729 mRNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0003735 structural constituent of ribosome; GO:0005198 structural molecule activity; ","K02908","RP-L30e; large subunit ribosomal protein L30e","hsa03010 Ribosome - Homo sapiens (human); ","IPR029064; IPR004038; ","50S ribosomal protein L30e-like; Ribosomal protein L7Ae/L30e/S12e/Gadd45; \r"]
["P62913","60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11","RPL11",20.252,28.019,30.3,7,15,7,0.876,0.871,0.919,1.125,1.138,1.1,1.261,0.000298,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0006518 peptide metabolic process; GO:0072594 establishment of protein localization to organelle; GO:0022618 ribonucleoprotein complex assembly; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0042273 ribosomal large subunit biogenesis; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0051649 establishment of localization in cell; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0071826 ribonucleoprotein complex subunit organization; GO:0000027 ribosomal large subunit assembly; GO:0070972 protein localization to endoplasmic reticulum; GO:0022607 cellular component assembly; GO:0006364 rRNA processing; GO:0065003 macromolecular complex assembly; GO:0006413 translational initiation; GO:1901361 organic cyclic compound catabolic process; GO:0019538 protein metabolic process; GO:0033365 protein localization to organelle; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0006412 translation; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0016072 rRNA metabolic process; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0072657 protein localization to membrane; GO:0043043 peptide biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0042254 ribosome biogenesis; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032774 RNA biosynthetic process; GO:0045047 protein targeting to ER; GO:0043603 cellular amide metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051704 multi-organism process; GO:0016070 RNA metabolic process; GO:0006401 RNA catabolic process; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0019083 viral transcription; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0044267 cellular protein metabolic process; GO:0006613 cotranslational protein targeting to membrane; GO:0048519 negative regulation of biological process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0070925 organelle assembly; GO:0006139 nucleobase-containing compound metabolic process; GO:0016032 viral process; GO:0019080 viral gene expression; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0006886 intracellular protein transport; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0009059 macromolecule biosynthetic process; GO:0034613 cellular protein localization; GO:0090150 establishment of protein localization to membrane; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0034622 cellular macromolecular complex assembly; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0042255 ribosome assembly; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006996 organelle organization; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0051179 localization; GO:0034504 protein localization to nucleus; GO:0034660 ncRNA metabolic process; GO:0009056 catabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; GO:0046700 heterocycle catabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044391 ribosomal subunit; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0044445 cytosolic part; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0022626 cytosolic ribosome; GO:0043229 intracellular organelle; GO:0005840 ribosome; GO:0043232 intracellular non-membrane-bounded organelle; GO:0022625 cytosolic large ribosomal subunit; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0031012 extracellular matrix; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0015934 large ribosomal subunit; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0005198 structural molecule activity; GO:0003735 structural constituent of ribosome; GO:0019843 rRNA binding; ","K02868","RP-L11e; large subunit ribosomal protein L11e","hsa03010 Ribosome - Homo sapiens (human); ","IPR022803; IPR031309; IPR031310; ","\"Ribosomal protein L5 domain; Ribosomal protein L5, C-terminal; Ribosomal protein L5, N-terminal; \"\r"]
["P62917","60S ribosomal protein L8 OS=Homo sapiens OX=9606 GN=RPL8","RPL8",28.024,29.281,33.9,7,11,7,0.836,0.878,0.92,1.095,1.126,1.076,1.252,1.82E-3,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0072594 establishment of protein localization to organelle; GO:0006518 peptide metabolic process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0071363 cellular response to growth factor stimulus; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0051649 establishment of localization in cell; GO:0002181 cytoplasmic translation; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0070972 protein localization to endoplasmic reticulum; GO:0006364 rRNA processing; GO:0006413 translational initiation; GO:1901361 organic cyclic compound catabolic process; GO:0009719 response to endogenous stimulus; GO:0070848 response to growth factor; GO:0033365 protein localization to organelle; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0006412 translation; GO:0070887 cellular response to chemical stimulus; GO:0016072 rRNA metabolic process; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0051716 cellular response to stimulus; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0072657 protein localization to membrane; GO:0043043 peptide biosynthetic process; GO:0042254 ribosome biogenesis; GO:1901360 organic cyclic compound metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032774 RNA biosynthetic process; GO:0045047 protein targeting to ER; GO:0043603 cellular amide metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0016070 RNA metabolic process; GO:0006401 RNA catabolic process; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0090304 nucleic acid metabolic process; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0019083 viral transcription; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0046907 intracellular transport; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0071310 cellular response to organic substance; GO:0044267 cellular protein metabolic process; GO:0006613 cotranslational protein targeting to membrane; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0016032 viral process; GO:0019080 viral gene expression; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0006886 intracellular protein transport; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0034613 cellular protein localization; GO:0009059 macromolecule biosynthetic process; GO:0090150 establishment of protein localization to membrane; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:1990089 response to nerve growth factor; GO:0010629 negative regulation of gene expression; GO:1990090 cellular response to nerve growth factor stimulus; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0071495 cellular response to endogenous stimulus; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0051179 localization; GO:0034660 ncRNA metabolic process; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; GO:1901564 organonitrogen compound metabolic process; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; ","GO:0005840 ribosome; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0043232 intracellular non-membrane-bounded organelle; GO:0030054 cell junction; GO:0022625 cytosolic large ribosomal subunit; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0070161 anchoring junction; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0005925 focal adhesion; GO:0015934 large ribosomal subunit; GO:0044391 ribosomal subunit; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:0030055 cell-substrate junction; GO:0044445 cytosolic part; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0005924 cell-substrate adherens junction; GO:0044444 cytoplasmic part; GO:0022626 cytosolic ribosome; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:1990932 5.8S rRNA binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005198 structural molecule activity; GO:0003735 structural constituent of ribosome; GO:0019843 rRNA binding; ","K02938","RP-L8e; large subunit ribosomal protein L8e","hsa03010 Ribosome - Homo sapiens (human); ","IPR008991; IPR012340; IPR022669; IPR014726; IPR022666; IPR014722; ","\"Translation protein SH3-like domain; Nucleic acid-binding, OB-fold; Ribosomal protein L2, C-terminal; Ribosomal protein L2, domain 3; Ribosomal Proteins L2, RNA binding domain; Ribosomal protein L2 domain 2; \"\r"]
["P62979","Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A","RPS27A",17.965,132.63,42.3,6,35,6,0.943,0.957,1.002,1.026,1.028,1.042,1.067,0.0263,"extracellular\r",{"$cut":{"chars":28521,"head":"GO:0044700 single organism signaling; GO:0036508 protein alpha-1,2-demannosylation; GO:0010608 posttranscriptional regulation of gene expression; GO:1901185 negative regulation of ERBB signaling pathway; GO:0051443 positive regulation of ubiquitin-protein transferase activity; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0044264 cellular polysaccharide metabolic process; GO:0072431 signal transduction involved in mitotic G1 DNA damage checkpoint; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0044033 multi-organism metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0070972 protein localization to endoplasmic reticulum; GO:0044770 cell cycle phase transition; GO:0006396 RNA processing; GO:0080090 regulation of primary metabolic process; GO:0010972 negative regulation of G2/M transition of mitotic cell cycle; GO:2000134 negative regulation of G1/S transition of mitotic cell cycle; GO:0060828 regulation of canonical Wnt signaling pathway; GO:0090287 regulation of cellular response to growth factor stimulus; GO:0071559 response to transforming growth factor beta; GO:0005975 carbohydrate metabolic process; GO:0033209 tumor necrosis factor-mediated signaling pathway; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0051092 positive regulation of NF-kappaB transcription factor activity; GO:1902400 intracellular signal transduction involved in G1 DNA damage checkpoint; GO:0006402 mRNA catabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0060071 Wnt signaling pathway, planar cell polarity pathway; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0090305 nucleic acid phosphodiester bond hydrolysis; GO:0060548 negative regulation of cell death; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0016310 phosphorylation; GO:0006259 DNA metabolic process; GO:0051806 entry into cell of other organism involved in symbiotic interaction; GO:0044042 glucan metabolic process; GO:0043487 regulation of RNA stability; GO:0045892 negative regulation of transcription, DNA-templated; GO:0044270 cellular nitrogen compound catabolic process; GO:0023057 negative regulation of signaling; GO:0046483 heterocycle metabolic process; GO:0010648 negative regulation of cell communication; GO:0006139 nucleobase-containing compound metabolic process; GO:1902402 signal transduction involved in mitotic DNA damage checkpoint; GO:0009889 regulation of biosynthetic process; GO:0044819 mitotic G1/S transition checkpoint; GO:0009896 positive regulation of catabolic process; GO:0044248 cellular catabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0038093 Fc receptor signaling pathway; GO:0023014 signal transduction by protein phosphorylation; GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; GO:0044711 single-organism biosynthetic process; GO:0072331 signal transduction by p53 class mediator; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress; GO:0006974 cellular response to DNA damage stimulus; GO:1903321 negative regulation of protein modification by small protein conjugation or removal; GO:0044766 multi-organism transport; GO:0006294 nucleotide-excision repair, preincision complex assembly; GO:0044839 cell cycle G2/M phase transition; GO:0006955 immune response; GO:0043412 macromolecule modification; GO:2000045 regulation of G1/S transition of mitotic cell cycle; GO:0070646 protein modification by small protein removal; GO:0072594 establishment of protein localization to organelle; GO:0031331 positive regulation of cellular catabolic process; GO:0051253 negative regulation of RNA metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0006612 protein targeting to membrane; GO:0045930 negative regulation of mitoti"}},"GO:0016020 membrane; GO:0019867 outer membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0015935 small ribosomal subunit; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0043209 myelin sheath; GO:0005622 intracellular; GO:0044322 endoplasmic reticulum quality control compartment; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0022626 cytosolic ribosome; GO:0010008 endosome membrane; GO:0005840 ribosome; GO:0030666 endocytic vesicle membrane; GO:0031967 organelle envelope; GO:0012506 vesicle membrane; GO:0044440 endosomal part; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0031975 envelope; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0031966 mitochondrial membrane; GO:0043230 extracellular organelle; GO:0005783 endoplasmic reticulum; GO:0005615 extracellular space; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0031974 membrane-enclosed lumen; GO:0005740 mitochondrial envelope; GO:0070013 intracellular organelle lumen; GO:0044391 ribosomal subunit; GO:0044464 cell part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0031968 organelle outer membrane; GO:0044445 cytosolic part; GO:0030139 endocytic vesicle; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0044429 mitochondrial part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005741 mitochondrial outer membrane; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0005634 nucleus; GO:0044432 endoplasmic reticulum part; GO:0022627 cytosolic small ribosomal subunit; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0043167 ion binding; GO:0003676 nucleic acid binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0005198 structural molecule activity; GO:0003735 structural constituent of ribosome; ","K02977","RP-S27Ae; small subunit ribosomal protein S27Ae","hsa03010 Ribosome - Homo sapiens (human); ","IPR002906; IPR011332; IPR029071; IPR000626; ","Ribosomal protein S27a; Zinc-binding ribosomal protein; Ubiquitin-related domain; Ubiquitin domain; \r"]
["P62995","Transformer-2 protein homolog beta OS=Homo sapiens OX=9606 GN=TRA2B","TRA2B",33.665,11.385,14.2,4,4,4,0.91,0.87,0.893,1.033,1.132,1.153,1.241,0.0041,"nucleus\r","GO:0000381 regulation of alternative mRNA splicing, via spliceosome; GO:0007420 brain development; GO:0050686 negative regulation of mRNA processing; GO:0044699 single-organism process; GO:0021987 cerebral cortex development; GO:0051253 negative regulation of RNA metabolic process; GO:1903312 negative regulation of mRNA metabolic process; GO:0044237 cellular metabolic process; GO:0021537 telencephalon development; GO:0008152 metabolic process; GO:0021796 cerebral cortex regionalization; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0006979 response to oxidative stress; GO:0060322 head development; GO:0043170 macromolecule metabolic process; GO:0009790 embryo development; GO:0048024 regulation of mRNA splicing, via spliceosome; GO:0007399 nervous system development; GO:0006396 RNA processing; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0080090 regulation of primary metabolic process; GO:0021978 telencephalon regionalization; GO:0000302 response to reactive oxygen species; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0050684 regulation of mRNA processing; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0032501 multicellular organismal process; GO:1903313 positive regulation of mRNA metabolic process; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0090304 nucleic acid metabolic process; GO:0007417 central nervous system development; GO:0021871 forebrain regionalization; GO:0044260 cellular macromolecule metabolic process; GO:0033119 negative regulation of RNA splicing; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0016071 mRNA metabolic process; GO:0048856 anatomical structure development; GO:0033120 positive regulation of RNA splicing; GO:0050794 regulation of cellular process; GO:0021543 pallium development; GO:0044707 single-multicellular organism process; GO:0050685 positive regulation of mRNA processing; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0048568 embryonic organ development; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:1901700 response to oxygen-containing compound; GO:0007389 pattern specification process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:1990403 embryonic brain development; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0010628 positive regulation of gene expression; GO:0000375 RNA splicing, via transesterification reactions; GO:0051171 regulation of nitrogen compound metabolic process; GO:0030900 forebrain development; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0008380 RNA splicing; GO:0051254 positive regulation of RNA metabolic process; GO:0006950 response to stress; GO:0003002 regionalization; GO:0010629 negative regulation of gene expression; GO:0048731 system development; GO:0006807 nitrogen compound metabolic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0043484 regulation of RNA splicing; GO:1903311 regulation of mRNA metabolic process; GO:0044767 single-organism developmental process; GO:0031325 positive regulation of cellular metabolic process; GO:0048026 positive regulation of mRNA splicing, via spliceosome; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0010467 gene expression; GO:0048025 negative regulation of mRNA splicing, via spliceosome; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0043229 intracellular organelle; GO:0031090 organelle membrane; GO:0005635 nuclear envelope; GO:0031967 organelle envelope; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031974 membrane-enclosed lumen; GO:0031965 nuclear membrane; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0031975 envelope; GO:0019866 organelle inner membrane; GO:0048471 perinuclear region of cytoplasm; GO:0043227 membrane-bounded organelle; GO:0005637 nuclear inner membrane; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003729 mRNA binding; GO:0003723 RNA binding; GO:1901265 nucleoside phosphate binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0036002 pre-mRNA binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0070717 poly-purine tract binding; GO:0036094 small molecule binding; GO:0003727 single-stranded RNA binding; ","K12897","TRA2; transformer-2 protein","hsa03040 Spliceosome - Homo sapiens (human); ","IPR000504; IPR012677; ","RNA recognition motif domain; Nucleotide-binding alpha-beta plait domain; \r"]
["P63096","Guanine nucleotide-binding protein G(i) subunit alpha-1 OS=Homo sapiens OX=9606 GN=GNAI1","GNAI1",40.361,2.2973,22,8,17,1,1.001,1.082,1.029,0.965,0.92,1.016,0.932,0.126,"cytoplasm\r","GO:0044700 single organism signaling; GO:0050794 regulation of cellular process; GO:0043949 regulation of cAMP-mediated signaling; GO:0071310 cellular response to organic substance; GO:0023051 regulation of signaling; GO:1901700 response to oxygen-containing compound; GO:0044699 single-organism process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:0006457 protein folding; GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; GO:0033993 response to lipid; GO:0007165 signal transduction; GO:0023057 negative regulation of signaling; GO:0010646 regulation of cell communication; GO:0010648 negative regulation of cell communication; GO:0007154 cell communication; GO:0009719 response to endogenous stimulus; GO:1901652 response to peptide; GO:0009987 cellular process; GO:0009966 regulation of signal transduction; GO:0070887 cellular response to chemical stimulus; GO:0051716 cellular response to stimulus; GO:0014070 response to organic cyclic compound; GO:0050805 negative regulation of synaptic transmission; GO:1902531 regulation of intracellular signal transduction; GO:1901655 cellular response to ketone; GO:1904322 cellular response to forskolin; GO:1904321 response to forskolin; GO:0050804 modulation of synaptic transmission; GO:0044763 single-organism cellular process; GO:0071407 cellular response to organic cyclic compound; GO:0010033 response to organic substance; GO:0023052 signaling; GO:0071396 cellular response to lipid; GO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway; GO:0007186 G-protein coupled receptor signaling pathway; GO:0010243 response to organonitrogen compound; GO:1901701 cellular response to oxygen-containing compound; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0043434 response to peptide hormone; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0051301 cell division; GO:0009725 response to hormone; GO:0007049 cell cycle; GO:1901654 response to ketone; GO:0065007 biological regulation; GO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0019898 extrinsic component of membrane; GO:0031090 organelle membrane; GO:0098857 membrane microdomain; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0031234 extrinsic component of cytoplasmic side of plasma membrane; GO:0005623 cell; GO:0009898 cytoplasmic side of plasma membrane; GO:0098562 cytoplasmic side of membrane; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0005765 lysosomal membrane; GO:0070062 extracellular exosome; GO:1902494 catalytic complex; GO:0005815 microtubule organizing center; GO:0070013 intracellular organelle lumen; GO:0005834 heterotrimeric G-protein complex; GO:0015630 microtubule cytoskeleton; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005764 lysosome; GO:0098589 membrane region; GO:1903561 extracellular vesicle; GO:0045121 membrane raft; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0098552 side of membrane; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:1905360 GTPase complex; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0098797 plasma membrane protein complex; GO:0044446 intracellular organelle part; GO:0030496 midbody; GO:0019897 extrinsic component of plasma membrane; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0005813 centrosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0005102 receptor binding; GO:0031683 G-protein beta/gamma-subunit complex binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0004871 signal transducer activity; GO:0032794 GTPase activating protein binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0019003 GDP binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0003924 GTPase activity; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0001664 G-protein coupled receptor binding; GO:0043168 anion binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0017076 purine nucleotide binding; GO:0031821 G-protein coupled serotonin receptor binding; GO:0000287 magnesium ion binding; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0046872 metal ion binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0032561 guanyl ribonucleotide binding; GO:0032403 protein complex binding; GO:0036094 small molecule binding; ","K04630","GNAI; guanine nucleotide-binding protein G(i) subunit alpha","hsa04015 Rap1 signaling pathway - Homo sapiens (human); hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human); hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human); hsa04924 Renin secretion - Homo sapiens (human); hsa04724 Glutamatergic synapse - Homo sapiens (human); hsa05145 Toxoplasmosis - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa04934 Cushing's syndrome - Homo sapiens (human); hsa04071 Sphingolipid signaling pathway - Homo sapiens (human); hsa04611 Platelet activation - Homo sapiens (human); hsa05034 Alcoholism - Homo sapiens (human); hsa04971 Gastric acid secretion - Homo sapiens (human); hsa04914 Progesterone-mediated oocyte maturation - Homo sapiens (human); hsa04915 Estrogen signaling pathway - Homo sapiens (human); hsa05032 Morphine addiction - Homo sapiens (human); hsa04725 Cholinergic synapse - Homo sapiens (human); hsa04921 Oxytocin signaling pathway - Homo sapiens (human); hsa05142 Chagas disease (American trypanosomiasis) - Homo sapiens (human); hsa04728 Dopaminergic synapse - Homo sapiens (human); hsa04371 Apelin signaling pathway - Homo sapiens (human); hsa04916 Melanogenesis - Homo sapiens (human); hsa04923 Regulation of lipolysis in adipocytes - Homo sapiens (human); hsa04024 cAMP signaling pathway - Homo sapiens (human); hsa04670 Leukocyte transendothelial migration - Homo sapiens (human); hsa05030 Cocaine addiction - Homo sapiens (human); hsa04726 Serotonergic synapse - Homo sapiens (human); hsa04062 Chemokine signaling pathway - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human); hsa04540 Gap junction - Homo sapiens (human); hsa04727 GABAergic synapse - Homo sapiens (human); hsa04730 Long-term depression - Homo sapiens (human); hsa05133 Pertussis - Homo sapiens (human); hsa04360 Axon guidance - Homo sapiens (human); hsa04926 Relaxin signaling pathway - Homo sapiens (human); hsa04928 Parathyroid hormone synthesis, secretion and action - Homo sapiens (human); hsa04713 Circadian entrainment - Homo sapiens (human); ","IPR027417; IPR011025; ","\"P-loop containing nucleoside triphosphate hydrolase; G protein alpha subunit, helical insertion; \"\r"]
["P63098","Calcineurin subunit B type 1 OS=Homo sapiens OX=9606 GN=PPP3R1","PPP3R1",19.3,16.246,24.7,5,6,5,1.068,0.951,1.068,0.925,0.958,0.924,0.909,0.0814,"cytoplasm\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0010941 regulation of cell death; GO:0007272 ensheathment of neurons; GO:0007166 cell surface receptor signaling pathway; GO:0030323 respiratory tube development; GO:1903533 regulation of protein targeting; GO:0051532 regulation of NFAT protein import into nucleus; GO:0009891 positive regulation of biosynthetic process; GO:0014037 Schwann cell differentiation; GO:0051169 nuclear transport; GO:0010821 regulation of mitochondrion organization; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0014044 Schwann cell development; GO:0048754 branching morphogenesis of an epithelial tube; GO:0001525 angiogenesis; GO:0008152 metabolic process; GO:0007507 heart development; GO:1901028 regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; GO:0097720 calcineurin-mediated signaling; GO:1903747 regulation of establishment of protein localization to mitochondrion; GO:0032879 regulation of localization; GO:0033365 protein localization to organelle; GO:0090559 regulation of membrane permeability; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006606 protein import into nucleus; GO:0008104 protein localization; GO:0016055 Wnt signaling pathway; GO:0001569 branching involved in blood vessel morphogenesis; GO:0007422 peripheral nervous system development; GO:0044765 single-organism transport; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0035239 tube morphogenesis; GO:0001763 morphogenesis of a branching structure; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044763 single-organism cellular process; GO:0019932 second-messenger-mediated signaling; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0042552 myelination; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0042063 gliogenesis; GO:0007267 cell-cell signaling; GO:0042991 transcription factor import into nucleus; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006913 nucleocytoplasmic transport; GO:0002682 regulation of immune system process; GO:0006464 cellular protein modification process; GO:0051223 regulation of protein transport; GO:0043068 positive regulation of programmed cell death; GO:0030855 epithelial cell differentiation; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0042307 positive regulation of protein import into nucleus; GO:0072359 circulatory system development; GO:0050794 regulation of cellular process; GO:0002009 morphogenesis of an epithelium; GO:0046907 intracellular transport; GO:0044707 single-multicellular organism process; GO:0007006 mitochondrial membrane organization; GO:1902593 single-organism nuclear import; GO:0043067 regulation of programmed cell death; GO:0044267 cellular protein metabolic process; GO:1905477 positive regulation of protein localization to membrane; GO:0042990 regulation of transcription factor import into nucleus; GO:0060341 regulation of cellular localization; GO:0009653 anatomical structure morphogenesis; GO:1900740 positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; GO:0060428 lung epithelium development; GO:1902578 single-organism localization; GO:0019722 calcium-mediated signaling; GO:0060541 respiratory system development; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0060479 lung cell differentiation; GO:0051171 regulation of nitrogen compound metabolic process; GO:0044744 protein targeting to nucleus; GO:1902680 positive regulation of RNA biosynthetic process; GO:1902580 single-organism cellular localization; GO:1901030 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; GO:0007275 multicellular organism development; GO:0032880 regulation of protein localization; GO:0034613 cellular protein localization; GO:0038093 Fc receptor signaling pathway; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0009966 regulation of signal transduction; GO:0060562 epithelial tube morphogenesis; GO:0051254 positive regulation of RNA metabolic process; GO:0060485 mesenchyme development; GO:0048731 system development; GO:0072358 cardiovascular system development; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0045184 establishment of protein localization; GO:1900182 positive regulation of protein localization to nucleus; GO:0061138 morphogenesis of a branching epithelium; GO:0046822 regulation of nucleocytoplasmic transport; GO:1904951 positive regulation of establishment of protein localization; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0061024 membrane organization; GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; GO:0051531 NFAT protein import into nucleus; GO:0031328 positive regulation of cellular biosynthetic process; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:0043412 macromolecule modification; GO:1903827 regulation of cellular protein localization; GO:1904591 positive regulation of protein import; GO:0051533 positive regulation of NFAT protein import into nucleus; GO:0072594 establishment of protein localization to organelle; GO:0001568 blood vessel development; GO:0017038 protein import; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:0006839 mitochondrial transport; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0033173 calcineurin-NFAT signaling cascade; GO:0001837 epithelial to mesenchymal transition; GO:0006796 phosphate-containing compound metabolic process; GO:1903749 positive regulation of establishment of protein localization to mitochondrion; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0035567 non-canonical Wnt signaling pathway; GO:0051130 positive regulation of cellular component organization; GO:2001141 regulation of RNA biosynthetic process; GO:2001233 regulation of apoptotic signaling pathway; GO:0048729 tissue morphogenesis; GO:0042306 regulation of protein import into nucleus; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0007005 mitochondrion organization; GO:0046824 positive regulation of nucleocytoplasmic transport; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0048514 blood vessel morphogenesis; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0033036 macromolecule localization; GO:0030324 lung development; GO:0032502 developmental process; GO:0035295 tube development; GO:0060429 epithelium development; GO:0010468 regulation of gene expression; GO:0009888 tissue development; GO:0031326 regulation of cellular biosynthetic process; GO:0001944 vasculature development; GO:0048522 positive regulation of cellular process; GO:0032386 regulation of intracellular transport; GO:0007223 Wnt signaling pathway, calcium modulating pathway; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:1902582 single-organism intracellular transport; GO:0010942 positive regulation of cell death; GO:0051050 positive regulation of transport; GO:0198738 cell-cell signaling by wnt; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0010638 positive regulation of organelle organization; GO:0032292 peripheral nervous system axon ensheathment; GO:1900180 regulation of protein localization to nucleus; GO:0021782 glial cell development; GO:0019222 regulation of metabolic process; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0051222 positive regulation of protein transport; GO:0016043 cellular component organization; GO:0090316 positive regulation of intracellular protein transport; GO:0060255 regulation of macromolecule metabolic process; GO:1903829 positive regulation of cellular protein localization; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0008366 axon ensheathment; GO:0043065 positive regulation of apoptotic process; GO:0048016 inositol phosphate-mediated signaling; GO:1904589 regulation of protein import; GO:0050896 response to stimulus; GO:0022011 myelination in peripheral nervous system; GO:0070201 regulation of establishment of protein localization; GO:0048468 cell development; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:1905475 regulation of protein localization to membrane; GO:0046902 regulation of mitochondrial membrane permeability; GO:0023056 positive regulation of signaling; GO:0006886 intracellular protein transport; GO:2001235 positive regulation of apoptotic signaling pathway; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:0033157 regulation of intracellular protein transport; GO:0060487 lung epithelial cell differentiation; GO:0042993 positive regulation of transcription factor import into nucleus; GO:0006355 regulation of transcription, DNA-templated; GO:0035556 intracellular signal transduction; GO:0032388 positive regulation of intracellular transport; GO:0051049 regulation of transport; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0033043 regulation of organelle organization; GO:0044802 single-organism membrane organization; GO:0010556 regulation of macromolecule biosynthetic process; GO:0006470 protein dephosphorylation; GO:0051252 regulation of RNA metabolic process; GO:0016311 dephosphorylation; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0010822 positive regulation of mitochondrion organization; GO:0010001 glial cell differentiation; GO:0070727 cellular macromolecule localization; GO:0051170 nuclear import; GO:0044767 single-organism developmental process; GO:0038095 Fc-epsilon receptor signaling pathway; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0051128 regulation of cellular component organization; GO:0009967 positive regulation of signal transduction; GO:0034504 protein localization to nucleus; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:0048762 mesenchymal cell differentiation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0071944 cell periphery; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0008287 protein serine/threonine phosphatase complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:1903293 phosphatase complex; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0005955 calcineurin complex; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0042383 sarcolemma; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0004722 protein serine/threonine phosphatase activity; GO:0016791 phosphatase activity; GO:0043167 ion binding; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0004721 phosphoprotein phosphatase activity; GO:0005516 calmodulin binding; GO:0042578 phosphoric ester hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0019904 protein domain specific binding; GO:0005509 calcium ion binding; GO:0004723 calcium-dependent protein serine/threonine phosphatase activity; ","K06268","PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit","hsa04921 Oxytocin signaling pathway - Homo sapiens (human); hsa05010 Alzheimer's disease - Homo sapiens (human); hsa05152 Tuberculosis - Homo sapiens (human); hsa04650 Natural killer cell mediated cytotoxicity - Homo sapiens (human); hsa04218 Cellular senescence - Homo sapiens (human); hsa04625 C-type lectin receptor signaling pathway - Homo sapiens (human); hsa04370 VEGF signaling pathway - Homo sapiens (human); hsa05031 Amphetamine addiction - Homo sapiens (human); hsa04662 B cell receptor signaling pathway - Homo sapiens (human); hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human); hsa04020 Calcium signaling pathway - Homo sapiens (human); hsa05167 Kaposi's sarcoma-associated herpesvirus infection - Homo sapiens (human); hsa04924 Renin secretion - Homo sapiens (human); hsa04010 MAPK signaling pathway - Homo sapiens (human); hsa05166 HTLV-I infection - Homo sapiens (human); hsa04660 T cell receptor signaling pathway - Homo sapiens (human); hsa04724 Glutamatergic synapse - Homo sapiens (human); hsa04658 Th1 and Th2 cell differentiation - Homo sapiens (human); hsa04114 Oocyte meiosis - Homo sapiens (human); hsa04380 Osteoclast differentiation - Homo sapiens (human); hsa04659 Th17 cell differentiation - Homo sapiens (human); hsa04922 Glucagon signaling pathway - Homo sapiens (human); hsa05014 Amyotrophic lateral sclerosis (ALS) - Homo sapiens (human); hsa04720 Long-term potentiation - Homo sapiens (human); hsa04360 Axon guidance - Homo sapiens (human); hsa04310 Wnt signaling pathway - Homo sapiens (human); ","IPR011992; IPR002048; ","EF-hand domain pair; EF-hand domain; \r"]
["P63162","Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN","SNRPN",24.614,30.121,21.7,6,11,6,0.926,0.905,0.949,1.076,1.081,1.114,1.177,0.000742,"cytoplasm\r","GO:0006396 RNA processing; GO:0006725 cellular aromatic compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0010033 response to organic substance; GO:0050896 response to stimulus; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0008152 metabolic process; GO:0042221 response to chemical; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0090304 nucleic acid metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0044260 cellular macromolecule metabolic process; GO:0009719 response to endogenous stimulus; GO:0010467 gene expression; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0009725 response to hormone; GO:0009987 cellular process; GO:0008380 RNA splicing; GO:0016071 mRNA metabolic process; ","GO:0005685 U1 snRNP; GO:0005686 U2 snRNP; GO:0005737 cytoplasm; GO:0005684 U2-type spliceosomal complex; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0097526 spliceosomal tri-snRNP complex; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0071004 U2-type prespliceosome; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0046540 U4/U6 x U5 tri-snRNP complex; GO:0031981 nuclear lumen; GO:0005681 spliceosomal complex; GO:0097525 spliceosomal snRNP complex; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005687 U4 snRNP; GO:0071013 catalytic step 2 spliceosome; GO:0071010 prespliceosome; GO:1990904 ribonucleoprotein complex; GO:0030532 small nuclear ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0005682 U5 snRNP; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005515 protein binding; GO:0005488 binding; GO:0003676 nucleic acid binding; ","K11100",null,null,"IPR001163; IPR010920; ","\"LSM domain, eukaryotic/archaea-type; LSM domain; \"\r"]
["P63167","Dynein light chain 1, cytoplasmic OS=Homo sapiens OX=9606 GN=DYNLL1","DYNLL1",10.366,17.353,57.3,4,8,2,0.898,0.977,0.984,0.965,1.095,1.078,1.098,0.135,"cytoplasm\r","GO:0098840 protein transport along microtubule; GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0010941 regulation of cell death; GO:0045321 leukocyte activation; GO:0060491 regulation of cell projection assembly; GO:0097659 nucleic acid-templated transcription; GO:0007420 brain development; GO:0060271 cilium assembly; GO:0006914 autophagy; GO:0044237 cellular metabolic process; GO:0010821 regulation of mitochondrion organization; GO:0015031 protein transport; GO:0044782 cilium organization; GO:0048857 neural nucleus development; GO:0021762 substantia nigra development; GO:0008152 metabolic process; GO:1901028 regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; GO:0032879 regulation of localization; GO:1903747 regulation of establishment of protein localization to mitochondrion; GO:0044770 cell cycle phase transition; GO:0043170 macromolecule metabolic process; GO:0090559 regulation of membrane permeability; GO:0008104 protein localization; GO:0044419 interspecies interaction between organisms; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0007399 nervous system development; GO:0000278 mitotic cell cycle; GO:0042325 regulation of phosphorylation; GO:0018130 heterocycle biosynthetic process; GO:0002443 leukocyte mediated immunity; GO:0051174 regulation of phosphorus metabolic process; GO:0030901 midbrain development; GO:0080090 regulation of primary metabolic process; GO:0031346 positive regulation of cell projection organization; GO:0044763 single-organism cellular process; GO:0032774 RNA biosynthetic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0019884 antigen processing and presentation of exogenous antigen; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; GO:0007417 central nervous system development; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II; GO:0000086 G2/M transition of mitotic cell cycle; GO:1901362 organic cyclic compound biosynthetic process; GO:0043068 positive regulation of programmed cell death; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0044707 single-multicellular organism process; GO:0002283 neutrophil activation involved in immune response; GO:0007006 mitochondrial membrane organization; GO:0043067 regulation of programmed cell death; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:1903047 mitotic cell cycle process; GO:1905477 positive regulation of protein localization to membrane; GO:0030705 cytoskeleton-dependent intracellular transport; GO:0060341 regulation of cellular localization; GO:1900740 positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; GO:0046483 heterocycle metabolic process; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0045724 positive regulation of cilium assembly; GO:0051171 regulation of nitrogen compound metabolic process; GO:0044248 cellular catabolic process; GO:1902580 single-organism cellular localization; GO:1901030 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; GO:0007275 multicellular organism development; GO:0032880 regulation of protein localization; GO:0034613 cellular protein localization; GO:0009966 regulation of signal transduction; GO:0044772 mitotic cell cycle phase transition; GO:0044458 motile cilium assembly; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0002376 immune system process; GO:0071702 organic substance transport; GO:0042073 intraciliary transport; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0002263 cell activation involved in immune response; GO:0007017 microtubule-based process; GO:0009892 negative regulation of metabolic process; GO:0030031 cell projection assembly; GO:0045184 establishment of protein localization; GO:0045055 regulated exocytosis; GO:1904951 positive regulation of establishment of protein localization; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0001775 cell activation; GO:0006928 movement of cell or subcellular component; GO:1902857 positive regulation of non-motile cilium assembly; GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; GO:0044839 cell cycle G2/M phase transition; GO:0012501 programmed cell death; GO:0006955 immune response; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:0045936 negative regulation of phosphate metabolic process; GO:1903827 regulation of cellular protein localization; GO:0006887 exocytosis; GO:0023051 regulation of signaling; GO:0006839 mitochondrial transport; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:1902115 regulation of organelle assembly; GO:1903749 positive regulation of establishment of protein localization to mitochondrion; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:2001233 regulation of apoptotic signaling pathway; GO:2001141 regulation of RNA biosynthetic process; GO:0010970 transport along microtubule; GO:0051649 establishment of localization in cell; GO:0010646 regulation of cell communication; GO:0022607 cellular component assembly; GO:0007005 mitochondrion organization; GO:0006915 apoptotic process; GO:1902855 regulation of non-motile cilium assembly; GO:0060322 head development; GO:0033036 macromolecule localization; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0002274 myeloid leukocyte activation; GO:0016236 macroautophagy; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0048002 antigen processing and presentation of peptide antigen; GO:0002446 neutrophil mediated immunity; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0035735 intraciliary transport involved in cilium assembly; GO:0002495 antigen processing and presentation of peptide antigen via MHC class II; GO:0002444 myeloid leukocyte mediated immunity; GO:1902582 single-organism intracellular transport; GO:0010942 positive regulation of cell death; GO:0051050 positive regulation of transport; GO:0016070 RNA metabolic process; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0030030 cell projection organization; GO:0010638 positive regulation of organelle organization; GO:1902117 positive regulation of organelle assembly; GO:0032940 secretion by cell; GO:0019222 regulation of metabolic process; GO:0043299 leukocyte degranulation; GO:0099118 microtubule-based protein transport; GO:0019220 regulation of phosphate metabolic process; GO:0048856 anatomical structure development; GO:0031503 protein complex localization; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0002252 immune effector process; GO:1903829 positive regulation of cellular protein localization; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0048193 Golgi vesicle transport; GO:0043065 positive regulation of apoptotic process; GO:0031344 regulation of cell projection organization; GO:0044087 regulation of cellular component biogenesis; GO:0097711 ciliary basal body docking; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0022406 membrane docking; GO:0099111 microtubule-based transport; GO:0070201 regulation of establishment of protein localization; GO:0071704 organic substance metabolic process; GO:1905475 regulation of protein localization to membrane; GO:0046902 regulation of mitochondrial membrane permeability; GO:0070925 organelle assembly; GO:0023056 positive regulation of signaling; GO:0042326 negative regulation of phosphorylation; GO:0016032 viral process; GO:0006886 intracellular protein transport; GO:2001235 positive regulation of apoptotic signaling pathway; GO:0034641 cellular nitrogen compound metabolic process; GO:0036230 granulocyte activation; GO:0010647 positive regulation of cell communication; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:1902017 regulation of cilium assembly; GO:0006355 regulation of transcription, DNA-templated; GO:0051049 regulation of transport; GO:0035721 intraciliary retrograde transport; GO:0006807 nitrogen compound metabolic process; GO:0044802 single-organism membrane organization; GO:0033043 regulation of organelle organization; GO:0010556 regulation of macromolecule biosynthetic process; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0010822 positive regulation of mitochondrion organization; GO:0002366 leukocyte activation involved in immune response; GO:0019882 antigen processing and presentation; GO:0007018 microtubule-based movement; GO:0042119 neutrophil activation; GO:0070727 cellular macromolecule localization; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0010563 negative regulation of phosphorus metabolic process; GO:0010467 gene expression; GO:0022402 cell cycle process; GO:0051128 regulation of cellular component organization; GO:0009967 positive regulation of signal transduction; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0044089 positive regulation of cellular component biogenesis; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0005623 cell; GO:0099080 supramolecular complex; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0043227 membrane-bounded organelle; GO:0000776 kinetochore; GO:0005929 cilium; GO:0042995 cell projection; GO:0099513 polymeric cytoskeletal fiber; GO:0044430 cytoskeletal part; GO:0012506 vesicle membrane; GO:0005875 microtubule associated complex; GO:0005868 cytoplasmic dynein complex; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0099081 supramolecular polymer; GO:0043231 intracellular membrane-bounded organelle; GO:0030667 secretory granule membrane; GO:0101003 ficolin-1-rich granule membrane; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0005874 microtubule; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0070821 tertiary granule membrane; GO:0044427 chromosomal part; GO:0005856 cytoskeleton; GO:0072686 mitotic spindle; GO:0005815 microtubule organizing center; GO:1902494 catalytic complex; GO:0015630 microtubule cytoskeleton; GO:0044441 ciliary part; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005694 chromosome; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0070820 tertiary granule; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0097542 ciliary tip; GO:0030286 dynein complex; GO:0044463 cell projection part; GO:0005829 cytosol; GO:0005819 spindle; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0098687 chromosomal region; GO:0005634 nucleus; GO:0005813 centrosome; GO:0000775 chromosome, centromeric region; GO:0044444 cytoplasmic part; ","GO:0045505 dynein intermediate chain binding; GO:0003774 motor activity; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0019904 protein domain specific binding; GO:0008022 protein C-terminus binding; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017111 nucleoside-triphosphatase activity; ","K10418","DYNLL; dynein light chain LC8-type","hsa04962 Vasopressin-regulated water reabsorption - Homo sapiens (human); "]
["P63218","Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 OS=Homo sapiens OX=9606 GN=GNG5","GNG5",7.3184,4.6882,27.9,2,3,2,0.912,1.014,0.966,1.036,1.073,1.004,1.076,0.109,"extracellular\r","GO:0044700 single organism signaling; GO:0050794 regulation of cellular process; GO:0042127 regulation of cell proliferation; GO:0071310 cellular response to organic substance; GO:1901700 response to oxygen-containing compound; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:0071377 cellular response to glucagon stimulus; GO:0007165 signal transduction; GO:1901653 cellular response to peptide; GO:0007154 cell communication; GO:2000027 regulation of organ morphogenesis; GO:0071375 cellular response to peptide hormone stimulus; GO:0009719 response to endogenous stimulus; GO:1901652 response to peptide; GO:0009987 cellular process; GO:0070887 cellular response to chemical stimulus; GO:0072513 positive regulation of secondary heart field cardioblast proliferation; GO:0051716 cellular response to stimulus; GO:0003156 regulation of animal organ formation; GO:2000136 regulation of cell proliferation involved in heart morphogenesis; GO:0048522 positive regulation of cellular process; GO:0010033 response to organic substance; GO:2000826 regulation of heart morphogenesis; GO:0023052 signaling; GO:0048518 positive regulation of biological process; GO:0007186 G-protein coupled receptor signaling pathway; GO:0071417 cellular response to organonitrogen compound; GO:2000177 regulation of neural precursor cell proliferation; GO:0003266 regulation of secondary heart field cardioblast proliferation; GO:0010243 response to organonitrogen compound; GO:0042221 response to chemical; GO:1901701 cellular response to oxygen-containing compound; GO:0050789 regulation of biological process; GO:0043434 response to peptide hormone; GO:1901699 cellular response to nitrogen compound; GO:0032870 cellular response to hormone stimulus; GO:0071495 cellular response to endogenous stimulus; GO:0022603 regulation of anatomical structure morphogenesis; GO:2000179 positive regulation of neural precursor cell proliferation; GO:1901698 response to nitrogen compound; GO:0003264 regulation of cardioblast proliferation; GO:0033762 response to glucagon; GO:0009725 response to hormone; GO:0050793 regulation of developmental process; GO:0065007 biological regulation; GO:2000026 regulation of multicellular organismal development; GO:0008284 positive regulation of cell proliferation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0019898 extrinsic component of membrane; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0031234 extrinsic component of cytoplasmic side of plasma membrane; GO:0009898 cytoplasmic side of plasma membrane; GO:0098562 cytoplasmic side of membrane; GO:0070062 extracellular exosome; GO:1902494 catalytic complex; GO:0005834 heterotrimeric G-protein complex; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0098552 side of membrane; GO:0043229 intracellular organelle; GO:1905360 GTPase complex; GO:0098797 plasma membrane protein complex; GO:0019897 extrinsic component of plasma membrane; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0003924 GTPase activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0019904 protein domain specific binding; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017111 nucleoside-triphosphatase activity; GO:0004871 signal transducer activity; GO:0030165 PDZ domain binding; ","K04542","GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5","hsa05200 Pathways in cancer - Homo sapiens (human); hsa04728 Dopaminergic synapse - Homo sapiens (human); hsa04371 Apelin signaling pathway - Homo sapiens (human); hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human); hsa04727 GABAergic synapse - Homo sapiens (human); hsa04014 Ras signaling pathway - Homo sapiens (human); hsa05167 Kaposi's sarcoma-associated herpesvirus infection - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa05034 Alcoholism - Homo sapiens (human); hsa04726 Serotonergic synapse - Homo sapiens (human); hsa04713 Circadian entrainment - Homo sapiens (human); hsa04724 Glutamatergic synapse - Homo sapiens (human); hsa04926 Relaxin signaling pathway - Homo sapiens (human); hsa05032 Morphine addiction - Homo sapiens (human); hsa04725 Cholinergic synapse - Homo sapiens (human); hsa04062 Chemokine signaling pathway - Homo sapiens (human); ","IPR015898; ","G-protein gamma-like domain; \r"]
["P63241","Eukaryotic translation initiation factor 5A-1 OS=Homo sapiens OX=9606 GN=EIF5A","EIF5A",16.832,41.328,55.8,9,19,5,0.942,0.885,0.835,1.079,1.126,1.134,1.254,3.96E-3,"cytoplasm\r","GO:0050658 RNA transport; GO:0006518 peptide metabolic process; GO:0032270 positive regulation of cellular protein metabolic process; GO:0010608 posttranscriptional regulation of gene expression; GO:0043243 positive regulation of protein complex disassembly; GO:0006449 regulation of translational termination; GO:0009891 positive regulation of biosynthetic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0051168 nuclear export; GO:0051169 nuclear transport; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0071427 mRNA-containing ribonucleoprotein complex export from nucleus; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0009893 positive regulation of metabolic process; GO:0050657 nucleic acid transport; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0015931 nucleobase-containing compound transport; GO:0006915 apoptotic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0006412 translation; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0045727 positive regulation of translation; GO:0080090 regulation of primary metabolic process; GO:0045905 positive regulation of translational termination; GO:0043043 peptide biosynthetic process; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0043603 cellular amide metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0006611 protein export from nucleus; GO:0071166 ribonucleoprotein complex localization; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006464 cellular protein modification process; GO:0006913 nucleocytoplasmic transport; GO:0043244 regulation of protein complex disassembly; GO:0036211 protein modification process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0042127 regulation of cell proliferation; GO:0008612 peptidyl-lysine modification to peptidyl-hypusine; GO:0060255 regulation of macromolecule metabolic process; GO:0051028 mRNA transport; GO:0044267 cellular protein metabolic process; GO:0006452 translational frameshifting; GO:1901566 organonitrogen compound biosynthetic process; GO:0051236 establishment of RNA localization; GO:0071704 organic substance metabolic process; GO:0018205 peptidyl-lysine modification; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0006886 intracellular protein transport; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0006406 mRNA export from nucleus; GO:0006448 regulation of translational elongation; GO:0006414 translational elongation; GO:0006403 RNA localization; GO:0006405 RNA export from nucleus; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0034248 regulation of cellular amide metabolic process; GO:0018193 peptidyl-amino acid modification; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0051247 positive regulation of protein metabolic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0071426 ribonucleoprotein complex export from nucleus; GO:0008219 cell death; GO:0051246 regulation of protein metabolic process; GO:0006417 regulation of translation; GO:0031325 positive regulation of cellular metabolic process; GO:0034250 positive regulation of cellular amide metabolic process; GO:0010467 gene expression; GO:0012501 programmed cell death; GO:0043604 amide biosynthetic process; GO:0051128 regulation of cellular component organization; GO:0043412 macromolecule modification; GO:0031328 positive regulation of cellular biosynthetic process; GO:0051179 localization; GO:0071705 nitrogen compound transport; GO:0008284 positive regulation of cell proliferation; GO:0045901 positive regulation of translational elongation; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0005642 annulate lamellae; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0098589 membrane region; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043229 intracellular organelle; GO:0005643 nuclear pore; GO:0005635 nuclear envelope; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044432 endoplasmic reticulum part; GO:0031975 envelope; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0043022 ribosome binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0008135 translation factor activity, RNA binding; GO:0003723 RNA binding; GO:0047485 protein N-terminus binding; GO:0003746 translation elongation factor activity; GO:0017070 U6 snRNA binding; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0017069 snRNA binding; GO:0043021 ribonucleoprotein complex binding; ","K03263",null,null,"IPR008991; IPR012340; IPR014722; IPR020189; ","\"Translation protein SH3-like domain; Nucleic acid-binding, OB-fold; Ribosomal protein L2 domain 2; Translation elongation factor, IF5A C-terminal; \"\r"]
["P67775","Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform OS=Homo sapiens OX=9606 GN=PPP2CA","PPP2CA",35.594,2.9881,45.3,11,18,1,1.031,1.009,1.005,0.984,0.966,1.015,0.974,0.179,"cytoplasm\r","GO:0044700 single organism signaling; GO:0010717 regulation of epithelial to mesenchymal transition; GO:0032270 positive regulation of cellular protein metabolic process; GO:0022414 reproductive process; GO:0006672 ceramide metabolic process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0001558 regulation of cell growth; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0008152 metabolic process; GO:0010719 negative regulation of epithelial to mesenchymal transition; GO:0042516 regulation of tyrosine phosphorylation of Stat3 protein; GO:0044702 single organism reproductive process; GO:0044093 positive regulation of molecular function; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0051347 positive regulation of transferase activity; GO:0031468 nuclear envelope reassembly; GO:0006396 RNA processing; GO:0051716 cellular response to stimulus; GO:0000278 mitotic cell cycle; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0019932 second-messenger-mediated signaling; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0007498 mesoderm development; GO:1903506 regulation of nucleic acid-templated transcription; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:1902532 negative regulation of intracellular signal transduction; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0006402 mRNA catabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0016071 mRNA metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0000003 reproduction; GO:0050794 regulation of cellular process; GO:0043407 negative regulation of MAP kinase activity; GO:0006275 regulation of DNA replication; GO:0042509 regulation of tyrosine phosphorylation of STAT protein; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0071902 positive regulation of protein serine/threonine kinase activity; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0051239 regulation of multicellular organismal process; GO:0044270 cellular nitrogen compound catabolic process; GO:0023057 negative regulation of signaling; GO:0046426 negative regulation of JAK-STAT cascade; GO:0046483 heterocycle metabolic process; GO:0010648 negative regulation of cell communication; GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0051338 regulation of transferase activity; GO:0044248 cellular catabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0001933 negative regulation of protein phosphorylation; GO:0034655 nucleobase-containing compound catabolic process; GO:0008380 RNA splicing; GO:0009966 regulation of signal transduction; GO:1904892 regulation of STAT cascade; GO:1902531 regulation of intracellular signal transduction; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation; GO:0009892 negative regulation of metabolic process; GO:0030155 regulation of cell adhesion; GO:0051247 positive regulation of protein metabolic process; GO:0030111 regulation of Wnt signaling pathway; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0031325 positive regulation of cellular metabolic process; GO:0043409 negative regulation of MAPK cascade; GO:0012501 programmed cell death; GO:0043412 macromolecule modification; GO:0050793 regulation of developmental process; GO:0045936 negative regulation of phosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0051093 negative regulation of developmental process; GO:0010256 endomembrane system organization; GO:0009968 negative regulation of signal transduction; GO:0000188 inactivation of MAPK activity; GO:0006643 membrane lipid metabolic process; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0051241 negative regulation of multicellular organismal process; GO:0006796 phosphate-containing compound metabolic process; GO:0031400 negative regulation of protein modification process; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0071901 negative regulation of protein serine/threonine kinase activity; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0009893 positive regulation of metabolic process; GO:0033673 negative regulation of kinase activity; GO:0006915 apoptotic process; GO:0007084 mitotic nuclear envelope reassembly; GO:1901361 organic cyclic compound catabolic process; GO:0006665 sphingolipid metabolic process; GO:0033674 positive regulation of kinase activity; GO:0045596 negative regulation of cell differentiation; GO:0006629 lipid metabolic process; GO:0032502 developmental process; GO:0045926 negative regulation of growth; GO:0010468 regulation of gene expression; GO:0009888 tissue development; GO:0045937 positive regulation of phosphate metabolic process; GO:0031326 regulation of cellular biosynthetic process; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0051321 meiotic cell cycle; GO:0051348 negative regulation of transferase activity; GO:0043603 cellular amide metabolic process; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0030308 negative regulation of cell growth; GO:0006401 RNA catabolic process; GO:0016070 RNA metabolic process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0051052 regulation of DNA metabolic process; GO:0090304 nucleic acid metabolic process; GO:0019222 regulation of metabolic process; GO:0006469 negative regulation of protein kinase activity; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0043549 regulation of kinase activity; GO:2000026 regulation of multicellular organismal development; GO:0046425 regulation of JAK-STAT cascade; GO:0045859 regulation of protein kinase activity; GO:0016043 cellular component organization; GO:0006997 nucleus organization; GO:0040008 regulation of growth; GO:0006725 cellular aromatic compound metabolic process; GO:0050730 regulation of peptidyl-tyrosine phosphorylation; GO:0043405 regulation of MAP kinase activity; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0006998 nuclear envelope organization; GO:0071704 organic substance metabolic process; GO:1904893 negative regulation of STAT cascade; GO:0043408 regulation of MAPK cascade; GO:0042326 negative regulation of phosphorylation; GO:0034641 cellular nitrogen compound metabolic process; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0035556 intracellular signal transduction; GO:0010629 negative regulation of gene expression; GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein; GO:0001932 regulation of protein phosphorylation; GO:0044802 single-organism membrane organization; GO:0006807 nitrogen compound metabolic process; GO:0031401 positive regulation of protein modification process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0006470 protein dephosphorylation; GO:0001934 positive regulation of protein phosphorylation; GO:0045860 positive regulation of protein kinase activity; GO:0016311 dephosphorylation; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0008219 cell death; GO:0051246 regulation of protein metabolic process; GO:0010563 negative regulation of phosphorus metabolic process; GO:0009057 macromolecule catabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0010467 gene expression; GO:0051128 regulation of cellular component organization; GO:0022402 cell cycle process; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0008287 protein serine/threonine phosphatase complex; GO:0044424 intracellular part; GO:0005623 cell; GO:1903293 phosphatase complex; GO:0044422 organelle part; GO:0000159 protein phosphatase type 2A complex; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:1902494 catalytic complex; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0000922 spindle pole; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005819 spindle; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0098687 chromosomal region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0000775 chromosome, centromeric region; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0050811 GABA receptor binding; GO:0005102 receptor binding; GO:0042578 phosphoric ester hydrolase activity; GO:0003824 catalytic activity; GO:0016791 phosphatase activity; GO:0005488 binding; GO:0043167 ion binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0008022 protein C-terminus binding; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0004721 phosphoprotein phosphatase activity; ","K04382","PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]","hsa05142 Chagas disease (American trypanosomiasis) - Homo sapiens (human); hsa04728 Dopaminergic synapse - Homo sapiens (human); hsa04530 Tight junction - Homo sapiens (human); hsa05160 Hepatitis C - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa04152 AMPK signaling pathway - Homo sapiens (human); hsa04350 TGF-beta signaling pathway - Homo sapiens (human); hsa03015 mRNA surveillance pathway - Homo sapiens (human); hsa04140 Autophagy - animal - Homo sapiens (human); hsa04114 Oocyte meiosis - Homo sapiens (human); hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human); hsa04071 Sphingolipid signaling pathway - Homo sapiens (human); hsa04390 Hippo signaling pathway - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa04730 Long-term depression - Homo sapiens (human); hsa04136 Autophagy - other - Homo sapiens (human); ","IPR029052; IPR004843; IPR006186; ","\"Metallo-dependent phosphatase-like; Calcineurin-like phosphoesterase domain, ApaH type; Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase; \"\r"]
["P67809","Nuclease-sensitive element-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1","YBX1",35.924,93.962,38,7,8,5,0.828,0.906,0.779,1.125,1.092,1.191,1.356,3.8E-3,"nucleus\r","GO:0051093 negative regulation of developmental process; GO:0065008 regulation of biological quality; GO:1903608 protein localization to cytoplasmic stress granule; GO:0097659 nucleic acid-templated transcription; GO:0043009 chordate embryonic development; GO:0010608 posttranscriptional regulation of gene expression; GO:0043489 RNA stabilization; GO:0009891 positive regulation of biosynthetic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0051253 negative regulation of RNA metabolic process; GO:0044237 cellular metabolic process; GO:0051154 negative regulation of striated muscle cell differentiation; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0043170 macromolecule metabolic process; GO:0033365 protein localization to organelle; GO:0009790 embryo development; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0045596 negative regulation of cell differentiation; GO:0051147 regulation of muscle cell differentiation; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0032502 developmental process; GO:0006396 RNA processing; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0000122 negative regulation of transcription from RNA polymerase II promoter; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0051302 regulation of cell division; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0001701 in utero embryonic development; GO:1902679 negative regulation of RNA biosynthetic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0051148 negative regulation of muscle cell differentiation; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0048856 anatomical structure development; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0048255 mRNA stabilization; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0071704 organic substance metabolic process; GO:0043487 regulation of RNA stability; GO:0045892 negative regulation of transcription, DNA-templated; GO:0000398 mRNA splicing, via spliceosome; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0070934 CRD-mediated mRNA stabilization; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0007275 multicellular organism development; GO:0009059 macromolecule biosynthetic process; GO:0034613 cellular protein localization; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0051254 positive regulation of RNA metabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0051781 positive regulation of cell division; GO:0009792 embryo development ending in birth or egg hatching; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0043488 regulation of mRNA stability; GO:0044249 cellular biosynthetic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0051153 regulation of striated muscle cell differentiation; GO:0051641 cellular localization; GO:0009890 negative regulation of biosynthetic process; GO:0070727 cellular macromolecule localization; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0044767 single-organism developmental process; GO:0006366 transcription from RNA polymerase II promoter; GO:0031325 positive regulation of cellular metabolic process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0010467 gene expression; GO:0031327 negative regulation of cellular biosynthetic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0031965 nuclear membrane; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005689 U12-type spliceosomal complex; GO:0043233 organelle lumen; GO:0010494 cytoplasmic stress granule; GO:0043229 intracellular organelle; GO:0070937 CRD-mediated mRNA stability complex; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005635 nuclear envelope; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0071204 histone pre-mRNA 3'end processing complex; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0005681 spliceosomal complex; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0031975 envelope; GO:0035770 ribonucleoprotein granule; GO:1990904 ribonucleoprotein complex; GO:0043234 protein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0003723 RNA binding; GO:0003677 DNA binding; GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding; GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding; GO:0000976 transcription regulatory region sequence-specific DNA binding; GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding; GO:0003690 double-stranded DNA binding; GO:1990837 sequence-specific double-stranded DNA binding; GO:0001012 RNA polymerase II regulatory region DNA binding; GO:0003697 single-stranded DNA binding; GO:0005515 protein binding; GO:0003682 chromatin binding; GO:0043565 sequence-specific DNA binding; GO:0000987 core promoter proximal region sequence-specific DNA binding; GO:0003700 transcription factor activity, sequence-specific DNA binding; GO:0000975 regulatory region DNA binding; GO:0001159 core promoter proximal region DNA binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding; GO:0001067 regulatory region nucleic acid binding; GO:0044212 transcription regulatory region DNA binding; GO:0005488 binding; GO:0001071 nucleic acid binding transcription factor activity; GO:0003676 nucleic acid binding; GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding; GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding; GO:0051020 GTPase binding; GO:0019899 enzyme binding; ","K09276",null,null,"IPR012340; IPR011129; IPR002059; ","\"Nucleic acid-binding, OB-fold; Cold shock domain; Cold-shock protein, DNA-binding; \"\r"]
["P68366","Tubulin alpha-4A chain OS=Homo sapiens OX=9606 GN=TUBA4A","TUBA4A",49.924,161.52,53.8,22,89,4,0.899,0.864,0.944,1.122,1.126,1.098,1.236,0.00136,"cytoskeleton\r","GO:0044085 cellular component biogenesis; GO:0016043 cellular component organization; GO:0060271 cilium assembly; GO:0044699 single-organism process; GO:0002576 platelet degranulation; GO:0097711 ciliary basal body docking; GO:1903047 mitotic cell cycle process; GO:0022406 membrane docking; GO:0044782 cilium organization; GO:0051234 establishment of localization; GO:1902578 single-organism localization; GO:0022607 cellular component assembly; GO:0070925 organelle assembly; GO:0044770 cell cycle phase transition; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0044772 mitotic cell cycle phase transition; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0000278 mitotic cell cycle; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0007017 microtubule-based process; GO:0030031 cell projection assembly; GO:0006810 transport; GO:1902589 single-organism organelle organization; GO:0045055 regulated exocytosis; GO:0030030 cell projection organization; GO:0032940 secretion by cell; GO:0006996 organelle organization; GO:0044839 cell cycle G2/M phase transition; GO:0022402 cell cycle process; GO:0051179 localization; GO:0000086 G2/M transition of mitotic cell cycle; GO:0007049 cell cycle; GO:0006887 exocytosis; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0099513 polymeric cytoskeletal fiber; GO:0005874 microtubule; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0099080 supramolecular complex; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0099081 supramolecular polymer; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0005856 cytoskeleton; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0005200 structural constituent of cytoskeleton; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0003924 GTPase activity; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019001 guanyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005525 GTP binding; GO:0005198 structural molecule activity; GO:0019899 enzyme binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0036094 small molecule binding; ","K07374","TUBA; tubulin alpha","hsa04540 Gap junction - Homo sapiens (human); hsa04210 Apoptosis - Homo sapiens (human); hsa04530 Tight junction - Homo sapiens (human); hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); ","IPR003008; IPR023123; IPR008280; IPR018316; ","\"Tubulin/FtsZ, GTPase domain; Tubulin, C-terminal; Tubulin/FtsZ, C-terminal; Tubulin/FtsZ, 2-layer sandwich domain; \"\r"]
["P68371","Tubulin beta-4B chain OS=Homo sapiens OX=9606 GN=TUBB4B","TUBB4B",49.83,323.31,64.9,20,108,1,1.051,0.923,1.044,0.951,1.051,1.026,1.003,0.94,"cyto_nucl\r","GO:0044085 cellular component biogenesis; GO:0045321 leukocyte activation; GO:0060271 cilium assembly; GO:0044699 single-organism process; GO:0044782 cilium organization; GO:0051234 establishment of localization; GO:0022607 cellular component assembly; GO:0044770 cell cycle phase transition; GO:0001906 cell killing; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0002228 natural killer cell mediated immunity; GO:0000278 mitotic cell cycle; GO:0002443 leukocyte mediated immunity; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0002444 myeloid leukocyte mediated immunity; GO:0006810 transport; GO:1902589 single-organism organelle organization; GO:0001909 leukocyte mediated cytotoxicity; GO:0030030 cell projection organization; GO:0032940 secretion by cell; GO:0006952 defense response; GO:0043299 leukocyte degranulation; GO:0000086 G2/M transition of mitotic cell cycle; GO:0016043 cellular component organization; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0097711 ciliary basal body docking; GO:0050896 response to stimulus; GO:0022406 membrane docking; GO:1903047 mitotic cell cycle process; GO:0045087 innate immune response; GO:0042267 natural killer cell mediated cytotoxicity; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0070925 organelle assembly; GO:0036230 granulocyte activation; GO:0002449 lymphocyte mediated immunity; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0044772 mitotic cell cycle phase transition; GO:0006950 response to stress; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0043312 neutrophil degranulation; GO:0002263 cell activation involved in immune response; GO:0007017 microtubule-based process; GO:0030031 cell projection assembly; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0006996 organelle organization; GO:0001775 cell activation; GO:0006928 movement of cell or subcellular component; GO:0044839 cell cycle G2/M phase transition; GO:0022402 cell cycle process; GO:0006955 immune response; GO:0051179 localization; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0006887 exocytosis; ","GO:0034774 secretory granule lumen; GO:0044421 extracellular region part; GO:0005874 microtubule; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:0099080 supramolecular complex; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0043209 myelin sheath; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0099513 polymeric cytoskeletal fiber; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0099081 supramolecular polymer; GO:0042582 azurophil granule; GO:0031012 extracellular matrix; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0005102 receptor binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0042288 MHC class I protein binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0003924 GTPase activity; GO:0042287 MHC protein binding; GO:0043168 anion binding; GO:0019001 guanyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003723 RNA binding; GO:0003725 double-stranded RNA binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0005200 structural constituent of cytoskeleton; GO:0003676 nucleic acid binding; GO:0032555 purine ribonucleotide binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0051082 unfolded protein binding; GO:0005198 structural molecule activity; GO:0036094 small molecule binding; ","K07375","TUBB; tubulin beta","hsa04540 Gap junction - Homo sapiens (human); hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); ","IPR003008; IPR023123; IPR008280; IPR018316; ","\"Tubulin/FtsZ, GTPase domain; Tubulin, C-terminal; Tubulin/FtsZ, C-terminal; Tubulin/FtsZ, 2-layer sandwich domain; \"\r"]
["P68543","UBX domain-containing protein 2A OS=Homo sapiens OX=9606 GN=UBXN2A","UBXN2A",29.278,1.7892,6.9,2,3,2,1.044,0.973,1.155,0.922,1.027,0.89,0.895,0.169,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0006997 nucleus organization; GO:0016043 cellular component organization; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0010256 endomembrane system organization; GO:0044257 cellular protein catabolic process; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:0060255 regulation of macromolecule metabolic process; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0010498 proteasomal protein catabolic process; GO:0006998 nuclear envelope organization; GO:0071704 organic substance metabolic process; GO:0031396 regulation of protein ubiquitination; GO:0008152 metabolic process; GO:0044248 cellular catabolic process; GO:0006508 proteolysis; GO:0042176 regulation of protein catabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0009987 cellular process; GO:0031468 nuclear envelope reassembly; GO:0043632 modification-dependent macromolecule catabolic process; GO:0010468 regulation of gene expression; GO:0044265 cellular macromolecule catabolic process; GO:0080090 regulation of primary metabolic process; GO:0019941 modification-dependent protein catabolic process; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0044802 single-organism membrane organization; GO:0061025 membrane fusion; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0031323 regulation of cellular metabolic process; GO:0044238 primary metabolic process; GO:1901575 organic substance catabolic process; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0007030 Golgi organization; GO:0051246 regulation of protein metabolic process; GO:0006996 organelle organization; GO:0030163 protein catabolic process; GO:0009057 macromolecule catabolic process; GO:0061024 membrane organization; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0009056 catabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0005783 endoplasmic reticulum; GO:0005801 cis-Golgi network; GO:0005737 cytoplasm; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0033130 acetylcholine receptor binding; GO:0043130 ubiquitin binding; GO:0005515 protein binding; GO:0005102 receptor binding; GO:0032182 ubiquitin-like protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR029071; IPR001012; IPR012989; ","Ubiquitin-related domain; UBX domain; SEP domain; \r"]
["P78316","Nucleolar protein 14 OS=Homo sapiens OX=9606 GN=NOP14","NOP14",97.667,2.3808,1.1,1,1,1,0.844,1.049,0.944,1.028,1.028,1.108,1.115,0.172,"plasma membrane\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); GO:0006725 cellular aromatic compound metabolic process; GO:0034471 ncRNA 5'-end processing; GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); GO:0000460 maturation of 5.8S rRNA; GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0006364 rRNA processing; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0009987 cellular process; GO:0016072 rRNA metabolic process; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); GO:0000966 RNA 5'-end processing; GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); GO:0042274 ribosomal small subunit biogenesis; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0042254 ribosome biogenesis; GO:0044238 primary metabolic process; GO:0016070 RNA metabolic process; GO:0090501 RNA phosphodiester bond hydrolysis; GO:0000469 cleavage involved in rRNA processing; GO:0090304 nucleic acid metabolic process; GO:0000967 rRNA 5'-end processing; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0090305 nucleic acid phosphodiester bond hydrolysis; GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic; GO:0034660 ncRNA metabolic process; GO:0030490 maturation of SSU-rRNA; GO:0071840 cellular component organization or biogenesis; GO:0000478 endonucleolytic cleavage involved in rRNA processing; ","GO:0016020 membrane; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0030688 preribosome, small subunit precursor; GO:0044422 organelle part; GO:0030684 preribosome; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0030692 Noc4p-Nop14p complex; GO:0032040 small-subunit processome; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0030686 90S preribosome; GO:0030689 Noc complex; GO:1990904 ribonucleoprotein complex; GO:0043234 protein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0030515 snoRNA binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0019899 enzyme binding; ","K14766"]
["P78347","General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I","GTF2I",112.42,17.04,7.8,7,8,7,0.884,0.888,0.932,1.063,1.151,1.076,1.217,0.00284,"nucleus\r","GO:0044700 single organism signaling; GO:0051093 negative regulation of developmental process; GO:0065008 regulation of biological quality; GO:0072503 cellular divalent inorganic cation homeostasis; GO:0097659 nucleic acid-templated transcription; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0055065 metal ion homeostasis; GO:0044057 regulation of system process; GO:0043170 macromolecule metabolic process; GO:0014886 transition between slow and fast fiber; GO:2000181 negative regulation of blood vessel morphogenesis; GO:0051716 cellular response to stimulus; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0050801 ion homeostasis; GO:0080090 regulation of primary metabolic process; GO:0055074 calcium ion homeostasis; GO:0098771 inorganic ion homeostasis; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0019725 cellular homeostasis; GO:0032774 RNA biosynthetic process; GO:0090257 regulation of muscle system process; GO:0023052 signaling; GO:0031323 regulation of cellular metabolic process; GO:1901343 negative regulation of vasculature development; GO:0006874 cellular calcium ion homeostasis; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0016525 negative regulation of angiogenesis; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0045765 regulation of angiogenesis; GO:0072507 divalent inorganic cation homeostasis; GO:1901362 organic cyclic compound biosynthetic process; GO:2000026 regulation of multicellular organismal development; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0014733 regulation of skeletal muscle adaptation; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0006352 DNA-templated transcription, initiation; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0051480 regulation of cytosolic calcium ion concentration; GO:0030003 cellular cation homeostasis; GO:0051481 negative regulation of cytosolic calcium ion concentration; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0055082 cellular chemical homeostasis; GO:0051239 regulation of multicellular organismal process; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0055080 cation homeostasis; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006367 transcription initiation from RNA polymerase II promoter; GO:0048878 chemical homeostasis; GO:0006355 regulation of transcription, DNA-templated; GO:1901342 regulation of vasculature development; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0043502 regulation of muscle adaptation; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006873 cellular ion homeostasis; GO:0006366 transcription from RNA polymerase II promoter; GO:0022603 regulation of anatomical structure morphogenesis; GO:0010467 gene expression; GO:0006875 cellular metal ion homeostasis; GO:0050793 regulation of developmental process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042995 cell projection; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0043025 neuronal cell body; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005654 nucleoplasm; GO:0036477 somatodendritic compartment; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0044297 cell body; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding; GO:0003677 DNA binding; GO:0005488 binding; GO:0019901 protein kinase binding; GO:0001071 nucleic acid binding transcription factor activity; GO:0003676 nucleic acid binding; GO:0051019 mitogen-activated protein kinase binding; GO:0005515 protein binding; GO:0019900 kinase binding; GO:0019899 enzyme binding; GO:0003700 transcription factor activity, sequence-specific DNA binding; ","K03121","TFII-I; transcription initiation factor TFII-I","hsa03022 Basal transcription factors - Homo sapiens (human); hsa05168 Herpes simplex infection - Homo sapiens (human); hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human); "]
["P78371","T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2","CCT2",57.488,241.27,41.1,17,32,17,0.944,0.945,0.933,1.064,1.062,1.075,1.134,2.13e-05,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0035036 sperm-egg recognition; GO:0022414 reproductive process; GO:0051973 positive regulation of telomerase activity; GO:0009891 positive regulation of biosynthetic process; GO:1904816 positive regulation of protein localization to chromosome, telomeric region; GO:0032204 regulation of telomere maintenance; GO:1904851 positive regulation of establishment of protein localization to telomere; GO:0006458 'de novo' protein folding; GO:0065003 macromolecular complex assembly; GO:0032879 regulation of localization; GO:0044702 single organism reproductive process; GO:0044093 positive regulation of molecular function; GO:1904874 positive regulation of telomerase RNA localization to Cajal body; GO:0051347 positive regulation of transferase activity; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0002443 leukocyte mediated immunity; GO:0051054 positive regulation of DNA metabolic process; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0019953 sexual reproduction; GO:0031323 regulation of cellular metabolic process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0090666 scaRNA localization to Cajal body; GO:0050790 regulation of catalytic activity; GO:2001252 positive regulation of chromosome organization; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0000003 reproduction; GO:0002283 neutrophil activation involved in immune response; GO:0009988 cell-cell recognition; GO:0032844 regulation of homeostatic process; GO:0060341 regulation of cellular localization; GO:1904356 regulation of telomere maintenance via telomere lengthening; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0009889 regulation of biosynthetic process; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0032880 regulation of protein localization; GO:0006461 protein complex assembly; GO:1904872 regulation of telomerase RNA localization to Cajal body; GO:1904869 regulation of protein localization to Cajal body; GO:0051084 'de novo' posttranslational protein folding; GO:0006403 RNA localization; GO:1904814 regulation of protein localization to chromosome, telomeric region; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0002263 cell activation involved in immune response; GO:2000278 regulation of DNA biosynthetic process; GO:0033044 regulation of chromosome organization; GO:1900182 positive regulation of protein localization to nucleus; GO:0045055 regulated exocytosis; GO:1904951 positive regulation of establishment of protein localization; GO:0031325 positive regulation of cellular metabolic process; GO:0051972 regulation of telomerase activity; GO:0032206 positive regulation of telomere maintenance; GO:0001775 cell activation; GO:0031647 regulation of protein stability; GO:0006955 immune response; GO:0051179 localization; GO:0031328 positive regulation of cellular biosynthetic process; GO:0050821 protein stabilization; GO:0090670 RNA localization to Cajal body; GO:1903827 regulation of cellular protein localization; GO:0006887 exocytosis; GO:0061077 chaperone-mediated protein folding; GO:0044699 single-organism process; GO:1901998 toxin transport; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0006457 protein folding; GO:0009893 positive regulation of metabolic process; GO:0022607 cellular component assembly; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0032846 positive regulation of homeostatic process; GO:0033036 macromolecule localization; GO:0002274 myeloid leukocyte activation; GO:0071822 protein complex subunit organization; GO:0031326 regulation of cellular biosynthetic process; GO:0007339 binding of sperm to zona pellucida; GO:0002446 neutrophil mediated immunity; GO:0048522 positive regulation of cellular process; GO:0032212 positive regulation of telomere maintenance via telomerase; GO:0002444 myeloid leukocyte mediated immunity; GO:0051086 chaperone mediated protein folding independent of cofactor; GO:0009566 fertilization; GO:0050789 regulation of biological process; GO:0051052 regulation of DNA metabolic process; GO:0010638 positive regulation of organelle organization; GO:0032940 secretion by cell; GO:1900180 regulation of protein localization to nucleus; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0070202 regulation of establishment of protein localization to chromosome; GO:0043299 leukocyte degranulation; GO:0070271 protein complex biogenesis; GO:0032210 regulation of telomere maintenance via telomerase; GO:0016043 cellular component organization; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:1903829 positive regulation of cellular protein localization; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0050896 response to stimulus; GO:0008037 cell recognition; GO:0070201 regulation of establishment of protein localization; GO:1904871 positive regulation of protein localization to Cajal body; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0043623 cellular protein complex assembly; GO:0034622 cellular macromolecular complex assembly; GO:1904358 positive regulation of telomere maintenance via telomere lengthening; GO:0033043 regulation of organelle organization; GO:0010556 regulation of macromolecule biosynthetic process; GO:0007338 single fertilization; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0043933 macromolecular complex subunit organization; GO:0043085 positive regulation of catalytic activity; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0070203 regulation of establishment of protein localization to telomere; GO:0044703 multi-organism reproductive process; GO:0051131 chaperone-mediated protein complex assembly; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0051128 regulation of cellular component organization; GO:2000573 positive regulation of DNA biosynthetic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0044421 extracellular region part; GO:0005874 microtubule; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:0099080 supramolecular complex; GO:0044422 organelle part; GO:0002199 zona pellucida receptor complex; GO:0005775 vacuolar lumen; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0043209 myelin sheath; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0044445 cytosolic part; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0005832 chaperonin-containing T-complex; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0099081 supramolecular polymer; GO:0042582 azurophil granule; GO:0031012 extracellular matrix; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0101031 chaperone complex; GO:0044297 cell body; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0031625 ubiquitin protein ligase binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0044183 protein binding involved in protein folding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0051082 unfolded protein binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0019899 enzyme binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K09494",null,null,"IPR027410; IPR027409; IPR027413; ","TCP-1-like chaperonin intermediate domain; GroEL-like apical domain; GroEL-like equatorial domain; \r"]
["P78527","DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC","PRKDC",469.08,323.31,21.9,84,114,84,0.909,0.92,0.939,1.054,1.087,1.098,1.17,0.000539,"cytoplasm\r","GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:1902807 negative regulation of cell cycle G1/S phase transition; GO:0048732 gland development; GO:0090342 regulation of cell aging; GO:0022414 reproductive process; GO:0035282 segmentation; GO:0043009 chordate embryonic development; GO:0002698 negative regulation of immune effector process; GO:0009891 positive regulation of biosynthetic process; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0045927 positive regulation of growth; GO:0042110 T cell activation; GO:0048145 regulation of fibroblast proliferation; GO:0072431 signal transduction involved in mitotic G1 DNA damage checkpoint; GO:1902403 signal transduction involved in mitotic DNA integrity checkpoint; GO:0008152 metabolic process; GO:2001229 negative regulation of response to gamma radiation; GO:0048146 positive regulation of fibroblast proliferation; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0009790 embryo development; GO:2000772 regulation of cellular senescence; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0000278 mitotic cell cycle; GO:0044773 mitotic DNA damage checkpoint; GO:0080090 regulation of primary metabolic process; GO:2000134 negative regulation of G1/S transition of mitotic cell cycle; GO:0044763 single-organism cellular process; GO:0002520 immune system development; GO:0010243 response to organonitrogen compound; GO:0014823 response to activity; GO:0080135 regulation of cellular response to stress; GO:1902400 intracellular signal transduction involved in G1 DNA damage checkpoint; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0060548 negative regulation of cell death; GO:2001228 regulation of response to gamma radiation; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0000003 reproduction; GO:0072359 circulatory system development; GO:0016310 phosphorylation; GO:0044707 single-multicellular organism process; GO:0097190 apoptotic signaling pathway; GO:0016445 somatic diversification of immunoglobulins; GO:0001819 positive regulation of cytokine production; GO:0006259 DNA metabolic process; GO:0007389 pattern specification process; GO:1901700 response to oxygen-containing compound; GO:0002328 pro-B cell differentiation; GO:0048519 negative regulation of biological process; GO:0001756 somitogenesis; GO:1903047 mitotic cell cycle process; GO:0030098 lymphocyte differentiation; GO:0009653 anatomical structure morphogenesis; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:1902402 signal transduction involved in mitotic DNA damage checkpoint; GO:0044819 mitotic G1/S transition checkpoint; GO:1902680 positive regulation of RNA biosynthetic process; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0030217 T cell differentiation; GO:0002681 somatic recombination of T cell receptor gene segments; GO:0016567 protein ubiquitination; GO:0006950 response to stress; GO:0008283 cell proliferation; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0006974 cellular response to DNA damage stimulus; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage; GO:0002638 negative regulation of immunoglobulin production; GO:0032446 protein modification by small protein conjugation; GO:0002568 somatic diversification of T cell receptor genes; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0031647 regulation of protein stability; GO:0043412 macromolecule modification; GO:0045936 negative regulation of phosphate metabolic process; GO:0008284 positive regulation of cell proliferation; GO:2000045 regulation of G1/S transition of mitotic cell cycle; GO:0051093 negative regulation of developmental process; GO:0018209 peptidyl-serine modification; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0031400 negative regulation of protein modification process; GO:0006796 phosphate-containing compound metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0045930 negative regulation of mitotic cell cycle; GO:0007165 signal transduction; GO:0000077 DNA damage checkpoint; GO:1901653 cellular response to peptide; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0006915 apoptotic process; GO:1902806 regulation of cell cycle G1/S phase transition; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0051726 regulation of cell cycle; GO:0006310 DNA recombination; GO:0031571 mitotic G1 DNA damage checkpoint; GO:0031326 regulation of cellular biosynthetic process; GO:0033077 T cell differentiation in thymus; GO:0002700 regulation of production of molecular mediator of immune response; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0010942 positive regulation of cell death; GO:0071417 cellular response to organonitrogen compound; GO:0032868 response to insulin; GO:0036211 protein modification process; GO:0072401 signal transduction involved in DNA integrity checkpoint; GO:0016043 cellular component organization; GO:0072395 signal transduction involved in cell cycle checkpoint; GO:0045786 negative regulation of cell cycle; GO:0043069 negative regulation of programmed cell death; GO:0040008 regulation of growth; GO:0032479 regulation of type I interferon production; GO:1901988 negative regulation of cell cycle phase transition; GO:0060255 regulation of macromolecule metabolic process; GO:0010332 response to gamma radiation; GO:0071310 cellular response to organic substance; GO:0006302 double-strand break repair; GO:0043065 positive regulation of apoptotic process; GO:0048638 regulation of developmental growth; GO:0097193 intrinsic apoptotic signaling pathway; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:0006468 protein phosphorylation; GO:0043066 negative regulation of apoptotic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0033153 T cell receptor V(D)J recombination; GO:0009952 anterior/posterior pattern specification; GO:0006355 regulation of transcription, DNA-templated; GO:0072422 signal transduction involved in DNA damage checkpoint; GO:0035556 intracellular signal transduction; GO:0000726 non-recombinational repair; GO:0009792 embryo development ending in birth or egg hatching; GO:0001932 regulation of protein phosphorylation; GO:0031648 protein destabilization; GO:0030097 hemopoiesis; GO:0018193 peptidyl-amino acid modification; GO:0006281 DNA repair; GO:1901701 cellular response to oxygen-containing compound; GO:0002377 immunoglobulin production; GO:0008219 cell death; GO:0071495 cellular response to endogenous stimulus; GO:0002684 positive regulation of immune system process; GO:0010563 negative regulation of phosphorus metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0001817 regulation of cytokine production; GO:0022402 cell cycle process; GO:0042981 regulation of apoptotic process; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0032481 positive regulation of type I interferon production; GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0007420 brain development; GO:0016233 telomere capping; GO:0002320 lymphoid progenitor cell differentiation; GO:0007507 heart development; GO:0051240 positive regulation of multicellular organismal process; GO:0044702 single organism reproductive process; GO:0009719 response to endogenous stimulus; GO:0018105 peptidyl-serine phosphorylation; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:1901652 response to peptide; GO:0007399 nervous system development; GO:0002244 hematopoietic progenitor cell differentiation; GO:0003006 developmental process involved in reproduction; GO:0051174 regulation of phosphorus metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0048536 spleen development; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0030183 B cell differentiation; GO:0002701 negative regulation of production of molecular mediator of immune response; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0072413 signal transduction involved in mitotic cell cycle checkpoint; GO:0010948 negative regulation of cell cycle process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0007417 central nervous system development; GO:0090344 negative regulation of cell aging; GO:0032869 cellular response to insulin stimulus; GO:0010604 positive regulation of macromolecule metabolic process; GO:0002682 regulation of immune system process; GO:0006464 cellular protein modification process; GO:0032200 telomere organization; GO:0051094 positive regulation of developmental process; GO:0043068 positive regulation of programmed cell death; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0007346 regulation of mitotic cell cycle; GO:0042127 regulation of cell proliferation; GO:0009628 response to abiotic stimulus; GO:0002200 somatic diversification of immune receptors; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0043067 regulation of programmed cell death; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0002562 somatic diversification of immune receptors via germline recombination within a single locus; GO:0060249 anatomical structure homeostasis; GO:0051239 regulation of multicellular organismal process; GO:0002326 B cell lineage commitment; GO:1901987 regulation of cell cycle phase transition; GO:0010628 positive regulation of gene expression; GO:0033152 immunoglobulin V(D)J recombination; GO:0007093 mitotic cell cycle checkpoint; GO:0051171 regulation of nitrogen compound metabolic process; GO:0001933 negative regulation of protein phosphorylation; GO:0007275 multicellular organism development; GO:0051254 positive regulation of RNA metabolic process; GO:0048731 system development; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0045165 cell fate commitment; GO:0048538 thymus development; GO:0051276 chromosome organization; GO:0006793 phosphorus metabolic process; GO:0001775 cell activation; GO:0012501 programmed cell death; GO:0031328 positive regulation of cellular biosynthetic process; GO:0050793 regulation of developmental process; GO:0002360 T cell lineage commitment; GO:0000723 telomere maintenance; GO:0061053 somite development; GO:0044783 G1 DNA damage checkpoint; GO:0007154 cell communication; GO:0044774 mitotic DNA integrity checkpoint; GO:1901991 negative regulation of mitotic cell cycle phase transition; GO:0042752 regulation of circadian rhythm; GO:0000075 cell cycle checkpoint; GO:0060322 head development; GO:0009314 response to radiation; GO:0002697 regulation of immune effector process; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0060429 epithelium development; GO:0048639 positive regulation of developmental growth; GO:0009888 tissue development; GO:0002521 leukocyte differentiation; GO:0031570 DNA integrity checkpoint; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0010623 programmed cell death involved in cell development; GO:0035234 ectopic germ cell programmed cell death; GO:0097681 double-strand break repair via alternative nonhomologous end joining; GO:0002683 negative regulation of immune system process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0090304 nucleic acid metabolic process; GO:0043434 response to peptide hormone; GO:0002440 production of molecular mediator of immune response; GO:1901699 cellular response to nitrogen compound; GO:0032870 cellular response to hormone stimulus; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0048856 anatomical structure development; GO:0006303 double-strand break repair via nonhomologous end joining; GO:0006725 cellular aromatic compound metabolic process; GO:0048660 regulation of smooth muscle cell proliferation; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0042326 negative regulation of phosphorylation; GO:0071375 cellular response to peptide hormone stimulus; GO:0042770 signal transduction in response to DNA damage; GO:0009987 cellular process; GO:0042113 B cell activation; GO:2000773 negative regulation of cellular senescence; GO:0003002 regionalization; GO:0016444 somatic cell DNA recombination; GO:0016447 somatic recombination of immunoglobulin gene segments; GO:0006807 nitrogen compound metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0046649 lymphocyte activation; GO:0033151 V(D)J recombination; GO:0048585 negative regulation of response to stimulus; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0048534 hematopoietic or lymphoid organ development; GO:0010212 response to ionizing radiation; GO:0048511 rhythmic process; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0002637 regulation of immunoglobulin production; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0009725 response to hormone; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0070419 nonhomologous end joining complex; GO:0000784 nuclear chromosome, telomeric region; GO:0000781 chromosome, telomeric region; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044454 nuclear chromosome part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:1990391 DNA repair complex; GO:0005730 nucleolus; GO:0005667 transcription factor complex; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0098687 chromosomal region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031012 extracellular matrix; GO:0005634 nucleus; GO:0000228 nuclear chromosome; GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0004677 DNA-dependent protein kinase activity; GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0003690 double-stranded DNA binding; GO:0005515 protein binding; GO:0004672 protein kinase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016301 kinase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003723 RNA binding; GO:0003677 DNA binding; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003676 nucleic acid binding; GO:0032555 purine ribonucleotide binding; GO:0004674 protein serine/threonine kinase activity; GO:0001883 purine nucleoside binding; GO:0019899 enzyme binding; GO:0008134 transcription factor binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0036094 small molecule binding; ","K06642","PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]","hsa03450 Non-homologous end-joining - Homo sapiens (human); hsa04110 Cell cycle - Homo sapiens (human); ","IPR000403; IPR011989; IPR011009; IPR012582; IPR003151; IPR014009; IPR016024; IPR003152; ","\"Phosphatidylinositol 3-/4-kinase, catalytic domain; Armadillo-like helical; Protein kinase-like domain; NUC194; PIK-related kinase, FAT; PIK-related kinase; Armadillo-type fold; FATC domain; \"\r"]
["P80108","Phosphatidylinositol-glycan-specific phospholipase D OS=Homo sapiens OX=9606 GN=GPLD1","GPLD1",92.335,5.2767,2.4,2,2,2,0.972,1.009,0.985,1.077,0.975,0.991,1.026,0.491,"extracellular\r","GO:0044700 single organism signaling; GO:0090130 tissue migration; GO:0010941 regulation of cell death; GO:0050796 regulation of insulin secretion; GO:0009891 positive regulation of biosynthetic process; GO:0044255 cellular lipid metabolic process; GO:0002793 positive regulation of peptide secretion; GO:0044237 cellular metabolic process; GO:0010594 regulation of endothelial cell migration; GO:0001525 angiogenesis; GO:0008152 metabolic process; GO:0044093 positive regulation of molecular function; GO:0046889 positive regulation of lipid biosynthetic process; GO:0051716 cellular response to stimulus; GO:0071214 cellular response to abiotic stimulus; GO:0080090 regulation of primary metabolic process; GO:0036315 cellular response to sterol; GO:0044763 single-organism cellular process; GO:0048870 cell motility; GO:0097306 cellular response to alcohol; GO:0071396 cellular response to lipid; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0010243 response to organonitrogen compound; GO:0048583 regulation of response to stimulus; GO:0046890 regulation of lipid biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:1901698 response to nitrogen compound; GO:0051223 regulation of protein transport; GO:0072359 circulatory system development; GO:0044707 single-multicellular organism process; GO:0010896 regulation of triglyceride catabolic process; GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0010897 negative regulation of triglyceride catabolic process; GO:0010983 positive regulation of high-density lipoprotein particle clearance; GO:1901700 response to oxygen-containing compound; GO:0048519 negative regulation of biological process; GO:0010906 regulation of glucose metabolic process; GO:0090277 positive regulation of peptide hormone secretion; GO:0009653 anatomical structure morphogenesis; GO:0042493 response to drug; GO:0051345 positive regulation of hydrolase activity; GO:0051043 regulation of membrane protein ectodomain proteolysis; GO:2000145 regulation of cell motility; GO:0009889 regulation of biosynthetic process; GO:0009896 positive regulation of catabolic process; GO:0042176 regulation of protein catabolic process; GO:0050778 positive regulation of immune response; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0051270 regulation of cellular component movement; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:1901576 organic substance biosynthetic process; GO:0031325 positive regulation of cellular metabolic process; GO:0034014 response to triglyceride; GO:0019637 organophosphate metabolic process; GO:0006644 phospholipid metabolic process; GO:0043412 macromolecule modification; GO:0006507 GPI anchor release; GO:0046470 phosphatidylcholine metabolic process; GO:0008286 insulin receptor signaling pathway; GO:0009746 response to hexose; GO:0046486 glycerolipid metabolic process; GO:0051674 localization of cell; GO:0001568 blood vessel development; GO:0051216 cartilage development; GO:0040017 positive regulation of locomotion; GO:0048869 cellular developmental process; GO:0031331 positive regulation of cellular catabolic process; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0051046 regulation of secretion; GO:0009058 biosynthetic process; GO:0006796 phosphate-containing compound metabolic process; GO:0007165 signal transduction; GO:1901653 cellular response to peptide; GO:0009893 positive regulation of metabolic process; GO:0032846 positive regulation of homeostatic process; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0006629 lipid metabolic process; GO:0045833 negative regulation of lipid metabolic process; GO:0045937 positive regulation of phosphate metabolic process; GO:0031326 regulation of cellular biosynthetic process; GO:0001944 vasculature development; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:1903530 regulation of secretion by cell; GO:0010038 response to metal ion; GO:0010942 positive regulation of cell death; GO:0010907 positive regulation of glucose metabolic process; GO:0071417 cellular response to organonitrogen compound; GO:0032868 response to insulin; GO:0001667 ameboidal-type cell migration; GO:0065009 regulation of molecular function; GO:0036211 protein modification process; GO:0051222 positive regulation of protein transport; GO:0016477 cell migration; GO:0010867 positive regulation of triglyceride biosynthetic process; GO:1903509 liposaccharide metabolic process; GO:0043534 blood vessel endothelial cell migration; GO:0010595 positive regulation of endothelial cell migration; GO:0071467 cellular response to pH; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0043065 positive regulation of apoptotic process; GO:1900076 regulation of cellular response to insulin stimulus; GO:0071704 organic substance metabolic process; GO:0033993 response to lipid; GO:0030154 cell differentiation; GO:0009268 response to pH; GO:0045862 positive regulation of proteolysis; GO:0023056 positive regulation of signaling; GO:0071397 cellular response to cholesterol; GO:0002757 immune response-activating signal transduction; GO:0051592 response to calcium ion; GO:0010984 regulation of lipoprotein particle clearance; GO:0009895 negative regulation of catabolic process; GO:0010647 positive regulation of cell communication; GO:0009059 macromolecule biosynthetic process; GO:0032024 positive regulation of insulin secretion; GO:0010921 regulation of phosphatase activity; GO:0097241 hematopoietic stem cell migration to bone marrow; GO:0051049 regulation of transport; GO:0002042 cell migration involved in sprouting angiogenesis; GO:0050995 negative regulation of lipid catabolic process; GO:0010634 positive regulation of epithelial cell migration; GO:0044249 cellular biosynthetic process; GO:0043085 positive regulation of catalytic activity; GO:1901701 cellular response to oxygen-containing compound; GO:0034645 cellular macromolecule biosynthetic process; GO:0071495 cellular response to endogenous stimulus; GO:0002684 positive regulation of immune system process; GO:0002430 complement receptor mediated signaling pathway; GO:0042981 regulation of apoptotic process; GO:0065008 regulation of biological quality; GO:0030335 positive regulation of cell migration; GO:0032270 positive regulation of cellular protein metabolic process; GO:0007166 cell surface receptor signaling pathway; GO:0019216 regulation of lipid metabolic process; GO:0009749 response to glucose; GO:0042157 lipoprotein metabolic process; GO:0008285 negative regulation of cell proliferation; GO:0043542 endothelial cell migration; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0009719 response to endogenous stimulus; GO:0010562 positive regulation of phosphorus metabolic process; GO:0009743 response to carbohydrate; GO:0061448 connective tissue development; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:1901652 response to peptide; GO:0044765 single-organism transport; GO:0014070 response to organic cyclic compound; GO:0051174 regulation of phosphorus metabolic process; GO:0010632 regulation of epithelial cell migration; GO:0031329 regulation of cellular catabolic process; GO:0001503 ossification; GO:0009894 regulation of catabolic process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0051272 positive regulation of cellular component movement; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0048513 animal organ development; GO:0046883 regulation of hormone secretion; GO:0051336 regulation of hydrolase activity; GO:0010631 epithelial cell migration; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0034284 response to monosaccharide; GO:0032869 cellular response to insulin stimulus; GO:0050714 positive regulation of protein secretion; GO:0090208 positive regulation of triglyceride metabolic process; GO:0010817 regulation of hormone levels; GO:0010604 positive regulation of macromolecule metabolic process; GO:0002682 regulation of immune system process; GO:0006464 cellular protein modification process; GO:0006497 protein lipidation; GO:0050994 regulation of lipid catabolic process; GO:0043068 positive regulation of programmed cell death; GO:0051047 positive regulation of secretion; GO:0050794 regulation of cellular process; GO:0043687 post-translational protein modification; GO:0042127 regulation of cell proliferation; GO:0009628 response to abiotic stimulus; GO:0043067 regulation of programmed cell death; GO:0044267 cellular protein metabolic process; GO:0097164 ammonium ion metabolic process; GO:0010982 regulation of high-density lipoprotein particle clearance; GO:0048523 negative regulation of cellular process; GO:2000147 positive regulation of cell motility; GO:0090132 epithelium migration; GO:0032844 regulation of homeostatic process; GO:0051239 regulation of multicellular organismal process; GO:0060341 regulation of cellular localization; GO:0010922 positive regulation of phosphatase activity; GO:0010692 regulation of alkaline phosphatase activity; GO:1902578 single-organism localization; GO:0042268 regulation of cytolysis; GO:0006505 GPI anchor metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0090207 regulation of triglyceride metabolic process; GO:0032880 regulation of protein localization; GO:0007275 multicellular organism development; GO:0071401 cellular response to triglyceride; GO:0002253 activation of immune response; GO:0090087 regulation of peptide transport; GO:0048731 system development; GO:0030334 regulation of cell migration; GO:0097305 response to alcohol; GO:0071407 cellular response to organic cyclic compound; GO:0072358 cardiovascular system development; GO:0030162 regulation of proteolysis; GO:0010676 positive regulation of cellular carbohydrate metabolic process; GO:0006109 regulation of carbohydrate metabolic process; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0031330 negative regulation of cellular catabolic process; GO:0051247 positive regulation of protein metabolic process; GO:1904951 positive regulation of establishment of protein localization; GO:0006793 phosphorus metabolic process; GO:0046887 positive regulation of hormone secretion; GO:0006928 movement of cell or subcellular component; GO:0010694 positive regulation of alkaline phosphatase activity; GO:0031328 positive regulation of cellular biosynthetic process; GO:0010866 regulation of triglyceride biosynthetic process; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0071248 cellular response to metal ion; GO:1901564 organonitrogen compound metabolic process; GO:0045913 positive regulation of carbohydrate metabolic process; GO:0006643 membrane lipid metabolic process; GO:0051234 establishment of localization; GO:0045919 positive regulation of cytolysis; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0070633 transepithelial transport; GO:0035303 regulation of dephosphorylation; GO:0006650 glycerophospholipid metabolic process; GO:0002062 chondrocyte differentiation; GO:0046488 phosphatidylinositol metabolic process; GO:0010035 response to inorganic substance; GO:0048514 blood vessel morphogenesis; GO:0042158 lipoprotein biosynthetic process; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0070887 cellular response to chemical stimulus; GO:0002040 sprouting angiogenesis; GO:0032502 developmental process; GO:0009888 tissue development; GO:0010675 regulation of cellular carbohydrate metabolic process; GO:0006664 glycolipid metabolic process; GO:0048522 positive regulation of cellular process; GO:0051050 positive regulation of transport; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0035306 positive regulation of dephosphorylation; GO:0043434 response to peptide hormone; GO:1903532 positive regulation of secretion by cell; GO:1901699 cellular response to nitrogen compound; GO:0032870 cellular response to hormone stimulus; GO:0019222 regulation of metabolic process; GO:0071241 cellular response to inorganic substance; GO:0019220 regulation of phosphate metabolic process; GO:0036314 response to sterol; GO:0040011 locomotion; GO:0048856 anatomical structure development; GO:0001501 skeletal system development; GO:0035690 cellular response to drug; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0070201 regulation of establishment of protein localization; GO:0002791 regulation of peptide secretion; GO:0051044 positive regulation of membrane protein ectodomain proteolysis; GO:0071375 cellular response to peptide hormone stimulus; GO:0050708 regulation of protein secretion; GO:0009987 cellular process; GO:0006501 C-terminal protein lipidation; GO:0010986 positive regulation of lipoprotein particle clearance; GO:0035701 hematopoietic stem cell migration; GO:0006807 nitrogen compound metabolic process; GO:0071277 cellular response to calcium ion; GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus; GO:0018410 C-terminal protein amino acid modification; GO:0048518 positive regulation of biological process; GO:0045834 positive regulation of lipid metabolic process; GO:0070723 response to cholesterol; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0090276 regulation of peptide hormone secretion; GO:0090209 negative regulation of triglyceride metabolic process; GO:0045732 positive regulation of protein catabolic process; GO:0009725 response to hormone; GO:0040012 regulation of locomotion; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005765 lysosomal membrane; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0005576 extracellular region; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031012 extracellular matrix; GO:0044437 vacuolar part; GO:0005578 proteinaceous extracellular matrix; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0042578 phosphoric ester hydrolase activity; GO:0016247 channel regulator activity; GO:0003824 catalytic activity; GO:0016788 hydrolase activity, acting on ester bonds; GO:0004630 phospholipase D activity; GO:0004620 phospholipase activity; GO:0008081 phosphoric diester hydrolase activity; GO:0016787 hydrolase activity; GO:0004621 glycosylphosphatidylinositol phospholipase D activity; GO:0017080 sodium channel regulator activity; GO:0016298 lipase activity; GO:0098772 molecular function regulator; ","K01127","E3.1.4.50; glycosylphosphatidylinositol phospholipase D [EC:3.1.4.50]","hsa00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis - Homo sapiens (human); ","IPR029002; ","Phospholipase C/D; \r"]
["P80217","Interferon-induced 35 kDa protein OS=Homo sapiens OX=9606 GN=IFI35","IFI35",31.546,6.5313,8.4,2,2,2,0.879,0.934,0.876,1.11,1.152,1.046,1.23,0.0041,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0060337 type I interferon signaling pathway; GO:0051716 cellular response to stimulus; GO:0034097 response to cytokine; GO:0006950 response to stress; GO:0007166 cell surface receptor signaling pathway; GO:0071310 cellular response to organic substance; GO:0044699 single-organism process; GO:0034340 response to type I interferon; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0023052 signaling; GO:0050896 response to stimulus; GO:0071345 cellular response to cytokine stimulus; GO:0045087 innate immune response; GO:0007165 signal transduction; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0007154 cell communication; GO:0071357 cellular response to type I interferon; GO:0006952 defense response; GO:0006955 immune response; GO:0009987 cellular process; GO:0019221 cytokine-mediated signaling pathway; GO:0070887 cellular response to chemical stimulus; GO:0065007 biological regulation; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR009938; IPR009909; ","\"Nmi/IFP 35 domain, N-terminal; Nmi/IFP 35 domain; \"\r"]
["P80303","Nucleobindin-2 OS=Homo sapiens OX=9606 GN=NUCB2","NUCB2",50.222,109.94,30.5,10,18,10,1.097,1.108,1.103,0.886,0.913,0.93,0.825,0.000181,"extracellular\r",null,"GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005635 nuclear envelope; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0031975 envelope; GO:0005793 endoplasmic reticulum-Golgi intermediate compartment; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003677 DNA binding; GO:0005488 binding; GO:0043167 ion binding; GO:0003676 nucleic acid binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0005509 calcium ion binding; ","K20371",null,null,"IPR002048; IPR011992; ","EF-hand domain; EF-hand domain pair; \r"]
["P80511","Protein S100-A12 OS=Homo sapiens OX=9606 GN=S100A12","S100A12",10.575,6.774,26.1,3,7,3,0.494,0.466,0.502,1.563,1.502,1.558,3.162,7.73e-07,"cytoplasm\r","GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0045321 leukocyte activation; GO:0098542 defense response to other organism; GO:0031347 regulation of defense response; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0009607 response to biotic stimulus; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling; GO:0044093 positive regulation of molecular function; GO:0009306 protein secretion; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0051347 positive regulation of transferase activity; GO:0008104 protein localization; GO:0001906 cell killing; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0051174 regulation of phosphorus metabolic process; GO:0009620 response to fungus; GO:0002443 leukocyte mediated immunity; GO:0080090 regulation of primary metabolic process; GO:0050729 positive regulation of inflammatory response; GO:0044763 single-organism cellular process; GO:0048870 cell motility; GO:0031323 regulation of cellular metabolic process; GO:0006935 chemotaxis; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0006810 transport; GO:1903506 regulation of nucleic acid-templated transcription; GO:0051092 positive regulation of NF-kappaB transcription factor activity; GO:0050900 leukocyte migration; GO:0050790 regulation of catalytic activity; GO:0051090 regulation of sequence-specific DNA binding transcription factor activity; GO:0048583 regulation of response to stimulus; GO:0010604 positive regulation of macromolecule metabolic process; GO:0042330 taxis; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0002283 neutrophil activation involved in immune response; GO:0031399 regulation of protein modification process; GO:0071902 positive regulation of protein serine/threonine kinase activity; GO:0060326 cell chemotaxis; GO:0080134 regulation of response to stress; GO:0097530 granulocyte migration; GO:0031349 positive regulation of defense response; GO:0009410 response to xenobiotic stimulus; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0031640 killing of cells of other organism; GO:0009889 regulation of biosynthetic process; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0009966 regulation of signal transduction; GO:0009617 response to bacterium; GO:0050663 cytokine secretion; GO:1902531 regulation of intracellular signal transduction; GO:0006950 response to stress; GO:0016192 vesicle-mediated transport; GO:0032101 regulation of response to external stimulus; GO:0071702 organic substance transport; GO:0002376 immune system process; GO:0002548 monocyte chemotaxis; GO:0002263 cell activation involved in immune response; GO:0045184 establishment of protein localization; GO:0071674 mononuclear cell migration; GO:0045055 regulated exocytosis; GO:0043406 positive regulation of MAP kinase activity; GO:0051247 positive regulation of protein metabolic process; GO:0001816 cytokine production; GO:0031325 positive regulation of cellular metabolic process; GO:0044364 disruption of cells of other organism; GO:0006928 movement of cell or subcellular component; GO:0001775 cell activation; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0006955 immune response; GO:0006887 exocytosis; GO:0051674 localization of cell; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0035821 modification of morphology or physiology of other organism; GO:0045576 mast cell activation; GO:0051234 establishment of localization; GO:1990266 neutrophil migration; GO:2001141 regulation of RNA biosynthetic process; GO:0010646 regulation of cell communication; GO:0071621 granulocyte chemotaxis; GO:0097529 myeloid leukocyte migration; GO:0009893 positive regulation of metabolic process; GO:0032103 positive regulation of response to external stimulus; GO:0033036 macromolecule localization; GO:0033674 positive regulation of kinase activity; GO:0070887 cellular response to chemical stimulus; GO:0002274 myeloid leukocyte activation; GO:0010468 regulation of gene expression; GO:0045937 positive regulation of phosphate metabolic process; GO:0031326 regulation of cellular biosynthetic process; GO:0002446 neutrophil mediated immunity; GO:0048522 positive regulation of cellular process; GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity; GO:0002444 myeloid leukocyte mediated immunity; GO:0030593 neutrophil chemotaxis; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0032940 secretion by cell; GO:0006954 inflammatory response; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0006952 defense response; GO:0043299 leukocyte degranulation; GO:0040011 locomotion; GO:0043549 regulation of kinase activity; GO:0071466 cellular response to xenobiotic stimulus; GO:0045859 regulation of protein kinase activity; GO:0016477 cell migration; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0043405 regulation of MAP kinase activity; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0045087 innate immune response; GO:0006805 xenobiotic metabolic process; GO:0043408 regulation of MAPK cascade; GO:0023056 positive regulation of signaling; GO:0036230 granulocyte activation; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:0006355 regulation of transcription, DNA-templated; GO:0042742 defense response to bacterium; GO:0001932 regulation of protein phosphorylation; GO:0031401 positive regulation of protein modification process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0001934 positive regulation of protein phosphorylation; GO:0045860 positive regulation of protein kinase activity; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0043085 positive regulation of catalytic activity; GO:0002366 leukocyte activation involved in immune response; GO:0050832 defense response to fungus; GO:0042119 neutrophil activation; GO:0030595 leukocyte chemotaxis; GO:0051246 regulation of protein metabolic process; GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling; GO:0050727 regulation of inflammatory response; GO:0009967 positive regulation of signal transduction; GO:0043410 positive regulation of MAPK cascade; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0034774 secretory granule lumen; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0044444 cytoplasmic part; ","GO:0050786 RAGE receptor binding; GO:0046914 transition metal ion binding; GO:0005102 receptor binding; GO:0005488 binding; GO:0043167 ion binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0005509 calcium ion binding; GO:0005507 copper ion binding; GO:0008270 zinc ion binding; ",{"$nulls":3},"IPR002048; IPR011992; IPR013787; ","\"EF-hand domain; EF-hand domain pair; S100/CaBP-9k-type, calcium binding, subdomain; \"\r"]
["P82650","28S ribosomal protein S22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS22","MRPS22",41.28,13.616,12.5,4,4,4,0.997,0.929,0.941,1.044,0.974,1.118,1.094,0.123,"mitochondria\r","GO:0016043 cellular component organization; GO:0006518 peptide metabolic process; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:0043241 protein complex disassembly; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0043624 cellular protein complex disassembly; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006412 translation; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0071822 protein complex subunit organization; GO:0006414 translational elongation; GO:0043043 peptide biosynthetic process; GO:0044763 single-organism cellular process; GO:0032984 macromolecular complex disassembly; GO:0006807 nitrogen compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0032543 mitochondrial translation; GO:0070126 mitochondrial translational termination; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0006415 translational termination; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0070125 mitochondrial translational elongation; GO:0044260 cellular macromolecule metabolic process; GO:0022411 cellular component disassembly; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0071840 cellular component organization or biogenesis; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0015935 small ribosomal subunit; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0000313 organellar ribosome; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044391 ribosomal subunit; GO:0005622 intracellular; GO:0044464 cell part; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005840 ribosome; GO:0005759 mitochondrial matrix; GO:0000314 organellar small ribosomal subunit; GO:0044429 mitochondrial part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005761 mitochondrial ribosome; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005763 mitochondrial small ribosomal subunit; GO:0031975 envelope; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0003735 structural constituent of ribosome; GO:0005198 structural molecule activity; ","K17401"]
["P82921","28S ribosomal protein S21, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS21","MRPS21",10.688,14.632,13.8,1,2,1,0.859,0.85,0.882,1.065,1.152,1.178,1.31,1.16E-3,"extracellular\r","GO:0016043 cellular component organization; GO:0006518 peptide metabolic process; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:0043241 protein complex disassembly; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0043624 cellular protein complex disassembly; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006412 translation; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0071822 protein complex subunit organization; GO:0006414 translational elongation; GO:0043043 peptide biosynthetic process; GO:0044763 single-organism cellular process; GO:0032984 macromolecular complex disassembly; GO:0006807 nitrogen compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0032543 mitochondrial translation; GO:0070126 mitochondrial translational termination; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0006415 translational termination; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0070125 mitochondrial translational elongation; GO:0044260 cellular macromolecule metabolic process; GO:0022411 cellular component disassembly; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0071840 cellular component organization or biogenesis; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0015935 small ribosomal subunit; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0000313 organellar ribosome; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044391 ribosomal subunit; GO:0005622 intracellular; GO:0044464 cell part; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005840 ribosome; GO:0005759 mitochondrial matrix; GO:0000314 organellar small ribosomal subunit; GO:0044429 mitochondrial part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005761 mitochondrial ribosome; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005763 mitochondrial small ribosomal subunit; GO:0031975 envelope; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005198 structural molecule activity; GO:0003735 structural constituent of ribosome; ","K02970","RP-S21; small subunit ribosomal protein S21","hsa03010 Ribosome - Homo sapiens (human); "]
["P82970","High mobility group nucleosome-binding domain-containing protein 5 OS=Homo sapiens OX=9606 GN=HMGN5","HMGN5",31.524,2.3194,3.2,1,1,1,1.07,1.058,1.024,0.906,0.968,0.988,0.908,0.0296,"nucleus\r","GO:0010941 regulation of cell death; GO:0097659 nucleic acid-templated transcription; GO:0009891 positive regulation of biosynthetic process; GO:0009058 biosynthetic process; GO:0010564 regulation of cell cycle process; GO:0071157 negative regulation of cell cycle arrest; GO:0044237 cellular metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0051726 regulation of cell cycle; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0010948 negative regulation of cell cycle process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006325 chromatin organization; GO:0060548 negative regulation of cell death; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0045786 negative regulation of cell cycle; GO:0043069 negative regulation of programmed cell death; GO:0042127 regulation of cell proliferation; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0043067 regulation of programmed cell death; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:0043066 negative regulation of apoptotic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0016569 covalent chromatin modification; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0045787 positive regulation of cell cycle; GO:0071156 regulation of cell cycle arrest; GO:0051254 positive regulation of RNA metabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:0051252 regulation of RNA metabolic process; GO:1901576 organic substance biosynthetic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0051276 chromosome organization; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0010467 gene expression; GO:0043412 macromolecule modification; GO:0031328 positive regulation of cellular biosynthetic process; GO:0042981 regulation of apoptotic process; GO:0008284 positive regulation of cell proliferation; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0000785 chromatin; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0043227 membrane-bounded organelle; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003677 DNA binding; GO:0003723 RNA binding; GO:0031490 chromatin DNA binding; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0003676 nucleic acid binding; GO:0031491 nucleosome binding; GO:0003682 chromatin binding; GO:0031492 nucleosomal DNA binding; ","K17045"]
["P83436","Conserved oligomeric Golgi complex subunit 7 OS=Homo sapiens OX=9606 GN=COG7","COG7",86.343,4.0912,1.6,1,1,1,1.02,1.055,1.067,0.944,0.921,1.006,0.914,0.0374,"cytoplasm\r","GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0043413 macromolecule glycosylation; GO:0065008 regulation of biological quality; GO:0010256 endomembrane system organization; GO:0044267 cellular protein metabolic process; GO:0048193 Golgi vesicle transport; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:1901137 carbohydrate derivative biosynthetic process; GO:0006886 intracellular protein transport; GO:1901135 carbohydrate derivative metabolic process; GO:0033365 protein localization to organelle; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0034613 cellular protein localization; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0070085 glycosylation; GO:0006486 protein glycosylation; GO:0009101 glycoprotein biosynthetic process; GO:0034067 protein localization to Golgi apparatus; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0009100 glycoprotein metabolic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:0070727 cellular macromolecule localization; GO:0034645 cellular macromolecule biosynthetic process; GO:0007030 Golgi organization; GO:0006890 retrograde vesicle-mediated transport, Golgi to ER; GO:0006996 organelle organization; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0031647 regulation of protein stability; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:0051179 localization; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0050821 protein stabilization; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0032588 trans-Golgi network membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0098791 Golgi subcompartment; GO:0044431 Golgi apparatus part; GO:0017119 Golgi transport complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0099023 tethering complex; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0005802 trans-Golgi network; GO:0043234 protein complex; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; GO:0031984 organelle subcompartment; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0005488 binding; ","K20294"]
["P84077","ADP-ribosylation factor 1 OS=Homo sapiens OX=9606 GN=ARF1","ARF1",20.697,58.239,32,5,20,3,1.023,0.969,0.997,1.03,1.016,1.029,1.029,0.154,"cytoplasm\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0060627 regulation of vesicle-mediated transport; GO:0065008 regulation of biological quality; GO:0034379 very-low-density lipoprotein particle assembly; GO:0044255 cellular lipid metabolic process; GO:0031347 regulation of defense response; GO:0030832 regulation of actin filament length; GO:0019216 regulation of lipid metabolic process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0008610 lipid biosynthetic process; GO:0099003 vesicle-mediated transport in synapse; GO:0030036 actin cytoskeleton organization; GO:0008152 metabolic process; GO:0050690 regulation of defense response to virus by virus; GO:0051240 positive regulation of multicellular organismal process; GO:0065003 macromolecular complex assembly; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0032535 regulation of cellular component size; GO:0055065 metal ion homeostasis; GO:0071825 protein-lipid complex subunit organization; GO:0051493 regulation of cytoskeleton organization; GO:0008104 protein localization; GO:0044765 single-organism transport; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0048489 synaptic vesicle transport; GO:0006878 cellular copper ion homeostasis; GO:0051174 regulation of phosphorus metabolic process; GO:0048259 regulation of receptor-mediated endocytosis; GO:0045921 positive regulation of exocytosis; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0031346 positive regulation of cell projection organization; GO:0043269 regulation of ion transport; GO:0044763 single-organism cellular process; GO:0007264 small GTPase mediated signal transduction; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0046916 cellular transition metal ion homeostasis; GO:0034762 regulation of transmembrane transport; GO:0006810 transport; GO:0090407 organophosphate biosynthetic process; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; GO:0034377 plasma lipoprotein particle assembly; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:0050714 positive regulation of protein secretion; GO:0060999 positive regulation of dendritic spine development; GO:0051223 regulation of protein transport; GO:0002682 regulation of immune system process; GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II; GO:0051094 positive regulation of developmental process; GO:0097435 supramolecular fiber organization; GO:0010975 regulation of neuron projection development; GO:0051047 positive regulation of secretion; GO:1902903 regulation of supramolecular fiber organization; GO:0051640 organelle localization; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0044707 single-multicellular organism process; GO:0002028 regulation of sodium ion transport; GO:0097061 dendritic spine organization; GO:0034764 positive regulation of transmembrane transport; GO:0055076 transition metal ion homeostasis; GO:0006661 phosphatidylinositol biosynthetic process; GO:0032956 regulation of actin cytoskeleton organization; GO:1903725 regulation of phospholipid metabolic process; GO:0017157 regulation of exocytosis; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0051239 regulation of multicellular organismal process; GO:0045597 positive regulation of cell differentiation; GO:0060341 regulation of cellular localization; GO:1903335 regulation of vacuolar transport; GO:1900006 positive regulation of dendrite development; GO:0050688 regulation of defense response to virus; GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport; GO:0023057 negative regulation of signaling; GO:1902578 single-organism localization; GO:0010648 negative regulation of cell communication; GO:0010959 regulation of metal ion transport; GO:1902580 single-organism cellular localization; GO:0007275 multicellular organism development; GO:0032880 regulation of protein localization; GO:0007010 cytoskeleton organization; GO:1904062 regulation of cation transmembrane transport; GO:0048878 chemical homeostasis; GO:0048167 regulation of synaptic plasticity; GO:0030100 regulation of endocytosis; GO:0044711 single-organism biosynthetic process; GO:0051125 regulation of actin nucleation; GO:0048731 system development; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0016192 vesicle-mediated transport; GO:0043900 regulation of multi-organism process; GO:0050804 modulation of synaptic transmission; GO:0002376 immune system process; GO:0032101 regulation of response to external stimulus; GO:0071702 organic substance transport; GO:0032970 regulation of actin filament-based process; GO:1902824 positive regulation of late endosome to lysosome transport; GO:0051656 establishment of organelle localization; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0097480 establishment of synaptic vesicle localization; GO:0055070 copper ion homeostasis; GO:0045184 establishment of protein localization; GO:0043270 positive regulation of ion transport; GO:0008064 regulation of actin polymerization or depolymerization; GO:1904951 positive regulation of establishment of protein localization; GO:1904064 positive regulation of cation transmembrane transport; GO:0010976 positive regulation of neuron projection development; GO:0006873 cellular ion homeostasis; GO:0006793 phosphorus metabolic process; GO:0097479 synaptic vesicle localization; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0006900 membrane budding; GO:0030029 actin filament-based process; GO:0080171 lytic vacuole organization; GO:0019637 organophosphate metabolic process; GO:0050769 positive regulation of neurogenesis; GO:1902305 regulation of sodium ion transmembrane transport; GO:0006644 phospholipid metabolic process; GO:0006892 post-Golgi vesicle-mediated transport; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0097212 lysosomal membrane organization; GO:0030833 regulation of actin filament polymerization; GO:0045666 positive regulation of neuron differentiation; GO:0046486 glycerolipid metabolic process; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:0008654 phospholipid biosynthetic process; GO:0022008 neurogenesis; GO:0051046 regulation of secretion; GO:0044699 single-organism process; GO:0060292 long term synaptic depression; GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation; GO:0009058 biosynthetic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:1903307 positive regulation of regulated secretory pathway; GO:0022607 cellular component assembly; GO:0010765 positive regulation of sodium ion transport; GO:0060628 regulation of ER to Golgi vesicle-mediated transport; GO:0006650 glycerophospholipid metabolic process; GO:0032271 regulation of protein polymerization; GO:0046488 phosphatidylinositol metabolic process; GO:0007033 vacuole organization; GO:0010720 positive regulation of cell development; GO:0033036 macromolecule localization; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0002697 regulation of immune effector process; GO:0006629 lipid metabolic process; GO:0032502 developmental process; GO:0071827 plasma lipoprotein particle organization; GO:0051650 establishment of vesicle localization; GO:0050805 negative regulation of synaptic transmission; GO:0060998 regulation of dendritic spine development; GO:0050801 ion homeostasis; GO:0048002 antigen processing and presentation of peptide antigen; GO:0051962 positive regulation of nervous system development; GO:0098771 inorganic ion homeostasis; GO:0019725 cellular homeostasis; GO:0048522 positive regulation of cellular process; GO:0032386 regulation of intracellular transport; GO:1903530 regulation of secretion by cell; GO:0023052 signaling; GO:0002495 antigen processing and presentation of peptide antigen via MHC class II; GO:1902582 single-organism intracellular transport; GO:0007040 lysosome organization; GO:0051050 positive regulation of transport; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0043254 regulation of protein complex assembly; GO:0045956 positive regulation of calcium ion-dependent exocytosis; GO:0034767 positive regulation of ion transmembrane transport; GO:0045664 regulation of neuron differentiation; GO:1903532 positive regulation of secretion by cell; GO:0030030 cell projection organization; GO:0055108 Golgi to transport vesicle transport; GO:1902822 regulation of late endosome to lysosome transport; GO:0046474 glycerophospholipid biosynthetic process; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0065005 protein-lipid complex assembly; GO:0019220 regulation of phosphate metabolic process; GO:0048856 anatomical structure development; GO:0051222 positive regulation of protein transport; GO:2000026 regulation of multicellular organismal development; GO:1903337 positive regulation of vacuolar transport; GO:0016043 cellular component organization; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0002831 regulation of response to biotic stimulus; GO:0045807 positive regulation of endocytosis; GO:0060255 regulation of macromolecule metabolic process; GO:0030003 cellular cation homeostasis; GO:0048193 Golgi vesicle transport; GO:0007015 actin filament organization; GO:0031344 regulation of cell projection organization; GO:0044087 regulation of cellular component biogenesis; GO:0050896 response to stimulus; GO:0070201 regulation of establishment of protein localization; GO:0055082 cellular chemical homeostasis; GO:0071704 organic substance metabolic process; GO:0097006 regulation of plasma lipoprotein particle levels; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:0055080 cation homeostasis; GO:0051648 vesicle localization; GO:0050708 regulation of protein secretion; GO:0009987 cellular process; GO:0002090 regulation of receptor internalization; GO:0045595 regulation of cell differentiation; GO:0035556 intracellular signal transduction; GO:0051049 regulation of transport; GO:0032388 positive regulation of intracellular transport; GO:0050792 regulation of viral process; GO:0044802 single-organism membrane organization; GO:0016050 vesicle organization; GO:0033043 regulation of organelle organization; GO:1903305 regulation of regulated secretory pathway; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0043085 positive regulation of catalytic activity; GO:0045017 glycerolipid biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0019882 antigen processing and presentation; GO:0070142 synaptic vesicle budding; GO:0034765 regulation of ion transmembrane transport; GO:0044767 single-organism developmental process; GO:0050773 regulation of dendrite development; GO:0090066 regulation of anatomical structure size; GO:0006875 cellular metal ion homeostasis; GO:0051128 regulation of cellular component organization; GO:1902307 positive regulation of sodium ion transmembrane transport; GO:0017158 regulation of calcium ion-dependent exocytosis; GO:0050767 regulation of neurogenesis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044438 microbody part; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005778 peroxisomal membrane; GO:0070062 extracellular exosome; GO:0098590 plasma membrane region; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0098791 Golgi subcompartment; GO:0014069 postsynaptic density; GO:0097060 synaptic membrane; GO:0043005 neuron projection; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0005924 cell-substrate adherens junction; GO:0031252 cell leading edge; GO:0042995 cell projection; GO:0005770 late endosome; GO:0044439 peroxisomal part; GO:0070161 anchoring junction; GO:0005576 extracellular region; GO:0030135 coated vesicle; GO:0005798 Golgi-associated vesicle; GO:0099081 supramolecular polymer; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0098794 postsynapse; GO:0044449 contractile fiber part; GO:0099572 postsynaptic specialization; GO:0043230 extracellular organelle; GO:0031410 cytoplasmic vesicle; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0030016 myofibril; GO:0030137 COPI-coated vesicle; GO:0031982 vesicle; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0032279 asymmetric synapse; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0042579 microbody; GO:0043292 contractile fiber; GO:1903561 extracellular vesicle; GO:0005912 adherens junction; GO:0044431 Golgi apparatus part; GO:0048471 perinuclear region of cytoplasm; GO:0005768 endosome; GO:0098984 neuron to neuron synapse; GO:0044456 synapse part; GO:0031903 microbody membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005777 peroxisome; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0045202 synapse; GO:0045211 postsynaptic membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0030017 sarcomere; GO:0005802 trans-Golgi network; GO:0005794 Golgi apparatus; GO:0031984 organelle subcompartment; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0016004 phospholipase activator activity; GO:0004871 signal transducer activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0019003 GDP binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0003924 GTPase activity; GO:0032550 purine ribonucleoside binding; GO:0060229 lipase activator activity; GO:0043169 cation binding; GO:1990583 phospholipase D activator activity; GO:0043168 anion binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0008047 enzyme activator activity; GO:0035639 purine ribonucleoside triphosphate binding; GO:0017076 purine nucleotide binding; GO:0000287 magnesium ion binding; GO:0003723 RNA binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0005057 signal transducer activity, downstream of receptor; GO:0097367 carbohydrate derivative binding; GO:0030234 enzyme regulator activity; GO:0003676 nucleic acid binding; GO:0046872 metal ion binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0032561 guanyl ribonucleotide binding; GO:0036094 small molecule binding; ","K07937","ARF1; ADP-ribosylation factor 1","hsa05110 Vibrio cholerae infection - Homo sapiens (human); hsa05134 Legionellosis - Homo sapiens (human); hsa04072 Phospholipase D signaling pathway - Homo sapiens (human); hsa04144 Endocytosis - Homo sapiens (human); ","IPR005225; IPR027417; ","Small GTP-binding protein domain; P-loop containing nucleoside triphosphate hydrolase; \r"]
["P84090","Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH","ERH",12.259,23.875,34.6,4,5,4,1.009,0.892,0.886,1.067,1.12,1.09,1.176,0.0213,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0009116 nucleoside metabolic process; GO:0045747 positive regulation of Notch signaling pathway; GO:0009165 nucleotide biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0009117 nucleotide metabolic process; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0006221 pyrimidine nucleotide biosynthetic process; GO:0009058 biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0072528 pyrimidine-containing compound biosynthetic process; GO:0008152 metabolic process; GO:0010646 regulation of cell communication; GO:0046483 heterocycle metabolic process; GO:0006213 pyrimidine nucleoside metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0023056 positive regulation of signaling; GO:1901135 carbohydrate derivative metabolic process; GO:0072527 pyrimidine-containing compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0010647 positive regulation of cell communication; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0009966 regulation of signal transduction; GO:0018130 heterocycle biosynthetic process; GO:0044711 single-organism biosynthetic process; GO:0044281 small molecule metabolic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0044763 single-organism cellular process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0090407 organophosphate biosynthetic process; GO:0008593 regulation of Notch signaling pathway; GO:0006220 pyrimidine nucleotide metabolic process; GO:0050789 regulation of biological process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:0019637 organophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0009967 positive regulation of signal transduction; GO:0048584 positive regulation of response to stimulus; GO:0007049 cell cycle; GO:1901362 organic cyclic compound biosynthetic process; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:1902494 catalytic complex; GO:0034709 methylosome; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0030496 midbody; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:1990234 transferase complex; GO:0005623 cell; GO:0044444 cytoplasmic part; GO:0034708 methyltransferase complex; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003677 DNA binding; GO:0003723 RNA binding; GO:1901265 nucleoside phosphate binding; GO:0008327 methyl-CpG binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0043565 sequence-specific DNA binding; GO:0036094 small molecule binding; "]
["P84103","Serine/arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3","SRSF3",19.329,11.957,27.4,5,11,4,0.878,0.96,0.92,1.049,1.024,1.106,1.153,0.0144,"nucleus\r","GO:0050658 RNA transport; GO:0097659 nucleic acid-templated transcription; GO:0009058 biosynthetic process; GO:0051168 nuclear export; GO:0051169 nuclear transport; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006353 DNA-templated transcription, termination; GO:0071427 mRNA-containing ribonucleoprotein complex export from nucleus; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0050657 nucleic acid transport; GO:0015931 nucleobase-containing compound transport; GO:0043170 macromolecule metabolic process; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0048024 regulation of mRNA splicing, via spliceosome; GO:0006396 RNA processing; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0050684 regulation of mRNA processing; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0006611 protein export from nucleus; GO:0071166 ribonucleoprotein complex localization; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006913 nucleocytoplasmic transport; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0050794 regulation of cellular process; GO:0031123 RNA 3'-end processing; GO:0046907 intracellular transport; GO:0006725 cellular aromatic compound metabolic process; GO:0031124 mRNA 3'-end processing; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0051028 mRNA transport; GO:0051236 establishment of RNA localization; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0006886 intracellular protein transport; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034613 cellular protein localization; GO:0009059 macromolecule biosynthetic process; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0006406 mRNA export from nucleus; GO:0006369 termination of RNA polymerase II transcription; GO:0006403 RNA localization; GO:0006405 RNA export from nucleus; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0051252 regulation of RNA metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0043484 regulation of RNA splicing; GO:0045184 establishment of protein localization; GO:1903311 regulation of mRNA metabolic process; GO:0070727 cellular macromolecule localization; GO:0034645 cellular macromolecule biosynthetic process; GO:0071426 ribonucleoprotein complex export from nucleus; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006366 transcription from RNA polymerase II promoter; GO:0010467 gene expression; GO:0051179 localization; GO:0071705 nitrogen compound transport; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031974 membrane-enclosed lumen; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003729 mRNA binding; GO:0003723 RNA binding; GO:1901265 nucleoside phosphate binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:1990825 sequence-specific mRNA binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0036094 small molecule binding; ","K12892","SFRS3; splicing factor, arginine/serine-rich 3","hsa03040 Spliceosome - Homo sapiens (human); hsa05168 Herpes simplex infection - Homo sapiens (human); ","IPR000504; IPR012677; ","RNA recognition motif domain; Nucleotide-binding alpha-beta plait domain; \r"]
["P85037","Forkhead box protein K1 OS=Homo sapiens OX=9606 GN=FOXK1","FOXK1",75.456,5.4747,4.6,4,4,4,0.814,1.139,1.123,1.175,0.937,0.83,0.956,0.786,"nucleus\r","GO:0070646 protein modification by small protein removal; GO:0097659 nucleic acid-templated transcription; GO:0048869 cellular developmental process; GO:0009891 positive regulation of biosynthetic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0051253 negative regulation of RNA metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0007517 muscle organ development; GO:1902679 negative regulation of RNA biosynthetic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006464 cellular protein modification process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0048523 negative regulation of cellular process; GO:0016579 protein deubiquitination; GO:0071704 organic substance metabolic process; GO:0045892 negative regulation of transcription, DNA-templated; GO:0030154 cell differentiation; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0061061 muscle structure development; GO:0006508 proteolysis; GO:1902680 positive regulation of RNA biosynthetic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0009059 macromolecule biosynthetic process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0009987 cellular process; GO:0051254 positive regulation of RNA metabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0048731 system development; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0009892 negative regulation of metabolic process; GO:0051252 regulation of RNA metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0009890 negative regulation of biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0044767 single-organism developmental process; GO:0031325 positive regulation of cellular metabolic process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0010467 gene expression; GO:0031327 negative regulation of cellular biosynthetic process; GO:0043412 macromolecule modification; GO:0031328 positive regulation of cellular biosynthetic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding; GO:0003677 DNA binding; GO:0000976 transcription regulatory region sequence-specific DNA binding; GO:0003690 double-stranded DNA binding; GO:1990837 sequence-specific double-stranded DNA binding; GO:0001012 RNA polymerase II regulatory region DNA binding; GO:0005515 protein binding; GO:0043565 sequence-specific DNA binding; GO:0003700 transcription factor activity, sequence-specific DNA binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0000975 regulatory region DNA binding; GO:0001067 regulatory region nucleic acid binding; GO:0005488 binding; GO:0044212 transcription regulatory region DNA binding; GO:0003676 nucleic acid binding; GO:0001071 nucleic acid binding transcription factor activity; GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding; ","K09404",null,null,"IPR011991; IPR008984; IPR001766; IPR000253; ","Winged helix-turn-helix DNA-binding domain; SMAD/FHA domain; Fork head domain; Forkhead-associated (FHA) domain; \r"]
["P98082","Disabled homolog 2 OS=Homo sapiens OX=9606 GN=DAB2","DAB2",82.447,17.672,5.8,4,6,4,1.066,1.107,1.048,0.859,1.009,0.869,0.85,0.0382,"nucleus\r","GO:0044700 single organism signaling; GO:0060627 regulation of vesicle-mediated transport; GO:0010941 regulation of cell death; GO:0030335 positive regulation of cell migration; GO:0010717 regulation of epithelial to mesenchymal transition; GO:0032270 positive regulation of cellular protein metabolic process; GO:0007166 cell surface receptor signaling pathway; GO:1903533 regulation of protein targeting; GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0009891 positive regulation of biosynthetic process; GO:0060766 negative regulation of androgen receptor signaling pathway; GO:0032091 negative regulation of protein binding; GO:0015031 protein transport; GO:1903729 regulation of plasma membrane organization; GO:1903364 positive regulation of cellular protein catabolic process; GO:0090100 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; GO:1903651 positive regulation of cytoplasmic transport; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0016055 Wnt signaling pathway; GO:0008104 protein localization; GO:1903362 regulation of cellular protein catabolic process; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0051174 regulation of phosphorus metabolic process; GO:0048259 regulation of receptor-mediated endocytosis; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0060765 regulation of androgen receptor signaling pathway; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0060828 regulation of canonical Wnt signaling pathway; GO:0090287 regulation of cellular response to growth factor stimulus; GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation; GO:0051272 positive regulation of cellular component movement; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:1903506 regulation of nucleic acid-templated transcription; GO:0007267 cell-cell signaling; GO:0048583 regulation of response to stimulus; GO:0061136 regulation of proteasomal protein catabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051223 regulation of protein transport; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0051094 positive regulation of developmental process; GO:0060548 negative regulation of cell death; GO:0042307 positive regulation of protein import into nucleus; GO:0030855 epithelial cell differentiation; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0031399 regulation of protein modification process; GO:1903076 regulation of protein localization to plasma membrane; GO:2000370 positive regulation of clathrin-dependent endocytosis; GO:0043067 regulation of programmed cell death; GO:0033144 negative regulation of intracellular steroid hormone receptor signaling pathway; GO:2000147 positive regulation of cell motility; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0045597 positive regulation of cell differentiation; GO:0051239 regulation of multicellular organismal process; GO:0060341 regulation of cellular localization; GO:0045892 negative regulation of transcription, DNA-templated; GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0035026 leading edge cell differentiation; GO:0060390 regulation of SMAD protein import into nucleus; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:2000145 regulation of cell motility; GO:0009896 positive regulation of catabolic process; GO:2000641 regulation of early endosome to late endosome transport; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0007275 multicellular organism development; GO:0006898 receptor-mediated endocytosis; GO:0032880 regulation of protein localization; GO:0042176 regulation of protein catabolic process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0009966 regulation of signal transduction; GO:0051254 positive regulation of RNA metabolic process; GO:0030100 regulation of endocytosis; GO:0051270 regulation of cellular component movement; GO:0016192 vesicle-mediated transport; GO:0008283 cell proliferation; GO:0071702 organic substance transport; GO:0030334 regulation of cell migration; GO:0030162 regulation of proteolysis; GO:0009892 negative regulation of metabolic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0045184 establishment of protein localization; GO:1900182 positive regulation of protein localization to nucleus; GO:0009890 negative regulation of biosynthetic process; GO:0051247 positive regulation of protein metabolic process; GO:1904951 positive regulation of establishment of protein localization; GO:0046822 regulation of nucleocytoplasmic transport; GO:0010718 positive regulation of epithelial to mesenchymal transition; GO:0030111 regulation of Wnt signaling pathway; GO:0061024 membrane organization; GO:0031325 positive regulation of cellular metabolic process; GO:0030177 positive regulation of Wnt signaling pathway; GO:0012501 programmed cell death; GO:0031328 positive regulation of cellular biosynthetic process; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway; GO:1904591 positive regulation of protein import; GO:1903827 regulation of cellular protein localization; GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process; GO:0009968 negative regulation of signal transduction; GO:0040017 positive regulation of locomotion; GO:0031331 positive regulation of cellular catabolic process; GO:0023051 regulation of signaling; GO:0051129 negative regulation of cellular component organization; GO:0048869 cellular developmental process; GO:0090090 negative regulation of canonical Wnt signaling pathway; GO:0044699 single-organism process; GO:2000050 regulation of non-canonical Wnt signaling pathway; GO:0051253 negative regulation of RNA metabolic process; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:1905330 regulation of morphogenesis of an epithelium; GO:2001141 regulation of RNA biosynthetic process; GO:0042306 regulation of protein import into nucleus; GO:0007165 signal transduction; GO:1904375 regulation of protein localization to cell periphery; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0006915 apoptotic process; GO:0046824 positive regulation of nucleocytoplasmic transport; GO:0033036 macromolecule localization; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:2000643 positive regulation of early endosome to late endosome transport; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0010468 regulation of gene expression; GO:1905476 negative regulation of protein localization to membrane; GO:1903828 negative regulation of cellular protein localization; GO:0045937 positive regulation of phosphate metabolic process; GO:0009888 tissue development; GO:0030178 negative regulation of Wnt signaling pathway; GO:0031326 regulation of cellular biosynthetic process; GO:1903846 positive regulation of cellular response to transforming growth factor beta stimulus; GO:1903649 regulation of cytoplasmic transport; GO:0051098 regulation of binding; GO:0048522 positive regulation of cellular process; GO:0032386 regulation of intracellular transport; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0198738 cell-cell signaling by wnt; GO:0051050 positive regulation of transport; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0051100 negative regulation of binding; GO:1902679 negative regulation of RNA biosynthetic process; GO:1900180 regulation of protein localization to nucleus; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:2000369 regulation of clathrin-dependent endocytosis; GO:0033143 regulation of intracellular steroid hormone receptor signaling pathway; GO:0048856 anatomical structure development; GO:0051222 positive regulation of protein transport; GO:0048260 positive regulation of receptor-mediated endocytosis; GO:2000026 regulation of multicellular organismal development; GO:0016043 cellular component organization; GO:0090175 regulation of establishment of planar polarity; GO:0043069 negative regulation of programmed cell death; GO:0090316 positive regulation of intracellular protein transport; GO:1903829 positive regulation of cellular protein localization; GO:0060255 regulation of macromolecule metabolic process; GO:0045807 positive regulation of endocytosis; GO:0017015 regulation of transforming growth factor beta receptor signaling pathway; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:1904376 negative regulation of protein localization to cell periphery; GO:1904589 regulation of protein import; GO:2000052 positive regulation of non-canonical Wnt signaling pathway; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0070201 regulation of establishment of protein localization; GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0043393 regulation of protein binding; GO:1903077 negative regulation of protein localization to plasma membrane; GO:1905475 regulation of protein localization to membrane; GO:0030154 cell differentiation; GO:0045862 positive regulation of proteolysis; GO:2000027 regulation of organ morphogenesis; GO:0060393 regulation of pathway-restricted SMAD protein phosphorylation; GO:0043066 negative regulation of apoptotic process; GO:0023056 positive regulation of signaling; GO:0010647 positive regulation of cell communication; GO:0033157 regulation of intracellular protein transport; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0032388 positive regulation of intracellular transport; GO:0051049 regulation of transport; GO:0001932 regulation of protein phosphorylation; GO:1901800 positive regulation of proteasomal protein catabolic process; GO:0031401 positive regulation of protein modification process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0001934 positive regulation of protein phosphorylation; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:1903844 regulation of cellular response to transforming growth factor beta stimulus; GO:0060391 positive regulation of SMAD protein import into nucleus; GO:0008219 cell death; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0009967 positive regulation of signal transduction; GO:0045732 positive regulation of protein catabolic process; GO:0051128 regulation of cellular component organization; GO:0031327 negative regulation of cellular biosynthetic process; GO:0040012 regulation of locomotion; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0030662 coated vesicle membrane; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005765 lysosomal membrane; GO:0070062 extracellular exosome; GO:0070013 intracellular organelle lumen; GO:0005925 focal adhesion; GO:0030136 clathrin-coated vesicle; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005764 lysosome; GO:0098589 membrane region; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0005924 cell-substrate adherens junction; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0031981 nuclear lumen; GO:0044452 nucleolar part; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0030665 clathrin-coated vesicle membrane; GO:0001650 fibrillar center; GO:0030135 coated vesicle; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0005905 clathrin-coated pit; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0098748 endocytic adaptor activity; GO:0030276 clathrin binding; GO:0060089 molecular transducer activity; GO:0030674 protein binding, bridging; GO:0004872 receptor activity; GO:0005488 binding; GO:0038024 cargo receptor activity; GO:0060090 binding, bridging; GO:0005515 protein binding; GO:0008022 protein C-terminus binding; GO:0035615 clathrin adaptor activity; GO:0046332 SMAD binding; ","K12475","DAB2; disabled homolog 2","hsa04144 Endocytosis - Homo sapiens (human); ","IPR011993; IPR006020; ","PH domain-like; PTB/PI domain; \r"]
["P98175","RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10","RBM10",103.53,4.9368,2.7,2,3,2,1.112,0.951,1.108,0.84,0.941,1.055,0.894,0.246,"nucleus\r","GO:0050794 regulation of cellular process; GO:0010941 regulation of cell death; GO:0000381 regulation of alternative mRNA splicing, via spliceosome; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0043067 regulation of programmed cell death; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0048024 regulation of mRNA splicing, via spliceosome; GO:0006396 RNA processing; GO:0010468 regulation of gene expression; GO:0080090 regulation of primary metabolic process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0050684 regulation of mRNA processing; GO:0044238 primary metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:0043484 regulation of RNA splicing; GO:1903311 regulation of mRNA metabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0010467 gene expression; GO:0016071 mRNA metabolic process; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031974 membrane-enclosed lumen; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0003723 RNA binding; GO:1901265 nucleoside phosphate binding; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0008270 zinc ion binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0042802 identical protein binding; GO:0046914 transition metal ion binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0032403 protein complex binding; GO:0036094 small molecule binding; ","K13094",null,null,"IPR000504; IPR012677; IPR007087; IPR000467; IPR001876; ","\"RNA recognition motif domain; Nucleotide-binding alpha-beta plait domain; Zinc finger, C2H2; G-patch domain; Zinc finger, RanBP2-type; \"\r"]
["P99999","Cytochrome c OS=Homo sapiens OX=9606 GN=CYCS","CYCS",11.749,39.54,45.7,6,14,6,0.996,1.022,1.038,0.968,1.068,0.926,0.969,0.495,"mitochondria\r","GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0032270 positive regulation of cellular protein metabolic process; GO:0006123 mitochondrial electron transport, cytochrome c to oxygen; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0007154 cell communication; GO:0006091 generation of precursor metabolites and energy; GO:0009893 positive regulation of metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0044093 positive regulation of molecular function; GO:0007005 mitochondrion organization; GO:0006915 apoptotic process; GO:0006979 response to oxidative stress; GO:0019693 ribose phosphate metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0052548 regulation of endopeptidase activity; GO:0051716 cellular response to stimulus; GO:0010950 positive regulation of endopeptidase activity; GO:0080090 regulation of primary metabolic process; GO:2000116 regulation of cysteine-type endopeptidase activity; GO:0055114 oxidation-reduction process; GO:0000302 response to reactive oxygen species; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006119 oxidative phosphorylation; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0023052 signaling; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0010942 positive regulation of cell death; GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0051336 regulation of hydrolase activity; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0044260 cellular macromolecule metabolic process; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0022900 electron transport chain; GO:0006464 cellular protein modification process; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0052547 regulation of peptidase activity; GO:0036211 protein modification process; GO:0010952 positive regulation of peptidase activity; GO:0043068 positive regulation of programmed cell death; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0016310 phosphorylation; GO:0097190 apoptotic signaling pathway; GO:2001056 positive regulation of cysteine-type endopeptidase activity; GO:0006725 cellular aromatic compound metabolic process; GO:0042773 ATP synthesis coupled electron transport; GO:0060255 regulation of macromolecule metabolic process; GO:0009259 ribonucleotide metabolic process; GO:0043067 regulation of programmed cell death; GO:1901700 response to oxygen-containing compound; GO:0044267 cellular protein metabolic process; GO:0043065 positive regulation of apoptotic process; GO:0022904 respiratory electron transport chain; GO:0050896 response to stimulus; GO:0097193 intrinsic apoptotic signaling pathway; GO:0071704 organic substance metabolic process; GO:0045862 positive regulation of proteolysis; GO:0046483 heterocycle metabolic process; GO:0051345 positive regulation of hydrolase activity; GO:0006139 nucleobase-containing compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009119 ribonucleoside metabolic process; GO:0009987 cellular process; GO:0046034 ATP metabolic process; GO:0006950 response to stress; GO:0035556 intracellular signal transduction; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0006470 protein dephosphorylation; GO:0048518 positive regulation of biological process; GO:0045333 cellular respiration; GO:0016311 dephosphorylation; GO:0006163 purine nucleotide metabolic process; GO:0043085 positive regulation of catalytic activity; GO:0046128 purine ribonucleoside metabolic process; GO:0051247 positive regulation of protein metabolic process; GO:0008219 cell death; GO:0006793 phosphorus metabolic process; GO:0051246 regulation of protein metabolic process; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0019637 organophosphate metabolic process; GO:0012501 programmed cell death; GO:0009150 purine ribonucleotide metabolic process; GO:0043412 macromolecule modification; GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0008287 protein serine/threonine phosphatase complex; GO:0044424 intracellular part; GO:0005623 cell; GO:1903293 phosphatase complex; GO:0044422 organelle part; GO:0000159 protein phosphatase type 2A complex; GO:0031974 membrane-enclosed lumen; GO:0005740 mitochondrial envelope; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0031970 organelle envelope lumen; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005829 cytosol; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005758 mitochondrial intermembrane space; GO:0031975 envelope; GO:0070469 respiratory chain; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0009055 electron carrier activity; GO:0020037 heme binding; GO:0005488 binding; GO:0043167 ion binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity; GO:0005515 protein binding; GO:0046906 tetrapyrrole binding; ","K08738","CYC; cytochrome c","hsa05010 Alzheimer's disease - Homo sapiens (human); hsa05152 Tuberculosis - Homo sapiens (human); hsa04210 Apoptosis - Homo sapiens (human); hsa05168 Herpes simplex infection - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa04115 p53 signaling pathway - Homo sapiens (human); hsa05167 Kaposi's sarcoma-associated herpesvirus infection - Homo sapiens (human); hsa05222 Small cell lung cancer - Homo sapiens (human); hsa05134 Legionellosis - Homo sapiens (human); hsa05145 Toxoplasmosis - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); hsa05164 Influenza A - Homo sapiens (human); hsa01524 Platinum drug resistance - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa00920 Sulfur metabolism - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa05014 Amyotrophic lateral sclerosis (ALS) - Homo sapiens (human); hsa05416 Viral myocarditis - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa05161 Hepatitis B - Homo sapiens (human); hsa04215 Apoptosis - multiple species - Homo sapiens (human); hsa05210 Colorectal cancer - Homo sapiens (human); ","IPR009056; ","Cytochrome c-like domain; \r"]
["Q00169","Phosphatidylinositol transfer protein alpha isoform OS=Homo sapiens OX=9606 GN=PITPNA","PITPNA",31.806,69.238,39.6,11,19,11,0.944,0.939,0.984,1.055,1.074,1.041,1.106,0.0044,"cytoplasm\r","GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0007601 visual perception; GO:0048869 cellular developmental process; GO:0048666 neuron development; GO:0044699 single-organism process; GO:0032989 cellular component morphogenesis; GO:0022008 neurogenesis; GO:0048468 cell development; GO:0050877 neurological system process; GO:0071704 organic substance metabolic process; GO:0000904 cell morphogenesis involved in differentiation; GO:0051234 establishment of localization; GO:0009653 anatomical structure morphogenesis; GO:0008152 metabolic process; GO:0030154 cell differentiation; GO:1902578 single-organism localization; GO:0032990 cell part morphogenesis; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0007409 axonogenesis; GO:0048858 cell projection morphogenesis; GO:0007275 multicellular organism development; GO:0033036 macromolecule localization; GO:0009987 cellular process; GO:0006629 lipid metabolic process; GO:0044765 single-organism transport; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0007600 sensory perception; GO:0006869 lipid transport; GO:0003008 system process; GO:0048699 generation of neurons; GO:0048731 system development; GO:0044763 single-organism cellular process; GO:0071702 organic substance transport; GO:0010876 lipid localization; GO:0048812 neuron projection morphogenesis; GO:0015914 phospholipid transport; GO:0050953 sensory perception of light stimulus; GO:0044238 primary metabolic process; GO:0031175 neuron projection development; GO:0032501 multicellular organismal process; GO:0006820 anion transport; GO:0006810 transport; GO:0000902 cell morphogenesis; GO:0015748 organophosphate ester transport; GO:0030182 neuron differentiation; GO:0061564 axon development; GO:0015711 organic anion transport; GO:0030030 cell projection organization; GO:0044710 single-organism metabolic process; GO:0006811 ion transport; GO:0044767 single-organism developmental process; GO:0051179 localization; GO:0048856 anatomical structure development; GO:0071840 cellular component organization or biogenesis; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0005622 intracellular; GO:0043209 myelin sheath; GO:0044464 cell part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:0070405 ammonium ion binding; GO:0043167 ion binding; GO:0005319 lipid transporter activity; GO:0022892 substrate-specific transporter activity; GO:0008526 phosphatidylinositol transporter activity; GO:1901611 phosphatidylglycerol binding; GO:0031210 phosphatidylcholine binding; GO:0050997 quaternary ammonium group binding; GO:0005488 binding; GO:0005543 phospholipid binding; GO:0035091 phosphatidylinositol binding; GO:0008289 lipid binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0008525 phosphatidylcholine transporter activity; GO:0005548 phospholipid transporter activity; GO:0005215 transporter activity; ",{"$nulls":3},"IPR023393; ","START-like domain; \r"]
["Q00341","Vigilin OS=Homo sapiens OX=9606 GN=HDLBP","HDLBP",141.45,75.503,18.8,23,37,23,1.02,1.019,1.052,1.013,0.949,0.972,0.949,0.0736,"cytoplasm\r","GO:0008203 cholesterol metabolic process; GO:0006869 lipid transport; GO:1901615 organic hydroxy compound metabolic process; GO:1902652 secondary alcohol metabolic process; GO:0006066 alcohol metabolic process; GO:0044281 small molecule metabolic process; GO:0008202 steroid metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0044699 single-organism process; GO:0071702 organic substance transport; GO:0010876 lipid localization; GO:0044238 primary metabolic process; GO:0016125 sterol metabolic process; GO:0042157 lipoprotein metabolic process; GO:0051234 establishment of localization; GO:0071704 organic substance metabolic process; GO:0006810 transport; GO:0008152 metabolic process; GO:1902578 single-organism localization; GO:0044710 single-organism metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0051179 localization; GO:0033036 macromolecule localization; GO:0044765 single-organism transport; GO:0006629 lipid metabolic process; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005615 extracellular space; GO:0071944 cell periphery; GO:0034358 plasma lipoprotein particle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0034364 high-density lipoprotein particle; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0032994 protein-lipid complex; GO:0005622 intracellular; GO:0044464 cell part; GO:1990777 lipoprotein particle; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0050839 cell adhesion molecule binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0003676 nucleic acid binding; GO:0008289 lipid binding; GO:0005515 protein binding; ",{"$nulls":3},"IPR004087; IPR004088; ","\"K Homology domain; K Homology domain, type 1; \"\r"]
["Q00577","Transcriptional activator protein Pur-alpha OS=Homo sapiens OX=9606 GN=PURA","PURA",34.91,69.848,28,7,14,7,1.09,1.099,1.021,0.965,0.94,0.946,0.888,0.00864,"cytoplasm\r","GO:0006268 DNA unwinding involved in DNA replication; GO:0097659 nucleic acid-templated transcription; GO:0010608 posttranscriptional regulation of gene expression; GO:0048869 cellular developmental process; GO:0032392 DNA geometric change; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0051253 negative regulation of RNA metabolic process; GO:0044237 cellular metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0043170 macromolecule metabolic process; GO:0006261 DNA-dependent DNA replication; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0071103 DNA conformation change; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0034249 negative regulation of cellular amide metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0032501 multicellular organismal process; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0032269 negative regulation of cellular protein metabolic process; GO:1902679 negative regulation of RNA biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0048856 anatomical structure development; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0006260 DNA replication; GO:0042127 regulation of cell proliferation; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0006259 DNA metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0017148 negative regulation of translation; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0045892 negative regulation of transcription, DNA-templated; GO:0030154 cell differentiation; GO:0006270 DNA replication initiation; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0009059 macromolecule biosynthetic process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0048731 system development; GO:0032508 DNA duplex unwinding; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0009892 negative regulation of metabolic process; GO:0051252 regulation of RNA metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0034248 regulation of cellular amide metabolic process; GO:0009890 negative regulation of biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0051276 chromosome organization; GO:0006417 regulation of translation; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0006996 organelle organization; GO:0051248 negative regulation of protein metabolic process; GO:0010467 gene expression; GO:0031327 negative regulation of cellular biosynthetic process; GO:0008284 positive regulation of cell proliferation; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0030425 dendrite; GO:0000784 nuclear chromosome, telomeric region; GO:0000781 chromosome, telomeric region; GO:0043601 nuclear replisome; GO:0005737 cytoplasm; GO:0043025 neuronal cell body; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044454 nuclear chromosome part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0030894 replisome; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0032993 protein-DNA complex; GO:0005662 DNA replication factor A complex; GO:0043233 organelle lumen; GO:0005657 replication fork; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0043596 nuclear replication fork; GO:0043231 intracellular membrane-bounded organelle; GO:0098687 chromosomal region; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0005634 nucleus; GO:0000228 nuclear chromosome; GO:0044297 cell body; GO:0043234 protein complex; GO:0044428 nuclear part; ","GO:0003691 double-stranded telomeric DNA binding; GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding; GO:0003723 RNA binding; GO:0003677 DNA binding; GO:0090079 translation regulator activity, nucleic acid binding; GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding; GO:0003690 double-stranded DNA binding; GO:1990837 sequence-specific double-stranded DNA binding; GO:0003697 single-stranded DNA binding; GO:0000900 translation repressor activity, nucleic acid binding; GO:0042162 telomeric DNA binding; GO:0005515 protein binding; GO:0045182 translation regulator activity; GO:0043565 sequence-specific DNA binding; GO:0030371 translation repressor activity; GO:0003700 transcription factor activity, sequence-specific DNA binding; GO:0032422 purine-rich negative regulatory element binding; GO:0000975 regulatory region DNA binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0001067 regulatory region nucleic acid binding; GO:0044212 transcription regulatory region DNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0001071 nucleic acid binding transcription factor activity; GO:0046332 SMAD binding; GO:0008134 transcription factor binding; "]
["Q00610","Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC","CLTC",191.61,323.31,41.9,61,128,61,1.032,1.015,1.021,0.981,0.983,0.982,0.96,0.0143,"cytoplasm\r","GO:0044700 single organism signaling; GO:0001649 osteoblast differentiation; GO:0032885 regulation of polysaccharide biosynthetic process; GO:0007166 cell surface receptor signaling pathway; GO:0006914 autophagy; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:1900126 negative regulation of hyaluronan biosynthetic process; GO:0000041 transition metal ion transport; GO:1903729 regulation of plasma membrane organization; GO:0008152 metabolic process; GO:0032879 regulation of localization; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0051493 regulation of cytoskeleton organization; GO:0043170 macromolecule metabolic process; GO:0016055 Wnt signaling pathway; GO:0008104 protein localization; GO:0044765 single-organism transport; GO:0051716 cellular response to stimulus; GO:0000278 mitotic cell cycle; GO:0080090 regulation of primary metabolic process; GO:0001503 ossification; GO:0007088 regulation of mitotic nuclear division; GO:0044763 single-organism cellular process; GO:0033572 transferrin transport; GO:0032501 multicellular organismal process; GO:0032886 regulation of microtubule-based process; GO:0006810 transport; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; GO:0007267 cell-cell signaling; GO:0042147 retrograde transport, endosome to Golgi; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0060071 Wnt signaling pathway, planar cell polarity pathway; GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II; GO:0051301 cell division; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0044707 single-multicellular organism process; GO:0043255 regulation of carbohydrate biosynthetic process; GO:0007346 regulation of mitotic cell cycle; GO:0030001 metal ion transport; GO:1903076 regulation of protein localization to plasma membrane; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0051239 regulation of multicellular organismal process; GO:0060341 regulation of cellular localization; GO:1902578 single-organism localization; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0044248 cellular catabolic process; GO:0032880 regulation of protein localization; GO:0006898 receptor-mediated endocytosis; GO:0034613 cellular protein localization; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0071702 organic substance transport; GO:0006109 regulation of carbohydrate metabolic process; GO:0007017 microtubule-based process; GO:0009892 negative regulation of metabolic process; GO:0072512 trivalent inorganic cation transport; GO:0045184 establishment of protein localization; GO:0009890 negative regulation of biosynthetic process; GO:0045912 negative regulation of carbohydrate metabolic process; GO:0090224 regulation of spindle organization; GO:0006811 ion transport; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0006928 movement of cell or subcellular component; GO:0000280 nuclear division; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:1903827 regulation of cellular protein localization; GO:0031623 receptor internalization; GO:0048869 cellular developmental process; GO:0007067 mitotic nuclear division; GO:0051129 negative regulation of cellular component organization; GO:0044699 single-organism process; GO:0060236 regulation of mitotic spindle organization; GO:0051234 establishment of localization; GO:0035567 non-canonical Wnt signaling pathway; GO:1905330 regulation of morphogenesis of an epithelium; GO:0051783 regulation of nuclear division; GO:1904375 regulation of protein localization to cell periphery; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:1900125 regulation of hyaluronan biosynthetic process; GO:0033036 macromolecule localization; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0051726 regulation of cell cycle; GO:0032502 developmental process; GO:1905476 negative regulation of protein localization to membrane; GO:1903828 negative regulation of cellular protein localization; GO:0043112 receptor metabolic process; GO:0015682 ferric iron transport; GO:0048002 antigen processing and presentation of peptide antigen; GO:0023052 signaling; GO:0002495 antigen processing and presentation of peptide antigen via MHC class II; GO:0010605 negative regulation of macromolecule metabolic process; GO:0198738 cell-cell signaling by wnt; GO:0016197 endosomal transport; GO:0050789 regulation of biological process; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0019222 regulation of metabolic process; GO:2000026 regulation of multicellular organismal development; GO:0016043 cellular component organization; GO:0090175 regulation of establishment of planar polarity; GO:0060255 regulation of macromolecule metabolic process; GO:0048285 organelle fission; GO:1904376 negative regulation of protein localization to cell periphery; GO:0006826 iron ion transport; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:1903077 negative regulation of protein localization to plasma membrane; GO:0030154 cell differentiation; GO:1905475 regulation of protein localization to membrane; GO:2000027 regulation of organ morphogenesis; GO:0006812 cation transport; GO:0006886 intracellular protein transport; GO:0016482 cytosolic transport; GO:0009987 cellular process; GO:0070507 regulation of microtubule cytoskeleton organization; GO:0033043 regulation of organelle organization; GO:0010556 regulation of macromolecule biosynthetic process; GO:0032881 regulation of polysaccharide metabolic process; GO:0006897 endocytosis; GO:0051641 cellular localization; GO:0019882 antigen processing and presentation; GO:0007018 microtubule-based movement; GO:0070727 cellular macromolecule localization; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0051128 regulation of cellular component organization; GO:0022402 cell cycle process; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:1990498 mitotic spindle microtubule; GO:0045334 clathrin-coated endocytic vesicle; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0032588 trans-Golgi network membrane; GO:0036019 endolysosome; GO:0005623 cell; GO:0099080 supramolecular complex; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005765 lysosomal membrane; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0030136 clathrin-coated vesicle; GO:0005622 intracellular; GO:0005764 lysosome; GO:0098589 membrane region; GO:0098791 Golgi subcompartment; GO:0030055 cell-substrate junction; GO:0012510 trans-Golgi network transport vesicle membrane; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0000323 lytic vacuole; GO:0010008 endosome membrane; GO:0099513 polymeric cytoskeletal fiber; GO:0030666 endocytic vesicle membrane; GO:0044430 cytoskeletal part; GO:0036020 endolysosome membrane; GO:0048475 coated membrane; GO:0098797 plasma membrane protein complex; GO:0070161 anchoring junction; GO:0044440 endosomal part; GO:0012506 vesicle membrane; GO:0005576 extracellular region; GO:0030135 coated vesicle; GO:0005798 Golgi-associated vesicle; GO:0005886 plasma membrane; GO:0099081 supramolecular polymer; GO:0031012 extracellular matrix; GO:0030125 clathrin vesicle coat; GO:0043231 intracellular membrane-bounded organelle; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0030118 clathrin coat; GO:0030117 membrane coat; GO:0005905 clathrin-coated pit; GO:0043234 protein complex; GO:0030133 transport vesicle; GO:0043230 extracellular organelle; GO:0030658 transport vesicle membrane; GO:0005874 microtubule; GO:0030130 clathrin coat of trans-Golgi network vesicle; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0098796 membrane protein complex; GO:0030660 Golgi-associated vesicle membrane; GO:0031982 vesicle; GO:0030669 clathrin-coated endocytic vesicle membrane; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0030120 vesicle coat; GO:0030662 coated vesicle membrane; GO:0048770 pigment granule; GO:0072686 mitotic spindle; GO:0005856 cytoskeleton; GO:0030140 trans-Golgi network transport vesicle; GO:0015630 microtubule cytoskeleton; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0005768 endosome; GO:0030132 clathrin coat of coated pit; GO:0030139 endocytic vesicle; GO:0071439 clathrin complex; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0042470 melanosome; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005819 spindle; GO:0030665 clathrin-coated vesicle membrane; GO:0098852 lytic vacuole membrane; GO:0005876 spindle microtubule; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0005802 trans-Golgi network; GO:0005774 vacuolar membrane; GO:0005794 Golgi apparatus; GO:0031984 organelle subcompartment; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0030276 clathrin binding; GO:0003725 double-stranded RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0019901 protein kinase binding; GO:0005515 protein binding; GO:0019900 kinase binding; GO:0005198 structural molecule activity; GO:0019899 enzyme binding; GO:0032051 clathrin light chain binding; ","K04646","CLTC; clathrin heavy chain","hsa04142 Lysosome - Homo sapiens (human); hsa05100 Bacterial invasion of epithelial cells - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04144 Endocytosis - Homo sapiens (human); hsa04961 Endocrine and other factor-regulated calcium reabsorption - Homo sapiens (human); hsa04721 Synaptic vesicle cycle - Homo sapiens (human); ","IPR016025; IPR015348; IPR011990; IPR016024; IPR001473; ","\"Clathrin, heavy chain, linker/propeller domain; Clathrin, heavy chain, linker, core motif; Tetratricopeptide-like helical domain; Armadillo-type fold; Clathrin, heavy chain, propeller, N-terminal; \"\r"]
["Q00796","Sorbitol dehydrogenase OS=Homo sapiens OX=9606 GN=SORD","SORD",38.324,65.014,34.5,11,19,11,1.034,1.005,1.005,1.033,0.985,0.977,0.984,0.453,"cytoplasm\r","GO:0019640 glucuronate catabolic process to xylulose 5-phosphate; GO:0046365 monosaccharide catabolic process; GO:0019319 hexose biosynthetic process; GO:0051674 localization of cell; GO:0006066 alcohol metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0019519 pentitol metabolic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0006062 sorbitol catabolic process; GO:0006006 glucose metabolic process; GO:0009605 response to external stimulus; GO:0051167 xylulose 5-phosphate metabolic process; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0044262 cellular carbohydrate metabolic process; GO:0009719 response to endogenous stimulus; GO:0046686 response to cadmium ion; GO:0032787 monocarboxylic acid metabolic process; GO:0010035 response to inorganic substance; GO:0006970 response to osmotic stress; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0019527 pentitol catabolic process; GO:0044763 single-organism cellular process; GO:0006059 hexitol metabolic process; GO:0072329 monocarboxylic acid catabolic process; GO:0048870 cell motility; GO:0005975 carbohydrate metabolic process; GO:0010038 response to metal ion; GO:0016052 carbohydrate catabolic process; GO:0019405 alditol catabolic process; GO:0090407 organophosphate biosynthetic process; GO:0046395 carboxylic acid catabolic process; GO:1901575 organic substance catabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0006000 fructose metabolic process; GO:0042221 response to chemical; GO:0046688 response to copper ion; GO:0044710 single-organism metabolic process; GO:0040011 locomotion; GO:0006064 glucuronate catabolic process; GO:0006082 organic acid metabolic process; GO:0046370 fructose biosynthetic process; GO:0043436 oxoacid metabolic process; GO:0006060 sorbitol metabolic process; GO:0016051 carbohydrate biosynthetic process; GO:1901615 organic hydroxy compound metabolic process; GO:0009628 response to abiotic stimulus; GO:0044275 cellular carbohydrate catabolic process; GO:0046364 monosaccharide biosynthetic process; GO:0046164 alcohol catabolic process; GO:0050896 response to stimulus; GO:0006063 uronic acid metabolic process; GO:0071704 organic substance metabolic process; GO:0009991 response to extracellular stimulus; GO:0042493 response to drug; GO:0030317 flagellated sperm motility; GO:1901616 organic hydroxy compound catabolic process; GO:0051164 L-xylitol metabolic process; GO:0005996 monosaccharide metabolic process; GO:0044248 cellular catabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0019407 hexitol catabolic process; GO:0009987 cellular process; GO:0019400 alditol metabolic process; GO:0044724 single-organism carbohydrate catabolic process; GO:0006950 response to stress; GO:0044711 single-organism biosynthetic process; GO:0097722 sperm motility; GO:0044712 single-organism catabolic process; GO:0044282 small molecule catabolic process; GO:1901159 xylulose 5-phosphate biosynthetic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0019751 polyol metabolic process; GO:0006793 phosphorus metabolic process; GO:0051160 L-xylitol catabolic process; GO:0019585 glucuronate metabolic process; GO:0044283 small molecule biosynthetic process; GO:0019752 carboxylic acid metabolic process; GO:0016054 organic acid catabolic process; GO:0006928 movement of cell or subcellular component; GO:0019637 organophosphate metabolic process; GO:0031667 response to nutrient levels; GO:0009725 response to hormone; GO:0051179 localization; GO:0009056 catabolic process; GO:0046174 polyol catabolic process; GO:0019318 hexose metabolic process; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0070062 extracellular exosome; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005929 cilium; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0044429 mitochondrial part; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005829 cytosol; GO:0031514 motile cilium; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031975 envelope; GO:0043230 extracellular organelle; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0043167 ion binding; GO:0003939 L-iditol 2-dehydrogenase activity; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0008270 zinc ion binding; GO:0048037 cofactor binding; GO:0016491 oxidoreductase activity; GO:0097159 organic cyclic compound binding; GO:0016614 oxidoreductase activity, acting on CH-OH group of donors; GO:1901363 heterocyclic compound binding; GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; GO:0031320 hexitol dehydrogenase activity; GO:0042802 identical protein binding; GO:0046914 transition metal ion binding; GO:0051287 NAD binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0030246 carbohydrate binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0046526 D-xylulose reductase activity; GO:0036094 small molecule binding; GO:0050662 coenzyme binding; ","K00008","SORD; L-iditol 2-dehydrogenase [EC:1.1.1.14]","hsa00051 Fructose and mannose metabolism - Homo sapiens (human); hsa00040 Pentose and glucuronate interconversions - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR011032; IPR020843; IPR016040; IPR013154; IPR013149; ","\"GroES-like; Polyketide synthase, enoylreductase domain; NAD(P)-binding domain; Alcohol dehydrogenase, N-terminal; Alcohol dehydrogenase, C-terminal; \"\r"]
["Q00839","Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU","HNRNPU",90.583,184.69,32.6,27,54,27,0.942,0.909,0.903,1.096,1.096,1.053,1.178,0.000937,"nucleus\r","GO:0001649 osteoblast differentiation; GO:0065008 regulation of biological quality; GO:0010608 posttranscriptional regulation of gene expression; GO:0043489 RNA stabilization; GO:0051129 negative regulation of cellular component organization; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0032204 regulation of telomere maintenance; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:2000279 negative regulation of DNA biosynthetic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0043170 macromolecule metabolic process; GO:0006396 RNA processing; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0001503 ossification; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0032501 multicellular organismal process; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:0007623 circadian rhythm; GO:0010639 negative regulation of organelle organization; GO:0050789 regulation of biological process; GO:0051052 regulation of DNA metabolic process; GO:0090304 nucleic acid metabolic process; GO:0051053 negative regulation of DNA metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0016071 mRNA metabolic process; GO:0048255 mRNA stabilization; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0032210 regulation of telomere maintenance via telomerase; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0032844 regulation of homeostatic process; GO:0032211 negative regulation of telomere maintenance via telomerase; GO:0043487 regulation of RNA stability; GO:0071704 organic substance metabolic process; GO:1904356 regulation of telomere maintenance via telomere lengthening; GO:0000398 mRNA splicing, via spliceosome; GO:0030154 cell differentiation; GO:1904357 negative regulation of telomere maintenance via telomere lengthening; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0070934 CRD-mediated mRNA stabilization; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0033043 regulation of organelle organization; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0032845 negative regulation of homeostatic process; GO:0044238 primary metabolic process; GO:0043488 regulation of mRNA stability; GO:0032922 circadian regulation of gene expression; GO:2000278 regulation of DNA biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0033044 regulation of chromosome organization; GO:0032205 negative regulation of telomere maintenance; GO:0009890 negative regulation of biosynthetic process; GO:2001251 negative regulation of chromosome organization; GO:0044767 single-organism developmental process; GO:0048511 rhythmic process; GO:0010467 gene expression; GO:0051128 regulation of cellular component organization; GO:0031327 negative regulation of cellular biosynthetic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0070937 CRD-mediated mRNA stability complex; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005681 spliceosomal complex; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031012 extracellular matrix; GO:0005634 nucleus; GO:0035770 ribonucleoprotein granule; GO:0071013 catalytic step 2 spliceosome; GO:0009986 cell surface; GO:1990904 ribonucleoprotein complex; GO:0043234 protein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0003677 DNA binding; GO:0003723 RNA binding; GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0001047 core promoter binding; GO:0070034 telomerase RNA binding; GO:0000975 regulatory region DNA binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0001067 regulatory region nucleic acid binding; GO:0097367 carbohydrate derivative binding; GO:0032553 ribonucleotide binding; GO:0044212 transcription regulatory region DNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0032550 purine ribonucleoside binding; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K12888","HNRNPU; heterogeneous nuclear ribonucleoprotein U","hsa03040 Spliceosome - Homo sapiens (human); ","IPR003034; IPR001870; IPR027417; IPR013320; IPR003877; ","SAP domain; B30.2/SPRY domain; P-loop containing nucleoside triphosphate hydrolase; Concanavalin A-like lectin/glucanase domain; SPRY domain; \r"]
["Q01130","Serine/arginine-rich splicing factor 2 OS=Homo sapiens OX=9606 GN=SRSF2","SRSF2",25.476,53.475,24.9,5,8,5,0.899,0.921,0.977,1.065,1.07,1.07,1.146,0.0312,"nucleus\r","GO:0050658 RNA transport; GO:0097659 nucleic acid-templated transcription; GO:0009058 biosynthetic process; GO:0051168 nuclear export; GO:0051169 nuclear transport; GO:0051253 negative regulation of RNA metabolic process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006353 DNA-templated transcription, termination; GO:2001141 regulation of RNA biosynthetic process; GO:0071427 mRNA-containing ribonucleoprotein complex export from nucleus; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0050657 nucleic acid transport; GO:0015931 nucleobase-containing compound transport; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0043170 macromolecule metabolic process; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0006396 RNA processing; GO:0018130 heterocycle biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0006611 protein export from nucleus; GO:0071166 ribonucleoprotein complex localization; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:0006810 transport; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:1902679 negative regulation of RNA biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006913 nucleocytoplasmic transport; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0050794 regulation of cellular process; GO:0031123 RNA 3'-end processing; GO:0046907 intracellular transport; GO:0006725 cellular aromatic compound metabolic process; GO:0031124 mRNA 3'-end processing; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0051028 mRNA transport; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0048523 negative regulation of cellular process; GO:0051236 establishment of RNA localization; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0006886 intracellular protein transport; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034613 cellular protein localization; GO:0009059 macromolecule biosynthetic process; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0006406 mRNA export from nucleus; GO:0006369 termination of RNA polymerase II transcription; GO:0006403 RNA localization; GO:0006405 RNA export from nucleus; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0071702 organic substance transport; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0051252 regulation of RNA metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0009890 negative regulation of biosynthetic process; GO:0070727 cellular macromolecule localization; GO:0034645 cellular macromolecule biosynthetic process; GO:0071426 ribonucleoprotein complex export from nucleus; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006366 transcription from RNA polymerase II promoter; GO:0010467 gene expression; GO:0031327 negative regulation of cellular biosynthetic process; GO:0051179 localization; GO:0071705 nitrogen compound transport; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043230 extracellular organelle; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0003714 transcription corepressor activity; GO:1901265 nucleoside phosphate binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0003712 transcription cofactor activity; GO:0000988 transcription factor activity, protein binding; GO:0036094 small molecule binding; ","K12891","SFRS2; splicing factor, arginine/serine-rich 2","hsa03040 Spliceosome - Homo sapiens (human); hsa05168 Herpes simplex infection - Homo sapiens (human); ","IPR000504; IPR012677; IPR003954; ","\"RNA recognition motif domain; Nucleotide-binding alpha-beta plait domain; RNA recognition motif domain, eukaryote; \"\r"]
["Q01415","N-acetylgalactosamine kinase OS=Homo sapiens OX=9606 GN=GALK2","GALK2",50.378,4.7489,5,2,3,2,0.892,0.848,0.857,1.066,1.123,1.202,1.306,0.0022,"cytoplasm\r","GO:0016310 phosphorylation; GO:0044281 small molecule metabolic process; GO:0044699 single-organism process; GO:0044238 primary metabolic process; GO:0005975 carbohydrate metabolic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0008152 metabolic process; GO:0006793 phosphorus metabolic process; GO:0044262 cellular carbohydrate metabolic process; GO:0044710 single-organism metabolic process; GO:0046835 carbohydrate phosphorylation; GO:0005996 monosaccharide metabolic process; GO:0006012 galactose metabolic process; GO:0009987 cellular process; GO:0019318 hexose metabolic process; ","GO:0044424 intracellular part; GO:0005623 cell; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0033858 N-acetylgalactosamine kinase activity; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0019200 carbohydrate kinase activity; GO:0097367 carbohydrate derivative binding; GO:0016301 kinase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0016740 transferase activity; GO:0004335 galactokinase activity; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K18674",null,null,"IPR019539; IPR020568; IPR006204; IPR014721; IPR013750; ","\"Galactokinase galactose-binding domain; Ribosomal protein S5 domain 2-type fold; GHMP kinase N-terminal domain; Ribosomal protein S5 domain 2-type fold, subgroup; GHMP kinase, C-terminal domain; \"\r"]
["Q01469","Fatty acid-binding protein, epidermal OS=Homo sapiens OX=9606 GN=FABP5","FABP5",15.164,215.99,70.4,15,50,15,0.501,0.541,0.549,1.45,1.477,1.479,2.769,1.98e-06,"extracellular\r","GO:0046470 phosphatidylcholine metabolic process; GO:0045321 leukocyte activation; GO:0046486 glycerolipid metabolic process; GO:0008654 phospholipid biosynthetic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0008610 lipid biosynthetic process; GO:0051234 establishment of localization; GO:0009611 response to wounding; GO:0006006 glucose metabolic process; GO:0046461 neutral lipid catabolic process; GO:0008152 metabolic process; GO:0006639 acylglycerol metabolic process; GO:0006650 glycerophospholipid metabolic process; GO:0015758 glucose transport; GO:0008544 epidermis development; GO:0006656 phosphatidylcholine biosynthetic process; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0006629 lipid metabolic process; GO:0032502 developmental process; GO:0002443 leukocyte mediated immunity; GO:0009888 tissue development; GO:0044281 small molecule metabolic process; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0005975 carbohydrate metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0090407 organophosphate biosynthetic process; GO:0006810 transport; GO:0044723 single-organism carbohydrate metabolic process; GO:1901575 organic substance catabolic process; GO:0008645 hexose transport; GO:0032940 secretion by cell; GO:0044710 single-organism metabolic process; GO:0046474 glycerophospholipid biosynthetic process; GO:0043299 leukocyte degranulation; GO:0048856 anatomical structure development; GO:0046503 glycerolipid catabolic process; GO:0002283 neutrophil activation involved in immune response; GO:0015749 monosaccharide transport; GO:0002252 immune effector process; GO:0097164 ammonium ion metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:0046464 acylglycerol catabolic process; GO:0071704 organic substance metabolic process; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0005996 monosaccharide metabolic process; GO:0008643 carbohydrate transport; GO:0044248 cellular catabolic process; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0019433 triglyceride catabolic process; GO:0006638 neutral lipid metabolic process; GO:0016042 lipid catabolic process; GO:0044711 single-organism biosynthetic process; GO:0006950 response to stress; GO:0044712 single-organism catabolic process; GO:0016192 vesicle-mediated transport; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:0043312 neutrophil degranulation; GO:1901576 organic substance biosynthetic process; GO:0002263 cell activation involved in immune response; GO:0044249 cellular biosynthetic process; GO:0045017 glycerolipid biosynthetic process; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0006641 triglyceride metabolic process; GO:0006793 phosphorus metabolic process; GO:0019637 organophosphate metabolic process; GO:0044242 cellular lipid catabolic process; GO:0001775 cell activation; GO:0006644 phospholipid metabolic process; GO:0006955 immune response; GO:0051179 localization; GO:0009056 catabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0006887 exocytosis; GO:0019318 hexose metabolic process; ","GO:0016020 membrane; GO:0034774 secretory granule lumen; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0042582 azurophil granule; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0030667 secretory granule membrane; GO:0060205 cytoplasmic vesicle lumen; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0031406 carboxylic acid binding; GO:0005488 binding; GO:0043167 ion binding; GO:0008289 lipid binding; GO:0043177 organic acid binding; GO:0005515 protein binding; GO:0043168 anion binding; GO:0033293 monocarboxylic acid binding; GO:0005504 fatty acid binding; GO:0005215 transporter activity; GO:0036094 small molecule binding; ","K08754","FABP5; fatty acid-binding protein 5, epidermal","hsa03320 PPAR signaling pathway - Homo sapiens (human); ","IPR000463; IPR012674; IPR000566; IPR011038; ","Cytosolic fatty-acid binding; Calycin; Lipocalin/cytosolic fatty-acid binding domain; Calycin-like; \r"]
["Q01518","Adenylyl cyclase-associated protein 1 OS=Homo sapiens OX=9606 GN=CAP1","CAP1",51.901,156.73,48.4,24,62,23,0.934,1,0.949,1.043,1.054,1.022,1.082,0.0247,"cytoplasm\r","GO:0044700 single organism signaling; GO:0051349 positive regulation of lyase activity; GO:0045321 leukocyte activation; GO:0051674 localization of cell; GO:0048869 cellular developmental process; GO:0009891 positive regulation of biosynthetic process; GO:0032989 cellular component morphogenesis; GO:0044699 single-organism process; GO:0030819 positive regulation of cAMP biosynthetic process; GO:0051234 establishment of localization; GO:0030810 positive regulation of nucleotide biosynthetic process; GO:0007165 signal transduction; GO:0030036 actin cytoskeleton organization; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0044093 positive regulation of molecular function; GO:0030814 regulation of cAMP metabolic process; GO:0010562 positive regulation of phosphorus metabolic process; GO:0030808 regulation of nucleotide biosynthetic process; GO:1900373 positive regulation of purine nucleotide biosynthetic process; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0051174 regulation of phosphorus metabolic process; GO:0002443 leukocyte mediated immunity; GO:0030802 regulation of cyclic nucleotide biosynthetic process; GO:0045937 positive regulation of phosphate metabolic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0030816 positive regulation of cAMP metabolic process; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0008154 actin polymerization or depolymerization; GO:0048870 cell motility; GO:0007163 establishment or maintenance of cell polarity; GO:0031323 regulation of cellular metabolic process; GO:0023052 signaling; GO:0002444 myeloid leukocyte mediated immunity; GO:0051339 regulation of lyase activity; GO:0000902 cell morphogenesis; GO:0006810 transport; GO:0031279 regulation of cyclase activity; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:1900371 regulation of purine nucleotide biosynthetic process; GO:0050790 regulation of catalytic activity; GO:0032940 secretion by cell; GO:0045762 positive regulation of adenylate cyclase activity; GO:0001667 ameboidal-type cell migration; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0045981 positive regulation of nucleotide metabolic process; GO:0040011 locomotion; GO:0043299 leukocyte degranulation; GO:0030804 positive regulation of cyclic nucleotide biosynthetic process; GO:0048856 anatomical structure development; GO:0097435 supramolecular fiber organization; GO:0006140 regulation of nucleotide metabolic process; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0016477 cell migration; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0030801 positive regulation of cyclic nucleotide metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0007015 actin filament organization; GO:1900544 positive regulation of purine nucleotide metabolic process; GO:0050896 response to stimulus; GO:0009653 anatomical structure morphogenesis; GO:0045761 regulation of adenylate cyclase activity; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0009889 regulation of biosynthetic process; GO:0030817 regulation of cAMP biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0006898 receptor-mediated endocytosis; GO:0036230 granulocyte activation; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0006897 endocytosis; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0030799 regulation of cyclic nucleotide metabolic process; GO:0002263 cell activation involved in immune response; GO:0043085 positive regulation of catalytic activity; GO:1900542 regulation of purine nucleotide metabolic process; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0031325 positive regulation of cellular metabolic process; GO:0031281 positive regulation of cyclase activity; GO:0030029 actin filament-based process; GO:0007190 activation of adenylate cyclase activity; GO:0001775 cell activation; GO:0006928 movement of cell or subcellular component; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0006955 immune response; GO:0051179 localization; GO:0071840 cellular component organization or biogenesis; GO:0006887 exocytosis; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005938 cell cortex; GO:0031410 cytoplasmic vesicle; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0099568 cytoplasmic region; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0030863 cortical cytoskeleton; GO:0030864 cortical actin cytoskeleton; GO:0044424 intracellular part; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0031983 vesicle lumen; GO:0005925 focal adhesion; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030055 cell-substrate junction; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0015629 actin cytoskeleton; GO:0005886 plasma membrane; GO:0042582 azurophil granule; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0005766 primary lysosome; GO:0044448 cell cortex part; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0003779 actin binding; GO:0005515 protein binding; GO:0008092 cytoskeletal protein binding; GO:0008179 adenylate cyclase binding; GO:0005488 binding; GO:0019899 enzyme binding; ","K17261",null,null,"IPR006599; IPR013992; IPR016098; IPR017901; IPR013912; ","\"CARP motif; Adenylate cyclase-associated CAP, N-terminal; Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal; C-CAP/cofactor C-like domain; Adenylate cyclase-associated CAP, C-terminal; \"\r"]
["Q01844","RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1","EWSR1",68.477,24.085,4.4,3,6,3,1.058,0.96,1.019,0.981,0.99,1.002,0.979,0.517,"nucleus\r","GO:0050794 regulation of cellular process; GO:0006725 cellular aromatic compound metabolic process; GO:0097659 nucleic acid-templated transcription; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0006355 regulation of transcription, DNA-templated; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0044238 primary metabolic process; GO:0051252 regulation of RNA metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0034645 cellular macromolecule biosynthetic process; GO:0090304 nucleic acid metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006351 transcription, DNA-templated; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0010467 gene expression; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0043232 intracellular non-membrane-bounded organelle; GO:0071944 cell periphery; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005730 nucleolus; GO:0005623 cell; GO:0044422 organelle part; GO:0005886 plasma membrane; GO:0043228 non-membrane-bounded organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031974 membrane-enclosed lumen; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:1901265 nucleoside phosphate binding; GO:0042802 identical protein binding; GO:0046914 transition metal ion binding; GO:0005488 binding; GO:0043167 ion binding; GO:0003676 nucleic acid binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0008270 zinc ion binding; GO:0005516 calmodulin binding; GO:0036094 small molecule binding; ","K13209","EWSR1; RNA-binding protein EWS","hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human); ","IPR000504; IPR012677; IPR001876; ","\"RNA recognition motif domain; Nucleotide-binding alpha-beta plait domain; Zinc finger, RanBP2-type; \"\r"]
["Q01970","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 OS=Homo sapiens OX=9606 GN=PLCB3","PLCB3",138.8,4.1407,2.6,3,3,3,0.958,1.05,0.923,0.98,1.009,1.085,1.049,0.379,"nucleus\r","GO:0008217 regulation of blood pressure; GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:1901615 organic hydroxy compound metabolic process; GO:0007166 cell surface receptor signaling pathway; GO:0006066 alcohol metabolic process; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0035567 non-canonical Wnt signaling pathway; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0008015 blood circulation; GO:0003073 regulation of systemic arterial blood pressure; GO:0099537 trans-synaptic signaling; GO:0098916 anterograde trans-synaptic signaling; GO:0016055 Wnt signaling pathway; GO:0009987 cellular process; GO:0006629 lipid metabolic process; GO:0016042 lipid catabolic process; GO:0051716 cellular response to stimulus; GO:0003008 system process; GO:0035556 intracellular signal transduction; GO:0044712 single-organism catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0007223 Wnt signaling pathway, calcium modulating pathway; GO:0044238 primary metabolic process; GO:0023052 signaling; GO:0019751 polyol metabolic process; GO:0032501 multicellular organismal process; GO:0198738 cell-cell signaling by wnt; GO:1901575 organic substance catabolic process; GO:0050789 regulation of biological process; GO:0099536 synaptic signaling; GO:0007267 cell-cell signaling; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0019637 organophosphate metabolic process; GO:0043647 inositol phosphate metabolic process; GO:0007268 chemical synaptic transmission; GO:0003013 circulatory system process; GO:0009056 catabolic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0004629 phospholipase C activity; GO:0043167 ion binding; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0016298 lipase activity; GO:0005516 calmodulin binding; GO:0004871 signal transducer activity; GO:0050839 cell adhesion molecule binding; GO:0004435 phosphatidylinositol phospholipase C activity; GO:0042578 phosphoric ester hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0045296 cadherin binding; GO:0004620 phospholipase activity; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0008081 phosphoric diester hydrolase activity; GO:0005509 calcium ion binding; ","K05858","PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]","hsa04072 Phospholipase D signaling pathway - Homo sapiens (human); hsa04015 Rap1 signaling pathway - Homo sapiens (human); hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human); hsa04924 Renin secretion - Homo sapiens (human); hsa04911 Insulin secretion - Homo sapiens (human); hsa04970 Salivary secretion - Homo sapiens (human); hsa04724 Glutamatergic synapse - Homo sapiens (human); hsa00562 Inositol phosphate metabolism - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa04934 Cushing's syndrome - Homo sapiens (human); hsa04071 Sphingolipid signaling pathway - Homo sapiens (human); hsa04070 Phosphatidylinositol signaling system - Homo sapiens (human); hsa04933 AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human); hsa04922 Glucagon signaling pathway - Homo sapiens (human); hsa04611 Platelet activation - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04927 Cortisol synthesis and secretion - Homo sapiens (human); hsa04971 Gastric acid secretion - Homo sapiens (human); hsa04915 Estrogen signaling pathway - Homo sapiens (human); hsa05143 African trypanosomiasis - Homo sapiens (human); hsa04725 Cholinergic synapse - Homo sapiens (human); hsa04310 Wnt signaling pathway - Homo sapiens (human); hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04921 Oxytocin signaling pathway - Homo sapiens (human); hsa05142 Chagas disease (American trypanosomiasis) - Homo sapiens (human); hsa04728 Dopaminergic synapse - Homo sapiens (human); hsa04371 Apelin signaling pathway - Homo sapiens (human); hsa04973 Carbohydrate digestion and absorption - Homo sapiens (human); hsa04916 Melanogenesis - Homo sapiens (human); hsa04020 Calcium signaling pathway - Homo sapiens (human); hsa04270 Vascular smooth muscle contraction - Homo sapiens (human); hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human); hsa04726 Serotonergic synapse - Homo sapiens (human); hsa04750 Inflammatory mediator regulation of TRP channels - Homo sapiens (human); hsa04062 Chemokine signaling pathway - Homo sapiens (human); hsa04925 Aldosterone synthesis and secretion - Homo sapiens (human); hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human); hsa04540 Gap junction - Homo sapiens (human); hsa04912 GnRH signaling pathway - Homo sapiens (human); hsa04972 Pancreatic secretion - Homo sapiens (human); hsa05146 Amoebiasis - Homo sapiens (human); hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human); hsa04730 Long-term depression - Homo sapiens (human); hsa04918 Thyroid hormone synthesis - Homo sapiens (human); hsa04742 Taste transduction - Homo sapiens (human); hsa04720 Long-term potentiation - Homo sapiens (human); hsa04961 Endocrine and other factor-regulated calcium reabsorption - Homo sapiens (human); hsa04713 Circadian entrainment - Homo sapiens (human); hsa04926 Relaxin signaling pathway - Homo sapiens (human); hsa04928 Parathyroid hormone synthesis, secretion and action - Homo sapiens (human); ","IPR015359; IPR000909; IPR011992; IPR001711; IPR017946; IPR011993; IPR000008; IPR014815; ","\"Phosphoinositide-specific phospholipase C, EF-hand-like domain; Phosphatidylinositol-specific phospholipase C, X domain; EF-hand domain pair; Phospholipase C, phosphatidylinositol-specific, Y domain; PLC-like phosphodiesterase, TIM beta/alpha-barrel domain; PH domain-like; C2 domain; Phospholipase C-beta, C-terminal domain; \"\r"]
["Q02161","Blood group Rh(D) polypeptide OS=Homo sapiens OX=9606 GN=RHD","RHD",45.21,3.0456,2.2,1,2,1,0.771,0.778,0.762,1.206,1.232,1.23,1.587,4.55e-07,"plasma membrane\r","GO:0015695 organic cation transport; GO:0006810 transport; GO:0055085 transmembrane transport; GO:0098655 cation transmembrane transport; GO:0034220 ion transmembrane transport; GO:0015696 ammonium transport; GO:0006812 cation transport; GO:0006811 ion transport; GO:0072488 ammonium transmembrane transport; GO:0071702 organic substance transport; GO:0051179 localization; GO:0071705 nitrogen compound transport; GO:0051234 establishment of localization; ","GO:0016020 membrane; GO:0031226 intrinsic component of plasma membrane; GO:0044459 plasma membrane part; GO:0044425 membrane part; GO:0044464 cell part; GO:0071944 cell periphery; GO:0031224 intrinsic component of membrane; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; ","GO:0008519 ammonium transmembrane transporter activity; GO:0015075 ion transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0008324 cation transmembrane transporter activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0022857 transmembrane transporter activity; GO:0005215 transporter activity; ","K06579",null,null,"IPR024041; IPR029020; ","Ammonium transporter AmtB-like domain; Ammonium/urea transporter; \r"]
["Q02218","2-oxoglutarate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=OGDH","OGDH",115.93,309.37,34.2,33,50,33,1.002,1.018,1.066,0.976,0.979,0.93,0.935,0.0541,"mitochondria\r","GO:0009116 nucleoside metabolic process; GO:0006165 nucleoside diphosphate phosphorylation; GO:0019362 pyridine nucleotide metabolic process; GO:0021766 hippocampus development; GO:0006096 glycolytic process; GO:0021772 olfactory bulb development; GO:0007420 brain development; GO:0009185 ribonucleoside diphosphate metabolic process; GO:0044237 cellular metabolic process; GO:0021537 telencephalon development; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0021885 forebrain cell migration; GO:0032787 monocarboxylic acid metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0046487 glyoxylate metabolic process; GO:0006790 sulfur compound metabolic process; GO:0007399 nervous system development; GO:0072350 tricarboxylic acid metabolic process; GO:0009179 purine ribonucleoside diphosphate metabolic process; GO:0048699 generation of neurons; GO:0021988 olfactory lobe development; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006081 cellular aldehyde metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0006732 coenzyme metabolic process; GO:0048870 cell motility; GO:0005975 carbohydrate metabolic process; GO:0032501 multicellular organismal process; GO:0021549 cerebellum development; GO:0046395 carboxylic acid catabolic process; GO:1901575 organic substance catabolic process; GO:0022029 telencephalon cell migration; GO:0048513 animal organ development; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0019674 NAD metabolic process; GO:0044710 single-organism metabolic process; GO:0007417 central nervous system development; GO:0061034 olfactory bulb mitral cell layer development; GO:0009063 cellular amino acid catabolic process; GO:0021695 cerebellar cortex development; GO:0009126 purine nucleoside monophosphate metabolic process; GO:0043436 oxoacid metabolic process; GO:0016310 phosphorylation; GO:0044707 single-multicellular organism process; GO:0046496 nicotinamide nucleotide metabolic process; GO:0009259 ribonucleotide metabolic process; GO:0009066 aspartate family amino acid metabolic process; GO:0021794 thalamus development; GO:0021953 central nervous system neuron differentiation; GO:0021879 forebrain neuron differentiation; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0044248 cellular catabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0030900 forebrain development; GO:0007275 multicellular organism development; GO:0009119 ribonucleoside metabolic process; GO:0030902 hindbrain development; GO:0006104 succinyl-CoA metabolic process; GO:0021859 pyramidal neuron differentiation; GO:0048731 system development; GO:0006553 lysine metabolic process; GO:0006099 tricarboxylic acid cycle; GO:0035383 thioester metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:1901605 alpha-amino acid metabolic process; GO:0044238 primary metabolic process; GO:0006163 purine nucleotide metabolic process; GO:0030182 neuron differentiation; GO:0021954 central nervous system neuron development; GO:0006793 phosphorus metabolic process; GO:0016054 organic acid catabolic process; GO:0006928 movement of cell or subcellular component; GO:0021872 forebrain generation of neurons; GO:0019637 organophosphate metabolic process; GO:0051179 localization; GO:0021544 subpallium development; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0006757 ATP generation from ADP; GO:1901606 alpha-amino acid catabolic process; GO:0042278 purine nucleoside metabolic process; GO:0046031 ADP metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0051674 localization of cell; GO:0009117 nucleotide metabolic process; GO:0048869 cellular developmental process; GO:0048666 neuron development; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0046939 nucleotide phosphorylation; GO:0021761 limbic system development; GO:0009135 purine nucleoside diphosphate metabolic process; GO:0072524 pyridine-containing compound metabolic process; GO:0021884 forebrain neuron development; GO:0006796 phosphate-containing compound metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0022028 tangential migration from the subventricular zone to the olfactory bulb; GO:0060322 head development; GO:0006103 2-oxoglutarate metabolic process; GO:0032502 developmental process; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0055114 oxidation-reduction process; GO:1901360 organic cyclic compound metabolic process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0051186 cofactor metabolic process; GO:0016052 carbohydrate catabolic process; GO:0006101 citrate metabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0009068 aspartate family amino acid catabolic process; GO:0021860 pyramidal neuron development; GO:0021536 diencephalon development; GO:0015980 energy derivation by oxidation of organic compounds; GO:0022037 metencephalon development; GO:0006554 lysine catabolic process; GO:0040011 locomotion; GO:1901657 glycosyl compound metabolic process; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:0021543 pallium development; GO:0043648 dicarboxylic acid metabolic process; GO:0016477 cell migration; GO:0006725 cellular aromatic compound metabolic process; GO:0006734 NADH metabolic process; GO:0048468 cell development; GO:0071704 organic substance metabolic process; GO:0006090 pyruvate metabolic process; GO:0030154 cell differentiation; GO:0034641 cellular nitrogen compound metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0009987 cellular process; GO:0009132 nucleoside diphosphate metabolic process; GO:0046034 ATP metabolic process; GO:0044724 single-organism carbohydrate catabolic process; GO:0044712 single-organism catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044282 small molecule catabolic process; GO:0045333 cellular respiration; GO:0006637 acyl-CoA metabolic process; GO:0046128 purine ribonucleoside metabolic process; GO:1901565 organonitrogen compound catabolic process; GO:0044767 single-organism developmental process; GO:0009060 aerobic respiration; GO:0019752 carboxylic acid metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0021756 striatum development; GO:0009056 catabolic process; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0045240 dihydrolipoyl dehydrogenase complex; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005759 mitochondrial matrix; GO:0044429 mitochondrial part; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:1990234 transferase complex; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:1990204 oxidoreductase complex; GO:0031975 envelope; GO:0045252 oxoglutarate dehydrogenase complex; GO:0043234 protein complex; GO:0045239 tricarboxylic acid cycle enzyme complex; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0019842 vitamin binding; GO:0031072 heat shock protein binding; GO:0051087 chaperone binding; GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors; GO:0043167 ion binding; GO:0005515 protein binding; GO:0048037 cofactor binding; GO:1901681 sulfur compound binding; GO:0030976 thiamine pyrophosphate binding; GO:0016491 oxidoreductase activity; GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0034602 oxoglutarate dehydrogenase (NAD+) activity; GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity; GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor; GO:0036094 small molecule binding; GO:0050662 coenzyme binding; ","K00164","OGDH; 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]","hsa00310 Lysine degradation - Homo sapiens (human); hsa00380 Tryptophan metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00020 Citrate cycle (TCA cycle) - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); ","IPR001017; IPR032106; IPR031717; IPR029061; IPR005475; ","\"Dehydrogenase, E1 component; 2-oxoglutarate dehydrogenase E1 component, N-terminal domain; Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal; Thiamin diphosphate-binding fold; Transketolase-like, pyrimidine-binding domain; \"\r"]
["Q02487","Desmocollin-2 OS=Homo sapiens OX=9606 GN=DSC2","DSC2",99.961,23.165,6.8,5,6,4,0.942,0.889,0.83,1.14,1.158,1.118,1.284,0.00272,"endoplasmic reticulum\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0086069 bundle of His cell to Purkinje myocyte communication; GO:0031424 keratinization; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0034113 heterotypic cell-cell adhesion; GO:0098901 regulation of cardiac muscle cell action potential; GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication; GO:0061337 cardiac conduction; GO:0022610 biological adhesion; GO:0009913 epidermal cell differentiation; GO:0009605 response to external stimulus; GO:0016337 single organismal cell-cell adhesion; GO:0098900 regulation of action potential; GO:0007154 cell communication; GO:0055117 regulation of cardiac muscle contraction; GO:0032879 regulation of localization; GO:1903115 regulation of actin filament-based movement; GO:0007155 cell adhesion; GO:0008544 epidermis development; GO:0044057 regulation of system process; GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0051716 cellular response to stimulus; GO:0043588 skin development; GO:0098911 regulation of ventricular cardiac muscle cell action potential; GO:0030216 keratinocyte differentiation; GO:0009888 tissue development; GO:0070268 cornification; GO:0035637 multicellular organismal signaling; GO:0098609 cell-cell adhesion; GO:0044763 single-organism cellular process; GO:0090257 regulation of muscle system process; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0006942 regulation of striated muscle contraction; GO:0042391 regulation of membrane potential; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0098602 single organism cell adhesion; GO:0048856 anatomical structure development; GO:0030855 epithelial cell differentiation; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0044707 single-multicellular organism process; GO:0009267 cellular response to starvation; GO:1903522 regulation of blood circulation; GO:0086042 cardiac muscle cell-cardiac muscle cell adhesion; GO:0008016 regulation of heart contraction; GO:0050896 response to stimulus; GO:0034109 homotypic cell-cell adhesion; GO:0086004 regulation of cardiac muscle cell contraction; GO:0051239 regulation of multicellular organismal process; GO:0031669 cellular response to nutrient levels; GO:0009991 response to extracellular stimulus; GO:0030154 cell differentiation; GO:0086091 regulation of heart rate by cardiac conduction; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0006950 response to stress; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0006937 regulation of muscle contraction; GO:0071496 cellular response to external stimulus; GO:0032970 regulation of actin filament-based process; GO:0031668 cellular response to extracellular stimulus; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0002027 regulation of heart rate; GO:0042594 response to starvation; GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules; GO:0031667 response to nutrient levels; GO:0012501 programmed cell death; GO:0086065 cell communication involved in cardiac conduction; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0044291 cell-cell contact zone; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005913 cell-cell adherens junction; GO:0005911 cell-cell junction; GO:0005623 cell; GO:0014704 intercalated disc; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0005912 adherens junction; GO:0043227 membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0070161 anchoring junction; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0030057 desmosome; GO:0043226 organelle; GO:0001533 cornified envelope; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0086080 protein binding involved in heterotypic cell-cell adhesion; GO:0098631 protein binding involved in cell adhesion; GO:0005488 binding; GO:0043167 ion binding; GO:0046872 metal ion binding; GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication; GO:0043169 cation binding; GO:0005515 protein binding; GO:0005509 calcium ion binding; GO:0098632 protein binding involved in cell-cell adhesion; ","K07601","DSC2; desmocollin 2","hsa05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human); ","IPR015919; IPR027397; IPR000233; IPR014868; IPR002126; ","\"Cadherin-like; Catenin binding domain; Cadherin, cytoplasmic domain; Cadherin prodomain; Cadherin; \"\r"]
["Q02750","Dual specificity mitogen-activated protein kinase kinase 1 OS=Homo sapiens OX=9606 GN=MAP2K1","MAP2K1",43.439,29.466,22.4,8,8,6,1.089,0.881,1.001,1.063,1,0.974,1.022,0.727,"cytoplasm\r","GO:0044700 single organism signaling; GO:0032872 regulation of stress-activated MAPK cascade; GO:0048732 gland development; GO:0022414 reproductive process; GO:0043009 chordate embryonic development; GO:0030323 respiratory tube development; GO:0010608 posttranscriptional regulation of gene expression; GO:0001892 embryonic placenta development; GO:0009891 positive regulation of biosynthetic process; GO:0030878 thyroid gland development; GO:0018212 peptidyl-tyrosine modification; GO:0044237 cellular metabolic process; GO:0060674 placenta blood vessel development; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0009913 epidermal cell differentiation; GO:1903798 regulation of production of miRNAs involved in gene silencing by miRNA; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0044093 positive regulation of molecular function; GO:0008544 epidermis development; GO:0009790 embryo development; GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA; GO:0070570 regulation of neuron projection regeneration; GO:0021587 cerebellum morphogenesis; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0043588 skin development; GO:0021575 hindbrain morphogenesis; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0060148 positive regulation of posttranscriptional gene silencing; GO:0044763 single-organism cellular process; GO:0002520 immune system development; GO:0048870 cell motility; GO:0006935 chemotaxis; GO:0051704 multi-organism process; GO:0050673 epithelial cell proliferation; GO:0000165 MAPK cascade; GO:0042063 gliogenesis; GO:0080135 regulation of cellular response to stress; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010975 regulation of neuron projection development; GO:0030855 epithelial cell differentiation; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0000003 reproduction; GO:0072359 circulatory system development; GO:0016310 phosphorylation; GO:0044707 single-multicellular organism process; GO:0048519 negative regulation of biological process; GO:0009653 anatomical structure morphogenesis; GO:0060428 lung epithelium development; GO:0050772 positive regulation of axonogenesis; GO:0060541 respiratory system development; GO:0009889 regulation of biosynthetic process; GO:2000641 regulation of early endosome to late endosome transport; GO:1902680 positive regulation of RNA biosynthetic process; GO:0061458 reproductive system development; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0030902 hindbrain development; GO:0023014 signal transduction by protein phosphorylation; GO:0006950 response to stress; GO:0060440 trachea formation; GO:0051960 regulation of nervous system development; GO:0060284 regulation of cell development; GO:0002376 immune system process; GO:0032101 regulation of response to external stimulus; GO:0008283 cell proliferation; GO:0060966 regulation of gene silencing by RNA; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0034248 regulation of cellular amide metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:0043412 macromolecule modification; GO:1903034 regulation of response to wounding; GO:0051674 localization of cell; GO:0001568 blood vessel development; GO:0070920 regulation of production of small RNA involved in gene silencing by RNA; GO:0023051 regulation of signaling; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0006796 phosphate-containing compound metabolic process; GO:0090170 regulation of Golgi inheritance; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0035897 proteolysis in other organism; GO:0033674 positive regulation of kinase activity; GO:0051726 regulation of cell cycle; GO:0045937 positive regulation of phosphate metabolic process; GO:0060147 regulation of posttranscriptional gene silencing; GO:0031326 regulation of cellular biosynthetic process; GO:1903649 regulation of cytoplasmic transport; GO:0048608 reproductive structure development; GO:0001944 vasculature development; GO:0048645 animal organ formation; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0045664 regulation of neuron differentiation; GO:0035270 endocrine system development; GO:0065009 regulation of molecular function; GO:0036211 protein modification process; GO:0043549 regulation of kinase activity; GO:0060425 lung morphogenesis; GO:1903358 regulation of Golgi organization; GO:0045786 negative regulation of cell cycle; GO:0060502 epithelial cell proliferation involved in lung morphogenesis; GO:0070371 ERK1 and ERK2 cascade; GO:0060255 regulation of macromolecule metabolic process; GO:0010770 positive regulation of cell morphogenesis involved in differentiation; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0006468 protein phosphorylation; GO:0060438 trachea development; GO:0043408 regulation of MAPK cascade; GO:0023056 positive regulation of signaling; GO:0010647 positive regulation of cell communication; GO:0045595 regulation of cell differentiation; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0035556 intracellular signal transduction; GO:0007050 cell cycle arrest; GO:0051049 regulation of transport; GO:0009792 embryo development ending in birth or egg hatching; GO:0001932 regulation of protein phosphorylation; GO:0033043 regulation of organelle organization; GO:0001934 positive regulation of protein phosphorylation; GO:0043085 positive regulation of catalytic activity; GO:0018193 peptidyl-amino acid modification; GO:0010001 glial cell differentiation; GO:0000187 activation of MAPK activity; GO:0022402 cell cycle process; GO:0007049 cell cycle; GO:0050767 regulation of neurogenesis; GO:0060627 regulation of vesicle-mediated transport; GO:0032270 positive regulation of cellular protein metabolic process; GO:0007420 brain development; GO:0060020 Bergmann glial cell differentiation; GO:0008285 negative regulation of cell proliferation; GO:0009605 response to external stimulus; GO:0007507 heart development; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0044702 single organism reproductive process; GO:0010562 positive regulation of phosphorus metabolic process; GO:0042327 positive regulation of phosphorylation; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0051347 positive regulation of transferase activity; GO:0007399 nervous system development; GO:0051174 regulation of phosphorus metabolic process; GO:0003006 developmental process involved in reproduction; GO:0031346 positive regulation of cell projection organization; GO:0045893 positive regulation of transcription, DNA-templated; GO:0090398 cellular senescence; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0021549 cerebellum development; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0007569 cell aging; GO:0001701 in utero embryonic development; GO:0007417 central nervous system development; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0021696 cerebellar cortex morphogenesis; GO:0010604 positive regulation of macromolecule metabolic process; GO:0009887 animal organ morphogenesis; GO:0042330 taxis; GO:0006464 cellular protein modification process; GO:0021695 cerebellar cortex development; GO:0051094 positive regulation of developmental process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0042127 regulation of cell proliferation; GO:0001890 placenta development; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:0071902 positive regulation of protein serine/threonine kinase activity; GO:0045597 positive regulation of cell differentiation; GO:0051239 regulation of multicellular organismal process; GO:0060341 regulation of cellular localization; GO:0070372 regulation of ERK1 and ERK2 cascade; GO:0060964 regulation of gene silencing by miRNA; GO:0032147 activation of protein kinase activity; GO:0010628 positive regulation of gene expression; GO:0051338 regulation of transferase activity; GO:0060968 regulation of gene silencing; GO:0051171 regulation of nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0048679 regulation of axon regeneration; GO:0009966 regulation of signal transduction; GO:0051254 positive regulation of RNA metabolic process; GO:1902531 regulation of intracellular signal transduction; GO:0060439 trachea morphogenesis; GO:0048731 system development; GO:0072358 cardiovascular system development; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0050770 regulation of axonogenesis; GO:0030182 neuron differentiation; GO:0043406 positive regulation of MAP kinase activity; GO:0051247 positive regulation of protein metabolic process; GO:0048538 thymus development; GO:0006793 phosphorus metabolic process; GO:0010976 positive regulation of neuron projection development; GO:0006928 movement of cell or subcellular component; GO:0050769 positive regulation of neurogenesis; GO:0048584 positive regulation of response to stimulus; GO:0031328 positive regulation of cellular biosynthetic process; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0045666 positive regulation of neuron differentiation; GO:1902533 positive regulation of intracellular signal transduction; GO:0022008 neurogenesis; GO:0051130 positive regulation of cellular component organization; GO:0021697 cerebellar cortex formation; GO:0070302 regulation of stress-activated protein kinase signaling cascade; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0060322 head development; GO:0010720 positive regulation of cell development; GO:0032502 developmental process; GO:0030324 lung development; GO:0060429 epithelium development; GO:0010468 regulation of gene expression; GO:0035295 tube development; GO:0009888 tissue development; GO:0030216 keratinocyte differentiation; GO:0051962 positive regulation of nervous system development; GO:0048522 positive regulation of cellular process; GO:0032386 regulation of intracellular transport; GO:0018108 peptidyl-tyrosine phosphorylation; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0007568 aging; GO:0048708 astrocyte differentiation; GO:0019222 regulation of metabolic process; GO:0022037 metencephalon development; GO:0019220 regulation of phosphate metabolic process; GO:0040011 locomotion; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0045859 regulation of protein kinase activity; GO:0060324 face development; GO:0043405 regulation of MAP kinase activity; GO:0048568 embryonic organ development; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0060711 labyrinthine layer development; GO:0031344 regulation of cell projection organization; GO:0050896 response to stimulus; GO:0006508 proteolysis; GO:0009987 cellular process; GO:0031401 positive regulation of protein modification process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045860 positive regulation of protein kinase activity; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0048534 hematopoietic or lymphoid organ development; GO:0006417 regulation of translation; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0009967 positive regulation of signal transduction; GO:0051128 regulation of cellular component organization; GO:0043410 positive regulation of MAPK cascade; GO:0070374 positive regulation of ERK1 and ERK2 cascade; GO:2000637 positive regulation of gene silencing by miRNA; GO:0022604 regulation of cell morphogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0005815 microtubule organizing center; GO:0005925 focal adhesion; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0005770 late endosome; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0004728 signal transducer, downstream of receptor, with protein tyrosine phosphatase activity; GO:0047485 protein N-terminus binding; GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0016791 phosphatase activity; GO:0004713 protein tyrosine kinase activity; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0019207 kinase regulator activity; GO:0004672 protein kinase activity; GO:0004721 phosphoprotein phosphatase activity; GO:0098772 molecular function regulator; GO:0004702 signal transducer, downstream of receptor, with serine/threonine kinase activity; GO:0004871 signal transducer activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0019209 kinase activator activity; GO:0016301 kinase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0008022 protein C-terminus binding; GO:0043168 anion binding; GO:0004708 MAP kinase kinase activity; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016740 transferase activity; GO:0008047 enzyme activator activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0043539 protein serine/threonine kinase activator activity; GO:0030295 protein kinase activator activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0019887 protein kinase regulator activity; GO:0000166 nucleotide binding; GO:0004712 protein serine/threonine/tyrosine kinase activity; GO:0032549 ribonucleoside binding; GO:0005057 signal transducer activity, downstream of receptor; GO:0097367 carbohydrate derivative binding; GO:0030234 enzyme regulator activity; GO:0042578 phosphoric ester hydrolase activity; GO:0004725 protein tyrosine phosphatase activity; GO:0016788 hydrolase activity, acting on ester bonds; GO:0004674 protein serine/threonine kinase activity; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K04368","MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]","hsa04662 B cell receptor signaling pathway - Homo sapiens (human); hsa05220 Chronic myeloid leukemia - Homo sapiens (human); hsa04014 Ras signaling pathway - Homo sapiens (human); hsa04150 mTOR signaling pathway - Homo sapiens (human); hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa05206 MicroRNAs in cancer - Homo sapiens (human); hsa05164 Influenza A - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa04934 Cushing's syndrome - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa04917 Prolactin signaling pathway - Homo sapiens (human); hsa05161 Hepatitis B - Homo sapiens (human); hsa05215 Prostate cancer - Homo sapiens (human); hsa01521 EGFR tyrosine kinase inhibitor resistance - Homo sapiens (human); hsa04914 Progesterone-mediated oocyte maturation - Homo sapiens (human); hsa04725 Cholinergic synapse - Homo sapiens (human); hsa04921 Oxytocin signaling pathway - Homo sapiens (human); hsa04218 Cellular senescence - Homo sapiens (human); hsa04722 Neurotrophin signaling pathway - Homo sapiens (human); hsa04371 Apelin signaling pathway - Homo sapiens (human); hsa04916 Melanogenesis - Homo sapiens (human); hsa04270 Vascular smooth muscle contraction - Homo sapiens (human); hsa05167 Kaposi's sarcoma-associated herpesvirus infection - Homo sapiens (human); hsa04010 MAPK signaling pathway - Homo sapiens (human); hsa05219 Bladder cancer - Homo sapiens (human); hsa04664 Fc epsilon RI signaling pathway - Homo sapiens (human); hsa04540 Gap junction - Homo sapiens (human); hsa04912 GnRH signaling pathway - Homo sapiens (human); hsa04668 TNF signaling pathway - Homo sapiens (human); hsa05020 Prion diseases - Homo sapiens (human); hsa04730 Long-term depression - Homo sapiens (human); hsa05226 Gastric cancer - Homo sapiens (human); hsa04720 Long-term potentiation - Homo sapiens (human); hsa04928 Parathyroid hormone synthesis, secretion and action - Homo sapiens (human); hsa05218 Melanoma - Homo sapiens (human); hsa05212 Pancreatic cancer - Homo sapiens (human); hsa04550 Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human); hsa04015 Rap1 signaling pathway - Homo sapiens (human); hsa04072 Phospholipase D signaling pathway - Homo sapiens (human); hsa04650 Natural killer cell mediated cytotoxicity - Homo sapiens (human); hsa05221 Acute myeloid leukemia - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa05230 Central carbon metabolism in cancer - Homo sapiens (human); hsa04140 Autophagy - animal - Homo sapiens (human); hsa04114 Oocyte meiosis - Homo sapiens (human); hsa04380 Osteoclast differentiation - Homo sapiens (human); hsa04071 Sphingolipid signaling pathway - Homo sapiens (human); hsa05213 Endometrial cancer - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa05224 Breast cancer - Homo sapiens (human); hsa01522 Endocrine resistance - Homo sapiens (human); hsa05034 Alcoholism - Homo sapiens (human); hsa05210 Colorectal cancer - Homo sapiens (human); hsa04915 Estrogen signaling pathway - Homo sapiens (human); hsa05216 Thyroid cancer - Homo sapiens (human); hsa05231 Choline metabolism in cancer - Homo sapiens (human); hsa04620 Toll-like receptor signaling pathway - Homo sapiens (human); hsa04210 Apoptosis - Homo sapiens (human); hsa04370 VEGF signaling pathway - Homo sapiens (human); hsa04910 Insulin signaling pathway - Homo sapiens (human); hsa05211 Renal cell carcinoma - Homo sapiens (human); hsa05225 Hepatocellular carcinoma - Homo sapiens (human); hsa04024 cAMP signaling pathway - Homo sapiens (human); hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa04660 T cell receptor signaling pathway - Homo sapiens (human); hsa04726 Serotonergic synapse - Homo sapiens (human); hsa04062 Chemokine signaling pathway - Homo sapiens (human); hsa05223 Non-small cell lung cancer - Homo sapiens (human); hsa04666 Fc gamma R-mediated phagocytosis - Homo sapiens (human); hsa04066 HIF-1 signaling pathway - Homo sapiens (human); hsa04068 FoxO signaling pathway - Homo sapiens (human); hsa05214 Glioma - Homo sapiens (human); hsa04012 ErbB signaling pathway - Homo sapiens (human); hsa04926 Relaxin signaling pathway - Homo sapiens (human); ","IPR000719; IPR011009; ","Protein kinase domain; Protein kinase-like domain; \r"]
["Q02818","Nucleobindin-1 OS=Homo sapiens OX=9606 GN=NUCB1","NUCB1",53.879,96.764,51.2,20,33,20,0.99,0.97,0.962,0.998,1.026,1.029,1.045,0.0277,"endoplasmic reticulum\r","GO:0072718 response to cisplatin; GO:1903533 regulation of protein targeting; GO:0051049 regulation of transport; GO:0032386 regulation of intracellular transport; GO:0050896 response to stimulus; GO:0070201 regulation of establishment of protein localization; GO:0060341 regulation of cellular localization; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032879 regulation of localization; GO:0051223 regulation of protein transport; GO:0032880 regulation of protein localization; GO:0033157 regulation of intracellular protein transport; GO:1903827 regulation of cellular protein localization; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0019898 extrinsic component of membrane; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0031982 vesicle; GO:0005801 cis-Golgi network; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0090498 extrinsic component of Golgi membrane; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0098791 Golgi subcompartment; GO:0044431 Golgi apparatus part; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0098547 lumenal side of Golgi membrane; GO:0098552 side of membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0032580 Golgi cisterna membrane; GO:0005791 rough endoplasmic reticulum; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0005795 Golgi stack; GO:0012505 endomembrane system; GO:0005798 Golgi-associated vesicle; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005793 endoplasmic reticulum-Golgi intermediate compartment; GO:0005802 trans-Golgi network; GO:0098576 lumenal side of membrane; GO:0031312 extrinsic component of organelle membrane; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0031985 Golgi cisterna; GO:0031984 organelle subcompartment; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003677 DNA binding; GO:0005488 binding; GO:0043167 ion binding; GO:0003676 nucleic acid binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0001965 G-protein alpha-subunit binding; GO:0005509 calcium ion binding; ","K20371",null,null,"IPR011992; IPR002048; ","EF-hand domain pair; EF-hand domain; \r"]
["Q02878","60S ribosomal protein L6 OS=Homo sapiens OX=9606 GN=RPL6","RPL6",32.728,25.697,29.2,10,18,10,0.98,0.869,0.89,1.081,1.102,1.097,1.198,0.0395,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0006518 peptide metabolic process; GO:0022618 ribonucleoprotein complex assembly; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0042273 ribosomal large subunit biogenesis; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0002181 cytoplasmic translation; GO:0070972 protein localization to endoplasmic reticulum; GO:0006364 rRNA processing; GO:0065003 macromolecular complex assembly; GO:0033365 protein localization to organelle; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0008104 protein localization; GO:0006396 RNA processing; GO:0018130 heterocycle biosynthetic process; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0072657 protein localization to membrane; GO:0080090 regulation of primary metabolic process; GO:0042254 ribosome biogenesis; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032774 RNA biosynthetic process; GO:0045047 protein targeting to ER; GO:0031323 regulation of cellular metabolic process; GO:0051704 multi-organism process; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0044267 cellular protein metabolic process; GO:0048519 negative regulation of biological process; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0051171 regulation of nitrogen compound metabolic process; GO:0044248 cellular catabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0034613 cellular protein localization; GO:0090150 establishment of protein localization to membrane; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0042255 ribosome assembly; GO:0045184 establishment of protein localization; GO:0006996 organelle organization; GO:0051179 localization; GO:1901564 organonitrogen compound metabolic process; GO:0072594 establishment of protein localization to organelle; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:2001141 regulation of RNA biosynthetic process; GO:0006612 protein targeting to membrane; GO:0051649 establishment of localization in cell; GO:0000027 ribosomal large subunit assembly; GO:0071826 ribonucleoprotein complex subunit organization; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0022607 cellular component assembly; GO:0006413 translational initiation; GO:1901361 organic cyclic compound catabolic process; GO:0006412 translation; GO:0033036 macromolecule localization; GO:0034470 ncRNA processing; GO:0016072 rRNA metabolic process; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0043043 peptide biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0006401 RNA catabolic process; GO:0016070 RNA metabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0019222 regulation of metabolic process; GO:0019083 viral transcription; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0019058 viral life cycle; GO:0006613 cotranslational protein targeting to membrane; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0070925 organelle assembly; GO:0016032 viral process; GO:0006886 intracellular protein transport; GO:0019080 viral gene expression; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0034622 cellular macromolecular complex assembly; GO:0044265 cellular macromolecule catabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0051641 cellular localization; GO:0070727 cellular macromolecule localization; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0009056 catabolic process; GO:0034660 ncRNA metabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:0046700 heterocycle catabolic process; ","GO:0016020 membrane; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005925 focal adhesion; GO:0044391 ribosomal subunit; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:0030055 cell-substrate junction; GO:0044445 cytosolic part; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0022626 cytosolic ribosome; GO:0043229 intracellular organelle; GO:0005840 ribosome; GO:0043232 intracellular non-membrane-bounded organelle; GO:0022625 cytosolic large ribosomal subunit; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0005829 cytosol; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0015934 large ribosomal subunit; GO:0035770 ribonucleoprotein granule; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0050839 cell adhesion molecule binding; GO:0003677 DNA binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0005198 structural molecule activity; GO:0003735 structural constituent of ribosome; ","K02934","RP-L6e; large subunit ribosomal protein L6e","hsa03010 Ribosome - Homo sapiens (human); ","IPR005568; IPR008991; IPR014722; ","\"Ribosomal protein L6, N-terminal; Translation protein SH3-like domain; Ribosomal protein L2 domain 2; \"\r"]
["Q03001","Dystonin OS=Homo sapiens OX=9606 GN=DST","DST",860.65,45.842,1.1,8,8,7,1.02,1.013,1.022,0.969,1.001,0.991,0.969,0.0348,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0034329 cell junction assembly; GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0051674 localization of cell; GO:0007166 cell surface receptor signaling pathway; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0008090 retrograde axonal transport; GO:0030705 cytoskeleton-dependent intracellular transport; GO:0099111 microtubule-based transport; GO:0051234 establishment of localization; GO:0009611 response to wounding; GO:0022610 biological adhesion; GO:0007165 signal transduction; GO:0010970 transport along microtubule; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:1902578 single-organism localization; GO:0022607 cellular component assembly; GO:0007155 cell adhesion; GO:1902580 single-organism cellular localization; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0030011 maintenance of cell polarity; GO:0044765 single-organism transport; GO:0007044 cell-substrate junction assembly; GO:0051716 cellular response to stimulus; GO:0045104 intermediate filament cytoskeleton organization; GO:0006950 response to stress; GO:0045103 intermediate filament-based process; GO:0098930 axonal transport; GO:0044763 single-organism cellular process; GO:0048870 cell motility; GO:0007163 establishment or maintenance of cell polarity; GO:0007229 integrin-mediated signaling pathway; GO:0023052 signaling; GO:0007017 microtubule-based process; GO:1902582 single-organism intracellular transport; GO:0051641 cellular localization; GO:0006810 transport; GO:0000226 microtubule cytoskeleton organization; GO:1902589 single-organism organelle organization; GO:0007018 microtubule-based movement; GO:0008088 axo-dendritic transport; GO:0050789 regulation of biological process; GO:0034330 cell junction organization; GO:0031581 hemidesmosome assembly; GO:0006996 organelle organization; GO:0006928 movement of cell or subcellular component; GO:0040011 locomotion; GO:0051179 localization; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0035371 microtubule plus-end; GO:0099568 cytoplasmic region; GO:0005737 cytoplasm; GO:0032838 cell projection cytoplasm; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0031674 I band; GO:0044422 organelle part; GO:0005604 basement membrane; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0098590 plasma membrane region; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0043005 neuron projection; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0005789 endoplasmic reticulum membrane; GO:0005924 cell-substrate adherens junction; GO:0031252 cell leading edge; GO:0042995 cell projection; GO:0099513 polymeric cytoskeletal fiber; GO:0044430 cytoskeletal part; GO:0031967 organelle envelope; GO:0070161 anchoring junction; GO:0005576 extracellular region; GO:0033267 axon part; GO:0005886 plasma membrane; GO:0099081 supramolecular polymer; GO:0030424 axon; GO:0031012 extracellular matrix; GO:0043231 intracellular membrane-bounded organelle; GO:1904115 axon cytoplasm; GO:0045111 intermediate filament cytoskeleton; GO:0005882 intermediate filament; GO:0031975 envelope; GO:0031672 A band; GO:0044449 contractile fiber part; GO:0043230 extracellular organelle; GO:0016323 basolateral plasma membrane; GO:0005783 endoplasmic reticulum; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005938 cell cortex; GO:0005874 microtubule; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0030016 myofibril; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0099512 supramolecular fiber; GO:1990752 microtubule end; GO:0030018 Z disc; GO:0044420 extracellular matrix component; GO:0005856 cytoskeleton; GO:0015630 microtubule cytoskeleton; GO:0044464 cell part; GO:0044425 membrane part; GO:0043292 contractile fiber; GO:1903561 extracellular vesicle; GO:0005912 adherens junction; GO:0030056 hemidesmosome; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0031673 H zone; GO:0005635 nuclear envelope; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044463 cell projection part; GO:0005829 cytosol; GO:0016021 integral component of membrane; GO:0015629 actin cytoskeleton; GO:0043226 organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0044432 endoplasmic reticulum part; GO:0030017 sarcomere; GO:0009925 basal plasma membrane; GO:0005578 proteinaceous extracellular matrix; GO:0044444 cytoplasmic part; GO:0045178 basal part of cell; GO:0044428 nuclear part; ","GO:0005102 receptor binding; GO:0043167 ion binding; GO:0046983 protein dimerization activity; GO:0044877 macromolecular complex binding; GO:0015631 tubulin binding; GO:0005515 protein binding; GO:0005178 integrin binding; GO:0051010 microtubule plus-end binding; GO:0050839 cell adhesion molecule binding; GO:0008092 cytoskeletal protein binding; GO:0042802 identical protein binding; GO:0005488 binding; GO:0008017 microtubule binding; GO:0042803 protein homodimerization activity; GO:0003779 actin binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0008022 protein C-terminus binding; GO:0005509 calcium ion binding; GO:0032403 protein complex binding; ","K10382",null,null,"IPR003108; IPR011992; IPR002048; IPR001715; ","Gas2-related domain; EF-hand domain pair; EF-hand domain; Calponin homology domain; \r"]
["Q03013","Glutathione S-transferase Mu 4 OS=Homo sapiens OX=9606 GN=GSTM4","GSTM4",25.561,18.378,53.7,12,20,3,0.735,0.795,0.702,1.245,1.197,1.2,1.632,0.000219,"cytoplasm\r","GO:0071466 cellular response to xenobiotic stimulus; GO:0006518 peptide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0044272 sulfur compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:1901685 glutathione derivative metabolic process; GO:0008152 metabolic process; GO:0006575 cellular modified amino acid metabolic process; GO:0009410 response to xenobiotic stimulus; GO:0006805 xenobiotic metabolic process; GO:0006749 glutathione metabolic process; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009987 cellular process; GO:0070887 cellular response to chemical stimulus; GO:0006790 sulfur compound metabolic process; GO:0051716 cellular response to stimulus; GO:0044711 single-organism biosynthetic process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:0043603 cellular amide metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:1901687 glutathione derivative biosynthetic process; GO:0042178 xenobiotic catabolic process; GO:0042221 response to chemical; GO:0044710 single-organism metabolic process; GO:0009056 catabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0044444 cytoplasmic part; ","GO:0043167 ion binding; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:0033218 amide binding; GO:0043295 glutathione binding; GO:1900750 oligopeptide binding; GO:1901681 sulfur compound binding; GO:0004364 glutathione transferase activity; GO:0042802 identical protein binding; GO:0072341 modified amino acid binding; GO:0003824 catalytic activity; GO:0042277 peptide binding; GO:0005488 binding; GO:0042803 protein homodimerization activity; GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups; GO:0043168 anion binding; GO:0016740 transferase activity; GO:0019899 enzyme binding; ","K00799","GST; glutathione S-transferase [EC:2.5.1.18]","hsa01524 Platinum drug resistance - Homo sapiens (human); hsa00480 Glutathione metabolism - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa05204 Chemical carcinogenesis - Homo sapiens (human); hsa00980 Metabolism of xenobiotics by cytochrome P450 - Homo sapiens (human); hsa05225 Hepatocellular carcinoma - Homo sapiens (human); hsa00983 Drug metabolism - other enzymes - Homo sapiens (human); hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human); hsa00982 Drug metabolism - cytochrome P450 - Homo sapiens (human); hsa05215 Prostate cancer - Homo sapiens (human); ","IPR004046; IPR010987; IPR004045; IPR012336; ","\"Glutathione S-transferase, C-terminal; Glutathione S-transferase, C-terminal-like; Glutathione S-transferase, N-terminal; Thioredoxin-like fold; \"\r"]
["Q03154","Aminoacylase-1 OS=Homo sapiens OX=9606 GN=ACY1","ACY1",45.884,34.531,22.3,6,10,6,1.033,1.083,0.983,0.993,0.937,1.072,0.969,0.535,"cytoplasm\r","GO:0071466 cellular response to xenobiotic stimulus; GO:0051716 cellular response to stimulus; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0042221 response to chemical; GO:0006520 cellular amino acid metabolic process; GO:0006805 xenobiotic metabolic process; GO:0009410 response to xenobiotic stimulus; GO:0044710 single-organism metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0006508 proteolysis; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006082 organic acid metabolic process; GO:0009987 cellular process; GO:0070887 cellular response to chemical stimulus; GO:0043436 oxoacid metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0008233 peptidase activity; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0008237 metallopeptidase activity; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0004046 aminoacylase activity; GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; ","K14677","ACY1; aminoacylase [EC:3.5.1.14]","hsa00220 Arginine biosynthesis - Homo sapiens (human); hsa01210 2-Oxocarboxylic acid metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa01230 Biosynthesis of amino acids - Homo sapiens (human); ","IPR011650; ","\"Peptidase M20, dimerisation domain; \"\r"]
["Q03426","Mevalonate kinase OS=Homo sapiens OX=9606 GN=MVK","MVK",42.45,19.286,13.4,4,6,4,1.078,1.098,1.132,0.964,0.877,0.874,0.821,0.00484,"extracellular\r","GO:0016310 phosphorylation; GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway; GO:1901615 organic hydroxy compound metabolic process; GO:1902652 secondary alcohol metabolic process; GO:0050728 negative regulation of inflammatory response; GO:0006066 alcohol metabolic process; GO:1902653 secondary alcohol biosynthetic process; GO:0008654 phospholipid biosynthetic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0009058 biosynthetic process; GO:0080134 regulation of response to stress; GO:0048519 negative regulation of biological process; GO:0031347 regulation of defense response; GO:0016125 sterol metabolic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0008610 lipid biosynthetic process; GO:0008299 isoprenoid biosynthetic process; GO:0016126 sterol biosynthetic process; GO:0008152 metabolic process; GO:0006695 cholesterol biosynthetic process; GO:0046490 isopentenyl diphosphate metabolic process; GO:0032102 negative regulation of response to external stimulus; GO:0009987 cellular process; GO:0031348 negative regulation of defense response; GO:0006629 lipid metabolic process; GO:0006790 sulfur compound metabolic process; GO:0006720 isoprenoid metabolic process; GO:0008203 cholesterol metabolic process; GO:0044711 single-organism biosynthetic process; GO:0044281 small molecule metabolic process; GO:0008202 steroid metabolic process; GO:0035383 thioester metabolic process; GO:0044763 single-organism cellular process; GO:0046165 alcohol biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:1901617 organic hydroxy compound biosynthetic process; GO:0032101 regulation of response to external stimulus; GO:0006732 coenzyme metabolic process; GO:0048585 negative regulation of response to stimulus; GO:0006084 acetyl-CoA metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0006637 acyl-CoA metabolic process; GO:0044249 cellular biosynthetic process; GO:0051186 cofactor metabolic process; GO:0006694 steroid biosynthetic process; GO:0090407 organophosphate biosynthetic process; GO:0050789 regulation of biological process; GO:0009240 isopentenyl diphosphate biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:0044283 small molecule biosynthetic process; GO:0050727 regulation of inflammatory response; GO:0019637 organophosphate metabolic process; GO:0006644 phospholipid metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0065007 biological regulation; ","GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0004496 mevalonate kinase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0042802 identical protein binding; GO:0016301 kinase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0016740 transferase activity; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K00869","E2.7.1.36; mevalonate kinase [EC:2.7.1.36]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00900 Terpenoid backbone biosynthesis - Homo sapiens (human); hsa04146 Peroxisome - Homo sapiens (human); ","IPR020568; IPR006204; IPR014721; IPR013750; ","\"Ribosomal protein S5 domain 2-type fold; GHMP kinase N-terminal domain; Ribosomal protein S5 domain 2-type fold, subgroup; GHMP kinase, C-terminal domain; \"\r"]
["Q04206","Transcription factor p65 OS=Homo sapiens OX=9606 GN=RELA","RELA",60.218,8.9451,6.2,3,3,3,1.029,0.982,1.049,0.915,1.051,0.982,0.963,0.436,"nucleus\r",{"$cut":{"chars":16935,"head":"GO:0044700 single organism signaling; GO:0035094 response to nicotine; GO:0010941 regulation of cell death; GO:0048732 gland development; GO:0014013 regulation of gliogenesis; GO:0098542 defense response to other organism; GO:0009891 positive regulation of biosynthetic process; GO:0046683 response to organophosphorus; GO:0035872 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; GO:0070555 response to interleukin-1; GO:0031347 regulation of defense response; GO:0044237 cellular metabolic process; GO:0009607 response to biotic stimulus; GO:0008152 metabolic process; GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling; GO:0044093 positive regulation of molecular function; GO:0030522 intracellular receptor signaling pathway; GO:0014072 response to isoquinoline alkaloid; GO:0008544 epidermis development; GO:0051716 cellular response to stimulus; GO:0043588 skin development; GO:0060359 response to ammonium ion; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0071396 cellular response to lipid; GO:0051704 multi-organism process; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0050776 regulation of immune response; GO:0010243 response to organonitrogen compound; GO:0051092 positive regulation of NF-kappaB transcription factor activity; GO:1902532 negative regulation of intracellular signal transduction; GO:0002223 stimulatory C-type lectin receptor signaling pathway; GO:0051591 response to cAMP; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:1901698 response to nitrogen compound; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0060548 negative regulation of cell death; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:1900077 negative regulation of cellular response to insulin stimulus; GO:0044707 single-multicellular organism process; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0042303 molting cycle; GO:0001819 positive regulation of cytokine production; GO:1901700 response to oxygen-containing compound; GO:0046627 negative regulation of insulin receptor signaling pathway; GO:0071354 cellular response to interleukin-6; GO:0048519 negative regulation of biological process; GO:0045892 negative regulation of transcription, DNA-templated; GO:0042493 response to drug; GO:0009653 anatomical structure morphogenesis; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0042176 regulation of protein catabolic process; GO:0038093 Fc receptor signaling pathway; GO:0050778 positive regulation of immune response; GO:0009416 response to light stimulus; GO:0006950 response to stress; GO:0032496 response to lipopolysaccharide; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0032332 positive regulation of chondrocyte differentiation; GO:0032101 regulation of response to external stimulus; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0007584 response to nutrient; GO:0042633 hair cycle; GO:1901576 organic substance biosynthetic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0001889 liver development; GO:0009890 negative regulation of biosynthetic process; GO:0042542 response to hydrogen peroxide; GO:0031325 positive regulation of cellular metabolic process; GO:0014040 positive regulation of Schwann cell differentiation; GO:0071219 cellular response to molecule of bacterial origin; GO:0008284 positive regulation of cell proliferation; GO:0071316 cellular "}},"GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0071159 NF-kappaB complex; GO:0005623 cell; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044454 nuclear chromosome part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0000790 nuclear chromatin; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0033256 I-kappaB/NF-kappaB complex; GO:0031981 nuclear lumen; GO:0005667 transcription factor complex; GO:0005829 cytosol; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0000785 chromatin; GO:0000228 nuclear chromosome; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding; GO:0047485 protein N-terminus binding; GO:0001158 enhancer sequence-specific DNA binding; GO:0031490 chromatin DNA binding; GO:0031625 ubiquitin protein ligase binding; GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding; GO:0003690 double-stranded DNA binding; GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding; GO:0019901 protein kinase binding; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:0003682 chromatin binding; GO:0035326 enhancer binding; GO:0000987 core promoter proximal region sequence-specific DNA binding; GO:0033613 activating transcription factor binding; GO:0003700 transcription factor activity, sequence-specific DNA binding; GO:0001047 core promoter binding; GO:1901363 heterocyclic compound binding; GO:0000975 regulatory region DNA binding; GO:0097159 organic cyclic compound binding; GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding; GO:0001046 core promoter sequence-specific DNA binding; GO:0008092 cytoskeletal protein binding; GO:0042802 identical protein binding; GO:0042826 histone deacetylase binding; GO:0070491 repressing transcription factor binding; GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific; GO:0005488 binding; GO:0042805 actinin binding; GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding; GO:0001071 nucleic acid binding transcription factor activity; GO:0043168 anion binding; GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding; GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding; GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding; GO:0003677 DNA binding; GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding; GO:0046982 protein heterodimerization activity; GO:0000976 transcription regulatory region sequence-specific DNA binding; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0001012 RNA polymerase II regulatory region DNA binding; GO:1990837 sequence-specific double-stranded DNA binding; GO:0042301 phosphate ion binding; GO:0019900 kinase binding; GO:0043565 sequence-specific DNA binding; GO:0001159 core promoter proximal region DNA binding; GO:0001067 regulatory region nucleic acid binding; GO:0044212 transcription regulatory region DNA binding; GO:0042803 protein homodimerization activity; GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding; GO:0003676 nucleic acid binding; GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding; GO:0019904 protein domain specific binding; GO:0051059 NF-kappaB binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0071532 ankyrin repeat binding; GO:0019899 enzyme binding; GO:0008134 transcription factor binding; GO:0032403 protein complex binding; ","K04735","RELA; transcription factor p65","hsa05152 Tuberculosis - Homo sapiens (human); hsa05221 Acute myeloid leukemia - Homo sapiens (human); hsa04625 C-type lectin receptor signaling pathway - Homo sapiens (human); hsa04662 B cell receptor signaling pathway - Homo sapiens (human); hsa05220 Chronic myeloid leukemia - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa04014 Ras signaling pathway - Homo sapiens (human); hsa05222 Small cell lung cancer - Homo sapiens (human); hsa05162 Measles - Homo sapiens (human); hsa05166 HTLV-I infection - Homo sapiens (human); hsa05131 Shigellosis - Homo sapiens (human); hsa04931 Insulin resistance - Homo sapiens (human); hsa05145 Toxoplasmosis - Homo sapiens (human); hsa05164 Influenza A - Homo sapiens (human); hsa04920 Adipocytokine signaling pathway - Homo sapiens (human); hsa04380 Osteoclast differentiation - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa04071 Sphingolipid signaling pathway - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa04933 AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human); hsa04659 Th17 cell differentiation - Homo sapiens (human); hsa05321 Inflammatory bowel disease (IBD) - Homo sapiens (human); hsa04211 Longevity regulating pathway - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa04917 Prolactin signaling pathway - Homo sapiens (human); hsa05161 Hepatitis B - Homo sapiens (human); hsa05215 Prostate cancer - Homo sapiens (human); hsa04064 NF-kappa B signaling pathway - Homo sapiens (human); hsa05120 Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human); hsa05142 Chagas disease (American trypanosomiasis) - Homo sapiens (human); hsa05132 Salmonella infection - Homo sapiens (human); hsa04218 Cellular senescence - Homo sapiens (human); hsa04620 Toll-like receptor signaling pathway - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); hsa05168 Herpes simplex infection - Homo sapiens (human); hsa04210 Apoptosis - Homo sapiens (human); hsa04722 Neurotrophin signaling pathway - Homo sapiens (human); hsa05160 Hepatitis C - Homo sapiens (human); hsa04137 Mitophagy - animal - Homo sapiens (human); hsa05140 Leishmaniasis - Homo sapiens (human); hsa05167 Kaposi's sarcoma-associated herpesvirus infection - Homo sapiens (human); hsa04024 cAMP signaling pathway - Homo sapiens (human); hsa01523 Antifolate resistance - Homo sapiens (human); hsa05134 Legionellosis - Homo sapiens (human); hsa04010 MAPK signaling pathway - Homo sapiens (human); hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human); hsa05030 Cocaine addiction - Homo sapiens (human); hsa04660 T cell receptor signaling pathway - Homo sapiens (human); hsa04658 Th1 and Th2 cell differentiation - Homo sapiens (human); hsa04062 Chemokine signaling pathway - Homo sapiens (human); hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human); hsa04657 IL-17 signaling pathway - Homo sapiens (human); hsa04066 HIF-1 signaling pathway - Homo sapiens (human); hsa05146 Amoebiasis - Homo sapiens (human); hsa04668 TNF signaling pathway - Homo sapiens (human); hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human); hsa05203 Viral carcinogenesis - Homo sapiens (human); hsa04623 Cytosolic DNA-sensing pathway - Homo sapiens (human); hsa05133 Pertussis - Homo sapiens (human); hsa04622 RIG-I-like receptor signaling pathway - Homo sapiens (human); hsa04926 Relaxin signaling pathway - Homo sapiens (human); hsa05212 Pancreatic cancer - Homo sapiens (human); ","IPR013783; IPR014756; IPR008967; IPR032397; IPR011539; IPR033926; IPR002909; ","\"Immunoglobulin-like fold; Immunoglobulin E-set; p53-like transcription factor, DNA-binding; Rel homology dimerisation domain; Rel homology domain (RHD), DNA-binding domain; NFkappaB IPT domain; IPT domain; \"\r"]
["Q04446","1,4-alpha-glucan-branching enzyme OS=Homo sapiens OX=9606 GN=GBE1","GBE1",80.473,50.926,15.5,10,14,10,1.172,1.091,1.044,0.954,0.871,0.92,0.83,0.0123,"nucleus\r","GO:0016051 carbohydrate biosynthetic process; GO:0000271 polysaccharide biosynthetic process; GO:0044042 glucan metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0006112 energy reserve metabolic process; GO:0044237 cellular metabolic process; GO:0044264 cellular polysaccharide metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0044262 cellular carbohydrate metabolic process; GO:0005976 polysaccharide metabolic process; GO:0005978 glycogen biosynthetic process; GO:0043170 macromolecule metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0034637 cellular carbohydrate biosynthetic process; GO:0009987 cellular process; GO:0006073 cellular glucan metabolic process; GO:0044711 single-organism biosynthetic process; GO:0055114 oxidation-reduction process; GO:0044763 single-organism cellular process; GO:0005977 glycogen metabolic process; GO:0033692 cellular polysaccharide biosynthetic process; GO:0044238 primary metabolic process; GO:0005975 carbohydrate metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0009250 glucan biosynthetic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0044260 cellular macromolecule metabolic process; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0003844 1,4-alpha-glucan branching enzyme activity; GO:0016758 transferase activity, transferring hexosyl groups; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016798 hydrolase activity, acting on glycosyl bonds; GO:0043167 ion binding; GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds; GO:0043169 cation binding; GO:0030246 carbohydrate binding; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0016757 transferase activity, transferring glycosyl groups; GO:0016740 transferase activity; ","K00700","GBE1; 1,4-alpha-glucan branching enzyme [EC:2.4.1.18]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00500 Starch and sucrose metabolism - Homo sapiens (human); ","IPR004193; IPR014756; IPR006048; IPR017853; IPR013783; IPR013780; IPR006047; IPR013781; ","\"Glycoside hydrolase, family 13, N-terminal; Immunoglobulin E-set; Alpha-amylase/branching enzyme, C-terminal all beta; Glycoside hydrolase superfamily; Immunoglobulin-like fold; Glycosyl hydrolase, all-beta; Glycosyl hydrolase, family 13, catalytic domain; Glycoside hydrolase, catalytic domain; \"\r"]
["Q04760","Lactoylglutathione lyase OS=Homo sapiens OX=9606 GN=GLO1","GLO1",20.777,28.169,27.7,6,16,6,1.021,1.033,1.04,0.966,0.959,0.986,0.941,0.00352,"cytoplasm\r","GO:0010941 regulation of cell death; GO:0006518 peptide metabolic process; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0042180 cellular ketone metabolic process; GO:0006749 glutathione metabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0006790 sulfur compound metabolic process; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0002521 leukocyte differentiation; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006081 cellular aldehyde metabolic process; GO:0002520 immune system development; GO:0043603 cellular amide metabolic process; GO:0005975 carbohydrate metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0044710 single-organism metabolic process; GO:0019222 regulation of metabolic process; GO:0006082 organic acid metabolic process; GO:0060548 negative regulation of cell death; GO:0048856 anatomical structure development; GO:0009438 methylglyoxal metabolic process; GO:0043436 oxoacid metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0030316 osteoclast differentiation; GO:0043069 negative regulation of programmed cell death; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0043067 regulation of programmed cell death; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0006090 pyruvate metabolic process; GO:0006575 cellular modified amino acid metabolic process; GO:0043066 negative regulation of apoptotic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0006355 regulation of transcription, DNA-templated; GO:0030099 myeloid cell differentiation; GO:0048731 system development; GO:0006807 nitrogen compound metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0048534 hematopoietic or lymphoid organ development; GO:0030097 hemopoiesis; GO:0044767 single-organism developmental process; GO:0002573 myeloid leukocyte differentiation; GO:0019752 carboxylic acid metabolic process; GO:0042981 regulation of apoptotic process; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0004462 lactoylglutathione lyase activity; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0016829 lyase activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0016846 carbon-sulfur lyase activity; GO:0008270 zinc ion binding; ","K01759","GLO1; lactoylglutathione lyase [EC:4.4.1.5]","hsa00620 Pyruvate metabolism - Homo sapiens (human); ","IPR029068; IPR004360; ","Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase; Glyoxalase/fosfomycin resistance/dioxygenase domain; \r"]
["Q04917","14-3-3 protein eta OS=Homo sapiens OX=9606 GN=YWHAH","YWHAH",28.218,51.975,39.8,10,37,8,1.041,1.029,0.993,1.024,0.917,0.989,0.957,0.272,"cytoplasm\r","GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0065008 regulation of biological quality; GO:2000171 negative regulation of dendrite development; GO:0007420 brain development; GO:0009891 positive regulation of biosynthetic process; GO:0010821 regulation of mitochondrion organization; GO:0015031 protein transport; GO:0048857 neural nucleus development; GO:0021762 substantia nigra development; GO:0008152 metabolic process; GO:0050774 negative regulation of dendrite morphogenesis; GO:1901028 regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; GO:1903747 regulation of establishment of protein localization to mitochondrion; GO:0032879 regulation of localization; GO:0030522 intracellular receptor signaling pathway; GO:0048545 response to steroid hormone; GO:0009719 response to endogenous stimulus; GO:0090559 regulation of membrane permeability; GO:0008104 protein localization; GO:0030518 intracellular steroid hormone receptor signaling pathway; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0014070 response to organic cyclic compound; GO:0030901 midbrain development; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044763 single-organism cellular process; GO:0008202 steroid metabolic process; GO:0043269 regulation of ion transport; GO:2000649 regulation of sodium ion transmembrane transporter activity; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0071396 cellular response to lipid; GO:0050768 negative regulation of neurogenesis; GO:0006810 transport; GO:0034762 regulation of transmembrane transport; GO:1901575 organic substance catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0042921 glucocorticoid receptor signaling pathway; GO:0007417 central nervous system development; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:0045665 negative regulation of neuron differentiation; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0010721 negative regulation of cell development; GO:0051899 membrane depolarization; GO:0032412 regulation of ion transmembrane transporter activity; GO:0010975 regulation of neuron projection development; GO:0043068 positive regulation of programmed cell death; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0044707 single-multicellular organism process; GO:0002028 regulation of sodium ion transport; GO:0007006 mitochondrial membrane organization; GO:0043067 regulation of programmed cell death; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:1905477 positive regulation of protein localization to membrane; GO:0048814 regulation of dendrite morphogenesis; GO:0051239 regulation of multicellular organismal process; GO:0060341 regulation of cellular localization; GO:1900740 positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0031345 negative regulation of cell projection organization; GO:0010959 regulation of metal ion transport; GO:0051171 regulation of nitrogen compound metabolic process; GO:1901030 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; GO:1902680 positive regulation of RNA biosynthetic process; GO:0007275 multicellular organism development; GO:0032880 regulation of protein localization; GO:0034613 cellular protein localization; GO:0009966 regulation of signal transduction; GO:0032409 regulation of transporter activity; GO:1904062 regulation of cation transmembrane transport; GO:0048167 regulation of synaptic plasticity; GO:0016042 lipid catabolic process; GO:0010771 negative regulation of cell morphogenesis involved in differentiation; GO:0051254 positive regulation of RNA metabolic process; GO:0048731 system development; GO:0050804 modulation of synaptic transmission; GO:0051960 regulation of nervous system development; GO:0060284 regulation of cell development; GO:0071702 organic substance transport; GO:0071407 cellular response to organic cyclic compound; GO:0010977 negative regulation of neuron projection development; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0045184 establishment of protein localization; GO:1904951 positive regulation of establishment of protein localization; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0031325 positive regulation of cellular metabolic process; GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:1902305 regulation of sodium ion transmembrane transport; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:0031328 positive regulation of cellular biosynthetic process; GO:0050793 regulation of developmental process; GO:1903827 regulation of cellular protein localization; GO:0051093 negative regulation of developmental process; GO:0051129 negative regulation of cellular component organization; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:0006839 mitochondrial transport; GO:0022008 neurogenesis; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0006713 glucocorticoid catabolic process; GO:0071383 cellular response to steroid hormone stimulus; GO:1903749 positive regulation of establishment of protein localization to mitochondrion; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:2001141 regulation of RNA biosynthetic process; GO:2001233 regulation of apoptotic signaling pathway; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0007005 mitochondrion organization; GO:1901361 organic cyclic compound catabolic process; GO:0060322 head development; GO:0001508 action potential; GO:0033036 macromolecule localization; GO:0045596 negative regulation of cell differentiation; GO:0070887 cellular response to chemical stimulus; GO:0006629 lipid metabolic process; GO:0008211 glucocorticoid metabolic process; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0022898 regulation of transmembrane transporter activity; GO:0086010 membrane depolarization during action potential; GO:0023052 signaling; GO:0042391 regulation of membrane potential; GO:0010942 positive regulation of cell death; GO:0051050 positive regulation of transport; GO:1902589 single-organism organelle organization; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0045664 regulation of neuron differentiation; GO:0010638 positive regulation of organelle organization; GO:0032870 cellular response to hormone stimulus; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0016043 cellular component organization; GO:0060255 regulation of macromolecule metabolic process; GO:1903829 positive regulation of cellular protein localization; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0043065 positive regulation of apoptotic process; GO:0031344 regulation of cell projection organization; GO:0031958 corticosteroid receptor signaling pathway; GO:0050896 response to stimulus; GO:0070201 regulation of establishment of protein localization; GO:0071704 organic substance metabolic process; GO:0033993 response to lipid; GO:0030154 cell differentiation; GO:1905475 regulation of protein localization to membrane; GO:0046902 regulation of mitochondrial membrane permeability; GO:0051961 negative regulation of nervous system development; GO:0023056 positive regulation of signaling; GO:0006886 intracellular protein transport; GO:2001235 positive regulation of apoptotic signaling pathway; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0006355 regulation of transcription, DNA-templated; GO:0044712 single-organism catabolic process; GO:0051049 regulation of transport; GO:0033043 regulation of organelle organization; GO:0044802 single-organism membrane organization; GO:0010556 regulation of macromolecule biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0009755 hormone-mediated signaling pathway; GO:0051641 cellular localization; GO:0010822 positive regulation of mitochondrion organization; GO:0070727 cellular macromolecule localization; GO:0034765 regulation of ion transmembrane transport; GO:0071495 cellular response to endogenous stimulus; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0006706 steroid catabolic process; GO:0050773 regulation of dendrite development; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0009967 positive regulation of signal transduction; GO:0051128 regulation of cellular component organization; GO:0009725 response to hormone; GO:0043401 steroid hormone mediated signaling pathway; GO:0022604 regulation of cell morphogenesis; GO:0009056 catabolic process; GO:0042981 regulation of apoptotic process; GO:0050767 regulation of neurogenesis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0097708 intracellular vesicle; GO:0016020 membrane; GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0044291 cell-cell contact zone; GO:0031982 vesicle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0012506 vesicle membrane; GO:0044424 intracellular part; GO:0005911 cell-cell junction; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0014704 intercalated disc; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0046982 protein heterodimerization activity; GO:0035259 glucocorticoid receptor binding; GO:0005102 receptor binding; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:0017080 sodium channel regulator activity; GO:0051427 hormone receptor binding; GO:0098772 molecular function regulator; GO:0005159 insulin-like growth factor receptor binding; GO:0008092 cytoskeletal protein binding; GO:0016247 channel regulator activity; GO:0005488 binding; GO:0035257 nuclear hormone receptor binding; GO:0035258 steroid hormone receptor binding; GO:0003779 actin binding; GO:0044325 ion channel binding; GO:0019904 protein domain specific binding; GO:0019899 enzyme binding; ","K16198","YWHAG_H; 14-3-3 protein gamma/eta","hsa04390 Hippo signaling pathway - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa04110 Cell cycle - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); hsa04114 Oocyte meiosis - Homo sapiens (human); hsa05203 Viral carcinogenesis - Homo sapiens (human); ","IPR023410; ","14-3-3 domain; \r"]
["Q05086","Ubiquitin-protein ligase E3A OS=Homo sapiens OX=9606 GN=UBE3A","UBE3A",100.69,41.458,13.9,10,11,10,0.991,1.027,1.045,1.052,1.045,1.005,1.013,0.581,"cytoplasm\r","GO:0044700 single organism signaling; GO:0032270 positive regulation of cellular protein metabolic process; GO:0048732 gland development; GO:0022414 reproductive process; GO:0007420 brain development; GO:0009891 positive regulation of biosynthetic process; GO:0051865 protein autoubiquitination; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0044702 single organism reproductive process; GO:0030522 intracellular receptor signaling pathway; GO:0048545 response to steroid hormone; GO:0009719 response to endogenous stimulus; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:1903362 regulation of cellular protein catabolic process; GO:0030518 intracellular steroid hormone receptor signaling pathway; GO:0044765 single-organism transport; GO:0007399 nervous system development; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0003006 developmental process involved in reproduction; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0009894 regulation of catabolic process; GO:0019953 sexual reproduction; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0031323 regulation of cellular metabolic process; GO:0060736 prostate gland growth; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0071396 cellular response to lipid; GO:0006810 transport; GO:1903506 regulation of nucleic acid-templated transcription; GO:2000058 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:1901575 organic substance catabolic process; GO:0048513 animal organ development; GO:0030163 protein catabolic process; GO:0007417 central nervous system development; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0008585 female gonad development; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0048609 multicellular organismal reproductive process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0000003 reproduction; GO:0044707 single-multicellular organism process; GO:0031399 regulation of protein modification process; GO:0030850 prostate gland development; GO:0008406 gonad development; GO:0044267 cellular protein metabolic process; GO:0042698 ovulation cycle; GO:0000209 protein polyubiquitination; GO:0022602 ovulation cycle process; GO:0046545 development of primary female sexual characteristics; GO:0035265 organ growth; GO:0014066 regulation of phosphatidylinositol 3-kinase signaling; GO:1902578 single-organism localization; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0001541 ovarian follicle development; GO:0051171 regulation of nitrogen compound metabolic process; GO:0007548 sex differentiation; GO:0044248 cellular catabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0042176 regulation of protein catabolic process; GO:0007275 multicellular organism development; GO:0061458 reproductive system development; GO:0009966 regulation of signal transduction; GO:0051254 positive regulation of RNA metabolic process; GO:1902531 regulation of intracellular signal transduction; GO:0016567 protein ubiquitination; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0071407 cellular response to organic cyclic compound; GO:0030162 regulation of proteolysis; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0051247 positive regulation of protein metabolic process; GO:0031398 positive regulation of protein ubiquitination; GO:0032446 protein modification by small protein conjugation; GO:0031325 positive regulation of cellular metabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0048584 positive regulation of response to stimulus; GO:0048589 developmental growth; GO:0051179 localization; GO:0043412 macromolecule modification; GO:0040007 growth; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0046660 female sex differentiation; GO:0071383 cellular response to steroid hormone stimulus; GO:0051234 establishment of localization; GO:0031396 regulation of protein ubiquitination; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0042752 regulation of circadian rhythm; GO:0060322 head development; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0030521 androgen receptor signaling pathway; GO:0035037 sperm entry; GO:0048608 reproductive structure development; GO:0048522 positive regulation of cellular process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0023052 signaling; GO:0009566 fertilization; GO:0001655 urogenital system development; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0032870 cellular response to hormone stimulus; GO:0019222 regulation of metabolic process; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0071310 cellular response to organic substance; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0033993 response to lipid; GO:1903322 positive regulation of protein modification by small protein conjugation or removal; GO:0016032 viral process; GO:0023056 positive regulation of signaling; GO:0006508 proteolysis; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:0045137 development of primary sexual characteristics; GO:0070936 protein K48-linked ubiquitination; GO:0043632 modification-dependent macromolecule catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0019941 modification-dependent protein catabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0031401 positive regulation of protein modification process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0007338 single fertilization; GO:0006897 endocytosis; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0009755 hormone-mediated signaling pathway; GO:0032504 multicellular organism reproduction; GO:0048511 rhythmic process; GO:0044767 single-organism developmental process; GO:0071495 cellular response to endogenous stimulus; GO:0051246 regulation of protein metabolic process; GO:0044703 multi-organism reproductive process; GO:0009057 macromolecule catabolic process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0009967 positive regulation of signal transduction; GO:0009725 response to hormone; GO:0043401 steroid hormone mediated signaling pathway; GO:0009056 catabolic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0000502 proteasome complex; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:1905369 endopeptidase complex; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:1902494 catalytic complex; GO:0005622 intracellular; GO:0044464 cell part; GO:1905368 peptidase complex; GO:0043227 membrane-bounded organelle; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0019787 ubiquitin-like protein transferase activity; GO:0043167 ion binding; GO:0005515 protein binding; GO:0061659 ubiquitin-like protein ligase activity; GO:0003712 transcription cofactor activity; GO:0061630 ubiquitin protein ligase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0004842 ubiquitin-protein transferase activity; GO:0000989 transcription factor activity, transcription factor binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0003713 transcription coactivator activity; GO:0016740 transferase activity; GO:0000988 transcription factor activity, protein binding; ","K10587","UBE3A; ubiquitin-protein ligase E3 A [EC:2.3.2.26]","hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa05203 Viral carcinogenesis - Homo sapiens (human); ","IPR032353; IPR000569; ","\"Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain; HECT domain; \"\r"]
["Q05193","Dynamin-1 OS=Homo sapiens OX=9606 GN=DNM1","DNM1",97.407,17.338,11.2,11,13,6,1.134,1.125,1.078,0.946,0.881,0.901,0.818,0.00154,"cytoplasm\r","GO:0060627 regulation of vesicle-mediated transport; GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0007166 cell surface receptor signaling pathway; GO:1902805 positive regulation of synaptic vesicle transport; GO:0044237 cellular metabolic process; GO:0050877 neurological system process; GO:0007270 neuron-neuron synaptic transmission; GO:0007610 behavior; GO:0099003 vesicle-mediated transport in synapse; GO:0008152 metabolic process; GO:1903421 regulation of synaptic vesicle recycling; GO:0032879 regulation of localization; GO:0065003 macromolecular complex assembly; GO:0043170 macromolecule metabolic process; GO:1903423 positive regulation of synaptic vesicle recycling; GO:0044765 single-organism transport; GO:0051716 cellular response to stimulus; GO:0048489 synaptic vesicle transport; GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway; GO:0044763 single-organism cellular process; GO:0061025 membrane fusion; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0032501 multicellular organismal process; GO:1902803 regulation of synaptic vesicle transport; GO:0006810 transport; GO:0007267 cell-cell signaling; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:0023058 adaptation of signaling pathway; GO:0044260 cellular macromolecule metabolic process; GO:0044708 single-organism behavior; GO:0051640 organelle localization; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0044707 single-multicellular organism process; GO:0090148 membrane fission; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0060341 regulation of cellular localization; GO:0051259 protein oligomerization; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:1902578 single-organism localization; GO:0003374 dynamin family protein polymerization involved in mitochondrial fission; GO:0022401 negative adaptation of signaling pathway; GO:1902580 single-organism cellular localization; GO:0006898 receptor-mediated endocytosis; GO:0030534 adult behavior; GO:0009966 regulation of signal transduction; GO:0006461 protein complex assembly; GO:0036465 synaptic vesicle recycling; GO:0016192 vesicle-mediated transport; GO:0051932 synaptic transmission, GABAergic; GO:0051656 establishment of organelle localization; GO:0097480 establishment of synaptic vesicle localization; GO:0099536 synaptic signaling; GO:0097479 synaptic vesicle localization; GO:0006996 organelle organization; GO:0006900 membrane budding; GO:0061024 membrane organization; GO:0007605 sensory perception of sound; GO:0007268 chemical synaptic transmission; GO:0051179 localization; GO:0010256 endomembrane system organization; GO:0031623 receptor internalization; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:1901998 toxin transport; GO:0099504 synaptic vesicle cycle; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0051262 protein tetramerization; GO:0007005 mitochondrion organization; GO:0098916 anterograde trans-synaptic signaling; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0051650 establishment of vesicle localization; GO:0007600 sensory perception; GO:0071822 protein complex subunit organization; GO:0043112 receptor metabolic process; GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane; GO:0008277 regulation of G-protein coupled receptor protein signaling pathway; GO:0032386 regulation of intracellular transport; GO:0023052 signaling; GO:1902582 single-organism intracellular transport; GO:0051050 positive regulation of transport; GO:0050789 regulation of biological process; GO:0051258 protein polymerization; GO:0070271 protein complex biogenesis; GO:0050954 sensory perception of mechanical stimulus; GO:0016043 cellular component organization; GO:0008344 adult locomotory behavior; GO:0048285 organelle fission; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0072583 clathrin-dependent endocytosis; GO:0003373 dynamin family protein polymerization involved in membrane fission; GO:0048013 ephrin receptor signaling pathway; GO:0051648 vesicle localization; GO:0002029 desensitization of G-protein coupled receptor protein signaling pathway; GO:0099537 trans-synaptic signaling; GO:0009987 cellular process; GO:0043623 cellular protein complex assembly; GO:0034622 cellular macromolecular complex assembly; GO:0003008 system process; GO:0032388 positive regulation of intracellular transport; GO:0051049 regulation of transport; GO:0044802 single-organism membrane organization; GO:0016050 vesicle organization; GO:0048585 negative regulation of response to stimulus; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0043933 macromolecular complex subunit organization; GO:0051641 cellular localization; GO:0000266 mitochondrial fission; GO:0070142 synaptic vesicle budding; GO:0048488 synaptic vesicle endocytosis; GO:0007626 locomotory behavior; GO:0002031 G-protein coupled receptor internalization; GO:0007032 endosome organization; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0043196 varicosity; GO:0005623 cell; GO:0099080 supramolecular complex; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070382 exocytic vesicle; GO:0070062 extracellular exosome; GO:0001917 photoreceptor inner segment; GO:0008021 synaptic vesicle; GO:0043209 myelin sheath; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0099513 polymeric cytoskeletal fiber; GO:0042995 cell projection; GO:0044430 cytoskeletal part; GO:0048475 coated membrane; GO:0031967 organelle envelope; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0033267 axon part; GO:0005886 plasma membrane; GO:0099081 supramolecular polymer; GO:0043231 intracellular membrane-bounded organelle; GO:0030424 axon; GO:0031975 envelope; GO:0030117 membrane coat; GO:0043234 protein complex; GO:0030133 transport vesicle; GO:0031966 mitochondrial membrane; GO:0043230 extracellular organelle; GO:0005874 microtubule; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0099512 supramolecular fiber; GO:0005856 cytoskeleton; GO:0005740 mitochondrial envelope; GO:0015630 microtubule cytoskeleton; GO:0044464 cell part; GO:0044304 main axon; GO:0098793 presynapse; GO:0044425 membrane part; GO:1903561 extracellular vesicle; GO:0044456 synapse part; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0044429 mitochondrial part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044463 cell projection part; GO:0045202 synapse; GO:0043226 organelle; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0005102 receptor binding; GO:0019901 protein kinase binding; GO:0046983 protein dimerization activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0050998 nitric-oxide synthase binding; GO:0016787 hydrolase activity; GO:0031749 D2 dopamine receptor binding; GO:0005515 protein binding; GO:0050780 dopamine receptor binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0008092 cytoskeletal protein binding; GO:0042802 identical protein binding; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0008017 microtubule binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0003924 GTPase activity; GO:0043168 anion binding; GO:0008022 protein C-terminus binding; GO:0001664 G-protein coupled receptor binding; GO:0019001 guanyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003723 RNA binding; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0015631 tubulin binding; GO:0000166 nucleotide binding; GO:0019900 kinase binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003676 nucleic acid binding; GO:0032555 purine ribonucleotide binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019899 enzyme binding; GO:0032403 protein complex binding; GO:0036094 small molecule binding; ","K01528","DNM; dynamin GTPase [EC:3.6.5.5]","hsa05100 Bacterial invasion of epithelial cells - Homo sapiens (human); hsa04666 Fc gamma R-mediated phagocytosis - Homo sapiens (human); hsa04072 Phospholipase D signaling pathway - Homo sapiens (human); hsa04144 Endocytosis - Homo sapiens (human); hsa04961 Endocrine and other factor-regulated calcium reabsorption - Homo sapiens (human); hsa04721 Synaptic vesicle cycle - Homo sapiens (human); ","IPR030381; IPR003130; IPR001401; IPR027417; IPR020850; IPR001849; IPR011993; IPR000375; ","\"Dynamin-type guanine nucleotide-binding (G) domain; Dynamin GTPase effector; Dynamin, GTPase domain; P-loop containing nucleoside triphosphate hydrolase; GTPase effector domain; Pleckstrin homology domain; PH domain-like; Dynamin central domain; \"\r"]
["Q05469","Hormone-sensitive lipase OS=Homo sapiens OX=9606 GN=LIPE","LIPE",116.6,24.662,6.3,6,9,6,1.072,1.144,1.168,0.962,0.871,0.811,0.781,0.0112,"nucleus\r","GO:0016310 phosphorylation; GO:0046486 glycerolipid metabolic process; GO:1901615 organic hydroxy compound metabolic process; GO:1902652 secondary alcohol metabolic process; GO:0006066 alcohol metabolic process; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0016125 sterol metabolic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0046464 acylglycerol catabolic process; GO:0071704 organic substance metabolic process; GO:0046461 neutral lipid catabolic process; GO:0008152 metabolic process; GO:0006468 protein phosphorylation; GO:0042758 long-chain fatty acid catabolic process; GO:0006639 acylglycerol metabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0044248 cellular catabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009987 cellular process; GO:0006629 lipid metabolic process; GO:0019433 triglyceride catabolic process; GO:0016042 lipid catabolic process; GO:0006638 neutral lipid metabolic process; GO:0008203 cholesterol metabolic process; GO:0044712 single-organism catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0008202 steroid metabolic process; GO:0072329 monocarboxylic acid catabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0044282 small molecule catabolic process; GO:0006631 fatty acid metabolic process; GO:0044238 primary metabolic process; GO:0046395 carboxylic acid catabolic process; GO:1901575 organic substance catabolic process; GO:0006641 triglyceride metabolic process; GO:0046340 diacylglycerol catabolic process; GO:0006793 phosphorus metabolic process; GO:0001676 long-chain fatty acid metabolic process; GO:0044710 single-organism metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0016054 organic acid catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0044242 cellular lipid catabolic process; GO:0006464 cellular protein modification process; GO:0006082 organic acid metabolic process; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:0009062 fatty acid catabolic process; GO:0009056 catabolic process; GO:0043436 oxoacid metabolic process; GO:0046339 diacylglycerol metabolic process; GO:0046503 glycerolipid catabolic process; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0043232 intracellular non-membrane-bounded organelle; GO:0098857 membrane microdomain; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0005901 caveola; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005886 plasma membrane; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0098590 plasma membrane region; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0044853 plasma membrane raft; GO:0098805 whole membrane; GO:0098589 membrane region; GO:0045121 membrane raft; GO:0005811 lipid particle; GO:0044444 cytoplasmic part; ","GO:0033878 hormone-sensitive lipase activity; GO:0052689 carboxylic ester hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0019901 protein kinase binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0004806 triglyceride lipase activity; GO:0016298 lipase activity; GO:0019900 kinase binding; GO:0019899 enzyme binding; ","K07188","LIPE; hormone-sensitive lipase [EC:3.1.1.79]","hsa04923 Regulation of lipolysis in adipocytes - Homo sapiens (human); hsa04925 Aldosterone synthesis and secretion - Homo sapiens (human); hsa04024 cAMP signaling pathway - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa04371 Apelin signaling pathway - Homo sapiens (human); hsa04910 Insulin signaling pathway - Homo sapiens (human); hsa04152 AMPK signaling pathway - Homo sapiens (human); ","IPR010468; IPR029058; IPR013094; ","\"Hormone-sensitive lipase, N-terminal; Alpha/Beta hydrolase fold; Alpha/beta hydrolase fold-3; \"\r"]
["Q05707","Collagen alpha-1(XIV) chain OS=Homo sapiens OX=9606 GN=COL14A1","COL14A1",193.51,323.31,36,57,159,57,1.306,1.265,1.302,0.705,0.712,0.702,0.547,3.3e-07,"Golgi apparatus\r","GO:0016043 cellular component organization; GO:0071822 protein complex subunit organization; GO:0030199 collagen fibril organization; GO:0098609 cell-cell adhesion; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0043933 macromolecular complex subunit organization; GO:0022610 biological adhesion; GO:0016337 single organismal cell-cell adhesion; GO:0043062 extracellular structure organization; GO:0098602 single organism cell adhesion; GO:0007155 cell adhesion; GO:0030198 extracellular matrix organization; GO:0009987 cellular process; GO:0097435 supramolecular fiber organization; GO:0071840 cellular component organization or biogenesis; ","GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005593 FACIT collagen trimer; GO:0005623 cell; GO:0044420 extracellular matrix component; GO:0005581 collagen trimer; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0005596 collagen type XIV trimer; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0030934 anchoring collagen complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005788 endoplasmic reticulum lumen; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031012 extracellular matrix; GO:0044432 endoplasmic reticulum part; GO:0005578 proteinaceous extracellular matrix; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0005201 extracellular matrix structural constituent; GO:0003723 RNA binding; GO:0030674 protein binding, bridging; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0003676 nucleic acid binding; GO:0005518 collagen binding; GO:0060090 binding, bridging; GO:0005515 protein binding; GO:0005198 structural molecule activity; GO:0032403 protein complex binding; ","K08133","COL14A; collagen, type XIV, alpha","hsa04974 Protein digestion and absorption - Homo sapiens (human); ","IPR013783; IPR003961; IPR013320; IPR001791; IPR002035; ","\"Immunoglobulin-like fold; Fibronectin type III; Concanavalin A-like lectin/glucanase domain; Laminin G domain; von Willebrand factor, type A; \"\r"]
["Q06124","Tyrosine-protein phosphatase non-receptor type 11 OS=Homo sapiens OX=9606 GN=PTPN11","PTPN11",68.436,19.354,5.9,3,3,3,0.958,1.13,1.023,1.052,0.866,0.988,0.934,0.408,"cytoplasm\r",{"$cut":{"chars":16606,"head":"GO:0044700 single organism signaling; GO:0002694 regulation of leukocyte activation; GO:0090130 tissue migration; GO:0048008 platelet-derived growth factor receptor signaling pathway; GO:0022414 reproductive process; GO:0050796 regulation of insulin secretion; GO:0042593 glucose homeostasis; GO:0044255 cellular lipid metabolic process; GO:0031347 regulation of defense response; GO:0044237 cellular metabolic process; GO:0051462 regulation of cortisol secretion; GO:0008610 lipid biosynthetic process; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0008152 metabolic process; GO:0006639 acylglycerol metabolic process; GO:0044093 positive regulation of molecular function; GO:0044057 regulation of system process; GO:0046324 regulation of glucose import; GO:0051051 negative regulation of transport; GO:0021587 cerebellum morphogenesis; GO:0042325 regulation of phosphorylation; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0050709 negative regulation of protein secretion; GO:0040014 regulation of multicellular organism growth; GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0030168 platelet activation; GO:0021575 hindbrain morphogenesis; GO:0048699 generation of neurons; GO:1903531 negative regulation of secretion by cell; GO:0044763 single-organism cellular process; GO:0002520 immune system development; GO:0048870 cell motility; GO:2000849 regulation of glucocorticoid secretion; GO:0006935 chemotaxis; GO:0050776 regulation of immune response; GO:0042063 gliogenesis; GO:0045931 positive regulation of mitotic cell cycle; GO:0046825 regulation of protein export from nucleus; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0060123 regulation of growth hormone secretion; GO:0051223 regulation of protein transport; GO:0010171 body morphogenesis; GO:0048609 multicellular organismal reproductive process; GO:0060325 face morphogenesis; GO:0000003 reproduction; GO:0072359 circulatory system development; GO:0044707 single-multicellular organism process; GO:0016310 phosphorylation; GO:0007173 epidermal growth factor receptor signaling pathway; GO:0048519 negative regulation of biological process; GO:2000832 negative regulation of steroid hormone secretion; GO:0035265 organ growth; GO:0009653 anatomical structure morphogenesis; GO:0050867 positive regulation of cell activation; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:0033500 carbohydrate homeostasis; GO:0061458 reproductive system development; GO:0048806 genitalia development; GO:0061582 intestinal epithelial cell migration; GO:0048015 phosphatidylinositol-mediated signaling; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0048878 chemical homeostasis; GO:0030902 hindbrain development; GO:0006638 neutral lipid metabolic process; GO:0045785 positive regulation of cell adhesion; GO:0044711 single-organism biosynthetic process; GO:0006950 response to stress; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0048839 inner ear development; GO:1903039 positive regulation of leukocyte cell-cell adhesion; GO:1901576 organic substance biosynthetic process; GO:0006974 cellular response to DNA damage stimulus; GO:0060348 bone development; GO:0002696 positive regulation of leukocyte activation; GO:0046888 negative regulation of hormone secretion; GO:0031325 positive regulation of cellular metabolic process; GO:0019637 organophosphate metabolic process; GO:0006644 phospholipid metabolic process; GO:0007423 sensory organ development; GO:0043412 macromolecule modification; GO:0048589 developmental growth; GO:0040007 growth; GO:1903827 regulation of cellular protein localization; GO:0048011 neurotrophin TRK receptor signaling pathway; GO:0046486 glycerolipid metabolic process; GO:0051674 localization of cell; GO:2000850 negative regulation of glucocorticoid secret"}},"GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044444 cytoplasmic part; ","GO:0043274 phospholipase binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:1990782 protein tyrosine kinase binding; GO:0005102 receptor binding; GO:0016791 phosphatase activity; GO:0019901 protein kinase binding; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0004721 phosphoprotein phosphatase activity; GO:0051427 hormone receptor binding; GO:0050780 dopamine receptor binding; GO:0005158 insulin receptor binding; GO:0016301 kinase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity; GO:0051428 peptide hormone receptor binding; GO:0001664 G-protein coupled receptor binding; GO:0031748 D1 dopamine receptor binding; GO:0016740 transferase activity; GO:0052742 phosphatidylinositol kinase activity; GO:0030674 protein binding, bridging; GO:0044877 macromolecular complex binding; GO:0004726 non-membrane spanning protein tyrosine phosphatase activity; GO:0019900 kinase binding; GO:0035004 phosphatidylinositol 3-kinase activity; GO:0005070 SH3/SH2 adaptor activity; GO:0050839 cell adhesion molecule binding; GO:0030971 receptor tyrosine kinase binding; GO:0035591 signaling adaptor activity; GO:0004725 protein tyrosine phosphatase activity; GO:0042578 phosphoric ester hydrolase activity; GO:0052813 phosphatidylinositol bisphosphate kinase activity; GO:0016788 hydrolase activity, acting on ester bonds; GO:0019904 protein domain specific binding; GO:0060090 binding, bridging; GO:0016303 1-phosphatidylinositol-3-kinase activity; GO:0043560 insulin receptor substrate binding; GO:0019899 enzyme binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0032403 protein complex binding; ","K07293","PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]","hsa05120 Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human); hsa04920 Adipocytokine signaling pathway - Homo sapiens (human); hsa04072 Phospholipase D signaling pathway - Homo sapiens (human); hsa04650 Natural killer cell mediated cytotoxicity - Homo sapiens (human); hsa04625 C-type lectin receptor signaling pathway - Homo sapiens (human); hsa04722 Neurotrophin signaling pathway - Homo sapiens (human); hsa05168 Herpes simplex infection - Homo sapiens (human); hsa05220 Chronic myeloid leukemia - Homo sapiens (human); hsa04014 Ras signaling pathway - Homo sapiens (human); hsa05211 Renal cell carcinoma - Homo sapiens (human); hsa04670 Leukocyte transendothelial migration - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa04360 Axon guidance - Homo sapiens (human); hsa04931 Insulin resistance - Homo sapiens (human); hsa04630 Jak-STAT signaling pathway - Homo sapiens (human); ","IPR029021; IPR000387; IPR000980; IPR003595; IPR000242; ","\"Protein-tyrosine phosphatase-like; Tyrosine specific protein phosphatases domain; SH2 domain; Protein-tyrosine phosphatase, catalytic; PTP type protein phosphatase; \"\r"]
["Q06210","Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1","GFPT1",78.806,34.217,12,9,11,9,0.964,0.979,0.998,1.062,1.017,0.995,1.045,0.112,"mitochondria\r","GO:0009226 nucleotide-sugar biosynthetic process; GO:0044700 single organism signaling; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0006002 fructose 6-phosphate metabolic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0030968 endoplasmic reticulum unfolded protein response; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0035966 response to topologically incorrect protein; GO:0006520 cellular amino acid metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0006091 generation of precursor metabolites and energy; GO:0007154 cell communication; GO:0070887 cellular response to chemical stimulus; GO:0010468 regulation of gene expression; GO:0006047 UDP-N-acetylglucosamine metabolic process; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0006048 UDP-N-acetylglucosamine biosynthetic process; GO:0005975 carbohydrate metabolic process; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0007623 circadian rhythm; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0019222 regulation of metabolic process; GO:0006082 organic acid metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0043436 oxoacid metabolic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0033554 cellular response to stress; GO:0035967 cellular response to topologically incorrect protein; GO:0034976 response to endoplasmic reticulum stress; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0006541 glutamine metabolic process; GO:0036498 IRE1-mediated unfolded protein response; GO:0006112 energy reserve metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009987 cellular process; GO:0009064 glutamine family amino acid metabolic process; GO:0006986 response to unfolded protein; GO:0006950 response to stress; GO:0034620 cellular response to unfolded protein; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901605 alpha-amino acid metabolic process; GO:0032922 circadian regulation of gene expression; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0048511 rhythmic process; GO:0019752 carboxylic acid metabolic process; GO:0019637 organophosphate metabolic process; GO:0006040 amino sugar metabolic process; GO:0009225 nucleotide-sugar metabolic process; GO:0046349 amino sugar biosynthetic process; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016769 transferase activity, transferring nitrogenous groups; GO:0097367 carbohydrate derivative binding; GO:0070548 L-glutamine aminotransferase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0030246 carbohydrate binding; GO:0008483 transaminase activity; GO:0016740 transferase activity; GO:0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity; ","K00820","glmS; glucosamine---fructose-6-phosphate aminotransferase (isomerizing) [EC:2.6.1.16]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00250 Alanine, aspartate and glutamate metabolism - Homo sapiens (human); hsa00520 Amino sugar and nucleotide sugar metabolism - Homo sapiens (human); hsa04931 Insulin resistance - Homo sapiens (human); ","IPR029055; IPR001347; IPR017932; ","\"Nucleophile aminohydrolases, N-terminal; Sugar isomerase (SIS); Glutamine amidotransferase type 2 domain; \"\r"]
["Q06546","GA-binding protein alpha chain OS=Homo sapiens OX=9606 GN=GABPA","GABPA",51.295,2.5227,2,1,1,1,1.111,0.929,1.035,1.02,0.956,0.962,0.955,0.482,"nucleus\r","GO:0051093 negative regulation of developmental process; GO:0097659 nucleic acid-templated transcription; GO:0043009 chordate embryonic development; GO:0048869 cellular developmental process; GO:0045637 regulation of myeloid cell differentiation; GO:0009891 positive regulation of biosynthetic process; GO:0044699 single-organism process; GO:0051241 negative regulation of multicellular organismal process; GO:0009058 biosynthetic process; GO:0045653 negative regulation of megakaryocyte differentiation; GO:0044237 cellular metabolic process; GO:0051253 negative regulation of RNA metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0007005 mitochondrion organization; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0043170 macromolecule metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0009790 embryo development; GO:0045596 negative regulation of cell differentiation; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0045638 negative regulation of myeloid cell differentiation; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044763 single-organism cellular process; GO:0000122 negative regulation of transcription from RNA polymerase II promoter; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0016070 RNA metabolic process; GO:0002683 negative regulation of immune system process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0001701 in utero embryonic development; GO:0045652 regulation of megakaryocyte differentiation; GO:1902679 negative regulation of RNA biosynthetic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0002682 regulation of immune system process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0048856 anatomical structure development; GO:1901362 organic cyclic compound biosynthetic process; GO:2000026 regulation of multicellular organismal development; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0051239 regulation of multicellular organismal process; GO:0071704 organic substance metabolic process; GO:1903706 regulation of hemopoiesis; GO:0045892 negative regulation of transcription, DNA-templated; GO:0030154 cell differentiation; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0034641 cellular nitrogen compound metabolic process; GO:1903707 negative regulation of hemopoiesis; GO:0007275 multicellular organism development; GO:0009059 macromolecule biosynthetic process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0051254 positive regulation of RNA metabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0009792 embryo development ending in birth or egg hatching; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0009890 negative regulation of biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0031325 positive regulation of cellular metabolic process; GO:0006366 transcription from RNA polymerase II promoter; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0010467 gene expression; GO:0031327 negative regulation of cellular biosynthetic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0050793 regulation of developmental process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031974 membrane-enclosed lumen; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0000785 chromatin; GO:0044454 nuclear chromosome part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0000790 nuclear chromatin; GO:0000228 nuclear chromosome; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding; GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding; GO:0003677 DNA binding; GO:0046982 protein heterodimerization activity; GO:0000976 transcription regulatory region sequence-specific DNA binding; GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding; GO:0003690 double-stranded DNA binding; GO:1990837 sequence-specific double-stranded DNA binding; GO:0001012 RNA polymerase II regulatory region DNA binding; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:0003682 chromatin binding; GO:0003712 transcription cofactor activity; GO:0043565 sequence-specific DNA binding; GO:0000987 core promoter proximal region sequence-specific DNA binding; GO:0003700 transcription factor activity, sequence-specific DNA binding; GO:0000975 regulatory region DNA binding; GO:0001159 core promoter proximal region DNA binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding; GO:0001067 regulatory region nucleic acid binding; GO:0044212 transcription regulatory region DNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0001071 nucleic acid binding transcription factor activity; GO:0000989 transcription factor activity, transcription factor binding; GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding; GO:0003713 transcription coactivator activity; GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding; GO:0000988 transcription factor activity, protein binding; ","K09441",null,null,"IPR011991; IPR003118; IPR013761; IPR000418; IPR029071; IPR024668; ","\"Winged helix-turn-helix DNA-binding domain; Pointed domain; Sterile alpha motif/pointed domain; Ets domain; Ubiquitin-related domain; GA-binding protein alpha subunit, N-terminal; \"\r"]
["Q07020","60S ribosomal protein L18 OS=Homo sapiens OX=9606 GN=RPL18","RPL18",21.634,69.057,34.6,6,16,6,0.895,0.89,0.886,1.077,1.08,1.099,1.219,4.57e-06,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0072594 establishment of protein localization to organelle; GO:0006518 peptide metabolic process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0051649 establishment of localization in cell; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0070972 protein localization to endoplasmic reticulum; GO:0006364 rRNA processing; GO:0006413 translational initiation; GO:1901361 organic cyclic compound catabolic process; GO:0033365 protein localization to organelle; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0006412 translation; GO:0016072 rRNA metabolic process; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0072657 protein localization to membrane; GO:0043043 peptide biosynthetic process; GO:0042254 ribosome biogenesis; GO:1901360 organic cyclic compound metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032774 RNA biosynthetic process; GO:0045047 protein targeting to ER; GO:0043603 cellular amide metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0006401 RNA catabolic process; GO:0016070 RNA metabolic process; GO:0019439 aromatic compound catabolic process; GO:1901575 organic substance catabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0019083 viral transcription; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0046907 intracellular transport; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0044267 cellular protein metabolic process; GO:0006613 cotranslational protein targeting to membrane; GO:0048519 negative regulation of biological process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0016032 viral process; GO:0019080 viral gene expression; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0006886 intracellular protein transport; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0034613 cellular protein localization; GO:0009059 macromolecule biosynthetic process; GO:0090150 establishment of protein localization to membrane; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0051179 localization; GO:0009056 catabolic process; GO:0034660 ncRNA metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005925 focal adhesion; GO:0070013 intracellular organelle lumen; GO:0044391 ribosomal subunit; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:0030055 cell-substrate junction; GO:0044445 cytosolic part; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0022626 cytosolic ribosome; GO:0043229 intracellular organelle; GO:0005840 ribosome; GO:0043232 intracellular non-membrane-bounded organelle; GO:0022625 cytosolic large ribosomal subunit; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0015934 large ribosomal subunit; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005198 structural molecule activity; GO:0003735 structural constituent of ribosome; ","K02883","RP-L18e; large subunit ribosomal protein L18e","hsa03010 Ribosome - Homo sapiens (human); ","IPR021131; ","Ribosomal protein L18e/L15P; \r"]
["Q07065","Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4","CKAP4",66.022,323.31,57.6,32,49,32,1.072,1.044,1.086,0.938,0.939,0.914,0.872,0.000704,"plasma membrane\r","GO:0045321 leukocyte activation; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0036230 granulocyte activation; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0009987 cellular process; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0002443 leukocyte mediated immunity; GO:0016192 vesicle-mediated transport; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:0043312 neutrophil degranulation; GO:0002263 cell activation involved in immune response; GO:0002444 myeloid leukocyte mediated immunity; GO:0002366 leukocyte activation involved in immune response; GO:0006810 transport; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:0032940 secretion by cell; GO:0044260 cellular macromolecule metabolic process; GO:0001775 cell activation; GO:0043299 leukocyte degranulation; GO:0051179 localization; GO:0006955 immune response; GO:0006887 exocytosis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005765 lysosomal membrane; GO:0005654 nucleoplasm; GO:0016607 nuclear speck; GO:0005622 intracellular; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0035577 azurophil granule membrane; GO:0031981 nuclear lumen; GO:0012506 vesicle membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0042582 azurophil granule; GO:0031012 extracellular matrix; GO:0043231 intracellular membrane-bounded organelle; GO:0030667 secretory granule membrane; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043230 extracellular organelle; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0000932 P-body; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0042599 lamellar body; GO:0016604 nuclear body; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0005856 cytoskeleton; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0030141 secretory granule; GO:0005811 lipid particle; GO:0035579 specific granule membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0016021 integral component of membrane; GO:0098852 lytic vacuole membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0005634 nucleus; GO:0044432 endoplasmic reticulum part; GO:0042581 specific granule; GO:0035770 ribonucleoprotein granule; GO:0005774 vacuolar membrane; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; ","K13999","CKAP4; cytoskeleton-associated protein 4","hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); "]
["Q07075","Glutamyl aminopeptidase OS=Homo sapiens OX=9606 GN=ENPEP","ENPEP",109.24,12.53,3.7,3,3,3,0.973,1.068,1.037,0.915,1.025,0.991,0.952,0.32,"extracellular\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0007586 digestion; GO:0006518 peptide metabolic process; GO:0051674 localization of cell; GO:0001568 blood vessel development; GO:0044236 multicellular organism metabolic process; GO:0016486 peptide hormone processing; GO:0044699 single-organism process; GO:0016485 protein processing; GO:0060177 regulation of angiotensin metabolic process; GO:0044237 cellular metabolic process; GO:0002005 angiotensin catabolic process in blood; GO:0001525 angiogenesis; GO:0008152 metabolic process; GO:0007154 cell communication; GO:0043171 peptide catabolic process; GO:0003073 regulation of systemic arterial blood pressure; GO:0048514 blood vessel morphogenesis; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044259 multicellular organismal macromolecule metabolic process; GO:0032502 developmental process; GO:0003044 regulation of systemic arterial blood pressure mediated by a chemical signal; GO:0042445 hormone metabolic process; GO:0001990 regulation of systemic arterial blood pressure by hormone; GO:0080090 regulation of primary metabolic process; GO:0044256 protein digestion; GO:0050886 endocrine process; GO:0044763 single-organism cellular process; GO:0001944 vasculature development; GO:0002003 angiotensin maturation; GO:0043603 cellular amide metabolic process; GO:0048870 cell motility; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:1901575 organic substance catabolic process; GO:0048513 animal organ development; GO:0001655 urogenital system development; GO:0050789 regulation of biological process; GO:0007267 cell-cell signaling; GO:0044710 single-organism metabolic process; GO:0030163 protein catabolic process; GO:0019222 regulation of metabolic process; GO:0010817 regulation of hormone levels; GO:0040011 locomotion; GO:0003013 circulatory system process; GO:0048856 anatomical structure development; GO:0044266 multicellular organismal macromolecule catabolic process; GO:0072359 circulatory system development; GO:0008217 regulation of blood pressure; GO:0016477 cell migration; GO:0044707 single-multicellular organism process; GO:0044268 multicellular organismal protein metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0072001 renal system development; GO:0071704 organic substance metabolic process; GO:0032835 glomerulus development; GO:0009653 anatomical structure morphogenesis; GO:0044243 multicellular organismal catabolic process; GO:0002002 regulation of angiotensin levels in blood; GO:0008015 blood circulation; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0006508 proteolysis; GO:0072006 nephron development; GO:0007275 multicellular organism development; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0009987 cellular process; GO:0044254 multicellular organismal protein catabolic process; GO:0001991 regulation of systemic arterial blood pressure by circulatory renin-angiotensin; GO:0001822 kidney development; GO:0003008 system process; GO:0044712 single-organism catabolic process; GO:0048731 system development; GO:0006807 nitrogen compound metabolic process; GO:0072358 cardiovascular system development; GO:0008283 cell proliferation; GO:0044238 primary metabolic process; GO:1901565 organonitrogen compound catabolic process; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0009057 macromolecule catabolic process; GO:0006928 movement of cell or subcellular component; GO:0010467 gene expression; GO:0051179 localization; GO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin; GO:0051604 protein maturation; GO:0009056 catabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0098862 cluster of actin-based cell projections; GO:0005903 brush border; GO:0009897 external side of plasma membrane; GO:0016324 apical plasma membrane; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0005765 lysosomal membrane; GO:0070062 extracellular exosome; GO:0098590 plasma membrane region; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0045177 apical part of cell; GO:0000323 lytic vacuole; GO:0098552 side of membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0031226 intrinsic component of plasma membrane; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0098852 lytic vacuole membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0009986 cell surface; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0008238 exopeptidase activity; GO:0008233 peptidase activity; GO:0043167 ion binding; GO:0070006 metalloaminopeptidase activity; GO:0008235 metalloexopeptidase activity; GO:0004177 aminopeptidase activity; GO:0016787 hydrolase activity; GO:0008237 metallopeptidase activity; GO:0033218 amide binding; GO:0008270 zinc ion binding; GO:0046914 transition metal ion binding; GO:0042277 peptide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0046872 metal ion binding; GO:0043169 cation binding; ","K11141","ENPEP; glutamyl aminopeptidase [EC:3.4.11.7]","hsa04614 Renin-angiotensin system - Homo sapiens (human); ","IPR014782; IPR024571; ","\"Peptidase M1, membrane alanine aminopeptidase, N-terminal; ERAP1-like C-terminal domain; \"\r"]
["Q07666","KH domain-containing, RNA-binding, signal transduction-associated protein 1 OS=Homo sapiens OX=9606 GN=KHDRBS1","KHDRBS1",48.227,56.744,17.6,8,13,8,0.917,0.943,0.943,1.117,1.083,1.02,1.149,0.00812,"cytoplasm\r","GO:0044700 single organism signaling; GO:0032270 positive regulation of cellular protein metabolic process; GO:0007166 cell surface receptor signaling pathway; GO:0097659 nucleic acid-templated transcription; GO:0010608 posttranscriptional regulation of gene expression; GO:0009891 positive regulation of biosynthetic process; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0032879 regulation of localization; GO:0044770 cell cycle phase transition; GO:0043170 macromolecule metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0006396 RNA processing; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0050684 regulation of mRNA processing; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0000086 G2/M transition of mitotic cell cycle; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0032239 regulation of nucleobase-containing compound transport; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0060341 regulation of cellular localization; GO:0045892 negative regulation of transcription, DNA-templated; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0051171 regulation of nitrogen compound metabolic process; GO:0009966 regulation of signal transduction; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0044772 mitotic cell cycle phase transition; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0008283 cell proliferation; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0034248 regulation of cellular amide metabolic process; GO:0043484 regulation of RNA splicing; GO:1903311 regulation of mRNA metabolic process; GO:0009890 negative regulation of biosynthetic process; GO:0046833 positive regulation of RNA export from nucleus; GO:0051247 positive regulation of protein metabolic process; GO:0046822 regulation of nucleocytoplasmic transport; GO:0031325 positive regulation of cellular metabolic process; GO:0044839 cell cycle G2/M phase transition; GO:0048584 positive regulation of response to stimulus; GO:0031328 positive regulation of cellular biosynthetic process; GO:0046831 regulation of RNA export from nucleus; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0051253 negative regulation of RNA metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0046824 positive regulation of nucleocytoplasmic transport; GO:0051726 regulation of cell cycle; GO:0048024 regulation of mRNA splicing, via spliceosome; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0045727 positive regulation of translation; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0032386 regulation of intracellular transport; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051050 positive regulation of transport; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:1902679 negative regulation of RNA biosynthetic process; GO:0019222 regulation of metabolic process; GO:0045786 negative regulation of cell cycle; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0032241 positive regulation of nucleobase-containing compound transport; GO:0023056 positive regulation of signaling; GO:0034641 cellular nitrogen compound metabolic process; GO:0010647 positive regulation of cell communication; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0007050 cell cycle arrest; GO:0045948 positive regulation of translational initiation; GO:0051049 regulation of transport; GO:0032388 positive regulation of intracellular transport; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0006417 regulation of translation; GO:0051246 regulation of protein metabolic process; GO:0006446 regulation of translational initiation; GO:0034250 positive regulation of cellular amide metabolic process; GO:0010467 gene expression; GO:0022402 cell cycle process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0009967 positive regulation of signal transduction; GO:0007049 cell cycle; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0098797 plasma membrane protein complex; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0044422 organelle part; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0070013 intracellular organelle lumen; GO:0070618 Grb2-Sos complex; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0008143 poly(A) binding; GO:0003677 DNA binding; GO:0003723 RNA binding; GO:0030674 protein binding, bridging; GO:0044877 macromolecular complex binding; GO:0005515 protein binding; GO:0070717 poly-purine tract binding; GO:0017124 SH3 domain binding; GO:0003727 single-stranded RNA binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0005070 SH3/SH2 adaptor activity; GO:0008187 poly-pyrimidine tract binding; GO:0042802 identical protein binding; GO:0035591 signaling adaptor activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0019904 protein domain specific binding; GO:0060090 binding, bridging; GO:0008266 poly(U) RNA binding; GO:0032403 protein complex binding; ","K13198",null,null,"IPR004087; IPR004088; IPR032571; IPR032335; ","\"K Homology domain; K Homology domain, type 1; KHDRBS, Qua1 domain; Sam68, tyrosine-rich domain; \"\r"]
["Q07812","Apoptosis regulator BAX OS=Homo sapiens OX=9606 GN=BAX","BAX",21.184,13.554,18.8,3,4,3,1.011,0.949,1.018,0.998,0.998,1.033,1.017,0.528,"plasma membrane\r",{"$cut":{"chars":28724,"head":"GO:0044700 single organism signaling; GO:0022414 reproductive process; GO:0044255 cellular lipid metabolic process; GO:0032091 negative regulation of protein binding; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0072431 signal transduction involved in mitotic G1 DNA damage checkpoint; GO:0042110 T cell activation; GO:0055065 metal ion homeostasis; GO:0009790 embryo development; GO:0002339 B cell selection; GO:0048598 embryonic morphogenesis; GO:1905898 positive regulation of response to endoplasmic reticulum stress; GO:0010248 establishment or maintenance of transmembrane electrochemical gradient; GO:0052548 regulation of endopeptidase activity; GO:0001777 T cell homeostatic proliferation; GO:0051054 positive regulation of DNA metabolic process; GO:0080090 regulation of primary metabolic process; GO:0048592 eye morphogenesis; GO:1902110 positive regulation of mitochondrial membrane permeability involved in apoptotic process; GO:2000134 negative regulation of G1/S transition of mitotic cell cycle; GO:0048870 cell motility; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0006810 transport; GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:1902400 intracellular signal transduction involved in G1 DNA damage checkpoint; GO:1904748 regulation of apoptotic process involved in development; GO:0032976 release of matrix enzymes from mitochondria; GO:0072655 establishment of protein localization to mitochondrion; GO:0060548 negative regulation of cell death; GO:0072359 circulatory system development; GO:2001239 regulation of extrinsic apoptotic signaling pathway in absence of ligand; GO:0044707 single-multicellular organism process; GO:2001056 positive regulation of cysteine-type endopeptidase activity; GO:0070230 positive regulation of lymphocyte apoptotic process; GO:0009653 anatomical structure morphogenesis; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0045136 development of secondary sexual characteristics; GO:1902402 signal transduction involved in mitotic DNA damage checkpoint; GO:0044819 mitotic G1/S transition checkpoint; GO:0009896 positive regulation of catabolic process; GO:0010959 regulation of metal ion transport; GO:0042100 B cell proliferation; GO:0048806 genitalia development; GO:0061458 reproductive system development; GO:0048878 chemical homeostasis; GO:0051928 positive regulation of calcium ion transport; GO:0001822 kidney development; GO:0051282 regulation of sequestering of calcium ion; GO:0033599 regulation of mammary gland epithelial cell proliferation; GO:0009416 response to light stimulus; GO:0042733 embryonic digit morphogenesis; GO:0072331 signal transduction by p53 class mediator; GO:1902510 regulation of apoptotic DNA fragmentation; GO:0008283 cell proliferation; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0043496 regulation of protein homodimerization activity; GO:0006974 cellular response to DNA damage stimulus; GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage; GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process; GO:0030326 embryonic limb morphogenesis; GO:1902742 apoptotic process involved in development; GO:0048515 spermatid differentiation; GO:1903519 regulation of mammary gland involution; GO:2000045 regulation of G1/S transition of mitotic cell cycle; GO:0072594 establishment of protein localization to organelle; GO:0060561 apoptotic process involved in morphogenesis; GO:0001568 blood vessel development; GO:0031331 positive regulation of cellular catabolic process; GO:0048869 cellular developmental process; GO:0009611 response to wounding; GO:0045930 negative regulation of mitotic cell cycle; GO:0007165 signal transduction; GO:0000077 DNA damage checkpoint; GO:0032990 cell part morphogenesis; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:1902806 regulation of cell cycle G1/S phase transition; GO:00066"}},"GO:0016020 membrane; GO:0097136 Bcl-2 family protein complex; GO:0005783 endoplasmic reticulum; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0019867 outer membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0032991 macromolecular complex; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0031968 organelle outer membrane; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0044429 mitochondrial part; GO:0005635 nuclear envelope; GO:0046930 pore complex; GO:0005741 mitochondrial outer membrane; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0097144 BAX complex; GO:0005829 cytosol; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0044432 endoplasmic reticulum part; GO:0031975 envelope; GO:0005757 mitochondrial permeability transition pore complex; GO:0043234 protein complex; GO:0031966 mitochondrial membrane; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0051434 BH3 domain binding; GO:0031072 heat shock protein binding; GO:0046982 protein heterodimerization activity; GO:0051087 chaperone binding; GO:0046983 protein dimerization activity; GO:0022803 passive transmembrane transporter activity; GO:0005515 protein binding; GO:0030544 Hsp70 protein binding; GO:0015267 channel activity; GO:0070513 death domain binding; GO:0042802 identical protein binding; GO:0051400 BH domain binding; GO:0005488 binding; GO:0042803 protein homodimerization activity; GO:0008289 lipid binding; GO:0019904 protein domain specific binding; GO:0022857 transmembrane transporter activity; GO:0005215 transporter activity; ","K02159","BAX; apoptosis regulator BAX","hsa05152 Tuberculosis - Homo sapiens (human); hsa05220 Chronic myeloid leukemia - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa05222 Small cell lung cancer - Homo sapiens (human); hsa05166 HTLV-I infection - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa04071 Sphingolipid signaling pathway - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa05213 Endometrial cancer - Homo sapiens (human); hsa04933 AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human); hsa05014 Amyotrophic lateral sclerosis (ALS) - Homo sapiens (human); hsa04211 Longevity regulating pathway - Homo sapiens (human); hsa05224 Breast cancer - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa01522 Endocrine resistance - Homo sapiens (human); hsa05161 Hepatitis B - Homo sapiens (human); hsa04215 Apoptosis - multiple species - Homo sapiens (human); hsa01521 EGFR tyrosine kinase inhibitor resistance - Homo sapiens (human); hsa05210 Colorectal cancer - Homo sapiens (human); hsa05216 Thyroid cancer - Homo sapiens (human); hsa04210 Apoptosis - Homo sapiens (human); hsa04722 Neurotrophin signaling pathway - Homo sapiens (human); hsa04217 Necroptosis - Homo sapiens (human); hsa04115 p53 signaling pathway - Homo sapiens (human); hsa05167 Kaposi's sarcoma-associated herpesvirus infection - Homo sapiens (human); hsa05225 Hepatocellular carcinoma - Homo sapiens (human); hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human); hsa01524 Platinum drug resistance - Homo sapiens (human); hsa05223 Non-small cell lung cancer - Homo sapiens (human); hsa05020 Prion diseases - Homo sapiens (human); hsa05203 Viral carcinogenesis - Homo sapiens (human); hsa05214 Glioma - Homo sapiens (human); hsa05226 Gastric cancer - Homo sapiens (human); hsa05217 Basal cell carcinoma - Homo sapiens (human); hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); hsa05212 Pancreatic cancer - Homo sapiens (human); hsa05218 Melanoma - Homo sapiens (human); "]
["Q07954","Prolow-density lipoprotein receptor-related protein 1 OS=Homo sapiens OX=9606 GN=LRP1","LRP1",504.6,323.31,15.1,60,91,60,1.149,1.158,1.157,0.862,0.867,0.851,0.745,5.26e-07,"plasma membrane\r","GO:0044700 single organism signaling; GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway; GO:0010941 regulation of cell death; GO:0032371 regulation of sterol transport; GO:0007420 brain development; GO:0043523 regulation of neuron apoptotic process; GO:0044255 cellular lipid metabolic process; GO:0021987 cerebral cortex development; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0042157 lipoprotein metabolic process; GO:0021537 telencephalon development; GO:0008152 metabolic process; GO:0032879 regulation of localization; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0051493 regulation of cytoskeleton organization; GO:0008104 protein localization; GO:0044765 single-organism transport; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0048699 generation of neurons; GO:0060191 regulation of lipase activity; GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway; GO:0044763 single-organism cellular process; GO:2000146 negative regulation of cell motility; GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway; GO:0032501 multicellular organismal process; GO:0050768 negative regulation of neurogenesis; GO:0006810 transport; GO:0048513 animal organ development; GO:0051336 regulation of hydrolase activity; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0007417 central nervous system development; GO:0048583 regulation of response to stimulus; GO:0045665 negative regulation of neuron differentiation; GO:0051223 regulation of protein transport; GO:0014912 negative regulation of smooth muscle cell migration; GO:0048844 artery morphogenesis; GO:0016101 diterpenoid metabolic process; GO:0010721 negative regulation of cell development; GO:0060548 negative regulation of cell death; GO:0010975 regulation of neuron projection development; GO:0072359 circulatory system development; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0032956 regulation of actin cytoskeleton organization; GO:0043067 regulation of programmed cell death; GO:0010517 regulation of phospholipase activity; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0051239 regulation of multicellular organismal process; GO:0009653 anatomical structure morphogenesis; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0043524 negative regulation of neuron apoptotic process; GO:0010715 regulation of extracellular matrix disassembly; GO:1902578 single-organism localization; GO:2000145 regulation of cell motility; GO:0031345 negative regulation of cell projection organization; GO:0030900 forebrain development; GO:0032880 regulation of protein localization; GO:0006898 receptor-mediated endocytosis; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:1901215 negative regulation of neuron death; GO:0006720 isoprenoid metabolic process; GO:0097242 beta-amyloid clearance; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0035909 aorta morphogenesis; GO:0016192 vesicle-mediated transport; GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway; GO:0030334 regulation of cell migration; GO:0071702 organic substance transport; GO:0010977 negative regulation of neuron projection development; GO:0008283 cell proliferation; GO:0072358 cardiovascular system development; GO:0032970 regulation of actin filament-based process; GO:0044238 primary metabolic process; GO:0045184 establishment of protein localization; GO:0010874 regulation of cholesterol efflux; GO:0007186 G-protein coupled receptor signaling pathway; GO:1904951 positive regulation of establishment of protein localization; GO:0030336 negative regulation of cell migration; GO:0030111 regulation of Wnt signaling pathway; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0051093 negative regulation of developmental process; GO:0009968 negative regulation of signal transduction; GO:0001568 blood vessel development; GO:0023051 regulation of signaling; GO:0051129 negative regulation of cellular component organization; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0051241 negative regulation of multicellular organismal process; GO:0022008 neurogenesis; GO:0051234 establishment of localization; GO:0006909 phagocytosis; GO:0040013 negative regulation of locomotion; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0044872 lipoprotein localization; GO:0007154 cell communication; GO:0032376 positive regulation of cholesterol transport; GO:0060322 head development; GO:0048514 blood vessel morphogenesis; GO:0033036 macromolecule localization; GO:2000586 regulation of platelet-derived growth factor receptor-beta signaling pathway; GO:0045596 negative regulation of cell differentiation; GO:0006629 lipid metabolic process; GO:0032502 developmental process; GO:0030178 negative regulation of Wnt signaling pathway; GO:0001944 vasculature development; GO:0023052 signaling; GO:0032374 regulation of cholesterol transport; GO:0035904 aorta development; GO:0051050 positive regulation of transport; GO:0050789 regulation of biological process; GO:0045664 regulation of neuron differentiation; GO:0060840 artery development; GO:0007568 aging; GO:0065009 regulation of molecular function; GO:0048856 anatomical structure development; GO:0051222 positive regulation of protein transport; GO:0051271 negative regulation of cellular component movement; GO:2000026 regulation of multicellular organismal development; GO:0021543 pallium development; GO:0043069 negative regulation of programmed cell death; GO:0032368 regulation of lipid transport; GO:0031344 regulation of cell projection organization; GO:0050896 response to stimulus; GO:0032429 regulation of phospholipase A2 activity; GO:0070201 regulation of establishment of protein localization; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0043066 negative regulation of apoptotic process; GO:0051961 negative regulation of nervous system development; GO:0043277 apoptotic cell clearance; GO:0001523 retinoid metabolic process; GO:0009987 cellular process; GO:1901214 regulation of neuron death; GO:0045595 regulation of cell differentiation; GO:0010875 positive regulation of cholesterol efflux; GO:0051049 regulation of transport; GO:1903053 regulation of extracellular matrix organization; GO:0033043 regulation of organelle organization; GO:0048585 negative regulation of response to stimulus; GO:0006897 endocytosis; GO:0042953 lipoprotein transport; GO:0048518 positive regulation of biological process; GO:0044767 single-organism developmental process; GO:0032370 positive regulation of lipid transport; GO:0006721 terpenoid metabolic process; GO:0051128 regulation of cellular component organization; GO:0040012 regulation of locomotion; GO:0032373 positive regulation of sterol transport; GO:0042981 regulation of apoptotic process; GO:0014910 regulation of smooth muscle cell migration; GO:0050767 regulation of neurogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0030425 dendrite; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0043025 neuronal cell body; GO:0032991 macromolecular complex; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005765 lysosomal membrane; GO:0005925 focal adhesion; GO:0030136 clathrin-coated vesicle; GO:0005622 intracellular; GO:0005764 lysosome; GO:0098589 membrane region; GO:0043005 neuron projection; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043233 organelle lumen; GO:0005924 cell-substrate adherens junction; GO:0000323 lytic vacuole; GO:0042995 cell projection; GO:0031226 intrinsic component of plasma membrane; GO:0030666 endocytic vesicle membrane; GO:0043235 receptor complex; GO:0070161 anchoring junction; GO:0031981 nuclear lumen; GO:0012506 vesicle membrane; GO:0005730 nucleolus; GO:0030135 coated vesicle; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005905 clathrin-coated pit; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0005912 adherens junction; GO:0005768 endosome; GO:0030139 endocytic vesicle; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0016021 integral component of membrane; GO:0098852 lytic vacuole membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0005634 nucleus; GO:0036477 somatodendritic compartment; GO:0044459 plasma membrane part; GO:0005774 vacuolar membrane; GO:0044297 cell body; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0003723 RNA binding; GO:0008565 protein transporter activity; GO:0034185 apolipoprotein binding; GO:0005102 receptor binding; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0038024 cargo receptor activity; GO:0022892 substrate-specific transporter activity; GO:0042954 lipoprotein transporter activity; GO:0005515 protein binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0002020 protease binding; GO:0030228 lipoprotein particle receptor activity; GO:0070325 lipoprotein particle receptor binding; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005041 low-density lipoprotein receptor activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005509 calcium ion binding; GO:0019899 enzyme binding; GO:0032403 protein complex binding; GO:0005215 transporter activity; ","K04550","LRP1; low-density lipoprotein receptor-related protein 1 (alpha-2-macroglobulin receptor)","hsa05144 Malaria - Homo sapiens (human); hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04979 Cholesterol metabolism - Homo sapiens (human); ","IPR026823; IPR001881; IPR000742; IPR011042; IPR009030; IPR032485; ","\"Complement Clr-like EGF domain; EGF-like calcium-binding domain; EGF-like domain; Six-bladed beta-propeller, TolB-like; Growth factor receptor cysteine-rich domain; Domain of unknown function DUF5050; \"\r"]
["Q07960","Rho GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=ARHGAP1","ARHGAP1",50.435,101.49,37.8,15,27,15,0.957,1.072,1.003,1.042,0.937,1.003,0.984,0.734,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0051345 positive regulation of hydrolase activity; GO:0023056 positive regulation of signaling; GO:0044093 positive regulation of molecular function; GO:0007266 Rho protein signal transduction; GO:0010647 positive regulation of cell communication; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:0051056 regulation of small GTPase mediated signal transduction; GO:0051716 cellular response to stimulus; GO:1902531 regulation of intracellular signal transduction; GO:0043547 positive regulation of GTPase activity; GO:0035556 intracellular signal transduction; GO:0048522 positive regulation of cellular process; GO:0007264 small GTPase mediated signal transduction; GO:0023052 signaling; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0065009 regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0009967 positive regulation of signal transduction; GO:0048584 positive regulation of response to stimulus; GO:0007265 Ras protein signal transduction; GO:0065007 biological regulation; ","GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0030674 protein binding, bridging; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0030695 GTPase regulator activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0017124 SH3 domain binding; GO:0005070 SH3/SH2 adaptor activity; GO:0050839 cell adhesion molecule binding; GO:0035591 signaling adaptor activity; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0045296 cadherin binding; GO:0060090 binding, bridging; GO:0019904 protein domain specific binding; GO:0008047 enzyme activator activity; GO:0005096 GTPase activator activity; ","K18470",null,null,"IPR001251; IPR008936; IPR000198; ","CRAL-TRIO lipid binding domain; Rho GTPase activation protein; Rho GTPase-activating protein domain; \r"]
["Q08211","ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9","DHX9",140.96,226.37,25.1,26,44,26,0.974,0.95,0.882,1.101,1.051,1.073,1.149,0.0129,"nucleus\r","GO:0001649 osteoblast differentiation; GO:0032481 positive regulation of type I interferon production; GO:0065008 regulation of biological quality; GO:1903608 protein localization to cytoplasmic stress granule; GO:0010608 posttranscriptional regulation of gene expression; GO:0043489 RNA stabilization; GO:0048869 cellular developmental process; GO:0032392 DNA geometric change; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0033365 protein localization to organelle; GO:0043170 macromolecule metabolic process; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0071103 DNA conformation change; GO:0006396 RNA processing; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0001503 ossification; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0032501 multicellular organismal process; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0016071 mRNA metabolic process; GO:0048255 mRNA stabilization; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0032479 regulation of type I interferon production; GO:0006725 cellular aromatic compound metabolic process; GO:0001819 positive regulation of cytokine production; GO:0060255 regulation of macromolecule metabolic process; GO:0051239 regulation of multicellular organismal process; GO:0043487 regulation of RNA stability; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0000398 mRNA splicing, via spliceosome; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0070934 CRD-mediated mRNA stabilization; GO:0034641 cellular nitrogen compound metabolic process; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0008380 RNA splicing; GO:0032508 DNA duplex unwinding; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:0043488 regulation of mRNA stability; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0070727 cellular macromolecule localization; GO:0051276 chromosome organization; GO:0044767 single-organism developmental process; GO:0006996 organelle organization; GO:0048511 rhythmic process; GO:0001817 regulation of cytokine production; GO:0010467 gene expression; GO:0051179 localization; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0031974 membrane-enclosed lumen; GO:0005815 microtubule organizing center; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0097165 nuclear stress granule; GO:0070937 CRD-mediated mRNA stability complex; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005813 centrosome; GO:0035770 ribonucleoprotein granule; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0008026 ATP-dependent helicase activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0016887 ATPase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0001085 RNA polymerase II transcription factor binding; GO:0005488 binding; GO:0004003 ATP-dependent DNA helicase activity; GO:0032550 purine ribonucleoside binding; GO:0004004 ATP-dependent RNA helicase activity; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0008094 DNA-dependent ATPase activity; GO:0003678 DNA helicase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003723 RNA binding; GO:0003677 DNA binding; GO:0005524 ATP binding; GO:0070035 purine NTP-dependent helicase activity; GO:0004386 helicase activity; GO:0008186 RNA-dependent ATPase activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003724 RNA helicase activity; GO:0042623 ATPase activity, coupled; GO:0003676 nucleic acid binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0008134 transcription factor binding; GO:0036094 small molecule binding; ","K13184",null,null,"IPR007502; IPR011545; IPR011709; IPR014720; IPR014001; IPR027417; IPR001650; ","\"Helicase-associated domain; DEAD/DEAH box helicase domain; Domain of unknown function DUF1605; Double-stranded RNA-binding domain; Helicase superfamily 1/2, ATP-binding domain; P-loop containing nucleoside triphosphate hydrolase; Helicase, C-terminal; \"\r"]
["Q08257","Quinone oxidoreductase OS=Homo sapiens OX=9606 GN=CRYZ","CRYZ",35.206,30.755,22.8,8,15,8,1.087,1.073,0.991,0.931,0.942,0.924,0.888,0.0159,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0071466 cellular response to xenobiotic stimulus; GO:0016043 cellular component organization; GO:0007601 visual perception; GO:0051260 protein homooligomerization; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0050877 neurological system process; GO:0051259 protein oligomerization; GO:0051289 protein homotetramerization; GO:0008152 metabolic process; GO:0009410 response to xenobiotic stimulus; GO:0006805 xenobiotic metabolic process; GO:0022607 cellular component assembly; GO:0051262 protein tetramerization; GO:0065003 macromolecular complex assembly; GO:0044248 cellular catabolic process; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0070887 cellular response to chemical stimulus; GO:0051716 cellular response to stimulus; GO:0007600 sensory perception; GO:0071822 protein complex subunit organization; GO:0003008 system process; GO:0055114 oxidation-reduction process; GO:0050953 sensory perception of light stimulus; GO:0032501 multicellular organismal process; GO:0043933 macromolecular complex subunit organization; GO:0042178 xenobiotic catabolic process; GO:0042221 response to chemical; GO:0044710 single-organism metabolic process; GO:0070271 protein complex biogenesis; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:0003723 RNA binding; GO:1901265 nucleoside phosphate binding; GO:0003730 mRNA 3'-UTR binding; GO:0070402 NADPH binding; GO:0043167 ion binding; GO:0000166 nucleotide binding; GO:0008270 zinc ion binding; GO:0048037 cofactor binding; GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; GO:0016491 oxidoreductase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0003729 mRNA binding; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0050661 NADP binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0043168 anion binding; GO:0003960 NADPH:quinone reductase activity; GO:0050662 coenzyme binding; GO:0036094 small molecule binding; ","K00344",null,null,"IPR011032; IPR020843; IPR016040; IPR013154; IPR013149; ","\"GroES-like; Polyketide synthase, enoylreductase domain; NAD(P)-binding domain; Alcohol dehydrogenase, N-terminal; Alcohol dehydrogenase, C-terminal; \"\r"]
["Q08379","Golgin subfamily A member 2 OS=Homo sapiens OX=9606 GN=GOLGA2","GOLGA2",113.08,31.638,6.8,5,6,5,1.054,0.986,1.188,0.973,0.862,0.952,0.863,0.0927,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0043413 macromolecule glycosylation; GO:0032270 positive regulation of cellular protein metabolic process; GO:0048208 COPII vesicle coating; GO:0031109 microtubule polymerization or depolymerization; GO:0022414 reproductive process; GO:0051443 positive regulation of ubiquitin-protein transferase activity; GO:0009891 positive regulation of biosynthetic process; GO:0032091 negative regulation of protein binding; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0048308 organelle inheritance; GO:0065003 macromolecular complex assembly; GO:0044093 positive regulation of molecular function; GO:0048199 vesicle targeting, to, from or within Golgi; GO:0044702 single organism reproductive process; GO:0051347 positive regulation of transferase activity; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0060050 positive regulation of protein glycosylation; GO:0006486 protein glycosylation; GO:0000278 mitotic cell cycle; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0010559 regulation of glycoprotein biosynthetic process; GO:0000212 meiotic spindle organization; GO:0044763 single-organism cellular process; GO:0009100 glycoprotein metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0010506 regulation of autophagy; GO:0090166 Golgi disassembly; GO:0006810 transport; GO:0000226 microtubule cytoskeleton organization; GO:0007030 Golgi organization; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0007020 microtubule nucleation; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0090307 mitotic spindle assembly; GO:0006464 cellular protein modification process; GO:0051301 cell division; GO:0097435 supramolecular fiber organization; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0000003 reproduction; GO:0051640 organelle localization; GO:0046907 intracellular transport; GO:0051260 protein homooligomerization; GO:0048313 Golgi inheritance; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0051297 centrosome organization; GO:0007051 spindle organization; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:1903047 mitotic cell cycle process; GO:0051259 protein oligomerization; GO:0009889 regulation of biosynthetic process; GO:0051338 regulation of transferase activity; GO:1901135 carbohydrate derivative metabolic process; GO:0007010 cytoskeleton organization; GO:0006461 protein complex assembly; GO:0090114 COPII-coated vesicle budding; GO:0016192 vesicle-mediated transport; GO:1903018 regulation of glycoprotein metabolic process; GO:0044238 primary metabolic process; GO:0051656 establishment of organelle localization; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0007017 microtubule-based process; GO:1904666 regulation of ubiquitin protein ligase activity; GO:0031330 negative regulation of cellular catabolic process; GO:0051247 positive regulation of protein metabolic process; GO:0051438 regulation of ubiquitin-protein transferase activity; GO:0031398 positive regulation of protein ubiquitination; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0061024 membrane organization; GO:0006900 membrane budding; GO:1904668 positive regulation of ubiquitin protein ligase activity; GO:0000280 nuclear division; GO:0043412 macromolecule modification; GO:0031328 positive regulation of cellular biosynthetic process; GO:0051179 localization; GO:0006901 vesicle coating; GO:0090306 spindle assembly involved in meiosis; GO:0048207 vesicle targeting, rough ER to cis-Golgi; GO:0010256 endomembrane system organization; GO:0007067 mitotic nuclear division; GO:1903008 organelle disassembly; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0051234 establishment of localization; GO:0031396 regulation of protein ubiquitination; GO:0008356 asymmetric cell division; GO:1903020 positive regulation of glycoprotein metabolic process; GO:0051225 spindle assembly; GO:0051649 establishment of localization in cell; GO:0022607 cellular component assembly; GO:0051262 protein tetramerization; GO:0009893 positive regulation of metabolic process; GO:0051650 establishment of vesicle localization; GO:0009101 glycoprotein biosynthetic process; GO:0071822 protein complex subunit organization; GO:0031326 regulation of cellular biosynthetic process; GO:0051098 regulation of binding; GO:0048522 positive regulation of cellular process; GO:0051321 meiotic cell cycle; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0051100 negative regulation of binding; GO:0051258 protein polymerization; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:1902850 microtubule cytoskeleton organization involved in mitosis; GO:0044092 negative regulation of molecular function; GO:0010507 negative regulation of autophagy; GO:0046785 microtubule polymerization; GO:0070271 protein complex biogenesis; GO:0036211 protein modification process; GO:0016043 cellular component organization; GO:1903046 meiotic cell cycle process; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:0060255 regulation of macromolecule metabolic process; GO:0048285 organelle fission; GO:0048193 Golgi vesicle transport; GO:0060049 regulation of protein glycosylation; GO:0031324 negative regulation of cellular metabolic process; GO:0006903 vesicle targeting; GO:0090161 Golgi ribbon formation; GO:0071704 organic substance metabolic process; GO:0043393 regulation of protein binding; GO:1903322 positive regulation of protein modification by small protein conjugation or removal; GO:0051289 protein homotetramerization; GO:0070925 organelle assembly; GO:0051648 vesicle localization; GO:0009895 negative regulation of catabolic process; GO:0007052 mitotic spindle organization; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0070085 glycosylation; GO:0010560 positive regulation of glycoprotein biosynthetic process; GO:0043623 cellular protein complex assembly; GO:0034622 cellular macromolecular complex assembly; GO:0016050 vesicle organization; GO:0031401 positive regulation of protein modification process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0043085 positive regulation of catalytic activity; GO:0051641 cellular localization; GO:0043933 macromolecular complex subunit organization; GO:0034645 cellular macromolecule biosynthetic process; GO:0031023 microtubule organizing center organization; GO:0051246 regulation of protein metabolic process; GO:0022411 cellular component disassembly; GO:0007126 meiotic nuclear division; GO:0022402 cell cycle process; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005874 microtubule; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0005801 cis-Golgi network; GO:0044424 intracellular part; GO:0099512 supramolecular fiber; GO:0005623 cell; GO:0099080 supramolecular complex; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0072686 mitotic spindle; GO:0005856 cytoskeleton; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0098791 Golgi subcompartment; GO:0044431 Golgi apparatus part; GO:0043227 membrane-bounded organelle; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0000922 spindle pole; GO:0098588 bounding membrane of organelle; GO:0032580 Golgi cisterna membrane; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0030134 ER to Golgi transport vesicle; GO:0005795 Golgi stack; GO:0012505 endomembrane system; GO:0030135 coated vesicle; GO:0005819 spindle; GO:0099081 supramolecular polymer; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005793 endoplasmic reticulum-Golgi intermediate compartment; GO:0030133 transport vesicle; GO:0005794 Golgi apparatus; GO:0000137 Golgi cis cisterna; GO:0031985 Golgi cisterna; GO:0044444 cytoplasmic part; GO:0031984 organelle subcompartment; ","GO:0000149 SNARE binding; GO:0061676 importin-alpha family protein binding; GO:0050839 cell adhesion molecule binding; GO:0008092 cytoskeletal protein binding; GO:0008017 microtubule binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0019901 protein kinase binding; GO:0015631 tubulin binding; GO:0005515 protein binding; GO:0019900 kinase binding; GO:0019905 syntaxin binding; GO:0019899 enzyme binding; ","K20358"]
["Q08380","Galectin-3-binding protein OS=Homo sapiens OX=9606 GN=LGALS3BP","LGALS3BP",65.33,64.038,17.9,9,12,9,0.926,0.923,0.922,1.086,1.098,1.084,1.179,1.27e-06,"extracellular\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0051716 cellular response to stimulus; GO:0006950 response to stress; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0002576 platelet degranulation; GO:0044699 single-organism process; GO:0006897 endocytosis; GO:0023052 signaling; GO:0050896 response to stimulus; GO:0051234 establishment of localization; GO:0006810 transport; GO:0022610 biological adhesion; GO:0045055 regulated exocytosis; GO:0007165 signal transduction; GO:0050789 regulation of biological process; GO:1902578 single-organism localization; GO:0007154 cell communication; GO:0032940 secretion by cell; GO:0006968 cellular defense response; GO:0007155 cell adhesion; GO:0006898 receptor-mediated endocytosis; GO:0006952 defense response; GO:0051179 localization; GO:0009987 cellular process; GO:0006887 exocytosis; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0016020 membrane; GO:0042827 platelet dense granule; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0031012 extracellular matrix; GO:0043226 organelle; GO:0072562 blood microparticle; GO:0060205 cytoplasmic vesicle lumen; GO:0005578 proteinaceous extracellular matrix; GO:0031089 platelet dense granule lumen; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0038024 cargo receptor activity; GO:0005044 scavenger receptor activity; GO:0060089 molecular transducer activity; GO:0005515 protein binding; GO:0004872 receptor activity; GO:0005488 binding; ","K17300",null,null,"IPR001190; IPR017448; IPR011705; IPR000210; ","SRCR domain; SRCR-like domain; BTB/Kelch-associated; BTB/POZ domain; \r"]
["Q08722","Leukocyte surface antigen CD47 OS=Homo sapiens OX=9606 GN=CD47","CD47",35.213,16.263,10.8,4,9,4,1.124,1.016,1.06,0.912,0.952,0.946,0.878,0.0159,"plasma membrane\r","GO:0050863 regulation of T cell activation; GO:0044700 single organism signaling; GO:0060627 regulation of vesicle-mediated transport; GO:0002694 regulation of leukocyte activation; GO:0045321 leukocyte activation; GO:0051674 localization of cell; GO:0007166 cell surface receptor signaling pathway; GO:0044699 single-organism process; GO:0051249 regulation of lymphocyte activation; GO:0031347 regulation of defense response; GO:0009607 response to biotic stimulus; GO:0006909 phagocytosis; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0009605 response to external stimulus; GO:0022610 biological adhesion; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0032879 regulation of localization; GO:0032103 positive regulation of response to external stimulus; GO:0007155 cell adhesion; GO:0030198 extracellular matrix organization; GO:0050764 regulation of phagocytosis; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0050729 positive regulation of inflammatory response; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0051251 positive regulation of lymphocyte activation; GO:0048870 cell motility; GO:0007229 integrin-mediated signaling pathway; GO:0023052 signaling; GO:0051704 multi-organism process; GO:0002444 myeloid leukocyte mediated immunity; GO:0008228 opsonization; GO:0051050 positive regulation of transport; GO:0006810 transport; GO:0050865 regulation of cell activation; GO:0050900 leukocyte migration; GO:0050789 regulation of biological process; GO:0032940 secretion by cell; GO:0048583 regulation of response to stimulus; GO:0002682 regulation of immune system process; GO:0040011 locomotion; GO:0043299 leukocyte degranulation; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0016477 cell migration; GO:0002283 neutrophil activation involved in immune response; GO:0042127 regulation of cell proliferation; GO:0002252 immune effector process; GO:0045807 positive regulation of endocytosis; GO:0043207 response to external biotic stimulus; GO:0080134 regulation of response to stress; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0050867 positive regulation of cell activation; GO:0031349 positive regulation of defense response; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0043062 extracellular structure organization; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0009617 response to bacterium; GO:0030100 regulation of endocytosis; GO:0045785 positive regulation of cell adhesion; GO:0022409 positive regulation of cell-cell adhesion; GO:0051049 regulation of transport; GO:0016192 vesicle-mediated transport; GO:0050766 positive regulation of phagocytosis; GO:0032101 regulation of response to external stimulus; GO:0002376 immune system process; GO:0006897 endocytosis; GO:0043312 neutrophil degranulation; GO:1903039 positive regulation of leukocyte cell-cell adhesion; GO:0048518 positive regulation of biological process; GO:0002263 cell activation involved in immune response; GO:0022407 regulation of cell-cell adhesion; GO:0030155 regulation of cell adhesion; GO:0002366 leukocyte activation involved in immune response; GO:0002696 positive regulation of leukocyte activation; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0050870 positive regulation of T cell activation; GO:0002684 positive regulation of immune system process; GO:0050727 regulation of inflammatory response; GO:0006928 movement of cell or subcellular component; GO:0001775 cell activation; GO:0051128 regulation of cellular component organization; GO:0048584 positive regulation of response to stimulus; GO:0006955 immune response; GO:0051179 localization; GO:0008284 positive regulation of cell proliferation; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:0006887 exocytosis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0070821 tertiary granule membrane; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0035579 specific granule membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0031226 intrinsic component of plasma membrane; GO:0098588 bounding membrane of organelle; GO:0070820 tertiary granule; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0030667 secretory granule membrane; GO:0044459 plasma membrane part; GO:0042581 specific granule; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0038023 signaling receptor activity; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0070053 thrombospondin receptor activity; GO:0005488 binding; GO:0005515 protein binding; GO:0004871 signal transducer activity; ","K06266","CD47; CD47 antigen (Rh-related antigen, integrin-associated signal transducer)","hsa04512 ECM-receptor interaction - Homo sapiens (human); ","IPR013147; IPR007110; IPR013783; IPR013270; ","CD47 transmembrane; Immunoglobulin-like domain; Immunoglobulin-like fold; CD47 immunoglobulin-like; \r"]
["Q08945","FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1","SSRP1",81.074,37.288,7.9,5,8,5,0.963,0.907,0.926,1.051,1.034,1.133,1.151,0.0135,"nucleus\r","GO:0097659 nucleic acid-templated transcription; GO:0023051 regulation of signaling; GO:0009058 biosynthetic process; GO:0006354 DNA-templated transcription, elongation; GO:0044237 cellular metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0010646 regulation of cell communication; GO:0043170 macromolecule metabolic process; GO:0051716 cellular response to stimulus; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0006260 DNA replication; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0006259 DNA metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:1901796 regulation of signal transduction by p53 class mediator; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0009966 regulation of signal transduction; GO:0006355 regulation of transcription, DNA-templated; GO:1902531 regulation of intracellular signal transduction; GO:0006950 response to stress; GO:0006368 transcription elongation from RNA polymerase II promoter; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0006974 cellular response to DNA damage stimulus; GO:0006281 DNA repair; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006366 transcription from RNA polymerase II promoter; GO:0010467 gene expression; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005730 nucleolus; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0005694 chromosome; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003677 DNA binding; GO:0003723 RNA binding; GO:0005515 protein binding; GO:0003682 chromatin binding; GO:0005488 binding; GO:0003676 nucleic acid binding; ","K09272",null,null,"IPR013719; IPR011993; IPR009071; IPR024954; ","Domain of unknown function DUF1747; PH domain-like; High mobility group box domain; SSRP1 domain; \r"]
["Q09028","Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4","RBBP4",47.655,24.65,21.4,9,14,3,0.969,1.008,0.952,1.02,1.024,1.033,1.051,0.0457,"cyto_nucl\r","GO:0044085 cellular component biogenesis; GO:0097659 nucleic acid-templated transcription; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0008285 negative regulation of cell proliferation; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0010646 regulation of cell communication; GO:0034724 DNA replication-independent nucleosome organization; GO:0006334 nucleosome assembly; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0009719 response to endogenous stimulus; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:1901652 response to peptide; GO:0051726 regulation of cell cycle; GO:0031497 chromatin assembly; GO:0098732 macromolecule deacylation; GO:0006476 protein deacetylation; GO:0071824 protein-DNA complex subunit organization; GO:0071103 DNA conformation change; GO:0010468 regulation of gene expression; GO:0006333 chromatin assembly or disassembly; GO:0018130 heterocycle biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0034508 centromere complex assembly; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0043044 ATP-dependent chromatin remodeling; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0016070 RNA metabolic process; GO:0065004 protein-DNA complex assembly; GO:1903506 regulation of nucleic acid-templated transcription; GO:0010243 response to organonitrogen compound; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0043434 response to peptide hormone; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0035601 protein deacylation; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006464 cellular protein modification process; GO:0045814 negative regulation of gene expression, epigenetic; GO:0006325 chromatin organization; GO:0036211 protein modification process; GO:0034080 CENP-A containing nucleosome assembly; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0034728 nucleosome organization; GO:0006338 chromatin remodeling; GO:0006260 DNA replication; GO:0043486 histone exchange; GO:0006725 cellular aromatic compound metabolic process; GO:0042127 regulation of cell proliferation; GO:0061641 CENP-A containing chromatin organization; GO:0060255 regulation of macromolecule metabolic process; GO:0006259 DNA metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0016570 histone modification; GO:1901700 response to oxygen-containing compound; GO:0044267 cellular protein metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0006323 DNA packaging; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0034723 DNA replication-dependent nucleosome organization; GO:0009889 regulation of biosynthetic process; GO:1901796 regulation of signal transduction by p53 class mediator; GO:0006335 DNA replication-dependent nucleosome assembly; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0016569 covalent chromatin modification; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0009966 regulation of signal transduction; GO:0006336 DNA replication-independent nucleosome assembly; GO:0016575 histone deacetylation; GO:0034622 cellular macromolecular complex assembly; GO:0006355 regulation of transcription, DNA-templated; GO:1902531 regulation of intracellular signal transduction; GO:0010629 negative regulation of gene expression; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0010033 response to organic substance; GO:0060416 response to growth hormone; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0051252 regulation of RNA metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0040029 regulation of gene expression, epigenetic; GO:0031055 chromatin remodeling at centromere; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0051276 chromosome organization; GO:0006996 organelle organization; GO:0010467 gene expression; GO:0009725 response to hormone; GO:0043412 macromolecule modification; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0005737 cytoplasm; GO:0033186 CAF-1 complex; GO:0032991 macromolecular complex; GO:0017053 transcriptional repressor complex; GO:0044424 intracellular part; GO:0070603 SWI/SNF superfamily-type complex; GO:0005623 cell; GO:0000118 histone deacetylase complex; GO:0044422 organelle part; GO:0090568 nuclear transcriptional repressor complex; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0016589 NURF complex; GO:0016580 Sin3 complex; GO:0044454 nuclear chromosome part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005694 chromosome; GO:0090545 CHD-type complex; GO:0000790 nuclear chromatin; GO:0016581 NuRD complex; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0035097 histone methyltransferase complex; GO:1990234 transferase complex; GO:0005829 cytosol; GO:0034708 methyltransferase complex; GO:0031010 ISWI-type complex; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0070822 Sin3-type complex; GO:0000785 chromatin; GO:0035098 ESC/E(Z) complex; GO:0000228 nuclear chromosome; GO:0031519 PcG protein complex; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0004407 histone deacetylase activity; GO:0042393 histone binding; GO:0042826 histone deacetylase binding; GO:0033558 protein deacetylase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0019213 deacetylase activity; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; GO:0019899 enzyme binding; ","K10752","RBBP4; histone-binding protein RBBP4","hsa04218 Cellular senescence - Homo sapiens (human); ","IPR022052; IPR017986; IPR015943; ","\"Histone-binding protein RBBP4, N-terminal; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain; \"\r"]
["Q09161","Nuclear cap-binding protein subunit 1 OS=Homo sapiens OX=9606 GN=NCBP1","NCBP1",91.838,8.1538,1.4,1,2,1,0.917,0.904,0.983,1.031,1.112,1.05,1.139,0.0196,"nucleus\r","GO:0044700 single organism signaling; GO:0050658 RNA transport; GO:0007166 cell surface receptor signaling pathway; GO:0010608 posttranscriptional regulation of gene expression; GO:0097659 nucleic acid-templated transcription; GO:0051169 nuclear transport; GO:0006354 DNA-templated transcription, elongation; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0045927 positive regulation of growth; GO:0001558 regulation of cell growth; GO:0008152 metabolic process; GO:0015931 nucleobase-containing compound transport; GO:0031440 regulation of mRNA 3'-end processing; GO:0009719 response to endogenous stimulus; GO:0070848 response to growth factor; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0043170 macromolecule metabolic process; GO:0008104 protein localization; GO:0006396 RNA processing; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0030307 positive regulation of cell growth; GO:0080090 regulation of primary metabolic process; GO:0098787 mRNA cleavage involved in mRNA processing; GO:0044763 single-organism cellular process; GO:0034249 negative regulation of cellular amide metabolic process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0050684 regulation of mRNA processing; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0006611 protein export from nucleus; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0031047 gene silencing by RNA; GO:0032269 negative regulation of cellular protein metabolic process; GO:0006402 mRNA catabolic process; GO:1901698 response to nitrogen compound; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006913 nucleocytoplasmic transport; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0090305 nucleic acid phosphodiester bond hydrolysis; GO:0006379 mRNA cleavage; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0045292 mRNA cis splicing, via spliceosome; GO:0051028 mRNA transport; GO:0017148 negative regulation of translation; GO:0098789 pre-mRNA cleavage required for polyadenylation; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0051236 establishment of RNA localization; GO:0044270 cellular nitrogen compound catabolic process; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0098781 ncRNA transcription; GO:0000375 RNA splicing, via transesterification reactions; GO:0071774 response to fibroblast growth factor; GO:0016073 snRNA metabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0044248 cellular catabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0034613 cellular protein localization; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0008380 RNA splicing; GO:0071359 cellular response to dsRNA; GO:0051254 positive regulation of RNA metabolic process; GO:0006370 7-methylguanosine mRNA capping; GO:0006403 RNA localization; GO:0006405 RNA export from nucleus; GO:0006368 transcription elongation from RNA polymerase II promoter; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0071407 cellular response to organic cyclic compound; GO:0071702 organic substance transport; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0034248 regulation of cellular amide metabolic process; GO:0045184 establishment of protein localization; GO:1903311 regulation of mRNA metabolic process; GO:0009890 negative regulation of biosynthetic process; GO:0031325 positive regulation of cellular metabolic process; GO:0031442 positive regulation of mRNA 3'-end processing; GO:0051179 localization; GO:0035195 gene silencing by miRNA; GO:0042795 snRNA transcription from RNA polymerase II promoter; GO:0035194 posttranscriptional gene silencing by RNA; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0051168 nuclear export; GO:0071363 cellular response to growth factor stimulus; GO:0008543 fibroblast growth factor receptor signaling pathway; GO:0051234 establishment of localization; GO:0006353 DNA-templated transcription, termination; GO:0071427 mRNA-containing ribonucleoprotein complex export from nucleus; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0009893 positive regulation of metabolic process; GO:0050657 nucleic acid transport; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:1901361 organic cyclic compound catabolic process; GO:0033036 macromolecule localization; GO:0070887 cellular response to chemical stimulus; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0034470 ncRNA processing; GO:0008334 histone mRNA metabolic process; GO:0010468 regulation of gene expression; GO:0036260 RNA capping; GO:0031326 regulation of cellular biosynthetic process; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0043331 response to dsRNA; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:1903313 positive regulation of mRNA metabolic process; GO:0071166 ribonucleoprotein complex localization; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:0006401 RNA catabolic process; GO:0009301 snRNA transcription; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:1901699 cellular response to nitrogen compound; GO:0019222 regulation of metabolic process; GO:0070918 production of small RNA involved in gene silencing by RNA; GO:0031123 RNA 3'-end processing; GO:0050685 positive regulation of mRNA processing; GO:0040008 regulation of growth; GO:0006725 cellular aromatic compound metabolic process; GO:0031124 mRNA 3'-end processing; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0071310 cellular response to organic substance; GO:0009452 7-methylguanosine RNA capping; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0031053 primary miRNA processing; GO:0006886 intracellular protein transport; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0006406 mRNA export from nucleus; GO:0044265 cellular macromolecule catabolic process; GO:0006369 termination of RNA polymerase II transcription; GO:0010629 negative regulation of gene expression; GO:0016441 posttranscriptional gene silencing; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0040029 regulation of gene expression, epigenetic; GO:0070727 cellular macromolecule localization; GO:0016458 gene silencing; GO:0035196 production of miRNAs involved in gene silencing by miRNA; GO:0090501 RNA phosphodiester bond hydrolysis; GO:0071426 ribonucleoprotein complex export from nucleus; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0051246 regulation of protein metabolic process; GO:0006417 regulation of translation; GO:0071495 cellular response to endogenous stimulus; GO:0031050 dsRNA fragmentation; GO:0006366 transcription from RNA polymerase II promoter; GO:0044344 cellular response to fibroblast growth factor stimulus; GO:0009057 macromolecule catabolic process; GO:0006446 regulation of translational initiation; GO:0051248 negative regulation of protein metabolic process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0010467 gene expression; GO:0051128 regulation of cellular component organization; GO:0031327 negative regulation of cellular biosynthetic process; GO:0034660 ncRNA metabolic process; GO:0009056 catabolic process; GO:0071705 nitrogen compound transport; GO:0065007 biological regulation; GO:0046700 heterocycle catabolic process; ","GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0034518 RNA cap binding complex; GO:0005829 cytosol; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0005846 nuclear cap binding complex; GO:0005845 mRNA cap binding complex; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003729 mRNA binding; GO:0003723 RNA binding; GO:0000339 RNA cap binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; ","K12882","NCBP1; nuclear cap-binding protein subunit 1","hsa03040 Spliceosome - Homo sapiens (human); hsa03015 mRNA surveillance pathway - Homo sapiens (human); hsa03013 RNA transport - Homo sapiens (human); ","IPR015174; IPR016024; IPR015172; IPR003890; IPR016021; ","\"MIF4G-like, type 2; Armadillo-type fold; MIF4G-like, type 1; MIF4G-like, type 3; MIF4G-like domain; \"\r"]
["Q0VD83","Apolipoprotein B receptor OS=Homo sapiens OX=9606 GN=APOBR","APOBR",114.87,10.132,3.1,3,3,3,0.831,0.933,0.892,1.135,1.112,1.091,1.257,2.98E-3,"nucleus\r","GO:0046486 glycerolipid metabolic process; GO:1901615 organic hydroxy compound metabolic process; GO:1902652 secondary alcohol metabolic process; GO:0006066 alcohol metabolic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0016125 sterol metabolic process; GO:0042157 lipoprotein metabolic process; GO:0071704 organic substance metabolic process; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:1902578 single-organism localization; GO:0006639 acylglycerol metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006898 receptor-mediated endocytosis; GO:0033036 macromolecule localization; GO:0009987 cellular process; GO:0044765 single-organism transport; GO:0006629 lipid metabolic process; GO:0006638 neutral lipid metabolic process; GO:0008203 cholesterol metabolic process; GO:0006869 lipid transport; GO:0016192 vesicle-mediated transport; GO:0044281 small molecule metabolic process; GO:0008202 steroid metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0010876 lipid localization; GO:0071702 organic substance transport; GO:0006897 endocytosis; GO:0044238 primary metabolic process; GO:0006810 transport; GO:0006641 triglyceride metabolic process; GO:0044710 single-organism metabolic process; GO:0051179 localization; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005615 extracellular space; GO:0071944 cell periphery; GO:0034362 low-density lipoprotein particle; GO:0034358 plasma lipoprotein particle; GO:0034385 triglyceride-rich plasma lipoprotein particle; GO:0032991 macromolecular complex; GO:0042627 chylomicron; GO:0005623 cell; GO:0034361 very-low-density lipoprotein particle; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0032994 protein-lipid complex; GO:0044464 cell part; GO:1990777 lipoprotein particle; ","GO:0030228 lipoprotein particle receptor activity; GO:0038024 cargo receptor activity; GO:0030229 very-low-density lipoprotein particle receptor activity; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; "]
["Q0VDF9","Heat shock 70 kDa protein 14 OS=Homo sapiens OX=9606 GN=HSPA14","HSPA14",54.794,6.8111,7.5,4,4,4,0.908,0.917,0.892,1.116,1.111,1.053,1.207,0.000761,"extracellular\r","GO:0051083 'de novo' cotranslational protein folding; GO:0006457 protein folding; GO:0006458 'de novo' protein folding; GO:0009987 cellular process; ","GO:0016020 membrane; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ",{"$nulls":3},"IPR029047; ","\"Heat shock protein 70kD, peptide-binding domain; \"\r"]
["Q10713","Mitochondrial-processing peptidase subunit alpha OS=Homo sapiens OX=9606 GN=PMPCA","PMPCA",58.252,10.164,8.8,5,6,5,0.978,0.938,0.958,1.047,1.013,1.069,1.089,0.0127,"mitochondria\r","GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0072594 establishment of protein localization to organelle; GO:0006839 mitochondrial transport; GO:0044267 cellular protein metabolic process; GO:0016485 protein processing; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0071704 organic substance metabolic process; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0007005 mitochondrion organization; GO:0006886 intracellular protein transport; GO:0006626 protein targeting to mitochondrion; GO:0006508 proteolysis; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0033365 protein localization to organelle; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0034982 mitochondrial protein processing; GO:0006627 protein processing involved in protein targeting to mitochondrion; GO:0071702 organic substance transport; GO:0070585 protein localization to mitochondrion; GO:0044238 primary metabolic process; GO:0051641 cellular localization; GO:0006810 transport; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0006996 organelle organization; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0051179 localization; GO:0051604 protein maturation; GO:0072655 establishment of protein localization to mitochondrion; GO:0071840 cellular component organization or biogenesis; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0044429 mitochondrial part; GO:0031090 organelle membrane; GO:0031967 organelle envelope; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0031975 envelope; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0004175 endopeptidase activity; GO:0004222 metalloendopeptidase activity; GO:0008233 peptidase activity; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0016787 hydrolase activity; GO:0008237 metallopeptidase activity; GO:0008270 zinc ion binding; ","K01412",null,null,"IPR007863; IPR011765; IPR011249; IPR011237; ","\"Peptidase M16, C-terminal; Peptidase M16, N-terminal; Metalloenzyme, LuxS/M16 peptidase-like; Peptidase M16 domain; \"\r"]
["Q12765","Secernin-1 OS=Homo sapiens OX=9606 GN=SCRN1","SCRN1",46.382,39.935,11.4,4,5,4,0.959,1.067,1.12,0.85,1.077,0.942,0.912,0.314,"cyto_nucl\r","GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0044238 primary metabolic process; GO:0051234 establishment of localization; GO:0071704 organic substance metabolic process; GO:0006810 transport; GO:0008152 metabolic process; GO:1902578 single-organism localization; GO:0032940 secretion by cell; GO:0006508 proteolysis; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0051179 localization; GO:0009987 cellular process; GO:0006887 exocytosis; GO:0044765 single-organism transport; GO:0046903 secretion; ","GO:0016020 membrane; GO:0043229 intracellular organelle; GO:0031090 organelle membrane; GO:0005635 nuclear envelope; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031965 nuclear membrane; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0031975 envelope; GO:0043227 membrane-bounded organelle; GO:0044428 nuclear part; ","GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0016787 hydrolase activity; GO:0008233 peptidase activity; GO:0008238 exopeptidase activity; GO:0005515 protein binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016805 dipeptidase activity; ","K14358"]
["Q12797","Aspartyl/asparaginyl beta-hydroxylase OS=Homo sapiens OX=9606 GN=ASPH","ASPH",85.862,85.924,18.1,11,15,11,1.057,1.112,1.082,0.904,0.891,0.927,0.837,0.000682,"plasma membrane\r","GO:0044700 single organism signaling; GO:0050850 positive regulation of calcium-mediated signaling; GO:2000273 positive regulation of receptor activity; GO:0009593 detection of chemical stimulus; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0009891 positive regulation of biosynthetic process; GO:0046683 response to organophosphorus; GO:0044237 cellular metabolic process; GO:1904427 positive regulation of calcium ion transmembrane transport; GO:0010469 regulation of receptor activity; GO:0005513 detection of calcium ion; GO:0008285 negative regulation of cell proliferation; GO:0008152 metabolic process; GO:0035107 appendage morphogenesis; GO:0032879 regulation of localization; GO:1901019 regulation of calcium ion transmembrane transporter activity; GO:0044093 positive regulation of molecular function; GO:0051606 detection of stimulus; GO:0044057 regulation of system process; GO:0032414 positive regulation of ion transmembrane transporter activity; GO:0009719 response to endogenous stimulus; GO:0060173 limb development; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:1901339 regulation of store-operated calcium channel activity; GO:0031638 zymogen activation; GO:0052548 regulation of endopeptidase activity; GO:0051716 cellular response to stimulus; GO:0014070 response to organic cyclic compound; GO:0010950 positive regulation of endopeptidase activity; GO:0097202 activation of cysteine-type endopeptidase activity; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0043269 regulation of ion transport; GO:0019932 second-messenger-mediated signaling; GO:0031323 regulation of cellular metabolic process; GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; GO:0032501 multicellular organismal process; GO:1903779 regulation of cardiac conduction; GO:0006810 transport; GO:0034762 regulation of transmembrane transport; GO:1903506 regulation of nucleic acid-templated transcription; GO:0010243 response to organonitrogen compound; GO:0051336 regulation of hydrolase activity; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:1901698 response to nitrogen compound; GO:2001257 regulation of cation channel activity; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:1901021 positive regulation of calcium ion transmembrane transporter activity; GO:0051223 regulation of protein transport; GO:0010171 body morphogenesis; GO:0032412 regulation of ion transmembrane transporter activity; GO:0060325 face morphogenesis; GO:0010952 positive regulation of peptidase activity; GO:0098662 inorganic cation transmembrane transport; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0034764 positive regulation of transmembrane transport; GO:0034220 ion transmembrane transport; GO:2001056 positive regulation of cysteine-type endopeptidase activity; GO:0042127 regulation of cell proliferation; GO:0030001 metal ion transport; GO:0044267 cellular protein metabolic process; GO:1901700 response to oxygen-containing compound; GO:0007389 pattern specification process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:1901341 positive regulation of store-operated calcium channel activity; GO:0032844 regulation of homeostatic process; GO:0051239 regulation of multicellular organismal process; GO:0060341 regulation of cellular localization; GO:0009653 anatomical structure morphogenesis; GO:0019722 calcium-mediated signaling; GO:0051345 positive regulation of hydrolase activity; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0014074 response to purine-containing compound; GO:0051171 regulation of nitrogen compound metabolic process; GO:0010959 regulation of metal ion transport; GO:1902680 positive regulation of RNA biosynthetic process; GO:0050848 regulation of calcium-mediated signaling; GO:0032880 regulation of protein localization; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:0032409 regulation of transporter activity; GO:1904062 regulation of cation transmembrane transport; GO:0018126 protein hydroxylation; GO:0051928 positive regulation of calcium ion transport; GO:0070588 calcium ion transmembrane transport; GO:0051254 positive regulation of RNA metabolic process; GO:0051282 regulation of sequestering of calcium ion; GO:1902531 regulation of intracellular signal transduction; GO:1901879 regulation of protein depolymerization; GO:0051924 regulation of calcium ion transport; GO:0010033 response to organic substance; GO:0030162 regulation of proteolysis; GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity; GO:0044238 primary metabolic process; GO:0060021 palate development; GO:2001259 positive regulation of cation channel activity; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0043270 positive regulation of ion transport; GO:0055085 transmembrane transport; GO:0051247 positive regulation of protein metabolic process; GO:1904951 positive regulation of establishment of protein localization; GO:1904064 positive regulation of cation transmembrane transport; GO:0006811 ion transport; GO:0031325 positive regulation of cellular metabolic process; GO:0031647 regulation of protein stability; GO:0043412 macromolecule modification; GO:0048584 positive regulation of response to stimulus; GO:0071248 cellular response to metal ion; GO:0031328 positive regulation of cellular biosynthetic process; GO:0051179 localization; GO:1903827 regulation of cellular protein localization; GO:0070838 divalent metal ion transport; GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling; GO:0003012 muscle system process; GO:0031585 regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0016485 protein processing; GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity; GO:0051234 establishment of localization; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0055117 regulation of cardiac muscle contraction; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0032846 positive regulation of homeostatic process; GO:0060322 head development; GO:0010035 response to inorganic substance; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0098655 cation transmembrane transport; GO:0031326 regulation of cellular biosynthetic process; GO:0051279 regulation of release of sequestered calcium ion into cytosol; GO:2000116 regulation of cysteine-type endopeptidase activity; GO:0055114 oxidation-reduction process; GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; GO:0090280 positive regulation of calcium ion import; GO:0048522 positive regulation of cellular process; GO:0022898 regulation of transmembrane transporter activity; GO:0032386 regulation of intracellular transport; GO:0090257 regulation of muscle system process; GO:0023052 signaling; GO:0006942 regulation of striated muscle contraction; GO:0010038 response to metal ion; GO:0051050 positive regulation of transport; GO:0010649 regulation of cell communication by electrical coupling; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0034767 positive regulation of ion transmembrane transport; GO:0032237 activation of store-operated calcium channel activity; GO:0071241 cellular response to inorganic substance; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0018197 peptidyl-aspartic acid modification; GO:0042264 peptidyl-aspartic acid hydroxylation; GO:0043244 regulation of protein complex disassembly; GO:0036211 protein modification process; GO:0052547 regulation of peptidase activity; GO:0048856 anatomical structure development; GO:0051222 positive regulation of protein transport; GO:0060324 face development; GO:0072511 divalent inorganic cation transport; GO:0090316 positive regulation of intracellular protein transport; GO:2000021 regulation of ion homeostasis; GO:0032411 positive regulation of transporter activity; GO:1903829 positive regulation of cellular protein localization; GO:0060255 regulation of macromolecule metabolic process; GO:1903522 regulation of blood circulation; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0008016 regulation of heart contraction; GO:0050896 response to stimulus; GO:0070201 regulation of establishment of protein localization; GO:0071704 organic substance metabolic process; GO:0045862 positive regulation of proteolysis; GO:0006936 muscle contraction; GO:0006812 cation transport; GO:0006816 calcium ion transport; GO:0060323 head morphogenesis; GO:0023056 positive regulation of signaling; GO:1903169 regulation of calcium ion transmembrane transport; GO:0051592 response to calcium ion; GO:0006508 proteolysis; GO:0010647 positive regulation of cell communication; GO:0010524 positive regulation of calcium ion transport into cytosol; GO:0009987 cellular process; GO:0033157 regulation of intracellular protein transport; GO:0033198 response to ATP; GO:0006355 regulation of transcription, DNA-templated; GO:0003008 system process; GO:0035556 intracellular signal transduction; GO:0098660 inorganic ion transmembrane transport; GO:0032388 positive regulation of intracellular transport; GO:0051049 regulation of transport; GO:0090279 regulation of calcium ion import; GO:0006937 regulation of muscle contraction; GO:0071277 cellular response to calcium ion; GO:0010556 regulation of macromolecule biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0018193 peptidyl-amino acid modification; GO:0048736 appendage development; GO:0034765 regulation of ion transmembrane transport; GO:0051281 positive regulation of release of sequestered calcium ion into cytosol; GO:0035108 limb morphogenesis; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0010522 regulation of calcium ion transport into cytosol; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0010467 gene expression; GO:0009967 positive regulation of signal transduction; GO:0051128 regulation of cellular component organization; GO:0051604 protein maturation; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0005938 cell cortex; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0099568 cytoplasmic region; GO:0014701 junctional sarcoplasmic reticulum membrane; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0033018 sarcoplasmic reticulum lumen; GO:0016528 sarcoplasm; GO:0005623 cell; GO:0044422 organelle part; GO:0033017 sarcoplasmic reticulum membrane; GO:0031974 membrane-enclosed lumen; GO:0098827 endoplasmic reticulum subcompartment; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0031227 intrinsic component of endoplasmic reticulum membrane; GO:0034702 ion channel complex; GO:1990351 transporter complex; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005788 endoplasmic reticulum lumen; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0034703 cation channel complex; GO:0016529 sarcoplasmic reticulum; GO:0012505 endomembrane system; GO:1902495 transmembrane transporter complex; GO:0032541 cortical endoplasmic reticulum; GO:0016021 integral component of membrane; GO:0034704 calcium channel complex; GO:0005886 plasma membrane; GO:0071782 endoplasmic reticulum tubular network; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044432 endoplasmic reticulum part; GO:0044448 cell cortex part; GO:0030176 integral component of endoplasmic reticulum membrane; GO:0031984 organelle subcompartment; GO:0044444 cytoplasmic part; ","GO:0043167 ion binding; GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; GO:0005515 protein binding; GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; GO:0008307 structural constituent of muscle; GO:0016491 oxidoreductase activity; GO:0009055 electron carrier activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0051213 dioxygenase activity; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0044325 ion channel binding; GO:0005509 calcium ion binding; GO:0004597 peptide-aspartate beta-dioxygenase activity; GO:0005198 structural molecule activity; ","K00476",null,null,"IPR007943; IPR007803; IPR027443; IPR011990; IPR013026; ","Aspartyl beta-hydroxylase/Triadin domain; Aspartyl/asparaginy/proline hydroxylase; Isopenicillin N synthase-like; Tetratricopeptide-like helical domain; Tetratricopeptide repeat-containing domain; \r"]
["Q12805","EGF-containing fibulin-like extracellular matrix protein 1 OS=Homo sapiens OX=9606 GN=EFEMP1","EFEMP1",54.64,66.419,20.7,10,18,10,1.228,1.104,1.18,0.816,0.799,0.83,0.696,0.000396,"extracellular\r","GO:0048569 post-embryonic animal organ development; GO:0044700 single organism signaling; GO:0051093 negative regulation of developmental process; GO:0007166 cell surface receptor signaling pathway; GO:0007601 visual perception; GO:0051241 negative regulation of multicellular organismal process; GO:0018212 peptidyl-tyrosine modification; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0050877 neurological system process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0048562 embryonic organ morphogenesis; GO:0007154 cell communication; GO:0038127 ERBB signaling pathway; GO:0048050 post-embryonic eye morphogenesis; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009790 embryo development; GO:0045596 negative regulation of cell differentiation; GO:0048598 embryonic morphogenesis; GO:0090596 sensory organ morphogenesis; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0010468 regulation of gene expression; GO:0007600 sensory perception; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0048592 eye morphogenesis; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0023052 signaling; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0009886 post-embryonic animal morphogenesis; GO:0018108 peptidyl-tyrosine phosphorylation; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0044260 cellular macromolecule metabolic process; GO:0009887 animal organ morphogenesis; GO:0019222 regulation of metabolic process; GO:0006464 cellular protein modification process; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0016310 phosphorylation; GO:0043010 camera-type eye development; GO:0048568 embryonic organ development; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0009791 post-embryonic development; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0007173 epidermal growth factor receptor signaling pathway; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:0071704 organic substance metabolic process; GO:0009653 anatomical structure morphogenesis; GO:0001654 eye development; GO:0006468 protein phosphorylation; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0048048 embryonic eye morphogenesis; GO:0061037 negative regulation of cartilage development; GO:0007275 multicellular organism development; GO:0032330 regulation of chondrocyte differentiation; GO:0009987 cellular process; GO:0061035 regulation of cartilage development; GO:0045595 regulation of cell differentiation; GO:0006355 regulation of transcription, DNA-templated; GO:0003008 system process; GO:0048731 system development; GO:0010556 regulation of macromolecule biosynthetic process; GO:0050953 sensory perception of light stimulus; GO:0044238 primary metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0018193 peptidyl-amino acid modification; GO:0006793 phosphorus metabolic process; GO:0044767 single-organism developmental process; GO:0032331 negative regulation of chondrocyte differentiation; GO:0048563 post-embryonic animal organ morphogenesis; GO:0043412 macromolecule modification; GO:0007423 sensory organ development; GO:0050793 regulation of developmental process; GO:0065007 biological regulation; ","GO:0031012 extracellular matrix; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0005578 proteinaceous extracellular matrix; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:0038023 signaling receptor activity; GO:0008083 growth factor activity; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0005102 receptor binding; GO:0043167 ion binding; GO:0004713 protein tyrosine kinase activity; GO:0070851 growth factor receptor binding; GO:0005515 protein binding; GO:0004672 protein kinase activity; GO:0004888 transmembrane signaling receptor activity; GO:0004871 signal transducer activity; GO:0004714 transmembrane receptor protein tyrosine kinase activity; GO:0019199 transmembrane receptor protein kinase activity; GO:0060089 molecular transducer activity; GO:0016301 kinase activity; GO:0004872 receptor activity; GO:0003824 catalytic activity; GO:0005154 epidermal growth factor receptor binding; GO:0005488 binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005006 epidermal growth factor-activated receptor activity; GO:0005509 calcium ion binding; GO:0016740 transferase activity; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0099600 transmembrane receptor activity; ","K18262",null,null,"IPR026823; IPR001881; IPR000742; IPR009030; ","Complement Clr-like EGF domain; EGF-like calcium-binding domain; EGF-like domain; Growth factor receptor cysteine-rich domain; \r"]
["Q12849","G-rich sequence factor 1 OS=Homo sapiens OX=9606 GN=GRSF1","GRSF1",53.126,3.1671,2.3,1,1,1,0.944,1.04,0.934,1.095,1.026,0.97,1.059,0.305,"mitochondria\r","GO:0031123 RNA 3'-end processing; GO:0002009 morphogenesis of an epithelium; GO:0044707 single-multicellular organism process; GO:0006725 cellular aromatic compound metabolic process; GO:0031124 mRNA 3'-end processing; GO:0006378 mRNA polyadenylation; GO:0007389 pattern specification process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0009653 anatomical structure morphogenesis; GO:0048729 tissue morphogenesis; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0016331 morphogenesis of embryonic epithelium; GO:0043170 macromolecule metabolic process; GO:0007275 multicellular organism development; GO:0009790 embryo development; GO:0009987 cellular process; GO:0048598 embryonic morphogenesis; GO:0034470 ncRNA processing; GO:0032502 developmental process; GO:0009952 anterior/posterior pattern specification; GO:0006396 RNA processing; GO:0060429 epithelium development; GO:0009888 tissue development; GO:0003002 regionalization; GO:0043631 RNA polyadenylation; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:0032501 multicellular organismal process; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:0006399 tRNA metabolic process; GO:0090304 nucleic acid metabolic process; GO:0044767 single-organism developmental process; GO:0008033 tRNA processing; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0034660 ncRNA metabolic process; GO:0048856 anatomical structure development; GO:0016071 mRNA metabolic process; ","GO:0043229 intracellular organelle; GO:0005759 mitochondrial matrix; GO:0042645 mitochondrial nucleoid; GO:0044429 mitochondrial part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0035770 ribonucleoprotein granule; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0009295 nucleoid; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003729 mRNA binding; GO:0003723 RNA binding; GO:1901265 nucleoside phosphate binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0000166 nucleotide binding; GO:0036094 small molecule binding; ",{"$nulls":3},"IPR000504; IPR012677; ","RNA recognition motif domain; Nucleotide-binding alpha-beta plait domain; \r"]
["Q12874","Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3","SF3A3",58.848,30.884,17,8,10,8,0.981,1.03,0.867,1.028,0.976,1.124,1.087,0.27,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0016043 cellular component organization; GO:0006376 mRNA splice site selection; GO:0022613 ribonucleoprotein complex biogenesis; GO:0022618 ribonucleoprotein complex assembly; GO:0006725 cellular aromatic compound metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0008152 metabolic process; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0071826 ribonucleoprotein complex subunit organization; GO:0046483 heterocycle metabolic process; GO:0022607 cellular component assembly; GO:0006139 nucleobase-containing compound metabolic process; GO:0065003 macromolecular complex assembly; GO:0000375 RNA splicing, via transesterification reactions; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0006396 RNA processing; GO:0034622 cellular macromolecular complex assembly; GO:0000389 mRNA 3'-splice site recognition; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0044238 primary metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:0090304 nucleic acid metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0000245 spliceosomal complex assembly; GO:0016071 mRNA metabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005681 spliceosomal complex; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0044464 cell part; GO:0005622 intracellular; GO:0071013 catalytic step 2 spliceosome; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0046914 transition metal ion binding; GO:0005488 binding; GO:0043167 ion binding; GO:0003676 nucleic acid binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0008270 zinc ion binding; ","K12827","SF3A3; splicing factor 3A subunit 3","hsa03040 Spliceosome - Homo sapiens (human); ","IPR021966; IPR000690; IPR031774; IPR024598; ","\"Splicing factor SF3a60 binding domain; Zinc finger, C2H2-type matrin; SF3A3 domain; Domain of unknown function DUF3449; \"\r"]
["Q12904","Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 OS=Homo sapiens OX=9606 GN=AIMP1","AIMP1",34.352,60.173,34.6,7,9,7,0.961,0.967,0.94,1.076,1.053,1.071,1.116,0.000537,"cytoplasm\r","GO:0044700 single organism signaling; GO:0006518 peptide metabolic process; GO:0051674 localization of cell; GO:0001568 blood vessel development; GO:0098542 defense response to other organism; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0009607 response to biotic stimulus; GO:0008285 negative regulation of cell proliferation; GO:0009611 response to wounding; GO:0001937 negative regulation of endothelial cell proliferation; GO:0006006 glucose metabolic process; GO:0009605 response to external stimulus; GO:0022610 biological adhesion; GO:0001525 angiogenesis; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0007154 cell communication; GO:0050678 regulation of epithelial cell proliferation; GO:0006915 apoptotic process; GO:0007155 cell adhesion; GO:0006418 tRNA aminoacylation for protein translation; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0048514 blood vessel morphogenesis; GO:0044419 interspecies interaction between organisms; GO:0006412 translation; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0043043 peptide biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0001944 vasculature development; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0048870 cell motility; GO:0043603 cellular amide metabolic process; GO:0005975 carbohydrate metabolic process; GO:0023052 signaling; GO:0006935 chemotaxis; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0016070 RNA metabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0050900 leukocyte migration; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0007267 cell-cell signaling; GO:0051607 defense response to virus; GO:0090304 nucleic acid metabolic process; GO:0044710 single-organism metabolic process; GO:0006954 inflammatory response; GO:0044260 cellular macromolecule metabolic process; GO:0042330 taxis; GO:0006952 defense response; GO:0040011 locomotion; GO:0006082 organic acid metabolic process; GO:0050680 negative regulation of epithelial cell proliferation; GO:0048856 anatomical structure development; GO:0009615 response to virus; GO:0043436 oxoacid metabolic process; GO:0050794 regulation of cellular process; GO:0072359 circulatory system development; GO:0016477 cell migration; GO:0044707 single-multicellular organism process; GO:0042127 regulation of cell proliferation; GO:0006725 cellular aromatic compound metabolic process; GO:0002252 immune effector process; GO:0044267 cellular protein metabolic process; GO:0043207 response to external biotic stimulus; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:1901566 organonitrogen compound biosynthetic process; GO:0043039 tRNA aminoacylation; GO:0051707 response to other organism; GO:0071704 organic substance metabolic process; GO:0009653 anatomical structure morphogenesis; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0016032 viral process; GO:0005996 monosaccharide metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0001936 regulation of endothelial cell proliferation; GO:0007275 multicellular organism development; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0006950 response to stress; GO:0048731 system development; GO:0006807 nitrogen compound metabolic process; GO:0002376 immune system process; GO:0072358 cardiovascular system development; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0006399 tRNA metabolic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0043038 amino acid activation; GO:0019752 carboxylic acid metabolic process; GO:0006928 movement of cell or subcellular component; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0012501 programmed cell death; GO:0051179 localization; GO:0034660 ncRNA metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0019318 hexose metabolic process; GO:0065007 biological regulation; ","GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0017102 methionyl glutamyl tRNA synthetase complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0017101 aminoacyl-tRNA synthetase multienzyme complex; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:0009986 cell surface; GO:0030133 transport vesicle; GO:0005794 Golgi apparatus; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005125 cytokine activity; GO:0042802 identical protein binding; GO:0000049 tRNA binding; GO:0005102 receptor binding; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0046983 protein dimerization activity; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0051020 GTPase binding; GO:0019899 enzyme binding; ","K15437",null,null,"IPR012340; IPR002547; ","\"Nucleic acid-binding, OB-fold; tRNA-binding domain; \"\r"]
["Q12905","Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2","ILF2",43.062,68.103,26.9,9,19,9,0.942,0.955,0.912,1.089,1.099,1.043,1.15,0.0027,"cytoplasm\r","GO:0045321 leukocyte activation; GO:0097659 nucleic acid-templated transcription; GO:0009891 positive regulation of biosynthetic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0002443 leukocyte mediated immunity; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0002446 neutrophil mediated immunity; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0016070 RNA metabolic process; GO:0006810 transport; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0032940 secretion by cell; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0019222 regulation of metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0043299 leukocyte degranulation; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0002283 neutrophil activation involved in immune response; GO:0006725 cellular aromatic compound metabolic process; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0036230 granulocyte activation; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0051254 positive regulation of RNA metabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0016192 vesicle-mediated transport; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:0043312 neutrophil degranulation; GO:1901576 organic substance biosynthetic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0002263 cell activation involved in immune response; GO:0044249 cellular biosynthetic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0031325 positive regulation of cellular metabolic process; GO:0001775 cell activation; GO:0010467 gene expression; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0006955 immune response; GO:0051179 localization; GO:0006887 exocytosis; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0016020 membrane; GO:1904724 tertiary granule lumen; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0070820 tertiary granule; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0035580 specific granule lumen; GO:0042581 specific granule; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0003677 DNA binding; GO:0003723 RNA binding; GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0003725 double-stranded RNA binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0032550 purine ribonucleoside binding; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K13089",null,null,"IPR006116; IPR006561; ","\"2-5-oligoadenylate synthetase, N-terminal; DZF domain; \"\r"]
["Q12907","Vesicular integral-membrane protein VIP36 OS=Homo sapiens OX=9606 GN=LMAN2","LMAN2",40.228,13.124,13.5,5,10,5,1.002,0.968,0.966,0.983,0.966,1.045,1.02,0.512,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0060627 regulation of vesicle-mediated transport; GO:0030100 regulation of endocytosis; GO:0045807 positive regulation of endocytosis; GO:0051049 regulation of transport; GO:0016192 vesicle-mediated transport; GO:0050766 positive regulation of phagocytosis; GO:0048193 Golgi vesicle transport; GO:0048522 positive regulation of cellular process; GO:0071702 organic substance transport; GO:0048518 positive regulation of biological process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0051050 positive regulation of transport; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:0051130 positive regulation of cellular component organization; GO:0050789 regulation of biological process; GO:0006890 retrograde vesicle-mediated transport, Golgi to ER; GO:0032879 regulation of localization; GO:0051128 regulation of cellular component organization; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0051179 localization; GO:0050764 regulation of phagocytosis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043229 intracellular organelle; GO:0031226 intrinsic component of plasma membrane; GO:0098588 bounding membrane of organelle; GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044459 plasma membrane part; GO:0044432 endoplasmic reticulum part; GO:0005793 endoplasmic reticulum-Golgi intermediate compartment; GO:0009986 cell surface; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0097367 carbohydrate derivative binding; GO:0031072 heat shock protein binding; GO:0005488 binding; GO:0043167 ion binding; GO:0005537 mannose binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0030246 carbohydrate binding; GO:0005515 protein binding; GO:0048029 monosaccharide binding; GO:0001948 glycoprotein binding; GO:0036094 small molecule binding; ","K10082","LMAN2; lectin, mannose-binding 2","hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); ","IPR005052; IPR013320; ","Legume-like lectin; Concanavalin A-like lectin/glucanase domain; \r"]
["Q12955","Ankyrin-3 OS=Homo sapiens OX=9606 GN=ANK3","ANK3",480.4,40.673,3,14,21,11,1.014,1.064,1.024,1.021,0.937,0.977,0.946,0.125,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0071286 cellular response to magnesium ion; GO:0065008 regulation of biological quality; GO:0010960 magnesium ion homeostasis; GO:1903533 regulation of protein targeting; GO:1901017 negative regulation of potassium ion transmembrane transporter activity; GO:0032989 cellular component morphogenesis; GO:0090002 establishment of protein localization to plasma membrane; GO:1904181 positive regulation of membrane depolarization; GO:0050877 neurological system process; GO:0015031 protein transport; GO:0098900 regulation of action potential; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0055065 metal ion homeostasis; GO:0032414 positive regulation of ion transmembrane transporter activity; GO:0051651 maintenance of location in cell; GO:0008104 protein localization; GO:0090314 positive regulation of protein targeting to membrane; GO:0044765 single-organism transport; GO:0007399 nervous system development; GO:0051051 negative regulation of transport; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0032507 maintenance of protein location in cell; GO:0072657 protein localization to membrane; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0043269 regulation of ion transport; GO:2000649 regulation of sodium ion transmembrane transporter activity; GO:0019228 neuronal action potential; GO:0048812 neuron projection morphogenesis; GO:0007009 plasma membrane organization; GO:0032501 multicellular organismal process; GO:0000902 cell morphogenesis; GO:0006810 transport; GO:0034762 regulation of transmembrane transport; GO:2001257 regulation of cation channel activity; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051223 regulation of protein transport; GO:0051301 cell division; GO:0032412 regulation of ion transmembrane transporter activity; GO:0050794 regulation of cellular process; GO:1902260 negative regulation of delayed rectifier potassium channel activity; GO:0044707 single-multicellular organism process; GO:0043267 negative regulation of potassium ion transport; GO:0046907 intracellular transport; GO:0002028 regulation of sodium ion transport; GO:0072661 protein targeting to plasma membrane; GO:0034764 positive regulation of transmembrane transport; GO:0007016 cytoskeletal anchoring at plasma membrane; GO:1901380 negative regulation of potassium ion transmembrane transport; GO:0003254 regulation of membrane depolarization; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0032844 regulation of homeostatic process; GO:1903047 mitotic cell cycle process; GO:1905477 positive regulation of protein localization to membrane; GO:1990778 protein localization to cell periphery; GO:0060341 regulation of cellular localization; GO:0009653 anatomical structure morphogenesis; GO:0000910 cytokinesis; GO:1902578 single-organism localization; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0010628 positive regulation of gene expression; GO:0007409 axonogenesis; GO:0010959 regulation of metal ion transport; GO:1902580 single-organism cellular localization; GO:0032880 regulation of protein localization; GO:0007275 multicellular organism development; GO:0045838 positive regulation of membrane potential; GO:0007010 cytoskeleton organization; GO:0034613 cellular protein localization; GO:0090150 establishment of protein localization to membrane; GO:0048878 chemical homeostasis; GO:0032409 regulation of transporter activity; GO:1904062 regulation of cation transmembrane transport; GO:0034763 negative regulation of transmembrane transport; GO:0019226 transmission of nerve impulse; GO:0045785 positive regulation of cell adhesion; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:1901379 regulation of potassium ion transmembrane transport; GO:0071709 membrane assembly; GO:0071702 organic substance transport; GO:0034110 regulation of homotypic cell-cell adhesion; GO:0044091 membrane biogenesis; GO:0050808 synapse organization; GO:0030155 regulation of cell adhesion; GO:2001259 positive regulation of cation channel activity; GO:0034766 negative regulation of ion transmembrane transport; GO:0045184 establishment of protein localization; GO:0030182 neuron differentiation; GO:0043270 positive regulation of ion transport; GO:1900827 positive regulation of membrane depolarization during cardiac muscle cell action potential; GO:0072659 protein localization to plasma membrane; GO:0061640 cytoskeleton-dependent cytokinesis; GO:1904951 positive regulation of establishment of protein localization; GO:1904064 positive regulation of cation transmembrane transport; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0010650 positive regulation of cell communication by electrical coupling; GO:1902305 regulation of sodium ion transmembrane transport; GO:0006892 post-Golgi vesicle-mediated transport; GO:0051179 localization; GO:0071248 cellular response to metal ion; GO:1900825 regulation of membrane depolarization during cardiac muscle cell action potential; GO:1903827 regulation of cellular protein localization; GO:0090313 regulation of protein targeting to membrane; GO:0007528 neuromuscular junction development; GO:0010256 endomembrane system organization; GO:0032026 response to magnesium ion; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0098901 regulation of cardiac muscle cell action potential; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0043266 regulation of potassium ion transport; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0009893 positive regulation of metabolic process; GO:0032990 cell part morphogenesis; GO:0010765 positive regulation of sodium ion transport; GO:0006893 Golgi to plasma membrane transport; GO:0048858 cell projection morphogenesis; GO:0001508 action potential; GO:2001258 negative regulation of cation channel activity; GO:0010035 response to inorganic substance; GO:0032413 negative regulation of ion transmembrane transporter activity; GO:0033036 macromolecule localization; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0050801 ion homeostasis; GO:0035637 multicellular organismal signaling; GO:0098771 inorganic ion homeostasis; GO:0048522 positive regulation of cellular process; GO:0032386 regulation of intracellular transport; GO:0022898 regulation of transmembrane transporter activity; GO:1902259 regulation of delayed rectifier potassium channel activity; GO:0023052 signaling; GO:0010038 response to metal ion; GO:1902582 single-organism intracellular transport; GO:0042391 regulation of membrane potential; GO:0051050 positive regulation of transport; GO:1902589 single-organism organelle organization; GO:0010649 regulation of cell communication by electrical coupling; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0034767 positive regulation of ion transmembrane transport; GO:0030030 cell projection organization; GO:2000651 positive regulation of sodium ion transmembrane transporter activity; GO:0065009 regulation of molecular function; GO:1901016 regulation of potassium ion transmembrane transporter activity; GO:0071241 cellular response to inorganic substance; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0048856 anatomical structure development; GO:0072507 divalent inorganic cation homeostasis; GO:0051222 positive regulation of protein transport; GO:0016043 cellular component organization; GO:2000021 regulation of ion homeostasis; GO:0090316 positive regulation of intracellular protein transport; GO:0032411 positive regulation of transporter activity; GO:1903829 positive regulation of cellular protein localization; GO:0072660 maintenance of protein location in plasma membrane; GO:0060255 regulation of macromolecule metabolic process; GO:0048193 Golgi vesicle transport; GO:0050896 response to stimulus; GO:0070201 regulation of establishment of protein localization; GO:0048468 cell development; GO:0000904 cell morphogenesis involved in differentiation; GO:0042592 homeostatic process; GO:1905475 regulation of protein localization to membrane; GO:0030154 cell differentiation; GO:0055080 cation homeostasis; GO:0045760 positive regulation of action potential; GO:0032410 negative regulation of transporter activity; GO:0006886 intracellular protein transport; GO:0043001 Golgi to plasma membrane protein transport; GO:0010647 positive regulation of cell communication; GO:0051235 maintenance of location; GO:0033157 regulation of intracellular protein transport; GO:0009987 cellular process; GO:0098902 regulation of membrane depolarization during action potential; GO:0003008 system process; GO:0043271 negative regulation of ion transport; GO:0098876 vesicle-mediated transport to the plasma membrane; GO:0045185 maintenance of protein location; GO:0022409 positive regulation of cell-cell adhesion; GO:0032388 positive regulation of intracellular transport; GO:0051049 regulation of transport; GO:0000281 mitotic cytokinesis; GO:0044802 single-organism membrane organization; GO:0031175 neuron projection development; GO:0048518 positive regulation of biological process; GO:0022407 regulation of cell-cell adhesion; GO:0051641 cellular localization; GO:0061564 axon development; GO:1904063 negative regulation of cation transmembrane transport; GO:1903817 negative regulation of voltage-gated potassium channel activity; GO:0034112 positive regulation of homotypic cell-cell adhesion; GO:0070727 cellular macromolecule localization; GO:0034765 regulation of ion transmembrane transport; GO:0072658 maintenance of protein location in membrane; GO:0044767 single-organism developmental process; GO:0022402 cell cycle process; GO:1902307 positive regulation of sodium ion transmembrane transport; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0030425 dendrite; GO:0005737 cytoplasm; GO:0016528 sarcoplasm; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0031674 I band; GO:0014704 intercalated disc; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0030315 T-tubule; GO:0098590 plasma membrane region; GO:0005622 intracellular; GO:0005764 lysosome; GO:0097060 synaptic membrane; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0000323 lytic vacuole; GO:0042995 cell projection; GO:0043194 axon initial segment; GO:0016328 lateral plasma membrane; GO:0033267 axon part; GO:0005886 plasma membrane; GO:0099081 supramolecular polymer; GO:0030424 axon; GO:0043231 intracellular membrane-bounded organelle; GO:0098794 postsynapse; GO:0043034 costamere; GO:0005773 vacuole; GO:0044449 contractile fiber part; GO:0014731 spectrin-associated cytoskeleton; GO:0042383 sarcolemma; GO:0033268 node of Ranvier; GO:0016323 basolateral plasma membrane; GO:0005783 endoplasmic reticulum; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0044291 cell-cell contact zone; GO:0030016 myofibril; GO:0044424 intracellular part; GO:0099512 supramolecular fiber; GO:0030018 Z disc; GO:0005911 cell-cell junction; GO:0005856 cytoskeleton; GO:0044425 membrane part; GO:0044464 cell part; GO:0044304 main axon; GO:0043292 contractile fiber; GO:0044456 synapse part; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0031594 neuromuscular junction; GO:0016529 sarcoplasmic reticulum; GO:0012505 endomembrane system; GO:0044463 cell projection part; GO:0005829 cytosol; GO:0045202 synapse; GO:0045211 postsynaptic membrane; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0044459 plasma membrane part; GO:0030017 sarcomere; GO:0009986 cell surface; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:0050839 cell adhesion molecule binding; GO:0030674 protein binding, bridging; GO:0008092 cytoskeletal protein binding; GO:0005200 structural constituent of cytoskeleton; GO:0005488 binding; GO:0045296 cadherin binding; GO:0044325 ion channel binding; GO:0005515 protein binding; GO:0060090 binding, bridging; GO:0005198 structural molecule activity; GO:0030507 spectrin binding; ","K10380","ANK; ankyrin","hsa05205 Proteoglycans in cancer - Homo sapiens (human); ","IPR000488; IPR000906; IPR020683; IPR011029; ","Death domain; ZU5 domain; Ankyrin repeat-containing domain; Death-like domain; \r"]
["Q12979","Active breakpoint cluster region-related protein OS=Homo sapiens OX=9606 GN=ABR","ABR",97.597,9.2243,5.1,4,4,4,0.946,1.134,1.055,1.023,0.91,0.949,0.919,0.259,"cytoplasm\r","GO:0060627 regulation of vesicle-mediated transport; GO:0044700 single organism signaling; GO:0002694 regulation of leukocyte activation; GO:0010941 regulation of cell death; GO:0065008 regulation of biological quality; GO:0007420 brain development; GO:0002698 negative regulation of immune effector process; GO:1903306 negative regulation of regulated secretory pathway; GO:1902563 regulation of neutrophil activation; GO:0031347 regulation of defense response; GO:0050877 neurological system process; GO:0009607 response to biotic stimulus; GO:0009605 response to external stimulus; GO:0030036 actin cytoskeleton organization; GO:0060313 negative regulation of blood vessel remodeling; GO:0048562 embryonic organ morphogenesis; GO:0032879 regulation of localization; GO:0032102 negative regulation of response to external stimulus; GO:0044093 positive regulation of molecular function; GO:0009790 embryo development; GO:0051056 regulation of small GTPase mediated signal transduction; GO:0048598 embryonic morphogenesis; GO:0090596 sensory organ morphogenesis; GO:0002887 negative regulation of myeloid leukocyte mediated immunity; GO:0051051 negative regulation of transport; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0043114 regulation of vascular permeability; GO:1903531 negative regulation of secretion by cell; GO:0044763 single-organism cellular process; GO:0007264 small GTPase mediated signal transduction; GO:2000146 negative regulation of cell motility; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0048513 animal organ development; GO:0043583 ear development; GO:0051336 regulation of hydrolase activity; GO:0007417 central nervous system development; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0009887 animal organ morphogenesis; GO:0002682 regulation of immune system process; GO:0002685 regulation of leukocyte migration; GO:0003013 circulatory system process; GO:0043068 positive regulation of programmed cell death; GO:0050794 regulation of cellular process; GO:0045920 negative regulation of exocytosis; GO:0044707 single-multicellular organism process; GO:0050728 negative regulation of inflammatory response; GO:0043067 regulation of programmed cell death; GO:1901700 response to oxygen-containing compound; GO:0017157 regulation of exocytosis; GO:0003018 vascular process in circulatory system; GO:0002886 regulation of myeloid leukocyte mediated immunity; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0080134 regulation of response to stress; GO:0051239 regulation of multicellular organismal process; GO:0050866 negative regulation of cell activation; GO:0009653 anatomical structure morphogenesis; GO:0051345 positive regulation of hydrolase activity; GO:2000145 regulation of cell motility; GO:0043300 regulation of leukocyte degranulation; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0009966 regulation of signal transduction; GO:0050885 neuromuscular process controlling balance; GO:0009617 response to bacterium; GO:1902531 regulation of intracellular signal transduction; GO:0030100 regulation of endocytosis; GO:0051270 regulation of cellular component movement; GO:0032496 response to lipopolysaccharide; GO:0043547 positive regulation of GTPase activity; GO:0048731 system development; GO:0034104 negative regulation of tissue remodeling; GO:0050766 positive regulation of phagocytosis; GO:0030334 regulation of cell migration; GO:0032101 regulation of response to external stimulus; GO:0010033 response to organic substance; GO:0048839 inner ear development; GO:0043301 negative regulation of leukocyte degranulation; GO:0002691 regulation of cellular extravasation; GO:0030336 negative regulation of cell migration; GO:0006996 organelle organization; GO:0060312 regulation of blood vessel remodeling; GO:0030029 actin filament-based process; GO:0007423 sensory organ development; GO:0035023 regulation of Rho protein signal transduction; GO:0050905 neuromuscular process; GO:0050793 regulation of developmental process; GO:0043314 negative regulation of neutrophil degranulation; GO:0051093 negative regulation of developmental process; GO:0023051 regulation of signaling; GO:0051046 regulation of secretion; GO:0044699 single-organism process; GO:0051241 negative regulation of multicellular organismal process; GO:0042472 inner ear morphogenesis; GO:0034103 regulation of tissue remodeling; GO:0051130 positive regulation of cellular component organization; GO:0040013 negative regulation of locomotion; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:1902564 negative regulation of neutrophil activation; GO:0050777 negative regulation of immune response; GO:0060322 head development; GO:0002695 negative regulation of leukocyte activation; GO:0002697 regulation of immune effector process; GO:0050764 regulation of phagocytosis; GO:0032502 developmental process; GO:0002237 response to molecule of bacterial origin; GO:0048522 positive regulation of cellular process; GO:1903530 regulation of secretion by cell; GO:0023052 signaling; GO:0051050 positive regulation of transport; GO:0010942 positive regulation of cell death; GO:0002683 negative regulation of immune system process; GO:1902589 single-organism organelle organization; GO:0051048 negative regulation of secretion; GO:0050865 regulation of cell activation; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0043087 regulation of GTPase activity; GO:0065009 regulation of molecular function; GO:0048856 anatomical structure development; GO:0051271 negative regulation of cellular component movement; GO:0002686 negative regulation of leukocyte migration; GO:0016043 cellular component organization; GO:0045807 positive regulation of endocytosis; GO:0048568 embryonic organ development; GO:0002704 negative regulation of leukocyte mediated immunity; GO:0043065 positive regulation of apoptotic process; GO:0046578 regulation of Ras protein signal transduction; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0033993 response to lipid; GO:0008015 blood circulation; GO:0009987 cellular process; GO:0002692 negative regulation of cellular extravasation; GO:0031348 negative regulation of defense response; GO:0003008 system process; GO:0035556 intracellular signal transduction; GO:0051049 regulation of transport; GO:0048585 negative regulation of response to stimulus; GO:1903305 regulation of regulated secretory pathway; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0002703 regulation of leukocyte mediated immunity; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0050727 regulation of inflammatory response; GO:0042471 ear morphogenesis; GO:0051128 regulation of cellular component organization; GO:0040012 regulation of locomotion; GO:0043313 regulation of neutrophil degranulation; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0071944 cell periphery; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005886 plasma membrane; GO:0044444 cytoplasmic part; ","GO:0030234 enzyme regulator activity; GO:0005085 guanyl-nucleotide exchange factor activity; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0005488 binding; GO:0030695 GTPase regulator activity; GO:0005088 Ras guanyl-nucleotide exchange factor activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0008047 enzyme activator activity; GO:0005089 Rho guanyl-nucleotide exchange factor activity; GO:0005096 GTPase activator activity; ","K20629",null,null,"IPR011993; IPR000219; IPR008936; IPR000008; IPR000198; IPR001849; ","PH domain-like; Dbl homology (DH) domain; Rho GTPase activation protein; C2 domain; Rho GTPase-activating protein domain; Pleckstrin homology domain; \r"]
["Q13033","Striatin-3 OS=Homo sapiens OX=9606 GN=STRN3","STRN3",87.208,1.8345,2.1,2,3,1,1.079,1.059,1.02,0.98,0.995,0.884,0.905,0.0688,"nucleus\r","GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0009891 positive regulation of biosynthetic process; GO:0051253 negative regulation of RNA metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0010646 regulation of cell communication; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0014070 response to organic cyclic compound; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0000122 negative regulation of transcription from RNA polymerase II promoter; GO:0048522 positive regulation of cellular process; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0048583 regulation of response to stimulus; GO:1902679 negative regulation of RNA biosynthetic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0033143 regulation of intracellular steroid hormone receptor signaling pathway; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:1901700 response to oxygen-containing compound; GO:0032355 response to estradiol; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0048523 negative regulation of cellular process; GO:0033144 negative regulation of intracellular steroid hormone receptor signaling pathway; GO:0050896 response to stimulus; GO:0045892 negative regulation of transcription, DNA-templated; GO:0033993 response to lipid; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0009966 regulation of signal transduction; GO:0051254 positive regulation of RNA metabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0010033 response to organic substance; GO:0048585 negative regulation of response to stimulus; GO:0048518 positive regulation of biological process; GO:0009892 negative regulation of metabolic process; GO:0051252 regulation of RNA metabolic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway; GO:0009890 negative regulation of biosynthetic process; GO:0033146 regulation of intracellular estrogen receptor signaling pathway; GO:0031325 positive regulation of cellular metabolic process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0030425 dendrite; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0043025 neuronal cell body; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0005634 nucleus; GO:0044297 cell body; GO:0043234 protein complex; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0070016 armadillo repeat domain binding; GO:0019903 protein phosphatase binding; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0001071 nucleic acid binding transcription factor activity; GO:0019904 protein domain specific binding; GO:0005515 protein binding; GO:0019902 phosphatase binding; GO:0005516 calmodulin binding; GO:0003700 transcription factor activity, sequence-specific DNA binding; GO:0051721 protein phosphatase 2A binding; GO:0019899 enzyme binding; GO:0032403 protein complex binding; ","K17608",null,null,"IPR017986; IPR013258; IPR015943; ","\"WD40-repeat-containing domain; Striatin, N-terminal; WD40/YVTN repeat-like-containing domain; \"\r"]
["Q13045","Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII","FLII",144.75,16.852,4.7,6,7,6,1.011,0.978,0.904,1.03,1.042,1.016,1.067,0.123,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0097659 nucleic acid-templated transcription; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0030036 actin cytoskeleton organization; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0043170 macromolecule metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0051014 actin filament severing; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0006355 regulation of transcription, DNA-templated; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:1901576 organic substance biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0016070 RNA metabolic process; GO:1902589 single-organism organelle organization; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0034645 cellular macromolecule biosynthetic process; GO:0090304 nucleic acid metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006351 transcription, DNA-templated; GO:0044767 single-organism developmental process; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0010467 gene expression; GO:0048856 anatomical structure development; GO:1901362 organic cyclic compound biosynthetic process; GO:0071840 cellular component organization or biogenesis; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0065007 biological regulation; ","GO:0098862 cluster of actin-based cell projections; GO:0005903 brush border; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0005654 nucleoplasm; GO:0005815 microtubule organizing center; GO:0005925 focal adhesion; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0003779 actin binding; GO:0005515 protein binding; GO:0008092 cytoskeletal protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR032675; IPR029006; IPR007123; ","\"Leucine-rich repeat domain, L domain-like; ADF-H/Gelsolin-like domain; Gelsolin-like domain; \"\r"]
["Q13085","Acetyl-CoA carboxylase 1 OS=Homo sapiens OX=9606 GN=ACACA","ACACA",265.55,28.784,4.7,10,11,10,1.185,1.092,1.192,0.825,0.856,0.851,0.73,0.000501,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0035337 fatty-acyl-CoA metabolic process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0044272 sulfur compound biosynthetic process; GO:0008610 lipid biosynthetic process; GO:0008152 metabolic process; GO:0015718 monocarboxylic acid transport; GO:0065003 macromolecular complex assembly; GO:0009719 response to endogenous stimulus; GO:0032787 monocarboxylic acid metabolic process; GO:0009108 coenzyme biosynthetic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0055088 lipid homeostasis; GO:0044259 multicellular organismal macromolecule metabolic process; GO:0044765 single-organism transport; GO:0006790 sulfur compound metabolic process; GO:0051716 cellular response to stimulus; GO:0006869 lipid transport; GO:0071398 cellular response to fatty acid; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006732 coenzyme metabolic process; GO:0006084 acetyl-CoA metabolic process; GO:0046942 carboxylic acid transport; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0071396 cellular response to lipid; GO:0006810 transport; GO:0044710 single-organism metabolic process; GO:0043436 oxoacid metabolic process; GO:0006853 carnitine shuttle; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0044707 single-multicellular organism process; GO:0034220 ion transmembrane transport; GO:0044268 multicellular organismal protein metabolic process; GO:0051260 protein homooligomerization; GO:1901700 response to oxygen-containing compound; GO:2001295 malonyl-CoA biosynthetic process; GO:0060249 anatomical structure homeostasis; GO:0051259 protein oligomerization; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:1903825 organic acid transmembrane transport; GO:0071229 cellular response to acid chemical; GO:1902580 single-organism cellular localization; GO:0070542 response to fatty acid; GO:0048878 chemical homeostasis; GO:0006461 protein complex assembly; GO:0006767 water-soluble vitamin metabolic process; GO:2001293 malonyl-CoA metabolic process; GO:1901655 cellular response to ketone; GO:0044711 single-organism biosynthetic process; GO:0034694 response to prostaglandin; GO:0035383 thioester metabolic process; GO:0010876 lipid localization; GO:0071702 organic substance transport; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0015849 organic acid transport; GO:1901576 organic substance biosynthetic process; GO:0015909 long-chain fatty acid transport; GO:0055085 transmembrane transport; GO:0006793 phosphorus metabolic process; GO:0006811 ion transport; GO:0031325 positive regulation of cellular metabolic process; GO:0044283 small molecule biosynthetic process; GO:0051179 localization; GO:0072330 monocarboxylic acid biosynthetic process; GO:0071379 cellular response to prostaglandin stimulus; GO:1901564 organonitrogen compound metabolic process; GO:0051188 cofactor biosynthetic process; GO:0001101 response to acid chemical; GO:0016053 organic acid biosynthetic process; GO:0034695 response to prostaglandin E; GO:0006839 mitochondrial transport; GO:0044236 multicellular organism metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0035384 thioester biosynthetic process; GO:0048871 multicellular organismal homeostasis; GO:0051234 establishment of localization; GO:0051649 establishment of localization in cell; GO:0032365 intracellular lipid transport; GO:0051262 protein tetramerization; GO:0022607 cellular component assembly; GO:0009893 positive regulation of metabolic process; GO:0033036 macromolecule localization; GO:0070887 cellular response to chemical stimulus; GO:0006629 lipid metabolic process; GO:1905039 carboxylic acid transmembrane transport; GO:0071822 protein complex subunit organization; GO:0071616 acyl-CoA biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0035336 long-chain fatty-acyl-CoA metabolic process; GO:0043603 cellular amide metabolic process; GO:0035338 long-chain fatty-acyl-CoA biosynthetic process; GO:0006633 fatty acid biosynthetic process; GO:1902582 single-organism intracellular transport; GO:0051186 cofactor metabolic process; GO:0046394 carboxylic acid biosynthetic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0032870 cellular response to hormone stimulus; GO:0001894 tissue homeostasis; GO:0019222 regulation of metabolic process; GO:0006082 organic acid metabolic process; GO:0070271 protein complex biogenesis; GO:0016043 cellular component organization; GO:0046949 fatty-acyl-CoA biosynthetic process; GO:0071310 cellular response to organic substance; GO:0006768 biotin metabolic process; GO:0050896 response to stimulus; GO:0098656 anion transmembrane transport; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0033993 response to lipid; GO:0051289 protein homotetramerization; GO:0006766 vitamin metabolic process; GO:0015908 fatty acid transport; GO:1990542 mitochondrial transmembrane transport; GO:0034641 cellular nitrogen compound metabolic process; GO:0071380 cellular response to prostaglandin E stimulus; GO:0009987 cellular process; GO:1902001 fatty acid transmembrane transport; GO:0006807 nitrogen compound metabolic process; GO:0006631 fatty acid metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0006637 acyl-CoA metabolic process; GO:0051641 cellular localization; GO:0043933 macromolecular complex subunit organization; GO:0006820 anion transport; GO:0015711 organic anion transport; GO:1901701 cellular response to oxygen-containing compound; GO:0071495 cellular response to endogenous stimulus; GO:0019752 carboxylic acid metabolic process; GO:0009725 response to hormone; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:1901654 response to ketone; ","GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044452 nucleolar part; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0015629 actin cytoskeleton; GO:0001650 fibrillar center; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0016885 ligase activity, forming carbon-carbon bonds; GO:0016874 ligase activity; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0016879 ligase activity, forming carbon-nitrogen bonds; GO:0003989 acetyl-CoA carboxylase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0004075 biotin carboxylase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016421 CoA carboxylase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K11262","ACACA; acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15]","hsa00061 Fatty acid biosynthesis - Homo sapiens (human); hsa00640 Propanoate metabolism - Homo sapiens (human); hsa00620 Pyruvate metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa01212 Fatty acid metabolism - Homo sapiens (human); hsa04922 Glucagon signaling pathway - Homo sapiens (human); hsa04910 Insulin signaling pathway - Homo sapiens (human); hsa04152 AMPK signaling pathway - Homo sapiens (human); ","IPR011762; IPR029045; IPR000022; IPR005481; IPR000089; IPR016185; IPR005482; IPR011761; IPR011053; IPR005479; IPR013815; IPR013537; IPR011764; IPR013816; IPR011763; IPR011054; ","\"Acetyl-coenzyme A carboxyltransferase, N-terminal; ClpP/crotonase-like domain; Carboxyl transferase; Biotin carboxylase-like, N-terminal domain; Biotin/lipoyl attachment; Pre-ATP-grasp domain; Biotin carboxylase, C-terminal; ATP-grasp fold; Single hybrid motif; Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain; ATP-grasp fold, subdomain 1; Acetyl-CoA carboxylase, central domain; Biotin carboxylation domain; ATP-grasp fold, subdomain 2; Acetyl-coenzyme A carboxyltransferase, C-terminal; Rudiment single hybrid motif; \"\r"]
["Q13123","Protein Red OS=Homo sapiens OX=9606 GN=IK","IK",65.601,4.6993,3.4,2,3,2,0.819,0.884,1.035,1.132,1.094,1.03,1.189,0.0753,"nucleus\r","GO:0044700 single organism signaling; GO:0007267 cell-cell signaling; GO:0007154 cell communication; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0002376 immune system process; GO:0006955 immune response; GO:0023052 signaling; GO:0050896 response to stimulus; GO:0009987 cellular process; ","GO:0043229 intracellular organelle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0042802 identical protein binding; GO:0005488 binding; ","K13109",null,null,"IPR012916; IPR012492; ","\"RED-like, N-terminal; Protein RED, C-terminal; \"\r"]
["Q13126","S-methyl-5'-thioadenosine phosphorylase OS=Homo sapiens OX=9606 GN=MTAP","MTAP",31.236,40.741,26.5,6,6,6,1.061,1.033,1.01,0.922,0.966,0.934,0.909,0.00874,"cytoskeleton\r","GO:0042278 purine nucleoside metabolic process; GO:0009116 nucleoside metabolic process; GO:0000097 sulfur amino acid biosynthetic process; GO:0016053 organic acid biosynthetic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0009163 nucleoside biosynthetic process; GO:0046129 purine ribonucleoside biosynthetic process; GO:0043174 nucleoside salvage; GO:0044237 cellular metabolic process; GO:0000096 sulfur amino acid metabolic process; GO:0044272 sulfur compound biosynthetic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:1901607 alpha-amino acid biosynthetic process; GO:0043102 amino acid salvage; GO:0006555 methionine metabolic process; GO:0006790 sulfur compound metabolic process; GO:0018130 heterocycle biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0072521 purine-containing compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0042451 purine nucleoside biosynthetic process; GO:0046394 carboxylic acid biosynthetic process; GO:0072522 purine-containing compound biosynthetic process; GO:0043094 cellular metabolic compound salvage; GO:0044710 single-organism metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0006082 organic acid metabolic process; GO:0043436 oxoacid metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0019509 L-methionine salvage from methylthioadenosine; GO:0009066 aspartate family amino acid metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0009086 methionine biosynthetic process; GO:0071265 L-methionine biosynthetic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0009119 ribonucleoside metabolic process; GO:0009067 aspartate family amino acid biosynthetic process; GO:0008652 cellular amino acid biosynthetic process; GO:0044711 single-organism biosynthetic process; GO:0006166 purine ribonucleoside salvage; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:0042455 ribonucleoside biosynthetic process; GO:1901605 alpha-amino acid metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0046128 purine ribonucleoside metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:1901659 glycosyl compound biosynthetic process; GO:0019752 carboxylic acid metabolic process; GO:0044283 small molecule biosynthetic process; GO:0071267 L-methionine salvage; GO:0043101 purine-containing compound salvage; GO:1901564 organonitrogen compound metabolic process; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016763 transferase activity, transferring pentosyl groups; GO:0017061 S-methyl-5-thioadenosine phosphorylase activity; GO:0016758 transferase activity, transferring hexosyl groups; GO:0003824 catalytic activity; GO:0005488 binding; GO:0004645 phosphorylase activity; GO:0004731 purine-nucleoside phosphorylase activity; GO:0016757 transferase activity, transferring glycosyl groups; GO:0005515 protein binding; GO:0016740 transferase activity; ","K00772","mtaP; 5'-methylthioadenosine phosphorylase [EC:2.4.2.28]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00270 Cysteine and methionine metabolism - Homo sapiens (human); ","IPR000845; ","Nucleoside phosphorylase domain; \r"]
["Q13148","TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP","TARDBP",44.739,20.218,9.7,5,11,5,0.978,0.963,0.958,1.017,1.032,1.055,1.071,0.00522,"nucleus\r","GO:0065008 regulation of biological quality; GO:0097659 nucleic acid-templated transcription; GO:0010608 posttranscriptional regulation of gene expression; GO:0043489 RNA stabilization; GO:0050796 regulation of insulin secretion; GO:0009891 positive regulation of biosynthetic process; GO:0002793 positive regulation of peptide secretion; GO:0044237 cellular metabolic process; GO:0032897 negative regulation of viral transcription; GO:0008152 metabolic process; GO:0032879 regulation of localization; GO:0071763 nuclear membrane organization; GO:0043170 macromolecule metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0044419 interspecies interaction between organisms; GO:0006396 RNA processing; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0051174 regulation of phosphorus metabolic process; GO:0018130 heterocycle biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044763 single-organism cellular process; GO:0032774 RNA biosynthetic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0031323 regulation of cellular metabolic process; GO:0051704 multi-organism process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0046883 regulation of hormone secretion; GO:0071765 nuclear inner membrane organization; GO:0032269 negative regulation of cellular protein metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0050714 positive regulation of protein secretion; GO:0010604 positive regulation of macromolecule metabolic process; GO:0010817 regulation of hormone levels; GO:0097194 execution phase of apoptosis; GO:0051223 regulation of protein transport; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0048255 mRNA stabilization; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0051047 positive regulation of secretion; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0034976 response to endoplasmic reticulum stress; GO:0031399 regulation of protein modification process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0090277 positive regulation of peptide hormone secretion; GO:1903901 negative regulation of viral life cycle; GO:0051817 modification of morphology or physiology of other organism involved in symbiotic interaction; GO:0043487 regulation of RNA stability; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0001933 negative regulation of protein phosphorylation; GO:0051702 interaction with symbiont; GO:0032880 regulation of protein localization; GO:0008380 RNA splicing; GO:0090087 regulation of peptide transport; GO:0051254 positive regulation of RNA metabolic process; GO:0070935 3'-UTR-mediated mRNA stabilization; GO:0006950 response to stress; GO:0043900 regulation of multi-organism process; GO:0052472 modulation by host of symbiont transcription; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0030264 nuclear fragmentation involved in apoptotic nuclear change; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0009890 negative regulation of biosynthetic process; GO:0046782 regulation of viral transcription; GO:1904951 positive regulation of establishment of protein localization; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0061024 membrane organization; GO:0046887 positive regulation of hormone secretion; GO:0012501 programmed cell death; GO:0031328 positive regulation of cellular biosynthetic process; GO:0045936 negative regulation of phosphate metabolic process; GO:0010256 endomembrane system organization; GO:0023051 regulation of signaling; GO:0051046 regulation of secretion; GO:0052312 modulation of transcription in other organism involved in symbiotic interaction; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0035821 modification of morphology or physiology of other organism; GO:0051253 negative regulation of RNA metabolic process; GO:0031400 negative regulation of protein modification process; GO:2001141 regulation of RNA biosynthetic process; GO:0010646 regulation of cell communication; GO:0009893 positive regulation of metabolic process; GO:0030262 apoptotic nuclear changes; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0006915 apoptotic process; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0051726 regulation of cell cycle; GO:0048525 negative regulation of viral process; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0043921 modulation by host of viral transcription; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:1903530 regulation of secretion by cell; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051050 positive regulation of transport; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:1903532 positive regulation of secretion by cell; GO:1902679 negative regulation of RNA biosynthetic process; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0051222 positive regulation of protein transport; GO:0051851 modification by host of symbiont morphology or physiology; GO:0006997 nucleus organization; GO:0016043 cellular component organization; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0043922 negative regulation by host of viral transcription; GO:0070201 regulation of establishment of protein localization; GO:0006998 nuclear envelope organization; GO:0071704 organic substance metabolic process; GO:0002791 regulation of peptide secretion; GO:0042326 negative regulation of phosphorylation; GO:0023056 positive regulation of signaling; GO:0034641 cellular nitrogen compound metabolic process; GO:0010647 positive regulation of cell communication; GO:0009059 macromolecule biosynthetic process; GO:0050708 regulation of protein secretion; GO:0009987 cellular process; GO:0032024 positive regulation of insulin secretion; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0051049 regulation of transport; GO:0001932 regulation of protein phosphorylation; GO:0050792 regulation of viral process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0044802 single-organism membrane organization; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0006921 cellular component disassembly involved in execution phase of apoptosis; GO:0051252 regulation of RNA metabolic process; GO:0043488 regulation of mRNA stability; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0043901 negative regulation of multi-organism process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0008219 cell death; GO:0051246 regulation of protein metabolic process; GO:0010563 negative regulation of phosphorus metabolic process; GO:0006366 transcription from RNA polymerase II promoter; GO:0090276 regulation of peptide hormone secretion; GO:0051248 negative regulation of protein metabolic process; GO:0022411 cellular component disassembly; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0010467 gene expression; GO:0031327 negative regulation of cellular biosynthetic process; GO:1903900 regulation of viral life cycle; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044454 nuclear chromosome part; GO:0016607 nuclear speck; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0000790 nuclear chromatin; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0035061 interchromatin granule; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0000785 chromatin; GO:0000228 nuclear chromosome; GO:0005726 perichromatin fibrils; GO:0044428 nuclear part; ","GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding; GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding; GO:0003677 DNA binding; GO:0003723 RNA binding; GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding; GO:1901265 nucleoside phosphate binding; GO:0003690 double-stranded DNA binding; GO:0003730 mRNA 3'-UTR binding; GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0003700 transcription factor activity, sequence-specific DNA binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0003729 mRNA binding; GO:0042802 identical protein binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0001071 nucleic acid binding transcription factor activity; GO:0036094 small molecule binding; ",{"$nulls":3},"IPR000504; IPR012677; ","RNA recognition motif domain; Nucleotide-binding alpha-beta plait domain; \r"]
["Q13162","Peroxiredoxin-4 OS=Homo sapiens OX=9606 GN=PRDX4","PRDX4",30.54,39.554,28.8,6,16,4,1.167,1.137,1.129,0.865,0.844,0.864,0.749,2.17e-05,"extracellular\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0022414 reproductive process; GO:0008584 male gonad development; GO:0044237 cellular metabolic process; GO:0008285 negative regulation of cell proliferation; GO:0008152 metabolic process; GO:0044702 single organism reproductive process; GO:0098869 cellular oxidant detoxification; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0003006 developmental process involved in reproduction; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0019953 sexual reproduction; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0048513 animal organ development; GO:0044710 single-organism metabolic process; GO:2000242 negative regulation of reproductive process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0048609 multicellular organismal reproductive process; GO:0043436 oxoacid metabolic process; GO:0050794 regulation of cellular process; GO:0000003 reproduction; GO:0016310 phosphorylation; GO:0044707 single-multicellular organism process; GO:0002283 neutrophil activation involved in immune response; GO:0042127 regulation of cell proliferation; GO:0045454 cell redox homeostasis; GO:0044267 cellular protein metabolic process; GO:0008406 gonad development; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0051239 regulation of multicellular organismal process; GO:1905937 negative regulation of germ cell proliferation; GO:1990748 cellular detoxification; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0043062 extracellular structure organization; GO:0007548 sex differentiation; GO:0007275 multicellular organism development; GO:0061458 reproductive system development; GO:2000254 regulation of male germ cell proliferation; GO:0007283 spermatogenesis; GO:0048731 system development; GO:0043900 regulation of multi-organism process; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:1901605 alpha-amino acid metabolic process; GO:0044238 primary metabolic process; GO:0002263 cell activation involved in immune response; GO:0045055 regulated exocytosis; GO:0006793 phosphorus metabolic process; GO:2000255 negative regulation of male germ cell proliferation; GO:0001775 cell activation; GO:0007249 I-kappaB kinase/NF-kappaB signaling; GO:0046546 development of primary male sexual characteristics; GO:0051179 localization; GO:0006955 immune response; GO:0043412 macromolecule modification; GO:1901564 organonitrogen compound metabolic process; GO:0006887 exocytosis; GO:0044699 single-organism process; GO:0051241 negative regulation of multicellular organismal process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0006457 protein folding; GO:0007165 signal transduction; GO:0006520 cellular amino acid metabolic process; GO:0007154 cell communication; GO:0019471 4-hydroxyproline metabolic process; GO:0030198 extracellular matrix organization; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:0007252 I-kappaB phosphorylation; GO:0055114 oxidation-reduction process; GO:0002446 neutrophil mediated immunity; GO:0009636 response to toxic substance; GO:0048608 reproductive structure development; GO:0019725 cellular homeostasis; GO:0023052 signaling; GO:0002444 myeloid leukocyte mediated immunity; GO:2000241 regulation of reproductive process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0032940 secretion by cell; GO:0043299 leukocyte degranulation; GO:0036211 protein modification process; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:0098754 detoxification; GO:0016043 cellular component organization; GO:0002252 immune effector process; GO:0046661 male sex differentiation; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0006468 protein phosphorylation; GO:0006575 cellular modified amino acid metabolic process; GO:0072593 reactive oxygen species metabolic process; GO:1905936 regulation of germ cell proliferation; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0045137 development of primary sexual characteristics; GO:0048232 male gamete generation; GO:0035556 intracellular signal transduction; GO:0022417 protein maturation by protein folding; GO:0006807 nitrogen compound metabolic process; GO:0043312 neutrophil degranulation; GO:0007276 gamete generation; GO:0043901 negative regulation of multi-organism process; GO:0032504 multicellular organism reproduction; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0044767 single-organism developmental process; GO:0044703 multi-organism reproductive process; GO:0019752 carboxylic acid metabolic process; GO:0010467 gene expression; GO:0051604 protein maturation; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0005790 smooth endoplasmic reticulum; GO:0034774 secretory granule lumen; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0008379 thioredoxin peroxidase activity; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0051920 peroxiredoxin activity; GO:0046983 protein dimerization activity; GO:0016209 antioxidant activity; GO:0005515 protein binding; GO:0004601 peroxidase activity; GO:0016684 oxidoreductase activity, acting on peroxide as acceptor; GO:0016491 oxidoreductase activity; ","K03386",null,null,"IPR019479; IPR000866; IPR013766; IPR012336; ","\"Peroxiredoxin, C-terminal; Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant; Thioredoxin domain; Thioredoxin-like fold; \"\r"]
["Q13185","Chromobox protein homolog 3 OS=Homo sapiens OX=9606 GN=CBX3","CBX3",20.811,50.251,39.9,6,11,5,0.931,0.944,0.884,1.114,1.071,1.067,1.179,2.48E-3,"nucleus\r","GO:0097659 nucleic acid-templated transcription; GO:0071384 cellular response to corticosteroid stimulus; GO:0009058 biosynthetic process; GO:0071383 cellular response to steroid hormone stimulus; GO:0044237 cellular metabolic process; GO:0051253 negative regulation of RNA metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0071549 cellular response to dexamethasone stimulus; GO:0048545 response to steroid hormone; GO:0009719 response to endogenous stimulus; GO:0043170 macromolecule metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0070887 cellular response to chemical stimulus; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051384 response to glucocorticoid; GO:0071396 cellular response to lipid; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0032870 cellular response to hormone stimulus; GO:1902679 negative regulation of RNA biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0006325 chromatin organization; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0006338 chromatin remodeling; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:1901700 response to oxygen-containing compound; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0045892 negative regulation of transcription, DNA-templated; GO:0033993 response to lipid; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0031960 response to corticosteroid; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0016569 covalent chromatin modification; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:1901655 cellular response to ketone; GO:0006355 regulation of transcription, DNA-templated; GO:0071385 cellular response to glucocorticoid stimulus; GO:0010629 negative regulation of gene expression; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0071407 cellular response to organic cyclic compound; GO:0010556 regulation of macromolecule biosynthetic process; GO:0010033 response to organic substance; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0044238 primary metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0071548 response to dexamethasone; GO:0009890 negative regulation of biosynthetic process; GO:1901701 cellular response to oxygen-containing compound; GO:0051276 chromosome organization; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0071495 cellular response to endogenous stimulus; GO:0048511 rhythmic process; GO:0006996 organelle organization; GO:0010467 gene expression; GO:0031327 negative regulation of cellular biosynthetic process; GO:0043412 macromolecule modification; GO:0009725 response to hormone; GO:1901654 response to ketone; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0000784 nuclear chromosome, telomeric region; GO:0000781 chromosome, telomeric region; GO:0031090 organelle membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0000792 heterochromatin; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0000793 condensed chromosome; GO:0031974 membrane-enclosed lumen; GO:0031965 nuclear membrane; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0044454 nuclear chromosome part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0019866 organelle inner membrane; GO:0000790 nuclear chromatin; GO:0005721 pericentric heterochromatin; GO:0043227 membrane-bounded organelle; GO:0005637 nuclear inner membrane; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0000791 euchromatin; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005635 nuclear envelope; GO:0044430 cytoskeletal part; GO:0000779 condensed chromosome, centromeric region; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0005819 spindle; GO:0031618 nuclear pericentric heterochromatin; GO:0005720 nuclear heterochromatin; GO:0043226 organelle; GO:0098687 chromosomal region; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0035985 senescence-associated heterochromatin focus; GO:0000785 chromatin; GO:0031975 envelope; GO:0000775 chromosome, centromeric region; GO:0000228 nuclear chromosome; GO:0005719 nuclear euchromatin; GO:0044428 nuclear part; ","GO:1990226 histone methyltransferase binding; GO:0019904 protein domain specific binding; GO:0005515 protein binding; GO:0042802 identical protein binding; GO:0019899 enzyme binding; GO:0005488 binding; ","K11586",null,null,"IPR017984; IPR008251; IPR023780; IPR016197; IPR000953; ","Chromo domain subgroup; Chromo shadow domain; Chromo domain; Chromo domain-like; Chromo/chromo shadow domain; \r"]
["Q13217","DnaJ homolog subfamily C member 3 OS=Homo sapiens OX=9606 GN=DNAJC3","DNAJC3",57.579,11.543,9.3,5,6,5,0.944,1.016,0.877,1.138,0.979,1.054,1.118,0.141,"extracellular\r","GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0032270 positive regulation of cellular protein metabolic process; GO:0045321 leukocyte activation; GO:0070417 cellular response to cold; GO:0010608 posttranscriptional regulation of gene expression; GO:0009891 positive regulation of biosynthetic process; GO:0098542 defense response to other organism; GO:0043555 regulation of translation in response to stress; GO:1905897 regulation of response to endoplasmic reticulum stress; GO:0044237 cellular metabolic process; GO:0009607 response to biotic stimulus; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0035966 response to topologically incorrect protein; GO:0036490 regulation of translation in response to endoplasmic reticulum stress; GO:0036494 positive regulation of translation initiation in response to endoplasmic reticulum stress; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0044419 interspecies interaction between organisms; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0051174 regulation of phosphorus metabolic process; GO:0002443 leukocyte mediated immunity; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0051704 multi-organism process; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0080135 regulation of cellular response to stress; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0030163 protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0060548 negative regulation of cell death; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0002283 neutrophil activation involved in immune response; GO:0034976 response to endoplasmic reticulum stress; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0043067 regulation of programmed cell death; GO:0044267 cellular protein metabolic process; GO:0036491 regulation of translation initiation in response to endoplasmic reticulum stress; GO:0032056 positive regulation of translation in response to stress; GO:0043558 regulation of translational initiation in response to stress; GO:0080134 regulation of response to stress; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0044248 cellular catabolic process; GO:0001933 negative regulation of protein phosphorylation; GO:0006986 response to unfolded protein; GO:0006950 response to stress; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0002263 cell activation involved in immune response; GO:1903573 negative regulation of response to endoplasmic reticulum stress; GO:0034248 regulation of cellular amide metabolic process; GO:0045055 regulated exocytosis; GO:0051247 positive regulation of protein metabolic process; GO:0032058 positive regulation of translational initiation in response to stress; GO:0031325 positive regulation of cellular metabolic process; GO:0001775 cell activation; GO:0031328 positive regulation of cellular biosynthetic process; GO:0051179 localization; GO:0006955 immune response; GO:0045936 negative regulation of phosphate metabolic process; GO:0006887 exocytosis; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0030968 endoplasmic reticulum unfolded protein response; GO:0031400 negative regulation of protein modification process; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0033673 negative regulation of kinase activity; GO:0070887 cellular response to chemical stimulus; GO:0002274 myeloid leukocyte activation; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0045727 positive regulation of translation; GO:0002446 neutrophil mediated immunity; GO:0048522 positive regulation of cellular process; GO:0051348 negative regulation of transferase activity; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0051607 defense response to virus; GO:0032940 secretion by cell; GO:0065009 regulation of molecular function; GO:0006469 negative regulation of protein kinase activity; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0043299 leukocyte degranulation; GO:0006952 defense response; GO:0043549 regulation of kinase activity; GO:0009615 response to virus; GO:0045859 regulation of protein kinase activity; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0043069 negative regulation of programmed cell death; GO:0035967 cellular response to topologically incorrect protein; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0036498 IRE1-mediated unfolded protein response; GO:0043207 response to external biotic stimulus; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0071704 organic substance metabolic process; GO:0043066 negative regulation of apoptotic process; GO:0016032 viral process; GO:0042326 negative regulation of phosphorylation; GO:0009266 response to temperature stimulus; GO:0006508 proteolysis; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0044265 cellular macromolecule catabolic process; GO:0034620 cellular response to unfolded protein; GO:0045948 positive regulation of translational initiation; GO:0001932 regulation of protein phosphorylation; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0009409 response to cold; GO:0051246 regulation of protein metabolic process; GO:1903912 negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation; GO:0006417 regulation of translation; GO:0009057 macromolecule catabolic process; GO:0010563 negative regulation of phosphorus metabolic process; GO:0034250 positive regulation of cellular amide metabolic process; GO:0006446 regulation of translational initiation; GO:0051248 negative regulation of protein metabolic process; GO:0009056 catabolic process; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0005790 smooth endoplasmic reticulum; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0030867 rough endoplasmic reticulum membrane; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0005788 endoplasmic reticulum lumen; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0005791 rough endoplasmic reticulum; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0031205 endoplasmic reticulum Sec complex; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0042582 azurophil granule; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0044432 endoplasmic reticulum part; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0030234 enzyme regulator activity; GO:0019210 kinase inhibitor activity; GO:0051087 chaperone binding; GO:0005488 binding; GO:0019901 protein kinase binding; GO:0051787 misfolded protein binding; GO:0004860 protein kinase inhibitor activity; GO:0005515 protein binding; GO:0019887 protein kinase regulator activity; GO:0019207 kinase regulator activity; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0019900 kinase binding; GO:0019899 enzyme binding; ","K09523","DNAJC3; DnaJ homolog subfamily C member 3","hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); hsa05164 Influenza A - Homo sapiens (human); ","IPR018704; IPR011990; IPR001623; IPR013026; ","Tetratricopeptide repeat-like domain; Tetratricopeptide-like helical domain; DnaJ domain; Tetratricopeptide repeat-containing domain; \r"]
["Q13242","Serine/arginine-rich splicing factor 9 OS=Homo sapiens OX=9606 GN=SRSF9","SRSF9",25.542,7.1471,13.6,3,3,3,0.992,1.243,0.976,0.91,0.947,0.953,0.875,0.184,"cyto_nucl\r","GO:0044085 cellular component biogenesis; GO:0050658 RNA transport; GO:0022613 ribonucleoprotein complex biogenesis; GO:0022618 ribonucleoprotein complex assembly; GO:0097659 nucleic acid-templated transcription; GO:0050686 negative regulation of mRNA processing; GO:0009058 biosynthetic process; GO:0051168 nuclear export; GO:0051169 nuclear transport; GO:0051253 negative regulation of RNA metabolic process; GO:1903312 negative regulation of mRNA metabolic process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006353 DNA-templated transcription, termination; GO:0071427 mRNA-containing ribonucleoprotein complex export from nucleus; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0071826 ribonucleoprotein complex subunit organization; GO:0022607 cellular component assembly; GO:0050657 nucleic acid transport; GO:0065003 macromolecular complex assembly; GO:0015931 nucleobase-containing compound transport; GO:0009719 response to endogenous stimulus; GO:0043170 macromolecule metabolic process; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0048024 regulation of mRNA splicing, via spliceosome; GO:0006396 RNA processing; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0009636 response to toxic substance; GO:1901360 organic cyclic compound metabolic process; GO:0050684 regulation of mRNA processing; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0006611 protein export from nucleus; GO:0071166 ribonucleoprotein complex localization; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:0006810 transport; GO:0010243 response to organonitrogen compound; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:1901698 response to nitrogen compound; GO:0044260 cellular macromolecule metabolic process; GO:0033119 negative regulation of RNA splicing; GO:0019222 regulation of metabolic process; GO:0006913 nucleocytoplasmic transport; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0050794 regulation of cellular process; GO:0031123 RNA 3'-end processing; GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0006376 mRNA splice site selection; GO:0006725 cellular aromatic compound metabolic process; GO:0031124 mRNA 3'-end processing; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0051028 mRNA transport; GO:0043279 response to alkaloid; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:0051236 establishment of RNA localization; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0006886 intracellular protein transport; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0034613 cellular protein localization; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0006406 mRNA export from nucleus; GO:0034622 cellular macromolecular complex assembly; GO:0010629 negative regulation of gene expression; GO:0006369 termination of RNA polymerase II transcription; GO:0006403 RNA localization; GO:0006405 RNA export from nucleus; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0051252 regulation of RNA metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0043933 macromolecular complex subunit organization; GO:0043484 regulation of RNA splicing; GO:0045184 establishment of protein localization; GO:1903311 regulation of mRNA metabolic process; GO:0070727 cellular macromolecule localization; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0071426 ribonucleoprotein complex export from nucleus; GO:0006366 transcription from RNA polymerase II promoter; GO:0010467 gene expression; GO:0051179 localization; GO:0048025 negative regulation of mRNA splicing, via spliceosome; GO:0000245 spliceosomal complex assembly; GO:0071705 nitrogen compound transport; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005730 nucleolus; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:1901265 nucleoside phosphate binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0036094 small molecule binding; ","K21123","SFRS9; splicing factor, arginine/serine-rich 9","hsa03040 Spliceosome - Homo sapiens (human); hsa05168 Herpes simplex infection - Homo sapiens (human); ","IPR000504; IPR012677; ","RNA recognition motif domain; Nucleotide-binding alpha-beta plait domain; \r"]
["Q13247","Serine/arginine-rich splicing factor 6 OS=Homo sapiens OX=9606 GN=SRSF6","SRSF6",39.586,2.8564,12.2,5,8,2,0.784,0.784,0.872,1.102,1.214,1.224,1.451,0.0016,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0050658 RNA transport; GO:0010941 regulation of cell death; GO:0022613 ribonucleoprotein complex biogenesis; GO:0000381 regulation of alternative mRNA splicing, via spliceosome; GO:0010837 regulation of keratinocyte proliferation; GO:0022618 ribonucleoprotein complex assembly; GO:0097659 nucleic acid-templated transcription; GO:0050686 negative regulation of mRNA processing; GO:0051169 nuclear transport; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:1904036 negative regulation of epithelial cell apoptotic process; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0045682 regulation of epidermis development; GO:0050678 regulation of epithelial cell proliferation; GO:0065003 macromolecular complex assembly; GO:0015931 nucleobase-containing compound transport; GO:0009719 response to endogenous stimulus; GO:0043170 macromolecule metabolic process; GO:0008104 protein localization; GO:1901652 response to peptide; GO:0006396 RNA processing; GO:0018130 heterocycle biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0045605 negative regulation of epidermal cell differentiation; GO:0032774 RNA biosynthetic process; GO:0050684 regulation of mRNA processing; GO:0031323 regulation of cellular metabolic process; GO:0006611 protein export from nucleus; GO:0006810 transport; GO:0010243 response to organonitrogen compound; GO:0030856 regulation of epithelial cell differentiation; GO:2000674 regulation of type B pancreatic cell apoptotic process; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0044260 cellular macromolecule metabolic process; GO:0033119 negative regulation of RNA splicing; GO:0006913 nucleocytoplasmic transport; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0060548 negative regulation of cell death; GO:0051094 positive regulation of developmental process; GO:0016071 mRNA metabolic process; GO:2000675 negative regulation of type B pancreatic cell apoptotic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0042127 regulation of cell proliferation; GO:0051028 mRNA transport; GO:0043067 regulation of programmed cell death; GO:1901700 response to oxygen-containing compound; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0045604 regulation of epidermal cell differentiation; GO:0048519 negative regulation of biological process; GO:0051239 regulation of multicellular organismal process; GO:0051236 establishment of RNA localization; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034613 cellular protein localization; GO:0008380 RNA splicing; GO:1904035 regulation of epithelial cell apoptotic process; GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis; GO:0006403 RNA localization; GO:0006405 RNA export from nucleus; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0071702 organic substance transport; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0043484 regulation of RNA splicing; GO:0045184 establishment of protein localization; GO:1903311 regulation of mRNA metabolic process; GO:0061041 regulation of wound healing; GO:0051179 localization; GO:0048025 negative regulation of mRNA splicing, via spliceosome; GO:1903034 regulation of response to wounding; GO:0050793 regulation of developmental process; GO:0000245 spliceosomal complex assembly; GO:0008284 positive regulation of cell proliferation; GO:0051093 negative regulation of developmental process; GO:0030857 negative regulation of epithelial cell differentiation; GO:0051241 negative regulation of multicellular organismal process; GO:0051168 nuclear export; GO:0009058 biosynthetic process; GO:0045617 negative regulation of keratinocyte differentiation; GO:0051253 negative regulation of RNA metabolic process; GO:1903312 negative regulation of mRNA metabolic process; GO:0051234 establishment of localization; GO:0006353 DNA-templated transcription, termination; GO:0071427 mRNA-containing ribonucleoprotein complex export from nucleus; GO:0051649 establishment of localization in cell; GO:0071826 ribonucleoprotein complex subunit organization; GO:0050657 nucleic acid transport; GO:0022607 cellular component assembly; GO:0045596 negative regulation of cell differentiation; GO:0033036 macromolecule localization; GO:0048024 regulation of mRNA splicing, via spliceosome; GO:0010468 regulation of gene expression; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0071166 ribonucleoprotein complex localization; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:0032868 response to insulin; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0043434 response to peptide hormone; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0045616 regulation of keratinocyte differentiation; GO:0019222 regulation of metabolic process; GO:0045683 negative regulation of epidermis development; GO:2000026 regulation of multicellular organismal development; GO:0031123 RNA 3'-end processing; GO:0006376 mRNA splice site selection; GO:0016043 cellular component organization; GO:0043069 negative regulation of programmed cell death; GO:0006725 cellular aromatic compound metabolic process; GO:0031124 mRNA 3'-end processing; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:2000027 regulation of organ morphogenesis; GO:0043066 negative regulation of apoptotic process; GO:0006886 intracellular protein transport; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0006406 mRNA export from nucleus; GO:0034622 cellular macromolecular complex assembly; GO:0010629 negative regulation of gene expression; GO:0006369 termination of RNA polymerase II transcription; GO:0006807 nitrogen compound metabolic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0051641 cellular localization; GO:0070727 cellular macromolecule localization; GO:0071426 ribonucleoprotein complex export from nucleus; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0000380 alternative mRNA splicing, via spliceosome; GO:2000794 regulation of epithelial cell proliferation involved in lung morphogenesis; GO:0006366 transcription from RNA polymerase II promoter; GO:0022603 regulation of anatomical structure morphogenesis; GO:0010467 gene expression; GO:0009725 response to hormone; GO:0042981 regulation of apoptotic process; GO:0071705 nitrogen compound transport; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:0050679 positive regulation of epithelial cell proliferation; ","GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031974 membrane-enclosed lumen; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:1901265 nucleoside phosphate binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0036002 pre-mRNA binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0036094 small molecule binding; ","K12893","SFRS4_5_6; splicing factor, arginine/serine-rich 4/5/6","hsa03040 Spliceosome - Homo sapiens (human); hsa05168 Herpes simplex infection - Homo sapiens (human); ","IPR000504; IPR012677; ","RNA recognition motif domain; Nucleotide-binding alpha-beta plait domain; \r"]
["Q13303","Voltage-gated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNAB2","KCNAB2",41,5.5914,5.7,2,3,2,0.973,0.942,0.965,1.067,0.969,1.087,1.084,0.0966,"mitochondria\r","GO:0006739 NADP metabolic process; GO:0019362 pyridine nucleotide metabolic process; GO:0045321 leukocyte activation; GO:0009117 nucleotide metabolic process; GO:0048869 cellular developmental process; GO:2000008 regulation of protein localization to cell surface; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0072524 pyridine-containing compound metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0050877 neurological system process; GO:0051234 establishment of localization; GO:0006813 potassium ion transport; GO:0008152 metabolic process; GO:0043266 regulation of potassium ion transport; GO:0006753 nucleoside phosphate metabolic process; GO:0032879 regulation of localization; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0032502 developmental process; GO:0002244 hematopoietic progenitor cell differentiation; GO:0002443 leukocyte mediated immunity; GO:0098655 cation transmembrane transport; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0002446 neutrophil mediated immunity; GO:0043269 regulation of ion transport; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0006732 coenzyme metabolic process; GO:0002520 immune system development; GO:0032501 multicellular organismal process; GO:0002444 myeloid leukocyte mediated immunity; GO:0051186 cofactor metabolic process; GO:0034762 regulation of transmembrane transport; GO:0006810 transport; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0032940 secretion by cell; GO:0044710 single-organism metabolic process; GO:0065009 regulation of molecular function; GO:0043299 leukocyte degranulation; GO:0071805 potassium ion transmembrane transport; GO:0048856 anatomical structure development; GO:0098662 inorganic cation transmembrane transport; GO:0070995 NADPH oxidation; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0034220 ion transmembrane transport; GO:0002283 neutrophil activation involved in immune response; GO:0006725 cellular aromatic compound metabolic process; GO:0046496 nicotinamide nucleotide metabolic process; GO:0002252 immune effector process; GO:0030001 metal ion transport; GO:0071804 cellular potassium ion transport; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0060341 regulation of cellular localization; GO:0030154 cell differentiation; GO:0046483 heterocycle metabolic process; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0006139 nucleobase-containing compound metabolic process; GO:0006812 cation transport; GO:0010959 regulation of metal ion transport; GO:0034641 cellular nitrogen compound metabolic process; GO:0032880 regulation of protein localization; GO:0007275 multicellular organism development; GO:0036230 granulocyte activation; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:1904062 regulation of cation transmembrane transport; GO:0003008 system process; GO:0098660 inorganic ion transmembrane transport; GO:0048731 system development; GO:0051049 regulation of transport; GO:1901379 regulation of potassium ion transmembrane transport; GO:0016192 vesicle-mediated transport; GO:0006807 nitrogen compound metabolic process; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:0043312 neutrophil degranulation; GO:0002263 cell activation involved in immune response; GO:0048534 hematopoietic or lymphoid organ development; GO:0030097 hemopoiesis; GO:0002366 leukocyte activation involved in immune response; GO:0055085 transmembrane transport; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:0034765 regulation of ion transmembrane transport; GO:0006793 phosphorus metabolic process; GO:0044767 single-organism developmental process; GO:0006811 ion transport; GO:0019637 organophosphate metabolic process; GO:0001775 cell activation; GO:0006955 immune response; GO:0051179 localization; GO:0050905 neuromuscular process; GO:0015672 monovalent inorganic cation transport; GO:1903827 regulation of cellular protein localization; GO:1901564 organonitrogen compound metabolic process; GO:0006887 exocytosis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0019898 extrinsic component of membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0009898 cytoplasmic side of plasma membrane; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:1990031 pinceau fiber; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0014069 postsynaptic density; GO:0043005 neuron projection; GO:0034702 ion channel complex; GO:0043227 membrane-bounded organelle; GO:0044306 neuron projection terminus; GO:0097458 neuron part; GO:0098552 side of membrane; GO:0031226 intrinsic component of plasma membrane; GO:0042995 cell projection; GO:0034703 cation channel complex; GO:0019897 extrinsic component of plasma membrane; GO:0012506 vesicle membrane; GO:0033267 axon part; GO:0005886 plasma membrane; GO:0008076 voltage-gated potassium channel complex; GO:0030424 axon; GO:0030667 secretory granule membrane; GO:0098794 postsynapse; GO:0099572 postsynaptic specialization; GO:0031410 cytoplasmic vesicle; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0031234 extrinsic component of cytoplasmic side of plasma membrane; GO:0098562 cytoplasmic side of membrane; GO:0043679 axon terminus; GO:0032279 asymmetric synapse; GO:0070821 tertiary granule membrane; GO:0005856 cytoskeleton; GO:0044425 membrane part; GO:0044464 cell part; GO:0098793 presynapse; GO:0044304 main axon; GO:0098805 whole membrane; GO:0030141 secretory granule; GO:1990351 transporter complex; GO:0035579 specific granule membrane; GO:0098984 neuron to neuron synapse; GO:0044456 synapse part; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0070820 tertiary granule; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:1902495 transmembrane transporter complex; GO:0044463 cell projection part; GO:0005829 cytosol; GO:0016021 integral component of membrane; GO:0044224 juxtaparanode region of axon; GO:0034705 potassium channel complex; GO:0045202 synapse; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0042581 specific granule; GO:0044444 cytoplasmic part; ","GO:0015075 ion transmembrane transporter activity; GO:0022803 passive transmembrane transporter activity; GO:0099106 ion channel regulator activity; GO:0022892 substrate-specific transporter activity; GO:0015077 monovalent inorganic cation transmembrane transporter activity; GO:0098772 molecular function regulator; GO:0015267 channel activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0016491 oxidoreductase activity; GO:0015079 potassium ion transmembrane transporter activity; GO:0016614 oxidoreductase activity, acting on CH-OH group of donors; GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; GO:0005244 voltage-gated ion channel activity; GO:0046873 metal ion transmembrane transporter activity; GO:0005249 voltage-gated potassium channel activity; GO:0015459 potassium channel regulator activity; GO:0005267 potassium channel activity; GO:0022838 substrate-specific channel activity; GO:0016247 channel regulator activity; GO:0003824 catalytic activity; GO:0022843 voltage-gated cation channel activity; GO:0005261 cation channel activity; GO:0005216 ion channel activity; GO:0022836 gated channel activity; GO:0004033 aldo-keto reductase (NADP) activity; GO:0022890 inorganic cation transmembrane transporter activity; GO:0022832 voltage-gated channel activity; GO:0008324 cation transmembrane transporter activity; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; ","K04883",null,null,"IPR023210; ","NADP-dependent oxidoreductase domain; \r"]
["Q13315","Serine-protein kinase ATM OS=Homo sapiens OX=9606 GN=ATM","ATM",350.68,5.6994,0.8,3,4,3,0.999,0.971,0.992,1.014,1.036,0.996,1.028,0.121,"plasma membrane\r",{"$cut":{"chars":22965,"head":"GO:0044700 single organism signaling; GO:0002694 regulation of leukocyte activation; GO:0050672 negative regulation of lymphocyte proliferation; GO:1902807 negative regulation of cell cycle G1/S phase transition; GO:0010941 regulation of cell death; GO:0048732 gland development; GO:0022414 reproductive process; GO:0035282 segmentation; GO:0043009 chordate embryonic development; GO:0043523 regulation of neuron apoptotic process; GO:0009891 positive regulation of biosynthetic process; GO:0044255 cellular lipid metabolic process; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0008610 lipid biosynthetic process; GO:0097695 establishment of macromolecular complex localization to telomere; GO:0072431 signal transduction involved in mitotic G1 DNA damage checkpoint; GO:1902403 signal transduction involved in mitotic DNA integrity checkpoint; GO:0033048 negative regulation of mitotic sister chromatid segregation; GO:0030888 regulation of B cell proliferation; GO:1905269 positive regulation of chromatin organization; GO:0008152 metabolic process; GO:0031577 spindle checkpoint; GO:0070664 negative regulation of leukocyte proliferation; GO:0051784 negative regulation of nuclear division; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0007140 male meiosis; GO:0090068 positive regulation of cell cycle process; GO:0009790 embryo development; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0007059 chromosome segregation; GO:0044773 mitotic DNA damage checkpoint; GO:0071214 cellular response to abiotic stimulus; GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process; GO:0051054 positive regulation of DNA metabolic process; GO:0080090 regulation of primary metabolic process; GO:0010972 negative regulation of G2/M transition of mitotic cell cycle; GO:0050864 regulation of B cell activation; GO:2000134 negative regulation of G1/S transition of mitotic cell cycle; GO:0044763 single-organism cellular process; GO:0002520 immune system development; GO:0071044 histone mRNA catabolic process; GO:0051985 negative regulation of chromosome segregation; GO:0010506 regulation of autophagy; GO:0051704 multi-organism process; GO:0019439 aromatic compound catabolic process; GO:1901575 organic substance catabolic process; GO:0080135 regulation of cellular response to stress; GO:1902532 negative regulation of intracellular signal transduction; GO:1901798 positive regulation of signal transduction by p53 class mediator; GO:0071480 cellular response to gamma radiation; GO:1902400 intracellular signal transduction involved in G1 DNA damage checkpoint; GO:0030163 protein catabolic process; GO:0006402 mRNA catabolic process; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0007143 female meiotic division; GO:0048609 multicellular organismal reproductive process; GO:0016071 mRNA metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator; GO:0048599 oocyte development; GO:0051640 organelle localization; GO:0072359 circulatory system development; GO:0000003 reproduction; GO:0016310 phosphorylation; GO:0044707 single-multicellular organism process; GO:0097190 apoptotic signaling pathway; GO:0006259 DNA metabolic process; GO:0007389 pattern specification process; GO:0009791 post-embryonic development; GO:0048519 negative regulation of biological process; GO:0001756 somitogenesis; GO:1903047 mitotic cell cycle process; GO:0030098 lymphocyte differentiation; GO:0046545 development of primary female sexual characteristics; GO:0009653 anatomical structure morphogenesis; GO:0044270 cellular nitrogen compound catabolic process; GO:0045143 homologous chromosome segregation; GO:0023057 negative regulation of signaling; GO:0046483 "}},"GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0031410 cytoplasmic vesicle; GO:0044430 cytoskeletal part; GO:0031982 vesicle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:1990391 DNA repair complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0005819 spindle; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0004677 DNA-dependent protein kinase activity; GO:0047485 protein N-terminus binding; GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:0004672 protein kinase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016301 kinase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0052742 phosphatidylinositol kinase activity; GO:0003677 DNA binding; GO:0005524 ATP binding; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0035004 phosphatidylinositol 3-kinase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003676 nucleic acid binding; GO:0032555 purine ribonucleotide binding; GO:0016303 1-phosphatidylinositol-3-kinase activity; GO:0004674 protein serine/threonine kinase activity; GO:0001883 purine nucleoside binding; GO:0032403 protein complex binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0036094 small molecule binding; ","K04728","ATM; ataxia telangiectasia mutated family protein [EC:2.7.11.1]","hsa01524 Platinum drug resistance - Homo sapiens (human); hsa04218 Cellular senescence - Homo sapiens (human); hsa04210 Apoptosis - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa04115 p53 signaling pathway - Homo sapiens (human); hsa04068 FoxO signaling pathway - Homo sapiens (human); hsa05166 HTLV-I infection - Homo sapiens (human); hsa04110 Cell cycle - Homo sapiens (human); hsa05206 MicroRNAs in cancer - Homo sapiens (human); hsa03440 Homologous recombination - Homo sapiens (human); hsa04064 NF-kappa B signaling pathway - Homo sapiens (human); hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human); ","IPR000403; IPR021668; IPR003151; IPR014009; IPR016024; IPR003152; IPR011009; ","\"Phosphatidylinositol 3-/4-kinase, catalytic domain; Telomere-length maintenance and DNA damage repair; PIK-related kinase, FAT; PIK-related kinase; Armadillo-type fold; FATC domain; Protein kinase-like domain; \"\r"]
["Q13347","Eukaryotic translation initiation factor 3 subunit I OS=Homo sapiens OX=9606 GN=EIF3I","EIF3I",36.501,39.693,24,7,11,7,0.926,0.894,0.88,1.038,1.121,1.078,1.199,0.00252,"cytoplasm\r","GO:0006518 peptide metabolic process; GO:0043043 peptide biosynthetic process; GO:0044267 cellular protein metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0009058 biosynthetic process; GO:0043603 cellular amide metabolic process; GO:0044238 primary metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0006413 translational initiation; GO:0034641 cellular nitrogen compound metabolic process; GO:0010467 gene expression; GO:0043170 macromolecule metabolic process; GO:0043604 amide biosynthetic process; GO:0019538 protein metabolic process; GO:0006412 translation; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:1901564 organonitrogen compound metabolic process; ","GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0005852 eukaryotic translation initiation factor 3 complex; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0008135 translation factor activity, RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0003743 translation initiation factor activity; GO:0005515 protein binding; ","K03246","EIF3I; translation initiation factor 3 subunit I","hsa03013 RNA transport - Homo sapiens (human); ","IPR017986; IPR015943; ","WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain; \r"]
["Q13361","Microfibrillar-associated protein 5 OS=Homo sapiens OX=9606 GN=MFAP5","MFAP5",19.611,25.758,20.2,5,18,5,1.161,1.182,1.155,0.843,0.86,0.844,0.728,2.43E-6,"extracellular\r","GO:0032502 developmental process; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0048731 system development; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0002520 immune system development; GO:0002376 immune system process; GO:0060216 definitive hemopoiesis; GO:0032501 multicellular organismal process; GO:0030097 hemopoiesis; GO:0048534 hematopoietic or lymphoid organ development; GO:0048513 animal organ development; GO:0043062 extracellular structure organization; GO:0044767 single-organism developmental process; GO:0030198 extracellular matrix organization; GO:0007275 multicellular organism development; GO:0097435 supramolecular fiber organization; GO:0009987 cellular process; GO:0048856 anatomical structure development; GO:0071840 cellular component organization or biogenesis; ","GO:0031012 extracellular matrix; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005578 proteinaceous extracellular matrix; GO:0099512 supramolecular fiber; GO:0001527 microfibril; GO:0099080 supramolecular complex; GO:0044420 extracellular matrix component; GO:0005576 extracellular region; GO:0099081 supramolecular polymer; ","GO:0005201 extracellular matrix structural constituent; GO:0005198 structural molecule activity; "]
["Q13409","Cytoplasmic dynein 1 intermediate chain 2 OS=Homo sapiens OX=9606 GN=DYNC1I2","DYNC1I2",71.456,87.797,16.1,8,10,8,1.003,0.978,1.002,0.925,1.023,0.994,0.986,0.662,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0048193 Golgi vesicle transport; GO:0060271 cilium assembly; GO:0044699 single-organism process; GO:0097711 ciliary basal body docking; GO:0044764 multi-organism cellular process; GO:1903047 mitotic cell cycle process; GO:0022406 membrane docking; GO:0044782 cilium organization; GO:0051234 establishment of localization; GO:0051649 establishment of localization in cell; GO:0070925 organelle assembly; GO:0022607 cellular component assembly; GO:0016032 viral process; GO:0044770 cell cycle phase transition; GO:0044419 interspecies interaction between organisms; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0009987 cellular process; GO:0044772 mitotic cell cycle phase transition; GO:0000278 mitotic cell cycle; GO:0016192 vesicle-mediated transport; GO:0048002 antigen processing and presentation of peptide antigen; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0002376 immune system process; GO:0002495 antigen processing and presentation of peptide antigen via MHC class II; GO:0007017 microtubule-based process; GO:0030031 cell projection assembly; GO:0051704 multi-organism process; GO:0051641 cellular localization; GO:0006810 transport; GO:1902589 single-organism organelle organization; GO:0007018 microtubule-based movement; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0019882 antigen processing and presentation; GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; GO:0030030 cell projection organization; GO:0006996 organelle organization; GO:0006928 movement of cell or subcellular component; GO:0022402 cell cycle process; GO:0044839 cell cycle G2/M phase transition; GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II; GO:0051179 localization; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0000086 G2/M transition of mitotic cell cycle; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; ","GO:0005874 microtubule; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0005623 cell; GO:0099080 supramolecular complex; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0005815 microtubule organizing center; GO:1902494 catalytic complex; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0030286 dynein complex; GO:0005875 microtubule associated complex; GO:0005829 cytosol; GO:0005868 cytoplasmic dynein complex; GO:0099081 supramolecular polymer; GO:0043226 organelle; GO:0005813 centrosome; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0003774 motor activity; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0003777 microtubule motor activity; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017111 nucleoside-triphosphatase activity; ","K10415","DYNC1I; dynein intermediate chain, cytosolic","hsa05132 Salmonella infection - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); hsa04962 Vasopressin-regulated water reabsorption - Homo sapiens (human); ","IPR017986; IPR015943; ","WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain; \r"]
["Q13423","NAD(P) transhydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=NNT","NNT",113.89,183.5,16.6,15,26,15,1.074,1.082,1.087,0.927,0.931,0.908,0.853,4.37e-05,"plasma membrane\r","GO:0006739 NADP metabolic process; GO:0034220 ion transmembrane transport; GO:0019362 pyridine nucleotide metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0046496 nicotinamide nucleotide metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0072524 pyridine-containing compound metabolic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:1902578 single-organism localization; GO:0006091 generation of precursor metabolites and energy; GO:0072593 reactive oxygen species metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0006812 cation transport; GO:0006753 nucleoside phosphate metabolic process; GO:1902600 hydrogen ion transmembrane transport; GO:0034641 cellular nitrogen compound metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0044765 single-organism transport; GO:0072350 tricarboxylic acid metabolic process; GO:0098655 cation transmembrane transport; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0098660 inorganic ion transmembrane transport; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0006099 tricarboxylic acid cycle; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0006732 coenzyme metabolic process; GO:0044238 primary metabolic process; GO:0045333 cellular respiration; GO:0015992 proton transport; GO:0006818 hydrogen transport; GO:0051186 cofactor metabolic process; GO:0006101 citrate metabolic process; GO:0006810 transport; GO:0055085 transmembrane transport; GO:0006740 NADPH regeneration; GO:0006793 phosphorus metabolic process; GO:0009060 aerobic respiration; GO:0044710 single-organism metabolic process; GO:0006811 ion transport; GO:0015980 energy derivation by oxidation of organic compounds; GO:0019752 carboxylic acid metabolic process; GO:0019637 organophosphate metabolic process; GO:0006082 organic acid metabolic process; GO:0051179 localization; GO:0015672 monovalent inorganic cation transport; GO:0098662 inorganic cation transmembrane transport; GO:0043436 oxoacid metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044429 mitochondrial part; GO:0031090 organelle membrane; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0005746 mitochondrial respiratory chain; GO:0005740 mitochondrial envelope; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0031975 envelope; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0031966 mitochondrial membrane; GO:0070469 respiratory chain; GO:0044444 cytoplasmic part; ","GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:1901265 nucleoside phosphate binding; GO:0015075 ion transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0003957 NAD(P)+ transhydrogenase (B-specific) activity; GO:0015077 monovalent inorganic cation transmembrane transporter activity; GO:0000166 nucleotide binding; GO:0048037 cofactor binding; GO:0015078 hydrogen ion transmembrane transporter activity; GO:0008746 NAD(P)+ transhydrogenase activity; GO:0008750 NAD(P)+ transhydrogenase (AB-specific) activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0016491 oxidoreductase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0016652 oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor; GO:0051287 NAD binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0050661 NADP binding; GO:0022890 inorganic cation transmembrane transporter activity; GO:0008324 cation transmembrane transporter activity; GO:0036094 small molecule binding; GO:0050662 coenzyme binding; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; ","K00323","NNT; NAD(P) transhydrogenase [EC:1.6.1.2]","hsa00760 Nicotinate and nicotinamide metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR007698; IPR029035; IPR016040; IPR007886; IPR034300; IPR024605; ","\"Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain; DHS-like NAD/FAD-binding domain; NAD(P)-binding domain; Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal; NADP transhydrogenase beta-like domain; NAD(P) transhydrogenase, alpha subunit, C-terminal; \"\r"]
["Q13439","Golgin subfamily A member 4 OS=Homo sapiens OX=9606 GN=GOLGA4","GOLGA4",261.14,13.635,2.2,5,7,5,0.921,0.819,0.986,1.033,1.068,1.163,1.197,0.0483,"nucleus\r","GO:0010256 endomembrane system organization; GO:0065008 regulation of biological quality; GO:0045666 positive regulation of neuron differentiation; GO:0072594 establishment of protein localization to organelle; GO:0048869 cellular developmental process; GO:0090002 establishment of protein localization to plasma membrane; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0015031 protein transport; GO:0045927 positive regulation of growth; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0001558 regulation of cell growth; GO:0051130 positive regulation of cellular component organization; GO:0051649 establishment of localization in cell; GO:0051240 positive regulation of multicellular organismal process; GO:0006893 Golgi to plasma membrane transport; GO:0032535 regulation of cellular component size; GO:0033365 protein localization to organelle; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0010720 positive regulation of cell development; GO:0044765 single-organism transport; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0048639 positive regulation of developmental growth; GO:0072657 protein localization to membrane; GO:0030307 positive regulation of cell growth; GO:0006891 intra-Golgi vesicle-mediated transport; GO:0048699 generation of neurons; GO:0031346 positive regulation of cell projection organization; GO:0000301 retrograde transport, vesicle recycling within Golgi; GO:0044763 single-organism cellular process; GO:0045773 positive regulation of axon extension; GO:0051962 positive regulation of nervous system development; GO:0048522 positive regulation of cellular process; GO:0007009 plasma membrane organization; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0045664 regulation of neuron differentiation; GO:0048856 anatomical structure development; GO:0051094 positive regulation of developmental process; GO:0010975 regulation of neuron projection development; GO:2000026 regulation of multicellular organismal development; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0040008 regulation of growth; GO:0048193 Golgi vesicle transport; GO:0010770 positive regulation of cell morphogenesis involved in differentiation; GO:0031344 regulation of cell projection organization; GO:0048638 regulation of developmental growth; GO:1990778 protein localization to cell periphery; GO:0045597 positive regulation of cell differentiation; GO:0051239 regulation of multicellular organismal process; GO:0030154 cell differentiation; GO:0008361 regulation of cell size; GO:1902578 single-organism localization; GO:0050772 positive regulation of axonogenesis; GO:0006886 intracellular protein transport; GO:0043001 Golgi to plasma membrane protein transport; GO:1902580 single-organism cellular localization; GO:0007275 multicellular organism development; GO:0034613 cellular protein localization; GO:0090150 establishment of protein localization to membrane; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0034067 protein localization to Golgi apparatus; GO:0098876 vesicle-mediated transport to the plasma membrane; GO:0048731 system development; GO:0072600 establishment of protein localization to Golgi; GO:0016192 vesicle-mediated transport; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0044802 single-organism membrane organization; GO:0071702 organic substance transport; GO:0048518 positive regulation of biological process; GO:0050770 regulation of axonogenesis; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0072659 protein localization to plasma membrane; GO:0010976 positive regulation of neuron projection development; GO:0030516 regulation of axon extension; GO:0044767 single-organism developmental process; GO:0061024 membrane organization; GO:0022603 regulation of anatomical structure morphogenesis; GO:0061387 regulation of extent of cell growth; GO:0090066 regulation of anatomical structure size; GO:0050769 positive regulation of neurogenesis; GO:0051128 regulation of cellular component organization; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:0000042 protein targeting to Golgi; GO:0006892 post-Golgi vesicle-mediated transport; GO:0051179 localization; GO:0022604 regulation of cell morphogenesis; GO:0050793 regulation of developmental process; GO:0050767 regulation of neurogenesis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0098588 bounding membrane of organelle; GO:0031090 organelle membrane; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0005622 intracellular; GO:0044464 cell part; GO:0098791 Golgi subcompartment; GO:0005802 trans-Golgi network; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0005794 Golgi apparatus; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0031984 organelle subcompartment; ","GO:0005515 protein binding; GO:0051020 GTPase binding; GO:0019899 enzyme binding; GO:0005488 binding; ","K20283",null,null,"IPR000237; ","GRIP domain; \r"]
["Q13443","Disintegrin and metalloproteinase domain-containing protein 9 OS=Homo sapiens OX=9606 GN=ADAM9","ADAM9",90.555,10.089,3.7,2,2,2,0.995,1.028,0.856,0.946,1.187,0.992,1.085,0.419,"plasma membrane\r","GO:0044700 single organism signaling; GO:0030335 positive regulation of cell migration; GO:0045321 leukocyte activation; GO:0032270 positive regulation of cellular protein metabolic process; GO:0007166 cell surface receptor signaling pathway; GO:0060142 regulation of syncytium formation by plasma membrane fusion; GO:0009607 response to biotic stimulus; GO:0009913 epidermal cell differentiation; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0022610 biological adhesion; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0048545 response to steroid hormone; GO:0007160 cell-matrix adhesion; GO:0009719 response to endogenous stimulus; GO:0008544 epidermis development; GO:0007155 cell adhesion; GO:0070848 response to growth factor; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0051347 positive regulation of transferase activity; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0014070 response to organic cyclic compound; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0043588 skin development; GO:0051174 regulation of phosphorus metabolic process; GO:0010632 regulation of epithelial cell migration; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0000302 response to reactive oxygen species; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0051272 positive regulation of cellular component movement; GO:0048870 cell motility; GO:0051549 positive regulation of keratinocyte migration; GO:0071559 response to transforming growth factor beta; GO:0034239 regulation of macrophage fusion; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0071396 cellular response to lipid; GO:0051704 multi-organism process; GO:0048513 animal organ development; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0098602 single organism cell adhesion; GO:0050714 positive regulation of protein secretion; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051223 regulation of protein transport; GO:0033631 cell-cell adhesion mediated by integrin; GO:0051094 positive regulation of developmental process; GO:0042117 monocyte activation; GO:0051047 positive regulation of secretion; GO:0030855 epithelial cell differentiation; GO:0006509 membrane protein ectodomain proteolysis; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0031399 regulation of protein modification process; GO:1901700 response to oxygen-containing compound; GO:2000147 positive regulation of cell motility; GO:0051239 regulation of multicellular organismal process; GO:0032147 activation of protein kinase activity; GO:2000145 regulation of cell motility; GO:0051043 regulation of membrane protein ectodomain proteolysis; GO:0009896 positive regulation of catabolic process; GO:0051338 regulation of transferase activity; GO:0032880 regulation of protein localization; GO:0007275 multicellular organism development; GO:0042176 regulation of protein catabolic process; GO:0009966 regulation of signal transduction; GO:0009617 response to bacterium; GO:1902531 regulation of intracellular signal transduction; GO:0045785 positive regulation of cell adhesion; GO:0006950 response to stress; GO:0051270 regulation of cellular component movement; GO:0032496 response to lipopolysaccharide; GO:0048731 system development; GO:0007179 transforming growth factor beta receptor signaling pathway; GO:0002376 immune system process; GO:0030334 regulation of cell migration; GO:0030162 regulation of proteolysis; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0030155 regulation of cell adhesion; GO:0051247 positive regulation of protein metabolic process; GO:1904951 positive regulation of establishment of protein localization; GO:0042542 response to hydrogen peroxide; GO:0031325 positive regulation of cellular metabolic process; GO:0071219 cellular response to molecule of bacterial origin; GO:0001775 cell activation; GO:0006928 movement of cell or subcellular component; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0051674 localization of cell; GO:0040017 positive regulation of locomotion; GO:0033627 cell adhesion mediated by integrin; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:0031331 positive regulation of cellular catabolic process; GO:0071560 cellular response to transforming growth factor beta stimulus; GO:1902533 positive regulation of intracellular signal transduction; GO:0051046 regulation of secretion; GO:0044699 single-organism process; GO:0071363 cellular response to growth factor stimulus; GO:0033619 membrane protein proteolysis; GO:0000186 activation of MAPKK activity; GO:0051130 positive regulation of cellular component organization; GO:0016337 single organismal cell-cell adhesion; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0006979 response to oxidative stress; GO:0010035 response to inorganic substance; GO:0034612 response to tumor necrosis factor; GO:0033674 positive regulation of kinase activity; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0070887 cellular response to chemical stimulus; GO:0051088 PMA-inducible membrane protein ectodomain proteolysis; GO:0034241 positive regulation of macrophage fusion; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0045937 positive regulation of phosphate metabolic process; GO:0009888 tissue development; GO:0030216 keratinocyte differentiation; GO:0034097 response to cytokine; GO:0002237 response to molecule of bacterial origin; GO:0098609 cell-cell adhesion; GO:0048522 positive regulation of cellular process; GO:1903530 regulation of secretion by cell; GO:0007229 integrin-mediated signaling pathway; GO:0023052 signaling; GO:0034616 response to laminar fluid shear stress; GO:0051384 response to glucocorticoid; GO:0010038 response to metal ion; GO:0051050 positive regulation of transport; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:1903532 positive regulation of secretion by cell; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0040011 locomotion; GO:0019220 regulation of phosphate metabolic process; GO:0048856 anatomical structure development; GO:0033630 positive regulation of cell adhesion mediated by integrin; GO:0051222 positive regulation of protein transport; GO:0043549 regulation of kinase activity; GO:0045859 regulation of protein kinase activity; GO:0016477 cell migration; GO:0071222 cellular response to lipopolysaccharide; GO:0060255 regulation of macromolecule metabolic process; GO:0043405 regulation of MAP kinase activity; GO:0051547 regulation of keratinocyte migration; GO:0071310 cellular response to organic substance; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0060143 positive regulation of syncytium formation by plasma membrane fusion; GO:0051707 response to other organism; GO:0070201 regulation of establishment of protein localization; GO:0071704 organic substance metabolic process; GO:0033993 response to lipid; GO:0030154 cell differentiation; GO:0045862 positive regulation of proteolysis; GO:0071216 cellular response to biotic stimulus; GO:0051044 positive regulation of membrane protein ectodomain proteolysis; GO:0043408 regulation of MAPK cascade; GO:0023056 positive regulation of signaling; GO:0031960 response to corticosteroid; GO:0051592 response to calcium ion; GO:0010042 response to manganese ion; GO:0006508 proteolysis; GO:0010647 positive regulation of cell communication; GO:0050708 regulation of protein secretion; GO:0034405 response to fluid shear stress; GO:0009987 cellular process; GO:0051049 regulation of transport; GO:0033628 regulation of cell adhesion mediated by integrin; GO:0001932 regulation of protein phosphorylation; GO:0031401 positive regulation of protein modification process; GO:0010634 positive regulation of epithelial cell migration; GO:0001934 positive regulation of protein phosphorylation; GO:0045860 positive regulation of protein kinase activity; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:1901701 cellular response to oxygen-containing compound; GO:0031589 cell-substrate adhesion; GO:0071495 cellular response to endogenous stimulus; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0009967 positive regulation of signal transduction; GO:0045732 positive regulation of protein catabolic process; GO:0051128 regulation of cellular component organization; GO:0009725 response to hormone; GO:0040012 regulation of locomotion; GO:0043410 positive regulation of MAPK cascade; GO:0065007 biological regulation; ","GO:0016323 basolateral plasma membrane; GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0009897 external side of plasma membrane; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0005623 cell; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0098590 plasma membrane region; GO:0044464 cell part; GO:0044425 membrane part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0031233 intrinsic component of external side of plasma membrane; GO:0005924 cell-substrate adherens junction; GO:0098552 side of membrane; GO:0031226 intrinsic component of plasma membrane; GO:0070161 anchoring junction; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0009986 cell surface; GO:0043230 extracellular organelle; ","GO:0004222 metalloendopeptidase activity; GO:0008233 peptidase activity; GO:0005102 receptor binding; GO:0019901 protein kinase binding; GO:0043167 ion binding; GO:0044877 macromolecular complex binding; GO:0008237 metallopeptidase activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0005178 integrin binding; GO:0019900 kinase binding; GO:0017124 SH3 domain binding; GO:0050840 extracellular matrix binding; GO:0004175 endopeptidase activity; GO:0050839 cell adhesion molecule binding; GO:0043236 laminin binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0005080 protein kinase C binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0019904 protein domain specific binding; GO:0005518 collagen binding; GO:0019899 enzyme binding; GO:0032403 protein complex binding; ","K06834",null,null,"IPR034027; IPR024079; IPR001762; IPR006586; IPR002870; IPR000742; IPR001590; ","\"Reprolysin domain, adamalysin-type; Metallopeptidase, catalytic domain; Disintegrin domain; ADAM, cysteine-rich; Peptidase M12B, propeptide; EGF-like domain; Peptidase M12B, ADAM/reprolysin; \"\r"]
["Q13464","Rho-associated protein kinase 1 OS=Homo sapiens OX=9606 GN=ROCK1","ROCK1",158.17,12.035,4.7,7,7,6,1.037,1.01,1.011,0.935,1.036,0.98,0.965,0.304,"nucleus\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0010941 regulation of cell death; GO:0045321 leukocyte activation; GO:0007166 cell surface receptor signaling pathway; GO:0043523 regulation of neuron apoptotic process; GO:0032989 cellular component morphogenesis; GO:0090002 establishment of protein localization to plasma membrane; GO:0032091 negative regulation of protein binding; GO:0044237 cellular metabolic process; GO:0022610 biological adhesion; GO:0030036 actin cytoskeleton organization; GO:0008152 metabolic process; GO:0051894 positive regulation of focal adhesion assembly; GO:0045682 regulation of epidermis development; GO:0032879 regulation of localization; GO:0007155 cell adhesion; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0051493 regulation of cytoskeleton organization; GO:0008104 protein localization; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0035305 negative regulation of dephosphorylation; GO:0001954 positive regulation of cell-matrix adhesion; GO:0051716 cellular response to stimulus; GO:0002064 epithelial cell development; GO:0051174 regulation of phosphorus metabolic process; GO:0002443 leukocyte mediated immunity; GO:0035507 regulation of myosin-light-chain-phosphatase activity; GO:2000810 regulation of bicellular tight junction assembly; GO:0072657 protein localization to membrane; GO:0080090 regulation of primary metabolic process; GO:0050901 leukocyte tethering or rolling; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0048870 cell motility; GO:0007264 small GTPase mediated signal transduction; GO:0007009 plasma membrane organization; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:1901888 regulation of cell junction assembly; GO:0032501 multicellular organismal process; GO:1901343 negative regulation of vasculature development; GO:0010811 positive regulation of cell-substrate adhesion; GO:0000902 cell morphogenesis; GO:0006810 transport; GO:0030856 regulation of epithelial cell differentiation; GO:0050900 leukocyte migration; GO:0006939 smooth muscle contraction; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0035304 regulation of protein dephosphorylation; GO:0044260 cellular macromolecule metabolic process; GO:0098602 single organism cell adhesion; GO:2000114 regulation of establishment of cell polarity; GO:0097194 execution phase of apoptosis; GO:0045765 regulation of angiogenesis; GO:0006464 cellular protein modification process; GO:0048010 vascular endothelial growth factor receptor signaling pathway; GO:0060548 negative regulation of cell death; GO:0030855 epithelial cell differentiation; GO:1902903 regulation of supramolecular fiber organization; GO:0050794 regulation of cellular process; GO:0016310 phosphorylation; GO:0001952 regulation of cell-matrix adhesion; GO:0032515 negative regulation of phosphoprotein phosphatase activity; GO:0002283 neutrophil activation involved in immune response; GO:0032956 regulation of actin cytoskeleton organization; GO:0031399 regulation of protein modification process; GO:1901889 negative regulation of cell junction assembly; GO:0044267 cellular protein metabolic process; GO:0043067 regulation of programmed cell death; GO:0045604 regulation of epidermal cell differentiation; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0051239 regulation of multicellular organismal process; GO:1990778 protein localization to cell periphery; GO:0009653 anatomical structure morphogenesis; GO:0002275 myeloid cell activation involved in immune response; GO:0043524 negative regulation of neuron apoptotic process; GO:1902578 single-organism localization; GO:2000145 regulation of cell motility; GO:0035308 negative regulation of protein dephosphorylation; GO:1902580 single-organism cellular localization; GO:1903347 negative regulation of bicellular tight junction assembly; GO:0007010 cytoskeleton organization; GO:0034613 cellular protein localization; GO:0090150 establishment of protein localization to membrane; GO:0051451 myoblast migration; GO:1901550 regulation of endothelial cell development; GO:1901215 negative regulation of neuron death; GO:0045785 positive regulation of cell adhesion; GO:0051270 regulation of cellular component movement; GO:0032231 regulation of actin filament bundle assembly; GO:0060284 regulation of cell development; GO:0016192 vesicle-mediated transport; GO:0061756 leukocyte adhesion to vascular endothelial cell; GO:0002376 immune system process; GO:0032970 regulation of actin filament-based process; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0002263 cell activation involved in immune response; GO:0030155 regulation of cell adhesion; GO:0030031 cell projection assembly; GO:0051492 regulation of stress fiber assembly; GO:0045184 establishment of protein localization; GO:0045055 regulated exocytosis; GO:0072659 protein localization to plasma membrane; GO:0003382 epithelial cell morphogenesis; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0045123 cellular extravasation; GO:0030029 actin filament-based process; GO:0061024 membrane organization; GO:0001775 cell activation; GO:0006928 movement of cell or subcellular component; GO:0007249 I-kappaB kinase/NF-kappaB signaling; GO:0012501 programmed cell death; GO:0006955 immune response; GO:0043412 macromolecule modification; GO:0051179 localization; GO:0010810 regulation of cell-substrate adhesion; GO:0050793 regulation of developmental process; GO:0045936 negative regulation of phosphate metabolic process; GO:0006887 exocytosis; GO:0030048 actin filament-based movement; GO:0051093 negative regulation of developmental process; GO:0070252 actin-mediated cell contraction; GO:0003012 muscle system process; GO:0010256 endomembrane system organization; GO:1903391 regulation of adherens junction organization; GO:0051674 localization of cell; GO:0048869 cellular developmental process; GO:0051129 negative regulation of cellular component organization; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0090109 regulation of cell-substrate junction assembly; GO:0010923 negative regulation of phosphatase activity; GO:0031400 negative regulation of protein modification process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0016337 single organismal cell-cell adhesion; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0006915 apoptotic process; GO:0035303 regulation of dephosphorylation; GO:0007266 Rho protein signal transduction; GO:0033036 macromolecule localization; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:2000181 negative regulation of blood vessel morphogenesis; GO:0060429 epithelium development; GO:0009888 tissue development; GO:0032878 regulation of establishment or maintenance of cell polarity; GO:0030866 cortical actin cytoskeleton organization; GO:0002446 neutrophil mediated immunity; GO:0098609 cell-cell adhesion; GO:0051098 regulation of binding; GO:0048522 positive regulation of cellular process; GO:1901890 positive regulation of cell junction assembly; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0035509 negative regulation of myosin-light-chain-phosphatase activity; GO:0002444 myeloid leukocyte mediated immunity; GO:1902589 single-organism organelle organization; GO:1903393 positive regulation of adherens junction organization; GO:0016525 negative regulation of angiogenesis; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0051100 negative regulation of binding; GO:0030030 cell projection organization; GO:0032940 secretion by cell; GO:0045616 regulation of keratinocyte differentiation; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0043299 leukocyte degranulation; GO:0040011 locomotion; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0007265 Ras protein signal transduction; GO:0003383 apical constriction; GO:2000026 regulation of multicellular organismal development; GO:0016043 cellular component organization; GO:0016477 cell migration; GO:0007159 leukocyte cell-cell adhesion; GO:0043666 regulation of phosphoprotein phosphatase activity; GO:0043069 negative regulation of programmed cell death; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0051893 regulation of focal adhesion assembly; GO:0044087 regulation of cellular component biogenesis; GO:0031324 negative regulation of cellular metabolic process; GO:0030865 cortical cytoskeleton organization; GO:0050896 response to stimulus; GO:0022406 membrane docking; GO:0048468 cell development; GO:0051346 negative regulation of hydrolase activity; GO:0000904 cell morphogenesis involved in differentiation; GO:0071704 organic substance metabolic process; GO:0032060 bleb assembly; GO:0043393 regulation of protein binding; GO:0030154 cell differentiation; GO:0006936 muscle contraction; GO:0048013 ephrin receptor signaling pathway; GO:0006468 protein phosphorylation; GO:0043066 negative regulation of apoptotic process; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:1901214 regulation of neuron death; GO:0045595 regulation of cell differentiation; GO:0003008 system process; GO:0010921 regulation of phosphatase activity; GO:0035556 intracellular signal transduction; GO:1901342 regulation of vasculature development; GO:0033043 regulation of organelle organization; GO:0044802 single-organism membrane organization; GO:0043312 neutrophil degranulation; GO:0045601 regulation of endothelial cell differentiation; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0070727 cellular macromolecule localization; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0010563 negative regulation of phosphorus metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0022614 membrane to membrane docking; GO:0014812 muscle cell migration; GO:0051128 regulation of cellular component organization; GO:0040012 regulation of locomotion; GO:1903140 regulation of establishment of endothelial barrier; GO:0044089 positive regulation of cellular component biogenesis; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0034774 secretory granule lumen; GO:0044450 microtubule organizing center part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0032059 bleb; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0031974 membrane-enclosed lumen; GO:0005815 microtubule organizing center; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0030027 lamellipodium; GO:0044431 Golgi apparatus part; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0031252 cell leading edge; GO:0042995 cell projection; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0005813 centrosome; GO:0001726 ruffle; GO:0005814 centriole; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0005515 protein binding; GO:0004672 protein kinase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016301 kinase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0017016 Ras GTPase binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0051020 GTPase binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0031267 small GTPase binding; GO:0017048 Rho GTPase binding; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017049 GTP-Rho binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0046872 metal ion binding; GO:0004674 protein serine/threonine kinase activity; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019899 enzyme binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0036094 small molecule binding; ","K04514","ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]","hsa04921 Oxytocin signaling pathway - Homo sapiens (human); hsa05132 Salmonella infection - Homo sapiens (human); hsa04530 Tight junction - Homo sapiens (human); hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human); hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human); hsa04270 Vascular smooth muscle contraction - Homo sapiens (human); hsa04350 TGF-beta signaling pathway - Homo sapiens (human); hsa04024 cAMP signaling pathway - Homo sapiens (human); hsa04670 Leukocyte transendothelial migration - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa05206 MicroRNAs in cancer - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); hsa05131 Shigellosis - Homo sapiens (human); hsa04062 Chemokine signaling pathway - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa04071 Sphingolipid signaling pathway - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa04611 Platelet activation - Homo sapiens (human); hsa04360 Axon guidance - Homo sapiens (human); ","IPR002219; IPR015008; IPR000719; IPR011993; IPR001849; IPR011009; IPR000961; ","\"Protein kinase C-like, phorbol ester/diacylglycerol-binding domain; Rho binding domain; Protein kinase domain; PH domain-like; Pleckstrin homology domain; Protein kinase-like domain; AGC-kinase, C-terminal; \"\r"]
["Q13505","Metaxin-1 OS=Homo sapiens OX=9606 GN=MTX1","MTX1",51.462,17.831,7.1,2,2,2,0.983,0.872,1.029,1.051,1.032,1.034,1.081,0.248,"nucleus\r","GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0072594 establishment of protein localization to organelle; GO:0006839 mitochondrial transport; GO:0071702 organic substance transport; GO:0070585 protein localization to mitochondrion; GO:0015031 protein transport; GO:0051641 cellular localization; GO:0051234 establishment of localization; GO:0006810 transport; GO:0045184 establishment of protein localization; GO:0006605 protein targeting; GO:0070727 cellular macromolecule localization; GO:0051649 establishment of localization in cell; GO:0006996 organelle organization; GO:0007005 mitochondrion organization; GO:0006886 intracellular protein transport; GO:0006626 protein targeting to mitochondrion; GO:0033365 protein localization to organelle; GO:0034613 cellular protein localization; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0051179 localization; GO:0072655 establishment of protein localization to mitochondrion; GO:0009987 cellular process; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0019867 outer membrane; GO:0044429 mitochondrial part; GO:0098588 bounding membrane of organelle; GO:0031090 organelle membrane; GO:0005741 mitochondrial outer membrane; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005740 mitochondrial envelope; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0031975 envelope; GO:0098805 whole membrane; GO:0031968 organelle outer membrane; GO:0043227 membrane-bounded organelle; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ",null,"K17776",null,null,"IPR010987; IPR019564; IPR033468; ","\"Glutathione S-transferase, C-terminal-like; Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain; Metaxin, glutathione S-transferase domain; \"\r"]
["Q13510","Acid ceramidase OS=Homo sapiens OX=9606 GN=ASAH1","ASAH1",44.659,90.202,31.1,13,22,13,0.992,1.023,1.032,0.98,0.928,0.977,0.947,0.0623,"extracellular\r","GO:1903509 liposaccharide metabolic process; GO:0045321 leukocyte activation; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0006643 membrane lipid metabolic process; GO:0006672 ceramide metabolic process; GO:0006687 glycosphingolipid metabolic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0006665 sphingolipid metabolic process; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0006629 lipid metabolic process; GO:0002443 leukocyte mediated immunity; GO:0002446 neutrophil mediated immunity; GO:0016192 vesicle-mediated transport; GO:0006664 glycolipid metabolic process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:0002376 immune system process; GO:0043603 cellular amide metabolic process; GO:0043312 neutrophil degranulation; GO:0044238 primary metabolic process; GO:0002263 cell activation involved in immune response; GO:0002444 myeloid leukocyte mediated immunity; GO:0006810 transport; GO:0002366 leukocyte activation involved in immune response; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:0032940 secretion by cell; GO:0044710 single-organism metabolic process; GO:0001775 cell activation; GO:0043299 leukocyte degranulation; GO:0051179 localization; GO:0006955 immune response; GO:0006887 exocytosis; GO:1901564 organonitrogen compound metabolic process; ","GO:1904724 tertiary granule lumen; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0101002 ficolin-1-rich granule; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0070820 tertiary granule; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0043202 lysosomal lumen; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016787 hydrolase activity; GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; GO:0017040 ceramidase activity; GO:0003824 catalytic activity; GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; ","K12348","ASAH1; acid ceramidase [EC:3.5.1.23]","hsa04142 Lysosome - Homo sapiens (human); hsa04071 Sphingolipid signaling pathway - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00600 Sphingolipid metabolism - Homo sapiens (human); ","IPR029130; IPR029132; ","\"Acid ceramidase, N-terminal; Choloylglycine hydrolase/NAAA C-terminal; \"\r"]
["Q13526","Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 OS=Homo sapiens OX=9606 GN=PIN1","PIN1",18.243,2.8303,9.2,1,1,1,1.053,0.999,0.968,0.957,0.987,1.044,0.989,0.777,"cytoplasm\r","GO:0065008 regulation of biological quality; GO:0010941 regulation of cell death; GO:0032270 positive regulation of cellular protein metabolic process; GO:0051443 positive regulation of ubiquitin-protein transferase activity; GO:0009891 positive regulation of biosynthetic process; GO:0043523 regulation of neuron apoptotic process; GO:0014742 positive regulation of muscle hypertrophy; GO:0032091 negative regulation of protein binding; GO:1903845 negative regulation of cellular response to transforming growth factor beta stimulus; GO:0044237 cellular metabolic process; GO:0010564 regulation of cell cycle process; GO:0045927 positive regulation of growth; GO:0001558 regulation of cell growth; GO:0061050 regulation of cell growth involved in cardiac muscle cell development; GO:0008152 metabolic process; GO:0014743 regulation of muscle hypertrophy; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0090263 positive regulation of canonical Wnt signaling pathway; GO:0044093 positive regulation of molecular function; GO:0044057 regulation of system process; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0051347 positive regulation of transferase activity; GO:2000727 positive regulation of cardiac muscle cell differentiation; GO:0051147 regulation of muscle cell differentiation; GO:0007399 nervous system development; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0055025 positive regulation of cardiac muscle tissue development; GO:0030307 positive regulation of cell growth; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0007088 regulation of mitotic nuclear division; GO:0045893 positive regulation of transcription, DNA-templated; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0060828 regulation of canonical Wnt signaling pathway; GO:0090287 regulation of cellular response to growth factor stimulus; GO:2000146 negative regulation of cell motility; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0043525 positive regulation of neuron apoptotic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0051336 regulation of hydrolase activity; GO:1902532 negative regulation of intracellular signal transduction; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0035304 regulation of protein dephosphorylation; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0051149 positive regulation of muscle cell differentiation; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0051094 positive regulation of developmental process; GO:1901863 positive regulation of muscle tissue development; GO:0060548 negative regulation of cell death; GO:0043068 positive regulation of programmed cell death; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0007346 regulation of mitotic cell cycle; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0043067 regulation of programmed cell death; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0051239 regulation of multicellular organismal process; GO:0045597 positive regulation of cell differentiation; GO:0060341 regulation of cellular localization; GO:0023057 negative regulation of signaling; GO:0070372 regulation of ERK1 and ERK2 cascade; GO:0010648 negative regulation of cell communication; GO:0043524 negative regulation of neuron apoptotic process; GO:0051345 positive regulation of hydrolase activity; GO:2000145 regulation of cell motility; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0045844 positive regulation of striated muscle tissue development; GO:0070373 negative regulation of ERK1 and ERK2 cascade; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0001933 negative regulation of protein phosphorylation; GO:0032880 regulation of protein localization; GO:0007275 multicellular organism development; GO:0042176 regulation of protein catabolic process; GO:0009966 regulation of signal transduction; GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development; GO:1901215 negative regulation of neuron death; GO:0051254 positive regulation of RNA metabolic process; GO:1902531 regulation of intracellular signal transduction; GO:0051270 regulation of cellular component movement; GO:0043547 positive regulation of GTPase activity; GO:0048731 system development; GO:0060284 regulation of cell development; GO:0000413 protein peptidyl-prolyl isomerization; GO:0044238 primary metabolic process; GO:0050808 synapse organization; GO:0009892 negative regulation of metabolic process; GO:0010611 regulation of cardiac muscle hypertrophy; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0030182 neuron differentiation; GO:0043502 regulation of muscle adaptation; GO:0051247 positive regulation of protein metabolic process; GO:0031398 positive regulation of protein ubiquitination; GO:0051438 regulation of ubiquitin-protein transferase activity; GO:0030111 regulation of Wnt signaling pathway; GO:0010613 positive regulation of cardiac muscle hypertrophy; GO:0031325 positive regulation of cellular metabolic process; GO:0043409 negative regulation of MAPK cascade; GO:0030177 positive regulation of Wnt signaling pathway; GO:0031647 regulation of protein stability; GO:0043412 macromolecule modification; GO:0031328 positive regulation of cellular biosynthetic process; GO:0048584 positive regulation of response to stimulus; GO:0050793 regulation of developmental process; GO:0050821 protein stabilization; GO:1903827 regulation of cellular protein localization; GO:0045936 negative regulation of phosphate metabolic process; GO:0046620 regulation of organ growth; GO:0055021 regulation of cardiac muscle tissue growth; GO:0009968 negative regulation of signal transduction; GO:0060420 regulation of heart growth; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:0048634 regulation of muscle organ development; GO:0051241 negative regulation of multicellular organismal process; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:2000725 regulation of cardiac muscle cell differentiation; GO:0001818 negative regulation of cytokine production; GO:0031400 negative regulation of protein modification process; GO:0040013 negative regulation of locomotion; GO:0031396 regulation of protein ubiquitination; GO:2001141 regulation of RNA biosynthetic process; GO:0051783 regulation of nuclear division; GO:0010646 regulation of cell communication; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0035303 regulation of dephosphorylation; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0010720 positive regulation of cell development; GO:0051726 regulation of cell cycle; GO:0032502 developmental process; GO:0055024 regulation of cardiac muscle tissue development; GO:0010468 regulation of gene expression; GO:0045937 positive regulation of phosphate metabolic process; GO:0048639 positive regulation of developmental growth; GO:0031326 regulation of cellular biosynthetic process; GO:0051098 regulation of binding; GO:0046622 positive regulation of organ growth; GO:0048522 positive regulation of cellular process; GO:0090257 regulation of muscle system process; GO:0048636 positive regulation of muscle organ development; GO:0010605 negative regulation of macromolecule metabolic process; GO:0010942 positive regulation of cell death; GO:0016202 regulation of striated muscle tissue development; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0051302 regulation of cell division; GO:0035306 positive regulation of dephosphorylation; GO:0051100 negative regulation of binding; GO:1900180 regulation of protein localization to nucleus; GO:0043087 regulation of GTPase activity; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0051271 negative regulation of cellular component movement; GO:2000026 regulation of multicellular organismal development; GO:0016043 cellular component organization; GO:1905209 positive regulation of cardiocyte differentiation; GO:0051155 positive regulation of striated muscle cell differentiation; GO:0032479 regulation of type I interferon production; GO:0043069 negative regulation of programmed cell death; GO:0040008 regulation of growth; GO:0042177 negative regulation of protein catabolic process; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:0060255 regulation of macromolecule metabolic process; GO:0017015 regulation of transforming growth factor beta receptor signaling pathway; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0043065 positive regulation of apoptotic process; GO:0055023 positive regulation of cardiac muscle tissue growth; GO:0031324 negative regulation of cellular metabolic process; GO:0048638 regulation of developmental growth; GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0032465 regulation of cytokinesis; GO:0071704 organic substance metabolic process; GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0043393 regulation of protein binding; GO:0030154 cell differentiation; GO:1903322 positive regulation of protein modification by small protein conjugation or removal; GO:1901216 positive regulation of neuron death; GO:0043066 negative regulation of apoptotic process; GO:0060393 regulation of pathway-restricted SMAD protein phosphorylation; GO:0043408 regulation of MAPK cascade; GO:0023056 positive regulation of signaling; GO:0042326 negative regulation of phosphorylation; GO:0090288 negative regulation of cellular response to growth factor stimulus; GO:1901796 regulation of signal transduction by p53 class mediator; GO:0009895 negative regulation of catabolic process; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:1901214 regulation of neuron death; GO:0045595 regulation of cell differentiation; GO:0006355 regulation of transcription, DNA-templated; GO:0035307 positive regulation of protein dephosphorylation; GO:1901861 regulation of muscle tissue development; GO:0001932 regulation of protein phosphorylation; GO:0033043 regulation of organelle organization; GO:0031401 positive regulation of protein modification process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway; GO:0048585 negative regulation of response to stimulus; GO:0018208 peptidyl-proline modification; GO:0001934 positive regulation of protein phosphorylation; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0060421 positive regulation of heart growth; GO:0051153 regulation of striated muscle cell differentiation; GO:0043085 positive regulation of catalytic activity; GO:0018193 peptidyl-amino acid modification; GO:1903844 regulation of cellular response to transforming growth factor beta stimulus; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0010563 negative regulation of phosphorus metabolic process; GO:0001817 regulation of cytokine production; GO:0051248 negative regulation of protein metabolic process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0051128 regulation of cellular component organization; GO:0009967 positive regulation of signal transduction; GO:0040012 regulation of locomotion; GO:0032480 negative regulation of type I interferon production; GO:0007049 cell cycle; GO:1905207 regulation of cardiocyte differentiation; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0030496 midbody; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0016604 nuclear body; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0005622 intracellular; GO:0044464 cell part; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0044451 nucleoplasm part; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0003755 peptidyl-prolyl cis-trans isomerase activity; GO:0031434 mitogen-activated protein kinase kinase binding; GO:0016597 amino acid binding; GO:0003774 motor activity; GO:0050815 phosphoserine binding; GO:0043167 ion binding; GO:0019901 protein kinase binding; GO:0043177 organic acid binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0045309 protein phosphorylated amino acid binding; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0017111 nucleoside-triphosphatase activity; GO:0019900 kinase binding; GO:0050816 phosphothreonine binding; GO:0032794 GTPase activating protein binding; GO:0051219 phosphoprotein binding; GO:0016853 isomerase activity; GO:0016462 pyrophosphatase activity; GO:0031406 carboxylic acid binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043168 anion binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0016859 cis-trans isomerase activity; GO:0019899 enzyme binding; GO:0008013 beta-catenin binding; GO:0036094 small molecule binding; ","K09578","PIN1; peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 [EC:5.2.1.8]","hsa04622 RIG-I-like receptor signaling pathway - Homo sapiens (human); ","IPR001202; IPR000297; ","\"WW domain; Peptidyl-prolyl cis-trans isomerase, PpiC-type; \"\r"]
["Q13557","Calcium/calmodulin-dependent protein kinase type II subunit delta OS=Homo sapiens OX=9606 GN=CAMK2D","CAMK2D",56.369,44.051,16.6,6,11,5,1.126,0.984,1.061,0.931,0.907,0.966,0.884,0.0474,"cytoplasm\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0010941 regulation of cell death; GO:0065008 regulation of biological quality; GO:0007166 cell surface receptor signaling pathway; GO:0014742 positive regulation of muscle hypertrophy; GO:1901897 regulation of relaxation of cardiac muscle; GO:0010766 negative regulation of sodium ion transport; GO:1902306 negative regulation of sodium ion transmembrane transport; GO:0071345 cellular response to cytokine stimulus; GO:0044237 cellular metabolic process; GO:0010469 regulation of receptor activity; GO:0001558 regulation of cell growth; GO:0061337 cardiac conduction; GO:0008152 metabolic process; GO:0014743 regulation of muscle hypertrophy; GO:0098900 regulation of action potential; GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction; GO:0051240 positive regulation of multicellular organismal process; GO:0065003 macromolecular complex assembly; GO:1901019 regulation of calcium ion transmembrane transporter activity; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0055065 metal ion homeostasis; GO:1903115 regulation of actin filament-based movement; GO:0044057 regulation of system process; GO:0018105 peptidyl-serine phosphorylation; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0007399 nervous system development; GO:0051051 negative regulation of transport; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0043269 regulation of ion transport; GO:0006941 striated muscle contraction; GO:0019932 second-messenger-mediated signaling; GO:2000649 regulation of sodium ion transmembrane transporter activity; GO:0031323 regulation of cellular metabolic process; GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; GO:0010666 positive regulation of cardiac muscle cell apoptotic process; GO:0032501 multicellular organismal process; GO:0006874 cellular calcium ion homeostasis; GO:1903779 regulation of cardiac conduction; GO:0034762 regulation of transmembrane transport; GO:0000165 MAPK cascade; GO:1903506 regulation of nucleic acid-templated transcription; GO:0010660 regulation of muscle cell apoptotic process; GO:0080135 regulation of cellular response to stress; GO:0051336 regulation of hydrolase activity; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:2001257 regulation of cation channel activity; GO:0006464 cellular protein modification process; GO:0003015 heart process; GO:0003013 circulatory system process; GO:0032412 regulation of ion transmembrane transporter activity; GO:0043068 positive regulation of programmed cell death; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0016310 phosphorylation; GO:0002028 regulation of sodium ion transport; GO:0018210 peptidyl-threonine modification; GO:0031399 regulation of protein modification process; GO:0043067 regulation of programmed cell death; GO:0044267 cellular protein metabolic process; GO:0080134 regulation of response to stress; GO:0010665 regulation of cardiac muscle cell apoptotic process; GO:0003254 regulation of membrane depolarization; GO:0048519 negative regulation of biological process; GO:0010663 positive regulation of striated muscle cell apoptotic process; GO:0032844 regulation of homeostatic process; GO:2000650 negative regulation of sodium ion transmembrane transporter activity; GO:0051239 regulation of multicellular organismal process; GO:0051259 protein oligomerization; GO:0060341 regulation of cellular localization; GO:0031063 regulation of histone deacetylation; GO:0019722 calcium-mediated signaling; GO:0086003 cardiac muscle cell contraction; GO:0051345 positive regulation of hydrolase activity; GO:0009889 regulation of biosynthetic process; GO:0018107 peptidyl-threonine phosphorylation; GO:0051171 regulation of nitrogen compound metabolic process; GO:0010959 regulation of metal ion transport; GO:0007275 multicellular organism development; GO:0050848 regulation of calcium-mediated signaling; GO:0009966 regulation of signal transduction; GO:0048878 chemical homeostasis; GO:0006461 protein complex assembly; GO:1904062 regulation of cation transmembrane transport; GO:0032409 regulation of transporter activity; GO:0023014 signal transduction by protein phosphorylation; GO:0034763 negative regulation of transmembrane transport; GO:1902531 regulation of intracellular signal transduction; GO:0051282 regulation of sequestering of calcium ion; GO:0006950 response to stress; GO:0043547 positive regulation of GTPase activity; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:1902275 regulation of chromatin organization; GO:0051924 regulation of calcium ion transport; GO:0032970 regulation of actin filament-based process; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0033044 regulation of chromosome organization; GO:0010611 regulation of cardiac muscle hypertrophy; GO:0034766 negative regulation of ion transmembrane transport; GO:0043502 regulation of muscle adaptation; GO:0006873 cellular ion homeostasis; GO:0006793 phosphorus metabolic process; GO:0010613 positive regulation of cardiac muscle hypertrophy; GO:0002027 regulation of heart rate; GO:0030029 actin filament-based process; GO:0006928 movement of cell or subcellular component; GO:0032469 endoplasmic reticulum calcium ion homeostasis; GO:1902305 regulation of sodium ion transmembrane transport; GO:0071248 cellular response to metal ion; GO:0043412 macromolecule modification; GO:0006955 immune response; GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling; GO:0030048 actin filament-based movement; GO:0003012 muscle system process; GO:0070252 actin-mediated cell contraction; GO:0072503 cellular divalent inorganic cation homeostasis; GO:0090311 regulation of protein deacetylation; GO:0018209 peptidyl-serine modification; GO:0023051 regulation of signaling; GO:0048869 cellular developmental process; GO:0071346 cellular response to interferon-gamma; GO:0044699 single-organism process; GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity; GO:0055119 relaxation of cardiac muscle; GO:0006796 phosphate-containing compound metabolic process; GO:0098901 regulation of cardiac muscle cell action potential; GO:0060333 interferon-gamma-mediated signaling pathway; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0055117 regulation of cardiac muscle contraction; GO:0046777 protein autophosphorylation; GO:0010035 response to inorganic substance; GO:0032413 negative regulation of ion transmembrane transporter activity; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0071822 protein complex subunit organization; GO:0050801 ion homeostasis; GO:0031326 regulation of cellular biosynthetic process; GO:0051279 regulation of release of sequestered calcium ion into cytosol; GO:0034097 response to cytokine; GO:0055074 calcium ion homeostasis; GO:0098771 inorganic ion homeostasis; GO:0010661 positive regulation of muscle cell apoptotic process; GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; GO:0035637 multicellular organismal signaling; GO:0019725 cellular homeostasis; GO:0048522 positive regulation of cellular process; GO:0022898 regulation of transmembrane transporter activity; GO:0090257 regulation of muscle system process; GO:0023052 signaling; GO:0010038 response to metal ion; GO:0006942 regulation of striated muscle contraction; GO:0010942 positive regulation of cell death; GO:0042391 regulation of membrane potential; GO:0010649 regulation of cell communication by electrical coupling; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:1900034 regulation of cellular response to heat; GO:0019222 regulation of metabolic process; GO:0071241 cellular response to inorganic substance; GO:0043087 regulation of GTPase activity; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0006952 defense response; GO:0036211 protein modification process; GO:0070271 protein complex biogenesis; GO:0072507 divalent inorganic cation homeostasis; GO:0048856 anatomical structure development; GO:0031056 regulation of histone modification; GO:0016043 cellular component organization; GO:0040008 regulation of growth; GO:2000021 regulation of ion homeostasis; GO:0060255 regulation of macromolecule metabolic process; GO:0030003 cellular cation homeostasis; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:1903522 regulation of blood circulation; GO:0071310 cellular response to organic substance; GO:0043065 positive regulation of apoptotic process; GO:0008016 regulation of heart contraction; GO:0060048 cardiac muscle contraction; GO:0050896 response to stimulus; GO:0055082 cellular chemical homeostasis; GO:0045087 innate immune response; GO:0086004 regulation of cardiac muscle cell contraction; GO:0071704 organic substance metabolic process; GO:0090075 relaxation of muscle; GO:0042592 homeostatic process; GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction; GO:0030154 cell differentiation; GO:0006936 muscle contraction; GO:0006468 protein phosphorylation; GO:0055080 cation homeostasis; GO:0086091 regulation of heart rate by cardiac conduction; GO:1903169 regulation of calcium ion transmembrane transport; GO:0032410 negative regulation of transporter activity; GO:0008015 blood circulation; GO:0051592 response to calcium ion; GO:0060047 heart contraction; GO:0009987 cellular process; GO:0019221 cytokine-mediated signaling pathway; GO:0006355 regulation of transcription, DNA-templated; GO:0003008 system process; GO:0043271 negative regulation of ion transport; GO:0035556 intracellular signal transduction; GO:0051049 regulation of transport; GO:0090279 regulation of calcium ion import; GO:0006937 regulation of muscle contraction; GO:0033043 regulation of organelle organization; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0071277 cellular response to calcium ion; GO:0010556 regulation of macromolecule biosynthetic process; GO:0034341 response to interferon-gamma; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0043085 positive regulation of catalytic activity; GO:0043933 macromolecular complex subunit organization; GO:0018193 peptidyl-amino acid modification; GO:1904063 negative regulation of cation transmembrane transport; GO:1901077 regulation of relaxation of muscle; GO:0010662 regulation of striated muscle cell apoptotic process; GO:0034765 regulation of ion transmembrane transport; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0010522 regulation of calcium ion transport into cytosol; GO:0002026 regulation of the force of heart contraction; GO:0006875 cellular metal ion homeostasis; GO:1901725 regulation of histone deacetylase activity; GO:0051128 regulation of cellular component organization; GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0016528 sarcoplasm; GO:0005623 cell; GO:0044422 organelle part; GO:0033017 sarcoplasmic reticulum membrane; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0043005 neuron projection; GO:0030139 endocytic vesicle; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0005789 endoplasmic reticulum membrane; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0098588 bounding membrane of organelle; GO:0030666 endocytic vesicle membrane; GO:0044446 intracellular organelle part; GO:0016529 sarcoplasmic reticulum; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0044432 endoplasmic reticulum part; GO:0042383 sarcolemma; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0008200 ion channel inhibitor activity; GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0005085 guanyl-nucleotide exchange factor activity; GO:0046983 protein dimerization activity; GO:0099106 ion channel regulator activity; GO:0005515 protein binding; GO:0017080 sodium channel regulator activity; GO:0004683 calmodulin-dependent protein kinase activity; GO:0004672 protein kinase activity; GO:0098772 molecular function regulator; GO:0016248 channel inhibitor activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0008092 cytoskeletal protein binding; GO:0042802 identical protein binding; GO:0016301 kinase activity; GO:0016247 channel regulator activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0019871 sodium channel inhibitor activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0005516 calmodulin binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0042803 protein homodimerization activity; GO:0044325 ion channel binding; GO:0005088 Ras guanyl-nucleotide exchange factor activity; GO:0004674 protein serine/threonine kinase activity; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0031432 titin binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0036094 small molecule binding; ","K04515","CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]","hsa04921 Oxytocin signaling pathway - Homo sapiens (human); hsa05152 Tuberculosis - Homo sapiens (human); hsa04728 Dopaminergic synapse - Homo sapiens (human); hsa04722 Neurotrophin signaling pathway - Homo sapiens (human); hsa05031 Amphetamine addiction - Homo sapiens (human); hsa04916 Melanogenesis - Homo sapiens (human); hsa04217 Necroptosis - Homo sapiens (human); hsa04020 Calcium signaling pathway - Homo sapiens (human); hsa04024 cAMP signaling pathway - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa04911 Insulin secretion - Homo sapiens (human); hsa04750 Inflammatory mediator regulation of TRP channels - Homo sapiens (human); hsa04114 Oocyte meiosis - Homo sapiens (human); hsa04925 Aldosterone synthesis and secretion - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa04740 Olfactory transduction - Homo sapiens (human); hsa04934 Cushing's syndrome - Homo sapiens (human); hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human); hsa04912 GnRH signaling pathway - Homo sapiens (human); hsa04066 HIF-1 signaling pathway - Homo sapiens (human); hsa04922 Glucagon signaling pathway - Homo sapiens (human); hsa05214 Glioma - Homo sapiens (human); hsa04012 ErbB signaling pathway - Homo sapiens (human); hsa04720 Long-term potentiation - Homo sapiens (human); hsa04971 Gastric acid secretion - Homo sapiens (human); hsa04360 Axon guidance - Homo sapiens (human); hsa04713 Circadian entrainment - Homo sapiens (human); hsa04310 Wnt signaling pathway - Homo sapiens (human); hsa04725 Cholinergic synapse - Homo sapiens (human); ","IPR000719; IPR013543; IPR011009; IPR032710; ","\"Protein kinase domain; Calcium/calmodulin-dependent protein kinase II, association-domain; Protein kinase-like domain; NTF2-like domain; \"\r"]
["Q13561","Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2","DCTN2",44.23,141.51,43.9,13,24,13,1.046,1.026,0.991,1.017,0.971,0.941,0.956,0.178,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0007067 mitotic nuclear division; GO:1905508 protein localization to microtubule organizing center; GO:0060271 cilium assembly; GO:0044699 single-organism process; GO:0044782 cilium organization; GO:0051234 establishment of localization; GO:0051875 pigment granule localization; GO:0051649 establishment of localization in cell; GO:0022607 cellular component assembly; GO:0032400 melanosome localization; GO:0044770 cell cycle phase transition; GO:0033365 protein localization to organelle; GO:0051904 pigment granule transport; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0044765 single-organism transport; GO:0000278 mitotic cell cycle; GO:0051650 establishment of vesicle localization; GO:0048002 antigen processing and presentation of peptide antigen; GO:0044763 single-organism cellular process; GO:0002495 antigen processing and presentation of peptide antigen via MHC class II; GO:1902582 single-organism intracellular transport; GO:0006810 transport; GO:0000226 microtubule cytoskeleton organization; GO:0019884 antigen processing and presentation of exogenous antigen; GO:1902589 single-organism organelle organization; GO:0044380 protein localization to cytoskeleton; GO:0072698 protein localization to microtubule cytoskeleton; GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; GO:0030030 cell projection organization; GO:1902850 microtubule cytoskeleton organization involved in mitosis; GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II; GO:0071539 protein localization to centrosome; GO:0000086 G2/M transition of mitotic cell cycle; GO:0051640 organelle localization; GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0048285 organelle fission; GO:0048193 Golgi vesicle transport; GO:0007051 spindle organization; GO:0097711 ciliary basal body docking; GO:1903047 mitotic cell cycle process; GO:0022406 membrane docking; GO:1902578 single-organism localization; GO:0070925 organelle assembly; GO:0051905 establishment of pigment granule localization; GO:0051648 vesicle localization; GO:1902580 single-organism cellular localization; GO:0032402 melanosome transport; GO:0007052 mitotic spindle organization; GO:0007010 cytoskeleton organization; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0044772 mitotic cell cycle phase transition; GO:0016192 vesicle-mediated transport; GO:0008283 cell proliferation; GO:0002376 immune system process; GO:0051656 establishment of organelle localization; GO:0007017 microtubule-based process; GO:0030031 cell projection assembly; GO:0051641 cellular localization; GO:0019882 antigen processing and presentation; GO:0070727 cellular macromolecule localization; GO:0006996 organelle organization; GO:0000280 nuclear division; GO:0043473 pigmentation; GO:0032401 establishment of melanosome localization; GO:0044839 cell cycle G2/M phase transition; GO:0022402 cell cycle process; GO:0051179 localization; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0033059 cellular pigmentation; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005874 microtubule; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0005869 dynactin complex; GO:0030426 growth cone; GO:0044424 intracellular part; GO:0099512 supramolecular fiber; GO:0005623 cell; GO:0099080 supramolecular complex; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005856 cytoskeleton; GO:0005815 microtubule organizing center; GO:1902494 catalytic complex; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0000776 kinetochore; GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0030286 dynein complex; GO:0005875 microtubule associated complex; GO:0005829 cytosol; GO:0030427 site of polarized growth; GO:0044463 cell projection part; GO:0005576 extracellular region; GO:0015629 actin cytoskeleton; GO:0099081 supramolecular polymer; GO:0098687 chromosomal region; GO:0043226 organelle; GO:0005813 centrosome; GO:0000775 chromosome, centromeric region; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0042802 identical protein binding; GO:0008092 cytoskeletal protein binding; GO:0003774 motor activity; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017111 nucleoside-triphosphatase activity; GO:0030507 spectrin binding; ","K10424","DCTN2; dynactin 2","hsa05016 Huntington's disease - Homo sapiens (human); hsa04962 Vasopressin-regulated water reabsorption - Homo sapiens (human); "]
["Q13576","Ras GTPase-activating-like protein IQGAP2 OS=Homo sapiens OX=9606 GN=IQGAP2","IQGAP2",180.58,118.97,16.3,23,35,22,1.058,1.064,1.087,0.926,0.921,0.932,0.866,8.33e-05,"nucleus\r","GO:0044700 single organism signaling; GO:0030833 regulation of actin filament polymerization; GO:0034314 Arp2/3 complex-mediated actin nucleation; GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0032273 positive regulation of protein polymerization; GO:0044699 single-organism process; GO:0030832 regulation of actin filament length; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0007165 signal transduction; GO:0030036 actin cytoskeleton organization; GO:0007154 cell communication; GO:0045010 actin nucleation; GO:0032535 regulation of cellular component size; GO:0032271 regulation of protein polymerization; GO:0031334 positive regulation of protein complex assembly; GO:0051493 regulation of cytoskeleton organization; GO:0034260 negative regulation of GTPase activity; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0043086 negative regulation of catalytic activity; GO:0023052 signaling; GO:0002444 myeloid leukocyte mediated immunity; GO:0006810 transport; GO:1902589 single-organism organelle organization; GO:0043254 regulation of protein complex assembly; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:0010638 positive regulation of organelle organization; GO:0050790 regulation of catalytic activity; GO:0032940 secretion by cell; GO:0043087 regulation of GTPase activity; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:1902905 positive regulation of supramolecular fiber organization; GO:0043299 leukocyte degranulation; GO:0097435 supramolecular fiber organization; GO:0070493 thrombin-activated receptor signaling pathway; GO:1902903 regulation of supramolecular fiber organization; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0032956 regulation of actin cytoskeleton organization; GO:0007015 actin filament organization; GO:0044087 regulation of cellular component biogenesis; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0051346 negative regulation of hydrolase activity; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0036230 granulocyte activation; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0051495 positive regulation of cytoskeleton organization; GO:0016192 vesicle-mediated transport; GO:0033043 regulation of organelle organization; GO:0032970 regulation of actin filament-based process; GO:0002376 immune system process; GO:0043312 neutrophil degranulation; GO:0030838 positive regulation of actin filament polymerization; GO:0048518 positive regulation of biological process; GO:0002263 cell activation involved in immune response; GO:0007186 G-protein coupled receptor signaling pathway; GO:0002366 leukocyte activation involved in immune response; GO:0008064 regulation of actin polymerization or depolymerization; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0001775 cell activation; GO:0090066 regulation of anatomical structure size; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0006955 immune response; GO:0044089 positive regulation of cellular component biogenesis; GO:0006887 exocytosis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005874 microtubule; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0098858 actin-based cell projection; GO:0005623 cell; GO:0099080 supramolecular complex; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005856 cytoskeleton; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0099503 secretory vesicle; GO:0030027 lamellipodium; GO:1903561 extracellular vesicle; GO:0030175 filopodium; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0031252 cell leading edge; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0099513 polymeric cytoskeletal fiber; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0015629 actin cytoskeleton; GO:0005576 extracellular region; GO:0099081 supramolecular polymer; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0030667 secretory granule membrane; GO:0005902 microvillus; GO:0009986 cell surface; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0031267 small GTPase binding; GO:0051015 actin filament binding; GO:1901981 phosphatidylinositol phosphate binding; GO:0017048 Rho GTPase binding; GO:0048365 Rac GTPase binding; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0071933 Arp2/3 complex binding; GO:0043167 ion binding; GO:0030695 GTPase regulator activity; GO:0044877 macromolecular complex binding; GO:0005515 protein binding; GO:0005095 GTPase inhibitor activity; GO:0098772 molecular function regulator; GO:0004857 enzyme inhibitor activity; GO:0005516 calmodulin binding; GO:0008092 cytoskeletal protein binding; GO:0030234 enzyme regulator activity; GO:0017016 Ras GTPase binding; GO:0005488 binding; GO:0005543 phospholipid binding; GO:0035091 phosphatidylinositol binding; GO:0008289 lipid binding; GO:0003779 actin binding; GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding; GO:0043168 anion binding; GO:0051020 GTPase binding; GO:0019899 enzyme binding; GO:0032403 protein complex binding; ","K05767","IQGAP2_3; Ras GTPase-activating-like protein IQGAP2/3","hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); ","IPR001936; IPR001202; IPR001715; IPR000593; IPR008936; ","\"Ras GTPase-activating protein; WW domain; Calponin homology domain; RasGAP protein, C-terminal; Rho GTPase activation protein; \"\r"]
["Q13596","Sorting nexin-1 OS=Homo sapiens OX=9606 GN=SNX1","SNX1",59.069,75.74,34.9,16,23,14,1.009,1.013,1.05,0.982,0.991,0.976,0.96,0.0386,"cytoplasm\r","GO:0097581 lamellipodium organization; GO:0031623 receptor internalization; GO:0048869 cellular developmental process; GO:0032989 cellular component morphogenesis; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0072673 lamellipodium morphogenesis; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0009893 positive regulation of metabolic process; GO:0032990 cell part morphogenesis; GO:0048858 cell projection morphogenesis; GO:0043170 macromolecule metabolic process; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0044765 single-organism transport; GO:0032502 developmental process; GO:0043112 receptor metabolic process; GO:0080090 regulation of primary metabolic process; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0016197 endosomal transport; GO:0006810 transport; GO:0000902 cell morphogenesis; GO:0050789 regulation of biological process; GO:0042147 retrograde transport, endosome to Golgi; GO:0030030 cell projection organization; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0048856 anatomical structure development; GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0060255 regulation of macromolecule metabolic process; GO:0048193 Golgi vesicle transport; GO:0071704 organic substance metabolic process; GO:0009653 anatomical structure morphogenesis; GO:1902578 single-organism localization; GO:0009896 positive regulation of catabolic process; GO:0006886 intracellular protein transport; GO:0006898 receptor-mediated endocytosis; GO:0042176 regulation of protein catabolic process; GO:0034613 cellular protein localization; GO:0016482 cytosolic transport; GO:0009987 cellular process; GO:0016192 vesicle-mediated transport; GO:0016050 vesicle organization; GO:0071702 organic substance transport; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0051247 positive regulation of protein metabolic process; GO:0034498 early endosome to Golgi transport; GO:0044767 single-organism developmental process; GO:0006996 organelle organization; GO:0051246 regulation of protein metabolic process; GO:0045732 positive regulation of protein catabolic process; GO:0051179 localization; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0030904 retromer complex; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0019898 extrinsic component of membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0098805 whole membrane; GO:0005764 lysosome; GO:0030027 lamellipodium; GO:0005768 endosome; GO:0031901 early endosome membrane; GO:0043227 membrane-bounded organelle; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0031252 cell leading edge; GO:0010008 endosome membrane; GO:0042995 cell projection; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0044440 endosomal part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005773 vacuole; GO:0030905 retromer, tubulation complex; GO:0005794 Golgi apparatus; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0046982 protein heterodimerization activity; GO:0005102 receptor binding; GO:0046983 protein dimerization activity; GO:0043167 ion binding; GO:0044877 macromolecular complex binding; GO:0070851 growth factor receptor binding; GO:0005515 protein binding; GO:1990460 leptin receptor binding; GO:0005158 insulin receptor binding; GO:0050839 cell adhesion molecule binding; GO:0042802 identical protein binding; GO:0005154 epidermal growth factor receptor binding; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0045296 cadherin binding; GO:0005543 phospholipid binding; GO:0035091 phosphatidylinositol binding; GO:0008289 lipid binding; GO:0043168 anion binding; GO:1990459 transferrin receptor binding; GO:0032403 protein complex binding; ","K17917","SNX1_2; sorting nexin-1/2","hsa04144 Endocytosis - Homo sapiens (human); ","IPR015404; IPR005329; IPR001683; ","\"Sorting nexin Vps5-like, C-terminal; Sorting nexin, N-terminal; Phox homologous domain; \"\r"]
["Q13620","Cullin-4B OS=Homo sapiens OX=9606 GN=CUL4B","CUL4B",103.98,6.549,9.7,10,13,4,1.111,1.001,1.037,1.023,0.886,0.96,0.911,0.143,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion; GO:0006289 nucleotide-excision repair; GO:0034644 cellular response to UV; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0065003 macromolecular complex assembly; GO:0051606 detection of stimulus; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0090068 positive regulation of cell cycle process; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0071214 cellular response to abiotic stimulus; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0016574 histone ubiquitination; GO:0032501 multicellular organismal process; GO:0071482 cellular response to light stimulus; GO:0065004 protein-DNA complex assembly; GO:1901575 organic substance catabolic process; GO:0045931 positive regulation of mitotic cell cycle; GO:0030163 protein catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0090305 nucleic acid phosphodiester bond hydrolysis; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0044707 single-multicellular organism process; GO:0007346 regulation of mitotic cell cycle; GO:0006283 transcription-coupled nucleotide-excision repair; GO:0009628 response to abiotic stimulus; GO:0006259 DNA metabolic process; GO:0016570 histone modification; GO:0044267 cellular protein metabolic process; GO:1901989 positive regulation of cell cycle phase transition; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901987 regulation of cell cycle phase transition; GO:0009896 positive regulation of catabolic process; GO:0044248 cellular catabolic process; GO:0042176 regulation of protein catabolic process; GO:0016569 covalent chromatin modification; GO:0007275 multicellular organism development; GO:0070914 UV-damage excision repair; GO:0045787 positive regulation of cell cycle; GO:0009416 response to light stimulus; GO:0006950 response to stress; GO:0016567 protein ubiquitination; GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0048731 system development; GO:0044238 primary metabolic process; GO:0006974 cellular response to DNA damage stimulus; GO:1900087 positive regulation of G1/S transition of mitotic cell cycle; GO:0030182 neuron differentiation; GO:0051247 positive regulation of protein metabolic process; GO:0033522 histone H2A ubiquitination; GO:0032446 protein modification by small protein conjugation; GO:0051276 chromosome organization; GO:0006996 organelle organization; GO:0006294 nucleotide-excision repair, preincision complex assembly; GO:0043412 macromolecule modification; GO:2000045 regulation of G1/S transition of mitotic cell cycle; GO:0048869 cellular developmental process; GO:0048666 neuron development; GO:0032392 DNA geometric change; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0051130 positive regulation of cellular component organization; GO:0022607 cellular component assembly; GO:0009893 positive regulation of metabolic process; GO:1902806 regulation of cell cycle G1/S phase transition; GO:0009314 response to radiation; GO:0031334 positive regulation of protein complex assembly; GO:0051726 regulation of cell cycle; GO:0071103 DNA conformation change; GO:0071824 protein-DNA complex subunit organization; GO:0032502 developmental process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0000715 nucleotide-excision repair, DNA damage recognition; GO:0043254 regulation of protein complex assembly; GO:0050789 regulation of biological process; GO:0006513 protein monoubiquitination; GO:0090304 nucleic acid metabolic process; GO:0030030 cell projection organization; GO:0019222 regulation of metabolic process; GO:0006325 chromatin organization; GO:0036211 protein modification process; GO:1902808 positive regulation of cell cycle G1/S phase transition; GO:0048856 anatomical structure development; GO:0016043 cellular component organization; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion; GO:0060255 regulation of macromolecule metabolic process; GO:0044087 regulation of cellular component biogenesis; GO:0042769 DNA damage response, detection of DNA damage; GO:0050896 response to stimulus; GO:0033683 nucleotide-excision repair, DNA incision; GO:0048468 cell development; GO:0006293 nucleotide-excision repair, preincision complex stabilization; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0070911 global genome nucleotide-excision repair; GO:0006508 proteolysis; GO:0034641 cellular nitrogen compound metabolic process; GO:0071478 cellular response to radiation; GO:0009987 cellular process; GO:0043632 modification-dependent macromolecule catabolic process; GO:0010390 histone monoubiquitination; GO:0034622 cellular macromolecular complex assembly; GO:0044265 cellular macromolecule catabolic process; GO:0019941 modification-dependent protein catabolic process; GO:0000717 nucleotide-excision repair, DNA duplex unwinding; GO:0032508 DNA duplex unwinding; GO:0006807 nitrogen compound metabolic process; GO:0031175 neuron projection development; GO:0048518 positive regulation of biological process; GO:0043933 macromolecular complex subunit organization; GO:0006281 DNA repair; GO:0035518 histone H2A monoubiquitination; GO:0009411 response to UV; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0009057 macromolecule catabolic process; GO:0045732 positive regulation of protein catabolic process; GO:0051128 regulation of cellular component organization; GO:0009056 catabolic process; GO:1901992 positive regulation of mitotic cell cycle phase transition; GO:0007049 cell cycle; GO:0044089 positive regulation of cellular component biogenesis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0080008 Cul4-RING E3 ubiquitin ligase complex; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0000151 ubiquitin ligase complex; GO:0031465 Cul4B-RING E3 ubiquitin ligase complex; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0031461 cullin-RING ubiquitin ligase complex; GO:0031981 nuclear lumen; GO:1990234 transferase complex; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0031625 ubiquitin protein ligase binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0005488 binding; GO:0019899 enzyme binding; ","K10609","CUL4; cullin 4","hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human); hsa03420 Nucleotide excision repair - Homo sapiens (human); ","IPR011991; IPR016158; IPR019559; IPR001373; IPR016159; ","\"Winged helix-turn-helix DNA-binding domain; Cullin homology; Cullin protein, neddylation domain; Cullin, N-terminal; Cullin repeat-like-containing domain; \"\r"]
["Q13630","GDP-L-fucose synthase OS=Homo sapiens OX=9606 GN=TSTA3","TSTA3",35.892,116.59,31.8,9,15,9,0.893,0.98,0.903,1.03,1.066,1.031,1.126,0.0189,"cytoplasm\r","GO:0009226 nucleotide-sugar biosynthetic process; GO:0007159 leukocyte cell-cell adhesion; GO:0019835 cytolysis; GO:0006725 cellular aromatic compound metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0022610 biological adhesion; GO:0016337 single organismal cell-cell adhesion; GO:0008152 metabolic process; GO:0019673 GDP-mannose metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0007155 cell adhesion; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009987 cellular process; GO:0018130 heterocycle biosynthetic process; GO:0055114 oxidation-reduction process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0098609 cell-cell adhesion; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0046368 GDP-L-fucose metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0098602 single organism cell adhesion; GO:0042350 GDP-L-fucose biosynthetic process; GO:0009225 nucleotide-sugar metabolic process; GO:0042351 'de novo' GDP-L-fucose biosynthetic process; GO:1901362 organic cyclic compound biosynthetic process; ","GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0009055 electron carrier activity; GO:0016614 oxidoreductase activity, acting on CH-OH group of donors; GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; GO:0042802 identical protein binding; GO:0016853 isomerase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0050577 GDP-L-fucose synthase activity; GO:0005515 protein binding; GO:0042356 GDP-4-dehydro-D-rhamnose reductase activity; GO:0048037 cofactor binding; GO:0050662 coenzyme binding; GO:0016491 oxidoreductase activity; ","K02377","TSTA3; GDP-L-fucose synthase [EC:1.1.1.271]","hsa00051 Fructose and mannose metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00520 Amino sugar and nucleotide sugar metabolism - Homo sapiens (human); ","IPR001509; IPR016040; ","NAD-dependent epimerase/dehydratase; NAD(P)-binding domain; \r"]
["Q13643","Four and a half LIM domains protein 3 OS=Homo sapiens OX=9606 GN=FHL3","FHL3",31.192,7.2034,12.1,3,3,3,0.981,1.048,1.009,0.977,0.957,0.92,0.939,0.0745,"nucleus\r","GO:0032502 developmental process; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0048731 system development; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0032501 multicellular organismal process; GO:1902589 single-organism organelle organization; GO:0030036 actin cytoskeleton organization; GO:0048513 animal organ development; GO:0007517 muscle organ development; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0030029 actin filament-based process; GO:0061061 muscle structure development; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0048856 anatomical structure development; GO:0009987 cellular process; GO:0071840 cellular component organization or biogenesis; ","GO:0030054 cell junction; GO:0030016 myofibril; GO:0005737 cytoplasm; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0030018 Z disc; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0031674 I band; GO:0044422 organelle part; GO:0032432 actin filament bundle; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0044464 cell part; GO:0043292 contractile fiber; GO:0005912 adherens junction; GO:0001725 stress fiber; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0042641 actomyosin; GO:0005924 cell-substrate adherens junction; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0097517 contractile actin filament bundle; GO:0015629 actin cytoskeleton; GO:0099081 supramolecular polymer; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0030017 sarcomere; GO:0044449 contractile fiber part; GO:0044444 cytoplasmic part; ","GO:0008092 cytoskeletal protein binding; GO:0046914 transition metal ion binding; GO:0005488 binding; GO:0043167 ion binding; GO:0003779 actin binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0008270 zinc ion binding; ",{"$nulls":3},"IPR001781; ","\"Zinc finger, LIM-type; \"\r"]
["Q13671","Ras and Rab interactor 1 OS=Homo sapiens OX=9606 GN=RIN1","RIN1",84.098,4.6261,2,1,1,1,0.907,1.021,0.924,1.086,0.945,1.122,1.106,0.198,"nucleus\r","GO:0044700 single organism signaling; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0065008 regulation of biological quality; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0031914 negative regulation of synaptic plasticity; GO:0050896 response to stimulus; GO:0050877 neurological system process; GO:0051234 establishment of localization; GO:0007610 behavior; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0051345 positive regulation of hydrolase activity; GO:0044093 positive regulation of molecular function; GO:0050890 cognition; GO:0009987 cellular process; GO:0048167 regulation of synaptic plasticity; GO:0051716 cellular response to stimulus; GO:0003008 system process; GO:0043547 positive regulation of GTPase activity; GO:0050804 modulation of synaptic transmission; GO:0016192 vesicle-mediated transport; GO:0006897 endocytosis; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0007611 learning or memory; GO:0043085 positive regulation of catalytic activity; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:0007612 learning; GO:0050790 regulation of catalytic activity; GO:0061024 membrane organization; GO:0007613 memory; GO:0065009 regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0008306 associative learning; GO:0051179 localization; GO:0044708 single-organism behavior; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0030425 dendrite; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0043025 neuronal cell body; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005886 plasma membrane; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0044464 cell part; GO:0005622 intracellular; GO:0043005 neuron projection; GO:0044297 cell body; GO:0097458 neuron part; GO:0044444 cytoplasmic part; ","GO:0031267 small GTPase binding; GO:0030234 enzyme regulator activity; GO:0017112 Rab guanyl-nucleotide exchange factor activity; GO:0005085 guanyl-nucleotide exchange factor activity; GO:0017016 Ras GTPase binding; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0005488 binding; GO:0030695 GTPase regulator activity; GO:0005515 protein binding; GO:0005088 Ras guanyl-nucleotide exchange factor activity; GO:0098772 molecular function regulator; GO:0051020 GTPase binding; GO:0008047 enzyme activator activity; GO:0019899 enzyme binding; GO:0005096 GTPase activator activity; ","K17638","RIN1; Ras and Rab interactor 1","hsa04014 Ras signaling pathway - Homo sapiens (human); ","IPR000980; IPR003123; IPR000159; ","SH2 domain; VPS9 domain; Ras-associating (RA) domain; \r"]
["Q13765","Nascent polypeptide-associated complex subunit alpha OS=Homo sapiens OX=9606 GN=NACA","NACA",23.384,71.348,19.5,3,9,3,0.81,0.841,0.842,1.113,1.165,1.163,1.38,8.03E-5,"cytoplasm\r","GO:0010941 regulation of cell death; GO:0006518 peptide metabolic process; GO:0097659 nucleic acid-templated transcription; GO:0009891 positive regulation of biosynthetic process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0045927 positive regulation of growth; GO:0008152 metabolic process; GO:0007507 heart development; GO:0048742 regulation of skeletal muscle fiber development; GO:0051240 positive regulation of multicellular organismal process; GO:0010830 regulation of myotube differentiation; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0044419 interspecies interaction between organisms; GO:0008104 protein localization; GO:0051147 regulation of muscle cell differentiation; GO:0018130 heterocycle biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0000122 negative regulation of transcription from RNA polymerase II promoter; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032774 RNA biosynthetic process; GO:2000826 regulation of heart morphogenesis; GO:0031323 regulation of cellular metabolic process; GO:0061383 trabecula morphogenesis; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0006810 transport; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0010660 regulation of muscle cell apoptotic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:1901213 regulation of transcription from RNA polymerase II promoter involved in heart development; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:1901863 positive regulation of muscle tissue development; GO:0051094 positive regulation of developmental process; GO:0060548 negative regulation of cell death; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0048641 regulation of skeletal muscle tissue development; GO:0050794 regulation of cellular process; GO:0072359 circulatory system development; GO:0044707 single-multicellular organism process; GO:0042127 regulation of cell proliferation; GO:0044267 cellular protein metabolic process; GO:0043067 regulation of programmed cell death; GO:1901227 negative regulation of transcription from RNA polymerase II promoter involved in heart development; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0051239 regulation of multicellular organismal process; GO:0061384 heart trabecula morphogenesis; GO:0045892 negative regulation of transcription, DNA-templated; GO:0009653 anatomical structure morphogenesis; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0045844 positive regulation of striated muscle tissue development; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0007275 multicellular organism development; GO:0003231 cardiac ventricle development; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0051254 positive regulation of RNA metabolic process; GO:0006950 response to stress; GO:0048731 system development; GO:0060284 regulation of cell development; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0045184 establishment of protein localization; GO:0009890 negative regulation of biosynthetic process; GO:0031325 positive regulation of cellular metabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0051179 localization; GO:0048589 developmental growth; GO:0050793 regulation of developmental process; GO:0040007 growth; GO:1901564 organonitrogen compound metabolic process; GO:0008284 positive regulation of cell proliferation; GO:0048634 regulation of muscle organ development; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0051253 negative regulation of RNA metabolic process; GO:0051234 establishment of localization; GO:0009611 response to wounding; GO:2001141 regulation of RNA biosynthetic process; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0006412 translation; GO:0033036 macromolecule localization; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0048639 positive regulation of developmental growth; GO:0009888 tissue development; GO:0031326 regulation of cellular biosynthetic process; GO:0043043 peptide biosynthetic process; GO:0042246 tissue regeneration; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0048636 positive regulation of muscle organ development; GO:0010605 negative regulation of macromolecule metabolic process; GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis; GO:0016070 RNA metabolic process; GO:0016202 regulation of striated muscle tissue development; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:1902679 negative regulation of RNA biosynthetic process; GO:0019222 regulation of metabolic process; GO:0048643 positive regulation of skeletal muscle tissue development; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0048631 regulation of skeletal muscle tissue growth; GO:0040008 regulation of growth; GO:0043069 negative regulation of programmed cell death; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0048638 regulation of developmental growth; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:2000027 regulation of organ morphogenesis; GO:0043066 negative regulation of apoptotic process; GO:0016032 viral process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0043403 skeletal muscle tissue regeneration; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:1901861 regulation of muscle tissue development; GO:0010664 negative regulation of striated muscle cell apoptotic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:2000136 regulation of cell proliferation involved in heart morphogenesis; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0010656 negative regulation of muscle cell apoptotic process; GO:0044249 cellular biosynthetic process; GO:0003205 cardiac chamber development; GO:0051153 regulation of striated muscle cell differentiation; GO:0010662 regulation of striated muscle cell apoptotic process; GO:0042060 wound healing; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:1901228 positive regulation of transcription from RNA polymerase II promoter involved in heart development; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0048633 positive regulation of skeletal muscle tissue growth; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0031099 regeneration; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0005854 nascent polypeptide-associated complex; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003677 DNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0003713 transcription coactivator activity; GO:0005515 protein binding; GO:0003712 transcription cofactor activity; GO:0000988 transcription factor activity, protein binding; ","K03626","EGD2; nascent polypeptide-associated complex subunit alpha","hsa04928 Parathyroid hormone synthesis, secretion and action - Homo sapiens (human); ","IPR002715; ","Nascent polypeptide-associated complex NAC domain; \r"]
["Q13822","Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 OS=Homo sapiens OX=9606 GN=ENPP2","ENPP2",98.993,11.483,4.6,4,4,4,1.114,1.12,0.958,0.887,0.993,0.946,0.885,0.119,"extracellular\r","GO:0044700 single organism signaling; GO:0046470 phosphatidylcholine metabolic process; GO:0030335 positive regulation of cell migration; GO:0046486 glycerolipid metabolic process; GO:0032270 positive regulation of cellular protein metabolic process; GO:0040017 positive regulation of locomotion; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0009395 phospholipid catabolic process; GO:0009605 response to external stimulus; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0007154 cell communication; GO:0051240 positive regulation of multicellular organismal process; GO:0009893 positive regulation of metabolic process; GO:0032879 regulation of localization; GO:0006650 glycerophospholipid metabolic process; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0043170 macromolecule metabolic process; GO:0006629 lipid metabolic process; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0045937 positive regulation of phosphate metabolic process; GO:0010632 regulation of epithelial cell migration; GO:2000394 positive regulation of lamellipodium morphogenesis; GO:0080090 regulation of primary metabolic process; GO:0031346 positive regulation of cell projection organization; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0051272 positive regulation of cellular component movement; GO:0023052 signaling; GO:0031323 regulation of cellular metabolic process; GO:0006935 chemotaxis; GO:0006810 transport; GO:1902745 positive regulation of lamellipodium organization; GO:1901575 organic substance catabolic process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0090304 nucleic acid metabolic process; GO:0044710 single-organism metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0045765 regulation of angiogenesis; GO:0042330 taxis; GO:0040011 locomotion; GO:0019220 regulation of phosphate metabolic process; GO:0090305 nucleic acid phosphodiester bond hydrolysis; GO:0051094 positive regulation of developmental process; GO:2000392 regulation of lamellipodium morphogenesis; GO:0046503 glycerolipid catabolic process; GO:2000026 regulation of multicellular organismal development; GO:0050794 regulation of cellular process; GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation; GO:0006725 cellular aromatic compound metabolic process; GO:0050730 regulation of peptidyl-tyrosine phosphorylation; GO:0046434 organophosphate catabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0031399 regulation of protein modification process; GO:0097164 ammonium ion metabolic process; GO:0031344 regulation of cell projection organization; GO:2000147 positive regulation of cell motility; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:1902743 regulation of lamellipodium organization; GO:0006139 nucleobase-containing compound metabolic process; GO:0046475 glycerophospholipid catabolic process; GO:2000145 regulation of cell motility; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0006898 receptor-mediated endocytosis; GO:0009987 cellular process; GO:0016042 lipid catabolic process; GO:0051270 regulation of cellular component movement; GO:0044712 single-organism catabolic process; GO:0016192 vesicle-mediated transport; GO:1901342 regulation of vasculature development; GO:0001932 regulation of protein phosphorylation; GO:0006807 nitrogen compound metabolic process; GO:0031401 positive regulation of protein modification process; GO:0002376 immune system process; GO:0030334 regulation of cell migration; GO:0010634 positive regulation of epithelial cell migration; GO:0001934 positive regulation of protein phosphorylation; GO:0044238 primary metabolic process; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0007186 G-protein coupled receptor signaling pathway; GO:1901565 organonitrogen compound catabolic process; GO:0051247 positive regulation of protein metabolic process; GO:0006793 phosphorus metabolic process; GO:0051246 regulation of protein metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0006928 movement of cell or subcellular component; GO:0019637 organophosphate metabolic process; GO:0044242 cellular lipid catabolic process; GO:0034638 phosphatidylcholine catabolic process; GO:0051128 regulation of cellular component organization; GO:0006644 phospholipid metabolic process; GO:0006955 immune response; GO:0040012 regulation of locomotion; GO:0051179 localization; GO:0022604 regulation of cell morphogenesis; GO:0050793 regulation of developmental process; GO:0009056 catabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0031226 intrinsic component of plasma membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0044459 plasma membrane part; GO:0044425 membrane part; GO:0044464 cell part; GO:0071944 cell periphery; GO:0031224 intrinsic component of membrane; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; ","GO:0004551 nucleotide diphosphatase activity; GO:0052689 carboxylic ester hydrolase activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0038024 cargo receptor activity; GO:0005515 protein binding; GO:0005044 scavenger receptor activity; GO:0016787 hydrolase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0030247 polysaccharide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0004622 lysophospholipase activity; GO:0004620 phospholipase activity; GO:0043169 cation binding; GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0001871 pattern binding; GO:0043167 ion binding; GO:0016298 lipase activity; GO:0008270 zinc ion binding; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0046914 transition metal ion binding; GO:0042578 phosphoric ester hydrolase activity; GO:0016788 hydrolase activity, acting on ester bonds; GO:0003676 nucleic acid binding; GO:0004518 nuclease activity; GO:0004527 exonuclease activity; GO:0030246 carbohydrate binding; GO:0046872 metal ion binding; GO:0008081 phosphoric diester hydrolase activity; GO:0005509 calcium ion binding; GO:0004528 phosphodiesterase I activity; GO:0008134 transcription factor binding; ","K01122","ENPP2; ectonucleotide pyrophosphatase/phosphodiesterase family member 2 [EC:3.1.4.39]","hsa00565 Ether lipid metabolism - Homo sapiens (human); ","IPR017849; IPR020821; IPR017850; IPR001604; IPR020436; IPR001212; ","\"Alkaline phosphatase-like, alpha/beta/alpha; Extracellular Endonuclease, subunit A; Alkaline-phosphatase-like, core domain; DNA/RNA non-specific endonuclease; Somatomedin B, chordata; Somatomedin B domain; \"\r"]
["Q13838","Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B","DDX39B",48.991,49.508,24.3,11,19,5,0.941,0.934,1.034,1.044,1.03,1.044,1.072,0.167,"cyto_nucl\r","GO:0044085 cellular component biogenesis; GO:0050658 RNA transport; GO:0022613 ribonucleoprotein complex biogenesis; GO:0048732 gland development; GO:0032270 positive regulation of cellular protein metabolic process; GO:0022618 ribonucleoprotein complex assembly; GO:0097659 nucleic acid-templated transcription; GO:0010608 posttranscriptional regulation of gene expression; GO:0009891 positive regulation of biosynthetic process; GO:0014742 positive regulation of muscle hypertrophy; GO:0051169 nuclear transport; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0045927 positive regulation of growth; GO:0001558 regulation of cell growth; GO:1902583 multi-organism intracellular transport; GO:0061050 regulation of cell growth involved in cardiac muscle cell development; GO:0008152 metabolic process; GO:0014743 regulation of muscle hypertrophy; GO:0051240 positive regulation of multicellular organismal process; GO:0065003 macromolecular complex assembly; GO:0015931 nucleobase-containing compound transport; GO:0032784 regulation of DNA-templated transcription, elongation; GO:0044057 regulation of system process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0075733 intracellular transport of virus; GO:0008104 protein localization; GO:2000727 positive regulation of cardiac muscle cell differentiation; GO:0051147 regulation of muscle cell differentiation; GO:0006396 RNA processing; GO:0018130 heterocycle biosynthetic process; GO:0055025 positive regulation of cardiac muscle tissue development; GO:0051054 positive regulation of DNA metabolic process; GO:0080090 regulation of primary metabolic process; GO:0030307 positive regulation of cell growth; GO:1901977 negative regulation of cell cycle checkpoint; GO:0045893 positive regulation of transcription, DNA-templated; GO:0032786 positive regulation of DNA-templated transcription, elongation; GO:0032774 RNA biosynthetic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0006611 protein export from nucleus; GO:0051704 multi-organism process; GO:0006810 transport; GO:1903506 regulation of nucleic acid-templated transcription; GO:2001021 negative regulation of response to DNA damage stimulus; GO:0048513 animal organ development; GO:0080135 regulation of cellular response to stress; GO:2000002 negative regulation of DNA damage checkpoint; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051149 positive regulation of muscle cell differentiation; GO:0006913 nucleocytoplasmic transport; GO:1904705 regulation of vascular smooth muscle cell proliferation; GO:0051094 positive regulation of developmental process; GO:1901863 positive regulation of muscle tissue development; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0046907 intracellular transport; GO:0042127 regulation of cell proliferation; GO:2001020 regulation of response to DNA damage stimulus; GO:1904707 positive regulation of vascular smooth muscle cell proliferation; GO:0051028 mRNA transport; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:0051236 establishment of RNA localization; GO:0045597 positive regulation of cell differentiation; GO:0051239 regulation of multicellular organismal process; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0000375 RNA splicing, via transesterification reactions; GO:0045844 positive regulation of striated muscle tissue development; GO:0051171 regulation of nitrogen compound metabolic process; GO:0061008 hepaticobiliary system development; GO:1902680 positive regulation of RNA biosynthetic process; GO:0007275 multicellular organism development; GO:0034613 cellular protein localization; GO:0008380 RNA splicing; GO:0010501 RNA secondary structure unwinding; GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development; GO:0045787 positive regulation of cell cycle; GO:0051254 positive regulation of RNA metabolic process; GO:0046794 transport of virus; GO:0048731 system development; GO:0006403 RNA localization; GO:0006405 RNA export from nucleus; GO:0060284 regulation of cell development; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:2000278 regulation of DNA biosynthetic process; GO:1901576 organic substance biosynthetic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0034248 regulation of cellular amide metabolic process; GO:0010611 regulation of cardiac muscle hypertrophy; GO:0044766 multi-organism transport; GO:0045184 establishment of protein localization; GO:0001889 liver development; GO:0043502 regulation of muscle adaptation; GO:0051247 positive regulation of protein metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0010613 positive regulation of cardiac muscle hypertrophy; GO:0048661 positive regulation of smooth muscle cell proliferation; GO:0031328 positive regulation of cellular biosynthetic process; GO:0051179 localization; GO:0000245 spliceosomal complex assembly; GO:0050793 regulation of developmental process; GO:0008284 positive regulation of cell proliferation; GO:0046620 regulation of organ growth; GO:0055021 regulation of cardiac muscle tissue growth; GO:0060420 regulation of heart growth; GO:0048634 regulation of muscle organ development; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:2000725 regulation of cardiac muscle cell differentiation; GO:0051168 nuclear export; GO:1902581 multi-organism cellular localization; GO:0044764 multi-organism cellular process; GO:0051234 establishment of localization; GO:0006353 DNA-templated transcription, termination; GO:2001141 regulation of RNA biosynthetic process; GO:0071427 mRNA-containing ribonucleoprotein complex export from nucleus; GO:0051649 establishment of localization in cell; GO:0071826 ribonucleoprotein complex subunit organization; GO:0022607 cellular component assembly; GO:0009893 positive regulation of metabolic process; GO:0050657 nucleic acid transport; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0033036 macromolecule localization; GO:0010720 positive regulation of cell development; GO:0051726 regulation of cell cycle; GO:0032502 developmental process; GO:0055024 regulation of cardiac muscle tissue development; GO:0010468 regulation of gene expression; GO:0048639 positive regulation of developmental growth; GO:0031326 regulation of cellular biosynthetic process; GO:0045727 positive regulation of translation; GO:0046784 viral mRNA export from host cell nucleus; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0046622 positive regulation of organ growth; GO:0090257 regulation of muscle system process; GO:0048636 positive regulation of muscle organ development; GO:0071166 ribonucleoprotein complex localization; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:0016202 regulation of striated muscle tissue development; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0051052 regulation of DNA metabolic process; GO:2000001 regulation of DNA damage checkpoint; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0019222 regulation of metabolic process; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0031123 RNA 3'-end processing; GO:0016043 cellular component organization; GO:1902579 multi-organism localization; GO:0051155 positive regulation of striated muscle cell differentiation; GO:1905209 positive regulation of cardiocyte differentiation; GO:0040008 regulation of growth; GO:0006725 cellular aromatic compound metabolic process; GO:0031124 mRNA 3'-end processing; GO:0060255 regulation of macromolecule metabolic process; GO:0048660 regulation of smooth muscle cell proliferation; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0019058 viral life cycle; GO:0055023 positive regulation of cardiac muscle tissue growth; GO:0048638 regulation of developmental growth; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0016032 viral process; GO:0006886 intracellular protein transport; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0006406 mRNA export from nucleus; GO:0034622 cellular macromolecular complex assembly; GO:1901976 regulation of cell cycle checkpoint; GO:0006355 regulation of transcription, DNA-templated; GO:0006369 termination of RNA polymerase II transcription; GO:1901861 regulation of muscle tissue development; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0060421 positive regulation of heart growth; GO:0043933 macromolecular complex subunit organization; GO:0051153 regulation of striated muscle cell differentiation; GO:0051641 cellular localization; GO:0070727 cellular macromolecule localization; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0071426 ribonucleoprotein complex export from nucleus; GO:0044767 single-organism developmental process; GO:0006417 regulation of translation; GO:0051246 regulation of protein metabolic process; GO:0006366 transcription from RNA polymerase II promoter; GO:0034250 positive regulation of cellular amide metabolic process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0010467 gene expression; GO:0051128 regulation of cellular component organization; GO:2000573 positive regulation of DNA biosynthetic process; GO:0071705 nitrogen compound transport; GO:1905207 regulation of cardiocyte differentiation; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005681 spliceosomal complex; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0005622 intracellular; GO:0044464 cell part; GO:0016363 nuclear matrix; GO:0000346 transcription export complex; GO:0034399 nuclear periphery; GO:1990904 ribonucleoprotein complex; GO:0043234 protein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0008026 ATP-dependent helicase activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0016887 ATPase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0042802 identical protein binding; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0004004 ATP-dependent RNA helicase activity; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017069 snRNA binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003723 RNA binding; GO:0070035 purine NTP-dependent helicase activity; GO:0005524 ATP binding; GO:0043008 ATP-dependent protein binding; GO:0004386 helicase activity; GO:0044877 macromolecular complex binding; GO:0008186 RNA-dependent ATPase activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003724 RNA helicase activity; GO:0017070 U6 snRNA binding; GO:0030621 U4 snRNA binding; GO:0042623 ATPase activity, coupled; GO:0003676 nucleic acid binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0032403 protein complex binding; GO:0036094 small molecule binding; ","K12812","UAP56; ATP-dependent RNA helicase UAP56/SUB2 [EC:3.6.4.13]","hsa03040 Spliceosome - Homo sapiens (human); hsa03015 mRNA surveillance pathway - Homo sapiens (human); hsa03013 RNA transport - Homo sapiens (human); hsa05164 Influenza A - Homo sapiens (human); ","IPR011545; IPR014014; IPR014001; IPR027417; IPR001650; ","\"DEAD/DEAH box helicase domain; RNA helicase, DEAD-box type, Q motif; Helicase superfamily 1/2, ATP-binding domain; P-loop containing nucleoside triphosphate hydrolase; Helicase, C-terminal; \"\r"]
["Q13867","Bleomycin hydrolase OS=Homo sapiens OX=9606 GN=BLMH","BLMH",52.562,61.975,37.4,18,34,18,0.873,0.91,0.887,1.061,1.137,1.134,1.248,0.000998,"cytoplasm\r","GO:0043418 homocysteine catabolic process; GO:1901606 alpha-amino acid catabolic process; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0000096 sulfur amino acid metabolic process; GO:0000209 protein polyubiquitination; GO:0071704 organic substance metabolic process; GO:0042493 response to drug; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0044248 cellular catabolic process; GO:0006508 proteolysis; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009987 cellular process; GO:0006790 sulfur compound metabolic process; GO:0016567 protein ubiquitination; GO:0044712 single-organism catabolic process; GO:0009636 response to toxic substance; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:0044282 small molecule catabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0044238 primary metabolic process; GO:1901605 alpha-amino acid metabolic process; GO:0046395 carboxylic acid catabolic process; GO:1901575 organic substance catabolic process; GO:0042221 response to chemical; GO:1901565 organonitrogen compound catabolic process; GO:0032446 protein modification by small protein conjugation; GO:0000098 sulfur amino acid catabolic process; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0016054 organic acid catabolic process; GO:0006464 cellular protein modification process; GO:0009063 cellular amino acid catabolic process; GO:0044273 sulfur compound catabolic process; GO:0050667 homocysteine metabolic process; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:0006082 organic acid metabolic process; GO:0009056 catabolic process; GO:0043436 oxoacid metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0004175 endopeptidase activity; GO:0004180 carboxypeptidase activity; GO:0008233 peptidase activity; GO:0008238 exopeptidase activity; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0005515 protein binding; GO:0004177 aminopeptidase activity; GO:0016787 hydrolase activity; GO:0008234 cysteine-type peptidase activity; GO:0004197 cysteine-type endopeptidase activity; ","K01372"]
["Q13885","Tubulin beta-2A chain OS=Homo sapiens OX=9606 GN=TUBB2A","TUBB2A",49.906,68.391,60.2,18,94,3,0.986,0.999,0.976,0.898,1.028,1.063,1.009,0.907,"cytoplasm\r","GO:0016043 cellular component organization; GO:0007010 cytoskeleton organization; GO:0007017 microtubule-based process; GO:0009987 cellular process; GO:0006996 organelle organization; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0044421 extracellular region part; GO:0005874 microtubule; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0099081 supramolecular polymer; GO:0043228 non-membrane-bounded organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005856 cytoskeleton; GO:0005634 nucleus; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0005200 structural constituent of cytoskeleton; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0003924 GTPase activity; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019001 guanyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005525 GTP binding; GO:0005198 structural molecule activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0036094 small molecule binding; ","K07375","TUBB; tubulin beta","hsa04540 Gap junction - Homo sapiens (human); hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); ","IPR003008; IPR023123; IPR008280; IPR018316; ","\"Tubulin/FtsZ, GTPase domain; Tubulin, C-terminal; Tubulin/FtsZ, C-terminal; Tubulin/FtsZ, 2-layer sandwich domain; \"\r"]
["Q13907","Isopentenyl-diphosphate Delta-isomerase 1 OS=Homo sapiens OX=9606 GN=IDI1","IDI1",26.319,17.907,21.6,5,6,5,0.93,1.069,1.008,0.927,0.911,1.101,0.977,0.749,"cytoplasm\r","GO:1901615 organic hydroxy compound metabolic process; GO:1902652 secondary alcohol metabolic process; GO:0006066 alcohol metabolic process; GO:1902653 secondary alcohol biosynthetic process; GO:0008654 phospholipid biosynthetic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044255 cellular lipid metabolic process; GO:0016125 sterol metabolic process; GO:0044237 cellular metabolic process; GO:0050993 dimethylallyl diphosphate metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0008610 lipid biosynthetic process; GO:0008299 isoprenoid biosynthetic process; GO:0016126 sterol biosynthetic process; GO:0008152 metabolic process; GO:0006695 cholesterol biosynthetic process; GO:0046490 isopentenyl diphosphate metabolic process; GO:0009987 cellular process; GO:0006629 lipid metabolic process; GO:0006720 isoprenoid metabolic process; GO:0008203 cholesterol metabolic process; GO:0044711 single-organism biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0008202 steroid metabolic process; GO:0046165 alcohol biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:1901617 organic hydroxy compound biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0090407 organophosphate biosynthetic process; GO:0006694 steroid biosynthetic process; GO:0009240 isopentenyl diphosphate biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0050992 dimethylallyl diphosphate biosynthetic process; GO:0044283 small molecule biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0006644 phospholipid metabolic process; GO:1901362 organic cyclic compound biosynthetic process; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0005777 peroxisome; GO:0042579 microbody; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0000287 magnesium ion binding; GO:0004452 isopentenyl-diphosphate delta-isomerase activity; GO:0016853 isomerase activity; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0016787 hydrolase activity; GO:0016860 intramolecular oxidoreductase activity; GO:0030145 manganese ion binding; GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds; ","K01823","idi; isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00900 Terpenoid backbone biosynthesis - Homo sapiens (human); ","IPR015797; IPR000086; ","NUDIX hydrolase domain-like; NUDIX hydrolase domain; \r"]
["Q13951","Core-binding factor subunit beta OS=Homo sapiens OX=9606 GN=CBFB","CBFB",21.508,4.4672,11.5,3,3,3,0.942,0.916,0.99,0.987,1.033,1.129,1.106,0.0944,"nucleus\r","GO:0001649 osteoblast differentiation; GO:0021700 developmental maturation; GO:0045321 leukocyte activation; GO:0097659 nucleic acid-templated transcription; GO:0048869 cellular developmental process; GO:0009891 positive regulation of biosynthetic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0048469 cell maturation; GO:0019538 protein metabolic process; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0043170 macromolecule metabolic process; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0002521 leukocyte differentiation; GO:0001503 ossification; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0002520 immune system development; GO:0070647 protein modification by small protein conjugation or removal; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006464 cellular protein modification process; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0048468 cell development; GO:0000209 protein polyubiquitination; GO:0071704 organic substance metabolic process; GO:0030098 lymphocyte differentiation; GO:0030154 cell differentiation; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0051254 positive regulation of RNA metabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0016567 protein ubiquitination; GO:0030099 myeloid cell differentiation; GO:0048731 system development; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0002376 immune system process; GO:0046649 lymphocyte activation; GO:0060216 definitive hemopoiesis; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:1901576 organic substance biosynthetic process; GO:0048534 hematopoietic or lymphoid organ development; GO:0030097 hemopoiesis; GO:0044249 cellular biosynthetic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0032446 protein modification by small protein conjugation; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044767 single-organism developmental process; GO:0031325 positive regulation of cellular metabolic process; GO:0006366 transcription from RNA polymerase II promoter; GO:0001775 cell activation; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0010467 gene expression; GO:0043412 macromolecule modification; GO:0031328 positive regulation of cellular biosynthetic process; GO:0065007 biological regulation; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003677 DNA binding; GO:0005488 binding; GO:0001071 nucleic acid binding transcription factor activity; GO:0003676 nucleic acid binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0003713 transcription coactivator activity; GO:0005515 protein binding; GO:0003712 transcription cofactor activity; GO:0000988 transcription factor activity, protein binding; GO:0003700 transcription factor activity, sequence-specific DNA binding; "]
["Q14011","Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP","CIRBP",18.648,22.592,14.5,2,5,2,0.85,1.029,1.034,0.982,1.05,0.992,1.038,0.578,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0022613 ribonucleoprotein complex biogenesis; GO:0032270 positive regulation of cellular protein metabolic process; GO:0022618 ribonucleoprotein complex assembly; GO:0043489 RNA stabilization; GO:0010608 posttranscriptional regulation of gene expression; GO:0009891 positive regulation of biosynthetic process; GO:0071826 ribonucleoprotein complex subunit organization; GO:0022607 cellular component assembly; GO:0009893 positive regulation of metabolic process; GO:0065003 macromolecular complex assembly; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0009314 response to radiation; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0045727 positive regulation of translation; GO:0080090 regulation of primary metabolic process; GO:0034249 negative regulation of cellular amide metabolic process; GO:0048522 positive regulation of cellular process; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0019222 regulation of metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0048255 mRNA stabilization; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0009628 response to abiotic stimulus; GO:0060255 regulation of macromolecule metabolic process; GO:0017148 negative regulation of translation; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0043487 regulation of RNA stability; GO:0070925 organelle assembly; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0009266 response to temperature stimulus; GO:0051171 regulation of nitrogen compound metabolic process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0009987 cellular process; GO:0034622 cellular macromolecular complex assembly; GO:0009416 response to light stimulus; GO:0006950 response to stress; GO:0010629 negative regulation of gene expression; GO:0010556 regulation of macromolecule biosynthetic process; GO:0043488 regulation of mRNA stability; GO:0048518 positive regulation of biological process; GO:0009892 negative regulation of metabolic process; GO:0034248 regulation of cellular amide metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0034063 stress granule assembly; GO:0009890 negative regulation of biosynthetic process; GO:0009411 response to UV; GO:0051247 positive regulation of protein metabolic process; GO:0009409 response to cold; GO:0006417 regulation of translation; GO:0051246 regulation of protein metabolic process; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0034250 positive regulation of cellular amide metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0010494 cytoplasmic stress granule; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005730 nucleolus; GO:0005623 cell; GO:0044422 organelle part; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0035770 ribonucleoprotein granule; GO:1990904 ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0030529 intracellular ribonucleoprotein complex; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0003723 RNA binding; GO:1901265 nucleoside phosphate binding; GO:0003730 mRNA 3'-UTR binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0045182 translation regulator activity; GO:0030371 translation repressor activity; GO:0019843 rRNA binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0003729 mRNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0070181 small ribosomal subunit rRNA binding; GO:0036094 small molecule binding; ","K13195",null,null,"IPR000504; IPR012677; IPR003954; IPR034278; ","\"RNA recognition motif domain; Nucleotide-binding alpha-beta plait domain; RNA recognition motif domain, eukaryote; RBM3/CIRBP, RNA recognition motif; \"\r"]
["Q14103","Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD","HNRNPD",38.434,120.07,33.5,14,42,13,0.955,0.991,0.969,1.018,1.061,1.012,1.06,0.0333,"nucleus\r","GO:0065008 regulation of biological quality; GO:0048732 gland development; GO:0032270 positive regulation of cellular protein metabolic process; GO:0051973 positive regulation of telomerase activity; GO:0043489 RNA stabilization; GO:0097659 nucleic acid-templated transcription; GO:0010608 posttranscriptional regulation of gene expression; GO:0007420 brain development; GO:0009891 positive regulation of biosynthetic process; GO:0032204 regulation of telomere maintenance; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0044093 positive regulation of molecular function; GO:0009719 response to endogenous stimulus; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0051347 positive regulation of transferase activity; GO:0043170 macromolecule metabolic process; GO:0007399 nervous system development; GO:0006396 RNA processing; GO:0051716 cellular response to stimulus; GO:0014070 response to organic cyclic compound; GO:0018130 heterocycle biosynthetic process; GO:0051054 positive regulation of DNA metabolic process; GO:0060359 response to ammonium ion; GO:0080090 regulation of primary metabolic process; GO:0000302 response to reactive oxygen species; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044763 single-organism cellular process; GO:0034249 negative regulation of cellular amide metabolic process; GO:0097167 circadian regulation of translation; GO:0032774 RNA biosynthetic process; GO:1904586 cellular response to putrescine; GO:0071242 cellular response to ammonium ion; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0071396 cellular response to lipid; GO:0021549 cerebellum development; GO:0019439 aromatic compound catabolic process; GO:1901575 organic substance catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0071731 response to nitric oxide; GO:0010243 response to organonitrogen compound; GO:0048513 animal organ development; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0007417 central nervous system development; GO:0071230 cellular response to amino acid stimulus; GO:2001252 positive regulation of chromosome organization; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:1901698 response to nitrogen compound; GO:0010604 positive regulation of macromolecule metabolic process; GO:0032200 telomere organization; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0016071 mRNA metabolic process; GO:0048255 mRNA stabilization; GO:1901362 organic cyclic compound biosynthetic process; GO:0071392 cellular response to estradiol stimulus; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0044707 single-multicellular organism process; GO:0006259 DNA metabolic process; GO:0009628 response to abiotic stimulus; GO:1901700 response to oxygen-containing compound; GO:0017148 negative regulation of translation; GO:0032355 response to estradiol; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0032844 regulation of homeostatic process; GO:0060249 anatomical structure homeostasis; GO:0043487 regulation of RNA stability; GO:0044270 cellular nitrogen compound catabolic process; GO:0045472 response to ether; GO:0042493 response to drug; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0009299 mRNA transcription; GO:0046483 heterocycle metabolic process; GO:0071229 cellular response to acid chemical; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0000375 RNA splicing, via transesterification reactions; GO:0051338 regulation of transferase activity; GO:0044248 cellular catabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0061008 hepaticobiliary system development; GO:1902680 positive regulation of RNA biosynthetic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0007275 multicellular organism development; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0008380 RNA splicing; GO:0030902 hindbrain development; GO:0051254 positive regulation of RNA metabolic process; GO:0006950 response to stress; GO:0042789 mRNA transcription from RNA polymerase II promoter; GO:0048731 system development; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0051602 response to electrical stimulus; GO:0071407 cellular response to organic cyclic compound; GO:0097305 response to alcohol; GO:0043696 dedifferentiation; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:2000278 regulation of DNA biosynthetic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0033044 regulation of chromosome organization; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0034248 regulation of cellular amide metabolic process; GO:1904355 positive regulation of telomere capping; GO:0009890 negative regulation of biosynthetic process; GO:0001889 liver development; GO:0051247 positive regulation of protein metabolic process; GO:0051276 chromosome organization; GO:0006996 organelle organization; GO:0051972 regulation of telomerase activity; GO:0032206 positive regulation of telomere maintenance; GO:0031325 positive regulation of cellular metabolic process; GO:0061158 3'-UTR-mediated mRNA destabilization; GO:1902074 response to salt; GO:0031328 positive regulation of cellular biosynthetic process; GO:0000723 telomere maintenance; GO:0001101 response to acid chemical; GO:0048869 cellular developmental process; GO:1904353 regulation of telomere capping; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0051130 positive regulation of cellular component organization; GO:2001141 regulation of RNA biosynthetic process; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0032846 positive regulation of homeostatic process; GO:0006979 response to oxidative stress; GO:0042752 regulation of circadian rhythm; GO:1901361 organic cyclic compound catabolic process; GO:1905661 regulation of telomerase RNA reverse transcriptase activity; GO:0060322 head development; GO:0034599 cellular response to oxidative stress; GO:0010035 response to inorganic substance; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0043200 response to amino acid; GO:0010468 regulation of gene expression; GO:0034614 cellular response to reactive oxygen species; GO:0031326 regulation of cellular biosynthetic process; GO:0045727 positive regulation of translation; GO:0043697 cell dedifferentiation; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:1904383 response to sodium phosphate; GO:0010605 negative regulation of macromolecule metabolic process; GO:0010038 response to metal ion; GO:0006401 RNA catabolic process; GO:0071732 cellular response to nitric oxide; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:0007623 circadian rhythm; GO:0071417 cellular response to organonitrogen compound; GO:1905663 positive regulation of telomerase RNA reverse transcriptase activity; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0051052 regulation of DNA metabolic process; GO:0090304 nucleic acid metabolic process; GO:0010638 positive regulation of organelle organization; GO:0006351 transcription, DNA-templated; GO:1901699 cellular response to nitrogen compound; GO:0065009 regulation of molecular function; GO:0071241 cellular response to inorganic substance; GO:0019222 regulation of metabolic process; GO:0022037 metencephalon development; GO:0048856 anatomical structure development; GO:0050779 RNA destabilization; GO:0016043 cellular component organization; GO:1901355 response to rapamycin; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0033993 response to lipid; GO:0000398 mRNA splicing, via spliceosome; GO:0051592 response to calcium ion; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0044265 cellular macromolecule catabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0033043 regulation of organelle organization; GO:0006807 nitrogen compound metabolic process; GO:1904585 response to putrescine; GO:0010556 regulation of macromolecule biosynthetic process; GO:0043488 regulation of mRNA stability; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0061157 mRNA destabilization; GO:0044249 cellular biosynthetic process; GO:0043085 positive regulation of catalytic activity; GO:1901701 cellular response to oxygen-containing compound; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:1990828 hepatocyte dedifferentiation; GO:0071495 cellular response to endogenous stimulus; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0006417 regulation of translation; GO:0048511 rhythmic process; GO:0009057 macromolecule catabolic process; GO:1902170 cellular response to reactive nitrogen species; GO:0006366 transcription from RNA polymerase II promoter; GO:0051248 negative regulation of protein metabolic process; GO:0034250 positive regulation of cellular amide metabolic process; GO:0010467 gene expression; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0051128 regulation of cellular component organization; GO:2000573 positive regulation of DNA biosynthetic process; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; GO:1901654 response to ketone; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0003723 RNA binding; GO:0003677 DNA binding; GO:0017091 AU-rich element binding; GO:1901265 nucleoside phosphate binding; GO:0003690 double-stranded DNA binding; GO:0003730 mRNA 3'-UTR binding; GO:1990837 sequence-specific double-stranded DNA binding; GO:0042162 telomeric DNA binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0003682 chromatin binding; GO:0035925 mRNA 3'-UTR AU-rich region binding; GO:0043565 sequence-specific DNA binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0003729 mRNA binding; GO:0042826 histone deacetylase binding; GO:0003680 AT DNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0008134 transcription factor binding; GO:0019899 enzyme binding; GO:0036094 small molecule binding; ","K13044",null,null,"IPR000504; IPR012677; IPR012956; ","\"RNA recognition motif domain; Nucleotide-binding alpha-beta plait domain; CARG-binding factor, N-terminal; \"\r"]
["Q14112","Nidogen-2 OS=Homo sapiens OX=9606 GN=NID2","NID2",151.25,42.693,7.1,8,11,7,1.06,1.085,1.112,0.897,0.897,0.976,0.85,0.00658,"extracellular\r","GO:0071711 basement membrane organization; GO:0022610 biological adhesion; GO:0016043 cellular component organization; GO:0031589 cell-substrate adhesion; GO:0043062 extracellular structure organization; GO:0007160 cell-matrix adhesion; GO:0044763 single-organism cellular process; GO:0007155 cell adhesion; GO:0044699 single-organism process; GO:0030198 extracellular matrix organization; GO:0009987 cellular process; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005623 cell; GO:0044420 extracellular matrix component; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0005604 basement membrane; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0031012 extracellular matrix; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0005578 proteinaceous extracellular matrix; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0005488 binding; GO:0043167 ion binding; GO:0044877 macromolecular complex binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0005518 collagen binding; GO:0005509 calcium ion binding; GO:0032403 protein complex binding; ","K06826",null,null,"IPR003886; IPR001881; IPR000742; IPR000716; IPR009030; IPR011042; IPR009017; IPR006605; IPR026823; IPR024731; IPR023413; ","\"NIDO domain; EGF-like calcium-binding domain; EGF-like domain; Thyroglobulin type-1; Growth factor receptor cysteine-rich domain; Six-bladed beta-propeller, TolB-like; Green fluorescent protein; G2 nidogen/fibulin G2F; Complement Clr-like EGF domain; EGF domain; Green fluorescent protein-like; \"\r"]
["Q14126","Desmoglein-2 OS=Homo sapiens OX=9606 GN=DSG2","DSG2",122.29,24.9,5.7,5,5,5,1.214,1.161,1.147,0.781,0.822,0.903,0.712,1.74E-3,"plasma membrane\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0086069 bundle of His cell to Purkinje myocyte communication; GO:0031424 keratinization; GO:0022414 reproductive process; GO:0048869 cellular developmental process; GO:0045216 cell-cell junction organization; GO:0044699 single-organism process; GO:0034113 heterotypic cell-cell adhesion; GO:0098901 regulation of cardiac muscle cell action potential; GO:0022610 biological adhesion; GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication; GO:0061337 cardiac conduction; GO:0009913 epidermal cell differentiation; GO:0016337 single organismal cell-cell adhesion; GO:0007507 heart development; GO:0098900 regulation of action potential; GO:0007154 cell communication; GO:0055117 regulation of cardiac muscle contraction; GO:0032879 regulation of localization; GO:0044702 single organism reproductive process; GO:0044706 multi-multicellular organism process; GO:0048545 response to steroid hormone; GO:1903115 regulation of actin filament-based movement; GO:0007155 cell adhesion; GO:0009719 response to endogenous stimulus; GO:0008544 epidermis development; GO:0044057 regulation of system process; GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules; GO:0032502 developmental process; GO:0014070 response to organic cyclic compound; GO:0060429 epithelium development; GO:0043588 skin development; GO:0098911 regulation of ventricular cardiac muscle cell action potential; GO:0030216 keratinocyte differentiation; GO:0009888 tissue development; GO:0002934 desmosome organization; GO:0060537 muscle tissue development; GO:0070268 cornification; GO:0098609 cell-cell adhesion; GO:0035637 multicellular organismal signaling; GO:0044763 single-organism cellular process; GO:0090257 regulation of muscle system process; GO:0023052 signaling; GO:0003165 Purkinje myocyte development; GO:0003164 His-Purkinje system development; GO:0032501 multicellular organismal process; GO:0006942 regulation of striated muscle contraction; GO:0051704 multi-organism process; GO:0042391 regulation of membrane potential; GO:0048513 animal organ development; GO:0003229 ventricular cardiac muscle tissue development; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0098602 single organism cell adhesion; GO:0003161 cardiac conduction system development; GO:0048856 anatomical structure development; GO:0048609 multicellular organismal reproductive process; GO:0030855 epithelial cell differentiation; GO:0014706 striated muscle tissue development; GO:0072359 circulatory system development; GO:0050794 regulation of cellular process; GO:0000003 reproduction; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0060135 maternal process involved in female pregnancy; GO:0048738 cardiac muscle tissue development; GO:0032570 response to progesterone; GO:1903522 regulation of blood circulation; GO:1901700 response to oxygen-containing compound; GO:0086042 cardiac muscle cell-cardiac muscle cell adhesion; GO:0008016 regulation of heart contraction; GO:0050896 response to stimulus; GO:0034109 homotypic cell-cell adhesion; GO:0086004 regulation of cardiac muscle cell contraction; GO:0051239 regulation of multicellular organismal process; GO:0007565 female pregnancy; GO:0033993 response to lipid; GO:0030154 cell differentiation; GO:0086091 regulation of heart rate by cardiac conduction; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0006937 regulation of muscle contraction; GO:0032970 regulation of actin filament-based process; GO:0010033 response to organic substance; GO:0032504 multicellular organism reproduction; GO:0034330 cell junction organization; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0002027 regulation of heart rate; GO:0044703 multi-organism reproductive process; GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules; GO:0012501 programmed cell death; GO:0009725 response to hormone; GO:0086065 cell communication involved in cardiac conduction; GO:1901654 response to ketone; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0016324 apical plasma membrane; GO:0044291 cell-cell contact zone; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0070161 anchoring junction; GO:0031224 intrinsic component of membrane; GO:0005911 cell-cell junction; GO:0005623 cell; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0014704 intercalated disc; GO:0016328 lateral plasma membrane; GO:0005886 plasma membrane; GO:0030057 desmosome; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0098590 plasma membrane region; GO:0001533 cornified envelope; GO:0044464 cell part; GO:0044425 membrane part; GO:1903561 extracellular vesicle; GO:0009986 cell surface; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0045177 apical part of cell; ","GO:0086080 protein binding involved in heterotypic cell-cell adhesion; GO:0050839 cell adhesion molecule binding; GO:0098631 protein binding involved in cell adhesion; GO:0005488 binding; GO:0043167 ion binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication; GO:0005515 protein binding; GO:0005509 calcium ion binding; GO:0098632 protein binding involved in cell-cell adhesion; ","K07597","DSG2; desmoglein 2","hsa05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human); ","IPR015919; IPR027397; IPR002126; ","Cadherin-like; Catenin binding domain; Cadherin; \r"]
["Q14141","Septin-6 OS=Homo sapiens OX=9606 GN=SEPT6","SEPT6",49.716,30.518,23,10,19,2,1.052,1.067,0.995,0.96,0.986,0.939,0.926,0.0409,"cytoplasm\r","GO:0032502 developmental process; GO:0000003 reproduction; GO:0048232 male gamete generation; GO:0022414 reproductive process; GO:0007283 spermatogenesis; GO:0048869 cellular developmental process; GO:0044763 single-organism cellular process; GO:0019953 sexual reproduction; GO:0044699 single-organism process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0044764 multi-organism cellular process; GO:0032501 multicellular organismal process; GO:0007276 gamete generation; GO:0051704 multi-organism process; GO:0032504 multicellular organism reproduction; GO:0030154 cell differentiation; GO:0000910 cytokinesis; GO:0016032 viral process; GO:0044767 single-organism developmental process; GO:0044703 multi-organism reproductive process; GO:0044702 single organism reproductive process; GO:0051301 cell division; GO:0022402 cell cycle process; GO:0044419 interspecies interaction between organisms; GO:0009987 cellular process; GO:0048609 multicellular organismal reproductive process; GO:0007049 cell cycle; ","GO:0099568 cytoplasmic region; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0097729 9+2 motile cilium; GO:0005623 cell; GO:0032155 cell division site part; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070382 exocytic vesicle; GO:0000793 condensed chromosome; GO:0008021 synaptic vesicle; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0044306 neuron projection terminus; GO:0097458 neuron part; GO:0000776 kinetochore; GO:0005929 cilium; GO:0042995 cell projection; GO:0044430 cytoskeletal part; GO:0000779 condensed chromosome, centromeric region; GO:0030496 midbody; GO:0032173 septin collar; GO:0030133 transport vesicle; GO:0043234 protein complex; GO:0097223 sperm part; GO:0005940 septin ring; GO:0097227 sperm annulus; GO:0005938 cell cortex; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0036126 sperm flagellum; GO:0044424 intracellular part; GO:0043679 axon terminus; GO:0000777 condensed chromosome kinetochore; GO:0044427 chromosomal part; GO:0005856 cytoskeleton; GO:0044441 ciliary part; GO:0015630 microtubule cytoskeleton; GO:0044464 cell part; GO:0098793 presynapse; GO:0005694 chromosome; GO:0032156 septin cytoskeleton; GO:0031105 septin complex; GO:0032154 cleavage furrow; GO:0044456 synapse part; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0097610 cell surface furrow; GO:0032153 cell division site; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044463 cell projection part; GO:0031514 motile cilium; GO:0005819 spindle; GO:0045202 synapse; GO:0043226 organelle; GO:0098687 chromosomal region; GO:0044448 cell cortex part; GO:0000775 chromosome, centromeric region; GO:0009986 cell surface; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0036094 small molecule binding; ","K16939","SEPT6_8_11; septin 6/8/11","hsa05100 Bacterial invasion of epithelial cells - Homo sapiens (human); ","IPR027417; IPR030379; ","P-loop containing nucleoside triphosphate hydrolase; Septin-type guanine nucleotide-binding (G) domain; \r"]
["Q14152","Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A","EIF3A",166.57,154.65,38,52,81,52,0.895,0.888,0.907,1.078,1.102,1.11,1.223,4.39e-05,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0075522 IRES-dependent viral translational initiation; GO:0022613 ribonucleoprotein complex biogenesis; GO:0075525 viral translational termination-reinitiation; GO:0006518 peptide metabolic process; GO:0022618 ribonucleoprotein complex assembly; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0031400 negative regulation of protein modification process; GO:0008152 metabolic process; GO:0010646 regulation of cell communication; GO:0044033 multi-organism metabolic process; GO:0071826 ribonucleoprotein complex subunit organization; GO:0002181 cytoplasmic translation; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0006413 translational initiation; GO:0002190 cap-independent translational initiation; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006412 translation; GO:0044419 interspecies interaction between organisms; GO:0002183 cytoplasmic translational initiation; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:0043043 peptide biosynthetic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0043603 cellular amide metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051704 multi-organism process; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:1902532 negative regulation of intracellular signal transduction; GO:0032269 negative regulation of cellular protein metabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0019081 viral translation; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0002188 translation reinitiation; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0070372 regulation of ERK1 and ERK2 cascade; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0043408 regulation of MAPK cascade; GO:0016032 viral process; GO:0042326 negative regulation of phosphorylation; GO:0019080 viral gene expression; GO:0070373 negative regulation of ERK1 and ERK2 cascade; GO:0034641 cellular nitrogen compound metabolic process; GO:0001933 negative regulation of protein phosphorylation; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0009966 regulation of signal transduction; GO:0034622 cellular macromolecular complex assembly; GO:1902531 regulation of intracellular signal transduction; GO:0002192 IRES-dependent translational initiation; GO:0001932 regulation of protein phosphorylation; GO:0006807 nitrogen compound metabolic process; GO:0048585 negative regulation of response to stimulus; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0051246 regulation of protein metabolic process; GO:0010563 negative regulation of phosphorus metabolic process; GO:0043409 negative regulation of MAPK cascade; GO:0051248 negative regulation of protein metabolic process; GO:0001732 formation of cytoplasmic translation initiation complex; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0045936 negative regulation of phosphate metabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0005874 microtubule; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m; GO:0044424 intracellular part; GO:0099512 supramolecular fiber; GO:0005623 cell; GO:0099080 supramolecular complex; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0071540 eukaryotic translation initiation factor 3 complex, eIF3e; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0099081 supramolecular polymer; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0043614 multi-eIF complex; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043234 protein complex; GO:0005852 eukaryotic translation initiation factor 3 complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003729 mRNA binding; GO:0008135 translation factor activity, RNA binding; GO:0003723 RNA binding; GO:0030971 receptor tyrosine kinase binding; GO:1990782 protein tyrosine kinase binding; GO:0005102 receptor binding; GO:0005488 binding; GO:0019901 protein kinase binding; GO:0003676 nucleic acid binding; GO:0003743 translation initiation factor activity; GO:0005515 protein binding; GO:0019900 kinase binding; GO:0005198 structural molecule activity; GO:0019899 enzyme binding; ","K03254","EIF3A; translation initiation factor 3 subunit A","hsa03013 RNA transport - Homo sapiens (human); ","IPR011991; IPR000717; ","Winged helix-turn-helix DNA-binding domain; Proteasome component (PCI) domain; \r"]
["Q14155","Rho guanine nucleotide exchange factor 7 OS=Homo sapiens OX=9606 GN=ARHGEF7","ARHGEF7",90.011,42.463,10.7,8,8,7,1.016,1.006,1.011,0.985,1.013,0.973,0.98,0.165,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0010941 regulation of cell death; GO:0030335 positive regulation of cell migration; GO:0007166 cell surface receptor signaling pathway; GO:0010762 regulation of fibroblast migration; GO:1901185 negative regulation of ERBB signaling pathway; GO:0002793 positive regulation of peptide secretion; GO:0022610 biological adhesion; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0007160 cell-matrix adhesion; GO:0034332 adherens junction organization; GO:0007155 cell adhesion; GO:0060124 positive regulation of growth hormone secretion; GO:0051099 positive regulation of binding; GO:0051056 regulation of small GTPase mediated signal transduction; GO:0030032 lamellipodium assembly; GO:0007399 nervous system development; GO:0002244 hematopoietic progenitor cell differentiation; GO:0051716 cellular response to stimulus; GO:2000394 positive regulation of lamellipodium morphogenesis; GO:0031346 positive regulation of cell projection organization; GO:1900026 positive regulation of substrate adhesion-dependent cell spreading; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0002520 immune system development; GO:0051272 positive regulation of cellular component movement; GO:0032501 multicellular organismal process; GO:0010811 positive regulation of cell-substrate adhesion; GO:0048041 focal adhesion assembly; GO:1902745 positive regulation of lamellipodium organization; GO:0048513 animal organ development; GO:0046883 regulation of hormone secretion; GO:0051336 regulation of hydrolase activity; GO:0007030 Golgi organization; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0060123 regulation of growth hormone secretion; GO:0010817 regulation of hormone levels; GO:0051094 positive regulation of developmental process; GO:2000392 regulation of lamellipodium morphogenesis; GO:0043068 positive regulation of programmed cell death; GO:0051047 positive regulation of secretion; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0043067 regulation of programmed cell death; GO:2000147 positive regulation of cell motility; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0045597 positive regulation of cell differentiation; GO:0090277 positive regulation of peptide hormone secretion; GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0051345 positive regulation of hydrolase activity; GO:2000145 regulation of cell motility; GO:1900024 regulation of substrate adhesion-dependent cell spreading; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:0090087 regulation of peptide transport; GO:1902531 regulation of intracellular signal transduction; GO:0045785 positive regulation of cell adhesion; GO:0043547 positive regulation of GTPase activity; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0060284 regulation of cell development; GO:0002376 immune system process; GO:0030334 regulation of cell migration; GO:0030155 regulation of cell adhesion; GO:0030031 cell projection assembly; GO:0006996 organelle organization; GO:0046887 positive regulation of hormone secretion; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:0010810 regulation of cell-substrate adhesion; GO:0035023 regulation of Rho protein signal transduction; GO:0050793 regulation of developmental process; GO:0097581 lamellipodium organization; GO:0010256 endomembrane system organization; GO:0009968 negative regulation of signal transduction; GO:0040017 positive regulation of locomotion; GO:0032092 positive regulation of protein binding; GO:0023051 regulation of signaling; GO:0048869 cellular developmental process; GO:0045216 cell-cell junction organization; GO:0044699 single-organism process; GO:0051046 regulation of secretion; GO:0051130 positive regulation of cellular component organization; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0007045 cell-substrate adherens junction assembly; GO:0010720 positive regulation of cell development; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0032502 developmental process; GO:0007044 cell-substrate junction assembly; GO:1904424 regulation of GTP binding; GO:0051098 regulation of binding; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:1903530 regulation of secretion by cell; GO:0010942 positive regulation of cell death; GO:0051050 positive regulation of transport; GO:0050789 regulation of biological process; GO:1903532 positive regulation of secretion by cell; GO:0030030 cell projection organization; GO:0065009 regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0034333 adherens junction assembly; GO:0048856 anatomical structure development; GO:0010763 positive regulation of fibroblast migration; GO:0034329 cell junction assembly; GO:0016043 cellular component organization; GO:0043065 positive regulation of apoptotic process; GO:0010770 positive regulation of cell morphogenesis involved in differentiation; GO:0046578 regulation of Ras protein signal transduction; GO:0031344 regulation of cell projection organization; GO:0050896 response to stimulus; GO:0043393 regulation of protein binding; GO:0002791 regulation of peptide secretion; GO:0030154 cell differentiation; GO:0048013 ephrin receptor signaling pathway; GO:1902743 regulation of lamellipodium organization; GO:1901184 regulation of ERBB signaling pathway; GO:0023056 positive regulation of signaling; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0035556 intracellular signal transduction; GO:0051049 regulation of transport; GO:0048585 negative regulation of response to stimulus; GO:0048518 positive regulation of biological process; GO:0030097 hemopoiesis; GO:0048534 hematopoietic or lymphoid organ development; GO:0043085 positive regulation of catalytic activity; GO:0034330 cell junction organization; GO:0031589 cell-substrate adhesion; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0090276 regulation of peptide hormone secretion; GO:0042058 regulation of epidermal growth factor receptor signaling pathway; GO:0051128 regulation of cellular component organization; GO:0040012 regulation of locomotion; GO:0022604 regulation of cell morphogenesis; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0005938 cell cortex; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0099568 cytoplasmic region; GO:0043025 neuronal cell body; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0000322 storage vacuole; GO:0005623 cell; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0044464 cell part; GO:0030027 lamellipodium; GO:0005912 adherens junction; GO:0043005 neuron projection; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0005924 cell-substrate adherens junction; GO:0043229 intracellular organelle; GO:0031252 cell leading edge; GO:0042995 cell projection; GO:0070161 anchoring junction; GO:0005829 cytosol; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0005773 vacuole; GO:0001726 ruffle; GO:0044297 cell body; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0005085 guanyl-nucleotide exchange factor activity; GO:0005488 binding; GO:0019901 protein kinase binding; GO:0005515 protein binding; GO:0005088 Ras guanyl-nucleotide exchange factor activity; GO:0098772 molecular function regulator; GO:0019900 kinase binding; GO:0019899 enzyme binding; GO:0005089 Rho guanyl-nucleotide exchange factor activity; ","K13710","ARHGEF7; Rho guanine nucleotide exchange factor 7","hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); ","IPR011511; IPR001452; IPR011993; IPR001715; IPR000219; IPR001849; ","Variant SH3 domain; SH3 domain; PH domain-like; Calponin homology domain; Dbl homology (DH) domain; Pleckstrin homology domain; \r"]
["Q14160","Protein scribble homolog OS=Homo sapiens OX=9606 GN=SCRIB","SCRIB",174.88,17.904,3.8,6,7,4,1.008,0.961,0.95,1.081,0.973,1.034,1.058,0.192,"nucleus\r","GO:0044700 single organism signaling; GO:0046710 GDP metabolic process; GO:0010941 regulation of cell death; GO:0048732 gland development; GO:0035148 tube formation; GO:0043009 chordate embryonic development; GO:0044237 cellular metabolic process; GO:0035315 hair cell differentiation; GO:0009913 epidermal cell differentiation; GO:0099003 vesicle-mediated transport in synapse; GO:0008152 metabolic process; GO:1901068 guanosine-containing compound metabolic process; GO:0044093 positive regulation of molecular function; GO:0008544 epidermis development; GO:0019693 ribose phosphate metabolic process; GO:0009790 embryo development; GO:0090596 sensory organ morphogenesis; GO:0048598 embryonic morphogenesis; GO:0002064 epithelial cell development; GO:0048699 generation of neurons; GO:0035239 tube morphogenesis; GO:0044763 single-organism cellular process; GO:0008347 glial cell migration; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0098877 neurotransmitter receptor transport to plasma membrane; GO:0048870 cell motility; GO:0006935 chemotaxis; GO:0051704 multi-organism process; GO:0006810 transport; GO:0043113 receptor clustering; GO:0042063 gliogenesis; GO:0007267 cell-cell signaling; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0098602 single organism cell adhesion; GO:0030855 epithelial cell differentiation; GO:0051640 organelle localization; GO:0002009 morphogenesis of an epithelium; GO:0044707 single-multicellular organism process; GO:0009259 ribonucleotide metabolic process; GO:0048519 negative regulation of biological process; GO:0036010 protein localization to endosome; GO:0009653 anatomical structure morphogenesis; GO:0021747 cochlear nucleus development; GO:0046483 heterocycle metabolic process; GO:0051345 positive regulation of hydrolase activity; GO:0006139 nucleobase-containing compound metabolic process; GO:1902580 single-organism cellular localization; GO:0016331 morphogenesis of embryonic epithelium; GO:0061245 establishment or maintenance of bipolar cell polarity; GO:0034613 cellular protein localization; GO:0090150 establishment of protein localization to membrane; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0030902 hindbrain development; GO:0060088 auditory receptor cell stereocilium organization; GO:0060562 epithelial tube morphogenesis; GO:0006950 response to stress; GO:0016079 synaptic vesicle exocytosis; GO:0008283 cell proliferation; GO:0048839 inner ear development; GO:0060117 auditory receptor cell development; GO:0006163 purine nucleotide metabolic process; GO:0097480 establishment of synaptic vesicle localization; GO:0072659 protein localization to plasma membrane; GO:0045055 regulated exocytosis; GO:0099536 synaptic signaling; GO:0031325 positive regulation of cellular metabolic process; GO:1902742 apoptotic process involved in development; GO:0019637 organophosphate metabolic process; GO:0007423 sensory organ development; GO:0007268 chemical synaptic transmission; GO:0001505 regulation of neurotransmitter levels; GO:0010256 endomembrane system organization; GO:0060113 inner ear receptor cell differentiation; GO:0072594 establishment of protein localization to organelle; GO:0051674 localization of cell; GO:0061162 establishment of monopolar cell polarity; GO:0060561 apoptotic process involved in morphogenesis; GO:0023051 regulation of signaling; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0042472 inner ear morphogenesis; GO:0051668 localization within membrane; GO:0006796 phosphate-containing compound metabolic process; GO:0009611 response to wounding; GO:0061180 mammary gland epithelium development; GO:0048729 tissue morphogenesis; GO:0045930 negative regulation of mitotic cell cycle; GO:0016337 single organismal cell-cell adhesion; GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome; GO:0009893 positive regulation of metabolic process; GO:0006915 apoptotic process; GO:0098916 anterograde trans-synaptic signaling; GO:0033036 macromolecule localization; GO:0051726 regulation of cell cycle; GO:0098609 cell-cell adhesion; GO:0023052 signaling; GO:1902582 single-organism intracellular transport; GO:0010942 positive regulation of cell death; GO:0032940 secretion by cell; GO:0065009 regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0061339 establishment or maintenance of monopolar cell polarity; GO:0016043 cellular component organization; GO:0016477 cell migration; GO:0045786 negative regulation of cell cycle; GO:1903539 protein localization to postsynaptic membrane; GO:0060255 regulation of macromolecule metabolic process; GO:0043065 positive regulation of apoptotic process; GO:0006903 vesicle targeting; GO:0021548 pons development; GO:0000904 cell morphogenesis involved in differentiation; GO:0071704 organic substance metabolic process; GO:1903540 establishment of protein localization to postsynaptic membrane; GO:0072175 epithelial tube formation; GO:0090630 activation of GTPase activity; GO:0030154 cell differentiation; GO:0072583 clathrin-dependent endocytosis; GO:0023056 positive regulation of signaling; GO:0016032 viral process; GO:0030010 establishment of cell polarity; GO:0043615 astrocyte cell migration; GO:1902946 protein localization to early endosome; GO:0099537 trans-synaptic signaling; GO:0034641 cellular nitrogen compound metabolic process; GO:0001919 regulation of receptor recycling; GO:0016080 synaptic vesicle targeting; GO:0017156 calcium ion regulated exocytosis; GO:0042490 mechanoreceptor differentiation; GO:0009792 embryo development ending in birth or egg hatching; GO:0044802 single-organism membrane organization; GO:0043085 positive regulation of catalytic activity; GO:0014020 primary neural tube formation; GO:0046128 purine ribonucleoside metabolic process; GO:0008219 cell death; GO:0042471 ear morphogenesis; GO:0099639 neurotransmitter receptor transport, endosome to plasma membrane; GO:1902414 protein localization to cell junction; GO:0060119 inner ear receptor cell development; GO:0006836 neurotransmitter transport; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0060563 neuroepithelial cell differentiation; GO:0009116 nucleoside metabolic process; GO:0065008 regulation of biological quality; GO:0071896 protein localization to adherens junction; GO:0007420 brain development; GO:0035088 establishment or maintenance of apical/basal cell polarity; GO:0007269 neurotransmitter secretion; GO:0032989 cellular component morphogenesis; GO:0090002 establishment of protein localization to plasma membrane; GO:0009185 ribonucleoside diphosphate metabolic process; GO:0015031 protein transport; GO:0048857 neural nucleus development; GO:0022610 biological adhesion; GO:0009605 response to external stimulus; GO:0048562 embryonic organ morphogenesis; GO:0007155 cell adhesion; GO:0033365 protein localization to organelle; GO:0008104 protein localization; GO:0044419 interspecies interaction between organisms; GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0007399 nervous system development; GO:0009179 purine ribonucleoside diphosphate metabolic process; GO:0048489 synaptic vesicle transport; GO:0072657 protein localization to membrane; GO:0044281 small molecule metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0007009 plasma membrane organization; GO:0007163 establishment or maintenance of cell polarity; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0000902 cell morphogenesis; GO:0048513 animal organ development; GO:0043583 ear development; GO:0051336 regulation of hydrolase activity; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0007417 central nervous system development; GO:0010604 positive regulation of macromolecule metabolic process; GO:0009887 animal organ morphogenesis; GO:0042330 taxis; GO:0060603 mammary gland duct morphogenesis; GO:0009126 purine nucleoside monophosphate metabolic process; GO:0043068 positive regulation of programmed cell death; GO:0099643 signal release from synapse; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0007346 regulation of mitotic cell cycle; GO:0043067 regulation of programmed cell death; GO:0048523 negative regulation of cellular process; GO:1990778 protein localization to cell periphery; GO:0030879 mammary gland development; GO:0099637 neurotransmitter receptor transport; GO:0060606 tube closure; GO:1902578 single-organism localization; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:1901135 carbohydrate derivative metabolic process; GO:0042491 auditory receptor cell differentiation; GO:0060443 mammary gland morphogenesis; GO:0006898 receptor-mediated endocytosis; GO:0007275 multicellular organism development; GO:0035089 establishment of apical/basal cell polarity; GO:0009119 ribonucleoside metabolic process; GO:0001843 neural tube closure; GO:0036465 synaptic vesicle recycling; GO:0043547 positive regulation of GTPase activity; GO:0048731 system development; GO:0099638 endosome to plasma membrane protein transport; GO:0016192 vesicle-mediated transport; GO:0071702 organic substance transport; GO:0023061 signal release; GO:0044238 primary metabolic process; GO:0051656 establishment of organelle localization; GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane; GO:0045184 establishment of protein localization; GO:0030182 neuron differentiation; GO:0006793 phosphorus metabolic process; GO:0098969 neurotransmitter receptor transport to postsynaptic membrane; GO:0097479 synaptic vesicle localization; GO:0061024 membrane organization; GO:0006928 movement of cell or subcellular component; GO:0012501 programmed cell death; GO:0051179 localization; GO:1901564 organonitrogen compound metabolic process; GO:0006887 exocytosis; GO:0009123 nucleoside monophosphate metabolic process; GO:0001841 neural tube formation; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0022008 neurogenesis; GO:0044764 multi-organism cellular process; GO:0009135 purine nucleoside diphosphate metabolic process; GO:0099504 synaptic vesicle cycle; GO:0051234 establishment of localization; GO:0008105 asymmetric protein localization; GO:0097120 receptor localization to synapse; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0006753 nucleoside phosphate metabolic process; GO:0060322 head development; GO:1990126 retrograde transport, endosome to plasma membrane; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0035295 tube development; GO:0051650 establishment of vesicle localization; GO:0046037 GMP metabolic process; GO:0009888 tissue development; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0016197 endosomal transport; GO:0001921 positive regulation of receptor recycling; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0030030 cell projection organization; GO:0002065 columnar/cuboidal epithelial cell differentiation; GO:0060122 inner ear receptor stereocilium organization; GO:0019222 regulation of metabolic process; GO:0022037 metencephalon development; GO:0040011 locomotion; GO:1901657 glycosyl compound metabolic process; GO:0048856 anatomical structure development; GO:0035418 protein localization to synapse; GO:0006725 cellular aromatic compound metabolic process; GO:0048568 embryonic organ development; GO:0099531 presynaptic process involved in chemical synaptic transmission; GO:0021915 neural tube development; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0051648 vesicle localization; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0009132 nucleoside diphosphate metabolic process; GO:0050918 positive chemotaxis; GO:0098876 vesicle-mediated transport to the plasma membrane; GO:0006807 nitrogen compound metabolic process; GO:0002066 columnar/cuboidal epithelial cell development; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0002093 auditory receptor cell morphogenesis; GO:0051641 cellular localization; GO:0001838 embryonic epithelial tube formation; GO:0048488 synaptic vesicle endocytosis; GO:0070727 cellular macromolecule localization; GO:0042060 wound healing; GO:0044767 single-organism developmental process; GO:0009150 purine ribonucleotide metabolic process; GO:0022612 gland morphogenesis; GO:0065007 biological regulation; ","GO:0016323 basolateral plasma membrane; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0044291 cell-cell contact zone; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0035748 myelin sheath abaxonal region; GO:0044424 intracellular part; GO:0005913 cell-cell adherens junction; GO:0005911 cell-cell junction; GO:0005623 cell; GO:0032279 asymmetric synapse; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0098590 plasma membrane region; GO:0098793 presynapse; GO:0043209 myelin sheath; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0014069 postsynaptic density; GO:0030027 lamellipodium; GO:1903561 extracellular vesicle; GO:0005912 adherens junction; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0034750 Scrib-APC-beta-catenin complex; GO:0098984 neuron to neuron synapse; GO:0044456 synapse part; GO:0043233 organelle lumen; GO:0031252 cell leading edge; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0031981 nuclear lumen; GO:0005576 extracellular region; GO:0045202 synapse; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0098794 postsynapse; GO:0044459 plasma membrane part; GO:0043234 protein complex; GO:0099572 postsynaptic specialization; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0035254 glutamate receptor binding; GO:0050839 cell adhesion molecule binding; GO:0016301 kinase activity; GO:0003824 catalytic activity; GO:0005102 receptor binding; GO:0004385 guanylate kinase activity; GO:0005488 binding; GO:0019205 nucleobase-containing compound kinase activity; GO:0045296 cadherin binding; GO:0005515 protein binding; GO:0035255 ionotropic glutamate receptor binding; GO:0016776 phosphotransferase activity, phosphate group as acceptor; GO:0016740 transferase activity; GO:0019201 nucleotide kinase activity; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K16175","SCRIB; protein scribble","hsa04390 Hippo signaling pathway - Homo sapiens (human); hsa04530 Tight junction - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa05203 Viral carcinogenesis - Homo sapiens (human); ","IPR001478; IPR032675; ","\"PDZ domain; Leucine-rich repeat domain, L domain-like; \"\r"]
["Q14166","Tubulin--tyrosine ligase-like protein 12 OS=Homo sapiens OX=9606 GN=TTLL12","TTLL12",74.403,77.239,19.9,10,17,10,1.05,0.952,0.996,1.007,1.011,1.001,1.007,0.81,"cytoplasm\r","GO:0008152 metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0044267 cellular protein metabolic process; GO:0006464 cellular protein modification process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0044238 primary metabolic process; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:0044237 cellular metabolic process; GO:0009987 cellular process; GO:0071704 organic substance metabolic process; ",null,"GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K16609"]
["Q14195","Dihydropyrimidinase-related protein 3 OS=Homo sapiens OX=9606 GN=DPYSL3","DPYSL3",61.963,186.5,40.9,16,39,13,1.113,1.134,1.135,0.884,0.875,0.889,0.783,3.23E-6,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0051093 negative regulation of developmental process; GO:0045666 positive regulation of neuron differentiation; GO:0060491 regulation of cell projection assembly; GO:0051129 negative regulation of cellular component organization; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0051241 negative regulation of multicellular organismal process; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0071345 cellular response to cytokine stimulus; GO:0040013 negative regulation of locomotion; GO:0009611 response to wounding; GO:0051130 positive regulation of cellular component organization; GO:0030036 actin cytoskeleton organization; GO:0051240 positive regulation of multicellular organismal process; GO:0022607 cellular component assembly; GO:0032879 regulation of localization; GO:0065003 macromolecular complex assembly; GO:0010720 positive regulation of cell development; GO:0045596 negative regulation of cell differentiation; GO:0070887 cellular response to chemical stimulus; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0071822 protein complex subunit organization; GO:0034097 response to cytokine; GO:0031346 positive regulation of cell projection organization; GO:0048699 generation of neurons; GO:0051962 positive regulation of nervous system development; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:2000146 negative regulation of cell motility; GO:0032501 multicellular organismal process; GO:0050768 negative regulation of neurogenesis; GO:1902589 single-organism organelle organization; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0045664 regulation of neuron differentiation; GO:0045665 negative regulation of neuron differentiation; GO:0010721 negative regulation of cell development; GO:0070271 protein complex biogenesis; GO:0051094 positive regulation of developmental process; GO:0048856 anatomical structure development; GO:0097435 supramolecular fiber organization; GO:0010975 regulation of neuron projection development; GO:0051271 negative regulation of cellular component movement; GO:2000026 regulation of multicellular organismal development; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0051260 protein homooligomerization; GO:0071310 cellular response to organic substance; GO:0007015 actin filament organization; GO:0044087 regulation of cellular component biogenesis; GO:0031344 regulation of cell projection organization; GO:0051017 actin filament bundle assembly; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0045597 positive regulation of cell differentiation; GO:0048468 cell development; GO:0051239 regulation of multicellular organismal process; GO:0051489 regulation of filopodium assembly; GO:0051259 protein oligomerization; GO:0030154 cell differentiation; GO:0051961 negative regulation of nervous system development; GO:2000145 regulation of cell motility; GO:0031345 negative regulation of cell projection organization; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0045595 regulation of cell differentiation; GO:0051764 actin crosslink formation; GO:0006950 response to stress; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0051960 regulation of nervous system development; GO:0060284 regulation of cell development; GO:0030334 regulation of cell migration; GO:0010977 negative regulation of neuron projection development; GO:0010033 response to organic substance; GO:0048518 positive regulation of biological process; GO:0061572 actin filament bundle organization; GO:0043933 macromolecular complex subunit organization; GO:0030182 neuron differentiation; GO:0051491 positive regulation of filopodium assembly; GO:0048678 response to axon injury; GO:0030336 negative regulation of cell migration; GO:0010976 positive regulation of neuron projection development; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0030029 actin filament-based process; GO:0050769 positive regulation of neurogenesis; GO:0051128 regulation of cellular component organization; GO:0040012 regulation of locomotion; GO:0050793 regulation of developmental process; GO:0044089 positive regulation of cellular component biogenesis; GO:0050767 regulation of neurogenesis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0030426 growth cone; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070382 exocytic vesicle; GO:0044464 cell part; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0030027 lamellipodium; GO:0043005 neuron projection; GO:0005884 actin filament; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0031941 filamentous actin; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0031252 cell leading edge; GO:0042995 cell projection; GO:0099513 polymeric cytoskeletal fiber; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0030427 site of polarized growth; GO:0044463 cell projection part; GO:0005829 cytosol; GO:0015629 actin cytoskeleton; GO:0005576 extracellular region; GO:0099081 supramolecular polymer; GO:0043226 organelle; GO:0044297 cell body; GO:0043234 protein complex; GO:0030133 transport vesicle; GO:0044444 cytoplasmic part; ","GO:0035374 chondroitin sulfate binding; GO:0097367 carbohydrate derivative binding; GO:0008092 cytoskeletal protein binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0019904 protein domain specific binding; GO:0016787 hydrolase activity; GO:0043168 anion binding; GO:0005515 protein binding; GO:0005539 glycosaminoglycan binding; GO:0031005 filamin binding; GO:0017124 SH3 domain binding; GO:1901681 sulfur compound binding; GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; ",{"$nulls":3},"IPR032466; IPR006680; IPR011059; ","\"Metal-dependent hydrolase; Amidohydrolase-related; Metal-dependent hydrolase, composite domain; \"\r"]
["Q14204","Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1","DYNC1H1",532.4,323.31,31,135,219,135,1.001,1.013,1.001,0.998,0.998,0.993,0.991,0.115,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0045321 leukocyte activation; GO:0022618 ribonucleoprotein complex assembly; GO:0007067 mitotic nuclear division; GO:0060271 cilium assembly; GO:0044699 single-organism process; GO:0044782 cilium organization; GO:0051234 establishment of localization; GO:0051649 establishment of localization in cell; GO:0071826 ribonucleoprotein complex subunit organization; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0044770 cell cycle phase transition; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0000278 mitotic cell cycle; GO:0002443 leukocyte mediated immunity; GO:0048002 antigen processing and presentation of peptide antigen; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0002495 antigen processing and presentation of peptide antigen via MHC class II; GO:0002444 myeloid leukocyte mediated immunity; GO:0006810 transport; GO:0019884 antigen processing and presentation of exogenous antigen; GO:1902589 single-organism organelle organization; GO:0000226 microtubule cytoskeleton organization; GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; GO:0030030 cell projection organization; GO:0032940 secretion by cell; GO:1902850 microtubule cytoskeleton organization involved in mitosis; GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II; GO:0043299 leukocyte degranulation; GO:0000086 G2/M transition of mitotic cell cycle; GO:0051640 organelle localization; GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0048285 organelle fission; GO:0051653 spindle localization; GO:0048193 Golgi vesicle transport; GO:0007051 spindle organization; GO:0097711 ciliary basal body docking; GO:0050896 response to stimulus; GO:0022406 membrane docking; GO:1903047 mitotic cell cycle process; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0070925 organelle assembly; GO:0036230 granulocyte activation; GO:0033962 cytoplasmic mRNA processing body assembly; GO:0007010 cytoskeleton organization; GO:0007052 mitotic spindle organization; GO:0009987 cellular process; GO:0044772 mitotic cell cycle phase transition; GO:0051293 establishment of spindle localization; GO:0034622 cellular macromolecular complex assembly; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0051656 establishment of organelle localization; GO:0043312 neutrophil degranulation; GO:0007017 microtubule-based process; GO:0002263 cell activation involved in immune response; GO:0030031 cell projection assembly; GO:0043933 macromolecular complex subunit organization; GO:0051641 cellular localization; GO:0002366 leukocyte activation involved in immune response; GO:0019882 antigen processing and presentation; GO:0034063 stress granule assembly; GO:0007018 microtubule-based movement; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:0006996 organelle organization; GO:0006928 movement of cell or subcellular component; GO:0001775 cell activation; GO:0000280 nuclear division; GO:0044839 cell cycle G2/M phase transition; GO:0022402 cell cycle process; GO:0006955 immune response; GO:0051179 localization; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0007049 cell cycle; GO:0006887 exocytosis; GO:0071840 cellular component organization or biogenesis; ","GO:0034774 secretory granule lumen; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005874 microtubule; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0099512 supramolecular fiber; GO:0035578 azurophil granule lumen; GO:0098858 actin-based cell projection; GO:0005623 cell; GO:0099080 supramolecular complex; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0005815 microtubule organizing center; GO:1902494 catalytic complex; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0030175 filopodium; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0099513 polymeric cytoskeletal fiber; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005875 microtubule associated complex; GO:0030286 dynein complex; GO:0005868 cytoplasmic dynein complex; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0099081 supramolecular polymer; GO:0042582 azurophil granule; GO:0031012 extracellular matrix; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0005813 centrosome; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0003774 motor activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0016887 ATPase activity; GO:0051959 dynein light intermediate chain binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0003777 microtubule motor activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003723 RNA binding; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003676 nucleic acid binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; ","K10413","DYNC1H; dynein heavy chain 1, cytosolic","hsa05132 Salmonella infection - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); hsa04962 Vasopressin-regulated water reabsorption - Homo sapiens (human); ","IPR004273; IPR011704; IPR013602; IPR027417; IPR013594; IPR024317; IPR003593; IPR024743; ","\"Dynein heavy chain domain; ATPase, dynein-related, AAA domain; Dynein heavy chain, domain-2; P-loop containing nucleoside triphosphate hydrolase; Dynein heavy chain, domain-1; Dynein heavy chain, P-loop containing D4 domain; AAA+ ATPase domain; Dynein heavy chain, coiled coil stalk; \"\r"]
["Q14240","Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2","EIF4A2",46.402,20.381,37.3,18,37,6,1.165,1.202,1.234,0.793,0.845,0.8,0.677,1.17E-4,"nucleus\r","GO:0006518 peptide metabolic process; GO:0010608 posttranscriptional regulation of gene expression; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0051253 negative regulation of RNA metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0006413 translational initiation; GO:1901361 organic cyclic compound catabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0006412 translation; GO:0044419 interspecies interaction between organisms; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0043043 peptide biosynthetic process; GO:1900260 negative regulation of RNA-directed 5'-3' RNA polymerase activity; GO:1901360 organic cyclic compound metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0043603 cellular amide metabolic process; GO:0051348 negative regulation of transferase activity; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051704 multi-organism process; GO:0016070 RNA metabolic process; GO:0006401 RNA catabolic process; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; GO:0050790 regulation of catalytic activity; GO:0006402 mRNA catabolic process; GO:1902679 negative regulation of RNA biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0016071 mRNA metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044267 cellular protein metabolic process; GO:1900259 regulation of RNA-directed 5'-3' RNA polymerase activity; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0016032 viral process; GO:0009889 regulation of biosynthetic process; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0009059 macromolecule biosynthetic process; GO:0010501 RNA secondary structure unwinding; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0034248 regulation of cellular amide metabolic process; GO:0009890 negative regulation of biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0051246 regulation of protein metabolic process; GO:0006417 regulation of translation; GO:0009057 macromolecule catabolic process; GO:0006446 regulation of translational initiation; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0009056 catabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0048471 perinuclear region of cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0043234 protein complex; GO:0005829 cytosol; GO:0005623 cell; GO:0044444 cytoplasmic part; GO:0016281 eukaryotic translation initiation factor 4F complex; ","GO:1901265 nucleoside phosphate binding; GO:0008026 ATP-dependent helicase activity; GO:0003743 translation initiation factor activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0016887 ATPase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0004004 ATP-dependent RNA helicase activity; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003723 RNA binding; GO:0070035 purine NTP-dependent helicase activity; GO:0005524 ATP binding; GO:0004386 helicase activity; GO:0008186 RNA-dependent ATPase activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0008135 translation factor activity, RNA binding; GO:0097367 carbohydrate derivative binding; GO:0003724 RNA helicase activity; GO:0042623 ATPase activity, coupled; GO:0003676 nucleic acid binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; ","K03257","EIF4A; translation initiation factor 4A","hsa03013 RNA transport - Homo sapiens (human); ","IPR014014; IPR011545; IPR014001; IPR027417; IPR001650; ","\"RNA helicase, DEAD-box type, Q motif; DEAD/DEAH box helicase domain; Helicase superfamily 1/2, ATP-binding domain; P-loop containing nucleoside triphosphate hydrolase; Helicase, C-terminal; \"\r"]
["Q14254","Flotillin-2 OS=Homo sapiens OX=9606 GN=FLOT2","FLOT2",47.064,33.569,22.7,9,11,9,1,1.015,0.94,1.015,1.01,1.048,1.04,0.205,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0050863 regulation of T cell activation; GO:0002694 regulation of leukocyte activation; GO:0065008 regulation of biological quality; GO:0010256 endomembrane system organization; GO:1903903 regulation of establishment of T cell polarity; GO:0044699 single-organism process; GO:0090002 establishment of protein localization to plasma membrane; GO:0051249 regulation of lymphocyte activation; GO:0051234 establishment of localization; GO:0022610 biological adhesion; GO:0022607 cellular component assembly; GO:0045661 regulation of myoblast differentiation; GO:0008544 epidermis development; GO:0007155 cell adhesion; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0051147 regulation of muscle cell differentiation; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0032878 regulation of establishment or maintenance of cell polarity; GO:0009888 tissue development; GO:1903905 positive regulation of establishment of T cell polarity; GO:0072657 protein localization to membrane; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0051251 positive regulation of lymphocyte activation; GO:0007009 plasma membrane organization; GO:0010605 negative regulation of macromolecule metabolic process; GO:0050865 regulation of cell activation; GO:0050789 regulation of biological process; GO:0044860 protein localization to plasma membrane raft; GO:2000114 regulation of establishment of cell polarity; GO:0019222 regulation of metabolic process; GO:0002682 regulation of immune system process; GO:0048856 anatomical structure development; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0060255 regulation of macromolecule metabolic process; GO:1902992 negative regulation of amyloid precursor protein catabolic process; GO:1903044 protein localization to membrane raft; GO:0048519 negative regulation of biological process; GO:1990778 protein localization to cell periphery; GO:0050867 positive regulation of cell activation; GO:1902578 single-organism localization; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:1902580 single-organism cellular localization; GO:0031579 membrane raft organization; GO:1902991 regulation of amyloid precursor protein catabolic process; GO:0034613 cellular protein localization; GO:0090150 establishment of protein localization to membrane; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0045785 positive regulation of cell adhesion; GO:0010629 negative regulation of gene expression; GO:0022409 positive regulation of cell-cell adhesion; GO:0071709 membrane assembly; GO:0044802 single-organism membrane organization; GO:0001765 membrane raft assembly; GO:0044091 membrane biogenesis; GO:0009892 negative regulation of metabolic process; GO:1903039 positive regulation of leukocyte cell-cell adhesion; GO:0048518 positive regulation of biological process; GO:0022407 regulation of cell-cell adhesion; GO:0030155 regulation of cell adhesion; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0002696 positive regulation of leukocyte activation; GO:0072659 protein localization to plasma membrane; GO:0070727 cellular macromolecule localization; GO:0050870 positive regulation of T cell activation; GO:0051246 regulation of protein metabolic process; GO:0002684 positive regulation of immune system process; GO:0061024 membrane organization; GO:0051248 negative regulation of protein metabolic process; GO:0031647 regulation of protein stability; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0050821 protein stabilization; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0098857 membrane microdomain; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0005913 cell-cell adherens junction; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0098590 plasma membrane region; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0098589 membrane region; GO:0030027 lamellipodium; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0016600 flotillin complex; GO:0005924 cell-substrate adherens junction; GO:0031252 cell leading edge; GO:0042995 cell projection; GO:0098797 plasma membrane protein complex; GO:0070161 anchoring junction; GO:0012506 vesicle membrane; GO:0005901 caveola; GO:0005576 extracellular region; GO:0002080 acrosomal membrane; GO:0005886 plasma membrane; GO:0030667 secretory granule membrane; GO:0097223 sperm part; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0016323 basolateral plasma membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0044291 cell-cell contact zone; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005911 cell-cell junction; GO:0044425 membrane part; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0005768 endosome; GO:0030141 secretory granule; GO:0045121 membrane raft; GO:0030139 endocytic vesicle; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0001931 uropod; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0031254 cell trailing edge; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0044853 plasma membrane raft; GO:0001669 acrosomal vesicle; GO:0044444 cytoplasmic part; ","GO:0002020 protease binding; GO:0035254 glutamate receptor binding; GO:0046982 protein heterodimerization activity; GO:0005102 receptor binding; GO:0005488 binding; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:0035255 ionotropic glutamate receptor binding; GO:0019899 enzyme binding; ","K07192","FLOT; flotillin","hsa04910 Insulin signaling pathway - Homo sapiens (human); ","IPR031905; IPR001107; ","\"Flotillin, C-terminal domain; Band 7 domain; \"\r"]
["Q14258","E3 ubiquitin/ISG15 ligase TRIM25 OS=Homo sapiens OX=9606 GN=TRIM25","TRIM25",70.973,89.87,23.5,11,15,11,0.986,0.847,1.013,1.111,1.021,1.036,1.113,0.149,"nucleus\r","GO:0044700 single organism signaling; GO:0007166 cell surface receptor signaling pathway; GO:0098542 defense response to other organism; GO:0036503 ERAD pathway; GO:0071345 cellular response to cytokine stimulus; GO:0044237 cellular metabolic process; GO:0009607 response to biotic stimulus; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling; GO:0044093 positive regulation of molecular function; GO:0019985 translesion synthesis; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0046597 negative regulation of viral entry into host cell; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0031323 regulation of cellular metabolic process; GO:0051704 multi-organism process; GO:1903506 regulation of nucleic acid-templated transcription; GO:1901575 organic substance catabolic process; GO:0051092 positive regulation of NF-kappaB transcription factor activity; GO:0051090 regulation of sequence-specific DNA binding transcription factor activity; GO:0044710 single-organism metabolic process; GO:0030163 protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0034976 response to endoplasmic reticulum stress; GO:0006259 DNA metabolic process; GO:0044267 cellular protein metabolic process; GO:1901700 response to oxygen-containing compound; GO:0000731 DNA synthesis involved in DNA repair; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0051239 regulation of multicellular organismal process; GO:1903901 negative regulation of viral life cycle; GO:0006301 postreplication repair; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0044248 cellular catabolic process; GO:0009966 regulation of signal transduction; GO:1902531 regulation of intracellular signal transduction; GO:0016567 protein ubiquitination; GO:0006950 response to stress; GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0043900 regulation of multi-organism process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0007584 response to nutrient; GO:1901576 organic substance biosynthetic process; GO:0006974 cellular response to DNA damage stimulus; GO:1902186 regulation of viral release from host cell; GO:0032446 protein modification by small protein conjugation; GO:0048584 positive regulation of response to stimulus; GO:0043412 macromolecule modification; GO:0006955 immune response; GO:0070646 protein modification by small protein removal; GO:0043627 response to estrogen; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0071346 cellular response to interferon-gamma; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0001818 negative regulation of cytokine production; GO:0040013 negative regulation of locomotion; GO:0060333 interferon-gamma-mediated signaling pathway; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0046596 regulation of viral entry into host cell; GO:0070887 cellular response to chemical stimulus; GO:0033273 response to vitamin; GO:0048525 negative regulation of viral process; GO:0010468 regulation of gene expression; GO:0034097 response to cytokine; GO:0031326 regulation of cellular biosynthetic process; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity; GO:0070647 protein modification by small protein conjugation or removal; GO:0023052 signaling; GO:0006513 protein monoubiquitination; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0051607 defense response to virus; GO:0090304 nucleic acid metabolic process; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0006952 defense response; GO:0036211 protein modification process; GO:0009615 response to virus; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0032479 regulation of type I interferon production; GO:0044257 cellular protein catabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0043207 response to external biotic stimulus; GO:0016579 protein deubiquitination; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0045087 innate immune response; GO:0071704 organic substance metabolic process; GO:0009991 response to extracellular stimulus; GO:0033993 response to lipid; GO:0023056 positive regulation of signaling; GO:0033280 response to vitamin D; GO:0016032 viral process; GO:0006508 proteolysis; GO:0071897 DNA biosynthetic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0010647 positive regulation of cell communication; GO:0009059 macromolecule biosynthetic process; GO:0019221 cytokine-mediated signaling pathway; GO:0009987 cellular process; GO:0043632 modification-dependent macromolecule catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0019941 modification-dependent protein catabolic process; GO:0044712 single-organism catabolic process; GO:0050792 regulation of viral process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0034341 response to interferon-gamma; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0043901 negative regulation of multi-organism process; GO:0006281 DNA repair; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:1902187 negative regulation of viral release from host cell; GO:0009057 macromolecule catabolic process; GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling; GO:0001817 regulation of cytokine production; GO:0009967 positive regulation of signal transduction; GO:0031667 response to nutrient levels; GO:0040012 regulation of locomotion; GO:1903900 regulation of viral life cycle; GO:0032480 negative regulation of type I interferon production; GO:0009056 catabolic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0003723 RNA binding; GO:0019787 ubiquitin-like protein transferase activity; GO:0043167 ion binding; GO:0016874 ligase activity; GO:0005515 protein binding; GO:0061659 ubiquitin-like protein ligase activity; GO:0008270 zinc ion binding; GO:0003700 transcription factor activity, sequence-specific DNA binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0061630 ubiquitin protein ligase activity; GO:0050839 cell adhesion molecule binding; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway; GO:0003676 nucleic acid binding; GO:0001071 nucleic acid binding transcription factor activity; GO:0004842 ubiquitin-protein transferase activity; GO:0045296 cadherin binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0016740 transferase activity; ","K10652","TRIM25; tripartite motif-containing protein 25 [EC:2.3.2.27]","hsa04622 RIG-I-like receptor signaling pathway - Homo sapiens (human); hsa04064 NF-kappa B signaling pathway - Homo sapiens (human); hsa05164 Influenza A - Homo sapiens (human); ","IPR006574; IPR001841; IPR001870; IPR013320; IPR000315; IPR003877; IPR027370; IPR013083; IPR003879; ","\"SPRY-associated; Zinc finger, RING-type; B30.2/SPRY domain; Concanavalin A-like lectin/glucanase domain; B-box-type zinc finger; SPRY domain; RING-type zinc-finger, LisH dimerisation motif; Zinc finger, RING/FYVE/PHD-type; Butyrophylin-like; \"\r"]
["Q14314","Fibroleukin OS=Homo sapiens OX=9606 GN=FGL2","FGL2",50.228,8.0917,9.3,5,6,5,1.116,1.227,1.138,0.936,0.848,0.769,0.733,0.008,"extracellular\r","GO:0045321 leukocyte activation; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0051234 establishment of localization; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0006508 proteolysis; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0002443 leukocyte mediated immunity; GO:0016192 vesicle-mediated transport; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:0043312 neutrophil degranulation; GO:0002263 cell activation involved in immune response; GO:0002444 myeloid leukocyte mediated immunity; GO:0002366 leukocyte activation involved in immune response; GO:0006810 transport; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0032940 secretion by cell; GO:0001775 cell activation; GO:0043299 leukocyte degranulation; GO:0051179 localization; GO:0006955 immune response; GO:0006887 exocytosis; ","GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0101002 ficolin-1-rich granule; GO:0070062 extracellular exosome; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0005577 fibrinogen complex; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0008233 peptidase activity; GO:0016787 hydrolase activity; GO:0003824 catalytic activity; ",{"$nulls":3},"IPR002181; IPR014716; IPR014715; ","\"Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain; Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1; Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2; \"\r"]
["Q14376","UDP-glucose 4-epimerase OS=Homo sapiens OX=9606 GN=GALE","GALE",38.281,6.8053,6.9,2,2,2,1.006,0.833,0.856,1.188,1.019,1.098,1.226,0.0493,"cytoplasm\r","GO:0046365 monosaccharide catabolic process; GO:0044724 single-organism carbohydrate catabolic process; GO:0044712 single-organism catabolic process; GO:0044281 small molecule metabolic process; GO:0044699 single-organism process; GO:0044282 small molecule catabolic process; GO:0005975 carbohydrate metabolic process; GO:0044238 primary metabolic process; GO:0071704 organic substance metabolic process; GO:0016052 carbohydrate catabolic process; GO:1901575 organic substance catabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0008152 metabolic process; GO:0044710 single-organism metabolic process; GO:0005996 monosaccharide metabolic process; GO:0019388 galactose catabolic process; GO:0019320 hexose catabolic process; GO:0009056 catabolic process; GO:0006012 galactose metabolic process; GO:0019318 hexose metabolic process; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016853 isomerase activity; GO:0042802 identical protein binding; GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity; GO:0016854 racemase and epimerase activity; GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives; GO:0003824 catalytic activity; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:0003978 UDP-glucose 4-epimerase activity; ","K01784","galE; UDP-glucose 4-epimerase [EC:5.1.3.2]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00052 Galactose metabolism - Homo sapiens (human); hsa00520 Amino sugar and nucleotide sugar metabolism - Homo sapiens (human); ","IPR016040; ","NAD(P)-binding domain; \r"]
["Q14444","Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1","CAPRIN1",78.365,29.042,10,7,8,7,0.91,0.924,0.877,1.086,1.076,1.11,1.207,0.000478,"nucleus\r","GO:0045666 positive regulation of neuron differentiation; GO:0010608 posttranscriptional regulation of gene expression; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0051130 positive regulation of cellular component organization; GO:0051240 positive regulation of multicellular organismal process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0010720 positive regulation of cell development; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0060998 regulation of dendritic spine development; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0031346 positive regulation of cell projection organization; GO:0048699 generation of neurons; GO:0051962 positive regulation of nervous system development; GO:0044763 single-organism cellular process; GO:0034249 negative regulation of cellular amide metabolic process; GO:0048522 positive regulation of cellular process; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0032501 multicellular organismal process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0045664 regulation of neuron differentiation; GO:0032269 negative regulation of cellular protein metabolic process; GO:0060999 positive regulation of dendritic spine development; GO:0019222 regulation of metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0051094 positive regulation of developmental process; GO:0048856 anatomical structure development; GO:0010975 regulation of neuron projection development; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:2000026 regulation of multicellular organismal development; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0061001 regulation of dendritic spine morphogenesis; GO:0060255 regulation of macromolecule metabolic process; GO:0010770 positive regulation of cell morphogenesis involved in differentiation; GO:0031344 regulation of cell projection organization; GO:0017148 negative regulation of translation; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0051239 regulation of multicellular organismal process; GO:0048814 regulation of dendrite morphogenesis; GO:0045597 positive regulation of cell differentiation; GO:1900006 positive regulation of dendrite development; GO:0030154 cell differentiation; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0061003 positive regulation of dendritic spine morphogenesis; GO:0045595 regulation of cell differentiation; GO:0010629 negative regulation of gene expression; GO:0048731 system development; GO:0051960 regulation of nervous system development; GO:0060284 regulation of cell development; GO:0010556 regulation of macromolecule biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0048518 positive regulation of biological process; GO:0034248 regulation of cellular amide metabolic process; GO:0050775 positive regulation of dendrite morphogenesis; GO:0009890 negative regulation of biosynthetic process; GO:0010976 positive regulation of neuron projection development; GO:0006417 regulation of translation; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0051248 negative regulation of protein metabolic process; GO:0050773 regulation of dendrite development; GO:0050769 positive regulation of neurogenesis; GO:0031327 negative regulation of cellular biosynthetic process; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:0051128 regulation of cellular component organization; GO:0022604 regulation of cell morphogenesis; GO:0050793 regulation of developmental process; GO:0065007 biological regulation; GO:0050767 regulation of neurogenesis; ","GO:0016020 membrane; GO:0030425 dendrite; GO:0071944 cell periphery; GO:0000932 P-body; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0043228 non-membrane-bounded organelle; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0043005 neuron projection; GO:0097458 neuron part; GO:0043229 intracellular organelle; GO:0010494 cytoplasmic stress granule; GO:0042995 cell projection; GO:0031226 intrinsic component of plasma membrane; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005829 cytosol; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0044459 plasma membrane part; GO:0035770 ribonucleoprotein granule; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005515 protein binding; GO:0005488 binding; GO:0003676 nucleic acid binding; ","K18743",null,null,"IPR022070; ","Cytoplasmic activation/proliferation-associated protein-1 C term; \r"]
["Q14554","Protein disulfide-isomerase A5 OS=Homo sapiens OX=9606 GN=PDIA5","PDIA5",59.594,10.143,5.6,3,4,3,1.191,1.102,1.277,0.695,0.894,0.864,0.687,0.0133,"extracellular\r","GO:0044700 single organism signaling; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0065008 regulation of biological quality; GO:0035967 cellular response to topologically incorrect protein; GO:0034976 response to endoplasmic reticulum stress; GO:0071310 cellular response to organic substance; GO:0045454 cell redox homeostasis; GO:0044699 single-organism process; GO:0036498 IRE1-mediated unfolded protein response; GO:0050896 response to stimulus; GO:0030968 endoplasmic reticulum unfolded protein response; GO:0006457 protein folding; GO:0042592 homeostatic process; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0035966 response to topologically incorrect protein; GO:0007154 cell communication; GO:0009987 cellular process; GO:0070887 cellular response to chemical stimulus; GO:0051716 cellular response to stimulus; GO:0006986 response to unfolded protein; GO:0006950 response to stress; GO:0034620 cellular response to unfolded protein; GO:0055114 oxidation-reduction process; GO:0044763 single-organism cellular process; GO:0019725 cellular homeostasis; GO:0010033 response to organic substance; GO:0023052 signaling; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0044710 single-organism metabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005788 endoplasmic reticulum lumen; GO:0043229 intracellular organelle; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044432 endoplasmic reticulum part; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds; GO:0005515 protein binding; GO:0016860 intramolecular oxidoreductase activity; GO:0016853 isomerase activity; GO:0003756 protein disulfide isomerase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016491 oxidoreductase activity; ","K09583",null,null,"IPR013766; IPR012336; ","Thioredoxin domain; Thioredoxin-like fold; \r"]
["Q14566","DNA replication licensing factor MCM6 OS=Homo sapiens OX=9606 GN=MCM6","MCM6",92.888,33.126,13.5,10,11,10,0.749,0.764,0.785,1.29,1.137,1.215,1.585,0.000297,"nucleus\r","GO:0016043 cellular component organization; GO:0006260 DNA replication; GO:0006268 DNA unwinding involved in DNA replication; GO:0006725 cellular aromatic compound metabolic process; GO:0006259 DNA metabolic process; GO:0032392 DNA geometric change; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:1903047 mitotic cell cycle process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0006270 DNA replication initiation; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0044770 cell cycle phase transition; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0000082 G1/S transition of mitotic cell cycle; GO:0006261 DNA-dependent DNA replication; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0044772 mitotic cell cycle phase transition; GO:0071103 DNA conformation change; GO:0000278 mitotic cell cycle; GO:0044843 cell cycle G1/S phase transition; GO:0032508 DNA duplex unwinding; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0090304 nucleic acid metabolic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0051276 chromosome organization; GO:0006996 organelle organization; GO:0044260 cellular macromolecule metabolic process; GO:0022402 cell cycle process; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0000784 nuclear chromosome, telomeric region; GO:0000781 chromosome, telomeric region; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0042555 MCM complex; GO:0005623 cell; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0098687 chromosomal region; GO:0043226 organelle; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044454 nuclear chromosome part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0000228 nuclear chromosome; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0003697 single-stranded DNA binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0042802 identical protein binding; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0003678 DNA helicase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003677 DNA binding; GO:0005524 ATP binding; GO:0004386 helicase activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003676 nucleic acid binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; ","K02542","MCM6; DNA replication licensing factor MCM6 [EC:3.6.4.12]","hsa04110 Cell cycle - Homo sapiens (human); hsa03030 DNA replication - Homo sapiens (human); ","IPR012340; IPR001208; IPR004039; IPR027417; IPR033762; IPR027925; ","\"Nucleic acid-binding, OB-fold; MCM domain; Rubredoxin-type fold; P-loop containing nucleoside triphosphate hydrolase; MCM OB domain; MCM N-terminal domain; \"\r"]
["Q14574","Desmocollin-3 OS=Homo sapiens OX=9606 GN=DSC3","DSC3",99.968,81.156,18.5,15,20,14,0.871,0.833,0.818,1.135,1.161,1.104,1.348,2.23E-4,"extracellular\r","GO:0044707 single-multicellular organism process; GO:0065008 regulation of biological quality; GO:0031424 keratinization; GO:0043009 chordate embryonic development; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0022610 biological adhesion; GO:0009913 epidermal cell differentiation; GO:0030154 cell differentiation; GO:0007155 cell adhesion; GO:0008544 epidermis development; GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules; GO:0007275 multicellular organism development; GO:0009790 embryo development; GO:0009987 cellular process; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0043588 skin development; GO:0009888 tissue development; GO:0030216 keratinocyte differentiation; GO:0048731 system development; GO:0070268 cornification; GO:0009792 embryo development ending in birth or egg hatching; GO:0044763 single-organism cellular process; GO:0098609 cell-cell adhesion; GO:0032501 multicellular organismal process; GO:0048513 animal organ development; GO:0008219 cell death; GO:0001701 in utero embryonic development; GO:0044767 single-organism developmental process; GO:0031647 regulation of protein stability; GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules; GO:0012501 programmed cell death; GO:0048856 anatomical structure development; GO:0050821 protein stabilization; GO:0065007 biological regulation; GO:0030855 epithelial cell differentiation; ","GO:0016020 membrane; GO:0001533 cornified envelope; GO:0071944 cell periphery; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0070161 anchoring junction; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0005911 cell-cell junction; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0030057 desmosome; ","GO:0045295 gamma-catenin binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0005509 calcium ion binding; GO:0005488 binding; GO:0043167 ion binding; ","K07602",null,null,"IPR015919; IPR027397; IPR000233; IPR014868; IPR002126; ","\"Cadherin-like; Catenin binding domain; Cadherin, cytoplasmic domain; Cadherin prodomain; Cadherin; \"\r"]
["Q14669","E3 ubiquitin-protein ligase TRIP12 OS=Homo sapiens OX=9606 GN=TRIP12","TRIP12",220.43,7.7423,1.8,3,4,3,0.907,0.938,1.053,1.035,0.961,1.106,1.07,0.323,"nucleus\r","GO:0051129 negative regulation of cellular component organization; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0031400 negative regulation of protein modification process; GO:0006282 regulation of DNA repair; GO:0031396 regulation of protein ubiquitination; GO:0008152 metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009790 embryo development; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:1900044 regulation of protein K63-linked ubiquitination; GO:0080090 regulation of primary metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0010639 negative regulation of organelle organization; GO:1901575 organic substance catabolic process; GO:2001021 negative regulation of response to DNA damage stimulus; GO:0045738 negative regulation of DNA repair; GO:0032268 regulation of cellular protein metabolic process; GO:0033182 regulation of histone ubiquitination; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0051052 regulation of DNA metabolic process; GO:0080135 regulation of cellular response to stress; GO:0032269 negative regulation of cellular protein metabolic process; GO:0030163 protein catabolic process; GO:0051053 negative regulation of DNA metabolic process; GO:1901315 negative regulation of histone H2A K63-linked ubiquitination; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006464 cellular protein modification process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:1905268 negative regulation of chromatin organization; GO:0031056 regulation of histone modification; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0033554 cellular response to stress; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:2000780 negative regulation of double-strand break repair; GO:0006725 cellular aromatic compound metabolic process; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:2001020 regulation of response to DNA damage stimulus; GO:0006259 DNA metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0031399 regulation of protein modification process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0080134 regulation of response to stress; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0000209 protein polyubiquitination; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0006508 proteolysis; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0033183 negative regulation of histone ubiquitination; GO:0031397 negative regulation of protein ubiquitination; GO:0043632 modification-dependent macromolecule catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0016567 protein ubiquitination; GO:0006950 response to stress; GO:0019941 modification-dependent protein catabolic process; GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:1902275 regulation of chromatin organization; GO:0033043 regulation of organelle organization; GO:0006807 nitrogen compound metabolic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0048585 negative regulation of response to stimulus; GO:0044238 primary metabolic process; GO:1900045 negative regulation of protein K63-linked ubiquitination; GO:0009892 negative regulation of metabolic process; GO:2000779 regulation of double-strand break repair; GO:0033044 regulation of chromosome organization; GO:0006974 cellular response to DNA damage stimulus; GO:0031057 negative regulation of histone modification; GO:1903321 negative regulation of protein modification by small protein conjugation or removal; GO:1902914 regulation of protein polyubiquitination; GO:0006281 DNA repair; GO:2001251 negative regulation of chromosome organization; GO:0032446 protein modification by small protein conjugation; GO:1901314 regulation of histone H2A K63-linked ubiquitination; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0009057 macromolecule catabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0051128 regulation of cellular component organization; GO:0043412 macromolecule modification; GO:0009056 catabolic process; GO:1902915 negative regulation of protein polyubiquitination; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0046966 thyroid hormone receptor binding; GO:0019787 ubiquitin-like protein transferase activity; GO:0003824 catalytic activity; GO:0005102 receptor binding; GO:0005488 binding; GO:0004842 ubiquitin-protein transferase activity; GO:0035257 nuclear hormone receptor binding; GO:0005515 protein binding; GO:0051427 hormone receptor binding; GO:0016740 transferase activity; GO:0008134 transcription factor binding; ","K10590","TRIP12; E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26]","hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human); ","IPR004170; IPR011989; IPR016024; IPR000569; ","WWE domain; Armadillo-like helical; Armadillo-type fold; HECT domain; \r"]
["Q14683","Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A","SMC1A",143.23,35.461,9.3,12,14,12,0.949,0.938,0.906,1.113,1.05,1.071,1.158,2.66E-3,"cytoplasm\r","GO:0044700 single organism signaling; GO:0022414 reproductive process; GO:0007067 mitotic nuclear division; GO:0044699 single-organism process; GO:0090329 regulation of DNA-dependent DNA replication; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0000819 sister chromatid segregation; GO:0007165 signal transduction; GO:0045930 negative regulation of mitotic cell cycle; GO:0007154 cell communication; GO:0044702 single organism reproductive process; GO:0000075 cell cycle checkpoint; GO:0009314 response to radiation; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0043170 macromolecule metabolic process; GO:0051726 regulation of cell cycle; GO:0032502 developmental process; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0007059 chromosome segregation; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0051321 meiotic cell cycle; GO:0031323 regulation of cellular metabolic process; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0032501 multicellular organismal process; GO:0008156 negative regulation of DNA replication; GO:1902589 single-organism organelle organization; GO:0000226 microtubule cytoskeleton organization; GO:0010948 negative regulation of cell cycle process; GO:0050789 regulation of biological process; GO:0051052 regulation of DNA metabolic process; GO:0090304 nucleic acid metabolic process; GO:0051053 negative regulation of DNA metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0098727 maintenance of cell number; GO:0019222 regulation of metabolic process; GO:1902850 microtubule cytoskeleton organization involved in mitosis; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0051301 cell division; GO:2000104 negative regulation of DNA-dependent DNA replication; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0000003 reproduction; GO:0016043 cellular component organization; GO:0033554 cellular response to stress; GO:0044707 single-multicellular organism process; GO:0007346 regulation of mitotic cell cycle; GO:0045786 negative regulation of cell cycle; GO:1903046 meiotic cell cycle process; GO:0006275 regulation of DNA replication; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0009628 response to abiotic stimulus; GO:0006259 DNA metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0048285 organelle fission; GO:0007051 spindle organization; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:1903047 mitotic cell cycle process; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0007093 mitotic cell cycle checkpoint; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0042770 signal transduction in response to DNA damage; GO:0019827 stem cell population maintenance; GO:0007010 cytoskeleton organization; GO:0007052 mitotic spindle organization; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0009987 cellular process; GO:0032875 regulation of DNA endoreduplication; GO:0006950 response to stress; GO:0035556 intracellular signal transduction; GO:0006807 nitrogen compound metabolic process; GO:0000070 mitotic sister chromatid segregation; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0007017 microtubule-based process; GO:0006974 cellular response to DNA damage stimulus; GO:0007064 mitotic sister chromatid cohesion; GO:0009890 negative regulation of biosynthetic process; GO:0006281 DNA repair; GO:0051276 chromosome organization; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0098813 nuclear chromosome segregation; GO:0000280 nuclear division; GO:0007126 meiotic nuclear division; GO:0031327 negative regulation of cellular biosynthetic process; GO:0022402 cell cycle process; GO:0007062 sister chromatid cohesion; GO:0032876 negative regulation of DNA endoreduplication; GO:0007049 cell cycle; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0030893 meiotic cohesin complex; GO:0000777 condensed chromosome kinetochore; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0000793 condensed chromosome; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0005694 chromosome; GO:0043227 membrane-bounded organelle; GO:0000776 kinetochore; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0000779 condensed chromosome, centromeric region; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0008278 cohesin complex; GO:0043226 organelle; GO:0098687 chromosomal region; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0000775 chromosome, centromeric region; GO:0000228 nuclear chromosome; GO:0000794 condensed nuclear chromosome; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0003723 RNA binding; GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0046982 protein heterodimerization activity; GO:0044877 macromolecular complex binding; GO:0046983 protein dimerization activity; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0003682 chromatin binding; GO:0036033 mediator complex binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0032550 purine ribonucleoside binding; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0032403 protein complex binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K06636","SMC1; structural maintenance of chromosome 1","hsa04110 Cell cycle - Homo sapiens (human); hsa04114 Oocyte meiosis - Homo sapiens (human); ","IPR010935; IPR027417; IPR003395; ","\"SMCs flexible hinge; P-loop containing nucleoside triphosphate hydrolase; RecF/RecN/SMC, N-terminal; \"\r"]
["Q14696","LRP chaperone MESD OS=Homo sapiens OX=9606 GN=MESD","MESD",26.076,39.569,11.5,2,2,2,1.185,1.126,0.802,0.904,1.055,0.947,0.934,0.688,"extracellular\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0009888 tissue development; GO:0007166 cell surface receptor signaling pathway; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0023052 signaling; GO:0050896 response to stimulus; GO:0051641 cellular localization; GO:0198738 cell-cell signaling by wnt; GO:0007498 mesoderm development; GO:0006457 protein folding; GO:0070727 cellular macromolecule localization; GO:0007165 signal transduction; GO:0050789 regulation of biological process; GO:0007267 cell-cell signaling; GO:0007154 cell communication; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0034613 cellular protein localization; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0051179 localization; GO:0016055 Wnt signaling pathway; GO:0009987 cellular process; GO:0048856 anatomical structure development; GO:0034394 protein localization to cell surface; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0043229 intracellular organelle; GO:0005783 endoplasmic reticulum; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0070325 lipoprotein particle receptor binding; GO:0005102 receptor binding; GO:0050750 low-density lipoprotein particle receptor binding; GO:0005488 binding; "]
["Q14738","Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform OS=Homo sapiens OX=9606 GN=PPP2R5D","PPP2R5D",69.991,13.525,6.1,3,3,3,1.051,0.971,1.123,0.866,1.008,0.989,0.91,0.212,"nucleus\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0044707 single-multicellular organism process; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0048731 system development; GO:0023052 signaling; GO:0044238 primary metabolic process; GO:0006470 protein dephosphorylation; GO:0032501 multicellular organismal process; GO:0016311 dephosphorylation; GO:0050789 regulation of biological process; GO:0006793 phosphorus metabolic process; GO:0044767 single-organism developmental process; GO:0050790 regulation of catalytic activity; GO:0044260 cellular macromolecule metabolic process; GO:0065009 regulation of molecular function; GO:0006464 cellular protein modification process; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0008287 protein serine/threonine phosphatase complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:1903293 phosphatase complex; GO:0044422 organelle part; GO:0000159 protein phosphatase type 2A complex; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0030234 enzyme regulator activity; GO:0003824 catalytic activity; GO:0042578 phosphoric ester hydrolase activity; GO:0004722 protein serine/threonine phosphatase activity; GO:0016791 phosphatase activity; GO:0019888 protein phosphatase regulator activity; GO:0019208 phosphatase regulator activity; GO:0005488 binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0004721 phosphoprotein phosphatase activity; GO:0098772 molecular function regulator; ","K11584","PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'","hsa04728 Dopaminergic synapse - Homo sapiens (human); hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human); hsa04071 Sphingolipid signaling pathway - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa04152 AMPK signaling pathway - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa03015 mRNA surveillance pathway - Homo sapiens (human); hsa04114 Oocyte meiosis - Homo sapiens (human); ","IPR016024; ","Armadillo-type fold; \r"]
["Q14764","Major vault protein OS=Homo sapiens OX=9606 GN=MVP","MVP",99.326,143.65,35.8,26,50,26,0.943,0.976,0.98,1.047,1.059,1.031,1.082,0.00546,"cytoplasm\r","GO:0044700 single organism signaling; GO:0050658 RNA transport; GO:0045321 leukocyte activation; GO:0007166 cell surface receptor signaling pathway; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0031400 negative regulation of protein modification process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0050657 nucleic acid transport; GO:0033673 negative regulation of kinase activity; GO:0015931 nucleobase-containing compound transport; GO:0038127 ERBB signaling pathway; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0002443 leukocyte mediated immunity; GO:0080090 regulation of primary metabolic process; GO:0002446 neutrophil mediated immunity; GO:0061097 regulation of protein tyrosine kinase activity; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0051348 negative regulation of transferase activity; GO:0023052 signaling; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0006810 transport; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0032940 secretion by cell; GO:0065009 regulation of molecular function; GO:0006469 negative regulation of protein kinase activity; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0043299 leukocyte degranulation; GO:0043549 regulation of kinase activity; GO:0045859 regulation of protein kinase activity; GO:0050794 regulation of cellular process; GO:0002283 neutrophil activation involved in immune response; GO:0050730 regulation of peptidyl-tyrosine phosphorylation; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0051028 mRNA transport; GO:0031399 regulation of protein modification process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0051236 establishment of RNA localization; GO:0023057 negative regulation of signaling; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0042326 negative regulation of phosphorylation; GO:0061099 negative regulation of protein tyrosine kinase activity; GO:0051338 regulation of transferase activity; GO:0001933 negative regulation of protein phosphorylation; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0006403 RNA localization; GO:0016192 vesicle-mediated transport; GO:0001932 regulation of protein phosphorylation; GO:0002376 immune system process; GO:0071702 organic substance transport; GO:0031952 regulation of protein autophosphorylation; GO:0043312 neutrophil degranulation; GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation; GO:0002263 cell activation involved in immune response; GO:0009892 negative regulation of metabolic process; GO:0002366 leukocyte activation involved in immune response; GO:0045184 establishment of protein localization; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0051246 regulation of protein metabolic process; GO:0031953 negative regulation of protein autophosphorylation; GO:0010563 negative regulation of phosphorus metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0001775 cell activation; GO:0051179 localization; GO:0006955 immune response; GO:0045936 negative regulation of phosphate metabolic process; GO:0071705 nitrogen compound transport; GO:0006887 exocytosis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0034774 secretory granule lumen; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0005643 nuclear pore; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005635 nuclear envelope; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0031975 envelope; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0042802 identical protein binding; GO:0019903 protein phosphatase binding; GO:0005488 binding; GO:0019901 protein kinase binding; GO:0005515 protein binding; GO:0019902 phosphatase binding; GO:0019900 kinase binding; GO:0019899 enzyme binding; ","K17266",null,null,"IPR021870; ","\"Major vault protein, shoulder domain; \"\r"]
["Q14847","LIM and SH3 domain protein 1 OS=Homo sapiens OX=9606 GN=LASP1","LASP1",29.717,41.5,45.2,13,22,13,0.961,0.985,0.99,0.999,1.027,0.991,1.028,0.128,"nucleus\r","GO:0050794 regulation of cellular process; GO:0034220 ion transmembrane transport; GO:0023051 regulation of signaling; GO:0048522 positive regulation of cellular process; GO:0048518 positive regulation of biological process; GO:0051234 establishment of localization; GO:0006810 transport; GO:0055085 transmembrane transport; GO:0010646 regulation of cell communication; GO:0050789 regulation of biological process; GO:0006811 ion transport; GO:0023056 positive regulation of signaling; GO:0048583 regulation of response to stimulus; GO:0010647 positive regulation of cell communication; GO:0009967 positive regulation of signal transduction; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0009966 regulation of signal transduction; GO:0065007 biological regulation; ","GO:0044421 extracellular region part; GO:0005938 cell cortex; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0099568 cytoplasmic region; GO:0030863 cortical cytoskeleton; GO:0030864 cortical actin cytoskeleton; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005856 cytoskeleton; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0015629 actin cytoskeleton; GO:0005576 extracellular region; GO:0043226 organelle; GO:0044448 cell cortex part; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0051015 actin filament binding; GO:0030674 protein binding, bridging; GO:0015075 ion transmembrane transporter activity; GO:0043167 ion binding; GO:0044877 macromolecular complex binding; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0008270 zinc ion binding; GO:0022891 substrate-specific transmembrane transporter activity; GO:0050839 cell adhesion molecule binding; GO:0005070 SH3/SH2 adaptor activity; GO:0008092 cytoskeletal protein binding; GO:0035591 signaling adaptor activity; GO:0046914 transition metal ion binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0003779 actin binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0060090 binding, bridging; GO:0032403 protein complex binding; GO:0022857 transmembrane transporter activity; GO:0005215 transporter activity; ",{"$nulls":3},"IPR001781; IPR001452; ","\"Zinc finger, LIM-type; SH3 domain; \"\r"]
["Q14894","Ketimine reductase mu-crystallin OS=Homo sapiens OX=9606 GN=CRYM","CRYM",33.775,8.3005,4.8,1,1,1,0.843,1.01,1.141,1.027,0.902,1.081,1.005,0.927,"cyto_nucl\r","GO:1901606 alpha-amino acid catabolic process; GO:0065008 regulation of biological quality; GO:0009914 hormone transport; GO:0072337 modified amino acid transport; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0051253 negative regulation of RNA metabolic process; GO:0050877 neurological system process; GO:0051234 establishment of localization; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0044765 single-organism transport; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0010468 regulation of gene expression; GO:0042445 hormone metabolic process; GO:0007600 sensory perception; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0000122 negative regulation of transcription from RNA polymerase II promoter; GO:1901360 organic cyclic compound metabolic process; GO:0070327 thyroid hormone transport; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0046395 carboxylic acid catabolic process; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0009068 aspartate family amino acid catabolic process; GO:0050789 regulation of biological process; GO:0018958 phenol-containing compound metabolic process; GO:0044710 single-organism metabolic process; GO:1902679 negative regulation of RNA biosynthetic process; GO:0010817 regulation of hormone levels; GO:0019222 regulation of metabolic process; GO:0009063 cellular amino acid catabolic process; GO:0006554 lysine catabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0006082 organic acid metabolic process; GO:0043436 oxoacid metabolic process; GO:0042403 thyroid hormone metabolic process; GO:0050954 sensory perception of mechanical stimulus; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0006725 cellular aromatic compound metabolic process; GO:1901615 organic hydroxy compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0009066 aspartate family amino acid metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0071704 organic substance metabolic process; GO:0045892 negative regulation of transcription, DNA-templated; GO:0006575 cellular modified amino acid metabolic process; GO:1902578 single-organism localization; GO:0009889 regulation of biosynthetic process; GO:0044248 cellular catabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0009987 cellular process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0003008 system process; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0044712 single-organism catabolic process; GO:0006553 lysine metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0071702 organic substance transport; GO:0044282 small molecule catabolic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0044238 primary metabolic process; GO:1901605 alpha-amino acid metabolic process; GO:0009892 negative regulation of metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0009890 negative regulation of biosynthetic process; GO:1901565 organonitrogen compound catabolic process; GO:0019752 carboxylic acid metabolic process; GO:0016054 organic acid catabolic process; GO:0007605 sensory perception of sound; GO:0031327 negative regulation of cellular biosynthetic process; GO:0051179 localization; GO:0009056 catabolic process; GO:0071705 nitrogen compound transport; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0044439 peroxisomal part; GO:0005777 peroxisome; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044438 microbody part; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005634 nucleus; GO:0031907 microbody lumen; GO:0070013 intracellular organelle lumen; GO:0005782 peroxisomal matrix; GO:0005622 intracellular; GO:0044464 cell part; GO:0042579 microbody; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; ","GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors; GO:0003714 transcription corepressor activity; GO:1901265 nucleoside phosphate binding; GO:0042562 hormone binding; GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0003712 transcription cofactor activity; GO:0048037 cofactor binding; GO:0016491 oxidoreductase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0047127 thiomorpholine-carboxylate dehydrogenase activity; GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0050661 NADP binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0070324 thyroid hormone binding; GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors; GO:0000988 transcription factor activity, protein binding; GO:0036094 small molecule binding; GO:0050662 coenzyme binding; ","K18258",null,null,"IPR023401; IPR016040; ","\"Ornithine cyclodeaminase, N-terminal; NAD(P)-binding domain; \"\r"]
["Q14934","Nuclear factor of activated T-cells, cytoplasmic 4 OS=Homo sapiens OX=9606 GN=NFATC4","NFATC4",95.448,2.5148,1,1,2,1,0.973,1.036,1.024,1.126,1.097,0.761,0.984,0.83,"nucleus\r","GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:2000171 negative regulation of dendrite development; GO:0032680 regulation of tumor necrosis factor production; GO:0009891 positive regulation of biosynthetic process; GO:0032091 negative regulation of protein binding; GO:0044237 cellular metabolic process; GO:0048754 branching morphogenesis of an epithelial tube; GO:0008152 metabolic process; GO:0001525 angiogenesis; GO:0006091 generation of precursor metabolites and energy; GO:0001569 branching involved in blood vessel morphogenesis; GO:0051716 cellular response to stimulus; GO:0071214 cellular response to abiotic stimulus; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0035239 tube morphogenesis; GO:0001763 morphogenesis of a branching structure; GO:0044763 single-organism cellular process; GO:0019932 second-messenger-mediated signaling; GO:0071396 cellular response to lipid; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0045665 negative regulation of neuron differentiation; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0010721 negative regulation of cell development; GO:0010975 regulation of neuron projection development; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0055001 muscle cell development; GO:0072359 circulatory system development; GO:0002009 morphogenesis of an epithelium; GO:0044707 single-multicellular organism process; GO:0097190 apoptotic signaling pathway; GO:0001819 positive regulation of cytokine production; GO:1901700 response to oxygen-containing compound; GO:0048519 negative regulation of biological process; GO:0071362 cellular response to ether; GO:0048814 regulation of dendrite morphogenesis; GO:0045892 negative regulation of transcription, DNA-templated; GO:0045472 response to ether; GO:0009653 anatomical structure morphogenesis; GO:0023057 negative regulation of signaling; GO:0046483 heterocycle metabolic process; GO:0010648 negative regulation of cell communication; GO:0071229 cellular response to acid chemical; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0031345 negative regulation of cell projection organization; GO:0061061 muscle structure development; GO:1902680 positive regulation of RNA biosynthetic process; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0060562 epithelial tube morphogenesis; GO:0010771 negative regulation of cell morphogenesis involved in differentiation; GO:0006950 response to stress; GO:0009416 response to light stimulus; GO:0050804 modulation of synaptic transmission; GO:0051960 regulation of nervous system development; GO:0060284 regulation of cell development; GO:0010977 negative regulation of neuron projection development; GO:0010033 response to organic substance; GO:1901576 organic substance biosynthetic process; GO:1904636 response to ionomycin; GO:0006974 cellular response to DNA damage stimulus; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage; GO:0009890 negative regulation of biosynthetic process; GO:0031325 positive regulation of cellular metabolic process; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:0051093 negative regulation of developmental process; GO:0009968 negative regulation of signal transduction; GO:0001568 blood vessel development; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0051253 negative regulation of RNA metabolic process; GO:0033173 calcineurin-NFAT signaling cascade; GO:2001141 regulation of RNA biosynthetic process; GO:0048729 tissue morphogenesis; GO:0007165 signal transduction; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0006915 apoptotic process; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0090128 regulation of synapse maturation; GO:0010226 response to lithium ion; GO:0031326 regulation of cellular biosynthetic process; GO:0055114 oxidation-reduction process; GO:0051098 regulation of binding; GO:0001944 vasculature development; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0010038 response to metal ion; GO:0010942 positive regulation of cell death; GO:0006351 transcription, DNA-templated; GO:0045664 regulation of neuron differentiation; GO:0006954 inflammatory response; GO:1902679 negative regulation of RNA biosynthetic process; GO:1902893 regulation of pri-miRNA transcription from RNA polymerase II promoter; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0006952 defense response; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0043065 positive regulation of apoptotic process; GO:0048016 inositol phosphate-mediated signaling; GO:0097193 intrinsic apoptotic signaling pathway; GO:0071704 organic substance metabolic process; GO:0033993 response to lipid; GO:0030154 cell differentiation; GO:0051961 negative regulation of nervous system development; GO:0023056 positive regulation of signaling; GO:2001235 positive regulation of apoptotic signaling pathway; GO:0034641 cellular nitrogen compound metabolic process; GO:0010647 positive regulation of cell communication; GO:0009059 macromolecule biosynthetic process; GO:0071478 cellular response to radiation; GO:0045595 regulation of cell differentiation; GO:0050803 regulation of synapse structure or activity; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0035556 intracellular signal transduction; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0044249 cellular biosynthetic process; GO:0035561 regulation of chromatin binding; GO:1901701 cellular response to oxygen-containing compound; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0008219 cell death; GO:0006366 transcription from RNA polymerase II promoter; GO:1904637 cellular response to ionomycin; GO:0001817 regulation of cytokine production; GO:0042692 muscle cell differentiation; GO:0010467 gene expression; GO:0031327 negative regulation of cellular biosynthetic process; GO:0042981 regulation of apoptotic process; GO:0050767 regulation of neurogenesis; GO:0065008 regulation of biological quality; GO:0097659 nucleic acid-templated transcription; GO:0034644 cellular response to UV; GO:0032760 positive regulation of tumor necrosis factor production; GO:0050807 regulation of synapse organization; GO:0007507 heart development; GO:0050774 negative regulation of dendrite morphogenesis; GO:0051240 positive regulation of multicellular organismal process; GO:0097720 calcineurin-mediated signaling; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0043170 macromolecule metabolic process; GO:0007399 nervous system development; GO:0014070 response to organic cyclic compound; GO:0018130 heterocycle biosynthetic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0071398 cellular response to fatty acid; GO:0000122 negative regulation of transcription from RNA polymerase II promoter; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0071482 cellular response to light stimulus; GO:0050768 negative regulation of neurogenesis; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0044710 single-organism metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0043068 positive regulation of programmed cell death; GO:1901362 organic cyclic compound biosynthetic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0009628 response to abiotic stimulus; GO:0043067 regulation of programmed cell death; GO:0048523 negative regulation of cellular process; GO:0051239 regulation of multicellular organismal process; GO:0019722 calcium-mediated signaling; GO:0019438 aromatic compound biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0051171 regulation of nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter; GO:0070542 response to fatty acid; GO:0048167 regulation of synaptic plasticity; GO:0051254 positive regulation of RNA metabolic process; GO:0048731 system development; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1903557 positive regulation of tumor necrosis factor superfamily cytokine production; GO:0072358 cardiovascular system development; GO:0071407 cellular response to organic cyclic compound; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0061138 morphogenesis of a branching epithelium; GO:0030111 regulation of Wnt signaling pathway; GO:0051145 smooth muscle cell differentiation; GO:0012501 programmed cell death; GO:0048584 positive regulation of response to stimulus; GO:0031328 positive regulation of cellular biosynthetic process; GO:0071248 cellular response to metal ion; GO:0050793 regulation of developmental process; GO:1903555 regulation of tumor necrosis factor superfamily cytokine production; GO:0001101 response to acid chemical; GO:0051129 negative regulation of cellular component organization; GO:0022008 neurogenesis; GO:0051241 negative regulation of multicellular organismal process; GO:2001233 regulation of apoptotic signaling pathway; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0009314 response to radiation; GO:0048514 blood vessel morphogenesis; GO:0010035 response to inorganic substance; GO:0045596 negative regulation of cell differentiation; GO:0035562 negative regulation of chromatin binding; GO:0070887 cellular response to chemical stimulus; GO:0071285 cellular response to lithium ion; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0060429 epithelium development; GO:0035295 tube development; GO:0009888 tissue development; GO:0030178 negative regulation of Wnt signaling pathway; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0016070 RNA metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0090304 nucleic acid metabolic process; GO:0051100 negative regulation of binding; GO:0015980 energy derivation by oxidation of organic compounds; GO:0019222 regulation of metabolic process; GO:0071241 cellular response to inorganic substance; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0006725 cellular aromatic compound metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031344 regulation of cell projection organization; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0043393 regulation of protein binding; GO:0009987 cellular process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0045333 cellular respiration; GO:0009411 response to UV; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:1905809 negative regulation of synapse organization; GO:0050773 regulation of dendrite development; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:2000297 negative regulation of synapse maturation; GO:0009967 positive regulation of signal transduction; GO:0051128 regulation of cellular component organization; GO:0022604 regulation of cell morphogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005667 transcription factor complex; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0005622 intracellular; GO:0044464 cell part; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0003677 DNA binding; GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding; GO:0005102 receptor binding; GO:0000976 transcription regulatory region sequence-specific DNA binding; GO:0003690 double-stranded DNA binding; GO:1990837 sequence-specific double-stranded DNA binding; GO:0001012 RNA polymerase II regulatory region DNA binding; GO:0005515 protein binding; GO:0003712 transcription cofactor activity; GO:0043565 sequence-specific DNA binding; GO:0000987 core promoter proximal region sequence-specific DNA binding; GO:0003700 transcription factor activity, sequence-specific DNA binding; GO:1901363 heterocyclic compound binding; GO:0001159 core promoter proximal region DNA binding; GO:0097159 organic cyclic compound binding; GO:0000975 regulatory region DNA binding; GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding; GO:0001067 regulatory region nucleic acid binding; GO:0044212 transcription regulatory region DNA binding; GO:0005488 binding; GO:0042975 peroxisome proliferator activated receptor binding; GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding; GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding; GO:0003676 nucleic acid binding; GO:0001071 nucleic acid binding transcription factor activity; GO:0000989 transcription factor activity, transcription factor binding; GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding; GO:0003713 transcription coactivator activity; GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding; GO:0000988 transcription factor activity, protein binding; GO:0008134 transcription factor binding; ","K17334","NFATC4; nuclear factor of activated T-cells, cytoplasmic 4","hsa04921 Oxytocin signaling pathway - Homo sapiens (human); hsa04218 Cellular senescence - Homo sapiens (human); hsa04625 C-type lectin receptor signaling pathway - Homo sapiens (human); hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human); hsa05167 Kaposi's sarcoma-associated herpesvirus infection - Homo sapiens (human); hsa05166 HTLV-I infection - Homo sapiens (human); hsa05161 Hepatitis B - Homo sapiens (human); hsa04360 Axon guidance - Homo sapiens (human); hsa04310 Wnt signaling pathway - Homo sapiens (human); ","IPR013783; IPR014756; IPR008967; IPR011539; IPR032397; IPR002909; ","\"Immunoglobulin-like fold; Immunoglobulin E-set; p53-like transcription factor, DNA-binding; Rel homology domain (RHD), DNA-binding domain; Rel homology dimerisation domain; IPT domain; \"\r"]
["Q14956","Transmembrane glycoprotein NMB OS=Homo sapiens OX=9606 GN=GPNMB","GPNMB",63.922,15.681,6.5,3,8,3,1.159,1.01,1.136,0.923,0.949,0.844,0.822,0.0245,"peroxisome\r","GO:0044700 single organism signaling; GO:0002694 regulation of leukocyte activation; GO:0050672 negative regulation of lymphocyte proliferation; GO:0001649 osteoblast differentiation; GO:1902807 negative regulation of cell cycle G1/S phase transition; GO:0030335 positive regulation of cell migration; GO:0010941 regulation of cell death; GO:0032944 regulation of mononuclear cell proliferation; GO:0032270 positive regulation of cellular protein metabolic process; GO:0032680 regulation of tumor necrosis factor production; GO:0010564 regulation of cell cycle process; GO:0008285 negative regulation of cell proliferation; GO:0009605 response to external stimulus; GO:0022610 biological adhesion; GO:0070664 negative regulation of leukocyte proliferation; GO:0032879 regulation of localization; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0007155 cell adhesion; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:1903038 negative regulation of leukocyte cell-cell adhesion; GO:0001503 ossification; GO:2000134 negative regulation of G1/S transition of mitotic cell cycle; GO:0044763 single-organism cellular process; GO:0050670 regulation of lymphocyte proliferation; GO:0051272 positive regulation of cellular component movement; GO:0031323 regulation of cellular metabolic process; GO:0006935 chemotaxis; GO:0032501 multicellular organismal process; GO:0030282 bone mineralization; GO:0048513 animal organ development; GO:0010948 negative regulation of cell cycle process; GO:0007267 cell-cell signaling; GO:0048583 regulation of response to stimulus; GO:0010604 positive regulation of macromolecule metabolic process; GO:0042330 taxis; GO:0045765 regulation of angiogenesis; GO:0002682 regulation of immune system process; GO:0060548 negative regulation of cell death; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0007346 regulation of mitotic cell cycle; GO:0007162 negative regulation of cell adhesion; GO:0042127 regulation of cell proliferation; GO:0031399 regulation of protein modification process; GO:0022408 negative regulation of cell-cell adhesion; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:2000147 positive regulation of cell motility; GO:0051239 regulation of multicellular organismal process; GO:0050866 negative regulation of cell activation; GO:0070372 regulation of ERK1 and ERK2 cascade; GO:1901987 regulation of cell cycle phase transition; GO:2000145 regulation of cell motility; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:0031214 biomineral tissue development; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:1901215 negative regulation of neuron death; GO:1902531 regulation of intracellular signal transduction; GO:0051270 regulation of cellular component movement; GO:0032720 negative regulation of tumor necrosis factor production; GO:0048731 system development; GO:0030334 regulation of cell migration; GO:0030155 regulation of cell adhesion; GO:0051247 positive regulation of protein metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0048584 positive regulation of response to stimulus; GO:0050793 regulation of developmental process; GO:2000045 regulation of G1/S transition of mitotic cell cycle; GO:0050863 regulation of T cell activation; GO:1903555 regulation of tumor necrosis factor superfamily cytokine production; GO:0040017 positive regulation of locomotion; GO:0031954 positive regulation of protein autophosphorylation; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0051241 negative regulation of multicellular organismal process; GO:0042130 negative regulation of T cell proliferation; GO:0034103 regulation of tissue remodeling; GO:0001818 negative regulation of cytokine production; GO:0051249 regulation of lymphocyte activation; GO:0045930 negative regulation of mitotic cell cycle; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:1901991 negative regulation of mitotic cell cycle phase transition; GO:1902806 regulation of cell cycle G1/S phase transition; GO:0070663 regulation of leukocyte proliferation; GO:0002695 negative regulation of leukocyte activation; GO:0051726 regulation of cell cycle; GO:0032502 developmental process; GO:0045937 positive regulation of phosphate metabolic process; GO:0009888 tissue development; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0002683 negative regulation of immune system process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0050865 regulation of cell activation; GO:0019222 regulation of metabolic process; GO:0040011 locomotion; GO:0019220 regulation of phosphate metabolic process; GO:0050868 negative regulation of T cell activation; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0045786 negative regulation of cell cycle; GO:0051250 negative regulation of lymphocyte activation; GO:1901988 negative regulation of cell cycle phase transition; GO:0060255 regulation of macromolecule metabolic process; GO:0050896 response to stimulus; GO:0030154 cell differentiation; GO:0043408 regulation of MAPK cascade; GO:0023056 positive regulation of signaling; GO:1903556 negative regulation of tumor necrosis factor superfamily cytokine production; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:0050918 positive chemotaxis; GO:1901214 regulation of neuron death; GO:0001932 regulation of protein phosphorylation; GO:1901342 regulation of vasculature development; GO:0031401 positive regulation of protein modification process; GO:0032945 negative regulation of mononuclear cell proliferation; GO:0042129 regulation of T cell proliferation; GO:0031952 regulation of protein autophosphorylation; GO:0001934 positive regulation of protein phosphorylation; GO:0048518 positive regulation of biological process; GO:0022407 regulation of cell-cell adhesion; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0001817 regulation of cytokine production; GO:0009967 positive regulation of signal transduction; GO:0043410 positive regulation of MAPK cascade; GO:0040012 regulation of locomotion; GO:0070374 positive regulation of ERK1 and ERK2 cascade; GO:0065007 biological regulation; ","GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0031226 intrinsic component of plasma membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0042470 melanosome; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0048770 pigment granule; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0030546 receptor activator activity; GO:0048018 receptor agonist activity; GO:0005102 receptor binding; GO:0043394 proteoglycan binding; GO:0043167 ion binding; GO:0044877 macromolecular complex binding; GO:0005178 integrin binding; GO:0005515 protein binding; GO:0008201 heparin binding; GO:0098772 molecular function regulator; GO:1901681 sulfur compound binding; GO:0004871 signal transducer activity; GO:0042056 chemoattractant activity; GO:0050839 cell adhesion molecule binding; GO:0045545 syndecan binding; GO:0097367 carbohydrate derivative binding; GO:0030545 receptor regulator activity; GO:0005488 binding; GO:0043168 anion binding; GO:0001948 glycoprotein binding; GO:0005539 glycosaminoglycan binding; GO:0032403 protein complex binding; ","K20732",null,null,"IPR022409; IPR000601; ","PKD/Chitinase domain; PKD domain; \r"]
["Q14997","Proteasome activator complex subunit 4 OS=Homo sapiens OX=9606 GN=PSME4","PSME4",211.33,4.9811,1.1,2,3,2,0.993,0.945,1.007,0.959,1.023,1.075,1.038,0.393,"nucleus\r","GO:0044700 single organism signaling; GO:0022414 reproductive process; GO:0010608 posttranscriptional regulation of gene expression; GO:0051443 positive regulation of ubiquitin-protein transferase activity; GO:0031347 regulation of defense response; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:1903364 positive regulation of cellular protein catabolic process; GO:0008152 metabolic process; GO:0007286 spermatid development; GO:0044093 positive regulation of molecular function; GO:0090263 positive regulation of canonical Wnt signaling pathway; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0016055 Wnt signaling pathway; GO:0051716 cellular response to stimulus; GO:0010499 proteasomal ubiquitin-independent protein catabolic process; GO:0006521 regulation of cellular amino acid metabolic process; GO:0080090 regulation of primary metabolic process; GO:0010972 negative regulation of G2/M transition of mitotic cell cycle; GO:0044763 single-organism cellular process; GO:0060828 regulation of canonical Wnt signaling pathway; GO:0033209 tumor necrosis factor-mediated signaling pathway; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0000165 MAPK cascade; GO:1901575 organic substance catabolic process; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0007267 cell-cell signaling; GO:0002223 stimulatory C-type lectin receptor signaling pathway; GO:0030163 protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0060071 Wnt signaling pathway, planar cell polarity pathway; GO:0048609 multicellular organismal reproductive process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0000003 reproduction; GO:0034728 nucleosome organization; GO:0016310 phosphorylation; GO:0044707 single-multicellular organism process; GO:0043486 histone exchange; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0006259 DNA metabolic process; GO:0048519 negative regulation of biological process; GO:0043487 regulation of RNA stability; GO:0000209 protein polyubiquitination; GO:0023057 negative regulation of signaling; GO:0046483 heterocycle metabolic process; GO:0010648 negative regulation of cell communication; GO:0051345 positive regulation of hydrolase activity; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0009896 positive regulation of catabolic process; GO:0043620 regulation of DNA-templated transcription in response to stress; GO:0070482 response to oxygen levels; GO:0044248 cellular catabolic process; GO:0042176 regulation of protein catabolic process; GO:0038093 Fc receptor signaling pathway; GO:0050778 positive regulation of immune response; GO:0023014 signal transduction by protein phosphorylation; GO:0006950 response to stress; GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; GO:0016567 protein ubiquitination; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress; GO:0006974 cellular response to DNA damage stimulus; GO:0031398 positive regulation of protein ubiquitination; GO:0032446 protein modification by small protein conjugation; GO:0007289 spermatid nucleus differentiation; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0030177 positive regulation of Wnt signaling pathway; GO:0048515 spermatid differentiation; GO:1904668 positive regulation of ubiquitin protein ligase activity; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0043412 macromolecule modification; GO:0070646 protein modification by small protein removal; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0048869 cellular developmental process; GO:0031331 positive regulation of cellular catabolic process; GO:0044699 single-organism process; GO:0006796 phosphate-containing compound metabolic process; GO:0031396 regulation of protein ubiquitination; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0045930 negative regulation of mitotic cell cycle; GO:0009893 positive regulation of metabolic process; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0034612 response to tumor necrosis factor; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0051726 regulation of cell cycle; GO:0071824 protein-DNA complex subunit organization; GO:0034097 response to cytokine; GO:0031326 regulation of cellular biosynthetic process; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0198738 cell-cell signaling by wnt; GO:0010565 regulation of cellular ketone metabolic process; GO:0065009 regulation of molecular function; GO:0035093 spermatogenesis, exchange of chromosomal proteins; GO:0006325 chromatin organization; GO:0036211 protein modification process; GO:0016043 cellular component organization; GO:0090175 regulation of establishment of planar polarity; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0045786 negative regulation of cell cycle; GO:0044257 cellular protein catabolic process; GO:1901988 negative regulation of cell cycle phase transition; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0035092 sperm chromatin condensation; GO:0010498 proteasomal protein catabolic process; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0045862 positive regulation of proteolysis; GO:2000027 regulation of organ morphogenesis; GO:0006468 protein phosphorylation; GO:0023056 positive regulation of signaling; GO:0001666 response to hypoxia; GO:0002757 immune response-activating signal transduction; GO:0034641 cellular nitrogen compound metabolic process; GO:0010647 positive regulation of cell communication; GO:0071453 cellular response to oxygen levels; GO:0019221 cytokine-mediated signaling pathway; GO:0006355 regulation of transcription, DNA-templated; GO:0048232 male gamete generation; GO:0035556 intracellular signal transduction; GO:0019941 modification-dependent protein catabolic process; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia; GO:1902749 regulation of cell cycle G2/M phase transition; GO:0043488 regulation of mRNA stability; GO:0043933 macromolecular complex subunit organization; GO:0043085 positive regulation of catalytic activity; GO:0019882 antigen processing and presentation; GO:0006281 DNA repair; GO:0050852 T cell receptor signaling pathway; GO:0002684 positive regulation of immune system process; GO:0044703 multi-organism reproductive process; GO:0038095 Fc-epsilon receptor signaling pathway; GO:1902750 negative regulation of cell cycle G2/M phase transition; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0002220 innate immune response activating cell surface receptor signaling pathway; GO:0007166 cell surface receptor signaling pathway; GO:0071345 cellular response to cytokine stimulus; GO:0044702 single organism reproductive process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0051347 positive regulation of transferase activity; GO:1903362 regulation of cellular protein catabolic process; GO:0003006 developmental process involved in reproduction; GO:0002758 innate immune response-activating signal transduction; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0019953 sexual reproduction; GO:0043044 ATP-dependent chromatin remodeling; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:2000058 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0010948 negative regulation of cell cycle process; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0002682 regulation of immune system process; GO:0031145 anaphase-promoting complex-dependent catabolic process; GO:0010952 positive regulation of peptidase activity; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0007346 regulation of mitotic cell cycle; GO:0006338 chromatin remodeling; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:0051239 regulation of multicellular organismal process; GO:0006323 DNA packaging; GO:0031349 positive regulation of defense response; GO:1901987 regulation of cell cycle phase transition; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0010389 regulation of G2/M transition of mitotic cell cycle; GO:0007275 multicellular organism development; GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; GO:0009966 regulation of signal transduction; GO:0038061 NIK/NF-kappaB signaling; GO:0071456 cellular response to hypoxia; GO:0002253 activation of immune response; GO:0007283 spermatogenesis; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:1904666 regulation of ubiquitin protein ligase activity; GO:0055085 transmembrane transport; GO:0051247 positive regulation of protein metabolic process; GO:0051276 chromosome organization; GO:0051438 regulation of ubiquitin-protein transferase activity; GO:0030111 regulation of Wnt signaling pathway; GO:0006793 phosphorus metabolic process; GO:0036293 response to decreased oxygen levels; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process; GO:0090090 negative regulation of canonical Wnt signaling pathway; GO:0051234 establishment of localization; GO:0035567 non-canonical Wnt signaling pathway; GO:1905330 regulation of morphogenesis of an epithelium; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:1901991 negative regulation of mitotic cell cycle phase transition; GO:0045088 regulation of innate immune response; GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I; GO:0070887 cellular response to chemical stimulus; GO:0071103 DNA conformation change; GO:0050851 antigen receptor-mediated signaling pathway; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0030178 negative regulation of Wnt signaling pathway; GO:0048002 antigen processing and presentation of peptide antigen; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0042221 response to chemical; GO:0090304 nucleic acid metabolic process; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0022412 cellular process involved in reproduction in multicellular organism; GO:0019222 regulation of metabolic process; GO:0052547 regulation of peptidase activity; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0006997 nucleus organization; GO:0002218 activation of innate immune response; GO:0006725 cellular aromatic compound metabolic process; GO:0071356 cellular response to tumor necrosis factor; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0050896 response to stimulus; GO:0016579 protein deubiquitination; GO:0048468 cell development; GO:1903322 positive regulation of protein modification by small protein conjugation or removal; GO:0007281 germ cell development; GO:0006508 proteolysis; GO:0009987 cellular process; GO:0033238 regulation of cellular amine metabolic process; GO:0043632 modification-dependent macromolecule catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0045089 positive regulation of innate immune response; GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition; GO:0031401 positive regulation of protein modification process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0007276 gamete generation; GO:0032504 multicellular organism reproduction; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0009057 macromolecule catabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0009967 positive regulation of signal transduction; GO:0045732 positive regulation of protein catabolic process; GO:0036294 cellular response to decreased oxygen levels; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0000502 proteasome complex; GO:1990111 spermatoproteasome complex; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:1905369 endopeptidase complex; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0005622 intracellular; GO:0044464 cell part; GO:0005839 proteasome core complex; GO:1905368 peptidase complex; GO:0043227 membrane-bounded organelle; GO:0043234 protein complex; GO:0044451 nucleoplasm part; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0042393 histone binding; GO:0030234 enzyme regulator activity; GO:0070577 lysine-acetylated histone binding; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0061134 peptidase regulator activity; GO:0016504 peptidase activator activity; GO:0005515 protein binding; GO:0070628 proteasome binding; GO:0098772 molecular function regulator; GO:0008047 enzyme activator activity; GO:0032403 protein complex binding; ","K06699","PSME4; proteasome activator subunit 4","hsa03050 Proteasome - Homo sapiens (human); ","IPR032430; IPR011989; IPR016024; ","\"Proteasome activator Blm10, mid region; Armadillo-like helical; Armadillo-type fold; \"\r"]
["Q14BN4","Sarcolemmal membrane-associated protein OS=Homo sapiens OX=9606 GN=SLMAP","SLMAP",95.197,24.633,15.2,13,14,13,1.074,1.104,1.077,0.874,0.934,0.927,0.84,1.56E-3,"peroxisome\r","GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0065008 regulation of biological quality; GO:0002028 regulation of sodium ion transport; GO:0003012 muscle system process; GO:0010256 endomembrane system organization; GO:2000021 regulation of ion homeostasis; GO:0044699 single-organism process; GO:0003254 regulation of membrane depolarization; GO:0032844 regulation of homeostatic process; GO:1990778 protein localization to cell periphery; GO:0098901 regulation of cardiac muscle cell action potential; GO:0098900 regulation of action potential; GO:0006936 muscle contraction; GO:1902578 single-organism localization; GO:0032879 regulation of localization; GO:0010959 regulation of metal ion transport; GO:1902580 single-organism cellular localization; GO:0034613 cellular protein localization; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0009987 cellular process; GO:0032409 regulation of transporter activity; GO:1904062 regulation of cation transmembrane transport; GO:0098902 regulation of membrane depolarization during action potential; GO:0003008 system process; GO:0072657 protein localization to membrane; GO:0051049 regulation of transport; GO:1905150 regulation of voltage-gated sodium channel activity; GO:0044763 single-organism cellular process; GO:0043269 regulation of ion transport; GO:0044802 single-organism membrane organization; GO:2000649 regulation of sodium ion transmembrane transporter activity; GO:0022898 regulation of transmembrane transporter activity; GO:0007009 plasma membrane organization; GO:0032501 multicellular organismal process; GO:0042391 regulation of membrane potential; GO:0051641 cellular localization; GO:0034762 regulation of transmembrane transport; GO:0070727 cellular macromolecule localization; GO:0072659 protein localization to plasma membrane; GO:0050789 regulation of biological process; GO:0034765 regulation of ion transmembrane transport; GO:0061024 membrane organization; GO:2001257 regulation of cation channel activity; GO:0065009 regulation of molecular function; GO:1902305 regulation of sodium ion transmembrane transport; GO:0032412 regulation of ion transmembrane transporter activity; GO:0051179 localization; GO:1900825 regulation of membrane depolarization during cardiac muscle cell action potential; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0005790 smooth endoplasmic reticulum; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0031226 intrinsic component of plasma membrane; GO:0005783 endoplasmic reticulum; GO:0043232 intracellular non-membrane-bounded organelle; GO:0071944 cell periphery; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0005886 plasma membrane; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0005856 cytoskeleton; GO:0043231 intracellular membrane-bounded organelle; GO:0005815 microtubule organizing center; GO:0044459 plasma membrane part; GO:0015630 microtubule cytoskeleton; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0042383 sarcolemma; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR008984; IPR000253; ","SMAD/FHA domain; Forkhead-associated (FHA) domain; \r"]
["Q15008","26S proteasome non-ATPase regulatory subunit 6 OS=Homo sapiens OX=9606 GN=PSMD6","PSMD6",45.531,53.702,31.9,12,16,12,0.948,0.998,0.926,1.069,1.068,1.126,1.136,0.0105,"cytoplasm\r","GO:0044700 single organism signaling; GO:0010608 posttranscriptional regulation of gene expression; GO:0051443 positive regulation of ubiquitin-protein transferase activity; GO:0031347 regulation of defense response; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:1903364 positive regulation of cellular protein catabolic process; GO:0008152 metabolic process; GO:0044093 positive regulation of molecular function; GO:0090263 positive regulation of canonical Wnt signaling pathway; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0016055 Wnt signaling pathway; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0006521 regulation of cellular amino acid metabolic process; GO:0080090 regulation of primary metabolic process; GO:0010972 negative regulation of G2/M transition of mitotic cell cycle; GO:0044763 single-organism cellular process; GO:0060828 regulation of canonical Wnt signaling pathway; GO:0043086 negative regulation of catalytic activity; GO:0033209 tumor necrosis factor-mediated signaling pathway; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0000165 MAPK cascade; GO:1901575 organic substance catabolic process; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0007267 cell-cell signaling; GO:0002223 stimulatory C-type lectin receptor signaling pathway; GO:0030163 protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0060071 Wnt signaling pathway, planar cell polarity pathway; GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0016310 phosphorylation; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0043487 regulation of RNA stability; GO:0000209 protein polyubiquitination; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0009889 regulation of biosynthetic process; GO:0009896 positive regulation of catabolic process; GO:0043620 regulation of DNA-templated transcription in response to stress; GO:0070482 response to oxygen levels; GO:0044248 cellular catabolic process; GO:0042176 regulation of protein catabolic process; GO:0038093 Fc receptor signaling pathway; GO:0050778 positive regulation of immune response; GO:0023014 signal transduction by protein phosphorylation; GO:0006950 response to stress; GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; GO:0016567 protein ubiquitination; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress; GO:0002263 cell activation involved in immune response; GO:1903321 negative regulation of protein modification by small protein conjugation or removal; GO:0045055 regulated exocytosis; GO:0031398 positive regulation of protein ubiquitination; GO:0032446 protein modification by small protein conjugation; GO:0031325 positive regulation of cellular metabolic process; GO:0030177 positive regulation of Wnt signaling pathway; GO:1904668 positive regulation of ubiquitin protein ligase activity; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0006955 immune response; GO:0043412 macromolecule modification; GO:0070646 protein modification by small protein removal; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0031331 positive regulation of cellular catabolic process; GO:0044699 single-organism process; GO:0031400 negative regulation of protein modification process; GO:0006796 phosphate-containing compound metabolic process; GO:0031396 regulation of protein ubiquitination; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0045930 negative regulation of mitotic cell cycle; GO:0009893 positive regulation of metabolic process; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0034612 response to tumor necrosis factor; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0051726 regulation of cell cycle; GO:0034097 response to cytokine; GO:0031326 regulation of cellular biosynthetic process; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0198738 cell-cell signaling by wnt; GO:0010565 regulation of cellular ketone metabolic process; GO:0032940 secretion by cell; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0036211 protein modification process; GO:0090175 regulation of establishment of planar polarity; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0045786 negative regulation of cell cycle; GO:0044257 cellular protein catabolic process; GO:1901988 negative regulation of cell cycle phase transition; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0010498 proteasomal protein catabolic process; GO:0071704 organic substance metabolic process; GO:0045862 positive regulation of proteolysis; GO:2000027 regulation of organ morphogenesis; GO:0006468 protein phosphorylation; GO:0023056 positive regulation of signaling; GO:0001666 response to hypoxia; GO:0002757 immune response-activating signal transduction; GO:0010647 positive regulation of cell communication; GO:0071453 cellular response to oxygen levels; GO:0019221 cytokine-mediated signaling pathway; GO:0031397 negative regulation of protein ubiquitination; GO:0006355 regulation of transcription, DNA-templated; GO:0035556 intracellular signal transduction; GO:0019941 modification-dependent protein catabolic process; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia; GO:1902749 regulation of cell cycle G2/M phase transition; GO:0043488 regulation of mRNA stability; GO:0043085 positive regulation of catalytic activity; GO:0002366 leukocyte activation involved in immune response; GO:0019882 antigen processing and presentation; GO:0042119 neutrophil activation; GO:0050852 T cell receptor signaling pathway; GO:0002684 positive regulation of immune system process; GO:0038095 Fc-epsilon receptor signaling pathway; GO:0051248 negative regulation of protein metabolic process; GO:0022402 cell cycle process; GO:1902750 negative regulation of cell cycle G2/M phase transition; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0045321 leukocyte activation; GO:0002220 innate immune response activating cell surface receptor signaling pathway; GO:0007166 cell surface receptor signaling pathway; GO:0071345 cellular response to cytokine stimulus; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0051347 positive regulation of transferase activity; GO:1903362 regulation of cellular protein catabolic process; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0002443 leukocyte mediated immunity; GO:0002758 innate immune response-activating signal transduction; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0031323 regulation of cellular metabolic process; GO:2000058 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0010948 negative regulation of cell cycle process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0002682 regulation of immune system process; GO:0031145 anaphase-promoting complex-dependent catabolic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0007346 regulation of mitotic cell cycle; GO:0002283 neutrophil activation involved in immune response; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:0051239 regulation of multicellular organismal process; GO:0031349 positive regulation of defense response; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:1901987 regulation of cell cycle phase transition; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0010389 regulation of G2/M transition of mitotic cell cycle; GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; GO:0009966 regulation of signal transduction; GO:0038061 NIK/NF-kappaB signaling; GO:0071456 cellular response to hypoxia; GO:0002253 activation of immune response; GO:0016192 vesicle-mediated transport; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1904666 regulation of ubiquitin protein ligase activity; GO:0055085 transmembrane transport; GO:0051247 positive regulation of protein metabolic process; GO:0051438 regulation of ubiquitin-protein transferase activity; GO:0030111 regulation of Wnt signaling pathway; GO:0006793 phosphorus metabolic process; GO:0001775 cell activation; GO:0036293 response to decreased oxygen levels; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process; GO:0006887 exocytosis; GO:0051444 negative regulation of ubiquitin-protein transferase activity; GO:0090090 negative regulation of canonical Wnt signaling pathway; GO:0051234 establishment of localization; GO:0035567 non-canonical Wnt signaling pathway; GO:1905330 regulation of morphogenesis of an epithelium; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:1901991 negative regulation of mitotic cell cycle phase transition; GO:0045088 regulation of innate immune response; GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I; GO:0070887 cellular response to chemical stimulus; GO:0002274 myeloid leukocyte activation; GO:0050851 antigen receptor-mediated signaling pathway; GO:0010468 regulation of gene expression; GO:0030178 negative regulation of Wnt signaling pathway; GO:0048002 antigen processing and presentation of peptide antigen; GO:0002446 neutrophil mediated immunity; GO:0048522 positive regulation of cellular process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0051348 negative regulation of transferase activity; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0019222 regulation of metabolic process; GO:0043299 leukocyte degranulation; GO:2000026 regulation of multicellular organismal development; GO:0002218 activation of innate immune response; GO:1904667 negative regulation of ubiquitin protein ligase activity; GO:0002252 immune effector process; GO:0071356 cellular response to tumor necrosis factor; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0016579 protein deubiquitination; GO:0050896 response to stimulus; GO:1903322 positive regulation of protein modification by small protein conjugation or removal; GO:0006508 proteolysis; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:0033238 regulation of cellular amine metabolic process; GO:0043632 modification-dependent macromolecule catabolic process; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0045089 positive regulation of innate immune response; GO:0031401 positive regulation of protein modification process; GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0051246 regulation of protein metabolic process; GO:0009057 macromolecule catabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0009967 positive regulation of signal transduction; GO:0045732 positive regulation of protein catabolic process; GO:0036294 cellular response to decreased oxygen levels; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005838 proteasome regulatory particle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:1905369 endopeptidase complex; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:1902494 catalytic complex; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0022624 proteasome accessory complex; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:1905368 peptidase complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0000502 proteasome complex; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017111 nucleoside-triphosphatase activity; GO:0016887 ATPase activity; ","K03037","PSMD6; 26S proteasome regulatory subunit N7","hsa03050 Proteasome - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); ","IPR000717; IPR011991; IPR011990; ","Proteasome component (PCI) domain; Winged helix-turn-helix DNA-binding domain; Tetratricopeptide-like helical domain; \r"]
["Q15018","BRISC complex subunit Abraxas 2 OS=Homo sapiens OX=9606 GN=ABRAXAS2","ABRAXAS2",46.9,3.8449,4.1,2,2,2,1.077,1.132,1.098,0.921,0.878,0.916,0.821,0.000704,"plasma membrane\r","GO:0044085 cellular component biogenesis; GO:0070646 protein modification by small protein removal; GO:0016043 cellular component organization; GO:0007067 mitotic nuclear division; GO:0048285 organelle fission; GO:0044267 cellular protein metabolic process; GO:0007051 spindle organization; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0016579 protein deubiquitination; GO:0044237 cellular metabolic process; GO:1903047 mitotic cell cycle process; GO:0070536 protein K63-linked deubiquitination; GO:0071704 organic substance metabolic process; GO:0002931 response to ischemia; GO:0008152 metabolic process; GO:0051225 spindle assembly; GO:0070925 organelle assembly; GO:0022607 cellular component assembly; GO:0008608 attachment of spindle microtubules to kinetochore; GO:0006508 proteolysis; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0007052 mitotic spindle organization; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0000278 mitotic cell cycle; GO:0007059 chromosome segregation; GO:0006950 response to stress; GO:0044763 single-organism cellular process; GO:0070647 protein modification by small protein conjugation or removal; GO:0044238 primary metabolic process; GO:0007017 microtubule-based process; GO:0000226 microtubule cytoskeleton organization; GO:0098813 nuclear chromosome segregation; GO:0006996 organelle organization; GO:0044260 cellular macromolecule metabolic process; GO:0000280 nuclear division; GO:1902850 microtubule cytoskeleton organization involved in mitosis; GO:0090307 mitotic spindle assembly; GO:0006464 cellular protein modification process; GO:0051301 cell division; GO:0022402 cell cycle process; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0000922 spindle pole; GO:0005874 microtubule; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0005819 spindle; GO:0044422 organelle part; GO:0070552 BRISC complex; GO:0099081 supramolecular polymer; GO:0043228 non-membrane-bounded organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005856 cytoskeleton; GO:0005634 nucleus; GO:0015630 microtubule cytoskeleton; GO:0044464 cell part; GO:0005622 intracellular; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0031593 polyubiquitin binding; GO:0008092 cytoskeletal protein binding; GO:0008017 microtubule binding; GO:0005488 binding; GO:0015631 tubulin binding; GO:0043130 ubiquitin binding; GO:0005515 protein binding; GO:0032182 ubiquitin-like protein binding; ","K20799"]
["Q15031","Probable leucine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=LARS2","LARS2",101.97,2.6973,2,2,3,2,1.312,1.162,1.213,0.75,0.773,0.826,0.637,0.000584,"mitochondria\r","GO:0065008 regulation of biological quality; GO:0006518 peptide metabolic process; GO:0010608 posttranscriptional regulation of gene expression; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0006418 tRNA aminoacylation for protein translation; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0006412 translation; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0043043 peptide biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0016070 RNA metabolic process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006429 leucyl-tRNA aminoacylation; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006082 organic acid metabolic process; GO:0043436 oxoacid metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0044267 cellular protein metabolic process; GO:0043039 tRNA aminoacylation; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006448 regulation of translational elongation; GO:0006450 regulation of translational fidelity; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0032543 mitochondrial translation; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0034248 regulation of cellular amide metabolic process; GO:0006399 tRNA metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0006417 regulation of translation; GO:0051246 regulation of protein metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0043038 amino acid activation; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0034660 ncRNA metabolic process; GO:0065007 biological regulation; GO:1901564 organonitrogen compound metabolic process; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds; GO:0002161 aminoacyl-tRNA editing activity; GO:0005524 ATP binding; GO:0052689 carboxylic ester hydrolase activity; GO:1901265 nucleoside phosphate binding; GO:0016875 ligase activity, forming carbon-oxygen bonds; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016874 ligase activity; GO:0016787 hydrolase activity; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0004823 leucine-tRNA ligase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0032550 purine ribonucleoside binding; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0004812 aminoacyl-tRNA ligase activity; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K01869","LARS; leucyl-tRNA synthetase [EC:6.1.1.4]","hsa00970 Aminoacyl-tRNA biosynthesis - Homo sapiens (human); ","IPR014729; IPR009008; IPR013155; IPR002300; IPR009080; ","\"Rossmann-like alpha/beta/alpha sandwich fold; Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain; Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding; Aminoacyl-tRNA synthetase, class Ia; Aminoacyl-tRNA synthetase, class Ia, anticodon-binding; \"\r"]
["Q15036","Sorting nexin-17 OS=Homo sapiens OX=9606 GN=SNX17","SNX17",52.901,12.663,9.6,3,4,3,1.012,0.998,1.342,1.001,0.99,0.676,0.796,0.219,"nucleus\r","GO:0044700 single organism signaling; GO:0060627 regulation of vesicle-mediated transport; GO:0001568 blood vessel development; GO:0006066 alcohol metabolic process; GO:0044699 single-organism process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0007507 heart development; GO:0007154 cell communication; GO:0032879 regulation of localization; GO:1901361 organic cyclic compound catabolic process; GO:1990126 retrograde transport, endosome to plasma membrane; GO:0006707 cholesterol catabolic process; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0006629 lipid metabolic process; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0044281 small molecule metabolic process; GO:0008202 steroid metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0001944 vasculature development; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0035904 aorta development; GO:0060976 coronary vasculature development; GO:0016197 endosomal transport; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0044710 single-organism metabolic process; GO:0060840 artery development; GO:0048856 anatomical structure development; GO:0050794 regulation of cellular process; GO:0072359 circulatory system development; GO:0044707 single-multicellular organism process; GO:0046907 intracellular transport; GO:1901615 organic hydroxy compound metabolic process; GO:1902652 secondary alcohol metabolic process; GO:0046164 alcohol catabolic process; GO:0050896 response to stimulus; GO:0016125 sterol metabolic process; GO:0071704 organic substance metabolic process; GO:1901616 organic hydroxy compound catabolic process; GO:0006886 intracellular protein transport; GO:0016127 sterol catabolic process; GO:0006898 receptor-mediated endocytosis; GO:0007275 multicellular organism development; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0016042 lipid catabolic process; GO:0008203 cholesterol metabolic process; GO:0030100 regulation of endocytosis; GO:0098876 vesicle-mediated transport to the plasma membrane; GO:0003279 cardiac septum development; GO:0048731 system development; GO:0051049 regulation of transport; GO:0044712 single-organism catabolic process; GO:0016192 vesicle-mediated transport; GO:0071702 organic substance transport; GO:0072358 cardiovascular system development; GO:0044282 small molecule catabolic process; GO:0006897 endocytosis; GO:0044238 primary metabolic process; GO:0003205 cardiac chamber development; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0044767 single-organism developmental process; GO:0006706 steroid catabolic process; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0009056 catabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0010008 endosome membrane; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0012506 vesicle membrane; GO:0005829 cytosol; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043234 protein complex; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:0070325 lipoprotein particle receptor binding; GO:0005102 receptor binding; GO:0005488 binding; GO:0035091 phosphatidylinositol binding; GO:0005543 phospholipid binding; GO:0043167 ion binding; GO:0008289 lipid binding; GO:0008022 protein C-terminus binding; GO:0005515 protein binding; GO:0043168 anion binding; GO:0050750 low-density lipoprotein particle receptor binding; ","K17929",null,null,"IPR001683; IPR000159; ","Phox homologous domain; Ras-associating (RA) domain; \r"]
["Q15043","Zinc transporter ZIP14 OS=Homo sapiens OX=9606 GN=SLC39A14","SLC39A14",54.212,3.9205,4.3,2,2,2,0.872,0.843,0.89,1.034,1.086,1.26,1.298,0.0139,"plasma membrane\r","GO:0034755 iron ion transmembrane transport; GO:0071421 manganese ion transmembrane transport; GO:0065008 regulation of biological quality; GO:0055076 transition metal ion homeostasis; GO:0072503 cellular divalent inorganic cation homeostasis; GO:0072511 divalent inorganic cation transport; GO:0034220 ion transmembrane transport; GO:0030001 metal ion transport; GO:0030003 cellular cation homeostasis; GO:0044699 single-organism process; GO:0006826 iron ion transport; GO:0006828 manganese ion transport; GO:0055082 cellular chemical homeostasis; GO:0055069 zinc ion homeostasis; GO:0051234 establishment of localization; GO:0042592 homeostatic process; GO:0000041 transition metal ion transport; GO:0055080 cation homeostasis; GO:0006812 cation transport; GO:0071578 zinc II ion transmembrane import; GO:0055065 metal ion homeostasis; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0015684 ferrous iron transport; GO:0098655 cation transmembrane transport; GO:0050801 ion homeostasis; GO:0098660 inorganic ion transmembrane transport; GO:0006829 zinc II ion transport; GO:0098771 inorganic ion homeostasis; GO:0044763 single-organism cellular process; GO:0019725 cellular homeostasis; GO:0046916 cellular transition metal ion homeostasis; GO:0071577 zinc II ion transmembrane transport; GO:0006810 transport; GO:0055085 transmembrane transport; GO:0006882 cellular zinc ion homeostasis; GO:0006873 cellular ion homeostasis; GO:0006811 ion transport; GO:1903874 ferrous iron transmembrane transport; GO:0006875 cellular metal ion homeostasis; GO:0051179 localization; GO:0072507 divalent inorganic cation homeostasis; GO:0098662 inorganic cation transmembrane transport; GO:0065007 biological regulation; GO:0070838 divalent metal ion transport; ","GO:0031252 cell leading edge; GO:0016020 membrane; GO:0031226 intrinsic component of plasma membrane; GO:0042995 cell projection; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0044459 plasma membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0044425 membrane part; GO:0030027 lamellipodium; ","GO:0005384 manganese ion transmembrane transporter activity; GO:0046873 metal ion transmembrane transporter activity; GO:0072509 divalent inorganic cation transmembrane transporter activity; GO:0015075 ion transmembrane transporter activity; GO:0005385 zinc ion transmembrane transporter activity; GO:0005381 iron ion transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0046915 transition metal ion transmembrane transporter activity; GO:0015093 ferrous iron transmembrane transporter activity; GO:0022890 inorganic cation transmembrane transporter activity; GO:0008324 cation transmembrane transporter activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; ","K14720","SLC39A14; solute carrier family 39 (zinc transporter), member 14","hsa04216 Ferroptosis - Homo sapiens (human); "]
["Q15046","Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS","KARS",68.047,43.524,20.1,12,22,12,0.87,0.89,0.876,1.107,1.118,1.11,1.265,2.84e-06,"cytoplasm\r","GO:0006518 peptide metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0015966 diadenosine tetraphosphate biosynthetic process; GO:0006418 tRNA aminoacylation for protein translation; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0006412 translation; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0006430 lysyl-tRNA aminoacylation; GO:0018130 heterocycle biosynthetic process; GO:0015965 diadenosine tetraphosphate metabolic process; GO:0043043 peptide biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0043603 cellular amide metabolic process; GO:0051704 multi-organism process; GO:0090407 organophosphate biosynthetic process; GO:0016070 RNA metabolic process; GO:0090304 nucleic acid metabolic process; GO:0044710 single-organism metabolic process; GO:0015960 diadenosine polyphosphate biosynthetic process; GO:0008033 tRNA processing; GO:0044260 cellular macromolecule metabolic process; GO:0006082 organic acid metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0015959 diadenosine polyphosphate metabolic process; GO:0043436 oxoacid metabolic process; GO:0009165 nucleotide biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0043039 tRNA aminoacylation; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0016032 viral process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0044711 single-organism biosynthetic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0006399 tRNA metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0043038 amino acid activation; GO:0019637 organophosphate metabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0034660 ncRNA metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044429 mitochondrial part; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0005886 plasma membrane; GO:0017101 aminoacyl-tRNA synthetase multienzyme complex; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds; GO:0016597 amino acid binding; GO:1901265 nucleoside phosphate binding; GO:0016875 ligase activity, forming carbon-oxygen bonds; GO:0016874 ligase activity; GO:0005515 protein binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0031406 carboxylic acid binding; GO:0000049 tRNA binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0004812 aminoacyl-tRNA ligase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003723 RNA binding; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0043177 organic acid binding; GO:0000166 nucleotide binding; GO:0004824 lysine-tRNA ligase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003676 nucleic acid binding; GO:0046872 metal ion binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; ","K04567","KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]","hsa00970 Aminoacyl-tRNA biosynthesis - Homo sapiens (human); ","IPR004364; IPR012340; IPR004365; IPR018149; IPR006195; ","\"Aminoacyl-tRNA synthetase, class II (D/K/N); Nucleic acid-binding, OB-fold; OB-fold nucleic acid binding domain, AA-tRNA synthetase-type; Lysyl-tRNA synthetase, class II, C-terminal; Aminoacyl-tRNA synthetase, class II; \"\r"]
["Q15067","Peroxisomal acyl-coenzyme A oxidase 1 OS=Homo sapiens OX=9606 GN=ACOX1","ACOX1",74.423,99.558,20.3,10,12,10,0.947,0.863,0.977,1.12,0.974,1.089,1.142,0.0795,"cytoplasm\r","GO:0065008 regulation of biological quality; GO:0022414 reproductive process; GO:1901568 fatty acid derivative metabolic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0030258 lipid modification; GO:0032846 positive regulation of homeostatic process; GO:0044702 single organism reproductive process; GO:0032787 monocarboxylic acid metabolic process; GO:0055088 lipid homeostasis; GO:0006690 icosanoid metabolic process; GO:0016559 peroxisome fission; GO:0006629 lipid metabolic process; GO:0019395 fatty acid oxidation; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0019953 sexual reproduction; GO:0044763 single-organism cellular process; GO:0072329 monocarboxylic acid catabolic process; GO:2000189 positive regulation of cholesterol homeostasis; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0046395 carboxylic acid catabolic process; GO:1901575 organic substance catabolic process; GO:0050789 regulation of biological process; GO:0044710 single-organism metabolic process; GO:0006693 prostaglandin metabolic process; GO:0006082 organic acid metabolic process; GO:0048609 multicellular organismal reproductive process; GO:0009062 fatty acid catabolic process; GO:0043436 oxoacid metabolic process; GO:0033559 unsaturated fatty acid metabolic process; GO:0000003 reproduction; GO:0034440 lipid oxidation; GO:0016043 cellular component organization; GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase; GO:0048285 organelle fission; GO:0036109 alpha-linolenic acid metabolic process; GO:0032844 regulation of homeostatic process; GO:0071704 organic substance metabolic process; GO:0007031 peroxisome organization; GO:0042592 homeostatic process; GO:0044248 cellular catabolic process; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:2000188 regulation of cholesterol homeostasis; GO:0016042 lipid catabolic process; GO:0048232 male gamete generation; GO:0044712 single-organism catabolic process; GO:0007283 spermatogenesis; GO:0006692 prostanoid metabolic process; GO:0006635 fatty acid beta-oxidation; GO:0044282 small molecule catabolic process; GO:0006631 fatty acid metabolic process; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0007276 gamete generation; GO:0032504 multicellular organism reproduction; GO:0000038 very long-chain fatty acid metabolic process; GO:0001676 long-chain fatty acid metabolic process; GO:0006996 organelle organization; GO:0044703 multi-organism reproductive process; GO:0016054 organic acid catabolic process; GO:0019752 carboxylic acid metabolic process; GO:0044242 cellular lipid catabolic process; GO:0009056 catabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0044438 microbody part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005778 peroxisomal membrane; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005782 peroxisomal matrix; GO:0005622 intracellular; GO:0044464 cell part; GO:0042579 microbody; GO:0098805 whole membrane; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0031903 microbody membrane; GO:0044439 peroxisomal part; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005777 peroxisome; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0031907 microbody lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor; GO:1901265 nucleoside phosphate binding; GO:0047485 protein N-terminus binding; GO:0050660 flavin adenine dinucleotide binding; GO:0005102 receptor binding; GO:0043167 ion binding; GO:0003997 acyl-CoA oxidase activity; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0016401 palmitoyl-CoA oxidase activity; GO:0030165 PDZ domain binding; GO:0048037 cofactor binding; GO:0071949 FAD binding; GO:0016491 oxidoreductase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors; GO:0003824 catalytic activity; GO:0005488 binding; GO:0019904 protein domain specific binding; GO:0043168 anion binding; GO:0003995 acyl-CoA dehydrogenase activity; GO:0050662 coenzyme binding; GO:0036094 small molecule binding; ","K00232","E1.3.3.6; acyl-CoA oxidase [EC:1.3.3.6]","hsa03320 PPAR signaling pathway - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa01212 Fatty acid metabolism - Homo sapiens (human); hsa00592 alpha-Linolenic acid metabolism - Homo sapiens (human); hsa04146 Peroxisome - Homo sapiens (human); hsa04024 cAMP signaling pathway - Homo sapiens (human); hsa00071 Fatty acid degradation - Homo sapiens (human); hsa01040 Biosynthesis of unsaturated fatty acids - Homo sapiens (human); ","IPR029320; IPR009100; IPR013786; IPR006091; IPR002655; IPR009075; ","\"Acyl-coenzyme A oxidase, N-terminal; Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain; Acyl-CoA dehydrogenase/oxidase, N-terminal; Acyl-CoA oxidase/dehydrogenase, central domain; Acyl-CoA oxidase, C-terminal; Acyl-CoA dehydrogenase/oxidase C-terminal; \"\r"]
["Q15075","Early endosome antigen 1 OS=Homo sapiens OX=9606 GN=EEA1","EEA1",162.46,323.31,42.6,55,73,55,1.02,1.047,1.02,0.956,0.972,0.955,0.934,2.8E-3,"nucleus\r","GO:0090174 organelle membrane fusion; GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0019079 viral genome replication; GO:0006725 cellular aromatic compound metabolic process; GO:0019058 viral life cycle; GO:0016189 synaptic vesicle to endosome fusion; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0099532 synaptic vesicle endosomal processing; GO:0099504 synaptic vesicle cycle; GO:0071704 organic substance metabolic process; GO:0051234 establishment of localization; GO:0098927 vesicle-mediated transport between endosomal compartments; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0051649 establishment of localization in cell; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0016032 viral process; GO:0039703 RNA replication; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0044801 single-organism membrane fusion; GO:0016482 cytosolic transport; GO:0009987 cellular process; GO:0045022 early endosome to late endosome transport; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0061025 membrane fusion; GO:0016050 vesicle organization; GO:0044802 single-organism membrane organization; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0048284 organelle fusion; GO:0044238 primary metabolic process; GO:0006897 endocytosis; GO:0051704 multi-organism process; GO:0051641 cellular localization; GO:0016070 RNA metabolic process; GO:0006810 transport; GO:0016197 endosomal transport; GO:1902589 single-organism organelle organization; GO:0090304 nucleic acid metabolic process; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0044260 cellular macromolecule metabolic process; GO:0006906 vesicle fusion; GO:0039694 viral RNA genome replication; GO:0051179 localization; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0019898 extrinsic component of membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0055037 recycling endosome; GO:0070062 extracellular exosome; GO:1902494 catalytic complex; GO:0044309 neuron spine; GO:0098793 presynapse; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0005768 endosome; GO:0031901 early endosome membrane; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0044456 synapse part; GO:0010008 endosome membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0042995 cell projection; GO:0044308 axonal spine; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0019897 extrinsic component of plasma membrane; GO:0044440 endosomal part; GO:0012505 endomembrane system; GO:1990234 transferase complex; GO:0044463 cell projection part; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0033267 axon part; GO:0045202 synapse; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0030424 axon; GO:0005969 serine-pyruvate aminotransferase complex; GO:0044459 plasma membrane part; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005545 1-phosphatidylinositol binding; GO:0030742 GTP-dependent protein binding; GO:0046983 protein dimerization activity; GO:0043167 ion binding; GO:0005515 protein binding; GO:0008270 zinc ion binding; GO:0005516 calmodulin binding; GO:0042802 identical protein binding; GO:0046914 transition metal ion binding; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0035091 phosphatidylinositol binding; GO:0005543 phospholipid binding; GO:0008289 lipid binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0043168 anion binding; ","K12478","EEA1; early endosome antigen 1","hsa05152 Tuberculosis - Homo sapiens (human); hsa04144 Endocytosis - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); ","IPR000306; IPR017455; IPR013083; IPR011011; IPR007087; ","\"FYVE zinc finger; Zinc finger, FYVE-related; Zinc finger, RING/FYVE/PHD-type; Zinc finger, FYVE/PHD-type; Zinc finger, C2H2; \"\r"]
["Q15084","Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6","PDIA6",48.121,159.76,29.5,12,24,12,0.987,0.998,0.985,1.021,1,1.065,1.039,0.116,"extracellular\r","GO:0044700 single organism signaling; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0065008 regulation of biological quality; GO:0035967 cellular response to topologically incorrect protein; GO:0034976 response to endoplasmic reticulum stress; GO:0071310 cellular response to organic substance; GO:0045454 cell redox homeostasis; GO:0044699 single-organism process; GO:0036498 IRE1-mediated unfolded protein response; GO:0050896 response to stimulus; GO:0030968 endoplasmic reticulum unfolded protein response; GO:0006909 phagocytosis; GO:0051234 establishment of localization; GO:0006457 protein folding; GO:0042592 homeostatic process; GO:0007165 signal transduction; GO:0035966 response to topologically incorrect protein; GO:1902578 single-organism localization; GO:0007154 cell communication; GO:0043277 apoptotic cell clearance; GO:0009987 cellular process; GO:0070887 cellular response to chemical stimulus; GO:0044765 single-organism transport; GO:0051716 cellular response to stimulus; GO:0006986 response to unfolded protein; GO:0006950 response to stress; GO:0034620 cellular response to unfolded protein; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0019725 cellular homeostasis; GO:0010033 response to organic substance; GO:0006897 endocytosis; GO:0023052 signaling; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0051179 localization; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0048770 pigment granule; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005788 endoplasmic reticulum lumen; GO:0097708 intracellular vesicle; GO:0042470 melanosome; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0034663 endoplasmic reticulum chaperone complex; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044432 endoplasmic reticulum part; GO:0005793 endoplasmic reticulum-Golgi intermediate compartment; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds; GO:0005515 protein binding; GO:0016853 isomerase activity; GO:0016860 intramolecular oxidoreductase activity; GO:0003756 protein disulfide isomerase activity; GO:0003824 catalytic activity; GO:0005488 binding; ","K09584","PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]","hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); ","IPR005788; IPR012336; IPR013766; ","Disulphide isomerase; Thioredoxin-like fold; Thioredoxin domain; \r"]
["Q15121","Astrocytic phosphoprotein PEA-15 OS=Homo sapiens OX=9606 GN=PEA15","PEA15",15.04,72.679,53.1,7,11,7,1.012,1.08,1.053,0.962,0.948,0.912,0.897,0.0119,"cytoplasm\r","GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0032270 positive regulation of cellular protein metabolic process; GO:0044237 cellular metabolic process; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0008152 metabolic process; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0014072 response to isoquinoline alkaloid; GO:0009719 response to endogenous stimulus; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0051347 positive regulation of transferase activity; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0046324 regulation of glucose import; GO:0044765 single-organism transport; GO:0051051 negative regulation of transport; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0014070 response to organic cyclic compound; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:0060359 response to ammonium ion; GO:0044763 single-organism cellular process; GO:0031323 regulation of cellular metabolic process; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0006810 transport; GO:0000165 MAPK cascade; GO:0010243 response to organonitrogen compound; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:1901698 response to nitrogen compound; GO:0010604 positive regulation of macromolecule metabolic process; GO:0010829 negative regulation of glucose transport; GO:0006464 cellular protein modification process; GO:0060548 negative regulation of cell death; GO:0043068 positive regulation of programmed cell death; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0016310 phosphorylation; GO:0031399 regulation of protein modification process; GO:0043067 regulation of programmed cell death; GO:0044267 cellular protein metabolic process; GO:0043279 response to alkaloid; GO:0071902 positive regulation of protein serine/threonine kinase activity; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0023057 negative regulation of signaling; GO:1902578 single-organism localization; GO:0032147 activation of protein kinase activity; GO:0010648 negative regulation of cell communication; GO:0051338 regulation of transferase activity; GO:0009966 regulation of signal transduction; GO:0023014 signal transduction by protein phosphorylation; GO:1902531 regulation of intracellular signal transduction; GO:0006950 response to stress; GO:0071702 organic substance transport; GO:2001237 negative regulation of extrinsic apoptotic signaling pathway; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; GO:0006974 cellular response to DNA damage stimulus; GO:0051247 positive regulation of protein metabolic process; GO:0043406 positive regulation of MAP kinase activity; GO:0006793 phosphorus metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0012501 programmed cell death; GO:0048584 positive regulation of response to stimulus; GO:0043412 macromolecule modification; GO:0051179 localization; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:2001238 positive regulation of extrinsic apoptotic signaling pathway; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:2001233 regulation of apoptotic signaling pathway; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0000077 DNA damage checkpoint; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0006915 apoptotic process; GO:0000075 cell cycle checkpoint; GO:0033674 positive regulation of kinase activity; GO:0010827 regulation of glucose transport; GO:0051726 regulation of cell cycle; GO:0045937 positive regulation of phosphate metabolic process; GO:0043278 response to morphine; GO:0031570 DNA integrity checkpoint; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0010942 positive regulation of cell death; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:2001236 regulation of extrinsic apoptotic signaling pathway; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0036211 protein modification process; GO:0043549 regulation of kinase activity; GO:0045859 regulation of protein kinase activity; GO:0045786 negative regulation of cell cycle; GO:0043069 negative regulation of programmed cell death; GO:0043405 regulation of MAP kinase activity; GO:0060255 regulation of macromolecule metabolic process; GO:0043065 positive regulation of apoptotic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0006468 protein phosphorylation; GO:0043066 negative regulation of apoptotic process; GO:0043408 regulation of MAPK cascade; GO:0023056 positive regulation of signaling; GO:2001235 positive regulation of apoptotic signaling pathway; GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors; GO:0008643 carbohydrate transport; GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:0035556 intracellular signal transduction; GO:0051049 regulation of transport; GO:0001932 regulation of protein phosphorylation; GO:0031401 positive regulation of protein modification process; GO:0048585 negative regulation of response to stimulus; GO:0001934 positive regulation of protein phosphorylation; GO:0045860 positive regulation of protein kinase activity; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0000187 activation of MAPK activity; GO:0046325 negative regulation of glucose import; GO:0008219 cell death; GO:0051246 regulation of protein metabolic process; GO:0009967 positive regulation of signal transduction; GO:0043410 positive regulation of MAPK cascade; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005875 microtubule associated complex; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005856 cytoskeleton; GO:0005634 nucleus; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR001875; IPR011029; ","Death effector domain; Death-like domain; \r"]
["Q15147","1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 OS=Homo sapiens OX=9606 GN=PLCB4","PLCB4",134.46,2.435,1,1,1,1,1.167,1.374,1.104,0.751,0.732,0.911,0.657,0.0115,"nucleus\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0051716 cellular response to stimulus; GO:0016042 lipid catabolic process; GO:1901615 organic hydroxy compound metabolic process; GO:0035556 intracellular signal transduction; GO:0006066 alcohol metabolic process; GO:0044712 single-organism catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0023052 signaling; GO:0050896 response to stimulus; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0019751 polyol metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:1901575 organic substance catabolic process; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0050789 regulation of biological process; GO:0007154 cell communication; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0019637 organophosphate metabolic process; GO:0043647 inositol phosphate metabolic process; GO:0009987 cellular process; GO:0009056 catabolic process; GO:0065007 biological regulation; GO:0006629 lipid metabolic process; ","GO:0005790 smooth endoplasmic reticulum; GO:0043229 intracellular organelle; GO:0030425 dendrite; GO:0005783 endoplasmic reticulum; GO:0042995 cell projection; GO:0005737 cytoplasm; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0032279 asymmetric synapse; GO:0045202 synapse; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0036477 somatodendritic compartment; GO:0098794 postsynapse; GO:0044464 cell part; GO:0005622 intracellular; GO:0014069 postsynaptic density; GO:0043005 neuron projection; GO:0099572 postsynaptic specialization; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0098984 neuron to neuron synapse; GO:0044456 synapse part; GO:0044444 cytoplasmic part; ","GO:0004629 phospholipase C activity; GO:0043167 ion binding; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0016298 lipase activity; GO:0004871 signal transducer activity; GO:0004435 phosphatidylinositol phospholipase C activity; GO:0042578 phosphoric ester hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0004620 phospholipase activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0008081 phosphoric diester hydrolase activity; GO:0005509 calcium ion binding; ","K05858","PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]","hsa04072 Phospholipase D signaling pathway - Homo sapiens (human); hsa04015 Rap1 signaling pathway - Homo sapiens (human); hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human); hsa04924 Renin secretion - Homo sapiens (human); hsa04911 Insulin secretion - Homo sapiens (human); hsa04970 Salivary secretion - Homo sapiens (human); hsa04724 Glutamatergic synapse - Homo sapiens (human); hsa00562 Inositol phosphate metabolism - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa04934 Cushing's syndrome - Homo sapiens (human); hsa04071 Sphingolipid signaling pathway - Homo sapiens (human); hsa04070 Phosphatidylinositol signaling system - Homo sapiens (human); hsa04933 AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human); hsa04922 Glucagon signaling pathway - Homo sapiens (human); hsa04611 Platelet activation - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04927 Cortisol synthesis and secretion - Homo sapiens (human); hsa04971 Gastric acid secretion - Homo sapiens (human); hsa04915 Estrogen signaling pathway - Homo sapiens (human); hsa05143 African trypanosomiasis - Homo sapiens (human); hsa04725 Cholinergic synapse - Homo sapiens (human); hsa04310 Wnt signaling pathway - Homo sapiens (human); hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04921 Oxytocin signaling pathway - Homo sapiens (human); hsa05142 Chagas disease (American trypanosomiasis) - Homo sapiens (human); hsa04728 Dopaminergic synapse - Homo sapiens (human); hsa04371 Apelin signaling pathway - Homo sapiens (human); hsa04973 Carbohydrate digestion and absorption - Homo sapiens (human); hsa04916 Melanogenesis - Homo sapiens (human); hsa04020 Calcium signaling pathway - Homo sapiens (human); hsa04270 Vascular smooth muscle contraction - Homo sapiens (human); hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human); hsa04726 Serotonergic synapse - Homo sapiens (human); hsa04750 Inflammatory mediator regulation of TRP channels - Homo sapiens (human); hsa04062 Chemokine signaling pathway - Homo sapiens (human); hsa04925 Aldosterone synthesis and secretion - Homo sapiens (human); hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human); hsa04540 Gap junction - Homo sapiens (human); hsa04912 GnRH signaling pathway - Homo sapiens (human); hsa04972 Pancreatic secretion - Homo sapiens (human); hsa05146 Amoebiasis - Homo sapiens (human); hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human); hsa04730 Long-term depression - Homo sapiens (human); hsa04918 Thyroid hormone synthesis - Homo sapiens (human); hsa04742 Taste transduction - Homo sapiens (human); hsa04720 Long-term potentiation - Homo sapiens (human); hsa04961 Endocrine and other factor-regulated calcium reabsorption - Homo sapiens (human); hsa04713 Circadian entrainment - Homo sapiens (human); hsa04926 Relaxin signaling pathway - Homo sapiens (human); hsa04928 Parathyroid hormone synthesis, secretion and action - Homo sapiens (human); ","IPR015359; IPR000909; IPR017946; IPR011993; IPR011992; IPR000008; IPR001711; ","\"Phosphoinositide-specific phospholipase C, EF-hand-like domain; Phosphatidylinositol-specific phospholipase C, X domain; PLC-like phosphodiesterase, TIM beta/alpha-barrel domain; PH domain-like; EF-hand domain pair; C2 domain; Phospholipase C, phosphatidylinositol-specific, Y domain; \"\r"]
["Q15154","Pericentriolar material 1 protein OS=Homo sapiens OX=9606 GN=PCM1","PCM1",228.54,4.1632,1,2,2,2,0.967,0.952,0.888,1.084,0.987,1.124,1.138,0.0513,"nucleus\r","GO:0098840 protein transport along microtubule; GO:0044085 cellular component biogenesis; GO:0034453 microtubule anchoring; GO:0007420 brain development; GO:0051647 nucleus localization; GO:1905508 protein localization to microtubule organizing center; GO:0060271 cilium assembly; GO:0015031 protein transport; GO:0044782 cilium organization; GO:0007610 behavior; GO:0032879 regulation of localization; GO:0044770 cell cycle phase transition; GO:0033365 protein localization to organelle; GO:0008104 protein localization; GO:0044765 single-organism transport; GO:0007399 nervous system development; GO:0000278 mitotic cell cycle; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0048870 cell motility; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0050768 negative regulation of neurogenesis; GO:0006810 transport; GO:0000226 microtubule cytoskeleton organization; GO:0048513 animal organ development; GO:0072393 microtubule anchoring at microtubule organizing center; GO:0007417 central nervous system development; GO:0021846 cell proliferation in forebrain; GO:0051223 regulation of protein transport; GO:0071539 protein localization to centrosome; GO:0010721 negative regulation of cell development; GO:0000086 G2/M transition of mitotic cell cycle; GO:0097435 supramolecular fiber organization; GO:0051640 organelle localization; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0044707 single-multicellular organism process; GO:0051297 centrosome organization; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:1903047 mitotic cell cycle process; GO:0051239 regulation of multicellular organismal process; GO:0030705 cytoskeleton-dependent intracellular transport; GO:0060341 regulation of cellular localization; GO:1902578 single-organism localization; GO:0030900 forebrain development; GO:1902580 single-organism cellular localization; GO:0032880 regulation of protein localization; GO:0051703 intraspecies interaction between organisms; GO:0007275 multicellular organism development; GO:0034613 cellular protein localization; GO:0007010 cytoskeleton organization; GO:0044772 mitotic cell cycle phase transition; GO:0048731 system development; GO:0051960 regulation of nervous system development; GO:0060284 regulation of cell development; GO:0008283 cell proliferation; GO:0071702 organic substance transport; GO:0042073 intraciliary transport; GO:0007017 microtubule-based process; GO:0030031 cell projection assembly; GO:0031122 cytoplasmic microtubule organization; GO:0045184 establishment of protein localization; GO:1904951 positive regulation of establishment of protein localization; GO:0006996 organelle organization; GO:0006928 movement of cell or subcellular component; GO:0044839 cell cycle G2/M phase transition; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:1903827 regulation of cellular protein localization; GO:0051093 negative regulation of developmental process; GO:0051674 localization of cell; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0051241 negative regulation of multicellular organismal process; GO:0051234 establishment of localization; GO:0061351 neural precursor cell proliferation; GO:0010970 transport along microtubule; GO:0051649 establishment of localization in cell; GO:0022607 cellular component assembly; GO:0060322 head development; GO:0001764 neuron migration; GO:0033036 macromolecule localization; GO:0045596 negative regulation of cell differentiation; GO:0032502 developmental process; GO:0032386 regulation of intracellular transport; GO:0035735 intraciliary transport involved in cilium assembly; GO:1902582 single-organism intracellular transport; GO:0051050 positive regulation of transport; GO:1902589 single-organism organelle organization; GO:0051705 multi-organism behavior; GO:0050789 regulation of biological process; GO:0072698 protein localization to microtubule cytoskeleton; GO:0044380 protein localization to cytoskeleton; GO:0030030 cell projection organization; GO:0098727 maintenance of cell number; GO:0040011 locomotion; GO:0099118 microtubule-based protein transport; GO:0048856 anatomical structure development; GO:0051222 positive regulation of protein transport; GO:0031503 protein complex localization; GO:2000026 regulation of multicellular organismal development; GO:0016477 cell migration; GO:0016043 cellular component organization; GO:0090316 positive regulation of intracellular protein transport; GO:1903829 positive regulation of cellular protein localization; GO:0097711 ciliary basal body docking; GO:0022406 membrane docking; GO:0070201 regulation of establishment of protein localization; GO:0099111 microtubule-based transport; GO:0030154 cell differentiation; GO:0035176 social behavior; GO:0070925 organelle assembly; GO:0051961 negative regulation of nervous system development; GO:0006886 intracellular protein transport; GO:0034454 microtubule anchoring at centrosome; GO:0019827 stem cell population maintenance; GO:0009987 cellular process; GO:0033157 regulation of intracellular protein transport; GO:0097150 neuronal stem cell population maintenance; GO:0045595 regulation of cell differentiation; GO:0032388 positive regulation of intracellular transport; GO:0051049 regulation of transport; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0007018 microtubule-based movement; GO:0070727 cellular macromolecule localization; GO:1905515 non-motile cilium assembly; GO:0044767 single-organism developmental process; GO:0031023 microtubule organizing center organization; GO:0022402 cell cycle process; GO:0007049 cell cycle; GO:0022027 interkinetic nuclear migration; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; GO:0050767 regulation of neurogenesis; ","GO:0016020 membrane; GO:0044450 microtubule organizing center part; GO:0031090 organelle membrane; GO:0035869 ciliary transition zone; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0000242 pericentriolar material; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0031965 nuclear membrane; GO:0005815 microtubule organizing center; GO:0015630 microtubule cytoskeleton; GO:0044441 ciliary part; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0045177 apical part of cell; GO:0005929 cilium; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005635 nuclear envelope; GO:0044430 cytoskeletal part; GO:0034451 centriolar satellite; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0036064 ciliary basal body; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005813 centrosome; GO:0031975 envelope; GO:0005814 centriole; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0042802 identical protein binding; GO:0005488 binding; ","K16537",null,null,"IPR031446; ","\"Pericentriolar material 1 protein, C-terminal; \"\r"]
["Q15172","Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R5A","PPP2R5A",56.193,8.7713,6.8,3,4,3,1.077,0.994,0.994,1.007,0.952,0.989,0.962,0.288,"cytoplasm\r","GO:0044700 single organism signaling; GO:0032270 positive regulation of cellular protein metabolic process; GO:0090005 negative regulation of establishment of protein localization to plasma membrane; GO:0051129 negative regulation of cellular component organization; GO:0044699 single-organism process; GO:0019216 regulation of lipid metabolic process; GO:1903729 regulation of plasma membrane organization; GO:0007165 signal transduction; GO:1904375 regulation of protein localization to cell periphery; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0033673 negative regulation of kinase activity; GO:0032879 regulation of localization; GO:0035303 regulation of dephosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0045833 negative regulation of lipid metabolic process; GO:1905476 negative regulation of protein localization to membrane; GO:0051174 regulation of phosphorus metabolic process; GO:1903828 negative regulation of cellular protein localization; GO:0045937 positive regulation of phosphate metabolic process; GO:0080090 regulation of primary metabolic process; GO:0048522 positive regulation of cellular process; GO:0051348 negative regulation of transferase activity; GO:0023052 signaling; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0090219 negative regulation of lipid kinase activity; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0035306 positive regulation of dephosphorylation; GO:0050790 regulation of catalytic activity; GO:0035304 regulation of protein dephosphorylation; GO:0065009 regulation of molecular function; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0043549 regulation of kinase activity; GO:0050794 regulation of cellular process; GO:0060255 regulation of macromolecule metabolic process; GO:0031399 regulation of protein modification process; GO:1903076 regulation of protein localization to plasma membrane; GO:1904376 negative regulation of protein localization to cell periphery; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0070201 regulation of establishment of protein localization; GO:0060341 regulation of cellular localization; GO:1903077 negative regulation of protein localization to plasma membrane; GO:1905475 regulation of protein localization to membrane; GO:0042326 negative regulation of phosphorylation; GO:0051338 regulation of transferase activity; GO:0032880 regulation of protein localization; GO:0090003 regulation of establishment of protein localization to plasma membrane; GO:0009987 cellular process; GO:0035307 positive regulation of protein dephosphorylation; GO:0031401 positive regulation of protein modification process; GO:0048518 positive regulation of biological process; GO:0009892 negative regulation of metabolic process; GO:0051247 positive regulation of protein metabolic process; GO:0051246 regulation of protein metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0010563 negative regulation of phosphorus metabolic process; GO:1904950 negative regulation of establishment of protein localization; GO:0051128 regulation of cellular component organization; GO:1903827 regulation of cellular protein localization; GO:0045936 negative regulation of phosphate metabolic process; GO:0043550 regulation of lipid kinase activity; GO:0065007 biological regulation; ","GO:0030016 myofibril; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0008287 protein serine/threonine phosphatase complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0030018 Z disc; GO:0099080 supramolecular complex; GO:0005623 cell; GO:1903293 phosphatase complex; GO:0031674 I band; GO:0044422 organelle part; GO:0000159 protein phosphatase type 2A complex; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:1902494 catalytic complex; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0043292 contractile fiber; GO:0031430 M band; GO:0043227 membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0005829 cytosol; GO:0099081 supramolecular polymer; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0098687 chromosomal region; GO:0005634 nucleus; GO:0031672 A band; GO:0000775 chromosome, centromeric region; GO:0030017 sarcomere; GO:0044449 contractile fiber part; GO:0044444 cytoplasmic part; ","GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0019888 protein phosphatase regulator activity; GO:0019208 phosphatase regulator activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0019900 kinase binding; GO:0019899 enzyme binding; ","K11584","PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'","hsa04728 Dopaminergic synapse - Homo sapiens (human); hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human); hsa04071 Sphingolipid signaling pathway - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa04152 AMPK signaling pathway - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa03015 mRNA surveillance pathway - Homo sapiens (human); hsa04114 Oocyte meiosis - Homo sapiens (human); ","IPR016024; ","Armadillo-type fold; \r"]
["Q15223","Nectin-1 OS=Homo sapiens OX=9606 GN=NECTIN1","NECTIN1",57.157,5.0403,4.3,2,3,2,0.883,1.007,1.004,1.043,1.053,1.013,1.074,0.177,"extracellular\r","GO:0044409 entry into host; GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0002089 lens morphogenesis in camera-type eye; GO:0070166 enamel mineralization; GO:0048869 cellular developmental process; GO:0048666 neuron development; GO:0045216 cell-cell junction organization; GO:0032989 cellular component morphogenesis; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0002088 lens development in camera-type eye; GO:0050807 regulation of synapse organization; GO:0051234 establishment of localization; GO:0022610 biological adhesion; GO:0009605 response to external stimulus; GO:0000041 transition metal ion transport; GO:0007165 signal transduction; GO:0016337 single organismal cell-cell adhesion; GO:0007154 cell communication; GO:0032990 cell part morphogenesis; GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; GO:0042475 odontogenesis of dentin-containing tooth; GO:0034332 adherens junction organization; GO:0007155 cell adhesion; GO:0048858 cell projection morphogenesis; GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0044419 interspecies interaction between organisms; GO:0090596 sensory organ morphogenesis; GO:0046718 viral entry into host cell; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0009888 tissue development; GO:0002934 desmosome organization; GO:0048699 generation of neurons; GO:0048592 eye morphogenesis; GO:0051963 regulation of synapse assembly; GO:0098609 cell-cell adhesion; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0048812 neuron projection morphogenesis; GO:0023052 signaling; GO:0006935 chemotaxis; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0042476 odontogenesis; GO:0000902 cell morphogenesis; GO:0006810 transport; GO:0030260 entry into host cell; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0030030 cell projection organization; GO:0051828 entry into other organism involved in symbiotic interaction; GO:0098602 single organism cell adhesion; GO:0009887 animal organ morphogenesis; GO:0042330 taxis; GO:0040011 locomotion; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0043010 camera-type eye development; GO:0030001 metal ion transport; GO:0051806 entry into cell of other organism involved in symbiotic interaction; GO:0019058 viral life cycle; GO:0044087 regulation of cellular component biogenesis; GO:0006826 iron ion transport; GO:0050896 response to stimulus; GO:0008037 cell recognition; GO:0051239 regulation of multicellular organismal process; GO:0048468 cell development; GO:0007411 axon guidance; GO:0000904 cell morphogenesis involved in differentiation; GO:0009653 anatomical structure morphogenesis; GO:0001654 eye development; GO:0030154 cell differentiation; GO:0006812 cation transport; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0016032 viral process; GO:0007409 axonogenesis; GO:0007275 multicellular organism development; GO:0031214 biomineral tissue development; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0009987 cellular process; GO:0060041 retina development in camera-type eye; GO:0050803 regulation of synapse structure or activity; GO:0048731 system development; GO:0051960 regulation of nervous system development; GO:0048593 camera-type eye morphogenesis; GO:0002376 immune system process; GO:0051701 interaction with host; GO:0031175 neuron projection development; GO:0034505 tooth mineralization; GO:0061564 axon development; GO:0030182 neuron differentiation; GO:0034330 cell junction organization; GO:0097485 neuron projection guidance; GO:0044767 single-organism developmental process; GO:0006811 ion transport; GO:0097186 amelogenesis; GO:0006928 movement of cell or subcellular component; GO:1902414 protein localization to cell junction; GO:0051128 regulation of cellular component organization; GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules; GO:0006955 immune response; GO:0007423 sensory organ development; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0019898 extrinsic component of membrane; GO:0098796 membrane protein complex; GO:0071944 cell periphery; GO:0044291 cell-cell contact zone; GO:0030054 cell junction; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0030426 growth cone; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005913 cell-cell adherens junction; GO:0005623 cell; GO:0005911 cell-cell junction; GO:0042734 presynaptic membrane; GO:0098590 plasma membrane region; GO:0005622 intracellular; GO:0098793 presynapse; GO:0044464 cell part; GO:0044425 membrane part; GO:0005912 adherens junction; GO:0043005 neuron projection; GO:0097060 synaptic membrane; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0044456 synapse part; GO:0043229 intracellular organelle; GO:0031226 intrinsic component of plasma membrane; GO:0042995 cell projection; GO:0098797 plasma membrane protein complex; GO:0019897 extrinsic component of plasma membrane; GO:0070161 anchoring junction; GO:0044463 cell projection part; GO:0030427 site of polarized growth; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0043296 apical junction complex; GO:0005886 plasma membrane; GO:0045202 synapse; GO:0030424 axon; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044459 plasma membrane part; GO:0032584 growth cone membrane; GO:0016342 catenin complex; GO:0043234 protein complex; GO:0090723 growth cone part; ","GO:0038023 signaling receptor activity; GO:0046982 protein heterodimerization activity; GO:0005102 receptor binding; GO:0015026 coreceptor activity; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:0004871 signal transducer activity; GO:0001618 virus receptor activity; GO:0050839 cell adhesion molecule binding; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0042802 identical protein binding; GO:0005488 binding; GO:0042803 protein homodimerization activity; GO:0030246 carbohydrate binding; GO:0046790 virion binding; ","K06081","PVRL1; poliovirus receptor-related protein 1","hsa04520 Adherens junction - Homo sapiens (human); hsa05168 Herpes simplex infection - Homo sapiens (human); hsa04514 Cell adhesion molecules (CAMs) - Homo sapiens (human); ","IPR003598; IPR007110; IPR013783; IPR013162; IPR003599; IPR013106; ","\"Immunoglobulin subtype 2; Immunoglobulin-like domain; Immunoglobulin-like fold; CD80-like, immunoglobulin C2-set; Immunoglobulin subtype; Immunoglobulin V-set domain; \"\r"]
["Q15257","Serine/threonine-protein phosphatase 2A activator OS=Homo sapiens OX=9606 GN=PTPA","PTPA",40.667,62.225,32.7,8,13,8,1.022,1.025,1.01,1,0.966,1.033,0.981,0.382,"cytoplasm\r","GO:0010941 regulation of cell death; GO:0032270 positive regulation of cellular protein metabolic process; GO:0007067 mitotic nuclear division; GO:0044699 single-organism process; GO:0010923 negative regulation of phosphatase activity; GO:0044237 cellular metabolic process; GO:0031400 negative regulation of protein modification process; GO:0008152 metabolic process; GO:0009893 positive regulation of metabolic process; GO:0044093 positive regulation of molecular function; GO:0035303 regulation of dephosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0000278 mitotic cell cycle; GO:0035305 negative regulation of dephosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0045937 positive regulation of phosphate metabolic process; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0031323 regulation of cellular metabolic process; GO:0043086 negative regulation of catalytic activity; GO:0010605 negative regulation of macromolecule metabolic process; GO:0010942 positive regulation of cell death; GO:0000226 microtubule cytoskeleton organization; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0032516 positive regulation of phosphoprotein phosphatase activity; GO:0035306 positive regulation of dephosphorylation; GO:0051336 regulation of hydrolase activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0035304 regulation of protein dephosphorylation; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:1902850 microtubule cytoskeleton organization involved in mitosis; GO:0006464 cellular protein modification process; GO:0044092 negative regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0036211 protein modification process; GO:0043068 positive regulation of programmed cell death; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0043666 regulation of phosphoprotein phosphatase activity; GO:0032515 negative regulation of phosphoprotein phosphatase activity; GO:0060255 regulation of macromolecule metabolic process; GO:0048285 organelle fission; GO:0031399 regulation of protein modification process; GO:0043067 regulation of programmed cell death; GO:0044267 cellular protein metabolic process; GO:0007051 spindle organization; GO:0043065 positive regulation of apoptotic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:1903047 mitotic cell cycle process; GO:0051346 negative regulation of hydrolase activity; GO:0071704 organic substance metabolic process; GO:0010922 positive regulation of phosphatase activity; GO:0030472 mitotic spindle organization in nucleus; GO:0051345 positive regulation of hydrolase activity; GO:0035308 negative regulation of protein dephosphorylation; GO:0007052 mitotic spindle organization; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0010921 regulation of phosphatase activity; GO:0035307 positive regulation of protein dephosphorylation; GO:0031401 positive regulation of protein modification process; GO:0044238 primary metabolic process; GO:0018208 peptidyl-proline modification; GO:0000413 protein peptidyl-prolyl isomerization; GO:0007017 microtubule-based process; GO:0009892 negative regulation of metabolic process; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0018193 peptidyl-amino acid modification; GO:0051247 positive regulation of protein metabolic process; GO:0006996 organelle organization; GO:0051246 regulation of protein metabolic process; GO:0010563 negative regulation of phosphorus metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0000280 nuclear division; GO:0051248 negative regulation of protein metabolic process; GO:0022402 cell cycle process; GO:0043412 macromolecule modification; GO:0007049 cell cycle; GO:0045936 negative regulation of phosphate metabolic process; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0008287 protein serine/threonine phosphatase complex; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:1903293 phosphatase complex; GO:0044422 organelle part; GO:0000159 protein phosphatase type 2A complex; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:1903561 extracellular vesicle; GO:0034702 ion channel complex; GO:1990351 transporter complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0034703 cation channel complex; GO:0031981 nuclear lumen; GO:1902495 transmembrane transporter complex; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0034704 calcium channel complex; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0043230 extracellular organelle; GO:0044428 nuclear part; ","GO:0008160 protein tyrosine phosphatase activator activity; GO:1901265 nucleoside phosphate binding; GO:0019903 protein phosphatase binding; GO:0005102 receptor binding; GO:0072542 protein phosphatase activator activity; GO:0019888 protein phosphatase regulator activity; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0051721 protein phosphatase 2A binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0042802 identical protein binding; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0019902 phosphatase binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0008047 enzyme activator activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003755 peptidyl-prolyl cis-trans isomerase activity; GO:0005524 ATP binding; GO:0019211 phosphatase activator activity; GO:0046982 protein heterodimerization activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016853 isomerase activity; GO:0030234 enzyme regulator activity; GO:0042803 protein homodimerization activity; GO:0019208 phosphatase regulator activity; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0016859 cis-trans isomerase activity; GO:0019899 enzyme binding; GO:0036094 small molecule binding; ","K17605","PPP2R4; serine/threonine-protein phosphatase 2A activator","hsa04931 Insulin resistance - Homo sapiens (human); "]
["Q15276","Rab GTPase-binding effector protein 1 OS=Homo sapiens OX=9606 GN=RABEP1","RABEP1",99.289,16.919,6.7,5,5,5,0.886,0.998,1.281,0.924,0.888,1.029,0.898,0.45,"nucleus\r","GO:0016043 cellular component organization; GO:0043547 positive regulation of GTPase activity; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0061025 membrane fusion; GO:0071702 organic substance transport; GO:0006897 endocytosis; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0043085 positive regulation of catalytic activity; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:0051336 regulation of hydrolase activity; GO:0008219 cell death; GO:0051345 positive regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0006915 apoptotic process; GO:0061024 membrane organization; GO:0044093 positive regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0065009 regulation of molecular function; GO:0012501 programmed cell death; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0051179 localization; GO:0009987 cellular process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0010008 endosome membrane; GO:0016020 membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044440 endosomal part; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0055037 recycling endosome; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005768 endosome; GO:0031901 early endosome membrane; GO:0030139 endocytic vesicle; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0008083 growth factor activity; GO:0042802 identical protein binding; GO:0030234 enzyme regulator activity; GO:0005102 receptor binding; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0030695 GTPase regulator activity; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0008047 enzyme activator activity; GO:0005096 GTPase activator activity; ","K12480","RABEP1; Rab GTPase-binding effector protein 1","hsa04144 Endocytosis - Homo sapiens (human); ","IPR015390; IPR018514; ","\"Rabaptin, GTPase-Rab5 binding domain; Rabaptin coiled-coil domain; \"\r"]
["Q15293","Reticulocalbin-1 OS=Homo sapiens OX=9606 GN=RCN1","RCN1",38.89,69.932,28.1,8,14,8,1.133,1.136,1.084,0.92,0.901,0.871,0.803,0.000564,"extracellular\r","GO:0032502 developmental process; GO:0044707 single-multicellular organism process; GO:0043010 camera-type eye development; GO:0043009 chordate embryonic development; GO:0048731 system development; GO:0009792 embryo development ending in birth or egg hatching; GO:0044699 single-organism process; GO:0032501 multicellular organismal process; GO:0048513 animal organ development; GO:0001654 eye development; GO:0001701 in utero embryonic development; GO:0044767 single-organism developmental process; GO:0007275 multicellular organism development; GO:0007423 sensory organ development; GO:0009790 embryo development; GO:0048856 anatomical structure development; ","GO:0005788 endoplasmic reticulum lumen; GO:0043229 intracellular organelle; GO:0005783 endoplasmic reticulum; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044432 endoplasmic reticulum part; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0005509 calcium ion binding; GO:0005488 binding; GO:0043167 ion binding; ",{"$nulls":3},"IPR002048; IPR011992; ","EF-hand domain; EF-hand domain pair; \r"]
["Q15365","Poly(rC)-binding protein 1 OS=Homo sapiens OX=9606 GN=PCBP1","PCBP1",37.497,192.11,57.9,14,33,9,0.957,0.948,0.931,1.03,1.076,1.073,1.121,0.00218,"cytoskeleton\r","GO:0019079 viral genome replication; GO:0009891 positive regulation of biosynthetic process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0039703 RNA replication; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0006396 RNA processing; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0031323 regulation of cellular metabolic process; GO:0051704 multi-organism process; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0039694 viral RNA genome replication; GO:0016071 mRNA metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0019058 viral life cycle; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0016032 viral process; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0051254 positive regulation of RNA metabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0006807 nitrogen compound metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0031325 positive regulation of cellular metabolic process; GO:0010467 gene expression; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0000932 P-body; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0035770 ribonucleoprotein granule; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding; GO:0003677 DNA binding; GO:0003723 RNA binding; GO:0098847 sequence-specific single stranded DNA binding; GO:0003697 single-stranded DNA binding; GO:0005515 protein binding; GO:0043565 sequence-specific DNA binding; GO:0003700 transcription factor activity, sequence-specific DNA binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0003729 mRNA binding; GO:0050839 cell adhesion molecule binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0003676 nucleic acid binding; GO:0001071 nucleic acid binding transcription factor activity; ","K12889","PCBP1; poly(rC)-binding protein 1","hsa03040 Spliceosome - Homo sapiens (human); hsa04216 Ferroptosis - Homo sapiens (human); ","IPR004087; IPR004088; ","\"K Homology domain; K Homology domain, type 1; \"\r"]
["Q15370","Elongin-B OS=Homo sapiens OX=9606 GN=ELOB","ELOB",13.133,22.798,40.7,5,11,5,0.971,1.069,0.969,1.05,1.005,1,1.015,0.679,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0097659 nucleic acid-templated transcription; GO:0009058 biosynthetic process; GO:0006354 DNA-templated transcription, elongation; GO:0044237 cellular metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0070887 cellular response to chemical stimulus; GO:0051716 cellular response to stimulus; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0071822 protein complex subunit organization; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0031323 regulation of cellular metabolic process; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006464 cellular protein modification process; GO:0070271 protein complex biogenesis; GO:0036211 protein modification process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0033554 cellular response to stress; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0009628 response to abiotic stimulus; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0001666 response to hypoxia; GO:0070482 response to oxygen levels; GO:0043620 regulation of DNA-templated transcription in response to stress; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0071453 cellular response to oxygen levels; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0071456 cellular response to hypoxia; GO:0006355 regulation of transcription, DNA-templated; GO:0006950 response to stress; GO:0016567 protein ubiquitination; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006368 transcription elongation from RNA polymerase II promoter; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia; GO:0044238 primary metabolic process; GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress; GO:0051252 regulation of RNA metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0032446 protein modification by small protein conjugation; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0006366 transcription from RNA polymerase II promoter; GO:0010467 gene expression; GO:0036293 response to decreased oxygen levels; GO:0043412 macromolecule modification; GO:0036294 cellular response to decreased oxygen levels; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0000153 cytoplasmic ubiquitin ligase complex; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0070449 elongin complex; GO:1903561 extracellular vesicle; GO:0000151 ubiquitin ligase complex; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0031461 cullin-RING ubiquitin ligase complex; GO:0031981 nuclear lumen; GO:0031462 Cul2-RING ubiquitin ligase complex; GO:1990234 transferase complex; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0030891 VCB complex; GO:0008023 transcription elongation factor complex; GO:0031466 Cul5-RING ubiquitin ligase complex; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0031625 ubiquitin protein ligase binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0005488 binding; GO:0019899 enzyme binding; ","K03873","TCEB2; transcription elongation factor B, polypeptide 2","hsa05200 Pathways in cancer - Homo sapiens (human); hsa04066 HIF-1 signaling pathway - Homo sapiens (human); hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human); hsa05211 Renal cell carcinoma - Homo sapiens (human); ","IPR029071; IPR000626; ","Ubiquitin-related domain; Ubiquitin domain; \r"]
["Q15386","Ubiquitin-protein ligase E3C OS=Homo sapiens OX=9606 GN=UBE3C","UBE3C",123.92,3.4863,1.6,2,2,2,1.075,0.975,1.012,1.033,1.008,0.911,0.964,0.48,"nucleus\r","GO:0016567 protein ubiquitination; GO:0044267 cellular protein metabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0000209 protein polyubiquitination; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0032446 protein modification by small protein conjugation; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:0009987 cellular process; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:1902494 catalytic complex; GO:0005634 nucleus; GO:0000502 proteasome complex; GO:0044464 cell part; GO:0005622 intracellular; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:1905368 peptidase complex; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:1905369 endopeptidase complex; ","GO:0005515 protein binding; GO:0019787 ubiquitin-like protein transferase activity; GO:0016740 transferase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0004842 ubiquitin-protein transferase activity; ","K10589","UBE3C; ubiquitin-protein ligase E3 C [EC:2.3.2.26]","hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human); ","IPR000569; ","HECT domain; \r"]
["Q15417","Calponin-3 OS=Homo sapiens OX=9606 GN=CNN3","CNN3",36.413,26.049,21.6,6,12,4,0.979,0.981,0.955,1.064,0.95,1.076,1.06,0.235,"cytoplasm\r","GO:0016043 cellular component organization; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0051346 negative regulation of hydrolase activity; GO:0022610 biological adhesion; GO:0032780 negative regulation of ATPase activity; GO:0030154 cell differentiation; GO:0030036 actin cytoskeleton organization; GO:0007155 cell adhesion; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0032502 developmental process; GO:0031032 actomyosin structure organization; GO:0060429 epithelium development; GO:0009888 tissue development; GO:0044763 single-organism cellular process; GO:0098609 cell-cell adhesion; GO:0043086 negative regulation of catalytic activity; GO:1902589 single-organism organelle organization; GO:0051336 regulation of hydrolase activity; GO:0043462 regulation of ATPase activity; GO:0006996 organelle organization; GO:0050790 regulation of catalytic activity; GO:0044767 single-organism developmental process; GO:0030029 actin filament-based process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0048856 anatomical structure development; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:0030855 epithelial cell differentiation; ","GO:0030425 dendrite; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0043025 neuronal cell body; GO:0044424 intracellular part; GO:0005913 cell-cell adherens junction; GO:0005911 cell-cell junction; GO:0005623 cell; GO:0032279 asymmetric synapse; GO:0043197 dendritic spine; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0005925 focal adhesion; GO:0044309 neuron spine; GO:0044464 cell part; GO:0005622 intracellular; GO:0014069 postsynaptic density; GO:0005912 adherens junction; GO:0043005 neuron projection; GO:0030055 cell-substrate junction; GO:0097458 neuron part; GO:0098984 neuron to neuron synapse; GO:0005924 cell-substrate adherens junction; GO:0044456 synapse part; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0070161 anchoring junction; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0015629 actin cytoskeleton; GO:0045202 synapse; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0098794 postsynapse; GO:0044297 cell body; GO:0099572 postsynaptic specialization; GO:0044444 cytoplasmic part; ","GO:0098641 cadherin binding involved in cell-cell adhesion; GO:0050839 cell adhesion molecule binding; GO:0008092 cytoskeletal protein binding; GO:0098631 protein binding involved in cell adhesion; GO:0008017 microtubule binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0003779 actin binding; GO:0015631 tubulin binding; GO:0005515 protein binding; GO:0098632 protein binding involved in cell-cell adhesion; GO:0005516 calmodulin binding; ",{"$nulls":3},"IPR001715; ","Calponin homology domain; \r"]
["Q15427","Splicing factor 3B subunit 4 OS=Homo sapiens OX=9606 GN=SF3B4","SF3B4",44.385,5.8473,5.9,2,2,2,0.883,1.023,0.95,1.071,1.031,1.045,1.102,0.0879,"nucleus\r","GO:0033120 positive regulation of RNA splicing; GO:0050794 regulation of cellular process; GO:0050685 positive regulation of mRNA processing; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0008152 metabolic process; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0009893 positive regulation of metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0010628 positive regulation of gene expression; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0048024 regulation of mRNA splicing, via spliceosome; GO:0006396 RNA processing; GO:0010468 regulation of gene expression; GO:0051254 positive regulation of RNA metabolic process; GO:0080090 regulation of primary metabolic process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0050684 regulation of mRNA processing; GO:0031323 regulation of cellular metabolic process; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:1903313 positive regulation of mRNA metabolic process; GO:0043484 regulation of RNA splicing; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:1903311 regulation of mRNA metabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0048026 positive regulation of mRNA splicing, via spliceosome; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0010467 gene expression; GO:0016071 mRNA metabolic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005681 spliceosomal complex; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0005689 U12-type spliceosomal complex; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:1901265 nucleoside phosphate binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0036094 small molecule binding; ","K12831","SF3B4; splicing factor 3B subunit 4","hsa03040 Spliceosome - Homo sapiens (human); ","IPR034158; IPR000504; IPR012677; IPR034159; ","\"SF3B4, RNA recognition motif 1; RNA recognition motif domain; Nucleotide-binding alpha-beta plait domain; SF3B4, RNA recognition motif 2; \"\r"]
["Q15435","Protein phosphatase 1 regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PPP1R7","PPP1R7",41.564,72.377,28.9,9,14,9,1.037,0.994,1.021,0.967,1.009,1.021,0.982,0.425,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0032270 positive regulation of cellular protein metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0031399 regulation of protein modification process; GO:0044699 single-organism process; GO:0009893 positive regulation of metabolic process; GO:0035303 regulation of dephosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0009987 cellular process; GO:0007059 chromosome segregation; GO:0051174 regulation of phosphorus metabolic process; GO:0045937 positive regulation of phosphate metabolic process; GO:0035307 positive regulation of protein dephosphorylation; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0031401 positive regulation of protein modification process; GO:0031323 regulation of cellular metabolic process; GO:0048518 positive regulation of biological process; GO:0051247 positive regulation of protein metabolic process; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0035306 positive regulation of dephosphorylation; GO:0050790 regulation of catalytic activity; GO:0051246 regulation of protein metabolic process; GO:0035304 regulation of protein dephosphorylation; GO:0031325 positive regulation of cellular metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0005515 protein binding; GO:0030234 enzyme regulator activity; GO:0098772 molecular function regulator; GO:0005488 binding; GO:0019888 protein phosphatase regulator activity; GO:0019208 phosphatase regulator activity; ","K17550",null,null,"IPR003603; IPR032675; ","\"U2A'/phosphoprotein 32 family A, C-terminal; Leucine-rich repeat domain, L domain-like; \"\r"]
["Q15436","Protein transport protein Sec23A OS=Homo sapiens OX=9606 GN=SEC23A","SEC23A",86.16,105.3,26.5,16,28,14,1.072,1.05,1.067,0.916,0.951,0.987,0.895,0.00768,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0051640 organelle localization; GO:0016043 cellular component organization; GO:0006901 vesicle coating; GO:0046907 intracellular transport; GO:0048207 vesicle targeting, rough ER to cis-Golgi; GO:0048208 COPII vesicle coating; GO:0044699 single-organism process; GO:0048193 Golgi vesicle transport; GO:0006903 vesicle targeting; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0051649 establishment of localization in cell; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0051648 vesicle localization; GO:0048199 vesicle targeting, to, from or within Golgi; GO:0006886 intracellular protein transport; GO:0034613 cellular protein localization; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0051650 establishment of vesicle localization; GO:0071822 protein complex subunit organization; GO:0090114 COPII-coated vesicle budding; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:0048002 antigen processing and presentation of peptide antigen; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0016050 vesicle organization; GO:0071702 organic substance transport; GO:0002376 immune system process; GO:0051656 establishment of organelle localization; GO:0002495 antigen processing and presentation of peptide antigen via MHC class II; GO:0043933 macromolecular complex subunit organization; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0019882 antigen processing and presentation; GO:0070727 cellular macromolecule localization; GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0006900 membrane budding; GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II; GO:0051179 localization; GO:0070271 protein complex biogenesis; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0071840 cellular component organization or biogenesis; ","GO:0005790 smooth endoplasmic reticulum; GO:0030658 transport vesicle membrane; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0030120 vesicle coat; GO:0005623 cell; GO:0030662 coated vesicle membrane; GO:0044422 organelle part; GO:0097425 smooth endoplasmic reticulum part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0048471 perinuclear region of cytoplasm; GO:0044431 Golgi apparatus part; GO:0043227 membrane-bounded organelle; GO:0030868 smooth endoplasmic reticulum membrane; GO:0005789 endoplasmic reticulum membrane; GO:0012507 ER to Golgi transport vesicle membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0048475 coated membrane; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0030134 ER to Golgi transport vesicle; GO:0005829 cytosol; GO:0030135 coated vesicle; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044432 endoplasmic reticulum part; GO:0030117 membrane coat; GO:0030127 COPII vesicle coat; GO:0043234 protein complex; GO:0005794 Golgi apparatus; GO:0030133 transport vesicle; GO:0044444 cytoplasmic part; ","GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0008270 zinc ion binding; GO:0046914 transition metal ion binding; GO:0005488 binding; GO:0043167 ion binding; ","K14006","SEC23; protein transport protein SEC23","hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); ","IPR006900; IPR012990; IPR006896; IPR006895; IPR029006; IPR007123; IPR002035; ","\"Sec23/Sec24, helical domain; Sec23/Sec24 beta-sandwich; Sec23/Sec24, trunk domain; Zinc finger, Sec23/Sec24-type; ADF-H/Gelsolin-like domain; Gelsolin-like domain; von Willebrand factor, type A; \"\r"]
["Q15517","Corneodesmosin OS=Homo sapiens OX=9606 GN=CDSN","CDSN",51.522,10.309,5.7,2,3,2,0.932,0.867,0.873,1.103,1.131,1.089,1.244,0.00104,"extracellular\r","GO:0043589 skin morphogenesis; GO:0044707 single-multicellular organism process; GO:0031424 keratinization; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0009913 epidermal cell differentiation; GO:0022610 biological adhesion; GO:0009653 anatomical structure morphogenesis; GO:0030154 cell differentiation; GO:0016337 single organismal cell-cell adhesion; GO:0008544 epidermis development; GO:0007155 cell adhesion; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0043588 skin development; GO:0009888 tissue development; GO:0030216 keratinocyte differentiation; GO:0048731 system development; GO:0070268 cornification; GO:0098609 cell-cell adhesion; GO:0044763 single-organism cellular process; GO:0032501 multicellular organismal process; GO:0048513 animal organ development; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0098602 single organism cell adhesion; GO:0009887 animal organ morphogenesis; GO:0012501 programmed cell death; GO:0048856 anatomical structure development; GO:0030855 epithelial cell differentiation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0070161 anchoring junction; GO:0005911 cell-cell junction; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0030057 desmosome; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0001533 cornified envelope; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0005515 protein binding; GO:0042802 identical protein binding; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0046983 protein dimerization activity; "]
["Q15526","Surfeit locus protein 1 OS=Homo sapiens OX=9606 GN=SURF1","SURF1",33.331,6.3579,5.3,1,1,1,0.909,0.971,1.014,0.967,1.052,1.086,1.073,0.21,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0009163 nucleoside biosynthetic process; GO:0046129 purine ribonucleoside biosynthetic process; GO:0009156 ribonucleoside monophosphate biosynthetic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0046390 ribose phosphate biosynthetic process; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0006091 generation of precursor metabolites and energy; GO:0097034 mitochondrial respiratory chain complex IV biogenesis; GO:0022607 cellular component assembly; GO:0006753 nucleoside phosphate metabolic process; GO:0065003 macromolecular complex assembly; GO:0007005 mitochondrion organization; GO:0019693 ribose phosphate metabolic process; GO:0044765 single-organism transport; GO:0009145 purine nucleoside triphosphate biosynthetic process; GO:0018130 heterocycle biosynthetic process; GO:0098655 cation transmembrane transport; GO:0009206 purine ribonucleoside triphosphate biosynthetic process; GO:0071822 protein complex subunit organization; GO:0008535 respiratory chain complex IV assembly; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0006754 ATP biosynthetic process; GO:0006119 oxidative phosphorylation; GO:0044763 single-organism cellular process; GO:0072521 purine-containing compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0009168 purine ribonucleoside monophosphate biosynthetic process; GO:0042451 purine nucleoside biosynthetic process; GO:0006810 transport; GO:0090407 organophosphate biosynthetic process; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0072522 purine-containing compound biosynthetic process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0033617 mitochondrial respiratory chain complex IV assembly; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0006164 purine nucleotide biosynthetic process; GO:0070271 protein complex biogenesis; GO:0098662 inorganic cation transmembrane transport; GO:1901362 organic cyclic compound biosynthetic process; GO:0033108 mitochondrial respiratory chain complex assembly; GO:0009201 ribonucleoside triphosphate biosynthetic process; GO:0016043 cellular component organization; GO:0016310 phosphorylation; GO:0034220 ion transmembrane transport; GO:0009165 nucleotide biosynthetic process; GO:0017004 cytochrome complex assembly; GO:0006725 cellular aromatic compound metabolic process; GO:0009259 ribonucleotide metabolic process; GO:0009142 nucleoside triphosphate biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0006812 cation transport; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1902600 hydrogen ion transmembrane transport; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0009119 ribonucleoside metabolic process; GO:0006461 protein complex assembly; GO:0043623 cellular protein complex assembly; GO:0046034 ATP metabolic process; GO:0009124 nucleoside monophosphate biosynthetic process; GO:0034622 cellular macromolecular complex assembly; GO:0044711 single-organism biosynthetic process; GO:0098660 inorganic ion transmembrane transport; GO:0009127 purine nucleoside monophosphate biosynthetic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0042455 ribonucleoside biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0045333 cellular respiration; GO:0015992 proton transport; GO:0006818 hydrogen transport; GO:0044249 cellular biosynthetic process; GO:0006163 purine nucleotide metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0055085 transmembrane transport; GO:0046128 purine ribonucleoside metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0009152 purine ribonucleotide biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0006811 ion transport; GO:1901659 glycosyl compound biosynthetic process; GO:0006996 organelle organization; GO:0009060 aerobic respiration; GO:0009260 ribonucleotide biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0051179 localization; GO:0015672 monovalent inorganic cation transport; GO:1901564 organonitrogen compound metabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044429 mitochondrial part; GO:0031090 organelle membrane; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0005746 mitochondrial respiratory chain; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005740 mitochondrial envelope; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0031975 envelope; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0070469 respiratory chain; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0015075 ion transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0015077 monovalent inorganic cation transmembrane transporter activity; GO:0016676 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor; GO:0016675 oxidoreductase activity, acting on a heme group of donors; GO:0015078 hydrogen ion transmembrane transporter activity; GO:0015002 heme-copper terminal oxidase activity; GO:0016491 oxidoreductase activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0009055 electron carrier activity; GO:0004129 cytochrome-c oxidase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0022890 inorganic cation transmembrane transporter activity; GO:0008324 cation transmembrane transporter activity; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; ","K14998"]
["Q15631","Translin OS=Homo sapiens OX=9606 GN=TSN","TSN",26.183,46.078,40.8,9,16,9,1.012,1,0.98,0.982,1.024,0.948,0.987,0.614,"cytoplasm\r","GO:0006725 cellular aromatic compound metabolic process; GO:0006259 DNA metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0044699 single-organism process; GO:0048519 negative regulation of biological process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0009987 cellular process; GO:0006310 DNA recombination; GO:0010468 regulation of gene expression; GO:0010629 negative regulation of gene expression; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0044238 primary metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0009892 negative regulation of metabolic process; GO:0016070 RNA metabolic process; GO:0016458 gene silencing; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0031047 gene silencing by RNA; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0090305 nucleic acid phosphodiester bond hydrolysis; GO:0065007 biological regulation; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0005829 cytosol; GO:0044444 cytoplasmic part; ","GO:0003677 DNA binding; GO:0003723 RNA binding; GO:0044877 macromolecular complex binding; GO:0003697 single-stranded DNA binding; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0043565 sequence-specific DNA binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0003729 mRNA binding; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0004518 nuclease activity; GO:0004519 endonuclease activity; GO:0032403 protein complex binding; ",{"$nulls":3},"IPR016069; IPR016068; ","\"Translin, C-terminal; Translin, N-terminal; \"\r"]
["Q15642","Cdc42-interacting protein 4 OS=Homo sapiens OX=9606 GN=TRIP10","TRIP10",68.351,24.59,14.1,8,8,8,1.002,1.114,1.207,0.942,0.881,0.861,0.808,0.0247,"nucleus\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0016043 cellular component organization; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:0030036 actin cytoskeleton organization; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0051345 positive regulation of hydrolase activity; GO:0044093 positive regulation of molecular function; GO:0007010 cytoskeleton organization; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:0051056 regulation of small GTPase mediated signal transduction; GO:0051716 cellular response to stimulus; GO:1902531 regulation of intracellular signal transduction; GO:0043547 positive regulation of GTPase activity; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0023052 signaling; GO:0006897 endocytosis; GO:0043085 positive regulation of catalytic activity; GO:0006810 transport; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0006996 organelle organization; GO:0048583 regulation of response to stimulus; GO:0061024 membrane organization; GO:0030029 actin filament-based process; GO:0065009 regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0051179 localization; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005938 cell cortex; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0099568 cytoplasmic region; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005764 lysosome; GO:0001891 phagocytic cup; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0005773 vacuole; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0042802 identical protein binding; GO:0030234 enzyme regulator activity; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0005488 binding; GO:0030695 GTPase regulator activity; GO:0008289 lipid binding; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0008047 enzyme activator activity; GO:0005096 GTPase activator activity; ","K07196","TRIP10; thyroid hormone receptor interactor 10","hsa04910 Insulin signaling pathway - Homo sapiens (human); ","IPR001452; IPR031160; IPR001060; ","SH3 domain; F-BAR domain; FCH domain; \r"]
["Q15691","Microtubule-associated protein RP/EB family member 1 OS=Homo sapiens OX=9606 GN=MAPRE1","MAPRE1",29.999,38.332,33.6,8,10,7,0.97,0.987,1.062,0.99,1.078,0.949,0.999,0.979,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0030335 positive regulation of cell migration; GO:0031111 negative regulation of microtubule polymerization or depolymerization; GO:0040017 positive regulation of locomotion; GO:0051129 negative regulation of cellular component organization; GO:0007067 mitotic nuclear division; GO:0032092 positive regulation of protein binding; GO:1904527 negative regulation of microtubule binding; GO:0060271 cilium assembly; GO:0044699 single-organism process; GO:0031110 regulation of microtubule polymerization or depolymerization; GO:0032091 negative regulation of protein binding; GO:0044782 cilium organization; GO:0000819 sister chromatid segregation; GO:1904528 positive regulation of microtubule binding; GO:0022607 cellular component assembly; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0032271 regulation of protein polymerization; GO:0044770 cell cycle phase transition; GO:0051493 regulation of cytoskeleton organization; GO:0033365 protein localization to organelle; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0051099 positive regulation of binding; GO:0031333 negative regulation of protein complex assembly; GO:0000278 mitotic cell cycle; GO:0007059 chromosome segregation; GO:0051494 negative regulation of cytoskeleton organization; GO:0051098 regulation of binding; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0031113 regulation of microtubule polymerization; GO:0051272 positive regulation of cellular component movement; GO:0032886 regulation of microtubule-based process; GO:0010639 negative regulation of organelle organization; GO:1902589 single-organism organelle organization; GO:0043254 regulation of protein complex assembly; GO:0044380 protein localization to cytoskeleton; GO:0072698 protein localization to microtubule cytoskeleton; GO:0050789 regulation of biological process; GO:0030030 cell projection organization; GO:0051100 negative regulation of binding; GO:1902904 negative regulation of supramolecular fiber organization; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0051301 cell division; GO:0000086 G2/M transition of mitotic cell cycle; GO:1902903 regulation of supramolecular fiber organization; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:1903033 positive regulation of microtubule plus-end binding; GO:0048285 organelle fission; GO:0044087 regulation of cellular component biogenesis; GO:0097711 ciliary basal body docking; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:2000147 positive regulation of cell motility; GO:1904526 regulation of microtubule binding; GO:1903047 mitotic cell cycle process; GO:0022406 membrane docking; GO:0031115 negative regulation of microtubule polymerization; GO:0043393 regulation of protein binding; GO:0070925 organelle assembly; GO:2000145 regulation of cell motility; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0044772 mitotic cell cycle phase transition; GO:1903031 regulation of microtubule plus-end binding; GO:0070507 regulation of microtubule cytoskeleton organization; GO:0051270 regulation of cellular component movement; GO:0033043 regulation of organelle organization; GO:0030334 regulation of cell migration; GO:0008283 cell proliferation; GO:0048518 positive regulation of biological process; GO:0035372 protein localization to microtubule; GO:0030031 cell projection assembly; GO:0051641 cellular localization; GO:0070727 cellular macromolecule localization; GO:0051276 chromosome organization; GO:0098813 nuclear chromosome segregation; GO:0006996 organelle organization; GO:0000280 nuclear division; GO:0044839 cell cycle G2/M phase transition; GO:0007062 sister chromatid cohesion; GO:0051128 regulation of cellular component organization; GO:0022402 cell cycle process; GO:0032272 negative regulation of protein polymerization; GO:0040012 regulation of locomotion; GO:0051179 localization; GO:0007049 cell cycle; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0005938 cell cortex; GO:0005874 microtubule; GO:0005881 cytoplasmic microtubule; GO:0035371 microtubule plus-end; GO:0071944 cell periphery; GO:0099568 cytoplasmic region; GO:0005737 cytoplasm; GO:0030863 cortical cytoskeleton; GO:1990752 microtubule end; GO:0044424 intracellular part; GO:0099512 supramolecular fiber; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0005815 microtubule organizing center; GO:0098590 plasma membrane region; GO:0015630 microtubule cytoskeleton; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0030981 cortical microtubule cytoskeleton; GO:0043227 membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0099513 polymeric cytoskeletal fiber; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044463 cell projection part; GO:0005829 cytosol; GO:0005886 plasma membrane; GO:0099081 supramolecular polymer; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0005813 centrosome; GO:0044448 cell cortex part; GO:0031253 cell projection membrane; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0050839 cell adhesion molecule binding; GO:0003723 RNA binding; GO:0042802 identical protein binding; GO:0008092 cytoskeletal protein binding; GO:0008017 microtubule binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0003676 nucleic acid binding; GO:0015631 tubulin binding; GO:0008022 protein C-terminus binding; GO:0005515 protein binding; GO:0051010 microtubule plus-end binding; ","K10436",null,null,"IPR001715; IPR004953; ","\"Calponin homology domain; EB1, C-terminal; \"\r"]
["Q15717","ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1","ELAVL1",36.091,31.635,12.6,4,5,4,1.006,0.951,0.967,1.026,1.006,1.041,1.051,0.0618,"nucleus\r","GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0010608 posttranscriptional regulation of gene expression; GO:0043489 RNA stabilization; GO:0009891 positive regulation of biosynthetic process; GO:0044699 single-organism process; GO:2000036 regulation of stem cell population maintenance; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0060149 negative regulation of posttranscriptional gene silencing; GO:0032502 developmental process; GO:0006396 RNA processing; GO:0010468 regulation of gene expression; GO:0060147 regulation of posttranscriptional gene silencing; GO:0031326 regulation of cellular biosynthetic process; GO:0045727 positive regulation of translation; GO:0080090 regulation of primary metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0060967 negative regulation of gene silencing by RNA; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0048856 anatomical structure development; GO:0016071 mRNA metabolic process; GO:0048255 mRNA stabilization; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0051239 regulation of multicellular organismal process; GO:0043487 regulation of RNA stability; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0060964 regulation of gene silencing by miRNA; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0060969 negative regulation of gene silencing; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0060968 regulation of gene silencing; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0008380 RNA splicing; GO:0070935 3'-UTR-mediated mRNA stabilization; GO:0060965 negative regulation of gene silencing by miRNA; GO:0006807 nitrogen compound metabolic process; GO:0060966 regulation of gene silencing by RNA; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:0043488 regulation of mRNA stability; GO:0048518 positive regulation of biological process; GO:0034248 regulation of cellular amide metabolic process; GO:0051247 positive regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0006417 regulation of translation; GO:0031325 positive regulation of cellular metabolic process; GO:0034250 positive regulation of cellular amide metabolic process; GO:0010467 gene expression; GO:0031328 positive regulation of cellular biosynthetic process; GO:0050793 regulation of developmental process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1990904 ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0003723 RNA binding; GO:0017091 AU-rich element binding; GO:1901265 nucleoside phosphate binding; GO:0003725 double-stranded RNA binding; GO:0003730 mRNA 3'-UTR binding; GO:0046983 protein dimerization activity; GO:0019901 protein kinase binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0035925 mRNA 3'-UTR AU-rich region binding; GO:0019900 kinase binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0003729 mRNA binding; GO:0042802 identical protein binding; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0019899 enzyme binding; GO:0036094 small molecule binding; ","K13088","ELAVL1; ELAV-like protein 1","hsa04657 IL-17 signaling pathway - Homo sapiens (human); hsa04152 AMPK signaling pathway - Homo sapiens (human); ","IPR000504; IPR012677; ","RNA recognition motif domain; Nucleotide-binding alpha-beta plait domain; \r"]
["Q15750","TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 OS=Homo sapiens OX=9606 GN=TAB1","TAB1",54.643,7.4022,6.5,3,3,3,1.275,0.943,1.076,0.703,0.899,1.114,0.825,0.271,"nucleus\r","GO:0044700 single organism signaling; GO:0032270 positive regulation of cellular protein metabolic process; GO:0002220 innate immune response activating cell surface receptor signaling pathway; GO:0007166 cell surface receptor signaling pathway; GO:0043009 chordate embryonic development; GO:0030323 respiratory tube development; GO:0000185 activation of MAPKKK activity; GO:0035872 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; GO:0031347 regulation of defense response; GO:0044237 cellular metabolic process; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway; GO:0008152 metabolic process; GO:0007507 heart development; GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0044093 positive regulation of molecular function; GO:0030522 intracellular receptor signaling pathway; GO:0009719 response to endogenous stimulus; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0070848 response to growth factor; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0051347 positive regulation of transferase activity; GO:0009790 embryo development; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0051174 regulation of phosphorus metabolic process; GO:0002758 innate immune response-activating signal transduction; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0031323 regulation of cellular metabolic process; GO:0071559 response to transforming growth factor beta; GO:0032501 multicellular organismal process; GO:0050776 regulation of immune response; GO:0060976 coronary vasculature development; GO:0000165 MAPK cascade; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0051092 positive regulation of NF-kappaB transcription factor activity; GO:0002223 stimulatory C-type lectin receptor signaling pathway; GO:0001701 in utero embryonic development; GO:0044710 single-organism metabolic process; GO:0051090 regulation of sequence-specific DNA binding transcription factor activity; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0009887 animal organ morphogenesis; GO:0002682 regulation of immune system process; GO:0006464 cellular protein modification process; GO:0002755 MyD88-dependent toll-like receptor signaling pathway; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0072359 circulatory system development; GO:0050794 regulation of cellular process; GO:0016310 phosphorylation; GO:0033554 cellular response to stress; GO:0044707 single-multicellular organism process; GO:0002753 cytoplasmic pattern recognition receptor signaling pathway; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0080134 regulation of response to stress; GO:0071902 positive regulation of protein serine/threonine kinase activity; GO:0009653 anatomical structure morphogenesis; GO:0031349 positive regulation of defense response; GO:0032147 activation of protein kinase activity; GO:0009889 regulation of biosynthetic process; GO:0060541 respiratory system development; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0038093 Fc receptor signaling pathway; GO:0050778 positive regulation of immune response; GO:0009966 regulation of signal transduction; GO:0023014 signal transduction by protein phosphorylation; GO:0002253 activation of immune response; GO:1902531 regulation of intracellular signal transduction; GO:0006950 response to stress; GO:0003279 cardiac septum development; GO:0048731 system development; GO:0007179 transforming growth factor beta receptor signaling pathway; GO:0002376 immune system process; GO:0072358 cardiovascular system development; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0043406 positive regulation of MAP kinase activity; GO:0051247 positive regulation of protein metabolic process; GO:0006793 phosphorus metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0007249 I-kappaB kinase/NF-kappaB signaling; GO:0043412 macromolecule modification; GO:0048584 positive regulation of response to stimulus; GO:0070646 protein modification by small protein removal; GO:0001568 blood vessel development; GO:0023051 regulation of signaling; GO:0071560 cellular response to transforming growth factor beta stimulus; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0071363 cellular response to growth factor stimulus; GO:0031098 stress-activated protein kinase signaling cascade; GO:0006796 phosphate-containing compound metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0045088 regulation of innate immune response; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0002221 pattern recognition receptor signaling pathway; GO:0033674 positive regulation of kinase activity; GO:0070887 cellular response to chemical stimulus; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0030324 lung development; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0035295 tube development; GO:0045937 positive regulation of phosphate metabolic process; GO:0031326 regulation of cellular biosynthetic process; GO:0003007 heart morphogenesis; GO:0048522 positive regulation of cellular process; GO:0001944 vasculature development; GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity; GO:0070647 protein modification by small protein conjugation or removal; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0035904 aorta development; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0002224 toll-like receptor signaling pathway; GO:0060840 artery development; GO:0007254 JNK cascade; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0043549 regulation of kinase activity; GO:0045859 regulation of protein kinase activity; GO:0002218 activation of innate immune response; GO:0060255 regulation of macromolecule metabolic process; GO:0043405 regulation of MAP kinase activity; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0071310 cellular response to organic substance; GO:0050896 response to stimulus; GO:0016579 protein deubiquitination; GO:0071704 organic substance metabolic process; GO:0006468 protein phosphorylation; GO:0043408 regulation of MAPK cascade; GO:0023056 positive regulation of signaling; GO:0002757 immune response-activating signal transduction; GO:0006508 proteolysis; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:0051403 stress-activated MAPK cascade; GO:0006355 regulation of transcription, DNA-templated; GO:0045089 positive regulation of innate immune response; GO:0035556 intracellular signal transduction; GO:0009792 embryo development ending in birth or egg hatching; GO:0001932 regulation of protein phosphorylation; GO:0031401 positive regulation of protein modification process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0001934 positive regulation of protein phosphorylation; GO:0045860 positive regulation of protein kinase activity; GO:0006470 protein dephosphorylation; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0016311 dephosphorylation; GO:0003205 cardiac chamber development; GO:0043085 positive regulation of catalytic activity; GO:0000187 activation of MAPK activity; GO:0071495 cellular response to endogenous stimulus; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0002684 positive regulation of immune system process; GO:0038095 Fc-epsilon receptor signaling pathway; GO:0009967 positive regulation of signal transduction; GO:0043410 positive regulation of MAPK cascade; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0010008 endosome membrane; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0004722 protein serine/threonine phosphatase activity; GO:0016791 phosphatase activity; GO:0044877 macromolecular complex binding; GO:0019901 protein kinase binding; GO:0051019 mitogen-activated protein kinase binding; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0019207 kinase regulator activity; GO:0004721 phosphoprotein phosphatase activity; GO:0019900 kinase binding; GO:0098772 molecular function regulator; GO:0019209 kinase activator activity; GO:0030234 enzyme regulator activity; GO:0042578 phosphoric ester hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0048273 mitogen-activated protein kinase p38 binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0019899 enzyme binding; GO:0008047 enzyme activator activity; GO:0032403 protein complex binding; ","K04403","MAP3K7IP1; TAK1-binding protein 1","hsa04380 Osteoclast differentiation - Homo sapiens (human); hsa04620 Toll-like receptor signaling pathway - Homo sapiens (human); hsa05168 Herpes simplex infection - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); hsa05140 Leishmaniasis - Homo sapiens (human); hsa04668 TNF signaling pathway - Homo sapiens (human); hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human); hsa04010 MAPK signaling pathway - Homo sapiens (human); hsa05145 Toxoplasmosis - Homo sapiens (human); hsa04064 NF-kappa B signaling pathway - Homo sapiens (human); ","IPR001932; ","PPM-type phosphatase domain; \r"]
["Q15758","Neutral amino acid transporter B(0) OS=Homo sapiens OX=9606 GN=SLC1A5","SLC1A5",56.598,10.616,7.9,3,4,3,0.733,0.911,0.885,1.098,1.271,1.087,1.367,0.0208,"plasma membrane\r","GO:0044409 entry into host; GO:0032329 serine transport; GO:0034220 ion transmembrane transport; GO:0051806 entry into cell of other organism involved in symbiotic interaction; GO:0019058 viral life cycle; GO:0015807 L-amino acid transport; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0098656 anion transmembrane transport; GO:0051234 establishment of localization; GO:0006868 glutamine transport; GO:1902578 single-organism localization; GO:0006812 cation transport; GO:1903825 organic acid transmembrane transport; GO:0016032 viral process; GO:0015825 L-serine transport; GO:0006865 amino acid transport; GO:0044419 interspecies interaction between organisms; GO:0009987 cellular process; GO:0006860 extracellular amino acid transport; GO:0046718 viral entry into host cell; GO:0044765 single-organism transport; GO:1905039 carboxylic acid transmembrane transport; GO:0071702 organic substance transport; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0051701 interaction with host; GO:0046942 carboxylic acid transport; GO:0003333 amino acid transmembrane transport; GO:0015849 organic acid transport; GO:0051704 multi-organism process; GO:0006820 anion transport; GO:0006810 transport; GO:0055085 transmembrane transport; GO:0030260 entry into host cell; GO:0015711 organic anion transport; GO:0006858 extracellular transport; GO:0006811 ion transport; GO:0051828 entry into other organism involved in symbiotic interaction; GO:0051179 localization; GO:0015804 neutral amino acid transport; GO:0071705 nitrogen compound transport; ","GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031226 intrinsic component of plasma membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0042470 melanosome; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0048770 pigment granule; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005342 organic acid transmembrane transporter activity; GO:0022804 active transmembrane transporter activity; GO:0015291 secondary active transmembrane transporter activity; GO:1905361 L-serine transporter activity; GO:0015075 ion transmembrane transporter activity; GO:0015179 L-amino acid transmembrane transporter activity; GO:0015293 symporter activity; GO:0022889 serine transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0015186 L-glutamine transmembrane transporter activity; GO:0005515 protein binding; GO:0015194 L-serine transmembrane transporter activity; GO:0001618 virus receptor activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0015175 neutral amino acid transmembrane transporter activity; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0005488 binding; GO:0008514 organic anion transmembrane transporter activity; GO:0008324 cation transmembrane transporter activity; GO:0046943 carboxylic acid transmembrane transporter activity; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; GO:0008509 anion transmembrane transporter activity; GO:0015171 amino acid transmembrane transporter activity; ","K05616","SLC1A5; solute carrier family 1 (neutral amino acid transporter), member 5","hsa04974 Protein digestion and absorption - Homo sapiens (human); hsa05230 Central carbon metabolism in cancer - Homo sapiens (human); "]
["Q15814","Tubulin-specific chaperone C OS=Homo sapiens OX=9606 GN=TBCC","TBCC",39.248,20.608,4.3,1,1,1,0.874,1.11,1.02,0.923,1.053,1.025,0.999,0.979,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0032502 developmental process; GO:0034622 cellular macromolecular complex assembly; GO:0016043 cellular component organization; GO:0071822 protein complex subunit organization; GO:0007021 tubulin complex assembly; GO:0048869 cellular developmental process; GO:0044763 single-organism cellular process; GO:0032989 cellular component morphogenesis; GO:0044699 single-organism process; GO:0043933 macromolecular complex subunit organization; GO:0006457 protein folding; GO:0000902 cell morphogenesis; GO:0009653 anatomical structure morphogenesis; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0044767 single-organism developmental process; GO:0070271 protein complex biogenesis; GO:0009987 cellular process; GO:0048856 anatomical structure development; GO:0007023 post-chaperonin tubulin folding pathway; GO:0006461 protein complex assembly; GO:0043623 cellular protein complex assembly; GO:0071840 cellular component organization or biogenesis; ","GO:0005929 cilium; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0099513 polymeric cytoskeletal fiber; GO:0005874 microtubule; GO:0035869 ciliary transition zone; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0097730 non-motile cilium; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0097731 9+0 non-motile cilium; GO:0044422 organelle part; GO:0099081 supramolecular polymer; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0005856 cytoskeleton; GO:0032391 photoreceptor connecting cilium; GO:0044441 ciliary part; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0097733 photoreceptor cell cilium; GO:0097458 neuron part; GO:0044444 cytoplasmic part; ","GO:0008092 cytoskeletal protein binding; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0051087 chaperone binding; GO:0005488 binding; GO:0003924 GTPase activity; GO:0015631 tubulin binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0017111 nucleoside-triphosphatase activity; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; ",{"$nulls":3},"IPR006599; IPR016098; IPR031925; IPR017901; IPR012945; ","\"CARP motif; Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal; Tubulin-specific chaperone C, N-terminal; C-CAP/cofactor C-like domain; Tubulin binding cofactor C-like domain; \"\r"]
["Q15828","Cystatin-M OS=Homo sapiens OX=9606 GN=CST6","CST6",16.511,54.298,37.6,4,9,4,1.111,1.093,1.163,0.883,0.94,0.888,0.805,0.00136,"extracellular\r","GO:0050794 regulation of cellular process; GO:0010951 negative regulation of endopeptidase activity; GO:0060255 regulation of macromolecule metabolic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0051346 negative regulation of hydrolase activity; GO:0009653 anatomical structure morphogenesis; GO:0010466 negative regulation of peptidase activity; GO:0008544 epidermis development; GO:0032502 developmental process; GO:0052548 regulation of endopeptidase activity; GO:0045861 negative regulation of proteolysis; GO:0009888 tissue development; GO:0080090 regulation of primary metabolic process; GO:0030162 regulation of proteolysis; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0009892 negative regulation of metabolic process; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0051246 regulation of protein metabolic process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0065009 regulation of molecular function; GO:0051248 negative regulation of protein metabolic process; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0052547 regulation of peptidase activity; GO:0048856 anatomical structure development; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0001533 cornified envelope; GO:0044464 cell part; GO:0071944 cell periphery; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; GO:0005886 plasma membrane; ","GO:0061135 endopeptidase regulator activity; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0030234 enzyme regulator activity; GO:0004866 endopeptidase inhibitor activity; GO:0004869 cysteine-type endopeptidase inhibitor activity; GO:0030414 peptidase inhibitor activity; GO:0061134 peptidase regulator activity; ","K13902",null,null,"IPR000010; ","Cystatin domain; \r"]
["Q15843","NEDD8 OS=Homo sapiens OX=9606 GN=NEDD8","NEDD8",9.0714,10.767,17.3,2,3,2,1.021,1.086,1.031,0.961,0.966,1.008,0.935,0.0522,"cytoplasm\r","GO:0044700 single organism signaling; GO:0070646 protein modification by small protein removal; GO:0007166 cell surface receptor signaling pathway; GO:0071560 cellular response to transforming growth factor beta stimulus; GO:0044699 single-organism process; GO:0071363 cellular response to growth factor stimulus; GO:0044237 cellular metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0007154 cell communication; GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0009719 response to endogenous stimulus; GO:0070848 response to growth factor; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0031323 regulation of cellular metabolic process; GO:0023052 signaling; GO:0071559 response to transforming growth factor beta; GO:1901575 organic substance catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0030163 protein catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006464 cellular protein modification process; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0016579 protein deubiquitination; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0009653 anatomical structure morphogenesis; GO:0009889 regulation of biosynthetic process; GO:0044248 cellular catabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0006508 proteolysis; GO:0009987 cellular process; GO:0043632 modification-dependent macromolecule catabolic process; GO:0045116 protein neddylation; GO:0044265 cellular macromolecule catabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0019941 modification-dependent protein catabolic process; GO:0007179 transforming growth factor beta receptor signaling pathway; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0032446 protein modification by small protein conjugation; GO:0071495 cellular response to endogenous stimulus; GO:0009057 macromolecule catabolic process; GO:0051179 localization; GO:0043412 macromolecule modification; GO:0009056 catabolic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0031625 ubiquitin protein ligase binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0005488 binding; GO:0019899 enzyme binding; ","K12158",null,null,"IPR029071; IPR000626; ","Ubiquitin-related domain; Ubiquitin domain; \r"]
["Q15847","Adipogenesis regulatory factor OS=Homo sapiens OX=9606 GN=ADIRF","ADIRF",7.8547,88.886,80.3,5,12,5,1.155,1.129,1.146,0.906,0.869,0.847,0.764,2.02E-4,"cytoplasm\r","GO:0072718 response to cisplatin; GO:0097659 nucleic acid-templated transcription; GO:0048869 cellular developmental process; GO:0009891 positive regulation of biosynthetic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0009314 response to radiation; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0043170 macromolecule metabolic process; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0071214 cellular response to abiotic stimulus; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0051094 positive regulation of developmental process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0006725 cellular aromatic compound metabolic process; GO:0009628 response to abiotic stimulus; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0050896 response to stimulus; GO:0045597 positive regulation of cell differentiation; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0045600 positive regulation of fat cell differentiation; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0072719 cellular response to cisplatin; GO:0009059 macromolecule biosynthetic process; GO:0071478 cellular response to radiation; GO:2001023 regulation of response to drug; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0051254 positive regulation of RNA metabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0045598 regulation of fat cell differentiation; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044767 single-organism developmental process; GO:0031325 positive regulation of cellular metabolic process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0010467 gene expression; GO:0031328 positive regulation of cellular biosynthetic process; GO:0050793 regulation of developmental process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; "]
["Q15942","Zyxin OS=Homo sapiens OX=9606 GN=ZYX","ZYX",61.277,32.133,18.4,8,12,8,0.955,1.036,1.044,1.023,1.004,0.935,0.976,0.572,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0016043 cellular component organization; GO:0007166 cell surface receptor signaling pathway; GO:0071310 cellular response to organic substance; GO:0071560 cellular response to transforming growth factor beta stimulus; GO:0030038 contractile actin filament bundle assembly; GO:0007015 actin filament organization; GO:0044699 single-organism process; GO:0051017 actin filament bundle assembly; GO:0080134 regulation of response to stress; GO:0044764 multi-organism cellular process; GO:0071363 cellular response to growth factor stimulus; GO:0031347 regulation of defense response; GO:0050896 response to stimulus; GO:0022610 biological adhesion; GO:0030036 actin cytoskeleton organization; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0016032 viral process; GO:0007160 cell-matrix adhesion; GO:0007155 cell adhesion; GO:0009719 response to endogenous stimulus; GO:0070848 response to growth factor; GO:0007010 cytoskeleton organization; GO:0044419 interspecies interaction between organisms; GO:0009987 cellular process; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0070887 cellular response to chemical stimulus; GO:0031032 actomyosin structure organization; GO:0051716 cellular response to stimulus; GO:0007179 transforming growth factor beta receptor signaling pathway; GO:0044763 single-organism cellular process; GO:0032101 regulation of response to external stimulus; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0010033 response to organic substance; GO:0071559 response to transforming growth factor beta; GO:0023052 signaling; GO:0007229 integrin-mediated signaling pathway; GO:0051704 multi-organism process; GO:0061572 actin filament bundle organization; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0007267 cell-cell signaling; GO:0031589 cell-substrate adhesion; GO:0006996 organelle organization; GO:0071495 cellular response to endogenous stimulus; GO:0030029 actin filament-based process; GO:0048583 regulation of response to stimulus; GO:0050727 regulation of inflammatory response; GO:0097435 supramolecular fiber organization; GO:0043149 stress fiber assembly; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005913 cell-cell adherens junction; GO:0005623 cell; GO:0005911 cell-cell junction; GO:0044422 organelle part; GO:0032432 actin filament bundle; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0005912 adherens junction; GO:0001725 stress fiber; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0042641 actomyosin; GO:0005924 cell-substrate adherens junction; GO:0043229 intracellular organelle; GO:0031226 intrinsic component of plasma membrane; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0097517 contractile actin filament bundle; GO:0005829 cytosol; GO:0015629 actin cytoskeleton; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0046914 transition metal ion binding; GO:0005488 binding; GO:0043167 ion binding; GO:0003676 nucleic acid binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0008270 zinc ion binding; ","K06273","ZYX; zyxin","hsa04510 Focal adhesion - Homo sapiens (human); ","IPR001781; ","\"Zinc finger, LIM-type; \"\r"]
["Q16134","Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial OS=Homo sapiens OX=9606 GN=ETFDH","ETFDH",68.495,45.87,19.4,11,12,11,1.107,1.018,1.103,0.883,0.944,0.991,0.873,0.0344,"mitochondria\r","GO:0034440 lipid oxidation; GO:0044699 single-organism process; GO:0022904 respiratory electron transport chain; GO:0044255 cellular lipid metabolic process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0030258 lipid modification; GO:0006979 response to oxidative stress; GO:0044248 cellular catabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0009987 cellular process; GO:0006629 lipid metabolic process; GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase; GO:0016042 lipid catabolic process; GO:0019395 fatty acid oxidation; GO:0006950 response to stress; GO:0055114 oxidation-reduction process; GO:0044712 single-organism catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006635 fatty acid beta-oxidation; GO:0072329 monocarboxylic acid catabolic process; GO:0044282 small molecule catabolic process; GO:0006631 fatty acid metabolic process; GO:0044238 primary metabolic process; GO:0045333 cellular respiration; GO:0046395 carboxylic acid catabolic process; GO:1901575 organic substance catabolic process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0019752 carboxylic acid metabolic process; GO:0016054 organic acid catabolic process; GO:0022900 electron transport chain; GO:0044242 cellular lipid catabolic process; GO:0006082 organic acid metabolic process; GO:0009056 catabolic process; GO:0009062 fatty acid catabolic process; GO:0043436 oxoacid metabolic process; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0031305 integral component of mitochondrial inner membrane; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0045251 electron transfer flavoprotein complex; GO:0031304 intrinsic component of mitochondrial inner membrane; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:0031301 integral component of organelle membrane; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0019866 organelle inner membrane; GO:0017133 mitochondrial electron transfer flavoprotein complex; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005759 mitochondrial matrix; GO:0098573 intrinsic component of mitochondrial membrane; GO:0044429 mitochondrial part; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0016021 integral component of membrane; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031975 envelope; GO:0032592 integral component of mitochondrial membrane; GO:0043234 protein complex; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; GO:0031300 intrinsic component of organelle membrane; ","GO:0004174 electron-transferring-flavoprotein dehydrogenase activity; GO:0043783 oxidoreductase activity, oxidizing metal ions with flavin as acceptor; GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors; GO:0016722 oxidoreductase activity, oxidizing metal ions; GO:1901265 nucleoside phosphate binding; GO:0050660 flavin adenine dinucleotide binding; GO:0043167 ion binding; GO:0000166 nucleotide binding; GO:0051539 4 iron, 4 sulfur cluster binding; GO:0048037 cofactor binding; GO:0016491 oxidoreductase activity; GO:0009055 electron carrier activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016649 oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor; GO:0003824 catalytic activity; GO:0048039 ubiquinone binding; GO:0051536 iron-sulfur cluster binding; GO:0005488 binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0048038 quinone binding; GO:0051540 metal cluster binding; GO:0036094 small molecule binding; GO:0050662 coenzyme binding; ","K00311",null,null,"IPR017896; IPR023753; ","\"4Fe-4S ferredoxin-type, iron-sulphur binding domain; FAD/NAD(P)-binding domain; \"\r"]
["Q16186","Proteasomal ubiquitin receptor ADRM1 OS=Homo sapiens OX=9606 GN=ADRM1","ADRM1",42.153,33.023,12.3,5,12,5,0.886,0.917,0.88,0.97,1.087,1.131,1.188,0.0234,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0070646 protein modification by small protein removal; GO:0032270 positive regulation of cellular protein metabolic process; GO:0097659 nucleic acid-templated transcription; GO:0009058 biosynthetic process; GO:0006354 DNA-templated transcription, elongation; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0009893 positive regulation of metabolic process; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0044093 positive regulation of molecular function; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0052548 regulation of endopeptidase activity; GO:0018130 heterocycle biosynthetic process; GO:0071822 protein complex subunit organization; GO:0010950 positive regulation of endopeptidase activity; GO:0080090 regulation of primary metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0032774 RNA biosynthetic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0031323 regulation of cellular metabolic process; GO:0016070 RNA metabolic process; GO:1901575 organic substance catabolic process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0051336 regulation of hydrolase activity; GO:0006351 transcription, DNA-templated; GO:0030163 protein catabolic process; GO:0050790 regulation of catalytic activity; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0065009 regulation of molecular function; GO:0006464 cellular protein modification process; GO:0036211 protein modification process; GO:0052547 regulation of peptidase activity; GO:0070271 protein complex biogenesis; GO:1901362 organic cyclic compound biosynthetic process; GO:0010952 positive regulation of peptidase activity; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0043248 proteasome assembly; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0044267 cellular protein metabolic process; GO:0016579 protein deubiquitination; GO:0071704 organic substance metabolic process; GO:0045862 positive regulation of proteolysis; GO:0046483 heterocycle metabolic process; GO:0051345 positive regulation of hydrolase activity; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0044248 cellular catabolic process; GO:0006508 proteolysis; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0043623 cellular protein complex assembly; GO:0043632 modification-dependent macromolecule catabolic process; GO:0034622 cellular macromolecular complex assembly; GO:0044265 cellular macromolecule catabolic process; GO:0019941 modification-dependent protein catabolic process; GO:0006368 transcription elongation from RNA polymerase II promoter; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0043085 positive regulation of catalytic activity; GO:0043933 macromolecular complex subunit organization; GO:0051247 positive regulation of protein metabolic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0051246 regulation of protein metabolic process; GO:0009057 macromolecule catabolic process; GO:0006366 transcription from RNA polymerase II promoter; GO:0031325 positive regulation of cellular metabolic process; GO:0010467 gene expression; GO:0043412 macromolecule modification; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0071944 cell periphery; GO:0005838 proteasome regulatory particle; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0044422 organelle part; GO:1905369 endopeptidase complex; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0022624 proteasome accessory complex; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:1905368 peptidase complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0031226 intrinsic component of plasma membrane; GO:0000502 proteasome complex; GO:0008541 proteasome regulatory particle, lid subcomplex; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0044877 macromolecular complex binding; GO:0061134 peptidase regulator activity; GO:0016504 peptidase activator activity; GO:0061133 endopeptidase activator activity; GO:0005515 protein binding; GO:0070628 proteasome binding; GO:0098772 molecular function regulator; GO:0032182 ubiquitin-like protein binding; GO:0002020 protease binding; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0043130 ubiquitin binding; GO:0061135 endopeptidase regulator activity; GO:0008047 enzyme activator activity; GO:0019899 enzyme binding; GO:0032403 protein complex binding; ",{"$nulls":3},"IPR032368; ","UCH-binding domain; \r"]
["Q16254","Transcription factor E2F4 OS=Homo sapiens OX=9606 GN=E2F4","E2F4",43.96,2.0625,1.9,1,1,1,0.963,0.977,0.96,0.975,1.098,1.03,1.07,0.196,"nucleus\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:1902807 negative regulation of cell cycle G1/S phase transition; GO:0065008 regulation of biological quality; GO:0097659 nucleic acid-templated transcription; GO:0009891 positive regulation of biosynthetic process; GO:0060271 cilium assembly; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0044782 cilium organization; GO:0072431 signal transduction involved in mitotic G1 DNA damage checkpoint; GO:1902403 signal transduction involved in mitotic DNA integrity checkpoint; GO:0008152 metabolic process; GO:0032535 regulation of cellular component size; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0044770 cell cycle phase transition; GO:0043170 macromolecule metabolic process; GO:0090068 positive regulation of cell cycle process; GO:0051716 cellular response to stimulus; GO:0000278 mitotic cell cycle; GO:0018130 heterocycle biosynthetic process; GO:0002064 epithelial cell development; GO:0044773 mitotic DNA damage checkpoint; GO:0080090 regulation of primary metabolic process; GO:2000134 negative regulation of G1/S transition of mitotic cell cycle; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044763 single-organism cellular process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0010948 negative regulation of cell cycle process; GO:0072413 signal transduction involved in mitotic cell cycle checkpoint; GO:1902400 intracellular signal transduction involved in G1 DNA damage checkpoint; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0098534 centriole assembly; GO:0009887 animal organ morphogenesis; GO:0010604 positive regulation of macromolecule metabolic process; GO:0003013 circulatory system process; GO:1901362 organic cyclic compound biosynthetic process; GO:0030855 epithelial cell differentiation; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0044707 single-multicellular organism process; GO:0007346 regulation of mitotic cell cycle; GO:0042127 regulation of cell proliferation; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0030330 DNA damage response, signal transduction by p53 class mediator; GO:0009653 anatomical structure morphogenesis; GO:0006884 cell volume homeostasis; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:1902402 signal transduction involved in mitotic DNA damage checkpoint; GO:1901987 regulation of cell cycle phase transition; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0044819 mitotic G1/S transition checkpoint; GO:0007093 mitotic cell cycle checkpoint; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0007275 multicellular organism development; GO:0045787 positive regulation of cell cycle; GO:0044772 mitotic cell cycle phase transition; GO:0051254 positive regulation of RNA metabolic process; GO:0006950 response to stress; GO:0048731 system development; GO:0044458 motile cilium assembly; GO:0072331 signal transduction by p53 class mediator; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle; GO:0044238 primary metabolic process; GO:0007017 microtubule-based process; GO:1901576 organic substance biosynthetic process; GO:0006974 cellular response to DNA damage stimulus; GO:0030031 cell projection assembly; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:2000045 regulation of G1/S transition of mitotic cell cycle; GO:0048869 cellular developmental process; GO:0044783 G1 DNA damage checkpoint; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0045930 negative regulation of mitotic cell cycle; GO:0000077 DNA damage checkpoint; GO:0007154 cell communication; GO:0044774 mitotic DNA integrity checkpoint; GO:1901991 negative regulation of mitotic cell cycle phase transition; GO:0022607 cellular component assembly; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:1902806 regulation of cell cycle G1/S phase transition; GO:0000075 cell cycle checkpoint; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0051726 regulation of cell cycle; GO:0031571 mitotic G1 DNA damage checkpoint; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0060429 epithelium development; GO:0009888 tissue development; GO:0031326 regulation of cellular biosynthetic process; GO:0031570 DNA integrity checkpoint; GO:0019725 cellular homeostasis; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:1903251 multi-ciliated epithelial cell differentiation; GO:0023052 signaling; GO:0016070 RNA metabolic process; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0030030 cell projection organization; GO:0006351 transcription, DNA-templated; GO:0019222 regulation of metabolic process; GO:0048856 anatomical structure development; GO:0072401 signal transduction involved in DNA integrity checkpoint; GO:0016043 cellular component organization; GO:0045786 negative regulation of cell cycle; GO:0072395 signal transduction involved in cell cycle checkpoint; GO:0006725 cellular aromatic compound metabolic process; GO:1901988 negative regulation of cell cycle phase transition; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:0008361 regulation of cell size; GO:0070925 organelle assembly; GO:0008015 blood circulation; GO:0042770 signal transduction in response to DNA damage; GO:0034641 cellular nitrogen compound metabolic process; GO:0000082 G1/S transition of mitotic cell cycle; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0071156 regulation of cell cycle arrest; GO:0006355 regulation of transcription, DNA-templated; GO:0003008 system process; GO:0072422 signal transduction involved in DNA damage checkpoint; GO:0035556 intracellular signal transduction; GO:0044843 cell cycle G1/S phase transition; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044767 single-organism developmental process; GO:0006366 transcription from RNA polymerase II promoter; GO:0071158 positive regulation of cell cycle arrest; GO:0090066 regulation of anatomical structure size; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0010467 gene expression; GO:0022402 cell cycle process; GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; GO:0007049 cell cycle; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005667 transcription factor complex; GO:0005623 cell; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0000785 chromatin; GO:0044454 nuclear chromosome part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005694 chromosome; GO:0000790 nuclear chromatin; GO:0000228 nuclear chromosome; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0003677 DNA binding; GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding; GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding; GO:0000976 transcription regulatory region sequence-specific DNA binding; GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding; GO:0003690 double-stranded DNA binding; GO:1990837 sequence-specific double-stranded DNA binding; GO:0001012 RNA polymerase II regulatory region DNA binding; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:0003682 chromatin binding; GO:0043565 sequence-specific DNA binding; GO:1990841 promoter-specific chromatin binding; GO:0000987 core promoter proximal region sequence-specific DNA binding; GO:0003700 transcription factor activity, sequence-specific DNA binding; GO:1901363 heterocyclic compound binding; GO:0000975 regulatory region DNA binding; GO:0097159 organic cyclic compound binding; GO:0001159 core promoter proximal region DNA binding; GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding; GO:0001067 regulatory region nucleic acid binding; GO:0044212 transcription regulatory region DNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0001071 nucleic acid binding transcription factor activity; GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding; GO:0019904 protein domain specific binding; GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding; GO:0008134 transcription factor binding; ","K04682","E2F4_5; transcription factor E2F4/5","hsa04350 TGF-beta signaling pathway - Homo sapiens (human); hsa04110 Cell cycle - Homo sapiens (human); hsa04218 Cellular senescence - Homo sapiens (human); ","IPR003316; IPR011991; IPR032198; ","\"E2F/DP family, winged-helix DNA-binding domain; Winged helix-turn-helix DNA-binding domain; E2F transcription factor, CC-MB domain; \"\r"]
["Q16527","Cysteine and glycine-rich protein 2 OS=Homo sapiens OX=9606 GN=CSRP2","CSRP2",20.954,17.266,20.7,3,3,3,1.037,1.079,1.089,0.986,0.855,0.973,0.878,0.0511,"nucleus\r","GO:0032502 developmental process; GO:0044707 single-multicellular organism process; GO:0030154 cell differentiation; GO:0044767 single-organism developmental process; GO:0048869 cellular developmental process; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0007275 multicellular organism development; GO:0048856 anatomical structure development; GO:0032501 multicellular organismal process; GO:0009987 cellular process; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0005925 focal adhesion; GO:0030054 cell junction; GO:0044464 cell part; GO:0005622 intracellular; GO:0005912 adherens junction; GO:0070161 anchoring junction; GO:0030055 cell-substrate junction; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0005924 cell-substrate adherens junction; ","GO:0046914 transition metal ion binding; GO:0005488 binding; GO:0043167 ion binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0008270 zinc ion binding; ","K09377",null,null,"IPR001781; ","\"Zinc finger, LIM-type; \"\r"]
["Q16537","Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform OS=Homo sapiens OX=9606 GN=PPP2R5E","PPP2R5E",54.699,8.8084,4.7,2,3,2,1.282,0.917,0.969,0.894,0.979,0.975,0.899,0.423,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0051716 cellular response to stimulus; GO:0007165 signal transduction; GO:0050789 regulation of biological process; GO:0007154 cell communication; GO:0050790 regulation of catalytic activity; GO:0065009 regulation of molecular function; GO:0044699 single-organism process; GO:0023052 signaling; GO:0050896 response to stimulus; GO:0009987 cellular process; GO:0065007 biological regulation; ","GO:1902494 catalytic complex; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0008287 protein serine/threonine phosphatase complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:1903293 phosphatase complex; GO:0000159 protein phosphatase type 2A complex; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0030234 enzyme regulator activity; GO:0019888 protein phosphatase regulator activity; GO:0019208 phosphatase regulator activity; GO:0005488 binding; ","K11584","PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'","hsa04728 Dopaminergic synapse - Homo sapiens (human); hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human); hsa04071 Sphingolipid signaling pathway - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa04152 AMPK signaling pathway - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa03015 mRNA surveillance pathway - Homo sapiens (human); hsa04114 Oocyte meiosis - Homo sapiens (human); ","IPR011989; IPR016024; ","Armadillo-like helical; Armadillo-type fold; \r"]
["Q16555","Dihydropyrimidinase-related protein 2 OS=Homo sapiens OX=9606 GN=DPYSL2","DPYSL2",62.293,247.28,47.7,20,49,17,1.07,1.043,1.073,0.948,0.913,0.965,0.887,0.003,"cyto_nucl\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0007420 brain development; GO:0048869 cellular developmental process; GO:0048666 neuron development; GO:0032989 cellular component morphogenesis; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:0001558 regulation of cell growth; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0032990 cell part morphogenesis; GO:0032535 regulation of cellular component size; GO:0048858 cell projection morphogenesis; GO:0060322 head development; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0048812 neuron projection morphogenesis; GO:0023052 signaling; GO:0006935 chemotaxis; GO:0032501 multicellular organismal process; GO:0000902 cell morphogenesis; GO:0006810 transport; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0045664 regulation of neuron differentiation; GO:0030030 cell projection organization; GO:0007417 central nervous system development; GO:0042330 taxis; GO:0040011 locomotion; GO:0048856 anatomical structure development; GO:0010975 regulation of neuron projection development; GO:2000026 regulation of multicellular organismal development; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0040008 regulation of growth; GO:0006725 cellular aromatic compound metabolic process; GO:0031344 regulation of cell projection organization; GO:0048638 regulation of developmental growth; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0007411 axon guidance; GO:0051239 regulation of multicellular organismal process; GO:0071704 organic substance metabolic process; GO:0000904 cell morphogenesis involved in differentiation; GO:0009653 anatomical structure morphogenesis; GO:0030154 cell differentiation; GO:0008361 regulation of cell size; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0007409 axonogenesis; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:0006897 endocytosis; GO:0031175 neuron projection development; GO:0050770 regulation of axonogenesis; GO:0061564 axon development; GO:0030182 neuron differentiation; GO:0030516 regulation of axon extension; GO:0097485 neuron projection guidance; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0061387 regulation of extent of cell growth; GO:0090066 regulation of anatomical structure size; GO:0006928 movement of cell or subcellular component; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0022604 regulation of cell morphogenesis; GO:0050793 regulation of developmental process; GO:0050767 regulation of neurogenesis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0008092 cytoskeletal protein binding; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0008017 microtubule binding; GO:0005488 binding; GO:0015631 tubulin binding; GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides; GO:0004157 dihydropyrimidinase activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; ","K07528","DPYSL2; dihydropyrimidinase-like 2","hsa04360 Axon guidance - Homo sapiens (human); ","IPR032466; IPR006680; IPR011059; ","\"Metal-dependent hydrolase; Amidohydrolase-related; Metal-dependent hydrolase, composite domain; \"\r"]
["Q16576","Histone-binding protein RBBP7 OS=Homo sapiens OX=9606 GN=RBBP7","RBBP7",47.82,6.847,18.4,8,13,2,0.907,0.898,0.864,1.119,1.065,1.055,1.214,0.0012,"cyto_nucl\r","GO:0044085 cellular component biogenesis; GO:0097659 nucleic acid-templated transcription; GO:0044237 cellular metabolic process; GO:0001558 regulation of cell growth; GO:0008152 metabolic process; GO:0006334 nucleosome assembly; GO:0034724 DNA replication-independent nucleosome organization; GO:0065003 macromolecular complex assembly; GO:0009408 response to heat; GO:0048545 response to steroid hormone; GO:0009719 response to endogenous stimulus; GO:0019538 protein metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0043170 macromolecule metabolic process; GO:0006476 protein deacetylation; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0034508 centromere complex assembly; GO:0000122 negative regulation of transcription from RNA polymerase II promoter; GO:0032774 RNA biosynthetic process; GO:0043044 ATP-dependent chromatin remodeling; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0065004 protein-DNA complex assembly; GO:1903506 regulation of nucleic acid-templated transcription; GO:0035601 protein deacylation; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0034080 CENP-A containing nucleosome assembly; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0034728 nucleosome organization; GO:0044707 single-multicellular organism process; GO:0033554 cellular response to stress; GO:0006338 chromatin remodeling; GO:0006260 DNA replication; GO:0043486 histone exchange; GO:0006259 DNA metabolic process; GO:0009628 response to abiotic stimulus; GO:0016570 histone modification; GO:0044267 cellular protein metabolic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0045892 negative regulation of transcription, DNA-templated; GO:0006323 DNA packaging; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0016569 covalent chromatin modification; GO:0007275 multicellular organism development; GO:0006336 DNA replication-independent nucleosome assembly; GO:0009966 regulation of signal transduction; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:1902531 regulation of intracellular signal transduction; GO:0006950 response to stress; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0008283 cell proliferation; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0009890 negative regulation of biosynthetic process; GO:0031055 chromatin remodeling at centromere; GO:0051276 chromosome organization; GO:0006996 organelle organization; GO:0043412 macromolecule modification; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0070370 cellular heat acclimation; GO:0051253 negative regulation of RNA metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0010646 regulation of cell communication; GO:0022607 cellular component assembly; GO:0031497 chromatin assembly; GO:0098732 macromolecule deacylation; GO:0071824 protein-DNA complex subunit organization; GO:0071103 DNA conformation change; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0045926 negative regulation of growth; GO:0006333 chromatin assembly or disassembly; GO:0031326 regulation of cellular biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0030308 negative regulation of cell growth; GO:0016070 RNA metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0034605 cellular response to heat; GO:1902679 negative regulation of RNA biosynthetic process; GO:0019222 regulation of metabolic process; GO:0045814 negative regulation of gene expression, epigenetic; GO:0006325 chromatin organization; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0016043 cellular component organization; GO:0040008 regulation of growth; GO:0006725 cellular aromatic compound metabolic process; GO:0061641 CENP-A containing chromatin organization; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0033993 response to lipid; GO:0009266 response to temperature stimulus; GO:1901796 regulation of signal transduction by p53 class mediator; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0016575 histone deacetylation; GO:0034622 cellular macromolecular complex assembly; GO:0010286 heat acclimation; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0040029 regulation of gene expression, epigenetic; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0044767 single-organism developmental process; GO:0010467 gene expression; GO:0031327 negative regulation of cellular biosynthetic process; GO:0051128 regulation of cellular component organization; GO:0009725 response to hormone; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0017053 transcriptional repressor complex; GO:0044424 intracellular part; GO:0070603 SWI/SNF superfamily-type complex; GO:0005623 cell; GO:0000118 histone deacetylase complex; GO:0044422 organelle part; GO:0090568 nuclear transcriptional repressor complex; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0090545 CHD-type complex; GO:0016581 NuRD complex; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0035097 histone methyltransferase complex; GO:1990234 transferase complex; GO:0005829 cytosol; GO:0034708 methyltransferase complex; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0035098 ESC/E(Z) complex; GO:0031519 PcG protein complex; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0004407 histone deacetylase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0033558 protein deacetylase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0019213 deacetylase activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; ","K11659",null,null,"IPR022052; IPR017986; IPR015943; ","\"Histone-binding protein RBBP4, N-terminal; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain; \"\r"]
["Q16630","Cleavage and polyadenylation specificity factor subunit 6 OS=Homo sapiens OX=9606 GN=CPSF6","CPSF6",59.209,32.373,12.7,6,10,6,0.976,0.949,0.925,1.044,1.025,1.086,1.107,0.0116,"nucleus\r","GO:0031123 RNA 3'-end processing; GO:0044085 cellular component biogenesis; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0031124 mRNA 3'-end processing; GO:0006378 mRNA polyadenylation; GO:0044237 cellular metabolic process; GO:0051259 protein oligomerization; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0051262 protein tetramerization; GO:0022607 cellular component assembly; GO:0006139 nucleobase-containing compound metabolic process; GO:0065003 macromolecular complex assembly; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0006396 RNA processing; GO:0071822 protein complex subunit organization; GO:0043631 RNA polyadenylation; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0044238 primary metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:0090304 nucleic acid metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0070271 protein complex biogenesis; GO:0016071 mRNA metabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044446 intracellular organelle part; GO:0042382 paraspeckles; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0005849 mRNA cleavage factor complex; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0044464 cell part; GO:0005622 intracellular; GO:1990904 ribonucleoprotein complex; GO:0043234 protein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003729 mRNA binding; GO:0003723 RNA binding; GO:1901265 nucleoside phosphate binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0036094 small molecule binding; ","K14398","CPSF6_7; cleavage and polyadenylation specificity factor subunit 6/7","hsa03015 mRNA surveillance pathway - Homo sapiens (human); ","IPR000504; IPR012677; ","RNA recognition motif domain; Nucleotide-binding alpha-beta plait domain; \r"]
["Q16643","Drebrin OS=Homo sapiens OX=9606 GN=DBN1","DBN1",71.428,98.796,23,13,13,13,1.11,1.122,1.126,0.919,0.855,0.879,0.79,0.000384,"nucleus\r","GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0065008 regulation of biological quality; GO:0023051 regulation of signaling; GO:0048869 cellular developmental process; GO:0007015 actin filament organization; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0031344 regulation of cell projection organization; GO:0051239 regulation of multicellular organismal process; GO:0061351 neural precursor cell proliferation; GO:0030036 actin cytoskeleton organization; GO:0030154 cell differentiation; GO:0010646 regulation of cell communication; GO:1902578 single-organism localization; GO:0007154 cell communication; GO:0051235 maintenance of location; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0034613 cellular protein localization; GO:0051651 maintenance of location in cell; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0048167 regulation of synaptic plasticity; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0010644 cell communication by electrical coupling; GO:0032507 maintenance of protein location in cell; GO:0045185 maintenance of protein location; GO:0048731 system development; GO:0048699 generation of neurons; GO:0051960 regulation of nervous system development; GO:0060284 regulation of cell development; GO:0050804 modulation of synaptic transmission; GO:0044763 single-organism cellular process; GO:0008283 cell proliferation; GO:0048168 regulation of neuronal synaptic plasticity; GO:0032501 multicellular organismal process; GO:0051641 cellular localization; GO:1902589 single-organism organelle organization; GO:0070727 cellular macromolecule localization; GO:0050789 regulation of biological process; GO:0045664 regulation of neuron differentiation; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0030029 actin filament-based process; GO:0050773 regulation of dendrite development; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0097435 supramolecular fiber organization; GO:0048856 anatomical structure development; GO:0010643 cell communication by chemical coupling; GO:0010975 regulation of neuron projection development; GO:0050767 regulation of neurogenesis; GO:2000026 regulation of multicellular organismal development; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0030425 dendrite; GO:0005938 cell cortex; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0099568 cytoplasmic region; GO:0030426 growth cone; GO:0044424 intracellular part; GO:0005911 cell-cell junction; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0044464 cell part; GO:0005622 intracellular; GO:0043005 neuron projection; GO:0042641 actomyosin; GO:0097458 neuron part; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0005921 gap junction; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0030427 site of polarized growth; GO:0044463 cell projection part; GO:0015629 actin cytoskeleton; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0044444 cytoplasmic part; ","GO:0050839 cell adhesion molecule binding; GO:0008092 cytoskeletal protein binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0003779 actin binding; GO:0005522 profilin binding; GO:0005515 protein binding; ",{"$nulls":3},"IPR029006; IPR002108; ","ADF-H/Gelsolin-like domain; Actin-depolymerising factor homology domain; \r"]
["Q16647","Prostacyclin synthase OS=Homo sapiens OX=9606 GN=PTGIS","PTGIS",57.103,92.357,14,5,10,5,1.135,1.072,1.095,0.975,0.924,0.856,0.834,0.0116,"extracellular\r","GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0019362 pyridine nucleotide metabolic process; GO:0045428 regulation of nitric oxide biosynthetic process; GO:0022414 reproductive process; GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway; GO:0007566 embryo implantation; GO:0035358 regulation of peroxisome proliferator activated receptor signaling pathway; GO:0044255 cellular lipid metabolic process; GO:0070555 response to interleukin-1; GO:0031347 regulation of defense response; GO:0071345 cellular response to cytokine stimulus; GO:0044237 cellular metabolic process; GO:0032088 negative regulation of NF-kappaB transcription factor activity; GO:0008610 lipid biosynthetic process; GO:0072525 pyridine-containing compound biosynthetic process; GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway; GO:0046697 decidualization; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0044706 multi-multicellular organism process; GO:0044702 single organism reproductive process; GO:0032102 negative regulation of response to external stimulus; GO:1904018 positive regulation of vasculature development; GO:0032787 monocarboxylic acid metabolic process; GO:0009108 coenzyme biosynthetic process; GO:0006690 icosanoid metabolic process; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0003006 developmental process involved in reproduction; GO:0080090 regulation of primary metabolic process; GO:0046457 prostanoid biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006732 coenzyme metabolic process; GO:0019359 nicotinamide nucleotide biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0090407 organophosphate biosynthetic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0019674 NAD metabolic process; GO:0051090 regulation of sequence-specific DNA binding transcription factor activity; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:0045765 regulation of angiogenesis; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0048609 multicellular organismal reproductive process; GO:0051094 positive regulation of developmental process; GO:1901362 organic cyclic compound biosynthetic process; GO:0043068 positive regulation of programmed cell death; GO:0043436 oxoacid metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0000003 reproduction; GO:0033559 unsaturated fatty acid metabolic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0044707 single-multicellular organism process; GO:0060135 maternal process involved in female pregnancy; GO:0019369 arachidonic acid metabolic process; GO:0097190 apoptotic signaling pathway; GO:0046496 nicotinamide nucleotide metabolic process; GO:0001890 placenta development; GO:0009628 response to abiotic stimulus; GO:0050728 negative regulation of inflammatory response; GO:0043067 regulation of programmed cell death; GO:0071354 cellular response to interleukin-6; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:0048519 negative regulation of biological process; GO:1904406 negative regulation of nitric oxide metabolic process; GO:0051239 regulation of multicellular organismal process; GO:0001516 prostaglandin biosynthetic process; GO:0007565 female pregnancy; GO:0046483 heterocycle metabolic process; GO:0045019 negative regulation of nitric oxide biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0070482 response to oxygen levels; GO:0051171 regulation of nitrogen compound metabolic process; GO:2000378 negative regulation of reactive oxygen species metabolic process; GO:0007275 multicellular organism development; GO:0061458 reproductive system development; GO:0009966 regulation of signal transduction; GO:0071456 cellular response to hypoxia; GO:0006950 response to stress; GO:0044711 single-organism biosynthetic process; GO:0048731 system development; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901570 fatty acid derivative biosynthetic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0032101 regulation of response to external stimulus; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009435 NAD biosynthetic process; GO:1903427 negative regulation of reactive oxygen species biosynthetic process; GO:0009890 negative regulation of biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0001676 long-chain fatty acid metabolic process; GO:0044283 small molecule biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0036293 response to decreased oxygen levels; GO:0012501 programmed cell death; GO:0048584 positive regulation of response to stimulus; GO:0050793 regulation of developmental process; GO:0072330 monocarboxylic acid biosynthetic process; GO:1901564 organonitrogen compound metabolic process; GO:0051188 cofactor biosynthetic process; GO:0016053 organic acid biosynthetic process; GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity; GO:0009117 nucleotide metabolic process; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:1901568 fatty acid derivative metabolic process; GO:0009058 biosynthetic process; GO:0019363 pyridine nucleotide biosynthetic process; GO:0072524 pyridine-containing compound metabolic process; GO:1900119 positive regulation of execution phase of apoptosis; GO:0006796 phosphate-containing compound metabolic process; GO:0001893 maternal placenta development; GO:2001141 regulation of RNA biosynthetic process; GO:0046456 icosanoid biosynthetic process; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0006753 nucleoside phosphate metabolic process; GO:0006915 apoptotic process; GO:0070887 cellular response to chemical stimulus; GO:0006629 lipid metabolic process; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0009888 tissue development; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0034097 response to cytokine; GO:0031326 regulation of cellular biosynthetic process; GO:0055114 oxidation-reduction process; GO:1900117 regulation of execution phase of apoptosis; GO:0048608 reproductive structure development; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0006636 unsaturated fatty acid biosynthetic process; GO:0023052 signaling; GO:0006633 fatty acid biosynthetic process; GO:0051186 cofactor metabolic process; GO:0010942 positive regulation of cell death; GO:0046394 carboxylic acid biosynthetic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0006693 prostaglandin metabolic process; GO:0006082 organic acid metabolic process; GO:2000377 regulation of reactive oxygen species metabolic process; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0019371 cyclooxygenase pathway; GO:0009165 nucleotide biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0043065 positive regulation of apoptotic process; GO:0071347 cellular response to interleukin-1; GO:0031324 negative regulation of cellular metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:0045766 positive regulation of angiogenesis; GO:0071704 organic substance metabolic process; GO:0023056 positive regulation of signaling; GO:0001666 response to hypoxia; GO:0034641 cellular nitrogen compound metabolic process; GO:0010647 positive regulation of cell communication; GO:0071453 cellular response to oxygen levels; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0031348 negative regulation of defense response; GO:0006355 regulation of transcription, DNA-templated; GO:1903426 regulation of reactive oxygen species biosynthetic process; GO:0006692 prostanoid metabolic process; GO:1901342 regulation of vasculature development; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0006631 fatty acid metabolic process; GO:0048585 negative regulation of response to stimulus; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0032504 multicellular organism reproduction; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0070741 response to interleukin-6; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0044703 multi-organism reproductive process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0019752 carboxylic acid metabolic process; GO:0050727 regulation of inflammatory response; GO:0031327 negative regulation of cellular biosynthetic process; GO:0009967 positive regulation of signal transduction; GO:0036294 cellular response to decreased oxygen levels; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0098857 membrane microdomain; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0098590 plasma membrane region; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0098589 membrane region; GO:0045121 membrane raft; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005901 caveola; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0044432 endoplasmic reticulum part; GO:0044853 plasma membrane raft; GO:0044444 cytoplasmic part; ","GO:0005506 iron ion binding; GO:0008116 prostaglandin-I synthase activity; GO:0043167 ion binding; GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; GO:0005515 protein binding; GO:0016491 oxidoreductase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0020037 heme binding; GO:0016853 isomerase activity; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0016860 intramolecular oxidoreductase activity; GO:0046906 tetrapyrrole binding; GO:0004497 monooxygenase activity; ","K01831","PTGIS; prostacyclin synthase [EC:5.3.99.4]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00590 Arachidonic acid metabolism - Homo sapiens (human); "]
["Q16698","2,4-dienoyl-CoA reductase, mitochondrial OS=Homo sapiens OX=9606 GN=DECR1","DECR1",36.067,99.24,40.9,12,25,12,1.029,1.047,1.055,0.92,0.945,0.978,0.908,0.00724,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:0034440 lipid oxidation; GO:0016043 cellular component organization; GO:0051260 protein homooligomerization; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0051259 protein oligomerization; GO:0051289 protein homotetramerization; GO:0008152 metabolic process; GO:0051262 protein tetramerization; GO:0022607 cellular component assembly; GO:0030258 lipid modification; GO:0065003 macromolecular complex assembly; GO:0032787 monocarboxylic acid metabolic process; GO:0044248 cellular catabolic process; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0006629 lipid metabolic process; GO:0016042 lipid catabolic process; GO:0019395 fatty acid oxidation; GO:0071822 protein complex subunit organization; GO:0055114 oxidation-reduction process; GO:0044712 single-organism catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0072329 monocarboxylic acid catabolic process; GO:0006635 fatty acid beta-oxidation; GO:0044282 small molecule catabolic process; GO:0006631 fatty acid metabolic process; GO:0044238 primary metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0046395 carboxylic acid catabolic process; GO:1901575 organic substance catabolic process; GO:0044710 single-organism metabolic process; GO:0016054 organic acid catabolic process; GO:0019752 carboxylic acid metabolic process; GO:0044242 cellular lipid catabolic process; GO:0006082 organic acid metabolic process; GO:0070271 protein complex biogenesis; GO:0009056 catabolic process; GO:0009062 fatty acid catabolic process; GO:0043436 oxoacid metabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:1901265 nucleoside phosphate binding; GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity; GO:0070402 NADPH binding; GO:0043167 ion binding; GO:0000166 nucleotide binding; GO:0048037 cofactor binding; GO:0016491 oxidoreductase activity; GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0050661 NADP binding; GO:0043168 anion binding; GO:0036094 small molecule binding; GO:0050662 coenzyme binding; ","K13236",null,null,"IPR016040; ","NAD(P)-binding domain; \r"]
["Q16719","Kynureninase OS=Homo sapiens OX=9606 GN=KYNU","KYNU",52.351,4.6895,4.7,2,2,2,0.541,0.731,0.648,1.272,1.484,1.284,2.104,1.74E-3,"cytoplasm\r","GO:0051188 cofactor biosynthetic process; GO:1901606 alpha-amino acid catabolic process; GO:0019362 pyridine nucleotide metabolic process; GO:0016053 organic acid biosynthetic process; GO:0042182 ketone catabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0019363 pyridine nucleotide biosynthetic process; GO:0034516 response to vitamin B6; GO:0072524 pyridine-containing compound metabolic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0072525 pyridine-containing compound biosynthetic process; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0006569 tryptophan catabolic process; GO:0042180 cellular ketone metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0006586 indolalkylamine metabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0009719 response to endogenous stimulus; GO:1901361 organic cyclic compound catabolic process; GO:0009108 coenzyme biosynthetic process; GO:0033273 response to vitamin; GO:0044106 cellular amine metabolic process; GO:0006790 sulfur compound metabolic process; GO:0009072 aromatic amino acid family metabolic process; GO:0014070 response to organic cyclic compound; GO:0018130 heterocycle biosynthetic process; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0034097 response to cytokine; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0019359 nicotinamide nucleotide biosynthetic process; GO:0006732 coenzyme metabolic process; GO:0006084 acetyl-CoA metabolic process; GO:0051186 cofactor metabolic process; GO:0090407 organophosphate biosynthetic process; GO:0046395 carboxylic acid catabolic process; GO:0043650 dicarboxylic acid biosynthetic process; GO:0019439 aromatic compound catabolic process; GO:1901575 organic substance catabolic process; GO:0046394 carboxylic acid biosynthetic process; GO:0010243 response to organonitrogen compound; GO:0042221 response to chemical; GO:0019674 NAD metabolic process; GO:0044710 single-organism metabolic process; GO:0009310 amine catabolic process; GO:1901698 response to nitrogen compound; GO:0009063 cellular amino acid catabolic process; GO:0006952 defense response; GO:0006082 organic acid metabolic process; GO:0019441 tryptophan catabolic process to kynurenine; GO:1901362 organic cyclic compound biosynthetic process; GO:0043436 oxoacid metabolic process; GO:0042436 indole-containing compound catabolic process; GO:0043648 dicarboxylic acid metabolic process; GO:0009165 nucleotide biosynthetic process; GO:0046874 quinolinate metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0046496 nicotinamide nucleotide metabolic process; GO:0050896 response to stimulus; GO:1901566 organonitrogen compound biosynthetic process; GO:0045087 innate immune response; GO:0006576 cellular biogenic amine metabolic process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0009991 response to extracellular stimulus; GO:0019442 tryptophan catabolic process to acetyl-CoA; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0043420 anthranilate metabolic process; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0042430 indole-containing compound metabolic process; GO:0009987 cellular process; GO:0009308 amine metabolic process; GO:0042537 benzene-containing compound metabolic process; GO:0044711 single-organism biosynthetic process; GO:0006950 response to stress; GO:0009074 aromatic amino acid family catabolic process; GO:0044712 single-organism catabolic process; GO:0097053 L-kynurenine catabolic process; GO:0035383 thioester metabolic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0097052 L-kynurenine metabolic process; GO:0044282 small molecule catabolic process; GO:0002376 immune system process; GO:0042402 cellular biogenic amine catabolic process; GO:0010033 response to organic substance; GO:0034341 response to interferon-gamma; GO:0044238 primary metabolic process; GO:1901605 alpha-amino acid metabolic process; GO:0007584 response to nutrient; GO:1901576 organic substance biosynthetic process; GO:0006637 acyl-CoA metabolic process; GO:0019805 quinolinate biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0009435 NAD biosynthetic process; GO:0046218 indolalkylamine catabolic process; GO:1901565 organonitrogen compound catabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0070189 kynurenine metabolic process; GO:0044283 small molecule biosynthetic process; GO:0019752 carboxylic acid metabolic process; GO:0016054 organic acid catabolic process; GO:0019637 organophosphate metabolic process; GO:0006568 tryptophan metabolic process; GO:0031667 response to nutrient levels; GO:0006955 immune response; GO:0009056 catabolic process; GO:0046700 heterocycle catabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0005829 cytosol; GO:0005739 mitochondrion; GO:0044444 cytoplasmic part; ","GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds; GO:0046983 protein dimerization activity; GO:0043167 ion binding; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0048037 cofactor binding; GO:0030170 pyridoxal phosphate binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0030429 kynureninase activity; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0042803 protein homodimerization activity; GO:0043168 anion binding; GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances; ","K01556","KYNU; kynureninase [EC:3.7.1.3]","hsa00380 Tryptophan metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR015424; IPR000192; IPR015422; IPR015421; ","\"Pyridoxal phosphate-dependent transferase; Aminotransferase class V domain; Pyridoxal phosphate-dependent transferase, major region, subdomain 2; Pyridoxal phosphate-dependent transferase, major region, subdomain 1; \"\r"]
["Q16795","NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFA9","NDUFA9",42.509,32.728,18.6,7,14,7,0.997,1.012,1.019,0.998,1.012,0.97,0.984,0.316,"mitochondria\r","GO:0051188 cofactor biosynthetic process; GO:0042181 ketone biosynthetic process; GO:0044085 cellular component biogenesis; GO:1901663 quinone biosynthetic process; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0042180 cellular ketone metabolic process; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0006753 nucleoside phosphate metabolic process; GO:0007005 mitochondrion organization; GO:0019693 ribose phosphate metabolic process; GO:0009108 coenzyme biosynthetic process; GO:0006743 ubiquinone metabolic process; GO:0071822 protein complex subunit organization; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0010257 NADH dehydrogenase complex assembly; GO:0055114 oxidation-reduction process; GO:1901661 quinone metabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006119 oxidative phosphorylation; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0006732 coenzyme metabolic process; GO:0006120 mitochondrial electron transport, NADH to ubiquinone; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0006814 sodium ion transport; GO:0051186 cofactor metabolic process; GO:0006810 transport; GO:0097031 mitochondrial respiratory chain complex I biogenesis; GO:0009161 ribonucleoside monophosphate metabolic process; GO:1901006 ubiquinone-6 biosynthetic process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0022900 electron transport chain; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0070271 protein complex biogenesis; GO:0033108 mitochondrial respiratory chain complex assembly; GO:0016310 phosphorylation; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0042773 ATP synthesis coupled electron transport; GO:0009259 ribonucleotide metabolic process; GO:0030001 metal ion transport; GO:0022904 respiratory electron transport chain; GO:1901004 ubiquinone-6 metabolic process; GO:0071704 organic substance metabolic process; GO:0032981 mitochondrial respiratory chain complex I assembly; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0006812 cation transport; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009119 ribonucleoside metabolic process; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0043623 cellular protein complex assembly; GO:0046034 ATP metabolic process; GO:0034622 cellular macromolecular complex assembly; GO:0006744 ubiquinone biosynthetic process; GO:0044711 single-organism biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0045333 cellular respiration; GO:0044249 cellular biosynthetic process; GO:0006163 purine nucleotide metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0046128 purine ribonucleoside metabolic process; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0006811 ion transport; GO:0044283 small molecule biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0051179 localization; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:0015672 monovalent inorganic cation transport; GO:0071840 cellular component organization or biogenesis; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0045271 respiratory chain complex I; GO:0032991 macromolecular complex; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0005747 mitochondrial respiratory chain complex I; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0098803 respiratory chain complex; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005759 mitochondrial matrix; GO:0044429 mitochondrial part; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0031981 nuclear lumen; GO:0005739 mitochondrion; GO:0005746 mitochondrial respiratory chain; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0030964 NADH dehydrogenase complex; GO:0031975 envelope; GO:1990204 oxidoreductase complex; GO:0043234 protein complex; GO:0031966 mitochondrial membrane; GO:0070469 respiratory chain; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:0003954 NADH dehydrogenase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0050136 NADH dehydrogenase (quinone) activity; GO:0005515 protein binding; GO:0048037 cofactor binding; GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; GO:0008137 NADH dehydrogenase (ubiquinone) activity; GO:0050662 coenzyme binding; GO:0032403 protein complex binding; GO:0016491 oxidoreductase activity; ","K03953","NDUFA9; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9","hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); ","IPR001509; IPR016040; ","NAD-dependent epimerase/dehydratase; NAD(P)-binding domain; \r"]
["Q16822","Phosphoenolpyruvate carboxykinase [GTP], mitochondrial OS=Homo sapiens OX=9606 GN=PCK2","PCK2",70.698,56.069,20.9,12,21,12,0.99,1.042,1.018,0.99,0.96,1.041,0.981,0.515,"mitochondria\r","GO:0065008 regulation of biological quality; GO:0019362 pyridine nucleotide metabolic process; GO:0042593 glucose homeostasis; GO:0050796 regulation of insulin secretion; GO:0002793 positive regulation of peptide secretion; GO:0009749 response to glucose; GO:0044237 cellular metabolic process; GO:0071345 cellular response to cytokine stimulus; GO:0009607 response to biotic stimulus; GO:0006006 glucose metabolic process; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0006094 gluconeogenesis; GO:0032879 regulation of localization; GO:0071333 cellular response to glucose stimulus; GO:0048545 response to steroid hormone; GO:0001678 cellular glucose homeostasis; GO:0071322 cellular response to carbohydrate stimulus; GO:0032787 monocarboxylic acid metabolic process; GO:0009719 response to endogenous stimulus; GO:0009743 response to carbohydrate; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0006116 NADH oxidation; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006107 oxaloacetate metabolic process; GO:0006732 coenzyme metabolic process; GO:0005975 carbohydrate metabolic process; GO:0051704 multi-organism process; GO:0046883 regulation of hormone secretion; GO:0019674 NAD metabolic process; GO:0044710 single-organism metabolic process; GO:0034284 response to monosaccharide; GO:0050714 positive regulation of protein secretion; GO:0010817 regulation of hormone levels; GO:0051223 regulation of protein transport; GO:0043436 oxoacid metabolic process; GO:0051047 positive regulation of secretion; GO:0050794 regulation of cellular process; GO:0046496 nicotinamide nucleotide metabolic process; GO:1901700 response to oxygen-containing compound; GO:0046364 monosaccharide biosynthetic process; GO:0090277 positive regulation of peptide hormone secretion; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0033500 carbohydrate homeostasis; GO:0032880 regulation of protein localization; GO:0048878 chemical homeostasis; GO:0009617 response to bacterium; GO:0090087 regulation of peptide transport; GO:0044711 single-organism biosynthetic process; GO:0032496 response to lipopolysaccharide; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0071326 cellular response to monosaccharide stimulus; GO:1904951 positive regulation of establishment of protein localization; GO:0006793 phosphorus metabolic process; GO:0044283 small molecule biosynthetic process; GO:0046887 positive regulation of hormone secretion; GO:0019637 organophosphate metabolic process; GO:0019318 hexose metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0071331 cellular response to hexose stimulus; GO:0009746 response to hexose; GO:0019319 hexose biosynthetic process; GO:0023051 regulation of signaling; GO:0009117 nucleotide metabolic process; GO:0051046 regulation of secretion; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0072524 pyridine-containing compound metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0010646 regulation of cell communication; GO:0006753 nucleoside phosphate metabolic process; GO:0034612 response to tumor necrosis factor; GO:0070887 cellular response to chemical stimulus; GO:0034097 response to cytokine; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0002237 response to molecule of bacterial origin; GO:0055114 oxidation-reduction process; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0019725 cellular homeostasis; GO:1903530 regulation of secretion by cell; GO:0051384 response to glucocorticoid; GO:0051050 positive regulation of transport; GO:0051186 cofactor metabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:1903532 positive regulation of secretion by cell; GO:0006082 organic acid metabolic process; GO:0051222 positive regulation of protein transport; GO:0043648 dicarboxylic acid metabolic process; GO:0016051 carbohydrate biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0071356 cellular response to tumor necrosis factor; GO:0071310 cellular response to organic substance; GO:0006734 NADH metabolic process; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0070201 regulation of establishment of protein localization; GO:0055082 cellular chemical homeostasis; GO:0071704 organic substance metabolic process; GO:0033993 response to lipid; GO:0042592 homeostatic process; GO:0002791 regulation of peptide secretion; GO:0006090 pyruvate metabolic process; GO:0023056 positive regulation of signaling; GO:0031960 response to corticosteroid; GO:0005996 monosaccharide metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0010647 positive regulation of cell communication; GO:0050708 regulation of protein secretion; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0032024 positive regulation of insulin secretion; GO:0051049 regulation of transport; GO:0006807 nitrogen compound metabolic process; GO:0048518 positive regulation of biological process; GO:0071548 response to dexamethasone; GO:1901701 cellular response to oxygen-containing compound; GO:0090276 regulation of peptide hormone secretion; GO:0019752 carboxylic acid metabolic process; GO:0009725 response to hormone; GO:0065007 biological regulation; GO:1901654 response to ketone; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0044429 mitochondrial part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:1901265 nucleoside phosphate binding; GO:0004611 phosphoenolpyruvate carboxykinase activity; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016829 lyase activity; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0016830 carbon-carbon lyase activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0016831 carboxy-lyase activity; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0004613 phosphoenolpyruvate carboxykinase (GTP) activity; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0036094 small molecule binding; ","K01596","E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]","hsa04920 Adipocytokine signaling pathway - Homo sapiens (human); hsa03320 PPAR signaling pathway - Homo sapiens (human); hsa00620 Pyruvate metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa04964 Proximal tubule bicarbonate reclamation - Homo sapiens (human); hsa00020 Citrate cycle (TCA cycle) - Homo sapiens (human); hsa04922 Glucagon signaling pathway - Homo sapiens (human); hsa04910 Insulin signaling pathway - Homo sapiens (human); hsa04152 AMPK signaling pathway - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa04068 FoxO signaling pathway - Homo sapiens (human); hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human); hsa04931 Insulin resistance - Homo sapiens (human); ","IPR008210; IPR013035; ","\"Phosphoenolpyruvate carboxykinase, N-terminal; Phosphoenolpyruvate carboxykinase, C-terminal; \"\r"]
["Q16853","Membrane primary amine oxidase OS=Homo sapiens OX=9606 GN=AOC3","AOC3",84.621,107.18,25.4,16,31,16,1.182,1.163,1.143,0.855,0.901,0.835,0.743,2.61E-4,"endoplasmic reticulum\r","GO:0071466 cellular response to xenobiotic stimulus; GO:0051716 cellular response to stimulus; GO:0006950 response to stress; GO:0055114 oxidation-reduction process; GO:0046677 response to antibiotic; GO:0006807 nitrogen compound metabolic process; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0022610 biological adhesion; GO:0008152 metabolic process; GO:0042221 response to chemical; GO:0009410 response to xenobiotic stimulus; GO:0006805 xenobiotic metabolic process; GO:0044710 single-organism metabolic process; GO:0006954 inflammatory response; GO:0007155 cell adhesion; GO:0006952 defense response; GO:0009987 cellular process; GO:0009308 amine metabolic process; GO:0070887 cellular response to chemical stimulus; GO:1901564 organonitrogen compound metabolic process; ","GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042995 cell projection; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0098858 actin-based cell projection; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0005769 early endosome; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0005902 microvillus; GO:0005768 endosome; GO:0009986 cell surface; GO:0005794 Golgi apparatus; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0046982 protein heterodimerization activity; GO:0052595 aliphatic-amine oxidase activity; GO:0043167 ion binding; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:0005507 copper ion binding; GO:0048037 cofactor binding; GO:0052596 phenethylamine:oxygen oxidoreductase (deaminating) activity; GO:0016491 oxidoreductase activity; GO:0042802 identical protein binding; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity; GO:0052594 aminoacetone:oxygen oxidoreductase(deaminating) activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0008131 primary amine oxidase activity; GO:0005509 calcium ion binding; GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors; GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor; GO:0048038 quinone binding; ","K00276","AOC3; primary-amine oxidase [EC:1.4.3.21]","hsa00360 Phenylalanine metabolism - Homo sapiens (human); hsa00410 beta-Alanine metabolism - Homo sapiens (human); hsa00350 Tyrosine metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00260 Glycine, serine and threonine metabolism - Homo sapiens (human); ","IPR016182; IPR015800; IPR015802; IPR015798; ","\"Copper amine oxidase, N-terminal; Copper amine oxidase, N2-terminal; Copper amine oxidase, N3-terminal; Copper amine oxidase, C-terminal; \"\r"]
["Q16881","Thioredoxin reductase 1, cytoplasmic OS=Homo sapiens OX=9606 GN=TXNRD1","TXNRD1",70.905,5.711,4.2,3,3,3,1.017,0.975,0.982,0.983,1.118,0.932,1.02,0.777,"cytoplasm\r","GO:0044700 single organism signaling; GO:0050794 regulation of cellular process; GO:0065008 regulation of biological quality; GO:0006725 cellular aromatic compound metabolic process; GO:0015949 nucleobase-containing small molecule interconversion; GO:0045454 cell redox homeostasis; GO:1901700 response to oxygen-containing compound; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:1990748 cellular detoxification; GO:0007154 cell communication; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0006979 response to oxidative stress; GO:0034641 cellular nitrogen compound metabolic process; GO:0098869 cellular oxidant detoxification; GO:0010035 response to inorganic substance; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0051716 cellular response to stimulus; GO:0006950 response to stress; GO:0055114 oxidation-reduction process; GO:0009636 response to toxic substance; GO:0044281 small molecule metabolic process; GO:0000302 response to reactive oxygen species; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0019725 cellular homeostasis; GO:0023052 signaling; GO:0044238 primary metabolic process; GO:0001887 selenium compound metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0044710 single-organism metabolic process; GO:0000305 response to oxygen radical; GO:0098754 detoxification; GO:0065007 biological regulation; ","GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044452 nucleolar part; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0001650 fibrillar center; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0015035 protein disulfide oxidoreductase activity; GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:1901265 nucleoside phosphate binding; GO:0050660 flavin adenine dinucleotide binding; GO:0098626 methylseleninic acid reductase activity; GO:0004791 thioredoxin-disulfide reductase activity; GO:0043167 ion binding; GO:0016209 antioxidant activity; GO:0005515 protein binding; GO:0098625 methylselenol reductase activity; GO:0000166 nucleotide binding; GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor; GO:0048037 cofactor binding; GO:0016491 oxidoreductase activity; GO:0009055 electron carrier activity; GO:0015036 disulfide oxidoreductase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016667 oxidoreductase activity, acting on a sulfur group of donors; GO:0043168 anion binding; GO:0036094 small molecule binding; GO:0050662 coenzyme binding; ","K00384",null,null,"IPR016156; IPR002109; IPR004099; IPR012336; IPR023753; ","\"FAD/NAD-linked reductase, dimerisation domain; Glutaredoxin; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Thioredoxin-like fold; FAD/NAD(P)-binding domain; \"\r"]
["Q1KMD3","Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2","HNRNPUL2",85.104,108.23,27.6,17,27,17,0.958,0.878,0.995,1.032,1.042,1.058,1.106,0.0534,"nucleus\r",null,"GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005515 protein binding; GO:0005488 binding; GO:0003676 nucleic acid binding; ",{"$nulls":3},"IPR003034; IPR027417; IPR001870; IPR013320; IPR003877; ","SAP domain; P-loop containing nucleoside triphosphate hydrolase; B30.2/SPRY domain; Concanavalin A-like lectin/glucanase domain; SPRY domain; \r"]
["Q29RF7","Sister chromatid cohesion protein PDS5 homolog A OS=Homo sapiens OX=9606 GN=PDS5A","PDS5A",150.83,13.353,5,6,9,3,0.957,0.993,0.947,1.035,1.077,1.013,1.079,0.0302,"cytoplasm\r","GO:0007067 mitotic nuclear division; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0000819 sister chromatid segregation; GO:0043170 macromolecule metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0051716 cellular response to stimulus; GO:0000278 mitotic cell cycle; GO:0007059 chromosome segregation; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0008156 negative regulation of DNA replication; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0051052 regulation of DNA metabolic process; GO:0051053 negative regulation of DNA metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0051301 cell division; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0033554 cellular response to stress; GO:0006275 regulation of DNA replication; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0006259 DNA metabolic process; GO:0048285 organelle fission; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:1903047 mitotic cell cycle process; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009987 cellular process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0006950 response to stress; GO:0000070 mitotic sister chromatid segregation; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0007064 mitotic sister chromatid cohesion; GO:0006974 cellular response to DNA damage stimulus; GO:0009890 negative regulation of biosynthetic process; GO:0006281 DNA repair; GO:0051276 chromosome organization; GO:0098813 nuclear chromosome segregation; GO:0006996 organelle organization; GO:0000280 nuclear division; GO:0007062 sister chromatid cohesion; GO:0022402 cell cycle process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0043232 intracellular non-membrane-bounded organelle; GO:0071944 cell periphery; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0005886 plasma membrane; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0098687 chromosomal region; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0000785 chromatin; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0000775 chromosome, centromeric region; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0005488 binding; ","K11267",null,null,"IPR011989; IPR016024; ","Armadillo-like helical; Armadillo-type fold; \r"]
["Q2M389","WASH complex subunit 4 OS=Homo sapiens OX=9606 GN=WASHC4","WASHC4",136.4,13.704,3,4,4,4,0.867,1.081,1.052,1.101,0.994,0.917,1.004,0.949,"cytoplasm\r","GO:0016043 cellular component organization; GO:0010256 endomembrane system organization; GO:0016050 vesicle organization; GO:0071702 organic substance transport; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006810 transport; GO:0016197 endosomal transport; GO:0045184 establishment of protein localization; GO:0006996 organelle organization; GO:0051179 localization; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0007032 endosome organization; GO:0009987 cellular process; GO:0071840 cellular component organization or biogenesis; ","GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0031410 cytoplasmic vesicle; GO:0071203 WASH complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0012505 endomembrane system; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0005769 early endosome; GO:0043226 organelle; GO:0005622 intracellular; GO:0044464 cell part; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ",null,"K18465","MRT43; WASH complex subunit 7","hsa04144 Endocytosis - Homo sapiens (human); ","IPR028283; IPR028282; IPR028191; ","\"WASH complex subunit 7, C-terminal; WASH complex subunit 7, central domain; WASH complex subunit 7, N-terminal; \"\r"]
["Q2TAL8","Glutamine-rich protein 1 OS=Homo sapiens OX=9606 GN=QRICH1","QRICH1",86.435,7.916,3.7,3,3,3,0.959,0.949,0.901,1.033,1.025,1.131,1.135,0.027,"nucleus\r","GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044699 single-organism process; GO:2001141 regulation of RNA biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0006355 regulation of transcription, DNA-templated; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0032501 multicellular organismal process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0044767 single-organism developmental process; GO:0006996 organelle organization; GO:0022603 regulation of anatomical structure morphogenesis; GO:0019222 regulation of metabolic process; GO:0051128 regulation of cellular component organization; GO:0050793 regulation of developmental process; GO:0022604 regulation of cell morphogenesis; GO:0048856 anatomical structure development; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding; GO:0003677 DNA binding; GO:0005488 binding; GO:0001071 nucleic acid binding transcription factor activity; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0003700 transcription factor activity, sequence-specific DNA binding; ",{"$nulls":3},"IPR021893; IPR011029; ","Protein of unknown function DUF3504; Death-like domain; \r"]
["Q32MZ4","Leucine-rich repeat flightless-interacting protein 1 OS=Homo sapiens OX=9606 GN=LRRFIP1","LRRFIP1",89.252,44.119,12.1,8,8,8,0.853,0.856,0.941,1.078,1.138,1.123,1.26,0.003,"nucleus\r","GO:0032481 positive regulation of type I interferon production; GO:0097659 nucleic acid-templated transcription; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0051253 negative regulation of RNA metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0044093 positive regulation of molecular function; GO:0043170 macromolecule metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0051092 positive regulation of NF-kappaB transcription factor activity; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0051090 regulation of sequence-specific DNA binding transcription factor activity; GO:1902679 negative regulation of RNA biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0032479 regulation of type I interferon production; GO:0006725 cellular aromatic compound metabolic process; GO:0001819 positive regulation of cytokine production; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0051239 regulation of multicellular organismal process; GO:0071704 organic substance metabolic process; GO:0045892 negative regulation of transcription, DNA-templated; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0044238 primary metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0009890 negative regulation of biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0001817 regulation of cytokine production; GO:0010467 gene expression; GO:0031327 negative regulation of cellular biosynthetic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0043232 intracellular non-membrane-bounded organelle; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005886 plasma membrane; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0005856 cytoskeleton; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0050839 cell adhesion molecule binding; GO:0003723 RNA binding; GO:0003677 DNA binding; GO:0042802 identical protein binding; GO:0042803 protein homodimerization activity; GO:0003725 double-stranded RNA binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0046983 protein dimerization activity; GO:0003676 nucleic acid binding; GO:0005515 protein binding; "]
["Q32P44","Echinoderm microtubule-associated protein-like 3 OS=Homo sapiens OX=9606 GN=EML3","EML3",95.196,9.0805,2.7,2,2,2,0.944,0.854,0.972,0.942,1.054,1.223,1.162,0.162,"cytoplasm\r",null,"GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0005874 microtubule; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0099081 supramolecular polymer; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0005856 cytoskeleton; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; ","GO:0015631 tubulin binding; GO:0005515 protein binding; GO:0008092 cytoskeletal protein binding; GO:0008017 microtubule binding; GO:0005488 binding; ","K18596",null,null,"IPR005108; IPR017986; IPR015943; IPR011047; ","HELP; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain; Quinoprotein alcohol dehydrogenase-like superfamily; \r"]
["Q3SY69","Mitochondrial 10-formyltetrahydrofolate dehydrogenase OS=Homo sapiens OX=9606 GN=ALDH1L2","ALDH1L2",101.74,32.154,10.3,9,12,6,1.144,1.26,1.372,0.757,0.69,0.813,0.599,1.92E-3,"mitochondria\r","GO:0043648 dicarboxylic acid metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0009258 10-formyltetrahydrofolate catabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0046655 folic acid metabolic process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0006766 vitamin metabolic process; GO:0008152 metabolic process; GO:0043649 dicarboxylic acid catabolic process; GO:0006730 one-carbon metabolic process; GO:0051187 cofactor catabolic process; GO:0046483 heterocycle metabolic process; GO:0006575 cellular modified amino acid metabolic process; GO:1901361 organic cyclic compound catabolic process; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009987 cellular process; GO:0006767 water-soluble vitamin metabolic process; GO:0042560 pteridine-containing compound catabolic process; GO:0046653 tetrahydrofolate metabolic process; GO:0055114 oxidation-reduction process; GO:0044712 single-organism catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0044282 small molecule catabolic process; GO:0006732 coenzyme metabolic process; GO:0043603 cellular amide metabolic process; GO:0042558 pteridine-containing compound metabolic process; GO:0051186 cofactor metabolic process; GO:0046395 carboxylic acid catabolic process; GO:0019439 aromatic compound catabolic process; GO:1901575 organic substance catabolic process; GO:1901565 organonitrogen compound catabolic process; GO:0042219 cellular modified amino acid catabolic process; GO:0044710 single-organism metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0016054 organic acid catabolic process; GO:0009109 coenzyme catabolic process; GO:0009256 10-formyltetrahydrofolate metabolic process; GO:0006082 organic acid metabolic process; GO:0006760 folic acid-containing compound metabolic process; GO:0009056 catabolic process; GO:0009397 folic acid-containing compound catabolic process; GO:0043436 oxoacid metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0046700 heterocycle catabolic process; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0044429 mitochondrial part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors; GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor; GO:0003824 catalytic activity; GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors; GO:0016741 transferase activity, transferring one-carbon groups; GO:0016742 hydroxymethyl-, formyl- and related transferase activity; GO:0016155 formyltetrahydrofolate dehydrogenase activity; GO:0016740 transferase activity; GO:0016491 oxidoreductase activity; GO:0004029 aldehyde dehydrogenase (NAD) activity; ","K00289","ALDH1L; formyltetrahydrofolate dehydrogenase [EC:1.5.1.6]","hsa00670 One carbon pool by folate - Homo sapiens (human); ","IPR005793; IPR016161; IPR015590; IPR016162; IPR009081; IPR016163; IPR011034; IPR002376; ","\"Formyl transferase, C-terminal; Aldehyde/histidinol dehydrogenase; Aldehyde dehydrogenase domain; Aldehyde dehydrogenase N-terminal domain; Phosphopantetheine binding ACP domain; Aldehyde dehydrogenase, C-terminal; Formyl transferase, C-terminal-like; Formyl transferase, N-terminal; \"\r"]
["Q3ZCM7","Tubulin beta-8 chain OS=Homo sapiens OX=9606 GN=TUBB8","TUBB8",49.775,79.24,24.3,9,58,2,0.966,0.917,1.057,1.084,1.031,0.95,1.043,0.5,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0000003 reproduction; GO:0048599 oocyte development; GO:0016043 cellular component organization; GO:0090306 spindle assembly involved in meiosis; GO:0021700 developmental maturation; GO:1903046 meiotic cell cycle process; GO:0022414 reproductive process; GO:0007292 female gamete generation; GO:0048285 organelle fission; GO:0048869 cellular developmental process; GO:0007051 spindle organization; GO:0044699 single-organism process; GO:0048468 cell development; GO:0030154 cell differentiation; GO:0051225 spindle assembly; GO:0070925 organelle assembly; GO:0022607 cellular component assembly; GO:0001556 oocyte maturation; GO:0044702 single organism reproductive process; GO:0048469 cell maturation; GO:0007281 germ cell development; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0032502 developmental process; GO:0003006 developmental process involved in reproduction; GO:0048477 oogenesis; GO:0009994 oocyte differentiation; GO:0000212 meiotic spindle organization; GO:0019953 sexual reproduction; GO:0044763 single-organism cellular process; GO:0051321 meiotic cell cycle; GO:0007017 microtubule-based process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0007276 gamete generation; GO:0032504 multicellular organism reproduction; GO:0000226 microtubule cytoskeleton organization; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0044703 multi-organism reproductive process; GO:0022412 cellular process involved in reproduction in multicellular organism; GO:0000280 nuclear division; GO:0007126 meiotic nuclear division; GO:0022402 cell cycle process; GO:0007056 spindle assembly involved in female meiosis; GO:0007143 female meiotic division; GO:0048609 multicellular organismal reproductive process; GO:0048856 anatomical structure development; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0099513 polymeric cytoskeletal fiber; GO:0005874 microtubule; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0005623 cell; GO:0099080 supramolecular complex; GO:0005576 extracellular region; GO:0005819 spindle; GO:0044422 organelle part; GO:0099081 supramolecular polymer; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0005856 cytoskeleton; GO:0072687 meiotic spindle; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0005200 structural constituent of cytoskeleton; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0003924 GTPase activity; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019001 guanyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005525 GTP binding; GO:0005198 structural molecule activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0036094 small molecule binding; ","K07375","TUBB; tubulin beta","hsa04540 Gap junction - Homo sapiens (human); hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); ","IPR003008; IPR023123; IPR008280; IPR018316; ","\"Tubulin/FtsZ, GTPase domain; Tubulin, C-terminal; Tubulin/FtsZ, C-terminal; Tubulin/FtsZ, 2-layer sandwich domain; \"\r"]
["Q49A26","Putative oxidoreductase GLYR1 OS=Homo sapiens OX=9606 GN=GLYR1","GLYR1",60.556,8.6593,2.4,1,1,1,0.945,1.047,0.974,1.035,1.049,0.96,1.026,0.559,"nucleus\r","GO:0044699 single-organism process; GO:0008152 metabolic process; GO:0055114 oxidation-reduction process; GO:0044710 single-organism metabolic process; ","GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0044464 cell part; GO:0005622 intracellular; GO:0005694 chromosome; GO:0043227 membrane-bounded organelle; GO:0044815 DNA packaging complex; GO:0032993 protein-DNA complex; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0000786 nucleosome; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0000785 chromatin; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0042393 histone binding; GO:0003677 DNA binding; GO:1901265 nucleoside phosphate binding; GO:0035064 methylated histone binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0048037 cofactor binding; GO:0016491 oxidoreductase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016614 oxidoreductase activity, acting on CH-OH group of donors; GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity; GO:0003824 catalytic activity; GO:0051287 NAD binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0036094 small molecule binding; GO:0050662 coenzyme binding; ",{"$nulls":3},"IPR006115; IPR008927; IPR013328; IPR016040; IPR029154; IPR000313; ","\"6-phosphogluconate dehydrogenase, NADP-binding; 6-phosphogluconate dehydrogenase C-terminal domain-like; 6-phosphogluconate dehydrogenase, domain 2; NAD(P)-binding domain; 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain; PWWP domain; \"\r"]
["Q4G0N4","NAD kinase 2, mitochondrial OS=Homo sapiens OX=9606 GN=NADK2","NADK2",49.432,25.398,8.4,3,5,3,1.078,1.188,0.93,0.966,0.899,0.882,0.86,0.126,"mitochondria\r","GO:0051188 cofactor biosynthetic process; GO:0006739 NADP metabolic process; GO:0016310 phosphorylation; GO:0019362 pyridine nucleotide metabolic process; GO:0009165 nucleotide biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0006741 NADP biosynthetic process; GO:0046496 nicotinamide nucleotide metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0019363 pyridine nucleotide biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0072524 pyridine-containing compound metabolic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0072525 pyridine-containing compound biosynthetic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006753 nucleoside phosphate metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009108 coenzyme biosynthetic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0018130 heterocycle biosynthetic process; GO:0044711 single-organism biosynthetic process; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0006732 coenzyme metabolic process; GO:0019359 nicotinamide nucleotide biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0051186 cofactor metabolic process; GO:0090407 organophosphate biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0019674 NAD metabolic process; GO:0044710 single-organism metabolic process; GO:0019637 organophosphate metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044444 cytoplasmic part; ","GO:0003951 NAD+ kinase activity; GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0046983 protein dimerization activity; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0042802 identical protein binding; GO:0016301 kinase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K00858","ppnK; NAD+ kinase [EC:2.7.1.23]","hsa00760 Nicotinate and nicotinamide metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR017438; IPR016064; IPR017437; ","\"Inorganic polyphosphate/ATP-NAD kinase, domain 1; NAD kinase/diacylglycerol kinase-like domain; ATP-NAD kinase, PpnK-type, all-beta; \"\r"]
["Q4G176","Acyl-CoA synthetase family member 3, mitochondrial OS=Homo sapiens OX=9606 GN=ACSF3","ACSF3",64.129,5.4649,4.3,3,3,3,0.848,1.122,0.848,1.141,1.024,1.025,1.132,0.258,"mitochondria\r","GO:0051188 cofactor biosynthetic process; GO:0043648 dicarboxylic acid metabolic process; GO:0046949 fatty-acyl-CoA biosynthetic process; GO:0016053 organic acid biosynthetic process; GO:0035337 fatty-acyl-CoA metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0035384 thioester biosynthetic process; GO:0044272 sulfur compound biosynthetic process; GO:0008610 lipid biosynthetic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0043649 dicarboxylic acid catabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0044248 cellular catabolic process; GO:0009108 coenzyme biosynthetic process; GO:0009987 cellular process; GO:0006629 lipid metabolic process; GO:0006790 sulfur compound metabolic process; GO:0044711 single-organism biosynthetic process; GO:0044712 single-organism catabolic process; GO:0071616 acyl-CoA biosynthetic process; GO:0044281 small molecule metabolic process; GO:0035383 thioester metabolic process; GO:0044763 single-organism cellular process; GO:0006732 coenzyme metabolic process; GO:0035336 long-chain fatty-acyl-CoA metabolic process; GO:0044282 small molecule catabolic process; GO:0006631 fatty acid metabolic process; GO:0044238 primary metabolic process; GO:0006633 fatty acid biosynthetic process; GO:0035338 long-chain fatty-acyl-CoA biosynthetic process; GO:1901576 organic substance biosynthetic process; GO:0006637 acyl-CoA metabolic process; GO:0044249 cellular biosynthetic process; GO:0051186 cofactor metabolic process; GO:0046395 carboxylic acid catabolic process; GO:1901575 organic substance catabolic process; GO:0046394 carboxylic acid biosynthetic process; GO:0090410 malonate catabolic process; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0044283 small molecule biosynthetic process; GO:0019752 carboxylic acid metabolic process; GO:0016054 organic acid catabolic process; GO:0006082 organic acid metabolic process; GO:0072330 monocarboxylic acid biosynthetic process; GO:0009056 catabolic process; GO:0043436 oxoacid metabolic process; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0016874 ligase activity; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016877 ligase activity, forming carbon-sulfur bonds; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0015645 fatty acid ligase activity; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0090409 malonyl-CoA synthetase activity; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0031957 very long-chain fatty acid-CoA ligase activity; GO:0016878 acid-thiol ligase activity; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K18660","ACSF3; malonyl-CoA/methylmalonyl-CoA synthetase [EC:6.2.1.-]","hsa00280 Valine, leucine and isoleucine degradation - Homo sapiens (human); ","IPR025110; IPR000873; ","AMP-binding enzyme C-terminal domain; AMP-dependent synthetase/ligase; \r"]
["Q4VC31","Coiled-coil domain-containing protein 58 OS=Homo sapiens OX=9606 GN=CCDC58","CCDC58",16.62,11.076,13.9,2,3,2,0.921,0.967,1.043,0.977,0.985,1.107,1.047,0.447,"extracellular\r",null,"GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044444 cytoplasmic part; "]
["Q504Q3","PAN2-PAN3 deadenylation complex catalytic subunit PAN2 OS=Homo sapiens OX=9606 GN=PAN2","PAN2",135.37,6.5153,1.3,1,1,1,0.953,1.103,1.099,1.101,0.846,0.918,0.908,0.335,"nucleus\r","GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0048519 negative regulation of biological process; GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0044248 cellular catabolic process; GO:1901361 organic cyclic compound catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0043170 macromolecule metabolic process; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0006396 RNA processing; GO:0010468 regulation of gene expression; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening; GO:0044238 primary metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0009892 negative regulation of metabolic process; GO:0006397 mRNA processing; GO:0006401 RNA catabolic process; GO:0016070 RNA metabolic process; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0090501 RNA phosphodiester bond hydrolysis; GO:0050789 regulation of biological process; GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; GO:0090304 nucleic acid metabolic process; GO:0009057 macromolecule catabolic process; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0010467 gene expression; GO:0090305 nucleic acid phosphodiester bond hydrolysis; GO:0009056 catabolic process; GO:0016071 mRNA metabolic process; GO:0065007 biological regulation; GO:0046700 heterocycle catabolic process; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0031251 PAN complex; GO:0000932 P-body; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0043228 non-membrane-bounded organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:0035770 ribonucleoprotein granule; GO:1990904 ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0030529 intracellular ribonucleoprotein complex; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0000175 3'-5'-exoribonuclease activity; GO:0016896 exoribonuclease activity, producing 5'-phosphomonoesters; GO:0008408 3'-5' exonuclease activity; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters; GO:0097159 organic cyclic compound binding; GO:0004535 poly(A)-specific ribonuclease activity; GO:1901363 heterocyclic compound binding; GO:0003824 catalytic activity; GO:0004532 exoribonuclease activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0004518 nuclease activity; GO:0016788 hydrolase activity, acting on ester bonds; GO:0004527 exonuclease activity; GO:0004540 ribonuclease activity; ","K12571","PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]","hsa03018 RNA degradation - Homo sapiens (human); ","IPR017986; IPR015943; IPR028889; IPR012337; IPR013520; IPR028881; ","\"WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain; Ubiquitin specific protease domain; Ribonuclease H-like domain; Exonuclease, RNase T/DNA polymerase III; PAN2 domain; \"\r"]
["Q53FA7","Quinone oxidoreductase PIG3 OS=Homo sapiens OX=9606 GN=TP53I3","TP53I3",35.536,8.0016,9.6,5,5,5,1.036,0.931,1.102,0.996,0.875,0.947,0.918,0.246,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0006739 NADP metabolic process; GO:0010941 regulation of cell death; GO:0019362 pyridine nucleotide metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0046496 nicotinamide nucleotide metabolic process; GO:0009117 nucleotide metabolic process; GO:0043067 regulation of programmed cell death; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0072524 pyridine-containing compound metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0006732 coenzyme metabolic process; GO:0044238 primary metabolic process; GO:0051186 cofactor metabolic process; GO:0050789 regulation of biological process; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0019637 organophosphate metabolic process; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; GO:1901564 organonitrogen compound metabolic process; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:1901265 nucleoside phosphate binding; GO:0070402 NADPH binding; GO:0043167 ion binding; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0048037 cofactor binding; GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; GO:0016491 oxidoreductase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0042803 protein homodimerization activity; GO:0050661 NADP binding; GO:0043168 anion binding; GO:0048038 quinone binding; GO:0003960 NADPH:quinone reductase activity; GO:0050662 coenzyme binding; GO:0036094 small molecule binding; ","K10133","TP53I3; tumor protein p53-inducible protein 3 [EC:1.-.-.-]","hsa04115 p53 signaling pathway - Homo sapiens (human); ","IPR011032; IPR020843; IPR016040; IPR013154; IPR013149; ","\"GroES-like; Polyketide synthase, enoylreductase domain; NAD(P)-binding domain; Alcohol dehydrogenase, N-terminal; Alcohol dehydrogenase, C-terminal; \"\r"]
["Q53H12","Acylglycerol kinase, mitochondrial OS=Homo sapiens OX=9606 GN=AGK","AGK",47.137,8.7588,6.9,3,3,3,1.052,1.209,0.931,1.067,0.855,0.914,0.888,0.307,"cytoplasm\r","GO:0051188 cofactor biosynthetic process; GO:0016310 phosphorylation; GO:0046949 fatty-acyl-CoA biosynthetic process; GO:0046486 glycerolipid metabolic process; GO:0006643 membrane lipid metabolic process; GO:0006672 ceramide metabolic process; GO:0035337 fatty-acyl-CoA metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044255 cellular lipid metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:0035384 thioester biosynthetic process; GO:0044272 sulfur compound biosynthetic process; GO:0006796 phosphate-containing compound metabolic process; GO:0008610 lipid biosynthetic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0030148 sphingolipid biosynthetic process; GO:0030258 lipid modification; GO:0006665 sphingolipid metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009108 coenzyme biosynthetic process; GO:0009987 cellular process; GO:0046467 membrane lipid biosynthetic process; GO:0006629 lipid metabolic process; GO:0006790 sulfur compound metabolic process; GO:0044711 single-organism biosynthetic process; GO:0071616 acyl-CoA biosynthetic process; GO:0044763 single-organism cellular process; GO:0035383 thioester metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0035336 long-chain fatty-acyl-CoA metabolic process; GO:0006732 coenzyme metabolic process; GO:0043603 cellular amide metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0035338 long-chain fatty-acyl-CoA biosynthetic process; GO:0046834 lipid phosphorylation; GO:0044249 cellular biosynthetic process; GO:0006637 acyl-CoA metabolic process; GO:0051186 cofactor metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0043604 amide biosynthetic process; GO:0046513 ceramide biosynthetic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0019867 outer membrane; GO:0044429 mitochondrial part; GO:0098588 bounding membrane of organelle; GO:0031090 organelle membrane; GO:0005741 mitochondrial outer membrane; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005740 mitochondrial envelope; GO:0005622 intracellular; GO:0044464 cell part; GO:0031975 envelope; GO:0098805 whole membrane; GO:0031968 organelle outer membrane; GO:0043227 membrane-bounded organelle; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0003951 NAD+ kinase activity; GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0004143 diacylglycerol kinase activity; GO:0001727 lipid kinase activity; GO:0000166 nucleotide binding; GO:0001729 ceramide kinase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016301 kinase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0047620 acylglycerol kinase activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K09881","AGK; acylglycerol kinase [EC:2.7.1.94]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00561 Glycerolipid metabolism - Homo sapiens (human); ","IPR017438; IPR001206; IPR016064; ","\"Inorganic polyphosphate/ATP-NAD kinase, domain 1; Diacylglycerol kinase, catalytic domain; NAD kinase/diacylglycerol kinase-like domain; \"\r"]
["Q53TN4","Cytochrome b reductase 1 OS=Homo sapiens OX=9606 GN=CYBRD1","CYBRD1",31.641,15.756,15,3,4,3,1.145,1.202,1.097,0.802,0.852,0.903,0.742,2.32E-3,"plasma membrane\r","GO:0006879 cellular iron ion homeostasis; GO:0065008 regulation of biological quality; GO:0055076 transition metal ion homeostasis; GO:0050801 ion homeostasis; GO:0055114 oxidation-reduction process; GO:0030003 cellular cation homeostasis; GO:0098771 inorganic ion homeostasis; GO:0044763 single-organism cellular process; GO:0019725 cellular homeostasis; GO:0055072 iron ion homeostasis; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0010038 response to metal ion; GO:0055082 cellular chemical homeostasis; GO:0046916 cellular transition metal ion homeostasis; GO:0042592 homeostatic process; GO:0008152 metabolic process; GO:0042221 response to chemical; GO:0010039 response to iron ion; GO:0055080 cation homeostasis; GO:0006873 cellular ion homeostasis; GO:0044710 single-organism metabolic process; GO:0055065 metal ion homeostasis; GO:0006875 cellular metal ion homeostasis; GO:0010035 response to inorganic substance; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0098862 cluster of actin-based cell projections; GO:0044421 extracellular region part; GO:0005903 brush border; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005765 lysosomal membrane; GO:0070062 extracellular exosome; GO:0098590 plasma membrane region; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0098588 bounding membrane of organelle; GO:0031526 brush border membrane; GO:0044446 intracellular organelle part; GO:0044463 cell projection part; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044459 plasma membrane part; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0031253 cell projection membrane; GO:0005774 vacuolar membrane; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016722 oxidoreductase activity, oxidizing metal ions; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0000293 ferric-chelate reductase activity; GO:0016723 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor; GO:0016491 oxidoreductase activity; ","K08370","CYBRD1; cytochrome b reductase 1 [EC:1.16.5.1]","hsa04978 Mineral absorption - Homo sapiens (human); ","IPR006593; ","Cytochrome b561/ferric reductase transmembrane; \r"]
["Q562E7","WD repeat-containing protein 81 OS=Homo sapiens OX=9606 GN=WDR81","WDR81",211.69,7.6717,1.5,3,3,3,0.991,0.975,1.016,1.056,1.059,0.911,1.015,0.821,"nucleus\r","GO:0050794 regulation of cellular process; GO:0035305 negative regulation of dephosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0010921 regulation of phosphatase activity; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0010923 negative regulation of phosphatase activity; GO:0043086 negative regulation of catalytic activity; GO:0009892 negative regulation of metabolic process; GO:0051346 negative regulation of hydrolase activity; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0010563 negative regulation of phosphorus metabolic process; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0035303 regulation of dephosphorylation; GO:0044092 negative regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0045936 negative regulation of phosphate metabolic process; GO:0065007 biological regulation; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ","K17601",null,null,"IPR000409; IPR017986; IPR015943; IPR011009; ","BEACH domain; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain; Protein kinase-like domain; \r"]
["Q5EBL4","RILP-like protein 1 OS=Homo sapiens OX=9606 GN=RILPL1","RILPL1",47.107,19.982,4.5,1,1,1,0.917,1.069,0.931,1.013,1.086,0.991,1.059,0.35,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0010941 regulation of cell death; GO:0010256 endomembrane system organization; GO:0048869 cellular developmental process; GO:0032989 cellular component morphogenesis; GO:0060271 cilium assembly; GO:0090002 establishment of protein localization to plasma membrane; GO:0044699 single-organism process; GO:0051668 localization within membrane; GO:0044782 cilium organization; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0051649 establishment of localization in cell; GO:0022607 cellular component assembly; GO:0046909 intermembrane transport; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0044765 single-organism transport; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0002064 epithelial cell development; GO:0009888 tissue development; GO:0072657 protein localization to membrane; GO:0044763 single-organism cellular process; GO:0007009 plasma membrane organization; GO:1902582 single-organism intracellular transport; GO:0000902 cell morphogenesis; GO:0006810 transport; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0030030 cell projection organization; GO:0048856 anatomical structure development; GO:0030855 epithelial cell differentiation; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:1903445 protein transport from ciliary membrane to plasma membrane; GO:1990778 protein localization to cell periphery; GO:0048468 cell development; GO:0000904 cell morphogenesis involved in differentiation; GO:0009653 anatomical structure morphogenesis; GO:0030154 cell differentiation; GO:1902578 single-organism localization; GO:0070925 organelle assembly; GO:0006886 intracellular protein transport; GO:1902580 single-organism cellular localization; GO:0034613 cellular protein localization; GO:0090150 establishment of protein localization to membrane; GO:0009987 cellular process; GO:1901214 regulation of neuron death; GO:0044802 single-organism membrane organization; GO:0071702 organic substance transport; GO:0030031 cell projection assembly; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0032594 protein transport within lipid bilayer; GO:0070727 cellular macromolecule localization; GO:0072659 protein localization to plasma membrane; GO:0003382 epithelial cell morphogenesis; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0061024 membrane organization; GO:0051179 localization; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0005654 nucleoplasm; GO:0005815 microtubule organizing center; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0044441 ciliary part; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0005929 cilium; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0036064 ciliary basal body; GO:0031981 nuclear lumen; GO:0044463 cell projection part; GO:0005829 cytosol; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005813 centrosome; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0051959 dynein light intermediate chain binding; GO:0031267 small GTPase binding; GO:0005515 protein binding; GO:0051020 GTPase binding; GO:0005488 binding; GO:0019899 enzyme binding; ","K20173",null,null,"IPR019143; ","\"JNK/Rab-associated protein-1, N-terminal; \"\r"]
["Q5GLZ8","Probable E3 ubiquitin-protein ligase HERC4 OS=Homo sapiens OX=9606 GN=HERC4","HERC4",118.56,40.063,11.4,10,11,10,0.924,0.934,1.023,1.08,0.947,1.009,1.054,0.355,"nucleus\r","GO:0000003 reproduction; GO:0022414 reproductive process; GO:0048869 cellular developmental process; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0008152 metabolic process; GO:0044702 single organism reproductive process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009987 cellular process; GO:0032502 developmental process; GO:0016567 protein ubiquitination; GO:0048232 male gamete generation; GO:0007283 spermatogenesis; GO:0044763 single-organism cellular process; GO:0019953 sexual reproduction; GO:0070647 protein modification by small protein conjugation or removal; GO:0044238 primary metabolic process; GO:0032501 multicellular organismal process; GO:0007276 gamete generation; GO:0051704 multi-organism process; GO:0032504 multicellular organism reproduction; GO:0032446 protein modification by small protein conjugation; GO:0044767 single-organism developmental process; GO:0044703 multi-organism reproductive process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:0048609 multicellular organismal reproductive process; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0044452 nucleolar part; GO:0044424 intracellular part; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0005623 cell; GO:0001650 fibrillar center; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031974 membrane-enclosed lumen; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0019787 ubiquitin-like protein transferase activity; GO:0016740 transferase activity; GO:0003824 catalytic activity; GO:0004842 ubiquitin-protein transferase activity; ","K10615","HERC4; E3 ubiquitin-protein ligase HERC4 [EC:2.3.2.26]","hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human); ","IPR009091; IPR000569; ","Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II; HECT domain; \r"]
["Q5J8M3","ER membrane protein complex subunit 4 OS=Homo sapiens OX=9606 GN=EMC4","EMC4",20.086,3.5571,5.5,1,2,1,0.87,1.266,0.996,1.012,0.98,0.897,0.922,0.578,"cytoplasm\r","GO:0006457 protein folding; GO:0008219 cell death; GO:0006915 apoptotic process; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0034975 protein folding in endoplasmic reticulum; GO:0012501 programmed cell death; GO:0009987 cellular process; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0072546 ER membrane protein complex; GO:0044432 endoplasmic reticulum part; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0031227 intrinsic component of endoplasmic reticulum membrane; GO:0043227 membrane-bounded organelle; GO:0043234 protein complex; GO:0030176 integral component of endoplasmic reticulum membrane; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; "]
["Q5JRA6","Transport and Golgi organization protein 1 homolog OS=Homo sapiens OX=9606 GN=MIA3","MIA3",213.7,24.555,4.5,9,9,9,0.977,1.021,1.027,1.051,0.959,0.975,0.987,0.69,"endoplasmic reticulum\r","GO:0044085 cellular component biogenesis; GO:0030335 positive regulation of cell migration; GO:0035459 cargo loading into vesicle; GO:0040017 positive regulation of locomotion; GO:0044699 single-organism process; GO:0051668 localization within membrane; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0040013 negative regulation of locomotion; GO:0009611 response to wounding; GO:0051649 establishment of localization in cell; GO:0044872 lipoprotein localization; GO:0022607 cellular component assembly; GO:0032879 regulation of localization; GO:0065003 macromolecular complex assembly; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0051272 positive regulation of cellular component movement; GO:2000146 negative regulation of cell motility; GO:1902582 single-organism intracellular transport; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0032940 secretion by cell; GO:0002682 regulation of immune system process; GO:0002685 regulation of leukocyte migration; GO:0002687 positive regulation of leukocyte migration; GO:0051271 negative regulation of cellular component movement; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0007162 negative regulation of cell adhesion; GO:0090110 cargo loading into COPII-coated vesicle; GO:0048193 Golgi vesicle transport; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:2000147 positive regulation of cell motility; GO:0050896 response to stimulus; GO:1902578 single-organism localization; GO:2000145 regulation of cell motility; GO:1902580 single-organism cellular localization; GO:0009987 cellular process; GO:0034622 cellular macromolecular complex assembly; GO:0006950 response to stress; GO:0090114 COPII-coated vesicle budding; GO:0051270 regulation of cellular component movement; GO:0016192 vesicle-mediated transport; GO:0016050 vesicle organization; GO:0071702 organic substance transport; GO:0030334 regulation of cell migration; GO:0048518 positive regulation of biological process; GO:0042953 lipoprotein transport; GO:0030155 regulation of cell adhesion; GO:0051641 cellular localization; GO:0043933 macromolecular complex subunit organization; GO:0045184 establishment of protein localization; GO:0042060 wound healing; GO:0030336 negative regulation of cell migration; GO:0006996 organelle organization; GO:0002684 positive regulation of immune system process; GO:0006900 membrane budding; GO:0061024 membrane organization; GO:0051179 localization; GO:0040012 regulation of locomotion; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0006887 exocytosis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0098588 bounding membrane of organelle; GO:0031090 organelle membrane; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0000139 Golgi membrane; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0070971 endoplasmic reticulum exit site; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044432 endoplasmic reticulum part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0044431 Golgi apparatus part; GO:0005794 Golgi apparatus; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; ","GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0042954 lipoprotein transporter activity; GO:0008565 protein transporter activity; GO:0005488 binding; GO:0005215 transporter activity; ",{"$nulls":3},"IPR001452; IPR011511; ","SH3 domain; Variant SH3 domain; \r"]
["Q5JSL3","Dedicator of cytokinesis protein 11 OS=Homo sapiens OX=9606 GN=DOCK11","DOCK11",237.67,8.0788,1.6,4,4,4,1.062,0.959,0.988,0.999,0.925,1.03,0.982,0.695,"plasma membrane\r","GO:0044700 single organism signaling; GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0060491 regulation of cell projection assembly; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0051130 positive regulation of cellular component organization; GO:0009611 response to wounding; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0002313 mature B cell differentiation involved in immune response; GO:0044093 positive regulation of molecular function; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0002521 leukocyte differentiation; GO:0031346 positive regulation of cell projection organization; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0002335 mature B cell differentiation; GO:0002520 immune system development; GO:0007264 small GTPase mediated signal transduction; GO:0001776 leukocyte homeostasis; GO:0023052 signaling; GO:0030183 B cell differentiation; GO:0002312 B cell activation involved in immune response; GO:0032501 multicellular organismal process; GO:0048872 homeostasis of number of cells; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0065009 regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0050817 coagulation; GO:0048856 anatomical structure development; GO:0002260 lymphocyte homeostasis; GO:0002315 marginal zone B cell differentiation; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0002252 immune effector process; GO:0044087 regulation of cellular component biogenesis; GO:0031344 regulation of cell projection organization; GO:0050896 response to stimulus; GO:0007599 hemostasis; GO:0051489 regulation of filopodium assembly; GO:0030098 lymphocyte differentiation; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:0051345 positive regulation of hydrolase activity; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0001782 B cell homeostasis; GO:0042113 B cell activation; GO:0050878 regulation of body fluid levels; GO:0002285 lymphocyte activation involved in immune response; GO:0006950 response to stress; GO:0043547 positive regulation of GTPase activity; GO:0035556 intracellular signal transduction; GO:0048731 system development; GO:0002376 immune system process; GO:0046649 lymphocyte activation; GO:0002263 cell activation involved in immune response; GO:0048518 positive regulation of biological process; GO:0030097 hemopoiesis; GO:0048534 hematopoietic or lymphoid organ development; GO:0043085 positive regulation of catalytic activity; GO:0002366 leukocyte activation involved in immune response; GO:0051491 positive regulation of filopodium assembly; GO:0042060 wound healing; GO:0044767 single-organism developmental process; GO:0001775 cell activation; GO:0051128 regulation of cellular component organization; GO:0006955 immune response; GO:0044089 positive regulation of cellular component biogenesis; GO:0065007 biological regulation; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:0031267 small GTPase binding; GO:0017048 Rho GTPase binding; GO:0005085 guanyl-nucleotide exchange factor activity; GO:0017016 Ras GTPase binding; GO:0005488 binding; GO:0005088 Ras guanyl-nucleotide exchange factor activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0051020 GTPase binding; GO:0019899 enzyme binding; GO:0005089 Rho guanyl-nucleotide exchange factor activity; ",{"$nulls":3},"IPR021816; IPR010703; IPR027357; IPR011993; IPR027007; IPR016024; IPR001849; ","\"Dedicator of cytokinesis C/D, N-terminal; Dedicator of cytokinesis, C-terminal; DHR-2 domain; PH domain-like; DHR-1 domain; Armadillo-type fold; Pleckstrin homology domain; \"\r"]
["Q5JTB6","Placenta-specific protein 9 OS=Homo sapiens OX=9606 GN=PLAC9","PLAC9",10.309,2.7171,11.3,1,1,1,1.226,0.958,1.17,0.879,1.003,0.784,0.795,0.0921,"extracellular\r",null,"GO:0005576 extracellular region; ","GO:0005515 protein binding; GO:0005488 binding; "]
["Q5RI15","Cytochrome c oxidase assembly protein COX20, mitochondrial OS=Homo sapiens OX=9606 GN=COX20","COX20",13.291,6.9877,11.9,1,1,1,0.971,0.96,0.914,1.16,1.049,0.954,1.112,0.158,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0016043 cellular component organization; GO:0034622 cellular macromolecular complex assembly; GO:0071822 protein complex subunit organization; GO:0017004 cytochrome complex assembly; GO:0008535 respiratory chain complex IV assembly; GO:0055114 oxidation-reduction process; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0045333 cellular respiration; GO:0044237 cellular metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0097034 mitochondrial respiratory chain complex IV biogenesis; GO:0022607 cellular component assembly; GO:0009060 aerobic respiration; GO:0044710 single-organism metabolic process; GO:0006996 organelle organization; GO:0065003 macromolecular complex assembly; GO:0015980 energy derivation by oxidation of organic compounds; GO:0007005 mitochondrion organization; GO:0033617 mitochondrial respiratory chain complex IV assembly; GO:0070271 protein complex biogenesis; GO:0009987 cellular process; GO:0033108 mitochondrial respiratory chain complex assembly; GO:0006461 protein complex assembly; GO:0071840 cellular component organization or biogenesis; GO:0043623 cellular protein complex assembly; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044429 mitochondrial part; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005740 mitochondrial envelope; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0031975 envelope; GO:0043227 membrane-bounded organelle; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ",null,"K18184","COX20; cytochrome c oxidase assembly protein subunit 20","hsa04714 Thermogenesis - Homo sapiens (human); "]
["Q5RKV6","Exosome complex component MTR3 OS=Homo sapiens OX=9606 GN=EXOSC6","EXOSC6",28.235,11.774,14.7,3,5,3,0.948,0.954,0.911,1.14,1.035,1.026,1.138,0.025,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0002694 regulation of leukocyte activation; GO:0045191 regulation of isotype switching; GO:0065008 regulation of biological quality; GO:0022613 ribonucleoprotein complex biogenesis; GO:0016064 immunoglobulin mediated immune response; GO:0045321 leukocyte activation; GO:0010608 posttranscriptional regulation of gene expression; GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0044237 cellular metabolic process; GO:0045006 DNA deamination; GO:0043628 ncRNA 3'-end processing; GO:0008152 metabolic process; GO:0016075 rRNA catabolic process; GO:0071025 RNA surveillance; GO:0051240 positive regulation of multicellular organismal process; GO:0006364 rRNA processing; GO:0043170 macromolecule metabolic process; GO:0000018 regulation of DNA recombination; GO:0006396 RNA processing; GO:0045190 isotype switching; GO:0002443 leukocyte mediated immunity; GO:0080090 regulation of primary metabolic process; GO:0051054 positive regulation of DNA metabolic process; GO:0002639 positive regulation of immunoglobulin production; GO:0050864 regulation of B cell activation; GO:0044763 single-organism cellular process; GO:0042254 ribosome biogenesis; GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic; GO:0002520 immune system development; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0050776 regulation of immune response; GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0002889 regulation of immunoglobulin mediated immune response; GO:0034661 ncRNA catabolic process; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:0006402 mRNA catabolic process; GO:0002381 immunoglobulin production involved in immunoglobulin mediated immune response; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0002682 regulation of immune system process; GO:0002821 positive regulation of adaptive immune response; GO:0051094 positive regulation of developmental process; GO:0016071 mRNA metabolic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0006259 DNA metabolic process; GO:0016445 somatic diversification of immunoglobulins; GO:0002200 somatic diversification of immune receptors; GO:0048519 negative regulation of biological process; GO:0002562 somatic diversification of immune receptors via germline recombination within a single locus; GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0051239 regulation of multicellular organismal process; GO:0043487 regulation of RNA stability; GO:0019724 B cell mediated immunity; GO:0002204 somatic recombination of immunoglobulin genes involved in immune response; GO:0044270 cellular nitrogen compound catabolic process; GO:0050867 positive regulation of cell activation; GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'; GO:0002208 somatic diversification of immunoglobulins involved in immune response; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0016073 snRNA metabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0044248 cellular catabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0007275 multicellular organism development; GO:0002449 lymphocyte mediated immunity; GO:0050778 positive regulation of immune response; GO:0031125 rRNA 3'-end processing; GO:0002285 lymphocyte activation involved in immune response; GO:0071028 nuclear mRNA surveillance; GO:0048731 system development; GO:0071027 nuclear RNA surveillance; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0002263 cell activation involved in immune response; GO:0043144 snoRNA processing; GO:0002696 positive regulation of leukocyte activation; GO:0031325 positive regulation of cellular metabolic process; GO:0001775 cell activation; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0048584 positive regulation of response to stimulus; GO:0043412 macromolecule modification; GO:0006955 immune response; GO:0071051 polyadenylation-dependent snoRNA 3'-end processing; GO:0050793 regulation of developmental process; GO:0034472 snRNA 3'-end processing; GO:0002702 positive regulation of production of molecular mediator of immune response; GO:0044699 single-organism process; GO:0051249 regulation of lymphocyte activation; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0002250 adaptive immune response; GO:0002819 regulation of adaptive immune response; GO:1901361 organic cyclic compound catabolic process; GO:0002697 regulation of immune effector process; GO:0002708 positive regulation of lymphocyte mediated immunity; GO:0006310 DNA recombination; GO:0034475 U4 snRNA 3'-end processing; GO:0032502 developmental process; GO:0034470 ncRNA processing; GO:0016072 rRNA metabolic process; GO:0010468 regulation of gene expression; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0002700 regulation of production of molecular mediator of immune response; GO:0051251 positive regulation of lymphocyte activation; GO:0002312 B cell activation involved in immune response; GO:0010605 negative regulation of macromolecule metabolic process; GO:0016070 RNA metabolic process; GO:0006401 RNA catabolic process; GO:0050865 regulation of cell activation; GO:0050789 regulation of biological process; GO:0051052 regulation of DNA metabolic process; GO:0090304 nucleic acid metabolic process; GO:0002440 production of molecular mediator of immune response; GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; GO:0002705 positive regulation of leukocyte mediated immunity; GO:0019222 regulation of metabolic process; GO:0048856 anatomical structure development; GO:0002891 positive regulation of immunoglobulin mediated immune response; GO:2000026 regulation of multicellular organismal development; GO:0031123 RNA 3'-end processing; GO:0006725 cellular aromatic compound metabolic process; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0050896 response to stimulus; GO:0002706 regulation of lymphocyte mediated immunity; GO:0071704 organic substance metabolic process; GO:0016180 snRNA processing; GO:0050871 positive regulation of B cell activation; GO:0034641 cellular nitrogen compound metabolic process; GO:0031126 snoRNA 3'-end processing; GO:0002714 positive regulation of B cell mediated immunity; GO:0009987 cellular process; GO:0006304 DNA modification; GO:0042113 B cell activation; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0016444 somatic cell DNA recombination; GO:0016447 somatic recombination of immunoglobulin gene segments; GO:0010629 negative regulation of gene expression; GO:0002699 positive regulation of immune effector process; GO:0002712 regulation of B cell mediated immunity; GO:0006807 nitrogen compound metabolic process; GO:0046649 lymphocyte activation; GO:0016074 snoRNA metabolic process; GO:0048518 positive regulation of biological process; GO:0043488 regulation of mRNA stability; GO:0002703 regulation of leukocyte mediated immunity; GO:0002366 leukocyte activation involved in immune response; GO:0002377 immunoglobulin production; GO:0045830 positive regulation of isotype switching; GO:0044767 single-organism developmental process; GO:0002637 regulation of immunoglobulin production; GO:0002684 positive regulation of immune system process; GO:0009057 macromolecule catabolic process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0010467 gene expression; GO:0045911 positive regulation of DNA recombination; GO:0034660 ncRNA metabolic process; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0000176 nuclear exosome (RNase complex); GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0000177 cytoplasmic exosome (RNase complex); GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:1905354 exoribonuclease complex; GO:0043226 organelle; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; GO:0000178 exosome (RNase complex); ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; ","K12587","MTR3; exosome complex component MTR3","hsa03018 RNA degradation - Homo sapiens (human); ","IPR015847; IPR001247; IPR020568; IPR027408; ","\"Exoribonuclease, phosphorolytic domain 2; Exoribonuclease, phosphorolytic domain 1; Ribosomal protein S5 domain 2-type fold; PNPase/RNase PH domain; \"\r"]
["Q5SRE7","Phytanoyl-CoA dioxygenase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PHYHD1","PHYHD1",32.41,5.0389,9.3,2,2,2,1.207,1.057,1.166,0.868,0.876,0.851,0.757,0.0024,"cytoplasm\r","GO:0044699 single-organism process; GO:0008152 metabolic process; GO:0055114 oxidation-reduction process; GO:0044710 single-organism metabolic process; ",null,"GO:0003824 catalytic activity; GO:0051213 dioxygenase activity; GO:0005488 binding; GO:0043167 ion binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0016491 oxidoreductase activity; "]
["Q5SYB0","FERM and PDZ domain-containing protein 1 OS=Homo sapiens OX=9606 GN=FRMPD1","FRMPD1",173.43,2.7081,0.4,1,4,1,1.174,1.275,1.473,0.742,0.724,0.655,0.541,1.32E-3,"nucleus\r",null,"GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005856 cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR019748; IPR019749; IPR011993; IPR029071; IPR001478; IPR014352; IPR000299; ","\"FERM central domain; Band 4.1 domain; PH domain-like; Ubiquitin-related domain; PDZ domain; FERM/acyl-CoA-binding protein, 3-helical bundle; FERM domain; \"\r"]
["Q5T160","Probable arginine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=RARS2","RARS2",65.505,14.085,2.4,1,1,1,0.878,0.959,0.791,1.138,1.067,1.164,1.282,0.0151,"mitochondria\r","GO:0006518 peptide metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0043039 tRNA aminoacylation; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0006418 tRNA aminoacylation for protein translation; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0006412 translation; GO:0009987 cellular process; GO:0043043 peptide biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0032543 mitochondrial translation; GO:0043603 cellular amide metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0006420 arginyl-tRNA aminoacylation; GO:0044249 cellular biosynthetic process; GO:0016070 RNA metabolic process; GO:0006399 tRNA metabolic process; GO:0090304 nucleic acid metabolic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0044710 single-organism metabolic process; GO:0043038 amino acid activation; GO:0019752 carboxylic acid metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0006082 organic acid metabolic process; GO:0034660 ncRNA metabolic process; GO:0043436 oxoacid metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds; GO:0003723 RNA binding; GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0016875 ligase activity, forming carbon-oxygen bonds; GO:0016874 ligase activity; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0000166 nucleotide binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0032550 purine ribonucleoside binding; GO:0004814 arginine-tRNA ligase activity; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0004812 aminoacyl-tRNA ligase activity; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K01887","RARS; arginyl-tRNA synthetase [EC:6.1.1.19]","hsa00970 Aminoacyl-tRNA biosynthesis - Homo sapiens (human); ","IPR008909; IPR014729; IPR005148; IPR009080; ","\"DALR anticodon binding; Rossmann-like alpha/beta/alpha sandwich fold; Arginyl tRNA synthetase N-terminal domain; Aminoacyl-tRNA synthetase, class Ia, anticodon-binding; \"\r"]
["Q5T447","E3 ubiquitin-protein ligase HECTD3 OS=Homo sapiens OX=9606 GN=HECTD3","HECTD3",97.112,9.774,1.6,1,3,1,0.853,0.948,1.068,1.125,0.909,1.098,1.092,0.403,"cytoplasm\r","GO:0043632 modification-dependent macromolecule catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0016567 protein ubiquitination; GO:0019941 modification-dependent protein catabolic process; GO:0044267 cellular protein metabolic process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0010498 proteasomal protein catabolic process; GO:0071704 organic substance metabolic process; GO:1901575 organic substance catabolic process; GO:0008152 metabolic process; GO:0032446 protein modification by small protein conjugation; GO:0030163 protein catabolic process; GO:0009057 macromolecule catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0044248 cellular catabolic process; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0006508 proteolysis; GO:0006464 cellular protein modification process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:0009056 catabolic process; GO:0009987 cellular process; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0048471 perinuclear region of cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:0000149 SNARE binding; GO:0019787 ubiquitin-like protein transferase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0004842 ubiquitin-protein transferase activity; GO:0005515 protein binding; GO:0019905 syntaxin binding; GO:0016740 transferase activity; ","K12233",null,null,"IPR004939; IPR000569; IPR008979; ","APC10/DOC domain; HECT domain; Galactose-binding domain-like; \r"]
["Q5T619","Zinc finger protein 648 OS=Homo sapiens OX=9606 GN=ZNF648","ZNF648",62.34,2.4211,2.1,1,15,1,0.838,0.84,0.877,1.14,1.166,1.151,1.353,4.4e-05,"nucleus\r","GO:0050794 regulation of cellular process; GO:0006725 cellular aromatic compound metabolic process; GO:0097659 nucleic acid-templated transcription; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0006355 regulation of transcription, DNA-templated; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0044238 primary metabolic process; GO:0051252 regulation of RNA metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0034645 cellular macromolecule biosynthetic process; GO:0090304 nucleic acid metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006351 transcription, DNA-templated; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0010467 gene expression; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0065007 biological regulation; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003677 DNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0043167 ion binding; GO:0043169 cation binding; GO:0046872 metal ion binding; ",{"$nulls":3},"IPR015880; IPR007087; IPR013087; ","\"Zinc finger, C2H2-like; Zinc finger, C2H2; Zinc finger C2H2-type/integrase DNA-binding domain; \"\r"]
["Q5TAP6","U3 small nucleolar RNA-associated protein 14 homolog C OS=Homo sapiens OX=9606 GN=UTP14C","UTP14C",87.187,4.9543,1.7,1,1,1,0.807,0.865,0.784,1.115,1.184,1.229,1.436,0.00088,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0000003 reproduction; GO:0044707 single-multicellular organism process; GO:0022613 ribonucleoprotein complex biogenesis; GO:0006725 cellular aromatic compound metabolic process; GO:0022414 reproductive process; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0030154 cell differentiation; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0006364 rRNA processing; GO:0044702 single organism reproductive process; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0043170 macromolecule metabolic process; GO:0009987 cellular process; GO:0032502 developmental process; GO:0034470 ncRNA processing; GO:0006396 RNA processing; GO:0016072 rRNA metabolic process; GO:0048232 male gamete generation; GO:0042274 ribosomal small subunit biogenesis; GO:0007283 spermatogenesis; GO:0044763 single-organism cellular process; GO:0019953 sexual reproduction; GO:0042254 ribosome biogenesis; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0051321 meiotic cell cycle; GO:0044238 primary metabolic process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0007276 gamete generation; GO:0032504 multicellular organism reproduction; GO:0016070 RNA metabolic process; GO:0090304 nucleic acid metabolic process; GO:0044767 single-organism developmental process; GO:0044703 multi-organism reproductive process; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0048856 anatomical structure development; GO:0034660 ncRNA metabolic process; GO:0048609 multicellular organismal reproductive process; GO:0030490 maturation of SSU-rRNA; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0030684 preribosome; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1990904 ribonucleoprotein complex; GO:0032040 small-subunit processome; GO:0043227 membrane-bounded organelle; GO:0030529 intracellular ribonucleoprotein complex; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0005488 binding; ","K14567","UTP14; U3 small nucleolar RNA-associated protein 14","hsa03008 Ribosome biogenesis in eukaryotes - Homo sapiens (human); "]
["Q5TFE4","5'-nucleotidase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=NT5DC1","NT5DC1",51.844,26.25,8.4,3,5,3,0.93,0.916,0.94,1.06,1.063,1.044,1.137,0.000162,"cytoplasm\r","GO:0008152 metabolic process; GO:0016311 dephosphorylation; GO:0044237 cellular metabolic process; GO:0006793 phosphorus metabolic process; GO:0009987 cellular process; GO:0006796 phosphate-containing compound metabolic process; ",null,"GO:0008253 5'-nucleotidase activity; GO:0042578 phosphoric ester hydrolase activity; GO:0003824 catalytic activity; GO:0016791 phosphatase activity; GO:0008252 nucleotidase activity; GO:0005488 binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0043167 ion binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0016787 hydrolase activity; ",{"$nulls":3},"IPR023214; ","HAD-like domain; \r"]
["Q5TGY3","AT-hook DNA-binding motif-containing protein 1 OS=Homo sapiens OX=9606 GN=AHDC1","AHDC1",168.35,1.77,0.6,1,1,1,1.324,1.079,1.3,0.759,0.789,0.783,0.629,2.3E-3,"nucleus\r",null,null,"GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003677 DNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; ",{"$nulls":3},"IPR032757; ","Domain of unknown function DUF4683; \r"]
["Q5U3C3","Transmembrane protein 164 OS=Homo sapiens OX=9606 GN=TMEM164","TMEM164",33.507,6.834,6.1,1,1,1,1.555,1.872,1.623,0.343,0.312,0.395,0.208,5.96e-05,"plasma membrane\r",null,"GO:0031224 intrinsic component of membrane; GO:0016020 membrane; GO:0016021 integral component of membrane; GO:0044425 membrane part; "]
["Q5VTE0","Putative elongation factor 1-alpha-like 3 OS=Homo sapiens OX=9606 GN=EEF1A1P5","EEF1A1P5",50.184,163.73,47.8,24,72,15,0.831,0.865,0.909,1.143,1.129,1.058,1.278,0.00224,"cytoplasm\r","GO:0006518 peptide metabolic process; GO:0006414 translational elongation; GO:0043043 peptide biosynthetic process; GO:0044267 cellular protein metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0009058 biosynthetic process; GO:0043603 cellular amide metabolic process; GO:0044238 primary metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:1901576 organic substance biosynthetic process; GO:0044237 cellular metabolic process; GO:0044249 cellular biosynthetic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0010467 gene expression; GO:0043170 macromolecule metabolic process; GO:0043604 amide biosynthetic process; GO:0019538 protein metabolic process; GO:0006412 translation; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:1901564 organonitrogen compound metabolic process; ","GO:0043229 intracellular organelle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:1901265 nucleoside phosphate binding; GO:0003746 translation elongation factor activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0003924 GTPase activity; GO:0043168 anion binding; GO:0019001 guanyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003723 RNA binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0008135 translation factor activity, RNA binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003676 nucleic acid binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0032561 guanyl ribonucleotide binding; GO:0036094 small molecule binding; ","K03231","EEF1A; elongation factor 1-alpha","hsa05134 Legionellosis - Homo sapiens (human); hsa03013 RNA transport - Homo sapiens (human); ","IPR004160; IPR004161; IPR009001; IPR027417; IPR000795; IPR009000; ","\"Translation elongation factor EFTu/EF1A, C-terminal; Translation elongation factor EFTu-like, domain 2; Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal; P-loop containing nucleoside triphosphate hydrolase; Transcription factor, GTP-binding domain; Translation protein, beta-barrel domain; \"\r"]
["Q5VW32","BRO1 domain-containing protein BROX OS=Homo sapiens OX=9606 GN=BROX","BROX",46.476,15.991,13.1,5,7,5,1.026,1.011,0.968,0.957,1.006,1.04,0.999,0.976,"mitochondria\r",null,"GO:0016020 membrane; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ",{"$nulls":4},"IPR004328; ","BRO1 domain; \r"]
["Q5VWC8","Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4 OS=Homo sapiens OX=9606 GN=HACD4","HACD4",27.52,2.632,3.9,1,2,1,0.989,1.117,1.129,0.929,0.93,0.924,0.86,0.0729,"mitochondria\r","GO:0044711 single-organism biosynthetic process; GO:0016053 organic acid biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044255 cellular lipid metabolic process; GO:0006631 fatty acid metabolic process; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0006633 fatty acid biosynthetic process; GO:1901576 organic substance biosynthetic process; GO:0042761 very long-chain fatty acid biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0071704 organic substance metabolic process; GO:0008610 lipid biosynthetic process; GO:0000038 very long-chain fatty acid metabolic process; GO:0046394 carboxylic acid biosynthetic process; GO:0008152 metabolic process; GO:0044710 single-organism metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0044283 small molecule biosynthetic process; GO:0030497 fatty acid elongation; GO:0032787 monocarboxylic acid metabolic process; GO:0006082 organic acid metabolic process; GO:0009987 cellular process; GO:0072330 monocarboxylic acid biosynthetic process; GO:0043436 oxoacid metabolic process; GO:0006629 lipid metabolic process; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044432 endoplasmic reticulum part; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; ","GO:0018812 3-hydroxyacyl-CoA dehydratase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0102344 3-hydroxy-behenoyl-CoA dehydratase activity; GO:0016829 lyase activity; GO:0005515 protein binding; GO:0016836 hydro-lyase activity; GO:0102345 3-hydroxy-lignoceroyl-CoA dehydratase activity; GO:0019899 enzyme binding; GO:0016835 carbon-oxygen lyase activity; ","K10703","PHS1; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134]","hsa01040 Biosynthesis of unsaturated fatty acids - Homo sapiens (human); hsa01212 Fatty acid metabolism - Homo sapiens (human); hsa00062 Fatty acid elongation - Homo sapiens (human); "]
["Q5VYY1","Ankyrin repeat domain-containing protein 22 OS=Homo sapiens OX=9606 GN=ANKRD22","ANKRD22",21.848,7.1456,11,2,2,2,0.808,0.724,0.862,1.055,1.241,1.283,1.495,0.0071,"cytoplasm\r",null,null,"GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR020683; ","Ankyrin repeat-containing domain; \r"]
["Q5ZPR3","CD276 antigen OS=Homo sapiens OX=9606 GN=CD276","CD276",57.235,12.141,7.1,2,3,2,0.978,1.275,1.031,1.126,0.834,0.791,0.838,0.252,"extracellular\r","GO:0050863 regulation of T cell activation; GO:0002694 regulation of leukocyte activation; GO:0032944 regulation of mononuclear cell proliferation; GO:0045321 leukocyte activation; GO:0042108 positive regulation of cytokine biosynthetic process; GO:0009891 positive regulation of biosynthetic process; GO:0044699 single-organism process; GO:0051249 regulation of lymphocyte activation; GO:0042110 T cell activation; GO:0050671 positive regulation of lymphocyte proliferation; GO:0032946 positive regulation of mononuclear cell proliferation; GO:0051240 positive regulation of multicellular organismal process; GO:0009893 positive regulation of metabolic process; GO:0070663 regulation of leukocyte proliferation; GO:0042035 regulation of cytokine biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0050670 regulation of lymphocyte proliferation; GO:0051251 positive regulation of lymphocyte activation; GO:0045078 positive regulation of interferon-gamma biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0050776 regulation of immune response; GO:0050789 regulation of biological process; GO:0050865 regulation of cell activation; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0019222 regulation of metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0002682 regulation of immune system process; GO:0050794 regulation of cellular process; GO:0042127 regulation of cell proliferation; GO:0042102 positive regulation of T cell proliferation; GO:0060255 regulation of macromolecule metabolic process; GO:0001819 positive regulation of cytokine production; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:0032729 positive regulation of interferon-gamma production; GO:0050867 positive regulation of cell activation; GO:0009889 regulation of biosynthetic process; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:0009987 cellular process; GO:0032649 regulation of interferon-gamma production; GO:0045785 positive regulation of cell adhesion; GO:0022409 positive regulation of cell-cell adhesion; GO:0042129 regulation of T cell proliferation; GO:0002376 immune system process; GO:0046649 lymphocyte activation; GO:0008283 cell proliferation; GO:0010556 regulation of macromolecule biosynthetic process; GO:1903039 positive regulation of leukocyte cell-cell adhesion; GO:0048518 positive regulation of biological process; GO:0022407 regulation of cell-cell adhesion; GO:0030155 regulation of cell adhesion; GO:0002696 positive regulation of leukocyte activation; GO:0070665 positive regulation of leukocyte proliferation; GO:0051247 positive regulation of protein metabolic process; GO:0050870 positive regulation of T cell activation; GO:0051246 regulation of protein metabolic process; GO:0002684 positive regulation of immune system process; GO:0031325 positive regulation of cellular metabolic process; GO:0001775 cell activation; GO:0001817 regulation of cytokine production; GO:0006955 immune response; GO:0031328 positive regulation of cellular biosynthetic process; GO:0045072 regulation of interferon-gamma biosynthetic process; GO:0065007 biological regulation; GO:0008284 positive regulation of cell proliferation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0009897 external side of plasma membrane; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0044459 plasma membrane part; GO:0044464 cell part; GO:0044425 membrane part; GO:1903561 extracellular vesicle; GO:0009986 cell surface; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0098552 side of membrane; ","GO:0005515 protein binding; GO:0005102 receptor binding; GO:0005488 binding; ","K06746","B7H3; immune costimulatory protein B7-H3","hsa04514 Cell adhesion molecules (CAMs) - Homo sapiens (human); ","IPR003598; IPR007110; IPR013783; IPR013106; IPR003599; IPR003597; ","Immunoglobulin subtype 2; Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin V-set domain; Immunoglobulin subtype; Immunoglobulin C1-set; \r"]
["Q63HR2","Tensin-2 OS=Homo sapiens OX=9606 GN=TNS2","TNS2",152.58,21.579,5.5,7,7,5,1.042,1.093,0.917,0.975,1.065,0.923,0.971,0.691,"nucleus\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0044707 single-multicellular organism process; GO:0065008 regulation of biological quality; GO:0042127 regulation of cell proliferation; GO:0044236 multicellular organism metabolic process; GO:0044267 cellular protein metabolic process; GO:0014850 response to muscle activity; GO:0044699 single-organism process; GO:0072001 renal system development; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0048871 multicellular organismal homeostasis; GO:0006796 phosphate-containing compound metabolic process; GO:0008285 negative regulation of cell proliferation; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0035264 multicellular organism growth; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0007275 multicellular organism development; GO:0044259 multicellular organismal macromolecule metabolic process; GO:0009987 cellular process; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0001822 kidney development; GO:0035556 intracellular signal transduction; GO:0048731 system development; GO:0044763 single-organism cellular process; GO:0019725 cellular homeostasis; GO:0006470 protein dephosphorylation; GO:0023052 signaling; GO:0044238 primary metabolic process; GO:0016311 dephosphorylation; GO:0032501 multicellular organismal process; GO:0048513 animal organ development; GO:0001655 urogenital system development; GO:0050789 regulation of biological process; GO:0014823 response to activity; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0044767 single-organism developmental process; GO:0032963 collagen metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0048589 developmental growth; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:0040007 growth; GO:0048856 anatomical structure development; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0044464 cell part; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0005912 adherens junction; GO:0070161 anchoring junction; GO:0030055 cell-substrate junction; GO:0005623 cell; GO:0005886 plasma membrane; GO:0005924 cell-substrate adherens junction; ","GO:0042578 phosphoric ester hydrolase activity; GO:0003824 catalytic activity; GO:0016791 phosphatase activity; GO:0005488 binding; GO:0043167 ion binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0004721 phosphoprotein phosphatase activity; GO:0019900 kinase binding; GO:0019899 enzyme binding; ","K18080",null,null,"IPR013625; IPR033929; IPR029023; IPR006020; IPR002219; IPR029021; IPR000980; IPR011993; IPR014020; IPR000008; ","\"Tensin/EPS8 phosphotyrosine-binding domain; Tensin, phosphotyrosine-binding domain; Tensin phosphatase, lipid phosphatase domain; PTB/PI domain; Protein kinase C-like, phorbol ester/diacylglycerol-binding domain; Protein-tyrosine phosphatase-like; SH2 domain; PH domain-like; Tensin phosphatase, C2 domain; C2 domain; \"\r"]
["Q63ZY3","KN motif and ankyrin repeat domain-containing protein 2 OS=Homo sapiens OX=9606 GN=KANK2","KANK2",91.173,64.216,18.2,14,18,14,1.097,1.107,1.083,0.864,0.908,0.927,0.821,0.000824,"nucleus\r","GO:2000045 regulation of G1/S transition of mitotic cell cycle; GO:1902807 negative regulation of cell cycle G1/S phase transition; GO:0010941 regulation of cell death; GO:0070563 negative regulation of vitamin D receptor signaling pathway; GO:0009968 negative regulation of signal transduction; GO:0097659 nucleic acid-templated transcription; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0032104 regulation of response to extracellular stimulus; GO:0051253 negative regulation of RNA metabolic process; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0008285 negative regulation of cell proliferation; GO:2001141 regulation of RNA biosynthetic process; GO:0045930 negative regulation of mitotic cell cycle; GO:0008152 metabolic process; GO:0010646 regulation of cell communication; GO:1901991 negative regulation of mitotic cell cycle phase transition; GO:0006915 apoptotic process; GO:1902806 regulation of cell cycle G1/S phase transition; GO:0032102 negative regulation of response to external stimulus; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0043170 macromolecule metabolic process; GO:0051726 regulation of cell cycle; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:2000134 negative regulation of G1/S transition of mitotic cell cycle; GO:0000122 negative regulation of transcription from RNA polymerase II promoter; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0032107 regulation of response to nutrient levels; GO:0032774 RNA biosynthetic process; GO:0032108 negative regulation of response to nutrient levels; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0010948 negative regulation of cell cycle process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:1902679 negative regulation of RNA biosynthetic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0033143 regulation of intracellular steroid hormone receptor signaling pathway; GO:0060548 negative regulation of cell death; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0007346 regulation of mitotic cell cycle; GO:0045786 negative regulation of cell cycle; GO:0043069 negative regulation of programmed cell death; GO:0042127 regulation of cell proliferation; GO:0006725 cellular aromatic compound metabolic process; GO:1901988 negative regulation of cell cycle phase transition; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0043067 regulation of programmed cell death; GO:0033144 negative regulation of intracellular steroid hormone receptor signaling pathway; GO:0031324 negative regulation of cellular metabolic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0071704 organic substance metabolic process; GO:0045892 negative regulation of transcription, DNA-templated; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901987 regulation of cell cycle phase transition; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0070562 regulation of vitamin D receptor signaling pathway; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0009987 cellular process; GO:0009966 regulation of signal transduction; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0006807 nitrogen compound metabolic process; GO:0032101 regulation of response to external stimulus; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0048585 negative regulation of response to stimulus; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0051252 regulation of RNA metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway; GO:0009890 negative regulation of biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0033146 regulation of intracellular estrogen receptor signaling pathway; GO:0008219 cell death; GO:0032105 negative regulation of response to extracellular stimulus; GO:0010467 gene expression; GO:0031327 negative regulation of cellular biosynthetic process; GO:0012501 programmed cell death; GO:0065007 biological regulation; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR020683; ","Ankyrin repeat-containing domain; \r"]
["Q687X5","Metalloreductase STEAP4 OS=Homo sapiens OX=9606 GN=STEAP4","STEAP4",51.981,30.582,14.2,5,5,5,0.884,0.939,0.92,1.082,1.101,1,1.16,0.0127,"plasma membrane\r","GO:0065008 regulation of biological quality; GO:0055076 transition metal ion homeostasis; GO:0030001 metal ion transport; GO:0033216 ferric iron import; GO:0048869 cellular developmental process; GO:0055072 iron ion homeostasis; GO:0044699 single-organism process; GO:0006826 iron ion transport; GO:0097459 iron ion import into cell; GO:0051234 establishment of localization; GO:0000041 transition metal ion transport; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:0008152 metabolic process; GO:0006812 cation transport; GO:0055080 cation homeostasis; GO:0098659 inorganic cation import into cell; GO:0055065 metal ion homeostasis; GO:0015677 copper ion import; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0032502 developmental process; GO:0099587 inorganic ion import into cell; GO:0050801 ion homeostasis; GO:0015682 ferric iron transport; GO:0055114 oxidation-reduction process; GO:0006825 copper ion transport; GO:0044763 single-organism cellular process; GO:0098771 inorganic ion homeostasis; GO:0098657 import into cell; GO:0097286 iron ion import; GO:0097461 ferric iron import into cell; GO:0006810 transport; GO:0072512 trivalent inorganic cation transport; GO:0044767 single-organism developmental process; GO:0044710 single-organism metabolic process; GO:0006811 ion transport; GO:0045444 fat cell differentiation; GO:0051179 localization; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0031226 intrinsic component of plasma membrane; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0008823 cupric reductase activity; GO:0016722 oxidoreductase activity, oxidizing metal ions; GO:0052851 ferric-chelate reductase (NADPH) activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0016723 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor; GO:0016491 oxidoreductase activity; ","K19876",null,null,"IPR028939; IPR016040; IPR013130; ","\"Pyrroline-5-carboxylate reductase, catalytic, N-terminal; NAD(P)-binding domain; Ferric reductase transmembrane component-like domain; \"\r"]
["Q68CP4","Heparan-alpha-glucosaminide N-acetyltransferase OS=Homo sapiens OX=9606 GN=HGSNAT","HGSNAT",73.293,3.1809,2.1,1,1,1,0.994,1.079,0.993,0.894,0.979,1.07,0.96,0.506,"plasma membrane\r","GO:0044085 cellular component biogenesis; GO:0016043 cellular component organization; GO:0045321 leukocyte activation; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0006026 aminoglycan catabolic process; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0051259 protein oligomerization; GO:0071704 organic substance metabolic process; GO:0030203 glycosaminoglycan metabolic process; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:1901135 carbohydrate derivative metabolic process; GO:0043170 macromolecule metabolic process; GO:0036230 granulocyte activation; GO:0006022 aminoglycan metabolic process; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0007041 lysosomal transport; GO:0002443 leukocyte mediated immunity; GO:0071822 protein complex subunit organization; GO:0016192 vesicle-mediated transport; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:1901136 carbohydrate derivative catabolic process; GO:0002376 immune system process; GO:0043312 neutrophil degranulation; GO:0002263 cell activation involved in immune response; GO:0006027 glycosaminoglycan catabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0043933 macromolecular complex subunit organization; GO:0006810 transport; GO:0002366 leukocyte activation involved in immune response; GO:1901575 organic substance catabolic process; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:1901565 organonitrogen compound catabolic process; GO:0007034 vacuolar transport; GO:0032940 secretion by cell; GO:0009057 macromolecule catabolic process; GO:0001775 cell activation; GO:0043299 leukocyte degranulation; GO:0070271 protein complex biogenesis; GO:0006955 immune response; GO:0051179 localization; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; GO:1901564 organonitrogen compound metabolic process; GO:0006887 exocytosis; ","GO:0016020 membrane; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070821 tertiary granule membrane; GO:0005765 lysosomal membrane; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0098805 whole membrane; GO:0005764 lysosome; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0035579 specific granule membrane; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0070820 tertiary granule; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0098852 lytic vacuole membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0030667 secretory granule membrane; GO:0044437 vacuolar part; GO:0042581 specific granule; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0044444 cytoplasmic part; ","GO:0015019 heparan-alpha-glucosaminide N-acetyltransferase activity; GO:0016746 transferase activity, transferring acyl groups; GO:0008080 N-acetyltransferase activity; GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups; GO:0016740 transferase activity; GO:0003824 catalytic activity; GO:0016407 acetyltransferase activity; GO:0016410 N-acyltransferase activity; ","K10532","HGSNAT; heparan-alpha-glucosaminide N-acetyltransferase [EC:2.3.1.78]","hsa04142 Lysosome - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00531 Glycosaminoglycan degradation - Homo sapiens (human); ","IPR012429; ","Domain of unknown function DUF1624; \r"]
["Q68E01","Integrator complex subunit 3 OS=Homo sapiens OX=9606 GN=INTS3","INTS3",118.07,18.221,4.3,3,3,3,1.023,1.176,1.09,0.687,1.042,0.994,0.828,0.213,"cytoplasm\r","GO:0042795 snRNA transcription from RNA polymerase II promoter; GO:0097659 nucleic acid-templated transcription; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0045930 negative regulation of mitotic cell cycle; GO:0008152 metabolic process; GO:0000075 cell cycle checkpoint; GO:0009314 response to radiation; GO:0043170 macromolecule metabolic process; GO:0051726 regulation of cell cycle; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0016070 RNA metabolic process; GO:0009301 snRNA transcription; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0044260 cellular macromolecule metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0007346 regulation of mitotic cell cycle; GO:0045786 negative regulation of cell cycle; GO:0006725 cellular aromatic compound metabolic process; GO:0009628 response to abiotic stimulus; GO:0006259 DNA metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:1903047 mitotic cell cycle process; GO:0071704 organic substance metabolic process; GO:0016180 snRNA processing; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0098781 ncRNA transcription; GO:0016073 snRNA metabolic process; GO:0007093 mitotic cell cycle checkpoint; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006950 response to stress; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0006974 cellular response to DNA damage stimulus; GO:0010212 response to ionizing radiation; GO:0006281 DNA repair; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0006366 transcription from RNA polymerase II promoter; GO:0010467 gene expression; GO:0022402 cell cycle process; GO:0034660 ncRNA metabolic process; GO:0007049 cell cycle; GO:0065007 biological regulation; ","GO:0061695 transferase complex, transferring phosphorus-containing groups; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0032039 integrator complex; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0055029 nuclear DNA-directed RNA polymerase complex; GO:0000428 DNA-directed RNA polymerase complex; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0070876 SOSS complex; GO:0030880 RNA polymerase complex; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:1990234 transferase complex; GO:0016591 DNA-directed RNA polymerase II, holoenzyme; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0043234 protein complex; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0005488 binding; ","K13140"]
["Q69YN4","Protein virilizer homolog OS=Homo sapiens OX=9606 GN=VIRMA","VIRMA",202.02,2.0015,0.5,1,1,1,0.874,0.859,0.839,1.047,1.168,1.199,1.327,0.00286,"nucleus\r","GO:0006396 RNA processing; GO:0006725 cellular aromatic compound metabolic process; GO:0016556 mRNA modification; GO:0080009 mRNA methylation; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:0009451 RNA modification; GO:0044237 cellular metabolic process; GO:0032259 methylation; GO:0071704 organic substance metabolic process; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:0008152 metabolic process; GO:0090304 nucleic acid metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0043414 macromolecule methylation; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0034641 cellular nitrogen compound metabolic process; GO:0001510 RNA methylation; GO:0043170 macromolecule metabolic process; GO:0043412 macromolecule modification; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0016071 mRNA metabolic process; ","GO:0043229 intracellular organelle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; ",{"$nulls":3},"IPR016024; IPR031801; ","\"Armadillo-type fold; Virilizer, N-terminal; \"\r"]
["Q6DD87","Zinc finger protein 787 OS=Homo sapiens OX=9606 GN=ZNF787","ZNF787",40.428,6.3378,3.9,1,1,1,0.913,0.92,0.876,1.14,1.068,1.083,1.215,1.48E-3,"nucleus\r","GO:0050794 regulation of cellular process; GO:0006725 cellular aromatic compound metabolic process; GO:0097659 nucleic acid-templated transcription; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0006355 regulation of transcription, DNA-templated; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0044238 primary metabolic process; GO:0051252 regulation of RNA metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0034645 cellular macromolecule biosynthetic process; GO:0090304 nucleic acid metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006351 transcription, DNA-templated; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0010467 gene expression; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0065007 biological regulation; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003677 DNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0043167 ion binding; GO:0043169 cation binding; GO:0046872 metal ion binding; ",{"$nulls":3},"IPR015880; IPR007087; IPR013087; ","\"Zinc finger, C2H2-like; Zinc finger, C2H2; Zinc finger C2H2-type/integrase DNA-binding domain; \"\r"]
["Q6DKJ4","Nucleoredoxin OS=Homo sapiens OX=9606 GN=NXN","NXN",48.392,31.721,5.5,1,1,1,0.94,0.888,0.925,1.079,1.109,1.057,1.179,0.00168,"nucleus\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0009968 negative regulation of signal transduction; GO:0007166 cell surface receptor signaling pathway; GO:0023051 regulation of signaling; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0031400 negative regulation of protein modification process; GO:0031396 regulation of protein ubiquitination; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0098869 cellular oxidant detoxification; GO:0016055 Wnt signaling pathway; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0030178 negative regulation of Wnt signaling pathway; GO:0080090 regulation of primary metabolic process; GO:0055114 oxidation-reduction process; GO:0009636 response to toxic substance; GO:0044763 single-organism cellular process; GO:0019725 cellular homeostasis; GO:0023052 signaling; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0198738 cell-cell signaling by wnt; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0007267 cell-cell signaling; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0044710 single-organism metabolic process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0048583 regulation of response to stimulus; GO:0019222 regulation of metabolic process; GO:0098754 detoxification; GO:0048856 anatomical structure development; GO:0050794 regulation of cellular process; GO:0072359 circulatory system development; GO:0044707 single-multicellular organism process; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:0060255 regulation of macromolecule metabolic process; GO:0031399 regulation of protein modification process; GO:0045454 cell redox homeostasis; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:0023057 negative regulation of signaling; GO:1990748 cellular detoxification; GO:0010648 negative regulation of cell communication; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0009966 regulation of signal transduction; GO:0031397 negative regulation of protein ubiquitination; GO:0048731 system development; GO:0072358 cardiovascular system development; GO:0048585 negative regulation of response to stimulus; GO:0009892 negative regulation of metabolic process; GO:1903321 negative regulation of protein modification by small protein conjugation or removal; GO:0030111 regulation of Wnt signaling pathway; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0065007 biological regulation; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:0015036 disulfide oxidoreductase activity; GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:0003824 catalytic activity; GO:0004791 thioredoxin-disulfide reductase activity; GO:0047134 protein-disulfide reductase activity; GO:0016667 oxidoreductase activity, acting on a sulfur group of donors; GO:0016209 antioxidant activity; GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor; GO:0016491 oxidoreductase activity; ","K17609",null,null,"IPR013766; IPR012336; ","Thioredoxin domain; Thioredoxin-like fold; \r"]
["Q6E213","Acyl-CoA wax alcohol acyltransferase 2 OS=Homo sapiens OX=9606 GN=AWAT2","AWAT2",38.093,5.7156,6,2,2,2,1.141,1.173,1.203,0.821,0.847,0.843,0.714,4.45e-05,"cytoplasm\r","GO:0036155 acylglycerol acyl-chain remodeling; GO:0065008 regulation of biological quality; GO:0046486 glycerolipid metabolic process; GO:1901615 organic hydroxy compound metabolic process; GO:0010025 wax biosynthetic process; GO:0006066 alcohol metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0006639 acylglycerol metabolic process; GO:0001523 retinoid metabolic process; GO:0034308 primary alcohol metabolic process; GO:0009987 cellular process; GO:0006629 lipid metabolic process; GO:0006638 neutral lipid metabolic process; GO:0042445 hormone metabolic process; GO:0006720 isoprenoid metabolic process; GO:0010166 wax metabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0044238 primary metabolic process; GO:0034754 cellular hormone metabolic process; GO:0042572 retinol metabolic process; GO:0044710 single-organism metabolic process; GO:0010817 regulation of hormone levels; GO:0006721 terpenoid metabolic process; GO:0016101 diterpenoid metabolic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044432 endoplasmic reticulum part; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; ","GO:0016746 transferase activity, transferring acyl groups; GO:0050252 retinol O-fatty-acyltransferase activity; GO:0003824 catalytic activity; GO:0016411 acylglycerol O-acyltransferase activity; GO:0047196 long-chain-alcohol O-fatty-acyltransferase activity; GO:0003846 2-acylglycerol O-acyltransferase activity; GO:0103095 wax ester synthase activity; GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups; GO:0016740 transferase activity; GO:0008374 O-acyltransferase activity; ","K11156","DGAT2L4; diacylglycerol O-acyltransferase 2-like protein 4 [EC:2.3.1.75 2.3.1.76]","hsa04977 Vitamin digestion and absorption - Homo sapiens (human); hsa00830 Retinol metabolism - Homo sapiens (human); "]
["Q6EMK4","Vasorin OS=Homo sapiens OX=9606 GN=VASN","VASN",71.712,132.71,8,4,5,4,1.307,1.293,1.22,0.72,0.759,0.745,0.582,3.67e-05,"extracellular\r","GO:0050794 regulation of cellular process; GO:0051093 negative regulation of developmental process; GO:0033554 cellular response to stress; GO:0010717 regulation of epithelial to mesenchymal transition; GO:0009968 negative regulation of signal transduction; GO:0009628 response to abiotic stimulus; GO:0017015 regulation of transforming growth factor beta receptor signaling pathway; GO:0023051 regulation of signaling; GO:0051241 negative regulation of multicellular organismal process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:1903845 negative regulation of cellular response to transforming growth factor beta stimulus; GO:0050896 response to stimulus; GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0051239 regulation of multicellular organismal process; GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0010719 negative regulation of epithelial to mesenchymal transition; GO:0010646 regulation of cell communication; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0090288 negative regulation of cellular response to growth factor stimulus; GO:0001666 response to hypoxia; GO:0051775 response to redox state; GO:0070482 response to oxygen levels; GO:0045596 negative regulation of cell differentiation; GO:0071453 cellular response to oxygen levels; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:0070887 cellular response to chemical stimulus; GO:0045595 regulation of cell differentiation; GO:0071456 cellular response to hypoxia; GO:0051716 cellular response to stimulus; GO:0006950 response to stress; GO:0090287 regulation of cellular response to growth factor stimulus; GO:0048585 negative regulation of response to stimulus; GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway; GO:1903844 regulation of cellular response to transforming growth factor beta stimulus; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0048583 regulation of response to stimulus; GO:0036293 response to decreased oxygen levels; GO:0050793 regulation of developmental process; GO:0071461 cellular response to redox state; GO:0036294 cellular response to decreased oxygen levels; GO:2000026 regulation of multicellular organismal development; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0005765 lysosomal membrane; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0009986 cell surface; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0050839 cell adhesion molecule binding; GO:0019955 cytokine binding; GO:0005515 protein binding; GO:0019838 growth factor binding; GO:0050431 transforming growth factor beta binding; GO:0005488 binding; GO:0045296 cadherin binding; ",{"$nulls":3},"IPR013783; IPR000483; IPR000372; IPR032675; IPR003961; IPR000742; ","\"Immunoglobulin-like fold; Cysteine-rich flanking region, C-terminal; Leucine-rich repeat N-terminal domain; Leucine-rich repeat domain, L domain-like; Fibronectin type III; EGF-like domain; \"\r"]
["Q6IA69","Glutamine-dependent NAD(+) synthetase OS=Homo sapiens OX=9606 GN=NADSYN1","NADSYN1",79.284,7.1079,2.7,2,3,2,1.009,1.004,1.054,0.965,0.926,1.052,0.96,0.355,"nucleus\r","GO:0051188 cofactor biosynthetic process; GO:0009165 nucleotide biosynthetic process; GO:0019362 pyridine nucleotide metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0046496 nicotinamide nucleotide metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0019363 pyridine nucleotide biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:0072524 pyridine-containing compound metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0072525 pyridine-containing compound biosynthetic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0009108 coenzyme biosynthetic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0018130 heterocycle biosynthetic process; GO:0044711 single-organism biosynthetic process; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0044281 small molecule metabolic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0044763 single-organism cellular process; GO:1901293 nucleoside phosphate biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0019359 nicotinamide nucleotide biosynthetic process; GO:0006732 coenzyme metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0009435 NAD biosynthetic process; GO:0051186 cofactor metabolic process; GO:0090407 organophosphate biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0019674 NAD metabolic process; GO:0019637 organophosphate metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0044444 cytoplasmic part; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0016874 ligase activity; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor; GO:0016879 ligase activity, forming carbon-nitrogen bonds; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; GO:0004359 glutaminase activity; GO:0003952 NAD+ synthase (glutamine-hydrolyzing) activity; GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K01950","E6.3.5.1; NAD+ synthase (glutamine-hydrolysing) [EC:6.3.5.1]","hsa00760 Nicotinate and nicotinamide metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR003010; IPR014729; IPR022310; ","Carbon-nitrogen hydrolase; Rossmann-like alpha/beta/alpha sandwich fold; NAD/GMP synthase; \r"]
["Q6IA86","Elongator complex protein 2 OS=Homo sapiens OX=9606 GN=ELP2","ELP2",92.499,7.2208,4,2,2,2,1.007,1.1,0.967,0.994,0.955,0.992,0.957,0.346,"nucleus\r","GO:0046425 regulation of JAK-STAT cascade; GO:0050794 regulation of cellular process; GO:0006725 cellular aromatic compound metabolic process; GO:0097659 nucleic acid-templated transcription; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0023051 regulation of signaling; GO:0009058 biosynthetic process; GO:0006354 DNA-templated transcription, elongation; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0010646 regulation of cell communication; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0009966 regulation of signal transduction; GO:1904892 regulation of STAT cascade; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:1902531 regulation of intracellular signal transduction; GO:0006355 regulation of transcription, DNA-templated; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0006368 transcription elongation from RNA polymerase II promoter; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:0031323 regulation of cellular metabolic process; GO:1901576 organic substance biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0034645 cellular macromolecule biosynthetic process; GO:0090304 nucleic acid metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006351 transcription, DNA-templated; GO:0006366 transcription from RNA polymerase II promoter; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0010467 gene expression; GO:1901362 organic cyclic compound biosynthetic process; GO:0065007 biological regulation; GO:2000112 regulation of cellular macromolecule biosynthetic process; ","GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:1990234 transferase complex; GO:0005829 cytosol; GO:0005623 cell; GO:0000123 histone acetyltransferase complex; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0031248 protein acetyltransferase complex; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0008023 transcription elongation factor complex; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:1902493 acetyltransferase complex; GO:0033588 Elongator holoenzyme complex; GO:0044451 nucleoplasm part; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0019900 kinase binding; GO:0005488 binding; GO:0019899 enzyme binding; GO:0019901 protein kinase binding; ","K11374",null,null,"IPR017986; IPR015943; ","WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain; \r"]
["Q6ICL3","Transport and Golgi organization protein 2 homolog OS=Homo sapiens OX=9606 GN=TANGO2","TANGO2",30.937,2.127,2.9,1,1,1,1.163,0.989,0.937,0.933,0.963,1.028,0.947,0.508,"cytoplasm\r",null,"GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; "]
["Q6IQ22","Ras-related protein Rab-12 OS=Homo sapiens OX=9606 GN=RAB12","RAB12",27.248,14.254,20.9,6,10,6,1,0.968,0.957,0.99,1.115,0.935,1.039,0.538,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0044257 cellular protein catabolic process; GO:0031331 positive regulation of cellular catabolic process; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0006914 autophagy; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0071704 organic substance metabolic process; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0009896 positive regulation of catabolic process; GO:0044248 cellular catabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0009987 cellular process; GO:0007041 lysosomal transport; GO:0051716 cellular response to stimulus; GO:0044265 cellular macromolecule catabolic process; GO:0035556 intracellular signal transduction; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0048522 positive regulation of cellular process; GO:0071702 organic substance transport; GO:0007264 small GTPase mediated signal transduction; GO:0031323 regulation of cellular metabolic process; GO:0008333 endosome to lysosome transport; GO:0044238 primary metabolic process; GO:0023052 signaling; GO:0010506 regulation of autophagy; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0016241 regulation of macroautophagy; GO:0045184 establishment of protein localization; GO:0016197 endosomal transport; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0050789 regulation of biological process; GO:0010508 positive regulation of autophagy; GO:0007034 vacuolar transport; GO:0030163 protein catabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0061024 membrane organization; GO:0009057 macromolecule catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0016239 positive regulation of macroautophagy; GO:0019222 regulation of metabolic process; GO:0051179 localization; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0055038 recycling endosome membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005776 autophagosome; GO:0055037 recycling endosome; GO:0005765 lysosomal membrane; GO:0005622 intracellular; GO:0044464 cell part; GO:0005764 lysosome; GO:0098805 whole membrane; GO:0044431 Golgi apparatus part; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0010008 endosome membrane; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0005829 cytosol; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0019003 GDP binding; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; ","K07907",null,null,"IPR005225; IPR027417; ","Small GTP-binding protein domain; P-loop containing nucleoside triphosphate hydrolase; \r"]
["Q6NUK1","Calcium-binding mitochondrial carrier protein SCaMC-1 OS=Homo sapiens OX=9606 GN=SLC25A24","SLC25A24",53.354,26.181,20.5,9,14,9,1.014,1.016,0.989,0.987,1.02,0.979,0.989,0.508,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0010941 regulation of cell death; GO:0015867 ATP transport; GO:0006839 mitochondrial transport; GO:0044699 single-organism process; GO:0015868 purine ribonucleotide transport; GO:0050896 response to stimulus; GO:0051503 adenine nucleotide transport; GO:0051234 establishment of localization; GO:1902578 single-organism localization; GO:0015931 nucleobase-containing compound transport; GO:0006979 response to oxidative stress; GO:1901264 carbohydrate derivative transport; GO:0051592 response to calcium ion; GO:0034599 cellular response to oxidative stress; GO:0010035 response to inorganic substance; GO:0009987 cellular process; GO:0070887 cellular response to chemical stimulus; GO:0044765 single-organism transport; GO:0051716 cellular response to stimulus; GO:0006950 response to stress; GO:0015865 purine nucleotide transport; GO:0006862 nucleotide transport; GO:0071277 cellular response to calcium ion; GO:0071702 organic substance transport; GO:0010038 response to metal ion; GO:0015858 nucleoside transport; GO:0006820 anion transport; GO:0006810 transport; GO:0055085 transmembrane transport; GO:0015748 organophosphate ester transport; GO:0015711 organic anion transport; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0006811 ion transport; GO:0071241 cellular response to inorganic substance; GO:0051179 localization; GO:0071248 cellular response to metal ion; GO:0015866 ADP transport; GO:0071705 nitrogen compound transport; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044429 mitochondrial part; GO:0031090 organelle membrane; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0005740 mitochondrial envelope; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0031975 envelope; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0015216 purine nucleotide transmembrane transporter activity; GO:1901505 carbohydrate derivative transporter activity; GO:0015075 ion transmembrane transporter activity; GO:0043167 ion binding; GO:0022892 substrate-specific transporter activity; GO:0000295 adenine nucleotide transmembrane transporter activity; GO:0015932 nucleobase-containing compound transmembrane transporter activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0015217 ADP transmembrane transporter activity; GO:0015215 nucleotide transmembrane transporter activity; GO:0005488 binding; GO:0005346 purine ribonucleotide transmembrane transporter activity; GO:0015211 purine nucleoside transmembrane transporter activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005347 ATP transmembrane transporter activity; GO:0005337 nucleoside transmembrane transporter activity; GO:0005509 calcium ion binding; GO:0015605 organophosphate ester transmembrane transporter activity; GO:0008514 organic anion transmembrane transporter activity; GO:0008509 anion transmembrane transporter activity; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; ","K14684",null,null,"IPR023395; IPR011992; IPR002048; ","Mitochondrial carrier domain; EF-hand domain pair; EF-hand domain; \r"]
["Q6NUM9","All-trans-retinol 13,14-reductase OS=Homo sapiens OX=9606 GN=RETSAT","RETSAT",66.819,55.079,11.8,6,8,6,1.222,0.996,1.122,0.961,0.872,0.855,0.805,0.0364,"plasma membrane\r","GO:0006720 isoprenoid metabolic process; GO:0042445 hormone metabolic process; GO:0065008 regulation of biological quality; GO:1901615 organic hydroxy compound metabolic process; GO:0055114 oxidation-reduction process; GO:0006066 alcohol metabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0034754 cellular hormone metabolic process; GO:0008152 metabolic process; GO:0042572 retinol metabolic process; GO:0044710 single-organism metabolic process; GO:0001523 retinoid metabolic process; GO:0010817 regulation of hormone levels; GO:0016101 diterpenoid metabolic process; GO:0006721 terpenoid metabolic process; GO:0034308 primary alcohol metabolic process; GO:0009987 cellular process; GO:0006629 lipid metabolic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0019867 outer membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0098588 bounding membrane of organelle; GO:0031090 organelle membrane; GO:0005635 nuclear envelope; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005640 nuclear outer membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031965 nuclear membrane; GO:0005634 nucleus; GO:0044432 endoplasmic reticulum part; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0098805 whole membrane; GO:0031975 envelope; GO:0031968 organelle outer membrane; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors; GO:0051786 all-trans-retinol 13,14-reductase activity; GO:0003824 catalytic activity; GO:0016491 oxidoreductase activity; ","K09516","RETSAT; all-trans-retinol 13,14-reductase [EC:1.3.99.23]","hsa00830 Retinol metabolism - Homo sapiens (human); ","IPR023753; ","FAD/NAD(P)-binding domain; \r"]
["Q6NY19","KN motif and ankyrin repeat domain-containing protein 3 OS=Homo sapiens OX=9606 GN=KANK3","KANK3",88.424,12.4,4.4,3,3,3,1.002,1.151,1.232,0.846,0.98,0.808,0.778,0.0408,"nucleus\r",null,null,"GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR020683; ","Ankyrin repeat-containing domain; \r"]
["Q6NYC8","Phostensin OS=Homo sapiens OX=9606 GN=PPP1R18","PPP1R18",67.942,28.725,9.1,3,3,3,0.865,1.013,0.859,1.07,1.076,1.116,1.192,0.0324,"nucleus\r",null,"GO:0005856 cytoskeleton; GO:0043226 organelle; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0043228 non-membrane-bounded organelle; ","GO:0003779 actin binding; GO:0005515 protein binding; GO:0019902 phosphatase binding; GO:0008092 cytoskeletal protein binding; GO:0019899 enzyme binding; GO:0005488 binding; ","K17559",null,null,"IPR025907; IPR025903; ","Phostensin/Taperin PP1-binding domain; Phostensin/Taperin N-terminal domain; \r"]
["Q6P179","Endoplasmic reticulum aminopeptidase 2 OS=Homo sapiens OX=9606 GN=ERAP2","ERAP2",110.46,16.935,3.6,3,3,3,0.442,0.543,0.686,1.452,1.444,1.38,2.559,0.0175,"mitochondria\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0008217 regulation of blood pressure; GO:0065008 regulation of biological quality; GO:0006518 peptide metabolic process; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0019883 antigen processing and presentation of endogenous antigen; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I; GO:0043171 peptide catabolic process; GO:0002250 adaptive immune response; GO:0008015 blood circulation; GO:0044248 cellular catabolic process; GO:0006508 proteolysis; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009987 cellular process; GO:0051716 cellular response to stimulus; GO:0003008 system process; GO:0048002 antigen processing and presentation of peptide antigen; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:0002376 immune system process; GO:0043603 cellular amide metabolic process; GO:0044238 primary metabolic process; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0019882 antigen processing and presentation; GO:1901575 organic substance catabolic process; GO:0050789 regulation of biological process; GO:1901565 organonitrogen compound catabolic process; GO:0007267 cell-cell signaling; GO:0002483 antigen processing and presentation of endogenous peptide antigen; GO:0006955 immune response; GO:0003013 circulatory system process; GO:0009056 catabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0005788 endoplasmic reticulum lumen; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044432 endoplasmic reticulum part; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0008238 exopeptidase activity; GO:0008233 peptidase activity; GO:0043167 ion binding; GO:0070006 metalloaminopeptidase activity; GO:0008235 metalloexopeptidase activity; GO:0004177 aminopeptidase activity; GO:0016787 hydrolase activity; GO:0008237 metallopeptidase activity; GO:0033218 amide binding; GO:0008270 zinc ion binding; GO:0004175 endopeptidase activity; GO:0046914 transition metal ion binding; GO:0042277 peptide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0046872 metal ion binding; GO:0043169 cation binding; ","K13723",null,null,"IPR014782; IPR024571; ","\"Peptidase M1, membrane alanine aminopeptidase, N-terminal; ERAP1-like C-terminal domain; \"\r"]
["Q6P1M0","Long-chain fatty acid transport protein 4 OS=Homo sapiens OX=9606 GN=SLC27A4","SLC27A4",72.063,15.666,7.6,5,6,5,0.806,0.829,0.784,1.169,1.171,1.208,1.467,3.91e-05,"extracellular\r","GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0015718 monocarboxylic acid transport; GO:0032787 monocarboxylic acid metabolic process; GO:0033036 macromolecule localization; GO:0006629 lipid metabolic process; GO:0044765 single-organism transport; GO:0032502 developmental process; GO:0043588 skin development; GO:0006869 lipid transport; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0072329 monocarboxylic acid catabolic process; GO:0046942 carboxylic acid transport; GO:0032501 multicellular organismal process; GO:0046395 carboxylic acid catabolic process; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0048513 animal organ development; GO:0042221 response to chemical; GO:0044710 single-organism metabolic process; GO:0006082 organic acid metabolic process; GO:0009062 fatty acid catabolic process; GO:0048856 anatomical structure development; GO:0043436 oxoacid metabolic process; GO:0044707 single-multicellular organism process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0009991 response to extracellular stimulus; GO:0015908 fatty acid transport; GO:1902578 single-organism localization; GO:0044248 cellular catabolic process; GO:0007275 multicellular organism development; GO:0042760 very long-chain fatty acid catabolic process; GO:0009987 cellular process; GO:0016042 lipid catabolic process; GO:0048731 system development; GO:0044712 single-organism catabolic process; GO:0071702 organic substance transport; GO:0010876 lipid localization; GO:0044282 small molecule catabolic process; GO:0006631 fatty acid metabolic process; GO:0044238 primary metabolic process; GO:0007584 response to nutrient; GO:0015849 organic acid transport; GO:0044539 long-chain fatty acid import; GO:0015909 long-chain fatty acid transport; GO:0006820 anion transport; GO:0000038 very long-chain fatty acid metabolic process; GO:0015711 organic anion transport; GO:0001579 medium-chain fatty acid transport; GO:0044767 single-organism developmental process; GO:0006811 ion transport; GO:0001676 long-chain fatty acid metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0016054 organic acid catabolic process; GO:0044242 cellular lipid catabolic process; GO:0031667 response to nutrient levels; GO:0051179 localization; GO:0009056 catabolic process; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0042995 cell projection; GO:0098862 cluster of actin-based cell projections; GO:0005783 endoplasmic reticulum; GO:0005903 brush border; GO:0031526 brush border membrane; GO:0071944 cell periphery; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0098858 actin-based cell projection; GO:0044463 cell projection part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0098590 plasma membrane region; GO:0044459 plasma membrane part; GO:0044432 endoplasmic reticulum part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005902 microvillus; GO:0031253 cell projection membrane; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0004467 long-chain fatty acid-CoA ligase activity; GO:0016874 ligase activity; GO:0005319 lipid transporter activity; GO:0022892 substrate-specific transporter activity; GO:0016877 ligase activity, forming carbon-sulfur bonds; GO:0000166 nucleotide binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0015245 fatty acid transporter activity; GO:0015645 fatty acid ligase activity; GO:0031957 very long-chain fatty acid-CoA ligase activity; GO:0036094 small molecule binding; GO:0005215 transporter activity; ","K08745","SLC27A1_4; solute carrier family 27 (fatty acid transporter), member 1/4 [EC:6.2.1.-]","hsa04975 Fat digestion and absorption - Homo sapiens (human); hsa03320 PPAR signaling pathway - Homo sapiens (human); hsa04931 Insulin resistance - Homo sapiens (human); ","IPR025110; IPR000873; ","AMP-binding enzyme C-terminal domain; AMP-dependent synthetase/ligase; \r"]
["Q6P2E9","Enhancer of mRNA-decapping protein 4 OS=Homo sapiens OX=9606 GN=EDC4","EDC4",151.66,16.445,5.5,7,8,7,0.971,0.93,0.971,1.033,1.068,1.029,1.09,0.00984,"nucleus\r","GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0048519 negative regulation of biological process; GO:0044237 cellular metabolic process; GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0008152 metabolic process; GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901361 organic cyclic compound catabolic process; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0043170 macromolecule metabolic process; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0010468 regulation of gene expression; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic; GO:0044238 primary metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0009892 negative regulation of metabolic process; GO:0006401 RNA catabolic process; GO:0016070 RNA metabolic process; GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; GO:0019439 aromatic compound catabolic process; GO:1901575 organic substance catabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; GO:0009057 macromolecule catabolic process; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0090305 nucleic acid phosphodiester bond hydrolysis; GO:0009056 catabolic process; GO:0016071 mRNA metabolic process; GO:0065007 biological regulation; GO:0046700 heterocycle catabolic process; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0043232 intracellular non-membrane-bounded organelle; GO:0000932 P-body; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0035770 ribonucleoprotein granule; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0005488 binding; ","K12616","EDC4; enhancer of mRNA-decapping protein 4","hsa03018 RNA degradation - Homo sapiens (human); ","IPR017986; IPR015943; IPR032401; ","\"WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain; Enhancer of mRNA-decapping protein 4, WD40 repeat region; \"\r"]
["Q6P4A8","Phospholipase B-like 1 OS=Homo sapiens OX=9606 GN=PLBD1","PLBD1",63.254,20.046,12.3,7,7,7,0.829,0.793,0.812,1.211,1.159,1.191,1.463,3.52e-05,"extracellular\r","GO:0046470 phosphatidylcholine metabolic process; GO:0016042 lipid catabolic process; GO:0046486 glycerolipid metabolic process; GO:0044712 single-organism catabolic process; GO:0036152 phosphatidylethanolamine acyl-chain remodeling; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:0097164 ammonium ion metabolic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0036151 phosphatidylcholine acyl-chain remodeling; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:1901575 organic substance catabolic process; GO:0008152 metabolic process; GO:0036149 phosphatidylinositol acyl-chain remodeling; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0019637 organophosphate metabolic process; GO:0006650 glycerophospholipid metabolic process; GO:0046488 phosphatidylinositol metabolic process; GO:0006644 phospholipid metabolic process; GO:0009987 cellular process; GO:0009056 catabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0006629 lipid metabolic process; ","GO:0043229 intracellular organelle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005622 intracellular; GO:0044464 cell part; GO:0005764 lysosome; GO:0005773 vacuole; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0000323 lytic vacuole; ","GO:0052689 carboxylic ester hydrolase activity; GO:0003824 catalytic activity; GO:0004623 phospholipase A2 activity; GO:0016788 hydrolase activity, acting on ester bonds; GO:0004622 lysophospholipase activity; GO:0004620 phospholipase activity; GO:0016787 hydrolase activity; GO:0016298 lipase activity; "]
["Q6P597","Kinesin light chain 3 OS=Homo sapiens OX=9606 GN=KLC3","KLC3",55.364,17.306,13.7,6,6,4,0.904,0.85,0.872,1.106,1.158,1.097,1.28,0.000555,"cytoplasm\r","GO:0046907 intracellular transport; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0007017 microtubule-based process; GO:1902582 single-organism intracellular transport; GO:0099111 microtubule-based transport; GO:0030705 cytoskeleton-dependent intracellular transport; GO:0051641 cellular localization; GO:0051234 establishment of localization; GO:0006810 transport; GO:0007018 microtubule-based movement; GO:0008088 axo-dendritic transport; GO:0010970 transport along microtubule; GO:0051649 establishment of localization in cell; GO:1902578 single-organism localization; GO:0006928 movement of cell or subcellular component; GO:1902580 single-organism cellular localization; GO:0051179 localization; GO:0009987 cellular process; GO:0044765 single-organism transport; ","GO:0005929 cilium; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0099513 polymeric cytoskeletal fiber; GO:0005874 microtubule; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0005875 microtubule associated complex; GO:0044463 cell projection part; GO:0031514 motile cilium; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0099081 supramolecular polymer; GO:0005871 kinesin complex; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0005856 cytoskeleton; GO:0044441 ciliary part; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0043005 neuron projection; GO:0043234 protein complex; GO:0097458 neuron part; GO:0035253 ciliary rootlet; ","GO:0016462 pyrophosphatase activity; GO:0003774 motor activity; GO:0008092 cytoskeletal protein binding; GO:0003824 catalytic activity; GO:0019894 kinesin binding; GO:0008017 microtubule binding; GO:0005488 binding; GO:0015631 tubulin binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0017111 nucleoside-triphosphatase activity; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0003777 microtubule motor activity; ","K10407","KLC; kinesin light chain","hsa05132 Salmonella infection - Homo sapiens (human); ","IPR011990; IPR013026; ","Tetratricopeptide-like helical domain; Tetratricopeptide repeat-containing domain; \r"]
["Q6P996","Pyridoxal-dependent decarboxylase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PDXDC1","PDXDC1",86.706,8.4188,4.4,3,3,3,1.026,0.765,1.16,1.06,0.987,1.002,1.033,0.727,"cytoplasm\r","GO:0008152 metabolic process; GO:0044710 single-organism metabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0019752 carboxylic acid metabolic process; GO:0044699 single-organism process; GO:0006082 organic acid metabolic process; GO:0044237 cellular metabolic process; GO:0009987 cellular process; GO:0043436 oxoacid metabolic process; GO:0071704 organic substance metabolic process; ","GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0043229 intracellular organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005794 Golgi apparatus; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0050839 cell adhesion molecule binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016830 carbon-carbon lyase activity; GO:0045296 cadherin binding; GO:0043167 ion binding; GO:0016831 carboxy-lyase activity; GO:0016829 lyase activity; GO:0005515 protein binding; GO:0043168 anion binding; GO:0048037 cofactor binding; GO:0030170 pyridoxal phosphate binding; ",{"$nulls":3},"IPR015424; IPR015421; IPR015422; ","\"Pyridoxal phosphate-dependent transferase; Pyridoxal phosphate-dependent transferase, major region, subdomain 1; Pyridoxal phosphate-dependent transferase, major region, subdomain 2; \"\r"]
["Q6PI48","Aspartate--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=DARS2","DARS2",73.562,3.8344,4,3,3,3,0.996,0.842,1.087,1.15,0.915,1.015,1.053,0.625,"mitochondria\r","GO:0006518 peptide metabolic process; GO:0070127 tRNA aminoacylation for mitochondrial protein translation; GO:0006725 cellular aromatic compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0006421 asparaginyl-tRNA aminoacylation; GO:0009058 biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0043039 tRNA aminoacylation; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0070145 mitochondrial asparaginyl-tRNA aminoacylation; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0006418 tRNA aminoacylation for protein translation; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0006412 translation; GO:0009987 cellular process; GO:0000959 mitochondrial RNA metabolic process; GO:0043043 peptide biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0032543 mitochondrial translation; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0016070 RNA metabolic process; GO:0006399 tRNA metabolic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0090304 nucleic acid metabolic process; GO:0044710 single-organism metabolic process; GO:0043038 amino acid activation; GO:0019752 carboxylic acid metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0006082 organic acid metabolic process; GO:0034660 ncRNA metabolic process; GO:0043436 oxoacid metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds; GO:1901265 nucleoside phosphate binding; GO:0016875 ligase activity, forming carbon-oxygen bonds; GO:0046983 protein dimerization activity; GO:0016874 ligase activity; GO:0005515 protein binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0042802 identical protein binding; GO:0000049 tRNA binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0004812 aminoacyl-tRNA ligase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003723 RNA binding; GO:0005524 ATP binding; GO:0050560 aspartate-tRNA(Asn) ligase activity; GO:0004815 aspartate-tRNA ligase activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0042803 protein homodimerization activity; GO:0003676 nucleic acid binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; ","K01876","aspS; aspartyl-tRNA synthetase [EC:6.1.1.12]","hsa00970 Aminoacyl-tRNA biosynthesis - Homo sapiens (human); ","IPR004364; IPR012340; IPR004365; IPR029351; IPR004115; IPR006195; ","\"Aminoacyl-tRNA synthetase, class II (D/K/N); Nucleic acid-binding, OB-fold; OB-fold nucleic acid binding domain, AA-tRNA synthetase-type; GAD domain; GAD-like domain; Aminoacyl-tRNA synthetase, class II; \"\r"]
["Q6PI78","Transmembrane protein 65 OS=Homo sapiens OX=9606 GN=TMEM65","TMEM65",25.498,3.4366,4.2,1,1,1,1.031,1.074,1.119,0.935,0.853,1.005,0.866,0.052,"plasma membrane\r","GO:0032502 developmental process; GO:0072359 circulatory system development; GO:0044707 single-multicellular organism process; GO:0048731 system development; GO:1903522 regulation of blood circulation; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0008016 regulation of heart contraction; GO:0032501 multicellular organismal process; GO:0051239 regulation of multicellular organismal process; GO:0003205 cardiac chamber development; GO:1903779 regulation of cardiac conduction; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0007507 heart development; GO:0044767 single-organism developmental process; GO:0044057 regulation of system process; GO:0007275 multicellular organism development; GO:0048856 anatomical structure development; GO:0003231 cardiac ventricle development; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0044291 cell-cell contact zone; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0005911 cell-cell junction; GO:0016021 integral component of membrane; GO:0005739 mitochondrion; GO:0014704 intercalated disc; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; "]
["Q6PKG0","La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1","LARP1",123.51,7.491,3.6,4,4,4,0.709,1.19,0.627,1.368,0.906,1.208,1.378,0.208,"nucleus\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0006518 peptide metabolic process; GO:0032270 positive regulation of cellular protein metabolic process; GO:0043489 RNA stabilization; GO:0010608 posttranscriptional regulation of gene expression; GO:0009891 positive regulation of biosynthetic process; GO:0044237 cellular metabolic process; GO:0009605 response to external stimulus; GO:0031929 TOR signaling; GO:0008152 metabolic process; GO:0009719 response to endogenous stimulus; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0034249 negative regulation of cellular amide metabolic process; GO:0097306 cellular response to alcohol; GO:0031323 regulation of cellular metabolic process; GO:0010506 regulation of autophagy; GO:0016241 regulation of macroautophagy; GO:0010243 response to organonitrogen compound; GO:0010508 positive regulation of autophagy; GO:0032269 negative regulation of cellular protein metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:1901698 response to nitrogen compound; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0016239 positive regulation of macroautophagy; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0048255 mRNA stabilization; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:1990928 response to amino acid starvation; GO:0044267 cellular protein metabolic process; GO:1901700 response to oxygen-containing compound; GO:0017148 negative regulation of translation; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0071362 cellular response to ether; GO:0043487 regulation of RNA stability; GO:0045472 response to ether; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0009896 positive regulation of catabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:1901655 cellular response to ketone; GO:0006950 response to stress; GO:0043900 regulation of multi-organism process; GO:0071407 cellular response to organic cyclic compound; GO:0097305 response to alcohol; GO:0008283 cell proliferation; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0034248 regulation of cellular amide metabolic process; GO:0009890 negative regulation of biosynthetic process; GO:0051247 positive regulation of protein metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:1901564 organonitrogen compound metabolic process; GO:0031331 positive regulation of cellular catabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0072752 cellular response to rapamycin; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0006413 translational initiation; GO:0006412 translation; GO:0070887 cellular response to chemical stimulus; GO:0010468 regulation of gene expression; GO:1903902 positive regulation of viral life cycle; GO:0043902 positive regulation of multi-organism process; GO:0031326 regulation of cellular biosynthetic process; GO:0045727 positive regulation of translation; GO:0043043 peptide biosynthetic process; GO:0048522 positive regulation of cellular process; GO:0043603 cellular amide metabolic process; GO:0045069 regulation of viral genome replication; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0071417 cellular response to organonitrogen compound; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0042221 response to chemical; GO:1901699 cellular response to nitrogen compound; GO:0019222 regulation of metabolic process; GO:0038202 TORC1 signaling; GO:1901355 response to rapamycin; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0009991 response to extracellular stimulus; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0045070 positive regulation of viral genome replication; GO:0009987 cellular process; GO:0010629 negative regulation of gene expression; GO:0035556 intracellular signal transduction; GO:0050792 regulation of viral process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0043488 regulation of mRNA stability; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:1901701 cellular response to oxygen-containing compound; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0048524 positive regulation of viral process; GO:0006417 regulation of translation; GO:0051246 regulation of protein metabolic process; GO:0071495 cellular response to endogenous stimulus; GO:0051248 negative regulation of protein metabolic process; GO:0034250 positive regulation of cellular amide metabolic process; GO:0042594 response to starvation; GO:0010467 gene expression; GO:0031327 negative regulation of cellular biosynthetic process; GO:0031667 response to nutrient levels; GO:0043604 amide biosynthetic process; GO:1903900 regulation of viral life cycle; GO:0065007 biological regulation; GO:1901654 response to ketone; ","GO:0010494 cytoplasmic stress granule; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0035770 ribonucleoprotein granule; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0044444 cytoplasmic part; ","GO:0003723 RNA binding; GO:0000339 RNA cap binding; GO:0048027 mRNA 5'-UTR binding; GO:0090079 translation regulator activity, nucleic acid binding; GO:0003730 mRNA 3'-UTR binding; GO:0005515 protein binding; GO:0045182 translation regulator activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0003729 mRNA binding; GO:0050839 cell adhesion molecule binding; GO:0005488 binding; GO:0031369 translation initiation factor binding; GO:0003676 nucleic acid binding; GO:0045296 cadherin binding; GO:0008190 eukaryotic initiation factor 4E binding; GO:0008494 translation activator activity; ","K18757",null,null,"IPR006630; IPR011991; ","RNA-binding protein Lupus La; Winged helix-turn-helix DNA-binding domain; \r"]
["Q6STE5","SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 OS=Homo sapiens OX=9606 GN=SMARCD3","SMARCD3",55.015,1.8984,2.5,1,1,1,0.927,0.956,0.85,1.104,1.143,1.02,1.195,0.0215,"nucleus\r","GO:0097659 nucleic acid-templated transcription; GO:0003211 cardiac ventricle formation; GO:0009891 positive regulation of biosynthetic process; GO:2000648 positive regulation of stem cell proliferation; GO:0003407 neural retina development; GO:0044255 cellular lipid metabolic process; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0007507 heart development; GO:0051240 positive regulation of multicellular organismal process; GO:0003208 cardiac ventricle morphogenesis; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0043170 macromolecule metabolic process; GO:0090068 positive regulation of cell cycle process; GO:0051147 regulation of muscle cell differentiation; GO:0007399 nervous system development; GO:0018130 heterocycle biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0031498 chromatin disassembly; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044763 single-organism cellular process; GO:0032774 RNA biosynthetic process; GO:1902751 positive regulation of cell cycle G2/M phase transition; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0045931 positive regulation of mitotic cell cycle; GO:0044710 single-organism metabolic process; GO:0006337 nucleosome disassembly; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:2000179 positive regulation of neural precursor cell proliferation; GO:0010604 positive regulation of macromolecule metabolic process; GO:0009887 animal organ morphogenesis; GO:0051149 positive regulation of muscle cell differentiation; GO:0051094 positive regulation of developmental process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0072359 circulatory system development; GO:1902692 regulation of neuroblast proliferation; GO:0050794 regulation of cellular process; GO:0034728 nucleosome organization; GO:0044707 single-multicellular organism process; GO:0007346 regulation of mitotic cell cycle; GO:0006338 chromatin remodeling; GO:0072091 regulation of stem cell proliferation; GO:0042127 regulation of cell proliferation; GO:0007389 pattern specification process; GO:1901989 positive regulation of cell cycle phase transition; GO:0003215 cardiac right ventricle morphogenesis; GO:0051239 regulation of multicellular organismal process; GO:0002052 positive regulation of neuroblast proliferation; GO:0045597 positive regulation of cell differentiation; GO:0009653 anatomical structure morphogenesis; GO:0001654 eye development; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:1901987 regulation of cell cycle phase transition; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0051152 positive regulation of smooth muscle cell differentiation; GO:0061061 muscle structure development; GO:0051171 regulation of nitrogen compound metabolic process; GO:0010389 regulation of G2/M transition of mitotic cell cycle; GO:1902680 positive regulation of RNA biosynthetic process; GO:0016569 covalent chromatin modification; GO:0007275 multicellular organism development; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0003231 cardiac ventricle development; GO:0045787 positive regulation of cell cycle; GO:0051254 positive regulation of RNA metabolic process; GO:0048731 system development; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0032984 macromolecular complex disassembly; GO:0003206 cardiac chamber morphogenesis; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0051276 chromosome organization; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0050769 positive regulation of neurogenesis; GO:0031328 positive regulation of cellular biosynthetic process; GO:0043412 macromolecule modification; GO:0007423 sensory organ development; GO:0050793 regulation of developmental process; GO:0008284 positive regulation of cell proliferation; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0009058 biosynthetic process; GO:2001141 regulation of RNA biosynthetic process; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0003207 cardiac chamber formation; GO:0010720 positive regulation of cell development; GO:0051726 regulation of cell cycle; GO:0071824 protein-DNA complex subunit organization; GO:0006629 lipid metabolic process; GO:0032502 developmental process; GO:0003219 cardiac right ventricle formation; GO:0006333 chromatin assembly or disassembly; GO:0010468 regulation of gene expression; GO:0003128 heart field specification; GO:0031326 regulation of cellular biosynthetic process; GO:0003007 heart morphogenesis; GO:0051962 positive regulation of nervous system development; GO:0051098 regulation of binding; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0048645 animal organ formation; GO:0003139 secondary heart field specification; GO:0016070 RNA metabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0060914 heart formation; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0006325 chromatin organization; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0016043 cellular component organization; GO:0043010 camera-type eye development; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0043393 regulation of protein binding; GO:0030154 cell differentiation; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0032986 protein-DNA complex disassembly; GO:0045595 regulation of cell differentiation; GO:0060041 retina development in camera-type eye; GO:0006355 regulation of transcription, DNA-templated; GO:0003002 regionalization; GO:0051150 regulation of smooth muscle cell differentiation; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:1902749 regulation of cell cycle G2/M phase transition; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0010092 specification of animal organ identity; GO:0043933 macromolecular complex subunit organization; GO:0003205 cardiac chamber development; GO:2000177 regulation of neural precursor cell proliferation; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0044767 single-organism developmental process; GO:0042692 muscle cell differentiation; GO:0022411 cellular component disassembly; GO:0010467 gene expression; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0010971 positive regulation of G2/M transition of mitotic cell cycle; GO:1901992 positive regulation of mitotic cell cycle phase transition; GO:0050767 regulation of neurogenesis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0070603 SWI/SNF superfamily-type complex; GO:0005623 cell; GO:0044422 organelle part; GO:0071565 nBAF complex; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044454 nuclear chromosome part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0000790 nuclear chromatin; GO:0071564 npBAF complex; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0000785 chromatin; GO:0000228 nuclear chromosome; GO:0043234 protein complex; GO:0090544 BAF-type complex; GO:0016514 SWI/SNF complex; GO:0044428 nuclear part; ","GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity; GO:0005102 receptor binding; GO:0005488 binding; GO:0016922 ligand-dependent nuclear receptor binding; GO:0035257 nuclear hormone receptor binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0005515 protein binding; GO:0003713 transcription coactivator activity; GO:0051427 hormone receptor binding; GO:0003682 chromatin binding; GO:0003712 transcription cofactor activity; GO:0000988 transcription factor activity, protein binding; GO:0008134 transcription factor binding; ","K11650","SMARCD; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D","hsa05225 Hepatocellular carcinoma - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); ","IPR003121; IPR019835; ","SWIB/MDM2 domain; SWIB domain; \r"]
["Q6UW02","Cytochrome P450 20A1 OS=Homo sapiens OX=9606 GN=CYP20A1","CYP20A1",52.432,12.999,14.1,6,6,6,1.065,1.108,0.865,1.013,0.916,1.049,0.98,0.864,"endoplasmic reticulum\r","GO:0044699 single-organism process; GO:0008152 metabolic process; GO:0055114 oxidation-reduction process; GO:0044710 single-organism metabolic process; ","GO:0031224 intrinsic component of membrane; GO:0016020 membrane; GO:0016021 integral component of membrane; GO:0044425 membrane part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0020037 heme binding; GO:0005506 iron ion binding; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0004497 monooxygenase activity; GO:0046906 tetrapyrrole binding; GO:0016491 oxidoreductase activity; ","K07435"]
["Q6UWN5","Ly6/PLAUR domain-containing protein 5 OS=Homo sapiens OX=9606 GN=LYPD5","LYPD5",26.936,24.773,6.4,1,1,1,0.67,0.912,0.489,1.222,1.236,1.445,1.885,0.0243,"extracellular\r","GO:0043687 post-translational protein modification; GO:0006501 C-terminal protein lipidation; GO:0044267 cellular protein metabolic process; GO:0009058 biosynthetic process; GO:0044238 primary metabolic process; GO:0018410 C-terminal protein amino acid modification; GO:0044237 cellular metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0042157 lipoprotein metabolic process; GO:0071704 organic substance metabolic process; GO:0022610 biological adhesion; GO:0008152 metabolic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0031589 cell-substrate adhesion; GO:0007160 cell-matrix adhesion; GO:0044260 cellular macromolecule metabolic process; GO:0007155 cell adhesion; GO:0006497 protein lipidation; GO:0006464 cellular protein modification process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:0009987 cellular process; GO:0042158 lipoprotein biosynthetic process; ","GO:0016020 membrane; GO:0044464 cell part; GO:0071944 cell periphery; GO:0044425 membrane part; GO:0031225 anchored component of membrane; GO:0031224 intrinsic component of membrane; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; ","GO:0005515 protein binding; GO:0043236 laminin binding; GO:0005488 binding; GO:0050840 extracellular matrix binding; ",{"$nulls":3},"IPR016054; ","Ly-6 antigen/uPA receptor-like; \r"]
["Q6UWY5","Olfactomedin-like protein 1 OS=Homo sapiens OX=9606 GN=OLFML1","OLFML1",45.95,78.385,30.6,12,15,12,1.093,1.086,1.083,0.887,0.917,0.939,0.841,0.000485,"endoplasmic reticulum\r",null,"GO:0005576 extracellular region; ",{"$nulls":4},"IPR003112; ","Olfactomedin-like domain; \r"]
["Q6UXH1","Cysteine-rich with EGF-like domain protein 2 OS=Homo sapiens OX=9606 GN=CRELD2","CRELD2",38.191,6.6935,4.5,1,1,1,1.053,0.954,1.064,1.043,0.989,0.909,0.958,0.457,"extracellular\r",null,"GO:0043229 intracellular organelle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0005737 cytoplasm; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0005509 calcium ion binding; GO:0005488 binding; GO:0043167 ion binding; ",{"$nulls":3},"IPR001881; IPR002049; IPR000742; IPR009030; ","EGF-like calcium-binding domain; Laminin EGF domain; EGF-like domain; Growth factor receptor cysteine-rich domain; \r"]
["Q6UY14","ADAMTS-like protein 4 OS=Homo sapiens OX=9606 GN=ADAMTSL4","ADAMTSL4",116.54,14.951,3.2,3,3,3,1.191,1.024,1.032,0.897,0.997,0.877,0.853,0.0667,"extracellular\r","GO:0050794 regulation of cellular process; GO:0043413 macromolecule glycosylation; GO:0016043 cellular component organization; GO:0010941 regulation of cell death; GO:0036065 fucosylation; GO:0048869 cellular developmental process; GO:0044267 cellular protein metabolic process; GO:0043067 regulation of programmed cell death; GO:0043065 positive regulation of apoptotic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0048468 cell development; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0030154 cell differentiation; GO:1901137 carbohydrate derivative biosynthetic process; GO:0043062 extracellular structure organization; GO:0006915 apoptotic process; GO:1901135 carbohydrate derivative metabolic process; GO:0006508 proteolysis; GO:0030198 extracellular matrix organization; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0070085 glycosylation; GO:0032502 developmental process; GO:0006486 protein glycosylation; GO:0060429 epithelium development; GO:0009101 glycoprotein biosynthetic process; GO:0002064 epithelial cell development; GO:0009888 tissue development; GO:0044763 single-organism cellular process; GO:0009100 glycoprotein metabolic process; GO:0048522 positive regulation of cellular process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0010942 positive regulation of cell death; GO:0050789 regulation of biological process; GO:0034645 cellular macromolecule biosynthetic process; GO:0008219 cell death; GO:0044710 single-organism metabolic process; GO:0044767 single-organism developmental process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0006493 protein O-linked glycosylation; GO:0012501 programmed cell death; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:0036066 protein O-linked fucosylation; GO:0048856 anatomical structure development; GO:0043068 positive regulation of programmed cell death; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0030855 epithelial cell differentiation; GO:0065007 biological regulation; ","GO:0005788 endoplasmic reticulum lumen; GO:0043229 intracellular organelle; GO:0005615 extracellular space; GO:0005783 endoplasmic reticulum; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0005614 interstitial matrix; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0031012 extracellular matrix; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044432 endoplasmic reticulum part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005578 proteinaceous extracellular matrix; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0004175 endopeptidase activity; GO:0002020 protease binding; GO:0004222 metalloendopeptidase activity; GO:0008233 peptidase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0008237 metallopeptidase activity; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0019899 enzyme binding; ",{"$nulls":3},"IPR010294; IPR010909; ","ADAM-TS Spacer 1; PLAC; \r"]
["Q6VY07","Phosphofurin acidic cluster sorting protein 1 OS=Homo sapiens OX=9606 GN=PACS1","PACS1",104.9,14.175,3.6,3,3,3,0.937,1.174,1.076,0.916,0.99,0.923,0.888,0.175,"nucleus\r","GO:0010256 endomembrane system organization; GO:0072594 establishment of protein localization to organelle; GO:0044699 single-organism process; GO:0090002 establishment of protein localization to plasma membrane; GO:0044764 multi-organism cellular process; GO:0031347 regulation of defense response; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0051649 establishment of localization in cell; GO:0050690 regulation of defense response to virus by virus; GO:0033365 protein localization to organelle; GO:0044419 interspecies interaction between organisms; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0002697 regulation of immune effector process; GO:0044765 single-organism transport; GO:0072657 protein localization to membrane; GO:0006891 intra-Golgi vesicle-mediated transport; GO:0000301 retrograde transport, vesicle recycling within Golgi; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0007009 plasma membrane organization; GO:0051704 multi-organism process; GO:1902582 single-organism intracellular transport; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0048583 regulation of response to stimulus; GO:0002682 regulation of immune system process; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0072661 protein targeting to plasma membrane; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0002831 regulation of response to biotic stimulus; GO:0048193 Golgi vesicle transport; GO:0080134 regulation of response to stress; GO:1990778 protein localization to cell periphery; GO:0050688 regulation of defense response to virus; GO:1902578 single-organism localization; GO:0016032 viral process; GO:0006886 intracellular protein transport; GO:1902580 single-organism cellular localization; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0090150 establishment of protein localization to membrane; GO:0034067 protein localization to Golgi apparatus; GO:0043900 regulation of multi-organism process; GO:0072600 establishment of protein localization to Golgi; GO:0016192 vesicle-mediated transport; GO:0050792 regulation of viral process; GO:0044802 single-organism membrane organization; GO:0071702 organic substance transport; GO:0032101 regulation of response to external stimulus; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0072659 protein localization to plasma membrane; GO:0070727 cellular macromolecule localization; GO:0061024 membrane organization; GO:0051179 localization; GO:0000042 protein targeting to Golgi; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0031410 cytoplasmic vesicle; GO:0030137 COPI-coated vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005798 Golgi-associated vesicle; GO:0030135 coated vesicle; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005622 intracellular; GO:0044464 cell part; GO:0044431 Golgi apparatus part; GO:0043227 membrane-bounded organelle; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:0044325 ion channel binding; GO:0005515 protein binding; GO:0005488 binding; "]
["Q6XQN6","Nicotinate phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=NAPRT","NAPRT",57.578,67.029,19.7,9,12,9,1.008,1.026,1.007,0.939,1.028,1.02,0.982,0.562,"nucleus\r","GO:0051188 cofactor biosynthetic process; GO:0045321 leukocyte activation; GO:0019362 pyridine nucleotide metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0019363 pyridine nucleotide biosynthetic process; GO:0044237 cellular metabolic process; GO:0072524 pyridine-containing compound metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0072525 pyridine-containing compound biosynthetic process; GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway; GO:0008152 metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0006979 response to oxidative stress; GO:0009108 coenzyme biosynthetic process; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0002443 leukocyte mediated immunity; GO:0019357 nicotinate nucleotide biosynthetic process; GO:0018130 heterocycle biosynthetic process; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0002446 neutrophil mediated immunity; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0006732 coenzyme metabolic process; GO:0019359 nicotinamide nucleotide biosynthetic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0051186 cofactor metabolic process; GO:0006810 transport; GO:0090407 organophosphate biosynthetic process; GO:0032940 secretion by cell; GO:0043094 cellular metabolic compound salvage; GO:0044710 single-organism metabolic process; GO:0019674 NAD metabolic process; GO:0043299 leukocyte degranulation; GO:1901362 organic cyclic compound biosynthetic process; GO:0043173 nucleotide salvage; GO:0009165 nucleotide biosynthetic process; GO:0002283 neutrophil activation involved in immune response; GO:0006725 cellular aromatic compound metabolic process; GO:0046496 nicotinamide nucleotide metabolic process; GO:0002252 immune effector process; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0002275 myeloid cell activation involved in immune response; GO:0046483 heterocycle metabolic process; GO:1902578 single-organism localization; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0036230 granulocyte activation; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0019358 nicotinate nucleotide salvage; GO:0044711 single-organism biosynthetic process; GO:0006950 response to stress; GO:0016192 vesicle-mediated transport; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0002376 immune system process; GO:0043312 neutrophil degranulation; GO:0044238 primary metabolic process; GO:0002263 cell activation involved in immune response; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0009435 NAD biosynthetic process; GO:0002366 leukocyte activation involved in immune response; GO:0019365 pyridine nucleotide salvage; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0046497 nicotinate nucleotide metabolic process; GO:0001775 cell activation; GO:0019637 organophosphate metabolic process; GO:0051179 localization; GO:0006955 immune response; GO:0006887 exocytosis; GO:1901564 organonitrogen compound metabolic process; ","GO:0034774 secretory granule lumen; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0042582 azurophil granule; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016763 transferase activity, transferring pentosyl groups; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016874 ligase activity; GO:0016757 transferase activity, transferring glycosyl groups; GO:0004516 nicotinate phosphoribosyltransferase activity; GO:0005515 protein binding; GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity; GO:0016740 transferase activity; ","K00763","pncB; nicotinate phosphoribosyltransferase [EC:6.3.4.21]","hsa00760 Nicotinate and nicotinamide metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR002638; ","\"Quinolinate phosphoribosyl transferase, C-terminal; \"\r"]
["Q6YHK3","CD109 antigen OS=Homo sapiens OX=9606 GN=CD109","CD109",161.69,135.76,16.2,19,29,19,1.028,1.019,1.048,0.983,0.993,0.93,0.939,0.045,"endoplasmic reticulum\r","GO:0010837 regulation of keratinocyte proliferation; GO:1903845 negative regulation of cellular response to transforming growth factor beta stimulus; GO:0044237 cellular metabolic process; GO:0006949 syncytium formation; GO:0042157 lipoprotein metabolic process; GO:0008285 negative regulation of cell proliferation; GO:0010466 negative regulation of peptidase activity; GO:0008152 metabolic process; GO:0045682 regulation of epidermis development; GO:0050678 regulation of epithelial cell proliferation; GO:0032102 negative regulation of response to external stimulus; GO:0008544 epidermis development; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0052548 regulation of endopeptidase activity; GO:0042325 regulation of phosphorylation; GO:0043588 skin development; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0002520 immune system development; GO:0090287 regulation of cellular response to growth factor stimulus; GO:0031323 regulation of cellular metabolic process; GO:0043086 negative regulation of catalytic activity; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:0098773 skin epidermis development; GO:0030856 regulation of epithelial cell differentiation; GO:0048513 animal organ development; GO:0051336 regulation of hydrolase activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0006497 protein lipidation; GO:0001942 hair follicle development; GO:0050794 regulation of cellular process; GO:0043687 post-translational protein modification; GO:0044707 single-multicellular organism process; GO:0010951 negative regulation of endopeptidase activity; GO:0030316 osteoclast differentiation; GO:0042127 regulation of cell proliferation; GO:0042303 molting cycle; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0002576 platelet degranulation; GO:0045604 regulation of epidermal cell differentiation; GO:0080134 regulation of response to stress; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0051239 regulation of multicellular organismal process; GO:0009653 anatomical structure morphogenesis; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:1902578 single-organism localization; GO:0001933 negative regulation of protein phosphorylation; GO:0007275 multicellular organism development; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0009966 regulation of signal transduction; GO:0045861 negative regulation of proteolysis; GO:0048731 system development; GO:0000768 syncytium formation by plasma membrane fusion; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0032101 regulation of response to external stimulus; GO:0022405 hair cycle process; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0042633 hair cycle; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0045055 regulated exocytosis; GO:0061041 regulation of wound healing; GO:0051179 localization; GO:0043412 macromolecule modification; GO:0050793 regulation of developmental process; GO:1903034 regulation of response to wounding; GO:0045936 negative regulation of phosphate metabolic process; GO:0006887 exocytosis; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0031400 negative regulation of protein modification process; GO:0051234 establishment of localization; GO:0010646 regulation of cell communication; GO:0022404 molting cycle process; GO:0042158 lipoprotein biosynthetic process; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0009888 tissue development; GO:0002521 leukocyte differentiation; GO:0010605 negative regulation of macromolecule metabolic process; GO:1903035 negative regulation of response to wounding; GO:0072674 multinuclear osteoclast differentiation; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0032940 secretion by cell; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0045616 regulation of keratinocyte differentiation; GO:0044092 negative regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0036211 protein modification process; GO:0050680 negative regulation of epithelial cell proliferation; GO:0052547 regulation of peptidase activity; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0010839 negative regulation of keratinocyte proliferation; GO:0060255 regulation of macromolecule metabolic process; GO:0017015 regulation of transforming growth factor beta receptor signaling pathway; GO:0031324 negative regulation of cellular metabolic process; GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0051346 negative regulation of hydrolase activity; GO:0071704 organic substance metabolic process; GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0030154 cell differentiation; GO:0042326 negative regulation of phosphorylation; GO:0090288 negative regulation of cellular response to growth factor stimulus; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0006501 C-terminal protein lipidation; GO:0030099 myeloid cell differentiation; GO:0001932 regulation of protein phosphorylation; GO:0048585 negative regulation of response to stimulus; GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway; GO:0018410 C-terminal protein amino acid modification; GO:0061045 negative regulation of wound healing; GO:0044249 cellular biosynthetic process; GO:0030097 hemopoiesis; GO:0048534 hematopoietic or lymphoid organ development; GO:1903844 regulation of cellular response to transforming growth factor beta stimulus; GO:0034645 cellular macromolecule biosynthetic process; GO:0072675 osteoclast fusion; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0002573 myeloid leukocyte differentiation; GO:0010563 negative regulation of phosphorus metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005622 intracellular; GO:0044425 membrane part; GO:0044464 cell part; GO:0098805 whole membrane; GO:0099503 secretory vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0031092 platelet alpha granule membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0031225 anchored component of membrane; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0030667 secretory granule membrane; GO:0009986 cell surface; GO:0031091 platelet alpha granule; GO:0044444 cytoplasmic part; ","GO:0019955 cytokine binding; GO:0004867 serine-type endopeptidase inhibitor activity; GO:0030234 enzyme regulator activity; GO:0019838 growth factor binding; GO:0005488 binding; GO:0030414 peptidase inhibitor activity; GO:0061134 peptidase regulator activity; GO:0005515 protein binding; GO:0061135 endopeptidase regulator activity; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0004866 endopeptidase inhibitor activity; GO:0050431 transforming growth factor beta binding; ","K06530",null,null,"IPR002890; IPR011625; IPR009048; IPR014756; IPR008930; IPR001599; IPR019565; IPR011626; ","\"Alpha-2-macroglobulin, N-terminal; Alpha-2-macroglobulin, N-terminal 2; Alpha-macroglobulin, receptor-binding; Immunoglobulin E-set; Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid; Alpha-2-macroglobulin; Alpha-2-macroglobulin, thiol-ester bond-forming; Alpha-macroglobulin complement component; \"\r"]
["Q6ZMJ2","Scavenger receptor class A member 5 OS=Homo sapiens OX=9606 GN=SCARA5","SCARA5",53.994,44.931,19.2,9,11,9,1.087,1.061,1.302,0.797,1.026,0.861,0.778,0.0629,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0034755 iron ion transmembrane transport; GO:0065008 regulation of biological quality; GO:0044699 single-organism process; GO:0051234 establishment of localization; GO:0000041 transition metal ion transport; GO:0022607 cellular component assembly; GO:0009408 response to heat; GO:0065003 macromolecular complex assembly; GO:1900046 regulation of hemostasis; GO:0055065 metal ion homeostasis; GO:0051716 cellular response to stimulus; GO:0010468 regulation of gene expression; GO:0071822 protein complex subunit organization; GO:0098655 cation transmembrane transport; GO:0050801 ion homeostasis; GO:0044763 single-organism cellular process; GO:0098771 inorganic ion homeostasis; GO:0019725 cellular homeostasis; GO:0046916 cellular transition metal ion homeostasis; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0034605 cellular response to heat; GO:0048583 regulation of response to stimulus; GO:0019222 regulation of metabolic process; GO:0070271 protein complex biogenesis; GO:0098662 inorganic cation transmembrane transport; GO:0006879 cellular iron ion homeostasis; GO:0033554 cellular response to stress; GO:0016043 cellular component organization; GO:0055076 transition metal ion homeostasis; GO:0034220 ion transmembrane transport; GO:0051260 protein homooligomerization; GO:0009628 response to abiotic stimulus; GO:0030001 metal ion transport; GO:0060255 regulation of macromolecule metabolic process; GO:0030003 cellular cation homeostasis; GO:0030193 regulation of blood coagulation; GO:0055072 iron ion homeostasis; GO:0006826 iron ion transport; GO:0080134 regulation of response to stress; GO:0050896 response to stimulus; GO:0055082 cellular chemical homeostasis; GO:0051239 regulation of multicellular organismal process; GO:0051259 protein oligomerization; GO:0042592 homeostatic process; GO:0055080 cation homeostasis; GO:0006812 cation transport; GO:0009266 response to temperature stimulus; GO:0006898 receptor-mediated endocytosis; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0006461 protein complex assembly; GO:0050878 regulation of body fluid levels; GO:0070206 protein trimerization; GO:0006950 response to stress; GO:0098660 inorganic ion transmembrane transport; GO:0016192 vesicle-mediated transport; GO:0032101 regulation of response to external stimulus; GO:0006897 endocytosis; GO:0043933 macromolecular complex subunit organization; GO:0070207 protein homotrimerization; GO:0050818 regulation of coagulation; GO:0055085 transmembrane transport; GO:0061041 regulation of wound healing; GO:0006873 cellular ion homeostasis; GO:0006811 ion transport; GO:0006875 cellular metal ion homeostasis; GO:0051179 localization; GO:1903034 regulation of response to wounding; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0031226 intrinsic component of plasma membrane; GO:0044459 plasma membrane part; GO:0044425 membrane part; GO:0044464 cell part; GO:0071944 cell periphery; GO:0031224 intrinsic component of membrane; GO:0009986 cell surface; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; ","GO:0070287 ferritin receptor activity; GO:0038024 cargo receptor activity; GO:0005044 scavenger receptor activity; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; ",{"$nulls":3},"IPR017448; IPR001190; ","SRCR-like domain; SRCR domain; \r"]
["Q6ZRV2","Protein FAM83H OS=Homo sapiens OX=9606 GN=FAM83H","FAM83H",127.12,14.123,2.4,2,2,2,0.749,0.748,0.776,1.355,1.163,1.19,1.631,0.000579,"nucleus\r","GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0030335 positive regulation of cell migration; GO:0040017 positive regulation of locomotion; GO:0044699 single-organism process; GO:2000147 positive regulation of cell motility; GO:0032879 regulation of localization; GO:2000145 regulation of cell motility; GO:0031214 biomineral tissue development; GO:0007275 multicellular organism development; GO:0033365 protein localization to organelle; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0034613 cellular protein localization; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0032502 developmental process; GO:0009888 tissue development; GO:0045104 intermediate filament cytoskeleton organization; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0045103 intermediate filament-based process; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0030334 regulation of cell migration; GO:0051272 positive regulation of cellular component movement; GO:0032501 multicellular organismal process; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:1902589 single-organism organelle organization; GO:0048513 animal organ development; GO:0070727 cellular macromolecule localization; GO:0050789 regulation of biological process; GO:0044380 protein localization to cytoskeleton; GO:0044767 single-organism developmental process; GO:0006996 organelle organization; GO:0040012 regulation of locomotion; GO:0051179 localization; GO:0048856 anatomical structure development; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0005856 cytoskeleton; GO:0043226 organelle; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0043228 non-membrane-bounded organelle; ","GO:0019215 intermediate filament binding; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0019901 protein kinase binding; GO:0005515 protein binding; GO:1990254 keratin filament binding; GO:0019900 kinase binding; GO:0019899 enzyme binding; GO:0032403 protein complex binding; "]
["Q6ZVM7","TOM1-like protein 2 OS=Homo sapiens OX=9606 GN=TOM1L2","TOM1L2",55.556,16.044,9.1,4,7,4,1.075,1.052,1.044,0.966,0.962,1.001,0.924,0.00664,"nucleus\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0046907 intracellular transport; GO:0007346 regulation of mitotic cell cycle; GO:0045786 negative regulation of cell cycle; GO:0051129 negative regulation of cellular component organization; GO:0044699 single-organism process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:0010564 regulation of cell cycle process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0051783 regulation of nuclear division; GO:0045930 negative regulation of mitotic cell cycle; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0051784 negative regulation of nuclear division; GO:0006886 intracellular protein transport; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0034613 cellular protein localization; GO:0051726 regulation of cell cycle; GO:0009987 cellular process; GO:0051716 cellular response to stimulus; GO:0007088 regulation of mitotic nuclear division; GO:0033043 regulation of organelle organization; GO:0071702 organic substance transport; GO:0023052 signaling; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:0010639 negative regulation of organelle organization; GO:0070727 cellular macromolecule localization; GO:0010948 negative regulation of cell cycle process; GO:0050789 regulation of biological process; GO:0051128 regulation of cellular component organization; GO:0045839 negative regulation of mitotic nuclear division; GO:0051179 localization; GO:0065007 biological regulation; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0005622 intracellular; GO:0044464 cell part; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:0030276 clathrin binding; GO:0005515 protein binding; GO:0019900 kinase binding; GO:0019899 enzyme binding; GO:0005488 binding; GO:0019901 protein kinase binding; ",{"$nulls":3},"IPR002014; IPR004152; IPR008942; ","VHS domain; GAT domain; ENTH/VHS; \r"]
["Q709C8","Vacuolar protein sorting-associated protein 13C OS=Homo sapiens OX=9606 GN=VPS13C","VPS13C",422.39,35.639,4.6,16,19,15,1.023,1.122,1.074,0.922,0.971,0.943,0.881,0.0146,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0048193 Golgi vesicle transport; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0080134 regulation of response to stress; GO:0010821 regulation of mitochondrion organization; GO:1905089 regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization; GO:0051234 establishment of localization; GO:0051649 establishment of localization in cell; GO:0007005 mitochondrion organization; GO:0016482 cytosolic transport; GO:0009987 cellular process; GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization; GO:1901524 regulation of macromitophagy; GO:0006895 Golgi to endosome transport; GO:0031329 regulation of cellular catabolic process; GO:0016192 vesicle-mediated transport; GO:0009894 regulation of catabolic process; GO:0033043 regulation of organelle organization; GO:0048585 negative regulation of response to stimulus; GO:0031323 regulation of cellular metabolic process; GO:0010506 regulation of autophagy; GO:0051641 cellular localization; GO:0016241 regulation of macroautophagy; GO:0006810 transport; GO:0016197 endosomal transport; GO:0050789 regulation of biological process; GO:0080135 regulation of cellular response to stress; GO:1903146 regulation of mitophagy; GO:0006996 organelle organization; GO:0048583 regulation of response to stimulus; GO:0019222 regulation of metabolic process; GO:1905090 negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization; GO:0051128 regulation of cellular component organization; GO:0006892 post-Golgi vesicle-mediated transport; GO:0051179 localization; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0019867 outer membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0031968 organelle outer membrane; GO:0043227 membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0044429 mitochondrial part; GO:0005741 mitochondrial outer membrane; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031975 envelope; GO:0043230 extracellular organelle; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ",null,"K19525",null,null,"IPR031642; IPR015412; IPR009543; IPR031646; IPR031645; IPR026854; ","\"VPS13, repeated coiled region; Autophagy-related, C-terminal; Vacuolar protein sorting-associated protein 13, SHR-binding domain; Vacuolar protein sorting-associated protein 13, second N-terminal domain; Vacuolar protein sorting-associated protein 13, C-terminal; Vacuolar protein sorting-associated protein 13, N-terminal domain; \"\r"]
["Q70UQ0","Inhibitor of nuclear factor kappa-B kinase-interacting protein OS=Homo sapiens OX=9606 GN=IKBIP","IKBIP",39.309,5.4213,8,3,3,3,1.022,1.134,1.064,0.967,0.974,0.858,0.869,0.0509,"plasma membrane\r","GO:0010165 response to X-ray; GO:0009314 response to radiation; GO:0010212 response to ionizing radiation; GO:0050896 response to stimulus; GO:0009628 response to abiotic stimulus; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044432 endoplasmic reticulum part; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; "]
["Q71DI3","Histone H3.2 OS=Homo sapiens OX=9606 GN=HIST2H3A","HIST2H3A",15.388,10.999,24.3,5,9,2,0.93,0.859,0.924,1.082,1.093,1.107,1.21,1.92E-3,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0044699 single-organism process; GO:0051253 negative regulation of RNA metabolic process; GO:0044237 cellular metabolic process; GO:0009611 response to wounding; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0006334 nucleosome assembly; GO:0022607 cellular component assembly; GO:0009893 positive regulation of metabolic process; GO:0065003 macromolecular complex assembly; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0031497 chromatin assembly; GO:0071824 protein-DNA complex subunit organization; GO:0071103 DNA conformation change; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0006333 chromatin assembly or disassembly; GO:0010468 regulation of gene expression; GO:0045815 positive regulation of gene expression, epigenetic; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0000122 negative regulation of transcription from RNA polymerase II promoter; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0032501 multicellular organismal process; GO:0065004 protein-DNA complex assembly; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0031047 gene silencing by RNA; GO:1902679 negative regulation of RNA biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0045814 negative regulation of gene expression, epigenetic; GO:0006325 chromatin organization; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0050817 coagulation; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0034728 nucleosome organization; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0007599 hemostasis; GO:0071704 organic substance metabolic process; GO:0045892 negative regulation of transcription, DNA-templated; GO:0006342 chromatin silencing; GO:0006323 DNA packaging; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0009987 cellular process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0034622 cellular macromolecular complex assembly; GO:0050878 regulation of body fluid levels; GO:0006355 regulation of transcription, DNA-templated; GO:0006950 response to stress; GO:0010629 negative regulation of gene expression; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0000183 chromatin silencing at rDNA; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0009892 negative regulation of metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0040029 regulation of gene expression, epigenetic; GO:0016458 gene silencing; GO:0009890 negative regulation of biosynthetic process; GO:0051276 chromosome organization; GO:0042060 wound healing; GO:0006996 organelle organization; GO:0031327 negative regulation of cellular biosynthetic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0031982 vesicle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0000786 nucleosome; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0000785 chromatin; GO:0044464 cell part; GO:0005622 intracellular; GO:0005694 chromosome; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044815 DNA packaging complex; GO:0032993 protein-DNA complex; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0042393 histone binding; GO:0003677 DNA binding; GO:0046982 protein heterodimerization activity; GO:0005488 binding; GO:0046983 protein dimerization activity; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0003682 chromatin binding; ","K11253","H3; histone H3","hsa05322 Systemic lupus erythematosus - Homo sapiens (human); hsa05034 Alcoholism - Homo sapiens (human); hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human); ","IPR009072; IPR007125; ","Histone-fold; Histone H2A/H2B/H3; \r"]
["Q71UI9","Histone H2A.V OS=Homo sapiens OX=9606 GN=H2AFV","H2AFV",13.509,4.9794,20.3,3,14,1,1.241,1.093,1.111,0.88,0.851,0.884,0.759,0.00276,"nucleus\r","GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044699 single-organism process; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0051253 negative regulation of RNA metabolic process; GO:0045892 negative regulation of transcription, DNA-templated; GO:2001141 regulation of RNA biosynthetic process; GO:0006342 chromatin silencing; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0009987 cellular process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0010468 regulation of gene expression; GO:0006355 regulation of transcription, DNA-templated; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0010629 negative regulation of gene expression; GO:0044763 single-organism cellular process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0009892 negative regulation of metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051252 regulation of RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0040029 regulation of gene expression, epigenetic; GO:0016458 gene silencing; GO:0009890 negative regulation of biosynthetic process; GO:0050789 regulation of biological process; GO:0051276 chromosome organization; GO:0006996 organelle organization; GO:1902679 negative regulation of RNA biosynthetic process; GO:0019222 regulation of metabolic process; GO:0045814 negative regulation of gene expression, epigenetic; GO:0006325 chromatin organization; GO:0031327 negative regulation of cellular biosynthetic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; GO:2000112 regulation of cellular macromolecule biosynthetic process; ","GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0070013 intracellular organelle lumen; GO:0044454 nuclear chromosome part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0000790 nuclear chromatin; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0044815 DNA packaging complex; GO:0032993 protein-DNA complex; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005576 extracellular region; GO:0000786 nucleosome; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0000785 chromatin; GO:0000228 nuclear chromosome; GO:0043230 extracellular organelle; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003677 DNA binding; GO:0046982 protein heterodimerization activity; GO:0005488 binding; GO:0046983 protein dimerization activity; GO:0003676 nucleic acid binding; GO:0005515 protein binding; ","K11251","H2A; histone H2A","hsa05322 Systemic lupus erythematosus - Homo sapiens (human); hsa05034 Alcoholism - Homo sapiens (human); hsa04217 Necroptosis - Homo sapiens (human); ","IPR032454; IPR009072; IPR007125; ","\"Histone H2A, C-terminal domain; Histone-fold; Histone H2A/H2B/H3; \"\r"]
["Q7KZI7","Serine/threonine-protein kinase MARK2 OS=Homo sapiens OX=9606 GN=MARK2","MARK2",87.91,9.7387,6.9,5,6,5,0.935,0.971,0.988,0.949,1.087,1.07,1.073,0.206,"nucleus\r","GO:0044700 single organism signaling; GO:0032270 positive regulation of cellular protein metabolic process; GO:0007166 cell surface receptor signaling pathway; GO:0035088 establishment or maintenance of apical/basal cell polarity; GO:0006914 autophagy; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0044093 positive regulation of molecular function; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0051493 regulation of cytoskeleton organization; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0051347 positive regulation of transferase activity; GO:0016055 Wnt signaling pathway; GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:0031346 positive regulation of cell projection organization; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0048870 cell motility; GO:0007163 establishment or maintenance of cell polarity; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0000226 microtubule cytoskeleton organization; GO:0007267 cell-cell signaling; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0051094 positive regulation of developmental process; GO:0010975 regulation of neuron projection development; GO:0051640 organelle localization; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0016310 phosphorylation; GO:0018210 peptidyl-threonine modification; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0045597 positive regulation of cell differentiation; GO:0051239 regulation of multicellular organismal process; GO:0051646 mitochondrion localization; GO:0032147 activation of protein kinase activity; GO:0018107 peptidyl-threonine phosphorylation; GO:0051338 regulation of transferase activity; GO:0044248 cellular catabolic process; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0061245 establishment or maintenance of bipolar cell polarity; GO:0048731 system development; GO:0051960 regulation of nervous system development; GO:0060284 regulation of cell development; GO:0044238 primary metabolic process; GO:0007017 microtubule-based process; GO:0050770 regulation of axonogenesis; GO:0051247 positive regulation of protein metabolic process; GO:0010976 positive regulation of neuron projection development; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0006928 movement of cell or subcellular component; GO:0050769 positive regulation of neurogenesis; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:0043412 macromolecule modification; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0045666 positive regulation of neuron differentiation; GO:0051674 localization of cell; GO:0000422 mitophagy; GO:0048869 cellular developmental process; GO:1903008 organelle disassembly; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0006796 phosphate-containing compound metabolic process; GO:0051130 positive regulation of cellular component organization; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0007005 mitochondrion organization; GO:0046777 protein autophosphorylation; GO:0001764 neuron migration; GO:0010720 positive regulation of cell development; GO:0033674 positive regulation of kinase activity; GO:0032502 developmental process; GO:0045937 positive regulation of phosphate metabolic process; GO:0051962 positive regulation of nervous system development; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0198738 cell-cell signaling by wnt; GO:1902589 single-organism organelle organization; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0045664 regulation of neuron differentiation; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0040011 locomotion; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0043549 regulation of kinase activity; GO:2000026 regulation of multicellular organismal development; GO:0045859 regulation of protein kinase activity; GO:0016043 cellular component organization; GO:0016477 cell migration; GO:0060255 regulation of macromolecule metabolic process; GO:0031344 regulation of cell projection organization; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0006468 protein phosphorylation; GO:0030010 establishment of cell polarity; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0035556 intracellular signal transduction; GO:0044712 single-organism catabolic process; GO:0001932 regulation of protein phosphorylation; GO:0031401 positive regulation of protein modification process; GO:0033043 regulation of organelle organization; GO:0045860 positive regulation of protein kinase activity; GO:0001934 positive regulation of protein phosphorylation; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0051641 cellular localization; GO:0018193 peptidyl-amino acid modification; GO:0061726 mitochondrion disassembly; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0022411 cellular component disassembly; GO:0051128 regulation of cellular component organization; GO:0009056 catabolic process; GO:0022604 regulation of cell morphogenesis; GO:0050767 regulation of neurogenesis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0071944 cell periphery; GO:0097427 microtubule bundle; GO:0005737 cytoplasm; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005884 actin filament; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0015629 actin cytoskeleton; GO:0016328 lateral plasma membrane; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0099081 supramolecular polymer; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0050321 tau-protein kinase activity; GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0005515 protein binding; GO:0019207 kinase regulator activity; GO:0004672 protein kinase activity; GO:0098772 molecular function regulator; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0019209 kinase activator activity; GO:0016301 kinase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0045296 cadherin binding; GO:0008289 lipid binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016740 transferase activity; GO:0008047 enzyme activator activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0000287 magnesium ion binding; GO:0003723 RNA binding; GO:0005524 ATP binding; GO:0030295 protein kinase activator activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0019887 protein kinase regulator activity; GO:0000166 nucleotide binding; GO:0050839 cell adhesion molecule binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0030234 enzyme regulator activity; GO:0003676 nucleic acid binding; GO:0046872 metal ion binding; GO:0004674 protein serine/threonine kinase activity; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K08798",null,null,"IPR015940; IPR000719; IPR001772; IPR028375; IPR011009; ","\"Ubiquitin-associated domain; Protein kinase domain; Kinase associated domain 1 (KA1); KA1 domain/Ssp2, C-terminal; Protein kinase-like domain; \"\r"]
["Q7L1Q6","Basic leucine zipper and W2 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=BZW1","BZW1",48.043,30.223,22.2,11,14,10,0.883,0.844,0.883,1.155,1.125,1.122,1.303,1.17E-4,"nucleus\r","GO:0050794 regulation of cellular process; GO:0006725 cellular aromatic compound metabolic process; GO:0097659 nucleic acid-templated transcription; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0006355 regulation of transcription, DNA-templated; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0044238 primary metabolic process; GO:0051252 regulation of RNA metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0034645 cellular macromolecule biosynthetic process; GO:0090304 nucleic acid metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006351 transcription, DNA-templated; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0010467 gene expression; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0050839 cell adhesion molecule binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; ",{"$nulls":3},"IPR003307; IPR016024; IPR016021; ","W2 domain; Armadillo-type fold; MIF4G-like domain; \r"]
["Q7L2H7","Eukaryotic translation initiation factor 3 subunit M OS=Homo sapiens OX=9606 GN=EIF3M","EIF3M",42.502,76.677,20.6,7,10,7,0.893,0.893,0.758,1.081,1.15,1.199,1.348,0.0085,"cytoplasm\r","GO:0006518 peptide metabolic process; GO:0043043 peptide biosynthetic process; GO:0044267 cellular protein metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0009058 biosynthetic process; GO:0043603 cellular amide metabolic process; GO:0044238 primary metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0002181 cytoplasmic translation; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0006413 translational initiation; GO:0034641 cellular nitrogen compound metabolic process; GO:0010467 gene expression; GO:0043170 macromolecule metabolic process; GO:0043604 amide biosynthetic process; GO:0019538 protein metabolic process; GO:0006412 translation; GO:0009059 macromolecule biosynthetic process; GO:0002183 cytoplasmic translational initiation; GO:0009987 cellular process; GO:1901564 organonitrogen compound metabolic process; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0043234 protein complex; GO:0005623 cell; GO:0044444 cytoplasmic part; GO:0005852 eukaryotic translation initiation factor 3 complex; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0008135 translation factor activity, RNA binding; GO:0031369 translation initiation factor binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0003743 translation initiation factor activity; GO:0005515 protein binding; ","K15030",null,null,"IPR000717; IPR011991; IPR016024; ","Proteasome component (PCI) domain; Winged helix-turn-helix DNA-binding domain; Armadillo-type fold; \r"]
["Q7L5L3","Lysophospholipase D GDPD3 OS=Homo sapiens OX=9606 GN=GDPD3","GDPD3",36.596,12.997,10.4,2,2,2,0.987,0.958,0.945,1.033,1.045,1.036,1.078,0.00492,"extracellular\r","GO:0044699 single-organism process; GO:0008152 metabolic process; GO:0044238 primary metabolic process; GO:0044710 single-organism metabolic process; GO:0006629 lipid metabolic process; GO:0071704 organic substance metabolic process; ","GO:0016020 membrane; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0044425 membrane part; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0031224 intrinsic component of membrane; GO:0043227 membrane-bounded organelle; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:0042578 phosphoric ester hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0043167 ion binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0016787 hydrolase activity; GO:0008081 phosphoric diester hydrolase activity; ",{"$nulls":3},"IPR030395; IPR017946; ","\"Glycerophosphodiester phosphodiesterase domain; PLC-like phosphodiesterase, TIM beta/alpha-barrel domain; \"\r"]
["Q7L775","EPM2A-interacting protein 1 OS=Homo sapiens OX=9606 GN=EPM2AIP1","EPM2AIP1",70.369,15.587,3.3,2,2,2,0.935,1.025,1.029,1.11,0.969,0.944,1.011,0.877,"cytoplasm\r","GO:0043467 regulation of generation of precursor metabolites and energy; GO:0045913 positive regulation of carbohydrate metabolic process; GO:0050794 regulation of cellular process; GO:0043255 regulation of carbohydrate biosynthetic process; GO:0032885 regulation of polysaccharide biosynthetic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0009891 positive regulation of biosynthetic process; GO:1901700 response to oxygen-containing compound; GO:0010906 regulation of glucose metabolic process; GO:0050896 response to stimulus; GO:2001141 regulation of RNA biosynthetic process; GO:0010962 regulation of glucan biosynthetic process; GO:0009893 positive regulation of metabolic process; GO:0009889 regulation of biosynthetic process; GO:0044093 positive regulation of molecular function; GO:0051338 regulation of transferase activity; GO:2000465 regulation of glycogen (starch) synthase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0009719 response to endogenous stimulus; GO:0045725 positive regulation of glycogen biosynthetic process; GO:0051347 positive regulation of transferase activity; GO:1901652 response to peptide; GO:0070875 positive regulation of glycogen metabolic process; GO:0010468 regulation of gene expression; GO:0006355 regulation of transcription, DNA-templated; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0010675 regulation of cellular carbohydrate metabolic process; GO:0048522 positive regulation of cellular process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0010676 positive regulation of cellular carbohydrate metabolic process; GO:0010033 response to organic substance; GO:0032881 regulation of polysaccharide metabolic process; GO:0006109 regulation of carbohydrate metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0043085 positive regulation of catalytic activity; GO:0010907 positive regulation of glucose metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0010243 response to organonitrogen compound; GO:0032868 response to insulin; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0043434 response to peptide hormone; GO:0050790 regulation of catalytic activity; GO:0070873 regulation of glycogen metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:1901698 response to nitrogen compound; GO:0065009 regulation of molecular function; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0005979 regulation of glycogen biosynthetic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0009725 response to hormone; GO:2000467 positive regulation of glycogen (starch) synthase activity; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0005783 endoplasmic reticulum; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031974 membrane-enclosed lumen; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding; GO:0003677 DNA binding; GO:0042802 identical protein binding; GO:0005488 binding; GO:0001071 nucleic acid binding transcription factor activity; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0003700 transcription factor activity, sequence-specific DNA binding; "]
["Q7LG56","Ribonucleoside-diphosphate reductase subunit M2 B OS=Homo sapiens OX=9606 GN=RRM2B","RRM2B",40.736,6.2383,4,1,1,1,1.059,0.979,1.036,0.954,1.068,0.914,0.955,0.412,"cytoplasm\r","GO:0010941 regulation of cell death; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0009262 deoxyribonucleotide metabolic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0014075 response to amine; GO:0009263 deoxyribonucleotide biosynthetic process; GO:2001233 regulation of apoptotic signaling pathway; GO:0008152 metabolic process; GO:0010646 regulation of cell communication; GO:2001243 negative regulation of intrinsic apoptotic signaling pathway; GO:1901137 carbohydrate derivative biosynthetic process; GO:0006753 nucleoside phosphate metabolic process; GO:0007005 mitochondrion organization; GO:0006979 response to oxidative stress; GO:0009719 response to endogenous stimulus; GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator; GO:0043170 macromolecule metabolic process; GO:0006261 DNA-dependent DNA replication; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0032501 multicellular organismal process; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0090407 organophosphate biosynthetic process; GO:0010243 response to organonitrogen compound; GO:0048513 animal organ development; GO:0001655 urogenital system development; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:1902532 negative regulation of intracellular signal transduction; GO:0090304 nucleic acid metabolic process; GO:1902253 regulation of intrinsic apoptotic signaling pathway by p53 class mediator; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0044260 cellular macromolecule metabolic process; GO:0060548 negative regulation of cell death; GO:0048856 anatomical structure development; GO:1901362 organic cyclic compound biosynthetic process; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0033554 cellular response to stress; GO:0043069 negative regulation of programmed cell death; GO:0006260 DNA replication; GO:0009165 nucleotide biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0006259 DNA metabolic process; GO:0015949 nucleobase-containing small molecule interconversion; GO:0043067 regulation of programmed cell death; GO:0032042 mitochondrial DNA metabolic process; GO:0072001 renal system development; GO:0009200 deoxyribonucleoside triphosphate metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0046483 heterocycle metabolic process; GO:0043066 negative regulation of apoptotic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:1901796 regulation of signal transduction by p53 class mediator; GO:0006264 mitochondrial DNA replication; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0000002 mitochondrial genome maintenance; GO:0009059 macromolecule biosynthetic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:1901797 negative regulation of signal transduction by p53 class mediator; GO:0001822 kidney development; GO:1902531 regulation of intracellular signal transduction; GO:0003008 system process; GO:0006950 response to stress; GO:0044711 single-organism biosynthetic process; GO:0048731 system development; GO:0003014 renal system process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0048585 negative regulation of response to stimulus; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0006974 cellular response to DNA damage stimulus; GO:0006281 DNA repair; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:2001242 regulation of intrinsic apoptotic signaling pathway; GO:0019637 organophosphate metabolic process; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0016725 oxidoreductase activity, acting on CH or CH2 groups; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0061731 ribonucleoside-diphosphate reductase activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; GO:0005515 protein binding; GO:0016728 oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor; GO:0016491 oxidoreductase activity; ","K10808","RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]","hsa00230 Purine metabolism - Homo sapiens (human); hsa00480 Glutathione metabolism - Homo sapiens (human); hsa00983 Drug metabolism - other enzymes - Homo sapiens (human); hsa00240 Pyrimidine metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa04115 p53 signaling pathway - Homo sapiens (human); ","IPR012348; IPR009078; ","Ribonucleotide reductase-related; Ferritin-like superfamily; \r"]
["Q7RTV0","PHD finger-like domain-containing protein 5A OS=Homo sapiens OX=9606 GN=PHF5A","PHF5A",12.405,4.7599,29.1,4,4,4,0.917,0.994,1.103,1.121,0.926,1.06,1.031,0.719,"extracellular\r","GO:0097659 nucleic acid-templated transcription; GO:0009891 positive regulation of biosynthetic process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0006396 RNA processing; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0019222 regulation of metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0000375 RNA splicing, via transesterification reactions; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0008380 RNA splicing; GO:0051254 positive regulation of RNA metabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0031325 positive regulation of cellular metabolic process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0010467 gene expression; GO:0031328 positive regulation of cellular biosynthetic process; GO:0065007 biological regulation; ","GO:0005686 U2 snRNP; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0071011 precatalytic spliceosome; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0005689 U12-type spliceosomal complex; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005681 spliceosomal complex; GO:0097525 spliceosomal snRNP complex; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0016363 nuclear matrix; GO:0071013 catalytic step 2 spliceosome; GO:1990904 ribonucleoprotein complex; GO:0034399 nuclear periphery; GO:0030532 small nuclear ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003677 DNA binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0001071 nucleic acid binding transcription factor activity; GO:0003676 nucleic acid binding; GO:0003700 transcription factor activity, sequence-specific DNA binding; ","K12834","PHF5A; PHD finger-like domain-containing protein 5A","hsa03040 Spliceosome - Homo sapiens (human); "]
["Q7Z3B4","Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54","NUP54",55.435,14.246,10.7,5,5,5,0.917,0.915,0.835,1.152,0.972,1.207,1.249,0.0394,"cytoplasm\r","GO:0050658 RNA transport; GO:0044085 cellular component biogenesis; GO:1903533 regulation of protein targeting; GO:0051169 nuclear transport; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:1902583 multi-organism intracellular transport; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0032879 regulation of localization; GO:0015931 nucleobase-containing compound transport; GO:0065003 macromolecular complex assembly; GO:0033365 protein localization to organelle; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0075733 intracellular transport of virus; GO:0044419 interspecies interaction between organisms; GO:0006606 protein import into nucleus; GO:0008104 protein localization; GO:0051031 tRNA transport; GO:0044765 single-organism transport; GO:0007077 mitotic nuclear envelope disassembly; GO:0000278 mitotic cell cycle; GO:0018130 heterocycle biosynthetic process; GO:0072657 protein localization to membrane; GO:0044763 single-organism cellular process; GO:0032774 RNA biosynthetic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0006611 protein export from nucleus; GO:0051704 multi-organism process; GO:0051291 protein heterooligomerization; GO:0006810 transport; GO:0080135 regulation of cellular response to stress; GO:0031047 gene silencing by RNA; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0051223 regulation of protein transport; GO:0006913 nucleocytoplasmic transport; GO:0006464 cellular protein modification process; GO:1901362 organic cyclic compound biosynthetic process; GO:0050794 regulation of cellular process; GO:0016925 protein sumoylation; GO:0046907 intracellular transport; GO:0051260 protein homooligomerization; GO:0051028 mRNA transport; GO:1902593 single-organism nuclear import; GO:0044267 cellular protein metabolic process; GO:0080134 regulation of response to stress; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0051236 establishment of RNA localization; GO:0060341 regulation of cellular localization; GO:0051259 protein oligomerization; GO:0046483 heterocycle metabolic process; GO:1902578 single-organism localization; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0051081 nuclear envelope disassembly; GO:0044744 protein targeting to nucleus; GO:1902580 single-organism cellular localization; GO:0032880 regulation of protein localization; GO:0034613 cellular protein localization; GO:0090150 establishment of protein localization to membrane; GO:0006461 protein complex assembly; GO:0046794 transport of virus; GO:0006403 RNA localization; GO:0006405 RNA export from nucleus; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0044766 multi-organism transport; GO:0045184 establishment of protein localization; GO:0006409 tRNA export from nucleus; GO:0046822 regulation of nucleocytoplasmic transport; GO:0032446 protein modification by small protein conjugation; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0036228 protein targeting to nuclear inner membrane; GO:0043412 macromolecule modification; GO:0051179 localization; GO:1903827 regulation of cellular protein localization; GO:0006607 NLS-bearing protein import into nucleus; GO:0010256 endomembrane system organization; GO:0072594 establishment of protein localization to organelle; GO:0017038 protein import; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:1902581 multi-organism cellular localization; GO:0051168 nuclear export; GO:0044764 multi-organism cellular process; GO:0051234 establishment of localization; GO:0071431 tRNA-containing ribonucleoprotein complex export from nucleus; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0042306 regulation of protein import into nucleus; GO:0071427 mRNA-containing ribonucleoprotein complex export from nucleus; GO:0051649 establishment of localization in cell; GO:0022607 cellular component assembly; GO:0050657 nucleic acid transport; GO:0051262 protein tetramerization; GO:0051290 protein heterotetramerization; GO:0033036 macromolecule localization; GO:0010827 regulation of glucose transport; GO:0010468 regulation of gene expression; GO:0071822 protein complex subunit organization; GO:0006999 nuclear pore organization; GO:1901360 organic cyclic compound metabolic process; GO:0032386 regulation of intracellular transport; GO:0070647 protein modification by small protein conjugation or removal; GO:0010605 negative regulation of macromolecule metabolic process; GO:1902582 single-organism intracellular transport; GO:0071166 ribonucleoprotein complex localization; GO:0016070 RNA metabolic process; GO:0050789 regulation of biological process; GO:0030397 membrane disassembly; GO:0090304 nucleic acid metabolic process; GO:1900180 regulation of protein localization to nucleus; GO:1900034 regulation of cellular response to heat; GO:0019222 regulation of metabolic process; GO:0019083 viral transcription; GO:0036211 protein modification process; GO:0070271 protein complex biogenesis; GO:0016043 cellular component organization; GO:1902579 multi-organism localization; GO:0006997 nucleus organization; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:1904589 regulation of protein import; GO:0070201 regulation of establishment of protein localization; GO:0071704 organic substance metabolic process; GO:0006998 nuclear envelope organization; GO:0018205 peptidyl-lysine modification; GO:0016032 viral process; GO:0019080 viral gene expression; GO:0006886 intracellular protein transport; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0033157 regulation of intracellular protein transport; GO:0006406 mRNA export from nucleus; GO:0070206 protein trimerization; GO:0010629 negative regulation of gene expression; GO:0051049 regulation of transport; GO:0006807 nitrogen compound metabolic process; GO:0044802 single-organism membrane organization; GO:0070208 protein heterotrimerization; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0051641 cellular localization; GO:0018193 peptidyl-amino acid modification; GO:0016458 gene silencing; GO:0070727 cellular macromolecule localization; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0051170 nuclear import; GO:0071426 ribonucleoprotein complex export from nucleus; GO:0022411 cellular component disassembly; GO:0010467 gene expression; GO:0022402 cell cycle process; GO:0034504 protein localization to nucleus; GO:0090435 protein localization to nuclear envelope; GO:0071705 nitrogen compound transport; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005643 nuclear pore; GO:0031090 organelle membrane; GO:0005635 nuclear envelope; GO:0044613 nuclear pore central transport channel; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0032991 macromolecular complex; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031965 nuclear membrane; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:0031975 envelope; GO:0043227 membrane-bounded organelle; GO:0043234 protein complex; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0005487 nucleocytoplasmic transporter activity; GO:0017056 structural constituent of nuclear pore; GO:0005198 structural molecule activity; GO:0005488 binding; GO:0005215 transporter activity; ","K14308","NUP54; nuclear pore complex protein Nup54","hsa03013 RNA transport - Homo sapiens (human); ","IPR025712; ","\"Nucleoporin Nup54, alpha-helical domain; \"\r"]
["Q7Z3D6","D-glutamate cyclase, mitochondrial OS=Homo sapiens OX=9606 GN=DGLUCY","DGLUCY",66.436,37.72,18.5,8,9,8,1.129,1.017,1.087,0.911,0.932,0.944,0.862,0.0102,"mitochondria\r",null,"GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR025504; ","Domain of unknown function DUF4392; \r"]
["Q7Z3U7","Protein MON2 homolog OS=Homo sapiens OX=9606 GN=MON2","MON2",190.36,27.114,4.9,8,10,8,1.084,0.976,0.935,1.059,0.911,1.048,1.008,0.917,"plasma membrane\r","GO:0046907 intracellular transport; GO:0006895 Golgi to endosome transport; GO:0016192 vesicle-mediated transport; GO:0048193 Golgi vesicle transport; GO:0071702 organic substance transport; GO:0015031 protein transport; GO:0051641 cellular localization; GO:0051234 establishment of localization; GO:0006810 transport; GO:0016197 endosomal transport; GO:0045184 establishment of protein localization; GO:0051649 establishment of localization in cell; GO:0008104 protein localization; GO:0051179 localization; GO:0016482 cytosolic transport; GO:0006892 post-Golgi vesicle-mediated transport; GO:0033036 macromolecule localization; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR032817; IPR011989; IPR032691; IPR032629; IPR016024; IPR015403; ","\"Mon2, C-terminal; Armadillo-like helical; Guanine nucleotide exchange factor, N-terminal; Mon2, dimerisation and cyclophilin-binding domain; Armadillo-type fold; Sec7, C-terminal; \"\r"]
["Q7Z434","Mitochondrial antiviral-signaling protein OS=Homo sapiens OX=9606 GN=MAVS","MAVS",56.527,4.7649,6.7,3,3,3,1.027,1.013,1.008,0.968,0.982,1.012,0.972,0.114,"cytoplasm\r","GO:0044700 single organism signaling; GO:0032481 positive regulation of type I interferon production; GO:0032270 positive regulation of cellular protein metabolic process; GO:0032680 regulation of tumor necrosis factor production; GO:1903533 regulation of protein targeting; GO:0032647 regulation of interferon-alpha production; GO:0098542 defense response to other organism; GO:0009891 positive regulation of biosynthetic process; GO:0032760 positive regulation of tumor necrosis factor production; GO:0031347 regulation of defense response; GO:0044237 cellular metabolic process; GO:0009607 response to biotic stimulus; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling; GO:0044093 positive regulation of molecular function; GO:0060340 positive regulation of type I interferon-mediated signaling pathway; GO:0030522 intracellular receptor signaling pathway; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0039529 RIG-I signaling pathway; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0044419 interspecies interaction between organisms; GO:0014070 response to organic cyclic compound; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0051174 regulation of phosphorus metabolic process; GO:0002758 innate immune response-activating signal transduction; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0060760 positive regulation of response to cytokine stimulus; GO:0071658 regulation of IP-10 production; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0031323 regulation of cellular metabolic process; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:1903506 regulation of nucleic acid-templated transcription; GO:0051090 regulation of sequence-specific DNA binding transcription factor activity; GO:0060759 regulation of response to cytokine stimulus; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051223 regulation of protein transport; GO:0006464 cellular protein modification process; GO:0002682 regulation of immune system process; GO:0042307 positive regulation of protein import into nucleus; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0032677 regulation of interleukin-8 production; GO:0002753 cytoplasmic pattern recognition receptor signaling pathway; GO:0001819 positive regulation of cytokine production; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0033158 regulation of protein import into nucleus, translocation; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:0051239 regulation of multicellular organismal process; GO:1903901 negative regulation of viral life cycle; GO:0060341 regulation of cellular localization; GO:0042990 regulation of transcription factor import into nucleus; GO:0050688 regulation of defense response to virus; GO:0031349 positive regulation of defense response; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0032880 regulation of protein localization; GO:0009966 regulation of signal transduction; GO:0050778 positive regulation of immune response; GO:0009617 response to bacterium; GO:0071359 cellular response to dsRNA; GO:0002253 activation of immune response; GO:0051254 positive regulation of RNA metabolic process; GO:1902531 regulation of intracellular signal transduction; GO:0006950 response to stress; GO:0032648 regulation of interferon-beta production; GO:0043900 regulation of multi-organism process; GO:1900063 regulation of peroxisome organization; GO:0001961 positive regulation of cytokine-mediated signaling pathway; GO:1903557 positive regulation of tumor necrosis factor superfamily cytokine production; GO:0032101 regulation of response to external stimulus; GO:0071407 cellular response to organic cyclic compound; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0045071 negative regulation of viral genome replication; GO:0044238 primary metabolic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:1900182 positive regulation of protein localization to nucleus; GO:0033160 positive regulation of protein import into nucleus, translocation; GO:0051247 positive regulation of protein metabolic process; GO:0032727 positive regulation of interferon-alpha production; GO:0046822 regulation of nucleocytoplasmic transport; GO:1904951 positive regulation of establishment of protein localization; GO:0031325 positive regulation of cellular metabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0048584 positive regulation of response to stimulus; GO:0043412 macromolecule modification; GO:0006955 immune response; GO:0002230 positive regulation of defense response to virus by host; GO:1903827 regulation of cellular protein localization; GO:1904591 positive regulation of protein import; GO:0070646 protein modification by small protein removal; GO:1903555 regulation of tumor necrosis factor superfamily cytokine production; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0001818 negative regulation of cytokine production; GO:0039528 cytoplasmic pattern recognition receptor signaling pathway in response to virus; GO:2001141 regulation of RNA biosynthetic process; GO:0042306 regulation of protein import into nucleus; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0045088 regulation of innate immune response; GO:0009893 positive regulation of metabolic process; GO:0032642 regulation of chemokine production; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0046824 positive regulation of nucleocytoplasmic transport; GO:0002221 pattern recognition receptor signaling pathway; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0050691 regulation of defense response to virus by host; GO:0002697 regulation of immune effector process; GO:0098586 cellular response to virus; GO:0070887 cellular response to chemical stimulus; GO:0048525 negative regulation of viral process; GO:0010468 regulation of gene expression; GO:0045937 positive regulation of phosphate metabolic process; GO:0031326 regulation of cellular biosynthetic process; GO:0043331 response to dsRNA; GO:0048522 positive regulation of cellular process; GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity; GO:0032386 regulation of intracellular transport; GO:0045069 regulation of viral genome replication; GO:0070647 protein modification by small protein conjugation or removal; GO:0023052 signaling; GO:0002764 immune response-regulating signaling pathway; GO:0051050 positive regulation of transport; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0051607 defense response to virus; GO:1901699 cellular response to nitrogen compound; GO:1900180 regulation of protein localization to nucleus; GO:0065009 regulation of molecular function; GO:0071649 regulation of chemokine (C-C motif) ligand 5 production; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0006952 defense response; GO:0060338 regulation of type I interferon-mediated signaling pathway; GO:0036211 protein modification process; GO:0051222 positive regulation of protein transport; GO:0032722 positive regulation of chemokine production; GO:0009615 response to virus; GO:0002218 activation of innate immune response; GO:0032479 regulation of type I interferon production; GO:0002831 regulation of response to biotic stimulus; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0090316 positive regulation of intracellular protein transport; GO:0002252 immune effector process; GO:1903829 positive regulation of cellular protein localization; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0001959 regulation of cytokine-mediated signaling pathway; GO:1904589 regulation of protein import; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0016579 protein deubiquitination; GO:0051707 response to other organism; GO:0070201 regulation of establishment of protein localization; GO:0045087 innate immune response; GO:0071704 organic substance metabolic process; GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production; GO:0032757 positive regulation of interleukin-8 production; GO:0016032 viral process; GO:0023056 positive regulation of signaling; GO:0002757 immune response-activating signal transduction; GO:0006508 proteolysis; GO:0010647 positive regulation of cell communication; GO:0033157 regulation of intracellular protein transport; GO:0009987 cellular process; GO:0042993 positive regulation of transcription factor import into nucleus; GO:0045089 positive regulation of innate immune response; GO:0006355 regulation of transcription, DNA-templated; GO:0043330 response to exogenous dsRNA; GO:0042742 defense response to bacterium; GO:0035556 intracellular signal transduction; GO:0051049 regulation of transport; GO:0032388 positive regulation of intracellular transport; GO:0001932 regulation of protein phosphorylation; GO:0050792 regulation of viral process; GO:0031401 positive regulation of protein modification process; GO:0033043 regulation of organelle organization; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0071660 positive regulation of IP-10 production; GO:0001934 positive regulation of protein phosphorylation; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0043901 negative regulation of multi-organism process; GO:0032728 positive regulation of interferon-beta production; GO:0071360 cellular response to exogenous dsRNA; GO:0051246 regulation of protein metabolic process; GO:0002684 positive regulation of immune system process; GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling; GO:0001817 regulation of cytokine production; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0051128 regulation of cellular component organization; GO:0009967 positive regulation of signal transduction; GO:1903900 regulation of viral life cycle; GO:0032480 negative regulation of type I interferon production; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0019867 outer membrane; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044438 microbody part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005778 peroxisomal membrane; GO:0005740 mitochondrial envelope; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0042579 microbody; GO:0098805 whole membrane; GO:0031968 organelle outer membrane; GO:0043227 membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0031903 microbody membrane; GO:0044439 peroxisomal part; GO:0098588 bounding membrane of organelle; GO:0044429 mitochondrial part; GO:0005777 peroxisome; GO:0005741 mitochondrial outer membrane; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0016021 integral component of membrane; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031975 envelope; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0005488 binding; GO:0019901 protein kinase binding; GO:0050700 CARD domain binding; GO:0005515 protein binding; GO:0019904 protein domain specific binding; GO:0019900 kinase binding; GO:0004871 signal transducer activity; GO:0019899 enzyme binding; ","K12648","MAVS; mitochondrial antiviral-signaling protein","hsa05168 Herpes simplex infection - Homo sapiens (human); hsa05160 Hepatitis C - Homo sapiens (human); hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human); hsa05162 Measles - Homo sapiens (human); hsa04623 Cytosolic DNA-sensing pathway - Homo sapiens (human); hsa05161 Hepatitis B - Homo sapiens (human); hsa04622 RIG-I-like receptor signaling pathway - Homo sapiens (human); hsa05164 Influenza A - Homo sapiens (human); ","IPR031964; ","Caspase recruitment domain; \r"]
["Q7Z4G4","tRNA (guanine(10)-N2)-methyltransferase homolog OS=Homo sapiens OX=9606 GN=TRMT11","TRMT11",53.42,11.4,5.8,2,2,2,0.904,0.989,1.066,1.063,0.797,1.185,1.029,0.898,"cytoplasm\r","GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0006725 cellular aromatic compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0009451 RNA modification; GO:0032259 methylation; GO:0071704 organic substance metabolic process; GO:0016070 RNA metabolic process; GO:0008152 metabolic process; GO:0006399 tRNA metabolic process; GO:0030488 tRNA methylation; GO:0090304 nucleic acid metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0043414 macromolecule methylation; GO:0008033 tRNA processing; GO:0044260 cellular macromolecule metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0010467 gene expression; GO:0043170 macromolecule metabolic process; GO:0001510 RNA methylation; GO:0043412 macromolecule modification; GO:0006400 tRNA modification; GO:0009987 cellular process; GO:0034660 ncRNA metabolic process; ",null,"GO:0003723 RNA binding; GO:0008757 S-adenosylmethionine-dependent methyltransferase activity; GO:0008168 methyltransferase activity; GO:0016741 transferase activity, transferring one-carbon groups; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0008173 RNA methyltransferase activity; GO:0003824 catalytic activity; GO:0000049 tRNA binding; GO:0016423 tRNA (guanine) methyltransferase activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0004809 tRNA (guanine-N2-)-methyltransferase activity; GO:0008175 tRNA methyltransferase activity; GO:0008170 N-methyltransferase activity; GO:0016740 transferase activity; ","K15430",null,null,"IPR000241; IPR029063; ","Putative RNA methylase domain; S-adenosyl-L-methionine-dependent methyltransferase; \r"]
["Q7Z4H8","KDEL motif-containing protein 2 OS=Homo sapiens OX=9606 GN=KDELC2","KDELC2",58.572,25.985,8.3,3,3,3,1.123,1.108,1.169,0.951,0.797,0.88,0.773,0.00834,"mitochondria\r","GO:0008152 metabolic process; GO:1903509 liposaccharide metabolic process; GO:0006643 membrane lipid metabolic process; GO:0044710 single-organism metabolic process; GO:0044763 single-organism cellular process; GO:0006664 glycolipid metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0009987 cellular process; GO:0006629 lipid metabolic process; GO:0071704 organic substance metabolic process; ","GO:0005788 endoplasmic reticulum lumen; GO:0043229 intracellular organelle; GO:0005783 endoplasmic reticulum; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044432 endoplasmic reticulum part; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0046527 glucosyltransferase activity; GO:0005515 protein binding; GO:0016757 transferase activity, transferring glycosyl groups; GO:0016758 transferase activity, transferring hexosyl groups; GO:0003824 catalytic activity; GO:0016740 transferase activity; GO:0005488 binding; ",{"$nulls":3},"IPR013783; IPR014756; ","Immunoglobulin-like fold; Immunoglobulin E-set; \r"]
["Q7Z5L9","Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2","IRF2BP2",61.024,13.542,4.9,2,2,2,1.011,1.046,0.84,1.024,1.091,0.996,1.074,0.364,"nucleus\r","GO:0050794 regulation of cellular process; GO:0006725 cellular aromatic compound metabolic process; GO:0097659 nucleic acid-templated transcription; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0006355 regulation of transcription, DNA-templated; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0044238 primary metabolic process; GO:0051252 regulation of RNA metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0034645 cellular macromolecule biosynthetic process; GO:0090304 nucleic acid metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006351 transcription, DNA-templated; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0010467 gene expression; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005488 binding; GO:0043167 ion binding; ",{"$nulls":3},"IPR022750; ","\"Interferon regulatory factor 2-binding protein 1 & 2, zinc finger; \"\r"]
["Q7Z6K5","Arpin OS=Homo sapiens OX=9606 GN=ARPIN","ARPIN",24.943,2.8869,6.6,2,2,2,1.13,0.94,0.885,0.983,1.004,1.067,1.034,0.651,"mitochondria\r","GO:0030833 regulation of actin filament polymerization; GO:0050794 regulation of cellular process; GO:0051093 negative regulation of developmental process; GO:0016043 cellular component organization; GO:0065008 regulation of biological quality; GO:1902744 negative regulation of lamellipodium organization; GO:0032956 regulation of actin cytoskeleton organization; GO:0051129 negative regulation of cellular component organization; GO:2000393 negative regulation of lamellipodium morphogenesis; GO:0044699 single-organism process; GO:0031344 regulation of cell projection organization; GO:0044087 regulation of cellular component biogenesis; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0030832 regulation of actin filament length; GO:0040013 negative regulation of locomotion; GO:1902743 regulation of lamellipodium organization; GO:2000145 regulation of cell motility; GO:0032879 regulation of localization; GO:0032535 regulation of cellular component size; GO:0031345 negative regulation of cell projection organization; GO:0032271 regulation of protein polymerization; GO:0033058 directional locomotion; GO:0051493 regulation of cytoskeleton organization; GO:0009987 cellular process; GO:0051270 regulation of cellular component movement; GO:0051125 regulation of actin nucleation; GO:0051494 negative regulation of cytoskeleton organization; GO:0044763 single-organism cellular process; GO:0051126 negative regulation of actin nucleation; GO:0033043 regulation of organelle organization; GO:0030334 regulation of cell migration; GO:0032970 regulation of actin filament-based process; GO:2000146 negative regulation of cell motility; GO:0010639 negative regulation of organelle organization; GO:0008064 regulation of actin polymerization or depolymerization; GO:0043254 regulation of protein complex assembly; GO:0050789 regulation of biological process; GO:0030336 negative regulation of cell migration; GO:0022603 regulation of anatomical structure morphogenesis; GO:1902904 negative regulation of supramolecular fiber organization; GO:0090066 regulation of anatomical structure size; GO:0040011 locomotion; GO:0051128 regulation of cellular component organization; GO:0040012 regulation of locomotion; GO:0050793 regulation of developmental process; GO:0022604 regulation of cell morphogenesis; GO:2000392 regulation of lamellipodium morphogenesis; GO:0051271 negative regulation of cellular component movement; GO:1902903 regulation of supramolecular fiber organization; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0031252 cell leading edge; GO:0042995 cell projection; GO:0005623 cell; GO:0044464 cell part; GO:0030027 lamellipodium; ","GO:0005515 protein binding; GO:0005488 binding; "]
["Q7Z7H5","Transmembrane emp24 domain-containing protein 4 OS=Homo sapiens OX=9606 GN=TMED4","TMED4",25.943,13.367,16.3,3,4,3,1.1,1.007,1.166,0.974,0.837,0.935,0.839,0.0475,"extracellular\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0023056 positive regulation of signaling; GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling; GO:0010647 positive regulation of cell communication; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:0051716 cellular response to stimulus; GO:1902531 regulation of intracellular signal transduction; GO:0048522 positive regulation of cellular process; GO:0071702 organic substance transport; GO:0023052 signaling; GO:0048518 positive regulation of biological process; GO:0006810 transport; GO:0045184 establishment of protein localization; GO:0050789 regulation of biological process; GO:0048583 regulation of response to stimulus; GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling; GO:0009967 positive regulation of signal transduction; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0044421 extracellular region part; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0044432 endoplasmic reticulum part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0004871 signal transducer activity; ","K20346",null,null,"IPR009038; ","GOLD domain; \r"]
["Q86SQ9","Dehydrodolichyl diphosphate synthase complex subunit DHDDS OS=Homo sapiens OX=9606 GN=DHDDS","DHDDS",38.657,2.6788,3.3,1,1,1,1.083,1.491,1.161,0.703,0.666,0.937,0.617,0.0281,"cytoplasm\r","GO:0043413 macromolecule glycosylation; GO:1901615 organic hydroxy compound metabolic process; GO:0006066 alcohol metabolic process; GO:0008654 phospholipid biosynthetic process; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0009058 biosynthetic process; GO:0006489 dolichyl diphosphate biosynthetic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0008610 lipid biosynthetic process; GO:0071704 organic substance metabolic process; GO:0008299 isoprenoid biosynthetic process; GO:0008152 metabolic process; GO:0046465 dolichyl diphosphate metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:1901135 carbohydrate derivative metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0070085 glycosylation; GO:0006629 lipid metabolic process; GO:0006486 protein glycosylation; GO:0006720 isoprenoid metabolic process; GO:0009101 glycoprotein biosynthetic process; GO:0044711 single-organism biosynthetic process; GO:0006488 dolichol-linked oligosaccharide biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0046165 alcohol biosynthetic process; GO:0009100 glycoprotein metabolic process; GO:1901617 organic hydroxy compound biosynthetic process; GO:0044238 primary metabolic process; GO:0016094 polyprenol biosynthetic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0016093 polyprenol metabolic process; GO:0090407 organophosphate biosynthetic process; GO:0006490 oligosaccharide-lipid intermediate biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0044283 small molecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0019637 organophosphate metabolic process; GO:0006464 cellular protein modification process; GO:0006644 phospholipid metabolic process; GO:0036211 protein modification process; GO:0043412 macromolecule modification; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044432 endoplasmic reticulum part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; ","GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups; GO:0005515 protein binding; GO:0003824 catalytic activity; GO:0016740 transferase activity; GO:0005488 binding; ","K11778","DHDDS; ditrans,polycis-polyprenyl diphosphate synthase [EC:2.5.1.87]","hsa00900 Terpenoid backbone biosynthesis - Homo sapiens (human); "]
["Q86T13","C-type lectin domain family 14 member A OS=Homo sapiens OX=9606 GN=CLEC14A","CLEC14A",51.635,12.056,5.7,2,2,2,1.104,1.023,1.071,0.928,0.942,0.948,0.881,0.00542,"extracellular\r",null,"GO:0016020 membrane; GO:0044421 extracellular region part; GO:0009897 external side of plasma membrane; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0031012 extracellular matrix; GO:0044459 plasma membrane part; GO:0044464 cell part; GO:0044425 membrane part; GO:1903561 extracellular vesicle; GO:0009986 cell surface; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0098552 side of membrane; ","GO:0030246 carbohydrate binding; GO:1990430 extracellular matrix protein binding; GO:0005515 protein binding; GO:0005488 binding; ","K17528",null,null,"IPR001304; IPR016187; IPR016186; ","C-type lectin-like; C-type lectin fold; C-type lectin-like/link domain; \r"]
["Q86TD4","Sarcalumenin OS=Homo sapiens OX=9606 GN=SRL","SRL",100.79,9.0203,1.3,1,2,1,0.276,0.212,1.363,1.362,1.409,1.307,2.203,0.187,"extracellular\r",null,"GO:0005788 endoplasmic reticulum lumen; GO:0043229 intracellular organelle; GO:0005783 endoplasmic reticulum; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0016529 sarcoplasmic reticulum; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0033018 sarcoplasmic reticulum lumen; GO:0005623 cell; GO:0016528 sarcoplasm; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0070013 intracellular organelle lumen; GO:0044432 endoplasmic reticulum part; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0032561 guanyl ribonucleotide binding; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ",{"$nulls":3},"IPR030381; IPR027417; IPR031692; ","\"Dynamin-type guanine nucleotide-binding (G) domain; P-loop containing nucleoside triphosphate hydrolase; EH domain-containing protein, N-terminal; \"\r"]
["Q86U38","Nucleolar protein 9 OS=Homo sapiens OX=9606 GN=NOP9","NOP9",69.437,10.983,5.8,3,6,3,1.028,0.996,0.927,1.114,0.95,0.997,1.037,0.564,"nucleus\r",null,null,"GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; ","K14790",null,null,"IPR011989; IPR016024; ","Armadillo-like helical; Armadillo-type fold; \r"]
["Q86U42","Polyadenylate-binding protein 2 OS=Homo sapiens OX=9606 GN=PABPN1","PABPN1",32.749,14.588,11.8,5,8,5,0.929,0.986,0.951,1.096,1.022,1.003,1.089,0.0573,"nucleus\r","GO:0044700 single organism signaling; GO:0050658 RNA transport; GO:0065008 regulation of biological quality; GO:1904245 regulation of polynucleotide adenylyltransferase activity; GO:0097659 nucleic acid-templated transcription; GO:1904247 positive regulation of polynucleotide adenylyltransferase activity; GO:0051169 nuclear transport; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0009607 response to biotic stimulus; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0015931 nucleobase-containing compound transport; GO:0044093 positive regulation of molecular function; GO:0044003 modification by symbiont of host morphology or physiology; GO:0019538 protein metabolic process; GO:0051347 positive regulation of transferase activity; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0008104 protein localization; GO:0006396 RNA processing; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0050684 regulation of mRNA processing; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0006611 protein export from nucleus; GO:0071396 cellular response to lipid; GO:0051704 multi-organism process; GO:0006810 transport; GO:0000165 MAPK cascade; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0006913 nucleocytoplasmic transport; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0050794 regulation of cellular process; GO:0016310 phosphorylation; GO:0046907 intracellular transport; GO:0051028 mRNA transport; GO:0044267 cellular protein metabolic process; GO:1901700 response to oxygen-containing compound; GO:0016973 poly(A)+ mRNA export from nucleus; GO:0051236 establishment of RNA localization; GO:0051817 modification of morphology or physiology of other organism involved in symbiotic interaction; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034613 cellular protein localization; GO:0008380 RNA splicing; GO:0009617 response to bacterium; GO:0023014 signal transduction by protein phosphorylation; GO:0032496 response to lipopolysaccharide; GO:0006403 RNA localization; GO:0006405 RNA export from nucleus; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0071702 organic substance transport; GO:0046778 modification by virus of host mRNA processing; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0045184 establishment of protein localization; GO:1903311 regulation of mRNA metabolic process; GO:0006793 phosphorus metabolic process; GO:0071219 cellular response to molecule of bacterial origin; GO:0043412 macromolecule modification; GO:0051179 localization; GO:0003012 muscle system process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0051168 nuclear export; GO:0044764 multi-organism cellular process; GO:0035821 modification of morphology or physiology of other organism; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0044068 modulation by symbiont of host cellular process; GO:0006353 DNA-templated transcription, termination; GO:0007165 signal transduction; GO:0071427 mRNA-containing ribonucleoprotein complex export from nucleus; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0050657 nucleic acid transport; GO:0033036 macromolecule localization; GO:0070887 cellular response to chemical stimulus; GO:0010468 regulation of gene expression; GO:0002237 response to molecule of bacterial origin; GO:1901360 organic cyclic compound metabolic process; GO:0023052 signaling; GO:0071166 ribonucleoprotein complex localization; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0019054 modulation by virus of host process; GO:0036211 protein modification process; GO:0031123 RNA 3'-end processing; GO:0071222 cellular response to lipopolysaccharide; GO:0006725 cellular aromatic compound metabolic process; GO:0031124 mRNA 3'-end processing; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0071704 organic substance metabolic process; GO:0033993 response to lipid; GO:0000398 mRNA splicing, via spliceosome; GO:0006936 muscle contraction; GO:0006468 protein phosphorylation; GO:0071216 cellular response to biotic stimulus; GO:0016032 viral process; GO:0006886 intracellular protein transport; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006406 mRNA export from nucleus; GO:0003008 system process; GO:0035556 intracellular signal transduction; GO:0006369 termination of RNA polymerase II transcription; GO:0006807 nitrogen compound metabolic process; GO:0051701 interaction with host; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0043085 positive regulation of catalytic activity; GO:0070727 cellular macromolecule localization; GO:1901701 cellular response to oxygen-containing compound; GO:0039656 modulation by virus of host gene expression; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0071426 ribonucleoprotein complex export from nucleus; GO:0006366 transcription from RNA polymerase II promoter; GO:0010467 gene expression; GO:0019048 modulation by virus of host morphology or physiology; GO:0071705 nitrogen compound transport; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0005737 cytoplasm; GO:0042405 nuclear inclusion body; GO:0016234 inclusion body; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0005622 intracellular; GO:0044464 cell part; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:1901265 nucleoside phosphate binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0070063 RNA polymerase binding; GO:0019899 enzyme binding; GO:0036094 small molecule binding; ","K14396","PABPN1; polyadenylate-binding protein 2","hsa03015 mRNA surveillance pathway - Homo sapiens (human); hsa05164 Influenza A - Homo sapiens (human); ","IPR000504; IPR012677; ","RNA recognition motif domain; Nucleotide-binding alpha-beta plait domain; \r"]
["Q86UP2","Kinectin OS=Homo sapiens OX=9606 GN=KTN1","KTN1",156.27,244.05,31,44,57,44,1.013,0.988,0.979,0.998,1.024,0.966,1.003,0.905,"endoplasmic reticulum\r","GO:0044763 single-organism cellular process; GO:0007018 microtubule-based movement; GO:0006928 movement of cell or subcellular component; GO:0044699 single-organism process; GO:0009987 cellular process; GO:0007017 microtubule-based process; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0031226 intrinsic component of plasma membrane; GO:0005783 endoplasmic reticulum; GO:0071944 cell periphery; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0044432 endoplasmic reticulum part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0050839 cell adhesion molecule binding; GO:0003723 RNA binding; GO:0008092 cytoskeletal protein binding; GO:0019894 kinesin binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; ","K17975"]
["Q86UX2","Inter-alpha-trypsin inhibitor heavy chain H5 OS=Homo sapiens OX=9606 GN=ITIH5","ITIH5",104.58,22.771,5.2,4,6,4,1.231,0.96,1.025,1.013,0.883,0.91,0.873,0.195,"plasma membrane\r","GO:0050794 regulation of cellular process; GO:0010951 negative regulation of endopeptidase activity; GO:0060255 regulation of macromolecule metabolic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0051346 negative regulation of hydrolase activity; GO:0030203 glycosaminoglycan metabolic process; GO:0071704 organic substance metabolic process; GO:0010466 negative regulation of peptidase activity; GO:0008152 metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0043170 macromolecule metabolic process; GO:0006022 aminoglycan metabolic process; GO:0030212 hyaluronan metabolic process; GO:0052548 regulation of endopeptidase activity; GO:0045861 negative regulation of proteolysis; GO:1903510 mucopolysaccharide metabolic process; GO:0080090 regulation of primary metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0030162 regulation of proteolysis; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0009892 negative regulation of metabolic process; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0051246 regulation of protein metabolic process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0065009 regulation of molecular function; GO:0051248 negative regulation of protein metabolic process; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0052547 regulation of peptidase activity; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0005576 extracellular region; ","GO:0004867 serine-type endopeptidase inhibitor activity; GO:0030234 enzyme regulator activity; GO:0030414 peptidase inhibitor activity; GO:0061134 peptidase regulator activity; GO:0061135 endopeptidase regulator activity; GO:0098772 molecular function regulator; GO:0004857 enzyme inhibitor activity; GO:0004866 endopeptidase inhibitor activity; ",{"$nulls":3},"IPR010600; IPR013694; IPR002035; ","\"Inter-alpha-trypsin inhibitor heavy chain, C-terminal; VIT domain; von Willebrand factor, type A; \"\r"]
["Q86V81","THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF","ALYREF",26.888,31.921,12.8,3,5,3,0.991,0.993,0.995,1.053,1.008,1.002,1.028,0.221,"cytoplasm\r","GO:0050658 RNA transport; GO:0001649 osteoblast differentiation; GO:0097659 nucleic acid-templated transcription; GO:0009891 positive regulation of biosynthetic process; GO:0051169 nuclear transport; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:1902583 multi-organism intracellular transport; GO:0008152 metabolic process; GO:0015931 nucleobase-containing compound transport; GO:0032784 regulation of DNA-templated transcription, elongation; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0075733 intracellular transport of virus; GO:0008104 protein localization; GO:0000018 regulation of DNA recombination; GO:0006396 RNA processing; GO:0018130 heterocycle biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0001503 ossification; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044763 single-organism cellular process; GO:0032786 positive regulation of DNA-templated transcription, elongation; GO:0032774 RNA biosynthetic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0006611 protein export from nucleus; GO:0051704 multi-organism process; GO:0006810 transport; GO:1903506 regulation of nucleic acid-templated transcription; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006913 nucleocytoplasmic transport; GO:0031297 replication fork processing; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0044707 single-multicellular organism process; GO:0006260 DNA replication; GO:0006259 DNA metabolic process; GO:0051028 mRNA transport; GO:0051236 establishment of RNA localization; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0000375 RNA splicing, via transesterification reactions; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0034613 cellular protein localization; GO:0008380 RNA splicing; GO:0051254 positive regulation of RNA metabolic process; GO:0046794 transport of virus; GO:0006403 RNA localization; GO:0006405 RNA export from nucleus; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0045184 establishment of protein localization; GO:0044766 multi-organism transport; GO:0031325 positive regulation of cellular metabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0051179 localization; GO:0048869 cellular developmental process; GO:0045005 DNA-dependent DNA replication maintenance of fidelity; GO:0044699 single-organism process; GO:0051168 nuclear export; GO:1902581 multi-organism cellular localization; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0051234 establishment of localization; GO:0006353 DNA-templated transcription, termination; GO:2001141 regulation of RNA biosynthetic process; GO:0071427 mRNA-containing ribonucleoprotein complex export from nucleus; GO:0051649 establishment of localization in cell; GO:0050657 nucleic acid transport; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0006261 DNA-dependent DNA replication; GO:0033036 macromolecule localization; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0046784 viral mRNA export from host cell nucleus; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0071166 ribonucleoprotein complex localization; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:0050789 regulation of biological process; GO:0051052 regulation of DNA metabolic process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0019222 regulation of metabolic process; GO:0031123 RNA 3'-end processing; GO:1902579 multi-organism localization; GO:0006725 cellular aromatic compound metabolic process; GO:0031124 mRNA 3'-end processing; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0000398 mRNA splicing, via spliceosome; GO:0016032 viral process; GO:0006886 intracellular protein transport; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006406 mRNA export from nucleus; GO:0006355 regulation of transcription, DNA-templated; GO:0006369 termination of RNA polymerase II transcription; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0070727 cellular macromolecule localization; GO:0071426 ribonucleoprotein complex export from nucleus; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044767 single-organism developmental process; GO:0006366 transcription from RNA polymerase II promoter; GO:0010467 gene expression; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0071705 nitrogen compound transport; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005681 spliceosomal complex; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0000346 transcription export complex; GO:0071013 catalytic step 2 spliceosome; GO:1990904 ribonucleoprotein complex; GO:0043234 protein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:1901265 nucleoside phosphate binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0036094 small molecule binding; ","K12881","THOC4; THO complex subunit 4","hsa03040 Spliceosome - Homo sapiens (human); hsa03015 mRNA surveillance pathway - Homo sapiens (human); hsa05168 Herpes simplex infection - Homo sapiens (human); hsa03013 RNA transport - Homo sapiens (human); ","IPR000504; IPR012677; IPR025715; ","\"RNA recognition motif domain; Nucleotide-binding alpha-beta plait domain; Chromatin target of PRMT1 protein, C-terminal; \"\r"]
["Q86VN1","Vacuolar protein-sorting-associated protein 36 OS=Homo sapiens OX=9606 GN=VPS36","VPS36",43.816,12.676,14.2,5,6,5,0.889,0.988,0.932,1.016,1.026,1.148,1.136,0.0635,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0010256 endomembrane system organization; GO:0072594 establishment of protein localization to organelle; GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; GO:0097659 nucleic acid-templated transcription; GO:0009058 biosynthetic process; GO:0006623 protein targeting to vacuole; GO:0006914 autophagy; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0022607 cellular component assembly; GO:0072666 establishment of protein localization to vacuole; GO:0036258 multivesicular body assembly; GO:0033365 protein localization to organelle; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0016236 macroautophagy; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0036257 multivesicular body organization; GO:0032774 RNA biosynthetic process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0031323 regulation of cellular metabolic process; GO:0016070 RNA metabolic process; GO:0016197 endosomal transport; GO:0072665 protein localization to vacuole; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0030163 protein catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0032509 endosome transport via multivesicular body sorting pathway; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:0070925 organelle assembly; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0045324 late endosome to vacuole transport; GO:0006886 intracellular protein transport; GO:0051171 regulation of nitrogen compound metabolic process; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0006508 proteolysis; GO:0009059 macromolecule biosynthetic process; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; GO:0043632 modification-dependent macromolecule catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0019941 modification-dependent protein catabolic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0016050 vesicle organization; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006996 organelle organization; GO:0007034 vacuolar transport; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0051179 localization; GO:0007032 endosome organization; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0036452 ESCRT complex; GO:0044425 membrane part; GO:0031902 late endosome membrane; GO:0044464 cell part; GO:0005622 intracellular; GO:0005764 lysosome; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0000814 ESCRT II complex; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0010008 endosome membrane; GO:0005770 late endosome; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005773 vacuole; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901981 phosphatidylinositol phosphate binding; GO:0032266 phosphatidylinositol-3-phosphate binding; GO:0005488 binding; GO:0005543 phospholipid binding; GO:0035091 phosphatidylinositol binding; GO:0043167 ion binding; GO:0008289 lipid binding; GO:0043130 ubiquitin binding; GO:0008022 protein C-terminus binding; GO:0043168 anion binding; GO:0005515 protein binding; GO:0032182 ubiquitin-like protein binding; ","K12190","VPS36; ESCRT-II complex subunit VPS36","hsa04144 Endocytosis - Homo sapiens (human); ","IPR011991; IPR011993; IPR021648; ","\"Winged helix-turn-helix DNA-binding domain; PH domain-like; Vacuolar protein sorting protein 36, GLUE domain; \"\r"]
["Q86VS8","Protein Hook homolog 3 OS=Homo sapiens OX=9606 GN=HOOK3","HOOK3",83.125,10.92,6.5,5,5,5,1.015,0.924,1.084,0.865,1.049,1.063,0.985,0.84,"nucleus\r","GO:0051093 negative regulation of developmental process; GO:0010256 endomembrane system organization; GO:0034453 microtubule anchoring; GO:0007420 brain development; GO:0048869 cellular developmental process; GO:0051647 nucleus localization; GO:1905508 protein localization to microtubule organizing center; GO:0022008 neurogenesis; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0098927 vesicle-mediated transport between endosomal compartments; GO:0061351 neural precursor cell proliferation; GO:0051649 establishment of localization in cell; GO:0060322 head development; GO:0033365 protein localization to organelle; GO:0007033 vacuole organization; GO:0045596 negative regulation of cell differentiation; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0008333 endosome to lysosome transport; GO:0032501 multicellular organismal process; GO:0007040 lysosome organization; GO:0050768 negative regulation of neurogenesis; GO:0006810 transport; GO:0016197 endosomal transport; GO:1902589 single-organism organelle organization; GO:0000226 microtubule cytoskeleton organization; GO:0048513 animal organ development; GO:0044380 protein localization to cytoskeleton; GO:0072698 protein localization to microtubule cytoskeleton; GO:0050789 regulation of biological process; GO:0072393 microtubule anchoring at microtubule organizing center; GO:0007417 central nervous system development; GO:0021846 cell proliferation in forebrain; GO:0098727 maintenance of cell number; GO:0051645 Golgi localization; GO:0071539 protein localization to centrosome; GO:0010721 negative regulation of cell development; GO:0048856 anatomical structure development; GO:0097435 supramolecular fiber organization; GO:2000026 regulation of multicellular organismal development; GO:0051640 organelle localization; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0030705 cytoskeleton-dependent intracellular transport; GO:0051239 regulation of multicellular organismal process; GO:0030154 cell differentiation; GO:0051961 negative regulation of nervous system development; GO:0030900 forebrain development; GO:0019827 stem cell population maintenance; GO:0034454 microtubule anchoring at centrosome; GO:0007275 multicellular organism development; GO:0034613 cellular protein localization; GO:0016482 cytosolic transport; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0097150 neuronal stem cell population maintenance; GO:0045595 regulation of cell differentiation; GO:0007041 lysosomal transport; GO:0045022 early endosome to late endosome transport; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0016050 vesicle organization; GO:0008283 cell proliferation; GO:0071702 organic substance transport; GO:0007017 microtubule-based process; GO:0031122 cytoplasmic microtubule organization; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0006996 organelle organization; GO:0007034 vacuolar transport; GO:0044767 single-organism developmental process; GO:0080171 lytic vacuole organization; GO:0051179 localization; GO:0007032 endosome organization; GO:0050793 regulation of developmental process; GO:0022027 interkinetic nuclear migration; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; GO:0050767 regulation of neurogenesis; ","GO:0044450 microtubule organizing center part; GO:0005874 microtubule; GO:0005801 cis-Golgi network; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0000242 pericentriolar material; GO:0005623 cell; GO:0099080 supramolecular complex; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0005815 microtubule organizing center; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0034451 centriolar satellite; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0099081 supramolecular polymer; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005813 centrosome; GO:0070695 FHF complex; GO:0005794 Golgi apparatus; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0051959 dynein light intermediate chain binding; GO:0008092 cytoskeletal protein binding; GO:0042802 identical protein binding; GO:0008017 microtubule binding; GO:0005488 binding; GO:0015631 tubulin binding; GO:0005515 protein binding; ","K16536"]
["Q86W92","Liprin-beta-1 OS=Homo sapiens OX=9606 GN=PPFIBP1","PPFIBP1",114.02,25.575,6.8,6,8,5,1.01,1.043,1.071,0.949,0.982,1.016,0.943,0.0878,"nucleus\r","GO:0007155 cell adhesion; GO:0022610 biological adhesion; ","GO:0016020 membrane; GO:0005925 focal adhesion; GO:0044464 cell part; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0005912 adherens junction; GO:0070161 anchoring junction; GO:0030055 cell-substrate junction; GO:0005623 cell; GO:0005886 plasma membrane; GO:0005924 cell-substrate adherens junction; ","GO:0050839 cell adhesion molecule binding; GO:0005515 protein binding; GO:0005488 binding; GO:0045296 cadherin binding; ",{"$nulls":3},"IPR013761; IPR001660; ","Sterile alpha motif/pointed domain; Sterile alpha motif domain; \r"]
["Q86WR0","Coiled-coil domain-containing protein 25 OS=Homo sapiens OX=9606 GN=CCDC25","CCDC25",24.479,6.4538,11.5,2,2,2,0.891,1.05,0.897,1.042,0.987,1.136,1.115,0.178,"nucleus\r",null,"GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR008532; ","Domain of unknown function DUF814; \r"]
["Q86WV6","Stimulator of interferon genes protein OS=Homo sapiens OX=9606 GN=TMEM173","TMEM173",42.192,20.163,5.5,1,1,1,0.976,1.026,1.005,0.92,1.023,1.055,0.997,0.924,"plasma membrane\r","GO:0032481 positive regulation of type I interferon production; GO:0045321 leukocyte activation; GO:1903533 regulation of protein targeting; GO:0098542 defense response to other organism; GO:0009891 positive regulation of biosynthetic process; GO:0031347 regulation of defense response; GO:0071345 cellular response to cytokine stimulus; GO:0009607 response to biotic stimulus; GO:0009605 response to external stimulus; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0044419 interspecies interaction between organisms; GO:0051099 positive regulation of binding; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0006810 transport; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051223 regulation of protein transport; GO:0002682 regulation of immune system process; GO:0042307 positive regulation of protein import into nucleus; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0035456 response to interferon-beta; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0032606 type I interferon production; GO:0002283 neutrophil activation involved in immune response; GO:0001819 positive regulation of cytokine production; GO:0033158 regulation of protein import into nucleus, translocation; GO:0080134 regulation of response to stress; GO:0051239 regulation of multicellular organismal process; GO:0060341 regulation of cellular localization; GO:0042990 regulation of transcription factor import into nucleus; GO:0050688 regulation of defense response to virus; GO:0031349 positive regulation of defense response; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0032880 regulation of protein localization; GO:0050778 positive regulation of immune response; GO:0071359 cellular response to dsRNA; GO:0002253 activation of immune response; GO:0051254 positive regulation of RNA metabolic process; GO:0006950 response to stress; GO:0043900 regulation of multi-organism process; GO:0016192 vesicle-mediated transport; GO:0032101 regulation of response to external stimulus; GO:0071407 cellular response to organic cyclic compound; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0002263 cell activation involved in immune response; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:1900182 positive regulation of protein localization to nucleus; GO:0045055 regulated exocytosis; GO:0033160 positive regulation of protein import into nucleus, translocation; GO:0046822 regulation of nucleocytoplasmic transport; GO:1904951 positive regulation of establishment of protein localization; GO:0001816 cytokine production; GO:0031325 positive regulation of cellular metabolic process; GO:0001775 cell activation; GO:0012501 programmed cell death; GO:0051179 localization; GO:0031328 positive regulation of cellular biosynthetic process; GO:0048584 positive regulation of response to stimulus; GO:0006955 immune response; GO:0002230 positive regulation of defense response to virus by host; GO:1903827 regulation of cellular protein localization; GO:1904591 positive regulation of protein import; GO:0006887 exocytosis; GO:0032092 positive regulation of protein binding; GO:0044699 single-organism process; GO:0035458 cellular response to interferon-beta; GO:0044764 multi-organism cellular process; GO:0051234 establishment of localization; GO:2001141 regulation of RNA biosynthetic process; GO:0042306 regulation of protein import into nucleus; GO:0045088 regulation of innate immune response; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0006915 apoptotic process; GO:0046824 positive regulation of nucleocytoplasmic transport; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0050691 regulation of defense response to virus by host; GO:0002697 regulation of immune effector process; GO:0070887 cellular response to chemical stimulus; GO:0002274 myeloid leukocyte activation; GO:0010468 regulation of gene expression; GO:0034097 response to cytokine; GO:0031326 regulation of cellular biosynthetic process; GO:0002446 neutrophil mediated immunity; GO:0051098 regulation of binding; GO:0043331 response to dsRNA; GO:0048522 positive regulation of cellular process; GO:0032386 regulation of intracellular transport; GO:0002444 myeloid leukocyte mediated immunity; GO:0051050 positive regulation of transport; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0051607 defense response to virus; GO:1901699 cellular response to nitrogen compound; GO:0032940 secretion by cell; GO:1900180 regulation of protein localization to nucleus; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0043299 leukocyte degranulation; GO:0006952 defense response; GO:0009615 response to virus; GO:0051222 positive regulation of protein transport; GO:0002218 activation of innate immune response; GO:0032479 regulation of type I interferon production; GO:0002831 regulation of response to biotic stimulus; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0090316 positive regulation of intracellular protein transport; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:1903829 positive regulation of cellular protein localization; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0071310 cellular response to organic substance; GO:0043207 response to external biotic stimulus; GO:1904589 regulation of protein import; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0045087 innate immune response; GO:0070201 regulation of establishment of protein localization; GO:0043393 regulation of protein binding; GO:0016032 viral process; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0033157 regulation of intracellular protein transport; GO:0042993 positive regulation of transcription factor import into nucleus; GO:0006355 regulation of transcription, DNA-templated; GO:0045089 positive regulation of innate immune response; GO:0043330 response to exogenous dsRNA; GO:0032388 positive regulation of intracellular transport; GO:0051049 regulation of transport; GO:0050792 regulation of viral process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0071360 cellular response to exogenous dsRNA; GO:0008219 cell death; GO:0002684 positive regulation of immune system process; GO:0001817 regulation of cytokine production; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0032608 interferon-beta production; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0019867 outer membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0042579 microbody; GO:0098805 whole membrane; GO:0048471 perinuclear region of cytoplasm; GO:0031968 organelle outer membrane; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0044429 mitochondrial part; GO:0005777 peroxisome; GO:0005741 mitochondrial outer membrane; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0016021 integral component of membrane; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0030667 secretory granule membrane; GO:0005634 nucleus; GO:0044432 endoplasmic reticulum part; GO:0031975 envelope; GO:0005794 Golgi apparatus; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0030551 cyclic nucleotide binding; GO:1901265 nucleoside phosphate binding; GO:0031625 ubiquitin protein ligase binding; GO:0061507 cyclic-GMP-AMP binding; GO:0046983 protein dimerization activity; GO:0043167 ion binding; GO:0019901 protein kinase binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0019900 kinase binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0097367 carbohydrate derivative binding; GO:0042802 identical protein binding; GO:0035438 cyclic-di-GMP binding; GO:0032553 ribonucleotide binding; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032561 guanyl ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0019001 guanyl nucleotide binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0008134 transcription factor binding; GO:0019899 enzyme binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; ","K12654","TMEM173; transmembrane protein 173","hsa04623 Cytosolic DNA-sensing pathway - Homo sapiens (human); hsa04622 RIG-I-like receptor signaling pathway - Homo sapiens (human); hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human); ","IPR033952; ","\"Stimulator of interferon genes protein, C-terminal; \"\r"]
["Q86X55","Histone-arginine methyltransferase CARM1 OS=Homo sapiens OX=9606 GN=CARM1","CARM1",65.853,12.422,5.1,3,6,3,0.939,1.078,1.05,1.032,0.926,1.012,0.968,0.591,"nucleus\r","GO:0044700 single organism signaling; GO:1902807 negative regulation of cell cycle G1/S phase transition; GO:0035247 peptidyl-arginine omega-N-methylation; GO:2000171 negative regulation of dendrite development; GO:0009891 positive regulation of biosynthetic process; GO:0046683 response to organophosphorus; GO:0044255 cellular lipid metabolic process; GO:0032091 negative regulation of protein binding; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0072431 signal transduction involved in mitotic G1 DNA damage checkpoint; GO:1902403 signal transduction involved in mitotic DNA integrity checkpoint; GO:0008152 metabolic process; GO:0044093 positive regulation of molecular function; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0030522 intracellular receptor signaling pathway; GO:0090068 positive regulation of cell cycle process; GO:0030518 intracellular steroid hormone receptor signaling pathway; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0044773 mitotic DNA damage checkpoint; GO:0060350 endochondral bone morphogenesis; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:2000134 negative regulation of G1/S transition of mitotic cell cycle; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0051704 multi-organism process; GO:0071396 cellular response to lipid; GO:0010243 response to organonitrogen compound; GO:0051092 positive regulation of NF-kappaB transcription factor activity; GO:0051591 response to cAMP; GO:1902400 intracellular signal transduction involved in G1 DNA damage checkpoint; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0045665 negative regulation of neuron differentiation; GO:0044260 cellular macromolecule metabolic process; GO:0010721 negative regulation of cell development; GO:0010975 regulation of neuron projection development; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0044707 single-multicellular organism process; GO:0016570 histone modification; GO:0018216 peptidyl-arginine methylation; GO:1901700 response to oxygen-containing compound; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0009653 anatomical structure morphogenesis; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1902402 signal transduction involved in mitotic DNA damage checkpoint; GO:0009889 regulation of biosynthetic process; GO:0044819 mitotic G1/S transition checkpoint; GO:0031345 negative regulation of cell projection organization; GO:1902680 positive regulation of RNA biosynthetic process; GO:0034613 cellular protein localization; GO:0006950 response to stress; GO:0072331 signal transduction by p53 class mediator; GO:0051960 regulation of nervous system development; GO:0060284 regulation of cell development; GO:0010977 negative regulation of neuron projection development; GO:0010033 response to organic substance; GO:1901576 organic substance biosynthetic process; GO:0006974 cellular response to DNA damage stimulus; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0060348 bone development; GO:0034971 histone H3-R17 methylation; GO:0006996 organelle organization; GO:0043414 macromolecule methylation; GO:0031325 positive regulation of cellular metabolic process; GO:0043412 macromolecule modification; GO:0008284 positive regulation of cell proliferation; GO:2000045 regulation of G1/S transition of mitotic cell cycle; GO:0051093 negative regulation of developmental process; GO:0023051 regulation of signaling; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0071383 cellular response to steroid hormone stimulus; GO:0032259 methylation; GO:0030520 intracellular estrogen receptor signaling pathway; GO:2001141 regulation of RNA biosynthetic process; GO:0045930 negative regulation of mitotic cell cycle; GO:0007165 signal transduction; GO:0000077 DNA damage checkpoint; GO:0035246 peptidyl-arginine N-methylation; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:1902806 regulation of cell cycle G1/S phase transition; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0033036 macromolecule localization; GO:0051726 regulation of cell cycle; GO:0006629 lipid metabolic process; GO:0031571 mitotic G1 DNA damage checkpoint; GO:0031326 regulation of cellular biosynthetic process; GO:0051098 regulation of binding; GO:0023052 signaling; GO:0006351 transcription, DNA-templated; GO:0045664 regulation of neuron differentiation; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0003420 regulation of growth plate cartilage chondrocyte proliferation; GO:0006325 chromatin organization; GO:0036211 protein modification process; GO:0072401 signal transduction involved in DNA integrity checkpoint; GO:0016571 histone methylation; GO:0016043 cellular component organization; GO:0045786 negative regulation of cell cycle; GO:0072395 signal transduction involved in cell cycle checkpoint; GO:0040008 regulation of growth; GO:1901988 negative regulation of cell cycle phase transition; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0048638 regulation of developmental growth; GO:0071704 organic substance metabolic process; GO:0033993 response to lipid; GO:0030154 cell differentiation; GO:0060349 bone morphogenesis; GO:2000027 regulation of organ morphogenesis; GO:0051961 negative regulation of nervous system development; GO:0016032 viral process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0045595 regulation of cell differentiation; GO:0006355 regulation of transcription, DNA-templated; GO:0072422 signal transduction involved in DNA damage checkpoint; GO:0035556 intracellular signal transduction; GO:0044249 cellular biosynthetic process; GO:0009755 hormone-mediated signaling pathway; GO:0018193 peptidyl-amino acid modification; GO:0045598 regulation of fat cell differentiation; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0033146 regulation of intracellular estrogen receptor signaling pathway; GO:0071495 cellular response to endogenous stimulus; GO:0071158 positive regulation of cell cycle arrest; GO:0010467 gene expression; GO:0022402 cell cycle process; GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; GO:0043401 steroid hormone mediated signaling pathway; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0050767 regulation of neurogenesis; GO:0097659 nucleic acid-templated transcription; GO:0008213 protein alkylation; GO:1903010 regulation of bone development; GO:0048545 response to steroid hormone; GO:0009719 response to endogenous stimulus; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0033365 protein localization to organelle; GO:0044419 interspecies interaction between organisms; GO:0008104 protein localization; GO:0007399 nervous system development; GO:0014070 response to organic cyclic compound; GO:0018130 heterocycle biosynthetic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0050768 negative regulation of neurogenesis; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0072413 signal transduction involved in mitotic cell cycle checkpoint; GO:0010948 negative regulation of cell cycle process; GO:0044710 single-organism metabolic process; GO:0051090 regulation of sequence-specific DNA binding transcription factor activity; GO:0010604 positive regulation of macromolecule metabolic process; GO:0009887 animal organ morphogenesis; GO:0006464 cellular protein modification process; GO:0034969 histone arginine methylation; GO:0051094 positive regulation of developmental process; GO:1901362 organic cyclic compound biosynthetic process; GO:0050794 regulation of cellular process; GO:0034502 protein localization to chromosome; GO:0033554 cellular response to stress; GO:0007346 regulation of mitotic cell cycle; GO:0034970 histone H3-R2 methylation; GO:0042127 regulation of cell proliferation; GO:0044267 cellular protein metabolic process; GO:0048523 negative regulation of cellular process; GO:0051239 regulation of multicellular organismal process; GO:0045597 positive regulation of cell differentiation; GO:0030330 DNA damage response, signal transduction by p53 class mediator; GO:0006479 protein methylation; GO:0019438 aromatic compound biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0014074 response to purine-containing compound; GO:1901987 regulation of cell cycle phase transition; GO:0007093 mitotic cell cycle checkpoint; GO:0051171 regulation of nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0016569 covalent chromatin modification; GO:0009966 regulation of signal transduction; GO:0061035 regulation of cartilage development; GO:0045787 positive regulation of cell cycle; GO:0051254 positive regulation of RNA metabolic process; GO:0048731 system development; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0071407 cellular response to organic cyclic compound; GO:0044238 primary metabolic process; GO:0048705 skeletal system morphogenesis; GO:0071168 protein localization to chromatin; GO:0051276 chromosome organization; GO:0031328 positive regulation of cellular biosynthetic process; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0046620 regulation of organ growth; GO:0051129 negative regulation of cellular component organization; GO:0044783 G1 DNA damage checkpoint; GO:0022008 neurogenesis; GO:0051241 negative regulation of multicellular organismal process; GO:0044764 multi-organism cellular process; GO:0018195 peptidyl-arginine modification; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0044774 mitotic DNA integrity checkpoint; GO:1901991 negative regulation of mitotic cell cycle phase transition; GO:0000075 cell cycle checkpoint; GO:0045596 negative regulation of cell differentiation; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0031570 DNA integrity checkpoint; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity; GO:1902415 regulation of mRNA binding; GO:0016070 RNA metabolic process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0051100 negative regulation of binding; GO:0032870 cellular response to hormone stimulus; GO:0007568 aging; GO:0019222 regulation of metabolic process; GO:0033143 regulation of intracellular steroid hormone receptor signaling pathway; GO:0048856 anatomical structure development; GO:1905214 regulation of RNA binding; GO:0001501 skeletal system development; GO:2000026 regulation of multicellular organismal development; GO:0006725 cellular aromatic compound metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031344 regulation of cell projection organization; GO:0050896 response to stimulus; GO:0043393 regulation of protein binding; GO:0045600 positive regulation of fat cell differentiation; GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine; GO:0042770 signal transduction in response to DNA damage; GO:0009987 cellular process; GO:0071156 regulation of cell cycle arrest; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0051641 cellular localization; GO:0070727 cellular macromolecule localization; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0050773 regulation of dendrite development; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0051128 regulation of cellular component organization; GO:0009725 response to hormone; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0044798 nuclear transcription factor complex; GO:0005667 transcription factor complex; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0090575 RNA polymerase II transcription factor complex; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity; GO:0008757 S-adenosylmethionine-dependent methyltransferase activity; GO:0008168 methyltransferase activity; GO:0016274 protein-arginine N-methyltransferase activity; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:0097159 organic cyclic compound binding; GO:0000975 regulatory region DNA binding; GO:1901363 heterocyclic compound binding; GO:0042802 identical protein binding; GO:0001105 RNA polymerase II transcription coactivator activity; GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity; GO:0008276 protein methyltransferase activity; GO:0042054 histone methyltransferase activity; GO:0003824 catalytic activity; GO:0070577 lysine-acetylated histone binding; GO:0005488 binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0016740 transferase activity; GO:0042393 histone binding; GO:0035642 histone methyltransferase activity (H3-R17 specific); GO:0003677 DNA binding; GO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding; GO:0016741 transferase activity, transferring one-carbon groups; GO:0003712 transcription cofactor activity; GO:0001067 regulatory region nucleic acid binding; GO:0008469 histone-arginine N-methyltransferase activity; GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding; GO:0001104 RNA polymerase II transcription cofactor activity; GO:0016273 arginine N-methyltransferase activity; GO:0042803 protein homodimerization activity; GO:0044212 transcription regulatory region DNA binding; GO:0003676 nucleic acid binding; GO:0098811 transcriptional repressor activity, RNA polymerase II activating transcription factor binding; GO:0003713 transcription coactivator activity; GO:0008170 N-methyltransferase activity; GO:0000988 transcription factor activity, protein binding; GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding; GO:0008013 beta-catenin binding; ","K05931","CARM1; type I protein arginine methyltransferase [EC:2.1.1.319]","hsa01522 Endocrine resistance - Homo sapiens (human); ","IPR029063; IPR020989; ","\"S-adenosyl-L-methionine-dependent methyltransferase; Histone-arginine methyltransferase CARM1, N-terminal; \"\r"]
["Q86Y82","Syntaxin-12 OS=Homo sapiens OX=9606 GN=STX12","STX12",31.642,32.196,15.9,3,5,3,1.019,1.054,1.083,0.991,0.966,0.988,0.933,0.0236,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0015918 sterol transport; GO:1905037 autophagosome organization; GO:0016043 cellular component organization; GO:0090174 organelle membrane fusion; GO:0046907 intracellular transport; GO:0065008 regulation of biological quality; GO:0015850 organic hydroxy compound transport; GO:0033344 cholesterol efflux; GO:0030301 cholesterol transport; GO:0044699 single-organism process; GO:0006914 autophagy; GO:0044237 cellular metabolic process; GO:0022406 membrane docking; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:1902578 single-organism localization; GO:0022607 cellular component assembly; GO:0070925 organelle assembly; GO:0006886 intracellular protein transport; GO:0044248 cellular catabolic process; GO:0007033 vacuole organization; GO:0044801 single-organism membrane fusion; GO:0034613 cellular protein localization; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0009987 cellular process; GO:0016236 macroautophagy; GO:0044765 single-organism transport; GO:0006869 lipid transport; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0044802 single-organism membrane organization; GO:0016050 vesicle organization; GO:0061025 membrane fusion; GO:0048284 organelle fusion; GO:0010876 lipid localization; GO:0071702 organic substance transport; GO:0048278 vesicle docking; GO:0051641 cellular localization; GO:0006810 transport; GO:0045184 establishment of protein localization; GO:1902589 single-organism organelle organization; GO:0070727 cellular macromolecule localization; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0006906 vesicle fusion; GO:0031647 regulation of protein stability; GO:0051179 localization; GO:0009056 catabolic process; GO:0000045 autophagosome assembly; GO:0050821 protein stabilization; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0098857 membrane microdomain; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0098589 membrane region; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0005768 endosome; GO:0045121 membrane raft; GO:0030139 endocytic vesicle; GO:0043227 membrane-bounded organelle; GO:0000407 pre-autophagosomal structure; GO:0031201 SNARE complex; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0010008 endosome membrane; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0045335 phagocytic vesicle; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043234 protein complex; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0000149 SNARE binding; GO:0005484 SNAP receptor activity; GO:0005515 protein binding; GO:0005488 binding; ","K13813","STX12; syntaxin 12/13","hsa04145 Phagosome - Homo sapiens (human); ","IPR000727; IPR010989; IPR006011; ","\"Target SNARE coiled-coil homology domain; SNARE; Syntaxin, N-terminal domain; \"\r"]
["Q8IU85","Calcium/calmodulin-dependent protein kinase type 1D OS=Homo sapiens OX=9606 GN=CAMK1D","CAMK1D",42.913,17.981,12.2,4,5,4,1.063,1.002,1.122,0.989,0.858,0.981,0.887,0.0997,"cytoplasm\r","GO:0060627 regulation of vesicle-mediated transport; GO:0044700 single organism signaling; GO:0030335 positive regulation of cell migration; GO:0010941 regulation of cell death; GO:0060263 regulation of respiratory burst; GO:0044237 cellular metabolic process; GO:0060267 positive regulation of respiratory burst; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0018105 peptidyl-serine phosphorylation; GO:0050921 positive regulation of chemotaxis; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0090022 regulation of neutrophil chemotaxis; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0031346 positive regulation of cell projection organization; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0051272 positive regulation of cellular component movement; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0051090 regulation of sequence-specific DNA binding transcription factor activity; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0032793 positive regulation of CREB transcription factor activity; GO:0006464 cellular protein modification process; GO:0071624 positive regulation of granulocyte chemotaxis; GO:0002682 regulation of immune system process; GO:0002685 regulation of leukocyte migration; GO:0051094 positive regulation of developmental process; GO:0060548 negative regulation of cell death; GO:0010975 regulation of neuron projection development; GO:0002687 positive regulation of leukocyte migration; GO:0043068 positive regulation of programmed cell death; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0016310 phosphorylation; GO:0018210 peptidyl-threonine modification; GO:0044267 cellular protein metabolic process; GO:0043067 regulation of programmed cell death; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:2000147 positive regulation of cell motility; GO:0051239 regulation of multicellular organismal process; GO:0045597 positive regulation of cell differentiation; GO:0009889 regulation of biosynthetic process; GO:2000145 regulation of cell motility; GO:0018107 peptidyl-threonine phosphorylation; GO:0051171 regulation of nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0030100 regulation of endocytosis; GO:0006950 response to stress; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0050766 positive regulation of phagocytosis; GO:0032101 regulation of response to external stimulus; GO:0030334 regulation of cell migration; GO:0044238 primary metabolic process; GO:0010976 positive regulation of neuron projection development; GO:0006793 phosphorus metabolic process; GO:0050769 positive regulation of neurogenesis; GO:0043412 macromolecule modification; GO:0048584 positive regulation of response to stimulus; GO:0050793 regulation of developmental process; GO:0045666 positive regulation of neuron differentiation; GO:0018209 peptidyl-serine modification; GO:0040017 positive regulation of locomotion; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0006796 phosphate-containing compound metabolic process; GO:0051130 positive regulation of cellular component organization; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0032103 positive regulation of response to external stimulus; GO:1902624 positive regulation of neutrophil migration; GO:0010720 positive regulation of cell development; GO:0050764 regulation of phagocytosis; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0051962 positive regulation of nervous system development; GO:0002688 regulation of leukocyte chemotaxis; GO:0048522 positive regulation of cellular process; GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity; GO:0023052 signaling; GO:0051050 positive regulation of transport; GO:0010942 positive regulation of cell death; GO:0050789 regulation of biological process; GO:0045664 regulation of neuron differentiation; GO:0006954 inflammatory response; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0006952 defense response; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0071622 regulation of granulocyte chemotaxis; GO:0043069 negative regulation of programmed cell death; GO:0045807 positive regulation of endocytosis; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0043065 positive regulation of apoptotic process; GO:0031344 regulation of cell projection organization; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0002690 positive regulation of leukocyte chemotaxis; GO:0006468 protein phosphorylation; GO:0043066 negative regulation of apoptotic process; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:1902622 regulation of neutrophil migration; GO:0006355 regulation of transcription, DNA-templated; GO:0035556 intracellular signal transduction; GO:0051049 regulation of transport; GO:0010556 regulation of macromolecule biosynthetic process; GO:0050920 regulation of chemotaxis; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0018193 peptidyl-amino acid modification; GO:0090023 positive regulation of neutrophil chemotaxis; GO:0044767 single-organism developmental process; GO:0002684 positive regulation of immune system process; GO:0050773 regulation of dendrite development; GO:0051128 regulation of cellular component organization; GO:0040012 regulation of locomotion; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; GO:0050767 regulation of neurogenesis; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0004683 calmodulin-dependent protein kinase activity; GO:0004672 protein kinase activity; GO:0000166 nucleotide binding; GO:0005516 calmodulin binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016301 kinase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0004674 protein serine/threonine kinase activity; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0016740 transferase activity; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K08794","CAMK1; calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]","hsa04925 Aldosterone synthesis and secretion - Homo sapiens (human); hsa04921 Oxytocin signaling pathway - Homo sapiens (human); ","IPR000719; IPR011009; ","Protein kinase domain; Protein kinase-like domain; \r"]
["Q8IUI8","Cytokine receptor-like factor 3 OS=Homo sapiens OX=9606 GN=CRLF3","CRLF3",49.765,3.4359,4.3,2,2,2,0.818,1.008,0.93,1.022,1.069,1.149,1.176,0.078,"cyto_nucl\r","GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0009891 positive regulation of biosynthetic process; GO:0044699 single-organism process; GO:0010564 regulation of cell cycle process; GO:1904894 positive regulation of STAT cascade; GO:0001558 regulation of cell growth; GO:2001141 regulation of RNA biosynthetic process; GO:0010646 regulation of cell communication; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0044770 cell cycle phase transition; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0090068 positive regulation of cell cycle process; GO:0051726 regulation of cell cycle; GO:0000278 mitotic cell cycle; GO:0045926 negative regulation of growth; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044763 single-organism cellular process; GO:0046427 positive regulation of JAK-STAT cascade; GO:0048522 positive regulation of cellular process; GO:0031323 regulation of cellular metabolic process; GO:0030308 negative regulation of cell growth; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0046425 regulation of JAK-STAT cascade; GO:0040008 regulation of growth; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:1903047 mitotic cell cycle process; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0023056 positive regulation of signaling; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0010647 positive regulation of cell communication; GO:0000082 G1/S transition of mitotic cell cycle; GO:0009987 cellular process; GO:0009966 regulation of signal transduction; GO:0044772 mitotic cell cycle phase transition; GO:1904892 regulation of STAT cascade; GO:0045787 positive regulation of cell cycle; GO:0051254 positive regulation of RNA metabolic process; GO:0071156 regulation of cell cycle arrest; GO:0006355 regulation of transcription, DNA-templated; GO:1902531 regulation of intracellular signal transduction; GO:0044843 cell cycle G1/S phase transition; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0031325 positive regulation of cellular metabolic process; GO:0071158 positive regulation of cell cycle arrest; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0022402 cell cycle process; GO:0051128 regulation of cellular component organization; GO:0009967 positive regulation of signal transduction; GO:0031328 positive regulation of cellular biosynthetic process; GO:0048584 positive regulation of response to stimulus; GO:0007049 cell cycle; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0071944 cell periphery; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005886 plasma membrane; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0042802 identical protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR013783; IPR003961; ","Immunoglobulin-like fold; Fibronectin type III; \r"]
["Q8IUZ5","5-phosphohydroxy-L-lysine phospho-lyase OS=Homo sapiens OX=9606 GN=PHYKPL","PHYKPL",49.71,5.1459,4.9,2,2,2,1.18,1.071,1.008,1.029,0.865,0.875,0.85,0.0863,"cytoplasm\r","GO:0044707 single-multicellular organism process; GO:1901606 alpha-amino acid catabolic process; GO:0044236 multicellular organism metabolic process; GO:0009066 aspartate family amino acid metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0044243 multicellular organismal catabolic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0044248 cellular catabolic process; GO:0043170 macromolecule metabolic process; GO:0044259 multicellular organismal macromolecule metabolic process; GO:0009987 cellular process; GO:0030574 collagen catabolic process; GO:0044712 single-organism catabolic process; GO:0044281 small molecule metabolic process; GO:0006553 lysine metabolic process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:0044282 small molecule catabolic process; GO:0044238 primary metabolic process; GO:1901605 alpha-amino acid metabolic process; GO:0032501 multicellular organismal process; GO:0046395 carboxylic acid catabolic process; GO:1901575 organic substance catabolic process; GO:0009068 aspartate family amino acid catabolic process; GO:1901565 organonitrogen compound catabolic process; GO:0044710 single-organism metabolic process; GO:0032963 collagen metabolic process; GO:0016054 organic acid catabolic process; GO:0019752 carboxylic acid metabolic process; GO:0009063 cellular amino acid catabolic process; GO:0006554 lysine catabolic process; GO:0006082 organic acid metabolic process; GO:0009056 catabolic process; GO:0043436 oxoacid metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0016769 transferase activity, transferring nitrogenous groups; GO:0008453 alanine-glyoxylate transaminase activity; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0016829 lyase activity; GO:0043168 anion binding; GO:0005515 protein binding; GO:0008483 transaminase activity; GO:0048037 cofactor binding; GO:0016740 transferase activity; GO:0030170 pyridoxal phosphate binding; ","K18202","AGXT2L2; 5-phosphonooxy-L-lysine phospho-lyase [EC:4.2.3.134]","hsa00310 Lysine degradation - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR015424; IPR015422; IPR015421; ","\"Pyridoxal phosphate-dependent transferase; Pyridoxal phosphate-dependent transferase, major region, subdomain 2; Pyridoxal phosphate-dependent transferase, major region, subdomain 1; \"\r"]
["Q8IVM0","Coiled-coil domain-containing protein 50 OS=Homo sapiens OX=9606 GN=CCDC50","CCDC50",35.822,7.2355,8.5,3,3,3,0.941,0.946,0.919,1.041,1.068,1.084,1.138,0.000945,"nucleus\r","GO:0007600 sensory perception; GO:0007605 sensory perception of sound; GO:0003008 system process; GO:0032501 multicellular organismal process; GO:0050877 neurological system process; GO:0050954 sensory perception of mechanical stimulus; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0031625 ubiquitin protein ligase binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0019899 enzyme binding; GO:0005488 binding; ",{"$nulls":3},"IPR029311; ","\"Coiled-coil domain-containing protein 50,  N-terminal; \"\r"]
["Q8IW75","Serpin A12 OS=Homo sapiens OX=9606 GN=SERPINA12","SERPINA12",47.174,8.1435,8,4,6,4,1.001,0.853,1.041,1.121,0.944,1.044,1.074,0.409,"endoplasmic reticulum\r","GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0019216 regulation of lipid metabolic process; GO:0010466 negative regulation of peptidase activity; GO:0010646 regulation of cell communication; GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling; GO:0090181 regulation of cholesterol metabolic process; GO:0010677 negative regulation of cellular carbohydrate metabolic process; GO:0052548 regulation of endopeptidase activity; GO:0045833 negative regulation of lipid metabolic process; GO:0051055 negative regulation of lipid biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0045721 negative regulation of gluconeogenesis; GO:0010675 regulation of cellular carbohydrate metabolic process; GO:0048522 positive regulation of cellular process; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0048583 regulation of response to stimulus; GO:0046890 regulation of lipid biosynthetic process; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0052547 regulation of peptidase activity; GO:0050794 regulation of cellular process; GO:0043255 regulation of carbohydrate biosynthetic process; GO:0010951 negative regulation of endopeptidase activity; GO:0006111 regulation of gluconeogenesis; GO:0060255 regulation of macromolecule metabolic process; GO:1900076 regulation of cellular response to insulin stimulus; GO:0019218 regulation of steroid metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0010906 regulation of glucose metabolic process; GO:0051346 negative regulation of hydrolase activity; GO:0014066 regulation of phosphatidylinositol 3-kinase signaling; GO:0009889 regulation of biosynthetic process; GO:0023056 positive regulation of signaling; GO:0090207 regulation of triglyceride metabolic process; GO:0010647 positive regulation of cell communication; GO:0009966 regulation of signal transduction; GO:0045861 negative regulation of proteolysis; GO:1902531 regulation of intracellular signal transduction; GO:0046628 positive regulation of insulin receptor signaling pathway; GO:0030162 regulation of proteolysis; GO:0006109 regulation of carbohydrate metabolic process; GO:0009892 negative regulation of metabolic process; GO:0048518 positive regulation of biological process; GO:1900078 positive regulation of cellular response to insulin stimulus; GO:0009890 negative regulation of biosynthetic process; GO:0046626 regulation of insulin receptor signaling pathway; GO:0045912 negative regulation of carbohydrate metabolic process; GO:0051246 regulation of protein metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0009967 positive regulation of signal transduction; GO:0031327 negative regulation of cellular biosynthetic process; GO:0048584 positive regulation of response to stimulus; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0071944 cell periphery; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; ","GO:0004867 serine-type endopeptidase inhibitor activity; GO:0030234 enzyme regulator activity; GO:0030414 peptidase inhibitor activity; GO:0061134 peptidase regulator activity; GO:0061135 endopeptidase regulator activity; GO:0098772 molecular function regulator; GO:0004857 enzyme inhibitor activity; GO:0004866 endopeptidase inhibitor activity; ","K04525",null,null,"IPR023796; ","Serpin domain; \r"]
["Q8IWB7","WD repeat and FYVE domain-containing protein 1 OS=Homo sapiens OX=9606 GN=WDFY1","WDFY1",46.323,33.079,20.5,7,9,7,1.067,1.07,0.991,0.936,0.967,0.969,0.918,0.0367,"cyto_nucl\r","GO:0050794 regulation of cellular process; GO:0034121 regulation of toll-like receptor signaling pathway; GO:0034123 positive regulation of toll-like receptor signaling pathway; GO:0023051 regulation of signaling; GO:0034143 regulation of toll-like receptor 4 signaling pathway; GO:0048522 positive regulation of cellular process; GO:0080134 regulation of response to stress; GO:0031347 regulation of defense response; GO:0048518 positive regulation of biological process; GO:0050776 regulation of immune response; GO:0050789 regulation of biological process; GO:0010646 regulation of cell communication; GO:0045088 regulation of innate immune response; GO:0034141 positive regulation of toll-like receptor 3 signaling pathway; GO:0023056 positive regulation of signaling; GO:0002684 positive regulation of immune system process; GO:0048583 regulation of response to stimulus; GO:0002682 regulation of immune system process; GO:0010647 positive regulation of cell communication; GO:0009967 positive regulation of signal transduction; GO:0034139 regulation of toll-like receptor 3 signaling pathway; GO:0048584 positive regulation of response to stimulus; GO:0009966 regulation of signal transduction; GO:0034145 positive regulation of toll-like receptor 4 signaling pathway; GO:0065007 biological regulation; ","GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005769 early endosome; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0005545 1-phosphatidylinositol binding; GO:0046914 transition metal ion binding; GO:0005488 binding; GO:0005543 phospholipid binding; GO:0035091 phosphatidylinositol binding; GO:0043167 ion binding; GO:0008289 lipid binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0043168 anion binding; GO:0008270 zinc ion binding; ",{"$nulls":3},"IPR000306; IPR017455; IPR013083; IPR017986; IPR015943; IPR011011; ","\"FYVE zinc finger; Zinc finger, FYVE-related; Zinc finger, RING/FYVE/PHD-type; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain; Zinc finger, FYVE/PHD-type; \"\r"]
["Q8IWT6","Volume-regulated anion channel subunit LRRC8A OS=Homo sapiens OX=9606 GN=LRRC8A","LRRC8A",94.198,7.487,3.1,2,3,2,0.916,0.964,0.827,1.119,1.133,1.04,1.216,0.0198,"plasma membrane\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0034220 ion transmembrane transport; GO:0009628 response to abiotic stimulus; GO:0048869 cellular developmental process; GO:0044070 regulation of anion transport; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0098656 anion transmembrane transport; GO:0051234 establishment of localization; GO:0030098 lymphocyte differentiation; GO:0006884 cell volume homeostasis; GO:0042592 homeostatic process; GO:0007165 signal transduction; GO:0030154 cell differentiation; GO:0008361 regulation of cell size; GO:0007154 cell communication; GO:0032879 regulation of localization; GO:0032535 regulation of cellular component size; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0042113 B cell activation; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0006970 response to osmotic stress; GO:0006950 response to stress; GO:0002327 immature B cell differentiation; GO:0051049 regulation of transport; GO:0048731 system development; GO:0002521 leukocyte differentiation; GO:0043269 regulation of ion transport; GO:0044763 single-organism cellular process; GO:0019725 cellular homeostasis; GO:0046649 lymphocyte activation; GO:0002520 immune system development; GO:0002376 immune system process; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0030183 B cell differentiation; GO:0048534 hematopoietic or lymphoid organ development; GO:0030097 hemopoiesis; GO:0006810 transport; GO:0006820 anion transport; GO:0002329 pre-B cell differentiation; GO:0055085 transmembrane transport; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0044767 single-organism developmental process; GO:0006811 ion transport; GO:0090066 regulation of anatomical structure size; GO:0001775 cell activation; GO:0051179 localization; GO:0048856 anatomical structure development; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:1902495 transmembrane transporter complex; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0009986 cell surface; GO:0034702 ion channel complex; GO:1990351 transporter complex; ","GO:0015075 ion transmembrane transporter activity; GO:0022838 substrate-specific channel activity; GO:0005488 binding; GO:0022803 passive transmembrane transporter activity; GO:0005253 anion channel activity; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0005216 ion channel activity; GO:0005225 volume-sensitive anion channel activity; GO:0015267 channel activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0022857 transmembrane transporter activity; GO:0005215 transporter activity; GO:0008509 anion transmembrane transporter activity; ",{"$nulls":3},"IPR032675; IPR021040; ","\"Leucine-rich repeat domain, L domain-like; LRRC8, pannexin-like TM region; \"\r"]
["Q8IWV7","E3 ubiquitin-protein ligase UBR1 OS=Homo sapiens OX=9606 GN=UBR1","UBR1",200.21,27.367,1.4,2,3,2,1.143,0.995,0.856,0.993,1.03,0.996,1.008,0.874,"plasma membrane\r","GO:0001101 response to acid chemical; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0044237 cellular metabolic process; GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway; GO:0008152 metabolic process; GO:0010646 regulation of cell communication; GO:0009719 response to endogenous stimulus; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0070887 cellular response to chemical stimulus; GO:0032007 negative regulation of TOR signaling; GO:0043200 response to amino acid; GO:0051716 cellular response to stimulus; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0071417 cellular response to organonitrogen compound; GO:1901575 organic substance catabolic process; GO:0010243 response to organonitrogen compound; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:1902532 negative regulation of intracellular signal transduction; GO:1901699 cellular response to nitrogen compound; GO:0030163 protein catabolic process; GO:0071230 cellular response to amino acid stimulus; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0036211 protein modification process; GO:0050794 regulation of cellular process; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0071310 cellular response to organic substance; GO:0044267 cellular protein metabolic process; GO:1901700 response to oxygen-containing compound; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:0010498 proteasomal protein catabolic process; GO:0071704 organic substance metabolic process; GO:0032006 regulation of TOR signaling; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0071229 cellular response to acid chemical; GO:0044248 cellular catabolic process; GO:0006508 proteolysis; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:0043632 modification-dependent macromolecule catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:1902531 regulation of intracellular signal transduction; GO:0016567 protein ubiquitination; GO:0019941 modification-dependent protein catabolic process; GO:0048585 negative regulation of response to stimulus; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901701 cellular response to oxygen-containing compound; GO:0032446 protein modification by small protein conjugation; GO:0071495 cellular response to endogenous stimulus; GO:0009057 macromolecule catabolic process; GO:0071233 cellular response to leucine; GO:0043201 response to leucine; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0043412 macromolecule modification; GO:0009056 catabolic process; GO:0065007 biological regulation; ","GO:0000502 proteasome complex; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:1990234 transferase complex; GO:0005829 cytosol; GO:0005623 cell; GO:1905369 endopeptidase complex; GO:1902494 catalytic complex; GO:0005622 intracellular; GO:0044464 cell part; GO:1905368 peptidase complex; GO:0043234 protein complex; GO:0000151 ubiquitin ligase complex; GO:0044444 cytoplasmic part; ","GO:0016597 amino acid binding; GO:0019787 ubiquitin-like protein transferase activity; GO:0043167 ion binding; GO:0043177 organic acid binding; GO:0061659 ubiquitin-like protein ligase activity; GO:0008270 zinc ion binding; GO:0070728 leucine binding; GO:0061630 ubiquitin protein ligase activity; GO:0031406 carboxylic acid binding; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0004842 ubiquitin-protein transferase activity; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0043168 anion binding; GO:0016740 transferase activity; GO:0036094 small molecule binding; ","K10625",null,null,"IPR003769; IPR011991; IPR013083; IPR014719; IPR003126; ","\"Adaptor protein ClpS, core; Winged helix-turn-helix DNA-binding domain; Zinc finger, RING/FYVE/PHD-type; Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like; Zinc finger, UBR-type; \"\r"]
["Q8IWZ3","Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1","ANKHD1",269.45,39.249,2.3,5,8,5,0.993,1.01,0.961,1.061,1.06,1.026,1.062,0.0305,"plasma membrane\r","GO:0002376 immune system process; GO:0006952 defense response; GO:0050896 response to stimulus; GO:0006950 response to stress; GO:0006955 immune response; GO:0045087 innate immune response; ","GO:0044424 intracellular part; GO:0005623 cell; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005515 protein binding; GO:0005488 binding; GO:0003676 nucleic acid binding; ","K16726",null,null,"IPR004087; IPR004088; IPR020683; ","\"K Homology domain; K Homology domain, type 1; Ankyrin repeat-containing domain; \"\r"]
["Q8IXH7","Negative elongation factor C/D OS=Homo sapiens OX=9606 GN=NELFCD","NELFCD",66.246,22.066,4.9,2,2,2,0.799,0.974,0.89,1.101,1.106,1.123,1.25,0.0588,"cytoplasm\r","GO:0097659 nucleic acid-templated transcription; GO:0009891 positive regulation of biosynthetic process; GO:0009058 biosynthetic process; GO:0006354 DNA-templated transcription, elongation; GO:0044237 cellular metabolic process; GO:0051253 negative regulation of RNA metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:1903902 positive regulation of viral life cycle; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0043902 positive regulation of multi-organism process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0050434 positive regulation of viral transcription; GO:0006351 transcription, DNA-templated; GO:1902679 negative regulation of RNA biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0048523 negative regulation of cellular process; GO:0071704 organic substance metabolic process; GO:0045892 negative regulation of transcription, DNA-templated; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0051254 positive regulation of RNA metabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0043900 regulation of multi-organism process; GO:0006368 transcription elongation from RNA polymerase II promoter; GO:0050792 regulation of viral process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0009890 negative regulation of biosynthetic process; GO:0046782 regulation of viral transcription; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0048524 positive regulation of viral process; GO:0006366 transcription from RNA polymerase II promoter; GO:0031325 positive regulation of cellular metabolic process; GO:0010467 gene expression; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0031327 negative regulation of cellular biosynthetic process; GO:1903900 regulation of viral life cycle; GO:0031328 positive regulation of cellular biosynthetic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0032021 NELF complex; GO:0008023 transcription elongation factor complex; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005515 protein binding; GO:0005488 binding; GO:0003676 nucleic acid binding; ","K15181"]
["Q8IXQ6","Poly [ADP-ribose] polymerase 9 OS=Homo sapiens OX=9606 GN=PARP9","PARP9",96.342,9.9656,2.8,2,4,2,0.824,0.79,0.709,1.198,1.352,1.194,1.612,1.4E-3,"cytoplasm\r","GO:0051188 cofactor biosynthetic process; GO:0019362 pyridine nucleotide metabolic process; GO:0051674 localization of cell; GO:0009117 nucleotide metabolic process; GO:0060330 regulation of response to interferon-gamma; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0019363 pyridine nucleotide biosynthetic process; GO:0031347 regulation of defense response; GO:0044237 cellular metabolic process; GO:0072524 pyridine-containing compound metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0072525 pyridine-containing compound biosynthetic process; GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway; GO:0008152 metabolic process; GO:0045088 regulation of innate immune response; GO:0006753 nucleoside phosphate metabolic process; GO:0009108 coenzyme biosynthetic process; GO:0043170 macromolecule metabolic process; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0006732 coenzyme metabolic process; GO:0019359 nicotinamide nucleotide biosynthetic process; GO:0048870 cell motility; GO:0050776 regulation of immune response; GO:0051186 cofactor metabolic process; GO:0090407 organophosphate biosynthetic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0060759 regulation of response to cytokine stimulus; GO:0044710 single-organism metabolic process; GO:0019674 NAD metabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0002682 regulation of immune system process; GO:0040011 locomotion; GO:1901362 organic cyclic compound biosynthetic process; GO:0016477 cell migration; GO:0033554 cellular response to stress; GO:0009165 nucleotide biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0046496 nicotinamide nucleotide metabolic process; GO:0006259 DNA metabolic process; GO:0006302 double-strand break repair; GO:0080134 regulation of response to stress; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0044711 single-organism biosynthetic process; GO:0006950 response to stress; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0006974 cellular response to DNA damage stimulus; GO:0009435 NAD biosynthetic process; GO:0006281 DNA repair; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0019637 organophosphate metabolic process; GO:0006928 movement of cell or subcellular component; GO:0051179 localization; GO:0065007 biological regulation; GO:1901564 organonitrogen compound metabolic process; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0016763 transferase activity, transferring pentosyl groups; GO:0005515 protein binding; GO:0016757 transferase activity, transferring glycosyl groups; GO:0003950 NAD+ ADP-ribosyltransferase activity; GO:0003824 catalytic activity; GO:0016740 transferase activity; GO:0005488 binding; ","K15260",null,null,"IPR002589; IPR012317; ","\"Macro domain; Poly(ADP-ribose) polymerase, catalytic domain; \"\r"]
["Q8IY17","Neuropathy target esterase OS=Homo sapiens OX=9606 GN=PNPLA6","PNPLA6",149.99,22.287,2,2,3,2,1.001,1.264,1.085,0.857,0.999,0.819,0.799,0.0697,"plasma membrane\r","GO:0072359 circulatory system development; GO:0044707 single-multicellular organism process; GO:0046470 phosphatidylcholine metabolic process; GO:0046486 glycerolipid metabolic process; GO:0046434 organophosphate catabolic process; GO:0001568 blood vessel development; GO:0097164 ammonium ion metabolic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0009395 phospholipid catabolic process; GO:0009653 anatomical structure morphogenesis; GO:0001525 angiogenesis; GO:0008152 metabolic process; GO:0046475 glycerophospholipid catabolic process; GO:0044248 cellular catabolic process; GO:0006650 glycerophospholipid metabolic process; GO:0007275 multicellular organism development; GO:0048514 blood vessel morphogenesis; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0009987 cellular process; GO:0006629 lipid metabolic process; GO:0032502 developmental process; GO:0016042 lipid catabolic process; GO:0044712 single-organism catabolic process; GO:0048731 system development; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:0001944 vasculature development; GO:0072358 cardiovascular system development; GO:0044238 primary metabolic process; GO:0032501 multicellular organismal process; GO:1901575 organic substance catabolic process; GO:0048513 animal organ development; GO:0006793 phosphorus metabolic process; GO:0044767 single-organism developmental process; GO:0044710 single-organism metabolic process; GO:0009887 animal organ morphogenesis; GO:0044242 cellular lipid catabolic process; GO:0019637 organophosphate metabolic process; GO:0006644 phospholipid metabolic process; GO:0048856 anatomical structure development; GO:0009056 catabolic process; GO:0046503 glycerolipid catabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044432 endoplasmic reticulum part; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; ","GO:0004622 lysophospholipase activity; GO:0004620 phospholipase activity; GO:0016787 hydrolase activity; GO:0052689 carboxylic ester hydrolase activity; GO:0016298 lipase activity; GO:0003824 catalytic activity; GO:0016788 hydrolase activity, acting on ester bonds; ","K14676","NTE; lysophospholipid hydrolase [EC:3.1.1.5]","hsa00564 Glycerophospholipid metabolism - Homo sapiens (human); ","IPR000595; IPR016035; IPR018490; IPR002641; IPR014710; ","Cyclic nucleotide-binding domain; Acyl transferase/acyl hydrolase/lysophospholipase; Cyclic nucleotide-binding-like; Patatin/Phospholipase A2-related; RmlC-like jelly roll fold; \r"]
["Q8IYB7","DIS3-like exonuclease 2 OS=Homo sapiens OX=9606 GN=DIS3L2","DIS3L2",99.278,2.9747,1.8,2,2,2,0.967,0.931,0.839,1.355,0.923,0.998,1.197,0.25,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0051306 mitotic sister chromatid separation; GO:0022613 ribonucleoprotein complex biogenesis; GO:0007067 mitotic nuclear division; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0008285 negative regulation of cell proliferation; GO:0008152 metabolic process; GO:0000819 sister chromatid segregation; GO:0006364 rRNA processing; GO:1901361 organic cyclic compound catabolic process; GO:0043170 macromolecule metabolic process; GO:0032502 developmental process; GO:0016072 rRNA metabolic process; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0010468 regulation of gene expression; GO:0000278 mitotic cell cycle; GO:0007059 chromosome segregation; GO:0044763 single-organism cellular process; GO:0042254 ribosome biogenesis; GO:1901360 organic cyclic compound metabolic process; GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic; GO:0032501 multicellular organismal process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0016070 RNA metabolic process; GO:0006401 RNA catabolic process; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:1902589 single-organism organelle organization; GO:0034661 ncRNA catabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006402 mRNA catabolic process; GO:0098727 maintenance of cell number; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0051301 cell division; GO:0090305 nucleic acid phosphodiester bond hydrolysis; GO:0016071 mRNA metabolic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0042127 regulation of cell proliferation; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0048285 organelle fission; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic; GO:0010586 miRNA metabolic process; GO:1903047 mitotic cell cycle process; GO:0071704 organic substance metabolic process; GO:0010587 miRNA catabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0044248 cellular catabolic process; GO:0019827 stem cell population maintenance; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0043632 modification-dependent macromolecule catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0000070 mitotic sister chromatid segregation; GO:0006807 nitrogen compound metabolic process; GO:0051304 chromosome separation; GO:0044238 primary metabolic process; GO:1990074 polyuridylation-dependent mRNA catabolic process; GO:0009892 negative regulation of metabolic process; GO:0090501 RNA phosphodiester bond hydrolysis; GO:0051276 chromosome organization; GO:0044767 single-organism developmental process; GO:0098813 nuclear chromosome segregation; GO:0006996 organelle organization; GO:0009057 macromolecule catabolic process; GO:0000280 nuclear division; GO:0010467 gene expression; GO:0022402 cell cycle process; GO:0034660 ncRNA metabolic process; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0000932 P-body; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0043228 non-membrane-bounded organelle; GO:1905354 exoribonuclease complex; GO:0043226 organelle; GO:1902494 catalytic complex; GO:0005622 intracellular; GO:0044464 cell part; GO:0035770 ribonucleoprotein granule; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0044444 cytoplasmic part; GO:0005844 polysome; GO:0000178 exosome (RNase complex); ","GO:0000287 magnesium ion binding; GO:0003723 RNA binding; GO:0000175 3'-5'-exoribonuclease activity; GO:0043167 ion binding; GO:0016896 exoribonuclease activity, producing 5'-phosphomonoesters; GO:0008408 3'-5' exonuclease activity; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0003727 single-stranded RNA binding; GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0008187 poly-pyrimidine tract binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0004532 exoribonuclease activity; GO:0003676 nucleic acid binding; GO:0004518 nuclease activity; GO:0016788 hydrolase activity, acting on ester bonds; GO:0004527 exonuclease activity; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0008266 poly(U) RNA binding; GO:0004540 ribonuclease activity; ","K18758",null,null,"IPR012340; IPR033771; ","\"Nucleic acid-binding, OB-fold; Rrp44-like cold shock domain; \"\r"]
["Q8IYJ3","Synaptotagmin-like protein 1 OS=Homo sapiens OX=9606 GN=SYTL1","SYTL1",61.856,4.0803,3.4,2,3,2,0.916,1.008,0.786,1.139,1.091,1.063,1.215,0.0567,"nucleus\r","GO:0060627 regulation of vesicle-mediated transport; GO:0044700 single organism signaling; GO:0001505 regulation of neurotransmitter levels; GO:0065008 regulation of biological quality; GO:0051046 regulation of secretion; GO:0007269 neurotransmitter secretion; GO:0044699 single-organism process; GO:0015031 protein transport; GO:0099504 synaptic vesicle cycle; GO:0051234 establishment of localization; GO:0099003 vesicle-mediated transport in synapse; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0032879 regulation of localization; GO:0098916 anterograde trans-synaptic signaling; GO:0044801 single-organism membrane fusion; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0051650 establishment of vesicle localization; GO:0048489 synaptic vesicle transport; GO:0044763 single-organism cellular process; GO:0061025 membrane fusion; GO:1903530 regulation of secretion by cell; GO:0023052 signaling; GO:1902582 single-organism intracellular transport; GO:0006810 transport; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0007267 cell-cell signaling; GO:0032940 secretion by cell; GO:0006906 vesicle fusion; GO:0099643 signal release from synapse; GO:0050794 regulation of cellular process; GO:0051640 organelle localization; GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0090174 organelle membrane fusion; GO:0017157 regulation of exocytosis; GO:0099531 presynaptic process involved in chemical synaptic transmission; GO:1902578 single-organism localization; GO:0051648 vesicle localization; GO:0006886 intracellular protein transport; GO:0099537 trans-synaptic signaling; GO:1902580 single-organism cellular localization; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0048791 calcium ion-regulated exocytosis of neurotransmitter; GO:0051049 regulation of transport; GO:0017156 calcium ion regulated exocytosis; GO:0016192 vesicle-mediated transport; GO:0016079 synaptic vesicle exocytosis; GO:0016050 vesicle organization; GO:0044802 single-organism membrane organization; GO:0023061 signal release; GO:0071702 organic substance transport; GO:0048284 organelle fusion; GO:1903305 regulation of regulated secretory pathway; GO:0051656 establishment of organelle localization; GO:0051641 cellular localization; GO:0097480 establishment of synaptic vesicle localization; GO:0045184 establishment of protein localization; GO:0045055 regulated exocytosis; GO:0070727 cellular macromolecule localization; GO:0099536 synaptic signaling; GO:0097479 synaptic vesicle localization; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0007268 chemical synaptic transmission; GO:0051179 localization; GO:0017158 regulation of calcium ion-dependent exocytosis; GO:0006836 neurotransmitter transport; GO:0065007 biological regulation; GO:0006887 exocytosis; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0019898 extrinsic component of membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0098858 actin-based cell projection; GO:0005623 cell; GO:0048770 pigment granule; GO:0070062 extracellular exosome; GO:0070382 exocytic vesicle; GO:0098590 plasma membrane region; GO:0098793 presynapse; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0031528 microvillus membrane; GO:0044456 synapse part; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0042995 cell projection; GO:0042470 melanosome; GO:0019897 extrinsic component of plasma membrane; GO:0012505 endomembrane system; GO:0044463 cell projection part; GO:0005576 extracellular region; GO:0045202 synapse; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0005902 microvillus; GO:0031253 cell projection membrane; GO:0030133 transport vesicle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0000149 SNARE binding; GO:0031267 small GTPase binding; GO:0005544 calcium-dependent phospholipid binding; GO:0042043 neurexin family protein binding; GO:0005102 receptor binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0017137 Rab GTPase binding; GO:0030276 clathrin binding; GO:0017016 Ras GTPase binding; GO:0005488 binding; GO:0005543 phospholipid binding; GO:0008289 lipid binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0043168 anion binding; GO:0005509 calcium ion binding; GO:0051020 GTPase binding; GO:0019905 syntaxin binding; GO:0019899 enzyme binding; ","K17598",null,null,"IPR013083; IPR010911; IPR000008; ","\"Zinc finger, RING/FYVE/PHD-type; Rab-binding domain; C2 domain; \"\r"]
["Q8IYS1","Peptidase M20 domain-containing protein 2 OS=Homo sapiens OX=9606 GN=PM20D2","PM20D2",47.776,1.8486,1.8,1,1,1,1.097,0.627,0.928,1.134,1.221,0.985,1.259,0.227,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0080090 regulation of primary metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0044238 primary metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0051246 regulation of protein metabolic process; GO:0019222 regulation of metabolic process; GO:0006508 proteolysis; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0008233 peptidase activity; GO:0008238 exopeptidase activity; GO:0016787 hydrolase activity; GO:0003824 catalytic activity; GO:0016805 dipeptidase activity; ",{"$nulls":3},"IPR011650; ","\"Peptidase M20, dimerisation domain; \"\r"]
["Q8IYT4","Katanin p60 ATPase-containing subunit A-like 2 OS=Homo sapiens OX=9606 GN=KATNAL2","KATNAL2",61.252,8.6446,2.2,1,5,1,0.913,0.843,0.89,1.119,1.103,1.125,1.265,0.000624,"cytoplasm\r","GO:0016043 cellular component organization; GO:0000226 microtubule cytoskeleton organization; GO:1902589 single-organism organelle organization; GO:0006996 organelle organization; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0097435 supramolecular fiber organization; GO:0007017 microtubule-based process; GO:0071840 cellular component organization or biogenesis; GO:0031122 cytoplasmic microtubule organization; ","GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0005874 microtubule; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0099081 supramolecular polymer; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0005856 cytoskeleton; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0008568 microtubule-severing ATPase activity; GO:0016887 ATPase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0042623 ATPase activity, coupled; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K07767",null,null,"IPR003959; IPR003593; IPR027417; IPR006594; ","\"ATPase, AAA-type, core; AAA+ ATPase domain; P-loop containing nucleoside triphosphate hydrolase; LIS1 homology motif; \"\r"]
["Q8IZL8","Proline-, glutamic acid- and leucine-rich protein 1 OS=Homo sapiens OX=9606 GN=PELP1","PELP1",119.7,2.861,0.8,1,1,1,1.001,0.914,0.908,1.023,0.946,1.208,1.125,0.221,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0043627 response to estrogen; GO:0097659 nucleic acid-templated transcription; GO:0009891 positive regulation of biosynthetic process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0006364 rRNA processing; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0043170 macromolecule metabolic process; GO:0070887 cellular response to chemical stimulus; GO:0016072 rRNA metabolic process; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0051716 cellular response to stimulus; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0048522 positive regulation of cellular process; GO:0042254 ribosome biogenesis; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0051254 positive regulation of RNA metabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0031325 positive regulation of cellular metabolic process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0010467 gene expression; GO:0071391 cellular response to estrogen stimulus; GO:0031328 positive regulation of cellular biosynthetic process; GO:0034660 ncRNA metabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0071339 MLL1 complex; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044665 MLL1/2 complex; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0035097 histone methyltransferase complex; GO:0005730 nucleolus; GO:1990234 transferase complex; GO:0034708 methyltransferase complex; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0000785 chromatin; GO:0035327 transcriptionally active chromatin; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0003682 chromatin binding; GO:0008134 transcription factor binding; ","K16913",null,null,"IPR012583; IPR016024; IPR012980; ","\"Pre-rRNA-processing protein RIX1, N-terminal; Armadillo-type fold; Uncharacterised domain NUC202; \"\r"]
["Q8IZP0","Abl interactor 1 OS=Homo sapiens OX=9606 GN=ABI1","ABI1",55.08,18.274,13.4,5,6,5,0.962,1.029,0.889,1.062,1.025,1.064,1.094,0.106,"cyto_nucl\r","GO:0044700 single organism signaling; GO:0032270 positive regulation of cellular protein metabolic process; GO:0007166 cell surface receptor signaling pathway; GO:0035282 segmentation; GO:0043009 chordate embryonic development; GO:0018212 peptidyl-tyrosine modification; GO:0032989 cellular component morphogenesis; GO:0044237 cellular metabolic process; GO:0072673 lamellipodium morphogenesis; GO:0008285 negative regulation of cell proliferation; GO:0008152 metabolic process; GO:0030036 actin cytoskeleton organization; GO:0061515 myeloid cell development; GO:0044093 positive regulation of molecular function; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0051347 positive regulation of transferase activity; GO:0044419 interspecies interaction between organisms; GO:0009790 embryo development; GO:0044765 single-organism transport; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0008154 actin polymerization or depolymerization; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0048812 neuron projection morphogenesis; GO:0002520 immune system development; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0000902 cell morphogenesis; GO:0048513 animal organ development; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0002682 regulation of immune system process; GO:0006464 cellular protein modification process; GO:0048010 vascular endothelial growth factor receptor signaling pathway; GO:0097435 supramolecular fiber organization; GO:0050794 regulation of cellular process; GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation; GO:0016310 phosphorylation; GO:0044707 single-multicellular organism process; GO:0042127 regulation of cell proliferation; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0007389 pattern specification process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0001756 somitogenesis; GO:0009653 anatomical structure morphogenesis; GO:1902578 single-organism localization; GO:0061098 positive regulation of protein tyrosine kinase activity; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0051338 regulation of transferase activity; GO:0007275 multicellular organism development; GO:0038093 Fc receptor signaling pathway; GO:0007010 cytoskeleton organization; GO:0050778 positive regulation of immune response; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0002253 activation of immune response; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0098751 bone cell development; GO:0044238 primary metabolic process; GO:0060348 bone development; GO:0030182 neuron differentiation; GO:0051247 positive regulation of protein metabolic process; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0031325 positive regulation of cellular metabolic process; GO:0006928 movement of cell or subcellular component; GO:0051179 localization; GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis; GO:0048584 positive regulation of response to stimulus; GO:0043412 macromolecule modification; GO:0097581 lamellipodium organization; GO:0061053 somite development; GO:0038094 Fc-gamma receptor signaling pathway; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0006909 phagocytosis; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0032990 cell part morphogenesis; GO:0009893 positive regulation of metabolic process; GO:0048858 cell projection morphogenesis; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0033674 positive regulation of kinase activity; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0032502 developmental process; GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis; GO:0060429 epithelium development; GO:0030219 megakaryocyte differentiation; GO:0009888 tissue development; GO:0045937 positive regulation of phosphate metabolic process; GO:0061097 regulation of protein tyrosine kinase activity; GO:0048522 positive regulation of cellular process; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0018108 peptidyl-tyrosine phosphorylation; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0030030 cell projection organization; GO:0048813 dendrite morphogenesis; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0002431 Fc receptor mediated stimulatory signaling pathway; GO:0019220 regulation of phosphate metabolic process; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0001501 skeletal system development; GO:0043549 regulation of kinase activity; GO:0045859 regulation of protein kinase activity; GO:0016043 cellular component organization; GO:0016358 dendrite development; GO:0002252 immune effector process; GO:0050730 regulation of peptidyl-tyrosine phosphorylation; GO:0060255 regulation of macromolecule metabolic process; GO:0007015 actin filament organization; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0000904 cell morphogenesis involved in differentiation; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0006468 protein phosphorylation; GO:0016032 viral process; GO:0002757 immune response-activating signal transduction; GO:0009987 cellular process; GO:0009952 anterior/posterior pattern specification; GO:0003002 regionalization; GO:0030099 myeloid cell differentiation; GO:0009792 embryo development ending in birth or egg hatching; GO:0001932 regulation of protein phosphorylation; GO:0031401 positive regulation of protein modification process; GO:0006897 endocytosis; GO:0031175 neuron projection development; GO:0001934 positive regulation of protein phosphorylation; GO:0045860 positive regulation of protein kinase activity; GO:0048518 positive regulation of biological process; GO:0030097 hemopoiesis; GO:0048534 hematopoietic or lymphoid organ development; GO:0043085 positive regulation of catalytic activity; GO:0018193 peptidyl-amino acid modification; GO:0035855 megakaryocyte development; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0002684 positive regulation of immune system process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0030426 growth cone; GO:0044424 intracellular part; GO:0098858 actin-based cell projection; GO:0005623 cell; GO:0032279 asymmetric synapse; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0098590 plasma membrane region; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0014069 postsynaptic density; GO:0030027 lamellipodium; GO:1903561 extracellular vesicle; GO:0097060 synaptic membrane; GO:0030175 filopodium; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0098984 neuron to neuron synapse; GO:0044456 synapse part; GO:0043229 intracellular organelle; GO:0031252 cell leading edge; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0030427 site of polarized growth; GO:0044463 cell projection part; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0045202 synapse; GO:0045211 postsynaptic membrane; GO:0031209 SCAR complex; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0098794 postsynapse; GO:0043234 protein complex; GO:0099572 postsynaptic specialization; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0030295 protein kinase activator activity; GO:0044877 macromolecular complex binding; GO:0030296 protein tyrosine kinase activator activity; GO:0005515 protein binding; GO:0019887 protein kinase regulator activity; GO:0019207 kinase regulator activity; GO:0098772 molecular function regulator; GO:0017124 SH3 domain binding; GO:0050839 cell adhesion molecule binding; GO:0019209 kinase activator activity; GO:0008092 cytoskeletal protein binding; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0045296 cadherin binding; GO:0019904 protein domain specific binding; GO:0008047 enzyme activator activity; GO:0032403 protein complex binding; ",{"$nulls":3},"IPR000727; IPR001452; IPR012849; ","\"Target SNARE coiled-coil homology domain; SH3 domain; Abl-interactor, homeo-domain homologous domain; \"\r"]
["Q8N0X4","Citramalyl-CoA lyase, mitochondrial OS=Homo sapiens OX=9606 GN=CLYBL","CLYBL",37.359,6.8916,6.2,2,2,2,1.112,1.087,1.119,0.878,0.978,0.846,0.814,0.00952,"mitochondria\r",null,"GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044444 cytoplasmic part; ","GO:0000287 magnesium ion binding; GO:0004474 malate synthase activity; GO:0016746 transferase activity, transferring acyl groups; GO:0003824 catalytic activity; GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer; GO:0005488 binding; GO:0043167 ion binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0016740 transferase activity; ","K11390",null,null,"IPR015813; IPR005000; ","Pyruvate/Phosphoenolpyruvate kinase-like domain; HpcH/HpaI aldolase/citrate lyase domain; \r"]
["Q8N126","Cell adhesion molecule 3 OS=Homo sapiens OX=9606 GN=CADM3","CADM3",43.299,8.7625,7.8,3,3,3,1.254,1.146,1.128,0.816,0.819,0.869,0.71,0.000905,"extracellular\r","GO:0016043 cellular component organization; GO:0045216 cell-cell junction organization; GO:0044763 single-organism cellular process; GO:0098609 cell-cell adhesion; GO:0044699 single-organism process; GO:0008037 cell recognition; GO:0022610 biological adhesion; GO:0034330 cell junction organization; GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; GO:0007155 cell adhesion; GO:0034332 adherens junction organization; GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules; GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules; GO:0008104 protein localization; GO:0051179 localization; GO:0033036 macromolecule localization; GO:0009987 cellular process; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0031226 intrinsic component of plasma membrane; GO:0044459 plasma membrane part; GO:0044425 membrane part; GO:0044464 cell part; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0005912 adherens junction; GO:0070161 anchoring junction; GO:0031224 intrinsic component of membrane; GO:0005913 cell-cell adherens junction; GO:0005887 integral component of plasma membrane; GO:0005911 cell-cell junction; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; ","GO:0050839 cell adhesion molecule binding; GO:0060089 molecular transducer activity; GO:0042802 identical protein binding; GO:0004872 receptor activity; GO:0005102 receptor binding; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0046983 protein dimerization activity; GO:0005515 protein binding; ","K06780","CADM3; cell adhesion molecule 3","hsa04514 Cell adhesion molecules (CAMs) - Homo sapiens (human); ","IPR003598; IPR007110; IPR003585; IPR013783; IPR013162; IPR003599; IPR013098; ","\"Immunoglobulin subtype 2; Immunoglobulin-like domain; Neurexin/syndecan/glycophorin C; Immunoglobulin-like fold; CD80-like, immunoglobulin C2-set; Immunoglobulin subtype; Immunoglobulin I-set; \"\r"]
["Q8N183","NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 OS=Homo sapiens OX=9606 GN=NDUFAF2","NDUFAF2",19.856,10.31,13,2,2,2,1.085,0.971,1.016,0.996,0.868,1.075,0.957,0.54,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0050796 regulation of insulin secretion; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0051046 regulation of secretion; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0010646 regulation of cell communication; GO:0006091 generation of precursor metabolites and energy; GO:0090278 negative regulation of peptide hormone secretion; GO:0022607 cellular component assembly; GO:0032879 regulation of localization; GO:0065003 macromolecular complex assembly; GO:0007005 mitochondrion organization; GO:0051051 negative regulation of transport; GO:0050709 negative regulation of protein secretion; GO:0071822 protein complex subunit organization; GO:0010257 NADH dehydrogenase complex assembly; GO:0055114 oxidation-reduction process; GO:0044763 single-organism cellular process; GO:1903531 negative regulation of secretion by cell; GO:1903530 regulation of secretion by cell; GO:0002792 negative regulation of peptide secretion; GO:0051048 negative regulation of secretion; GO:0046883 regulation of hormone secretion; GO:0050789 regulation of biological process; GO:0097031 mitochondrial respiratory chain complex I biogenesis; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0048583 regulation of response to stimulus; GO:0022900 electron transport chain; GO:0010817 regulation of hormone levels; GO:0051223 regulation of protein transport; GO:0070271 protein complex biogenesis; GO:0033108 mitochondrial respiratory chain complex assembly; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0022904 respiratory electron transport chain; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0032844 regulation of homeostatic process; GO:0070201 regulation of establishment of protein localization; GO:0060341 regulation of cellular localization; GO:0032981 mitochondrial respiratory chain complex I assembly; GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus; GO:0002791 regulation of peptide secretion; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0072593 reactive oxygen species metabolic process; GO:0032880 regulation of protein localization; GO:0050708 regulation of protein secretion; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0043623 cellular protein complex assembly; GO:0034622 cellular macromolecular complex assembly; GO:0090087 regulation of peptide transport; GO:0051224 negative regulation of protein transport; GO:0051049 regulation of transport; GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus; GO:0048585 negative regulation of response to stimulus; GO:0032845 negative regulation of homeostatic process; GO:0045333 cellular respiration; GO:0043933 macromolecular complex subunit organization; GO:0046888 negative regulation of hormone secretion; GO:0006996 organelle organization; GO:0090276 regulation of peptide hormone secretion; GO:0046676 negative regulation of insulin secretion; GO:1904950 negative regulation of establishment of protein localization; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044429 mitochondrial part; GO:0031090 organelle membrane; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0005740 mitochondrial envelope; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0031975 envelope; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0009055 electron carrier activity; GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:0003954 NADH dehydrogenase activity; GO:0003824 catalytic activity; GO:0050136 NADH dehydrogenase (quinone) activity; GO:0008137 NADH dehydrogenase (ubiquinone) activity; GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; GO:0016491 oxidoreductase activity; ","K18160","NDUFAF2; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2","hsa04714 Thermogenesis - Homo sapiens (human); "]
["Q8N1B4","Vacuolar protein sorting-associated protein 52 homolog OS=Homo sapiens OX=9606 GN=VPS52","VPS52",82.22,21.107,4.6,2,2,2,0.973,1.072,0.922,1.054,0.944,1.047,1.026,0.663,"cytoplasm\r","GO:0044707 single-multicellular organism process; GO:0046907 intracellular transport; GO:0048568 embryonic organ development; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0048193 Golgi vesicle transport; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0009653 anatomical structure morphogenesis; GO:0030154 cell differentiation; GO:0048729 tissue morphogenesis; GO:0051649 establishment of localization in cell; GO:0007439 ectodermal digestive tract development; GO:0007398 ectoderm development; GO:0007275 multicellular organism development; GO:0016482 cytosolic transport; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0009790 embryo development; GO:0009987 cellular process; GO:0048566 embryonic digestive tract development; GO:0007041 lysosomal transport; GO:0006896 Golgi to vacuole transport; GO:0032502 developmental process; GO:0035295 tube development; GO:0009888 tissue development; GO:0048611 embryonic ectodermal digestive tract development; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0055123 digestive system development; GO:0071702 organic substance transport; GO:0032501 multicellular organismal process; GO:0051641 cellular localization; GO:0016197 endosomal transport; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:0048513 animal organ development; GO:0042147 retrograde transport, endosome to Golgi; GO:0010668 ectodermal cell differentiation; GO:0007034 vacuolar transport; GO:0048565 digestive tract development; GO:0044767 single-organism developmental process; GO:0006892 post-Golgi vesicle-mediated transport; GO:0051179 localization; GO:0032456 endocytic recycling; GO:0048856 anatomical structure development; ","GO:0016020 membrane; GO:1990745 EARP complex; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0032588 trans-Golgi network membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0055037 recycling endosome; GO:0000938 GARP complex; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0098791 Golgi subcompartment; GO:0048471 perinuclear region of cytoplasm; GO:0044431 Golgi apparatus part; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0099023 tethering complex; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0010008 endosome membrane; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0005829 cytosol; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005802 trans-Golgi network; GO:0005794 Golgi apparatus; GO:0043234 protein complex; GO:0031984 organelle subcompartment; GO:0044444 cytoplasmic part; ","GO:0000149 SNARE binding; GO:0031267 small GTPase binding; GO:0017016 Ras GTPase binding; GO:0005488 binding; GO:0005515 protein binding; GO:0051020 GTPase binding; GO:0019905 syntaxin binding; GO:0019899 enzyme binding; GO:0017137 Rab GTPase binding; ","K20298"]
["Q8N1G4","Leucine-rich repeat-containing protein 47 OS=Homo sapiens OX=9606 GN=LRRC47","LRRC47",63.472,66.403,22.5,11,13,11,0.964,1.003,0.955,1.001,0.967,1.021,1.023,0.359,"nucleus\r",null,null,"GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds; GO:0003723 RNA binding; GO:0003824 catalytic activity; GO:0016875 ligase activity, forming carbon-oxygen bonds; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0016874 ligase activity; GO:0004826 phenylalanine-tRNA ligase activity; GO:0005515 protein binding; GO:0004812 aminoacyl-tRNA ligase activity; ",{"$nulls":3},"IPR032675; IPR005146; ","\"Leucine-rich repeat domain, L domain-like; B3/B4 tRNA-binding domain; \"\r"]
["Q8N1Q8","Acyl-coenzyme A thioesterase THEM5 OS=Homo sapiens OX=9606 GN=THEM5","THEM5",27.677,9.4825,7.7,2,3,2,0.883,0.903,0.988,1.092,1.097,1.035,1.162,0.018,"mitochondria\r","GO:0051188 cofactor biosynthetic process; GO:0046949 fatty-acyl-CoA biosynthetic process; GO:0046486 glycerolipid metabolic process; GO:0035337 fatty-acyl-CoA metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0035384 thioester biosynthetic process; GO:0044272 sulfur compound biosynthetic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0046471 phosphatidylglycerol metabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0006650 glycerophospholipid metabolic process; GO:0009108 coenzyme biosynthetic process; GO:0009987 cellular process; GO:0006629 lipid metabolic process; GO:0006790 sulfur compound metabolic process; GO:0071616 acyl-CoA biosynthetic process; GO:0032048 cardiolipin metabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0035383 thioester metabolic process; GO:0035336 long-chain fatty-acyl-CoA metabolic process; GO:0006732 coenzyme metabolic process; GO:0006631 fatty acid metabolic process; GO:0044238 primary metabolic process; GO:0035338 long-chain fatty-acyl-CoA biosynthetic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0006637 acyl-CoA metabolic process; GO:0051186 cofactor metabolic process; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0035965 cardiolipin acyl-chain remodeling; GO:0019752 carboxylic acid metabolic process; GO:0019637 organophosphate metabolic process; GO:0006644 phospholipid metabolic process; GO:0006082 organic acid metabolic process; GO:0043436 oxoacid metabolic process; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0102991 myristoyl-CoA hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0047617 acyl-CoA hydrolase activity; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0016289 CoA hydrolase activity; GO:0016790 thiolester hydrolase activity; GO:0016290 palmitoyl-CoA hydrolase activity; ",{"$nulls":3},"IPR006683; IPR029069; ","Thioesterase domain; HotDog domain; \r"]
["Q8N2S1","Latent-transforming growth factor beta-binding protein 4 OS=Homo sapiens OX=9606 GN=LTBP4","LTBP4",173.43,21.373,3.9,6,7,5,1.194,1.231,1.096,0.893,0.748,0.782,0.688,0.00412,"extracellular\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0009914 hormone transport; GO:0007166 cell surface receptor signaling pathway; GO:0023051 regulation of signaling; GO:0071560 cellular response to transforming growth factor beta stimulus; GO:0044699 single-organism process; GO:0071363 cellular response to growth factor stimulus; GO:0051234 establishment of localization; GO:0006457 protein folding; GO:0001558 regulation of cell growth; GO:0046879 hormone secretion; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0009719 response to endogenous stimulus; GO:0070848 response to growth factor; GO:0042886 amide transport; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0070887 cellular response to chemical stimulus; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0002790 peptide secretion; GO:0044763 single-organism cellular process; GO:0090287 regulation of cellular response to growth factor stimulus; GO:0071559 response to transforming growth factor beta; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:0030072 peptide hormone secretion; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0007267 cell-cell signaling; GO:0032940 secretion by cell; GO:0048583 regulation of response to stimulus; GO:0019222 regulation of metabolic process; GO:0010817 regulation of hormone levels; GO:0048856 anatomical structure development; GO:0015833 peptide transport; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0040008 regulation of growth; GO:0060255 regulation of macromolecule metabolic process; GO:0017015 regulation of transforming growth factor beta receptor signaling pathway; GO:0071310 cellular response to organic substance; GO:0030252 growth hormone secretion; GO:0050896 response to stimulus; GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; GO:1902578 single-organism localization; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0007179 transforming growth factor beta receptor signaling pathway; GO:0023061 signal release; GO:0071702 organic substance transport; GO:0010033 response to organic substance; GO:0030162 regulation of proteolysis; GO:1903844 regulation of cellular response to transforming growth factor beta stimulus; GO:0044767 single-organism developmental process; GO:0071495 cellular response to endogenous stimulus; GO:0051246 regulation of protein metabolic process; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0071705 nitrogen compound transport; GO:0065007 biological regulation; ","GO:0031012 extracellular matrix; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0005578 proteinaceous extracellular matrix; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0005102 receptor binding; GO:0019838 growth factor binding; GO:0005515 protein binding; GO:0005178 integrin binding; GO:0004672 protein kinase activity; GO:0004888 transmembrane signaling receptor activity; GO:0004871 signal transducer activity; GO:0016301 kinase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043169 cation binding; GO:0005539 glycosaminoglycan binding; GO:0016740 transferase activity; GO:0038023 signaling receptor activity; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0050431 transforming growth factor beta binding; GO:0019199 transmembrane receptor protein kinase activity; GO:0019955 cytokine binding; GO:0050839 cell adhesion molecule binding; GO:0060089 molecular transducer activity; GO:0097367 carbohydrate derivative binding; GO:0004872 receptor activity; GO:0005024 transforming growth factor beta-activated receptor activity; GO:0046872 metal ion binding; GO:0004674 protein serine/threonine kinase activity; GO:0005509 calcium ion binding; GO:0004675 transmembrane receptor protein serine/threonine kinase activity; GO:0032403 protein complex binding; GO:0099600 transmembrane receptor activity; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K08023",null,null,"IPR017878; IPR001881; IPR000742; IPR009030; ","TB domain; EGF-like calcium-binding domain; EGF-like domain; Growth factor receptor cysteine-rich domain; \r"]
["Q8N357","Solute carrier family 35 member F6 OS=Homo sapiens OX=9606 GN=SLC35F6","SLC35F6",40.214,5.9531,8.9,3,6,3,1.019,1.13,1.031,0.913,1.047,0.878,0.892,0.138,"plasma membrane\r","GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0065008 regulation of biological quality; GO:0010941 regulation of cell death; GO:0043069 negative regulation of programmed cell death; GO:0042127 regulation of cell proliferation; GO:0007006 mitochondrial membrane organization; GO:0009968 negative regulation of signal transduction; GO:0051129 negative regulation of cellular component organization; GO:0006839 mitochondrial transport; GO:0023051 regulation of signaling; GO:0043067 regulation of programmed cell death; GO:0044699 single-organism process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0010821 regulation of mitochondrion organization; GO:0051234 establishment of localization; GO:2001233 regulation of apoptotic signaling pathway; GO:0010646 regulation of cell communication; GO:0023057 negative regulation of signaling; GO:0046902 regulation of mitochondrial membrane permeability; GO:0010648 negative regulation of cell communication; GO:1901028 regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; GO:0043066 negative regulation of apoptotic process; GO:0032879 regulation of localization; GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; GO:0007005 mitochondrion organization; GO:0090559 regulation of membrane permeability; GO:0009987 cellular process; GO:0009966 regulation of signal transduction; GO:0051051 negative regulation of transport; GO:0010823 negative regulation of mitochondrion organization; GO:0051049 regulation of transport; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0044802 single-organism membrane organization; GO:0033043 regulation of organelle organization; GO:0048585 negative regulation of response to stimulus; GO:0048518 positive regulation of biological process; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0006810 transport; GO:1902589 single-organism organelle organization; GO:0010639 negative regulation of organelle organization; GO:0050789 regulation of biological process; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0048583 regulation of response to stimulus; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0060548 negative regulation of cell death; GO:0042981 regulation of apoptotic process; GO:0008284 positive regulation of cell proliferation; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0005765 lysosomal membrane; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0098852 lytic vacuole membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0005488 binding; "]
["Q8N3D4","EH domain-binding protein 1-like protein 1 OS=Homo sapiens OX=9606 GN=EHBP1L1","EHBP1L1",161.85,36.352,3.3,4,4,3,1.054,1.023,0.992,0.935,1.103,0.903,0.958,0.511,"mitochondria\r",null,"GO:0043226 organelle; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0031410 cytoplasmic vesicle; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0005768 endosome; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR019448; IPR022735; IPR001715; ","EEIG1/EHBP1 N-terminal domain; Domain of unknown function DUF3585; Calponin homology domain; \r"]
["Q8N3F0","Maturin OS=Homo sapiens OX=9606 GN=MTURN","MTURN",14.925,2.3529,6.1,1,1,1,1.105,1.081,1.091,0.984,0.843,0.92,0.838,0.0587,"extracellular\r","GO:0032502 developmental process; GO:0044707 single-multicellular organism process; GO:0044767 single-organism developmental process; GO:0044699 single-organism process; GO:0007275 multicellular organism development; GO:0032501 multicellular organismal process; GO:0048856 anatomical structure development; "]
["Q8N474","Secreted frizzled-related protein 1 OS=Homo sapiens OX=9606 GN=SFRP1","SFRP1",35.385,38.294,21.7,5,6,5,1.106,1.153,1.15,0.883,0.866,0.868,0.768,5.88e-05,"plasma membrane\r",{"$cut":{"chars":27170,"head":"GO:0044700 single organism signaling; GO:0002694 regulation of leukocyte activation; GO:0032872 regulation of stress-activated MAPK cascade; GO:0048732 gland development; GO:0022414 reproductive process; GO:0050796 regulation of insulin secretion; GO:0070555 response to interleukin-1; GO:0010564 regulation of cell cycle process; GO:0001558 regulation of cell growth; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0045577 regulation of B cell differentiation; GO:0051894 positive regulation of focal adhesion assembly; GO:2000051 negative regulation of non-canonical Wnt signaling pathway; GO:0051493 regulation of cytoskeleton organization; GO:0009790 embryo development; GO:0048598 embryonic morphogenesis; GO:0045667 regulation of osteoblast differentiation; GO:0050709 negative regulation of protein secretion; GO:0080090 regulation of primary metabolic process; GO:0050864 regulation of B cell activation; GO:0043508 negative regulation of JUN kinase activity; GO:0060740 prostate gland epithelium morphogenesis; GO:0060828 regulation of canonical Wnt signaling pathway; GO:0090287 regulation of cellular response to growth factor stimulus; GO:0060526 prostate glandular acinus morphogenesis; GO:0071559 response to transforming growth factor beta; GO:0010811 positive regulation of cell-substrate adhesion; GO:1902532 negative regulation of intracellular signal transduction; GO:0060687 regulation of branching involved in prostate gland morphogenesis; GO:0033689 negative regulation of osteoblast proliferation; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0060071 Wnt signaling pathway, planar cell polarity pathway; GO:0032233 positive regulation of actin filament bundle assembly; GO:0045670 regulation of osteoclast differentiation; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0060548 negative regulation of cell death; GO:0071392 cellular response to estradiol stimulus; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0002009 morphogenesis of an epithelium; GO:0044707 single-multicellular organism process; GO:0030850 prostate gland development; GO:0001756 somitogenesis; GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification; GO:1903706 regulation of hemopoiesis; GO:0045892 negative regulation of transcription, DNA-templated; GO:0009653 anatomical structure morphogenesis; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0071229 cellular response to acid chemical; GO:0009889 regulation of biosynthetic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0016331 morphogenesis of embryonic epithelium; GO:0061458 reproductive system development; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0001822 kidney development; GO:0060562 epithelial tube morphogenesis; GO:0034694 response to prostaglandin; GO:0034104 negative regulation of tissue remodeling; GO:0048546 digestive tract morphogenesis; GO:0060284 regulation of cell development; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0051492 regulation of stress fiber assembly; GO:0030510 regulation of BMP signaling pathway; GO:0046888 negative regulation of hormone secretion; GO:0014033 neural crest cell differentiation; GO:0030336 negative regulation of cell migration; GO:0008284 positive regulation of cell proliferation; GO:0051093 negative regulation of developmental process; GO:0034695 response to prostaglandin E; GO:0043627 response to estrogen; GO:0048869 cellular developmental process; GO:0051046 regulation of secretion; GO:0014029 neural crest formation; GO:2000050 regulation of non-canonical Wnt signaling pathway; GO:0045668 negative regulation of osteoblast differentiation; GO:0051253 negative regulation of RNA metabolic process; GO:0001823 mesonephros development; GO:0040013 negative regulation of locomotion; GO:0048729 tissue morphogenesis; GO:0007165 signal transduction; GO:0090278 negative regulation of peptide hormo"}},"GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0031012 extracellular matrix; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0005578 proteinaceous extracellular matrix; GO:0009986 cell surface; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0008233 peptidase activity; GO:0005102 receptor binding; GO:0017147 Wnt-protein binding; GO:0005109 frizzled binding; GO:0043167 ion binding; GO:0008234 cysteine-type peptidase activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0008144 drug binding; GO:0008201 heparin binding; GO:1901681 sulfur compound binding; GO:0004175 endopeptidase activity; GO:0097367 carbohydrate derivative binding; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0001664 G-protein coupled receptor binding; GO:0043168 anion binding; GO:0004197 cysteine-type endopeptidase activity; GO:0005539 glycosaminoglycan binding; ","K02166","SFRP1; secreted frizzled-related protein 1","hsa04310 Wnt signaling pathway - Homo sapiens (human); ","IPR020067; IPR008993; IPR001134; IPR018933; ","\"Frizzled domain; Tissue inhibitor of metalloproteinases-like, OB-fold; Netrin domain; Netrin module, non-TIMP type; \"\r"]
["Q8N4V1","Membrane magnesium transporter 1 OS=Homo sapiens OX=9606 GN=MMGT1","MMGT1",14.686,2.108,6.9,1,1,1,0.953,0.961,0.838,1.135,1.088,1.029,1.182,0.0331,"extracellular\r","GO:0072511 divalent inorganic cation transport; GO:0098655 cation transmembrane transport; GO:0034220 ion transmembrane transport; GO:0098660 inorganic ion transmembrane transport; GO:0030001 metal ion transport; GO:0051234 establishment of localization; GO:0006810 transport; GO:0055085 transmembrane transport; GO:1903830 magnesium ion transmembrane transport; GO:0006812 cation transport; GO:0006811 ion transport; GO:0015693 magnesium ion transport; GO:0051179 localization; GO:0098662 inorganic cation transmembrane transport; GO:0070838 divalent metal ion transport; ","GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0072546 ER membrane protein complex; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0044431 Golgi apparatus part; GO:0031227 intrinsic component of endoplasmic reticulum membrane; GO:0005768 endosome; GO:0031901 early endosome membrane; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0010008 endosome membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0044440 endosomal part; GO:0012505 endomembrane system; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044432 endoplasmic reticulum part; GO:0005794 Golgi apparatus; GO:0030176 integral component of endoplasmic reticulum membrane; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0046873 metal ion transmembrane transporter activity; GO:0072509 divalent inorganic cation transmembrane transporter activity; GO:0015075 ion transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0022890 inorganic cation transmembrane transporter activity; GO:0015095 magnesium ion transmembrane transporter activity; GO:0008324 cation transmembrane transporter activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0022857 transmembrane transporter activity; GO:0005215 transporter activity; "]
["Q8N5K1","CDGSH iron-sulfur domain-containing protein 2 OS=Homo sapiens OX=9606 GN=CISD2","CISD2",15.278,14.309,31.9,4,4,4,0.947,1.041,1.016,1.042,0.971,0.993,1.001,0.978,"mitochondria\r","GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0000422 mitophagy; GO:1903008 organelle disassembly; GO:0044699 single-organism process; GO:0006914 autophagy; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0007005 mitochondrion organization; GO:0044248 cellular catabolic process; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0032502 developmental process; GO:0010259 multicellular organism aging; GO:0031329 regulation of cellular catabolic process; GO:0044712 single-organism catabolic process; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0031323 regulation of cellular metabolic process; GO:0010506 regulation of autophagy; GO:0032501 multicellular organismal process; GO:1902589 single-organism organelle organization; GO:0061726 mitochondrion disassembly; GO:0050789 regulation of biological process; GO:0044767 single-organism developmental process; GO:0044710 single-organism metabolic process; GO:0006996 organelle organization; GO:0007568 aging; GO:0022411 cellular component disassembly; GO:0019222 regulation of metabolic process; GO:0048856 anatomical structure development; GO:0009056 catabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0019867 outer membrane; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0031968 organelle outer membrane; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0044429 mitochondrial part; GO:0005741 mitochondrial outer membrane; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0016021 integral component of membrane; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044432 endoplasmic reticulum part; GO:0031975 envelope; GO:0043234 protein complex; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0003723 RNA binding; GO:0051537 2 iron, 2 sulfur cluster binding; GO:0043167 ion binding; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0042802 identical protein binding; GO:0051536 iron-sulfur cluster binding; GO:0005488 binding; GO:0042803 protein homodimerization activity; GO:0003676 nucleic acid binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0051540 metal cluster binding; ",{"$nulls":3},"IPR018967; IPR019610; ","\"Iron sulphur-containing domain, CDGSH-type; Iron sulphur domain-containing, mitoNEET, N-terminal; \"\r"]
["Q8N684","Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7","CPSF7",52.049,9.5763,9.3,4,5,4,0.999,0.936,0.926,1.052,1.033,1.076,1.105,0.0194,"nucleus\r","GO:0031123 RNA 3'-end processing; GO:0044085 cellular component biogenesis; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0031124 mRNA 3'-end processing; GO:0097659 nucleic acid-templated transcription; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0051259 protein oligomerization; GO:0071704 organic substance metabolic process; GO:0006353 DNA-templated transcription, termination; GO:0000398 mRNA splicing, via spliceosome; GO:0008152 metabolic process; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0051262 protein tetramerization; GO:0022607 cellular component assembly; GO:0006139 nucleobase-containing compound metabolic process; GO:0065003 macromolecular complex assembly; GO:0000375 RNA splicing, via transesterification reactions; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0006396 RNA processing; GO:0018130 heterocycle biosynthetic process; GO:0071822 protein complex subunit organization; GO:0006369 termination of RNA polymerase II transcription; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0006366 transcription from RNA polymerase II promoter; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0070271 protein complex biogenesis; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005849 mRNA cleavage factor complex; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:1901265 nucleoside phosphate binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0036094 small molecule binding; ","K14398","CPSF6_7; cleavage and polyadenylation specificity factor subunit 6/7","hsa03015 mRNA surveillance pathway - Homo sapiens (human); ","IPR000504; IPR012677; ","RNA recognition motif domain; Nucleotide-binding alpha-beta plait domain; \r"]
["Q8N6Y2","Leucine-rich repeat-containing protein 17 OS=Homo sapiens OX=9606 GN=LRRC17","LRRC17",51.799,11.97,9.8,4,4,4,1.252,1.213,1.219,0.717,0.765,0.867,0.638,1.32E-3,"endoplasmic reticulum\r","GO:0050794 regulation of cellular process; GO:0051093 negative regulation of developmental process; GO:0044707 single-multicellular organism process; GO:0002762 negative regulation of myeloid leukocyte differentiation; GO:0045637 regulation of myeloid cell differentiation; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0051239 regulation of multicellular organismal process; GO:1903706 regulation of hemopoiesis; GO:1903707 negative regulation of hemopoiesis; GO:0007275 multicellular organism development; GO:0045596 negative regulation of cell differentiation; GO:0045595 regulation of cell differentiation; GO:0032502 developmental process; GO:0048539 bone marrow development; GO:0045671 negative regulation of osteoclast differentiation; GO:0009888 tissue development; GO:0045638 negative regulation of myeloid cell differentiation; GO:0001503 ossification; GO:0048731 system development; GO:0002376 immune system process; GO:0002520 immune system development; GO:0032501 multicellular organismal process; GO:0048534 hematopoietic or lymphoid organ development; GO:0060348 bone development; GO:0002683 negative regulation of immune system process; GO:1902106 negative regulation of leukocyte differentiation; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0044767 single-organism developmental process; GO:0002761 regulation of myeloid leukocyte differentiation; GO:1902105 regulation of leukocyte differentiation; GO:0002682 regulation of immune system process; GO:0045670 regulation of osteoclast differentiation; GO:0050793 regulation of developmental process; GO:0048856 anatomical structure development; GO:0001501 skeletal system development; GO:2000026 regulation of multicellular organismal development; GO:0065007 biological regulation; ","GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005576 extracellular region; ","GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR000483; IPR032675; ","\"Cysteine-rich flanking region, C-terminal; Leucine-rich repeat domain, L domain-like; \"\r"]
["Q8N8N7","Prostaglandin reductase 2 OS=Homo sapiens OX=9606 GN=PTGR2","PTGR2",38.499,6.6522,8,3,3,3,1.055,1.286,1.087,0.783,0.936,0.88,0.758,0.027,"cytoplasm\r","GO:0033559 unsaturated fatty acid metabolic process; GO:0055114 oxidation-reduction process; GO:0006692 prostanoid metabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901568 fatty acid derivative metabolic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0006631 fatty acid metabolic process; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0044710 single-organism metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0006693 prostaglandin metabolic process; GO:0006082 organic acid metabolic process; GO:0009987 cellular process; GO:0043436 oxoacid metabolic process; GO:0006690 icosanoid metabolic process; GO:0006629 lipid metabolic process; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors; GO:0016614 oxidoreductase activity, acting on CH-OH group of donors; GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; GO:0036132 13-prostaglandin reductase activity; GO:0003824 catalytic activity; GO:0047522 15-oxoprostaglandin 13-oxidase activity; GO:0016491 oxidoreductase activity; ","K13949",null,null,"IPR011032; IPR016040; IPR013149; ","\"GroES-like; NAD(P)-binding domain; Alcohol dehydrogenase, C-terminal; \"\r"]
["Q8N9N2","Activating signal cointegrator 1 complex subunit 1 OS=Homo sapiens OX=9606 GN=ASCC1","ASCC1",45.509,2.3612,2.2,1,2,1,0.915,0.95,0.853,1.061,1.067,1.152,1.207,0.0103,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0006725 cellular aromatic compound metabolic process; GO:0006259 DNA metabolic process; GO:0097659 nucleic acid-templated transcription; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0009058 biosynthetic process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0035510 DNA dealkylation; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0006304 DNA modification; GO:0009987 cellular process; GO:0051716 cellular response to stimulus; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0006355 regulation of transcription, DNA-templated; GO:0006950 response to stress; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0006307 DNA dealkylation involved in DNA repair; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0044238 primary metabolic process; GO:0051252 regulation of RNA metabolic process; GO:1901576 organic substance biosynthetic process; GO:0006974 cellular response to DNA damage stimulus; GO:0044249 cellular biosynthetic process; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0006281 DNA repair; GO:0050789 regulation of biological process; GO:0034645 cellular macromolecule biosynthetic process; GO:0090304 nucleic acid metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006351 transcription, DNA-templated; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0010467 gene expression; GO:0043412 macromolecule modification; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0031594 neuromuscular junction; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005667 transcription factor complex; GO:0005623 cell; GO:0044422 organelle part; GO:0045202 synapse; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005515 protein binding; GO:0005488 binding; GO:0003676 nucleic acid binding; ","K18666",null,null,"IPR004088; IPR009097; IPR019510; ","\"K Homology domain, type 1; RNA ligase/cyclic nucleotide phosphodiesterase; Protein kinase A anchor protein, nuclear localisation signal domain; \"\r"]
["Q8NB37","Glutamine amidotransferase-like class 1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=GATD1","GATD1",23.297,11.942,13.6,2,3,2,0.994,0.871,1.001,1.096,1.008,1.034,1.095,0.149,"extracellular\r",null,"GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ",{"$nulls":4},"IPR029062; ","Class I glutamine amidotransferase-like; \r"]
["Q8NBI5","Solute carrier family 43 member 3 OS=Homo sapiens OX=9606 GN=SLC43A3","SLC43A3",54.528,4.3314,4.1,2,2,2,0.922,0.813,1.037,1.106,1.038,1.079,1.163,0.0993,"plasma membrane\r","GO:0006810 transport; GO:0055085 transmembrane transport; GO:0051179 localization; GO:0051234 establishment of localization; ","GO:0031224 intrinsic component of membrane; GO:0016020 membrane; GO:0016021 integral component of membrane; GO:0044425 membrane part; ",null,"K08230",null,null,"IPR020846; ","Major facilitator superfamily domain; \r"]
["Q8NBJ5","Procollagen galactosyltransferase 1 OS=Homo sapiens OX=9606 GN=COLGALT1","COLGALT1",71.635,8.0922,6.1,4,7,4,1.144,1.094,1.05,0.9,0.955,0.948,0.852,0.0068,"extracellular\r",null,"GO:0005788 endoplasmic reticulum lumen; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044432 endoplasmic reticulum part; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0008194 UDP-glycosyltransferase activity; GO:0016757 transferase activity, transferring glycosyl groups; GO:0035250 UDP-galactosyltransferase activity; GO:0016758 transferase activity, transferring hexosyl groups; GO:0003824 catalytic activity; GO:0016740 transferase activity; GO:0008378 galactosyltransferase activity; GO:0050211 procollagen galactosyltransferase activity; ","K11703","GLT25D; collagen beta-1,O-galactosyltransferase [EC:2.4.1.50]","hsa00514 Other types of O-glycan biosynthesis - Homo sapiens (human); hsa00310 Lysine degradation - Homo sapiens (human); ","IPR029044; ","Nucleotide-diphospho-sugar transferases; \r"]
["Q8NBK3","Sulfatase-modifying factor 1 OS=Homo sapiens OX=9606 GN=SUMF1","SUMF1",40.556,24.185,5.1,1,1,1,0.964,1.05,1.065,0.995,0.949,0.988,0.952,0.234,"extracellular\r","GO:0043687 post-translational protein modification; GO:1903509 liposaccharide metabolic process; GO:0006643 membrane lipid metabolic process; GO:0055114 oxidation-reduction process; GO:0006687 glycosphingolipid metabolic process; GO:0006664 glycolipid metabolic process; GO:0044763 single-organism cellular process; GO:0044267 cellular protein metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0006665 sphingolipid metabolic process; GO:0006464 cellular protein modification process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:0009987 cellular process; GO:0006629 lipid metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0005788 endoplasmic reticulum lumen; GO:0043229 intracellular organelle; GO:0005783 endoplasmic reticulum; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044432 endoplasmic reticulum part; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0043167 ion binding; GO:0046983 protein dimerization activity; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0016491 oxidoreductase activity; ","K13444","SUMF1; formylglycine-generating enzyme [EC:1.8.3.7]","hsa04142 Lysosome - Homo sapiens (human); ","IPR005532; IPR016187; ","Sulfatase-modifying factor enzyme; C-type lectin fold; \r"]
["Q8NBQ5","Estradiol 17-beta-dehydrogenase 11 OS=Homo sapiens OX=9606 GN=HSD17B11","HSD17B11",32.935,27.541,23.7,6,9,6,1.077,1.055,0.957,0.964,0.95,0.972,0.934,0.146,"endoplasmic reticulum\r","GO:0042446 hormone biosynthetic process; GO:0065008 regulation of biological quality; GO:0006710 androgen catabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0006703 estrogen biosynthetic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008610 lipid biosynthetic process; GO:0008209 androgen metabolic process; GO:0008152 metabolic process; GO:1901361 organic cyclic compound catabolic process; GO:0008210 estrogen metabolic process; GO:0009987 cellular process; GO:0006629 lipid metabolic process; GO:0016042 lipid catabolic process; GO:0042445 hormone metabolic process; GO:0044711 single-organism biosynthetic process; GO:0055114 oxidation-reduction process; GO:0044712 single-organism catabolic process; GO:0008202 steroid metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0042447 hormone catabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0034754 cellular hormone metabolic process; GO:0006694 steroid biosynthetic process; GO:1901575 organic substance catabolic process; GO:0044710 single-organism metabolic process; GO:0006706 steroid catabolic process; GO:0010817 regulation of hormone levels; GO:0009056 catabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0065007 biological regulation; ","GO:0043226 organelle; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005811 lipid particle; GO:0005623 cell; GO:0005576 extracellular region; GO:0044444 cytoplasmic part; GO:0043228 non-membrane-bounded organelle; ","GO:0016614 oxidoreductase activity, acting on CH-OH group of donors; GO:0016229 steroid dehydrogenase activity; GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; GO:0004303 estradiol 17-beta-dehydrogenase activity; GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; GO:0003824 catalytic activity; GO:0016491 oxidoreductase activity; ",{"$nulls":3},"IPR016040; ","NAD(P)-binding domain; \r"]
["Q8NC51","Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1","SERBP1",44.965,83.669,44.6,14,17,14,0.816,0.806,0.779,1.234,1.128,1.199,1.483,0.000196,"nucleus\r","GO:0050794 regulation of cellular process; GO:0010468 regulation of gene expression; GO:0010941 regulation of cell death; GO:0065008 regulation of biological quality; GO:0050789 regulation of biological process; GO:0060255 regulation of macromolecule metabolic process; GO:0010608 posttranscriptional regulation of gene expression; GO:0043067 regulation of programmed cell death; GO:0019222 regulation of metabolic process; GO:0043488 regulation of mRNA stability; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; GO:0043487 regulation of RNA stability; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0050839 cell adhesion molecule binding; GO:0003729 mRNA binding; GO:0003723 RNA binding; GO:0003730 mRNA 3'-UTR binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; ","K13199",null,null,"IPR006861; IPR032381; ","\"Hyaluronan/mRNA-binding protein; Intracellular hyaluronan-binding protein 4, N-terminal domain; \"\r"]
["Q8NCE2","Myotubularin-related protein 14 OS=Homo sapiens OX=9606 GN=MTMR14","MTMR14",72.203,30.472,2.9,1,1,1,0.81,1.081,0.949,1.048,1.11,1.005,1.114,0.267,"nucleus\r","GO:0046486 glycerolipid metabolic process; GO:0006661 phosphatidylinositol biosynthetic process; GO:0008654 phospholipid biosynthetic process; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0009058 biosynthetic process; GO:0006914 autophagy; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0008610 lipid biosynthetic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0044248 cellular catabolic process; GO:0006650 glycerophospholipid metabolic process; GO:0046488 phosphatidylinositol metabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0009987 cellular process; GO:0016236 macroautophagy; GO:0006629 lipid metabolic process; GO:0035335 peptidyl-tyrosine dephosphorylation; GO:0044711 single-organism biosynthetic process; GO:0044763 single-organism cellular process; GO:0006470 protein dephosphorylation; GO:0044238 primary metabolic process; GO:0016311 dephosphorylation; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0045017 glycerolipid biosynthetic process; GO:0090407 organophosphate biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0046474 glycerophospholipid biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0019637 organophosphate metabolic process; GO:0006464 cellular protein modification process; GO:0006644 phospholipid metabolic process; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:0009056 catabolic process; ","GO:0031252 cell leading edge; GO:0042995 cell projection; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0048471 perinuclear region of cytoplasm; GO:0001726 ruffle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0044444 cytoplasmic part; ","GO:0004438 phosphatidylinositol-3-phosphatase activity; GO:0004722 protein serine/threonine phosphatase activity; GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity; GO:0016791 phosphatase activity; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0052866 phosphatidylinositol phosphate phosphatase activity; GO:0004721 phosphoprotein phosphatase activity; GO:0042578 phosphoric ester hydrolase activity; GO:0003824 catalytic activity; GO:0004725 protein tyrosine phosphatase activity; GO:0005488 binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0052744 phosphatidylinositol monophosphate phosphatase activity; GO:0034593 phosphatidylinositol bisphosphate phosphatase activity; ","K18086","MTMR14; myotubularin-related protein 14 [EC:3.1.3.64 3.1.3.95]","hsa00562 Inositol phosphate metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa04070 Phosphatidylinositol signaling system - Homo sapiens (human); hsa04140 Autophagy - animal - Homo sapiens (human); ","IPR029021; ","Protein-tyrosine phosphatase-like; \r"]
["Q8ND30","Liprin-beta-2 OS=Homo sapiens OX=9606 GN=PPFIBP2","PPFIBP2",98.543,12.373,3.4,3,3,2,0.779,1.057,1.058,1.001,0.948,1.156,1.073,0.55,"nucleus\r",null,"GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005623 cell; GO:0005622 intracellular; GO:0044464 cell part; GO:0005576 extracellular region; ","GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR013761; IPR001660; ","Sterile alpha motif/pointed domain; Sterile alpha motif domain; \r"]
["Q8NDH3","Probable aminopeptidase NPEPL1 OS=Homo sapiens OX=9606 GN=NPEPL1","NPEPL1",55.86,16.256,6.1,2,2,2,1.046,1.018,0.982,1.002,0.984,0.98,0.974,0.249,"nucleus\r","GO:0006508 proteolysis; GO:0008152 metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0044238 primary metabolic process; GO:0071704 organic substance metabolic process; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; ","GO:0008238 exopeptidase activity; GO:0008233 peptidase activity; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0008235 metalloexopeptidase activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0005515 protein binding; GO:0004177 aminopeptidase activity; GO:0016787 hydrolase activity; GO:0008237 metallopeptidase activity; GO:0030145 manganese ion binding; ","K09611",null,null,"IPR000819; ","\"Peptidase M17, leucyl aminopeptidase, C-terminal; \"\r"]
["Q8NE71","ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1","ABCF1",95.925,43.99,7.2,7,12,7,0.984,1.014,0.989,0.978,1.011,1.025,1.009,0.623,"nucleus\r","GO:0006518 peptide metabolic process; GO:0032270 positive regulation of cellular protein metabolic process; GO:0010608 posttranscriptional regulation of gene expression; GO:0009891 positive regulation of biosynthetic process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0006413 translational initiation; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006412 translation; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0045727 positive regulation of translation; GO:0080090 regulation of primary metabolic process; GO:0043043 peptide biosynthetic process; GO:0048522 positive regulation of cellular process; GO:0043603 cellular amide metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0006810 transport; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0006954 inflammatory response; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0019222 regulation of metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006952 defense response; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0060255 regulation of macromolecule metabolic process; GO:0044267 cellular protein metabolic process; GO:0050896 response to stimulus; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006950 response to stress; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0034248 regulation of cellular amide metabolic process; GO:0055085 transmembrane transport; GO:0051247 positive regulation of protein metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0006417 regulation of translation; GO:0051246 regulation of protein metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0034250 positive regulation of cellular amide metabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0051179 localization; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005840 ribosome; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005635 nuclear envelope; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0042788 polysomal ribosome; GO:0031975 envelope; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0044444 cytoplasmic part; GO:0005844 polysome; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0090079 translation regulator activity, nucleic acid binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0045182 translation regulator activity; GO:0016887 ATPase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0008494 translation activator activity; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003723 RNA binding; GO:0005524 ATP binding; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0043022 ribosome binding; GO:0008135 translation factor activity, RNA binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003676 nucleic acid binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0043021 ribonucleoprotein complex binding; GO:0036094 small molecule binding; ","K06184",null,null,"IPR032781; IPR003593; IPR003439; IPR027417; ","ABC-transporter extension domain; AAA+ ATPase domain; ABC transporter-like; P-loop containing nucleoside triphosphate hydrolase; \r"]
["Q8NEB9","Phosphatidylinositol 3-kinase catalytic subunit type 3 OS=Homo sapiens OX=9606 GN=PIK3C3","PIK3C3",101.55,5.7928,2.4,2,2,2,0.982,0.931,1.112,0.942,0.974,1.061,0.984,0.831,"cyto_nucl\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:1905037 autophagosome organization; GO:0046854 phosphatidylinositol phosphorylation; GO:0044255 cellular lipid metabolic process; GO:0031347 regulation of defense response; GO:0006914 autophagy; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0042157 lipoprotein metabolic process; GO:0098927 vesicle-mediated transport between endosomal compartments; GO:0008610 lipid biosynthetic process; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0032879 regulation of localization; GO:0030258 lipid modification; GO:0009719 response to endogenous stimulus; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0008104 protein localization; GO:0051716 cellular response to stimulus; GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process; GO:0002758 innate immune response-activating signal transduction; GO:0044763 single-organism cellular process; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0090407 organophosphate biosynthetic process; GO:0010243 response to organonitrogen compound; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0044260 cellular macromolecule metabolic process; GO:0006497 protein lipidation; GO:0002682 regulation of immune system process; GO:0051223 regulation of protein transport; GO:0006464 cellular protein modification process; GO:0051301 cell division; GO:0000045 autophagosome assembly; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0016310 phosphorylation; GO:0033554 cellular response to stress; GO:0009267 cellular response to starvation; GO:0006661 phosphatidylinositol biosynthetic process; GO:1901700 response to oxygen-containing compound; GO:0044267 cellular protein metabolic process; GO:0080134 regulation of response to stress; GO:0031349 positive regulation of defense response; GO:0000910 cytokinesis; GO:0044248 cellular catabolic process; GO:0032880 regulation of protein localization; GO:0034613 cellular protein localization; GO:0050778 positive regulation of immune response; GO:0048015 phosphatidylinositol-mediated signaling; GO:0002253 activation of immune response; GO:0044711 single-organism biosynthetic process; GO:0006950 response to stress; GO:0042149 cellular response to glucose starvation; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0071496 cellular response to external stimulus; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0031668 cellular response to extracellular stimulus; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0019637 organophosphate metabolic process; GO:0006644 phospholipid metabolic process; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0043412 macromolecule modification; GO:0010256 endomembrane system organization; GO:0001101 response to acid chemical; GO:0046486 glycerolipid metabolic process; GO:0008654 phospholipid biosynthetic process; GO:0044699 single-organism process; GO:0051046 regulation of secretion; GO:0009058 biosynthetic process; GO:0016485 protein processing; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0048017 inositol lipid-mediated signaling; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0045088 regulation of innate immune response; GO:0006650 glycerophospholipid metabolic process; GO:0046488 phosphatidylinositol metabolic process; GO:0002221 pattern recognition receptor signaling pathway; GO:0007033 vacuole organization; GO:0033036 macromolecule localization; GO:0042158 lipoprotein biosynthetic process; GO:0051726 regulation of cell cycle; GO:0006629 lipid metabolic process; GO:0016236 macroautophagy; GO:0043200 response to amino acid; GO:0034162 toll-like receptor 9 signaling pathway; GO:1903530 regulation of secretion by cell; GO:0023052 signaling; GO:0002764 immune response-regulating signaling pathway; GO:0016197 endosomal transport; GO:0051302 regulation of cell division; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0002224 toll-like receptor signaling pathway; GO:0046474 glycerophospholipid biosynthetic process; GO:0034497 protein localization to pre-autophagosomal structure; GO:0036211 protein modification process; GO:0016043 cellular component organization; GO:0002218 activation of innate immune response; GO:0050896 response to stimulus; GO:0032465 regulation of cytokinesis; GO:0031669 cellular response to nutrient levels; GO:0070201 regulation of establishment of protein localization; GO:0071704 organic substance metabolic process; GO:0009991 response to extracellular stimulus; GO:0006468 protein phosphorylation; GO:0070925 organelle assembly; GO:0002757 immune response-activating signal transduction; GO:0006508 proteolysis; GO:0009059 macromolecule biosynthetic process; GO:0050708 regulation of protein secretion; GO:0016482 cytosolic transport; GO:0009987 cellular process; GO:0045022 early endosome to late endosome transport; GO:0045089 positive regulation of innate immune response; GO:0035556 intracellular signal transduction; GO:0051049 regulation of transport; GO:0016050 vesicle organization; GO:0048518 positive regulation of biological process; GO:0046834 lipid phosphorylation; GO:0044249 cellular biosynthetic process; GO:0045017 glycerolipid biosynthetic process; GO:0051641 cellular localization; GO:0070727 cellular macromolecule localization; GO:0034645 cellular macromolecule biosynthetic process; GO:0002684 positive regulation of immune system process; GO:0010467 gene expression; GO:0042594 response to starvation; GO:0043201 response to leucine; GO:0022402 cell cycle process; GO:0031667 response to nutrient levels; GO:0051604 protein maturation; GO:0007032 endosome organization; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0061695 transferase complex, transferring phosphorus-containing groups; GO:0031090 organelle membrane; GO:0019898 extrinsic component of membrane; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044754 autolysosome; GO:0035032 phosphatidylinositol 3-kinase complex, class III; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005776 autophagosome; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:1902494 catalytic complex; GO:0044441 ciliary part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0030670 phagocytic vesicle membrane; GO:0098805 whole membrane; GO:0005764 lysosome; GO:0005768 endosome; GO:0005767 secondary lysosome; GO:0030139 endocytic vesicle; GO:0043227 membrane-bounded organelle; GO:0005930 axoneme; GO:0000323 lytic vacuole; GO:0005929 cilium; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0042995 cell projection; GO:0005770 late endosome; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0030666 endocytic vesicle membrane; GO:0044430 cytoskeletal part; GO:0097014 ciliary plasm; GO:0044446 intracellular organelle part; GO:0030496 midbody; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0045335 phagocytic vesicle; GO:1990234 transferase complex; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005773 vacuole; GO:0005942 phosphatidylinositol 3-kinase complex; GO:0044444 cytoplasmic part; ","GO:0052742 phosphatidylinositol kinase activity; GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0004672 protein kinase activity; GO:0035004 phosphatidylinositol 3-kinase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016301 kinase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0016303 1-phosphatidylinositol-3-kinase activity; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K00914","PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]","hsa00562 Inositol phosphate metabolism - Homo sapiens (human); hsa05152 Tuberculosis - Homo sapiens (human); hsa04371 Apelin signaling pathway - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa04070 Phosphatidylinositol signaling system - Homo sapiens (human); hsa05167 Kaposi's sarcoma-associated herpesvirus infection - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); hsa04140 Autophagy - animal - Homo sapiens (human); hsa04136 Autophagy - other - Homo sapiens (human); ","IPR000403; IPR001263; IPR002420; IPR016024; IPR000008; IPR011009; ","\"Phosphatidylinositol 3-/4-kinase, catalytic domain; Phosphoinositide 3-kinase, accessory (PIK) domain; Phosphatidylinositol 3-kinase, C2 domain; Armadillo-type fold; C2 domain; Protein kinase-like domain; \"\r"]
["Q8NEZ3","WD repeat-containing protein 19 OS=Homo sapiens OX=9606 GN=WDR19","WDR19",151.58,1.8151,1,1,1,1,1.061,1.011,1.052,0.979,0.982,0.929,0.925,0.0289,"cytoplasm\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0098840 protein transport along microtubule; GO:0061053 somite development; GO:0007166 cell surface receptor signaling pathway; GO:0022414 reproductive process; GO:0061055 myotome development; GO:0043009 chordate embryonic development; GO:0048869 cellular developmental process; GO:0032989 cellular component morphogenesis; GO:0060271 cilium assembly; GO:0044699 single-organism process; GO:0051668 localization within membrane; GO:0007224 smoothened signaling pathway; GO:0050877 neurological system process; GO:0015031 protein transport; GO:0044782 cilium organization; GO:0051234 establishment of localization; GO:0009953 dorsal/ventral pattern formation; GO:0007165 signal transduction; GO:0010970 transport along microtubule; GO:0035107 appendage morphogenesis; GO:0051649 establishment of localization in cell; GO:0048562 embryonic organ morphogenesis; GO:0007154 cell communication; GO:0031076 embryonic camera-type eye development; GO:0022607 cellular component assembly; GO:0044702 single organism reproductive process; GO:0060173 limb development; GO:0048706 embryonic skeletal system development; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0009790 embryo development; GO:0090596 sensory organ morphogenesis; GO:0048598 embryonic morphogenesis; GO:0035113 embryonic appendage morphogenesis; GO:0044765 single-organism transport; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0035295 tube development; GO:0051716 cellular response to stimulus; GO:0060429 epithelium development; GO:0003006 developmental process involved in reproduction; GO:0009888 tissue development; GO:0072657 protein localization to membrane; GO:0048608 reproductive structure development; GO:0044763 single-organism cellular process; GO:0023052 signaling; GO:0035735 intraciliary transport involved in cilium assembly; GO:0032501 multicellular organismal process; GO:1902582 single-organism intracellular transport; GO:0000902 cell morphogenesis; GO:0006810 transport; GO:0043113 receptor clustering; GO:1902589 single-organism organelle organization; GO:0048513 animal organ development; GO:0043583 ear development; GO:0050789 regulation of biological process; GO:0001701 in utero embryonic development; GO:0030030 cell projection organization; GO:0009887 animal organ morphogenesis; GO:0099118 microtubule-based protein transport; GO:0048856 anatomical structure development; GO:0001501 skeletal system development; GO:0031503 protein complex localization; GO:0050794 regulation of cellular process; GO:0000003 reproduction; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0043010 camera-type eye development; GO:0048568 embryonic organ development; GO:0007389 pattern specification process; GO:0008406 gonad development; GO:0021915 neural tube development; GO:0050896 response to stimulus; GO:0099111 microtubule-based transport; GO:0030705 cytoskeleton-dependent intracellular transport; GO:0009653 anatomical structure morphogenesis; GO:0001654 eye development; GO:0021904 dorsal/ventral neural tube patterning; GO:1902578 single-organism localization; GO:0070925 organelle assembly; GO:0006886 intracellular protein transport; GO:0007548 sex differentiation; GO:1904888 cranial skeletal system development; GO:1902580 single-organism cellular localization; GO:0048704 embryonic skeletal system morphogenesis; GO:0007275 multicellular organism development; GO:0034613 cellular protein localization; GO:0061458 reproductive system development; GO:0009987 cellular process; GO:0045137 development of primary sexual characteristics; GO:0003008 system process; GO:0003002 regionalization; GO:0021532 neural tube patterning; GO:0048731 system development; GO:0009792 embryo development ending in birth or egg hatching; GO:0035721 intraciliary retrograde transport; GO:0055123 digestive system development; GO:0071702 organic substance transport; GO:0042073 intraciliary transport; GO:0007017 microtubule-based process; GO:0030031 cell projection assembly; GO:0048705 skeletal system morphogenesis; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0048736 appendage development; GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning; GO:0007018 microtubule-based movement; GO:0070727 cellular macromolecule localization; GO:0035108 limb morphogenesis; GO:0030326 embryonic limb morphogenesis; GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway; GO:0044767 single-organism developmental process; GO:0006996 organelle organization; GO:0042471 ear morphogenesis; GO:0048701 embryonic cranial skeleton morphogenesis; GO:0006928 movement of cell or subcellular component; GO:0007423 sensory organ development; GO:0051179 localization; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0035869 ciliary transition zone; GO:0005737 cytoplasm; GO:0097730 non-motile cilium; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0030990 intraciliary transport particle; GO:0005623 cell; GO:0097731 9+0 non-motile cilium; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044441 ciliary part; GO:0044464 cell part; GO:0005622 intracellular; GO:0001750 photoreceptor outer segment; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0030991 intraciliary transport particle A; GO:0043233 organelle lumen; GO:0005929 cilium; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0097542 ciliary tip; GO:0044463 cell projection part; GO:0031514 motile cilium; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0032391 photoreceptor connecting cilium; GO:0097733 photoreceptor cell cilium; GO:0043234 protein complex; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0005488 binding; ","K19671",null,null,"IPR011990; IPR017986; IPR015943; ","Tetratricopeptide-like helical domain; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain; \r"]
["Q8NEZ5","F-box only protein 22 OS=Homo sapiens OX=9606 GN=FBXO22","FBXO22",44.508,9.6909,3.5,1,1,1,0.869,0.895,0.845,0.994,1.133,1.25,1.294,0.0206,"cytoplasm\r","GO:0032270 positive regulation of cellular protein metabolic process; GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0031331 positive regulation of cellular catabolic process; GO:0048634 regulation of muscle organ development; GO:0051169 nuclear transport; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:0031396 regulation of protein ubiquitination; GO:1903364 positive regulation of cellular protein catabolic process; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0048742 regulation of skeletal muscle fiber development; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0010830 regulation of myotube differentiation; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:1903362 regulation of cellular protein catabolic process; GO:0051147 regulation of muscle cell differentiation; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0048522 positive regulation of cellular process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0031323 regulation of cellular metabolic process; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:2000058 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0016202 regulation of striated muscle tissue development; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0030163 protein catabolic process; GO:0061136 regulation of proteasomal protein catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006464 cellular protein modification process; GO:0006913 nucleocytoplasmic transport; GO:0036211 protein modification process; GO:2000026 regulation of multicellular organismal development; GO:0048641 regulation of skeletal muscle tissue development; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0033554 cellular response to stress; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0009267 cellular response to starvation; GO:0044257 cellular protein catabolic process; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:0060255 regulation of macromolecule metabolic process; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0050896 response to stimulus; GO:0031669 cellular response to nutrient levels; GO:0051239 regulation of multicellular organismal process; GO:0000209 protein polyubiquitination; GO:0071704 organic substance metabolic process; GO:0009991 response to extracellular stimulus; GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:1903322 positive regulation of protein modification by small protein conjugation or removal; GO:0045862 positive regulation of proteolysis; GO:0009896 positive regulation of catabolic process; GO:0044248 cellular catabolic process; GO:0006508 proteolysis; GO:0042176 regulation of protein catabolic process; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0043632 modification-dependent macromolecule catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0016567 protein ubiquitination; GO:0006950 response to stress; GO:0019941 modification-dependent protein catabolic process; GO:1901861 regulation of muscle tissue development; GO:0060284 regulation of cell development; GO:1901800 positive regulation of proteasomal protein catabolic process; GO:0031401 positive regulation of protein modification process; GO:0071496 cellular response to external stimulus; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0051153 regulation of striated muscle cell differentiation; GO:0031668 cellular response to extracellular stimulus; GO:0051247 positive regulation of protein metabolic process; GO:0032446 protein modification by small protein conjugation; GO:0031398 positive regulation of protein ubiquitination; GO:0051246 regulation of protein metabolic process; GO:0009057 macromolecule catabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0042594 response to starvation; GO:0031667 response to nutrient levels; GO:0045732 positive regulation of protein catabolic process; GO:0043412 macromolecule modification; GO:0051179 localization; GO:0009056 catabolic process; GO:0050793 regulation of developmental process; GO:0065007 biological regulation; GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0030016 myofibril; GO:0005737 cytoplasm; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0030018 Z disc; GO:0005829 cytosol; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0031674 I band; GO:0044422 organelle part; GO:0099081 supramolecular polymer; GO:0043228 non-membrane-bounded organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:0043292 contractile fiber; GO:0030017 sarcomere; GO:0044449 contractile fiber part; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0019787 ubiquitin-like protein transferase activity; GO:0003824 catalytic activity; GO:0016740 transferase activity; GO:0005488 binding; GO:0004842 ubiquitin-protein transferase activity; ","K10302",null,null,"IPR001810; IPR019494; ","\"F-box domain; FIST, C-domain; \"\r"]
["Q8NFD5","AT-rich interactive domain-containing protein 1B OS=Homo sapiens OX=9606 GN=ARID1B","ARID1B",236.12,7.6373,1.8,3,3,3,0.842,0.962,0.93,1.071,1.113,1.078,1.193,0.013,"cytoplasm\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0097026 dendritic cell dendrite assembly; GO:0097659 nucleic acid-templated transcription; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0009891 positive regulation of biosynthetic process; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0007270 neuron-neuron synaptic transmission; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0048096 chromatin-mediated maintenance of transcription; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0022607 cellular component assembly; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0098916 anterograde trans-synaptic signaling; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0045815 positive regulation of gene expression, epigenetic; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0032774 RNA biosynthetic process; GO:0023052 signaling; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0007267 cell-cell signaling; GO:0006351 transcription, DNA-templated; GO:0030030 cell projection organization; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006325 chromatin organization; GO:0048856 anatomical structure development; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0016358 dendrite development; GO:0006338 chromatin remodeling; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0048468 cell development; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0051171 regulation of nitrogen compound metabolic process; GO:0099537 trans-synaptic signaling; GO:0034641 cellular nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0016569 covalent chromatin modification; GO:0007275 multicellular organism development; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0051254 positive regulation of RNA metabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0048731 system development; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:0031175 neuron projection development; GO:1901576 organic substance biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0030031 cell projection assembly; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0030182 neuron differentiation; GO:0040029 regulation of gene expression, epigenetic; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0060996 dendritic spine development; GO:0051276 chromosome organization; GO:0099536 synaptic signaling; GO:0044767 single-organism developmental process; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0010467 gene expression; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0043412 macromolecule modification; GO:0031328 positive regulation of cellular biosynthetic process; GO:0007268 chemical synaptic transmission; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0043229 intracellular organelle; GO:0071944 cell periphery; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0070603 SWI/SNF superfamily-type complex; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0005886 plasma membrane; GO:0071565 nBAF complex; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0043234 protein complex; GO:0090544 BAF-type complex; GO:0097458 neuron part; GO:0016514 SWI/SNF complex; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003677 DNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0003713 transcription coactivator activity; GO:0005515 protein binding; GO:0003712 transcription cofactor activity; GO:0000988 transcription factor activity, protein binding; ","K11653","ARID1; AT-rich interactive domain-containing protein 1","hsa05225 Hepatocellular carcinoma - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); ","IPR033388; IPR011989; IPR001606; ","\"SWI/SNF-like complex subunit BAF250, C-terminal; Armadillo-like helical; ARID DNA-binding domain; \"\r"]
["Q8NFQ8","Torsin-1A-interacting protein 2 OS=Homo sapiens OX=9606 GN=TOR1AIP2","TOR1AIP2",51.263,21.405,3.2,1,1,1,0.821,1.012,0.951,1.08,1.146,0.989,1.155,0.125,"cytoplasm\r","GO:0016043 cellular component organization; GO:0006997 nucleus organization; GO:0010256 endomembrane system organization; GO:0044763 single-organism cellular process; GO:0044802 single-organism membrane organization; GO:0044699 single-organism process; GO:0051641 cellular localization; GO:0006998 nuclear envelope organization; GO:0043085 positive regulation of catalytic activity; GO:0070727 cellular macromolecule localization; GO:0051336 regulation of hydrolase activity; GO:0051345 positive regulation of hydrolase activity; GO:0043462 regulation of ATPase activity; GO:0006996 organelle organization; GO:0050790 regulation of catalytic activity; GO:0061024 membrane organization; GO:0044093 positive regulation of molecular function; GO:0065009 regulation of molecular function; GO:0032781 positive regulation of ATPase activity; GO:0033365 protein localization to organelle; GO:0051179 localization; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0034613 cellular protein localization; GO:0034504 protein localization to nucleus; GO:0009987 cellular process; GO:0090435 protein localization to nuclear envelope; GO:0007029 endoplasmic reticulum organization; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0005635 nuclear envelope; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031965 nuclear membrane; GO:0005634 nucleus; GO:0044432 endoplasmic reticulum part; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0031975 envelope; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0001671 ATPase activator activity; GO:0030234 enzyme regulator activity; GO:0051117 ATPase binding; GO:0005488 binding; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0005515 protein binding; GO:0060590 ATPase regulator activity; GO:0098772 molecular function regulator; GO:0019899 enzyme binding; GO:0008047 enzyme activator activity; "]
["Q8NHP8","Putative phospholipase B-like 2 OS=Homo sapiens OX=9606 GN=PLBD2","PLBD2",65.471,10.004,6.6,4,5,4,0.925,1.053,1.057,1.068,1.069,0.973,1.025,0.662,"extracellular\r","GO:0016042 lipid catabolic process; GO:1901575 organic substance catabolic process; GO:0008152 metabolic process; GO:0044710 single-organism metabolic process; GO:0044712 single-organism catabolic process; GO:0044699 single-organism process; GO:0044238 primary metabolic process; GO:0009056 catabolic process; GO:0071704 organic substance metabolic process; GO:0006629 lipid metabolic process; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0043202 lysosomal lumen; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0044437 vacuolar part; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0005773 vacuole; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; ","GO:0016787 hydrolase activity; GO:0003824 catalytic activity; "]
["Q8NI22","Multiple coagulation factor deficiency protein 2 OS=Homo sapiens OX=9606 GN=MCFD2","MCFD2",16.39,7.2692,11.6,1,1,1,0.952,1.101,0.924,0.952,0.904,1.175,1.018,0.889,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:0006901 vesicle coating; GO:0043413 macromolecule glycosylation; GO:0048207 vesicle targeting, rough ER to cis-Golgi; GO:0048208 COPII vesicle coating; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0018196 peptidyl-asparagine modification; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:1901137 carbohydrate derivative biosynthetic process; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0048199 vesicle targeting, to, from or within Golgi; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0006487 protein N-linked glycosylation; GO:0051650 establishment of vesicle localization; GO:0006486 protein glycosylation; GO:0009101 glycoprotein biosynthetic process; GO:0071822 protein complex subunit organization; GO:0044763 single-organism cellular process; GO:0009100 glycoprotein metabolic process; GO:0006810 transport; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0070271 protein complex biogenesis; GO:0036211 protein modification process; GO:0051640 organelle localization; GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0044267 cellular protein metabolic process; GO:0048193 Golgi vesicle transport; GO:0006903 vesicle targeting; GO:0071704 organic substance metabolic process; GO:0051648 vesicle localization; GO:1901135 carbohydrate derivative metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0070085 glycosylation; GO:0006461 protein complex assembly; GO:0090114 COPII-coated vesicle budding; GO:0016192 vesicle-mediated transport; GO:0016050 vesicle organization; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0051656 establishment of organelle localization; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0051641 cellular localization; GO:0018193 peptidyl-amino acid modification; GO:0045184 establishment of protein localization; GO:0018279 protein N-linked glycosylation via asparagine; GO:0034645 cellular macromolecule biosynthetic process; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0006900 membrane budding; GO:0051179 localization; GO:0043412 macromolecule modification; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0071840 cellular component organization or biogenesis; ","GO:0030658 transport vesicle membrane; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0030662 coated vesicle membrane; GO:0044422 organelle part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0044431 Golgi apparatus part; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0012507 ER to Golgi transport vesicle membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012506 vesicle membrane; GO:0030134 ER to Golgi transport vesicle; GO:0012505 endomembrane system; GO:0030135 coated vesicle; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044432 endoplasmic reticulum part; GO:0005793 endoplasmic reticulum-Golgi intermediate compartment; GO:0030133 transport vesicle; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005509 calcium ion binding; GO:0005488 binding; GO:0043167 ion binding; ","K20364",null,null,"IPR011992; IPR002048; ","EF-hand domain pair; EF-hand domain; \r"]
["Q8TAE8","Growth arrest and DNA damage-inducible proteins-interacting protein 1 OS=Homo sapiens OX=9606 GN=GADD45GIP1","GADD45GIP1",25.384,2.1186,4.5,1,1,1,0.799,0.894,0.93,1.038,1.038,1.288,1.283,0.0448,"mitochondria\r","GO:0043467 regulation of generation of precursor metabolites and energy; GO:0006518 peptide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0002082 regulation of oxidative phosphorylation; GO:0044237 cellular metabolic process; GO:0043241 protein complex disassembly; GO:0071850 mitotic cell cycle arrest; GO:0008152 metabolic process; GO:0045930 negative regulation of mitotic cell cycle; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006412 translation; GO:0044419 interspecies interaction between organisms; GO:0051726 regulation of cell cycle; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0071822 protein complex subunit organization; GO:0045937 positive regulation of phosphate metabolic process; GO:0080090 regulation of primary metabolic process; GO:0043043 peptide biosynthetic process; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0043603 cellular amide metabolic process; GO:0070126 mitochondrial translational termination; GO:0031323 regulation of cellular metabolic process; GO:0051704 multi-organism process; GO:0006415 translational termination; GO:0050789 regulation of biological process; GO:0070125 mitochondrial translational elongation; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0045981 positive regulation of nucleotide metabolic process; GO:0006140 regulation of nucleotide metabolic process; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0007346 regulation of mitotic cell cycle; GO:0045786 negative regulation of cell cycle; GO:0042127 regulation of cell proliferation; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0009118 regulation of nucleoside metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:1900544 positive regulation of purine nucleotide metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0016032 viral process; GO:0043624 cellular protein complex disassembly; GO:0051171 regulation of nitrogen compound metabolic process; GO:1903862 positive regulation of oxidative phosphorylation; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:1903578 regulation of ATP metabolic process; GO:0006414 translational elongation; GO:0007050 cell cycle arrest; GO:0032984 macromolecular complex disassembly; GO:0006807 nitrogen compound metabolic process; GO:0032543 mitochondrial translation; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:1900542 regulation of purine nucleotide metabolic process; GO:0045979 positive regulation of nucleoside metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0031325 positive regulation of cellular metabolic process; GO:0022411 cellular component disassembly; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0010467 gene expression; GO:0022402 cell cycle process; GO:0043604 amide biosynthetic process; GO:1903580 positive regulation of ATP metabolic process; GO:0007049 cell cycle; GO:0008284 positive regulation of cell proliferation; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:1901564 organonitrogen compound metabolic process; ","GO:0005840 ribosome; GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005761 mitochondrial ribosome; GO:0005623 cell; GO:0000313 organellar ribosome; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0005515 protein binding; GO:0005488 binding; "]
["Q8TAQ2","SWI/SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2","SMARCC2",132.88,26.769,11.2,13,13,11,1.111,1.169,0.996,0.987,0.865,0.9,0.84,0.0473,"nucleus\r","GO:0097659 nucleic acid-templated transcription; GO:0009891 positive regulation of biosynthetic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0051253 negative regulation of RNA metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0071824 protein-DNA complex subunit organization; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0006333 chromatin assembly or disassembly; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0031498 chromatin disassembly; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0032774 RNA biosynthetic process; GO:0043044 ATP-dependent chromatin remodeling; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0032501 multicellular organismal process; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0006337 nucleosome disassembly; GO:1902679 negative regulation of RNA biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0006325 chromatin organization; GO:0048856 anatomical structure development; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0034728 nucleosome organization; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0006338 chromatin remodeling; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0071704 organic substance metabolic process; GO:0045892 negative regulation of transcription, DNA-templated; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0016569 covalent chromatin modification; GO:0007275 multicellular organism development; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0032986 protein-DNA complex disassembly; GO:0051254 positive regulation of RNA metabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0048731 system development; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0032984 macromolecular complex disassembly; GO:0006807 nitrogen compound metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0009892 negative regulation of metabolic process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0009890 negative regulation of biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0051276 chromosome organization; GO:0044767 single-organism developmental process; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0022411 cellular component disassembly; GO:0010467 gene expression; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0043412 macromolecule modification; GO:0031328 positive regulation of cellular biosynthetic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0070603 SWI/SNF superfamily-type complex; GO:0044422 organelle part; GO:0071565 nBAF complex; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044454 nuclear chromosome part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005694 chromosome; GO:0000790 nuclear chromatin; GO:0071564 npBAF complex; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0000785 chromatin; GO:0000228 nuclear chromosome; GO:0043234 protein complex; GO:0090544 BAF-type complex; GO:0016514 SWI/SNF complex; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003677 DNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0003713 transcription coactivator activity; GO:0005515 protein binding; GO:0003712 transcription cofactor activity; GO:0000988 transcription factor activity, protein binding; ","K11649","SMARCC; SWI/SNF related-matrix-associated actin-dependent regulator of chromatin subfamily C","hsa05225 Hepatocellular carcinoma - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); ","IPR011991; IPR032450; IPR017884; IPR000953; IPR032451; IPR001005; IPR032448; IPR009057; IPR007526; IPR001357; ","\"Winged helix-turn-helix DNA-binding domain; SMARCC, N-terminal; SANT domain; Chromo/chromo shadow domain; SMARCC, C-terminal; SANT/Myb domain; SMARCC, SWIRM-associated domain; Homeobox domain-like; SWIRM domain; BRCT domain; \"\r"]
["Q8TB52","F-box only protein 30 OS=Homo sapiens OX=9606 GN=FBXO30","FBXO30",82.303,-2,0.9,1,1,1,1.218,1.109,1.026,0.996,0.662,1.02,0.799,0.181,"cyto_nucl\r","GO:0016567 protein ubiquitination; GO:0044267 cellular protein metabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0000209 protein polyubiquitination; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0032446 protein modification by small protein conjugation; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:0009987 cellular process; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:0061630 ubiquitin protein ligase activity; GO:0046914 transition metal ion binding; GO:0019787 ubiquitin-like protein transferase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0004842 ubiquitin-protein transferase activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0061659 ubiquitin-like protein ligase activity; GO:0008270 zinc ion binding; GO:0016740 transferase activity; ","K10307",null,null,"IPR001810; IPR001293; IPR008974; IPR013323; ","\"F-box domain; Zinc finger, TRAF-type; TRAF-like; SIAH-type domain; \"\r"]
["Q8TBC4","NEDD8-activating enzyme E1 catalytic subunit OS=Homo sapiens OX=9606 GN=UBA3","UBA3",51.852,35.846,18.4,6,6,6,0.985,0.997,0.966,1.002,1.049,1.04,1.049,0.0482,"cytoplasm\r","GO:0044700 single organism signaling; GO:0044699 single-organism process; GO:0007113 endomitotic cell cycle; GO:0051253 negative regulation of RNA metabolic process; GO:0044237 cellular metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0051726 regulation of cell cycle; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0010468 regulation of gene expression; GO:0051716 cellular response to stimulus; GO:0000278 mitotic cell cycle; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0070647 protein modification by small protein conjugation or removal; GO:0031323 regulation of cellular metabolic process; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:1902679 negative regulation of RNA biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006464 cellular protein modification process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0036211 protein modification process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0045892 negative regulation of transcription, DNA-templated; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0006508 proteolysis; GO:0009987 cellular process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0038061 NIK/NF-kappaB signaling; GO:0045116 protein neddylation; GO:0006355 regulation of transcription, DNA-templated; GO:0035556 intracellular signal transduction; GO:0010629 negative regulation of gene expression; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0044238 primary metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0009892 negative regulation of metabolic process; GO:0009890 negative regulation of biosynthetic process; GO:0032446 protein modification by small protein conjugation; GO:0031327 negative regulation of cellular biosynthetic process; GO:0043412 macromolecule modification; GO:0007049 cell cycle; GO:0065007 biological regulation; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005829 cytosol; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0005102 receptor binding; GO:0046983 protein dimerization activity; GO:0016874 ligase activity; GO:0005515 protein binding; GO:0016877 ligase activity, forming carbon-sulfur bonds; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0008641 small protein activating enzyme activity; GO:0005524 ATP binding; GO:0046982 protein heterodimerization activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0016881 acid-amino acid ligase activity; GO:0016879 ligase activity, forming carbon-nitrogen bonds; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0019781 NEDD8 activating enzyme activity; GO:0016922 ligand-dependent nuclear receptor binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; ","K10686","UBE1C; ubiquitin-activating enzyme E1 C [EC:6.2.1.45]","hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human); ","IPR000594; IPR023318; IPR016040; IPR014929; ","\"THIF-type NAD/FAD binding fold; Ubiquitin activating enzyme, alpha domain; NAD(P)-binding domain; E2 binding; \"\r"]
["Q8TCE6","Protein FAM45A OS=Homo sapiens OX=9606 GN=FAM45A","FAM45A",40.513,13.269,7,2,2,2,0.95,1.037,1.063,1.043,0.928,0.991,0.971,0.575,"mitochondria\r"]
["Q8TCJ2","Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B OS=Homo sapiens OX=9606 GN=STT3B","STT3B",93.673,15.904,4.1,3,4,3,0.954,0.943,0.995,0.965,1.066,1.076,1.074,0.14,"plasma membrane\r","GO:0043687 post-translational protein modification; GO:0033554 cellular response to stress; GO:0043413 macromolecule glycosylation; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0034976 response to endoplasmic reticulum stress; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0036503 ERAD pathway; GO:0009058 biosynthetic process; GO:0018196 peptidyl-asparagine modification; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0010498 proteasomal protein catabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0035966 response to topologically incorrect protein; GO:0030433 ubiquitin-dependent ERAD pathway; GO:1901137 carbohydrate derivative biosynthetic process; GO:0044248 cellular catabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0006508 proteolysis; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0006487 protein N-linked glycosylation; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0070085 glycosylation; GO:0043632 modification-dependent macromolecule catabolic process; GO:0051716 cellular response to stimulus; GO:0006986 response to unfolded protein; GO:0006486 protein glycosylation; GO:0044265 cellular macromolecule catabolic process; GO:0009101 glycoprotein biosynthetic process; GO:0006516 glycoprotein catabolic process; GO:0006950 response to stress; GO:0019941 modification-dependent protein catabolic process; GO:0044712 single-organism catabolic process; GO:0043686 co-translational protein modification; GO:0044763 single-organism cellular process; GO:1901136 carbohydrate derivative catabolic process; GO:0009100 glycoprotein metabolic process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0018193 peptidyl-amino acid modification; GO:1901575 organic substance catabolic process; GO:0018279 protein N-linked glycosylation via asparagine; GO:0042221 response to chemical; GO:0034645 cellular macromolecule biosynthetic process; GO:0030163 protein catabolic process; GO:0044710 single-organism metabolic process; GO:0009057 macromolecule catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0006464 cellular protein modification process; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:0009056 catabolic process; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0032991 macromolecular complex; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0008250 oligosaccharyltransferase complex; GO:1990234 transferase complex; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:1902494 catalytic complex; GO:0044432 endoplasmic reticulum part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; ","GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity; GO:0016757 transferase activity, transferring glycosyl groups; GO:0016758 transferase activity, transferring hexosyl groups; GO:0003824 catalytic activity; GO:0016740 transferase activity; GO:0004576 oligosaccharyl transferase activity; ","K07151","STT3; dolichyl-diphosphooligosaccharide---protein glycosyltransferase [EC:2.4.99.18]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00510 N-Glycan biosynthesis - Homo sapiens (human); hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); "]
["Q8TD55","Pleckstrin homology domain-containing family O member 2 OS=Homo sapiens OX=9606 GN=PLEKHO2","PLEKHO2",53.349,20.837,11.6,4,4,4,0.979,1.126,0.922,0.941,1.062,0.981,0.986,0.87,"nucleus\r","GO:0045321 leukocyte activation; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0051234 establishment of localization; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0002274 myeloid leukocyte activation; GO:0002443 leukocyte mediated immunity; GO:0016192 vesicle-mediated transport; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0002376 immune system process; GO:0043312 neutrophil degranulation; GO:0002263 cell activation involved in immune response; GO:0002444 myeloid leukocyte mediated immunity; GO:0002366 leukocyte activation involved in immune response; GO:0006810 transport; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0032940 secretion by cell; GO:0001775 cell activation; GO:0043299 leukocyte degranulation; GO:0006955 immune response; GO:0051179 localization; GO:0006887 exocytosis; ","GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ",{"$nulls":4},"IPR011993; IPR001849; ","PH domain-like; Pleckstrin homology domain; \r"]
["Q8TDB6","E3 ubiquitin-protein ligase DTX3L OS=Homo sapiens OX=9606 GN=DTX3L","DTX3L",83.553,10.34,2.8,1,1,1,0.904,0.709,0.649,1.226,1.266,1.225,1.643,0.0366,"nucleus\r","GO:0033554 cellular response to stress; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0006259 DNA metabolic process; GO:0016570 histone modification; GO:0006302 double-strand break repair; GO:0044267 cellular protein metabolic process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0000209 protein polyubiquitination; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0016569 covalent chromatin modification; GO:0009987 cellular process; GO:0010390 histone monoubiquitination; GO:0051716 cellular response to stimulus; GO:0016567 protein ubiquitination; GO:0006950 response to stress; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0016574 histone ubiquitination; GO:0070647 protein modification by small protein conjugation or removal; GO:0044238 primary metabolic process; GO:0006974 cellular response to DNA damage stimulus; GO:0006281 DNA repair; GO:0006513 protein monoubiquitination; GO:0090304 nucleic acid metabolic process; GO:0032446 protein modification by small protein conjugation; GO:0051276 chromosome organization; GO:0006996 organelle organization; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0006325 chromatin organization; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0042393 histone binding; GO:0019787 ubiquitin-like protein transferase activity; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0004842 ubiquitin-protein transferase activity; GO:0043167 ion binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0008270 zinc ion binding; GO:0016740 transferase activity; ","K06058","DTX; deltex [EC:2.3.2.27]","hsa04330 Notch signaling pathway - Homo sapiens (human); ","IPR001841; IPR013083; ","\"Zinc finger, RING-type; Zinc finger, RING/FYVE/PHD-type; \"\r"]
["Q8TDQ7","Glucosamine-6-phosphate isomerase 2 OS=Homo sapiens OX=9606 GN=GNPDA2","GNPDA2",31.084,26.274,38,7,9,4,1.056,1.048,0.989,0.99,0.97,0.975,0.949,0.0735,"cytoplasm\r","GO:1901071 glucosamine-containing compound metabolic process; GO:0044281 small molecule metabolic process; GO:0044699 single-organism process; GO:0044238 primary metabolic process; GO:0005975 carbohydrate metabolic process; GO:0071704 organic substance metabolic process; GO:0006006 glucose metabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0008152 metabolic process; GO:0006044 N-acetylglucosamine metabolic process; GO:0044710 single-organism metabolic process; GO:0005996 monosaccharide metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0006040 amino sugar metabolic process; GO:0019318 hexose metabolic process; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:0016853 isomerase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0019239 deaminase activity; GO:0004342 glucosamine-6-phosphate deaminase activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0016860 intramolecular oxidoreductase activity; GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses; ","K02564","nagB; glucosamine-6-phosphate deaminase [EC:3.5.99.6]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00520 Amino sugar and nucleotide sugar metabolism - Homo sapiens (human); ","IPR006148; ","Glucosamine/galactosamine-6-phosphate isomerase; \r"]
["Q8TDX7","Serine/threonine-protein kinase Nek7 OS=Homo sapiens OX=9606 GN=NEK7","NEK7",34.551,4.891,3.3,1,1,1,0.978,0.951,1.002,1.012,1.055,1.006,1.048,0.09,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0051973 positive regulation of telomerase activity; GO:0009891 positive regulation of biosynthetic process; GO:0044699 single-organism process; GO:1904353 regulation of telomere capping; GO:0032204 regulation of telomere maintenance; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051130 positive regulation of cellular component organization; GO:0008152 metabolic process; GO:0051225 spindle assembly; GO:0022607 cellular component assembly; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0032846 positive regulation of homeostatic process; GO:0044093 positive regulation of molecular function; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0051347 positive regulation of transferase activity; GO:0051726 regulation of cell cycle; GO:0031326 regulation of cellular biosynthetic process; GO:0051054 positive regulation of DNA metabolic process; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0032212 positive regulation of telomere maintenance via telomerase; GO:0031323 regulation of cellular metabolic process; GO:0000226 microtubule cytoskeleton organization; GO:0050789 regulation of biological process; GO:0051052 regulation of DNA metabolic process; GO:0010638 positive regulation of organelle organization; GO:0050790 regulation of catalytic activity; GO:0044260 cellular macromolecule metabolic process; GO:2001252 positive regulation of chromosome organization; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0006464 cellular protein modification process; GO:0051301 cell division; GO:0036211 protein modification process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016310 phosphorylation; GO:0032210 regulation of telomere maintenance via telomerase; GO:0016043 cellular component organization; GO:0007346 regulation of mitotic cell cycle; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0007051 spindle organization; GO:0032844 regulation of homeostatic process; GO:0071704 organic substance metabolic process; GO:1904356 regulation of telomere maintenance via telomere lengthening; GO:0006468 protein phosphorylation; GO:0000910 cytokinesis; GO:0070925 organelle assembly; GO:0009889 regulation of biosynthetic process; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:1904358 positive regulation of telomere maintenance via telomere lengthening; GO:0033043 regulation of organelle organization; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:0007017 microtubule-based process; GO:0048518 positive regulation of biological process; GO:2000278 regulation of DNA biosynthetic process; GO:0033044 regulation of chromosome organization; GO:0043085 positive regulation of catalytic activity; GO:1904355 positive regulation of telomere capping; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0051972 regulation of telomerase activity; GO:0031325 positive regulation of cellular metabolic process; GO:0032206 positive regulation of telomere maintenance; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0022402 cell cycle process; GO:0051128 regulation of cellular component organization; GO:0043412 macromolecule modification; GO:0031328 positive regulation of cellular biosynthetic process; GO:2000573 positive regulation of DNA biosynthetic process; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0005874 microtubule; GO:0005737 cytoplasm; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0005815 microtubule organizing center; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0000922 spindle pole; GO:0099513 polymeric cytoskeletal fiber; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005819 spindle; GO:0099081 supramolecular polymer; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044428 nuclear part; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0004672 protein kinase activity; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016301 kinase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0004674 protein serine/threonine kinase activity; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0016740 transferase activity; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K20876","NEK7; NIMA (never in mitosis gene a)-related kinase 7 [EC:2.7.11.1]","hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human); ","IPR000719; IPR001245; IPR011009; ","Protein kinase domain; Serine-threonine/tyrosine-protein kinase catalytic domain; Protein kinase-like domain; \r"]
["Q8TE77","Protein phosphatase Slingshot homolog 3 OS=Homo sapiens OX=9606 GN=SSH3","SSH3",72.995,10.788,7.3,4,6,4,1.023,1.022,0.99,1.031,0.969,0.977,0.981,0.429,"nucleus\r","GO:0065008 regulation of biological quality; GO:0060491 regulation of cell projection assembly; GO:0048869 cellular developmental process; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0030832 regulation of actin filament length; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0008152 metabolic process; GO:0032535 regulation of cellular component size; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0051493 regulation of cytoskeleton organization; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0048699 generation of neurons; GO:0010591 regulation of lamellipodium assembly; GO:0044763 single-organism cellular process; GO:0032501 multicellular organismal process; GO:0050789 regulation of biological process; GO:0045664 regulation of neuron differentiation; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0010975 regulation of neuron projection development; GO:2000026 regulation of multicellular organismal development; GO:1902903 regulation of supramolecular fiber organization; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0032956 regulation of actin cytoskeleton organization; GO:0044267 cellular protein metabolic process; GO:0031344 regulation of cell projection organization; GO:0044087 regulation of cellular component biogenesis; GO:0051239 regulation of multicellular organismal process; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:1902743 regulation of lamellipodium organization; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0035335 peptidyl-tyrosine dephosphorylation; GO:0048731 system development; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0033043 regulation of organelle organization; GO:0032970 regulation of actin filament-based process; GO:0006470 protein dephosphorylation; GO:0044238 primary metabolic process; GO:0016311 dephosphorylation; GO:0050770 regulation of axonogenesis; GO:0008064 regulation of actin polymerization or depolymerization; GO:0006793 phosphorus metabolic process; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0090066 regulation of anatomical structure size; GO:0051128 regulation of cellular component organization; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:0043412 macromolecule modification; GO:0050793 regulation of developmental process; GO:0022604 regulation of cell morphogenesis; GO:0050767 regulation of neurogenesis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0043231 intracellular membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0043226 organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0043228 non-membrane-bounded organelle; ","GO:0003677 DNA binding; GO:0016791 phosphatase activity; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0004721 phosphoprotein phosphatase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0008092 cytoskeletal protein binding; GO:0042578 phosphoric ester hydrolase activity; GO:0003824 catalytic activity; GO:0004725 protein tyrosine phosphatase activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0003779 actin binding; GO:0008138 protein tyrosine/serine/threonine phosphatase activity; ","K05766","SSH; protein phosphatase slingshot [EC:3.1.3.16 3.1.3.48]","hsa04360 Axon guidance - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); ","IPR029021; IPR000387; IPR009057; IPR000340; IPR020422; IPR014876; ","\"Protein-tyrosine phosphatase-like; Tyrosine specific protein phosphatases domain; Homeobox domain-like; Dual specificity phosphatase, catalytic domain; Dual specificity protein phosphatase domain; DEK, C-terminal; \"\r"]
["Q8TEA7","TBC domain-containing protein kinase-like protein OS=Homo sapiens OX=9606 GN=TBCK","TBCK",100.68,3.4018,1.3,1,1,1,1.052,1.007,0.896,1.124,0.953,0.983,1.036,0.646,"cytoplasm\r","GO:0060627 regulation of vesicle-mediated transport; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0031338 regulation of vesicle fusion; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0030036 actin cytoskeleton organization; GO:0051649 establishment of localization in cell; GO:0010646 regulation of cell communication; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0016049 cell growth; GO:0044763 single-organism cellular process; GO:0006810 transport; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0065009 regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0006464 cellular protein modification process; GO:0036211 protein modification process; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0016310 phosphorylation; GO:0046907 intracellular transport; GO:0044267 cellular protein metabolic process; GO:0071704 organic substance metabolic process; GO:0090630 activation of GTPase activity; GO:0032006 regulation of TOR signaling; GO:0006468 protein phosphorylation; GO:0051345 positive regulation of hydrolase activity; GO:0006886 intracellular protein transport; GO:0007010 cytoskeleton organization; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0009966 regulation of signal transduction; GO:1902531 regulation of intracellular signal transduction; GO:0043547 positive regulation of GTPase activity; GO:0051049 regulation of transport; GO:0033043 regulation of organelle organization; GO:0008283 cell proliferation; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0051641 cellular localization; GO:0043085 positive regulation of catalytic activity; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0051128 regulation of cellular component organization; GO:0043412 macromolecule modification; GO:0051179 localization; GO:0040007 growth; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0030496 midbody; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0005819 spindle; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0043226 organelle; GO:0072686 mitotic spindle; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; ","GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0030695 GTPase regulator activity; GO:0005515 protein binding; GO:0004672 protein kinase activity; GO:0098772 molecular function regulator; GO:0017137 Rab GTPase binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0016301 kinase activity; GO:0017016 Ras GTPase binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0051020 GTPase binding; GO:0016740 transferase activity; GO:0008047 enzyme activator activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0031267 small GTPase binding; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0030234 enzyme regulator activity; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019899 enzyme binding; GO:0005096 GTPase activator activity; GO:0036094 small molecule binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K17544",null,null,"IPR001763; IPR000719; IPR000195; IPR011009; ","Rhodanese-like domain; Protein kinase domain; Rab-GTPase-TBC domain; Protein kinase-like domain; \r"]
["Q8TEX9","Importin-4 OS=Homo sapiens OX=9606 GN=IPO4","IPO4",118.71,87.465,12.9,9,10,9,0.859,0.879,0.835,1.115,1.11,1.159,1.315,1.76E-4,"cyto_nucl\r","GO:0044085 cellular component biogenesis; GO:0016043 cellular component organization; GO:0034728 nucleosome organization; GO:0046907 intracellular transport; GO:0006607 NLS-bearing protein import into nucleus; GO:0072594 establishment of protein localization to organelle; GO:0000060 protein import into nucleus, translocation; GO:0017038 protein import; GO:1902593 single-organism nuclear import; GO:0044699 single-organism process; GO:0051169 nuclear transport; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006323 DNA packaging; GO:0051649 establishment of localization in cell; GO:0034724 DNA replication-independent nucleosome organization; GO:0006334 nucleosome assembly; GO:1902578 single-organism localization; GO:0022607 cellular component assembly; GO:0034723 DNA replication-dependent nucleosome organization; GO:0065003 macromolecular complex assembly; GO:0006335 DNA replication-dependent nucleosome assembly; GO:0006886 intracellular protein transport; GO:0044744 protein targeting to nucleus; GO:1902580 single-organism cellular localization; GO:0033365 protein localization to organelle; GO:0034613 cellular protein localization; GO:0006606 protein import into nucleus; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0006336 DNA replication-independent nucleosome assembly; GO:0009987 cellular process; GO:0031497 chromatin assembly; GO:0071824 protein-DNA complex subunit organization; GO:0071103 DNA conformation change; GO:0044765 single-organism transport; GO:0034622 cellular macromolecular complex assembly; GO:0006333 chromatin assembly or disassembly; GO:0071702 organic substance transport; GO:0006610 ribosomal protein import into nucleus; GO:1902582 single-organism intracellular transport; GO:0043933 macromolecular complex subunit organization; GO:0051641 cellular localization; GO:0065004 protein-DNA complex assembly; GO:0006810 transport; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0051276 chromosome organization; GO:0051170 nuclear import; GO:0006996 organelle organization; GO:0006913 nucleocytoplasmic transport; GO:0006325 chromatin organization; GO:0051179 localization; GO:0034504 protein localization to nucleus; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0031965 nuclear membrane; GO:0070013 intracellular organelle lumen; GO:0044454 nuclear chromosome part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0000790 nuclear chromatin; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005635 nuclear envelope; GO:0043232 intracellular non-membrane-bounded organelle; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0000785 chromatin; GO:0031975 envelope; GO:0000228 nuclear chromosome; GO:0034399 nuclear periphery; GO:0043234 protein complex; GO:0044428 nuclear part; ","GO:0031267 small GTPase binding; GO:0005048 signal sequence binding; GO:0008565 protein transporter activity; GO:0017016 Ras GTPase binding; GO:0042277 peptide binding; GO:0005488 binding; GO:0008139 nuclear localization sequence binding; GO:0022892 substrate-specific transporter activity; GO:0008536 Ran GTPase binding; GO:0005515 protein binding; GO:0033218 amide binding; GO:0051020 GTPase binding; GO:0019899 enzyme binding; GO:0005215 transporter activity; ","K20221",null,null,"IPR001494; IPR034085; IPR011989; IPR016024; ","\"Importin-beta, N-terminal domain; TOG domain; Armadillo-like helical; Armadillo-type fold; \"\r"]
["Q8WU90","Zinc finger CCCH domain-containing protein 15 OS=Homo sapiens OX=9606 GN=ZC3H15","ZC3H15",48.602,8.6335,9.2,3,4,3,0.869,0.904,0.86,1.057,1.25,1.052,1.276,0.0149,"nucleus\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0051716 cellular response to stimulus; GO:0034097 response to cytokine; GO:0007166 cell surface receptor signaling pathway; GO:0071310 cellular response to organic substance; GO:0044699 single-organism process; GO:0010033 response to organic substance; GO:0023052 signaling; GO:0050896 response to stimulus; GO:0071345 cellular response to cytokine stimulus; GO:0007165 signal transduction; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0007154 cell communication; GO:0019221 cytokine-mediated signaling pathway; GO:0009987 cellular process; GO:0070887 cellular response to chemical stimulus; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031974 membrane-enclosed lumen; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0050839 cell adhesion molecule binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0043167 ion binding; GO:0045296 cadherin binding; GO:0003676 nucleic acid binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; ",{"$nulls":3},"IPR000571; IPR032378; ","\"Zinc finger, CCCH-type; ZC3H15/TMA46 family, C-terminal; \"\r"]
["Q8WUM4","Programmed cell death 6-interacting protein OS=Homo sapiens OX=9606 GN=PDCD6IP","PDCD6IP",96.022,211.48,35.5,29,58,29,0.997,0.972,1.021,0.989,1.011,1.025,1.012,0.542,"cytoplasm\r","GO:0060627 regulation of vesicle-mediated transport; GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0010256 endomembrane system organization; GO:0035088 establishment or maintenance of apical/basal cell polarity; GO:0045216 cell-cell junction organization; GO:0051046 regulation of secretion; GO:0044699 single-organism process; GO:0032506 cytokinetic process; GO:0044764 multi-organism cellular process; GO:0000912 assembly of actomyosin apparatus involved in cytokinesis; GO:1902115 regulation of organelle assembly; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0030036 actin cytoskeleton organization; GO:0008152 metabolic process; GO:0022607 cellular component assembly; GO:0032879 regulation of localization; GO:0010824 regulation of centrosome duplication; GO:0006915 apoptotic process; GO:0036258 multivesicular body assembly; GO:0090559 regulation of membrane permeability; GO:0051493 regulation of cytoskeleton organization; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0044419 interspecies interaction between organisms; GO:0051726 regulation of cell cycle; GO:0030011 maintenance of cell polarity; GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity; GO:1903543 positive regulation of exosomal secretion; GO:0031032 actomyosin structure organization; GO:0030866 cortical actin cytoskeleton organization; GO:0045921 positive regulation of exocytosis; GO:0039702 viral budding via host ESCRT complex; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0036257 multivesicular body organization; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0007163 establishment or maintenance of cell polarity; GO:1903530 regulation of secretion by cell; GO:0051704 multi-organism process; GO:0051050 positive regulation of transport; GO:0032886 regulation of microtubule-based process; GO:0044837 actomyosin contractile ring organization; GO:0006810 transport; GO:1902589 single-organism organelle organization; GO:1901575 organic substance catabolic process; GO:0050789 regulation of biological process; GO:1903532 positive regulation of secretion by cell; GO:0010638 positive regulation of organelle organization; GO:1902117 positive regulation of organelle assembly; GO:0030163 protein catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0035090 maintenance of apical/basal cell polarity; GO:0051301 cell division; GO:0045199 maintenance of epithelial cell apical/basal polarity; GO:0051047 positive regulation of secretion; GO:0046605 regulation of centrosome cycle; GO:0050794 regulation of cellular process; GO:0034329 cell junction assembly; GO:0016043 cellular component organization; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0019068 virion assembly; GO:0019058 viral life cycle; GO:0044267 cellular protein metabolic process; GO:0017157 regulation of exocytosis; GO:1902592 multi-organism membrane budding; GO:0044087 regulation of cellular component biogenesis; GO:0000920 cell separation after cytokinesis; GO:0030865 cortical cytoskeleton organization; GO:1903541 regulation of exosomal secretion; GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway; GO:0071704 organic substance metabolic process; GO:0000915 actomyosin contractile ring assembly; GO:0000910 cytokinesis; GO:0070925 organelle assembly; GO:0016032 viral process; GO:0044248 cellular catabolic process; GO:0070830 bicellular tight junction assembly; GO:0006508 proteolysis; GO:0061245 establishment or maintenance of bipolar cell polarity; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:1903553 positive regulation of extracellular exosome assembly; GO:0043297 apical junction assembly; GO:0007043 cell-cell junction assembly; GO:0070507 regulation of microtubule cytoskeleton organization; GO:0044265 cellular macromolecule catabolic process; GO:1903551 regulation of extracellular exosome assembly; GO:0044803 multi-organism membrane organization; GO:0051049 regulation of transport; GO:0016192 vesicle-mediated transport; GO:0016050 vesicle organization; GO:0033043 regulation of organelle organization; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:1902590 multi-organism organelle organization; GO:0048518 positive regulation of biological process; GO:0045184 establishment of protein localization; GO:0034330 cell junction organization; GO:0061640 cytoskeleton-dependent cytokinesis; GO:0046755 viral budding; GO:0008219 cell death; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0006900 membrane budding; GO:0009057 macromolecule catabolic process; GO:0030029 actin filament-based process; GO:0012501 programmed cell death; GO:0051128 regulation of cellular component organization; GO:0022402 cell cycle process; GO:0051179 localization; GO:0007032 endosome organization; GO:0009056 catabolic process; GO:0044089 positive regulation of cellular component biogenesis; GO:0007049 cell cycle; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0048770 pigment granule; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0005815 microtubule organizing center; GO:0005925 focal adhesion; GO:0015630 microtubule cytoskeleton; GO:0044425 membrane part; GO:0043209 myelin sheath; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0042641 actomyosin; GO:0005924 cell-substrate adherens junction; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0042470 melanosome; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0015629 actin cytoskeleton; GO:0005886 plasma membrane; GO:0070971 endoplasmic reticulum exit site; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0044432 endoplasmic reticulum part; GO:0001772 immunological synapse; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0042802 identical protein binding; GO:0005102 receptor binding; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:0001664 G-protein coupled receptor binding; GO:0048306 calcium-dependent protein binding; GO:0031871 proteinase activated receptor binding; ","K12200","PDCD6IP; programmed cell death 6-interacting protein","hsa04144 Endocytosis - Homo sapiens (human); ","IPR025304; IPR004328; ","ALIX V-shaped domain; BRO1 domain; \r"]
["Q8WUW1","Protein BRICK1 OS=Homo sapiens OX=9606 GN=BRK1","BRK1",8.7448,21.572,54.7,4,8,4,0.93,0.91,0.925,1.086,1.038,1.084,1.16,0.000779,"cytoplasm\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0030833 regulation of actin filament polymerization; GO:0065008 regulation of biological quality; GO:0051674 localization of cell; GO:0007166 cell surface receptor signaling pathway; GO:0060491 regulation of cell projection assembly; GO:0043009 chordate embryonic development; GO:0038094 Fc-gamma receptor signaling pathway; GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation; GO:0044699 single-organism process; GO:0030832 regulation of actin filament length; GO:0051234 establishment of localization; GO:0006909 phagocytosis; GO:0051130 positive regulation of cellular component organization; GO:0007165 signal transduction; GO:0030036 actin cytoskeleton organization; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0032535 regulation of cellular component size; GO:0032271 regulation of protein polymerization; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0051493 regulation of cytoskeleton organization; GO:0009790 embryo development; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0044765 single-organism transport; GO:0032502 developmental process; GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis; GO:0051716 cellular response to stimulus; GO:0071822 protein complex subunit organization; GO:0031346 positive regulation of cell projection organization; GO:0010591 regulation of lamellipodium assembly; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0048522 positive regulation of cellular process; GO:0007264 small GTPase mediated signal transduction; GO:0048870 cell motility; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0050776 regulation of immune response; GO:0006810 transport; GO:1902745 positive regulation of lamellipodium organization; GO:1902589 single-organism organelle organization; GO:0043254 regulation of protein complex assembly; GO:0050789 regulation of biological process; GO:0001701 in utero embryonic development; GO:0010638 positive regulation of organelle organization; GO:0048583 regulation of response to stimulus; GO:0016601 Rac protein signal transduction; GO:0002682 regulation of immune system process; GO:1902905 positive regulation of supramolecular fiber organization; GO:0002431 Fc receptor mediated stimulatory signaling pathway; GO:0040011 locomotion; GO:0048010 vascular endothelial growth factor receptor signaling pathway; GO:0070271 protein complex biogenesis; GO:0048856 anatomical structure development; GO:0097435 supramolecular fiber organization; GO:0007265 Ras protein signal transduction; GO:1902903 regulation of supramolecular fiber organization; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0042127 regulation of cell proliferation; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0002252 immune effector process; GO:0051260 protein homooligomerization; GO:0032956 regulation of actin cytoskeleton organization; GO:0007015 actin filament organization; GO:0031344 regulation of cell projection organization; GO:0044087 regulation of cellular component biogenesis; GO:0050896 response to stimulus; GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation; GO:0051259 protein oligomerization; GO:1902578 single-organism localization; GO:1902743 regulation of lamellipodium organization; GO:0002757 immune response-activating signal transduction; GO:0010592 positive regulation of lamellipodium assembly; GO:0007275 multicellular organism development; GO:0038093 Fc receptor signaling pathway; GO:0007010 cytoskeleton organization; GO:0050778 positive regulation of immune response; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0002253 activation of immune response; GO:0070206 protein trimerization; GO:0051495 positive regulation of cytoskeleton organization; GO:0035556 intracellular signal transduction; GO:0051125 regulation of actin nucleation; GO:0016192 vesicle-mediated transport; GO:0009792 embryo development ending in birth or egg hatching; GO:0033043 regulation of organelle organization; GO:0002376 immune system process; GO:0032970 regulation of actin filament-based process; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0043933 macromolecular complex subunit organization; GO:0070207 protein homotrimerization; GO:0008064 regulation of actin polymerization or depolymerization; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0002684 positive regulation of immune system process; GO:0030029 actin filament-based process; GO:0006928 movement of cell or subcellular component; GO:0090066 regulation of anatomical structure size; GO:0051128 regulation of cellular component organization; GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0044089 positive regulation of cellular component biogenesis; GO:0051127 positive regulation of actin nucleation; GO:0008284 positive regulation of cell proliferation; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0031252 cell leading edge; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0044421 extracellular region part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043228 non-membrane-bounded organelle; GO:0031209 SCAR complex; GO:0005856 cytoskeleton; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:0030027 lamellipodium; GO:1903561 extracellular vesicle; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; GO:0032403 protein complex binding; GO:0044877 macromolecular complex binding; ","K05752","C3ORF10; chromosome 3 open reading frame 10","hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); "]
["Q8WVM8","Sec1 family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCFD1","SCFD1",72.379,63.525,26,12,14,12,0.997,0.964,1.064,0.985,1.021,1.026,1.002,0.929,"plasma membrane\r","GO:0060627 regulation of vesicle-mediated transport; GO:0044085 cellular component biogenesis; GO:0006901 vesicle coating; GO:0048207 vesicle targeting, rough ER to cis-Golgi; GO:1902902 negative regulation of autophagosome assembly; GO:0048208 COPII vesicle coating; GO:0048869 cellular developmental process; GO:0051129 negative regulation of cellular component organization; GO:0032989 cellular component morphogenesis; GO:0044699 single-organism process; GO:1901998 toxin transport; GO:1902116 negative regulation of organelle assembly; GO:1902115 regulation of organelle assembly; GO:0015031 protein transport; GO:0006909 phagocytosis; GO:0051234 establishment of localization; GO:0051649 establishment of localization in cell; GO:0022607 cellular component assembly; GO:0032879 regulation of localization; GO:0065003 macromolecular complex assembly; GO:0060628 regulation of ER to Golgi vesicle-mediated transport; GO:0048199 vesicle targeting, to, from or within Golgi; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0032502 developmental process; GO:0051650 establishment of vesicle localization; GO:0044088 regulation of vacuole organization; GO:0071822 protein complex subunit organization; GO:0006904 vesicle docking involved in exocytosis; GO:0031329 regulation of cellular catabolic process; GO:0009636 response to toxic substance; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0032386 regulation of intracellular transport; GO:0031323 regulation of cellular metabolic process; GO:0010506 regulation of autophagy; GO:0000902 cell morphogenesis; GO:0006810 transport; GO:0016241 regulation of macroautophagy; GO:2000785 regulation of autophagosome assembly; GO:0010639 negative regulation of organelle organization; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032940 secretion by cell; GO:0019222 regulation of metabolic process; GO:0051223 regulation of protein transport; GO:0010507 negative regulation of autophagy; GO:0070271 protein complex biogenesis; GO:0048856 anatomical structure development; GO:0016242 negative regulation of macroautophagy; GO:0050794 regulation of cellular process; GO:0051640 organelle localization; GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0009628 response to abiotic stimulus; GO:0048193 Golgi vesicle transport; GO:0044087 regulation of cellular component biogenesis; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0006903 vesicle targeting; GO:0050896 response to stimulus; GO:0022406 membrane docking; GO:0070201 regulation of establishment of protein localization; GO:0060341 regulation of cellular localization; GO:0009653 anatomical structure morphogenesis; GO:1902578 single-organism localization; GO:0001666 response to hypoxia; GO:0051648 vesicle localization; GO:0070482 response to oxygen levels; GO:0009895 negative regulation of catabolic process; GO:0032880 regulation of protein localization; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0006950 response to stress; GO:0090114 COPII-coated vesicle budding; GO:0051049 regulation of transport; GO:0016192 vesicle-mediated transport; GO:0033043 regulation of organelle organization; GO:0016050 vesicle organization; GO:0071702 organic substance transport; GO:0006897 endocytosis; GO:0051656 establishment of organelle localization; GO:0048278 vesicle docking; GO:0009892 negative regulation of metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0031330 negative regulation of cellular catabolic process; GO:0006890 retrograde vesicle-mediated transport, Golgi to ER; GO:0044767 single-organism developmental process; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0006900 membrane budding; GO:0036293 response to decreased oxygen levels; GO:0051128 regulation of cellular component organization; GO:0006892 post-Golgi vesicle-mediated transport; GO:0051179 localization; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0006887 exocytosis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005801 cis-Golgi network; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098791 Golgi subcompartment; GO:0044431 Golgi apparatus part; GO:0017119 Golgi transport complex; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0099023 tethering complex; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0032580 Golgi cisterna membrane; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0005795 Golgi stack; GO:0005829 cytosol; GO:0005798 Golgi-associated vesicle; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044432 endoplasmic reticulum part; GO:0043234 protein complex; GO:0005794 Golgi apparatus; GO:0031985 Golgi cisterna; GO:0044444 cytoplasmic part; GO:0031984 organelle subcompartment; ","GO:0000149 SNARE binding; GO:0005515 protein binding; GO:0047485 protein N-terminus binding; GO:0019905 syntaxin binding; GO:0005488 binding; ","K19998",null,null,"IPR027482; ","\"Sec1-like, domain 2; \"\r"]
["Q8WVV4","Protein POF1B OS=Homo sapiens OX=9606 GN=POF1B","POF1B",68.064,45.51,15.4,8,10,8,0.92,0.88,0.819,1.088,1.125,1.053,1.247,0.0047,"cyto_nucl\r",null,"GO:0070160 occluding junction; GO:0030054 cell junction; GO:0070161 anchoring junction; GO:0005911 cell-cell junction; GO:0005923 bicellular tight junction; GO:0043296 apical junction complex; GO:0030057 desmosome; ","GO:0003779 actin binding; GO:0005515 protein binding; GO:0008092 cytoskeletal protein binding; GO:0005488 binding; "]
["Q8WVY7","Ubiquitin-like domain-containing CTD phosphatase 1 OS=Homo sapiens OX=9606 GN=UBLCP1","UBLCP1",36.804,8.274,8.8,3,4,3,0.988,0.923,0.926,1.035,1.126,1.032,1.125,0.0311,"cytoplasm\r","GO:0044267 cellular protein metabolic process; GO:0044238 primary metabolic process; GO:0006470 protein dephosphorylation; GO:0016311 dephosphorylation; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0006793 phosphorus metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:0009987 cellular process; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005730 nucleolus; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031974 membrane-enclosed lumen; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0042578 phosphoric ester hydrolase activity; GO:0003824 catalytic activity; GO:0004722 protein serine/threonine phosphatase activity; GO:0016791 phosphatase activity; GO:0005488 binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0004721 phosphoprotein phosphatase activity; ","K17618",null,null,"IPR029071; IPR000626; IPR004274; IPR011943; IPR023214; ","\"Ubiquitin-related domain; Ubiquitin domain; FCP1 homology domain; HAD-superfamily hydrolase, subfamily IIID; HAD-like domain; \"\r"]
["Q8WWC4","m-AAA protease-interacting protein 1, mitochondrial OS=Homo sapiens OX=9606 GN=MAIP1","MAIP1",32.544,3.3436,5.2,2,2,2,1.012,0.769,1.288,1.01,0.847,1.076,0.956,0.872,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0072594 establishment of protein localization to organelle; GO:0072503 cellular divalent inorganic cation homeostasis; GO:0006839 mitochondrial transport; GO:0044699 single-organism process; GO:0051234 establishment of localization; GO:0051649 establishment of localization in cell; GO:0097034 mitochondrial respiratory chain complex IV biogenesis; GO:0007005 mitochondrion organization; GO:0055065 metal ion homeostasis; GO:0033365 protein localization to organelle; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0060401 cytosolic calcium ion transport; GO:0098655 cation transmembrane transport; GO:0072657 protein localization to membrane; GO:0050801 ion homeostasis; GO:0055074 calcium ion homeostasis; GO:0098771 inorganic ion homeostasis; GO:0044763 single-organism cellular process; GO:0019725 cellular homeostasis; GO:0006874 cellular calcium ion homeostasis; GO:0007007 inner mitochondrial membrane organization; GO:0006810 transport; GO:0006851 mitochondrial calcium ion transport; GO:1902589 single-organism organelle organization; GO:0032978 protein insertion into membrane from inner side; GO:0070509 calcium ion import; GO:0070271 protein complex biogenesis; GO:0072655 establishment of protein localization to mitochondrion; GO:0072507 divalent inorganic cation homeostasis; GO:0098662 inorganic cation transmembrane transport; GO:0016043 cellular component organization; GO:0034220 ion transmembrane transport; GO:0072511 divalent inorganic cation transport; GO:0007006 mitochondrial membrane organization; GO:0030001 metal ion transport; GO:0030003 cellular cation homeostasis; GO:0055082 cellular chemical homeostasis; GO:0042592 homeostatic process; GO:0036444 mitochondrial calcium uptake; GO:1902578 single-organism localization; GO:0006812 cation transport; GO:0006816 calcium ion transport; GO:0055080 cation homeostasis; GO:1990542 mitochondrial transmembrane transport; GO:1902580 single-organism cellular localization; GO:0034613 cellular protein localization; GO:0090150 establishment of protein localization to membrane; GO:0009987 cellular process; GO:0051205 protein insertion into membrane; GO:0048878 chemical homeostasis; GO:0070588 calcium ion transmembrane transport; GO:0098660 inorganic ion transmembrane transport; GO:0044802 single-organism membrane organization; GO:0051560 mitochondrial calcium ion homeostasis; GO:0032979 protein insertion into mitochondrial membrane from inner side; GO:0051204 protein insertion into mitochondrial membrane; GO:0070585 protein localization to mitochondrion; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0055085 transmembrane transport; GO:0070727 cellular macromolecule localization; GO:0006873 cellular ion homeostasis; GO:0006811 ion transport; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0006875 cellular metal ion homeostasis; GO:0051179 localization; GO:0097033 mitochondrial respiratory chain complex III biogenesis; GO:0071840 cellular component organization or biogenesis; GO:0070838 divalent metal ion transport; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0031090 organelle membrane; GO:0031967 organelle envelope; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0031975 envelope; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0043022 ribosome binding; GO:0005515 protein binding; GO:0005488 binding; GO:0043021 ribonucleoprotein complex binding; GO:0044877 macromolecular complex binding; "]
["Q8WWP7","GTPase IMAP family member 1 OS=Homo sapiens OX=9606 GN=GIMAP1","GIMAP1",34.369,8.2378,9.8,3,3,3,1.132,0.96,0.938,1.005,1.017,0.96,0.984,0.847,"cytoplasm\r",null,"GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0098588 bounding membrane of organelle; GO:0031090 organelle membrane; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0000139 Golgi membrane; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044432 endoplasmic reticulum part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0044431 Golgi apparatus part; GO:0043227 membrane-bounded organelle; GO:0005794 Golgi apparatus; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0000166 nucleotide binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0036094 small molecule binding; ",{"$nulls":3},"IPR006703; IPR027417; ","AIG1-type guanine nucleotide-binding (G) domain; P-loop containing nucleoside triphosphate hydrolase; \r"]
["Q8WX92","Negative elongation factor B OS=Homo sapiens OX=9606 GN=NELFB","NELFB",65.697,9.9417,6,4,5,4,0.939,1.04,0.751,1.105,1.021,1.147,1.199,0.137,"nucleus\r","GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter; GO:0097659 nucleic acid-templated transcription; GO:0009891 positive regulation of biosynthetic process; GO:0009058 biosynthetic process; GO:0006354 DNA-templated transcription, elongation; GO:0044237 cellular metabolic process; GO:0051253 negative regulation of RNA metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0032784 regulation of DNA-templated transcription, elongation; GO:0043170 macromolecule metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:1903902 positive regulation of viral life cycle; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0043902 positive regulation of multi-organism process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0000122 negative regulation of transcription from RNA polymerase II promoter; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0050434 positive regulation of viral transcription; GO:0006351 transcription, DNA-templated; GO:1902679 negative regulation of RNA biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0006725 cellular aromatic compound metabolic process; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0048523 negative regulation of cellular process; GO:0071704 organic substance metabolic process; GO:0045892 negative regulation of transcription, DNA-templated; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0051254 positive regulation of RNA metabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0043900 regulation of multi-organism process; GO:0006368 transcription elongation from RNA polymerase II promoter; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0050792 regulation of viral process; GO:0006807 nitrogen compound metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0034243 regulation of transcription elongation from RNA polymerase II promoter; GO:0009890 negative regulation of biosynthetic process; GO:0046782 regulation of viral transcription; GO:0032785 negative regulation of DNA-templated transcription, elongation; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0048524 positive regulation of viral process; GO:0006366 transcription from RNA polymerase II promoter; GO:0031325 positive regulation of cellular metabolic process; GO:0010467 gene expression; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0031327 negative regulation of cellular biosynthetic process; GO:1903900 regulation of viral life cycle; GO:0031328 positive regulation of cellular biosynthetic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0032021 NELF complex; GO:0008023 transcription elongation factor complex; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005515 protein binding; GO:0005488 binding; GO:0003676 nucleic acid binding; ","K15180"]
["Q8WXF7","Atlastin-1 OS=Homo sapiens OX=9606 GN=ATL1","ATL1",63.543,11.124,8.2,4,5,3,1.089,1.217,1.082,0.895,0.915,0.831,0.78,6.62E-3,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0010256 endomembrane system organization; GO:0051260 protein homooligomerization; GO:0048869 cellular developmental process; GO:0048666 neuron development; GO:0044699 single-organism process; GO:0032989 cellular component morphogenesis; GO:0022008 neurogenesis; GO:0048468 cell development; GO:0000904 cell morphogenesis involved in differentiation; GO:0051259 protein oligomerization; GO:0009653 anatomical structure morphogenesis; GO:0030154 cell differentiation; GO:0032990 cell part morphogenesis; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0007409 axonogenesis; GO:0048858 cell projection morphogenesis; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0071822 protein complex subunit organization; GO:0048699 generation of neurons; GO:0048731 system development; GO:0044763 single-organism cellular process; GO:0048812 neuron projection morphogenesis; GO:0031175 neuron projection development; GO:0032501 multicellular organismal process; GO:0043933 macromolecular complex subunit organization; GO:0000902 cell morphogenesis; GO:0030182 neuron differentiation; GO:0061564 axon development; GO:0030030 cell projection organization; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0070271 protein complex biogenesis; GO:0048856 anatomical structure development; GO:0007029 endoplasmic reticulum organization; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0098827 endoplasmic reticulum subcompartment; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0098791 Golgi subcompartment; GO:0043005 neuron projection; GO:0044431 Golgi apparatus part; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0005789 endoplasmic reticulum membrane; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0005795 Golgi stack; GO:0012505 endomembrane system; GO:0016021 integral component of membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0071782 endoplasmic reticulum tubular network; GO:0030424 axon; GO:0044432 endoplasmic reticulum part; GO:0005794 Golgi apparatus; GO:0000137 Golgi cis cisterna; GO:0031985 Golgi cisterna; GO:0044444 cytoplasmic part; GO:0031984 organelle subcompartment; ","GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0042802 identical protein binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0003924 GTPase activity; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019001 guanyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0036094 small molecule binding; ","K17339",null,null,"IPR015894; IPR027417; IPR030386; IPR003191; ","\"Guanylate-binding protein, N-terminal; P-loop containing nucleoside triphosphate hydrolase; GB1/RHD3-type guanine nucleotide-binding (G) domain; Guanylate-binding protein, C-terminal; \"\r"]
["Q8WXI9","Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B","GATAD2B",65.26,8.9309,5.7,2,2,2,0.973,1.069,0.991,0.986,0.983,1.009,0.982,0.59,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0006338 chromatin remodeling; GO:0006725 cellular aromatic compound metabolic process; GO:0097659 nucleic acid-templated transcription; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0006355 regulation of transcription, DNA-templated; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0032774 RNA biosynthetic process; GO:0043044 ATP-dependent chromatin remodeling; GO:0031323 regulation of cellular metabolic process; GO:0044238 primary metabolic process; GO:0051252 regulation of RNA metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0051276 chromosome organization; GO:0034645 cellular macromolecule biosynthetic process; GO:0090304 nucleic acid metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006351 transcription, DNA-templated; GO:0006996 organelle organization; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0010467 gene expression; GO:0006325 chromatin organization; GO:1901362 organic cyclic compound biosynthetic process; GO:0071840 cellular component organization or biogenesis; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0000785 chromatin; GO:0044454 nuclear chromosome part; GO:0016607 nuclear speck; GO:0044464 cell part; GO:0005622 intracellular; GO:0005694 chromosome; GO:0000790 nuclear chromatin; GO:0000228 nuclear chromosome; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003677 DNA binding; GO:0046914 transition metal ion binding; GO:0005488 binding; GO:0001071 nucleic acid binding transcription factor activity; GO:0003676 nucleic acid binding; GO:0043167 ion binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0008270 zinc ion binding; GO:0043565 sequence-specific DNA binding; GO:0003700 transcription factor activity, sequence-specific DNA binding; ",{"$nulls":3},"IPR013088; IPR032346; IPR000679; ","\"Zinc finger, NHR/GATA-type; Transcriptional repressor p66, coiled-coil MBD2-interaction domain; Zinc finger, GATA-type; \"\r"]
["Q8WY22","BRI3-binding protein OS=Homo sapiens OX=9606 GN=BRI3BP","BRI3BP",27.835,28.217,17.1,3,3,3,1.118,1.068,1.217,0.823,0.913,0.881,0.769,0.00584,"extracellular\r",null,"GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0019867 outer membrane; GO:0044429 mitochondrial part; GO:0098588 bounding membrane of organelle; GO:0031090 organelle membrane; GO:0005741 mitochondrial outer membrane; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005740 mitochondrial envelope; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0031975 envelope; GO:0098805 whole membrane; GO:0031968 organelle outer membrane; GO:0043227 membrane-bounded organelle; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; "]
["Q8WZ42","Titin OS=Homo sapiens OX=9606 GN=TTN","TTN",3816,148.85,0.5,13,17,13,0.743,0.694,1.194,1.157,1.044,1.136,1.268,0.199,null,"GO:0044085 cellular component biogenesis; GO:0060415 muscle tissue morphogenesis; GO:0018212 peptidyl-tyrosine modification; GO:0032989 cellular component morphogenesis; GO:0044237 cellular metabolic process; GO:0009605 response to external stimulus; GO:0030036 actin cytoskeleton organization; GO:0008152 metabolic process; GO:0007507 heart development; GO:0065003 macromolecular complex assembly; GO:0051606 detection of stimulus; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0055013 cardiac muscle cell development; GO:0030240 skeletal muscle thin filament assembly; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0000278 mitotic cell cycle; GO:0042325 regulation of phosphorylation; GO:0007059 chromosome segregation; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:0060537 muscle tissue development; GO:0055008 cardiac muscle tissue morphogenesis; GO:0044763 single-organism cellular process; GO:0006941 striated muscle contraction; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:0048513 animal organ development; GO:0055002 striated muscle cell development; GO:0050790 regulation of catalytic activity; GO:0048644 muscle organ morphogenesis; GO:0044260 cellular macromolecule metabolic process; GO:0009887 animal organ morphogenesis; GO:0006464 cellular protein modification process; GO:0003015 heart process; GO:0050982 detection of mechanical stimulus; GO:0003013 circulatory system process; GO:0097435 supramolecular fiber organization; GO:0014897 striated muscle hypertrophy; GO:0050794 regulation of cellular process; GO:0072359 circulatory system development; GO:0055001 muscle cell development; GO:0016310 phosphorylation; GO:0044707 single-multicellular organism process; GO:0030049 muscle filament sliding; GO:0055006 cardiac cell development; GO:0048739 cardiac muscle fiber development; GO:0009581 detection of external stimulus; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0002576 platelet degranulation; GO:1903047 mitotic cell cycle process; GO:0035994 response to muscle stretch; GO:0030261 chromosome condensation; GO:0009653 anatomical structure morphogenesis; GO:0055007 cardiac muscle cell differentiation; GO:0006323 DNA packaging; GO:1902578 single-organism localization; GO:0030239 myofibril assembly; GO:0051338 regulation of transferase activity; GO:0061061 muscle structure development; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0006461 protein complex assembly; GO:0035051 cardiocyte differentiation; GO:0048731 system development; GO:0009582 detection of abiotic stimulus; GO:0007076 mitotic chromosome condensation; GO:0016192 vesicle-mediated transport; GO:0010927 cellular component assembly involved in morphogenesis; GO:0044238 primary metabolic process; GO:0045055 regulated exocytosis; GO:0051276 chromosome organization; GO:0006793 phosphorus metabolic process; GO:0098813 nuclear chromosome segregation; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0000280 nuclear division; GO:0006928 movement of cell or subcellular component; GO:0043412 macromolecule modification; GO:0051179 localization; GO:0006887 exocytosis; GO:0030048 actin filament-based movement; GO:0003012 muscle system process; GO:0070252 actin-mediated cell contraction; GO:0048747 muscle fiber development; GO:0007067 mitotic nuclear division; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0000819 sister chromatid segregation; GO:0048729 tissue morphogenesis; GO:0022607 cellular component assembly; GO:0010035 response to inorganic substance; GO:0071688 striated muscle myosin thick filament assembly; GO:0071103 DNA conformation change; GO:0055003 cardiac myofibril assembly; GO:0032502 developmental process; GO:0030241 skeletal muscle myosin thick filament assembly; GO:0031032 actomyosin structure organization; GO:0009888 tissue development; GO:0071822 protein complex subunit organization; GO:0003007 heart morphogenesis; GO:0031033 myosin filament organization; GO:0048769 sarcomerogenesis; GO:0031034 myosin filament assembly; GO:0010038 response to metal ion; GO:0018108 peptidyl-tyrosine phosphorylation; GO:1902589 single-organism organelle organization; GO:0045214 sarcomere organization; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0042221 response to chemical; GO:0014896 muscle hypertrophy; GO:0007517 muscle organ development; GO:0032940 secretion by cell; GO:0014866 skeletal myofibril assembly; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0070271 protein complex biogenesis; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0043549 regulation of kinase activity; GO:0014706 striated muscle tissue development; GO:0045859 regulation of protein kinase activity; GO:0016043 cellular component organization; GO:0048738 cardiac muscle tissue development; GO:0060255 regulation of macromolecule metabolic process; GO:0048285 organelle fission; GO:0007015 actin filament organization; GO:0060048 cardiac muscle contraction; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0071704 organic substance metabolic process; GO:0009612 response to mechanical stimulus; GO:0030154 cell differentiation; GO:0006936 muscle contraction; GO:0006468 protein phosphorylation; GO:0070925 organelle assembly; GO:0003300 cardiac muscle hypertrophy; GO:0008015 blood circulation; GO:0051592 response to calcium ion; GO:0060047 heart contraction; GO:0009987 cellular process; GO:0043623 cellular protein complex assembly; GO:0051146 striated muscle cell differentiation; GO:0034622 cellular macromolecular complex assembly; GO:0003008 system process; GO:0033275 actin-myosin filament sliding; GO:0001932 regulation of protein phosphorylation; GO:0000070 mitotic sister chromatid segregation; GO:0035995 detection of muscle stretch; GO:0043933 macromolecular complex subunit organization; GO:0018193 peptidyl-amino acid modification; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0042692 muscle cell differentiation; GO:0022402 cell cycle process; GO:0007049 cell cycle; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0044421 extracellular region part; GO:0030016 myofibril; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0030018 Z disc; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0031674 I band; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0000793 condensed chromosome; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0016460 myosin II complex; GO:1903561 extracellular vesicle; GO:0043292 contractile fiber; GO:0005865 striated muscle thin filament; GO:0031430 M band; GO:0016459 myosin complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005859 muscle myosin complex; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0015629 actin cytoskeleton; GO:0036379 myofilament; GO:0099081 supramolecular polymer; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0031672 A band; GO:0030017 sarcomere; GO:0000228 nuclear chromosome; GO:0044449 contractile fiber part; GO:0000794 condensed nuclear chromosome; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0051015 actin filament binding; GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0043621 protein self-association; GO:0019901 protein kinase binding; GO:0004713 protein tyrosine kinase activity; GO:0005515 protein binding; GO:0004672 protein kinase activity; GO:0008307 structural constituent of muscle; GO:0097493 structural molecule activity conferring elasticity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0042802 identical protein binding; GO:0008092 cytoskeletal protein binding; GO:0016301 kinase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0042805 actinin binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0031433 telethonin binding; GO:0005524 ATP binding; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0019900 kinase binding; GO:0005516 calmodulin binding; GO:0051371 muscle alpha-actinin binding; GO:0002020 protease binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003779 actin binding; GO:0046872 metal ion binding; GO:0004674 protein serine/threonine kinase activity; GO:0032555 purine ribonucleotide binding; GO:0005509 calcium ion binding; GO:0051393 alpha-actinin binding; GO:0001883 purine nucleoside binding; GO:0005198 structural molecule activity; GO:0019899 enzyme binding; GO:0036094 small molecule binding; GO:0032403 protein complex binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K12567","TTN; titin [EC:2.7.11.1]","hsa05414 Dilated cardiomyopathy (DCM) - Homo sapiens (human); hsa05410 Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human); ","IPR003598; IPR007110; IPR000719; IPR013783; IPR003599; IPR013106; IPR003961; IPR013098; IPR011009; ","Immunoglobulin subtype 2; Immunoglobulin-like domain; Protein kinase domain; Immunoglobulin-like fold; Immunoglobulin subtype; Immunoglobulin V-set domain; Fibronectin type III; Immunoglobulin I-set; Protein kinase-like domain; \r"]
["Q8WZA9","Immunity-related GTPase family Q protein OS=Homo sapiens OX=9606 GN=IRGQ","IRGQ",62.717,9.5488,4.5,2,3,2,1.105,0.911,0.941,1.097,0.97,0.987,1.033,0.653,"cyto_nucl\r",null,null,"GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0032561 guanyl ribonucleotide binding; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ",{"$nulls":3},"IPR030385; ","IRG-type guanine nucleotide-binding (G) domain; \r"]
["Q92499","ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1","DDX1",82.431,119.27,31.6,20,25,20,0.997,0.993,0.982,0.987,1.054,0.971,1.013,0.643,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:1903608 protein localization to cytoplasmic stress granule; GO:0022618 ribonucleoprotein complex assembly; GO:0010608 posttranscriptional regulation of gene expression; GO:0097659 nucleic acid-templated transcription; GO:0032392 DNA geometric change; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0009607 response to biotic stimulus; GO:0009605 response to external stimulus; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0071826 ribonucleoprotein complex subunit organization; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0043170 macromolecule metabolic process; GO:0033365 protein localization to organelle; GO:0044419 interspecies interaction between organisms; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0071103 DNA conformation change; GO:0034470 ncRNA processing; GO:0006396 RNA processing; GO:0032502 developmental process; GO:0014070 response to organic cyclic compound; GO:0010468 regulation of gene expression; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0043331 response to dsRNA; GO:1901360 organic cyclic compound metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0032268 regulation of cellular protein metabolic process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0008033 tRNA processing; GO:1901698 response to nitrogen compound; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0090305 nucleic acid phosphodiester bond hydrolysis; GO:0016071 mRNA metabolic process; GO:0048856 anatomical structure development; GO:0009615 response to virus; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0033554 cellular response to stress; GO:0044707 single-multicellular organism process; GO:0006725 cellular aromatic compound metabolic process; GO:0006259 DNA metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0006302 double-strand break repair; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0016032 viral process; GO:0009889 regulation of biosynthetic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0009059 macromolecule biosynthetic process; GO:0034613 cellular protein localization; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0010501 RNA secondary structure unwinding; GO:0034622 cellular macromolecular complex assembly; GO:0006355 regulation of transcription, DNA-templated; GO:0006950 response to stress; GO:0043330 response to exogenous dsRNA; GO:0032508 DNA duplex unwinding; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0006974 cellular response to DNA damage stimulus; GO:0043933 macromolecular complex subunit organization; GO:0034248 regulation of cellular amide metabolic process; GO:0051641 cellular localization; GO:0000394 RNA splicing, via endonucleolytic cleavage and ligation; GO:0006281 DNA repair; GO:0070727 cellular macromolecule localization; GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation; GO:0006399 tRNA metabolic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0051276 chromosome organization; GO:0051246 regulation of protein metabolic process; GO:0006417 regulation of translation; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0006446 regulation of translational initiation; GO:0010467 gene expression; GO:0051179 localization; GO:0000245 spliceosomal complex assembly; GO:0034660 ncRNA metabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0072669 tRNA-splicing ligase complex; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0010494 cytoplasmic stress granule; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0071920 cleavage body; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0035770 ribonucleoprotein granule; GO:1990904 ribonucleoprotein complex; GO:0043234 protein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0008026 ATP-dependent helicase activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0003682 chromatin binding; GO:0016887 ATPase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0043168 anion binding; GO:0004004 ATP-dependent RNA helicase activity; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0008143 poly(A) binding; GO:0003723 RNA binding; GO:0003677 DNA binding; GO:0070035 purine NTP-dependent helicase activity; GO:0005524 ATP binding; GO:0004386 helicase activity; GO:0003725 double-stranded RNA binding; GO:0008186 RNA-dependent ATPase activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0070717 poly-purine tract binding; GO:0000166 nucleotide binding; GO:0003712 transcription cofactor activity; GO:0017111 nucleoside-triphosphatase activity; GO:0003727 single-stranded RNA binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003724 RNA helicase activity; GO:0004518 nuclease activity; GO:0016788 hydrolase activity, acting on ester bonds; GO:0042623 ATPase activity, coupled; GO:0003676 nucleic acid binding; GO:0004527 exonuclease activity; GO:0032555 purine ribonucleotide binding; GO:0033677 DNA/RNA helicase activity; GO:0001883 purine nucleoside binding; GO:0000988 transcription factor activity, protein binding; GO:0036094 small molecule binding; ","K13177",null,null,"IPR011545; IPR014014; IPR001870; IPR014001; IPR027417; IPR001650; IPR013320; IPR003877; ","\"DEAD/DEAH box helicase domain; RNA helicase, DEAD-box type, Q motif; B30.2/SPRY domain; Helicase superfamily 1/2, ATP-binding domain; P-loop containing nucleoside triphosphate hydrolase; Helicase, C-terminal; Concanavalin A-like lectin/glucanase domain; SPRY domain; \"\r"]
["Q92522","Histone H1x OS=Homo sapiens OX=9606 GN=H1FX","H1FX",22.487,29.985,21.1,4,4,4,0.83,0.963,0.831,1.169,1.041,1.162,1.285,0.0154,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0016043 cellular component organization; GO:0034728 nucleosome organization; GO:0034622 cellular macromolecular complex assembly; GO:0006333 chromatin assembly or disassembly; GO:0043933 macromolecular complex subunit organization; GO:0065004 protein-DNA complex assembly; GO:0006323 DNA packaging; GO:0006334 nucleosome assembly; GO:0051276 chromosome organization; GO:0022607 cellular component assembly; GO:0006996 organelle organization; GO:0065003 macromolecular complex assembly; GO:0006325 chromatin organization; GO:0031497 chromatin assembly; GO:0009987 cellular process; GO:0071824 protein-DNA complex subunit organization; GO:0071840 cellular component organization or biogenesis; GO:0071103 DNA conformation change; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005730 nucleolus; GO:0005623 cell; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0000786 nucleosome; GO:0043228 non-membrane-bounded organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031974 membrane-enclosed lumen; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0000785 chromatin; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0043227 membrane-bounded organelle; GO:0044815 DNA packaging complex; GO:0032993 protein-DNA complex; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0050839 cell adhesion molecule binding; GO:0003677 DNA binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; ","K11275",null,null,"IPR011991; IPR005818; ","\"Winged helix-turn-helix DNA-binding domain; Linker histone H1/H5, domain H15; \"\r"]
["Q92538","Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 OS=Homo sapiens OX=9606 GN=GBF1","GBF1",206.44,81.337,6.6,10,13,10,1.025,1.006,1,1.046,1.012,0.977,1.001,0.965,"cytoplasm\r","GO:0006901 vesicle coating; GO:0010256 endomembrane system organization; GO:0051674 localization of cell; GO:0061162 establishment of monopolar cell polarity; GO:0023051 regulation of signaling; GO:2000008 regulation of protein localization to cell surface; GO:1903008 organelle disassembly; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:1990266 neutrophil migration; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0010646 regulation of cell communication; GO:0051649 establishment of localization in cell; GO:0071621 granulocyte chemotaxis; GO:0097529 myeloid leukocyte migration; GO:0070972 protein localization to endoplasmic reticulum; GO:0048308 organelle inheritance; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0048199 vesicle targeting, to, from or within Golgi; GO:0048194 Golgi vesicle budding; GO:0033365 protein localization to organelle; GO:0044419 interspecies interaction between organisms; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0051726 regulation of cell cycle; GO:0051056 regulation of small GTPase mediated signal transduction; GO:0070887 cellular response to chemical stimulus; GO:0051716 cellular response to stimulus; GO:0051650 establishment of vesicle localization; GO:0006895 Golgi to endosome transport; GO:0044763 single-organism cellular process; GO:0097111 endoplasmic reticulum-Golgi intermediate compartment organization; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0048870 cell motility; GO:0007163 establishment or maintenance of cell polarity; GO:0006935 chemotaxis; GO:0051704 multi-organism process; GO:0090166 Golgi disassembly; GO:0016197 endosomal transport; GO:0006810 transport; GO:1902589 single-organism organelle organization; GO:0030593 neutrophil chemotaxis; GO:0050900 leukocyte migration; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0042147 retrograde transport, endosome to Golgi; GO:0051336 regulation of hydrolase activity; GO:0007030 Golgi organization; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0043087 regulation of GTPase activity; GO:0065009 regulation of molecular function; GO:0042330 taxis; GO:0040011 locomotion; GO:0061339 establishment or maintenance of monopolar cell polarity; GO:0050794 regulation of cellular process; GO:0051640 organelle localization; GO:0016477 cell migration; GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0007346 regulation of mitotic cell cycle; GO:0002252 immune effector process; GO:0048313 Golgi inheritance; GO:0048193 Golgi vesicle transport; GO:0046578 regulation of Ras protein signal transduction; GO:0060326 cell chemotaxis; GO:0006903 vesicle targeting; GO:0050896 response to stimulus; GO:0048205 COPI coating of Golgi vesicle; GO:0060341 regulation of cellular localization; GO:0097530 granulocyte migration; GO:0048200 Golgi transport vesicle coating; GO:0051345 positive regulation of hydrolase activity; GO:0072593 reactive oxygen species metabolic process; GO:0016032 viral process; GO:0051648 vesicle localization; GO:0030010 establishment of cell polarity; GO:1903420 protein localization to endoplasmic reticulum tubular network; GO:0032880 regulation of protein localization; GO:0016482 cytosolic transport; GO:0034613 cellular protein localization; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:1903409 reactive oxygen species biosynthetic process; GO:0034067 protein localization to Golgi apparatus; GO:1902531 regulation of intracellular signal transduction; GO:0043547 positive regulation of GTPase activity; GO:0016192 vesicle-mediated transport; GO:0016050 vesicle organization; GO:0002376 immune system process; GO:0071702 organic substance transport; GO:0051656 establishment of organelle localization; GO:0002263 cell activation involved in immune response; GO:0043085 positive regulation of catalytic activity; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0030595 leukocyte chemotaxis; GO:0006890 retrograde vesicle-mediated transport, Golgi to ER; GO:0006996 organelle organization; GO:0006900 membrane budding; GO:0061024 membrane organization; GO:0035964 COPI-coated vesicle budding; GO:0006928 movement of cell or subcellular component; GO:0022411 cellular component disassembly; GO:0001775 cell activation; GO:0032012 regulation of ARF protein signal transduction; GO:0006955 immune response; GO:0006892 post-Golgi vesicle-mediated transport; GO:0051179 localization; GO:0006888 ER to Golgi vesicle-mediated transport; GO:1903827 regulation of cellular protein localization; GO:0070973 protein localization to endoplasmic reticulum exit site; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0005801 cis-Golgi network; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0042579 microbody; GO:0098791 Golgi subcompartment; GO:0044431 Golgi apparatus part; GO:0043227 membrane-bounded organelle; GO:0005811 lipid particle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005788 endoplasmic reticulum lumen; GO:0031252 cell leading edge; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005777 peroxisome; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0005795 Golgi stack; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044432 endoplasmic reticulum part; GO:0005793 endoplasmic reticulum-Golgi intermediate compartment; GO:0005802 trans-Golgi network; GO:0005794 Golgi apparatus; GO:0031984 organelle subcompartment; GO:0044444 cytoplasmic part; ","GO:1901981 phosphatidylinositol phosphate binding; GO:0005086 ARF guanyl-nucleotide exchange factor activity; GO:0005085 guanyl-nucleotide exchange factor activity; GO:0005488 binding; GO:0005543 phospholipid binding; GO:0035091 phosphatidylinositol binding; GO:0043167 ion binding; GO:0008289 lipid binding; GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding; GO:0080025 phosphatidylinositol-3,5-bisphosphate binding; GO:0005515 protein binding; GO:0043168 anion binding; GO:0098772 molecular function regulator; GO:1902936 phosphatidylinositol bisphosphate binding; ","K18443","GBF1; golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1","hsa04144 Endocytosis - Homo sapiens (human); ","IPR023394; IPR032691; IPR000904; IPR016024; ","\"Sec7 domain, alpha orthogonal bundle; Guanine nucleotide exchange factor, N-terminal; Sec7 domain; Armadillo-type fold; \"\r"]
["Q92552","28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27","MRPS27",47.611,3.3981,2.7,1,1,1,0.771,0.807,0.936,1.033,1.381,1.051,1.378,0.0466,"mitochondria\r","GO:0016043 cellular component organization; GO:0006518 peptide metabolic process; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0043241 protein complex disassembly; GO:0008152 metabolic process; GO:0043624 cellular protein complex disassembly; GO:0034641 cellular nitrogen compound metabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0006412 translation; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0071822 protein complex subunit organization; GO:0006414 translational elongation; GO:0043043 peptide biosynthetic process; GO:0044763 single-organism cellular process; GO:0032984 macromolecular complex disassembly; GO:0006807 nitrogen compound metabolic process; GO:0032543 mitochondrial translation; GO:0043603 cellular amide metabolic process; GO:0044238 primary metabolic process; GO:0070126 mitochondrial translational termination; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0006415 translational termination; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0070125 mitochondrial translational elongation; GO:0044260 cellular macromolecule metabolic process; GO:0022411 cellular component disassembly; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:1901564 organonitrogen compound metabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0005840 ribosome; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0031090 organelle membrane; GO:0043232 intracellular non-membrane-bounded organelle; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0043228 non-membrane-bounded organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005740 mitochondrial envelope; GO:0043226 organelle; GO:0005622 intracellular; GO:0044464 cell part; GO:0031975 envelope; GO:0019866 organelle inner membrane; GO:1990904 ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0030529 intracellular ribonucleoprotein complex; GO:0005743 mitochondrial inner membrane; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ","K17406"]
["Q92597","Protein NDRG1 OS=Homo sapiens OX=9606 GN=NDRG1","NDRG1",42.835,88.11,33.8,8,18,8,1.049,1.002,1.013,1.019,0.989,0.938,0.961,0.228,"cyto_nucl\r","GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0010256 endomembrane system organization; GO:0045321 leukocyte activation; GO:0007272 ensheathment of neurons; GO:0048869 cellular developmental process; GO:0014037 Schwann cell differentiation; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0045576 mast cell activation; GO:0014044 Schwann cell development; GO:0008285 negative regulation of cell proliferation; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0010035 response to inorganic substance; GO:0051726 regulation of cell cycle; GO:0007422 peripheral nervous system development; GO:0043217 myelin maintenance; GO:0070887 cellular response to chemical stimulus; GO:0002274 myeloid leukocyte activation; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0032287 peripheral nervous system myelin maintenance; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0007009 plasma membrane organization; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0010038 response to metal ion; GO:0042552 myelination; GO:0042063 gliogenesis; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032292 peripheral nervous system axon ensheathment; GO:0021782 glial cell development; GO:1901978 positive regulation of cell cycle checkpoint; GO:0048856 anatomical structure development; GO:0090231 regulation of spindle checkpoint; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0042127 regulation of cell proliferation; GO:0009628 response to abiotic stimulus; GO:0008366 axon ensheathment; GO:0043067 regulation of programmed cell death; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:0022011 myelination in peripheral nervous system; GO:0048468 cell development; GO:0030330 DNA damage response, signal transduction by p53 class mediator; GO:0030154 cell differentiation; GO:0001666 response to hypoxia; GO:0070482 response to oxygen levels; GO:0090232 positive regulation of spindle checkpoint; GO:0042770 signal transduction in response to DNA damage; GO:0007275 multicellular organism development; GO:0071453 cellular response to oxygen levels; GO:0009987 cellular process; GO:0071456 cellular response to hypoxia; GO:1901976 regulation of cell cycle checkpoint; GO:0006950 response to stress; GO:0035556 intracellular signal transduction; GO:0048731 system development; GO:0072331 signal transduction by p53 class mediator; GO:0044802 single-organism membrane organization; GO:0002376 immune system process; GO:0048518 positive regulation of biological process; GO:0006974 cellular response to DNA damage stimulus; GO:0010001 glial cell differentiation; GO:0044767 single-organism developmental process; GO:0061024 membrane organization; GO:0001775 cell activation; GO:0036293 response to decreased oxygen levels; GO:0042981 regulation of apoptotic process; GO:0036294 cellular response to decreased oxygen levels; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005874 microtubule; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0055038 recycling endosome membrane; GO:0044424 intracellular part; GO:0099512 supramolecular fiber; GO:0005913 cell-cell adherens junction; GO:0005911 cell-cell junction; GO:0005623 cell; GO:0099080 supramolecular complex; GO:0044422 organelle part; GO:0055037 recycling endosome; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005856 cytoskeleton; GO:0005815 microtubule organizing center; GO:0015630 microtubule cytoskeleton; GO:0043209 myelin sheath; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0005912 adherens junction; GO:0048471 perinuclear region of cytoplasm; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0010008 endosome membrane; GO:0099513 polymeric cytoskeletal fiber; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0099081 supramolecular polymer; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0005813 centrosome; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0031267 small GTPase binding; GO:0050839 cell adhesion molecule binding; GO:0008092 cytoskeletal protein binding; GO:0017016 Ras GTPase binding; GO:0008017 microtubule binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0015631 tubulin binding; GO:0043015 gamma-tubulin binding; GO:0005515 protein binding; GO:0051020 GTPase binding; GO:0017137 Rab GTPase binding; GO:0019899 enzyme binding; ","K18266",null,null,"IPR029058; ","Alpha/Beta hydrolase fold; \r"]
["Q92599","Septin-8 OS=Homo sapiens OX=9606 GN=SEPT8","SEPT8",55.756,25.579,19.9,9,15,6,1.013,1.019,0.999,0.982,0.969,1.02,0.98,0.287,"nucleus\r",null,"GO:0005856 cytoskeleton; GO:0043226 organelle; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0043209 myelin sheath; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0043228 non-membrane-bounded organelle; ","GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0036094 small molecule binding; ","K16939","SEPT6_8_11; septin 6/8/11","hsa05100 Bacterial invasion of epithelial cells - Homo sapiens (human); ","IPR027417; IPR030379; ","P-loop containing nucleoside triphosphate hydrolase; Septin-type guanine nucleotide-binding (G) domain; \r"]
["Q92600","CCR4-NOT transcription complex subunit 9 OS=Homo sapiens OX=9606 GN=CNOT9","CNOT9",33.631,18.841,12,3,3,3,0.924,1.013,1.067,1.067,1.047,0.892,1.001,0.992,"cyto_nucl\r","GO:0044700 single organism signaling; GO:1902807 negative regulation of cell cycle G1/S phase transition; GO:0007166 cell surface receptor signaling pathway; GO:0022414 reproductive process; GO:0097659 nucleic acid-templated transcription; GO:0010608 posttranscriptional regulation of gene expression; GO:0071345 cellular response to cytokine stimulus; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0072431 signal transduction involved in mitotic G1 DNA damage checkpoint; GO:1902403 signal transduction involved in mitotic DNA integrity checkpoint; GO:0008152 metabolic process; GO:0044093 positive regulation of molecular function; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0043170 macromolecule metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0090068 positive regulation of cell cycle process; GO:0051716 cellular response to stimulus; GO:0000278 mitotic cell cycle; GO:0003006 developmental process involved in reproduction; GO:0018130 heterocycle biosynthetic process; GO:0044773 mitotic DNA damage checkpoint; GO:0080090 regulation of primary metabolic process; GO:2000134 negative regulation of G1/S transition of mitotic cell cycle; GO:0044763 single-organism cellular process; GO:0034249 negative regulation of cellular amide metabolic process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0010948 negative regulation of cell cycle process; GO:0072413 signal transduction involved in mitotic cell cycle checkpoint; GO:0031047 gene silencing by RNA; GO:1902400 intracellular signal transduction involved in G1 DNA damage checkpoint; GO:0032269 negative regulation of cellular protein metabolic process; GO:0048583 regulation of response to stimulus; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0000003 reproduction; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0007346 regulation of mitotic cell cycle; GO:0017148 negative regulation of translation; GO:0033144 negative regulation of intracellular steroid hormone receptor signaling pathway; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0030330 DNA damage response, signal transduction by p53 class mediator; GO:0044270 cellular nitrogen compound catabolic process; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1902402 signal transduction involved in mitotic DNA damage checkpoint; GO:1901987 regulation of cell cycle phase transition; GO:0009889 regulation of biosynthetic process; GO:0044819 mitotic G1/S transition checkpoint; GO:0007093 mitotic cell cycle checkpoint; GO:0007548 sex differentiation; GO:0051171 regulation of nitrogen compound metabolic process; GO:0044248 cellular catabolic process; GO:2000325 regulation of ligand-dependent nuclear receptor transcription coactivator activity; GO:0034655 nucleobase-containing compound catabolic process; GO:0009966 regulation of signal transduction; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0045787 positive regulation of cell cycle; GO:2000327 positive regulation of ligand-dependent nuclear receptor transcription coactivator activity; GO:0006950 response to stress; GO:0072331 signal transduction by p53 class mediator; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0006974 cellular response to DNA damage stimulus; GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway; GO:0034248 regulation of cellular amide metabolic process; GO:0009890 negative regulation of biosynthetic process; GO:2000045 regulation of G1/S transition of mitotic cell cycle; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0044783 G1 DNA damage checkpoint; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:2001141 regulation of RNA biosynthetic process; GO:0045930 negative regulation of mitotic cell cycle; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0000077 DNA damage checkpoint; GO:0044774 mitotic DNA integrity checkpoint; GO:0007154 cell communication; GO:1901991 negative regulation of mitotic cell cycle phase transition; GO:1902806 regulation of cell cycle G1/S phase transition; GO:0000075 cell cycle checkpoint; GO:1901361 organic cyclic compound catabolic process; GO:0051726 regulation of cell cycle; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0031571 mitotic G1 DNA damage checkpoint; GO:0010468 regulation of gene expression; GO:0034097 response to cytokine; GO:0031326 regulation of cellular biosynthetic process; GO:0031570 DNA integrity checkpoint; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0006401 RNA catabolic process; GO:0016070 RNA metabolic process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0033143 regulation of intracellular steroid hormone receptor signaling pathway; GO:0072401 signal transduction involved in DNA integrity checkpoint; GO:0045786 negative regulation of cell cycle; GO:0072395 signal transduction involved in cell cycle checkpoint; GO:0006725 cellular aromatic compound metabolic process; GO:1901988 negative regulation of cell cycle phase transition; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0042770 signal transduction in response to DNA damage; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0019221 cytokine-mediated signaling pathway; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0071156 regulation of cell cycle arrest; GO:0044265 cellular macromolecule catabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0072422 signal transduction involved in DNA damage checkpoint; GO:0035556 intracellular signal transduction; GO:0010629 negative regulation of gene expression; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening; GO:0048585 negative regulation of response to stimulus; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0016458 gene silencing; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0033146 regulation of intracellular estrogen receptor signaling pathway; GO:0006417 regulation of translation; GO:0051246 regulation of protein metabolic process; GO:0009057 macromolecule catabolic process; GO:0071158 positive regulation of cell cycle arrest; GO:0051248 negative regulation of protein metabolic process; GO:0010467 gene expression; GO:0022402 cell cycle process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0065007 biological regulation; GO:0046700 heterocycle catabolic process; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0043232 intracellular non-membrane-bounded organelle; GO:0000932 P-body; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0043228 non-membrane-bounded organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:0035770 ribonucleoprotein granule; GO:0030015 CCR4-NOT core complex; GO:0030014 CCR4-NOT complex; GO:1990904 ribonucleoprotein complex; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0030529 intracellular ribonucleoprotein complex; GO:0044444 cytoplasmic part; ","GO:0019904 protein domain specific binding; GO:0005515 protein binding; GO:0042802 identical protein binding; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0046983 protein dimerization activity; ","K12606","RCD1; CCR4-NOT transcription complex subunit 9","hsa03018 RNA degradation - Homo sapiens (human); ","IPR011989; IPR016024; ","Armadillo-like helical; Armadillo-type fold; \r"]
["Q92620","Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 OS=Homo sapiens OX=9606 GN=DHX38","DHX38",140.5,5.5308,2.8,3,3,3,0.915,0.931,0.812,1.101,1.161,1.077,1.256,0.00906,"nucleus\r","GO:0050658 RNA transport; GO:0097659 nucleic acid-templated transcription; GO:0009058 biosynthetic process; GO:0051168 nuclear export; GO:0051169 nuclear transport; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006353 DNA-templated transcription, termination; GO:0071427 mRNA-containing ribonucleoprotein complex export from nucleus; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0050657 nucleic acid transport; GO:0015931 nucleobase-containing compound transport; GO:0043170 macromolecule metabolic process; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0006396 RNA processing; GO:0018130 heterocycle biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0006611 protein export from nucleus; GO:0071166 ribonucleoprotein complex localization; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:0006810 transport; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0044260 cellular macromolecule metabolic process; GO:0006913 nucleocytoplasmic transport; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0031123 RNA 3'-end processing; GO:0046907 intracellular transport; GO:0006725 cellular aromatic compound metabolic process; GO:0031124 mRNA 3'-end processing; GO:0051028 mRNA transport; GO:0051236 establishment of RNA localization; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0006886 intracellular protein transport; GO:0034641 cellular nitrogen compound metabolic process; GO:0034613 cellular protein localization; GO:0009059 macromolecule biosynthetic process; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0006406 mRNA export from nucleus; GO:0006369 termination of RNA polymerase II transcription; GO:0006403 RNA localization; GO:0006405 RNA export from nucleus; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0034645 cellular macromolecule biosynthetic process; GO:0071426 ribonucleoprotein complex export from nucleus; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006366 transcription from RNA polymerase II promoter; GO:0010467 gene expression; GO:0051179 localization; GO:0071705 nitrogen compound transport; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005681 spliceosomal complex; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0071013 catalytic step 2 spliceosome; GO:1990904 ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0030529 intracellular ribonucleoprotein complex; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0008026 ATP-dependent helicase activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0016887 ATPase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0004004 ATP-dependent RNA helicase activity; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003723 RNA binding; GO:0005524 ATP binding; GO:0070035 purine NTP-dependent helicase activity; GO:0004386 helicase activity; GO:0008186 RNA-dependent ATPase activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003724 RNA helicase activity; GO:0003676 nucleic acid binding; GO:0042623 ATPase activity, coupled; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; ","K12815","DHX38; pre-mRNA-splicing factor ATP-dependent RNA helicase DHX38/PRP16 [EC:3.6.4.13]","hsa03040 Spliceosome - Homo sapiens (human); ","IPR007502; IPR011545; IPR011709; IPR014001; IPR027417; IPR001650; ","\"Helicase-associated domain; DEAD/DEAH box helicase domain; Domain of unknown function DUF1605; Helicase superfamily 1/2, ATP-binding domain; P-loop containing nucleoside triphosphate hydrolase; Helicase, C-terminal; \"\r"]
["Q92621","Nuclear pore complex protein Nup205 OS=Homo sapiens OX=9606 GN=NUP205","NUP205",227.92,40.225,4.6,8,8,8,0.999,0.951,0.944,1.057,0.98,0.974,1.04,0.284,"plasma membrane\r","GO:0044085 cellular component biogenesis; GO:0050658 RNA transport; GO:0051169 nuclear transport; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:1902583 multi-organism intracellular transport; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0032879 regulation of localization; GO:0065003 macromolecular complex assembly; GO:0015931 nucleobase-containing compound transport; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0075733 intracellular transport of virus; GO:0044419 interspecies interaction between organisms; GO:0008104 protein localization; GO:0044765 single-organism transport; GO:0051031 tRNA transport; GO:0007077 mitotic nuclear envelope disassembly; GO:0000278 mitotic cell cycle; GO:0018130 heterocycle biosynthetic process; GO:0044763 single-organism cellular process; GO:0032774 RNA biosynthetic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0006611 protein export from nucleus; GO:0051704 multi-organism process; GO:0006810 transport; GO:0080135 regulation of cellular response to stress; GO:0031047 gene silencing by RNA; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0006913 nucleocytoplasmic transport; GO:1901362 organic cyclic compound biosynthetic process; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0016925 protein sumoylation; GO:0051028 mRNA transport; GO:0044267 cellular protein metabolic process; GO:0080134 regulation of response to stress; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0051236 establishment of RNA localization; GO:0051292 nuclear pore complex assembly; GO:0046483 heterocycle metabolic process; GO:1902578 single-organism localization; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0051081 nuclear envelope disassembly; GO:1902580 single-organism cellular localization; GO:0034613 cellular protein localization; GO:0006461 protein complex assembly; GO:0046794 transport of virus; GO:0006403 RNA localization; GO:0006405 RNA export from nucleus; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0044766 multi-organism transport; GO:0045184 establishment of protein localization; GO:0006409 tRNA export from nucleus; GO:0032446 protein modification by small protein conjugation; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0043412 macromolecule modification; GO:0051179 localization; GO:0010256 endomembrane system organization; GO:0044699 single-organism process; GO:0051168 nuclear export; GO:1902581 multi-organism cellular localization; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0051234 establishment of localization; GO:0071431 tRNA-containing ribonucleoprotein complex export from nucleus; GO:0046931 pore complex assembly; GO:0071427 mRNA-containing ribonucleoprotein complex export from nucleus; GO:0051649 establishment of localization in cell; GO:0050657 nucleic acid transport; GO:0022607 cellular component assembly; GO:0033036 macromolecule localization; GO:0010827 regulation of glucose transport; GO:0010468 regulation of gene expression; GO:0071822 protein complex subunit organization; GO:0006999 nuclear pore organization; GO:1901360 organic cyclic compound metabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0010605 negative regulation of macromolecule metabolic process; GO:0071166 ribonucleoprotein complex localization; GO:1902582 single-organism intracellular transport; GO:0016070 RNA metabolic process; GO:0030397 membrane disassembly; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0019222 regulation of metabolic process; GO:1900034 regulation of cellular response to heat; GO:0019083 viral transcription; GO:0036211 protein modification process; GO:0070271 protein complex biogenesis; GO:0016043 cellular component organization; GO:0006997 nucleus organization; GO:1902579 multi-organism localization; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0071704 organic substance metabolic process; GO:0006998 nuclear envelope organization; GO:0018205 peptidyl-lysine modification; GO:0016032 viral process; GO:0006886 intracellular protein transport; GO:0019080 viral gene expression; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0043623 cellular protein complex assembly; GO:0006406 mRNA export from nucleus; GO:0034622 cellular macromolecular complex assembly; GO:0010629 negative regulation of gene expression; GO:0051049 regulation of transport; GO:0044802 single-organism membrane organization; GO:0006807 nitrogen compound metabolic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0043933 macromolecular complex subunit organization; GO:0018193 peptidyl-amino acid modification; GO:0070727 cellular macromolecule localization; GO:0016458 gene silencing; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0071426 ribonucleoprotein complex export from nucleus; GO:0022411 cellular component disassembly; GO:0010467 gene expression; GO:0022402 cell cycle process; GO:0071705 nitrogen compound transport; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005643 nuclear pore; GO:0031090 organelle membrane; GO:0044611 nuclear pore inner ring; GO:0005635 nuclear envelope; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031965 nuclear membrane; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0031975 envelope; GO:0034399 nuclear periphery; GO:0043227 membrane-bounded organelle; GO:0043234 protein complex; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0017056 structural constituent of nuclear pore; GO:0005198 structural molecule activity; GO:0005488 binding; ","K14310","NUP205; nuclear pore complex protein Nup205","hsa03013 RNA transport - Homo sapiens (human); "]
["Q92688","Acidic leucine-rich nuclear phosphoprotein 32 family member B OS=Homo sapiens OX=9606 GN=ANP32B","ANP32B",28.787,77.313,31.9,7,15,5,0.959,0.885,0.899,1.132,1.074,1.048,1.186,6.96E-3,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0051093 negative regulation of developmental process; GO:0010941 regulation of cell death; GO:0032270 positive regulation of cellular protein metabolic process; GO:0007420 brain development; GO:0044699 single-organism process; GO:0006334 nucleosome assembly; GO:0009893 positive regulation of metabolic process; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0046824 positive regulation of nucleocytoplasmic transport; GO:0060322 head development; GO:0045596 negative regulation of cell differentiation; GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0031497 chromatin assembly; GO:0071824 protein-DNA complex subunit organization; GO:0071103 DNA conformation change; GO:0052548 regulation of endopeptidase activity; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0006333 chromatin assembly or disassembly; GO:0010950 positive regulation of endopeptidase activity; GO:0080090 regulation of primary metabolic process; GO:2000116 regulation of cysteine-type endopeptidase activity; GO:0048522 positive regulation of cellular process; GO:0001944 vasculature development; GO:0032386 regulation of intracellular transport; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0010942 positive regulation of cell death; GO:0051050 positive regulation of transport; GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0065004 protein-DNA complex assembly; GO:0048513 animal organ development; GO:0032268 regulation of cellular protein metabolic process; GO:0043583 ear development; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:0046825 regulation of protein export from nucleus; GO:0050790 regulation of catalytic activity; GO:0007417 central nervous system development; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051223 regulation of protein transport; GO:0006325 chromatin organization; GO:0052547 regulation of peptidase activity; GO:0048856 anatomical structure development; GO:0010952 positive regulation of peptidase activity; GO:0043068 positive regulation of programmed cell death; GO:0051222 positive regulation of protein transport; GO:0072359 circulatory system development; GO:0050794 regulation of cellular process; GO:0034728 nucleosome organization; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:2001056 positive regulation of cysteine-type endopeptidase activity; GO:0090316 positive regulation of intracellular protein transport; GO:0060255 regulation of macromolecule metabolic process; GO:1903829 positive regulation of cellular protein localization; GO:0043067 regulation of programmed cell death; GO:0043065 positive regulation of apoptotic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0070201 regulation of establishment of protein localization; GO:0060341 regulation of cellular localization; GO:0006323 DNA packaging; GO:0045862 positive regulation of proteolysis; GO:0051345 positive regulation of hydrolase activity; GO:0021591 ventricular system development; GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0032880 regulation of protein localization; GO:0007275 multicellular organism development; GO:0033157 regulation of intracellular protein transport; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0034622 cellular macromolecular complex assembly; GO:0051049 regulation of transport; GO:0032388 positive regulation of intracellular transport; GO:0048731 system development; GO:0072358 cardiovascular system development; GO:0030162 regulation of proteolysis; GO:0048839 inner ear development; GO:0060021 palate development; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0043933 macromolecular complex subunit organization; GO:0046827 positive regulation of protein export from nucleus; GO:0051247 positive regulation of protein metabolic process; GO:1904951 positive regulation of establishment of protein localization; GO:0046822 regulation of nucleocytoplasmic transport; GO:0051276 chromosome organization; GO:0051246 regulation of protein metabolic process; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0031325 positive regulation of cellular metabolic process; GO:0007423 sensory organ development; GO:0050793 regulation of developmental process; GO:0042981 regulation of apoptotic process; GO:1903827 regulation of cellular protein localization; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0042393 histone binding; GO:0005515 protein binding; GO:0070063 RNA polymerase binding; GO:0019899 enzyme binding; GO:0005488 binding; ","K18647",null,null,"IPR003603; IPR032675; ","\"U2A'/phosphoprotein 32 family A, C-terminal; Leucine-rich repeat domain, L domain-like; \"\r"]
["Q92734","Protein TFG OS=Homo sapiens OX=9606 GN=TFG","TFG",43.447,51.518,16,5,7,5,0.994,1.049,1.068,0.976,0.854,1.009,0.913,0.166,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0051640 organelle localization; GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0016043 cellular component organization; GO:0006901 vesicle coating; GO:0046907 intracellular transport; GO:0048207 vesicle targeting, rough ER to cis-Golgi; GO:0048208 COPII vesicle coating; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0048193 Golgi vesicle transport; GO:0044699 single-organism process; GO:0006903 vesicle targeting; GO:0050896 response to stimulus; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0023056 positive regulation of signaling; GO:0065003 macromolecular complex assembly; GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling; GO:0048199 vesicle targeting, to, from or within Golgi; GO:0051648 vesicle localization; GO:0010647 positive regulation of cell communication; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0051716 cellular response to stimulus; GO:0051650 establishment of vesicle localization; GO:1902531 regulation of intracellular signal transduction; GO:0071822 protein complex subunit organization; GO:0090114 COPII-coated vesicle budding; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0016050 vesicle organization; GO:0051656 establishment of organelle localization; GO:0023052 signaling; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0043933 macromolecular complex subunit organization; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0006996 organelle organization; GO:0048583 regulation of response to stimulus; GO:0006900 membrane budding; GO:0061024 membrane organization; GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling; GO:0009967 positive regulation of signal transduction; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0070271 protein complex biogenesis; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0098588 bounding membrane of organelle; GO:0031090 organelle membrane; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0005794 Golgi apparatus; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0042802 identical protein binding; GO:0004871 signal transducer activity; GO:0005488 binding; ","K09292","TFG; protein TFG","hsa05216 Thyroid cancer - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); ","IPR000270; ","PB1 domain; \r"]
["Q92769","Histone deacetylase 2 OS=Homo sapiens OX=9606 GN=HDAC2","HDAC2",55.364,16.631,8.8,3,3,2,0.962,1.041,0.973,1.015,0.996,1.02,1.018,0.503,"cytoplasm\r",{"$cut":{"chars":18019,"head":"GO:0035094 response to nicotine; GO:0010941 regulation of cell death; GO:2000171 negative regulation of dendrite development; GO:0014013 regulation of gliogenesis; GO:0032680 regulation of tumor necrosis factor production; GO:0009891 positive regulation of biosynthetic process; GO:0044237 cellular metabolic process; GO:0009607 response to biotic stimulus; GO:0009913 epidermal cell differentiation; GO:0008152 metabolic process; GO:0032732 positive regulation of interleukin-1 production; GO:0042516 regulation of tyrosine phosphorylation of Stat3 protein; GO:0008544 epidermis development; GO:0009790 embryo development; GO:0048598 embryonic morphogenesis; GO:0090596 sensory organ morphogenesis; GO:0061197 fungiform papilla morphogenesis; GO:0048713 regulation of oligodendrocyte differentiation; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0043588 skin development; GO:0060359 response to ammonium ion; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0071559 response to transforming growth factor beta; GO:0051704 multi-organism process; GO:0071396 cellular response to lipid; GO:0010243 response to organonitrogen compound; GO:1903350 response to dopamine; GO:0048583 regulation of response to stimulus; GO:0045665 negative regulation of neuron differentiation; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:1901698 response to nitrogen compound; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0010721 negative regulation of cell development; GO:0060548 negative regulation of cell death; GO:0010975 regulation of neuron projection development; GO:0014897 striated muscle hypertrophy; GO:0030855 epithelial cell differentiation; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0044707 single-multicellular organism process; GO:0001819 positive regulation of cytokine production; GO:0042303 molting cycle; GO:0016570 histone modification; GO:1901700 response to oxygen-containing compound; GO:0048519 negative regulation of biological process; GO:0045892 negative regulation of transcription, DNA-templated; GO:0042493 response to drug; GO:0009653 anatomical structure morphogenesis; GO:0001654 eye development; GO:0061196 fungiform papilla development; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0071229 cellular response to acid chemical; GO:0009889 regulation of biosynthetic process; GO:0031345 negative regulation of cell projection organization; GO:0070482 response to oxygen levels; GO:1902680 positive regulation of RNA biosynthetic process; GO:0030534 adult behavior; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0006950 response to stress; GO:0032496 response to lipopolysaccharide; GO:0042733 embryonic digit morphogenesis; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0010977 negative regulation of neuron projection development; GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein; GO:0010033 response to organic substance; GO:0032922 circadian regulation of gene expression; GO:1901576 organic substance biosynthetic process; GO:0042633 hair cycle; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0009890 negative regulation of biosynthetic process; GO:0010718 positive regulation of epithelial to mesenchymal transition; GO:0030326 embryonic limb morphogenesis; GO:0042542 response to hydrogen peroxide; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0071870 cellular response to catecholamine stimulus; GO:0043412 macromolecule modification; GO:0007423 sensory organ development; GO:0008284 positive regulation of cell proliferation; GO:0051093 negative regulation of developmental process; GO:0003012 muscle system process; GO:0044246 regulation of multicellular o"}},"GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0017053 transcriptional repressor complex; GO:0044424 intracellular part; GO:0070603 SWI/SNF superfamily-type complex; GO:0005623 cell; GO:0000118 histone deacetylase complex; GO:0044422 organelle part; GO:0090568 nuclear transcriptional repressor complex; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0016580 Sin3 complex; GO:0044454 nuclear chromosome part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0090545 CHD-type complex; GO:0000790 nuclear chromatin; GO:0016581 NuRD complex; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0035097 histone methyltransferase complex; GO:1990234 transferase complex; GO:0034708 methyltransferase complex; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0070822 Sin3-type complex; GO:0000785 chromatin; GO:0035098 ESC/E(Z) complex; GO:0000228 nuclear chromosome; GO:0031519 PcG protein complex; GO:0043234 protein complex; GO:0044428 nuclear part; ","GO:0032041 NAD-dependent histone deacetylase activity (H3-K14 specific); GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0003682 chromatin binding; GO:0001047 core promoter binding; GO:0000975 regulatory region DNA binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0070491 repressing transcription factor binding; GO:0003824 catalytic activity; GO:0001085 RNA polymerase II transcription factor binding; GO:0005488 binding; GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; GO:0003677 DNA binding; GO:0003723 RNA binding; GO:0031072 heat shock protein binding; GO:0001103 RNA polymerase II repressing transcription factor binding; GO:0017136 NAD-dependent histone deacetylase activity; GO:0043565 sequence-specific DNA binding; GO:0004407 histone deacetylase activity; GO:0001067 regulatory region nucleic acid binding; GO:0031078 histone deacetylase activity (H3-K14 specific); GO:0033558 protein deacetylase activity; GO:0044212 transcription regulatory region DNA binding; GO:0003676 nucleic acid binding; GO:0019213 deacetylase activity; GO:0051059 NF-kappaB binding; GO:0034979 NAD-dependent protein deacetylase activity; GO:0008134 transcription factor binding; GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; GO:0019899 enzyme binding; ","K06067","HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]","hsa04330 Notch signaling pathway - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); hsa05031 Amphetamine addiction - Homo sapiens (human); hsa05220 Chronic myeloid leukemia - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa05203 Viral carcinogenesis - Homo sapiens (human); hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04110 Cell cycle - Homo sapiens (human); hsa05206 MicroRNAs in cancer - Homo sapiens (human); hsa05034 Alcoholism - Homo sapiens (human); hsa04213 Longevity regulating pathway - multiple species - Homo sapiens (human); hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human); ","IPR023801; ","Histone deacetylase domain; \r"]
["Q92797","Symplekin OS=Homo sapiens OX=9606 GN=SYMPK","SYMPK",141.15,16.903,1.3,1,2,1,0.968,0.957,0.961,1.093,0.977,1.05,1.081,0.145,"nucleus\r","GO:0050658 RNA transport; GO:0032270 positive regulation of cellular protein metabolic process; GO:0097659 nucleic acid-templated transcription; GO:0009058 biosynthetic process; GO:0051168 nuclear export; GO:0051169 nuclear transport; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006353 DNA-templated transcription, termination; GO:0022610 biological adhesion; GO:0071427 mRNA-containing ribonucleoprotein complex export from nucleus; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0009893 positive regulation of metabolic process; GO:0050657 nucleic acid transport; GO:0015931 nucleobase-containing compound transport; GO:0007155 cell adhesion; GO:0035303 regulation of dephosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0043170 macromolecule metabolic process; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0006396 RNA processing; GO:0018130 heterocycle biosynthetic process; GO:0051174 regulation of phosphorus metabolic process; GO:0045937 positive regulation of phosphate metabolic process; GO:0043631 RNA polyadenylation; GO:0080090 regulation of primary metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0006611 protein export from nucleus; GO:0071166 ribonucleoprotein complex localization; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:0006810 transport; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0035306 positive regulation of dephosphorylation; GO:0006351 transcription, DNA-templated; GO:0035304 regulation of protein dephosphorylation; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006913 nucleocytoplasmic transport; GO:0019220 regulation of phosphate metabolic process; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0050794 regulation of cellular process; GO:0031123 RNA 3'-end processing; GO:0046907 intracellular transport; GO:0006725 cellular aromatic compound metabolic process; GO:0031124 mRNA 3'-end processing; GO:0006378 mRNA polyadenylation; GO:0060255 regulation of macromolecule metabolic process; GO:0051028 mRNA transport; GO:0031399 regulation of protein modification process; GO:0051236 establishment of RNA localization; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0006886 intracellular protein transport; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0034613 cellular protein localization; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0006406 mRNA export from nucleus; GO:0035307 positive regulation of protein dephosphorylation; GO:0006369 termination of RNA polymerase II transcription; GO:0006403 RNA localization; GO:0006405 RNA export from nucleus; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0031401 positive regulation of protein modification process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0051247 positive regulation of protein metabolic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0071426 ribonucleoprotein complex export from nucleus; GO:0051246 regulation of protein metabolic process; GO:0006366 transcription from RNA polymerase II promoter; GO:0031325 positive regulation of cellular metabolic process; GO:0010467 gene expression; GO:0051179 localization; GO:0071705 nitrogen compound transport; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005911 cell-cell junction; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0005654 nucleoplasm; GO:0070160 occluding junction; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0097165 nuclear stress granule; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005923 bicellular tight junction; GO:0043296 apical junction complex; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0035770 ribonucleoprotein granule; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0005488 binding; ","K06100","SYMPK; symplekin","hsa03015 mRNA surveillance pathway - Homo sapiens (human); hsa04530 Tight junction - Homo sapiens (human); ","IPR011989; IPR032460; IPR022075; IPR016024; ","\"Armadillo-like helical; Symplekin/Pta1, N-terminal; Symplekin  C-terminal; Armadillo-type fold; \"\r"]
["Q92817","Envoplakin OS=Homo sapiens OX=9606 GN=EVPL","EVPL",231.6,323.31,28.7,53,73,53,0.898,0.895,0.912,1.098,1.081,1.104,1.214,2.13e-05,"nucleus\r","GO:0044707 single-multicellular organism process; GO:0031424 keratinization; GO:0048869 cellular developmental process; GO:0018149 peptide cross-linking; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0009913 epidermal cell differentiation; GO:0008152 metabolic process; GO:0030154 cell differentiation; GO:0008544 epidermis development; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0043588 skin development; GO:0009888 tissue development; GO:0030216 keratinocyte differentiation; GO:0048731 system development; GO:0070268 cornification; GO:0044763 single-organism cellular process; GO:0044238 primary metabolic process; GO:0032501 multicellular organismal process; GO:0048513 animal organ development; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0012501 programmed cell death; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:0048856 anatomical structure development; GO:0030855 epithelial cell differentiation; ","GO:0016020 membrane; GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0070161 anchoring junction; GO:0044424 intracellular part; GO:0005911 cell-cell junction; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043228 non-membrane-bounded organelle; GO:0030057 desmosome; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0005856 cytoskeleton; GO:0045111 intermediate filament cytoskeleton; GO:0001533 cornified envelope; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0050839 cell adhesion molecule binding; GO:0030674 protein binding, bridging; GO:0019215 intermediate filament binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0044877 macromolecular complex binding; GO:0060090 binding, bridging; GO:0005515 protein binding; GO:0005198 structural molecule activity; GO:0032403 protein complex binding; ","K10383"]
["Q92820","Gamma-glutamyl hydrolase OS=Homo sapiens OX=9606 GN=GGH","GGH",35.964,38.665,30.2,8,16,8,0.904,0.931,0.896,1.049,1.105,1.103,1.193,0.00104,"extracellular\r","GO:0045321 leukocyte activation; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0009719 response to endogenous stimulus; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0010035 response to inorganic substance; GO:1901652 response to peptide; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0002443 leukocyte mediated immunity; GO:0002446 neutrophil mediated immunity; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0010038 response to metal ion; GO:0002444 myeloid leukocyte mediated immunity; GO:0006810 transport; GO:0010243 response to organonitrogen compound; GO:0032868 response to insulin; GO:0042221 response to chemical; GO:0043434 response to peptide hormone; GO:0032940 secretion by cell; GO:0044710 single-organism metabolic process; GO:1901698 response to nitrogen compound; GO:0043299 leukocyte degranulation; GO:0006082 organic acid metabolic process; GO:0043436 oxoacid metabolic process; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0045471 response to ethanol; GO:1901700 response to oxygen-containing compound; GO:0006541 glutamine metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0042493 response to drug; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0010043 response to zinc ion; GO:0006508 proteolysis; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0009064 glutamine family amino acid metabolic process; GO:0016192 vesicle-mediated transport; GO:0006807 nitrogen compound metabolic process; GO:0097305 response to alcohol; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:1901605 alpha-amino acid metabolic process; GO:0044238 primary metabolic process; GO:0043312 neutrophil degranulation; GO:0002263 cell activation involved in immune response; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0019752 carboxylic acid metabolic process; GO:0001775 cell activation; GO:0006955 immune response; GO:0051179 localization; GO:0009725 response to hormone; GO:1901564 organonitrogen compound metabolic process; GO:0006887 exocytosis; ","GO:0034774 secretory granule lumen; GO:1904724 tertiary granule lumen; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:0044422 organelle part; GO:0048770 pigment granule; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0042470 melanosome; GO:0070820 tertiary granule; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0042582 azurophil granule; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0035580 specific granule lumen; GO:0005766 primary lysosome; GO:0042581 specific granule; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0008238 exopeptidase activity; GO:0016787 hydrolase activity; GO:0008233 peptidase activity; GO:0034722 gamma-glutamyl-peptidase activity; GO:0003824 catalytic activity; GO:0008242 omega peptidase activity; ","K01307","GGH; gamma-glutamyl hydrolase [EC:3.4.19.9]","hsa01523 Antifolate resistance - Homo sapiens (human); hsa00790 Folate biosynthesis - Homo sapiens (human); ","IPR029062; ","Class I glutamine amidotransferase-like; \r"]
["Q92878","DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50","RAD50",153.89,41.194,13.6,17,21,17,0.947,1.06,1.062,1.004,0.958,0.977,0.958,0.355,"cytoplasm\r","GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0022414 reproductive process; GO:0016233 telomere capping; GO:0032204 regulation of telomere maintenance; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0044093 positive regulation of molecular function; GO:0044702 single organism reproductive process; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0051347 positive regulation of transferase activity; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0000018 regulation of DNA recombination; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0018130 heterocycle biosynthetic process; GO:0051174 regulation of phosphorus metabolic process; GO:0051054 positive regulation of DNA metabolic process; GO:0080090 regulation of primary metabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0035825 reciprocal DNA recombination; GO:0031323 regulation of cellular metabolic process; GO:0022616 DNA strand elongation; GO:0051704 multi-organism process; GO:0051053 negative regulation of DNA metabolic process; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:2001252 positive regulation of chromosome organization; GO:0044260 cellular macromolecule metabolic process; GO:0070192 chromosome organization involved in meiotic cell cycle; GO:0010604 positive regulation of macromolecule metabolic process; GO:0000019 regulation of mitotic recombination; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0032200 telomere organization; GO:0090305 nucleic acid phosphodiester bond hydrolysis; GO:0006312 mitotic recombination; GO:1901362 organic cyclic compound biosynthetic process; GO:0000003 reproduction; GO:0050794 regulation of cellular process; GO:0016310 phosphorylation; GO:0033554 cellular response to stress; GO:0006260 DNA replication; GO:0006259 DNA metabolic process; GO:0031399 regulation of protein modification process; GO:0000731 DNA synthesis involved in DNA repair; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0032844 regulation of homeostatic process; GO:0060249 anatomical structure homeostasis; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0009966 regulation of signal transduction; GO:1902531 regulation of intracellular signal transduction; GO:0006950 response to stress; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0033044 regulation of chromosome organization; GO:0006974 cellular response to DNA damage stimulus; GO:0000725 recombinational repair; GO:2001251 negative regulation of chromosome organization; GO:0051247 positive regulation of protein metabolic process; GO:0051276 chromosome organization; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0032206 positive regulation of telomere maintenance; GO:0031325 positive regulation of cellular metabolic process; GO:0019637 organophosphate metabolic process; GO:0000280 nuclear division; GO:0000723 telomere maintenance; GO:0031860 telomeric 3' overhang formation; GO:0031954 positive regulation of protein autophosphorylation; GO:0009117 nucleotide metabolic process; GO:0023051 regulation of signaling; GO:0051129 negative regulation of cellular component organization; GO:0032392 DNA geometric change; GO:0044699 single-organism process; GO:1904353 regulation of telomere capping; GO:0010833 telomere maintenance via telomere lengthening; GO:0009058 biosynthetic process; GO:0007131 reciprocal meiotic recombination; GO:0046939 nucleotide phosphorylation; GO:0044764 multi-organism cellular process; GO:0006796 phosphate-containing compound metabolic process; GO:0051130 positive regulation of cellular component organization; GO:0010646 regulation of cell communication; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0032846 positive regulation of homeostatic process; GO:0033674 positive regulation of kinase activity; GO:0006310 DNA recombination; GO:0071103 DNA conformation change; GO:0045937 positive regulation of phosphate metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0051321 meiotic cell cycle; GO:0010605 negative regulation of macromolecule metabolic process; GO:0000722 telomere maintenance via recombination; GO:0010639 negative regulation of organelle organization; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0051052 regulation of DNA metabolic process; GO:0090304 nucleic acid metabolic process; GO:0010638 positive regulation of organelle organization; GO:0000729 DNA double-strand break processing; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0006303 double-strand break repair via nonhomologous end joining; GO:0043549 regulation of kinase activity; GO:0016043 cellular component organization; GO:1903046 meiotic cell cycle process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0048285 organelle fission; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0006302 double-strand break repair; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0007127 meiosis I; GO:0000732 strand displacement; GO:0016032 viral process; GO:1901796 regulation of signal transduction by p53 class mediator; GO:0034641 cellular nitrogen compound metabolic process; GO:0071897 DNA biosynthetic process; GO:0009059 macromolecule biosynthetic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0000724 double-strand break repair via homologous recombination; GO:1904354 negative regulation of telomere capping; GO:0000726 non-recombinational repair; GO:0032508 DNA duplex unwinding; GO:0001932 regulation of protein phosphorylation; GO:0033043 regulation of organelle organization; GO:0031401 positive regulation of protein modification process; GO:0006807 nitrogen compound metabolic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0032845 negative regulation of homeostatic process; GO:0031952 regulation of protein autophosphorylation; GO:0007004 telomere maintenance via telomerase; GO:0001934 positive regulation of protein phosphorylation; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0032205 negative regulation of telomere maintenance; GO:0043085 positive regulation of catalytic activity; GO:0006281 DNA repair; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0051246 regulation of protein metabolic process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0007126 meiotic nuclear division; GO:0051128 regulation of cellular component organization; GO:0022402 cell cycle process; GO:0006278 RNA-dependent DNA biosynthetic process; GO:0007049 cell cycle; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0000784 nuclear chromosome, telomeric region; GO:0000781 chromosome, telomeric region; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0000793 condensed chromosome; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044454 nuclear chromosome part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0000790 nuclear chromatin; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0090734 site of DNA damage; GO:0098687 chromosomal region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0000785 chromatin; GO:0000228 nuclear chromosome; GO:0035861 site of double-strand break; GO:0000794 condensed nuclear chromosome; GO:0043234 protein complex; GO:0030870 Mre11 complex; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0003690 double-stranded DNA binding; GO:0004017 adenylate kinase activity; GO:0019205 nucleobase-containing compound kinase activity; GO:0003697 single-stranded DNA binding; GO:0042162 telomeric DNA binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0019201 nucleotide kinase activity; GO:0016776 phosphotransferase activity, phosphate group as acceptor; GO:0016887 ATPase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0016301 kinase activity; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003691 double-stranded telomeric DNA binding; GO:0003677 DNA binding; GO:0005524 ATP binding; GO:0030674 protein binding, bridging; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0098847 sequence-specific single stranded DNA binding; GO:0000166 nucleotide binding; GO:0043047 single-stranded telomeric DNA binding; GO:0017111 nucleoside-triphosphatase activity; GO:0043565 sequence-specific DNA binding; GO:0051880 G-quadruplex DNA binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003676 nucleic acid binding; GO:0046872 metal ion binding; GO:0060090 binding, bridging; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K10866","RAD50; DNA repair protein RAD50 [EC:3.6.-.-]","hsa03450 Non-homologous end-joining - Homo sapiens (human); hsa04218 Cellular senescence - Homo sapiens (human); hsa03440 Homologous recombination - Homo sapiens (human); ","IPR013134; IPR027417; ","\"RAD50, zinc hook; P-loop containing nucleoside triphosphate hydrolase; \"\r"]
["Q92888","Rho guanine nucleotide exchange factor 1 OS=Homo sapiens OX=9606 GN=ARHGEF1","ARHGEF1",102.43,42.433,15,12,13,12,0.979,0.92,0.828,1.114,1.087,1.02,1.181,0.0388,"nucleus\r","GO:0044700 single organism signaling; GO:0051093 negative regulation of developmental process; GO:0010941 regulation of cell death; GO:0023051 regulation of signaling; GO:0051129 negative regulation of cellular component organization; GO:0048869 cellular developmental process; GO:0022008 neurogenesis; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0044093 positive regulation of molecular function; GO:0007266 Rho protein signal transduction; GO:0050771 negative regulation of axonogenesis; GO:0045596 negative regulation of cell differentiation; GO:0051056 regulation of small GTPase mediated signal transduction; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0007264 small GTPase mediated signal transduction; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0010942 positive regulation of cell death; GO:0050768 negative regulation of neurogenesis; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:0045664 regulation of neuron differentiation; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0045665 negative regulation of neuron differentiation; GO:0065009 regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0010721 negative regulation of cell development; GO:0048856 anatomical structure development; GO:0010975 regulation of neuron projection development; GO:0043068 positive regulation of programmed cell death; GO:0007265 Ras protein signal transduction; GO:2000026 regulation of multicellular organismal development; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0043067 regulation of programmed cell death; GO:0043065 positive regulation of apoptotic process; GO:0046578 regulation of Ras protein signal transduction; GO:0031344 regulation of cell projection organization; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:0030154 cell differentiation; GO:0051345 positive regulation of hydrolase activity; GO:0051961 negative regulation of nervous system development; GO:0031345 negative regulation of cell projection organization; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0010771 negative regulation of cell morphogenesis involved in differentiation; GO:1902531 regulation of intracellular signal transduction; GO:0035556 intracellular signal transduction; GO:0043547 positive regulation of GTPase activity; GO:0048731 system development; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0008283 cell proliferation; GO:0010977 negative regulation of neuron projection development; GO:0048518 positive regulation of biological process; GO:0050770 regulation of axonogenesis; GO:0043085 positive regulation of catalytic activity; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0051128 regulation of cellular component organization; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:0035023 regulation of Rho protein signal transduction; GO:0050793 regulation of developmental process; GO:0022604 regulation of cell morphogenesis; GO:0042981 regulation of apoptotic process; GO:0050767 regulation of neurogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0071944 cell periphery; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005886 plasma membrane; GO:0044444 cytoplasmic part; ","GO:0003723 RNA binding; GO:0005085 guanyl-nucleotide exchange factor activity; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0030695 GTPase regulator activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005088 Ras guanyl-nucleotide exchange factor activity; GO:0008047 enzyme activator activity; GO:0005096 GTPase activator activity; GO:0005089 Rho guanyl-nucleotide exchange factor activity; ","K12330","ARHGEF1; Rho guanine nucleotide exchange factor 1","hsa04611 Platelet activation - Homo sapiens (human); hsa05205 Proteoglycans in cancer - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa04928 Parathyroid hormone synthesis, secretion and action - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa04270 Vascular smooth muscle contraction - Homo sapiens (human); ","IPR016137; IPR011993; IPR015212; IPR000219; IPR001849; ","RGS domain; PH domain-like; Regulator of G protein signalling-like domain; Dbl homology (DH) domain; Pleckstrin homology domain; \r"]
["Q92900","Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1","UPF1",124.34,38.934,9.9,10,10,10,1.033,0.9,0.941,1.055,1.023,1.026,1.08,0.133,"cytoplasm\r","GO:0050658 RNA transport; GO:0065008 regulation of biological quality; GO:0010608 posttranscriptional regulation of gene expression; GO:0051169 nuclear transport; GO:0070555 response to interleukin-1; GO:0071345 cellular response to cytokine stimulus; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0009607 response to biotic stimulus; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0033260 nuclear DNA replication; GO:0015931 nucleobase-containing compound transport; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0043170 macromolecule metabolic process; GO:0008104 protein localization; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0034249 negative regulation of cellular amide metabolic process; GO:0071044 histone mRNA catabolic process; GO:0031323 regulation of cellular metabolic process; GO:0006611 protein export from nucleus; GO:0051704 multi-organism process; GO:0071396 cellular response to lipid; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0009048 dosage compensation by inactivation of X chromosome; GO:0044710 single-organism metabolic process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006913 nucleocytoplasmic transport; GO:0032200 telomere organization; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0016071 mRNA metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0046907 intracellular transport; GO:0006260 DNA replication; GO:0006259 DNA metabolic process; GO:0051028 mRNA transport; GO:1901700 response to oxygen-containing compound; GO:0017148 negative regulation of translation; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0060249 anatomical structure homeostasis; GO:0051236 establishment of RNA localization; GO:0043487 regulation of RNA stability; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0009896 positive regulation of catabolic process; GO:0044248 cellular catabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0061013 regulation of mRNA catabolic process; GO:0034613 cellular protein localization; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0009617 response to bacterium; GO:0051254 positive regulation of RNA metabolic process; GO:0006950 response to stress; GO:0032496 response to lipopolysaccharide; GO:0006403 RNA localization; GO:0006405 RNA export from nucleus; GO:0071702 organic substance transport; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0006974 cellular response to DNA damage stimulus; GO:0034248 regulation of cellular amide metabolic process; GO:0045184 establishment of protein localization; GO:0009890 negative regulation of biosynthetic process; GO:1903311 regulation of mRNA metabolic process; GO:0051276 chromosome organization; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0061158 3'-UTR-mediated mRNA destabilization; GO:0071219 cellular response to molecule of bacterial origin; GO:0051179 localization; GO:0000723 telomere maintenance; GO:0031331 positive regulation of cellular catabolic process; GO:0006449 regulation of translational termination; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0051168 nuclear export; GO:0051234 establishment of localization; GO:0071427 mRNA-containing ribonucleoprotein complex export from nucleus; GO:0051649 establishment of localization in cell; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0009893 positive regulation of metabolic process; GO:0050657 nucleic acid transport; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:1901361 organic cyclic compound catabolic process; GO:0006261 DNA-dependent DNA replication; GO:0033036 macromolecule localization; GO:0070887 cellular response to chemical stimulus; GO:0008334 histone mRNA metabolic process; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0034097 response to cytokine; GO:0002237 response to molecule of bacterial origin; GO:0019725 cellular homeostasis; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0010605 negative regulation of macromolecule metabolic process; GO:1903313 positive regulation of mRNA metabolic process; GO:0071166 ribonucleoprotein complex localization; GO:0006401 RNA catabolic process; GO:0016070 RNA metabolic process; GO:1902589 single-organism organelle organization; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0090304 nucleic acid metabolic process; GO:0019222 regulation of metabolic process; GO:0043244 regulation of protein complex disassembly; GO:0032201 telomere maintenance via semi-conservative replication; GO:0050779 RNA destabilization; GO:0016043 cellular component organization; GO:0071222 cellular response to lipopolysaccharide; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0071347 cellular response to interleukin-1; GO:0031324 negative regulation of cellular metabolic process; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0033993 response to lipid; GO:0071216 cellular response to biotic stimulus; GO:0061014 positive regulation of mRNA catabolic process; GO:0007549 dosage compensation; GO:0006886 intracellular protein transport; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044786 cell cycle DNA replication; GO:0006406 mRNA export from nucleus; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay; GO:0043488 regulation of mRNA stability; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0061157 mRNA destabilization; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0040029 regulation of gene expression, epigenetic; GO:0006281 DNA repair; GO:0070727 cellular macromolecule localization; GO:1901701 cellular response to oxygen-containing compound; GO:0071426 ribonucleoprotein complex export from nucleus; GO:0034645 cellular macromolecule biosynthetic process; GO:0051246 regulation of protein metabolic process; GO:0006417 regulation of translation; GO:0009057 macromolecule catabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0010467 gene expression; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0022402 cell cycle process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0051128 regulation of cellular component organization; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0071705 nitrogen compound transport; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:0046700 heterocycle catabolic process; ","GO:0000784 nuclear chromosome, telomeric region; GO:0000781 chromosome, telomeric region; GO:0000932 P-body; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044454 nuclear chromosome part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005681 spliceosomal complex; GO:0005829 cytosol; GO:0044530 supraspliceosomal complex; GO:0043226 organelle; GO:0098687 chromosomal region; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0000785 chromatin; GO:0035770 ribonucleoprotein granule; GO:0000228 nuclear chromosome; GO:1990904 ribonucleoprotein complex; GO:0043234 protein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0035145 exon-exon junction complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0008026 ATP-dependent helicase activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0042162 telomeric DNA binding; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0003682 chromatin binding; GO:0016887 ATPase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0004004 ATP-dependent RNA helicase activity; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003677 DNA binding; GO:0003723 RNA binding; GO:0070035 purine NTP-dependent helicase activity; GO:0005524 ATP binding; GO:0004386 helicase activity; GO:0008186 RNA-dependent ATPase activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0008270 zinc ion binding; GO:0043565 sequence-specific DNA binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003724 RNA helicase activity; GO:0046914 transition metal ion binding; GO:0003676 nucleic acid binding; GO:0042623 ATPase activity, coupled; GO:0046872 metal ion binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; ","K14326","UPF1; regulator of nonsense transcripts 1 [EC:3.6.4.-]","hsa03015 mRNA surveillance pathway - Homo sapiens (human); hsa03013 RNA transport - Homo sapiens (human); ","IPR006935; IPR027417; IPR018999; ","\"Helicase/UvrB, N-terminal; P-loop containing nucleoside triphosphate hydrolase; RNA helicase UPF1, UPF2-interacting domain; \"\r"]
["Q92905","COP9 signalosome complex subunit 5 OS=Homo sapiens OX=9606 GN=COPS5","COPS5",37.578,29.797,29.6,8,10,8,0.99,0.982,0.94,0.997,1.017,1.007,1.037,0.0965,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0032872 regulation of stress-activated MAPK cascade; GO:0006518 peptide metabolic process; GO:0097659 nucleic acid-templated transcription; GO:0006289 nucleotide-excision repair; GO:0009891 positive regulation of biosynthetic process; GO:1903894 regulation of IRE1-mediated unfolded protein response; GO:1905897 regulation of response to endoplasmic reticulum stress; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044763 single-organism cellular process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0006810 transport; GO:1903506 regulation of nucleic acid-templated transcription; GO:0080135 regulation of cellular response to stress; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0000338 protein deneddylation; GO:0033554 cellular response to stress; GO:0006283 transcription-coupled nucleotide-excision repair; GO:0006259 DNA metabolic process; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0080134 regulation of response to stress; GO:1900101 regulation of endoplasmic reticulum unfolded protein response; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0009966 regulation of signal transduction; GO:0051254 positive regulation of RNA metabolic process; GO:1902531 regulation of intracellular signal transduction; GO:0006950 response to stress; GO:0016192 vesicle-mediated transport; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0006974 cellular response to DNA damage stimulus; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0051276 chromosome organization; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0051179 localization; GO:0031328 positive regulation of cellular biosynthetic process; GO:0043412 macromolecule modification; GO:0006887 exocytosis; GO:1901564 organonitrogen compound metabolic process; GO:0070646 protein modification by small protein removal; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0097734 extracellular exosome biogenesis; GO:0051234 establishment of localization; GO:2001141 regulation of RNA biosynthetic process; GO:0010646 regulation of cell communication; GO:0070302 regulation of stress-activated protein kinase signaling cascade; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0006413 translational initiation; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0006412 translation; GO:0051726 regulation of cell cycle; GO:0046328 regulation of JNK cascade; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0043043 peptide biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0070647 protein modification by small protein conjugation or removal; GO:0043603 cellular amide metabolic process; GO:0016070 RNA metabolic process; GO:0000715 nucleotide-excision repair, DNA damage recognition; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0032940 secretion by cell; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0036211 protein modification process; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0016579 protein deubiquitination; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0043408 regulation of MAPK cascade; GO:0034641 cellular nitrogen compound metabolic process; GO:0006508 proteolysis; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006355 regulation of transcription, DNA-templated; GO:0001932 regulation of protein phosphorylation; GO:0006807 nitrogen compound metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0006281 DNA repair; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0051246 regulation of protein metabolic process; GO:0006366 transcription from RNA polymerase II promoter; GO:0010467 gene expression; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0043604 amide biosynthetic process; GO:1990182 exosomal secretion; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0031410 cytoplasmic vesicle; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0008180 COP9 signalosome; GO:0005623 cell; GO:0044422 organelle part; GO:0070382 exocytic vesicle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0008021 synaptic vesicle; GO:0098793 presynapse; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0044456 synapse part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0045202 synapse; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0030133 transport vesicle; GO:0043234 protein complex; GO:0005852 eukaryotic translation initiation factor 3 complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0004843 thiol-dependent ubiquitin-specific protease activity; GO:0003723 RNA binding; GO:0008233 peptidase activity; GO:0043167 ion binding; GO:0019783 ubiquitin-like protein-specific protease activity; GO:0003743 translation initiation factor activity; GO:0008237 metallopeptidase activity; GO:0008234 cysteine-type peptidase activity; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0003712 transcription cofactor activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0008135 translation factor activity, RNA binding; GO:0036459 thiol-dependent ubiquitinyl hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0101005 ubiquitinyl hydrolase activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0003713 transcription coactivator activity; GO:0000988 transcription factor activity, protein binding; ","K09613",null,null,"IPR000555; ","JAB1/MPN/MOV34 metalloenzyme domain; \r"]
["Q92954","Proteoglycan 4 OS=Homo sapiens OX=9606 GN=PRG4","PRG4",151.06,4.8497,1.2,1,1,1,0.838,0.993,0.857,1.152,1.06,1.101,1.233,0.0224,"extracellular\r","GO:0006810 transport; GO:0016192 vesicle-mediated transport; GO:0044699 single-organism process; GO:0002376 immune system process; GO:0008283 cell proliferation; GO:0006898 receptor-mediated endocytosis; GO:0006955 immune response; GO:0050896 response to stimulus; GO:0006897 endocytosis; GO:0051179 localization; GO:0051234 establishment of localization; ","GO:0005576 extracellular region; ","GO:0030246 carbohydrate binding; GO:0038024 cargo receptor activity; GO:0005044 scavenger receptor activity; GO:0060089 molecular transducer activity; GO:0030247 polysaccharide binding; GO:0004872 receptor activity; GO:0001871 pattern binding; GO:0005488 binding; ",{"$nulls":3},"IPR000585; IPR020436; IPR001212; ","\"Hemopexin-like domain; Somatomedin B, chordata; Somatomedin B domain; \"\r"]
["Q92973","Transportin-1 OS=Homo sapiens OX=9606 GN=TNPO1","TNPO1",102.35,70.471,13.7,11,14,8,0.994,0.984,0.932,1.06,1.015,1.095,1.089,0.0451,"cytoplasm\r","GO:0098840 protein transport along microtubule; GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0006607 NLS-bearing protein import into nucleus; GO:0072594 establishment of protein localization to organelle; GO:0010608 posttranscriptional regulation of gene expression; GO:0017038 protein import; GO:0060271 cilium assembly; GO:0044699 single-organism process; GO:0051169 nuclear transport; GO:0044764 multi-organism cellular process; GO:0044782 cilium organization; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0010970 transport along microtubule; GO:0051649 establishment of localization in cell; GO:0022607 cellular component assembly; GO:0033365 protein localization to organelle; GO:0044419 interspecies interaction between organisms; GO:0006606 protein import into nucleus; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0044765 single-organism transport; GO:0010468 regulation of gene expression; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0006610 ribosomal protein import into nucleus; GO:0035735 intraciliary transport involved in cilium assembly; GO:0051704 multi-organism process; GO:1902582 single-organism intracellular transport; GO:0006810 transport; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0030030 cell projection organization; GO:0019222 regulation of metabolic process; GO:0006913 nucleocytoplasmic transport; GO:0099118 microtubule-based protein transport; GO:0031503 protein complex localization; GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0000060 protein import into nucleus, translocation; GO:0060255 regulation of macromolecule metabolic process; GO:1902593 single-organism nuclear import; GO:0099111 microtubule-based transport; GO:0030705 cytoskeleton-dependent intracellular transport; GO:0043487 regulation of RNA stability; GO:1902578 single-organism localization; GO:0070925 organelle assembly; GO:0016032 viral process; GO:0006886 intracellular protein transport; GO:0044744 protein targeting to nucleus; GO:1902580 single-organism cellular localization; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0071702 organic substance transport; GO:0042073 intraciliary transport; GO:0043488 regulation of mRNA stability; GO:0007017 microtubule-based process; GO:0030031 cell projection assembly; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0007018 microtubule-based movement; GO:0070727 cellular macromolecule localization; GO:0051170 nuclear import; GO:0006996 organelle organization; GO:0006928 movement of cell or subcellular component; GO:0051179 localization; GO:0034504 protein localization to nucleus; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0031965 nuclear membrane; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0005929 cilium; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0005635 nuclear envelope; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0031975 envelope; GO:0034399 nuclear periphery; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0031267 small GTPase binding; GO:0003723 RNA binding; GO:0008565 protein transporter activity; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0033218 amide binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0005048 signal sequence binding; GO:0017016 Ras GTPase binding; GO:0042277 peptide binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0008139 nuclear localization sequence binding; GO:0008536 Ran GTPase binding; GO:0051020 GTPase binding; GO:0019899 enzyme binding; GO:0005215 transporter activity; ","K18752",null,null,"IPR001494; IPR011989; IPR016024; ","\"Importin-beta, N-terminal domain; Armadillo-like helical; Armadillo-type fold; \"\r"]
["Q93008","Probable ubiquitin carboxyl-terminal hydrolase FAF-X OS=Homo sapiens OX=9606 GN=USP9X","USP9X",292.28,66.122,6.3,14,18,14,0.985,0.985,1.006,0.998,0.98,1.031,1.011,0.545,"plasma membrane\r","GO:0044700 single organism signaling; GO:0007166 cell surface receptor signaling pathway; GO:0022414 reproductive process; GO:0032989 cellular component morphogenesis; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0030509 BMP signaling pathway; GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0044702 single organism reproductive process; GO:0009719 response to endogenous stimulus; GO:0070848 response to growth factor; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0000278 mitotic cell cycle; GO:0007059 chromosome segregation; GO:0080090 regulation of primary metabolic process; GO:0016049 cell growth; GO:0048699 generation of neurons; GO:0000122 negative regulation of transcription from RNA polymerase II promoter; GO:0019953 sexual reproduction; GO:0044763 single-organism cellular process; GO:0048812 neuron projection morphogenesis; GO:0048870 cell motility; GO:0031323 regulation of cellular metabolic process; GO:0071559 response to transforming growth factor beta; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0000902 cell morphogenesis; GO:1901575 organic substance catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0030163 protein catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0051301 cell division; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0048609 multicellular organismal reproductive process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0000003 reproduction; GO:0044707 single-multicellular organism process; GO:0044267 cellular protein metabolic process; GO:1990138 neuron projection extension; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:1903047 mitotic cell cycle process; GO:0045892 negative regulation of transcription, DNA-templated; GO:0009653 anatomical structure morphogenesis; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0009889 regulation of biosynthetic process; GO:0007409 axonogenesis; GO:0044248 cellular catabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0016567 protein ubiquitination; GO:0048731 system development; GO:0007179 transforming growth factor beta receptor signaling pathway; GO:0060560 developmental growth involved in morphogenesis; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0030182 neuron differentiation; GO:0009890 negative regulation of biosynthetic process; GO:0032446 protein modification by small protein conjugation; GO:0006996 organelle organization; GO:0006928 movement of cell or subcellular component; GO:0000280 nuclear division; GO:0051179 localization; GO:0048589 developmental growth; GO:0043412 macromolecule modification; GO:0040007 growth; GO:0070646 protein modification by small protein removal; GO:0051674 localization of cell; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0007067 mitotic nuclear division; GO:0071560 cellular response to transforming growth factor beta stimulus; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0071363 cellular response to growth factor stimulus; GO:0051253 negative regulation of RNA metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0032990 cell part morphogenesis; GO:0048858 cell projection morphogenesis; GO:0001764 neuron migration; GO:0070887 cellular response to chemical stimulus; GO:0007167 enzyme linked receptor protein signaling pathway; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0032502 developmental process; GO:0048675 axon extension; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0030030 cell projection organization; GO:1902679 negative regulation of RNA biosynthetic process; GO:0019222 regulation of metabolic process; GO:0040011 locomotion; GO:0071772 response to BMP; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0016477 cell migration; GO:0016043 cellular component organization; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0007292 female gamete generation; GO:0060255 regulation of macromolecule metabolic process; GO:0048285 organelle fission; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0016579 protein deubiquitination; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0071704 organic substance metabolic process; GO:0000904 cell morphogenesis involved in differentiation; GO:0030154 cell differentiation; GO:0006508 proteolysis; GO:0071773 cellular response to BMP stimulus; GO:0009987 cellular process; GO:0043632 modification-dependent macromolecule catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0019941 modification-dependent protein catabolic process; GO:0010629 negative regulation of gene expression; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0031175 neuron projection development; GO:0051252 regulation of RNA metabolic process; GO:0007276 gamete generation; GO:0032504 multicellular organism reproduction; GO:0061564 axon development; GO:0048588 developmental cell growth; GO:0044767 single-organism developmental process; GO:0071495 cellular response to endogenous stimulus; GO:0009057 macromolecule catabolic process; GO:0044703 multi-organism reproductive process; GO:0022402 cell cycle process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0042995 cell projection; GO:0005622 intracellular; GO:0044464 cell part; GO:0005737 cytoplasm; GO:0043005 neuron projection; GO:0044424 intracellular part; GO:0030426 growth cone; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0030427 site of polarized growth; GO:0005623 cell; GO:0097458 neuron part; GO:0044444 cytoplasmic part; ","GO:0004175 endopeptidase activity; GO:0008233 peptidase activity; GO:0036459 thiol-dependent ubiquitinyl hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0019783 ubiquitin-like protein-specific protease activity; GO:0101005 ubiquitinyl hydrolase activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0070410 co-SMAD binding; GO:0008234 cysteine-type peptidase activity; GO:0004197 cysteine-type endopeptidase activity; GO:0046332 SMAD binding; ","K11840",null,null,"IPR011989; IPR001394; IPR028889; IPR016024; ","\"Armadillo-like helical; Peptidase C19, ubiquitin carboxyl-terminal hydrolase; Ubiquitin specific protease domain; Armadillo-type fold; \"\r"]
["Q93045","Stathmin-2 OS=Homo sapiens OX=9606 GN=STMN2","STMN2",20.828,4.6475,15.1,4,10,1,0.981,0.953,0.852,1.092,1.058,1.068,1.155,0.0295,"cytoplasm\r","GO:0051093 negative regulation of developmental process; GO:0045666 positive regulation of neuron differentiation; GO:0031111 negative regulation of microtubule polymerization or depolymerization; GO:0043243 positive regulation of protein complex disassembly; GO:0048869 cellular developmental process; GO:0051129 negative regulation of cellular component organization; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0051241 negative regulation of multicellular organismal process; GO:0031110 regulation of microtubule polymerization or depolymerization; GO:0071363 cellular response to growth factor stimulus; GO:0031117 positive regulation of microtubule depolymerization; GO:0051130 positive regulation of cellular component organization; GO:0051240 positive regulation of multicellular organismal process; GO:0032271 regulation of protein polymerization; GO:0009719 response to endogenous stimulus; GO:0070848 response to growth factor; GO:0051493 regulation of cytoskeleton organization; GO:0010720 positive regulation of cell development; GO:0045596 negative regulation of cell differentiation; GO:0031333 negative regulation of protein complex assembly; GO:0070887 cellular response to chemical stimulus; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0031346 positive regulation of cell projection organization; GO:0048699 generation of neurons; GO:0051494 negative regulation of cytoskeleton organization; GO:0051962 positive regulation of nervous system development; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0031113 regulation of microtubule polymerization; GO:0007026 negative regulation of microtubule depolymerization; GO:1901881 positive regulation of protein depolymerization; GO:0031114 regulation of microtubule depolymerization; GO:0032501 multicellular organismal process; GO:0032886 regulation of microtubule-based process; GO:0050768 negative regulation of neurogenesis; GO:0010639 negative regulation of organelle organization; GO:0043254 regulation of protein complex assembly; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0010638 positive regulation of organelle organization; GO:0045664 regulation of neuron differentiation; GO:0043242 negative regulation of protein complex disassembly; GO:0031112 positive regulation of microtubule polymerization or depolymerization; GO:1902904 negative regulation of supramolecular fiber organization; GO:0045665 negative regulation of neuron differentiation; GO:1902905 positive regulation of supramolecular fiber organization; GO:0043244 regulation of protein complex disassembly; GO:0010721 negative regulation of cell development; GO:0051094 positive regulation of developmental process; GO:0048856 anatomical structure development; GO:0010975 regulation of neuron projection development; GO:1902903 regulation of supramolecular fiber organization; GO:2000026 regulation of multicellular organismal development; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0071310 cellular response to organic substance; GO:0044087 regulation of cellular component biogenesis; GO:0031344 regulation of cell projection organization; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0045597 positive regulation of cell differentiation; GO:0051239 regulation of multicellular organismal process; GO:0031115 negative regulation of microtubule polymerization; GO:1901880 negative regulation of protein depolymerization; GO:0030154 cell differentiation; GO:0051961 negative regulation of nervous system development; GO:0031345 negative regulation of cell projection organization; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0070507 regulation of microtubule cytoskeleton organization; GO:1990089 response to nerve growth factor; GO:0051495 positive regulation of cytoskeleton organization; GO:1990090 cellular response to nerve growth factor stimulus; GO:0048731 system development; GO:0051960 regulation of nervous system development; GO:0060284 regulation of cell development; GO:1901879 regulation of protein depolymerization; GO:0033043 regulation of organelle organization; GO:0010977 negative regulation of neuron projection development; GO:0010033 response to organic substance; GO:0048518 positive regulation of biological process; GO:0010976 positive regulation of neuron projection development; GO:0071495 cellular response to endogenous stimulus; GO:0044767 single-organism developmental process; GO:0050769 positive regulation of neurogenesis; GO:0051128 regulation of cellular component organization; GO:0032272 negative regulation of protein polymerization; GO:0050793 regulation of developmental process; GO:0050767 regulation of neurogenesis; GO:0065007 biological regulation; ","GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0031252 cell leading edge; GO:0016020 membrane; GO:0042995 cell projection; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0043025 neuronal cell body; GO:0012505 endomembrane system; GO:0030426 growth cone; GO:0044424 intracellular part; GO:0044463 cell projection part; GO:0030427 site of polarized growth; GO:0005623 cell; GO:0043231 intracellular membrane-bounded organelle; GO:0030424 axon; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0044464 cell part; GO:0005622 intracellular; GO:0030027 lamellipodium; GO:0048471 perinuclear region of cytoplasm; GO:0043005 neuron projection; GO:0005768 endosome; GO:0044297 cell body; GO:0005794 Golgi apparatus; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0044444 cytoplasmic part; ","GO:0015631 tubulin binding; GO:0005515 protein binding; GO:0008092 cytoskeletal protein binding; GO:0048306 calcium-dependent protein binding; GO:0005488 binding; "]
["Q93084","Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 OS=Homo sapiens OX=9606 GN=ATP2A3","ATP2A3",113.98,52.841,12.6,11,18,5,1.186,1.18,1.136,0.837,0.838,0.871,0.727,7.59e-05,"plasma membrane\r","GO:0070588 calcium ion transmembrane transport; GO:0072511 divalent inorganic cation transport; GO:0098655 cation transmembrane transport; GO:0034220 ion transmembrane transport; GO:0098660 inorganic ion transmembrane transport; GO:0090662 ATP hydrolysis coupled transmembrane transport; GO:0030001 metal ion transport; GO:1903522 regulation of blood circulation; GO:0023051 regulation of signaling; GO:0008016 regulation of heart contraction; GO:0051239 regulation of multicellular organismal process; GO:0051234 establishment of localization; GO:1903779 regulation of cardiac conduction; GO:0006810 transport; GO:0055085 transmembrane transport; GO:0050789 regulation of biological process; GO:0006812 cation transport; GO:0006816 calcium ion transport; GO:0006811 ion transport; GO:0044057 regulation of system process; GO:0099132 ATP hydrolysis coupled cation transmembrane transport; GO:0051179 localization; GO:0099131 ATP hydrolysis coupled ion transmembrane transport; GO:0098662 inorganic cation transmembrane transport; GO:0065007 biological regulation; GO:0070838 divalent metal ion transport; ","GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0016528 sarcoplasm; GO:0005623 cell; GO:0044422 organelle part; GO:0033017 sarcoplasmic reticulum membrane; GO:0031965 nuclear membrane; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0031094 platelet dense tubular network; GO:0005789 endoplasmic reticulum membrane; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0005635 nuclear envelope; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0016529 sarcoplasmic reticulum; GO:0012505 endomembrane system; GO:0031095 platelet dense tubular network membrane; GO:0016021 integral component of membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044432 endoplasmic reticulum part; GO:0031975 envelope; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0042625 ATPase coupled ion transmembrane transporter activity; GO:1901265 nucleoside phosphate binding; GO:0015399 primary active transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0016887 ATPase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0046873 metal ion transmembrane transporter activity; GO:0016462 pyrophosphatase activity; GO:0019829 cation-transporting ATPase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0043492 ATPase activity, coupled to movement of substances; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0022890 inorganic cation transmembrane transporter activity; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005215 transporter activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0022804 active transmembrane transporter activity; GO:0005524 ATP binding; GO:0015075 ion transmembrane transporter activity; GO:0022853 active ion transmembrane transporter activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity; GO:0015662 ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism; GO:0072509 divalent inorganic cation transmembrane transporter activity; GO:0097367 carbohydrate derivative binding; GO:0005388 calcium-transporting ATPase activity; GO:0042626 ATPase activity, coupled to transmembrane movement of substances; GO:0042623 ATPase activity, coupled; GO:0046872 metal ion binding; GO:0015085 calcium ion transmembrane transporter activity; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0008324 cation transmembrane transporter activity; GO:0022857 transmembrane transporter activity; GO:0036094 small molecule binding; ","K05853","ATP2A; Ca2+ transporting ATPase, sarcoplasmic/endoplasmic reticulum [EC:3.6.3.8]","hsa04260 Cardiac muscle contraction - Homo sapiens (human); hsa05010 Alzheimer's disease - Homo sapiens (human); hsa05414 Dilated cardiomyopathy (DCM) - Homo sapiens (human); hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human); hsa04972 Pancreatic secretion - Homo sapiens (human); hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human); hsa04020 Calcium signaling pathway - Homo sapiens (human); hsa04024 cAMP signaling pathway - Homo sapiens (human); hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human); hsa05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human); hsa05410 Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human); ","IPR023298; IPR004014; IPR008250; IPR023299; IPR006068; IPR023214; ","\"P-type ATPase,  transmembrane domain; Cation-transporting P-type ATPase, N-terminal; P-type ATPase, A  domain; P-type ATPase, cytoplasmic domain N; Cation-transporting P-type ATPase, C-terminal; HAD-like domain; \"\r"]
["Q969G3","SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Homo sapiens OX=9606 GN=SMARCE1","SMARCE1",46.649,16.982,11.9,5,7,4,1.01,0.959,1.008,1.064,0.973,0.994,1.018,0.611,"nucleus\r","GO:0048869 cellular developmental process; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0051253 negative regulation of RNA metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0043170 macromolecule metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0071824 protein-DNA complex subunit organization; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0006333 chromatin assembly or disassembly; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0031498 chromatin disassembly; GO:0044763 single-organism cellular process; GO:0043044 ATP-dependent chromatin remodeling; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0032501 multicellular organismal process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0006337 nucleosome disassembly; GO:1902679 negative regulation of RNA biosynthetic process; GO:0019222 regulation of metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0006325 chromatin organization; GO:0048856 anatomical structure development; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0034728 nucleosome organization; GO:0006338 chromatin remodeling; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0071704 organic substance metabolic process; GO:0045892 negative regulation of transcription, DNA-templated; GO:0030154 cell differentiation; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0016569 covalent chromatin modification; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0032986 protein-DNA complex disassembly; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0048731 system development; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0032984 macromolecular complex disassembly; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0009892 negative regulation of metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0009890 negative regulation of biosynthetic process; GO:0051276 chromosome organization; GO:0044767 single-organism developmental process; GO:0006996 organelle organization; GO:0022411 cellular component disassembly; GO:0031327 negative regulation of cellular biosynthetic process; GO:0043412 macromolecule modification; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0032991 macromolecular complex; GO:0017053 transcriptional repressor complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0070603 SWI/SNF superfamily-type complex; GO:0044422 organelle part; GO:0071565 nBAF complex; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044454 nuclear chromosome part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005694 chromosome; GO:0000790 nuclear chromatin; GO:0071564 npBAF complex; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0000785 chromatin; GO:0000228 nuclear chromosome; GO:0043234 protein complex; GO:0090544 BAF-type complex; GO:0016514 SWI/SNF complex; GO:0044428 nuclear part; ","GO:0003677 DNA binding; GO:0003723 RNA binding; GO:0047485 protein N-terminus binding; GO:0005102 receptor binding; GO:0005515 protein binding; GO:0003682 chromatin binding; GO:0003712 transcription cofactor activity; GO:0008080 N-acetyltransferase activity; GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups; GO:0016407 acetyltransferase activity; GO:0016410 N-acyltransferase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016746 transferase activity, transferring acyl groups; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016922 ligand-dependent nuclear receptor binding; GO:0003676 nucleic acid binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0003713 transcription coactivator activity; GO:0000988 transcription factor activity, protein binding; GO:0016740 transferase activity; ","K11651","SMARCE1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E, member 1","hsa05225 Hepatocellular carcinoma - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); ","IPR009071; ","High mobility group box domain; \r"]
["Q969N2","GPI transamidase component PIG-T OS=Homo sapiens OX=9606 GN=PIGT","PIGT",65.699,5.0081,3.8,2,2,2,0.962,1.04,0.967,1.032,0.972,1.037,1.024,0.5,"plasma membrane\r","GO:0046486 glycerolipid metabolic process; GO:0070997 neuron death; GO:0006643 membrane lipid metabolic process; GO:0048869 cellular developmental process; GO:0008654 phospholipid biosynthetic process; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0042157 lipoprotein metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0008610 lipid biosynthetic process; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0006915 apoptotic process; GO:0006650 glycerophospholipid metabolic process; GO:0046488 phosphatidylinositol metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0042158 lipoprotein biosynthetic process; GO:0006629 lipid metabolic process; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0051402 neuron apoptotic process; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0006664 glycolipid metabolic process; GO:0032501 multicellular organismal process; GO:0090407 organophosphate biosynthetic process; GO:0044710 single-organism metabolic process; GO:0046474 glycerophospholipid biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0006497 protein lipidation; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0006506 GPI anchor biosynthetic process; GO:0009247 glycolipid biosynthetic process; GO:0044707 single-multicellular organism process; GO:1903509 liposaccharide metabolic process; GO:0006661 phosphatidylinositol biosynthetic process; GO:0044267 cellular protein metabolic process; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0016255 attachment of GPI anchor to protein; GO:0006505 GPI anchor metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0007275 multicellular organism development; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0046467 membrane lipid biosynthetic process; GO:0044711 single-organism biosynthetic process; GO:0048731 system development; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0045017 glycerolipid biosynthetic process; GO:0030182 neuron differentiation; GO:0034645 cellular macromolecule biosynthetic process; GO:0008219 cell death; GO:0006793 phosphorus metabolic process; GO:0044767 single-organism developmental process; GO:0019637 organophosphate metabolic process; GO:0006644 phospholipid metabolic process; GO:0012501 programmed cell death; GO:0043412 macromolecule modification; ","GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:1902494 catalytic complex; GO:0044432 endoplasmic reticulum part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0031227 intrinsic component of endoplasmic reticulum membrane; GO:0042765 GPI-anchor transamidase complex; GO:0030176 integral component of endoplasmic reticulum membrane; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0003923 GPI-anchor transamidase activity; GO:0016787 hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; ","K05292","PIGT; phosphatidylinositol glycan, class T","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis - Homo sapiens (human); "]
["Q969X1","Protein lifeguard 3 OS=Homo sapiens OX=9606 GN=TMBIM1","TMBIM1",34.607,35.557,4.8,2,3,2,0.951,0.982,0.914,1.066,1.064,1.027,1.109,0.0125,"plasma membrane\r","GO:0010941 regulation of cell death; GO:0045321 leukocyte activation; GO:0009968 negative regulation of signal transduction; GO:0090005 negative regulation of establishment of protein localization to plasma membrane; GO:0051129 negative regulation of cellular component organization; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0034103 regulation of tissue remodeling; GO:0051234 establishment of localization; GO:2001233 regulation of apoptotic signaling pathway; GO:1903729 regulation of plasma membrane organization; GO:1904375 regulation of protein localization to cell periphery; GO:0010646 regulation of cell communication; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:1905476 negative regulation of protein localization to membrane; GO:0002443 leukocyte mediated immunity; GO:1903828 negative regulation of cellular protein localization; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0043086 negative regulation of catalytic activity; GO:0002444 myeloid leukocyte mediated immunity; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0050790 regulation of catalytic activity; GO:0032940 secretion by cell; GO:1902044 regulation of Fas signaling pathway; GO:0048583 regulation of response to stimulus; GO:2001236 regulation of extrinsic apoptotic signaling pathway; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0043299 leukocyte degranulation; GO:0060548 negative regulation of cell death; GO:0050794 regulation of cellular process; GO:0043069 negative regulation of programmed cell death; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:1902045 negative regulation of Fas signaling pathway; GO:1903076 regulation of protein localization to plasma membrane; GO:0043067 regulation of programmed cell death; GO:1904376 negative regulation of protein localization to cell periphery; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:0070201 regulation of establishment of protein localization; GO:0060341 regulation of cellular localization; GO:1903077 negative regulation of protein localization to plasma membrane; GO:1905475 regulation of protein localization to membrane; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0043066 negative regulation of apoptotic process; GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors; GO:0032880 regulation of protein localization; GO:0036230 granulocyte activation; GO:0090003 regulation of establishment of protein localization to plasma membrane; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:2000504 positive regulation of blood vessel remodeling; GO:0034105 positive regulation of tissue remodeling; GO:0016192 vesicle-mediated transport; GO:2001237 negative regulation of extrinsic apoptotic signaling pathway; GO:0002376 immune system process; GO:0048585 negative regulation of response to stimulus; GO:0043312 neutrophil degranulation; GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; GO:0048518 positive regulation of biological process; GO:0002263 cell activation involved in immune response; GO:0002366 leukocyte activation involved in immune response; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:0060312 regulation of blood vessel remodeling; GO:0022603 regulation of anatomical structure morphogenesis; GO:0001775 cell activation; GO:1904950 negative regulation of establishment of protein localization; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0006955 immune response; GO:0050793 regulation of developmental process; GO:0042981 regulation of apoptotic process; GO:1903827 regulation of cellular protein localization; GO:0006887 exocytosis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005765 lysosomal membrane; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0035579 specific granule membrane; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0010008 endosome membrane; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0098852 lytic vacuole membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0030667 secretory granule membrane; GO:0042581 specific granule; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005123 death receptor binding; GO:0005102 receptor binding; GO:0032813 tumor necrosis factor receptor superfamily binding; GO:0005488 binding; GO:0005126 cytokine receptor binding; ","K06890"]
["Q969Z0","FAST kinase domain-containing protein 4 OS=Homo sapiens OX=9606 GN=TBRG4","TBRG4",70.737,2.5263,1.6,1,1,1,1.073,1.192,1.122,0.911,0.889,0.84,0.779,0.00304,"mitochondria\r","GO:0050794 regulation of cellular process; GO:0016310 phosphorylation; GO:0045786 negative regulation of cell cycle; GO:0042127 regulation of cell proliferation; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0006468 protein phosphorylation; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0051726 regulation of cell cycle; GO:0009987 cellular process; GO:0007050 cell cycle arrest; GO:0055114 oxidation-reduction process; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0045333 cellular respiration; GO:0050789 regulation of biological process; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0022402 cell cycle process; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:0007049 cell cycle; GO:0008284 positive regulation of cell proliferation; GO:0065007 biological regulation; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0016301 kinase activity; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0003824 catalytic activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0004672 protein kinase activity; GO:0016740 transferase activity; GO:0016772 transferase activity, transferring phosphorus-containing groups; ",{"$nulls":3},"IPR013584; IPR013579; IPR010622; ","\"RAP domain; FAST kinase-like protein, subdomain 2; FAST kinase leucine-rich; \"\r"]
["Q96A00","Protein phosphatase 1 regulatory subunit 14A OS=Homo sapiens OX=9606 GN=PPP1R14A","PPP1R14A",16.693,12.014,10.9,1,2,1,1.184,1.099,1.172,0.839,0.862,0.869,0.744,0.000322,"mitochondria\r","GO:0050794 regulation of cellular process; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0035690 cellular response to drug; GO:0051174 regulation of phosphorus metabolic process; GO:0043086 negative regulation of catalytic activity; GO:0050896 response to stimulus; GO:0031323 regulation of cellular metabolic process; GO:0042493 response to drug; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0050790 regulation of catalytic activity; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0009987 cellular process; GO:0070887 cellular response to chemical stimulus; GO:0065007 biological regulation; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:0004864 protein phosphatase inhibitor activity; GO:0030234 enzyme regulator activity; GO:0019208 phosphatase regulator activity; GO:0019888 protein phosphatase regulator activity; GO:0098772 molecular function regulator; GO:0004857 enzyme inhibitor activity; GO:0019212 phosphatase inhibitor activity; ","K12328","PPP1R14A; protein phosphatase 1 regulatory subunit 14A","hsa04270 Vascular smooth muscle contraction - Homo sapiens (human); "]
["Q96A33","Coiled-coil domain-containing protein 47 OS=Homo sapiens OX=9606 GN=CCDC47","CCDC47",55.873,19.22,14.5,7,9,7,0.928,0.954,0.919,1.045,1.106,1.061,1.147,0.00254,"endoplasmic reticulum\r","GO:0044700 single organism signaling; GO:0001649 osteoblast differentiation; GO:0010256 endomembrane system organization; GO:0065008 regulation of biological quality; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0036503 ERAD pathway; GO:0044237 cellular metabolic process; GO:0009607 response to biotic stimulus; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0007154 cell communication; GO:0030433 ubiquitin-dependent ERAD pathway; GO:0055065 metal ion homeostasis; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0050801 ion homeostasis; GO:0055074 calcium ion homeostasis; GO:0001503 ossification; GO:0098771 inorganic ion homeostasis; GO:0044763 single-organism cellular process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:1901575 organic substance catabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0044710 single-organism metabolic process; GO:0030163 protein catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0048856 anatomical structure development; GO:0072507 divalent inorganic cation homeostasis; GO:0007029 endoplasmic reticulum organization; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0033554 cellular response to stress; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0034976 response to endoplasmic reticulum stress; GO:0044267 cellular protein metabolic process; GO:0009791 post-embryonic development; GO:0050896 response to stimulus; GO:0010498 proteasomal protein catabolic process; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:0071216 cellular response to biotic stimulus; GO:0055080 cation homeostasis; GO:0044248 cellular catabolic process; GO:0006508 proteolysis; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0006983 ER overload response; GO:0048878 chemical homeostasis; GO:0043632 modification-dependent macromolecule catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0006950 response to stress; GO:0019941 modification-dependent protein catabolic process; GO:0044712 single-organism catabolic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0006984 ER-nucleus signaling pathway; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0009057 macromolecule catabolic process; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0005791 rough endoplasmic reticulum; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0043167 ion binding; GO:0003676 nucleic acid binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0005509 calcium ion binding; "]
["Q96AB3","Isochorismatase domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ISOC2","ISOC2",22.337,50.133,24.9,3,4,3,1.087,1.01,0.972,1.034,0.91,1.003,0.96,0.464,"mitochondria\r","GO:0065008 regulation of biological quality; GO:0008152 metabolic process; GO:0031647 regulation of protein stability; GO:0031648 protein destabilization; GO:0065007 biological regulation; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; ","GO:0005515 protein binding; GO:0003824 catalytic activity; GO:0005488 binding; ",{"$nulls":3},"IPR000868; ","Isochorismatase-like; \r"]
["Q96AE4","Far upstream element-binding protein 1 OS=Homo sapiens OX=9606 GN=FUBP1","FUBP1",67.56,54.529,31.5,19,30,16,0.931,0.912,0.918,1.117,1.049,1.067,1.171,1.34E-3,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0006725 cellular aromatic compound metabolic process; GO:0097659 nucleic acid-templated transcription; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0009893 positive regulation of metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0006355 regulation of transcription, DNA-templated; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0034645 cellular macromolecule biosynthetic process; GO:0090304 nucleic acid metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006351 transcription, DNA-templated; GO:0006366 transcription from RNA polymerase II promoter; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0010467 gene expression; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0065007 biological regulation; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003677 DNA binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0001071 nucleic acid binding transcription factor activity; GO:0003676 nucleic acid binding; GO:0003697 single-stranded DNA binding; GO:0005515 protein binding; GO:0003700 transcription factor activity, sequence-specific DNA binding; ","K13210",null,null,"IPR004087; IPR004088; IPR015096; ","\"K Homology domain; K Homology domain, type 1; Domain of unknown function DUF1897; \"\r"]
["Q96AQ6","Pre-B-cell leukemia transcription factor-interacting protein 1 OS=Homo sapiens OX=9606 GN=PBXIP1","PBXIP1",80.642,17.521,6.4,4,4,4,1.144,1.192,1.025,0.849,0.895,0.921,0.793,0.0106,"plasma membrane\r","GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0060255 regulation of macromolecule metabolic process; GO:0048869 cellular developmental process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044699 single-organism process; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0051253 negative regulation of RNA metabolic process; GO:0045892 negative regulation of transcription, DNA-templated; GO:2001141 regulation of RNA biosynthetic process; GO:0030154 cell differentiation; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0009987 cellular process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0006355 regulation of transcription, DNA-templated; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0010629 negative regulation of gene expression; GO:0044763 single-organism cellular process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0051252 regulation of RNA metabolic process; GO:0009892 negative regulation of metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0009890 negative regulation of biosynthetic process; GO:0050789 regulation of biological process; GO:0044767 single-organism developmental process; GO:1902679 negative regulation of RNA biosynthetic process; GO:0019222 regulation of metabolic process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0048856 anatomical structure development; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0005874 microtubule; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0099081 supramolecular polymer; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0005856 cytoskeleton; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0000989 transcription factor activity, transcription factor binding; GO:0005515 protein binding; GO:0003714 transcription corepressor activity; GO:0003712 transcription cofactor activity; GO:0000988 transcription factor activity, protein binding; GO:0005488 binding; "]
["Q96AY3","Peptidyl-prolyl cis-trans isomerase FKBP10 OS=Homo sapiens OX=9606 GN=FKBP10","FKBP10",64.244,63.008,19.8,10,15,9,1.311,1.229,1.188,0.734,0.798,0.76,0.615,2.04E-4,"extracellular\r","GO:0061077 chaperone-mediated protein folding; GO:0044267 cellular protein metabolic process; GO:0044238 primary metabolic process; GO:0018208 peptidyl-proline modification; GO:0000413 protein peptidyl-prolyl isomerization; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0006457 protein folding; GO:0018193 peptidyl-amino acid modification; GO:0008152 metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:0009987 cellular process; ","GO:0005788 endoplasmic reticulum lumen; GO:0043229 intracellular organelle; GO:0005783 endoplasmic reticulum; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044432 endoplasmic reticulum part; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003755 peptidyl-prolyl cis-trans isomerase activity; GO:0016853 isomerase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0008144 drug binding; GO:0005509 calcium ion binding; GO:0005528 FK506 binding; GO:0005527 macrolide binding; GO:0016859 cis-trans isomerase activity; ","K09575",null,null,"IPR002048; IPR011992; IPR001179; ","EF-hand domain; EF-hand domain pair; FKBP-type peptidyl-prolyl cis-trans isomerase domain; \r"]
["Q96BH1","E3 ubiquitin-protein ligase RNF25 OS=Homo sapiens OX=9606 GN=RNF25","RNF25",51.218,2.3622,2.2,1,1,1,1.074,0.906,0.985,1.013,1.052,0.976,1.026,0.638,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0009889 regulation of biosynthetic process; GO:0044093 positive regulation of molecular function; GO:0051171 regulation of nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009987 cellular process; GO:0010468 regulation of gene expression; GO:0006355 regulation of transcription, DNA-templated; GO:0031326 regulation of cellular biosynthetic process; GO:0016567 protein ubiquitination; GO:0080090 regulation of primary metabolic process; GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity; GO:0010556 regulation of macromolecule biosynthetic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0031323 regulation of cellular metabolic process; GO:0044238 primary metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0051092 positive regulation of NF-kappaB transcription factor activity; GO:0032446 protein modification by small protein conjugation; GO:0051090 regulation of sequence-specific DNA binding transcription factor activity; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0006464 cellular protein modification process; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0065007 biological regulation; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:0061630 ubiquitin protein ligase activity; GO:0046914 transition metal ion binding; GO:0019787 ubiquitin-like protein transferase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0004842 ubiquitin-protein transferase activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0051059 NF-kappaB binding; GO:0005515 protein binding; GO:0061659 ubiquitin-like protein ligase activity; GO:0008270 zinc ion binding; GO:0016740 transferase activity; GO:0008134 transcription factor binding; ","K10640",null,null,"IPR016135; IPR001841; IPR013083; IPR006575; ","\"Ubiquitin-conjugating enzyme/RWD-like; Zinc finger, RING-type; Zinc finger, RING/FYVE/PHD-type; RWD domain; \"\r"]
["Q96BJ8","Engulfment and cell motility protein 3 OS=Homo sapiens OX=9606 GN=ELMO3","ELMO3",81.466,10.737,3.8,2,2,2,1.04,0.905,0.745,1.046,1.132,1.13,1.23,0.098,"mitochondria\r","GO:0016477 cell migration; GO:0051674 localization of cell; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0048870 cell motility; GO:0006897 endocytosis; GO:0051234 establishment of localization; GO:0006909 phagocytosis; GO:0006810 transport; GO:1902578 single-organism localization; GO:0008219 cell death; GO:0006915 apoptotic process; GO:0006928 movement of cell or subcellular component; GO:0040011 locomotion; GO:0012501 programmed cell death; GO:0051179 localization; GO:0009987 cellular process; GO:0044765 single-organism transport; ","GO:0044424 intracellular part; GO:0005623 cell; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; ","GO:0019904 protein domain specific binding; GO:0005515 protein binding; GO:0017124 SH3 domain binding; GO:0005488 binding; ","K19241","ELMO3; engulfment and cell motility protein 3","hsa05100 Bacterial invasion of epithelial cells - Homo sapiens (human); hsa05131 Shigellosis - Homo sapiens (human); ","IPR006816; IPR011993; IPR024574; IPR016024; IPR001849; ","ELMO domain; PH domain-like; Domain of unknown function DUF3361; Armadillo-type fold; Pleckstrin homology domain; \r"]
["Q96C11","FGGY carbohydrate kinase domain-containing protein OS=Homo sapiens OX=9606 GN=FGGY","FGGY",59.992,2.7744,3.3,2,2,2,0.778,1.052,0.978,1.008,1.018,1.163,1.136,0.262,"cytoplasm\r","GO:0016310 phosphorylation; GO:0065008 regulation of biological quality; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0019725 cellular homeostasis; GO:0005975 carbohydrate metabolic process; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0060249 anatomical structure homeostasis; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0008152 metabolic process; GO:0006793 phosphorus metabolic process; GO:0070050 neuron cellular homeostasis; GO:0009987 cellular process; GO:0065007 biological regulation; ","GO:0005623 cell; ","GO:0016301 kinase activity; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0003824 catalytic activity; GO:0016740 transferase activity; GO:0016772 transferase activity, transferring phosphorus-containing groups; ",{"$nulls":3},"IPR018484; IPR018485; ","\"Carbohydrate kinase, FGGY, N-terminal; Carbohydrate kinase, FGGY, C-terminal; \"\r"]
["Q96C23","Aldose 1-epimerase OS=Homo sapiens OX=9606 GN=GALM","GALM",37.765,15.113,8.2,2,2,2,0.975,1.14,1.138,0.815,1.057,0.888,0.848,0.144,"cytoplasm\r","GO:0046365 monosaccharide catabolic process; GO:0044724 single-organism carbohydrate catabolic process; GO:0044712 single-organism catabolic process; GO:0044281 small molecule metabolic process; GO:0044699 single-organism process; GO:0044282 small molecule catabolic process; GO:0044238 primary metabolic process; GO:0005975 carbohydrate metabolic process; GO:0016052 carbohydrate catabolic process; GO:0071704 organic substance metabolic process; GO:0006006 glucose metabolic process; GO:1901575 organic substance catabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0008152 metabolic process; GO:0044710 single-organism metabolic process; GO:0005996 monosaccharide metabolic process; GO:0033499 galactose catabolic process via UDP-galactose; GO:0019388 galactose catabolic process; GO:0019320 hexose catabolic process; GO:0009056 catabolic process; GO:0006012 galactose metabolic process; GO:0019318 hexose metabolic process; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:0016853 isomerase activity; GO:0016854 racemase and epimerase activity; GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives; GO:0003824 catalytic activity; GO:0005488 binding; GO:0030246 carbohydrate binding; GO:0004034 aldose 1-epimerase activity; ","K01785","galM; aldose 1-epimerase [EC:5.1.3.3]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00052 Galactose metabolism - Homo sapiens (human); hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human); ","IPR011013; IPR014718; ","Galactose mutarotase-like domain; Glycoside hydrolase-type carbohydrate-binding; \r"]
["Q96C86","m7GpppX diphosphatase OS=Homo sapiens OX=9606 GN=DCPS","DCPS",38.608,45.141,29.4,8,9,8,1.104,0.981,1.005,1.007,0.976,0.965,0.954,0.296,"cyto_nucl\r","GO:0010941 regulation of cell death; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA; GO:1901361 organic cyclic compound catabolic process; GO:0043170 macromolecule metabolic process; GO:0070887 cellular response to chemical stimulus; GO:0006396 RNA processing; GO:0010468 regulation of gene expression; GO:0051716 cellular response to stimulus; GO:1901360 organic cyclic compound metabolic process; GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic; GO:0010605 negative regulation of macromolecule metabolic process; GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; GO:0006401 RNA catabolic process; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; GO:0090304 nucleic acid metabolic process; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0090305 nucleic acid phosphodiester bond hydrolysis; GO:0016071 mRNA metabolic process; GO:0060548 negative regulation of cell death; GO:0050794 regulation of cellular process; GO:0043069 negative regulation of programmed cell death; GO:0036245 cellular response to menadione; GO:0006725 cellular aromatic compound metabolic process; GO:0045292 mRNA cis splicing, via spliceosome; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0043067 regulation of programmed cell death; GO:1901700 response to oxygen-containing compound; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0009987 cellular process; GO:0008380 RNA splicing; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:1901655 cellular response to ketone; GO:0010629 negative regulation of gene expression; GO:0006807 nitrogen compound metabolic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0090501 RNA phosphodiester bond hydrolysis; GO:1901701 cellular response to oxygen-containing compound; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0009056 catabolic process; GO:0046700 heterocycle catabolic process; GO:1901654 response to ketone; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0000932 P-body; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0035770 ribonucleoprotein granule; GO:1990904 ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0030529 intracellular ribonucleoprotein complex; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0003723 RNA binding; GO:0000339 RNA cap binding; GO:0050072 m7G(5')pppN diphosphatase activity; GO:0000340 RNA 7-methylguanosine cap binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0004532 exoribonuclease activity; GO:0016788 hydrolase activity, acting on ester bonds; GO:0004518 nuclease activity; GO:0003676 nucleic acid binding; GO:0004527 exonuclease activity; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0004540 ribonuclease activity; ","K12584","DCPS; m7GpppX diphosphatase [EC:3.6.1.59]","hsa03018 RNA degradation - Homo sapiens (human); ","IPR011146; IPR011145; ","\"HIT-like domain; Scavenger mRNA decapping enzyme, N-terminal; \"\r"]
["Q96CG8","Collagen triple helix repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=CTHRC1","CTHRC1",26.224,40.904,22.6,5,13,5,1.211,1.228,1.264,0.717,0.803,0.753,0.614,0.000157,"extracellular\r","GO:0044700 single organism signaling; GO:0001738 morphogenesis of a polarized epithelium; GO:0007166 cell surface receptor signaling pathway; GO:0035148 tube formation; GO:0043009 chordate embryonic development; GO:0048562 embryonic organ morphogenesis; GO:0051240 positive regulation of multicellular organismal process; GO:0044093 positive regulation of molecular function; GO:0016055 Wnt signaling pathway; GO:0009790 embryo development; GO:0051099 positive regulation of binding; GO:0048598 embryonic morphogenesis; GO:0090596 sensory organ morphogenesis; GO:0033690 positive regulation of osteoblast proliferation; GO:0045667 regulation of osteoblast differentiation; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0001503 ossification; GO:0048699 generation of neurons; GO:0035239 tube morphogenesis; GO:0044763 single-organism cellular process; GO:0060828 regulation of canonical Wnt signaling pathway; GO:0048870 cell motility; GO:0007164 establishment of tissue polarity; GO:0032501 multicellular organismal process; GO:0048513 animal organ development; GO:0043583 ear development; GO:0007267 cell-cell signaling; GO:0045669 positive regulation of osteoblast differentiation; GO:0048583 regulation of response to stimulus; GO:0060071 Wnt signaling pathway, planar cell polarity pathway; GO:0009887 animal organ morphogenesis; GO:0051094 positive regulation of developmental process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0002009 morphogenesis of an epithelium; GO:0042127 regulation of cell proliferation; GO:0045778 positive regulation of ossification; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0045597 positive regulation of cell differentiation; GO:0051239 regulation of multicellular organismal process; GO:0009653 anatomical structure morphogenesis; GO:0060606 tube closure; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0016331 morphogenesis of embryonic epithelium; GO:0007275 multicellular organism development; GO:0001843 neural tube closure; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0009966 regulation of signal transduction; GO:0060562 epithelial tube morphogenesis; GO:0090103 cochlea morphogenesis; GO:0048731 system development; GO:0090177 establishment of planar polarity involved in neural tube closure; GO:0048839 inner ear development; GO:0030182 neuron differentiation; GO:0030111 regulation of Wnt signaling pathway; GO:0030278 regulation of ossification; GO:0006928 movement of cell or subcellular component; GO:0001736 establishment of planar polarity; GO:0007423 sensory organ development; GO:0051179 localization; GO:0046849 bone remodeling; GO:0050793 regulation of developmental process; GO:0008284 positive regulation of cell proliferation; GO:0001841 neural tube formation; GO:0060113 inner ear receptor cell differentiation; GO:0051674 localization of cell; GO:0009968 negative regulation of signal transduction; GO:0032092 positive regulation of protein binding; GO:0023051 regulation of signaling; GO:0048869 cellular developmental process; GO:0048666 neuron development; GO:0090090 negative regulation of canonical Wnt signaling pathway; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0042472 inner ear morphogenesis; GO:0033688 regulation of osteoblast proliferation; GO:0035567 non-canonical Wnt signaling pathway; GO:1905330 regulation of morphogenesis of an epithelium; GO:0048729 tissue morphogenesis; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0035295 tube development; GO:0030178 negative regulation of Wnt signaling pathway; GO:0009888 tissue development; GO:0051098 regulation of binding; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0198738 cell-cell signaling by wnt; GO:0050789 regulation of biological process; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0030030 cell projection organization; GO:0060122 inner ear receptor stereocilium organization; GO:0065009 regulation of molecular function; GO:0040011 locomotion; GO:0048856 anatomical structure development; GO:0090102 cochlea development; GO:2000026 regulation of multicellular organismal development; GO:0016477 cell migration; GO:0016043 cellular component organization; GO:0090175 regulation of establishment of planar polarity; GO:0048568 embryonic organ development; GO:0042249 establishment of planar polarity of embryonic epithelium; GO:0021915 neural tube development; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0072175 epithelial tube formation; GO:0043393 regulation of protein binding; GO:0030154 cell differentiation; GO:2000027 regulation of organ morphogenesis; GO:0043932 ossification involved in bone remodeling; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0048771 tissue remodeling; GO:0009792 embryo development ending in birth or egg hatching; GO:0042490 mechanoreceptor differentiation; GO:0048585 negative regulation of response to stimulus; GO:0048518 positive regulation of biological process; GO:0001838 embryonic epithelial tube formation; GO:0014020 primary neural tube formation; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0042471 ear morphogenesis; GO:0060119 inner ear receptor cell development; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0031012 extracellular matrix; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0005578 proteinaceous extracellular matrix; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0043234 protein complex; GO:0005623 cell; GO:0005576 extracellular region; GO:0005581 collagen trimer; ","GO:0001664 G-protein coupled receptor binding; GO:0005515 protein binding; GO:0005102 receptor binding; GO:0017147 Wnt-protein binding; GO:0005488 binding; GO:0005109 frizzled binding; "]
["Q96CN7","Isochorismatase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ISOC1","ISOC1",32.236,22.589,16.8,4,5,4,1.067,1.045,1.093,0.963,0.896,0.937,0.872,0.0052,"cytoplasm\r","GO:0008152 metabolic process; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0005777 peroxisome; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0005622 intracellular; GO:0044464 cell part; GO:0042579 microbody; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0003824 catalytic activity; GO:0005488 binding; ",{"$nulls":3},"IPR000868; ","Isochorismatase-like; \r"]
["Q96CV9","Optineurin OS=Homo sapiens OX=9606 GN=OPTN","OPTN",65.921,63.929,18.5,10,15,10,1.1,1.107,1.082,0.938,0.925,0.896,0.839,0.000318,"cytoplasm\r","GO:0044700 single organism signaling; GO:0098542 defense response to other organism; GO:0090002 establishment of protein localization to plasma membrane; GO:0031347 regulation of defense response; GO:0006914 autophagy; GO:0044237 cellular metabolic process; GO:0010821 regulation of mitochondrion organization; GO:0015031 protein transport; GO:0009607 response to biotic stimulus; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling; GO:0044770 cell cycle phase transition; GO:0033365 protein localization to organelle; GO:0008104 protein localization; GO:0044765 single-organism transport; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0072657 protein localization to membrane; GO:1903599 positive regulation of mitophagy; GO:0031329 regulation of cellular catabolic process; GO:0000301 retrograde transport, vesicle recycling within Golgi; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:1904923 regulation of mitophagy in response to mitochondrial depolarization; GO:0007009 plasma membrane organization; GO:0031323 regulation of cellular metabolic process; GO:0010506 regulation of autophagy; GO:0051704 multi-organism process; GO:0006810 transport; GO:0098779 positive regulation of macromitophagy in response to mitochondrial depolarization; GO:0016241 regulation of macroautophagy; GO:1902532 negative regulation of intracellular signal transduction; GO:0007030 Golgi organization; GO:0010508 positive regulation of autophagy; GO:0048583 regulation of response to stimulus; GO:0002833 positive regulation of response to biotic stimulus; GO:0016239 positive regulation of macroautophagy; GO:0000086 G2/M transition of mitotic cell cycle; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0033554 cellular response to stress; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:1903047 mitotic cell cycle process; GO:1990778 protein localization to cell periphery; GO:0023057 negative regulation of signaling; GO:0031349 positive regulation of defense response; GO:0010648 negative regulation of cell communication; GO:1902578 single-organism localization; GO:0009896 positive regulation of catabolic process; GO:0044248 cellular catabolic process; GO:1902580 single-organism cellular localization; GO:0034613 cellular protein localization; GO:0090150 establishment of protein localization to membrane; GO:0009966 regulation of signal transduction; GO:0009617 response to bacterium; GO:0044772 mitotic cell cycle phase transition; GO:1902531 regulation of intracellular signal transduction; GO:0006950 response to stress; GO:0043900 regulation of multi-organism process; GO:0016192 vesicle-mediated transport; GO:0032101 regulation of response to external stimulus; GO:0071702 organic substance transport; GO:0009892 negative regulation of metabolic process; GO:0045184 establishment of protein localization; GO:1901526 positive regulation of macromitophagy; GO:0072659 protein localization to plasma membrane; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0031325 positive regulation of cellular metabolic process; GO:0044839 cell cycle G2/M phase transition; GO:0048584 positive regulation of response to stimulus; GO:0006892 post-Golgi vesicle-mediated transport; GO:0051179 localization; GO:0061734 parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization; GO:1904415 regulation of xenophagy; GO:0010256 endomembrane system organization; GO:0072594 establishment of protein localization to organelle; GO:0009968 negative regulation of signal transduction; GO:0031331 positive regulation of cellular catabolic process; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0051130 positive regulation of cellular component organization; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0006893 Golgi to plasma membrane transport; GO:0032103 positive regulation of response to external stimulus; GO:1904417 positive regulation of xenophagy; GO:0033036 macromolecule localization; GO:0016236 macroautophagy; GO:0043902 positive regulation of multi-organism process; GO:0050829 defense response to Gram-negative bacterium; GO:0006891 intra-Golgi vesicle-mediated transport; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0050789 regulation of biological process; GO:0001920 negative regulation of receptor recycling; GO:0010638 positive regulation of organelle organization; GO:0019222 regulation of metabolic process; GO:0006952 defense response; GO:0016043 cellular component organization; GO:0002831 regulation of response to biotic stimulus; GO:0060255 regulation of macromolecule metabolic process; GO:0048193 Golgi vesicle transport; GO:0043207 response to external biotic stimulus; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0090161 Golgi ribbon formation; GO:1904925 positive regulation of mitophagy in response to mitochondrial depolarization; GO:0006886 intracellular protein transport; GO:0043001 Golgi to plasma membrane protein transport; GO:0009987 cellular process; GO:0098780 response to mitochondrial depolarisation; GO:0001919 regulation of receptor recycling; GO:1901524 regulation of macromitophagy; GO:0034067 protein localization to Golgi apparatus; GO:0098876 vesicle-mediated transport to the plasma membrane; GO:0042742 defense response to bacterium; GO:0072600 establishment of protein localization to Golgi; GO:0033043 regulation of organelle organization; GO:0044802 single-organism membrane organization; GO:0048585 negative regulation of response to stimulus; GO:0048518 positive regulation of biological process; GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling; GO:0010822 positive regulation of mitochondrion organization; GO:0051641 cellular localization; GO:0070727 cellular macromolecule localization; GO:1903146 regulation of mitophagy; GO:0008219 cell death; GO:0022402 cell cycle process; GO:0051128 regulation of cellular component organization; GO:0000042 protein targeting to Golgi; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0055038 recycling endosome membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005776 autophagosome; GO:0055037 recycling endosome; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0098791 Golgi subcompartment; GO:0044431 Golgi apparatus part; GO:0048471 perinuclear region of cytoplasm; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0010008 endosome membrane; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005802 trans-Golgi network; GO:0005773 vacuole; GO:0005794 Golgi apparatus; GO:0031984 organelle subcompartment; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0031267 small GTPase binding; GO:0031593 polyubiquitin binding; GO:0030674 protein binding, bridging; GO:0043167 ion binding; GO:0005515 protein binding; GO:0032182 ubiquitin-like protein binding; GO:0017137 Rab GTPase binding; GO:0042802 identical protein binding; GO:0017016 Ras GTPase binding; GO:0005488 binding; GO:0070530 K63-linked polyubiquitin binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0043130 ubiquitin binding; GO:0008022 protein C-terminus binding; GO:0060090 binding, bridging; GO:0051020 GTPase binding; GO:0019899 enzyme binding; ","K19946","OPTN; optineurin","hsa04137 Mitophagy - animal - Homo sapiens (human); ","IPR021063; IPR032419; ","\"NF-kappa-B essential modulator NEMO, N-terminal; NF-kappa-B essential modulator NEMO, CC2-LZ domain; \"\r"]
["Q96CW5","Gamma-tubulin complex component 3 OS=Homo sapiens OX=9606 GN=TUBGCP3","TUBGCP3",103.57,9.1945,4.1,3,3,3,0.961,1.114,1.109,0.909,0.964,0.956,0.889,0.0885,"nucleus\r","GO:0051418 microtubule nucleation by microtubule organizing center; GO:0044085 cellular component biogenesis; GO:0000003 reproduction; GO:0016043 cellular component organization; GO:0007098 centrosome cycle; GO:1903046 meiotic cell cycle process; GO:0031109 microtubule polymerization or depolymerization; GO:0022414 reproductive process; GO:0048285 organelle fission; GO:0007067 mitotic nuclear division; GO:0051297 centrosome organization; GO:0007051 spindle organization; GO:0044699 single-organism process; GO:1903047 mitotic cell cycle process; GO:0051225 spindle assembly; GO:0070925 organelle assembly; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0044702 single organism reproductive process; GO:0007052 mitotic spindle organization; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0043623 cellular protein complex assembly; GO:0000278 mitotic cell cycle; GO:0034622 cellular macromolecular complex assembly; GO:0051298 centrosome duplication; GO:0071822 protein complex subunit organization; GO:0044763 single-organism cellular process; GO:0019953 sexual reproduction; GO:0051321 meiotic cell cycle; GO:0007338 single fertilization; GO:0007017 microtubule-based process; GO:0051704 multi-organism process; GO:0031122 cytoplasmic microtubule organization; GO:0043933 macromolecular complex subunit organization; GO:0000226 microtubule cytoskeleton organization; GO:1902589 single-organism organelle organization; GO:0009566 fertilization; GO:0006996 organelle organization; GO:0031023 microtubule organizing center organization; GO:0007020 microtubule nucleation; GO:0044703 multi-organism reproductive process; GO:0051258 protein polymerization; GO:0000280 nuclear division; GO:0007126 meiotic nuclear division; GO:1902850 microtubule cytoskeleton organization involved in mitosis; GO:0090307 mitotic spindle assembly; GO:0022402 cell cycle process; GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center; GO:0046785 microtubule polymerization; GO:0070271 protein complex biogenesis; GO:0097435 supramolecular fiber organization; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044450 microtubule organizing center part; GO:0005874 microtubule; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0099512 supramolecular fiber; GO:0005623 cell; GO:0099080 supramolecular complex; GO:0032155 cell division site part; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0005815 microtubule organizing center; GO:0000923 equatorial microtubule organizing center; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0043229 intracellular organelle; GO:0005827 polar microtubule; GO:0000922 spindle pole; GO:0099513 polymeric cytoskeletal fiber; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0032153 cell division site; GO:0005829 cytosol; GO:0005819 spindle; GO:0099081 supramolecular polymer; GO:0005876 spindle microtubule; GO:0043226 organelle; GO:0005813 centrosome; GO:0008275 gamma-tubulin small complex; GO:0005814 centriole; GO:0000930 gamma-tubulin complex; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0008092 cytoskeletal protein binding; GO:0005200 structural constituent of cytoskeleton; GO:0005488 binding; GO:0015631 tubulin binding; GO:0043015 gamma-tubulin binding; GO:0005515 protein binding; GO:0005198 structural molecule activity; ","K16570"]
["Q96DC8","Enoyl-CoA hydratase domain-containing protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=ECHDC3","ECHDC3",32.633,25.256,19.5,5,6,5,0.992,1.078,1.01,0.949,0.887,0.958,0.907,0.0497,"mitochondria\r","GO:0008152 metabolic process; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044444 cytoplasmic part; ","GO:0003824 catalytic activity; ",{"$nulls":3},"IPR029045; ","ClpP/crotonase-like domain; \r"]
["Q96DX5","Ankyrin repeat and SOCS box protein 9 OS=Homo sapiens OX=9606 GN=ASB9","ASB9",31.857,6.56,6.5,1,1,1,1.145,0.929,0.861,1.06,0.958,1.058,1.048,0.592,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0060255 regulation of macromolecule metabolic process; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0009896 positive regulation of catabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0042176 regulation of protein catabolic process; GO:0009987 cellular process; GO:0051716 cellular response to stimulus; GO:0016567 protein ubiquitination; GO:0035556 intracellular signal transduction; GO:0080090 regulation of primary metabolic process; GO:0009894 regulation of catabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0023052 signaling; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0050789 regulation of biological process; GO:0051247 positive regulation of protein metabolic process; GO:0032446 protein modification by small protein conjugation; GO:0051246 regulation of protein metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0045732 positive regulation of protein catabolic process; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:0065007 biological regulation; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ","K10331",null,null,"IPR001496; IPR020683; ","SOCS box domain; Ankyrin repeat-containing domain; \r"]
["Q96EC8","Protein YIPF6 OS=Homo sapiens OX=9606 GN=YIPF6","YIPF6",26.256,2.5271,5.1,1,2,1,1.094,1.046,1.011,0.909,0.948,1.004,0.908,0.0579,"plasma membrane\r","GO:0032502 developmental process; GO:0060429 epithelium development; GO:0035295 tube development; GO:0044707 single-multicellular organism process; GO:0002064 epithelial cell development; GO:0009888 tissue development; GO:0048731 system development; GO:0048869 cellular developmental process; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0055123 digestive system development; GO:0002066 columnar/cuboidal epithelial cell development; GO:0032501 multicellular organismal process; GO:0048468 cell development; GO:0060576 intestinal epithelial cell development; GO:0030154 cell differentiation; GO:0002065 columnar/cuboidal epithelial cell differentiation; GO:0044767 single-organism developmental process; GO:0048565 digestive tract development; GO:0060575 intestinal epithelial cell differentiation; GO:0007275 multicellular organism development; GO:0048856 anatomical structure development; GO:0009987 cellular process; GO:0030855 epithelial cell differentiation; ","GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005801 cis-Golgi network; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0030134 ER to Golgi transport vesicle; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0030135 coated vesicle; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098791 Golgi subcompartment; GO:0005802 trans-Golgi network; GO:0044431 Golgi apparatus part; GO:0030133 transport vesicle; GO:0005794 Golgi apparatus; GO:0043227 membrane-bounded organelle; GO:0031984 organelle subcompartment; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0042802 identical protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR006977; ","Yip1 domain; \r"]
["Q96EE3","Nucleoporin SEH1 OS=Homo sapiens OX=9606 GN=SEH1L","SEH1L",39.648,13.81,14.7,4,5,4,0.985,0.932,0.982,1.031,0.909,1.163,1.07,0.437,"nucleus\r","GO:0050658 RNA transport; GO:0098542 defense response to other organism; GO:0051169 nuclear transport; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0009607 response to biotic stimulus; GO:1904263 positive regulation of TORC1 signaling; GO:1902583 multi-organism intracellular transport; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0002532 production of molecular mediator involved in inflammatory response; GO:0032879 regulation of localization; GO:0015931 nucleobase-containing compound transport; GO:0008608 attachment of spindle microtubules to kinetochore; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0075733 intracellular transport of virus; GO:0044419 interspecies interaction between organisms; GO:0008104 protein localization; GO:0044765 single-organism transport; GO:0051031 tRNA transport; GO:0007077 mitotic nuclear envelope disassembly; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0007059 chromosome segregation; GO:0044763 single-organism cellular process; GO:0032774 RNA biosynthetic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0006611 protein export from nucleus; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0051315 attachment of mitotic spindle microtubules to kinetochore; GO:0080135 regulation of cellular response to stress; GO:0031047 gene silencing by RNA; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0006913 nucleocytoplasmic transport; GO:0006464 cellular protein modification process; GO:0051301 cell division; GO:1901362 organic cyclic compound biosynthetic process; GO:0050794 regulation of cellular process; GO:0051640 organelle localization; GO:0046907 intracellular transport; GO:0044707 single-multicellular organism process; GO:0033554 cellular response to stress; GO:0016925 protein sumoylation; GO:0009267 cellular response to starvation; GO:0051028 mRNA transport; GO:0044267 cellular protein metabolic process; GO:0007080 mitotic metaphase plate congression; GO:0080134 regulation of response to stress; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0051236 establishment of RNA localization; GO:0046483 heterocycle metabolic process; GO:1902578 single-organism localization; GO:0034629 cellular protein complex localization; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0051081 nuclear envelope disassembly; GO:1903432 regulation of TORC1 signaling; GO:1902580 single-organism cellular localization; GO:0034613 cellular protein localization; GO:0009966 regulation of signal transduction; GO:0009617 response to bacterium; GO:1902531 regulation of intracellular signal transduction; GO:0046794 transport of virus; GO:0006950 response to stress; GO:0006403 RNA localization; GO:0006405 RNA export from nucleus; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0071496 cellular response to external stimulus; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0051656 establishment of organelle localization; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0031668 cellular response to extracellular stimulus; GO:0044766 multi-organism transport; GO:0045184 establishment of protein localization; GO:0006409 tRNA export from nucleus; GO:0051276 chromosome organization; GO:0032446 protein modification by small protein conjugation; GO:0001816 cytokine production; GO:0098813 nuclear chromosome segregation; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0000280 nuclear division; GO:0007062 sister chromatid cohesion; GO:0048584 positive regulation of response to stimulus; GO:0043412 macromolecule modification; GO:0051179 localization; GO:0010256 endomembrane system organization; GO:0007067 mitotic nuclear division; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:1902581 multi-organism cellular localization; GO:0051168 nuclear export; GO:0044764 multi-organism cellular process; GO:0071431 tRNA-containing ribonucleoprotein complex export from nucleus; GO:0051234 establishment of localization; GO:0000819 sister chromatid segregation; GO:0050000 chromosome localization; GO:0071427 mRNA-containing ribonucleoprotein complex export from nucleus; GO:0051649 establishment of localization in cell; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0050657 nucleic acid transport; GO:0002534 cytokine production involved in inflammatory response; GO:0033036 macromolecule localization; GO:0010827 regulation of glucose transport; GO:0010468 regulation of gene expression; GO:0071822 protein complex subunit organization; GO:0006999 nuclear pore organization; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0070647 protein modification by small protein conjugation or removal; GO:0010605 negative regulation of macromolecule metabolic process; GO:0050830 defense response to Gram-positive bacterium; GO:1902582 single-organism intracellular transport; GO:0071166 ribonucleoprotein complex localization; GO:0016070 RNA metabolic process; GO:1902589 single-organism organelle organization; GO:0030397 membrane disassembly; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006954 inflammatory response; GO:1900034 regulation of cellular response to heat; GO:0019222 regulation of metabolic process; GO:0006952 defense response; GO:0019083 viral transcription; GO:0036211 protein modification process; GO:0031503 protein complex localization; GO:0034198 cellular response to amino acid starvation; GO:0006997 nucleus organization; GO:0016043 cellular component organization; GO:1902579 multi-organism localization; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0048285 organelle fission; GO:0019058 viral life cycle; GO:0043207 response to external biotic stimulus; GO:0051310 metaphase plate congression; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0031669 cellular response to nutrient levels; GO:0006998 nuclear envelope organization; GO:0071704 organic substance metabolic process; GO:0018205 peptidyl-lysine modification; GO:0009991 response to extracellular stimulus; GO:0032006 regulation of TOR signaling; GO:0023056 positive regulation of signaling; GO:0016032 viral process; GO:0019080 viral gene expression; GO:0006886 intracellular protein transport; GO:0034641 cellular nitrogen compound metabolic process; GO:0010647 positive regulation of cell communication; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006406 mRNA export from nucleus; GO:0010629 negative regulation of gene expression; GO:0042742 defense response to bacterium; GO:0051303 establishment of chromosome localization; GO:0032008 positive regulation of TOR signaling; GO:0051049 regulation of transport; GO:0006807 nitrogen compound metabolic process; GO:0044802 single-organism membrane organization; GO:0000070 mitotic sister chromatid segregation; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0051641 cellular localization; GO:0018193 peptidyl-amino acid modification; GO:0016458 gene silencing; GO:0070727 cellular macromolecule localization; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0071426 ribonucleoprotein complex export from nucleus; GO:0022411 cellular component disassembly; GO:0010467 gene expression; GO:0042594 response to starvation; GO:0022402 cell cycle process; GO:0031667 response to nutrient levels; GO:0009967 positive regulation of signal transduction; GO:0007049 cell cycle; GO:0071705 nitrogen compound transport; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0000777 condensed chromosome kinetochore; GO:0043228 non-membrane-bounded organelle; GO:0044427 chromosomal part; GO:0000793 condensed chromosome; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0043227 membrane-bounded organelle; GO:0031080 nuclear pore outer ring; GO:0000776 kinetochore; GO:0043229 intracellular organelle; GO:0005643 nuclear pore; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005635 nuclear envelope; GO:0035859 Seh1-associated complex; GO:0000779 condensed chromosome, centromeric region; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0043226 organelle; GO:0098687 chromosomal region; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0061700 GATOR2 complex; GO:0031975 envelope; GO:0000775 chromosome, centromeric region; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0005488 binding; ","K14299","SEH1; nucleoporin SEH1","hsa03013 RNA transport - Homo sapiens (human); hsa04150 mTOR signaling pathway - Homo sapiens (human); ","IPR017986; IPR015943; ","WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain; \r"]
["Q96ER9","Coiled-coil domain-containing protein 51 OS=Homo sapiens OX=9606 GN=CCDC51","CCDC51",45.811,15.025,5.4,1,1,1,1.38,0.825,0.978,0.822,1.038,0.969,0.889,0.583,"mitochondria\r",null,"GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044464 cell part; GO:0005622 intracellular; GO:0044425 membrane part; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0016021 integral component of membrane; GO:0005739 mitochondrion; GO:0044444 cytoplasmic part; "]
["Q96EY5","Multivesicular body subunit 12A OS=Homo sapiens OX=9606 GN=MVB12A","MVB12A",28.783,2.3803,4.4,1,1,1,0.999,1.131,0.939,0.97,0.969,1.007,0.96,0.535,"nucleus\r","GO:0060627 regulation of vesicle-mediated transport; GO:0044085 cellular component biogenesis; GO:0010256 endomembrane system organization; GO:0023051 regulation of signaling; GO:0044764 multi-organism cellular process; GO:0006914 autophagy; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0010646 regulation of cell communication; GO:0019075 virus maturation; GO:0022607 cellular component assembly; GO:0032879 regulation of localization; GO:0036258 multivesicular body assembly; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0044419 interspecies interaction between organisms; GO:0016236 macroautophagy; GO:0043902 positive regulation of multi-organism process; GO:0039702 viral budding via host ESCRT complex; GO:0048522 positive regulation of cellular process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0036257 multivesicular body organization; GO:1903772 regulation of viral budding via host ESCRT complex; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0051704 multi-organism process; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0050789 regulation of biological process; GO:0030163 protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0019068 virion assembly; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0019058 viral life cycle; GO:0044267 cellular protein metabolic process; GO:1902592 multi-organism membrane budding; GO:0044087 regulation of cellular component biogenesis; GO:0071704 organic substance metabolic process; GO:0070925 organelle assembly; GO:1901184 regulation of ERBB signaling pathway; GO:0016032 viral process; GO:0044248 cellular catabolic process; GO:0006508 proteolysis; GO:0009987 cellular process; GO:0009966 regulation of signal transduction; GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; GO:0043632 modification-dependent macromolecule catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0019941 modification-dependent protein catabolic process; GO:0044803 multi-organism membrane organization; GO:0051049 regulation of transport; GO:0016192 vesicle-mediated transport; GO:0043900 regulation of multi-organism process; GO:0050792 regulation of viral process; GO:0016050 vesicle organization; GO:0033043 regulation of organelle organization; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:1902590 multi-organism organelle organization; GO:0048518 positive regulation of biological process; GO:0045184 establishment of protein localization; GO:0048524 positive regulation of viral process; GO:0046755 viral budding; GO:0006996 organelle organization; GO:0009057 macromolecule catabolic process; GO:0061024 membrane organization; GO:0006900 membrane budding; GO:0051128 regulation of cellular component organization; GO:0042058 regulation of epidermal growth factor receptor signaling pathway; GO:0051179 localization; GO:1903900 regulation of viral life cycle; GO:0009056 catabolic process; GO:0007032 endosome organization; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0036452 ESCRT complex; GO:0005815 microtubule organizing center; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0000813 ESCRT I complex; GO:0044425 membrane part; GO:0031902 late endosome membrane; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0010008 endosome membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0005770 late endosome; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0044440 endosomal part; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005813 centrosome; GO:0005794 Golgi apparatus; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005488 binding; GO:0008289 lipid binding; GO:0043130 ubiquitin binding; GO:0005515 protein binding; GO:0019904 protein domain specific binding; GO:0017124 SH3 domain binding; GO:0032182 ubiquitin-like protein binding; ","K12186","FAM125; ESCRT-I complex subunit MVB12","hsa04144 Endocytosis - Homo sapiens (human); ","IPR023340; IPR023341; ","UMA domain; MABP domain; \r"]
["Q96F10","Diamine acetyltransferase 2 OS=Homo sapiens OX=9606 GN=SAT2","SAT2",19.155,2.5338,9.4,2,2,2,1.115,0.989,1.092,0.919,0.938,0.961,0.882,0.0335,"cytoplasm\r","GO:0009447 putrescine catabolic process; GO:0044106 cellular amine metabolic process; GO:0032918 spermidine acetylation; GO:0008216 spermidine metabolic process; GO:0046204 nor-spermidine metabolic process; GO:0097164 ammonium ion metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0042402 cellular biogenic amine catabolic process; GO:0032920 putrescine acetylation; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0006576 cellular biogenic amine metabolic process; GO:0006595 polyamine metabolic process; GO:0006598 polyamine catabolic process; GO:1901575 organic substance catabolic process; GO:0008152 metabolic process; GO:1901565 organonitrogen compound catabolic process; GO:0009310 amine catabolic process; GO:0032917 polyamine acetylation; GO:0034641 cellular nitrogen compound metabolic process; GO:0008215 spermine metabolic process; GO:0009445 putrescine metabolic process; GO:0009056 catabolic process; GO:0009987 cellular process; GO:0032919 spermine acetylation; GO:0009308 amine metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:0016746 transferase activity, transferring acyl groups; GO:0042802 identical protein binding; GO:0004145 diamine N-acetyltransferase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0005515 protein binding; GO:0008080 N-acetyltransferase activity; GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups; GO:0016740 transferase activity; GO:0016407 acetyltransferase activity; GO:0016410 N-acyltransferase activity; ","K00657","speG; diamine N-acetyltransferase [EC:2.3.1.57]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa04216 Ferroptosis - Homo sapiens (human); hsa00330 Arginine and proline metabolism - Homo sapiens (human); ","IPR000182; IPR016181; ","GNAT domain; Acyl-CoA N-acyltransferase; \r"]
["Q96FJ2","Dynein light chain 2, cytoplasmic OS=Homo sapiens OX=9606 GN=DYNLL2","DYNLL2",10.35,44.661,57.3,4,8,2,1.027,1.027,1.026,0.945,1.05,0.903,0.941,0.294,"cytoplasm\r","GO:0098840 protein transport along microtubule; GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0010941 regulation of cell death; GO:0060271 cilium assembly; GO:0006914 autophagy; GO:0044237 cellular metabolic process; GO:0010821 regulation of mitochondrion organization; GO:0015031 protein transport; GO:0044782 cilium organization; GO:0008152 metabolic process; GO:1901028 regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; GO:0032879 regulation of localization; GO:1903747 regulation of establishment of protein localization to mitochondrion; GO:0090559 regulation of membrane permeability; GO:0008104 protein localization; GO:0044765 single-organism transport; GO:0007399 nervous system development; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; GO:0048583 regulation of response to stimulus; GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II; GO:0043068 positive regulation of programmed cell death; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0046907 intracellular transport; GO:0007006 mitochondrial membrane organization; GO:0043067 regulation of programmed cell death; GO:0008038 neuron recognition; GO:1905477 positive regulation of protein localization to membrane; GO:0030705 cytoskeleton-dependent intracellular transport; GO:0060341 regulation of cellular localization; GO:1900740 positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; GO:1902578 single-organism localization; GO:0044248 cellular catabolic process; GO:1901030 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; GO:1902580 single-organism cellular localization; GO:0007275 multicellular organism development; GO:0032880 regulation of protein localization; GO:0034613 cellular protein localization; GO:0009966 regulation of signal transduction; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0071702 organic substance transport; GO:0042073 intraciliary transport; GO:0007017 microtubule-based process; GO:0030031 cell projection assembly; GO:0045184 establishment of protein localization; GO:0030182 neuron differentiation; GO:1904951 positive regulation of establishment of protein localization; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0006928 movement of cell or subcellular component; GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:1903827 regulation of cellular protein localization; GO:0023051 regulation of signaling; GO:0006839 mitochondrial transport; GO:0048869 cellular developmental process; GO:0048666 neuron development; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:1903749 positive regulation of establishment of protein localization to mitochondrion; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:2001233 regulation of apoptotic signaling pathway; GO:0010970 transport along microtubule; GO:0051649 establishment of localization in cell; GO:0010646 regulation of cell communication; GO:0022607 cellular component assembly; GO:0007005 mitochondrion organization; GO:0033036 macromolecule localization; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0016236 macroautophagy; GO:0032502 developmental process; GO:0048002 antigen processing and presentation of peptide antigen; GO:0048522 positive regulation of cellular process; GO:0035735 intraciliary transport involved in cilium assembly; GO:0002495 antigen processing and presentation of peptide antigen via MHC class II; GO:1902582 single-organism intracellular transport; GO:0010942 positive regulation of cell death; GO:0051050 positive regulation of transport; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0030030 cell projection organization; GO:0010638 positive regulation of organelle organization; GO:0099118 microtubule-based protein transport; GO:0048856 anatomical structure development; GO:0031503 protein complex localization; GO:0016043 cellular component organization; GO:1903829 positive regulation of cellular protein localization; GO:0043065 positive regulation of apoptotic process; GO:0048193 Golgi vesicle transport; GO:0008037 cell recognition; GO:0070201 regulation of establishment of protein localization; GO:0099111 microtubule-based transport; GO:0048468 cell development; GO:1905475 regulation of protein localization to membrane; GO:0030154 cell differentiation; GO:0046902 regulation of mitochondrial membrane permeability; GO:0070925 organelle assembly; GO:0023056 positive regulation of signaling; GO:0008039 synaptic target recognition; GO:0006886 intracellular protein transport; GO:2001235 positive regulation of apoptotic signaling pathway; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:0051049 regulation of transport; GO:0033043 regulation of organelle organization; GO:0044802 single-organism membrane organization; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0010822 positive regulation of mitochondrion organization; GO:0007018 microtubule-based movement; GO:0019882 antigen processing and presentation; GO:0070727 cellular macromolecule localization; GO:0044767 single-organism developmental process; GO:0009967 positive regulation of signal transduction; GO:0051128 regulation of cellular component organization; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0009056 catabolic process; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005874 microtubule; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0099512 supramolecular fiber; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0005815 microtubule organizing center; GO:1902494 catalytic complex; GO:0044441 ciliary part; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0016459 myosin complex; GO:0043227 membrane-bounded organelle; GO:0005929 cilium; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0099513 polymeric cytoskeletal fiber; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0097542 ciliary tip; GO:0030286 dynein complex; GO:0005875 microtubule associated complex; GO:0005868 cytoplasmic dynein complex; GO:0044463 cell projection part; GO:0005829 cytosol; GO:0015629 actin cytoskeleton; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0099081 supramolecular polymer; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0005813 centrosome; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0008092 cytoskeletal protein binding; GO:0003774 motor activity; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017111 nucleoside-triphosphatase activity; ","K10418","DYNLL; dynein light chain LC8-type","hsa04962 Vasopressin-regulated water reabsorption - Homo sapiens (human); "]
["Q96FZ7","Charged multivesicular body protein 6 OS=Homo sapiens OX=9606 GN=CHMP6","CHMP6",23.485,5.1462,6.5,1,2,1,1.018,1.035,1.023,0.906,0.993,1.032,0.953,0.33,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0010256 endomembrane system organization; GO:0007067 mitotic nuclear division; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0006914 autophagy; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0050000 chromosome localization; GO:0000819 sister chromatid segregation; GO:0051649 establishment of localization in cell; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0036258 multivesicular body assembly; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0044419 interspecies interaction between organisms; GO:1904902 ESCRT III complex assembly; GO:0016236 macroautophagy; GO:0000278 mitotic cell cycle; GO:0007059 chromosome segregation; GO:0071822 protein complex subunit organization; GO:0039702 viral budding via host ESCRT complex; GO:0044763 single-organism cellular process; GO:0036257 multivesicular body organization; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:1904895 ESCRT complex assembly; GO:0051704 multi-organism process; GO:0016197 endosomal transport; GO:0006810 transport; GO:1902589 single-organism organelle organization; GO:0051301 cell division; GO:0070271 protein complex biogenesis; GO:0051640 organelle localization; GO:0016043 cellular component organization; GO:0006997 nucleus organization; GO:0019068 virion assembly; GO:0019058 viral life cycle; GO:0048285 organelle fission; GO:1902592 multi-organism membrane budding; GO:0000920 cell separation after cytokinesis; GO:0007080 mitotic metaphase plate congression; GO:0051310 metaphase plate congression; GO:1903047 mitotic cell cycle process; GO:0070925 organelle assembly; GO:0016032 viral process; GO:0044248 cellular catabolic process; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0044803 multi-organism membrane organization; GO:0051303 establishment of chromosome localization; GO:0016192 vesicle-mediated transport; GO:0016050 vesicle organization; GO:0000070 mitotic sister chromatid segregation; GO:0071702 organic substance transport; GO:0051656 establishment of organelle localization; GO:1902590 multi-organism organelle organization; GO:0043933 macromolecular complex subunit organization; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0051276 chromosome organization; GO:0046755 viral budding; GO:0006996 organelle organization; GO:0098813 nuclear chromosome segregation; GO:0007034 vacuolar transport; GO:0061024 membrane organization; GO:0006900 membrane budding; GO:0000280 nuclear division; GO:0022402 cell cycle process; GO:0051179 localization; GO:0009056 catabolic process; GO:0007032 endosome organization; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0036452 ESCRT complex; GO:0044425 membrane part; GO:0031902 late endosome membrane; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0000815 ESCRT III complex; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0010008 endosome membrane; GO:0098588 bounding membrane of organelle; GO:0005770 late endosome; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0047485 protein N-terminus binding; GO:0005488 binding; ","K12195","CHMP6; charged multivesicular body protein 6","hsa04144 Endocytosis - Homo sapiens (human); hsa04217 Necroptosis - Homo sapiens (human); "]
["Q96G03","Phosphoglucomutase-2 OS=Homo sapiens OX=9606 GN=PGM2","PGM2",68.283,86.265,28.9,18,27,18,0.989,0.973,0.992,1.029,0.981,1.043,1.034,0.17,"nucleus\r","GO:0046365 monosaccharide catabolic process; GO:0006739 NADP metabolic process; GO:0019362 pyridine nucleotide metabolic process; GO:0045321 leukocyte activation; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0072524 pyridine-containing compound metabolic process; GO:0044237 cellular metabolic process; GO:0044264 cellular polysaccharide metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0006006 glucose metabolic process; GO:0005980 glycogen catabolic process; GO:0008152 metabolic process; GO:0019692 deoxyribose phosphate metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0044262 cellular carbohydrate metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0006098 pentose-phosphate shunt; GO:0019693 ribose phosphate metabolic process; GO:0005978 glycogen biosynthetic process; GO:0043170 macromolecule metabolic process; GO:0034637 cellular carbohydrate biosynthetic process; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0002274 myeloid leukocyte activation; GO:0002443 leukocyte mediated immunity; GO:0009251 glucan catabolic process; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0006073 cellular glucan metabolic process; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0006081 cellular aldehyde metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0006732 coenzyme metabolic process; GO:0033692 cellular polysaccharide biosynthetic process; GO:0005975 carbohydrate metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0051186 cofactor metabolic process; GO:0016052 carbohydrate catabolic process; GO:0006810 transport; GO:0044723 single-organism carbohydrate metabolic process; GO:1901575 organic substance catabolic process; GO:0044710 single-organism metabolic process; GO:0032940 secretion by cell; GO:0015980 energy derivation by oxidation of organic compounds; GO:0044260 cellular macromolecule metabolic process; GO:0019388 galactose catabolic process; GO:0043299 leukocyte degranulation; GO:0016051 carbohydrate biosynthetic process; GO:0002283 neutrophil activation involved in immune response; GO:0006725 cellular aromatic compound metabolic process; GO:0046496 nicotinamide nucleotide metabolic process; GO:0000271 polysaccharide biosynthetic process; GO:0002252 immune effector process; GO:0046434 organophosphate catabolic process; GO:0044275 cellular carbohydrate catabolic process; GO:0044042 glucan metabolic process; GO:0006112 energy reserve metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0046386 deoxyribose phosphate catabolic process; GO:0051156 glucose 6-phosphate metabolic process; GO:0046483 heterocycle metabolic process; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0006139 nucleobase-containing compound metabolic process; GO:0019682 glyceraldehyde-3-phosphate metabolic process; GO:0005976 polysaccharide metabolic process; GO:0005996 monosaccharide metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0036230 granulocyte activation; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0044724 single-organism carbohydrate catabolic process; GO:0044711 single-organism biosynthetic process; GO:0044712 single-organism catabolic process; GO:0044247 cellular polysaccharide catabolic process; GO:0016192 vesicle-mediated transport; GO:0006807 nitrogen compound metabolic process; GO:0005977 glycogen metabolic process; GO:1901136 carbohydrate derivative catabolic process; GO:0044282 small molecule catabolic process; GO:0002376 immune system process; GO:0000272 polysaccharide catabolic process; GO:0043312 neutrophil degranulation; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0002263 cell activation involved in immune response; GO:0044249 cellular biosynthetic process; GO:0009250 glucan biosynthetic process; GO:0002366 leukocyte activation involved in immune response; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:0034645 cellular macromolecule biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0009057 macromolecule catabolic process; GO:0001775 cell activation; GO:0019637 organophosphate metabolic process; GO:0019320 hexose catabolic process; GO:0051179 localization; GO:0006955 immune response; GO:0006012 galactose metabolic process; GO:0009056 catabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0006887 exocytosis; GO:0019318 hexose metabolic process; ","GO:0034774 secretory granule lumen; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044433 cytoplasmic vesicle part; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0060205 cytoplasmic vesicle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0000287 magnesium ion binding; GO:0016853 isomerase activity; GO:0003824 catalytic activity; GO:0004614 phosphoglucomutase activity; GO:0005488 binding; GO:0016868 intramolecular transferase activity, phosphotransferases; GO:0043167 ion binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0008973 phosphopentomutase activity; GO:0005515 protein binding; GO:0016866 intramolecular transferase activity; ","K15779","PGM2; phosphoglucomutase / phosphopentomutase [EC:5.4.2.2 5.4.2.7]","hsa00230 Purine metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00500 Starch and sucrose metabolism - Homo sapiens (human); hsa00030 Pentose phosphate pathway - Homo sapiens (human); hsa00052 Galactose metabolism - Homo sapiens (human); hsa00520 Amino sugar and nucleotide sugar metabolism - Homo sapiens (human); hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human); ","IPR005846; IPR005843; IPR005845; IPR016055; IPR005844; ","\"Alpha-D-phosphohexomutase, alpha/beta/alpha domain III; Alpha-D-phosphohexomutase, C-terminal; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III; Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; \"\r"]
["Q96GK7","Fumarylacetoacetate hydrolase domain-containing protein 2A OS=Homo sapiens OX=9606 GN=FAHD2A","FAHD2A",34.596,21.684,16.9,5,6,5,1.035,0.879,1.117,0.992,1.066,0.916,0.981,0.857,"mitochondria\r","GO:0008152 metabolic process; ",null,"GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0016787 hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; ",{"$nulls":3},"IPR011234; ","\"Fumarylacetoacetase, C-terminal-related; \"\r"]
["Q96GQ5","RUS1 family protein C16orf58 OS=Homo sapiens OX=9606 GN=C16orf58","C16orf58",51.017,21.302,10.3,3,3,3,1.087,0.945,1.086,0.974,0.936,0.972,0.924,0.187,"cytoplasm\r",null,"GO:0031224 intrinsic component of membrane; GO:0016020 membrane; GO:0016021 integral component of membrane; GO:0044425 membrane part; "]
["Q96HC4","PDZ and LIM domain protein 5 OS=Homo sapiens OX=9606 GN=PDLIM5","PDLIM5",63.944,38.295,14.8,8,10,8,0.838,1.083,1.087,0.994,0.971,1.034,0.997,0.967,"nucleus\r","GO:0003012 muscle system process; GO:0065008 regulation of biological quality; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0050807 regulation of synapse organization; GO:0022610 biological adhesion; GO:0007507 heart development; GO:0003298 physiological muscle hypertrophy; GO:0007155 cell adhesion; GO:0055017 cardiac muscle tissue growth; GO:0055013 cardiac muscle cell development; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0009888 tissue development; GO:0060998 regulation of dendritic spine development; GO:0060537 muscle tissue development; GO:0016049 cell growth; GO:0048699 generation of neurons; GO:0051963 regulation of synapse assembly; GO:0098609 cell-cell adhesion; GO:0044763 single-organism cellular process; GO:0032501 multicellular organismal process; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0014896 muscle hypertrophy; GO:0055002 striated muscle cell development; GO:0045664 regulation of neuron differentiation; GO:0048856 anatomical structure development; GO:0014897 striated muscle hypertrophy; GO:0010975 regulation of neuron projection development; GO:0060419 heart growth; GO:2000026 regulation of multicellular organismal development; GO:0050794 regulation of cellular process; GO:0055001 muscle cell development; GO:0072359 circulatory system development; GO:0014706 striated muscle tissue development; GO:0044707 single-multicellular organism process; GO:0055006 cardiac cell development; GO:0061001 regulation of dendritic spine morphogenesis; GO:0048738 cardiac muscle tissue development; GO:0031344 regulation of cell projection organization; GO:0044087 regulation of cellular component biogenesis; GO:0048814 regulation of dendrite morphogenesis; GO:0051239 regulation of multicellular organismal process; GO:0048468 cell development; GO:0035265 organ growth; GO:0055007 cardiac muscle cell differentiation; GO:0030154 cell differentiation; GO:0003300 cardiac muscle hypertrophy; GO:0061061 muscle structure development; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0051146 striated muscle cell differentiation; GO:0050803 regulation of synapse structure or activity; GO:0035051 cardiocyte differentiation; GO:0003008 system process; GO:0048731 system development; GO:0051960 regulation of nervous system development; GO:0060284 regulation of cell development; GO:0048588 developmental cell growth; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0061049 cell growth involved in cardiac muscle cell development; GO:0042692 muscle cell differentiation; GO:0050773 regulation of dendrite development; GO:0003301 physiological cardiac muscle hypertrophy; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:0051128 regulation of cellular component organization; GO:0048589 developmental growth; GO:0040007 growth; GO:0022604 regulation of cell morphogenesis; GO:0050793 regulation of developmental process; GO:0065007 biological regulation; GO:0050767 regulation of neurogenesis; ","GO:0016020 membrane; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005913 cell-cell adherens junction; GO:0005623 cell; GO:0005911 cell-cell junction; GO:0032279 asymmetric synapse; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0098590 plasma membrane region; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0014069 postsynaptic density; GO:0005912 adherens junction; GO:0043005 neuron projection; GO:0097060 synaptic membrane; GO:0097458 neuron part; GO:0098984 neuron to neuron synapse; GO:0044456 synapse part; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0070161 anchoring junction; GO:0005829 cytosol; GO:0015629 actin cytoskeleton; GO:0045202 synapse; GO:0005886 plasma membrane; GO:0045211 postsynaptic membrane; GO:0043226 organelle; GO:0098794 postsynapse; GO:0044459 plasma membrane part; GO:0099572 postsynaptic specialization; GO:0044444 cytoplasmic part; ","GO:0047485 protein N-terminus binding; GO:0019901 protein kinase binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0019900 kinase binding; GO:0098632 protein binding involved in cell-cell adhesion; GO:0008270 zinc ion binding; GO:0050839 cell adhesion molecule binding; GO:0098641 cadherin binding involved in cell-cell adhesion; GO:0008092 cytoskeletal protein binding; GO:0046914 transition metal ion binding; GO:0098631 protein binding involved in cell adhesion; GO:0005488 binding; GO:0045296 cadherin binding; GO:0042805 actinin binding; GO:0003779 actin binding; GO:0005080 protein kinase C binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0019899 enzyme binding; ",{"$nulls":3},"IPR001781; IPR001478; IPR031847; ","\"Zinc finger, LIM-type; PDZ domain; Domain of unknown function DUF4749; \"\r"]
["Q96HE7","ERO1-like protein alpha OS=Homo sapiens OX=9606 GN=ERO1A","ERO1A",54.392,58.243,28.2,11,16,11,0.941,0.933,0.891,1.059,1.112,1.07,1.172,2.14E-3,"extracellular\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0006458 'de novo' protein folding; GO:0035966 response to topologically incorrect protein; GO:0032879 regulation of localization; GO:0060402 calcium ion transport into cytosol; GO:0055065 metal ion homeostasis; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044765 single-organism transport; GO:0051716 cellular response to stimulus; GO:0044281 small molecule metabolic process; GO:0000302 response to reactive oxygen species; GO:0044763 single-organism cellular process; GO:0032501 multicellular organismal process; GO:0006874 cellular calcium ion homeostasis; GO:0006810 transport; GO:0048513 animal organ development; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0098662 inorganic cation transmembrane transport; GO:0043436 oxoacid metabolic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0044707 single-multicellular organism process; GO:0034220 ion transmembrane transport; GO:0097190 apoptotic signaling pathway; GO:0034976 response to endoplasmic reticulum stress; GO:0030001 metal ion transport; GO:0009628 response to abiotic stimulus; GO:0045454 cell redox homeostasis; GO:0044267 cellular protein metabolic process; GO:1901700 response to oxygen-containing compound; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0032844 regulation of homeostatic process; GO:1902578 single-organism localization; GO:0043062 extracellular structure organization; GO:0070482 response to oxygen levels; GO:0007275 multicellular organism development; GO:0051209 release of sequestered calcium ion into cytosol; GO:0048878 chemical homeostasis; GO:0070588 calcium ion transmembrane transport; GO:0071456 cellular response to hypoxia; GO:0006986 response to unfolded protein; GO:0051282 regulation of sequestering of calcium ion; GO:0051084 'de novo' posttranslational protein folding; GO:0006950 response to stress; GO:0048731 system development; GO:1902656 calcium ion import into cytosol; GO:0010033 response to organic substance; GO:1901605 alpha-amino acid metabolic process; GO:0044238 primary metabolic process; GO:0055085 transmembrane transport; GO:0006873 cellular ion homeostasis; GO:0006811 ion transport; GO:0036293 response to decreased oxygen levels; GO:0012501 programmed cell death; GO:0051179 localization; GO:0007204 positive regulation of cytosolic calcium ion concentration; GO:0043412 macromolecule modification; GO:0070838 divalent metal ion transport; GO:1901564 organonitrogen compound metabolic process; GO:0072503 cellular divalent inorganic cation homeostasis; GO:0061077 chaperone-mediated protein folding; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0030968 endoplasmic reticulum unfolded protein response; GO:0051234 establishment of localization; GO:0006457 protein folding; GO:0007165 signal transduction; GO:0006520 cellular amino acid metabolic process; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0006915 apoptotic process; GO:0006979 response to oxidative stress; GO:0019471 4-hydroxyproline metabolic process; GO:0030198 extracellular matrix organization; GO:0050873 brown fat cell differentiation; GO:0060401 cytosolic calcium ion transport; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0097553 calcium ion transmembrane import into cytosol; GO:0098655 cation transmembrane transport; GO:0050801 ion homeostasis; GO:0055114 oxidation-reduction process; GO:0055074 calcium ion homeostasis; GO:0098771 inorganic ion homeostasis; GO:0019725 cellular homeostasis; GO:0023052 signaling; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0007568 aging; GO:0070509 calcium ion import; GO:0045444 fat cell differentiation; GO:0006082 organic acid metabolic process; GO:0036211 protein modification process; GO:0072507 divalent inorganic cation homeostasis; GO:0048856 anatomical structure development; GO:0016043 cellular component organization; GO:0072511 divalent inorganic cation transport; GO:0035967 cellular response to topologically incorrect protein; GO:2000021 regulation of ion homeostasis; GO:0071310 cellular response to organic substance; GO:0051480 regulation of cytosolic calcium ion concentration; GO:0030003 cellular cation homeostasis; GO:0034975 protein folding in endoplasmic reticulum; GO:0050896 response to stimulus; GO:0097193 intrinsic apoptotic signaling pathway; GO:0055082 cellular chemical homeostasis; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0010260 animal organ senescence; GO:0030154 cell differentiation; GO:0006575 cellular modified amino acid metabolic process; GO:0055080 cation homeostasis; GO:0006816 calcium ion transport; GO:0006812 cation transport; GO:0001666 response to hypoxia; GO:0009266 response to temperature stimulus; GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; GO:0071453 cellular response to oxygen levels; GO:0009987 cellular process; GO:0051085 chaperone mediated protein folding requiring cofactor; GO:0034620 cellular response to unfolded protein; GO:0022417 protein maturation by protein folding; GO:0035556 intracellular signal transduction; GO:0098660 inorganic ion transmembrane transport; GO:0006807 nitrogen compound metabolic process; GO:0032845 negative regulation of homeostatic process; GO:0051283 negative regulation of sequestering of calcium ion; GO:0051641 cellular localization; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0019752 carboxylic acid metabolic process; GO:0006875 cellular metal ion homeostasis; GO:0010467 gene expression; GO:0051604 protein maturation; GO:0036294 cellular response to decreased oxygen levels; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0005788 endoplasmic reticulum lumen; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0030425 dendrite; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0042995 cell projection; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0070013 intracellular organelle lumen; GO:0044432 endoplasmic reticulum part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0015035 protein disulfide oxidoreductase activity; GO:0015036 disulfide oxidoreductase activity; GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds; GO:0016853 isomerase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016667 oxidoreductase activity, acting on a sulfur group of donors; GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor; GO:0005515 protein binding; GO:0016860 intramolecular oxidoreductase activity; GO:0003756 protein disulfide isomerase activity; GO:0016491 oxidoreductase activity; ","K10950","ERO1L; ERO1-like protein alpha [EC:1.8.4.-]","hsa05110 Vibrio cholerae infection - Homo sapiens (human); hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); "]
["Q96HP4","Oxidoreductase NAD-binding domain-containing protein 1 OS=Homo sapiens OX=9606 GN=OXNAD1","OXNAD1",34.854,1.9075,2.2,1,1,1,0.98,1.061,0.971,1.019,1.008,0.972,0.996,0.912,"extracellular\r","GO:0044699 single-organism process; GO:0008152 metabolic process; GO:0055114 oxidation-reduction process; GO:0044710 single-organism metabolic process; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044444 cytoplasmic part; ","GO:0003824 catalytic activity; GO:0016491 oxidoreductase activity; ",{"$nulls":3},"IPR001433; IPR017927; IPR017938; ","Oxidoreductase FAD/NAD(P)-binding; Ferredoxin reductase-type FAD-binding domain; Riboflavin synthase-like beta-barrel; \r"]
["Q96HV5","Transmembrane protein 41A OS=Homo sapiens OX=9606 GN=TMEM41A","TMEM41A",29.665,6.9592,4.5,1,1,1,0.915,1.108,0.848,1.05,1.051,1.036,1.093,0.355,"plasma membrane\r",null,"GO:0031224 intrinsic component of membrane; GO:0016020 membrane; GO:0016021 integral component of membrane; GO:0044425 membrane part; ","GO:0005515 protein binding; GO:0005488 binding; "]
["Q96I15","Selenocysteine lyase OS=Homo sapiens OX=9606 GN=SCLY","SCLY",48.148,3.2468,3.8,1,1,1,0.963,1.005,0.948,0.928,1.076,1.081,1.058,0.365,"cytoplasm\r","GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:0044699 single-organism process; GO:0044238 primary metabolic process; GO:0001887 selenium compound metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0044710 single-organism metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0006082 organic acid metabolic process; GO:0009987 cellular process; GO:0043436 oxoacid metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0044444 cytoplasmic part; ","GO:0003824 catalytic activity; GO:0005488 binding; GO:0016829 lyase activity; GO:0009000 selenocysteine lyase activity; GO:0005515 protein binding; GO:0016846 carbon-sulfur lyase activity; GO:0016740 transferase activity; ","K01763","SCLY; selenocysteine lyase [EC:4.4.1.16]","hsa00450 Selenocompound metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR015424; IPR000192; IPR015422; IPR015421; ","\"Pyridoxal phosphate-dependent transferase; Aminotransferase class V domain; Pyridoxal phosphate-dependent transferase, major region, subdomain 2; Pyridoxal phosphate-dependent transferase, major region, subdomain 1; \"\r"]
["Q96I24","Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3","FUBP3",61.64,26.856,17.3,7,8,6,1.092,0.95,0.759,1.21,0.919,1.082,1.146,0.347,"cytoskeleton\r","GO:0097659 nucleic acid-templated transcription; GO:0009891 positive regulation of biosynthetic process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0043170 macromolecule metabolic process; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0051254 positive regulation of RNA metabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0031325 positive regulation of cellular metabolic process; GO:0006366 transcription from RNA polymerase II promoter; GO:0010467 gene expression; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0065007 biological regulation; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; ","GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding; GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding; GO:0003677 DNA binding; GO:0003723 RNA binding; GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding; GO:0000976 transcription regulatory region sequence-specific DNA binding; GO:0003690 double-stranded DNA binding; GO:1990837 sequence-specific double-stranded DNA binding; GO:0001012 RNA polymerase II regulatory region DNA binding; GO:0005515 protein binding; GO:0043565 sequence-specific DNA binding; GO:0000987 core promoter proximal region sequence-specific DNA binding; GO:0003700 transcription factor activity, sequence-specific DNA binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0001159 core promoter proximal region DNA binding; GO:0000975 regulatory region DNA binding; GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding; GO:0001067 regulatory region nucleic acid binding; GO:0044212 transcription regulatory region DNA binding; GO:0005488 binding; GO:0001071 nucleic acid binding transcription factor activity; GO:0003676 nucleic acid binding; GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding; GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding; ","K13210",null,null,"IPR004087; IPR004088; ","\"K Homology domain; K Homology domain, type 1; \"\r"]
["Q96IJ6","Mannose-1-phosphate guanyltransferase alpha OS=Homo sapiens OX=9606 GN=GMPPA","GMPPA",46.291,9.945,13.6,6,8,6,0.96,1.028,1.001,1.04,0.978,1.024,1.018,0.552,"mitochondria\r","GO:0009058 biosynthetic process; GO:0008152 metabolic process; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:0005515 protein binding; GO:0016779 nucleotidyltransferase activity; GO:0003824 catalytic activity; GO:0016740 transferase activity; GO:0005488 binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K00966","GMPP; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]","hsa00051 Fructose and mannose metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00520 Amino sugar and nucleotide sugar metabolism - Homo sapiens (human); ","IPR005835; IPR029044; ","Nucleotidyl transferase domain; Nucleotide-diphospho-sugar transferases; \r"]
["Q96IZ0","PRKC apoptosis WT1 regulator protein OS=Homo sapiens OX=9606 GN=PAWR","PAWR",36.567,9.0784,10,3,4,3,0.891,0.854,1.072,1.096,1.107,0.977,1.129,0.197,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0002694 regulation of leukocyte activation; GO:0050672 negative regulation of lymphocyte proliferation; GO:0010941 regulation of cell death; GO:0032944 regulation of mononuclear cell proliferation; GO:0090342 regulation of cell aging; GO:0097659 nucleic acid-templated transcription; GO:0009891 positive regulation of biosynthetic process; GO:0044237 cellular metabolic process; GO:0008285 negative regulation of cell proliferation; GO:0030888 regulation of B cell proliferation; GO:0048145 regulation of fibroblast proliferation; GO:1901298 regulation of hydrogen peroxide-mediated programmed cell death; GO:0030036 actin cytoskeleton organization; GO:0008152 metabolic process; GO:0070664 negative regulation of leukocyte proliferation; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:2000772 regulation of cellular senescence; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0050864 regulation of B cell activation; GO:1903038 negative regulation of leukocyte cell-cell adhesion; GO:0010559 regulation of glycoprotein biosynthetic process; GO:0000122 negative regulation of transcription from RNA polymerase II promoter; GO:0044763 single-organism cellular process; GO:0032774 RNA biosynthetic process; GO:0050670 regulation of lymphocyte proliferation; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0050776 regulation of immune response; GO:1903506 regulation of nucleic acid-templated transcription; GO:0080135 regulation of cellular response to stress; GO:1903205 regulation of hydrogen peroxide-induced cell death; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:2000774 positive regulation of cellular senescence; GO:0010604 positive regulation of macromolecule metabolic process; GO:0002682 regulation of immune system process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0051094 positive regulation of developmental process; GO:0097435 supramolecular fiber organization; GO:1901362 organic cyclic compound biosynthetic process; GO:0043068 positive regulation of programmed cell death; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0007162 negative regulation of cell adhesion; GO:1905206 positive regulation of hydrogen peroxide-induced cell death; GO:0097190 apoptotic signaling pathway; GO:0042127 regulation of cell proliferation; GO:0050860 negative regulation of T cell receptor signaling pathway; GO:0043067 regulation of programmed cell death; GO:0022408 negative regulation of cell-cell adhesion; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0080134 regulation of response to stress; GO:0050866 negative regulation of cell activation; GO:0045892 negative regulation of transcription, DNA-templated; GO:1902884 positive regulation of response to oxidative stress; GO:0023057 negative regulation of signaling; GO:0046483 heterocycle metabolic process; GO:0010648 negative regulation of cell communication; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:0051171 regulation of nitrogen compound metabolic process; GO:0007010 cytoskeleton organization; GO:0042089 cytokine biosynthetic process; GO:0090343 positive regulation of cell aging; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0009966 regulation of signal transduction; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1903018 regulation of glycoprotein metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0030155 regulation of cell adhesion; GO:0032623 interleukin-2 production; GO:0061572 actin filament bundle organization; GO:0009890 negative regulation of biosynthetic process; GO:0051247 positive regulation of protein metabolic process; GO:0006996 organelle organization; GO:0001816 cytokine production; GO:0030029 actin filament-based process; GO:0031325 positive regulation of cellular metabolic process; GO:1902882 regulation of response to oxidative stress; GO:0012501 programmed cell death; GO:0048584 positive regulation of response to stimulus; GO:0031328 positive regulation of cellular biosynthetic process; GO:0050793 regulation of developmental process; GO:1903209 positive regulation of oxidative stress-induced cell death; GO:0050863 regulation of T cell activation; GO:1901300 positive regulation of hydrogen peroxide-mediated programmed cell death; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:1901033 positive regulation of response to reactive oxygen species; GO:1900409 positive regulation of cellular response to oxidative stress; GO:0044699 single-organism process; GO:0042130 negative regulation of T cell proliferation; GO:0009058 biosynthetic process; GO:0051249 regulation of lymphocyte activation; GO:0050858 negative regulation of antigen receptor-mediated signaling pathway; GO:0051253 negative regulation of RNA metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:1903020 positive regulation of glycoprotein metabolic process; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0009893 positive regulation of metabolic process; GO:0048147 negative regulation of fibroblast proliferation; GO:0006915 apoptotic process; GO:0042107 cytokine metabolic process; GO:0070663 regulation of leukocyte proliferation; GO:0030889 negative regulation of B cell proliferation; GO:0002695 negative regulation of leukocyte activation; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0042986 positive regulation of amyloid precursor protein biosynthetic process; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0010942 positive regulation of cell death; GO:0016070 RNA metabolic process; GO:0002683 negative regulation of immune system process; GO:1902589 single-organism organelle organization; GO:0050865 regulation of cell activation; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:1902679 negative regulation of RNA biosynthetic process; GO:0050856 regulation of T cell receptor signaling pathway; GO:0019222 regulation of metabolic process; GO:0050868 negative regulation of T cell activation; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0051250 negative regulation of lymphocyte activation; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0007015 actin filament organization; GO:0043065 positive regulation of apoptotic process; GO:1903201 regulation of oxidative stress-induced cell death; GO:0051017 actin filament bundle assembly; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0050854 regulation of antigen receptor-mediated signaling pathway; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0010560 positive regulation of glycoprotein biosynthetic process; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0050869 negative regulation of B cell activation; GO:0042094 interleukin-2 biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0042129 regulation of T cell proliferation; GO:0010556 regulation of macromolecule biosynthetic process; GO:0042984 regulation of amyloid precursor protein biosynthetic process; GO:0032945 negative regulation of mononuclear cell proliferation; GO:0048585 negative regulation of response to stimulus; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0022407 regulation of cell-cell adhesion; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:1900407 regulation of cellular response to oxidative stress; GO:0008219 cell death; GO:0051246 regulation of protein metabolic process; GO:0010467 gene expression; GO:0031327 negative regulation of cellular biosynthetic process; GO:1901031 regulation of response to reactive oxygen species; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0000785 chromatin; GO:0044454 nuclear chromosome part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0000790 nuclear chromatin; GO:0000228 nuclear chromosome; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0003714 transcription corepressor activity; GO:0008092 cytoskeletal protein binding; GO:0030275 LRR domain binding; GO:0005488 binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0003779 actin binding; GO:0019904 protein domain specific binding; GO:0005515 protein binding; GO:0003712 transcription cofactor activity; GO:0000988 transcription factor activity, protein binding; GO:0019899 enzyme binding; GO:0043522 leucine zipper domain binding; "]
["Q96JC1","Vam6/Vps39-like protein OS=Homo sapiens OX=9606 GN=VPS39","VPS39",101.81,5.099,2.6,2,2,2,0.907,1.044,1.011,1.032,0.857,1.155,1.028,0.834,"cytoplasm\r","GO:0090174 organelle membrane fusion; GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0044699 single-organism process; GO:0006914 autophagy; GO:1902774 late endosome to lysosome transport; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0045324 late endosome to vacuole transport; GO:0006886 intracellular protein transport; GO:0044248 cellular catabolic process; GO:1990126 retrograde transport, endosome to plasma membrane; GO:0007033 vacuole organization; GO:0044801 single-organism membrane fusion; GO:0034613 cellular protein localization; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0034058 endosomal vesicle fusion; GO:0009987 cellular process; GO:0007041 lysosomal transport; GO:0098876 vesicle-mediated transport to the plasma membrane; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0044802 single-organism membrane organization; GO:0016050 vesicle organization; GO:0061025 membrane fusion; GO:0071702 organic substance transport; GO:0048284 organelle fusion; GO:0008333 endosome to lysosome transport; GO:0051641 cellular localization; GO:0016197 endosomal transport; GO:0006810 transport; GO:0045184 establishment of protein localization; GO:1902589 single-organism organelle organization; GO:0070727 cellular macromolecule localization; GO:0097576 vacuole fusion; GO:0007034 vacuolar transport; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0006906 vesicle fusion; GO:0051179 localization; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0030119 AP-type membrane coat adaptor complex; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0030123 AP-3 adaptor complex; GO:0005765 lysosomal membrane; GO:0031902 late endosome membrane; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0098805 whole membrane; GO:0005764 lysosome; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0099023 tethering complex; GO:0000323 lytic vacuole; GO:0010008 endosome membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0005770 late endosome; GO:0098588 bounding membrane of organelle; GO:0048475 coated membrane; GO:0044446 intracellular organelle part; GO:0044440 endosomal part; GO:0012505 endomembrane system; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0030117 membrane coat; GO:0030897 HOPS complex; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ",null,"K20183",null,null,"IPR001180; IPR019452; IPR019453; ","Citron homology (CNH) domain; Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 1; Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 2; \r"]
["Q96JH7","Deubiquitinating protein VCIP135 OS=Homo sapiens OX=9606 GN=VCPIP1","VCPIP1",134.32,2.0864,0.7,1,1,1,1.073,0.93,1.055,0.923,0.894,1.13,0.964,0.663,"cyto_nucl\r","GO:0044085 cellular component biogenesis; GO:0090174 organelle membrane fusion; GO:0016043 cellular component organization; GO:0070646 protein modification by small protein removal; GO:0010256 endomembrane system organization; GO:0048313 Golgi inheritance; GO:0007067 mitotic nuclear division; GO:0048285 organelle fission; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0016579 protein deubiquitination; GO:1903047 mitotic cell cycle process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0022607 cellular component assembly; GO:0048308 organelle inheritance; GO:0006508 proteolysis; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044801 single-organism membrane fusion; GO:0009987 cellular process; GO:0071108 protein K48-linked deubiquitination; GO:0000278 mitotic cell cycle; GO:0016567 protein ubiquitination; GO:0090168 Golgi reassembly; GO:0044763 single-organism cellular process; GO:0044802 single-organism membrane organization; GO:0061025 membrane fusion; GO:0048284 organelle fusion; GO:0070647 protein modification by small protein conjugation or removal; GO:0044238 primary metabolic process; GO:1902589 single-organism organelle organization; GO:0016320 endoplasmic reticulum membrane fusion; GO:0032446 protein modification by small protein conjugation; GO:0007030 Golgi organization; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0044260 cellular macromolecule metabolic process; GO:0000280 nuclear division; GO:0006464 cellular protein modification process; GO:0022402 cell cycle process; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:0007049 cell cycle; GO:0035871 protein K11-linked deubiquitination; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0005783 endoplasmic reticulum; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0005795 Golgi stack; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005622 intracellular; GO:0044464 cell part; GO:0098791 Golgi subcompartment; GO:0044431 Golgi apparatus part; GO:0005794 Golgi apparatus; GO:0043227 membrane-bounded organelle; GO:0031984 organelle subcompartment; GO:0044444 cytoplasmic part; ","GO:0004843 thiol-dependent ubiquitin-specific protease activity; GO:0008233 peptidase activity; GO:0036459 thiol-dependent ubiquitinyl hydrolase activity; GO:0003824 catalytic activity; GO:0101005 ubiquitinyl hydrolase activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0019783 ubiquitin-like protein-specific protease activity; GO:0008234 cysteine-type peptidase activity; GO:0016787 hydrolase activity; ","K11861",null,null,"IPR003323; IPR029071; ","OTU domain; Ubiquitin-related domain; \r"]
["Q96K17","Transcription factor BTF3 homolog 4 OS=Homo sapiens OX=9606 GN=BTF3L4","BTF3L4",17.27,32.204,27.8,5,6,4,0.989,1.012,1.033,0.96,1.009,1.005,0.98,0.379,"mitochondria\r",null,null,"GO:0005515 protein binding; GO:0005488 binding; ","K01527",null,null,"IPR002715; ","Nascent polypeptide-associated complex NAC domain; \r"]
["Q96KP1","Exocyst complex component 2 OS=Homo sapiens OX=9606 GN=EXOC2","EXOC2",104.07,74.022,10.8,9,10,9,0.978,1.018,1.025,1.017,0.962,1.019,0.992,0.761,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:2000535 regulation of entry of bacterium into host cell; GO:0016043 cellular component organization; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0048193 Golgi vesicle transport; GO:0044699 single-organism process; GO:0022406 membrane docking; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:1902578 single-organism localization; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0006893 Golgi to plasma membrane transport; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0043623 cellular protein complex assembly; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0034622 cellular macromolecular complex assembly; GO:0071822 protein complex subunit organization; GO:0098876 vesicle-mediated transport to the plasma membrane; GO:0006904 vesicle docking involved in exocytosis; GO:0043900 regulation of multi-organism process; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0071702 organic substance transport; GO:0048278 vesicle docking; GO:0043933 macromolecular complex subunit organization; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0001927 exocyst assembly; GO:0032940 secretion by cell; GO:0006892 post-Golgi vesicle-mediated transport; GO:0051179 localization; GO:0070271 protein complex biogenesis; GO:0065007 biological regulation; GO:0006887 exocytosis; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0005938 cell cortex; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0099568 cytoplasmic region; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0000145 exocyst; GO:0005829 cytosol; GO:0005623 cell; GO:0005886 plasma membrane; GO:0005622 intracellular; GO:0044448 cell cortex part; GO:0044464 cell part; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0099023 tethering complex; ","GO:0031267 small GTPase binding; GO:0047485 protein N-terminus binding; GO:0017016 Ras GTPase binding; GO:0005488 binding; GO:0019901 protein kinase binding; GO:0005515 protein binding; GO:0051020 GTPase binding; GO:0019900 kinase binding; GO:0017160 Ral GTPase binding; GO:0019899 enzyme binding; ","K17637","EXOC2; exocyst complex component 2","hsa04014 Ras signaling pathway - Homo sapiens (human); ","IPR013783; IPR014756; IPR002909; ","Immunoglobulin-like fold; Immunoglobulin E-set; IPT domain; \r"]
["Q96KS0","Egl nine homolog 2 OS=Homo sapiens OX=9606 GN=EGLN2","EGLN2",43.65,2.1061,2.2,1,2,1,0.82,0.795,0.77,1.153,1.24,1.203,1.508,1.22E-4,"nucleus\r","GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0065008 regulation of biological quality; GO:0043523 regulation of neuron apoptotic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0071383 cellular response to steroid hormone stimulus; GO:0030520 intracellular estrogen receptor signaling pathway; GO:0001558 regulation of cell growth; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0030522 intracellular receptor signaling pathway; GO:0048545 response to steroid hormone; GO:0009719 response to endogenous stimulus; GO:0019471 4-hydroxyproline metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0030518 intracellular steroid hormone receptor signaling pathway; GO:0070887 cellular response to chemical stimulus; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0055114 oxidation-reduction process; GO:0009894 regulation of catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0019725 cellular homeostasis; GO:0023052 signaling; GO:0031323 regulation of cellular metabolic process; GO:0071396 cellular response to lipid; GO:1903506 regulation of nucleic acid-templated transcription; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032870 cellular response to hormone stimulus; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006464 cellular protein modification process; GO:0006082 organic acid metabolic process; GO:0036211 protein modification process; GO:0043436 oxoacid metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0040008 regulation of growth; GO:0009628 response to abiotic stimulus; GO:0060255 regulation of macromolecule metabolic process; GO:0045454 cell redox homeostasis; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0071310 cellular response to organic substance; GO:0044267 cellular protein metabolic process; GO:0043067 regulation of programmed cell death; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0033993 response to lipid; GO:0042592 homeostatic process; GO:0006575 cellular modified amino acid metabolic process; GO:0009889 regulation of biosynthetic process; GO:0009896 positive regulation of catabolic process; GO:0001666 response to hypoxia; GO:0070482 response to oxygen levels; GO:0043620 regulation of DNA-templated transcription in response to stress; GO:0051171 regulation of nitrogen compound metabolic process; GO:0042176 regulation of protein catabolic process; GO:0071453 cellular response to oxygen levels; GO:0009987 cellular process; GO:1901214 regulation of neuron death; GO:0018126 protein hydroxylation; GO:0071456 cellular response to hypoxia; GO:0019511 peptidyl-proline hydroxylation; GO:0006355 regulation of transcription, DNA-templated; GO:0006950 response to stress; GO:0006807 nitrogen compound metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0071407 cellular response to organic cyclic compound; GO:0010033 response to organic substance; GO:1901605 alpha-amino acid metabolic process; GO:0044238 primary metabolic process; GO:0018208 peptidyl-proline modification; GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia; GO:0048518 positive regulation of biological process; GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress; GO:0051252 regulation of RNA metabolic process; GO:0009755 hormone-mediated signaling pathway; GO:0018193 peptidyl-amino acid modification; GO:0051247 positive regulation of protein metabolic process; GO:0051246 regulation of protein metabolic process; GO:0071495 cellular response to endogenous stimulus; GO:0019752 carboxylic acid metabolic process; GO:0045732 positive regulation of protein catabolic process; GO:0036293 response to decreased oxygen levels; GO:0051128 regulation of cellular component organization; GO:0043412 macromolecule modification; GO:0009725 response to hormone; GO:0043401 steroid hormone mediated signaling pathway; GO:0042981 regulation of apoptotic process; GO:0036294 cellular response to decreased oxygen levels; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0044422 organelle part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0019842 vitamin binding; GO:0005506 iron ion binding; GO:0019825 oxygen binding; GO:0031418 L-ascorbic acid binding; GO:0031543 peptidyl-proline dioxygenase activity; GO:0043167 ion binding; GO:0043177 organic acid binding; GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; GO:0005515 protein binding; GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; GO:0048029 monosaccharide binding; GO:0019826 oxygen sensor activity; GO:0016491 oxidoreductase activity; GO:0031406 carboxylic acid binding; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0051213 dioxygenase activity; GO:0005488 binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0030246 carbohydrate binding; GO:0043168 anion binding; GO:0031545 peptidyl-proline 4-dioxygenase activity; GO:0008198 ferrous iron binding; GO:0036094 small molecule binding; ","K09592","EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]","hsa05200 Pathways in cancer - Homo sapiens (human); hsa04066 HIF-1 signaling pathway - Homo sapiens (human); hsa05211 Renal cell carcinoma - Homo sapiens (human); ","IPR006620; IPR005123; ","\"Prolyl 4-hydroxylase, alpha subunit; Oxoglutarate/iron-dependent dioxygenase; \"\r"]
["Q96L46","Calpain small subunit 2 OS=Homo sapiens OX=9606 GN=CAPNS2","CAPNS2",27.66,33.123,26.2,5,8,4,0.953,0.956,0.977,1.004,1.081,1.065,1.091,0.0218,"cytoplasm\r","GO:0016043 cellular component organization; GO:0043062 extracellular structure organization; GO:0022617 extracellular matrix disassembly; GO:0044763 single-organism cellular process; GO:0022411 cellular component disassembly; GO:0044699 single-organism process; GO:0030198 extracellular matrix organization; GO:0009987 cellular process; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0071944 cell periphery; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005886 plasma membrane; GO:0044444 cytoplasmic part; ","GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005509 calcium ion binding; GO:0005488 binding; GO:0043167 ion binding; ","K08584",null,null,"IPR011992; IPR002048; ","EF-hand domain pair; EF-hand domain; \r"]
["Q96LD4","Tripartite motif-containing protein 47 OS=Homo sapiens OX=9606 GN=TRIM47","TRIM47",69.531,13.532,5.6,3,4,3,1.229,0.901,0.777,0.993,1.086,1.024,1.067,0.578,"nucleus\r",null,"GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:0046914 transition metal ion binding; GO:0005488 binding; GO:0043167 ion binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0008270 zinc ion binding; ","K12023",null,null,"IPR001841; IPR013083; IPR001870; IPR013320; IPR000315; ","\"Zinc finger, RING-type; Zinc finger, RING/FYVE/PHD-type; B30.2/SPRY domain; Concanavalin A-like lectin/glucanase domain; B-box-type zinc finger; \"\r"]
["Q96M27","Protein PRRC1 OS=Homo sapiens OX=9606 GN=PRRC1","PRRC1",46.701,24.934,11.2,5,6,5,0.905,0.972,0.926,1.113,1.188,0.9,1.142,0.218,"nucleus\r",null,"GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR026533; ","Non-canonical purine NTP phosphatase/PRRC1; \r"]
["Q96MX6","WD repeat-containing protein 92 OS=Homo sapiens OX=9606 GN=WDR92","WDR92",39.74,1.8777,2,1,1,1,1.158,1.035,0.826,1.131,0.863,1.009,0.995,0.99,"cytoplasm\r","GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0012501 programmed cell death; GO:0009987 cellular process; GO:0008219 cell death; GO:0006915 apoptotic process; ",null,"GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR017986; IPR015943; ","WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain; \r"]
["Q96N67","Dedicator of cytokinesis protein 7 OS=Homo sapiens OX=9606 GN=DOCK7","DOCK7",242.56,7.6502,1.3,3,6,2,0.98,0.923,0.892,1.029,1.051,1.108,1.141,0.0201,"nucleus\r","GO:0044700 single organism signaling; GO:0030335 positive regulation of cell migration; GO:0032270 positive regulation of cellular protein metabolic process; GO:0007420 brain development; GO:0051647 nucleus localization; GO:0032989 cellular component morphogenesis; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0033138 positive regulation of peptidyl-serine phosphorylation; GO:0007399 nervous system development; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0007405 neuroblast proliferation; GO:0044763 single-organism cellular process; GO:0048812 neuron projection morphogenesis; GO:0007163 establishment or maintenance of cell polarity; GO:0051272 positive regulation of cellular component movement; GO:0007264 small GTPase mediated signal transduction; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0000902 cell morphogenesis; GO:0000226 microtubule cytoskeleton organization; GO:0048513 animal organ development; GO:0098722 asymmetric stem cell division; GO:0051336 regulation of hydrolase activity; GO:0007417 central nervous system development; GO:0050790 regulation of catalytic activity; GO:0021846 cell proliferation in forebrain; GO:0010604 positive regulation of macromolecule metabolic process; GO:1904752 regulation of vascular associated smooth muscle cell migration; GO:0051301 cell division; GO:0051640 organelle localization; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0031399 regulation of protein modification process; GO:0055059 asymmetric neuroblast division; GO:2000147 positive regulation of cell motility; GO:0051239 regulation of multicellular organismal process; GO:0072089 stem cell proliferation; GO:0009653 anatomical structure morphogenesis; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0051345 positive regulation of hydrolase activity; GO:2000145 regulation of cell motility; GO:0007409 axonogenesis; GO:0030900 forebrain development; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0036445 neuronal stem cell division; GO:0045196 establishment or maintenance of neuroblast polarity; GO:0051270 regulation of cellular component movement; GO:0043547 positive regulation of GTPase activity; GO:0033135 regulation of peptidyl-serine phosphorylation; GO:0048731 system development; GO:0051960 regulation of nervous system development; GO:0060284 regulation of cell development; GO:0008283 cell proliferation; GO:0030334 regulation of cell migration; GO:0017145 stem cell division; GO:0007017 microtubule-based process; GO:0014911 positive regulation of smooth muscle cell migration; GO:0045165 cell fate commitment; GO:0030182 neuron differentiation; GO:0051247 positive regulation of protein metabolic process; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0048103 somatic stem cell division; GO:0040017 positive regulation of locomotion; GO:0048869 cellular developmental process; GO:0048666 neuron development; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0061351 neural precursor cell proliferation; GO:0007165 signal transduction; GO:0008356 asymmetric cell division; GO:0007154 cell communication; GO:0045200 establishment of neuroblast polarity; GO:0032990 cell part morphogenesis; GO:0009893 positive regulation of metabolic process; GO:0048858 cell projection morphogenesis; GO:0060322 head development; GO:0055057 neuroblast division; GO:0032502 developmental process; GO:0045937 positive regulation of phosphate metabolic process; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0030030 cell projection organization; GO:0065009 regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0016043 cellular component organization; GO:0060255 regulation of macromolecule metabolic process; GO:0050896 response to stimulus; GO:0048468 cell development; GO:1904754 positive regulation of vascular associated smooth muscle cell migration; GO:0000904 cell morphogenesis involved in differentiation; GO:0090630 activation of GTPase activity; GO:0030154 cell differentiation; GO:0030010 establishment of cell polarity; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0035556 intracellular signal transduction; GO:0001932 regulation of protein phosphorylation; GO:0031401 positive regulation of protein modification process; GO:0031175 neuron projection development; GO:0001934 positive regulation of protein phosphorylation; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0051641 cellular localization; GO:0061564 axon development; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0040012 regulation of locomotion; GO:0022027 interkinetic nuclear migration; GO:0014910 regulation of smooth muscle cell migration; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:0050767 regulation of neurogenesis; ","GO:0042995 cell projection; GO:0030054 cell junction; GO:0070161 anchoring junction; GO:0030426 growth cone; GO:0005623 cell; GO:0030427 site of polarized growth; GO:0044463 cell projection part; GO:0030424 axon; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:0043005 neuron projection; GO:0030055 cell-substrate junction; GO:0097458 neuron part; GO:0005924 cell-substrate adherens junction; GO:0045178 basal part of cell; ","GO:0031267 small GTPase binding; GO:0017048 Rho GTPase binding; GO:0048365 Rac GTPase binding; GO:0005085 guanyl-nucleotide exchange factor activity; GO:0017016 Ras GTPase binding; GO:0005488 binding; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0051020 GTPase binding; GO:0019899 enzyme binding; ",{"$nulls":3},"IPR021816; IPR027357; IPR010703; IPR027007; ","\"Dedicator of cytokinesis C/D, N-terminal; DHR-2 domain; Dedicator of cytokinesis, C-terminal; DHR-1 domain; \"\r"]
["Q96NY8","Nectin-4 OS=Homo sapiens OX=9606 GN=NECTIN4","NECTIN4",55.454,7.0137,3.9,2,2,2,0.776,0.997,0.921,1.106,1.097,1.099,1.226,0.106,"extracellular\r","GO:0044409 entry into host; GO:0016043 cellular component organization; GO:0051806 entry into cell of other organism involved in symbiotic interaction; GO:0019058 viral life cycle; GO:0045216 cell-cell junction organization; GO:0044763 single-organism cellular process; GO:0098609 cell-cell adhesion; GO:0044699 single-organism process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0044764 multi-organism cellular process; GO:0051701 interaction with host; GO:0008037 cell recognition; GO:0051704 multi-organism process; GO:0022610 biological adhesion; GO:0030260 entry into host cell; GO:0034330 cell junction organization; GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; GO:0016032 viral process; GO:0051828 entry into other organism involved in symbiotic interaction; GO:0034332 adherens junction organization; GO:0007155 cell adhesion; GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules; GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules; GO:0044419 interspecies interaction between organisms; GO:0009987 cellular process; GO:0046718 viral entry into host cell; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031226 intrinsic component of plasma membrane; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0031982 vesicle; GO:0070161 anchoring junction; GO:0031224 intrinsic component of membrane; GO:0005887 integral component of plasma membrane; GO:0005913 cell-cell adherens junction; GO:0005623 cell; GO:0005911 cell-cell junction; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0044464 cell part; GO:0044425 membrane part; GO:1903561 extracellular vesicle; GO:0005912 adherens junction; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0050839 cell adhesion molecule binding; GO:0060089 molecular transducer activity; GO:0042802 identical protein binding; GO:0004872 receptor activity; GO:0005102 receptor binding; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:0001618 virus receptor activity; ","K06593","PVRL4; poliovirus receptor-related 4","hsa04520 Adherens junction - Homo sapiens (human); ","IPR003598; IPR007110; IPR013783; IPR013162; IPR003599; IPR013106; ","\"Immunoglobulin subtype 2; Immunoglobulin-like domain; Immunoglobulin-like fold; CD80-like, immunoglobulin C2-set; Immunoglobulin subtype; Immunoglobulin V-set domain; \"\r"]
["Q96P70","Importin-9 OS=Homo sapiens OX=9606 GN=IPO9","IPO9",115.96,75.931,11.5,10,11,10,1.016,0.91,0.947,1.028,1.068,0.995,1.076,0.125,"cytoplasm\r","GO:0046907 intracellular transport; GO:0072594 establishment of protein localization to organelle; GO:0017038 protein import; GO:1902593 single-organism nuclear import; GO:0044699 single-organism process; GO:0051169 nuclear transport; GO:0071702 organic substance transport; GO:1902582 single-organism intracellular transport; GO:0015031 protein transport; GO:0051641 cellular localization; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006810 transport; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0051649 establishment of localization in cell; GO:1902578 single-organism localization; GO:0051170 nuclear import; GO:0006886 intracellular protein transport; GO:0044744 protein targeting to nucleus; GO:0006913 nucleocytoplasmic transport; GO:1902580 single-organism cellular localization; GO:0033365 protein localization to organelle; GO:0006606 protein import into nucleus; GO:0051179 localization; GO:0034613 cellular protein localization; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0034504 protein localization to nucleus; GO:0044765 single-organism transport; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; ","GO:0031267 small GTPase binding; GO:0042393 histone binding; GO:0008565 protein transporter activity; GO:0017016 Ras GTPase binding; GO:0005488 binding; GO:0022892 substrate-specific transporter activity; GO:0008536 Ran GTPase binding; GO:0005515 protein binding; GO:0051020 GTPase binding; GO:0019899 enzyme binding; GO:0005215 transporter activity; ","K20224",null,null,"IPR001494; IPR011989; IPR016024; ","\"Importin-beta, N-terminal domain; Armadillo-like helical; Armadillo-type fold; \"\r"]
["Q96PE1","Adhesion G protein-coupled receptor A2 OS=Homo sapiens OX=9606 GN=ADGRA2","ADGRA2",142.65,18.945,2.4,2,2,2,1.061,1.018,1.016,0.919,0.97,1.026,0.942,0.156,"plasma membrane\r","GO:0044700 single organism signaling; GO:0090130 tissue migration; GO:0030335 positive regulation of cell migration; GO:0051674 localization of cell; GO:0009968 negative regulation of signal transduction; GO:0001568 blood vessel development; GO:0007166 cell surface receptor signaling pathway; GO:0040017 positive regulation of locomotion; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0010594 regulation of endothelial cell migration; GO:0001525 angiogenesis; GO:0043542 endothelial cell migration; GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0048514 blood vessel morphogenesis; GO:0002040 sprouting angiogenesis; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0010632 regulation of epithelial cell migration; GO:0044763 single-organism cellular process; GO:0001944 vasculature development; GO:0048522 positive regulation of cellular process; GO:0090287 regulation of cellular response to growth factor stimulus; GO:0048870 cell motility; GO:0051272 positive regulation of cellular component movement; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:1900746 regulation of vascular endothelial growth factor signaling pathway; GO:1902548 negative regulation of cellular response to vascular endothelial growth factor stimulus; GO:0050789 regulation of biological process; GO:0010631 epithelial cell migration; GO:0007417 central nervous system development; GO:0001667 ameboidal-type cell migration; GO:0048583 regulation of response to stimulus; GO:0045765 regulation of angiogenesis; GO:0040011 locomotion; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0072359 circulatory system development; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0016477 cell migration; GO:0010595 positive regulation of endothelial cell migration; GO:2000147 positive regulation of cell motility; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0090132 epithelium migration; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:0009653 anatomical structure morphogenesis; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:2000145 regulation of cell motility; GO:0090288 negative regulation of cellular response to growth factor stimulus; GO:0007275 multicellular organism development; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0009987 cellular process; GO:0009966 regulation of signal transduction; GO:0045595 regulation of cell differentiation; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0060284 regulation of cell development; GO:1901342 regulation of vasculature development; GO:0072358 cardiovascular system development; GO:0030334 regulation of cell migration; GO:0010634 positive regulation of epithelial cell migration; GO:0032101 regulation of response to external stimulus; GO:0090210 regulation of establishment of blood-brain barrier; GO:0048585 negative regulation of response to stimulus; GO:0050920 regulation of chemotaxis; GO:0048518 positive regulation of biological process; GO:0007186 G-protein coupled receptor signaling pathway; GO:1902547 regulation of cellular response to vascular endothelial growth factor stimulus; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0006928 movement of cell or subcellular component; GO:0051179 localization; GO:0040012 regulation of locomotion; GO:0050793 regulation of developmental process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0042995 cell projection; GO:0071944 cell periphery; GO:0044425 membrane part; GO:0044464 cell part; GO:0030175 filopodium; GO:0031224 intrinsic component of membrane; GO:0009986 cell surface; GO:0098858 actin-based cell projection; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; ","GO:0038023 signaling receptor activity; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0005488 binding; GO:0004930 G-protein coupled receptor activity; GO:0005515 protein binding; GO:0004888 transmembrane signaling receptor activity; GO:0004871 signal transducer activity; GO:0099600 transmembrane receptor activity; ","K08461",null,null,"IPR007110; IPR017981; IPR013783; IPR000483; IPR003599; IPR032675; IPR001879; IPR000203; ","\"Immunoglobulin-like domain; GPCR, family 2-like; Immunoglobulin-like fold; Cysteine-rich flanking region, C-terminal; Immunoglobulin subtype; Leucine-rich repeat domain, L domain-like; GPCR, family 2, extracellular hormone receptor domain; GPS motif; \"\r"]
["Q96PK6","RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14","RBM14",69.491,20.475,10.2,6,7,6,0.937,0.971,0.992,0.976,1.091,1.035,1.07,0.14,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0007166 cell surface receptor signaling pathway; GO:0097659 nucleic acid-templated transcription; GO:0009891 positive regulation of biosynthetic process; GO:1902116 negative regulation of organelle assembly; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0010824 regulation of centrosome duplication; GO:0030522 intracellular receptor signaling pathway; GO:0048545 response to steroid hormone; GO:0009719 response to endogenous stimulus; GO:0019538 protein metabolic process; GO:0051493 regulation of cytoskeleton organization; GO:0043170 macromolecule metabolic process; GO:0030518 intracellular steroid hormone receptor signaling pathway; GO:0006476 protein deacetylation; GO:0051716 cellular response to stimulus; GO:0014070 response to organic cyclic compound; GO:0018130 heterocycle biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0071396 cellular response to lipid; GO:0032886 regulation of microtubule-based process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0010948 negative regulation of cell cycle process; GO:0035601 protein deacylation; GO:0042921 glucocorticoid receptor signaling pathway; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0098534 centriole assembly; GO:0006464 cellular protein modification process; GO:1901362 organic cyclic compound biosynthetic process; GO:0046605 regulation of centrosome cycle; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0006260 DNA replication; GO:0006259 DNA metabolic process; GO:0016570 histone modification; GO:0044267 cellular protein metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0016569 covalent chromatin modification; GO:0010826 negative regulation of centrosome duplication; GO:0051254 positive regulation of RNA metabolic process; GO:0006950 response to stress; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0071407 cellular response to organic cyclic compound; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0007017 microtubule-based process; GO:1901576 organic substance biosynthetic process; GO:0006974 cellular response to DNA damage stimulus; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0051276 chromosome organization; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0043412 macromolecule modification; GO:0031328 positive regulation of cellular biosynthetic process; GO:0051129 negative regulation of cellular component organization; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0071383 cellular response to steroid hormone stimulus; GO:1902115 regulation of organelle assembly; GO:0046599 regulation of centriole replication; GO:0030520 intracellular estrogen receptor signaling pathway; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0051726 regulation of cell cycle; GO:0098732 macromolecule deacylation; GO:0006310 DNA recombination; GO:0070887 cellular response to chemical stimulus; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0051494 negative regulation of cytoskeleton organization; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0016070 RNA metabolic process; GO:0010639 negative regulation of organelle organization; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0032870 cellular response to hormone stimulus; GO:0060395 SMAD protein signal transduction; GO:0019222 regulation of metabolic process; GO:0046606 negative regulation of centrosome cycle; GO:0006325 chromatin organization; GO:0036211 protein modification process; GO:0016043 cellular component organization; GO:0045786 negative regulation of cell cycle; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044087 regulation of cellular component biogenesis; GO:0050896 response to stimulus; GO:0031958 corticosteroid receptor signaling pathway; GO:0071704 organic substance metabolic process; GO:0033993 response to lipid; GO:0070925 organelle assembly; GO:0034641 cellular nitrogen compound metabolic process; GO:0046600 negative regulation of centriole replication; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0016575 histone deacetylation; GO:0070507 regulation of microtubule cytoskeleton organization; GO:0006355 regulation of transcription, DNA-templated; GO:0006807 nitrogen compound metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0033043 regulation of organelle organization; GO:0010556 regulation of macromolecule biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0009755 hormone-mediated signaling pathway; GO:0044249 cellular biosynthetic process; GO:0006281 DNA repair; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0071495 cellular response to endogenous stimulus; GO:0010467 gene expression; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0051128 regulation of cellular component organization; GO:0009725 response to hormone; GO:0043401 steroid hormone mediated signaling pathway; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005730 nucleolus; GO:0016604 nuclear body; GO:0005667 transcription factor complex; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0016592 mediator complex; GO:0016607 nuclear speck; GO:0005622 intracellular; GO:0044464 cell part; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0003723 RNA binding; GO:1901265 nucleoside phosphate binding; GO:0030674 protein binding, bridging; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0003712 transcription cofactor activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding; GO:0001104 RNA polymerase II transcription cofactor activity; GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0060090 binding, bridging; GO:0003713 transcription coactivator activity; GO:0000988 transcription factor activity, protein binding; GO:0036094 small molecule binding; ","K13189",null,null,"IPR000504; IPR012677; ","RNA recognition motif domain; Nucleotide-binding alpha-beta plait domain; \r"]
["Q96Q06","Perilipin-4 OS=Homo sapiens OX=9606 GN=PLIN4","PLIN4",134.43,323.31,66.2,51,94,51,1.317,1.295,1.282,0.682,0.713,0.727,0.545,3.85e-06,"mitochondria\r",null,"GO:0016020 membrane; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005886 plasma membrane; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0005811 lipid particle; GO:0044444 cytoplasmic part; ",null,"K20254","PLIN4; perilipin-4","hsa03320 PPAR signaling pathway - Homo sapiens (human); "]
["Q96Q11","CCA tRNA nucleotidyltransferase 1, mitochondrial OS=Homo sapiens OX=9606 GN=TRNT1","TRNT1",50.127,5.4327,4.1,2,3,2,0.936,0.996,0.953,1.033,1.003,1.054,1.071,0.0425,"mitochondria\r","GO:0042780 tRNA 3'-end processing; GO:0031123 RNA 3'-end processing; GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0072594 establishment of protein localization to organelle; GO:0006725 cellular aromatic compound metabolic process; GO:0006839 mitochondrial transport; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0071704 organic substance metabolic process; GO:0043628 ncRNA 3'-end processing; GO:0006605 protein targeting; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0007005 mitochondrion organization; GO:0090646 mitochondrial tRNA processing; GO:0006886 intracellular protein transport; GO:0006626 protein targeting to mitochondrion; GO:0034641 cellular nitrogen compound metabolic process; GO:0033365 protein localization to organelle; GO:0043170 macromolecule metabolic process; GO:0034613 cellular protein localization; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0009987 cellular process; GO:0034470 ncRNA processing; GO:0006396 RNA processing; GO:0000959 mitochondrial RNA metabolic process; GO:0000963 mitochondrial RNA processing; GO:1990180 mitochondrial tRNA 3'-end processing; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0071702 organic substance transport; GO:0070585 protein localization to mitochondrion; GO:0044238 primary metabolic process; GO:0051641 cellular localization; GO:0006810 transport; GO:0045184 establishment of protein localization; GO:0016070 RNA metabolic process; GO:0070727 cellular macromolecule localization; GO:0006399 tRNA metabolic process; GO:0090304 nucleic acid metabolic process; GO:0006996 organelle organization; GO:0008033 tRNA processing; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0051179 localization; GO:0072655 establishment of protein localization to mitochondrion; GO:0034660 ncRNA metabolic process; GO:0000965 mitochondrial RNA 3'-end processing; GO:0001680 tRNA 3'-terminal CCA addition; GO:0071840 cellular component organization or biogenesis; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0034062 5'-3' RNA polymerase activity; GO:0097747 RNA polymerase activity; GO:0052929 ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0000049 tRNA binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0052927 CTP:tRNA cytidylyltransferase activity; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003723 RNA binding; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0004810 tRNA adenylyltransferase activity; GO:0070566 adenylyltransferase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016779 nucleotidyltransferase activity; GO:0003676 nucleic acid binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0052928 CTP:3'-cytidine-tRNA cytidylyltransferase activity; GO:0036094 small molecule binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K00974","cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]","hsa03013 RNA transport - Homo sapiens (human); ","IPR032828; IPR002646; ","\"tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain; Poly A polymerase, head domain; \"\r"]
["Q96QK1","Vacuolar protein sorting-associated protein 35 OS=Homo sapiens OX=9606 GN=VPS35","VPS35",91.706,178.42,33.3,24,40,24,1.034,1.003,1.039,0.992,0.963,0.994,0.959,0.0489,"cytoplasm\r","GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0007166 cell surface receptor signaling pathway; GO:0009891 positive regulation of biosynthetic process; GO:0090002 establishment of protein localization to plasma membrane; GO:0032459 regulation of protein oligomerization; GO:0010821 regulation of mitochondrion organization; GO:0015031 protein transport; GO:0050807 regulation of synapse organization; GO:1903364 positive regulation of cellular protein catabolic process; GO:1903336 negative regulation of vacuolar transport; GO:1905166 negative regulation of lysosomal protein catabolic process; GO:0032879 regulation of localization; GO:0090263 positive regulation of canonical Wnt signaling pathway; GO:0099074 mitochondrion to lysosome transport; GO:0033365 protein localization to organelle; GO:0090140 regulation of mitochondrial fission; GO:0016055 Wnt signaling pathway; GO:0008104 protein localization; GO:0031333 negative regulation of protein complex assembly; GO:1903362 regulation of cellular protein catabolic process; GO:0044765 single-organism transport; GO:0051051 negative regulation of transport; GO:0051716 cellular response to stimulus; GO:0042069 regulation of catecholamine metabolic process; GO:0072657 protein localization to membrane; GO:0032460 negative regulation of protein oligomerization; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0050879 multicellular organismal movement; GO:0060828 regulation of canonical Wnt signaling pathway; GO:0007009 plasma membrane organization; GO:0098877 neurotransmitter receptor transport to plasma membrane; GO:0031323 regulation of cellular metabolic process; GO:0010506 regulation of autophagy; GO:0032501 multicellular organismal process; GO:0016241 regulation of macroautophagy; GO:0006810 transport; GO:0042147 retrograde transport, endosome to Golgi; GO:0007267 cell-cell signaling; GO:0032269 negative regulation of cellular protein metabolic process; GO:0090326 positive regulation of locomotion involved in locomotory behavior; GO:0048583 regulation of response to stimulus; GO:0050714 positive regulation of protein secretion; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051223 regulation of protein transport; GO:0061357 positive regulation of Wnt protein secretion; GO:0051094 positive regulation of developmental process; GO:0060548 negative regulation of cell death; GO:0051047 positive regulation of secretion; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0044707 single-multicellular organism process; GO:0050795 regulation of behavior; GO:0060161 positive regulation of dopamine receptor signaling pathway; GO:0048520 positive regulation of behavior; GO:2000331 regulation of terminal button organization; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:1990778 protein localization to cell periphery; GO:0099637 neurotransmitter receptor transport; GO:0060341 regulation of cellular localization; GO:1903335 regulation of vacuolar transport; GO:1902578 single-organism localization; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0009896 positive regulation of catabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902580 single-organism cellular localization; GO:0032880 regulation of protein localization; GO:0042176 regulation of protein catabolic process; GO:0034613 cellular protein localization; GO:0090150 establishment of protein localization to membrane; GO:0009966 regulation of signal transduction; GO:0043653 mitochondrial fragmentation involved in apoptotic process; GO:1901215 negative regulation of neuron death; GO:1904351 negative regulation of protein catabolic process in the vacuole; GO:0099638 endosome to plasma membrane protein transport; GO:0016192 vesicle-mediated transport; GO:0032462 regulation of protein homooligomerization; GO:0071702 organic substance transport; GO:0009892 negative regulation of metabolic process; GO:0045184 establishment of protein localization; GO:0031330 negative regulation of cellular catabolic process; GO:0072659 protein localization to plasma membrane; GO:0051247 positive regulation of protein metabolic process; GO:1904951 positive regulation of establishment of protein localization; GO:0030111 regulation of Wnt signaling pathway; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0031325 positive regulation of cellular metabolic process; GO:0030177 positive regulation of Wnt signaling pathway; GO:0080171 lytic vacuole organization; GO:0031647 regulation of protein stability; GO:0012501 programmed cell death; GO:0031328 positive regulation of cellular biosynthetic process; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:1903827 regulation of cellular protein localization; GO:1905165 regulation of lysosomal protein catabolic process; GO:0010256 endomembrane system organization; GO:0090325 regulation of locomotion involved in locomotory behavior; GO:0040017 positive regulation of locomotion; GO:0042053 regulation of dopamine metabolic process; GO:0051129 negative regulation of cellular component organization; GO:0023051 regulation of signaling; GO:0031331 positive regulation of cellular catabolic process; GO:0006839 mitochondrial transport; GO:0051046 regulation of secretion; GO:0044699 single-organism process; GO:0045915 positive regulation of catecholamine metabolic process; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0099075 mitochondrion-derived vesicle mediated transport; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0006915 apoptotic process; GO:0007005 mitochondrion organization; GO:1990126 retrograde transport, endosome to plasma membrane; GO:0007033 vacuole organization; GO:0033036 macromolecule localization; GO:0010468 regulation of gene expression; GO:1903828 negative regulation of cellular protein localization; GO:0031326 regulation of cellular biosynthetic process; GO:0033240 positive regulation of cellular amine metabolic process; GO:0061356 regulation of Wnt protein secretion; GO:0008277 regulation of G-protein coupled receptor protein signaling pathway; GO:0048522 positive regulation of cellular process; GO:1903530 regulation of secretion by cell; GO:1903363 negative regulation of cellular protein catabolic process; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051050 positive regulation of transport; GO:0007040 lysosome organization; GO:0198738 cell-cell signaling by wnt; GO:0016197 endosomal transport; GO:0090141 positive regulation of mitochondrial fission; GO:0060159 regulation of dopamine receptor signaling pathway; GO:0043254 regulation of protein complex assembly; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:1903532 positive regulation of secretion by cell; GO:0010638 positive regulation of organelle organization; GO:1902822 regulation of late endosome to lysosome transport; GO:0045964 positive regulation of dopamine metabolic process; GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway; GO:0019222 regulation of metabolic process; GO:0051222 positive regulation of protein transport; GO:1903181 positive regulation of dopamine biosynthetic process; GO:0016043 cellular component organization; GO:0042177 negative regulation of protein catabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0044087 regulation of cellular component biogenesis; GO:0031344 regulation of cell projection organization; GO:0031324 negative regulation of cellular metabolic process; GO:1903179 regulation of dopamine biosynthetic process; GO:0050882 voluntary musculoskeletal movement; GO:0050896 response to stimulus; GO:0070201 regulation of establishment of protein localization; GO:0023056 positive regulation of signaling; GO:1902823 negative regulation of late endosome to lysosome transport; GO:0050881 musculoskeletal movement; GO:0009895 negative regulation of catabolic process; GO:0010647 positive regulation of cell communication; GO:0050708 regulation of protein secretion; GO:0016482 cytosolic transport; GO:0009987 cellular process; GO:0033238 regulation of cellular amine metabolic process; GO:1902950 regulation of dendritic spine maintenance; GO:1901214 regulation of neuron death; GO:0007041 lysosomal transport; GO:0050803 regulation of synapse structure or activity; GO:0098876 vesicle-mediated transport to the plasma membrane; GO:0008637 apoptotic mitochondrial changes; GO:0010629 negative regulation of gene expression; GO:0051049 regulation of transport; GO:0044802 single-organism membrane organization; GO:0033043 regulation of organelle organization; GO:0048518 positive regulation of biological process; GO:0031648 protein destabilization; GO:1904350 regulation of protein catabolic process in the vacuole; GO:0010822 positive regulation of mitochondrion organization; GO:0051641 cellular localization; GO:0070727 cellular macromolecule localization; GO:0008219 cell death; GO:0051246 regulation of protein metabolic process; GO:0007034 vacuolar transport; GO:0032463 negative regulation of protein homooligomerization; GO:0022603 regulation of anatomical structure morphogenesis; GO:0051248 negative regulation of protein metabolic process; GO:0099639 neurotransmitter receptor transport, endosome to plasma membrane; GO:0045732 positive regulation of protein catabolic process; GO:0009967 positive regulation of signal transduction; GO:0051128 regulation of cellular component organization; GO:0040012 regulation of locomotion; GO:0045056 transcytosis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0030904 retromer complex; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0030906 retromer, cargo-selective complex; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0043025 neuronal cell body; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0032279 asymmetric synapse; GO:0044422 organelle part; GO:0005769 early endosome; GO:0005765 lysosomal membrane; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0098805 whole membrane; GO:0005764 lysosome; GO:0014069 postsynaptic density; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0048471 perinuclear region of cytoplasm; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0098984 neuron to neuron synapse; GO:0044456 synapse part; GO:0000323 lytic vacuole; GO:0010008 endosome membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0097422 tubular endosome; GO:0042995 cell projection; GO:0005770 late endosome; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0044440 endosomal part; GO:0012505 endomembrane system; GO:0099073 mitochondrion-derived vesicle; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0045202 synapse; GO:0098852 lytic vacuole membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0098794 postsynapse; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0044297 cell body; GO:0099572 postsynaptic specialization; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0008565 protein transporter activity; GO:0005102 receptor binding; GO:0005488 binding; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0001664 G-protein coupled receptor binding; GO:0031748 D1 dopamine receptor binding; GO:0050780 dopamine receptor binding; GO:0005215 transporter activity; ","K18468","VPS35; vacuolar protein sorting-associated protein 35","hsa04144 Endocytosis - Homo sapiens (human); ","IPR016024; ","Armadillo-type fold; \r"]
["Q96RF0","Sorting nexin-18 OS=Homo sapiens OX=9606 GN=SNX18","SNX18",68.894,9.1362,4.3,2,2,2,0.901,1.034,0.97,1.091,0.994,1.017,1.068,0.244,"nucleus\r","GO:0016043 cellular component organization; GO:0007067 mitotic nuclear division; GO:0048285 organelle fission; GO:0010324 membrane invagination; GO:0044699 single-organism process; GO:0032506 cytokinetic process; GO:1903047 mitotic cell cycle process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0099024 plasma membrane invagination; GO:0000910 cytokinesis; GO:0051345 positive regulation of hydrolase activity; GO:0044093 positive regulation of molecular function; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0009987 cellular process; GO:0000278 mitotic cell cycle; GO:0043547 positive regulation of GTPase activity; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0000281 mitotic cytokinesis; GO:0071702 organic substance transport; GO:0006897 endocytosis; GO:0043085 positive regulation of catalytic activity; GO:0016197 endosomal transport; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:0036089 cleavage furrow formation; GO:0051336 regulation of hydrolase activity; GO:0061640 cytoskeleton-dependent cytokinesis; GO:0006996 organelle organization; GO:0050790 regulation of catalytic activity; GO:0061024 membrane organization; GO:0065009 regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0000280 nuclear division; GO:0022402 cell cycle process; GO:0051301 cell division; GO:0051179 localization; GO:0007049 cell cycle; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0019898 extrinsic component of membrane; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0031234 extrinsic component of cytoplasmic side of plasma membrane; GO:0005623 cell; GO:0009898 cytoplasmic side of plasma membrane; GO:0098562 cytoplasmic side of membrane; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0098552 side of membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0010008 endosome membrane; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0019897 extrinsic component of plasma membrane; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901981 phosphatidylinositol phosphate binding; GO:0005546 phosphatidylinositol-4,5-bisphosphate binding; GO:0005488 binding; GO:0005543 phospholipid binding; GO:0035091 phosphatidylinositol binding; GO:0043167 ion binding; GO:0008289 lipid binding; GO:0043168 anion binding; GO:0005515 protein binding; GO:1902936 phosphatidylinositol bisphosphate binding; ","K17923",null,null,"IPR001452; IPR019497; IPR001683; ","\"SH3 domain; Sorting nexin protein, WASP-binding domain; Phox homologous domain; \"\r"]
["Q96RQ3","Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC1","MCCC1",80.472,30.387,9.5,6,8,6,1.14,1.196,1.124,0.817,0.817,0.898,0.732,0.00104,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:1901606 alpha-amino acid catabolic process; GO:0016043 cellular component organization; GO:0006768 biotin metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0051259 protein oligomerization; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0006766 vitamin metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0046483 heterocycle metabolic process; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0044248 cellular catabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009081 branched-chain amino acid metabolic process; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0006767 water-soluble vitamin metabolic process; GO:0006790 sulfur compound metabolic process; GO:0071822 protein complex subunit organization; GO:0044712 single-organism catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0044282 small molecule catabolic process; GO:0043603 cellular amide metabolic process; GO:1901605 alpha-amino acid metabolic process; GO:0044238 primary metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0051186 cofactor metabolic process; GO:0046395 carboxylic acid catabolic process; GO:0051291 protein heterooligomerization; GO:0009083 branched-chain amino acid catabolic process; GO:1901575 organic substance catabolic process; GO:0006551 leucine metabolic process; GO:1901565 organonitrogen compound catabolic process; GO:0044710 single-organism metabolic process; GO:0016054 organic acid catabolic process; GO:0019752 carboxylic acid metabolic process; GO:0006552 leucine catabolic process; GO:0009063 cellular amino acid catabolic process; GO:0006082 organic acid metabolic process; GO:0070271 protein complex biogenesis; GO:0009056 catabolic process; GO:0043436 oxoacid metabolic process; GO:0071840 cellular component organization or biogenesis; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0031090 organelle membrane; GO:0031967 organelle envelope; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0031975 envelope; GO:0019866 organelle inner membrane; GO:1905202 methylcrotonoyl-CoA carboxylase complex; GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0004485 methylcrotonoyl-CoA carboxylase activity; GO:1901265 nucleoside phosphate binding; GO:0016885 ligase activity, forming carbon-carbon bonds; GO:0016874 ligase activity; GO:0005515 protein binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0031406 carboxylic acid binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0019842 vitamin binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0043177 organic acid binding; GO:0033218 amide binding; GO:0000166 nucleotide binding; GO:0033293 monocarboxylic acid binding; GO:1901681 sulfur compound binding; GO:0016879 ligase activity, forming carbon-nitrogen bonds; GO:0032549 ribonucleoside binding; GO:0004075 biotin carboxylase activity; GO:0097367 carbohydrate derivative binding; GO:0016421 CoA carboxylase activity; GO:0009374 biotin binding; GO:0046872 metal ion binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; ","K01968","E6.4.1.4A; 3-methylcrotonyl-CoA carboxylase alpha subunit [EC:6.4.1.4]","hsa00280 Valine, leucine and isoleucine degradation - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR011053; IPR005481; IPR005479; IPR000089; IPR013815; IPR016185; IPR011764; IPR005482; IPR011761; IPR013816; IPR011054; ","\"Single hybrid motif; Biotin carboxylase-like, N-terminal domain; Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain; Biotin/lipoyl attachment; ATP-grasp fold, subdomain 1; Pre-ATP-grasp domain; Biotin carboxylation domain; Biotin carboxylase, C-terminal; ATP-grasp fold; ATP-grasp fold, subdomain 2; Rudiment single hybrid motif; \"\r"]
["Q96RS6","NudC domain-containing protein 1 OS=Homo sapiens OX=9606 GN=NUDCD1","NUDCD1",66.755,5.5443,3.8,2,2,2,0.994,0.954,0.806,0.965,1.112,1.166,1.178,0.128,"cytoplasm\r","GO:0002376 immune system process; ","GO:0043229 intracellular organelle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR007052; IPR008978; ","CS domain; HSP20-like chaperone; \r"]
["Q96S15","GATOR complex protein WDR24 OS=Homo sapiens OX=9606 GN=WDR24","WDR24",101.99,1.7691,0.9,1,1,1,1.012,0.838,1.059,1.061,1.041,0.991,1.063,0.426,"nucleus\r","GO:0050794 regulation of cellular process; GO:0034198 cellular response to amino acid starvation; GO:0033554 cellular response to stress; GO:0009267 cellular response to starvation; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0006914 autophagy; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0031669 cellular response to nutrient levels; GO:0032006 regulation of TOR signaling; GO:0009605 response to external stimulus; GO:0009991 response to extracellular stimulus; GO:0008152 metabolic process; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0023056 positive regulation of signaling; GO:0044248 cellular catabolic process; GO:0010647 positive regulation of cell communication; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:0051716 cellular response to stimulus; GO:1902531 regulation of intracellular signal transduction; GO:0006950 response to stress; GO:0031329 regulation of cellular catabolic process; GO:0032008 positive regulation of TOR signaling; GO:0009894 regulation of catabolic process; GO:0048522 positive regulation of cellular process; GO:0071496 cellular response to external stimulus; GO:0031323 regulation of cellular metabolic process; GO:0048518 positive regulation of biological process; GO:0010506 regulation of autophagy; GO:0031668 cellular response to extracellular stimulus; GO:0050789 regulation of biological process; GO:0048583 regulation of response to stimulus; GO:0019222 regulation of metabolic process; GO:0042594 response to starvation; GO:0009967 positive regulation of signal transduction; GO:0031667 response to nutrient levels; GO:0048584 positive regulation of response to stimulus; GO:0009056 catabolic process; GO:0065007 biological regulation; ","GO:0032991 macromolecular complex; GO:0043234 protein complex; GO:0061700 GATOR2 complex; GO:0035859 Seh1-associated complex; ","GO:0005515 protein binding; GO:0005488 binding; ","K20408","WDR24; WD repeat-containing protein 24","hsa04150 mTOR signaling pathway - Homo sapiens (human); ","IPR017986; IPR015943; ","WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain; \r"]
["Q96S52","GPI transamidase component PIG-S OS=Homo sapiens OX=9606 GN=PIGS","PIGS",61.655,12.328,3.8,2,2,2,1.084,0.944,0.965,1.026,0.949,1.041,1.008,0.874,"endoplasmic reticulum\r","GO:0006506 GPI anchor biosynthetic process; GO:0009247 glycolipid biosynthetic process; GO:1903509 liposaccharide metabolic process; GO:0046486 glycerolipid metabolic process; GO:0006661 phosphatidylinositol biosynthetic process; GO:0006643 membrane lipid metabolic process; GO:0008654 phospholipid biosynthetic process; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0042157 lipoprotein metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0008610 lipid biosynthetic process; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0016255 attachment of GPI anchor to protein; GO:0006505 GPI anchor metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0006650 glycerophospholipid metabolic process; GO:0046488 phosphatidylinositol metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0042158 lipoprotein biosynthetic process; GO:0046467 membrane lipid biosynthetic process; GO:0006629 lipid metabolic process; GO:0044711 single-organism biosynthetic process; GO:0044763 single-organism cellular process; GO:0006664 glycolipid metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0045017 glycerolipid biosynthetic process; GO:0090407 organophosphate biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0046474 glycerophospholipid biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0019637 organophosphate metabolic process; GO:0006464 cellular protein modification process; GO:0006497 protein lipidation; GO:0006644 phospholipid metabolic process; GO:0036211 protein modification process; GO:0043412 macromolecule modification; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:1902494 catalytic complex; GO:0044432 endoplasmic reticulum part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0031227 intrinsic component of endoplasmic reticulum membrane; GO:0042765 GPI-anchor transamidase complex; GO:0030176 integral component of endoplasmic reticulum membrane; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0003923 GPI-anchor transamidase activity; GO:0016787 hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; ","K05291","PIGS; phosphatidylinositol glycan, class S","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis - Homo sapiens (human); "]
["Q96SB4","SRSF protein kinase 1 OS=Homo sapiens OX=9606 GN=SRPK1","SRPK1",74.324,6.1805,1.7,1,4,1,0.879,0.829,0.732,1.182,1.258,1.108,1.454,0.0045,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0022613 ribonucleoprotein complex biogenesis; GO:0022618 ribonucleoprotein complex assembly; GO:0022414 reproductive process; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0071826 ribonucleoprotein complex subunit organization; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0007286 spermatid development; GO:0065003 macromolecular complex assembly; GO:0044702 single organism reproductive process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0048024 regulation of mRNA splicing, via spliceosome; GO:0071103 DNA conformation change; GO:0006396 RNA processing; GO:0048525 negative regulation of viral process; GO:0032502 developmental process; GO:1903902 positive regulation of viral life cycle; GO:0010468 regulation of gene expression; GO:0051716 cellular response to stimulus; GO:0043902 positive regulation of multi-organism process; GO:0003006 developmental process involved in reproduction; GO:0007059 chromosome segregation; GO:0080090 regulation of primary metabolic process; GO:0019953 sexual reproduction; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0050684 regulation of mRNA processing; GO:0045069 regulation of viral genome replication; GO:0031323 regulation of cellular metabolic process; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0022412 cellular process involved in reproduction in multicellular organism; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006464 cellular protein modification process; GO:0006952 defense response; GO:0006325 chromatin organization; GO:0036211 protein modification process; GO:0016071 mRNA metabolic process; GO:0048609 multicellular organismal reproductive process; GO:0048856 anatomical structure development; GO:0050794 regulation of cellular process; GO:0000003 reproduction; GO:0016310 phosphorylation; GO:0006997 nucleus organization; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0035092 sperm chromatin condensation; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:0045087 innate immune response; GO:0048468 cell development; GO:0071704 organic substance metabolic process; GO:1903901 negative regulation of viral life cycle; GO:0000398 mRNA splicing, via spliceosome; GO:0030154 cell differentiation; GO:0006323 DNA packaging; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0006468 protein phosphorylation; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0016032 viral process; GO:0000375 RNA splicing, via transesterification reactions; GO:0007281 germ cell development; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0008380 RNA splicing; GO:0045070 positive regulation of viral genome replication; GO:0009987 cellular process; GO:0034622 cellular macromolecular complex assembly; GO:0006950 response to stress; GO:0048232 male gamete generation; GO:0035556 intracellular signal transduction; GO:0007283 spermatogenesis; GO:0043900 regulation of multi-organism process; GO:0050792 regulation of viral process; GO:0006807 nitrogen compound metabolic process; GO:0002376 immune system process; GO:0045071 negative regulation of viral genome replication; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0007276 gamete generation; GO:0043933 macromolecular complex subunit organization; GO:0043901 negative regulation of multi-organism process; GO:0043484 regulation of RNA splicing; GO:0032504 multicellular organism reproduction; GO:1903311 regulation of mRNA metabolic process; GO:0048524 positive regulation of viral process; GO:0051276 chromosome organization; GO:0006793 phosphorus metabolic process; GO:0007289 spermatid nucleus differentiation; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0044703 multi-organism reproductive process; GO:0048515 spermatid differentiation; GO:0010467 gene expression; GO:0043412 macromolecule modification; GO:0006955 immune response; GO:1903900 regulation of viral life cycle; GO:0000245 spliceosomal complex assembly; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0043229 intracellular organelle; GO:0005783 endoplasmic reticulum; GO:0071944 cell periphery; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0005886 plasma membrane; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0016363 nuclear matrix; GO:0034399 nuclear periphery; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0005515 protein binding; GO:0004672 protein kinase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016301 kinase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0000287 magnesium ion binding; GO:0003723 RNA binding; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003676 nucleic acid binding; GO:0046872 metal ion binding; GO:0004674 protein serine/threonine kinase activity; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0036094 small molecule binding; ","K15409","SRPK1; serine/threonine-protein kinase SRPK1 [EC:2.7.11.1]","hsa05168 Herpes simplex infection - Homo sapiens (human); ","IPR000719; IPR011009; ","Protein kinase domain; Protein kinase-like domain; \r"]
["Q96SQ9","Cytochrome P450 2S1 OS=Homo sapiens OX=9606 GN=CYP2S1","CYP2S1",55.816,11.204,5,2,2,2,1.113,1.134,1.022,1.033,0.756,0.969,0.844,0.151,"extracellular\r","GO:0033559 unsaturated fatty acid metabolic process; GO:0019369 arachidonic acid metabolic process; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901568 fatty acid derivative metabolic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0006631 fatty acid metabolic process; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0019373 epoxygenase P450 pathway; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0001676 long-chain fatty acid metabolic process; GO:0044710 single-organism metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0006082 organic acid metabolic process; GO:0009987 cellular process; GO:0043436 oxoacid metabolic process; GO:0006690 icosanoid metabolic process; GO:0006629 lipid metabolic process; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044432 endoplasmic reticulum part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; ","GO:0008391 arachidonic acid monooxygenase activity; GO:0005506 iron ion binding; GO:0008392 arachidonic acid epoxygenase activity; GO:0043167 ion binding; GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; GO:0005515 protein binding; GO:0016491 oxidoreductase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0020037 heme binding; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0008401 retinoic acid 4-hydroxylase activity; GO:0070330 aromatase activity; GO:0046906 tetrapyrrole binding; GO:0004497 monooxygenase activity; GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; ","K07420","CYP2S1; cytochrome P450 family 2 subfamily S polypeptide 1 [EC:1.14.14.1]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00980 Metabolism of xenobiotics by cytochrome P450 - Homo sapiens (human); hsa00830 Retinol metabolism - Homo sapiens (human); "]
["Q96T76","MMS19 nucleotide excision repair protein homolog OS=Homo sapiens OX=9606 GN=MMS19","MMS19",113.29,8.5587,4.5,4,4,4,0.834,0.952,0.913,1.115,1.002,1.142,1.207,0.0282,"endoplasmic reticulum\r","GO:0044085 cellular component biogenesis; GO:0051188 cofactor biosynthetic process; GO:0044700 single organism signaling; GO:0097659 nucleic acid-templated transcription; GO:0006289 nucleotide-excision repair; GO:0009891 positive regulation of biosynthetic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0009719 response to endogenous stimulus; GO:0043170 macromolecule metabolic process; GO:0006790 sulfur compound metabolic process; GO:0051716 cellular response to stimulus; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0007059 chromosome segregation; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0023052 signaling; GO:0031323 regulation of cellular metabolic process; GO:0051186 cofactor metabolic process; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0033554 cellular response to stress; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0006259 DNA metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0031163 metallo-sulfur cluster assembly; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0016226 iron-sulfur cluster assembly; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0051254 positive regulation of RNA metabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0006950 response to stress; GO:0035556 intracellular signal transduction; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0000160 phosphorelay signal transduction system; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0006974 cellular response to DNA damage stimulus; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0006281 DNA repair; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0031325 positive regulation of cellular metabolic process; GO:0010467 gene expression; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0009725 response to hormone; GO:0031328 positive regulation of cellular biosynthetic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0061695 transferase complex, transferring phosphorus-containing groups; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:1902554 serine/threonine protein kinase complex; GO:0005623 cell; GO:1902911 protein kinase complex; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0005675 holo TFIIH complex; GO:0044445 cytosolic part; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0055029 nuclear DNA-directed RNA polymerase complex; GO:0000428 DNA-directed RNA polymerase complex; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0030880 RNA polymerase complex; GO:0031981 nuclear lumen; GO:1990234 transferase complex; GO:0044798 nuclear transcription factor complex; GO:0005667 transcription factor complex; GO:0005829 cytosol; GO:0005819 spindle; GO:0016591 DNA-directed RNA polymerase II, holoenzyme; GO:0090575 RNA polymerase II transcription factor complex; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0032806 carboxy-terminal domain protein kinase complex; GO:0071817 MMXD complex; GO:0043234 protein complex; GO:0097361 CIA complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0030331 estrogen receptor binding; GO:0030674 protein binding, bridging; GO:0005102 receptor binding; GO:0005515 protein binding; GO:0051427 hormone receptor binding; GO:0003712 transcription cofactor activity; GO:0032947 protein complex scaffold; GO:0005488 binding; GO:0035258 steroid hormone receptor binding; GO:0035257 nuclear hormone receptor binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0030159 receptor signaling complex scaffold activity; GO:0060090 binding, bridging; GO:0003713 transcription coactivator activity; GO:0005198 structural molecule activity; GO:0000988 transcription factor activity, protein binding; GO:0019899 enzyme binding; ","K15075",null,null,"IPR011989; IPR016024; IPR024687; ","\"Armadillo-like helical; Armadillo-type fold; MMS19, C-terminal; \"\r"]
["Q96TC7","Regulator of microtubule dynamics protein 3 OS=Homo sapiens OX=9606 GN=RMDN3","RMDN3",52.118,10.038,7.2,3,3,3,1.019,0.946,1.092,1.022,0.962,0.968,0.966,0.503,"mitochondria\r","GO:0032502 developmental process; GO:0065008 regulation of biological quality; GO:0072503 cellular divalent inorganic cation homeostasis; GO:0050801 ion homeostasis; GO:0055074 calcium ion homeostasis; GO:0030003 cellular cation homeostasis; GO:0048869 cellular developmental process; GO:0098771 inorganic ion homeostasis; GO:0044763 single-organism cellular process; GO:0019725 cellular homeostasis; GO:0044699 single-organism process; GO:0006874 cellular calcium ion homeostasis; GO:0055082 cellular chemical homeostasis; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:0055080 cation homeostasis; GO:0006873 cellular ion homeostasis; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0006915 apoptotic process; GO:0055065 metal ion homeostasis; GO:0006875 cellular metal ion homeostasis; GO:0012501 programmed cell death; GO:0072507 divalent inorganic cation homeostasis; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0019867 outer membrane; GO:0005874 microtubule; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005740 mitochondrial envelope; GO:0005856 cytoskeleton; GO:0015630 microtubule cytoskeleton; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0031968 organelle outer membrane; GO:0043227 membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0000922 spindle pole; GO:0099513 polymeric cytoskeletal fiber; GO:0098588 bounding membrane of organelle; GO:0044429 mitochondrial part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0005741 mitochondrial outer membrane; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0016021 integral component of membrane; GO:0005819 spindle; GO:0005739 mitochondrion; GO:0099081 supramolecular polymer; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0031975 envelope; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR011990; ","Tetratricopeptide-like helical domain; \r"]
["Q99439","Calponin-2 OS=Homo sapiens OX=9606 GN=CNN2","CNN2",33.697,35.065,23,6,12,5,0.912,0.968,0.896,1.128,1.07,1.029,1.162,0.0132,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0071260 cellular response to mechanical stimulus; GO:0045321 leukocyte activation; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0009628 response to abiotic stimulus; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0051234 establishment of localization; GO:0009612 response to mechanical stimulus; GO:0009605 response to external stimulus; GO:0030036 actin cytoskeleton organization; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0036230 granulocyte activation; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0031032 actomyosin structure organization; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0071214 cellular response to abiotic stimulus; GO:0002446 neutrophil mediated immunity; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0002376 immune system process; GO:0071496 cellular response to external stimulus; GO:0032970 regulation of actin filament-based process; GO:0043312 neutrophil degranulation; GO:0002263 cell activation involved in immune response; GO:0002444 myeloid leukocyte mediated immunity; GO:0006810 transport; GO:0002366 leukocyte activation involved in immune response; GO:1902589 single-organism organelle organization; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:0050789 regulation of biological process; GO:0032940 secretion by cell; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0001775 cell activation; GO:0043299 leukocyte degranulation; GO:0051179 localization; GO:0006955 immune response; GO:0006887 exocytosis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0016020 membrane; GO:1904724 tertiary granule lumen; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005911 cell-cell junction; GO:0005623 cell; GO:0032432 actin filament bundle; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005856 cytoskeleton; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0005925 focal adhesion; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0001725 stress fiber; GO:0030055 cell-substrate junction; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0042641 actomyosin; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0070820 tertiary granule; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0012505 endomembrane system; GO:0097517 contractile actin filament bundle; GO:0015629 actin cytoskeleton; GO:0005576 extracellular region; GO:0043226 organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0035580 specific granule lumen; GO:0042581 specific granule; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0003779 actin binding; GO:0050839 cell adhesion molecule binding; GO:0005515 protein binding; GO:0008092 cytoskeletal protein binding; GO:0005516 calmodulin binding; GO:0005488 binding; GO:0045296 cadherin binding; ",{"$nulls":3},"IPR001715; ","Calponin homology domain; \r"]
["Q99442","Translocation protein SEC62 OS=Homo sapiens OX=9606 GN=SEC62","SEC62",45.861,7.7058,7.3,3,3,3,1.09,1.025,1.012,0.945,0.948,0.994,0.923,0.0475,"plasma membrane\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0046907 intracellular transport; GO:0033554 cellular response to stress; GO:0072594 establishment of protein localization to organelle; GO:0034976 response to endoplasmic reticulum stress; GO:0035967 cellular response to topologically incorrect protein; GO:0071310 cellular response to organic substance; GO:0044699 single-organism process; GO:0036498 IRE1-mediated unfolded protein response; GO:0006613 cotranslational protein targeting to membrane; GO:0050896 response to stimulus; GO:0015031 protein transport; GO:0030968 endoplasmic reticulum unfolded protein response; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0035966 response to topologically incorrect protein; GO:0007154 cell communication; GO:0070972 protein localization to endoplasmic reticulum; GO:0006886 intracellular protein transport; GO:0033365 protein localization to organelle; GO:0034613 cellular protein localization; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0090150 establishment of protein localization to membrane; GO:0009987 cellular process; GO:0070887 cellular response to chemical stimulus; GO:0006986 response to unfolded protein; GO:0051716 cellular response to stimulus; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0034620 cellular response to unfolded protein; GO:0006950 response to stress; GO:0072657 protein localization to membrane; GO:0045047 protein targeting to ER; GO:0071702 organic substance transport; GO:0010033 response to organic substance; GO:0023052 signaling; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:0070727 cellular macromolecule localization; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0006620 posttranslational protein targeting to membrane; GO:0051179 localization; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0005791 rough endoplasmic reticulum; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044432 endoplasmic reticulum part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; ","GO:0022892 substrate-specific transporter activity; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0008565 protein transporter activity; GO:0005215 transporter activity; ","K12275","SEC62; translocation protein SEC62","hsa03060 Protein export - Homo sapiens (human); hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); ","IPR011991; ","Winged helix-turn-helix DNA-binding domain; \r"]
["Q99460","26S proteasome non-ATPase regulatory subunit 1 OS=Homo sapiens OX=9606 GN=PSMD1","PSMD1",105.84,175.74,28.3,23,35,23,0.937,0.926,0.993,1.026,1.058,1.069,1.104,0.0162,"cytoplasm\r","GO:0044700 single organism signaling; GO:0010608 posttranscriptional regulation of gene expression; GO:0051443 positive regulation of ubiquitin-protein transferase activity; GO:0031347 regulation of defense response; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:1903364 positive regulation of cellular protein catabolic process; GO:0008152 metabolic process; GO:0090263 positive regulation of canonical Wnt signaling pathway; GO:0044093 positive regulation of molecular function; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0016055 Wnt signaling pathway; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0006521 regulation of cellular amino acid metabolic process; GO:0080090 regulation of primary metabolic process; GO:0010972 negative regulation of G2/M transition of mitotic cell cycle; GO:0044763 single-organism cellular process; GO:0060828 regulation of canonical Wnt signaling pathway; GO:0043086 negative regulation of catalytic activity; GO:0033209 tumor necrosis factor-mediated signaling pathway; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0000165 MAPK cascade; GO:1901575 organic substance catabolic process; GO:0007267 cell-cell signaling; GO:0002223 stimulatory C-type lectin receptor signaling pathway; GO:0030163 protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0060071 Wnt signaling pathway, planar cell polarity pathway; GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0016310 phosphorylation; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0000209 protein polyubiquitination; GO:0043487 regulation of RNA stability; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0009889 regulation of biosynthetic process; GO:0009896 positive regulation of catabolic process; GO:0043620 regulation of DNA-templated transcription in response to stress; GO:0070482 response to oxygen levels; GO:0044248 cellular catabolic process; GO:0042176 regulation of protein catabolic process; GO:0038093 Fc receptor signaling pathway; GO:0050778 positive regulation of immune response; GO:0023014 signal transduction by protein phosphorylation; GO:0016567 protein ubiquitination; GO:0006950 response to stress; GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0002263 cell activation involved in immune response; GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress; GO:1903321 negative regulation of protein modification by small protein conjugation or removal; GO:0045055 regulated exocytosis; GO:0032446 protein modification by small protein conjugation; GO:0031398 positive regulation of protein ubiquitination; GO:0031325 positive regulation of cellular metabolic process; GO:0030177 positive regulation of Wnt signaling pathway; GO:1904668 positive regulation of ubiquitin protein ligase activity; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0043412 macromolecule modification; GO:0006955 immune response; GO:0070646 protein modification by small protein removal; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0031331 positive regulation of cellular catabolic process; GO:0044699 single-organism process; GO:0031400 negative regulation of protein modification process; GO:0006796 phosphate-containing compound metabolic process; GO:0031396 regulation of protein ubiquitination; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0045930 negative regulation of mitotic cell cycle; GO:0009893 positive regulation of metabolic process; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0034612 response to tumor necrosis factor; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0051726 regulation of cell cycle; GO:0034097 response to cytokine; GO:0031326 regulation of cellular biosynthetic process; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0198738 cell-cell signaling by wnt; GO:0010565 regulation of cellular ketone metabolic process; GO:0032940 secretion by cell; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0036211 protein modification process; GO:0090175 regulation of establishment of planar polarity; GO:0045786 negative regulation of cell cycle; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:1901988 negative regulation of cell cycle phase transition; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0010498 proteasomal protein catabolic process; GO:0071704 organic substance metabolic process; GO:0045862 positive regulation of proteolysis; GO:2000027 regulation of organ morphogenesis; GO:0006468 protein phosphorylation; GO:0023056 positive regulation of signaling; GO:0001666 response to hypoxia; GO:0002757 immune response-activating signal transduction; GO:0010647 positive regulation of cell communication; GO:0071453 cellular response to oxygen levels; GO:0019221 cytokine-mediated signaling pathway; GO:0031397 negative regulation of protein ubiquitination; GO:0006355 regulation of transcription, DNA-templated; GO:0035556 intracellular signal transduction; GO:0019941 modification-dependent protein catabolic process; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia; GO:1902749 regulation of cell cycle G2/M phase transition; GO:0043488 regulation of mRNA stability; GO:0043085 positive regulation of catalytic activity; GO:0002366 leukocyte activation involved in immune response; GO:0019882 antigen processing and presentation; GO:0042119 neutrophil activation; GO:0050852 T cell receptor signaling pathway; GO:0002684 positive regulation of immune system process; GO:0038095 Fc-epsilon receptor signaling pathway; GO:0051248 negative regulation of protein metabolic process; GO:0022402 cell cycle process; GO:1902750 negative regulation of cell cycle G2/M phase transition; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0045321 leukocyte activation; GO:0002220 innate immune response activating cell surface receptor signaling pathway; GO:0007166 cell surface receptor signaling pathway; GO:0071345 cellular response to cytokine stimulus; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0051347 positive regulation of transferase activity; GO:1903362 regulation of cellular protein catabolic process; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0002443 leukocyte mediated immunity; GO:0002758 innate immune response-activating signal transduction; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0031323 regulation of cellular metabolic process; GO:2000058 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0010948 negative regulation of cell cycle process; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0002682 regulation of immune system process; GO:0031145 anaphase-promoting complex-dependent catabolic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0007346 regulation of mitotic cell cycle; GO:0002283 neutrophil activation involved in immune response; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:0051239 regulation of multicellular organismal process; GO:0031349 positive regulation of defense response; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:1901987 regulation of cell cycle phase transition; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0010389 regulation of G2/M transition of mitotic cell cycle; GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; GO:0009966 regulation of signal transduction; GO:0038061 NIK/NF-kappaB signaling; GO:0071456 cellular response to hypoxia; GO:0002253 activation of immune response; GO:0016192 vesicle-mediated transport; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1904666 regulation of ubiquitin protein ligase activity; GO:0055085 transmembrane transport; GO:0051247 positive regulation of protein metabolic process; GO:0051438 regulation of ubiquitin-protein transferase activity; GO:0030111 regulation of Wnt signaling pathway; GO:0006793 phosphorus metabolic process; GO:0001775 cell activation; GO:0036293 response to decreased oxygen levels; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:0050793 regulation of developmental process; GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process; GO:0006887 exocytosis; GO:0051444 negative regulation of ubiquitin-protein transferase activity; GO:0090090 negative regulation of canonical Wnt signaling pathway; GO:0051234 establishment of localization; GO:0035567 non-canonical Wnt signaling pathway; GO:1905330 regulation of morphogenesis of an epithelium; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:1901991 negative regulation of mitotic cell cycle phase transition; GO:0045088 regulation of innate immune response; GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I; GO:0070887 cellular response to chemical stimulus; GO:0002274 myeloid leukocyte activation; GO:0050851 antigen receptor-mediated signaling pathway; GO:0010468 regulation of gene expression; GO:0030178 negative regulation of Wnt signaling pathway; GO:0048002 antigen processing and presentation of peptide antigen; GO:0002446 neutrophil mediated immunity; GO:0048522 positive regulation of cellular process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0051348 negative regulation of transferase activity; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0019222 regulation of metabolic process; GO:0043299 leukocyte degranulation; GO:2000026 regulation of multicellular organismal development; GO:0002218 activation of innate immune response; GO:1904667 negative regulation of ubiquitin protein ligase activity; GO:0002252 immune effector process; GO:0071356 cellular response to tumor necrosis factor; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0016579 protein deubiquitination; GO:1903322 positive regulation of protein modification by small protein conjugation or removal; GO:0006508 proteolysis; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:0033238 regulation of cellular amine metabolic process; GO:0043632 modification-dependent macromolecule catabolic process; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0045089 positive regulation of innate immune response; GO:0031401 positive regulation of protein modification process; GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0051246 regulation of protein metabolic process; GO:0009057 macromolecule catabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0045732 positive regulation of protein catabolic process; GO:0009967 positive regulation of signal transduction; GO:0036294 cellular response to decreased oxygen levels; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005838 proteasome regulatory particle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:1905369 endopeptidase complex; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0031983 vesicle lumen; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0022624 proteasome accessory complex; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:1905368 peptidase complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0000502 proteasome complex; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0042582 azurophil granule; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0030234 enzyme regulator activity; GO:0098772 molecular function regulator; GO:0005488 binding; ","K03032","PSMD1; 26S proteasome regulatory subunit N2","hsa03050 Proteasome - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); ","IPR011989; IPR016024; ","Armadillo-like helical; Armadillo-type fold; \r"]
["Q99470","Stromal cell-derived factor 2 OS=Homo sapiens OX=9606 GN=SDF2","SDF2",23.026,2.4609,6.6,2,2,2,1.053,0.945,1.005,0.975,1.033,0.996,1,0.978,"extracellular\r","GO:0033554 cellular response to stress; GO:0043413 macromolecule glycosylation; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0034976 response to endoplasmic reticulum stress; GO:0035967 cellular response to topologically incorrect protein; GO:0071310 cellular response to organic substance; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0036503 ERAD pathway; GO:0009058 biosynthetic process; GO:0050896 response to stimulus; GO:0071218 cellular response to misfolded protein; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0071712 ER-associated misfolded protein catabolic process; GO:0008152 metabolic process; GO:0035966 response to topologically incorrect protein; GO:1901137 carbohydrate derivative biosynthetic process; GO:0035268 protein mannosylation; GO:0044248 cellular catabolic process; GO:0035269 protein O-linked mannosylation; GO:1901135 carbohydrate derivative metabolic process; GO:0006508 proteolysis; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0006515 misfolded or incompletely synthesized protein catabolic process; GO:0009987 cellular process; GO:0070887 cellular response to chemical stimulus; GO:0070085 glycosylation; GO:0097502 mannosylation; GO:0051716 cellular response to stimulus; GO:0006486 protein glycosylation; GO:0044265 cellular macromolecule catabolic process; GO:0009101 glycoprotein biosynthetic process; GO:0006950 response to stress; GO:0051788 response to misfolded protein; GO:0044712 single-organism catabolic process; GO:0044763 single-organism cellular process; GO:0009100 glycoprotein metabolic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:1901575 organic substance catabolic process; GO:0042221 response to chemical; GO:0034645 cellular macromolecule biosynthetic process; GO:0030163 protein catabolic process; GO:0044710 single-organism metabolic process; GO:0009057 macromolecule catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0006493 protein O-linked glycosylation; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:0009056 catabolic process; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044432 endoplasmic reticulum part; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; ","GO:0016757 transferase activity, transferring glycosyl groups; GO:0016758 transferase activity, transferring hexosyl groups; GO:0000030 mannosyltransferase activity; GO:0003824 catalytic activity; GO:0016740 transferase activity; GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity; ",{"$nulls":3},"IPR016093; ","MIR motif; \r"]
["Q99538","Legumain OS=Homo sapiens OX=9606 GN=LGMN","LGMN",49.411,47.535,11.3,4,6,4,0.965,0.941,0.961,1,1.066,1.068,1.093,0.0182,"extracellular\r","GO:0044700 single organism signaling; GO:0051093 negative regulation of developmental process; GO:0010941 regulation of cell death; GO:0009968 negative regulation of signal transduction; GO:0048640 negative regulation of developmental growth; GO:1901185 negative regulation of ERBB signaling pathway; GO:0023051 regulation of signaling; GO:0043523 regulation of neuron apoptotic process; GO:0044699 single-organism process; GO:0051241 negative regulation of multicellular organismal process; GO:0016485 protein processing; GO:0031347 regulation of defense response; GO:0044237 cellular metabolic process; GO:0006775 fat-soluble vitamin metabolic process; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0045088 regulation of innate immune response; GO:0002221 pattern recognition receptor signaling pathway; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0006629 lipid metabolic process; GO:0051716 cellular response to stimulus; GO:0045926 negative regulation of growth; GO:0040014 regulation of multicellular organism growth; GO:0043112 receptor metabolic process; GO:0002758 innate immune response-activating signal transduction; GO:0044281 small molecule metabolic process; GO:0048002 antigen processing and presentation of peptide antigen; GO:0008202 steroid metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0023052 signaling; GO:0002764 immune response-regulating signaling pathway; GO:0002495 antigen processing and presentation of peptide antigen via MHC class II; GO:0032501 multicellular organismal process; GO:0050776 regulation of immune response; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0032801 receptor catabolic process; GO:1901575 organic substance catabolic process; GO:0050789 regulation of biological process; GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; GO:0044710 single-organism metabolic process; GO:0002224 toll-like receptor signaling pathway; GO:0030163 protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0002682 regulation of immune system process; GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II; GO:0060548 negative regulation of cell death; GO:0050794 regulation of cellular process; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0040008 regulation of growth; GO:0043069 negative regulation of programmed cell death; GO:0002218 activation of innate immune response; GO:1901615 organic hydroxy compound metabolic process; GO:0009628 response to abiotic stimulus; GO:0044267 cellular protein metabolic process; GO:0043067 regulation of programmed cell death; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0080134 regulation of response to stress; GO:0048638 regulation of developmental growth; GO:0050896 response to stimulus; GO:0040015 negative regulation of multicellular organism growth; GO:0051239 regulation of multicellular organismal process; GO:0071704 organic substance metabolic process; GO:0006766 vitamin metabolic process; GO:0009268 response to pH; GO:0031349 positive regulation of defense response; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0043524 negative regulation of neuron apoptotic process; GO:1901184 regulation of ERBB signaling pathway; GO:0043066 negative regulation of apoptotic process; GO:0002757 immune response-activating signal transduction; GO:0044248 cellular catabolic process; GO:0006508 proteolysis; GO:0006624 vacuolar protein processing; GO:0050778 positive regulation of immune response; GO:0009987 cellular process; GO:0009966 regulation of signal transduction; GO:0042359 vitamin D metabolic process; GO:1901214 regulation of neuron death; GO:1901215 negative regulation of neuron death; GO:0002253 activation of immune response; GO:0044265 cellular macromolecule catabolic process; GO:0045089 positive regulation of innate immune response; GO:0003008 system process; GO:0003014 renal system process; GO:0002376 immune system process; GO:0048585 negative regulation of response to stimulus; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0019882 antigen processing and presentation; GO:0002684 positive regulation of immune system process; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0010447 response to acidic pH; GO:0051604 protein maturation; GO:0048584 positive regulation of response to stimulus; GO:0009056 catabolic process; GO:0050793 regulation of developmental process; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0036021 endolysosome lumen; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0036019 endolysosome; GO:0005623 cell; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0045177 apical part of cell; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0005770 late endosome; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0005576 extracellular region; GO:0043202 lysosomal lumen; GO:0031904 endosome lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0004175 endopeptidase activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0008234 cysteine-type peptidase activity; GO:0008233 peptidase activity; GO:0016787 hydrolase activity; GO:0004197 cysteine-type endopeptidase activity; GO:0003824 catalytic activity; ","K01369","LGMN; legumain [EC:3.4.22.34]","hsa04142 Lysosome - Homo sapiens (human); hsa04612 Antigen processing and presentation - Homo sapiens (human); "]
["Q99584","Protein S100-A13 OS=Homo sapiens OX=9606 GN=S100A13","S100A13",11.471,30.795,49,6,14,6,1.227,1.182,1.194,0.777,0.811,0.778,0.657,1.98E-5,"cytoplasm\r","GO:0002279 mast cell activation involved in immune response; GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0045576 mast cell activation; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0010646 regulation of cell communication; GO:0051649 establishment of localization in cell; GO:0008360 regulation of cell shape; GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling; GO:0009306 protein secretion; GO:0010035 response to inorganic substance; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0002443 leukocyte mediated immunity; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0032501 multicellular organismal process; GO:0010038 response to metal ion; GO:1902582 single-organism intracellular transport; GO:0002444 myeloid leukocyte mediated immunity; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0046688 response to copper ion; GO:0032940 secretion by cell; GO:0048583 regulation of response to stimulus; GO:0050703 interleukin-1 alpha secretion; GO:0043299 leukocyte degranulation; GO:0050701 interleukin-1 secretion; GO:0051640 organelle localization; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0046907 intracellular transport; GO:0042127 regulation of cell proliferation; GO:0002252 immune effector process; GO:0009628 response to abiotic stimulus; GO:0043303 mast cell degranulation; GO:0050896 response to stimulus; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0023056 positive regulation of signaling; GO:0002448 mast cell mediated immunity; GO:1902580 single-organism cellular localization; GO:0010647 positive regulation of cell communication; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:0032418 lysosome localization; GO:0050663 cytokine secretion; GO:0032612 interleukin-1 production; GO:1902531 regulation of intracellular signal transduction; GO:0016192 vesicle-mediated transport; GO:0051602 response to electrical stimulus; GO:0032610 interleukin-1 alpha production; GO:0071702 organic substance transport; GO:0002376 immune system process; GO:0051656 establishment of organelle localization; GO:0048518 positive regulation of biological process; GO:0002263 cell activation involved in immune response; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0002366 leukocyte activation involved in immune response; GO:0045055 regulated exocytosis; GO:0001816 cytokine production; GO:0022603 regulation of anatomical structure morphogenesis; GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling; GO:0001775 cell activation; GO:0009967 positive regulation of signal transduction; GO:0051128 regulation of cellular component organization; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0006955 immune response; GO:0050793 regulation of developmental process; GO:0022604 regulation of cell morphogenesis; GO:0008284 positive regulation of cell proliferation; GO:0006887 exocytosis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0005764 lysosome; GO:0042629 mast cell granule; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005773 vacuole; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0019838 growth factor binding; GO:0005102 receptor binding; GO:0046983 protein dimerization activity; GO:0043167 ion binding; GO:0005515 protein binding; GO:0005507 copper ion binding; GO:0008270 zinc ion binding; GO:0050786 RAGE receptor binding; GO:0042802 identical protein binding; GO:0046914 transition metal ion binding; GO:0005488 binding; GO:0042803 protein homodimerization activity; GO:0008289 lipid binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005509 calcium ion binding; GO:0017134 fibroblast growth factor binding; ",{"$nulls":3},"IPR011992; IPR013787; ","\"EF-hand domain pair; S100/CaBP-9k-type, calcium binding, subdomain; \"\r"]
["Q99614","Tetratricopeptide repeat protein 1 OS=Homo sapiens OX=9606 GN=TTC1","TTC1",33.526,5.8349,9.6,3,4,3,0.92,0.955,0.912,1.075,1.041,1.097,1.153,0.0024,"cytoplasm\r","GO:0006457 protein folding; GO:0009987 cellular process; ","GO:0031903 microbody membrane; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0098588 bounding membrane of organelle; GO:0044439 peroxisomal part; GO:0031090 organelle membrane; GO:0005777 peroxisome; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0044438 microbody part; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0005778 peroxisomal membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005622 intracellular; GO:0044464 cell part; GO:0042579 microbody; GO:0098805 whole membrane; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0051082 unfolded protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR011990; IPR013026; ","Tetratricopeptide-like helical domain; Tetratricopeptide repeat-containing domain; \r"]
["Q99615","DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7","DNAJC7",56.44,6.7703,5.5,3,4,3,0.922,0.913,1.01,1.085,1.004,1.066,1.109,0.0594,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0061077 chaperone-mediated protein folding; GO:0080134 regulation of response to stress; GO:0043085 positive regulation of catalytic activity; GO:0006457 protein folding; GO:0070389 chaperone cofactor-dependent protein refolding; GO:0050789 regulation of biological process; GO:0080135 regulation of cellular response to stress; GO:0051336 regulation of hydrolase activity; GO:0051345 positive regulation of hydrolase activity; GO:0043462 regulation of ATPase activity; GO:0050790 regulation of catalytic activity; GO:0044093 positive regulation of molecular function; GO:0048583 regulation of response to stimulus; GO:0065009 regulation of molecular function; GO:1900034 regulation of cellular response to heat; GO:0032781 positive regulation of ATPase activity; GO:0009987 cellular process; GO:0042026 protein refolding; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005856 cytoskeleton; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0001671 ATPase activator activity; GO:0031072 heat shock protein binding; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0005515 protein binding; GO:0060590 ATPase regulator activity; GO:0098772 molecular function regulator; GO:0008047 enzyme activator activity; ","K09527",null,null,"IPR011990; IPR001623; IPR013026; ","Tetratricopeptide-like helical domain; DnaJ domain; Tetratricopeptide repeat-containing domain; \r"]
["Q99685","Monoglyceride lipase OS=Homo sapiens OX=9606 GN=MGLL","MGLL",33.261,19.535,16.2,4,9,4,1.263,1.103,1.332,0.844,0.749,0.743,0.632,0.00277,"cytoplasm\r","GO:0036155 acylglycerol acyl-chain remodeling; GO:0046486 glycerolipid metabolic process; GO:0016053 organic acid biosynthetic process; GO:0023051 regulation of signaling; GO:1901568 fatty acid derivative metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044255 cellular lipid metabolic process; GO:0031347 regulation of defense response; GO:0044237 cellular metabolic process; GO:0008610 lipid biosynthetic process; GO:0046461 neutral lipid catabolic process; GO:0008152 metabolic process; GO:0010646 regulation of cell communication; GO:0006639 acylglycerol metabolic process; GO:0031644 regulation of neurological system process; GO:0044057 regulation of system process; GO:0032787 monocarboxylic acid metabolic process; GO:0006690 icosanoid metabolic process; GO:0006629 lipid metabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0008277 regulation of G-protein coupled receptor protein signaling pathway; GO:0006633 fatty acid biosynthetic process; GO:1901575 organic substance catabolic process; GO:0046394 carboxylic acid biosynthetic process; GO:0050789 regulation of biological process; GO:0044710 single-organism metabolic process; GO:0006954 inflammatory response; GO:0048583 regulation of response to stimulus; GO:0006952 defense response; GO:0006082 organic acid metabolic process; GO:0043436 oxoacid metabolic process; GO:0046503 glycerolipid catabolic process; GO:0033559 unsaturated fatty acid metabolic process; GO:0050794 regulation of cellular process; GO:0019369 arachidonic acid metabolic process; GO:0080134 regulation of response to stress; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:0046464 acylglycerol catabolic process; GO:0071704 organic substance metabolic process; GO:2000124 regulation of endocannabinoid signaling pathway; GO:0044248 cellular catabolic process; GO:0051930 regulation of sensory perception of pain; GO:0009987 cellular process; GO:0009966 regulation of signal transduction; GO:0019433 triglyceride catabolic process; GO:0006638 neutral lipid metabolic process; GO:0016042 lipid catabolic process; GO:0044711 single-organism biosynthetic process; GO:0006950 response to stress; GO:0051931 regulation of sensory perception; GO:0044712 single-organism catabolic process; GO:0032101 regulation of response to external stimulus; GO:0006631 fatty acid metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0006641 triglyceride metabolic process; GO:0001676 long-chain fatty acid metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0044283 small molecule biosynthetic process; GO:0050727 regulation of inflammatory response; GO:0044242 cellular lipid catabolic process; GO:0009056 catabolic process; GO:0072330 monocarboxylic acid biosynthetic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0019898 extrinsic component of membrane; GO:0071944 cell periphery; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0005886 plasma membrane; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044432 endoplasmic reticulum part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0042802 identical protein binding; GO:0052689 carboxylic ester hydrolase activity; GO:0003824 catalytic activity; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0046983 protein dimerization activity; GO:0016788 hydrolase activity, acting on ester bonds; GO:0004622 lysophospholipase activity; GO:0004620 phospholipase activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0016298 lipase activity; GO:0047372 acylglycerol lipase activity; ","K01054","MGLL; acylglycerol lipase [EC:3.1.1.23]","hsa04923 Regulation of lipolysis in adipocytes - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00561 Glycerolipid metabolism - Homo sapiens (human); ","IPR029058; IPR000073; IPR022742; ","\"Alpha/Beta hydrolase fold; Alpha/beta hydrolase fold-1; Serine aminopeptidase, S33; \"\r"]
["Q99707","Methionine synthase OS=Homo sapiens OX=9606 GN=MTR","MTR",140.53,11.406,2.6,2,3,2,0.971,1.123,1.157,0.967,0.96,0.841,0.851,0.0862,"cytoplasm\r","GO:0000097 sulfur amino acid biosynthetic process; GO:0016053 organic acid biosynthetic process; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0044272 sulfur compound biosynthetic process; GO:0000096 sulfur amino acid metabolic process; GO:0032259 methylation; GO:0009611 response to wounding; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:1901607 alpha-amino acid biosynthetic process; GO:0006979 response to oxidative stress; GO:0006555 methionine metabolic process; GO:0010035 response to inorganic substance; GO:0034599 cellular response to oxidative stress; GO:0070887 cellular response to chemical stimulus; GO:0009235 cobalamin metabolic process; GO:0006790 sulfur compound metabolic process; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0034614 cellular response to reactive oxygen species; GO:0048699 generation of neurons; GO:0000302 response to reactive oxygen species; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0031102 neuron projection regeneration; GO:0032501 multicellular organismal process; GO:0071732 cellular response to nitric oxide; GO:0071731 response to nitric oxide; GO:0046394 carboxylic acid biosynthetic process; GO:0042221 response to chemical; GO:0030030 cell projection organization; GO:1901699 cellular response to nitrogen compound; GO:0044710 single-organism metabolic process; GO:0033013 tetrapyrrole metabolic process; GO:1901698 response to nitrogen compound; GO:0071241 cellular response to inorganic substance; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:0043436 oxoacid metabolic process; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0033554 cellular response to stress; GO:0006725 cellular aromatic compound metabolic process; GO:0009066 aspartate family amino acid metabolic process; GO:1901700 response to oxygen-containing compound; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0071704 organic substance metabolic process; GO:0009086 methionine biosynthetic process; GO:0031103 axon regeneration; GO:0006766 vitamin metabolic process; GO:0030154 cell differentiation; GO:0046483 heterocycle metabolic process; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0006767 water-soluble vitamin metabolic process; GO:0008652 cellular amino acid biosynthetic process; GO:0009067 aspartate family amino acid biosynthetic process; GO:0044711 single-organism biosynthetic process; GO:0006950 response to stress; GO:0048731 system development; GO:0006807 nitrogen compound metabolic process; GO:0031175 neuron projection development; GO:0044238 primary metabolic process; GO:1901605 alpha-amino acid metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0042558 pteridine-containing compound metabolic process; GO:0061564 axon development; GO:0030182 neuron differentiation; GO:0048678 response to axon injury; GO:1901701 cellular response to oxygen-containing compound; GO:0044767 single-organism developmental process; GO:1902170 cellular response to reactive nitrogen species; GO:0019752 carboxylic acid metabolic process; GO:0044283 small molecule biosynthetic process; GO:0031099 regeneration; GO:0071840 cellular component organization or biogenesis; GO:1901564 organonitrogen compound metabolic process; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0044444 cytoplasmic part; ","GO:0008757 S-adenosylmethionine-dependent methyltransferase activity; GO:0019842 vitamin binding; GO:0008168 methyltransferase activity; GO:0043167 ion binding; GO:0042084 5-methyltetrahydrofolate-dependent methyltransferase activity; GO:0016741 transferase activity, transferring one-carbon groups; GO:0005515 protein binding; GO:0008705 methionine synthase activity; GO:0031419 cobalamin binding; GO:0008270 zinc ion binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0008172 S-methyltransferase activity; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0016740 transferase activity; GO:0046906 tetrapyrrole binding; GO:0036094 small molecule binding; ","K00548","metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]","hsa00670 One carbon pool by folate - Homo sapiens (human); hsa00450 Selenocompound metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00270 Cysteine and methionine metabolism - Homo sapiens (human); hsa01230 Biosynthesis of amino acids - Homo sapiens (human); ","IPR004223; IPR011005; IPR033706; IPR003759; IPR003726; IPR000489; IPR006158; ","\"Vitamin B12-dependent methionine synthase, activation domain; Dihydropteroate synthase-like; Methionine synthase, B12-binding domain; Cobalamin (vitamin B12)-binding module, cap domain; Homocysteine-binding domain; Pterin-binding domain; Cobalamin (vitamin B12)-binding domain; \"\r"]
["Q99733","Nucleosome assembly protein 1-like 4 OS=Homo sapiens OX=9606 GN=NAP1L4","NAP1L4",42.823,38.16,19.2,7,9,6,0.986,0.952,1.028,1.08,0.937,1.025,1.026,0.636,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0016043 cellular component organization; GO:0034728 nucleosome organization; GO:0034622 cellular macromolecular complex assembly; GO:0006333 chromatin assembly or disassembly; GO:0043933 macromolecular complex subunit organization; GO:0065004 protein-DNA complex assembly; GO:0006323 DNA packaging; GO:0006334 nucleosome assembly; GO:0051276 chromosome organization; GO:0022607 cellular component assembly; GO:0006996 organelle organization; GO:0065003 macromolecular complex assembly; GO:0006325 chromatin organization; GO:0031497 chromatin assembly; GO:0009987 cellular process; GO:0071824 protein-DNA complex subunit organization; GO:0071840 cellular component organization or biogenesis; GO:0071103 DNA conformation change; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005515 protein binding; GO:0051082 unfolded protein binding; GO:0005488 binding; GO:0003676 nucleic acid binding; ","K11282"]
["Q99747","Gamma-soluble NSF attachment protein OS=Homo sapiens OX=9606 GN=NAPG","NAPG",34.746,8.6613,12.2,4,5,4,1.015,0.912,0.955,1.033,1.108,0.987,1.085,0.148,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0065008 regulation of biological quality; GO:0048193 Golgi vesicle transport; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0051649 establishment of localization in cell; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0006886 intracellular protein transport; GO:0034613 cellular protein localization; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0071822 protein complex subunit organization; GO:0006891 intra-Golgi vesicle-mediated transport; GO:0016192 vesicle-mediated transport; GO:0061025 membrane fusion; GO:0071702 organic substance transport; GO:0051641 cellular localization; GO:0043933 macromolecular complex subunit organization; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:0070727 cellular macromolecule localization; GO:0061024 membrane organization; GO:0031647 regulation of protein stability; GO:0051179 localization; GO:0070271 protein complex biogenesis; GO:0050821 protein stabilization; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0005765 lysosomal membrane; GO:0044425 membrane part; GO:0043209 myelin sheath; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0031201 SNARE complex; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0000149 SNARE binding; GO:0005515 protein binding; GO:0005483 soluble NSF attachment protein activity; GO:0019905 syntaxin binding; GO:0005488 binding; ","K21198",null,null,"IPR011990; ","Tetratricopeptide-like helical domain; \r"]
["Q99798","Aconitate hydratase, mitochondrial OS=Homo sapiens OX=9606 GN=ACO2","ACO2",85.424,323.31,49.4,29,57,29,1.034,1.01,1.094,0.939,0.963,0.946,0.908,0.0178,"mitochondria\r","GO:0044707 single-multicellular organism process; GO:0048732 gland development; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0061008 hepaticobiliary system development; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0032502 developmental process; GO:0072350 tricarboxylic acid metabolic process; GO:0006950 response to stress; GO:0048731 system development; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006099 tricarboxylic acid cycle; GO:0006102 isocitrate metabolic process; GO:0044238 primary metabolic process; GO:0045333 cellular respiration; GO:0032501 multicellular organismal process; GO:0006101 citrate metabolic process; GO:0048513 animal organ development; GO:0001889 liver development; GO:0009060 aerobic respiration; GO:0044710 single-organism metabolic process; GO:0044767 single-organism developmental process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0019752 carboxylic acid metabolic process; GO:0035900 response to isolation stress; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:0043436 oxoacid metabolic process; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0070013 intracellular organelle lumen; GO:0043209 myelin sheath; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0005506 iron ion binding; GO:0043167 ion binding; GO:0003994 aconitate hydratase activity; GO:0016829 lyase activity; GO:0016836 hydro-lyase activity; GO:0051539 4 iron, 4 sulfur cluster binding; GO:0016835 carbon-oxygen lyase activity; GO:0051538 3 iron, 4 sulfur cluster binding; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0051536 iron-sulfur cluster binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0051540 metal cluster binding; ","K01681","ACO; aconitate hydratase [EC:4.2.1.3]","hsa01210 2-Oxocarboxylic acid metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00020 Citrate cycle (TCA cycle) - Homo sapiens (human); hsa01230 Biosynthesis of amino acids - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); hsa00630 Glyoxylate and dicarboxylate metabolism - Homo sapiens (human); ","IPR001030; IPR000573; IPR015932; IPR015928; IPR015931; ","\"Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain; Aconitase A/isopropylmalate dehydratase small subunit, swivel domain; Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2; Aconitase/3-isopropylmalate dehydratase, swivel; Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3; \"\r"]
["Q99816","Tumor susceptibility gene 101 protein OS=Homo sapiens OX=9606 GN=TSG101","TSG101",43.944,21.208,13.1,4,4,4,0.994,0.972,1.123,0.932,0.957,1.028,0.944,0.354,"cytoplasm\r","GO:0060627 regulation of vesicle-mediated transport; GO:0044085 cellular component biogenesis; GO:1901185 negative regulation of ERBB signaling pathway; GO:0006914 autophagy; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0008285 negative regulation of cell proliferation; GO:0001558 regulation of cell growth; GO:0009913 epidermal cell differentiation; GO:1902583 multi-organism intracellular transport; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0008152 metabolic process; GO:0032879 regulation of localization; GO:0036258 multivesicular body assembly; GO:0008544 epidermis development; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0075733 intracellular transport of virus; GO:0008104 protein localization; GO:0044419 interspecies interaction between organisms; GO:0046903 secretion; GO:0044765 single-organism transport; GO:1903543 positive regulation of exosomal secretion; GO:0042325 regulation of phosphorylation; GO:0043588 skin development; GO:0051174 regulation of phosphorus metabolic process; GO:0045921 positive regulation of exocytosis; GO:0080090 regulation of primary metabolic process; GO:0039702 viral budding via host ESCRT complex; GO:0044763 single-organism cellular process; GO:1903772 regulation of viral budding via host ESCRT complex; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0008333 endosome to lysosome transport; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0030163 protein catabolic process; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0051223 regulation of protein transport; GO:0006464 cellular protein modification process; GO:0051301 cell division; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0030855 epithelial cell differentiation; GO:0051047 positive regulation of secretion; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0046907 intracellular transport; GO:0042127 regulation of cell proliferation; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0017157 regulation of exocytosis; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:1903541 regulation of exosomal secretion; GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway; GO:0045892 negative regulation of transcription, DNA-templated; GO:0023057 negative regulation of signaling; GO:1902578 single-organism localization; GO:0010648 negative regulation of cell communication; GO:0009889 regulation of biosynthetic process; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0044248 cellular catabolic process; GO:0032880 regulation of protein localization; GO:0007275 multicellular organism development; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0009966 regulation of signal transduction; GO:0030100 regulation of endocytosis; GO:1902531 regulation of intracellular signal transduction; GO:0016567 protein ubiquitination; GO:0046794 transport of virus; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0043900 regulation of multi-organism process; GO:1902188 positive regulation of viral release from host cell; GO:0048284 organelle fusion; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0044766 multi-organism transport; GO:0045184 establishment of protein localization; GO:1902186 regulation of viral release from host cell; GO:0009890 negative regulation of biosynthetic process; GO:1904951 positive regulation of establishment of protein localization; GO:0032446 protein modification by small protein conjugation; GO:0097576 vacuole fusion; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0006900 membrane budding; GO:0043412 macromolecule modification; GO:0051179 localization; GO:0006887 exocytosis; GO:0010256 endomembrane system organization; GO:0009968 negative regulation of signal transduction; GO:0040017 positive regulation of locomotion; GO:0023051 regulation of signaling; GO:0048869 cellular developmental process; GO:0051046 regulation of secretion; GO:0044699 single-organism process; GO:1902581 multi-organism cellular localization; GO:0044764 multi-organism cellular process; GO:0097734 extracellular exosome biogenesis; GO:1902115 regulation of organelle assembly; GO:0051253 negative regulation of RNA metabolic process; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:2001141 regulation of RNA biosynthetic process; GO:0010646 regulation of cell communication; GO:0051649 establishment of localization in cell; GO:0022607 cellular component assembly; GO:0007033 vacuole organization; GO:0033036 macromolecule localization; GO:0051726 regulation of cell cycle; GO:0016236 macroautophagy; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0032502 developmental process; GO:0060429 epithelium development; GO:1903774 positive regulation of viral budding via host ESCRT complex; GO:1903902 positive regulation of viral life cycle; GO:0010468 regulation of gene expression; GO:0043902 positive regulation of multi-organism process; GO:0030216 keratinocyte differentiation; GO:0009888 tissue development; GO:0031326 regulation of cellular biosynthetic process; GO:0048522 positive regulation of cellular process; GO:0036257 multivesicular body organization; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:1903530 regulation of secretion by cell; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051050 positive regulation of transport; GO:0016197 endosomal transport; GO:1902589 single-organism organelle organization; GO:0006513 protein monoubiquitination; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0010638 positive regulation of organelle organization; GO:1903532 positive regulation of secretion by cell; GO:0032940 secretion by cell; GO:1902679 negative regulation of RNA biosynthetic process; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0051222 positive regulation of protein transport; GO:0043549 regulation of kinase activity; GO:0045859 regulation of protein kinase activity; GO:0016043 cellular component organization; GO:1902579 multi-organism localization; GO:0045786 negative regulation of cell cycle; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0040008 regulation of growth; GO:0044257 cellular protein catabolic process; GO:0019068 virion assembly; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0045807 positive regulation of endocytosis; GO:0043405 regulation of MAP kinase activity; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0097352 autophagosome maturation; GO:1902592 multi-organism membrane budding; GO:0044087 regulation of cellular component biogenesis; GO:0031324 negative regulation of cellular metabolic process; GO:0070201 regulation of establishment of protein localization; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0043408 regulation of MAPK cascade; GO:1901184 regulation of ERBB signaling pathway; GO:0070925 organelle assembly; GO:0016032 viral process; GO:0006508 proteolysis; GO:0009987 cellular process; GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; GO:0007041 lysosomal transport; GO:0043632 modification-dependent macromolecule catabolic process; GO:2000395 regulation of ubiquitin-dependent endocytosis; GO:0044265 cellular macromolecule catabolic process; GO:1903551 regulation of extracellular exosome assembly; GO:0006355 regulation of transcription, DNA-templated; GO:0044803 multi-organism membrane organization; GO:0010629 negative regulation of gene expression; GO:0019941 modification-dependent protein catabolic process; GO:0007050 cell cycle arrest; GO:0051049 regulation of transport; GO:0050792 regulation of viral process; GO:0001932 regulation of protein phosphorylation; GO:0033043 regulation of organelle organization; GO:0016050 vesicle organization; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0048585 negative regulation of response to stimulus; GO:1902590 multi-organism organelle organization; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0051641 cellular localization; GO:0048524 positive regulation of viral process; GO:0046755 viral budding; GO:0007034 vacuolar transport; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0009057 macromolecule catabolic process; GO:0022402 cell cycle process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0042058 regulation of epidermal growth factor receptor signaling pathway; GO:0051128 regulation of cellular component organization; GO:1990182 exosomal secretion; GO:0040012 regulation of locomotion; GO:1903900 regulation of viral life cycle; GO:0009056 catabolic process; GO:0007032 endosome organization; GO:0007049 cell cycle; GO:0044089 positive regulation of cellular component biogenesis; GO:2000397 positive regulation of ubiquitin-dependent endocytosis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0036452 ESCRT complex; GO:0070013 intracellular organelle lumen; GO:0000813 ESCRT I complex; GO:0044425 membrane part; GO:0031902 late endosome membrane; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0005771 multivesicular body; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0010008 endosome membrane; GO:0005770 late endosome; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0003677 DNA binding; GO:0003714 transcription corepressor activity; GO:0031625 ubiquitin protein ligase binding; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:0003712 transcription cofactor activity; GO:0048306 calcium-dependent protein binding; GO:0032182 ubiquitin-like protein binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0042802 identical protein binding; GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity; GO:0005488 binding; GO:0042803 protein homodimerization activity; GO:0003676 nucleic acid binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0043130 ubiquitin binding; GO:0003713 transcription coactivator activity; GO:0044389 ubiquitin-like protein ligase binding; GO:0000988 transcription factor activity, protein binding; GO:0046790 virion binding; GO:0019899 enzyme binding; ","K12183","TSG101; ESCRT-I complex subunit TSG101","hsa04144 Endocytosis - Homo sapiens (human); ","IPR016135; IPR008883; IPR017916; ","\"Ubiquitin-conjugating enzyme/RWD-like; Ubiquitin E2 variant, N-terminal; Steadiness box (SB) domain; \"\r"]
["Q99832","T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7","CCT7",59.366,134.52,38.5,16,23,16,0.927,0.899,0.907,1.07,1.102,1.074,1.188,1.84E-4,"cytoplasm\r","GO:0065008 regulation of biological quality; GO:0035036 sperm-egg recognition; GO:0022414 reproductive process; GO:0061077 chaperone-mediated protein folding; GO:0009891 positive regulation of biosynthetic process; GO:0044699 single-organism process; GO:1901998 toxin transport; GO:1904816 positive regulation of protein localization to chromosome, telomeric region; GO:0032204 regulation of telomere maintenance; GO:0051234 establishment of localization; GO:1904851 positive regulation of establishment of protein localization to telomere; GO:0051130 positive regulation of cellular component organization; GO:0006457 protein folding; GO:0006458 'de novo' protein folding; GO:0009893 positive regulation of metabolic process; GO:0032879 regulation of localization; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0032846 positive regulation of homeostatic process; GO:0044702 single organism reproductive process; GO:1904874 positive regulation of telomerase RNA localization to Cajal body; GO:0031326 regulation of cellular biosynthetic process; GO:0051054 positive regulation of DNA metabolic process; GO:0080090 regulation of primary metabolic process; GO:0007339 binding of sperm to zona pellucida; GO:0019953 sexual reproduction; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0032212 positive regulation of telomere maintenance via telomerase; GO:0031323 regulation of cellular metabolic process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0009566 fertilization; GO:0050789 regulation of biological process; GO:0051052 regulation of DNA metabolic process; GO:0010638 positive regulation of organelle organization; GO:1900180 regulation of protein localization to nucleus; GO:2001252 positive regulation of chromosome organization; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0070202 regulation of establishment of protein localization to chromosome; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0000003 reproduction; GO:0050794 regulation of cellular process; GO:0032210 regulation of telomere maintenance via telomerase; GO:1903829 positive regulation of cellular protein localization; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0009988 cell-cell recognition; GO:0032844 regulation of homeostatic process; GO:0008037 cell recognition; GO:0070201 regulation of establishment of protein localization; GO:0060341 regulation of cellular localization; GO:1904356 regulation of telomere maintenance via telomere lengthening; GO:0009889 regulation of biosynthetic process; GO:1904871 positive regulation of protein localization to Cajal body; GO:0051171 regulation of nitrogen compound metabolic process; GO:0032880 regulation of protein localization; GO:0009987 cellular process; GO:1904872 regulation of telomerase RNA localization to Cajal body; GO:1904869 regulation of protein localization to Cajal body; GO:1904814 regulation of protein localization to chromosome, telomeric region; GO:1904358 positive regulation of telomere maintenance via telomere lengthening; GO:0033043 regulation of organelle organization; GO:0010556 regulation of macromolecule biosynthetic process; GO:0007338 single fertilization; GO:2000278 regulation of DNA biosynthetic process; GO:0048518 positive regulation of biological process; GO:0033044 regulation of chromosome organization; GO:1900182 positive regulation of protein localization to nucleus; GO:1904951 positive regulation of establishment of protein localization; GO:0070203 regulation of establishment of protein localization to telomere; GO:0044703 multi-organism reproductive process; GO:0031325 positive regulation of cellular metabolic process; GO:0032206 positive regulation of telomere maintenance; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0031647 regulation of protein stability; GO:0051128 regulation of cellular component organization; GO:0031328 positive regulation of cellular biosynthetic process; GO:0051179 localization; GO:2000573 positive regulation of DNA biosynthetic process; GO:0050821 protein stabilization; GO:1903827 regulation of cellular protein localization; GO:0065007 biological regulation; ","GO:0044421 extracellular region part; GO:0005874 microtubule; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0005623 cell; GO:0099080 supramolecular complex; GO:0044422 organelle part; GO:0002199 zona pellucida receptor complex; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005856 cytoskeleton; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0044445 cytosolic part; GO:0043227 membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0005832 chaperonin-containing T-complex; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0099081 supramolecular polymer; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0101031 chaperone complex; GO:0044297 cell body; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0044183 protein binding involved in protein folding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0042802 identical protein binding; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0051082 unfolded protein binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K09499",null,null,"IPR027410; IPR027409; IPR027413; ","TCP-1-like chaperonin intermediate domain; GroEL-like apical domain; GroEL-like equatorial domain; \r"]
["Q99933","BAG family molecular chaperone regulator 1 OS=Homo sapiens OX=9606 GN=BAG1","BAG1",38.778,2.6266,2.9,1,1,1,1.204,1.054,0.94,1.042,0.824,0.962,0.884,0.285,"nucleus\r","GO:0044700 single organism signaling; GO:0050794 regulation of cellular process; GO:0010941 regulation of cell death; GO:0043069 negative regulation of programmed cell death; GO:0007166 cell surface receptor signaling pathway; GO:0061077 chaperone-mediated protein folding; GO:0043067 regulation of programmed cell death; GO:0044699 single-organism process; GO:0080134 regulation of response to stress; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:0006457 protein folding; GO:0070389 chaperone cofactor-dependent protein refolding; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0043066 negative regulation of apoptotic process; GO:0006915 apoptotic process; GO:0009987 cellular process; GO:0051716 cellular response to stimulus; GO:0044763 single-organism cellular process; GO:0023052 signaling; GO:0050789 regulation of biological process; GO:0080135 regulation of cellular response to stress; GO:0008219 cell death; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:1900034 regulation of cellular response to heat; GO:0065009 regulation of molecular function; GO:0012501 programmed cell death; GO:0060548 negative regulation of cell death; GO:0042981 regulation of apoptotic process; GO:0042026 protein refolding; GO:0065007 biological regulation; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0051087 chaperone binding; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0098772 molecular function regulator; GO:0004871 signal transducer activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0005057 signal transducer activity, downstream of receptor; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0030554 adenyl nucleotide binding; GO:0060590 ATPase regulator activity; GO:0000774 adenyl-nucleotide exchange factor activity; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; ","K09555","BAG1; BCL2-associated athanogene 1","hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); ","IPR003103; IPR029071; IPR000626; ","BAG domain; Ubiquitin-related domain; Ubiquitin domain; \r"]
["Q99969","Retinoic acid receptor responder protein 2 OS=Homo sapiens OX=9606 GN=RARRES2","RARRES2",18.617,16.526,14.1,2,3,2,1.157,1.214,1.133,0.815,0.853,0.858,0.721,0.000237,"extracellular\r","GO:0030335 positive regulation of cell migration; GO:0032270 positive regulation of cellular protein metabolic process; GO:0043009 chordate embryonic development; GO:0044255 cellular lipid metabolic process; GO:0019216 regulation of lipid metabolic process; GO:0044237 cellular metabolic process; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0032879 regulation of localization; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0050921 positive regulation of chemotaxis; GO:0009790 embryo development; GO:2001273 regulation of glucose import in response to insulin stimulus; GO:0046324 regulation of glucose import; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0010759 positive regulation of macrophage chemotaxis; GO:0080090 regulation of primary metabolic process; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0051272 positive regulation of cellular component movement; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0006935 chemotaxis; GO:0006810 transport; GO:0048513 animal organ development; GO:0001701 in utero embryonic development; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:0010604 positive regulation of macromolecule metabolic process; GO:0016101 diterpenoid metabolic process; GO:0042330 taxis; GO:0002682 regulation of immune system process; GO:0002685 regulation of leukocyte migration; GO:0050994 regulation of lipid catabolic process; GO:0051094 positive regulation of developmental process; GO:0071675 regulation of mononuclear cell migration; GO:0002687 positive regulation of leukocyte migration; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0031399 regulation of protein modification process; GO:0002576 platelet degranulation; GO:2000147 positive regulation of cell motility; GO:0045597 positive regulation of cell differentiation; GO:1902578 single-organism localization; GO:2000145 regulation of cell motility; GO:0007275 multicellular organism development; GO:0006720 isoprenoid metabolic process; GO:0006950 response to stress; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0055123 digestive system development; GO:0030334 regulation of cell migration; GO:0032101 regulation of response to external stimulus; GO:0044238 primary metabolic process; GO:0045055 regulated exocytosis; GO:0051247 positive regulation of protein metabolic process; GO:0048565 digestive tract development; GO:0031325 positive regulation of cellular metabolic process; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0006887 exocytosis; GO:0040017 positive regulation of locomotion; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0051234 establishment of localization; GO:0009893 positive regulation of metabolic process; GO:0032103 positive regulation of response to external stimulus; GO:0010827 regulation of glucose transport; GO:0050873 brown fat cell differentiation; GO:0006629 lipid metabolic process; GO:0032502 developmental process; GO:0035295 tube development; GO:0045937 positive regulation of phosphate metabolic process; GO:0010828 positive regulation of glucose transport; GO:0002688 regulation of leukocyte chemotaxis; GO:0048522 positive regulation of cellular process; GO:0051050 positive regulation of transport; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0042221 response to chemical; GO:0032940 secretion by cell; GO:0006954 inflammatory response; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0040011 locomotion; GO:0006952 defense response; GO:0045444 fat cell differentiation; GO:0048856 anatomical structure development; GO:0071622 regulation of granulocyte chemotaxis; GO:0060255 regulation of macromolecule metabolic process; GO:0048568 embryonic organ development; GO:0046326 positive regulation of glucose import; GO:1900076 regulation of cellular response to insulin stimulus; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0002690 positive regulation of leukocyte chemotaxis; GO:0045600 positive regulation of fat cell differentiation; GO:0001523 retinoid metabolic process; GO:0009987 cellular process; GO:0048566 embryonic digestive tract development; GO:1905521 regulation of macrophage migration; GO:0045595 regulation of cell differentiation; GO:2001275 positive regulation of glucose import in response to insulin stimulus; GO:0051049 regulation of transport; GO:0009792 embryo development ending in birth or egg hatching; GO:0001932 regulation of protein phosphorylation; GO:0031401 positive regulation of protein modification process; GO:0050920 regulation of chemotaxis; GO:0001934 positive regulation of protein phosphorylation; GO:0048518 positive regulation of biological process; GO:1900078 positive regulation of cellular response to insulin stimulus; GO:0045598 regulation of fat cell differentiation; GO:1905523 positive regulation of macrophage migration; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0002684 positive regulation of immune system process; GO:0006721 terpenoid metabolic process; GO:0010758 regulation of macrophage chemotaxis; GO:0040012 regulation of locomotion; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0042827 platelet dense granule; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0031012 extracellular matrix; GO:0043226 organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0031089 platelet dense granule lumen; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005102 receptor binding; GO:0005488 binding; ","K10044"]
["Q9BPX5","Actin-related protein 2/3 complex subunit 5-like protein OS=Homo sapiens OX=9606 GN=ARPC5L","ARPC5L",16.941,29.62,40.5,5,7,5,0.971,0.777,0.963,1.142,0.972,1.12,1.193,0.114,"nucleus\r","GO:0030833 regulation of actin filament polymerization; GO:0050794 regulation of cellular process; GO:0016477 cell migration; GO:0016043 cellular component organization; GO:0034314 Arp2/3 complex-mediated actin nucleation; GO:0065008 regulation of biological quality; GO:0032273 positive regulation of protein polymerization; GO:0051674 localization of cell; GO:0032956 regulation of actin cytoskeleton organization; GO:0007015 actin filament organization; GO:0044699 single-organism process; GO:0044087 regulation of cellular component biogenesis; GO:0030832 regulation of actin filament length; GO:0051130 positive regulation of cellular component organization; GO:0030036 actin cytoskeleton organization; GO:0045010 actin nucleation; GO:0032535 regulation of cellular component size; GO:0032271 regulation of protein polymerization; GO:0031334 positive regulation of protein complex assembly; GO:0051493 regulation of cytoskeleton organization; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0051495 positive regulation of cytoskeleton organization; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0033043 regulation of organelle organization; GO:0032970 regulation of actin filament-based process; GO:0048870 cell motility; GO:0030838 positive regulation of actin filament polymerization; GO:0048518 positive regulation of biological process; GO:1902589 single-organism organelle organization; GO:0008064 regulation of actin polymerization or depolymerization; GO:0050789 regulation of biological process; GO:0043254 regulation of protein complex assembly; GO:0010638 positive regulation of organelle organization; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0090066 regulation of anatomical structure size; GO:0006928 movement of cell or subcellular component; GO:1902905 positive regulation of supramolecular fiber organization; GO:0051128 regulation of cellular component organization; GO:0040011 locomotion; GO:0051179 localization; GO:0097435 supramolecular fiber organization; GO:0044089 positive regulation of cellular component biogenesis; GO:1902903 regulation of supramolecular fiber organization; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0030054 cell junction; GO:0044430 cytoskeletal part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0070161 anchoring junction; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0015629 actin cytoskeleton; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005856 cytoskeleton; GO:0005885 Arp2/3 protein complex; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030055 cell-substrate junction; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0005924 cell-substrate adherens junction; ","GO:0051015 actin filament binding; GO:0008092 cytoskeletal protein binding; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0003779 actin binding; GO:0005515 protein binding; GO:0032403 protein complex binding; ","K05754","ARPC5; actin related protein 2/3 complex, subunit 5","hsa05100 Bacterial invasion of epithelial cells - Homo sapiens (human); hsa05132 Salmonella infection - Homo sapiens (human); hsa04666 Fc gamma R-mediated phagocytosis - Homo sapiens (human); hsa04144 Endocytosis - Homo sapiens (human); hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human); hsa05131 Shigellosis - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); "]
["Q9BQ69","O-acetyl-ADP-ribose deacetylase MACROD1 OS=Homo sapiens OX=9606 GN=MACROD1","MACROD1",35.505,20.93,14.8,3,4,3,0.967,0.977,0.951,1.104,0.931,1.077,1.075,0.325,"mitochondria\r","GO:0033554 cellular response to stress; GO:0042278 purine nucleoside metabolic process; GO:0009116 nucleoside metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0051725 protein de-ADP-ribosylation; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0051716 cellular response to stimulus; GO:0006950 response to stress; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0072521 purine-containing compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:0006974 cellular response to DNA damage stimulus; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:1901657 glycosyl compound metabolic process; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:1901564 organonitrogen compound metabolic process; ","GO:0043229 intracellular organelle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0019213 deacetylase activity; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016798 hydrolase activity, acting on glycosyl bonds; ",{"$nulls":3},"IPR002589; ","Macro domain; \r"]
["Q9BQ70","Transcription factor 25 OS=Homo sapiens OX=9606 GN=TCF25","TCF25",76.666,5.6164,2.5,2,2,2,0.95,0.984,0.932,1.175,0.775,1.192,1.096,0.657,"nucleus\r","GO:0097659 nucleic acid-templated transcription; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0051253 negative regulation of RNA metabolic process; GO:0044237 cellular metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0007507 heart development; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0043170 macromolecule metabolic process; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0000122 negative regulation of transcription from RNA polymerase II promoter; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0032501 multicellular organismal process; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:1902679 negative regulation of RNA biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0048856 anatomical structure development; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0072359 circulatory system development; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0071704 organic substance metabolic process; GO:0045892 negative regulation of transcription, DNA-templated; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0009059 macromolecule biosynthetic process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0048731 system development; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0051252 regulation of RNA metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0009890 negative regulation of biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044767 single-organism developmental process; GO:0010467 gene expression; GO:0031327 negative regulation of cellular biosynthetic process; GO:0065007 biological regulation; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003677 DNA binding; GO:0005488 binding; GO:0001071 nucleic acid binding transcription factor activity; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0003700 transcription factor activity, sequence-specific DNA binding; ",{"$nulls":3},"IPR011990; ","Tetratricopeptide-like helical domain; \r"]
["Q9BQA9","Uncharacterized protein C17orf62 OS=Homo sapiens OX=9606 GN=C17orf62","C17orf62",20.774,4.4095,8.6,2,2,2,0.975,1.085,1.026,0.908,0.985,1.031,0.948,0.324,"mitochondria\r",null,"GO:0031224 intrinsic component of membrane; GO:0016020 membrane; GO:0016021 integral component of membrane; GO:0044425 membrane part; ","GO:0005515 protein binding; GO:0005488 binding; "]
["Q9BQG0","Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A","MYBBP1A",148.85,29.969,7.2,8,9,8,0.754,0.865,0.962,1.168,1.19,1.051,1.321,0.0248,"nucleus\r","GO:0044700 single organism signaling; GO:0001649 osteoblast differentiation; GO:0010941 regulation of cell death; GO:0097659 nucleic acid-templated transcription; GO:0051169 nuclear transport; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0043170 macromolecule metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0090068 positive regulation of cell cycle process; GO:0051716 cellular response to stimulus; GO:0045815 positive regulation of gene expression, epigenetic; GO:0018130 heterocycle biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0001503 ossification; GO:0044763 single-organism cellular process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:1903506 regulation of nucleic acid-templated transcription; GO:2000210 positive regulation of anoikis; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0022900 electron transport chain; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006913 nucleocytoplasmic transport; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0043068 positive regulation of programmed cell death; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0044707 single-multicellular organism process; GO:0033554 cellular response to stress; GO:0009267 cellular response to starvation; GO:0097190 apoptotic signaling pathway; GO:0006259 DNA metabolic process; GO:0043067 regulation of programmed cell death; GO:2000209 regulation of anoikis; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0045892 negative regulation of transcription, DNA-templated; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0045787 positive regulation of cell cycle; GO:0006950 response to stress; GO:0042149 cellular response to glucose starvation; GO:0072331 signal transduction by p53 class mediator; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0071496 cellular response to external stimulus; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0032922 circadian regulation of gene expression; GO:0031668 cellular response to extracellular stimulus; GO:0009890 negative regulation of biosynthetic process; GO:0012501 programmed cell death; GO:0051179 localization; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0051253 negative regulation of RNA metabolic process; GO:0051234 establishment of localization; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0006915 apoptotic process; GO:0051726 regulation of cell cycle; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0032502 developmental process; GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0055114 oxidation-reduction process; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0010942 positive regulation of cell death; GO:0007623 circadian rhythm; GO:0016070 RNA metabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0015980 energy derivation by oxidation of organic compounds; GO:1902679 negative regulation of RNA biosynthetic process; GO:0019222 regulation of metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0043065 positive regulation of apoptotic process; GO:0022904 respiratory electron transport chain; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0097193 intrinsic apoptotic signaling pathway; GO:0031669 cellular response to nutrient levels; GO:0071704 organic substance metabolic process; GO:0009991 response to extracellular stimulus; GO:0030154 cell differentiation; GO:0071897 DNA biosynthetic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0071156 regulation of cell cycle arrest; GO:0006355 regulation of transcription, DNA-templated; GO:0035556 intracellular signal transduction; GO:0010629 negative regulation of gene expression; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0045333 cellular respiration; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0040029 regulation of gene expression, epigenetic; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0048511 rhythmic process; GO:0071158 positive regulation of cell cycle arrest; GO:0042594 response to starvation; GO:0010467 gene expression; GO:0031667 response to nutrient levels; GO:0031327 negative regulation of cellular biosynthetic process; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0042564 NLS-dependent protein nuclear import complex; GO:0044424 intracellular part; GO:0005730 nucleolus; GO:0005623 cell; GO:0044422 organelle part; GO:0031074 nucleocytoplasmic shuttling complex; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0043234 protein complex; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0003677 DNA binding; GO:0003723 RNA binding; GO:0003714 transcription corepressor activity; GO:0005515 protein binding; GO:0043565 sequence-specific DNA binding; GO:0003712 transcription cofactor activity; GO:0001047 core promoter binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0000975 regulatory region DNA binding; GO:0001067 regulatory region nucleic acid binding; GO:0016779 nucleotidyltransferase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0044212 transcription regulatory region DNA binding; GO:0003676 nucleic acid binding; GO:0034061 DNA polymerase activity; GO:0000989 transcription factor activity, transcription factor binding; GO:0003887 DNA-directed DNA polymerase activity; GO:0016740 transferase activity; GO:0000988 transcription factor activity, protein binding; GO:0008134 transcription factor binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K02331",null,null,"IPR016024; ","Armadillo-type fold; \r"]
["Q9BQS8","FYVE and coiled-coil domain-containing protein 1 OS=Homo sapiens OX=9606 GN=FYCO1","FYCO1",166.98,76.83,10.8,13,15,13,1.061,1.064,1.044,0.952,0.95,0.961,0.903,1.22E-4,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0072384 organelle transport along microtubule; GO:0051640 organelle localization; GO:0046907 intracellular transport; GO:0031331 positive regulation of cellular catabolic process; GO:0061077 chaperone-mediated protein folding; GO:0044699 single-organism process; GO:0030705 cytoskeleton-dependent intracellular transport; GO:0099111 microtubule-based transport; GO:1901096 regulation of autophagosome maturation; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0006457 protein folding; GO:0010970 transport along microtubule; GO:0006458 'de novo' protein folding; GO:0051649 establishment of localization in cell; GO:1902578 single-organism localization; GO:0009893 positive regulation of metabolic process; GO:0009896 positive regulation of catabolic process; GO:0051648 vesicle localization; GO:1901098 positive regulation of autophagosome maturation; GO:1902580 single-organism cellular localization; GO:0072386 plus-end-directed organelle transport along microtubule; GO:0009987 cellular process; GO:0044765 single-organism transport; GO:0051650 establishment of vesicle localization; GO:0044088 regulation of vacuole organization; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0033043 regulation of organelle organization; GO:0031323 regulation of cellular metabolic process; GO:0051656 establishment of organelle localization; GO:0010506 regulation of autophagy; GO:0048518 positive regulation of biological process; GO:0007017 microtubule-based process; GO:1902582 single-organism intracellular transport; GO:0051641 cellular localization; GO:0047496 vesicle transport along microtubule; GO:0016241 regulation of macroautophagy; GO:0006810 transport; GO:0007018 microtubule-based movement; GO:0099518 vesicle cytoskeletal trafficking; GO:0050789 regulation of biological process; GO:0072383 plus-end-directed vesicle transport along microtubule; GO:0010638 positive regulation of organelle organization; GO:0010508 positive regulation of autophagy; GO:0031325 positive regulation of cellular metabolic process; GO:0016239 positive regulation of macroautophagy; GO:0019222 regulation of metabolic process; GO:0044090 positive regulation of vacuole organization; GO:0006928 movement of cell or subcellular component; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0065007 biological regulation; ","GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005770 late endosome; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005776 autophagosome; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005764 lysosome; GO:0005773 vacuole; GO:0005768 endosome; GO:0005794 Golgi apparatus; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0000323 lytic vacuole; ","GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0051082 unfolded protein binding; GO:0044183 protein binding involved in protein folding; GO:0005488 binding; GO:0043167 ion binding; ",{"$nulls":3},"IPR000306; IPR017455; IPR013083; IPR004012; IPR011011; IPR009038; ","\"FYVE zinc finger; Zinc finger, FYVE-related; Zinc finger, RING/FYVE/PHD-type; RUN domain; Zinc finger, FYVE/PHD-type; GOLD domain; \"\r"]
["Q9BRA2","Thioredoxin domain-containing protein 17 OS=Homo sapiens OX=9606 GN=TXNDC17","TXNDC17",13.941,23.027,43.9,5,11,5,0.907,0.855,0.936,1.024,1.126,1.094,1.202,0.00886,"extracellular\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0051716 cellular response to stimulus; GO:0034097 response to cytokine; GO:0007166 cell surface receptor signaling pathway; GO:0071356 cellular response to tumor necrosis factor; GO:0055114 oxidation-reduction process; GO:0071310 cellular response to organic substance; GO:0009636 response to toxic substance; GO:0044699 single-organism process; GO:0010033 response to organic substance; GO:0023052 signaling; GO:0050896 response to stimulus; GO:0071345 cellular response to cytokine stimulus; GO:0033209 tumor necrosis factor-mediated signaling pathway; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:1990748 cellular detoxification; GO:0007154 cell communication; GO:0044710 single-organism metabolic process; GO:0034612 response to tumor necrosis factor; GO:0098869 cellular oxidant detoxification; GO:0019221 cytokine-mediated signaling pathway; GO:0098754 detoxification; GO:0009987 cellular process; GO:0070887 cellular response to chemical stimulus; GO:0065007 biological regulation; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0015036 disulfide oxidoreductase activity; GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:0003824 catalytic activity; GO:0005488 binding; GO:0047134 protein-disulfide reductase activity; GO:0016667 oxidoreductase activity, acting on a sulfur group of donors; GO:0016209 antioxidant activity; GO:0005515 protein binding; GO:0004601 peroxidase activity; GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor; GO:0016684 oxidoreductase activity, acting on peroxide as acceptor; GO:0016491 oxidoreductase activity; ",{"$nulls":3},"IPR012336; ","Thioredoxin-like fold; \r"]
["Q9BRJ7","Tudor-interacting repair regulator protein OS=Homo sapiens OX=9606 GN=NUDT16L1","NUDT16L1",23.338,11.22,17.1,3,4,2,0.914,1.036,0.859,1.077,1.063,1.056,1.138,0.14,"cytoplasm\r",null,"GO:0044424 intracellular part; GO:0005623 cell; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; ","GO:0030515 snoRNA binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0016787 hydrolase activity; GO:0005515 protein binding; ","K16867","NUDT16L1; NUDT16-like protein 1","hsa05205 Proteoglycans in cancer - Homo sapiens (human); ","IPR015797; ","NUDIX hydrolase domain-like; \r"]
["Q9BRR6","ADP-dependent glucokinase OS=Homo sapiens OX=9606 GN=ADPGK","ADPGK",54.088,4.717,2.6,1,2,1,1.017,0.942,0.98,1.013,1.074,0.98,1.044,0.289,"extracellular\r","GO:0006757 ATP generation from ADP; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0006165 nucleoside diphosphate phosphorylation; GO:0046031 ADP metabolic process; GO:0019362 pyridine nucleotide metabolic process; GO:0006096 glycolytic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009185 ribonucleoside diphosphate metabolic process; GO:0046939 nucleotide phosphorylation; GO:0009135 purine nucleoside diphosphate metabolic process; GO:0072524 pyridine-containing compound metabolic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0006006 glucose metabolic process; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0006753 nucleoside phosphate metabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0009179 purine ribonucleoside diphosphate metabolic process; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0006732 coenzyme metabolic process; GO:0005975 carbohydrate metabolic process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0016052 carbohydrate catabolic process; GO:0051186 cofactor metabolic process; GO:1901575 organic substance catabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0006082 organic acid metabolic process; GO:0043436 oxoacid metabolic process; GO:0016310 phosphorylation; GO:0006725 cellular aromatic compound metabolic process; GO:0046496 nicotinamide nucleotide metabolic process; GO:0009259 ribonucleotide metabolic process; GO:0071704 organic substance metabolic process; GO:0006090 pyruvate metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0005996 monosaccharide metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0009987 cellular process; GO:0009119 ribonucleoside metabolic process; GO:0009132 nucleoside diphosphate metabolic process; GO:0046034 ATP metabolic process; GO:0044724 single-organism carbohydrate catabolic process; GO:0044712 single-organism catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0006163 purine nucleotide metabolic process; GO:0046128 purine ribonucleoside metabolic process; GO:0006793 phosphorus metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0009056 catabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0019318 hexose metabolic process; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0005576 extracellular region; GO:0044444 cytoplasmic part; ","GO:0016301 kinase activity; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0016740 transferase activity; GO:0043843 ADP-specific glucokinase activity; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K08074","ADPGK; ADP-dependent glucokinase [EC:2.7.1.147]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); ","IPR029056; ","Ribokinase-like; \r"]
["Q9BRX8","Redox-regulatory protein FAM213A OS=Homo sapiens OX=9606 GN=FAM213A","FAM213A",25.764,55.23,29.3,6,18,6,1.127,1.17,1.151,0.904,0.851,0.839,0.752,3.57E-4,"extracellular\r","GO:0050794 regulation of cellular process; GO:0055114 oxidation-reduction process; GO:0009636 response to toxic substance; GO:0045637 regulation of myeloid cell differentiation; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:1903706 regulation of hemopoiesis; GO:0008152 metabolic process; GO:1990748 cellular detoxification; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0044710 single-organism metabolic process; GO:1902105 regulation of leukocyte differentiation; GO:0002761 regulation of myeloid leukocyte differentiation; GO:0002682 regulation of immune system process; GO:0098869 cellular oxidant detoxification; GO:0045670 regulation of osteoclast differentiation; GO:0009987 cellular process; GO:0098754 detoxification; GO:0050793 regulation of developmental process; GO:0045595 regulation of cell differentiation; GO:0065007 biological regulation; GO:2000026 regulation of multicellular organismal development; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016209 antioxidant activity; "]
["Q9BS26","Endoplasmic reticulum resident protein 44 OS=Homo sapiens OX=9606 GN=ERP44","ERP44",46.971,109.15,36,14,27,14,0.962,0.965,1.008,1.008,1.062,1.02,1.053,0.078,"extracellular\r","GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0002283 neutrophil activation involved in immune response; GO:0034976 response to endoplasmic reticulum stress; GO:0002252 immune effector process; GO:0045454 cell redox homeostasis; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:0071704 organic substance metabolic process; GO:0006457 protein folding; GO:0042592 homeostatic process; GO:0008152 metabolic process; GO:0035966 response to topologically incorrect protein; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:1901135 carbohydrate derivative metabolic process; GO:0036230 granulocyte activation; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0009987 cellular process; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0006986 response to unfolded protein; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0006950 response to stress; GO:0002446 neutrophil mediated immunity; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0019725 cellular homeostasis; GO:0009100 glycoprotein metabolic process; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0043312 neutrophil degranulation; GO:0044238 primary metabolic process; GO:0002263 cell activation involved in immune response; GO:0002444 myeloid leukocyte mediated immunity; GO:0006810 transport; GO:0002366 leukocyte activation involved in immune response; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0032940 secretion by cell; GO:0044260 cellular macromolecule metabolic process; GO:0001775 cell activation; GO:0043299 leukocyte degranulation; GO:0051179 localization; GO:0006955 immune response; GO:0006887 exocytosis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0034774 secretory granule lumen; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005788 endoplasmic reticulum lumen; GO:0097708 intracellular vesicle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0035580 specific granule lumen; GO:0044432 endoplasmic reticulum part; GO:0005793 endoplasmic reticulum-Golgi intermediate compartment; GO:0042581 specific granule; GO:0009986 cell surface; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds; GO:0005515 protein binding; GO:0016853 isomerase activity; GO:0016860 intramolecular oxidoreductase activity; GO:0003756 protein disulfide isomerase activity; GO:0003824 catalytic activity; GO:0005488 binding; ","K17264",null,null,"IPR013766; IPR012336; ","Thioredoxin domain; Thioredoxin-like fold; \r"]
["Q9BSD7","Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR","NTPCR",20.713,2.814,5.8,1,1,1,0.983,1.102,1.036,1.085,1.014,0.8,0.929,0.455,"cyto_mito\r","GO:0008152 metabolic process; GO:0016311 dephosphorylation; GO:0044237 cellular metabolic process; GO:0006793 phosphorus metabolic process; GO:0009987 cellular process; GO:0006796 phosphate-containing compound metabolic process; ","GO:0016020 membrane; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:0003723 RNA binding; GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0016791 phosphatase activity; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0042578 phosphoric ester hydrolase activity; GO:0032553 ribonucleotide binding; GO:0098519 nucleotide phosphatase activity, acting on free nucleotides; GO:0005488 binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0003676 nucleic acid binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K06928","NTPCR; nucleoside-triphosphatase [EC:3.6.1.15]","hsa00730 Thiamine metabolism - Homo sapiens (human); hsa00230 Purine metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR003593; IPR027417; ","AAA+ ATPase domain; P-loop containing nucleoside triphosphate hydrolase; \r"]
["Q9BSL1","Ubiquitin-associated domain-containing protein 1 OS=Homo sapiens OX=9606 GN=UBAC1","UBAC1",45.338,17.421,5.2,2,4,2,0.928,0.987,0.969,1.062,1.028,1.044,1.087,0.0154,"cytoplasm\r","GO:0008152 metabolic process; GO:0032446 protein modification by small protein conjugation; GO:0016567 protein ubiquitination; GO:0044260 cellular macromolecule metabolic process; GO:0044267 cellular protein metabolic process; GO:0006464 cellular protein modification process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:0044238 primary metabolic process; GO:0009987 cellular process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; ","GO:0016020 membrane; GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0005794 Golgi apparatus; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ","K12174",null,null,"IPR006636; IPR015940; IPR029071; IPR009060; ","Heat shock chaperonin-binding; Ubiquitin-associated domain; Ubiquitin-related domain; UBA-like; \r"]
["Q9BT78","COP9 signalosome complex subunit 4 OS=Homo sapiens OX=9606 GN=COPS4","COPS4",46.268,73.499,30.3,9,13,9,0.916,1.025,1.01,1.044,1.017,0.985,1.032,0.451,"cytoplasm\r","GO:0016043 cellular component organization; GO:0033554 cellular response to stress; GO:0000338 protein deneddylation; GO:0070646 protein modification by small protein removal; GO:0006283 transcription-coupled nucleotide-excision repair; GO:0006725 cellular aromatic compound metabolic process; GO:0006259 DNA metabolic process; GO:0006289 nucleotide-excision repair; GO:0044267 cellular protein metabolic process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0006508 proteolysis; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0009987 cellular process; GO:0051716 cellular response to stimulus; GO:0006950 response to stress; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0044238 primary metabolic process; GO:0006974 cellular response to DNA damage stimulus; GO:0000715 nucleotide-excision repair, DNA damage recognition; GO:0006281 DNA repair; GO:0051276 chromosome organization; GO:0090304 nucleic acid metabolic process; GO:0006996 organelle organization; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:0071840 cellular component organization or biogenesis; ","GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0008180 COP9 signalosome; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0070382 exocytic vesicle; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0008021 synaptic vesicle; GO:0016607 nuclear speck; GO:0098793 presynapse; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0044451 nucleoplasm part; GO:0044456 synapse part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0045202 synapse; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0043234 protein complex; GO:0030133 transport vesicle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0019784 NEDD8-specific protease activity; GO:0008233 peptidase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0019783 ubiquitin-like protein-specific protease activity; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0008234 cysteine-type peptidase activity; ","K12178",null,null,"IPR000717; IPR011991; ","Proteasome component (PCI) domain; Winged helix-turn-helix DNA-binding domain; \r"]
["Q9BTM9","Ubiquitin-related modifier 1 OS=Homo sapiens OX=9606 GN=URM1","URM1",11.38,4.8451,12.9,1,2,1,0.948,0.922,1.059,1.096,0.991,0.989,1.05,0.412,"nucleus\r","GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0006725 cellular aromatic compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0034227 tRNA thio-modification; GO:0044238 primary metabolic process; GO:0009451 RNA modification; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0002098 tRNA wobble uridine modification; GO:0016070 RNA metabolic process; GO:0008152 metabolic process; GO:0006399 tRNA metabolic process; GO:0046483 heterocycle metabolic process; GO:0002097 tRNA wobble base modification; GO:0090304 nucleic acid metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0008033 tRNA processing; GO:0044260 cellular macromolecule metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0010467 gene expression; GO:0043170 macromolecule metabolic process; GO:0006400 tRNA modification; GO:0043412 macromolecule modification; GO:0009987 cellular process; GO:0034660 ncRNA metabolic process; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ","K12161","URM1; ubiquitin related modifier 1","hsa04122 Sulfur relay system - Homo sapiens (human); ","IPR016155; IPR012675; ","\"Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp; Beta-grasp domain; \"\r"]
["Q9BTV4","Transmembrane protein 43 OS=Homo sapiens OX=9606 GN=TMEM43","TMEM43",44.875,51.339,32,13,19,13,1.129,1.109,1.078,0.852,0.937,0.927,0.819,0.0037,"plasma membrane\r","GO:0016043 cellular component organization; GO:0006997 nucleus organization; GO:0010256 endomembrane system organization; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0071763 nuclear membrane organization; GO:0044802 single-organism membrane organization; GO:0009987 cellular process; GO:0071840 cellular component organization or biogenesis; GO:0006998 nuclear envelope organization; ","GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0031965 nuclear membrane; GO:0031229 intrinsic component of nuclear inner membrane; GO:0031301 integral component of organelle membrane; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005639 integral component of nuclear inner membrane; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005637 nuclear inner membrane; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005788 endoplasmic reticulum lumen; GO:0005635 nuclear envelope; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0012505 endomembrane system; GO:0016021 integral component of membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0044432 endoplasmic reticulum part; GO:0031975 envelope; GO:0044453 nuclear membrane part; GO:0005794 Golgi apparatus; GO:0031300 intrinsic component of organelle membrane; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0043621 protein self-association; GO:0005488 binding; "]
["Q9BU23","Lipase maturation factor 2 OS=Homo sapiens OX=9606 GN=LMF2","LMF2",79.697,22.675,8.8,4,5,4,1.105,1.014,1.114,1.048,1.037,0.905,0.925,0.229,"plasma membrane\r",null,"GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044432 endoplasmic reticulum part; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; "]
["Q9BUF5","Tubulin beta-6 chain OS=Homo sapiens OX=9606 GN=TUBB6","TUBB6",49.857,57.116,40.6,13,41,5,0.981,0.913,0.952,1.066,1.049,1.041,1.109,0.00916,"cyto_nucl\r","GO:0016043 cellular component organization; GO:0007010 cytoskeleton organization; GO:0007017 microtubule-based process; GO:0009987 cellular process; GO:0006996 organelle organization; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0044421 extracellular region part; GO:0005874 microtubule; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0099081 supramolecular polymer; GO:0043228 non-membrane-bounded organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005856 cytoskeleton; GO:0005634 nucleus; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0005200 structural constituent of cytoskeleton; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0003924 GTPase activity; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019001 guanyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005525 GTP binding; GO:0005198 structural molecule activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0036094 small molecule binding; ","K07375","TUBB; tubulin beta","hsa04540 Gap junction - Homo sapiens (human); hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); ","IPR003008; IPR023123; IPR008280; IPR018316; ","\"Tubulin/FtsZ, GTPase domain; Tubulin, C-terminal; Tubulin/FtsZ, C-terminal; Tubulin/FtsZ, 2-layer sandwich domain; \"\r"]
["Q9BUJ2","Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1","HNRNPUL1",95.737,66.73,15.3,9,11,9,1.015,1.014,0.968,1.012,0.956,1.049,1.007,0.853,"nucleus\r","GO:0097659 nucleic acid-templated transcription; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0009607 response to biotic stimulus; GO:0009605 response to external stimulus; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0006396 RNA processing; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0051704 multi-organism process; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0016071 mRNA metabolic process; GO:0009615 response to virus; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0016032 viral process; GO:0000375 RNA splicing, via transesterification reactions; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0008380 RNA splicing; GO:0006355 regulation of transcription, DNA-templated; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:0051252 regulation of RNA metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0010467 gene expression; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0019899 enzyme binding; ","K15047","HNRNPUL1; heterogeneous nuclear ribonucleoprotein U-like protein 1","hsa05164 Influenza A - Homo sapiens (human); ","IPR003034; IPR027417; IPR001870; IPR013320; IPR003877; ","SAP domain; P-loop containing nucleoside triphosphate hydrolase; B30.2/SPRY domain; Concanavalin A-like lectin/glucanase domain; SPRY domain; \r"]
["Q9BUQ8","Probable ATP-dependent RNA helicase DDX23 OS=Homo sapiens OX=9606 GN=DDX23","DDX23",95.581,20.856,7.9,7,8,7,0.815,0.95,0.785,1.115,1.257,1.069,1.349,0.0166,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0016043 cellular component organization; GO:0022613 ribonucleoprotein complex biogenesis; GO:0022618 ribonucleoprotein complex assembly; GO:0006725 cellular aromatic compound metabolic process; GO:0045292 mRNA cis splicing, via spliceosome; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0008152 metabolic process; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0071826 ribonucleoprotein complex subunit organization; GO:0006139 nucleobase-containing compound metabolic process; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0000375 RNA splicing, via transesterification reactions; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0010501 RNA secondary structure unwinding; GO:0009987 cellular process; GO:0008380 RNA splicing; GO:0006396 RNA processing; GO:0034622 cellular macromolecular complex assembly; GO:0000354 cis assembly of pre-catalytic spliceosome; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:0090304 nucleic acid metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0000245 spliceosomal complex assembly; GO:0016071 mRNA metabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005681 spliceosomal complex; GO:0005576 extracellular region; GO:0097525 spliceosomal snRNP complex; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0071013 catalytic step 2 spliceosome; GO:1990904 ribonucleoprotein complex; GO:0030532 small nuclear ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0005682 U5 snRNP; GO:0043230 extracellular organelle; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0008026 ATP-dependent helicase activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0016887 ATPase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0004004 ATP-dependent RNA helicase activity; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003723 RNA binding; GO:0005524 ATP binding; GO:0070035 purine NTP-dependent helicase activity; GO:0004386 helicase activity; GO:0008186 RNA-dependent ATPase activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003724 RNA helicase activity; GO:0042623 ATPase activity, coupled; GO:0003676 nucleic acid binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; ","K12858","DDX23; ATP-dependent RNA helicase DDX23/PRP28 [EC:3.6.4.13]","hsa03040 Spliceosome - Homo sapiens (human); ","IPR014014; IPR011545; IPR014001; IPR027417; IPR001650; ","\"RNA helicase, DEAD-box type, Q motif; DEAD/DEAH box helicase domain; Helicase superfamily 1/2, ATP-binding domain; P-loop containing nucleoside triphosphate hydrolase; Helicase, C-terminal; \"\r"]
["Q9BUT1","3-hydroxybutyrate dehydrogenase type 2 OS=Homo sapiens OX=9606 GN=BDH2","BDH2",26.724,19.519,22.4,5,7,5,1.132,1.083,1.146,0.921,0.872,0.916,0.806,0.000905,"mitochondria\r","GO:0051188 cofactor biosynthetic process; GO:0065008 regulation of biological quality; GO:0006518 peptide metabolic process; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0030258 lipid modification; GO:1902224 ketone body metabolic process; GO:0055065 metal ion homeostasis; GO:0032787 monocarboxylic acid metabolic process; GO:0019748 secondary metabolic process; GO:0006629 lipid metabolic process; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0019395 fatty acid oxidation; GO:0009888 tissue development; GO:0050801 ion homeostasis; GO:0043043 peptide biosynthetic process; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0098771 inorganic ion homeostasis; GO:1901360 organic cyclic compound metabolic process; GO:0072329 monocarboxylic acid catabolic process; GO:0043603 cellular amide metabolic process; GO:0051186 cofactor metabolic process; GO:0046395 carboxylic acid catabolic process; GO:1901575 organic substance catabolic process; GO:0009237 siderophore metabolic process; GO:0044710 single-organism metabolic process; GO:0033013 tetrapyrrole metabolic process; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:0009062 fatty acid catabolic process; GO:0019184 nonribosomal peptide biosynthetic process; GO:0043436 oxoacid metabolic process; GO:0030855 epithelial cell differentiation; GO:0034440 lipid oxidation; GO:0055076 transition metal ion homeostasis; GO:0006725 cellular aromatic compound metabolic process; GO:0055072 iron ion homeostasis; GO:1901566 organonitrogen compound biosynthetic process; GO:0042168 heme metabolic process; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:0006778 porphyrin-containing compound metabolic process; GO:0046483 heterocycle metabolic process; GO:0055080 cation homeostasis; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0016042 lipid catabolic process; GO:0044711 single-organism biosynthetic process; GO:0042440 pigment metabolic process; GO:0044712 single-organism catabolic process; GO:0006635 fatty acid beta-oxidation; GO:0006807 nitrogen compound metabolic process; GO:0044282 small molecule catabolic process; GO:0006631 fatty acid metabolic process; GO:0044550 secondary metabolite biosynthetic process; GO:0046950 cellular ketone body metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0046951 ketone body biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0044767 single-organism developmental process; GO:0044283 small molecule biosynthetic process; GO:0019752 carboxylic acid metabolic process; GO:0016054 organic acid catabolic process; GO:0044242 cellular lipid catabolic process; GO:0043604 amide biosynthetic process; GO:0009056 catabolic process; GO:0019290 siderophore biosynthetic process; GO:0065007 biological regulation; GO:1901564 organonitrogen compound metabolic process; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; GO:0003858 3-hydroxybutyrate dehydrogenase activity; GO:0000166 nucleotide binding; GO:0048037 cofactor binding; GO:0016491 oxidoreductase activity; GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016614 oxidoreductase activity, acting on CH-OH group of donors; GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; GO:0003824 catalytic activity; GO:0051287 NAD binding; GO:0005488 binding; GO:0050662 coenzyme binding; GO:0036094 small molecule binding; ","K00019","E1.1.1.30; 3-hydroxybutyrate dehydrogenase [EC:1.1.1.30]","hsa00650 Butanoate metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00072 Synthesis and degradation of ketone bodies - Homo sapiens (human); ","IPR016040; ","NAD(P)-binding domain; \r"]
["Q9BV44","THUMP domain-containing protein 3 OS=Homo sapiens OX=9606 GN=THUMPD3","THUMPD3",57.002,3.5293,2,1,1,1,1.064,1.035,0.902,1.048,1.005,0.962,1.005,0.913,"cytoplasm\r","GO:0008152 metabolic process; GO:0032259 methylation; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0008168 methyltransferase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0016741 transferase activity, transferring one-carbon groups; GO:0016740 transferase activity; ",{"$nulls":3},"IPR000241; IPR029063; IPR004114; ","Putative RNA methylase domain; S-adenosyl-L-methionine-dependent methyltransferase; THUMP domain; \r"]
["Q9BVC6","Transmembrane protein 109 OS=Homo sapiens OX=9606 GN=TMEM109","TMEM109",26.21,11.295,12.8,3,9,3,1.065,1.066,0.973,0.956,0.94,0.951,0.917,0.0494,"plasma membrane\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0033554 cellular response to stress; GO:0010941 regulation of cell death; GO:0097190 apoptotic signaling pathway; GO:0009628 response to abiotic stimulus; GO:0010332 response to gamma radiation; GO:0044699 single-organism process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0097193 intrinsic apoptotic signaling pathway; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; GO:0032879 regulation of localization; GO:0006915 apoptotic process; GO:0009314 response to radiation; GO:0071479 cellular response to ionizing radiation; GO:0071478 cellular response to radiation; GO:0009987 cellular process; GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator; GO:0051716 cellular response to stimulus; GO:0071214 cellular response to abiotic stimulus; GO:0006950 response to stress; GO:0035556 intracellular signal transduction; GO:0051049 regulation of transport; GO:0072331 signal transduction by p53 class mediator; GO:0043269 regulation of ion transport; GO:0044763 single-organism cellular process; GO:0023052 signaling; GO:0006974 cellular response to DNA damage stimulus; GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage; GO:0034762 regulation of transmembrane transport; GO:0006810 transport; GO:0010212 response to ionizing radiation; GO:0050789 regulation of biological process; GO:0034765 regulation of ion transmembrane transport; GO:0008219 cell death; GO:0071480 cellular response to gamma radiation; GO:0006811 ion transport; GO:0012501 programmed cell death; GO:0051179 localization; GO:0060548 negative regulation of cell death; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0019867 outer membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0016528 sarcoplasm; GO:0005623 cell; GO:0044422 organelle part; GO:0005640 nuclear outer membrane; GO:0033017 sarcoplasmic reticulum membrane; GO:0070062 extracellular exosome; GO:0031965 nuclear membrane; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0031968 organelle outer membrane; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0005635 nuclear envelope; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0016529 sarcoplasmic reticulum; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044432 endoplasmic reticulum part; GO:0031975 envelope; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005244 voltage-gated ion channel activity; GO:0015075 ion transmembrane transporter activity; GO:0022838 substrate-specific channel activity; GO:0022803 passive transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0022836 gated channel activity; GO:0005216 ion channel activity; GO:0022832 voltage-gated channel activity; GO:0015267 channel activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0022857 transmembrane transporter activity; GO:0005215 transporter activity; "]
["Q9BVL2","Nucleoporin p58/p45 OS=Homo sapiens OX=9606 GN=NUP58","NUP58",60.896,7.9921,2.2,1,3,1,0.828,0.961,1.071,1.101,1.04,1.052,1.116,0.207,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:0050658 RNA transport; GO:1903533 regulation of protein targeting; GO:0051169 nuclear transport; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:1902583 multi-organism intracellular transport; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0032879 regulation of localization; GO:0065003 macromolecular complex assembly; GO:0015931 nucleobase-containing compound transport; GO:0033365 protein localization to organelle; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0006606 protein import into nucleus; GO:0075733 intracellular transport of virus; GO:0044419 interspecies interaction between organisms; GO:0008104 protein localization; GO:0044765 single-organism transport; GO:0051031 tRNA transport; GO:0007077 mitotic nuclear envelope disassembly; GO:0000278 mitotic cell cycle; GO:0018130 heterocycle biosynthetic process; GO:0044763 single-organism cellular process; GO:0032774 RNA biosynthetic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0006611 protein export from nucleus; GO:0051704 multi-organism process; GO:0051291 protein heterooligomerization; GO:0006810 transport; GO:0080135 regulation of cellular response to stress; GO:0031047 gene silencing by RNA; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0051223 regulation of protein transport; GO:0006464 cellular protein modification process; GO:0006913 nucleocytoplasmic transport; GO:1901362 organic cyclic compound biosynthetic process; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0016925 protein sumoylation; GO:0051260 protein homooligomerization; GO:1902593 single-organism nuclear import; GO:0051028 mRNA transport; GO:0044267 cellular protein metabolic process; GO:0080134 regulation of response to stress; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0051236 establishment of RNA localization; GO:0060341 regulation of cellular localization; GO:0051259 protein oligomerization; GO:0046483 heterocycle metabolic process; GO:1902578 single-organism localization; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0051081 nuclear envelope disassembly; GO:0044744 protein targeting to nucleus; GO:1902580 single-organism cellular localization; GO:0032880 regulation of protein localization; GO:0034613 cellular protein localization; GO:0006461 protein complex assembly; GO:0046794 transport of virus; GO:0006403 RNA localization; GO:0006405 RNA export from nucleus; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0044766 multi-organism transport; GO:0045184 establishment of protein localization; GO:0006409 tRNA export from nucleus; GO:0046822 regulation of nucleocytoplasmic transport; GO:0032446 protein modification by small protein conjugation; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0043412 macromolecule modification; GO:0051179 localization; GO:1903827 regulation of cellular protein localization; GO:0010256 endomembrane system organization; GO:0072594 establishment of protein localization to organelle; GO:0017038 protein import; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0051168 nuclear export; GO:1902581 multi-organism cellular localization; GO:0044764 multi-organism cellular process; GO:0051234 establishment of localization; GO:0071431 tRNA-containing ribonucleoprotein complex export from nucleus; GO:0006605 protein targeting; GO:0071427 mRNA-containing ribonucleoprotein complex export from nucleus; GO:0042306 regulation of protein import into nucleus; GO:0051649 establishment of localization in cell; GO:0050657 nucleic acid transport; GO:0022607 cellular component assembly; GO:0051262 protein tetramerization; GO:0051290 protein heterotetramerization; GO:0010827 regulation of glucose transport; GO:0033036 macromolecule localization; GO:0010468 regulation of gene expression; GO:0071822 protein complex subunit organization; GO:1901360 organic cyclic compound metabolic process; GO:0032386 regulation of intracellular transport; GO:0070647 protein modification by small protein conjugation or removal; GO:0010605 negative regulation of macromolecule metabolic process; GO:0071166 ribonucleoprotein complex localization; GO:1902582 single-organism intracellular transport; GO:0016070 RNA metabolic process; GO:0030397 membrane disassembly; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:1900180 regulation of protein localization to nucleus; GO:0019222 regulation of metabolic process; GO:1900034 regulation of cellular response to heat; GO:0019083 viral transcription; GO:0036211 protein modification process; GO:0070271 protein complex biogenesis; GO:0016043 cellular component organization; GO:0006997 nucleus organization; GO:1902579 multi-organism localization; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:1904589 regulation of protein import; GO:0070201 regulation of establishment of protein localization; GO:0071704 organic substance metabolic process; GO:0006998 nuclear envelope organization; GO:0018205 peptidyl-lysine modification; GO:0016032 viral process; GO:0019080 viral gene expression; GO:0006886 intracellular protein transport; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0033157 regulation of intracellular protein transport; GO:0006406 mRNA export from nucleus; GO:0070206 protein trimerization; GO:0010629 negative regulation of gene expression; GO:0051049 regulation of transport; GO:0006807 nitrogen compound metabolic process; GO:0044802 single-organism membrane organization; GO:0070208 protein heterotrimerization; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0043933 macromolecular complex subunit organization; GO:0018193 peptidyl-amino acid modification; GO:0070727 cellular macromolecule localization; GO:0016458 gene silencing; GO:0051170 nuclear import; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0071426 ribonucleoprotein complex export from nucleus; GO:0022411 cellular component disassembly; GO:0010467 gene expression; GO:0022402 cell cycle process; GO:0034504 protein localization to nucleus; GO:0071705 nitrogen compound transport; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005643 nuclear pore; GO:0031090 organelle membrane; GO:0005635 nuclear envelope; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0032991 macromolecular complex; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031965 nuclear membrane; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0031975 envelope; GO:0043227 membrane-bounded organelle; GO:0043234 protein complex; GO:0044428 nuclear part; ","GO:0005048 signal sequence binding; GO:0005487 nucleocytoplasmic transporter activity; GO:0042277 peptide binding; GO:0005488 binding; GO:0008139 nuclear localization sequence binding; GO:0005515 protein binding; GO:0033218 amide binding; GO:0005215 transporter activity; ","K14307","NUPL1; nucleoporin p58/p45","hsa03013 RNA transport - Homo sapiens (human); "]
["Q9BW27","Nuclear pore complex protein Nup85 OS=Homo sapiens OX=9606 GN=NUP85","NUP85",75.019,5.975,2,1,1,1,0.926,0.956,0.96,1.038,1.027,1.093,1.111,0.00926,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0050658 RNA transport; GO:0009891 positive regulation of biosynthetic process; GO:0051169 nuclear transport; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:1902583 multi-organism intracellular transport; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0032879 regulation of localization; GO:0015931 nucleobase-containing compound transport; GO:0033365 protein localization to organelle; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0006606 protein import into nucleus; GO:0075733 intracellular transport of virus; GO:0044419 interspecies interaction between organisms; GO:0008104 protein localization; GO:0051031 tRNA transport; GO:0044765 single-organism transport; GO:0030032 lamellipodium assembly; GO:0007077 mitotic nuclear envelope disassembly; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0007059 chromosome segregation; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044763 single-organism cellular process; GO:0032774 RNA biosynthetic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0048870 cell motility; GO:0031323 regulation of cellular metabolic process; GO:0006611 protein export from nucleus; GO:0006935 chemotaxis; GO:0051704 multi-organism process; GO:0006810 transport; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050900 leukocyte migration; GO:0080135 regulation of cellular response to stress; GO:0031047 gene silencing by RNA; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006913 nucleocytoplasmic transport; GO:0042330 taxis; GO:0006464 cellular protein modification process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016925 protein sumoylation; GO:0046907 intracellular transport; GO:1902593 single-organism nuclear import; GO:0051028 mRNA transport; GO:0044267 cellular protein metabolic process; GO:0080134 regulation of response to stress; GO:0048519 negative regulation of biological process; GO:0060326 cell chemotaxis; GO:1903047 mitotic cell cycle process; GO:0051236 establishment of RNA localization; GO:0046483 heterocycle metabolic process; GO:1902578 single-organism localization; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0051081 nuclear envelope disassembly; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0051171 regulation of nitrogen compound metabolic process; GO:0044744 protein targeting to nucleus; GO:1902680 positive regulation of RNA biosynthetic process; GO:1902580 single-organism cellular localization; GO:0034613 cellular protein localization; GO:1905517 macrophage migration; GO:0051254 positive regulation of RNA metabolic process; GO:0046794 transport of virus; GO:0006403 RNA localization; GO:0006405 RNA export from nucleus; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0071702 organic substance transport; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0030031 cell projection assembly; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0045184 establishment of protein localization; GO:0044766 multi-organism transport; GO:0051276 chromosome organization; GO:0006409 tRNA export from nucleus; GO:0032446 protein modification by small protein conjugation; GO:0098813 nuclear chromosome segregation; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0061024 membrane organization; GO:0006928 movement of cell or subcellular component; GO:0007062 sister chromatid cohesion; GO:0031328 positive regulation of cellular biosynthetic process; GO:0051179 localization; GO:0043412 macromolecule modification; GO:0097581 lamellipodium organization; GO:0010256 endomembrane system organization; GO:0072594 establishment of protein localization to organelle; GO:0051674 localization of cell; GO:0017038 protein import; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:1902581 multi-organism cellular localization; GO:0051168 nuclear export; GO:0044764 multi-organism cellular process; GO:0048246 macrophage chemotaxis; GO:0071431 tRNA-containing ribonucleoprotein complex export from nucleus; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:2001141 regulation of RNA biosynthetic process; GO:0000819 sister chromatid segregation; GO:0071427 mRNA-containing ribonucleoprotein complex export from nucleus; GO:0051649 establishment of localization in cell; GO:0050657 nucleic acid transport; GO:0097529 myeloid leukocyte migration; GO:0022607 cellular component assembly; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0033036 macromolecule localization; GO:0010827 regulation of glucose transport; GO:0070887 cellular response to chemical stimulus; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0070647 protein modification by small protein conjugation or removal; GO:0010605 negative regulation of macromolecule metabolic process; GO:1902582 single-organism intracellular transport; GO:0071166 ribonucleoprotein complex localization; GO:0016070 RNA metabolic process; GO:1902589 single-organism organelle organization; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0030397 membrane disassembly; GO:0090304 nucleic acid metabolic process; GO:0030030 cell projection organization; GO:1900034 regulation of cellular response to heat; GO:0019222 regulation of metabolic process; GO:0040011 locomotion; GO:0019083 viral transcription; GO:0036211 protein modification process; GO:1902579 multi-organism localization; GO:0016477 cell migration; GO:0006997 nucleus organization; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0006998 nuclear envelope organization; GO:0018205 peptidyl-lysine modification; GO:0016032 viral process; GO:0019080 viral gene expression; GO:0006886 intracellular protein transport; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006406 mRNA export from nucleus; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0051049 regulation of transport; GO:0006807 nitrogen compound metabolic process; GO:0044802 single-organism membrane organization; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0018193 peptidyl-amino acid modification; GO:0016458 gene silencing; GO:0070727 cellular macromolecule localization; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0030595 leukocyte chemotaxis; GO:0051170 nuclear import; GO:0071426 ribonucleoprotein complex export from nucleus; GO:0022411 cellular component disassembly; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0010467 gene expression; GO:0022402 cell cycle process; GO:0034504 protein localization to nucleus; GO:0071705 nitrogen compound transport; GO:0007049 cell cycle; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0000777 condensed chromosome kinetochore; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0044427 chromosomal part; GO:0005856 cytoskeleton; GO:0000793 condensed chromosome; GO:0031965 nuclear membrane; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0043227 membrane-bounded organelle; GO:0031080 nuclear pore outer ring; GO:0000776 kinetochore; GO:0043229 intracellular organelle; GO:0005643 nuclear pore; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005635 nuclear envelope; GO:0044430 cytoskeletal part; GO:0000779 condensed chromosome, centromeric region; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005819 spindle; GO:0098687 chromosomal region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0031975 envelope; GO:0000775 chromosome, centromeric region; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0017056 structural constituent of nuclear pore; GO:0005198 structural molecule activity; GO:0005488 binding; ","K14304","NUP85; nuclear pore complex protein Nup85","hsa03013 RNA transport - Homo sapiens (human); "]
["Q9BW83","Intraflagellar transport protein 27 homolog OS=Homo sapiens OX=9606 GN=IFT27","IFT27",20.48,6.7569,12.4,2,2,2,0.927,1.01,1.003,0.953,1.116,0.994,1.042,0.51,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0098840 protein transport along microtubule; GO:0060113 inner ear receptor cell differentiation; GO:0007166 cell surface receptor signaling pathway; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0022008 neurogenesis; GO:0060271 cilium assembly; GO:0044699 single-organism process; GO:0007224 smoothened signaling pathway; GO:0044782 cilium organization; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:0010970 transport along microtubule; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0044765 single-organism transport; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0007264 small GTPase mediated signal transduction; GO:0035735 intraciliary transport involved in cilium assembly; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:1902582 single-organism intracellular transport; GO:0006810 transport; GO:1902589 single-organism organelle organization; GO:0048513 animal organ development; GO:0043583 ear development; GO:0050789 regulation of biological process; GO:0030030 cell projection organization; GO:0060122 inner ear receptor stereocilium organization; GO:0099118 microtubule-based protein transport; GO:0090102 cochlea development; GO:0048856 anatomical structure development; GO:0031503 protein complex localization; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0044707 single-multicellular organism process; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0030705 cytoskeleton-dependent intracellular transport; GO:0099111 microtubule-based transport; GO:0030154 cell differentiation; GO:1902578 single-organism localization; GO:0070925 organelle assembly; GO:0006886 intracellular protein transport; GO:1902580 single-organism cellular localization; GO:0007275 multicellular organism development; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0035556 intracellular signal transduction; GO:0048731 system development; GO:0042490 mechanoreceptor differentiation; GO:0071702 organic substance transport; GO:0042073 intraciliary transport; GO:0048839 inner ear development; GO:0007017 microtubule-based process; GO:0030031 cell projection assembly; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0030182 neuron differentiation; GO:0007018 microtubule-based movement; GO:0070727 cellular macromolecule localization; GO:0044767 single-organism developmental process; GO:0006996 organelle organization; GO:0006928 movement of cell or subcellular component; GO:0060119 inner ear receptor cell development; GO:0007423 sensory organ development; GO:0051179 localization; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0036126 sperm flagellum; GO:0097729 9+2 motile cilium; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0030990 intraciliary transport particle; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0005815 microtubule organizing center; GO:0015630 microtubule cytoskeleton; GO:0044441 ciliary part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0097228 sperm principal piece; GO:0030992 intraciliary transport particle B; GO:0005929 cilium; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0097542 ciliary tip; GO:0044463 cell projection part; GO:0031514 motile cilium; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005813 centrosome; GO:0097223 sperm part; GO:0005794 Golgi apparatus; GO:0043234 protein complex; GO:0097225 sperm midpiece; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0036094 small molecule binding; ","K07934",null,null,"IPR005225; IPR027417; ","Small GTP-binding protein domain; P-loop containing nucleoside triphosphate hydrolase; \r"]
["Q9BW92","Threonine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=TARS2","TARS2",81.035,3.0706,1.3,1,1,1,1.018,0.968,0.937,0.912,1.211,0.956,1.053,0.649,"mitochondria\r","GO:0065008 regulation of biological quality; GO:0006518 peptide metabolic process; GO:0010608 posttranscriptional regulation of gene expression; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0006435 threonyl-tRNA aminoacylation; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0006418 tRNA aminoacylation for protein translation; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0006412 translation; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0043043 peptide biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0016070 RNA metabolic process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006082 organic acid metabolic process; GO:0070159 mitochondrial threonyl-tRNA aminoacylation; GO:0043436 oxoacid metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0070127 tRNA aminoacylation for mitochondrial protein translation; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0044267 cellular protein metabolic process; GO:0043039 tRNA aminoacylation; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0000959 mitochondrial RNA metabolic process; GO:0006448 regulation of translational elongation; GO:0006450 regulation of translational fidelity; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0032543 mitochondrial translation; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0034248 regulation of cellular amide metabolic process; GO:0006399 tRNA metabolic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0051246 regulation of protein metabolic process; GO:0006417 regulation of translation; GO:0043038 amino acid activation; GO:0019752 carboxylic acid metabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0034660 ncRNA metabolic process; GO:0065007 biological regulation; GO:1901564 organonitrogen compound metabolic process; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds; GO:0052689 carboxylic ester hydrolase activity; GO:1901265 nucleoside phosphate binding; GO:0016875 ligase activity, forming carbon-oxygen bonds; GO:0046983 protein dimerization activity; GO:0016874 ligase activity; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0004812 aminoacyl-tRNA ligase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0004829 threonine-tRNA ligase activity; GO:0002161 aminoacyl-tRNA editing activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0042803 protein homodimerization activity; GO:0016788 hydrolase activity, acting on ester bonds; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; ","K01868","TARS; threonyl-tRNA synthetase [EC:6.1.1.3]","hsa00970 Aminoacyl-tRNA biosynthesis - Homo sapiens (human); ","IPR018163; IPR012947; IPR033728; IPR002314; IPR012676; IPR004095; IPR004154; IPR012675; IPR006195; ","\"Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain; Threonyl/alanyl tRNA synthetase, SAD; Threonine-tRNA ligase catalytic core domain; Aminoacyl-tRNA synthetase, class II (G/ P/ S/T); TGS-like; TGS; Anticodon-binding; Beta-grasp domain; Aminoacyl-tRNA synthetase, class II; \"\r"]
["Q9BWM7","Sideroflexin-3 OS=Homo sapiens OX=9606 GN=SFXN3","SFXN3",35.503,98.992,41.4,10,17,10,1.021,1.046,1.077,0.99,0.923,0.957,0.913,0.023,"cytoplasm\r","GO:0065008 regulation of biological quality; GO:0055076 transition metal ion homeostasis; GO:0034220 ion transmembrane transport; GO:0050801 ion homeostasis; GO:0098771 inorganic ion homeostasis; GO:0055072 iron ion homeostasis; GO:0051234 establishment of localization; GO:0006810 transport; GO:0055085 transmembrane transport; GO:0042592 homeostatic process; GO:0055080 cation homeostasis; GO:0006811 ion transport; GO:0055065 metal ion homeostasis; GO:0051179 localization; GO:0048878 chemical homeostasis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044429 mitochondrial part; GO:0031090 organelle membrane; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0005740 mitochondrial envelope; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0031975 envelope; GO:0043227 membrane-bounded organelle; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0022892 substrate-specific transporter activity; GO:0015075 ion transmembrane transporter activity; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; GO:0022891 substrate-specific transmembrane transporter activity; "]
["Q9BX66","Sorbin and SH3 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SORBS1","SORBS1",142.51,63.676,13.2,13,14,13,1.088,0.993,1.095,0.957,0.917,0.933,0.884,0.0224,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0032885 regulation of polysaccharide biosynthetic process; GO:0007166 cell surface receptor signaling pathway; GO:0009891 positive regulation of biosynthetic process; GO:0030038 contractile actin filament bundle assembly; GO:0019216 regulation of lipid metabolic process; GO:0022610 biological adhesion; GO:1903729 regulation of plasma membrane organization; GO:0030036 actin cytoskeleton organization; GO:0032879 regulation of localization; GO:0007160 cell-matrix adhesion; GO:0034332 adherens junction organization; GO:0015758 glucose transport; GO:0007155 cell adhesion; GO:0009719 response to endogenous stimulus; GO:1901652 response to peptide; GO:0046324 regulation of glucose import; GO:0046889 positive regulation of lipid biosynthetic process; GO:0044765 single-organism transport; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0048041 focal adhesion assembly; GO:0006810 transport; GO:0010243 response to organonitrogen compound; GO:0008645 hexose transport; GO:0048583 regulation of response to stimulus; GO:0046890 regulation of lipid biosynthetic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:1901698 response to nitrogen compound; GO:0032869 cellular response to insulin stimulus; GO:0010604 positive regulation of macromolecule metabolic process; GO:0097435 supramolecular fiber organization; GO:0043149 stress fiber assembly; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0043255 regulation of carbohydrate biosynthetic process; GO:0015749 monosaccharide transport; GO:1903076 regulation of protein localization to plasma membrane; GO:1901700 response to oxygen-containing compound; GO:0010906 regulation of glucose metabolic process; GO:1903078 positive regulation of protein localization to plasma membrane; GO:1905477 positive regulation of protein localization to membrane; GO:0060341 regulation of cellular localization; GO:0010962 regulation of glucan biosynthetic process; GO:1902578 single-organism localization; GO:0009889 regulation of biosynthetic process; GO:0032880 regulation of protein localization; GO:0090003 regulation of establishment of protein localization to plasma membrane; GO:0007010 cytoskeleton organization; GO:0009966 regulation of signal transduction; GO:1904377 positive regulation of protein localization to cell periphery; GO:0071702 organic substance transport; GO:0010676 positive regulation of cellular carbohydrate metabolic process; GO:0010033 response to organic substance; GO:0006109 regulation of carbohydrate metabolic process; GO:0061572 actin filament bundle organization; GO:1904951 positive regulation of establishment of protein localization; GO:0070873 regulation of glycogen metabolic process; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0030029 actin filament-based process; GO:0005979 regulation of glycogen biosynthetic process; GO:0048584 positive regulation of response to stimulus; GO:0031328 positive regulation of cellular biosynthetic process; GO:0051179 localization; GO:1903827 regulation of cellular protein localization; GO:0045913 positive regulation of carbohydrate metabolic process; GO:0043467 regulation of generation of precursor metabolites and energy; GO:0008286 insulin receptor signaling pathway; GO:0003012 muscle system process; GO:0023051 regulation of signaling; GO:0045216 cell-cell junction organization; GO:0044699 single-organism process; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0007165 signal transduction; GO:1904375 regulation of protein localization to cell periphery; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:1901653 cellular response to peptide; GO:0022607 cellular component assembly; GO:0009893 positive regulation of metabolic process; GO:0007045 cell-substrate adherens junction assembly; GO:0010827 regulation of glucose transport; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0070887 cellular response to chemical stimulus; GO:0070875 positive regulation of glycogen metabolic process; GO:0031032 actomyosin structure organization; GO:0007044 cell-substrate junction assembly; GO:0031326 regulation of cellular biosynthetic process; GO:0010675 regulation of cellular carbohydrate metabolic process; GO:0010828 positive regulation of glucose transport; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0051050 positive regulation of transport; GO:0071417 cellular response to organonitrogen compound; GO:0010907 positive regulation of glucose metabolic process; GO:1902589 single-organism organelle organization; GO:0042221 response to chemical; GO:0032868 response to insulin; GO:0050789 regulation of biological process; GO:0043434 response to peptide hormone; GO:1901699 cellular response to nitrogen compound; GO:0032870 cellular response to hormone stimulus; GO:0019222 regulation of metabolic process; GO:0034333 adherens junction assembly; GO:0016043 cellular component organization; GO:0034329 cell junction assembly; GO:1903829 positive regulation of cellular protein localization; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0007015 actin filament organization; GO:0046326 positive regulation of glucose import; GO:0051017 actin filament bundle assembly; GO:0050896 response to stimulus; GO:0070201 regulation of establishment of protein localization; GO:0090004 positive regulation of establishment of protein localization to plasma membrane; GO:1905475 regulation of protein localization to membrane; GO:0006936 muscle contraction; GO:0023056 positive regulation of signaling; GO:0071375 cellular response to peptide hormone stimulus; GO:0008643 carbohydrate transport; GO:0045725 positive regulation of glycogen biosynthetic process; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:0003008 system process; GO:0051049 regulation of transport; GO:0010556 regulation of macromolecule biosynthetic process; GO:0032881 regulation of polysaccharide metabolic process; GO:0048518 positive regulation of biological process; GO:0045834 positive regulation of lipid metabolic process; GO:1901701 cellular response to oxygen-containing compound; GO:0034330 cell junction organization; GO:0031589 cell-substrate adhesion; GO:0071495 cellular response to endogenous stimulus; GO:0009967 positive regulation of signal transduction; GO:0051128 regulation of cellular component organization; GO:0009725 response to hormone; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0071944 cell periphery; GO:0098857 membrane microdomain; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005913 cell-cell adherens junction; GO:0005623 cell; GO:0005911 cell-cell junction; GO:0044422 organelle part; GO:0032432 actin filament bundle; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0005815 microtubule organizing center; GO:0070013 intracellular organelle lumen; GO:0005925 focal adhesion; GO:0015630 microtubule cytoskeleton; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0098589 membrane region; GO:0005912 adherens junction; GO:0001725 stress fiber; GO:0030055 cell-substrate junction; GO:0045121 membrane raft; GO:0043227 membrane-bounded organelle; GO:0042641 actomyosin; GO:0043233 organelle lumen; GO:0005924 cell-substrate adherens junction; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0031981 nuclear lumen; GO:0097517 contractile actin filament bundle; GO:0005829 cytosol; GO:0015629 actin cytoskeleton; GO:0043296 apical junction complex; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0005813 centrosome; GO:0016363 nuclear matrix; GO:0005915 zonula adherens; GO:0034399 nuclear periphery; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005070 SH3/SH2 adaptor activity; GO:0030674 protein binding, bridging; GO:0008092 cytoskeletal protein binding; GO:0035591 signaling adaptor activity; GO:0005102 receptor binding; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0003779 actin binding; GO:0005515 protein binding; GO:0060090 binding, bridging; GO:0032403 protein complex binding; GO:0005158 insulin receptor binding; ","K06086","SORBS1; sorbin and SH3 domain containing 1","hsa03320 PPAR signaling pathway - Homo sapiens (human); hsa04520 Adherens junction - Homo sapiens (human); hsa04910 Insulin signaling pathway - Homo sapiens (human); ","IPR011511; IPR001452; IPR003127; ","Variant SH3 domain; SH3 domain; SoHo domain; \r"]
["Q9BX97","Plasmalemma vesicle-associated protein OS=Homo sapiens OX=9606 GN=PLVAP","PLVAP",50.594,24.24,14.3,7,11,7,1.009,1.09,0.898,0.972,0.968,0.961,0.968,0.654,"plasma membrane\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0016310 phosphorylation; GO:0030335 positive regulation of cell migration; GO:0007166 cell surface receptor signaling pathway; GO:0071356 cellular response to tumor necrosis factor; GO:0040017 positive regulation of locomotion; GO:0071310 cellular response to organic substance; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:2000147 positive regulation of cell motility; GO:0050896 response to stimulus; GO:0071345 cellular response to cytokine stimulus; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0006468 protein phosphorylation; GO:0007154 cell communication; GO:0032879 regulation of localization; GO:2000145 regulation of cell motility; GO:0034612 response to tumor necrosis factor; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0019221 cytokine-mediated signaling pathway; GO:0009987 cellular process; GO:0070887 cellular response to chemical stimulus; GO:0023014 signal transduction by protein phosphorylation; GO:0051716 cellular response to stimulus; GO:0034097 response to cytokine; GO:0035556 intracellular signal transduction; GO:0051270 regulation of cellular component movement; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0030334 regulation of cell migration; GO:0010033 response to organic substance; GO:0051272 positive regulation of cellular component movement; GO:0002693 positive regulation of cellular extravasation; GO:0023052 signaling; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0033209 tumor necrosis factor-mediated signaling pathway; GO:0000165 MAPK cascade; GO:0042221 response to chemical; GO:0002691 regulation of cellular extravasation; GO:0050789 regulation of biological process; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0002684 positive regulation of immune system process; GO:0044260 cellular macromolecule metabolic process; GO:0002682 regulation of immune system process; GO:0006464 cellular protein modification process; GO:0002685 regulation of leukocyte migration; GO:0040012 regulation of locomotion; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:0002687 positive regulation of leukocyte migration; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0098857 membrane microdomain; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0005901 caveola; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0044459 plasma membrane part; GO:0098590 plasma membrane region; GO:0044853 plasma membrane raft; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0098589 membrane region; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0009986 cell surface; GO:0045121 membrane raft; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0042802 identical protein binding; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0046983 protein dimerization activity; ","K17309"]
["Q9BXB4","Oxysterol-binding protein-related protein 11 OS=Homo sapiens OX=9606 GN=OSBPL11","OSBPL11",83.642,11.944,3.1,2,3,2,0.913,0.878,0.828,1.157,1.024,1.195,1.289,0.0101,"nucleus\r","GO:0032502 developmental process; GO:0065008 regulation of biological quality; GO:0010889 regulation of sequestering of triglyceride; GO:0006869 lipid transport; GO:0010890 positive regulation of sequestering of triglyceride; GO:0010884 positive regulation of lipid storage; GO:0048869 cellular developmental process; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0071702 organic substance transport; GO:0010876 lipid localization; GO:0048518 positive regulation of biological process; GO:0051234 establishment of localization; GO:0006810 transport; GO:0030154 cell differentiation; GO:0050789 regulation of biological process; GO:0010883 regulation of lipid storage; GO:1902578 single-organism localization; GO:0044767 single-organism developmental process; GO:0032879 regulation of localization; GO:0045444 fat cell differentiation; GO:0033036 macromolecule localization; GO:0051179 localization; GO:0009987 cellular process; GO:0044765 single-organism transport; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0031902 late endosome membrane; GO:0044464 cell part; GO:0005622 intracellular; GO:0098805 whole membrane; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0010008 endosome membrane; GO:0005770 late endosome; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0008289 lipid binding; GO:0005488 binding; ","K20465",null,null,"IPR011993; IPR001849; ","PH domain-like; Pleckstrin homology domain; \r"]
["Q9BXK5","Bcl-2-like protein 13 OS=Homo sapiens OX=9606 GN=BCL2L13","BCL2L13",52.723,12.935,7,3,3,3,0.992,0.992,1.041,1.019,1.001,0.965,0.987,0.589,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0010941 regulation of cell death; GO:0032270 positive regulation of cellular protein metabolic process; GO:2001056 positive regulation of cysteine-type endopeptidase activity; GO:0060255 regulation of macromolecule metabolic process; GO:0043067 regulation of programmed cell death; GO:0043065 positive regulation of apoptotic process; GO:0044699 single-organism process; GO:0045862 positive regulation of proteolysis; GO:0009893 positive regulation of metabolic process; GO:0051345 positive regulation of hydrolase activity; GO:0044093 positive regulation of molecular function; GO:0006915 apoptotic process; GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0009987 cellular process; GO:0052548 regulation of endopeptidase activity; GO:0010950 positive regulation of endopeptidase activity; GO:2000116 regulation of cysteine-type endopeptidase activity; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0030162 regulation of proteolysis; GO:0031323 regulation of cellular metabolic process; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0010942 positive regulation of cell death; GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0051247 positive regulation of protein metabolic process; GO:0051336 regulation of hydrolase activity; GO:0008219 cell death; GO:0050790 regulation of catalytic activity; GO:0051246 regulation of protein metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0012501 programmed cell death; GO:0052547 regulation of peptidase activity; GO:0010952 positive regulation of peptidase activity; GO:0042981 regulation of apoptotic process; GO:0043068 positive regulation of programmed cell death; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044429 mitochondrial part; GO:0031090 organelle membrane; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0005740 mitochondrial envelope; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0031975 envelope; GO:0043227 membrane-bounded organelle; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0061134 peptidase regulator activity; GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process; GO:0016504 peptidase activator activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0016505 peptidase activator activity involved in apoptotic process; GO:0008047 enzyme activator activity; ","K15485","BCL2L13; Bcl-2-like protein 13","hsa05134 Legionellosis - Homo sapiens (human); hsa04137 Mitophagy - animal - Homo sapiens (human); "]
["Q9BXN1","Asporin OS=Homo sapiens OX=9606 GN=ASPN","ASPN",43.417,102.03,36.6,13,26,13,1.174,1.19,1.18,0.848,0.838,0.809,0.704,1.91E-5,"extracellular\r","GO:0044700 single organism signaling; GO:0051093 negative regulation of developmental process; GO:0009968 negative regulation of signal transduction; GO:0007166 cell surface receptor signaling pathway; GO:0023051 regulation of signaling; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:1903845 negative regulation of cellular response to transforming growth factor beta stimulus; GO:0071345 cellular response to cytokine stimulus; GO:0070167 regulation of biomineral tissue development; GO:0031400 negative regulation of protein modification process; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0033673 negative regulation of kinase activity; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0009888 tissue development; GO:0034097 response to cytokine; GO:0080090 regulation of primary metabolic process; GO:0001503 ossification; GO:0090287 regulation of cellular response to growth factor stimulus; GO:0070168 negative regulation of biomineral tissue development; GO:0051348 negative regulation of transferase activity; GO:0023052 signaling; GO:0031323 regulation of cellular metabolic process; GO:0043086 negative regulation of catalytic activity; GO:0010605 negative regulation of macromolecule metabolic process; GO:0032501 multicellular organismal process; GO:0042481 regulation of odontogenesis; GO:0030282 bone mineralization; GO:0048513 animal organ development; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:1902532 negative regulation of intracellular signal transduction; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0048583 regulation of response to stimulus; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0006469 negative regulation of protein kinase activity; GO:0044092 negative regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0048856 anatomical structure development; GO:0043549 regulation of kinase activity; GO:2000026 regulation of multicellular organismal development; GO:0046425 regulation of JAK-STAT cascade; GO:0050794 regulation of cellular process; GO:0045859 regulation of protein kinase activity; GO:0044707 single-multicellular organism process; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0017015 regulation of transforming growth factor beta receptor signaling pathway; GO:0031399 regulation of protein modification process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0051239 regulation of multicellular organismal process; GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0070170 regulation of tooth mineralization; GO:0023057 negative regulation of signaling; GO:2000027 regulation of organ morphogenesis; GO:0046426 negative regulation of JAK-STAT cascade; GO:0010648 negative regulation of cell communication; GO:1904893 negative regulation of STAT cascade; GO:0042326 negative regulation of phosphorylation; GO:0090288 negative regulation of cellular response to growth factor stimulus; GO:0051338 regulation of transferase activity; GO:0001933 negative regulation of protein phosphorylation; GO:0031214 biomineral tissue development; GO:0007275 multicellular organism development; GO:0019221 cytokine-mediated signaling pathway; GO:0009987 cellular process; GO:0009966 regulation of signal transduction; GO:1904892 regulation of STAT cascade; GO:1902531 regulation of intracellular signal transduction; GO:0048731 system development; GO:0001932 regulation of protein phosphorylation; GO:0010033 response to organic substance; GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway; GO:0070171 negative regulation of tooth mineralization; GO:0048585 negative regulation of response to stimulus; GO:0009892 negative regulation of metabolic process; GO:1903844 regulation of cellular response to transforming growth factor beta stimulus; GO:0042483 negative regulation of odontogenesis; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0010563 negative regulation of phosphorus metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0050793 regulation of developmental process; GO:0045936 negative regulation of phosphate metabolic process; GO:0065007 biological regulation; ","GO:0031012 extracellular matrix; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0005578 proteinaceous extracellular matrix; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; ","GO:0043167 ion binding; GO:0044877 macromolecular complex binding; GO:0005515 protein binding; GO:0004860 protein kinase inhibitor activity; GO:0019207 kinase regulator activity; GO:0019887 protein kinase regulator activity; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0030234 enzyme regulator activity; GO:0019210 kinase inhibitor activity; GO:0005488 binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005518 collagen binding; GO:0005509 calcium ion binding; GO:0032403 protein complex binding; ","K08120",null,null,"IPR000372; IPR032675; ","\"Leucine-rich repeat N-terminal domain; Leucine-rich repeat domain, L domain-like; \"\r"]
["Q9BXR0","Queuine tRNA-ribosyltransferase catalytic subunit 1 OS=Homo sapiens OX=9606 GN=QTRT1","QTRT1",44.047,2.1115,3.2,1,1,1,0.982,0.97,0.863,1.187,0.869,1.137,1.134,0.326,"cytoplasm\r","GO:0009116 nucleoside metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0044699 single-organism process; GO:0009163 nucleoside biosynthetic process; GO:0009058 biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0009451 RNA modification; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0101030 tRNA-guanine transglycosylation; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0006400 tRNA modification; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009119 ribonucleoside metabolic process; GO:0009987 cellular process; GO:0034470 ncRNA processing; GO:0006396 RNA processing; GO:0018130 heterocycle biosynthetic process; GO:0044711 single-organism biosynthetic process; GO:0044281 small molecule metabolic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0046116 queuosine metabolic process; GO:0042455 ribonucleoside biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0016070 RNA metabolic process; GO:0006399 tRNA metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0090304 nucleic acid metabolic process; GO:0044710 single-organism metabolic process; GO:1901659 glycosyl compound biosynthetic process; GO:0008033 tRNA processing; GO:0008616 queuosine biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:1901657 glycosyl compound metabolic process; GO:0043412 macromolecule modification; GO:0034660 ncRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0019867 outer membrane; GO:0044429 mitochondrial part; GO:0098588 bounding membrane of organelle; GO:0031090 organelle membrane; GO:0005741 mitochondrial outer membrane; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005740 mitochondrial envelope; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:0031975 envelope; GO:0098805 whole membrane; GO:0031968 organelle outer membrane; GO:0043227 membrane-bounded organelle; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0016763 transferase activity, transferring pentosyl groups; GO:0042802 identical protein binding; GO:0046982 protein heterodimerization activity; GO:0003824 catalytic activity; GO:0042803 protein homodimerization activity; GO:0008479 queuine tRNA-ribosyltransferase activity; GO:0005488 binding; GO:0043167 ion binding; GO:0046983 protein dimerization activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0016757 transferase activity, transferring glycosyl groups; GO:0005515 protein binding; GO:0016740 transferase activity; ","K00773"]
["Q9BXW7","Haloacid dehalogenase-like hydrolase domain-containing 5 OS=Homo sapiens OX=9606 GN=HDHD5","HDHD5",46.321,8.8868,11.1,3,3,3,0.902,0.737,0.894,1.162,1.16,1.13,1.363,0.0421,"mitochondria\r","GO:0046486 glycerolipid metabolic process; GO:0044711 single-organism biosynthetic process; GO:0008654 phospholipid biosynthetic process; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044255 cellular lipid metabolic process; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:1901576 organic substance biosynthetic process; GO:0006796 phosphate-containing compound metabolic process; GO:0044249 cellular biosynthetic process; GO:0071704 organic substance metabolic process; GO:0008610 lipid biosynthetic process; GO:0045017 glycerolipid biosynthetic process; GO:0090407 organophosphate biosynthetic process; GO:0008152 metabolic process; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0046474 glycerophospholipid biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0006650 glycerophospholipid metabolic process; GO:0006644 phospholipid metabolic process; GO:0009987 cellular process; GO:0006629 lipid metabolic process; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044444 cytoplasmic part; ",{"$nulls":4},"IPR023214; ","HAD-like domain; \r"]
["Q9BY43","Charged multivesicular body protein 4a OS=Homo sapiens OX=9606 GN=CHMP4A","CHMP4A",25.098,18.971,23.4,5,6,5,0.997,0.928,0.845,1.02,1.073,1.136,1.166,0.0537,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0010941 regulation of cell death; GO:0010256 endomembrane system organization; GO:0072594 establishment of protein localization to organelle; GO:1902902 negative regulation of autophagosome assembly; GO:0007067 mitotic nuclear division; GO:0051129 negative regulation of cellular component organization; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:1902116 negative regulation of organelle assembly; GO:0006914 autophagy; GO:0044237 cellular metabolic process; GO:1902115 regulation of organelle assembly; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0008152 metabolic process; GO:0050000 chromosome localization; GO:0000819 sister chromatid segregation; GO:0051649 establishment of localization in cell; GO:0070972 protein localization to endoplasmic reticulum; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0036258 multivesicular body assembly; GO:0033365 protein localization to organelle; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0044419 interspecies interaction between organisms; GO:0016236 macroautophagy; GO:0000278 mitotic cell cycle; GO:0007059 chromosome segregation; GO:0044088 regulation of vacuole organization; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0071822 protein complex subunit organization; GO:0072657 protein localization to membrane; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0039702 viral budding via host ESCRT complex; GO:0044763 single-organism cellular process; GO:0045047 protein targeting to ER; GO:0036257 multivesicular body organization; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0007009 plasma membrane organization; GO:0031323 regulation of cellular metabolic process; GO:0010506 regulation of autophagy; GO:0051704 multi-organism process; GO:0016197 endosomal transport; GO:0006810 transport; GO:0016241 regulation of macroautophagy; GO:1902589 single-organism organelle organization; GO:2000785 regulation of autophagosome assembly; GO:0010639 negative regulation of organelle organization; GO:0050789 regulation of biological process; GO:0051258 protein polymerization; GO:0019222 regulation of metabolic process; GO:0051301 cell division; GO:0010507 negative regulation of autophagy; GO:0006620 posttranslational protein targeting to membrane; GO:0070271 protein complex biogenesis; GO:0060548 negative regulation of cell death; GO:0097320 plasma membrane tubulation; GO:0016242 negative regulation of macroautophagy; GO:0050794 regulation of cellular process; GO:0051640 organelle localization; GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0006997 nucleus organization; GO:0019068 virion assembly; GO:0051260 protein homooligomerization; GO:0019058 viral life cycle; GO:0048285 organelle fission; GO:0010324 membrane invagination; GO:1902592 multi-organism membrane budding; GO:0000920 cell separation after cytokinesis; GO:0044087 regulation of cellular component biogenesis; GO:0007080 mitotic metaphase plate congression; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0051310 metaphase plate congression; GO:1903047 mitotic cell cycle process; GO:0051259 protein oligomerization; GO:0070925 organelle assembly; GO:0016032 viral process; GO:0006886 intracellular protein transport; GO:0044248 cellular catabolic process; GO:0009895 negative regulation of catabolic process; GO:0034613 cellular protein localization; GO:0090150 establishment of protein localization to membrane; GO:0009987 cellular process; GO:1901214 regulation of neuron death; GO:0006461 protein complex assembly; GO:0043623 cellular protein complex assembly; GO:1901215 negative regulation of neuron death; GO:0034622 cellular macromolecular complex assembly; GO:0044803 multi-organism membrane organization; GO:0051303 establishment of chromosome localization; GO:0016192 vesicle-mediated transport; GO:0044802 single-organism membrane organization; GO:0016050 vesicle organization; GO:0033043 regulation of organelle organization; GO:0000070 mitotic sister chromatid segregation; GO:0071702 organic substance transport; GO:0051656 establishment of organelle localization; GO:1902590 multi-organism organelle organization; GO:0009892 negative regulation of metabolic process; GO:0051641 cellular localization; GO:0043933 macromolecular complex subunit organization; GO:0045184 establishment of protein localization; GO:0031330 negative regulation of cellular catabolic process; GO:0070727 cellular macromolecule localization; GO:0051276 chromosome organization; GO:0046755 viral budding; GO:0007034 vacuolar transport; GO:0098813 nuclear chromosome segregation; GO:0006996 organelle organization; GO:0006900 membrane budding; GO:0061024 membrane organization; GO:0000280 nuclear division; GO:0022402 cell cycle process; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0009056 catabolic process; GO:0007032 endosome organization; GO:0007049 cell cycle; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0098796 membrane protein complex; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0009898 cytoplasmic side of plasma membrane; GO:0098562 cytoplasmic side of membrane; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0036452 ESCRT complex; GO:0031902 late endosome membrane; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0000815 ESCRT III complex; GO:0098552 side of membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0010008 endosome membrane; GO:0005770 late endosome; GO:0098588 bounding membrane of organelle; GO:0048475 coated membrane; GO:0044446 intracellular organelle part; GO:0030496 midbody; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0030117 membrane coat; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0042802 identical protein binding; GO:0051117 ATPase binding; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0046983 protein dimerization activity; GO:0008289 lipid binding; GO:0005515 protein binding; GO:0019899 enzyme binding; ","K12194","CHMP4; charged multivesicular body protein 4","hsa04144 Endocytosis - Homo sapiens (human); hsa04217 Necroptosis - Homo sapiens (human); "]
["Q9BYG4","Partitioning defective 6 homolog gamma OS=Homo sapiens OX=9606 GN=PARD6G","PARD6G",40.883,2.8251,2.4,1,2,1,0.97,0.788,1.088,0.959,1.121,1.065,1.105,0.367,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0043297 apical junction assembly; GO:0016043 cellular component organization; GO:0034329 cell junction assembly; GO:0007043 cell-cell junction assembly; GO:0044763 single-organism cellular process; GO:0045216 cell-cell junction organization; GO:0044699 single-organism process; GO:0034330 cell junction organization; GO:0022607 cellular component assembly; GO:0070830 bicellular tight junction assembly; GO:0051301 cell division; GO:0009987 cellular process; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005911 cell-cell junction; GO:0005829 cytosol; GO:0005623 cell; GO:0005923 bicellular tight junction; GO:0043296 apical junction complex; GO:0005886 plasma membrane; GO:0070160 occluding junction; GO:0005622 intracellular; GO:0044464 cell part; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ","K06093","PARD6; partitioning defective protein 6","hsa04390 Hippo signaling pathway - Homo sapiens (human); hsa04015 Rap1 signaling pathway - Homo sapiens (human); hsa04144 Endocytosis - Homo sapiens (human); hsa04530 Tight junction - Homo sapiens (human); hsa04360 Axon guidance - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); ","IPR000270; IPR001478; ","PB1 domain; PDZ domain; \r"]
["Q9BYN7","Zinc finger protein 341 OS=Homo sapiens OX=9606 GN=ZNF341","ZNF341",92.727,1.8768,0.9,1,1,1,1.047,0.998,0.955,1.013,1.014,0.983,1.003,0.897,"nucleus\r","GO:0050794 regulation of cellular process; GO:0006725 cellular aromatic compound metabolic process; GO:0097659 nucleic acid-templated transcription; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0006355 regulation of transcription, DNA-templated; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0044238 primary metabolic process; GO:0051252 regulation of RNA metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0034645 cellular macromolecule biosynthetic process; GO:0090304 nucleic acid metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006351 transcription, DNA-templated; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0010467 gene expression; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0065007 biological regulation; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003677 DNA binding; GO:0005488 binding; GO:0001071 nucleic acid binding transcription factor activity; GO:0043167 ion binding; GO:0003676 nucleic acid binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0003700 transcription factor activity, sequence-specific DNA binding; ",{"$nulls":3},"IPR015880; IPR013083; IPR007087; IPR013087; ","\"Zinc finger, C2H2-like; Zinc finger, RING/FYVE/PHD-type; Zinc finger, C2H2; Zinc finger C2H2-type/integrase DNA-binding domain; \"\r"]
["Q9BZ29","Dedicator of cytokinesis protein 9 OS=Homo sapiens OX=9606 GN=DOCK9","DOCK9",236.44,4.252,0.6,1,1,1,0.98,0.982,1.163,0.917,0.997,0.967,0.922,0.272,"nucleus\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0051716 cellular response to stimulus; GO:0044707 single-multicellular organism process; GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0050878 regulation of body fluid levels; GO:0006950 response to stress; GO:0035556 intracellular signal transduction; GO:0043547 positive regulation of GTPase activity; GO:0044699 single-organism process; GO:0007264 small GTPase mediated signal transduction; GO:0023052 signaling; GO:0050896 response to stimulus; GO:0032501 multicellular organismal process; GO:0007599 hemostasis; GO:0043085 positive regulation of catalytic activity; GO:0009611 response to wounding; GO:0007165 signal transduction; GO:0050789 regulation of biological process; GO:0007154 cell communication; GO:0042060 wound healing; GO:0051336 regulation of hydrolase activity; GO:0051345 positive regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0044093 positive regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0065009 regulation of molecular function; GO:0050817 coagulation; GO:0009987 cellular process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005622 intracellular; GO:0044464 cell part; GO:0005737 cytoplasm; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0044444 cytoplasmic part; ","GO:0050839 cell adhesion molecule binding; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0005085 guanyl-nucleotide exchange factor activity; GO:0005488 binding; GO:0045296 cadherin binding; ",{"$nulls":3},"IPR021816; IPR010703; IPR027357; IPR011993; IPR027007; IPR016024; IPR001849; ","\"Dedicator of cytokinesis C/D, N-terminal; Dedicator of cytokinesis, C-terminal; DHR-2 domain; PH domain-like; DHR-1 domain; Armadillo-type fold; Pleckstrin homology domain; \"\r"]
["Q9BZF1","Oxysterol-binding protein-related protein 8 OS=Homo sapiens OX=9606 GN=OSBPL8","OSBPL8",101.19,15.663,8,5,5,5,0.931,0.969,1.065,1.01,0.954,1.008,1.002,0.939,"cytoplasm\r","GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0051896 regulation of protein kinase B signaling; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0033365 protein localization to organelle; GO:0051347 positive regulation of transferase activity; GO:0008104 protein localization; GO:2001273 regulation of glucose import in response to insulin stimulus; GO:0046324 regulation of glucose import; GO:0044765 single-organism transport; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0006869 lipid transport; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:2000146 negative regulation of cell motility; GO:0031323 regulation of cellular metabolic process; GO:0006810 transport; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0010604 positive regulation of macromolecule metabolic process; GO:0050794 regulation of cellular process; GO:0010891 negative regulation of sequestering of triglyceride; GO:0010889 regulation of sequestering of triglyceride; GO:0031399 regulation of protein modification process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0036150 phosphatidylserine acyl-chain remodeling; GO:1902578 single-organism localization; GO:0032147 activation of protein kinase activity; GO:2000145 regulation of cell motility; GO:0051338 regulation of transferase activity; GO:0034613 cellular protein localization; GO:0009966 regulation of signal transduction; GO:1902531 regulation of intracellular signal transduction; GO:0051270 regulation of cellular component movement; GO:0030334 regulation of cell migration; GO:0071702 organic substance transport; GO:0010876 lipid localization; GO:0015914 phospholipid transport; GO:0044238 primary metabolic process; GO:0051247 positive regulation of protein metabolic process; GO:0010883 regulation of lipid storage; GO:0030336 negative regulation of cell migration; GO:0006793 phosphorus metabolic process; GO:0006811 ion transport; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0031325 positive regulation of cellular metabolic process; GO:0019637 organophosphate metabolic process; GO:0006644 phospholipid metabolic process; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:1901564 organonitrogen compound metabolic process; GO:0010256 endomembrane system organization; GO:0046486 glycerolipid metabolic process; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0090204 protein localization to nuclear pore; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0040013 negative regulation of locomotion; GO:0010646 regulation of cell communication; GO:0009893 positive regulation of metabolic process; GO:0006650 glycerophospholipid metabolic process; GO:0010827 regulation of glucose transport; GO:0033674 positive regulation of kinase activity; GO:0033036 macromolecule localization; GO:0006629 lipid metabolic process; GO:0032502 developmental process; GO:0045937 positive regulation of phosphate metabolic process; GO:0010828 positive regulation of glucose transport; GO:0048522 positive regulation of cellular process; GO:0051050 positive regulation of transport; GO:0015748 organophosphate ester transport; GO:0006658 phosphatidylserine metabolic process; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0045444 fat cell differentiation; GO:0019220 regulation of phosphate metabolic process; GO:0043549 regulation of kinase activity; GO:0051271 negative regulation of cellular component movement; GO:0045859 regulation of protein kinase activity; GO:0006997 nucleus organization; GO:0016043 cellular component organization; GO:0060255 regulation of macromolecule metabolic process; GO:0046326 positive regulation of glucose import; GO:1900076 regulation of cellular response to insulin stimulus; GO:0006998 nuclear envelope organization; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0006575 cellular modified amino acid metabolic process; GO:0023056 positive regulation of signaling; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:0010888 negative regulation of lipid storage; GO:2001275 positive regulation of glucose import in response to insulin stimulus; GO:0032148 activation of protein kinase B activity; GO:0051897 positive regulation of protein kinase B signaling; GO:0046628 positive regulation of insulin receptor signaling pathway; GO:0051049 regulation of transport; GO:0001932 regulation of protein phosphorylation; GO:0031401 positive regulation of protein modification process; GO:0044802 single-organism membrane organization; GO:0006807 nitrogen compound metabolic process; GO:0045860 positive regulation of protein kinase activity; GO:0001934 positive regulation of protein phosphorylation; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:1900078 positive regulation of cellular response to insulin stimulus; GO:0051641 cellular localization; GO:0006820 anion transport; GO:0070727 cellular macromolecule localization; GO:0015711 organic anion transport; GO:0046626 regulation of insulin receptor signaling pathway; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0009967 positive regulation of signal transduction; GO:0040012 regulation of locomotion; GO:0034504 protein localization to nucleus; GO:0090435 protein localization to nuclear envelope; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0005938 cell cortex; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0099568 cytoplasmic region; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031965 nuclear membrane; GO:0098827 endoplasmic reticulum subcompartment; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043229 intracellular organelle; GO:0005635 nuclear envelope; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0032541 cortical endoplasmic reticulum; GO:0005829 cytosol; GO:0016021 integral component of membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0071782 endoplasmic reticulum tubular network; GO:0005634 nucleus; GO:0044432 endoplasmic reticulum part; GO:0044448 cell cortex part; GO:0031975 envelope; GO:0044444 cytoplasmic part; GO:0031984 organelle subcompartment; GO:0044428 nuclear part; ","GO:1901981 phosphatidylinositol phosphate binding; GO:0015485 cholesterol binding; GO:0032934 sterol binding; GO:0043167 ion binding; GO:0005319 lipid transporter activity; GO:0022892 substrate-specific transporter activity; GO:0001786 phosphatidylserine binding; GO:0005496 steroid binding; GO:0097159 organic cyclic compound binding; GO:0072341 modified amino acid binding; GO:0043178 alcohol binding; GO:0005488 binding; GO:0005543 phospholipid binding; GO:0035091 phosphatidylinositol binding; GO:0008289 lipid binding; GO:0043168 anion binding; GO:0070273 phosphatidylinositol-4-phosphate binding; GO:0005548 phospholipid transporter activity; GO:0005215 transporter activity; GO:0036094 small molecule binding; ","K20464","OSBPL5; oxysterol-binding protein-related protein 5","hsa04979 Cholesterol metabolism - Homo sapiens (human); ","IPR011993; IPR001849; ","PH domain-like; Pleckstrin homology domain; \r"]
["Q9BZF9","Uveal autoantigen with coiled-coil domains and ankyrin repeats OS=Homo sapiens OX=9606 GN=UACA","UACA",162.5,27.165,9.1,12,13,12,1.032,1.039,1.057,0.895,0.985,0.992,0.918,0.0635,"nucleus\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0051716 cellular response to stimulus; GO:1902531 regulation of intracellular signal transduction; GO:0097190 apoptotic signaling pathway; GO:1901222 regulation of NIK/NF-kappaB signaling; GO:0023051 regulation of signaling; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0023052 signaling; GO:0050896 response to stimulus; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0050789 regulation of biological process; GO:0007154 cell communication; GO:0008219 cell death; GO:0048583 regulation of response to stimulus; GO:0006915 apoptotic process; GO:0012501 programmed cell death; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0043228 non-membrane-bounded organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005856 cytoskeleton; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR000727; IPR020683; ","Target SNARE coiled-coil homology domain; Ankyrin repeat-containing domain; \r"]
["Q9BZK3","Putative nascent polypeptide-associated complex subunit alpha-like protein OS=Homo sapiens OX=9606 GN=NACAP1","NACAP1",23.306,6.2723,7,1,2,1,0.903,0.986,0.929,1.064,1.064,1.055,1.13,0.0424,"cytoplasm\r",{"$nulls":6},"IPR002715; ","Nascent polypeptide-associated complex NAC domain; \r"]
["Q9BZV1","UBX domain-containing protein 6 OS=Homo sapiens OX=9606 GN=UBXN6","UBXN6",49.753,4.8724,5.2,2,2,2,0.895,0.941,1.083,1.006,1.018,1.057,1.055,0.388,"cytoplasm\r",null,"GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005856 cytoskeleton; GO:0005634 nucleus; GO:0005815 microtubule organizing center; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0005515 protein binding; GO:0005488 binding; ","K14011","UBXN6; UBX domain-containing protein 6","hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); ","IPR029071; IPR001012; IPR018997; ","Ubiquitin-related domain; UBX domain; PUB domain; \r"]
["Q9C035","Tripartite motif-containing protein 5 OS=Homo sapiens OX=9606 GN=TRIM5","TRIM5",56.338,3.9165,3.7,2,2,2,1.109,1.089,0.964,0.932,0.908,1.015,0.903,0.141,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0032270 positive regulation of cellular protein metabolic process; GO:0007166 cell surface receptor signaling pathway; GO:0098542 defense response to other organism; GO:0006914 autophagy; GO:0031347 regulation of defense response; GO:0071345 cellular response to cytokine stimulus; GO:0044237 cellular metabolic process; GO:0009607 response to biotic stimulus; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0065003 macromolecular complex assembly; GO:0032879 regulation of localization; GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling; GO:0044093 positive regulation of molecular function; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:0046597 negative regulation of viral entry into host cell; GO:0002758 innate immune response-activating signal transduction; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0031323 regulation of cellular metabolic process; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:1903506 regulation of nucleic acid-templated transcription; GO:0051092 positive regulation of NF-kappaB transcription factor activity; GO:0051090 regulation of sequence-specific DNA binding transcription factor activity; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0002682 regulation of immune system process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:1903901 negative regulation of viral life cycle; GO:0051259 protein oligomerization; GO:0000209 protein polyubiquitination; GO:0031349 positive regulation of defense response; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway; GO:0044248 cellular catabolic process; GO:0032880 regulation of protein localization; GO:0009966 regulation of signal transduction; GO:0050778 positive regulation of immune response; GO:0006461 protein complex assembly; GO:0002253 activation of immune response; GO:1902531 regulation of intracellular signal transduction; GO:0016567 protein ubiquitination; GO:0006950 response to stress; GO:0043900 regulation of multi-organism process; GO:0032101 regulation of response to external stimulus; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1902186 regulation of viral release from host cell; GO:0051247 positive regulation of protein metabolic process; GO:0032446 protein modification by small protein conjugation; GO:0031325 positive regulation of cellular metabolic process; GO:0043412 macromolecule modification; GO:0048584 positive regulation of response to stimulus; GO:0006955 immune response; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0071346 cellular response to interferon-gamma; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0060333 interferon-gamma-mediated signaling pathway; GO:0040013 negative regulation of locomotion; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0045088 regulation of innate immune response; GO:0022607 cellular component assembly; GO:0002221 pattern recognition receptor signaling pathway; GO:0046596 regulation of viral entry into host cell; GO:0070887 cellular response to chemical stimulus; GO:0048525 negative regulation of viral process; GO:0010468 regulation of gene expression; GO:0045937 positive regulation of phosphate metabolic process; GO:0071822 protein complex subunit organization; GO:0034097 response to cytokine; GO:0031326 regulation of cellular biosynthetic process; GO:0048522 positive regulation of cellular process; GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity; GO:0070647 protein modification by small protein conjugation or removal; GO:0023052 signaling; GO:0002764 immune response-regulating signaling pathway; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0051607 defense response to virus; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0006952 defense response; GO:0036211 protein modification process; GO:0070271 protein complex biogenesis; GO:0009615 response to virus; GO:0070534 protein K63-linked ubiquitination; GO:0016043 cellular component organization; GO:0002218 activation of innate immune response; GO:0002831 regulation of response to biotic stimulus; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0045087 innate immune response; GO:0071704 organic substance metabolic process; GO:0043408 regulation of MAPK cascade; GO:0023056 positive regulation of signaling; GO:0016032 viral process; GO:0002757 immune response-activating signal transduction; GO:0010647 positive regulation of cell communication; GO:0019221 cytokine-mediated signaling pathway; GO:0009987 cellular process; GO:0045089 positive regulation of innate immune response; GO:0070206 protein trimerization; GO:0006355 regulation of transcription, DNA-templated; GO:0001932 regulation of protein phosphorylation; GO:0050792 regulation of viral process; GO:0031401 positive regulation of protein modification process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0034341 response to interferon-gamma; GO:0001934 positive regulation of protein phosphorylation; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0043901 negative regulation of multi-organism process; GO:1902187 negative regulation of viral release from host cell; GO:0051246 regulation of protein metabolic process; GO:0002684 positive regulation of immune system process; GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling; GO:0009967 positive regulation of signal transduction; GO:0043410 positive regulation of MAPK cascade; GO:0040012 regulation of locomotion; GO:1903900 regulation of viral life cycle; GO:0009056 catabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0000932 P-body; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0043228 non-membrane-bounded organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:0035770 ribonucleoprotein granule; GO:1990904 ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0030529 intracellular ribonucleoprotein complex; GO:0044444 cytoplasmic part; ","GO:0038023 signaling receptor activity; GO:0030674 protein binding, bridging; GO:0019787 ubiquitin-like protein transferase activity; GO:0046983 protein dimerization activity; GO:0043167 ion binding; GO:0019901 protein kinase binding; GO:0005515 protein binding; GO:0008270 zinc ion binding; GO:0019900 kinase binding; GO:0004871 signal transducer activity; GO:0060089 molecular transducer activity; GO:0042802 identical protein binding; GO:0004872 receptor activity; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0004842 ubiquitin-protein transferase activity; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0060090 binding, bridging; GO:0038187 pattern recognition receptor activity; GO:0016740 transferase activity; GO:0019899 enzyme binding; GO:0008329 signaling pattern recognition receptor activity; ","K10648",null,null,"IPR001841; IPR001870; IPR013320; IPR000315; IPR003877; IPR027370; IPR013083; IPR003879; ","\"Zinc finger, RING-type; B30.2/SPRY domain; Concanavalin A-like lectin/glucanase domain; B-box-type zinc finger; SPRY domain; RING-type zinc-finger, LisH dimerisation motif; Zinc finger, RING/FYVE/PHD-type; Butyrophylin-like; \"\r"]
["Q9C0C2","182 kDa tankyrase-1-binding protein OS=Homo sapiens OX=9606 GN=TNKS1BP1","TNKS1BP1",181.79,277.02,32.6,42,53,42,0.999,1.01,0.984,0.998,0.993,1.019,1.006,0.632,"nucleus\r","GO:0044700 single organism signaling; GO:1902807 negative regulation of cell cycle G1/S phase transition; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0072431 signal transduction involved in mitotic G1 DNA damage checkpoint; GO:1902403 signal transduction involved in mitotic DNA integrity checkpoint; GO:0008152 metabolic process; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0010800 positive regulation of peptidyl-threonine phosphorylation; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0043170 macromolecule metabolic process; GO:0090068 positive regulation of cell cycle process; GO:0033138 positive regulation of peptidyl-serine phosphorylation; GO:0000278 mitotic cell cycle; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0051174 regulation of phosphorus metabolic process; GO:0044773 mitotic DNA damage checkpoint; GO:0071214 cellular response to abiotic stimulus; GO:0080090 regulation of primary metabolic process; GO:2000134 negative regulation of G1/S transition of mitotic cell cycle; GO:0044763 single-organism cellular process; GO:0031323 regulation of cellular metabolic process; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0010948 negative regulation of cell cycle process; GO:0072413 signal transduction involved in mitotic cell cycle checkpoint; GO:1902400 intracellular signal transduction involved in G1 DNA damage checkpoint; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0032200 telomere organization; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0007346 regulation of mitotic cell cycle; GO:0009628 response to abiotic stimulus; GO:0006259 DNA metabolic process; GO:0031399 regulation of protein modification process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0060249 anatomical structure homeostasis; GO:0030330 DNA damage response, signal transduction by p53 class mediator; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1902402 signal transduction involved in mitotic DNA damage checkpoint; GO:1901987 regulation of cell cycle phase transition; GO:0044819 mitotic G1/S transition checkpoint; GO:0007093 mitotic cell cycle checkpoint; GO:0044248 cellular catabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0045787 positive regulation of cell cycle; GO:0006950 response to stress; GO:0033135 regulation of peptidyl-serine phosphorylation; GO:0072331 signal transduction by p53 class mediator; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0006974 cellular response to DNA damage stimulus; GO:0051247 positive regulation of protein metabolic process; GO:0051276 chromosome organization; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0000723 telomere maintenance; GO:2000045 regulation of G1/S transition of mitotic cell cycle; GO:0031954 positive regulation of protein autophosphorylation; GO:0044783 G1 DNA damage checkpoint; GO:0044699 single-organism process; GO:0010833 telomere maintenance via telomere lengthening; GO:0009058 biosynthetic process; GO:0045930 negative regulation of mitotic cell cycle; GO:0007165 signal transduction; GO:0000077 DNA damage checkpoint; GO:0044774 mitotic DNA integrity checkpoint; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:1901991 negative regulation of mitotic cell cycle phase transition; GO:1902806 regulation of cell cycle G1/S phase transition; GO:0000075 cell cycle checkpoint; GO:1901361 organic cyclic compound catabolic process; GO:0009314 response to radiation; GO:0071479 cellular response to ionizing radiation; GO:0051726 regulation of cell cycle; GO:0031571 mitotic G1 DNA damage checkpoint; GO:0010468 regulation of gene expression; GO:0045937 positive regulation of phosphate metabolic process; GO:0031570 DNA integrity checkpoint; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0006401 RNA catabolic process; GO:0016070 RNA metabolic process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0072401 signal transduction involved in DNA integrity checkpoint; GO:0016043 cellular component organization; GO:0045786 negative regulation of cell cycle; GO:0072395 signal transduction involved in cell cycle checkpoint; GO:0006725 cellular aromatic compound metabolic process; GO:0010799 regulation of peptidyl-threonine phosphorylation; GO:1901988 negative regulation of cell cycle phase transition; GO:0060255 regulation of macromolecule metabolic process; GO:0006302 double-strand break repair; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0042770 signal transduction in response to DNA damage; GO:0034641 cellular nitrogen compound metabolic process; GO:0071897 DNA biosynthetic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0071478 cellular response to radiation; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0071156 regulation of cell cycle arrest; GO:0044265 cellular macromolecule catabolic process; GO:0072422 signal transduction involved in DNA damage checkpoint; GO:0035556 intracellular signal transduction; GO:0010629 negative regulation of gene expression; GO:0001932 regulation of protein phosphorylation; GO:0006807 nitrogen compound metabolic process; GO:0031401 positive regulation of protein modification process; GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening; GO:0031952 regulation of protein autophosphorylation; GO:0001934 positive regulation of protein phosphorylation; GO:0007004 telomere maintenance via telomerase; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0006281 DNA repair; GO:0010212 response to ionizing radiation; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0051246 regulation of protein metabolic process; GO:0009057 macromolecule catabolic process; GO:0071158 positive regulation of cell cycle arrest; GO:0022402 cell cycle process; GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0006278 RNA-dependent DNA biosynthetic process; GO:0065007 biological regulation; GO:0046700 heterocycle catabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005913 cell-cell adherens junction; GO:0005623 cell; GO:0005911 cell-cell junction; GO:0044422 organelle part; GO:0000792 heterochromatin; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044454 nuclear chromosome part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0000790 nuclear chromatin; GO:0005912 adherens junction; GO:0030014 CCR4-NOT complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005720 nuclear heterochromatin; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0000785 chromatin; GO:0000228 nuclear chromosome; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0050839 cell adhesion molecule binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0044877 macromolecular complex binding; GO:0005515 protein binding; GO:0019904 protein domain specific binding; GO:0071532 ankyrin repeat binding; GO:0019899 enzyme binding; ",{"$nulls":3},"IPR032764; ","\"Tankyrase 1-binding protein, C-terminal; \"\r"]
["Q9C0E8","Endoplasmic reticulum junction formation protein lunapark OS=Homo sapiens OX=9606 GN=LNPK","LNPK",47.739,17.905,16.8,7,9,7,1.125,1.14,1.094,0.86,0.949,0.914,0.811,0.0025,"plasma membrane\r","GO:0050794 regulation of cellular process; GO:0044085 cellular component biogenesis; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0043954 cellular component maintenance; GO:0010256 endomembrane system organization; GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0071787 endoplasmic reticulum tubular network formation; GO:0071786 endoplasmic reticulum tubular network organization; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:0007599 hemostasis; GO:0009611 response to wounding; GO:0009653 anatomical structure morphogenesis; GO:0035107 appendage morphogenesis; GO:0022607 cellular component assembly; GO:0060173 limb development; GO:0071788 endoplasmic reticulum tubular network maintenance; GO:0007275 multicellular organism development; GO:0032330 regulation of chondrocyte differentiation; GO:0009790 embryo development; GO:0009987 cellular process; GO:0061035 regulation of cartilage development; GO:0048598 embryonic morphogenesis; GO:0035113 embryonic appendage morphogenesis; GO:0045595 regulation of cell differentiation; GO:0032502 developmental process; GO:0050878 regulation of body fluid levels; GO:0006950 response to stress; GO:0042733 embryonic digit morphogenesis; GO:0044763 single-organism cellular process; GO:0032501 multicellular organismal process; GO:1902589 single-organism organelle organization; GO:0048736 appendage development; GO:0050789 regulation of biological process; GO:0042060 wound healing; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0035108 limb morphogenesis; GO:0030326 embryonic limb morphogenesis; GO:0035115 embryonic forelimb morphogenesis; GO:0035136 forelimb morphogenesis; GO:0050817 coagulation; GO:0050793 regulation of developmental process; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0065007 biological regulation; GO:0007029 endoplasmic reticulum organization; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044432 endoplasmic reticulum part; GO:0044425 membrane part; GO:0098826 endoplasmic reticulum tubular network membrane; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005488 binding; GO:0043167 ion binding; ",{"$nulls":3},"IPR019273; ","Lunapark domain; \r"]
["Q9GZM5","Protein YIPF3 OS=Homo sapiens OX=9606 GN=YIPF3","YIPF3",38.247,2.8541,2.6,1,2,1,1.009,0.9,0.955,1.017,1.081,1.04,1.096,0.07,"plasma membrane\r","GO:0032502 developmental process; GO:0030154 cell differentiation; GO:0044767 single-organism developmental process; GO:0048869 cellular developmental process; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0009987 cellular process; ","GO:0097708 intracellular vesicle; GO:0016020 membrane; GO:0043229 intracellular organelle; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0030133 transport vesicle; GO:0043227 membrane-bounded organelle; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; "]
["Q9GZP4","PITH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PITHD1","PITHD1",24.178,34.136,38.9,7,7,7,0.923,0.962,0.941,1.123,1.057,1.011,1.129,0.021,"cytoplasm\r","GO:0033554 cellular response to stress; GO:0051716 cellular response to stimulus; GO:0050896 response to stimulus; GO:0006950 response to stress; GO:0009987 cellular process; GO:0006974 cellular response to DNA damage stimulus; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; ",{"$nulls":4},"IPR008979; IPR010400; ","Galactose-binding domain-like; PITH domain; \r"]
["Q9GZS3","WD repeat-containing protein 61 OS=Homo sapiens OX=9606 GN=WDR61","WDR61",33.58,33.109,18.7,5,6,5,1.06,0.927,0.988,1.069,1.032,1.04,1.056,0.238,"cytoplasm\r","GO:0044700 single organism signaling; GO:0032270 positive regulation of cellular protein metabolic process; GO:0007166 cell surface receptor signaling pathway; GO:0097659 nucleic acid-templated transcription; GO:0009891 positive regulation of biosynthetic process; GO:0006354 DNA-templated transcription, elongation; GO:0044237 cellular metabolic process; GO:1905269 positive regulation of chromatin organization; GO:0008213 protein alkylation; GO:0008152 metabolic process; GO:0032784 regulation of DNA-templated transcription, elongation; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0016055 Wnt signaling pathway; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044763 single-organism cellular process; GO:0032786 positive regulation of DNA-templated transcription, elongation; GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0018022 peptidyl-lysine methylation; GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; GO:0051571 positive regulation of histone H3-K4 methylation; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0007267 cell-cell signaling; GO:0006402 mRNA catabolic process; GO:2001252 positive regulation of chromosome organization; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0031060 regulation of histone methylation; GO:0002682 regulation of immune system process; GO:0006464 cellular protein modification process; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0031062 positive regulation of histone methylation; GO:0016570 histone modification; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0051239 regulation of multicellular organismal process; GO:1903706 regulation of hemopoiesis; GO:0044270 cellular nitrogen compound catabolic process; GO:0006479 protein methylation; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0044248 cellular catabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0016569 covalent chromatin modification; GO:0034655 nucleobase-containing compound catabolic process; GO:0051254 positive regulation of RNA metabolic process; GO:0016567 protein ubiquitination; GO:1902275 regulation of chromatin organization; GO:0006368 transcription elongation from RNA polymerase II promoter; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0033044 regulation of chromosome organization; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0034243 regulation of transcription elongation from RNA polymerase II promoter; GO:0051569 regulation of histone H3-K4 methylation; GO:0051247 positive regulation of protein metabolic process; GO:0051276 chromosome organization; GO:0032446 protein modification by small protein conjugation; GO:0006996 organelle organization; GO:0043414 macromolecule methylation; GO:0031325 positive regulation of cellular metabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0043412 macromolecule modification; GO:0050793 regulation of developmental process; GO:0051093 negative regulation of developmental process; GO:0045637 regulation of myeloid cell differentiation; GO:0044699 single-organism process; GO:0051241 negative regulation of multicellular organismal process; GO:0009058 biosynthetic process; GO:0032259 methylation; GO:0051130 positive regulation of cellular component organization; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:1901361 organic cyclic compound catabolic process; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0045596 negative regulation of cell differentiation; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0051568 histone H3-K4 methylation; GO:0045638 negative regulation of myeloid cell differentiation; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0070647 protein modification by small protein conjugation or removal; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0198738 cell-cell signaling by wnt; GO:0002683 negative regulation of immune system process; GO:0016070 RNA metabolic process; GO:0006401 RNA catabolic process; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0010638 positive regulation of organelle organization; GO:0019222 regulation of metabolic process; GO:0006325 chromatin organization; GO:0080182 histone H3-K4 trimethylation; GO:0036211 protein modification process; GO:2000026 regulation of multicellular organismal development; GO:0016571 histone methylation; GO:0031056 regulation of histone modification; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0018205 peptidyl-lysine modification; GO:0031058 positive regulation of histone modification; GO:0034968 histone lysine methylation; GO:0018023 peptidyl-lysine trimethylation; GO:0034641 cellular nitrogen compound metabolic process; GO:1903707 negative regulation of hemopoiesis; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:2001160 regulation of histone H3-K79 methylation; GO:0006807 nitrogen compound metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0033043 regulation of organelle organization; GO:0031401 positive regulation of protein modification process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0018193 peptidyl-amino acid modification; GO:2001162 positive regulation of histone H3-K79 methylation; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0051246 regulation of protein metabolic process; GO:0009057 macromolecule catabolic process; GO:0006366 transcription from RNA polymerase II promoter; GO:0010467 gene expression; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0051128 regulation of cellular component organization; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; ","GO:0061695 transferase complex, transferring phosphorus-containing groups; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0016593 Cdc73/Paf1 complex; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0055029 nuclear DNA-directed RNA polymerase complex; GO:0000428 DNA-directed RNA polymerase complex; GO:0043232 intracellular non-membrane-bounded organelle; GO:0055087 Ski complex; GO:0044446 intracellular organelle part; GO:0030880 RNA polymerase complex; GO:0031981 nuclear lumen; GO:1990234 transferase complex; GO:0005829 cytosol; GO:0016591 DNA-directed RNA polymerase II, holoenzyme; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0000785 chromatin; GO:0035327 transcriptionally active chromatin; GO:0008023 transcription elongation factor complex; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0005488 binding; ","K12602","WDR61; WD repeat-containing protein 61","hsa03018 RNA degradation - Homo sapiens (human); ","IPR017986; IPR015943; ","WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain; \r"]
["Q9GZT8","NIF3-like protein 1 OS=Homo sapiens OX=9606 GN=NIF3L1","NIF3L1",41.968,7.1501,7.7,3,5,3,0.966,0.971,1.095,1.013,1.084,0.935,1,0.998,"mitochondria\r","GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0048869 cellular developmental process; GO:0009891 positive regulation of biosynthetic process; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0048523 negative regulation of cellular process; GO:0051253 negative regulation of RNA metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0030154 cell differentiation; GO:0009893 positive regulation of metabolic process; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0051254 positive regulation of RNA metabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0048731 system development; GO:0048699 generation of neurons; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0009892 negative regulation of metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0032501 multicellular organismal process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:1903506 regulation of nucleic acid-templated transcription; GO:0030182 neuron differentiation; GO:0009890 negative regulation of biosynthetic process; GO:0050789 regulation of biological process; GO:0044767 single-organism developmental process; GO:1902679 negative regulation of RNA biosynthetic process; GO:0031325 positive regulation of cellular metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0048856 anatomical structure development; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0065007 biological regulation; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0042802 identical protein binding; GO:0008134 transcription factor binding; GO:0005488 binding; "]
["Q9GZT9","Egl nine homolog 1 OS=Homo sapiens OX=9606 GN=EGLN1","EGLN1",46.02,10.427,10.1,4,5,4,0.96,1.009,0.892,1.063,1.069,1.009,1.098,0.0791,"cytoplasm\r","GO:0010941 regulation of cell death; GO:0060412 ventricular septum morphogenesis; GO:0065008 regulation of biological quality; GO:0030815 negative regulation of cAMP metabolic process; GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity; GO:0045980 negative regulation of nucleotide metabolic process; GO:0022414 reproductive process; GO:0043009 chordate embryonic development; GO:0060415 muscle tissue morphogenesis; GO:0009891 positive regulation of biosynthetic process; GO:0001892 embryonic placenta development; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0007507 heart development; GO:0060343 trabecula formation; GO:0044702 single organism reproductive process; GO:0055065 metal ion homeostasis; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009790 embryo development; GO:0051716 cellular response to stimulus; GO:0051174 regulation of phosphorus metabolic process; GO:0003006 developmental process involved in reproduction; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0060537 muscle tissue development; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044281 small molecule metabolic process; GO:0000302 response to reactive oxygen species; GO:0009894 regulation of catabolic process; GO:0055008 cardiac muscle tissue morphogenesis; GO:0044763 single-organism cellular process; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0061383 trabecula morphogenesis; GO:0032501 multicellular organismal process; GO:0046916 cellular transition metal ion homeostasis; GO:1903506 regulation of nucleic acid-templated transcription; GO:0071731 response to nitric oxide; GO:0048513 animal organ development; GO:0051336 regulation of hydrolase activity; GO:0001701 in utero embryonic development; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0051090 regulation of sequence-specific DNA binding transcription factor activity; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:1901698 response to nitrogen compound; GO:0048644 muscle organ morphogenesis; GO:0010604 positive regulation of macromolecule metabolic process; GO:0009887 animal organ morphogenesis; GO:0045765 regulation of angiogenesis; GO:0006464 cellular protein modification process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity; GO:0043436 oxoacid metabolic process; GO:0006140 regulation of nucleotide metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0000003 reproduction; GO:0072359 circulatory system development; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0044707 single-multicellular organism process; GO:0055076 transition metal ion homeostasis; GO:0001890 placenta development; GO:0009628 response to abiotic stimulus; GO:0044267 cellular protein metabolic process; GO:1901700 response to oxygen-containing compound; GO:0055072 iron ion homeostasis; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0051239 regulation of multicellular organismal process; GO:0003281 ventricular septum development; GO:0061384 heart trabecula morphogenesis; GO:0009653 anatomical structure morphogenesis; GO:0060411 cardiac septum morphogenesis; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0043620 regulation of DNA-templated transcription in response to stress; GO:0070482 response to oxygen levels; GO:0061061 muscle structure development; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0007275 multicellular organism development; GO:0061458 reproductive system development; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0003231 cardiac ventricle development; GO:0048878 chemical homeostasis; GO:0018126 protein hydroxylation; GO:0071456 cellular response to hypoxia; GO:0019511 peptidyl-proline hydroxylation; GO:0033121 regulation of purine nucleotide catabolic process; GO:0051254 positive regulation of RNA metabolic process; GO:0006950 response to stress; GO:0048731 system development; GO:0003279 cardiac septum development; GO:1901605 alpha-amino acid metabolic process; GO:0044238 primary metabolic process; GO:0003206 cardiac chamber morphogenesis; GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress; GO:0009892 negative regulation of metabolic process; GO:0030799 regulation of cyclic nucleotide metabolic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0031330 negative regulation of cellular catabolic process; GO:0030812 negative regulation of nucleotide catabolic process; GO:0006873 cellular ion homeostasis; GO:0031325 positive regulation of cellular metabolic process; GO:1900543 negative regulation of purine nucleotide metabolic process; GO:0036293 response to decreased oxygen levels; GO:0031328 positive regulation of cellular biosynthetic process; GO:0043412 macromolecule modification; GO:0050793 regulation of developmental process; GO:0045936 negative regulation of phosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity; GO:0030806 negative regulation of cyclic nucleotide catabolic process; GO:0044699 single-organism process; GO:0030811 regulation of nucleotide catabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0048729 tissue morphogenesis; GO:0006520 cellular amino acid metabolic process; GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0006979 response to oxidative stress; GO:0030814 regulation of cAMP metabolic process; GO:0019471 4-hydroxyproline metabolic process; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0010035 response to inorganic substance; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0009888 tissue development; GO:0050801 ion homeostasis; GO:0031326 regulation of cellular biosynthetic process; GO:0055114 oxidation-reduction process; GO:0003007 heart morphogenesis; GO:0098771 inorganic ion homeostasis; GO:0048608 reproductive structure development; GO:0032364 oxygen homeostasis; GO:0048522 positive regulation of cellular process; GO:0019725 cellular homeostasis; GO:0030820 regulation of cAMP catabolic process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0007517 muscle organ development; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0006082 organic acid metabolic process; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0006879 cellular iron ion homeostasis; GO:0014706 striated muscle tissue development; GO:0048738 cardiac muscle tissue development; GO:0060255 regulation of macromolecule metabolic process; GO:0048568 embryonic organ development; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0030003 cellular cation homeostasis; GO:0060711 labyrinthine layer development; GO:0030821 negative regulation of cAMP catabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0051346 negative regulation of hydrolase activity; GO:0055082 cellular chemical homeostasis; GO:0071704 organic substance metabolic process; GO:0030805 regulation of cyclic nucleotide catabolic process; GO:0042592 homeostatic process; GO:0006575 cellular modified amino acid metabolic process; GO:0055080 cation homeostasis; GO:0001666 response to hypoxia; GO:0009895 negative regulation of catabolic process; GO:0071453 cellular response to oxygen levels; GO:0009987 cellular process; GO:1901214 regulation of neuron death; GO:0006355 regulation of transcription, DNA-templated; GO:0009792 embryo development ending in birth or egg hatching; GO:1901342 regulation of vasculature development; GO:0006807 nitrogen compound metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0030800 negative regulation of cyclic nucleotide metabolic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0018208 peptidyl-proline modification; GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0033122 negative regulation of purine nucleotide catabolic process; GO:0003205 cardiac chamber development; GO:0018193 peptidyl-amino acid modification; GO:0033483 gas homeostasis; GO:1900542 regulation of purine nucleotide metabolic process; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0010563 negative regulation of phosphorus metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0006875 cellular metal ion homeostasis; GO:0060347 heart trabecula formation; GO:0036294 cellular response to decreased oxygen levels; GO:0065007 biological regulation; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0005829 cytosol; GO:0044444 cytoplasmic part; ","GO:0019842 vitamin binding; GO:0005506 iron ion binding; GO:0031418 L-ascorbic acid binding; GO:0031543 peptidyl-proline dioxygenase activity; GO:0043167 ion binding; GO:0043177 organic acid binding; GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; GO:0005515 protein binding; GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; GO:0048029 monosaccharide binding; GO:0016491 oxidoreductase activity; GO:0031406 carboxylic acid binding; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0051213 dioxygenase activity; GO:0005488 binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0030246 carbohydrate binding; GO:0043168 anion binding; GO:0031545 peptidyl-proline 4-dioxygenase activity; GO:0019899 enzyme binding; GO:0036094 small molecule binding; ","K09592","EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]","hsa05200 Pathways in cancer - Homo sapiens (human); hsa04066 HIF-1 signaling pathway - Homo sapiens (human); hsa05211 Renal cell carcinoma - Homo sapiens (human); ","IPR002893; IPR006620; IPR005123; ","\"Zinc finger, MYND-type; Prolyl 4-hydroxylase, alpha subunit; Oxoglutarate/iron-dependent dioxygenase; \"\r"]
["Q9GZZ9","Ubiquitin-like modifier-activating enzyme 5 OS=Homo sapiens OX=9606 GN=UBA5","UBA5",44.863,35.923,10.4,3,4,3,0.885,0.915,0.926,1.046,1.109,1.109,1.197,0.00162,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0051716 cellular response to stimulus; GO:0034976 response to endoplasmic reticulum stress; GO:0006950 response to stress; GO:0023051 regulation of signaling; GO:0044267 cellular protein metabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0050896 response to stimulus; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:1990592 protein K69-linked ufmylation; GO:0008152 metabolic process; GO:0050789 regulation of biological process; GO:0010646 regulation of cell communication; GO:0032446 protein modification by small protein conjugation; GO:0033146 regulation of intracellular estrogen receptor signaling pathway; GO:0071569 protein ufmylation; GO:1990564 protein polyufmylation; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0033143 regulation of intracellular steroid hormone receptor signaling pathway; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:0065007 biological regulation; ","GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:0008641 small protein activating enzyme activity; GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016874 ligase activity; GO:0005515 protein binding; GO:0016877 ligase activity, forming carbon-sulfur bonds; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0071566 UFM1 activating enzyme activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K12164",null,null,"IPR000594; IPR016040; ","THIF-type NAD/FAD binding fold; NAD(P)-binding domain; \r"]
["Q9H0A0","RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10","NAT10",115.73,10.956,3.7,3,3,3,0.818,0.897,0.9,1.004,1.203,1.163,1.289,0.0168,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0022613 ribonucleoprotein complex biogenesis; GO:0051391 tRNA acetylation; GO:0051129 negative regulation of cellular component organization; GO:0002101 tRNA wobble cytosine modification; GO:0032204 regulation of telomere maintenance; GO:0009451 RNA modification; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:1990882 rRNA acetylation; GO:0006364 rRNA processing; GO:2000279 negative regulation of DNA biosynthetic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0043170 macromolecule metabolic process; GO:1990884 RNA acetylation; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0016072 rRNA metabolic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0042254 ribosome biogenesis; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0016070 RNA metabolic process; GO:0010639 negative regulation of organelle organization; GO:0050789 regulation of biological process; GO:0051052 regulation of DNA metabolic process; GO:0090304 nucleic acid metabolic process; GO:0051053 negative regulation of DNA metabolic process; GO:0008033 tRNA processing; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0030490 maturation of SSU-rRNA; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0032210 regulation of telomere maintenance via telomerase; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0000154 rRNA modification; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0032844 regulation of homeostatic process; GO:0032211 negative regulation of telomere maintenance via telomerase; GO:0071704 organic substance metabolic process; GO:1904356 regulation of telomere maintenance via telomere lengthening; GO:1904357 negative regulation of telomere maintenance via telomere lengthening; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:1904812 rRNA acetylation involved in maturation of SSU-rRNA; GO:0034641 cellular nitrogen compound metabolic process; GO:0006400 tRNA modification; GO:0009987 cellular process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0042274 ribosomal small subunit biogenesis; GO:0006807 nitrogen compound metabolic process; GO:0033043 regulation of organelle organization; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0032845 negative regulation of homeostatic process; GO:0044238 primary metabolic process; GO:2000278 regulation of DNA biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0033044 regulation of chromosome organization; GO:0032205 negative regulation of telomere maintenance; GO:0009890 negative regulation of biosynthetic process; GO:2001251 negative regulation of chromosome organization; GO:0006399 tRNA metabolic process; GO:0002097 tRNA wobble base modification; GO:0010467 gene expression; GO:0051128 regulation of cellular component organization; GO:0031327 negative regulation of cellular biosynthetic process; GO:0043412 macromolecule modification; GO:0034660 ncRNA metabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0000784 nuclear chromosome, telomeric region; GO:0000781 chromosome, telomeric region; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0030684 preribosome; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044454 nuclear chromosome part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0030496 midbody; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0098687 chromosomal region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0030686 90S preribosome; GO:0000228 nuclear chromosome; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0005515 protein binding; GO:0008080 N-acetyltransferase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016746 transferase activity, transferring acyl groups; GO:0000049 tRNA binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0051392 tRNA N-acetyltransferase activity; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003723 RNA binding; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups; GO:0016407 acetyltransferase activity; GO:0016410 N-acyltransferase activity; GO:0032549 ribonucleoside binding; GO:1990883 rRNA cytidine N-acetyltransferase activity; GO:0097367 carbohydrate derivative binding; GO:0003676 nucleic acid binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; ","K14521","NAT10; N-acetyltransferase 10 [EC:2.3.1.-]","hsa03008 Ribosome biogenesis in eukaryotes - Homo sapiens (human); ","IPR013562; IPR000182; IPR007807; IPR027992; IPR016181; ","\"tRNA(Met) cytidine acetyltransferase TmcA, N-terminal; GNAT domain; Helicase domain; Possible tRNA binding domain; Acyl-CoA N-acyltransferase; \"\r"]
["Q9H0D6","5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2","XRN2",108.58,30.927,8,6,8,6,0.938,0.974,0.913,1.077,1.081,1.088,1.149,0.0181,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0006308 DNA catabolic process; GO:0021766 hippocampus development; GO:0022414 reproductive process; GO:0097659 nucleic acid-templated transcription; GO:0007420 brain development; GO:0048869 cellular developmental process; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0021761 limbic system development; GO:0044237 cellular metabolic process; GO:0006353 DNA-templated transcription, termination; GO:0021537 telencephalon development; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0006364 rRNA processing; GO:0044702 single organism reproductive process; GO:1901361 organic cyclic compound catabolic process; GO:0060322 head development; GO:0043170 macromolecule metabolic process; GO:0016072 rRNA metabolic process; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0016049 cell growth; GO:0044763 single-organism cellular process; GO:0019953 sexual reproduction; GO:0042254 ribosome biogenesis; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0006401 RNA catabolic process; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0019439 aromatic compound catabolic process; GO:1901575 organic substance catabolic process; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0007417 central nervous system development; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0090305 nucleic acid phosphodiester bond hydrolysis; GO:0016071 mRNA metabolic process; GO:0048609 multicellular organismal reproductive process; GO:0048856 anatomical structure development; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0000003 reproduction; GO:0050794 regulation of cellular process; GO:0021543 pallium development; GO:0044707 single-multicellular organism process; GO:0043010 camera-type eye development; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0006259 DNA metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic; GO:0000738 DNA catabolic process, exonucleolytic; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0030154 cell differentiation; GO:0001654 eye development; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0044248 cellular catabolic process; GO:0030900 forebrain development; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0034655 nucleobase-containing compound catabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0060041 retina development in camera-type eye; GO:0044265 cellular macromolecule catabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0048232 male gamete generation; GO:0007283 spermatogenesis; GO:0048731 system development; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:0051252 regulation of RNA metabolic process; GO:1901576 organic substance biosynthetic process; GO:0007276 gamete generation; GO:0044249 cellular biosynthetic process; GO:0032504 multicellular organism reproduction; GO:0030182 neuron differentiation; GO:0090501 RNA phosphodiester bond hydrolysis; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0044767 single-organism developmental process; GO:0044703 multi-organism reproductive process; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0007423 sensory organ development; GO:0040007 growth; GO:0034660 ncRNA metabolic process; GO:0009056 catabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; GO:0046700 heterocycle catabolic process; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0043232 intracellular non-membrane-bounded organelle; GO:0016234 inclusion body; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005730 nucleolus; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0016235 aggresome; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0003690 double-stranded DNA binding; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0001147 transcription termination site sequence-specific DNA binding; GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters; GO:1901363 heterocyclic compound binding; GO:0000975 regulatory region DNA binding; GO:0097159 organic cyclic compound binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043169 cation binding; GO:0008409 5'-3' exonuclease activity; GO:0004540 ribonuclease activity; GO:0003677 DNA binding; GO:0003723 RNA binding; GO:0000976 transcription regulatory region sequence-specific DNA binding; GO:0000175 3'-5'-exoribonuclease activity; GO:0043167 ion binding; GO:1990837 sequence-specific double-stranded DNA binding; GO:0016896 exoribonuclease activity, producing 5'-phosphomonoesters; GO:0008408 3'-5' exonuclease activity; GO:0043565 sequence-specific DNA binding; GO:0001067 regulatory region nucleic acid binding; GO:0004534 5'-3' exoribonuclease activity; GO:0044212 transcription regulatory region DNA binding; GO:0004532 exoribonuclease activity; GO:0003676 nucleic acid binding; GO:0004518 nuclease activity; GO:0016788 hydrolase activity, acting on ester bonds; GO:0004527 exonuclease activity; GO:0046872 metal ion binding; GO:0001160 transcription termination site DNA binding; ","K12619","XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]","hsa03018 RNA degradation - Homo sapiens (human); hsa03008 Ribosome biogenesis in eukaryotes - Homo sapiens (human); ","IPR004859; ","Putative 5-3 exonuclease; \r"]
["Q9H0N0","Ras-related protein Rab-6C OS=Homo sapiens OX=9606 GN=RAB6C","RAB6C",28.355,27.236,11.4,2,3,1,1.016,1.046,0.968,0.98,1.071,0.929,0.983,0.725,"nucleus\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0046907 intracellular transport; GO:0044699 single-organism process; GO:0048193 Golgi vesicle transport; GO:0050896 response to stimulus; GO:0010564 regulation of cell cycle process; GO:0051234 establishment of localization; GO:0042493 response to drug; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0010824 regulation of centrosome duplication; GO:0051493 regulation of cytoskeleton organization; GO:0016482 cytosolic transport; GO:0051726 regulation of cell cycle; GO:0009987 cellular process; GO:0051716 cellular response to stimulus; GO:0070507 regulation of microtubule cytoskeleton organization; GO:0035556 intracellular signal transduction; GO:0006891 intra-Golgi vesicle-mediated transport; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0033043 regulation of organelle organization; GO:0007264 small GTPase mediated signal transduction; GO:0023052 signaling; GO:0051641 cellular localization; GO:0006810 transport; GO:0016197 endosomal transport; GO:0032886 regulation of microtubule-based process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0042147 retrograde transport, endosome to Golgi; GO:0006890 retrograde vesicle-mediated transport, Golgi to ER; GO:0022402 cell cycle process; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0007049 cell cycle; GO:0046605 regulation of centrosome cycle; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0005856 cytoskeleton; GO:0043231 intracellular membrane-bounded organelle; GO:0005815 microtubule organizing center; GO:0005634 nucleus; GO:0015630 microtubule cytoskeleton; GO:0005813 centrosome; GO:0005622 intracellular; GO:0044464 cell part; GO:0005794 Golgi apparatus; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0003924 GTPase activity; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019001 guanyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0036094 small molecule binding; ","K07895",null,null,"IPR005225; IPR027417; ","Small GTP-binding protein domain; P-loop containing nucleoside triphosphate hydrolase; \r"]
["Q9H0U4","Ras-related protein Rab-1B OS=Homo sapiens OX=9606 GN=RAB1B","RAB1B",22.171,33.376,41.3,8,28,2,0.969,0.842,1.005,1.133,1.015,0.977,1.11,0.207,"cytoplasm\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0006901 vesicle coating; GO:0048207 vesicle targeting, rough ER to cis-Golgi; GO:0048208 COPII vesicle coating; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0006914 autophagy; GO:1902115 regulation of organelle assembly; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:1903020 positive regulation of glycoprotein metabolic process; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0048199 vesicle targeting, to, from or within Golgi; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0044419 interspecies interaction between organisms; GO:0051716 cellular response to stimulus; GO:0051650 establishment of vesicle localization; GO:0044088 regulation of vacuole organization; GO:0071822 protein complex subunit organization; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0007264 small GTPase mediated signal transduction; GO:0031323 regulation of cellular metabolic process; GO:0023052 signaling; GO:0010506 regulation of autophagy; GO:0051704 multi-organism process; GO:0016241 regulation of macroautophagy; GO:0006810 transport; GO:2000785 regulation of autophagosome assembly; GO:0050789 regulation of biological process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0070271 protein complex biogenesis; GO:0051640 organelle localization; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0019068 virion assembly; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0048193 Golgi vesicle transport; GO:0044087 regulation of cellular component biogenesis; GO:0006903 vesicle targeting; GO:0050896 response to stimulus; GO:0016032 viral process; GO:0051648 vesicle localization; GO:0044248 cellular catabolic process; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0090114 COPII-coated vesicle budding; GO:0035556 intracellular signal transduction; GO:0016192 vesicle-mediated transport; GO:1903018 regulation of glycoprotein metabolic process; GO:0033043 regulation of organelle organization; GO:0016050 vesicle organization; GO:0071702 organic substance transport; GO:0051656 establishment of organelle localization; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0043933 macromolecular complex subunit organization; GO:0045184 establishment of protein localization; GO:0051247 positive regulation of protein metabolic process; GO:0006890 retrograde vesicle-mediated transport, Golgi to ER; GO:0051246 regulation of protein metabolic process; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0006900 membrane budding; GO:0061024 membrane organization; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0034045 pre-autophagosomal structure membrane; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0043227 membrane-bounded organelle; GO:0000407 pre-autophagosomal structure; GO:0005789 endoplasmic reticulum membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044432 endoplasmic reticulum part; GO:0005793 endoplasmic reticulum-Golgi intermediate compartment; GO:0030133 transport vesicle; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0036094 small molecule binding; ","K07875","RAB1B; Ras-related protein Rab-1B","hsa05134 Legionellosis - Homo sapiens (human); ","IPR005225; IPR027417; ","Small GTP-binding protein domain; P-loop containing nucleoside triphosphate hydrolase; \r"]
["Q9H1E1","Ribonuclease 7 OS=Homo sapiens OX=9606 GN=RNASE7","RNASE7",17.419,28.044,30.8,3,4,3,0.806,0.929,0.887,1.173,1.12,1.143,1.31,3.46E-3,"extracellular\r","GO:0065008 regulation of biological quality; GO:0006725 cellular aromatic compound metabolic process; GO:0098542 defense response to other organism; GO:0006959 humoral immune response; GO:0043207 response to external biotic stimulus; GO:0035821 modification of morphology or physiology of other organism; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0051707 response to other organism; GO:0045087 innate immune response; GO:0071704 organic substance metabolic process; GO:0009607 response to biotic stimulus; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0009987 cellular process; GO:0019731 antibacterial humoral response; GO:0009617 response to bacterium; GO:0050829 defense response to Gram-negative bacterium; GO:0006950 response to stress; GO:0042742 defense response to bacterium; GO:0019730 antimicrobial humoral response; GO:0051673 membrane disruption in other organism; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:0050830 defense response to Gram-positive bacterium; GO:0051704 multi-organism process; GO:0016070 RNA metabolic process; GO:0090501 RNA phosphodiester bond hydrolysis; GO:0090304 nucleic acid metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006952 defense response; GO:0090305 nucleic acid phosphodiester bond hydrolysis; GO:0006955 immune response; GO:0065007 biological regulation; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:0042834 peptidoglycan binding; GO:0016787 hydrolase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0097367 carbohydrate derivative binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0004518 nuclease activity; GO:0008289 lipid binding; GO:0001530 lipopolysaccharide binding; GO:0005539 glycosaminoglycan binding; GO:0004540 ribonuclease activity; GO:0004519 endonuclease activity; ","K01172",null,null,"IPR023412; ","Ribonuclease A-domain; \r"]
["Q9H1E5","Thioredoxin-related transmembrane protein 4 OS=Homo sapiens OX=9606 GN=TMX4","TMX4",38.952,32.537,10.6,4,7,4,1.084,1.043,1.098,0.924,0.919,0.928,0.859,0.000642,"extracellular\r","GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0051716 cellular response to stimulus; GO:0065008 regulation of biological quality; GO:0034976 response to endoplasmic reticulum stress; GO:0006950 response to stress; GO:0055114 oxidation-reduction process; GO:0045454 cell redox homeostasis; GO:0044763 single-organism cellular process; GO:0019725 cellular homeostasis; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0006457 protein folding; GO:0042592 homeostatic process; GO:0008152 metabolic process; GO:0050789 regulation of biological process; GO:0044710 single-organism metabolic process; GO:0009987 cellular process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds; GO:0016853 isomerase activity; GO:0016860 intramolecular oxidoreductase activity; GO:0003756 protein disulfide isomerase activity; GO:0003824 catalytic activity; ",{"$nulls":3},"IPR013766; IPR012336; ","Thioredoxin domain; Thioredoxin-like fold; \r"]
["Q9H1H9","Kinesin-like protein KIF13A OS=Homo sapiens OX=9606 GN=KIF13A","KIF13A",202.31,3.4191,2.7,4,6,1,0.877,0.85,1.116,1.072,1.044,1.037,1.109,0.329,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0010256 endomembrane system organization; GO:0035459 cargo loading into vesicle; GO:0090002 establishment of protein localization to plasma membrane; GO:0044699 single-organism process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0010970 transport along microtubule; GO:0051649 establishment of localization in cell; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0006893 Golgi to plasma membrane transport; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0032438 melanosome organization; GO:0044765 single-organism transport; GO:0051650 establishment of vesicle localization; GO:0072657 protein localization to membrane; GO:0044763 single-organism cellular process; GO:0007009 plasma membrane organization; GO:0008333 endosome to lysosome transport; GO:1902582 single-organism intracellular transport; GO:0016197 endosomal transport; GO:0006810 transport; GO:0099518 vesicle cytoskeletal trafficking; GO:0051301 cell division; GO:0051640 organelle localization; GO:0072384 organelle transport along microtubule; GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0048193 Golgi vesicle transport; GO:0099111 microtubule-based transport; GO:0030705 cytoskeleton-dependent intracellular transport; GO:1990778 protein localization to cell periphery; GO:1902578 single-organism localization; GO:0000910 cytokinesis; GO:0051648 vesicle localization; GO:0006886 intracellular protein transport; GO:1902580 single-organism cellular localization; GO:0043001 Golgi to plasma membrane protein transport; GO:0072386 plus-end-directed organelle transport along microtubule; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0090150 establishment of protein localization to membrane; GO:0007041 lysosomal transport; GO:0034622 cellular macromolecular complex assembly; GO:0048753 pigment granule organization; GO:0098876 vesicle-mediated transport to the plasma membrane; GO:0016192 vesicle-mediated transport; GO:0044802 single-organism membrane organization; GO:0016050 vesicle organization; GO:0071702 organic substance transport; GO:0051656 establishment of organelle localization; GO:0007017 microtubule-based process; GO:0047496 vesicle transport along microtubule; GO:0051641 cellular localization; GO:0043933 macromolecular complex subunit organization; GO:0045184 establishment of protein localization; GO:0007018 microtubule-based movement; GO:0070727 cellular macromolecule localization; GO:0072659 protein localization to plasma membrane; GO:0072383 plus-end-directed vesicle transport along microtubule; GO:0006996 organelle organization; GO:0007034 vacuolar transport; GO:0061024 membrane organization; GO:0043473 pigmentation; GO:0006928 movement of cell or subcellular component; GO:0022402 cell cycle process; GO:0051179 localization; GO:0006892 post-Golgi vesicle-mediated transport; GO:0033059 cellular pigmentation; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0005874 microtubule; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0032588 trans-Golgi network membrane; GO:0044424 intracellular part; GO:0099512 supramolecular fiber; GO:0005623 cell; GO:0099080 supramolecular complex; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0005815 microtubule organizing center; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0098791 Golgi subcompartment; GO:0044431 Golgi apparatus part; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0010008 endosome membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0030496 midbody; GO:0000139 Golgi membrane; GO:0044440 endosomal part; GO:0012505 endomembrane system; GO:0005875 microtubule associated complex; GO:0099081 supramolecular polymer; GO:0005871 kinesin complex; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005813 centrosome; GO:0005802 trans-Golgi network; GO:0043234 protein complex; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; GO:0031984 organelle subcompartment; ","GO:1901265 nucleoside phosphate binding; GO:0003774 motor activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0016887 ATPase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0008092 cytoskeletal protein binding; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0008017 microtubule binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0003777 microtubule motor activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0015631 tubulin binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; ","K17914",null,null,"IPR008984; IPR022140; IPR027417; IPR022164; IPR032405; IPR001752; IPR000253; ","SMAD/FHA domain; Kinesin-like KIF1-type; P-loop containing nucleoside triphosphate hydrolase; Kinesin-like; Kinesin-associated; Kinesin motor domain; Forkhead-associated (FHA) domain; \r"]
["Q9H269","Vacuolar protein sorting-associated protein 16 homolog OS=Homo sapiens OX=9606 GN=VPS16","VPS16",94.693,52.766,11.6,6,6,6,0.803,1.033,0.845,1.123,1.135,1.06,1.238,0.0518,"nucleus\r","GO:0050794 regulation of cellular process; GO:0060627 regulation of vesicle-mediated transport; GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0044699 single-organism process; GO:0097352 autophagosome maturation; GO:0044087 regulation of cellular component biogenesis; GO:0031338 regulation of vesicle fusion; GO:0006914 autophagy; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0032889 regulation of vacuole fusion, non-autophagic; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0032879 regulation of localization; GO:0006886 intracellular protein transport; GO:0044248 cellular catabolic process; GO:0007033 vacuole organization; GO:0034613 cellular protein localization; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0009987 cellular process; GO:0016236 macroautophagy; GO:0007041 lysosomal transport; GO:0044088 regulation of vacuole organization; GO:0051049 regulation of transport; GO:0044763 single-organism cellular process; GO:0033043 regulation of organelle organization; GO:0071702 organic substance transport; GO:0048284 organelle fusion; GO:0008333 endosome to lysosome transport; GO:0035542 regulation of SNARE complex assembly; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0016197 endosomal transport; GO:0006810 transport; GO:1902589 single-organism organelle organization; GO:0070727 cellular macromolecule localization; GO:0043254 regulation of protein complex assembly; GO:0050789 regulation of biological process; GO:0097576 vacuole fusion; GO:0006996 organelle organization; GO:0007034 vacuolar transport; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0009056 catabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0043025 neuronal cell body; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0005776 autophagosome; GO:0055037 recycling endosome; GO:0005765 lysosomal membrane; GO:0030136 clathrin-coated vesicle; GO:0044425 membrane part; GO:0031902 late endosome membrane; GO:0044464 cell part; GO:0005622 intracellular; GO:0098805 whole membrane; GO:0005764 lysosome; GO:0043005 neuron projection; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0099023 tethering complex; GO:0000323 lytic vacuole; GO:0010008 endosome membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0042995 cell projection; GO:0005770 late endosome; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0044440 endosomal part; GO:0012505 endomembrane system; GO:0030135 coated vesicle; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0030424 axon; GO:0036477 somatodendritic compartment; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0044297 cell body; GO:0030897 HOPS complex; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0051015 actin filament binding; GO:0008092 cytoskeletal protein binding; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0003779 actin binding; GO:0005515 protein binding; GO:0032403 protein complex binding; ","K20180",null,null,"IPR006926; IPR006925; ","\"Vps16, N-terminal; Vps16, C-terminal; \"\r"]
["Q9H270","Vacuolar protein sorting-associated protein 11 homolog OS=Homo sapiens OX=9606 GN=VPS11","VPS11",107.84,26.367,8.4,7,8,7,1.156,1.08,1.007,0.879,0.947,0.95,0.856,0.0307,"cytoplasm\r","GO:0060627 regulation of vesicle-mediated transport; GO:0010256 endomembrane system organization; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:1903955 positive regulation of protein targeting to mitochondrion; GO:1903533 regulation of protein targeting; GO:0031331 positive regulation of cellular catabolic process; GO:0044699 single-organism process; GO:0031338 regulation of vesicle fusion; GO:0006914 autophagy; GO:1902115 regulation of organelle assembly; GO:0044237 cellular metabolic process; GO:0010821 regulation of mitochondrion organization; GO:0015031 protein transport; GO:1903749 positive regulation of establishment of protein localization to mitochondrion; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:1903364 positive regulation of cellular protein catabolic process; GO:0008152 metabolic process; GO:1903651 positive regulation of cytoplasmic transport; GO:0051649 establishment of localization in cell; GO:0009893 positive regulation of metabolic process; GO:1903747 regulation of establishment of protein localization to mitochondrion; GO:0032879 regulation of localization; GO:0007033 vacuole organization; GO:0044801 single-organism membrane fusion; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:1903362 regulation of cellular protein catabolic process; GO:0046903 secretion; GO:0044765 single-organism transport; GO:2000643 positive regulation of early endosome to late endosome transport; GO:0006904 vesicle docking involved in exocytosis; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:1903649 regulation of cytoplasmic transport; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0061025 membrane fusion; GO:0048522 positive regulation of cellular process; GO:0032386 regulation of intracellular transport; GO:0008333 endosome to lysosome transport; GO:0031323 regulation of cellular metabolic process; GO:0007040 lysosome organization; GO:0051050 positive regulation of transport; GO:0016197 endosomal transport; GO:0006810 transport; GO:1902589 single-organism organelle organization; GO:0043254 regulation of protein complex assembly; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0010638 positive regulation of organelle organization; GO:0032940 secretion by cell; GO:0006906 vesicle fusion; GO:0019222 regulation of metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051223 regulation of protein transport; GO:0051222 positive regulation of protein transport; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0090174 organelle membrane fusion; GO:0046907 intracellular transport; GO:0090316 positive regulation of intracellular protein transport; GO:1903829 positive regulation of cellular protein localization; GO:0060255 regulation of macromolecule metabolic process; GO:0044087 regulation of cellular component biogenesis; GO:0022406 membrane docking; GO:0070201 regulation of establishment of protein localization; GO:0060341 regulation of cellular localization; GO:1902578 single-organism localization; GO:0009896 positive regulation of catabolic process; GO:2000641 regulation of early endosome to late endosome transport; GO:0006886 intracellular protein transport; GO:0044248 cellular catabolic process; GO:0042176 regulation of protein catabolic process; GO:0032880 regulation of protein localization; GO:0034613 cellular protein localization; GO:0034058 endosomal vesicle fusion; GO:0033157 regulation of intracellular protein transport; GO:0009987 cellular process; GO:0007041 lysosomal transport; GO:0032388 positive regulation of intracellular transport; GO:0051049 regulation of transport; GO:0016192 vesicle-mediated transport; GO:0044802 single-organism membrane organization; GO:0016050 vesicle organization; GO:0033043 regulation of organelle organization; GO:0048284 organelle fusion; GO:1903214 regulation of protein targeting to mitochondrion; GO:0071702 organic substance transport; GO:0048278 vesicle docking; GO:0035542 regulation of SNARE complex assembly; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0010822 positive regulation of mitochondrion organization; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0051247 positive regulation of protein metabolic process; GO:1904951 positive regulation of establishment of protein localization; GO:0007034 vacuolar transport; GO:0006996 organelle organization; GO:0051246 regulation of protein metabolic process; GO:0061024 membrane organization; GO:0031325 positive regulation of cellular metabolic process; GO:0080171 lytic vacuole organization; GO:0031647 regulation of protein stability; GO:0045732 positive regulation of protein catabolic process; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0007032 endosome organization; GO:0009056 catabolic process; GO:1903827 regulation of cellular protein localization; GO:0006887 exocytosis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005776 autophagosome; GO:0005769 early endosome; GO:0005765 lysosomal membrane; GO:0030136 clathrin-coated vesicle; GO:0044425 membrane part; GO:0031902 late endosome membrane; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005764 lysosome; GO:0005768 endosome; GO:0030139 endocytic vesicle; GO:0043227 membrane-bounded organelle; GO:0099023 tethering complex; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0010008 endosome membrane; GO:0005770 late endosome; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0044440 endosomal part; GO:0012505 endomembrane system; GO:0030135 coated vesicle; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0030897 HOPS complex; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0000149 SNARE binding; GO:1901265 nucleoside phosphate binding; GO:0030674 protein binding, bridging; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0008270 zinc ion binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0046914 transition metal ion binding; GO:0005488 binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0060090 binding, bridging; GO:0019904 protein domain specific binding; GO:0019905 syntaxin binding; GO:0036094 small molecule binding; ","K20179",null,null,"IPR001841; IPR011990; IPR017986; IPR013083; IPR024763; IPR015943; IPR016024; ","\"Zinc finger, RING-type; Tetratricopeptide-like helical domain; WD40-repeat-containing domain; Zinc finger, RING/FYVE/PHD-type; Vacuolar protein sorting protein 11, C-terminal; WD40/YVTN repeat-like-containing domain; Armadillo-type fold; \"\r"]
["Q9H2D6","TRIO and F-actin-binding protein OS=Homo sapiens OX=9606 GN=TRIOBP","TRIOBP",261.37,18.547,3.3,7,7,7,1.033,1.069,1.102,0.911,0.957,0.943,0.877,5.28E-3,"nucleus\r","GO:0030833 regulation of actin filament polymerization; GO:0065008 regulation of biological quality; GO:0030835 negative regulation of actin filament depolymerization; GO:0051129 negative regulation of cellular component organization; GO:0007067 mitotic nuclear division; GO:0044699 single-organism process; GO:0030832 regulation of actin filament length; GO:0044237 cellular metabolic process; GO:0051130 positive regulation of cellular component organization; GO:0051693 actin filament capping; GO:0008152 metabolic process; GO:0030036 actin cytoskeleton organization; GO:0032535 regulation of cellular component size; GO:0032271 regulation of protein polymerization; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0051493 regulation of cytoskeleton organization; GO:0010720 positive regulation of cell development; GO:0031333 negative regulation of protein complex assembly; GO:0000278 mitotic cell cycle; GO:0051494 negative regulation of cytoskeleton organization; GO:1900026 positive regulation of substrate adhesion-dependent cell spreading; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0010811 positive regulation of cell-substrate adhesion; GO:1902589 single-organism organelle organization; GO:0010639 negative regulation of organelle organization; GO:0043254 regulation of protein complex assembly; GO:0050789 regulation of biological process; GO:0051016 barbed-end actin filament capping; GO:0044710 single-organism metabolic process; GO:0043242 negative regulation of protein complex disassembly; GO:0044260 cellular macromolecule metabolic process; GO:1902904 negative regulation of supramolecular fiber organization; GO:0006464 cellular protein modification process; GO:0030837 negative regulation of actin filament polymerization; GO:0051301 cell division; GO:0043244 regulation of protein complex disassembly; GO:0030834 regulation of actin filament depolymerization; GO:0036211 protein modification process; GO:0051094 positive regulation of developmental process; GO:1902903 regulation of supramolecular fiber organization; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0032956 regulation of actin cytoskeleton organization; GO:0048285 organelle fission; GO:0044267 cellular protein metabolic process; GO:0010770 positive regulation of cell morphogenesis involved in differentiation; GO:0044087 regulation of cellular component biogenesis; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0045597 positive regulation of cell differentiation; GO:0071704 organic substance metabolic process; GO:1901880 negative regulation of protein depolymerization; GO:1900024 regulation of substrate adhesion-dependent cell spreading; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0045785 positive regulation of cell adhesion; GO:0060284 regulation of cell development; GO:1901879 regulation of protein depolymerization; GO:0033043 regulation of organelle organization; GO:0032970 regulation of actin filament-based process; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0030155 regulation of cell adhesion; GO:0008064 regulation of actin polymerization or depolymerization; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0000280 nuclear division; GO:0090066 regulation of anatomical structure size; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:0051128 regulation of cellular component organization; GO:0022402 cell cycle process; GO:0043412 macromolecule modification; GO:0032272 negative regulation of protein polymerization; GO:0010810 regulation of cell-substrate adhesion; GO:0022604 regulation of cell morphogenesis; GO:0050793 regulation of developmental process; GO:0007049 cell cycle; GO:0030047 actin modification; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0030054 cell junction; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0070161 anchoring junction; GO:0030496 midbody; GO:0044424 intracellular part; GO:0005623 cell; GO:0015629 actin cytoskeleton; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005815 microtubule organizing center; GO:0005634 nucleus; GO:0005925 focal adhesion; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; ","GO:0031267 small GTPase binding; GO:0051015 actin filament binding; GO:0017048 Rho GTPase binding; GO:0045159 myosin II binding; GO:0031625 ubiquitin protein ligase binding; GO:0044877 macromolecular complex binding; GO:0005515 protein binding; GO:0017049 GTP-Rho binding; GO:0008092 cytoskeletal protein binding; GO:0017016 Ras GTPase binding; GO:0005488 binding; GO:0003779 actin binding; GO:0017022 myosin binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0051020 GTPase binding; GO:0019899 enzyme binding; GO:0032403 protein complex binding; ",{"$nulls":3},"IPR011993; IPR001849; ","PH domain-like; Pleckstrin homology domain; \r"]
["Q9H2H8","Peptidyl-prolyl cis-trans isomerase-like 3 OS=Homo sapiens OX=9606 GN=PPIL3","PPIL3",18.154,23.24,30.4,4,5,4,1.022,1.011,0.993,1.04,0.987,0.986,0.996,0.827,"cytoplasm\r","GO:0006725 cellular aromatic compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0006457 protein folding; GO:0000398 mRNA splicing, via spliceosome; GO:0008152 metabolic process; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0034641 cellular nitrogen compound metabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0006396 RNA processing; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0044238 primary metabolic process; GO:0018208 peptidyl-proline modification; GO:0000413 protein peptidyl-prolyl isomerization; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:0018193 peptidyl-amino acid modification; GO:0090304 nucleic acid metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0006464 cellular protein modification process; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:0016071 mRNA metabolic process; ","GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005681 spliceosomal complex; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:1902494 catalytic complex; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0071013 catalytic step 2 spliceosome; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0044428 nuclear part; ","GO:0003755 peptidyl-prolyl cis-trans isomerase activity; GO:0005515 protein binding; GO:0016853 isomerase activity; GO:0003824 catalytic activity; GO:0016859 cis-trans isomerase activity; GO:0005488 binding; ","K12734",null,null,"IPR002130; IPR029000; ","Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain; Cyclophilin-like domain; \r"]
["Q9H2V7","Protein spinster homolog 1 OS=Homo sapiens OX=9606 GN=SPNS1","SPNS1",56.629,5.01,3.6,2,2,2,1.007,1.205,0.759,1.153,0.968,0.932,1.028,0.8,"plasma membrane\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0090520 sphingolipid mediated signaling pathway; GO:0051716 cellular response to stimulus; GO:0006869 lipid transport; GO:0044699 single-organism process; GO:0071702 organic substance transport; GO:0010876 lipid localization; GO:0023052 signaling; GO:0050896 response to stimulus; GO:0051234 establishment of localization; GO:0006810 transport; GO:0007186 G-protein coupled receptor signaling pathway; GO:0003376 sphingosine-1-phosphate signaling pathway; GO:0055085 transmembrane transport; GO:0007165 signal transduction; GO:0050789 regulation of biological process; GO:1902578 single-organism localization; GO:0007154 cell communication; GO:0040011 locomotion; GO:0033036 macromolecule localization; GO:0051179 localization; GO:0009987 cellular process; GO:0044765 single-organism transport; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0005765 lysosomal membrane; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0098805 whole membrane; GO:0005764 lysosome; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0044429 mitochondrial part; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0016021 integral component of membrane; GO:0005739 mitochondrion; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031975 envelope; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0005319 lipid transporter activity; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0005488 binding; GO:0046624 sphingolipid transporter activity; GO:0005215 transporter activity; ",{"$nulls":3},"IPR020846; ","Major facilitator superfamily domain; \r"]
["Q9H2X3","C-type lectin domain family 4 member M OS=Homo sapiens OX=9606 GN=CLEC4M","CLEC4M",45.35,2.7858,6,1,1,1,0.979,0.888,1.021,0.966,1.147,0.997,1.077,0.338,"cytoplasm\r","GO:0044409 entry into host; GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0019079 viral genome replication; GO:0046968 peptide antigen transport; GO:0044699 single-organism process; GO:1902581 multi-organism cellular localization; GO:0044764 multi-organism cellular process; GO:0035821 modification of morphology or physiology of other organism; GO:0051234 establishment of localization; GO:1902583 multi-organism intracellular transport; GO:0022610 biological adhesion; GO:0007165 signal transduction; GO:0016337 single organismal cell-cell adhesion; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0002250 adaptive immune response; GO:0044003 modification by symbiont of host morphology or physiology; GO:1900046 regulation of hemostasis; GO:0007155 cell adhesion; GO:0075733 intracellular transport of virus; GO:0042886 amide transport; GO:0044419 interspecies interaction between organisms; GO:0046718 viral entry into host cell; GO:0010468 regulation of gene expression; GO:0051716 cellular response to stimulus; GO:0048002 antigen processing and presentation of peptide antigen; GO:0044763 single-organism cellular process; GO:0098609 cell-cell adhesion; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0023052 signaling; GO:0051704 multi-organism process; GO:0006810 transport; GO:0030260 entry into host cell; GO:0050789 regulation of biological process; GO:0051828 entry into other organism involved in symbiotic interaction; GO:0048583 regulation of response to stimulus; GO:0098602 single organism cell adhesion; GO:0019222 regulation of metabolic process; GO:0006952 defense response; GO:0015833 peptide transport; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:1902579 multi-organism localization; GO:0007159 leukocyte cell-cell adhesion; GO:0060255 regulation of macromolecule metabolic process; GO:0051806 entry into cell of other organism involved in symbiotic interaction; GO:0019058 viral life cycle; GO:0030193 regulation of blood coagulation; GO:0009988 cell-cell recognition; GO:0080134 regulation of response to stress; GO:0050896 response to stimulus; GO:0008037 cell recognition; GO:0019062 virion attachment to host cell; GO:0051239 regulation of multicellular organismal process; GO:0045087 innate immune response; GO:0051817 modification of morphology or physiology of other organism involved in symbiotic interaction; GO:0016032 viral process; GO:0044406 adhesion of symbiont to host; GO:0009987 cellular process; GO:0050878 regulation of body fluid levels; GO:0046794 transport of virus; GO:0006950 response to stress; GO:0035556 intracellular signal transduction; GO:0016192 vesicle-mediated transport; GO:0071702 organic substance transport; GO:0002376 immune system process; GO:0032101 regulation of response to external stimulus; GO:0051701 interaction with host; GO:0006897 endocytosis; GO:0051641 cellular localization; GO:0044766 multi-organism transport; GO:0050818 regulation of coagulation; GO:0019882 antigen processing and presentation; GO:0061041 regulation of wound healing; GO:0051179 localization; GO:0044650 adhesion of symbiont to host cell; GO:0006955 immune response; GO:0019048 modulation by virus of host morphology or physiology; GO:1903034 regulation of response to wounding; GO:0071705 nitrogen compound transport; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0031226 intrinsic component of plasma membrane; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0044459 plasma membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; ","GO:0038023 signaling receptor activity; GO:0043167 ion binding; GO:0005515 protein binding; GO:0033218 amide binding; GO:0048029 monosaccharide binding; GO:0004888 transmembrane signaling receptor activity; GO:0004871 signal transducer activity; GO:0048306 calcium-dependent protein binding; GO:0003823 antigen binding; GO:0001618 virus receptor activity; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0042277 peptide binding; GO:0005488 binding; GO:0005537 mannose binding; GO:0030246 carbohydrate binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0042605 peptide antigen binding; GO:0046790 virion binding; GO:0099600 transmembrane receptor activity; GO:0030369 ICAM-3 receptor activity; GO:0036094 small molecule binding; ","K06563","CD209; CD209 antigen","hsa05162 Measles - Homo sapiens (human); hsa05152 Tuberculosis - Homo sapiens (human); hsa04625 C-type lectin receptor signaling pathway - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); ","IPR001304; IPR016187; IPR033989; IPR016186; ","\"C-type lectin-like; C-type lectin fold; CD209-like, C-type lectin-like domain; C-type lectin-like/link domain; \"\r"]
["Q9H3H3","UPF0696 protein C11orf68 OS=Homo sapiens OX=9606 GN=C11orf68","C11orf68",27.354,16.484,9.2,2,4,2,1.039,0.959,1.064,0.944,0.892,0.984,0.921,0.125,"extracellular\r",null,null,"GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005515 protein binding; GO:0005488 binding; GO:0003676 nucleic acid binding; "]
["Q9H3K2","Growth hormone-inducible transmembrane protein OS=Homo sapiens OX=9606 GN=GHITM","GHITM",37.205,13.254,6.4,3,5,3,0.949,1.024,1.017,0.977,1.031,1.009,1.009,0.763,"plasma membrane\r","GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0012501 programmed cell death; GO:0009987 cellular process; GO:0008219 cell death; GO:0006915 apoptotic process; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0019866 organelle inner membrane; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031975 envelope; GO:0043230 extracellular organelle; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; "]
["Q9H3S7","Tyrosine-protein phosphatase non-receptor type 23 OS=Homo sapiens OX=9606 GN=PTPN23","PTPN23",178.97,64.704,10.8,15,16,15,0.954,1.109,0.971,1.013,1.032,0.947,0.986,0.831,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0060627 regulation of vesicle-mediated transport; GO:1903391 regulation of adherens junction organization; GO:0010633 negative regulation of epithelial cell migration; GO:0060271 cilium assembly; GO:0044699 single-organism process; GO:0051241 negative regulation of multicellular organismal process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0044782 cilium organization; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0040013 negative regulation of locomotion; GO:0008152 metabolic process; GO:1903651 positive regulation of cytoplasmic transport; GO:0022607 cellular component assembly; GO:0032879 regulation of localization; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:2000643 positive regulation of early endosome to late endosome transport; GO:0010632 regulation of epithelial cell migration; GO:1903649 regulation of cytoplasmic transport; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0032386 regulation of intracellular transport; GO:2000146 negative regulation of cell motility; GO:0051050 positive regulation of transport; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:1902589 single-organism organelle organization; GO:1903393 positive regulation of adherens junction organization; GO:0050789 regulation of biological process; GO:0030030 cell projection organization; GO:0030163 protein catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0036211 protein modification process; GO:0051271 negative regulation of cellular component movement; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0044267 cellular protein metabolic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:1903385 regulation of homophilic cell adhesion; GO:0051239 regulation of multicellular organismal process; GO:0060341 regulation of cellular localization; GO:0071704 organic substance metabolic process; GO:1903387 positive regulation of homophilic cell adhesion; GO:0070925 organelle assembly; GO:2000145 regulation of cell motility; GO:2000641 regulation of early endosome to late endosome transport; GO:0044248 cellular catabolic process; GO:0006508 proteolysis; GO:0009987 cellular process; GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; GO:0043632 modification-dependent macromolecule catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0035335 peptidyl-tyrosine dephosphorylation; GO:0045785 positive regulation of cell adhesion; GO:0019941 modification-dependent protein catabolic process; GO:0051270 regulation of cellular component movement; GO:0051049 regulation of transport; GO:0032388 positive regulation of intracellular transport; GO:0030334 regulation of cell migration; GO:0071702 organic substance transport; GO:0006470 protein dephosphorylation; GO:0044238 primary metabolic process; GO:0016311 dephosphorylation; GO:0048518 positive regulation of biological process; GO:0030155 regulation of cell adhesion; GO:0030031 cell projection assembly; GO:0045184 establishment of protein localization; GO:0006793 phosphorus metabolic process; GO:0030336 negative regulation of cell migration; GO:0006996 organelle organization; GO:0009057 macromolecule catabolic process; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0043412 macromolecule modification; GO:0040012 regulation of locomotion; GO:0009056 catabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0005654 nucleoplasm; GO:0005815 microtubule organizing center; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0044441 ciliary part; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0005929 cilium; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0036064 ciliary basal body; GO:0031981 nuclear lumen; GO:0044463 cell projection part; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0004725 protein tyrosine phosphatase activity; GO:0003824 catalytic activity; GO:0042578 phosphoric ester hydrolase activity; GO:0005488 binding; GO:0016791 phosphatase activity; GO:0019901 protein kinase binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0004721 phosphoprotein phosphatase activity; GO:0019900 kinase binding; GO:0019899 enzyme binding; ","K18040",null,null,"IPR029021; IPR000387; IPR003595; IPR000242; IPR025304; IPR004328; ","\"Protein-tyrosine phosphatase-like; Tyrosine specific protein phosphatases domain; Protein-tyrosine phosphatase, catalytic; PTP type protein phosphatase; ALIX V-shaped domain; BRO1 domain; \"\r"]
["Q9H444","Charged multivesicular body protein 4b OS=Homo sapiens OX=9606 GN=CHMP4B","CHMP4B",24.95,14.518,26.3,6,7,6,0.897,0.869,0.897,1.121,1.136,1.074,1.251,0.000361,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:0010941 regulation of cell death; GO:0065008 regulation of biological quality; GO:1902116 negative regulation of organelle assembly; GO:0006914 autophagy; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0008152 metabolic process; GO:0070972 protein localization to endoplasmic reticulum; GO:0010824 regulation of centrosome duplication; GO:0065003 macromolecular complex assembly; GO:0036258 multivesicular body assembly; GO:0044770 cell cycle phase transition; GO:0033365 protein localization to organelle; GO:0010458 exit from mitosis; GO:0051493 regulation of cytoskeleton organization; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0008104 protein localization; GO:0044419 interspecies interaction between organisms; GO:0031468 nuclear envelope reassembly; GO:0000278 mitotic cell cycle; GO:0007059 chromosome segregation; GO:0044088 regulation of vacuole organization; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0072657 protein localization to membrane; GO:1901673 regulation of mitotic spindle assembly; GO:0031329 regulation of cellular catabolic process; GO:0007088 regulation of mitotic nuclear division; GO:0009894 regulation of catabolic process; GO:0039702 viral budding via host ESCRT complex; GO:0044763 single-organism cellular process; GO:0045047 protein targeting to ER; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0010506 regulation of autophagy; GO:0051704 multi-organism process; GO:0032886 regulation of microtubule-based process; GO:0006810 transport; GO:0016241 regulation of macroautophagy; GO:1901575 organic substance catabolic process; GO:2000785 regulation of autophagosome assembly; GO:0030163 protein catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0051301 cell division; GO:0060548 negative regulation of cell death; GO:0046605 regulation of centrosome cycle; GO:0050794 regulation of cellular process; GO:0051640 organelle localization; GO:0046907 intracellular transport; GO:0044707 single-multicellular organism process; GO:0007346 regulation of mitotic cell cycle; GO:0051260 protein homooligomerization; GO:0044267 cellular protein metabolic process; GO:0090148 membrane fission; GO:0000920 cell separation after cytokinesis; GO:0007080 mitotic metaphase plate congression; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0060249 anatomical structure homeostasis; GO:0051259 protein oligomerization; GO:0000910 cytokinesis; GO:0044248 cellular catabolic process; GO:0034613 cellular protein localization; GO:0090150 establishment of protein localization to membrane; GO:0006461 protein complex assembly; GO:0044772 mitotic cell cycle phase transition; GO:1901215 negative regulation of neuron death; GO:0016192 vesicle-mediated transport; GO:0043900 regulation of multi-organism process; GO:1902188 positive regulation of viral release from host cell; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0051656 establishment of organelle localization; GO:0009892 negative regulation of metabolic process; GO:0045184 establishment of protein localization; GO:1902186 regulation of viral release from host cell; GO:0031330 negative regulation of cellular catabolic process; GO:0090224 regulation of spindle organization; GO:0061640 cytoskeleton-dependent cytokinesis; GO:0051276 chromosome organization; GO:0098813 nuclear chromosome segregation; GO:0006996 organelle organization; GO:0006900 membrane budding; GO:0061024 membrane organization; GO:0000280 nuclear division; GO:0051179 localization; GO:0010256 endomembrane system organization; GO:0072594 establishment of protein localization to organelle; GO:1902902 negative regulation of autophagosome assembly; GO:0040017 positive regulation of locomotion; GO:0051129 negative regulation of cellular component organization; GO:0007067 mitotic nuclear division; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0060236 regulation of mitotic spindle organization; GO:1902115 regulation of organelle assembly; GO:0036438 maintenance of lens transparency; GO:0048871 multicellular organismal homeostasis; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0051783 regulation of nuclear division; GO:0000819 sister chromatid segregation; GO:0050000 chromosome localization; GO:0051649 establishment of localization in cell; GO:0022607 cellular component assembly; GO:0033036 macromolecule localization; GO:0051726 regulation of cell cycle; GO:0016236 macroautophagy; GO:1903902 positive regulation of viral life cycle; GO:0043902 positive regulation of multi-organism process; GO:0071822 protein complex subunit organization; GO:0048522 positive regulation of cellular process; GO:0036257 multivesicular body organization; GO:0016197 endosomal transport; GO:0010639 negative regulation of organelle organization; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0001894 tissue homeostasis; GO:0019222 regulation of metabolic process; GO:0010507 negative regulation of autophagy; GO:0006620 posttranslational protein targeting to membrane; GO:0070271 protein complex biogenesis; GO:0016242 negative regulation of macroautophagy; GO:0006997 nucleus organization; GO:0016043 cellular component organization; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0019068 virion assembly; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0048285 organelle fission; GO:0019058 viral life cycle; GO:1902592 multi-organism membrane budding; GO:0044087 regulation of cellular component biogenesis; GO:0031324 negative regulation of cellular metabolic process; GO:0051310 metaphase plate congression; GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway; GO:0071704 organic substance metabolic process; GO:0006998 nuclear envelope organization; GO:0042592 homeostatic process; GO:0070925 organelle assembly; GO:0016032 viral process; GO:0006886 intracellular protein transport; GO:0009895 negative regulation of catabolic process; GO:0006508 proteolysis; GO:0009987 cellular process; GO:1901214 regulation of neuron death; GO:0070507 regulation of microtubule cytoskeleton organization; GO:0044265 cellular macromolecule catabolic process; GO:0044803 multi-organism membrane organization; GO:0051303 establishment of chromosome localization; GO:0050792 regulation of viral process; GO:0000281 mitotic cytokinesis; GO:0000070 mitotic sister chromatid segregation; GO:0044802 single-organism membrane organization; GO:0033043 regulation of organelle organization; GO:0016050 vesicle organization; GO:0048518 positive regulation of biological process; GO:1902590 multi-organism organelle organization; GO:0043933 macromolecular complex subunit organization; GO:0051641 cellular localization; GO:0070727 cellular macromolecule localization; GO:0090169 regulation of spindle assembly; GO:0048524 positive regulation of viral process; GO:0046755 viral budding; GO:0007034 vacuolar transport; GO:0009057 macromolecule catabolic process; GO:0051128 regulation of cellular component organization; GO:0022402 cell cycle process; GO:1903900 regulation of viral life cycle; GO:0040012 regulation of locomotion; GO:0009056 catabolic process; GO:0007032 endosome organization; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0009898 cytoplasmic side of plasma membrane; GO:0098562 cytoplasmic side of membrane; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0036452 ESCRT complex; GO:0031902 late endosome membrane; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0000815 ESCRT III complex; GO:0098552 side of membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0010008 endosome membrane; GO:0005770 late endosome; GO:0098588 bounding membrane of organelle; GO:0005635 nuclear envelope; GO:0048475 coated membrane; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0030496 midbody; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0031975 envelope; GO:0030117 membrane coat; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0050839 cell adhesion molecule binding; GO:0042802 identical protein binding; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0046983 protein dimerization activity; GO:0045296 cadherin binding; GO:0005515 protein binding; ","K12194","CHMP4; charged multivesicular body protein 4","hsa04144 Endocytosis - Homo sapiens (human); hsa04217 Necroptosis - Homo sapiens (human); "]
["Q9H4A4","Aminopeptidase B OS=Homo sapiens OX=9606 GN=RNPEP","RNPEP",72.595,104.98,30.6,18,26,18,1.039,1.017,1.029,0.969,0.963,0.942,0.932,0.00258,"nucleus\r","GO:0008217 regulation of blood pressure; GO:0065008 regulation of biological quality; GO:0006518 peptide metabolic process; GO:0003008 system process; GO:0045776 negative regulation of blood pressure; GO:0006807 nitrogen compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0032501 multicellular organismal process; GO:0071704 organic substance metabolic process; GO:1901575 organic substance catabolic process; GO:0008152 metabolic process; GO:1901565 organonitrogen compound catabolic process; GO:0043171 peptide catabolic process; GO:0008015 blood circulation; GO:0044248 cellular catabolic process; GO:0006508 proteolysis; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0003013 circulatory system process; GO:0009987 cellular process; GO:0009056 catabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016801 hydrolase activity, acting on ether bonds; GO:0008238 exopeptidase activity; GO:0008233 peptidase activity; GO:0043167 ion binding; GO:0070006 metalloaminopeptidase activity; GO:0008235 metalloexopeptidase activity; GO:0004177 aminopeptidase activity; GO:0016787 hydrolase activity; GO:0008237 metallopeptidase activity; GO:0033218 amide binding; GO:0008270 zinc ion binding; GO:0046914 transition metal ion binding; GO:0042277 peptide binding; GO:0004301 epoxide hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0016803 ether hydrolase activity; ","K01260",null,null,"IPR014782; IPR015211; IPR016024; ","\"Peptidase M1, membrane alanine aminopeptidase, N-terminal; Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal; Armadillo-type fold; \"\r"]
["Q9H4A6","Golgi phosphoprotein 3 OS=Homo sapiens OX=9606 GN=GOLPH3","GOLPH3",33.81,20.841,17.1,4,4,4,0.987,0.837,0.899,1.038,1.046,1.085,1.164,0.0363,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0010941 regulation of cell death; GO:0090002 establishment of protein localization to plasma membrane; GO:0044237 cellular metabolic process; GO:0010821 regulation of mitochondrion organization; GO:0015031 protein transport; GO:0022610 biological adhesion; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0032879 regulation of localization; GO:0007155 cell adhesion; GO:0009306 protein secretion; GO:0033365 protein localization to organelle; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0051651 maintenance of location in cell; GO:0008104 protein localization; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0030032 lamellipodium assembly; GO:0032507 maintenance of protein location in cell; GO:0072657 protein localization to membrane; GO:0050901 leukocyte tethering or rolling; GO:0044763 single-organism cellular process; GO:0009100 glycoprotein metabolic process; GO:0007163 establishment or maintenance of cell polarity; GO:0007009 plasma membrane organization; GO:0048870 cell motility; GO:0006810 transport; GO:0050900 leukocyte migration; GO:0007030 Golgi organization; GO:0048583 regulation of response to stimulus; GO:0050714 positive regulation of protein secretion; GO:0098602 single organism cell adhesion; GO:0044260 cellular macromolecule metabolic process; GO:0051223 regulation of protein transport; GO:0060548 negative regulation of cell death; GO:0051047 positive regulation of secretion; GO:0050794 regulation of cellular process; GO:0043067 regulation of programmed cell death; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:1990778 protein localization to cell periphery; GO:1902578 single-organism localization; GO:1901135 carbohydrate derivative metabolic process; GO:1902580 single-organism cellular localization; GO:0032880 regulation of protein localization; GO:0034613 cellular protein localization; GO:0009966 regulation of signal transduction; GO:0090150 establishment of protein localization to membrane; GO:1902531 regulation of intracellular signal transduction; GO:0061756 leukocyte adhesion to vascular endothelial cell; GO:0016192 vesicle-mediated transport; GO:0008283 cell proliferation; GO:0002376 immune system process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0030031 cell projection assembly; GO:0045184 establishment of protein localization; GO:0072659 protein localization to plasma membrane; GO:1904951 positive regulation of establishment of protein localization; GO:0006996 organelle organization; GO:0045123 cellular extravasation; GO:0061024 membrane organization; GO:0006900 membrane budding; GO:0006928 movement of cell or subcellular component; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0006892 post-Golgi vesicle-mediated transport; GO:0090164 asymmetric Golgi ribbon formation; GO:0097581 lamellipodium organization; GO:0010256 endomembrane system organization; GO:0051674 localization of cell; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0051046 regulation of secretion; GO:0009058 biosynthetic process; GO:0051234 establishment of localization; GO:0016337 single organismal cell-cell adhesion; GO:0010646 regulation of cell communication; GO:0022607 cellular component assembly; GO:0006893 Golgi to plasma membrane transport; GO:0060352 cell adhesion molecule production; GO:0048194 Golgi vesicle budding; GO:0033036 macromolecule localization; GO:0009101 glycoprotein biosynthetic process; GO:0090162 establishment of epithelial cell polarity; GO:0098609 cell-cell adhesion; GO:0048522 positive regulation of cellular process; GO:0045053 protein retention in Golgi apparatus; GO:1903530 regulation of secretion by cell; GO:0051050 positive regulation of transport; GO:0050789 regulation of biological process; GO:0030030 cell projection organization; GO:1903532 positive regulation of secretion by cell; GO:0032940 secretion by cell; GO:0040011 locomotion; GO:0051222 positive regulation of protein transport; GO:0016043 cellular component organization; GO:0016477 cell migration; GO:0007159 leukocyte cell-cell adhesion; GO:0043069 negative regulation of programmed cell death; GO:0048193 Golgi vesicle transport; GO:0090161 Golgi ribbon formation; GO:0070201 regulation of establishment of protein localization; GO:0071704 organic substance metabolic process; GO:0032006 regulation of TOR signaling; GO:0043066 negative regulation of apoptotic process; GO:0023056 positive regulation of signaling; GO:0030010 establishment of cell polarity; GO:0043001 Golgi to plasma membrane protein transport; GO:0010647 positive regulation of cell communication; GO:0051235 maintenance of location; GO:0050708 regulation of protein secretion; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0034067 protein localization to Golgi apparatus; GO:0098876 vesicle-mediated transport to the plasma membrane; GO:0045185 maintenance of protein location; GO:0032008 positive regulation of TOR signaling; GO:0051049 regulation of transport; GO:0044802 single-organism membrane organization; GO:0016050 vesicle organization; GO:0033043 regulation of organelle organization; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0070727 cellular macromolecule localization; GO:0034645 cellular macromolecule biosynthetic process; GO:0006890 retrograde vesicle-mediated transport, Golgi to ER; GO:0010467 gene expression; GO:0051128 regulation of cellular component organization; GO:0009967 positive regulation of signal transduction; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0005740 mitochondrial envelope; GO:0070013 intracellular organelle lumen; GO:0031970 organelle envelope lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0098791 Golgi subcompartment; GO:0044431 Golgi apparatus part; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0032580 Golgi cisterna membrane; GO:0044429 mitochondrial part; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0005795 Golgi stack; GO:0005829 cytosol; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005758 mitochondrial intermembrane space; GO:0031975 envelope; GO:0005802 trans-Golgi network; GO:0005794 Golgi apparatus; GO:0031985 Golgi cisterna; GO:0044444 cytoplasmic part; GO:0031984 organelle subcompartment; ","GO:1901981 phosphatidylinositol phosphate binding; GO:0005488 binding; GO:0005543 phospholipid binding; GO:0035091 phosphatidylinositol binding; GO:0043167 ion binding; GO:0008289 lipid binding; GO:0043168 anion binding; GO:0005515 protein binding; GO:0070273 phosphatidylinositol-4-phosphate binding; GO:0019899 enzyme binding; ","K15620"]
["Q9H5N1","Rab GTPase-binding effector protein 2 OS=Homo sapiens OX=9606 GN=RABEP2","RABEP2",63.542,9.3151,8.4,4,4,4,0.953,1.126,0.98,0.969,1.008,0.976,0.965,0.57,"nucleus\r","GO:0043547 positive regulation of GTPase activity; GO:0016192 vesicle-mediated transport; GO:0071702 organic substance transport; GO:0006897 endocytosis; GO:0015031 protein transport; GO:0043085 positive regulation of catalytic activity; GO:0051234 establishment of localization; GO:0006810 transport; GO:0045184 establishment of protein localization; GO:0051336 regulation of hydrolase activity; GO:0051345 positive regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0044093 positive regulation of molecular function; GO:0065009 regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0051179 localization; GO:0065007 biological regulation; ","GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005769 early endosome; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005622 intracellular; GO:0044464 cell part; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0008083 growth factor activity; GO:0030234 enzyme regulator activity; GO:0005102 receptor binding; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0005488 binding; GO:0030695 GTPase regulator activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0008047 enzyme activator activity; GO:0005096 GTPase activator activity; ","K20130",null,null,"IPR015390; IPR018514; ","\"Rabaptin, GTPase-Rab5 binding domain; Rabaptin coiled-coil domain; \"\r"]
["Q9H6B9","Epoxide hydrolase 3 OS=Homo sapiens OX=9606 GN=EPHX3","EPHX3",40.908,7.8534,8.1,3,3,3,0.898,0.902,0.852,1.26,1.128,0.962,1.263,0.0472,"mitochondria\r",null,"GO:0005576 extracellular region; ","GO:0016787 hydrolase activity; GO:0003824 catalytic activity; ",{"$nulls":3},"IPR029058; IPR000073; ","Alpha/Beta hydrolase fold; Alpha/beta hydrolase fold-1; \r"]
["Q9H6S0","Probable ATP-dependent RNA helicase YTHDC2 OS=Homo sapiens OX=9606 GN=YTHDC2","YTHDC2",160.25,2.2731,0.6,1,1,1,0.887,0.945,0.854,1.056,1.193,1.06,1.232,0.014,"nucleus\r","GO:0050794 regulation of cellular process; GO:0065008 regulation of biological quality; GO:0044827 modulation by host of viral genome replication; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0006725 cellular aromatic compound metabolic process; GO:0070555 response to interleukin-1; GO:0035821 modification of morphology or physiology of other organism; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0051817 modification of morphology or physiology of other organism involved in symbiotic interaction; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0051702 interaction with symbiont; GO:0034641 cellular nitrogen compound metabolic process; GO:0034612 response to tumor necrosis factor; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0045070 positive regulation of viral genome replication; GO:0009987 cellular process; GO:0006396 RNA processing; GO:1903902 positive regulation of viral life cycle; GO:0044794 positive regulation by host of viral process; GO:0043902 positive regulation of multi-organism process; GO:0034097 response to cytokine; GO:0043900 regulation of multi-organism process; GO:0050792 regulation of viral process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0044829 positive regulation by host of viral genome replication; GO:0045069 regulation of viral genome replication; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0044788 modulation by host of viral process; GO:0048518 positive regulation of biological process; GO:0051704 multi-organism process; GO:0016070 RNA metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0048524 positive regulation of viral process; GO:0090304 nucleic acid metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:1903900 regulation of viral life cycle; GO:0051851 modification by host of symbiont morphology or physiology; GO:0065007 biological regulation; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005783 endoplasmic reticulum; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0008026 ATP-dependent helicase activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0070063 RNA polymerase binding; GO:0016887 ATPase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0004004 ATP-dependent RNA helicase activity; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003723 RNA binding; GO:0070035 purine NTP-dependent helicase activity; GO:0005524 ATP binding; GO:0004386 helicase activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0008186 RNA-dependent ATPase activity; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:1990247 N6-methyladenosine-containing RNA binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003724 RNA helicase activity; GO:0003676 nucleic acid binding; GO:0042623 ATPase activity, coupled; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019899 enzyme binding; GO:0036094 small molecule binding; ","K20099",null,null,"IPR007502; IPR011545; IPR029058; IPR011709; IPR027417; IPR001374; IPR034083; IPR020683; IPR014001; IPR007275; IPR001650; ","\"Helicase-associated domain; DEAD/DEAH box helicase domain; Alpha/Beta hydrolase fold; Domain of unknown function DUF1605; P-loop containing nucleoside triphosphate hydrolase; R3H domain; DExH-box ATP-dependent RNA helicase, R3H domain; Ankyrin repeat-containing domain; Helicase superfamily 1/2, ATP-binding domain; YTH domain; Helicase, C-terminal; \"\r"]
["Q9H6Z4","Ran-binding protein 3 OS=Homo sapiens OX=9606 GN=RANBP3","RANBP3",60.209,25.81,11.8,6,7,6,0.998,0.941,0.965,0.985,0.999,1.059,1.048,0.171,"nucleus\r","GO:0050658 RNA transport; GO:0072594 establishment of protein localization to organelle; GO:0017038 protein import; GO:0051785 positive regulation of nuclear division; GO:0044699 single-organism process; GO:0051169 nuclear transport; GO:0051168 nuclear export; GO:0044237 cellular metabolic process; GO:0010564 regulation of cell cycle process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0051130 positive regulation of cellular component organization; GO:0008152 metabolic process; GO:0051783 regulation of nuclear division; GO:0051649 establishment of localization in cell; GO:0050657 nucleic acid transport; GO:0015931 nucleobase-containing compound transport; GO:0044093 positive regulation of molecular function; GO:0044770 cell cycle phase transition; GO:0033365 protein localization to organelle; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0051493 regulation of cytoskeleton organization; GO:0006606 protein import into nucleus; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0090068 positive regulation of cell cycle process; GO:0051726 regulation of cell cycle; GO:0044765 single-organism transport; GO:0000278 mitotic cell cycle; GO:0046604 positive regulation of mitotic centrosome separation; GO:0007088 regulation of mitotic nuclear division; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:1902582 single-organism intracellular transport; GO:0045840 positive regulation of mitotic nuclear division; GO:0006810 transport; GO:0032886 regulation of microtubule-based process; GO:1901575 organic substance catabolic process; GO:0000226 microtubule cytoskeleton organization; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:0045931 positive regulation of mitotic cell cycle; GO:0010638 positive regulation of organelle organization; GO:0030163 protein catabolic process; GO:0050790 regulation of catalytic activity; GO:0046602 regulation of mitotic centrosome separation; GO:0044260 cellular macromolecule metabolic process; GO:0043087 regulation of GTPase activity; GO:0065009 regulation of molecular function; GO:0006913 nucleocytoplasmic transport; GO:0046605 regulation of centrosome cycle; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0007346 regulation of mitotic cell cycle; GO:0044257 cellular protein catabolic process; GO:1902593 single-organism nuclear import; GO:0044267 cellular protein metabolic process; GO:0007051 spindle organization; GO:1903047 mitotic cell cycle process; GO:0051236 establishment of RNA localization; GO:0071704 organic substance metabolic process; GO:1902578 single-organism localization; GO:0051345 positive regulation of hydrolase activity; GO:0006886 intracellular protein transport; GO:0044744 protein targeting to nucleus; GO:0044248 cellular catabolic process; GO:1902580 single-organism cellular localization; GO:0006508 proteolysis; GO:0034613 cellular protein localization; GO:0000082 G1/S transition of mitotic cell cycle; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0044772 mitotic cell cycle phase transition; GO:0045787 positive regulation of cell cycle; GO:0043632 modification-dependent macromolecule catabolic process; GO:0070507 regulation of microtubule cytoskeleton organization; GO:0044265 cellular macromolecule catabolic process; GO:0051495 positive regulation of cytoskeleton organization; GO:0044843 cell cycle G1/S phase transition; GO:0019941 modification-dependent protein catabolic process; GO:0043547 positive regulation of GTPase activity; GO:0046607 positive regulation of centrosome cycle; GO:0006403 RNA localization; GO:0006405 RNA export from nucleus; GO:0033043 regulation of organelle organization; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0007017 microtubule-based process; GO:0051641 cellular localization; GO:0043085 positive regulation of catalytic activity; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0051170 nuclear import; GO:0006996 organelle organization; GO:0009057 macromolecule catabolic process; GO:0051128 regulation of cellular component organization; GO:0022402 cell cycle process; GO:0051179 localization; GO:0034504 protein localization to nucleus; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0071705 nitrogen compound transport; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031974 membrane-enclosed lumen; GO:0005815 microtubule organizing center; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0005813 centrosome; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0031267 small GTPase binding; GO:0017016 Ras GTPase binding; GO:0005488 binding; GO:0005515 protein binding; GO:0008536 Ran GTPase binding; GO:0070412 R-SMAD binding; GO:0051020 GTPase binding; GO:0046332 SMAD binding; GO:0019899 enzyme binding; ","K15304","RANBP3; Ran-binding protein 3","hsa05166 HTLV-I infection - Homo sapiens (human); ","IPR000156; IPR011993; ","Ran binding domain; PH domain-like; \r"]
["Q9H7C9","Mth938 domain-containing protein OS=Homo sapiens OX=9606 GN=AAMDC","AAMDC",13.332,15.381,33.6,4,5,4,0.972,1.11,1.038,1.001,0.984,0.952,0.941,0.223,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0010941 regulation of cell death; GO:0043069 negative regulation of programmed cell death; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0043067 regulation of programmed cell death; GO:0009891 positive regulation of biosynthetic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0045597 positive regulation of cell differentiation; GO:2001141 regulation of RNA biosynthetic process; GO:0045600 positive regulation of fat cell differentiation; GO:0043066 negative regulation of apoptotic process; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0045595 regulation of cell differentiation; GO:0010468 regulation of gene expression; GO:0051254 positive regulation of RNA metabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0048522 positive regulation of cellular process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:1903506 regulation of nucleic acid-templated transcription; GO:0045598 regulation of fat cell differentiation; GO:0050789 regulation of biological process; GO:0031325 positive regulation of cellular metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0019222 regulation of metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0060548 negative regulation of cell death; GO:0050793 regulation of developmental process; GO:0051094 positive regulation of developmental process; GO:0042981 regulation of apoptotic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0065007 biological regulation; ","GO:0044424 intracellular part; GO:0005623 cell; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; ","GO:0005515 protein binding; GO:0005488 binding; "]
["Q9H7D7","WD repeat-containing protein 26 OS=Homo sapiens OX=9606 GN=WDR26","WDR26",72.123,4.1534,2.9,2,2,2,0.918,0.982,0.994,1.066,1.074,0.971,1.075,0.153,"nucleus\r",null,"GO:0043229 intracellular organelle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR017986; IPR015943; IPR006595; IPR006594; ","\"WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain; CTLH, C-terminal LisH motif; LIS1 homology motif; \"\r"]
["Q9H832","Ubiquitin-conjugating enzyme E2 Z OS=Homo sapiens OX=9606 GN=UBE2Z","UBE2Z",38.21,19.263,18.9,6,6,6,1.014,0.884,0.985,1.1,0.952,1.069,1.083,0.263,"nucleus\r","GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0006915 apoptotic process; GO:0044248 cellular catabolic process; GO:0006508 proteolysis; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0009987 cellular process; GO:0043632 modification-dependent macromolecule catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0016567 protein ubiquitination; GO:0019941 modification-dependent protein catabolic process; GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0044763 single-organism cellular process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0044238 primary metabolic process; GO:1901575 organic substance catabolic process; GO:0032446 protein modification by small protein conjugation; GO:0008219 cell death; GO:0030163 protein catabolic process; GO:0009057 macromolecule catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0012501 programmed cell death; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:0009056 catabolic process; ","GO:0043229 intracellular organelle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0031625 ubiquitin protein ligase binding; GO:0005515 protein binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0061630 ubiquitin protein ligase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0019787 ubiquitin-like protein transferase activity; GO:0061631 ubiquitin conjugating enzyme activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0061659 ubiquitin-like protein ligase activity; GO:0000166 nucleotide binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0004842 ubiquitin-protein transferase activity; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0061650 ubiquitin-like protein conjugating enzyme activity; GO:0044389 ubiquitin-like protein ligase binding; GO:0019899 enzyme binding; GO:0036094 small molecule binding; ","K10585","UBE2Z; ubiquitin-conjugating enzyme E2 Z [EC:2.3.2.23]","hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human); ","IPR016135; IPR000608; ","Ubiquitin-conjugating enzyme/RWD-like; Ubiquitin-conjugating enzyme E2; \r"]
["Q9H8M7","Ubiquitin carboxyl-terminal hydrolase MINDY-3 OS=Homo sapiens OX=9606 GN=MINDY3","MINDY3",49.724,14.823,5.6,2,2,2,0.897,0.849,1.094,1.064,0.98,1.113,1.112,0.266,"nucleus\r","GO:0071108 protein K48-linked deubiquitination; GO:0070646 protein modification by small protein removal; GO:0044763 single-organism cellular process; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0070647 protein modification by small protein conjugation or removal; GO:0044238 primary metabolic process; GO:0016579 protein deubiquitination; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0008219 cell death; GO:0006915 apoptotic process; GO:0044260 cellular macromolecule metabolic process; GO:0006508 proteolysis; GO:0006464 cellular protein modification process; GO:0012501 programmed cell death; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:0009987 cellular process; ","GO:0016020 membrane; GO:0043229 intracellular organelle; GO:0031090 organelle membrane; GO:0005635 nuclear envelope; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005654 nucleoplasm; GO:0031965 nuclear membrane; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0031975 envelope; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0004180 carboxypeptidase activity; GO:0008238 exopeptidase activity; GO:0008233 peptidase activity; GO:0036459 thiol-dependent ubiquitinyl hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0101005 ubiquitinyl hydrolase activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0019783 ubiquitin-like protein-specific protease activity; GO:0005515 protein binding; GO:0008234 cysteine-type peptidase activity; GO:0016787 hydrolase activity; GO:0016807 cysteine-type carboxypeptidase activity; GO:1990380 Lys48-specific deubiquitinase activity; GO:0070004 cysteine-type exopeptidase activity; ",{"$nulls":3},"IPR025257; IPR011992; ","Domain of unknown function DUF4205; EF-hand domain pair; \r"]
["Q9H8Y8","Golgi reassembly-stacking protein 2 OS=Homo sapiens OX=9606 GN=GORASP2","GORASP2",47.145,7.6511,8.6,5,6,5,0.968,1.052,0.997,0.964,1.016,1.031,0.998,0.957,"nucleus\r","GO:0016043 cellular component organization; GO:0010256 endomembrane system organization; GO:0007030 Golgi organization; GO:0009987 cellular process; GO:0006996 organelle organization; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0098588 bounding membrane of organelle; GO:0031090 organelle membrane; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005622 intracellular; GO:0044464 cell part; GO:0044431 Golgi apparatus part; GO:0005794 Golgi apparatus; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR024958; IPR001478; ","GRASP55/65 PDZ-like domain; PDZ domain; \r"]
["Q9H993","Protein-glutamate O-methyltransferase OS=Homo sapiens OX=9606 GN=ARMT1","ARMT1",51.172,28.659,7.7,3,4,3,1.012,1.011,1.038,1.026,0.968,0.958,0.964,0.187,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0051716 cellular response to stimulus; GO:0006950 response to stress; GO:2001020 regulation of response to DNA damage stimulus; GO:0044267 cellular protein metabolic process; GO:0080134 regulation of response to stress; GO:0050896 response to stimulus; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0006974 cellular response to DNA damage stimulus; GO:0032259 methylation; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0008213 protein alkylation; GO:0050789 regulation of biological process; GO:0080135 regulation of cellular response to stress; GO:0006479 protein methylation; GO:0043414 macromolecule methylation; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:0009987 cellular process; GO:0065007 biological regulation; ",null,"GO:0008757 S-adenosylmethionine-dependent methyltransferase activity; GO:0008168 methyltransferase activity; GO:0008276 protein methyltransferase activity; GO:0010340 carboxyl-O-methyltransferase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0051998 protein carboxyl O-methyltransferase activity; GO:0016741 transferase activity, transferring one-carbon groups; GO:0005515 protein binding; GO:0008171 O-methyltransferase activity; GO:0016740 transferase activity; GO:0019899 enzyme binding; ",{"$nulls":3},"IPR002791; ","Domain of unknown function DUF89; \r"]
["Q9H9A5","CCR4-NOT transcription complex subunit 10 OS=Homo sapiens OX=9606 GN=CNOT10","CNOT10",82.309,7.9935,3.4,2,2,2,0.761,0.836,0.804,1.038,1.293,1.245,1.489,0.0057,"cyto_nucl\r","GO:0044700 single organism signaling; GO:1902807 negative regulation of cell cycle G1/S phase transition; GO:0010608 posttranscriptional regulation of gene expression; GO:0097659 nucleic acid-templated transcription; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0072431 signal transduction involved in mitotic G1 DNA damage checkpoint; GO:1902403 signal transduction involved in mitotic DNA integrity checkpoint; GO:0008152 metabolic process; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0043170 macromolecule metabolic process; GO:0090068 positive regulation of cell cycle process; GO:0051716 cellular response to stimulus; GO:0000278 mitotic cell cycle; GO:0018130 heterocycle biosynthetic process; GO:0044773 mitotic DNA damage checkpoint; GO:0080090 regulation of primary metabolic process; GO:2000134 negative regulation of G1/S transition of mitotic cell cycle; GO:0044763 single-organism cellular process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0010948 negative regulation of cell cycle process; GO:0072413 signal transduction involved in mitotic cell cycle checkpoint; GO:0031047 gene silencing by RNA; GO:1902400 intracellular signal transduction involved in G1 DNA damage checkpoint; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0007346 regulation of mitotic cell cycle; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0030330 DNA damage response, signal transduction by p53 class mediator; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1902402 signal transduction involved in mitotic DNA damage checkpoint; GO:1901987 regulation of cell cycle phase transition; GO:0009889 regulation of biosynthetic process; GO:0044819 mitotic G1/S transition checkpoint; GO:0007093 mitotic cell cycle checkpoint; GO:0051171 regulation of nitrogen compound metabolic process; GO:0044248 cellular catabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0045787 positive regulation of cell cycle; GO:0006950 response to stress; GO:0072331 signal transduction by p53 class mediator; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0006974 cellular response to DNA damage stimulus; GO:0034248 regulation of cellular amide metabolic process; GO:2000045 regulation of G1/S transition of mitotic cell cycle; GO:0044783 G1 DNA damage checkpoint; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:2001141 regulation of RNA biosynthetic process; GO:0045930 negative regulation of mitotic cell cycle; GO:0007165 signal transduction; GO:0000077 DNA damage checkpoint; GO:0044774 mitotic DNA integrity checkpoint; GO:0007154 cell communication; GO:1901991 negative regulation of mitotic cell cycle phase transition; GO:1902806 regulation of cell cycle G1/S phase transition; GO:0000075 cell cycle checkpoint; GO:1901361 organic cyclic compound catabolic process; GO:0051726 regulation of cell cycle; GO:0031571 mitotic G1 DNA damage checkpoint; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0031570 DNA integrity checkpoint; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0016070 RNA metabolic process; GO:0006401 RNA catabolic process; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0090304 nucleic acid metabolic process; GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; GO:0006351 transcription, DNA-templated; GO:0019222 regulation of metabolic process; GO:0072401 signal transduction involved in DNA integrity checkpoint; GO:0072395 signal transduction involved in cell cycle checkpoint; GO:0045786 negative regulation of cell cycle; GO:0006725 cellular aromatic compound metabolic process; GO:1901988 negative regulation of cell cycle phase transition; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0042770 signal transduction in response to DNA damage; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0071156 regulation of cell cycle arrest; GO:0006355 regulation of transcription, DNA-templated; GO:0072422 signal transduction involved in DNA damage checkpoint; GO:0010629 negative regulation of gene expression; GO:0035556 intracellular signal transduction; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0016458 gene silencing; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0051246 regulation of protein metabolic process; GO:0006417 regulation of translation; GO:0009057 macromolecule catabolic process; GO:0071158 positive regulation of cell cycle arrest; GO:0010467 gene expression; GO:0022402 cell cycle process; GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0065007 biological regulation; GO:0046700 heterocycle catabolic process; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:0030014 CCR4-NOT complex; GO:0043227 membrane-bounded organelle; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ","K12607","CNOT10; CCR4-NOT transcription complex subunit 10","hsa03018 RNA degradation - Homo sapiens (human); ","IPR011990; ","Tetratricopeptide-like helical domain; \r"]
["Q9H9E3","Conserved oligomeric Golgi complex subunit 4 OS=Homo sapiens OX=9606 GN=COG4","COG4",89.082,1.7467,1.4,1,1,1,1.04,1.038,0.904,0.965,1.097,0.965,1.015,0.821,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0010256 endomembrane system organization; GO:0048193 Golgi vesicle transport; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0051649 establishment of localization in cell; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0043623 cellular protein complex assembly; GO:0034622 cellular macromolecular complex assembly; GO:0071822 protein complex subunit organization; GO:0006891 intra-Golgi vesicle-mediated transport; GO:0016192 vesicle-mediated transport; GO:0000301 retrograde transport, vesicle recycling within Golgi; GO:0071702 organic substance transport; GO:0043933 macromolecular complex subunit organization; GO:0051641 cellular localization; GO:0006810 transport; GO:0045184 establishment of protein localization; GO:0048213 Golgi vesicle prefusion complex stabilization; GO:0007030 Golgi organization; GO:0006890 retrograde vesicle-mediated transport, Golgi to ER; GO:0006996 organelle organization; GO:0070271 protein complex biogenesis; GO:0051179 localization; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0098588 bounding membrane of organelle; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0032991 macromolecular complex; GO:0012505 endomembrane system; GO:0032588 trans-Golgi network membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0098791 Golgi subcompartment; GO:0005802 trans-Golgi network; GO:0044431 Golgi apparatus part; GO:0017119 Golgi transport complex; GO:0043234 protein complex; GO:0005794 Golgi apparatus; GO:0043227 membrane-bounded organelle; GO:0031984 organelle subcompartment; GO:0044444 cytoplasmic part; GO:0099023 tethering complex; ","GO:0005515 protein binding; GO:0005488 binding; ","K20291",null,null,"IPR013167; ","\"Conserved oligomeric Golgi complex, subunit 4; \"\r"]
["Q9HA64","Ketosamine-3-kinase OS=Homo sapiens OX=9606 GN=FN3KRP","FN3KRP",34.412,30.878,33.7,9,12,9,1.021,1.057,1.011,0.997,0.932,1.037,0.96,0.29,"cytoplasm\r","GO:0043687 post-translational protein modification; GO:0016310 phosphorylation; GO:0044267 cellular protein metabolic process; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0006793 phosphorus metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:0009987 cellular process; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:0016301 kinase activity; GO:0003824 catalytic activity; GO:0016740 transferase activity; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K15523",null,null,"IPR011009; ","Protein kinase-like domain; \r"]
["Q9HA77","Probable cysteine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=CARS2","CARS2",62.223,7.96,5.1,2,2,2,0.966,1.035,1.164,0.95,0.965,0.932,0.9,0.136,"mitochondria\r","GO:0006518 peptide metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0006423 cysteinyl-tRNA aminoacylation; GO:1901566 organonitrogen compound biosynthetic process; GO:0043039 tRNA aminoacylation; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0006418 tRNA aminoacylation for protein translation; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0006412 translation; GO:0009987 cellular process; GO:0043043 peptide biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0016070 RNA metabolic process; GO:0006399 tRNA metabolic process; GO:0090304 nucleic acid metabolic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0044710 single-organism metabolic process; GO:0043038 amino acid activation; GO:0019752 carboxylic acid metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0006082 organic acid metabolic process; GO:0034660 ncRNA metabolic process; GO:0043436 oxoacid metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds; GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0016875 ligase activity, forming carbon-oxygen bonds; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016874 ligase activity; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0004817 cysteine-tRNA ligase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0004812 aminoacyl-tRNA ligase activity; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K01883","CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]","hsa00970 Aminoacyl-tRNA biosynthesis - Homo sapiens (human); ","IPR014729; IPR032678; IPR009080; ","\"Rossmann-like alpha/beta/alpha sandwich fold; tRNA synthetases class I, catalytic domain; Aminoacyl-tRNA synthetase, class Ia, anticodon-binding; \"\r"]
["Q9HAU5","Regulator of nonsense transcripts 2 OS=Homo sapiens OX=9606 GN=UPF2","UPF2",147.81,6.3715,1.7,2,2,2,1.058,0.861,1.157,0.952,1.119,0.858,0.952,0.705,"cyto_nucl\r","GO:0050658 RNA transport; GO:0031100 animal organ regeneration; GO:0048732 gland development; GO:0044699 single-organism process; GO:0051169 nuclear transport; GO:0051168 nuclear export; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0071427 mRNA-containing ribonucleoprotein complex export from nucleus; GO:0051649 establishment of localization in cell; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0050657 nucleic acid transport; GO:0015931 nucleobase-containing compound transport; GO:1901361 organic cyclic compound catabolic process; GO:0043170 macromolecule metabolic process; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:1901360 organic cyclic compound metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0006611 protein export from nucleus; GO:0032501 multicellular organismal process; GO:0071166 ribonucleoprotein complex localization; GO:0016070 RNA metabolic process; GO:0006401 RNA catabolic process; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006913 nucleocytoplasmic transport; GO:0016071 mRNA metabolic process; GO:0048856 anatomical structure development; GO:0044707 single-multicellular organism process; GO:0046907 intracellular transport; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0051028 mRNA transport; GO:0048519 negative regulation of biological process; GO:0051236 establishment of RNA localization; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0006886 intracellular protein transport; GO:0044248 cellular catabolic process; GO:0061008 hepaticobiliary system development; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0034655 nucleobase-containing compound catabolic process; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0006406 mRNA export from nucleus; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0048731 system development; GO:0006403 RNA localization; GO:0006405 RNA export from nucleus; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0001889 liver development; GO:0071426 ribonucleoprotein complex export from nucleus; GO:0044767 single-organism developmental process; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0031099 regeneration; GO:0051179 localization; GO:0009056 catabolic process; GO:0071705 nitrogen compound transport; GO:0065007 biological regulation; GO:0046700 heterocycle catabolic process; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0000932 P-body; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0043228 non-membrane-bounded organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:0035770 ribonucleoprotein granule; GO:0048471 perinuclear region of cytoplasm; GO:1990904 ribonucleoprotein complex; GO:0043234 protein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0035145 exon-exon junction complex; GO:0044444 cytoplasmic part; GO:0005844 polysome; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003677 DNA binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0042162 telomeric DNA binding; GO:0005515 protein binding; GO:0043565 sequence-specific DNA binding; ","K14327","UPF2; regulator of nonsense transcripts 2","hsa03015 mRNA surveillance pathway - Homo sapiens (human); hsa03013 RNA transport - Homo sapiens (human); ","IPR003890; IPR016024; IPR007193; IPR016021; ","\"MIF4G-like, type 3; Armadillo-type fold; Up-frameshift suppressor 2; MIF4G-like domain; \"\r"]
["Q9HAV7","GrpE protein homolog 1, mitochondrial OS=Homo sapiens OX=9606 GN=GRPEL1","GRPEL1",24.279,8.6573,12.9,3,4,3,1.027,0.91,0.926,1.05,1.076,1.02,1.099,0.0793,"mitochondria\r","GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0072594 establishment of protein localization to organelle; GO:0017038 protein import; GO:0006839 mitochondrial transport; GO:0044699 single-organism process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006457 protein folding; GO:0006605 protein targeting; GO:0051649 establishment of localization in cell; GO:1902578 single-organism localization; GO:1990542 mitochondrial transmembrane transport; GO:0007005 mitochondrion organization; GO:0065002 intracellular protein transmembrane transport; GO:0006886 intracellular protein transport; GO:0006626 protein targeting to mitochondrion; GO:1902580 single-organism cellular localization; GO:0033365 protein localization to organelle; GO:0044743 protein transmembrane import into intracellular organelle; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0044765 single-organism transport; GO:0030150 protein import into mitochondrial matrix; GO:0071806 protein transmembrane transport; GO:0071702 organic substance transport; GO:0070585 protein localization to mitochondrion; GO:1902582 single-organism intracellular transport; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:0055085 transmembrane transport; GO:0070727 cellular macromolecule localization; GO:0006996 organelle organization; GO:0050790 regulation of catalytic activity; GO:0065009 regulation of molecular function; GO:0051179 localization; GO:0072655 establishment of protein localization to mitochondrion; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0005744 mitochondrial inner membrane presequence translocase complex; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005759 mitochondrial matrix; GO:0044429 mitochondrial part; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0031975 envelope; GO:0001405 presequence translocase-associated import motor; GO:0043234 protein complex; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0051087 chaperone binding; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0098772 molecular function regulator; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0042802 identical protein binding; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0042803 protein homodimerization activity; GO:0051082 unfolded protein binding; GO:0030554 adenyl nucleotide binding; GO:0060590 ATPase regulator activity; GO:0000774 adenyl-nucleotide exchange factor activity; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; ","K03687",null,null,"IPR013805; IPR009012; ","\"GrpE nucleotide exchange factor, coiled-coil; GrpE nucleotide exchange factor, head; \"\r"]
["Q9HB07","UPF0160 protein MYG1, mitochondrial OS=Homo sapiens OX=9606 GN=C12orf10","C12orf10",42.449,28.063,13.6,4,4,4,0.965,1.048,0.81,1.057,1.083,1.043,1.128,0.243,"mitochondria\r","GO:0007610 behavior; GO:0035641 locomotory exploration behavior; GO:0044699 single-organism process; GO:0043473 pigmentation; GO:0007626 locomotory behavior; GO:0035640 exploration behavior; GO:0044708 single-organism behavior; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; "]
["Q9HB40","Retinoid-inducible serine carboxypeptidase OS=Homo sapiens OX=9606 GN=SCPEP1","SCPEP1",50.83,24.796,10.6,4,5,4,1.069,1.012,1.081,0.946,0.963,0.941,0.901,0.00862,"extracellular\r","GO:0008217 regulation of blood pressure; GO:0065008 regulation of biological quality; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0050880 regulation of blood vessel size; GO:0042573 retinoic acid metabolic process; GO:0045776 negative regulation of blood pressure; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0003018 vascular process in circulatory system; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0097746 regulation of blood vessel diameter; GO:0008152 metabolic process; GO:0008015 blood circulation; GO:0001523 retinoid metabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0044248 cellular catabolic process; GO:0006508 proteolysis; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0035150 regulation of tube size; GO:0009987 cellular process; GO:0006629 lipid metabolic process; GO:0006720 isoprenoid metabolic process; GO:0042445 hormone metabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0003008 system process; GO:0097755 positive regulation of blood vessel diameter; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0044238 primary metabolic process; GO:0032501 multicellular organismal process; GO:0035296 regulation of tube diameter; GO:0034754 cellular hormone metabolic process; GO:1901575 organic substance catabolic process; GO:0044710 single-organism metabolic process; GO:0030163 protein catabolic process; GO:0009057 macromolecule catabolic process; GO:0019752 carboxylic acid metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0010817 regulation of hormone levels; GO:0090066 regulation of anatomical structure size; GO:0016101 diterpenoid metabolic process; GO:0006721 terpenoid metabolic process; GO:0006082 organic acid metabolic process; GO:0003013 circulatory system process; GO:0009056 catabolic process; GO:0043436 oxoacid metabolic process; GO:0065007 biological regulation; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0004180 carboxypeptidase activity; GO:0008233 peptidase activity; GO:0008238 exopeptidase activity; GO:0017171 serine hydrolase activity; GO:0003824 catalytic activity; GO:0008236 serine-type peptidase activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0004185 serine-type carboxypeptidase activity; GO:0016787 hydrolase activity; GO:0070008 serine-type exopeptidase activity; ","K09646",null,null,"IPR029058; ","Alpha/Beta hydrolase fold; \r"]
["Q9HBL0","Tensin-1 OS=Homo sapiens OX=9606 GN=TNS1","TNS1",185.7,210.89,18.7,26,36,24,1.102,1.034,1.086,0.956,0.939,0.933,0.878,0.00322,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0016477 cell migration; GO:0007044 cell-substrate junction assembly; GO:0016043 cellular component organization; GO:0034329 cell junction assembly; GO:0051674 localization of cell; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0048870 cell motility; GO:0034330 cell junction organization; GO:0022607 cellular component assembly; GO:0001667 ameboidal-type cell migration; GO:0010761 fibroblast migration; GO:0006928 movement of cell or subcellular component; GO:0040011 locomotion; GO:0051179 localization; GO:0009987 cellular process; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0070161 anchoring junction; GO:0044424 intracellular part; GO:0005623 cell; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0005856 cytoskeleton; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:0009986 cell surface; GO:0030055 cell-substrate junction; GO:0005924 cell-substrate adherens junction; ","GO:0003779 actin binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005515 protein binding; GO:0008092 cytoskeletal protein binding; GO:0005488 binding; GO:0003676 nucleic acid binding; ","K18080",null,null,"IPR013625; IPR029023; IPR033929; IPR003595; IPR006020; IPR029021; IPR000980; IPR011993; IPR014020; IPR000008; ","\"Tensin/EPS8 phosphotyrosine-binding domain; Tensin phosphatase, lipid phosphatase domain; Tensin, phosphotyrosine-binding domain; Protein-tyrosine phosphatase, catalytic; PTB/PI domain; Protein-tyrosine phosphatase-like; SH2 domain; PH domain-like; Tensin phosphatase, C2 domain; C2 domain; \"\r"]
["Q9HBL7","Plasminogen receptor (KT) OS=Homo sapiens OX=9606 GN=PLGRKT","PLGRKT",17.201,5.8123,8.8,1,1,1,0.869,0.913,0.873,1.13,1.113,1.096,1.258,0.000221,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0032270 positive regulation of cellular protein metabolic process; GO:1903319 positive regulation of protein maturation; GO:0060255 regulation of macromolecule metabolic process; GO:0050896 response to stimulus; GO:0009605 response to external stimulus; GO:0045862 positive regulation of proteolysis; GO:0009893 positive regulation of metabolic process; GO:0010628 positive regulation of gene expression; GO:0010468 regulation of gene expression; GO:0006950 response to stress; GO:0080090 regulation of primary metabolic process; GO:0048522 positive regulation of cellular process; GO:0030162 regulation of proteolysis; GO:0031323 regulation of cellular metabolic process; GO:0006935 chemotaxis; GO:0048518 positive regulation of biological process; GO:0042221 response to chemical; GO:0051247 positive regulation of protein metabolic process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0010954 positive regulation of protein processing; GO:0051246 regulation of protein metabolic process; GO:0006954 inflammatory response; GO:0031325 positive regulation of cellular metabolic process; GO:0070613 regulation of protein processing; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0042330 taxis; GO:0006952 defense response; GO:0040011 locomotion; GO:1903317 regulation of protein maturation; GO:0010755 regulation of plasminogen activation; GO:0010756 positive regulation of plasminogen activation; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0031226 intrinsic component of plasma membrane; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; "]
["Q9HC35","Echinoderm microtubule-associated protein-like 4 OS=Homo sapiens OX=9606 GN=EML4","EML4",108.91,68.472,10.9,9,13,9,1.012,0.966,0.899,0.96,1.027,1.048,1.055,0.282,"plasma membrane\r","GO:0016043 cellular component organization; GO:0000278 mitotic cell cycle; GO:0006996 organelle organization; GO:0007067 mitotic nuclear division; GO:0048285 organelle fission; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0000280 nuclear division; GO:0022402 cell cycle process; GO:0007017 microtubule-based process; GO:0009987 cellular process; GO:1903047 mitotic cell cycle process; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0099513 polymeric cytoskeletal fiber; GO:0005874 microtubule; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0099081 supramolecular polymer; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0005856 cytoskeleton; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; ","GO:0015631 tubulin binding; GO:0005515 protein binding; GO:0008092 cytoskeletal protein binding; GO:0008017 microtubule binding; GO:0005488 binding; ","K15420","EML4; echinoderm microtubule-associated protein-like 4","hsa05223 Non-small cell lung cancer - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); ","IPR005108; IPR017986; IPR015943; IPR011047; ","HELP; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain; Quinoprotein alcohol dehydrogenase-like superfamily; \r"]
["Q9HCB6","Spondin-1 OS=Homo sapiens OX=9606 GN=SPON1","SPON1",90.973,32.827,5.1,3,3,3,0.929,1.138,1.084,0.903,0.922,1.036,0.908,0.273,"extracellular\r","GO:0043413 macromolecule glycosylation; GO:0036065 fucosylation; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0022610 biological adhesion; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:1901135 carbohydrate derivative metabolic process; GO:0007155 cell adhesion; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0070085 glycosylation; GO:0006486 protein glycosylation; GO:0009101 glycoprotein biosynthetic process; GO:0044763 single-organism cellular process; GO:0009100 glycoprotein metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0006493 protein O-linked glycosylation; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:0036066 protein O-linked fucosylation; ","GO:0005788 endoplasmic reticulum lumen; GO:0043229 intracellular organelle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0031012 extracellular matrix; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044432 endoplasmic reticulum part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005578 proteinaceous extracellular matrix; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0005488 binding; GO:0043167 ion binding; ",{"$nulls":3},"IPR002861; IPR009465; ","\"Reeler domain; Spondin, N-terminal; \"\r"]
["Q9HCL2","Glycerol-3-phosphate acyltransferase 1, mitochondrial OS=Homo sapiens OX=9606 GN=GPAM","GPAM",93.794,11.373,2.9,2,2,2,1.091,1.041,1.066,0.931,0.969,0.918,0.881,0.0039,"cytoplasm\r","GO:0002694 regulation of leukocyte activation; GO:0010941 regulation of cell death; GO:0065008 regulation of biological quality; GO:0032944 regulation of mononuclear cell proliferation; GO:0098542 defense response to other organism; GO:0044255 cellular lipid metabolic process; GO:0009749 response to glucose; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0019432 triglyceride biosynthetic process; GO:0045927 positive regulation of growth; GO:0009607 response to biotic stimulus; GO:0008610 lipid biosynthetic process; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0032946 positive regulation of mononuclear cell proliferation; GO:0051240 positive regulation of multicellular organismal process; GO:0016024 CDP-diacylglycerol biosynthetic process; GO:0032879 regulation of localization; GO:0006639 acylglycerol metabolic process; GO:0009306 protein secretion; GO:0032787 monocarboxylic acid metabolic process; GO:0009743 response to carbohydrate; GO:0044419 interspecies interaction between organisms; GO:0008104 protein localization; GO:0055088 lipid homeostasis; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0006790 sulfur compound metabolic process; GO:0040014 regulation of multicellular organism growth; GO:0044281 small molecule metabolic process; GO:0070229 negative regulation of lymphocyte apoptotic process; GO:0044763 single-organism cellular process; GO:0046006 regulation of activated T cell proliferation; GO:0050707 regulation of cytokine secretion; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0050670 regulation of lymphocyte proliferation; GO:0006732 coenzyme metabolic process; GO:0046473 phosphatidic acid metabolic process; GO:0032501 multicellular organismal process; GO:0070233 negative regulation of T cell apoptotic process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0090407 organophosphate biosynthetic process; GO:0044710 single-organism metabolic process; GO:0034284 response to monosaccharide; GO:0002682 regulation of immune system process; GO:0051223 regulation of protein transport; GO:0051094 positive regulation of developmental process; GO:0060548 negative regulation of cell death; GO:0043436 oxoacid metabolic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0042127 regulation of cell proliferation; GO:1901700 response to oxygen-containing compound; GO:0043067 regulation of programmed cell death; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0032844 regulation of homeostatic process; GO:0051239 regulation of multicellular organismal process; GO:0050867 positive regulation of cell activation; GO:1902578 single-organism localization; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:0070235 regulation of activation-induced cell death of T cells; GO:0032880 regulation of protein localization; GO:0070232 regulation of T cell apoptotic process; GO:0048878 chemical homeostasis; GO:0050663 cytokine secretion; GO:0006638 neutral lipid metabolic process; GO:0006950 response to stress; GO:0045785 positive regulation of cell adhesion; GO:0044711 single-organism biosynthetic process; GO:0035383 thioester metabolic process; GO:0002376 immune system process; GO:0071702 organic substance transport; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1903039 positive regulation of leukocyte cell-cell adhesion; GO:1901576 organic substance biosynthetic process; GO:0032623 interleukin-2 production; GO:0030155 regulation of cell adhesion; GO:0045184 establishment of protein localization; GO:0002696 positive regulation of leukocyte activation; GO:0006641 triglyceride metabolic process; GO:0006793 phosphorus metabolic process; GO:0001816 cytokine production; GO:0050870 positive regulation of T cell activation; GO:0019637 organophosphate metabolic process; GO:0006644 phospholipid metabolic process; GO:0040018 positive regulation of multicellular organism growth; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:2000107 negative regulation of leukocyte apoptotic process; GO:0008284 positive regulation of cell proliferation; GO:0050863 regulation of T cell activation; GO:0046486 glycerolipid metabolic process; GO:0009746 response to hexose; GO:0006654 phosphatidic acid biosynthetic process; GO:0008654 phospholipid biosynthetic process; GO:0044699 single-organism process; GO:0051046 regulation of secretion; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0051249 regulation of lymphocyte activation; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0055091 phospholipid homeostasis; GO:0050671 positive regulation of lymphocyte proliferation; GO:0046460 neutral lipid biosynthetic process; GO:0006650 glycerophospholipid metabolic process; GO:0070663 regulation of leukocyte proliferation; GO:0046341 CDP-diacylglycerol metabolic process; GO:0033036 macromolecule localization; GO:0006629 lipid metabolic process; GO:0048639 positive regulation of developmental growth; GO:0050801 ion homeostasis; GO:0048522 positive regulation of cellular process; GO:0055081 anion homeostasis; GO:0051251 positive regulation of lymphocyte activation; GO:1903530 regulation of secretion by cell; GO:0051186 cofactor metabolic process; GO:0002683 negative regulation of immune system process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0050865 regulation of cell activation; GO:0051607 defense response to virus; GO:0070970 interleukin-2 secretion; GO:0032940 secretion by cell; GO:0046474 glycerophospholipid biosynthetic process; GO:0006952 defense response; GO:0006082 organic acid metabolic process; GO:0009615 response to virus; GO:0070228 regulation of lymphocyte apoptotic process; GO:0040008 regulation of growth; GO:0043069 negative regulation of programmed cell death; GO:0042102 positive regulation of T cell proliferation; GO:0002252 immune effector process; GO:0046463 acylglycerol biosynthetic process; GO:0043207 response to external biotic stimulus; GO:0048638 regulation of developmental growth; GO:0070236 negative regulation of activation-induced cell death of T cells; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0070201 regulation of establishment of protein localization; GO:0071704 organic substance metabolic process; GO:0042104 positive regulation of activated T cell proliferation; GO:0042592 homeostatic process; GO:0043066 negative regulation of apoptotic process; GO:0016032 viral process; GO:0050708 regulation of protein secretion; GO:0009987 cellular process; GO:0022409 positive regulation of cell-cell adhesion; GO:0051049 regulation of transport; GO:0055089 fatty acid homeostasis; GO:0042129 regulation of T cell proliferation; GO:0032845 negative regulation of homeostatic process; GO:0006631 fatty acid metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0006637 acyl-CoA metabolic process; GO:0022407 regulation of cell-cell adhesion; GO:0045017 glycerolipid biosynthetic process; GO:2000106 regulation of leukocyte apoptotic process; GO:0070665 positive regulation of leukocyte proliferation; GO:0002684 positive regulation of immune system process; GO:0019752 carboxylic acid metabolic process; GO:0001817 regulation of cytokine production; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0019867 outer membrane; GO:0044429 mitochondrial part; GO:0098588 bounding membrane of organelle; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0005741 mitochondrial outer membrane; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005740 mitochondrial envelope; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0031975 envelope; GO:0098805 whole membrane; GO:0019866 organelle inner membrane; GO:0031968 organelle outer membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0004366 glycerol-3-phosphate O-acyltransferase activity; GO:0016746 transferase activity, transferring acyl groups; GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups; GO:0003824 catalytic activity; GO:0016740 transferase activity; GO:0008374 O-acyltransferase activity; ","K00629","GPAT1_2; glycerol-3-phosphate O-acyltransferase 1/2 [EC:2.3.1.15]","hsa00564 Glycerophospholipid metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00561 Glycerolipid metabolism - Homo sapiens (human); ","IPR002123; ","Phospholipid/glycerol acyltransferase; \r"]
["Q9HCN4","GPN-loop GTPase 1 OS=Homo sapiens OX=9606 GN=GPN1","GPN1",41.74,1.9032,2.9,1,1,1,0.997,1.01,1.139,0.868,0.985,1.009,0.91,0.207,"mitochondria\r","GO:0046907 intracellular transport; GO:0072594 establishment of protein localization to organelle; GO:0017038 protein import; GO:1902593 single-organism nuclear import; GO:1990022 RNA polymerase III complex localization to nucleus; GO:0044699 single-organism process; GO:0051169 nuclear transport; GO:0044376 RNA polymerase II complex import to nucleus; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0051649 establishment of localization in cell; GO:1902578 single-organism localization; GO:0034629 cellular protein complex localization; GO:0006886 intracellular protein transport; GO:0044744 protein targeting to nucleus; GO:1902580 single-organism cellular localization; GO:0033365 protein localization to organelle; GO:0006606 protein import into nucleus; GO:0042886 amide transport; GO:0034613 cellular protein localization; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0044765 single-organism transport; GO:0071702 organic substance transport; GO:1902582 single-organism intracellular transport; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:0070727 cellular macromolecule localization; GO:0051170 nuclear import; GO:0006913 nucleocytoplasmic transport; GO:0051179 localization; GO:0015833 peptide transport; GO:0034504 protein localization to nucleus; GO:0071705 nitrogen compound transport; GO:0031503 protein complex localization; ","GO:0043229 intracellular organelle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0003924 GTPase activity; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019001 guanyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0036094 small molecule binding; ","K06883",null,null,"IPR003593; IPR027417; ","AAA+ ATPase domain; P-loop containing nucleoside triphosphate hydrolase; \r"]
["Q9HCY8","Protein S100-A14 OS=Homo sapiens OX=9606 GN=S100A14","S100A14",11.662,76.846,72.1,6,16,6,0.798,0.76,0.738,1.22,1.248,1.211,1.602,4.15e-05,"cyto_nucl\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0030335 positive regulation of cell migration; GO:0040017 positive regulation of locomotion; GO:0098542 defense response to other organism; GO:0044699 single-organism process; GO:0031347 regulation of defense response; GO:0009607 response to biotic stimulus; GO:0009605 response to external stimulus; GO:0007165 signal transduction; GO:0090026 positive regulation of monocyte chemotaxis; GO:0007154 cell communication; GO:0045088 regulation of innate immune response; GO:0032879 regulation of localization; GO:0006915 apoptotic process; GO:0032103 positive regulation of response to external stimulus; GO:0055065 metal ion homeostasis; GO:0002221 pattern recognition receptor signaling pathway; GO:0050921 positive regulation of chemotaxis; GO:0051716 cellular response to stimulus; GO:0050801 ion homeostasis; GO:0002758 innate immune response-activating signal transduction; GO:0055074 calcium ion homeostasis; GO:0002237 response to molecule of bacterial origin; GO:0044763 single-organism cellular process; GO:0098771 inorganic ion homeostasis; GO:0048522 positive regulation of cellular process; GO:0002688 regulation of leukocyte chemotaxis; GO:0051272 positive regulation of cellular component movement; GO:0023052 signaling; GO:0002764 immune response-regulating signaling pathway; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0002224 toll-like receptor signaling pathway; GO:0048583 regulation of response to stimulus; GO:0071624 positive regulation of granulocyte chemotaxis; GO:0002682 regulation of immune system process; GO:0006952 defense response; GO:0071677 positive regulation of mononuclear cell migration; GO:0002685 regulation of leukocyte migration; GO:0072507 divalent inorganic cation homeostasis; GO:0071675 regulation of mononuclear cell migration; GO:0002687 positive regulation of leukocyte migration; GO:0050794 regulation of cellular process; GO:0071622 regulation of granulocyte chemotaxis; GO:0002218 activation of innate immune response; GO:0090025 regulation of monocyte chemotaxis; GO:1901700 response to oxygen-containing compound; GO:0080134 regulation of response to stress; GO:2000147 positive regulation of cell motility; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0033993 response to lipid; GO:0042592 homeostatic process; GO:0031349 positive regulation of defense response; GO:0002690 positive regulation of leukocyte chemotaxis; GO:0055080 cation homeostasis; GO:2000145 regulation of cell motility; GO:0002757 immune response-activating signal transduction; GO:0050778 positive regulation of immune response; GO:0009987 cellular process; GO:0009617 response to bacterium; GO:0048878 chemical homeostasis; GO:0002253 activation of immune response; GO:0045089 positive regulation of innate immune response; GO:0006950 response to stress; GO:0042742 defense response to bacterium; GO:0051270 regulation of cellular component movement; GO:0032496 response to lipopolysaccharide; GO:0002376 immune system process; GO:0030334 regulation of cell migration; GO:0032101 regulation of response to external stimulus; GO:0010033 response to organic substance; GO:0050920 regulation of chemotaxis; GO:0048518 positive regulation of biological process; GO:0034142 toll-like receptor 4 signaling pathway; GO:0008219 cell death; GO:0002684 positive regulation of immune system process; GO:0012501 programmed cell death; GO:0040012 regulation of locomotion; GO:0048584 positive regulation of response to stimulus; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0030054 cell junction; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043230 extracellular organelle; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005102 receptor binding; GO:0005488 binding; GO:0043167 ion binding; GO:0042379 chemokine receptor binding; GO:0005126 cytokine receptor binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0001664 G-protein coupled receptor binding; GO:0005515 protein binding; GO:0005509 calcium ion binding; ",{"$nulls":3},"IPR011992; IPR013787; ","\"EF-hand domain pair; S100/CaBP-9k-type, calcium binding, subdomain; \"\r"]
["Q9HD20","Manganese-transporting ATPase 13A1 OS=Homo sapiens OX=9606 GN=ATP13A1","ATP13A1",132.95,32.851,10.9,10,11,10,0.973,0.95,0.861,1.066,0.948,1.202,1.155,0.145,"plasma membrane\r","GO:0071421 manganese ion transmembrane transport; GO:0065008 regulation of biological quality; GO:0072503 cellular divalent inorganic cation homeostasis; GO:0072511 divalent inorganic cation transport; GO:0034220 ion transmembrane transport; GO:0090662 ATP hydrolysis coupled transmembrane transport; GO:0030001 metal ion transport; GO:0030003 cellular cation homeostasis; GO:0044699 single-organism process; GO:0006828 manganese ion transport; GO:0055082 cellular chemical homeostasis; GO:0051234 establishment of localization; GO:0042592 homeostatic process; GO:0000041 transition metal ion transport; GO:0055080 cation homeostasis; GO:0006812 cation transport; GO:0006816 calcium ion transport; GO:0055065 metal ion homeostasis; GO:0099132 ATP hydrolysis coupled cation transmembrane transport; GO:0099131 ATP hydrolysis coupled ion transmembrane transport; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0070588 calcium ion transmembrane transport; GO:0098655 cation transmembrane transport; GO:0050801 ion homeostasis; GO:0098660 inorganic ion transmembrane transport; GO:0055074 calcium ion homeostasis; GO:0098771 inorganic ion homeostasis; GO:0044763 single-organism cellular process; GO:0019725 cellular homeostasis; GO:0006874 cellular calcium ion homeostasis; GO:0006810 transport; GO:0055085 transmembrane transport; GO:0006873 cellular ion homeostasis; GO:0006811 ion transport; GO:0006875 cellular metal ion homeostasis; GO:0051179 localization; GO:0072507 divalent inorganic cation homeostasis; GO:0098662 inorganic cation transmembrane transport; GO:0065007 biological regulation; GO:0070838 divalent metal ion transport; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0031226 intrinsic component of plasma membrane; GO:0005783 endoplasmic reticulum; GO:0071944 cell periphery; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0044432 endoplasmic reticulum part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; ","GO:0042625 ATPase coupled ion transmembrane transporter activity; GO:1901265 nucleoside phosphate binding; GO:0015399 primary active transmembrane transporter activity; GO:0015410 manganese-transporting ATPase activity; GO:0022892 substrate-specific transporter activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0016887 ATPase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0046873 metal ion transmembrane transporter activity; GO:0019829 cation-transporting ATPase activity; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0043492 ATPase activity, coupled to movement of substances; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0022890 inorganic cation transmembrane transporter activity; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005215 transporter activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0022804 active transmembrane transporter activity; GO:0005384 manganese ion transmembrane transporter activity; GO:0005524 ATP binding; GO:0015075 ion transmembrane transporter activity; GO:0022853 active ion transmembrane transporter activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0046915 transition metal ion transmembrane transporter activity; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0015662 ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism; GO:0072509 divalent inorganic cation transmembrane transporter activity; GO:0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity; GO:0097367 carbohydrate derivative binding; GO:0005388 calcium-transporting ATPase activity; GO:0042626 ATPase activity, coupled to transmembrane movement of substances; GO:0042623 ATPase activity, coupled; GO:0046872 metal ion binding; GO:0015085 calcium ion transmembrane transporter activity; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0008324 cation transmembrane transporter activity; GO:0022857 transmembrane transporter activity; GO:0036094 small molecule binding; ","K14950",null,null,"IPR008250; IPR023299; IPR023214; ","\"P-type ATPase, A  domain; P-type ATPase, cytoplasmic domain N; HAD-like domain; \"\r"]
["Q9NNW7","Thioredoxin reductase 2, mitochondrial OS=Homo sapiens OX=9606 GN=TXNRD2","TXNRD2",56.506,5.5907,2.7,1,1,1,1.056,1.201,1.115,0.879,0.858,0.916,0.787,0.00468,"mitochondria\r","GO:0050794 regulation of cellular process; GO:0065008 regulation of biological quality; GO:0006950 response to stress; GO:0055114 oxidation-reduction process; GO:0009636 response to toxic substance; GO:0000302 response to reactive oxygen species; GO:0045454 cell redox homeostasis; GO:1901700 response to oxygen-containing compound; GO:0044763 single-organism cellular process; GO:0019725 cellular homeostasis; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0042592 homeostatic process; GO:0008152 metabolic process; GO:1990748 cellular detoxification; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0044710 single-organism metabolic process; GO:0006979 response to oxidative stress; GO:0000305 response to oxygen radical; GO:0098869 cellular oxidant detoxification; GO:0010035 response to inorganic substance; GO:0098754 detoxification; GO:0009987 cellular process; GO:0065007 biological regulation; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:1901265 nucleoside phosphate binding; GO:0050660 flavin adenine dinucleotide binding; GO:0004791 thioredoxin-disulfide reductase activity; GO:0043167 ion binding; GO:0016209 antioxidant activity; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor; GO:0048037 cofactor binding; GO:0016491 oxidoreductase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0015036 disulfide oxidoreductase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016667 oxidoreductase activity, acting on a sulfur group of donors; GO:0043168 anion binding; GO:0050662 coenzyme binding; GO:0036094 small molecule binding; ","K00384",null,null,"IPR016156; IPR004099; IPR023753; ","\"FAD/NAD-linked reductase, dimerisation domain; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; FAD/NAD(P)-binding domain; \"\r"]
["Q9NP58","ATP-binding cassette sub-family B member 6, mitochondrial OS=Homo sapiens OX=9606 GN=ABCB6","ABCB6",93.884,38.968,6.4,3,4,3,0.962,1.063,1.076,0.97,0.966,0.975,0.939,0.224,"plasma membrane\r","GO:0051188 cofactor biosynthetic process; GO:0065008 regulation of biological quality; GO:0007420 brain development; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0015886 heme transport; GO:0055065 metal ion homeostasis; GO:0060322 head development; GO:0044765 single-organism transport; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0018130 heterocycle biosynthetic process; GO:0043588 skin development; GO:0050801 ion homeostasis; GO:0051181 cofactor transport; GO:0044763 single-organism cellular process; GO:0098771 inorganic ion homeostasis; GO:1901360 organic cyclic compound metabolic process; GO:0019725 cellular homeostasis; GO:0032501 multicellular organismal process; GO:0051186 cofactor metabolic process; GO:0046916 cellular transition metal ion homeostasis; GO:0006810 transport; GO:0048513 animal organ development; GO:0007417 central nervous system development; GO:0033013 tetrapyrrole metabolic process; GO:0033014 tetrapyrrole biosynthetic process; GO:0048856 anatomical structure development; GO:1901362 organic cyclic compound biosynthetic process; GO:0006879 cellular iron ion homeostasis; GO:0044707 single-multicellular organism process; GO:0055076 transition metal ion homeostasis; GO:0006725 cellular aromatic compound metabolic process; GO:0030003 cellular cation homeostasis; GO:0055072 iron ion homeostasis; GO:1901566 organonitrogen compound biosynthetic process; GO:0055082 cellular chemical homeostasis; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0006778 porphyrin-containing compound metabolic process; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0055080 cation homeostasis; GO:0019438 aromatic compound biosynthetic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0048731 system development; GO:0006779 porphyrin-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0055085 transmembrane transport; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006873 cellular ion homeostasis; GO:0044767 single-organism developmental process; GO:0006875 cellular metal ion homeostasis; GO:1901678 iron coordination entity transport; GO:0051179 localization; GO:0071705 nitrogen compound transport; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0019867 outer membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0031306 intrinsic component of mitochondrial outer membrane; GO:0032991 macromolecular complex; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0031301 integral component of organelle membrane; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043190 ATP-binding cassette (ABC) transporter complex; GO:0043233 organelle lumen; GO:0010008 endosome membrane; GO:0098797 plasma membrane protein complex; GO:0031967 organelle envelope; GO:0044440 endosomal part; GO:0031981 nuclear lumen; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0031975 envelope; GO:0043234 protein complex; GO:0031966 mitochondrial membrane; GO:0043230 extracellular organelle; GO:0031300 intrinsic component of organelle membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0098796 membrane protein complex; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0098533 ATPase dependent transmembrane transport complex; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0031307 integral component of mitochondrial outer membrane; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0031968 organelle outer membrane; GO:0005768 endosome; GO:1990351 transporter complex; GO:0043229 intracellular organelle; GO:0098573 intrinsic component of mitochondrial membrane; GO:0097708 intracellular vesicle; GO:0044429 mitochondrial part; GO:0098588 bounding membrane of organelle; GO:0005741 mitochondrial outer membrane; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:1902495 transmembrane transporter complex; GO:0016021 integral component of membrane; GO:0043226 organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0044432 endoplasmic reticulum part; GO:1904949 ATPase complex; GO:0032592 integral component of mitochondrial membrane; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0015232 heme transporter activity; GO:0015562 efflux transmembrane transporter activity; GO:1901265 nucleoside phosphate binding; GO:0015399 primary active transmembrane transporter activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0051184 cofactor transporter activity; GO:0016887 ATPase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0020037 heme binding; GO:0016462 pyrophosphatase activity; GO:0015439 heme-transporting ATPase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0043492 ATPase activity, coupled to movement of substances; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0046906 tetrapyrrole binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005215 transporter activity; GO:0022804 active transmembrane transporter activity; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity; GO:0042626 ATPase activity, coupled to transmembrane movement of substances; GO:0042623 ATPase activity, coupled; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; GO:0022857 transmembrane transporter activity; ","K05661","ABCB6; ATP-binding cassette, subfamily B (MDR/TAP), member 6","hsa02010 ABC transporters - Homo sapiens (human); ","IPR003593; IPR032410; IPR003439; IPR011527; IPR027417; ","\"AAA+ ATPase domain; Mitochondrial ABC-transporter, N-terminal five TM domain; ABC transporter-like; ABC transporter type 1, transmembrane domain; P-loop containing nucleoside triphosphate hydrolase; \"\r"]
["Q9NP72","Ras-related protein Rab-18 OS=Homo sapiens OX=9606 GN=RAB18","RAB18",22.977,47.307,36.9,6,10,6,0.898,0.881,0.865,1.096,1.088,1.144,1.259,0.000264,"cytoplasm\r","GO:0044700 single organism signaling; GO:0010256 endomembrane system organization; GO:0045321 leukocyte activation; GO:0007420 brain development; GO:0044699 single-organism process; GO:0051169 nuclear transport; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0034389 lipid particle organization; GO:0060322 head development; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0002274 myeloid leukocyte activation; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0007264 small GTPase mediated signal transduction; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0002444 myeloid leukocyte mediated immunity; GO:1902582 single-organism intracellular transport; GO:0006810 transport; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0032940 secretion by cell; GO:0007417 central nervous system development; GO:0006913 nucleocytoplasmic transport; GO:0043299 leukocyte degranulation; GO:0048856 anatomical structure development; GO:0007029 endoplasmic reticulum organization; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:1902593 single-organism nuclear import; GO:0071786 endoplasmic reticulum tubular network organization; GO:0050896 response to stimulus; GO:0001654 eye development; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:1902580 single-organism cellular localization; GO:0007275 multicellular organism development; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0035556 intracellular signal transduction; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0071702 organic substance transport; GO:0002376 immune system process; GO:0043312 neutrophil degranulation; GO:0002263 cell activation involved in immune response; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0051170 nuclear import; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0061024 membrane organization; GO:0001775 cell activation; GO:0007423 sensory organ development; GO:0006955 immune response; GO:0051179 localization; GO:0006887 exocytosis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0098827 endoplasmic reticulum subcompartment; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0071782 endoplasmic reticulum tubular network; GO:0043226 organelle; GO:0030667 secretory granule membrane; GO:0044432 endoplasmic reticulum part; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0031984 organelle subcompartment; ","GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016462 pyrophosphatase activity; GO:0019003 GDP binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0003924 GTPase activity; GO:0032550 purine ribonucleoside binding; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; ","K07910",null,null,"IPR005225; IPR027417; ","Small GTP-binding protein domain; P-loop containing nucleoside triphosphate hydrolase; \r"]
["Q9NP74","Palmdelphin OS=Homo sapiens OX=9606 GN=PALMD","PALMD",62.757,16.994,12,6,7,5,1.035,1.032,1.027,0.969,0.939,1.054,0.957,0.324,"nucleus\r","GO:0050794 regulation of cellular process; GO:0065008 regulation of biological quality; GO:0050789 regulation of biological process; GO:0008360 regulation of cell shape; GO:0022603 regulation of anatomical structure morphogenesis; GO:0051128 regulation of cellular component organization; GO:0050793 regulation of developmental process; GO:0022604 regulation of cell morphogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0030425 dendrite; GO:0042995 cell projection; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0044463 cell projection part; GO:0005623 cell; GO:0043197 dendritic spine; GO:0045202 synapse; GO:0036477 somatodendritic compartment; GO:0098794 postsynapse; GO:0044309 neuron spine; GO:0044464 cell part; GO:0005622 intracellular; GO:0043005 neuron projection; GO:0097458 neuron part; GO:0044456 synapse part; ",null,"K16519"]
["Q9NPF4","Probable tRNA N6-adenosine threonylcarbamoyltransferase OS=Homo sapiens OX=9606 GN=OSGEP","OSGEP",36.426,3.929,6.9,2,2,2,1.094,1.01,0.99,1.033,0.909,0.98,0.944,0.297,"cyto_nucl\r","GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0006725 cellular aromatic compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:0009451 RNA modification; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0016070 RNA metabolic process; GO:0008152 metabolic process; GO:0006399 tRNA metabolic process; GO:0090304 nucleic acid metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0070525 tRNA threonylcarbamoyladenosine metabolic process; GO:0008033 tRNA processing; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0034641 cellular nitrogen compound metabolic process; GO:0002949 tRNA threonylcarbamoyladenosine modification; GO:0043170 macromolecule metabolic process; GO:0006400 tRNA modification; GO:0043412 macromolecule modification; GO:0009987 cellular process; GO:0034660 ncRNA metabolic process; ","GO:0016020 membrane; GO:0043229 intracellular organelle; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0005886 plasma membrane; GO:0000408 EKC/KEOPS complex; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0043234 protein complex; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0016746 transferase activity, transferring acyl groups; GO:0061711 N(6)-L-threonylcarbamoyladenine synthase; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0016740 transferase activity; GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups; ","K01409",null,null,"IPR000905; ","Gcp-like domain; \r"]
["Q9NPH2","Inositol-3-phosphate synthase 1 OS=Homo sapiens OX=9606 GN=ISYNA1","ISYNA1",61.067,19.712,7.3,3,3,3,1.23,1.248,1.258,0.857,0.696,0.755,0.618,0.0154,"nucleus\r","GO:0016051 carbohydrate biosynthetic process; GO:1901615 organic hydroxy compound metabolic process; GO:0006066 alcohol metabolic process; GO:0006020 inositol metabolic process; GO:0008654 phospholipid biosynthetic process; GO:0006021 inositol biosynthetic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0008610 lipid biosynthetic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0044262 cellular carbohydrate metabolic process; GO:0034637 cellular carbohydrate biosynthetic process; GO:0009987 cellular process; GO:0006629 lipid metabolic process; GO:0044711 single-organism biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0046165 alcohol biosynthetic process; GO:1901617 organic hydroxy compound biosynthetic process; GO:0005975 carbohydrate metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0019751 polyol metabolic process; GO:0044249 cellular biosynthetic process; GO:0090407 organophosphate biosynthetic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0044283 small molecule biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0043647 inositol phosphate metabolic process; GO:0046173 polyol biosynthetic process; GO:0006644 phospholipid metabolic process; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0044444 cytoplasmic part; ","GO:0016872 intramolecular lyase activity; GO:0005515 protein binding; GO:0004512 inositol-3-phosphate synthase activity; GO:0016853 isomerase activity; GO:0003824 catalytic activity; GO:0005488 binding; ","K01858","INO1; myo-inositol-1-phosphate synthase [EC:5.5.1.4]","hsa00562 Inositol phosphate metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR013021; IPR016040; ","\"Myo-inositol-1-phosphate synthase, GAPDH-like; NAD(P)-binding domain; \"\r"]
["Q9NQ38","Serine protease inhibitor Kazal-type 5 OS=Homo sapiens OX=9606 GN=SPINK5","SPINK5",120.71,4.5281,2.8,3,3,3,1.07,1.081,0.897,1.053,0.88,1.037,0.974,0.775,"extracellular\r","GO:0002694 regulation of leukocyte activation; GO:0021700 developmental maturation; GO:0031424 keratinization; GO:0002698 negative regulation of immune effector process; GO:0031347 regulation of defense response; GO:0035315 hair cell differentiation; GO:0010466 negative regulation of peptidase activity; GO:0009913 epidermal cell differentiation; GO:0032102 negative regulation of response to external stimulus; GO:0008544 epidermis development; GO:0052548 regulation of endopeptidase activity; GO:0007399 nervous system development; GO:0043588 skin development; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0070268 cornification; GO:0044763 single-organism cellular process; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:1901343 negative regulation of vasculature development; GO:0032501 multicellular organismal process; GO:0002701 negative regulation of production of molecular mediator of immune response; GO:0050776 regulation of immune response; GO:0098773 skin epidermis development; GO:0048513 animal organ development; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0048583 regulation of response to stimulus; GO:0002784 regulation of antimicrobial peptide production; GO:0045765 regulation of angiogenesis; GO:0002682 regulation of immune system process; GO:0001942 hair follicle development; GO:0042640 anagen; GO:0030855 epithelial cell differentiation; GO:0050794 regulation of cellular process; GO:0002786 regulation of antibacterial peptide production; GO:0044707 single-multicellular organism process; GO:0010951 negative regulation of endopeptidase activity; GO:0045580 regulation of T cell differentiation; GO:0042303 molting cycle; GO:0002920 regulation of humoral immune response; GO:0080134 regulation of response to stress; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0051239 regulation of multicellular organismal process; GO:1903706 regulation of hemopoiesis; GO:0043062 extracellular structure organization; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:0048820 hair follicle maturation; GO:0007275 multicellular organism development; GO:0045861 negative regulation of proteolysis; GO:0048731 system development; GO:0043900 regulation of multi-organism process; GO:0044848 biological phase; GO:0032101 regulation of response to external stimulus; GO:1902572 negative regulation of serine-type peptidase activity; GO:0022405 hair cycle process; GO:0030162 regulation of proteolysis; GO:0042633 hair cycle; GO:0009892 negative regulation of metabolic process; GO:0030155 regulation of cell adhesion; GO:0030182 neuron differentiation; GO:1900004 negative regulation of serine-type endopeptidase activity; GO:0012501 programmed cell death; GO:0050793 regulation of developmental process; GO:0050863 regulation of T cell activation; GO:0044851 hair cycle phase; GO:0051093 negative regulation of developmental process; GO:1900424 regulation of defense response to bacterium; GO:0048869 cellular developmental process; GO:0002759 regulation of antimicrobial humoral response; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0051241 negative regulation of multicellular organismal process; GO:0051249 regulation of lymphocyte activation; GO:0002787 negative regulation of antibacterial peptide production; GO:0022404 molting cycle process; GO:0050777 negative regulation of immune response; GO:0030198 extracellular matrix organization; GO:0008348 negative regulation of antimicrobial humoral response; GO:0002697 regulation of immune effector process; GO:0032502 developmental process; GO:2000181 negative regulation of blood vessel morphogenesis; GO:0060429 epithelium development; GO:0002832 negative regulation of response to biotic stimulus; GO:0009888 tissue development; GO:0030216 keratinocyte differentiation; GO:0002700 regulation of production of molecular mediator of immune response; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002683 negative regulation of immune system process; GO:0050865 regulation of cell activation; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0016525 negative regulation of angiogenesis; GO:1902105 regulation of leukocyte differentiation; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0052547 regulation of peptidase activity; GO:0048856 anatomical structure development; GO:0071695 anatomical structure maturation; GO:2000026 regulation of multicellular organismal development; GO:0016043 cellular component organization; GO:0002831 regulation of response to biotic stimulus; GO:0060255 regulation of macromolecule metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0002921 negative regulation of humoral immune response; GO:0051346 negative regulation of hydrolase activity; GO:0030154 cell differentiation; GO:1900425 negative regulation of defense response to bacterium; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0031348 negative regulation of defense response; GO:0002785 negative regulation of antimicrobial peptide production; GO:1900003 regulation of serine-type endopeptidase activity; GO:1901342 regulation of vasculature development; GO:0048585 negative regulation of response to stimulus; GO:1902571 regulation of serine-type peptidase activity; GO:0022407 regulation of cell-cell adhesion; GO:0045619 regulation of lymphocyte differentiation; GO:0043901 negative regulation of multi-organism process; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0051248 negative regulation of protein metabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0005938 cell cortex; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0099568 cytoplasmic region; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0042599 lamellar body; GO:0005623 cell; GO:0044422 organelle part; GO:0097209 epidermal lamellar body; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044432 endoplasmic reticulum part; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0004867 serine-type endopeptidase inhibitor activity; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0030414 peptidase inhibitor activity; GO:0061134 peptidase regulator activity; GO:0005515 protein binding; GO:0061135 endopeptidase regulator activity; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0004866 endopeptidase inhibitor activity; ",{"$nulls":3},"IPR002350; ","Kazal domain; \r"]
["Q9NQ48","Leucine zipper transcription factor-like protein 1 OS=Homo sapiens OX=9606 GN=LZTFL1","LZTFL1",34.592,23.165,15.7,4,4,4,1.042,0.991,1.012,0.979,1.023,0.997,0.985,0.477,"cytoplasm\r","GO:1903565 negative regulation of protein localization to cilium; GO:1905476 negative regulation of protein localization to membrane; GO:1903828 negative regulation of cellular protein localization; GO:1903567 regulation of protein localization to ciliary membrane; GO:1904376 negative regulation of protein localization to cell periphery; GO:0048519 negative regulation of biological process; GO:1903568 negative regulation of protein localization to ciliary membrane; GO:0060341 regulation of cellular localization; GO:1905475 regulation of protein localization to membrane; GO:1904375 regulation of protein localization to cell periphery; GO:0050789 regulation of biological process; GO:1903564 regulation of protein localization to cilium; GO:0032879 regulation of localization; GO:0032880 regulation of protein localization; GO:1903827 regulation of cellular protein localization; GO:0065007 biological regulation; ","GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0042802 identical protein binding; GO:0005488 binding; GO:0032403 protein complex binding; GO:0044877 macromolecular complex binding; ","K19400"]
["Q9NQE9","Histidine triad nucleotide-binding protein 3 OS=Homo sapiens OX=9606 GN=HINT3","HINT3",20.361,28.085,23.6,3,3,3,1.067,1.137,1.037,0.848,1.006,0.922,0.857,0.0499,"extracellular\r",null,"GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0016787 hydrolase activity; GO:0000166 nucleotide binding; GO:1901265 nucleoside phosphate binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0036094 small molecule binding; ",{"$nulls":3},"IPR011146; ","HIT-like domain; \r"]
["Q9NQG6","Mitochondrial dynamics protein MID51 OS=Homo sapiens OX=9606 GN=MIEF1","MIEF1",51.293,1.9237,2.2,1,1,1,1.018,0.917,1.079,1.061,1.02,0.913,0.993,0.927,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0090316 positive regulation of intracellular protein transport; GO:1903533 regulation of protein targeting; GO:1903829 positive regulation of cellular protein localization; GO:0048285 organelle fission; GO:1905477 positive regulation of protein localization to membrane; GO:0010821 regulation of mitochondrion organization; GO:0070201 regulation of establishment of protein localization; GO:0060341 regulation of cellular localization; GO:0051130 positive regulation of cellular component organization; GO:1905475 regulation of protein localization to membrane; GO:0032879 regulation of localization; GO:0007005 mitochondrion organization; GO:0032880 regulation of protein localization; GO:0090140 regulation of mitochondrial fission; GO:0009987 cellular process; GO:0090314 positive regulation of protein targeting to membrane; GO:0033157 regulation of intracellular protein transport; GO:0032388 positive regulation of intracellular transport; GO:0051049 regulation of transport; GO:0033043 regulation of organelle organization; GO:0048522 positive regulation of cellular process; GO:0032386 regulation of intracellular transport; GO:0048518 positive regulation of biological process; GO:0000266 mitochondrial fission; GO:0010822 positive regulation of mitochondrion organization; GO:0051050 positive regulation of transport; GO:0090141 positive regulation of mitochondrial fission; GO:0050789 regulation of biological process; GO:1904951 positive regulation of establishment of protein localization; GO:0010638 positive regulation of organelle organization; GO:0006996 organelle organization; GO:0022603 regulation of anatomical structure morphogenesis; GO:0051223 regulation of protein transport; GO:0051128 regulation of cellular component organization; GO:0051094 positive regulation of developmental process; GO:0050793 regulation of developmental process; GO:1903827 regulation of cellular protein localization; GO:0090313 regulation of protein targeting to membrane; GO:0051222 positive regulation of protein transport; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0019867 outer membrane; GO:0044429 mitochondrial part; GO:0098588 bounding membrane of organelle; GO:0031090 organelle membrane; GO:0005741 mitochondrial outer membrane; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005740 mitochondrial envelope; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0031975 envelope; GO:0098805 whole membrane; GO:0031968 organelle outer membrane; GO:0043227 membrane-bounded organelle; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0042802 identical protein binding; GO:0019003 GDP binding; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043531 ADP binding; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019001 guanyl nucleotide binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; ",{"$nulls":3},"IPR024810; ","Mab-21 domain; \r"]
["Q9NQT8","Kinesin-like protein KIF13B OS=Homo sapiens OX=9606 GN=KIF13B","KIF13B",202.79,33.147,5.8,10,12,7,1.003,0.912,1.092,1.03,1.104,0.864,0.997,0.954,"nucleus\r","GO:0044700 single organism signaling; GO:0045321 leukocyte activation; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0042110 T cell activation; GO:0010970 transport along microtubule; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0044765 single-organism transport; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0051650 establishment of vesicle localization; GO:0051716 cellular response to stimulus; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:1902582 single-organism intracellular transport; GO:0006810 transport; GO:0099518 vesicle cytoskeletal trafficking; GO:0050789 regulation of biological process; GO:0045664 regulation of neuron differentiation; GO:0048856 anatomical structure development; GO:0010975 regulation of neuron projection development; GO:2000026 regulation of multicellular organismal development; GO:0072384 organelle transport along microtubule; GO:0050794 regulation of cellular process; GO:0051640 organelle localization; GO:0044707 single-multicellular organism process; GO:0046907 intracellular transport; GO:0031344 regulation of cell projection organization; GO:0050896 response to stimulus; GO:0099111 microtubule-based transport; GO:0051239 regulation of multicellular organismal process; GO:0030705 cytoskeleton-dependent intracellular transport; GO:0030154 cell differentiation; GO:1902578 single-organism localization; GO:0051648 vesicle localization; GO:0006886 intracellular protein transport; GO:1902580 single-organism cellular localization; GO:0072386 plus-end-directed organelle transport along microtubule; GO:0007275 multicellular organism development; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0048731 system development; GO:0051960 regulation of nervous system development; GO:0060284 regulation of cell development; GO:0002376 immune system process; GO:0046649 lymphocyte activation; GO:0071702 organic substance transport; GO:0051656 establishment of organelle localization; GO:0007017 microtubule-based process; GO:0050770 regulation of axonogenesis; GO:0047496 vesicle transport along microtubule; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0007018 microtubule-based movement; GO:0070727 cellular macromolecule localization; GO:0072383 plus-end-directed vesicle transport along microtubule; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0001775 cell activation; GO:0006928 movement of cell or subcellular component; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0022604 regulation of cell morphogenesis; GO:0050793 regulation of developmental process; GO:0065007 biological regulation; GO:0050767 regulation of neurogenesis; ","GO:0005874 microtubule; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0099512 supramolecular fiber; GO:0098858 actin-based cell projection; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0015630 microtubule cytoskeleton; GO:0044304 main axon; GO:0005622 intracellular; GO:0044464 cell part; GO:0043005 neuron projection; GO:0033270 paranode region of axon; GO:0097458 neuron part; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0099513 polymeric cytoskeletal fiber; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0005875 microtubule associated complex; GO:0044463 cell projection part; GO:0005829 cytosol; GO:0033267 axon part; GO:0099081 supramolecular polymer; GO:0005871 kinesin complex; GO:0043226 organelle; GO:0030424 axon; GO:0005902 microvillus; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0003774 motor activity; GO:1901265 nucleoside phosphate binding; GO:0019901 protein kinase binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0016887 ATPase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0008092 cytoskeletal protein binding; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0008017 microtubule binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0003777 microtubule motor activity; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0015631 tubulin binding; GO:0071889 14-3-3 protein binding; GO:0000166 nucleotide binding; GO:0019900 kinase binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019899 enzyme binding; GO:0036094 small molecule binding; ","K17914",null,null,"IPR008984; IPR022140; IPR027417; IPR022164; IPR000938; IPR000253; IPR032405; IPR001752; ","SMAD/FHA domain; Kinesin-like KIF1-type; P-loop containing nucleoside triphosphate hydrolase; Kinesin-like; CAP Gly-rich domain; Forkhead-associated (FHA) domain; Kinesin-associated; Kinesin motor domain; \r"]
["Q9NQW8","Cyclic nucleotide-gated cation channel beta-3 OS=Homo sapiens OX=9606 GN=CNGB3","CNGB3",92.165,2.8033,1.5,1,1,1,1.124,0.993,1.011,1.004,0.983,0.901,0.923,0.194,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0034220 ion transmembrane transport; GO:0007601 visual perception; GO:0030001 metal ion transport; GO:0071804 cellular potassium ion transport; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0050877 neurological system process; GO:0051234 establishment of localization; GO:0006813 potassium ion transport; GO:0007165 signal transduction; GO:1902578 single-organism localization; GO:0007154 cell communication; GO:0006812 cation transport; GO:0009987 cellular process; GO:0044765 single-organism transport; GO:0051716 cellular response to stimulus; GO:0007600 sensory perception; GO:0098655 cation transmembrane transport; GO:0003008 system process; GO:0098660 inorganic ion transmembrane transport; GO:0044763 single-organism cellular process; GO:0050953 sensory perception of light stimulus; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0042391 regulation of membrane potential; GO:0006810 transport; GO:0055085 transmembrane transport; GO:0050789 regulation of biological process; GO:0006811 ion transport; GO:0051179 localization; GO:0071805 potassium ion transmembrane transport; GO:0015672 monovalent inorganic cation transport; GO:0098662 inorganic cation transmembrane transport; GO:0065007 biological regulation; ","GO:0005929 cilium; GO:0016020 membrane; GO:0042995 cell projection; GO:0031226 intrinsic component of plasma membrane; GO:0071944 cell periphery; GO:0097730 non-motile cilium; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0005887 integral component of plasma membrane; GO:0044463 cell projection part; GO:1902495 transmembrane transporter complex; GO:0005623 cell; GO:0097731 9+0 non-motile cilium; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0044441 ciliary part; GO:0044464 cell part; GO:0044425 membrane part; GO:0001750 photoreceptor outer segment; GO:0097733 photoreceptor cell cilium; GO:1990351 transporter complex; GO:0097458 neuron part; ","GO:1901265 nucleoside phosphate binding; GO:0022803 passive transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0015077 monovalent inorganic cation transmembrane transporter activity; GO:0015267 channel activity; GO:0030553 cGMP binding; GO:0022891 substrate-specific transmembrane transporter activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0046873 metal ion transmembrane transporter activity; GO:0005267 potassium channel activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0043168 anion binding; GO:0005216 ion channel activity; GO:0022890 inorganic cation transmembrane transporter activity; GO:0019001 guanyl nucleotide binding; GO:0043855 cyclic nucleotide-gated ion channel activity; GO:0017076 purine nucleotide binding; GO:0005215 transporter activity; GO:0015276 ligand-gated ion channel activity; GO:0022834 ligand-gated channel activity; GO:0030551 cyclic nucleotide binding; GO:0015075 ion transmembrane transporter activity; GO:0005223 intracellular cGMP activated cation channel activity; GO:0043167 ion binding; GO:0000166 nucleotide binding; GO:0015079 potassium ion transmembrane transporter activity; GO:0005249 voltage-gated potassium channel activity; GO:0005244 voltage-gated ion channel activity; GO:0060089 molecular transducer activity; GO:0097367 carbohydrate derivative binding; GO:0004872 receptor activity; GO:0022838 substrate-specific channel activity; GO:0022843 voltage-gated cation channel activity; GO:0005261 cation channel activity; GO:0032555 purine ribonucleotide binding; GO:0022836 gated channel activity; GO:0032561 guanyl ribonucleotide binding; GO:0022832 voltage-gated channel activity; GO:0005221 intracellular cyclic nucleotide activated cation channel activity; GO:0008324 cation transmembrane transporter activity; GO:0005217 intracellular ligand-gated ion channel activity; GO:0099600 transmembrane receptor activity; GO:0022857 transmembrane transporter activity; GO:0036094 small molecule binding; ","K04953","CNGB3; cyclic nucleotide gated channel beta 3","hsa04024 cAMP signaling pathway - Homo sapiens (human); ","IPR000595; IPR018490; IPR014710; ","Cyclic nucleotide-binding domain; Cyclic nucleotide-binding-like; RmlC-like jelly roll fold; \r"]
["Q9NR19","Acetyl-coenzyme A synthetase, cytoplasmic OS=Homo sapiens OX=9606 GN=ACSS2","ACSS2",78.579,33.109,13.4,10,11,10,1.301,1.251,1.29,0.774,0.735,0.698,0.574,6.29e-05,"cytoplasm\r","GO:0019427 acetyl-CoA biosynthetic process from acetate; GO:0051188 cofactor biosynthetic process; GO:0006069 ethanol oxidation; GO:0019413 acetate biosynthetic process; GO:1901615 organic hydroxy compound metabolic process; GO:0016053 organic acid biosynthetic process; GO:0006066 alcohol metabolic process; GO:0051790 short-chain fatty acid biosynthetic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0035384 thioester biosynthetic process; GO:0044272 sulfur compound biosynthetic process; GO:0008610 lipid biosynthetic process; GO:0071704 organic substance metabolic process; GO:0006085 acetyl-CoA biosynthetic process; GO:0008152 metabolic process; GO:0006067 ethanol metabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0009108 coenzyme biosynthetic process; GO:0034308 primary alcohol metabolic process; GO:0009987 cellular process; GO:0006083 acetate metabolic process; GO:0019541 propionate metabolic process; GO:0006629 lipid metabolic process; GO:0006790 sulfur compound metabolic process; GO:0044711 single-organism biosynthetic process; GO:0055114 oxidation-reduction process; GO:0071616 acyl-CoA biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0035383 thioester metabolic process; GO:0019542 propionate biosynthetic process; GO:0006732 coenzyme metabolic process; GO:0006631 fatty acid metabolic process; GO:0006084 acetyl-CoA metabolic process; GO:0044238 primary metabolic process; GO:0006633 fatty acid biosynthetic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0006637 acyl-CoA metabolic process; GO:0051186 cofactor metabolic process; GO:0046394 carboxylic acid biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0044283 small molecule biosynthetic process; GO:0019752 carboxylic acid metabolic process; GO:0046459 short-chain fatty acid metabolic process; GO:0006082 organic acid metabolic process; GO:0072330 monocarboxylic acid biosynthetic process; GO:0043436 oxoacid metabolic process; ","GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0016405 CoA-ligase activity; GO:0016874 ligase activity; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016877 ligase activity, forming carbon-sulfur bonds; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003987 acetate-CoA ligase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016208 AMP binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0016878 acid-thiol ligase activity; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K01895","ACSS; acetyl-CoA synthetase [EC:6.2.1.1]","hsa00640 Propanoate metabolism - Homo sapiens (human); hsa00620 Pyruvate metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); ","IPR032387; IPR025110; IPR000873; ","\"Acetyl-coenzyme A synthetase, N-terminal domain; AMP-binding enzyme C-terminal domain; AMP-dependent synthetase/ligase; \"\r"]
["Q9NR28","Diablo homolog, mitochondrial OS=Homo sapiens OX=9606 GN=DIABLO","DIABLO",27.131,14.49,23.4,6,7,6,1.046,1.04,1.078,0.833,0.949,1.062,0.899,0.257,"mitochondria\r","GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0032270 positive regulation of cellular protein metabolic process; GO:0070997 neuron death; GO:0007166 cell surface receptor signaling pathway; GO:0044699 single-organism process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0044093 positive regulation of molecular function; GO:0006915 apoptotic process; GO:0006979 response to oxidative stress; GO:0034599 cellular response to oxidative stress; GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0070887 cellular response to chemical stimulus; GO:0052548 regulation of endopeptidase activity; GO:0051716 cellular response to stimulus; GO:0051402 neuron apoptotic process; GO:0010950 positive regulation of endopeptidase activity; GO:0080090 regulation of primary metabolic process; GO:2000116 regulation of cysteine-type endopeptidase activity; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0031323 regulation of cellular metabolic process; GO:0023052 signaling; GO:0010942 positive regulation of cell death; GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0032268 regulation of cellular protein metabolic process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0052547 regulation of peptidase activity; GO:0010952 positive regulation of peptidase activity; GO:0043068 positive regulation of programmed cell death; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0097191 extrinsic apoptotic signaling pathway; GO:0097190 apoptotic signaling pathway; GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors; GO:2001056 positive regulation of cysteine-type endopeptidase activity; GO:0060255 regulation of macromolecule metabolic process; GO:0043067 regulation of programmed cell death; GO:0043065 positive regulation of apoptotic process; GO:0050896 response to stimulus; GO:0097193 intrinsic apoptotic signaling pathway; GO:0045862 positive regulation of proteolysis; GO:0051345 positive regulation of hydrolase activity; GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0009987 cellular process; GO:0006950 response to stress; GO:0035556 intracellular signal transduction; GO:0036473 cell death in response to oxidative stress; GO:0030162 regulation of proteolysis; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress; GO:0051247 positive regulation of protein metabolic process; GO:0008219 cell death; GO:0051246 regulation of protein metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0012501 programmed cell death; GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0009898 cytoplasmic side of plasma membrane; GO:0098562 cytoplasmic side of membrane; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:0031970 organelle envelope lumen; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0035631 CD40 receptor complex; GO:0043233 organelle lumen; GO:0098552 side of membrane; GO:0043229 intracellular organelle; GO:0031226 intrinsic component of plasma membrane; GO:0044429 mitochondrial part; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0098802 plasma membrane receptor complex; GO:0043235 receptor complex; GO:0005829 cytosol; GO:0016021 integral component of membrane; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044459 plasma membrane part; GO:0005758 mitochondrial intermembrane space; GO:0031975 envelope; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ","K10522","DIABLO; diablo","hsa04210 Apoptosis - Homo sapiens (human); hsa04215 Apoptosis - multiple species - Homo sapiens (human); ","IPR009062; ","Smac/DIABLO-like; \r"]
["Q9NR46","Endophilin-B2 OS=Homo sapiens OX=9606 GN=SH3GLB2","SH3GLB2",43.973,16.308,20.3,8,9,7,0.949,1.061,1.06,0.977,0.99,1.016,0.972,0.517,"cytoplasm\r",null,"GO:0043229 intracellular organelle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0050839 cell adhesion molecule binding; GO:0005515 protein binding; GO:0042802 identical protein binding; GO:0005488 binding; GO:0045296 cadherin binding; ","K21269","SH3GLB2; endophilin-B2","hsa04144 Endocytosis - Homo sapiens (human); ","IPR001452; IPR027267; IPR004148; ","SH3 domain; Arfaptin homology (AH) domain/BAR domain; BAR domain; \r"]
["Q9NR56","Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1","MBNL1",41.817,13.217,13.7,6,8,6,0.933,0.937,0.873,1.127,1.109,1.116,1.222,1E-3,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0006725 cellular aromatic compound metabolic process; GO:0043009 chordate embryonic development; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0048869 cellular developmental process; GO:0045445 myoblast differentiation; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0009653 anatomical structure morphogenesis; GO:0008152 metabolic process; GO:0030154 cell differentiation; GO:0035107 appendage morphogenesis; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0061061 muscle structure development; GO:0060173 limb development; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0007275 multicellular organism development; GO:0009790 embryo development; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0048598 embryonic morphogenesis; GO:0035113 embryonic appendage morphogenesis; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0006396 RNA processing; GO:0010468 regulation of gene expression; GO:0080090 regulation of primary metabolic process; GO:0048731 system development; GO:0009792 embryo development ending in birth or egg hatching; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0044238 primary metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0032501 multicellular organismal process; GO:0043484 regulation of RNA splicing; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:0048736 appendage development; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0001701 in utero embryonic development; GO:0035108 limb morphogenesis; GO:0030326 embryonic limb morphogenesis; GO:0044767 single-organism developmental process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0042692 muscle cell differentiation; GO:0010467 gene expression; GO:0016071 mRNA metabolic process; GO:0048856 anatomical structure development; GO:0065007 biological regulation; ","GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0031974 membrane-enclosed lumen; GO:0005815 microtubule organizing center; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0010494 cytoplasmic stress granule; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005813 centrosome; GO:0035770 ribonucleoprotein granule; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0001067 regulatory region nucleic acid binding; GO:0003725 double-stranded RNA binding; GO:0005488 binding; GO:0043167 ion binding; GO:0001069 regulatory region RNA binding; GO:0003676 nucleic acid binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; ","K14943",null,null,"IPR000571; ","\"Zinc finger, CCCH-type; \"\r"]
["Q9NRG7","Epimerase family protein SDR39U1 OS=Homo sapiens OX=9606 GN=SDR39U1","SDR39U1",34.747,3.5086,2.8,1,1,1,0.954,0.916,0.997,0.987,1.095,1.05,1.092,0.0859,"nucleus\r","GO:0044699 single-organism process; GO:0008152 metabolic process; GO:0055114 oxidation-reduction process; GO:0044710 single-organism metabolic process; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; ","GO:0003824 catalytic activity; GO:0016491 oxidoreductase activity; ","K07071",null,null,"IPR013549; IPR016040; ","Domain of unknown function DUF1731; NAD(P)-binding domain; \r"]
["Q9NRP0","Oligosaccharyltransferase complex subunit OSTC OS=Homo sapiens OX=9606 GN=OSTC","OSTC",16.829,8.9285,8.1,1,4,1,1.069,1.122,1.033,0.924,0.888,0.983,0.867,0.0198,"plasma membrane\r","GO:0043413 macromolecule glycosylation; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0018196 peptidyl-asparagine modification; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:1901135 carbohydrate derivative metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006487 protein N-linked glycosylation; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0070085 glycosylation; GO:0006486 protein glycosylation; GO:0009101 glycoprotein biosynthetic process; GO:0044763 single-organism cellular process; GO:0009100 glycoprotein metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0018193 peptidyl-amino acid modification; GO:0018279 protein N-linked glycosylation via asparagine; GO:0034645 cellular macromolecule biosynthetic process; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0036211 protein modification process; GO:0043412 macromolecule modification; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0008250 oligosaccharyltransferase complex; GO:1990234 transferase complex; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:1902494 catalytic complex; GO:0044432 endoplasmic reticulum part; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; "]
["Q9NRX4","14 kDa phosphohistidine phosphatase OS=Homo sapiens OX=9606 GN=PHPT1","PHPT1",13.832,4.8912,18.4,2,3,2,1.196,1.15,0.947,0.889,0.886,0.958,0.83,0.0762,"cytoplasm\r","GO:0065008 regulation of biological quality; GO:0009968 negative regulation of signal transduction; GO:0040017 positive regulation of locomotion; GO:0050796 regulation of insulin secretion; GO:0023051 regulation of signaling; GO:0051046 regulation of secretion; GO:0002793 positive regulation of peptide secretion; GO:0050858 negative regulation of antigen receptor-mediated signaling pathway; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0008152 metabolic process; GO:0010646 regulation of cell communication; GO:0032879 regulation of localization; GO:0032846 positive regulation of homeostatic process; GO:2000983 regulation of ATP citrate synthase activity; GO:0051493 regulation of cytoskeleton organization; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:2000984 negative regulation of ATP citrate synthase activity; GO:0048522 positive regulation of cellular process; GO:0051272 positive regulation of cellular component movement; GO:0051348 negative regulation of transferase activity; GO:1903530 regulation of secretion by cell; GO:0043086 negative regulation of catalytic activity; GO:0050776 regulation of immune response; GO:0051050 positive regulation of transport; GO:0002683 negative regulation of immune system process; GO:0051339 regulation of lyase activity; GO:0046883 regulation of hormone secretion; GO:0050789 regulation of biological process; GO:1903532 positive regulation of secretion by cell; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0050856 regulation of T cell receptor signaling pathway; GO:0050714 positive regulation of protein secretion; GO:0010817 regulation of hormone levels; GO:0065009 regulation of molecular function; GO:0006464 cellular protein modification process; GO:0002682 regulation of immune system process; GO:0051223 regulation of protein transport; GO:0044092 negative regulation of molecular function; GO:0036211 protein modification process; GO:0051222 positive regulation of protein transport; GO:0051047 positive regulation of secretion; GO:0050794 regulation of cellular process; GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus; GO:0032956 regulation of actin cytoskeleton organization; GO:0044267 cellular protein metabolic process; GO:0050860 negative regulation of T cell receptor signaling pathway; GO:2000147 positive regulation of cell motility; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0032844 regulation of homeostatic process; GO:0035971 peptidyl-histidine dephosphorylation; GO:0090277 positive regulation of peptide hormone secretion; GO:0070201 regulation of establishment of protein localization; GO:0071704 organic substance metabolic process; GO:0060341 regulation of cellular localization; GO:0002791 regulation of peptide secretion; GO:0050854 regulation of antigen receptor-mediated signaling pathway; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:2000145 regulation of cell motility; GO:0023056 positive regulation of signaling; GO:2000249 regulation of actin cytoskeleton reorganization; GO:0051338 regulation of transferase activity; GO:0010647 positive regulation of cell communication; GO:0032880 regulation of protein localization; GO:0050708 regulation of protein secretion; GO:0009987 cellular process; GO:0009966 regulation of signal transduction; GO:0090087 regulation of peptide transport; GO:0032024 positive regulation of insulin secretion; GO:0051270 regulation of cellular component movement; GO:0051049 regulation of transport; GO:0051350 negative regulation of lyase activity; GO:0033043 regulation of organelle organization; GO:0032970 regulation of actin filament-based process; GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus; GO:0048585 negative regulation of response to stimulus; GO:0006470 protein dephosphorylation; GO:0044238 primary metabolic process; GO:0016311 dephosphorylation; GO:0048518 positive regulation of biological process; GO:1904951 positive regulation of establishment of protein localization; GO:0006793 phosphorus metabolic process; GO:0046887 positive regulation of hormone secretion; GO:0090276 regulation of peptide hormone secretion; GO:0051128 regulation of cellular component organization; GO:0043412 macromolecule modification; GO:0040012 regulation of locomotion; GO:0048584 positive regulation of response to stimulus; GO:0065007 biological regulation; ","GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0008200 ion channel inhibitor activity; GO:0016791 phosphatase activity; GO:0099106 ion channel regulator activity; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0004721 phosphoprotein phosphatase activity; GO:0098772 molecular function regulator; GO:0005246 calcium channel regulator activity; GO:0016248 channel inhibitor activity; GO:0019855 calcium channel inhibitor activity; GO:0003824 catalytic activity; GO:0042578 phosphoric ester hydrolase activity; GO:0016247 channel regulator activity; GO:0005488 binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0044325 ion channel binding; GO:0008969 phosphohistidine phosphatase activity; ","K01112"]
["Q9NRY5","Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2","FAM114A2",55.468,19.521,12.1,5,5,5,0.974,0.9,1.028,0.946,1.067,0.967,1.027,0.645,"nucleus\r",null,null,"GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:1901265 nucleoside phosphate binding; GO:0005488 binding; GO:0000166 nucleotide binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; "]
["Q9NS86","LanC-like protein 2 OS=Homo sapiens OX=9606 GN=LANCL2","LANCL2",50.854,36.303,17.1,7,7,7,1.024,0.972,0.996,1.029,1.016,1.028,1.027,0.159,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0060255 regulation of macromolecule metabolic process; GO:0023051 regulation of signaling; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0051253 negative regulation of RNA metabolic process; GO:0009789 positive regulation of abscisic acid-activated signaling pathway; GO:0045892 negative regulation of transcription, DNA-templated; GO:2001141 regulation of RNA biosynthetic process; GO:0010646 regulation of cell communication; GO:0023056 positive regulation of signaling; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0010647 positive regulation of cell communication; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:1901419 regulation of response to alcohol; GO:0009966 regulation of signal transduction; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0010468 regulation of gene expression; GO:0006355 regulation of transcription, DNA-templated; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0010629 negative regulation of gene expression; GO:0048522 positive regulation of cellular process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0009892 negative regulation of metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0009890 negative regulation of biosynthetic process; GO:0050789 regulation of biological process; GO:0048583 regulation of response to stimulus; GO:1902679 negative regulation of RNA biosynthetic process; GO:0019222 regulation of metabolic process; GO:1901421 positive regulation of response to alcohol; GO:0009967 positive regulation of signal transduction; GO:0031327 negative regulation of cellular biosynthetic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0048584 positive regulation of response to stimulus; GO:0009787 regulation of abscisic acid-activated signaling pathway; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005938 cell cortex; GO:0043232 intracellular non-membrane-bounded organelle; GO:0071944 cell periphery; GO:0044430 cytoskeletal part; GO:0099568 cytoplasmic region; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0030863 cortical cytoskeleton; GO:0030864 cortical actin cytoskeleton; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0015629 actin cytoskeleton; GO:0044422 organelle part; GO:0005886 plasma membrane; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0044448 cell cortex part; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:1901981 phosphatidylinositol phosphate binding; GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003824 catalytic activity; GO:0032266 phosphatidylinositol-3-phosphate binding; GO:0032553 ribonucleotide binding; GO:0010314 phosphatidylinositol-5-phosphate binding; GO:0005488 binding; GO:0005543 phospholipid binding; GO:0035091 phosphatidylinositol binding; GO:0032550 purine ribonucleoside binding; GO:0008289 lipid binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032561 guanyl ribonucleotide binding; GO:0070273 phosphatidylinositol-4-phosphate binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ",{"$nulls":3},"IPR012341; ","Six-hairpin glycosidase; \r"]
["Q9NSK0","Kinesin light chain 4 OS=Homo sapiens OX=9606 GN=KLC4","KLC4",68.639,1.9087,5.2,3,3,1,0.93,1.056,1.032,1.096,1.012,0.887,0.992,0.899,"nucleus\r",null,"GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0005874 microtubule; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0005875 microtubule associated complex; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0099081 supramolecular polymer; GO:0005871 kinesin complex; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0005856 cytoskeleton; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0043234 protein complex; ","GO:0016462 pyrophosphatase activity; GO:0003774 motor activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0017111 nucleoside-triphosphatase activity; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0003777 microtubule motor activity; ","K10407","KLC; kinesin light chain","hsa05132 Salmonella infection - Homo sapiens (human); ","IPR011990; IPR013026; ","Tetratricopeptide-like helical domain; Tetratricopeptide repeat-containing domain; \r"]
["Q9NSY2","StAR-related lipid transfer protein 5 OS=Homo sapiens OX=9606 GN=STARD5","STARD5",23.794,13.734,17.4,3,5,3,0.863,0.927,0.869,1.144,1.117,1.173,1.291,0.000675,"extracellular\r","GO:0015918 sterol transport; GO:0015850 organic hydroxy compound transport; GO:0006869 lipid transport; GO:0015721 bile acid and bile salt transport; GO:0030301 cholesterol transport; GO:0044699 single-organism process; GO:0010876 lipid localization; GO:0071702 organic substance transport; GO:0070508 cholesterol import; GO:0046942 carboxylic acid transport; GO:0015849 organic acid transport; GO:0051234 establishment of localization; GO:0006810 transport; GO:0006820 anion transport; GO:0015711 organic anion transport; GO:1902578 single-organism localization; GO:0015718 monocarboxylic acid transport; GO:0006811 ion transport; GO:0035376 sterol import; GO:0051179 localization; GO:0033036 macromolecule localization; GO:0044765 single-organism transport; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005829 cytosol; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044444 cytoplasmic part; ","GO:0015485 cholesterol binding; GO:0032934 sterol binding; GO:0043167 ion binding; GO:0005319 lipid transporter activity; GO:0043177 organic acid binding; GO:0022892 substrate-specific transporter activity; GO:0033293 monocarboxylic acid binding; GO:0005496 steroid binding; GO:0097159 organic cyclic compound binding; GO:0032052 bile acid binding; GO:0031406 carboxylic acid binding; GO:0017127 cholesterol transporter activity; GO:0005488 binding; GO:0043178 alcohol binding; GO:0008289 lipid binding; GO:0015248 sterol transporter activity; GO:0043168 anion binding; GO:0005215 transporter activity; GO:0036094 small molecule binding; ",{"$nulls":3},"IPR002913; IPR023393; ","START domain; START-like domain; \r"]
["Q9NT62","Ubiquitin-like-conjugating enzyme ATG3 OS=Homo sapiens OX=9606 GN=ATG3","ATG3",35.864,26.078,15,4,7,4,0.917,0.964,0.931,0.943,1.173,1.068,1.132,0.137,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0060627 regulation of vesicle-mediated transport; GO:1905037 autophagosome organization; GO:0060491 regulation of cell projection assembly; GO:0051129 negative regulation of cellular component organization; GO:0000422 mitophagy; GO:0044699 single-organism process; GO:1903008 organelle disassembly; GO:0044804 nucleophagy; GO:0006914 autophagy; GO:0044237 cellular metabolic process; GO:1902115 regulation of organelle assembly; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0022607 cellular component assembly; GO:0032879 regulation of localization; GO:0006915 apoptotic process; GO:0007005 mitochondrion organization; GO:0007033 vacuole organization; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0050764 regulation of phagocytosis; GO:0016236 macroautophagy; GO:0051051 negative regulation of transport; GO:0072657 protein localization to membrane; GO:0044763 single-organism cellular process; GO:0070647 protein modification by small protein conjugation or removal; GO:0006810 transport; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0036211 protein modification process; GO:0000045 autophagosome assembly; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0044267 cellular protein metabolic process; GO:0044087 regulation of cellular component biogenesis; GO:0031344 regulation of cell projection organization; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0050765 negative regulation of phagocytosis; GO:0071704 organic substance metabolic process; GO:0045806 negative regulation of endocytosis; GO:0070925 organelle assembly; GO:0006886 intracellular protein transport; GO:0044248 cellular catabolic process; GO:0034613 cellular protein localization; GO:0090150 establishment of protein localization to membrane; GO:0009987 cellular process; GO:0043653 mitochondrial fragmentation involved in apoptotic process; GO:1902017 regulation of cilium assembly; GO:0030100 regulation of endocytosis; GO:0008637 apoptotic mitochondrial changes; GO:0016567 protein ubiquitination; GO:0044712 single-organism catabolic process; GO:0051049 regulation of transport; GO:0033043 regulation of organelle organization; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0061726 mitochondrion disassembly; GO:0032446 protein modification by small protein conjugation; GO:0008219 cell death; GO:0006996 organelle organization; GO:0022411 cellular component disassembly; GO:0012501 programmed cell death; GO:0051128 regulation of cellular component organization; GO:0043412 macromolecule modification; GO:0051179 localization; GO:0009056 catabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0000153 cytoplasmic ubiquitin ligase complex; GO:1902494 catalytic complex; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:1990234 transferase complex; GO:0005829 cytosol; GO:0005623 cell; GO:0000151 ubiquitin ligase complex; GO:0044444 cytoplasmic part; ","GO:0019776 Atg8 ligase activity; GO:0019787 ubiquitin-like protein transferase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016874 ligase activity; GO:0019777 Atg12 transferase activity; GO:0005515 protein binding; GO:0016740 transferase activity; GO:0019899 enzyme binding; ","K08343","ATG3; ubiquitin-like-conjugating enzyme ATG3","hsa04136 Autophagy - other - Homo sapiens (human); hsa04140 Autophagy - animal - Homo sapiens (human); hsa05167 Kaposi's sarcoma-associated herpesvirus infection - Homo sapiens (human); ","IPR007135; IPR019461; IPR007134; ","\"Autophagy-related protein 3; Autophagy-related protein 3, C-terminal; Autophagy-related protein 3, N-terminal; \"\r"]
["Q9NTJ4","Alpha-mannosidase 2C1 OS=Homo sapiens OX=9606 GN=MAN2C1","MAN2C1",115.83,6.9936,4.2,5,5,5,1.07,1.07,1.011,0.926,1.071,0.972,0.942,0.262,"nucleus\r","GO:0044724 single-organism carbohydrate catabolic process; GO:0044712 single-organism catabolic process; GO:0006517 protein deglycosylation; GO:0044281 small molecule metabolic process; GO:0009313 oligosaccharide catabolic process; GO:0044267 cellular protein metabolic process; GO:0006013 mannose metabolic process; GO:0044699 single-organism process; GO:0009100 glycoprotein metabolic process; GO:0005975 carbohydrate metabolic process; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0016052 carbohydrate catabolic process; GO:0071704 organic substance metabolic process; GO:1901575 organic substance catabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0008152 metabolic process; GO:0044710 single-organism metabolic process; GO:0005996 monosaccharide metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0006464 cellular protein modification process; GO:0009311 oligosaccharide metabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:0009056 catabolic process; GO:0009987 cellular process; GO:0019318 hexose metabolic process; ","GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0005773 vacuole; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0015923 mannosidase activity; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0004559 alpha-mannosidase activity; GO:0016798 hydrolase activity, acting on glycosyl bonds; GO:0030246 carbohydrate binding; GO:0043169 cation binding; GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds; GO:0046872 metal ion binding; GO:0016787 hydrolase activity; GO:0008270 zinc ion binding; ","K01191","MAN2C1; alpha-mannosidase [EC:3.2.1.24]","hsa00511 Other glycan degradation - Homo sapiens (human); ","IPR011013; IPR027291; IPR011330; IPR028995; IPR000602; IPR011682; IPR015341; ","\"Galactose mutarotase-like domain; Glycoside hydrolase 38/57, N-terminal domain; Glycoside hydrolase/deacetylase, beta/alpha-barrel; Glycoside hydrolase families 57/38, central domain; Glycoside hydrolase family 38, N-terminal domain; Glycosyl hydrolase family 38, C-terminal; Glycoside hydrolase family 38, central domain; \"\r"]
["Q9NTX5","Ethylmalonyl-CoA decarboxylase OS=Homo sapiens OX=9606 GN=ECHDC1","ECHDC1",33.698,64.182,41,10,14,10,1.056,1.125,1.093,0.936,0.9,0.903,0.837,0.0013,"cytoplasm\r","GO:0034440 lipid oxidation; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0030258 lipid modification; GO:0044248 cellular catabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0009987 cellular process; GO:0006629 lipid metabolic process; GO:0016042 lipid catabolic process; GO:0019395 fatty acid oxidation; GO:0055114 oxidation-reduction process; GO:0044712 single-organism catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006635 fatty acid beta-oxidation; GO:0072329 monocarboxylic acid catabolic process; GO:0044282 small molecule catabolic process; GO:0006631 fatty acid metabolic process; GO:0044238 primary metabolic process; GO:0046395 carboxylic acid catabolic process; GO:1901575 organic substance catabolic process; GO:0044710 single-organism metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0016054 organic acid catabolic process; GO:0044242 cellular lipid catabolic process; GO:0006082 organic acid metabolic process; GO:0009062 fatty acid catabolic process; GO:0009056 catabolic process; GO:0043436 oxoacid metabolic process; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0004492 methylmalonyl-CoA decarboxylase activity; GO:0003824 catalytic activity; GO:0016830 carbon-carbon lyase activity; GO:0016831 carboxy-lyase activity; GO:0016829 lyase activity; GO:0016836 hydro-lyase activity; GO:0016835 carbon-oxygen lyase activity; GO:0004300 enoyl-CoA hydratase activity; ","K18426","ECHDC1; ethylmalonyl-CoA/methylmalonyl-CoA decarboxylase [EC:4.1.1.94 4.1.1.41]","hsa00640 Propanoate metabolism - Homo sapiens (human); ","IPR029045; ","ClpP/crotonase-like domain; \r"]
["Q9NUB1","Acetyl-coenzyme A synthetase 2-like, mitochondrial OS=Homo sapiens OX=9606 GN=ACSS1","ACSS1",74.856,28.229,4.6,2,3,2,0.994,0.914,1.022,1.031,0.957,1.086,1.049,0.391,"mitochondria\r","GO:0019427 acetyl-CoA biosynthetic process from acetate; GO:0051188 cofactor biosynthetic process; GO:0006069 ethanol oxidation; GO:0019413 acetate biosynthetic process; GO:1901615 organic hydroxy compound metabolic process; GO:0016053 organic acid biosynthetic process; GO:0006066 alcohol metabolic process; GO:0051790 short-chain fatty acid biosynthetic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0035384 thioester biosynthetic process; GO:0044272 sulfur compound biosynthetic process; GO:0008610 lipid biosynthetic process; GO:0071704 organic substance metabolic process; GO:0006085 acetyl-CoA biosynthetic process; GO:0008152 metabolic process; GO:0006067 ethanol metabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0009108 coenzyme biosynthetic process; GO:0034308 primary alcohol metabolic process; GO:0009987 cellular process; GO:0006083 acetate metabolic process; GO:0019541 propionate metabolic process; GO:0006629 lipid metabolic process; GO:0006790 sulfur compound metabolic process; GO:0044711 single-organism biosynthetic process; GO:0055114 oxidation-reduction process; GO:0071616 acyl-CoA biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0035383 thioester metabolic process; GO:0019542 propionate biosynthetic process; GO:0006732 coenzyme metabolic process; GO:0006631 fatty acid metabolic process; GO:0006084 acetyl-CoA metabolic process; GO:0044238 primary metabolic process; GO:0006633 fatty acid biosynthetic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0006637 acyl-CoA metabolic process; GO:0051186 cofactor metabolic process; GO:0046394 carboxylic acid biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0044283 small molecule biosynthetic process; GO:0019752 carboxylic acid metabolic process; GO:0046459 short-chain fatty acid metabolic process; GO:0006082 organic acid metabolic process; GO:0072330 monocarboxylic acid biosynthetic process; GO:0043436 oxoacid metabolic process; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0016405 CoA-ligase activity; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016874 ligase activity; GO:0005515 protein binding; GO:0016877 ligase activity, forming carbon-sulfur bonds; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003987 acetate-CoA ligase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016208 AMP binding; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0016878 acid-thiol ligase activity; ","K01895","ACSS; acetyl-CoA synthetase [EC:6.2.1.1]","hsa00640 Propanoate metabolism - Homo sapiens (human); hsa00620 Pyruvate metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); ","IPR032387; IPR025110; IPR000873; ","\"Acetyl-coenzyme A synthetase, N-terminal domain; AMP-binding enzyme C-terminal domain; AMP-dependent synthetase/ligase; \"\r"]
["Q9NUL5","Repressor of yield of DENV protein OS=Homo sapiens OX=9606 GN=RYDEN","RYDEN",33.11,2.5078,3.8,1,1,1,0.85,0.994,0.928,1.086,1.067,1.074,1.164,0.0776,"nucleus\r","GO:0050794 regulation of cellular process; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0002252 immune effector process; GO:0098542 defense response to other organism; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0043207 response to external biotic stimulus; GO:0044764 multi-organism cellular process; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0045087 innate immune response; GO:1903901 negative regulation of viral life cycle; GO:0009607 response to biotic stimulus; GO:0009605 response to external stimulus; GO:0016032 viral process; GO:0044419 interspecies interaction between organisms; GO:0009987 cellular process; GO:0048525 negative regulation of viral process; GO:0006950 response to stress; GO:0034097 response to cytokine; GO:0043900 regulation of multi-organism process; GO:0050792 regulation of viral process; GO:0034340 response to type I interferon; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0002376 immune system process; GO:0045071 negative regulation of viral genome replication; GO:0045069 regulation of viral genome replication; GO:0010033 response to organic substance; GO:0034341 response to interferon-gamma; GO:0034342 response to type III interferon; GO:0051704 multi-organism process; GO:0043901 negative regulation of multi-organism process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0051607 defense response to virus; GO:0006952 defense response; GO:1903900 regulation of viral life cycle; GO:0006955 immune response; GO:0009615 response to virus; GO:0065007 biological regulation; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005515 protein binding; GO:0005488 binding; GO:0003676 nucleic acid binding; "]
["Q9NUQ7","Ufm1-specific protease 2 OS=Homo sapiens OX=9606 GN=UFSP2","UFSP2",53.261,32.94,7.5,2,2,2,1.026,0.993,1.057,0.977,0.975,0.982,0.954,0.123,"cytoskeleton\r","GO:0050794 regulation of cellular process; GO:0023051 regulation of signaling; GO:0044238 primary metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0010646 regulation of cell communication; GO:0050789 regulation of biological process; GO:0033146 regulation of intracellular estrogen receptor signaling pathway; GO:0048583 regulation of response to stimulus; GO:0006508 proteolysis; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0033143 regulation of intracellular steroid hormone receptor signaling pathway; GO:0009966 regulation of signal transduction; GO:0065007 biological regulation; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0005783 endoplasmic reticulum; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:0008233 peptidase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0071567 UFM1 hydrolase activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0019783 ubiquitin-like protein-specific protease activity; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0008234 cysteine-type peptidase activity; GO:0016790 thiolester hydrolase activity; ","K01376"]
["Q9NUV9","GTPase IMAP family member 4 OS=Homo sapiens OX=9606 GN=GIMAP4","GIMAP4",37.533,12.306,17.9,7,7,7,1.038,0.996,1.169,0.82,1.071,0.915,0.876,0.21,"cytoplasm\r",null,"GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0000166 nucleotide binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0036094 small molecule binding; ",{"$nulls":3},"IPR006703; IPR027417; ","AIG1-type guanine nucleotide-binding (G) domain; P-loop containing nucleoside triphosphate hydrolase; \r"]
["Q9NVA2","Septin-11 OS=Homo sapiens OX=9606 GN=SEPT11","SEPT11",49.398,159.58,37.8,14,26,5,1.107,1.145,1.136,0.956,0.845,0.866,0.787,0.00352,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0016043 cellular component organization; GO:0071822 protein complex subunit organization; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0051259 protein oligomerization; GO:0043933 macromolecular complex subunit organization; GO:0051291 protein heterooligomerization; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0051301 cell division; GO:0070271 protein complex biogenesis; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; ","GO:0030425 dendrite; GO:0044421 extracellular region part; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0043197 dendritic spine; GO:0044422 organelle part; GO:0032432 actin filament bundle; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0044309 neuron spine; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0001725 stress fiber; GO:0043227 membrane-bounded organelle; GO:0042641 actomyosin; GO:0097458 neuron part; GO:0044456 synapse part; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0097517 contractile actin filament bundle; GO:0044463 cell projection part; GO:0005576 extracellular region; GO:0015629 actin cytoskeleton; GO:0045202 synapse; GO:0030424 axon; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0098794 postsynapse; GO:0043230 extracellular organelle; ","GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0036094 small molecule binding; ","K16939","SEPT6_8_11; septin 6/8/11","hsa05100 Bacterial invasion of epithelial cells - Homo sapiens (human); ","IPR027417; IPR030379; ","P-loop containing nucleoside triphosphate hydrolase; Septin-type guanine nucleotide-binding (G) domain; \r"]
["Q9NVD7","Alpha-parvin OS=Homo sapiens OX=9606 GN=PARVA","PARVA",42.243,78.914,23.9,8,15,6,1.127,1.139,1.07,0.863,0.913,0.89,0.799,0.000896,"cyto_nucl\r","GO:0044085 cellular component biogenesis; GO:0030048 actin filament-based movement; GO:0003148 outflow tract septum morphogenesis; GO:0065008 regulation of biological quality; GO:0070252 actin-mediated cell contraction; GO:0051674 localization of cell; GO:0001568 blood vessel development; GO:0048869 cellular developmental process; GO:0032989 cellular component morphogenesis; GO:0060271 cilium assembly; GO:0044699 single-organism process; GO:0034113 heterotypic cell-cell adhesion; GO:0044782 cilium organization; GO:0022610 biological adhesion; GO:0009605 response to external stimulus; GO:0001525 angiogenesis; GO:0034446 substrate adhesion-dependent cell spreading; GO:0030036 actin cytoskeleton organization; GO:0016337 single organismal cell-cell adhesion; GO:0007507 heart development; GO:0022607 cellular component assembly; GO:0008360 regulation of cell shape; GO:0003151 outflow tract morphogenesis; GO:0007155 cell adhesion; GO:0048514 blood vessel morphogenesis; GO:0070887 cellular response to chemical stimulus; GO:0002040 sprouting angiogenesis; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0071670 smooth muscle cell chemotaxis; GO:0003007 heart morphogenesis; GO:0098609 cell-cell adhesion; GO:0044763 single-organism cellular process; GO:0001944 vasculature development; GO:0007163 establishment or maintenance of cell polarity; GO:0048870 cell motility; GO:0006935 chemotaxis; GO:0032501 multicellular organismal process; GO:0000902 cell morphogenesis; GO:0031532 actin cytoskeleton reorganization; GO:1902589 single-organism organelle organization; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0030030 cell projection organization; GO:0098602 single organism cell adhesion; GO:0009887 animal organ morphogenesis; GO:0042330 taxis; GO:0040011 locomotion; GO:0048856 anatomical structure development; GO:0050794 regulation of cellular process; GO:0072359 circulatory system development; GO:0044707 single-multicellular organism process; GO:0016477 cell migration; GO:0016043 cellular component organization; GO:0014909 smooth muscle cell migration; GO:0060326 cell chemotaxis; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0000904 cell morphogenesis involved in differentiation; GO:0060411 cardiac septum morphogenesis; GO:0009653 anatomical structure morphogenesis; GO:0030154 cell differentiation; GO:0070925 organelle assembly; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0009987 cellular process; GO:0048731 system development; GO:0003279 cardiac septum development; GO:0072358 cardiovascular system development; GO:0003206 cardiac chamber morphogenesis; GO:0030031 cell projection assembly; GO:0003205 cardiac chamber development; GO:0031589 cell-substrate adhesion; GO:0044767 single-organism developmental process; GO:0006996 organelle organization; GO:0022603 regulation of anatomical structure morphogenesis; GO:0030029 actin filament-based process; GO:0006928 movement of cell or subcellular component; GO:0014812 muscle cell migration; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0022604 regulation of cell morphogenesis; GO:0050793 regulation of developmental process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0043232 intracellular non-membrane-bounded organelle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0030016 myofibril; GO:0005737 cytoplasm; GO:0070161 anchoring junction; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0030018 Z disc; GO:0005829 cytosol; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0031674 I band; GO:0044422 organelle part; GO:0005886 plasma membrane; GO:0099081 supramolecular polymer; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0043226 organelle; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:0043292 contractile fiber; GO:0030017 sarcomere; GO:0044449 contractile fiber part; GO:0030055 cell-substrate junction; GO:0005924 cell-substrate adherens junction; GO:0044444 cytoplasmic part; ","GO:0003779 actin binding; GO:0050839 cell adhesion molecule binding; GO:0005515 protein binding; GO:0008092 cytoskeletal protein binding; GO:0005488 binding; GO:0045296 cadherin binding; ","K06275","PARV; parvin","hsa04510 Focal adhesion - Homo sapiens (human); ","IPR001715; ","Calponin homology domain; \r"]
["Q9NVI7","ATPase family AAA domain-containing protein 3A OS=Homo sapiens OX=9606 GN=ATAD3A","ATAD3A",71.368,12.423,7.9,6,7,6,0.951,0.917,0.866,1.124,1.026,1.072,1.178,0.0123,"cyto_nucl\r","GO:0050794 regulation of cellular process; GO:0010941 regulation of cell death; GO:0043069 negative regulation of programmed cell death; GO:0016049 cell growth; GO:0044763 single-organism cellular process; GO:0043067 regulation of programmed cell death; GO:0044699 single-organism process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0050789 regulation of biological process; GO:0043066 negative regulation of apoptotic process; GO:0060548 negative regulation of cell death; GO:0009987 cellular process; GO:0040007 growth; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0043233 organelle lumen; GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0042645 mitochondrial nucleoid; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0016021 integral component of membrane; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031975 envelope; GO:0009295 nucleoid; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K17681",null,null,"IPR003959; IPR003593; IPR021911; IPR027417; ","\"ATPase, AAA-type, core; AAA+ ATPase domain; ATPase family AAA domain-containing protein 3, domain of unknown function DUF3523; P-loop containing nucleoside triphosphate hydrolase; \"\r"]
["Q9NVJ2","ADP-ribosylation factor-like protein 8B OS=Homo sapiens OX=9606 GN=ARL8B","ARL8B",21.539,16.009,17.7,3,9,2,0.944,0.893,0.955,1.076,1.004,0.983,1.097,0.0544,"cytoplasm\r","GO:0051640 organelle localization; GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0051716 cellular response to stimulus; GO:0007059 chromosome segregation; GO:0035556 intracellular signal transduction; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0007264 small GTPase mediated signal transduction; GO:0023052 signaling; GO:0050896 response to stimulus; GO:0051641 cellular localization; GO:0007165 signal transduction; GO:0050789 regulation of biological process; GO:0007154 cell communication; GO:0051301 cell division; GO:0051179 localization; GO:0009987 cellular process; GO:0007049 cell cycle; GO:0032418 lysosome localization; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0051233 spindle midzone; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005765 lysosomal membrane; GO:0070062 extracellular exosome; GO:0005856 cytoskeleton; GO:0015630 microtubule cytoskeleton; GO:0031902 late endosome membrane; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0000323 lytic vacuole; GO:0010008 endosome membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0005770 late endosome; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0030496 midbody; GO:0044440 endosomal part; GO:0012505 endomembrane system; GO:0005819 spindle; GO:0005576 extracellular region; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0048487 beta-tubulin binding; GO:0043014 alpha-tubulin binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0008092 cytoskeletal protein binding; GO:0019003 GDP binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0003924 GTPase activity; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0017076 purine nucleotide binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0015631 tubulin binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0032561 guanyl ribonucleotide binding; GO:0036094 small molecule binding; ","K07955",null,null,"IPR005225; IPR027417; ","Small GTP-binding protein domain; P-loop containing nucleoside triphosphate hydrolase; \r"]
["Q9NVS9","Pyridoxine-5'-phosphate oxidase OS=Homo sapiens OX=9606 GN=PNPO","PNPO",29.988,6.5234,11.5,2,2,2,1.024,1.112,0.96,0.997,0.977,0.948,0.944,0.279,"mitochondria\r","GO:0051188 cofactor biosynthetic process; GO:0009110 vitamin biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:1901615 organic hydroxy compound metabolic process; GO:0042822 pyridoxal phosphate metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:0072524 pyridine-containing compound metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0072525 pyridine-containing compound biosynthetic process; GO:0008152 metabolic process; GO:0006766 vitamin metabolic process; GO:0046483 heterocycle metabolic process; GO:0008614 pyridoxine metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0042364 water-soluble vitamin biosynthetic process; GO:0042823 pyridoxal phosphate biosynthetic process; GO:0009108 coenzyme biosynthetic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0046184 aldehyde biosynthetic process; GO:0009987 cellular process; GO:0006767 water-soluble vitamin metabolic process; GO:0042816 vitamin B6 metabolic process; GO:0008615 pyridoxine biosynthetic process; GO:0018130 heterocycle biosynthetic process; GO:0044711 single-organism biosynthetic process; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006081 cellular aldehyde metabolic process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0042819 vitamin B6 biosynthetic process; GO:0006732 coenzyme metabolic process; GO:1901617 organic hydroxy compound biosynthetic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0051186 cofactor metabolic process; GO:0090407 organophosphate biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0044283 small molecule biosynthetic process; GO:0019637 organophosphate metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0004733 pyridoxamine-phosphate oxidase activity; GO:1901265 nucleoside phosphate binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0048037 cofactor binding; GO:0016491 oxidoreductase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0097367 carbohydrate derivative binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0043168 anion binding; GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors; GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor; GO:0010181 FMN binding; GO:0036094 small molecule binding; ","K00275","pdxH; pyridoxamine 5'-phosphate oxidase [EC:1.4.3.5]","hsa00750 Vitamin B6 metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR019576; IPR012349; IPR011576; ","\"Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal; FMN-binding split barrel; Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain; \"\r"]
["Q9NVU0","DNA-directed RNA polymerase III subunit RPC5 OS=Homo sapiens OX=9606 GN=POLR3E","POLR3E",79.897,2.1793,1.4,1,1,1,0.997,0.984,1.174,0.839,1.054,0.957,0.903,0.304,"cyto_nucl\r","GO:0032481 positive regulation of type I interferon production; GO:0032479 regulation of type I interferon production; GO:0006725 cellular aromatic compound metabolic process; GO:0002252 immune effector process; GO:0097659 nucleic acid-templated transcription; GO:0001819 positive regulation of cytokine production; GO:0098542 defense response to other organism; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0051707 response to other organism; GO:0045087 innate immune response; GO:0051239 regulation of multicellular organismal process; GO:0071704 organic substance metabolic process; GO:0009607 response to biotic stimulus; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0051240 positive regulation of multicellular organismal process; GO:0016032 viral process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0044419 interspecies interaction between organisms; GO:0009987 cellular process; GO:0018130 heterocycle biosynthetic process; GO:0006950 response to stress; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0002376 immune system process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0051704 multi-organism process; GO:0016070 RNA metabolic process; GO:0050789 regulation of biological process; GO:0034645 cellular macromolecule biosynthetic process; GO:0090304 nucleic acid metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0051607 defense response to virus; GO:0006351 transcription, DNA-templated; GO:0044260 cellular macromolecule metabolic process; GO:0001817 regulation of cytokine production; GO:0010467 gene expression; GO:0006952 defense response; GO:0006955 immune response; GO:1901362 organic cyclic compound biosynthetic process; GO:0009615 response to virus; GO:0006383 transcription from RNA polymerase III promoter; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0000428 DNA-directed RNA polymerase complex; GO:0055029 nuclear DNA-directed RNA polymerase complex; GO:0061695 transferase complex, transferring phosphorus-containing groups; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0030880 RNA polymerase complex; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:1990234 transferase complex; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0005666 DNA-directed RNA polymerase III complex; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0003899 DNA-directed 5'-3' RNA polymerase activity; GO:0016779 nucleotidyltransferase activity; GO:0034062 5'-3' RNA polymerase activity; GO:0016740 transferase activity; GO:0003824 catalytic activity; GO:0097747 RNA polymerase activity; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K14721","RPC5; DNA-directed RNA polymerase III subunit RPC5","hsa04623 Cytosolic DNA-sensing pathway - Homo sapiens (human); hsa00230 Purine metabolism - Homo sapiens (human); hsa03020 RNA polymerase - Homo sapiens (human); hsa00240 Pyrimidine metabolism - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); "]
["Q9NWB6","Arginine and glutamate-rich protein 1 OS=Homo sapiens OX=9606 GN=ARGLU1","ARGLU1",33.216,3.9105,8.4,3,3,3,0.942,0.947,0.957,0.96,1.095,1.096,1.107,0.153,"nucleus\r","GO:0050794 regulation of cellular process; GO:0006725 cellular aromatic compound metabolic process; GO:0097659 nucleic acid-templated transcription; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0006355 regulation of transcription, DNA-templated; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0044238 primary metabolic process; GO:0051252 regulation of RNA metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0034645 cellular macromolecule biosynthetic process; GO:0090304 nucleic acid metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006351 transcription, DNA-templated; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0010467 gene expression; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0050839 cell adhesion molecule binding; GO:0005515 protein binding; GO:0005488 binding; GO:0045296 cadherin binding; ","K13173"]
["Q9NWC5","Transmembrane protein 45A OS=Homo sapiens OX=9606 GN=TMEM45A","TMEM45A",31.679,2.9908,3.6,1,1,1,0.696,0.692,0.796,1.179,1.287,1.318,1.733,0.00064,"plasma membrane\r",null,"GO:0031224 intrinsic component of membrane; GO:0016020 membrane; GO:0016021 integral component of membrane; GO:0044425 membrane part; "]
["Q9NWU1","3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial OS=Homo sapiens OX=9606 GN=OXSM","OXSM",48.842,4.1279,3.3,1,1,1,1.053,1.109,1.038,0.961,0.941,0.916,0.881,0.00654,"mitochondria\r","GO:0016053 organic acid biosynthetic process; GO:0051790 short-chain fatty acid biosynthetic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008610 lipid biosynthetic process; GO:0008152 metabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0051791 medium-chain fatty acid metabolic process; GO:0009987 cellular process; GO:0006629 lipid metabolic process; GO:0006790 sulfur compound metabolic process; GO:0044711 single-organism biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0035383 thioester metabolic process; GO:0006732 coenzyme metabolic process; GO:0006631 fatty acid metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0006633 fatty acid biosynthetic process; GO:0006637 acyl-CoA metabolic process; GO:0044249 cellular biosynthetic process; GO:0051186 cofactor metabolic process; GO:0046394 carboxylic acid biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0044283 small molecule biosynthetic process; GO:0019752 carboxylic acid metabolic process; GO:0051792 medium-chain fatty acid biosynthetic process; GO:0046459 short-chain fatty acid metabolic process; GO:0006082 organic acid metabolic process; GO:0072330 monocarboxylic acid biosynthetic process; GO:0043436 oxoacid metabolic process; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005829 cytosol; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044444 cytoplasmic part; ","GO:0016746 transferase activity, transferring acyl groups; GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity; GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups; GO:0003824 catalytic activity; GO:0016740 transferase activity; GO:0004312 fatty acid synthase activity; ","K09458","fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]","hsa00780 Biotin metabolism - Homo sapiens (human); hsa00061 Fatty acid biosynthesis - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa01212 Fatty acid metabolism - Homo sapiens (human); ","IPR020841; IPR016039; IPR014031; IPR014030; ","\"Polyketide synthase, beta-ketoacyl synthase domain; Thiolase-like; Beta-ketoacyl synthase, C-terminal; Beta-ketoacyl synthase, N-terminal; \"\r"]
["Q9NWU2","Glucose-induced degradation protein 8 homolog OS=Homo sapiens OX=9606 GN=GID8","GID8",26.748,3.945,5.3,1,1,1,0.913,0.864,0.704,1.127,1.318,1.064,1.414,0.0266,"cytoplasm\r",null,"GO:0043229 intracellular organelle; GO:0030054 cell junction; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR024964; IPR006595; IPR006594; IPR013144; ","\"CTLH/CRA C-terminal to LisH motif domain; CTLH, C-terminal LisH motif; LIS1 homology motif; CRA domain; \"\r"]
["Q9NX24","H/ACA ribonucleoprotein complex subunit 2 OS=Homo sapiens OX=9606 GN=NHP2","NHP2",17.201,3.1558,6.5,1,1,1,0.919,1.012,0.947,1.006,1.031,1.088,1.086,0.0875,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0022613 ribonucleoprotein complex biogenesis; GO:0006518 peptide metabolic process; GO:0009058 biosynthetic process; GO:0010833 telomere maintenance via telomere lengthening; GO:0009451 RNA modification; GO:0044237 cellular metabolic process; GO:0042273 ribosomal large subunit biogenesis; GO:0008152 metabolic process; GO:0032879 regulation of localization; GO:0006364 rRNA processing; GO:0000470 maturation of LSU-rRNA; GO:1904874 positive regulation of telomerase RNA localization to Cajal body; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0031118 rRNA pseudouridine synthesis; GO:0006412 translation; GO:0016072 rRNA metabolic process; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0018130 heterocycle biosynthetic process; GO:0043043 peptide biosynthetic process; GO:0042254 ribosome biogenesis; GO:1901360 organic cyclic compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0016070 RNA metabolic process; GO:0040031 snRNA modification; GO:0050789 regulation of biological process; GO:0000469 cleavage involved in rRNA processing; GO:0090304 nucleic acid metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0032200 telomere organization; GO:0090305 nucleic acid phosphodiester bond hydrolysis; GO:1901362 organic cyclic compound biosynthetic process; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0006259 DNA metabolic process; GO:0000154 rRNA modification; GO:0044267 cellular protein metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0060249 anatomical structure homeostasis; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0016073 snRNA metabolic process; GO:0071897 DNA biosynthetic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:1904872 regulation of telomerase RNA localization to Cajal body; GO:0001522 pseudouridine synthesis; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:0007004 telomere maintenance via telomerase; GO:1901576 organic substance biosynthetic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0090501 RNA phosphodiester bond hydrolysis; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0051276 chromosome organization; GO:0006996 organelle organization; GO:0031120 snRNA pseudouridine synthesis; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0043412 macromolecule modification; GO:0034660 ncRNA metabolic process; GO:0006278 RNA-dependent DNA biosynthetic process; GO:1901564 organonitrogen compound metabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:0000723 telomere maintenance; ","GO:0000784 nuclear chromosome, telomeric region; GO:0000781 chromosome, telomeric region; GO:0031429 box H/ACA snoRNP complex; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0015030 Cajal body; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0044454 nuclear chromosome part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0072588 box H/ACA RNP complex; GO:0043227 membrane-bounded organelle; GO:0005697 telomerase holoenzyme complex; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044452 nucleolar part; GO:0005730 nucleolus; GO:0043226 organelle; GO:0098687 chromosomal region; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0072589 box H/ACA scaRNP complex; GO:0005732 small nucleolar ribonucleoprotein complex; GO:0090661 box H/ACA telomerase RNP complex; GO:0000228 nuclear chromosome; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0044428 nuclear part; ","GO:0030515 snoRNA binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0034513 box H/ACA snoRNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0070034 telomerase RNA binding; ","K11129","NHP2; H/ACA ribonucleoprotein complex subunit 2","hsa03008 Ribosome biogenesis in eukaryotes - Homo sapiens (human); ","IPR029064; IPR004038; ","50S ribosomal protein L30e-like; Ribosomal protein L7Ae/L30e/S12e/Gadd45; \r"]
["Q9NX46","Poly(ADP-ribose) glycohydrolase ARH3 OS=Homo sapiens OX=9606 GN=ADPRHL2","ADPRHL2",38.946,23.551,17.1,5,9,5,0.897,1.013,1.011,0.995,0.963,1.078,1.039,0.497,"nucleus\r","GO:0033554 cellular response to stress; GO:0051716 cellular response to stimulus; GO:0000303 response to superoxide; GO:0034614 cellular response to reactive oxygen species; GO:0006950 response to stress; GO:0071451 cellular response to superoxide; GO:0071450 cellular response to oxygen radical; GO:0000302 response to reactive oxygen species; GO:1901700 response to oxygen-containing compound; GO:0050896 response to stimulus; GO:1901701 cellular response to oxygen-containing compound; GO:0042221 response to chemical; GO:0006979 response to oxidative stress; GO:0000305 response to oxygen radical; GO:0010035 response to inorganic substance; GO:0034599 cellular response to oxidative stress; GO:0009987 cellular process; GO:0070887 cellular response to chemical stimulus; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0016798 hydrolase activity, acting on glycosyl bonds; GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds; GO:0004649 poly(ADP-ribose) glycohydrolase activity; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0016787 hydrolase activity; ","K11687"]
["Q9NX63","MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3","CHCHD3",26.152,27.995,28.2,7,10,7,1.049,1.055,0.96,0.965,0.939,1.006,0.95,0.235,"extracellular\r","GO:0097659 nucleic acid-templated transcription; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0051253 negative regulation of RNA metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0007005 mitochondrion organization; GO:0043170 macromolecule metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0044801 single-organism membrane fusion; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0000122 negative regulation of transcription from RNA polymerase II promoter; GO:0044763 single-organism cellular process; GO:0061025 membrane fusion; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0016070 RNA metabolic process; GO:0007007 inner mitochondrial membrane organization; GO:1902589 single-organism organelle organization; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:1902679 negative regulation of RNA biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0042407 cristae formation; GO:0007006 mitochondrial membrane organization; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0071704 organic substance metabolic process; GO:0045892 negative regulation of transcription, DNA-templated; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0008053 mitochondrial fusion; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0044802 single-organism membrane organization; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0006807 nitrogen compound metabolic process; GO:0048284 organelle fusion; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0044238 primary metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0009890 negative regulation of biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0010467 gene expression; GO:0031327 negative regulation of cellular biosynthetic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0031305 integral component of mitochondrial inner membrane; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0031304 intrinsic component of mitochondrial inner membrane; GO:0044422 organelle part; GO:0061617 MICOS complex; GO:0070062 extracellular exosome; GO:0005740 mitochondrial envelope; GO:0031301 integral component of organelle membrane; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0043229 intracellular organelle; GO:0098573 intrinsic component of mitochondrial membrane; GO:0044429 mitochondrial part; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0031975 envelope; GO:0032592 integral component of mitochondrial membrane; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0031966 mitochondrial membrane; GO:0031300 intrinsic component of organelle membrane; GO:0044444 cytoplasmic part; ","GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding; GO:0032947 protein complex scaffold; GO:0005488 binding; GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding; GO:0001071 nucleic acid binding transcription factor activity; GO:0005515 protein binding; GO:0019902 phosphatase binding; GO:0005198 structural molecule activity; GO:0019899 enzyme binding; GO:0003700 transcription factor activity, sequence-specific DNA binding; ","K17563"]
["Q9NX76","CKLF-like MARVEL transmembrane domain-containing protein 6 OS=Homo sapiens OX=9606 GN=CMTM6","CMTM6",20.419,2.3692,5.5,1,1,1,0.986,0.876,1.054,1.134,1.009,0.946,1.059,0.489,"plasma membrane\r","GO:0045321 leukocyte activation; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0051234 establishment of localization; GO:0009605 response to external stimulus; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0002274 myeloid leukocyte activation; GO:0002443 leukocyte mediated immunity; GO:0016192 vesicle-mediated transport; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0002376 immune system process; GO:0043312 neutrophil degranulation; GO:0006935 chemotaxis; GO:0002263 cell activation involved in immune response; GO:0002444 myeloid leukocyte mediated immunity; GO:0002366 leukocyte activation involved in immune response; GO:0006810 transport; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0042221 response to chemical; GO:0032940 secretion by cell; GO:0001775 cell activation; GO:0042330 taxis; GO:0040011 locomotion; GO:0043299 leukocyte degranulation; GO:0006955 immune response; GO:0051179 localization; GO:0006887 exocytosis; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005765 lysosomal membrane; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0035579 specific granule membrane; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0035577 azurophil granule membrane; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0098852 lytic vacuole membrane; GO:0042582 azurophil granule; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0030667 secretory granule membrane; GO:0005766 primary lysosome; GO:0042581 specific granule; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005125 cytokine activity; GO:0005515 protein binding; GO:0005102 receptor binding; GO:0005488 binding; ",{"$nulls":3},"IPR008253; ","Marvel domain; \r"]
["Q9NXV6","CDKN2A-interacting protein OS=Homo sapiens OX=9606 GN=CDKN2AIP","CDKN2AIP",61.124,4.8838,3.3,2,2,2,0.984,0.913,0.861,1.078,1.111,1.054,1.176,0.0171,"nucleus\r","GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0051716 cellular response to stimulus; GO:0045926 negative regulation of growth; GO:0065008 regulation of biological quality; GO:0040008 regulation of growth; GO:0006950 response to stress; GO:0030307 positive regulation of cell growth; GO:0023051 regulation of signaling; GO:0048522 positive regulation of cellular process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0048518 positive regulation of biological process; GO:0006974 cellular response to DNA damage stimulus; GO:0045927 positive regulation of growth; GO:0001558 regulation of cell growth; GO:0030308 negative regulation of cell growth; GO:0010646 regulation of cell communication; GO:0050789 regulation of biological process; GO:0023056 positive regulation of signaling; GO:0048583 regulation of response to stimulus; GO:0009967 positive regulation of signal transduction; GO:0010647 positive regulation of cell communication; GO:0051128 regulation of cellular component organization; GO:0031647 regulation of protein stability; GO:0048584 positive regulation of response to stimulus; GO:0009987 cellular process; GO:0009966 regulation of signal transduction; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044452 nucleolar part; GO:0044424 intracellular part; GO:0005730 nucleolus; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0001652 granular component; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005515 protein binding; GO:0002039 p53 binding; GO:0005488 binding; GO:0003676 nucleic acid binding; ",{"$nulls":3},"IPR021859; IPR014720; ","\"XRN-Two Binding Domain, XTBD; Double-stranded RNA-binding domain; \"\r"]
["Q9NY12","H/ACA ribonucleoprotein complex subunit 1 OS=Homo sapiens OX=9606 GN=GAR1","GAR1",22.348,15.608,8.3,1,1,1,0.788,1.024,0.852,1.014,1.187,1.127,1.249,0.0664,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0016043 cellular component organization; GO:0065008 regulation of biological quality; GO:0022613 ribonucleoprotein complex biogenesis; GO:0034220 ion transmembrane transport; GO:0006725 cellular aromatic compound metabolic process; GO:0006259 DNA metabolic process; GO:0000154 rRNA modification; GO:0009058 biosynthetic process; GO:0010833 telomere maintenance via telomere lengthening; GO:0044237 cellular metabolic process; GO:0009451 RNA modification; GO:0060249 anatomical structure homeostasis; GO:0071704 organic substance metabolic process; GO:0051234 establishment of localization; GO:0042592 homeostatic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0006812 cation transport; GO:0006364 rRNA processing; GO:0071897 DNA biosynthetic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0031118 rRNA pseudouridine synthesis; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0034470 ncRNA processing; GO:0006396 RNA processing; GO:0016072 rRNA metabolic process; GO:0018130 heterocycle biosynthetic process; GO:0098655 cation transmembrane transport; GO:0001522 pseudouridine synthesis; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0042254 ribosome biogenesis; GO:0007004 telomere maintenance via telomerase; GO:0044238 primary metabolic process; GO:0016074 snoRNA metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0000454 snoRNA guided rRNA pseudouridine synthesis; GO:0006810 transport; GO:0016070 RNA metabolic process; GO:0055085 transmembrane transport; GO:0051276 chromosome organization; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0090304 nucleic acid metabolic process; GO:0006996 organelle organization; GO:0006811 ion transport; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0032200 telomere organization; GO:0051179 localization; GO:0043412 macromolecule modification; GO:0034660 ncRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0006278 RNA-dependent DNA biosynthetic process; GO:0000723 telomere maintenance; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0000784 nuclear chromosome, telomeric region; GO:0000781 chromosome, telomeric region; GO:0031429 box H/ACA snoRNP complex; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0015030 Cajal body; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0044454 nuclear chromosome part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0072588 box H/ACA RNP complex; GO:0043227 membrane-bounded organelle; GO:0005697 telomerase holoenzyme complex; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044452 nucleolar part; GO:0005730 nucleolus; GO:0001650 fibrillar center; GO:0043226 organelle; GO:0098687 chromosomal region; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0072589 box H/ACA scaRNP complex; GO:0005732 small nucleolar ribonucleoprotein complex; GO:0090661 box H/ACA telomerase RNP complex; GO:0000228 nuclear chromosome; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0044428 nuclear part; ","GO:0003723 RNA binding; GO:0015075 ion transmembrane transporter activity; GO:0022803 passive transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0015267 channel activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0070034 telomerase RNA binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0030515 snoRNA binding; GO:0022838 substrate-specific channel activity; GO:0034513 box H/ACA snoRNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005261 cation channel activity; GO:0005216 ion channel activity; GO:0008324 cation transmembrane transporter activity; GO:0022857 transmembrane transporter activity; GO:0005215 transporter activity; ","K11128","GAR1; H/ACA ribonucleoprotein complex subunit 1","hsa03008 Ribosome biogenesis in eukaryotes - Homo sapiens (human); ","IPR009000; ","\"Translation protein, beta-barrel domain; \"\r"]
["Q9NY27","Serine/threonine-protein phosphatase 4 regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PPP4R2","PPP4R2",46.898,4.1285,4.3,2,2,2,0.919,1.012,0.909,1.029,1.067,1.065,1.113,0.0401,"nucleus\r","GO:0050794 regulation of cellular process; GO:0006725 cellular aromatic compound metabolic process; GO:2001020 regulation of response to DNA damage stimulus; GO:0010569 regulation of double-strand break repair via homologous recombination; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0080134 regulation of response to stress; GO:0044237 cellular metabolic process; GO:0006282 regulation of DNA repair; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0008380 RNA splicing; GO:0000018 regulation of DNA recombination; GO:0009987 cellular process; GO:0006396 RNA processing; GO:0080090 regulation of primary metabolic process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0044238 primary metabolic process; GO:0031323 regulation of cellular metabolic process; GO:2000779 regulation of double-strand break repair; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:0050789 regulation of biological process; GO:0080135 regulation of cellular response to stress; GO:0051052 regulation of DNA metabolic process; GO:0090304 nucleic acid metabolic process; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0006464 cellular protein modification process; GO:0010467 gene expression; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:0016071 mRNA metabolic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0008287 protein serine/threonine phosphatase complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:1903293 phosphatase complex; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0005856 cytoskeleton; GO:0043231 intracellular membrane-bounded organelle; GO:1902494 catalytic complex; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0005815 microtubule organizing center; GO:0070013 intracellular organelle lumen; GO:0030289 protein phosphatase 4 complex; GO:0015630 microtubule cytoskeleton; GO:0005813 centrosome; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0030674 protein binding, bridging; GO:0030234 enzyme regulator activity; GO:0019888 protein phosphatase regulator activity; GO:0019208 phosphatase regulator activity; GO:0005488 binding; GO:0060090 binding, bridging; GO:0005515 protein binding; GO:0098772 molecular function regulator; ","K15425"]
["Q9NYK5","39S ribosomal protein L39, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL39","MRPL39",38.711,3.5663,5,2,2,2,0.81,0.844,0.896,1.236,1.077,1.129,1.35,0.0039,"mitochondria\r","GO:0016043 cellular component organization; GO:0006518 peptide metabolic process; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:0043241 protein complex disassembly; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0043624 cellular protein complex disassembly; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006412 translation; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0071822 protein complex subunit organization; GO:0006414 translational elongation; GO:0043043 peptide biosynthetic process; GO:0044763 single-organism cellular process; GO:0032984 macromolecular complex disassembly; GO:0006807 nitrogen compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0032543 mitochondrial translation; GO:0070126 mitochondrial translational termination; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0006415 translational termination; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0070125 mitochondrial translational elongation; GO:0044260 cellular macromolecule metabolic process; GO:0022411 cellular component disassembly; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0071840 cellular component organization or biogenesis; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005762 mitochondrial large ribosomal subunit; GO:0005623 cell; GO:0000313 organellar ribosome; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044391 ribosomal subunit; GO:0005622 intracellular; GO:0044464 cell part; GO:0019866 organelle inner membrane; GO:0000315 organellar large ribosomal subunit; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005840 ribosome; GO:0005759 mitochondrial matrix; GO:0044429 mitochondrial part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005761 mitochondrial ribosome; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0015934 large ribosomal subunit; GO:0031975 envelope; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:1901265 nucleoside phosphate binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0000166 nucleotide binding; GO:0036094 small molecule binding; ","K17420",null,null,"IPR018163; IPR012676; IPR012675; ","\"Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain; TGS-like; Beta-grasp domain; \"\r"]
["Q9NYM9","BET1-like protein OS=Homo sapiens OX=9606 GN=BET1L","BET1L",12.388,6.2185,13.5,1,1,1,1.027,1.106,0.792,1.103,0.984,1.005,1.057,0.581,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0060627 regulation of vesicle-mediated transport; GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0051049 regulation of transport; GO:0016192 vesicle-mediated transport; GO:0048193 Golgi vesicle transport; GO:0061025 membrane fusion; GO:0071702 organic substance transport; GO:0015031 protein transport; GO:0051641 cellular localization; GO:0051234 establishment of localization; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:0016197 endosomal transport; GO:0050789 regulation of biological process; GO:0051649 establishment of localization in cell; GO:0042147 retrograde transport, endosome to Golgi; GO:0032879 regulation of localization; GO:0061024 membrane organization; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0051179 localization; GO:0016482 cytosolic transport; GO:0006888 ER to Golgi vesicle-mediated transport; GO:2000156 regulation of retrograde vesicle-mediated transport, Golgi to ER; GO:0009987 cellular process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0098588 bounding membrane of organelle; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0031224 intrinsic component of membrane; GO:0032991 macromolecular complex; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0044431 Golgi apparatus part; GO:0005768 endosome; GO:0043234 protein complex; GO:0005794 Golgi apparatus; GO:0043227 membrane-bounded organelle; GO:0031201 SNARE complex; GO:0044444 cytoplasmic part; ","GO:0005484 SNAP receptor activity; GO:0005515 protein binding; GO:0005488 binding; ","K08504","BET1; blocked early in transport 1","hsa04130 SNARE interactions in vesicular transport - Homo sapiens (human); ","IPR000727; ","Target SNARE coiled-coil homology domain; \r"]
["Q9NYZ1","Golgi apparatus membrane protein TVP23 homolog B OS=Homo sapiens OX=9606 GN=TVP23B","TVP23B",23.576,2.0977,3.9,1,2,1,0.757,0.983,0.852,1.12,1.14,1.14,1.312,0.0673,"plasma membrane\r","GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0071702 organic substance transport; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:1902578 single-organism localization; GO:0032940 secretion by cell; GO:0009306 protein secretion; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0051179 localization; GO:0009987 cellular process; GO:0046903 secretion; GO:0044765 single-organism transport; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0098588 bounding membrane of organelle; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0030173 integral component of Golgi membrane; GO:0005623 cell; GO:0031228 intrinsic component of Golgi membrane; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031301 integral component of organelle membrane; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044431 Golgi apparatus part; GO:0043227 membrane-bounded organelle; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; GO:0031300 intrinsic component of organelle membrane; "]
["Q9NZ32","Actin-related protein 10 OS=Homo sapiens OX=9606 GN=ACTR10","ACTR10",46.306,14.475,8.4,3,3,3,0.955,0.812,0.963,1.054,1.022,1.187,1.195,0.0671,"cytoplasm\r","GO:0045321 leukocyte activation; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0051234 establishment of localization; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0002443 leukocyte mediated immunity; GO:0016192 vesicle-mediated transport; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0002376 immune system process; GO:0043312 neutrophil degranulation; GO:0007017 microtubule-based process; GO:0002263 cell activation involved in immune response; GO:0002444 myeloid leukocyte mediated immunity; GO:0002366 leukocyte activation involved in immune response; GO:0006810 transport; GO:0007018 microtubule-based movement; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0032940 secretion by cell; GO:0006928 movement of cell or subcellular component; GO:0001775 cell activation; GO:0043299 leukocyte degranulation; GO:0051179 localization; GO:0006955 immune response; GO:0006887 exocytosis; ","GO:0034774 secretory granule lumen; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0005869 dynactin complex; GO:0044424 intracellular part; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0043228 non-membrane-bounded organelle; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005875 microtubule associated complex; GO:0005576 extracellular region; GO:0015629 actin cytoskeleton; GO:0042582 azurophil granule; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ","K16576"]
["Q9NZD2","Glycolipid transfer protein OS=Homo sapiens OX=9606 GN=GLTP","GLTP",23.85,30.993,33.5,6,9,6,0.832,0.774,0.756,1.208,1.271,1.168,1.544,0.000324,"cytoplasm\r","GO:1903509 liposaccharide metabolic process; GO:0006869 lipid transport; GO:0046836 glycolipid transport; GO:0006643 membrane lipid metabolic process; GO:0006687 glycosphingolipid metabolic process; GO:0006664 glycolipid metabolic process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0010876 lipid localization; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0051234 establishment of localization; GO:0006810 transport; GO:0008152 metabolic process; GO:1902578 single-organism localization; GO:0044710 single-organism metabolic process; GO:1901264 carbohydrate derivative transport; GO:1901135 carbohydrate derivative metabolic process; GO:0006665 sphingolipid metabolic process; GO:0051179 localization; GO:0033036 macromolecule localization; GO:0009987 cellular process; GO:0006629 lipid metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0044765 single-organism transport; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901505 carbohydrate derivative transporter activity; GO:0051861 glycolipid binding; GO:0097367 carbohydrate derivative binding; GO:0005488 binding; GO:0008289 lipid binding; GO:0005319 lipid transporter activity; GO:0017089 glycolipid transporter activity; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0005215 transporter activity; ",{"$nulls":3},"IPR014830; ","Glycolipid transfer protein domain; \r"]
["Q9NZH8","Interleukin-36 gamma OS=Homo sapiens OX=9606 GN=IL36G","IL36G",18.721,51.202,66.3,8,12,8,0.558,0.618,0.566,1.311,1.361,1.398,2.336,2.06e-05,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0051716 cellular response to stimulus; GO:0034097 response to cytokine; GO:0006950 response to stress; GO:0007166 cell surface receptor signaling pathway; GO:0071310 cellular response to organic substance; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0050896 response to stimulus; GO:0023052 signaling; GO:0071345 cellular response to cytokine stimulus; GO:0045087 innate immune response; GO:0007165 signal transduction; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0007154 cell communication; GO:0007267 cell-cell signaling; GO:0006954 inflammatory response; GO:0006952 defense response; GO:0006955 immune response; GO:0019221 cytokine-mediated signaling pathway; GO:0009987 cellular process; GO:0070887 cellular response to chemical stimulus; GO:0065007 biological regulation; ","GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005576 extracellular region; ","GO:0005125 cytokine activity; GO:0005102 receptor binding; GO:0005488 binding; GO:0005149 interleukin-1 receptor binding; GO:0005126 cytokine receptor binding; GO:0070851 growth factor receptor binding; GO:0005515 protein binding; ","K05487"]
["Q9NZJ7","Mitochondrial carrier homolog 1 OS=Homo sapiens OX=9606 GN=MTCH1","MTCH1",41.544,3.661,8,2,2,2,0.944,1.065,0.999,0.978,1.022,1,0.997,0.967,"plasma membrane\r","GO:0021700 developmental maturation; GO:0010941 regulation of cell death; GO:0032270 positive regulation of cellular protein metabolic process; GO:0023051 regulation of signaling; GO:0048869 cellular developmental process; GO:0048666 neuron development; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0045161 neuronal ion channel clustering; GO:0051234 establishment of localization; GO:0010646 regulation of cell communication; GO:0009893 positive regulation of metabolic process; GO:0044093 positive regulation of molecular function; GO:0006915 apoptotic process; GO:0048469 cell maturation; GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0052548 regulation of endopeptidase activity; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0010950 positive regulation of endopeptidase activity; GO:0080090 regulation of primary metabolic process; GO:2000116 regulation of cysteine-type endopeptidase activity; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0010942 positive regulation of cell death; GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0006810 transport; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0052547 regulation of peptidase activity; GO:0048856 anatomical structure development; GO:0042551 neuron maturation; GO:0010952 positive regulation of peptidase activity; GO:0043068 positive regulation of programmed cell death; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:2001056 positive regulation of cysteine-type endopeptidase activity; GO:0060255 regulation of macromolecule metabolic process; GO:0043067 regulation of programmed cell death; GO:0043065 positive regulation of apoptotic process; GO:0048468 cell development; GO:0030154 cell differentiation; GO:0045862 positive regulation of proteolysis; GO:0051345 positive regulation of hydrolase activity; GO:0007275 multicellular organism development; GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:0048731 system development; GO:0044802 single-organism membrane organization; GO:0030162 regulation of proteolysis; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0030182 neuron differentiation; GO:0051247 positive regulation of protein metabolic process; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0061024 membrane organization; GO:0012501 programmed cell death; GO:0051179 localization; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044429 mitochondrial part; GO:0031090 organelle membrane; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005740 mitochondrial envelope; GO:0044464 cell part; GO:0005622 intracellular; GO:0044425 membrane part; GO:0031975 envelope; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ","K17885",null,null,"IPR023395; ","Mitochondrial carrier domain; \r"]
["Q9NZL9","Methionine adenosyltransferase 2 subunit beta OS=Homo sapiens OX=9606 GN=MAT2B","MAT2B",37.551,69.882,30.2,9,14,9,0.959,0.919,0.94,1.061,1.064,1.058,1.13,0.0102,"cytoplasm\r","GO:0051188 cofactor biosynthetic process; GO:0006790 sulfur compound metabolic process; GO:0046500 S-adenosylmethionine metabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0006732 coenzyme metabolic process; GO:0009058 biosynthetic process; GO:1901576 organic substance biosynthetic process; GO:0044237 cellular metabolic process; GO:0044249 cellular biosynthetic process; GO:0044272 sulfur compound biosynthetic process; GO:0032259 methylation; GO:0051186 cofactor metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0006730 one-carbon metabolic process; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0065009 regulation of molecular function; GO:0009108 coenzyme biosynthetic process; GO:0009987 cellular process; GO:0006556 S-adenosylmethionine biosynthetic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:1990234 transferase complex; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:1902494 catalytic complex; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0048269 methionine adenosyltransferase complex; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0030234 enzyme regulator activity; GO:0019899 enzyme binding; GO:0048270 methionine adenosyltransferase regulator activity; GO:0005488 binding; ","K00789","metK; S-adenosylmethionine synthetase [EC:2.5.1.6]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00270 Cysteine and methionine metabolism - Homo sapiens (human); hsa01230 Biosynthesis of amino acids - Homo sapiens (human); ","IPR029903; IPR016040; ","RmlD-like substrate binding domain; NAD(P)-binding domain; \r"]
["Q9NZN4","EH domain-containing protein 2 OS=Homo sapiens OX=9606 GN=EHD2","EHD2",61.161,242.35,64.1,28,73,24,1.117,1.098,1.11,0.879,0.906,0.892,0.805,2.38e-05,"cytoplasm\r","GO:0060627 regulation of vesicle-mediated transport; GO:0010256 endomembrane system organization; GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0060142 regulation of syncytium formation by plasma membrane fusion; GO:0044699 single-organism process; GO:1901741 positive regulation of myoblast fusion; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0009611 response to wounding; GO:0030036 actin cytoskeleton organization; GO:0032879 regulation of localization; GO:0010830 regulation of myotube differentiation; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0051147 regulation of muscle cell differentiation; GO:0072657 protein localization to membrane; GO:0030866 cortical actin cytoskeleton organization; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0007009 plasma membrane organization; GO:2001135 regulation of endocytic recycling; GO:0032501 multicellular organismal process; GO:0051050 positive regulation of transport; GO:0016197 endosomal transport; GO:0006810 transport; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0051149 positive regulation of muscle cell differentiation; GO:0050817 coagulation; GO:0051094 positive regulation of developmental process; GO:0097320 plasma membrane tubulation; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0051155 positive regulation of striated muscle cell differentiation; GO:0050896 response to stimulus; GO:0060143 positive regulation of syncytium formation by plasma membrane fusion; GO:0030865 cortical cytoskeleton organization; GO:0007599 hemostasis; GO:0045597 positive regulation of cell differentiation; GO:1990778 protein localization to cell periphery; GO:2001137 positive regulation of endocytic recycling; GO:1902578 single-organism localization; GO:1902580 single-organism cellular localization; GO:0034613 cellular protein localization; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0050878 regulation of body fluid levels; GO:0006950 response to stress; GO:0051049 regulation of transport; GO:0010831 positive regulation of myotube differentiation; GO:1901739 regulation of myoblast fusion; GO:0016192 vesicle-mediated transport; GO:0044802 single-organism membrane organization; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0051153 regulation of striated muscle cell differentiation; GO:0051641 cellular localization; GO:0072659 protein localization to plasma membrane; GO:0070727 cellular macromolecule localization; GO:0042060 wound healing; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0022603 regulation of anatomical structure morphogenesis; GO:0030029 actin filament-based process; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0032456 endocytic recycling; GO:0050793 regulation of developmental process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0019898 extrinsic component of membrane; GO:0098857 membrane microdomain; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0055038 recycling endosome membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0055037 recycling endosome; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0098590 plasma membrane region; GO:0015630 microtubule cytoskeleton; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0098589 membrane region; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0005768 endosome; GO:0045121 membrane raft; GO:0043227 membrane-bounded organelle; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0010008 endosome membrane; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0005901 caveola; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0044853 plasma membrane raft; GO:0045171 intercellular bridge; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003676 nucleic acid binding; GO:0046872 metal ion binding; GO:0032555 purine ribonucleotide binding; GO:0019904 protein domain specific binding; GO:0001883 purine nucleoside binding; GO:0032561 guanyl ribonucleotide binding; GO:0005509 calcium ion binding; GO:0036094 small molecule binding; ","K12469","EHD2; EH domain-containing protein 2","hsa04144 Endocytosis - Homo sapiens (human); ","IPR030381; IPR000261; IPR011992; IPR002048; IPR027417; IPR031692; ","\"Dynamin-type guanine nucleotide-binding (G) domain; EH domain; EF-hand domain pair; EF-hand domain; P-loop containing nucleoside triphosphate hydrolase; EH domain-containing protein, N-terminal; \"\r"]
["Q9NZT2","Opioid growth factor receptor OS=Homo sapiens OX=9606 GN=OGFR","OGFR",73.324,20.876,9.6,5,5,5,0.957,0.915,1.029,1.061,1.098,0.991,1.086,0.144,"nucleus\r","GO:0044700 single organism signaling; GO:0050794 regulation of cellular process; GO:0051716 cellular response to stimulus; GO:0040008 regulation of growth; GO:0044699 single-organism process; GO:0023052 signaling; GO:0050896 response to stimulus; GO:0001558 regulation of cell growth; GO:0007186 G-protein coupled receptor signaling pathway; GO:0007165 signal transduction; GO:0050789 regulation of biological process; GO:0007154 cell communication; GO:0051128 regulation of cellular component organization; GO:0038003 opioid receptor signaling pathway; GO:0009987 cellular process; GO:0065007 biological regulation; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; ","GO:0038023 signaling receptor activity; GO:0008528 G-protein coupled peptide receptor activity; GO:0004985 opioid receptor activity; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0005488 binding; GO:0004930 G-protein coupled receptor activity; GO:0005515 protein binding; GO:0001653 peptide receptor activity; GO:0004888 transmembrane signaling receptor activity; GO:0004871 signal transducer activity; GO:0099600 transmembrane receptor activity; ",{"$nulls":3},"IPR006757; ","Opioid growth factor receptor (OGFr) conserved domain; \r"]
["Q9NZW5","MAGUK p55 subfamily member 6 OS=Homo sapiens OX=9606 GN=MPP6","MPP6",61.116,3.5234,2.2,1,1,1,1.149,1.005,1.107,1.018,0.863,0.881,0.847,0.0631,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0016043 cellular component organization; GO:0071822 protein complex subunit organization; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0070271 protein complex biogenesis; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0043933 macromolecular complex subunit organization; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0071944 cell periphery; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; GO:0005886 plasma membrane; ","GO:0019904 protein domain specific binding; GO:0005515 protein binding; GO:0030165 PDZ domain binding; GO:0005488 binding; ",{"$nulls":3},"IPR014775; IPR011511; IPR001452; IPR008144; IPR027417; IPR008145; IPR001478; IPR004172; ","\"L27 domain, C-terminal; Variant SH3 domain; SH3 domain; Guanylate kinase-like domain; P-loop containing nucleoside triphosphate hydrolase; Guanylate kinase/L-type calcium channel beta subunit; PDZ domain; L27 domain; \"\r"]
["Q9P016","Thymocyte nuclear protein 1 OS=Homo sapiens OX=9606 GN=THYN1","THYN1",25.697,11.746,17.8,4,4,4,1.024,0.933,0.876,1.062,1.072,1.037,1.119,0.0689,"nucleus\r",null,"GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; ",{"$nulls":4},"IPR015947; IPR002740; ","PUA-like domain; EVE domain; \r"]
["Q9P0J0","NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 OS=Homo sapiens OX=9606 GN=NDUFA13","NDUFA13",16.698,24.359,23.6,4,6,4,1,1.033,0.963,0.985,1.044,0.984,1.006,0.85,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0009116 nucleoside metabolic process; GO:0032270 positive regulation of cellular protein metabolic process; GO:0044237 cellular metabolic process; GO:0071345 cellular response to cytokine stimulus; GO:0015031 protein transport; GO:0045039 protein import into mitochondrial inner membrane; GO:0001558 regulation of cell growth; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0065003 macromolecular complex assembly; GO:0044093 positive regulation of molecular function; GO:0019693 ribose phosphate metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0033365 protein localization to organelle; GO:0008104 protein localization; GO:0044765 single-organism transport; GO:0052548 regulation of endopeptidase activity; GO:0051716 cellular response to stimulus; GO:0010950 positive regulation of endopeptidase activity; GO:0072657 protein localization to membrane; GO:0010257 NADH dehydrogenase complex assembly; GO:0080090 regulation of primary metabolic process; GO:0009894 regulation of catabolic process; GO:0044281 small molecule metabolic process; GO:0071806 protein transmembrane transport; GO:0044763 single-organism cellular process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0071396 cellular response to lipid; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0006810 transport; GO:0007007 inner mitochondrial membrane organization; GO:1903506 regulation of nucleic acid-templated transcription; GO:1902532 negative regulation of intracellular signal transduction; GO:0051336 regulation of hydrolase activity; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0032526 response to retinoic acid; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:0010604 positive regulation of macromolecule metabolic process; GO:0022900 electron transport chain; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0009126 purine nucleoside monophosphate metabolic process; GO:0060548 negative regulation of cell death; GO:0072655 establishment of protein localization to mitochondrion; GO:0010952 positive regulation of peptidase activity; GO:0043068 positive regulation of programmed cell death; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0035456 response to interferon-beta; GO:0046907 intracellular transport; GO:0016310 phosphorylation; GO:0097190 apoptotic signaling pathway; GO:2001056 positive regulation of cysteine-type endopeptidase activity; GO:0007006 mitochondrial membrane organization; GO:0009259 ribonucleotide metabolic process; GO:1901700 response to oxygen-containing compound; GO:0043067 regulation of programmed cell death; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0032981 mitochondrial respiratory chain complex I assembly; GO:0045892 negative regulation of transcription, DNA-templated; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0071229 cellular response to acid chemical; GO:0051345 positive regulation of hydrolase activity; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0009896 positive regulation of catabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0006626 protein targeting to mitochondrion; GO:1901135 carbohydrate derivative metabolic process; GO:1902580 single-organism cellular localization; GO:0042176 regulation of protein catabolic process; GO:0034613 cellular protein localization; GO:0009966 regulation of signal transduction; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0090150 establishment of protein localization to membrane; GO:0009119 ribonucleoside metabolic process; GO:0006461 protein complex assembly; GO:1902531 regulation of intracellular signal transduction; GO:0071702 organic substance transport; GO:0009141 nucleoside triphosphate metabolic process; GO:0030162 regulation of proteolysis; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0006163 purine nucleotide metabolic process; GO:0045184 establishment of protein localization; GO:0055085 transmembrane transport; GO:0009890 negative regulation of biosynthetic process; GO:0051247 positive regulation of protein metabolic process; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0061024 membrane organization; GO:0019637 organophosphate metabolic process; GO:0012501 programmed cell death; GO:0051179 localization; GO:1901564 organonitrogen compound metabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:0001101 response to acid chemical; GO:0042278 purine nucleoside metabolic process; GO:0072594 establishment of protein localization to organelle; GO:0009968 negative regulation of signal transduction; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0017038 protein import; GO:0023051 regulation of signaling; GO:0009117 nucleotide metabolic process; GO:0006839 mitochondrial transport; GO:0044699 single-organism process; GO:0035458 cellular response to interferon-beta; GO:0051253 negative regulation of RNA metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:2001233 regulation of apoptotic signaling pathway; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0051649 establishment of localization in cell; GO:2001243 negative regulation of intrinsic apoptotic signaling pathway; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0009893 positive regulation of metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0006915 apoptotic process; GO:0007005 mitochondrion organization; GO:0071300 cellular response to retinoic acid; GO:0065002 intracellular protein transmembrane transport; GO:0044743 protein transmembrane import into intracellular organelle; GO:0033036 macromolecule localization; GO:0070887 cellular response to chemical stimulus; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0045926 negative regulation of growth; GO:0010468 regulation of gene expression; GO:0071822 protein complex subunit organization; GO:0031326 regulation of cellular biosynthetic process; GO:0034097 response to cytokine; GO:2000116 regulation of cysteine-type endopeptidase activity; GO:0055114 oxidation-reduction process; GO:0006119 oxidative phosphorylation; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0006120 mitochondrial electron transport, NADH to ubiquinone; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:1902582 single-organism intracellular transport; GO:0010942 positive regulation of cell death; GO:0030308 negative regulation of cell growth; GO:1902589 single-organism organelle organization; GO:0097031 mitochondrial respiratory chain complex I biogenesis; GO:0032268 regulation of cellular protein metabolic process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:1902679 negative regulation of RNA biosynthetic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0070271 protein complex biogenesis; GO:0052547 regulation of peptidase activity; GO:0033108 mitochondrial respiratory chain complex assembly; GO:0016043 cellular component organization; GO:0043069 negative regulation of programmed cell death; GO:0040008 regulation of growth; GO:0006725 cellular aromatic compound metabolic process; GO:0042773 ATP synthesis coupled electron transport; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0043065 positive regulation of apoptotic process; GO:0022904 respiratory electron transport chain; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0033993 response to lipid; GO:0045862 positive regulation of proteolysis; GO:0072593 reactive oxygen species metabolic process; GO:0043066 negative regulation of apoptotic process; GO:0090151 establishment of protein localization to mitochondrial membrane; GO:1990542 mitochondrial transmembrane transport; GO:0006886 intracellular protein transport; GO:0034641 cellular nitrogen compound metabolic process; GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0009987 cellular process; GO:0043623 cellular protein complex assembly; GO:0046034 ATP metabolic process; GO:0034622 cellular macromolecular complex assembly; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0006807 nitrogen compound metabolic process; GO:0044802 single-organism membrane organization; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0070585 protein localization to mitochondrion; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0045333 cellular respiration; GO:0043933 macromolecular complex subunit organization; GO:0043085 positive regulation of catalytic activity; GO:0051641 cellular localization; GO:0046128 purine ribonucleoside metabolic process; GO:0070727 cellular macromolecule localization; GO:1901701 cellular response to oxygen-containing compound; GO:0008219 cell death; GO:0051246 regulation of protein metabolic process; GO:2001242 regulation of intrinsic apoptotic signaling pathway; GO:0045732 positive regulation of protein catabolic process; GO:0051128 regulation of cellular component organization; GO:0031327 negative regulation of cellular biosynthetic process; GO:0009150 purine ribonucleotide metabolic process; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0045271 respiratory chain complex I; GO:0032991 macromolecular complex; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0005747 mitochondrial respiratory chain complex I; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0005740 mitochondrial envelope; GO:0005654 nucleoplasm; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0098803 respiratory chain complex; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0005739 mitochondrion; GO:0005746 mitochondrial respiratory chain; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0030964 NADH dehydrogenase complex; GO:1990204 oxidoreductase complex; GO:0031975 envelope; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0031966 mitochondrial membrane; GO:0070469 respiratory chain; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0050136 NADH dehydrogenase (quinone) activity; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; GO:0008137 NADH dehydrogenase (ubiquinone) activity; GO:0016491 oxidoreductase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0003954 NADH dehydrogenase activity; GO:0097367 carbohydrate derivative binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K11353","NDUFA13; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13","hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); "]
["Q9P0L0","Vesicle-associated membrane protein-associated protein A OS=Homo sapiens OX=9606 GN=VAPA","VAPA",27.893,31.59,32.9,8,13,7,1.018,1.008,0.916,1.05,0.964,1.054,1.043,0.397,"cytoplasm\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0044827 modulation by host of viral genome replication; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0008610 lipid biosynthetic process; GO:0008152 metabolic process; GO:0030148 sphingolipid biosynthetic process; GO:0070972 protein localization to endoplasmic reticulum; GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling; GO:0044789 modulation by host of viral release from host cell; GO:0044003 modification by symbiont of host morphology or physiology; GO:0033365 protein localization to organelle; GO:0044419 interspecies interaction between organisms; GO:0008104 protein localization; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0007399 nervous system development; GO:0044794 positive regulation by host of viral process; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0061025 membrane fusion; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0046907 intracellular transport; GO:0002283 neutrophil activation involved in immune response; GO:0044793 negative regulation by host of viral process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:1903901 negative regulation of viral life cycle; GO:0051817 modification of morphology or physiology of other organism involved in symbiotic interaction; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0051702 interaction with symbiont; GO:0007275 multicellular organism development; GO:0034613 cellular protein localization; GO:0009966 regulation of signal transduction; GO:1902531 regulation of intracellular signal transduction; GO:0044711 single-organism biosynthetic process; GO:0090114 COPII-coated vesicle budding; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0043900 regulation of multi-organism process; GO:1902188 positive regulation of viral release from host cell; GO:0002376 immune system process; GO:0045071 negative regulation of viral genome replication; GO:0044238 primary metabolic process; GO:0002263 cell activation involved in immune response; GO:1901576 organic substance biosynthetic process; GO:1902186 regulation of viral release from host cell; GO:0030182 neuron differentiation; GO:0045055 regulated exocytosis; GO:0006996 organelle organization; GO:0006900 membrane budding; GO:0061024 membrane organization; GO:0001775 cell activation; GO:0048584 positive regulation of response to stimulus; GO:0006955 immune response; GO:0051179 localization; GO:0006887 exocytosis; GO:1901564 organonitrogen compound metabolic process; GO:0040017 positive regulation of locomotion; GO:0006643 membrane lipid metabolic process; GO:0023051 regulation of signaling; GO:0048869 cellular developmental process; GO:0048666 neuron development; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0035821 modification of morphology or physiology of other organism; GO:0051234 establishment of localization; GO:0044068 modulation by symbiont of host cellular process; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0006665 sphingolipid metabolic process; GO:0033036 macromolecule localization; GO:0006629 lipid metabolic process; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:0048525 negative regulation of viral process; GO:1903902 positive regulation of viral life cycle; GO:0043902 positive regulation of multi-organism process; GO:0002446 neutrophil mediated immunity; GO:0048522 positive regulation of cellular process; GO:0045069 regulation of viral genome replication; GO:0023052 signaling; GO:0044788 modulation by host of viral process; GO:0002444 myeloid leukocyte mediated immunity; GO:0050789 regulation of biological process; GO:0030030 cell projection organization; GO:0032940 secretion by cell; GO:0019054 modulation by virus of host process; GO:0044791 positive regulation by host of viral release from host cell; GO:0043299 leukocyte degranulation; GO:0048856 anatomical structure development; GO:0051851 modification by host of symbiont morphology or physiology; GO:0016043 cellular component organization; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0002252 immune effector process; GO:0048193 Golgi vesicle transport; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0023056 positive regulation of signaling; GO:0016032 viral process; GO:0010647 positive regulation of cell communication; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0045070 positive regulation of viral genome replication; GO:0046467 membrane lipid biosynthetic process; GO:0050792 regulation of viral process; GO:0016050 vesicle organization; GO:0006807 nitrogen compound metabolic process; GO:0044829 positive regulation by host of viral genome replication; GO:0051701 interaction with host; GO:0031175 neuron projection development; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0043901 negative regulation of multi-organism process; GO:0051641 cellular localization; GO:0044828 negative regulation by host of viral genome replication; GO:0002366 leukocyte activation involved in immune response; GO:0070727 cellular macromolecule localization; GO:0042119 neutrophil activation; GO:0048524 positive regulation of viral process; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling; GO:0009967 positive regulation of signal transduction; GO:0040012 regulation of locomotion; GO:1903900 regulation of viral life cycle; GO:0019048 modulation by virus of host morphology or physiology; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005911 cell-cell junction; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005765 lysosomal membrane; GO:0005856 cytoskeleton; GO:0070160 occluding junction; GO:0031965 nuclear membrane; GO:0015630 microtubule cytoskeleton; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:0044431 Golgi apparatus part; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0000323 lytic vacuole; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0005635 nuclear envelope; GO:0043232 intracellular non-membrane-bounded organelle; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0035577 azurophil granule membrane; GO:0000139 Golgi membrane; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0016021 integral component of membrane; GO:0005923 bicellular tight junction; GO:0043296 apical junction complex; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0098852 lytic vacuole membrane; GO:0042582 azurophil granule; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0030667 secretory granule membrane; GO:0005634 nucleus; GO:0044432 endoplasmic reticulum part; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0031975 envelope; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0050839 cell adhesion molecule binding; GO:0008092 cytoskeletal protein binding; GO:0046982 protein heterodimerization activity; GO:0008017 microtubule binding; GO:0005488 binding; GO:0033149 FFAT motif binding; GO:0046983 protein dimerization activity; GO:0045296 cadherin binding; GO:0015631 tubulin binding; GO:0019904 protein domain specific binding; GO:0005515 protein binding; GO:0004871 signal transducer activity; ","K06096","VAPA; vesicle-associated membrane protein-associated protein A","hsa04979 Cholesterol metabolism - Homo sapiens (human); ","IPR008962; IPR000535; ","PapD-like; Major sperm protein (MSP) domain; \r"]
["Q9P0S3","ORM1-like protein 1 OS=Homo sapiens OX=9606 GN=ORMDL1","ORMDL1",17.371,3.0477,7.2,1,1,1,0.951,0.96,0.987,1.103,0.944,1.061,1.072,0.231,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0065008 regulation of biological quality; GO:0006643 membrane lipid metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0006672 ceramide metabolic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0044087 regulation of cellular component biogenesis; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0019216 regulation of lipid metabolic process; GO:0044237 cellular metabolic process; GO:0055082 cellular chemical homeostasis; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0008152 metabolic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0006665 sphingolipid metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0090156 cellular sphingolipid homeostasis; GO:2000303 regulation of ceramide biosynthetic process; GO:0009987 cellular process; GO:0055088 lipid homeostasis; GO:0048878 chemical homeostasis; GO:0006629 lipid metabolic process; GO:0045833 negative regulation of lipid metabolic process; GO:0051055 negative regulation of lipid biosynthetic process; GO:0090153 regulation of sphingolipid biosynthetic process; GO:1905038 regulation of membrane lipid metabolic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:0019725 cellular homeostasis; GO:0034249 negative regulation of cellular amide metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0043603 cellular amide metabolic process; GO:0044238 primary metabolic process; GO:0090155 negative regulation of sphingolipid biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0009892 negative regulation of metabolic process; GO:0034248 regulation of cellular amide metabolic process; GO:0009890 negative regulation of biosynthetic process; GO:1900060 negative regulation of ceramide biosynthetic process; GO:0050789 regulation of biological process; GO:0044710 single-organism metabolic process; GO:0046890 regulation of lipid biosynthetic process; GO:0019222 regulation of metabolic process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0002178 palmitoyltransferase complex; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031224 intrinsic component of membrane; GO:0032991 macromolecular complex; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:1990234 transferase complex; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:1902494 catalytic complex; GO:0035339 SPOTS complex; GO:0031211 endoplasmic reticulum palmitoyltransferase complex; GO:0044432 endoplasmic reticulum part; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0017059 serine C-palmitoyltransferase complex; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; "]
["Q9P1F3","Costars family protein ABRACL OS=Homo sapiens OX=9606 GN=ABRACL","ABRACL",9.0564,11.965,19.8,1,2,1,1.041,1.1,1.142,0.982,0.912,0.845,0.834,0.0233,"cytoplasm\r",{"$nulls":6},"IPR027817; ","Costars domain; \r"]
["Q9P206","Uncharacterized protein KIAA1522 OS=Homo sapiens OX=9606 GN=KIAA1522","KIAA1522",107.09,1.7653,1.2,1,1,1,0.993,0.909,0.908,1.08,1.101,1.011,1.136,0.0314,"nucleus\r","GO:0032502 developmental process; GO:0030154 cell differentiation; GO:0044767 single-organism developmental process; GO:0048869 cellular developmental process; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0009987 cellular process; "]
["Q9P260","LisH domain and HEAT repeat-containing protein KIAA1468 OS=Homo sapiens OX=9606 GN=KIAA1468","KIAA1468",134.63,12.511,5,6,6,6,0.738,0.698,0.867,1.324,1.049,1.303,1.596,0.00934,"nucleus\r",null,null,"GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR011989; IPR016024; IPR006594; ","Armadillo-like helical; Armadillo-type fold; LIS1 homology motif; \r"]
["Q9P291","Armadillo repeat-containing X-linked protein 1 OS=Homo sapiens OX=9606 GN=ARMCX1","ARMCX1",49.18,3.895,2.4,1,2,1,1.174,1.263,1.064,0.918,0.8,0.82,0.725,0.00794,"endoplasmic reticulum\r",null,"GO:0031224 intrinsic component of membrane; GO:0016020 membrane; GO:0016021 integral component of membrane; GO:0044425 membrane part; ","GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR006911; IPR011989; IPR016024; ","Armadillo repeat-containing domain; Armadillo-like helical; Armadillo-type fold; \r"]
["Q9P2E3","NFX1-type zinc finger-containing protein 1 OS=Homo sapiens OX=9606 GN=ZNFX1","ZNFX1",220.22,1.8547,0.4,1,1,1,0.973,1.008,0.841,1.051,1.053,1.078,1.128,0.159,"cyto_nucl\r","GO:0050794 regulation of cellular process; GO:0010468 regulation of gene expression; GO:0006355 regulation of transcription, DNA-templated; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0051252 regulation of RNA metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0009889 regulation of biosynthetic process; GO:0019222 regulation of metabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0065007 biological regulation; GO:2000112 regulation of cellular macromolecule biosynthetic process; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0046914 transition metal ion binding; GO:0005488 binding; GO:0001071 nucleic acid binding transcription factor activity; GO:0003676 nucleic acid binding; GO:0043167 ion binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0008270 zinc ion binding; GO:0003700 transcription factor activity, sequence-specific DNA binding; ",{"$nulls":3},"IPR000967; IPR027417; IPR016024; ","\"Zinc finger, NF-X1-type; P-loop containing nucleoside triphosphate hydrolase; Armadillo-type fold; \"\r"]
["Q9P2J5","Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS","LARS",134.46,70.666,16.2,17,21,17,0.947,0.911,0.961,1.074,1.034,1.066,1.126,0.00384,"nucleus\r","GO:0065008 regulation of biological quality; GO:0006518 peptide metabolic process; GO:0010608 posttranscriptional regulation of gene expression; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0006418 tRNA aminoacylation for protein translation; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006412 translation; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0043043 peptide biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0016070 RNA metabolic process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0006438 valyl-tRNA aminoacylation; GO:0090304 nucleic acid metabolic process; GO:0006429 leucyl-tRNA aminoacylation; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006082 organic acid metabolic process; GO:0043436 oxoacid metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0044267 cellular protein metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0043039 tRNA aminoacylation; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006448 regulation of translational elongation; GO:0006450 regulation of translational fidelity; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0034248 regulation of cellular amide metabolic process; GO:0006399 tRNA metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0051246 regulation of protein metabolic process; GO:0006417 regulation of translation; GO:0019752 carboxylic acid metabolic process; GO:0043038 amino acid activation; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0034660 ncRNA metabolic process; GO:0065007 biological regulation; GO:1901564 organonitrogen compound metabolic process; ","GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds; GO:0052689 carboxylic ester hydrolase activity; GO:1901265 nucleoside phosphate binding; GO:0016875 ligase activity, forming carbon-oxygen bonds; GO:0016874 ligase activity; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0004823 leucine-tRNA ligase activity; GO:0004832 valine-tRNA ligase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0004812 aminoacyl-tRNA ligase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0002161 aminoacyl-tRNA editing activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; ","K01869","LARS; leucyl-tRNA synthetase [EC:6.1.1.4]","hsa00970 Aminoacyl-tRNA biosynthesis - Homo sapiens (human); ","IPR014729; IPR013155; IPR009008; IPR002300; IPR009080; ","\"Rossmann-like alpha/beta/alpha sandwich fold; Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding; Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain; Aminoacyl-tRNA synthetase, class Ia; Aminoacyl-tRNA synthetase, class Ia, anticodon-binding; \"\r"]
["Q9P2T1","GMP reductase 2 OS=Homo sapiens OX=9606 GN=GMPR2","GMPR2",37.874,24.915,17.8,6,6,5,1.071,1.031,0.883,1.023,0.966,1.039,1.014,0.798,"cytoplasm\r","GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009259 ribonucleotide metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:1901068 guanosine-containing compound metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0019693 ribose phosphate metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0009119 ribonucleoside metabolic process; GO:0046037 GMP metabolic process; GO:0018130 heterocycle biosynthetic process; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0006144 purine nucleobase metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0006163 purine nucleotide metabolic process; GO:0046128 purine ribonucleoside metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0043094 cellular metabolic compound salvage; GO:0072522 purine-containing compound biosynthetic process; GO:0044710 single-organism metabolic process; GO:0009112 nucleobase metabolic process; GO:0019637 organophosphate metabolic process; GO:0009126 purine nucleoside monophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0043101 purine-containing compound salvage; GO:1901362 organic cyclic compound biosynthetic process; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:1902494 catalytic complex; GO:0005622 intracellular; GO:0044464 cell part; GO:1990204 oxidoreductase complex; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:1902560 GMP reductase complex; GO:0005829 cytosol; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0003920 GMP reductase activity; GO:0016657 oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor; GO:0016491 oxidoreductase activity; ","K00364","E1.7.1.7; GMP reductase [EC:1.7.1.7]","hsa00230 Purine metabolism - Homo sapiens (human); ","IPR013785; IPR001093; ","Aldolase-type TIM barrel; IMP dehydrogenase/GMP reductase; \r"]
["Q9P2W9","Syntaxin-18 OS=Homo sapiens OX=9606 GN=STX18","STX18",38.673,7.1523,5.1,3,3,3,1.016,1.042,0.951,0.982,0.98,1.038,0.997,0.941,"peroxisome\r","GO:0060627 regulation of vesicle-mediated transport; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:1903358 regulation of Golgi organization; GO:0010256 endomembrane system organization; GO:0048193 Golgi vesicle transport; GO:0044699 single-organism process; GO:0044087 regulation of cellular component biogenesis; GO:1902115 regulation of organelle assembly; GO:0015031 protein transport; GO:0060341 regulation of cellular localization; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport; GO:0051649 establishment of localization in cell; GO:0032879 regulation of localization; GO:0060628 regulation of ER to Golgi vesicle-mediated transport; GO:0006886 intracellular protein transport; GO:0034613 cellular protein localization; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0009987 cellular process; GO:0032388 positive regulation of intracellular transport; GO:0051049 regulation of transport; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0033043 regulation of organelle organization; GO:0061025 membrane fusion; GO:0044802 single-organism membrane organization; GO:0032386 regulation of intracellular transport; GO:0071702 organic substance transport; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0051050 positive regulation of transport; GO:0006810 transport; GO:0045184 establishment of protein localization; GO:0090158 endoplasmic reticulum membrane organization; GO:0070727 cellular macromolecule localization; GO:0050789 regulation of biological process; GO:0010638 positive regulation of organelle organization; GO:0006890 retrograde vesicle-mediated transport, Golgi to ER; GO:1902117 positive regulation of organelle assembly; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0044089 positive regulation of cellular component biogenesis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:0007029 endoplasmic reticulum organization; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0098588 bounding membrane of organelle; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0000139 Golgi membrane; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044432 endoplasmic reticulum part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0044431 Golgi apparatus part; GO:0043234 protein complex; GO:0005794 Golgi apparatus; GO:0043227 membrane-bounded organelle; GO:0031201 SNARE complex; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; ","GO:0005484 SNAP receptor activity; GO:0019904 protein domain specific binding; GO:0005515 protein binding; GO:0005488 binding; ","K08492","STX18; syntaxin 18","hsa04130 SNARE interactions in vesicular transport - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); ","IPR019529; ","\"SNARE-complex protein Syntaxin-18, N-terminal; \"\r"]
["Q9UBC2","Epidermal growth factor receptor substrate 15-like 1 OS=Homo sapiens OX=9606 GN=EPS15L1","EPS15L1",94.254,34.2,9.3,7,7,7,0.924,1.103,1.044,0.929,1.07,0.992,0.974,0.722,"nucleus\r","GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0009968 negative regulation of signal transduction; GO:1901185 negative regulation of ERBB signaling pathway; GO:0016192 vesicle-mediated transport; GO:0023051 regulation of signaling; GO:0048585 negative regulation of response to stimulus; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0006897 endocytosis; GO:0051234 establishment of localization; GO:0006810 transport; GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway; GO:0023057 negative regulation of signaling; GO:0050789 regulation of biological process; GO:0010646 regulation of cell communication; GO:0010648 negative regulation of cell communication; GO:1901184 regulation of ERBB signaling pathway; GO:0061024 membrane organization; GO:0048583 regulation of response to stimulus; GO:0042058 regulation of epidermal growth factor receptor signaling pathway; GO:0051179 localization; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0098796 membrane protein complex; GO:0071944 cell periphery; GO:0048475 coated membrane; GO:0005737 cytoplasm; GO:0098797 plasma membrane protein complex; GO:0032991 macromolecular complex; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0098589 membrane region; GO:0030118 clathrin coat; GO:0030132 clathrin coat of coated pit; GO:0030117 membrane coat; GO:0043234 protein complex; GO:0005905 clathrin-coated pit; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0050839 cell adhesion molecule binding; GO:0005488 binding; GO:0043167 ion binding; GO:0045296 cadherin binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0005509 calcium ion binding; ","K12472","EPS15; epidermal growth factor receptor substrate 15","hsa04144 Endocytosis - Homo sapiens (human); ","IPR000261; IPR002048; IPR011992; ","EH domain; EF-hand domain; EF-hand domain pair; \r"]
["Q9UBE0","SUMO-activating enzyme subunit 1 OS=Homo sapiens OX=9606 GN=SAE1","SAE1",38.449,63.637,40.8,12,15,12,0.937,0.967,0.965,1.066,1.017,1.021,1.082,0.0124,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0016925 protein sumoylation; GO:1903955 positive regulation of protein targeting to mitochondrion; GO:0090316 positive regulation of intracellular protein transport; GO:1903829 positive regulation of cellular protein localization; GO:1903533 regulation of protein targeting; GO:0044267 cellular protein metabolic process; GO:0010821 regulation of mitochondrion organization; GO:0044237 cellular metabolic process; GO:0070201 regulation of establishment of protein localization; GO:1903749 positive regulation of establishment of protein localization to mitochondrion; GO:0060341 regulation of cellular localization; GO:0071704 organic substance metabolic process; GO:0051130 positive regulation of cellular component organization; GO:0018205 peptidyl-lysine modification; GO:0008152 metabolic process; GO:0032879 regulation of localization; GO:1903747 regulation of establishment of protein localization to mitochondrion; GO:0044093 positive regulation of molecular function; GO:0032880 regulation of protein localization; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0033157 regulation of intracellular protein transport; GO:0009987 cellular process; GO:0016567 protein ubiquitination; GO:0032388 positive regulation of intracellular transport; GO:0051049 regulation of transport; GO:0048522 positive regulation of cellular process; GO:0033043 regulation of organelle organization; GO:1903214 regulation of protein targeting to mitochondrion; GO:0032386 regulation of intracellular transport; GO:0070647 protein modification by small protein conjugation or removal; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0051050 positive regulation of transport; GO:0010822 positive regulation of mitochondrion organization; GO:0018193 peptidyl-amino acid modification; GO:0050789 regulation of biological process; GO:1904951 positive regulation of establishment of protein localization; GO:0032446 protein modification by small protein conjugation; GO:0010638 positive regulation of organelle organization; GO:0050790 regulation of catalytic activity; GO:0044260 cellular macromolecule metabolic process; GO:0065009 regulation of molecular function; GO:0051223 regulation of protein transport; GO:0006464 cellular protein modification process; GO:0051128 regulation of cellular component organization; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:0051222 positive regulation of protein transport; GO:1903827 regulation of cellular protein localization; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0031510 SUMO activating enzyme complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0008641 small protein activating enzyme activity; GO:0030234 enzyme regulator activity; GO:0046982 protein heterodimerization activity; GO:0043008 ATP-dependent protein binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0004839 ubiquitin activating enzyme activity; GO:0046983 protein dimerization activity; GO:0016874 ligase activity; GO:0008022 protein C-terminus binding; GO:0016877 ligase activity, forming carbon-sulfur bonds; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0008047 enzyme activator activity; ","K10684","UBLE1A; ubiquitin-like 1-activating enzyme E1 A [EC:6.2.1.45]","hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human); ","IPR000594; IPR016040; ","THIF-type NAD/FAD binding fold; NAD(P)-binding domain; \r"]
["Q9UBI1","COMM domain-containing protein 3 OS=Homo sapiens OX=9606 GN=COMMD3","COMMD3",22.151,10.312,12.3,2,3,2,0.989,1.06,1.045,1.029,0.932,0.959,0.944,0.183,"cyto_nucl\r","GO:0045321 leukocyte activation; GO:0097659 nucleic acid-templated transcription; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0043170 macromolecule metabolic process; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0010468 regulation of gene expression; GO:0002443 leukocyte mediated immunity; GO:0018130 heterocycle biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0006814 sodium ion transport; GO:0002444 myeloid leukocyte mediated immunity; GO:0016070 RNA metabolic process; GO:0006810 transport; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0032940 secretion by cell; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0043299 leukocyte degranulation; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0002283 neutrophil activation involved in immune response; GO:0006725 cellular aromatic compound metabolic process; GO:0002252 immune effector process; GO:0030001 metal ion transport; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0006812 cation transport; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0036230 granulocyte activation; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006355 regulation of transcription, DNA-templated; GO:0016192 vesicle-mediated transport; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0002376 immune system process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0043312 neutrophil degranulation; GO:0044238 primary metabolic process; GO:0002263 cell activation involved in immune response; GO:0051252 regulation of RNA metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0002366 leukocyte activation involved in immune response; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0006811 ion transport; GO:0001775 cell activation; GO:0010467 gene expression; GO:0006955 immune response; GO:0051179 localization; GO:0015672 monovalent inorganic cation transport; GO:0006887 exocytosis; GO:0065007 biological regulation; ","GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0031410 cytoplasmic vesicle; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0101002 ficolin-1-rich granule; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR017920; ","COMM domain; \r"]
["Q9UBI6","Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 OS=Homo sapiens OX=9606 GN=GNG12","GNG12",8.0061,43.641,56.9,3,7,3,1.033,1.045,1.037,0.969,0.964,0.985,0.937,0.000877,"nucleus\r","GO:0021543 pallium development; GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0044707 single-multicellular organism process; GO:0007420 brain development; GO:0071310 cellular response to organic substance; GO:1901700 response to oxygen-containing compound; GO:0044699 single-organism process; GO:0021987 cerebral cortex development; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0009607 response to biotic stimulus; GO:0021537 telencephalon development; GO:0009605 response to external stimulus; GO:0033993 response to lipid; GO:0071377 cellular response to glucagon stimulus; GO:0007165 signal transduction; GO:1901653 cellular response to peptide; GO:0007154 cell communication; GO:0071375 cellular response to peptide hormone stimulus; GO:0009719 response to endogenous stimulus; GO:0030900 forebrain development; GO:0060322 head development; GO:0007275 multicellular organism development; GO:1901652 response to peptide; GO:0009987 cellular process; GO:0009617 response to bacterium; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0032496 response to lipopolysaccharide; GO:0048731 system development; GO:0002237 response to molecule of bacterial origin; GO:0010033 response to organic substance; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0071417 cellular response to organonitrogen compound; GO:0007186 G-protein coupled receptor signaling pathway; GO:0048513 animal organ development; GO:0010243 response to organonitrogen compound; GO:0050789 regulation of biological process; GO:1901701 cellular response to oxygen-containing compound; GO:0042221 response to chemical; GO:0043434 response to peptide hormone; GO:1901699 cellular response to nitrogen compound; GO:0007417 central nervous system development; GO:0044767 single-organism developmental process; GO:0071495 cellular response to endogenous stimulus; GO:0032870 cellular response to hormone stimulus; GO:1901698 response to nitrogen compound; GO:0033762 response to glucagon; GO:0009725 response to hormone; GO:0048856 anatomical structure development; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0019898 extrinsic component of membrane; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0031234 extrinsic component of cytoplasmic side of plasma membrane; GO:0009898 cytoplasmic side of plasma membrane; GO:0098562 cytoplasmic side of membrane; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:1902494 catalytic complex; GO:0005834 heterotrimeric G-protein complex; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0005884 actin filament; GO:0043227 membrane-bounded organelle; GO:0098552 side of membrane; GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:1905360 GTPase complex; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0098797 plasma membrane protein complex; GO:0019897 extrinsic component of plasma membrane; GO:0015629 actin cytoskeleton; GO:0005576 extracellular region; GO:0099081 supramolecular polymer; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0043234 protein complex; GO:0043230 extracellular organelle; ","GO:0005488 binding; GO:0043167 ion binding; GO:0042301 phosphate ion binding; GO:0043168 anion binding; GO:0005515 protein binding; GO:0019904 protein domain specific binding; GO:0030165 PDZ domain binding; GO:0004871 signal transducer activity; ","K04347","GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12","hsa04728 Dopaminergic synapse - Homo sapiens (human); hsa04371 Apelin signaling pathway - Homo sapiens (human); hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human); hsa04014 Ras signaling pathway - Homo sapiens (human); hsa05167 Kaposi's sarcoma-associated herpesvirus infection - Homo sapiens (human); hsa04010 MAPK signaling pathway - Homo sapiens (human); hsa04726 Serotonergic synapse - Homo sapiens (human); hsa04724 Glutamatergic synapse - Homo sapiens (human); hsa04062 Chemokine signaling pathway - Homo sapiens (human); hsa05200 Pathways in cancer - Homo sapiens (human); hsa04727 GABAergic synapse - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human); hsa05034 Alcoholism - Homo sapiens (human); hsa04926 Relaxin signaling pathway - Homo sapiens (human); hsa04713 Circadian entrainment - Homo sapiens (human); hsa05032 Morphine addiction - Homo sapiens (human); hsa04725 Cholinergic synapse - Homo sapiens (human); ","IPR015898; ","G-protein gamma-like domain; \r"]
["Q9UBQ0","Vacuolar protein sorting-associated protein 29 OS=Homo sapiens OX=9606 GN=VPS29","VPS29",20.505,32.027,40.1,7,12,7,1.042,0.94,0.9,0.997,1.001,1.047,1.057,0.287,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0046907 intracellular transport; GO:0007166 cell surface receptor signaling pathway; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:1990126 retrograde transport, endosome to plasma membrane; GO:0016055 Wnt signaling pathway; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0016482 cytosolic transport; GO:0009987 cellular process; GO:0051716 cellular response to stimulus; GO:0098876 vesicle-mediated transport to the plasma membrane; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0071702 organic substance transport; GO:0023052 signaling; GO:0051641 cellular localization; GO:0198738 cell-cell signaling by wnt; GO:0016197 endosomal transport; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0042147 retrograde transport, endosome to Golgi; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0007267 cell-cell signaling; GO:0051179 localization; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0030904 retromer complex; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0030906 retromer, cargo-selective complex; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0010008 endosome membrane; GO:0098588 bounding membrane of organelle; GO:0005770 late endosome; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0005488 binding; GO:0043167 ion binding; ","K18467","VPS29; vacuolar protein sorting-associated protein 29","hsa04144 Endocytosis - Homo sapiens (human); ","IPR029052; IPR024654; ","\"Metallo-dependent phosphatase-like; Calcineurin-like phosphoesterase domain, lpxH type; \"\r"]
["Q9UBQ7","Glyoxylate reductase/hydroxypyruvate reductase OS=Homo sapiens OX=9606 GN=GRHPR","GRHPR",35.668,69.316,25,7,11,7,1.007,0.989,1.017,1.001,0.945,0.988,0.974,0.236,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:0016043 cellular component organization; GO:0043648 dicarboxylic acid metabolic process; GO:0003008 system process; GO:0071822 protein complex subunit organization; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006081 cellular aldehyde metabolic process; GO:0044699 single-organism process; GO:0032501 multicellular organismal process; GO:0044237 cellular metabolic process; GO:0051259 protein oligomerization; GO:0043933 macromolecular complex subunit organization; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0007588 excretion; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0044710 single-organism metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0070271 protein complex biogenesis; GO:0006082 organic acid metabolic process; GO:0046487 glyoxylate metabolic process; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0043436 oxoacid metabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0044439 peroxisomal part; GO:0005777 peroxisome; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044438 microbody part; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0031907 microbody lumen; GO:0070013 intracellular organelle lumen; GO:0005782 peroxisomal matrix; GO:0005622 intracellular; GO:0044464 cell part; GO:0042579 microbody; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0046983 protein dimerization activity; GO:0070402 NADPH binding; GO:0043167 ion binding; GO:0043177 organic acid binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0048037 cofactor binding; GO:0016618 hydroxypyruvate reductase activity; GO:0030267 glyoxylate reductase (NADP) activity; GO:0016491 oxidoreductase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016614 oxidoreductase activity, acting on CH-OH group of donors; GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; GO:0042802 identical protein binding; GO:0031406 carboxylic acid binding; GO:0008465 glycerate dehydrogenase activity; GO:0051287 NAD binding; GO:0003824 catalytic activity; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0050661 NADP binding; GO:0043168 anion binding; GO:0050662 coenzyme binding; GO:0036094 small molecule binding; ","K00049","GRHPR; glyoxylate/hydroxypyruvate reductase [EC:1.1.1.79 1.1.1.81]","hsa00620 Pyruvate metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00260 Glycine, serine and threonine metabolism - Homo sapiens (human); hsa00630 Glyoxylate and dicarboxylate metabolism - Homo sapiens (human); ","IPR006139; IPR006140; IPR016040; ","\"D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain; NAD(P)-binding domain; \"\r"]
["Q9UBT2","SUMO-activating enzyme subunit 2 OS=Homo sapiens OX=9606 GN=UBA2","UBA2",71.223,90.63,18.4,11,15,11,0.971,1.005,0.932,0.968,0.999,1.078,1.047,0.305,"plasma membrane\r","GO:0016925 protein sumoylation; GO:0044267 cellular protein metabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0043085 positive regulation of catalytic activity; GO:0071704 organic substance metabolic process; GO:0018193 peptidyl-amino acid modification; GO:0018205 peptidyl-lysine modification; GO:0008152 metabolic process; GO:0032446 protein modification by small protein conjugation; GO:0050790 regulation of catalytic activity; GO:0044093 positive regulation of molecular function; GO:0044260 cellular macromolecule metabolic process; GO:0065009 regulation of molecular function; GO:0006464 cellular protein modification process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:0009987 cellular process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0031510 SUMO activating enzyme complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0046983 protein dimerization activity; GO:0016874 ligase activity; GO:0005515 protein binding; GO:0016877 ligase activity, forming carbon-sulfur bonds; GO:0098772 molecular function regulator; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0008047 enzyme activator activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0008641 small protein activating enzyme activity; GO:0005524 ATP binding; GO:0046982 protein heterodimerization activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0019948 SUMO activating enzyme activity; GO:0030234 enzyme regulator activity; GO:0046872 metal ion binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0008134 transcription factor binding; GO:0036094 small molecule binding; ","K10685","UBLE1B; ubiquitin-like 1-activating enzyme E1 B [EC:6.2.1.45]","hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human); ","IPR032426; IPR019572; IPR000594; IPR028077; IPR016040; ","\"SUMO-activating enzyme subunit 2, C-terminal domain; Ubiquitin-activating enzyme, catalytic cysteine domain; THIF-type NAD/FAD binding fold; Ubiquitin/SUMO-activating enzyme ubiquitin-like domain; NAD(P)-binding domain; \"\r"]
["Q9UBU9","Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1","NXF1",70.182,9.2359,4.8,2,2,2,0.895,0.897,0.903,1.008,1.162,1.126,1.223,0.0438,"nucleus\r","GO:0050658 RNA transport; GO:0046907 intracellular transport; GO:0051028 mRNA transport; GO:0016973 poly(A)+ mRNA export from nucleus; GO:0051168 nuclear export; GO:0051169 nuclear transport; GO:0044764 multi-organism cellular process; GO:0015031 protein transport; GO:0051236 establishment of RNA localization; GO:0051234 establishment of localization; GO:0071704 organic substance metabolic process; GO:0071427 mRNA-containing ribonucleoprotein complex export from nucleus; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0050657 nucleic acid transport; GO:0016032 viral process; GO:0015931 nucleobase-containing compound transport; GO:0006886 intracellular protein transport; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0033036 macromolecule localization; GO:0034613 cellular protein localization; GO:0008104 protein localization; GO:0009987 cellular process; GO:0006406 mRNA export from nucleus; GO:0006403 RNA localization; GO:0006405 RNA export from nucleus; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0071702 organic substance transport; GO:0006611 protein export from nucleus; GO:0051704 multi-organism process; GO:0071166 ribonucleoprotein complex localization; GO:0051641 cellular localization; GO:0006810 transport; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0071426 ribonucleoprotein complex export from nucleus; GO:0006913 nucleocytoplasmic transport; GO:0010467 gene expression; GO:0051179 localization; GO:0071705 nitrogen compound transport; ","GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005643 nuclear pore; GO:0005635 nuclear envelope; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0016234 inclusion body; GO:0042405 nuclear inclusion body; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0031975 envelope; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003729 mRNA binding; GO:0003723 RNA binding; GO:1901265 nucleoside phosphate binding; GO:0005487 nucleocytoplasmic transporter activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0003727 single-stranded RNA binding; GO:0036094 small molecule binding; GO:0005215 transporter activity; ","K14284","NXF; nuclear RNA export factor","hsa03015 mRNA surveillance pathway - Homo sapiens (human); hsa03008 Ribosome biogenesis in eukaryotes - Homo sapiens (human); hsa05168 Herpes simplex infection - Homo sapiens (human); hsa03013 RNA transport - Homo sapiens (human); hsa05164 Influenza A - Homo sapiens (human); ","IPR002075; IPR015245; IPR000504; IPR018222; IPR005637; IPR012677; IPR032675; IPR009060; IPR032710; ","\"Nuclear transport factor 2; Nuclear RNA export factor Tap, RNA-binding domain; RNA recognition motif domain; Nuclear transport factor 2, eukaryote; TAP C-terminal (TAP-C) domain; Nucleotide-binding alpha-beta plait domain; Leucine-rich repeat domain, L domain-like; UBA-like; NTF2-like domain; \"\r"]
["Q9UBX3","Mitochondrial dicarboxylate carrier OS=Homo sapiens OX=9606 GN=SLC25A10","SLC25A10",31.282,5.3866,3.5,1,1,1,0.953,1.079,1.061,0.877,1.091,0.946,0.942,0.453,"mitochondria\r","GO:0098661 inorganic anion transmembrane transport; GO:0016051 carbohydrate biosynthetic process; GO:0015709 thiosulfate transport; GO:0034220 ion transmembrane transport; GO:0019319 hexose biosynthetic process; GO:0071422 succinate transmembrane transport; GO:0006839 mitochondrial transport; GO:0044699 single-organism process; GO:0046364 monosaccharide biosynthetic process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0098656 anion transmembrane transport; GO:0071704 organic substance metabolic process; GO:0051234 establishment of localization; GO:0006006 glucose metabolic process; GO:0008152 metabolic process; GO:0006094 gluconeogenesis; GO:0008272 sulfate transport; GO:0019418 sulfide oxidation; GO:1902578 single-organism localization; GO:1903825 organic acid transmembrane transport; GO:1902356 oxaloacetate(2-) transmembrane transport; GO:0005996 monosaccharide metabolic process; GO:0006817 phosphate ion transport; GO:0009987 cellular process; GO:1905039 carboxylic acid transmembrane transport; GO:0044765 single-organism transport; GO:0015729 oxaloacetate transport; GO:0072348 sulfur compound transport; GO:0006790 sulfur compound metabolic process; GO:0044711 single-organism biosynthetic process; GO:0070221 sulfide oxidation, using sulfide:quinone oxidoreductase; GO:0098660 inorganic ion transmembrane transport; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0071423 malate transmembrane transport; GO:0044763 single-organism cellular process; GO:0071702 organic substance transport; GO:1902358 sulfate transmembrane transport; GO:0044238 primary metabolic process; GO:0005975 carbohydrate metabolic process; GO:0046942 carboxylic acid transport; GO:1901576 organic substance biosynthetic process; GO:0035435 phosphate ion transmembrane transport; GO:0015849 organic acid transport; GO:0006820 anion transport; GO:0006810 transport; GO:0044723 single-organism carbohydrate metabolic process; GO:0055085 transmembrane transport; GO:0015711 organic anion transport; GO:0015740 C4-dicarboxylate transport; GO:0015743 malate transport; GO:0006811 ion transport; GO:0044710 single-organism metabolic process; GO:0044283 small molecule biosynthetic process; GO:0006835 dicarboxylic acid transport; GO:0051179 localization; GO:0015698 inorganic anion transport; GO:0019318 hexose metabolic process; GO:0015744 succinate transport; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044429 mitochondrial part; GO:0031090 organelle membrane; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0031975 envelope; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0031966 mitochondrial membrane; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0022804 active transmembrane transporter activity; GO:0015291 secondary active transmembrane transporter activity; GO:0005310 dicarboxylic acid transmembrane transporter activity; GO:0005342 organic acid transmembrane transporter activity; GO:0015141 succinate transmembrane transporter activity; GO:0015075 ion transmembrane transporter activity; GO:0015556 C4-dicarboxylate transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0015116 sulfate transmembrane transporter activity; GO:0015297 antiporter activity; GO:0015103 inorganic anion transmembrane transporter activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:1901682 sulfur compound transmembrane transporter activity; GO:0015131 oxaloacetate transmembrane transporter activity; GO:0005488 binding; GO:1901677 phosphate transmembrane transporter activity; GO:0015140 malate transmembrane transporter activity; GO:0008514 organic anion transmembrane transporter activity; GO:0015117 thiosulfate transmembrane transporter activity; GO:0022857 transmembrane transporter activity; GO:0005215 transporter activity; GO:0046943 carboxylic acid transmembrane transporter activity; GO:0008509 anion transmembrane transporter activity; ","K13577","SLC25A10; solute carrier family 25 (mitochondrial dicarboxylate transporter), member 10","hsa04964 Proximal tubule bicarbonate reclamation - Homo sapiens (human); ","IPR023395; ","Mitochondrial carrier domain; \r"]
["Q9UBX5","Fibulin-5 OS=Homo sapiens OX=9606 GN=FBLN5","FBLN5",50.18,40.758,18.3,7,12,7,1.115,1.176,1.102,0.926,0.842,0.928,0.795,0.00366,"extracellular\r","GO:0050794 regulation of cellular process; GO:0044085 cellular component biogenesis; GO:0016043 cellular component organization; GO:0040008 regulation of growth; GO:0048251 elastic fiber assembly; GO:0044699 single-organism process; GO:0080134 regulation of response to stress; GO:0051234 establishment of localization; GO:0001558 regulation of cell growth; GO:0022610 biological adhesion; GO:1902578 single-organism localization; GO:0022607 cellular component assembly; GO:0043062 extracellular structure organization; GO:0007160 cell-matrix adhesion; GO:0007155 cell adhesion; GO:0090322 regulation of superoxide metabolic process; GO:2000121 regulation of removal of superoxide radicals; GO:0030198 extracellular matrix organization; GO:0034613 cellular protein localization; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0009987 cellular process; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0034394 protein localization to cell surface; GO:0044763 single-organism cellular process; GO:0085029 extracellular matrix assembly; GO:0031323 regulation of cellular metabolic process; GO:0051641 cellular localization; GO:0006810 transport; GO:0070727 cellular macromolecule localization; GO:0050789 regulation of biological process; GO:1900407 regulation of cellular response to oxidative stress; GO:0080135 regulation of cellular response to stress; GO:0031589 cell-substrate adhesion; GO:0048583 regulation of response to stimulus; GO:0019222 regulation of metabolic process; GO:0051128 regulation of cellular component organization; GO:1902882 regulation of response to oxidative stress; GO:0051179 localization; GO:2000377 regulation of reactive oxygen species metabolic process; GO:1901031 regulation of response to reactive oxygen species; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0031012 extracellular matrix; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0005578 proteinaceous extracellular matrix; GO:0071953 elastic fiber; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0044420 extracellular matrix component; GO:0043230 extracellular organelle; ","GO:0005102 receptor binding; GO:0043167 ion binding; GO:0046983 protein dimerization activity; GO:0044877 macromolecular complex binding; GO:0005515 protein binding; GO:0005178 integrin binding; GO:0050839 cell adhesion molecule binding; GO:0042802 identical protein binding; GO:0005488 binding; GO:0042803 protein homodimerization activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0008022 protein C-terminus binding; GO:0005509 calcium ion binding; GO:0032403 protein complex binding; ","K17340",null,null,"IPR026823; IPR001881; IPR000742; IPR009030; ","Complement Clr-like EGF domain; EGF-like calcium-binding domain; EGF-like domain; Growth factor receptor cysteine-rich domain; \r"]
["Q9UDW1","Cytochrome b-c1 complex subunit 9 OS=Homo sapiens OX=9606 GN=UQCR10","UQCR10",7.3084,12.121,39.7,2,2,2,1.044,1,1.05,0.935,1.029,0.952,0.942,0.145,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0034551 mitochondrial respiratory chain complex III assembly; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0022607 cellular component assembly; GO:0006753 nucleoside phosphate metabolic process; GO:0065003 macromolecular complex assembly; GO:0007005 mitochondrion organization; GO:0019693 ribose phosphate metabolic process; GO:0044765 single-organism transport; GO:0071822 protein complex subunit organization; GO:0098655 cation transmembrane transport; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0006119 oxidative phosphorylation; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0006810 transport; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0022900 electron transport chain; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0070271 protein complex biogenesis; GO:0033108 mitochondrial respiratory chain complex assembly; GO:0098662 inorganic cation transmembrane transport; GO:0016043 cellular component organization; GO:0016310 phosphorylation; GO:0034220 ion transmembrane transport; GO:0017004 cytochrome complex assembly; GO:0006725 cellular aromatic compound metabolic process; GO:0042773 ATP synthesis coupled electron transport; GO:0009259 ribonucleotide metabolic process; GO:0022904 respiratory electron transport chain; GO:0071704 organic substance metabolic process; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0006812 cation transport; GO:0006139 nucleobase-containing compound metabolic process; GO:1902600 hydrogen ion transmembrane transport; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009119 ribonucleoside metabolic process; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0043623 cellular protein complex assembly; GO:0046034 ATP metabolic process; GO:0017062 respiratory chain complex III assembly; GO:0034622 cellular macromolecular complex assembly; GO:0098660 inorganic ion transmembrane transport; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0045333 cellular respiration; GO:0006163 purine nucleotide metabolic process; GO:0015992 proton transport; GO:0006818 hydrogen transport; GO:0043933 macromolecular complex subunit organization; GO:0046128 purine ribonucleoside metabolic process; GO:0055085 transmembrane transport; GO:0006793 phosphorus metabolic process; GO:0006811 ion transport; GO:0009060 aerobic respiration; GO:0006996 organelle organization; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0051179 localization; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:0015672 monovalent inorganic cation transport; GO:0097033 mitochondrial respiratory chain complex III biogenesis; GO:1901564 organonitrogen compound metabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0098798 mitochondrial protein complex; GO:0005623 cell; GO:0044455 mitochondrial membrane part; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0070062 extracellular exosome; GO:1902494 catalytic complex; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005750 mitochondrial respiratory chain complex III; GO:0019866 organelle inner membrane; GO:1903561 extracellular vesicle; GO:1990351 transporter complex; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0098803 respiratory chain complex; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0070069 cytochrome complex; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:1902495 transmembrane transporter complex; GO:0016021 integral component of membrane; GO:0045275 respiratory chain complex III; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005746 mitochondrial respiratory chain; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:1990204 oxidoreductase complex; GO:0031975 envelope; GO:0043234 protein complex; GO:0070469 respiratory chain; GO:0031966 mitochondrial membrane; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0008121 ubiquinol-cytochrome-c reductase activity; GO:0015075 ion transmembrane transporter activity; GO:0016679 oxidoreductase activity, acting on diphenols and related substances as donors; GO:0003824 catalytic activity; GO:0022892 substrate-specific transporter activity; GO:0015077 monovalent inorganic cation transmembrane transporter activity; GO:0022890 inorganic cation transmembrane transporter activity; GO:0015078 hydrogen ion transmembrane transporter activity; GO:0008324 cation transmembrane transporter activity; GO:0016681 oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor; GO:0022891 substrate-specific transmembrane transporter activity; GO:0022857 transmembrane transporter activity; GO:0005215 transporter activity; GO:0016491 oxidoreductase activity; ","K00419","QCR9; ubiquinol-cytochrome c reductase subunit 9","hsa04260 Cardiac muscle contraction - Homo sapiens (human); hsa05010 Alzheimer's disease - Homo sapiens (human); hsa04932 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa04714 Thermogenesis - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); "]
["Q9UEW8","STE20/SPS1-related proline-alanine-rich protein kinase OS=Homo sapiens OX=9606 GN=STK39","STK39",59.473,31.126,15,6,7,4,0.976,1.108,1.22,0.891,0.886,0.934,0.821,0.0439,"cytoplasm\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:2000681 negative regulation of rubidium ion transport; GO:1901017 negative regulation of potassium ion transmembrane transporter activity; GO:0010766 negative regulation of sodium ion transport; GO:0031347 regulation of defense response; GO:1902306 negative regulation of sodium ion transmembrane transport; GO:0006971 hypotonic response; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0044057 regulation of system process; GO:0032414 positive regulation of ion transmembrane transporter activity; GO:0018105 peptidyl-serine phosphorylation; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0032891 negative regulation of organic acid transport; GO:0023016 signal transduction by trans-phosphorylation; GO:0051953 negative regulation of amine transport; GO:0051051 negative regulation of transport; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0071214 cellular response to abiotic stimulus; GO:0080090 regulation of primary metabolic process; GO:0051956 negative regulation of amino acid transport; GO:0044763 single-organism cellular process; GO:0043269 regulation of ion transport; GO:2000649 regulation of sodium ion transmembrane transporter activity; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:1903959 regulation of anion transmembrane transport; GO:0034762 regulation of transmembrane transport; GO:0044710 single-organism metabolic process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0071470 cellular response to osmotic stress; GO:0006464 cellular protein modification process; GO:0090188 negative regulation of pancreatic juice secretion; GO:0032412 regulation of ion transmembrane transporter activity; GO:0003013 circulatory system process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0044707 single-multicellular organism process; GO:0016310 phosphorylation; GO:0043267 negative regulation of potassium ion transport; GO:2000680 regulation of rubidium ion transport; GO:0002028 regulation of sodium ion transport; GO:0034764 positive regulation of transmembrane transport; GO:1901380 negative regulation of potassium ion transmembrane transport; GO:0009628 response to abiotic stimulus; GO:0018210 peptidyl-threonine modification; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:2000686 regulation of rubidium ion transmembrane transporter activity; GO:0080134 regulation of response to stress; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0032844 regulation of homeostatic process; GO:2000650 negative regulation of sodium ion transmembrane transporter activity; GO:0051239 regulation of multicellular organismal process; GO:0060249 anatomical structure homeostasis; GO:0018107 peptidyl-threonine phosphorylation; GO:0010959 regulation of metal ion transport; GO:0001933 negative regulation of protein phosphorylation; GO:1903789 regulation of amino acid transmembrane transport; GO:1904062 regulation of cation transmembrane transport; GO:0032409 regulation of transporter activity; GO:0023014 signal transduction by protein phosphorylation; GO:0034763 negative regulation of transmembrane transport; GO:0006950 response to stress; GO:1905407 regulation of creatine transmembrane transporter activity; GO:1901379 regulation of potassium ion transmembrane transport; GO:0032101 regulation of response to external stimulus; GO:0071476 cellular hypotonic response; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0034766 negative regulation of ion transmembrane transport; GO:0043270 positive regulation of ion transport; GO:0051955 regulation of amino acid transport; GO:0006793 phosphorus metabolic process; GO:1902305 regulation of sodium ion transmembrane transport; GO:0043412 macromolecule modification; GO:0045936 negative regulation of phosphate metabolic process; GO:0032890 regulation of organic acid transport; GO:0018209 peptidyl-serine modification; GO:0044070 regulation of anion transport; GO:0051046 regulation of secretion; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0036438 maintenance of lens transparency; GO:0006796 phosphate-containing compound metabolic process; GO:0048871 multicellular organismal homeostasis; GO:0031400 negative regulation of protein modification process; GO:0007165 signal transduction; GO:0043266 regulation of potassium ion transport; GO:0007154 cell communication; GO:0046777 protein autophosphorylation; GO:0043268 positive regulation of potassium ion transport; GO:0032413 negative regulation of ion transmembrane transporter activity; GO:0006970 response to osmotic stress; GO:0022898 regulation of transmembrane transporter activity; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051050 positive regulation of transport; GO:0051048 negative regulation of secretion; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0034767 positive regulation of ion transmembrane transport; GO:0090186 regulation of pancreatic juice secretion; GO:0001894 tissue homeostasis; GO:0065009 regulation of molecular function; GO:1901016 regulation of potassium ion transmembrane transporter activity; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0036211 protein modification process; GO:0008217 regulation of blood pressure; GO:2000021 regulation of ion homeostasis; GO:0032411 positive regulation of transporter activity; GO:0060255 regulation of macromolecule metabolic process; GO:1905408 negative regulation of creatine transmembrane transporter activity; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0044058 regulation of digestive system process; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0060457 negative regulation of digestive system process; GO:0051952 regulation of amine transport; GO:0006468 protein phosphorylation; GO:0042326 negative regulation of phosphorylation; GO:0032410 negative regulation of transporter activity; GO:0008015 blood circulation; GO:0009987 cellular process; GO:1903792 negative regulation of anion transport; GO:0050878 regulation of body fluid levels; GO:0003008 system process; GO:0043271 negative regulation of ion transport; GO:0035556 intracellular signal transduction; GO:0051049 regulation of transport; GO:0001932 regulation of protein phosphorylation; GO:0048518 positive regulation of biological process; GO:0018193 peptidyl-amino acid modification; GO:1904063 negative regulation of cation transmembrane transport; GO:2000687 negative regulation of rubidium ion transmembrane transporter activity; GO:0034765 regulation of ion transmembrane transport; GO:0051246 regulation of protein metabolic process; GO:1903960 negative regulation of anion transmembrane transport; GO:0010563 negative regulation of phosphorus metabolic process; GO:0050727 regulation of inflammatory response; GO:0051248 negative regulation of protein metabolic process; GO:0065007 biological regulation; ","GO:0016323 basolateral plasma membrane; GO:0016020 membrane; GO:0016324 apical plasma membrane; GO:0019898 extrinsic component of membrane; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0098590 plasma membrane region; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0045177 apical part of cell; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0019901 protein kinase binding; GO:0005515 protein binding; GO:0004672 protein kinase activity; GO:0004702 signal transducer, downstream of receptor, with serine/threonine kinase activity; GO:0004871 signal transducer activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016301 kinase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0019900 kinase binding; GO:0032549 ribonucleoside binding; GO:0005057 signal transducer activity, downstream of receptor; GO:0097367 carbohydrate derivative binding; GO:0004674 protein serine/threonine kinase activity; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019899 enzyme binding; GO:0036094 small molecule binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K08835",null,null,"IPR000719; IPR011009; IPR024678; ","\"Protein kinase domain; Protein kinase-like domain; Serine/threonine-protein kinase OSR1/WNK, CCT domain; \"\r"]
["Q9UFG5","UPF0449 protein C19orf25 OS=Homo sapiens OX=9606 GN=C19orf25","C19orf25",12.878,12.472,25.4,2,2,2,0.923,1.022,0.94,1.067,1.006,1.047,1.081,0.0923,"mitochondria\r",null,null,"GO:0005515 protein binding; GO:0005488 binding; "]
["Q9UFN0","Protein NipSnap homolog 3A OS=Homo sapiens OX=9606 GN=NIPSNAP3A","NIPSNAP3A",28.466,21.06,28.7,6,11,6,1.094,1.106,1.023,0.889,0.934,0.926,0.853,0.00526,"mitochondria\r",null,"GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR012577; IPR011008; ","NIPSNAP; Dimeric alpha-beta barrel; \r"]
["Q9UGI8","Testin OS=Homo sapiens OX=9606 GN=TES","TES",47.996,55.882,30.2,11,14,11,0.979,0.991,0.969,1.028,1.044,0.988,1.041,0.0855,"nucleus\r","GO:0050794 regulation of cellular process; GO:0050789 regulation of biological process; GO:0042127 regulation of cell proliferation; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0065007 biological regulation; GO:0008285 negative regulation of cell proliferation; ","GO:0016020 membrane; GO:0043229 intracellular organelle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0070161 anchoring junction; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:0030055 cell-substrate junction; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0005924 cell-substrate adherens junction; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0050839 cell adhesion molecule binding; GO:0003723 RNA binding; GO:0046914 transition metal ion binding; GO:0005488 binding; GO:0043167 ion binding; GO:0045296 cadherin binding; GO:0003676 nucleic acid binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0008270 zinc ion binding; ",{"$nulls":3},"IPR001781; IPR033724; IPR010442; ","\"Zinc finger, LIM-type; PET testin; PET domain; \"\r"]
["Q9UGK3","Signal-transducing adaptor protein 2 OS=Homo sapiens OX=9606 GN=STAP2","STAP2",44.893,5.1062,5,2,2,2,0.864,0.886,0.817,1.012,1.178,1.228,1.332,0.0111,"mitochondria\r","GO:0050794 regulation of cellular process; GO:0046425 regulation of JAK-STAT cascade; GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation; GO:0032270 positive regulation of cellular protein metabolic process; GO:0050730 regulation of peptidyl-tyrosine phosphorylation; GO:0042509 regulation of tyrosine phosphorylation of STAT protein; GO:0060255 regulation of macromolecule metabolic process; GO:0023051 regulation of signaling; GO:0031399 regulation of protein modification process; GO:1902533 positive regulation of intracellular signal transduction; GO:1904894 positive regulation of STAT cascade; GO:0010646 regulation of cell communication; GO:0009893 positive regulation of metabolic process; GO:0042516 regulation of tyrosine phosphorylation of Stat3 protein; GO:0023056 positive regulation of signaling; GO:0010562 positive regulation of phosphorus metabolic process; GO:0042327 positive regulation of phosphorylation; GO:0010647 positive regulation of cell communication; GO:0009966 regulation of signal transduction; GO:1904892 regulation of STAT cascade; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0045937 positive regulation of phosphate metabolic process; GO:1902531 regulation of intracellular signal transduction; GO:0080090 regulation of primary metabolic process; GO:0001932 regulation of protein phosphorylation; GO:0046427 positive regulation of JAK-STAT cascade; GO:0031401 positive regulation of protein modification process; GO:0048522 positive regulation of cellular process; GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein; GO:0001934 positive regulation of protein phosphorylation; GO:0031323 regulation of cellular metabolic process; GO:0048518 positive regulation of biological process; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0051247 positive regulation of protein metabolic process; GO:0051246 regulation of protein metabolic process; GO:0048583 regulation of response to stimulus; GO:0031325 positive regulation of cellular metabolic process; GO:0019222 regulation of metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0009967 positive regulation of signal transduction; GO:0019220 regulation of phosphate metabolic process; GO:0042517 positive regulation of tyrosine phosphorylation of Stat3 protein; GO:0048584 positive regulation of response to stimulus; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0071944 cell periphery; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005886 plasma membrane; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR000980; IPR011993; ","SH2 domain; PH domain-like; \r"]
["Q9UGL1","Lysine-specific demethylase 5B OS=Homo sapiens OX=9606 GN=KDM5B","KDM5B",175.66,2.2303,1.1,2,2,2,1.033,0.891,0.919,1.023,1.041,1.093,1.11,0.0965,"nucleus\r","GO:0048732 gland development; GO:0022414 reproductive process; GO:0097659 nucleic acid-templated transcription; GO:0016577 histone demethylation; GO:0044237 cellular metabolic process; GO:0002088 lens development in camera-type eye; GO:0048754 branching morphogenesis of an epithelial tube; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0050678 regulation of epithelial cell proliferation; GO:0044702 single organism reproductive process; GO:0009719 response to endogenous stimulus; GO:0033601 positive regulation of mammary gland epithelial cell proliferation; GO:0070848 response to growth factor; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0060763 mammary duct terminal end bud growth; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0003006 developmental process involved in reproduction; GO:0080090 regulation of primary metabolic process; GO:0001763 morphogenesis of a branching structure; GO:0035239 tube morphogenesis; GO:0019953 sexual reproduction; GO:0044763 single-organism cellular process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0044710 single-organism metabolic process; GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0009887 animal organ morphogenesis; GO:0006464 cellular protein modification process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0060603 mammary gland duct morphogenesis; GO:0051094 positive regulation of developmental process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0030855 epithelial cell differentiation; GO:0050794 regulation of cellular process; GO:0000003 reproduction; GO:0002009 morphogenesis of an epithelium; GO:0044707 single-multicellular organism process; GO:0042127 regulation of cell proliferation; GO:0016570 histone modification; GO:0044267 cellular protein metabolic process; GO:0009791 post-embryonic development; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0051239 regulation of multicellular organismal process; GO:0030879 mammary gland development; GO:0045892 negative regulation of transcription, DNA-templated; GO:0009653 anatomical structure morphogenesis; GO:0001654 eye development; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0071774 response to fibroblast growth factor; GO:0051171 regulation of nitrogen compound metabolic process; GO:0060443 mammary gland morphogenesis; GO:0007275 multicellular organism development; GO:0016569 covalent chromatin modification; GO:0061458 reproductive system development; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0060562 epithelial tube morphogenesis; GO:0033599 regulation of mammary gland epithelial cell proliferation; GO:0048731 system development; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0060560 developmental growth involved in morphogenesis; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0060992 response to fungicide; GO:0009890 negative regulation of biosynthetic process; GO:0061138 morphogenesis of a branching epithelium; GO:0051276 chromosome organization; GO:0006996 organelle organization; GO:0048589 developmental growth; GO:0043412 macromolecule modification; GO:0007423 sensory organ development; GO:0040007 growth; GO:0050793 regulation of developmental process; GO:0008284 positive regulation of cell proliferation; GO:0060065 uterus development; GO:0034720 histone H3-K4 demethylation; GO:0048869 cellular developmental process; GO:0070306 lens fiber cell differentiation; GO:0051046 regulation of secretion; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0071363 cellular response to growth factor stimulus; GO:0051253 negative regulation of RNA metabolic process; GO:0008214 protein dealkylation; GO:0061180 mammary gland epithelium development; GO:2001141 regulation of RNA biosynthetic process; GO:0048729 tissue morphogenesis; GO:0009893 positive regulation of metabolic process; GO:0006482 protein demethylation; GO:0070887 cellular response to chemical stimulus; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0032502 developmental process; GO:0035295 tube development; GO:0060429 epithelium development; GO:0010468 regulation of gene expression; GO:0009888 tissue development; GO:0031326 regulation of cellular biosynthetic process; GO:0055114 oxidation-reduction process; GO:0009636 response to toxic substance; GO:0048608 reproductive structure development; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0016070 RNA metabolic process; GO:0009566 fertilization; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:2000864 regulation of estradiol secretion; GO:0006351 transcription, DNA-templated; GO:1902679 negative regulation of RNA biosynthetic process; GO:0019222 regulation of metabolic process; GO:0006325 chromatin organization; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0016043 cellular component organization; GO:0043010 camera-type eye development; GO:0006725 cellular aromatic compound metabolic process; GO:0060444 branching involved in mammary gland duct morphogenesis; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0032368 regulation of lipid transport; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0061038 uterus morphogenesis; GO:0030154 cell differentiation; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0051049 regulation of transport; GO:0070988 demethylation; GO:0006807 nitrogen compound metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0007338 single fertilization; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0070076 histone lysine demethylation; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0071495 cellular response to endogenous stimulus; GO:0048511 rhythmic process; GO:0044767 single-organism developmental process; GO:0044344 cellular response to fibroblast growth factor stimulus; GO:0044703 multi-organism reproductive process; GO:0010467 gene expression; GO:0031327 negative regulation of cellular biosynthetic process; GO:0071840 cellular component organization or biogenesis; GO:0022612 gland morphogenesis; GO:0065007 biological regulation; GO:0050679 positive regulation of epithelial cell proliferation; ","GO:0043229 intracellular organelle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0003677 DNA binding; GO:0032453 histone demethylase activity (H3-K4 specific); GO:0003714 transcription corepressor activity; GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific); GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific); GO:0043167 ion binding; GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; GO:0005515 protein binding; GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; GO:0008270 zinc ion binding; GO:0003712 transcription cofactor activity; GO:0003700 transcription factor activity, sequence-specific DNA binding; GO:0032451 demethylase activity; GO:0016491 oxidoreductase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0032452 histone demethylase activity; GO:0005488 binding; GO:0051213 dioxygenase activity; GO:0003676 nucleic acid binding; GO:0001071 nucleic acid binding transcription factor activity; GO:0000989 transcription factor activity, transcription factor binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0000988 transcription factor activity, protein binding; ","K11446",null,null,"IPR013637; IPR003347; IPR001965; IPR003349; IPR004198; IPR013083; IPR011011; IPR001606; IPR019787; ","\"Lysine-specific demethylase-like domain; JmjC domain; Zinc finger, PHD-type; JmjN domain; Zinc finger, C5HC2-type; Zinc finger, RING/FYVE/PHD-type; Zinc finger, FYVE/PHD-type; ARID DNA-binding domain; Zinc finger, PHD-finger; \"\r"]
["Q9UGP8","Translocation protein SEC63 homolog OS=Homo sapiens OX=9606 GN=SEC63","SEC63",87.996,9.2214,6.6,4,6,4,0.876,0.957,0.846,1.038,1.217,1.061,1.238,0.0265,"plasma membrane\r","GO:0044700 single organism signaling; GO:0048732 gland development; GO:0072594 establishment of protein localization to organelle; GO:0044699 single-organism process; GO:0015031 protein transport; GO:0030968 endoplasmic reticulum unfolded protein response; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0035966 response to topologically incorrect protein; GO:0007154 cell communication; GO:0070972 protein localization to endoplasmic reticulum; GO:0065002 intracellular protein transmembrane transport; GO:0033365 protein localization to organelle; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0010259 multicellular organism aging; GO:0051716 cellular response to stimulus; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0072657 protein localization to membrane; GO:0071806 protein transmembrane transport; GO:0045047 protein targeting to ER; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:0048513 animal organ development; GO:0001655 urogenital system development; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0007568 aging; GO:0006620 posttranslational protein targeting to membrane; GO:0048856 anatomical structure development; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0033554 cellular response to stress; GO:0046907 intracellular transport; GO:0035967 cellular response to topologically incorrect protein; GO:0034976 response to endoplasmic reticulum stress; GO:0071310 cellular response to organic substance; GO:0072001 renal system development; GO:0036498 IRE1-mediated unfolded protein response; GO:0006613 cotranslational protein targeting to membrane; GO:0050896 response to stimulus; GO:0031204 posttranslational protein targeting to membrane, translocation; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0006886 intracellular protein transport; GO:0061008 hepaticobiliary system development; GO:0007275 multicellular organism development; GO:0034613 cellular protein localization; GO:0090150 establishment of protein localization to membrane; GO:0009987 cellular process; GO:0006986 response to unfolded protein; GO:0006950 response to stress; GO:0034620 cellular response to unfolded protein; GO:0048731 system development; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0010033 response to organic substance; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0055085 transmembrane transport; GO:0001889 liver development; GO:0070727 cellular macromolecule localization; GO:0044767 single-organism developmental process; GO:0051179 localization; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044432 endoplasmic reticulum part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0008565 protein transporter activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0005215 transporter activity; ","K09540","SEC63; translocation protein SEC63","hsa03060 Protein export - Homo sapiens (human); hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); ","IPR004179; IPR014756; IPR001623; IPR000008; ","Sec63 domain; Immunoglobulin E-set; DnaJ domain; C2 domain; \r"]
["Q9UGT4","Sushi domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUSD2","SUSD2",90.207,5.9849,3.3,3,5,3,0.998,0.878,1.155,0.975,0.938,1.059,0.981,0.874,"extracellular\r","GO:0051782 negative regulation of cell division; GO:0050794 regulation of cellular process; GO:1902807 negative regulation of cell cycle G1/S phase transition; GO:0045786 negative regulation of cell cycle; GO:1901988 negative regulation of cell cycle phase transition; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:0006897 endocytosis; GO:0010564 regulation of cell cycle process; GO:0051234 establishment of localization; GO:0006810 transport; GO:0051302 regulation of cell division; GO:0050789 regulation of biological process; GO:0010948 negative regulation of cell cycle process; GO:1901987 regulation of cell cycle phase transition; GO:1902806 regulation of cell cycle G1/S phase transition; GO:0006898 receptor-mediated endocytosis; GO:0006955 immune response; GO:0051179 localization; GO:0051726 regulation of cell cycle; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0030247 polysaccharide binding; GO:0005488 binding; GO:0030246 carbohydrate binding; GO:0038024 cargo receptor activity; GO:0005515 protein binding; GO:0005044 scavenger receptor activity; GO:0001871 pattern binding; ",{"$nulls":3},"IPR000436; IPR001846; IPR005533; IPR001212; ","\"Sushi/SCR/CCP domain; von Willebrand factor, type D domain; AMOP domain; Somatomedin B domain; \"\r"]
["Q9UGV2","Protein NDRG3 OS=Homo sapiens OX=9606 GN=NDRG3","NDRG3",41.408,28.351,9.9,2,2,2,0.927,0.923,1.089,0.914,1.014,1.129,1.04,0.661,"cytoplasm\r","GO:0000003 reproduction; GO:0032502 developmental process; GO:0050794 regulation of cellular process; GO:0045926 negative regulation of growth; GO:0040008 regulation of growth; GO:0048232 male gamete generation; GO:0022414 reproductive process; GO:0007283 spermatogenesis; GO:0048869 cellular developmental process; GO:0019953 sexual reproduction; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0032501 multicellular organismal process; GO:0007276 gamete generation; GO:0051704 multi-organism process; GO:0001558 regulation of cell growth; GO:0030308 negative regulation of cell growth; GO:0032504 multicellular organism reproduction; GO:0030154 cell differentiation; GO:0050789 regulation of biological process; GO:0044767 single-organism developmental process; GO:0044702 single organism reproductive process; GO:0044703 multi-organism reproductive process; GO:0051128 regulation of cellular component organization; GO:0048609 multicellular organismal reproductive process; GO:0009987 cellular process; GO:0065007 biological regulation; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ",{"$nulls":4},"IPR029058; ","Alpha/Beta hydrolase fold; \r"]
["Q9UH62","Armadillo repeat-containing X-linked protein 3 OS=Homo sapiens OX=9606 GN=ARMCX3","ARMCX3",42.5,4.9388,5.5,2,3,2,1.127,0.896,0.964,0.859,1.044,1.111,1.009,0.944,"mitochondria\r","GO:0050794 regulation of cellular process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0009891 positive regulation of biosynthetic process; GO:2001141 regulation of RNA biosynthetic process; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0034613 cellular protein localization; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0010468 regulation of gene expression; GO:0051254 positive regulation of RNA metabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0048522 positive regulation of cellular process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:1903506 regulation of nucleic acid-templated transcription; GO:0070727 cellular macromolecule localization; GO:0050789 regulation of biological process; GO:0031325 positive regulation of cellular metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0019222 regulation of metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0051179 localization; GO:0031328 positive regulation of cellular biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0019867 outer membrane; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0031306 intrinsic component of mitochondrial outer membrane; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0031301 integral component of organelle membrane; GO:0031307 integral component of mitochondrial outer membrane; GO:0044464 cell part; GO:0005622 intracellular; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0031968 organelle outer membrane; GO:0043227 membrane-bounded organelle; GO:0098573 intrinsic component of mitochondrial membrane; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0098588 bounding membrane of organelle; GO:0005741 mitochondrial outer membrane; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0016021 integral component of membrane; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031975 envelope; GO:0032592 integral component of mitochondrial membrane; GO:0031966 mitochondrial membrane; GO:0031300 intrinsic component of organelle membrane; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR006911; IPR011989; IPR016024; ","Armadillo repeat-containing domain; Armadillo-like helical; Armadillo-type fold; \r"]
["Q9UH65","Switch-associated protein 70 OS=Homo sapiens OX=9606 GN=SWAP70","SWAP70",68.997,38.628,20.3,11,12,11,1.037,1.03,1.031,0.954,0.995,0.948,0.935,0.0482,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0030335 positive regulation of cell migration; GO:0065008 regulation of biological quality; GO:0016064 immunoglobulin mediated immune response; GO:0045321 leukocyte activation; GO:0030832 regulation of actin filament length; GO:0044237 cellular metabolic process; GO:0030036 actin cytoskeleton organization; GO:0008152 metabolic process; GO:0032879 regulation of localization; GO:0032535 regulation of cellular component size; GO:0055065 metal ion homeostasis; GO:0050921 positive regulation of chemotaxis; GO:0051493 regulation of cytoskeleton organization; GO:0043170 macromolecule metabolic process; GO:0035305 negative regulation of dephosphorylation; GO:0045190 isotype switching; GO:0051174 regulation of phosphorus metabolic process; GO:0002443 leukocyte mediated immunity; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0002520 immune system development; GO:0051272 positive regulation of cellular component movement; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0006874 cellular calcium ion homeostasis; GO:0032269 negative regulation of cellular protein metabolic process; GO:0044710 single-organism metabolic process; GO:0035304 regulation of protein dephosphorylation; GO:0048583 regulation of response to stimulus; GO:0002381 immunoglobulin production involved in immunoglobulin mediated immune response; GO:0044260 cellular macromolecule metabolic process; GO:1902905 positive regulation of supramolecular fiber organization; GO:0002682 regulation of immune system process; GO:0032233 positive regulation of actin filament bundle assembly; GO:0002685 regulation of leukocyte migration; GO:0030834 regulation of actin filament depolymerization; GO:0097435 supramolecular fiber organization; GO:0002687 positive regulation of leukocyte migration; GO:1902903 regulation of supramolecular fiber organization; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0033632 regulation of cell-cell adhesion mediated by integrin; GO:0007162 negative regulation of cell adhesion; GO:0006259 DNA metabolic process; GO:0016445 somatic diversification of immunoglobulins; GO:0002200 somatic diversification of immune receptors; GO:0032956 regulation of actin cytoskeleton organization; GO:0031399 regulation of protein modification process; GO:0022408 negative regulation of cell-cell adhesion; GO:2000147 positive regulation of cell motility; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0002562 somatic diversification of immune receptors via germline recombination within a single locus; GO:0019724 B cell mediated immunity; GO:0002204 somatic recombination of immunoglobulin genes involved in immune response; GO:0002208 somatic diversification of immunoglobulins involved in immune response; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:2000145 regulation of cell motility; GO:0035308 negative regulation of protein dephosphorylation; GO:0032880 regulation of protein localization; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0002449 lymphocyte mediated immunity; GO:0048878 chemical homeostasis; GO:0002285 lymphocyte activation involved in immune response; GO:0051495 positive regulation of cytoskeleton organization; GO:0051270 regulation of cellular component movement; GO:0032231 regulation of actin filament bundle assembly; GO:0048731 system development; GO:1901879 regulation of protein depolymerization; GO:0030334 regulation of cell migration; GO:0032101 regulation of response to external stimulus; GO:0032970 regulation of actin filament-based process; GO:0002376 immune system process; GO:0060754 positive regulation of mast cell chemotaxis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0002263 cell activation involved in immune response; GO:0030155 regulation of cell adhesion; GO:0061572 actin filament bundle organization; GO:0008064 regulation of actin polymerization or depolymerization; GO:0006873 cellular ion homeostasis; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0001775 cell activation; GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; GO:0007204 positive regulation of cytosolic calcium ion concentration; GO:0048584 positive regulation of response to stimulus; GO:0006955 immune response; GO:0045936 negative regulation of phosphate metabolic process; GO:0072503 cellular divalent inorganic cation homeostasis; GO:0030835 negative regulation of actin filament depolymerization; GO:0040017 positive regulation of locomotion; GO:0051129 negative regulation of cellular component organization; GO:0044699 single-organism process; GO:0031400 negative regulation of protein modification process; GO:0051130 positive regulation of cellular component organization; GO:0022607 cellular component assembly; GO:1902309 negative regulation of peptidyl-serine dephosphorylation; GO:0002250 adaptive immune response; GO:0032103 positive regulation of response to external stimulus; GO:0035303 regulation of dephosphorylation; GO:0006310 DNA recombination; GO:0032502 developmental process; GO:0050801 ion homeostasis; GO:0055074 calcium ion homeostasis; GO:0051494 negative regulation of cytoskeleton organization; GO:0098771 inorganic ion homeostasis; GO:0019725 cellular homeostasis; GO:1901360 organic cyclic compound metabolic process; GO:0002688 regulation of leukocyte chemotaxis; GO:0048522 positive regulation of cellular process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002312 B cell activation involved in immune response; GO:0010639 negative regulation of organelle organization; GO:1902589 single-organism organelle organization; GO:0033629 negative regulation of cell adhesion mediated by integrin; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0002440 production of molecular mediator of immune response; GO:0010638 positive regulation of organelle organization; GO:0043242 negative regulation of protein complex disassembly; GO:1902904 negative regulation of supramolecular fiber organization; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0043244 regulation of protein complex disassembly; GO:0072507 divalent inorganic cation homeostasis; GO:0048856 anatomical structure development; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0030003 cellular cation homeostasis; GO:0051480 regulation of cytosolic calcium ion concentration; GO:0007015 actin filament organization; GO:0044087 regulation of cellular component biogenesis; GO:0051017 actin filament bundle assembly; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0055082 cellular chemical homeostasis; GO:0071704 organic substance metabolic process; GO:1901880 negative regulation of protein depolymerization; GO:0042592 homeostatic process; GO:0002690 positive regulation of leukocyte chemotaxis; GO:0055080 cation homeostasis; GO:0034641 cellular nitrogen compound metabolic process; GO:0009987 cellular process; GO:0042113 B cell activation; GO:0016444 somatic cell DNA recombination; GO:0016447 somatic recombination of immunoglobulin gene segments; GO:0033628 regulation of cell adhesion mediated by integrin; GO:0006807 nitrogen compound metabolic process; GO:0033043 regulation of organelle organization; GO:0046649 lymphocyte activation; GO:1902308 regulation of peptidyl-serine dephosphorylation; GO:0060753 regulation of mast cell chemotaxis; GO:0050920 regulation of chemotaxis; GO:0048518 positive regulation of biological process; GO:0022407 regulation of cell-cell adhesion; GO:0002366 leukocyte activation involved in immune response; GO:0002377 immunoglobulin production; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0010563 negative regulation of phosphorus metabolic process; GO:0002684 positive regulation of immune system process; GO:0051248 negative regulation of protein metabolic process; GO:0090066 regulation of anatomical structure size; GO:0006875 cellular metal ion homeostasis; GO:0051128 regulation of cellular component organization; GO:0040012 regulation of locomotion; GO:0033633 negative regulation of cell-cell adhesion mediated by integrin; GO:0044089 positive regulation of cellular component biogenesis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0031252 cell leading edge; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005886 plasma membrane; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0005856 cytoskeleton; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0030027 lamellipodium; GO:0043227 membrane-bounded organelle; ","GO:0003677 DNA binding; GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0050839 cell adhesion molecule binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0003676 nucleic acid binding; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0005509 calcium ion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K20072",null,null,"IPR011993; IPR011992; IPR002048; IPR001849; ","PH domain-like; EF-hand domain pair; EF-hand domain; Pleckstrin homology domain; \r"]
["Q9UH99","SUN domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUN2","SUN2",80.31,74.351,18.1,9,13,9,0.982,0.996,0.998,0.993,1.001,1.013,1.01,0.25,"nucleus\r","GO:0030048 actin filament-based movement; GO:0065008 regulation of biological quality; GO:0010256 endomembrane system organization; GO:0030335 positive regulation of cell migration; GO:0051674 localization of cell; GO:0022414 reproductive process; GO:0007420 brain development; GO:0040017 positive regulation of locomotion; GO:0007067 mitotic nuclear division; GO:0048869 cellular developmental process; GO:0051647 nucleus localization; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0021987 cerebral cortex development; GO:0040023 establishment of nucleus localization; GO:0051457 maintenance of protein location in nucleus; GO:0051234 establishment of localization; GO:0007097 nuclear migration; GO:0021537 telencephalon development; GO:0072595 maintenance of protein localization in organelle; GO:0010970 transport along microtubule; GO:0051649 establishment of localization in cell; GO:0032879 regulation of localization; GO:0044702 single organism reproductive process; GO:0021885 forebrain cell migration; GO:0021815 modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration; GO:0099515 actin filament-based transport; GO:0060322 head development; GO:0033365 protein localization to organelle; GO:0051651 maintenance of location in cell; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0090292 nuclear matrix anchoring at nuclear membrane; GO:0044765 single-organism transport; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0000278 mitotic cell cycle; GO:0032507 maintenance of protein location in cell; GO:0030473 nuclear migration along microtubule; GO:0061842 microtubule organizing center localization; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0008347 glial cell migration; GO:0048870 cell motility; GO:0051272 positive regulation of cellular component movement; GO:0051321 meiotic cell cycle; GO:0032501 multicellular organismal process; GO:1902582 single-organism intracellular transport; GO:0006810 transport; GO:1902589 single-organism organelle organization; GO:0000226 microtubule cytoskeleton organization; GO:0022029 telencephalon cell migration; GO:0048513 animal organ development; GO:0042063 gliogenesis; GO:0050789 regulation of biological process; GO:0007417 central nervous system development; GO:1902850 microtubule cytoskeleton organization involved in mitosis; GO:0040011 locomotion; GO:0048856 anatomical structure development; GO:0021543 pallium development; GO:0072384 organelle transport along microtubule; GO:0050794 regulation of cellular process; GO:0051640 organelle localization; GO:0000003 reproduction; GO:0044707 single-multicellular organism process; GO:0021799 cerebral cortex radially oriented cell migration; GO:0016477 cell migration; GO:0046907 intracellular transport; GO:0006997 nucleus organization; GO:0016043 cellular component organization; GO:0048285 organelle fission; GO:0043578 nuclear matrix organization; GO:0021795 cerebral cortex cell migration; GO:0007051 spindle organization; GO:2000147 positive regulation of cell motility; GO:1903047 mitotic cell cycle process; GO:0099111 microtubule-based transport; GO:0030705 cytoskeleton-dependent intracellular transport; GO:0006998 nuclear envelope organization; GO:0030154 cell differentiation; GO:1902578 single-organism localization; GO:2000145 regulation of cell motility; GO:0030900 forebrain development; GO:1902580 single-organism cellular localization; GO:0051235 maintenance of location; GO:0007275 multicellular organism development; GO:0007052 mitotic spindle organization; GO:0034613 cellular protein localization; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0045185 maintenance of protein location; GO:0021801 cerebral cortex radial glia guided migration; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0021814 cell motility involved in cerebral cortex radial glia guided migration; GO:0051642 centrosome localization; GO:0044802 single-organism membrane organization; GO:0030334 regulation of cell migration; GO:0051656 establishment of organelle localization; GO:0007017 microtubule-based process; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0007018 microtubule-based movement; GO:0070727 cellular macromolecule localization; GO:0044767 single-organism developmental process; GO:0021817 nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0061024 membrane organization; GO:0000280 nuclear division; GO:0006928 movement of cell or subcellular component; GO:0022402 cell cycle process; GO:0031022 nuclear migration along microfilament; GO:0090286 cytoskeletal anchoring at nuclear membrane; GO:0051179 localization; GO:0040012 regulation of locomotion; GO:0034504 protein localization to nucleus; GO:0022030 telencephalon glial cell migration; GO:0007049 cell cycle; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0000784 nuclear chromosome, telomeric region; GO:0000781 chromosome, telomeric region; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0031224 intrinsic component of membrane; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0000793 condensed chromosome; GO:0031974 membrane-enclosed lumen; GO:0031965 nuclear membrane; GO:0031229 intrinsic component of nuclear inner membrane; GO:0031301 integral component of organelle membrane; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0044454 nuclear chromosome part; GO:0005622 intracellular; GO:0034992 microtubule organizing center attachment site; GO:0044464 cell part; GO:0005639 integral component of nuclear inner membrane; GO:0005694 chromosome; GO:0098805 whole membrane; GO:0019866 organelle inner membrane; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0005637 nuclear inner membrane; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0034993 LINC complex; GO:0097708 intracellular vesicle; GO:0010008 endosome membrane; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005635 nuclear envelope; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0016021 integral component of membrane; GO:0098687 chromosomal region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0031975 envelope; GO:0044453 nuclear membrane part; GO:0000228 nuclear chromosome; GO:0000794 condensed nuclear chromosome; GO:0043234 protein complex; GO:0031300 intrinsic component of organelle membrane; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0008092 cytoskeletal protein binding; GO:0042802 identical protein binding; GO:0008017 microtubule binding; GO:0005521 lamin binding; GO:0005488 binding; GO:0015631 tubulin binding; GO:0005515 protein binding; ","K19347",null,null,"IPR012919; ","SUN domain; \r"]
["Q9UHA4","Ragulator complex protein LAMTOR3 OS=Homo sapiens OX=9606 GN=LAMTOR3","LAMTOR3",13.623,4.3568,8.1,1,3,1,1.044,0.986,0.929,1.05,0.954,1.048,1.031,0.538,"cytoplasm\r","GO:0044700 single organism signaling; GO:0032270 positive regulation of cellular protein metabolic process; GO:0045321 leukocyte activation; GO:0006914 autophagy; GO:0044237 cellular metabolic process; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0008152 metabolic process; GO:0044093 positive regulation of molecular function; GO:0009719 response to endogenous stimulus; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0051347 positive regulation of transferase activity; GO:0008104 protein localization; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0002443 leukocyte mediated immunity; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0031323 regulation of cellular metabolic process; GO:0006810 transport; GO:0000165 MAPK cascade; GO:0010243 response to organonitrogen compound; GO:0051336 regulation of hydrolase activity; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0071230 cellular response to amino acid stimulus; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0050794 regulation of cellular process; GO:0016310 phosphorylation; GO:0002283 neutrophil activation involved in immune response; GO:0031399 regulation of protein modification process; GO:1901700 response to oxygen-containing compound; GO:0044267 cellular protein metabolic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0032147 activation of protein kinase activity; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0071229 cellular response to acid chemical; GO:0051345 positive regulation of hydrolase activity; GO:0051338 regulation of transferase activity; GO:0044248 cellular catabolic process; GO:0034613 cellular protein localization; GO:0009966 regulation of signal transduction; GO:0023014 signal transduction by protein phosphorylation; GO:1902531 regulation of intracellular signal transduction; GO:0043547 positive regulation of GTPase activity; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0002263 cell activation involved in immune response; GO:0045055 regulated exocytosis; GO:0051247 positive regulation of protein metabolic process; GO:0006793 phosphorus metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0001775 cell activation; GO:0043412 macromolecule modification; GO:0048584 positive regulation of response to stimulus; GO:0006955 immune response; GO:0051179 localization; GO:0006887 exocytosis; GO:0001101 response to acid chemical; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0000186 activation of MAPKK activity; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0033036 macromolecule localization; GO:0033674 positive regulation of kinase activity; GO:0051726 regulation of cell cycle; GO:0070887 cellular response to chemical stimulus; GO:0016236 macroautophagy; GO:0002274 myeloid leukocyte activation; GO:0043200 response to amino acid; GO:0045937 positive regulation of phosphate metabolic process; GO:0002446 neutrophil mediated immunity; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0002444 myeloid leukocyte mediated immunity; GO:0071417 cellular response to organonitrogen compound; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:1901699 cellular response to nitrogen compound; GO:0032940 secretion by cell; GO:0043087 regulation of GTPase activity; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0043299 leukocyte degranulation; GO:0019220 regulation of phosphate metabolic process; GO:0036211 protein modification process; GO:0043549 regulation of kinase activity; GO:0045859 regulation of protein kinase activity; GO:0045786 negative regulation of cell cycle; GO:0002252 immune effector process; GO:0043405 regulation of MAP kinase activity; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0032006 regulation of TOR signaling; GO:0006468 protein phosphorylation; GO:0043408 regulation of MAPK cascade; GO:0023056 positive regulation of signaling; GO:0036230 granulocyte activation; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:0035556 intracellular signal transduction; GO:0032008 positive regulation of TOR signaling; GO:0007050 cell cycle arrest; GO:0001932 regulation of protein phosphorylation; GO:0031401 positive regulation of protein modification process; GO:0043312 neutrophil degranulation; GO:0001934 positive regulation of protein phosphorylation; GO:0045860 positive regulation of protein kinase activity; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0043085 positive regulation of catalytic activity; GO:0002366 leukocyte activation involved in immune response; GO:0070727 cellular macromolecule localization; GO:0042119 neutrophil activation; GO:1901701 cellular response to oxygen-containing compound; GO:0071495 cellular response to endogenous stimulus; GO:0051246 regulation of protein metabolic process; GO:0022402 cell cycle process; GO:0009967 positive regulation of signal transduction; GO:0043410 positive regulation of MAPK cascade; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0098857 membrane microdomain; GO:0071986 Ragulator complex; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070821 tertiary granule membrane; GO:0005765 lysosomal membrane; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0044425 membrane part; GO:0031902 late endosome membrane; GO:0005622 intracellular; GO:0044464 cell part; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:0098805 whole membrane; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0098589 membrane region; GO:0005768 endosome; GO:0030055 cell-substrate junction; GO:0030141 secretory granule; GO:0045121 membrane raft; GO:0043227 membrane-bounded organelle; GO:0035579 specific granule membrane; GO:0005924 cell-substrate adherens junction; GO:0000323 lytic vacuole; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0010008 endosome membrane; GO:0098588 bounding membrane of organelle; GO:0005770 late endosome; GO:0070820 tertiary granule; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0098852 lytic vacuole membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0030667 secretory granule membrane; GO:0042581 specific granule; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0019209 kinase activator activity; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0005515 protein binding; GO:0019207 kinase regulator activity; GO:0098772 molecular function regulator; GO:0008047 enzyme activator activity; ","K04370","LAMTOR3; ragulator complex protein LAMTOR3","hsa04010 MAPK signaling pathway - Homo sapiens (human); hsa04150 mTOR signaling pathway - Homo sapiens (human); "]
["Q9UHB6","LIM domain and actin-binding protein 1 OS=Homo sapiens OX=9606 GN=LIMA1","LIMA1",85.225,105.04,24.2,17,19,17,0.934,0.924,0.891,1.069,1.034,1.081,1.158,0.00168,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0065008 regulation of biological quality; GO:0030835 negative regulation of actin filament depolymerization; GO:0032956 regulation of actin cytoskeleton organization; GO:0051129 negative regulation of cellular component organization; GO:0007015 actin filament organization; GO:0044699 single-organism process; GO:0051017 actin filament bundle assembly; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0030832 regulation of actin filament length; GO:1901880 negative regulation of protein depolymerization; GO:0031529 ruffle organization; GO:0030036 actin cytoskeleton organization; GO:0022607 cellular component assembly; GO:0032535 regulation of cellular component size; GO:0051493 regulation of cytoskeleton organization; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0051494 negative regulation of cytoskeleton organization; GO:1901879 regulation of protein depolymerization; GO:0044763 single-organism cellular process; GO:0033043 regulation of organelle organization; GO:0032970 regulation of actin filament-based process; GO:0061572 actin filament bundle organization; GO:1902589 single-organism organelle organization; GO:0010639 negative regulation of organelle organization; GO:0008064 regulation of actin polymerization or depolymerization; GO:0050789 regulation of biological process; GO:0030030 cell projection organization; GO:0006996 organelle organization; GO:0043242 negative regulation of protein complex disassembly; GO:0030029 actin filament-based process; GO:1902904 negative regulation of supramolecular fiber organization; GO:0090066 regulation of anatomical structure size; GO:0043244 regulation of protein complex disassembly; GO:0030834 regulation of actin filament depolymerization; GO:0051128 regulation of cellular component organization; GO:0097435 supramolecular fiber organization; GO:1902903 regulation of supramolecular fiber organization; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0098862 cluster of actin-based cell projections; GO:0005903 brush border; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0032155 cell division site part; GO:0044422 organelle part; GO:0032432 actin filament bundle; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0005925 focal adhesion; GO:0044464 cell part; GO:0005622 intracellular; GO:0005912 adherens junction; GO:0001725 stress fiber; GO:0030055 cell-substrate junction; GO:0032154 cleavage furrow; GO:0042641 actomyosin; GO:0005924 cell-substrate adherens junction; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0097610 cell surface furrow; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0032153 cell division site; GO:0070161 anchoring junction; GO:0097517 contractile actin filament bundle; GO:0015629 actin cytoskeleton; GO:0043226 organelle; GO:0009986 cell surface; ","GO:0051015 actin filament binding; GO:0043167 ion binding; GO:0044877 macromolecular complex binding; GO:0005515 protein binding; GO:0008270 zinc ion binding; GO:0050839 cell adhesion molecule binding; GO:0008092 cytoskeletal protein binding; GO:0046914 transition metal ion binding; GO:0003785 actin monomer binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0003779 actin binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0032403 protein complex binding; ",{"$nulls":3},"IPR001781; ","\"Zinc finger, LIM-type; \"\r"]
["Q9UHB9","Signal recognition particle subunit SRP68 OS=Homo sapiens OX=9606 GN=SRP68","SRP68",70.729,42.903,19.6,11,17,11,0.896,0.974,0.951,1.012,1.075,1.087,1.125,0.0239,"nucleus\r","GO:0046907 intracellular transport; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0072594 establishment of protein localization to organelle; GO:0072657 protein localization to membrane; GO:0071702 organic substance transport; GO:0045047 protein targeting to ER; GO:0006613 cotranslational protein targeting to membrane; GO:0050896 response to stimulus; GO:0015031 protein transport; GO:0051641 cellular localization; GO:0051234 establishment of localization; GO:0045184 establishment of protein localization; GO:0006605 protein targeting; GO:0006810 transport; GO:0006612 protein targeting to membrane; GO:0042493 response to drug; GO:0070727 cellular macromolecule localization; GO:0042221 response to chemical; GO:0051649 establishment of localization in cell; GO:0070972 protein localization to endoplasmic reticulum; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0006886 intracellular protein transport; GO:0033365 protein localization to organelle; GO:0034613 cellular protein localization; GO:0051179 localization; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0090150 establishment of protein localization to membrane; ","GO:0005783 endoplasmic reticulum; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005925 focal adhesion; GO:0005786 signal recognition particle, endoplasmic reticulum targeting; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005840 ribosome; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0048500 signal recognition particle; GO:0070161 anchoring junction; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005048 signal sequence binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0042277 peptide binding; GO:0005047 signal recognition particle binding; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0033218 amide binding; GO:0030942 endoplasmic reticulum signal peptide binding; GO:0043021 ribonucleoprotein complex binding; GO:0008312 7S RNA binding; ","K03107","SRP68; signal recognition particle subunit SRP68","hsa03060 Protein export - Homo sapiens (human); ","IPR011990; ","Tetratricopeptide-like helical domain; \r"]
["Q9UHD2","Serine/threonine-protein kinase TBK1 OS=Homo sapiens OX=9606 GN=TBK1","TBK1",83.641,23.073,3.8,2,2,2,0.983,1.023,1.032,1.021,1.003,0.949,0.979,0.457,"cytoplasm\r","GO:0044700 single organism signaling; GO:0032481 positive regulation of type I interferon production; GO:0010941 regulation of cell death; GO:0032270 positive regulation of cellular protein metabolic process; GO:0044565 dendritic cell proliferation; GO:0045321 leukocyte activation; GO:0042108 positive regulation of cytokine biosynthetic process; GO:0032647 regulation of interferon-alpha production; GO:0098542 defense response to other organism; GO:0009891 positive regulation of biosynthetic process; GO:0031347 regulation of defense response; GO:0044237 cellular metabolic process; GO:0009607 response to biotic stimulus; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0018105 peptidyl-serine phosphorylation; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0044419 interspecies interaction between organisms; GO:0033138 positive regulation of peptidyl-serine phosphorylation; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:0002758 innate immune response-activating signal transduction; GO:0031329 regulation of cellular catabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0031323 regulation of cellular metabolic process; GO:0010506 regulation of autophagy; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0016241 regulation of macroautophagy; GO:1903506 regulation of nucleic acid-templated transcription; GO:0010508 positive regulation of autophagy; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0016239 positive regulation of macroautophagy; GO:0002833 positive regulation of response to biotic stimulus; GO:0006464 cellular protein modification process; GO:0002682 regulation of immune system process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016310 phosphorylation; GO:0044707 single-multicellular organism process; GO:0032606 type I interferon production; GO:0001819 positive regulation of cytokine production; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0048519 negative regulation of biological process; GO:0080134 regulation of response to stress; GO:0051239 regulation of multicellular organismal process; GO:0031349 positive regulation of defense response; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0009896 positive regulation of catabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0009966 regulation of signal transduction; GO:0050778 positive regulation of immune response; GO:0009617 response to bacterium; GO:0002253 activation of immune response; GO:0051254 positive regulation of RNA metabolic process; GO:1902531 regulation of intracellular signal transduction; GO:0006950 response to stress; GO:0032648 regulation of interferon-beta production; GO:0033135 regulation of peptidyl-serine phosphorylation; GO:0043900 regulation of multi-organism process; GO:0032101 regulation of response to external stimulus; GO:0008283 cell proliferation; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0002756 MyD88-independent toll-like receptor signaling pathway; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0051247 positive regulation of protein metabolic process; GO:0032727 positive regulation of interferon-alpha production; GO:0006793 phosphorus metabolic process; GO:0001816 cytokine production; GO:0031325 positive regulation of cellular metabolic process; GO:0001775 cell activation; GO:0007249 I-kappaB kinase/NF-kappaB signaling; GO:0031328 positive regulation of cellular biosynthetic process; GO:0043412 macromolecule modification; GO:0048584 positive regulation of response to stimulus; GO:0006955 immune response; GO:1904415 regulation of xenophagy; GO:0018209 peptidyl-serine modification; GO:0023051 regulation of signaling; GO:0031331 positive regulation of cellular catabolic process; GO:1902533 positive regulation of intracellular signal transduction; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0001818 negative regulation of cytokine production; GO:0006796 phosphate-containing compound metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0045088 regulation of innate immune response; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0032103 positive regulation of response to external stimulus; GO:0002221 pattern recognition receptor signaling pathway; GO:1904417 positive regulation of xenophagy; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0032943 mononuclear cell proliferation; GO:0042035 regulation of cytokine biosynthetic process; GO:0010468 regulation of gene expression; GO:0043902 positive regulation of multi-organism process; GO:0045937 positive regulation of phosphate metabolic process; GO:0031326 regulation of cellular biosynthetic process; GO:0048522 positive regulation of cellular process; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0050830 defense response to Gram-positive bacterium; GO:0010605 negative regulation of macromolecule metabolic process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0051607 defense response to virus; GO:0002224 toll-like receptor signaling pathway; GO:0006954 inflammatory response; GO:0070661 leukocyte proliferation; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0006952 defense response; GO:0036211 protein modification process; GO:0009615 response to virus; GO:0035666 TRIF-dependent toll-like receptor signaling pathway; GO:0002218 activation of innate immune response; GO:0032479 regulation of type I interferon production; GO:0002831 regulation of response to biotic stimulus; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0046651 lymphocyte proliferation; GO:0051707 response to other organism; GO:0045087 innate immune response; GO:0071704 organic substance metabolic process; GO:0006468 protein phosphorylation; GO:0023056 positive regulation of signaling; GO:0016032 viral process; GO:0002757 immune response-activating signal transduction; GO:0010647 positive regulation of cell communication; GO:0045357 regulation of interferon-beta biosynthetic process; GO:0009987 cellular process; GO:1901214 regulation of neuron death; GO:0045089 positive regulation of innate immune response; GO:0006355 regulation of transcription, DNA-templated; GO:0035556 intracellular signal transduction; GO:0042742 defense response to bacterium; GO:0010629 negative regulation of gene expression; GO:0001932 regulation of protein phosphorylation; GO:0031401 positive regulation of protein modification process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0046649 lymphocyte activation; GO:0010556 regulation of macromolecule biosynthetic process; GO:0001934 positive regulation of protein phosphorylation; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0018193 peptidyl-amino acid modification; GO:0032728 positive regulation of interferon-beta production; GO:0051246 regulation of protein metabolic process; GO:0002684 positive regulation of immune system process; GO:0045359 positive regulation of interferon-beta biosynthetic process; GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling; GO:0001817 regulation of cytokine production; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0009967 positive regulation of signal transduction; GO:0032480 negative regulation of type I interferon production; GO:0065007 biological regulation; ","GO:0010008 endosome membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0016020 membrane; GO:0098588 bounding membrane of organelle; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044440 endosomal part; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0004672 protein kinase activity; GO:0051219 phosphoprotein binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016301 kinase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0032550 purine ribonucleoside binding; GO:0004674 protein serine/threonine kinase activity; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K05410","TBK1; TANK-binding kinase 1 [EC:2.7.11.10]","hsa04657 IL-17 signaling pathway - Homo sapiens (human); hsa04620 Toll-like receptor signaling pathway - Homo sapiens (human); hsa05168 Herpes simplex infection - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); hsa05160 Hepatitis C - Homo sapiens (human); hsa05165 Human papillomavirus infection - Homo sapiens (human); hsa04137 Mitophagy - animal - Homo sapiens (human); hsa04014 Ras signaling pathway - Homo sapiens (human); hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human); hsa05167 Kaposi's sarcoma-associated herpesvirus infection - Homo sapiens (human); hsa04623 Cytosolic DNA-sensing pathway - Homo sapiens (human); hsa05162 Measles - Homo sapiens (human); hsa04622 RIG-I-like receptor signaling pathway - Homo sapiens (human); hsa05161 Hepatitis B - Homo sapiens (human); hsa05164 Influenza A - Homo sapiens (human); ","IPR000719; IPR011009; ","Protein kinase domain; Protein kinase-like domain; \r"]
["Q9UHD8","Septin-9 OS=Homo sapiens OX=9606 GN=SEPT9","SEPT9",65.401,129.06,44.2,22,34,22,1.019,1.002,1.001,1.005,1.015,0.993,0.997,0.745,"nucleus\r","GO:0050794 regulation of cellular process; GO:0044085 cellular component biogenesis; GO:0016043 cellular component organization; GO:0060491 regulation of cell projection assembly; GO:0044699 single-organism process; GO:0031344 regulation of cell projection organization; GO:0044087 regulation of cellular component biogenesis; GO:1902115 regulation of organelle assembly; GO:0051259 protein oligomerization; GO:0051130 positive regulation of cellular component organization; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0045724 positive regulation of cilium assembly; GO:1902855 regulation of non-motile cilium assembly; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0071822 protein complex subunit organization; GO:1902017 regulation of cilium assembly; GO:0031346 positive regulation of cell projection organization; GO:0044763 single-organism cellular process; GO:0033043 regulation of organelle organization; GO:0048522 positive regulation of cellular process; GO:0048518 positive regulation of biological process; GO:0043933 macromolecular complex subunit organization; GO:0051291 protein heterooligomerization; GO:0050789 regulation of biological process; GO:0010638 positive regulation of organelle organization; GO:1902117 positive regulation of organelle assembly; GO:1902857 positive regulation of non-motile cilium assembly; GO:0051301 cell division; GO:0051128 regulation of cellular component organization; GO:0070271 protein complex biogenesis; GO:0007049 cell cycle; GO:0044089 positive regulation of cellular component biogenesis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0005938 cell cortex; GO:0005874 microtubule; GO:0071944 cell periphery; GO:0099568 cytoplasmic region; GO:0005737 cytoplasm; GO:0097730 non-motile cilium; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0005623 cell; GO:0099080 supramolecular complex; GO:0032432 actin filament bundle; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0044441 ciliary part; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0032156 septin cytoskeleton; GO:0048471 perinuclear region of cytoplasm; GO:0031105 septin complex; GO:0001725 stress fiber; GO:0042641 actomyosin; GO:0005930 axoneme; GO:0043229 intracellular organelle; GO:0005929 cilium; GO:0099513 polymeric cytoskeletal fiber; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0097014 ciliary plasm; GO:0044446 intracellular organelle part; GO:0097517 contractile actin filament bundle; GO:0044463 cell projection part; GO:0015629 actin cytoskeleton; GO:0099081 supramolecular polymer; GO:0043226 organelle; GO:0044448 cell cortex part; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0050839 cell adhesion molecule binding; GO:0097367 carbohydrate derivative binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0003924 GTPase activity; GO:0045296 cadherin binding; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019001 guanyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0036094 small molecule binding; ","K16938","SEPT3_9_12; septin 3/9/12","hsa05100 Bacterial invasion of epithelial cells - Homo sapiens (human); ","IPR027417; IPR030379; ","P-loop containing nucleoside triphosphate hydrolase; Septin-type guanine nucleotide-binding (G) domain; \r"]
["Q9UHG3","Prenylcysteine oxidase 1 OS=Homo sapiens OX=9606 GN=PCYOX1","PCYOX1",56.639,114.52,30.5,13,29,13,1.123,1.117,1.126,0.854,0.911,0.901,0.792,0.00732,"extracellular\r","GO:0098661 inorganic anion transmembrane transport; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0034220 ion transmembrane transport; GO:0090662 ATP hydrolysis coupled transmembrane transport; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0006821 chloride transport; GO:0044237 cellular metabolic process; GO:0000096 sulfur amino acid metabolic process; GO:0098656 anion transmembrane transport; GO:0071704 organic substance metabolic process; GO:1902476 chloride transmembrane transport; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0006575 cellular modified amino acid metabolic process; GO:0030328 prenylcysteine catabolic process; GO:0044248 cellular catabolic process; GO:0006508 proteolysis; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0099131 ATP hydrolysis coupled ion transmembrane transport; GO:0009987 cellular process; GO:0043632 modification-dependent macromolecule catabolic process; GO:0006790 sulfur compound metabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0019941 modification-dependent protein catabolic process; GO:0098660 inorganic ion transmembrane transport; GO:0044712 single-organism catabolic process; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:0044282 small molecule catabolic process; GO:0044238 primary metabolic process; GO:0030329 prenylcysteine metabolic process; GO:0046395 carboxylic acid catabolic process; GO:0099133 ATP hydrolysis coupled anion transmembrane transport; GO:0006810 transport; GO:0006820 anion transport; GO:1901575 organic substance catabolic process; GO:0055085 transmembrane transport; GO:1901565 organonitrogen compound catabolic process; GO:0000098 sulfur amino acid catabolic process; GO:0042219 cellular modified amino acid catabolic process; GO:0030327 prenylated protein catabolic process; GO:0030163 protein catabolic process; GO:0006811 ion transport; GO:0044710 single-organism metabolic process; GO:0009057 macromolecule catabolic process; GO:0016054 organic acid catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0009063 cellular amino acid catabolic process; GO:0044273 sulfur compound catabolic process; GO:0051179 localization; GO:0006082 organic acid metabolic process; GO:0009056 catabolic process; GO:0015698 inorganic anion transport; GO:0043436 oxoacid metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005615 extracellular space; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0034358 plasma lipoprotein particle; GO:0034385 triglyceride-rich plasma lipoprotein particle; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0034361 very-low-density lipoprotein particle; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0032994 protein-lipid complex; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005764 lysosome; GO:1990777 lipoprotein particle; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0042625 ATPase coupled ion transmembrane transporter activity; GO:0008555 chloride-transporting ATPase activity; GO:0015399 primary active transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0015103 inorganic anion transmembrane transporter activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0016887 ATPase activity; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0043492 ATPase activity, coupled to movement of substances; GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005215 transporter activity; GO:0022804 active transmembrane transporter activity; GO:0015075 ion transmembrane transporter activity; GO:0022853 active ion transmembrane transporter activity; GO:0043225 ATPase-coupled anion transmembrane transporter activity; GO:0017111 nucleoside-triphosphatase activity; GO:0016491 oxidoreductase activity; GO:0015108 chloride transmembrane transporter activity; GO:0001735 prenylcysteine oxidase activity; GO:0015662 ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism; GO:0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity; GO:0042626 ATPase activity, coupled to transmembrane movement of substances; GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor; GO:0042623 ATPase activity, coupled; GO:0016667 oxidoreductase activity, acting on a sulfur group of donors; GO:0008509 anion transmembrane transporter activity; GO:0022857 transmembrane transporter activity; ","K05906","PCYOX1; prenylcysteine oxidase / farnesylcysteine lyase [EC:1.8.3.5 1.8.3.6]","hsa00900 Terpenoid backbone biosynthesis - Homo sapiens (human); ","IPR010795; IPR023753; ","Prenylcysteine lyase; FAD/NAD(P)-binding domain; \r"]
["Q9UHJ6","Sedoheptulokinase OS=Homo sapiens OX=9606 GN=SHPK","SHPK",51.49,9.8063,5.4,2,3,2,0.945,0.87,0.946,1.063,0.997,1.175,1.172,0.0469,"mitochondria\r","GO:0006739 NADP metabolic process; GO:0002694 regulation of leukocyte activation; GO:0019362 pyridine nucleotide metabolic process; GO:0043030 regulation of macrophage activation; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0031347 regulation of defense response; GO:0071345 cellular response to cytokine stimulus; GO:0072524 pyridine-containing compound metabolic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0009607 response to biotic stimulus; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0006098 pentose-phosphate shunt; GO:0070887 cellular response to chemical stimulus; GO:0051716 cellular response to stimulus; GO:0034097 response to cytokine; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0002237 response to molecule of bacterial origin; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0006081 cellular aldehyde metabolic process; GO:0006732 coenzyme metabolic process; GO:0009052 pentose-phosphate shunt, non-oxidative branch; GO:0005975 carbohydrate metabolic process; GO:0071353 cellular response to interleukin-4; GO:0071396 cellular response to lipid; GO:0051704 multi-organism process; GO:0051186 cofactor metabolic process; GO:0042221 response to chemical; GO:0050865 regulation of cell activation; GO:0050789 regulation of biological process; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:0002682 regulation of immune system process; GO:0050794 regulation of cellular process; GO:0035962 response to interleukin-13; GO:0016310 phosphorylation; GO:0071222 cellular response to lipopolysaccharide; GO:0006725 cellular aromatic compound metabolic process; GO:0046496 nicotinamide nucleotide metabolic process; GO:0071310 cellular response to organic substance; GO:1901700 response to oxygen-containing compound; GO:0043207 response to external biotic stimulus; GO:0080134 regulation of response to stress; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0071704 organic substance metabolic process; GO:0033993 response to lipid; GO:0051156 glucose 6-phosphate metabolic process; GO:0071216 cellular response to biotic stimulus; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019682 glyceraldehyde-3-phosphate metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0070670 response to interleukin-4; GO:0009987 cellular process; GO:0009617 response to bacterium; GO:0032496 response to lipopolysaccharide; GO:0006807 nitrogen compound metabolic process; GO:0032101 regulation of response to external stimulus; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0035963 cellular response to interleukin-13; GO:1901701 cellular response to oxygen-containing compound; GO:0006793 phosphorus metabolic process; GO:0071219 cellular response to molecule of bacterial origin; GO:0050727 regulation of inflammatory response; GO:0019637 organophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0044424 intracellular part; GO:0005623 cell; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0050277 sedoheptulokinase activity; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016301 kinase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0016740 transferase activity; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K11214",null,null,"IPR018484; ","\"Carbohydrate kinase, FGGY, N-terminal; \"\r"]
["Q9UHL4","Dipeptidyl peptidase 2 OS=Homo sapiens OX=9606 GN=DPP7","DPP7",54.341,12.886,7.3,3,5,3,1.051,1.213,1.196,1.041,0.736,0.921,0.78,0.0822,"plasma membrane\r","GO:0045321 leukocyte activation; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0006508 proteolysis; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0002274 myeloid leukocyte activation; GO:0002443 leukocyte mediated immunity; GO:0016192 vesicle-mediated transport; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:0043312 neutrophil degranulation; GO:0002263 cell activation involved in immune response; GO:0002444 myeloid leukocyte mediated immunity; GO:0002366 leukocyte activation involved in immune response; GO:0006810 transport; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0032940 secretion by cell; GO:0001775 cell activation; GO:0043299 leukocyte degranulation; GO:0006955 immune response; GO:0051179 localization; GO:0006887 exocytosis; ","GO:0034774 secretory granule lumen; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0042582 azurophil granule; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0008238 exopeptidase activity; GO:0008233 peptidase activity; GO:0017171 serine hydrolase activity; GO:0003824 catalytic activity; GO:0008236 serine-type peptidase activity; GO:0008239 dipeptidyl-peptidase activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0016787 hydrolase activity; GO:0004177 aminopeptidase activity; ","K01276",null,null,"IPR029058; ","Alpha/Beta hydrolase fold; \r"]
["Q9UHQ4","B-cell receptor-associated protein 29 OS=Homo sapiens OX=9606 GN=BCAP29","BCAP29",28.32,13.292,12.4,3,5,3,1.044,1.015,0.924,1.009,1.098,0.921,1.015,0.837,"endoplasmic reticulum\r","GO:0046907 intracellular transport; GO:0001649 osteoblast differentiation; GO:0044707 single-multicellular organism process; GO:0048869 cellular developmental process; GO:0048193 Golgi vesicle transport; GO:0044699 single-organism process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0030154 cell differentiation; GO:0051649 establishment of localization in cell; GO:0070972 protein localization to endoplasmic reticulum; GO:0006915 apoptotic process; GO:0006886 intracellular protein transport; GO:0033365 protein localization to organelle; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0032502 developmental process; GO:0001503 ossification; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0071702 organic substance transport; GO:0032501 multicellular organismal process; GO:0051641 cellular localization; GO:0006810 transport; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0012501 programmed cell death; GO:0051179 localization; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0070973 protein localization to endoplasmic reticulum exit site; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044432 endoplasmic reticulum part; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; "]
["Q9UHQ9","NADH-cytochrome b5 reductase 1 OS=Homo sapiens OX=9606 GN=CYB5R1","CYB5R1",34.094,74.307,45.2,10,16,10,0.932,0.971,0.988,1.052,1.082,0.993,1.082,0.0632,"extracellular\r","GO:1903955 positive regulation of protein targeting to mitochondrion; GO:1903533 regulation of protein targeting; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0010821 regulation of mitochondrion organization; GO:1903749 positive regulation of establishment of protein localization to mitochondrion; GO:0008610 lipid biosynthetic process; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0008152 metabolic process; GO:1903747 regulation of establishment of protein localization to mitochondrion; GO:0032879 regulation of localization; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0006629 lipid metabolic process; GO:0055114 oxidation-reduction process; GO:0044763 single-organism cellular process; GO:0008202 steroid metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:1901617 organic hydroxy compound biosynthetic process; GO:0032386 regulation of intracellular transport; GO:0051050 positive regulation of transport; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0010638 positive regulation of organelle organization; GO:0032940 secretion by cell; GO:0044710 single-organism metabolic process; GO:0051223 regulation of protein transport; GO:1901362 organic cyclic compound biosynthetic process; GO:0051222 positive regulation of protein transport; GO:0050794 regulation of cellular process; GO:0090316 positive regulation of intracellular protein transport; GO:1901615 organic hydroxy compound metabolic process; GO:1903829 positive regulation of cellular protein localization; GO:0002576 platelet degranulation; GO:0016125 sterol metabolic process; GO:0070201 regulation of establishment of protein localization; GO:0060341 regulation of cellular localization; GO:0071704 organic substance metabolic process; GO:0016126 sterol biosynthetic process; GO:1902578 single-organism localization; GO:0015701 bicarbonate transport; GO:0032880 regulation of protein localization; GO:0033157 regulation of intracellular protein transport; GO:0009987 cellular process; GO:0044711 single-organism biosynthetic process; GO:0032388 positive regulation of intracellular transport; GO:0051049 regulation of transport; GO:0016192 vesicle-mediated transport; GO:0033043 regulation of organelle organization; GO:0071702 organic substance transport; GO:1903214 regulation of protein targeting to mitochondrion; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:1901576 organic substance biosynthetic process; GO:0010822 positive regulation of mitochondrion organization; GO:0006694 steroid biosynthetic process; GO:0006820 anion transport; GO:0015711 organic anion transport; GO:0045055 regulated exocytosis; GO:1904951 positive regulation of establishment of protein localization; GO:0006811 ion transport; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:1903827 regulation of cellular protein localization; GO:0065007 biological regulation; GO:0006887 exocytosis; ","GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0031092 platelet alpha granule membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0030667 secretory granule membrane; GO:0044432 endoplasmic reticulum part; GO:0031091 platelet alpha granule; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016651 oxidoreductase activity, acting on NAD(P)H; GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor; GO:0003824 catalytic activity; GO:0005488 binding; GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H; GO:0005515 protein binding; GO:0016491 oxidoreductase activity; ","K00326","E1.6.2.2; cytochrome-b5 reductase [EC:1.6.2.2]","hsa00520 Amino sugar and nucleotide sugar metabolism - Homo sapiens (human); ","IPR017927; IPR001433; IPR008333; IPR017938; IPR001709; ","\"Ferredoxin reductase-type FAD-binding domain; Oxidoreductase FAD/NAD(P)-binding; Oxidoreductase, FAD-binding domain; Riboflavin synthase-like beta-barrel; Flavoprotein pyridine nucleotide cytochrome reductase; \"\r"]
["Q9UHV9","Prefoldin subunit 2 OS=Homo sapiens OX=9606 GN=PFDN2","PFDN2",16.648,45.364,24,3,6,3,0.97,0.995,0.971,1.067,1.005,1.044,1.061,0.0377,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0051130 positive regulation of cellular component organization; GO:0006457 protein folding; GO:0050789 regulation of biological process; GO:0051495 positive regulation of cytoskeleton organization; GO:0010638 positive regulation of organelle organization; GO:0033043 regulation of organelle organization; GO:0048522 positive regulation of cellular process; GO:0051128 regulation of cellular component organization; GO:0051493 regulation of cytoskeleton organization; GO:0048518 positive regulation of biological process; GO:0009987 cellular process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0016272 prefoldin complex; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0051082 unfolded protein binding; GO:0044183 protein binding involved in protein folding; GO:0005488 binding; ","K09549"]
["Q9UHX1","Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60","PUF60",59.875,15.573,8.2,6,8,6,0.899,0.998,0.883,1.063,1.09,1.068,1.159,0.0188,"nucleus\r","GO:0050794 regulation of cellular process; GO:0006725 cellular aromatic compound metabolic process; GO:0097659 nucleic acid-templated transcription; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0000398 mRNA splicing, via spliceosome; GO:0008152 metabolic process; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0006915 apoptotic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0006396 RNA processing; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0006355 regulation of transcription, DNA-templated; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0090304 nucleic acid metabolic process; GO:0008219 cell death; GO:0006351 transcription, DNA-templated; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0010467 gene expression; GO:0012501 programmed cell death; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0030054 cell junction; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031974 membrane-enclosed lumen; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0050839 cell adhesion molecule binding; GO:0003677 DNA binding; GO:0003723 RNA binding; GO:0042802 identical protein binding; GO:1901265 nucleoside phosphate binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0036094 small molecule binding; ","K12838","PUF60; poly(U)-binding-splicing factor PUF60","hsa03040 Spliceosome - Homo sapiens (human); ","IPR034209; IPR000504; IPR034212; IPR012677; IPR034211; IPR003954; ","\"PUF60, RNA recognition motif 1; RNA recognition motif domain; PUF60, RNA recognition motif 3; Nucleotide-binding alpha-beta plait domain; PUF60, RNA recognition motif 2; RNA recognition motif domain, eukaryote; \"\r"]
["Q9UHY1","Nuclear receptor-binding protein OS=Homo sapiens OX=9606 GN=NRBP1","NRBP1",59.844,15.221,7.9,3,4,3,0.985,1.049,1.022,0.941,0.973,1.039,0.966,0.368,"nucleus\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0046907 intracellular transport; GO:0016310 phosphorylation; GO:0006725 cellular aromatic compound metabolic process; GO:0097659 nucleic acid-templated transcription; GO:0006352 DNA-templated transcription, initiation; GO:0044267 cellular protein metabolic process; GO:0048193 Golgi vesicle transport; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0046483 heterocycle metabolic process; GO:0006468 protein phosphorylation; GO:0007154 cell communication; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006367 transcription initiation from RNA polymerase II promoter; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0035556 intracellular signal transduction; GO:0016192 vesicle-mediated transport; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0023052 signaling; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0016070 RNA metabolic process; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0006793 phosphorus metabolic process; GO:0006366 transcription from RNA polymerase II promoter; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0006464 cellular protein modification process; GO:0051179 localization; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:0006888 ER to Golgi vesicle-mediated transport; GO:1901362 organic cyclic compound biosynthetic process; GO:0065007 biological regulation; ","GO:0031252 cell leading edge; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042995 cell projection; GO:0005938 cell cortex; GO:0071944 cell periphery; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0099568 cytoplasmic region; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0030027 lamellipodium; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:0004672 protein kinase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0042802 identical protein binding; GO:0016301 kinase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0042803 protein homodimerization activity; GO:0032555 purine ribonucleotide binding; GO:0004674 protein serine/threonine kinase activity; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K08875",null,null,"IPR000719; IPR001245; IPR011009; ","Protein kinase domain; Serine-threonine/tyrosine-protein kinase catalytic domain; Protein kinase-like domain; \r"]
["Q9UHY7","Enolase-phosphatase E1 OS=Homo sapiens OX=9606 GN=ENOPH1","ENOPH1",28.932,25.525,17.2,4,7,4,1.013,1.053,1.075,0.928,1.009,0.906,0.905,0.0532,"mitochondria\r","GO:0000097 sulfur amino acid biosynthetic process; GO:0016053 organic acid biosynthetic process; GO:0019509 L-methionine salvage from methylthioadenosine; GO:0009066 aspartate family amino acid metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0000096 sulfur amino acid metabolic process; GO:0044272 sulfur compound biosynthetic process; GO:0009086 methionine biosynthetic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0071265 L-methionine biosynthetic process; GO:0006520 cellular amino acid metabolic process; GO:1901607 alpha-amino acid biosynthetic process; GO:0043102 amino acid salvage; GO:0006555 methionine metabolic process; GO:0009987 cellular process; GO:0006790 sulfur compound metabolic process; GO:0009067 aspartate family amino acid biosynthetic process; GO:0008652 cellular amino acid biosynthetic process; GO:0044711 single-organism biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:1901605 alpha-amino acid metabolic process; GO:0044238 primary metabolic process; GO:0016311 dephosphorylation; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0046394 carboxylic acid biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0043094 cellular metabolic compound salvage; GO:0044710 single-organism metabolic process; GO:0044283 small molecule biosynthetic process; GO:0019752 carboxylic acid metabolic process; GO:0071267 L-methionine salvage; GO:0006082 organic acid metabolic process; GO:0043436 oxoacid metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0000287 magnesium ion binding; GO:0042578 phosphoric ester hydrolase activity; GO:0003824 catalytic activity; GO:0016791 phosphatase activity; GO:0005488 binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0043167 ion binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0016787 hydrolase activity; GO:0043874 acireductone synthase activity; ","K09880","mtnC; enolase-phosphatase E1 [EC:3.1.3.77]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00270 Cysteine and methionine metabolism - Homo sapiens (human); ","IPR023214; ","HAD-like domain; \r"]
["Q9UI08","Ena/VASP-like protein OS=Homo sapiens OX=9606 GN=EVL","EVL",44.619,6.8485,8.9,2,2,2,0.644,0.624,0.737,1.461,0.984,1.518,1.977,0.0108,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0030833 regulation of actin filament polymerization; GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0032273 positive regulation of protein polymerization; GO:0060491 regulation of cell projection assembly; GO:0007166 cell surface receptor signaling pathway; GO:0010633 negative regulation of epithelial cell migration; GO:0051129 negative regulation of cellular component organization; GO:0048869 cellular developmental process; GO:0048666 neuron development; GO:0032989 cellular component morphogenesis; GO:0022008 neurogenesis; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0030832 regulation of actin filament length; GO:0051130 positive regulation of cellular component organization; GO:0040013 negative regulation of locomotion; GO:0009605 response to external stimulus; GO:0030036 actin cytoskeleton organization; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0051262 protein tetramerization; GO:0032990 cell part morphogenesis; GO:0065003 macromolecular complex assembly; GO:0032879 regulation of localization; GO:0045010 actin nucleation; GO:0032535 regulation of cellular component size; GO:0048858 cell projection morphogenesis; GO:0032271 regulation of protein polymerization; GO:0031334 positive regulation of protein complex assembly; GO:0051493 regulation of cytoskeleton organization; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0071822 protein complex subunit organization; GO:0010632 regulation of epithelial cell migration; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0008154 actin polymerization or depolymerization; GO:0048812 neuron projection morphogenesis; GO:0023052 signaling; GO:2000146 negative regulation of cell motility; GO:0006935 chemotaxis; GO:0032501 multicellular organismal process; GO:0000902 cell morphogenesis; GO:1902589 single-organism organelle organization; GO:0048513 animal organ development; GO:0042221 response to chemical; GO:0043254 regulation of protein complex assembly; GO:0050789 regulation of biological process; GO:0030030 cell projection organization; GO:0010638 positive regulation of organelle organization; GO:0009887 animal organ morphogenesis; GO:0042330 taxis; GO:1902905 positive regulation of supramolecular fiber organization; GO:0032233 positive regulation of actin filament bundle assembly; GO:0040011 locomotion; GO:0070271 protein complex biogenesis; GO:0097435 supramolecular fiber organization; GO:0048856 anatomical structure development; GO:1902903 regulation of supramolecular fiber organization; GO:0051271 negative regulation of cellular component movement; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0051260 protein homooligomerization; GO:0032956 regulation of actin cytoskeleton organization; GO:0007015 actin filament organization; GO:0031344 regulation of cell projection organization; GO:0044087 regulation of cellular component biogenesis; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0007411 axon guidance; GO:0048468 cell development; GO:0051239 regulation of multicellular organismal process; GO:0051259 protein oligomerization; GO:0000904 cell morphogenesis involved in differentiation; GO:0009653 anatomical structure morphogenesis; GO:0051289 protein homotetramerization; GO:0030154 cell differentiation; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:2000145 regulation of cell motility; GO:0007409 axonogenesis; GO:0031345 negative regulation of cell projection organization; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0051495 positive regulation of cytoskeleton organization; GO:0051270 regulation of cellular component movement; GO:0032231 regulation of actin filament bundle assembly; GO:0048731 system development; GO:0033043 regulation of organelle organization; GO:1900027 regulation of ruffle assembly; GO:0030334 regulation of cell migration; GO:0032970 regulation of actin filament-based process; GO:0031175 neuron projection development; GO:0030838 positive regulation of actin filament polymerization; GO:0048518 positive regulation of biological process; GO:0051492 regulation of stress fiber assembly; GO:0043933 macromolecular complex subunit organization; GO:1900028 negative regulation of ruffle assembly; GO:0030182 neuron differentiation; GO:0061564 axon development; GO:0008064 regulation of actin polymerization or depolymerization; GO:0097485 neuron projection guidance; GO:0030336 negative regulation of cell migration; GO:0044767 single-organism developmental process; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0051496 positive regulation of stress fiber assembly; GO:0006928 movement of cell or subcellular component; GO:0090066 regulation of anatomical structure size; GO:0051128 regulation of cellular component organization; GO:0040012 regulation of locomotion; GO:0044089 positive regulation of cellular component biogenesis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0031252 cell leading edge; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0070161 anchoring junction; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0005856 cytoskeleton; GO:0005925 focal adhesion; GO:0044464 cell part; GO:0005622 intracellular; GO:0030027 lamellipodium; GO:0005912 adherens junction; GO:0030055 cell-substrate junction; GO:0005924 cell-substrate adherens junction; GO:0044444 cytoplasmic part; ","GO:0003779 actin binding; GO:0005522 profilin binding; GO:0019904 protein domain specific binding; GO:0005515 protein binding; GO:0008092 cytoskeletal protein binding; GO:0017124 SH3 domain binding; GO:0005488 binding; ",{"$nulls":3},"IPR014885; IPR011993; IPR000697; ","VASP tetramerisation; PH domain-like; WH1/EVH1 domain; \r"]
["Q9UI12","V-type proton ATPase subunit H OS=Homo sapiens OX=9606 GN=ATP6V1H","ATP6V1H",55.882,44.842,17.8,7,7,7,0.99,1.009,0.957,1.04,0.988,1.068,1.047,0.171,"cytoplasm\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0008286 insulin receptor signaling pathway; GO:0007166 cell surface receptor signaling pathway; GO:0090662 ATP hydrolysis coupled transmembrane transport; GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient; GO:0030641 regulation of cellular pH; GO:0030004 cellular monovalent inorganic cation homeostasis; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0031347 regulation of defense response; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0000041 transition metal ion transport; GO:0007165 signal transduction; GO:0050690 regulation of defense response to virus by virus; GO:1901653 cellular response to peptide; GO:0007154 cell communication; GO:0009719 response to endogenous stimulus; GO:0044419 interspecies interaction between organisms; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0002697 regulation of immune effector process; GO:1901652 response to peptide; GO:0070887 cellular response to chemical stimulus; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0044765 single-organism transport; GO:0051716 cellular response to stimulus; GO:0098655 cation transmembrane transport; GO:0050801 ion homeostasis; GO:0015682 ferric iron transport; GO:0090383 phagosome acidification; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0098771 inorganic ion homeostasis; GO:0044763 single-organism cellular process; GO:0019725 cellular homeostasis; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0031323 regulation of cellular metabolic process; GO:0033572 transferrin transport; GO:0023052 signaling; GO:0010506 regulation of autophagy; GO:0051704 multi-organism process; GO:0016241 regulation of macroautophagy; GO:0006810 transport; GO:0071417 cellular response to organonitrogen compound; GO:0010243 response to organonitrogen compound; GO:0050789 regulation of biological process; GO:0032868 response to insulin; GO:0042221 response to chemical; GO:0043434 response to peptide hormone; GO:1901699 cellular response to nitrogen compound; GO:0050790 regulation of catalytic activity; GO:0032870 cellular response to hormone stimulus; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0032869 cellular response to insulin stimulus; GO:0015991 ATP hydrolysis coupled proton transport; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0002682 regulation of immune system process; GO:0098662 inorganic cation transmembrane transport; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0034220 ion transmembrane transport; GO:0002831 regulation of response to biotic stimulus; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0045851 pH reduction; GO:0006885 regulation of pH; GO:0030001 metal ion transport; GO:0007035 vacuolar acidification; GO:0071310 cellular response to organic substance; GO:0030003 cellular cation homeostasis; GO:1901700 response to oxygen-containing compound; GO:0006826 iron ion transport; GO:0080134 regulation of response to stress; GO:0050896 response to stimulus; GO:0055082 cellular chemical homeostasis; GO:0042592 homeostatic process; GO:0050688 regulation of defense response to virus; GO:1902578 single-organism localization; GO:0006812 cation transport; GO:0055080 cation homeostasis; GO:0016032 viral process; GO:0071375 cellular response to peptide hormone stimulus; GO:1902600 hydrogen ion transmembrane transport; GO:0099132 ATP hydrolysis coupled cation transmembrane transport; GO:0099131 ATP hydrolysis coupled ion transmembrane transport; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0090382 phagosome maturation; GO:0055067 monovalent inorganic cation homeostasis; GO:0098660 inorganic ion transmembrane transport; GO:0043900 regulation of multi-organism process; GO:0016192 vesicle-mediated transport; GO:0050792 regulation of viral process; GO:0032101 regulation of response to external stimulus; GO:0071702 organic substance transport; GO:0010033 response to organic substance; GO:0006897 endocytosis; GO:0006818 hydrogen transport; GO:0015992 proton transport; GO:0045184 establishment of protein localization; GO:0072512 trivalent inorganic cation transport; GO:0055085 transmembrane transport; GO:1901701 cellular response to oxygen-containing compound; GO:0051453 regulation of intracellular pH; GO:0006873 cellular ion homeostasis; GO:0071495 cellular response to endogenous stimulus; GO:0006811 ion transport; GO:0006996 organelle organization; GO:0051452 intracellular pH reduction; GO:0009725 response to hormone; GO:0051179 localization; GO:0015672 monovalent inorganic cation transport; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0033176 proton-transporting V-type ATPase complex; GO:0005623 cell; GO:0044422 organelle part; GO:0005765 lysosomal membrane; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0033180 proton-transporting V-type ATPase, V1 domain; GO:0016471 vacuolar proton-transporting V-type ATPase complex; GO:0005886 plasma membrane; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0016469 proton-transporting two-sector ATPase complex; GO:0044437 vacuolar part; GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0042625 ATPase coupled ion transmembrane transporter activity; GO:0015399 primary active transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism; GO:0015077 monovalent inorganic cation transmembrane transporter activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0015078 hydrogen ion transmembrane transporter activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0016887 ATPase activity; GO:0019829 cation-transporting ATPase activity; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0043492 ATPase activity, coupled to movement of substances; GO:0005488 binding; GO:0036442 hydrogen-exporting ATPase activity; GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; GO:0022890 inorganic cation transmembrane transporter activity; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005215 transporter activity; GO:0022804 active transmembrane transporter activity; GO:0015075 ion transmembrane transporter activity; GO:0022853 active ion transmembrane transporter activity; GO:0017111 nucleoside-triphosphatase activity; GO:0046961 proton-transporting ATPase activity, rotational mechanism; GO:0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity; GO:0030234 enzyme regulator activity; GO:0042626 ATPase activity, coupled to transmembrane movement of substances; GO:0042623 ATPase activity, coupled; GO:0008324 cation transmembrane transporter activity; GO:0022857 transmembrane transporter activity; ","K02144","ATPeV1H; V-type H+-transporting ATPase subunit H","hsa05120 Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human); hsa04142 Lysosome - Homo sapiens (human); hsa05152 Tuberculosis - Homo sapiens (human); hsa05323 Rheumatoid arthritis - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa04150 mTOR signaling pathway - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05110 Vibrio cholerae infection - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); hsa04721 Synaptic vesicle cycle - Homo sapiens (human); ","IPR011987; IPR011989; IPR016024; ","\"ATPase, V1 complex, subunit H, C-terminal; Armadillo-like helical; Armadillo-type fold; \"\r"]
["Q9UI26","Importin-11 OS=Homo sapiens OX=9606 GN=IPO11","IPO11",112.53,12.461,5.6,4,4,4,0.861,1.096,1.063,0.921,1.016,1.048,0.988,0.934,"cyto_nucl\r","GO:0046907 intracellular transport; GO:0072594 establishment of protein localization to organelle; GO:0017038 protein import; GO:1902593 single-organism nuclear import; GO:0044699 single-organism process; GO:0051169 nuclear transport; GO:0071702 organic substance transport; GO:0006610 ribosomal protein import into nucleus; GO:1902582 single-organism intracellular transport; GO:0015031 protein transport; GO:0051641 cellular localization; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006810 transport; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0051649 establishment of localization in cell; GO:1902578 single-organism localization; GO:0051170 nuclear import; GO:0006886 intracellular protein transport; GO:0044744 protein targeting to nucleus; GO:0006913 nucleocytoplasmic transport; GO:1902580 single-organism cellular localization; GO:0033365 protein localization to organelle; GO:0006606 protein import into nucleus; GO:0051179 localization; GO:0034613 cellular protein localization; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0034504 protein localization to nucleus; GO:0044765 single-organism transport; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0044452 nucleolar part; GO:0044424 intracellular part; GO:0005730 nucleolus; GO:0005623 cell; GO:0001650 fibrillar center; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031974 membrane-enclosed lumen; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0031267 small GTPase binding; GO:0008565 protein transporter activity; GO:0017016 Ras GTPase binding; GO:0005488 binding; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0008536 Ran GTPase binding; GO:0051020 GTPase binding; GO:0019899 enzyme binding; GO:0005215 transporter activity; ",{"$nulls":3},"IPR001494; IPR011989; IPR016024; ","\"Importin-beta, N-terminal domain; Armadillo-like helical; Armadillo-type fold; \"\r"]
["Q9UI30","Multifunctional methyltransferase subunit TRM112-like protein OS=Homo sapiens OX=9606 GN=TRMT112","TRMT112",14.199,14.76,21.6,2,3,2,0.794,0.946,0.843,1.098,1.059,1.249,1.319,0.0182,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0006518 peptide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0018364 peptidyl-glutamine methylation; GO:0009451 RNA modification; GO:0044237 cellular metabolic process; GO:0032259 methylation; GO:0043241 protein complex disassembly; GO:0008213 protein alkylation; GO:0008152 metabolic process; GO:0006364 rRNA processing; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0006412 translation; GO:0070475 rRNA base methylation; GO:0016072 rRNA metabolic process; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0036260 RNA capping; GO:0071822 protein complex subunit organization; GO:0043043 peptide biosynthetic process; GO:0031167 rRNA methylation; GO:0044763 single-organism cellular process; GO:0042254 ribosome biogenesis; GO:1901360 organic cyclic compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0016070 RNA metabolic process; GO:0006415 translational termination; GO:0090304 nucleic acid metabolic process; GO:0030488 tRNA methylation; GO:0008033 tRNA processing; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0001510 RNA methylation; GO:0036211 protein modification process; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0070476 rRNA (guanine-N7)-methylation; GO:0044267 cellular protein metabolic process; GO:0000154 rRNA modification; GO:0009452 7-methylguanosine RNA capping; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0006479 protein methylation; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0043624 cellular protein complex disassembly; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0006400 tRNA modification; GO:0009987 cellular process; GO:0036265 RNA (guanine-N7)-methylation; GO:0006807 nitrogen compound metabolic process; GO:0032984 macromolecular complex disassembly; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0006399 tRNA metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0043414 macromolecule methylation; GO:0022411 cellular component disassembly; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0043412 macromolecule modification; GO:0034660 ncRNA metabolic process; GO:0071840 cellular component organization or biogenesis; GO:1901564 organonitrogen compound metabolic process; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0016741 transferase activity, transferring one-carbon groups; GO:0005515 protein binding; GO:0008168 methyltransferase activity; GO:0008276 protein methyltransferase activity; GO:0003824 catalytic activity; GO:0016740 transferase activity; GO:0005488 binding; ","K15448"]
["Q9UI42","Carboxypeptidase A4 OS=Homo sapiens OX=9606 GN=CPA4","CPA4",47.351,12.005,11.4,5,8,5,0.838,0.848,0.799,1.181,1.088,1.134,1.369,0.000461,"extracellular\r","GO:0018393 internal peptidyl-lysine acetylation; GO:0016043 cellular component organization; GO:0006475 internal protein amino acid acetylation; GO:0018394 peptidyl-lysine acetylation; GO:0016570 histone modification; GO:0044267 cellular protein metabolic process; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0018205 peptidyl-lysine modification; GO:0018193 peptidyl-amino acid modification; GO:0008152 metabolic process; GO:0051276 chromosome organization; GO:0016573 histone acetylation; GO:0006473 protein acetylation; GO:0006996 organelle organization; GO:0043543 protein acylation; GO:0044260 cellular macromolecule metabolic process; GO:0006508 proteolysis; GO:0006464 cellular protein modification process; GO:0006325 chromatin organization; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0016569 covalent chromatin modification; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:0009987 cellular process; GO:0071840 cellular component organization or biogenesis; ","GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005576 extracellular region; ","GO:0004180 carboxypeptidase activity; GO:0008233 peptidase activity; GO:0008238 exopeptidase activity; GO:0046914 transition metal ion binding; GO:0004181 metallocarboxypeptidase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0008235 metalloexopeptidase activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0016787 hydrolase activity; GO:0008237 metallopeptidase activity; GO:0008270 zinc ion binding; ","K08637",null,null,"IPR003146; IPR000834; IPR009020; IPR034248; ","\"Carboxypeptidase, activation peptide; Peptidase M14, carboxypeptidase A; Proteinase propeptide inhibitor; Carboxypeptidase A, carboxypeptidase domain; \"\r"]
["Q9UIA9","Exportin-7 OS=Homo sapiens OX=9606 GN=XPO7","XPO7",123.91,40.069,8.9,8,11,8,0.97,1.054,1.023,1.045,1.002,0.987,0.996,0.9,"nucleus\r","GO:0050658 RNA transport; GO:0046907 intracellular transport; GO:0006403 RNA localization; GO:0051028 mRNA transport; GO:0051169 nuclear transport; GO:0051168 nuclear export; GO:0071702 organic substance transport; GO:0006611 protein export from nucleus; GO:0015031 protein transport; GO:0051236 establishment of RNA localization; GO:0051641 cellular localization; GO:0051234 establishment of localization; GO:0006810 transport; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0051649 establishment of localization in cell; GO:0050657 nucleic acid transport; GO:0015931 nucleobase-containing compound transport; GO:0006886 intracellular protein transport; GO:0006913 nucleocytoplasmic transport; GO:0008104 protein localization; GO:0051179 localization; GO:0033036 macromolecule localization; GO:0034613 cellular protein localization; GO:0071705 nitrogen compound transport; ","GO:0043229 intracellular organelle; GO:0005643 nuclear pore; GO:0005635 nuclear envelope; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0012505 endomembrane system; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0031975 envelope; GO:0043227 membrane-bounded organelle; GO:0043234 protein complex; GO:0044428 nuclear part; ","GO:0031267 small GTPase binding; GO:0005487 nucleocytoplasmic transporter activity; GO:0008565 protein transporter activity; GO:0017016 Ras GTPase binding; GO:0005488 binding; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0008536 Ran GTPase binding; GO:0005049 nuclear export signal receptor activity; GO:0051020 GTPase binding; GO:0019899 enzyme binding; GO:0005215 transporter activity; ","K18460",null,null,"IPR001494; IPR016024; ","\"Importin-beta, N-terminal domain; Armadillo-type fold; \"\r"]
["Q9UII2","ATPase inhibitor, mitochondrial OS=Homo sapiens OX=9606 GN=ATPIF1","ATPIF1",12.249,12.764,31.1,5,36,5,1.005,1.02,1.032,1.012,1.049,1.043,1.015,0.324,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:0010941 regulation of cell death; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0002262 myeloid cell homeostasis; GO:1903533 regulation of protein targeting; GO:0010821 regulation of mitochondrion organization; GO:0044237 cellular metabolic process; GO:0008285 negative regulation of cell proliferation; GO:1903364 positive regulation of cellular protein catabolic process; GO:0001525 angiogenesis; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:1901028 regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; GO:0050678 regulation of epithelial cell proliferation; GO:0032879 regulation of localization; GO:1903747 regulation of establishment of protein localization to mitochondrion; GO:0065003 macromolecular complex assembly; GO:0090559 regulation of membrane permeability; GO:1903362 regulation of cellular protein catabolic process; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0051174 regulation of phosphorus metabolic process; GO:1903599 positive regulation of mitophagy; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0002520 immune system development; GO:1904923 regulation of mitophagy in response to mitochondrial depolarization; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0010506 regulation of autophagy; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:0048872 homeostasis of number of cells; GO:0048513 animal organ development; GO:0051336 regulation of hydrolase activity; GO:0010508 positive regulation of autophagy; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:0030218 erythrocyte differentiation; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051223 regulation of protein transport; GO:0033014 tetrapyrrole biosynthetic process; GO:0051899 membrane depolarization; GO:0043068 positive regulation of programmed cell death; GO:1901362 organic cyclic compound biosynthetic process; GO:0006140 regulation of nucleotide metabolic process; GO:0072359 circulatory system development; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0044707 single-multicellular organism process; GO:0007006 mitochondrial membrane organization; GO:0042127 regulation of cell proliferation; GO:0051260 protein homooligomerization; GO:0043067 regulation of programmed cell death; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0060341 regulation of cellular localization; GO:0051259 protein oligomerization; GO:0009653 anatomical structure morphogenesis; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009896 positive regulation of catabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:1901030 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; GO:0042176 regulation of protein catabolic process; GO:0007275 multicellular organism development; GO:0001936 regulation of endothelial cell proliferation; GO:0032880 regulation of protein localization; GO:0009966 regulation of signal transduction; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0006461 protein complex assembly; GO:0006950 response to stress; GO:0044711 single-organism biosynthetic process; GO:0048731 system development; GO:0006779 porphyrin-containing compound biosynthetic process; GO:0002376 immune system process; GO:0072358 cardiovascular system development; GO:0030162 regulation of proteolysis; GO:1901576 organic substance biosynthetic process; GO:0051247 positive regulation of protein metabolic process; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0031325 positive regulation of cellular metabolic process; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:1903827 regulation of cellular protein localization; GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0051188 cofactor biosynthetic process; GO:0046148 pigment biosynthetic process; GO:0001568 blood vessel development; GO:0006839 mitochondrial transport; GO:0023051 regulation of signaling; GO:0048869 cellular developmental process; GO:0031331 positive regulation of cellular catabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0051234 establishment of localization; GO:0001937 negative regulation of endothelial cell proliferation; GO:0051130 positive regulation of cellular component organization; GO:2001233 regulation of apoptotic signaling pathway; GO:0034101 erythrocyte homeostasis; GO:0032780 negative regulation of ATPase activity; GO:0010646 regulation of cell communication; GO:0022607 cellular component assembly; GO:0051262 protein tetramerization; GO:0009893 positive regulation of metabolic process; GO:0007005 mitochondrion organization; GO:0048514 blood vessel morphogenesis; GO:0032502 developmental process; GO:0071822 protein complex subunit organization; GO:0051882 mitochondrial depolarization; GO:1901360 organic cyclic compound metabolic process; GO:0001944 vasculature development; GO:0048522 positive regulation of cellular process; GO:0032386 regulation of intracellular transport; GO:0051050 positive regulation of transport; GO:0010942 positive regulation of cell death; GO:0042391 regulation of membrane potential; GO:0051186 cofactor metabolic process; GO:1902589 single-organism organelle organization; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0010638 positive regulation of organelle organization; GO:0043462 regulation of ATPase activity; GO:0033013 tetrapyrrole metabolic process; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0070271 protein complex biogenesis; GO:0050680 negative regulation of epithelial cell proliferation; GO:0048856 anatomical structure development; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0006783 heme biosynthetic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0043065 positive regulation of apoptotic process; GO:0009118 regulation of nucleoside metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0042168 heme metabolic process; GO:0050896 response to stimulus; GO:0070201 regulation of establishment of protein localization; GO:0051346 negative regulation of hydrolase activity; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:0006778 porphyrin-containing compound metabolic process; GO:0051289 protein homotetramerization; GO:0045862 positive regulation of proteolysis; GO:0046902 regulation of mitochondrial membrane permeability; GO:0072593 reactive oxygen species metabolic process; GO:1904925 positive regulation of mitophagy in response to mitochondrial depolarization; GO:0023056 positive regulation of signaling; GO:2001235 positive regulation of apoptotic signaling pathway; GO:0034641 cellular nitrogen compound metabolic process; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:0033157 regulation of intracellular protein transport; GO:0098780 response to mitochondrial depolarisation; GO:1903578 regulation of ATP metabolic process; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0030099 myeloid cell differentiation; GO:0042440 pigment metabolic process; GO:0051049 regulation of transport; GO:0044802 single-organism membrane organization; GO:0033043 regulation of organelle organization; GO:0006807 nitrogen compound metabolic process; GO:1903214 regulation of protein targeting to mitochondrion; GO:0048518 positive regulation of biological process; GO:0048534 hematopoietic or lymphoid organ development; GO:0030097 hemopoiesis; GO:0044249 cellular biosynthetic process; GO:0010822 positive regulation of mitochondrion organization; GO:0043933 macromolecular complex subunit organization; GO:1900542 regulation of purine nucleotide metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:1903146 regulation of mitophagy; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0045732 positive regulation of protein catabolic process; GO:0009967 positive regulation of signal transduction; GO:0051128 regulation of cellular component organization; GO:0042981 regulation of apoptotic process; GO:0051881 regulation of mitochondrial membrane potential; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0009986 cell surface; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044444 cytoplasmic part; ","GO:0042030 ATPase inhibitor activity; GO:0042802 identical protein binding; GO:0043532 angiostatin binding; GO:0030234 enzyme regulator activity; GO:0051117 ATPase binding; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:0060590 ATPase regulator activity; GO:0004857 enzyme inhibitor activity; GO:0098772 molecular function regulator; GO:0005516 calmodulin binding; GO:0019899 enzyme binding; "]
["Q9UIJ7","GTP:AMP phosphotransferase AK3, mitochondrial OS=Homo sapiens OX=9606 GN=AK3","AK3",25.565,51.415,52.9,12,19,12,1.045,1.034,1.03,0.964,0.939,0.948,0.917,0.0006,"mitochondria\r","GO:0042278 purine nucleoside metabolic process; GO:0009116 nucleoside metabolic process; GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009147 pyrimidine nucleoside triphosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0009611 response to wounding; GO:0008152 metabolic process; GO:0006213 pyrimidine nucleoside metabolic process; GO:1901068 guanosine-containing compound metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0072527 pyrimidine-containing compound metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0046051 UTP metabolic process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0032501 multicellular organismal process; GO:0046131 pyrimidine ribonucleoside metabolic process; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0050817 coagulation; GO:0046039 GTP metabolic process; GO:0016310 phosphorylation; GO:0044707 single-multicellular organism process; GO:0006725 cellular aromatic compound metabolic process; GO:0009208 pyrimidine ribonucleoside triphosphate metabolic process; GO:0009259 ribonucleotide metabolic process; GO:0046041 ITP metabolic process; GO:0050896 response to stimulus; GO:0046033 AMP metabolic process; GO:0007599 hemostasis; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0009987 cellular process; GO:0009119 ribonucleoside metabolic process; GO:0009218 pyrimidine ribonucleotide metabolic process; GO:0050878 regulation of body fluid levels; GO:0006950 response to stress; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0006163 purine nucleotide metabolic process; GO:0046128 purine ribonucleoside metabolic process; GO:0006220 pyrimidine nucleotide metabolic process; GO:0042060 wound healing; GO:0006793 phosphorus metabolic process; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:0065007 biological regulation; GO:1901564 organonitrogen compound metabolic process; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:1901265 nucleoside phosphate binding; GO:0004017 adenylate kinase activity; GO:0019205 nucleobase-containing compound kinase activity; GO:0005515 protein binding; GO:0016776 phosphotransferase activity, phosphate group as acceptor; GO:0019201 nucleotide kinase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0016301 kinase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0046899 nucleoside triphosphate adenylate kinase activity; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0032561 guanyl ribonucleotide binding; GO:0036094 small molecule binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K00944","AK3; nucleoside-triphosphate--adenylate kinase [EC:2.7.4.10]","hsa00230 Purine metabolism - Homo sapiens (human); ","IPR007862; IPR027417; ","\"Adenylate kinase, active site lid domain; P-loop containing nucleoside triphosphate hydrolase; \"\r"]
["Q9UIQ6","Leucyl-cystinyl aminopeptidase OS=Homo sapiens OX=9606 GN=LNPEP","LNPEP",117.35,27.153,9,8,8,8,1.011,1,1.027,1.047,0.981,1.061,1.017,0.56,"cytoplasm\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0006518 peptide metabolic process; GO:0007166 cell surface receptor signaling pathway; GO:0022414 reproductive process; GO:0044699 single-organism process; GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; GO:0044237 cellular metabolic process; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0007154 cell communication; GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0043171 peptide catabolic process; GO:0044706 multi-multicellular organism process; GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0051716 cellular response to stimulus; GO:0048002 antigen processing and presentation of peptide antigen; GO:0044763 single-organism cellular process; GO:0043603 cellular amide metabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:1901575 organic substance catabolic process; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0050789 regulation of biological process; GO:0007267 cell-cell signaling; GO:0030163 protein catabolic process; GO:0060395 SMAD protein signal transduction; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0003013 circulatory system process; GO:0036211 protein modification process; GO:0008217 regulation of blood pressure; GO:0000003 reproduction; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0044267 cellular protein metabolic process; GO:0050896 response to stimulus; GO:0000209 protein polyubiquitination; GO:0071704 organic substance metabolic process; GO:0007565 female pregnancy; GO:0008015 blood circulation; GO:0044248 cellular catabolic process; GO:0006508 proteolysis; GO:0034641 cellular nitrogen compound metabolic process; GO:0009987 cellular process; GO:0003008 system process; GO:0016567 protein ubiquitination; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:0006807 nitrogen compound metabolic process; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:0019882 antigen processing and presentation; GO:1901565 organonitrogen compound catabolic process; GO:0032446 protein modification by small protein conjugation; GO:0044703 multi-organism reproductive process; GO:0009057 macromolecule catabolic process; GO:0061024 membrane organization; GO:0043412 macromolecule modification; GO:0009056 catabolic process; GO:0065007 biological regulation; GO:1901564 organonitrogen compound metabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0031905 early endosome lumen; GO:0005765 lysosomal membrane; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0098805 whole membrane; GO:0005764 lysosome; GO:0048471 perinuclear region of cytoplasm; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0031226 intrinsic component of plasma membrane; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0005829 cytosol; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0031904 endosome lumen; GO:0005886 plasma membrane; GO:0098852 lytic vacuole membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0044444 cytoplasmic part; ","GO:0008238 exopeptidase activity; GO:0008233 peptidase activity; GO:0043167 ion binding; GO:0070006 metalloaminopeptidase activity; GO:0008235 metalloexopeptidase activity; GO:0005515 protein binding; GO:0004177 aminopeptidase activity; GO:0016787 hydrolase activity; GO:0008237 metallopeptidase activity; GO:0033218 amide binding; GO:0008270 zinc ion binding; GO:0046914 transition metal ion binding; GO:0042277 peptide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0046872 metal ion binding; GO:0043169 cation binding; ","K01257","LNPEP; cystinyl aminopeptidase [EC:3.4.11.3]","hsa04614 Renin-angiotensin system - Homo sapiens (human); ","IPR014782; IPR024571; ","\"Peptidase M1, membrane alanine aminopeptidase, N-terminal; ERAP1-like C-terminal domain; \"\r"]
["Q9UIV1","CCR4-NOT transcription complex subunit 7 OS=Homo sapiens OX=9606 GN=CNOT7","CNOT7",32.745,3.8073,3.5,1,1,1,0.951,0.866,0.949,1.083,1.031,1.116,1.168,0.0157,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:1902807 negative regulation of cell cycle G1/S phase transition; GO:0022613 ribonucleoprotein complex biogenesis; GO:0022618 ribonucleoprotein complex assembly; GO:0010608 posttranscriptional regulation of gene expression; GO:0097659 nucleic acid-templated transcription; GO:0009891 positive regulation of biosynthetic process; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0008285 negative regulation of cell proliferation; GO:0072431 signal transduction involved in mitotic G1 DNA damage checkpoint; GO:1902403 signal transduction involved in mitotic DNA integrity checkpoint; GO:0008152 metabolic process; GO:0065003 macromolecular complex assembly; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0043170 macromolecule metabolic process; GO:0090068 positive regulation of cell cycle process; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0044773 mitotic DNA damage checkpoint; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:2000134 negative regulation of G1/S transition of mitotic cell cycle; GO:0045893 positive regulation of transcription, DNA-templated; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0034249 negative regulation of cellular amide metabolic process; GO:0032774 RNA biosynthetic process; GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic; GO:0005975 carbohydrate metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; GO:1903506 regulation of nucleic acid-templated transcription; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0010948 negative regulation of cell cycle process; GO:0072413 signal transduction involved in mitotic cell cycle checkpoint; GO:0031047 gene silencing by RNA; GO:0032269 negative regulation of cellular protein metabolic process; GO:1902400 intracellular signal transduction involved in G1 DNA damage checkpoint; GO:0006402 mRNA catabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0090305 nucleic acid phosphodiester bond hydrolysis; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0007346 regulation of mitotic cell cycle; GO:0042127 regulation of cell proliferation; GO:0017148 negative regulation of translation; GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:1903047 mitotic cell cycle process; GO:0030330 DNA damage response, signal transduction by p53 class mediator; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1902402 signal transduction involved in mitotic DNA damage checkpoint; GO:1901987 regulation of cell cycle phase transition; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0044819 mitotic G1/S transition checkpoint; GO:0009896 positive regulation of catabolic process; GO:0007093 mitotic cell cycle checkpoint; GO:0051171 regulation of nitrogen compound metabolic process; GO:0044248 cellular catabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0061013 regulation of mRNA catabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0045787 positive regulation of cell cycle; GO:0051254 positive regulation of RNA metabolic process; GO:0006950 response to stress; GO:0072331 signal transduction by p53 class mediator; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0006974 cellular response to DNA damage stimulus; GO:0034248 regulation of cellular amide metabolic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0009890 negative regulation of biosynthetic process; GO:1903311 regulation of mRNA metabolic process; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0035195 gene silencing by miRNA; GO:0008284 positive regulation of cell proliferation; GO:2000045 regulation of G1/S transition of mitotic cell cycle; GO:0031331 positive regulation of cellular catabolic process; GO:0035194 posttranscriptional gene silencing by RNA; GO:0044783 G1 DNA damage checkpoint; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:2001141 regulation of RNA biosynthetic process; GO:0045930 negative regulation of mitotic cell cycle; GO:0007165 signal transduction; GO:0000077 DNA damage checkpoint; GO:0044774 mitotic DNA integrity checkpoint; GO:0007154 cell communication; GO:0071826 ribonucleoprotein complex subunit organization; GO:1901991 negative regulation of mitotic cell cycle phase transition; GO:0009893 positive regulation of metabolic process; GO:0022607 cellular component assembly; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA; GO:1902806 regulation of cell cycle G1/S phase transition; GO:0000075 cell cycle checkpoint; GO:1901361 organic cyclic compound catabolic process; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0051726 regulation of cell cycle; GO:0031571 mitotic G1 DNA damage checkpoint; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0031570 DNA integrity checkpoint; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:1903313 positive regulation of mRNA metabolic process; GO:0016070 RNA metabolic process; GO:0006401 RNA catabolic process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; GO:0006351 transcription, DNA-templated; GO:0019222 regulation of metabolic process; GO:0072401 signal transduction involved in DNA integrity checkpoint; GO:0016043 cellular component organization; GO:0045786 negative regulation of cell cycle; GO:0072395 signal transduction involved in cell cycle checkpoint; GO:0006725 cellular aromatic compound metabolic process; GO:1901988 negative regulation of cell cycle phase transition; GO:1900153 positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening; GO:0061014 positive regulation of mRNA catabolic process; GO:0070925 organelle assembly; GO:1900151 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; GO:0042770 signal transduction in response to DNA damage; GO:0034641 cellular nitrogen compound metabolic process; GO:0033962 cytoplasmic mRNA processing body assembly; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0034622 cellular macromolecular complex assembly; GO:0071156 regulation of cell cycle arrest; GO:0044265 cellular macromolecule catabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0072422 signal transduction involved in DNA damage checkpoint; GO:0035556 intracellular signal transduction; GO:0010629 negative regulation of gene expression; GO:0016441 posttranscriptional gene silencing; GO:0006807 nitrogen compound metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0040029 regulation of gene expression, epigenetic; GO:0090501 RNA phosphodiester bond hydrolysis; GO:0016458 gene silencing; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0051246 regulation of protein metabolic process; GO:0006417 regulation of translation; GO:0009057 macromolecule catabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0071158 positive regulation of cell cycle arrest; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0010467 gene expression; GO:0031327 negative regulation of cellular biosynthetic process; GO:0022402 cell cycle process; GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening; GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0065007 biological regulation; GO:0046700 heterocycle catabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0000932 P-body; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0030014 CCR4-NOT complex; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0035770 ribonucleoprotein granule; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0003723 RNA binding; GO:0000175 3'-5'-exoribonuclease activity; GO:0043167 ion binding; GO:0016896 exoribonuclease activity, producing 5'-phosphomonoesters; GO:0008408 3'-5' exonuclease activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0004871 signal transducer activity; GO:0003700 transcription factor activity, sequence-specific DNA binding; GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters; GO:0004535 poly(A)-specific ribonuclease activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0004532 exoribonuclease activity; GO:0001071 nucleic acid binding transcription factor activity; GO:0003676 nucleic acid binding; GO:0004518 nuclease activity; GO:0016788 hydrolase activity, acting on ester bonds; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0004527 exonuclease activity; GO:0004540 ribonuclease activity; ","K12581","CNOT7_8; CCR4-NOT transcription complex subunit 7/8","hsa03018 RNA degradation - Homo sapiens (human); ","IPR012337; ","Ribonuclease H-like domain; \r"]
["Q9UIV8","Serpin B13 OS=Homo sapiens OX=9606 GN=SERPINB13","SERPINB13",44.276,28.733,17.4,6,6,6,0.695,0.64,0.602,1.362,1.395,1.349,2.12,6.07e-05,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0010941 regulation of cell death; GO:0010951 negative regulation of endopeptidase activity; GO:0043069 negative regulation of programmed cell death; GO:0009628 response to abiotic stimulus; GO:1902173 negative regulation of keratinocyte apoptotic process; GO:0060255 regulation of macromolecule metabolic process; GO:0043067 regulation of programmed cell death; GO:1902172 regulation of keratinocyte apoptotic process; GO:0031324 negative regulation of cellular metabolic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0051346 negative regulation of hydrolase activity; GO:1904036 negative regulation of epithelial cell apoptotic process; GO:0010466 negative regulation of peptidase activity; GO:0043066 negative regulation of apoptotic process; GO:0009314 response to radiation; GO:1904035 regulation of epithelial cell apoptotic process; GO:0052548 regulation of endopeptidase activity; GO:0045861 negative regulation of proteolysis; GO:0009416 response to light stimulus; GO:0080090 regulation of primary metabolic process; GO:0030162 regulation of proteolysis; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0009892 negative regulation of metabolic process; GO:0009411 response to UV; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0051246 regulation of protein metabolic process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0065009 regulation of molecular function; GO:0051248 negative regulation of protein metabolic process; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0052547 regulation of peptidase activity; GO:0060548 negative regulation of cell death; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043230 extracellular organelle; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0002020 protease binding; GO:0004867 serine-type endopeptidase inhibitor activity; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0030414 peptidase inhibitor activity; GO:0061134 peptidase regulator activity; GO:0005515 protein binding; GO:0061135 endopeptidase regulator activity; GO:0098772 molecular function regulator; GO:0004857 enzyme inhibitor activity; GO:0004866 endopeptidase inhibitor activity; GO:0019899 enzyme binding; GO:0004869 cysteine-type endopeptidase inhibitor activity; ","K13963","SERPINB; serpin B","hsa05146 Amoebiasis - Homo sapiens (human); ","IPR023796; ","Serpin domain; \r"]
["Q9UJ68","Mitochondrial peptide methionine sulfoxide reductase OS=Homo sapiens OX=9606 GN=MSRA","MSRA",26.132,2.6814,7.2,2,2,2,0.814,0.992,1.051,1.115,0.988,1.042,1.101,0.301,"mitochondria\r","GO:0044267 cellular protein metabolic process; GO:0009066 aspartate family amino acid metabolic process; GO:0044699 single-organism process; GO:0030091 protein repair; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0000096 sulfur amino acid metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0006979 response to oxidative stress; GO:0006555 methionine metabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0009987 cellular process; GO:0006790 sulfur compound metabolic process; GO:0006950 response to stress; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:1901605 alpha-amino acid metabolic process; GO:0044238 primary metabolic process; GO:0044710 single-organism metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0006082 organic acid metabolic process; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:0043436 oxoacid metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0015629 actin cytoskeleton; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0016667 oxidoreductase activity, acting on a sulfur group of donors; GO:0008113 peptide-methionine (S)-S-oxide reductase activity; GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor; GO:0003824 catalytic activity; GO:0016491 oxidoreductase activity; ","K07304",null,null,"IPR002569; ","Peptide methionine sulphoxide reductase MsrA; \r"]
["Q9UJ70","N-acetyl-D-glucosamine kinase OS=Homo sapiens OX=9606 GN=NAGK","NAGK",37.375,121.6,40.1,11,17,11,0.977,1.041,0.987,1.029,0.996,0.975,0.998,0.955,"cytoskeleton\r","GO:0009226 nucleotide-sugar biosynthetic process; GO:1901071 glucosamine-containing compound metabolic process; GO:0016310 phosphorylation; GO:0006725 cellular aromatic compound metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0006050 mannosamine metabolic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0044262 cellular carbohydrate metabolic process; GO:0019262 N-acetylneuraminate catabolic process; GO:0046835 carbohydrate phosphorylation; GO:0046348 amino sugar catabolic process; GO:0044248 cellular catabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009987 cellular process; GO:0006047 UDP-N-acetylglucosamine metabolic process; GO:0018130 heterocycle biosynthetic process; GO:0044712 single-organism catabolic process; GO:0044281 small molecule metabolic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:1901136 carbohydrate derivative catabolic process; GO:0006051 N-acetylmannosamine metabolic process; GO:0044282 small molecule catabolic process; GO:0006048 UDP-N-acetylglucosamine biosynthetic process; GO:0044238 primary metabolic process; GO:0005975 carbohydrate metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0046395 carboxylic acid catabolic process; GO:1901575 organic substance catabolic process; GO:0006044 N-acetylglucosamine metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0016054 organic acid catabolic process; GO:0019752 carboxylic acid metabolic process; GO:0006040 amino sugar metabolic process; GO:0009225 nucleotide-sugar metabolic process; GO:0006054 N-acetylneuraminate metabolic process; GO:0006082 organic acid metabolic process; GO:0009056 catabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0043436 oxoacid metabolic process; GO:0046349 amino sugar biosynthetic process; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0045127 N-acetylglucosamine kinase activity; GO:0009384 N-acylmannosamine kinase activity; GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0019200 carbohydrate kinase activity; GO:0016301 kinase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K00884","NAGK; N-acetylglucosamine kinase [EC:2.7.1.59]","hsa01100 Metabolic pathways - Homo sapiens (human); hsa00520 Amino sugar and nucleotide sugar metabolism - Homo sapiens (human); ","IPR002731; ","\"ATPase, BadF/BadG/BcrA/BcrD type; \"\r"]
["Q9UJ71","C-type lectin domain family 4 member K OS=Homo sapiens OX=9606 GN=CD207","CD207",36.725,35.224,20.7,6,9,6,1.036,1.147,1.06,0.928,1.002,0.869,0.863,0.0451,"plasma membrane\r","GO:0002252 immune effector process; GO:0098542 defense response to other organism; GO:0043207 response to external biotic stimulus; GO:0044764 multi-organism cellular process; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0051234 establishment of localization; GO:0009607 response to biotic stimulus; GO:0009605 response to external stimulus; GO:0016032 viral process; GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I; GO:0006898 receptor-mediated endocytosis; GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; GO:0044419 interspecies interaction between organisms; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0009987 cellular process; GO:0006950 response to stress; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:0048002 antigen processing and presentation of peptide antigen; GO:0016192 vesicle-mediated transport; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0002376 immune system process; GO:0006897 endocytosis; GO:0051704 multi-organism process; GO:0006810 transport; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0019882 antigen processing and presentation; GO:0051607 defense response to virus; GO:0006952 defense response; GO:0051179 localization; GO:0009615 response to virus; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0045334 clathrin-coated endocytic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0030669 clathrin-coated endocytic vesicle membrane; GO:0044433 cytoplasmic vesicle part; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0030662 coated vesicle membrane; GO:0005769 early endosome; GO:0030136 clathrin-coated vesicle; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0098805 whole membrane; GO:0005768 endosome; GO:0031901 early endosome membrane; GO:0030139 endocytic vesicle; GO:0043227 membrane-bounded organelle; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0010008 endosome membrane; GO:0098588 bounding membrane of organelle; GO:0030666 endocytic vesicle membrane; GO:0044446 intracellular organelle part; GO:0044440 endosomal part; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0016021 integral component of membrane; GO:0030135 coated vesicle; GO:0030665 clathrin-coated vesicle membrane; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0044444 cytoplasmic part; ","GO:0030246 carbohydrate binding; GO:0005515 protein binding; GO:0048029 monosaccharide binding; GO:0005488 binding; GO:0005537 mannose binding; GO:0036094 small molecule binding; ","K06561",null,null,"IPR001304; IPR016187; IPR033989; IPR016186; ","\"C-type lectin-like; C-type lectin fold; CD209-like, C-type lectin-like domain; C-type lectin-like/link domain; \"\r"]
["Q9UJ83","2-hydroxyacyl-CoA lyase 1 OS=Homo sapiens OX=9606 GN=HACL1","HACL1",63.728,2.2494,1.6,1,1,1,1.102,1.245,0.993,1.094,0.769,0.835,0.808,0.152,"plasma membrane\r","GO:0044085 cellular component biogenesis; GO:0034440 lipid oxidation; GO:0016043 cellular component organization; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0051259 protein oligomerization; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0022607 cellular component assembly; GO:0030258 lipid modification; GO:0065003 macromolecular complex assembly; GO:0044248 cellular catabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0006629 lipid metabolic process; GO:0016042 lipid catabolic process; GO:0019395 fatty acid oxidation; GO:0071822 protein complex subunit organization; GO:0044712 single-organism catabolic process; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0072329 monocarboxylic acid catabolic process; GO:0044282 small molecule catabolic process; GO:0006631 fatty acid metabolic process; GO:0044238 primary metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0046395 carboxylic acid catabolic process; GO:1901575 organic substance catabolic process; GO:0001561 fatty acid alpha-oxidation; GO:0044710 single-organism metabolic process; GO:0016054 organic acid catabolic process; GO:0019752 carboxylic acid metabolic process; GO:0044242 cellular lipid catabolic process; GO:0006082 organic acid metabolic process; GO:0070271 protein complex biogenesis; GO:0009056 catabolic process; GO:0009062 fatty acid catabolic process; GO:0043436 oxoacid metabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0044439 peroxisomal part; GO:0005777 peroxisome; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0044438 microbody part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031974 membrane-enclosed lumen; GO:0031907 microbody lumen; GO:0070013 intracellular organelle lumen; GO:0005782 peroxisomal matrix; GO:0005622 intracellular; GO:0044464 cell part; GO:0042579 microbody; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; ","GO:0000287 magnesium ion binding; GO:0019842 vitamin binding; GO:0005102 receptor binding; GO:0043167 ion binding; GO:0016829 lyase activity; GO:0005515 protein binding; GO:1901681 sulfur compound binding; GO:0048037 cofactor binding; GO:0030976 thiamine pyrophosphate binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0016830 carbon-carbon lyase activity; GO:0005488 binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0043168 anion binding; GO:0050662 coenzyme binding; GO:0036094 small molecule binding; ","K12261","HACL1; 2-hydroxyacyl-CoA lyase 1 [EC:4.1.-.-]","hsa04146 Peroxisome - Homo sapiens (human); ","IPR012000; IPR029035; IPR029061; IPR012001; IPR011766; ","\"Thiamine pyrophosphate enzyme, central domain; DHS-like NAD/FAD-binding domain; Thiamin diphosphate-binding fold; Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; \"\r"]
["Q9UJS0","Calcium-binding mitochondrial carrier protein Aralar2 OS=Homo sapiens OX=9606 GN=SLC25A13","SLC25A13",74.175,35.176,14.4,8,9,5,0.913,1.031,0.927,1.003,1.078,1.05,1.091,0.115,"cytoplasm\r","GO:0009116 nucleoside metabolic process; GO:0009163 nucleoside biosynthetic process; GO:0046129 purine ribonucleoside biosynthetic process; GO:0044237 cellular metabolic process; GO:0006006 glucose metabolic process; GO:0046390 ribose phosphate biosynthetic process; GO:0008152 metabolic process; GO:0006094 gluconeogenesis; GO:1901137 carbohydrate derivative biosynthetic process; GO:0006091 generation of precursor metabolites and energy; GO:0019693 ribose phosphate metabolic process; GO:0009145 purine nucleoside triphosphate biosynthetic process; GO:0044765 single-organism transport; GO:0018130 heterocycle biosynthetic process; GO:0009206 purine ribonucleoside triphosphate biosynthetic process; GO:0044281 small molecule metabolic process; GO:0006754 ATP biosynthetic process; GO:0044763 single-organism cellular process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0005975 carbohydrate metabolic process; GO:0046942 carboxylic acid transport; GO:0009168 purine ribonucleoside monophosphate biosynthetic process; GO:0090407 organophosphate biosynthetic process; GO:0006810 transport; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0022900 electron transport chain; GO:0009126 purine nucleoside monophosphate metabolic process; GO:0006164 purine nucleotide biosynthetic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0009201 ribonucleoside triphosphate biosynthetic process; GO:0034220 ion transmembrane transport; GO:0009259 ribonucleotide metabolic process; GO:0015807 L-amino acid transport; GO:0046364 monosaccharide biosynthetic process; GO:1902475 L-alpha-amino acid transmembrane transport; GO:0046483 heterocycle metabolic process; GO:1902578 single-organism localization; GO:1903825 organic acid transmembrane transport; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0006865 amino acid transport; GO:0009119 ribonucleoside metabolic process; GO:0044711 single-organism biosynthetic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0042455 ribonucleoside biosynthetic process; GO:1901576 organic substance biosynthetic process; GO:0015849 organic acid transport; GO:0006163 purine nucleotide metabolic process; GO:0089711 L-glutamate transmembrane transport; GO:0055085 transmembrane transport; GO:0006793 phosphorus metabolic process; GO:0006811 ion transport; GO:0044283 small molecule biosynthetic process; GO:0009260 ribonucleotide biosynthetic process; GO:0019637 organophosphate metabolic process; GO:0006835 dicarboxylic acid transport; GO:0051179 localization; GO:0019318 hexose metabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0019319 hexose biosynthetic process; GO:0006839 mitochondrial transport; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0009156 ribonucleoside monophosphate biosynthetic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0006753 nucleoside phosphate metabolic process; GO:0010035 response to inorganic substance; GO:1905039 carboxylic acid transmembrane transport; GO:0055114 oxidation-reduction process; GO:1901360 organic cyclic compound metabolic process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0010038 response to metal ion; GO:0015800 acidic amino acid transport; GO:0042451 purine nucleoside biosynthetic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0042221 response to chemical; GO:0072522 purine-containing compound biosynthetic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:1901657 glycosyl compound metabolic process; GO:0016051 carbohydrate biosynthetic process; GO:0009165 nucleotide biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0009142 nucleoside triphosphate biosynthetic process; GO:0022904 respiratory electron transport chain; GO:0070778 L-aspartate transport; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:0098656 anion transmembrane transport; GO:0071704 organic substance metabolic process; GO:0005996 monosaccharide metabolic process; GO:0051592 response to calcium ion; GO:0034641 cellular nitrogen compound metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0009987 cellular process; GO:0046034 ATP metabolic process; GO:0009124 nucleoside monophosphate biosynthetic process; GO:0043490 malate-aspartate shuttle; GO:0015810 aspartate transport; GO:0009127 purine nucleoside monophosphate biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0089712 L-aspartate transmembrane transport; GO:0003333 amino acid transmembrane transport; GO:0015813 L-glutamate transport; GO:0045333 cellular respiration; GO:0044249 cellular biosynthetic process; GO:0006820 anion transport; GO:0046128 purine ribonucleoside metabolic process; GO:0015711 organic anion transport; GO:0015740 C4-dicarboxylate transport; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0009152 purine ribonucleotide biosynthetic process; GO:1901659 glycosyl compound biosynthetic process; GO:0009150 purine ribonucleotide metabolic process; GO:0071705 nitrogen compound transport; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0031226 intrinsic component of plasma membrane; GO:0044429 mitochondrial part; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0005740 mitochondrial envelope; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0031975 envelope; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0005310 dicarboxylic acid transmembrane transporter activity; GO:0005342 organic acid transmembrane transporter activity; GO:0015179 L-amino acid transmembrane transporter activity; GO:0015075 ion transmembrane transporter activity; GO:0043167 ion binding; GO:0015556 C4-dicarboxylate transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0015172 acidic amino acid transmembrane transporter activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0005313 L-glutamate transmembrane transporter activity; GO:0015183 L-aspartate transmembrane transporter activity; GO:0005488 binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005509 calcium ion binding; GO:0008514 organic anion transmembrane transporter activity; GO:0005215 transporter activity; GO:0008509 anion transmembrane transporter activity; GO:0022857 transmembrane transporter activity; GO:0046943 carboxylic acid transmembrane transporter activity; GO:0015171 amino acid transmembrane transporter activity; ","K15105",null,null,"IPR011992; IPR023395; IPR002048; ","EF-hand domain pair; Mitochondrial carrier domain; EF-hand domain; \r"]
["Q9UJU6","Drebrin-like protein OS=Homo sapiens OX=9606 GN=DBNL","DBNL",48.207,166.22,44.2,16,25,16,0.983,1.022,0.994,1.029,1.012,0.989,1.01,0.562,"nucleus\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0032872 regulation of stress-activated MAPK cascade; GO:0045321 leukocyte activation; GO:0032270 positive regulation of cellular protein metabolic process; GO:0032989 cellular component morphogenesis; GO:0043506 regulation of JUN kinase activity; GO:0044237 cellular metabolic process; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0008152 metabolic process; GO:0065003 macromolecular complex assembly; GO:0044093 positive regulation of molecular function; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0051347 positive regulation of transferase activity; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0007399 nervous system development; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0048812 neuron projection morphogenesis; GO:0007264 small GTPase mediated signal transduction; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0000902 cell morphogenesis; GO:0006810 transport; GO:0071800 podosome assembly; GO:0000165 MAPK cascade; GO:0080135 regulation of cellular response to stress; GO:0032874 positive regulation of stress-activated MAPK cascade; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:0016601 Rac protein signal transduction; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0016310 phosphorylation; GO:0033554 cellular response to stress; GO:0002283 neutrophil activation involved in immune response; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0080134 regulation of response to stress; GO:0071902 positive regulation of protein serine/threonine kinase activity; GO:0009653 anatomical structure morphogenesis; GO:0031529 ruffle organization; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0032147 activation of protein kinase activity; GO:0051338 regulation of transferase activity; GO:0007275 multicellular organism development; GO:0006898 receptor-mediated endocytosis; GO:0009966 regulation of signal transduction; GO:0006461 protein complex assembly; GO:0023014 signal transduction by protein phosphorylation; GO:1902531 regulation of intracellular signal transduction; GO:0006950 response to stress; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0007416 synapse assembly; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:0002263 cell activation involved in immune response; GO:0050808 synapse organization; GO:0030031 cell projection assembly; GO:0030182 neuron differentiation; GO:0045055 regulated exocytosis; GO:0043406 positive regulation of MAP kinase activity; GO:0051247 positive regulation of protein metabolic process; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0001775 cell activation; GO:0051179 localization; GO:0006955 immune response; GO:0048584 positive regulation of response to stimulus; GO:0043412 macromolecule modification; GO:0006887 exocytosis; GO:0046330 positive regulation of JNK cascade; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:0048666 neuron development; GO:1902533 positive regulation of intracellular signal transduction; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0031098 stress-activated protein kinase signaling cascade; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:0070302 regulation of stress-activated protein kinase signaling cascade; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0032990 cell part morphogenesis; GO:0022607 cellular component assembly; GO:0009893 positive regulation of metabolic process; GO:0070304 positive regulation of stress-activated protein kinase signaling cascade; GO:0002250 adaptive immune response; GO:0048858 cell projection morphogenesis; GO:0033674 positive regulation of kinase activity; GO:0046328 regulation of JNK cascade; GO:0002274 myeloid leukocyte activation; GO:0032502 developmental process; GO:0071822 protein complex subunit organization; GO:0045937 positive regulation of phosphate metabolic process; GO:0002446 neutrophil mediated immunity; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0002444 myeloid leukocyte mediated immunity; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0030030 cell projection organization; GO:0032940 secretion by cell; GO:0043507 positive regulation of JUN kinase activity; GO:0007254 JNK cascade; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0043299 leukocyte degranulation; GO:0019220 regulation of phosphate metabolic process; GO:0070271 protein complex biogenesis; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0007265 Ras protein signal transduction; GO:0043549 regulation of kinase activity; GO:0045859 regulation of protein kinase activity; GO:0016043 cellular component organization; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0043405 regulation of MAP kinase activity; GO:0097178 ruffle assembly; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0006468 protein phosphorylation; GO:0070925 organelle assembly; GO:0043408 regulation of MAPK cascade; GO:0023056 positive regulation of signaling; GO:0007257 activation of JUN kinase activity; GO:0036230 granulocyte activation; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:0051403 stress-activated MAPK cascade; GO:0035556 intracellular signal transduction; GO:0001932 regulation of protein phosphorylation; GO:0031401 positive regulation of protein modification process; GO:0043312 neutrophil degranulation; GO:0031175 neuron projection development; GO:0045860 positive regulation of protein kinase activity; GO:0001934 positive regulation of protein phosphorylation; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0043933 macromolecular complex subunit organization; GO:0043085 positive regulation of catalytic activity; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0000187 activation of MAPK activity; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0009967 positive regulation of signal transduction; GO:0043410 positive regulation of MAPK cascade; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0030425 dendrite; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0099568 cytoplasmic region; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0005769 early endosome; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0030136 clathrin-coated vesicle; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0014069 postsynaptic density; GO:0030027 lamellipodium; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043233 organelle lumen; GO:0031252 cell leading edge; GO:0042995 cell projection; GO:0044430 cytoskeletal part; GO:0012506 vesicle membrane; GO:0030135 coated vesicle; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0098794 postsynapse; GO:0043234 protein complex; GO:0099572 postsynaptic specialization; GO:0043230 extracellular organelle; GO:1904724 tertiary granule lumen; GO:0034774 secretory granule lumen; GO:0005938 cell cortex; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0030662 coated vesicle membrane; GO:0032279 asymmetric synapse; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0005768 endosome; GO:0030141 secretory granule; GO:0098984 neuron to neuron synapse; GO:0044456 synapse part; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0070820 tertiary granule; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0002102 podosome; GO:0030665 clathrin-coated vesicle membrane; GO:0015629 actin cytoskeleton; GO:0045202 synapse; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0060205 cytoplasmic vesicle lumen; GO:0001726 ruffle; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:0051015 actin filament binding; GO:0050839 cell adhesion molecule binding; GO:0008092 cytoskeletal protein binding; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0045296 cadherin binding; GO:0044877 macromolecular complex binding; GO:0003779 actin binding; GO:0019904 protein domain specific binding; GO:0008022 protein C-terminus binding; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0008047 enzyme activator activity; GO:0032403 protein complex binding; ","K20520",null,null,"IPR001452; IPR029006; IPR002108; ","SH3 domain; ADF-H/Gelsolin-like domain; Actin-depolymerising factor homology domain; \r"]
["Q9UJW0","Dynactin subunit 4 OS=Homo sapiens OX=9606 GN=DCTN4","DCTN4",52.337,9.9549,5.2,2,3,2,0.924,0.9,0.844,1.114,1.103,1.111,1.247,0.0146,"cytoplasm\r","GO:0051640 organelle localization; GO:0046907 intracellular transport; GO:0016192 vesicle-mediated transport; GO:0048002 antigen processing and presentation of peptide antigen; GO:0051647 nucleus localization; GO:0048193 Golgi vesicle transport; GO:0002376 immune system process; GO:0040023 establishment of nucleus localization; GO:0051656 establishment of organelle localization; GO:0002495 antigen processing and presentation of peptide antigen via MHC class II; GO:0007097 nuclear migration; GO:0051641 cellular localization; GO:0051234 establishment of localization; GO:0006810 transport; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0019882 antigen processing and presentation; GO:0051649 establishment of localization in cell; GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II; GO:0051179 localization; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0006888 ER to Golgi vesicle-mediated transport; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0005869 dynactin complex; GO:0044424 intracellular part; GO:0030286 dynein complex; GO:0005875 microtubule associated complex; GO:0005868 cytoplasmic dynein complex; GO:0005829 cytosol; GO:0005623 cell; GO:0015629 actin cytoskeleton; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0005856 cytoskeleton; GO:0043231 intracellular membrane-bounded organelle; GO:1902494 catalytic complex; GO:0005634 nucleus; GO:0005815 microtubule organizing center; GO:0015630 microtubule cytoskeleton; GO:0005813 centrosome; GO:0005622 intracellular; GO:0044464 cell part; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0047485 protein N-terminus binding; GO:0005488 binding; ","K10426","DCTN4; dynactin 4","hsa05016 Huntington's disease - Homo sapiens (human); hsa04962 Vasopressin-regulated water reabsorption - Homo sapiens (human); "]
["Q9UJY5","ADP-ribosylation factor-binding protein GGA1 OS=Homo sapiens OX=9606 GN=GGA1","GGA1",70.383,5.3986,3.6,3,4,3,0.948,1.052,0.956,1.034,0.991,1.027,1.032,0.411,"cytoplasm\r","GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0060255 regulation of macromolecule metabolic process; GO:0044267 cellular protein metabolic process; GO:1901998 toxin transport; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0071704 organic substance metabolic process; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0009893 positive regulation of metabolic process; GO:0009896 positive regulation of catabolic process; GO:0006886 intracellular protein transport; GO:0042176 regulation of protein catabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0034613 cellular protein localization; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0009987 cellular process; GO:0080090 regulation of primary metabolic process; GO:0016192 vesicle-mediated transport; GO:0009894 regulation of catabolic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:0070727 cellular macromolecule localization; GO:0051247 positive regulation of protein metabolic process; GO:0050789 regulation of biological process; GO:0051246 regulation of protein metabolic process; GO:0061024 membrane organization; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0045732 positive regulation of protein catabolic process; GO:0051179 localization; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0030119 AP-type membrane coat adaptor complex; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005768 endosome; GO:0031901 early endosome membrane; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0010008 endosome membrane; GO:0098588 bounding membrane of organelle; GO:0048475 coated membrane; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0031981 nuclear lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0030131 clathrin adaptor complex; GO:0030118 clathrin coat; GO:0030117 membrane coat; GO:0005794 Golgi apparatus; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0005488 binding; ","K12404","GGA; ADP-ribosylation factor-binding protein GGA","hsa04142 Lysosome - Homo sapiens (human); ","IPR002014; IPR008152; IPR004152; IPR008153; IPR013041; IPR008942; ","\"VHS domain; Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain; GAT domain; Clathrin adaptor, gamma-adaptin, appendage; Coatomer/clathrin adaptor appendage, Ig-like subdomain; ENTH/VHS; \"\r"]
["Q9UJZ1","Stomatin-like protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=STOML2","STOML2",38.534,60.657,25.6,6,9,6,1.034,0.992,0.966,0.96,0.977,1.078,1.008,0.878,"mitochondria\r","GO:0044700 single organism signaling; GO:1900208 regulation of cardiolipin metabolic process; GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0009116 nucleoside metabolic process; GO:0045321 leukocyte activation; GO:0007166 cell surface receptor signaling pathway; GO:0009891 positive regulation of biosynthetic process; GO:0046129 purine ribonucleoside biosynthetic process; GO:0009163 nucleoside biosynthetic process; GO:0090329 regulation of DNA-dependent DNA replication; GO:0019216 regulation of lipid metabolic process; GO:0010821 regulation of mitochondrion organization; GO:0044237 cellular metabolic process; GO:0042110 T cell activation; GO:0046390 ribose phosphate biosynthetic process; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0065003 macromolecular complex assembly; GO:0055065 metal ion homeostasis; GO:0019693 ribose phosphate metabolic process; GO:0010562 positive regulation of phosphorus metabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044801 single-organism membrane fusion; GO:0009145 purine nucleoside triphosphate biosynthetic process; GO:0044765 single-organism transport; GO:0051716 cellular response to stimulus; GO:0051174 regulation of phosphorus metabolic process; GO:0018130 heterocycle biosynthetic process; GO:0009206 purine ribonucleoside triphosphate biosynthetic process; GO:0051054 positive regulation of DNA metabolic process; GO:0080090 regulation of primary metabolic process; GO:0044281 small molecule metabolic process; GO:0006754 ATP biosynthetic process; GO:0044763 single-organism cellular process; GO:0061025 membrane fusion; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0006874 cellular calcium ion homeostasis; GO:0009168 purine ribonucleoside monophosphate biosynthetic process; GO:0050776 regulation of immune response; GO:0006851 mitochondrial calcium ion transport; GO:0090407 organophosphate biosynthetic process; GO:0006810 transport; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0015986 ATP synthesis coupled proton transport; GO:0010604 positive regulation of macromolecule metabolic process; GO:0002682 regulation of immune system process; GO:0009126 purine nucleoside monophosphate metabolic process; GO:0006164 purine nucleotide biosynthetic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0098662 inorganic cation transmembrane transport; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0009201 ribonucleoside triphosphate biosynthetic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0044707 single-multicellular organism process; GO:0046907 intracellular transport; GO:0034220 ion transmembrane transport; GO:0006275 regulation of DNA replication; GO:0042776 mitochondrial ATP synthesis coupled proton transport; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0030001 metal ion transport; GO:0009259 ribonucleotide metabolic process; GO:1903725 regulation of phospholipid metabolic process; GO:0044267 cellular protein metabolic process; GO:0051259 protein oligomerization; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0045740 positive regulation of DNA replication; GO:0051171 regulation of nitrogen compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:1902580 single-organism cellular localization; GO:0045838 positive regulation of membrane potential; GO:0050778 positive regulation of immune response; GO:0046631 alpha-beta T cell activation; GO:0009119 ribonucleoside metabolic process; GO:0006461 protein complex assembly; GO:0048878 chemical homeostasis; GO:1901860 positive regulation of mitochondrial DNA metabolic process; GO:0002253 activation of immune response; GO:0006950 response to stress; GO:0044711 single-organism biosynthetic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901293 nucleoside phosphate biosynthetic process; GO:0048284 organelle fusion; GO:0002376 immune system process; GO:0010876 lipid localization; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0042455 ribonucleoside biosynthetic process; GO:0035710 CD4-positive, alpha-beta T cell activation; GO:1901576 organic substance biosynthetic process; GO:0032623 interleukin-2 production; GO:0006163 purine nucleotide metabolic process; GO:0055085 transmembrane transport; GO:0090297 positive regulation of mitochondrial DNA replication; GO:0006873 cellular ion homeostasis; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0001816 cytokine production; GO:0006811 ion transport; GO:0061024 membrane organization; GO:0031325 positive regulation of cellular metabolic process; GO:0009260 ribonucleotide biosynthetic process; GO:0001775 cell activation; GO:0019637 organophosphate metabolic process; GO:1990046 stress-induced mitochondrial fusion; GO:0048584 positive regulation of response to stimulus; GO:0031328 positive regulation of cellular biosynthetic process; GO:1903727 positive regulation of phospholipid metabolic process; GO:0051179 localization; GO:0015672 monovalent inorganic cation transport; GO:0070838 divalent metal ion transport; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0072503 cellular divalent inorganic cation homeostasis; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0006839 mitochondrial transport; GO:0009117 nucleotide metabolic process; GO:0010918 positive regulation of mitochondrial membrane potential; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0016485 protein processing; GO:0009156 ribonucleoside monophosphate biosynthetic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0022607 cellular component assembly; GO:0090296 regulation of mitochondrial DNA replication; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0007005 mitochondrion organization; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0033036 macromolecule localization; GO:0050851 antigen receptor-mediated signaling pathway; GO:0045937 positive regulation of phosphate metabolic process; GO:0071822 protein complex subunit organization; GO:0098655 cation transmembrane transport; GO:0031326 regulation of cellular biosynthetic process; GO:0050801 ion homeostasis; GO:0055074 calcium ion homeostasis; GO:0098771 inorganic ion homeostasis; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0019725 cellular homeostasis; GO:0015985 energy coupled proton transport, down electrochemical gradient; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0009199 ribonucleoside triphosphate metabolic process; GO:1902582 single-organism intracellular transport; GO:0042451 purine nucleoside biosynthetic process; GO:0042391 regulation of membrane potential; GO:1900210 positive regulation of cardiolipin metabolic process; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0051052 regulation of DNA metabolic process; GO:2000105 positive regulation of DNA-dependent DNA replication; GO:0010638 positive regulation of organelle organization; GO:0072522 purine-containing compound biosynthetic process; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0070271 protein complex biogenesis; GO:0072507 divalent inorganic cation homeostasis; GO:0016043 cellular component organization; GO:0072511 divalent inorganic cation transport; GO:0009165 nucleotide biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0009142 nucleoside triphosphate biosynthetic process; GO:0030003 cellular cation homeostasis; GO:0050896 response to stimulus; GO:1901566 organonitrogen compound biosynthetic process; GO:0055082 cellular chemical homeostasis; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0006816 calcium ion transport; GO:0055080 cation homeostasis; GO:0006812 cation transport; GO:1901858 regulation of mitochondrial DNA metabolic process; GO:1990542 mitochondrial transmembrane transport; GO:0008053 mitochondrial fusion; GO:0002757 immune response-activating signal transduction; GO:1902600 hydrogen ion transmembrane transport; GO:0006508 proteolysis; GO:0034641 cellular nitrogen compound metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0009987 cellular process; GO:0034982 mitochondrial protein processing; GO:0046034 ATP metabolic process; GO:0009124 nucleoside monophosphate biosynthetic process; GO:0098660 inorganic ion transmembrane transport; GO:0009127 purine nucleoside monophosphate biosynthetic process; GO:0044802 single-organism membrane organization; GO:0033043 regulation of organelle organization; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0046649 lymphocyte activation; GO:0048518 positive regulation of biological process; GO:0045834 positive regulation of lipid metabolic process; GO:0015992 proton transport; GO:0006818 hydrogen transport; GO:0044249 cellular biosynthetic process; GO:0010822 positive regulation of mitochondrion organization; GO:0043933 macromolecular complex subunit organization; GO:0051641 cellular localization; GO:0046128 purine ribonucleoside metabolic process; GO:0050852 T cell receptor signaling pathway; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0009152 purine ribonucleotide biosynthetic process; GO:1901659 glycosyl compound biosynthetic process; GO:0002684 positive regulation of immune system process; GO:0010467 gene expression; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0006875 cellular metal ion homeostasis; GO:0051128 regulation of cellular component organization; GO:0009150 purine ribonucleotide metabolic process; GO:0051604 protein maturation; GO:0051881 regulation of mitochondrial membrane potential; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0019898 extrinsic component of membrane; GO:0098857 membrane microdomain; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005740 mitochondrial envelope; GO:0005856 cytoskeleton; GO:0070013 intracellular organelle lumen; GO:0031970 organelle envelope lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0019866 organelle inner membrane; GO:0098589 membrane region; GO:0045121 membrane raft; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0019897 extrinsic component of plasma membrane; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044459 plasma membrane part; GO:0005758 mitochondrial intermembrane space; GO:0031975 envelope; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:1901612 cardiolipin binding; GO:0005102 receptor binding; GO:0005488 binding; GO:0005543 phospholipid binding; GO:0043167 ion binding; GO:0008289 lipid binding; GO:0005515 protein binding; GO:0043168 anion binding; GO:0051020 GTPase binding; GO:0019899 enzyme binding; GO:1901611 phosphatidylglycerol binding; ",{"$nulls":3},"IPR032435; IPR001107; ","\"Band 7, C-terminal extension; Band 7 domain; \"\r"]
["Q9UK22","F-box only protein 2 OS=Homo sapiens OX=9606 GN=FBXO2","FBXO2",33.327,37.766,20.6,4,7,4,1.153,1.041,1.014,0.89,1.041,0.867,0.872,0.116,"cytoplasm\r","GO:0044699 single-organism process; GO:0036503 ERAD pathway; GO:0044237 cellular metabolic process; GO:0008285 negative regulation of cell proliferation; GO:0031396 regulation of protein ubiquitination; GO:0008152 metabolic process; GO:0030433 ubiquitin-dependent ERAD pathway; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0009100 glycoprotein metabolic process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0031323 regulation of cellular metabolic process; GO:1901575 organic substance catabolic process; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0044710 single-organism metabolic process; GO:0030163 protein catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006464 cellular protein modification process; GO:0036211 protein modification process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0042127 regulation of cell proliferation; GO:0034976 response to endoplasmic reticulum stress; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:0060255 regulation of macromolecule metabolic process; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:0010498 proteasomal protein catabolic process; GO:0071704 organic substance metabolic process; GO:0000209 protein polyubiquitination; GO:1901135 carbohydrate derivative metabolic process; GO:0044248 cellular catabolic process; GO:0006508 proteolysis; GO:0009987 cellular process; GO:0043632 modification-dependent macromolecule catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0006516 glycoprotein catabolic process; GO:0016567 protein ubiquitination; GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; GO:0006950 response to stress; GO:0019941 modification-dependent protein catabolic process; GO:0044712 single-organism catabolic process; GO:1901136 carbohydrate derivative catabolic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0032446 protein modification by small protein conjugation; GO:0051246 regulation of protein metabolic process; GO:0009057 macromolecule catabolic process; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0043412 macromolecule modification; GO:0009056 catabolic process; GO:0065007 biological regulation; ","GO:0030425 dendrite; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0019005 SCF ubiquitin ligase complex; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0043197 dendritic spine; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:1902494 catalytic complex; GO:0044309 neuron spine; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043005 neuron projection; GO:0000151 ubiquitin ligase complex; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0044456 synapse part; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0031461 cullin-RING ubiquitin ligase complex; GO:0012505 endomembrane system; GO:1990234 transferase complex; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0005576 extracellular region; GO:0045202 synapse; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0036477 somatodendritic compartment; GO:0098794 postsynapse; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0001540 beta-amyloid binding; GO:0097367 carbohydrate derivative binding; GO:0019787 ubiquitin-like protein transferase activity; GO:0003824 catalytic activity; GO:0042277 peptide binding; GO:0005488 binding; GO:0004842 ubiquitin-protein transferase activity; GO:0030246 carbohydrate binding; GO:0005515 protein binding; GO:0033218 amide binding; GO:0001948 glycoprotein binding; GO:0016740 transferase activity; ","K10099","FBXO2; F-box protein 2","hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human); hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); ","IPR001810; IPR007397; IPR008979; ","F-box domain; F-box associated (FBA) domain; Galactose-binding domain-like; \r"]
["Q9UK41","Vacuolar protein sorting-associated protein 28 homolog OS=Homo sapiens OX=9606 GN=VPS28","VPS28",25.425,39.327,27.1,5,7,5,0.97,0.914,0.946,1.101,0.979,1.014,1.093,0.0855,"cytoplasm\r","GO:0060627 regulation of vesicle-mediated transport; GO:0044085 cellular component biogenesis; GO:0010256 endomembrane system organization; GO:0072594 establishment of protein localization to organelle; GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; GO:1902581 multi-organism cellular localization; GO:0006623 protein targeting to vacuole; GO:0044764 multi-organism cellular process; GO:0006914 autophagy; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0031400 negative regulation of protein modification process; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0006605 protein targeting; GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway; GO:0031396 regulation of protein ubiquitination; GO:1902583 multi-organism intracellular transport; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0009893 positive regulation of metabolic process; GO:0022607 cellular component assembly; GO:0072666 establishment of protein localization to vacuole; GO:0032879 regulation of localization; GO:0036258 multivesicular body assembly; GO:0033365 protein localization to organelle; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0075733 intracellular transport of virus; GO:0044419 interspecies interaction between organisms; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0016236 macroautophagy; GO:0080090 regulation of primary metabolic process; GO:0009894 regulation of catabolic process; GO:0039702 viral budding via host ESCRT complex; GO:0048522 positive regulation of cellular process; GO:0036257 multivesicular body organization; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051704 multi-organism process; GO:0051050 positive regulation of transport; GO:0016197 endosomal transport; GO:0072665 protein localization to vacuole; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0030163 protein catabolic process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0051223 regulation of protein transport; GO:0051222 positive regulation of protein transport; GO:0050794 regulation of cellular process; GO:1902579 multi-organism localization; GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0019068 virion assembly; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:0045807 positive regulation of endocytosis; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0032509 endosome transport via multivesicular body sorting pathway; GO:1902592 multi-organism membrane budding; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0070201 regulation of establishment of protein localization; GO:0071704 organic substance metabolic process; GO:0070925 organelle assembly; GO:0016032 viral process; GO:0045324 late endosome to vacuole transport; GO:0009896 positive regulation of catabolic process; GO:0006886 intracellular protein transport; GO:0044248 cellular catabolic process; GO:0006508 proteolysis; GO:0032880 regulation of protein localization; GO:0042176 regulation of protein catabolic process; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; GO:0031397 negative regulation of protein ubiquitination; GO:0043632 modification-dependent macromolecule catabolic process; GO:2000395 regulation of ubiquitin-dependent endocytosis; GO:0044265 cellular macromolecule catabolic process; GO:0030100 regulation of endocytosis; GO:0046794 transport of virus; GO:0044803 multi-organism membrane organization; GO:0019941 modification-dependent protein catabolic process; GO:0051049 regulation of transport; GO:0016192 vesicle-mediated transport; GO:0016050 vesicle organization; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:1902590 multi-organism organelle organization; GO:0009892 negative regulation of metabolic process; GO:0051641 cellular localization; GO:0044766 multi-organism transport; GO:1903321 negative regulation of protein modification by small protein conjugation or removal; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0051247 positive regulation of protein metabolic process; GO:1904951 positive regulation of establishment of protein localization; GO:0046755 viral budding; GO:0006996 organelle organization; GO:0007034 vacuolar transport; GO:0051246 regulation of protein metabolic process; GO:0061024 membrane organization; GO:0006900 membrane budding; GO:0009057 macromolecule catabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0051128 regulation of cellular component organization; GO:0045732 positive regulation of protein catabolic process; GO:0051179 localization; GO:0007032 endosome organization; GO:0009056 catabolic process; GO:2000397 positive regulation of ubiquitin-dependent endocytosis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0070062 extracellular exosome; GO:0036452 ESCRT complex; GO:0031902 late endosome membrane; GO:0000813 ESCRT I complex; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0010008 endosome membrane; GO:0005770 late endosome; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0043130 ubiquitin binding; GO:0005515 protein binding; GO:0032182 ubiquitin-like protein binding; GO:0005488 binding; GO:0032403 protein complex binding; GO:0044877 macromolecular complex binding; ","K12184","VPS28; ESCRT-I complex subunit VPS28","hsa04144 Endocytosis - Homo sapiens (human); ","IPR017899; IPR017898; ","\"Vacuolar protein sorting-associated, VPS28, C-terminal; Vacuolar protein sorting-associated, VPS28, N-terminal; \"\r"]
["Q9UK55","Protein Z-dependent protease inhibitor OS=Homo sapiens OX=9606 GN=SERPINA10","SERPINA10",50.706,9.9066,3.6,1,1,1,0.954,1.03,0.962,0.977,1.011,1.07,1.038,0.359,"extracellular\r","GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0007596 blood coagulation; GO:0065008 regulation of biological quality; GO:0010951 negative regulation of endopeptidase activity; GO:0060255 regulation of macromolecule metabolic process; GO:0044699 single-organism process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0007599 hemostasis; GO:0051346 negative regulation of hydrolase activity; GO:0009611 response to wounding; GO:0010466 negative regulation of peptidase activity; GO:0008152 metabolic process; GO:0009987 cellular process; GO:0052548 regulation of endopeptidase activity; GO:0045861 negative regulation of proteolysis; GO:0050878 regulation of body fluid levels; GO:0006950 response to stress; GO:0080090 regulation of primary metabolic process; GO:0030162 regulation of proteolysis; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0009892 negative regulation of metabolic process; GO:0008218 bioluminescence; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0042060 wound healing; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0051246 regulation of protein metabolic process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0065009 regulation of molecular function; GO:0051248 negative regulation of protein metabolic process; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0050817 coagulation; GO:0052547 regulation of peptidase activity; GO:0065007 biological regulation; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:0043167 ion binding; GO:0061134 peptidase regulator activity; GO:0008201 heparin binding; GO:0098772 molecular function regulator; GO:0004857 enzyme inhibitor activity; GO:1901681 sulfur compound binding; GO:0004866 endopeptidase inhibitor activity; GO:0004867 serine-type endopeptidase inhibitor activity; GO:0097367 carbohydrate derivative binding; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0030414 peptidase inhibitor activity; GO:0061135 endopeptidase regulator activity; GO:0043168 anion binding; GO:0005539 glycosaminoglycan binding; ","K04525",null,null,"IPR023796; IPR033835; ","Serpin domain; Protein Z-dependent peptidase inhibitor; \r"]
["Q9UK76","Jupiter microtubule associated homolog 1 OS=Homo sapiens OX=9606 GN=JPT1","JPT1",16.014,5.7482,11.7,1,1,1,0.787,0.791,0.821,1.158,1.126,1.297,1.493,0.000916,"nucleus\r",null,"GO:0016020 membrane; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0031090 organelle membrane; GO:0005635 nuclear envelope; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005730 nucleolus; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031965 nuclear membrane; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0031975 envelope; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; "]
["Q9UKF7","Cytoplasmic phosphatidylinositol transfer protein 1 OS=Homo sapiens OX=9606 GN=PITPNC1","PITPNC1",38.387,2.1788,2.4,1,1,1,1.169,0.919,0.952,0.933,0.862,1.173,0.976,0.832,"nucleus\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0051716 cellular response to stimulus; GO:0006869 lipid transport; GO:0044699 single-organism process; GO:0071702 organic substance transport; GO:0010876 lipid localization; GO:0015914 phospholipid transport; GO:0023052 signaling; GO:0050896 response to stimulus; GO:0051234 establishment of localization; GO:0006820 anion transport; GO:0006810 transport; GO:0015748 organophosphate ester transport; GO:0015711 organic anion transport; GO:0007165 signal transduction; GO:0050789 regulation of biological process; GO:1902578 single-organism localization; GO:0007154 cell communication; GO:0006811 ion transport; GO:0033036 macromolecule localization; GO:0051179 localization; GO:0009987 cellular process; GO:0044765 single-organism transport; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0070300 phosphatidic acid binding; GO:0005488 binding; GO:0035091 phosphatidylinositol binding; GO:0005543 phospholipid binding; GO:0043167 ion binding; GO:0005319 lipid transporter activity; GO:0008289 lipid binding; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0043168 anion binding; GO:0008526 phosphatidylinositol transporter activity; GO:1901611 phosphatidylglycerol binding; GO:0005215 transporter activity; GO:0005548 phospholipid transporter activity; ",{"$nulls":3},"IPR023393; ","START-like domain; \r"]
["Q9UKG1","DCC-interacting protein 13-alpha OS=Homo sapiens OX=9606 GN=APPL1","APPL1",79.663,45.738,13,9,10,9,1.046,1.035,1.03,0.965,0.968,0.985,0.938,0.00122,"nucleus\r","GO:0038034 signal transduction in absence of ligand; GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0008286 insulin receptor signaling pathway; GO:0097191 extrinsic apoptotic signaling pathway; GO:0097190 apoptotic signaling pathway; GO:0007166 cell surface receptor signaling pathway; GO:1903076 regulation of protein localization to plasma membrane; GO:0071310 cellular response to organic substance; GO:1901700 response to oxygen-containing compound; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0070201 regulation of establishment of protein localization; GO:0060341 regulation of cellular localization; GO:1903729 regulation of plasma membrane organization; GO:1904375 regulation of protein localization to cell periphery; GO:1905475 regulation of protein localization to membrane; GO:0007165 signal transduction; GO:1901653 cellular response to peptide; GO:0007154 cell communication; GO:0032879 regulation of localization; GO:0071375 cellular response to peptide hormone stimulus; GO:0006915 apoptotic process; GO:0009719 response to endogenous stimulus; GO:0032880 regulation of protein localization; GO:0010827 regulation of glucose transport; GO:0090003 regulation of establishment of protein localization to plasma membrane; GO:1901652 response to peptide; GO:0009987 cellular process; GO:0046324 regulation of glucose import; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0070887 cellular response to chemical stimulus; GO:0051716 cellular response to stimulus; GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand; GO:0051049 regulation of transport; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0008283 cell proliferation; GO:0010033 response to organic substance; GO:0023052 signaling; GO:0071417 cellular response to organonitrogen compound; GO:0010243 response to organonitrogen compound; GO:0042221 response to chemical; GO:0032868 response to insulin; GO:1901701 cellular response to oxygen-containing compound; GO:0050789 regulation of biological process; GO:0043434 response to peptide hormone; GO:1901699 cellular response to nitrogen compound; GO:0008219 cell death; GO:0071495 cellular response to endogenous stimulus; GO:0032870 cellular response to hormone stimulus; GO:1901698 response to nitrogen compound; GO:0032869 cellular response to insulin stimulus; GO:0051128 regulation of cellular component organization; GO:0012501 programmed cell death; GO:0009725 response to hormone; GO:0007049 cell cycle; GO:1903827 regulation of cellular protein localization; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0031901 early endosome membrane; GO:0043227 membrane-bounded organelle; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0010008 endosome membrane; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0012506 vesicle membrane; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0043422 protein kinase B binding; GO:0005515 protein binding; GO:0042802 identical protein binding; GO:0019900 kinase binding; GO:0019899 enzyme binding; GO:0005488 binding; GO:0019901 protein kinase binding; ","K08733","APPL1; DCC-interacting protein 13 alpha","hsa05200 Pathways in cancer - Homo sapiens (human); hsa05210 Colorectal cancer - Homo sapiens (human); hsa04211 Longevity regulating pathway - Homo sapiens (human); ","IPR027267; IPR011993; IPR006020; IPR001849; ","Arfaptin homology (AH) domain/BAR domain; PH domain-like; PTB/PI domain; Pleckstrin homology domain; \r"]
["Q9UKG9","Peroxisomal carnitine O-octanoyltransferase OS=Homo sapiens OX=9606 GN=CROT","CROT",70.178,9.3419,5.4,3,3,3,1.025,0.947,0.846,1.049,1.054,1.083,1.131,0.0904,"cytoplasm\r","GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0015718 monocarboxylic acid transport; GO:0034032 purine nucleoside bisphosphate metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0030258 lipid modification; GO:0019693 ribose phosphate metabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0033036 macromolecule localization; GO:0044765 single-organism transport; GO:0006629 lipid metabolic process; GO:0019395 fatty acid oxidation; GO:0006869 lipid transport; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0072521 purine-containing compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0072329 monocarboxylic acid catabolic process; GO:0006732 coenzyme metabolic process; GO:0046942 carboxylic acid transport; GO:0006577 amino-acid betaine metabolic process; GO:0051186 cofactor metabolic process; GO:0006810 transport; GO:0046395 carboxylic acid catabolic process; GO:1901575 organic substance catabolic process; GO:0044710 single-organism metabolic process; GO:0009437 carnitine metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0006082 organic acid metabolic process; GO:0009062 fatty acid catabolic process; GO:0043436 oxoacid metabolic process; GO:0034440 lipid oxidation; GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase; GO:0006725 cellular aromatic compound metabolic process; GO:0009259 ribonucleotide metabolic process; GO:0097164 ammonium ion metabolic process; GO:0071704 organic substance metabolic process; GO:0015908 fatty acid transport; GO:1902578 single-organism localization; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0044248 cellular catabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0051791 medium-chain fatty acid metabolic process; GO:0009987 cellular process; GO:0009119 ribonucleoside metabolic process; GO:0016042 lipid catabolic process; GO:0033865 nucleoside bisphosphate metabolic process; GO:0015936 coenzyme A metabolic process; GO:0044712 single-organism catabolic process; GO:0006635 fatty acid beta-oxidation; GO:0033875 ribonucleoside bisphosphate metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0010876 lipid localization; GO:0044282 small molecule catabolic process; GO:0006631 fatty acid metabolic process; GO:0044238 primary metabolic process; GO:0015849 organic acid transport; GO:0006163 purine nucleotide metabolic process; GO:0006820 anion transport; GO:0046128 purine ribonucleoside metabolic process; GO:0015711 organic anion transport; GO:0006793 phosphorus metabolic process; GO:0006811 ion transport; GO:0016054 organic acid catabolic process; GO:0019752 carboxylic acid metabolic process; GO:0044242 cellular lipid catabolic process; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0051179 localization; GO:0009056 catabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0043229 intracellular organelle; GO:0044439 peroxisomal part; GO:0005777 peroxisome; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0044438 microbody part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031907 microbody lumen; GO:0070013 intracellular organelle lumen; GO:0005782 peroxisomal matrix; GO:0005622 intracellular; GO:0044464 cell part; GO:0042579 microbody; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; ","GO:0016746 transferase activity, transferring acyl groups; GO:0008458 carnitine O-octanoyltransferase activity; GO:0016406 carnitine O-acyltransferase activity; GO:0005102 receptor binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016414 O-octanoyltransferase activity; GO:0005515 protein binding; GO:0016415 octanoyltransferase activity; GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups; GO:0016740 transferase activity; GO:0008374 O-acyltransferase activity; ","K05940","CROT; carnitine O-octanoyltransferase [EC:2.3.1.137]","hsa04146 Peroxisome - Homo sapiens (human); "]
["Q9UKK3","Poly [ADP-ribose] polymerase 4 OS=Homo sapiens OX=9606 GN=PARP4","PARP4",192.59,6.2629,2.3,4,5,4,0.931,0.972,0.976,1.052,1.047,1.026,1.085,0.00832,"peroxisome\r","GO:0043413 macromolecule glycosylation; GO:0033554 cellular response to stress; GO:0006725 cellular aromatic compound metabolic process; GO:0006259 DNA metabolic process; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:0071704 organic substance metabolic process; GO:0042493 response to drug; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0070085 glycosylation; GO:0051716 cellular response to stimulus; GO:0006486 protein glycosylation; GO:0009101 glycoprotein biosynthetic process; GO:0006950 response to stress; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0009100 glycoprotein metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0006974 cellular response to DNA damage stimulus; GO:0044249 cellular biosynthetic process; GO:0006471 protein ADP-ribosylation; GO:0006810 transport; GO:0006281 DNA repair; GO:0042221 response to chemical; GO:0090304 nucleic acid metabolic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0008219 cell death; GO:0044710 single-organism metabolic process; GO:0006954 inflammatory response; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0006952 defense response; GO:0051179 localization; GO:0043412 macromolecule modification; GO:0036211 protein modification process; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005874 microtubule; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005856 cytoskeleton; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0005829 cytosol; GO:0005819 spindle; GO:0005576 extracellular region; GO:0099081 supramolecular polymer; GO:0005876 spindle microtubule; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0016763 transferase activity, transferring pentosyl groups; GO:0003677 DNA binding; GO:0003950 NAD+ ADP-ribosyltransferase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0016757 transferase activity, transferring glycosyl groups; GO:0016740 transferase activity; GO:0019899 enzyme binding; ","K10798","PARP; poly [ADP-ribose] polymerase [EC:2.4.2.30]","hsa04210 Apoptosis - Homo sapiens (human); hsa04217 Necroptosis - Homo sapiens (human); hsa03410 Base excision repair - Homo sapiens (human); hsa04064 NF-kappa B signaling pathway - Homo sapiens (human); ","IPR004102; IPR013694; IPR012317; IPR002035; IPR001357; ","\"Poly(ADP-ribose) polymerase, regulatory domain; VIT domain; Poly(ADP-ribose) polymerase, catalytic domain; von Willebrand factor, type A; BRCT domain; \"\r"]
["Q9UKK9","ADP-sugar pyrophosphatase OS=Homo sapiens OX=9606 GN=NUDT5","NUDT5",24.327,45.513,34.2,7,11,7,0.923,0.953,0.938,1.002,1.09,1.009,1.102,0.0277,"nucleus\r","GO:0046365 monosaccharide catabolic process; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009185 ribonucleoside diphosphate metabolic process; GO:1990966 ATP generation from poly-ADP-D-ribose; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0008152 metabolic process; GO:1901292 nucleoside phosphate catabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0009134 nucleoside diphosphate catabolic process; GO:1901361 organic cyclic compound catabolic process; GO:0019693 ribose phosphate metabolic process; GO:0043170 macromolecule metabolic process; GO:0019321 pentose metabolic process; GO:0006014 D-ribose metabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0005975 carbohydrate metabolic process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0016052 carbohydrate catabolic process; GO:0019439 aromatic compound catabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:1901575 organic substance catabolic process; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0009126 purine nucleoside monophosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0006325 chromatin organization; GO:0016043 cellular component organization; GO:0006338 chromatin remodeling; GO:0006725 cellular aromatic compound metabolic process; GO:0046434 organophosphate catabolic process; GO:0009259 ribonucleotide metabolic process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0005996 monosaccharide metabolic process; GO:0044248 cellular catabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0009191 ribonucleoside diphosphate catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0009987 cellular process; GO:0009119 ribonucleoside metabolic process; GO:0009132 nucleoside diphosphate metabolic process; GO:0046034 ATP metabolic process; GO:0044724 single-organism carbohydrate catabolic process; GO:0044712 single-organism catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0019303 D-ribose catabolic process; GO:0044282 small molecule catabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0034656 nucleobase-containing small molecule catabolic process; GO:0044238 primary metabolic process; GO:0006163 purine nucleotide metabolic process; GO:0019323 pentose catabolic process; GO:0046128 purine ribonucleoside metabolic process; GO:0051276 chromosome organization; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0009056 catabolic process; GO:0046700 heterocycle catabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0071840 cellular component organization or biogenesis; GO:0009123 nucleoside monophosphate metabolic process; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0000287 magnesium ion binding; GO:0003723 RNA binding; GO:0046983 protein dimerization activity; GO:0043167 ion binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0019144 ADP-sugar diphosphatase activity; GO:0016787 hydrolase activity; GO:0017110 nucleoside-diphosphatase activity; GO:0030515 snoRNA binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0044715 8-oxo-dGDP phosphatase activity; GO:0042802 identical protein binding; GO:0016462 pyrophosphatase activity; GO:0016779 nucleotidyltransferase activity; GO:0003824 catalytic activity; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0047631 ADP-ribose diphosphatase activity; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0016740 transferase activity; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K13987","NUDT5; ADP-sugar pyrophosphatase / 8-oxo-dGDP phosphatase / ADP-D-ribose pyrophosphorylase [EC:3.6.1.13 3.6.1.58 3.6.1.- 2.7.7.96]","hsa00230 Purine metabolism - Homo sapiens (human); ","IPR015797; IPR020476; IPR000086; ","NUDIX hydrolase domain-like; NUDIX hydrolase; NUDIX hydrolase domain; \r"]
["Q9UKM9","RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY","RALY",32.463,20.388,15.7,5,10,5,0.879,0.918,0.876,1.088,1.101,1.131,1.242,0.000336,"nucleus\r","GO:0050794 regulation of cellular process; GO:0065008 regulation of biological quality; GO:0006725 cellular aromatic compound metabolic process; GO:0097659 nucleic acid-templated transcription; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0009058 biosynthetic process; GO:0032844 regulation of homeostatic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0000398 mRNA splicing, via spliceosome; GO:0008152 metabolic process; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:2000188 regulation of cholesterol homeostasis; GO:0006396 RNA processing; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0006355 regulation of transcription, DNA-templated; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:0031323 regulation of cellular metabolic process; GO:1901576 organic substance biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0010467 gene expression; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005681 spliceosomal complex; GO:0005623 cell; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:1902494 catalytic complex; GO:0005622 intracellular; GO:0044464 cell part; GO:0071013 catalytic step 2 spliceosome; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:1901265 nucleoside phosphate binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0003712 transcription cofactor activity; GO:0000988 transcription factor activity, protein binding; GO:0036094 small molecule binding; ","K12895",null,null,"IPR000504; IPR012677; ","RNA recognition motif domain; Nucleotide-binding alpha-beta plait domain; \r"]
["Q9UKR3","Kallikrein-13 OS=Homo sapiens OX=9606 GN=KLK13","KLK13",30.57,4.9723,9.4,3,3,3,0.503,0.473,0.423,1.488,1.561,1.493,3.247,2.2e-05,"extracellular\r","GO:0044707 single-multicellular organism process; GO:0031424 keratinization; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0016485 protein processing; GO:0071704 organic substance metabolic process; GO:0009913 epidermal cell differentiation; GO:0008152 metabolic process; GO:0030154 cell differentiation; GO:0008544 epidermis development; GO:0006508 proteolysis; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0043588 skin development; GO:0009888 tissue development; GO:0030216 keratinocyte differentiation; GO:0048731 system development; GO:0070268 cornification; GO:0044763 single-organism cellular process; GO:0044238 primary metabolic process; GO:0032501 multicellular organismal process; GO:0048513 animal organ development; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0010467 gene expression; GO:0012501 programmed cell death; GO:0051604 protein maturation; GO:0048856 anatomical structure development; GO:0030855 epithelial cell differentiation; ","GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0004252 serine-type endopeptidase activity; GO:0004175 endopeptidase activity; GO:0008233 peptidase activity; GO:0003824 catalytic activity; GO:0017171 serine hydrolase activity; GO:0005488 binding; GO:0008236 serine-type peptidase activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0005515 protein binding; GO:0016787 hydrolase activity; ","K09463",null,null,"IPR009003; IPR001254; ","\"Peptidase S1, PA clan; Serine proteases, trypsin domain; \"\r"]
["Q9UKR5","Probable ergosterol biosynthetic protein 28 OS=Homo sapiens OX=9606 GN=ERG28","ERG28",15.864,1.9435,5.7,1,1,1,1.093,1.043,1.002,1.033,0.986,0.863,0.918,0.216,"plasma membrane\r","GO:0016129 phytosteroid biosynthetic process; GO:1901615 organic hydroxy compound metabolic process; GO:0044107 cellular alcohol metabolic process; GO:1902652 secondary alcohol metabolic process; GO:0006066 alcohol metabolic process; GO:1902653 secondary alcohol biosynthetic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0016125 sterol metabolic process; GO:0071704 organic substance metabolic process; GO:0008610 lipid biosynthetic process; GO:0016126 sterol biosynthetic process; GO:0008152 metabolic process; GO:0008204 ergosterol metabolic process; GO:0006696 ergosterol biosynthetic process; GO:0009987 cellular process; GO:0097384 cellular lipid biosynthetic process; GO:0006629 lipid metabolic process; GO:0044711 single-organism biosynthetic process; GO:0044108 cellular alcohol biosynthetic process; GO:0044281 small molecule metabolic process; GO:0008202 steroid metabolic process; GO:0044763 single-organism cellular process; GO:0046165 alcohol biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:1901617 organic hydroxy compound biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0006694 steroid biosynthetic process; GO:0016128 phytosteroid metabolic process; GO:0044710 single-organism metabolic process; GO:0044283 small molecule biosynthetic process; GO:1901362 organic cyclic compound biosynthetic process; ","GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044432 endoplasmic reticulum part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0030133 transport vesicle; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0060090 binding, bridging; GO:0030674 protein binding, bridging; GO:0005488 binding; "]
["Q9UKS6","Protein kinase C and casein kinase substrate in neurons protein 3 OS=Homo sapiens OX=9606 GN=PACSIN3","PACSIN3",48.486,9.9859,13.4,5,5,5,0.893,0.975,0.95,1.045,0.978,1.158,1.129,0.0983,"nucleus\r","GO:0050794 regulation of cellular process; GO:0060627 regulation of vesicle-mediated transport; GO:0016043 cellular component organization; GO:0010256 endomembrane system organization; GO:0032270 positive regulation of cellular protein metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0031331 positive regulation of cellular catabolic process; GO:0051129 negative regulation of cellular component organization; GO:0044699 single-organism process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0051234 establishment of localization; GO:0045806 negative regulation of endocytosis; GO:0045862 positive regulation of proteolysis; GO:0051044 positive regulation of membrane protein ectodomain proteolysis; GO:0009893 positive regulation of metabolic process; GO:0051043 regulation of membrane protein ectodomain proteolysis; GO:0032879 regulation of localization; GO:0009896 positive regulation of catabolic process; GO:0010959 regulation of metal ion transport; GO:0042176 regulation of protein catabolic process; GO:0009987 cellular process; GO:0051051 negative regulation of transport; GO:0030100 regulation of endocytosis; GO:0043271 negative regulation of ion transport; GO:0080090 regulation of primary metabolic process; GO:0051049 regulation of transport; GO:0051926 negative regulation of calcium ion transport; GO:0031329 regulation of cellular catabolic process; GO:0016192 vesicle-mediated transport; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0043269 regulation of ion transport; GO:0044802 single-organism membrane organization; GO:0051924 regulation of calcium ion transport; GO:0048522 positive regulation of cellular process; GO:0007009 plasma membrane organization; GO:0030162 regulation of proteolysis; GO:0031323 regulation of cellular metabolic process; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0006810 transport; GO:0051247 positive regulation of protein metabolic process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0051246 regulation of protein metabolic process; GO:0061024 membrane organization; GO:0031325 positive regulation of cellular metabolic process; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0045732 positive regulation of protein catabolic process; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0097320 plasma membrane tubulation; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0019855 calcium channel inhibitor activity; GO:0008092 cytoskeletal protein binding; GO:0008200 ion channel inhibitor activity; GO:0016247 channel regulator activity; GO:0005488 binding; GO:0008289 lipid binding; GO:0099106 ion channel regulator activity; GO:0005515 protein binding; GO:0005246 calcium channel regulator activity; GO:0098772 molecular function regulator; GO:0016248 channel inhibitor activity; ","K20123",null,null,"IPR001452; IPR031160; IPR001060; ","SH3 domain; F-BAR domain; FCH domain; \r"]
["Q9UKU7","Isobutyryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAD8","ACAD8",45.069,23.185,15.7,6,6,6,1.03,0.912,0.965,1.029,1.04,0.987,1.051,0.257,"mitochondria\r","GO:1901606 alpha-amino acid catabolic process; GO:0097659 nucleic acid-templated transcription; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0043170 macromolecule metabolic process; GO:0006629 lipid metabolic process; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0055114 oxidation-reduction process; GO:0044281 small molecule metabolic process; GO:0006574 valine catabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0016070 RNA metabolic process; GO:0046395 carboxylic acid catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:1901575 organic substance catabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0009063 cellular amino acid catabolic process; GO:0006082 organic acid metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0043436 oxoacid metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0006573 valine metabolic process; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0044248 cellular catabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009081 branched-chain amino acid metabolic process; GO:0009987 cellular process; GO:0006355 regulation of transcription, DNA-templated; GO:0044712 single-organism catabolic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0044282 small molecule catabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:1901605 alpha-amino acid metabolic process; GO:0044238 primary metabolic process; GO:0051252 regulation of RNA metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0009083 branched-chain amino acid catabolic process; GO:1901565 organonitrogen compound catabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0019752 carboxylic acid metabolic process; GO:0016054 organic acid catabolic process; GO:0010467 gene expression; GO:0009056 catabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:1901265 nucleoside phosphate binding; GO:0050660 flavin adenine dinucleotide binding; GO:0043167 ion binding; GO:0000166 nucleotide binding; GO:0048037 cofactor binding; GO:0016491 oxidoreductase activity; GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043168 anion binding; GO:0003995 acyl-CoA dehydrogenase activity; GO:0050662 coenzyme binding; GO:0036094 small molecule binding; ","K11538","ACAD8; isobutyryl-CoA dehydrogenase [EC:1.3.99.-]","hsa00280 Valine, leucine and isoleucine degradation - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR009100; IPR013786; IPR006091; IPR009075; ","\"Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain; Acyl-CoA dehydrogenase/oxidase, N-terminal; Acyl-CoA oxidase/dehydrogenase, central domain; Acyl-CoA dehydrogenase/oxidase C-terminal; \"\r"]
["Q9UKV3","Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1","ACIN1",151.86,36.62,7.7,11,12,11,0.95,0.966,0.906,1.084,1.025,1.067,1.125,0.00964,"nucleus\r","GO:0065008 regulation of biological quality; GO:0010941 regulation of cell death; GO:0002262 myeloid cell homeostasis; GO:0045637 regulation of myeloid cell differentiation; GO:0048869 cellular developmental process; GO:0050686 negative regulation of mRNA processing; GO:0044699 single-organism process; GO:0051253 negative regulation of RNA metabolic process; GO:1903312 negative regulation of mRNA metabolic process; GO:0044237 cellular metabolic process; GO:0034101 erythrocyte homeostasis; GO:1902107 positive regulation of leukocyte differentiation; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0030262 apoptotic nuclear changes; GO:0006915 apoptotic process; GO:0043170 macromolecule metabolic process; GO:0048024 regulation of mRNA splicing, via spliceosome; GO:0071103 DNA conformation change; GO:0032502 developmental process; GO:0006396 RNA processing; GO:0010468 regulation of gene expression; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0050684 regulation of mRNA processing; GO:0002520 immune system development; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0032501 multicellular organismal process; GO:0010942 positive regulation of cell death; GO:0048872 homeostasis of number of cells; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:0048513 animal organ development; GO:0045655 regulation of monocyte differentiation; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0045639 positive regulation of myeloid cell differentiation; GO:1902105 regulation of leukocyte differentiation; GO:0030218 erythrocyte differentiation; GO:0044260 cellular macromolecule metabolic process; GO:0033119 negative regulation of RNA splicing; GO:0019222 regulation of metabolic process; GO:0002682 regulation of immune system process; GO:0097194 execution phase of apoptosis; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0051094 positive regulation of developmental process; GO:0048856 anatomical structure development; GO:0016071 mRNA metabolic process; GO:0043068 positive regulation of programmed cell death; GO:2000026 regulation of multicellular organismal development; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0043067 regulation of programmed cell death; GO:0043065 positive regulation of apoptotic process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0048523 negative regulation of cellular process; GO:0051239 regulation of multicellular organismal process; GO:0045597 positive regulation of cell differentiation; GO:1903706 regulation of hemopoiesis; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0030261 chromosome condensation; GO:0030154 cell differentiation; GO:0006323 DNA packaging; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:1903708 positive regulation of hemopoiesis; GO:0030099 myeloid cell differentiation; GO:0010629 negative regulation of gene expression; GO:0048731 system development; GO:0006807 nitrogen compound metabolic process; GO:0002763 positive regulation of myeloid leukocyte differentiation; GO:0002376 immune system process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0006921 cellular component disassembly involved in execution phase of apoptosis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0030097 hemopoiesis; GO:0048534 hematopoietic or lymphoid organ development; GO:0043484 regulation of RNA splicing; GO:1903311 regulation of mRNA metabolic process; GO:0051276 chromosome organization; GO:0008219 cell death; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0002761 regulation of myeloid leukocyte differentiation; GO:0002684 positive regulation of immune system process; GO:0022411 cellular component disassembly; GO:0030263 apoptotic chromosome condensation; GO:0010467 gene expression; GO:0012501 programmed cell death; GO:0045657 positive regulation of monocyte differentiation; GO:0048025 negative regulation of mRNA splicing, via spliceosome; GO:0050793 regulation of developmental process; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0061574 ASAP complex; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0003723 RNA binding; GO:1901265 nucleoside phosphate binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0016887 ATPase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0019899 enzyme binding; GO:0036094 small molecule binding; ","K12875","ACIN1; apoptotic chromatin condensation inducer in the nucleus","hsa03040 Spliceosome - Homo sapiens (human); hsa03015 mRNA surveillance pathway - Homo sapiens (human); hsa03013 RNA transport - Homo sapiens (human); ","IPR003034; IPR034257; IPR000504; IPR012677; ","\"SAP domain; Acinus, RNA recognition motif; RNA recognition motif domain; Nucleotide-binding alpha-beta plait domain; \"\r"]
["Q9UKV8","Protein argonaute-2 OS=Homo sapiens OX=9606 GN=AGO2","AGO2",97.207,14.918,8.3,7,7,3,1.14,1.017,0.89,0.966,0.985,1.016,0.974,0.781,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0022613 ribonucleoprotein complex biogenesis; GO:0006518 peptide metabolic process; GO:0022618 ribonucleoprotein complex assembly; GO:0007166 cell surface receptor signaling pathway; GO:0097659 nucleic acid-templated transcription; GO:0010608 posttranscriptional regulation of gene expression; GO:0009891 positive regulation of biosynthetic process; GO:1905616 regulation of miRNA mediated inhibition of translation; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0065003 macromolecular complex assembly; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0016055 Wnt signaling pathway; GO:0006396 RNA processing; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0009894 regulation of catabolic process; GO:0060148 positive regulation of posttranscriptional gene silencing; GO:0044763 single-organism cellular process; GO:0034249 negative regulation of cellular amide metabolic process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0007267 cell-cell signaling; GO:0031047 gene silencing by RNA; GO:0032269 negative regulation of cellular protein metabolic process; GO:1901698 response to nitrogen compound; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0090305 nucleic acid phosphodiester bond hydrolysis; GO:0006379 mRNA cleavage; GO:0016071 mRNA metabolic process; GO:0035278 miRNA mediated inhibition of translation; GO:1901362 organic cyclic compound biosynthetic process; GO:0098795 mRNA cleavage involved in gene silencing; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0045974 regulation of translation, ncRNA-mediated; GO:0044267 cellular protein metabolic process; GO:0045947 negative regulation of translational initiation; GO:0009791 post-embryonic development; GO:0017148 negative regulation of translation; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0060964 regulation of gene silencing by miRNA; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0009896 positive regulation of catabolic process; GO:0060968 regulation of gene silencing; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0007275 multicellular organism development; GO:0061013 regulation of mRNA catabolic process; GO:0010501 RNA secondary structure unwinding; GO:0048015 phosphatidylinositol-mediated signaling; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:1905618 positive regulation of miRNA mediated inhibition of translation; GO:0071359 cellular response to dsRNA; GO:0051254 positive regulation of RNA metabolic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0071407 cellular response to organic cyclic compound; GO:0060966 regulation of gene silencing by RNA; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0034248 regulation of cellular amide metabolic process; GO:0016246 RNA interference; GO:1903311 regulation of mRNA metabolic process; GO:0009890 negative regulation of biosynthetic process; GO:0031325 positive regulation of cellular metabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0035195 gene silencing by miRNA; GO:1901564 organonitrogen compound metabolic process; GO:0040033 negative regulation of translation, ncRNA-mediated; GO:0031331 positive regulation of cellular catabolic process; GO:0035194 posttranscriptional gene silencing by RNA; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0035567 non-canonical Wnt signaling pathway; GO:0048017 inositol lipid-mediated signaling; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0071826 ribonucleoprotein complex subunit organization; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0006413 translational initiation; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0006412 translation; GO:0070887 cellular response to chemical stimulus; GO:0031054 pre-miRNA processing; GO:0034470 ncRNA processing; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0060147 regulation of posttranscriptional gene silencing; GO:0031326 regulation of cellular biosynthetic process; GO:0043043 peptide biosynthetic process; GO:0035087 siRNA loading onto RISC involved in RNA interference; GO:0043331 response to dsRNA; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0007223 Wnt signaling pathway, calcium modulating pathway; GO:0070922 small RNA loading onto RISC; GO:0043603 cellular amide metabolic process; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:1903313 positive regulation of mRNA metabolic process; GO:0198738 cell-cell signaling by wnt; GO:0016070 RNA metabolic process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:1901699 cellular response to nitrogen compound; GO:0019222 regulation of metabolic process; GO:0035279 mRNA cleavage involved in gene silencing by miRNA; GO:0070918 production of small RNA involved in gene silencing by RNA; GO:0048856 anatomical structure development; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:1900153 positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:0010586 miRNA metabolic process; GO:0071704 organic substance metabolic process; GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening; GO:0061014 positive regulation of mRNA catabolic process; GO:1900151 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0090625 mRNA cleavage involved in gene silencing by siRNA; GO:0034622 cellular macromolecular complex assembly; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0035556 intracellular signal transduction; GO:0016441 posttranscriptional gene silencing; GO:0006807 nitrogen compound metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0040029 regulation of gene expression, epigenetic; GO:0035196 production of miRNAs involved in gene silencing by miRNA; GO:0090501 RNA phosphodiester bond hydrolysis; GO:0016458 gene silencing; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0006417 regulation of translation; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0031050 dsRNA fragmentation; GO:0051248 negative regulation of protein metabolic process; GO:0006446 regulation of translational initiation; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0010467 gene expression; GO:0031327 negative regulation of cellular biosynthetic process; GO:0043604 amide biosynthetic process; GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening; GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic; GO:2000637 positive regulation of gene silencing by miRNA; GO:0034660 ncRNA metabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0030425 dendrite; GO:1905348 endonuclease complex; GO:0030054 cell junction; GO:0000932 P-body; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0034518 RNA cap binding complex; GO:0005623 cell; GO:0044422 organelle part; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070578 RISC-loading complex; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043005 neuron projection; GO:0005845 mRNA cap binding complex; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0036477 somatodendritic compartment; GO:0035770 ribonucleoprotein granule; GO:0031332 RNAi effector complex; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0035068 micro-ribonucleoprotein complex; GO:0016442 RISC complex; GO:0044444 cytoplasmic part; GO:0005844 polysome; GO:0044428 nuclear part; GO:1902555 endoribonuclease complex; ","GO:0098808 mRNA cap binding; GO:0000339 RNA cap binding; GO:0000340 RNA 7-methylguanosine cap binding; GO:0004521 endoribonuclease activity; GO:0003743 translation initiation factor activity; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0070063 RNA polymerase binding; GO:0001047 core promoter binding; GO:0035197 siRNA binding; GO:0000975 regulatory region DNA binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0003729 mRNA binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043169 cation binding; GO:0008022 protein C-terminus binding; GO:0035198 miRNA binding; GO:0004519 endonuclease activity; GO:0004540 ribonuclease activity; GO:0003723 RNA binding; GO:0003677 DNA binding; GO:0001099 basal RNA polymerase II transcription machinery binding; GO:0003725 double-stranded RNA binding; GO:0043167 ion binding; GO:0000993 RNA polymerase II core binding; GO:0044877 macromolecular complex binding; GO:0070551 endoribonuclease activity, cleaving siRNA-paired mRNA; GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters; GO:0003727 single-stranded RNA binding; GO:0008135 translation factor activity, RNA binding; GO:0043175 RNA polymerase core enzyme binding; GO:0001067 regulatory region nucleic acid binding; GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters; GO:0001098 basal transcription machinery binding; GO:0044212 transcription regulatory region DNA binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0004518 nuclease activity; GO:0003676 nucleic acid binding; GO:0046872 metal ion binding; GO:0090624 endoribonuclease activity, cleaving miRNA-paired mRNA; GO:0019899 enzyme binding; GO:0032403 protein complex binding; ","K11593",null,null,"IPR032474; IPR014811; IPR032472; IPR003165; IPR032473; IPR003100; IPR012337; ","\"Protein argonaute, N-terminal; Argonaute, linker 1 domain; Argonaute linker 2 domain; Piwi domain; Protein argonaute, Mid domain; PAZ domain; Ribonuclease H-like domain; \"\r"]
["Q9UKX7","Nuclear pore complex protein Nup50 OS=Homo sapiens OX=9606 GN=NUP50","NUP50",50.144,8.9592,6.6,3,3,3,0.922,0.841,0.968,1.038,1.16,1.063,1.194,0.0289,"cytoplasm\r","GO:0050658 RNA transport; GO:0051169 nuclear transport; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:1902583 multi-organism intracellular transport; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0032879 regulation of localization; GO:0015931 nucleobase-containing compound transport; GO:0033365 protein localization to organelle; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0006606 protein import into nucleus; GO:0075733 intracellular transport of virus; GO:0044419 interspecies interaction between organisms; GO:0008104 protein localization; GO:0044765 single-organism transport; GO:0051031 tRNA transport; GO:0007077 mitotic nuclear envelope disassembly; GO:0000278 mitotic cell cycle; GO:0018130 heterocycle biosynthetic process; GO:0044763 single-organism cellular process; GO:0032774 RNA biosynthetic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0006611 protein export from nucleus; GO:0051704 multi-organism process; GO:0006810 transport; GO:0080135 regulation of cellular response to stress; GO:0031047 gene silencing by RNA; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0006913 nucleocytoplasmic transport; GO:1901362 organic cyclic compound biosynthetic process; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0016925 protein sumoylation; GO:1902593 single-organism nuclear import; GO:0051028 mRNA transport; GO:0044267 cellular protein metabolic process; GO:0080134 regulation of response to stress; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0051236 establishment of RNA localization; GO:0046483 heterocycle metabolic process; GO:1902578 single-organism localization; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0051081 nuclear envelope disassembly; GO:0044744 protein targeting to nucleus; GO:1902580 single-organism cellular localization; GO:0034613 cellular protein localization; GO:0046794 transport of virus; GO:0006403 RNA localization; GO:0006405 RNA export from nucleus; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0044766 multi-organism transport; GO:0045184 establishment of protein localization; GO:0006409 tRNA export from nucleus; GO:0032446 protein modification by small protein conjugation; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0043412 macromolecule modification; GO:0051179 localization; GO:0010256 endomembrane system organization; GO:0072594 establishment of protein localization to organelle; GO:0017038 protein import; GO:0044699 single-organism process; GO:0051168 nuclear export; GO:1902581 multi-organism cellular localization; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0051234 establishment of localization; GO:0071431 tRNA-containing ribonucleoprotein complex export from nucleus; GO:0006605 protein targeting; GO:0071427 mRNA-containing ribonucleoprotein complex export from nucleus; GO:0051649 establishment of localization in cell; GO:0050657 nucleic acid transport; GO:0033036 macromolecule localization; GO:0010827 regulation of glucose transport; GO:0010468 regulation of gene expression; GO:1901360 organic cyclic compound metabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0010605 negative regulation of macromolecule metabolic process; GO:0071166 ribonucleoprotein complex localization; GO:1902582 single-organism intracellular transport; GO:0016070 RNA metabolic process; GO:0030397 membrane disassembly; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0019222 regulation of metabolic process; GO:1900034 regulation of cellular response to heat; GO:0019083 viral transcription; GO:0036211 protein modification process; GO:0016043 cellular component organization; GO:0006997 nucleus organization; GO:1902579 multi-organism localization; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0071704 organic substance metabolic process; GO:0006998 nuclear envelope organization; GO:0018205 peptidyl-lysine modification; GO:0016032 viral process; GO:0006886 intracellular protein transport; GO:0019080 viral gene expression; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006406 mRNA export from nucleus; GO:0010629 negative regulation of gene expression; GO:0051049 regulation of transport; GO:0044802 single-organism membrane organization; GO:0006807 nitrogen compound metabolic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0018193 peptidyl-amino acid modification; GO:0070727 cellular macromolecule localization; GO:0016458 gene silencing; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0071426 ribonucleoprotein complex export from nucleus; GO:0051170 nuclear import; GO:0022411 cellular component disassembly; GO:0010467 gene expression; GO:0022402 cell cycle process; GO:0034504 protein localization to nucleus; GO:0071705 nitrogen compound transport; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005643 nuclear pore; GO:0031090 organelle membrane; GO:0005635 nuclear envelope; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005654 nucleoplasm; GO:0031965 nuclear membrane; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0031975 envelope; GO:0043227 membrane-bounded organelle; GO:0043234 protein complex; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0031267 small GTPase binding; GO:0017016 Ras GTPase binding; GO:0005488 binding; GO:0005515 protein binding; GO:0008536 Ran GTPase binding; GO:0051020 GTPase binding; GO:0019899 enzyme binding; ","K14295","NUP50; nuclear pore complex protein Nup50","hsa03013 RNA transport - Homo sapiens (human); ","IPR000156; IPR011993; IPR015007; ","\"Ran binding domain; PH domain-like; Nuclear pore complex, NUP2/50/61; \"\r"]
["Q9UL15","BAG family molecular chaperone regulator 5 OS=Homo sapiens OX=9606 GN=BAG5","BAG5",51.199,8.9228,8.7,4,4,4,0.925,0.841,1.085,1.042,0.98,1.122,1.103,0.292,"cytoplasm\r","GO:0010941 regulation of cell death; GO:0070997 neuron death; GO:1903362 regulation of cellular protein catabolic process; GO:0007399 nervous system development; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0048699 generation of neurons; GO:0009894 regulation of catabolic process; GO:0061083 regulation of protein refolding; GO:0044763 single-organism cellular process; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:2001234 negative regulation of apoptotic signaling pathway; GO:0050768 negative regulation of neurogenesis; GO:1902532 negative regulation of intracellular signal transduction; GO:0080135 regulation of cellular response to stress; GO:0007030 Golgi organization; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0061136 regulation of proteasomal protein catabolic process; GO:0048583 regulation of response to stimulus; GO:1903202 negative regulation of oxidative stress-induced cell death; GO:0045665 negative regulation of neuron differentiation; GO:0090083 regulation of inclusion body assembly; GO:0010721 negative regulation of cell development; GO:0060548 negative regulation of cell death; GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0010975 regulation of neuron projection development; GO:1903332 regulation of protein folding; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:1903051 negative regulation of proteolysis involved in cellular protein catabolic process; GO:0031399 regulation of protein modification process; GO:0043067 regulation of programmed cell death; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:1903333 negative regulation of protein folding; GO:1901799 negative regulation of proteasomal protein catabolic process; GO:0051239 regulation of multicellular organismal process; GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0051338 regulation of transferase activity; GO:0031345 negative regulation of cell projection organization; GO:0042176 regulation of protein catabolic process; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:0045861 negative regulation of proteolysis; GO:1902531 regulation of intracellular signal transduction; GO:0048731 system development; GO:0051960 regulation of nervous system development; GO:0060284 regulation of cell development; GO:0010977 negative regulation of neuron projection development; GO:0030162 regulation of proteolysis; GO:0009892 negative regulation of metabolic process; GO:1900408 negative regulation of cellular response to oxidative stress; GO:1903321 negative regulation of protein modification by small protein conjugation or removal; GO:0031330 negative regulation of cellular catabolic process; GO:0051438 regulation of ubiquitin-protein transferase activity; GO:0006996 organelle organization; GO:1902882 regulation of response to oxidative stress; GO:0050793 regulation of developmental process; GO:0051444 negative regulation of ubiquitin-protein transferase activity; GO:0051093 negative regulation of developmental process; GO:0010256 endomembrane system organization; GO:0009968 negative regulation of signal transduction; GO:0051129 negative regulation of cellular component organization; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0051241 negative regulation of multicellular organismal process; GO:0022008 neurogenesis; GO:0031400 negative regulation of protein modification process; GO:0031396 regulation of protein ubiquitination; GO:0006457 protein folding; GO:2001233 regulation of apoptotic signaling pathway; GO:0010646 regulation of cell communication; GO:2001243 negative regulation of intrinsic apoptotic signaling pathway; GO:0045596 negative regulation of cell differentiation; GO:0032502 developmental process; GO:0061084 negative regulation of protein refolding; GO:0051348 negative regulation of transferase activity; GO:1903363 negative regulation of cellular protein catabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:1902883 negative regulation of response to oxidative stress; GO:0045664 regulation of neuron differentiation; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:1900034 regulation of cellular response to heat; GO:0044092 negative regulation of molecular function; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0016043 cellular component organization; GO:0043069 negative regulation of programmed cell death; GO:0042177 negative regulation of protein catabolic process; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:0060255 regulation of macromolecule metabolic process; GO:0031344 regulation of cell projection organization; GO:1903201 regulation of oxidative stress-induced cell death; GO:0044087 regulation of cellular component biogenesis; GO:0031324 negative regulation of cellular metabolic process; GO:0030154 cell differentiation; GO:0051961 negative regulation of nervous system development; GO:0043066 negative regulation of apoptotic process; GO:0009895 negative regulation of catabolic process; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0031397 negative regulation of protein ubiquitination; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway; GO:0048585 negative regulation of response to stimulus; GO:1902176 negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway; GO:1900407 regulation of cellular response to oxidative stress; GO:0008219 cell death; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:2001242 regulation of intrinsic apoptotic signaling pathway; GO:0051248 negative regulation of protein metabolic process; GO:0051128 regulation of cellular component organization; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; GO:0050767 regulation of neurogenesis; GO:0071840 cellular component organization or biogenesis; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0016234 inclusion body; GO:0048471 perinuclear region of cytoplasm; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005829 cytosol; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0031625 ubiquitin protein ligase binding; GO:0051087 chaperone binding; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0019901 protein kinase binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0098772 molecular function regulator; GO:0019900 kinase binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0030554 adenyl nucleotide binding; GO:0060590 ATPase regulator activity; GO:0044389 ubiquitin-like protein ligase binding; GO:0000774 adenyl-nucleotide exchange factor activity; GO:0019899 enzyme binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; ","K09559",null,null,"IPR003103; ","BAG domain; \r"]
["Q9UL18","Protein argonaute-1 OS=Homo sapiens OX=9606 GN=AGO1","AGO1",97.213,7.2871,7.4,6,6,2,1.015,0.958,0.958,1.072,0.935,1.07,1.05,0.394,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0022613 ribonucleoprotein complex biogenesis; GO:0022618 ribonucleoprotein complex assembly; GO:0007166 cell surface receptor signaling pathway; GO:0097659 nucleic acid-templated transcription; GO:0010608 posttranscriptional regulation of gene expression; GO:0009891 positive regulation of biosynthetic process; GO:0044237 cellular metabolic process; GO:1901224 positive regulation of NIK/NF-kappaB signaling; GO:0008152 metabolic process; GO:0065003 macromolecular complex assembly; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0043170 macromolecule metabolic process; GO:0016055 Wnt signaling pathway; GO:0006396 RNA processing; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044763 single-organism cellular process; GO:0034249 negative regulation of cellular amide metabolic process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0007267 cell-cell signaling; GO:0031047 gene silencing by RNA; GO:0032269 negative regulation of cellular protein metabolic process; GO:0006402 mRNA catabolic process; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0016071 mRNA metabolic process; GO:0035278 miRNA mediated inhibition of translation; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0045974 regulation of translation, ncRNA-mediated; GO:0017148 negative regulation of translation; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0044248 cellular catabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0034655 nucleobase-containing compound catabolic process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0010501 RNA secondary structure unwinding; GO:0048015 phosphatidylinositol-mediated signaling; GO:0009966 regulation of signal transduction; GO:0071359 cellular response to dsRNA; GO:0051254 positive regulation of RNA metabolic process; GO:1902531 regulation of intracellular signal transduction; GO:1901222 regulation of NIK/NF-kappaB signaling; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0071407 cellular response to organic cyclic compound; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA; GO:0034248 regulation of cellular amide metabolic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0009890 negative regulation of biosynthetic process; GO:0031325 positive regulation of cellular metabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0048584 positive regulation of response to stimulus; GO:0035195 gene silencing by miRNA; GO:0040033 negative regulation of translation, ncRNA-mediated; GO:0023051 regulation of signaling; GO:0035194 posttranscriptional gene silencing by RNA; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0035567 non-canonical Wnt signaling pathway; GO:0048017 inositol lipid-mediated signaling; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0071826 ribonucleoprotein complex subunit organization; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:1901361 organic cyclic compound catabolic process; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0070887 cellular response to chemical stimulus; GO:0031054 pre-miRNA processing; GO:0034470 ncRNA processing; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0043331 response to dsRNA; GO:0070922 small RNA loading onto RISC; GO:0007223 Wnt signaling pathway, calcium modulating pathway; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0198738 cell-cell signaling by wnt; GO:0016070 RNA metabolic process; GO:0006401 RNA catabolic process; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0042221 response to chemical; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:1901699 cellular response to nitrogen compound; GO:0019222 regulation of metabolic process; GO:0070918 production of small RNA involved in gene silencing by RNA; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0071310 cellular response to organic substance; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0010586 miRNA metabolic process; GO:0071704 organic substance metabolic process; GO:0023056 positive regulation of signaling; GO:0034641 cellular nitrogen compound metabolic process; GO:0010647 positive regulation of cell communication; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0034622 cellular macromolecular complex assembly; GO:0044265 cellular macromolecule catabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0035556 intracellular signal transduction; GO:0016441 posttranscriptional gene silencing; GO:0006807 nitrogen compound metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0040029 regulation of gene expression, epigenetic; GO:0016458 gene silencing; GO:0035196 production of miRNAs involved in gene silencing by miRNA; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006417 regulation of translation; GO:0051246 regulation of protein metabolic process; GO:0009057 macromolecule catabolic process; GO:0031050 dsRNA fragmentation; GO:0051248 negative regulation of protein metabolic process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0010467 gene expression; GO:0009967 positive regulation of signal transduction; GO:0031327 negative regulation of cellular biosynthetic process; GO:0009056 catabolic process; GO:0034660 ncRNA metabolic process; GO:0071840 cellular component organization or biogenesis; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; ","GO:1905348 endonuclease complex; GO:0000932 P-body; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070578 RISC-loading complex; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0035770 ribonucleoprotein granule; GO:0031332 RNAi effector complex; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0035068 micro-ribonucleoprotein complex; GO:0016442 RISC complex; GO:0044444 cytoplasmic part; GO:0005844 polysome; GO:1902555 endoribonuclease complex; GO:0044428 nuclear part; ","GO:0003690 double-stranded DNA binding; GO:0005515 protein binding; GO:0070063 RNA polymerase binding; GO:0000987 core promoter proximal region sequence-specific DNA binding; GO:0001047 core promoter binding; GO:1901363 heterocyclic compound binding; GO:0000975 regulatory region DNA binding; GO:0097159 organic cyclic compound binding; GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding; GO:0005488 binding; GO:0035198 miRNA binding; GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding; GO:0003677 DNA binding; GO:0003723 RNA binding; GO:0001099 basal RNA polymerase II transcription machinery binding; GO:0000976 transcription regulatory region sequence-specific DNA binding; GO:0003725 double-stranded RNA binding; GO:0001012 RNA polymerase II regulatory region DNA binding; GO:1990837 sequence-specific double-stranded DNA binding; GO:0044877 macromolecular complex binding; GO:0000993 RNA polymerase II core binding; GO:0043565 sequence-specific DNA binding; GO:0003727 single-stranded RNA binding; GO:0001159 core promoter proximal region DNA binding; GO:0043175 RNA polymerase core enzyme binding; GO:0001067 regulatory region nucleic acid binding; GO:0001098 basal transcription machinery binding; GO:0044212 transcription regulatory region DNA binding; GO:0003676 nucleic acid binding; GO:0019899 enzyme binding; GO:0032403 protein complex binding; ","K11593",null,null,"IPR032472; IPR032474; IPR014811; IPR003165; IPR012337; IPR032473; IPR003100; ","\"Argonaute linker 2 domain; Protein argonaute, N-terminal; Argonaute, linker 1 domain; Piwi domain; Ribonuclease H-like domain; Protein argonaute, Mid domain; PAZ domain; \"\r"]
["Q9UL25","Ras-related protein Rab-21 OS=Homo sapiens OX=9606 GN=RAB21","RAB21",24.347,61.37,28.9,6,9,6,1.054,1.037,1.013,0.979,0.997,0.941,0.94,0.0389,"cytoplasm\r","GO:0044700 single organism signaling; GO:0060627 regulation of vesicle-mediated transport; GO:0065008 regulation of biological quality; GO:0045666 positive regulation of neuron differentiation; GO:0048869 cellular developmental process; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0051046 regulation of secretion; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0001558 regulation of cell growth; GO:0051130 positive regulation of cellular component organization; GO:0007165 signal transduction; GO:0010970 transport along microtubule; GO:1903651 positive regulation of cytoplasmic transport; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0032535 regulation of cellular component size; GO:0010720 positive regulation of cell development; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0008089 anterograde axonal transport; GO:0044765 single-organism transport; GO:0032502 developmental process; GO:0007399 nervous system development; GO:2000643 positive regulation of early endosome to late endosome transport; GO:0051716 cellular response to stimulus; GO:0048259 regulation of receptor-mediated endocytosis; GO:0048699 generation of neurons; GO:0031346 positive regulation of cell projection organization; GO:1903649 regulation of cytoplasmic transport; GO:0051962 positive regulation of nervous system development; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0032386 regulation of intracellular transport; GO:0007264 small GTPase mediated signal transduction; GO:0023052 signaling; GO:1903530 regulation of secretion by cell; GO:0032501 multicellular organismal process; GO:1902582 single-organism intracellular transport; GO:0051050 positive regulation of transport; GO:0006810 transport; GO:0008088 axo-dendritic transport; GO:0050789 regulation of biological process; GO:0045664 regulation of neuron differentiation; GO:0051094 positive regulation of developmental process; GO:0048856 anatomical structure development; GO:0048260 positive regulation of receptor-mediated endocytosis; GO:0010975 regulation of neuron projection development; GO:2000026 regulation of multicellular organismal development; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0044707 single-multicellular organism process; GO:0040008 regulation of growth; GO:0045807 positive regulation of endocytosis; GO:0017157 regulation of exocytosis; GO:0010770 positive regulation of cell morphogenesis involved in differentiation; GO:0031344 regulation of cell projection organization; GO:0048638 regulation of developmental growth; GO:0050896 response to stimulus; GO:0099111 microtubule-based transport; GO:0030705 cytoskeleton-dependent intracellular transport; GO:0051239 regulation of multicellular organismal process; GO:0048814 regulation of dendrite morphogenesis; GO:0045597 positive regulation of cell differentiation; GO:0060341 regulation of cellular localization; GO:1900006 positive regulation of dendrite development; GO:0030154 cell differentiation; GO:0008361 regulation of cell size; GO:1902578 single-organism localization; GO:2000641 regulation of early endosome to late endosome transport; GO:1902580 single-organism cellular localization; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0030100 regulation of endocytosis; GO:0035556 intracellular signal transduction; GO:0048731 system development; GO:0051049 regulation of transport; GO:0032388 positive regulation of intracellular transport; GO:0051960 regulation of nervous system development; GO:0060284 regulation of cell development; GO:0098930 axonal transport; GO:0071702 organic substance transport; GO:0007017 microtubule-based process; GO:0048518 positive regulation of biological process; GO:0050770 regulation of axonogenesis; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0050775 positive regulation of dendrite morphogenesis; GO:0007018 microtubule-based movement; GO:0030516 regulation of axon extension; GO:0010976 positive regulation of neuron projection development; GO:0044767 single-organism developmental process; GO:0061024 membrane organization; GO:0022603 regulation of anatomical structure morphogenesis; GO:0061387 regulation of extent of cell growth; GO:0090066 regulation of anatomical structure size; GO:0050773 regulation of dendrite development; GO:0006928 movement of cell or subcellular component; GO:0050769 positive regulation of neurogenesis; GO:0051128 regulation of cellular component organization; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0022604 regulation of cell morphogenesis; GO:0071840 cellular component organization or biogenesis; GO:0050767 regulation of neurogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0099568 cytoplasmic region; GO:0005737 cytoplasm; GO:0032838 cell projection cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0098559 cytoplasmic side of early endosome membrane; GO:0005623 cell; GO:0009898 cytoplasmic side of plasma membrane; GO:0032155 cell division site part; GO:0044422 organelle part; GO:0005769 early endosome; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0010009 cytoplasmic side of endosome membrane; GO:0098791 Golgi subcompartment; GO:0043005 neuron projection; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0005789 endoplasmic reticulum membrane; GO:0005924 cell-substrate adherens junction; GO:0098552 side of membrane; GO:0010008 endosome membrane; GO:0042995 cell projection; GO:0032580 Golgi cisterna membrane; GO:0070161 anchoring junction; GO:0012506 vesicle membrane; GO:0044440 endosomal part; GO:0005576 extracellular region; GO:0033267 axon part; GO:0005886 plasma membrane; GO:0030424 axon; GO:0043231 intracellular membrane-bounded organelle; GO:1904115 axon cytoplasm; GO:0031985 Golgi cisterna; GO:0043230 extracellular organelle; GO:0005783 endoplasmic reticulum; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0098562 cytoplasmic side of membrane; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0005912 adherens junction; GO:0044431 Golgi apparatus part; GO:0005768 endosome; GO:0031901 early endosome membrane; GO:0032154 cleavage furrow; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0097610 cell surface furrow; GO:0044446 intracellular organelle part; GO:0032153 cell division site; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0005795 Golgi stack; GO:0044463 cell projection part; GO:0005829 cytosol; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0044432 endoplasmic reticulum part; GO:0005802 trans-Golgi network; GO:0009986 cell surface; GO:0005794 Golgi apparatus; GO:0031984 organelle subcompartment; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016462 pyrophosphatase activity; GO:0019003 GDP binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0003924 GTPase activity; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; ","K07890",null,null,"IPR005225; IPR027417; ","Small GTP-binding protein domain; P-loop containing nucleoside triphosphate hydrolase; \r"]
["Q9UL26","Ras-related protein Rab-22A OS=Homo sapiens OX=9606 GN=RAB22A","RAB22A",21.855,10.646,25.3,4,7,2,0.885,0.993,1.005,1.113,0.97,1.039,1.083,0.233,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0016043 cellular component organization; GO:0010256 endomembrane system organization; GO:0065008 regulation of biological quality; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0032535 regulation of cellular component size; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0009987 cellular process; GO:0051716 cellular response to stimulus; GO:0035556 intracellular signal transduction; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0016050 vesicle organization; GO:0071702 organic substance transport; GO:0007264 small GTPase mediated signal transduction; GO:0023052 signaling; GO:0006897 endocytosis; GO:0006810 transport; GO:0045184 establishment of protein localization; GO:0097494 regulation of vesicle size; GO:0050789 regulation of biological process; GO:0006996 organelle organization; GO:0090066 regulation of anatomical structure size; GO:0051179 localization; GO:0007032 endosome organization; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005856 cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0030670 phagocytic vesicle membrane; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0030139 endocytic vesicle; GO:0043227 membrane-bounded organelle; GO:0031252 cell leading edge; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0010008 endosome membrane; GO:0042995 cell projection; GO:0098588 bounding membrane of organelle; GO:0005770 late endosome; GO:0030666 endocytic vesicle membrane; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0045335 phagocytic vesicle; GO:0005576 extracellular region; GO:0015629 actin cytoskeleton; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0001726 ruffle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016462 pyrophosphatase activity; GO:0019003 GDP binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0003924 GTPase activity; GO:0032550 purine ribonucleoside binding; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; ","K07891","RAB22; Ras-related protein Rab-22","hsa04144 Endocytosis - Homo sapiens (human); ","IPR005225; IPR027417; ","Small GTP-binding protein domain; P-loop containing nucleoside triphosphate hydrolase; \r"]
["Q9UL46","Proteasome activator complex subunit 2 OS=Homo sapiens OX=9606 GN=PSME2","PSME2",27.401,57.841,28.9,8,20,8,0.884,0.809,0.803,1.178,1.183,1.131,1.399,0.000583,"cytoplasm\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0002220 innate immune response activating cell surface receptor signaling pathway; GO:0007166 cell surface receptor signaling pathway; GO:0010608 posttranscriptional regulation of gene expression; GO:0051443 positive regulation of ubiquitin-protein transferase activity; GO:0031347 regulation of defense response; GO:0071345 cellular response to cytokine stimulus; GO:0044237 cellular metabolic process; GO:0010564 regulation of cell cycle process; GO:1903364 positive regulation of cellular protein catabolic process; GO:0008152 metabolic process; GO:0044093 positive regulation of molecular function; GO:0090263 positive regulation of canonical Wnt signaling pathway; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0051347 positive regulation of transferase activity; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0016055 Wnt signaling pathway; GO:1903362 regulation of cellular protein catabolic process; GO:0052548 regulation of endopeptidase activity; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0010950 positive regulation of endopeptidase activity; GO:0006521 regulation of cellular amino acid metabolic process; GO:0002758 innate immune response-activating signal transduction; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0010972 negative regulation of G2/M transition of mitotic cell cycle; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0060828 regulation of canonical Wnt signaling pathway; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0033209 tumor necrosis factor-mediated signaling pathway; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0000165 MAPK cascade; GO:1903506 regulation of nucleic acid-templated transcription; GO:2000058 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:1901575 organic substance catabolic process; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0010948 negative regulation of cell cycle process; GO:0007267 cell-cell signaling; GO:0002223 stimulatory C-type lectin receptor signaling pathway; GO:0051336 regulation of hydrolase activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0044710 single-organism metabolic process; GO:0030163 protein catabolic process; GO:0050790 regulation of catalytic activity; GO:0061136 regulation of proteasomal protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0060071 Wnt signaling pathway, planar cell polarity pathway; GO:0010604 positive regulation of macromolecule metabolic process; GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:0002682 regulation of immune system process; GO:0006464 cellular protein modification process; GO:0031145 anaphase-promoting complex-dependent catabolic process; GO:0010952 positive regulation of peptidase activity; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016310 phosphorylation; GO:0033554 cellular response to stress; GO:0007346 regulation of mitotic cell cycle; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0051239 regulation of multicellular organismal process; GO:0043487 regulation of RNA stability; GO:0000209 protein polyubiquitination; GO:0031349 positive regulation of defense response; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0051345 positive regulation of hydrolase activity; GO:0009889 regulation of biosynthetic process; GO:1901987 regulation of cell cycle phase transition; GO:0009896 positive regulation of catabolic process; GO:0043620 regulation of DNA-templated transcription in response to stress; GO:0070482 response to oxygen levels; GO:0051338 regulation of transferase activity; GO:0044248 cellular catabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0010389 regulation of G2/M transition of mitotic cell cycle; GO:0042176 regulation of protein catabolic process; GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; GO:0038093 Fc receptor signaling pathway; GO:0050778 positive regulation of immune response; GO:0009966 regulation of signal transduction; GO:0023014 signal transduction by protein phosphorylation; GO:0071456 cellular response to hypoxia; GO:0038061 NIK/NF-kappaB signaling; GO:0002253 activation of immune response; GO:0006950 response to stress; GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; GO:0016567 protein ubiquitination; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress; GO:1904666 regulation of ubiquitin protein ligase activity; GO:1903321 negative regulation of protein modification by small protein conjugation or removal; GO:0055085 transmembrane transport; GO:0051247 positive regulation of protein metabolic process; GO:0051438 regulation of ubiquitin-protein transferase activity; GO:0031398 positive regulation of protein ubiquitination; GO:0032446 protein modification by small protein conjugation; GO:0006793 phosphorus metabolic process; GO:0030111 regulation of Wnt signaling pathway; GO:0031325 positive regulation of cellular metabolic process; GO:0030177 positive regulation of Wnt signaling pathway; GO:1904668 positive regulation of ubiquitin protein ligase activity; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0036293 response to decreased oxygen levels; GO:0051179 localization; GO:0043412 macromolecule modification; GO:0048584 positive regulation of response to stimulus; GO:0050793 regulation of developmental process; GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process; GO:0051444 negative regulation of ubiquitin-protein transferase activity; GO:2000045 regulation of G1/S transition of mitotic cell cycle; GO:0070646 protein modification by small protein removal; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0031331 positive regulation of cellular catabolic process; GO:0090090 negative regulation of canonical Wnt signaling pathway; GO:0044699 single-organism process; GO:0031400 negative regulation of protein modification process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0035567 non-canonical Wnt signaling pathway; GO:0031396 regulation of protein ubiquitination; GO:1905330 regulation of morphogenesis of an epithelium; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0045930 negative regulation of mitotic cell cycle; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0045088 regulation of innate immune response; GO:0009893 positive regulation of metabolic process; GO:1901991 negative regulation of mitotic cell cycle phase transition; GO:1902806 regulation of cell cycle G1/S phase transition; GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0034612 response to tumor necrosis factor; GO:0051726 regulation of cell cycle; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0070887 cellular response to chemical stimulus; GO:0050851 antigen receptor-mediated signaling pathway; GO:0010468 regulation of gene expression; GO:0030178 negative regulation of Wnt signaling pathway; GO:0034097 response to cytokine; GO:0031326 regulation of cellular biosynthetic process; GO:0048002 antigen processing and presentation of peptide antigen; GO:0048522 positive regulation of cellular process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0051348 negative regulation of transferase activity; GO:0070647 protein modification by small protein conjugation or removal; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0198738 cell-cell signaling by wnt; GO:0010565 regulation of cellular ketone metabolic process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0036211 protein modification process; GO:0052547 regulation of peptidase activity; GO:2000026 regulation of multicellular organismal development; GO:0090175 regulation of establishment of planar polarity; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0045786 negative regulation of cell cycle; GO:1904667 negative regulation of ubiquitin protein ligase activity; GO:0002218 activation of innate immune response; GO:0044257 cellular protein catabolic process; GO:0071356 cellular response to tumor necrosis factor; GO:1901988 negative regulation of cell cycle phase transition; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0016579 protein deubiquitination; GO:0050896 response to stimulus; GO:0010498 proteasomal protein catabolic process; GO:0071704 organic substance metabolic process; GO:1903322 positive regulation of protein modification by small protein conjugation or removal; GO:0045862 positive regulation of proteolysis; GO:2000027 regulation of organ morphogenesis; GO:0006468 protein phosphorylation; GO:0023056 positive regulation of signaling; GO:0001666 response to hypoxia; GO:0002757 immune response-activating signal transduction; GO:0006508 proteolysis; GO:0010647 positive regulation of cell communication; GO:0071453 cellular response to oxygen levels; GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:0019221 cytokine-mediated signaling pathway; GO:0009987 cellular process; GO:0033238 regulation of cellular amine metabolic process; GO:0031397 negative regulation of protein ubiquitination; GO:0043632 modification-dependent macromolecule catabolic process; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0045089 positive regulation of innate immune response; GO:0006355 regulation of transcription, DNA-templated; GO:0035556 intracellular signal transduction; GO:0019941 modification-dependent protein catabolic process; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0031401 positive regulation of protein modification process; GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia; GO:1902749 regulation of cell cycle G2/M phase transition; GO:0043488 regulation of mRNA stability; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0019882 antigen processing and presentation; GO:0050852 T cell receptor signaling pathway; GO:0051246 regulation of protein metabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0002684 positive regulation of immune system process; GO:0009057 macromolecule catabolic process; GO:0038095 Fc-epsilon receptor signaling pathway; GO:0051248 negative regulation of protein metabolic process; GO:0022402 cell cycle process; GO:0045732 positive regulation of protein catabolic process; GO:0009967 positive regulation of signal transduction; GO:1902750 negative regulation of cell cycle G2/M phase transition; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0036294 cellular response to decreased oxygen levels; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:1905369 endopeptidase complex; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0022624 proteasome accessory complex; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:1905368 peptidase complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0000502 proteasome complex; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0043234 protein complex; GO:0008537 proteasome activator complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0042802 identical protein binding; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0061134 peptidase regulator activity; GO:0016504 peptidase activator activity; GO:0061135 endopeptidase regulator activity; GO:0005515 protein binding; GO:0061133 endopeptidase activator activity; GO:0098772 molecular function regulator; GO:0008047 enzyme activator activity; ","K06697","PSME2; proteasome activator subunit 2 (PA28 beta)","hsa03050 Proteasome - Homo sapiens (human); hsa04612 Antigen processing and presentation - Homo sapiens (human); ","IPR003186; IPR003185; ","\"Proteasome activator pa28, C-terminal domain; Proteasome activator pa28, N-terminal domain; \"\r"]
["Q9UL62","Short transient receptor potential channel 5 OS=Homo sapiens OX=9606 GN=TRPC5","TRPC5",111.41,1.9075,0.7,1,2,1,1.129,0.926,1.069,0.931,1.026,0.929,0.924,0.319,"plasma membrane\r","GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:2000171 negative regulation of dendrite development; GO:0045927 positive regulation of growth; GO:0001558 regulation of cell growth; GO:0000041 transition metal ion transport; GO:0050774 negative regulation of dendrite morphogenesis; GO:0051240 positive regulation of multicellular organismal process; GO:0032535 regulation of cellular component size; GO:0010800 positive regulation of peptidyl-threonine phosphorylation; GO:0055065 metal ion homeostasis; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0007399 nervous system development; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0030307 positive regulation of cell growth; GO:0080090 regulation of primary metabolic process; GO:0031346 positive regulation of cell projection organization; GO:0048699 generation of neurons; GO:0045773 positive regulation of axon extension; GO:0044763 single-organism cellular process; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0006874 cellular calcium ion homeostasis; GO:0050768 negative regulation of neurogenesis; GO:0006810 transport; GO:0045665 negative regulation of neuron differentiation; GO:0010604 positive regulation of macromolecule metabolic process; GO:0010721 negative regulation of cell development; GO:0051094 positive regulation of developmental process; GO:0098662 inorganic cation transmembrane transport; GO:0010975 regulation of neuron projection development; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0034220 ion transmembrane transport; GO:0042127 regulation of cell proliferation; GO:0030001 metal ion transport; GO:0031399 regulation of protein modification process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0048814 regulation of dendrite morphogenesis; GO:0051239 regulation of multicellular organismal process; GO:0045597 positive regulation of cell differentiation; GO:0050772 positive regulation of axonogenesis; GO:0031345 negative regulation of cell projection organization; GO:0007275 multicellular organism development; GO:0048878 chemical homeostasis; GO:0070588 calcium ion transmembrane transport; GO:0010771 negative regulation of cell morphogenesis involved in differentiation; GO:0048731 system development; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0010977 negative regulation of neuron projection development; GO:0050770 regulation of axonogenesis; GO:0030182 neuron differentiation; GO:0055085 transmembrane transport; GO:0051247 positive regulation of protein metabolic process; GO:0030516 regulation of axon extension; GO:0010976 positive regulation of neuron projection development; GO:0006873 cellular ion homeostasis; GO:0006811 ion transport; GO:0031325 positive regulation of cellular metabolic process; GO:0061387 regulation of extent of cell growth; GO:0050769 positive regulation of neurogenesis; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:0007204 positive regulation of cytosolic calcium ion concentration; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0008284 positive regulation of cell proliferation; GO:0070838 divalent metal ion transport; GO:0051093 negative regulation of developmental process; GO:0045666 positive regulation of neuron differentiation; GO:0072503 cellular divalent inorganic cation homeostasis; GO:0048869 cellular developmental process; GO:0051129 negative regulation of cellular component organization; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0051241 negative regulation of multicellular organismal process; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0009893 positive regulation of metabolic process; GO:0010720 positive regulation of cell development; GO:0045596 negative regulation of cell differentiation; GO:0032502 developmental process; GO:0045937 positive regulation of phosphate metabolic process; GO:0098655 cation transmembrane transport; GO:0048639 positive regulation of developmental growth; GO:0050801 ion homeostasis; GO:0055074 calcium ion homeostasis; GO:0051962 positive regulation of nervous system development; GO:0098771 inorganic ion homeostasis; GO:0048522 positive regulation of cellular process; GO:0019725 cellular homeostasis; GO:0042391 regulation of membrane potential; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0045664 regulation of neuron differentiation; GO:1902630 regulation of membrane hyperpolarization; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0048856 anatomical structure development; GO:0072507 divalent inorganic cation homeostasis; GO:2000026 regulation of multicellular organismal development; GO:0016043 cellular component organization; GO:0072511 divalent inorganic cation transport; GO:0040008 regulation of growth; GO:0010799 regulation of peptidyl-threonine phosphorylation; GO:0060255 regulation of macromolecule metabolic process; GO:0051480 regulation of cytosolic calcium ion concentration; GO:0030003 cellular cation homeostasis; GO:0010770 positive regulation of cell morphogenesis involved in differentiation; GO:0031344 regulation of cell projection organization; GO:0048638 regulation of developmental growth; GO:0006828 manganese ion transport; GO:0055082 cellular chemical homeostasis; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:0008361 regulation of cell size; GO:0006812 cation transport; GO:0055080 cation homeostasis; GO:0051961 negative regulation of nervous system development; GO:0006816 calcium ion transport; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0098660 inorganic ion transmembrane transport; GO:0001932 regulation of protein phosphorylation; GO:0031401 positive regulation of protein modification process; GO:0001934 positive regulation of protein phosphorylation; GO:0048518 positive regulation of biological process; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0090066 regulation of anatomical structure size; GO:0050773 regulation of dendrite development; GO:0006875 cellular metal ion homeostasis; GO:0051128 regulation of cellular component organization; GO:0022604 regulation of cell morphogenesis; GO:0071840 cellular component organization or biogenesis; GO:0050767 regulation of neurogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0030425 dendrite; GO:0098857 membrane microdomain; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0043025 neuronal cell body; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0030426 growth cone; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0098805 whole membrane; GO:0098589 membrane region; GO:0043005 neuron projection; GO:0034702 ion channel complex; GO:1990351 transporter complex; GO:0045121 membrane raft; GO:0097458 neuron part; GO:0042995 cell projection; GO:0031226 intrinsic component of plasma membrane; GO:0034703 cation channel complex; GO:1902495 transmembrane transporter complex; GO:0030427 site of polarized growth; GO:0044463 cell projection part; GO:0016021 integral component of membrane; GO:0034704 calcium channel complex; GO:0005886 plasma membrane; GO:0036477 somatodendritic compartment; GO:0044459 plasma membrane part; GO:0044297 cell body; ","GO:0015075 ion transmembrane transporter activity; GO:0051117 ATPase binding; GO:0043167 ion binding; GO:0022803 passive transmembrane transporter activity; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0015279 store-operated calcium channel activity; GO:0015267 channel activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0046873 metal ion transmembrane transporter activity; GO:0030276 clathrin binding; GO:0072509 divalent inorganic cation transmembrane transporter activity; GO:0008092 cytoskeletal protein binding; GO:0022838 substrate-specific channel activity; GO:0043178 alcohol binding; GO:0005488 binding; GO:0042805 actinin binding; GO:0070679 inositol 1,4,5 trisphosphate binding; GO:0005261 cation channel activity; GO:0003779 actin binding; GO:0015085 calcium ion transmembrane transporter activity; GO:0043168 anion binding; GO:0005216 ion channel activity; GO:0022890 inorganic cation transmembrane transporter activity; GO:0005262 calcium channel activity; GO:0019899 enzyme binding; GO:0008324 cation transmembrane transporter activity; GO:0036094 small molecule binding; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; ","K04968","TRPC5; transient receptor potential cation channel subfamily C member 5","hsa04360 Axon guidance - Homo sapiens (human); ","IPR020683; IPR005821; IPR013555; ","Ankyrin repeat-containing domain; Ion transport domain; Transient receptor ion channel domain; \r"]
["Q9ULA0","Aspartyl aminopeptidase OS=Homo sapiens OX=9606 GN=DNPEP","DNPEP",52.428,54.147,22.7,11,17,11,1.034,1.083,0.967,0.935,0.925,0.947,0.91,0.0502,"nucleus\r","GO:0008152 metabolic process; GO:0006518 peptide metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0006508 proteolysis; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0043603 cellular amide metabolic process; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0009987 cellular process; GO:0071704 organic substance metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0005615 extracellular space; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0072562 blood microparticle; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0008238 exopeptidase activity; GO:0008233 peptidase activity; GO:0043167 ion binding; GO:0070006 metalloaminopeptidase activity; GO:0008235 metalloexopeptidase activity; GO:0004177 aminopeptidase activity; GO:0008237 metallopeptidase activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0008270 zinc ion binding; GO:0042802 identical protein binding; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0043169 cation binding; GO:0046872 metal ion binding; ","K01267",null,null,"IPR023358; ","\"Peptidase M18, domain 2; \"\r"]
["Q9ULC4","Malignant T-cell-amplified sequence 1 OS=Homo sapiens OX=9606 GN=MCTS1","MCTS1",20.555,18.044,12.2,3,4,3,0.949,0.923,0.957,1.031,1.094,1.046,1.121,0.00554,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0006518 peptide metabolic process; GO:0022618 ribonucleoprotein complex assembly; GO:0097659 nucleic acid-templated transcription; GO:0044699 single-organism process; GO:1903008 organelle disassembly; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0071826 ribonucleoprotein complex subunit organization; GO:0002181 cytoplasmic translation; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0006413 translational initiation; GO:0002190 cap-independent translational initiation; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006412 translation; GO:0002183 cytoplasmic translational initiation; GO:0051716 cellular response to stimulus; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0043043 peptide biosynthetic process; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0043603 cellular amide metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0016070 RNA metabolic process; GO:1902589 single-organism organelle organization; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0032988 ribonucleoprotein complex disassembly; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0016043 cellular component organization; GO:0040008 regulation of growth; GO:0042127 regulation of cell proliferation; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0002188 translation reinitiation; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:0032790 ribosome disassembly; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0034622 cellular macromolecular complex assembly; GO:0006355 regulation of transcription, DNA-templated; GO:0006950 response to stress; GO:0002192 IRES-dependent translational initiation; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0032984 macromolecular complex disassembly; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:1901576 organic substance biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0006974 cellular response to DNA damage stimulus; GO:0043933 macromolecular complex subunit organization; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0006996 organelle organization; GO:0001731 formation of translation preinitiation complex; GO:0022411 cellular component disassembly; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0007049 cell cycle; GO:0008284 positive regulation of cell proliferation; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0071944 cell periphery; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0005886 plasma membrane; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0008135 translation factor activity, RNA binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0003743 translation initiation factor activity; GO:0005515 protein binding; ","K07575",null,null,"IPR015947; IPR002478; IPR004521; ","PUA-like domain; PUA domain; Uncharacterised domain CHP00451; \r"]
["Q9ULH1","Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ASAP1","ASAP1",125.5,14.355,3.7,4,6,3,1.12,0.938,0.848,1.044,1.086,0.973,1.068,0.461,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0051093 negative regulation of developmental process; GO:2000171 negative regulation of dendrite development; GO:0048869 cellular developmental process; GO:0051129 negative regulation of cellular component organization; GO:0022008 neurogenesis; GO:0051241 negative regulation of multicellular organismal process; GO:0060271 cilium assembly; GO:0044699 single-organism process; GO:1902115 regulation of organelle assembly; GO:0044782 cilium organization; GO:0051130 positive regulation of cellular component organization; GO:1903729 regulation of plasma membrane organization; GO:0071801 regulation of podosome assembly; GO:0022607 cellular component assembly; GO:0044093 positive regulation of molecular function; GO:0031334 positive regulation of protein complex assembly; GO:0045596 negative regulation of cell differentiation; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0071803 positive regulation of podosome assembly; GO:0060998 regulation of dendritic spine development; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0032501 multicellular organismal process; GO:0050768 negative regulation of neurogenesis; GO:1902589 single-organism organelle organization; GO:0043254 regulation of protein complex assembly; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:0045664 regulation of neuron differentiation; GO:1903527 positive regulation of membrane tubulation; GO:0010638 positive regulation of organelle organization; GO:0030030 cell projection organization; GO:1902117 positive regulation of organelle assembly; GO:0050790 regulation of catalytic activity; GO:0045665 negative regulation of neuron differentiation; GO:0065009 regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0010721 negative regulation of cell development; GO:0048856 anatomical structure development; GO:0010975 regulation of neuron projection development; GO:2000026 regulation of multicellular organismal development; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0044087 regulation of cellular component biogenesis; GO:0031344 regulation of cell projection organization; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0051239 regulation of multicellular organismal process; GO:1903525 regulation of membrane tubulation; GO:0030154 cell differentiation; GO:0051345 positive regulation of hydrolase activity; GO:0070925 organelle assembly; GO:0051961 negative regulation of nervous system development; GO:0031345 negative regulation of cell projection organization; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0043547 positive regulation of GTPase activity; GO:0048731 system development; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0033043 regulation of organelle organization; GO:0010977 negative regulation of neuron projection development; GO:0048518 positive regulation of biological process; GO:0030031 cell projection assembly; GO:0043085 positive regulation of catalytic activity; GO:0044767 single-organism developmental process; GO:0006996 organelle organization; GO:0061000 negative regulation of dendritic spine development; GO:0050773 regulation of dendrite development; GO:0051128 regulation of cellular component organization; GO:0050793 regulation of developmental process; GO:0044089 positive regulation of cellular component biogenesis; GO:0050767 regulation of neurogenesis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0030425 dendrite; GO:0016020 membrane; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0043197 dendritic spine; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0098590 plasma membrane region; GO:0044309 neuron spine; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0043005 neuron projection; GO:0097458 neuron part; GO:0044456 synapse part; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0002102 podosome; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0015629 actin cytoskeleton; GO:0005886 plasma membrane; GO:0045202 synapse; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0044459 plasma membrane part; GO:0098794 postsynapse; GO:0031253 cell projection membrane; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:1901981 phosphatidylinositol phosphate binding; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0030695 GTPase regulator activity; GO:0043167 ion binding; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0001786 phosphatidylserine binding; GO:1902936 phosphatidylinositol bisphosphate binding; GO:0050839 cell adhesion molecule binding; GO:0072341 modified amino acid binding; GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0005546 phosphatidylinositol-4,5-bisphosphate binding; GO:0005543 phospholipid binding; GO:0035091 phosphatidylinositol binding; GO:0045296 cadherin binding; GO:0008289 lipid binding; GO:0046872 metal ion binding; GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0008047 enzyme activator activity; GO:0005096 GTPase activator activity; ","K12488","ASAP; Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein","hsa04666 Fc gamma R-mediated phagocytosis - Homo sapiens (human); hsa04144 Endocytosis - Homo sapiens (human); ","IPR001452; IPR027267; IPR011993; IPR020683; IPR001849; ","SH3 domain; Arfaptin homology (AH) domain/BAR domain; PH domain-like; Ankyrin repeat-containing domain; Pleckstrin homology domain; \r"]
["Q9ULP9","TBC1 domain family member 24 OS=Homo sapiens OX=9606 GN=TBC1D24","TBC1D24",62.919,3.2971,2,1,1,1,1.039,0.963,1.1,0.952,1.063,0.893,0.937,0.361,"cytoplasm\r","GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0048468 cell development; GO:0030154 cell differentiation; GO:0051345 positive regulation of hydrolase activity; GO:0044093 positive regulation of molecular function; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0043547 positive regulation of GTPase activity; GO:0048731 system development; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0031175 neuron projection development; GO:0032501 multicellular organismal process; GO:0043085 positive regulation of catalytic activity; GO:0030182 neuron differentiation; GO:0051336 regulation of hydrolase activity; GO:0030030 cell projection organization; GO:0050790 regulation of catalytic activity; GO:0044767 single-organism developmental process; GO:0065009 regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0048856 anatomical structure development; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0042995 cell projection; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0031594 neuromuscular junction; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044463 cell projection part; GO:0033267 axon part; GO:0043679 axon terminus; GO:0005886 plasma membrane; GO:0045202 synapse; GO:0030424 axon; GO:0005622 intracellular; GO:0098793 presynapse; GO:0044464 cell part; GO:0043195 terminal bouton; GO:0043005 neuron projection; GO:0044306 neuron projection terminus; GO:0097458 neuron part; GO:0044456 synapse part; ","GO:0030234 enzyme regulator activity; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0005488 binding; GO:0030695 GTPase regulator activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0008047 enzyme activator activity; GO:0005096 GTPase activator activity; ",{"$nulls":3},"IPR006571; IPR000195; ","TLDc domain; Rab-GTPase-TBC domain; \r"]
["Q9ULT8","E3 ubiquitin-protein ligase HECTD1 OS=Homo sapiens OX=9606 GN=HECTD1","HECTD1",289.38,11.817,2.4,5,5,5,1.018,1.194,1.047,0.868,0.908,0.984,0.847,0.0546,"nucleus\r","GO:0008152 metabolic process; GO:0032446 protein modification by small protein conjugation; GO:0016567 protein ubiquitination; GO:0044260 cellular macromolecule metabolic process; GO:0044267 cellular protein metabolic process; GO:0006464 cellular protein modification process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:0044238 primary metabolic process; GO:0009987 cellular process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; ",null,"GO:0019787 ubiquitin-like protein transferase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0004842 ubiquitin-protein transferase activity; GO:0043167 ion binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0016740 transferase activity; ","K12231",null,null,"IPR012919; IPR010606; IPR011989; IPR020683; IPR016024; IPR000569; IPR008979; ","SUN domain; Mib-herc2; Armadillo-like helical; Ankyrin repeat-containing domain; Armadillo-type fold; HECT domain; Galactose-binding domain-like; \r"]
["Q9ULU4","Protein kinase C-binding protein 1 OS=Homo sapiens OX=9606 GN=ZMYND8","ZMYND8",131.69,2.2141,0.6,1,1,1,0.964,0.924,0.905,0.947,1.214,1.042,1.147,0.152,"nucleus\r","GO:0065008 regulation of biological quality; GO:1905874 regulation of postsynaptic density organization; GO:0060491 regulation of cell projection assembly; GO:0097659 nucleic acid-templated transcription; GO:0044237 cellular metabolic process; GO:0050807 regulation of synapse organization; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0007399 nervous system development; GO:0018130 heterocycle biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0031346 positive regulation of cell projection organization; GO:0044763 single-organism cellular process; GO:0000122 negative regulation of transcription from RNA polymerase II promoter; GO:0032774 RNA biosynthetic process; GO:2000146 negative regulation of cell motility; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0060999 positive regulation of dendritic spine development; GO:0006464 cellular protein modification process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0051094 positive regulation of developmental process; GO:0010975 regulation of neuron projection development; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0016570 histone modification; GO:0044267 cellular protein metabolic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0051239 regulation of multicellular organismal process; GO:0045597 positive regulation of cell differentiation; GO:0060341 regulation of cellular localization; GO:0045892 negative regulation of transcription, DNA-templated; GO:1900006 positive regulation of dendrite development; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:2000145 regulation of cell motility; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0032880 regulation of protein localization; GO:0016569 covalent chromatin modification; GO:0009966 regulation of signal transduction; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:1903758 negative regulation of transcription from RNA polymerase II promoter by histone modification; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0050804 modulation of synaptic transmission; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1902897 regulation of postsynaptic density protein 95 clustering; GO:0030334 regulation of cell migration; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0051491 positive regulation of filopodium assembly; GO:0009890 negative regulation of biosynthetic process; GO:0051276 chromosome organization; GO:0010976 positive regulation of neuron projection development; GO:0030336 negative regulation of cell migration; GO:0006996 organelle organization; GO:0050769 positive regulation of neurogenesis; GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification; GO:0043412 macromolecule modification; GO:0050793 regulation of developmental process; GO:1903827 regulation of cellular protein localization; GO:0045666 positive regulation of neuron differentiation; GO:0098815 modulation of excitatory postsynaptic potential; GO:1901626 regulation of postsynaptic membrane organization; GO:0023051 regulation of signaling; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0009058 biosynthetic process; GO:0051253 negative regulation of RNA metabolic process; GO:0051130 positive regulation of cellular component organization; GO:0040013 negative regulation of locomotion; GO:2001141 regulation of RNA biosynthetic process; GO:0010646 regulation of cell communication; GO:0010720 positive regulation of cell development; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0060998 regulation of dendritic spine development; GO:0031326 regulation of cellular biosynthetic process; GO:0051962 positive regulation of nervous system development; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0042391 regulation of membrane potential; GO:0016070 RNA metabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0045664 regulation of neuron differentiation; GO:0006351 transcription, DNA-templated; GO:1902679 negative regulation of RNA biosynthetic process; GO:0019222 regulation of metabolic process; GO:0006325 chromatin organization; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0051271 negative regulation of cellular component movement; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031344 regulation of cell projection organization; GO:0044087 regulation of cellular component biogenesis; GO:0031324 negative regulation of cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0051489 regulation of filopodium assembly; GO:1905475 regulation of protein localization to membrane; GO:0030154 cell differentiation; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:1902950 regulation of dendritic spine maintenance; GO:0045595 regulation of cell differentiation; GO:0050803 regulation of synapse structure or activity; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:1902952 positive regulation of dendritic spine maintenance; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0033043 regulation of organelle organization; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044767 single-organism developmental process; GO:0050773 regulation of dendrite development; GO:0010467 gene expression; GO:0031327 negative regulation of cellular biosynthetic process; GO:0051128 regulation of cellular component organization; GO:0040012 regulation of locomotion; GO:0044089 positive regulation of cellular component biogenesis; GO:0050767 regulation of neurogenesis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0030425 dendrite; GO:0042995 cell projection; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0044463 cell projection part; GO:0005623 cell; GO:0043197 dendritic spine; GO:0045202 synapse; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0036477 somatodendritic compartment; GO:0098794 postsynapse; GO:0044309 neuron spine; GO:0005622 intracellular; GO:0044464 cell part; GO:0043005 neuron projection; GO:0043198 dendritic shaft; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0044456 synapse part; ","GO:0047485 protein N-terminus binding; GO:0035064 methylated histone binding; GO:0003690 double-stranded DNA binding; GO:0005515 protein binding; GO:0003682 chromatin binding; GO:0097159 organic cyclic compound binding; GO:0000975 regulatory region DNA binding; GO:1901363 heterocyclic compound binding; GO:0070491 repressing transcription factor binding; GO:0070577 lysine-acetylated histone binding; GO:0005488 binding; GO:0001106 RNA polymerase II transcription corepressor activity; GO:0000989 transcription factor activity, transcription factor binding; GO:0043169 cation binding; GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding; GO:0042393 histone binding; GO:0003677 DNA binding; GO:0003714 transcription corepressor activity; GO:0000976 transcription regulatory region sequence-specific DNA binding; GO:1990837 sequence-specific double-stranded DNA binding; GO:0043167 ion binding; GO:0001012 RNA polymerase II regulatory region DNA binding; GO:0043565 sequence-specific DNA binding; GO:0008270 zinc ion binding; GO:0003712 transcription cofactor activity; GO:0001067 regulatory region nucleic acid binding; GO:0001104 RNA polymerase II transcription cofactor activity; GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding; GO:0046914 transition metal ion binding; GO:0044212 transcription regulatory region DNA binding; GO:0003676 nucleic acid binding; GO:0046872 metal ion binding; GO:0000988 transcription factor activity, protein binding; GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding; GO:0008134 transcription factor binding; ",{"$nulls":3},"IPR002893; IPR013083; IPR001965; IPR011011; IPR000313; IPR001487; IPR019787; ","\"Zinc finger, MYND-type; Zinc finger, RING/FYVE/PHD-type; Zinc finger, PHD-type; Zinc finger, FYVE/PHD-type; PWWP domain; Bromodomain; Zinc finger, PHD-finger; \"\r"]
["Q9ULV4","Coronin-1C OS=Homo sapiens OX=9606 GN=CORO1C","CORO1C",53.248,83.996,31.9,17,27,15,1.031,1.055,1.016,0.957,0.991,0.981,0.944,0.0191,"mitochondria\r","GO:0044700 single organism signaling; GO:0060491 regulation of cell projection assembly; GO:0010762 regulation of fibroblast migration; GO:0001755 neural crest cell migration; GO:0030036 actin cytoskeleton organization; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0008104 protein localization; GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation; GO:0044765 single-organism transport; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0051174 regulation of phosphorus metabolic process; GO:2000394 positive regulation of lamellipodium morphogenesis; GO:0010632 regulation of epithelial cell migration; GO:0080090 regulation of primary metabolic process; GO:0031346 positive regulation of cell projection organization; GO:0044763 single-organism cellular process; GO:1903392 negative regulation of adherens junction organization; GO:0048870 cell motility; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:2000146 negative regulation of cell motility; GO:1901888 regulation of cell junction assembly; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:1902745 positive regulation of lamellipodium organization; GO:0048513 animal organ development; GO:0051336 regulation of hydrolase activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0010721 negative regulation of cell development; GO:0051094 positive regulation of developmental process; GO:2000392 regulation of lamellipodium morphogenesis; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0001952 regulation of cell-matrix adhesion; GO:0007162 negative regulation of cell adhesion; GO:0031399 regulation of protein modification process; GO:1901889 negative regulation of cell junction assembly; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0051239 regulation of multicellular organismal process; GO:1902578 single-organism localization; GO:0051345 positive regulation of hydrolase activity; GO:2000145 regulation of cell motility; GO:0051338 regulation of transferase activity; GO:1900024 regulation of substrate adhesion-dependent cell spreading; GO:0001933 negative regulation of protein phosphorylation; GO:0007275 multicellular organism development; GO:0001953 negative regulation of cell-matrix adhesion; GO:0007010 cytoskeleton organization; GO:0010771 negative regulation of cell morphogenesis involved in differentiation; GO:0060485 mesenchyme development; GO:0051270 regulation of cellular component movement; GO:0043547 positive regulation of GTPase activity; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0060284 regulation of cell development; GO:1900027 regulation of ruffle assembly; GO:0030334 regulation of cell migration; GO:0009892 negative regulation of metabolic process; GO:0030155 regulation of cell adhesion; GO:0045184 establishment of protein localization; GO:0014032 neural crest cell development; GO:0014033 neural crest cell differentiation; GO:0030336 negative regulation of cell migration; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0048863 stem cell differentiation; GO:0006928 movement of cell or subcellular component; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:0010810 regulation of cell-substrate adhesion; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0045936 negative regulation of phosphate metabolic process; GO:0051093 negative regulation of developmental process; GO:1903391 regulation of adherens junction organization; GO:0051674 localization of cell; GO:0010633 negative regulation of epithelial cell migration; GO:0051129 negative regulation of cellular component organization; GO:0048869 cellular developmental process; GO:0051241 negative regulation of multicellular organismal process; GO:0090109 regulation of cell-substrate junction assembly; GO:0044699 single-organism process; GO:0031400 negative regulation of protein modification process; GO:0006909 phagocytosis; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0040013 negative regulation of locomotion; GO:1900025 negative regulation of substrate adhesion-dependent cell spreading; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0033673 negative regulation of kinase activity; GO:0033036 macromolecule localization; GO:0045596 negative regulation of cell differentiation; GO:0032502 developmental process; GO:0009888 tissue development; GO:0048522 positive regulation of cellular process; GO:0051348 negative regulation of transferase activity; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0051895 negative regulation of focal adhesion assembly; GO:0001667 ameboidal-type cell migration; GO:0006469 negative regulation of protein kinase activity; GO:0065009 regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0040011 locomotion; GO:0019220 regulation of phosphate metabolic process; GO:0010812 negative regulation of cell-substrate adhesion; GO:0048856 anatomical structure development; GO:0043549 regulation of kinase activity; GO:0051271 negative regulation of cellular component movement; GO:0045859 regulation of protein kinase activity; GO:0016043 cellular component organization; GO:0016477 cell migration; GO:0014031 mesenchymal cell development; GO:0060255 regulation of macromolecule metabolic process; GO:0051893 regulation of focal adhesion assembly; GO:0031344 regulation of cell projection organization; GO:0044087 regulation of cellular component biogenesis; GO:0048864 stem cell development; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0090630 activation of GTPase activity; GO:0030154 cell differentiation; GO:1902743 regulation of lamellipodium organization; GO:0042326 negative regulation of phosphorylation; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0001932 regulation of protein phosphorylation; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0010563 negative regulation of phosphorus metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0051128 regulation of cellular component organization; GO:0040012 regulation of locomotion; GO:0022604 regulation of cell morphogenesis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; GO:0048762 mesenchymal cell differentiation; ","GO:0016020 membrane; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0098857 membrane microdomain; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0098590 plasma membrane region; GO:0005925 focal adhesion; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0098589 membrane region; GO:0030027 lamellipodium; GO:0005912 adherens junction; GO:0030055 cell-substrate junction; GO:0045121 membrane raft; GO:0016600 flotillin complex; GO:0005924 cell-substrate adherens junction; GO:0043229 intracellular organelle; GO:0031252 cell leading edge; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0098797 plasma membrane protein complex; GO:0070161 anchoring junction; GO:0005901 caveola; GO:0015629 actin cytoskeleton; GO:0016328 lateral plasma membrane; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0044853 plasma membrane raft; GO:0043234 protein complex; ","GO:0031267 small GTPase binding; GO:0051015 actin filament binding; GO:0017048 Rho GTPase binding; GO:0048365 Rac GTPase binding; GO:0008092 cytoskeletal protein binding; GO:0017016 Ras GTPase binding; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0003779 actin binding; GO:0005515 protein binding; GO:0051020 GTPase binding; GO:0019899 enzyme binding; GO:0032403 protein complex binding; ","K13886",null,null,"IPR017986; IPR015943; IPR015048; ","WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain; Domain of unknown function DUF1899; \r"]
["Q9ULZ3","Apoptosis-associated speck-like protein containing a CARD OS=Homo sapiens OX=9606 GN=PYCARD","PYCARD",21.627,52.604,36.9,7,15,7,0.812,0.856,0.833,1.17,1.108,1.147,1.369,0.00014,"nucleus\r",{"$cut":{"chars":19503,"head":"GO:0044700 single organism signaling; GO:0002694 regulation of leukocyte activation; GO:0010941 regulation of cell death; GO:0032872 regulation of stress-activated MAPK cascade; GO:0032680 regulation of tumor necrosis factor production; GO:0098542 defense response to other organism; GO:0002586 regulation of antigen processing and presentation of peptide antigen via MHC class II; GO:0070555 response to interleukin-1; GO:0031347 regulation of defense response; GO:0010821 regulation of mitochondrion organization; GO:0032088 negative regulation of NF-kappaB transcription factor activity; GO:0009607 response to biotic stimulus; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0032732 positive regulation of interleukin-1 production; GO:0032946 positive regulation of mononuclear cell proliferation; GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling; GO:0032535 regulation of cellular component size; GO:0044093 positive regulation of molecular function; GO:0051493 regulation of cytoskeleton organization; GO:0052548 regulation of endopeptidase activity; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0010950 positive regulation of endopeptidase activity; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0046006 regulation of activated T cell proliferation; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0043086 negative regulation of catalytic activity; GO:0071396 cellular response to lipid; GO:0033209 tumor necrosis factor-mediated signaling pathway; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0001773 myeloid dendritic cell activation; GO:0051092 positive regulation of NF-kappaB transcription factor activity; GO:1902532 negative regulation of intracellular signal transduction; GO:0080135 regulation of cellular response to stress; GO:0032874 positive regulation of stress-activated MAPK cascade; GO:0048583 regulation of response to stimulus; GO:1902905 positive regulation of supramolecular fiber organization; GO:0051223 regulation of protein transport; GO:0002687 positive regulation of leukocyte migration; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0032677 regulation of interleukin-8 production; GO:0097190 apoptotic signaling pathway; GO:2001056 positive regulation of cysteine-type endopeptidase activity; GO:0001819 positive regulation of cytokine production; GO:1901700 response to oxygen-containing compound; GO:0048519 negative regulation of biological process; GO:0002579 positive regulation of antigen processing and presentation; GO:2000778 positive regulation of interleukin-6 secretion; GO:0050718 positive regulation of interleukin-1 beta secretion; GO:0050867 positive regulation of cell activation; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0051345 positive regulation of hydrolase activity; GO:0050716 positive regulation of interleukin-1 secretion; GO:2000145 regulation of cell motility; GO:0009889 regulation of biosynthetic process; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:2000403 positive regulation of lymphocyte migration; GO:0090196 regulation of chemokine secretion; GO:0050778 positive regulation of immune response; GO:0030100 regulation of endocytosis; GO:0045785 positive regulation of cell adhesion; GO:0006950 response to stress; GO:0032648 regulation of interferon-beta production; GO:0051270 regulation of cellular component movement; GO:0032496 response to lipopolysaccharide; GO:0072331 signal transduction by p53 class mediator; GO:0050766 positive regulation of phagocytosis; GO:0032970 regulation of actin filament-based process; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:1903039 positive regulation of leukocyte cell-cell adhesion; GO:0002263 cell activation involved in immune response;"}},"GO:0034774 secretory granule lumen; GO:0005783 endoplasmic reticulum; GO:0061695 transferase complex, transferring phosphorus-containing groups; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0008385 IkappaB kinase complex; GO:0032991 macromolecular complex; GO:0072559 NLRP3 inflammasome complex; GO:0044424 intracellular part; GO:0035578 azurophil granule lumen; GO:0061702 inflammasome complex; GO:1902554 serine/threonine protein kinase complex; GO:0072558 NLRP1 inflammasome complex; GO:0005623 cell; GO:1902911 protein kinase complex; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005775 vacuolar lumen; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:0030141 secretory granule; GO:0044445 cytosolic part; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097169 AIM2 inflammasome complex; GO:0000323 lytic vacuole; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0005730 nucleolus; GO:1990234 transferase complex; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0042582 azurophil granule; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0008233 peptidase activity; GO:0005102 receptor binding; GO:0061134 peptidase regulator activity; GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process; GO:0046983 protein dimerization activity; GO:0070700 BMP receptor binding; GO:0016504 peptidase activator activity; GO:0008234 cysteine-type peptidase activity; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0017024 myosin I binding; GO:0033612 receptor serine/threonine kinase binding; GO:0008092 cytoskeletal protein binding; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0004197 cysteine-type endopeptidase activity; GO:0016505 peptidase activator activity involved in apoptotic process; GO:0008047 enzyme activator activity; GO:0005126 cytokine receptor binding; GO:0005138 interleukin-6 receptor binding; GO:0070851 growth factor receptor binding; GO:0005523 tropomyosin binding; GO:0004175 endopeptidase activity; GO:0002020 protease binding; GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process; GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process; GO:0030234 enzyme regulator activity; GO:0042803 protein homodimerization activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0019904 protein domain specific binding; GO:0017022 myosin binding; GO:0032090 Pyrin domain binding; GO:0070696 transmembrane receptor protein serine/threonine kinase binding; GO:0019899 enzyme binding; ","K12799","PYCARD; apoptosis-associated speck-like protein containing a CARD","hsa05132 Salmonella infection - Homo sapiens (human); hsa04625 C-type lectin receptor signaling pathway - Homo sapiens (human); hsa04217 Necroptosis - Homo sapiens (human); hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human); hsa04623 Cytosolic DNA-sensing pathway - Homo sapiens (human); hsa05133 Pertussis - Homo sapiens (human); hsa05134 Legionellosis - Homo sapiens (human); hsa05164 Influenza A - Homo sapiens (human); ","IPR004020; IPR011029; IPR033516; IPR001315; ","\"DAPIN domain; Death-like domain; CARD8/ASC/NALP1, CARD domain; CARD domain; \"\r"]
["Q9UM54","Unconventional myosin-VI OS=Homo sapiens OX=9606 GN=MYO6","MYO6",149.69,7.447,2.6,3,4,3,0.982,1.329,1.085,0.845,0.788,0.997,0.774,0.0893,"cytoplasm\r","GO:0044700 single organism signaling; GO:0030048 actin filament-based movement; GO:0009891 positive regulation of biosynthetic process; GO:0044699 single-organism process; GO:0051046 regulation of secretion; GO:0050877 neurological system process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0032879 regulation of localization; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0010468 regulation of gene expression; GO:0051716 cellular response to stimulus; GO:0007600 sensory perception; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0031323 regulation of cellular metabolic process; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0050954 sensory perception of mechanical stimulus; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0046907 intracellular transport; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0050896 response to stimulus; GO:0030330 DNA damage response, signal transduction by p53 class mediator; GO:0042493 response to drug; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0006886 intracellular protein transport; GO:0051171 regulation of nitrogen compound metabolic process; GO:0042770 signal transduction in response to DNA damage; GO:1902680 positive regulation of RNA biosynthetic process; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0051254 positive regulation of RNA metabolic process; GO:0003008 system process; GO:0006355 regulation of transcription, DNA-templated; GO:0006950 response to stress; GO:0035556 intracellular signal transduction; GO:0051049 regulation of transport; GO:0016192 vesicle-mediated transport; GO:0072331 signal transduction by p53 class mediator; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0071702 organic substance transport; GO:0010556 regulation of macromolecule biosynthetic process; GO:0006897 endocytosis; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0006974 cellular response to DNA damage stimulus; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0031325 positive regulation of cellular metabolic process; GO:0030029 actin filament-based process; GO:0006928 movement of cell or subcellular component; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0007605 sensory perception of sound; GO:0031328 positive regulation of cellular biosynthetic process; GO:0051179 localization; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0032587 ruffle membrane; GO:0005737 cytoplasm; GO:0099568 cytoplasmic region; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0098858 actin-based cell projection; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005765 lysosomal membrane; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0031965 nuclear membrane; GO:0098590 plasma membrane region; GO:0030136 clathrin-coated vesicle; GO:0031256 leading edge membrane; GO:0005622 intracellular; GO:0005764 lysosome; GO:0098589 membrane region; GO:0016459 myosin complex; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0045177 apical part of cell; GO:0043233 organelle lumen; GO:0031941 filamentous actin; GO:0000323 lytic vacuole; GO:0031252 cell leading edge; GO:0055029 nuclear DNA-directed RNA polymerase complex; GO:0099513 polymeric cytoskeletal fiber; GO:0042995 cell projection; GO:0044430 cytoskeletal part; GO:0031967 organelle envelope; GO:0030880 RNA polymerase complex; GO:0012506 vesicle membrane; GO:0031981 nuclear lumen; GO:0030135 coated vesicle; GO:0005576 extracellular region; GO:0016591 DNA-directed RNA polymerase II, holoenzyme; GO:0016461 unconventional myosin complex; GO:0099081 supramolecular polymer; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0031975 envelope; GO:0044437 vacuolar part; GO:0005902 microvillus; GO:0005773 vacuole; GO:0005905 clathrin-coated pit; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0061695 transferase complex, transferring phosphorus-containing groups; GO:0005938 cell cortex; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0030662 coated vesicle membrane; GO:0005856 cytoskeleton; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0005884 actin filament; GO:0030139 endocytic vesicle; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0000428 DNA-directed RNA polymerase complex; GO:0098588 bounding membrane of organelle; GO:0005635 nuclear envelope; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:1990234 transferase complex; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0030665 clathrin-coated vesicle membrane; GO:0015629 actin cytoskeleton; GO:0030659 cytoplasmic vesicle membrane; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0001726 ruffle; GO:0031253 cell projection membrane; GO:0005774 vacuolar membrane; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0051015 actin filament binding; GO:1901265 nucleoside phosphate binding; GO:0003774 motor activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0008092 cytoskeletal protein binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0060001 minus-end directed microfilament motor activity; GO:0032550 purine ribonucleoside binding; GO:0045296 cadherin binding; GO:0043531 ADP binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0000146 microfilament motor activity; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0035639 purine ribonucleoside triphosphate binding; GO:0017076 purine nucleotide binding; GO:0005524 ATP binding; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0005516 calmodulin binding; GO:0050839 cell adhesion molecule binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003779 actin binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; GO:0032403 protein complex binding; ","K10358",null,null,"IPR027417; IPR001609; IPR032412; ","\"P-loop containing nucleoside triphosphate hydrolase; Myosin head, motor domain; Myosin VI, cargo binding domain; \"\r"]
["Q9UMD9","Collagen alpha-1(XVII) chain OS=Homo sapiens OX=9606 GN=COL17A1","COL17A1",150.42,14.518,4.7,8,8,8,0.944,0.912,0.885,1.121,1.048,1.094,1.19,0.00302,"cytoplasm\r","GO:0032502 developmental process; GO:0044085 cellular component biogenesis; GO:0016043 cellular component organization; GO:0034329 cell junction assembly; GO:0007044 cell-substrate junction assembly; GO:0009888 tissue development; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0050776 regulation of immune response; GO:0022610 biological adhesion; GO:0050789 regulation of biological process; GO:0034330 cell junction organization; GO:0031589 cell-substrate adhesion; GO:0022607 cellular component assembly; GO:0031581 hemidesmosome assembly; GO:0048583 regulation of response to stimulus; GO:0007160 cell-matrix adhesion; GO:0008544 epidermis development; GO:0007155 cell adhesion; GO:0002682 regulation of immune system process; GO:0048856 anatomical structure development; GO:0009987 cellular process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005911 cell-cell junction; GO:0005623 cell; GO:0044420 extracellular matrix component; GO:0005581 collagen trimer; GO:0044422 organelle part; GO:0005604 basement membrane; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0030055 cell-substrate junction; GO:0030056 hemidesmosome; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005788 endoplasmic reticulum lumen; GO:0031226 intrinsic component of plasma membrane; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0031012 extracellular matrix; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0044432 endoplasmic reticulum part; GO:0005578 proteinaceous extracellular matrix; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ","K07603","COL17A; collagen, type XVII, alpha","hsa04974 Protein digestion and absorption - Homo sapiens (human); "]
["Q9UMR5","Lysosomal thioesterase PPT2 OS=Homo sapiens OX=9606 GN=PPT2","PPT2",34.225,5.0943,4.6,1,1,1,0.982,0.887,1.034,1.011,0.991,1.095,1.067,0.293,"extracellular\r","GO:0006790 sulfur compound metabolic process; GO:0051188 cofactor biosynthetic process; GO:0046949 fatty-acyl-CoA biosynthetic process; GO:0071616 acyl-CoA biosynthetic process; GO:0035337 fatty-acyl-CoA metabolic process; GO:0035383 thioester metabolic process; GO:0098734 macromolecule depalmitoylation; GO:0006732 coenzyme metabolic process; GO:0035336 long-chain fatty-acyl-CoA metabolic process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0035338 long-chain fatty-acyl-CoA biosynthetic process; GO:1901576 organic substance biosynthetic process; GO:0006637 acyl-CoA metabolic process; GO:0044249 cellular biosynthetic process; GO:0035384 thioester biosynthetic process; GO:0044272 sulfur compound biosynthetic process; GO:0051186 cofactor metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0006793 phosphorus metabolic process; GO:0009108 coenzyme biosynthetic process; GO:0043170 macromolecule metabolic process; GO:0043412 macromolecule modification; GO:0009987 cellular process; GO:0098732 macromolecule deacylation; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0043202 lysosomal lumen; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0044437 vacuolar part; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0005773 vacuole; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0000323 lytic vacuole; ","GO:0098599 palmitoyl hydrolase activity; GO:0016787 hydrolase activity; GO:0008474 palmitoyl-(protein) hydrolase activity; GO:0016790 thiolester hydrolase activity; GO:0003824 catalytic activity; GO:0016788 hydrolase activity, acting on ester bonds; ","K01074","PPT; palmitoyl-protein thioesterase [EC:3.1.2.22]","hsa04142 Lysosome - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa01212 Fatty acid metabolism - Homo sapiens (human); hsa00062 Fatty acid elongation - Homo sapiens (human); ","IPR029058; ","Alpha/Beta hydrolase fold; \r"]
["Q9UMS0","NFU1 iron-sulfur cluster scaffold homolog, mitochondrial OS=Homo sapiens OX=9606 GN=NFU1","NFU1",28.462,17.383,9.1,2,2,2,0.973,1.048,1.052,0.956,0.947,1.033,0.955,0.289,"mitochondria\r","GO:0006790 sulfur compound metabolic process; GO:0044085 cellular component biogenesis; GO:0051188 cofactor biosynthetic process; GO:0016043 cellular component organization; GO:0008152 metabolic process; GO:0031163 metallo-sulfur cluster assembly; GO:0022607 cellular component assembly; GO:0016226 iron-sulfur cluster assembly; GO:0009058 biosynthetic process; GO:0009987 cellular process; GO:0044237 cellular metabolic process; GO:0044249 cellular biosynthetic process; GO:0071840 cellular component organization or biogenesis; GO:0051186 cofactor metabolic process; ","GO:0043229 intracellular organelle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0005506 iron ion binding; GO:0046914 transition metal ion binding; GO:0051536 iron-sulfur cluster binding; GO:0005488 binding; GO:0043167 ion binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0051539 4 iron, 4 sulfur cluster binding; GO:0051540 metal cluster binding; ",{"$nulls":3},"IPR001075; IPR014824; ","\"NIF system FeS cluster assembly, NifU, C-terminal; Scaffold protein Nfu/NifU, N-terminal; \"\r"]
["Q9UMS4","Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19","PRPF19",55.18,10.058,6.7,4,4,4,0.92,0.898,0.932,1.125,1.043,1.044,1.168,0.0048,"cytoplasm\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0014013 regulation of gliogenesis; GO:0022618 ribonucleoprotein complex assembly; GO:0043009 chordate embryonic development; GO:0006289 nucleotide-excision repair; GO:0044237 cellular metabolic process; GO:0048710 regulation of astrocyte differentiation; GO:0008610 lipid biosynthetic process; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0065003 macromolecular complex assembly; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0008104 protein localization; GO:0009790 embryo development; GO:0000393 spliceosomal conformational changes to generate catalytic conformation; GO:0007399 nervous system development; GO:0006396 RNA processing; GO:0000349 generation of catalytic spliceosome for first transesterification step; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0050684 regulation of mRNA processing; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0050768 negative regulation of neurogenesis; GO:1901575 organic substance catabolic process; GO:0001701 in utero embryonic development; GO:0044710 single-organism metabolic process; GO:0030163 protein catabolic process; GO:0045665 negative regulation of neuron differentiation; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0010721 negative regulation of cell development; GO:0051094 positive regulation of developmental process; GO:0016071 mRNA metabolic process; GO:0001832 blastocyst growth; GO:0033120 positive regulation of RNA splicing; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0044707 single-multicellular organism process; GO:0006283 transcription-coupled nucleotide-excision repair; GO:0006259 DNA metabolic process; GO:0044267 cellular protein metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0045597 positive regulation of cell differentiation; GO:0051239 regulation of multicellular organismal process; GO:0000209 protein polyubiquitination; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0010628 positive regulation of gene expression; GO:0000375 RNA splicing, via transesterification reactions; GO:0051171 regulation of nitrogen compound metabolic process; GO:0044248 cellular catabolic process; GO:0007275 multicellular organism development; GO:0034613 cellular protein localization; GO:0008380 RNA splicing; GO:0051254 positive regulation of RNA metabolic process; GO:0006950 response to stress; GO:0016567 protein ubiquitination; GO:0044711 single-organism biosynthetic process; GO:0048731 system development; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0001824 blastocyst development; GO:0008283 cell proliferation; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0006974 cellular response to DNA damage stimulus; GO:0045685 regulation of glial cell differentiation; GO:0043484 regulation of RNA splicing; GO:1903311 regulation of mRNA metabolic process; GO:0032446 protein modification by small protein conjugation; GO:0031325 positive regulation of cellular metabolic process; GO:0050769 positive regulation of neurogenesis; GO:0051179 localization; GO:0048589 developmental growth; GO:0043412 macromolecule modification; GO:0000245 spliceosomal complex assembly; GO:0050793 regulation of developmental process; GO:0040007 growth; GO:0000387 spliceosomal snRNP assembly; GO:0051093 negative regulation of developmental process; GO:0048869 cellular developmental process; GO:0022008 neurogenesis; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0045687 positive regulation of glial cell differentiation; GO:0007165 signal transduction; GO:0000077 DNA damage checkpoint; GO:0071826 ribonucleoprotein complex subunit organization; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0022607 cellular component assembly; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0000075 cell cycle checkpoint; GO:0001833 inner cell mass cell proliferation; GO:0010720 positive regulation of cell development; GO:0045596 negative regulation of cell differentiation; GO:0033036 macromolecule localization; GO:0051726 regulation of cell cycle; GO:0048024 regulation of mRNA splicing, via spliceosome; GO:0006629 lipid metabolic process; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0051962 positive regulation of nervous system development; GO:0031570 DNA integrity checkpoint; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0070647 protein modification by small protein conjugation or removal; GO:0023052 signaling; GO:1903313 positive regulation of mRNA metabolic process; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0045664 regulation of neuron differentiation; GO:0019222 regulation of metabolic process; GO:0048711 positive regulation of astrocyte differentiation; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0006303 double-strand break repair via nonhomologous end joining; GO:0072401 signal transduction involved in DNA integrity checkpoint; GO:2000026 regulation of multicellular organismal development; GO:0070534 protein K63-linked ubiquitination; GO:0016043 cellular component organization; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0045786 negative regulation of cell cycle; GO:0072395 signal transduction involved in cell cycle checkpoint; GO:0044257 cellular protein catabolic process; GO:0050685 positive regulation of mRNA processing; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0006302 double-strand break repair; GO:0050896 response to stimulus; GO:0010498 proteasomal protein catabolic process; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0000398 mRNA splicing, via spliceosome; GO:0051961 negative regulation of nervous system development; GO:0006508 proteolysis; GO:0034641 cellular nitrogen compound metabolic process; GO:0042770 signal transduction in response to DNA damage; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0034622 cellular macromolecular complex assembly; GO:0044265 cellular macromolecule catabolic process; GO:0072422 signal transduction involved in DNA damage checkpoint; GO:0035556 intracellular signal transduction; GO:0000726 non-recombinational repair; GO:0009792 embryo development ending in birth or egg hatching; GO:0006807 nitrogen compound metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0043933 macromolecular complex subunit organization; GO:0000244 spliceosomal tri-snRNP complex assembly; GO:0014015 positive regulation of gliogenesis; GO:0006281 DNA repair; GO:0070727 cellular macromolecule localization; GO:0044767 single-organism developmental process; GO:0009057 macromolecule catabolic process; GO:0048026 positive regulation of mRNA splicing, via spliceosome; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0010467 gene expression; GO:0009056 catabolic process; GO:0050767 regulation of neurogenesis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0000974 Prp19 complex; GO:0005737 cytoplasm; GO:0005684 U2-type spliceosomal complex; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0071012 catalytic step 1 spliceosome; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0016607 nuclear speck; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0005811 lipid particle; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0071006 U2-type catalytic step 1 spliceosome; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005681 spliceosomal complex; GO:0005819 spindle; GO:0090734 site of DNA damage; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0071013 catalytic step 2 spliceosome; GO:0035861 site of double-strand break; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043234 protein complex; GO:0044428 nuclear part; ","GO:0061630 ubiquitin protein ligase activity; GO:0042802 identical protein binding; GO:0019787 ubiquitin-like protein transferase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0004842 ubiquitin-protein transferase activity; GO:0034450 ubiquitin-ubiquitin ligase activity; GO:0005515 protein binding; GO:0061659 ubiquitin-like protein ligase activity; GO:0016740 transferase activity; ","K10599","PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]","hsa03040 Spliceosome - Homo sapiens (human); hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human); ","IPR003613; IPR013083; IPR017986; IPR015943; IPR000772; IPR013915; ","\"U box domain; Zinc finger, RING/FYVE/PHD-type; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain; Ricin B, lectin domain; Pre-mRNA-splicing factor 19; \"\r"]
["Q9UMS6","Synaptopodin-2 OS=Homo sapiens OX=9606 GN=SYNPO2","SYNPO2",117.51,46.546,6,7,9,7,0.978,1.045,1.051,0.962,1.001,0.936,0.943,0.125,"nucleus\r","GO:0050794 regulation of cellular process; GO:0051495 positive regulation of cytoskeleton organization; GO:0032956 regulation of actin cytoskeleton organization; GO:0032231 regulation of actin filament bundle assembly; GO:0048522 positive regulation of cellular process; GO:0033043 regulation of organelle organization; GO:0044087 regulation of cellular component biogenesis; GO:0032970 regulation of actin filament-based process; GO:0048518 positive regulation of biological process; GO:0051130 positive regulation of cellular component organization; GO:0050789 regulation of biological process; GO:0010638 positive regulation of organelle organization; GO:1902905 positive regulation of supramolecular fiber organization; GO:0032233 positive regulation of actin filament bundle assembly; GO:0051128 regulation of cellular component organization; GO:0051493 regulation of cytoskeleton organization; GO:0044089 positive regulation of cellular component biogenesis; GO:1902903 regulation of supramolecular fiber organization; GO:0065007 biological regulation; ","GO:0030054 cell junction; GO:0030016 myofibril; GO:0005737 cytoplasm; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0030018 Z disc; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0031674 I band; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0044464 cell part; GO:0043292 contractile fiber; GO:0005912 adherens junction; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0070161 anchoring junction; GO:0005829 cytosol; GO:0015629 actin cytoskeleton; GO:0099081 supramolecular polymer; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0030017 sarcomere; GO:0044449 contractile fiber part; GO:0044444 cytoplasmic part; ","GO:0008092 cytoskeletal protein binding; GO:0005488 binding; GO:0042805 actinin binding; GO:0003779 actin binding; GO:0071889 14-3-3 protein binding; GO:0005515 protein binding; GO:0051393 alpha-actinin binding; GO:0051371 muscle alpha-actinin binding; ",{"$nulls":3},"IPR001478; ","PDZ domain; \r"]
["Q9UMX0","Ubiquilin-1 OS=Homo sapiens OX=9606 GN=UBQLN1","UBQLN1",62.518,23.695,13.1,5,6,3,0.82,1.185,0.872,0.999,0.999,1.131,1.088,0.474,"nucleus\r","GO:0044085 cellular component biogenesis; GO:1905037 autophagosome organization; GO:0010941 regulation of cell death; GO:0032270 positive regulation of cellular protein metabolic process; GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0036503 ERAD pathway; GO:1903170 negative regulation of calcium ion transmembrane transport; GO:0031347 regulation of defense response; GO:1905897 regulation of response to endoplasmic reticulum stress; GO:0006914 autophagy; GO:0044237 cellular metabolic process; GO:1903364 positive regulation of cellular protein catabolic process; GO:0008152 metabolic process; GO:0032879 regulation of localization; GO:1901019 regulation of calcium ion transmembrane transporter activity; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:1901339 regulation of store-operated calcium channel activity; GO:1903362 regulation of cellular protein catabolic process; GO:1901020 negative regulation of calcium ion transmembrane transporter activity; GO:1905898 positive regulation of response to endoplasmic reticulum stress; GO:0051051 negative regulation of transport; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0035973 aggrephagy; GO:0009894 regulation of catabolic process; GO:0043269 regulation of ion transport; GO:0044763 single-organism cellular process; GO:0031323 regulation of cellular metabolic process; GO:0050776 regulation of immune response; GO:0034762 regulation of transmembrane transport; GO:1901575 organic substance catabolic process; GO:0080135 regulation of cellular response to stress; GO:0044710 single-organism metabolic process; GO:0030163 protein catabolic process; GO:0061136 regulation of proteasomal protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:2001257 regulation of cation channel activity; GO:0010604 positive regulation of macromolecule metabolic process; GO:0002682 regulation of immune system process; GO:0032412 regulation of ion transmembrane transporter activity; GO:0000045 autophagosome assembly; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0034976 response to endoplasmic reticulum stress; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0043067 regulation of programmed cell death; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0080134 regulation of response to stress; GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:1901340 negative regulation of store-operated calcium channel activity; GO:0009896 positive regulation of catabolic process; GO:0070482 response to oxygen levels; GO:0010959 regulation of metal ion transport; GO:0044248 cellular catabolic process; GO:0042176 regulation of protein catabolic process; GO:0009966 regulation of signal transduction; GO:0032409 regulation of transporter activity; GO:1904062 regulation of cation transmembrane transport; GO:0071456 cellular response to hypoxia; GO:0034763 negative regulation of transmembrane transport; GO:1904292 regulation of ERAD pathway; GO:1902531 regulation of intracellular signal transduction; GO:0006950 response to stress; GO:0051926 negative regulation of calcium ion transport; GO:0051924 regulation of calcium ion transport; GO:0048284 organelle fusion; GO:0030162 regulation of proteolysis; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0034766 negative regulation of ion transmembrane transport; GO:0051247 positive regulation of protein metabolic process; GO:0031398 positive regulation of protein ubiquitination; GO:0097576 vacuole fusion; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:1902882 regulation of response to oxidative stress; GO:0036293 response to decreased oxygen levels; GO:1904294 positive regulation of ERAD pathway; GO:0048584 positive regulation of response to stimulus; GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process; GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0031331 positive regulation of cellular catabolic process; GO:0044699 single-organism process; GO:0031396 regulation of protein ubiquitination; GO:2001233 regulation of apoptotic signaling pathway; GO:0010646 regulation of cell communication; GO:0030433 ubiquitin-dependent ERAD pathway; GO:0045088 regulation of innate immune response; GO:0022607 cellular component assembly; GO:0009893 positive regulation of metabolic process; GO:0007033 vacuole organization; GO:2001258 negative regulation of cation channel activity; GO:0032413 negative regulation of ion transmembrane transporter activity; GO:0070887 cellular response to chemical stimulus; GO:0016236 macroautophagy; GO:0034121 regulation of toll-like receptor signaling pathway; GO:0048522 positive regulation of cellular process; GO:0022898 regulation of transmembrane transporter activity; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0002683 negative regulation of immune system process; GO:1902589 single-organism organelle organization; GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0032268 regulation of cellular protein metabolic process; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0016043 cellular component organization; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:0034122 negative regulation of toll-like receptor signaling pathway; GO:0060255 regulation of macromolecule metabolic process; GO:0097352 autophagosome maturation; GO:1903201 regulation of oxidative stress-induced cell death; GO:0050896 response to stimulus; GO:0010498 proteasomal protein catabolic process; GO:0071704 organic substance metabolic process; GO:1903322 positive regulation of protein modification by small protein conjugation or removal; GO:0045862 positive regulation of proteolysis; GO:0070925 organelle assembly; GO:0001666 response to hypoxia; GO:1903169 regulation of calcium ion transmembrane transport; GO:0032410 negative regulation of transporter activity; GO:0006508 proteolysis; GO:0071453 cellular response to oxygen levels; GO:0009987 cellular process; GO:0034140 negative regulation of toll-like receptor 3 signaling pathway; GO:0043632 modification-dependent macromolecule catabolic process; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0043271 negative regulation of ion transport; GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway; GO:0019941 modification-dependent protein catabolic process; GO:0051049 regulation of transport; GO:0044712 single-organism catabolic process; GO:1901800 positive regulation of proteasomal protein catabolic process; GO:0031401 positive regulation of protein modification process; GO:0048585 negative regulation of response to stimulus; GO:0048518 positive regulation of biological process; GO:1904063 negative regulation of cation transmembrane transport; GO:1900407 regulation of cellular response to oxidative stress; GO:0034765 regulation of ion transmembrane transport; GO:0051246 regulation of protein metabolic process; GO:2001242 regulation of intrinsic apoptotic signaling pathway; GO:0009057 macromolecule catabolic process; GO:0034139 regulation of toll-like receptor 3 signaling pathway; GO:0045732 positive regulation of protein catabolic process; GO:0009056 catabolic process; GO:0042981 regulation of apoptotic process; GO:0036294 cellular response to decreased oxygen levels; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005776 autophagosome; GO:1905369 endopeptidase complex; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0048471 perinuclear region of cytoplasm; GO:1905368 peptidase complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0000502 proteasome complex; GO:0016234 inclusion body; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0016235 aggresome; GO:0005773 vacuole; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0031593 polyubiquitin binding; GO:0042802 identical protein binding; GO:0005488 binding; GO:0043130 ubiquitin binding; GO:0005515 protein binding; GO:0019900 kinase binding; GO:0032182 ubiquitin-like protein binding; GO:0019899 enzyme binding; ","K04523","UBQLN; ubiquilin","hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); ","IPR006636; IPR015940; IPR029071; IPR000626; IPR009060; ","Heat shock chaperonin-binding; Ubiquitin-associated domain; Ubiquitin-related domain; Ubiquitin domain; UBA-like; \r"]
["Q9UMY4","Sorting nexin-12 OS=Homo sapiens OX=9606 GN=SNX12","SNX12",19.73,27.07,20.3,4,7,3,1.072,0.972,1.065,1.011,0.96,1.023,0.963,0.375,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0060627 regulation of vesicle-mediated transport; GO:0016043 cellular component organization; GO:0042177 negative regulation of protein catabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0010955 negative regulation of protein processing; GO:1903318 negative regulation of protein maturation; GO:0031324 negative regulation of cellular metabolic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0015031 protein transport; GO:0070201 regulation of establishment of protein localization; GO:0060341 regulation of cellular localization; GO:0051234 establishment of localization; GO:0032879 regulation of localization; GO:2000641 regulation of early endosome to late endosome transport; GO:0009895 negative regulation of catabolic process; GO:0032387 negative regulation of intracellular transport; GO:0032880 regulation of protein localization; GO:0042176 regulation of protein catabolic process; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0009987 cellular process; GO:0051051 negative regulation of transport; GO:0010468 regulation of gene expression; GO:0045861 negative regulation of proteolysis; GO:0030100 regulation of endocytosis; GO:0080090 regulation of primary metabolic process; GO:0051224 negative regulation of protein transport; GO:0010629 negative regulation of gene expression; GO:0051049 regulation of transport; GO:1903649 regulation of cytoplasmic transport; GO:0009894 regulation of catabolic process; GO:0016050 vesicle organization; GO:0032386 regulation of intracellular transport; GO:0071702 organic substance transport; GO:0030162 regulation of proteolysis; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0009892 negative regulation of metabolic process; GO:1903650 negative regulation of cytoplasmic transport; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0006996 organelle organization; GO:0032269 negative regulation of cellular protein metabolic process; GO:0051246 regulation of protein metabolic process; GO:0070613 regulation of protein processing; GO:0019222 regulation of metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:1904950 negative regulation of establishment of protein localization; GO:0051223 regulation of protein transport; GO:1903317 regulation of protein maturation; GO:0051128 regulation of cellular component organization; GO:2000642 negative regulation of early endosome to late endosome transport; GO:0051179 localization; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0019898 extrinsic component of membrane; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0005769 early endosome; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005488 binding; GO:0035091 phosphatidylinositol binding; GO:0005543 phospholipid binding; GO:0043167 ion binding; GO:0008289 lipid binding; GO:0005515 protein binding; GO:0043168 anion binding; GO:0019899 enzyme binding; ","K17918","SNX3_12; sorting nexin-3/12","hsa04144 Endocytosis - Homo sapiens (human); ","IPR001683; ","Phox homologous domain; \r"]
["Q9UN36","Protein NDRG2 OS=Homo sapiens OX=9606 GN=NDRG2","NDRG2",40.798,17.092,15.1,4,6,4,1.039,1.073,1.155,0.898,0.915,0.952,0.846,0.00968,"nucleus\r","GO:0044700 single organism signaling; GO:0009968 negative regulation of signal transduction; GO:0007166 cell surface receptor signaling pathway; GO:0007420 brain development; GO:0023051 regulation of signaling; GO:0048869 cellular developmental process; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0001818 negative regulation of cytokine production; GO:0010574 regulation of vascular endothelial growth factor production; GO:0031400 negative regulation of protein modification process; GO:0008285 negative regulation of cell proliferation; GO:0048857 neural nucleus development; GO:0021762 substantia nigra development; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0060322 head development; GO:0016055 Wnt signaling pathway; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0030901 midbrain development; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:0023052 signaling; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0032501 multicellular organismal process; GO:0198738 cell-cell signaling by wnt; GO:0048513 animal organ development; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0007267 cell-cell signaling; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:1902532 negative regulation of intracellular signal transduction; GO:0032269 negative regulation of cellular protein metabolic process; GO:0007417 central nervous system development; GO:0048583 regulation of response to stimulus; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0048856 anatomical structure development; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0042127 regulation of cell proliferation; GO:0048660 regulation of smooth muscle cell proliferation; GO:0060255 regulation of macromolecule metabolic process; GO:0031399 regulation of protein modification process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:0030154 cell differentiation; GO:0070372 regulation of ERK1 and ERK2 cascade; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0043408 regulation of MAPK cascade; GO:0042326 negative regulation of phosphorylation; GO:0070373 negative regulation of ERK1 and ERK2 cascade; GO:0001933 negative regulation of protein phosphorylation; GO:0007275 multicellular organism development; GO:0090361 regulation of platelet-derived growth factor production; GO:0009987 cellular process; GO:0009966 regulation of signal transduction; GO:1902531 regulation of intracellular signal transduction; GO:0048731 system development; GO:0001932 regulation of protein phosphorylation; GO:0048585 negative regulation of response to stimulus; GO:0009892 negative regulation of metabolic process; GO:0048662 negative regulation of smooth muscle cell proliferation; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0010563 negative regulation of phosphorus metabolic process; GO:0043409 negative regulation of MAPK cascade; GO:0051248 negative regulation of protein metabolic process; GO:0001817 regulation of cytokine production; GO:0045936 negative regulation of phosphate metabolic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0042995 cell projection; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0030426 growth cone; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0030427 site of polarized growth; GO:0005623 cell; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0043005 neuron projection; GO:0005794 Golgi apparatus; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR029058; ","Alpha/Beta hydrolase fold; \r"]
["Q9UN37","Vacuolar protein sorting-associated protein 4A OS=Homo sapiens OX=9606 GN=VPS4A","VPS4A",48.897,16.491,16.7,7,13,3,0.993,0.969,0.963,1.006,1.103,1.032,1.074,0.0716,"cytoplasm\r","GO:0060627 regulation of vesicle-mediated transport; GO:0044085 cellular component biogenesis; GO:0052192 movement in environment of other organism involved in symbiotic interaction; GO:0006914 autophagy; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:1903729 regulation of plasma membrane organization; GO:0008152 metabolic process; GO:0032879 regulation of localization; GO:0036258 multivesicular body assembly; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0044801 single-organism membrane fusion; GO:0008104 protein localization; GO:0044419 interspecies interaction between organisms; GO:0044765 single-organism transport; GO:0051782 negative regulation of cell division; GO:1903543 positive regulation of exosomal secretion; GO:0000278 mitotic cell cycle; GO:0007059 chromosome segregation; GO:0006869 lipid transport; GO:0045921 positive regulation of exocytosis; GO:0039702 viral budding via host ESCRT complex; GO:0044763 single-organism cellular process; GO:0072319 vesicle uncoating; GO:0061025 membrane fusion; GO:1903772 regulation of viral budding via host ESCRT complex; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0010948 negative regulation of cell cycle process; GO:0030163 protein catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006906 vesicle fusion; GO:0051301 cell division; GO:0051047 positive regulation of secretion; GO:0050794 regulation of cellular process; GO:0051640 organelle localization; GO:0046907 intracellular transport; GO:0090174 organelle membrane fusion; GO:0044707 single-multicellular organism process; GO:1903076 regulation of protein localization to plasma membrane; GO:0044267 cellular protein metabolic process; GO:0017157 regulation of exocytosis; GO:0007080 mitotic metaphase plate congression; GO:0000920 cell separation after cytokinesis; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:1903541 regulation of exosomal secretion; GO:1903047 mitotic cell cycle process; GO:0060341 regulation of cellular localization; GO:0052126 movement in host environment; GO:1902578 single-organism localization; GO:0043624 cellular protein complex disassembly; GO:0044248 cellular catabolic process; GO:1902580 single-organism cellular localization; GO:0007275 multicellular organism development; GO:0032880 regulation of protein localization; GO:0043900 regulation of multi-organism process; GO:0016192 vesicle-mediated transport; GO:0032984 macromolecular complex disassembly; GO:0010876 lipid localization; GO:1902188 positive regulation of viral release from host cell; GO:0048284 organelle fusion; GO:0071702 organic substance transport; GO:0051656 establishment of organelle localization; GO:0044238 primary metabolic process; GO:0045184 establishment of protein localization; GO:1902186 regulation of viral release from host cell; GO:0019076 viral release from host cell; GO:0035890 exit from host; GO:0051276 chromosome organization; GO:0006996 organelle organization; GO:0098813 nuclear chromosome segregation; GO:0006900 membrane budding; GO:0061024 membrane organization; GO:0000280 nuclear division; GO:0051179 localization; GO:1903827 regulation of cellular protein localization; GO:0015850 organic hydroxy compound transport; GO:0010256 endomembrane system organization; GO:0030301 cholesterol transport; GO:0040017 positive regulation of locomotion; GO:0007067 mitotic nuclear division; GO:0044699 single-organism process; GO:0051046 regulation of secretion; GO:0044764 multi-organism cellular process; GO:0051234 establishment of localization; GO:0043241 protein complex disassembly; GO:0051130 positive regulation of cellular component organization; GO:1904375 regulation of protein localization to cell periphery; GO:0000819 sister chromatid segregation; GO:0050000 chromosome localization; GO:0032365 intracellular lipid transport; GO:0051649 establishment of localization in cell; GO:1904896 ESCRT complex disassembly; GO:0022607 cellular component assembly; GO:0007033 vacuole organization; GO:0033036 macromolecule localization; GO:0051726 regulation of cell cycle; GO:0016236 macroautophagy; GO:0032502 developmental process; GO:1903774 positive regulation of viral budding via host ESCRT complex; GO:1903902 positive regulation of viral life cycle; GO:0043902 positive regulation of multi-organism process; GO:0071822 protein complex subunit organization; GO:0048522 positive regulation of cellular process; GO:0036257 multivesicular body organization; GO:0006511 ubiquitin-dependent protein catabolic process; GO:1903530 regulation of secretion by cell; GO:1902582 single-organism intracellular transport; GO:0051050 positive regulation of transport; GO:0016197 endosomal transport; GO:1902589 single-organism organelle organization; GO:0051302 regulation of cell division; GO:0050789 regulation of biological process; GO:0010638 positive regulation of organelle organization; GO:1903532 positive regulation of secretion by cell; GO:0032367 intracellular cholesterol transport; GO:0040011 locomotion; GO:0048856 anatomical structure development; GO:0015918 sterol transport; GO:0006997 nucleus organization; GO:0016043 cellular component organization; GO:0045786 negative regulation of cell cycle; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0019068 virion assembly; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0048285 organelle fission; GO:0019058 viral life cycle; GO:1902592 multi-organism membrane budding; GO:0044087 regulation of cellular component biogenesis; GO:0051310 metaphase plate congression; GO:0032465 regulation of cytokinesis; GO:0032366 intracellular sterol transport; GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway; GO:0071704 organic substance metabolic process; GO:1905475 regulation of protein localization to membrane; GO:0009838 abscission; GO:0070925 organelle assembly; GO:0016032 viral process; GO:0006508 proteolysis; GO:0009987 cellular process; GO:0034058 endosomal vesicle fusion; GO:0061738 late endosomal microautophagy; GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; GO:0035891 exit from host cell; GO:0051261 protein depolymerization; GO:0043632 modification-dependent macromolecule catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0044803 multi-organism membrane organization; GO:0051303 establishment of chromosome localization; GO:0019941 modification-dependent protein catabolic process; GO:0051049 regulation of transport; GO:0050792 regulation of viral process; GO:0033043 regulation of organelle organization; GO:0000070 mitotic sister chromatid segregation; GO:0016050 vesicle organization; GO:0044802 single-organism membrane organization; GO:0051701 interaction with host; GO:1902590 multi-organism organelle organization; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0043933 macromolecular complex subunit organization; GO:0048524 positive regulation of viral process; GO:0046755 viral budding; GO:0044767 single-organism developmental process; GO:0009057 macromolecule catabolic process; GO:1904903 ESCRT III complex disassembly; GO:0022411 cellular component disassembly; GO:0022402 cell cycle process; GO:0051128 regulation of cellular component organization; GO:0032466 negative regulation of cytokinesis; GO:0040012 regulation of locomotion; GO:1903900 regulation of viral life cycle; GO:0009056 catabolic process; GO:0007032 endosome organization; GO:0007049 cell cycle; GO:0044089 positive regulation of cellular component biogenesis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0005815 microtubule organizing center; GO:0015630 microtubule cytoskeleton; GO:0031902 late endosome membrane; GO:0005622 intracellular; GO:0044464 cell part; GO:0005764 lysosome; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0090543 Flemming body; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0010008 endosome membrane; GO:0000922 spindle pole; GO:0005770 late endosome; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0030496 midbody; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0005829 cytosol; GO:0005819 spindle; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005813 centrosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0016887 ATPase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0008022 protein C-terminus binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0042623 ATPase activity, coupled; GO:0032555 purine ribonucleotide binding; GO:0019904 protein domain specific binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; ","K12196","VPS4; vacuolar protein-sorting-associated protein 4","hsa04144 Endocytosis - Homo sapiens (human); hsa04217 Necroptosis - Homo sapiens (human); ","IPR003593; IPR003959; IPR015415; IPR027417; IPR007330; ","\"AAA+ ATPase domain; ATPase, AAA-type, core; Vps4 oligomerisation, C-terminal; P-loop containing nucleoside triphosphate hydrolase; MIT; \"\r"]
["Q9UN70","Protocadherin gamma-C3 OS=Homo sapiens OX=9606 GN=PCDHGC3","PCDHGC3",101.08,1.8653,1,1,1,1,0.996,1.058,1.202,1.028,0.886,0.849,0.849,0.11,"plasma membrane\r","GO:0044700 single organism signaling; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0048731 system development; GO:0098609 cell-cell adhesion; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0023052 signaling; GO:0050808 synapse organization; GO:0032501 multicellular organismal process; GO:0022610 biological adhesion; GO:0007154 cell communication; GO:0007267 cell-cell signaling; GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; GO:0044767 single-organism developmental process; GO:0007155 cell adhesion; GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules; GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules; GO:0007275 multicellular organism development; GO:0048856 anatomical structure development; GO:0009987 cellular process; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0031226 intrinsic component of plasma membrane; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0044459 plasma membrane part; GO:0044464 cell part; GO:0044425 membrane part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005509 calcium ion binding; GO:0005488 binding; GO:0043167 ion binding; ","K16497",null,null,"IPR015919; IPR032455; IPR031904; IPR013164; IPR002126; ","\"Cadherin-like; Cadherin, cytoplasmic C-terminal domain; Cadherin, C-terminal catenin-binding domain; Cadherin, N-terminal; Cadherin; \"\r"]
["Q9UN86","Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2","G3BP2",54.12,22.246,15.6,6,6,6,0.999,0.974,0.997,0.99,0.875,1.113,1.003,0.979,"cytoplasm\r","GO:0044700 single organism signaling; GO:0050658 RNA transport; GO:0065008 regulation of biological quality; GO:0009968 negative regulation of signal transduction; GO:1903533 regulation of protein targeting; GO:0023051 regulation of signaling; GO:0090317 negative regulation of intracellular protein transport; GO:0044699 single-organism process; GO:0042308 negative regulation of protein import into nucleus; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:0042306 regulation of protein import into nucleus; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0050657 nucleic acid transport; GO:0015931 nucleobase-containing compound transport; GO:0032879 regulation of localization; GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling; GO:0032387 negative regulation of intracellular transport; GO:1900181 negative regulation of protein localization to nucleus; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0051651 maintenance of location in cell; GO:0046823 negative regulation of nucleocytoplasmic transport; GO:0051051 negative regulation of transport; GO:0051220 cytoplasmic sequestering of protein; GO:0051716 cellular response to stimulus; GO:0042994 cytoplasmic sequestering of transcription factor; GO:1903828 negative regulation of cellular protein localization; GO:0032507 maintenance of protein location in cell; GO:0042992 negative regulation of transcription factor import into nucleus; GO:0042345 regulation of NF-kappaB import into nucleus; GO:0044763 single-organism cellular process; GO:0032386 regulation of intracellular transport; GO:0007264 small GTPase mediated signal transduction; GO:0023052 signaling; GO:0006810 transport; GO:0050789 regulation of biological process; GO:1902532 negative regulation of intracellular signal transduction; GO:0048583 regulation of response to stimulus; GO:1900180 regulation of protein localization to nucleus; GO:0051223 regulation of protein transport; GO:0042347 negative regulation of NF-kappaB import into nucleus; GO:0007265 Ras protein signal transduction; GO:0050794 regulation of cellular process; GO:0007253 cytoplasmic sequestering of NF-kappaB; GO:0051028 mRNA transport; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:1904589 regulation of protein import; GO:0050896 response to stimulus; GO:1904590 negative regulation of protein import; GO:0051236 establishment of RNA localization; GO:0070201 regulation of establishment of protein localization; GO:0060341 regulation of cellular localization; GO:0042990 regulation of transcription factor import into nucleus; GO:0023057 negative regulation of signaling; GO:1902578 single-organism localization; GO:0010648 negative regulation of cell communication; GO:0051235 maintenance of location; GO:0032880 regulation of protein localization; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0009966 regulation of signal transduction; GO:0033157 regulation of intracellular protein transport; GO:1902531 regulation of intracellular signal transduction; GO:0045185 maintenance of protein location; GO:0035556 intracellular signal transduction; GO:0051224 negative regulation of protein transport; GO:0006403 RNA localization; GO:0051049 regulation of transport; GO:0071702 organic substance transport; GO:0048585 negative regulation of response to stimulus; GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling; GO:0051641 cellular localization; GO:0070727 cellular macromolecule localization; GO:0046822 regulation of nucleocytoplasmic transport; GO:1904950 negative regulation of establishment of protein localization; GO:0051179 localization; GO:0071705 nitrogen compound transport; GO:1903827 regulation of cellular protein localization; GO:0065007 biological regulation; ","GO:0005622 intracellular; GO:0044464 cell part; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:1990904 ribonucleoprotein complex; GO:0005829 cytosol; GO:0005623 cell; GO:0030529 intracellular ribonucleoprotein complex; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032947 protein complex scaffold; GO:0003729 mRNA binding; GO:0003723 RNA binding; GO:1901265 nucleoside phosphate binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0030159 receptor signaling complex scaffold activity; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0005198 structural molecule activity; GO:0036094 small molecule binding; ",{"$nulls":3},"IPR002075; IPR018222; IPR000504; IPR012677; IPR032710; ","\"Nuclear transport factor 2; Nuclear transport factor 2, eukaryote; RNA recognition motif domain; Nucleotide-binding alpha-beta plait domain; NTF2-like domain; \"\r"]
["Q9UNE7","E3 ubiquitin-protein ligase CHIP OS=Homo sapiens OX=9606 GN=STUB1","STUB1",34.856,18.07,18.8,6,8,6,1.002,0.938,0.988,1.049,0.978,1.017,1.04,0.245,"cytoplasm\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0007166 cell surface receptor signaling pathway; GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0051443 positive regulation of ubiquitin-protein transferase activity; GO:0036503 ERAD pathway; GO:0032091 negative regulation of protein binding; GO:0019216 regulation of lipid metabolic process; GO:1903845 negative regulation of cellular response to transforming growth factor beta stimulus; GO:0051865 protein autoubiquitination; GO:0044237 cellular metabolic process; GO:1903364 positive regulation of cellular protein catabolic process; GO:0008152 metabolic process; GO:0035966 response to topologically incorrect protein; GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0044093 positive regulation of molecular function; GO:0038127 ERBB signaling pathway; GO:0051347 positive regulation of transferase activity; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:1903362 regulation of cellular protein catabolic process; GO:0051716 cellular response to stimulus; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0090287 regulation of cellular response to growth factor stimulus; GO:0090035 positive regulation of chaperone-mediated protein complex assembly; GO:0031323 regulation of cellular metabolic process; GO:1901575 organic substance catabolic process; GO:0030163 protein catabolic process; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0061136 regulation of proteasomal protein catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0010817 regulation of hormone levels; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0034976 response to endoplasmic reticulum stress; GO:0006259 DNA metabolic process; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0019218 regulation of steroid metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0000209 protein polyubiquitination; GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0023057 negative regulation of signaling; GO:0046483 heterocycle metabolic process; GO:0010648 negative regulation of cell communication; GO:0006139 nucleobase-containing compound metabolic process; GO:0009896 positive regulation of catabolic process; GO:0051338 regulation of transferase activity; GO:0044248 cellular catabolic process; GO:0042176 regulation of protein catabolic process; GO:0009966 regulation of signal transduction; GO:0006986 response to unfolded protein; GO:0006950 response to stress; GO:0016567 protein ubiquitination; GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0010033 response to organic substance; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0006974 cellular response to DNA damage stimulus; GO:0051247 positive regulation of protein metabolic process; GO:0031943 regulation of glucocorticoid metabolic process; GO:0032446 protein modification by small protein conjugation; GO:0051438 regulation of ubiquitin-protein transferase activity; GO:0031398 positive regulation of protein ubiquitination; GO:0031325 positive regulation of cellular metabolic process; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0031647 regulation of protein stability; GO:0043412 macromolecule modification; GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process; GO:0009968 negative regulation of signal transduction; GO:0031331 positive regulation of cellular catabolic process; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0030968 endoplasmic reticulum unfolded protein response; GO:0031396 regulation of protein ubiquitination; GO:0051130 positive regulation of cellular component organization; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0090034 regulation of chaperone-mediated protein complex assembly; GO:0031334 positive regulation of protein complex assembly; GO:0006515 misfolded or incompletely synthesized protein catabolic process; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0070887 cellular response to chemical stimulus; GO:0051098 regulation of binding; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0023052 signaling; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0043254 regulation of protein complex assembly; GO:0090304 nucleic acid metabolic process; GO:0051100 negative regulation of binding; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0036211 protein modification process; GO:0070534 protein K63-linked ubiquitination; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0035967 cellular response to topologically incorrect protein; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0017015 regulation of transforming growth factor beta receptor signaling pathway; GO:0044087 regulation of cellular component biogenesis; GO:0050896 response to stimulus; GO:0071218 cellular response to misfolded protein; GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0010498 proteasomal protein catabolic process; GO:0071704 organic substance metabolic process; GO:0043393 regulation of protein binding; GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; GO:1903322 positive regulation of protein modification by small protein conjugation or removal; GO:0045862 positive regulation of proteolysis; GO:0090288 negative regulation of cellular response to growth factor stimulus; GO:0034641 cellular nitrogen compound metabolic process; GO:0006508 proteolysis; GO:0009987 cellular process; GO:0043632 modification-dependent macromolecule catabolic process; GO:0032350 regulation of hormone metabolic process; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0034620 cellular response to unfolded protein; GO:0051788 response to misfolded protein; GO:0019941 modification-dependent protein catabolic process; GO:0044712 single-organism catabolic process; GO:1901800 positive regulation of proteasomal protein catabolic process; GO:0006807 nitrogen compound metabolic process; GO:0031401 positive regulation of protein modification process; GO:0048585 negative regulation of response to stimulus; GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:1903844 regulation of cellular response to transforming growth factor beta stimulus; GO:0006281 DNA repair; GO:0038128 ERBB2 signaling pathway; GO:0051246 regulation of protein metabolic process; GO:0009057 macromolecule catabolic process; GO:0030579 ubiquitin-dependent SMAD protein catabolic process; GO:0010467 gene expression; GO:0045732 positive regulation of protein catabolic process; GO:0051128 regulation of cellular component organization; GO:0051604 protein maturation; GO:0009056 catabolic process; GO:0044089 positive regulation of cellular component biogenesis; GO:0065007 biological regulation; ","GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0030016 myofibril; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0030018 Z disc; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0031674 I band; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043292 contractile fiber; GO:0031371 ubiquitin conjugating enzyme complex; GO:0000151 ubiquitin ligase complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0042405 nuclear inclusion body; GO:0016234 inclusion body; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:1990234 transferase complex; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0099081 supramolecular polymer; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0030017 sarcomere; GO:0044449 contractile fiber part; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0030674 protein binding, bridging; GO:0031072 heat shock protein binding; GO:0019787 ubiquitin-like protein transferase activity; GO:0031625 ubiquitin protein ligase binding; GO:0005102 receptor binding; GO:0046983 protein dimerization activity; GO:0034450 ubiquitin-ubiquitin ligase activity; GO:0051787 misfolded protein binding; GO:0051879 Hsp90 protein binding; GO:0005515 protein binding; GO:0061659 ubiquitin-like protein ligase activity; GO:0019900 kinase binding; GO:0030544 Hsp70 protein binding; GO:0061630 ubiquitin protein ligase activity; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway; GO:0004842 ubiquitin-protein transferase activity; GO:0030911 TPR domain binding; GO:0060090 binding, bridging; GO:0001664 G-protein coupled receptor binding; GO:0019904 protein domain specific binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0046332 SMAD binding; GO:0016740 transferase activity; GO:0019899 enzyme binding; ","K09561","STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]","hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human); hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); ","IPR003613; IPR011990; IPR013083; IPR013026; ","\"U box domain; Tetratricopeptide-like helical domain; Zinc finger, RING/FYVE/PHD-type; Tetratricopeptide repeat-containing domain; \"\r"]
["Q9UNF0","Protein kinase C and casein kinase substrate in neurons protein 2 OS=Homo sapiens OX=9606 GN=PACSIN2","PACSIN2",55.738,23.862,14,8,9,8,0.993,0.955,1.021,1.009,0.951,1.028,1.006,0.848,"nucleus\r","GO:0050794 regulation of cellular process; GO:0060627 regulation of vesicle-mediated transport; GO:0044085 cellular component biogenesis; GO:0016043 cellular component organization; GO:0010256 endomembrane system organization; GO:0048869 cellular developmental process; GO:0051129 negative regulation of cellular component organization; GO:0070836 caveola assembly; GO:0032989 cellular component morphogenesis; GO:0044699 single-organism process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0051234 establishment of localization; GO:0009653 anatomical structure morphogenesis; GO:0036010 protein localization to endosome; GO:0030036 actin cytoskeleton organization; GO:0045806 negative regulation of endocytosis; GO:0032990 cell part morphogenesis; GO:0022607 cellular component assembly; GO:0032879 regulation of localization; GO:0044854 plasma membrane raft assembly; GO:0048858 cell projection morphogenesis; GO:0033365 protein localization to organelle; GO:0007010 cytoskeleton organization; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0034613 cellular protein localization; GO:0031579 membrane raft organization; GO:0009987 cellular process; GO:0032502 developmental process; GO:0051051 negative regulation of transport; GO:0030100 regulation of endocytosis; GO:0051049 regulation of transport; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0071709 membrane assembly; GO:0044802 single-organism membrane organization; GO:0007009 plasma membrane organization; GO:0006897 endocytosis; GO:0001765 membrane raft assembly; GO:0044857 plasma membrane raft organization; GO:0044091 membrane biogenesis; GO:0051641 cellular localization; GO:0006810 transport; GO:0000902 cell morphogenesis; GO:1902589 single-organism organelle organization; GO:0070727 cellular macromolecule localization; GO:0050789 regulation of biological process; GO:0030030 cell projection organization; GO:0072584 caveolin-mediated endocytosis; GO:0044767 single-organism developmental process; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0061024 membrane organization; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0048856 anatomical structure development; GO:0097320 plasma membrane tubulation; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0019898 extrinsic component of membrane; GO:0098857 membrane microdomain; GO:0032587 ruffle membrane; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0005925 focal adhesion; GO:0098590 plasma membrane region; GO:0031256 leading edge membrane; GO:0016607 nuclear speck; GO:0005622 intracellular; GO:0098589 membrane region; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0005924 cell-substrate adherens junction; GO:0031252 cell leading edge; GO:0010008 endosome membrane; GO:0042995 cell projection; GO:0070161 anchoring junction; GO:0012506 vesicle membrane; GO:0031981 nuclear lumen; GO:0044440 endosomal part; GO:0005901 caveola; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0055038 recycling endosome membrane; GO:0005911 cell-cell junction; GO:0016604 nuclear body; GO:0055037 recycling endosome; GO:0005856 cytoskeleton; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0044464 cell part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0005912 adherens junction; GO:0005768 endosome; GO:0045121 membrane raft; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0005634 nucleus; GO:0044459 plasma membrane part; GO:0044853 plasma membrane raft; GO:0001726 ruffle; GO:0031253 cell projection membrane; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0050839 cell adhesion molecule binding; GO:0008092 cytoskeletal protein binding; GO:0042802 identical protein binding; GO:0070300 phosphatidic acid binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0005543 phospholipid binding; GO:0043167 ion binding; GO:0008289 lipid binding; GO:0005515 protein binding; GO:0043168 anion binding; GO:0005215 transporter activity; ","K20123",null,null,"IPR001452; IPR031160; IPR001060; ","SH3 domain; F-BAR domain; FCH domain; \r"]
["Q9UNF1","Melanoma-associated antigen D2 OS=Homo sapiens OX=9606 GN=MAGED2","MAGED2",64.953,17.216,8.4,4,4,4,0.816,1.853,0.7,1.064,0.759,0.861,0.797,0.682,"nucleus\r","GO:0000003 reproduction; GO:0070293 renal absorption; GO:0022414 reproductive process; GO:0030001 metal ion transport; GO:0002576 platelet degranulation; GO:0044699 single-organism process; GO:0051234 establishment of localization; GO:0007565 female pregnancy; GO:1902578 single-organism localization; GO:0006812 cation transport; GO:0003096 renal sodium ion transport; GO:0044706 multi-multicellular organism process; GO:0070294 renal sodium ion absorption; GO:0009987 cellular process; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0003008 system process; GO:0003014 renal system process; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0006814 sodium ion transport; GO:0006810 transport; GO:0045055 regulated exocytosis; GO:0006811 ion transport; GO:0032940 secretion by cell; GO:0044703 multi-organism reproductive process; GO:0051179 localization; GO:0015672 monovalent inorganic cation transport; GO:0006887 exocytosis; ","GO:0034774 secretory granule lumen; GO:0016020 membrane; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0031093 platelet alpha granule lumen; GO:0031091 platelet alpha granule; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR002190; ","MAGE homology domain; \r"]
["Q9UNH7","Sorting nexin-6 OS=Homo sapiens OX=9606 GN=SNX6","SNX6",46.648,77.398,28.6,13,21,13,1.04,1.025,0.976,0.986,1.028,1.004,0.992,0.762,"cytoplasm\r","GO:0009968 negative regulation of signal transduction; GO:1901185 negative regulation of ERBB signaling pathway; GO:0023051 regulation of signaling; GO:1903845 negative regulation of cellular response to transforming growth factor beta stimulus; GO:0051253 negative regulation of RNA metabolic process; GO:0010469 regulation of receptor activity; GO:0031400 negative regulation of protein modification process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:2001141 regulation of RNA biosynthetic process; GO:0051649 establishment of localization in cell; GO:0010646 regulation of cell communication; GO:0033673 negative regulation of kinase activity; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0010468 regulation of gene expression; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0061097 regulation of protein tyrosine kinase activity; GO:0090287 regulation of cellular response to growth factor stimulus; GO:0051348 negative regulation of transferase activity; GO:0031323 regulation of cellular metabolic process; GO:0043086 negative regulation of catalytic activity; GO:0010506 regulation of autophagy; GO:0010605 negative regulation of macromolecule metabolic process; GO:0016197 endosomal transport; GO:0016241 regulation of macroautophagy; GO:0006810 transport; GO:1903506 regulation of nucleic acid-templated transcription; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0042147 retrograde transport, endosome to Golgi; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:1902679 negative regulation of RNA biosynthetic process; GO:0048583 regulation of response to stimulus; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0006469 negative regulation of protein kinase activity; GO:0044092 negative regulation of molecular function; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0043549 regulation of kinase activity; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0045859 regulation of protein kinase activity; GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0050730 regulation of peptidyl-tyrosine phosphorylation; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0017015 regulation of transforming growth factor beta receptor signaling pathway; GO:0031399 regulation of protein modification process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0045892 negative regulation of transcription, DNA-templated; GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway; GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:1901184 regulation of ERBB signaling pathway; GO:0009889 regulation of biosynthetic process; GO:0042326 negative regulation of phosphorylation; GO:0090288 negative regulation of cellular response to growth factor stimulus; GO:0061099 negative regulation of protein tyrosine kinase activity; GO:0006886 intracellular protein transport; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0001933 negative regulation of protein phosphorylation; GO:0034613 cellular protein localization; GO:0016482 cytosolic transport; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0009987 cellular process; GO:0009966 regulation of signal transduction; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0016192 vesicle-mediated transport; GO:0001932 regulation of protein phosphorylation; GO:0016050 vesicle organization; GO:0010556 regulation of macromolecule biosynthetic process; GO:0071702 organic substance transport; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway; GO:0048585 negative regulation of response to stimulus; GO:2000272 negative regulation of receptor activity; GO:0006897 endocytosis; GO:0051252 regulation of RNA metabolic process; GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation; GO:0009892 negative regulation of metabolic process; GO:0007175 negative regulation of epidermal growth factor-activated receptor activity; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:1903844 regulation of cellular response to transforming growth factor beta stimulus; GO:0070727 cellular macromolecule localization; GO:0009890 negative regulation of biosynthetic process; GO:0051246 regulation of protein metabolic process; GO:0006996 organelle organization; GO:0010563 negative regulation of phosphorus metabolic process; GO:0007176 regulation of epidermal growth factor-activated receptor activity; GO:0051248 negative regulation of protein metabolic process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0042058 regulation of epidermal growth factor receptor signaling pathway; GO:0051179 localization; GO:0045936 negative regulation of phosphate metabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0030904 retromer complex; GO:0031090 organelle membrane; GO:0019898 extrinsic component of membrane; GO:0031410 cytoplasmic vesicle; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005768 endosome; GO:0031901 early endosome membrane; GO:0043227 membrane-bounded organelle; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0010008 endosome membrane; GO:0097422 tubular endosome; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0005829 cytosol; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0030905 retromer, tubulation complex; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0034452 dynactin binding; GO:0042802 identical protein binding; GO:0008092 cytoskeletal protein binding; GO:0046982 protein heterodimerization activity; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0035091 phosphatidylinositol binding; GO:0005543 phospholipid binding; GO:0043167 ion binding; GO:0046983 protein dimerization activity; GO:0008289 lipid binding; GO:0043168 anion binding; GO:0005515 protein binding; ","K17920","SNX5_6_32; sorting nexin-5/6/32","hsa04144 Endocytosis - Homo sapiens (human); ","IPR015404; IPR027267; IPR001683; ","\"Sorting nexin Vps5-like, C-terminal; Arfaptin homology (AH) domain/BAR domain; Phox homologous domain; \"\r"]
["Q9UNK0","Syntaxin-8 OS=Homo sapiens OX=9606 GN=STX8","STX8",26.906,31.757,16.1,3,3,3,0.998,0.984,1.008,0.949,1.009,1.043,1.004,0.922,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0090174 organelle membrane fusion; GO:0046907 intracellular transport; GO:1903076 regulation of protein localization to plasma membrane; GO:0044699 single-organism process; GO:0022406 membrane docking; GO:0015031 protein transport; GO:0060341 regulation of cellular localization; GO:0051234 establishment of localization; GO:0098927 vesicle-mediated transport between endosomal compartments; GO:1903729 regulation of plasma membrane organization; GO:1905475 regulation of protein localization to membrane; GO:1904375 regulation of protein localization to cell periphery; GO:0051649 establishment of localization in cell; GO:0032879 regulation of localization; GO:0006886 intracellular protein transport; GO:0032880 regulation of protein localization; GO:0044801 single-organism membrane fusion; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0034613 cellular protein localization; GO:0016482 cytosolic transport; GO:0009987 cellular process; GO:0045022 early endosome to late endosome transport; GO:0007041 lysosomal transport; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0044802 single-organism membrane organization; GO:0016050 vesicle organization; GO:0061025 membrane fusion; GO:0048284 organelle fusion; GO:0071702 organic substance transport; GO:0048278 vesicle docking; GO:0008333 endosome to lysosome transport; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:0016197 endosomal transport; GO:1902589 single-organism organelle organization; GO:0070727 cellular macromolecule localization; GO:0050789 regulation of biological process; GO:0006996 organelle organization; GO:0007034 vacuolar transport; GO:0061024 membrane organization; GO:0006906 vesicle fusion; GO:0065009 regulation of molecular function; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:1903827 regulation of cellular protein localization; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0098796 membrane protein complex; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0055037 recycling endosome; GO:0005765 lysosomal membrane; GO:0031902 late endosome membrane; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005764 lysosome; GO:0098791 Golgi subcompartment; GO:0048471 perinuclear region of cytoplasm; GO:0044431 Golgi apparatus part; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0031201 SNARE complex; GO:0000323 lytic vacuole; GO:0010008 endosome membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0031226 intrinsic component of plasma membrane; GO:0005770 late endosome; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0044440 endosomal part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044459 plasma membrane part; GO:0044437 vacuolar part; GO:0005802 trans-Golgi network; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0043234 protein complex; GO:0005794 Golgi apparatus; GO:0031984 organelle subcompartment; GO:0044444 cytoplasmic part; ","GO:0000149 SNARE binding; GO:0005484 SNAP receptor activity; GO:0008200 ion channel inhibitor activity; GO:0031625 ubiquitin protein ligase binding; GO:0016247 channel regulator activity; GO:0005488 binding; GO:0099106 ion channel regulator activity; GO:0005515 protein binding; GO:0019869 chloride channel inhibitor activity; GO:0098772 molecular function regulator; GO:0044389 ubiquitin-like protein ligase binding; GO:0019905 syntaxin binding; GO:0016248 channel inhibitor activity; GO:0019899 enzyme binding; GO:0017081 chloride channel regulator activity; ","K08501","STX8; syntaxin 8","hsa04130 SNARE interactions in vesicular transport - Homo sapiens (human); ","IPR000727; ","Target SNARE coiled-coil homology domain; \r"]
["Q9UNL2","Translocon-associated protein subunit gamma OS=Homo sapiens OX=9606 GN=SSR3","SSR3",21.08,34.108,11.9,2,3,2,0.978,1.021,0.965,1.067,0.984,0.996,1.028,0.421,"plasma membrane\r","GO:0046907 intracellular transport; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0072594 establishment of protein localization to organelle; GO:0072657 protein localization to membrane; GO:0045047 protein targeting to ER; GO:0071702 organic substance transport; GO:0006613 cotranslational protein targeting to membrane; GO:0015031 protein transport; GO:0051641 cellular localization; GO:0051234 establishment of localization; GO:0045184 establishment of protein localization; GO:0006605 protein targeting; GO:0006810 transport; GO:0006612 protein targeting to membrane; GO:0070727 cellular macromolecule localization; GO:0051649 establishment of localization in cell; GO:0070972 protein localization to endoplasmic reticulum; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0006886 intracellular protein transport; GO:0033365 protein localization to organelle; GO:0051179 localization; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0034613 cellular protein localization; GO:0090150 establishment of protein localization to membrane; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044432 endoplasmic reticulum part; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; ",null,"K13251","SSR3; translocon-associated protein subunit gamma","hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); "]
["Q9UNM6","26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13","PSMD13",42.945,55.219,38.8,15,24,15,0.925,0.938,0.945,1.07,1.095,1.036,1.14,0.00162,"cytoplasm\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0022414 reproductive process; GO:0010608 posttranscriptional regulation of gene expression; GO:0051443 positive regulation of ubiquitin-protein transferase activity; GO:0031347 regulation of defense response; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:1903364 positive regulation of cellular protein catabolic process; GO:0008152 metabolic process; GO:0065003 macromolecular complex assembly; GO:0044093 positive regulation of molecular function; GO:0090263 positive regulation of canonical Wnt signaling pathway; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0016055 Wnt signaling pathway; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0006521 regulation of cellular amino acid metabolic process; GO:0080090 regulation of primary metabolic process; GO:0010972 negative regulation of G2/M transition of mitotic cell cycle; GO:0044763 single-organism cellular process; GO:0060828 regulation of canonical Wnt signaling pathway; GO:0043086 negative regulation of catalytic activity; GO:0033209 tumor necrosis factor-mediated signaling pathway; GO:0050776 regulation of immune response; GO:0006810 transport; GO:0000165 MAPK cascade; GO:1901575 organic substance catabolic process; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0007267 cell-cell signaling; GO:0002223 stimulatory C-type lectin receptor signaling pathway; GO:0030163 protein catabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0060071 Wnt signaling pathway, planar cell polarity pathway; GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0000003 reproduction; GO:0016310 phosphorylation; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0048519 negative regulation of biological process; GO:1903047 mitotic cell cycle process; GO:0043487 regulation of RNA stability; GO:0000209 protein polyubiquitination; GO:0023057 negative regulation of signaling; GO:0010648 negative regulation of cell communication; GO:0009889 regulation of biosynthetic process; GO:0009896 positive regulation of catabolic process; GO:0043620 regulation of DNA-templated transcription in response to stress; GO:0070482 response to oxygen levels; GO:0044248 cellular catabolic process; GO:0042176 regulation of protein catabolic process; GO:0038093 Fc receptor signaling pathway; GO:0050778 positive regulation of immune response; GO:0023014 signal transduction by protein phosphorylation; GO:0006950 response to stress; GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; GO:0016567 protein ubiquitination; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0002263 cell activation involved in immune response; GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress; GO:1903321 negative regulation of protein modification by small protein conjugation or removal; GO:0045055 regulated exocytosis; GO:0031398 positive regulation of protein ubiquitination; GO:0032446 protein modification by small protein conjugation; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0030177 positive regulation of Wnt signaling pathway; GO:1904668 positive regulation of ubiquitin protein ligase activity; GO:0000280 nuclear division; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0006955 immune response; GO:0043412 macromolecule modification; GO:0070646 protein modification by small protein removal; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0031331 positive regulation of cellular catabolic process; GO:0044699 single-organism process; GO:0031400 negative regulation of protein modification process; GO:0006796 phosphate-containing compound metabolic process; GO:0031396 regulation of protein ubiquitination; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0045930 negative regulation of mitotic cell cycle; GO:0009893 positive regulation of metabolic process; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0034612 response to tumor necrosis factor; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0051726 regulation of cell cycle; GO:0034097 response to cytokine; GO:0031326 regulation of cellular biosynthetic process; GO:0051321 meiotic cell cycle; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0198738 cell-cell signaling by wnt; GO:0010565 regulation of cellular ketone metabolic process; GO:0032940 secretion by cell; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0070271 protein complex biogenesis; GO:0036211 protein modification process; GO:0090175 regulation of establishment of planar polarity; GO:0016043 cellular component organization; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0045786 negative regulation of cell cycle; GO:0044257 cellular protein catabolic process; GO:1901988 negative regulation of cell cycle phase transition; GO:1903320 regulation of protein modification by small protein conjugation or removal; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0048285 organelle fission; GO:0010498 proteasomal protein catabolic process; GO:0071704 organic substance metabolic process; GO:0045862 positive regulation of proteolysis; GO:2000027 regulation of organ morphogenesis; GO:0006468 protein phosphorylation; GO:0023056 positive regulation of signaling; GO:0001666 response to hypoxia; GO:0002757 immune response-activating signal transduction; GO:0010647 positive regulation of cell communication; GO:0071453 cellular response to oxygen levels; GO:0019221 cytokine-mediated signaling pathway; GO:0043623 cellular protein complex assembly; GO:0031397 negative regulation of protein ubiquitination; GO:0034622 cellular macromolecular complex assembly; GO:0006355 regulation of transcription, DNA-templated; GO:0035556 intracellular signal transduction; GO:0019941 modification-dependent protein catabolic process; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia; GO:1902749 regulation of cell cycle G2/M phase transition; GO:0043488 regulation of mRNA stability; GO:0043085 positive regulation of catalytic activity; GO:0043933 macromolecular complex subunit organization; GO:0002366 leukocyte activation involved in immune response; GO:0019882 antigen processing and presentation; GO:0042119 neutrophil activation; GO:0050852 T cell receptor signaling pathway; GO:0002684 positive regulation of immune system process; GO:0038095 Fc-epsilon receptor signaling pathway; GO:0051248 negative regulation of protein metabolic process; GO:0022402 cell cycle process; GO:1902750 negative regulation of cell cycle G2/M phase transition; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0045321 leukocyte activation; GO:0002220 innate immune response activating cell surface receptor signaling pathway; GO:0007166 cell surface receptor signaling pathway; GO:0071345 cellular response to cytokine stimulus; GO:0044702 single organism reproductive process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0051347 positive regulation of transferase activity; GO:1903362 regulation of cellular protein catabolic process; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0002443 leukocyte mediated immunity; GO:0002758 innate immune response-activating signal transduction; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0031323 regulation of cellular metabolic process; GO:2000058 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0010948 negative regulation of cell cycle process; GO:0032269 negative regulation of cellular protein metabolic process; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0002682 regulation of immune system process; GO:0031145 anaphase-promoting complex-dependent catabolic process; GO:0050794 regulation of cellular process; GO:0043248 proteasome assembly; GO:0033554 cellular response to stress; GO:0007346 regulation of mitotic cell cycle; GO:0002283 neutrophil activation involved in immune response; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:0051239 regulation of multicellular organismal process; GO:0031349 positive regulation of defense response; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:1901987 regulation of cell cycle phase transition; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0010389 regulation of G2/M transition of mitotic cell cycle; GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; GO:0009966 regulation of signal transduction; GO:0006461 protein complex assembly; GO:0038061 NIK/NF-kappaB signaling; GO:0071456 cellular response to hypoxia; GO:0002253 activation of immune response; GO:0016192 vesicle-mediated transport; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1904666 regulation of ubiquitin protein ligase activity; GO:0055085 transmembrane transport; GO:0051247 positive regulation of protein metabolic process; GO:0051438 regulation of ubiquitin-protein transferase activity; GO:0030111 regulation of Wnt signaling pathway; GO:0006793 phosphorus metabolic process; GO:0001775 cell activation; GO:0036293 response to decreased oxygen levels; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process; GO:0006887 exocytosis; GO:0051444 negative regulation of ubiquitin-protein transferase activity; GO:0090090 negative regulation of canonical Wnt signaling pathway; GO:0051234 establishment of localization; GO:0035567 non-canonical Wnt signaling pathway; GO:1905330 regulation of morphogenesis of an epithelium; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:1901991 negative regulation of mitotic cell cycle phase transition; GO:0022607 cellular component assembly; GO:0045088 regulation of innate immune response; GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I; GO:0070887 cellular response to chemical stimulus; GO:0002274 myeloid leukocyte activation; GO:0050851 antigen receptor-mediated signaling pathway; GO:0010468 regulation of gene expression; GO:0071822 protein complex subunit organization; GO:0030178 negative regulation of Wnt signaling pathway; GO:0048002 antigen processing and presentation of peptide antigen; GO:0002446 neutrophil mediated immunity; GO:0048522 positive regulation of cellular process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0051348 negative regulation of transferase activity; GO:0070647 protein modification by small protein conjugation or removal; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0042221 response to chemical; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0019222 regulation of metabolic process; GO:0043299 leukocyte degranulation; GO:2000026 regulation of multicellular organismal development; GO:1904667 negative regulation of ubiquitin protein ligase activity; GO:1903046 meiotic cell cycle process; GO:0002218 activation of innate immune response; GO:0002252 immune effector process; GO:0071356 cellular response to tumor necrosis factor; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0016579 protein deubiquitination; GO:0007127 meiosis I; GO:1903322 positive regulation of protein modification by small protein conjugation or removal; GO:0006508 proteolysis; GO:0036230 granulocyte activation; GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:0009987 cellular process; GO:0033238 regulation of cellular amine metabolic process; GO:0043632 modification-dependent macromolecule catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0045089 positive regulation of innate immune response; GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition; GO:0031401 positive regulation of protein modification process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048585 negative regulation of response to stimulus; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0051246 regulation of protein metabolic process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0009057 macromolecule catabolic process; GO:0007126 meiotic nuclear division; GO:0009967 positive regulation of signal transduction; GO:0045732 positive regulation of protein catabolic process; GO:0036294 cellular response to decreased oxygen levels; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0034774 secretory granule lumen; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005838 proteasome regulatory particle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:1905369 endopeptidase complex; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:1902494 catalytic complex; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0022624 proteasome accessory complex; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:1905368 peptidase complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0008541 proteasome regulatory particle, lid subcomplex; GO:0000502 proteasome complex; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0005198 structural molecule activity; GO:0005488 binding; ","K03039","PSMD13; 26S proteasome regulatory subunit N9","hsa03050 Proteasome - Homo sapiens (human); hsa05169 Epstein-Barr virus infection - Homo sapiens (human); ","IPR011991; IPR000717; ","Winged helix-turn-helix DNA-binding domain; Proteasome component (PCI) domain; \r"]
["Q9UNP9","Peptidyl-prolyl cis-trans isomerase E OS=Homo sapiens OX=9606 GN=PPIE","PPIE",33.43,4.7014,9,3,3,2,0.938,1.028,1.036,1.054,0.979,0.974,1.002,0.963,"nucleus\r","GO:0045321 leukocyte activation; GO:0006289 nucleotide-excision repair; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:0006457 protein folding; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0006396 RNA processing; GO:1903902 positive regulation of viral life cycle; GO:0010468 regulation of gene expression; GO:0051716 cellular response to stimulus; GO:0043902 positive regulation of multi-organism process; GO:0002443 leukocyte mediated immunity; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0045069 regulation of viral genome replication; GO:0031323 regulation of cellular metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:0006810 transport; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0032940 secretion by cell; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006464 cellular protein modification process; GO:0043299 leukocyte degranulation; GO:0036211 protein modification process; GO:0016071 mRNA metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0002283 neutrophil activation involved in immune response; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0006725 cellular aromatic compound metabolic process; GO:0006283 transcription-coupled nucleotide-excision repair; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0006259 DNA metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0036230 granulocyte activation; GO:0045070 positive regulation of viral genome replication; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0006355 regulation of transcription, DNA-templated; GO:0006950 response to stress; GO:0043900 regulation of multi-organism process; GO:0016192 vesicle-mediated transport; GO:0050792 regulation of viral process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0002376 immune system process; GO:0000413 protein peptidyl-prolyl isomerization; GO:0018208 peptidyl-proline modification; GO:0044238 primary metabolic process; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0002263 cell activation involved in immune response; GO:0006974 cellular response to DNA damage stimulus; GO:0018193 peptidyl-amino acid modification; GO:0002366 leukocyte activation involved in immune response; GO:0045055 regulated exocytosis; GO:0006281 DNA repair; GO:0042119 neutrophil activation; GO:0048524 positive regulation of viral process; GO:0001775 cell activation; GO:0010467 gene expression; GO:1903900 regulation of viral life cycle; GO:0043412 macromolecule modification; GO:0051179 localization; GO:0006955 immune response; GO:0006887 exocytosis; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0005681 spliceosomal complex; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0071013 catalytic step 2 spliceosome; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0003723 RNA binding; GO:0003755 peptidyl-prolyl cis-trans isomerase activity; GO:1901265 nucleoside phosphate binding; GO:0005515 protein binding; GO:0008144 drug binding; GO:0033218 amide binding; GO:0000166 nucleotide binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016853 isomerase activity; GO:0042277 peptide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0016018 cyclosporin A binding; GO:0016859 cis-trans isomerase activity; GO:0036094 small molecule binding; ","K09564","PPIE; peptidyl-prolyl isomerase E (cyclophilin E) [EC:5.2.1.8]","hsa03040 Spliceosome - Homo sapiens (human); ","IPR002130; IPR000504; IPR034168; IPR029000; IPR012677; ","\"Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain; RNA recognition motif domain; Peptidyl-prolyl cis-trans isomerase E, RNA recognition motif; Cyclophilin-like domain; Nucleotide-binding alpha-beta plait domain; \"\r"]
["Q9UNS2","COP9 signalosome complex subunit 3 OS=Homo sapiens OX=9606 GN=COPS3","COPS3",47.873,63.694,18.2,6,7,6,1.06,0.962,0.932,1.049,0.955,1.035,1.029,0.582,"cytoplasm\r","GO:0044700 single organism signaling; GO:0070646 protein modification by small protein removal; GO:0043009 chordate embryonic development; GO:0006289 nucleotide-excision repair; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0007154 cell communication; GO:0009314 response to radiation; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0009790 embryo development; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:1901360 organic cyclic compound metabolic process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:1901575 organic substance catabolic process; GO:0000715 nucleotide-excision repair, DNA damage recognition; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0001701 in utero embryonic development; GO:0030163 protein catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0050794 regulation of cellular process; GO:0000338 protein deneddylation; GO:0033554 cellular response to stress; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0006283 transcription-coupled nucleotide-excision repair; GO:0006259 DNA metabolic process; GO:0009628 response to abiotic stimulus; GO:0044267 cellular protein metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0044248 cellular catabolic process; GO:0006508 proteolysis; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0043632 modification-dependent macromolecule catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0006950 response to stress; GO:0009416 response to light stimulus; GO:0019941 modification-dependent protein catabolic process; GO:0009792 embryo development ending in birth or egg hatching; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:0006974 cellular response to DNA damage stimulus; GO:0006281 DNA repair; GO:0051276 chromosome organization; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0009057 macromolecule catabolic process; GO:0043412 macromolecule modification; GO:0009056 catabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0008180 COP9 signalosome; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0005488 binding; ","K12177",null,null,"IPR000717; IPR011991; ","Proteasome component (PCI) domain; Winged helix-turn-helix DNA-binding domain; \r"]
["Q9UNW1","Multiple inositol polyphosphate phosphatase 1 OS=Homo sapiens OX=9606 GN=MINPP1","MINPP1",55.051,10.969,3.1,1,2,1,0.889,0.986,0.802,1.139,1.226,0.959,1.242,0.0845,"mitochondria\r","GO:0044707 single-multicellular organism process; GO:1901615 organic hydroxy compound metabolic process; GO:0006066 alcohol metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0031214 biomineral tissue development; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0032502 developmental process; GO:0009888 tissue development; GO:0001503 ossification; GO:0048731 system development; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006797 polyphosphate metabolic process; GO:0032501 multicellular organismal process; GO:0016311 dephosphorylation; GO:0019751 polyol metabolic process; GO:0030282 bone mineralization; GO:0048513 animal organ development; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0044767 single-organism developmental process; GO:0019637 organophosphate metabolic process; GO:0043647 inositol phosphate metabolic process; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:0043436 oxoacid metabolic process; ","GO:0005788 endoplasmic reticulum lumen; GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044432 endoplasmic reticulum part; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0003993 acid phosphatase activity; GO:0030351 inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity; GO:0016791 phosphatase activity; GO:0034416 bisphosphoglycerate phosphatase activity; GO:0016787 hydrolase activity; GO:0052743 inositol tetrakisphosphate phosphatase activity; GO:0052745 inositol phosphate phosphatase activity; GO:0051717 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity; GO:0052827 inositol pentakisphosphate phosphatase activity; GO:0042578 phosphoric ester hydrolase activity; GO:0003824 catalytic activity; GO:0016788 hydrolase activity, acting on ester bonds; GO:0004446 inositol-hexakisphosphate phosphatase activity; GO:0052826 inositol hexakisphosphate 2-phosphatase activity; GO:0034417 bisphosphoglycerate 3-phosphatase activity; GO:0008969 phosphohistidine phosphatase activity; ","K03103","MINPP1; multiple inositol-polyphosphate phosphatase / 2,3-bisphosphoglycerate 3-phosphatase [EC:3.1.3.62 3.1.3.80]","hsa00562 Inositol phosphate metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human); "]
["Q9UNZ2","NSFL1 cofactor p47 OS=Homo sapiens OX=9606 GN=NSFL1C","NSFL1C",40.572,85.199,40.5,13,20,13,0.974,0.962,0.937,1.043,1.009,1.053,1.081,0.0108,"nucleus\r","GO:0006997 nucleus organization; GO:0016043 cellular component organization; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0010256 endomembrane system organization; GO:0044257 cellular protein catabolic process; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0010498 proteasomal protein catabolic process; GO:0006998 nuclear envelope organization; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0044248 cellular catabolic process; GO:0006508 proteolysis; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0009987 cellular process; GO:0031468 nuclear envelope reassembly; GO:0043632 modification-dependent macromolecule catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0019941 modification-dependent protein catabolic process; GO:0044763 single-organism cellular process; GO:0044802 single-organism membrane organization; GO:0061025 membrane fusion; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0044238 primary metabolic process; GO:1901575 organic substance catabolic process; GO:0007030 Golgi organization; GO:0006996 organelle organization; GO:0030163 protein catabolic process; GO:0061024 membrane organization; GO:0009057 macromolecule catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0005694 chromosome; GO:0098791 Golgi subcompartment; GO:0044431 Golgi apparatus part; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0005795 Golgi stack; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:1990730 VCP-NSFL1C complex; GO:0005634 nucleus; GO:0045111 intermediate filament cytoskeleton; GO:0005794 Golgi apparatus; GO:0043234 protein complex; GO:0031984 organelle subcompartment; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0051117 ATPase binding; GO:0005488 binding; GO:0005543 phospholipid binding; GO:0043167 ion binding; GO:0008289 lipid binding; GO:0043130 ubiquitin binding; GO:0005515 protein binding; GO:0043168 anion binding; GO:0032182 ubiquitin-like protein binding; GO:0019899 enzyme binding; ","K14012","SHP1; UBX domain-containing protein 1","hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); ","IPR029071; IPR001012; IPR012989; IPR009060; ","Ubiquitin-related domain; UBX domain; SEP domain; UBA-like; \r"]
["Q9UPN3","Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 OS=Homo sapiens OX=9606 GN=MACF1","MACF1",838.3,202.87,7.1,43,50,41,0.916,0.914,0.902,1.083,1.114,1.081,1.2,7.7e-05,"cytoplasm\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0007166 cell surface receptor signaling pathway; GO:0090002 establishment of protein localization to plasma membrane; GO:0015031 protein transport; GO:0045927 positive regulation of growth; GO:0001558 regulation of cell growth; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0032535 regulation of cellular component size; GO:0016055 Wnt signaling pathway; GO:0008104 protein localization; GO:0044765 single-organism transport; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0072657 protein localization to membrane; GO:0010632 regulation of epithelial cell migration; GO:0030307 positive regulation of cell growth; GO:0048699 generation of neurons; GO:0031346 positive regulation of cell projection organization; GO:0044763 single-organism cellular process; GO:0045773 positive regulation of axon extension; GO:0007009 plasma membrane organization; GO:1901888 regulation of cell junction assembly; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:0032886 regulation of microtubule-based process; GO:0007267 cell-cell signaling; GO:0048583 regulation of response to stimulus; GO:0051094 positive regulation of developmental process; GO:0010975 regulation of neuron projection development; GO:0050794 regulation of cellular process; GO:0001952 regulation of cell-matrix adhesion; GO:0044707 single-multicellular organism process; GO:1990778 protein localization to cell periphery; GO:0051239 regulation of multicellular organismal process; GO:0045597 positive regulation of cell differentiation; GO:1902578 single-organism localization; GO:0050772 positive regulation of axonogenesis; GO:2000145 regulation of cell motility; GO:1902580 single-organism cellular localization; GO:0007275 multicellular organism development; GO:0034613 cellular protein localization; GO:0090150 establishment of protein localization to membrane; GO:0009966 regulation of signal transduction; GO:0006950 response to stress; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0071702 organic substance transport; GO:0030334 regulation of cell migration; GO:0030155 regulation of cell adhesion; GO:0050770 regulation of axonogenesis; GO:0045184 establishment of protein localization; GO:0072659 protein localization to plasma membrane; GO:0030111 regulation of Wnt signaling pathway; GO:0010976 positive regulation of neuron projection development; GO:0030516 regulation of axon extension; GO:0061024 membrane organization; GO:0030177 positive regulation of Wnt signaling pathway; GO:0061387 regulation of extent of cell growth; GO:0050769 positive regulation of neurogenesis; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:0006892 post-Golgi vesicle-mediated transport; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:0010810 regulation of cell-substrate adhesion; GO:0050793 regulation of developmental process; GO:0045666 positive regulation of neuron differentiation; GO:0010256 endomembrane system organization; GO:1903391 regulation of adherens junction organization; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0090109 regulation of cell-substrate junction assembly; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0009611 response to wounding; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0006893 Golgi to plasma membrane transport; GO:0010720 positive regulation of cell development; GO:0033036 macromolecule localization; GO:0032502 developmental process; GO:0048639 positive regulation of developmental growth; GO:0051962 positive regulation of nervous system development; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0198738 cell-cell signaling by wnt; GO:0050789 regulation of biological process; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0045664 regulation of neuron differentiation; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0016043 cellular component organization; GO:0040008 regulation of growth; GO:0010770 positive regulation of cell morphogenesis involved in differentiation; GO:0051893 regulation of focal adhesion assembly; GO:0048193 Golgi vesicle transport; GO:0031344 regulation of cell projection organization; GO:0044087 regulation of cellular component biogenesis; GO:0048638 regulation of developmental growth; GO:0050896 response to stimulus; GO:0030154 cell differentiation; GO:0008361 regulation of cell size; GO:0023056 positive regulation of signaling; GO:0043001 Golgi to plasma membrane protein transport; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0098876 vesicle-mediated transport to the plasma membrane; GO:0044802 single-organism membrane organization; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0070727 cellular macromolecule localization; GO:0042060 wound healing; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0090066 regulation of anatomical structure size; GO:0051128 regulation of cellular component organization; GO:0009967 positive regulation of signal transduction; GO:0040012 regulation of locomotion; GO:0022604 regulation of cell morphogenesis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; GO:0050767 regulation of neurogenesis; ","GO:0016020 membrane; GO:0005874 microtubule; GO:0071944 cell periphery; GO:0032587 ruffle membrane; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0099512 supramolecular fiber; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0098590 plasma membrane region; GO:0031256 leading edge membrane; GO:0015630 microtubule cytoskeleton; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0031252 cell leading edge; GO:0042995 cell projection; GO:0099513 polymeric cytoskeletal fiber; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044463 cell projection part; GO:0099081 supramolecular polymer; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0031253 cell projection membrane; GO:0001726 ruffle; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:0051015 actin filament binding; GO:0003723 RNA binding; GO:0043167 ion binding; GO:0044877 macromolecular complex binding; GO:0015631 tubulin binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0017111 nucleoside-triphosphatase activity; GO:0016887 ATPase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0050839 cell adhesion molecule binding; GO:0008092 cytoskeletal protein binding; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0008017 microtubule binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0003676 nucleic acid binding; GO:0003779 actin binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005509 calcium ion binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0032403 protein complex binding; ","K19827",null,null,"IPR003108; IPR011992; IPR001715; IPR002048; ","Gas2-related domain; EF-hand domain pair; Calponin homology domain; EF-hand domain; \r"]
["Q9UPT5","Exocyst complex component 7 OS=Homo sapiens OX=9606 GN=EXOC7","EXOC7",83.381,25.307,7.8,5,7,5,1.028,1.057,1.06,0.923,0.936,0.956,0.895,1.42E-3,"nucleus\r","GO:0050794 regulation of cellular process; GO:2000535 regulation of entry of bacterium into host cell; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0031329 regulation of cellular catabolic process; GO:0016192 vesicle-mediated transport; GO:0009894 regulation of catabolic process; GO:0043900 regulation of multi-organism process; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0071702 organic substance transport; GO:0031323 regulation of cellular metabolic process; GO:0010506 regulation of autophagy; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0045184 establishment of protein localization; GO:0016241 regulation of macroautophagy; GO:0006810 transport; GO:0050789 regulation of biological process; GO:1902578 single-organism localization; GO:0032940 secretion by cell; GO:0019222 regulation of metabolic process; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0051179 localization; GO:0009987 cellular process; GO:0006887 exocytosis; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005938 cell cortex; GO:0044450 microtubule organizing center part; GO:0071944 cell periphery; GO:0099568 cytoplasmic region; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0030426 growth cone; GO:0044424 intracellular part; GO:0000145 exocyst; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0005815 microtubule organizing center; GO:0015630 microtubule cytoskeleton; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0043005 neuron projection; GO:0097458 neuron part; GO:0099023 tethering complex; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0034451 centriolar satellite; GO:0005829 cytosol; GO:0030427 site of polarized growth; GO:0044463 cell projection part; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0044448 cell cortex part; GO:0005813 centrosome; GO:0032584 growth cone membrane; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0090723 growth cone part; ","GO:0005515 protein binding; GO:0005488 binding; ","K07195","EXOC7; exocyst complex component 7","hsa04910 Insulin signaling pathway - Homo sapiens (human); ","IPR016159; ","Cullin repeat-like-containing domain; \r"]
["Q9UPT8","Zinc finger CCCH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=ZC3H4","ZC3H4",140.26,3.2769,2,2,2,2,0.856,0.869,1.012,1.114,1.107,1.037,1.19,0.0385,"nucleus\r",null,null,"GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0043167 ion binding; GO:0043169 cation binding; GO:0046872 metal ion binding; ",{"$nulls":3},"IPR000571; ","\"Zinc finger, CCCH-type; \"\r"]
["Q9UPU5","Ubiquitin carboxyl-terminal hydrolase 24 OS=Homo sapiens OX=9606 GN=USP24","USP24",294.36,12.363,2.3,6,7,6,1.034,1.031,1.021,0.961,0.963,1,0.948,0.016,"cytoplasm\r","GO:0043632 modification-dependent macromolecule catabolic process; GO:0070646 protein modification by small protein removal; GO:0044265 cellular macromolecule catabolic process; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0019941 modification-dependent protein catabolic process; GO:0044267 cellular protein metabolic process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0016579 protein deubiquitination; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:1901575 organic substance catabolic process; GO:0008152 metabolic process; GO:0030163 protein catabolic process; GO:0009057 macromolecule catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0044248 cellular catabolic process; GO:0006464 cellular protein modification process; GO:0006508 proteolysis; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:0009987 cellular process; GO:0009056 catabolic process; ","GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0008233 peptidase activity; GO:0036459 thiol-dependent ubiquitinyl hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0101005 ubiquitinyl hydrolase activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0019783 ubiquitin-like protein-specific protease activity; GO:0005515 protein binding; GO:0008234 cysteine-type peptidase activity; GO:0016787 hydrolase activity; ","K11840",null,null,"IPR015940; IPR029071; IPR028889; IPR001394; IPR016024; IPR009060; ","\"Ubiquitin-associated domain; Ubiquitin-related domain; Ubiquitin specific protease domain; Peptidase C19, ubiquitin carboxyl-terminal hydrolase; Armadillo-type fold; UBA-like; \"\r"]
["Q9UPU7","TBC1 domain family member 2B OS=Homo sapiens OX=9606 GN=TBC1D2B","TBC1D2B",109.88,9.8677,4,4,4,4,1.196,1.07,1.003,0.773,0.917,1.056,0.84,0.158,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0060627 regulation of vesicle-mediated transport; GO:0046907 intracellular transport; GO:0043547 positive regulation of GTPase activity; GO:0051049 regulation of transport; GO:0033043 regulation of organelle organization; GO:0071702 organic substance transport; GO:0031338 regulation of vesicle fusion; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0051641 cellular localization; GO:0043085 positive regulation of catalytic activity; GO:0006810 transport; GO:0045184 establishment of protein localization; GO:0090630 activation of GTPase activity; GO:0070727 cellular macromolecule localization; GO:0050789 regulation of biological process; GO:0051649 establishment of localization in cell; GO:0051336 regulation of hydrolase activity; GO:0051345 positive regulation of hydrolase activity; GO:0032879 regulation of localization; GO:0050790 regulation of catalytic activity; GO:0044093 positive regulation of molecular function; GO:0006886 intracellular protein transport; GO:0043087 regulation of GTPase activity; GO:0065009 regulation of molecular function; GO:0051128 regulation of cellular component organization; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0034613 cellular protein localization; GO:0051179 localization; GO:0065007 biological regulation; ","GO:0012505 endomembrane system; GO:0005623 cell; GO:0005622 intracellular; GO:0044464 cell part; ","GO:0031267 small GTPase binding; GO:0030234 enzyme regulator activity; GO:0017016 Ras GTPase binding; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0005488 binding; GO:0030695 GTPase regulator activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0051020 GTPase binding; GO:0008047 enzyme activator activity; GO:0019899 enzyme binding; GO:0017137 Rab GTPase binding; GO:0005096 GTPase activator activity; ","K20166",null,null,"IPR011993; IPR000195; IPR001849; ","PH domain-like; Rab-GTPase-TBC domain; Pleckstrin homology domain; \r"]
["Q9UQ35","Serine/arginine repetitive matrix protein 2 OS=Homo sapiens OX=9606 GN=SRRM2","SRRM2",299.61,23.703,2.3,5,5,5,0.855,0.994,0.9,0.948,1.137,1.146,1.175,0.104,"nucleus\r","GO:0006396 RNA processing; GO:0006725 cellular aromatic compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0008152 metabolic process; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0090304 nucleic acid metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0016071 mRNA metabolic process; ","GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005681 spliceosomal complex; GO:0016604 nuclear body; GO:0005623 cell; GO:0015030 Cajal body; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0044464 cell part; GO:0005622 intracellular; GO:0071013 catalytic step 2 spliceosome; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0047485 protein N-terminus binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0070742 C2H2 zinc finger domain binding; GO:0005515 protein binding; GO:0019904 protein domain specific binding; ","K13172",null,null,"IPR024945; IPR013170; ","Spt5 C-terminal domain; mRNA splicing factor Cwf21 domain; \r"]
["Q9UQ80","Proliferation-associated protein 2G4 OS=Homo sapiens OX=9606 GN=PA2G4","PA2G4",43.786,179.04,49.5,17,39,17,0.836,0.866,0.845,1.119,1.108,1.176,1.336,1.63E-4,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0010941 regulation of cell death; GO:0045321 leukocyte activation; GO:0010608 posttranscriptional regulation of gene expression; GO:0097659 nucleic acid-templated transcription; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0051253 negative regulation of RNA metabolic process; GO:0051234 establishment of localization; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0006364 rRNA processing; GO:0043170 macromolecule metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0051726 regulation of cell cycle; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0016072 rRNA metabolic process; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0002443 leukocyte mediated immunity; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0042254 ribosome biogenesis; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0016070 RNA metabolic process; GO:0006810 transport; GO:1903506 regulation of nucleic acid-templated transcription; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0032940 secretion by cell; GO:1902679 negative regulation of RNA biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0043299 leukocyte degranulation; GO:0060548 negative regulation of cell death; GO:0051094 positive regulation of developmental process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0045786 negative regulation of cell cycle; GO:0043069 negative regulation of programmed cell death; GO:0002283 neutrophil activation involved in immune response; GO:0006725 cellular aromatic compound metabolic process; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0043067 regulation of programmed cell death; GO:0031324 negative regulation of cellular metabolic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0045597 positive regulation of cell differentiation; GO:0071704 organic substance metabolic process; GO:0045892 negative regulation of transcription, DNA-templated; GO:0046483 heterocycle metabolic process; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0043066 negative regulation of apoptotic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0036230 granulocyte activation; GO:0009059 macromolecule biosynthetic process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0007050 cell cycle arrest; GO:0016192 vesicle-mediated transport; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0008283 cell proliferation; GO:0010556 regulation of macromolecule biosynthetic process; GO:0002376 immune system process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0044238 primary metabolic process; GO:0043312 neutrophil degranulation; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0002263 cell activation involved in immune response; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0034248 regulation of cellular amide metabolic process; GO:0002366 leukocyte activation involved in immune response; GO:0009890 negative regulation of biosynthetic process; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0051246 regulation of protein metabolic process; GO:0006417 regulation of translation; GO:0001775 cell activation; GO:0010467 gene expression; GO:0031327 negative regulation of cellular biosynthetic process; GO:0022402 cell cycle process; GO:0006955 immune response; GO:0051179 localization; GO:0034660 ncRNA metabolic process; GO:0050793 regulation of developmental process; GO:0042981 regulation of apoptotic process; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:0006887 exocytosis; ","GO:0034774 secretory granule lumen; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005775 vacuolar lumen; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0005730 nucleolus; GO:0005576 extracellular region; GO:0042582 azurophil granule; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003677 DNA binding; GO:0003723 RNA binding; GO:0031625 ubiquitin protein ligase binding; GO:0005488 binding; GO:0001071 nucleic acid binding transcription factor activity; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0003700 transcription factor activity, sequence-specific DNA binding; GO:0019899 enzyme binding; ",{"$nulls":3},"IPR011991; IPR000994; ","Winged helix-turn-helix DNA-binding domain; Peptidase M24; \r"]
["Q9UQB8","Brain-specific angiogenesis inhibitor 1-associated protein 2 OS=Homo sapiens OX=9606 GN=BAIAP2","BAIAP2",60.867,32.978,17.2,9,9,9,0.889,0.908,0.948,1.031,1.109,1.116,1.186,0.00578,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0007166 cell surface receptor signaling pathway; GO:0007420 brain development; GO:0032989 cellular component morphogenesis; GO:0030832 regulation of actin filament length; GO:0009607 response to biotic stimulus; GO:0022610 biological adhesion; GO:0009605 response to external stimulus; GO:0030036 actin cytoskeleton organization; GO:0051240 positive regulation of multicellular organismal process; GO:0008360 regulation of cell shape; GO:0032535 regulation of cellular component size; GO:0007155 cell adhesion; GO:0009719 response to endogenous stimulus; GO:0070848 response to growth factor; GO:0051493 regulation of cytoskeleton organization; GO:0008104 protein localization; GO:1901652 response to peptide; GO:0044765 single-organism transport; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0031346 positive regulation of cell projection organization; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0048812 neuron projection morphogenesis; GO:0007009 plasma membrane organization; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:2000251 positive regulation of actin cytoskeleton reorganization; GO:0006810 transport; GO:0000902 cell morphogenesis; GO:0048513 animal organ development; GO:0010243 response to organonitrogen compound; GO:0071364 cellular response to epidermal growth factor stimulus; GO:0007417 central nervous system development; GO:0071230 cellular response to amino acid stimulus; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0032869 cellular response to insulin stimulus; GO:0060999 positive regulation of dendritic spine development; GO:0002682 regulation of immune system process; GO:1902905 positive regulation of supramolecular fiber organization; GO:0048010 vascular endothelial growth factor receptor signaling pathway; GO:0051094 positive regulation of developmental process; GO:0097435 supramolecular fiber organization; GO:0010975 regulation of neuron projection development; GO:1902903 regulation of supramolecular fiber organization; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0032956 regulation of actin cytoskeleton organization; GO:1901700 response to oxygen-containing compound; GO:0045597 positive regulation of cell differentiation; GO:0048814 regulation of dendrite morphogenesis; GO:0051239 regulation of multicellular organismal process; GO:1900006 positive regulation of dendrite development; GO:0009653 anatomical structure morphogenesis; GO:1902578 single-organism localization; GO:0071229 cellular response to acid chemical; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0007409 axonogenesis; GO:0007275 multicellular organism development; GO:0038093 Fc receptor signaling pathway; GO:0007010 cytoskeleton organization; GO:0050778 positive regulation of immune response; GO:0009966 regulation of signal transduction; GO:0009617 response to bacterium; GO:0048167 regulation of synaptic plasticity; GO:0002253 activation of immune response; GO:0051495 positive regulation of cytoskeleton organization; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0051960 regulation of nervous system development; GO:0060284 regulation of cell development; GO:0050804 modulation of synaptic transmission; GO:0002376 immune system process; GO:0032970 regulation of actin filament-based process; GO:0010033 response to organic substance; GO:0030838 positive regulation of actin filament polymerization; GO:0061572 actin filament bundle organization; GO:0008064 regulation of actin polymerization or depolymerization; GO:0030182 neuron differentiation; GO:0010976 positive regulation of neuron projection development; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0030029 actin filament-based process; GO:0050769 positive regulation of neurogenesis; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0030833 regulation of actin filament polymerization; GO:0001101 response to acid chemical; GO:0010256 endomembrane system organization; GO:0008286 insulin receptor signaling pathway; GO:0045666 positive regulation of neuron differentiation; GO:0032273 positive regulation of protein polymerization; GO:0098815 modulation of excitatory postsynaptic potential; GO:0038094 Fc-gamma receptor signaling pathway; GO:0048869 cellular developmental process; GO:0048666 neuron development; GO:0023051 regulation of signaling; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0071363 cellular response to growth factor stimulus; GO:0051234 establishment of localization; GO:0006909 phagocytosis; GO:0051130 positive regulation of cellular component organization; GO:0007165 signal transduction; GO:0050806 positive regulation of synaptic transmission; GO:0010646 regulation of cell communication; GO:1901653 cellular response to peptide; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0032990 cell part morphogenesis; GO:2000463 positive regulation of excitatory postsynaptic potential; GO:0032271 regulation of protein polymerization; GO:0048858 cell projection morphogenesis; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0031334 positive regulation of protein complex assembly; GO:0060322 head development; GO:0033036 macromolecule localization; GO:0010720 positive regulation of cell development; GO:0070887 cellular response to chemical stimulus; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0032502 developmental process; GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis; GO:0043200 response to amino acid; GO:0060998 regulation of dendritic spine development; GO:0098609 cell-cell adhesion; GO:0051962 positive regulation of nervous system development; GO:0048522 positive regulation of cellular process; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0042391 regulation of membrane potential; GO:0071417 cellular response to organonitrogen compound; GO:1902589 single-organism organelle organization; GO:0043254 regulation of protein complex assembly; GO:0050789 regulation of biological process; GO:0032868 response to insulin; GO:0042221 response to chemical; GO:0043434 response to peptide hormone; GO:1902065 response to L-glutamate; GO:0010638 positive regulation of organelle organization; GO:0045664 regulation of neuron differentiation; GO:0030030 cell projection organization; GO:1901699 cellular response to nitrogen compound; GO:1905232 cellular response to L-glutamate; GO:0032870 cellular response to hormone stimulus; GO:0002431 Fc receptor mediated stimulatory signaling pathway; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0016043 cellular component organization; GO:0016358 dendrite development; GO:0035418 protein localization to synapse; GO:0061001 regulation of dendritic spine morphogenesis; GO:0002252 immune effector process; GO:0071310 cellular response to organic substance; GO:0007015 actin filament organization; GO:0010770 positive regulation of cell morphogenesis involved in differentiation; GO:0044087 regulation of cellular component biogenesis; GO:0031344 regulation of cell projection organization; GO:0043207 response to external biotic stimulus; GO:0051017 actin filament bundle assembly; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0048468 cell development; GO:0000904 cell morphogenesis involved in differentiation; GO:0030154 cell differentiation; GO:0023056 positive regulation of signaling; GO:2000249 regulation of actin cytoskeleton reorganization; GO:0071375 cellular response to peptide hormone stimulus; GO:0002757 immune response-activating signal transduction; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:0061003 positive regulation of dendritic spine morphogenesis; GO:0045595 regulation of cell differentiation; GO:0051764 actin crosslink formation; GO:0070849 response to epidermal growth factor; GO:0044802 single-organism membrane organization; GO:0033043 regulation of organelle organization; GO:0006897 endocytosis; GO:0031175 neuron projection development; GO:0048518 positive regulation of biological process; GO:0050775 positive regulation of dendrite morphogenesis; GO:0061564 axon development; GO:1901701 cellular response to oxygen-containing compound; GO:0071495 cellular response to endogenous stimulus; GO:0044767 single-organism developmental process; GO:0002684 positive regulation of immune system process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0090066 regulation of anatomical structure size; GO:0050773 regulation of dendrite development; GO:0051128 regulation of cellular component organization; GO:0009967 positive regulation of signal transduction; GO:0009725 response to hormone; GO:0022604 regulation of cell morphogenesis; GO:0044089 positive regulation of cellular component biogenesis; GO:0050767 regulation of neurogenesis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0030425 dendrite; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0060076 excitatory synapse; GO:0005737 cytoplasm; GO:0043025 neuronal cell body; GO:0005913 cell-cell adherens junction; GO:0098858 actin-based cell projection; GO:0005623 cell; GO:0099080 supramolecular complex; GO:0043197 dendritic spine; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0098590 plasma membrane region; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0014069 postsynaptic density; GO:0030175 filopodium; GO:0097060 synaptic membrane; GO:0043005 neuron projection; GO:0044306 neuron projection terminus; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0031252 cell leading edge; GO:0042995 cell projection; GO:0099513 polymeric cytoskeletal fiber; GO:0005791 rough endoplasmic reticulum; GO:0044430 cytoskeletal part; GO:0070161 anchoring junction; GO:0005576 extracellular region; GO:0033267 axon part; GO:0005886 plasma membrane; GO:0099081 supramolecular polymer; GO:0030424 axon; GO:0043231 intracellular membrane-bounded organelle; GO:0098794 postsynapse; GO:0043195 terminal bouton; GO:0099572 postsynaptic specialization; GO:0043230 extracellular organelle; GO:0005783 endoplasmic reticulum; GO:0005874 microtubule; GO:0031410 cytoplasmic vesicle; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0005911 cell-cell junction; GO:0043679 axon terminus; GO:0032279 asymmetric synapse; GO:0005856 cytoskeleton; GO:0044309 neuron spine; GO:0015630 microtubule cytoskeleton; GO:0098793 presynapse; GO:0044464 cell part; GO:0044425 membrane part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0098984 neuron to neuron synapse; GO:0044456 synapse part; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0045202 synapse; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0044459 plasma membrane part; GO:0001726 ruffle; GO:0043198 dendritic shaft; GO:0044297 cell body; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:0030674 protein binding, bridging; GO:0097110 scaffold protein binding; GO:0005515 protein binding; GO:0098632 protein binding involved in cell-cell adhesion; GO:0030165 PDZ domain binding; GO:0070064 proline-rich region binding; GO:0050839 cell adhesion molecule binding; GO:0098641 cadherin binding involved in cell-cell adhesion; GO:0008092 cytoskeletal protein binding; GO:0042802 identical protein binding; GO:0098631 protein binding involved in cell adhesion; GO:0008093 cytoskeletal adaptor activity; GO:0005488 binding; GO:0045296 cadherin binding; GO:0001221 transcription cofactor binding; GO:0008022 protein C-terminus binding; GO:0019904 protein domain specific binding; GO:0060090 binding, bridging; GO:0008134 transcription factor binding; ","K05627","BAIAP2; BAI1-associated protein 2","hsa04520 Adherens junction - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); ","IPR001452; IPR013606; ","SH3 domain; IMD/I-BAR domain; \r"]
["Q9UQC9","Calcium-activated chloride channel regulator 2 OS=Homo sapiens OX=9606 GN=CLCA2","CLCA2",103.94,15.385,4.5,4,6,4,0.895,0.747,0.715,1.202,1.226,1.302,1.583,0.00312,"plasma membrane\r","GO:0098661 inorganic anion transmembrane transport; GO:0034220 ion transmembrane transport; GO:0098660 inorganic ion transmembrane transport; GO:0006821 chloride transport; GO:0044238 primary metabolic process; GO:0098656 anion transmembrane transport; GO:0071704 organic substance metabolic process; GO:1902476 chloride transmembrane transport; GO:0051234 establishment of localization; GO:0006810 transport; GO:0006820 anion transport; GO:0055085 transmembrane transport; GO:0022610 biological adhesion; GO:0008152 metabolic process; GO:0006811 ion transport; GO:0007155 cell adhesion; GO:0006508 proteolysis; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0051179 localization; GO:0015698 inorganic anion transport; ","GO:0016323 basolateral plasma membrane; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0031226 intrinsic component of plasma membrane; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0098590 plasma membrane region; GO:0044459 plasma membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0009925 basal plasma membrane; GO:0043227 membrane-bounded organelle; GO:0045178 basal part of cell; ","GO:0022839 ion gated channel activity; GO:0008233 peptidase activity; GO:0022803 passive transmembrane transporter activity; GO:0061778 intracellular chloride channel activity; GO:0022892 substrate-specific transporter activity; GO:0016787 hydrolase activity; GO:0015103 inorganic anion transmembrane transporter activity; GO:0015267 channel activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0005229 intracellular calcium activated chloride channel activity; GO:0043169 cation binding; GO:0005216 ion channel activity; GO:0005215 transporter activity; GO:0015276 ligand-gated ion channel activity; GO:0022834 ligand-gated channel activity; GO:0004222 metalloendopeptidase activity; GO:0015075 ion transmembrane transporter activity; GO:0043167 ion binding; GO:0005253 anion channel activity; GO:0008237 metallopeptidase activity; GO:0005254 chloride channel activity; GO:0004175 endopeptidase activity; GO:0015108 chloride transmembrane transporter activity; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0022838 substrate-specific channel activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0046872 metal ion binding; GO:0022836 gated channel activity; GO:0099600 transmembrane receptor activity; GO:0022857 transmembrane transporter activity; GO:0008509 anion transmembrane transporter activity; ","K05028","CLCA2; calcium-activated chloride channel regulator 2","hsa04924 Renin secretion - Homo sapiens (human); hsa04972 Pancreatic secretion - Homo sapiens (human); ","IPR002035; ","\"von Willebrand factor, type A; \"\r"]
["Q9UQE7","Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3","SMC3",141.54,49.617,7.5,8,9,8,0.937,0.985,1.027,0.97,0.967,1.031,1.006,0.853,"cytoplasm\r","GO:0044700 single organism signaling; GO:0022414 reproductive process; GO:0007067 mitotic nuclear division; GO:0044699 single-organism process; GO:0090329 regulation of DNA-dependent DNA replication; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0000819 sister chromatid segregation; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0044702 single organism reproductive process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0043170 macromolecule metabolic process; GO:0051726 regulation of cell cycle; GO:0032502 developmental process; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0007059 chromosome segregation; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0051321 meiotic cell cycle; GO:0023052 signaling; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0032501 multicellular organismal process; GO:0008156 negative regulation of DNA replication; GO:1902589 single-organism organelle organization; GO:0010948 negative regulation of cell cycle process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0051052 regulation of DNA metabolic process; GO:0051053 negative regulation of DNA metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0098727 maintenance of cell number; GO:0019222 regulation of metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0051301 cell division; GO:2000104 negative regulation of DNA-dependent DNA replication; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0000003 reproduction; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0033554 cellular response to stress; GO:0045786 negative regulation of cell cycle; GO:1903046 meiotic cell cycle process; GO:0006275 regulation of DNA replication; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0006259 DNA metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0048285 organelle fission; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:1903047 mitotic cell cycle process; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0019827 stem cell population maintenance; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0009987 cellular process; GO:0032875 regulation of DNA endoreduplication; GO:0006950 response to stress; GO:0000070 mitotic sister chromatid segregation; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0006974 cellular response to DNA damage stimulus; GO:0007064 mitotic sister chromatid cohesion; GO:0009890 negative regulation of biosynthetic process; GO:0006281 DNA repair; GO:0051276 chromosome organization; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0098813 nuclear chromosome segregation; GO:0000280 nuclear division; GO:0007126 meiotic nuclear division; GO:0031327 negative regulation of cellular biosynthetic process; GO:0022402 cell cycle process; GO:0007062 sister chromatid cohesion; GO:0032876 negative regulation of DNA endoreduplication; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0030893 meiotic cohesin complex; GO:0005623 cell; GO:0044420 extracellular matrix component; GO:0044422 organelle part; GO:0005604 basement membrane; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0031974 membrane-enclosed lumen; GO:0000793 condensed chromosome; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0044454 nuclear chromosome part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0034991 nuclear meiotic cohesin complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0000922 spindle pole; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0000798 nuclear cohesin complex; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005819 spindle; GO:0005576 extracellular region; GO:0099086 synaptonemal structure; GO:0008278 cohesin complex; GO:0098687 chromosomal region; GO:0043226 organelle; GO:0031012 extracellular matrix; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0000785 chromatin; GO:0016363 nuclear matrix; GO:0000800 lateral element; GO:0000775 chromosome, centromeric region; GO:0005578 proteinaceous extracellular matrix; GO:0000228 nuclear chromosome; GO:0034399 nuclear periphery; GO:0000794 condensed nuclear chromosome; GO:0043234 protein complex; GO:0000795 synaptonemal complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0070840 dynein complex binding; GO:1901265 nucleoside phosphate binding; GO:0003774 motor activity; GO:0046983 protein dimerization activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0003682 chromatin binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0003777 microtubule motor activity; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0046982 protein heterodimerization activity; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0036033 mediator complex binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; GO:0032403 protein complex binding; ","K06669","SMC3; structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6)","hsa04110 Cell cycle - Homo sapiens (human); hsa04114 Oocyte meiosis - Homo sapiens (human); ","IPR010935; IPR027417; IPR003395; ","\"SMCs flexible hinge; P-loop containing nucleoside triphosphate hydrolase; RecF/RecN/SMC, N-terminal; \"\r"]
["Q9UQN3","Charged multivesicular body protein 2b OS=Homo sapiens OX=9606 GN=CHMP2B","CHMP2B",23.906,5.9876,8.9,2,3,2,0.892,0.907,0.988,1.095,1.04,1.077,1.152,0.0153,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0006914 autophagy; GO:0044237 cellular metabolic process; GO:0010564 regulation of cell cycle process; GO:0050877 neurological system process; GO:0015031 protein transport; GO:0008152 metabolic process; GO:0010824 regulation of centrosome duplication; GO:0036258 multivesicular body assembly; GO:0051493 regulation of cytoskeleton organization; GO:0044801 single-organism membrane fusion; GO:0008104 protein localization; GO:0044419 interspecies interaction between organisms; GO:0000278 mitotic cell cycle; GO:0007059 chromosome segregation; GO:1901673 regulation of mitotic spindle assembly; GO:0007088 regulation of mitotic nuclear division; GO:0044763 single-organism cellular process; GO:0039702 viral budding via host ESCRT complex; GO:0061025 membrane fusion; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0008333 endosome to lysosome transport; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0032886 regulation of microtubule-based process; GO:0051301 cell division; GO:0046605 regulation of centrosome cycle; GO:0050794 regulation of cellular process; GO:0051640 organelle localization; GO:0090174 organelle membrane fusion; GO:0046907 intracellular transport; GO:0007346 regulation of mitotic cell cycle; GO:0032509 endosome transport via multivesicular body sorting pathway; GO:0000920 cell separation after cytokinesis; GO:0007080 mitotic metaphase plate congression; GO:1903047 mitotic cell cycle process; GO:0060249 anatomical structure homeostasis; GO:0044248 cellular catabolic process; GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway; GO:0016192 vesicle-mediated transport; GO:0043900 regulation of multi-organism process; GO:0032984 macromolecular complex disassembly; GO:0048284 organelle fusion; GO:0071702 organic substance transport; GO:1902188 positive regulation of viral release from host cell; GO:0051656 establishment of organelle localization; GO:0045184 establishment of protein localization; GO:1902186 regulation of viral release from host cell; GO:0090224 regulation of spindle organization; GO:0051276 chromosome organization; GO:0098813 nuclear chromosome segregation; GO:0006996 organelle organization; GO:0006900 membrane budding; GO:0061024 membrane organization; GO:0000280 nuclear division; GO:0051179 localization; GO:0010256 endomembrane system organization; GO:0040017 positive regulation of locomotion; GO:0007067 mitotic nuclear division; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0060236 regulation of mitotic spindle organization; GO:1902115 regulation of organelle assembly; GO:0051234 establishment of localization; GO:0043241 protein complex disassembly; GO:0051783 regulation of nuclear division; GO:0000819 sister chromatid segregation; GO:0050000 chromosome localization; GO:0051649 establishment of localization in cell; GO:0022607 cellular component assembly; GO:1904896 ESCRT complex disassembly; GO:0070050 neuron cellular homeostasis; GO:0033036 macromolecule localization; GO:0051726 regulation of cell cycle; GO:0016236 macroautophagy; GO:1903902 positive regulation of viral life cycle; GO:0043902 positive regulation of multi-organism process; GO:0071822 protein complex subunit organization; GO:0048522 positive regulation of cellular process; GO:0019725 cellular homeostasis; GO:0036257 multivesicular body organization; GO:0016197 endosomal transport; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0061763 multivesicular body-lysosome fusion; GO:0006997 nucleus organization; GO:0016043 cellular component organization; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0019068 virion assembly; GO:0019058 viral life cycle; GO:0048285 organelle fission; GO:1902592 multi-organism membrane budding; GO:0044087 regulation of cellular component biogenesis; GO:0051310 metaphase plate congression; GO:0042592 homeostatic process; GO:0070925 organelle assembly; GO:0016032 viral process; GO:0050890 cognition; GO:0009987 cellular process; GO:0007041 lysosomal transport; GO:0070507 regulation of microtubule cytoskeleton organization; GO:0003008 system process; GO:0051303 establishment of chromosome localization; GO:0044803 multi-organism membrane organization; GO:0050792 regulation of viral process; GO:0016050 vesicle organization; GO:0033043 regulation of organelle organization; GO:0000070 mitotic sister chromatid segregation; GO:0044802 single-organism membrane organization; GO:0048518 positive regulation of biological process; GO:1902590 multi-organism organelle organization; GO:0051641 cellular localization; GO:0043933 macromolecular complex subunit organization; GO:0090169 regulation of spindle assembly; GO:0048524 positive regulation of viral process; GO:0046755 viral budding; GO:0007034 vacuolar transport; GO:1904903 ESCRT III complex disassembly; GO:0022411 cellular component disassembly; GO:0051128 regulation of cellular component organization; GO:0022402 cell cycle process; GO:1903900 regulation of viral life cycle; GO:0040012 regulation of locomotion; GO:0009056 catabolic process; GO:0007032 endosome organization; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0036452 ESCRT complex; GO:0044425 membrane part; GO:0031902 late endosome membrane; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0000815 ESCRT III complex; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0010008 endosome membrane; GO:0005770 late endosome; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0050839 cell adhesion molecule binding; GO:0019904 protein domain specific binding; GO:0005515 protein binding; GO:0005488 binding; GO:0045296 cadherin binding; ","K12192","CHMP2B; charged multivesicular body protein 2B","hsa04144 Endocytosis - Homo sapiens (human); hsa04217 Necroptosis - Homo sapiens (human); "]
["Q9Y224","RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF","RTRAF",28.068,68.556,41.8,9,10,9,0.982,1.007,1.012,1.033,0.99,0.968,0.997,0.873,"cytoplasm\r","GO:0050658 RNA transport; GO:0097659 nucleic acid-templated transcription; GO:0009891 positive regulation of biosynthetic process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0009893 positive regulation of metabolic process; GO:0050657 nucleic acid transport; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0015931 nucleobase-containing compound transport; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0033036 macromolecule localization; GO:0034470 ncRNA processing; GO:0006396 RNA processing; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0051704 multi-organism process; GO:0016070 RNA metabolic process; GO:0006810 transport; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0008033 tRNA processing; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0051236 establishment of RNA localization; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0016032 viral process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0051254 positive regulation of RNA metabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0006403 RNA localization; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0000394 RNA splicing, via endonucleolytic cleavage and ligation; GO:0006399 tRNA metabolic process; GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0031325 positive regulation of cellular metabolic process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0010467 gene expression; GO:0031328 positive regulation of cellular biosynthetic process; GO:0051179 localization; GO:0034660 ncRNA metabolic process; GO:0071705 nitrogen compound transport; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005856 cytoskeleton; GO:0005815 microtubule organizing center; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0072669 tRNA-splicing ligase complex; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0048471 perinuclear region of cytoplasm; GO:0043227 membrane-bounded organelle; GO:0043234 protein complex; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0003723 RNA binding; GO:0001099 basal RNA polymerase II transcription machinery binding; GO:0000993 RNA polymerase II core binding; GO:0044877 macromolecular complex binding; GO:0005515 protein binding; GO:0070063 RNA polymerase binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0043175 RNA polymerase core enzyme binding; GO:0042802 identical protein binding; GO:0001098 basal transcription machinery binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0019899 enzyme binding; GO:0032403 protein complex binding; ","K15433"]
["Q9Y230","RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2","RUVBL2",51.156,82.028,37.4,16,24,16,0.923,0.952,0.927,1.065,1.043,1.067,1.133,0.000499,"cytoplasm\r","GO:0032270 positive regulation of cellular protein metabolic process; GO:0097659 nucleic acid-templated transcription; GO:0009891 positive regulation of biosynthetic process; GO:0034644 cellular response to UV; GO:0032091 negative regulation of protein binding; GO:0044237 cellular metabolic process; GO:1905269 positive regulation of chromatin organization; GO:0008152 metabolic process; GO:0032879 regulation of localization; GO:1904874 positive regulation of telomerase RNA localization to Cajal body; GO:0071733 transcriptional activation by promoter-enhancer looping; GO:0033365 protein localization to organelle; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0008104 protein localization; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0071214 cellular response to abiotic stimulus; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0071396 cellular response to lipid; GO:0071169 establishment of protein localization to chromatin; GO:0071482 cellular response to light stimulus; GO:1903506 regulation of nucleic acid-templated transcription; GO:0006473 protein acetylation; GO:2001252 positive regulation of chromosome organization; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:1901362 organic cyclic compound biosynthetic process; GO:0071392 cellular response to estradiol stimulus; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0034502 protein localization to chromosome; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0006338 chromatin remodeling; GO:0006259 DNA metabolic process; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0016570 histone modification; GO:1901700 response to oxygen-containing compound; GO:0044267 cellular protein metabolic process; GO:0032355 response to estradiol; GO:1901985 positive regulation of protein acetylation; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0016569 covalent chromatin modification; GO:0034613 cellular protein localization; GO:1904872 regulation of telomerase RNA localization to Cajal body; GO:0051254 positive regulation of RNA metabolic process; GO:0006950 response to stress; GO:0009416 response to light stimulus; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1902275 regulation of chromatin organization; GO:0071407 cellular response to organic cyclic compound; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0071898 regulation of estrogen receptor binding; GO:0006974 cellular response to DNA damage stimulus; GO:0033044 regulation of chromosome organization; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0045184 establishment of protein localization; GO:1900121 negative regulation of receptor binding; GO:0071168 protein localization to chromatin; GO:2000758 positive regulation of peptidyl-lysine acetylation; GO:0051247 positive regulation of protein metabolic process; GO:0051276 chromosome organization; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0051179 localization; GO:0031328 positive regulation of cellular biosynthetic process; GO:0043412 macromolecule modification; GO:0072594 establishment of protein localization to organelle; GO:0032392 DNA geometric change; GO:0009058 biosynthetic process; GO:0051234 establishment of localization; GO:0006457 protein folding; GO:0051130 positive regulation of cellular component organization; GO:0090202 gene looping; GO:2001141 regulation of RNA biosynthetic process; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0043543 protein acylation; GO:0009314 response to radiation; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0033036 macromolecule localization; GO:0070887 cellular response to chemical stimulus; GO:0006310 DNA recombination; GO:0071103 DNA conformation change; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0018394 peptidyl-lysine acetylation; GO:0070199 establishment of protein localization to chromosome; GO:0051098 regulation of binding; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0043967 histone H4 acetylation; GO:0090579 dsDNA loop formation; GO:0035066 positive regulation of histone acetylation; GO:0016070 RNA metabolic process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0016573 histone acetylation; GO:0051100 negative regulation of binding; GO:0010638 positive regulation of organelle organization; GO:1901983 regulation of protein acetylation; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0006325 chromatin organization; GO:0036211 protein modification process; GO:2000756 regulation of peptidyl-lysine acetylation; GO:0018393 internal peptidyl-lysine acetylation; GO:0031056 regulation of histone modification; GO:0016043 cellular component organization; GO:0040008 regulation of growth; GO:0043968 histone H2A acetylation; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0018205 peptidyl-lysine modification; GO:0033993 response to lipid; GO:0071899 negative regulation of estrogen receptor binding; GO:0043393 regulation of protein binding; GO:0035065 regulation of histone acetylation; GO:0031058 positive regulation of histone modification; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:1900120 regulation of receptor binding; GO:0071478 cellular response to radiation; GO:0009987 cellular process; GO:0006475 internal protein amino acid acetylation; GO:0006355 regulation of transcription, DNA-templated; GO:0032508 DNA duplex unwinding; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0006807 nitrogen compound metabolic process; GO:0033043 regulation of organelle organization; GO:0031401 positive regulation of protein modification process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0018193 peptidyl-amino acid modification; GO:0006281 DNA repair; GO:0070727 cellular macromolecule localization; GO:1901701 cellular response to oxygen-containing compound; GO:0009411 response to UV; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0051246 regulation of protein metabolic process; GO:0010467 gene expression; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0051128 regulation of cellular component organization; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0005623 cell; GO:0070603 SWI/SNF superfamily-type complex; GO:0000123 histone acetyltransferase complex; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0035267 NuA4 histone acetyltransferase complex; GO:0070062 extracellular exosome; GO:0005654 nucleoplasm; GO:0005622 intracellular; GO:0044454 nuclear chromosome part; GO:0000790 nuclear chromatin; GO:0071339 MLL1 complex; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0033202 DNA helicase complex; GO:0000791 euchromatin; GO:0044665 MLL1/2 complex; GO:0044430 cytoskeletal part; GO:0031011 Ino80 complex; GO:0031981 nuclear lumen; GO:0035097 histone methyltransferase complex; GO:1902562 H4 histone acetyltransferase complex; GO:0005576 extracellular region; GO:0034708 methyltransferase complex; GO:0043231 intracellular membrane-bounded organelle; GO:0000785 chromatin; GO:1990904 ribonucleoprotein complex; GO:0034399 nuclear periphery; GO:0030529 intracellular ribonucleoprotein complex; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0097255 R2TP complex; GO:0000812 Swr1 complex; GO:0031982 vesicle; GO:0097346 INO80-type complex; GO:0044424 intracellular part; GO:0043189 H4/H2A histone acetyltransferase complex; GO:0044427 chromosomal part; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:1902494 catalytic complex; GO:0005815 microtubule organizing center; GO:0070013 intracellular organelle lumen; GO:0031248 protein acetyltransferase complex; GO:0015630 microtubule cytoskeleton; GO:0044464 cell part; GO:0005694 chromosome; GO:1903561 extracellular vesicle; GO:1902493 acetyltransferase complex; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:1990234 transferase complex; GO:0005829 cytosol; GO:0043226 organelle; GO:0005634 nucleus; GO:0005813 centrosome; GO:0016363 nuclear matrix; GO:0000228 nuclear chromosome; GO:0005719 nuclear euchromatin; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0008026 ATP-dependent helicase activity; GO:0035326 enhancer binding; GO:0000975 regulatory region DNA binding; GO:0097159 organic cyclic compound binding; GO:0042802 identical protein binding; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0001085 RNA polymerase II transcription factor binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0004003 ATP-dependent DNA helicase activity; GO:0043531 ADP binding; GO:0043168 anion binding; GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0043141 ATP-dependent 5'-3' DNA helicase activity; GO:0008094 DNA-dependent ATPase activity; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003677 DNA binding; GO:0005524 ATP binding; GO:0070035 purine NTP-dependent helicase activity; GO:0001099 basal RNA polymerase II transcription machinery binding; GO:0001012 RNA polymerase II regulatory region DNA binding; GO:0001882 nucleoside binding; GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding; GO:0000166 nucleotide binding; GO:0043565 sequence-specific DNA binding; GO:0017111 nucleoside-triphosphatase activity; GO:0001067 regulatory region nucleic acid binding; GO:0001098 basal transcription machinery binding; GO:0042803 protein homodimerization activity; GO:0044212 transcription regulatory region DNA binding; GO:0003676 nucleic acid binding; GO:0051082 unfolded protein binding; GO:0008134 transcription factor binding; GO:0001094 TFIID-class transcription factor binding; GO:1901265 nucleoside phosphate binding; GO:0031490 chromatin DNA binding; GO:0001158 enhancer sequence-specific DNA binding; GO:0003690 double-stranded DNA binding; GO:0046983 protein dimerization activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0003682 chromatin binding; GO:0016887 ATPase activity; GO:0001047 core promoter binding; GO:1901363 heterocyclic compound binding; GO:0001046 core promoter sequence-specific DNA binding; GO:0016462 pyrophosphatase activity; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding; GO:0003678 DNA helicase activity; GO:0017076 purine nucleotide binding; GO:0004386 helicase activity; GO:0000976 transcription regulatory region sequence-specific DNA binding; GO:0051117 ATPase binding; GO:0043167 ion binding; GO:1990837 sequence-specific double-stranded DNA binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0042623 ATPase activity, coupled; GO:0001091 RNA polymerase II basal transcription factor binding; GO:0043139 5'-3' DNA helicase activity; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019899 enzyme binding; GO:0036094 small molecule binding; ","K11338",null,null,"IPR003593; IPR010339; IPR027417; ","\"AAA+ ATPase domain; TIP49, C-terminal; P-loop containing nucleoside triphosphate hydrolase; \"\r"]
["Q9Y262","Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L","EIF3L",66.726,86.576,27.5,13,18,13,0.88,0.921,0.951,1.112,1.121,1.086,1.206,0.00154,"cytoplasm\r","GO:0075525 viral translational termination-reinitiation; GO:0019081 viral translation; GO:0006518 peptide metabolic process; GO:0019058 viral life cycle; GO:0044267 cellular protein metabolic process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0016032 viral process; GO:0006413 translational initiation; GO:0019080 viral gene expression; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006412 translation; GO:0009059 macromolecule biosynthetic process; GO:0044419 interspecies interaction between organisms; GO:0009987 cellular process; GO:0043043 peptide biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0043603 cellular amide metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0051704 multi-organism process; GO:0044249 cellular biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044452 nucleolar part; GO:0044424 intracellular part; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0005623 cell; GO:0001650 fibrillar center; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0005852 eukaryotic translation initiation factor 3 complex; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0008135 translation factor activity, RNA binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0003743 translation initiation factor activity; GO:0005515 protein binding; ","K15029",null,null,"IPR011990; ","Tetratricopeptide-like helical domain; \r"]
["Q9Y263","Phospholipase A-2-activating protein OS=Homo sapiens OX=9606 GN=PLAA","PLAA",87.156,48.021,19,13,15,13,0.904,0.995,0.93,1.12,1.088,0.973,1.124,0.0868,"mitochondria\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0010498 proteasomal protein catabolic process; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0044093 positive regulation of molecular function; GO:0044248 cellular catabolic process; GO:0006508 proteolysis; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0010992 ubiquitin homeostasis; GO:0009987 cellular process; GO:0006629 lipid metabolic process; GO:0043632 modification-dependent macromolecule catabolic process; GO:0051716 cellular response to stimulus; GO:0044265 cellular macromolecule catabolic process; GO:0006950 response to stress; GO:0019941 modification-dependent protein catabolic process; GO:0044763 single-organism cellular process; GO:0019725 cellular homeostasis; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0023052 signaling; GO:0044238 primary metabolic process; GO:0043085 positive regulation of catalytic activity; GO:1901575 organic substance catabolic process; GO:0050789 regulation of biological process; GO:0006793 phosphorus metabolic process; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0030163 protein catabolic process; GO:0006954 inflammatory response; GO:0009057 macromolecule catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0065009 regulation of molecular function; GO:0019637 organophosphate metabolic process; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0006644 phospholipid metabolic process; GO:0006952 defense response; GO:0009056 catabolic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0030234 enzyme regulator activity; GO:0005488 binding; GO:0060229 lipase activator activity; GO:0043130 ubiquitin binding; GO:0016005 phospholipase A2 activator activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0016004 phospholipase activator activity; GO:0008047 enzyme activator activity; GO:0032182 ubiquitin-like protein binding; ","K14018","PLAA; phospholipase A-2-activating protein","hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); ","IPR015155; IPR017986; IPR015943; IPR016024; IPR013535; ","\"PLAA family ubiquitin binding, PFU; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain; Armadillo-type fold; PUL domain; \"\r"]
["Q9Y265","RuvB-like 1 OS=Homo sapiens OX=9606 GN=RUVBL1","RUVBL1",50.227,165.91,40.6,13,23,13,0.918,0.951,0.92,1.083,1.045,1.079,1.15,0.000976,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:1903955 positive regulation of protein targeting to mitochondrion; GO:0022414 reproductive process; GO:0097659 nucleic acid-templated transcription; GO:1903533 regulation of protein targeting; GO:0044237 cellular metabolic process; GO:0010821 regulation of mitochondrion organization; GO:0008152 metabolic process; GO:0006334 nucleosome assembly; GO:0034724 DNA replication-independent nucleosome organization; GO:0065003 macromolecular complex assembly; GO:1903747 regulation of establishment of protein localization to mitochondrion; GO:0032879 regulation of localization; GO:0044702 single organism reproductive process; GO:1904837 beta-catenin-TCF complex assembly; GO:1904874 positive regulation of telomerase RNA localization to Cajal body; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0051716 cellular response to stimulus; GO:0000278 mitotic cell cycle; GO:0018130 heterocycle biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0034508 centromere complex assembly; GO:0019953 sexual reproduction; GO:0044763 single-organism cellular process; GO:0032774 RNA biosynthetic process; GO:0043044 ATP-dependent chromatin remodeling; GO:0031323 regulation of cellular metabolic process; GO:0010506 regulation of autophagy; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0065004 protein-DNA complex assembly; GO:1903506 regulation of nucleic acid-templated transcription; GO:0006473 protein acetylation; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0051223 regulation of protein transport; GO:0051301 cell division; GO:0034080 CENP-A containing nucleosome assembly; GO:0048609 multicellular organismal reproductive process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0000003 reproduction; GO:0050794 regulation of cellular process; GO:0034728 nucleosome organization; GO:0033554 cellular response to stress; GO:0006338 chromatin remodeling; GO:0043486 histone exchange; GO:0006259 DNA metabolic process; GO:0016570 histone modification; GO:0044267 cellular protein metabolic process; GO:1903047 mitotic cell cycle process; GO:0060341 regulation of cellular localization; GO:0006323 DNA packaging; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0032880 regulation of protein localization; GO:0016569 covalent chromatin modification; GO:0006336 DNA replication-independent nucleosome assembly; GO:0006461 protein complex assembly; GO:1904872 regulation of telomerase RNA localization to Cajal body; GO:0006950 response to stress; GO:0007283 spermatogenesis; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0006974 cellular response to DNA damage stimulus; GO:0031055 chromatin remodeling at centromere; GO:1904951 positive regulation of establishment of protein localization; GO:0051276 chromosome organization; GO:0006996 organelle organization; GO:0000280 nuclear division; GO:0043412 macromolecule modification; GO:1903827 regulation of cellular protein localization; GO:0070646 protein modification by small protein removal; GO:0007067 mitotic nuclear division; GO:0032392 DNA geometric change; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:1903749 positive regulation of establishment of protein localization to mitochondrion; GO:0051130 positive regulation of cellular component organization; GO:2001141 regulation of RNA biosynthetic process; GO:0022607 cellular component assembly; GO:0043543 protein acylation; GO:0031497 chromatin assembly; GO:0006310 DNA recombination; GO:0071824 protein-DNA complex subunit organization; GO:0071103 DNA conformation change; GO:0006333 chromatin assembly or disassembly; GO:0010468 regulation of gene expression; GO:0071822 protein complex subunit organization; GO:0031326 regulation of cellular biosynthetic process; GO:0018394 peptidyl-lysine acetylation; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0032386 regulation of intracellular transport; GO:0043967 histone H4 acetylation; GO:0070647 protein modification by small protein conjugation or removal; GO:0051050 positive regulation of transport; GO:0016070 RNA metabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0010638 positive regulation of organelle organization; GO:0016573 histone acetylation; GO:0019222 regulation of metabolic process; GO:0006325 chromatin organization; GO:0036211 protein modification process; GO:0070271 protein complex biogenesis; GO:0051222 positive regulation of protein transport; GO:0018393 internal peptidyl-lysine acetylation; GO:0016043 cellular component organization; GO:0040008 regulation of growth; GO:0043968 histone H2A acetylation; GO:0090316 positive regulation of intracellular protein transport; GO:0006725 cellular aromatic compound metabolic process; GO:0061641 CENP-A containing chromatin organization; GO:1903829 positive regulation of cellular protein localization; GO:0060255 regulation of macromolecule metabolic process; GO:0048285 organelle fission; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0050896 response to stimulus; GO:0016579 protein deubiquitination; GO:0070201 regulation of establishment of protein localization; GO:0071704 organic substance metabolic process; GO:0018205 peptidyl-lysine modification; GO:0006508 proteolysis; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0033157 regulation of intracellular protein transport; GO:0034622 cellular macromolecular complex assembly; GO:0006475 internal protein amino acid acetylation; GO:0006355 regulation of transcription, DNA-templated; GO:0048232 male gamete generation; GO:0051049 regulation of transport; GO:0032388 positive regulation of intracellular transport; GO:0032508 DNA duplex unwinding; GO:0033043 regulation of organelle organization; GO:0006807 nitrogen compound metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:1903214 regulation of protein targeting to mitochondrion; GO:0010556 regulation of macromolecule biosynthetic process; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0007276 gamete generation; GO:0010822 positive regulation of mitochondrion organization; GO:0043933 macromolecular complex subunit organization; GO:0018193 peptidyl-amino acid modification; GO:0032504 multicellular organism reproduction; GO:0006281 DNA repair; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:1903146 regulation of mitophagy; GO:0044703 multi-organism reproductive process; GO:0010467 gene expression; GO:0051128 regulation of cellular component organization; GO:0022402 cell cycle process; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0000812 Swr1 complex; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0097346 INO80-type complex; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0070603 SWI/SNF superfamily-type complex; GO:0043189 H4/H2A histone acetyltransferase complex; GO:0000123 histone acetyltransferase complex; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0035267 NuA4 histone acetyltransferase complex; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0005815 microtubule organizing center; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0031248 protein acetyltransferase complex; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0044454 nuclear chromosome part; GO:0005694 chromosome; GO:1903561 extracellular vesicle; GO:0000790 nuclear chromatin; GO:0071339 MLL1 complex; GO:0043227 membrane-bounded organelle; GO:1902493 acetyltransferase complex; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0033202 DNA helicase complex; GO:0044665 MLL1/2 complex; GO:0043232 intracellular non-membrane-bounded organelle; GO:0031011 Ino80 complex; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0035097 histone methyltransferase complex; GO:1902562 H4 histone acetyltransferase complex; GO:1990234 transferase complex; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0034708 methyltransferase complex; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0000785 chromatin; GO:0016363 nuclear matrix; GO:0000228 nuclear chromosome; GO:0034399 nuclear periphery; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0097255 R2TP complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0008026 ATP-dependent helicase activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0016887 ATPase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0045296 cadherin binding; GO:0004003 ATP-dependent DNA helicase activity; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0043141 ATP-dependent 5'-3' DNA helicase activity; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0008094 DNA-dependent ATPase activity; GO:0003678 DNA helicase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0070035 purine NTP-dependent helicase activity; GO:0005524 ATP binding; GO:0004386 helicase activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0050839 cell adhesion molecule binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0042623 ATPase activity, coupled; GO:0043139 5'-3' DNA helicase activity; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; ","K04499","RUVBL1; RuvB-like protein 1 (pontin 52)","hsa04310 Wnt signaling pathway - Homo sapiens (human); ","IPR003593; IPR010339; IPR027417; ","\"AAA+ ATPase domain; TIP49, C-terminal; P-loop containing nucleoside triphosphate hydrolase; \"\r"]
["Q9Y266","Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC","NUDC",38.242,41.991,37.8,12,15,12,0.975,0.966,0.986,1.06,1.05,1.007,1.065,0.0204,"cytoplasm\r","GO:0032502 developmental process; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0000278 mitotic cell cycle; GO:0007059 chromosome segregation; GO:0007067 mitotic nuclear division; GO:0048285 organelle fission; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0008283 cell proliferation; GO:0032501 multicellular organismal process; GO:1903047 mitotic cell cycle process; GO:0006457 protein folding; GO:1902589 single-organism organelle organization; GO:0000819 sister chromatid segregation; GO:0051276 chromosome organization; GO:0044767 single-organism developmental process; GO:0098813 nuclear chromosome segregation; GO:0006996 organelle organization; GO:0000280 nuclear division; GO:0051301 cell division; GO:0007275 multicellular organism development; GO:0007062 sister chromatid cohesion; GO:0022402 cell cycle process; GO:0048856 anatomical structure development; GO:0009987 cellular process; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0005874 microtubule; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0099080 supramolecular complex; GO:0044422 organelle part; GO:0099081 supramolecular polymer; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005856 cytoskeleton; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0050839 cell adhesion molecule binding; GO:0005515 protein binding; GO:0051082 unfolded protein binding; GO:0005488 binding; GO:0045296 cadherin binding; ",{"$nulls":3},"IPR007052; IPR025934; IPR008978; IPR032572; ","CS domain; NudC N-terminal domain; HSP20-like chaperone; Nuclear migration protein nudC; \r"]
["Q9Y276","Mitochondrial chaperone BCS1 OS=Homo sapiens OX=9606 GN=BCS1L","BCS1L",47.534,20.289,12.4,4,5,4,1.035,1.033,1.002,0.994,0.971,0.977,0.958,0.028,"cyto_nucl\r","GO:0017062 respiratory chain complex III assembly; GO:0044085 cellular component biogenesis; GO:0016043 cellular component organization; GO:0034622 cellular macromolecular complex assembly; GO:0071822 protein complex subunit organization; GO:0017004 cytochrome complex assembly; GO:0008535 respiratory chain complex IV assembly; GO:0010257 NADH dehydrogenase complex assembly; GO:0034551 mitochondrial respiratory chain complex III assembly; GO:0043933 macromolecular complex subunit organization; GO:0032981 mitochondrial respiratory chain complex I assembly; GO:0097031 mitochondrial respiratory chain complex I biogenesis; GO:0097034 mitochondrial respiratory chain complex IV biogenesis; GO:0022607 cellular component assembly; GO:0006996 organelle organization; GO:0065003 macromolecular complex assembly; GO:0007005 mitochondrion organization; GO:0033617 mitochondrial respiratory chain complex IV assembly; GO:0070271 protein complex biogenesis; GO:0009987 cellular process; GO:0097033 mitochondrial respiratory chain complex III biogenesis; GO:0033108 mitochondrial respiratory chain complex assembly; GO:0006461 protein complex assembly; GO:0071840 cellular component organization or biogenesis; GO:0043623 cellular protein complex assembly; ","GO:0016020 membrane; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0098798 mitochondrial protein complex; GO:0005623 cell; GO:0044455 mitochondrial membrane part; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:1902494 catalytic complex; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005750 mitochondrial respiratory chain complex III; GO:0019866 organelle inner membrane; GO:1990351 transporter complex; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0098803 respiratory chain complex; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0070069 cytochrome complex; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:1902495 transmembrane transporter complex; GO:0045275 respiratory chain complex III; GO:0016021 integral component of membrane; GO:0005739 mitochondrion; GO:0005746 mitochondrial respiratory chain; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:1990204 oxidoreductase complex; GO:0031975 envelope; GO:0043234 protein complex; GO:0070469 respiratory chain; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K08900",null,null,"IPR003959; IPR003593; IPR027417; IPR014851; ","\"ATPase, AAA-type, core; AAA+ ATPase domain; P-loop containing nucleoside triphosphate hydrolase; BCS1, N-terminal; \"\r"]
["Q9Y277","Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3","VDAC3",30.658,61.671,34.6,8,12,8,0.978,0.952,0.987,0.992,1.038,1.03,1.049,0.0541,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0060491 regulation of cell projection assembly; GO:0044070 regulation of anion transport; GO:0044699 single-organism process; GO:0031344 regulation of cell projection organization; GO:0044087 regulation of cellular component biogenesis; GO:1902115 regulation of organelle assembly; GO:0051234 establishment of localization; GO:1902578 single-organism localization; GO:0032879 regulation of localization; GO:0044765 single-organism transport; GO:1902017 regulation of cilium assembly; GO:0015851 nucleobase transport; GO:0051049 regulation of transport; GO:0043269 regulation of ion transport; GO:0033043 regulation of organelle organization; GO:0071702 organic substance transport; GO:1903959 regulation of anion transmembrane transport; GO:0034762 regulation of transmembrane transport; GO:0006810 transport; GO:0006820 anion transport; GO:0055085 transmembrane transport; GO:0050789 regulation of biological process; GO:0034765 regulation of ion transmembrane transport; GO:0015853 adenine transport; GO:0006811 ion transport; GO:0006863 purine nucleobase transport; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0071705 nitrogen compound transport; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0019867 outer membrane; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0005740 mitochondrial envelope; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0031968 organelle outer membrane; GO:0043227 membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0044429 mitochondrial part; GO:0046930 pore complex; GO:0005741 mitochondrial outer membrane; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0031975 envelope; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0015075 ion transmembrane transporter activity; GO:0022803 passive transmembrane transporter activity; GO:0005253 anion channel activity; GO:0022892 substrate-specific transporter activity; GO:0000166 nucleotide binding; GO:0015267 channel activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0005244 voltage-gated ion channel activity; GO:0008308 voltage-gated anion channel activity; GO:0022829 wide pore channel activity; GO:0022838 substrate-specific channel activity; GO:0005488 binding; GO:0015288 porin activity; GO:0022836 gated channel activity; GO:0005216 ion channel activity; GO:0022832 voltage-gated channel activity; GO:0008509 anion transmembrane transporter activity; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; GO:0036094 small molecule binding; ","K15041","VDAC3; voltage-dependent anion channel protein 3","hsa04218 Cellular senescence - Homo sapiens (human); hsa04216 Ferroptosis - Homo sapiens (human); hsa04979 Cholesterol metabolism - Homo sapiens (human); hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human); hsa04217 Necroptosis - Homo sapiens (human); hsa04020 Calcium signaling pathway - Homo sapiens (human); hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human); hsa05203 Viral carcinogenesis - Homo sapiens (human); hsa05166 HTLV-I infection - Homo sapiens (human); hsa05016 Huntington's disease - Homo sapiens (human); hsa05161 Hepatitis B - Homo sapiens (human); hsa05012 Parkinson's disease - Homo sapiens (human); ","IPR023614; ","Porin domain; \r"]
["Q9Y279","V-set and immunoglobulin domain-containing protein 4 OS=Homo sapiens OX=9606 GN=VSIG4","VSIG4",43.987,10.913,8.3,3,3,3,0.908,0.966,0.929,1.021,1.112,1.062,1.14,0.0129,"plasma membrane\r","GO:0050794 regulation of cellular process; GO:0050863 regulation of T cell activation; GO:0002694 regulation of leukocyte activation; GO:0050672 negative regulation of lymphocyte proliferation; GO:0032944 regulation of mononuclear cell proliferation; GO:0007162 negative regulation of cell adhesion; GO:0042127 regulation of cell proliferation; GO:0051250 negative regulation of lymphocyte activation; GO:0002252 immune effector process; GO:0042130 negative regulation of T cell proliferation; GO:0022408 negative regulation of cell-cell adhesion; GO:0051241 negative regulation of multicellular organismal process; GO:0006959 humoral immune response; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0051249 regulation of lymphocyte activation; GO:0001818 negative regulation of cytokine production; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:0045087 innate immune response; GO:0008285 negative regulation of cell proliferation; GO:0071704 organic substance metabolic process; GO:0050866 negative regulation of cell activation; GO:0006956 complement activation; GO:0008152 metabolic process; GO:0070664 negative regulation of leukocyte proliferation; GO:1903037 regulation of leukocyte cell-cell adhesion; GO:0070663 regulation of leukocyte proliferation; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0002695 negative regulation of leukocyte activation; GO:0050778 positive regulation of immune response; GO:0002253 activation of immune response; GO:0006950 response to stress; GO:1903038 negative regulation of leukocyte cell-cell adhesion; GO:0032703 negative regulation of interleukin-2 production; GO:0050670 regulation of lymphocyte proliferation; GO:0042129 regulation of T cell proliferation; GO:0032945 negative regulation of mononuclear cell proliferation; GO:0002376 immune system process; GO:0072376 protein activation cascade; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0030155 regulation of cell adhesion; GO:0022407 regulation of cell-cell adhesion; GO:0050776 regulation of immune response; GO:0002683 negative regulation of immune system process; GO:0050865 regulation of cell activation; GO:0050789 regulation of biological process; GO:0006957 complement activation, alternative pathway; GO:0032663 regulation of interleukin-2 production; GO:0002684 positive regulation of immune system process; GO:0048583 regulation of response to stimulus; GO:0001817 regulation of cytokine production; GO:0002682 regulation of immune system process; GO:0006952 defense response; GO:0048584 positive regulation of response to stimulus; GO:0006955 immune response; GO:0050868 negative regulation of T cell activation; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0044425 membrane part; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0031224 intrinsic component of membrane; GO:0043227 membrane-bounded organelle; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:0005515 protein binding; GO:0005488 binding; ","K19822","VSIG4; V-set and immunoglobulin domain-containing protein 4","hsa04610 Complement and coagulation cascades - Homo sapiens (human); ","IPR003598; IPR007110; IPR013783; IPR003599; IPR013106; ","Immunoglobulin subtype 2; Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin subtype; Immunoglobulin V-set domain; \r"]
["Q9Y281","Cofilin-2 OS=Homo sapiens OX=9606 GN=CFL2","CFL2",18.736,6.5737,22.3,4,10,2,1.245,1.21,1.084,0.825,0.837,0.835,0.706,0.0146,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0043243 positive regulation of protein complex disassembly; GO:0048869 cellular developmental process; GO:0032989 cellular component morphogenesis; GO:0044699 single-organism process; GO:0030832 regulation of actin filament length; GO:0043241 protein complex disassembly; GO:0051130 positive regulation of cellular component organization; GO:0030036 actin cytoskeleton organization; GO:0022607 cellular component assembly; GO:0032535 regulation of cellular component size; GO:0030043 actin filament fragmentation; GO:0051493 regulation of cytoskeleton organization; GO:0007519 skeletal muscle tissue development; GO:0032502 developmental process; GO:0031032 actomyosin structure organization; GO:0030836 positive regulation of actin filament depolymerization; GO:0009888 tissue development; GO:0071822 protein complex subunit organization; GO:0060537 muscle tissue development; GO:0044763 single-organism cellular process; GO:0019725 cellular homeostasis; GO:0008154 actin polymerization or depolymerization; GO:0048522 positive regulation of cellular process; GO:0060538 skeletal muscle organ development; GO:0032501 multicellular organismal process; GO:0030042 actin filament depolymerization; GO:1901881 positive regulation of protein depolymerization; GO:1902589 single-organism organelle organization; GO:0048513 animal organ development; GO:0045214 sarcomere organization; GO:0050789 regulation of biological process; GO:0055002 striated muscle cell development; GO:0007517 muscle organ development; GO:0010638 positive regulation of organelle organization; GO:0046716 muscle cell cellular homeostasis; GO:1902905 positive regulation of supramolecular fiber organization; GO:0043244 regulation of protein complex disassembly; GO:0030834 regulation of actin filament depolymerization; GO:0048856 anatomical structure development; GO:0097435 supramolecular fiber organization; GO:1902903 regulation of supramolecular fiber organization; GO:0014706 striated muscle tissue development; GO:0050794 regulation of cellular process; GO:0055001 muscle cell development; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0032956 regulation of actin cytoskeleton organization; GO:0007015 actin filament organization; GO:0060249 anatomical structure homeostasis; GO:0048468 cell development; GO:0042592 homeostatic process; GO:0009653 anatomical structure morphogenesis; GO:0030154 cell differentiation; GO:0070925 organelle assembly; GO:0030239 myofibril assembly; GO:0043624 cellular protein complex disassembly; GO:0061061 muscle structure development; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0051261 protein depolymerization; GO:0051146 striated muscle cell differentiation; GO:0051495 positive regulation of cytoskeleton organization; GO:0048731 system development; GO:1901879 regulation of protein depolymerization; GO:0010927 cellular component assembly involved in morphogenesis; GO:0033043 regulation of organelle organization; GO:0032984 macromolecular complex disassembly; GO:0032970 regulation of actin filament-based process; GO:0048518 positive regulation of biological process; GO:0043933 macromolecular complex subunit organization; GO:0008064 regulation of actin polymerization or depolymerization; GO:0044767 single-organism developmental process; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0042692 muscle cell differentiation; GO:0090066 regulation of anatomical structure size; GO:0022411 cellular component disassembly; GO:0051128 regulation of cellular component organization; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0030016 myofibril; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0030018 Z disc; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0031674 I band; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0005856 cytoskeleton; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043292 contractile fiber; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005576 extracellular region; GO:0015629 actin cytoskeleton; GO:0099081 supramolecular polymer; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0016363 nuclear matrix; GO:0030017 sarcomere; GO:0044449 contractile fiber part; GO:0034399 nuclear periphery; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0051015 actin filament binding; GO:0008092 cytoskeletal protein binding; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0003779 actin binding; GO:0005515 protein binding; GO:0032403 protein complex binding; ","K05765","CFL; cofilin","hsa05133 Pertussis - Homo sapiens (human); hsa04666 Fc gamma R-mediated phagocytosis - Homo sapiens (human); hsa04360 Axon guidance - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); ","IPR029006; IPR002108; ","ADF-H/Gelsolin-like domain; Actin-depolymerising factor homology domain; \r"]
["Q9Y282","Endoplasmic reticulum-Golgi intermediate compartment protein 3 OS=Homo sapiens OX=9606 GN=ERGIC3","ERGIC3",43.222,5.3448,5.7,2,2,2,1,0.986,0.92,1.059,1.059,0.985,1.068,0.136,"plasma membrane\r","GO:0006810 transport; GO:0051179 localization; GO:0016192 vesicle-mediated transport; GO:0051234 establishment of localization; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0098588 bounding membrane of organelle; GO:0031090 organelle membrane; GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044432 endoplasmic reticulum part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005793 endoplasmic reticulum-Golgi intermediate compartment; GO:0005794 Golgi apparatus; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; ",null,"K20367",null,null,"IPR012936; ","\"Endoplasmic reticulum vesicle transporter, C-terminal; \"\r"]
["Q9Y285","Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA","FARSA",57.563,42.465,16.7,8,10,8,0.927,0.943,0.952,1.012,1.065,1.052,1.109,0.00394,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0016043 cellular component organization; GO:0006518 peptide metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0043039 tRNA aminoacylation; GO:0044237 cellular metabolic process; GO:0051259 protein oligomerization; GO:0071704 organic substance metabolic process; GO:0006432 phenylalanyl-tRNA aminoacylation; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0046483 heterocycle metabolic process; GO:0022607 cellular component assembly; GO:0051262 protein tetramerization; GO:0006139 nucleobase-containing compound metabolic process; GO:0051290 protein heterotetramerization; GO:0065003 macromolecular complex assembly; GO:0034641 cellular nitrogen compound metabolic process; GO:0006418 tRNA aminoacylation for protein translation; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0006412 translation; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0071822 protein complex subunit organization; GO:0043043 peptide biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0051291 protein heterooligomerization; GO:0016070 RNA metabolic process; GO:0006399 tRNA metabolic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0090304 nucleic acid metabolic process; GO:0044710 single-organism metabolic process; GO:0043038 amino acid activation; GO:0019752 carboxylic acid metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0070271 protein complex biogenesis; GO:0006082 organic acid metabolic process; GO:0034660 ncRNA metabolic process; GO:0043436 oxoacid metabolic process; GO:0071840 cellular component organization or biogenesis; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:1902494 catalytic complex; GO:0044464 cell part; GO:0005622 intracellular; GO:0009328 phenylalanine-tRNA ligase complex; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds; GO:0003723 RNA binding; GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0016875 ligase activity, forming carbon-oxygen bonds; GO:0016874 ligase activity; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0004826 phenylalanine-tRNA ligase activity; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0000049 tRNA binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0004812 aminoacyl-tRNA ligase activity; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K01889","FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]","hsa00970 Aminoacyl-tRNA biosynthesis - Homo sapiens (human); ","IPR011991; IPR002319; IPR006195; ","\"Winged helix-turn-helix DNA-binding domain; Phenylalanyl-tRNA synthetase; Aminoacyl-tRNA synthetase, class II; \"\r"]
["Q9Y287","Integral membrane protein 2B OS=Homo sapiens OX=9606 GN=ITM2B","ITM2B",30.338,7.9903,12,3,3,3,0.886,0.917,0.979,0.964,1.145,1.102,1.154,0.0771,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0060255 regulation of macromolecule metabolic process; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0031324 negative regulation of cellular metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0009889 regulation of biosynthetic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0007275 multicellular organism development; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0009987 cellular process; GO:1903019 negative regulation of glycoprotein metabolic process; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0048731 system development; GO:0010559 regulation of glycoprotein biosynthetic process; GO:1903018 regulation of glycoprotein metabolic process; GO:0042984 regulation of amyloid precursor protein biosynthetic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:0031323 regulation of cellular metabolic process; GO:0009892 negative regulation of metabolic process; GO:0032501 multicellular organismal process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0009890 negative regulation of biosynthetic process; GO:0050789 regulation of biological process; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0010561 negative regulation of glycoprotein biosynthetic process; GO:0031327 negative regulation of cellular biosynthetic process; GO:0042985 negative regulation of amyloid precursor protein biosynthetic process; GO:0048856 anatomical structure development; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0030660 Golgi-associated vesicle membrane; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0031301 integral component of organelle membrane; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0010008 endosome membrane; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005798 Golgi-associated vesicle; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0031300 intrinsic component of organelle membrane; GO:0044444 cytoplasmic part; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0033218 amide binding; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0001540 beta-amyloid binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0042277 peptide binding; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K18264",null,null,"IPR007084; ","BRICHOS domain; \r"]
["Q9Y291","28S ribosomal protein S33, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS33","MRPS33",12.629,2.5579,8.5,1,2,1,0.811,0.912,0.887,1.204,1.162,1.02,1.297,0.0136,"nucleus\r","GO:0016043 cellular component organization; GO:0006518 peptide metabolic process; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:0043241 protein complex disassembly; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0043624 cellular protein complex disassembly; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006412 translation; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0071822 protein complex subunit organization; GO:0006414 translational elongation; GO:0043043 peptide biosynthetic process; GO:0044763 single-organism cellular process; GO:0032984 macromolecular complex disassembly; GO:0006807 nitrogen compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0032543 mitochondrial translation; GO:0070126 mitochondrial translational termination; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0006415 translational termination; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0070125 mitochondrial translational elongation; GO:0044260 cellular macromolecule metabolic process; GO:0022411 cellular component disassembly; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0071840 cellular component organization or biogenesis; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0015935 small ribosomal subunit; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0000313 organellar ribosome; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044391 ribosomal subunit; GO:0005622 intracellular; GO:0044464 cell part; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005840 ribosome; GO:0005759 mitochondrial matrix; GO:0000314 organellar small ribosomal subunit; GO:0044429 mitochondrial part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005761 mitochondrial ribosome; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005763 mitochondrial small ribosomal subunit; GO:0031975 envelope; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0003735 structural constituent of ribosome; GO:0005198 structural molecule activity; ","K17411"]
["Q9Y295","Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1","DRG1",40.542,21.882,16.6,5,7,5,0.964,0.98,0.887,1.098,1.054,1.067,1.137,0.0176,"cytoplasm\r","GO:0044707 single-multicellular organism process; GO:0006725 cellular aromatic compound metabolic process; GO:0097659 nucleic acid-templated transcription; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0043170 macromolecule metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0032502 developmental process; GO:0018130 heterocycle biosynthetic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0044238 primary metabolic process; GO:0032501 multicellular organismal process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0016070 RNA metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0090304 nucleic acid metabolic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0006351 transcription, DNA-templated; GO:0044767 single-organism developmental process; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0048856 anatomical structure development; GO:1901362 organic cyclic compound biosynthetic process; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0005844 polysome; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0042802 identical protein binding; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0008134 transcription factor binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0036094 small molecule binding; ",{"$nulls":3},"IPR012676; IPR005225; IPR006073; IPR004095; IPR031167; IPR031662; IPR027417; IPR012675; ","\"TGS-like; Small GTP-binding protein domain; GTP binding domain; TGS; OBG-type guanine nucleotide-binding (G) domain; GTP binding protein, second domain; P-loop containing nucleoside triphosphate hydrolase; Beta-grasp domain; \"\r"]
["Q9Y296","Trafficking protein particle complex subunit 4 OS=Homo sapiens OX=9606 GN=TRAPPC4","TRAPPC4",24.34,8.6808,16.4,3,3,3,1.002,0.993,0.943,1.058,1.042,0.97,1.045,0.254,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:0051640 organelle localization; GO:0006901 vesicle coating; GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0048207 vesicle targeting, rough ER to cis-Golgi; GO:0016358 dendrite development; GO:0048208 COPII vesicle coating; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0048193 Golgi vesicle transport; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0006903 vesicle targeting; GO:0048468 cell development; GO:0051234 establishment of localization; GO:0030154 cell differentiation; GO:0051649 establishment of localization in cell; GO:0051345 positive regulation of hydrolase activity; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0044093 positive regulation of molecular function; GO:0048199 vesicle targeting, to, from or within Golgi; GO:0051648 vesicle localization; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0051650 establishment of vesicle localization; GO:0071822 protein complex subunit organization; GO:0043547 positive regulation of GTPase activity; GO:0090114 COPII-coated vesicle budding; GO:0048731 system development; GO:0048699 generation of neurons; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0016050 vesicle organization; GO:0051656 establishment of organelle localization; GO:0031175 neuron projection development; GO:0032501 multicellular organismal process; GO:0043085 positive regulation of catalytic activity; GO:0051641 cellular localization; GO:0043933 macromolecular complex subunit organization; GO:0006810 transport; GO:0030182 neuron differentiation; GO:0051336 regulation of hydrolase activity; GO:0030030 cell projection organization; GO:0050790 regulation of catalytic activity; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0006900 membrane budding; GO:0061024 membrane organization; GO:0043087 regulation of GTPase activity; GO:0065009 regulation of molecular function; GO:0051179 localization; GO:0070271 protein complex biogenesis; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0048856 anatomical structure development; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0030425 dendrite; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070382 exocytic vesicle; GO:0008021 synaptic vesicle; GO:0098793 presynapse; GO:0044464 cell part; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0098791 Golgi subcompartment; GO:0044431 Golgi apparatus part; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0044456 synapse part; GO:0099023 tethering complex; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0042995 cell projection; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0005795 Golgi stack; GO:0005829 cytosol; GO:0045202 synapse; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0036477 somatodendritic compartment; GO:0030008 TRAPP complex; GO:0043234 protein complex; GO:0030133 transport vesicle; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; GO:0031984 organelle subcompartment; ","GO:0005088 Ras guanyl-nucleotide exchange factor activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0017112 Rab guanyl-nucleotide exchange factor activity; GO:0005085 guanyl-nucleotide exchange factor activity; GO:0005488 binding; ","K20303",null,null,"IPR011012; ","Longin-like domain; \r"]
["Q9Y2A7","Nck-associated protein 1 OS=Homo sapiens OX=9606 GN=NCKAP1","NCKAP1",128.79,96.686,19.1,19,27,18,0.968,0.986,0.951,1.068,1.047,0.967,1.061,0.143,"nucleus\r","GO:0044700 single organism signaling; GO:0030833 regulation of actin filament polymerization; GO:0065008 regulation of biological quality; GO:0007166 cell surface receptor signaling pathway; GO:0060491 regulation of cell projection assembly; GO:0038094 Fc-gamma receptor signaling pathway; GO:0044699 single-organism process; GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation; GO:0044764 multi-organism cellular process; GO:0030832 regulation of actin filament length; GO:0051234 establishment of localization; GO:0006909 phagocytosis; GO:0051130 positive regulation of cellular component organization; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0006915 apoptotic process; GO:0032535 regulation of cellular component size; GO:0032271 regulation of protein polymerization; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0051493 regulation of cytoskeleton organization; GO:0044419 interspecies interaction between organisms; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0044765 single-organism transport; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis; GO:0051716 cellular response to stimulus; GO:0031346 positive regulation of cell projection organization; GO:0010591 regulation of lamellipodium assembly; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0048522 positive regulation of cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0007264 small GTPase mediated signal transduction; GO:0002764 immune response-regulating signaling pathway; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0006810 transport; GO:1902745 positive regulation of lamellipodium organization; GO:0050789 regulation of biological process; GO:0043254 regulation of protein complex assembly; GO:0010638 positive regulation of organelle organization; GO:0007417 central nervous system development; GO:0048583 regulation of response to stimulus; GO:0016601 Rac protein signal transduction; GO:0002682 regulation of immune system process; GO:1902905 positive regulation of supramolecular fiber organization; GO:0002431 Fc receptor mediated stimulatory signaling pathway; GO:0048010 vascular endothelial growth factor receptor signaling pathway; GO:0048856 anatomical structure development; GO:0007265 Ras protein signal transduction; GO:1902903 regulation of supramolecular fiber organization; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0002252 immune effector process; GO:0032956 regulation of actin cytoskeleton organization; GO:0031344 regulation of cell projection organization; GO:0044087 regulation of cellular component biogenesis; GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation; GO:0050896 response to stimulus; GO:1902578 single-organism localization; GO:1902743 regulation of lamellipodium organization; GO:0016032 viral process; GO:0002757 immune response-activating signal transduction; GO:0010592 positive regulation of lamellipodium assembly; GO:0007275 multicellular organism development; GO:0038093 Fc receptor signaling pathway; GO:0050778 positive regulation of immune response; GO:0009987 cellular process; GO:0002253 activation of immune response; GO:0051495 positive regulation of cytoskeleton organization; GO:0051125 regulation of actin nucleation; GO:0035556 intracellular signal transduction; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0033043 regulation of organelle organization; GO:0002376 immune system process; GO:0032970 regulation of actin filament-based process; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0008064 regulation of actin polymerization or depolymerization; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0002684 positive regulation of immune system process; GO:0090066 regulation of anatomical structure size; GO:0051128 regulation of cellular component organization; GO:0012501 programmed cell death; GO:0051179 localization; GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis; GO:0048584 positive regulation of response to stimulus; GO:0044089 positive regulation of cellular component biogenesis; GO:0051127 positive regulation of actin nucleation; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0070062 extracellular exosome; GO:0098590 plasma membrane region; GO:0005925 focal adhesion; GO:0031256 leading edge membrane; GO:0044464 cell part; GO:0005622 intracellular; GO:0044425 membrane part; GO:0030027 lamellipodium; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0031252 cell leading edge; GO:0042995 cell projection; GO:0070161 anchoring junction; GO:0044463 cell projection part; GO:0005829 cytosol; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0031209 SCAR complex; GO:0044459 plasma membrane part; GO:0031253 cell projection membrane; GO:0031258 lamellipodium membrane; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; GO:0032403 protein complex binding; GO:0044877 macromolecular complex binding; ","K05750","NCKAP1; NCK-associated protein 1","hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); "]
["Q9Y2B0","Protein canopy homolog 2 OS=Homo sapiens OX=9606 GN=CNPY2","CNPY2",20.652,12.525,19.8,3,4,3,0.926,1.038,0.926,1.07,1.074,0.974,1.079,0.199,"extracellular\r","GO:0044700 single organism signaling; GO:0050794 regulation of cellular process; GO:0007166 cell surface receptor signaling pathway; GO:0010869 regulation of receptor biosynthetic process; GO:0060255 regulation of macromolecule metabolic process; GO:0009891 positive regulation of biosynthetic process; GO:0044699 single-organism process; GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process; GO:0045714 regulation of low-density lipoprotein particle receptor biosynthetic process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0009889 regulation of biosynthetic process; GO:0010984 regulation of lipoprotein particle clearance; GO:0009987 cellular process; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0010870 positive regulation of receptor biosynthetic process; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0010468 regulation of gene expression; GO:0009888 tissue development; GO:0010629 negative regulation of gene expression; GO:0080090 regulation of primary metabolic process; GO:0010988 regulation of low-density lipoprotein particle clearance; GO:0048522 positive regulation of cellular process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0023052 signaling; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0009892 negative regulation of metabolic process; GO:0048518 positive regulation of biological process; GO:0050789 regulation of biological process; GO:0051247 positive regulation of protein metabolic process; GO:0051246 regulation of protein metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0019222 regulation of metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0048856 anatomical structure development; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0043229 intracellular organelle; GO:0031226 intrinsic component of plasma membrane; GO:0005783 endoplasmic reticulum; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR021852; IPR008139; ","Domain of unknown function DUF3456; Saposin B type domain; \r"]
["Q9Y2D0","Carbonic anhydrase 5B, mitochondrial OS=Homo sapiens OX=9606 GN=CA5B","CA5B",36.433,4.9673,6,2,3,2,0.984,1.135,1.068,0.976,0.913,0.943,0.889,0.0627,"mitochondria\r","GO:0006810 transport; GO:0006820 anion transport; GO:0015711 organic anion transport; GO:0008152 metabolic process; GO:0006730 one-carbon metabolic process; GO:0006811 ion transport; GO:0044710 single-organism metabolic process; GO:0044281 small molecule metabolic process; GO:0015701 bicarbonate transport; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0071702 organic substance transport; GO:0051179 localization; GO:0009987 cellular process; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0016829 lyase activity; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0016836 hydro-lyase activity; GO:0008270 zinc ion binding; GO:0004089 carbonate dehydratase activity; GO:0016835 carbon-oxygen lyase activity; ","K01672","CA; carbonic anhydrase [EC:4.2.1.1]","hsa00910 Nitrogen metabolism - Homo sapiens (human); ","IPR001148; ","Alpha carbonic anhydrase; \r"]
["Q9Y2D4","Exocyst complex component 6B OS=Homo sapiens OX=9606 GN=EXOC6B","EXOC6B",94.2,23.348,8.4,6,7,6,1.05,1.013,0.935,0.95,1.038,1.036,1.009,0.852,"cyto_nucl\r","GO:0006904 vesicle docking involved in exocytosis; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0071702 organic substance transport; GO:0048278 vesicle docking; GO:0022406 membrane docking; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:1902578 single-organism localization; GO:0032940 secretion by cell; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0051179 localization; GO:0009987 cellular process; GO:0006887 exocytosis; GO:0044765 single-organism transport; GO:0046903 secretion; ","GO:0005938 cell cortex; GO:0044464 cell part; GO:0044448 cell cortex part; GO:0005622 intracellular; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0099568 cytoplasmic region; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0000145 exocyst; GO:0043234 protein complex; GO:0005623 cell; GO:0044444 cytoplasmic part; GO:0099023 tethering complex; ","GO:0005515 protein binding; GO:0005488 binding; ","K19985"]
["Q9Y2D5","A-kinase anchor protein 2 OS=Homo sapiens OX=9606 GN=AKAP2","AKAP2",94.659,19.484,5.1,3,3,3,0.881,1.037,0.965,0.993,1.171,0.956,1.082,0.379,"nucleus\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0051716 cellular response to stimulus; GO:0016043 cellular component organization; GO:0007166 cell surface receptor signaling pathway; GO:0044763 single-organism cellular process; GO:0007015 actin filament organization; GO:0044699 single-organism process; GO:0023052 signaling; GO:0050896 response to stimulus; GO:1902589 single-organism organelle organization; GO:0007165 signal transduction; GO:0030036 actin cytoskeleton organization; GO:0050789 regulation of biological process; GO:0007154 cell communication; GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0007010 cytoskeleton organization; GO:0033036 macromolecule localization; GO:0051179 localization; GO:0008104 protein localization; GO:0009987 cellular process; GO:0097435 supramolecular fiber organization; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ",null,"GO:0051018 protein kinase A binding; GO:0005515 protein binding; GO:0005488 binding; ","K16519",null,null,"IPR029304; ","\"A-kinase anchor protein 2, C-terminal domain; \"\r"]
["Q9Y2G3","Probable phospholipid-transporting ATPase IF OS=Homo sapiens OX=9606 GN=ATP11B","ATP11B",134.19,2.7827,0.9,1,1,1,0.941,1.093,1.157,0.909,0.847,1.064,0.884,0.245,"plasma membrane\r","GO:0016043 cellular component organization; GO:0065008 regulation of biological quality; GO:0045321 leukocyte activation; GO:0002283 neutrophil activation involved in immune response; GO:0034220 ion transmembrane transport; GO:0002252 immune effector process; GO:0044699 single-organism process; GO:0045332 phospholipid translocation; GO:0097035 regulation of membrane lipid distribution; GO:0050896 response to stimulus; GO:0051234 establishment of localization; GO:0015917 aminophospholipid transport; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0036230 granulocyte activation; GO:0033036 macromolecule localization; GO:0009987 cellular process; GO:0002274 myeloid leukocyte activation; GO:0046903 secretion; GO:0044765 single-organism transport; GO:0002443 leukocyte mediated immunity; GO:0006869 lipid transport; GO:0002446 neutrophil mediated immunity; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0044802 single-organism membrane organization; GO:0002376 immune system process; GO:0010876 lipid localization; GO:0071702 organic substance transport; GO:0015914 phospholipid transport; GO:0043312 neutrophil degranulation; GO:0002263 cell activation involved in immune response; GO:0002444 myeloid leukocyte mediated immunity; GO:0002366 leukocyte activation involved in immune response; GO:0006810 transport; GO:0006820 anion transport; GO:0055085 transmembrane transport; GO:0015748 organophosphate ester transport; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:0015711 organic anion transport; GO:0032940 secretion by cell; GO:0006811 ion transport; GO:0061024 membrane organization; GO:0001775 cell activation; GO:0043299 leukocyte degranulation; GO:0006955 immune response; GO:0051179 localization; GO:0034204 lipid translocation; GO:0071705 nitrogen compound transport; GO:0006887 exocytosis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0031224 intrinsic component of membrane; GO:0055038 recycling endosome membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005769 early endosome; GO:0055037 recycling endosome; GO:0005765 lysosomal membrane; GO:0031965 nuclear membrane; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:0019866 organelle inner membrane; GO:0005768 endosome; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0005637 nuclear inner membrane; GO:0000323 lytic vacuole; GO:0010008 endosome membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0005635 nuclear envelope; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0035577 azurophil granule membrane; GO:0044440 endosomal part; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0042582 azurophil granule; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0030667 secretory granule membrane; GO:0005766 primary lysosome; GO:0031975 envelope; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0005319 lipid transporter activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0016887 ATPase activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0043492 ATPase activity, coupled to movement of substances; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005548 phospholipid transporter activity; GO:0005215 transporter activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0000287 magnesium ion binding; GO:0005524 ATP binding; GO:0015075 ion transmembrane transporter activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0042623 ATPase activity, coupled; GO:0046872 metal ion binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0004012 phospholipid-translocating ATPase activity; GO:0036094 small molecule binding; GO:0022857 transmembrane transporter activity; ","K01530",null,null,"IPR032630; IPR023299; IPR008250; IPR023214; IPR032631; ","\"P-type ATPase, C-terminal; P-type ATPase, cytoplasmic domain N; P-type ATPase, A  domain; HAD-like domain; P-type ATPase, N-terminal; \"\r"]
["Q9Y2G5","GDP-fucose protein O-fucosyltransferase 2 OS=Homo sapiens OX=9606 GN=POFUT2","POFUT2",49.975,5.5002,4.4,2,2,2,1.036,1.117,1.074,0.878,0.95,0.961,0.864,0.015,"extracellular\r","GO:0043413 macromolecule glycosylation; GO:0010717 regulation of epithelial to mesenchymal transition; GO:0036065 fucosylation; GO:0051046 regulation of secretion; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0048729 tissue morphogenesis; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0032879 regulation of localization; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009790 embryo development; GO:0048598 embryonic morphogenesis; GO:0032502 developmental process; GO:0010468 regulation of gene expression; GO:0006486 protein glycosylation; GO:0009101 glycoprotein biosynthetic process; GO:0009888 tissue development; GO:0001704 formation of primary germ layer; GO:0044281 small molecule metabolic process; GO:0001707 mesoderm formation; GO:0044763 single-organism cellular process; GO:0009100 glycoprotein metabolic process; GO:0005975 carbohydrate metabolic process; GO:0006004 fucose metabolic process; GO:0032501 multicellular organismal process; GO:0007498 mesoderm development; GO:0044723 single-organism carbohydrate metabolic process; GO:0050789 regulation of biological process; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006464 cellular protein modification process; GO:0006493 protein O-linked glycosylation; GO:0036211 protein modification process; GO:0036066 protein O-linked fucosylation; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0060255 regulation of macromolecule metabolic process; GO:0044267 cellular protein metabolic process; GO:0051239 regulation of multicellular organismal process; GO:0071704 organic substance metabolic process; GO:0007369 gastrulation; GO:0009653 anatomical structure morphogenesis; GO:0005996 monosaccharide metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0007275 multicellular organism development; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0070085 glycosylation; GO:0045595 regulation of cell differentiation; GO:0051049 regulation of transport; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0048332 mesoderm morphogenesis; GO:0044767 single-organism developmental process; GO:0043412 macromolecule modification; GO:0050793 regulation of developmental process; GO:0019318 hexose metabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0043229 intracellular organelle; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044432 endoplasmic reticulum part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0005794 Golgi apparatus; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; ","GO:0008417 fucosyltransferase activity; GO:0016757 transferase activity, transferring glycosyl groups; GO:0016758 transferase activity, transferring hexosyl groups; GO:0046922 peptide-O-fucosyltransferase activity; GO:0003824 catalytic activity; GO:0016740 transferase activity; ","K03691","POFUT; peptide-O-fucosyltransferase [EC:2.4.1.221]","hsa00514 Other types of O-glycan biosynthesis - Homo sapiens (human); "]
["Q9Y2H0","Disks large-associated protein 4 OS=Homo sapiens OX=9606 GN=DLGAP4","DLGAP4",108.01,4.3199,1.9,2,2,2,0.92,1.049,1.046,0.978,1.084,0.931,0.993,0.91,"nucleus\r","GO:0023052 signaling; ","GO:0016020 membrane; GO:0005623 cell; GO:0044464 cell part; GO:0071944 cell periphery; GO:0005886 plasma membrane; GO:0045202 synapse; ","GO:0005515 protein binding; GO:0005488 binding; "]
["Q9Y2H1","Serine/threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L","STK38L",54.002,5.334,7.1,4,5,2,1.003,0.969,0.918,0.982,1.097,1.034,1.077,0.146,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0016310 phosphorylation; GO:0018209 peptidyl-serine modification; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0006468 protein phosphorylation; GO:0007154 cell communication; GO:0018105 peptidyl-serine phosphorylation; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009987 cellular process; GO:0051716 cellular response to stimulus; GO:0035556 intracellular signal transduction; GO:0023052 signaling; GO:0044238 primary metabolic process; GO:0018193 peptidyl-amino acid modification; GO:0050789 regulation of biological process; GO:0006793 phosphorus metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0051128 regulation of cellular component organization; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:0065007 biological regulation; ","GO:0043226 organelle; GO:0005856 cytoskeleton; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0015629 actin cytoskeleton; GO:0044444 cytoplasmic part; GO:0043228 non-membrane-bounded organelle; ","GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0005515 protein binding; GO:0004672 protein kinase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0008092 cytoskeletal protein binding; GO:0016301 kinase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0000287 magnesium ion binding; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003779 actin binding; GO:0046872 metal ion binding; GO:0004674 protein serine/threonine kinase activity; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K08790",null,null,"IPR000719; IPR017892; IPR011009; IPR000961; ","\"Protein kinase domain; Protein kinase, C-terminal; Protein kinase-like domain; AGC-kinase, C-terminal; \"\r"]
["Q9Y2I8","WD repeat-containing protein 37 OS=Homo sapiens OX=9606 GN=WDR37","WDR37",54.665,6.2223,3.8,2,4,2,0.929,0.925,1.13,0.964,0.99,1.061,1.01,0.856,"nucleus\r","GO:0016072 rRNA metabolic process; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0006725 cellular aromatic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0042254 ribosome biogenesis; GO:1901360 organic cyclic compound metabolic process; GO:0000460 maturation of 5.8S rRNA; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0042273 ribosomal large subunit biogenesis; GO:0071704 organic substance metabolic process; GO:0016070 RNA metabolic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0090304 nucleic acid metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0006364 rRNA processing; GO:0000470 maturation of LSU-rRNA; GO:0044260 cellular macromolecule metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0010467 gene expression; GO:0043170 macromolecule metabolic process; GO:0009987 cellular process; GO:0034660 ncRNA metabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0044452 nucleolar part; GO:0005730 nucleolus; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0030684 preribosome; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0030686 90S preribosome; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0030687 preribosome, large subunit precursor; GO:0070545 PeBoW complex; GO:1990904 ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0043234 protein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR017986; IPR015943; ","WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain; \r"]
["Q9Y2J2","Band 4.1-like protein 3 OS=Homo sapiens OX=9606 GN=EPB41L3","EPB41L3",120.68,24.992,12.7,12,15,8,1.053,1.06,1.064,0.905,1.01,0.951,0.902,0.0825,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0010256 endomembrane system organization; GO:0065008 regulation of biological quality; GO:0007272 ensheathment of neurons; GO:0048869 cellular developmental process; GO:0048666 neuron development; GO:0045216 cell-cell junction organization; GO:0032989 cellular component morphogenesis; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0001558 regulation of cell growth; GO:0030036 actin cytoskeleton organization; GO:0022607 cellular component assembly; GO:0032990 cell part morphogenesis; GO:0008360 regulation of cell shape; GO:0006915 apoptotic process; GO:0048858 cell projection morphogenesis; GO:0051651 maintenance of location in cell; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0043217 myelin maintenance; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0031032 actomyosin structure organization; GO:0032507 maintenance of protein location in cell; GO:0072657 protein localization to membrane; GO:0030866 cortical actin cytoskeleton organization; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0048812 neuron projection morphogenesis; GO:0007009 plasma membrane organization; GO:0032501 multicellular organismal process; GO:0000902 cell morphogenesis; GO:0042552 myelination; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0030030 cell projection organization; GO:0048856 anatomical structure development; GO:0030913 paranodal junction assembly; GO:0050794 regulation of cellular process; GO:0034329 cell junction assembly; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0040008 regulation of growth; GO:0007016 cytoskeletal anchoring at plasma membrane; GO:0008366 axon ensheathment; GO:0030865 cortical cytoskeleton organization; GO:1990778 protein localization to cell periphery; GO:0048468 cell development; GO:0009653 anatomical structure morphogenesis; GO:0030154 cell differentiation; GO:1902578 single-organism localization; GO:0071205 protein localization to juxtaparanode region of axon; GO:0032288 myelin assembly; GO:0002175 protein localization to paranode region of axon; GO:1902580 single-organism cellular localization; GO:0051235 maintenance of location; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0034613 cellular protein localization; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0009987 cellular process; GO:0007043 cell-cell junction assembly; GO:0045185 maintenance of protein location; GO:0048731 system development; GO:0010927 cellular component assembly involved in morphogenesis; GO:0044802 single-organism membrane organization; GO:0031175 neuron projection development; GO:0099612 protein localization to axon; GO:0051641 cellular localization; GO:0030182 neuron differentiation; GO:0072659 protein localization to plasma membrane; GO:0070727 cellular macromolecule localization; GO:0034330 cell junction organization; GO:0008219 cell death; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0061024 membrane organization; GO:0030029 actin filament-based process; GO:0051128 regulation of cellular component organization; GO:0012501 programmed cell death; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0022604 regulation of cell morphogenesis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0019898 extrinsic component of membrane; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005911 cell-cell junction; GO:0005623 cell; GO:0032279 asymmetric synapse; GO:0032589 neuron projection membrane; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0098590 plasma membrane region; GO:0031256 leading edge membrane; GO:0044304 main axon; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0030673 axolemma; GO:0014069 postsynaptic density; GO:0043005 neuron projection; GO:0033270 paranode region of axon; GO:0097458 neuron part; GO:0098984 neuron to neuron synapse; GO:0044456 synapse part; GO:0043229 intracellular organelle; GO:0031252 cell leading edge; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0044224 juxtaparanode region of axon; GO:0033267 axon part; GO:0045202 synapse; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0030424 axon; GO:0044459 plasma membrane part; GO:0098794 postsynapse; GO:0031253 cell projection membrane; GO:0099572 postsynaptic specialization; GO:0044444 cytoplasmic part; ","GO:0003779 actin binding; GO:0005515 protein binding; GO:0008092 cytoskeletal protein binding; GO:0005200 structural constituent of cytoskeleton; GO:0005198 structural molecule activity; GO:0005488 binding; ","K06107",null,null,"IPR019748; IPR018980; IPR018979; IPR019749; IPR008379; IPR011993; IPR029071; IPR007477; IPR014847; IPR000299; IPR014352; ","\"FERM central domain; FERM, C-terminal PH-like domain; FERM, N-terminal; Band 4.1 domain; Band 4.1, C-terminal; PH domain-like; Ubiquitin-related domain; SAB domain; FERM adjacent (FA); FERM domain; FERM/acyl-CoA-binding protein, 3-helical bundle; \"\r"]
["Q9Y2L1","Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3","DIS3",109,26.047,7.6,6,7,6,1.03,0.953,0.999,1.067,0.994,0.968,1.016,0.699,"cyto_nucl\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0065008 regulation of biological quality; GO:0010608 posttranscriptional regulation of gene expression; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0016075 rRNA catabolic process; GO:0071034 CUT catabolic process; GO:0006364 rRNA processing; GO:0044093 positive regulation of molecular function; GO:1901361 organic cyclic compound catabolic process; GO:0043170 macromolecule metabolic process; GO:0071043 CUT metabolic process; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0016072 rRNA metabolic process; GO:0010468 regulation of gene expression; GO:0042254 ribosome biogenesis; GO:1901360 organic cyclic compound metabolic process; GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic; GO:0010605 negative regulation of macromolecule metabolic process; GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; GO:0006401 RNA catabolic process; GO:0016070 RNA metabolic process; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0034661 ncRNA catabolic process; GO:0050789 regulation of biological process; GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; GO:0051336 regulation of hydrolase activity; GO:0090304 nucleic acid metabolic process; GO:0050790 regulation of catalytic activity; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0090305 nucleic acid phosphodiester bond hydrolysis; GO:0016071 mRNA metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic; GO:0048519 negative regulation of biological process; GO:0071704 organic substance metabolic process; GO:0043487 regulation of RNA stability; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0051345 positive regulation of hydrolase activity; GO:0006139 nucleobase-containing compound metabolic process; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0043547 positive regulation of GTPase activity; GO:0010629 negative regulation of gene expression; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:0043488 regulation of mRNA stability; GO:0009892 negative regulation of metabolic process; GO:0043085 positive regulation of catalytic activity; GO:0090501 RNA phosphodiester bond hydrolysis; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0009056 catabolic process; GO:0034660 ncRNA metabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:0046700 heterocycle catabolic process; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0000176 nuclear exosome (RNase complex); GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:1905354 exoribonuclease complex; GO:0043226 organelle; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:1902494 catalytic complex; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; GO:0000178 exosome (RNase complex); ","GO:0003723 RNA binding; GO:0005085 guanyl-nucleotide exchange factor activity; GO:0000175 3'-5'-exoribonuclease activity; GO:0016896 exoribonuclease activity, producing 5'-phosphomonoesters; GO:0008408 3'-5' exonuclease activity; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0098772 molecular function regulator; GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0004532 exoribonuclease activity; GO:0003676 nucleic acid binding; GO:0004518 nuclease activity; GO:0016788 hydrolase activity, acting on ester bonds; GO:0004527 exonuclease activity; GO:0004519 endonuclease activity; GO:0004540 ribonuclease activity; ","K12585","DIS3; exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-]","hsa03018 RNA degradation - Homo sapiens (human); ","IPR033770; IPR012340; IPR002716; IPR033771; IPR029060; ","\"Exosome complex exonuclease RRP44, S1 domain; Nucleic acid-binding, OB-fold; PIN domain; Rrp44-like cold shock domain; PIN domain-like; \"\r"]
["Q9Y2L5","Trafficking protein particle complex subunit 8 OS=Homo sapiens OX=9606 GN=TRAPPC8","TRAPPC8",161,8.8376,2.9,5,5,5,0.997,0.914,1.043,1.032,0.992,1.035,1.036,0.428,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0046907 intracellular transport; GO:1905037 autophagosome organization; GO:0016043 cellular component organization; GO:0048193 Golgi vesicle transport; GO:0006914 autophagy; GO:0044804 nucleophagy; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0022607 cellular component assembly; GO:0070925 organelle assembly; GO:0051345 positive regulation of hydrolase activity; GO:0044093 positive regulation of molecular function; GO:0044248 cellular catabolic process; GO:0007033 vacuole organization; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0016236 macroautophagy; GO:0043547 positive regulation of GTPase activity; GO:0016192 vesicle-mediated transport; GO:0043085 positive regulation of catalytic activity; GO:0051641 cellular localization; GO:0006810 transport; GO:0070727 cellular macromolecule localization; GO:0051336 regulation of hydrolase activity; GO:0030242 pexophagy; GO:0050790 regulation of catalytic activity; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0065009 regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0034497 protein localization to pre-autophagosomal structure; GO:0051179 localization; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0009056 catabolic process; GO:0000045 autophagosome assembly; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0031410 cytoplasmic vesicle; GO:1990072 TRAPPIII protein complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0030008 TRAPP complex; GO:0044431 Golgi apparatus part; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0005794 Golgi apparatus; GO:0000407 pre-autophagosomal structure; GO:0044444 cytoplasmic part; GO:0099023 tethering complex; ","GO:0005088 Ras guanyl-nucleotide exchange factor activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0017112 Rab guanyl-nucleotide exchange factor activity; GO:0005085 guanyl-nucleotide exchange factor activity; GO:0005488 binding; ","K20305",null,null,"IPR011990; ","Tetratricopeptide-like helical domain; \r"]
["Q9Y2Q3","Glutathione S-transferase kappa 1 OS=Homo sapiens OX=9606 GN=GSTK1","GSTK1",25.497,59.166,35.4,7,21,7,1.02,1.028,1.057,0.995,0.977,0.973,0.948,0.0146,"cytoplasm\r","GO:0006518 peptide metabolic process; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0050896 response to stimulus; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:0044272 sulfur compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:1901685 glutathione derivative metabolic process; GO:0008152 metabolic process; GO:1990748 cellular detoxification; GO:0006575 cellular modified amino acid metabolic process; GO:0006749 glutathione metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0098869 cellular oxidant detoxification; GO:0009987 cellular process; GO:0006790 sulfur compound metabolic process; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0009888 tissue development; GO:0044711 single-organism biosynthetic process; GO:0055114 oxidation-reduction process; GO:0009636 response to toxic substance; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:0043603 cellular amide metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:1901687 glutathione derivative biosynthetic process; GO:0042221 response to chemical; GO:0044767 single-organism developmental process; GO:0044710 single-organism metabolic process; GO:0048856 anatomical structure development; GO:0098754 detoxification; GO:0030855 epithelial cell differentiation; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0042579 microbody; GO:0019866 organelle inner membrane; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005759 mitochondrial matrix; GO:0044429 mitochondrial part; GO:0005777 peroxisome; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031975 envelope; GO:0031966 mitochondrial membrane; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0004364 glutathione transferase activity; GO:0015035 protein disulfide oxidoreductase activity; GO:0015036 disulfide oxidoreductase activity; GO:0004602 glutathione peroxidase activity; GO:0005102 receptor binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups; GO:0016667 oxidoreductase activity, acting on a sulfur group of donors; GO:0016209 antioxidant activity; GO:0005515 protein binding; GO:0004601 peroxidase activity; GO:0016740 transferase activity; GO:0016491 oxidoreductase activity; GO:0016684 oxidoreductase activity, acting on peroxide as acceptor; ","K13299","GSTK1; glutathione S-transferase kappa 1 [EC:2.5.1.18]","hsa00480 Glutathione metabolism - Homo sapiens (human); hsa00982 Drug metabolism - cytochrome P450 - Homo sapiens (human); hsa05204 Chemical carcinogenesis - Homo sapiens (human); hsa00980 Metabolism of xenobiotics by cytochrome P450 - Homo sapiens (human); hsa04146 Peroxisome - Homo sapiens (human); ","IPR001853; IPR012336; ","DSBA-like thioredoxin domain; Thioredoxin-like fold; \r"]
["Q9Y2Q5","Ragulator complex protein LAMTOR2 OS=Homo sapiens OX=9606 GN=LAMTOR2","LAMTOR2",13.507,8.6011,38.4,4,5,4,1.004,0.903,1.07,0.983,0.953,1.088,1.016,0.808,"mitochondria\r","GO:0044700 single organism signaling; GO:0032270 positive regulation of cellular protein metabolic process; GO:0045321 leukocyte activation; GO:0006914 autophagy; GO:0044237 cellular metabolic process; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0008152 metabolic process; GO:0044093 positive regulation of molecular function; GO:0009719 response to endogenous stimulus; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0051347 positive regulation of transferase activity; GO:0008104 protein localization; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0002443 leukocyte mediated immunity; GO:0080090 regulation of primary metabolic process; GO:0016049 cell growth; GO:0044763 single-organism cellular process; GO:0031323 regulation of cellular metabolic process; GO:0006810 transport; GO:0000165 MAPK cascade; GO:0010243 response to organonitrogen compound; GO:0051336 regulation of hydrolase activity; GO:0044710 single-organism metabolic process; GO:0050790 regulation of catalytic activity; GO:0071230 cellular response to amino acid stimulus; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0050794 regulation of cellular process; GO:0016310 phosphorylation; GO:0002283 neutrophil activation involved in immune response; GO:0031399 regulation of protein modification process; GO:1901700 response to oxygen-containing compound; GO:0044267 cellular protein metabolic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0032147 activation of protein kinase activity; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0071229 cellular response to acid chemical; GO:0051345 positive regulation of hydrolase activity; GO:0051338 regulation of transferase activity; GO:0044248 cellular catabolic process; GO:0034613 cellular protein localization; GO:0009966 regulation of signal transduction; GO:0023014 signal transduction by protein phosphorylation; GO:1902531 regulation of intracellular signal transduction; GO:0043547 positive regulation of GTPase activity; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0002263 cell activation involved in immune response; GO:0045055 regulated exocytosis; GO:0051247 positive regulation of protein metabolic process; GO:0006793 phosphorus metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0001775 cell activation; GO:0043412 macromolecule modification; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:0006955 immune response; GO:0040007 growth; GO:0006887 exocytosis; GO:0001101 response to acid chemical; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0000186 activation of MAPKK activity; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0033036 macromolecule localization; GO:0033674 positive regulation of kinase activity; GO:0051726 regulation of cell cycle; GO:0070887 cellular response to chemical stimulus; GO:0016236 macroautophagy; GO:0002274 myeloid leukocyte activation; GO:0043200 response to amino acid; GO:0045937 positive regulation of phosphate metabolic process; GO:0002446 neutrophil mediated immunity; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0002444 myeloid leukocyte mediated immunity; GO:0071417 cellular response to organonitrogen compound; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:1901699 cellular response to nitrogen compound; GO:0032940 secretion by cell; GO:0043087 regulation of GTPase activity; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0043299 leukocyte degranulation; GO:0019220 regulation of phosphate metabolic process; GO:0036211 protein modification process; GO:0043549 regulation of kinase activity; GO:0045859 regulation of protein kinase activity; GO:0045786 negative regulation of cell cycle; GO:0002252 immune effector process; GO:0043405 regulation of MAP kinase activity; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0032006 regulation of TOR signaling; GO:0006468 protein phosphorylation; GO:0043408 regulation of MAPK cascade; GO:0023056 positive regulation of signaling; GO:0036230 granulocyte activation; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:0035556 intracellular signal transduction; GO:0032008 positive regulation of TOR signaling; GO:0007050 cell cycle arrest; GO:0001932 regulation of protein phosphorylation; GO:0031401 positive regulation of protein modification process; GO:0043312 neutrophil degranulation; GO:0001934 positive regulation of protein phosphorylation; GO:0045860 positive regulation of protein kinase activity; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0043085 positive regulation of catalytic activity; GO:0002366 leukocyte activation involved in immune response; GO:0070727 cellular macromolecule localization; GO:0042119 neutrophil activation; GO:1901701 cellular response to oxygen-containing compound; GO:0071495 cellular response to endogenous stimulus; GO:0051246 regulation of protein metabolic process; GO:0022402 cell cycle process; GO:0009967 positive regulation of signal transduction; GO:0043410 positive regulation of MAPK cascade; GO:0009056 catabolic process; GO:0007049 cell cycle; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0098857 membrane microdomain; GO:0071986 Ragulator complex; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070821 tertiary granule membrane; GO:0005765 lysosomal membrane; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0031902 late endosome membrane; GO:0005622 intracellular; GO:0044464 cell part; GO:0005764 lysosome; GO:0099503 secretory vesicle; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0098589 membrane region; GO:0005768 endosome; GO:0030141 secretory granule; GO:0045121 membrane raft; GO:0043227 membrane-bounded organelle; GO:0035579 specific granule membrane; GO:0000323 lytic vacuole; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0010008 endosome membrane; GO:0098588 bounding membrane of organelle; GO:0005770 late endosome; GO:0070820 tertiary granule; GO:0044446 intracellular organelle part; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0098852 lytic vacuole membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0030667 secretory granule membrane; GO:0042581 specific granule; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ","K20398","LAMTOR2; ragulator complex protein LAMTOR2","hsa04150 mTOR signaling pathway - Homo sapiens (human); ","IPR004942; ","Roadblock/LAMTOR2 domain; \r"]
["Q9Y2R0","Cytochrome c oxidase assembly factor 3 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=COA3","COA3",11.731,5.784,17.9,2,2,2,0.979,1.033,1.015,0.981,1.042,0.959,0.985,0.629,"plasma membrane\r","GO:0050794 regulation of cellular process; GO:0044085 cellular component biogenesis; GO:0016043 cellular component organization; GO:0032270 positive regulation of cellular protein metabolic process; GO:0017004 cytochrome complex assembly; GO:0060255 regulation of macromolecule metabolic process; GO:0010608 posttranscriptional regulation of gene expression; GO:0009891 positive regulation of biosynthetic process; GO:0009893 positive regulation of metabolic process; GO:0097034 mitochondrial respiratory chain complex IV biogenesis; GO:0022607 cellular component assembly; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0065003 macromolecular complex assembly; GO:0007005 mitochondrion organization; GO:0070129 regulation of mitochondrial translation; GO:0051171 regulation of nitrogen compound metabolic process; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0043623 cellular protein complex assembly; GO:0034622 cellular macromolecular complex assembly; GO:0010468 regulation of gene expression; GO:0071822 protein complex subunit organization; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0045727 positive regulation of translation; GO:0008535 respiratory chain complex IV assembly; GO:0048522 positive regulation of cellular process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0070131 positive regulation of mitochondrial translation; GO:0048518 positive regulation of biological process; GO:0034248 regulation of cellular amide metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0051247 positive regulation of protein metabolic process; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0006417 regulation of translation; GO:0051246 regulation of protein metabolic process; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0033617 mitochondrial respiratory chain complex IV assembly; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0034250 positive regulation of cellular amide metabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0070271 protein complex biogenesis; GO:0033108 mitochondrial respiratory chain complex assembly; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0031305 integral component of mitochondrial inner membrane; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0031304 intrinsic component of mitochondrial inner membrane; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0031301 integral component of organelle membrane; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0043229 intracellular organelle; GO:0098573 intrinsic component of mitochondrial membrane; GO:0044429 mitochondrial part; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0016021 integral component of membrane; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031975 envelope; GO:0032592 integral component of mitochondrial membrane; GO:0031966 mitochondrial membrane; GO:0031300 intrinsic component of organelle membrane; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ","K18175","CCDC56; cytochrome c oxidase assembly factor 3, animal type","hsa04714 Thermogenesis - Homo sapiens (human); "]
["Q9Y2R9","28S ribosomal protein S7, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS7","MRPS7",28.134,21.471,21.1,4,4,4,1.086,1.037,0.93,0.942,1.024,0.994,0.97,0.602,"mitochondria\r","GO:0016043 cellular component organization; GO:0006518 peptide metabolic process; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:0043241 protein complex disassembly; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0043624 cellular protein complex disassembly; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006412 translation; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0071822 protein complex subunit organization; GO:0006414 translational elongation; GO:0043043 peptide biosynthetic process; GO:0044763 single-organism cellular process; GO:0032984 macromolecular complex disassembly; GO:0006807 nitrogen compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0032543 mitochondrial translation; GO:0070126 mitochondrial translational termination; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0006415 translational termination; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0070125 mitochondrial translational elongation; GO:0044260 cellular macromolecule metabolic process; GO:0022411 cellular component disassembly; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0071840 cellular component organization or biogenesis; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0015935 small ribosomal subunit; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0000313 organellar ribosome; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044391 ribosomal subunit; GO:0005622 intracellular; GO:0044464 cell part; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005840 ribosome; GO:0005759 mitochondrial matrix; GO:0000314 organellar small ribosomal subunit; GO:0044429 mitochondrial part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005761 mitochondrial ribosome; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005763 mitochondrial small ribosomal subunit; GO:0031975 envelope; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005198 structural molecule activity; GO:0003735 structural constituent of ribosome; ","K02992","RP-S7; small subunit ribosomal protein S7","hsa03010 Ribosome - Homo sapiens (human); ","IPR023798; ","Ribosomal protein S7 domain; \r"]
["Q9Y2S2","Lambda-crystallin homolog OS=Homo sapiens OX=9606 GN=CRYL1","CRYL1",35.419,25.234,11,3,6,3,1.048,1.165,0.991,1.064,0.874,0.884,0.881,0.18,"extracellular\r","GO:0019640 glucuronate catabolic process to xylulose 5-phosphate; GO:0046365 monosaccharide catabolic process; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0006063 uronic acid metabolic process; GO:0071704 organic substance metabolic process; GO:0051167 xylulose 5-phosphate metabolic process; GO:0008152 metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0005996 monosaccharide metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0044248 cellular catabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:0009987 cellular process; GO:0006629 lipid metabolic process; GO:0044724 single-organism carbohydrate catabolic process; GO:0044711 single-organism biosynthetic process; GO:0055114 oxidation-reduction process; GO:0044712 single-organism catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0072329 monocarboxylic acid catabolic process; GO:1901159 xylulose 5-phosphate biosynthetic process; GO:0044282 small molecule catabolic process; GO:0006631 fatty acid metabolic process; GO:0044238 primary metabolic process; GO:0005975 carbohydrate metabolic process; GO:1901576 organic substance biosynthetic process; GO:0016052 carbohydrate catabolic process; GO:0090407 organophosphate biosynthetic process; GO:0046395 carboxylic acid catabolic process; GO:1901575 organic substance catabolic process; GO:0044723 single-organism carbohydrate metabolic process; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0019585 glucuronate metabolic process; GO:0016054 organic acid catabolic process; GO:0019752 carboxylic acid metabolic process; GO:0019637 organophosphate metabolic process; GO:0006064 glucuronate catabolic process; GO:0006082 organic acid metabolic process; GO:0009056 catabolic process; GO:0043436 oxoacid metabolic process; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0043167 ion binding; GO:0046983 protein dimerization activity; GO:0070403 NAD+ binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0048037 cofactor binding; GO:0016491 oxidoreductase activity; GO:0016614 oxidoreductase activity, acting on CH-OH group of donors; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0051287 NAD binding; GO:0005488 binding; GO:0042803 protein homodimerization activity; GO:0050104 L-gulonate 3-dehydrogenase activity; GO:0043168 anion binding; GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity; GO:0036094 small molecule binding; GO:0050662 coenzyme binding; ","K13247","CRYL1; L-gulonate 3-dehydrogenase [EC:1.1.1.45]","hsa00040 Pentose and glucuronate interconversions - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); ","IPR013328; IPR008927; IPR016040; IPR006176; IPR006108; ","\"6-phosphogluconate dehydrogenase, domain 2; 6-phosphogluconate dehydrogenase C-terminal domain-like; NAD(P)-binding domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding; 3-hydroxyacyl-CoA dehydrogenase, C-terminal; \"\r"]
["Q9Y2T2","AP-3 complex subunit mu-1 OS=Homo sapiens OX=9606 GN=AP3M1","AP3M1",46.939,13.021,12.7,5,7,5,0.918,1.091,1.009,1.091,0.93,0.974,0.992,0.919,"cytoplasm\r","GO:0072384 organelle transport along microtubule; GO:0051640 organelle localization; GO:0046907 intracellular transport; GO:0072594 establishment of protein localization to organelle; GO:0099514 synaptic vesicle cytoskeletal transport; GO:0044699 single-organism process; GO:0006623 protein targeting to vacuole; GO:0048490 anterograde synaptic vesicle transport; GO:0015031 protein transport; GO:0030705 cytoskeleton-dependent intracellular transport; GO:0099111 microtubule-based transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006622 protein targeting to lysosome; GO:0099003 vesicle-mediated transport in synapse; GO:0010970 transport along microtubule; GO:0051649 establishment of localization in cell; GO:1902578 single-organism localization; GO:0072666 establishment of protein localization to vacuole; GO:0099517 synaptic vesicle transport along microtubule; GO:0051648 vesicle localization; GO:0006886 intracellular protein transport; GO:1902580 single-organism cellular localization; GO:0033365 protein localization to organelle; GO:0034613 cellular protein localization; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0009987 cellular process; GO:0008089 anterograde axonal transport; GO:0044765 single-organism transport; GO:0007041 lysosomal transport; GO:0051650 establishment of vesicle localization; GO:0061462 protein localization to lysosome; GO:0048489 synaptic vesicle transport; GO:0016192 vesicle-mediated transport; GO:0098930 axonal transport; GO:0044763 single-organism cellular process; GO:0071702 organic substance transport; GO:0051656 establishment of organelle localization; GO:0007017 microtubule-based process; GO:1902582 single-organism intracellular transport; GO:0047496 vesicle transport along microtubule; GO:0097480 establishment of synaptic vesicle localization; GO:0051641 cellular localization; GO:0072665 protein localization to vacuole; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:0007018 microtubule-based movement; GO:0070727 cellular macromolecule localization; GO:0099518 vesicle cytoskeletal trafficking; GO:0008088 axo-dendritic transport; GO:0007034 vacuolar transport; GO:0097479 synaptic vesicle localization; GO:0006928 movement of cell or subcellular component; GO:0051179 localization; ","GO:0016020 membrane; GO:0030119 AP-type membrane coat adaptor complex; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0098796 membrane protein complex; GO:0099568 cytoplasmic region; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0032838 cell projection cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005765 lysosomal membrane; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005764 lysosome; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0042995 cell projection; GO:0098588 bounding membrane of organelle; GO:0048475 coated membrane; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0044463 cell projection part; GO:0033267 axon part; GO:0030659 cytoplasmic vesicle membrane; GO:0098852 lytic vacuole membrane; GO:0030424 axon; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:1904115 axon cytoplasm; GO:0030131 clathrin adaptor complex; GO:0044437 vacuolar part; GO:0030118 clathrin coat; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0030117 membrane coat; GO:0005794 Golgi apparatus; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0031267 small GTPase binding; GO:0017016 Ras GTPase binding; GO:0005488 binding; GO:0005515 protein binding; GO:0051020 GTPase binding; GO:0019899 enzyme binding; GO:0017137 Rab GTPase binding; ","K12398","AP3M; AP-3 complex subunit mu","hsa04142 Lysosome - Homo sapiens (human); ","IPR028565; IPR011012; IPR022775; ","\"Mu homology domain; Longin-like domain; AP complex, mu/sigma subunit; \"\r"]
["Q9Y2V2","Calcium-regulated heat-stable protein 1 OS=Homo sapiens OX=9606 GN=CARHSP1","CARHSP1",15.892,9.0456,16.3,2,2,2,0.9,0.918,0.857,1.121,1.15,1.049,1.241,0.00322,"cyto_nucl\r","GO:0044700 single organism signaling; GO:0050794 regulation of cellular process; GO:0051716 cellular response to stimulus; GO:0010468 regulation of gene expression; GO:0065008 regulation of biological quality; GO:0006355 regulation of transcription, DNA-templated; GO:0031326 regulation of cellular biosynthetic process; GO:0035556 intracellular signal transduction; GO:0080090 regulation of primary metabolic process; GO:0010608 posttranscriptional regulation of gene expression; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044699 single-organism process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0023052 signaling; GO:0050896 response to stimulus; GO:0031323 regulation of cellular metabolic process; GO:0043488 regulation of mRNA stability; GO:0051252 regulation of RNA metabolic process; GO:0043487 regulation of RNA stability; GO:2001141 regulation of RNA biosynthetic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0007165 signal transduction; GO:0050789 regulation of biological process; GO:0007154 cell communication; GO:0009889 regulation of biosynthetic process; GO:0019222 regulation of metabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0009987 cellular process; GO:0065007 biological regulation; GO:2000112 regulation of cellular macromolecule biosynthetic process; ","GO:0044421 extracellular region part; GO:0031982 vesicle; GO:0000932 P-body; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0045495 pole plasm; GO:0044424 intracellular part; GO:0000177 cytoplasmic exosome (RNase complex); GO:0005623 cell; GO:0043186 P granule; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:1905354 exoribonuclease complex; GO:1902494 catalytic complex; GO:0060293 germ plasm; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0035770 ribonucleoprotein granule; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0000178 exosome (RNase complex); ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003729 mRNA binding; GO:0003677 DNA binding; GO:0003723 RNA binding; GO:0003730 mRNA 3'-UTR binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0019902 phosphatase binding; GO:0019899 enzyme binding; ",{"$nulls":3},"IPR012340; IPR011129; IPR002059; ","\"Nucleic acid-binding, OB-fold; Cold shock domain; Cold-shock protein, DNA-binding; \"\r"]
["Q9Y2W1","Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3","THRAP3",108.66,16.684,4.5,5,5,5,0.846,0.905,0.879,1.164,1.112,1.127,1.294,0.000405,"nucleus\r","GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0000381 regulation of alternative mRNA splicing, via spliceosome; GO:0010608 posttranscriptional regulation of gene expression; GO:0043489 RNA stabilization; GO:0097659 nucleic acid-templated transcription; GO:0009891 positive regulation of biosynthetic process; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0030522 intracellular receptor signaling pathway; GO:0048545 response to steroid hormone; GO:0009719 response to endogenous stimulus; GO:0043170 macromolecule metabolic process; GO:0030518 intracellular steroid hormone receptor signaling pathway; GO:0006396 RNA processing; GO:0051716 cellular response to stimulus; GO:0014070 response to organic cyclic compound; GO:0018130 heterocycle biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0032774 RNA biosynthetic process; GO:0050684 regulation of mRNA processing; GO:0031323 regulation of cellular metabolic process; GO:0071396 cellular response to lipid; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0016071 mRNA metabolic process; GO:0048255 mRNA stabilization; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0033120 positive regulation of RNA splicing; GO:0050794 regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0043487 regulation of RNA stability; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0044248 cellular catabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0008380 RNA splicing; GO:0051254 positive regulation of RNA metabolic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0071407 cellular response to organic cyclic compound; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0043484 regulation of RNA splicing; GO:1903311 regulation of mRNA metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0071383 cellular response to steroid hormone stimulus; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0042752 regulation of circadian rhythm; GO:1901361 organic cyclic compound catabolic process; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0048024 regulation of mRNA splicing, via spliceosome; GO:0070887 cellular response to chemical stimulus; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0030521 androgen receptor signaling pathway; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:1903313 positive regulation of mRNA metabolic process; GO:0016070 RNA metabolic process; GO:0006401 RNA catabolic process; GO:0007623 circadian rhythm; GO:0006397 mRNA processing; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0032870 cellular response to hormone stimulus; GO:0019222 regulation of metabolic process; GO:0050685 positive regulation of mRNA processing; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0006352 DNA-templated transcription, initiation; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0033993 response to lipid; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0006367 transcription initiation from RNA polymerase II promoter; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0006807 nitrogen compound metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0043488 regulation of mRNA stability; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0009755 hormone-mediated signaling pathway; GO:0044249 cellular biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0071495 cellular response to endogenous stimulus; GO:0048511 rhythmic process; GO:0006366 transcription from RNA polymerase II promoter; GO:0009057 macromolecule catabolic process; GO:0048026 positive regulation of mRNA splicing, via spliceosome; GO:0010467 gene expression; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0009725 response to hormone; GO:0042753 positive regulation of circadian rhythm; GO:0043401 steroid hormone mediated signaling pathway; GO:0009056 catabolic process; GO:0065007 biological regulation; GO:0046700 heterocycle catabolic process; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0016592 mediator complex; GO:0016607 nuclear speck; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043230 extracellular organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0046966 thyroid hormone receptor binding; GO:1901265 nucleoside phosphate binding; GO:0005102 receptor binding; GO:0003690 double-stranded DNA binding; GO:0005515 protein binding; GO:0051427 hormone receptor binding; GO:0001047 core promoter binding; GO:1901363 heterocyclic compound binding; GO:0000975 regulatory region DNA binding; GO:0097159 organic cyclic compound binding; GO:0001046 core promoter sequence-specific DNA binding; GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003677 DNA binding; GO:0003723 RNA binding; GO:0042809 vitamin D receptor binding; GO:0005524 ATP binding; GO:0000976 transcription regulatory region sequence-specific DNA binding; GO:1990837 sequence-specific double-stranded DNA binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0043565 sequence-specific DNA binding; GO:0003712 transcription cofactor activity; GO:0051219 phosphoprotein binding; GO:0032549 ribonucleoside binding; GO:0060089 molecular transducer activity; GO:0097367 carbohydrate derivative binding; GO:0001067 regulatory region nucleic acid binding; GO:0001104 RNA polymerase II transcription cofactor activity; GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding; GO:0004872 receptor activity; GO:0044212 transcription regulatory region DNA binding; GO:0003676 nucleic acid binding; GO:0035257 nuclear hormone receptor binding; GO:0032555 purine ribonucleotide binding; GO:0003713 transcription coactivator activity; GO:0001883 purine nucleoside binding; GO:0000988 transcription factor activity, protein binding; GO:0008134 transcription factor binding; GO:0036094 small molecule binding; ","K13112"]
["Q9Y2X0","Mediator of RNA polymerase II transcription subunit 16 OS=Homo sapiens OX=9606 GN=MED16","MED16",96.792,2.2922,2.2,2,3,2,1.175,0.972,0.995,1.118,0.916,0.848,0.917,0.428,"nucleus\r","GO:0044700 single organism signaling; GO:2000273 positive regulation of receptor activity; GO:0097659 nucleic acid-templated transcription; GO:0023051 regulation of signaling; GO:0009891 positive regulation of biosynthetic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0071383 cellular response to steroid hormone stimulus; GO:0010469 regulation of receptor activity; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0044093 positive regulation of molecular function; GO:0030522 intracellular receptor signaling pathway; GO:0048545 response to steroid hormone; GO:0009719 response to endogenous stimulus; GO:0043170 macromolecule metabolic process; GO:0030518 intracellular steroid hormone receptor signaling pathway; GO:0070887 cellular response to chemical stimulus; GO:0010468 regulation of gene expression; GO:0014070 response to organic cyclic compound; GO:0051716 cellular response to stimulus; GO:0018130 heterocycle biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0030521 androgen receptor signaling pathway; GO:0045893 positive regulation of transcription, DNA-templated; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0032774 RNA biosynthetic process; GO:0023052 signaling; GO:0031323 regulation of cellular metabolic process; GO:0071396 cellular response to lipid; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0032870 cellular response to hormone stimulus; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0006352 DNA-templated transcription, initiation; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0071310 cellular response to organic substance; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0033993 response to lipid; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0009059 macromolecule biosynthetic process; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:0006367 transcription initiation from RNA polymerase II promoter; GO:0051254 positive regulation of RNA metabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0071407 cellular response to organic cyclic compound; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:0009755 hormone-mediated signaling pathway; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0071495 cellular response to endogenous stimulus; GO:0006366 transcription from RNA polymerase II promoter; GO:0031325 positive regulation of cellular metabolic process; GO:0010467 gene expression; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0031328 positive regulation of cellular biosynthetic process; GO:0009725 response to hormone; GO:0043401 steroid hormone mediated signaling pathway; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031974 membrane-enclosed lumen; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0016592 mediator complex; GO:0005622 intracellular; GO:0044464 cell part; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0030546 receptor activator activity; GO:0010861 thyroid hormone receptor activator activity; GO:0042809 vitamin D receptor binding; GO:0046966 thyroid hormone receptor binding; GO:0005102 receptor binding; GO:0005515 protein binding; GO:0051427 hormone receptor binding; GO:0098772 molecular function regulator; GO:0003712 transcription cofactor activity; GO:0060089 molecular transducer activity; GO:0030545 receptor regulator activity; GO:0004872 receptor activity; GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity; GO:0003824 catalytic activity; GO:0030375 thyroid hormone receptor coactivator activity; GO:0005488 binding; GO:0035257 nuclear hormone receptor binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0003713 transcription coactivator activity; GO:0000988 transcription factor activity, protein binding; GO:0008134 transcription factor binding; ","K15159","MED16; mediator of RNA polymerase II transcription subunit 16","hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human); ","IPR017986; IPR011041; IPR015943; ","WD40-repeat-containing domain; Soluble quinoprotein glucose/sorbosone dehydrogenase; WD40/YVTN repeat-like-containing domain; \r"]
["Q9Y2X3","Nucleolar protein 58 OS=Homo sapiens OX=9606 GN=NOP58","NOP58",59.578,25.267,14.7,6,7,6,1.008,0.999,0.938,1.034,0.965,1.058,1.038,0.358,"cytoplasm\r","GO:0050658 RNA transport; GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0072594 establishment of protein localization to organelle; GO:0017038 protein import; GO:0044699 single-organism process; GO:0051169 nuclear transport; GO:0044237 cellular metabolic process; GO:0009451 RNA modification; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0050657 nucleic acid transport; GO:0015931 nucleobase-containing compound transport; GO:0006364 rRNA processing; GO:0033365 protein localization to organelle; GO:0043170 macromolecule metabolic process; GO:0008104 protein localization; GO:0006606 protein import into nucleus; GO:0033036 macromolecule localization; GO:0044765 single-organism transport; GO:0034470 ncRNA processing; GO:0006396 RNA processing; GO:0016072 rRNA metabolic process; GO:0016049 cell growth; GO:0044763 single-organism cellular process; GO:0042254 ribosome biogenesis; GO:1901360 organic cyclic compound metabolic process; GO:0006404 RNA import into nucleus; GO:1902582 single-organism intracellular transport; GO:0071166 ribonucleoprotein complex localization; GO:0006810 transport; GO:0016070 RNA metabolic process; GO:0048254 snoRNA localization; GO:0090304 nucleic acid metabolic process; GO:0006608 snRNP protein import into nucleus; GO:0044260 cellular macromolecule metabolic process; GO:0006913 nucleocytoplasmic transport; GO:0046907 intracellular transport; GO:0006725 cellular aromatic compound metabolic process; GO:1902593 single-organism nuclear import; GO:0000154 rRNA modification; GO:0051236 establishment of RNA localization; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:1902578 single-organism localization; GO:0006139 nucleobase-containing compound metabolic process; GO:0006886 intracellular protein transport; GO:0044744 protein targeting to nucleus; GO:0034641 cellular nitrogen compound metabolic process; GO:1902580 single-organism cellular localization; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0006403 RNA localization; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0051170 nuclear import; GO:0071167 ribonucleoprotein complex import into nucleus; GO:0010467 gene expression; GO:0043412 macromolecule modification; GO:0051179 localization; GO:0034504 protein localization to nucleus; GO:0034660 ncRNA metabolic process; GO:0040007 growth; GO:0071705 nitrogen compound transport; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0015030 Cajal body; GO:0044422 organelle part; GO:0030684 preribosome; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0032040 small-subunit processome; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044452 nucleolar part; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0001650 fibrillar center; GO:0070761 pre-snoRNP complex; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0005732 small nucleolar ribonucleoprotein complex; GO:0031428 box C/D snoRNP complex; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0030515 snoRNA binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0001099 basal RNA polymerase II transcription machinery binding; GO:0001098 basal transcription machinery binding; GO:0051117 ATPase binding; GO:0001085 RNA polymerase II transcription factor binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0001091 RNA polymerase II basal transcription factor binding; GO:0005515 protein binding; GO:0008134 transcription factor binding; GO:0019899 enzyme binding; GO:0001094 TFIID-class transcription factor binding; ","K14565","NOP58; nucleolar protein 58","hsa03008 Ribosome biogenesis in eukaryotes - Homo sapiens (human); ","IPR002687; IPR012974; IPR012976; ","\"Nop domain; NOP5, N-terminal; NOSIC; \"\r"]
["Q9Y2X7","ARF GTPase-activating protein GIT1 OS=Homo sapiens OX=9606 GN=GIT1","GIT1",84.34,2.7711,2.9,2,2,2,1.081,1.106,0.997,0.994,0.858,0.984,0.891,0.109,"mitochondria\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0007166 cell surface receptor signaling pathway; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0010564 regulation of cell cycle process; GO:0032465 regulation of cytokinesis; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0048013 ephrin receptor signaling pathway; GO:0007154 cell communication; GO:0051345 positive regulation of hydrolase activity; GO:0044093 positive regulation of molecular function; GO:0051726 regulation of cell cycle; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0051716 cellular response to stimulus; GO:0043547 positive regulation of GTPase activity; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0008277 regulation of G-protein coupled receptor protein signaling pathway; GO:0023052 signaling; GO:0043085 positive regulation of catalytic activity; GO:0050789 regulation of biological process; GO:0051302 regulation of cell division; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0065009 regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005925 focal adhesion; GO:0044464 cell part; GO:0005622 intracellular; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0005912 adherens junction; GO:0070161 anchoring junction; GO:0030055 cell-substrate junction; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044444 cytoplasmic part; GO:0005924 cell-substrate adherens junction; ","GO:0030234 enzyme regulator activity; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0030695 GTPase regulator activity; GO:0043167 ion binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0008047 enzyme activator activity; GO:0032403 protein complex binding; GO:0005096 GTPase activator activity; ","K05737","GIT1; G protein-coupled receptor kinase interactor 1","hsa05120 Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human); hsa04144 Endocytosis - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); ","IPR022018; IPR013724; IPR020683; IPR032352; ","\"ARF GTPase-activating protein GIT1, C-terminal; GIT, Spa2 homology (SHD) domain; Ankyrin repeat-containing domain; Arf GTPase-activating protein GIT1/2, coiled-coil domain; \"\r"]
["Q9Y2Z0","Protein SGT1 homolog OS=Homo sapiens OX=9606 GN=SUGT1","SUGT1",41.024,41.252,30.4,8,8,8,0.853,0.91,1.041,1.047,1.072,1.072,1.138,0.154,"cytoplasm\r","GO:0016043 cellular component organization; GO:0043947 positive regulation by host of symbiont catalytic activity; GO:0065008 regulation of biological quality; GO:0007067 mitotic nuclear division; GO:0048285 organelle fission; GO:0044359 modulation of molecular function in other organism; GO:0044699 single-organism process; GO:0052422 modulation by host of symbiont catalytic activity; GO:0035821 modification of morphology or physiology of other organism; GO:1903047 mitotic cell cycle process; GO:0044362 negative regulation of molecular function in other organism; GO:0051817 modification of morphology or physiology of other organism involved in symbiotic interaction; GO:0044093 positive regulation of molecular function; GO:0044003 modification by symbiont of host morphology or physiology; GO:0051702 interaction with symbiont; GO:0044419 interspecies interaction between organisms; GO:0009987 cellular process; GO:0052428 modification by host of symbiont molecular function; GO:0000278 mitotic cell cycle; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0051701 interaction with host; GO:0043946 positive regulation of catalytic activity in other organism involved in symbiotic interaction; GO:0051704 multi-organism process; GO:0043085 positive regulation of catalytic activity; GO:0052055 modulation by symbiont of host molecular function; GO:0052205 modulation of molecular function in other organism involved in symbiotic interaction; GO:0052405 negative regulation by host of symbiont molecular function; GO:0052204 negative regulation of molecular function in other organism involved in symbiotic interaction; GO:0050790 regulation of catalytic activity; GO:0006996 organelle organization; GO:0000280 nuclear division; GO:0065009 regulation of molecular function; GO:0052203 modulation of catalytic activity in other organism involved in symbiotic interaction; GO:0044092 negative regulation of molecular function; GO:0031647 regulation of protein stability; GO:0022402 cell cycle process; GO:0007049 cell cycle; GO:0051851 modification by host of symbiont morphology or physiology; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:1990234 transferase complex; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0044427 chromosomal part; GO:0098687 chromosomal region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:1902494 catalytic complex; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0000775 chromosome, centromeric region; GO:0043227 membrane-bounded organelle; GO:0043234 protein complex; GO:0000151 ubiquitin ligase complex; GO:0000776 kinetochore; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ","K12795","SUGT1; suppressor of G2 allele of SKP1","hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human); ","IPR007052; IPR011990; IPR007699; IPR013026; IPR008978; ","CS domain; Tetratricopeptide-like helical domain; SGS domain; Tetratricopeptide repeat-containing domain; HSP20-like chaperone; \r"]
["Q9Y2Z4","Tyrosine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=YARS2","YARS2",53.198,21.515,6.1,2,2,2,1.027,1.02,0.936,0.951,1.124,0.95,1.014,0.863,"mitochondria\r","GO:0006518 peptide metabolic process; GO:0070127 tRNA aminoacylation for mitochondrial protein translation; GO:0006725 cellular aromatic compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0070184 mitochondrial tyrosyl-tRNA aminoacylation; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0043039 tRNA aminoacylation; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0006418 tRNA aminoacylation for protein translation; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0006412 translation; GO:0009987 cellular process; GO:0000959 mitochondrial RNA metabolic process; GO:0043043 peptide biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0032543 mitochondrial translation; GO:0043603 cellular amide metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0016070 RNA metabolic process; GO:0006399 tRNA metabolic process; GO:0090304 nucleic acid metabolic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0044710 single-organism metabolic process; GO:0006437 tyrosyl-tRNA aminoacylation; GO:0043038 amino acid activation; GO:0019752 carboxylic acid metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0006082 organic acid metabolic process; GO:0034660 ncRNA metabolic process; GO:0043436 oxoacid metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0016604 nuclear body; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds; GO:0016597 amino acid binding; GO:1901265 nucleoside phosphate binding; GO:0016875 ligase activity, forming carbon-oxygen bonds; GO:0046983 protein dimerization activity; GO:0016874 ligase activity; GO:0005515 protein binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0042802 identical protein binding; GO:0031406 carboxylic acid binding; GO:0000049 tRNA binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0004831 tyrosine-tRNA ligase activity; GO:0004812 aminoacyl-tRNA ligase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003723 RNA binding; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0043177 organic acid binding; GO:0000166 nucleotide binding; GO:0072545 tyrosine binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0042803 protein homodimerization activity; GO:0003676 nucleic acid binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; ","K01866","YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]","hsa00970 Aminoacyl-tRNA biosynthesis - Homo sapiens (human); ","IPR014729; IPR002942; ","Rossmann-like alpha/beta/alpha sandwich fold; RNA-binding S4 domain; \r"]
["Q9Y303","N-acetylglucosamine-6-phosphate deacetylase OS=Homo sapiens OX=9606 GN=AMDHD2","AMDHD2",43.747,2.1415,2.9,1,1,1,1.052,0.976,0.937,0.963,1.042,1.037,1.026,0.571,"mitochondria\r","GO:0009226 nucleotide-sugar biosynthetic process; GO:1901071 glucosamine-containing compound metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0019262 N-acetylneuraminate catabolic process; GO:0046348 amino sugar catabolic process; GO:0044248 cellular catabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009987 cellular process; GO:0006047 UDP-N-acetylglucosamine metabolic process; GO:0018130 heterocycle biosynthetic process; GO:0044712 single-organism catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:1901136 carbohydrate derivative catabolic process; GO:0044282 small molecule catabolic process; GO:0006048 UDP-N-acetylglucosamine biosynthetic process; GO:0044238 primary metabolic process; GO:0005975 carbohydrate metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0046395 carboxylic acid catabolic process; GO:1901575 organic substance catabolic process; GO:0006044 N-acetylglucosamine metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006793 phosphorus metabolic process; GO:0044710 single-organism metabolic process; GO:0016054 organic acid catabolic process; GO:0019752 carboxylic acid metabolic process; GO:0006040 amino sugar metabolic process; GO:0009225 nucleotide-sugar metabolic process; GO:0006054 N-acetylneuraminate metabolic process; GO:0006082 organic acid metabolic process; GO:0009056 catabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0043436 oxoacid metabolic process; GO:0046349 amino sugar biosynthetic process; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0044444 cytoplasmic part; ","GO:0008448 N-acetylglucosamine-6-phosphate deacetylase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0019213 deacetylase activity; GO:0016787 hydrolase activity; GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; ","K01443","nagA; N-acetylglucosamine-6-phosphate deacetylase [EC:3.5.1.25]","hsa00520 Amino sugar and nucleotide sugar metabolism - Homo sapiens (human); ","IPR032466; IPR006680; IPR011059; ","\"Metal-dependent hydrolase; Amidohydrolase-related; Metal-dependent hydrolase, composite domain; \"\r"]
["Q9Y305","Acyl-coenzyme A thioesterase 9, mitochondrial OS=Homo sapiens OX=9606 GN=ACOT9","ACOT9",49.901,26.185,17.1,7,10,7,1.02,1.064,1.024,0.934,0.963,0.968,0.922,0.00966,"mitochondria\r","GO:0006790 sulfur compound metabolic process; GO:0051188 cofactor biosynthetic process; GO:0046949 fatty-acyl-CoA biosynthetic process; GO:0071616 acyl-CoA biosynthetic process; GO:0035337 fatty-acyl-CoA metabolic process; GO:0035383 thioester metabolic process; GO:0006732 coenzyme metabolic process; GO:0009058 biosynthetic process; GO:0035336 long-chain fatty-acyl-CoA metabolic process; GO:0044237 cellular metabolic process; GO:0035338 long-chain fatty-acyl-CoA biosynthetic process; GO:1901576 organic substance biosynthetic process; GO:0006637 acyl-CoA metabolic process; GO:0044249 cellular biosynthetic process; GO:0035384 thioester biosynthetic process; GO:0044272 sulfur compound biosynthetic process; GO:0051186 cofactor metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0006793 phosphorus metabolic process; GO:0009108 coenzyme biosynthetic process; GO:0009987 cellular process; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0052689 carboxylic ester hydrolase activity; GO:0003824 catalytic activity; GO:0003986 acetyl-CoA hydrolase activity; GO:0016788 hydrolase activity, acting on ester bonds; GO:0047617 acyl-CoA hydrolase activity; GO:0016289 CoA hydrolase activity; GO:0016787 hydrolase activity; GO:0016790 thiolester hydrolase activity; ","K17361",null,null,"IPR029069; IPR033120; ","HotDog domain; Hotdog acyl-CoA thioesterase (ACOT)-type domain; \r"]
["Q9Y315","Deoxyribose-phosphate aldolase OS=Homo sapiens OX=9606 GN=DERA","DERA",35.23,61.489,36.8,10,15,10,0.944,1.002,0.983,1.009,0.972,1.03,1.028,0.321,"cytoplasm\r","GO:0006739 NADP metabolic process; GO:0009116 nucleoside metabolic process; GO:0019362 pyridine nucleotide metabolic process; GO:0045321 leukocyte activation; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0009262 deoxyribonucleotide metabolic process; GO:0072524 pyridine-containing compound metabolic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0019692 deoxyribose phosphate metabolic process; GO:1901292 nucleoside phosphate catabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0006098 pentose-phosphate shunt; GO:0019693 ribose phosphate metabolic process; GO:1901361 organic cyclic compound catabolic process; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0002443 leukocyte mediated immunity; GO:0006733 oxidoreduction coenzyme metabolic process; GO:0002446 neutrophil mediated immunity; GO:0009166 nucleotide catabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0006081 cellular aldehyde metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0006732 coenzyme metabolic process; GO:0005975 carbohydrate metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0051186 cofactor metabolic process; GO:0016052 carbohydrate catabolic process; GO:0006810 transport; GO:0019439 aromatic compound catabolic process; GO:1901575 organic substance catabolic process; GO:0032940 secretion by cell; GO:0044710 single-organism metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0043299 leukocyte degranulation; GO:0046121 deoxyribonucleoside catabolic process; GO:0002283 neutrophil activation involved in immune response; GO:0006725 cellular aromatic compound metabolic process; GO:0046496 nicotinamide nucleotide metabolic process; GO:0046434 organophosphate catabolic process; GO:0002252 immune effector process; GO:0050896 response to stimulus; GO:0046386 deoxyribose phosphate catabolic process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0051156 glucose 6-phosphate metabolic process; GO:0046483 heterocycle metabolic process; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0019682 glyceraldehyde-3-phosphate metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0036230 granulocyte activation; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0044712 single-organism catabolic process; GO:0009264 deoxyribonucleotide catabolic process; GO:0016192 vesicle-mediated transport; GO:1901658 glycosyl compound catabolic process; GO:0006807 nitrogen compound metabolic process; GO:1901136 carbohydrate derivative catabolic process; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:0043312 neutrophil degranulation; GO:0002263 cell activation involved in immune response; GO:0009120 deoxyribonucleoside metabolic process; GO:0002366 leukocyte activation involved in immune response; GO:0042119 neutrophil activation; GO:0045055 regulated exocytosis; GO:1901565 organonitrogen compound catabolic process; GO:0006793 phosphorus metabolic process; GO:0019637 organophosphate metabolic process; GO:0001775 cell activation; GO:0009164 nucleoside catabolic process; GO:0006955 immune response; GO:0051179 localization; GO:0009056 catabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0006887 exocytosis; GO:0046700 heterocycle catabolic process; ","GO:0034774 secretory granule lumen; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0060205 cytoplasmic vesicle lumen; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016829 lyase activity; GO:0004139 deoxyribose-phosphate aldolase activity; GO:0016832 aldehyde-lyase activity; GO:0003824 catalytic activity; GO:0016830 carbon-carbon lyase activity; ","K01619","deoC; deoxyribose-phosphate aldolase [EC:4.1.2.4]","hsa00030 Pentose phosphate pathway - Homo sapiens (human); ","IPR013785; ","Aldolase-type TIM barrel; \r"]
["Q9Y333","U6 snRNA-associated Sm-like protein LSm2 OS=Homo sapiens OX=9606 GN=LSM2","LSM2",10.834,50.692,60,4,5,4,0.947,0.965,1.021,0.982,0.992,1.095,1.046,0.342,"cytoplasm\r","GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0048519 negative regulation of biological process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0008152 metabolic process; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0044248 cellular catabolic process; GO:1901361 organic cyclic compound catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0043170 macromolecule metabolic process; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0006396 RNA processing; GO:0010468 regulation of gene expression; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; GO:0006401 RNA catabolic process; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0050789 regulation of biological process; GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; GO:0090304 nucleic acid metabolic process; GO:0009057 macromolecule catabolic process; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0010467 gene expression; GO:0009056 catabolic process; GO:0016071 mRNA metabolic process; GO:0065007 biological regulation; GO:0046700 heterocycle catabolic process; ","GO:0000932 P-body; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0071011 precatalytic spliceosome; GO:0044422 organelle part; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0097526 spliceosomal tri-snRNP complex; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:1990726 Lsm1-7-Pat1 complex; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0046540 U4/U6 x U5 tri-snRNP complex; GO:0031981 nuclear lumen; GO:0005681 spliceosomal complex; GO:0005829 cytosol; GO:0097525 spliceosomal snRNP complex; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0035770 ribonucleoprotein granule; GO:0071013 catalytic step 2 spliceosome; GO:1990904 ribonucleoprotein complex; GO:0005688 U6 snRNP; GO:0043234 protein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0030532 small nuclear ribonucleoprotein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0031267 small GTPase binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0017016 Ras GTPase binding; GO:0017070 U6 snRNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0051020 GTPase binding; GO:0017160 Ral GTPase binding; GO:0017069 snRNA binding; GO:0019899 enzyme binding; ","K12621","LSM2; U6 snRNA-associated Sm-like protein LSm2","hsa03018 RNA degradation - Homo sapiens (human); hsa03040 Spliceosome - Homo sapiens (human); ","IPR001163; IPR010920; ","\"LSM domain, eukaryotic/archaea-type; LSM domain; \"\r"]
["Q9Y365","START domain-containing protein 10 OS=Homo sapiens OX=9606 GN=STARD10","STARD10",33.048,18.185,10,2,2,2,1.047,0.984,0.998,1.013,1.006,0.964,0.985,0.567,"cytoplasm\r","GO:0046470 phosphatidylcholine metabolic process; GO:0046717 acid secretion; GO:0015850 organic hydroxy compound transport; GO:0046486 glycerolipid metabolic process; GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway; GO:0023051 regulation of signaling; GO:0008654 phospholipid biosynthetic process; GO:0035358 regulation of peroxisome proliferator activated receptor signaling pathway; GO:0044699 single-organism process; GO:0044255 cellular lipid metabolic process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0008610 lipid biosynthetic process; GO:0051234 establishment of localization; GO:0008152 metabolic process; GO:0010646 regulation of cell communication; GO:0015718 monocarboxylic acid transport; GO:0006650 glycerophospholipid metabolic process; GO:0033036 macromolecule localization; GO:0006656 phosphatidylcholine biosynthetic process; GO:0006629 lipid metabolic process; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0006869 lipid transport; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0046942 carboxylic acid transport; GO:0090407 organophosphate biosynthetic process; GO:0006810 transport; GO:0050789 regulation of biological process; GO:0044710 single-organism metabolic process; GO:0046474 glycerophospholipid biosynthetic process; GO:0048583 regulation of response to stimulus; GO:0050794 regulation of cellular process; GO:0015721 bile acid and bile salt transport; GO:0097164 ammonium ion metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0032782 bile acid secretion; GO:1902578 single-organism localization; GO:0023056 positive regulation of signaling; GO:0010647 positive regulation of cell communication; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:0044711 single-organism biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0010876 lipid localization; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0015849 organic acid transport; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0045017 glycerolipid biosynthetic process; GO:0006820 anion transport; GO:0015711 organic anion transport; GO:0006793 phosphorus metabolic process; GO:0006811 ion transport; GO:0019637 organophosphate metabolic process; GO:0006644 phospholipid metabolic process; GO:0009967 positive regulation of signal transduction; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:1901564 organonitrogen compound metabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0042995 cell projection; GO:0005622 intracellular; GO:0046581 intercellular canaliculus; GO:0030054 cell junction; GO:0044464 cell part; GO:0005737 cytoplasm; GO:0005902 microvillus; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0098858 actin-based cell projection; GO:0005623 cell; GO:0005911 cell-cell junction; GO:0044444 cytoplasmic part; ","GO:0008289 lipid binding; GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR002913; IPR023393; ","START domain; START-like domain; \r"]
["Q9Y371","Endophilin-B1 OS=Homo sapiens OX=9606 GN=SH3GLB1","SH3GLB1",40.796,38.008,22.7,8,12,7,1.012,1.015,0.992,1.058,0.943,0.963,0.982,0.616,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:1903955 positive regulation of protein targeting to mitochondrion; GO:1903533 regulation of protein targeting; GO:0031331 positive regulation of cellular catabolic process; GO:0044699 single-organism process; GO:0006914 autophagy; GO:1902115 regulation of organelle assembly; GO:0032459 regulation of protein oligomerization; GO:0010564 regulation of cell cycle process; GO:0044237 cellular metabolic process; GO:0010821 regulation of mitochondrion organization; GO:1903749 positive regulation of establishment of protein localization to mitochondrion; GO:0051130 positive regulation of cellular component organization; GO:1903729 regulation of plasma membrane organization; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0032879 regulation of localization; GO:1903747 regulation of establishment of protein localization to mitochondrion; GO:0006915 apoptotic process; GO:0032461 positive regulation of protein oligomerization; GO:0031334 positive regulation of protein complex assembly; GO:0043170 macromolecule metabolic process; GO:0033365 protein localization to organelle; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0051726 regulation of cell cycle; GO:0051716 cellular response to stimulus; GO:0044088 regulation of vacuole organization; GO:0071822 protein complex subunit organization; GO:0043112 receptor metabolic process; GO:0072657 protein localization to membrane; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0032386 regulation of intracellular transport; GO:0031323 regulation of cellular metabolic process; GO:0010506 regulation of autophagy; GO:0051050 positive regulation of transport; GO:0016241 regulation of macroautophagy; GO:0072665 protein localization to vacuole; GO:2000785 regulation of autophagosome assembly; GO:0032801 receptor catabolic process; GO:1901575 organic substance catabolic process; GO:0043254 regulation of protein complex assembly; GO:0051302 regulation of cell division; GO:0050789 regulation of biological process; GO:1903527 positive regulation of membrane tubulation; GO:0010638 positive regulation of organelle organization; GO:1902117 positive regulation of organelle assembly; GO:0010508 positive regulation of autophagy; GO:0044260 cellular macromolecule metabolic process; GO:0016239 positive regulation of macroautophagy; GO:0019222 regulation of metabolic process; GO:0051223 regulation of protein transport; GO:0070271 protein complex biogenesis; GO:2000786 positive regulation of autophagosome assembly; GO:0051222 positive regulation of protein transport; GO:0034198 cellular response to amino acid starvation; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0016043 cellular component organization; GO:0009267 cellular response to starvation; GO:0090316 positive regulation of intracellular protein transport; GO:1903829 positive regulation of cellular protein localization; GO:0090148 membrane fission; GO:0044087 regulation of cellular component biogenesis; GO:0050896 response to stimulus; GO:0032465 regulation of cytokinesis; GO:0031669 cellular response to nutrient levels; GO:0070201 regulation of establishment of protein localization; GO:0071704 organic substance metabolic process; GO:0051259 protein oligomerization; GO:0060341 regulation of cellular localization; GO:1903525 regulation of membrane tubulation; GO:0009991 response to extracellular stimulus; GO:0009896 positive regulation of catabolic process; GO:0044248 cellular catabolic process; GO:0032880 regulation of protein localization; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0033157 regulation of intracellular protein transport; GO:0006461 protein complex assembly; GO:0006950 response to stress; GO:0042149 cellular response to glucose starvation; GO:0032388 positive regulation of intracellular transport; GO:0051049 regulation of transport; GO:0033043 regulation of organelle organization; GO:0044802 single-organism membrane organization; GO:0071496 cellular response to external stimulus; GO:1903214 regulation of protein targeting to mitochondrion; GO:1903778 protein localization to vacuolar membrane; GO:0048518 positive regulation of biological process; GO:0048102 autophagic cell death; GO:0051641 cellular localization; GO:0043933 macromolecular complex subunit organization; GO:0031668 cellular response to extracellular stimulus; GO:0010822 positive regulation of mitochondrion organization; GO:0070727 cellular macromolecule localization; GO:1904951 positive regulation of establishment of protein localization; GO:0008219 cell death; GO:0031325 positive regulation of cellular metabolic process; GO:0009057 macromolecule catabolic process; GO:0061024 membrane organization; GO:0044090 positive regulation of vacuole organization; GO:0042594 response to starvation; GO:0031647 regulation of protein stability; GO:0012501 programmed cell death; GO:0031667 response to nutrient levels; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0009056 catabolic process; GO:0044089 positive regulation of cellular component biogenesis; GO:1903827 regulation of cellular protein localization; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0019867 outer membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005776 autophagosome; GO:0005740 mitochondrial envelope; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0031968 organelle outer membrane; GO:0043227 membrane-bounded organelle; GO:0000421 autophagosome membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0044429 mitochondrial part; GO:0005741 mitochondrial outer membrane; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0030496 midbody; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031975 envelope; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0005794 Golgi apparatus; GO:0031966 mitochondrial membrane; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0050839 cell adhesion molecule binding; GO:0042802 identical protein binding; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0046983 protein dimerization activity; GO:0045296 cadherin binding; GO:0008289 lipid binding; GO:0005515 protein binding; ","K11248","SH3GLB1; endophilin-B1","hsa04144 Endocytosis - Homo sapiens (human); hsa04140 Autophagy - animal - Homo sapiens (human); ","IPR001452; IPR027267; IPR004148; ","SH3 domain; Arfaptin homology (AH) domain/BAR domain; BAR domain; \r"]
["Q9Y376","Calcium-binding protein 39 OS=Homo sapiens OX=9606 GN=CAB39","CAB39",39.869,18.996,24.6,9,11,8,0.94,0.922,0.921,1.123,1.059,1.1,1.179,0.000863,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0045321 leukocyte activation; GO:0032270 positive regulation of cellular protein metabolic process; GO:2000681 negative regulation of rubidium ion transport; GO:1901017 negative regulation of potassium ion transmembrane transporter activity; GO:0006971 hypotonic response; GO:0044237 cellular metabolic process; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0008152 metabolic process; GO:0065003 macromolecular complex assembly; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0010800 positive regulation of peptidyl-threonine phosphorylation; GO:0018105 peptidyl-serine phosphorylation; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0051347 positive regulation of transferase activity; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0051051 negative regulation of transport; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0051174 regulation of phosphorus metabolic process; GO:0071214 cellular response to abiotic stimulus; GO:0080090 regulation of primary metabolic process; GO:0043269 regulation of ion transport; GO:0044763 single-organism cellular process; GO:0031323 regulation of cellular metabolic process; GO:0051291 protein heterooligomerization; GO:0006810 transport; GO:0034762 regulation of transmembrane transport; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0071470 cellular response to osmotic stress; GO:0006464 cellular protein modification process; GO:0032412 regulation of ion transmembrane transporter activity; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0016310 phosphorylation; GO:0043267 negative regulation of potassium ion transport; GO:2000680 regulation of rubidium ion transport; GO:0002283 neutrophil activation involved in immune response; GO:1901380 negative regulation of potassium ion transmembrane transport; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:2000686 regulation of rubidium ion transmembrane transporter activity; GO:0071902 positive regulation of protein serine/threonine kinase activity; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0051259 protein oligomerization; GO:0032147 activation of protein kinase activity; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0051338 regulation of transferase activity; GO:0010959 regulation of metal ion transport; GO:0006461 protein complex assembly; GO:0032409 regulation of transporter activity; GO:1904062 regulation of cation transmembrane transport; GO:0023014 signal transduction by protein phosphorylation; GO:0034763 negative regulation of transmembrane transport; GO:0006950 response to stress; GO:0016192 vesicle-mediated transport; GO:1901379 regulation of potassium ion transmembrane transport; GO:0002376 immune system process; GO:0071476 cellular hypotonic response; GO:0044238 primary metabolic process; GO:0002263 cell activation involved in immune response; GO:0034766 negative regulation of ion transmembrane transport; GO:0045055 regulated exocytosis; GO:0051247 positive regulation of protein metabolic process; GO:0006793 phosphorus metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0001775 cell activation; GO:0051179 localization; GO:0006955 immune response; GO:0043412 macromolecule modification; GO:0006887 exocytosis; GO:0018209 peptidyl-serine modification; GO:0044699 single-organism process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:0043266 regulation of potassium ion transport; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0009893 positive regulation of metabolic process; GO:0032413 negative regulation of ion transmembrane transporter activity; GO:0033674 positive regulation of kinase activity; GO:0051726 regulation of cell cycle; GO:0002274 myeloid leukocyte activation; GO:0071822 protein complex subunit organization; GO:0006970 response to osmotic stress; GO:0045937 positive regulation of phosphate metabolic process; GO:0002446 neutrophil mediated immunity; GO:0048522 positive regulation of cellular process; GO:0022898 regulation of transmembrane transporter activity; GO:0023052 signaling; GO:0002444 myeloid leukocyte mediated immunity; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0032940 secretion by cell; GO:1901016 regulation of potassium ion transmembrane transporter activity; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0043299 leukocyte degranulation; GO:0019220 regulation of phosphate metabolic process; GO:0070271 protein complex biogenesis; GO:0036211 protein modification process; GO:0043549 regulation of kinase activity; GO:0045859 regulation of protein kinase activity; GO:0016043 cellular component organization; GO:0045786 negative regulation of cell cycle; GO:0010799 regulation of peptidyl-threonine phosphorylation; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0006468 protein phosphorylation; GO:0032410 negative regulation of transporter activity; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0043271 negative regulation of ion transport; GO:0035556 intracellular signal transduction; GO:0007050 cell cycle arrest; GO:0051049 regulation of transport; GO:0001932 regulation of protein phosphorylation; GO:0031401 positive regulation of protein modification process; GO:0001934 positive regulation of protein phosphorylation; GO:0045860 positive regulation of protein kinase activity; GO:0043312 neutrophil degranulation; GO:0048518 positive regulation of biological process; GO:0043933 macromolecular complex subunit organization; GO:0043085 positive regulation of catalytic activity; GO:0018193 peptidyl-amino acid modification; GO:0002366 leukocyte activation involved in immune response; GO:1904063 negative regulation of cation transmembrane transport; GO:2000687 negative regulation of rubidium ion transmembrane transporter activity; GO:0042119 neutrophil activation; GO:0034765 regulation of ion transmembrane transport; GO:0051246 regulation of protein metabolic process; GO:0022402 cell cycle process; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0044421 extracellular region part; GO:0061695 transferase complex, transferring phosphorus-containing groups; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:1902554 serine/threonine protein kinase complex; GO:0005623 cell; GO:1904813 ficolin-1-rich granule lumen; GO:1902911 protein kinase complex; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0101002 ficolin-1-rich granule; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:1990234 transferase complex; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0043226 organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0043539 protein serine/threonine kinase activator activity; GO:0030295 protein kinase activator activity; GO:0005515 protein binding; GO:0004672 protein kinase activity; GO:0019207 kinase regulator activity; GO:0019887 protein kinase regulator activity; GO:0019900 kinase binding; GO:0098772 molecular function regulator; GO:0019209 kinase activator activity; GO:0016301 kinase activity; GO:0030234 enzyme regulator activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0004674 protein serine/threonine kinase activity; GO:0016740 transferase activity; GO:0008047 enzyme activator activity; GO:0019899 enzyme binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K08272","CAB39; calcium binding protein 39","hsa04150 mTOR signaling pathway - Homo sapiens (human); hsa04152 AMPK signaling pathway - Homo sapiens (human); ","IPR011989; IPR016024; ","Armadillo-like helical; Armadillo-type fold; \r"]
["Q9Y383","Putative RNA-binding protein Luc7-like 2 OS=Homo sapiens OX=9606 GN=LUC7L2","LUC7L2",46.513,43.559,18.9,8,13,5,0.966,0.869,1.023,1,1.054,1.029,1.079,0.196,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0006376 mRNA splice site selection; GO:0016043 cellular component organization; GO:0022613 ribonucleoprotein complex biogenesis; GO:0022618 ribonucleoprotein complex assembly; GO:0006725 cellular aromatic compound metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0008152 metabolic process; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0071826 ribonucleoprotein complex subunit organization; GO:0006139 nucleobase-containing compound metabolic process; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0000375 RNA splicing, via transesterification reactions; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0009987 cellular process; GO:0008380 RNA splicing; GO:0006396 RNA processing; GO:0034622 cellular macromolecular complex assembly; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:0090304 nucleic acid metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0000245 spliceosomal complex assembly; GO:0016071 mRNA metabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0005685 U1 snRNP; GO:0043229 intracellular organelle; GO:0044446 intracellular organelle part; GO:0005684 U2-type spliceosomal complex; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005681 spliceosomal complex; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0097525 spliceosomal snRNP complex; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0044464 cell part; GO:0005622 intracellular; GO:0071010 prespliceosome; GO:0071004 U2-type prespliceosome; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0030532 small nuclear ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003729 mRNA binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0019899 enzyme binding; ","K13212"]
["Q9Y394","Dehydrogenase/reductase SDR family member 7 OS=Homo sapiens OX=9606 GN=DHRS7","DHRS7",38.298,62.011,16.2,4,6,4,1.013,1.034,0.982,1.122,0.906,0.955,0.985,0.785,"endoplasmic reticulum\r","GO:0044699 single-organism process; GO:0008152 metabolic process; GO:0055114 oxidation-reduction process; GO:0044710 single-organism metabolic process; ","GO:0016020 membrane; ","GO:0003824 catalytic activity; GO:0016491 oxidoreductase activity; ","K11165",null,null,"IPR016040; ","NAD(P)-binding domain; \r"]
["Q9Y3A5","Ribosome maturation protein SBDS OS=Homo sapiens OX=9606 GN=SBDS","SBDS",28.763,53.129,41.6,12,20,12,0.99,0.936,0.955,1.045,1.022,1.048,1.081,0.0127,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0051674 localization of cell; GO:0022618 ribonucleoprotein complex assembly; GO:0043009 chordate embryonic development; GO:0007067 mitotic nuclear division; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0071826 ribonucleoprotein complex subunit organization; GO:0022607 cellular component assembly; GO:0006364 rRNA processing; GO:0065003 macromolecular complex assembly; GO:0001833 inner cell mass cell proliferation; GO:0043170 macromolecule metabolic process; GO:0009790 embryo development; GO:0070887 cellular response to chemical stimulus; GO:0016072 rRNA metabolic process; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0032502 developmental process; GO:0048539 bone marrow development; GO:0000278 mitotic cell cycle; GO:0051716 cellular response to stimulus; GO:0009888 tissue development; GO:0001503 ossification; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0042254 ribosome biogenesis; GO:0002520 immune system development; GO:0048870 cell motility; GO:0006935 chemotaxis; GO:0032501 multicellular organismal process; GO:0042256 mature ribosome assembly; GO:0016070 RNA metabolic process; GO:0000226 microtubule cytoskeleton organization; GO:0030282 bone mineralization; GO:0048513 animal organ development; GO:0050900 leukocyte migration; GO:0042221 response to chemical; GO:0090304 nucleic acid metabolic process; GO:0001701 in utero embryonic development; GO:0044260 cellular macromolecule metabolic process; GO:1902850 microtubule cytoskeleton organization involved in mitosis; GO:0042330 taxis; GO:0040011 locomotion; GO:0048856 anatomical structure development; GO:0001832 blastocyst growth; GO:0001501 skeletal system development; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0016477 cell migration; GO:0006725 cellular aromatic compound metabolic process; GO:0048285 organelle fission; GO:0007051 spindle organization; GO:0060326 cell chemotaxis; GO:0050896 response to stimulus; GO:1903047 mitotic cell cycle process; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0070925 organelle assembly; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0031214 biomineral tissue development; GO:0007052 mitotic spindle organization; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0034622 cellular macromolecular complex assembly; GO:0048731 system development; GO:0009792 embryo development ending in birth or egg hatching; GO:0001824 blastocyst development; GO:0006807 nitrogen compound metabolic process; GO:0008283 cell proliferation; GO:0002376 immune system process; GO:0044238 primary metabolic process; GO:0007017 microtubule-based process; GO:0048534 hematopoietic or lymphoid organ development; GO:0042255 ribosome assembly; GO:0043933 macromolecular complex subunit organization; GO:0060348 bone development; GO:0030595 leukocyte chemotaxis; GO:0044767 single-organism developmental process; GO:0006996 organelle organization; GO:0000280 nuclear division; GO:0006928 movement of cell or subcellular component; GO:0010467 gene expression; GO:0022402 cell cycle process; GO:0048589 developmental growth; GO:0051179 localization; GO:0040007 growth; GO:0034660 ncRNA metabolic process; GO:0007049 cell cycle; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0000922 spindle pole; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0005623 cell; GO:0005819 spindle; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005856 cytoskeleton; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0043022 ribosome binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0008092 cytoskeletal protein binding; GO:0008017 microtubule binding; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0003676 nucleic acid binding; GO:0015631 tubulin binding; GO:0005515 protein binding; GO:0043021 ribonucleoprotein complex binding; GO:0019843 rRNA binding; ","K14574","SDO1; ribosome maturation protein SDO1","hsa03008 Ribosome biogenesis in eukaryotes - Homo sapiens (human); ","IPR018978; IPR019783; ","\"Ribosome maturation protein SBDS, C-terminal; Ribosome maturation protein SBDS, N-terminal; \"\r"]
["Q9Y3B3","Transmembrane emp24 domain-containing protein 7 OS=Homo sapiens OX=9606 GN=TMED7","TMED7",25.171,20.322,28.1,6,7,6,1.084,1.048,0.993,0.906,0.974,0.967,0.911,0.0537,"mitochondria\r","GO:0046907 intracellular transport; GO:0016192 vesicle-mediated transport; GO:0048193 Golgi vesicle transport; GO:0071702 organic substance transport; GO:0015031 protein transport; GO:0051641 cellular localization; GO:0051234 establishment of localization; GO:0006810 transport; GO:0045184 establishment of protein localization; GO:0051649 establishment of localization in cell; GO:0006890 retrograde vesicle-mediated transport, Golgi to ER; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0051179 localization; GO:0006888 ER to Golgi vesicle-mediated transport; ","GO:0030658 transport vesicle membrane; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0098796 membrane protein complex; GO:0030137 COPI-coated vesicle; GO:0030660 Golgi-associated vesicle membrane; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0030120 vesicle coat; GO:0030663 COPI-coated vesicle membrane; GO:0005623 cell; GO:0030662 coated vesicle membrane; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0030126 COPI vesicle coat; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0044431 Golgi apparatus part; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0012507 ER to Golgi transport vesicle membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0048475 coated membrane; GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0030134 ER to Golgi transport vesicle; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0030135 coated vesicle; GO:0005798 Golgi-associated vesicle; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044432 endoplasmic reticulum part; GO:0005793 endoplasmic reticulum-Golgi intermediate compartment; GO:0030117 membrane coat; GO:0030127 COPII vesicle coat; GO:0030133 transport vesicle; GO:0043234 protein complex; GO:0005794 Golgi apparatus; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ",null,"K20349",null,null,"IPR009038; ","GOLD domain; \r"]
["Q9Y3B4","Splicing factor 3B subunit 6 OS=Homo sapiens OX=9606 GN=SF3B6","SF3B6",14.585,24.817,27.2,3,4,3,0.878,0.901,0.958,1.078,1.098,1.077,1.189,0.00286,"nucleus\r","GO:0044707 single-multicellular organism process; GO:0006725 cellular aromatic compound metabolic process; GO:0043009 chordate embryonic development; GO:0044699 single-organism process; GO:0001825 blastocyst formation; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0009653 anatomical structure morphogenesis; GO:0000398 mRNA splicing, via spliceosome; GO:0008152 metabolic process; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0043170 macromolecule metabolic process; GO:0009790 embryo development; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0006396 RNA processing; GO:0032502 developmental process; GO:0009792 embryo development ending in birth or egg hatching; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0001824 blastocyst development; GO:0044238 primary metabolic process; GO:0032501 multicellular organismal process; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:0090304 nucleic acid metabolic process; GO:0001701 in utero embryonic development; GO:0044767 single-organism developmental process; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0048856 anatomical structure development; GO:0016071 mRNA metabolic process; ","GO:0043229 intracellular organelle; GO:0005686 U2 snRNP; GO:0044446 intracellular organelle part; GO:0005684 U2-type spliceosomal complex; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005681 spliceosomal complex; GO:0005623 cell; GO:0071011 precatalytic spliceosome; GO:0044422 organelle part; GO:0097525 spliceosomal snRNP complex; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0071013 catalytic step 2 spliceosome; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0030532 small nuclear ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0005689 U12-type spliceosomal complex; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:1901265 nucleoside phosphate binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0000166 nucleotide binding; GO:0036094 small molecule binding; ","K12833","SF3B14; pre-mRNA branch site protein p14","hsa03040 Spliceosome - Homo sapiens (human); ","IPR000504; IPR012677; IPR034150; ","\"RNA recognition motif domain; Nucleotide-binding alpha-beta plait domain; SF3B14, RNA recognition motif; \"\r"]
["Q9Y3B7","39S ribosomal protein L11, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL11","MRPL11",20.683,4.2811,8.3,2,2,2,0.876,0.873,0.968,1.107,1.2,0.971,1.206,0.0582,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:0016043 cellular component organization; GO:0022613 ribonucleoprotein complex biogenesis; GO:0006518 peptide metabolic process; GO:0022618 ribonucleoprotein complex assembly; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:0042273 ribosomal large subunit biogenesis; GO:0043241 protein complex disassembly; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0000027 ribosomal large subunit assembly; GO:0071826 ribonucleoprotein complex subunit organization; GO:0022607 cellular component assembly; GO:0070925 organelle assembly; GO:0065003 macromolecular complex assembly; GO:0043624 cellular protein complex disassembly; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006412 translation; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0034622 cellular macromolecular complex assembly; GO:0071822 protein complex subunit organization; GO:0006414 translational elongation; GO:0043043 peptide biosynthetic process; GO:0044763 single-organism cellular process; GO:0032984 macromolecular complex disassembly; GO:0042254 ribosome biogenesis; GO:0006807 nitrogen compound metabolic process; GO:0032543 mitochondrial translation; GO:0043603 cellular amide metabolic process; GO:0070126 mitochondrial translational termination; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0042255 ribosome assembly; GO:0006415 translational termination; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006996 organelle organization; GO:0070125 mitochondrial translational elongation; GO:0044260 cellular macromolecule metabolic process; GO:0022411 cellular component disassembly; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:1901564 organonitrogen compound metabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005762 mitochondrial large ribosomal subunit; GO:0005623 cell; GO:0000313 organellar ribosome; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044391 ribosomal subunit; GO:0005622 intracellular; GO:0044464 cell part; GO:0019866 organelle inner membrane; GO:0000315 organellar large ribosomal subunit; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005840 ribosome; GO:0005759 mitochondrial matrix; GO:0044429 mitochondrial part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005761 mitochondrial ribosome; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0015934 large ribosomal subunit; GO:0031975 envelope; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0005198 structural molecule activity; GO:0003735 structural constituent of ribosome; GO:0019843 rRNA binding; ","K02867","RP-L11; large subunit ribosomal protein L11","hsa03010 Ribosome - Homo sapiens (human); ","IPR020783; IPR020784; ","\"Ribosomal protein L11, C-terminal; Ribosomal protein L11, N-terminal; \"\r"]
["Q9Y3B8","Oligoribonuclease, mitochondrial OS=Homo sapiens OX=9606 GN=REXO2","REXO2",26.832,10.729,11,3,3,3,0.963,0.994,1.04,1.018,0.953,1.039,1.004,0.91,"cytoplasm\r","GO:0006725 cellular aromatic compound metabolic process; GO:0009117 nucleotide metabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0090304 nucleic acid metabolic process; GO:0046483 heterocycle metabolic process; GO:0006793 phosphorus metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0019637 organophosphate metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0090305 nucleic acid phosphodiester bond hydrolysis; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0030054 cell junction; GO:0031967 organelle envelope; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005730 nucleolus; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0031970 organelle envelope lumen; GO:0005925 focal adhesion; GO:0070013 intracellular organelle lumen; GO:0005758 mitochondrial intermembrane space; GO:0044464 cell part; GO:0005622 intracellular; GO:0031975 envelope; GO:0005912 adherens junction; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0004518 nuclease activity; GO:0016788 hydrolase activity, acting on ester bonds; GO:0008408 3'-5' exonuclease activity; GO:0004527 exonuclease activity; GO:0016787 hydrolase activity; ","K13288","orn; oligoribonuclease [EC:3.1.-.-]","hsa03008 Ribosome biogenesis in eukaryotes - Homo sapiens (human); ","IPR012337; IPR013520; ","\"Ribonuclease H-like domain; Exonuclease, RNase T/DNA polymerase III; \"\r"]
["Q9Y3C0","WASH complex subunit 3 OS=Homo sapiens OX=9606 GN=WASHC3","WASHC3",21.172,9.1391,11.3,2,2,2,0.908,0.939,0.967,1.108,1.037,1.042,1.133,0.0114,"cytoskeleton\r","GO:0045184 establishment of protein localization; GO:0006810 transport; GO:0071702 organic substance transport; GO:0051179 localization; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0015031 protein transport; GO:0051234 establishment of localization; ","GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0031410 cytoplasmic vesicle; GO:0071203 WASH complex; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0005769 early endosome; GO:0043226 organelle; GO:0005622 intracellular; GO:0044464 cell part; GO:0005768 endosome; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ","K18463","CCDC53; WASH complex subunit CCDC53","hsa04144 Endocytosis - Homo sapiens (human); "]
["Q9Y3C6","Peptidyl-prolyl cis-trans isomerase-like 1 OS=Homo sapiens OX=9606 GN=PPIL1","PPIL1",18.237,9.2668,16.3,2,2,2,0.939,0.915,0.955,1.012,1.058,1.117,1.135,0.0157,"cytoplasm\r","GO:0006725 cellular aromatic compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0006457 protein folding; GO:0000398 mRNA splicing, via spliceosome; GO:0008152 metabolic process; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0034641 cellular nitrogen compound metabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0006396 RNA processing; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0044238 primary metabolic process; GO:0018208 peptidyl-proline modification; GO:0000413 protein peptidyl-prolyl isomerization; GO:0016070 RNA metabolic process; GO:0006397 mRNA processing; GO:0018193 peptidyl-amino acid modification; GO:0090304 nucleic acid metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0006464 cellular protein modification process; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:0016071 mRNA metabolic process; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005681 spliceosomal complex; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:1902494 catalytic complex; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0071013 catalytic step 2 spliceosome; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0003755 peptidyl-prolyl cis-trans isomerase activity; GO:0005515 protein binding; GO:0016853 isomerase activity; GO:0003824 catalytic activity; GO:0016859 cis-trans isomerase activity; GO:0005488 binding; ","K12733","PPIL1; peptidyl-prolyl cis-trans isomerase-like 1 [EC:5.2.1.8]","hsa03040 Spliceosome - Homo sapiens (human); ","IPR002130; IPR029000; ","Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain; Cyclophilin-like domain; \r"]
["Q9Y3C8","Ubiquitin-fold modifier-conjugating enzyme 1 OS=Homo sapiens OX=9606 GN=UFC1","UFC1",19.458,9.8252,25.7,5,5,5,0.89,1.074,0.986,0.983,1.046,1.027,1.036,0.545,"cytoplasm\r","GO:0033554 cellular response to stress; GO:0051716 cellular response to stimulus; GO:0034976 response to endoplasmic reticulum stress; GO:0006950 response to stress; GO:0044267 cellular protein metabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0050896 response to stimulus; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:1990592 protein K69-linked ufmylation; GO:0008152 metabolic process; GO:0032446 protein modification by small protein conjugation; GO:0071569 protein ufmylation; GO:1990564 protein polyufmylation; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0036211 protein modification process; GO:0043412 macromolecule modification; GO:0009987 cellular process; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:0005515 protein binding; GO:0071568 UFM1 transferase activity; GO:0019787 ubiquitin-like protein transferase activity; GO:0003824 catalytic activity; GO:0016740 transferase activity; GO:0005488 binding; ","K12165",null,null,"IPR016135; ","Ubiquitin-conjugating enzyme/RWD-like; \r"]
["Q9Y3D7","Mitochondrial import inner membrane translocase subunit TIM16 OS=Homo sapiens OX=9606 GN=PAM16","PAM16",13.825,41.971,32,3,3,3,0.955,0.952,0.98,1.056,1.009,1.052,1.08,0.0113,"extracellular\r","GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0072594 establishment of protein localization to organelle; GO:0017038 protein import; GO:0006839 mitochondrial transport; GO:0044699 single-organism process; GO:0015031 protein transport; GO:0051346 negative regulation of hydrolase activity; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0032780 negative regulation of ATPase activity; GO:0051649 establishment of localization in cell; GO:1902578 single-organism localization; GO:1990542 mitochondrial transmembrane transport; GO:0007005 mitochondrion organization; GO:0065002 intracellular protein transmembrane transport; GO:0006886 intracellular protein transport; GO:0006626 protein targeting to mitochondrion; GO:1902580 single-organism cellular localization; GO:0033365 protein localization to organelle; GO:0044743 protein transmembrane import into intracellular organelle; GO:0034613 cellular protein localization; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0009987 cellular process; GO:0044765 single-organism transport; GO:0030150 protein import into mitochondrial matrix; GO:0001503 ossification; GO:0071806 protein transmembrane transport; GO:0071702 organic substance transport; GO:0070585 protein localization to mitochondrion; GO:0043086 negative regulation of catalytic activity; GO:0032501 multicellular organismal process; GO:1902582 single-organism intracellular transport; GO:0051641 cellular localization; GO:0006810 transport; GO:0045184 establishment of protein localization; GO:0055085 transmembrane transport; GO:0070727 cellular macromolecule localization; GO:0051336 regulation of hydrolase activity; GO:0043462 regulation of ATPase activity; GO:0006996 organelle organization; GO:0050790 regulation of catalytic activity; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0051179 localization; GO:0072655 establishment of protein localization to mitochondrion; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0098800 inner mitochondrial membrane protein complex; GO:0019898 extrinsic component of membrane; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0005744 mitochondrial inner membrane presequence translocase complex; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005759 mitochondrial matrix; GO:0044429 mitochondrial part; GO:0031314 extrinsic component of mitochondrial inner membrane; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031975 envelope; GO:0001405 presequence translocase-associated import motor; GO:0031312 extrinsic component of organelle membrane; GO:0043234 protein complex; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ","K17805"]
["Q9Y3D9","28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23","MRPS23",21.77,2.9426,5.3,1,3,1,1.056,0.97,0.945,0.969,1.06,1.006,1.022,0.635,"mitochondria\r","GO:0016043 cellular component organization; GO:0006518 peptide metabolic process; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0044237 cellular metabolic process; GO:0043241 protein complex disassembly; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0043624 cellular protein complex disassembly; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006412 translation; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0071822 protein complex subunit organization; GO:0006414 translational elongation; GO:0043043 peptide biosynthetic process; GO:0044763 single-organism cellular process; GO:0032984 macromolecular complex disassembly; GO:0006807 nitrogen compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0032543 mitochondrial translation; GO:0070126 mitochondrial translational termination; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:0006415 translational termination; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0070125 mitochondrial translational elongation; GO:0044260 cellular macromolecule metabolic process; GO:0022411 cellular component disassembly; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0071840 cellular component organization or biogenesis; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005740 mitochondrial envelope; GO:0005856 cytoskeleton; GO:0031965 nuclear membrane; GO:0005622 intracellular; GO:0044464 cell part; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0043229 intracellular organelle; GO:0005840 ribosome; GO:0044429 mitochondrial part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0005635 nuclear envelope; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0045111 intermediate filament cytoskeleton; GO:0031975 envelope; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0005198 structural molecule activity; GO:0003735 structural constituent of ribosome; ","K17402",null,null,"IPR023611; ","\"Ribosomal protein S23/S25, mitochondrial; \"\r"]
["Q9Y3E1","Hepatoma-derived growth factor-related protein 3 OS=Homo sapiens OX=9606 GN=HDGFL3","HDGFL3",22.619,7.5959,15.8,3,4,2,1.003,1.067,1.196,0.973,0.84,0.939,0.843,0.0661,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0031111 negative regulation of microtubule polymerization or depolymerization; GO:0031109 microtubule polymerization or depolymerization; GO:0048666 neuron development; GO:0048869 cellular developmental process; GO:0051129 negative regulation of cellular component organization; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0031110 regulation of microtubule polymerization or depolymerization; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0051493 regulation of cytoskeleton organization; GO:0032502 developmental process; GO:0007399 nervous system development; GO:0071822 protein complex subunit organization; GO:0048699 generation of neurons; GO:0051494 negative regulation of cytoskeleton organization; GO:0044763 single-organism cellular process; GO:0007026 negative regulation of microtubule depolymerization; GO:0032501 multicellular organismal process; GO:0031114 regulation of microtubule depolymerization; GO:0032886 regulation of microtubule-based process; GO:0010639 negative regulation of organelle organization; GO:0000226 microtubule cytoskeleton organization; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0030030 cell projection organization; GO:0043242 negative regulation of protein complex disassembly; GO:1902904 negative regulation of supramolecular fiber organization; GO:0051258 protein polymerization; GO:0043244 regulation of protein complex disassembly; GO:0070271 protein complex biogenesis; GO:0046785 microtubule polymerization; GO:0048856 anatomical structure development; GO:0097435 supramolecular fiber organization; GO:1902903 regulation of supramolecular fiber organization; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0048468 cell development; GO:1901880 negative regulation of protein depolymerization; GO:0030154 cell differentiation; GO:0007275 multicellular organism development; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0043623 cellular protein complex assembly; GO:0070507 regulation of microtubule cytoskeleton organization; GO:0034622 cellular macromolecular complex assembly; GO:0048731 system development; GO:1901879 regulation of protein depolymerization; GO:0033043 regulation of organelle organization; GO:0008283 cell proliferation; GO:0031175 neuron projection development; GO:0007017 microtubule-based process; GO:0043933 macromolecular complex subunit organization; GO:0030182 neuron differentiation; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0051128 regulation of cellular component organization; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0008083 growth factor activity; GO:0008092 cytoskeletal protein binding; GO:0005102 receptor binding; GO:0008017 microtubule binding; GO:0005488 binding; GO:0015631 tubulin binding; GO:0005515 protein binding; ",{"$nulls":3},"IPR000313; ","PWWP domain; \r"]
["Q9Y3E5","Peptidyl-tRNA hydrolase 2, mitochondrial OS=Homo sapiens OX=9606 GN=PTRH2","PTRH2",19.193,22.761,20.1,3,4,3,0.838,0.925,0.972,1.031,1.156,1.071,1.191,0.0332,"extracellular\r","GO:0050794 regulation of cellular process; GO:0010941 regulation of cell death; GO:0043069 negative regulation of programmed cell death; GO:0060255 regulation of macromolecule metabolic process; GO:0043067 regulation of programmed cell death; GO:0044699 single-organism process; GO:2000209 regulation of anoikis; GO:0043065 positive regulation of apoptotic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0043066 negative regulation of apoptotic process; GO:0006915 apoptotic process; GO:0009987 cellular process; GO:0010468 regulation of gene expression; GO:0010629 negative regulation of gene expression; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0048518 positive regulation of biological process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0009892 negative regulation of metabolic process; GO:0010942 positive regulation of cell death; GO:2000210 positive regulation of anoikis; GO:0050789 regulation of biological process; GO:0008219 cell death; GO:2000811 negative regulation of anoikis; GO:0019222 regulation of metabolic process; GO:0012501 programmed cell death; GO:0060548 negative regulation of cell death; GO:0042981 regulation of apoptotic process; GO:0043068 positive regulation of programmed cell death; GO:0065007 biological regulation; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005829 cytosol; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0052689 carboxylic ester hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0004045 aminoacyl-tRNA hydrolase activity; GO:0016788 hydrolase activity, acting on ester bonds; ","K04794",null,null,"IPR023476; ","Peptidyl-tRNA hydrolase II domain; \r"]
["Q9Y3F4","Serine-threonine kinase receptor-associated protein OS=Homo sapiens OX=9606 GN=STRAP","STRAP",38.438,38.486,22,7,10,7,0.911,0.964,0.939,1.061,1.022,1.061,1.117,0.0057,"mitochondria\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0065008 regulation of biological quality; GO:0010717 regulation of epithelial to mesenchymal transition; GO:0007586 digestion; GO:0022618 ribonucleoprotein complex assembly; GO:1903845 negative regulation of cellular response to transforming growth factor beta stimulus; GO:0044237 cellular metabolic process; GO:0008285 negative regulation of cell proliferation; GO:0008152 metabolic process; GO:0010719 negative regulation of epithelial to mesenchymal transition; GO:0065003 macromolecular complex assembly; GO:0050678 regulation of epithelial cell proliferation; GO:0032879 regulation of localization; GO:0043170 macromolecule metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:0006396 RNA processing; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0010632 regulation of epithelial cell migration; GO:0080090 regulation of primary metabolic process; GO:0000122 negative regulation of transcription from RNA polymerase II promoter; GO:0090287 regulation of cellular response to growth factor stimulus; GO:0031323 regulation of cellular metabolic process; GO:2000146 negative regulation of cell motility; GO:0032501 multicellular organismal process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0032269 negative regulation of cellular protein metabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0016071 mRNA metabolic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0042127 regulation of cell proliferation; GO:0031399 regulation of protein modification process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0060249 anatomical structure homeostasis; GO:0051239 regulation of multicellular organismal process; GO:0045892 negative regulation of transcription, DNA-templated; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0023057 negative regulation of signaling; GO:0046483 heterocycle metabolic process; GO:0010648 negative regulation of cell communication; GO:0006139 nucleobase-containing compound metabolic process; GO:2000145 regulation of cell motility; GO:0009889 regulation of biosynthetic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0051171 regulation of nitrogen compound metabolic process; GO:0001933 negative regulation of protein phosphorylation; GO:0008380 RNA splicing; GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation; GO:0009966 regulation of signal transduction; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0051270 regulation of cellular component movement; GO:0030334 regulation of cell migration; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0009890 negative regulation of biosynthetic process; GO:0030336 negative regulation of cell migration; GO:0050793 regulation of developmental process; GO:0045936 negative regulation of phosphate metabolic process; GO:0000387 spliceosomal snRNP assembly; GO:0051093 negative regulation of developmental process; GO:0009968 negative regulation of signal transduction; GO:0010633 negative regulation of epithelial cell migration; GO:0023051 regulation of signaling; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0051253 negative regulation of RNA metabolic process; GO:0048871 multicellular organismal homeostasis; GO:0031400 negative regulation of protein modification process; GO:0030277 maintenance of gastrointestinal epithelium; GO:0040013 negative regulation of locomotion; GO:2001141 regulation of RNA biosynthetic process; GO:0010646 regulation of cell communication; GO:0071826 ribonucleoprotein complex subunit organization; GO:0022607 cellular component assembly; GO:0045596 negative regulation of cell differentiation; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0090304 nucleic acid metabolic process; GO:1902679 negative regulation of RNA biosynthetic process; GO:0001894 tissue homeostasis; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0050680 negative regulation of epithelial cell proliferation; GO:0051271 negative regulation of cellular component movement; GO:2000026 regulation of multicellular organismal development; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0017015 regulation of transforming growth factor beta receptor signaling pathway; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031324 negative regulation of cellular metabolic process; GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0071704 organic substance metabolic process; GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0042592 homeostatic process; GO:0000398 mRNA splicing, via spliceosome; GO:0060393 regulation of pathway-restricted SMAD protein phosphorylation; GO:0042326 negative regulation of phosphorylation; GO:0090288 negative regulation of cellular response to growth factor stimulus; GO:0034641 cellular nitrogen compound metabolic process; GO:0010669 epithelial structure maintenance; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0034622 cellular macromolecular complex assembly; GO:0006355 regulation of transcription, DNA-templated; GO:0003008 system process; GO:0010629 negative regulation of gene expression; GO:0001932 regulation of protein phosphorylation; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway; GO:0048585 negative regulation of response to stimulus; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0043933 macromolecular complex subunit organization; GO:1903844 regulation of cellular response to transforming growth factor beta stimulus; GO:0051246 regulation of protein metabolic process; GO:0022600 digestive system process; GO:0010563 negative regulation of phosphorus metabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0010467 gene expression; GO:0031327 negative regulation of cellular biosynthetic process; GO:0040012 regulation of locomotion; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0032797 SMN complex; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005654 nucleoplasm; GO:0034719 SMN-Sm protein complex; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0043234 protein complex; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005515 protein binding; GO:0005102 receptor binding; GO:0005488 binding; GO:0003676 nucleic acid binding; ","K13137","STRAP; serine-threonine kinase receptor-associated protein","hsa03013 RNA transport - Homo sapiens (human); ","IPR017986; IPR015943; ","WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain; \r"]
["Q9Y3I0","tRNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB","RTCB",55.21,86.22,28.7,12,19,12,0.951,0.948,1.027,1.043,1.044,0.995,1.053,0.162,"cytoplasm\r","GO:0000003 reproduction; GO:0044707 single-multicellular organism process; GO:0006725 cellular aromatic compound metabolic process; GO:0001890 placenta development; GO:0022414 reproductive process; GO:0043009 chordate embryonic development; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0044702 single organism reproductive process; GO:0034641 cellular nitrogen compound metabolic process; GO:0007275 multicellular organism development; GO:0043170 macromolecule metabolic process; GO:0009790 embryo development; GO:0061458 reproductive system development; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0034470 ncRNA processing; GO:0006396 RNA processing; GO:0032502 developmental process; GO:0003006 developmental process involved in reproduction; GO:0048731 system development; GO:0009792 embryo development ending in birth or egg hatching; GO:0048608 reproductive structure development; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0044238 primary metabolic process; GO:0032501 multicellular organismal process; GO:0016070 RNA metabolic process; GO:0000394 RNA splicing, via endonucleolytic cleavage and ligation; GO:0048513 animal organ development; GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation; GO:0006399 tRNA metabolic process; GO:0090304 nucleic acid metabolic process; GO:0001701 in utero embryonic development; GO:0044767 single-organism developmental process; GO:0008033 tRNA processing; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0034660 ncRNA metabolic process; GO:0048856 anatomical structure development; ","GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0072669 tRNA-splicing ligase complex; GO:0070013 intracellular organelle lumen; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005635 nuclear envelope; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0044432 endoplasmic reticulum part; GO:0031975 envelope; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0016874 ligase activity; GO:0005515 protein binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0008092 cytoskeletal protein binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0003972 RNA ligase (ATP) activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003723 RNA binding; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0016886 ligase activity, forming phosphoric ester bonds; GO:0000166 nucleotide binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0017166 vinculin binding; GO:0003676 nucleic acid binding; GO:0046872 metal ion binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; GO:0008452 RNA ligase activity; ","K14415"]
["Q9Y3I1","F-box only protein 7 OS=Homo sapiens OX=9606 GN=FBXO7","FBXO7",58.502,24.075,4.6,2,4,2,1.035,0.922,0.928,1.013,0.981,1.135,1.085,0.237,"nucleus\r","GO:0002694 regulation of leukocyte activation; GO:0065008 regulation of biological quality; GO:1902807 negative regulation of cell cycle G1/S phase transition; GO:0010941 regulation of cell death; GO:0006914 autophagy; GO:0010564 regulation of cell cycle process; GO:0010821 regulation of mitochondrion organization; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0071900 regulation of protein serine/threonine kinase activity; GO:0008152 metabolic process; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0033365 protein localization to organelle; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0008104 protein localization; GO:1901032 negative regulation of response to reactive oxygen species; GO:1903203 regulation of oxidative stress-induced neuron death; GO:0007399 nervous system development; GO:0042325 regulation of phosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:1903599 positive regulation of mitophagy; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0031329 regulation of cellular catabolic process; GO:2000134 negative regulation of G1/S transition of mitotic cell cycle; GO:0009894 regulation of catabolic process; GO:0044763 single-organism cellular process; GO:0031323 regulation of cellular metabolic process; GO:0043086 negative regulation of catalytic activity; GO:0032501 multicellular organismal process; GO:0010506 regulation of autophagy; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0010948 negative regulation of cell cycle process; GO:1903205 regulation of hydrogen peroxide-induced cell death; GO:0080135 regulation of cellular response to stress; GO:0030163 protein catabolic process; GO:0010508 positive regulation of autophagy; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:1903202 negative regulation of oxidative stress-induced cell death; GO:0044260 cellular macromolecule metabolic process; GO:0002682 regulation of immune system process; GO:0006464 cellular protein modification process; GO:0072655 establishment of protein localization to mitochondrion; GO:0060548 negative regulation of cell death; GO:0010975 regulation of neuron projection development; GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0046907 intracellular transport; GO:0007346 regulation of mitotic cell cycle; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:1904029 regulation of cyclin-dependent protein kinase activity; GO:0051239 regulation of multicellular organismal process; GO:1903706 regulation of hemopoiesis; GO:0000209 protein polyubiquitination; GO:0050866 negative regulation of cell activation; GO:1901987 regulation of cell cycle phase transition; GO:0009896 positive regulation of catabolic process; GO:0051338 regulation of transferase activity; GO:0006626 protein targeting to mitochondrion; GO:0044248 cellular catabolic process; GO:0001933 negative regulation of protein phosphorylation; GO:0007275 multicellular organism development; GO:0034613 cellular protein localization; GO:1901215 negative regulation of neuron death; GO:0016567 protein ubiquitination; GO:0048731 system development; GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0051960 regulation of nervous system development; GO:0060284 regulation of cell development; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1900408 negative regulation of cellular response to oxidative stress; GO:0045184 establishment of protein localization; GO:1902106 negative regulation of leukocyte differentiation; GO:0032446 protein modification by small protein conjugation; GO:1903207 regulation of hydrogen peroxide-induced neuron death; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0031647 regulation of protein stability; GO:1902882 regulation of response to oxidative stress; GO:0051179 localization; GO:0043412 macromolecule modification; GO:0050793 regulation of developmental process; GO:0045936 negative regulation of phosphate metabolic process; GO:2000045 regulation of G1/S transition of mitotic cell cycle; GO:0051093 negative regulation of developmental process; GO:0072594 establishment of protein localization to organelle; GO:0048869 cellular developmental process; GO:0000422 mitophagy; GO:0006839 mitochondrial transport; GO:0031331 positive regulation of cellular catabolic process; GO:0022008 neurogenesis; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:1903008 organelle disassembly; GO:0051249 regulation of lymphocyte activation; GO:0031400 negative regulation of protein modification process; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0051130 positive regulation of cellular component organization; GO:0045930 negative regulation of mitotic cell cycle; GO:1903204 negative regulation of oxidative stress-induced neuron death; GO:0051649 establishment of localization in cell; GO:0071901 negative regulation of protein serine/threonine kinase activity; GO:1901991 negative regulation of mitotic cell cycle phase transition; GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity; GO:0009893 positive regulation of metabolic process; GO:0033673 negative regulation of kinase activity; GO:1902806 regulation of cell cycle G1/S phase transition; GO:0007005 mitochondrion organization; GO:0002695 negative regulation of leukocyte activation; GO:0045596 negative regulation of cell differentiation; GO:0033036 macromolecule localization; GO:0051726 regulation of cell cycle; GO:0032502 developmental process; GO:0048522 positive regulation of cellular process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0051348 negative regulation of transferase activity; GO:0010605 negative regulation of macromolecule metabolic process; GO:0002683 negative regulation of immune system process; GO:1902589 single-organism organelle organization; GO:0050865 regulation of cell activation; GO:0050789 regulation of biological process; GO:1904030 negative regulation of cyclin-dependent protein kinase activity; GO:0032268 regulation of cellular protein metabolic process; GO:1902883 negative regulation of response to oxidative stress; GO:0045664 regulation of neuron differentiation; GO:0010638 positive regulation of organelle organization; GO:1902105 regulation of leukocyte differentiation; GO:0045620 negative regulation of lymphocyte differentiation; GO:1903206 negative regulation of hydrogen peroxide-induced cell death; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0006469 negative regulation of protein kinase activity; GO:0044092 negative regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0043549 regulation of kinase activity; GO:2000026 regulation of multicellular organismal development; GO:0045859 regulation of protein kinase activity; GO:0016043 cellular component organization; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0045786 negative regulation of cell cycle; GO:0044257 cellular protein catabolic process; GO:0051250 negative regulation of lymphocyte activation; GO:1901988 negative regulation of cell cycle phase transition; GO:0060255 regulation of macromolecule metabolic process; GO:0031344 regulation of cell projection organization; GO:1903201 regulation of oxidative stress-induced cell death; GO:0031324 negative regulation of cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0042326 negative regulation of phosphorylation; GO:0006886 intracellular protein transport; GO:1903707 negative regulation of hemopoiesis; GO:0006508 proteolysis; GO:0009987 cellular process; GO:1901214 regulation of neuron death; GO:0045595 regulation of cell differentiation; GO:0043632 modification-dependent macromolecule catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0019941 modification-dependent protein catabolic process; GO:0044712 single-organism catabolic process; GO:0001932 regulation of protein phosphorylation; GO:0033043 regulation of organelle organization; GO:0048585 negative regulation of response to stimulus; GO:0070585 protein localization to mitochondrion; GO:0048518 positive regulation of biological process; GO:0045619 regulation of lymphocyte differentiation; GO:0051641 cellular localization; GO:0010822 positive regulation of mitochondrion organization; GO:0070727 cellular macromolecule localization; GO:0061726 mitochondrion disassembly; GO:1900407 regulation of cellular response to oxidative stress; GO:1903146 regulation of mitophagy; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0009057 macromolecule catabolic process; GO:0010563 negative regulation of phosphorus metabolic process; GO:0022411 cellular component disassembly; GO:0051248 negative regulation of protein metabolic process; GO:1903208 negative regulation of hydrogen peroxide-induced neuron death; GO:0051128 regulation of cellular component organization; GO:0040012 regulation of locomotion; GO:1901031 regulation of response to reactive oxygen species; GO:0009056 catabolic process; GO:0050767 regulation of neurogenesis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0097409 glial cytoplasmic inclusion; GO:0016234 inclusion body; GO:0005737 cytoplasm; GO:0019005 SCF ubiquitin ligase complex; GO:0031461 cullin-RING ubiquitin ligase complex; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:1990234 transferase complex; GO:0005829 cytosol; GO:0005623 cell; GO:0097414 classical Lewy body; GO:0097462 Lewy neurite; GO:0005739 mitochondrion; GO:1990038 Lewy body corona; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:1902494 catalytic complex; GO:0005622 intracellular; GO:0044464 cell part; GO:0097413 Lewy body; GO:0043005 neuron projection; GO:1990037 Lewy body core; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0000151 ubiquitin ligase complex; GO:0097458 neuron part; GO:0044444 cytoplasmic part; ","GO:0019787 ubiquitin-like protein transferase activity; GO:0046982 protein heterodimerization activity; GO:0031625 ubiquitin protein ligase binding; GO:0046983 protein dimerization activity; GO:0019901 protein kinase binding; GO:0005515 protein binding; GO:0019900 kinase binding; GO:0032182 ubiquitin-like protein binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0004842 ubiquitin-protein transferase activity; GO:0043130 ubiquitin binding; GO:0044389 ubiquitin-like protein ligase binding; GO:0016740 transferase activity; GO:0019899 enzyme binding; ","K10293",null,null,"IPR001810; IPR021625; IPR029071; ","\"F-box domain; PI31 proteasome regulator,  N-terminal; Ubiquitin-related domain; \"\r"]
["Q9Y3L3","SH3 domain-binding protein 1 OS=Homo sapiens OX=9606 GN=SH3BP1","SH3BP1",75.712,31.804,12.4,6,6,6,0.955,0.998,0.997,1.087,1.062,0.98,1.061,0.168,"nucleus\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0051716 cellular response to stimulus; GO:0043547 positive regulation of GTPase activity; GO:0044699 single-organism process; GO:0023052 signaling; GO:0050896 response to stimulus; GO:0043085 positive regulation of catalytic activity; GO:0007165 signal transduction; GO:0050789 regulation of biological process; GO:0007154 cell communication; GO:0051336 regulation of hydrolase activity; GO:0051345 positive regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0044093 positive regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0065009 regulation of molecular function; GO:0009987 cellular process; GO:0065007 biological regulation; ","GO:0044424 intracellular part; GO:0005623 cell; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; ","GO:0030234 enzyme regulator activity; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0005488 binding; GO:0030695 GTPase regulator activity; GO:0005515 protein binding; GO:0019904 protein domain specific binding; GO:0098772 molecular function regulator; GO:0017124 SH3 domain binding; GO:0008047 enzyme activator activity; GO:0005096 GTPase activator activity; ","K20652",null,null,"IPR027267; IPR004148; IPR008936; IPR000198; ","Arfaptin homology (AH) domain/BAR domain; BAR domain; Rho GTPase activation protein; Rho GTPase-activating protein domain; \r"]
["Q9Y3L5","Ras-related protein Rap-2c OS=Homo sapiens OX=9606 GN=RAP2C","RAP2C",20.745,8.9209,20.2,3,4,2,1.048,0.855,1.003,1.028,1.014,1.054,1.065,0.347,"cytoplasm\r","GO:0044700 single organism signaling; GO:0045321 leukocyte activation; GO:0032270 positive regulation of cellular protein metabolic process; GO:0031954 positive regulation of protein autophosphorylation; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0045446 endothelial cell differentiation; GO:0051234 establishment of localization; GO:0040013 negative regulation of locomotion; GO:2001141 regulation of RNA biosynthetic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0009893 positive regulation of metabolic process; GO:0032879 regulation of localization; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0051716 cellular response to stimulus; GO:0042325 regulation of phosphorylation; GO:0002064 epithelial cell development; GO:0002443 leukocyte mediated immunity; GO:0051174 regulation of phosphorus metabolic process; GO:0009888 tissue development; GO:0045937 positive regulation of phosphate metabolic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0061097 regulation of protein tyrosine kinase activity; GO:0048522 positive regulation of cellular process; GO:0007264 small GTPase mediated signal transduction; GO:2000146 negative regulation of cell motility; GO:0023052 signaling; GO:0031323 regulation of cellular metabolic process; GO:0002444 myeloid leukocyte mediated immunity; GO:0006810 transport; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0032940 secretion by cell; GO:0050790 regulation of catalytic activity; GO:0065009 regulation of molecular function; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0043299 leukocyte degranulation; GO:0019220 regulation of phosphate metabolic process; GO:0048856 anatomical structure development; GO:0007265 Ras protein signal transduction; GO:0043549 regulation of kinase activity; GO:0051271 negative regulation of cellular component movement; GO:0030855 epithelial cell differentiation; GO:0050794 regulation of cellular process; GO:0045859 regulation of protein kinase activity; GO:0002283 neutrophil activation involved in immune response; GO:0050730 regulation of peptidyl-tyrosine phosphorylation; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0031399 regulation of protein modification process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0030154 cell differentiation; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:2000145 regulation of cell motility; GO:0009889 regulation of biosynthetic process; GO:0051338 regulation of transferase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:0036230 granulocyte activation; GO:0061028 establishment of endothelial barrier; GO:0009987 cellular process; GO:0032486 Rap protein signal transduction; GO:0051270 regulation of cellular component movement; GO:0035556 intracellular signal transduction; GO:0016192 vesicle-mediated transport; GO:0001932 regulation of protein phosphorylation; GO:0031401 positive regulation of protein modification process; GO:0030334 regulation of cell migration; GO:0010556 regulation of macromolecule biosynthetic process; GO:0002376 immune system process; GO:0031952 regulation of protein autophosphorylation; GO:0001934 positive regulation of protein phosphorylation; GO:0043312 neutrophil degranulation; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0002263 cell activation involved in immune response; GO:0003158 endothelium development; GO:0002366 leukocyte activation involved in immune response; GO:0090557 establishment of endothelial intestinal barrier; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:0051247 positive regulation of protein metabolic process; GO:0030336 negative regulation of cell migration; GO:0044767 single-organism developmental process; GO:0001885 endothelial cell development; GO:0051246 regulation of protein metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0001775 cell activation; GO:0040012 regulation of locomotion; GO:0051179 localization; GO:0006955 immune response; GO:0006887 exocytosis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0044291 cell-cell contact zone; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0055038 recycling endosome membrane; GO:0044424 intracellular part; GO:0005911 cell-cell junction; GO:0005623 cell; GO:0044422 organelle part; GO:0070821 tertiary granule membrane; GO:0055037 recycling endosome; GO:0070062 extracellular exosome; GO:0070160 occluding junction; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0098805 whole membrane; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0010008 endosome membrane; GO:0098588 bounding membrane of organelle; GO:0070820 tertiary granule; GO:0044446 intracellular organelle part; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0044440 endosomal part; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005923 bicellular tight junction; GO:0043296 apical junction complex; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0030667 secretory granule membrane; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0000166 nucleotide binding; GO:0003712 transcription cofactor activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0019003 GDP binding; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0000989 transcription factor activity, transcription factor binding; GO:0003713 transcription coactivator activity; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0000988 transcription factor activity, protein binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; ","K07839","RAP2C; Ras-related protein Rap-2C","hsa04530 Tight junction - Homo sapiens (human); ","IPR005225; IPR027417; ","Small GTP-binding protein domain; P-loop containing nucleoside triphosphate hydrolase; \r"]
["Q9Y3P9","Rab GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RABGAP1","RABGAP1",121.74,16.482,7,7,9,6,0.994,0.985,1.081,1.014,0.944,0.994,0.965,0.386,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0060627 regulation of vesicle-mediated transport; GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0044699 single-organism process; GO:0031338 regulation of vesicle fusion; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0090630 activation of GTPase activity; GO:0051649 establishment of localization in cell; GO:0051345 positive regulation of hydrolase activity; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0006886 intracellular protein transport; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0043547 positive regulation of GTPase activity; GO:0051049 regulation of transport; GO:0044763 single-organism cellular process; GO:0033043 regulation of organelle organization; GO:0071702 organic substance transport; GO:0051641 cellular localization; GO:0043085 positive regulation of catalytic activity; GO:0006810 transport; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0061024 membrane organization; GO:0065009 regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0007049 cell cycle; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005875 microtubule associated complex; GO:0005829 cytosol; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0043226 organelle; GO:0005815 microtubule organizing center; GO:0015630 microtubule cytoskeleton; GO:0005813 centrosome; GO:0005622 intracellular; GO:0044464 cell part; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0031267 small GTPase binding; GO:0003677 DNA binding; GO:0060589 nucleoside-triphosphatase regulator activity; GO:0030695 GTPase regulator activity; GO:0015631 tubulin binding; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0017137 Rab GTPase binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0008092 cytoskeletal protein binding; GO:0030234 enzyme regulator activity; GO:0017016 Ras GTPase binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0051020 GTPase binding; GO:0008047 enzyme activator activity; GO:0019899 enzyme binding; GO:0005096 GTPase activator activity; ","K20284",null,null,"IPR009057; IPR011993; IPR000195; IPR022164; IPR006020; ","Homeobox domain-like; PH domain-like; Rab-GTPase-TBC domain; Kinesin-like; PTB/PI domain; \r"]
["Q9Y3Q8","TSC22 domain family protein 4 OS=Homo sapiens OX=9606 GN=TSC22D4","TSC22D4",41.026,4.2119,4.6,2,3,2,1.067,1.013,1.078,0.911,1.03,0.921,0.906,0.0848,"nucleus\r","GO:0065008 regulation of biological quality; GO:0010941 regulation of cell death; GO:0097659 nucleic acid-templated transcription; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0051253 negative regulation of RNA metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0043170 macromolecule metabolic process; GO:0010558 negative regulation of macromolecule biosynthetic process; GO:1903507 negative regulation of nucleic acid-templated transcription; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0070229 negative regulation of lymphocyte apoptotic process; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0070233 negative regulation of T cell apoptotic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0016070 RNA metabolic process; GO:0002683 negative regulation of immune system process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:1902679 negative regulation of RNA biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0002682 regulation of immune system process; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0060548 negative regulation of cell death; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0070228 regulation of lymphocyte apoptotic process; GO:0043069 negative regulation of programmed cell death; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0043067 regulation of programmed cell death; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0048523 negative regulation of cellular process; GO:0070236 negative regulation of activation-induced cell death of T cells; GO:0032844 regulation of homeostatic process; GO:0071704 organic substance metabolic process; GO:0045892 negative regulation of transcription, DNA-templated; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0043066 negative regulation of apoptotic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0070235 regulation of activation-induced cell death of T cells; GO:0034641 cellular nitrogen compound metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:2000113 negative regulation of cellular macromolecule biosynthetic process; GO:0070232 regulation of T cell apoptotic process; GO:0006355 regulation of transcription, DNA-templated; GO:0010629 negative regulation of gene expression; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0032845 negative regulation of homeostatic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0009892 negative regulation of metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0009890 negative regulation of biosynthetic process; GO:2000106 regulation of leukocyte apoptotic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0010467 gene expression; GO:0031327 negative regulation of cellular biosynthetic process; GO:2000107 negative regulation of leukocyte apoptotic process; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; ","GO:0005515 protein binding; GO:0003700 transcription factor activity, sequence-specific DNA binding; GO:0005488 binding; GO:0001071 nucleic acid binding transcription factor activity; "]
["Q9Y3S2","Zinc finger protein 330 OS=Homo sapiens OX=9606 GN=ZNF330","ZNF330",36.201,6.4444,8.8,3,3,3,1.115,0.981,0.999,1.053,0.971,0.898,0.944,0.395,"nucleus\r",null,"GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0030496 midbody; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005730 nucleolus; GO:0005623 cell; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0098687 chromosomal region; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0000775 chromosome, centromeric region; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0046914 transition metal ion binding; GO:0005488 binding; GO:0043167 ion binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0005515 protein binding; GO:0008270 zinc ion binding; "]
["Q9Y3U8","60S ribosomal protein L36 OS=Homo sapiens OX=9606 GN=RPL36","RPL36",12.254,18.124,37.1,5,7,5,0.943,0.966,0.799,1.117,1.114,1.043,1.209,0.039,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0072594 establishment of protein localization to organelle; GO:0006518 peptide metabolic process; GO:0009058 biosynthetic process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0008152 metabolic process; GO:0044033 multi-organism metabolic process; GO:0051649 establishment of localization in cell; GO:0002181 cytoplasmic translation; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0070972 protein localization to endoplasmic reticulum; GO:0006364 rRNA processing; GO:0006413 translational initiation; GO:1901361 organic cyclic compound catabolic process; GO:0033365 protein localization to organelle; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0044419 interspecies interaction between organisms; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0006412 translation; GO:0016072 rRNA metabolic process; GO:0006396 RNA processing; GO:0034470 ncRNA processing; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0072657 protein localization to membrane; GO:0043043 peptide biosynthetic process; GO:0042254 ribosome biogenesis; GO:1901360 organic cyclic compound metabolic process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0032774 RNA biosynthetic process; GO:0045047 protein targeting to ER; GO:0043603 cellular amide metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0006401 RNA catabolic process; GO:0016070 RNA metabolic process; GO:0019439 aromatic compound catabolic process; GO:1901575 organic substance catabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0019083 viral transcription; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0046907 intracellular transport; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019058 viral life cycle; GO:0044267 cellular protein metabolic process; GO:0006613 cotranslational protein targeting to membrane; GO:0048519 negative regulation of biological process; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0016032 viral process; GO:0019080 viral gene expression; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0006886 intracellular protein transport; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0034613 cellular protein localization; GO:0009059 macromolecule biosynthetic process; GO:0090150 establishment of protein localization to membrane; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0051179 localization; GO:0009056 catabolic process; GO:0034660 ncRNA metabolic process; GO:0071840 cellular component organization or biogenesis; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044391 ribosomal subunit; GO:0005622 intracellular; GO:0044464 cell part; GO:0044445 cytosolic part; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0022626 cytosolic ribosome; GO:0043229 intracellular organelle; GO:0005840 ribosome; GO:0043232 intracellular non-membrane-bounded organelle; GO:0022625 cytosolic large ribosomal subunit; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0015934 large ribosomal subunit; GO:1990904 ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005198 structural molecule activity; GO:0003735 structural constituent of ribosome; ","K02920","RP-L36e; large subunit ribosomal protein L36e","hsa03010 Ribosome - Homo sapiens (human); "]
["Q9Y3Z3","Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 OS=Homo sapiens OX=9606 GN=SAMHD1","SAMHD1",72.2,101.31,34,19,32,19,0.921,0.941,0.973,1.04,1.067,1.048,1.113,0.00376,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0007166 cell surface receptor signaling pathway; GO:0009117 nucleotide metabolic process; GO:0098542 defense response to other organism; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0031347 regulation of defense response; GO:0009262 deoxyribonucleotide metabolic process; GO:0044237 cellular metabolic process; GO:0071345 cellular response to cytokine stimulus; GO:0006796 phosphate-containing compound metabolic process; GO:0009607 response to biotic stimulus; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:1901292 nucleoside phosphate catabolic process; GO:0019692 deoxyribose phosphate metabolic process; GO:0007154 cell communication; GO:0045088 regulation of innate immune response; GO:0022607 cellular component assembly; GO:0051262 protein tetramerization; GO:0006195 purine nucleotide catabolic process; GO:0065003 macromolecular complex assembly; GO:0006753 nucleoside phosphate metabolic process; GO:1901361 organic cyclic compound catabolic process; GO:0044419 interspecies interaction between organisms; GO:0009217 purine deoxyribonucleoside triphosphate catabolic process; GO:0070887 cellular response to chemical stimulus; GO:0051716 cellular response to stimulus; GO:0071822 protein complex subunit organization; GO:0034097 response to cytokine; GO:0009215 purine deoxyribonucleoside triphosphate metabolic process; GO:0009166 nucleotide catabolic process; GO:0044281 small molecule metabolic process; GO:0009155 purine deoxyribonucleotide catabolic process; GO:0044763 single-organism cellular process; GO:0072521 purine-containing compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0034340 response to type I interferon; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0046070 dGTP metabolic process; GO:0023052 signaling; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0019439 aromatic compound catabolic process; GO:1901575 organic substance catabolic process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0051607 defense response to virus; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:0002682 regulation of immune system process; GO:0006952 defense response; GO:0070271 protein complex biogenesis; GO:0009204 deoxyribonucleoside triphosphate catabolic process; GO:0009615 response to virus; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0060337 type I interferon signaling pathway; GO:0046061 dATP catabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0002252 immune effector process; GO:0051260 protein homooligomerization; GO:0046434 organophosphate catabolic process; GO:0071310 cellular response to organic substance; GO:0046060 dATP metabolic process; GO:0009200 deoxyribonucleoside triphosphate metabolic process; GO:0080134 regulation of response to stress; GO:0043207 response to external biotic stimulus; GO:0072523 purine-containing compound catabolic process; GO:0050896 response to stimulus; GO:0009394 2'-deoxyribonucleotide metabolic process; GO:0051707 response to other organism; GO:0045087 innate immune response; GO:0051259 protein oligomerization; GO:0006203 dGTP catabolic process; GO:0046386 deoxyribose phosphate catabolic process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0051289 protein homotetramerization; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0016032 viral process; GO:1901135 carbohydrate derivative metabolic process; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0071357 cellular response to type I interferon; GO:0034655 nucleobase-containing compound catabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0019221 cytokine-mediated signaling pathway; GO:0009987 cellular process; GO:0009151 purine deoxyribonucleotide metabolic process; GO:0006461 protein complex assembly; GO:0006950 response to stress; GO:0044712 single-organism catabolic process; GO:0009264 deoxyribonucleotide catabolic process; GO:0006807 nitrogen compound metabolic process; GO:1901136 carbohydrate derivative catabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0006163 purine nucleotide metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0009143 nucleoside triphosphate catabolic process; GO:0009146 purine nucleoside triphosphate catabolic process; GO:1901565 organonitrogen compound catabolic process; GO:0006793 phosphorus metabolic process; GO:0019637 organophosphate metabolic process; GO:0006955 immune response; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; GO:1901564 organonitrogen compound metabolic process; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0071944 cell periphery; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0016793 triphosphoric monoester hydrolase activity; GO:0003723 RNA binding; GO:1901265 nucleoside phosphate binding; GO:0032554 purine deoxyribonucleotide binding; GO:0043167 ion binding; GO:0032567 dGTP binding; GO:0008832 dGTPase activity; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0000166 nucleotide binding; GO:0008270 zinc ion binding; GO:0032552 deoxyribonucleotide binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0097367 carbohydrate derivative binding; GO:0046914 transition metal ion binding; GO:0003824 catalytic activity; GO:0042578 phosphoric ester hydrolase activity; GO:0005488 binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0003676 nucleic acid binding; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0032560 guanyl deoxyribonucleotide binding; GO:0043168 anion binding; GO:0019001 guanyl nucleotide binding; GO:0036094 small molecule binding; GO:0017076 purine nucleotide binding; ",{"$nulls":3},"IPR006674; IPR013761; IPR001660; IPR003607; ","HD domain; Sterile alpha motif/pointed domain; Sterile alpha motif domain; HD/PDEase domain; \r"]
["Q9Y426","C2 domain-containing protein 2 OS=Homo sapiens OX=9606 GN=C2CD2","C2CD2",75.532,5.2258,2.4,1,1,1,1.005,1.248,1.025,0.892,0.835,1.017,0.837,0.122,"extracellular\r",null,"GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0005576 extracellular region; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR000008; ","C2 domain; \r"]
["Q9Y446","Plakophilin-3 OS=Homo sapiens OX=9606 GN=PKP3","PKP3",87.081,78.026,14.4,9,16,9,0.908,0.91,0.919,1.1,1.092,1.068,1.191,5.7e-05,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0034329 cell junction assembly; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0010256 endomembrane system organization; GO:0031424 keratinization; GO:0048869 cellular developmental process; GO:0045216 cell-cell junction organization; GO:0090002 establishment of protein localization to plasma membrane; GO:0044699 single-organism process; GO:0002159 desmosome assembly; GO:1990778 protein localization to cell periphery; GO:0051234 establishment of localization; GO:0022610 biological adhesion; GO:0009913 epidermal cell differentiation; GO:0016337 single organismal cell-cell adhesion; GO:0030154 cell differentiation; GO:1902578 single-organism localization; GO:0022607 cellular component assembly; GO:0007155 cell adhesion; GO:0008544 epidermis development; GO:1902580 single-organism cellular localization; GO:0007275 multicellular organism development; GO:0034613 cellular protein localization; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0090150 establishment of protein localization to membrane; GO:0009987 cellular process; GO:0032502 developmental process; GO:0007043 cell-cell junction assembly; GO:0060429 epithelium development; GO:0043588 skin development; GO:0009888 tissue development; GO:0030216 keratinocyte differentiation; GO:0002934 desmosome organization; GO:0072657 protein localization to membrane; GO:0048731 system development; GO:0070268 cornification; GO:0098609 cell-cell adhesion; GO:0044763 single-organism cellular process; GO:0044802 single-organism membrane organization; GO:0007009 plasma membrane organization; GO:0032501 multicellular organismal process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0072659 protein localization to plasma membrane; GO:0070727 cellular macromolecule localization; GO:0048513 animal organ development; GO:0034330 cell junction organization; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0061024 membrane organization; GO:0098602 single organism cell adhesion; GO:0012501 programmed cell death; GO:0051179 localization; GO:0048856 anatomical structure development; GO:0071840 cellular component organization or biogenesis; GO:0030855 epithelial cell differentiation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005913 cell-cell adherens junction; GO:0005911 cell-cell junction; GO:0005623 cell; GO:0044422 organelle part; GO:0005886 plasma membrane; GO:0030057 desmosome; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0001533 cornified envelope; GO:0044464 cell part; GO:0005622 intracellular; GO:0005912 adherens junction; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0098641 cadherin binding involved in cell-cell adhesion; GO:0050839 cell adhesion molecule binding; GO:0098631 protein binding involved in cell adhesion; GO:0005488 binding; GO:0045296 cadherin binding; GO:0005515 protein binding; GO:0045294 alpha-catenin binding; GO:0098632 protein binding involved in cell-cell adhesion; ",{"$nulls":3},"IPR011989; IPR016024; ","Armadillo-like helical; Armadillo-type fold; \r"]
["Q9Y450","HBS1-like protein OS=Homo sapiens OX=9606 GN=HBS1L","HBS1L",75.472,3.0194,2.2,2,3,2,0.912,0.959,0.84,1.273,1.035,0.988,1.216,0.0934,"cytoplasm\r","GO:0044700 single organism signaling; GO:0006518 peptide metabolic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0007154 cell communication; GO:1901361 organic cyclic compound catabolic process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0006412 translation; GO:0051716 cellular response to stimulus; GO:0010468 regulation of gene expression; GO:0043043 peptide biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic; GO:0043603 cellular amide metabolic process; GO:0023052 signaling; GO:0010605 negative regulation of macromolecule metabolic process; GO:0006401 RNA catabolic process; GO:0016070 RNA metabolic process; GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; GO:0019439 aromatic compound catabolic process; GO:1901575 organic substance catabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0016071 mRNA metabolic process; GO:0050794 regulation of cellular process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0044267 cellular protein metabolic process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:1901566 organonitrogen compound biosynthetic process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0006414 translational elongation; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0043604 amide biosynthetic process; GO:0009056 catabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0003746 translation elongation factor activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0003924 GTPase activity; GO:0043168 anion binding; GO:0019001 guanyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003723 RNA binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0008135 translation factor activity, RNA binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003676 nucleic acid binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0032561 guanyl ribonucleotide binding; GO:0036094 small molecule binding; ","K14416","HBS1; elongation factor 1 alpha-like protein","hsa05134 Legionellosis - Homo sapiens (human); hsa03015 mRNA surveillance pathway - Homo sapiens (human); ","IPR015033; IPR004160; IPR004161; IPR009001; IPR027417; IPR000795; IPR009000; ","\"HBS1-like protein, N-terminal; Translation elongation factor EFTu/EF1A, C-terminal; Translation elongation factor EFTu-like, domain 2; Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal; P-loop containing nucleoside triphosphate hydrolase; Transcription factor, GTP-binding domain; Translation protein, beta-barrel domain; \"\r"]
["Q9Y490","Talin-1 OS=Homo sapiens OX=9606 GN=TLN1","TLN1",269.76,323.31,46.1,101,206,90,1.022,1.041,1.022,0.971,0.976,0.975,0.947,0.00102,"cyto_nucl\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0007596 blood coagulation; GO:0003012 muscle system process; GO:0065008 regulation of biological quality; GO:0045216 cell-cell junction organization; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0030968 endoplasmic reticulum unfolded protein response; GO:0051234 establishment of localization; GO:0009611 response to wounding; GO:0022610 biological adhesion; GO:0016337 single organismal cell-cell adhesion; GO:0030036 actin cytoskeleton organization; GO:0007165 signal transduction; GO:0035966 response to topologically incorrect protein; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0007155 cell adhesion; GO:0044419 interspecies interaction between organisms; GO:0051651 maintenance of location in cell; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0070887 cellular response to chemical stimulus; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0007044 cell-substrate junction assembly; GO:0051716 cellular response to stimulus; GO:0032507 maintenance of protein location in cell; GO:0030866 cortical actin cytoskeleton organization; GO:0030168 platelet activation; GO:0098609 cell-cell adhesion; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0006810 transport; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0032940 secretion by cell; GO:0098602 single organism cell adhesion; GO:0050817 coagulation; GO:0070527 platelet aggregation; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0034329 cell junction assembly; GO:0016043 cellular component organization; GO:0033554 cellular response to stress; GO:0007016 cytoskeletal anchoring at plasma membrane; GO:0035967 cellular response to topologically incorrect protein; GO:0034976 response to endoplasmic reticulum stress; GO:0071310 cellular response to organic substance; GO:0002576 platelet degranulation; GO:0036498 IRE1-mediated unfolded protein response; GO:0030865 cortical cytoskeleton organization; GO:0050896 response to stimulus; GO:0034109 homotypic cell-cell adhesion; GO:0007599 hemostasis; GO:0006936 muscle contraction; GO:1902578 single-organism localization; GO:0016032 viral process; GO:0051235 maintenance of location; GO:0007010 cytoskeleton organization; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0007043 cell-cell junction assembly; GO:0006986 response to unfolded protein; GO:0050878 regulation of body fluid levels; GO:0003008 system process; GO:0045185 maintenance of protein location; GO:0034620 cellular response to unfolded protein; GO:0006950 response to stress; GO:0016192 vesicle-mediated transport; GO:0010033 response to organic substance; GO:0051641 cellular localization; GO:0045055 regulated exocytosis; GO:0070727 cellular macromolecule localization; GO:0042060 wound healing; GO:0034330 cell junction organization; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0001775 cell activation; GO:0006928 movement of cell or subcellular component; GO:0051179 localization; GO:0006887 exocytosis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0032587 ruffle membrane; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005911 cell-cell junction; GO:0005623 cell; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0005925 focal adhesion; GO:0098590 plasma membrane region; GO:0031256 leading edge membrane; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030055 cell-substrate junction; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0031252 cell leading edge; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0070161 anchoring junction; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0001726 ruffle; GO:0031253 cell projection membrane; GO:0009986 cell surface; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0051015 actin filament binding; GO:0005102 receptor binding; GO:0044877 macromolecular complex binding; GO:0030274 LIM domain binding; GO:0005178 integrin binding; GO:0005515 protein binding; GO:0050839 cell adhesion molecule binding; GO:0008092 cytoskeletal protein binding; GO:0005200 structural constituent of cytoskeleton; GO:0017166 vinculin binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0003779 actin binding; GO:0019904 protein domain specific binding; GO:0005198 structural molecule activity; GO:0032403 protein complex binding; ","K06271","TLN; talin","hsa04611 Platelet activation - Homo sapiens (human); hsa04015 Rap1 signaling pathway - Homo sapiens (human); hsa05166 HTLV-I infection - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); ","IPR019748; IPR002558; IPR015224; IPR032425; IPR019749; IPR018979; IPR015009; IPR029071; IPR011993; IPR014352; IPR000299; ","\"FERM central domain; I/LWEQ domain; Talin, central; Talin, N-terminal F0 domain; Band 4.1 domain; FERM, N-terminal; Vinculin-binding site-containing domain; Ubiquitin-related domain; PH domain-like; FERM/acyl-CoA-binding protein, 3-helical bundle; FERM domain; \"\r"]
["Q9Y4D1","Disheveled-associated activator of morphogenesis 1 OS=Homo sapiens OX=9606 GN=DAAM1","DAAM1",123.47,8.5973,3.3,4,5,4,0.959,0.963,1.123,0.944,0.976,1.038,0.971,0.67,"plasma membrane\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0090175 regulation of establishment of planar polarity; GO:0016043 cellular component organization; GO:0007166 cell surface receptor signaling pathway; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0051239 regulation of multicellular organismal process; GO:0035567 non-canonical Wnt signaling pathway; GO:1905330 regulation of morphogenesis of an epithelium; GO:0007165 signal transduction; GO:0030036 actin cytoskeleton organization; GO:0007154 cell communication; GO:2000027 regulation of organ morphogenesis; GO:0016055 Wnt signaling pathway; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0051716 cellular response to stimulus; GO:0044763 single-organism cellular process; GO:0023052 signaling; GO:0198738 cell-cell signaling by wnt; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0007267 cell-cell signaling; GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0060071 Wnt signaling pathway, planar cell polarity pathway; GO:0050793 regulation of developmental process; GO:0065007 biological regulation; GO:2000026 regulation of multicellular organismal development; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0005929 cilium; GO:0016020 membrane; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0071944 cell periphery; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0036064 ciliary basal body; GO:0097517 contractile actin filament bundle; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0031514 motile cilium; GO:0044463 cell projection part; GO:0005623 cell; GO:0015629 actin cytoskeleton; GO:0032432 actin filament bundle; GO:0044422 organelle part; GO:0005886 plasma membrane; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0043226 organelle; GO:0005815 microtubule organizing center; GO:0015630 microtubule cytoskeleton; GO:0044441 ciliary part; GO:0044464 cell part; GO:0005622 intracellular; GO:0001725 stress fiber; GO:0042641 actomyosin; GO:0044444 cytoplasmic part; ","GO:0031267 small GTPase binding; GO:0017048 Rho GTPase binding; GO:0008092 cytoskeletal protein binding; GO:0042802 identical protein binding; GO:0017016 Ras GTPase binding; GO:0005488 binding; GO:0003779 actin binding; GO:0005515 protein binding; GO:0051020 GTPase binding; GO:0019899 enzyme binding; ","K04512","DAAM; dishevelled associated activator of morphogenesis","hsa04310 Wnt signaling pathway - Homo sapiens (human); ","IPR014767; IPR010473; IPR010472; IPR014768; IPR011989; IPR015425; IPR016024; ","\"Diaphanous autoregulatory (DAD) domain; Formin, GTPase-binding domain; Formin, FH3 domain; Rho GTPase-binding/formin homology 3 (GBD/FH3) domain; Armadillo-like helical; Formin, FH2 domain; Armadillo-type fold; \"\r"]
["Q9Y4D7","Plexin-D1 OS=Homo sapiens OX=9606 GN=PLXND1","PLXND1",212,14.011,1.1,2,3,2,0.979,1.005,1.081,0.948,1.076,0.919,0.96,0.499,"plasma membrane\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0065008 regulation of biological quality; GO:0090130 tissue migration; GO:0048732 gland development; GO:0007166 cell surface receptor signaling pathway; GO:0048754 branching morphogenesis of an epithelial tube; GO:0001525 angiogenesis; GO:0043542 endothelial cell migration; GO:0007507 heart development; GO:0051240 positive regulation of multicellular organismal process; GO:0008360 regulation of cell shape; GO:0003151 outflow tract morphogenesis; GO:0032879 regulation of localization; GO:0044093 positive regulation of molecular function; GO:0001569 branching involved in blood vessel morphogenesis; GO:0051099 positive regulation of binding; GO:0060445 branching involved in salivary gland morphogenesis; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0048699 generation of neurons; GO:0031346 positive regulation of cell projection organization; GO:0035239 tube morphogenesis; GO:0001763 morphogenesis of a branching structure; GO:0044763 single-organism cellular process; GO:0048870 cell motility; GO:0032501 multicellular organismal process; GO:0060976 coronary vasculature development; GO:0048513 animal organ development; GO:0051336 regulation of hydrolase activity; GO:0010631 epithelial cell migration; GO:0050790 regulation of catalytic activity; GO:0009887 animal organ morphogenesis; GO:0045765 regulation of angiogenesis; GO:0051094 positive regulation of developmental process; GO:0010975 regulation of neuron projection development; GO:0050794 regulation of cellular process; GO:0072359 circulatory system development; GO:0044707 single-multicellular organism process; GO:0002009 morphogenesis of an epithelium; GO:0007162 negative regulation of cell adhesion; GO:0090132 epithelium migration; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0045597 positive regulation of cell differentiation; GO:0051239 regulation of multicellular organismal process; GO:0009653 anatomical structure morphogenesis; GO:0050772 positive regulation of axonogenesis; GO:2000145 regulation of cell motility; GO:0007275 multicellular organism development; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0060562 epithelial tube morphogenesis; GO:0051270 regulation of cellular component movement; GO:0003279 cardiac septum development; GO:0048731 system development; GO:0051960 regulation of nervous system development; GO:0060284 regulation of cell development; GO:0007416 synapse assembly; GO:0030334 regulation of cell migration; GO:0072358 cardiovascular system development; GO:0060600 dichotomous subdivision of an epithelial terminal unit; GO:0050808 synapse organization; GO:0050770 regulation of axonogenesis; GO:0030155 regulation of cell adhesion; GO:0061138 morphogenesis of a branching epithelium; GO:0010976 positive regulation of neuron projection development; GO:0006928 movement of cell or subcellular component; GO:0050769 positive regulation of neurogenesis; GO:0010769 regulation of cell morphogenesis involved in differentiation; GO:0007435 salivary gland morphogenesis; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0045666 positive regulation of neuron differentiation; GO:0051674 localization of cell; GO:0001568 blood vessel development; GO:0032092 positive regulation of protein binding; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0051130 positive regulation of cellular component organization; GO:0048729 tissue morphogenesis; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0048514 blood vessel morphogenesis; GO:0010720 positive regulation of cell development; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0035295 tube development; GO:0009888 tissue development; GO:0003007 heart morphogenesis; GO:0051098 regulation of binding; GO:0051962 positive regulation of nervous system development; GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching; GO:0001944 vasculature development; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0035904 aorta development; GO:0050789 regulation of biological process; GO:0045664 regulation of neuron differentiation; GO:0060840 artery development; GO:0001667 ameboidal-type cell migration; GO:0065009 regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0040011 locomotion; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0016477 cell migration; GO:0016043 cellular component organization; GO:0007431 salivary gland development; GO:0010770 positive regulation of cell morphogenesis involved in differentiation; GO:0031344 regulation of cell projection organization; GO:0050896 response to stimulus; GO:0043393 regulation of protein binding; GO:0030154 cell differentiation; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0035272 exocrine system development; GO:1901342 regulation of vasculature development; GO:0048518 positive regulation of biological process; GO:0003205 cardiac chamber development; GO:0044767 single-organism developmental process; GO:0022603 regulation of anatomical structure morphogenesis; GO:0051128 regulation of cellular component organization; GO:0040012 regulation of locomotion; GO:0022604 regulation of cell morphogenesis; GO:0071526 semaphorin-plexin signaling pathway; GO:0022612 gland morphogenesis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:0050767 regulation of neurogenesis; ","GO:0031252 cell leading edge; GO:0016020 membrane; GO:0042995 cell projection; GO:0031226 intrinsic component of plasma membrane; GO:0044459 plasma membrane part; GO:0044425 membrane part; GO:0044464 cell part; GO:0071944 cell periphery; GO:0030027 lamellipodium; GO:0031224 intrinsic component of membrane; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005886 plasma membrane; ","GO:0038023 signaling receptor activity; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0005488 binding; GO:0017154 semaphorin receptor activity; GO:0019904 protein domain specific binding; GO:0005515 protein binding; GO:0004888 transmembrane signaling receptor activity; GO:0004871 signal transducer activity; GO:0099600 transmembrane receptor activity; ","K06822",null,null,"IPR013548; IPR013783; IPR014756; IPR015943; IPR016201; IPR008936; IPR002909; IPR001627; ","\"Plexin, cytoplasmic RasGAP domain; Immunoglobulin-like fold; Immunoglobulin E-set; WD40/YVTN repeat-like-containing domain; PSI domain; Rho GTPase activation protein; IPT domain; Sema domain; \"\r"]
["Q9Y4E8","Ubiquitin carboxyl-terminal hydrolase 15 OS=Homo sapiens OX=9606 GN=USP15","USP15",112.42,43.944,10.1,9,11,8,0.847,0.993,0.937,1.068,1.111,1.098,1.18,0.025,"cytoplasm\r","GO:0044700 single organism signaling; GO:0070646 protein modification by small protein removal; GO:0007166 cell surface receptor signaling pathway; GO:0071560 cellular response to transforming growth factor beta stimulus; GO:0044699 single-organism process; GO:0071363 cellular response to growth factor stimulus; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0030509 BMP signaling pathway; GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0009719 response to endogenous stimulus; GO:0070848 response to growth factor; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0070887 cellular response to chemical stimulus; GO:0010468 regulation of gene expression; GO:0051716 cellular response to stimulus; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0031323 regulation of cellular metabolic process; GO:0071559 response to transforming growth factor beta; GO:0023052 signaling; GO:1903506 regulation of nucleic acid-templated transcription; GO:1901575 organic substance catabolic process; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0035616 histone H2B conserved C-terminal lysine deubiquitination; GO:0030163 protein catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006464 cellular protein modification process; GO:0060389 pathway-restricted SMAD protein phosphorylation; GO:0006325 chromatin organization; GO:0071772 response to BMP; GO:0036211 protein modification process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016310 phosphorylation; GO:0016043 cellular component organization; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0016570 histone modification; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0050896 response to stimulus; GO:0016579 protein deubiquitination; GO:0071704 organic substance metabolic process; GO:0006468 protein phosphorylation; GO:0009889 regulation of biosynthetic process; GO:0044248 cellular catabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0006508 proteolysis; GO:0016569 covalent chromatin modification; GO:0009987 cellular process; GO:0071773 cellular response to BMP stimulus; GO:0043632 modification-dependent macromolecule catabolic process; GO:0016578 histone deubiquitination; GO:0044265 cellular macromolecule catabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0019941 modification-dependent protein catabolic process; GO:0007179 transforming growth factor beta receptor signaling pathway; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0010033 response to organic substance; GO:0044238 primary metabolic process; GO:0035520 monoubiquitinated protein deubiquitination; GO:0051252 regulation of RNA metabolic process; GO:0051276 chromosome organization; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0071495 cellular response to endogenous stimulus; GO:0009057 macromolecule catabolic process; GO:0043412 macromolecule modification; GO:0009056 catabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; GO:0005829 cytosol; GO:0044444 cytoplasmic part; ","GO:0042393 histone binding; GO:0004843 thiol-dependent ubiquitin-specific protease activity; GO:0008233 peptidase activity; GO:0005102 receptor binding; GO:0005160 transforming growth factor beta receptor binding; GO:0005126 cytokine receptor binding; GO:0019783 ubiquitin-like protein-specific protease activity; GO:0005515 protein binding; GO:0008234 cysteine-type peptidase activity; GO:0016787 hydrolase activity; GO:0004175 endopeptidase activity; GO:0061649 ubiquitinated histone binding; GO:0042802 identical protein binding; GO:0036459 thiol-dependent ubiquitinyl hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0101005 ubiquitinyl hydrolase activity; GO:0004197 cysteine-type endopeptidase activity; GO:0046332 SMAD binding; ","K11835",null,null,"IPR028135; IPR029071; IPR006615; IPR028889; IPR001394; IPR029346; IPR013792; ","\"Ubiquitin-like domain, USP-type; Ubiquitin-related domain; Peptidase C19, ubiquitin-specific peptidase, DUSP domain; Ubiquitin specific protease domain; Peptidase C19, ubiquitin carboxyl-terminal hydrolase; Ubiquitin carboxyl-terminal hydrolase, C-terminal; RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta; \"\r"]
["Q9Y4F1","FERM, ARHGEF and pleckstrin domain-containing protein 1 OS=Homo sapiens OX=9606 GN=FARP1","FARP1",118.63,11.889,4,4,4,4,1.17,1.403,1.074,0.605,0.86,0.921,0.654,0.0462,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0023051 regulation of signaling; GO:0048869 cellular developmental process; GO:0048666 neuron development; GO:0032989 cellular component morphogenesis; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0010923 negative regulation of phosphatase activity; GO:0010646 regulation of cell communication; GO:0032990 cell part morphogenesis; GO:0022607 cellular component assembly; GO:0044093 positive regulation of molecular function; GO:0048858 cell projection morphogenesis; GO:0035303 regulation of dephosphorylation; GO:0051056 regulation of small GTPase mediated signal transduction; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0035305 negative regulation of dephosphorylation; GO:0051174 regulation of phosphorus metabolic process; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0048812 neuron projection morphogenesis; GO:0031323 regulation of cellular metabolic process; GO:0043086 negative regulation of catalytic activity; GO:0032501 multicellular organismal process; GO:0000902 cell morphogenesis; GO:0050789 regulation of biological process; GO:0051336 regulation of hydrolase activity; GO:0030030 cell projection organization; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0048813 dendrite morphogenesis; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0044092 negative regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:0048856 anatomical structure development; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0016043 cellular component organization; GO:0016358 dendrite development; GO:0046578 regulation of Ras protein signal transduction; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0031324 negative regulation of cellular metabolic process; GO:0051346 negative regulation of hydrolase activity; GO:0048468 cell development; GO:0000904 cell morphogenesis involved in differentiation; GO:0009653 anatomical structure morphogenesis; GO:0030154 cell differentiation; GO:0051345 positive regulation of hydrolase activity; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:1902531 regulation of intracellular signal transduction; GO:0010921 regulation of phosphatase activity; GO:0043547 positive regulation of GTPase activity; GO:0048731 system development; GO:0007416 synapse assembly; GO:0031175 neuron projection development; GO:0050808 synapse organization; GO:0009892 negative regulation of metabolic process; GO:0043085 positive regulation of catalytic activity; GO:0030182 neuron differentiation; GO:0044767 single-organism developmental process; GO:0010563 negative regulation of phosphorus metabolic process; GO:0035023 regulation of Rho protein signal transduction; GO:0045936 negative regulation of phosphate metabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0030425 dendrite; GO:0019898 extrinsic component of membrane; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0098858 actin-based cell projection; GO:0031234 extrinsic component of cytoplasmic side of plasma membrane; GO:0005623 cell; GO:0009898 cytoplasmic side of plasma membrane; GO:0098562 cytoplasmic side of membrane; GO:0043197 dendritic spine; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0044309 neuron spine; GO:0044464 cell part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0030175 filopodium; GO:0043005 neuron projection; GO:0097458 neuron part; GO:0044456 synapse part; GO:0098552 side of membrane; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0019897 extrinsic component of plasma membrane; GO:0005829 cytosol; GO:0044463 cell projection part; GO:0005886 plasma membrane; GO:0045202 synapse; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0044459 plasma membrane part; GO:0098794 postsynapse; GO:0044444 cytoplasmic part; ","GO:0008092 cytoskeletal protein binding; GO:0030676 Rac guanyl-nucleotide exchange factor activity; GO:0005085 guanyl-nucleotide exchange factor activity; GO:0005488 binding; GO:0005515 protein binding; GO:0005088 Ras guanyl-nucleotide exchange factor activity; GO:0098772 molecular function regulator; GO:0005089 Rho guanyl-nucleotide exchange factor activity; ","K17477",null,null,"IPR019748; IPR018980; IPR000219; IPR001849; IPR019749; IPR018979; IPR011993; IPR029071; IPR014847; IPR014352; IPR000299; ","\"FERM central domain; FERM, C-terminal PH-like domain; Dbl homology (DH) domain; Pleckstrin homology domain; Band 4.1 domain; FERM, N-terminal; PH domain-like; Ubiquitin-related domain; FERM adjacent (FA); FERM/acyl-CoA-binding protein, 3-helical bundle; FERM domain; \"\r"]
["Q9Y4G6","Talin-2 OS=Homo sapiens OX=9606 GN=TLN2","TLN2",271.61,242.52,21.2,46,61,35,1.13,1.117,1.112,0.868,0.882,0.907,0.791,6.42e-05,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0007043 cell-cell junction assembly; GO:0016043 cellular component organization; GO:0034329 cell junction assembly; GO:0065008 regulation of biological quality; GO:0032507 maintenance of protein location in cell; GO:0007016 cytoskeletal anchoring at plasma membrane; GO:0045185 maintenance of protein location; GO:0045216 cell-cell junction organization; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0051641 cellular localization; GO:0022610 biological adhesion; GO:1902589 single-organism organelle organization; GO:0070727 cellular macromolecule localization; GO:1902578 single-organism localization; GO:0034330 cell junction organization; GO:0022607 cellular component assembly; GO:0006996 organelle organization; GO:0007155 cell adhesion; GO:0051235 maintenance of location; GO:0051651 maintenance of location in cell; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0007010 cytoskeleton organization; GO:0051179 localization; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0031252 cell leading edge; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0070161 anchoring junction; GO:0044424 intracellular part; GO:0005623 cell; GO:0005911 cell-cell junction; GO:0015629 actin cytoskeleton; GO:0005886 plasma membrane; GO:0045202 synapse; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0043226 organelle; GO:0005925 focal adhesion; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:0001726 ruffle; GO:0030055 cell-substrate junction; GO:0005924 cell-substrate adherens junction; ","GO:0051015 actin filament binding; GO:0008092 cytoskeletal protein binding; GO:0005200 structural constituent of cytoskeleton; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0003779 actin binding; GO:0005515 protein binding; GO:0005198 structural molecule activity; GO:0032403 protein complex binding; ","K06271","TLN; talin","hsa04611 Platelet activation - Homo sapiens (human); hsa04015 Rap1 signaling pathway - Homo sapiens (human); hsa05166 HTLV-I infection - Homo sapiens (human); hsa04510 Focal adhesion - Homo sapiens (human); ","IPR019748; IPR002558; IPR015224; IPR032425; IPR018979; IPR019749; IPR015009; IPR029071; IPR011993; IPR000299; IPR014352; ","\"FERM central domain; I/LWEQ domain; Talin, central; Talin, N-terminal F0 domain; FERM, N-terminal; Band 4.1 domain; Vinculin-binding site-containing domain; Ubiquitin-related domain; PH domain-like; FERM domain; FERM/acyl-CoA-binding protein, 3-helical bundle; \"\r"]
["Q9Y4I1","Unconventional myosin-Va OS=Homo sapiens OX=9606 GN=MYO5A","MYO5A",215.4,3.7108,1,2,2,2,0.986,0.927,0.953,1.029,0.989,1.117,1.094,0.091,"cytoplasm\r","GO:0044700 single organism signaling; GO:0021700 developmental maturation; GO:0009914 hormone transport; GO:0065008 regulation of biological quality; GO:0051643 endoplasmic reticulum localization; GO:0007272 ensheathment of neurons; GO:0007601 visual perception; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0050877 neurological system process; GO:0010469 regulation of receptor activity; GO:0008610 lipid biosynthetic process; GO:0007610 behavior; GO:0051875 pigment granule localization; GO:0008152 metabolic process; GO:0032879 regulation of localization; GO:1901019 regulation of calcium ion transmembrane transporter activity; GO:0032400 melanosome localization; GO:0009719 response to endogenous stimulus; GO:0008544 epidermis development; GO:0009306 protein secretion; GO:0032787 monocarboxylic acid metabolic process; GO:0008104 protein localization; GO:0042886 amide transport; GO:1901652 response to peptide; GO:0030050 vesicle transport along actin filament; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0043588 skin development; GO:0072657 protein localization to membrane; GO:0002790 peptide secretion; GO:0044281 small molecule metabolic process; GO:0043269 regulation of ion transport; GO:0044763 single-organism cellular process; GO:1901617 organic hydroxy compound biosynthetic process; GO:0007009 plasma membrane organization; GO:0032501 multicellular organismal process; GO:0042552 myelination; GO:0006810 transport; GO:0034762 regulation of transmembrane transport; GO:0098773 skin epidermis development; GO:0030072 peptide hormone secretion; GO:0010243 response to organonitrogen compound; GO:0048513 animal organ development; GO:0007267 cell-cell signaling; GO:0018958 phenol-containing compound metabolic process; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:1901698 response to nitrogen compound; GO:0032869 cellular response to insulin stimulus; GO:2001257 regulation of cation channel activity; GO:0009887 animal organ morphogenesis; GO:0010817 regulation of hormone levels; GO:0032412 regulation of ion transmembrane transporter activity; GO:1901362 organic cyclic compound biosynthetic process; GO:0001942 hair follicle development; GO:0043436 oxoacid metabolic process; GO:0051640 organelle localization; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0044707 single-multicellular organism process; GO:0042759 long-chain fatty acid biosynthetic process; GO:1901615 organic hydroxy compound metabolic process; GO:0042303 molting cycle; GO:0030073 insulin secretion; GO:1901700 response to oxygen-containing compound; GO:0032844 regulation of homeostatic process; GO:1990778 protein localization to cell periphery; GO:0030705 cytoskeleton-dependent intracellular transport; GO:0060341 regulation of cellular localization; GO:0009653 anatomical structure morphogenesis; GO:1902578 single-organism localization; GO:0019438 aromatic compound biosynthetic process; GO:0010959 regulation of metal ion transport; GO:1902580 single-organism cellular localization; GO:0048820 hair follicle maturation; GO:0007275 multicellular organism development; GO:0050848 regulation of calcium-mediated signaling; GO:0034613 cellular protein localization; GO:0009966 regulation of signal transduction; GO:0032409 regulation of transporter activity; GO:1904062 regulation of cation transmembrane transport; GO:1902531 regulation of intracellular signal transduction; GO:0051282 regulation of sequestering of calcium ion; GO:0044711 single-organism biosynthetic process; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0042438 melanin biosynthetic process; GO:0051924 regulation of calcium ion transport; GO:0071702 organic substance transport; GO:0023061 signal release; GO:0010033 response to organic substance; GO:0022405 hair cycle process; GO:0044550 secondary metabolite biosynthetic process; GO:0051656 establishment of organelle localization; GO:0044238 primary metabolic process; GO:0050808 synapse organization; GO:0042633 hair cycle; GO:1901576 organic substance biosynthetic process; GO:0045184 establishment of protein localization; GO:0072659 protein localization to plasma membrane; GO:0099536 synaptic signaling; GO:0001676 long-chain fatty acid metabolic process; GO:0061024 membrane organization; GO:0030029 actin filament-based process; GO:0044283 small molecule biosynthetic process; GO:0043473 pigmentation; GO:0006928 movement of cell or subcellular component; GO:0007268 chemical synaptic transmission; GO:0006892 post-Golgi vesicle-mediated transport; GO:0051179 localization; GO:0033059 cellular pigmentation; GO:0072330 monocarboxylic acid biosynthetic process; GO:0006887 exocytosis; GO:0030048 actin filament-based movement; GO:0046148 pigment biosynthetic process; GO:0010256 endomembrane system organization; GO:0031585 regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; GO:0006582 melanin metabolic process; GO:0016053 organic acid biosynthetic process; GO:0048869 cellular developmental process; GO:0046189 phenol-containing compound biosynthetic process; GO:0023051 regulation of signaling; GO:0031987 locomotion involved in locomotory behavior; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0051234 establishment of localization; GO:0046879 hormone secretion; GO:0051649 establishment of localization in cell; GO:0010646 regulation of cell communication; GO:1901653 cellular response to peptide; GO:0022404 molting cycle process; GO:0007154 cell communication; GO:0099515 actin filament-based transport; GO:0098916 anterograde trans-synaptic signaling; GO:0051904 pigment granule transport; GO:0033036 macromolecule localization; GO:0070887 cellular response to chemical stimulus; GO:0006629 lipid metabolic process; GO:0019748 secondary metabolic process; GO:0032502 developmental process; GO:0051650 establishment of vesicle localization; GO:0060429 epithelium development; GO:0007600 sensory perception; GO:0009888 tissue development; GO:0051279 regulation of release of sequestered calcium ion into cytosol; GO:1901360 organic cyclic compound metabolic process; GO:0022898 regulation of transmembrane transporter activity; GO:0023052 signaling; GO:0006633 fatty acid biosynthetic process; GO:0030318 melanocyte differentiation; GO:1902582 single-organism intracellular transport; GO:0042476 odontogenesis; GO:0071417 cellular response to organonitrogen compound; GO:0099518 vesicle cytoskeletal trafficking; GO:0046394 carboxylic acid biosynthetic process; GO:0042221 response to chemical; GO:0032868 response to insulin; GO:0050789 regulation of biological process; GO:0043434 response to peptide hormone; GO:1901699 cellular response to nitrogen compound; GO:0032870 cellular response to hormone stimulus; GO:0032940 secretion by cell; GO:0065009 regulation of molecular function; GO:0040011 locomotion; GO:0006082 organic acid metabolic process; GO:0048856 anatomical structure development; GO:0015833 peptide transport; GO:0071695 anatomical structure maturation; GO:0016043 cellular component organization; GO:2000021 regulation of ion homeostasis; GO:0006725 cellular aromatic compound metabolic process; GO:0071310 cellular response to organic substance; GO:0008366 axon ensheathment; GO:0048193 Golgi vesicle transport; GO:0048066 developmental pigmentation; GO:0050896 response to stimulus; GO:0050931 pigment cell differentiation; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0051905 establishment of pigment granule localization; GO:0071375 cellular response to peptide hormone stimulus; GO:1903169 regulation of calcium ion transmembrane transport; GO:0051648 vesicle localization; GO:0099537 trans-synaptic signaling; GO:0032402 melanosome transport; GO:0009987 cellular process; GO:0003008 system process; GO:0042440 pigment metabolic process; GO:0051049 regulation of transport; GO:0090279 regulation of calcium ion import; GO:0044802 single-organism membrane organization; GO:0006631 fatty acid metabolic process; GO:0050953 sensory perception of light stimulus; GO:0032252 secretory granule localization; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0070727 cellular macromolecule localization; GO:1901701 cellular response to oxygen-containing compound; GO:0034765 regulation of ion transmembrane transport; GO:0071495 cellular response to endogenous stimulus; GO:0044767 single-organism developmental process; GO:0019752 carboxylic acid metabolic process; GO:0010522 regulation of calcium ion transport into cytosol; GO:0032401 establishment of melanosome localization; GO:0007626 locomotory behavior; GO:0009725 response to hormone; GO:0071705 nitrogen compound transport; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0035371 microtubule plus-end; GO:0005737 cytoplasm; GO:0043025 neuronal cell body; GO:0032991 macromolecular complex; GO:0098858 actin-based cell projection; GO:0005623 cell; GO:0099080 supramolecular complex; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0099503 secretory vesicle; GO:0030175 filopodium; GO:0043005 neuron projection; GO:0016459 myosin complex; GO:0043227 membrane-bounded organelle; GO:0042641 actomyosin; GO:0097458 neuron part; GO:0031252 cell leading edge; GO:0005929 cilium; GO:0099513 polymeric cytoskeletal fiber; GO:0042995 cell projection; GO:0044430 cytoskeletal part; GO:0032433 filopodium tip; GO:0030427 site of polarized growth; GO:0005576 extracellular region; GO:0099081 supramolecular polymer; GO:0043231 intracellular membrane-bounded organelle; GO:0045111 intermediate filament cytoskeleton; GO:0005882 intermediate filament; GO:0097733 photoreceptor cell cilium; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0005874 microtubule; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0097730 non-motile cilium; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:1990752 microtubule end; GO:0030426 growth cone; GO:0097731 9+0 non-motile cilium; GO:0048770 pigment granule; GO:0005856 cytoskeleton; GO:0015630 microtubule cytoskeleton; GO:0044441 ciliary part; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0001750 photoreceptor outer segment; GO:0030141 secretory granule; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0042470 melanosome; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044463 cell projection part; GO:0005829 cytosol; GO:0015629 actin cytoskeleton; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0001726 ruffle; GO:0032593 insulin-responsive compartment; GO:0044297 cell body; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0003774 motor activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0017137 Rab GTPase binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0008092 cytoskeletal protein binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0017016 Ras GTPase binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0051020 GTPase binding; GO:0000146 microfilament motor activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0031267 small GTPase binding; GO:0003723 RNA binding; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0005516 calmodulin binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003676 nucleic acid binding; GO:0003779 actin binding; GO:0046872 metal ion binding; GO:0032555 purine ribonucleotide binding; GO:0005509 calcium ion binding; GO:0001883 purine nucleoside binding; GO:0019899 enzyme binding; GO:0036094 small molecule binding; ","K10357",null,null,"IPR002710; IPR027417; IPR001609; ","\"Dilute domain; P-loop containing nucleoside triphosphate hydrolase; Myosin head, motor domain; \"\r"]
["Q9Y4K1","Beta/gamma crystallin domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CRYBG1","CRYBG1",188.67,70.217,10,12,14,12,0.934,0.942,0.965,1.073,0.994,1.093,1.112,0.0261,"nucleus\r",null,null,"GO:0030246 carbohydrate binding; GO:0005488 binding; ",{"$nulls":3},"IPR011024; IPR001064; IPR000772; ","\"Gamma-crystallin-related; Beta/gamma crystallin; Ricin B, lectin domain; \"\r"]
["Q9Y4L1","Hypoxia up-regulated protein 1 OS=Homo sapiens OX=9606 GN=HYOU1","HYOU1",111.33,98.46,20,16,19,16,0.92,0.956,0.948,1.07,1.074,1.035,1.126,0.00202,"endoplasmic reticulum\r","GO:0044700 single organism signaling; GO:0010941 regulation of cell death; GO:0009968 negative regulation of signal transduction; GO:0023051 regulation of signaling; GO:0043523 regulation of neuron apoptotic process; GO:0044699 single-organism process; GO:1905897 regulation of response to endoplasmic reticulum stress; GO:0030968 endoplasmic reticulum unfolded protein response; GO:0051234 establishment of localization; GO:0002931 response to ischemia; GO:2001233 regulation of apoptotic signaling pathway; GO:0007165 signal transduction; GO:0051649 establishment of localization in cell; GO:0010646 regulation of cell communication; GO:0035966 response to topologically incorrect protein; GO:2001243 negative regulation of intrinsic apoptotic signaling pathway; GO:0007154 cell communication; GO:0070887 cellular response to chemical stimulus; GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway; GO:0051716 cellular response to stimulus; GO:0023052 signaling; GO:2001234 negative regulation of apoptotic signaling pathway; GO:1900038 negative regulation of cellular response to hypoxia; GO:0006810 transport; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:1902532 negative regulation of intracellular signal transduction; GO:0080135 regulation of cellular response to stress; GO:0048583 regulation of response to stimulus; GO:0060548 negative regulation of cell death; GO:1903297 regulation of hypoxia-induced intrinsic apoptotic signaling pathway; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0033554 cellular response to stress; GO:0043069 negative regulation of programmed cell death; GO:0034976 response to endoplasmic reticulum stress; GO:0035967 cellular response to topologically incorrect protein; GO:0009628 response to abiotic stimulus; GO:0071310 cellular response to organic substance; GO:0043067 regulation of programmed cell death; GO:0048193 Golgi vesicle transport; GO:0036498 IRE1-mediated unfolded protein response; GO:0080134 regulation of response to stress; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0050896 response to stimulus; GO:1903298 negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway; GO:1900037 regulation of cellular response to hypoxia; GO:1903382 negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway; GO:0023057 negative regulation of signaling; GO:0043524 negative regulation of neuron apoptotic process; GO:0010648 negative regulation of cell communication; GO:0043066 negative regulation of apoptotic process; GO:0001666 response to hypoxia; GO:0070482 response to oxygen levels; GO:1902235 regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway; GO:0006898 receptor-mediated endocytosis; GO:0071453 cellular response to oxygen levels; GO:0009987 cellular process; GO:0009966 regulation of signal transduction; GO:1901214 regulation of neuron death; GO:1901215 negative regulation of neuron death; GO:0071456 cellular response to hypoxia; GO:0006986 response to unfolded protein; GO:1903381 regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway; GO:1902531 regulation of intracellular signal transduction; GO:0034620 cellular response to unfolded protein; GO:0006950 response to stress; GO:0016192 vesicle-mediated transport; GO:0010033 response to organic substance; GO:0048585 negative regulation of response to stimulus; GO:0006897 endocytosis; GO:1903573 negative regulation of response to endoplasmic reticulum stress; GO:0051641 cellular localization; GO:2001242 regulation of intrinsic apoptotic signaling pathway; GO:0036293 response to decreased oxygen levels; GO:0051179 localization; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0036294 cellular response to decreased oxygen levels; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0005790 smooth endoplasmic reticulum; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0031983 vesicle lumen; GO:0005925 focal adhesion; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0005912 adherens junction; GO:1903561 extracellular vesicle; GO:0030055 cell-substrate junction; GO:0030139 endocytic vesicle; GO:0043227 membrane-bounded organelle; GO:0005924 cell-substrate adherens junction; GO:0043233 organelle lumen; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0005788 endoplasmic reticulum lumen; GO:0044446 intracellular organelle part; GO:0070161 anchoring junction; GO:0012505 endomembrane system; GO:0034663 endoplasmic reticulum chaperone complex; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0044432 endoplasmic reticulum part; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0071682 endocytic vesicle lumen; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0051087 chaperone binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ","K09486","HYOU1; hypoxia up-regulated 1","hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); ","IPR029048; IPR029047; ","\"Heat shock protein 70kD, C-terminal domain; Heat shock protein 70kD, peptide-binding domain; \"\r"]
["Q9Y4P3","Transducin beta-like protein 2 OS=Homo sapiens OX=9606 GN=TBL2","TBL2",49.797,15.393,11.9,5,5,5,1.183,1.043,1.015,0.936,0.878,0.966,0.858,0.0505,"extracellular\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0033554 cellular response to stress; GO:0009267 cellular response to starvation; GO:0034976 response to endoplasmic reticulum stress; GO:0035967 cellular response to topologically incorrect protein; GO:0009628 response to abiotic stimulus; GO:0071310 cellular response to organic substance; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0030968 endoplasmic reticulum unfolded protein response; GO:0031669 cellular response to nutrient levels; GO:0009991 response to extracellular stimulus; GO:0009605 response to external stimulus; GO:0007165 signal transduction; GO:0035966 response to topologically incorrect protein; GO:0007154 cell communication; GO:0001666 response to hypoxia; GO:0070482 response to oxygen levels; GO:0071453 cellular response to oxygen levels; GO:0009987 cellular process; GO:0070887 cellular response to chemical stimulus; GO:0071456 cellular response to hypoxia; GO:0051716 cellular response to stimulus; GO:0006986 response to unfolded protein; GO:0006950 response to stress; GO:0034620 cellular response to unfolded protein; GO:0042149 cellular response to glucose starvation; GO:0071496 cellular response to external stimulus; GO:0010033 response to organic substance; GO:0023052 signaling; GO:0031668 cellular response to extracellular stimulus; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0042594 response to starvation; GO:0036293 response to decreased oxygen levels; GO:0031667 response to nutrient levels; GO:0036294 cellular response to decreased oxygen levels; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0043229 intracellular organelle; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044432 endoplasmic reticulum part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0031227 intrinsic component of endoplasmic reticulum membrane; GO:0030176 integral component of endoplasmic reticulum membrane; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0031369 translation initiation factor binding; GO:0005488 binding; GO:0019901 protein kinase binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0019900 kinase binding; GO:0019899 enzyme binding; GO:0051219 phosphoprotein binding; ",{"$nulls":3},"IPR017986; IPR015943; ","WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain; \r"]
["Q9Y4P8","WD repeat domain phosphoinositide-interacting protein 2 OS=Homo sapiens OX=9606 GN=WIPI2","WIPI2",49.408,11.046,5.7,2,2,2,0.905,0.994,0.978,0.916,1.038,1.165,1.084,0.365,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0016043 cellular component organization; GO:1905037 autophagosome organization; GO:0006914 autophagy; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0070925 organelle assembly; GO:0022607 cellular component assembly; GO:0006996 organelle organization; GO:0044248 cellular catabolic process; GO:0007033 vacuole organization; GO:0009056 catabolic process; GO:0009987 cellular process; GO:0000045 autophagosome assembly; GO:0071840 cellular component organization or biogenesis; GO:0016236 macroautophagy; ","GO:0016020 membrane; GO:0044464 cell part; GO:0005622 intracellular; GO:0098805 whole membrane; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0043234 protein complex; GO:0005829 cytosol; GO:0000407 pre-autophagosomal structure; GO:0034045 pre-autophagosomal structure membrane; GO:0044444 cytoplasmic part; ","GO:1901981 phosphatidylinositol phosphate binding; GO:0032266 phosphatidylinositol-3-phosphate binding; GO:0010314 phosphatidylinositol-5-phosphate binding; GO:0005488 binding; GO:0005543 phospholipid binding; GO:0035091 phosphatidylinositol binding; GO:0043167 ion binding; GO:0008289 lipid binding; GO:0080025 phosphatidylinositol-3,5-bisphosphate binding; GO:0005515 protein binding; GO:0043168 anion binding; GO:1902936 phosphatidylinositol bisphosphate binding; ","K17908","WIPI; autophagy-related protein 18","hsa04136 Autophagy - other - Homo sapiens (human); hsa04140 Autophagy - animal - Homo sapiens (human); ","IPR017986; IPR015943; ","WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain; \r"]
["Q9Y4W6","AFG3-like protein 2 OS=Homo sapiens OX=9606 GN=AFG3L2","AFG3L2",88.583,54.647,18.3,12,15,11,0.873,1.045,1.004,1.035,1.03,0.944,1.03,0.64,"plasma membrane\r","GO:0007528 neuromuscular junction development; GO:0065008 regulation of biological quality; GO:0072503 cellular divalent inorganic cation homeostasis; GO:0048747 muscle fiber development; GO:0007272 ensheathment of neurons; GO:0048666 neuron development; GO:0006839 mitochondrial transport; GO:0048869 cellular developmental process; GO:0060004 reflex; GO:0032989 cellular component morphogenesis; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0016485 protein processing; GO:0044237 cellular metabolic process; GO:0051234 establishment of localization; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0032990 cell part morphogenesis; GO:0007005 mitochondrion organization; GO:0055065 metal ion homeostasis; GO:0048858 cell projection morphogenesis; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0044801 single-organism membrane fusion; GO:0060401 cytosolic calcium ion transport; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0098655 cation transmembrane transport; GO:0040014 regulation of multicellular organism growth; GO:0050801 ion homeostasis; GO:0048699 generation of neurons; GO:0055074 calcium ion homeostasis; GO:0098771 inorganic ion homeostasis; GO:0044763 single-organism cellular process; GO:0061025 membrane fusion; GO:0019725 cellular homeostasis; GO:0048812 neuron projection morphogenesis; GO:0032501 multicellular organismal process; GO:0006874 cellular calcium ion homeostasis; GO:0000902 cell morphogenesis; GO:0006851 mitochondrial calcium ion transport; GO:0006810 transport; GO:0042552 myelination; GO:0007007 inner mitochondrial membrane organization; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0055002 striated muscle cell development; GO:0030030 cell projection organization; GO:0044260 cellular macromolecule metabolic process; GO:0021675 nerve development; GO:0070509 calcium ion import; GO:0060013 righting reflex; GO:0072507 divalent inorganic cation homeostasis; GO:0048856 anatomical structure development; GO:0098662 inorganic cation transmembrane transport; GO:0055001 muscle cell development; GO:0016043 cellular component organization; GO:0042407 cristae formation; GO:0044707 single-multicellular organism process; GO:0040008 regulation of growth; GO:0034220 ion transmembrane transport; GO:0072511 divalent inorganic cation transport; GO:0007006 mitochondrial membrane organization; GO:0030001 metal ion transport; GO:0030003 cellular cation homeostasis; GO:0008366 axon ensheathment; GO:0044267 cellular protein metabolic process; GO:0050896 response to stimulus; GO:0048638 regulation of developmental growth; GO:0051239 regulation of multicellular organismal process; GO:0048468 cell development; GO:0055082 cellular chemical homeostasis; GO:0071704 organic substance metabolic process; GO:0000904 cell morphogenesis involved in differentiation; GO:0009653 anatomical structure morphogenesis; GO:0042592 homeostatic process; GO:0036444 mitochondrial calcium uptake; GO:0030154 cell differentiation; GO:0048667 cell morphogenesis involved in neuron differentiation; GO:0006816 calcium ion transport; GO:0006812 cation transport; GO:0055080 cation homeostasis; GO:0007409 axonogenesis; GO:1990542 mitochondrial transmembrane transport; GO:0008053 mitochondrial fusion; GO:0061061 muscle structure development; GO:0006508 proteolysis; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0034982 mitochondrial protein processing; GO:0048878 chemical homeostasis; GO:0070588 calcium ion transmembrane transport; GO:0051146 striated muscle cell differentiation; GO:0098660 inorganic ion transmembrane transport; GO:0048731 system development; GO:0044802 single-organism membrane organization; GO:0051560 mitochondrial calcium ion homeostasis; GO:0048284 organelle fusion; GO:0044238 primary metabolic process; GO:0031175 neuron projection development; GO:0050808 synapse organization; GO:0030182 neuron differentiation; GO:0061564 axon development; GO:0055085 transmembrane transport; GO:0006873 cellular ion homeostasis; GO:0006811 ion transport; GO:0044767 single-organism developmental process; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0042692 muscle cell differentiation; GO:0010467 gene expression; GO:0006875 cellular metal ion homeostasis; GO:0051604 protein maturation; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0070838 divalent metal ion transport; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0098800 inner mitochondrial membrane protein complex; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0031305 integral component of mitochondrial inner membrane; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0031304 intrinsic component of mitochondrial inner membrane; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:1902494 catalytic complex; GO:0031301 integral component of organelle membrane; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0019866 organelle inner membrane; GO:1905368 peptidase complex; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0043229 intracellular organelle; GO:0098573 intrinsic component of mitochondrial membrane; GO:0044429 mitochondrial part; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0016021 integral component of membrane; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031975 envelope; GO:0005745 m-AAA complex; GO:0032592 integral component of mitochondrial membrane; GO:0043234 protein complex; GO:0031966 mitochondrial membrane; GO:0031300 intrinsic component of organelle membrane; GO:0044444 cytoplasmic part; ","GO:0008233 peptidase activity; GO:1901265 nucleoside phosphate binding; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0004222 metalloendopeptidase activity; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0008237 metallopeptidase activity; GO:0000166 nucleotide binding; GO:0008270 zinc ion binding; GO:0004175 endopeptidase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0046914 transition metal ion binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0046872 metal ion binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0051082 unfolded protein binding; GO:0036094 small molecule binding; ","K08956",null,null,"IPR003593; IPR003959; IPR011546; IPR000642; IPR027417; ","\"AAA+ ATPase domain; ATPase, AAA-type, core; Peptidase M41, FtsH extracellular; Peptidase M41; P-loop containing nucleoside triphosphate hydrolase; \"\r"]
["Q9Y4Z0","U6 snRNA-associated Sm-like protein LSm4 OS=Homo sapiens OX=9606 GN=LSM4","LSM4",15.35,7.2737,20.9,3,6,3,1.018,0.991,0.981,1.032,1.011,1,1.018,0.288,"cyto_nucl\r","GO:0044085 cellular component biogenesis; GO:0022613 ribonucleoprotein complex biogenesis; GO:0022618 ribonucleoprotein complex assembly; GO:0044237 cellular metabolic process; GO:0008152 metabolic process; GO:0071826 ribonucleoprotein complex subunit organization; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:1901361 organic cyclic compound catabolic process; GO:0043170 macromolecule metabolic process; GO:0006396 RNA processing; GO:0010468 regulation of gene expression; GO:1901360 organic cyclic compound metabolic process; GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic; GO:0010605 negative regulation of macromolecule metabolic process; GO:0006397 mRNA processing; GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; GO:0016070 RNA metabolic process; GO:0006401 RNA catabolic process; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0050789 regulation of biological process; GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; GO:0090304 nucleic acid metabolic process; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0016071 mRNA metabolic process; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0048519 negative regulation of biological process; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0070925 organelle assembly; GO:0000375 RNA splicing, via transesterification reactions; GO:0044248 cellular catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0033962 cytoplasmic mRNA processing body assembly; GO:0009987 cellular process; GO:0008380 RNA splicing; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0034622 cellular macromolecular complex assembly; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0006807 nitrogen compound metabolic process; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0006996 organelle organization; GO:0009057 macromolecule catabolic process; GO:0010467 gene expression; GO:0009056 catabolic process; GO:0000245 spliceosomal complex assembly; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; GO:0000387 spliceosomal snRNP assembly; ","GO:0000932 P-body; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0036464 cytoplasmic ribonucleoprotein granule; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0097526 spliceosomal tri-snRNP complex; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005681 spliceosomal complex; GO:0005829 cytosol; GO:0097525 spliceosomal snRNP complex; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0035770 ribonucleoprotein granule; GO:1990904 ribonucleoprotein complex; GO:0005688 U6 snRNP; GO:0030529 intracellular ribonucleoprotein complex; GO:0030532 small nuclear ribonucleoprotein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0017070 U6 snRNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0017069 snRNA binding; ","K12623","LSM4; U6 snRNA-associated Sm-like protein LSm4","hsa03018 RNA degradation - Homo sapiens (human); hsa03040 Spliceosome - Homo sapiens (human); ","IPR034101; IPR001163; IPR010920; ","\"Sm-like protein Lsm4; LSM domain, eukaryotic/archaea-type; LSM domain; \"\r"]
["Q9Y512","Sorting and assembly machinery component 50 homolog OS=Homo sapiens OX=9606 GN=SAMM50","SAMM50",51.976,35.206,17.1,7,8,7,0.974,0.929,1.045,1.026,1.013,1.017,1.037,0.393,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0042407 cristae formation; GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0072594 establishment of protein localization to organelle; GO:0007006 mitochondrial membrane organization; GO:0017038 protein import; GO:0006839 mitochondrial transport; GO:0044699 single-organism process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0045040 protein import into mitochondrial outer membrane; GO:0051649 establishment of localization in cell; GO:1902578 single-organism localization; GO:0022607 cellular component assembly; GO:0090151 establishment of protein localization to mitochondrial membrane; GO:0065003 macromolecular complex assembly; GO:1990542 mitochondrial transmembrane transport; GO:0007005 mitochondrion organization; GO:0006886 intracellular protein transport; GO:0065002 intracellular protein transmembrane transport; GO:0006626 protein targeting to mitochondrion; GO:1902580 single-organism cellular localization; GO:0033365 protein localization to organelle; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0044743 protein transmembrane import into intracellular organelle; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0090150 establishment of protein localization to membrane; GO:0006461 protein complex assembly; GO:0043623 cellular protein complex assembly; GO:0044765 single-organism transport; GO:0034622 cellular macromolecular complex assembly; GO:0071822 protein complex subunit organization; GO:0072657 protein localization to membrane; GO:0071806 protein transmembrane transport; GO:0044763 single-organism cellular process; GO:0044802 single-organism membrane organization; GO:0071702 organic substance transport; GO:0070585 protein localization to mitochondrion; GO:1902582 single-organism intracellular transport; GO:0043933 macromolecular complex subunit organization; GO:0051641 cellular localization; GO:0007007 inner mitochondrial membrane organization; GO:0006810 transport; GO:0045184 establishment of protein localization; GO:1902589 single-organism organelle organization; GO:0055085 transmembrane transport; GO:0070727 cellular macromolecule localization; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0070271 protein complex biogenesis; GO:0051179 localization; GO:0072655 establishment of protein localization to mitochondrion; GO:0033108 mitochondrial respiratory chain complex assembly; GO:0007008 outer mitochondrial membrane organization; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0019867 outer membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0032991 macromolecular complex; GO:0098798 mitochondrial protein complex; GO:0044424 intracellular part; GO:0044455 mitochondrial membrane part; GO:0005623 cell; GO:0044422 organelle part; GO:0005740 mitochondrial envelope; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0019866 organelle inner membrane; GO:1903561 extracellular vesicle; GO:0031968 organelle outer membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0098799 outer mitochondrial membrane protein complex; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0044429 mitochondrial part; GO:0005741 mitochondrial outer membrane; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031975 envelope; GO:0001401 mitochondrial sorting and assembly machinery complex; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ","K07277",null,null,"IPR000184; ","Bacterial surface antigen (D15); \r"]
["Q9Y520","Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C","PRRC2C",316.91,4.8434,0.9,3,3,3,0.78,0.804,0.89,1.193,1.196,1.09,1.406,0.00244,"nucleus\r","GO:0032502 developmental process; GO:0002244 hematopoietic progenitor cell differentiation; GO:0044707 single-multicellular organism process; GO:0048731 system development; GO:0048869 cellular developmental process; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0002520 immune system development; GO:0002376 immune system process; GO:0032501 multicellular organismal process; GO:0048534 hematopoietic or lymphoid organ development; GO:0030097 hemopoiesis; GO:0030154 cell differentiation; GO:0048513 animal organ development; GO:0044767 single-organism developmental process; GO:0007275 multicellular organism development; GO:0048856 anatomical structure development; GO:0009987 cellular process; ","GO:0016020 membrane; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0008022 protein C-terminus binding; ",{"$nulls":3},"IPR009738; ","\"BAT2, N-terminal; \"\r"]
["Q9Y570","Protein phosphatase methylesterase 1 OS=Homo sapiens OX=9606 GN=PPME1","PPME1",42.315,13.246,14.5,4,5,4,1.162,0.966,0.981,0.971,0.965,0.97,0.935,0.393,"nucleus\r","GO:0070988 demethylation; GO:0044763 single-organism cellular process; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0043086 negative regulation of catalytic activity; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:0008214 protein dealkylation; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0006482 protein demethylation; GO:0044260 cellular macromolecule metabolic process; GO:0065009 regulation of molecular function; GO:0044092 negative regulation of molecular function; GO:0006464 cellular protein modification process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:0009987 cellular process; GO:0065007 biological regulation; ",null,"GO:0052689 carboxylic ester hydrolase activity; GO:0019903 protein phosphatase binding; GO:0019888 protein phosphatase regulator activity; GO:0019901 protein kinase binding; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0019900 kinase binding; GO:0098772 molecular function regulator; GO:0004857 enzyme inhibitor activity; GO:0051721 protein phosphatase 2A binding; GO:0050839 cell adhesion molecule binding; GO:0004864 protein phosphatase inhibitor activity; GO:0051722 protein C-terminal methylesterase activity; GO:0030234 enzyme regulator activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0019208 phosphatase regulator activity; GO:0051723 protein methylesterase activity; GO:0045296 cadherin binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0019902 phosphatase binding; GO:0019899 enzyme binding; GO:0019212 phosphatase inhibitor activity; ","K13617",null,null,"IPR029058; IPR000073; ","Alpha/Beta hydrolase fold; Alpha/beta hydrolase fold-1; \r"]
["Q9Y5B9","FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H","SUPT16H",119.91,6.4745,3,3,3,3,0.906,0.769,0.989,1.227,1.054,1.05,1.25,0.0655,"nucleus\r","GO:0097659 nucleic acid-templated transcription; GO:0023051 regulation of signaling; GO:0009891 positive regulation of biosynthetic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0006354 DNA-templated transcription, elongation; GO:0044237 cellular metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0010646 regulation of cell communication; GO:0034724 DNA replication-independent nucleosome organization; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0032784 regulation of DNA-templated transcription, elongation; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0043170 macromolecule metabolic process; GO:0071824 protein-DNA complex subunit organization; GO:0006333 chromatin assembly or disassembly; GO:0051716 cellular response to stimulus; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0031498 chromatin disassembly; GO:0045893 positive regulation of transcription, DNA-templated; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0032786 positive regulation of DNA-templated transcription, elongation; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0048583 regulation of response to stimulus; GO:0006337 nucleosome disassembly; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006325 chromatin organization; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0034728 nucleosome organization; GO:0033554 cellular response to stress; GO:0006260 DNA replication; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0006259 DNA metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0010628 positive regulation of gene expression; GO:1901796 regulation of signal transduction by p53 class mediator; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0009059 macromolecule biosynthetic process; GO:0009966 regulation of signal transduction; GO:0009987 cellular process; GO:0032986 protein-DNA complex disassembly; GO:0051254 positive regulation of RNA metabolic process; GO:1902531 regulation of intracellular signal transduction; GO:0006355 regulation of transcription, DNA-templated; GO:0006950 response to stress; GO:0006368 transcription elongation from RNA polymerase II promoter; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0032984 macromolecular complex disassembly; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0006974 cellular response to DNA damage stimulus; GO:0044249 cellular biosynthetic process; GO:0043933 macromolecular complex subunit organization; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0034243 regulation of transcription elongation from RNA polymerase II promoter; GO:0006281 DNA repair; GO:0051276 chromosome organization; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0006366 transcription from RNA polymerase II promoter; GO:0022411 cellular component disassembly; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0010467 gene expression; GO:0031328 positive regulation of cellular biosynthetic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0032991 macromolecular complex; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031974 membrane-enclosed lumen; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0035101 FACT complex; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0008023 transcription elongation factor complex; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0042393 histone binding; GO:0003723 RNA binding; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0003676 nucleic acid binding; GO:0031491 nucleosome binding; GO:0005515 protein binding; GO:0003682 chromatin binding; ",{"$nulls":3},"IPR033825; IPR013719; IPR029149; IPR000994; IPR000640; IPR029148; IPR013953; ","\"FACT complex subunit SPT16; Domain of unknown function DUF1747; Creatinase/Aminopeptidase P/Spt16, N-terminal; Peptidase M24; Translation elongation factor EFG, V domain; FACT complex subunit Spt16, N-terminal lobe domain; FACT complex subunit Spt16p/Cdc68p; \"\r"]
["Q9Y5J7","Mitochondrial import inner membrane translocase subunit Tim9 OS=Homo sapiens OX=9606 GN=TIMM9","TIMM9",10.378,16.562,29.2,2,2,2,0.947,0.89,0.978,1.115,1.024,1.047,1.132,0.0301,"extracellular\r","GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0072594 establishment of protein localization to organelle; GO:0007006 mitochondrial membrane organization; GO:0017038 protein import; GO:0006839 mitochondrial transport; GO:0044699 single-organism process; GO:0050877 neurological system process; GO:0015031 protein transport; GO:0045039 protein import into mitochondrial inner membrane; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0051649 establishment of localization in cell; GO:1902578 single-organism localization; GO:0090151 establishment of protein localization to mitochondrial membrane; GO:0007005 mitochondrion organization; GO:1990542 mitochondrial transmembrane transport; GO:0006886 intracellular protein transport; GO:0065002 intracellular protein transmembrane transport; GO:0006626 protein targeting to mitochondrion; GO:1902580 single-organism cellular localization; GO:0033365 protein localization to organelle; GO:0044743 protein transmembrane import into intracellular organelle; GO:0034613 cellular protein localization; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0009987 cellular process; GO:0090150 establishment of protein localization to membrane; GO:0072321 chaperone-mediated protein transport; GO:0044765 single-organism transport; GO:0007600 sensory perception; GO:0003008 system process; GO:0072657 protein localization to membrane; GO:0044763 single-organism cellular process; GO:0071806 protein transmembrane transport; GO:0044802 single-organism membrane organization; GO:0071702 organic substance transport; GO:0070585 protein localization to mitochondrion; GO:0032501 multicellular organismal process; GO:1902582 single-organism intracellular transport; GO:0051641 cellular localization; GO:0007007 inner mitochondrial membrane organization; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:1902589 single-organism organelle organization; GO:0055085 transmembrane transport; GO:0070727 cellular macromolecule localization; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0007605 sensory perception of sound; GO:0051179 localization; GO:0072655 establishment of protein localization to mitochondrion; GO:0050954 sensory perception of mechanical stimulus; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044429 mitochondrial part; GO:0031090 organelle membrane; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0042719 mitochondrial intermembrane space protein transporter complex; GO:0031974 membrane-enclosed lumen; GO:0005740 mitochondrial envelope; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031970 organelle envelope lumen; GO:0070013 intracellular organelle lumen; GO:0005758 mitochondrial intermembrane space; GO:0005622 intracellular; GO:0044464 cell part; GO:0031975 envelope; GO:0019866 organelle inner membrane; GO:1990351 transporter complex; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0031966 mitochondrial membrane; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; ","GO:0042802 identical protein binding; GO:0046914 transition metal ion binding; GO:0051087 chaperone binding; GO:0042803 protein homodimerization activity; GO:0005488 binding; GO:0046983 protein dimerization activity; GO:0043167 ion binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005515 protein binding; GO:0008270 zinc ion binding; GO:0005215 transporter activity; ","K17777",null,null,"IPR004217; ","Tim10/DDP family zinc finger; \r"]
["Q9Y5K5","Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5","UCHL5",37.606,13.414,17.3,5,8,5,0.9,1.117,0.863,1.039,1.035,1.053,1.086,0.383,"cytoplasm\r","GO:0070646 protein modification by small protein removal; GO:0048853 forebrain morphogenesis; GO:0097659 nucleic acid-templated transcription; GO:0007420 brain development; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0021537 telencephalon development; GO:2001141 regulation of RNA biosynthetic process; GO:0010466 negative regulation of peptidase activity; GO:0008152 metabolic process; GO:0060322 head development; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:1903362 regulation of cellular protein catabolic process; GO:0006310 DNA recombination; GO:0052548 regulation of endopeptidase activity; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0030901 midbrain development; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0070647 protein modification by small protein conjugation or removal; GO:0043086 negative regulation of catalytic activity; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0016070 RNA metabolic process; GO:1901575 organic substance catabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0048513 animal organ development; GO:0021670 lateral ventricle development; GO:0048854 brain morphogenesis; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0090304 nucleic acid metabolic process; GO:0051336 regulation of hydrolase activity; GO:0006351 transcription, DNA-templated; GO:0030163 protein catabolic process; GO:0007417 central nervous system development; GO:0050790 regulation of catalytic activity; GO:0032269 negative regulation of cellular protein metabolic process; GO:0061136 regulation of proteasomal protein catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0009887 animal organ morphogenesis; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0006464 cellular protein modification process; GO:0044092 negative regulation of molecular function; GO:0036211 protein modification process; GO:0052547 regulation of peptidase activity; GO:0048856 anatomical structure development; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0033554 cellular response to stress; GO:0044707 single-multicellular organism process; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0010951 negative regulation of endopeptidase activity; GO:0044257 cellular protein catabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0006259 DNA metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044267 cellular protein metabolic process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0016579 protein deubiquitination; GO:0051346 negative regulation of hydrolase activity; GO:0071704 organic substance metabolic process; GO:0009653 anatomical structure morphogenesis; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0021591 ventricular system development; GO:0009889 regulation of biosynthetic process; GO:0044248 cellular catabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0030900 forebrain development; GO:0006508 proteolysis; GO:0042176 regulation of protein catabolic process; GO:0007275 multicellular organism development; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0043632 modification-dependent macromolecule catabolic process; GO:1903050 regulation of proteolysis involved in cellular protein catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0045861 negative regulation of proteolysis; GO:0006355 regulation of transcription, DNA-templated; GO:0006950 response to stress; GO:0019941 modification-dependent protein catabolic process; GO:0048731 system development; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0030162 regulation of proteolysis; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0009892 negative regulation of metabolic process; GO:0044249 cellular biosynthetic process; GO:0006974 cellular response to DNA damage stimulus; GO:0006281 DNA repair; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0009057 macromolecule catabolic process; GO:0051248 negative regulation of protein metabolic process; GO:0010467 gene expression; GO:0043412 macromolecule modification; GO:0009056 catabolic process; GO:0065007 biological regulation; ","GO:0005737 cytoplasm; GO:0097346 INO80-type complex; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0070603 SWI/SNF superfamily-type complex; GO:0005623 cell; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:1905369 endopeptidase complex; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044454 nuclear chromosome part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005694 chromosome; GO:0000790 nuclear chromatin; GO:0044445 cytosolic part; GO:1905368 peptidase complex; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0033202 DNA helicase complex; GO:0000502 proteasome complex; GO:0043232 intracellular non-membrane-bounded organelle; GO:0031011 Ino80 complex; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005829 cytosol; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0000785 chromatin; GO:0031597 cytosolic proteasome complex; GO:0000228 nuclear chromosome; GO:0043234 protein complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0004843 thiol-dependent ubiquitin-specific protease activity; GO:0003723 RNA binding; GO:0008233 peptidase activity; GO:0061134 peptidase regulator activity; GO:0044877 macromolecular complex binding; GO:0019783 ubiquitin-like protein-specific protease activity; GO:0016787 hydrolase activity; GO:0008234 cysteine-type peptidase activity; GO:0005515 protein binding; GO:0098772 molecular function regulator; GO:0004857 enzyme inhibitor activity; GO:0070628 proteasome binding; GO:0004866 endopeptidase inhibitor activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0030234 enzyme regulator activity; GO:0036459 thiol-dependent ubiquitinyl hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0030414 peptidase inhibitor activity; GO:0003676 nucleic acid binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0101005 ubiquitinyl hydrolase activity; GO:0061135 endopeptidase regulator activity; GO:0032403 protein complex binding; ","K05610",null,null,"IPR033837; IPR001578; ","\"Ubiquitinyl hydrolase-L5; Peptidase C12, ubiquitin carboxyl-terminal hydrolase; \"\r"]
["Q9Y5K6","CD2-associated protein OS=Homo sapiens OX=9606 GN=CD2AP","CD2AP",71.45,5.9221,4.1,3,4,3,1.017,0.983,1.02,1.008,0.996,0.985,0.99,0.494,"nucleus\r","GO:0060627 regulation of vesicle-mediated transport; GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0051674 localization of cell; GO:0007067 mitotic nuclear division; GO:0051241 negative regulation of multicellular organismal process; GO:0044699 single-organism process; GO:0032911 negative regulation of transforming growth factor beta1 production; GO:0001818 negative regulation of cytokine production; GO:0044237 cellular metabolic process; GO:0022610 biological adhesion; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0016337 single organismal cell-cell adhesion; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0032879 regulation of localization; GO:0065003 macromolecular complex assembly; GO:0007155 cell adhesion; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0051493 regulation of cytoskeleton organization; GO:0006929 substrate-dependent cell migration; GO:0006930 substrate-dependent cell migration, cell extension; GO:0051716 cellular response to stimulus; GO:0000278 mitotic cell cycle; GO:0071822 protein complex subunit organization; GO:0048259 regulation of receptor-mediated endocytosis; GO:0044763 single-organism cellular process; GO:0098609 cell-cell adhesion; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0048870 cell motility; GO:0023052 signaling; GO:1901575 organic substance catabolic process; GO:0050789 regulation of biological process; GO:0030030 cell projection organization; GO:0030163 protein catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:1900180 regulation of protein localization to nucleus; GO:0098602 single organism cell adhesion; GO:0032908 regulation of transforming growth factor beta1 production; GO:0051301 cell division; GO:0040011 locomotion; GO:0070271 protein complex biogenesis; GO:0050794 regulation of cellular process; GO:0016477 cell migration; GO:0016043 cellular component organization; GO:0051603 proteolysis involved in cellular protein catabolic process; GO:0044257 cellular protein catabolic process; GO:1903829 positive regulation of cellular protein localization; GO:0032956 regulation of actin cytoskeleton organization; GO:0048285 organelle fission; GO:0044267 cellular protein metabolic process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:1903047 mitotic cell cycle process; GO:0010498 proteasomal protein catabolic process; GO:0051239 regulation of multicellular organismal process; GO:0071704 organic substance metabolic process; GO:0060341 regulation of cellular localization; GO:2000249 regulation of actin cytoskeleton reorganization; GO:0044248 cellular catabolic process; GO:0006508 proteolysis; GO:0032880 regulation of protein localization; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0043632 modification-dependent macromolecule catabolic process; GO:0044265 cellular macromolecule catabolic process; GO:0071634 regulation of transforming growth factor beta production; GO:0030100 regulation of endocytosis; GO:0019941 modification-dependent protein catabolic process; GO:0051049 regulation of transport; GO:0016050 vesicle organization; GO:0033043 regulation of organelle organization; GO:0032970 regulation of actin filament-based process; GO:0044238 primary metabolic process; GO:0048518 positive regulation of biological process; GO:0030031 cell projection assembly; GO:0043933 macromolecular complex subunit organization; GO:1900182 positive regulation of protein localization to nucleus; GO:0006996 organelle organization; GO:0009057 macromolecule catabolic process; GO:0071635 negative regulation of transforming growth factor beta production; GO:0001817 regulation of cytokine production; GO:0006928 movement of cell or subcellular component; GO:0000280 nuclear division; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0022402 cell cycle process; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0009056 catabolic process; GO:1903827 regulation of cellular protein localization; GO:0007049 cell cycle; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0005911 cell-cell junction; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0005884 actin filament; GO:0030139 endocytic vesicle; GO:0043227 membrane-bounded organelle; GO:0031941 filamentous actin; GO:0031252 cell leading edge; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0042995 cell projection; GO:0099513 polymeric cytoskeletal fiber; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0005576 extracellular region; GO:0015629 actin cytoskeleton; GO:0005886 plasma membrane; GO:0099081 supramolecular polymer; GO:0043226 organelle; GO:0001726 ruffle; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005102 receptor binding; GO:0044877 macromolecular complex binding; GO:0005126 cytokine receptor binding; GO:0070851 growth factor receptor binding; GO:0005515 protein binding; GO:0005172 vascular endothelial growth factor receptor binding; GO:0017124 SH3 domain binding; GO:0050839 cell adhesion molecule binding; GO:0005200 structural constituent of cytoskeleton; GO:0005488 binding; GO:0045296 cadherin binding; GO:0008022 protein C-terminus binding; GO:0019904 protein domain specific binding; GO:0005198 structural molecule activity; GO:0032403 protein complex binding; GO:0008013 beta-catenin binding; ","K13738","CD2AP; CD2-associated protein","hsa05100 Bacterial invasion of epithelial cells - Homo sapiens (human); ","IPR001452; ","SH3 domain; \r"]
["Q9Y5K8","V-type proton ATPase subunit D OS=Homo sapiens OX=9606 GN=ATP6V1D","ATP6V1D",28.262,28.59,25.5,6,8,6,0.921,1.003,0.882,1.079,1.097,1.008,1.135,0.05,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0044700 single organism signaling; GO:0065008 regulation of biological quality; GO:0008286 insulin receptor signaling pathway; GO:0045321 leukocyte activation; GO:0007166 cell surface receptor signaling pathway; GO:0060271 cilium assembly; GO:0030641 regulation of cellular pH; GO:0030004 cellular monovalent inorganic cation homeostasis; GO:0044699 single-organism process; GO:0015031 protein transport; GO:0044782 cilium organization; GO:0051234 establishment of localization; GO:0000041 transition metal ion transport; GO:0007165 signal transduction; GO:1901653 cellular response to peptide; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0009719 response to endogenous stimulus; GO:0033365 protein localization to organelle; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:1901652 response to peptide; GO:0070887 cellular response to chemical stimulus; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0051716 cellular response to stimulus; GO:0002443 leukocyte mediated immunity; GO:0050801 ion homeostasis; GO:0015682 ferric iron transport; GO:0090383 phagosome acidification; GO:0031329 regulation of cellular catabolic process; GO:0009894 regulation of catabolic process; GO:0002446 neutrophil mediated immunity; GO:0098771 inorganic ion homeostasis; GO:0044763 single-organism cellular process; GO:0019725 cellular homeostasis; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0031323 regulation of cellular metabolic process; GO:0033572 transferrin transport; GO:0023052 signaling; GO:0010506 regulation of autophagy; GO:0002444 myeloid leukocyte mediated immunity; GO:0016241 regulation of macroautophagy; GO:0006810 transport; GO:0071417 cellular response to organonitrogen compound; GO:1902589 single-organism organelle organization; GO:0010243 response to organonitrogen compound; GO:0050789 regulation of biological process; GO:0032868 response to insulin; GO:0042221 response to chemical; GO:0043434 response to peptide hormone; GO:0030030 cell projection organization; GO:1901699 cellular response to nitrogen compound; GO:0032940 secretion by cell; GO:0032870 cellular response to hormone stimulus; GO:1901698 response to nitrogen compound; GO:0032869 cellular response to insulin stimulus; GO:0019222 regulation of metabolic process; GO:0043299 leukocyte degranulation; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0002283 neutrophil activation involved in immune response; GO:0034220 ion transmembrane transport; GO:0045851 pH reduction; GO:0006885 regulation of pH; GO:0002252 immune effector process; GO:0061512 protein localization to cilium; GO:0030001 metal ion transport; GO:0071310 cellular response to organic substance; GO:0030003 cellular cation homeostasis; GO:1901700 response to oxygen-containing compound; GO:0006826 iron ion transport; GO:0050896 response to stimulus; GO:0055082 cellular chemical homeostasis; GO:0042592 homeostatic process; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0006812 cation transport; GO:0070925 organelle assembly; GO:0055080 cation homeostasis; GO:0071375 cellular response to peptide hormone stimulus; GO:0036230 granulocyte activation; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0090382 phagosome maturation; GO:0055067 monovalent inorganic cation homeostasis; GO:0016192 vesicle-mediated transport; GO:0071702 organic substance transport; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0043312 neutrophil degranulation; GO:0002263 cell activation involved in immune response; GO:0006818 hydrogen transport; GO:0015992 proton transport; GO:0030031 cell projection assembly; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0072512 trivalent inorganic cation transport; GO:0002366 leukocyte activation involved in immune response; GO:0055085 transmembrane transport; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:0070727 cellular macromolecule localization; GO:1901701 cellular response to oxygen-containing compound; GO:0051453 regulation of intracellular pH; GO:0006873 cellular ion homeostasis; GO:0071495 cellular response to endogenous stimulus; GO:0006811 ion transport; GO:0006996 organelle organization; GO:0001775 cell activation; GO:0051452 intracellular pH reduction; GO:0006955 immune response; GO:0009725 response to hormone; GO:0051179 localization; GO:0015672 monovalent inorganic cation transport; GO:0006887 exocytosis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0033176 proton-transporting V-type ATPase complex; GO:0005623 cell; GO:0044422 organelle part; GO:0005765 lysosomal membrane; GO:0070062 extracellular exosome; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0098805 whole membrane; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0035579 specific granule membrane; GO:0000323 lytic vacuole; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0098852 lytic vacuole membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0030667 secretory granule membrane; GO:0042581 specific granule; GO:0044437 vacuolar part; GO:0016469 proton-transporting two-sector ATPase complex; GO:0005773 vacuole; GO:0005774 vacuolar membrane; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0022804 active transmembrane transporter activity; GO:0015399 primary active transmembrane transporter activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0017111 nucleoside-triphosphatase activity; GO:0016887 ATPase activity; GO:0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity; GO:0016462 pyrophosphatase activity; GO:0042626 ATPase activity, coupled to transmembrane movement of substances; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043492 ATPase activity, coupled to movement of substances; GO:0042623 ATPase activity, coupled; GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; ","K02149","ATPeV1D; V-type H+-transporting ATPase subunit D","hsa05120 Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human); hsa04966 Collecting duct acid secretion - Homo sapiens (human); hsa05323 Rheumatoid arthritis - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa04150 mTOR signaling pathway - Homo sapiens (human); hsa00190 Oxidative phosphorylation - Homo sapiens (human); hsa05110 Vibrio cholerae infection - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); hsa04721 Synaptic vesicle cycle - Homo sapiens (human); "]
["Q9Y5L0","Transportin-3 OS=Homo sapiens OX=9606 GN=TNPO3","TNPO3",104.2,25.603,10.2,7,7,7,0.987,0.964,0.794,1.039,1.107,1.11,1.186,0.0727,"cytoplasm\r","GO:0046907 intracellular transport; GO:0072594 establishment of protein localization to organelle; GO:0035048 splicing factor protein import into nucleus; GO:0017038 protein import; GO:1902593 single-organism nuclear import; GO:0044699 single-organism process; GO:0071702 organic substance transport; GO:0051169 nuclear transport; GO:0015031 protein transport; GO:1902582 single-organism intracellular transport; GO:0051641 cellular localization; GO:0051234 establishment of localization; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:0006605 protein targeting; GO:0070727 cellular macromolecule localization; GO:0051649 establishment of localization in cell; GO:1902578 single-organism localization; GO:0051170 nuclear import; GO:0006886 intracellular protein transport; GO:0044744 protein targeting to nucleus; GO:0006913 nucleocytoplasmic transport; GO:1902580 single-organism cellular localization; GO:0033365 protein localization to organelle; GO:0034613 cellular protein localization; GO:0006606 protein import into nucleus; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0051179 localization; GO:0034504 protein localization to nucleus; GO:0044765 single-organism transport; ","GO:0016020 membrane; GO:0043229 intracellular organelle; GO:0031090 organelle membrane; GO:0005635 nuclear envelope; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031965 nuclear membrane; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:0031975 envelope; GO:0043227 membrane-bounded organelle; GO:0044428 nuclear part; ","GO:0005048 signal sequence binding; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0008565 protein transporter activity; GO:0042802 identical protein binding; GO:0042277 peptide binding; GO:0005488 binding; GO:0008139 nuclear localization sequence binding; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0033218 amide binding; GO:0005215 transporter activity; ","K15436",null,null,"IPR013598; IPR011989; IPR016024; ","Exportin-1/Importin-beta-like; Armadillo-like helical; Armadillo-type fold; \r"]
["Q9Y5L4","Mitochondrial import inner membrane translocase subunit Tim13 OS=Homo sapiens OX=9606 GN=TIMM13","TIMM13",10.5,23.05,26.3,2,3,2,0.858,0.886,0.945,1.176,1.045,1.086,1.23,0.01,"extracellular\r","GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0072594 establishment of protein localization to organelle; GO:0007006 mitochondrial membrane organization; GO:0017038 protein import; GO:0006839 mitochondrial transport; GO:0044699 single-organism process; GO:0050877 neurological system process; GO:0015031 protein transport; GO:0045039 protein import into mitochondrial inner membrane; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0051649 establishment of localization in cell; GO:1902578 single-organism localization; GO:0090151 establishment of protein localization to mitochondrial membrane; GO:1990542 mitochondrial transmembrane transport; GO:0007005 mitochondrion organization; GO:0065002 intracellular protein transmembrane transport; GO:0006886 intracellular protein transport; GO:0006626 protein targeting to mitochondrion; GO:1902580 single-organism cellular localization; GO:0033365 protein localization to organelle; GO:0044743 protein transmembrane import into intracellular organelle; GO:0034613 cellular protein localization; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0090150 establishment of protein localization to membrane; GO:0009987 cellular process; GO:0072321 chaperone-mediated protein transport; GO:0044765 single-organism transport; GO:0007600 sensory perception; GO:0003008 system process; GO:0072657 protein localization to membrane; GO:0044763 single-organism cellular process; GO:0071806 protein transmembrane transport; GO:0044802 single-organism membrane organization; GO:0071702 organic substance transport; GO:0070585 protein localization to mitochondrion; GO:0032501 multicellular organismal process; GO:1902582 single-organism intracellular transport; GO:0051641 cellular localization; GO:0007007 inner mitochondrial membrane organization; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:1902589 single-organism organelle organization; GO:0055085 transmembrane transport; GO:0070727 cellular macromolecule localization; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0007605 sensory perception of sound; GO:0051179 localization; GO:0072655 establishment of protein localization to mitochondrion; GO:0050954 sensory perception of mechanical stimulus; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0042719 mitochondrial intermembrane space protein transporter complex; GO:0043228 non-membrane-bounded organelle; GO:0005740 mitochondrial envelope; GO:0031974 membrane-enclosed lumen; GO:0031970 organelle envelope lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0019866 organelle inner membrane; GO:1990351 transporter complex; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0031981 nuclear lumen; GO:0044452 nucleolar part; GO:0005730 nucleolus; GO:0001650 fibrillar center; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0005758 mitochondrial intermembrane space; GO:0031975 envelope; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0008565 protein transporter activity; GO:0046914 transition metal ion binding; GO:0005488 binding; GO:0043167 ion binding; GO:0022892 substrate-specific transporter activity; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0008270 zinc ion binding; GO:0005215 transporter activity; ","K17781",null,null,"IPR004217; ","Tim10/DDP family zinc finger; \r"]
["Q9Y5M8","Signal recognition particle receptor subunit beta OS=Homo sapiens OX=9606 GN=SRPRB","SRPRB",29.702,52.09,21.8,5,8,5,0.981,0.962,0.94,1.014,1.005,1.026,1.056,0.0162,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0033554 cellular response to stress; GO:0046907 intracellular transport; GO:0072594 establishment of protein localization to organelle; GO:0034976 response to endoplasmic reticulum stress; GO:0035967 cellular response to topologically incorrect protein; GO:0071310 cellular response to organic substance; GO:0044699 single-organism process; GO:0036498 IRE1-mediated unfolded protein response; GO:0006613 cotranslational protein targeting to membrane; GO:0050896 response to stimulus; GO:0030968 endoplasmic reticulum unfolded protein response; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006605 protein targeting; GO:0006612 protein targeting to membrane; GO:0007165 signal transduction; GO:0035966 response to topologically incorrect protein; GO:0051649 establishment of localization in cell; GO:0007154 cell communication; GO:0070972 protein localization to endoplasmic reticulum; GO:0006614 SRP-dependent cotranslational protein targeting to membrane; GO:0006886 intracellular protein transport; GO:0033365 protein localization to organelle; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0090150 establishment of protein localization to membrane; GO:0070887 cellular response to chemical stimulus; GO:0006986 response to unfolded protein; GO:0051716 cellular response to stimulus; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0006950 response to stress; GO:0034620 cellular response to unfolded protein; GO:0072657 protein localization to membrane; GO:0035556 intracellular signal transduction; GO:0071702 organic substance transport; GO:0045047 protein targeting to ER; GO:0007264 small GTPase mediated signal transduction; GO:0010033 response to organic substance; GO:0023052 signaling; GO:0051641 cellular localization; GO:0006810 transport; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0051179 localization; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0030867 rough endoplasmic reticulum membrane; GO:0005874 microtubule; GO:0031090 organelle membrane; GO:0005881 cytoplasmic microtubule; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0044422 organelle part; GO:0005785 signal recognition particle receptor complex; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0015630 microtubule cytoskeleton; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0098588 bounding membrane of organelle; GO:0005791 rough endoplasmic reticulum; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0016021 integral component of membrane; GO:0099081 supramolecular polymer; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044432 endoplasmic reticulum part; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0044877 macromolecular complex binding; GO:0000166 nucleotide binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0005047 signal recognition particle binding; GO:0032550 purine ribonucleoside binding; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0043021 ribonucleoprotein complex binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0036094 small molecule binding; ","K12272","SRPRB; signal recognition particle receptor subunit beta","hsa03060 Protein export - Homo sapiens (human); ","IPR027417; ","P-loop containing nucleoside triphosphate hydrolase; \r"]
["Q9Y5P4","Collagen type IV alpha-3-binding protein OS=Homo sapiens OX=9606 GN=COL4A3BP","COL4A3BP",70.834,13.99,8.8,5,5,5,0.936,0.957,0.978,1.078,1.033,1.025,1.092,0.0119,"nucleus\r","GO:0044700 single organism signaling; GO:0010256 endomembrane system organization; GO:0065008 regulation of biological quality; GO:0003012 muscle system process; GO:0043009 chordate embryonic development; GO:0006643 membrane lipid metabolic process; GO:0048869 cellular developmental process; GO:0006672 ceramide metabolic process; GO:0032989 cellular component morphogenesis; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044255 cellular lipid metabolic process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0008610 lipid biosynthetic process; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0007507 heart development; GO:0032365 intracellular lipid transport; GO:0051649 establishment of localization in cell; GO:0030148 sphingolipid biosynthetic process; GO:0007154 cell communication; GO:0032990 cell part morphogenesis; GO:0007005 mitochondrion organization; GO:0006665 sphingolipid metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009790 embryo development; GO:0033036 macromolecule localization; GO:0042886 amide transport; GO:0055088 lipid homeostasis; GO:0044765 single-organism transport; GO:0006629 lipid metabolic process; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0006869 lipid transport; GO:0003007 heart morphogenesis; GO:0044763 single-organism cellular process; GO:0043603 cellular amide metabolic process; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:1902582 single-organism intracellular transport; GO:0000902 cell morphogenesis; GO:0006810 transport; GO:1902589 single-organism organelle organization; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0001701 in utero embryonic development; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0009887 animal organ morphogenesis; GO:0006464 cellular protein modification process; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0007029 endoplasmic reticulum organization; GO:0072359 circulatory system development; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0016310 phosphorylation; GO:0033554 cellular response to stress; GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0034976 response to endoplasmic reticulum stress; GO:0044267 cellular protein metabolic process; GO:0035621 ER to Golgi ceramide transport; GO:0070584 mitochondrion morphogenesis; GO:1901566 organonitrogen compound biosynthetic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0009653 anatomical structure morphogenesis; GO:0006936 muscle contraction; GO:0006468 protein phosphorylation; GO:1902578 single-organism localization; GO:0034641 cellular nitrogen compound metabolic process; GO:1902580 single-organism cellular localization; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0048878 chemical homeostasis; GO:0046467 membrane lipid biosynthetic process; GO:0003008 system process; GO:0044711 single-organism biosynthetic process; GO:0006950 response to stress; GO:0048731 system development; GO:0009792 embryo development ending in birth or egg hatching; GO:0006807 nitrogen compound metabolic process; GO:0002376 immune system process; GO:0008283 cell proliferation; GO:0071702 organic substance transport; GO:0010876 lipid localization; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0051641 cellular localization; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0044767 single-organism developmental process; GO:0035627 ceramide transport; GO:0006955 immune response; GO:0043412 macromolecule modification; GO:0051179 localization; GO:0071705 nitrogen compound transport; GO:1901564 organonitrogen compound metabolic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0043229 intracellular organelle; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0031974 membrane-enclosed lumen; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0044432 endoplasmic reticulum part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0005794 Golgi apparatus; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:1901981 phosphatidylinositol phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0046625 sphingolipid binding; GO:0043167 ion binding; GO:0005319 lipid transporter activity; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0033218 amide binding; GO:0004672 protein kinase activity; GO:0035620 ceramide transporter activity; GO:0016301 kinase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0046624 sphingolipid transporter activity; GO:0005543 phospholipid binding; GO:0035091 phosphatidylinositol binding; GO:0008289 lipid binding; GO:0043168 anion binding; GO:0070273 phosphatidylinositol-4-phosphate binding; GO:0097001 ceramide binding; GO:0016740 transferase activity; GO:0005215 transporter activity; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K08283",null,null,"IPR011993; IPR002913; IPR023393; IPR001849; ","PH domain-like; START domain; START-like domain; Pleckstrin homology domain; \r"]
["Q9Y5P6","Mannose-1-phosphate guanyltransferase beta OS=Homo sapiens OX=9606 GN=GMPPB","GMPPB",39.834,29.351,10.6,3,4,3,0.962,0.992,1.128,1.003,0.898,1.026,0.95,0.47,"mitochondria\r","GO:0009226 nucleotide-sugar biosynthetic process; GO:0018130 heterocycle biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0009058 biosynthetic process; GO:0044238 primary metabolic process; GO:0044237 cellular metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0019673 GDP-mannose metabolic process; GO:1901137 carbohydrate derivative biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009298 GDP-mannose biosynthetic process; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009225 nucleotide-sugar metabolic process; GO:0009987 cellular process; GO:1901362 organic cyclic compound biosynthetic process; ","GO:0043229 intracellular organelle; GO:0044421 extracellular region part; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0043231 intracellular membrane-bounded organelle; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0008905 mannose-phosphate guanylyltransferase activity; GO:0004475 mannose-1-phosphate guanylyltransferase activity; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016779 nucleotidyltransferase activity; GO:0070568 guanylyltransferase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019001 guanyl nucleotide binding; GO:0005525 GTP binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0036094 small molecule binding; ","K00966","GMPP; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]","hsa00051 Fructose and mannose metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00520 Amino sugar and nucleotide sugar metabolism - Homo sapiens (human); ","IPR005835; IPR029044; ","Nucleotidyl transferase domain; Nucleotide-diphospho-sugar transferases; \r"]
["Q9Y5Q9","General transcription factor 3C polypeptide 3 OS=Homo sapiens OX=9606 GN=GTF3C3","GTF3C3",101.27,3.9718,1.8,1,1,1,0.976,0.988,0.948,0.981,0.97,1.139,1.061,0.346,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0006725 cellular aromatic compound metabolic process; GO:0097659 nucleic acid-templated transcription; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0009058 biosynthetic process; GO:0042797 tRNA transcription from RNA polymerase III promoter; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0006359 regulation of transcription from RNA polymerase III promoter; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0098781 ncRNA transcription; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009303 rRNA transcription; GO:0009987 cellular process; GO:0016072 rRNA metabolic process; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0006355 regulation of transcription, DNA-templated; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0044238 primary metabolic process; GO:0051252 regulation of RNA metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0009304 tRNA transcription; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0006399 tRNA metabolic process; GO:0050789 regulation of biological process; GO:0034645 cellular macromolecule biosynthetic process; GO:0090304 nucleic acid metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006351 transcription, DNA-templated; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0010467 gene expression; GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter; GO:0034660 ncRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0006383 transcription from RNA polymerase III promoter; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0090576 RNA polymerase III transcription factor complex; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0031965 nuclear membrane; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0005635 nuclear envelope; GO:0043232 intracellular non-membrane-bounded organelle; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0031981 nuclear lumen; GO:0005730 nucleolus; GO:0005667 transcription factor complex; GO:0044798 nuclear transcription factor complex; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0000127 transcription factor TFIIIC complex; GO:0031975 envelope; GO:0043234 protein complex; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003677 DNA binding; GO:0005515 protein binding; GO:0005488 binding; GO:0003676 nucleic acid binding; ","K15201",null,null,"IPR011990; IPR013026; ","Tetratricopeptide-like helical domain; Tetratricopeptide repeat-containing domain; \r"]
["Q9Y5S2","Serine/threonine-protein kinase MRCK beta OS=Homo sapiens OX=9606 GN=CDC42BPB","CDC42BPB",194.31,19.887,4.7,8,8,8,1.075,0.977,0.924,1.025,0.993,1.015,1.019,0.668,"nucleus\r","GO:0050794 regulation of cellular process; GO:0044700 single organism signaling; GO:0016310 phosphorylation; GO:0016477 cell migration; GO:0016043 cellular component organization; GO:0051674 localization of cell; GO:0044267 cellular protein metabolic process; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0030036 actin cytoskeleton organization; GO:0006468 protein phosphorylation; GO:0007154 cell communication; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0031032 actomyosin structure organization; GO:0051716 cellular response to stimulus; GO:0035556 intracellular signal transduction; GO:0044763 single-organism cellular process; GO:0007163 establishment or maintenance of cell polarity; GO:0048870 cell motility; GO:0044238 primary metabolic process; GO:0023052 signaling; GO:0031532 actin cytoskeleton reorganization; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0044260 cellular macromolecule metabolic process; GO:0006928 movement of cell or subcellular component; GO:0006464 cellular protein modification process; GO:0040011 locomotion; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:0051179 localization; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0031252 cell leading edge; GO:0044421 extracellular region part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005911 cell-cell junction; GO:0005623 cell; GO:0015629 actin cytoskeleton; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0005886 plasma membrane; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0042641 actomyosin; GO:0043230 extracellular organelle; ","GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0005515 protein binding; GO:0004672 protein kinase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016301 kinase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0017016 Ras GTPase binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0051020 GTPase binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0000287 magnesium ion binding; GO:0031267 small GTPase binding; GO:0017048 Rho GTPase binding; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0046872 metal ion binding; GO:0004674 protein serine/threonine kinase activity; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019899 enzyme binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; GO:0036094 small molecule binding; ","K16307",null,null,"IPR001180; IPR014930; IPR020454; IPR011009; IPR000961; IPR001849; IPR002219; IPR000719; IPR000095; IPR011993; IPR031597; ","\"Citron homology (CNH) domain; Myotonic dystrophy protein kinase, coiled coil; Diacylglycerol/phorbol-ester binding; Protein kinase-like domain; AGC-kinase, C-terminal; Pleckstrin homology domain; Protein kinase C-like, phorbol ester/diacylglycerol-binding domain; Protein kinase domain; CRIB domain; PH domain-like; KELK-motif containing domain; \"\r"]
["Q9Y5S9","RNA-binding protein 8A OS=Homo sapiens OX=9606 GN=RBM8A","RBM8A",19.889,39.939,27,4,7,4,1.058,0.905,0.853,1.181,1.019,1.008,1.139,0.183,"nucleus\r","GO:0050658 RNA transport; GO:0000381 regulation of alternative mRNA splicing, via spliceosome; GO:0010608 posttranscriptional regulation of gene expression; GO:0097659 nucleic acid-templated transcription; GO:0009058 biosynthetic process; GO:0051168 nuclear export; GO:0051169 nuclear transport; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0006353 DNA-templated transcription, termination; GO:0071427 mRNA-containing ribonucleoprotein complex export from nucleus; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0050657 nucleic acid transport; GO:0015931 nucleobase-containing compound transport; GO:1901361 organic cyclic compound catabolic process; GO:0043170 macromolecule metabolic process; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0048024 regulation of mRNA splicing, via spliceosome; GO:0006396 RNA processing; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0050684 regulation of mRNA processing; GO:0031323 regulation of cellular metabolic process; GO:0010605 negative regulation of macromolecule metabolic process; GO:0006611 protein export from nucleus; GO:0071166 ribonucleoprotein complex localization; GO:0006401 RNA catabolic process; GO:0006397 mRNA processing; GO:0016070 RNA metabolic process; GO:0006810 transport; GO:1901575 organic substance catabolic process; GO:0019439 aromatic compound catabolic process; GO:0032268 regulation of cellular protein metabolic process; GO:0050789 regulation of biological process; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0006402 mRNA catabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0006913 nucleocytoplasmic transport; GO:0016071 mRNA metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0031123 RNA 3'-end processing; GO:0046907 intracellular transport; GO:0006725 cellular aromatic compound metabolic process; GO:0031124 mRNA 3'-end processing; GO:0060255 regulation of macromolecule metabolic process; GO:0051028 mRNA transport; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0048519 negative regulation of biological process; GO:0051236 establishment of RNA localization; GO:0071704 organic substance metabolic process; GO:0044270 cellular nitrogen compound catabolic process; GO:0000398 mRNA splicing, via spliceosome; GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0009889 regulation of biosynthetic process; GO:0000375 RNA splicing, via transesterification reactions; GO:0006886 intracellular protein transport; GO:0044248 cellular catabolic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0034655 nucleobase-containing compound catabolic process; GO:0009059 macromolecule biosynthetic process; GO:0034613 cellular protein localization; GO:0008380 RNA splicing; GO:0009987 cellular process; GO:0000956 nuclear-transcribed mRNA catabolic process; GO:0006406 mRNA export from nucleus; GO:0044265 cellular macromolecule catabolic process; GO:0010629 negative regulation of gene expression; GO:0006369 termination of RNA polymerase II transcription; GO:0006403 RNA localization; GO:0006405 RNA export from nucleus; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0071702 organic substance transport; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:1901576 organic substance biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0044249 cellular biosynthetic process; GO:0034248 regulation of cellular amide metabolic process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0043484 regulation of RNA splicing; GO:0070727 cellular macromolecule localization; GO:1903311 regulation of mRNA metabolic process; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0071426 ribonucleoprotein complex export from nucleus; GO:0051246 regulation of protein metabolic process; GO:0006417 regulation of translation; GO:0009057 macromolecule catabolic process; GO:0006366 transcription from RNA polymerase II promoter; GO:0010467 gene expression; GO:0051179 localization; GO:0009056 catabolic process; GO:0071705 nitrogen compound transport; GO:0046700 heterocycle catabolic process; GO:0065007 biological regulation; ","GO:0030425 dendrite; GO:0005737 cytoplasm; GO:0043025 neuronal cell body; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0016604 nuclear body; GO:0005623 cell; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:1902494 catalytic complex; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0016607 nuclear speck; GO:0044464 cell part; GO:0005622 intracellular; GO:0043005 neuron projection; GO:0043227 membrane-bounded organelle; GO:0097458 neuron part; GO:0044451 nucleoplasm part; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0005681 spliceosomal complex; GO:0005829 cytosol; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0036477 somatodendritic compartment; GO:0005634 nucleus; GO:0071013 catalytic step 2 spliceosome; GO:0044297 cell body; GO:1990904 ribonucleoprotein complex; GO:0043234 protein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0035145 exon-exon junction complex; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003729 mRNA binding; GO:0003723 RNA binding; GO:1901265 nucleoside phosphate binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0036094 small molecule binding; ","K12876","RBM8A; RNA-binding protein 8A","hsa03040 Spliceosome - Homo sapiens (human); hsa03015 mRNA surveillance pathway - Homo sapiens (human); hsa03013 RNA transport - Homo sapiens (human); ","IPR033744; IPR000504; IPR012677; ","\"RBM8, RNA recognition motif; RNA recognition motif domain; Nucleotide-binding alpha-beta plait domain; \"\r"]
["Q9Y5U9","Immediate early response 3-interacting protein 1 OS=Homo sapiens OX=9606 GN=IER3IP1","IER3IP1",8.9687,13.339,24.4,1,1,1,0.724,1.738,0.675,0.764,1.393,0.732,0.921,0.941,"plasma membrane\r","GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0010941 regulation of cell death; GO:0016192 vesicle-mediated transport; GO:0043067 regulation of programmed cell death; GO:0048193 Golgi vesicle transport; GO:0051641 cellular localization; GO:0051234 establishment of localization; GO:0006810 transport; GO:0051649 establishment of localization in cell; GO:0050789 regulation of biological process; GO:2000269 regulation of fibroblast apoptotic process; GO:0051179 localization; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0030173 integral component of Golgi membrane; GO:0005623 cell; GO:0044422 organelle part; GO:0031301 integral component of organelle membrane; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0044431 Golgi apparatus part; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0030134 ER to Golgi transport vesicle; GO:0012505 endomembrane system; GO:0030135 coated vesicle; GO:0016021 integral component of membrane; GO:0031228 intrinsic component of Golgi membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044432 endoplasmic reticulum part; GO:0030133 transport vesicle; GO:0005794 Golgi apparatus; GO:0031300 intrinsic component of organelle membrane; GO:0044444 cytoplasmic part; "]
["Q9Y5X2","Sorting nexin-8 OS=Homo sapiens OX=9606 GN=SNX8","SNX8",52.569,12.673,7.1,3,4,3,0.984,1.062,1.037,0.884,0.986,1.054,0.948,0.381,"nucleus\r","GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0016192 vesicle-mediated transport; GO:0048193 Golgi vesicle transport; GO:0016050 vesicle organization; GO:0071702 organic substance transport; GO:0006897 endocytosis; GO:0015031 protein transport; GO:0051641 cellular localization; GO:0051234 establishment of localization; GO:0016197 endosomal transport; GO:0006810 transport; GO:0045184 establishment of protein localization; GO:0070727 cellular macromolecule localization; GO:0051649 establishment of localization in cell; GO:0034498 early endosome to Golgi transport; GO:0042147 retrograde transport, endosome to Golgi; GO:0006996 organelle organization; GO:0006886 intracellular protein transport; GO:0034613 cellular protein localization; GO:0016482 cytosolic transport; GO:0051179 localization; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0009987 cellular process; GO:0071840 cellular component organization or biogenesis; ","GO:0010008 endosome membrane; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0098588 bounding membrane of organelle; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0019898 extrinsic component of membrane; GO:0044446 intracellular organelle part; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044440 endosomal part; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0005829 cytosol; GO:0044422 organelle part; GO:0005769 early endosome; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0005768 endosome; GO:0031901 early endosome membrane; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0042802 identical protein binding; GO:0005488 binding; GO:0035091 phosphatidylinositol binding; GO:0005543 phospholipid binding; GO:0043167 ion binding; GO:0008289 lipid binding; GO:0005515 protein binding; GO:0043168 anion binding; ","K17922",null,null,"IPR001683; ","Phox homologous domain; \r"]
["Q9Y5X3","Sorting nexin-5 OS=Homo sapiens OX=9606 GN=SNX5","SNX5",46.816,58.22,26.2,12,21,12,1.016,1.049,1.005,0.995,0.95,0.974,0.951,0.053,"nucleus\r","GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0046907 intracellular transport; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0051649 establishment of localization in cell; GO:0006886 intracellular protein transport; GO:0016482 cytosolic transport; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0031329 regulation of cellular catabolic process; GO:0016192 vesicle-mediated transport; GO:0009894 regulation of catabolic process; GO:0016050 vesicle organization; GO:0071702 organic substance transport; GO:0006897 endocytosis; GO:0031323 regulation of cellular metabolic process; GO:0006907 pinocytosis; GO:0010506 regulation of autophagy; GO:0051641 cellular localization; GO:0016197 endosomal transport; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:0016241 regulation of macroautophagy; GO:0070727 cellular macromolecule localization; GO:0050789 regulation of biological process; GO:0042147 retrograde transport, endosome to Golgi; GO:0006996 organelle organization; GO:0019222 regulation of metabolic process; GO:0051179 localization; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0030904 retromer complex; GO:0031090 organelle membrane; GO:0019898 extrinsic component of membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0098796 membrane protein complex; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0031234 extrinsic component of cytoplasmic side of plasma membrane; GO:0005623 cell; GO:0009898 cytoplasmic side of plasma membrane; GO:0098562 cytoplasmic side of membrane; GO:0044422 organelle part; GO:0005769 early endosome; GO:0044425 membrane part; GO:0044464 cell part; GO:0005622 intracellular; GO:0098805 whole membrane; GO:0001891 phagocytic cup; GO:0005768 endosome; GO:0031901 early endosome membrane; GO:0043227 membrane-bounded organelle; GO:0070685 macropinocytic cup; GO:0098552 side of membrane; GO:0031252 cell leading edge; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0010008 endosome membrane; GO:0097422 tubular endosome; GO:0042995 cell projection; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0019897 extrinsic component of plasma membrane; GO:0012506 vesicle membrane; GO:0044440 endosomal part; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0031313 extrinsic component of endosome membrane; GO:0001726 ruffle; GO:0031312 extrinsic component of organelle membrane; GO:0030905 retromer, tubulation complex; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:0050839 cell adhesion molecule binding; GO:0034452 dynactin binding; GO:0008092 cytoskeletal protein binding; GO:0046982 protein heterodimerization activity; GO:0005488 binding; GO:0046983 protein dimerization activity; GO:0035091 phosphatidylinositol binding; GO:0005543 phospholipid binding; GO:0043167 ion binding; GO:0045296 cadherin binding; GO:0008289 lipid binding; GO:0043168 anion binding; GO:0005515 protein binding; ","K17920","SNX5_6_32; sorting nexin-5/6/32","hsa04144 Endocytosis - Homo sapiens (human); ","IPR015404; IPR001683; ","\"Sorting nexin Vps5-like, C-terminal; Phox homologous domain; \"\r"]
["Q9Y5Y2","Cytosolic Fe-S cluster assembly factor NUBP2 OS=Homo sapiens OX=9606 GN=NUBP2","NUBP2",28.825,3.7313,7,2,3,2,0.875,1.045,0.924,1.028,1.015,1.115,1.11,0.151,"mitochondria\r","GO:0006790 sulfur compound metabolic process; GO:0044085 cellular component biogenesis; GO:0051188 cofactor biosynthetic process; GO:0016043 cellular component organization; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0044249 cellular biosynthetic process; GO:0051186 cofactor metabolic process; GO:0031163 metallo-sulfur cluster assembly; GO:0008152 metabolic process; GO:0030030 cell projection organization; GO:0022607 cellular component assembly; GO:0016226 iron-sulfur cluster assembly; GO:0009987 cellular process; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0005929 cilium; GO:0000922 spindle pole; GO:0042995 cell projection; GO:0044450 microtubule organizing center part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0005819 spindle; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0043226 organelle; GO:0005856 cytoskeleton; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0005815 microtubule organizing center; GO:0015630 microtubule cytoskeleton; GO:0005813 centrosome; GO:0044464 cell part; GO:0005622 intracellular; GO:0005814 centriole; GO:0043227 membrane-bounded organelle; GO:0031616 spindle pole centrosome; GO:0044444 cytoplasmic part; ","GO:0005524 ATP binding; GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0000166 nucleotide binding; GO:0051539 4 iron, 4 sulfur cluster binding; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0032553 ribonucleotide binding; GO:0051536 iron-sulfur cluster binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032555 purine ribonucleotide binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0001883 purine nucleoside binding; GO:0051540 metal cluster binding; GO:0017076 purine nucleotide binding; GO:0036094 small molecule binding; GO:0035639 purine ribonucleoside triphosphate binding; ",{"$nulls":3},"IPR027417; ","P-loop containing nucleoside triphosphate hydrolase; \r"]
["Q9Y5Y6","Suppressor of tumorigenicity 14 protein OS=Homo sapiens OX=9606 GN=ST14","ST14",94.769,13.275,3,2,2,2,0.871,0.866,0.915,1.044,1.16,1.134,1.259,0.00326,"plasma membrane\r","GO:0001841 neural tube formation; GO:0022414 reproductive process; GO:0031424 keratinization; GO:0035148 tube formation; GO:0043009 chordate embryonic development; GO:0048869 cellular developmental process; GO:0001892 embryonic placenta development; GO:0032989 cellular component morphogenesis; GO:0044699 single-organism process; GO:0009913 epidermal cell differentiation; GO:0008152 metabolic process; GO:0048729 tissue morphogenesis; GO:0044702 single organism reproductive process; GO:0008544 epidermis development; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009790 embryo development; GO:0048598 embryonic morphogenesis; GO:0060671 epithelial cell differentiation involved in embryonic placenta development; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0035295 tube development; GO:0060429 epithelium development; GO:0002064 epithelial cell development; GO:0003006 developmental process involved in reproduction; GO:0043588 skin development; GO:0009888 tissue development; GO:0030216 keratinocyte differentiation; GO:0035239 tube morphogenesis; GO:0001763 morphogenesis of a branching structure; GO:0070268 cornification; GO:0048608 reproductive structure development; GO:0044763 single-organism cellular process; GO:0060669 embryonic placenta morphogenesis; GO:0032501 multicellular organismal process; GO:0000902 cell morphogenesis; GO:0048513 animal organ development; GO:0001701 in utero embryonic development; GO:0048856 anatomical structure development; GO:0030855 epithelial cell differentiation; GO:0000003 reproduction; GO:0044707 single-multicellular organism process; GO:0002009 morphogenesis of an epithelium; GO:0016043 cellular component organization; GO:0001890 placenta development; GO:0048568 embryonic organ development; GO:0060711 labyrinthine layer development; GO:0021915 neural tube development; GO:0048468 cell development; GO:0000904 cell morphogenesis involved in differentiation; GO:0060672 epithelial cell morphogenesis involved in placental branching; GO:0071704 organic substance metabolic process; GO:0072175 epithelial tube formation; GO:0009653 anatomical structure morphogenesis; GO:0060606 tube closure; GO:0030154 cell differentiation; GO:0006508 proteolysis; GO:0016331 morphogenesis of embryonic epithelium; GO:0007275 multicellular organism development; GO:0061458 reproductive system development; GO:0001843 neural tube closure; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0009987 cellular process; GO:0060562 epithelial tube morphogenesis; GO:0048731 system development; GO:0009792 embryo development ending in birth or egg hatching; GO:0044238 primary metabolic process; GO:0014020 primary neural tube formation; GO:0001838 embryonic epithelial tube formation; GO:0060713 labyrinthine layer morphogenesis; GO:0061138 morphogenesis of a branching epithelium; GO:0003382 epithelial cell morphogenesis; GO:0008219 cell death; GO:0044767 single-organism developmental process; GO:0060670 branching involved in labyrinthine layer morphogenesis; GO:0060706 cell differentiation involved in embryonic placenta development; GO:0012501 programmed cell death; GO:0071840 cellular component organization or biogenesis; ","GO:0016323 basolateral plasma membrane; GO:0016020 membrane; GO:0031226 intrinsic component of plasma membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0019898 extrinsic component of membrane; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0019897 extrinsic component of plasma membrane; GO:0031224 intrinsic component of membrane; GO:0005887 integral component of plasma membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005886 plasma membrane; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044459 plasma membrane part; GO:0098590 plasma membrane region; GO:0044464 cell part; GO:0044425 membrane part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0004252 serine-type endopeptidase activity; GO:0004175 endopeptidase activity; GO:0008233 peptidase activity; GO:0017171 serine hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0008236 serine-type peptidase activity; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0016787 hydrolase activity; GO:0005515 protein binding; ","K08670","ST14; suppressor of tumorigenicity protein 14 [EC:3.4.21.109]","hsa05206 MicroRNAs in cancer - Homo sapiens (human); ","IPR009003; IPR000859; IPR001254; IPR000082; ","\"Peptidase S1, PA clan; CUB domain; Serine proteases, trypsin domain; SEA domain; \"\r"]
["Q9Y5Z4","Heme-binding protein 2 OS=Homo sapiens OX=9606 GN=HEBP2","HEBP2",22.875,42.142,36.6,7,13,7,1.022,1.084,1.01,0.969,0.953,0.964,0.926,0.0273,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0065008 regulation of biological quality; GO:0010941 regulation of cell death; GO:0045321 leukocyte activation; GO:0002283 neutrophil activation involved in immune response; GO:0007006 mitochondrial membrane organization; GO:0002252 immune effector process; GO:0006839 mitochondrial transport; GO:0044699 single-organism process; GO:0010917 negative regulation of mitochondrial membrane potential; GO:0050896 response to stimulus; GO:0051234 establishment of localization; GO:0046902 regulation of mitochondrial membrane permeability; GO:0002275 myeloid cell activation involved in immune response; GO:1902578 single-organism localization; GO:0010940 positive regulation of necrotic cell death; GO:0007005 mitochondrion organization; GO:0090559 regulation of membrane permeability; GO:0036230 granulocyte activation; GO:0009987 cellular process; GO:0035794 positive regulation of mitochondrial membrane permeability; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0010939 regulation of necrotic cell death; GO:0002443 leukocyte mediated immunity; GO:0016192 vesicle-mediated transport; GO:0002446 neutrophil mediated immunity; GO:0044763 single-organism cellular process; GO:0044802 single-organism membrane organization; GO:0048522 positive regulation of cellular process; GO:0002376 immune system process; GO:0043312 neutrophil degranulation; GO:0002263 cell activation involved in immune response; GO:0048518 positive regulation of biological process; GO:1905710 positive regulation of membrane permeability; GO:0002444 myeloid leukocyte mediated immunity; GO:0010942 positive regulation of cell death; GO:0042391 regulation of membrane potential; GO:0006810 transport; GO:0002366 leukocyte activation involved in immune response; GO:1902589 single-organism organelle organization; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:0050789 regulation of biological process; GO:0006996 organelle organization; GO:0032940 secretion by cell; GO:0061024 membrane organization; GO:0045837 negative regulation of membrane potential; GO:0001775 cell activation; GO:0043299 leukocyte degranulation; GO:0051179 localization; GO:0006955 immune response; GO:0051881 regulation of mitochondrial membrane potential; GO:0071840 cellular component organization or biogenesis; GO:0006887 exocytosis; GO:0065007 biological regulation; ","GO:0034774 secretory granule lumen; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0035578 azurophil granule lumen; GO:0005623 cell; GO:0044422 organelle part; GO:0005775 vacuolar lumen; GO:0031974 membrane-enclosed lumen; GO:0070062 extracellular exosome; GO:0031983 vesicle lumen; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0099503 secretory vesicle; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0000323 lytic vacuole; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0042582 azurophil granule; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0060205 cytoplasmic vesicle lumen; GO:0005766 primary lysosome; GO:0044437 vacuolar part; GO:0005773 vacuole; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR011256; ","\"Regulatory factor, effector binding domain; \"\r"]
["Q9Y606","tRNA pseudouridine synthase A OS=Homo sapiens OX=9606 GN=PUS1","PUS1",47.47,5.4581,4.4,2,2,2,0.951,0.946,0.918,1.068,1.07,1.049,1.132,0.000605,"mitochondria\r","GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0044237 cellular metabolic process; GO:0009451 RNA modification; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0070900 mitochondrial tRNA modification; GO:0006139 nucleobase-containing compound metabolic process; GO:0070525 tRNA threonylcarbamoyladenosine metabolic process; GO:0090646 mitochondrial tRNA processing; GO:0007005 mitochondrion organization; GO:0031119 tRNA pseudouridine synthesis; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0006400 tRNA modification; GO:0009987 cellular process; GO:0000963 mitochondrial RNA processing; GO:0000959 mitochondrial RNA metabolic process; GO:0034470 ncRNA processing; GO:0006396 RNA processing; GO:0016556 mRNA modification; GO:0001522 pseudouridine synthesis; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0070902 mitochondrial tRNA pseudouridine synthesis; GO:0044238 primary metabolic process; GO:0016070 RNA metabolic process; GO:0006399 tRNA metabolic process; GO:0090304 nucleic acid metabolic process; GO:0006996 organelle organization; GO:1990481 mRNA pseudouridine synthesis; GO:0008033 tRNA processing; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:1900864 mitochondrial RNA modification; GO:0043412 macromolecule modification; GO:0016071 mRNA metabolic process; GO:0034660 ncRNA metabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0016853 isomerase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0004730 pseudouridylate synthase activity; GO:0003676 nucleic acid binding; GO:0016829 lyase activity; GO:0016836 hydro-lyase activity; GO:0016866 intramolecular transferase activity; GO:0009982 pseudouridine synthase activity; GO:0016835 carbon-oxygen lyase activity; ","K06173",null,null,"IPR020103; IPR020094; IPR020097; IPR020095; ","\"Pseudouridine synthase, catalytic domain; Pseudouridine synthase I, TruA, N-terminal; Pseudouridine synthase I, TruA, alpha/beta domain; Pseudouridine synthase I, TruA, C-terminal; \"\r"]
["Q9Y613","FH1/FH2 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=FHOD1","FHOD1",126.55,13.36,4,4,4,4,0.898,0.869,1.008,1.057,1.147,1.017,1.161,0.0591,"nucleus\r","GO:0009891 positive regulation of biosynthetic process; GO:0051647 nucleus localization; GO:0040023 establishment of nucleus localization; GO:0051234 establishment of localization; GO:0007097 nuclear migration; GO:0051130 positive regulation of cellular component organization; GO:2001141 regulation of RNA biosynthetic process; GO:0051649 establishment of localization in cell; GO:0051660 establishment of centrosome localization; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0051493 regulation of cytoskeleton organization; GO:0010468 regulation of gene expression; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0061842 microtubule organizing center localization; GO:0045893 positive regulation of transcription, DNA-templated; GO:0048522 positive regulation of cellular process; GO:0031323 regulation of cellular metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0010638 positive regulation of organelle organization; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:1902905 positive regulation of supramolecular fiber organization; GO:0032233 positive regulation of actin filament bundle assembly; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:1902903 regulation of supramolecular fiber organization; GO:0051640 organelle localization; GO:0050794 regulation of cellular process; GO:0032956 regulation of actin cytoskeleton organization; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0044087 regulation of cellular component biogenesis; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0051254 positive regulation of RNA metabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0051495 positive regulation of cytoskeleton organization; GO:0032231 regulation of actin filament bundle assembly; GO:0033043 regulation of organelle organization; GO:0051642 centrosome localization; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0032970 regulation of actin filament-based process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0051656 establishment of organelle localization; GO:0048518 positive regulation of biological process; GO:0051252 regulation of RNA metabolic process; GO:0051492 regulation of stress fiber assembly; GO:0051641 cellular localization; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0031325 positive regulation of cellular metabolic process; GO:0051496 positive regulation of stress fiber assembly; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0031328 positive regulation of cellular biosynthetic process; GO:0044089 positive regulation of cellular component biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0030054 cell junction; GO:0044291 cell-cell contact zone; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0032059 bleb; GO:0005911 cell-cell junction; GO:0005623 cell; GO:0005829 cytosol; GO:0014704 intercalated disc; GO:0043228 non-membrane-bounded organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0043226 organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0003779 actin binding; GO:0005515 protein binding; GO:0008092 cytoskeletal protein binding; GO:0042802 identical protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR014768; IPR011989; IPR015425; IPR016024; ","\"Rho GTPase-binding/formin homology 3 (GBD/FH3) domain; Armadillo-like helical; Formin, FH2 domain; Armadillo-type fold; \"\r"]
["Q9Y617","Phosphoserine aminotransferase OS=Homo sapiens OX=9606 GN=PSAT1","PSAT1",40.422,100.35,31.9,12,16,12,0.901,0.957,0.912,1.124,1.068,1.073,1.179,0.0026,"cytoplasm\r","GO:0009110 vitamin biosynthetic process; GO:0006725 cellular aromatic compound metabolic process; GO:1901615 organic hydroxy compound metabolic process; GO:0016053 organic acid biosynthetic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0006564 L-serine biosynthetic process; GO:0072524 pyridine-containing compound metabolic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0072525 pyridine-containing compound biosynthetic process; GO:0006766 vitamin metabolic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:0046483 heterocycle metabolic process; GO:0008614 pyridoxine metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:1901607 alpha-amino acid biosynthetic process; GO:0042364 water-soluble vitamin biosynthetic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009987 cellular process; GO:0009070 serine family amino acid biosynthetic process; GO:0006767 water-soluble vitamin metabolic process; GO:0042816 vitamin B6 metabolic process; GO:0008652 cellular amino acid biosynthetic process; GO:0018130 heterocycle biosynthetic process; GO:0008615 pyridoxine biosynthetic process; GO:0044711 single-organism biosynthetic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0042819 vitamin B6 biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:1901617 organic hydroxy compound biosynthetic process; GO:1901605 alpha-amino acid metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0046394 carboxylic acid biosynthetic process; GO:0009069 serine family amino acid metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0044710 single-organism metabolic process; GO:0006563 L-serine metabolic process; GO:0044283 small molecule biosynthetic process; GO:0019752 carboxylic acid metabolic process; GO:0006082 organic acid metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0043436 oxoacid metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0016769 transferase activity, transferring nitrogenous groups; GO:0004648 O-phospho-L-serine:2-oxoglutarate aminotransferase activity; GO:0008483 transaminase activity; GO:0003824 catalytic activity; GO:0016740 transferase activity; ","K00831","serC; phosphoserine aminotransferase [EC:2.6.1.52]","hsa00750 Vitamin B6 metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa00260 Glycine, serine and threonine metabolism - Homo sapiens (human); hsa01230 Biosynthesis of amino acids - Homo sapiens (human); hsa01200 Carbon metabolism - Homo sapiens (human); ","IPR015424; IPR000192; IPR015421; IPR015422; ","\"Pyridoxal phosphate-dependent transferase; Aminotransferase class V domain; Pyridoxal phosphate-dependent transferase, major region, subdomain 1; Pyridoxal phosphate-dependent transferase, major region, subdomain 2; \"\r"]
["Q9Y623","Myosin-4 OS=Homo sapiens OX=9606 GN=MYH4","MYH4",223.07,31.614,4.1,8,11,1,0.271,0.284,1.318,1.365,1.284,1.304,2.111,0.184,"cytoplasm\r","GO:0030048 actin filament-based movement; GO:0030049 muscle filament sliding; GO:0070252 actin-mediated cell contraction; GO:0003012 muscle system process; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0009259 ribonucleotide metabolic process; GO:0009117 nucleotide metabolic process; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0071704 organic substance metabolic process; GO:0008152 metabolic process; GO:0006936 muscle contraction; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0009987 cellular process; GO:0009119 ribonucleoside metabolic process; GO:0046034 ATP metabolic process; GO:0003008 system process; GO:0033275 actin-myosin filament sliding; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0006807 nitrogen compound metabolic process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:0032501 multicellular organismal process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0006163 purine nucleotide metabolic process; GO:0046128 purine ribonucleoside metabolic process; GO:0014823 response to activity; GO:0006793 phosphorus metabolic process; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0044710 single-organism metabolic process; GO:0030029 actin filament-based process; GO:0006928 movement of cell or subcellular component; GO:0019637 organophosphate metabolic process; GO:0009126 purine nucleoside monophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0043229 intracellular organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0030016 myofibril; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0005859 muscle myosin complex; GO:0099512 supramolecular fiber; GO:0044424 intracellular part; GO:0099080 supramolecular complex; GO:0005623 cell; GO:0015629 actin cytoskeleton; GO:0044422 organelle part; GO:0099081 supramolecular polymer; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0043226 organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0030017 sarcomere; GO:0016460 myosin II complex; GO:0043292 contractile fiber; GO:0044449 contractile fiber part; GO:0043234 protein complex; GO:0016459 myosin complex; GO:0032982 myosin filament; GO:0044444 cytoplasmic part; ","GO:0003774 motor activity; GO:1901265 nucleoside phosphate binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0016887 ATPase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0008092 cytoskeletal protein binding; GO:0016462 pyrophosphatase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0000146 microfilament motor activity; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003723 RNA binding; GO:0005524 ATP binding; GO:0003725 double-stranded RNA binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0005516 calmodulin binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003676 nucleic acid binding; GO:0003779 actin binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; ","K10352","MYH; myosin heavy chain","hsa05132 Salmonella infection - Homo sapiens (human); hsa04530 Tight junction - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa04270 Vascular smooth muscle contraction - Homo sapiens (human); ","IPR002928; IPR004009; IPR027417; IPR001609; IPR027401; ","\"Myosin tail; Myosin, N-terminal, SH3-like; P-loop containing nucleoside triphosphate hydrolase; Myosin head, motor domain; Myosin-like IQ motif-containing domain; \"\r"]
["Q9Y624","Junctional adhesion molecule A OS=Homo sapiens OX=9606 GN=F11R","F11R",32.583,8.3511,11.7,4,6,4,0.997,0.977,1.115,1.065,0.903,0.956,0.947,0.431,"extracellular\r","GO:0044700 single organism signaling; GO:0044409 entry into host; GO:0044085 cellular component biogenesis; GO:0045777 positive regulation of blood pressure; GO:0065008 regulation of biological quality; GO:0007586 digestion; GO:0007166 cell surface receptor signaling pathway; GO:0090002 establishment of protein localization to plasma membrane; GO:0022610 biological adhesion; GO:0030036 actin cytoskeleton organization; GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0044093 positive regulation of molecular function; GO:0009719 response to endogenous stimulus; GO:0007155 cell adhesion; GO:0070848 response to growth factor; GO:0090559 regulation of membrane permeability; GO:0051493 regulation of cytoskeleton organization; GO:0044419 interspecies interaction between organisms; GO:0008104 protein localization; GO:0046718 viral entry into host cell; GO:0051716 cellular response to stimulus; GO:0002064 epithelial cell development; GO:0072657 protein localization to membrane; GO:0044763 single-organism cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0048870 cell motility; GO:0007009 plasma membrane organization; GO:0071559 response to transforming growth factor beta; GO:0043086 negative regulation of catalytic activity; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0050900 leukocyte migration; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0003013 circulatory system process; GO:0030855 epithelial cell differentiation; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0009628 response to abiotic stimulus; GO:0032956 regulation of actin cytoskeleton organization; GO:0051806 entry into cell of other organism involved in symbiotic interaction; GO:0048519 negative regulation of biological process; GO:0051239 regulation of multicellular organismal process; GO:1990778 protein localization to cell periphery; GO:1902578 single-organism localization; GO:0051345 positive regulation of hydrolase activity; GO:0043062 extracellular structure organization; GO:1902580 single-organism cellular localization; GO:0007010 cytoskeleton organization; GO:0034613 cellular protein localization; GO:0090150 establishment of protein localization to membrane; GO:0043297 apical junction assembly; GO:0006950 response to stress; GO:0043547 positive regulation of GTPase activity; GO:0007179 transforming growth factor beta receptor signaling pathway; GO:0002376 immune system process; GO:0032970 regulation of actin filament-based process; GO:0010033 response to organic substance; GO:0003158 endothelium development; GO:0045184 establishment of protein localization; GO:0090557 establishment of endothelial intestinal barrier; GO:0072659 protein localization to plasma membrane; GO:0001885 endothelial cell development; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0061024 membrane organization; GO:0006928 movement of cell or subcellular component; GO:0051179 localization; GO:0010256 endomembrane system organization; GO:0051674 localization of cell; GO:0050892 intestinal absorption; GO:0048869 cellular developmental process; GO:0045216 cell-cell junction organization; GO:0071560 cellular response to transforming growth factor beta stimulus; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0071363 cellular response to growth factor stimulus; GO:0045446 endothelial cell differentiation; GO:0051234 establishment of localization; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0009314 response to radiation; GO:0030198 extracellular matrix organization; GO:0033036 macromolecule localization; GO:0034260 negative regulation of GTPase activity; GO:0070887 cellular response to chemical stimulus; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0032502 developmental process; GO:0031032 actomyosin structure organization; GO:0060429 epithelium development; GO:0009888 tissue development; GO:0023052 signaling; GO:1902589 single-organism organelle organization; GO:0030260 entry into host cell; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0006954 inflammatory response; GO:0051828 entry into other organism involved in symbiotic interaction; GO:0065009 regulation of molecular function; GO:0043087 regulation of GTPase activity; GO:0044092 negative regulation of molecular function; GO:0006952 defense response; GO:0040011 locomotion; GO:0048856 anatomical structure development; GO:0008217 regulation of blood pressure; GO:0034329 cell junction assembly; GO:0016043 cellular component organization; GO:0016477 cell migration; GO:0019058 viral life cycle; GO:0071310 cellular response to organic substance; GO:0050896 response to stimulus; GO:0051346 negative regulation of hydrolase activity; GO:0048468 cell development; GO:0030154 cell differentiation; GO:0016032 viral process; GO:2000249 regulation of actin cytoskeleton reorganization; GO:0008015 blood circulation; GO:0070830 bicellular tight junction assembly; GO:0009987 cellular process; GO:0061028 establishment of endothelial barrier; GO:0007043 cell-cell junction assembly; GO:0003008 system process; GO:0033043 regulation of organelle organization; GO:0044802 single-organism membrane organization; GO:0051701 interaction with host; GO:0051641 cellular localization; GO:0043085 positive regulation of catalytic activity; GO:0070727 cellular macromolecule localization; GO:0034330 cell junction organization; GO:0044767 single-organism developmental process; GO:0071495 cellular response to endogenous stimulus; GO:0022600 digestive system process; GO:0001817 regulation of cytokine production; GO:0051128 regulation of cellular component organization; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0036057 slit diaphragm; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005911 cell-cell junction; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0005923 bicellular tight junction; GO:0005576 extracellular region; GO:0043296 apical junction complex; GO:0005886 plasma membrane; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0070160 occluding junction; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0036056 filtration diaphragm; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0050839 cell adhesion molecule binding; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0005488 binding; GO:0045296 cadherin binding; GO:0005515 protein binding; GO:0019904 protein domain specific binding; GO:0030165 PDZ domain binding; GO:0001618 virus receptor activity; ","K06089","F11R; junctional adhesion molecule 1","hsa05120 Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human); hsa04670 Leukocyte transendothelial migration - Homo sapiens (human); hsa04530 Tight junction - Homo sapiens (human); hsa04514 Cell adhesion molecules (CAMs) - Homo sapiens (human); ","IPR003598; IPR007110; IPR013783; IPR013106; IPR003599; IPR013151; ","Immunoglobulin subtype 2; Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin V-set domain; Immunoglobulin subtype; Immunoglobulin; \r"]
["Q9Y639","Neuroplastin OS=Homo sapiens OX=9606 GN=NPTN","NPTN",44.387,14.312,12.8,4,4,4,1.098,0.979,0.94,0.959,0.986,1.047,0.992,0.904,"extracellular\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:1900271 regulation of long-term synaptic potentiation; GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0007166 cell surface receptor signaling pathway; GO:0018212 peptidyl-tyrosine modification; GO:0044237 cellular metabolic process; GO:0050877 neurological system process; GO:0007610 behavior; GO:0022610 biological adhesion; GO:0008152 metabolic process; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:1902683 regulation of receptor localization to synapse; GO:0055065 metal ion homeostasis; GO:0048170 positive regulation of long-term neuronal synaptic plasticity; GO:0007155 cell adhesion; GO:0042327 positive regulation of phosphorylation; GO:0010562 positive regulation of phosphorus metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0007399 nervous system development; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0051174 regulation of phosphorus metabolic process; GO:0080090 regulation of primary metabolic process; GO:0031346 positive regulation of cell projection organization; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0090287 regulation of cellular response to growth factor stimulus; GO:0060291 long-term synaptic potentiation; GO:0048168 regulation of neuronal synaptic plasticity; GO:0031323 regulation of cellular metabolic process; GO:0032501 multicellular organismal process; GO:0006874 cellular calcium ion homeostasis; GO:0007612 learning; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0051094 positive regulation of developmental process; GO:0048169 regulation of long-term neuronal synaptic plasticity; GO:0010975 regulation of neuron projection development; GO:0044708 single-organism behavior; GO:0050794 regulation of cellular process; GO:0016310 phosphorylation; GO:0044707 single-multicellular organism process; GO:0009628 response to abiotic stimulus; GO:0031399 regulation of protein modification process; GO:0044267 cellular protein metabolic process; GO:0051239 regulation of multicellular organismal process; GO:0045597 positive regulation of cell differentiation; GO:0060341 regulation of cellular localization; GO:0070372 regulation of ERK1 and ERK2 cascade; GO:0032880 regulation of protein localization; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:1904861 excitatory synapse assembly; GO:0048878 chemical homeostasis; GO:0040036 regulation of fibroblast growth factor receptor signaling pathway; GO:0048167 regulation of synaptic plasticity; GO:0008542 visual learning; GO:1902531 regulation of intracellular signal transduction; GO:0009416 response to light stimulus; GO:0048731 system development; GO:0050804 modulation of synaptic transmission; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0007416 synapse assembly; GO:0044238 primary metabolic process; GO:0050808 synapse organization; GO:0051247 positive regulation of protein metabolic process; GO:0006873 cellular ion homeostasis; GO:0010976 positive regulation of neuron projection development; GO:0006793 phosphorus metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0050769 positive regulation of neurogenesis; GO:0007204 positive regulation of cytosolic calcium ion concentration; GO:0048584 positive regulation of response to stimulus; GO:0043412 macromolecule modification; GO:0050793 regulation of developmental process; GO:1903827 regulation of cellular protein localization; GO:0045666 positive regulation of neuron differentiation; GO:0072503 cellular divalent inorganic cation homeostasis; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0006796 phosphate-containing compound metabolic process; GO:0051130 positive regulation of cellular component organization; GO:0007165 signal transduction; GO:0050806 positive regulation of synaptic transmission; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0022607 cellular component assembly; GO:0009893 positive regulation of metabolic process; GO:0009314 response to radiation; GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules; GO:0010720 positive regulation of cell development; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0032502 developmental process; GO:0045937 positive regulation of phosphate metabolic process; GO:0050801 ion homeostasis; GO:0007632 visual behavior; GO:0055074 calcium ion homeostasis; GO:0098771 inorganic ion homeostasis; GO:0051962 positive regulation of nervous system development; GO:0098609 cell-cell adhesion; GO:0019725 cellular homeostasis; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0018108 peptidyl-tyrosine phosphorylation; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0045664 regulation of neuron differentiation; GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway; GO:0019222 regulation of metabolic process; GO:0019220 regulation of phosphate metabolic process; GO:0036211 protein modification process; GO:0072507 divalent inorganic cation homeostasis; GO:0048856 anatomical structure development; GO:2000026 regulation of multicellular organismal development; GO:0016043 cellular component organization; GO:1903829 positive regulation of cellular protein localization; GO:0060255 regulation of macromolecule metabolic process; GO:0030003 cellular cation homeostasis; GO:0051480 regulation of cytosolic calcium ion concentration; GO:0031344 regulation of cell projection organization; GO:0050896 response to stimulus; GO:0055082 cellular chemical homeostasis; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:0006468 protein phosphorylation; GO:0043408 regulation of MAPK cascade; GO:0055080 cation homeostasis; GO:0023056 positive regulation of signaling; GO:0050890 cognition; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0003008 system process; GO:0001932 regulation of protein phosphorylation; GO:0031401 positive regulation of protein modification process; GO:0001934 positive regulation of protein phosphorylation; GO:0048518 positive regulation of biological process; GO:0007611 learning or memory; GO:0018193 peptidyl-amino acid modification; GO:1900273 positive regulation of long-term synaptic potentiation; GO:0044767 single-organism developmental process; GO:0051246 regulation of protein metabolic process; GO:0006875 cellular metal ion homeostasis; GO:0009967 positive regulation of signal transduction; GO:0051128 regulation of cellular component organization; GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules; GO:0008306 associative learning; GO:0043410 positive regulation of MAPK cascade; GO:0070374 positive regulation of ERK1 and ERK2 cascade; GO:0071840 cellular component organization or biogenesis; GO:0050767 regulation of neurogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0030425 dendrite; GO:0042995 cell projection; GO:0071944 cell periphery; GO:0031224 intrinsic component of membrane; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0042734 presynaptic membrane; GO:0032279 asymmetric synapse; GO:0045202 synapse; GO:0005886 plasma membrane; GO:0043226 organelle; GO:0036477 somatodendritic compartment; GO:0098794 postsynapse; GO:0044459 plasma membrane part; GO:0098590 plasma membrane region; GO:0044464 cell part; GO:0098793 presynapse; GO:0044425 membrane part; GO:0014069 postsynaptic density; GO:0043005 neuron projection; GO:0097060 synaptic membrane; GO:0009986 cell surface; GO:0060077 inhibitory synapse; GO:0099572 postsynaptic specialization; GO:0097458 neuron part; GO:0098984 neuron to neuron synapse; GO:0044456 synapse part; ","GO:0038023 signaling receptor activity; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0005102 receptor binding; GO:0004713 protein tyrosine kinase activity; GO:0070851 growth factor receptor binding; GO:0005515 protein binding; GO:0004672 protein kinase activity; GO:0004888 transmembrane signaling receptor activity; GO:0005105 type 1 fibroblast growth factor receptor binding; GO:0004871 signal transducer activity; GO:0004714 transmembrane receptor protein tyrosine kinase activity; GO:0005104 fibroblast growth factor receptor binding; GO:0050839 cell adhesion molecule binding; GO:0019199 transmembrane receptor protein kinase activity; GO:0060089 molecular transducer activity; GO:0016301 kinase activity; GO:0004872 receptor activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0044325 ion channel binding; GO:0016740 transferase activity; GO:0099600 transmembrane receptor activity; GO:0016772 transferase activity, transferring phosphorus-containing groups; ",{"$nulls":3},"IPR003598; IPR007110; IPR013783; IPR003599; ","Immunoglobulin subtype 2; Immunoglobulin-like domain; Immunoglobulin-like fold; Immunoglobulin subtype; \r"]
["Q9Y646","Carboxypeptidase Q OS=Homo sapiens OX=9606 GN=CPQ","CPQ",51.887,46.495,14.4,7,9,7,1.285,1.17,1.187,0.8,0.81,0.778,0.656,0.00018,"plasma membrane\r","GO:0065008 regulation of biological quality; GO:0006518 peptide metabolic process; GO:0006725 cellular aromatic compound metabolic process; GO:1901615 organic hydroxy compound metabolic process; GO:0044699 single-organism process; GO:0050896 response to stimulus; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0009611 response to wounding; GO:0008152 metabolic process; GO:0006575 cellular modified amino acid metabolic process; GO:0043171 peptide catabolic process; GO:0044248 cellular catabolic process; GO:0006508 proteolysis; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0009987 cellular process; GO:0032502 developmental process; GO:0042445 hormone metabolic process; GO:0009888 tissue development; GO:0006950 response to stress; GO:0042246 tissue regeneration; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0043603 cellular amide metabolic process; GO:0044238 primary metabolic process; GO:1901575 organic substance catabolic process; GO:1901565 organonitrogen compound catabolic process; GO:0042060 wound healing; GO:0018958 phenol-containing compound metabolic process; GO:0044767 single-organism developmental process; GO:0010817 regulation of hormone levels; GO:0006590 thyroid hormone generation; GO:0031099 regeneration; GO:0048589 developmental growth; GO:0040007 growth; GO:0048856 anatomical structure development; GO:0009056 catabolic process; GO:0065007 biological regulation; GO:0042403 thyroid hormone metabolic process; GO:1901564 organonitrogen compound metabolic process; ","GO:0043229 intracellular organelle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0005783 endoplasmic reticulum; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0005576 extracellular region; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:0005764 lysosome; GO:1903561 extracellular vesicle; GO:0005773 vacuole; GO:0005794 Golgi apparatus; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0000323 lytic vacuole; ","GO:0004180 carboxypeptidase activity; GO:0008233 peptidase activity; GO:0008238 exopeptidase activity; GO:0043167 ion binding; GO:0008235 metalloexopeptidase activity; GO:0046983 protein dimerization activity; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0008237 metallopeptidase activity; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0042803 protein homodimerization activity; GO:0070573 metallodipeptidase activity; GO:0046872 metal ion binding; GO:0070011 peptidase activity, acting on L-amino acid peptides; GO:0043169 cation binding; GO:0016805 dipeptidase activity; ","K01302",null,null,"IPR007484; ","Peptidase M28; \r"]
["Q9Y653","Adhesion G-protein coupled receptor G1 OS=Homo sapiens OX=9606 GN=ADGRG1","ADGRG1",77.737,3.6697,1.4,1,2,1,0.962,1.18,0.873,0.907,1.003,1.086,0.994,0.993,"plasma membrane\r","GO:0044700 single organism signaling; GO:0022414 reproductive process; GO:0007166 cell surface receptor signaling pathway; GO:0007420 brain development; GO:0008584 male gonad development; GO:0010573 vascular endothelial growth factor production; GO:0021987 cerebral cortex development; GO:0008285 negative regulation of cell proliferation; GO:0021537 telencephalon development; GO:0022610 biological adhesion; GO:0001525 angiogenesis; GO:0021796 cerebral cortex regionalization; GO:0032879 regulation of localization; GO:0044702 single organism reproductive process; GO:0021885 forebrain cell migration; GO:0007155 cell adhesion; GO:0051056 regulation of small GTPase mediated signal transduction; GO:0007399 nervous system development; GO:0051716 cellular response to stimulus; GO:0003006 developmental process involved in reproduction; GO:0048699 generation of neurons; GO:0044763 single-organism cellular process; GO:0008347 glial cell migration; GO:0007264 small GTPase mediated signal transduction; GO:0048870 cell motility; GO:2000146 negative regulation of cell motility; GO:0032501 multicellular organismal process; GO:0050768 negative regulation of neurogenesis; GO:0022029 telencephalon cell migration; GO:0048513 animal organ development; GO:0042063 gliogenesis; GO:0007267 cell-cell signaling; GO:0007417 central nervous system development; GO:0048583 regulation of response to stimulus; GO:2000179 positive regulation of neural precursor cell proliferation; GO:0010721 negative regulation of cell development; GO:0000003 reproduction; GO:0050794 regulation of cellular process; GO:0072359 circulatory system development; GO:0044707 single-multicellular organism process; GO:0042127 regulation of cell proliferation; GO:0008406 gonad development; GO:0007389 pattern specification process; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0051239 regulation of multicellular organismal process; GO:0009653 anatomical structure morphogenesis; GO:2000145 regulation of cell motility; GO:0007548 sex differentiation; GO:0030900 forebrain development; GO:0007275 multicellular organism development; GO:0061458 reproductive system development; GO:0009966 regulation of signal transduction; GO:0048646 anatomical structure formation involved in morphogenesis; GO:1902531 regulation of intracellular signal transduction; GO:0045785 positive regulation of cell adhesion; GO:0051270 regulation of cellular component movement; GO:0021801 cerebral cortex radial glia guided migration; GO:0051057 positive regulation of small GTPase mediated signal transduction; GO:0048731 system development; GO:0051960 regulation of nervous system development; GO:0060284 regulation of cell development; GO:0030334 regulation of cell migration; GO:0072358 cardiovascular system development; GO:0030155 regulation of cell adhesion; GO:0007186 G-protein coupled receptor signaling pathway; GO:0030336 negative regulation of cell migration; GO:0001816 cytokine production; GO:0006928 movement of cell or subcellular component; GO:2001222 regulation of neuron migration; GO:0046546 development of primary male sexual characteristics; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0035023 regulation of Rho protein signal transduction; GO:0008284 positive regulation of cell proliferation; GO:0051093 negative regulation of developmental process; GO:0051674 localization of cell; GO:0001568 blood vessel development; GO:0048869 cellular developmental process; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0022008 neurogenesis; GO:0051241 negative regulation of multicellular organismal process; GO:0040013 negative regulation of locomotion; GO:0007165 signal transduction; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0007266 Rho protein signal transduction; GO:0060322 head development; GO:0048514 blood vessel morphogenesis; GO:0045596 negative regulation of cell differentiation; GO:0032502 developmental process; GO:0035295 tube development; GO:0021978 telencephalon regionalization; GO:0048608 reproductive structure development; GO:0001944 vasculature development; GO:0048522 positive regulation of cellular process; GO:0046579 positive regulation of Ras protein signal transduction; GO:0023052 signaling; GO:0050789 regulation of biological process; GO:0021871 forebrain regionalization; GO:0040011 locomotion; GO:0072520 seminiferous tubule development; GO:0048856 anatomical structure development; GO:0007265 Ras protein signal transduction; GO:0051271 negative regulation of cellular component movement; GO:2000026 regulation of multicellular organismal development; GO:0021543 pallium development; GO:0016477 cell migration; GO:0021799 cerebral cortex radially oriented cell migration; GO:0046661 male sex differentiation; GO:0021795 cerebral cortex cell migration; GO:0046578 regulation of Ras protein signal transduction; GO:0050896 response to stimulus; GO:0030154 cell differentiation; GO:0070528 protein kinase C signaling; GO:0051961 negative regulation of nervous system development; GO:0023056 positive regulation of signaling; GO:0035025 positive regulation of Rho protein signal transduction; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:0045137 development of primary sexual characteristics; GO:0045595 regulation of cell differentiation; GO:0003002 regionalization; GO:0035556 intracellular signal transduction; GO:0021819 layer formation in cerebral cortex; GO:0048518 positive regulation of biological process; GO:2000177 regulation of neural precursor cell proliferation; GO:0044767 single-organism developmental process; GO:2001223 negative regulation of neuron migration; GO:0009967 positive regulation of signal transduction; GO:0040012 regulation of locomotion; GO:0022030 telencephalon glial cell migration; GO:0065007 biological regulation; GO:0050767 regulation of neurogenesis; ","GO:0016020 membrane; GO:0042995 cell projection; GO:0044421 extracellular region part; GO:0031226 intrinsic component of plasma membrane; GO:0098857 membrane microdomain; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0031224 intrinsic component of membrane; GO:0005887 integral component of plasma membrane; GO:0097451 glial limiting end-foot; GO:0005623 cell; GO:0005576 extracellular region; GO:0016021 integral component of membrane; GO:0097386 glial cell projection; GO:0097449 astrocyte projection; GO:0005886 plasma membrane; GO:0097450 astrocyte end-foot; GO:0043226 organelle; GO:0070062 extracellular exosome; GO:0044459 plasma membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0098589 membrane region; GO:1903561 extracellular vesicle; GO:0045121 membrane raft; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; ","GO:0038023 signaling receptor activity; GO:0004930 G-protein coupled receptor activity; GO:0044877 macromolecular complex binding; GO:0043167 ion binding; GO:0005515 protein binding; GO:0004888 transmembrane signaling receptor activity; GO:0008201 heparin binding; GO:0004871 signal transducer activity; GO:1901681 sulfur compound binding; GO:0050840 extracellular matrix binding; GO:0097367 carbohydrate derivative binding; GO:0060089 molecular transducer activity; GO:0004872 receptor activity; GO:0005488 binding; GO:0005518 collagen binding; GO:0043168 anion binding; GO:0005539 glycosaminoglycan binding; GO:0032403 protein complex binding; GO:0099600 transmembrane receptor activity; ","K08450",null,null,"IPR017981; IPR000203; ","\"GPCR, family 2-like; GPS motif; \"\r"]
["Q9Y678","Coatomer subunit gamma-1 OS=Homo sapiens OX=9606 GN=COPG1","COPG1",97.717,173.78,23.6,17,25,14,1.001,1.05,1.005,0.931,1.032,0.977,0.962,0.305,"cytoplasm\r","GO:0072384 organelle transport along microtubule; GO:0051640 organelle localization; GO:0046907 intracellular transport; GO:0048193 Golgi vesicle transport; GO:0044699 single-organism process; GO:0015031 protein transport; GO:0030705 cytoskeleton-dependent intracellular transport; GO:0099111 microtubule-based transport; GO:0051234 establishment of localization; GO:0010970 transport along microtubule; GO:0051649 establishment of localization in cell; GO:1902578 single-organism localization; GO:0006886 intracellular protein transport; GO:1902580 single-organism cellular localization; GO:0034613 cellular protein localization; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0009987 cellular process; GO:0044765 single-organism transport; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0071702 organic substance transport; GO:0051656 establishment of organelle localization; GO:0007017 microtubule-based process; GO:1902582 single-organism intracellular transport; GO:0051683 establishment of Golgi localization; GO:0051641 cellular localization; GO:0006810 transport; GO:0045184 establishment of protein localization; GO:0007018 microtubule-based movement; GO:0070727 cellular macromolecule localization; GO:0006890 retrograde vesicle-mediated transport, Golgi to ER; GO:0006928 movement of cell or subcellular component; GO:0051645 Golgi localization; GO:0051179 localization; GO:0006888 ER to Golgi vesicle-mediated transport; ","GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0098796 membrane protein complex; GO:0030137 COPI-coated vesicle; GO:0030660 Golgi-associated vesicle membrane; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0030120 vesicle coat; GO:0030663 COPI-coated vesicle membrane; GO:0005623 cell; GO:0030662 coated vesicle membrane; GO:0044422 organelle part; GO:0030126 COPI vesicle coat; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0044431 Golgi apparatus part; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0048475 coated membrane; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0012506 vesicle membrane; GO:0005829 cytosol; GO:0030135 coated vesicle; GO:0005798 Golgi-associated vesicle; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044432 endoplasmic reticulum part; GO:0030117 membrane coat; GO:0030133 transport vesicle; GO:0043234 protein complex; GO:0005794 Golgi apparatus; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0005198 structural molecule activity; GO:0005488 binding; ","K17267",null,null,"IPR013040; IPR011989; IPR002553; IPR032154; IPR016024; IPR009028; IPR015873; IPR013041; ","\"Coatomer, gamma subunit, appendage, Ig-like subdomain; Armadillo-like helical; Clathrin/coatomer adaptor, adaptin-like, N-terminal; Coatomer subunit gamma, C-terminal; Armadillo-type fold; Coatomer/calthrin adaptor appendage, C-terminal subdomain; Clathrin alpha-adaptin/coatomer adaptor, appendage, C-terminal subdomain; Coatomer/clathrin adaptor appendage, Ig-like subdomain; \"\r"]
["Q9Y680","Peptidyl-prolyl cis-trans isomerase FKBP7 OS=Homo sapiens OX=9606 GN=FKBP7","FKBP7",25.794,16.662,27,7,7,7,1.089,1.206,1.116,0.902,0.894,0.869,0.781,0.00168,"extracellular\r","GO:0061077 chaperone-mediated protein folding; GO:0044267 cellular protein metabolic process; GO:0044238 primary metabolic process; GO:0018208 peptidyl-proline modification; GO:0000413 protein peptidyl-prolyl isomerization; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:0006457 protein folding; GO:0018193 peptidyl-amino acid modification; GO:0008152 metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:0019538 protein metabolic process; GO:0043170 macromolecule metabolic process; GO:0043412 macromolecule modification; GO:0036211 protein modification process; GO:0009987 cellular process; ","GO:0005788 endoplasmic reticulum lumen; GO:0043229 intracellular organelle; GO:0005783 endoplasmic reticulum; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0070013 intracellular organelle lumen; GO:0044432 endoplasmic reticulum part; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; ","GO:0003755 peptidyl-prolyl cis-trans isomerase activity; GO:0043167 ion binding; GO:0005515 protein binding; GO:0008144 drug binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0016853 isomerase activity; GO:0003824 catalytic activity; GO:0005488 binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0005509 calcium ion binding; GO:0005527 macrolide binding; GO:0005528 FK506 binding; GO:0016859 cis-trans isomerase activity; ","K09573",null,null,"IPR002048; IPR011992; IPR001179; ","EF-hand domain; EF-hand domain pair; FKBP-type peptidyl-prolyl cis-trans isomerase domain; \r"]
["Q9Y696","Chloride intracellular channel protein 4 OS=Homo sapiens OX=9606 GN=CLIC4","CLIC4",28.772,50.693,31.2,7,12,7,1.084,1.124,1.016,0.902,0.945,0.944,0.866,0.0125,"cytoplasm\r","GO:0065008 regulation of biological quality; GO:0022414 reproductive process; GO:0035088 establishment or maintenance of apical/basal cell polarity; GO:0032989 cellular component morphogenesis; GO:0030641 regulation of cellular pH; GO:0030004 cellular monovalent inorganic cation homeostasis; GO:0048754 branching morphogenesis of an epithelial tube; GO:0009913 epidermal cell differentiation; GO:0001525 angiogenesis; GO:0032879 regulation of localization; GO:0044702 single organism reproductive process; GO:0008544 epidermis development; GO:0051493 regulation of cytoskeleton organization; GO:0051716 cellular response to stimulus; GO:0002064 epithelial cell development; GO:0043588 skin development; GO:0035239 tube morphogenesis; GO:0001763 morphogenesis of a branching structure; GO:0043269 regulation of ion transport; GO:0019953 sexual reproduction; GO:0044763 single-organism cellular process; GO:0007163 establishment or maintenance of cell polarity; GO:2000146 negative regulation of cell motility; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0034762 regulation of transmembrane transport; GO:0000902 cell morphogenesis; GO:0006810 transport; GO:0048513 animal organ development; GO:0015698 inorganic anion transport; GO:0030855 epithelial cell differentiation; GO:0000003 reproduction; GO:0050794 regulation of cellular process; GO:0072359 circulatory system development; GO:0002009 morphogenesis of an epithelium; GO:0044707 single-multicellular organism process; GO:0034220 ion transmembrane transport; GO:0006885 regulation of pH; GO:0007035 vacuolar acidification; GO:0006821 chloride transport; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0009653 anatomical structure morphogenesis; GO:0001654 eye development; GO:2000145 regulation of cell motility; GO:0007275 multicellular organism development; GO:0061245 establishment or maintenance of bipolar cell polarity; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0048878 chemical homeostasis; GO:0060562 epithelial tube morphogenesis; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0030334 regulation of cell migration; GO:0072358 cardiovascular system development; GO:0003158 endothelium development; GO:0055085 transmembrane transport; GO:0003382 epithelial cell morphogenesis; GO:0061138 morphogenesis of a branching epithelium; GO:0030336 negative regulation of cell migration; GO:0006873 cellular ion homeostasis; GO:0051453 regulation of intracellular pH; GO:0001885 endothelial cell development; GO:0006811 ion transport; GO:0071248 cellular response to metal ion; GO:0048589 developmental growth; GO:0007423 sensory organ development; GO:0051179 localization; GO:0040007 growth; GO:0098661 inorganic anion transmembrane transport; GO:0001568 blood vessel development; GO:0048869 cellular developmental process; GO:0044699 single-organism process; GO:0045446 endothelial cell differentiation; GO:0051234 establishment of localization; GO:0040013 negative regulation of locomotion; GO:0048729 tissue morphogenesis; GO:0048514 blood vessel morphogenesis; GO:0010035 response to inorganic substance; GO:0070887 cellular response to chemical stimulus; GO:0032502 developmental process; GO:0060429 epithelium development; GO:0035295 tube development; GO:0009888 tissue development; GO:0030216 keratinocyte differentiation; GO:0050801 ion homeostasis; GO:0098771 inorganic ion homeostasis; GO:0019725 cellular homeostasis; GO:0001944 vasculature development; GO:0010038 response to metal ion; GO:0009566 fertilization; GO:0050789 regulation of biological process; GO:0042221 response to chemical; GO:0071241 cellular response to inorganic substance; GO:0048856 anatomical structure development; GO:0051271 negative regulation of cellular component movement; GO:0016043 cellular component organization; GO:0043010 camera-type eye development; GO:0045851 pH reduction; GO:0030003 cellular cation homeostasis; GO:0050896 response to stimulus; GO:0098656 anion transmembrane transport; GO:0055082 cellular chemical homeostasis; GO:0048468 cell development; GO:1902476 chloride transmembrane transport; GO:0000904 cell morphogenesis involved in differentiation; GO:0042592 homeostatic process; GO:0030154 cell differentiation; GO:0055080 cation homeostasis; GO:0061299 retina vasculature morphogenesis in camera-type eye; GO:0035264 multicellular organism growth; GO:0051592 response to calcium ion; GO:0009987 cellular process; GO:0061298 retina vasculature development in camera-type eye; GO:0060041 retina development in camera-type eye; GO:0055067 monovalent inorganic cation homeostasis; GO:0098660 inorganic ion transmembrane transport; GO:0051049 regulation of transport; GO:0033043 regulation of organelle organization; GO:0071277 cellular response to calcium ion; GO:0006820 anion transport; GO:0001886 endothelial cell morphogenesis; GO:0034765 regulation of ion transmembrane transport; GO:0044767 single-organism developmental process; GO:0044703 multi-organism reproductive process; GO:0051452 intracellular pH reduction; GO:0051128 regulation of cellular component organization; GO:0040012 regulation of locomotion; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0030054 cell junction; GO:0005737 cytoplasm; GO:0031982 vesicle; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0098858 actin-based cell projection; GO:0005911 cell-cell junction; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0005815 microtubule organizing center; GO:0070013 intracellular organelle lumen; GO:0015630 microtubule cytoskeleton; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0048471 perinuclear region of cytoplasm; GO:0034702 ion channel complex; GO:1990351 transporter complex; GO:0043227 membrane-bounded organelle; GO:0045177 apical part of cell; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0030496 midbody; GO:0031981 nuclear lumen; GO:0012506 vesicle membrane; GO:1902495 transmembrane transporter complex; GO:0005829 cytosol; GO:0016021 integral component of membrane; GO:0015629 actin cytoskeleton; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0005886 plasma membrane; GO:0030659 cytoplasmic vesicle membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0005813 centrosome; GO:0016363 nuclear matrix; GO:0034707 chloride channel complex; GO:0005902 microvillus; GO:0009986 cell surface; GO:0034399 nuclear periphery; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0015075 ion transmembrane transporter activity; GO:0022803 passive transmembrane transporter activity; GO:0005253 anion channel activity; GO:0022892 substrate-specific transporter activity; GO:0005515 protein binding; GO:0005254 chloride channel activity; GO:0015267 channel activity; GO:0015103 inorganic anion transmembrane transporter activity; GO:0022891 substrate-specific transmembrane transporter activity; GO:0015108 chloride transmembrane transporter activity; GO:0005244 voltage-gated ion channel activity; GO:0022838 substrate-specific channel activity; GO:0005488 binding; GO:0022836 gated channel activity; GO:0005216 ion channel activity; GO:0022832 voltage-gated channel activity; GO:0008509 anion transmembrane transporter activity; GO:0005215 transporter activity; GO:0022857 transmembrane transporter activity; ","K05024",null,null,"IPR010987; IPR012336; ","\"Glutathione S-transferase, C-terminal-like; Thioredoxin-like fold; \"\r"]
["Q9Y697","Cysteine desulfurase, mitochondrial OS=Homo sapiens OX=9606 GN=NFS1","NFS1",50.195,5.2445,4.8,2,3,2,1.129,0.983,1.086,0.902,0.987,0.926,0.88,0.0616,"mitochondria\r","GO:0018282 metal incorporation into metallo-sulfur cluster; GO:0044085 cellular component biogenesis; GO:0051188 cofactor biosynthetic process; GO:0009116 nucleoside metabolic process; GO:0042278 purine nucleoside metabolic process; GO:0043545 molybdopterin cofactor metabolic process; GO:0032324 molybdopterin cofactor biosynthetic process; GO:0009117 nucleotide metabolic process; GO:0006777 Mo-molybdopterin cofactor biosynthetic process; GO:0044699 single-organism process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0000096 sulfur amino acid metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0008152 metabolic process; GO:0006520 cellular amino acid metabolic process; GO:1901068 guanosine-containing compound metabolic process; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0006753 nucleoside phosphate metabolic process; GO:0019693 ribose phosphate metabolic process; GO:0009108 coenzyme biosynthetic process; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0006790 sulfur compound metabolic process; GO:0018130 heterocycle biosynthetic process; GO:0044571 [2Fe-2S] cluster assembly; GO:0071822 protein complex subunit organization; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0006732 coenzyme metabolic process; GO:0018283 iron incorporation into metallo-sulfur cluster; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0051186 cofactor metabolic process; GO:0090407 organophosphate biosynthetic process; GO:0044710 single-organism metabolic process; GO:0044260 cellular macromolecule metabolic process; GO:0006464 cellular protein modification process; GO:1901657 glycosyl compound metabolic process; GO:0070271 protein complex biogenesis; GO:0006082 organic acid metabolic process; GO:0036211 protein modification process; GO:0043436 oxoacid metabolic process; GO:0046039 GTP metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0009259 ribonucleotide metabolic process; GO:0044267 cellular protein metabolic process; GO:1901566 organonitrogen compound biosynthetic process; GO:0019720 Mo-molybdopterin cofactor metabolic process; GO:0071704 organic substance metabolic process; GO:0031163 metallo-sulfur cluster assembly; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0016226 iron-sulfur cluster assembly; GO:1901135 carbohydrate derivative metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009987 cellular process; GO:0009119 ribonucleoside metabolic process; GO:0006461 protein complex assembly; GO:0044711 single-organism biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0009141 nucleoside triphosphate metabolic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0006163 purine nucleotide metabolic process; GO:0043933 macromolecular complex subunit organization; GO:0046128 purine ribonucleoside metabolic process; GO:0006793 phosphorus metabolic process; GO:0019752 carboxylic acid metabolic process; GO:0051189 prosthetic group metabolic process; GO:0019637 organophosphate metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0043412 macromolecule modification; GO:1901564 organonitrogen compound metabolic process; GO:0071840 cellular component organization or biogenesis; ","GO:0005759 mitochondrial matrix; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0005737 cytoplasm; GO:0044446 intracellular organelle part; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005739 mitochondrion; GO:0044422 organelle part; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0044464 cell part; GO:0005622 intracellular; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:0046983 protein dimerization activity; GO:0043167 ion binding; GO:0031071 cysteine desulfurase activity; GO:0005515 protein binding; GO:0016783 sulfurtransferase activity; GO:0048037 cofactor binding; GO:0030170 pyridoxal phosphate binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0042802 identical protein binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0051536 iron-sulfur cluster binding; GO:0042803 protein homodimerization activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0016782 transferase activity, transferring sulfur-containing groups; GO:0016740 transferase activity; GO:0051540 metal cluster binding; ","K04487","iscS; cysteine desulfurase [EC:2.8.1.7]","hsa00730 Thiamine metabolism - Homo sapiens (human); hsa01100 Metabolic pathways - Homo sapiens (human); hsa04122 Sulfur relay system - Homo sapiens (human); ","IPR015424; IPR000192; IPR015421; IPR015422; ","\"Pyridoxal phosphate-dependent transferase; Aminotransferase class V domain; Pyridoxal phosphate-dependent transferase, major region, subdomain 1; Pyridoxal phosphate-dependent transferase, major region, subdomain 2; \"\r"]
["Q9Y6A9","Signal peptidase complex subunit 1 OS=Homo sapiens OX=9606 GN=SPCS1","SPCS1",11.805,19.869,16.7,1,1,1,0.96,0.845,0.933,1.187,1.087,0.988,1.191,0.057,"plasma membrane\r","GO:0046907 intracellular transport; GO:0072594 establishment of protein localization to organelle; GO:0006518 peptide metabolic process; GO:0006465 signal peptide processing; GO:0044267 cellular protein metabolic process; GO:0016485 protein processing; GO:0044237 cellular metabolic process; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0071704 organic substance metabolic process; GO:0006605 protein targeting; GO:0008152 metabolic process; GO:0051649 establishment of localization in cell; GO:0070972 protein localization to endoplasmic reticulum; GO:0006886 intracellular protein transport; GO:0034641 cellular nitrogen compound metabolic process; GO:0006508 proteolysis; GO:0033365 protein localization to organelle; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0034613 cellular protein localization; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0009987 cellular process; GO:0072599 establishment of protein localization to endoplasmic reticulum; GO:0006807 nitrogen compound metabolic process; GO:0071702 organic substance transport; GO:0045047 protein targeting to ER; GO:0043603 cellular amide metabolic process; GO:0044238 primary metabolic process; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:0070727 cellular macromolecule localization; GO:0044260 cellular macromolecule metabolic process; GO:0010467 gene expression; GO:0051179 localization; GO:0051604 protein maturation; GO:1901564 organonitrogen compound metabolic process; ","GO:0016020 membrane; GO:0043229 intracellular organelle; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0098796 membrane protein complex; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0032991 macromolecular complex; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005623 cell; GO:0016021 integral component of membrane; GO:0044422 organelle part; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:1902494 catalytic complex; GO:0044432 endoplasmic reticulum part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0031227 intrinsic component of endoplasmic reticulum membrane; GO:0005787 signal peptidase complex; GO:1905368 peptidase complex; GO:0030176 integral component of endoplasmic reticulum membrane; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0044444 cytoplasmic part; ","GO:0005515 protein binding; GO:0008233 peptidase activity; GO:0016787 hydrolase activity; GO:0003824 catalytic activity; GO:0005488 binding; ","K12946","SPCS1; signal peptidase complex subunit 1 [EC:3.4.-.-]","hsa03060 Protein export - Homo sapiens (human); "]
["Q9Y6B6","GTP-binding protein SAR1b OS=Homo sapiens OX=9606 GN=SAR1B","SAR1B",22.41,37.8,40.9,7,11,4,0.955,0.955,0.876,1.005,1.158,1.128,1.181,0.0338,"cytoplasm\r","GO:0044085 cellular component biogenesis; GO:0051640 organelle localization; GO:0016043 cellular component organization; GO:0006901 vesicle coating; GO:0046907 intracellular transport; GO:0048207 vesicle targeting, rough ER to cis-Golgi; GO:0048208 COPII vesicle coating; GO:0044699 single-organism process; GO:0048193 Golgi vesicle transport; GO:0006903 vesicle targeting; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0051649 establishment of localization in cell; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0051648 vesicle localization; GO:0048199 vesicle targeting, to, from or within Golgi; GO:0006886 intracellular protein transport; GO:0034613 cellular protein localization; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0051650 establishment of vesicle localization; GO:0071822 protein complex subunit organization; GO:0090114 COPII-coated vesicle budding; GO:0002474 antigen processing and presentation of peptide antigen via MHC class I; GO:0048002 antigen processing and presentation of peptide antigen; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0016050 vesicle organization; GO:0071702 organic substance transport; GO:0002376 immune system process; GO:0051656 establishment of organelle localization; GO:0002495 antigen processing and presentation of peptide antigen via MHC class II; GO:0043933 macromolecular complex subunit organization; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0019882 antigen processing and presentation; GO:0070727 cellular macromolecule localization; GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0006900 membrane budding; GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II; GO:0051179 localization; GO:0070271 protein complex biogenesis; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0071840 cellular component organization or biogenesis; ","GO:0030658 transport vesicle membrane; GO:0016020 membrane; GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network; GO:0005783 endoplasmic reticulum; GO:0031410 cytoplasmic vesicle; GO:0031090 organelle membrane; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0030662 coated vesicle membrane; GO:0044422 organelle part; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0098791 Golgi subcompartment; GO:0044431 Golgi apparatus part; GO:0043227 membrane-bounded organelle; GO:0005789 endoplasmic reticulum membrane; GO:0012507 ER to Golgi transport vesicle membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0032580 Golgi cisterna membrane; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012506 vesicle membrane; GO:0030134 ER to Golgi transport vesicle; GO:0012505 endomembrane system; GO:0005795 Golgi stack; GO:0005829 cytosol; GO:0030135 coated vesicle; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0044432 endoplasmic reticulum part; GO:0030133 transport vesicle; GO:0005794 Golgi apparatus; GO:0031985 Golgi cisterna; GO:0044444 cytoplasmic part; GO:0031984 organelle subcompartment; ","GO:1901265 nucleoside phosphate binding; GO:0001882 nucleoside binding; GO:0043167 ion binding; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0016787 hydrolase activity; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0003924 GTPase activity; GO:0043169 cation binding; GO:0046872 metal ion binding; GO:0032555 purine ribonucleotide binding; GO:0043168 anion binding; GO:0032561 guanyl ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0019001 guanyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0005525 GTP binding; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0036094 small molecule binding; ","K07953","SAR1; GTP-binding protein SAR1 [EC:3.6.5.-]","hsa05134 Legionellosis - Homo sapiens (human); hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human); ","IPR005225; IPR027417; ","Small GTP-binding protein domain; P-loop containing nucleoside triphosphate hydrolase; \r"]
["Q9Y6C2","EMILIN-1 OS=Homo sapiens OX=9606 GN=EMILIN1","EMILIN1",106.69,83.955,18.4,14,20,14,1.089,1.11,1.106,0.905,0.846,1.001,0.833,0.0638,"extracellular\r","GO:0007155 cell adhesion; GO:0022610 biological adhesion; ","GO:0031012 extracellular matrix; GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0005578 proteinaceous extracellular matrix; GO:0032991 macromolecular complex; GO:0043234 protein complex; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0005581 collagen trimer; GO:0043230 extracellular organelle; ","GO:0030023 extracellular matrix constituent conferring elasticity; GO:0005201 extracellular matrix structural constituent; GO:0005515 protein binding; GO:0042802 identical protein binding; GO:0005198 structural molecule activity; GO:0005488 binding; GO:0097493 structural molecule activity conferring elasticity; ",{"$nulls":3},"IPR008983; IPR011489; IPR001073; ","Tumour necrosis factor-like domain; EMI domain; C1q domain; \r"]
["Q9Y6C9","Mitochondrial carrier homolog 2 OS=Homo sapiens OX=9606 GN=MTCH2","MTCH2",33.331,3.9298,9.2,2,2,2,1.008,1.107,0.926,0.967,1.063,0.943,0.978,0.753,"extracellular\r","GO:0009116 nucleoside metabolic process; GO:0065008 regulation of biological quality; GO:0010941 regulation of cell death; GO:0032270 positive regulation of cellular protein metabolic process; GO:0045980 negative regulation of nucleotide metabolic process; GO:0044237 cellular metabolic process; GO:0045978 negative regulation of nucleoside metabolic process; GO:0008152 metabolic process; GO:0006091 generation of precursor metabolites and energy; GO:0044093 positive regulation of molecular function; GO:0019693 ribose phosphate metabolic process; GO:0032787 monocarboxylic acid metabolic process; GO:1902229 regulation of intrinsic apoptotic signaling pathway in response to DNA damage; GO:0090559 regulation of membrane permeability; GO:0033365 protein localization to organelle; GO:0008104 protein localization; GO:0010677 negative regulation of cellular carbohydrate metabolic process; GO:0052548 regulation of endopeptidase activity; GO:0097284 hepatocyte apoptotic process; GO:0042325 regulation of phosphorylation; GO:0051716 cellular response to stimulus; GO:0051174 regulation of phosphorus metabolic process; GO:0006089 lactate metabolic process; GO:0071214 cellular response to abiotic stimulus; GO:0010950 positive regulation of endopeptidase activity; GO:0072657 protein localization to membrane; GO:0080090 regulation of primary metabolic process; GO:0009894 regulation of catabolic process; GO:0051198 negative regulation of coenzyme metabolic process; GO:0044281 small molecule metabolic process; GO:0044763 single-organism cellular process; GO:0072521 purine-containing compound metabolic process; GO:0009205 purine ribonucleoside triphosphate metabolic process; GO:0048870 cell motility; GO:0031323 regulation of cellular metabolic process; GO:0048872 homeostasis of number of cells; GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0006810 transport; GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage; GO:0080135 regulation of cellular response to stress; GO:0051336 regulation of hydrolase activity; GO:0009161 ribonucleoside monophosphate metabolic process; GO:0050790 regulation of catalytic activity; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:0022900 electron transport chain; GO:0010604 positive regulation of macromolecule metabolic process; GO:2001244 positive regulation of intrinsic apoptotic signaling pathway; GO:0051172 negative regulation of nitrogen compound metabolic process; GO:0009126 purine nucleoside monophosphate metabolic process; GO:0072655 establishment of protein localization to mitochondrion; GO:0006140 regulation of nucleotide metabolic process; GO:0010952 positive regulation of peptidase activity; GO:0043068 positive regulation of programmed cell death; GO:0043436 oxoacid metabolic process; GO:0050794 regulation of cellular process; GO:0016310 phosphorylation; GO:2001056 positive regulation of cysteine-type endopeptidase activity; GO:1901615 organic hydroxy compound metabolic process; GO:0007006 mitochondrial membrane organization; GO:2001020 regulation of response to DNA damage stimulus; GO:0009259 ribonucleotide metabolic process; GO:0009628 response to abiotic stimulus; GO:0043067 regulation of programmed cell death; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:0010917 negative regulation of mitochondrial membrane potential; GO:0046483 heterocycle metabolic process; GO:1902578 single-organism localization; GO:0006139 nucleobase-containing compound metabolic process; GO:0051345 positive regulation of hydrolase activity; GO:0051171 regulation of nitrogen compound metabolic process; GO:1901135 carbohydrate derivative metabolic process; GO:0061484 hematopoietic stem cell homeostasis; GO:1902580 single-organism cellular localization; GO:0034613 cellular protein localization; GO:0009119 ribonucleoside metabolic process; GO:0009966 regulation of signal transduction; GO:0090150 establishment of protein localization to membrane; GO:1902531 regulation of intracellular signal transduction; GO:0009141 nucleoside triphosphate metabolic process; GO:0030162 regulation of proteolysis; GO:0006109 regulation of carbohydrate metabolic process; GO:1903579 negative regulation of ATP metabolic process; GO:0044238 primary metabolic process; GO:0009892 negative regulation of metabolic process; GO:0006163 purine nucleotide metabolic process; GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process; GO:0045184 establishment of protein localization; GO:0045912 negative regulation of carbohydrate metabolic process; GO:0051247 positive regulation of protein metabolic process; GO:0006793 phosphorus metabolic process; GO:0006996 organelle organization; GO:1900543 negative regulation of purine nucleotide metabolic process; GO:0031325 positive regulation of cellular metabolic process; GO:0061024 membrane organization; GO:0019637 organophosphate metabolic process; GO:0006928 movement of cell or subcellular component; GO:0012501 programmed cell death; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0045936 negative regulation of phosphate metabolic process; GO:1901564 organonitrogen compound metabolic process; GO:0009123 nucleoside monophosphate metabolic process; GO:0043467 regulation of generation of precursor metabolites and energy; GO:0042278 purine nucleoside metabolic process; GO:0072594 establishment of protein localization to organelle; GO:0009167 purine ribonucleoside monophosphate metabolic process; GO:0051674 localization of cell; GO:0009117 nucleotide metabolic process; GO:0006839 mitochondrial transport; GO:0023051 regulation of signaling; GO:1902533 positive regulation of intracellular signal transduction; GO:0044699 single-organism process; GO:0006796 phosphate-containing compound metabolic process; GO:0051234 establishment of localization; GO:0051196 regulation of coenzyme metabolic process; GO:2001233 regulation of apoptotic signaling pathway; GO:0051649 establishment of localization in cell; GO:0010646 regulation of cell communication; GO:0009893 positive regulation of metabolic process; GO:0006753 nucleoside phosphate metabolic process; GO:0006915 apoptotic process; GO:0007005 mitochondrion organization; GO:0009314 response to radiation; GO:0033036 macromolecule localization; GO:1904019 epithelial cell apoptotic process; GO:2001022 positive regulation of response to DNA damage stimulus; GO:0051193 regulation of cofactor metabolic process; GO:2000116 regulation of cysteine-type endopeptidase activity; GO:0010675 regulation of cellular carbohydrate metabolic process; GO:0006110 regulation of glycolytic process; GO:0055114 oxidation-reduction process; GO:0043470 regulation of carbohydrate catabolic process; GO:0006119 oxidative phosphorylation; GO:1901360 organic cyclic compound metabolic process; GO:0048522 positive regulation of cellular process; GO:0009199 ribonucleoside triphosphate metabolic process; GO:0010942 positive regulation of cell death; GO:0042391 regulation of membrane potential; GO:1902589 single-organism organelle organization; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0015980 energy derivation by oxidation of organic compounds; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0019220 regulation of phosphate metabolic process; GO:1901657 glycosyl compound metabolic process; GO:0040011 locomotion; GO:0006082 organic acid metabolic process; GO:0052547 regulation of peptidase activity; GO:0051195 negative regulation of cofactor metabolic process; GO:0016043 cellular component organization; GO:0016477 cell migration; GO:0006725 cellular aromatic compound metabolic process; GO:0042773 ATP synthesis coupled electron transport; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0048285 organelle fission; GO:0009118 regulation of nucleoside metabolic process; GO:0043065 positive regulation of apoptotic process; GO:0022904 respiratory electron transport chain; GO:0031324 negative regulation of cellular metabolic process; GO:0050896 response to stimulus; GO:0071704 organic substance metabolic process; GO:0042592 homeostatic process; GO:0045862 positive regulation of proteolysis; GO:0046902 regulation of mitochondrial membrane permeability; GO:0090151 establishment of protein localization to mitochondrial membrane; GO:0042326 negative regulation of phosphorylation; GO:0023056 positive regulation of signaling; GO:2001235 positive regulation of apoptotic signaling pathway; GO:0009895 negative regulation of catabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0010647 positive regulation of cell communication; GO:0055086 nucleobase-containing small molecule metabolic process; GO:0009144 purine nucleoside triphosphate metabolic process; GO:0045820 negative regulation of glycolytic process; GO:0071478 cellular response to radiation; GO:0009987 cellular process; GO:1903578 regulation of ATP metabolic process; GO:0046034 ATP metabolic process; GO:0008637 apoptotic mitochondrial changes; GO:0035701 hematopoietic stem cell migration; GO:0006807 nitrogen compound metabolic process; GO:0044802 single-organism membrane organization; GO:0045934 negative regulation of nucleobase-containing compound metabolic process; GO:0070585 protein localization to mitochondrion; GO:0090152 establishment of protein localization to mitochondrial membrane involved in mitochondrial fission; GO:0045333 cellular respiration; GO:0048518 positive regulation of biological process; GO:0000266 mitochondrial fission; GO:0051641 cellular localization; GO:0043085 positive regulation of catalytic activity; GO:1900542 regulation of purine nucleotide metabolic process; GO:0046128 purine ribonucleoside metabolic process; GO:0070727 cellular macromolecule localization; GO:0008219 cell death; GO:0051246 regulation of protein metabolic process; GO:0010563 negative regulation of phosphorus metabolic process; GO:0045837 negative regulation of membrane potential; GO:2001242 regulation of intrinsic apoptotic signaling pathway; GO:0019752 carboxylic acid metabolic process; GO:0009150 purine ribonucleotide metabolic process; GO:0009967 positive regulation of signal transduction; GO:0042775 mitochondrial ATP synthesis coupled electron transport; GO:0051881 regulation of mitochondrial membrane potential; GO:0042981 regulation of apoptotic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0016020 membrane; GO:0044421 extracellular region part; GO:0019867 outer membrane; GO:0031090 organelle membrane; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0031224 intrinsic component of membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0070062 extracellular exosome; GO:0005740 mitochondrial envelope; GO:0044425 membrane part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0019866 organelle inner membrane; GO:1903561 extracellular vesicle; GO:0031968 organelle outer membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0044429 mitochondrial part; GO:0005741 mitochondrial outer membrane; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0016021 integral component of membrane; GO:0005576 extracellular region; GO:0005739 mitochondrion; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0031975 envelope; GO:0043230 extracellular organelle; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ",null,"K17885",null,null,"IPR023395; ","Mitochondrial carrier domain; \r"]
["Q9Y6D6","Brefeldin A-inhibited guanine nucleotide-exchange protein 1 OS=Homo sapiens OX=9606 GN=ARFGEF1","ARFGEF1",208.76,19.674,4.5,9,12,3,1.043,0.938,0.9,1.129,0.954,1.045,1.086,0.28,"cytoplasm\r","GO:0065008 regulation of biological quality; GO:0032270 positive regulation of cellular protein metabolic process; GO:0051896 regulation of protein kinase B signaling; GO:0009891 positive regulation of biosynthetic process; GO:0030832 regulation of actin filament length; GO:0015031 protein transport; GO:0032535 regulation of cellular component size; GO:0044093 positive regulation of molecular function; GO:0090303 positive regulation of wound healing; GO:0051493 regulation of cytoskeleton organization; GO:0008104 protein localization; GO:0051056 regulation of small GTPase mediated signal transduction; GO:0031333 negative regulation of protein complex assembly; GO:0060050 positive regulation of protein glycosylation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0007399 nervous system development; GO:0080090 regulation of primary metabolic process; GO:0048699 generation of neurons; GO:0010559 regulation of glycoprotein biosynthetic process; GO:0044763 single-organism cellular process; GO:0090283 regulation of protein glycosylation in Golgi; GO:0031323 regulation of cellular metabolic process; GO:0043086 negative regulation of catalytic activity; GO:0032501 multicellular organismal process; GO:0006810 transport; GO:0051336 regulation of hydrolase activity; GO:0007030 Golgi organization; GO:0050790 regulation of catalytic activity; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:2000114 regulation of establishment of cell polarity; GO:0010604 positive regulation of macromolecule metabolic process; GO:0030837 negative regulation of actin filament polymerization; GO:1902903 regulation of supramolecular fiber organization; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:1903036 positive regulation of response to wounding; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0032956 regulation of actin cytoskeleton organization; GO:0031399 regulation of protein modification process; GO:0048523 negative regulation of cellular process; GO:0080134 regulation of response to stress; GO:0048519 negative regulation of biological process; GO:1902578 single-organism localization; GO:0051345 positive regulation of hydrolase activity; GO:0009889 regulation of biosynthetic process; GO:0007275 multicellular organism development; GO:0009966 regulation of signal transduction; GO:1902531 regulation of intracellular signal transduction; GO:0043547 positive regulation of GTPase activity; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:1903018 regulation of glycoprotein metabolic process; GO:0032970 regulation of actin filament-based process; GO:0071702 organic substance transport; GO:0045184 establishment of protein localization; GO:0008064 regulation of actin polymerization or depolymerization; GO:0030182 neuron differentiation; GO:0051247 positive regulation of protein metabolic process; GO:0061041 regulation of wound healing; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0032012 regulation of ARF protein signal transduction; GO:0051179 localization; GO:0048584 positive regulation of response to stimulus; GO:0031328 positive regulation of cellular biosynthetic process; GO:1903034 regulation of response to wounding; GO:0006887 exocytosis; GO:0030833 regulation of actin filament polymerization; GO:0010256 endomembrane system organization; GO:0023051 regulation of signaling; GO:0048869 cellular developmental process; GO:0048666 neuron development; GO:0051129 negative regulation of cellular component organization; GO:1902533 positive regulation of intracellular signal transduction; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0051234 establishment of localization; GO:1903020 positive regulation of glycoprotein metabolic process; GO:0010646 regulation of cell communication; GO:0009893 positive regulation of metabolic process; GO:0032271 regulation of protein polymerization; GO:0033036 macromolecule localization; GO:0034260 negative regulation of GTPase activity; GO:0090284 positive regulation of protein glycosylation in Golgi; GO:0032502 developmental process; GO:0032878 regulation of establishment or maintenance of cell polarity; GO:0031326 regulation of cellular biosynthetic process; GO:0051494 negative regulation of cytoskeleton organization; GO:0048522 positive regulation of cellular process; GO:0010639 negative regulation of organelle organization; GO:0050789 regulation of biological process; GO:0032268 regulation of cellular protein metabolic process; GO:0043254 regulation of protein complex assembly; GO:0030030 cell projection organization; GO:0032940 secretion by cell; GO:1902904 negative regulation of supramolecular fiber organization; GO:0043087 regulation of GTPase activity; GO:0065009 regulation of molecular function; GO:0019222 regulation of metabolic process; GO:0044092 negative regulation of molecular function; GO:0048856 anatomical structure development; GO:0016043 cellular component organization; GO:0060255 regulation of macromolecule metabolic process; GO:0060049 regulation of protein glycosylation; GO:0044087 regulation of cellular component biogenesis; GO:0046578 regulation of Ras protein signal transduction; GO:0051346 negative regulation of hydrolase activity; GO:0048468 cell development; GO:0030154 cell differentiation; GO:0023056 positive regulation of signaling; GO:0010647 positive regulation of cell communication; GO:0009987 cellular process; GO:0010560 positive regulation of glycoprotein biosynthetic process; GO:0051897 positive regulation of protein kinase B signaling; GO:0031401 positive regulation of protein modification process; GO:0033043 regulation of organelle organization; GO:0010556 regulation of macromolecule biosynthetic process; GO:0031175 neuron projection development; GO:0048518 positive regulation of biological process; GO:0043085 positive regulation of catalytic activity; GO:0051246 regulation of protein metabolic process; GO:0044767 single-organism developmental process; GO:0090066 regulation of anatomical structure size; GO:0009967 positive regulation of signal transduction; GO:0051128 regulation of cellular component organization; GO:0032272 negative regulation of protein polymerization; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0031090 organelle membrane; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0031974 membrane-enclosed lumen; GO:0005654 nucleoplasm; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0098791 Golgi subcompartment; GO:0044431 Golgi apparatus part; GO:0048471 perinuclear region of cytoplasm; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0043229 intracellular organelle; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0031981 nuclear lumen; GO:0012505 endomembrane system; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0016363 nuclear matrix; GO:0005802 trans-Golgi network; GO:1990904 ribonucleoprotein complex; GO:0034399 nuclear periphery; GO:0030532 small nuclear ribonucleoprotein complex; GO:0030529 intracellular ribonucleoprotein complex; GO:0005794 Golgi apparatus; GO:0031984 organelle subcompartment; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:0051018 protein kinase A binding; GO:0008092 cytoskeletal protein binding; GO:0005086 ARF guanyl-nucleotide exchange factor activity; GO:0005085 guanyl-nucleotide exchange factor activity; GO:0034237 protein kinase A regulatory subunit binding; GO:0005488 binding; GO:0005515 protein binding; GO:0017022 myosin binding; GO:0098772 molecular function regulator; ","K18442","ARFGEF; brefeldin A-inhibited guanine nucleotide-exchange protein","hsa04144 Endocytosis - Homo sapiens (human); ","IPR023394; IPR011989; IPR000904; IPR032691; IPR032629; IPR016024; IPR015403; ","\"Sec7 domain, alpha orthogonal bundle; Armadillo-like helical; Sec7 domain; Guanine nucleotide exchange factor, N-terminal; Mon2, dimerisation and cyclophilin-binding domain; Armadillo-type fold; Sec7, C-terminal; \"\r"]
["Q9Y6E0","Serine/threonine-protein kinase 24 OS=Homo sapiens OX=9606 GN=STK24","STK24",49.307,75.65,32.7,12,19,12,0.945,0.945,0.966,1.031,1.082,1.059,1.111,2.66E-3,"cytoplasm\r","GO:0044700 single organism signaling; GO:0048869 cellular developmental process; GO:0022008 neurogenesis; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0006796 phosphate-containing compound metabolic process; GO:0040013 negative regulation of locomotion; GO:0007165 signal transduction; GO:0008152 metabolic process; GO:0007154 cell communication; GO:0032879 regulation of localization; GO:0046777 protein autophosphorylation; GO:0006915 apoptotic process; GO:0006979 response to oxidative stress; GO:0010035 response to inorganic substance; GO:0034599 cellular response to oxidative stress; GO:0043170 macromolecule metabolic process; GO:0019538 protein metabolic process; GO:0070570 regulation of neuron projection regeneration; GO:0070887 cellular response to chemical stimulus; GO:0007399 nervous system development; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0048699 generation of neurons; GO:0000302 response to reactive oxygen species; GO:0044763 single-organism cellular process; GO:2000146 negative regulation of cell motility; GO:0023052 signaling; GO:0032501 multicellular organismal process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0080135 regulation of cellular response to stress; GO:0045664 regulation of neuron differentiation; GO:0044710 single-organism metabolic process; GO:0048583 regulation of response to stimulus; GO:0044260 cellular macromolecule metabolic process; GO:0097194 execution phase of apoptosis; GO:0006464 cellular protein modification process; GO:0036211 protein modification process; GO:0048856 anatomical structure development; GO:0010975 regulation of neuron projection development; GO:2000026 regulation of multicellular organismal development; GO:0051271 negative regulation of cellular component movement; GO:0050794 regulation of cellular process; GO:0016310 phosphorylation; GO:0033554 cellular response to stress; GO:0044707 single-multicellular organism process; GO:0097190 apoptotic signaling pathway; GO:0044267 cellular protein metabolic process; GO:1901700 response to oxygen-containing compound; GO:0031344 regulation of cell projection organization; GO:0080134 regulation of response to stress; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0097193 intrinsic apoptotic signaling pathway; GO:0051239 regulation of multicellular organismal process; GO:0071704 organic substance metabolic process; GO:0030154 cell differentiation; GO:0006468 protein phosphorylation; GO:2000145 regulation of cell motility; GO:0007275 multicellular organism development; GO:0048679 regulation of axon regeneration; GO:0009987 cellular process; GO:0045595 regulation of cell differentiation; GO:0023014 signal transduction by protein phosphorylation; GO:0006950 response to stress; GO:0035556 intracellular signal transduction; GO:0051270 regulation of cellular component movement; GO:0048731 system development; GO:0060284 regulation of cell development; GO:0051960 regulation of nervous system development; GO:0036473 cell death in response to oxidative stress; GO:0032101 regulation of response to external stimulus; GO:0030334 regulation of cell migration; GO:0044238 primary metabolic process; GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress; GO:0006793 phosphorus metabolic process; GO:0008219 cell death; GO:0030336 negative regulation of cell migration; GO:0044767 single-organism developmental process; GO:0042542 response to hydrogen peroxide; GO:0051128 regulation of cellular component organization; GO:0012501 programmed cell death; GO:0043412 macromolecule modification; GO:0040012 regulation of locomotion; GO:0050793 regulation of developmental process; GO:1903034 regulation of response to wounding; GO:0050767 regulation of neurogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0044421 extracellular region part; GO:0043232 intracellular non-membrane-bounded organelle; GO:0031982 vesicle; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005730 nucleolus; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0031974 membrane-enclosed lumen; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; GO:0043233 organelle lumen; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0016773 phosphotransferase activity, alcohol group as acceptor; GO:0005515 protein binding; GO:0004672 protein kinase activity; GO:0004702 signal transducer, downstream of receptor, with serine/threonine kinase activity; GO:0004871 signal transducer activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0016301 kinase activity; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0045296 cadherin binding; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0032549 ribonucleoside binding; GO:0050839 cell adhesion molecule binding; GO:0097367 carbohydrate derivative binding; GO:0005057 signal transducer activity, downstream of receptor; GO:0046872 metal ion binding; GO:0032555 purine ribonucleotide binding; GO:0004674 protein serine/threonine kinase activity; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K08838",null,null,"IPR000719; IPR011009; ","Protein kinase domain; Protein kinase-like domain; \r"]
["Q9Y6E2","Basic leucine zipper and W2 domain-containing protein 2 OS=Homo sapiens OX=9606 GN=BZW2","BZW2",48.162,46.082,20.5,8,10,7,0.763,0.944,0.823,1.112,1.206,1.201,1.391,0.0079,"nucleus\r","GO:0007399 nervous system development; GO:0032502 developmental process; GO:0044707 single-multicellular organism process; GO:0030154 cell differentiation; GO:0048731 system development; GO:0044767 single-organism developmental process; GO:0048869 cellular developmental process; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0007275 multicellular organism development; GO:0009987 cellular process; GO:0048856 anatomical structure development; GO:0032501 multicellular organismal process; ","GO:0016020 membrane; GO:0044424 intracellular part; GO:0005623 cell; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; ","GO:0050839 cell adhesion molecule binding; GO:0005515 protein binding; GO:0005488 binding; GO:0045296 cadherin binding; ",{"$nulls":3},"IPR003307; IPR016024; IPR016021; ","W2 domain; Armadillo-type fold; MIF4G-like domain; \r"]
["Q9Y6G5","COMM domain-containing protein 10 OS=Homo sapiens OX=9606 GN=COMMD10","COMMD10",22.966,10.186,17.8,3,3,3,0.99,0.979,1.112,1.096,0.886,0.95,0.952,0.526,"cytoplasm\r","GO:0050794 regulation of cellular process; GO:0006725 cellular aromatic compound metabolic process; GO:0097659 nucleic acid-templated transcription; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:0071704 organic substance metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0043170 macromolecule metabolic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0006355 regulation of transcription, DNA-templated; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0034654 nucleobase-containing compound biosynthetic process; GO:1901360 organic cyclic compound metabolic process; GO:0006807 nitrogen compound metabolic process; GO:0010556 regulation of macromolecule biosynthetic process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0044238 primary metabolic process; GO:0051252 regulation of RNA metabolic process; GO:1901576 organic substance biosynthetic process; GO:0044249 cellular biosynthetic process; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0034645 cellular macromolecule biosynthetic process; GO:0090304 nucleic acid metabolic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006351 transcription, DNA-templated; GO:0044260 cellular macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:0010467 gene expression; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0065007 biological regulation; ","GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0005634 nucleus; GO:0044464 cell part; GO:0005622 intracellular; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0043227 membrane-bounded organelle; GO:0005623 cell; ","GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR017920; ","COMM domain; \r"]
["Q9Y6G9","Cytoplasmic dynein 1 light intermediate chain 1 OS=Homo sapiens OX=9606 GN=DYNC1LI1","DYNC1LI1",56.578,47.259,22.8,10,11,10,0.997,0.929,0.95,1.039,1.047,1.008,1.076,0.0371,"cytoplasm\r","GO:0045321 leukocyte activation; GO:0007067 mitotic nuclear division; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0010564 regulation of cell cycle process; GO:0030071 regulation of mitotic metaphase/anaphase transition; GO:0051234 establishment of localization; GO:0051783 regulation of nuclear division; GO:0051649 establishment of localization in cell; GO:1901990 regulation of mitotic cell cycle phase transition; GO:0090068 positive regulation of cell cycle process; GO:0044419 interspecies interaction between organisms; GO:0002478 antigen processing and presentation of exogenous peptide antigen; GO:0051726 regulation of cell cycle; GO:0002274 myeloid leukocyte activation; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0000278 mitotic cell cycle; GO:0002443 leukocyte mediated immunity; GO:0033045 regulation of sister chromatid segregation; GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint; GO:1905818 regulation of chromosome separation; GO:0048002 antigen processing and presentation of peptide antigen; GO:0002446 neutrophil mediated immunity; GO:0033047 regulation of mitotic sister chromatid segregation; GO:0007088 regulation of mitotic nuclear division; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0002495 antigen processing and presentation of peptide antigen via MHC class II; GO:0002444 myeloid leukocyte mediated immunity; GO:0051704 multi-organism process; GO:0006810 transport; GO:0019884 antigen processing and presentation of exogenous antigen; GO:0000226 microtubule cytoskeleton organization; GO:0050789 regulation of biological process; GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; GO:0045931 positive regulation of mitotic cell cycle; GO:0032940 secretion by cell; GO:1903504 regulation of mitotic spindle checkpoint; GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II; GO:0051301 cell division; GO:0043299 leukocyte degranulation; GO:1901978 positive regulation of cell cycle checkpoint; GO:0090231 regulation of spindle checkpoint; GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint; GO:0050794 regulation of cellular process; GO:0046907 intracellular transport; GO:0016043 cellular component organization; GO:0007346 regulation of mitotic cell cycle; GO:0002283 neutrophil activation involved in immune response; GO:0002252 immune effector process; GO:0048285 organelle fission; GO:0048193 Golgi vesicle transport; GO:0050896 response to stimulus; GO:1903047 mitotic cell cycle process; GO:1902578 single-organism localization; GO:0002275 myeloid cell activation involved in immune response; GO:0016032 viral process; GO:1901987 regulation of cell cycle phase transition; GO:0090232 positive regulation of spindle checkpoint; GO:0036230 granulocyte activation; GO:0007010 cytoskeleton organization; GO:0009987 cellular process; GO:0045787 positive regulation of cell cycle; GO:0051983 regulation of chromosome segregation; GO:1901976 regulation of cell cycle checkpoint; GO:0016192 vesicle-mediated transport; GO:0033043 regulation of organelle organization; GO:1902099 regulation of metaphase/anaphase transition of cell cycle; GO:0002376 immune system process; GO:0043312 neutrophil degranulation; GO:0007017 microtubule-based process; GO:0002263 cell activation involved in immune response; GO:0048518 positive regulation of biological process; GO:0033044 regulation of chromosome organization; GO:0051641 cellular localization; GO:0002366 leukocyte activation involved in immune response; GO:0019882 antigen processing and presentation; GO:0007018 microtubule-based movement; GO:0045055 regulated exocytosis; GO:0042119 neutrophil activation; GO:0010965 regulation of mitotic sister chromatid separation; GO:0006996 organelle organization; GO:0006928 movement of cell or subcellular component; GO:0001775 cell activation; GO:0000280 nuclear division; GO:0022402 cell cycle process; GO:0051128 regulation of cellular component organization; GO:0051179 localization; GO:0006955 immune response; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0007049 cell cycle; GO:0006887 exocytosis; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0016020 membrane; GO:0005874 microtubule; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0099512 supramolecular fiber; GO:0005623 cell; GO:0099080 supramolecular complex; GO:0000777 condensed chromosome kinetochore; GO:0044422 organelle part; GO:0044427 chromosomal part; GO:0043228 non-membrane-bounded organelle; GO:0000793 condensed chromosome; GO:0005856 cytoskeleton; GO:0005815 microtubule organizing center; GO:1902494 catalytic complex; GO:0015630 microtubule cytoskeleton; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0099503 secretory vesicle; GO:0005694 chromosome; GO:0030141 secretory granule; GO:0043227 membrane-bounded organelle; GO:0000776 kinetochore; GO:0097708 intracellular vesicle; GO:0043229 intracellular organelle; GO:0099513 polymeric cytoskeletal fiber; GO:0000922 spindle pole; GO:0098588 bounding membrane of organelle; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0000779 condensed chromosome, centromeric region; GO:0070820 tertiary granule; GO:0044446 intracellular organelle part; GO:0012506 vesicle membrane; GO:0012505 endomembrane system; GO:0005875 microtubule associated complex; GO:0030286 dynein complex; GO:0005868 cytoplasmic dynein complex; GO:0005829 cytosol; GO:0005819 spindle; GO:0005886 plasma membrane; GO:0099081 supramolecular polymer; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0098687 chromosomal region; GO:0030667 secretory granule membrane; GO:0101003 ficolin-1-rich granule membrane; GO:0005813 centrosome; GO:0000775 chromosome, centromeric region; GO:0043234 protein complex; GO:0044444 cytoplasmic part; ","GO:1901265 nucleoside phosphate binding; GO:0003774 motor activity; GO:0016817 hydrolase activity, acting on acid anhydrides; GO:0005515 protein binding; GO:0016787 hydrolase activity; GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0019003 GDP binding; GO:0016462 pyrophosphatase activity; GO:0032553 ribonucleotide binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0003777 microtubule motor activity; GO:0019001 guanyl nucleotide binding; GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; GO:0045504 dynein heavy chain binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0017076 purine nucleotide binding; GO:0003723 RNA binding; GO:0005524 ATP binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0017111 nucleoside-triphosphatase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0003676 nucleic acid binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0032561 guanyl ribonucleotide binding; GO:0036094 small molecule binding; ","K10416","DYNC1LI; dynein light intermediate chain 1, cytosolic","hsa05132 Salmonella infection - Homo sapiens (human); hsa04145 Phagosome - Homo sapiens (human); hsa04962 Vasopressin-regulated water reabsorption - Homo sapiens (human); ","IPR027417; ","P-loop containing nucleoside triphosphate hydrolase; \r"]
["Q9Y6H1","Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 OS=Homo sapiens OX=9606 GN=CHCHD2","CHCHD2",15.512,8.3498,19.9,3,4,3,0.977,0.967,0.991,0.955,1.031,1.082,1.045,0.31,"mitochondria\r","GO:0097659 nucleic acid-templated transcription; GO:0009891 positive regulation of biosynthetic process; GO:0009058 biosynthetic process; GO:0044237 cellular metabolic process; GO:2001141 regulation of RNA biosynthetic process; GO:0008152 metabolic process; GO:0009893 positive regulation of metabolic process; GO:0051173 positive regulation of nitrogen compound metabolic process; GO:0007005 mitochondrion organization; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0043170 macromolecule metabolic process; GO:0010468 regulation of gene expression; GO:0018130 heterocycle biosynthetic process; GO:0031326 regulation of cellular biosynthetic process; GO:0080090 regulation of primary metabolic process; GO:0045893 positive regulation of transcription, DNA-templated; GO:0048522 positive regulation of cellular process; GO:1901360 organic cyclic compound metabolic process; GO:0032774 RNA biosynthetic process; GO:0031323 regulation of cellular metabolic process; GO:0016070 RNA metabolic process; GO:1903506 regulation of nucleic acid-templated transcription; GO:0050789 regulation of biological process; GO:0080135 regulation of cellular response to stress; GO:0090304 nucleic acid metabolic process; GO:0006351 transcription, DNA-templated; GO:0048583 regulation of response to stimulus; GO:0010557 positive regulation of macromolecule biosynthetic process; GO:0044260 cellular macromolecule metabolic process; GO:0010604 positive regulation of macromolecule metabolic process; GO:0019222 regulation of metabolic process; GO:1901362 organic cyclic compound biosynthetic process; GO:2000112 regulation of cellular macromolecule biosynthetic process; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0006725 cellular aromatic compound metabolic process; GO:0060255 regulation of macromolecule metabolic process; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0080134 regulation of response to stress; GO:0071704 organic substance metabolic process; GO:1900037 regulation of cellular response to hypoxia; GO:0046483 heterocycle metabolic process; GO:0019438 aromatic compound biosynthetic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0010628 positive regulation of gene expression; GO:0009889 regulation of biosynthetic process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:1902680 positive regulation of RNA biosynthetic process; GO:0009059 macromolecule biosynthetic process; GO:0009987 cellular process; GO:0051254 positive regulation of RNA metabolic process; GO:0006355 regulation of transcription, DNA-templated; GO:0034654 nucleobase-containing compound biosynthetic process; GO:0006807 nitrogen compound metabolic process; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0010556 regulation of macromolecule biosynthetic process; GO:0044238 primary metabolic process; GO:1901576 organic substance biosynthetic process; GO:0051252 regulation of RNA metabolic process; GO:0048518 positive regulation of biological process; GO:0044249 cellular biosynthetic process; GO:1903508 positive regulation of nucleic acid-templated transcription; GO:0034645 cellular macromolecule biosynthetic process; GO:0044271 cellular nitrogen compound biosynthetic process; GO:0006996 organelle organization; GO:0031325 positive regulation of cellular metabolic process; GO:0045935 positive regulation of nucleobase-containing compound metabolic process; GO:0010467 gene expression; GO:0031328 positive regulation of cellular biosynthetic process; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; ","GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0044446 intracellular organelle part; GO:0031967 organelle envelope; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0031974 membrane-enclosed lumen; GO:0005740 mitochondrial envelope; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0031970 organelle envelope lumen; GO:0005758 mitochondrial intermembrane space; GO:0005622 intracellular; GO:0044464 cell part; GO:0031975 envelope; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003677 DNA binding; GO:0005488 binding; GO:0003676 nucleic acid binding; GO:0005515 protein binding; GO:0043565 sequence-specific DNA binding; GO:0008134 transcription factor binding; ",{"$nulls":3},"IPR010625; ","CHCH; \r"]
["Q9Y6I3","Epsin-1 OS=Homo sapiens OX=9606 GN=EPN1","EPN1",60.293,53.533,13.7,6,7,6,1.034,0.979,1.009,1.113,0.959,0.999,1.016,0.776,"nucleus\r","GO:0044700 single organism signaling; GO:0000003 reproduction; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0044707 single-multicellular organism process; GO:0009968 negative regulation of signal transduction; GO:0007166 cell surface receptor signaling pathway; GO:0022414 reproductive process; GO:0048568 embryonic organ development; GO:0043009 chordate embryonic development; GO:1901185 negative regulation of ERBB signaling pathway; GO:0023051 regulation of signaling; GO:0044699 single-organism process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0050896 response to stimulus; GO:0051234 establishment of localization; GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway; GO:0007565 female pregnancy; GO:0007165 signal transduction; GO:0023057 negative regulation of signaling; GO:0010646 regulation of cell communication; GO:0007154 cell communication; GO:0010648 negative regulation of cell communication; GO:1901184 regulation of ERBB signaling pathway; GO:0044706 multi-multicellular organism process; GO:0007275 multicellular organism development; GO:0009790 embryo development; GO:0007219 Notch signaling pathway; GO:0009987 cellular process; GO:0009966 regulation of signal transduction; GO:0032502 developmental process; GO:0051716 cellular response to stimulus; GO:0048731 system development; GO:0016192 vesicle-mediated transport; GO:0009792 embryo development ending in birth or egg hatching; GO:0048585 negative regulation of response to stimulus; GO:0023052 signaling; GO:0006897 endocytosis; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0006810 transport; GO:0048513 animal organ development; GO:0050789 regulation of biological process; GO:0001701 in utero embryonic development; GO:0044767 single-organism developmental process; GO:0061024 membrane organization; GO:0048583 regulation of response to stimulus; GO:0044703 multi-organism reproductive process; GO:0042058 regulation of epidermal growth factor receptor signaling pathway; GO:0051179 localization; GO:0048856 anatomical structure development; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0071944 cell periphery; GO:0005737 cytoplasm; GO:0012505 endomembrane system; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005886 plasma membrane; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005634 nucleus; GO:0005622 intracellular; GO:0044464 cell part; GO:0044425 membrane part; GO:0098805 whole membrane; GO:0098589 membrane region; GO:0005905 clathrin-coated pit; GO:0043227 membrane-bounded organelle; GO:0044444 cytoplasmic part; ","GO:0008289 lipid binding; GO:0005515 protein binding; GO:0005488 binding; ","K12471","EPN; epsin","hsa04144 Endocytosis - Homo sapiens (human); ","IPR013809; IPR008942; ","ENTH  domain; ENTH/VHS; \r"]
["Q9Y6K5","2'-5'-oligoadenylate synthase 3 OS=Homo sapiens OX=9606 GN=OAS3","OAS3",121.17,14.625,6.3,6,6,6,0.768,0.745,0.774,1.229,1.254,1.208,1.614,3.61e-06,"cyto_nucl\r","GO:0044700 single organism signaling; GO:0007166 cell surface receptor signaling pathway; GO:0098542 defense response to other organism; GO:0071346 cellular response to interferon-gamma; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0044237 cellular metabolic process; GO:0071345 cellular response to cytokine stimulus; GO:0009607 response to biotic stimulus; GO:0060333 interferon-gamma-mediated signaling pathway; GO:0009605 response to external stimulus; GO:0008152 metabolic process; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0044419 interspecies interaction between organisms; GO:0070887 cellular response to chemical stimulus; GO:0048525 negative regulation of viral process; GO:0051716 cellular response to stimulus; GO:0034097 response to cytokine; GO:0080090 regulation of primary metabolic process; GO:0060700 regulation of ribonuclease activity; GO:1901360 organic cyclic compound metabolic process; GO:0034340 response to type I interferon; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0045069 regulation of viral genome replication; GO:0031323 regulation of cellular metabolic process; GO:0023052 signaling; GO:0051704 multi-organism process; GO:0042221 response to chemical; GO:0050789 regulation of biological process; GO:0051607 defense response to virus; GO:0051336 regulation of hydrolase activity; GO:0050790 regulation of catalytic activity; GO:0019222 regulation of metabolic process; GO:0065009 regulation of molecular function; GO:0006952 defense response; GO:0009615 response to virus; GO:0050794 regulation of cellular process; GO:0060337 type I interferon signaling pathway; GO:0006725 cellular aromatic compound metabolic process; GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism; GO:0002252 immune effector process; GO:0060255 regulation of macromolecule metabolic process; GO:0071310 cellular response to organic substance; GO:0019219 regulation of nucleobase-containing compound metabolic process; GO:0048523 negative regulation of cellular process; GO:0048519 negative regulation of biological process; GO:0043207 response to external biotic stimulus; GO:0050896 response to stimulus; GO:0051707 response to other organism; GO:0045087 innate immune response; GO:0071704 organic substance metabolic process; GO:1903901 negative regulation of viral life cycle; GO:0032069 regulation of nuclease activity; GO:0046483 heterocycle metabolic process; GO:0006139 nucleobase-containing compound metabolic process; GO:0016032 viral process; GO:0051171 regulation of nitrogen compound metabolic process; GO:0034641 cellular nitrogen compound metabolic process; GO:0071357 cellular response to type I interferon; GO:0019221 cytokine-mediated signaling pathway; GO:0009987 cellular process; GO:0006950 response to stress; GO:0043900 regulation of multi-organism process; GO:0050792 regulation of viral process; GO:0006807 nitrogen compound metabolic process; GO:0002376 immune system process; GO:0010033 response to organic substance; GO:0045071 negative regulation of viral genome replication; GO:0034341 response to interferon-gamma; GO:0044238 primary metabolic process; GO:0051252 regulation of RNA metabolic process; GO:0043901 negative regulation of multi-organism process; GO:0006955 immune response; GO:1903900 regulation of viral life cycle; GO:0065007 biological regulation; ","GO:0043229 intracellular organelle; GO:0016020 membrane; GO:0005615 extracellular space; GO:0044421 extracellular region part; GO:0071944 cell periphery; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0031981 nuclear lumen; GO:0044424 intracellular part; GO:0005829 cytosol; GO:0005623 cell; GO:0005576 extracellular region; GO:0044422 organelle part; GO:0005886 plasma membrane; GO:0031974 membrane-enclosed lumen; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0005654 nucleoplasm; GO:0005634 nucleus; GO:0070013 intracellular organelle lumen; GO:0005622 intracellular; GO:0044464 cell part; GO:0043227 membrane-bounded organelle; GO:0043233 organelle lumen; GO:0044444 cytoplasmic part; GO:0044428 nuclear part; ","GO:1901265 nucleoside phosphate binding; GO:0005515 protein binding; GO:1901363 heterocyclic compound binding; GO:0097159 organic cyclic compound binding; GO:0003824 catalytic activity; GO:0032553 ribonucleotide binding; GO:0005488 binding; GO:0032550 purine ribonucleoside binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0032559 adenyl ribonucleotide binding; GO:0030554 adenyl nucleotide binding; GO:0016740 transferase activity; GO:0017076 purine nucleotide binding; GO:0035639 purine ribonucleoside triphosphate binding; GO:0003723 RNA binding; GO:0005524 ATP binding; GO:0003725 double-stranded RNA binding; GO:0043167 ion binding; GO:0001882 nucleoside binding; GO:0000166 nucleotide binding; GO:0001730 2'-5'-oligoadenylate synthetase activity; GO:0070566 adenylyltransferase activity; GO:0032549 ribonucleoside binding; GO:0097367 carbohydrate derivative binding; GO:0016779 nucleotidyltransferase activity; GO:0003676 nucleic acid binding; GO:0046872 metal ion binding; GO:0032555 purine ribonucleotide binding; GO:0001883 purine nucleoside binding; GO:0036094 small molecule binding; GO:0016772 transferase activity, transferring phosphorus-containing groups; ","K14216","OAS; 2'-5'-oligoadenylate synthetase [EC:2.7.7.84]","hsa05162 Measles - Homo sapiens (human); hsa05168 Herpes simplex infection - Homo sapiens (human); hsa05160 Hepatitis C - Homo sapiens (human); hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human); hsa05164 Influenza A - Homo sapiens (human); ","IPR002934; IPR018952; IPR006116; ","\"Polymerase, nucleotidyl transferase domain; 2'-5'-oligoadenylate synthetase 1, domain 2/C-terminal; 2-5-oligoadenylate synthetase, N-terminal; \"\r"]
["Q9Y6N5","Sulfide:quinone oxidoreductase, mitochondrial OS=Homo sapiens OX=9606 GN=SQOR","SQOR",49.96,78.912,41.3,18,25,18,0.947,0.912,0.944,1.086,1.023,1.102,1.146,0.00624,"mitochondria\r","GO:0006790 sulfur compound metabolic process; GO:0008152 metabolic process; GO:0019418 sulfide oxidation; GO:0070221 sulfide oxidation, using sulfide:quinone oxidoreductase; GO:0044710 single-organism metabolic process; GO:0055114 oxidation-reduction process; GO:0044763 single-organism cellular process; GO:0044699 single-organism process; GO:0044237 cellular metabolic process; GO:0009987 cellular process; GO:0070813 hydrogen sulfide metabolic process; ","GO:0016020 membrane; GO:0043229 intracellular organelle; GO:0044429 mitochondrial part; GO:0031090 organelle membrane; GO:0031967 organelle envelope; GO:0044446 intracellular organelle part; GO:0005737 cytoplasm; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0005739 mitochondrion; GO:0005740 mitochondrial envelope; GO:0043231 intracellular membrane-bounded organelle; GO:0043226 organelle; GO:0044464 cell part; GO:0005622 intracellular; GO:0031975 envelope; GO:0019866 organelle inner membrane; GO:0043227 membrane-bounded organelle; GO:0005743 mitochondrial inner membrane; GO:0031966 mitochondrial membrane; GO:0044444 cytoplasmic part; ","GO:0003824 catalytic activity; GO:0005488 binding; GO:0016667 oxidoreductase activity, acting on a sulfur group of donors; GO:0070224 sulfide:quinone oxidoreductase activity; GO:0016672 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor; GO:0048037 cofactor binding; GO:0048038 quinone binding; GO:0016491 oxidoreductase activity; ","K17218",null,null,"IPR023753; ","FAD/NAD(P)-binding domain; \r"]
["Q9Y6R7","IgGFc-binding protein OS=Homo sapiens OX=9606 GN=FCGBP","FCGBP",572.01,7.6953,2.1,4,4,4,1.074,1.112,1.092,0.982,0.907,0.856,0.837,0.0121,"extracellular\r",null,"GO:0070062 extracellular exosome; GO:0043226 organelle; GO:0044421 extracellular region part; GO:0031982 vesicle; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0005576 extracellular region; GO:0043230 extracellular organelle; ","GO:0005515 protein binding; GO:0005488 binding; ",{"$nulls":3},"IPR014853; IPR002919; IPR001007; IPR001846; IPR000742; IPR025615; IPR003645; ","\"Uncharacterised domain, cysteine-rich; Trypsin Inhibitor-like, cysteine rich domain; VWFC domain; von Willebrand factor, type D domain; EGF-like domain; TILa domain; Follistatin-like, N-terminal; \"\r"]
["Q9Y6U3","Adseverin OS=Homo sapiens OX=9606 GN=SCIN","SCIN",80.488,6.7831,3.9,3,3,3,1.017,1.064,1.023,0.96,0.955,0.994,0.937,0.0267,"cytoplasm\r","GO:0030833 regulation of actin filament polymerization; GO:0065008 regulation of biological quality; GO:0010941 regulation of cell death; GO:0032273 positive regulation of protein polymerization; GO:0030835 negative regulation of actin filament depolymerization; GO:0051129 negative regulation of cellular component organization; GO:0045637 regulation of myeloid cell differentiation; GO:0051046 regulation of secretion; GO:0044699 single-organism process; GO:0030832 regulation of actin filament length; GO:0008285 negative regulation of cell proliferation; GO:0051234 establishment of localization; GO:0051130 positive regulation of cellular component organization; GO:0051693 actin filament capping; GO:0030036 actin cytoskeleton organization; GO:0042989 sequestering of actin monomers; GO:0051240 positive regulation of multicellular organismal process; GO:0032879 regulation of localization; GO:0045010 actin nucleation; GO:0032535 regulation of cellular component size; GO:0032271 regulation of protein polymerization; GO:0031334 positive regulation of protein complex assembly; GO:0051493 regulation of cytoskeleton organization; GO:0033036 macromolecule localization; GO:0008104 protein localization; GO:0051651 maintenance of location in cell; GO:0031333 negative regulation of protein complex assembly; GO:0044765 single-organism transport; GO:0046903 secretion; GO:0032507 maintenance of protein location in cell; GO:0045654 positive regulation of megakaryocyte differentiation; GO:0051494 negative regulation of cytoskeleton organization; GO:0044763 single-organism cellular process; GO:0048522 positive regulation of cellular process; GO:0051050 positive regulation of transport; GO:0010942 positive regulation of cell death; GO:0006810 transport; GO:1902589 single-organism organelle organization; GO:0010639 negative regulation of organelle organization; GO:0043254 regulation of protein complex assembly; GO:0050789 regulation of biological process; GO:0010638 positive regulation of organelle organization; GO:0043242 negative regulation of protein complex disassembly; GO:0045639 positive regulation of myeloid cell differentiation; GO:0045652 regulation of megakaryocyte differentiation; GO:0032940 secretion by cell; GO:1902904 negative regulation of supramolecular fiber organization; GO:1902905 positive regulation of supramolecular fiber organization; GO:0030837 negative regulation of actin filament polymerization; GO:0002682 regulation of immune system process; GO:0043244 regulation of protein complex disassembly; GO:0030834 regulation of actin filament depolymerization; GO:0097435 supramolecular fiber organization; GO:0051094 positive regulation of developmental process; GO:0043068 positive regulation of programmed cell death; GO:0051047 positive regulation of secretion; GO:1902903 regulation of supramolecular fiber organization; GO:2000026 regulation of multicellular organismal development; GO:0050794 regulation of cellular process; GO:0016043 cellular component organization; GO:0042127 regulation of cell proliferation; GO:0032956 regulation of actin cytoskeleton organization; GO:0043067 regulation of programmed cell death; GO:0007015 actin filament organization; GO:0043065 positive regulation of apoptotic process; GO:0044087 regulation of cellular component biogenesis; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0045597 positive regulation of cell differentiation; GO:0051239 regulation of multicellular organismal process; GO:1903706 regulation of hemopoiesis; GO:1901880 negative regulation of protein depolymerization; GO:1902578 single-organism localization; GO:0051235 maintenance of location; GO:0032330 regulation of chondrocyte differentiation; GO:0007010 cytoskeleton organization; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0061035 regulation of cartilage development; GO:0051014 actin filament severing; GO:0045595 regulation of cell differentiation; GO:1903708 positive regulation of hemopoiesis; GO:0051495 positive regulation of cytoskeleton organization; GO:0045185 maintenance of protein location; GO:0051125 regulation of actin nucleation; GO:0051049 regulation of transport; GO:0017156 calcium ion regulated exocytosis; GO:0016192 vesicle-mediated transport; GO:1901879 regulation of protein depolymerization; GO:0033043 regulation of organelle organization; GO:0032970 regulation of actin filament-based process; GO:0030838 positive regulation of actin filament polymerization; GO:0048518 positive regulation of biological process; GO:0051641 cellular localization; GO:0008064 regulation of actin polymerization or depolymerization; GO:0070727 cellular macromolecule localization; GO:0045055 regulated exocytosis; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0002684 positive regulation of immune system process; GO:0090066 regulation of anatomical structure size; GO:0051128 regulation of cellular component organization; GO:0032272 negative regulation of protein polymerization; GO:0051179 localization; GO:0050793 regulation of developmental process; GO:0051127 positive regulation of actin nucleation; GO:0044089 positive regulation of cellular component biogenesis; GO:0042981 regulation of apoptotic process; GO:0071840 cellular component organization or biogenesis; GO:0065007 biological regulation; GO:0006887 exocytosis; ","GO:0044421 extracellular region part; GO:0098862 cluster of actin-based cell projections; GO:0005903 brush border; GO:0005938 cell cortex; GO:0030054 cell junction; GO:0071944 cell periphery; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0099568 cytoplasmic region; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0044422 organelle part; GO:0043228 non-membrane-bounded organelle; GO:0070062 extracellular exosome; GO:0005856 cytoskeleton; GO:0044464 cell part; GO:0005622 intracellular; GO:1903561 extracellular vesicle; GO:0043227 membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0044430 cytoskeletal part; GO:0044446 intracellular organelle part; GO:0002102 podosome; GO:0015629 actin cytoskeleton; GO:0005576 extracellular region; GO:0043226 organelle; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0051015 actin filament binding; GO:1901981 phosphatidylinositol phosphate binding; GO:0005545 1-phosphatidylinositol binding; GO:0043167 ion binding; GO:0044877 macromolecular complex binding; GO:0005515 protein binding; GO:0001786 phosphatidylserine binding; GO:1902936 phosphatidylinositol bisphosphate binding; GO:0008092 cytoskeletal protein binding; GO:0072341 modified amino acid binding; GO:0005488 binding; GO:0005546 phosphatidylinositol-4,5-bisphosphate binding; GO:0035091 phosphatidylinositol binding; GO:0005543 phospholipid binding; GO:0003779 actin binding; GO:0008289 lipid binding; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0043168 anion binding; GO:0005509 calcium ion binding; GO:0032403 protein complex binding; ","K05768","GSN; gelsolin","hsa04666 Fc gamma R-mediated phagocytosis - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); hsa05203 Viral carcinogenesis - Homo sapiens (human); ","IPR029006; IPR007123; ","ADF-H/Gelsolin-like domain; Gelsolin-like domain; \r"]
["Q9Y6W5","Wiskott-Aldrich syndrome protein family member 2 OS=Homo sapiens OX=9606 GN=WASF2","WASF2",54.283,16.713,8.2,4,5,4,0.994,0.992,0.999,0.956,1.029,1.034,1.011,0.715,"nucleus\r","GO:0044700 single organism signaling; GO:0044085 cellular component biogenesis; GO:0007166 cell surface receptor signaling pathway; GO:0060491 regulation of cell projection assembly; GO:0032989 cellular component morphogenesis; GO:0072673 lamellipodium morphogenesis; GO:0001525 angiogenesis; GO:0030036 actin cytoskeleton organization; GO:0061515 myeloid cell development; GO:0051493 regulation of cytoskeleton organization; GO:0044419 interspecies interaction between organisms; GO:0044765 single-organism transport; GO:0030032 lamellipodium assembly; GO:0051716 cellular response to stimulus; GO:0031346 positive regulation of cell projection organization; GO:0044763 single-organism cellular process; GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway; GO:0002520 immune system development; GO:0044403 symbiosis, encompassing mutualism through parasitism; GO:0007264 small GTPase mediated signal transduction; GO:0048870 cell motility; GO:0032501 multicellular organismal process; GO:0051704 multi-organism process; GO:0050776 regulation of immune response; GO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway; GO:0006810 transport; GO:0000902 cell morphogenesis; GO:1902745 positive regulation of lamellipodium organization; GO:0048513 animal organ development; GO:0048583 regulation of response to stimulus; GO:0016601 Rac protein signal transduction; GO:0002682 regulation of immune system process; GO:0048010 vascular endothelial growth factor receptor signaling pathway; GO:1902903 regulation of supramolecular fiber organization; GO:0072359 circulatory system development; GO:0050794 regulation of cellular process; GO:0044707 single-multicellular organism process; GO:0002429 immune response-activating cell surface receptor signaling pathway; GO:0032956 regulation of actin cytoskeleton organization; GO:0048519 negative regulation of biological process; GO:0048523 negative regulation of cellular process; GO:0009653 anatomical structure morphogenesis; GO:1902578 single-organism localization; GO:0007275 multicellular organism development; GO:0038093 Fc receptor signaling pathway; GO:0007010 cytoskeleton organization; GO:0050778 positive regulation of immune response; GO:0048646 anatomical structure formation involved in morphogenesis; GO:0002253 activation of immune response; GO:0048731 system development; GO:0032231 regulation of actin filament bundle assembly; GO:0016192 vesicle-mediated transport; GO:0002376 immune system process; GO:0032970 regulation of actin filament-based process; GO:0072358 cardiovascular system development; GO:0098751 bone cell development; GO:0030031 cell projection assembly; GO:0051492 regulation of stress fiber assembly; GO:0060348 bone development; GO:0007186 G-protein coupled receptor signaling pathway; GO:0006996 organelle organization; GO:0030029 actin filament-based process; GO:0006928 movement of cell or subcellular component; GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis; GO:0048584 positive regulation of response to stimulus; GO:0051179 localization; GO:0030048 actin filament-based movement; GO:0097581 lamellipodium organization; GO:0051674 localization of cell; GO:0001568 blood vessel development; GO:0048869 cellular developmental process; GO:0051129 negative regulation of cellular component organization; GO:0038094 Fc-gamma receptor signaling pathway; GO:0044699 single-organism process; GO:0044764 multi-organism cellular process; GO:0051234 establishment of localization; GO:0006909 phagocytosis; GO:0051130 positive regulation of cellular component organization; GO:0007165 signal transduction; GO:0007154 cell communication; GO:0032990 cell part morphogenesis; GO:0022607 cellular component assembly; GO:0048858 cell projection morphogenesis; GO:0002768 immune response-regulating cell surface receptor signaling pathway; GO:0048514 blood vessel morphogenesis; GO:0007167 enzyme linked receptor protein signaling pathway; GO:0032502 developmental process; GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis; GO:0030219 megakaryocyte differentiation; GO:0051494 negative regulation of cytoskeleton organization; GO:0010591 regulation of lamellipodium assembly; GO:0001944 vasculature development; GO:0048522 positive regulation of cellular process; GO:0023052 signaling; GO:0002764 immune response-regulating signaling pathway; GO:1902589 single-organism organelle organization; GO:0010639 negative regulation of organelle organization; GO:0050789 regulation of biological process; GO:0030030 cell projection organization; GO:0001667 ameboidal-type cell migration; GO:1902904 negative regulation of supramolecular fiber organization; GO:0002431 Fc receptor mediated stimulatory signaling pathway; GO:0040011 locomotion; GO:0048856 anatomical structure development; GO:0032232 negative regulation of actin filament bundle assembly; GO:0001501 skeletal system development; GO:0007265 Ras protein signal transduction; GO:0016043 cellular component organization; GO:0016477 cell migration; GO:0002252 immune effector process; GO:0031344 regulation of cell projection organization; GO:0044087 regulation of cellular component biogenesis; GO:0050896 response to stimulus; GO:0048468 cell development; GO:0030154 cell differentiation; GO:1902743 regulation of lamellipodium organization; GO:0016032 viral process; GO:0002757 immune response-activating signal transduction; GO:0010592 positive regulation of lamellipodium assembly; GO:0009987 cellular process; GO:0030099 myeloid cell differentiation; GO:0035556 intracellular signal transduction; GO:0033043 regulation of organelle organization; GO:0051497 negative regulation of stress fiber assembly; GO:0006897 endocytosis; GO:0048518 positive regulation of biological process; GO:0030097 hemopoiesis; GO:0048534 hematopoietic or lymphoid organ development; GO:0035855 megakaryocyte development; GO:0044767 single-organism developmental process; GO:0002684 positive regulation of immune system process; GO:0051128 regulation of cellular component organization; GO:0044089 positive regulation of cellular component biogenesis; GO:0065007 biological regulation; GO:0071840 cellular component organization or biogenesis; GO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; ","GO:0044421 extracellular region part; GO:0031410 cytoplasmic vesicle; GO:0030054 cell junction; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0032991 macromolecular complex; GO:0044424 intracellular part; GO:0005623 cell; GO:0005911 cell-cell junction; GO:0005769 early endosome; GO:0043228 non-membrane-bounded organelle; GO:0005856 cytoskeleton; GO:0070062 extracellular exosome; GO:0005622 intracellular; GO:0044464 cell part; GO:0030027 lamellipodium; GO:1903561 extracellular vesicle; GO:0005768 endosome; GO:0043227 membrane-bounded organelle; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0031252 cell leading edge; GO:0042995 cell projection; GO:0043232 intracellular non-membrane-bounded organelle; GO:0012505 endomembrane system; GO:0005829 cytosol; GO:0005576 extracellular region; GO:0015629 actin cytoskeleton; GO:0043226 organelle; GO:0031209 SCAR complex; GO:0001726 ruffle; GO:0043234 protein complex; GO:0043230 extracellular organelle; GO:0044444 cytoplasmic part; ","GO:0050839 cell adhesion molecule binding; GO:0008092 cytoskeletal protein binding; GO:0005488 binding; GO:0044877 macromolecular complex binding; GO:0045296 cadherin binding; GO:0003779 actin binding; GO:0005515 protein binding; GO:0019904 protein domain specific binding; GO:0017124 SH3 domain binding; GO:0032403 protein complex binding; ","K05748","WASF2; WAS protein family, member 2","hsa05100 Bacterial invasion of epithelial cells - Homo sapiens (human); hsa05132 Salmonella infection - Homo sapiens (human); hsa04666 Fc gamma R-mediated phagocytosis - Homo sapiens (human); hsa05231 Choline metabolism in cancer - Homo sapiens (human); hsa04520 Adherens junction - Homo sapiens (human); hsa05131 Shigellosis - Homo sapiens (human); hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human); ","IPR003124; ","WH2 domain; \r"]
["Q9Y6Y8","SEC23-interacting protein OS=Homo sapiens OX=9606 GN=SEC23IP","SEC23IP",111.08,30.892,8.3,6,8,6,0.974,0.978,1.029,0.99,1.034,1.061,1.035,0.272,"nucleus\r","GO:0044085 cellular component biogenesis; GO:0051640 organelle localization; GO:0016043 cellular component organization; GO:0006901 vesicle coating; GO:0046907 intracellular transport; GO:0010256 endomembrane system organization; GO:0048207 vesicle targeting, rough ER to cis-Golgi; GO:0048208 COPII vesicle coating; GO:0044699 single-organism process; GO:0048193 Golgi vesicle transport; GO:0006903 vesicle targeting; GO:0015031 protein transport; GO:0051234 establishment of localization; GO:0051649 establishment of localization in cell; GO:0022607 cellular component assembly; GO:0065003 macromolecular complex assembly; GO:0051648 vesicle localization; GO:0048199 vesicle targeting, to, from or within Golgi; GO:0006886 intracellular protein transport; GO:0008104 protein localization; GO:0033036 macromolecule localization; GO:0034613 cellular protein localization; GO:0009987 cellular process; GO:0006461 protein complex assembly; GO:0051650 establishment of vesicle localization; GO:0071822 protein complex subunit organization; GO:0090114 COPII-coated vesicle budding; GO:0016192 vesicle-mediated transport; GO:0044763 single-organism cellular process; GO:0016050 vesicle organization; GO:0071702 organic substance transport; GO:0051656 establishment of organelle localization; GO:0043933 macromolecular complex subunit organization; GO:0051641 cellular localization; GO:0045184 establishment of protein localization; GO:0006810 transport; GO:0070727 cellular macromolecule localization; GO:0007030 Golgi organization; GO:0006996 organelle organization; GO:0061024 membrane organization; GO:0006900 membrane budding; GO:0051179 localization; GO:0070271 protein complex biogenesis; GO:0006888 ER to Golgi vesicle-mediated transport; GO:0071840 cellular component organization or biogenesis; ","GO:0030658 transport vesicle membrane; GO:0016020 membrane; GO:0005783 endoplasmic reticulum; GO:0031090 organelle membrane; GO:0031410 cytoplasmic vesicle; GO:0031982 vesicle; GO:0005737 cytoplasm; GO:0044433 cytoplasmic vesicle part; GO:0044424 intracellular part; GO:0005623 cell; GO:0030662 coated vesicle membrane; GO:0044422 organelle part; GO:0005622 intracellular; GO:0044464 cell part; GO:0098805 whole membrane; GO:0044431 Golgi apparatus part; GO:0043227 membrane-bounded organelle; GO:0012507 ER to Golgi transport vesicle membrane; GO:0043229 intracellular organelle; GO:0097708 intracellular vesicle; GO:0098588 bounding membrane of organelle; GO:0044446 intracellular organelle part; GO:0000139 Golgi membrane; GO:0012505 endomembrane system; GO:0030134 ER to Golgi transport vesicle; GO:0012506 vesicle membrane; GO:0005829 cytosol; GO:0030135 coated vesicle; GO:0030659 cytoplasmic vesicle membrane; GO:0043226 organelle; GO:0043231 intracellular membrane-bounded organelle; GO:0005793 endoplasmic reticulum-Golgi intermediate compartment; GO:0005794 Golgi apparatus; GO:0030133 transport vesicle; GO:0044444 cytoplasmic part; ","GO:0097159 organic cyclic compound binding; GO:1901363 heterocyclic compound binding; GO:0003723 RNA binding; GO:0003824 catalytic activity; GO:0005488 binding; GO:0043167 ion binding; GO:0016788 hydrolase activity, acting on ester bonds; GO:0003676 nucleic acid binding; GO:0004620 phospholipase activity; GO:0046872 metal ion binding; GO:0043169 cation binding; GO:0016787 hydrolase activity; GO:0005515 protein binding; GO:0016298 lipase activity; ",{"$nulls":3},"IPR004177; IPR013761; IPR001660; ","DDHD domain; Sterile alpha motif/pointed domain; Sterile alpha motif domain; \r"]